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Sample records for group library based

  1. ECNJEFI. A JEFI based 219-group neutron cross-section library: User's manual

    International Nuclear Information System (INIS)

    Stad, R.C.L. van der; Gruppelaar, H.

    1992-07-01

    This manual describes the contents of the ECNJEF1 library. The ECNJEF1 library is a JEF1.1 based 219-group AMPX-Master library for reactor calculations with the AMPX/SCALE-system, e.g. the PASC-3 system as implemented at the Netherlands Energy Research Foundation in Petten, Netherlands. The group cross-section data were generated with NJOY and NPTXS/XLACS-2 from the AMPX system. The data on the ECNJEF1 library allows resolved-resonance treatment by NITAWL and/or unresolved resonance self-shielding by BONAMI. These codes are based upon the Nordheim and Bondarenko methods, respectively. (author). 10 refs., 7 tabs

  2. Critical experiments analyses by using 70 energy group library based on ENDF/B-VI

    Energy Technology Data Exchange (ETDEWEB)

    Tahara, Yoshihisa; Matsumoto, Hideki [Mitsubishi Heavy Industries Ltd., Yokohama (Japan). Nuclear Energy Systems Engineering Center; Huria, H.C.; Ouisloumen, M.

    1998-03-01

    The newly developed 70-group library has been validated by comparing kinf from a continuous energy Monte-Carlo code MCNP and two dimensional spectrum calculation code PHOENIX-CP. The code employs Discrete Angular Flux Method based on Collision Probability. The library has been also validated against a large number of critical experiments and numerical benchmarks for assemblies with MOX and Gd fuels. (author)

  3. Research of the application of multi-group libraries based on ENDF/B-VII library in the reactor design

    International Nuclear Information System (INIS)

    Mi Aijun; Li Junjie

    2010-01-01

    In this paper the multi-group libraries were constructed by processing ENDF/B-VII neutron incident files into multi-group structure, and the application of the multi-group libraries in the pressurized-water reactor(PWR) design was studied. The construction of the multi-group library is realized by using the NJOY nuclear data processing system. The code can process the neutron cross section files form ENDF format to MATXS format which was required in SN code. Two dimension transport theory code of discrete ordinates DORT was used to verify the multi-group libraries and the method of the construction by comparing calculations for some representative benchmarks. We made the PWR shielding calculation by using the multi-group libraries and studied the influence of the parameters involved during the construction of the libraries such as group structure, temperatures and weight functions on the shielding design of the PWR. This work is the preparation for the construction of the multi-group library which will be used in PWR shielding design in engineering. (authors)

  4. Group cross-section processing method and common nuclear group cross-section library based on JENDL-3 nuclear data file

    International Nuclear Information System (INIS)

    Hasegawa, Akira

    1991-01-01

    A common group cross-section library has been developed in JAERI. This system is called 'JSSTDL-295n-104γ (neutron:295 gamma:104) group constants library system', which is composed of a common 295n-104γ group cross-section library based on JENDL-3 nuclear data file and its utility codes. This system is applicable to fast and fusion reactors. In this paper, firstly outline of group cross-section processing adopted in Prof. GROUCH-G/B system is described in detail which is a common step for all group cross-section library generation. Next available group cross-section libraries developed in Japan based on JENDL-3 are briefly reviewed. Lastly newly developed JSSTDL library system is presented with some special attention to the JENDL-3 data. (author)

  5. Development and verification of a 281-group WIMS-D library based on ENDF/B-VII.1

    International Nuclear Information System (INIS)

    Dong, Zhengyun; Wu, Jun; Ma, Xubo; Yu, Hui; Chen, Yixue

    2016-01-01

    Highlights: • A new WIMS-D library based on SHEM 281 energy structures is developed. • The method for calculating the lambda factor is illustrated and parameters are discussed. • The results show the improvements of this library compared with other libraries. - Abstract: The WIMS-D library based on WIMS 69 or XMAS 172 energy group structures is widely used in thermal reactor research. Otherwise, the resonance overlap effect is not taken into account in the two energy group structure, which limits the accuracy of resonance treatment. The SHEM 281 group structure is designed by the French to avoid the resonance overlap effect. In this study, a new WIMS-D library with SHEM 281 mesh is developed by using the NJOY nuclear data processing system based on the latest Evaluated Nuclear Data Library ENDF/B-VII.1. The parameters such as the thermal cut-off energy and lambda factor that depend on group structure are discussed. The lambda factor is calculated by Neutron Resonance Spectrum Calculation System and the effect of this factor is analyzed. The new library is verified through the analysis of various criticality benchmarks by using DRAGON code. The values of multiplication factor are consistent with the experiment data and the results also are improved in comparison with other WIMS libraries.

  6. COVFILS: 30-group covariance library based on ENDF/B-V

    International Nuclear Information System (INIS)

    Muir, D.W.; LaBauve, R.J.

    1981-03-01

    A library of 30-group cross sections and covariances called COVFILS has been prepared from ENDF/B-V data using the NJOY code system. COVFILS includes data on the total cross section, scattering cross sections, and the most important absorption cross sections for 1 H, 10 B, C, 16 O, Cr, Fe, Ni, Cu, and Pb. This report contains detailed descriptions of various features of the library, a listing of a FORTRAN retrieval program, and 143 plots of the multigroup cross-section uncertainties and their correlations

  7. A broad-group cross-section library based on ENDF/B-VII.0 for fast neutron dosimetry Applications

    Energy Technology Data Exchange (ETDEWEB)

    Alpan, F.A. [Westinghouse Electric Company, 1000 Westinghouse Drive, Cranberry Township, PA 16066 (United States)

    2011-07-01

    A new ENDF/B-VII.0-based coupled 44-neutron, 20-gamma-ray-group cross-section library was developed to investigate the latest evaluated nuclear data file (ENDF) ,in comparison to ENDF/B-VI.3 used in BUGLE-96, as well as to generate an objective-specific library. The objectives selected for this work consisted of dosimetry calculations for in-vessel and ex-vessel reactor locations, iron atom displacement calculations for reactor internals and pressure vessel, and {sup 58}Ni(n,{gamma}) calculation that is important for gas generation in the baffle plate. The new library was generated based on the contribution and point-wise cross-section-driven (CPXSD) methodology and was applied to one of the most widely used benchmarks, the Oak Ridge National Laboratory Pool Critical Assembly benchmark problem. In addition to the new library, BUGLE-96 and an ENDF/B-VII.0-based coupled 47-neutron, 20-gamma-ray-group cross-section library was generated and used with both SNLRML and IRDF dosimetry cross sections to compute reaction rates. All reaction rates computed by the multigroup libraries are within {+-} 20 % of measurement data and meet the U. S. Nuclear Regulatory Commission acceptance criterion for reactor vessel neutron exposure evaluations specified in Regulatory Guide 1.190. (authors)

  8. Development of a common nuclear group constants library system: JSSTDL-295n-104γ based on JENDL-3 nuclear data library

    International Nuclear Information System (INIS)

    Hasegawa, A.

    1992-01-01

    JSSTDL 295n-104γ: A common group cross-section library system has been developed in JAERI to be used in fairly wide range of applications in nuclear industry. This system is composed of a common 295n-104γ group cross-section library based on JENDL-3 nuclear data file and its utility codes. Target of this system is focused to the criticality or shielding calculations in fast and fusion reactors using ANISN, DOT, or MORSE code. Specifications of the common group constants were decided responding to the request from various nuclear data users, particularly from nuclear design group in Japan. Group structure is decided so as to cover almost all group structures currently used in our country. This library includes self-shielding factor tables for primary reactions. A routine for generating macro-scopic cross-section using the self-shielding factor table is also provided. Neutron cross-sections and photon production cross-sections are processed by Prof. GROUCH-G/B code system and γ ray transport cross-sections are generated by GAMLEG-JR. In this paper, outline and present status of the JSSTDL library system is described along with two examples adopted in JENDL-3 benchmark test. One is for shielding calculation, where effects of self-shielding factor (f-table) is shown in conjunction with the analysis of the ASPIS natural iron deep penetration experiment. Without considering resonance self-shielding effect in resonance energy region for resonant nuclides like iron, the results is completely missled in the attenuation profile calculation in the shields. The other example is fast rector criticality calculations of very small critical assemblies with very high enrichment fuel materials where some basic characteristics of this library is presented. (orig.)

  9. Generation of ENDF/B-IV based 35 group neutron cross-section library and its application in criticality studies

    International Nuclear Information System (INIS)

    Garg, S.B.; Sinha, A.

    1985-01-01

    A 35 group cross-section library with P/sub 3/-anisotropic scattering matrices and resonance self-shielding factors has been generated from the basic ENDF/B-IV cross-section files for 57 elements. This library covers the neutron energy range from 0.005 ev to 15 MeV and is well suited for the neutronics and safety analysis of fission, fusion and hybrid systems. The library is contained in two well known files, namely, ISOTXS and BRKOXS. In order to test the efficacy of this library and to bring out the importance of resonance self-shielding, a few selected fast critical assemblies representing large dilute oxide and carbide fueled uranium and plutonium based systems have been analysed. These assemblies include ZPPR/sub 2/, ZPR-3-48, ZPR-3-53, ZPR-6-6A, ZPR-6-7, ZPR-9-31 and ZEBRA-2 and are amongst those recommended by the US Nuclear Data Evaluation Working Group for testing the accuracy of cross-sections. The evaluated multiplication constants of these assemblies compare favourably with those calculated by others

  10. Production and testing of HENDL-2.1/CG coarse-group cross-section library based on ENDF/B-VII.0

    International Nuclear Information System (INIS)

    Xu Dezheng; He Zhaozhong; Zou Jun; Zeng Qin

    2010-01-01

    A coarse-group coupled neutron and photon (27n + 21γ) cross-section library HENDL-2.1/CG, based on ENDF/B-VII.0 evaluate data source, has been produced by FDS Team in Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP). HENDL-2.1/CG containing 350 nuclide cross-section files (from 1 H to 252 Cf) was generated in MATXS format with the NJOY processing system and then by compiling coarse-group problem-dependent format using the TRANSX code. In order to verify the availability and reliability of the HENDL-2.1/CG data library, requisite benchmark calculations were performed and compared with HENDL-2.0/MG fine-group coupled neutron and photon (175n + 42γ) cross-section library. In general, results using the coarse-group library showed similarly believable as fine-group library.

  11. Development of the CANDU 66-group SN transport library

    International Nuclear Information System (INIS)

    Tsang, K.T.

    2001-01-01

    The design of the shield configuration around a nuclear reactor is strongly dependent on the neutron and photon spatial and energy distributions. The nuclear heat deposition and material damage in and surrounding the reactor core are also a function of the neutron and photon distributions. Therefore, to ensure a suitable configuration of materials for shielding or heat transfer, an accurate calculation of the particle fluxes in the reactor systems is essential. The CANDU 66-group library was developed to update the cross sections that are needed to assess the performance of CANDU bulk shields. Since about 1980, shielding analysts at Atomic Energy of Canada Limited (AECL) and Ontario Power Generation Inc. (OPGI) have been using a 38-group CANDU-specific library to perform S N transport calculations. In 1994, a new CANDU 67-group cross-section library was developed. The 67-group cross-section library was developed to provide radiation-physics analysts with up-to-date nuclear data to correct deficiencies with documentation of the old library. Although there were improvements over the 38-group library, initial use showed there were some deficiencies in the 67-group library. To correct these deficiencies, the CANDU 66-group S N transport cross-section library was developed. The 66-group library is based on the 241-group cross-section library VITAMIN-B6. Collapsing and weighting of the 241-group cross sections into 66 groups were performed using the modular code system SCALE 4.4. This paper describes how the modules in the SCALE system were applied to generate the 66-group library. The CANDU 66-group library includes both core-weighted and lattice-weighted cross sections of 235 U, 238 U, and 239 Pu with, and without, delayed fission-product photons. In addition, the 66-group library contains more response functions than did the 67-group library. Finally, the CANDU 66-group library has been validated against one-dimensional benchmark problems. The results generated with

  12. Validation of the 172 group ENDFB7GX library

    International Nuclear Information System (INIS)

    Khan, Suhail Ahmad; Raj, Devesh; Karthikeyan, R.; Jagannathan, V.

    2007-01-01

    Full text: Five 172 group libraries, viz., IAEAGX, ENDFB6GX, JENDL3GX, JEFF31GX, and LWRPSGX were obtained as a part of the IAEA WIMS Library Update Project (WLUP). The first four libraries have data available for 173 nuclides up to 244 Cm. The LWRPSGX library based on JEFF3.1 point dataset is an extended library up to 252 Cf. Data for 12 more actinides and the related burnup chain were added. The five libraries were validated against known experiments in an earlier work. In general the LWRPSGX was found to be giving better results. Recently another version of 172 group library 'ENDFB7GX' has been released. In the present work we provide the results of validation of the ENDFB7GX library against the same set of experimental data and a comparison with results of other libraries. The experimental configuration data include a variety of uniform lattices with enriched UO 2 , U- metal, mixed oxide (UO 2 -PuO 2 ) fuels with H 2 O and D 2 O moderators for a wide range of enrichment, fuel diameter and ratio of moderator to fuel volume (V m /V f ). The calculations have been done using the code LATTEST which solves the single pin lattice cell problem by 1-D multi-group transport theory after cylindricalising the square or hexagonal cell boundary. The LATTEST code is an improved version of the MURLI code and is capable of providing a ready testing of any new cross section library against a set of experimental benchmark lattices collected from various sources. The calculated k eff values and certain spectral indices, where available, have been compared for all the libraries for more than hundred critical lattices. There is a general under prediction of k eff values by all libraries. The maximum under prediction is for ENDFB6GX library and the least is for JENDL3GX library. The ENDFB7GX library, in general, is found to over predict in comparison to the k eff values obtained using LWRPSGX library. While scrutinizing the basic nuclear data it was noted that the slowing down cross

  13. Thermal reactor benchmark testing of 69 group library

    International Nuclear Information System (INIS)

    Liu Guisheng; Wang Yaoqing; Liu Ping; Zhang Baocheng

    1994-01-01

    Using a code system NSLINK, AMPX master library in WIMS 69 groups structure are made from nuclides relating to 4 newest evaluated nuclear data libraries. Some integrals of 10 thermal reactor benchmark assemblies recommended by the U.S. CSEWG are calculated using rectified PASC-1 code system and compared with foreign results, the authors results are in good agreement with others. 69 group libraries of evaluated data bases in TPFAP interface file are generated with NJOY code system. The k ∞ values of 6 cell lattice assemblies are calculated by the code CBM. The calculated results are analysed and compared

  14. The WIMS 69-group library tape 166259

    International Nuclear Information System (INIS)

    Taubman, C.J.

    1975-07-01

    This note describes the contents of the WIMS 69-group library, and includes a list of nuclides with details of data file or other source of data, resonance tabulations and thermal scattering models, and a list and details of resonance tabulations. Also included are condensation spectra used to obtain group cross-sections in fast energy range, group energy boundaries, and burn-up details, including fuel and fission product burn-up chains, fission product yields and energy release data. A fission spectrum for the 69-group library is given together with a lambda and sigma p values used in the calculation of resonance cross-sections, and 2200 m/sec absorption cross-sections and resonance absorption integrals. (U.K.)

  15. ZZ MATXSLIBJ33, JENDL-3.3 based, 175 N-42 photon groups (VITAMIN-J) MATXS library for discrete ordinates multi-group

    International Nuclear Information System (INIS)

    Kosako, K.; Yamano, N.; Fukahori, T.; Shibata, K.; Hasegawa, A.

    2006-01-01

    1 - Description of program or function: JENDL-3.3 based, 175 neutron-42 photon groups (VITAMIN-J) MATXS library for discrete ordinates multi-group transport codes. Format: MATXS. Number of groups: 175 neutron, 42 gamma-ray. Nuclides: 337 nuclides contained in JENDL-3.3: H-1, H-2, He-3, He-4, Li-6, Li-7, Be-9, B-10, B-11, C-Nat, N-14, N-15, O-16, F-19, Na-23, Mg-24, Mg-25, Mg-26, Al-27, Si-28, Si-29, Si-30, P-31, S-32, S-33, S-34, S-36, Cl-35, Cl-37, Ar-40, K-39, K-40, K-41, Ca-40, Ca-42, Ca-43, Ca-44, Ca-46, Ca-48, Sc-45, Ti-46, Ti-47, Ti-48, Ti-49, Ti-50, V-Nat, Cr-50, Cr-52, Cr-53, Cr-54, Mn-55, Fe-54, Fe-56, Fe-57, Fe-58, Co-59, Ni-58, Ni-60, Ni-61, Ni-62, Ni-64, Cu-63, Cu-65, Ga-69, Ga-71, Ge-70, Ge-72, Ge-73, Ge-74, Ge-76, As-75, Se-74, Se-76, Se-77, Se-78, Se-79, Se-80, Se-82, Br-79, Br-81, Kr-78, Kr-80, Kr-82, Kr-83, Kr-84, Kr-85, Kr-86, Rb-85, Rb-87, Sr-86, Sr-87, Sr-88, Sr-89, Sr-90, Y-89, Y-91, Zr-90, Zr-91, Zr-92, Zr-93, Zr-94, Zr-95, Zr-96, Nb-93, Nb-94, Nb-95, Mo-92, Mo-94, Mo-95, Mo-96, Mo-97, Mo-98, Mo-99, Mo-100, Tc-99, Ru-96, Ru-98, Ru-99, Ru-100, Ru-101, Ru-102, Ru-103, Ru-104, Ru-106, Rh-103, Rh-105, Pd-102, Pd-104, Pd-105, Pd-106, Pd-107, Pd-108, Pd-110, Ag-107, Ag-109, Ag-110m, Cd-106, Cd-108, Cd-110, Cd-111, Cd-112, Cd-113, Cd-114, Cd-116, In-113, In-115, Sn-112, Sn-114, Sn-115, Sn-116, Sn-117, Sn-118, Sn-119, Sn-120, Sn-122, Sn-123, Sn-124, Sn-126, Sb-121, Sb-123, Sb-124, Sb-125, Te-120, Te-122, Te-123, Te-124, Te-125, Te-126, Te-127m, Te-128, Te-129m, Te-130, I-127, I-129, I-131, Xe-124, Xe-126, Xe-128, Xe-129, Xe-130, Xe-131, Xe-132, Xe-133, Xe-134, Xe-135, Xe-136, Cs-133, Cs-134, Cs-135, Cs-136, Cs-137, Ba-130, Ba-132, Ba-134, Ba-135, Ba-136, Ba-137, Ba-138, Ba-140, La-138, La-139, Ce-140, Ce-141, Ce-142, Ce-144, Pr-141, Pr-143, Nd-142, Nd-143, Nd-144, Nd-145, Nd-146, Nd-147, Nd-148, Nd-150, Pm-147, Pm-148, Pm-148m, Pm-149, Sm-144, Sm-147, Sm-148, Sm-149, Sm-150, Sm-151, Sm-152, Sm-153, Sm-154, Eu-151, Eu-152, Eu-153, Eu-154, Eu-155, Eu

  16. The universal library of fission products and delayed neutron group yields

    International Nuclear Information System (INIS)

    Koldobskiy, A.B.; Zhivun, V.M.

    1997-01-01

    A new fission product yield library based on the Semiempirical method for the estimation of their mass and charge distribution is described. Contrary to other compilations, this library can be used with all possible excitation energies of fissionable actinides. The library of delayed neutron group yields, based on the fission product yield compilation, is described as well. (author). 15 refs, 4 tabs

  17. Macro testing for group constant library TPLIB-95

    International Nuclear Information System (INIS)

    Yao Dong; Zeng Daogui; Liu Jingbo; Wang Yingming; Li Huiyun

    1996-04-01

    A macro test of the group constant library TPLIB-95 was introduced. The TPLIB-95 is an updated group constant library created by China Nuclear Data Center for LWR fuel assembly calculation program package TPFAP based on the JENDL-3.1 evaluation nuclear data library. The calculations and analyses were carried out by using five thermal reactor benchmark issues, a set of PWR zero-power critical experiments, the first cycle reactor core of 300 MW Qinshan NPP as well as the first cycle reactor core of 900 MW Daya Bay NPP. The calculation results for the thermal reactor benchmark issues showed that the maximum deviation between the calculated and measured values for spectrum indexes is large, like 6.7% for ρ 28 of BAPL-2. However, the maximum deviation for k eff is only 0.29% for TRX-2. The calculation results for zero-power critical experiments showed that the calculated value of k eff obtained by using TPLIB-95 is closer to the measured value compared with the one obtained by using the original library TPLIB. The agreement between the calculated and measured values for critical boron concentration in the first cycle reactor cores in Qinshan NPP and Daya Bay NPP is quite good. The maximum deviation for the critical boron concentration is only 15 x 10 -6 /L. (8 figs., 5 tabs.)

  18. Design criteria for the 218-group criticality safety reference library

    International Nuclear Information System (INIS)

    Westfall, R.M.; Ford, W.E. III; Webster, C.C.

    1978-01-01

    The generation of a 218-group neutron cross-section library from ENDF/B-IV data is described. Experience in selecting broad-group subsets and applying them in the analysis of critical experiments is related. Recommendations on the use of the 218-group library are made. 3 figures, 5 tables

  19. The Group Neutron Data Library (GNDL)

    International Nuclear Information System (INIS)

    Voronkov, A.V.; Zhuravlev, V.I.; Natrusova, E.G.

    1987-01-01

    The paper describes the structure, organization and basic data representation formats of the GNDL, which was developed at the M.V. Keldysh Institute of Applied Mathematics of the USSR Academy of Sciences for the purpose of neutron data storage and retrieval. A simple method for linking up applications programs with the library is proposed. (author)

  20. Use of focus groups in a library's strategic planning process.

    Science.gov (United States)

    Higa-Moore, Mori Lou; Bunnett, Brian; Mayo, Helen G; Olney, Cynthia A

    2002-01-01

    The use of focus groups to determine patron satisfaction with library resources and services is extensive and well established. This article demonstrates how focus groups can also be used to help shape the future direction of a library as part of the strategic planning process. By responding to questions about their long-term library and information needs, focus group participants at the University of Texas Southwestern Medical Center at Dallas Library contributed an abundance of qualitative patron data that was previously lacking from this process. The selection and recruitment of these patrons is discussed along with the line of questioning used in the various focus group sessions. Of special interest is the way the authors utilized these sessions to mobilize and involve the staff in creating the library's strategic plan. This was accomplished not only by having staff members participate in one of the sessions but also by sharing the project's major findings with them and instructing them in how these findings related to the library's future. The authors' experience demonstrates that focus groups are an effective strategic planning tool for libraries and emphasizes the need to share information broadly, if active involvement of the staff is desired in both the development and implementation of the library's strategic plan.

  1. Validation of a new 39 neutron group self-shielded library based on the nucleonics analysis of the Lotus fusion-fission hybrid test facility performed with the Monte Carlo code

    International Nuclear Information System (INIS)

    Pelloni, S.; Cheng, E.T.

    1985-02-01

    The Swiss LOTUS fusion-fission hybrid test facility was used to investigate the influence of the self-shielding of resonance cross sections on the tritium breeding and on the thorium ratios. Nucleonic analyses were performed using the discrete-ordinates transport codes ANISN and ONEDANT, the surface-flux code SURCU, and the version 3 of the MCNP code for the Li 2 CO 3 and the Li 2 O blanket designs with lead, thorium and beryllium multipliers. Except for the MCNP calculation which bases on the ENDF/B-V files, all nuclear data are generated from the ENDF/B-IV basic library. For the deterministic methods three NJOY group libraries were considered. The first, a 39 neutron group self-shielded library, was generated at EIR. The second bases on the same group structure as the first does and consists of infinitely diluted cross sections. Finally the third library was processed at LANL and consists of coupled 30+12 neutron and gamma groups; these cross sections are not self-shielded. The Monte Carlo analysis bases on a continuous and on a discrete 262 group library from the ENDF/B-V evaluation. It is shown that the results agree well within 3% between the unshielded libraries and between the different transport codes and theories. The self-shielding of resonance cross sections results in a decrease of the thorium capture rate and in an increase of the tritium breeding of about 6%. The remaining computed ratios are not affected by the self-shielding of cross sections. (Auth.)

  2. One-group constant libraries for nuclear equilibrium state

    Energy Technology Data Exchange (ETDEWEB)

    Mizutani, Akihiko; Sekimoto, Hiroshi [Tokyo Inst. of Tech. (Japan). Research Lab. for Nuclear Reactors

    1997-03-01

    One-group constant libraries for the nuclear equilibrium state were generated for both liquid sodium cooled MOX fuel type fast reactor and PWR type thermal reactor with Equilibrium Cell Iterative Calculation System (ECICS) using JENDL-3.2, -3, -2 and ENDF/B-VI nuclear data libraries. ECICS produced one-group constant sets for 129 heavy metal nuclides and 1238 fission products. (author)

  3. Update of PHOENIX-P 42 group library from CENDL-2

    International Nuclear Information System (INIS)

    Zhang Baocheng

    1998-01-01

    PHOENIX-P is a lattice physics code system, developed by the Westinghouse Electric Corporation (WEC), which was transplanted and used at Dayabay Nuclear Power Plant (DNPJVC). The associated multi-group (42-group) library was derived from the evaluated nuclear data of ENDF/B-5. Since the original library is from the old evaluated nuclear data, it can not meet all the requirements of reactor physics calculations of the nuclear power plant. So it is necessary to update the library with the latest version of evaluated nuclear data. To do so, based on the investigation of the old library and the information about the library, some programs were developed at China Nuclear Data Center (CNDC) to produce PHOENIX-P format data sets mainly from CENDL-2 and the new data were used to supersede the old ones of the PHOENIX-P library

  4. Generation of broad-group neutron/photon cross-section libraries for shielding applications

    International Nuclear Information System (INIS)

    Ingersoll, D.T.; Roussin, R.W.; Fu, C.Y.; White, J.E.

    1989-01-01

    The generation and use of multigroup cross-section libraries with broad energy group structures is primarily for the economy of computer resources. Also, the establishment of reference broad-group libraries is desirable in order to avoid duplication of effort, both in terms of the data generation and verification, and to assure a common data base for all participants in a specific project. Uncertainties are inevitably introduced into the broad-group cross sections due to approximations in the grouping procedure. The dominant uncertainty is generally with regard to the energy weighting function used to average the pointwise or fine-group data within a single broad group. Intelligent choice of the weighting functions can reduce such uncertainties. Also, judicious selection of the energy group structure can help to reduce the sensitivity of the computed responses to the weighting function, at least for a selected set of problems. Two new multigroup cross section libraries have been recently generated from ENDF/B-V data for two specific shielding applications. The first library was prepared for use in sodium-cooled reactor systems and is available in both broad-group structures. The second library, just recently completed, was prepared for use in air-over-ground environments and is available in a broad-group (46-neutron, 23-photon) energy structure. The selection of the specific group structures and weighting functions was an important part of the generation of both libraries

  5. Development of the CPXSD Methodology for Generation of Fine-Group Libraries for Shielding Applications

    International Nuclear Information System (INIS)

    Alpan, F. Arzu; Haghighat, Alireza

    2005-01-01

    Multigroup cross sections are one of the major factors that cause uncertainties in the results of deterministic transport calculations. Thus, it is important to prepare effective cross-section libraries that include an appropriate group structure and are based on an appropriate spectrum. There are several multigroup cross-section libraries available for particular applications. For example, the 47-neutron, 20-gamma group BUGLE library that is derived from the 199-neutron, 42-gamma group VITAMIN-B6 library is widely used for light water reactor (LWR) shielding and pressure vessel dosimetry applications. However, there is no publicly available methodology that can construct problem-dependent libraries. Thus, the authors have developed the Contributon and Point-wise Cross Section Driven (CPXSD) methodology for constructing effective fine- and broad-group structures. In this paper, new fine-group structures were constructed using the CPXSD, and new fine-group cross-section libraries were generated. The 450-group LIB450 and 589-group LIB589 libraries were developed for neutrons sensitive to the fast and thermal energy ranges, respectively, for LWR shielding problems. As compared to a VITAMIN-B6-like library, the new fine-group library developed for fast neutron dosimetry calculations resulted in closer agreement to the continuous-energy predictions. For example, for the fast neutron cavity dosimetry, ∼4% improvement was observed for the 237 Np(n,f) reaction rate. For the thermal neutron 1 H(n, γ) reaction, a maximum improvement of ∼14% was observed in the reaction rate at the middowncomer position

  6. AUTOMATION BASED LIBRARY MANAGEMENT IN DEPOK PUBLIC LIBRARY IN THE CONTEXT OF RITUAL PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Rafiqa Maulidia

    2017-06-01

    Full Text Available Library management using manual system is no longer adequate to handle the workload in the library routines, librarians must use application of library automation. To provide a good working performance, librarians use strategy, competences and certain habits, which are referred to as a ritual performance. The performance of the ritual is the demonstration of competence spontaneously by individuals in dealing with individuals, groups and organizations, which contains elements of personal ritual, the work ritual, social ritual, and organization ritual. The research focuses in the automation based library management in the context of the performance of the ritual. This study used a qualitative approach with case study method. The findings suggest that the personal ritual shows the personal habits of librarians to do their tasks, ritual librarian's work show responsibility towards their duties, social rituals strengthen the emotional connection between librarians and leaders, as well as ritual organizations suggest the involvement of librarians in giving their contribution in decision making. Conclusions of this study shows that the performance of rituals librarian at Depok Public Library gives librarians the skills to implement automation systems in the library management, and reflect the values of responsibility, mutual trust, and mutual respect.   Key words : Library Management, Library Automation, Ritual Performance, Ritual Performance Value

  7. ACT-1000. Group activation cross-section library for WWER-1000 type reactors

    Energy Technology Data Exchange (ETDEWEB)

    Zolotarev, K I; Pashchenko, A B [National Research Centre - A.I. Leipunsky Institute for Physics and Power Engineering, Obninsk (Russian Federation)

    2001-10-01

    The ACT-1000, a problem-oriented library of group-averaged activation cross-sections for WWER-1000 type reactors, is based on evaluated microscopic cross-section data files. The ACT-1000 data library was designed for calculating induced activity for the main dose-generated nuclides contained in WWER-1000 structural materials. In preparing the ACT-1000 library, 47 group-averaged cross-section data for the 10{sup -9}-17.33 MeV energy range were used to calculate the spatial-energy neutron flux distribution. (author)

  8. Benchmarking of the 99-group ANSL-V library

    International Nuclear Information System (INIS)

    Wright, R.Q.; Ford, W.E. III; Greene, N.M.; Petrie, L.M.; Primm, R.T. III; Westfall, R.M.

    1987-01-01

    The purpose of this paper is to present thermal benchmark data testing results for the BAPL-1, TRX-1, and SEEP-1 lattices, using selected processed cross-sections from the ANSL-V 99-group library. 7 refs., 1 tab

  9. Experimental OAI-Based Digital Library Systems

    Science.gov (United States)

    Nelson, Michael L. (Editor); Maly, Kurt (Editor); Zubair, Mohammad (Editor); Rusch-Feja, Diann (Editor)

    2002-01-01

    The objective of Open Archives Initiative (OAI) is to develop a simple, lightweight framework to facilitate the discovery of content in distributed archives (http://www.openarchives.org). The focus of the workshop held at the 5th European Conference on Research and Advanced Technology for Digital Libraries (ECDL 2001) was to bring researchers in the area of digital libraries who are building OAI based systems so as to share their experiences, problems they are facing, and approaches they are taking to address them. The workshop consisted of invited talks from well-established researchers working in building OAI based digital library system along with short paper presentations.

  10. A Novel Public Library-Based Sexually Transmitted Infection Screening Program for Younger High-Risk Groups in Omaha, Nebraska, USA.

    Science.gov (United States)

    Delair, Shirley F; Lyden, Elizabeth R; O'Keefe, Anne L; Simonsen, Kari A; Nared, Sherri R; Berthold, Elizabeth A; Watanabe-Galloway, Shinobu

    2016-04-01

    Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are the two most commonly reported sexually transmitted infections (STIs) in the United States (U.S.) and Douglas County, Nebraska has STI rates consistently above the U.S. average. The Douglas County Health Department (DCHD) developed an outreach CT and NG screening program in public libraries to address the problem beyond the traditional STI clinic setting. This study evaluates the effectiveness of the program and identifies factors predictive of CT and NG infections. A retrospective review of surveys of library patrons and DCHD traditional STI clinic clients who submitted urine tests for CT and NG from June 2010 through April 2014 was done. Chi square, Fisher exact, Student's t tests, univariate and multivariate logistic regression were conducted. A total of 977 library records and 4871 DCHD clinic records were reviewed. The percent positive was lower in the library than in the traditional clinic for CT (9.9 vs. 11.2 %) and NG (2.74 vs. 5.3 %) (p = 0.039 and p Library clients were more likely to be 19 years and younger (OR 6.14, 95 % CI: 5.0, 7.5), Black (OR 3.4, 95 % CI: 2.8, 4.1), and asymptomatic (OR 12.4, 95 % CI: 9.9, 15.5) compared to traditional clinic clients. The library STI screening program effectively reaches a younger, asymptomatic, and predominantly Black population compared to a traditional health department clinic site.

  11. Validation of DRAGON code in connection with WIMS-AECL/RFSP code system based on ENDF/B-VI library and two group model

    International Nuclear Information System (INIS)

    Hong, In Seob; Suk, Ho Chun; Kim, Soon Young; Jo, Chang Keun

    2002-06-01

    The major objective of this research is to validate the incremental cross section property of DRAGON code in connection with WIMS-AECL/DRAGON/RFSP code system with ENDF/B-VI library and full 2G calculation model. The direct comparison between the incremental cross section results calculated by DRAGON with ENDF/B-VI and ENDF/B-V and MULTICELL with ENDF/B-V indicate that there are not much differences between the incremental cross sections of DRAGON with ENDF/B-V and ENDF/B-VI, but there exists large discrepancies between the results of DRAGON and those of MULTICELL. In the analysis of the difference between calculated and measured reactivity worths of various types of control devices during Phase-B Post-Simulation of Wolsong Units 2, 3 and 4, WIMS-AECL/DRAGON/RFSP analysis well agrees with those of previous WIMS-AECL /MULTICELL/RFSP analysis within very small differences. From those results, we can conclude that DRAGON code can be used as a general purpose incremental cross section generation tool for not only the natural uranium fuel but also slightly enriched fuel such as RU or SEU, to cover the shortcomings of natural uranium based MULTICELL code

  12. Automation Based Library Management in Depok Public Library In The Context of Ritual Performance

    Directory of Open Access Journals (Sweden)

    Rafiqa Maulidia

    2018-01-01

    Full Text Available Library management using manual system is no longer adequate to handle the workload in the library routines, librarians must use application of library automation. To provide a good working performance, librarians use strategy, competences and certain habits, which are referred to as a ritual performance. The performance of the ritual is the demonstration of competence spontaneously by individuals in dealing with individuals, groups and organizations, which contains elements of personal ritual, the work ritual, social ritual, and organization ritual. The research focuses in the automation based library management in the context of the performance of the ritual. This study used a qualitative approach with case study method. The findings suggest that the personal ritual shows the personal habits of librarians to do their tasks, ritual librarian's work show responsibility towards their duties, social rituals strengthen the emotional connection between librarians and leaders, as well as ritual organizations suggest the involvement of librarians in giving their contribution in decision making. Conclusions of this study shows that the performance of rituals librarian at Depok Public Library gives librarians the skills to implement automation systems in the library management, and reflect the values of responsibility, mutual trust, and mutual respect.

  13. Comparison of measurements and calculations of fuel for different structures in the libraries of effective sections (44 groups/238 groups)

    International Nuclear Information System (INIS)

    Rodriguez Rivada, A.; Tore, C.

    2013-01-01

    The study was conducted for the use of the sections effective in 44 groups, based on the libraries of effective sections ENDF/B-V, for the calculation of the isotopy of the spent fuel. These effective sections have been developed to be used in the system codes SCALE for the analysis the fresh nuclear fuel as the spent and their radioactive waste.

  14. SPOTS4. Group data library and computer code, preparing ENDF/B-4 data for input to LEOPARD

    International Nuclear Information System (INIS)

    Kim, J.D.; Lee, J.T.

    1981-09-01

    The magnetic tape SPOTS4 contains in file 1 a data library to be used as input to the SPOTS4 program which is contained in file 2. The data library is based on ENDF/B-4 and consists of two parts in TEMPEST format (246 groups) and MUFT format (54 groups) respectively. From this library the SPOTS4 program produces a 172 + 54 group library for LEOPARD input. A copy of the magnetic tape is available from the IAEA Nuclear Data Section. (author)

  15. Curriculum-based neurosurgery digital library.

    Science.gov (United States)

    Langevin, Jean-Philippe; Dang, Thai; Kon, David; Sapo, Monica; Batzdorf, Ulrich; Martin, Neil

    2010-11-01

    Recent work-hour restrictions and the constantly evolving body of knowledge are challenging the current ways of teaching neurosurgery residents. To develop a curriculum-based digital library of multimedia content to face the challenges in neurosurgery education. We used the residency program curriculum developed by the Congress of Neurological Surgeons to structure the library and Microsoft Sharepoint as the user interface. This project led to the creation of a user-friendly and searchable digital library that could be accessed remotely and throughout the hospital, including the operating rooms. The electronic format allows standardization of the content and transformation of the operating room into a classroom. This in turn facilitates the implementation of a curriculum within the training program and improves teaching efficiency. Future work will focus on evaluating the efficacy of the library as a teaching tool for residents.

  16. Verification and validation of multi-group library MUSE1.0 created from ENDF/B-VII.0

    International Nuclear Information System (INIS)

    Chen Yixue; Wu Jun; Yang Shouhai; Zhang Bin; Lu Daogang; Chen Chaobin

    2010-01-01

    A multi-group library set named MUSE1.0 with 172-neutron group and 42-photon group is produced based on ENDF/B-VII.0 using NJOY code. Weight function of the multi-group library set is taken from the Vitanim-e library and the max legendre order of scattering matrix is six. All the nuclides have thermal scattering data created using free-gas scattering law and 10 Bondarenko background cross sections se lected to generate the self-shielded multi-group cross sections. The final libraries have GENDF-format, MATXS-format and ACE-multi-group sub-libraries and each sub-library generated under 4 temperatures(293 K,600 K,800 K and 900 K). This paper provides a summary of the procedure to produce the library set and a detail description of the validation of the multi-group library set by several critical benchmark devices and shielding benchmark devices using MCNP code. The ability to handle the thermal neutron transport and resonance self-shielding problems are investigated specially. In the end, we draw the conclusion that the multi-group libraries produced is credible and can be used in the R and D process of Supercritical Water Reactor Design. (authors)

  17. Zero-base budgeting and the library.

    Science.gov (United States)

    Sargent, C W

    1978-01-01

    This paper describes the application of zero-base budgeting to libraries and the procedures involved in setting up this type of budget. It describes the "decision packages" necessary when this systmem is employed, as well as how to rank the packages and the problems which are related to the process. Zero-base budgeting involves the entire staff of a library, and the incentive engendered makes for a better and more realistic budget. The paper concludes with the problems which one might encounter in zero-base budgeting and the major benefits of the system. PMID:626795

  18. Identification of toxic cyclopeptides based on mass spectral library matching

    Directory of Open Access Journals (Sweden)

    Boris L. Milman

    2014-08-01

    Full Text Available To gain perspective on the use of tandem mass spectral libraries for identification of toxic cyclic peptides, the new library was built from 263 mass spectra (mainly MS2 spectra of 59 compounds of that group, such as microcystins, amatoxins, and some related compounds. Mass spectra were extracted from the literature or specially acquired on ESI-Q-ToF and MALDI-ToF/ToF tandem instruments. ESI-MS2 product-ion mass spectra appeared to be rather close to MALDI-ToF/ToF fragment spectra which are uncommon for mass spectral libraries. Testing of the library was based on searches where reference spectra were in turn cross-compared. The percentage of 1st rank correct identifications (true positives was 70% in a general case and 88–91% without including knowingly defective (‘one-dimension’ spectra as test ones. The percentage of 88–91% is the principal estimate for the overall performance of this library that can be used in a method of choice for identification of individual cyclopeptides and also for group recognition of individual classes of such peptides. The approach to identification of cyclopeptides based on mass spectral library matching proved to be the most effective for abundant toxins. That was confirmed by analysis of extracts from two cyanobacterial strains.

  19. Multi-Group Library Generation with Explicit Resonance Interference Using Continuous Energy Monte Carlo Calculation

    Energy Technology Data Exchange (ETDEWEB)

    Park, Ho Jin; Cho, Jin Young [KAERI, Daejeon (Korea, Republic of); Kim, Kang Seog [Oak Ridge National Laboratory, Oak Ridge (United States); Hong, Ser Gi [Kyung Hee University, Yongin (Korea, Republic of)

    2016-05-15

    In this study, multi-group cross section libraries for the DeCART code were generated using a new procedure. The new procedure includes generating the RI tables based on the MC calculations, correcting the effective fission product yield calculations, and considering most of the fission products as resonant nuclides. KAERI (Korea Atomic Energy Research Institute) has developed the transport lattice code KARMA (Kernel Analyzer by Ray-tracing Method for fuel Assembly) and DeCART (Deterministic Core Analysis based on Ray Tracing) for a multi-group neutron transport analysis of light water reactors (LWRs). These codes adopt the method of characteristics (MOC) to solve the multi-group transport equation and resonance fixed source problem, the subgroup and the direct iteration method with resonance integral tables for resonance treatment. With the development of the DeCART and KARMA code, KAERI has established its own library generation system for a multi-group transport calculation. In the KAERI library generation system, the multi-group average cross section and resonance integral (RI) table are generated and edited using PENDF (point-wise ENDF) and GENDF (group-wise ENDF) produced by the NJOY code. The new method does not need additional processing because the MC method can handle any geometry information and material composition. In this study, the new method is applied to the dominant resonance nuclide such as U{sup 235} and U{sup 238} and the conventional method is applied to the minor resonance nuclides. To examine the newly generated multi-group cross section libraries, various benchmark calculations such as pin-cell, FA, and core depletion problem are performed and the results are compared with the reference solutions. Overall, the results by the new method agree well with the reference solution. The new procedure based on the MC method were verified and provided the multi-group library that can be used in the SMR nuclear design analysis.

  20. Development of libraries for ORIGEN2 code based on JENDL-3.2

    Energy Technology Data Exchange (ETDEWEB)

    Suyama, Kenya; Katakura, Jun-ichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Ishikawa, Makoto; Ohkawachi, Yasushi

    1998-03-01

    The working Group of JNDC `Nuclide Generation Evaluation` has launched a project to make libraries for ORIGEN2 code based on the latest nuclear data library `JENDL-3.2` for current design of LWR and FBR fuels. Many of these libraries are under validation. (author)

  1. Dendrimer-based dynamic combinatorial libraries

    NARCIS (Netherlands)

    Chang, T.; Meijer, E.W.

    2005-01-01

    The aim of this project is to create water-sol. dynamic combinatorial libraries based upon dendrimer-guest complexes. The guest mols. are designed to bind to dendrimers using multiple secondary interactions, such as electrostatics and hydrogen bonding. We have been able to incorporate various guest

  2. Role of ''standard'' fine-group cross section libraries in shielding analysis

    International Nuclear Information System (INIS)

    Weisbin, C.R.; Roussin, R.W.; Oblow, E.M.; Cullen, D.E.; White, J.E.; Wright, R.Q.

    1977-01-01

    The Divisions of Magnetic Fusion Energy (DMFE) and Reactor Development and Demonstration (DRDD) of the United States Energy Research and Development Administration (ERDA) have jointly sponsored the development of a 171 neutron, 36 gamma ray group pseudo composition independent cross section library based upon ENDF/B-IV. This library (named VITAMIN-C and packaged by RSIC as DLC-41) is intended to be generally applicable to fusion blanket and LMFBR core and shield analysis. The purpose of this paper is to evaluate this library as a possible candidate for specific designation as a ''standard'' in light of American Nuclear Society standards for fine-group cross section data sets. The rationale and qualification procedure for such a standard are discussed. Finally, current limitations and anticipated extensions to this processed data file are described

  3. America's Star Libraries, 2010: Top-Rated Libraries

    Science.gov (United States)

    Lyons, Ray; Lance, Keith Curry

    2010-01-01

    The "LJ" Index of Public Library Service 2010, "Library Journal"'s national rating of public libraries, identifies 258 "star" libraries. Created by Ray Lyons and Keith Curry Lance, and based on 2008 data from the IMLS, it rates 7,407 public libraries. The top libraries in each group get five, four, or three stars. All included libraries, stars or…

  4. The Cost of Library Services: Activity-Based Costing in an Australian Academic Library.

    Science.gov (United States)

    Robinson, Peter; Ellis-Newman, Jennifer

    1998-01-01

    Explains activity-based costing (ABC), discusses the benefits of ABC to library managers, and describes the steps involved in implementing ABC in an Australian academic library. Discusses the budgeting process in universities, and considers benefits to the library. (Author/LRW)

  5. BARC 75 - A 75 group neutron-photon coupled cross-section library with P5- anisotropic scattering matrices

    International Nuclear Information System (INIS)

    Garg, S.B.

    1990-01-01

    A 75 group neutron-photon coupled cross-section library has been developed for 42 reactor nuclides utilizing the basic cross-section files - ENDF/B-IV for neutrons and DLC-7F for photons. 50 neutron energy groups and gamma energy groups are included in this library which should be well suited to carry out safety, shielding and core physics studies of nuclear reactors based on fission or fusion processes. This library is also adequate for oil logging and mineral exploration investigations. (author). 11 refs., 3 tabs

  6. JDATAVIEWER – JAVA-Based Charting Library

    CERN Document Server

    Kruk, G

    2009-01-01

    The JDataViewer is a Java-based charting library developed at CERN, with powerful, extensible and easy to use function editing capabilities. Function edition is heavily used in Control System applications, but poorly supported in products available on the market. The JDataViewer enables adding, removing and modifying function points graphically (using a mouse) or by editing a table of values. Custom edition strategies are supported: developer can specify an algorithm that reacts to the modification of a given point in the function by automatically adapting all other points. The library provides all typical 2D plotting types (scatter, polyline, area, bar, HiLo, contour), as well as data point annotations and data indicators. It also supports common interactors to zoom and move the visible view, or to select and highlight function segments. A clear API is provided to configure and customize all chart elements (colors, fonts, data ranges ...) programmatically, and to integrate non-standard rendering types, inter...

  7. Web-Based Instruction: A Guide for Libraries, Third Edition

    Science.gov (United States)

    Smith, Susan Sharpless

    2010-01-01

    Expanding on the popular, practical how-to guide for public, academic, school, and special libraries, technology expert Susan Sharpless Smith offers library instructors the confidence to take Web-based instruction into their own hands. Smith has thoroughly updated "Web-Based Instruction: A Guide for Libraries" to include new tools and trends,…

  8. Creating new library services through collaboration with resident groups : Aimimg at human resource development and information literacy education in ways only libraries can do : Study on activities of an NPO called Ueda Library Club

    Science.gov (United States)

    Morita, Utako

    Creating new library services through collaboration with resident groups : Aimimg at human resource development and information literacy education in ways only libraries can do : Study on activities of an NPO called Ueda Library Club

  9. Development of multi-group xs libraries for the gfr 2400 reactor

    International Nuclear Information System (INIS)

    Cerba, Š.; Vrban, B.; Lüley, J.; Necas, V.

    2016-01-01

    GFR 2400 is considered as a conceptual design of the large scale GEN IV Gas-Cooled Fast Reactor. In general, the GEN IV technologies are seen as reliable but also very challenging reactor concepts. Since GFR 2400 lacks any experimental data, the questions on its safety are even more complex and the assessment of its performance could be made only based on computational experience. The paper deals with the development process of multi-group XS libraries based on a hybrid deterministic-Stochastic methodology, using the NJOY99, TRANSX, DIF3D, PARTISN and MCNP5 codes. A new optimized 25 group SBJ E 71 2 5G cross section library was developed based on ENDF/B-VII.1 evaluated data, ZZ-KAFAX-E70 background cross sections and GFR 2400 neutron spectrum. The created library was validated through integral experiments evaluated on the HEX-Z deterministic models in DIF3D. The results were also compared with MCNP5 calculations. (authors)

  10. Library-Based Learning in an Information Society.

    Science.gov (United States)

    Breivik, Patricia Senn

    1986-01-01

    The average academic library has great potential for quality nonclassroom learning benefiting students, faculty, alumni, and the local business community. The major detriments are the limited perceptions about libraries and librarians among campus administrators and faculty. Library-based learning should be planned to be assimilated into overall…

  11. Generation of a Broad-Group HTGR Library for Use with SCALE

    International Nuclear Information System (INIS)

    Ellis, Ronald James; Lee, Deokjung; Wiarda, Dorothea; Williams, Mark L.; Mertyurek, Ugur

    2012-01-01

    With current and ongoing interest in high temperature gas reactors (HTGRs), the U.S. Nuclear Regulatory Commission (NRC) anticipates the need for nuclear data libraries appropriate for use in applications for modeling, assessing, and analyzing HTGR reactor physics and operating behavior. The objective of this work was to develop a broad-group library suitable for production analyses with SCALE for HTGR applications. Several interim libraries were generated from SCALE fine-group 238- and 999-group libraries, and the final broad-group library was created from Evaluated Nuclear Data File/B Version ENDF/B-VII Release 0 cross-section evaluations using new ORNL methodologies with AMPX, SCALE, and other codes. Furthermore, intermediate resonance (IR) methods were applied to the HTGR broadgroup library, and lambda factors and f-factors were incorporated into the library s nuclear data files. A new version of the SCALE BONAMI module named BONAMI-IR was developed to process the IR data in the new library and, thus, eliminate the need for the CENTRM/PMC modules for resonance selfshielding. This report documents the development of the HTGR broad-group nuclear data library and the results of test and benchmark calculations using the new library with SCALE. The 81-group library is shown to model HTGR cases with similar accuracy to the SCALE 238-group library but with significantly faster computational times due to the reduced number of energy groups and the use of BONAMI-IR instead of BONAMI/CENTRM/PMC for resonance self-shielding calculations.

  12. EURLIB-LWR-45/16 and - 15/5. Two board group libraries for LWR-shielding problems

    Energy Technology Data Exchange (ETDEWEB)

    Herrnberger, V

    1982-04-01

    Specifications of the broad group cross section libraries EURLIB-LWR-45/16 and -15/5 are given. They are based on EURLIB-III data and produced for LWR shielding problems. The elements considered are H, C{sub 12}, O, Na, Al, Si, Ca, Cr, Mn, Fe, Ni, Zr, U{sub 235}, U{sub 238}. The cross section libraries are available upon request from EIR, RSIC, NEA-CPL and IAEA-NDS. (author) Refs, figs, tabs

  13. ORIGEN-2 libraries based on JENDL-3.2 for PWR-MOX fuel

    Energy Technology Data Exchange (ETDEWEB)

    Matsumoto, Hideki; Onoue, Masaaki; Tahara, Yoshihisa [Mitsubishi Heavy Industries Ltd., Tokyo (Japan)

    2001-08-01

    A set of ORIGEN-2 libraries for PWR MOX fuel was developed based on JENDL-3.2 in the Working Group on Evaluation of Nuclide Production, Japanese Nuclear Data Committee. The calculational model generating ORIGEN-2 libraries of PWR MOX is explained here in detail. The ORIGEN-2 calculation with the new ORIGEN-2 MOX library can predict the nuclides contents within 10% for U and Pu isotopes and 20% for both minor actinides and main FPs. (author)

  14. Generation of the V4.2m5 and AMPX and MPACT 51 and 252-Group Libraries with ENDF/B-VII.0 and VII.1

    International Nuclear Information System (INIS)

    Kim, Kang Seog

    2016-01-01

    The evaluated nuclear data file (ENDF)/B-7.0 v4.1m3 MPACT 47-group library has been used as a main library for the Consortium for Advanced Simulation of Light Water Reactors (CASL) neutronics simulator in simulating pressurized water reactor (PWR) problems. Recent analysis for the high void boiling water reactor (BWR) fuels and burnt fuels indicates that the 47-group library introduces relatively large reactivity bias. Since the 47- group structure does not match with the SCALE 6.2 252-group boundaries, the CASL Virtual Environment for Reactor Applications Core Simulator (VERA-CS) MPACT library must be maintained independently, which causes quality assurance concerns. In order to address this issue, a new 51-group structure has been proposed based on the MPACT 47- g and SCALE 252-g structures. In addition, the new CASL library will include a 19-group structure for gamma production and interaction cross section data based on the SCALE 19- group structure. New AMPX and MPACT 51-group libraries have been developed with the ENDF/B-7.0 and 7.1 evaluated nuclear data. The 19-group gamma data also have been generated for future use, but they are only available on the AMPX 51-g library. In addition, ENDF/B-7.0 and 7.1 MPACT 252-g libraries have been generated for verification purposes. Various benchmark calculations have been performed to verify and validate the newly developed libraries.

  15. Generation of the V4.2m5 and AMPX and MPACT 51 and 252-Group Libraries with ENDF/B-VII.0 and VII.1

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kang Seog [Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States). Consortium for Advanced Simulation of LWRs (CASL)

    2016-12-12

    The evaluated nuclear data file (ENDF)/B-7.0 v4.1m3 MPACT 47-group library has been used as a main library for the Consortium for Advanced Simulation of Light Water Reactors (CASL) neutronics simulator in simulating pressurized water reactor (PWR) problems. Recent analysis for the high void boiling water reactor (BWR) fuels and burnt fuels indicates that the 47-group library introduces relatively large reactivity bias. Since the 47- group structure does not match with the SCALE 6.2 252-group boundaries, the CASL Virtual Environment for Reactor Applications Core Simulator (VERA-CS) MPACT library must be maintained independently, which causes quality assurance concerns. In order to address this issue, a new 51-group structure has been proposed based on the MPACT 47- g and SCALE 252-g structures. In addition, the new CASL library will include a 19-group structure for gamma production and interaction cross section data based on the SCALE 19- group structure. New AMPX and MPACT 51-group libraries have been developed with the ENDF/B-7.0 and 7.1 evaluated nuclear data. The 19-group gamma data also have been generated for future use, but they are only available on the AMPX 51-g library. In addition, ENDF/B-7.0 and 7.1 MPACT 252-g libraries have been generated for verification purposes. Various benchmark calculations have been performed to verify and validate the newly developed libraries.

  16. Development of a 1200 fine group nuclear data library for advanced nuclear systems

    Institute of Scientific and Technical Information of China (English)

    Jun Zou; Lei-Ming Shang; Fang Wang; Li-Juan Hao

    2017-01-01

    Accurate and reliable nuclear data libraries are essential for calculation and design of advanced nuclear systems.A 1200 fine group nuclear data library Hybrid Evaluated Nuclear Data Library/Fine Group (HENDL/FG) with neutrons of up to 150 MeV has been developed to improve the accuracy of neutronics calculations and analysis.Corrections of Doppler,resonance self-shielding,and thermal upscatter effects were done for HENDL/FG.Shielding and critical safety benchmarks were performed to test the accuracy and reliability of the library.The discrepancy between calculated and measured nuclear parameters fell into a reasonable range.

  17. Generation of a library of two-group diffusion and kinetics parameters for DYN3D

    International Nuclear Information System (INIS)

    Petkov, P.T.; Christoskov, I.D.; Kamenov, K.; Antov, A.

    2002-01-01

    A library of two-group diffusion and kinetics parameters has been generated for the neutron kinetics code DYN3D for analysis of reactivity initiated accidents for the WWER-440 reactors, based on the MAGRU approximation methodology for the diffusion and kinetics parameters. The accuracy of this methodology has been tested and the conclusion is that it is not adequate. A new approximation methodology, based on interpolation for the most widely varying parameters, i.e. the moderator temperature and density, and on approximation for all other independent parameters, is presented. The methodology of calculation of the kinetics parameters using primary data from ENDF-B/VI is described in detail (Authors)

  18. Improvements on burnup chain model and group cross section library in the SRAC system

    International Nuclear Information System (INIS)

    Akie, Hiroshi; Okumura, Keisuke; Takano, Hideki; Ishiguro, Yukio; Kaneko, Kunio.

    1992-01-01

    Data and functions of the cell burnup calculation of the SRAC system were revised to improve mainly the accuracy of the burnup calculation of high conversion light water reactors (HCLWRs). New burnup chain models were developed in order to treat fission products (FPs) and actinide nuclides in detail. Group cross section library, SRACLIB-JENDL2, was generated based on JENDL-2 nuclear data file. In generating this library, emphasis was placed on FPs and actinides. Also revised were the data such as the average energy release per fission for various actinides. These improved data were verified by performing the burnup analysis of PWR spent fuels. Some new functions were added to the SRAC system for the convenience to yield macroscopic cross sections used in the core burnup process. (author)

  19. WWER440 few group data library preparation and its application in MOBY-DICK modular system

    International Nuclear Information System (INIS)

    Krysl, V.; Mikolas, P.; Svarny, J.

    2002-01-01

    Paper provides summary of methodology of few-group library preparation with emphasis on new features of assemblies, like fuel assemblies with Gd burnable poison or Control Fuel Assembly with Hf plates. Special attention is devoted to the transient part (coupler) of Control Fuel Assembly from the point of view of boundary conditions preparation. Based of this methodology prepared library is implemented into macro code for different number of axial meshes for both coarse and fine mesh diffusion calculations. Problems with local power peaking calculations in WWER-440 cores are closely connected with the correct modeling of the power perturbations in the neighbourhood of Control Fuel Assembly coupler. The new version of MOBY-DICK provided with the new few group data library can assess most of effects induced by insertion of Control Fuel Assembly in the core including effects of newly designed Hf plates in the coupler of Control Fuel Assembly. Compatibility of transport and diffusion calculation was taken into account in the analysis of Control Fuel Assembly movement without/with Hf plates (Authors)

  20. A library of neutron data for calculating group constants

    International Nuclear Information System (INIS)

    Koshcheev, V.N.; Nikolaev, M.N.

    1987-01-01

    This paper describes the first version of a computerized library evaluated neutron data files (FOND) which includes data on the 67 most important nuclear reactor and radiation shielding materials. The data are represented in the ENDF/B format. The sources of data were the results of evaluations of data from differential neutron physics experiments conducted both in the USSR and abroad. The first version of the FOND library is not intended for use in reactor and shielding design calculations, but rather to serve as the basis for developing a corrected version which will guarantee adequate description of the results of a representative set of macroscopic experiments, and for generating multigroup constant systems in methodological research. (author)

  1. Information provision in medical libraries: An evidence based ...

    African Journals Online (AJOL)

    The paper examined information provision in special libraries such as medical libraries. It provides an overview of evidence based practice as a concept for information provision by librarians. It specifically proffers meaning to the term evidence as used in evidence based practice and to evidence based medicine from where ...

  2. Towards Knowledge-Based Digital Libraries

    NARCIS (Netherlands)

    Feng, L.; Jeusfeld, M.A.; Hoppenbrouwers, J.

    From the standpoint of satisfying human's information needs, the current digital library (DL) systems suffer from the following two shortcomings: (i) inadequate high-level cognition support; (ii) inadequate knowledge sharing facilities. In this article, we introduce a two-layered digital library

  3. SHAMSI, 48 group cross-section library for fusion nucleonics analysis

    International Nuclear Information System (INIS)

    Ponti, C.; Abbas, Tayyab.

    1982-01-01

    A P 3 48 group coupled neutron gamma-ray (34 N - 14 G) cross-section library is produced and validated for neutronic studies in fusion reactor blanket/shield. This report describes the library content, the procedure adopted and the results of the calculations performed for testing the cross sections

  4. A program for calculating group constants on the basis of libraries of evaluated neutron data

    International Nuclear Information System (INIS)

    Sinitsa, V.V.

    1987-01-01

    The GRUKON program is designed for processing libraries of evaluated neutron data into group and fine-group (having some 300 groups) microscopic constants. In structure it is a package of applications programs with three basic components: a monitor, a command language and a library of functional modules. The first operative version of the package was restricted to obtaining mid-group non-block cross-sections from evaluated neutron data libraries in the ENDF/B format. This was then used to process other libraries. In the next two versions, cross-section table conversion modules and self-shielding factor calculation modules, respectively, were added to the functions already in the package. Currently, a fourth version of the GRUKON applications program package, for calculation of sub-group parameters, is under preparation. (author)

  5. Advanced Neutron Source Cross Section Libraries (ANSL-V): ENDF/B-V based multigroup cross-section libraries for advanced neutron source (ANS) reactor studies

    International Nuclear Information System (INIS)

    Ford, W.E. III; Arwood, J.W.; Greene, N.M.; Moses, D.L.; Petrie, L.M.; Primm, R.T. III; Slater, C.O.; Westfall, R.M.; Wright, R.Q.

    1990-09-01

    Pseudo-problem-independent, multigroup cross-section libraries were generated to support Advanced Neutron Source (ANS) Reactor design studies. The ANS is a proposed reactor which would be fueled with highly enriched uranium and cooled with heavy water. The libraries, designated ANSL-V (Advanced Neutron Source Cross Section Libraries based on ENDF/B-V), are data bases in AMPX master format for subsequent generation of problem-dependent cross-sections for use with codes such as KENO, ANISN, XSDRNPM, VENTURE, DOT, DORT, TORT, and MORSE. Included in ANSL-V are 99-group and 39-group neutron, 39-neutron-group 44-gamma-ray-group secondary gamma-ray production (SGRP), 44-group gamma-ray interaction (GRI), and coupled, 39-neutron group 44-gamma-ray group (CNG) cross-section libraries. The neutron and SGRP libraries were generated primarily from ENDF/B-V data; the GRI library was generated from DLC-99/HUGO data, which is recognized as the ENDF/B-V photon interaction data. Modules from the AMPX and NJOY systems were used to process the multigroup data. Validity of selected data from the fine- and broad-group neutron libraries was satisfactorily tested in performance parameter calculations

  6. Application of Data Mining in Library-Based Personalized Learning

    Directory of Open Access Journals (Sweden)

    Lin Luo

    2017-12-01

    Full Text Available this paper expounds to mine up data with the DBSCAN algorithm in order to help teachers and students find which books they expect in the sea of library. In the first place, the model that DBSCAN algorithm applies in library data miner is proposed, followed by the DBSCAN algorithm improved on demands. In the end, an experiment is cited herein to validate this algorithm. The results show that the book price and the inventory level in the library produce a less impact on the resultant aggregation than the classification of books and the frequency of book borrowings. Library procurers should therefore purchase and subscribe data based on the results from cluster analysis thereby to improve hierarchies and structure distribution of library resources, forging on the library resources to be more scientific and reasonable, while it is also conducive to arousing readers' borrowing interest.

  7. Evaluation of computer-based library services at Kenneth Dike ...

    African Journals Online (AJOL)

    This study evaluated computer-based library services/routines at Kenneth Dike Library, University of Ibadan. Four research questions were developed and answered. A survey research design was adopted; using questionnaire as the instrument for data collection. A total of 200 respondents randomly selected from 10 ...

  8. Mixture-based combinatorial libraries from small individual peptide libraries: a case study on α1-antitrypsin deficiency.

    Science.gov (United States)

    Chang, Yi-Pin; Chu, Yen-Ho

    2014-05-16

    The design, synthesis and screening of diversity-oriented peptide libraries using a "libraries from libraries" strategy for the development of inhibitors of α1-antitrypsin deficiency are described. The major buttress of the biochemical approach presented here is the use of well-established solid-phase split-and-mix method for the generation of mixture-based libraries. The combinatorial technique iterative deconvolution was employed for library screening. While molecular diversity is the general consideration of combinatorial libraries, exquisite design through systematic screening of small individual libraries is a prerequisite for effective library screening and can avoid potential problems in some cases. This review will also illustrate how large peptide libraries were designed, as well as how a conformation-sensitive assay was developed based on the mechanism of the conformational disease. Finally, the combinatorially selected peptide inhibitor capable of blocking abnormal protein aggregation will be characterized by biophysical, cellular and computational methods.

  9. CSRL-V ENDF/B-V 227-group neutron cross-section library and its application to thermal-reactor and criticality safety benchmarks

    International Nuclear Information System (INIS)

    Ford, W.E. III; Diggs, B.R.; Knight, J.R.; Greene, N.M.; Petrie, L.M.; Webster, C.C.; Westfall, R.M.; Wright, R.Q.; Williams, M.L.

    1982-01-01

    Characteristics and contents of the CSRL-V (Criticality Safety Reference Library based on ENDF/B-V data) 227-neutron-group AMPX master and pointwise cross-section libraries are described. Results obtained in using CSRL-V to calculate performance parameters of selected thermal reactor and criticality safety benchmarks are discussed

  10. [Progress in the spectral library based protein identification strategy].

    Science.gov (United States)

    Yu, Derui; Ma, Jie; Xie, Zengyan; Bai, Mingze; Zhu, Yunping; Shu, Kunxian

    2018-04-25

    Exponential growth of the mass spectrometry (MS) data is exhibited when the mass spectrometry-based proteomics has been developing rapidly. It is a great challenge to develop some quick, accurate and repeatable methods to identify peptides and proteins. Nowadays, the spectral library searching has become a mature strategy for tandem mass spectra based proteins identification in proteomics, which searches the experiment spectra against a collection of confidently identified MS/MS spectra that have been observed previously, and fully utilizes the abundance in the spectrum, peaks from non-canonical fragment ions, and other features. This review provides an overview of the implement of spectral library search strategy, and two key steps, spectral library construction and spectral library searching comprehensively, and discusses the progress and challenge of the library search strategy.

  11. Evidence Based Management as a Tool for Special Libraries

    Directory of Open Access Journals (Sweden)

    Bill Fisher

    2007-12-01

    Full Text Available Objective ‐ To examine the evidence based management literature, as an example of evidence based practice, and determine how applicable evidence based management might be in the special library environment. Methods ‐ Recent general management literature and the subject‐focused literature of evidence based management were reviewed; likewise recent library/information science management literature and the subject‐focused literature of evidence based librarianshipwere reviewed to identify relevant examples of the introduction and use of evidence based practice in organizations. Searches were conducted in major business/management databases, major library/information science databases, and relevant Web sites, blogs and wikis. Citation searches on key articles and follow‐up searches on cited references were also conducted. Analysis of the retrieved literature was conducted to find similarities and/or differences between the management literature and the library/information scienceliterature, especially as it related to special libraries.Results ‐ The barriers to introducing evidence based management into most organizations were found to apply to many special libraries and are similar to issues involved with evidence based practice in librarianship in general. Despite these barriers, a set of resources to assist special librarians in accessing research‐based information to help them use principles of evidence based management is identified.Conclusion ‐ While most special librarians are faced with a number of barriers to using evidence based management, resources do exist to help overcome these obstacles.

  12. ZZ COVFILS, 30-Group Covariance Library from ENDF/B-5 for Sensitivity Studies

    International Nuclear Information System (INIS)

    Muir, D.W.

    1997-01-01

    1 - Description of program or function: Format: ENDB/F; Number of groups: 30-Group Covariance Library; Nuclides: H-1, B-10, C, O-16, Cr, Fe, Ni, Cu, Pb. Origin: ENDF/B-V. COVFILS is a 30-Group Covariance Library. It contains neutron cross sections, and their uncertainties and correlation in multigroup form. These data can be used, in conjunction with sensitivity information, to estimate the data-related uncertainty in calculated integral quantities such as radiation-damage or heating. 2 - Method of solution: COVFILS was obtained by processing evaluations from ENDF/B-V with ERRORR module of the NJOY nuclear data processing system (LA-9303-M, Vols. 1).The group structure is the Los Alamos 30-group structure which is listed in 'File 1' of each multigroup data set in the library

  13. ERRFILS: a preliminary library of 30-group multigroup covariance data for use in CTR sensitivity studies

    International Nuclear Information System (INIS)

    LaBauve, R.J.; Muir, D.W.

    1978-01-01

    A library of 30-group multigroup covariance data was prepared from preliminary ENDF/B-V data with the NJOY code. Data for Fe, Cr, Ni, 10 B, C, Cu, H, and Pb are included in this library. Reactions include total cross sections, elastic and inelastic scattering cross sections, and the most important absorption cross sections. Typical data from the file are shown. 3 tables

  14. Production and Testing of the VITAMIN-B7 Fine-Group and BUGLE-B7 Broad-Group Coupled Neutron/Gamma Cross-Section Libraries Derived from ENDF/B-VII.0 Nuclear Data

    Energy Technology Data Exchange (ETDEWEB)

    Risner, J. M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wiarda, D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Dunn, M. E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Miller, T. M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Peplow, D. E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Patton, B. W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2011-09-30

    New coupled neutron-gamma cross-section libraries have been developed for use in light water reactor (LWR) shielding applications, including pressure vessel dosimetry calculations. The libraries, which were generated using Evaluated Nuclear Data File/B Version VII Release 0 (ENDF/B-VII.0), use the same fine-group and broad-group energy structures as the VITAMIN-B6 and BUGLE-96 libraries. The processing methodology used to generate both libraries is based on the methods used to develop VITAMIN-B6 and BUGLE-96 and is consistent with ANSI/ANS 6.1.2. The ENDF data were first processed into the fine-group pseudo-problem-independent VITAMIN-B7 library and then collapsed into the broad-group BUGLE-B7 library. The VITAMIN-B7 library contains data for 391 nuclides. This represents a significant increase compared to the VITAMIN-B6 library, which contained data for 120 nuclides. The BUGLE-B7 library contains data for the same nuclides as BUGLE-96, and maintains the same numeric IDs for those nuclides. The broad-group data includes nuclides which are infinitely dilute and group collapsed using a concrete weighting spectrum, as well as nuclides which are self-shielded and group collapsed using weighting spectra representative of important regions of LWRs. The verification and validation of the new libraries includes a set of critical benchmark experiments, a set of regression tests that are used to evaluate multigroup crosssection libraries in the SCALE code system, and three pressure vessel dosimetry benchmarks. Results of these tests confirm that the new libraries are appropriate for use in LWR shielding analyses and meet the requirements of Regulatory Guide 1.190.

  15. Research into the Impact of Facebook as a Library Marketing Tool is Inconclusive. A Review of: Xia, D. Z. (2009. Marketing library services through Facebook groups. Library Management 30(6/7, 469-477.

    Directory of Open Access Journals (Sweden)

    David Herron

    2010-09-01

    Full Text Available Objective – To investigate whether Facebook Groups are useful for library marketing.Design – Content analysis of membership and activity of university library-related Facebook Groups.Setting – Two global Facebook Groups, and the Facebook Groups of two academic libraries in the US (Rutgers University and Indiana University, both with populations in excess of 30 000 students.Subjects – A total of 28 Facebook Groups were analyzed.Methods – Facebook global Groups are open to all users, while Groups based in a network (e.g., a university only allow access for those in the network. Therefore, to collect data, theauthor used personal connections to log on to members’ profiles within university networks.The 26 university Groups were selected by searching Facebook for Groups belonging to the two university networks, using the word ‚library.‛ Groups unrelated to library business were discarded. A total of 11 Groups within the Rutgers network were analyzed. Of these, only one was organized by a librarian; the rest were organized by students. From Indiana, 15 Groups were identified, three of which were organized by librarians.In Table 1 (p. 474, all Groups are listed: 2 global Groups and 26 Groups within the two university networks. The author then visited all Groups, read all posts, and recorded the total number of members; status of each member, divided into faculty, staff and students; dates of first and last post; and discussion activity. The author analyzed group activity by keeping a tally of how often each member participated in discussions, as there was no way to see the number of times a member returned. The author also paid special attention to Groups with a large number of staff and faculty members, to gain information about the efforts of librarians to support or start new Groups.Main Results – There were a total of 652 members in the 26 university Groups (mean number of members was 25, ranging from 2 - 176. The two global

  16. Design and producing of fine-group cross section library HENDL3.0/FG for subcritical system

    International Nuclear Information System (INIS)

    Zou, J.; Zeng, Q.; Xu, D.; Hu, L.; Long, P.

    2012-01-01

    To improve the accuracy of the neutron analyses for subcritical system with thermal fission blanket, a coupled neutron and photon (315 n + 42γ) fine-group cross section library HENDL3.0/FG based on ENDF/B-VII, JEFF3.1 and JENDL3.3 was produced by FDS team. In order to test the availability and reliability of the HENDL3.0/FG data library, shielding and critical safety benchmarks were performed with VisualBUS code. The testing results indicated that the discrepancy between calculation and experimental values of nuclear parameters fell in a reasonable range. It showed that the nuclear data library had accuracy and availability. (authors)

  17. The Internet as a Library-Of-People: For a Cyberethnography of Online Groups

    Directory of Open Access Journals (Sweden)

    Maurizio Teli

    2007-09-01

    Full Text Available The concept "cyberethnography" remains undefined in the social sciences while, at the same time, still overlapping too much with the more well-known concept of "virtual ethnography." The aim of our paper is to remedy this situation by underlining new directions in the ethnographic study of computer mediated settings. To do so, we define cyberspace as computer-mediated contexts intrinsically related to supposed-to-be "real" places. From this point of view the ethnography of online groups is not just the ethnography of the groups online (or the online ethnography of groups, but it is both the ethnography of online and related off-line situations, the ethnography of humans and non-human actors in these related fields. It is hybrid, like a cyborg. In a word, it is a cyberethnography. In the first part of the paper, we discuss linkages between classical ethnography and its cyber developments. In the second part, we ground epistemologically the argument in favor of a robust social concept of "cyborg" drawing mainly from the fields called Science, Technology and Society (STS, and Organization Studies (OS. In the third part, we focus our argument on web-based group issues, using field data from our own research to define this kind of group and propose a metaphor, "the Internet as a library-of-people." This metaphor, which is strictly grounded in the cyborg concept, highlights the cyborgic characteristic of society that arises in research practice. URN: urn:nbn:de:0114-fqs0703338

  18. Fee-based services in sci-tech libraries

    CERN Document Server

    Mount, Ellis

    2013-01-01

    This timely and important book explores how fee-based services have developed in various types of sci-tech libraries. The authoritative contributors focus on the current changing financial aspects of the sci-tech library operation and clarify for the reader how these changes have brought about conditions in which traditional methods of funding are no longer adequate. What new options are open and how they are best being applied in today's sci-tech libraries is fully and clearly explained and illustrated. Topics explored include cost allocation and cost recovery, fees for computer searching, an

  19. Endf/B-VII.0 Based Library for Paragon - 313

    International Nuclear Information System (INIS)

    Huria, H.C.; Kucukboyaci, V.N.; Ouisloumen, M.

    2010-01-01

    A new 70-group library has been generated for the Westinghouse lattice physics code PARAGON using the ENDF/B-VII.0 nuclear data files. The new library retains the major features of the current library, including the number of energy groups and the reduction in the U-238 resonance integral. The upper bound for the up-scattering effects in the new library, however, has been moved to 4.0 eV from 2.1 eV for better MOX fuel predictions. The new library has been used to analyze standard benchmarks and also to compare the measured and predicted parameters for different types of Westinghouse and Combustion Engineering (CE) type operating reactor cores. Results indicate that the new library will not impact the reactivity, power distribution and the temperature coefficient predictions over a wide range of physics design parameters; however, will improve the MOX core predictions. In other words, the ENDF/B-VI.3 and ENDF/B-VII.0 produce similar results for reactor core calculations. (authors)

  20. Optimization of reference library used in content-based medical image retrieval scheme

    International Nuclear Information System (INIS)

    Park, Sang Cheol; Sukthankar, Rahul; Mummert, Lily; Satyanarayanan, Mahadev; Zheng Bin

    2007-01-01

    Building an optimal image reference library is a critical step in developing the interactive computer-aided detection and diagnosis (I-CAD) systems of medical images using content-based image retrieval (CBIR) schemes. In this study, the authors conducted two experiments to investigate (1) the relationship between I-CAD performance and size of reference library and (2) a new reference selection strategy to optimize the library and improve I-CAD performance. The authors assembled a reference library that includes 3153 regions of interest (ROI) depicting either malignant masses (1592) or CAD-cued false-positive regions (1561) and an independent testing data set including 200 masses and 200 false-positive regions. A CBIR scheme using a distance-weighted K-nearest neighbor algorithm is applied to retrieve references that are considered similar to the testing sample from the library. The area under receiver operating characteristic curve (A z ) is used as an index to evaluate the I-CAD performance. In the first experiment, the authors systematically increased reference library size and tested I-CAD performance. The result indicates that scheme performance improves initially from A z =0.715 to 0.874 and then plateaus when the library size reaches approximately half of its maximum capacity. In the second experiment, based on the hypothesis that a ROI should be removed if it performs poorly compared to a group of similar ROIs in a large and diverse reference library, the authors applied a new strategy to identify 'poorly effective' references. By removing 174 identified ROIs from the reference library, I-CAD performance significantly increases to A z =0.914 (p<0.01). The study demonstrates that increasing reference library size and removing poorly effective references can significantly improve I-CAD performance

  1. 12G: code for conversion of isotope-ordered cross-section libraries into group-ordered cross-section libraries

    International Nuclear Information System (INIS)

    Resnik, W.M. II; Bosler, G.E.

    1977-09-01

    Many current reactor physics codes accept cross-section libraries in an isotope-ordered form, convert them with internal preprocessing routines to a group-ordered form, and then perform calculations using these group-ordered data. Occasionally, because of storage and time limitations, the preprocessing routines in these codes cannot convert very large multigroup isotope-ordered libraries. For this reason, the I2G code, i.e., ISOTXS to GRUPXS, was written to convert externally isotope-ordered cross section libraries in the standard file format called ISOTXS to group-ordered libraries in the standard format called GRUPXS. This code uses standardized multilevel data management routines which establish a strategy for the efficient conversion of large libraries. The I2G code is exportable contingent on access to, and an intimate familiarization with, the multilevel routines. These routines are machine dependent, and therefore must be provided by the importing facility. 6 figures, 3 tables

  2. Comparison of CASMO and NESSEL few group cross section libraries and their usage in DYN3D

    International Nuclear Information System (INIS)

    Kuchin, A.; Ovdiyenko, Y.; Loetsch, T.

    2007-01-01

    This work presents comparative analysis of two group diffusion cross section libraries which were generated by NESSEL-4 and CASMO-4 lattice codes. Diffusion parameters were calculated for VVER-1000 fuel assemblies with stainless steel spacing grids and guiding tubes. These cross section sets were introduced into reactor core code DYN3D and tested on the base of real reactor core states. In this case operation data of the first three fuel cycles of 6-th unit of Zaporizhzhya NPP were used

  3. Special Collections in ARL Libraries: A Discussion Report from the ARL Working Group on Special Collections

    Science.gov (United States)

    Association of Research Libraries, 2009

    2009-01-01

    This discussion report identifies key issues in the management of special collections material in the 21st century. The report uses a broad definition of "special collections," which encompasses distinctive material in all media and attendant library services. The group's main focus was on 19th- and 20th-century materials, including…

  4. Library

    OpenAIRE

    Dulaney, Ronald E. Jr.

    1997-01-01

    This study began with the desire to design a public town library of the future and became a search for an inkling of what is essential to Architecture. It is murky and full of contradictions. It asks more than it proposes, and the traces of its windings are better ordered through collage than logical synthesis. This study is neither a thesis nor a synthesis. When drawing out the measure of this study it may be beneficial to state what it attempts to place at the ...

  5. Structure-Based Virtual Screening of Commercially Available Compound Libraries.

    Science.gov (United States)

    Kireev, Dmitri

    2016-01-01

    Virtual screening (VS) is an efficient hit-finding tool. Its distinctive strength is that it allows one to screen compound libraries that are not available in the lab. Moreover, structure-based (SB) VS also enables an understanding of how the hit compounds bind the protein target, thus laying ground work for the rational hit-to-lead progression. SBVS requires a very limited experimental effort and is particularly well suited for academic labs and small biotech companies that, unlike pharmaceutical companies, do not have physical access to quality small-molecule libraries. Here, we describe SBVS of commercial compound libraries for Mer kinase inhibitors. The screening protocol relies on the docking algorithm Glide complemented by a post-docking filter based on structural protein-ligand interaction fingerprints (SPLIF).

  6. The TENDL neutron data library and the TEND1038 38-group neutron constant system

    International Nuclear Information System (INIS)

    Abramovich, S.N.; Gorelov, V.P.; Gorshikhin, A.A.; Grebennikov, A.N.; Il'in, V.N.; Krut'ko, N.A.; Farafontov, G.G.

    2002-01-01

    The library contains neutron data for 103 nuclei - i.e. for 38 actinide nuclei (from 232 Th to 249 Cm), 26 fission fragment nuclei and 39 nuclei in structural and technological materials. The 38-group constants were obtained from TENDL. The high-energy group boundary is 20 MeV. The energy range below 1.2 eV contains 11 groups. Temperature and resonance effects were taken into account. The delayed neutron parameters for 6 groups and the yields of 40 fission fragments were obtained (light and heavy, stable and non-stable). The fast neutron features of spherical critical assemblies were calculated using constants from TEND1038. (author)

  7. Views From the Pacific--Military Base Hospital Libraries in Hawaii and Guam.

    Science.gov (United States)

    Stephenson, Priscilla L; Trafford, Mabel A; Hadley, Alice E

    2016-01-01

    Hospital libraries serving military bases offer a different perspective on library services. Two libraries located on islands in the Pacific Ocean provide services to active duty service men and women, including those deployed to other regions of the world. In addition, these hospital libraries serve service members' families living on the base, and often citizens from the surrounding communities.

  8. CSRL-V: processed ENDF/B-V 227-neutron-group and pointwise cross-section libraries for criticality safety, reactor, and shielding studies

    International Nuclear Information System (INIS)

    Ford, W.E. III; Diggs, B.R.; Petrie, L.M.; Webster, C.C.; Westfall, R.M.

    1982-01-01

    A P 3 227-neutron-group cross-section library has been processed for the subsequent generation of problem-dependent fine- or broad-group cross sections for a broad range of applications, including shipping cask calculations, general criticality safety analyses, and reactor core and shielding analyses. The energy group structure covers the range 10 -5 eV - 20 MeV, including 79 thermal groups below 3 eV. The 129-material library includes processed data for all materials in the ENDF/B-V General Purpose File, several data sets prepared from LENDL data, hydrogen with water- and polyethyelene-bound thermal kernels, deuterium with C 2 O-bound thermal kernels, carbon with a graphite thermal kernel, a special 1/V data set, and a dose factor data set. The library, which is in AMPX master format, is designated CSRL-V (Criticality Safety Reference Library based on ENDF/B-V data). Also included in CSRL-V is a pointwise total, fission, elastic scattering, and (n,γ) cross-section library containing data sets for all ENDF/B-V resonance materials. Data in the pointwise library were processed with the infinite dilute approximation at a temperature of 296 0 K

  9. Experience in developing and using the VITAMIN-C 171-neutron, 36-gamma-ray group cross-section library

    International Nuclear Information System (INIS)

    Roussin, R.W.; Weisbin, C.R.; White, J.E.; Wright, R.Q.; Greene, N.M.; Ford, W.E. III; Wright, J.B.; Diggs, B.R.

    1978-01-01

    The Department of Energy (DOE) Division of Magnetic Fusion Energy (DMFE) and Reactor Research and Technology (DRRT) jointly sponsored the development of a coupled, fine-group cross-section library. The 171-neutron, 36-gamma-ray group library is intended to be applicable to fusion reactor neutronics and LMFBR core and shield analysis. Versions of the library are available from the Radiation Shielding Information Center (RSIC) at Oak Ridge National Laboratory in both AMPX and CCCC formats. Computer codes for energy group collapsing, interpolation on Bondarenko factors for resonance self-shielding and temperature corrections, and various other useful data manipulations are available. The experience gained in the utilization of this library is discussed. Indications are that this venture, which is designed to allow users to derive problem-dependent cross sections from a fine-group master library, has been a success

  10. Evidence-based Practice in libraries - Principles and discussions

    DEFF Research Database (Denmark)

    Johannsen, Carl Gustav

    2012-01-01

    The article examines problems concerning the introduction and future implementation of evidence-based practice (EBP) in libraries. It includes important conceptual distinctions and definitions, and it reviews the more controversial aspects of EBP, primarely based on experiences from Denmark. The ....... The purpose of the article is both to qualify existing scepticism and reservations and - maybe - to clarify misunderstandings and objections through the presentation of arguments and data....

  11. School Library Media Specialists Inform Technology Preparation of Library Science Students: An Evidence-Based Discussion

    Science.gov (United States)

    Snyder, Donna L.; Miller, Andrea L.

    2009-01-01

    What is the relative importance of current and emerging technologies in school library media programs? In order to answer this question, in Fall 2007 the authors administered a survey to 1,053 school library media specialists (SLMSs) throughout the state of Pennsylvania. As a part of the MSLS degree with Library Science K-12 certification, Clarion…

  12. BUGLE-96: A revised multigroup cross section library for LWR applications based on ENDF/B-VI Release 3

    International Nuclear Information System (INIS)

    White, J.E.; Ingersoll, D.T.; Slater, C.O.; Roussin, R.W.

    1996-01-01

    A revised multigroup cross-section library based ON ENDF/B-VI Release 3 has been produced for light water reactor shielding and reactor pressure vessel dosimetry applications. This new broad-group library, which is designated BUGLE-96, represents an improvement over the BUGLE-93 library released in February 1994 and is expected to replace te BUGLE-93 data. The cross-section processing methodology is the same as that used for producing BUGLE-93 and is consistent with ANSI/ANS 6.1.2. As an added feature, cross-section sets having upscatter data for four thermal neutron groups are included in the BUGLE-96 package available from the Radiation Shielding Information Center. The upscattering data should improve the application of this library to the calculation of more accurate thermal fluences, although more computer time will be required. The incorporation of feedback from users has resulted in a data library that addresses a wider spectrum of user needs

  13. ZZ BOREHOLE-EB6.8-MG, multi group cross-section library for deterministic and Monte Carlo codes

    International Nuclear Information System (INIS)

    Kodeli, Ivo; Aldama, Daniel L.; Leege, Piet F.A. de; Legrady, David; Hoogenboom, J. Eduard

    2007-01-01

    1 - Description: Format: MATXS and ACE; Number of groups: 175 neutron, 45 gamma-ray; Nuclides: H-1, C-12, O-16, Na-23, Mg-nat, Al-27, Si-28, -29, -30, S-nat, Cl-35, -37, K-nat, Ca-nat, Mn-55, Fe-54, -56, -57, -58, I-127, W-nat. Origin: ENDF/B-VI.8; Weighting spectrum: Fission and fusion peak at high energies and a 1/E + thermal Maxwellian extension at low energies. The following materials/nuclides are included in the library: H-1, C-12, O-16, Na-23, Mg-nat, Al-27, Si-28, -29, -30, S-nat, Cl-35, -37, K-nat, Ca-nat, Fe-54, -56, -57, -58, Mn-55, I-127, W-nat. ZZ-BOREHOLE-EB6.8-MG is a multigroup cross section library for deterministic (DOORS, DANTSYS) and Monte Carlo (MCNP) transport codes developed for the oil well logging applications. The library is based on the ENDF/B-VI.8 evaluation and was processed by the NJOY-99 code. The cross sections are given in the 175 neutron and 45 gamma ray group structure. The MATXS format library can be directly used in TRANSX code to prepare the multigroup self-shielded cross sections for deterministic discrete ordinates codes like DOORS and DANTSYS. The data provided in the GROUPR and GAMINR format were converted to the MCNP ACE format by the NSLINK, SCALE and CRSRD codes. IAEA1398/03: Multigroup cross section data for Mn-55 were added in TRANSX format

  14. User Perceptions of the Library's Web Pages: A Focus Group Study at Texas A&M University.

    Science.gov (United States)

    Crowley, Gwyneth H.; Leffel, Rob; Ramirez, Diana; Hart, Judith L.; Armstrong, Tommy S., II

    2002-01-01

    This focus group study explored library patrons' opinions about Texas A&M library's Web pages. Discusses information seeking behavior which indicated that patrons are confused when trying to navigate the Public Access Menu and suggests the need for a more intuitive interface. (Author/LRW)

  15. The generation, validation and testing of a coupled 219-group neutron 36-group gamma ray AMPX-II library

    International Nuclear Information System (INIS)

    Panini, G.C.; Siciliano, F.; Lioi, A.

    1987-01-01

    The main characteristics of a P 3 coupled 219-group neutron 36-group gamma-ray library in the AMPX-II Master Interface Format obtained processing ENDF/B-IV data by means of various AMPX-II System modules are presented in this note both for the more reprocessing aspects and features of the generated component files-neutrons, photon and secondary gamma-ray production cross sections. As far as the neutron data are concerned there is the avaibility of 186 data sets regarding most significant fission products. Results of the additional validation of the neutron data pertaining to eighteen benchmark experiments are also given. Some calculational tests on both neutron and coupled data emphasize the important role of the secondary gamma-ray data in nuclear criticality safety calculations

  16. ROSFOND based heating-damage cross sections sub-library: Preliminary uncertainty assessment

    International Nuclear Information System (INIS)

    Sinitsa, V.V.

    2016-01-01

    The accuracy of radiation damage calculations for the most important LWR component, the reactor pressure vessel (RPV), directly linked with the RPV End-of-Life (EoL) prediction which is in its turn connected with fundamental nuclear safety aspects and relevant economic impacts. In this connection, for nearly ten years the ENEA-Bologna Nuclear Data Group conducts the nuclear data processing and validation activities addressed to update the specialized broad-group coupled neutron/photon working cross section libraries for shielding and radiation damage calculations through NJOY and Bologna revised version of SCAMPI data processing systems. A number of working group-wise data libraries has been prepared and transferred to the ENEA Data Bank for dissemination. Several years ago the NRC ”Kurchatov Institute” has reset the GRUCON project, originally designed to provide group constants for fast nuclear reactor calculations [12], with aim to expand its application area and to use in the WWER safety tasks, in particular, in the RPV radiation damage analyses. By means of updated GRUCON and NJOY-99 processing codes, and calculation procedure, developed in the NDG of ENEA Bologna, a sample of kerma&damage energy point-wise data sub-libraries from different evaluated data libraries has been generated. On the base of this sample, the quantitative assessment of kerma/dpa data precision in the RPV calculations is obtained

  17. Speech-Based Information Retrieval for Digital Libraries

    National Research Council Canada - National Science Library

    Oard, Douglas W

    1997-01-01

    Libraries and archives collect recorded speech and multimedia objects that contain recorded speech, and such material may comprise a substantial portion of the collection in future digital libraries...

  18. Salary survey of the Medical Library Group of Southern California and Arizona.

    Science.gov (United States)

    Smith, J L; Connolly, B F; Davis, M; Graham, E; Wheeler, S

    1984-01-01

    The 1982 salary survey of the Medical Library Group of Southern California and Arizona (MLGSCA) indicates that 211 health sciences librarians in Southern California and Arizona earned a mean annual salary of $20,910 for 1982. Data analysis shows a positive correlation between salary and educational level. Other factors found to affect salary were job history, number of positions held, MLA certification, and professional responsibility. Age, gender, and MLA certification did not have a consistent positive correlation with salary. Results indicate that the salaries of hospital librarians are, on the average, roughly comparable to those of academic librarians in Southern California and Arizona. PMID:6743878

  19. Production and testing of the VITAMIN-B6 fine-group and the BUGLE-93 broad-group neutron/photon cross-section libraries derived from ENDF/B-VI nuclear data

    International Nuclear Information System (INIS)

    Ingersoll, D.T.; White, J.E.; Wright, R.Q.; Hunter, H.T.; Slater, C.O.; Greene, N.M.; MacFarlane, R.E.

    1993-01-01

    A new multigroup cross-section library based on ENDF/B-VI data has been produced and tested for light water reactor shielding and reactor pressure vessel dosimetry applications. The broad-group library is designated BUGLE-93. The processing methodology is consistent with ANSI/ANS 6.1.2, since the ENDF data were first processed into a fine-group, ''pseudo problem-independent'' format and then collapsed into the final broad-group format. The fine-group library is designated VITAMIN-B6. An extensive integral data testing effort was also performed. In general, results using the new data show significant improvements relative to earlier ENDF data

  20. Template-based combinatorial enumeration of virtual compound libraries for lipids.

    Science.gov (United States)

    Sud, Manish; Fahy, Eoin; Subramaniam, Shankar

    2012-09-25

    A variety of software packages are available for the combinatorial enumeration of virtual libraries for small molecules, starting from specifications of core scaffolds with attachments points and lists of R-groups as SMILES or SD files. Although SD files include atomic coordinates for core scaffolds and R-groups, it is not possible to control 2-dimensional (2D) layout of the enumerated structures generated for virtual compound libraries because different packages generate different 2D representations for the same structure. We have developed a software package called LipidMapsTools for the template-based combinatorial enumeration of virtual compound libraries for lipids. Virtual libraries are enumerated for the specified lipid abbreviations using matching lists of pre-defined templates and chain abbreviations, instead of core scaffolds and lists of R-groups provided by the user. 2D structures of the enumerated lipids are drawn in a specific and consistent fashion adhering to the framework for representing lipid structures proposed by the LIPID MAPS consortium. LipidMapsTools is lightweight, relatively fast and contains no external dependencies. It is an open source package and freely available under the terms of the modified BSD license.

  1. Use of internet library based services by the students of Imo State ...

    African Journals Online (AJOL)

    Findings show that students utilizes internet based library services in their academic work, for their intellectual development as well as in communicating to their lecturers and other relations on their day to day information needs. It is recommended that University libraries should provide and offer internet based library ...

  2. Activity-Based Costing in User Services of an Academic Library.

    Science.gov (United States)

    Ellis-Newman, Jennifer

    2003-01-01

    The rationale for using Activity-Based Costing (ABC) in a library is to allocate indirect costs to products and services based on the factors that most influence them. This paper discusses the benefits of ABC to library managers and explains the steps involved in implementing ABC in the user services area of an Australian academic library.…

  3. A Web-Based Electronic Book (e-book) Library: The netLibrary Model.

    Science.gov (United States)

    Connaway, Lynn Silipigni

    2001-01-01

    Identifies elements that are important for academic libraries to use in evaluating electronic books, including content; acquisition and collection development; software and hardware standards and protocols; digital rights management; access; archiving; privacy; the market and pricing; and enhancements and ideal features. Describes netLibrary, a…

  4. ORIGEN2 libraries based on JENDL-3.2 for LWR-MOX fuels

    Energy Technology Data Exchange (ETDEWEB)

    Suyama, Kenya; Katakura, Jun-ichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Onoue, Masaaki; Matsumoto, Hideki [Mitsubishi Heavy Industries Ltd., Tokyo (Japan); Sasahara, Akihiro [Central Research Inst. of Electric Power Industry, Tokyo (Japan)

    2000-11-01

    A set of ORIGEN2 libraries for LWR MOX fuels was developed based on JENDL-3.2. The libraries were compiled with SWAT using the specification of MOX fuels that will be used in nuclear power reactors in Japan. The verification of the libraries were performed by the analyses of post irradiation examinations for the fuels from European PWR. By the analysis of PIE data from PWR in United States, the comparison was made between calculation and experimental results in the case of that parameters for making the libraries are different from irradiation conditions. These new libraries for LWR MOX fuels are packaged in ORLIBJ32, the libraries released in 1999. (author)

  5. Development of a new nuclear data library based on ROOT

    Directory of Open Access Journals (Sweden)

    Park Tae-Sun

    2017-01-01

    Full Text Available We develop a new C++ nuclear data library for the Evaluated Nuclear Data File (ENDF data, which we refer to as TNudy. Main motivation of the development is to provide systematic, powerful and intuitive interfaces and functionalities for browsing, visualizing and manipulating the detailed information embodied in the ENDF. To achieve this aim efficiently, the TNudy project is based on the ROOT system. TNudy is still in the stage of development, and the current status and future plans will be presented.

  6. MCNP4c JEFF-3.1 Based Libraries. Eccolib-Jeff-3.1 libraries

    International Nuclear Information System (INIS)

    Sublet, J.Ch.

    2006-01-01

    Continuous-energy and multi-temperatures MCNP Ace types libraries, derived from the Joint European Fusion-Fission JEFF-3.1 evaluations, have been generated using the NJOY-99.111 processing code system. They include the continuous-energy neutron JEFF-3.1/General Purpose, JEFF-3.1/Activation-Dosimetry and thermal S(α,β) JEFF-3.1/Thermal libraries and data tables. The processing steps and features are explained together with the Quality Assurance processes and records linked to the generation of such multipurpose libraries. (author)

  7. Information about AER WG a on improvement, extension and validation of parametrized few-group libraries for VVER 440 and VVER 1000

    International Nuclear Information System (INIS)

    Mikolas, P.

    2009-01-01

    Joint AER Working Group A on 'Improvement, extension and validation of parameterized few-group libraries for VVER-440 and VVER-1000' and AER Working group B on 'Core design' eighteenth meeting was hosted by Skoda JS a.s. in Plzen (Czech Republic) during the period of 4 to 6 May 2009. There were present altogether 16 participants from 6 member organizations and 13 presentations were read. Objectives of the meeting of WG A are: Issues connected with spectral calculations and few-groups libraries preparation, their accuracy and validation. Presentations were devoted to some aspects of few group libraries preparations and to the benchmark dealing with VVER-440 follower modeling in calculations. Gy. Hegyi gave some new information about NURESIM-NURISP EU project (ZR-6), R. Zajac spoke about the development of data libraries for codes BIPR-7 and PERMAK, P. Darilek compared FA's with Gd during burning process and Yu. Bilodid described further development of plutonium-based burnup history modeling in DYN3D burnup calculations. G. Hordosy presented results of control rod follower induced local power peaking computational benchmark and J. Svarny described Monte Carlo VVER-440 control rod follower benchmark computations. Future activities are also shortly described in the end of the paper. (author)

  8. Development of fine-group (315n/42γ) cross section library ENDL3.0/FG for fusion-fission hybrid systems

    International Nuclear Information System (INIS)

    Zeng Qin; Zou Jun; Xu Dezhen; Jiang Jieqiong; Wang Minghuang; Wu Yican; Qiu Yuefeng; Chen Zhong; Chen Yan

    2011-01-01

    To improve the accuracy of the neutron analyses for subcritical systems with thermal fission blanket, a coupled neutron and photon (315 n + 42γ) fine-group cross section library HENDL3.0/FG based on ENDF/B-Ⅶ. 0 has been produced by FDS team. In order to test the availability and reliability of the HENDL3.0/FG data library, shielding and critical safety benchmarks were performed with VisualBUS code. The testing results indicated that the discrepancy between calculation and experimental values of nuclear parameters fell in a reasonable range. (authors)

  9. WIMS-IJSO - An extended version of the WIMS group constant library

    International Nuclear Information System (INIS)

    Trkov, A.; Perdan, A.

    1982-11-01

    WIMS-IJSO is a preliminary extended version of the WIMS library as supplied with the CDC version of the S-WIMS-code. It is a result of the feasibility study of the possibility to update and extend the WIMS library. In the course of its preparation valuable experience was gained in understanding the definitions, the conventions and the structure of the WIMS library. This experience will be used in the preparation of an extended WIMS library for some materials from carefully chosen evaluated data. The library as supplied with the WIMS-D4 package will be used as the basis. The materials added to the library had been tested in reactor calculations and their performance was found to be satisfactory. The aim of releasing the preliminary version of the WIMS library is to allow different users to apply the data to various problems

  10. Cytogenetical anchoring of sheep linkage map and syntenic groups using a sheep BAC library

    Directory of Open Access Journals (Sweden)

    Cribiu Edmond-Paul

    2000-07-01

    Full Text Available Abstract In order to simultaneously integrate linkage and syntenic groups to the ovine chromosomal map, a sheep bacterial artificial chromosome (BAC library was screened with previously assigned microsatellites using a sheep-hamster hybrid panel and genetic linkage. Thirty-three BACs were obtained, fluorescently labelled and hybridised on sheep-goat hybrid metaphases (2n = 57. This study allowed us, (i, to anchor all linkage groups on sheep chromosomes, (ii, to give information on the probable position of the centromere on the linkage map for the centromeric chromosomes, (iii, to contradict the previous orientation of the ovine × linkage group by the mapping of BMS1008 on OARXq38. Concerning our somatic cell hybrid panel, this study resulted in the assignment of all the previously unassigned groups to ovine chromosomes and a complete characterisation of the hybrid panel. In addition, since hybridisations were performed on a sheep-goat hybrid, new marker/anchoring points were added to the caprine cytogenetic map.

  11. AER working group A on improvement extension and validation of parametrized few-group libraries for VVER-440 and VVER-1000

    International Nuclear Information System (INIS)

    Svarny, J.

    1998-01-01

    The AER Working Groups A and B held its sixth meeting at SKODA JS, Plzen in April 28 and 29, 1998. There were altogether 13 participants from 6 member organizations. The list of participants and the list of papers are attached. Main topics of the meeting were: A few-group cross-section library preparation methodology (standard few-group libraries, kinetics parameters, SPND signal interpretation parametrization) and its validation; Participation on intercomparisons of spectral codes (spectral codes benchmark); of kinetics parameters calculations (kinetics parameters benchmark). (author)

  12. The use of mobile technology in health libraries: a summary of a UK-based survey.

    Science.gov (United States)

    Chamberlain, David; Elcock, Martin; Puligari, Preeti

    2015-12-01

    Health libraries have changed over the past fifteen years in the format of the information they provide. This is driven by developments in technology. To conduct a survey of NHS health libraries in the United Kingdom in order to summarise how mobile technologies are being used, how they are promoted and how they are delivered, highlighting good practice and solutions to issues. An online survey was carried out in 2013 and sent to academic and NHS web-based discussion lists. There were 199 responses. Main replies were from large Acute Hospital Trusts. Only 18% of respondents had conducted research into use of mobile technology (MT) within their Trust. Forty per cent of Trusts offered clinical point of care tools, 29% mobile catalogues, and 30% had mobile enabled web sites. Libraries utilised third-party partnerships rather than develop their own applications or tools. Seventy per cent of Trusts promoted new MT services via e-mail. Network restrictions were the main barrier to development as well as finance and expertise. Uptake and development of MT is sporadic and driven by individuals. There is an opportunity for collaboration and sharing resources and expertise. There are benefits to adopting user-friendly resources. © 2015 Health Libraries Group.

  13. Comparison of CASMO and NESSEL few group cross section libraries and their usage in DYN3D

    International Nuclear Information System (INIS)

    Kuchin, A.; Ovdiyenko, Y.; Loetsch, T.

    2007-01-01

    This work presents comparative analysis of two group diffusion cross sections libraries which were generated by NESSEL-4 and CASMO-4 lattice codes. Diffusion parameters were calculated for WWER-1000 fuel assemblies with stainless steel spacing grids and guiding tubes. These cross section sets were introduced into reactor core code DYN3D and tested on the base of real reactor core states. In this case operation data of the first three fuel cycles of sixth unit of Zaporizhzhya NPP were used. The work was performed in the framework of the order BMU SR 2511 - 862 500/09, UA-2575. The report describes the opinion and view of the contractor - TUV ENERGIE CONSULT - and does not necessarily represent the opinion of the ordering party - Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (Authors)

  14. A problem-based learning curriculum in transition: the emerging role of the library.

    Science.gov (United States)

    Eldredge, J D

    1993-07-01

    This case study describes library education programs that serve the University of New Mexico School of Medicine, known for its innovative problem-based learning (PBL) curricular track. The paper outlines the specific library instruction techniques that are integrated into the curriculum. The adaptation of library instruction to a PBL mode of medical education, including the use of case studies, is discussed in detail. Also addressed are the planning processes for the new PBL curriculum scheduled for implementation in 1993, including the activities of library faculty and staff and the probable new role of the library in the new curriculum.

  15. America's Star Libraries

    Science.gov (United States)

    Lyons, Ray; Lance, Keith Curry

    2009-01-01

    "Library Journal"'s new national rating of public libraries, the "LJ" Index of Public Library Service, identifies 256 "star" libraries. It rates 7,115 public libraries. The top libraries in each group get five, four, or three Michelin guide-like stars. All included libraries, stars or not, can use their scores to learn from their peers and improve…

  16. Survey of group data libraries for use of the DYN3D program for WWER type reactors

    International Nuclear Information System (INIS)

    Mittag, S.

    1994-06-01

    So-called few-group neutron data have to be used as input data in core models (such as DYN3D) calculating the reactor behaviour. A survey is given of qualified data libraries for the reactor cores of Russian VVER. The information about primary data used in group data generation and the accuracy reached by the cell codes is compiled in tables. To assess the quality of the data, comparisons have been made between measured and calculated reactor parameters. The information available does not show significant differences concerning the quality of the data libraries. (orig.) [de

  17. Cloud-based services for your library a LITA guide

    CERN Document Server

    Mitchell, Erik T

    2013-01-01

    By exploring specific examples of cloud computing and virtualization, this book allows libraries considering cloud computing to start their exploration of these systems with a more informed perspective.

  18. Security of Heterogeneous Content in Cloud Based Library Information Systems Using an Ontology Based Approach

    Directory of Open Access Journals (Sweden)

    Mihai DOINEA

    2014-01-01

    Full Text Available As in any domain that involves the use of software, the library information systems take advantages of cloud computing. The paper highlights the main aspect of cloud based systems, describing some public solutions provided by the most important players on the market. Topics related to content security in cloud based services are tackled in order to emphasize the requirements that must be met by these types of systems. A cloud based implementation of an Information Library System is presented and some adjacent tools that are used together with it to provide digital content and metadata links are described. In a cloud based Information Library System security is approached by means of ontologies. Aspects such as content security in terms of digital rights are presented and a methodology for security optimization is proposed.

  19. What Do Stakeholders Know about School Library Programs? Results of a Focus Group Evaluation

    Science.gov (United States)

    Everhart, Nancy

    2014-01-01

    Supporting the "Infrastructure Needs of 21st Century School Library Programs," also known as the Pennsylvania School Library Project, was a one-year project conducted in Pennsylvania to better identify and understand what stakeholders--teachers, administrators, parents, school and community leaders, and education associations--expect…

  20. MICROX-2 cross section library based on ENDF/B-VII

    International Nuclear Information System (INIS)

    Hou, J.; Ivanov, K.; Choi, H.

    2012-01-01

    New cross section libraries of a neutron transport code MICROX-2 have been generated for advanced reactor design and fuel cycle analyses. A total of 386 nuclides were processed, including 10 thermal scattering nuclides, which are available in ENDF/B-VII release 0 nuclear data. The NJOY system and MICROR code were used to process nuclear data and convert them into MICROX-2 format. The energy group structure of the new library was optimized for both the thermal and fast neutron spectrum reactors based on Contributon and Point-wise Cross Section Driven (CPXSD) method, resulting in a total of 1173 energy groups. A series of lattice cell level benchmark calculations have been performed against both experimental measurements and Monte Carlo calculations for the effective/infinite multiplication factor and reaction rate ratios. The results of MICROX-2 calculation with the new library were consistent with those of 15 reference cases. The average errors of the infinite multiplication factor and reaction rate ratio were 0.31% δk and 1.9%, respectively. The maximum error of reaction rate ratio was 8% for 238 U-to- 235 U fission of ZEBRA lattice against the reference calculation done by MCNP5. (authors)

  1. Assessment of nuclear data needs for broad-group SCALE library related to WWER spent fuel applications

    International Nuclear Information System (INIS)

    Zalesky, K.; Markova, L.

    1999-12-01

    A preliminary study aimed at the issue of feasibility to generate a broad-group SCALE library related to WWER spent fuel applications was made. The SCALE code system has been installed and is being used in many countries operating WWER-type reactors for criticality and shielding analyses as well as spent fuel isotopic inventory calculations but still without an extensive validation and verification for the WWER environment. This study should be a contribution to QA connected with the SCALE code system application for the WWER calculations as a basis on which the generation of the specific WWER SCALE library can be prepared. Possible ways of the broad-group library development are described. (author)

  2. New WIMS library generation from ENDF/B6 and effect of resonance group structure on cell parameters

    International Nuclear Information System (INIS)

    Pazirandeh, Ali; Tabesh, Alireza

    2002-01-01

    Due to inaccessibility to NJOY, steps were taken to create WIMS library, which can be extracted from ENDF/B6 without using NJOY. In addition to using preprocessing codes few programs were written to calculate integral resonance, slowing down power per unit lethargy, potential scattering, and differential scattering cross section, scattering matrices. For neutrons with energy above 4 eV, isotropic elastic scattering was assumed. For neutrons below 4 eV the free gas model was used, except for light elements, which tabulated values of S(α,β) in ENDF/B6 used. The Goldstein-Cohen factors are taken from WIMKAL88.Lib. The integral resonance with self absorption per unit lethargy was obtained from GROUPIE output. The P 1 scattering matrices are calculated only for four elements, namely H, D, C and O at 300 K. In order to examine the created libraries, k eff , δ 28 , ρ 28 , ρ 25 and CR are calculated using new WIMS library, WIMKAL88.Lib and NEA329.Lib. The results showed general agreement. The controversial issue of WIMS library group structure, particularly in resonance region has raised the question of whether the number of resonance group i.e., 13 is optimized. We generated different WIMS libraries consisting of 5, 8, 13, 18 and 23 resonance groups. The main aim was to examine the effect to resonance group structure on calculated core parameters, mainly, k eff , δ 28 , ρ 28 , ρ 25 and CR. These parameters are also calculated and compared with those obtained using WIMKAL88, and NEA329 libraries. (author)

  3. Production of neutronic discrete equations for a cylindrical geometry in one group energy and benchmark the results with MCNP-4B code with one group energy library

    International Nuclear Information System (INIS)

    Salehi, A. A.; Vosoughi, N.; Shahriari, M.

    2002-01-01

    In reactor core neutronic calculations, we usually choose a control volume and investigate about the input, output, production and absorption inside it. Finally, we derive neutron transport equation. This equation is not easy to solve for simple and symmetrical geometry. The objective of this paper is to introduce a new direct method for neutronic calculations. This method is based on physics of problem and with meshing of the desired geometry, writing the balance equation for each mesh intervals and with notice to the conjunction between these mesh intervals, produce the final discrete equation series without production of neutron transport differential equation and mandatory passing form differential equation bridge. This method, which is named Direct Discrete Method, was applied in static state, for a cylindrical geometry in one group energy. The validity of the results from this new method are tested with MCNP-4B code with a one group energy library. One energy group direct discrete equation produces excellent results, which can be compared with the results of MCNP-4B

  4. ENEA-Bologna production and testing of JEF-2.2 multi-group cross section libraries for nuclear fission applications

    International Nuclear Information System (INIS)

    Pescarini, M.; Orsi, R.; Martinelli, T.; Sinitsa, V.; Blokhin, A.I.

    2005-01-01

    The ENEA-Bologna Nuclear Data Group produced the VITJEF22.BOLIB (NEA-1699/01 ZZ VITJEF22.BOLIB) and MATJEF22.BOLIB (NEA-1740/01 ZZ MATJEF22.BOLIB) fine-group coupled neutron and photon (199 n + 42 γ) cross section libraries for nuclear fission applications, respectively in AMPX and MATXS format and based on the JEF-2.2 European nuclear data file. Both the libraries were produced from the same set of cross section files in GENDF format, generated with the NJOY-94.66 nuclear data processing system. The present libraries can be considered as European counterparts of the VITAMIN-B6 (DLC-0184 ZZ VITAMIN-B6) American library in AMPX format, based on the ENDF/B-VI Release 3 American nuclear data file. In fact they have the same general features and the same neutron and photon energy group structures as VITAMIN-B6. In particular, all these libraries are pseudo-problem-independent and based on the Bondarenko (f-factor) method for the treatment of neutron resonance self-shielding and temperature effects. Each ENEA-Bologna library contains a set of 133 nuclide cross section files processed at 4 temperatures (300 K, 600 K, 1000 K and 2100 K) and obtained for the most part with 6 to 8 values of the background cross section σ 0 . Thermal scattering cross sections were processed at all the temperatures available in the JEF-2.2 thermal scattering law data file for 5 additional bound nuclides: H-1 in light water, H-1 in polyethylene, H-2 in heavy water, C in graphite and Be in beryllium metal. Collapsed working libraries of self-shielded cross sections in the formats used by the deterministic transport codes of the DANTSYS and DOORS systems can be generated from VITJEF22.BOLIB and MATJEF22.BOLIB through, respectively, further problem-dependent data processing with the AMPX or SCAMPI nuclear data processing systems and with the TRANSX code. (authors)

  5. KAFAX-F22 : development and benchmark of multi-group library for fast reactor using JEF-2.2. Neutron 80 group and Photon 24 group

    International Nuclear Information System (INIS)

    Kim, Jung Do; Gil, Choong Sup.

    1997-03-01

    The KAFAX-F22 was developed from JEF-2.2, which is a MATXS format, multigroup library of fast reactor. The KAFAX-F22 has 80 and 24 energy group structures for neutron and photon, respectively. It includes 89 nuclide data processed by NJOY94.38. The TRANSX/TWODANT system was used for benchmark calculations of fast reactor and one- and two-dimensional calculations of ONEDANT and TWODANT were carried out with 80 group, P 3 S 16 and with 25 group, P 3 S 8 , respectively. The average values of multiplication factors are 0.99652 for MOX cores, 1.00538 for uranium cores and 1.00032 for total cores. Various central reaction rate ratios also give good agreements with the experimental values considering experimental uncertainties except for VERA-11A, VERA-1B, ZPR-6-7 and ZPR-6-6A cores of which experimental values seem to involve some problems. (author). 13 refs., 18 tabs., 2 figs

  6. ZZ ORIGEN2.2-UPJ, A complete package of ORIGEN2 libraries based on JENDL-3.2 and JENDL-3.3

    International Nuclear Information System (INIS)

    Ishikawa, Makoto; Kataoka, Masaharu; Ohkawachi, Yasushi; Ohki, Shigeo; JIN, Tomoyuki; Katakura, Jun-ich; Suyama, Kenya; Yanagisawa, Hiroshi; Matsumoto, Hideki; ONOUE, Akira; Sasahara, Akihiro

    2006-01-01

    1 - Description: ORLIBJ32 is a package of the libraries for ORIGEN2 code based on JENDL-3.2(NEA-1642). The one grouped cross section data for PWR and BWR were compiled using the burnup calculation results by SWAT code. The FBR libraries were compiled by the analysis system used at JNC for FBR core calculation. The fission yield and decay constants data were also updated using the second version of the JNDC FP library. In ORLIBJ32, not only one-grouped cross section data but also variable actinide cross section data are prepared, using a code written in FORTRAN77. The routines should be linked to the Original ORIGEN2.1 program. The LWR Libraries are prepared based on the current PWR fuel assembly specification, and the FBR libraries are based on the request by the Japanese FBR researchers. Before compiling the libraries, the specification of fuel assembly was completely reviewed and evaluated by the members of Working Group in the Japanese Nuclear Data Committee, 'working group on the evaluation of the amount of isotope generation'. ORLIBJ33 is a new libraries based on JENDL-3.3 following the release of JENDL-3.3. The parameters used to prepare the library are the same as those of ORLIBJ32. The Original version or ORLIBJ33 is coupled with ORIGEN2.1. But after the release of ORIGEN2.2 from ORNL as CCC-0371 through RSICC, several requests for a combination with ORLIBJ33 and ORIGEN2.2 were received. During the development of ORLIBJ33, released as NEA-1642, authors found a problem in the library maker for FBR libraries, and consequently it was revised and tested in JNC-Oarai. This package 'ORIGEN2.2-UPJ' contains: - updated source code of ORIGEN2.2 of CCC-0371 to use ORLIBJ32 and ORLIBJ33, - all Original libraries in CCC-0371, - ORLIBJ32 in NEA-164/03 (but libraries for FBR are revised), - and ORLIBJ33. In this package, decay data based on the second version of the JNDC FP library and, photon and decay data libraries based on JENDL-3.3 are also included. NLB and NLIB

  7. No Natives Here: A Focus Group Study of Student Perceptions of Web 2.0 and the Academic Library

    Science.gov (United States)

    Burhanna, Kenneth J.; Seeholzer, Jamie

    2009-01-01

    This study explores Web 2.0 technologies in an academic library through focus groups with undergraduates at Kent State University. Results reveal that students, despite being heavy users, are less sophisticated and expressive in their use of Web 2.0 than presumed. Students set clear boundaries between educational and social spaces on the Web, and…

  8. The Public's Attitude Toward Public Library Services in Essex County, New Jersey; A Research Study Conducted for the Essex County Library Directors Group Public Relations Committee.

    Science.gov (United States)

    Market Dynamics, Inc., Princeton, NJ.

    In order to structure an effective campaign aimed at increasing the usage of the public libraries in Essex County, New Jersey, this research project was undertaken to determine the consumer attitudes toward various aspects of public library services. These aspects include: extent of public library usage; awareness of library services offered,…

  9. A Polymerase Chain Reaction-Based Method for Isolating Clones from a Complimentary DNA Library in Sheep

    Science.gov (United States)

    Friis, Thor Einar; Stephenson, Sally; Xiao, Yin; Whitehead, Jon

    2014-01-01

    The sheep (Ovis aries) is favored by many musculoskeletal tissue engineering groups as a large animal model because of its docile temperament and ease of husbandry. The size and weight of sheep are comparable to humans, which allows for the use of implants and fixation devices used in human clinical practice. The construction of a complimentary DNA (cDNA) library can capture the expression of genes in both a tissue- and time-specific manner. cDNA libraries have been a consistent source of gene discovery ever since the technology became commonplace more than three decades ago. Here, we describe the construction of a cDNA library using cells derived from sheep bones based on the pBluescript cDNA kit. Thirty clones were picked at random and sequenced. This led to the identification of a novel gene, C12orf29, which our initial experiments indicate is involved in skeletal biology. We also describe a polymerase chain reaction-based cDNA clone isolation method that allows the isolation of genes of interest from a cDNA library pool. The techniques outlined here can be applied in-house by smaller tissue engineering groups to generate tools for biomolecular research for large preclinical animal studies and highlights the power of standard cDNA library protocols to uncover novel genes. PMID:24447069

  10. A problem-based learning curriculum in transition: the emerging role of the library.

    OpenAIRE

    Eldredge, J D

    1993-01-01

    This case study describes library education programs that serve the University of New Mexico School of Medicine, known for its innovative problem-based learning (PBL) curricular track. The paper outlines the specific library instruction techniques that are integrated into the curriculum. The adaptation of library instruction to a PBL mode of medical education, including the use of case studies, is discussed in detail. Also addressed are the planning processes for the new PBL curriculum schedu...

  11. BUGJEFF311.BOLIB (JEFF-3.1.1) and BUGENDF70.BOLIB (ENDF/B-VII.0) - Generation Methodology and Preliminary Testing of two ENEA-Bologna Group Cross Section Libraries for LWR Shielding and Pressure Vessel Dosimetry

    Science.gov (United States)

    Pescarini, Massimo; Sinitsa, Valentin; Orsi, Roberto; Frisoni, Manuela

    2016-02-01

    Two broad-group coupled neutron/photon working cross section libraries in FIDO-ANISN format, dedicated to LWR shielding and pressure vessel dosimetry applications, were generated following the methodology recommended by the US ANSI/ANS-6.1.2-1999 (R2009) standard. These libraries, named BUGJEFF311.BOLIB and BUGENDF70.BOLIB, are respectively based on JEFF-3.1.1 and ENDF/B-VII.0 nuclear data and adopt the same broad-group energy structure (47 n + 20 γ) of the ORNL BUGLE-96 similar library. They were respectively obtained from the ENEA-Bologna VITJEFF311.BOLIB and VITENDF70.BOLIB libraries in AMPX format for nuclear fission applications through problem-dependent cross section collapsing with the ENEA-Bologna 2007 revision of the ORNL SCAMPI nuclear data processing system. Both previous libraries are based on the Bondarenko self-shielding factor method and have the same AMPX format and fine-group energy structure (199 n + 42 γ) as the ORNL VITAMIN-B6 similar library from which BUGLE-96 was obtained at ORNL. A synthesis of a preliminary validation of the cited BUGLE-type libraries, performed through 3D fixed source transport calculations with the ORNL TORT-3.2 SN code, is included. The calculations were dedicated to the PCA-Replica 12/13 and VENUS-3 engineering neutron shielding benchmark experiments, specifically conceived to test the accuracy of nuclear data and transport codes in LWR shielding and radiation damage analyses.

  12. Generation of a library of two-group diffusion parameters for SPPS-1,6 by HELIOS

    International Nuclear Information System (INIS)

    Petkov, P.T.; Haralampieva, C.V.; Simeonov, T.; Stojanova, I.; Kamenov, K.

    2000-01-01

    The two-group three-dimensional nodal diffusion code SPPS-1.6 has been used for many years for steady-state neutronics calculations of the WWER-440 reactors at Kozloduy NPP. The old library of two-group diffusion parameters for SPPS-1.6 has been generated by WIMSD4 with a nuclear data library compiled from three different libraries. The current paper presents our experience in generating a new library for SPPS-1.6 by the HELIOS lattice code. The accuracy of the current-coupling collision probability (CCCP) method in calculating a single WWER-440 assembly has been studied first. Among all possible angular discretization of the interface partial currents, called coupling orders, only coupling order 3 is suitable for hexagonal cells. Dividing each cell side into 3 segments an accuracy of 100 pcm has been achieved. The accuracy in calculating the absorber problem was estimated at 1%, which means about 10% error in the control assemblies efficiency. The accuracy for small core-reflector problems is 1% as well. The general conclusion is that HELIOS is accurate enough for assembly calculations, but inadequate for absorber and core-reflector problems. (Authors)

  13. Curriculum-based library instruction from cultivating faculty relationships to assessment

    CERN Document Server

    Blevins, Amy

    2014-01-01

    Curriculum-Based Library Instruction: From Cultivating Faculty Relationships to Assessment highlights the movement beyond one-shot instruction sessions, specifically focusing on situations where academic librarians have developed curriculum based sessions and/or become involved in curriculum committees.

  14. Collection evaluation in University libraries (II. Methods based on collection use

    Directory of Open Access Journals (Sweden)

    Àngels Massísimo i Sánchez de Boado

    2004-01-01

    Full Text Available This is our second paper devoted to the collection evaluation in the university libraries. Seven methods are described, based on collection use. Their advantages and disadvantages are discussed, as well as their usefulness for a range of library types

  15. Evidence-Based Practice and School Libraries: Interconnections of Evidence, Advocacy, and Actions

    Science.gov (United States)

    Todd, Ross J.

    2015-01-01

    This author states that a professional focus on evidence based practice (EBP) for school libraries emerged from the International Association of School Librarianship conference when he presented the concept. He challenged the school library profession to actively engage in professional and reflective practices that chart, measure, document, and…

  16. The Experience of Evidence-Based Practice in an Australian Public Library: An Ethnography

    Science.gov (United States)

    Gillespie, Ann; Partridge, Helen; Bruce, Christine; Howlett, Alisa

    2016-01-01

    Introduction: This paper presents the findings from a project that investigated the lived experiences of library and information professionals in relation to evidence-based practice within an Australian public library. Method: The project employed ethnography, which allows holistic description of people's experiences within a particular community…

  17. Analysis of Environmental Friendly Library Based on the Satisfaction and Service Quality: study at Library “X”

    Science.gov (United States)

    Herdiansyah, Herdis; Satriya Utama, Andre; Safruddin; Hidayat, Heri; Gema Zuliana Irawan, Angga; Immanuel Tjandra Muliawan, R.; Mutia Pratiwi, Diana

    2017-10-01

    One of the factor that influenced the development of science is the existence of the library, which in this case is the college libraries. Library, which is located in the college environment, aims to supply collections of literatures to support research activities as well as educational for students of the college. Conceptually, every library now starts to practice environmental principles. For example, “X” library as a central library claims to be an environmental friendly library for practicing environmental friendly management, but the X library has not inserted the satisfaction and service aspect to the users, including whether it is true that environmental friendly process is perceived by library users. Satisfaction can be seen from the comparison between expectations and reality of library users. This paper analyzes the level of library user satisfaction with library services in the campus area and the gap between expectations and reality felt by the library users. The result of the research shows that there is a disparity between the hope of library management, which is sustainable and environmentally friendly with the reality in the management of the library, so that it has not given satisfaction to the users yet. The gap value of satisfaction that has the biggest difference is in the library collection with the value of 1.57; while for the smallest gap value is in the same service to all students with a value of 0.67.

  18. Up, up, and Away: How a Group of Researchers Is Reinventing School Libraries

    Science.gov (United States)

    Whelan, Debra Lau

    2010-01-01

    These days it seems like school librarians are under attack, if not already an endangered species. After eight years of the No Child Left Behind Act--which, paradoxically, chipped away at many library positions--recent state and local budget shortfalls have led to rounds and rounds of layoffs for school librarians. While things are tough in the…

  19. MT71x: Multi-Temperature Library Based on ENDF/B-VII.1

    Energy Technology Data Exchange (ETDEWEB)

    Conlin, Jeremy Lloyd [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Parsons, Donald Kent [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Gray, Mark Girard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lee, Mary Beth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); White, Morgan Curtis [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-16

    The Nuclear Data Team has released a multitemperature transport library, MT71x, based upon ENDF/B-VII.1 with a few modifications as well as additional evaluations for a total of 427 isotope tables. The library was processed using NJOY2012.39 into 23 temperatures. MT71x consists of two sub-libraries; MT71xMG for multigroup energy representation data and MT71xCE for continuous energy representation data. These sub-libraries are suitable for deterministic transport and Monte Carlo transport applications, respectively. The SZAs used are the same for the two sub-libraries; that is, the same SZA can be used for both libraries. This makes comparisons between the two libraries and between deterministic and Monte Carlo codes straightforward. Both the multigroup energy and continuous energy libraries were verified and validated with our checking codes checkmg and checkace (multigroup and continuous energy, respectively) Then an expanded suite of tests was used for additional verification and, finally, verified using an extensive suite of critical benchmark models. We feel that this library is suitable for all calculations and is particularly useful for calculations sensitive to temperature effects.

  20. Generation, Testing, and Validation of a WIMS-D/4 Multigroup Cross-Section Library Based on the JENDL-3.2 Nuclear Data

    International Nuclear Information System (INIS)

    Rahman, Mafizur; Takano, Hideki

    2001-01-01

    A new 69-group library of multigroup constants for the lattice code WIMS-D/4 has been generated with an improved resonance treatment, processing nuclear data from JENDL-3.2 by NJOY91.108. A parallel ENDF/B-VI based library has also been constructed for intercomparison of results. Benchmark calculations for a number of thermal reactor critical assemblies of both uranium and plutonium fuels have been performed with the code WIMS-D/4.1 with its three different libraries: the original WIMS library (NEA-0329/10) and the new ENDF/B-VI and JENDL-3.2 based libraries. The results calculated with both ENDF and JENDL based libraries show a similar tendency and are found in better agreement with the experimental values. Benchmark parameters are further calculated with the comprehensive lattice code SRAC95. The results from SRAC95 and WIMS-D/4.1 (both using JENDL-3.2 based libraries) agree well with each other. The new library is also verified for its applicability to mixed-oxide cores of varying plutonium contents

  1. ZZ DECNET-GENDF, Fusion Damage Library of 175 Neutron and 42 Photon VITAMIN-J Groups

    International Nuclear Information System (INIS)

    1997-01-01

    1 - Description of program or function: DECNET is a library for fusion damage computations of 175 neutron + 42 photon VITAMIN-J energy group with the standard weighting function: Maxwellian (at the temperature to which the material is referenced) + 1/E + Fission Spectrum + 1/E + Fusion Peak + 1/E; it includes neutron kerma and gamma-ray production data from radioactive nuclei at 3 temperatures with the same materials of ZZ-GEFF-2-GENDF (see below) from 1-H-1 to Bi-209, mostly taken from EFF-2 with some nuclides from JEF-2.2 - Ag-107, Ag-109, Cd, the 6 Hf isotopes and the 4 W isotopes; however the list of the materials disagrees with that of GEFF-2 in that all elemental nuclides have been split into the components isotopes to follow the respective decay chain and not all materials of GEFF-2 produces nuclei which disintegrate. The library has been produced by the DECKER code which has been developed for this purpose. The format of the library is GENDF. 2 - Method of solution: The library has been produced by the DECKER code developed at ENEA Bologna for this purpose. The code reads the nuclide(s) for which decay kerma and photon production are requested and looks for the necessary data on the RDD (Radioactive Decay Data) file from JEF-2.2

  2. Dynamic combinatorial libraries based on hydrogen-bonde molecular boxes

    NARCIS (Netherlands)

    Kerckhoffs, J.M.C.A.; Mateos timoneda, Miguel; Reinhoudt, David; Crego Calama, Mercedes

    2007-01-01

    This article describes two different types of dynamic combinatorial libraries of host and guest molecules. The first part of this article describes the encapsulation of alizarin trimer 2 a3 by dynamic mixtures of up to twenty different self-assembled molecular receptors together with the

  3. Analyses of criticality and reactivity for TRACY experiments based on JENDL-3.3 data library

    International Nuclear Information System (INIS)

    Sono, Hiroki; Miyoshi, Yoshinori; Nakajima, Ken

    2003-01-01

    The parameters on criticality and reactivity employed for computational simulations of the TRACY supercritical experiments were analyzed using a recently revised nuclear data library, JENDL-3.3. The parameters based on the JENDL-3.3 library were compared to those based on two former-used libraries, JENDL-3.2 and ENDF/B-VI. In the analyses computational codes, MVP, MCNP version 4C and TWOTRAN, were used. The following conclusions were obtained from the analyses: (1) The computational biases of the effective neutron multiplication factor attributable to the nuclear data libraries and to the computational codes do not depend the TRACY experimental conditions such as fuel conditions. (2) The fractional discrepancies in the kinetic parameters and coefficients of reactivity are within ∼5% between the three libraries. By comparison between calculations and measurements of the parameters, the JENDL-3.3 library is expected to give closer values to the measurements than the JENDL-3.2 and ENDF/B-VI libraries. (3) While the reactivity worth of transient rods expressed in the $ unit shows ∼5% discrepancy between the three libraries according to their respective β eff values, there is little discrepancy in that expressed in the Δk/k unit. (author)

  4. ZZ WIMS-D/4LIB, 61, 64, 69, 76 and 79 energy groups WIMS-D/4 libraries

    International Nuclear Information System (INIS)

    2002-01-01

    1 - Description: Format: WIMS; Number of groups: 61,64,69,76,79 energy groups; Nuclides: The following nuclides are included: H 1 , H 1 (in H 2 O), H 1 (in ZrH), H 2 , H 2 (in D 2 O), He 3 , He 4 , Li 6 , Li 7 , Be 9 , B 1 0, B 1 1, C, C (in graphite), N 14 , 0 16 , F, Na, Al, Si, P 31 , S 32 , K, Ti, V, Cr, Mn 55 , Fe, Co 59 , Ni, Cu, Cu 63 , Zr, Nb 93 , Mo, Mo 92 , Mo 94 , Mo 95 , Mo 96 , Mo 97 , Mo 98 , Mo 99 , Mo 100 , Ag 107 , Ag 109 , Cd, In 113 , In 115 , Sn, Gd, Dy 164 , Er 166 , Er 167 , Lu 176 , Hf, Hf 174 , Hf 176 , Hf 177 , Hf 178 , Hf 179 , Hf 180 , Ta 181 , Au 197 , Pb. The following fission products are included: Kr 83 , Mo 95 , Tc 99 , Ru 101 , Ru 103 , Rh 103 , Rh 105 , Pd 105 , Pd 108 , Ag 109 , Cd 113 , In 115 , I 127 , I 135 , Xe 131 , Xe 135 , Cs 133 , Cs 134 , Cs 135 , Nd 143 , Nd 145 , Pm 147 , Pm 148g , Pm 148m , Pm 149 , Sm 147 , Sm 148 , Sm 149 , Sm 150 , Sm 151 , Sm 152 , Eu 153 , Eu 154 , Eu 155 , Gd 157 , Pseudo F.P., Dummy ID = 237 Abs. XS = 1.0 E-5 B The following actinides are included: Th 232 , Pa 233 , U 233 , U 234 , U 235 , U 236 , U 237 , U 238 , Np 237 , Np 238 , Np 239 , Pu 238 , Pu 239 , Pu 240 , Pu 241 , Pu 242 , Am 241 , Am 242g , Am 242m , Am 243 , Cm 242 , Cm 243 , Cm 244 ; absorber ID = 1000. Origin: ENDF/B-V or IV and JENDL-2(Rev.1); and from ENDL-84, where data was not available in ENDF/B. Neutron cross section library for thermal reactor design analysis with 61, 64, 69, 76, and 79 energy WIMS groups structure. Weighting Spectrum: Within-group weighting fluxes were computed. The weighting spectrum is: 4KT>E>0eV (S(E)=E.Exp(-E/(KT))/KT Maxwellian; 670 KeV>E≥4KT (S(E)=C1/E 1/E; 10 MeV≥E≥670 KeV (S(E)=C2.Exp(-E/Wa).Sinh(E.Wb) 1/2 Fission; KT 0.025 eV; Wa = 9.65 E+05; Wb = 2.29 E-06 The constants C1 and C2 are defined for continuity of the spectrum function. 2 - Methods: The library was produced using preprocessing codes to extract data from ENDF/B-VI or and JENDL-2 (Rev.1); and from where data was not available in

  5. Evidence-based medicine and the development of medical libraries in China.

    Science.gov (United States)

    Huang, Michael Bailou; Cheng, Aijun; Ma, Lu

    2009-07-01

    This article elaborates on the opportunities and challenges that evidence-based medicine (EBM) has posed to the development of medical libraries and summarizes the research in the field of evidence-based medicine and achievements of EBM practice in Chinese medical libraries. Issues such as building collections of information resources, transformation of information services models, human resources management, and training of medical librarians, clinicians, and EBM users are addressed. In view of problems encountered in EBM research and practice, several suggestions are made about important roles medical libraries can play in the future development of EBM in China.

  6. PCR-based cDNA library construction: general cDNA libraries at the level of a few cells.

    OpenAIRE

    Belyavsky, A; Vinogradova, T; Rajewsky, K

    1989-01-01

    A procedure for the construction of general cDNA libraries is described which is based on the amplification of total cDNA in vitro. The first cDNA strand is synthesized from total RNA using an oligo(dT)-containing primer. After oligo(dG) tailing the total cDNA is amplified by PCR using two primers complementary to oligo(dA) and oligo(dG) ends of the cDNA. For insertion of the cDNA into a vector a controlled trimming of the 3' ends of the cDNA by Klenow enzyme was used. Starting from 10 J558L ...

  7. Agricultural Library Information Retrieval Based on Improved Semantic Algorithm

    OpenAIRE

    Meiling , Xie

    2014-01-01

    International audience; To support users to quickly access information they need from the agricultural library’s vast information and to improve the low intelligence query service, a model for intelligent library information retrieval was constructed. The semantic web mode was introduced and the information retrieval framework was designed. The model structure consisted of three parts: Information data integration, user interface and information retrieval match. The key method supporting retr...

  8. Using focus groups to investigate service quality determinants for customer satisfaction in selected university libraries in Sri Lanka

    Directory of Open Access Journals (Sweden)

    Chaminda Jayasundara

    2010-01-01

    Full Text Available This study aimed at establishing service quality determinants which may affect customer satisfaction in university libraries in Sri Lanka. Using the literature, 113 service quality determinants were identified. These were then reviewed by eight focus groups in four different universities. Forty of the determinants were perceived to be applicable to their context. The participants also added 14 quality requirements which they thought were not provided for in the list. Finally, the content and face validity of the 54 determinants were evaluated by a panel of experts who ultimately reduced them to 50. This study recommends the use of the identified quality determinants by library administrators and policymakers in the higher education sector in Sri Lanka to gauge the levels of customer satisfaction and assure quality of service.

  9. Optimal protein library design using recombination or point mutations based on sequence-based scoring functions.

    Science.gov (United States)

    Pantazes, Robert J; Saraf, Manish C; Maranas, Costas D

    2007-08-01

    In this paper, we introduce and test two new sequence-based protein scoring systems (i.e. S1, S2) for assessing the likelihood that a given protein hybrid will be functional. By binning together amino acids with similar properties (i.e. volume, hydrophobicity and charge) the scoring systems S1 and S2 allow for the quantification of the severity of mismatched interactions in the hybrids. The S2 scoring system is found to be able to significantly functionally enrich a cytochrome P450 library over other scoring methods. Given this scoring base, we subsequently constructed two separate optimization formulations (i.e. OPTCOMB and OPTOLIGO) for optimally designing protein combinatorial libraries involving recombination or mutations, respectively. Notably, two separate versions of OPTCOMB are generated (i.e. model M1, M2) with the latter allowing for position-dependent parental fragment skipping. Computational benchmarking results demonstrate the efficacy of models OPTCOMB and OPTOLIGO to generate high scoring libraries of a prespecified size.

  10. Translational Researchers' Perceptions of Data Management Practices and Data Curation Needs: Findings from a Focus Group in an Academic Health Sciences Library

    Science.gov (United States)

    Bardyn, Tania P.; Resnick, Taryn; Camina, Susan K.

    2012-01-01

    How translational researchers use data is becoming an important support function for libraries to understand. Libraries' roles in this increasingly complex area of Web librarianship are often unclearly defined. The authors conducted two focus groups with physicians and researchers at an academic medical center, the UCLA David Geffen School of…

  11. Collection-based analysis of selected medical libraries in the Philippines using Doody's Core Titles.

    Science.gov (United States)

    Torres, Efren

    2017-01-01

    This study assessed the book collection of five selected medical libraries in the Philippines, based on Doodys' Essential Purchase List for basic sciences and clinical medicine, to compare the match and non-match titles among libraries, to determine the strong and weak disciplines of each library, and to explore the factors that contributed to the percentage of match and non-match titles. List checking was employed as the method of research. Among the medical libraries, De La Salle Health Sciences Institute and University of Santo Tomas had the highest percentage of match titles, whereas Ateneo School of Medicine and Public Health had the lowest percentage of match titles. University of the Philippines Manila had the highest percentage of near-match titles. De La Salle Health Sciences Institute and University of Santo Tomas had sound medical collections based on Doody's Core Titles. Collectively, the medical libraries shared common collection development priorities, as evidenced by similarities in strong areas. Library budget and the role of the library director in book selection were among the factors that could contribute to a high percentage of match titles.

  12. Investigating User Interfaces of Non-Iranian Digital Libraries based on Social Bookmarking Capabilities and Characteristics to Use by Iranian Digital Libraries

    Directory of Open Access Journals (Sweden)

    Zahra Naseri

    2016-08-01

    Full Text Available Current study aims to investigate the status of user interfaces of non-Iranian digital libraries’ based on social bookmarking capabilities and characteristics to use by Iranian digital libraries. This research studies the characteristics and capabilities of top digital libraries’ user interfaces in the world based on social bookmarking used by library users. This capability facilitates producing, identifying, organizing, and sharing contents using tags. Survey method was used with descriptive-analytical approach in this study. Populations include non-Iranian digital libraries interfaces. Top ten digital libraries’ interfaces were selected as the sample. A researcher-made checklist prepared based on literature review and investigating four distinguished websites (Library Thing, Delicious, Amazon, and Google Book. Faced validity evaluated by 10 experts’ viewpoints, then reliability calculated 0.87.Findings of this study are important because of two reasons: first, it provides a comprehensive and an unambiguous vision for recognizing user interfaces’ basic capabilities and characteristics based on social bookmarking. Second, it can provide a base for designing digital libraries in Iran. The results showed that the majority of digital libraries around the world had not used web 2.0 characteristics such as producing, identifying, organizing, and sharing contents except two digital libraries (Google Books, and Ibiblio.

  13. The LAW library

    International Nuclear Information System (INIS)

    Green, N.M.; Parks, C.V.; Arwood, J.W.

    1989-01-01

    The 238 group LAW library is a new multigroup library based on ENDF/B-V data. It contains data for 302 materials and will be distributed by the Radiation Shielding Information Center, located at Oak Ridge National Laboratory. It was generated for use in neutronics calculations required in radioactive waste analyses, though it has equal utility in any study requiring multigroup neutron cross sections

  14. Incorporating Library School Interns on Academic Library Subject Teams

    Science.gov (United States)

    Sargent, Aloha R.; Becker, Bernd W.; Klingberg, Susan

    2011-01-01

    This case study analyzes the use of library school interns on subject-based teams for the social sciences, humanities, and sciences in the San Jose State University Library. Interns worked closely with team librarians on reference, collection development/management, and instruction activities. In a structured focus group, interns reported that the…

  15. Generation and validation of the WIMS-D5 library based on JENDL-3.2

    International Nuclear Information System (INIS)

    Gil, Choong-Sup; Kim, Jung-Do

    2002-01-01

    A WIMS-D5 library based on JENDL-3.2 has been prepared and is being tested against benchmark problems. Several sensitivity calculations for stability confirmation of the library were carried out, such as fission spectrum dependency and the self-shielding effects of the elastic scattering cross sections and the self-shielding effects 240 Pu and 242 Pu capture cross sections below 4.0 eV. The results of benchmark calculations with the libraries based on JENDL-3.2, ENDF/B-VI.5, JEF-2.2, and the 1986 WIMS-D library were intercompared. The multiplication factors for the thermal lattices are slightly underpredicted by all libraries (up to 1% with ENDF/B-VI.5). The k eff values with the library based on JENDL-3.2 are slightly higher than those of ENDF/B-VI.5 and JEF-2.2. The spectral indices for the lattices with JENDL-3.2 agree with the measured quantities within the uncertainties of the experiments. The calculated amounts of some isotopes such as 149 Sm, 237 Np, 238 Pu, 242 Cm and 243 Cm show large differences from the measured or reference values. (author)

  16. Douglass Rationalization: An Evaluation of a Team Environment and a Computer-Based Task in Academic Libraries

    Science.gov (United States)

    Denda, Kayo; Smulewitz, Gracemary

    2004-01-01

    In the contemporary library environment, the presence of the Internet and the infrastructure of the integrated library system suggest an integrated internal organization. The article describes the example of Douglass Rationalization, a team-based collaborative project to refocus the collection of Rutgers' Douglass Library, taking advantage of the…

  17. Compilation of MCNP data library based on JENDL-3T and test through analysis of benchmark experiment

    International Nuclear Information System (INIS)

    Sakurai, K.; Sasamoto, N.; Kosako, K.; Ishikawa, T.; Sato, O.; Oyama, Y.; Narita, H.; Maekawa, H.; Ueki, K.

    1989-01-01

    Based on an evaluated nuclear data library JENDL-3T, a temporary version of JENDL-3, a pointwise neutron cross section library for MCNP code is compiled which involves 39 nuclides from H-1 to Am-241 which are important for shielding calculations. Compilation is performed with the code system which consists of the nuclear data processing code NJOY-83 and library compilation code MACROS. Validity of the code system and reliability of the library are certified by analysing benchmark experiments. (author)

  18. Production and testing of the ENEA-Bologna VITJEFF32.BOLIB (JEFF-3.2) multi-group (199 n + 42 γ) cross section library in AMPX format for nuclear fission applications

    Science.gov (United States)

    Pescarini, Massimo; Orsi, Roberto; Frisoni, Manuela

    2017-09-01

    The ENEA-Bologna Nuclear Data Group produced the VITJEFF32.BOLIB multi-group coupled neutron/photon (199 n + 42 γ) cross section library in AMPX format, based on the OECD-NEA Data Bank JEFF-3.2 evaluated nuclear data library. VITJEFF32.BOLIB was conceived for nuclear fission applications as European counterpart of the ORNL VITAMIN-B7 similar library (ENDF/B-VII.0 data). VITJEFF32.BOLIB has the same neutron and photon energy group structure as the former ORNL VITAMIN-B6 reference library (ENDF/B-VI.3 data) and was produced using similar data processing methodologies, based on the LANL NJOY-2012.53 nuclear data processing system for the generation of the nuclide cross section data files in GENDF format. Then the ENEA-Bologna 2007 Revision of the ORNL SCAMPI nuclear data processing system was used for the conversion into the AMPX format. VITJEFF32.BOLIB contains processed cross section data files for 190 nuclides, obtained through the Bondarenko (f-factor) method for the treatment of neutron resonance self-shielding and temperature effects. Collapsed working libraries of self-shielded cross sections in FIDO-ANISN format, used by the deterministic transport codes of the ORNL DOORS system, can be generated from VITJEFF32.BOLIB through the cited SCAMPI version. This paper describes the methodology and specifications of the data processing performed and presents some results of the VITJEFF32.BOLIB validation.

  19. Production and testing of the ENEA-Bologna VITJEFF32.BOLIB (JEFF-3.2 multi-group (199 n + 42 γ cross section library in AMPX format for nuclear fission applications

    Directory of Open Access Journals (Sweden)

    Pescarini Massimo

    2017-01-01

    Full Text Available The ENEA-Bologna Nuclear Data Group produced the VITJEFF32.BOLIB multi-group coupled neutron/photon (199 n + 42 γ cross section library in AMPX format, based on the OECD-NEA Data Bank JEFF-3.2 evaluated nuclear data library. VITJEFF32.BOLIB was conceived for nuclear fission applications as European counterpart of the ORNL VITAMIN-B7 similar library (ENDF/B-VII.0 data. VITJEFF32.BOLIB has the same neutron and photon energy group structure as the former ORNL VITAMIN-B6 reference library (ENDF/B-VI.3 data and was produced using similar data processing methodologies, based on the LANL NJOY-2012.53 nuclear data processing system for the generation of the nuclide cross section data files in GENDF format. Then the ENEA-Bologna 2007 Revision of the ORNL SCAMPI nuclear data processing system was used for the conversion into the AMPX format. VITJEFF32.BOLIB contains processed cross section data files for 190 nuclides, obtained through the Bondarenko (f-factor method for the treatment of neutron resonance self-shielding and temperature effects. Collapsed working libraries of self-shielded cross sections in FIDO-ANISN format, used by the deterministic transport codes of the ORNL DOORS system, can be generated from VITJEFF32.BOLIB through the cited SCAMPI version. This paper describes the methodology and specifications of the data processing performed and presents some results of the VITJEFF32.BOLIB validation.

  20. Balancing focused combinatorial libraries based on multiple GPCR ligands

    Science.gov (United States)

    Soltanshahi, Farhad; Mansley, Tamsin E.; Choi, Sun; Clark, Robert D.

    2006-08-01

    G-Protein coupled receptors (GPCRs) are important targets for drug discovery, and combinatorial chemistry is an important tool for pharmaceutical development. The absence of detailed structural information, however, limits the kinds of combinatorial design techniques that can be applied to GPCR targets. This is particularly problematic given the current emphasis on focused combinatorial libraries. By linking an incremental construction method (OptDesign) to the very fast shape-matching capability of ChemSpace, we have created an efficient method for designing targeted sublibraries that are topomerically similar to known actives. Multi-objective scoring allows consideration of multiple queries (actives) simultaneously. This can lead to a distribution of products skewed towards one particular query structure, however, particularly when the ligands of interest are quite dissimilar to one another. A novel pivoting technique is described which makes it possible to generate promising designs even under those circumstances. The approach is illustrated by application to some serotonergic agonists and chemokine antagonists.

  1. Exploring Peer-to-Peer Library Content and Engagement on a Student-Run Facebook Group

    Science.gov (United States)

    van Beynen, Kaya; Swenson, Camielle

    2016-01-01

    Student-run Facebook groups offer librarians a new means of interacting with students in their native digital domain. Facebook groups, a service launched in 2010 enables university students to create a virtual forum to discuss their concerns, issues, and promote events. While still a relatively new feature, these groups are increasingly being…

  2. Calculating the Fee-Based Services of Library Institutions: Theoretical Foundations and Practical Challenges

    Directory of Open Access Journals (Sweden)

    Sysіuk Svitlana V.

    2017-05-01

    Full Text Available The article is aimed at highlighting features of the provision of the fee-based services by library institutions, identifying problems related to the legal and regulatory framework for their calculation, and the methods to implement this. The objective of the study is to develop recommendations to improve the calculation of the fee-based library services. The theoretical foundations have been systematized, the need to develop a Provision for the procedure of the fee-based services by library institutions has been substantiated. Such a Provision would protect library institution from errors in fixing the fee for a paid service and would be an informational source of its explicability. The appropriateness of applying the market pricing law based on demand and supply has been substantiated. The development and improvement of accounting and calculation, taking into consideration both industry-specific and market-based conditions, would optimize the costs and revenues generated by the provision of the fee-based services. In addition, the complex combination of calculation leverages with development of the system of internal accounting together with use of its methodology – provides another equally efficient way of improving the efficiency of library institutions’ activity.

  3. Group representations, error bases and quantum codes

    Energy Technology Data Exchange (ETDEWEB)

    Knill, E

    1996-01-01

    This report continues the discussion of unitary error bases and quantum codes. Nice error bases are characterized in terms of the existence of certain characters in a group. A general construction for error bases which are non-abelian over the center is given. The method for obtaining codes due to Calderbank et al. is generalized and expressed purely in representation theoretic terms. The significance of the inertia subgroup both for constructing codes and obtaining the set of transversally implementable operations is demonstrated.

  4. When are emotions related to group-based appraisals? : A comparison between group-based emotions and general group emotions

    NARCIS (Netherlands)

    Kuppens, Toon; Yzerbyt, Vincent Y.

    2014-01-01

    In the literature on emotions in intergroup relations, it is not always clear how exactly emotions are group-related. Here, we distinguish between emotions that involve appraisals of immediate group concerns (i.e., group-based emotions) and emotions that do not. Recently, general group emotions,

  5. State Virtual Libraries

    Science.gov (United States)

    Pappas, Marjorie L.

    2003-01-01

    Virtual library? Electronic library? Digital library? Online information network? These all apply to the growing number of Web-based resource collections managed by consortiums of state library entities. Some, like "INFOhio" and "KYVL" ("Kentucky Virtual Library"), have been available for a few years, but others are just starting. Searching for…

  6. Availability and accessibility of evidence-based information resources provided by medical libraries in Australia.

    Science.gov (United States)

    Ritchie, A; Sowter, B

    2000-01-01

    This article reports on the results of an exploratory survey of the availability and accessibility of evidence-based information resources provided by medical libraries in Australia. Although barriers impede access to evidence-based information for hospital clinicians, the survey revealed that Medline and Cinahl are available in over 90% of facilities. In most cases they are widely accessible via internal networks and the Internet. The Cochrane Library is available in 69% of cases. The Internet is widely accessible and most libraries provide access to some full-text, electronic journals. Strategies for overcoming restrictions and integrating information resources with clinical workflow are being pursued. State, regional and national public and private consortia are developing agreements utilising on-line technology. These could produce cost savings and more equitable access to a greater range of evidence-based resources.

  7. Culture and group-based emotions? : Could group-based emotions be dialectical

    NARCIS (Netherlands)

    Lu, M.; Hamamura, T.; Doosje, B.; Suzuki, S.; Takemura, K.

    2016-01-01

    Group-based emotions are experienced when individuals are engaged in emotion-provoking events that implicate the in-group. This research examines the complexity of group-based emotions, specifically a concurrence of positive and negative emotions, focusing on the role of dialecticism, or a set of

  8. Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenomic library

    Directory of Open Access Journals (Sweden)

    Parachin Nádia

    2011-05-01

    Full Text Available Abstract Background Xylose isomerase (XI catalyses the isomerisation of xylose to xylulose in bacteria and some fungi. Currently, only a limited number of XI genes have been functionally expressed in Saccharomyces cerevisiae, the microorganism of choice for lignocellulosic ethanol production. The objective of the present study was to search for novel XI genes in the vastly diverse microbial habitat present in soil. As the exploitation of microbial diversity is impaired by the ability to cultivate soil microorganisms under standard laboratory conditions, a metagenomic approach, consisting of total DNA extraction from a given environment followed by cloning of DNA into suitable vectors, was undertaken. Results A soil metagenomic library was constructed and two screening methods based on protein sequence similarity and enzyme activity were investigated to isolate novel XI encoding genes. These two screening approaches identified the xym1 and xym2 genes, respectively. Sequence and phylogenetic analyses revealed that the genes shared 67% similarity and belonged to different bacterial groups. When xym1 and xym2 were overexpressed in a xylA-deficient Escherichia coli strain, similar growth rates to those in which the Piromyces XI gene was expressed were obtained. However, expression in S. cerevisiae resulted in only one-fourth the growth rate of that obtained for the strain expressing the Piromyces XI gene. Conclusions For the first time, the screening of a soil metagenomic library in E. coli resulted in the successful isolation of two active XIs. However, the discrepancy between XI enzyme performance in E. coli and S. cerevisiae suggests that future screening for XI activity from soil should be pursued directly using yeast as a host.

  9. Development of the tool for generating ORIGEN2 library based on JENDL-3.2 for FBR

    International Nuclear Information System (INIS)

    Ohkawachi, Yasushi; Fukushima, Manabu

    1999-05-01

    ORIGEN2 is one of the most widely-used burnup analysis code in the world. This code has one-grouped cross section libraries compiled for various types of reactors. However, these libraries have some problems. One is that these libraries were developed from old nuclear data libraries (ENDF/B-IV,V) and the other is that core and fuel designs from which these libraries are generated do not match the current analysis. In order to solve the problems, analysis tool is developed for generating ORIGEN2 library from JENDL-3.2 considering multi-energy neutron spectrum. And eight new libraries are prepared using this tool for analysis of sodium-cooled FBR. These new libraries are prepared for eight kinds of cores in total. Seven of them are made by changing core size (small core - large core), fuel type (oxide, nitride, metal) and Pu vector as a parameter. The eighth one is a Pu burner core. Burnup calculation using both new and original libraries, shows large difference in buildup or depletion numbers of nuclides among the libraries. It is estimated that the analysis result is greatly influenced by the neutron spectrum which is used in collapse of cross section. By using this tool or new libraries, it seems to improve evaluation accuracy of buildup or depletion numbers of nuclides in transmutation research on FBR fuel cycle. (author)

  10. Group recommendation strategies based on collaborative filtering

    OpenAIRE

    Ricardo de Melo Queiroz, Sérgio

    2003-01-01

    Ricardo de Melo Queiroz, Sérgio; de Assis Tenório Carvalho, Francisco. Group recommendation strategies based on collaborative filtering. 2003. Dissertação (Mestrado). Programa de Pós-Graduação em Ciência da Computação, Universidade Federal de Pernambuco, Recife, 2003.

  11. Process Fragment Libraries for Easier and Faster Development of Process-based Applications

    Directory of Open Access Journals (Sweden)

    David Schumm

    2011-01-01

    Full Text Available The term “process fragment” is recently gaining momentum in business process management research. We understand a process fragment as a connected and reusable process structure, which has relaxed completeness and consistency criteria compared to executable processes. We claim that process fragments allow for an easier and faster development of process-based applications. As evidence to this claim we present a process fragment concept and show a sample collection of concrete, real-world process fragments. We present advanced application scenarios for using such fragments in development of process-based applications. Process fragments are typically managed in a repository, forming a process fragment library. On top of a process fragment library from previous work, we discuss the potential impact of using process fragment libraries in cross-enterprise collaboration and application integration.

  12. Modeling of frequency agile devices: development of PKI neuromodeling library based on hierarchical network structure

    Science.gov (United States)

    Sanchez, P.; Hinojosa, J.; Ruiz, R.

    2005-06-01

    Recently, neuromodeling methods of microwave devices have been developed. These methods are suitable for the model generation of novel devices. They allow fast and accurate simulations and optimizations. However, the development of libraries makes these methods to be a formidable task, since they require massive input-output data provided by an electromagnetic simulator or measurements and repeated artificial neural network (ANN) training. This paper presents a strategy reducing the cost of library development with the advantages of the neuromodeling methods: high accuracy, large range of geometrical and material parameters and reduced CPU time. The library models are developed from a set of base prior knowledge input (PKI) models, which take into account the characteristics common to all the models in the library, and high-level ANNs which give the library model outputs from base PKI models. This technique is illustrated for a microwave multiconductor tunable phase shifter using anisotropic substrates. Closed-form relationships have been developed and are presented in this paper. The results show good agreement with the expected ones.

  13. The value of Web-based library services at Cedars-Sinai Health System.

    Science.gov (United States)

    Halub, L P

    1999-07-01

    Cedars-Sinai Medical Library/Information Center has maintained Web-based services since 1995 on the Cedars-Sinai Health System network. In that time, the librarians have found the provision of Web-based services to be a very worthwhile endeavor. Library users value the services that they access from their desktops because the services save time. They also appreciate being able to access services at their convenience, without restriction by the library's hours of operation. The library values its Web site because it brings increased visibility within the health system, and it enables library staff to expand services when budget restrictions have forced reduced hours of operation. In creating and maintaining the information center Web site, the librarians have learned the following lessons: consider the design carefully; offer what services you can, but weigh the advantages of providing the services against the time required to maintain them; make the content as accessible as possible; promote your Web site; and make friends in other departments, especially information services.

  14. Generation of one energy group cross section library with MC2 computer code

    International Nuclear Information System (INIS)

    Cunha Menezes Filho, A. da; Souza, A.L. de.

    1982-01-01

    One group temperature dependent cross sections are generated via MC 2 for Pu-242, Ni-58, Fe-56, U-235, U-238, Pu-239, Pu-240, Pu-241, Be-9 e Th-232. The influence of the buckling and the weighting functions is studied throught calculations of an important integral parameter: the critical radius. (author) [pt

  15. Medium-sized Universities Connect to Their Libraries: Links on University Home Pages and User Group Pages

    Directory of Open Access Journals (Sweden)

    Pamela Harpel-Burk

    2006-03-01

    Full Text Available From major tasks—such as recruitment of new students and staff—to the more mundane but equally important tasks—such as providing directions to campus—college and university Web sites perform a wide range of tasks for a varied assortment of users. Overlapping functions and user needs meld to create the need for a Web site with three major functions: promotion and marketing, access to online services, and providing a means of communication between individuals and groups. In turn, college and university Web sites that provide links to their library home page can be valuable assets for recruitment, public relations, and for helping users locate online services.

  16. High Energy Physics Forum for Computational Excellence: Working Group Reports (I. Applications Software II. Software Libraries and Tools III. Systems)

    Energy Technology Data Exchange (ETDEWEB)

    Habib, Salman [Argonne National Lab. (ANL), Argonne, IL (United States); Roser, Robert [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); LeCompte, Tom [Argonne National Lab. (ANL), Argonne, IL (United States); Marshall, Zach [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Borgland, Anders [SLAC National Accelerator Lab., Menlo Park, CA (United States); Viren, Brett [Brookhaven National Lab. (BNL), Upton, NY (United States); Nugent, Peter [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Asai, Makato [SLAC National Accelerator Lab., Menlo Park, CA (United States); Bauerdick, Lothar [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Finkel, Hal [Argonne National Lab. (ANL), Argonne, IL (United States); Gottlieb, Steve [Indiana Univ., Bloomington, IN (United States); Hoeche, Stefan [SLAC National Accelerator Lab., Menlo Park, CA (United States); Sheldon, Paul [Vanderbilt Univ., Nashville, TN (United States); Vay, Jean-Luc [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Elmer, Peter [Princeton Univ., NJ (United States); Kirby, Michael [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Patton, Simon [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Potekhin, Maxim [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Yanny, Brian [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Calafiura, Paolo [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Dart, Eli [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gutsche, Oliver [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Izubuchi, Taku [Brookhaven National Lab. (BNL), Upton, NY (United States); Lyon, Adam [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Petravick, Don [Univ. of Illinois, Urbana-Champaign, IL (United States). National Center for Supercomputing Applications (NCSA)

    2015-10-29

    Computing plays an essential role in all aspects of high energy physics. As computational technology evolves rapidly in new directions, and data throughput and volume continue to follow a steep trend-line, it is important for the HEP community to develop an effective response to a series of expected challenges. In order to help shape the desired response, the HEP Forum for Computational Excellence (HEP-FCE) initiated a roadmap planning activity with two key overlapping drivers -- 1) software effectiveness, and 2) infrastructure and expertise advancement. The HEP-FCE formed three working groups, 1) Applications Software, 2) Software Libraries and Tools, and 3) Systems (including systems software), to provide an overview of the current status of HEP computing and to present findings and opportunities for the desired HEP computational roadmap. The final versions of the reports are combined in this document, and are presented along with introductory material.

  17. High Energy Physics Forum for Computational Excellence: Working Group Reports (I. Applications Software II. Software Libraries and Tools III. Systems)

    Energy Technology Data Exchange (ETDEWEB)

    Habib, Salman [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Roser, Robert [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2015-10-28

    Computing plays an essential role in all aspects of high energy physics. As computational technology evolves rapidly in new directions, and data throughput and volume continue to follow a steep trend-line, it is important for the HEP community to develop an effective response to a series of expected challenges. In order to help shape the desired response, the HEP Forum for Computational Excellence (HEP-FCE) initiated a roadmap planning activity with two key overlapping drivers -- 1) software effectiveness, and 2) infrastructure and expertise advancement. The HEP-FCE formed three working groups, 1) Applications Software, 2) Software Libraries and Tools, and 3) Systems (including systems software), to provide an overview of the current status of HEP computing and to present findings and opportunities for the desired HEP computational roadmap. The final versions of the reports are combined in this document, and are presented along with introductory material.

  18. LDEF materials special investigation group's data bases

    Science.gov (United States)

    Strickland, John W.; Funk, Joan G.; Davis, John M.

    1993-01-01

    The Long Duration Exposure Facility (LDEF) was composed of and contained a wide array of materials, representing the largest collection of materials flown for space exposure and returned for ground-based analyses to date. The results and implications of the data from these materials are the foundation on which future space missions will be built. The LDEF Materials Special Investigation Group (MSIG) has been tasked with establishing and developing data bases to document these materials and their performance to assure not only that the data are archived for future generations but also that the data are available to the space user community in an easily accessed, user-friendly form. The format and content of the data bases developed or being developed to accomplish this task are discussed. The hardware and software requirements for each of the three data bases are discussed along with current availability of the data bases.

  19. Culture and group-based emotions: could group-based emotions be dialectical?

    Science.gov (United States)

    Lu, Minjie; Hamamura, Takeshi; Doosje, Bertjan; Suzuki, Satoko; Takemura, Kosuke

    2017-08-01

    Group-based emotions are experienced when individuals are engaged in emotion-provoking events that implicate the in-group. This research examines the complexity of group-based emotions, specifically a concurrence of positive and negative emotions, focusing on the role of dialecticism, or a set of folk beliefs prevalent in Asian cultures that views nature and objects as constantly changing, inherently contradictory, and fundamentally interconnected. Study 1 found that dialecticism is positively associated with the complexity of Chinese participants' group-based emotions after reading a scenario depicting a positive intergroup experience. Study 2 found that Chinese participants experienced more complex group-based emotions compared with Dutch participants in an intergroup situation and that this cultural difference was mediated by dialecticism. Study 3 manipulated dialecticism and confirmed its causal effect on complex group-based emotions. These studies also suggested the role of a balanced appraisal of an intergroup situation as a mediating factor.

  20. MOSFET-like CNFET based logic gate library for low-power application: a comparative study

    International Nuclear Information System (INIS)

    Gowri Sankar, P. A.; Udhayakumar, K.

    2014-01-01

    The next generation of logic gate devices are expected to depend upon radically new technologies mainly due to the increasing difficulties and limitations of existing CMOS technology. MOSFET like CNFETs should ideally be the best devices to work with for high-performance VLSI. This paper presents results of a comprehensive comparative study of MOSFET-like carbon nanotube field effect transistors (CNFETs) technology based logic gate library for high-speed, low-power operation than conventional bulk CMOS libraries. It focuses on comparing four promising logic families namely: complementary-CMOS (C-CMOS), transmission gate (TG), complementary pass logic (CPL) and Domino logic (DL) styles are presented. Based on these logic styles, the proposed library of static and dynamic NAND-NOR logic gates, XOR, multiplexer and full adder functions are implemented efficiently and carefully analyzed with a test bench to measure propagation delay and power dissipation as a function of supply voltage. This analysis provides the right choice of logic style for low-power, high-speed applications. Proposed logic gates libraries are simulated using Synopsys HSPICE based on the standard 32 nm CNFET model. The simulation results demonstrate that, it is best to use C-CMOS logic style gates that are implemented in CNFET technology which are superior in performance compared to other logic styles, because of their low average power-delay-product (PDP). The analysis also demonstrates how the optimum supply voltage varies with logic styles in ultra-low power systems. The robustness of the proposed logic gate library is also compared with conventional and state-art of CMOS logic gate libraries. (semiconductor integrated circuits)

  1. Activity-Based Costing (ABC and Time-Driven Activity-Based Costing (TDABC: Applicable Methods for University Libraries?

    Directory of Open Access Journals (Sweden)

    Kate-Riin Kont

    2011-01-01

    Full Text Available Objective – This article provides an overview of how university libraries research and adapt new cost accounting models, such as “activity-based costing” (ABC and “time-driven activity-based costing” (TDABC, focusing on the strengths and weaknesses of both methods to determine which of these two is suitable for application in university libraries.Methods – This paper reviews and summarizes the literature on cost accounting and costing practices of university libraries. A brief overview of the history of cost accounting, costing, and time and motion studies in libraries is also provided. The ABC and the TDABC method, designed as a revised and easier version of the ABC by Kaplan and Anderson (Kaplan & Anderson 2004 at the beginning of the 21st century, as well as the adoption and adaptation of these methods by university libraries are described, and their strengths and weaknesses, as well as their suitability for university libraries, are analyzed. Results – Cost accounting and costing studies in libraries have a long history, the first of these dating back to 1877. The development of cost accounting and time and motion studies can be seen as a natural evolution of techniques which were created to solve management problems. The ABC method is the best-known management accounting innovation of the last 20 years, and is already widely used in university libraries around the world. However, setting up an ABC system can be very costly, and the system needs to be regularly updated, which further increases its costs. The TDABC system can not only be implemented more quickly (and thus more cheaply, but also can be updated more easily than the traditional ABC, which makes the TDABC the more suitable method for university libraries.Conclusion – Both methods are suitable for university libraries. However, the ABC method can only be implemented in collaboration with an accounting department. The TDABC method can be tested and implemented by

  2. Time-Based Way Finding at the Library of Agriculture Information and Scientific Documents Center (ASIDC

    Directory of Open Access Journals (Sweden)

    Roya Pournaghi

    2017-09-01

    The illustrated maps had shown that they might be helpful in gaining a better understanding of the users’ access to the library entrance and facilities in order to improve its utility and efficiency. This is a new idea started to be used in the libraries of the world. Since the study dealing with the network traffic and the amount of time for non-negative ways, Dijkstra’s algorithm was used to Time-Based Way finding. After creating the database, determining the shortest path at the least time was possible.

  3. Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective.

    Science.gov (United States)

    Bauer, Renato A; Wurst, Jacqueline M; Tan, Derek S

    2010-06-01

    Existing drugs address a relatively narrow range of biological targets. As a result, libraries of drug-like molecules have proven ineffective against a variety of challenging targets, such as protein-protein interactions, nucleic acid complexes, and antibacterial modalities. In contrast, natural products are known to be effective at modulating such targets, and new libraries are being developed based on underrepresented scaffolds and regions of chemical space associated with natural products. This has led to several recent successes in identifying new chemical probes that address these challenging targets. Copyright 2010 Elsevier Ltd. All rights reserved.

  4. A virtualized software based on the NVIDIA cuFFT library for image denoising: performance analysis

    DEFF Research Database (Denmark)

    Galletti, Ardelio; Marcellino, Livia; Montella, Raffaele

    2017-01-01

    Abstract Generic Virtualization Service (GVirtuS) is a new solution for enabling GPGPU on Virtual Machines or low powered devices. This paper focuses on the performance analysis that can be obtained using a GPGPU virtualized software. Recently, GVirtuS has been extended in order to support CUDA...... ancillary libraries with good results. Here, our aim is to analyze the applicability of this powerful tool to a real problem, which uses the NVIDIA cuFFT library. As case study we consider a simple denoising algorithm, implementing a virtualized GPU-parallel software based on the convolution theorem...

  5. Teaching Electronic Literacy A Concepts-Based Approach for School Library Media Specialists

    CERN Document Server

    Craver, Kathleen W

    1997-01-01

    School library media specialists will find this concepts-based approach to teaching electronic literacy an indispensable basic tool for instructing students and teachers. It provides step-by-step instruction on how to find and evaluate needed information from electronic databases and the Internet, how to formulate successful electronic search strategies and retrieve relevant results, and how to interpret and critically analyze search results. The chapters contain a suggested lesson plan and sample assignments for the school library media specialist to use in teaching electronic literacy skills

  6. Developing Applications in the Era of Cloud-based SaaS Library Systems

    Directory of Open Access Journals (Sweden)

    Josh Weisman

    2014-10-01

    Full Text Available As the move to cloud-based SaaS library systems accelerates, we must consider what it means to develop applications when the core of the system isn't under the library's control. The entire application lifecycle is changing, from development to testing to production. Developing applications for cloud solutions raises new concerns, such as security, multi-tenancy, latency, and analytics. In this article, we review the landscape and suggest a view of how to be successful for the benefit of library staff and end-users in this new reality. We discuss what kinds of APIs and protocols vendors should be supporting, and suggest how best to take advantage of the innovations being introduced.

  7. Investigating the Use of a Digital Library in an Inquiry-Based Undergraduate Geology Course

    Science.gov (United States)

    Apedoe, Xornam S.

    2007-01-01

    This paper reports the findings of a qualitative research study designed to investigate the opportunities and obstacles presented by a digital library for supporting teaching and learning in an inquiry-based undergraduate geology course. Data for this study included classroom observations and field-notes of classroom practices, questionnaires, and…

  8. Improving conditions for reuse of design solutions - by means of a context based solution library

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Grothe-Møller, Thorkild; Andreasen, Mogens Myrup

    1997-01-01

    Among the most important reasoning mechanisms in design is reasoning by analogy. One precondition for being able to reason about the properties and functionalitues of a product or subsystem is that the context of the solution is known. This paper presents a computer based solution library where...

  9. Speakeasy Studio and Cafe: Information Literacy, Web-based Library Instruction, and Technology.

    Science.gov (United States)

    Jacobs, Mark

    2001-01-01

    Discussion of academic library instruction and information literacy focuses on a Web-based program developed at Washington State University called Speakeasy Studio and Cafe that is used for bibliographic instruction. Highlights include the research process; asking the right question; and adapting to students' differing learning styles. (LRW)

  10. When are emotions related to group-based appraisals? A comparison between group-based emotions and general group emotions.

    Science.gov (United States)

    Kuppens, Toon; Yzerbyt, Vincent Y

    2014-12-01

    In the literature on emotions in intergroup relations, it is not always clear how exactly emotions are group-related. Here, we distinguish between emotions that involve appraisals of immediate group concerns (i.e., group-based emotions) and emotions that do not. Recently, general group emotions, measured by asking people how they feel "as a group member" but without specifying an object for these emotions, have been conceptualized as reflecting appraisals of group concerns. In contrast, we propose that general group emotions are best seen as emotions about belonging to a group. In two studies, general group emotions were closely related to emotions that are explicitly measured as belonging emotions. Two further studies showed that general group emotions were not related to appraisals of immediate group concerns, whereas group-based emotions were. We argue for more specificity regarding the group-level aspects of emotion that are tapped by emotion measures. © 2014 by the Society for Personality and Social Psychology, Inc.

  11. Construction of naïve camelids VHH repertoire in phage display-based library.

    Science.gov (United States)

    Sabir, Jamal S M; Atef, Ahmed; El-Domyati, Fotouh M; Edris, Sherif; Hajrah, Nahid; Alzohairy, Ahmed M; Bahieldin, Ahmed

    2014-04-01

    Camelids have unique antibodies, namely HCAbs (VHH) or commercially named Nanobodies(®) (Nb) that are composed only of a heavy-chain homodimer. As libraries based on immunized camelids are time-consuming, costly and likely redundant for certain antigens, we describe the construction of a naïve camelid VHHs library from blood serum of non-immunized camelids with affinity in the subnanomolar range and suitable for standard immune applications. This approach is rapid and recovers VHH repertoire with the advantages of being more diverse, non-specific and devoid of subpopulations of specific antibodies, which allows the identification of binders for any potential antigen (or pathogen). RNAs from a number of camelids from Saudi Arabia were isolated and cDNAs of the diverse vhh gene were amplified; the resulting amplicons were cloned in the phage display pSEX81 vector. The size of the library was found to be within the required range (10(7)) suitable for subsequent applications in disease diagnosis and treatment. Two hundred clones were randomly selected and the inserted gene library was either estimated for redundancy or sequenced and aligned to the reference camelid vhh gene (acc. No. ADE99145). Results indicated complete non-specificity of this small library in which no single event of redundancy was detected. These results indicate the efficacy of following this approach in order to yield a large and diverse enough gene library to secure the presence of the required version encoding the required antibodies for any target antigen. This work is a first step towards the construction of phage display-based biosensors useful in disease (e.g., TB or tuberculosis) diagnosis and treatment. Copyright © 2014 Académie des sciences. Published by Elsevier SAS. All rights reserved.

  12. Assessing high affinity binding to HLA-DQ2.5 by a novel peptide library based approach

    DEFF Research Database (Denmark)

    Jüse, Ulrike; Arntzen, Magnus; Højrup, Peter

    2011-01-01

    Here we report on a novel peptide library based method for HLA class II binding motif identification. The approach is based on water soluble HLA class II molecules and soluble dedicated peptide libraries. A high number of different synthetic peptides are competing to interact with a limited amount...... library. The eluted sequences fit very well with the previously described HLA-DQ2.5 peptide binding motif. This novel method, limited by library complexity and sensitivity of mass spectrometry, allows the analysis of several thousand synthetic sequences concomitantly in a simple water soluble format....

  13. An Academic Library's Experience with Fee-Based Services.

    Science.gov (United States)

    Hornbeck, Julia W.

    1983-01-01

    Profile of fee-based information services offered by the Information Exchange Center of Georgia Institute of Technology notes history and background, document delivery to commercial clients and on-campus faculty, online and manual literature searching, staff, cost analysis, fee schedule, operating methods, client relations, marketing, and current…

  14. Academic Job Placements in Library and Information Science Field: A Case Study Performed on ALISE Web-Based Postings

    Science.gov (United States)

    Abouserie, Hossam Eldin Mohamed Refaat

    2010-01-01

    The study investigated and analyzed the state of academic web-based job announcements in Library and Information Science Field. The purpose of study was to get in depth understanding about main characteristics and trends of academic job market in Library and Information science field. The study focused on web-based version announcement as it was…

  15. MpTheory Java library: a multi-platform Java library for systems biology based on the Metabolic P theory.

    Science.gov (United States)

    Marchetti, Luca; Manca, Vincenzo

    2015-04-15

    MpTheory Java library is an open-source project collecting a set of objects and algorithms for modeling observed dynamics by means of the Metabolic P (MP) theory, that is, a mathematical theory introduced in 2004 for modeling biological dynamics. By means of the library, it is possible to model biological systems both at continuous and at discrete time. Moreover, the library comprises a set of regression algorithms for inferring MP models starting from time series of observations. To enhance the modeling experience, beside a pure Java usage, the library can be directly used within the most popular computing environments, such as MATLAB, GNU Octave, Mathematica and R. The library is open-source and licensed under the GNU Lesser General Public License (LGPL) Version 3.0. Source code, binaries and complete documentation are available at http://mptheory.scienze.univr.it. luca.marchetti@univr.it, marchetti@cosbi.eu Supplementary data are available at Bioinformatics online. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  16. Collection-based analysis of selected medical libraries in the Philippines using Doody’s Core Titles

    Directory of Open Access Journals (Sweden)

    Efren Torres Jr., MLIS

    2017-01-01

    Conclusion: De La Salle Health Sciences Institute and University of Santo Tomas had sound medical collections based on Doody’s Core Titles. Collectively, the medical libraries shared common collection development priorities, as evidenced by similarities in strong areas. Library budget and the role of the library director in book selection were among the factors that could contributed to a high percentage of match titles.

  17. Design and implementation of universal mathematical library supporting algorithm development for FPGA based systems in high energy physics experiments

    International Nuclear Information System (INIS)

    Jalmuzna, W.

    2006-02-01

    The X-ray free-electron laser XFEL that is being planned at the DESY research center in cooperation with European partners will produce high-intensity ultra-short Xray flashes with the properties of laser light. This new light source, which can only be described in terms of superlatives, will open up a whole range of new perspectives for the natural sciences. It could also offer very promising opportunities for industrial users. SIMCON (SIMulator and CONtroller) is the project of the fast, low latency digital controller dedicated for LLRF system in VUV FEL experiment based on modern FPGA chips It is being developed by ELHEP group in Institute of Electronic Systems at Warsaw University of Technology. The main purpose of the project is to create a controller for stabilizing the vector sum of fields in cavities of one cryomodule in the experiment. The device can be also used as the simulator of the cavity and testbench for other devices. Flexibility and computation power of this device allow implementation of fast mathematical algorithms. This paper describes the concept, implementation and tests of universal mathematical library for FPGA algorithm implementation. It consists of many useful components such as IQ demodulator, division block, library for complex and floating point operations, etc. It is able to speed up implementation time of many complicated algorithms. Library have already been tested using real accelerator signals and the performance achieved is satisfactory. (Orig.)

  18. Design and implementation of universal mathematical library supporting algorithm development for FPGA based systems in high energy physics experiments

    Energy Technology Data Exchange (ETDEWEB)

    Jalmuzna, W.

    2006-02-15

    The X-ray free-electron laser XFEL that is being planned at the DESY research center in cooperation with European partners will produce high-intensity ultra-short Xray flashes with the properties of laser light. This new light source, which can only be described in terms of superlatives, will open up a whole range of new perspectives for the natural sciences. It could also offer very promising opportunities for industrial users. SIMCON (SIMulator and CONtroller) is the project of the fast, low latency digital controller dedicated for LLRF system in VUV FEL experiment based on modern FPGA chips It is being developed by ELHEP group in Institute of Electronic Systems at Warsaw University of Technology. The main purpose of the project is to create a controller for stabilizing the vector sum of fields in cavities of one cryomodule in the experiment. The device can be also used as the simulator of the cavity and testbench for other devices. Flexibility and computation power of this device allow implementation of fast mathematical algorithms. This paper describes the concept, implementation and tests of universal mathematical library for FPGA algorithm implementation. It consists of many useful components such as IQ demodulator, division block, library for complex and floating point operations, etc. It is able to speed up implementation time of many complicated algorithms. Library have already been tested using real accelerator signals and the performance achieved is satisfactory. (Orig.)

  19. Visibility of Open Acces Repositories of Digital University Libraries: A Case Study of the EU Visegrád Group

    Directory of Open Access Journals (Sweden)

    Erzsebet Dani

    2014-04-01

    Full Text Available For scientific research institutions, as well as for scientists individually, the degree of accessibility of a given institution's and of an individual researcher's scientific achievement is of growing significance in this world of the internet: i.e., it is vitally important to know about and to have easy access to what research is conducted in what fields and with what results in the different institutions. In this study I intend to survey the present situation concerning the homepages of leading universities of the so-called Visegrad Group inside the European Union and the extent to which the present situation serves or fails to serve the cause of the philosophy of open access. My aim is twofold. (1 I will consider whether the scienetific-knowledge repositories built by universities are accessible or not, and/or how easy or difficult it is to access them. Provided that those repositories exist at all, because, in spite of the fact that the Berlin Declaration is generally adopted in principle, the homepages of a good number of the surveyed Visegrad Group universities or libraries do not make their research databases easily accessible or accessible at all, or they can be accessed in the given national language only. (2[1] http://openaccess.mpg.de/286432/Berlin-Declaration [09.18.2013.] [2] https://www.openaire.eu/en/contact-us/partners

  20. Comparative analysis of machine learning methods in ligand-based virtual screening of large compound libraries.

    Science.gov (United States)

    Ma, Xiao H; Jia, Jia; Zhu, Feng; Xue, Ying; Li, Ze R; Chen, Yu Z

    2009-05-01

    Machine learning methods have been explored as ligand-based virtual screening tools for facilitating drug lead discovery. These methods predict compounds of specific pharmacodynamic, pharmacokinetic or toxicological properties based on their structure-derived structural and physicochemical properties. Increasing attention has been directed at these methods because of their capability in predicting compounds of diverse structures and complex structure-activity relationships without requiring the knowledge of target 3D structure. This article reviews current progresses in using machine learning methods for virtual screening of pharmacodynamically active compounds from large compound libraries, and analyzes and compares the reported performances of machine learning tools with those of structure-based and other ligand-based (such as pharmacophore and clustering) virtual screening methods. The feasibility to improve the performance of machine learning methods in screening large libraries is discussed.

  1. The Research and Education of Evidence Based Library and Information Practice; A Narrative Review

    Directory of Open Access Journals (Sweden)

    Vahideh Zareh Gavgani

    2018-01-01

    Full Text Available Background and Objectives: Evidence based librarianship (EBL was defined as “use of best available evidence from qualitative and quantitative research results and rational experience and decisions acquired from the daily practice of library”. However there are controversies about if the nature of EBL deals with library services or professional practice and if it needs a formal education or informal continuing education is enough? To shed light on this ambiguity, the aim of this study was to find out the state-of-the-art of education of EBL in the world. Material and Methods: The study utilized library and documentation methods to investigate the academic education of EBL through review of the available literature and websites. Results: The findings of the study revealed that evidence based librarianship does have formal curriculum for academic education in post graduate levels (post master and master. It also revealed that “Evidence Based Approach” (EBA and “Evidence Based Medicine” (EBM were also similar courses that are offered in Master and PhD levels. Conclusion: Based on the history and revolution of EBA, it is time to develop formal curriculum and field of study for Evidence Based Information Practice. This study suggests establishment of the academic field of Evidence Based and Information Science to overcome the problems and limitations that library science faces in practice.

  2. Extension and improvement of the FENDL library for fusion applications (FENDL-2). Report of an IAEA advisory group meeting

    International Nuclear Information System (INIS)

    Herman, M.; Pashchenko, A.B.

    1997-09-01

    The present report contains the summary of the IAEA Advisory Meeting on Extension and Improvement of the Fusion Evaluated Nuclear Data Library (FENDL), organized by IAEA Nuclear Data Section and held in IAEA headquarters in Vienna from 3 to 7 March 1997. The FENDL library is a comprehensive collection of high-quality nuclear data, selected from the various existing national data libraries, covering the necessary input for physics and engineering studies of the material development, design, operation and safety of ITER and other fusion devices. The library has undergone an intensive testing and validation against integral benchmarks. The main scope of the Meeting was to discuss recent developments within FENDL project, review new evaluations to be included in the library, and decide on the release of the second version of the library (FENDL-2.0). During the meeting it was demonstrated that the FENDL-2.0 library shows a net improvement over the preceding FENDL-1. The release of the Library was authorized with the exception of the general purpose field FENDL/E-2.0 and its processed form, which is scheduled at the end of 1997. (author)

  3. ANSL-V: ENDF/B-V based multigroup cross-section libraries for Advanced Neutron Source (ANS) reactor studies

    International Nuclear Information System (INIS)

    Ford, W.E. III; Arwood, J.W.; Greene, N.M.; Petrie, L.M.; Primm, R.T. III; Waddell, M.W.; Webster, C.C.; Westfall, R.M.; Wright, R.Q.

    1987-01-01

    Multigroup P3 neutron, P0-P3 secondary gamma ray production (SGRP), and P6 gamma ray interaction (GRI) cross section libraries have been generated to support design work on the Advanced Neutron Source (ANS) reactor. The libraries, designated ANSL-V (Advanced Neutron Source Cross-Section Libraries), are data bases in a format suitable for subsequent generation of problem dependent cross sections. The ANSL-V libraries are available on magnetic tape from the Radiation Shielding Information Center at Oak Ridge National Laboratory

  4. Kinematic source inversions of teleseismic data based on the QUESO library for uncertainty quantification and prediction

    Science.gov (United States)

    Zielke, O.; McDougall, D.; Mai, P. M.; Babuska, I.

    2014-12-01

    One fundamental aspect of seismic hazard mitigation is gaining a better understanding of the rupture process. Because direct observation of the relevant parameters and properties is not possible, other means such as kinematic source inversions are used instead. By constraining the spatial and temporal evolution of fault slip during an earthquake, those inversion approaches may enable valuable insights in the physics of the rupture process. However, due to the underdetermined nature of this inversion problem (i.e., inverting a kinematic source model for an extended fault based on seismic data), the provided solutions are generally non-unique. Here we present a statistical (Bayesian) inversion approach based on an open-source library for uncertainty quantification (UQ) called QUESO that was developed at ICES (UT Austin). The approach has advantages with respect to deterministic inversion approaches as it provides not only a single (non-unique) solution but also provides uncertainty bounds with it. Those uncertainty bounds help to qualitatively and quantitatively judge how well constrained an inversion solution is and how much rupture complexity the data reliably resolve. The presented inversion scheme uses only tele-seismically recorded body waves but future developments may lead us towards joint inversion schemes. After giving an insight in the inversion scheme ifself (based on delayed rejection adaptive metropolis, DRAM) we explore the method's resolution potential. For that, we synthetically generate tele-seismic data, add for example different levels of noise and/or change fault plane parameterization and then apply our inversion scheme in the attempt to extract the (known) kinematic rupture model. We conclude with exemplary inverting real tele-seismic data of a recent large earthquake and compare those results with deterministically derived kinematic source models provided by other research groups.

  5. Generation of seven group cross section library for TRIGA LEU fuel in CITATION format and benchmarking some experimental and operational data

    International Nuclear Information System (INIS)

    Sarker, M.M.; Bhuiyan, S.I.; Akramuzzaman, M.

    2007-01-01

    The principal objective of this study is to validate the seven group cross section library in CITATION format for TRIGA LEU Fuel. This presentation deals with the 'generation of a cross section library for the CITATION and its validation. We used WIMSD-5B version for the generation of all group constants. The overall strategy is: (1) use WIMS package to generate few group neutron macroscopic cross section (cell constants) for all of the materials in the core and its immediate neighborhood (2) use 3-D code CITATION to perform the global analysis of the core to study: multiplication factor, neutron flux distribution and power peaking factors. Various options available in WIMS program were studied in depth to finalize the models to generate the most appropriate group constants. For the global analysis the code CITATION and a post processing program FCAP were chosen. Thus a seven group cross section library for the calculations of TRIGA Research Reactor was generated. To investigate the validity of the generated library a critical experiment of the TRIGA research reactor was benchmarked. (author)

  6. FilTer BaSe: A web accessible chemical database for small compound libraries.

    Science.gov (United States)

    Kolte, Baban S; Londhe, Sanjay R; Solanki, Bhushan R; Gacche, Rajesh N; Meshram, Rohan J

    2018-03-01

    Finding novel chemical agents for targeting disease associated drug targets often requires screening of large number of new chemical libraries. In silico methods are generally implemented at initial stages for virtual screening. Filtering of such compound libraries on physicochemical and substructure ground is done to ensure elimination of compounds with undesired chemical properties. Filtering procedure, is redundant, time consuming and requires efficient bioinformatics/computer manpower along with high end software involving huge capital investment that forms a major obstacle in drug discovery projects in academic setup. We present an open source resource, FilTer BaSe- a chemoinformatics platform (http://bioinfo.net.in/filterbase/) that host fully filtered, ready to use compound libraries with workable size. The resource also hosts a database that enables efficient searching the chemical space of around 348,000 compounds on the basis of physicochemical and substructure properties. Ready to use compound libraries and database presented here is expected to aid a helping hand for new drug developers and medicinal chemists. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Affinity-based screening of combinatorial libraries using automated, serial-column chromatography

    Energy Technology Data Exchange (ETDEWEB)

    Evans, D.M.; Williams, K.P.; McGuinness, B. [PerSeptive Biosystems, Framingham, MA (United States)] [and others

    1996-04-01

    The authors have developed an automated serial chromatographic technique for screening a library of compounds based upon their relative affinity for a target molecule. A {open_quotes}target{close_quotes} column containing the immobilized target molecule is set in tandem with a reversed-phase column. A combinatorial peptide library is injected onto the target column. The target-bound peptides are eluted from the first column and transferred automatically to the reversed-phase column. The target-specific peptide peaks from the reversed-phase column are identified and sequenced. Using a monoclonal antibody (3E-7) against {beta}-endorphin as a target, we selected a single peptide with sequence YGGFL from approximately 5800 peptides present in a combinatorial library. We demonstrated the applicability of the technology towards selection of peptides with predetermined affinity for bacterial lipopolysaccharide (LPS, endotoxin). We expect that this technology will have broad applications for high throughput screening of chemical libraries or natural product extracts. 21 refs., 4 figs.

  8. ZZ-FSXLIB-JD99, MCNP nuclear data library based on JENDL Dosimetry File 99

    International Nuclear Information System (INIS)

    Shibata, Keiichi

    2007-01-01

    Description: JENDL Dosimetry File 99 processed into ACE for Monte Carlo calculations. JENDL/D-99 based MCNP library. Format: ACE. Number of groups: Continuous energy cross section library. Nuclides: 47 Nuclides and 67 reactions: Li-6 (n, triton) alpha; Li-6 alpha-production; Li-7 triton- production; B-10 (n, alpha) Li-7; B-10 alpha-production; F-19 (n, 2n) F-18; Na-23 (n, 2n) Na-22; Na-23 (n, gamma) Na-24; Mg-24 (n, p) Na-24; Al-27 (n, p) Mg-27; Al-27 (n, alpha) Na-24; P-31 (n, p) Si-31; S-32 (n, p) P-32; Sc-45 (n, gamma) Sc-46; Ti-nat (n, x) Sc-46; Ti-nat (n, x) Sc-47; Ti-nat (n, x) Sc-48; Ti-46 (n, 2n) Ti-45; Ti-46 (n, p) Sc-46; Ti-47 (n, np) Sc-46; Ti-47 (n, p) Sc-47; Ti-48 (n, np) Sc-47; Ti-48 (n, p) Sc-48; Ti-49 (n, np) Sc-48; Cr-50 (n, gamma) Cr-51; Cr-52 (n, 2n) Cr-51; Mn-55 (n, 2n) Mn-54; Mn-55 (n, gamma) Mn-56; Fe-54 (n, p) Mn-54; Fe-56 (n, p) Mn-56; Fe-57 (n, np) Mn-56; Fe-58 (n, gamma) Fe-59; Co-59 (n, 2n) Co-58; Co-59 (n, gamma) Co-60; Co-59 (n, alpha) Mn-56; Ni-58 (n, 2n) Ni-57; Ni-58 (n, p) Co-58; Ni-60 (n, p) Co-60; Cu-63 (n, 2n) Cu-62; Cu-63 (n, gamma) Cu-64; Cu-63 (n, alpha) Co-60; Cu-65 (n, 2n) Cu-64; Zn-64 (n, p) Cu-64; Y-89 (n, 2n) Y-88; Zr-90 (n, 2n) Zr-89; Nb-93 (n, n') Nb-93m; Nb-93 (n, 2n) Nb-92m; Rh-103 (n, n') Rh-103m; Ag-109 (n, gamma) Ag-110m; In-115 (n, n') In-115m; In-115 (n, gamma) In-116m; I-127 (n,2n) I-126; Eu-151 (n, gamma) Eu-152; Tm-169 (n,2n) Tm-168; Ta-181 (n, gamma) Ta-182; W-186 (n, gamma) W-187; Au-197 (n, 2n) Au-196; Au-197 (n, gamma) Au-198; Hg-199 (n, n') Hg-199m; Th-232 - fission; Th-232 (n, gamma) Th-233; U-235 - fission; U-238 - fission; U-238 (n, gamma) U-239; Np-237 - fission; Pu-239 - fission; Am-241 - fission. The data were produced on the 31 of March, 2006

  9. The mathematics of a successful deconvolution: a quantitative assessment of mixture-based combinatorial libraries screened against two formylpeptide receptors.

    Science.gov (United States)

    Santos, Radleigh G; Appel, Jon R; Giulianotti, Marc A; Edwards, Bruce S; Sklar, Larry A; Houghten, Richard A; Pinilla, Clemencia

    2013-05-30

    In the past 20 years, synthetic combinatorial methods have fundamentally advanced the ability to synthesize and screen large numbers of compounds for drug discovery and basic research. Mixture-based libraries and positional scanning deconvolution combine two approaches for the rapid identification of specific scaffolds and active ligands. Here we present a quantitative assessment of the screening of 32 positional scanning libraries in the identification of highly specific and selective ligands for two formylpeptide receptors. We also compare and contrast two mixture-based library approaches using a mathematical model to facilitate the selection of active scaffolds and libraries to be pursued for further evaluation. The flexibility demonstrated in the differently formatted mixture-based libraries allows for their screening in a wide range of assays.

  10. Time-Driven Activity-Based Costing for Inter-Library Services: A Case Study in a University

    Science.gov (United States)

    Pernot, Eli; Roodhooft, Filip; Van den Abbeele, Alexandra

    2007-01-01

    Although the true costs of inter-library loans (ILL) are unknown, universities increasingly rely on them to provide better library services at lower costs. Through a case study, we show how to perform a time-driven activity-based costing analysis of ILL and provide evidence of the benefits of such an analysis.

  11. IDENTIFICATION OF ACTIVE BACTERIAL COMMUNITIES IN A MODEL DRINKING WATER BIOFILM SYSTEM USING 16S RRNA-BASED CLONE LIBRARIES

    Science.gov (United States)

    Recent phylogenetic studies have used DNA as the target molecule for the development of environmental 16S rDNA clone libraries. As DNA may persist in the environment, DNA-based libraries cannot be used to identify metabolically active bacteria in water systems. In this study, a...

  12. From cheminformatics to structure-based design: Web services and desktop applications based on the NAOMI library.

    Science.gov (United States)

    Bietz, Stefan; Inhester, Therese; Lauck, Florian; Sommer, Kai; von Behren, Mathias M; Fährrolfes, Rainer; Flachsenberg, Florian; Meyder, Agnes; Nittinger, Eva; Otto, Thomas; Hilbig, Matthias; Schomburg, Karen T; Volkamer, Andrea; Rarey, Matthias

    2017-11-10

    Nowadays, computational approaches are an integral part of life science research. Problems related to interpretation of experimental results, data analysis, or visualization tasks highly benefit from the achievements of the digital era. Simulation methods facilitate predictions of physicochemical properties and can assist in understanding macromolecular phenomena. Here, we will give an overview of the methods developed in our group that aim at supporting researchers from all life science areas. Based on state-of-the-art approaches from structural bioinformatics and cheminformatics, we provide software covering a wide range of research questions. Our all-in-one web service platform ProteinsPlus (http://proteins.plus) offers solutions for pocket and druggability prediction, hydrogen placement, structure quality assessment, ensemble generation, protein-protein interaction classification, and 2D-interaction visualization. Additionally, we provide a software package that contains tools targeting cheminformatics problems like file format conversion, molecule data set processing, SMARTS editing, fragment space enumeration, and ligand-based virtual screening. Furthermore, it also includes structural bioinformatics solutions for inverse screening, binding site alignment, and searching interaction patterns across structure libraries. The software package is available at http://software.zbh.uni-hamburg.de. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  13. Growing Competition for Libraries.

    Science.gov (United States)

    Gibbons, Susan

    2001-01-01

    Describes the Questia subscription-based online academic digital books library. Highlights include weaknesses of the collection; what college students want from a library; importance of marketing; competition for traditional academic libraries that may help improve library services; and the ability of Questia to overcome barriers and…

  14. Digital Ethnography: Library Web Page Redesign among Digital Natives

    Science.gov (United States)

    Klare, Diane; Hobbs, Kendall

    2011-01-01

    Presented with an opportunity to improve Wesleyan University's dated library home page, a team of librarians employed ethnographic techniques to explore how its users interacted with Wesleyan's current library home page and web pages in general. Based on the data that emerged, a group of library staff and members of the campus' information…

  15. Validation of SCALE 4.0 -- CSAS25 module and the 27-group ENDF/B-IV cross-section library for low-enriched uranium systems

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, W.C.

    1993-02-01

    A version of KENO V.a and the 27-group library in SCALE-4.0 were validated for use in evaluating the nuclear criticality safety of low-enriched uranium systems. A total of 59 critical systems were analyzed. A statistical analysis of the results was performed, and subcritical acceptanced criteria are established.

  16. Validation of SCALE 4. 0 -- CSAS25 module and the 27-group ENDF/B-IV cross-section library for low-enriched uranium systems

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, W.C.

    1993-02-01

    A version of KENO V.a and the 27-group library in SCALE-4.0 were validated for use in evaluating the nuclear criticality safety of low-enriched uranium systems. A total of 59 critical systems were analyzed. A statistical analysis of the results was performed, and subcritical acceptanced criteria are established.

  17. Library based x-ray scatter correction for dedicated cone beam breast CT

    International Nuclear Information System (INIS)

    Shi, Linxi; Zhu, Lei; Vedantham, Srinivasan; Karellas, Andrew

    2016-01-01

    Purpose: The image quality of dedicated cone beam breast CT (CBBCT) is limited by substantial scatter contamination, resulting in cupping artifacts and contrast-loss in reconstructed images. Such effects obscure the visibility of soft-tissue lesions and calcifications, which hinders breast cancer detection and diagnosis. In this work, we propose a library-based software approach to suppress scatter on CBBCT images with high efficiency, accuracy, and reliability. Methods: The authors precompute a scatter library on simplified breast models with different sizes using the GEANT4-based Monte Carlo (MC) toolkit. The breast is approximated as a semiellipsoid with homogeneous glandular/adipose tissue mixture. For scatter correction on real clinical data, the authors estimate the breast size from a first-pass breast CT reconstruction and then select the corresponding scatter distribution from the library. The selected scatter distribution from simplified breast models is spatially translated to match the projection data from the clinical scan and is subtracted from the measured projection for effective scatter correction. The method performance was evaluated using 15 sets of patient data, with a wide range of breast sizes representing about 95% of general population. Spatial nonuniformity (SNU) and contrast to signal deviation ratio (CDR) were used as metrics for evaluation. Results: Since the time-consuming MC simulation for library generation is precomputed, the authors’ method efficiently corrects for scatter with minimal processing time. Furthermore, the authors find that a scatter library on a simple breast model with only one input parameter, i.e., the breast diameter, sufficiently guarantees improvements in SNU and CDR. For the 15 clinical datasets, the authors’ method reduces the average SNU from 7.14% to 2.47% in coronal views and from 10.14% to 3.02% in sagittal views. On average, the CDR is improved by a factor of 1.49 in coronal views and 2.12 in sagittal

  18. Library based x-ray scatter correction for dedicated cone beam breast CT

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Linxi; Zhu, Lei, E-mail: leizhu@gatech.edu [Nuclear and Radiological Engineering and Medical Physics Programs, The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States); Vedantham, Srinivasan; Karellas, Andrew [Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655 (United States)

    2016-08-15

    Purpose: The image quality of dedicated cone beam breast CT (CBBCT) is limited by substantial scatter contamination, resulting in cupping artifacts and contrast-loss in reconstructed images. Such effects obscure the visibility of soft-tissue lesions and calcifications, which hinders breast cancer detection and diagnosis. In this work, we propose a library-based software approach to suppress scatter on CBBCT images with high efficiency, accuracy, and reliability. Methods: The authors precompute a scatter library on simplified breast models with different sizes using the GEANT4-based Monte Carlo (MC) toolkit. The breast is approximated as a semiellipsoid with homogeneous glandular/adipose tissue mixture. For scatter correction on real clinical data, the authors estimate the breast size from a first-pass breast CT reconstruction and then select the corresponding scatter distribution from the library. The selected scatter distribution from simplified breast models is spatially translated to match the projection data from the clinical scan and is subtracted from the measured projection for effective scatter correction. The method performance was evaluated using 15 sets of patient data, with a wide range of breast sizes representing about 95% of general population. Spatial nonuniformity (SNU) and contrast to signal deviation ratio (CDR) were used as metrics for evaluation. Results: Since the time-consuming MC simulation for library generation is precomputed, the authors’ method efficiently corrects for scatter with minimal processing time. Furthermore, the authors find that a scatter library on a simple breast model with only one input parameter, i.e., the breast diameter, sufficiently guarantees improvements in SNU and CDR. For the 15 clinical datasets, the authors’ method reduces the average SNU from 7.14% to 2.47% in coronal views and from 10.14% to 3.02% in sagittal views. On average, the CDR is improved by a factor of 1.49 in coronal views and 2.12 in sagittal

  19. gLibrary/DRI: A grid-based platform to host multiple repositories for digital content

    International Nuclear Information System (INIS)

    Calanducci, A.; Gonzalez Martin, J. M.; Ramos Pollan, R.; Rubio del Solar, M.; Tcaci, S.

    2007-01-01

    In this work we present the gLibrary/DRI (Digital Repositories Infrastructure) platform. gLibrary/DRI extends gLibrary, a system with a easy-to-use web front-end designed to save and organize multimedia assets on Grid-based storage resources. The main goal of the extended platform is to reduce the cost in terms of time and effort that a repository provider spends to get its repository deployed. This is achieved by providing a common infrastructure and a set of mechanisms (APIs and specifications) that the repository providers use to define the data model, the access to the content (by navigation trees and filters) and the storage model. DRI offers a generic way to provide all this functionality; nevertheless the providers can add specific behaviours to the default functions for their repositories. The architecture is Grid based (VO system, data federation and distribution, computing power, etc). A working example based on a mammograms repository is also presented. (Author)

  20. CSBB-ConeExclusion, adapting structure based solution virtual screening to libraries on solid support.

    Science.gov (United States)

    Shave, Steven; Auer, Manfred

    2013-12-23

    Combinatorial chemical libraries produced on solid support offer fast and cost-effective access to a large number of unique compounds. If such libraries are screened directly on-bead, the speed at which chemical space can be explored by chemists is much greater than that addressable using solution based synthesis and screening methods. Solution based screening has a large supporting body of software such as structure-based virtual screening tools which enable the prediction of protein-ligand complexes. Use of these techniques to predict the protein bound complexes of compounds synthesized on solid support neglects to take into account the conjugation site on the small molecule ligand. This may invalidate predicted binding modes, the linker may be clashing with protein atoms. We present CSBB-ConeExclusion, a methodology and computer program which provides a measure of the applicability of solution dockings to solid support. Output is given in the form of statistics for each docking pose, a unique 2D visualization method which can be used to determine applicability at a glance, and automatically generated PyMol scripts allowing visualization of protein atom incursion into a defined exclusion volume. CSBB-ConeExclusion is then exemplarically used to determine the optimum attachment point for a purine library targeting cyclin-dependent kinase 2 CDK2.

  1. New ENDF/B-7.0 library

    International Nuclear Information System (INIS)

    Oblozinsky, P.

    2008-01-01

    We describe the new version of the Evaluated Nuclear Data File, Endf/B-7.0, of recommended nuclear data for advanced nuclear science and technology applications. The library, produced by the US Cross Section Evaluation Working Group, was released in December 2006. The library contains data in 14 sub-libraries, primarily for reactions with incident neutrons, protons and photons, based on the experimental data and nuclear reaction theory predictions. The neutron reaction sub-library contains data for 393 materials. The new library was extensively tested and shows considerable improvements over the earlier Endf/B-6.8 library. (author)

  2. Multigroup cross section library; WIMS library

    International Nuclear Information System (INIS)

    Kannan, Umasankari

    2000-01-01

    The WIMS library has been extensively used in thermal reactor calculations. This multigroup constants library was originally developed from the UKNDL in the late 60's and has been updated in 1986. This library has been distributed with the WIMS-D code by NEA data bank. The references to WIMS library in literature are the 'old' which is the original as developed by the AEA Winfrith and the 'new' which is the current 1986 WIMS library. IAEA has organised a CRP where a new and fully updated WIMS library will soon be available. This paper gives an overview of the definitions of the group constants that go into any basic nuclear data library used for reactor calculations. This paper also outlines the contents of the WIMS library and some of its shortcomings

  3. ENEA-Bologna production and testing of Jeff-3.1 multi-group cross section libraries for nuclear fission applications

    International Nuclear Information System (INIS)

    Pescarini, M.; Orsi, R.; Sinitsa, V.

    2008-01-01

    The ENEA-Bologna Nuclear Data Group produced the JEFF-3.1 VITJEFF31.BOLIB and MATJEFF31. BOLIB fine-group coupled neutron and photon (199 n + 42 γ) cross section libraries for nuclear fission applications, respectively in AMPX and MATXS format, with the same specifications and energy group structure of the Endf/B-VI-3 VITAMIN-B6 American library. Each library, containing 181 nuclide cross section files, was generated from the same set of cross section data files in GENDF format, obtained through the Bondarenko (f-factor) method, with an ENEA-Bologna revised version of the GROUPR module of the NJOY-99.160 system. Collapsed working libraries of self-shielded cross sections in FIDO-ANISN format, used by the deterministic transport codes of the DANTSYS and DOORS systems, can be generated from VITJEFF31.BOLIB and MATJEFF31.BOLIB through, respectively, further data processing with an ENEA-Bologna revised version of the SCAMPI system and with the TRANSX code. This paper describes the methodology and specifications of the data processing performed and presents some results of the VITJEFF31.BOLIB validation. (authors)

  4. Development of the adjusted nuclear cross-section library based on JENDL-3.2 for large FBR

    International Nuclear Information System (INIS)

    Yokoyama, Kenji; Ishikawa, Makoto; Numata, Kazuyuki

    1999-04-01

    JNC (and PNC) had developed the adjusted nuclear cross-section library in which the results of the JUPITER experiments were reflected. Using this adjusted library, the distinct improvement of the accuracy in nuclear design of FBR cores had been achieved. As a recent research, JNC develops a database of other integral data in addition to the JUPITER experiments, aiming at further improvement for accuracy and reliability. In 1991, the adjusted library based on JENDL-2, JFS-3-J2 (ADJ91R), was developed, and it has been used on the design research for FBR. As an evaluated nuclear library, however, JENDL-3.2 is recently used. Therefore, the authors developed an adjusted library based on JENDL-3.2 which is called JFS-3-J3.2(ADJ98). It is known that the adjusted library based on JENDL-2 overestimated the sodium void reactivity worth by 10-20%. It is expected that the adjusted library based on JENDL-3.2 solve the problem. The adjusted library JFS-3-J3.2(ADJ98) was produced with the same method as the adjusted library JFS-3-J2(ADJ91R) and used more integral parameters of JUPITER experiments than the adjusted library JFS-3-J2(ADJ91R). This report also describes the design accuracy estimation on a 600 MWe class FBR with the adjusted library JFS-3-J3.2(ADJ98). Its main nuclear design parameters (multiplication factor, burn-up reactivity loss, breeding ratio, etc.) except the sodium void reactivity worth which are calculated with the adjusted library JFS-3-J3.2(ADJ98) are almost the same as those predicted with JFS-3-J2(ADJ91R). As for the sodium void reactivity, the adjusted library JFS-3-J3.2(ADJ98) estimates about 4% smaller than the JFS-3-J2(ADJ91R) because of the change of the basic nuclear library from JENDL-2 to JENDL-3.2. (author)

  5. Status of CINDER and ENDF/B-V based libraries for transmutation calculations

    International Nuclear Information System (INIS)

    Wilson, W.B.; England, T.R.; LaBauve, R.J.; Battat, M.E.; Wessol, D.E.; Perry, R.T.

    1980-01-01

    The CINDER codes and their data libraries are described, and their range of calculational capabilities are described using documented applications. The importance of ENDF/B data and the features of the ENDF/B-IV and ENDF/B-V fission-product and actinide data files are emphasized. The actinide decay data of ENDF/B-V, augmented by additional data from available sources, are used to produce average decay energy values and neutron source values from sponteneous fission, (α,n) and delayed neutron emission for 144 actinide nuclides that are formed in reactor fuel. The status and characteristics of the CINDER-2 code is described, along with a brief description of more well known code versions; a review of the status of new ENDF/B-V based libraries for all versions is presented

  6. A Generic High-performance GPU-based Library for PDE solvers

    DEFF Research Database (Denmark)

    Glimberg, Stefan Lemvig; Engsig-Karup, Allan Peter

    , the privilege of high-performance parallel computing is now in principle accessible for many scientific users, no matter their economic resources. Though being highly effective units, GPUs and parallel architectures in general, pose challenges for software developers to utilize their efficiency. Sequential...... legacy codes are not always easily parallelized and the time spent on conversion might not pay o in the end. We present a highly generic C++ library for fast assembling of partial differential equation (PDE) solvers, aiming at utilizing the computational resources of GPUs. The library requires a minimum...... of GPU computing knowledge, while still oering the possibility to customize user-specic solvers at kernel level if desired. Spatial dierential operators are based on matrix free exible order nite dierence approximations. These matrix free operators minimize both memory consumption and main memory access...

  7. Network Based Educational Environment How Libraries and Librarians Become Organizers of Knowledge Access and Resources

    CERN Document Server

    Pettenati, M C; Pettenati, Corrado

    2000-01-01

    In this paper we will highlight some important issues which will influence the redefinition of roles and duties of libraries and librarians in a networked based educational environment. Although librarians will also keep their traditional roles of faculty support services as well as reference service and research assistance, we identify the participation in the instructional design process, the support in the evaluation, development and use of a proper authoring system and the customization of information access, as being the domains where libraries and librarians should mainly involve themselves in the next future and make profit of their expertise in information and knowledge organization in order to properly and effectively support the institutions in the use of Information Technology in education.

  8. Specifications for adjusted cross section and covariance libraries based upon CSEWG fast reactor and dosimetry benchmarks

    International Nuclear Information System (INIS)

    Weisbin, C.R.; Marable, J.H.; Collins, P.J.; Cowan, C.L.; Peelle, R.W.; Salvatores, M.

    1979-06-01

    The present work proposes a specific plan of cross section library adjustment for fast reactor core physics analysis using information from fast reactor and dosimetry integral experiments and from differential data evaluations. This detailed exposition of the proposed approach is intended mainly to elicit review and criticism from scientists and engineers in the research, development, and design fields. This major attempt to develop useful adjusted libraries is based on the established benchmark integral data, accurate and well documented analysis techniques, sensitivities, and quantified uncertainties for nuclear data, integral experiment measurements, and calculational methodology. The adjustments to be obtained using these specifications are intended to produce an overall improvement in the least-squares sense in the quality of the data libraries, so that calculations of other similar systems using the adjusted data base with any credible method will produce results without much data-related bias. The adjustments obtained should provide specific recommendations to the data evaluation program to be weighed in the light of newer measurements, and also a vehicle for observing how the evaluation process is converging. This report specifies the calculational methodology to be used, the integral experiments to be employed initially, and the methods and integral experiment biases and uncertainties to be used. The sources of sensitivity coefficients, as well as the cross sections to be adjusted, are detailed. The formulae for sensitivity coefficients for fission spectral parameters are developed. A mathematical formulation of the least-square adjustment problem is given including biases and uncertainties in methods

  9. Development of library documents in BRICEM on network-based environment

    International Nuclear Information System (INIS)

    Gao Renxi

    2010-01-01

    With the development of the internet, the transformation from a traditional library to a modem one is essential to the development of BRICEM (Beijing Research Institute of Chemical Engineering and Metallurgy) Technology Library and the situations of other libraries, this thesis integrates the reality of BRICEM and its library in an effort to work out a tentative plan, as well as concrete measures and procedures of digitalising and online-sharing the resources of BRICEM Technology Library. (author)

  10. Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90.

    Science.gov (United States)

    Riccardi Sirtori, Federico; Caronni, Dannica; Colombo, Maristella; Dalvit, Claudio; Paolucci, Mauro; Regazzoni, Luca; Visco, Carlo; Fogliatto, Gianpaolo

    2015-08-30

    ESI-MS is a well established technique for the study of biopolymers (nucleic acids, proteins) and their non covalent adducts, due to its capacity to detect ligand-target complexes in the gas phase and allows inference of ligand-target binding in solution. In this article we used this approach to investigate the interaction of ligands to the Heat Shock Protein 90 (Hsp90). This enzyme is a molecular chaperone involved in the folding and maturation of several proteins which has been subjected in the last years to intensive drug discovery efforts due to its key role in cancer. In particular, reference compounds, with a broad range of dissociation constants from 40pM to 100μM, were tested to assess the reliability of ESI-MS for the study of protein-ligand complexes. A good agreement was found between the values measured with a fluorescence polarization displacement assay and those determined by mass spectrometry. After this validation step we describe the setup of a medium throughput screening method, based on ESI-MS, suitable to explore interactions of therapeutic relevance biopolymers with chemical libraries. Our approach is based on an automated flow injection ESI-MS method (AFI-MS) and has been applied to screen the Nerviano Medical Sciences proprietary fragment library of about 2000 fragments against Hsp90. In order to discard false positive hits and to discriminate those of them interacting with the N-terminal ATP binding site, competition experiments were performed using a reference inhibitor. Gratifyingly, this group of hits matches with the ligands previously identified by NMR FAXS techniques and confirmed by X-ray co-crystallization experiments. These results support the use of AFI-MS for the screening of medium size libraries, including libraries of small molecules with low affinity typically used in fragment based drug discovery. AFI-MS is a valid alternative to other techniques with the additional opportunities to identify compounds interacting with

  11. 工作設計對大學圖書館團體認同之影響 Improving Group Identity by Job Design in Academic Libraries

    Directory of Open Access Journals (Sweden)

    In-Lin Hu

    2009-12-01

    Full Text Available 團體認同度影響大學圖書館工作人員知識分享的意圖和品質,目前,從館員職務設計和工作任務特點的角度,探討團體認同度和圖書館內部知識共享之影響的相關研究尚不多。本研究發現團體認同度對於改善大學圖書館的知識共享意圖和品質有其重要的影響,而職務設計和工作任務的適當與否,亦影響館員的團體認同度。Group identity in academic library determinants the intention of knowledge sharing and knowledge quality. However, the investigation of job design and task characteristics influences group identity and internal library knowledge sharing is still very rudimentary. The study indicated that group identity is important in improving knowledge sharing intentions in academic libraries. Group identity is associated with different kinds of task characteristics. Both organizational prestige and task characteristics are able to explain significant amounts of variance of group identity.

  12. Open source libraries and frameworks for mass spectrometry based proteomics: A developer's perspective☆

    Science.gov (United States)

    Perez-Riverol, Yasset; Wang, Rui; Hermjakob, Henning; Müller, Markus; Vesada, Vladimir; Vizcaíno, Juan Antonio

    2014-01-01

    Data processing, management and visualization are central and critical components of a state of the art high-throughput mass spectrometry (MS)-based proteomics experiment, and are often some of the most time-consuming steps, especially for labs without much bioinformatics support. The growing interest in the field of proteomics has triggered an increase in the development of new software libraries, including freely available and open-source software. From database search analysis to post-processing of the identification results, even though the objectives of these libraries and packages can vary significantly, they usually share a number of features. Common use cases include the handling of protein and peptide sequences, the parsing of results from various proteomics search engines output files, and the visualization of MS-related information (including mass spectra and chromatograms). In this review, we provide an overview of the existing software libraries, open-source frameworks and also, we give information on some of the freely available applications which make use of them. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. PMID:23467006

  13. EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries.

    Science.gov (United States)

    Smith, Robin P; Buchser, William J; Lemmon, Marcus B; Pardinas, Jose R; Bixby, John L; Lemmon, Vance P

    2008-04-10

    Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as UniGene and centralized annotation engines such as Entrez Gene has allowed the development of software that can analyze a great number of sequences in a matter of seconds. We have developed "EST Express", a suite of analytical tools that identify and annotate ESTs originating from specific mRNA populations. The software consists of a user-friendly GUI powered by PHP and MySQL that allows for online collaboration between researchers and continuity with UniGene, Entrez Gene and RefSeq. Two key features of the software include a novel, simplified Entrez Gene parser and tools to manage cDNA library sequencing projects. We have tested the software on a large data set (2,016 samples) produced by subtractive hybridization. EST Express is an open-source, cross-platform web server application that imports sequences from cDNA libraries, such as those generated through subtractive hybridization or yeast two-hybrid screens. It then provides several layers of annotation based on Entrez Gene and RefSeq to allow the user to highlight useful genes and manage cDNA library projects.

  14. EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries

    Directory of Open Access Journals (Sweden)

    Pardinas Jose R

    2008-04-01

    Full Text Available Abstract Background Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as UniGene and centralized annotation engines such as Entrez Gene has allowed the development of software that can analyze a great number of sequences in a matter of seconds. Results We have developed "EST Express", a suite of analytical tools that identify and annotate ESTs originating from specific mRNA populations. The software consists of a user-friendly GUI powered by PHP and MySQL that allows for online collaboration between researchers and continuity with UniGene, Entrez Gene and RefSeq. Two key features of the software include a novel, simplified Entrez Gene parser and tools to manage cDNA library sequencing projects. We have tested the software on a large data set (2,016 samples produced by subtractive hybridization. Conclusion EST Express is an open-source, cross-platform web server application that imports sequences from cDNA libraries, such as those generated through subtractive hybridization or yeast two-hybrid screens. It then provides several layers of annotation based on Entrez Gene and RefSeq to allow the user to highlight useful genes and manage cDNA library projects.

  15. Open source libraries and frameworks for mass spectrometry based proteomics: a developer's perspective.

    Science.gov (United States)

    Perez-Riverol, Yasset; Wang, Rui; Hermjakob, Henning; Müller, Markus; Vesada, Vladimir; Vizcaíno, Juan Antonio

    2014-01-01

    Data processing, management and visualization are central and critical components of a state of the art high-throughput mass spectrometry (MS)-based proteomics experiment, and are often some of the most time-consuming steps, especially for labs without much bioinformatics support. The growing interest in the field of proteomics has triggered an increase in the development of new software libraries, including freely available and open-source software. From database search analysis to post-processing of the identification results, even though the objectives of these libraries and packages can vary significantly, they usually share a number of features. Common use cases include the handling of protein and peptide sequences, the parsing of results from various proteomics search engines output files, and the visualization of MS-related information (including mass spectra and chromatograms). In this review, we provide an overview of the existing software libraries, open-source frameworks and also, we give information on some of the freely available applications which make use of them. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Key Performance Indicators in Irish Hospital Libraries: Developing Outcome-Based Metrics

    Directory of Open Access Journals (Sweden)

    Michelle Dalton

    2012-12-01

    Full Text Available Objective – To develop a set of generic outcome-based performance measures for Irishhospital libraries.Methods – Various models and frameworks of performance measurement were used as atheoretical paradigm to link the impact of library services directly with measurablehealthcare objectives and outcomes. Strategic objectives were identified, mapped toperformance indicators, and finally translated into response choices to a single-questiononline survey for distribution via email.Results – The set of performance indicators represents an impact assessment tool whichis easy to administer across a variety of healthcare settings. In using a model directlyaligned with the mission and goals of the organization, and linked to core activities andoperations in an accountable way, the indicators can also be used as a channel throughwhich to implement action, change, and improvement.Conclusion – The indicators can be adopted at a local and potentially a national level, asboth a tool for advocacy and to assess and improve service delivery at a macro level. Toovercome the constraints posed by necessary simplifications, substantial further research is needed by hospital libraries to develop more sophisticated and meaningful measures of impact to further aid decision making at a micro level.

  17. Validation of the BUGJEFF311.BOLIB, BUGENDF70.BOLIB and BUGLE-B7 broad-group libraries on the PCA-Replica (H2O/Fe) neutron shielding benchmark experiment

    OpenAIRE

    Pescarini Massimo; Orsi Roberto; Frisoni Manuela

    2016-01-01

    The PCA-Replica 12/13 (H2O/Fe) neutron shielding benchmark experiment was analysed using the TORT-3.2 3D SN code. PCA-Replica reproduces a PWR ex-core radial geometry with alternate layers of water and steel including a pressure vessel simulator. Three broad-group coupled neutron/photon working cross section libraries in FIDO-ANISN format with the same energy group structure (47 n + 20 γ) and based on different nuclear data were alternatively used: the ENEA BUGJEFF311.BOLIB (JEFF-3.1.1) and U...

  18. Target based screening of small molecule library identifies pregnelonene, a Nrf2 agonist, as a potential radioprotector in zebrafish

    International Nuclear Information System (INIS)

    Joshi, Jayadev; Ghosh, Subhajit; Dimri, Manali; Shrivastava, Nitisha; Indracanti, Prem Kumar; Ray, Jharna

    2014-01-01

    Reactive oxygen species, cellular oxidative stress, tissue inflammation and cell death are the downstream consequences of radiation exposures which ultimately could lead to organism death. Present study aims at identifying potential targets and screening of small molecule compound library for identifying novel and effective radioprotectors. In-silco analysis of known radioprotectors revealed three main function, antioxidant, anti-inflammation and antiapoptosis. In this study, a collection of small molecules (John Hopkins Clinical Compound Library, JHCCL) were screened for these different functions using the biological activity database of NCBI with the help of in-house developed python script. Further, filtering of the JHCCL was done by searching for molecules which are known to be active against target of radiobiological significance, Nrf-2. Close observation of potential hits identified, pregnenolone, as an Nrf-2 agonist which was further evaluated for radioprotection in zebrafish model. Pregnenolone rendered significant protection (at 40 μM; added 1 hour prior to 20 Gy gamma radiation) in terms of damage manifestations (pericardial edema, microcephaly, micropthalmia, yolk sac resorption, curvature of spine, blood flow, body length, heart-beat, blood clot, roughness of skin) and survival advantage (60%) when compared to irradiated control. Further, the ability of pregnenolone to act as a neuroprotectant was also carried out using in-house developed software for assessing neuromotor functions. In comparison to radiation alone group, pregnenolone was found to possess significant neuroactive functions and diminished radiation induced neuronal impairment. Over all these results suggests that pregnenolone is an effective radioprotector which warrants further investigation for validation of its radioprotective action in higher vertebrates. Apart from that the utility of approach to screen out bioactivity data base of various chemical compound libraries for possible

  19. Research evaluation support services in biomedical libraries.

    Science.gov (United States)

    Gutzman, Karen Elizabeth; Bales, Michael E; Belter, Christopher W; Chambers, Thane; Chan, Liza; Holmes, Kristi L; Lu, Ya-Ling; Palmer, Lisa A; Reznik-Zellen, Rebecca C; Sarli, Cathy C; Suiter, Amy M; Wheeler, Terrie R

    2018-01-01

    The paper provides a review of current practices related to evaluation support services reported by seven biomedical and research libraries. A group of seven libraries from the United States and Canada described their experiences with establishing evaluation support services at their libraries. A questionnaire was distributed among the libraries to elicit information as to program development, service and staffing models, campus partnerships, training, products such as tools and reports, and resources used for evaluation support services. The libraries also reported interesting projects, lessons learned, and future plans. The seven libraries profiled in this paper report a variety of service models in providing evaluation support services to meet the needs of campus stakeholders. The service models range from research center cores, partnerships with research groups, and library programs with staff dedicated to evaluation support services. A variety of products and services were described such as an automated tool to develop rank-based metrics, consultation on appropriate metrics to use for evaluation, customized publication and citation reports, resource guides, classes and training, and others. Implementing these services has allowed the libraries to expand their roles on campus and to contribute more directly to the research missions of their institutions. Libraries can leverage a variety of evaluation support services as an opportunity to successfully meet an array of challenges confronting the biomedical research community, including robust efforts to report and demonstrate tangible and meaningful outcomes of biomedical research and clinical care. These services represent a transformative direction that can be emulated by other biomedical and research libraries.

  20. An Emerging Theory for Evidence Based Information Literacy Instruction in School Libraries, Part 2: Building a Culture of Inquiry

    Directory of Open Access Journals (Sweden)

    Carol A. Gordon

    2009-09-01

    Full Text Available Objective – The purpose of this paper is to articulate a theory for the use of action research as a tool of evidence based practice for information literacy instruction in school libraries. The emerging theory is intended to capture the complex phenomenon of information skills teaching as it is embedded in school curricula. Such a theory is needed to support research on the integrated approach to teaching information skills and knowledge construction within the framework of inquiry learning. Part 1 of this paper, in the previous issue, built a foundation for emerging theory, which established user‐centric information behavior and constructivist learning theory as the substantive theory behind evidence based library instruction in schools. Part 2 continues to build on the Information Search Process and Guided Inquiry as foundational to studying the information‐to‐knowledge connection and the concepts of help and intervention characteristic of 21st century school library instruction.Methods – This paper examines the purpose and methodology of action research as a tool of evidence based instruction. This is accomplished through the explication of three components of theory‐building: paradigm, substantive research, and metatheory. Evidence based practice is identified as the paradigm that contributes values and assumptions about school library instruction. It establishes the role of evidence in teaching and learning, linking theory and practice. Action research, as a tool of evidence based practice is defined as the synthesis of authentic learning, or performance‐based assessment practices that continuously generate evidence throughout the inquiry unit of instruction and traditional data collection methods typically used in formal research. This paper adds social psychology theory from Lewin’s work, which contributes methodology from Gestalt psychology, field theory, group dynamics, and change theory. For Lewin the purpose of action

  1. Featured Library: Parrish Library

    OpenAIRE

    Kirkwood, Hal P, Jr

    2015-01-01

    The Roland G. Parrish Library of Management & Economics is located within the Krannert School of Management at Purdue University. Between 2005 - 2007 work was completed on a white paper that focused on a student-centered vision for the Management & Economics Library. The next step was a massive collection reduction and a re-envisioning of both the services and space of the library. Thus began a 3 phase renovation from a 2 floor standard, collection-focused library into a single floor, 18,000s...

  2. Are the Deaf a Disabled Group, or a Linguistic Minority? Issues for Librarians in Victoria's Public Libraries

    Science.gov (United States)

    McQuigg, Karen

    2003-01-01

    Presents a brief overview of the sociological forces shaping the discourse of disability; examines the part that public libraries have played, or failed to play, in addressing issues of exclusion as they relate to people with disabilities. Focuses on Australia's deaf community and its particular informational needs. The low impact of the…

  3. An Evidence Based Methodology to Facilitate Public Library Non-fiction Collection Development

    Directory of Open Access Journals (Sweden)

    Matthew Kelly

    2015-12-01

    Full Text Available Objective – This research was designed as a pilot study to test a methodology for subject based collection analysis for public libraries. Methods – WorldCat collection data from eight Australian public libraries was extracted using the Collection Evaluation application. The data was aggregated and filtered to assess how the sample’s titles could be compared against the OCLC Conspectus subject categories. A hierarchy of emphasis emerged and this was divided into tiers ranging from 1% of the sample. These tiers were further analysed to quantify their representativeness against both the sample’s titles and the subject categories taken as a whole. The interpretive aspect of the study sought to understand the types of knowledge embedded in the tiers and was underpinned by hermeneutic phenomenology. Results – The study revealed that there was a marked tendency for a small percentage of subject categories to constitute a large proportion of the potential topicality that might have been represented in these types of collections. The study also found that distribution of the aggregated collection conformed to a Power Law distribution (80/20 so that approximately 80% of the collection was represented by 20% of the subject categories. The study also found that there were significant commonalities in the types of subject categories that were found in the designated tiers and that it may be possible to develop ontologies that correspond to the collection tiers. Conclusions – The evidence-based methodology developed in this pilot study has the potential for further development to help to improve the practice of collection development. The introduction of the concept of the epistemic role played by collection tiers is a promising aid to inform our understanding of knowledge organization for public libraries. The research shows a way forward to help to link subjective decision making with a scientifically based approach to managing knowledge

  4. Libraries serving dialogue

    CERN Document Server

    Dupont, Odile

    2014-01-01

    This book based on experiences of libraries serving interreligious dialogue, presents themes like library tools serving dialogue between cultures, collections dialoguing, children and young adults dialoguing beyond borders, story telling as dialog, librarians serving interreligious dialogue.

  5. New Neutron, Proton, and S(α,β) MCNP Data Libraries Based on ENDF/B-VII

    International Nuclear Information System (INIS)

    Little, Robert C.; Trellue, Holly R.; MacFarlane, Robert E.; Kahler, A.C.; Lee, Mary Beth; White, Morgan C.

    2008-01-01

    The general-purpose Evaluated Nuclear Data File ENDF/B-VII.0 was released in December 2006. A number of sub-libraries were included in ENDF/B-VII.0 such that data were provided for incident neutrons, photons, and charged particles. This paper describes the creation of MCNP data libraries at Los Alamos National Laboratory based on three ENDF/B-VII.0 sub-libraries: neutrons, protons, and thermal scattering. An ACE-formatted continuous-energy neutron data library called ENDF70 for MCNP has been produced. This library provides data for 390 materials at five temperatures: 293.6, 600, 900, 1200, and 2500 K. The library was processed primarily with Version 248 of NJOY99. Extensive checking and quality-assurance tests were applied to the data. Improvements to the processing code were made and certain evaluations were modified as a result of these tests. ENDF/B-VII.0 included proton evaluations for 48 target materials. Forty-seven proton evaluations (all except for 13 C) were processed at room temperature and combined into the MCNP library ENDF70PROT. Neutron thermal S(α,β) scattering data exist for twenty different materials in ENDF/B-VII.0. All twenty of these evaluations were processed at all applicable temperatures (these vary for each evaluation), and combined into the MCNP library ENDF70SAB. All of these ENDF/B-VII.0 based MCNP libraries (ENDF70, ENDF70PROT, and ENDF70SAB) are available as part of the MCNP5 1.50 release. (authors)

  6. Discovery of potent inhibitors of soluble epoxide hydrolase by combinatorial library design and structure-based virtual screening.

    Science.gov (United States)

    Xing, Li; McDonald, Joseph J; Kolodziej, Steve A; Kurumbail, Ravi G; Williams, Jennifer M; Warren, Chad J; O'Neal, Janet M; Skepner, Jill E; Roberds, Steven L

    2011-03-10

    Structure-based virtual screening was applied to design combinatorial libraries to discover novel and potent soluble epoxide hydrolase (sEH) inhibitors. X-ray crystal structures revealed unique interactions for a benzoxazole template in addition to the conserved hydrogen bonds with the catalytic machinery of sEH. By exploitation of the favorable binding elements, two iterations of library design based on amide coupling were employed, guided principally by the docking results of the enumerated virtual products. Biological screening of the libraries demonstrated as high as 90% hit rate, of which over two dozen compounds were single digit nanomolar sEH inhibitors by IC(50) determination. In total the library design and synthesis produced more than 300 submicromolar sEH inhibitors. In cellular systems consistent activities were demonstrated with biochemical measurements. The SAR understanding of the benzoxazole template provides valuable insights into discovery of novel sEH inhibitors as therapeutic agents.

  7. Promoter library-based module combination (PLMC) technology for optimization of threonine biosynthesis in Corynebacterium glutamicum.

    Science.gov (United States)

    Wei, Liang; Xu, Ning; Wang, Yiran; Zhou, Wei; Han, Guoqiang; Ma, Yanhe; Liu, Jun

    2018-05-01

    Due to the lack of efficient control elements and tools, the fine-tuning of gene expression in the multi-gene metabolic pathways is still a great challenge for engineering microbial cell factories, especially for the important industrial microorganism Corynebacterium glutamicum. In this study, the promoter library-based module combination (PLMC) technology was developed to efficiently optimize the expression of genes in C. glutamicum. A random promoter library was designed to contain the putative - 10 (NNTANANT) and - 35 (NNGNCN) consensus motifs, and refined through a three-step screening procedure to achieve numerous genetic control elements with different strength levels, including fluorescence-activated cell sorting (FACS) screening, agar plate screening, and 96-well plate screening. Multiple conventional strategies were employed for further precise characterizations of the promoter library, such as real-time quantitative PCR, sodium dodecyl sulfate polyacrylamide gel electrophoresis, FACS analysis, and the lacZ reporter system. These results suggested that the established promoter elements effectively regulated gene expression and showed varying strengths over a wide range. Subsequently, a multi-module combination technology was created based on the efficient promoter elements for combination and optimization of modules in the multi-gene pathways. Using this technology, the threonine biosynthesis pathway was reconstructed and optimized by predictable tuning expression of five modules in C. glutamicum. The threonine titer of the optimized strain was significantly improved to 12.8 g/L, an approximate 6.1-fold higher than that of the control strain. Overall, the PLMC technology presented in this study provides a rapid and effective method for combination and optimization of multi-gene pathways in C. glutamicum.

  8. A graph-based approach to construct target-focused libraries for virtual screening.

    Science.gov (United States)

    Naderi, Misagh; Alvin, Chris; Ding, Yun; Mukhopadhyay, Supratik; Brylinski, Michal

    2016-01-01

    Due to exorbitant costs of high-throughput screening, many drug discovery projects commonly employ inexpensive virtual screening to support experimental efforts. However, the vast majority of compounds in widely used screening libraries, such as the ZINC database, will have a very low probability to exhibit the desired bioactivity for a given protein. Although combinatorial chemistry methods can be used to augment existing compound libraries with novel drug-like compounds, the broad chemical space is often too large to be explored. Consequently, the trend in library design has shifted to produce screening collections specifically tailored to modulate the function of a particular target or a protein family. Assuming that organic compounds are composed of sets of rigid fragments connected by flexible linkers, a molecule can be decomposed into its building blocks tracking their atomic connectivity. On this account, we developed eSynth, an exhaustive graph-based search algorithm to computationally synthesize new compounds by reconnecting these building blocks following their connectivity patterns. We conducted a series of benchmarking calculations against the Directory of Useful Decoys, Enhanced database. First, in a self-benchmarking test, the correctness of the algorithm is validated with the objective to recover a molecule from its building blocks. Encouragingly, eSynth can efficiently rebuild more than 80 % of active molecules from their fragment components. Next, the capability to discover novel scaffolds is assessed in a cross-benchmarking test, where eSynth successfully reconstructed 40 % of the target molecules using fragments extracted from chemically distinct compounds. Despite an enormous chemical space to be explored, eSynth is computationally efficient; half of the molecules are rebuilt in less than a second, whereas 90 % take only about a minute to be generated. eSynth can successfully reconstruct chemically feasible molecules from molecular fragments

  9. OpenCL-Based Linear Algebra Libraries for High-Performance Computing, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Despite its promise, OpenCL adoption is slow, owing to a lack of libraries and tools. Vendors have shown few signs of plans to provide OpenCL libraries, and were...

  10. Validation of the BUGJEFF311.BOLIB, BUGENDF70.BOLIB and BUGLE-B7 broad-group libraries on the PCA-Replica (H2O/Fe neutron shielding benchmark experiment

    Directory of Open Access Journals (Sweden)

    Pescarini Massimo

    2016-01-01

    Full Text Available The PCA-Replica 12/13 (H2O/Fe neutron shielding benchmark experiment was analysed using the TORT-3.2 3D SN code. PCA-Replica reproduces a PWR ex-core radial geometry with alternate layers of water and steel including a pressure vessel simulator. Three broad-group coupled neutron/photon working cross section libraries in FIDO-ANISN format with the same energy group structure (47 n + 20 γ and based on different nuclear data were alternatively used: the ENEA BUGJEFF311.BOLIB (JEFF-3.1.1 and UGENDF70.BOLIB (ENDF/B-VII.0 libraries and the ORNL BUGLE-B7 (ENDF/B-VII.0 library. Dosimeter cross sections derived from the IAEA IRDF-2002 dosimetry file were employed. The calculated reaction rates for the Rh-103(n,n′Rh-103m, In-115(n,n′In-115m and S-32(n,pP-32 threshold activation dosimeters and the calculated neutron spectra are compared with the corresponding experimental results.

  11. Validation of the BUGJEFF311.BOLIB, BUGENDF70.BOLIB and BUGLE-B7 broad-group libraries on the PCA-Replica (H2O/Fe) neutron shielding benchmark experiment

    Science.gov (United States)

    Pescarini, Massimo; Orsi, Roberto; Frisoni, Manuela

    2016-03-01

    The PCA-Replica 12/13 (H2O/Fe) neutron shielding benchmark experiment was analysed using the TORT-3.2 3D SN code. PCA-Replica reproduces a PWR ex-core radial geometry with alternate layers of water and steel including a pressure vessel simulator. Three broad-group coupled neutron/photon working cross section libraries in FIDO-ANISN format with the same energy group structure (47 n + 20 γ) and based on different nuclear data were alternatively used: the ENEA BUGJEFF311.BOLIB (JEFF-3.1.1) and UGENDF70.BOLIB (ENDF/B-VII.0) libraries and the ORNL BUGLE-B7 (ENDF/B-VII.0) library. Dosimeter cross sections derived from the IAEA IRDF-2002 dosimetry file were employed. The calculated reaction rates for the Rh-103(n,n')Rh-103m, In-115(n,n')In-115m and S-32(n,p)P-32 threshold activation dosimeters and the calculated neutron spectra are compared with the corresponding experimental results.

  12. Circulation policies in health science libraries.

    Science.gov (United States)

    Watkins, C; Coker, N C

    1970-10-01

    There is general agreement that library policies have considerable influence on the use of libraries. Medical school (health science) libraries of this country were surveyed as to their policies in respect to whether faculty and student use were regulated by a single policy, circulation regulations, hours library was accessible to users, accessibility of reserve material, interlibrary loan, policy on overdue material, and exit control. THE LIBRARIES WERE THEN DIVIDED INTO THREE GROUPS, HIGH, MIDDLE, AND LOW ACCORDING TO THE FOLLOWING CHARACTERISTICS: size of student body, size of faculty, size of holdings, size of library staff, annual budget, and annual circulation. Our findings would indicate that schools falling in a high category based upon these criteria tend to be more restrictive in their policies and to have different regulations for faculty and students than do schools in the low category.These findings warrant further study.

  13. Getting to Know Library Users' Needs

    DEFF Research Database (Denmark)

    Harbo, Karen; Hansen, Thomas Erlandson V.

    2012-01-01

    'Meeting the User' is a programme committee under the Danish Electronic Research Library. As a development group at a national level we see our role as facilitating an innovative culture within academic libraries, focusing on users' needs and the way libraries meet them. In collaboration...... a description of the above-mentioned methods, valuable experiences from the workshop, a presentation of the concept and concrete tools, discussion of the concept of user logic and library services, and the seven principles for human-centered innovation in relation to libraries, a short list of studies carried...... with a consultancy firm, the commitee organized a travelling workshop in four cities in 2010. The workshop introduced practical ways for library staff to get to know their users' needs for services and was based on anthropological methods. The travelling workshop was part of a larger project called 'A Journey...

  14. Generating resources for genomics of wheat homoeologous chromosome group 3: 3AS- and 3DS-specific BAC libraries

    Czech Academy of Sciences Publication Activity Database

    Šafář, Jan; Šimková, Hana; Kubaláková, Marie; Suchánková, Pavla; Čihalíková, Jarmila; Bartoš, Jan; Fiocchetti, F.; Roselli, M.; Gill, B. S.; Doležel, Jaroslav; Lucretti, S.

    2009-01-01

    Roč. 61, 1-2 (2009), s. 151-160 ISSN 0394-9257 R&D Projects: GA ČR GD521/05/H013; GA ČR GA521/06/1723; GA ČR GA521/07/1573; GA MŠk(CZ) LC06004; GA MŠk OC08025 Institutional research plan: CEZ:AV0Z50380511 Keywords : BAC library * Flow sorting * Homoeologous chromosomes Subject RIV: GE - Plant Breeding

  15. Potentials of fee-based library services in Nigeria: with a case report ...

    African Journals Online (AJOL)

    Libraries have traditionally been custodians of information which are provided free of charge to users. Recent decline in funds to libraries and the change in the concept of information from a free resource to a marketable resource in the information age have necessitated the re-evaluation of free services in the libraries.

  16. Structure-based virtual screening of molecular libraries as cdk2 inhibitors

    International Nuclear Information System (INIS)

    Riaz, U.; Khaleeq, M.

    2011-01-01

    CDK2 inhibitor is an important target in multiple processes associated with tumor growth and development, including proliferation, neovascularization, and metastasis. In this study, hit identification was performed by virtual screening of commercial and in-house compound libraries. Docking studies for the hits were performed, and scoring functions were used to evaluate the docking results and to rank ligand-binding affinities. Subsequently, hit optimization for potent and selective candidate CDK2 inhibitors was performed through focused library design and docking analyses. Consequently, we report that a novel compound with an IC50 value of 89 nM, representing 2-Amino-4,6-di-(4',6'-dibromophenyl)pyrimidine 1, is highly selective for CDK2 inhibitors. The docking structure of compound 1 with CDK2 inhibitor disclosed that the NH moiety and pyrimidine ring appeared to fit tightly into the hydrophobic pocket of CDK2 inhibitor. Additionally, the pyrimidine NH forms a hydrogen bond with the carboxyl group of Asp348. These results confirm the successful application of virtual screening studies in the lead discovery process, and suggest that our novel compound can be an effective CDK2 inhibitor candidate for further lead optimization. (author)

  17. Group-ID based RFID Mutual Authentication

    Directory of Open Access Journals (Sweden)

    LEE, Y.

    2013-11-01

    Full Text Available For passive type RFID tags, EPCglobal Class 1 Generation-2 Revision is used widely as a de facto standard. As it was designed for low cost, it is quite vulnerable to security issues, such as privacy concerns. This paper presents a new RFID mutual authentication protocol, which is designed to be configured on EPC Gen2 platform and to meet various security requirements while providing efficiency using PRNG (Pseudo Random Number Generator. Group-ID is used to minimize the authentication time. Security analysis of the proposed protocol is discussed.

  18. Creating a web-based digital photographic archive: one hospital library's experience.

    Science.gov (United States)

    Marshall, Caroline; Hobbs, Janet

    2017-04-01

    Cedars-Sinai Medical Center is a nonprofit community hospital based in Los Angeles. Its history spans over 100 years, and its growth and development from the merging of 2 Jewish hospitals, Mount Sinai and Cedars of Lebanon, is also part of the history of Los Angeles. The medical library collects and maintains the hospital's photographic archive, to which retiring physicians, nurses, and an active Community Relations Department have donated photographs over the years. The collection was growing rapidly, it was impossible to display all the materials, and much of the collection was inaccessible to patrons. The authors decided to make the photographic collection more accessible to medical staff and researchers by purchasing a web-based digital archival package, Omeka. We decided what material should be digitized by analyzing archival reference requests and considering the institution's plan to create a Timeline Wall documenting and celebrating the history of Cedars-Sinai. Within 8 months, we digitized and indexed over 500 photographs. The digital archive now allows patrons and researchers to access the history of the hospital and enables the library to process archival references more efficiently.

  19. phpMs: A PHP-Based Mass Spectrometry Utilities Library.

    Science.gov (United States)

    Collins, Andrew; Jones, Andrew R

    2018-03-02

    The recent establishment of cloud computing, high-throughput networking, and more versatile web standards and browsers has led to a renewed interest in web-based applications. While traditionally big data has been the domain of optimized desktop and server applications, it is now possible to store vast amounts of data and perform the necessary calculations offsite in cloud storage and computing providers, with the results visualized in a high-quality cross-platform interface via a web browser. There are number of emerging platforms for cloud-based mass spectrometry data analysis; however, there is limited pre-existing code accessible to web developers, especially for those that are constrained to a shared hosting environment where Java and C applications are often forbidden from use by the hosting provider. To remedy this, we provide an open-source mass spectrometry library for one of the most commonly used web development languages, PHP. Our new library, phpMs, provides objects for storing and manipulating spectra and identification data as well as utilities for file reading, file writing, calculations, peptide fragmentation, and protein digestion as well as a software interface for controlling search engines. We provide a working demonstration of some of the capabilities at http://pgb.liv.ac.uk/phpMs .

  20. McMaster PLUS: a cluster randomized clinical trial of an intervention to accelerate clinical use of evidence-based information from digital libraries.

    Science.gov (United States)

    Haynes, R Brian; Holland, Jennifer; Cotoi, Chris; McKinlay, R James; Wilczynski, Nancy L; Walters, Leslie A; Jedras, Dawn; Parrish, Rick; McKibbon, K Ann; Garg, Amit; Walter, Stephen D

    2006-01-01

    Physicians have difficulty keeping up with new evidence from medical research. We developed the McMaster Premium LiteratUre Service (PLUS), an internet-based addition to an existing digital library, which delivered quality- and relevance-rated medical literature to physicians, matched to their clinical disciplines. We evaluated PLUS in a cluster-randomized trial of 203 participating physicians in Northern Ontario, comparing a Full-Serve version (that included alerts to new articles and a cumulative database of alerts) with a Self-Serve version (that included a passive guide to evidence-based literature). Utilization of the service was the primary trial end-point. Mean logins to the library rose by 0.77 logins/month/user (95% CI 0.43, 1.11) in the Full-Serve group compared with the Self-Serve group. The proportion of Full-Serve participants who utilized the service during each month of the study period showed a sustained increase during the intervention period, with a relative increase of 57% (95% CI 12, 123) compared with the Self-Serve group. There were no differences in these proportions during the baseline period, and following the crossover of the Self-Serve group to Full-Serve, the Self-Serve group's usage became indistinguishable from that of the Full-Serve group (relative difference 4.4 (95% CI -23.7, 43.0). Also during the intervention and crossover periods, measures of self-reported usefulness did not show a difference between the 2 groups. A quality- and relevance-rated online literature service increased the utilization of evidence-based information from a digital library by practicing physicians.

  1. EJ2-MCNPlib. Contents of the JEF-2.2 based neutron cross-section library for MCNP4A

    International Nuclear Information System (INIS)

    Hogenbirk, A.; Oppe, J.

    1995-05-01

    In this report a description is given of the EJ2-MCNPlib library. The EJ2-MCNPlib library is to be used for reactivity/critically calculations and general neutron/photon transport calculations with the Monte Carlo code MCNP4A. The library is based on the European JEF-2.2 nuclear data evaluation and contains data for all (i.e. 313) nuclides available on this evaluation.The cross-section data were generated using the NJOY cross-section processing code system, version 91.118. For easy reference cross-section plots are given in this report for the total, elastic and absorption cross sections for all nuclides on the EJ2-MCNPlib library. Furthermore, for verification purposes a graphical intercomparison is given of the results of standard benchmark calculations performed with JEF-2.2 cross-section data and with ENDF/B-V cross-section data (whenever available). 6 refs

  2. Measuring patrons' technology habits: an evidence-based approach to tailoring library services.

    Science.gov (United States)

    Wu, Jin; Chatfield, Amy J; Hughes, Annie M; Kysh, Lynn; Rosenbloom, Megan Curran

    2014-04-01

    Librarians continually integrate new technologies into library services for health sciences students. Recently published data are lacking about student ownership of technological devices, awareness of new technologies, and interest in using devices and technologies to interact with the library. A survey was implemented at seven health sciences libraries to help answer these questions. Results show that librarian assumptions about awareness of technologies are not supported, and student interest in using new technologies to interact with the library varies widely. Collecting this evidence provides useful information for successfully integrating technologies into library services.

  3. Calculation and analysis of the source term of the reactor core based on different data libraries

    International Nuclear Information System (INIS)

    Chen Haiying; Zhang Chunming; Wang Shaowei; Lan Bing; Liu Qiaofeng; Han Jingru

    2014-01-01

    The nuclear fuel in reactor core produces large amount of radioactive nuclides in the fission process. ORIGEN-S can calculate the accumulation and decay of radioactive nuclides in the core by using various forms of data libraries, including card-image library, binary library and ORIGEN-S cross section library generated by ARP through interpolation method. In this paper, the information of each data library was described, and the reactor core inventory was calculated by using Card-image library and ARP library. The radioactivity concentration of typical nuclides with the change of fuel burnup was analyzed. The results showed that the influence of data libraries on the calculation of nuclide radioactivity was various. Compared to Card-image library, the radioactivity of a small part of nuclides calculated by ARP library were larger and the radioactivity of "1"3"4Cs, "1"3"6Cs were calculated smaller by about 15%. For some typical nuclides, with the deepening of fuel burnup, the difference of nuclide radioactivity calculated by the two libraries increased. However, the changes of the ratio of nuclide radioactivity were different. (authors)

  4. Implementation of Hierarchical Authorization For A Web-Based Digital Library

    Directory of Open Access Journals (Sweden)

    Andreas Geyer-Schulz

    2007-04-01

    Full Text Available Access control mechanisms are needed in almost every system nowadays to control what kind of access each user has to which resources and when. On the one hand access control systems need to be flexible to allow the definition of the access rules that are actually needed. But they must also be easy to administrate to prevent rules from being in place without the administrator realizing it. This is particularly difficult for systems such as a digital library that requires fine-grained access rules specifying access control at a document level. We present the implementation and architecture of a system that allows definition of access rights down to the single document and user level. We use hierarchies on users and roles, hierachies on access rights and hierarchies on documents and document groups. These hierarchies allow a maximum of flexibility and still keep the system easy enough to administrate. Our access control system supports positive as well as negative permissions.

  5. Changing State Digital Libraries

    Science.gov (United States)

    Pappas, Marjorie L.

    2006-01-01

    Research has shown that state virtual or digital libraries are evolving into websites that are loaded with free resources, subscription databases, and instructional tools. In this article, the author explores these evolving libraries based on the following questions: (1) How user-friendly are the state digital libraries?; (2) How do state digital…

  6. Generating "fragment-based virtual library" using pocket similarity search of ligand-receptor complexes.

    Science.gov (United States)

    Khashan, Raed S

    2015-01-01

    As the number of available ligand-receptor complexes is increasing, researchers are becoming more dedicated to mine these complexes to aid in the drug design and development process. We present free software which is developed as a tool for performing similarity search across ligand-receptor complexes for identifying binding pockets which are similar to that of a target receptor. The search is based on 3D-geometric and chemical similarity of the atoms forming the binding pocket. For each match identified, the ligand's fragment(s) corresponding to that binding pocket are extracted, thus forming a virtual library of fragments (FragVLib) that is useful for structure-based drug design. The program provides a very useful tool to explore available databases.

  7. Validation study of SRAC2006 code system based on evaluated nuclear data libraries for TRIGA calculations by benchmarking integral parameters of TRX and BAPL lattices of thermal reactors

    International Nuclear Information System (INIS)

    Khan, M.J.H.; Sarker, M.M.; Islam, S.M.A.

    2013-01-01

    Highlights: ► To validate the SRAC2006 code system for TRIGA neutronics calculations. ► TRX and BAPL lattices are treated as standard benchmarks for this purpose. ► To compare the calculated results with experiment as well as MCNP values in this study. ► The study demonstrates a good agreement with the experiment and the MCNP results. ► Thus, this analysis reflects the validation study of the SRAC2006 code system. - Abstract: The goal of this study is to present the validation study of the SRAC2006 code system based on evaluated nuclear data libraries ENDF/B-VII.0 and JENDL-3.3 for neutronics analysis of TRIGA Mark-II Research Reactor at AERE, Bangladesh. This study is achieved through the analysis of integral parameters of TRX and BAPL benchmark lattices of thermal reactors. In integral measurements, the thermal reactor lattices TRX-1, TRX-2, BAPL-UO 2 -1, BAPL-UO 2 -2 and BAPL-UO 2 -3 are treated as standard benchmarks for validating/testing the SRAC2006 code system as well as nuclear data libraries. The integral parameters of the said lattices are calculated using the collision probability transport code PIJ of the SRAC2006 code system at room temperature 20 °C based on the above libraries. The calculated integral parameters are compared to the measured values as well as the MCNP values based on the Chinese evaluated nuclear data library CENDL-3.0. It was found that in most cases, the values of integral parameters demonstrate a good agreement with the experiment and the MCNP results. In addition, the group constants in SRAC format for TRX and BAPL lattices in fast and thermal energy range respectively are compared between the above libraries and it was found that the group constants are identical with very insignificant difference. Therefore, this analysis reflects the validation study of the SRAC2006 code system based on evaluated nuclear data libraries JENDL-3.3 and ENDF/B-VII.0 and can also be essential to implement further neutronics calculations

  8. Contents Development of Library Signage Manual in Korea

    Directory of Open Access Journals (Sweden)

    In-Ja Ahn

    2011-12-01

    Full Text Available There is an increase in the need of an unified manual for library signage system, due to recent increase in library construction or remodeling. This paper, therefore, can be a basic research to develop library signage system manual. Based on an anual released from KLA and the sum of opinions of expert groups, this research proposes a concrete list of contents for library signage system manual as follows. First, there is a need of theoretical basis of library signage system. Second, for the actual practices of signage system, planning, check list, and standard terms shall be necessary.

  9. Contents Development of Library Signage Manual in Korea

    OpenAIRE

    In-Ja Ahn

    2011-01-01

    There is an increase in the need of an unified manual for library signage system, due to recent increase in library construction or remodeling. This paper, therefore, can be a basic research to develop library signage system manual. Based on an anual released from KLA and the sum of opinions of expert groups, this research proposes a concrete list of contents for library signage system manual as follows. First, there is a need of theoretical basis of library signage system. Second, for the ac...

  10. Development of automatic editing system for MCNP library 'autonj'

    International Nuclear Information System (INIS)

    Maekawa, Fujio; Sakurai, Kiyoshi; Kume, Etsuo; Nomura, Yasushi; Kosako, Kazuaki; Kawasaki, Nobuo; Naito, Yoshitaka

    1999-12-01

    As an activity of the MCNP High-Temperature Library Production Working Group under the Nuclear Code Evaluation Special Committee of Nuclear Code Committee, the automatic editing system for MCNP library 'autonj' was developed. The autonj includes the NJOY-97 code as its main body, and is a system that enables us to easily produce cross section libraries for MCNP from evaluated nuclear data files such as JENDL-3.2. A temperature dependent library at six temperature points based on JENDL-3.2 was produced by using autonj. The autonj system and the temperature dependent library were installed on the JAERI AP3000 computer. (author)

  11. The AHEC library program and consortia development in California.

    Science.gov (United States)

    Jensen, M A; Maddalena, B

    1986-07-01

    A brief history of the first Area Health Education Center (AHEC) Library Program in California is presented, with a description of methodology and results. The goals of this program were to develop and improve hospital library resources and services, to train hospital library personnel, and to promote resource sharing in a medically underserved area. The health sciences library consortium that evolved became a model for the ten other library consortia in the state. Based on AHEC's twelve years' experience with consortia, from 1973 to 1985, recommendations are made as to size, composition, leadership, outside funding, group participation, publicity, and linkages.

  12. Scribl: an HTML5 Canvas-based graphics library for visualizing genomic data over the web.

    Science.gov (United States)

    Miller, Chase A; Anthony, Jon; Meyer, Michelle M; Marth, Gabor

    2013-02-01

    High-throughput biological research requires simultaneous visualization as well as analysis of genomic data, e.g. read alignments, variant calls and genomic annotations. Traditionally, such integrative analysis required desktop applications operating on locally stored data. Many current terabyte-size datasets generated by large public consortia projects, however, are already only feasibly stored at specialist genome analysis centers. As even small laboratories can afford very large datasets, local storage and analysis are becoming increasingly limiting, and it is likely that most such datasets will soon be stored remotely, e.g. in the cloud. These developments will require web-based tools that enable users to access, analyze and view vast remotely stored data with a level of sophistication and interactivity that approximates desktop applications. As rapidly dropping cost enables researchers to collect data intended to answer questions in very specialized contexts, developers must also provide software libraries that empower users to implement customized data analyses and data views for their particular application. Such specialized, yet lightweight, applications would empower scientists to better answer specific biological questions than possible with general-purpose genome browsers currently available. Using recent advances in core web technologies (HTML5), we developed Scribl, a flexible genomic visualization library specifically targeting coordinate-based data such as genomic features, DNA sequence and genetic variants. Scribl simplifies the development of sophisticated web-based graphical tools that approach the dynamism and interactivity of desktop applications. Software is freely available online at http://chmille4.github.com/Scribl/ and is implemented in JavaScript with all modern browsers supported.

  13. Information about AER WG A on improvement, extension and validation of parametrized few-group libraries for VVER 440 and VVER 1000

    International Nuclear Information System (INIS)

    Mikolas, P.

    2010-01-01

    Joint AER Working Group A on 'Improvement, extension and validation of parameterized few-group libraries for WWER-440 and WWER-1000' and AER Working Group B on 'Core design' nineteenth meeting was hosted by VUJE a. s. in Modra - Harmonia (Slovakia) during the period of 20. to 22. April 2010. There were present altogether 12 participants from 8 member organizations and 9 papers were presented (8 of them in written form). Objectives of the meeting of WG A are: Issues connected with spectral calculations and few-groups libraries preparation, their accuracy and validation. Presentations were devoted to some aspects of transport and diffusion calculations and to the benchmark dealing with WWER-1000 core periphery power tilt. Tamas Parko (co-authors Istvan Pos and Sandor Patai Szabo) described in his presentation 'Application of Discontinuity factors in C-PORCA 7 code', Radoslav Zajac (co-authors Petr Darilek and Vladimir Necas) spoke about 'Fast Reactor Nodalisation in HELIOS Code', Gabriel Farkas presented 'Calculation of Spatial Weighting Functions of Ex-Core Neutron Detectors for WWER-440 Using Monte Carlo Approach' and Daniel Sprinzl (co-authors Vaclav Krysl, Pavel Mikolas and Jiri Svarny) provided a definition of a benchmark in ' 'MIDICORE' WWER-1000 core periphery power tilt benchmark proposal'. (Author)

  14. Performance Improvement with Web Based Database on Library Information System of Smk Yadika 5

    Directory of Open Access Journals (Sweden)

    Pualam Dipa Nusantara

    2015-12-01

    Full Text Available The difficulty in managing the data of books collection in the library is a problem that is often faced by the librarian that effect the quality of service. Arrangement and recording a collection of books in the file system of separate applications Word and Excel, as well as transaction handling borrowing and returning books, therehas been no integrated records. Library system can manage the book collection. This system can reduce the problems often experienced by library staff when serving students in borrowing books. There so frequent difficulty in managing the books that still in borrowed state. This system will also record a collection of late fees or lost library conducted by students (borrowers. The conclusion of this study is library performance can be better with the library system using web database.

  15. Enterprise Reference Library

    Science.gov (United States)

    Bickham, Grandin; Saile, Lynn; Havelka, Jacque; Fitts, Mary

    2011-01-01

    duplication costs. Most importantly, increasing collaboration across research groups provides unprecedented access to information relevant to NASA s mission. Conclusion: This project is an expansion and cost-effective leveraging of the existing JSC centralized library. Adding key word and author search capabilities and an alert function for notifications about new articles, based on users profiles, represent examples of future enhancements.

  16. Project GRACE A grid based search tool for the global digital library

    CERN Document Server

    Scholze, Frank; Vigen, Jens; Prazak, Petra; The Seventh International Conference on Electronic Theses and Dissertations

    2004-01-01

    The paper will report on the progress of an ongoing EU project called GRACE - Grid Search and Categorization Engine (http://www.grace-ist.org). The project participants are CERN, Sheffield Hallam University, Stockholm University, Stuttgart University, GL 2006 and Telecom Italia. The project started in 2002 and will finish in 2005, resulting in a Grid based search engine that will search across a variety of content sources including a number of electronic thesis and dissertation repositories. The Open Archives Initiative (OAI) is expanding and is clearly an interesting movement for a community advocating open access to ETD. However, the OAI approach alone may not be sufficiently scalable to achieve a truly global ETD Digital Library. Many universities simply offer their collections to the world via their local web services without being part of any federated system for archiving and even those dissertations that are provided with OAI compliant metadata will not necessarily be picked up by a centralized OAI Ser...

  17. RINGMesh: A programming library for developing mesh-based geomodeling applications

    Science.gov (United States)

    Pellerin, Jeanne; Botella, Arnaud; Bonneau, François; Mazuyer, Antoine; Chauvin, Benjamin; Lévy, Bruno; Caumon, Guillaume

    2017-07-01

    RINGMesh is a C++ open-source programming library for manipulating discretized geological models. It is designed to ease the development of applications and workflows that use discretized 3D models. It is neither a geomodeler, nor a meshing software. RINGMesh implements functionalities to read discretized surface-based or volumetric structural models and to check their validity. The models can be then exported in various file formats. RINGMesh provides data structures to represent geological structural models, either defined by their discretized boundary surfaces, and/or by discretized volumes. A programming interface allows to develop of new geomodeling methods, and to plug in external software. The goal of RINGMesh is to help researchers to focus on the implementation of their specific method rather than on tedious tasks common to many applications. The documented code is open-source and distributed under the modified BSD license. It is available at https://www.ring-team.org/index.php/software/ringmesh.

  18. MCNP and MATXS cross section libraries based on JENDL-3.3

    International Nuclear Information System (INIS)

    Kosako, Kazuaki; Konno, Chikara; Fukahori, Tokio; Shibata, Keiichi

    2003-01-01

    The continuous energy cross section library for the Monte Carlo transport code MCNP-4C, FSXLIB-J33, has been generated from the latest version of JENDL-3.3. The multigroup cross section library with the MATXS format, MATXS-J33, has been generated also from JENDL-3.3. Both libraries contain all nuclides in JENDL-3.3 and are processed at 300 K by the nuclear data processing system NJOY99. (author)

  19. A simple and efficient method for assembling TALE protein based on plasmid library.

    Science.gov (United States)

    Zhang, Zhiqiang; Li, Duo; Xu, Huarong; Xin, Ying; Zhang, Tingting; Ma, Lixia; Wang, Xin; Chen, Zhilong; Zhang, Zhiying

    2013-01-01

    DNA binding domain of the transcription activator-like effectors (TALEs) from Xanthomonas sp. consists of tandem repeats that can be rearranged according to a simple cipher to target new DNA sequences with high DNA-binding specificity. This technology has been successfully applied in varieties of species for genome engineering. However, assembling long TALE tandem repeats remains a big challenge precluding wide use of this technology. Although several new methodologies for efficiently assembling TALE repeats have been recently reported, all of them require either sophisticated facilities or skilled technicians to carry them out. Here, we described a simple and efficient method for generating customized TALE nucleases (TALENs) and TALE transcription factors (TALE-TFs) based on TALE repeat tetramer library. A tetramer library consisting of 256 tetramers covers all possible combinations of 4 base pairs. A set of unique primers was designed for amplification of these tetramers. PCR products were assembled by one step of digestion/ligation reaction. 12 TALE constructs including 4 TALEN pairs targeted to mouse Gt(ROSA)26Sor gene and mouse Mstn gene sequences as well as 4 TALE-TF constructs targeted to mouse Oct4, c-Myc, Klf4 and Sox2 gene promoter sequences were generated by using our method. The construction routines took 3 days and parallel constructions were available. The rate of positive clones during colony PCR verification was 64% on average. Sequencing results suggested that all TALE constructs were performed with high successful rate. This is a rapid and cost-efficient method using the most common enzymes and facilities with a high success rate.

  20. Starting a Research Data Management Program Based in a University Library

    Science.gov (United States)

    Henderson, Margaret E.; Knott, Teresa L.

    2015-01-01

    As the need for research data management grows, many libraries are considering adding data services to help with the research mission of their institution. The VCU Libraries created a position and hired a director of research data management in September 2013. The position was new to the libraries and the university. With the backing of the library administration, a plan for building relationships with VCU faculty, researchers, students, service and resource providers, including grant administrators, was developed to educate and engage the community in data management plan writing and research data management training. PMID:25611440

  1. Starting a research data management program based in a university library.

    Science.gov (United States)

    Henderson, Margaret E; Knott, Teresa L

    2015-01-01

    As the need for research data management grows, many libraries are considering adding data services to help with the research mission of their institution. The Virginia Commonwealth University (VCU) Libraries created a position and hired a director of research data management in September 2013. The position was new to the libraries and the university. With the backing of the library administration, a plan for building relationships with VCU faculty, researchers, students, service and resource providers, including grant administrators, was developed to educate and engage the community in data management plan writing and research data management training.

  2. Research Library

    Science.gov (United States)

    Los Alamos National Laboratory Research Library Search Site submit Contact Us | Remote Access Standards Theses/Dissertations Research Help Subject Guides Library Training Video Tutorials Alerts Research Library: delivering essential knowledge services for national security sciences since 1947 Los

  3. Challenges and Opportunities for Libraries in Pakistan

    OpenAIRE

    Shafiq UR, Rehman; Pervaiz, Ahmad

    2007-01-01

    Abstract: This paper, based on review of literature, observation, and informal conversations, discusses various challenges regarding finance, collection development, ICTs, human resources, library education, library association and research & development faced by library profession in Pakistan. The opportunities to meet these challenges have also been explored. Keywords: Library challenges and opportunities (Pakistan); Librarianship (Pakistan); Library issues; Library profession in Pa...

  4. Affirmation, acknowledgment of in-group responsibility, group-based guilt, and support for reparative measures.

    Science.gov (United States)

    Cehajić-Clancy, Sabina; Effron, Daniel A; Halperin, Eran; Liberman, Varda; Ross, Lee D

    2011-08-01

    Three studies, 2 conducted in Israel and 1 conducted in Bosnia and Herzegovina, demonstrated that affirming a positive aspect of the self can increase one's willingness to acknowledge in-group responsibility for wrongdoing against others, express feelings of group-based guilt, and consequently provide greater support for reparation policies. By contrast, affirming one's group, although similarly boosting feelings of pride, failed to increase willingness to acknowledge and redress in-group wrongdoing. Studies 2 and 3 demonstrated the mediating role of group-based guilt. That is, increased acknowledgment of in-group responsibility for out-group victimization produced increased feelings of guilt, which in turn increased support for reparation policies to the victimized group. Theoretical and applied implications are discussed.

  5. BiNChE: a web tool and library for chemical enrichment analysis based on the ChEBI ontology.

    Science.gov (United States)

    Moreno, Pablo; Beisken, Stephan; Harsha, Bhavana; Muthukrishnan, Venkatesh; Tudose, Ilinca; Dekker, Adriano; Dornfeldt, Stefanie; Taruttis, Franziska; Grosse, Ivo; Hastings, Janna; Neumann, Steffen; Steinbeck, Christoph

    2015-02-21

    Ontology-based enrichment analysis aids in the interpretation and understanding of large-scale biological data. Ontologies are hierarchies of biologically relevant groupings. Using ontology annotations, which link ontology classes to biological entities, enrichment analysis methods assess whether there is a significant over or under representation of entities for ontology classes. While many tools exist that run enrichment analysis for protein sets annotated with the Gene Ontology, there are only a few that can be used for small molecules enrichment analysis. We describe BiNChE, an enrichment analysis tool for small molecules based on the ChEBI Ontology. BiNChE displays an interactive graph that can be exported as a high-resolution image or in network formats. The tool provides plain, weighted and fragment analysis based on either the ChEBI Role Ontology or the ChEBI Structural Ontology. BiNChE aids in the exploration of large sets of small molecules produced within Metabolomics or other Systems Biology research contexts. The open-source tool provides easy and highly interactive web access to enrichment analysis with the ChEBI ontology tool and is additionally available as a standalone library.

  6. Improvement of the Response Time in an Open Source Audioconference Architecture Based on SIP Multicast Implemented with JainSIP, JainSDP and JGAP Libraries

    Directory of Open Access Journals (Sweden)

    Carlos M. Moreno

    2014-06-01

    Full Text Available Group services like the audioconference require a minimum level of quality of service for multicast sessions. This work proposes a new overlay multicast architecture based on SIP extensions and a genetic algorithm. The architecture consists of a SIP Extender client (SE, a Multicast Gateway Agent (MGA and a Multicast Manager (MM. The SE receives information about the most adequate MGA for it determined by a genetic algorithm inside the MM, then connects the chosen MGA and maintains connection with the MM itself. The genetic algorithm is implemented with JGAP(Java Genetic Algorithm Package libraries. The SE and MGA are programmed with JainSIP and JainSDP libraries which contain Java structures associated with the SIP protocol and session description. Some experiments over UTP wired and WiFi IEEE802.11n network were performed. Partial results with static and dynamic MGA selection show that, if we compare the joining and leaving time measured inside a station containing SE client programmed with JainSIP and JainSDP libraries versus SJphone proprietary client, the software engineering may have more influence than the medium access method in the response time for a potential group member. Even more, the genetic algorithm at the MM minimizes the response time at great scale.

  7. Investigating the use of a digital library in an inquiry-based undergraduate geology course

    Directory of Open Access Journals (Sweden)

    Xornam S. Apedoe

    2007-06-01

    Full Text Available This paper reports the findings of a qualitative research study designed to investigate the opportunities and obstacles presented by a digital library for supporting teaching and learning in an inquiry-based undergraduate geology course. Data for this study included classroom observations and field-notes of classroom practices, questionnaires, and audiotapes and transcripts of interviews conducted with student and instructor participants. The findings suggest that although both the instructor and students recognized a number of opportunities presented by the digital library to support teaching and learning (e.g., provides access to various types of data, they encountered a number of obstacles (e.g., difficulty with the search mechanism that discouraged them from taking advantage of the resources available. Recommendations are presented for (a developers of digital libraries, and (b instructors wishing to integrate use of a digital library for supporting their teaching and student learning in an inquiry-based course. Le présent article rend compte des conclusions d’une étude de recherche qualitative élaborée afin d’examiner les occasions et les obstacles que présente une bibliothèque numérique appuyant l’enseignement et l’apprentissage dans le cadre d’un cours de géologie de premier cycle axé sur la recherche. Les données pour cette étude comprenaient les observations effectuées en salle de classe et les notes d’excursion des pratiques en salle de classe, les questionnaires, les bandes audio ainsi que les transcriptions des entrevues menées auprès des étudiants et de l’instructeur participant. Les conclusions laissent entendre que bien que l’instructeur et les étudiants reconnaissent un certain nombre d’occasions que présente la bibliothèque numérique en appui à l’enseignement et à l’apprentissage (p. ex. accès à divers types de données, ils ont dû surmonter un certain nombre d’obstacles (p. ex

  8. A library based fitting method for visual reflectance spectroscopy of human skin

    Energy Technology Data Exchange (ETDEWEB)

    Verkruysse, Wim [Beckman Laser Institute, University of California, Irvine, CA 92612 (United States); Zhang Rong [Beckman Laser Institute, University of California, Irvine, CA 92612 (United States); Choi, Bernard [Beckman Laser Institute, University of California, Irvine, CA 92612 (United States); Lucassen, Gerald [Personal Care Institute, Philips Research, Prof Holstlaan 4, Eindhoven (Netherlands); Svaasand, Lars O [Department of Physical Electronics Norwegian University of Science and Technology, N-7491 Trondheim (Norway); Nelson, J Stuart [Beckman Laser Institute, University of California, Irvine, CA 92612 (United States)

    2005-01-07

    The diffuse reflectance spectrum of human skin in the visible region (400-800 nm) contains information on the concentrations of chromophores such as melanin and haemoglobin. This information may be extracted by fitting the reflectance spectrum with an optical diffusion based analytical expression applied to a layered skin model. With the use of the analytical expression, it is assumed that light transport is dominated by scattering. For port wine stain (PWS) and highly pigmented human skin, however, this assumption may not be valid resulting in a potentially large error in visual reflectance spectroscopy (VRS). Monte Carlo based techniques can overcome this problem but are currently too computationally intensive to be combined with previously used fitting procedures. The fitting procedure presented herein is based on a library search which enables the use of accurate reflectance spectra based on forward Monte Carlo simulations or diffusion theory. This allows for accurate VRS to characterize chromophore concentrations in PWS and highly pigmented human skin. The method is demonstrated using both simulated and measured reflectance spectra. An additional advantage of the method is that the fitting procedure is very fast.

  9. A library based fitting method for visual reflectance spectroscopy of human skin

    International Nuclear Information System (INIS)

    Verkruysse, Wim; Zhang Rong; Choi, Bernard; Lucassen, Gerald; Svaasand, Lars O; Nelson, J Stuart

    2005-01-01

    The diffuse reflectance spectrum of human skin in the visible region (400-800 nm) contains information on the concentrations of chromophores such as melanin and haemoglobin. This information may be extracted by fitting the reflectance spectrum with an optical diffusion based analytical expression applied to a layered skin model. With the use of the analytical expression, it is assumed that light transport is dominated by scattering. For port wine stain (PWS) and highly pigmented human skin, however, this assumption may not be valid resulting in a potentially large error in visual reflectance spectroscopy (VRS). Monte Carlo based techniques can overcome this problem but are currently too computationally intensive to be combined with previously used fitting procedures. The fitting procedure presented herein is based on a library search which enables the use of accurate reflectance spectra based on forward Monte Carlo simulations or diffusion theory. This allows for accurate VRS to characterize chromophore concentrations in PWS and highly pigmented human skin. The method is demonstrated using both simulated and measured reflectance spectra. An additional advantage of the method is that the fitting procedure is very fast

  10. A library based fitting method for visual reflectance spectroscopy of human skin

    Science.gov (United States)

    Verkruysse, Wim; Zhang, Rong; Choi, Bernard; Lucassen, Gerald; Svaasand, Lars O.; Nelson, J. Stuart

    2005-01-01

    The diffuse reflectance spectrum of human skin in the visible region (400-800 nm) contains information on the concentrations of chromophores such as melanin and haemoglobin. This information may be extracted by fitting the reflectance spectrum with an optical diffusion based analytical expression applied to a layered skin model. With the use of the analytical expression, it is assumed that light transport is dominated by scattering. For port wine stain (PWS) and highly pigmented human skin, however, this assumption may not be valid resulting in a potentially large error in visual reflectance spectroscopy (VRS). Monte Carlo based techniques can overcome this problem but are currently too computationally intensive to be combined with previously used fitting procedures. The fitting procedure presented herein is based on a library search which enables the use of accurate reflectance spectra based on forward Monte Carlo simulations or diffusion theory. This allows for accurate VRS to characterize chromophore concentrations in PWS and highly pigmented human skin. The method is demonstrated using both simulated and measured reflectance spectra. An additional advantage of the method is that the fitting procedure is very fast.

  11. Multispectral iris recognition based on group selection and game theory

    Science.gov (United States)

    Ahmad, Foysal; Roy, Kaushik

    2017-05-01

    A commercially available iris recognition system uses only a narrow band of the near infrared spectrum (700-900 nm) while iris images captured in the wide range of 405 nm to 1550 nm offer potential benefits to enhance recognition performance of an iris biometric system. The novelty of this research is that a group selection algorithm based on coalition game theory is explored to select the best patch subsets. In this algorithm, patches are divided into several groups based on their maximum contribution in different groups. Shapley values are used to evaluate the contribution of patches in different groups. Results show that this group selection based iris recognition

  12. A large synthetic peptide and phosphopeptide reference library for mass spectrometry–based proteomics

    NARCIS (Netherlands)

    Marx, H.; Lemeer, S.; Schliep, J.E.; Matheron, L.I.; Mohammed, S.; Cox, J.; Mann, M.; Heck, A.J.R.; Kuster, B.

    2013-01-01

    We present a peptide library and data resource of >100,000 synthetic, unmodified peptides and their phosphorylated counterparts with known sequences and phosphorylation sites. Analysis of the library by mass spectrometry yielded a data set that we used to evaluate the merits of different search

  13. Expanding the Intellectual Property Knowledge Base at University Libraries: Collaborating with Patent and Trademark Resource Centers

    Science.gov (United States)

    Wallace, Martin; Reinman, Suzanne

    2018-01-01

    Patent and Trademark Resource Centers are located in libraries throughout the U.S., with 43 being in academic libraries. With the importance of incorporating a knowledge of intellectual property (IP) and patent research in university curricula nationwide, this study developed and evaluated a partnership program to increase the understanding of IP…

  14. Evaluation of the quality of the college library websites in Iranian medical Universities based on the Stover model.

    Science.gov (United States)

    Nasajpour, Mohammad Reza; Ashrafi-Rizi, Hasan; Soleymani, Mohammad Reza; Shahrzadi, Leila; Hassanzadeh, Akbar

    2014-01-01

    Today, the websites of college and university libraries play an important role in providing the necessary services for clients. These websites not only allow the users to access different collections of library resources, but also provide them with the necessary guidance in order to use the information. The goal of this study is the quality evaluation of the college library websites in Iranian Medical Universities based on the Stover model. This study uses an analytical survey method and is an applied study. The data gathering tool is the standard checklist provided by Stover, which was modified by the researchers for this study. The statistical population is the college library websites of the Iranian Medical Universities (146 websites) and census method was used for investigation. The data gathering method was a direct access to each website and filling of the checklist was based on the researchers' observations. Descriptive and analytical statistics (Analysis of Variance (ANOVA)) were used for data analysis with the help of the SPSS software. The findings showed that in the dimension of the quality of contents, the highest average belonged to type one universities (46.2%) and the lowest average belonged to type three universities (24.8%). In the search and research capabilities, the highest average belonged to type one universities (48.2%) and the lowest average belonged to type three universities. In the dimension of facilities provided for the users, type one universities again had the highest average (37.2%), while type three universities had the lowest average (15%). In general the library websites of type one universities had the highest quality (44.2%), while type three universities had the lowest quality (21.1%). Also the library websites of the College of Rehabilitation and the College of Paramedics, of the Shiraz University of Medical Science, had the highest quality scores. The results showed that there was a meaningful difference between the quality

  15. Simultaneous digital quantification and fluorescence-based size characterization of massively parallel sequencing libraries.

    Science.gov (United States)

    Laurie, Matthew T; Bertout, Jessica A; Taylor, Sean D; Burton, Joshua N; Shendure, Jay A; Bielas, Jason H

    2013-08-01

    Due to the high cost of failed runs and suboptimal data yields, quantification and determination of fragment size range are crucial steps in the library preparation process for massively parallel sequencing (or next-generation sequencing). Current library quality control methods commonly involve quantification using real-time quantitative PCR and size determination using gel or capillary electrophoresis. These methods are laborious and subject to a number of significant limitations that can make library calibration unreliable. Herein, we propose and test an alternative method for quality control of sequencing libraries using droplet digital PCR (ddPCR). By exploiting a correlation we have discovered between droplet fluorescence and amplicon size, we achieve the joint quantification and size determination of target DNA with a single ddPCR assay. We demonstrate the accuracy and precision of applying this method to the preparation of sequencing libraries.

  16. Comparison of WIMS results using libraries based on new evaluated data files

    International Nuclear Information System (INIS)

    Trkov, A.; Ganesan, S.; Zidi, T.

    1996-01-01

    A number of selected benchmark experiments have been modelled with the WIMS-D/4 lattice code. Calculations were performed using multigroup libraries generated from a number of newly released evaluated data files. Data processing was done with the NJOY91.38 code. Since the data processing methods were the same in all cases, the results may serve to determine the impact on integral parameters due to differences in the basic data. The calculated integral parameters were also compared to the measured values. Observed differences were small, which means that there are no essential differences between the evaluated data libraries. The results of the analysis cannot serve to discriminate in terms of quality of the data between the evaluated data libraries considered. For the test cases considered the results with the new, unadjusted libraries are at least as good as those obtained with the old, adjusted WIMS library which is supplied with the code. (author). 16 refs, 3 tabs

  17. Results from the second Galaxy Serpent web-based table top exercise utilizing the concept of nuclear forensics libraries

    International Nuclear Information System (INIS)

    Borgardt, James; Canaday, Jodi; Chamberlain, David

    2017-01-01

    Galaxy Serpent is a unique, virtual, web-based international tabletop series of exercises designed to mature the concept of National Nuclear Forensics Libraries (NNFLs). Teams participating in the second version of the exercise were provided synthetic sealed radioactive source data used to compile a model NNFL which then served as a comparative instrument in hypothetical scenarios involving sources out of regulatory control, allowing teams to successfully down-select and determine whether investigated sources were consistent with holdings in their model library. The methodologies utilized and aggregate results of the exercise will be presented, along with challenges encountered and benefits realized. (author)

  18. Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry

    Science.gov (United States)

    2018-01-01

    Natural products are well known for their biological relevance, high degree of three-dimensionality, and access to areas of largely unexplored chemical space. To shape our understanding of the interaction between natural products and protein targets in the postgenomic era, we have used native mass spectrometry to investigate 62 potential protein targets for malaria using a natural-product-based fragment library. We reveal here 96 low-molecular-weight natural products identified as binding partners of 32 of the putative malarial targets. Seventy-nine (79) fragments have direct growth inhibition on Plasmodium falciparum at concentrations that are promising for the development of fragment hits against these protein targets. This adds a fragment library to the published HTS active libraries in the public domain. PMID:29436819

  19. ClimateQUAL® and Thinklets: Using ClimateQUAL® with Group Support Systems to Facilitate Discussion and Set Priorities for Organizational Change at Criss Library

    Directory of Open Access Journals (Sweden)

    Nora Hillyer

    2013-06-01

    Full Text Available Objective – This article discusses a series of actions taken by the Criss Library at the University of Nebraska at Omaha to implement organizational change, using the ClimateQUAL® survey and facilitated discussions with ThinkTank™ group decision software. The library had experienced significant changes over a five-year period, with a renovation of the facility and three reorganizations resulting in a 50% staff turnover. Recognizing the strain that years of construction and personnel changes had placed on the organization, there was a desire to uncover the mood of the employees and reveal the issues behind low morale, uneasiness, and fear.Methods – In November 2009, the library conducted a ClimateQUAL® survey to develop a baseline to assess the effectiveness of any changes. After the results were distributed to library faculty and staff, a series of two-hour facilitated discussions was held to gather opinions and ideas for solutions using thinkLets, a pattern language for reasoning toward a goal. The group support system ThinkTank™ software was loaded onto computers, and employees were able to add their ideas anonymously during the sessions. Finally, 12 employees (29% completed a four-question survey on their perceptions of the facilitated discussions.Results – The facilitated discussions returned 76 sub-themes in 12 categories: staffing and scheduling issues, staff unity/teamwork, communication, goodwill/morale, accountability, decision-making, policy issues, skills and training, leadership, ergonomics/physical work environment, respect, and bullying. An advisory team culled the 76 sub-themes into 40 improvement strategies. Five were implemented immediately, and the remaining 35 were scheduled to be presented to the faculty and staff via an online survey. Participants’ perceptions of the facilitated discussions were mixed. Eighty-three percent of respondents reported that they did not feel safe speaking out about issues, most

  20. Ligand efficiency based approach for efficient virtual screening of compound libraries.

    Science.gov (United States)

    Ke, Yi-Yu; Coumar, Mohane Selvaraj; Shiao, Hui-Yi; Wang, Wen-Chieh; Chen, Chieh-Wen; Song, Jen-Shin; Chen, Chun-Hwa; Lin, Wen-Hsing; Wu, Szu-Huei; Hsu, John T A; Chang, Chung-Ming; Hsieh, Hsing-Pang

    2014-08-18

    Here we report for the first time the use of fit quality (FQ), a ligand efficiency (LE) based measure for virtual screening (VS) of compound libraries. The LE based VS protocol was used to screen an in-house database of 125,000 compounds to identify aurora kinase A inhibitors. First, 20 known aurora kinase inhibitors were docked to aurora kinase A crystal structure (PDB ID: 2W1C); and the conformations of docked ligand were used to create a pharmacophore (PH) model. The PH model was used to screen the database compounds, and rank (PH rank) them based on the predicted IC50 values. Next, LE_Scale, a weight-dependant LE function, was derived from 294 known aurora kinase inhibitors. Using the fit quality (FQ = LE/LE_Scale) score derived from the LE_Scale function, the database compounds were reranked (PH_FQ rank) and the top 151 (0.12% of database) compounds were assessed for aurora kinase A inhibition biochemically. This VS protocol led to the identification of 7 novel hits, with compound 5 showing aurora kinase A IC50 = 1.29 μM. Furthermore, testing of 5 against a panel of 31 kinase reveals that it is selective toward aurora kinase A & B, with <50% inhibition for other kinases at 10 μM concentrations and is a suitable candidate for further development. Incorporation of FQ score in the VS protocol not only helped identify a novel aurora kinase inhibitor, 5, but also increased the hit rate of the VS protocol by improving the enrichment factor (EF) for FQ based screening (EF = 828), compared to PH based screening (EF = 237) alone. The LE based VS protocol disclosed here could be applied to other targets for hit identification in an efficient manner. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  1. A Validated MCNP(X) Cross Section Library based on JEFF 3.1

    International Nuclear Information System (INIS)

    Haeck, W.; Verboomen, B.

    2006-01-01

    ALEPH-LIB is a multi-temperature neutron transport library for standard use by MCNP(X) and ALEPH generated with ALEPH-DLG. This is an auxiliary computer code to ALEPH, the Monte Carlo burn-up code under development at SCK-CEN in collaboration with Ghent university. ALEPH-DLG automates the entire process of generating library files with NJOY and takes care of the first requirement of a validated application library: verify the processing. It produces tailor made NJOY input files using data from the original ENDF file (initial temperature, the fact if the nuclide is fissile or if it has unresolved resonances, etc.) When the library files have been generated, ALEPH-DLG will also process the output from NJOY by extracting all messages and warnings. If ALEPH-DLG finds anything out of the ordinary, it will either warn the user or perform corrective actions. The temperatures included in the ALEPH-LIB library are 300, 600, 900, 1200, 1500 and 1800 K. Library files were produced for the JEF 2.2, JEFF 3.0, JEFF 3.1, JENDL 3.3 and ENDF/B-VI.8 nuclear data libraries. This will be extended with ENDF/B-VII when it becomes available. This report deals with the JEFF 3.1 files included in ALEPH-LIB that are now released by the NEA-OECD.

  2. A Validated MCNP(X) Cross Section Library based on JEFF 3.1

    Energy Technology Data Exchange (ETDEWEB)

    Haeck, W; Verboomen, B

    2006-10-15

    ALEPH-LIB is a multi-temperature neutron transport library for standard use by MCNP(X) and ALEPH generated with ALEPH-DLG. This is an auxiliary computer code to ALEPH, the Monte Carlo burn-up code under development at SCK-CEN in collaboration with Ghent university. ALEPH-DLG automates the entire process of generating library files with NJOY and takes care of the first requirement of a validated application library: verify the processing. It produces tailor made NJOY input files using data from the original ENDF file (initial temperature, the fact if the nuclide is fissile or if it has unresolved resonances, etc.) When the library files have been generated, ALEPH-DLG will also process the output from NJOY by extracting all messages and warnings. If ALEPH-DLG finds anything out of the ordinary, it will either warn the user or perform corrective actions. The temperatures included in the ALEPH-LIB library are 300, 600, 900, 1200, 1500 and 1800 K. Library files were produced for the JEF 2.2, JEFF 3.0, JEFF 3.1, JENDL 3.3 and ENDF/B-VI.8 nuclear data libraries. This will be extended with ENDF/B-VII when it becomes available. This report deals with the JEFF 3.1 files included in ALEPH-LIB that are now released by the NEA-OECD.

  3. The Development of an Aza-C-Glycoside Library Based on a Tandem Staudinger/Aza-Wittig/Ugi Three-Component Reaction

    NARCIS (Netherlands)

    Wennekes, T.; Bonger, K.M.; Vogel, K.; Berg, van den S.A.; Strijland, A.; Donker-Koopman, W.E.; Aerts, J.; Marel, van der A.; Overkleeft, H.S.

    2012-01-01

    We report the tandem Staudinger/aza-Wittig/Ugi three-component reaction mediated synthesis of a 64-member compound library of aza-C-glycosides. The library is composed of four pyrrolidine and three piperidine scaffolds, onto which a number of functional groups is grafted to form seven sublibraries.

  4. 3D High Resolution Mesh Deformation Based on Multi Library Wavelet Neural Network Architecture

    Science.gov (United States)

    Dhibi, Naziha; Elkefi, Akram; Bellil, Wajdi; Amar, Chokri Ben

    2016-12-01

    This paper deals with the features of a novel technique for large Laplacian boundary deformations using estimated rotations. The proposed method is based on a Multi Library Wavelet Neural Network structure founded on several mother wavelet families (MLWNN). The objective is to align features of mesh and minimize distortion with a fixed feature that minimizes the sum of the distances between all corresponding vertices. New mesh deformation method worked in the domain of Region of Interest (ROI). Our approach computes deformed ROI, updates and optimizes it to align features of mesh based on MLWNN and spherical parameterization configuration. This structure has the advantage of constructing the network by several mother wavelets to solve high dimensions problem using the best wavelet mother that models the signal better. The simulation test achieved the robustness and speed considerations when developing deformation methodologies. The Mean-Square Error and the ratio of deformation are low compared to other works from the state of the art. Our approach minimizes distortions with fixed features to have a well reconstructed object.

  5. New directions in health sciences libraries in China.

    Science.gov (United States)

    Xie, Zhiyun; Zhang, Jianjing

    2018-04-16

    This article briefly describes the services provided by Chinese health science libraries and the factors which influence service provision. Driven by new technologies and national initiatives, the key services delivered by Chinese health libraries in the last 10 years have been research support services (such as research impact assessment, support for data management), evidence-based medicine, systematic reviews, the promotion of health information literacy, and the development of institutional repositories. J.M. © 2018 Health Libraries Group.

  6. An Automatic User Grouping Model for a Group Recommender System in Location-Based Social Networks

    Directory of Open Access Journals (Sweden)

    Elahe Khazaei

    2018-02-01

    Full Text Available Spatial group recommendation refers to suggesting places to a given set of users. In a group recommender system, members of a group should have similar preferences in order to increase the level of satisfaction. Location-based social networks (LBSNs provide rich content, such as user interactions and location/event descriptions, which can be leveraged for group recommendations. In this paper, an automatic user grouping model is introduced that obtains information about users and their preferences through an LBSN. The preferences of the users, proximity of the places the users have visited in terms of spatial range, users’ free days, and the social relationships among users are extracted automatically from location histories and users’ profiles in the LBSN. These factors are combined to determine the similarities among users. The users are partitioned into groups based on these similarities. Group size is the key to coordinating group members and enhancing their satisfaction. Therefore, a modified k-medoids method is developed to cluster users into groups with specific sizes. To evaluate the efficiency of the proposed method, its mean intra-cluster distance and its distribution of cluster sizes are compared to those of general clustering algorithms. The results reveal that the proposed method compares favourably with general clustering approaches, such as k-medoids and spectral clustering, in separating users into groups of a specific size with a lower mean intra-cluster distance.

  7. Usage Analysis for the Identification of Research Trends in Digital Libraries; Keepers of the Crumbling Culture: What Digital Preservation Can Learn from Library History; Patterns of Journal Use by Scientists through Three Evolutionary Phases; Developing a Content Management System-Based Web Site; Exploring Charging Models for Digital Cultural Heritage in Europe; Visions: The Academic Library in 2012.

    Science.gov (United States)

    Bollen, Johan; Vemulapalli, Soma Sekara; Xu, Weining; Luce, Rick; Marcum, Deanna; Friedlander, Amy; Tenopir, Carol; Grayson, Matt; Zhang, Yan; Ebuen, Mercy; King, Donald W.; Boyce, Peter; Rogers, Clare; Kirriemuir, John; Tanner, Simon; Deegan, Marilyn; Marcum, James W.

    2003-01-01

    Includes six articles that discuss use analysis and research trends in digital libraries; library history and digital preservation; journal use by scientists; a content management system-based Web site for higher education in the United Kingdom; cost studies for transitioning to digitized collections in European cultural institutions; and the…

  8. Comprehensive evaluation of SNP identification with the Restriction Enzyme-based Reduced Representation Library (RRL method

    Directory of Open Access Journals (Sweden)

    Du Ye

    2012-02-01

    Full Text Available Abstract Background Restriction Enzyme-based Reduced Representation Library (RRL method represents a relatively feasible and flexible strategy used for Single Nucleotide Polymorphism (SNP identification in different species. It has remarkable advantage of reducing the complexity of the genome by orders of magnitude. However, comprehensive evaluation for actual efficacy of SNP identification by this method is still unavailable. Results In order to evaluate the efficacy of Restriction Enzyme-based RRL method, we selected Tsp 45I enzyme which covers 266 Mb flanking region of the enzyme recognition site according to in silico simulation on human reference genome, then we sequenced YH RRL after Tsp 45I treatment and obtained reads of which 80.8% were mapped to target region with an 20-fold average coverage, about 96.8% of target region was covered by at least one read and 257 K SNPs were identified in the region using SOAPsnp software. Compared with whole genome resequencing data, we observed false discovery rate (FDR of 13.95% and false negative rate (FNR of 25.90%. The concordance rate of homozygote loci was over 99.8%, but that of heterozygote were only 92.56%. Repeat sequences and bases quality were proved to have a great effect on the accuracy of SNP calling, SNPs in recognition sites contributed evidently to the high FNR and the low concordance rate of heterozygote. Our results indicated that repeat masking and high stringent filter criteria could significantly decrease both FDR and FNR. Conclusions This study demonstrates that Restriction Enzyme-based RRL method was effective for SNP identification. The results highlight the important role of bias and the method-derived defects represented in this method and emphasize the special attentions noteworthy.

  9. Beyond Traditional Literacy Instruction: Toward an Account-Based Literacy Training Curriculum in Libraries

    Science.gov (United States)

    Cirella, David

    2012-01-01

    A diverse group, account-based services include a wide variety of sites commonly used by patrons, including online shopping sites, social networks, photo- and video-sharing sites, banking and financial sites, government services, and cloud-based storage. Whether or not a piece of information is obtainable online must be considered when creating…

  10. 100 group displacement cross sections from RECOIL data base

    International Nuclear Information System (INIS)

    Gopalakrishnan, V.

    1995-01-01

    Displacement cross sections in 100 neutron energy groups were calculated from the RECOIL data base using the RECOIL program, for use in DPA (Displacement Per Atom) calculations for FBTR and PFBR materials. 100 group displacement cross sections were calculated using RECOIL-Data Base and RECOIL Program. Modifications were made in the data base to reduce space requirement, and in the program for easy handling on a PC. 2 refs

  11. Group-Based Active Learning of Classification Models.

    Science.gov (United States)

    Luo, Zhipeng; Hauskrecht, Milos

    2017-05-01

    Learning of classification models from real-world data often requires additional human expert effort to annotate the data. However, this process can be rather costly and finding ways of reducing the human annotation effort is critical for this task. The objective of this paper is to develop and study new ways of providing human feedback for efficient learning of classification models by labeling groups of examples. Briefly, unlike traditional active learning methods that seek feedback on individual examples, we develop a new group-based active learning framework that solicits label information on groups of multiple examples. In order to describe groups in a user-friendly way, conjunctive patterns are used to compactly represent groups. Our empirical study on 12 UCI data sets demonstrates the advantages and superiority of our approach over both classic instance-based active learning work, as well as existing group-based active-learning methods.

  12. WIMS/ABBN library based on the fond-2 evaluated files

    International Nuclear Information System (INIS)

    Jerdev, G.; Zabrodskaia, S.; Tsiboulia, A.; Koscheev, V.

    2001-01-01

    Description of a new system WIMS/ABBN is presented. It includes updated libraries of the WIMS/D4 code. The report involves sources and method of their creation, analysis and comparison of results at different tests also. Second path of the work is the development of the burnup library at WIMS system. As the result it was made a new system of burnup which new capabilities are shown. (authors)

  13. Design of redundant array of independent DVD libraries based on iSCSI

    Science.gov (United States)

    Chen, Yupeng; Pan, Longfa

    2003-04-01

    This paper presents a new approach to realize the redundant array of independent DVD libraries (RAID-LoIP) by using the iSCSI technology and traditional RAID algorithms. Our design reaches the high performance of optical storage system with following features: large storage size, highly accessing rate, random access, long distance of DVD libraries, block I/O storage, long storage life. Our RAID-LoIP system can be a good solution for broadcasting media asset storage system.

  14. A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins.

    Science.gov (United States)

    Joshi, Priyanka; Chia, Sean; Habchi, Johnny; Knowles, Tuomas P J; Dobson, Christopher M; Vendruscolo, Michele

    2016-03-14

    The aggregation process of intrinsically disordered proteins (IDPs) has been associated with a wide range of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. Currently, however, no drug in clinical use targets IDP aggregation. To facilitate drug discovery programs in this important and challenging area, we describe a fragment-based approach of generating small-molecule libraries that target specific IDPs. The method is based on the use of molecular fragments extracted from compounds reported in the literature to inhibit of the aggregation of IDPs. These fragments are used to screen existing large generic libraries of small molecules to form smaller libraries specific for given IDPs. We illustrate this approach by describing three distinct small-molecule libraries to target, Aβ, tau, and α-synuclein, which are three IDPs implicated in Alzheimer's and Parkinson's diseases. The strategy described here offers novel opportunities for the identification of effective molecular scaffolds for drug discovery for neurodegenerative disorders and to provide insights into the mechanism of small-molecule binding to IDPs.

  15. CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening.

    Science.gov (United States)

    Köferle, Anna; Worf, Karolina; Breunig, Christopher; Baumann, Valentin; Herrero, Javier; Wiesbeck, Maximilian; Hutter, Lukas H; Götz, Magdalena; Fuchs, Christiane; Beck, Stephan; Stricker, Stefan H

    2016-11-14

    The bacterial CRISPR system is fast becoming the most popular genetic and epigenetic engineering tool due to its universal applicability and adaptability. The desire to deploy CRISPR-based methods in a large variety of species and contexts has created an urgent need for the development of easy, time- and cost-effective methods enabling large-scale screening approaches. Here we describe CORALINA (comprehensive gRNA library generation through controlled nuclease activity), a method for the generation of comprehensive gRNA libraries for CRISPR-based screens. CORALINA gRNA libraries can be derived from any source of DNA without the need of complex oligonucleotide synthesis. We show the utility of CORALINA for human and mouse genomic DNA, its reproducibility in covering the most relevant genomic features including regulatory, coding and non-coding sequences and confirm the functionality of CORALINA generated gRNAs. The simplicity and cost-effectiveness make CORALINA suitable for any experimental system. The unprecedented sequence complexities obtainable with CORALINA libraries are a necessary pre-requisite for less biased large scale genomic and epigenomic screens.

  16. Libraries and Accessibility: Istanbul Public Libraries Case

    Directory of Open Access Journals (Sweden)

    Gül Yücel

    2016-12-01

    Full Text Available In the study; the assessment of accessibility has been conducted in Istanbul public libraries within the scope of public area. Public libraries commonly serve with its user of more than 20 million in total, spread to the general of Turkey, having more than one thousand branches in the centrums and having more than one million registered members. The building principles and standards covering the subjects such as the selection of place, historical and architectural specification of the region, distance to the centre of population and design in a way that the disabled people could benefit from the library services fully have been determined with regulations in the construction of new libraries. There are works for the existent libraries such as access for the disabled, fire safety precautions etc. within the scope of the related standards. Easy access by everyone is prioritized in the public libraries having a significant role in life-long learning. The purpose of the study is to develop solution suggestions for the accessibility problems in the public libraries. The study based on the eye inspection and assessments carried out within the scope of accessibility in the public libraries subsidiary to Istanbul Culture and Tourism Provincial Directorate Library and Publications Department within the provincial borders of Istanbul. The arrangements such as reading halls, study areas, book shelves etc. have been examined within the frame of accessible building standards. Building entrances, ramps and staircases, horizontal and vertical circulation of building etc. have been taken into consideration within the scope of accessible building standards. The subjects such as the reading and studying areas and book shelf arrangements for the library have been assessed within the scope of specific buildings. There are a total of 34 public libraries subsidiary to Istanbul Culture and Tourism Provincial Directorate on condition that 20 ea. of them are in the

  17. Experience in Computer-Assisted XML-Based Modelling in the Context of Libraries

    CERN Document Server

    Niinimäki, M

    2003-01-01

    In this paper, we introduce a software called Meta Data Visualisation (MDV) that (i) assists the user with a graphical user interface in the creation of his specific document types, (ii) creates a database according to these document types, (iii) allows the user to browse the database, and (iv) uses native XML presentation of the data in order to allow queries or data to be exported to other XML-based systems. We illustrate the use of MDV and XML modelling using library-related examples to build a bibliographic database. In our opinion, creating document type descriptions corresponds to conceptual and logical database design in a database design process. We consider that this design can be supported with a suitable set of tools that help the designer concentrate on conceptual issues instead of implementation issues. Our hypothesis is that using the methodology presented in this paper we can create XML databases that are useful and relevant, and with which MDV works as a user interface.

  18. Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds.

    Science.gov (United States)

    Prosdocimi, Tommaso; Mollica, Luca; Donini, Stefano; Semrau, Marta S; Lucarelli, Anna Paola; Aiolfi, Egidio; Cavalli, Andrea; Storici, Paola; Alfei, Silvana; Brullo, Chiara; Bruno, Olga; Parisini, Emilio

    2018-05-01

    Selected members of the large rolipram-related GEBR family of type 4 phosphodiesterase (PDE4) inhibitors have been shown to facilitate long-term potentiation and to improve memory functions without causing emetic-like behavior in rodents. Despite their micromolar-range binding affinities and their promising pharmacological and toxicological profiles, few if any structure-activity relationship studies have been performed to elucidate the molecular bases of their action. Here, we report the crystal structure of a number of GEBR library compounds in complex with the catalytic domain of PDE4D as well as their inhibitory profiles for both the long PDE4D3 isoform and the catalytic domain alone. Furthermore, we assessed the stability of the observed ligand conformations in the context of the intact enzyme using molecular dynamics simulations. The longer and more flexible ligands appear to be capable of forming contacts with the regulatory portion of the enzyme, thus possibly allowing some degree of selectivity between the different PDE4 isoforms.

  19. Atomic Energy Research working group a on improvement extension and validation of parametrized FEW-group libraries for WWER-440 and WWER-1000

    International Nuclear Information System (INIS)

    Svarny, J.

    1998-01-01

    The AER Working Groups A and B held its sixth meeting at SKODA JS, Plzen in April 28 and 29, 1998. There were altogether 13 participants from 6 member organizations. The list of participants and the list of papers are attached. (Author)

  20. DOSCROS81. ECN Cross-Section Library for neutron dosimetry. Summary of contents and documentation

    International Nuclear Information System (INIS)

    Lemmel, H.D.

    1982-01-01

    This document summarizes the contents and documentation of the Cross Section Library DOSCROS81 (640 groups in an extended SAND-II format). The library is based on ENDF/B-5 dosimetry file, supplemented with some other evaluations. The total number of reaction cross section sets incorporated in this library is 70 (+3 cover cross section sets). The entire library can be obtained free of charge from the IAEA Nuclear Data Section. A revised version is called DOSCROS81A. (author)

  1. The self-regulatory role of anticipated group-based shame and guilt in inhibiting in-group favoritism

    NARCIS (Netherlands)

    Shepherd, Lee; Spears, Russell; Manstead, Antony Stephen

    2013-01-01

    In three studies, we examined whether the anticipation of group-based guilt and shame inhibits in-group favoritism. In Studies 1 and 2, anticipated group-based shame negatively predicted in-group favoritism; in neither study did anticipated group-based guilt uniquely predict in-group favoritism. In

  2. SCHOOL COMMUNITY PERCEPTION OF LIBRARY APPS AGAINTS LIBRARY EMPOWERMENT

    Directory of Open Access Journals (Sweden)

    Achmad Riyadi Alberto

    2017-07-01

    Full Text Available Abstract. This research is motivated by the development of information and communication technology (ICT in the library world so rapidly that allows libraries in the present to develop its services into digital-based services. This study aims to find out the school community’s perception of library apps developed by Riche Cynthia Johan, Hana Silvana, and Holin Sulistyo and its influence on library empowerment at the library of SD Laboratorium Percontohan UPI Bandung. Library apps in this research belong to the context of m-libraries, which is a library that meets the needs of its users by using mobile platforms such as smartphones,computers, and other mobile devices. Empowerment of library is the utilization of all aspects of the implementation of libraries to the best in order to achieve the expected goals. An analysis of the schoolcommunity’s perception of library apps using the Technology Acceptance Model (TAM includes: ease of use, usefulness, usability, usage trends, and real-use conditions. While the empowerment of the library includes aspects: information empowerment, empowerment of learning resources, empowerment of human resources, empowerment of library facilities, and library promotion. The research method used in this research is descriptive method with quantitative approach. Population and sample in this research is school community at SD Laboratorium Percontohan UPI Bandung. Determination of sample criteria by using disproportionate stratified random sampling with the number of samples of 83 respondents. Data analysis using simple linear regression to measure the influence of school community perception about library apps to library empowerment. The result of data analysis shows that there is influence between school community perception about library apps to library empowerment at library of SD Laboratorium Percontohan UPI Bandung which is proved by library acceptance level and library empowerment improvement.

  3. Group Recommendation Systems Based on External Social-Trust Networks

    Directory of Open Access Journals (Sweden)

    Guang Fang

    2018-01-01

    Full Text Available With the development of social networks and online mobile communities, group recommendation systems support users’ interaction with similar interests or purposes with others. We often provide some advices to the close friends, such as listening to favorite music and sharing favorite dishes. However, users’ personalities have been ignored by the traditional group recommendation systems while the majority is satisfied. In this paper, a method of group recommendation based on external social-trust networks is proposed, which builds a group profile by analyzing not only users’ preferences, but also the social relationships between members inside and outside of the group. We employ the users’ degree of disagreement to adjust group preference rating by external information of social-trust network. Moreover, having a discussion about different social network utilization ratio, we proposed a method to work for smaller group size. The experimental results show that the proposed method has consistently higher precision and leads to satisfactory recommendations for groups.

  4. NJOY processed multigroup library for fast reactor applications and point data library for MCNP - Experience and validation

    International Nuclear Information System (INIS)

    Kim Jung-Do; Gil Choong-Sup

    1996-01-01

    JEF-1-based 50-group cross section library for fast reactor applications and point data library for continuous-energy Monte Carlo code MCNP have been generated using NJOY91.38 system. They have been examined by analyzing measured integral quantities such as criticality and central reaction rate ratios for 8 small fast critical assemblies. (author). 9 refs, 2 figs, 10 tabs

  5. Performance of the libraries in Isfahan University of Medical Sciences based on the EFQM model.

    Science.gov (United States)

    Karimi, Saeid; Atashpour, Bahareh; Papi, Ahmad; Nouri, Rasul; Hasanzade, Akbar

    2014-01-01

    Performance measurement is inevitable for university libraries. Hence, planning and establishing a constant and up-to-date measurement system is required for the libraries, especially the university libraries. The primary studies and analyses reveal that the EFQM Excellence Model has been efficient, and the administrative reform program has focused on the implementation of this model. Therefore, on the basis of these facts as well as the need for a measurement system, the researchers measured the performance of libraries in schools and hospitals supported by Isfahan University of Medical Sciences, using the EFQM Organizational Excellence Model. This descriptive research study was carried out by a cross-sectional survey method in 2011. This research study included librarians and library directors of Isfahan University of Medical Sciences (70 people). The validity of the instrument was measured by the specialists in the field of Management and Library Science. To measure the reliability of the questionnaire, the Cronbach's alpha coefficient value was measured (0.93). The t-test, ANOVA, and Spearman's rank correlation coefficient were used for measurements. The data were analyzed by SPSS. Data analysis revealed that the mean score of the performance measurement for the libraries under study and between nine dimensions the highest score was 65.3% for leadership dimension and the lowest scores were 55.1% for people and 55.1% for society results. In general, using the ninth EFQM model the average level of all dimensions, which is in good agreement with normal values, was assessed. However, compared to other results, the criterion people and society results were poor. It is Recommended by forming the expert committee on criterion people and society results by individuals concerned with the various conferences and training courses to improve the aspects.

  6. Assessment of Degree of Applicability of Benchmarks for Gadolinium Using KENO V.a and the 238-Group SCALE Cross-Section Library

    Energy Technology Data Exchange (ETDEWEB)

    Goluoglu, S.

    2003-12-01

    A review of the degree of applicability of benchmarks containing gadolinium using the computer code KENO V.a and the gadolinium cross sections from the 238-group SCALE cross-section library has been performed for a system that contains {sup 239}Pu, H{sub 2}O, and Gd{sub 2}O{sub 3}. The system (practical problem) is a water-reflected spherical mixture that represents a dry-out condition on the bottom of a sludge receipt and adjustment tank around steam coils. Due to variability of the mixture volume and the H/{sup 239}Pu ratio, approximations to the practical problem, referred to as applications, have been made to envelop possible ranges of mixture volumes and H/{sup 239}Pu ratios. A newly developed methodology has been applied to determine the degree of applicability of benchmarks as well as the penalty that should be added to the safety margin due to insufficient benchmarks.

  7. Generation of Matxs-formated nuclear data libraries

    International Nuclear Information System (INIS)

    Vontobel, P.

    1989-01-01

    Using the NJOY nuclear data processing system, three multigroup MATXS-formated nuclear data libraries were generated based on the European data files JEF-1 and EFF-1. After processing with TRAMIX, TRANSX, or TRANSX-CTR these libraries can be red into most transport and diffusion codes. For the neutron analysis of gas-cooled or water moderated thermal reactor systems (including high converter PWR's) a 70-group WIMS-BOXER structured library was generated. A general purpose fine group library in 308 groups is provided for thermal as well as for fast reactor systems. A coupled 175 neutron/42 photon-group library in VITAMIN-J structure was created for the analysis of shielding problems and fusion blanket design. A problem found when using CRAY's CFT77 compiler to implement NJOY87 is discussed. The problem of irregular selfshielding factors from UNRESR for some isotopes and (σ 0 , material temperature)-combinations in the unresolved resonance range is addressed

  8. Synthesis and systematic evaluation of dark resonance energy transfer (DRET)-based library and its application in cell imaging.

    Science.gov (United States)

    Su, Dongdong; Teoh, Chai Lean; Kang, Nam-Young; Yu, Xiaotong; Sahu, Srikanta; Chang, Young-Tae

    2015-03-01

    In this paper, we report a new strategy for constructing a dye library with large Stokes shifts. By coupling a dark donor with BODIPY acceptors of tunable high quantum yield, a novel dark resonance energy transfer (DRET)-based library, named BNM, has been synthesized. Upon excitation of the dark donor (BDN) at 490 nm, the absorbed energy is transferred to the acceptor (BDM) with high efficiency, which was tunable in a broad range from 557 nm to 716 nm, with a high quantum yield of up to 0.8. It is noteworthy to mention that the majority of the non-radiative energy loss of the donor was converted into the acceptor's fluorescence output with a minimum leak of donor emission. Fluorescence imaging tested in live cells showed that the BNM compounds are cell-permeable and can also be employed for live-cell imaging. This is a new library which can be excited through a dark donor allowing for strong fluorescence emission in a wide range of wavelengths. Thus, the BNM library is well suited for high-throughput screening or multiplex experiments in biological applications by using a single laser excitation source. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Group-Based Life Design Counseling in an Italian Context

    Science.gov (United States)

    Di Fabio, Annamaria; Maree, Jacobus Gideon

    2012-01-01

    This study examined the effectiveness of group-based Life Design Counseling using the Career-Story Interview. Written exercises were used to implement the seven topics in the Career-Story Interview. The present study employed an experimental design that involved two groups of Italian entrepreneurs from the agricultural and trade sectors, namely an…

  10. School-Based Adolescent Groups: The Sail Model.

    Science.gov (United States)

    Thompson, John L.; And Others

    The manual outlines the processes, policies, and actual program implementation of one component of a Minnesota program for emotionally disturbed adolescents (Project SAIL): the development of school-based therapy/intervention groups. The characteristics of SAIL students are described, and some considerations involved in providing group services…

  11. GROUP POLICY BASED AUTHENTICATION ON INCOMING CALLS FOR ANDROID SMARTPHONES

    OpenAIRE

    Sunita M. Kumbhar, Prof. Z.M Shaikh

    2016-01-01

    The numbers of Smartphone users increasing day by day. Hence, there is need to propose advanced Group Policy based Authentication for incoming calls for Android phone. Android platform provides a variety of functions that support the programming of face recognition, as in image processing. Group policy based authentication scheme increases the security which restricts the access of incoming call form un-authorized user. To solve problems, related to face recognition should be applied in the p...

  12. Visual training improves perceptual grouping based on basic stimulus features.

    Science.gov (United States)

    Kurylo, Daniel D; Waxman, Richard; Kidron, Rachel; Silverstein, Steven M

    2017-10-01

    Training on visual tasks improves performance on basic and higher order visual capacities. Such improvement has been linked to changes in connectivity among mediating neurons. We investigated whether training effects occur for perceptual grouping. It was hypothesized that repeated engagement of integration mechanisms would enhance grouping processes. Thirty-six participants underwent 15 sessions of training on a visual discrimination task that required perceptual grouping. Participants viewed 20 × 20 arrays of dots or Gabor patches and indicated whether the array appeared grouped as vertical or horizontal lines. Across trials stimuli became progressively disorganized, contingent upon successful discrimination. Four visual dimensions were examined, in which grouping was based on similarity in luminance, color, orientation, and motion. Psychophysical thresholds of grouping were assessed before and after training. Results indicate that performance in all four dimensions improved with training. Training on a control condition, which paralleled the discrimination task but without a grouping component, produced no improvement. In addition, training on only the luminance and orientation dimensions improved performance for those conditions as well as for grouping by color, on which training had not occurred. However, improvement from partial training did not generalize to motion. Results demonstrate that a training protocol emphasizing stimulus integration enhanced perceptual grouping. Results suggest that neural mechanisms mediating grouping by common luminance and/or orientation contribute to those mediating grouping by color but do not share resources for grouping by common motion. Results are consistent with theories of perceptual learning emphasizing plasticity in early visual processing regions.

  13. MCNP4c JEFF-3.1 Based Libraries. Eccolib-Jeff-3.1 libraries; Les bibliotheques Eccolib-Jeff-3.1

    Energy Technology Data Exchange (ETDEWEB)

    Sublet, J.Ch

    2006-07-01

    Continuous-energy and multi-temperatures MCNP Ace types libraries, derived from the Joint European Fusion-Fission JEFF-3.1 evaluations, have been generated using the NJOY-99.111 processing code system. They include the continuous-energy neutron JEFF-3.1/General Purpose, JEFF-3.1/Activation-Dosimetry and thermal S({alpha},{beta}) JEFF-3.1/Thermal libraries and data tables. The processing steps and features are explained together with the Quality Assurance processes and records linked to the generation of such multipurpose libraries. (author)

  14. Applying DEA Technique to Library Evaluation in Academic Research Libraries.

    Science.gov (United States)

    Shim, Wonsik

    2003-01-01

    This study applied an analytical technique called Data Envelopment Analysis (DEA) to calculate the relative technical efficiency of 95 academic research libraries, all members of the Association of Research Libraries. DEA, with the proper model of library inputs and outputs, can reveal best practices in the peer groups, as well as the technical…

  15. Standards-based teaching and educational digital libraries as innovations: Undergraduate science faculty in the adoption process

    Science.gov (United States)

    Ridgway, Judith Sulkes

    This study describes undergraduate science faculty in terms of their feelings of preparedness for and their use of standards-based teaching methods, their stages of concern related to Educational Digital Libraries (EDLs), and their adoption and diffusion of both innovations. These innovations may have a synergistic relationship that may result in enhanced adoption of both. The investigation began with a series of group meetings with life science, chemistry, physics, and geology faculty from a 2-year and a 4-year institution. Faculty were introduced to dimensions of standards-based teaching and examples of EDLs. Faculty completed the Demographics and Experience Questionnaire, the Standards-Based Teaching Instrument, and the Stages of Concern Questionnaire (SoCQ). Semi-structured interviews containing literature-based questions were conducted with one faculty member from each discipline from the 2-year and 4-year institutions. Document analyses were performed on mission/goal web-based statements for the institutions and their science departments. Triangulated data were used to construct individual faculty case studies based on four facets: background, standards-based teaching profile, EDLs profile, and rate of innovation diffusion. The individual case studies were used to perform cross-case analyses by type of institution, discipline, and locus of control. Individual case studies and cross-case analyses suggest the following conclusions: (a) faculty felt prepared to use and frequently used textbooks as a reference, (b) feelings of preparedness and frequency of use of standards-based teaching categories may be related to discipline, (c) all faculty had relatively high awareness and informational EDL concerns, and (d) faculty central to the locus of control were more likely to use methods to develop student conceptual understanding, use inquiry methods, and be agents of change. A grounded theoretical model connects study results with literature related to educational

  16. Modernization of Cross Section Library for VVER-1000 Type Reactors Internals and Pressure Vessel Dosimetry

    Directory of Open Access Journals (Sweden)

    Voloschenko Andrey

    2016-01-01

    Full Text Available The broad-group library BGL1000_B7 for neutron and gamma transport calculations in VVER-1000 internals, RPV and shielding was carried out on a base of fine-group library v7-200n47g from SCALE-6 system. The comparison of the library BGL1000_B7 with the library v7-200n47g and the library BGL1000 (the latter is using for VVER-1000 calculations is demonstrated on several calculation and experimental tests.

  17. Group Contribution Based Process Flowsheet Synthesis, Design and Modelling

    DEFF Research Database (Denmark)

    d'Anterroches, Loïc; Gani, Rafiqul

    2004-01-01

    This paper presents a process-group-contribution Method to model. simulate and synthesize a flowsheet. The process-group based representation of a flowsheet together with a process "property" model are presented. The process-group based synthesis method is developed on the basis of the computer...... aided molecular design methods and gives the ability to screen numerous process alternatives without the need to use the rigorous process simulation models. The process "property" model calculates the design targets for the generated flowsheet alternatives while a reverse modelling method (also...... developed) determines the design variables matching the target. A simple illustrative example highlighting the main features of the methodology is also presented....

  18. Analysis of 16S libraries of mouse gastrointestinal microflora reveals a large new group of mouse intestinal bacteria.

    Science.gov (United States)

    Salzman, Nita H; de Jong, Hendrik; Paterson, Yvonne; Harmsen, Hermie J M; Welling, Gjalt W; Bos, Nicolaas A

    2002-11-01

    Total genomic DNA from samples of intact mouse small intestine, large intestine, caecum and faeces was used as template for PCR amplification of 16S rRNA gene sequences with conserved bacterial primers. Phylogenetic analysis of the amplification products revealed 40 unique 16S rDNA sequences. Of these sequences, 25% (10/40) corresponded to described intestinal organisms of the mouse, including Lactobacillus spp., Helicobacter spp., segmented filamentous bacteria and members of the altered Schaedler flora (ASF360, ASF361, ASF502 and ASF519); 75% (30/40) represented novel sequences. A large number (11/40) of the novel sequences revealed a new operational taxonomic unit (OTU) belonging to the Cytophaga-Flavobacter-Bacteroides phylum, which the authors named 'mouse intestinal bacteria'. 16S rRNA probes were developed for this new OTU. Upon analysis of the novel sequences, eight were found to cluster within the Eubacterium rectale-Clostridium coccoides group and three clustered within the Bacteroides group. One of the novel sequences was distantly related to Verrucomicrobium spinosum and one was distantly related to Bacillus mycoides. Oligonucleotide probes specific for the 16S rRNA of these novel clones were generated. Using a combination of four previously described and four newly designed probes, approximately 80% of bacteria recovered from the murine large intestine and 71% of bacteria recovered from the murine caecum could be identified by fluorescence in situ hybridization (FISH).

  19. Library Standards: Evidence of Library Effectiveness and Accreditation.

    Science.gov (United States)

    Ebbinghouse, Carol

    1999-01-01

    Discusses accreditation standards for libraries based on experiences in an academic law library. Highlights include the accreditation process; the impact of distance education and remote technologies on accreditation; and a list of Internet sources of standards and information. (LRW)

  20. Computational redesign of bacterial biotin carboxylase inhibitors using structure-based virtual screening of combinatorial libraries.

    Science.gov (United States)

    Brylinski, Michal; Waldrop, Grover L

    2014-04-02

    As the spread of antibiotic resistant bacteria steadily increases, there is an urgent need for new antibacterial agents. Because fatty acid synthesis is only used for membrane biogenesis in bacteria, the enzymes in this pathway are attractive targets for antibacterial agent development. Acetyl-CoA carboxylase catalyzes the committed and regulated step in fatty acid synthesis. In bacteria, the enzyme is composed of three distinct protein components: biotin carboxylase, biotin carboxyl carrier protein, and carboxyltransferase. Fragment-based screening revealed that amino-oxazole inhibits biotin carboxylase activity and also exhibits antibacterial activity against Gram-negative organisms. In this report, we redesigned previously identified lead inhibitors to expand the spectrum of bacteria sensitive to the amino-oxazole derivatives by including Gram-positive species. Using 9,411 small organic building blocks, we constructed a diverse combinatorial library of 1.2×10⁸ amino-oxazole derivatives. A subset of 9×10⁶ of these compounds were subjected to structure-based virtual screening against seven biotin carboxylase isoforms using similarity-based docking by eSimDock. Potentially broad-spectrum antibiotic candidates were selected based on the consensus ranking by several scoring functions including non-linear statistical models implemented in eSimDock and traditional molecular mechanics force fields. The analysis of binding poses of the top-ranked compounds docked to biotin carboxylase isoforms suggests that: (1) binding of the amino-oxazole anchor is stabilized by a network of hydrogen bonds to residues 201, 202 and 204; (2) halogenated aromatic moieties attached to the amino-oxazole scaffold enhance interactions with a hydrophobic pocket formed by residues 157, 169, 171 and 203; and (3) larger substituents reach deeper into the binding pocket to form additional hydrogen bonds with the side chains of residues 209 and 233. These structural insights into drug

  1. WIMS-D library update

    International Nuclear Information System (INIS)

    2007-05-01

    WIMS-D (Winfrith Improved Multigroup Scheme-D) is the name of a family of software packages for reactor lattice calculations and is one of the few reactor lattice codes in the public domain and available on noncommercial terms. WIMSD-5B has recently been released from the OECD Nuclear Energy Agency Data Bank, and features major improvements in machine portability, as well as incorporating a few minor corrections. This version supersedes WIMS-D/4, which was released by the Winfrith Technology Centre in the United Kingdom for IBM machines and has been adapted for various other computer platforms in different laboratories. The main weakness of the WIMS-D package is the multigroup constants library, which is based on very old data. The relatively good performance of WIMS-D is attributed to a series of empirical adjustments to the multigroup data. However, the adjustments are not always justified on the basis of more accurate and recent experimental measurements. Following the release of new and revised evaluated nuclear data files, it was felt that the performance of WIMS-D could be improved by updating the associated library. The WIMS-D Library Update Project (WLUP) was initiated in the early 1990s with the support of the IAEA. This project consisted of voluntary contributions from a large number of participants. Several benchmarks for testing the library were identified and analysed, the WIMSR module of the NJOY code system was upgraded and the author of NJOY accepted the proposed updates for the official code system distribution. A detailed parametric study was performed to investigate the effects of various data processing input options on the integral results. In addition, the data processing methods for the main reactor materials were optimized. Several partially updated libraries were produced for testing purposes. The final stage of the WLUP was organized as a coordinated research project (CRP) in order to speed up completion of the fully updated library

  2. A statistical kinematic source inversion approach based on the QUESO library for uncertainty quantification and prediction

    Science.gov (United States)

    Zielke, Olaf; McDougall, Damon; Mai, Martin; Babuska, Ivo

    2014-05-01

    Seismic, often augmented with geodetic data, are frequently used to invert for the spatio-temporal evolution of slip along a rupture plane. The resulting images of the slip evolution for a single event, inferred by different research teams, often vary distinctly, depending on the adopted inversion approach and rupture model parameterization. This observation raises the question, which of the provided kinematic source inversion solutions is most reliable and most robust, and — more generally — how accurate are fault parameterization and solution predictions? These issues are not included in "standard" source inversion approaches. Here, we present a statistical inversion approach to constrain kinematic rupture parameters from teleseismic body waves. The approach is based a) on a forward-modeling scheme that computes synthetic (body-)waves for a given kinematic rupture model, and b) on the QUESO (Quantification of Uncertainty for Estimation, Simulation, and Optimization) library that uses MCMC algorithms and Bayes theorem for sample selection. We present Bayesian inversions for rupture parameters in synthetic earthquakes (i.e. for which the exact rupture history is known) in an attempt to identify the cross-over at which further model discretization (spatial and temporal resolution of the parameter space) is no longer attributed to a decreasing misfit. Identification of this cross-over is of importance as it reveals the resolution power of the studied data set (i.e. teleseismic body waves), enabling one to constrain kinematic earthquake rupture histories of real earthquakes at a resolution that is supported by data. In addition, the Bayesian approach allows for mapping complete posterior probability density functions of the desired kinematic source parameters, thus enabling us to rigorously assess the uncertainties in earthquake source inversions.

  3. Library Computing

    Science.gov (United States)

    Library Computing, 1985

    1985-01-01

    Special supplement to "Library Journal" and "School Library Journal" covers topics of interest to school, public, academic, and special libraries planning for automation: microcomputer use, readings in automation, online searching, databases of microcomputer software, public access to microcomputers, circulation, creating a…

  4. Waste Contaminants at Military Bases Working Group report

    International Nuclear Information System (INIS)

    1993-01-01

    The Waste Contaminants at Military Bases Working Group has screened six prospective demonstration projects for consideration by the Federal Advisory Committee to Develop On-Site Innovative Technologies (DOIT). These projects include the Kirtland Air Force Base Demonstration Project, the March Air Force Base Demonstration Project, the McClellan Air Force Base Demonstration Project, the Williams Air Force Base Demonstration Project, and two demonstration projects under the Air Force Center for Environmental Excellence. A seventh project (Port Hueneme Naval Construction Battalion Center) was added to list of prospective demonstrations after the September 1993 Working Group Meeting. This demonstration project has not been screened by the working group. Two additional Air Force remediation programs are also under consideration and are described in Section 6 of this document. The following information on prospective demonstrations was collected by the Waste Contaminants at Military Bases Working Group to assist the DOIT Committee in making Phase 1 Demonstration Project recommendations. The remainder of this report is organized into seven sections: Work Group Charter's mission and vision; contamination problems, current technology limitations, and institutional and regulatory barriers to technology development and commercialization, and work force issues; screening process for initial Phase 1 demonstration technologies and sites; demonstration descriptions -- good matches;demonstration descriptions -- close matches; additional candidate demonstration projects; and next steps

  5. Measuring Levels of Work in Academic Libraries: A Time Based Approach.

    Science.gov (United States)

    Gould, Donald P.

    1985-01-01

    Using Stratified Systems Theory, which focuses on the manager-subordinate relationship in the bureaucratic structure, a study was conducted to measure level of responsibility in work of 37 professional and nonprofessional positions in four academic library technical services departments. Three levels of work were measured in "time-spans of…

  6. EcoIS: An image serialization library for plot-based plant flowering phenology

    DEFF Research Database (Denmark)

    Granados, Joel A.; Bonnet, Philippe; Hansen, Lars Hostrup

    2013-01-01

    they are produced by introducing an open source Python (www.python.org) library called EcoIS that creates image series from unaligned pictures of specially equipped plots. We use EcoIS to sample flowering phenology plots in a high arctic environment and create image series that later generate phenophase counts...

  7. The design of a web – based integrated library system with internet ...

    African Journals Online (AJOL)

    Developing countries like Nigeria face series of defects in developing, managing and securing an Integrated Library System (ILS) in tertiary institutions and Secondary Schools where they are mostly needed. ILSs face issues such as non – interactive, speed, cost, unavailability of experienced users and programmers and ...

  8. ANSL-V: ENDF/B-V based multigroup cross-section libraries for Advanced Neutron Source (ANS) reactor studies. Supplement 1

    Energy Technology Data Exchange (ETDEWEB)

    Wright, R.Q.; Renier, J.P.; Bucholz, J.A.

    1995-08-01

    The original ANSL-V cross-section libraries (ORNL-6618) were developed over a period of several years for the physics analysis of the ANS reactor, with little thought toward including the materials commonly needed for shielding applications. Materials commonly used for shielding applications include calcium barium, sulfur, phosphorous, and bismuth. These materials, as well as {sup 6}Li, {sup 7}Li, and the naturally occurring isotopes of hafnium, have been added to the ANSL-V libraries. The gamma-ray production and gamma-ray interaction cross sections were completely regenerated for the ANSL-V 99n/44g library which did not exist previously. The MALOCS module was used to collapse the 99n/44g coupled library to the 39n/44g broad- group library. COMET was used to renormalize the two-dimensional (2- D) neutron matrix sums to agree with the one-dimensional (1-D) averaged values. The FRESH module was used to adjust the thermal scattering matrices on the 99n/44g and 39n/44g ANSL-V libraries. PERFUME was used to correct the original XLACS Legendre polynomial fits to produce acceptable distributions. The final ANSL-V 99n/44g and 39n/44g cross-section libraries were both checked by running RADE. The AIM module was used to convert the master cross-section libraries from binary coded decimal to binary format (or vice versa).

  9. FRDS.Broker Library

    DEFF Research Database (Denmark)

    2018-01-01

    The FRDS.Broker library is a teaching oriented implementation of the Broker architectural pattern for distributed remote method invocation. It defines the central roles of the pattern and provides implementations of those roles that are not domain/use case specific. It provides a JSON based (GSon...... library) Requestor implementation, and implementations of the ClientRequestHandler and ServerRequestHandler roles in both a Java socket based and a Http/URI tunneling based variants. The latter us based upon the UniRest and Spark-Java libraries. The Broker pattern and the source code is explained...

  10. Health sciences libraries' subscriptions to journals: expectations of general practice departments and collection-based analysis.

    Science.gov (United States)

    Barreau, David; Bouton, Céline; Renard, Vincent; Fournier, Jean-Pascal

    2018-04-01

    The aims of this study were to (i) assess the expectations of general practice departments regarding health sciences libraries' subscriptions to journals and (ii) describe the current general practice journal collections of health sciences libraries. A cross-sectional survey was distributed electronically to the thirty-five university general practice departments in France. General practice departments were asked to list ten journals to which they expected access via the subscriptions of their health sciences libraries. A ranked reference list of journals was then developed. Access to these journals was assessed through a survey sent to all health sciences libraries in France. Adequacy ratios (access/need) were calculated for each journal. All general practice departments completed the survey. The total reference list included 44 journals. This list was heterogeneous in terms of indexation/impact factor, language of publication, and scope (e.g., patient care, research, or medical education). Among the first 10 journals listed, La Revue Prescrire (96.6%), La Revue du Praticien-Médecine Générale (90.9%), the British Medical Journal (85.0%), Pédagogie Médicale (70.0%), Exercer (69.7%), and the Cochrane Database of Systematic Reviews (62.5%) had the highest adequacy ratios, whereas Family Practice (4.2%), the British Journal of General Practice (16.7%), Médecine (29.4%), and the European Journal of General Practice (33.3%) had the lowest adequacy ratios. General practice departments have heterogeneous expectations in terms of health sciences libraries' subscriptions to journals. It is important for librarians to understand the heterogeneity of these expectations, as well as local priorities, so that journal access meets users' needs.

  11. Group Membership, Group Change, and Intergroup Attitudes: A Recategorization Model Based on Cognitive Consistency Principles

    Science.gov (United States)

    Roth, Jenny; Steffens, Melanie C.; Vignoles, Vivian L.

    2018-01-01

    The present article introduces a model based on cognitive consistency principles to predict how new identities become integrated into the self-concept, with consequences for intergroup attitudes. The model specifies four concepts (self-concept, stereotypes, identification, and group compatibility) as associative connections. The model builds on two cognitive principles, balance–congruity and imbalance–dissonance, to predict identification with social groups that people currently belong to, belonged to in the past, or newly belong to. More precisely, the model suggests that the relative strength of self-group associations (i.e., identification) depends in part on the (in)compatibility of the different social groups. Combining insights into cognitive representation of knowledge, intergroup bias, and explicit/implicit attitude change, we further derive predictions for intergroup attitudes. We suggest that intergroup attitudes alter depending on the relative associative strength between the social groups and the self, which in turn is determined by the (in)compatibility between social groups. This model unifies existing models on the integration of social identities into the self-concept by suggesting that basic cognitive mechanisms play an important role in facilitating or hindering identity integration and thus contribute to reducing or increasing intergroup bias. PMID:29681878

  12. Group Membership, Group Change, and Intergroup Attitudes: A Recategorization Model Based on Cognitive Consistency Principles

    Directory of Open Access Journals (Sweden)

    Jenny Roth

    2018-04-01

    Full Text Available The present article introduces a model based on cognitive consistency principles to predict how new identities become integrated into the self-concept, with consequences for intergroup attitudes. The model specifies four concepts (self-concept, stereotypes, identification, and group compatibility as associative connections. The model builds on two cognitive principles, balance–congruity and imbalance–dissonance, to predict identification with social groups that people currently belong to, belonged to in the past, or newly belong to. More precisely, the model suggests that the relative strength of self-group associations (i.e., identification depends in part on the (incompatibility of the different social groups. Combining insights into cognitive representation of knowledge, intergroup bias, and explicit/implicit attitude change, we further derive predictions for intergroup attitudes. We suggest that intergroup attitudes alter depending on the relative associative strength between the social groups and the self, which in turn is determined by the (incompatibility between social groups. This model unifies existing models on the integration of social identities into the self-concept by suggesting that basic cognitive mechanisms play an important role in facilitating or hindering identity integration and thus contribute to reducing or increasing intergroup bias.

  13. Group Membership, Group Change, and Intergroup Attitudes: A Recategorization Model Based on Cognitive Consistency Principles.

    Science.gov (United States)

    Roth, Jenny; Steffens, Melanie C; Vignoles, Vivian L

    2018-01-01

    The present article introduces a model based on cognitive consistency principles to predict how new identities become integrated into the self-concept, with consequences for intergroup attitudes. The model specifies four concepts (self-concept, stereotypes, identification, and group compatibility) as associative connections. The model builds on two cognitive principles, balance-congruity and imbalance-dissonance, to predict identification with social groups that people currently belong to, belonged to in the past, or newly belong to. More precisely, the model suggests that the relative strength of self-group associations (i.e., identification) depends in part on the (in)compatibility of the different social groups. Combining insights into cognitive representation of knowledge, intergroup bias, and explicit/implicit attitude change, we further derive predictions for intergroup attitudes. We suggest that intergroup attitudes alter depending on the relative associative strength between the social groups and the self, which in turn is determined by the (in)compatibility between social groups. This model unifies existing models on the integration of social identities into the self-concept by suggesting that basic cognitive mechanisms play an important role in facilitating or hindering identity integration and thus contribute to reducing or increasing intergroup bias.

  14. Learners’ views about cloud computing-based group activities

    Directory of Open Access Journals (Sweden)

    Yildirim Serkan

    2017-01-01

    Full Text Available Thanks to its use independently of time and place during the process of software development and by making it easier to access to information with mobile technologies, cloud based environments attracted the attention of education world and this technology started to be used in various activities. In this study, for programming education, the effects of extracurricular group assignments in cloud based environments on learners were evaluated in terms of group work satisfaction, ease of use and user satisfaction. Within the scope of computer programming education lasting eight weeks, a total of 100 students participated in the study including 34 men and 66 women. Participants were divided into groups of at least three people considering the advantages of cooperative learning in programming education. In this study carried out in both conventional and cloud based environments, between groups factorial design was used as research design. The data collected by questionnaires of opinions of group work were examined with quantitative analysis method. According to the study results extracurricular learning activities as group activity created satisfaction. However, perceptions of easy use of the environment and user satisfaction were partly positive. Despite the similar understandings; male participants were easier to perceive use of cloud computing based environments. Some variables such as class level, satisfaction, computer and internet usage time do not have any effect on satisfaction and perceptions of ease of use. Evening class students stated that they found it easy to use cloud based learning environments and became more satisfied with using these environments besides being happier with group work than daytime students.

  15. Quantum mechanical energy-based screening of combinatorially generated library of tautomers. TauTGen: a tautomer generator program.

    Science.gov (United States)

    Harańczyk, Maciej; Gutowski, Maciej

    2007-01-01

    We describe a procedure of finding low-energy tautomers of a molecule. The procedure consists of (i) combinatorial generation of a library of tautomers, (ii) screening based on the results of geometry optimization of initial structures performed at the density functional level of theory, and (iii) final refinement of geometry for the top hits at the second-order Möller-Plesset level of theory followed by single-point energy calculations at the coupled cluster level of theory with single, double, and perturbative triple excitations. The library of initial structures of various tautomers is generated with TauTGen, a tautomer generator program. The procedure proved to be successful for these molecular systems for which common chemical knowledge had not been sufficient to predict the most stable structures.

  16. pyOpenMS: a Python-based interface to the OpenMS mass-spectrometry algorithm library.

    Science.gov (United States)

    Röst, Hannes L; Schmitt, Uwe; Aebersold, Ruedi; Malmström, Lars

    2014-01-01

    pyOpenMS is an open-source, Python-based interface to the C++ OpenMS library, providing facile access to a feature-rich, open-source algorithm library for MS-based proteomics analysis. It contains Python bindings that allow raw access to the data structures and algorithms implemented in OpenMS, specifically those for file access (mzXML, mzML, TraML, mzIdentML among others), basic signal processing (smoothing, filtering, de-isotoping, and peak-picking) and complex data analysis (including label-free, SILAC, iTRAQ, and SWATH analysis tools). pyOpenMS thus allows fast prototyping and efficient workflow development in a fully interactive manner (using the interactive Python interpreter) and is also ideally suited for researchers not proficient in C++. In addition, our code to wrap a complex C++ library is completely open-source, allowing other projects to create similar bindings with ease. The pyOpenMS framework is freely available at https://pypi.python.org/pypi/pyopenms while the autowrap tool to create Cython code automatically is available at https://pypi.python.org/pypi/autowrap (both released under the 3-clause BSD licence). © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Learning based on library automation in mobile devices: The video production by students of Universidade Federal do Cariri Library Science Undergraduate Degree

    Directory of Open Access Journals (Sweden)

    David Vernon VIEIRA

    Full Text Available Abstract The video production for learning has been evident over the last few years especially when it involves aspects of the application of hardware and software for automation spaces. In Librarianship Undergraduate Degrees the need for practical learning focused on the knowledge of the requirements for library automation demand on teacher to develop an educational content to enable the student to learn through videos in order to increase the knowledge about information technology. Thus, discusses the possibilities of learning through mobile devices in education reporting an experience that took place with students who entered in March, 2015 (2015.1 Bachelor Degree in Library Science from the Universidade Federal do Cariri (Federal University of Cariri in state of Ceará, Brazil. The literature review includes articles publicated in scientific journals and conference proceedings and books in English, Portuguese and Spanish on the subject. The methodology with quantitative and qualitative approach includes an exploratory study, where the data collection was used online survey to find out the experience of the elaboration of library automation videos by students who studied in that course. The learning experience using mobile devices for recording of technological environments of libraries allowed them to be produced 25 videos that contemplated aspects of library automation having these actively participated in production of the video and its publication on the Internet.

  18. Testing of a JEF-1 based WIMS-D cross section library for migration area and k-infinity predictions for LWHCR lattices

    International Nuclear Information System (INIS)

    Pelloni, S.; Stepanek, J.

    1987-01-01

    The cell code WIMSD4 is used for the analysis of PROTEUS-LWHCR experiments. A library for this code which is based on the European evaluation JEF-1 was produced at EIR using the Los Alamos NJOY system with its module WIMSR and the Canadian management code WILMA. In general, this library delivered more accurate eigenvalues and reaction rates than the WIMS-Standard and WIMS81 libraries did in comparison to experimental values from PROTEUS-LWHCR Cores 1-3. However, large discrepancies (up to about 10%) occured between calculated migration areas (M 2 ). Additional investigations have been undertaken to clarify this problem, since theoretical M 2 -values are needed for deducing k-infinity in the experiments. This has been done in the context of calculations for a reference LWHCR test lattice. The following major reasons for these deviations were found. First, the self-scattering term in non-moderators (P 0 matrix) in the JEF-1 library was not transport corrected. Second, Standard and JEF-1 libraries use infinite dilute cross sections for 238 U, whereas the WIMS81 library uses fully shielded cross sections. Third, the standard library uses the 'row' formula for the transport correction, whereas the 'inflow' formula is applied in the case of JEF-1 and WIMS81 libraries. Lastly, oxygen and 238 U scattering cross sections in the fast energy range are smaller in the case of the WIMS81 library. Differences in calculated k-infinity values between the currently used library and WIMS81 (up to 3%) come (in order of importance for the reference LWHCR lattice) mainly from resonance cross sections for 240 Pu capture, 238 U capture and 239 Pu fission. Recommendations have been made for generating a new JEF-1 library using updated versions of WIMSR and WILMA. (author)

  19. Tapping Teen Talent in Queens: A Library-Based, LSCA-Funded Youth Development Success Story from New York.

    Science.gov (United States)

    Williams, Barbara Osborne

    1996-01-01

    Describes a program developed by the Youth Services Division at the Queens Borough Public Library's Central Library to help teenagers maximize growth opportunities, build self-esteem, and see the library as a life resource. Highlights include securing funding through LSCA (Library Services and Construction Act), recruiting participants, and…

  20. A framework for grouping nanoparticles based on their measurable characteristics.

    Science.gov (United States)

    Sayes, Christie M; Smith, P Alex; Ivanov, Ivan V

    2013-01-01

    There is a need to take a broader look at nanotoxicological studies. Eventually, the field will demand that some generalizations be made. To begin to address this issue, we posed a question: are metal colloids on the nanometer-size scale a homogeneous group? In general, most people can agree that the physicochemical properties of nanomaterials can be linked and related to their induced toxicological responses. The focus of this study was to determine how a set of selected physicochemical properties of five specific metal-based colloidal materials on the nanometer-size scale - silver, copper, nickel, iron, and zinc - could be used as nanodescriptors that facilitate the grouping of these metal-based colloids. The example of the framework pipeline processing provided in this paper shows the utility of specific statistical and pattern recognition techniques in grouping nanoparticles based on experimental data about their physicochemical properties. Interestingly, the results of the analyses suggest that a seemingly homogeneous group of nanoparticles could be separated into sub-groups depending on interdependencies observed in their nanodescriptors. These particles represent an important category of nanomaterials that are currently mass produced. Each has been reputed to induce toxicological and/or cytotoxicological effects. Here, we propose an experimental methodology coupled with mathematical and statistical modeling that can serve as a prototype for a rigorous framework that aids in the ability to group nanomaterials together and to facilitate the subsequent analysis of trends in data based on quantitative modeling of nanoparticle-specific structure-activity relationships. The computational part of the proposed framework is rather general and can be applied to other groups of nanomaterials as well.

  1. Diagnosis related group grouping study of senile cataract patients based on E-CHAID algorithm

    Science.gov (United States)

    Luo, Ai-Jing; Chang, Wei-Fu; Xin, Zi-Rui; Ling, Hao; Li, Jun-Jie; Dai, Ping-Ping; Deng, Xuan-Tong; Zhang, Lei; Li, Shao-Gang

    2018-01-01

    AIM To figure out the contributed factors of the hospitalization expenses of senile cataract patients (HECP) and build up an area-specified senile cataract diagnosis related group (DRG) of Shanghai thereby formulating the reference range of HECP and providing scientific basis for the fair use and supervision of the health care insurance fund. METHODS The data was collected from the first page of the medical records of 22 097 hospitalized patients from tertiary hospitals in Shanghai from 2010 to 2012 whose major diagnosis were senile cataract. Firstly, we analyzed the influence factors of HECP using univariate and multivariate analysis. DRG grouping was conducted according to the exhaustive Chi-squared automatic interaction detector (E-CHAID) model, using HECP as target variable. Finally we evaluated the grouping results using non-parametric test such as Kruskal-Wallis H test, RIV, CV, etc. RESULTS The 6 DRGs were established as well as criterion of HECP, using age, sex, type of surgery and whether complications/comorbidities occurred as the key variables of classification node of senile cataract cases. CONCLUSION The grouping of senile cataract cases based on E-CHAID algorithm is reasonable. And the criterion of HECP based on DRG can provide a feasible way of management in the fair use and supervision of medical insurance fund. PMID:29487824

  2. Diagnosis related group grouping study of senile cataract patients based on E-CHAID algorithm.

    Science.gov (United States)

    Luo, Ai-Jing; Chang, Wei-Fu; Xin, Zi-Rui; Ling, Hao; Li, Jun-Jie; Dai, Ping-Ping; Deng, Xuan-Tong; Zhang, Lei; Li, Shao-Gang

    2018-01-01

    To figure out the contributed factors of the hospitalization expenses of senile cataract patients (HECP) and build up an area-specified senile cataract diagnosis related group (DRG) of Shanghai thereby formulating the reference range of HECP and providing scientific basis for the fair use and supervision of the health care insurance fund. The data was collected from the first page of the medical records of 22 097 hospitalized patients from tertiary hospitals in Shanghai from 2010 to 2012 whose major diagnosis were senile cataract. Firstly, we analyzed the influence factors of HECP using univariate and multivariate analysis. DRG grouping was conducted according to the exhaustive Chi-squared automatic interaction detector (E-CHAID) model, using HECP as target variable. Finally we evaluated the grouping results using non-parametric test such as Kruskal-Wallis H test, RIV, CV, etc. The 6 DRGs were established as well as criterion of HECP, using age, sex, type of surgery and whether complications/comorbidities occurred as the key variables of classification node of senile cataract cases. The grouping of senile cataract cases based on E-CHAID algorithm is reasonable. And the criterion of HECP based on DRG can provide a feasible way of management in the fair use and supervision of medical insurance fund.

  3. Diagnosis related group grouping study of senile cataract patients based on E-CHAID algorithm

    Directory of Open Access Journals (Sweden)

    Ai-Jing Luo

    2018-02-01

    Full Text Available AIM: To figure out the contributed factors of the hospitalization expenses of senile cataract patients (HECP and build up an area-specified senile cataract diagnosis related group (DRG of Shanghai thereby formulating the reference range of HECP and providing scientific basis for the fair use and supervision of the health care insurance fund. METHODS: The data was collected from the first page of the medical records of 22 097 hospitalized patients from tertiary hospitals in Shanghai from 2010 to 2012 whose major diagnosis were senile cataract. Firstly, we analyzed the influence factors of HECP using univariate and multivariate analysis. DRG grouping was conducted according to the exhaustive Chi-squared automatic interaction detector (E-CHAID model, using HECP as target variable. Finally we evaluated the grouping results using non-parametric test such as Kruskal-Wallis H test, RIV, CV, etc. RESULTS: The 6 DRGs were established as well as criterion of HECP, using age, sex, type of surgery and whether complications/comorbidities occurred as the key variables of classification node of senile cataract cases. CONCLUSION: The grouping of senile cataract cases based on E-CHAID algorithm is reasonable. And the criterion of HECP based on DRG can provide a feasible way of management in the fair use and supervision of medical insurance fund.

  4. Developing European Library Services in Changing Times

    Directory of Open Access Journals (Sweden)

    Paul Ayris

    2012-01-01

    Full Text Available The purpose of this article is to explain what academic and national libraries can do to continue to offer services and facilities at a time of economic difficulties. It identifies a number of methodologies and opportunities that are open to libraries and takes the view that it is never wise to waste a good crisis, because all threats are really opportunities in disguise. The article looks at the initial economic context for European research libraries and then examines ways in which libraries can tackle the threats which the current financial crisis poses. Joint procurement is one way in which libraries can achieve value for money, and the paper examines the role of JIS C Collections in the UK. Innovation through collaboration and shared services are also ways in which libraries can innovate/make savings in a cost-effective way by sharing the burden of costs around the partnership. The paper gives two examples: one which is now well established, the DART-Europe portal for Open Access e-theses; and one which is in the early stages of being discussed — a cloud-based solution for true collaborative cataloguing amongst the UK’s research and national libraries. The European Research Area (ERA and the contributions that libraries can make to this infrastructure through innovative EU project funding are analysed in some detail by looking at LI BER’s EU project portfolio. Finally, change and growth can come through changes to legal frameworks, and the paper looks at the Hargreaves review of copyright frameworks in the UK and the launch of the new library-based EU lobbying group for copyright reform, Information Sans Frontières (IS F.

  5. The impact of computerisation of library operations on library ...

    African Journals Online (AJOL)

    The use of computer-based systems in libraries and information units is now a vogue. The era of manual system in library operations is on its way to extinction. Recent developments in information world tend towards a globalized information communication technology (ICT). The library as a dynamic institution cannot afford ...

  6. SOA-based digital library services and composition in biomedical applications.

    Science.gov (United States)

    Zhao, Xia; Liu, Enjie; Clapworthy, Gordon J; Viceconti, Marco; Testi, Debora

    2012-06-01

    Carefully collected, high-quality data are crucial in biomedical visualization, and it is important that the user community has ready access to both this data and the high-performance computing resources needed by the complex, computational algorithms that will process it. Biological researchers generally require data, tools and algorithms from multiple providers to achieve their goals. This paper illustrates our response to the problems that result from this. The Living Human Digital Library (LHDL) project presented in this paper has taken advantage of Web Services to build a biomedical digital library infrastructure that allows clinicians and researchers not only to preserve, trace and share data resources, but also to collaborate at the data-processing level. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  7. IoT-Based Library Automation and Monitoring system: Developing an Implementation framework of Implementation

    OpenAIRE

    Bayani, Majid; Segura, Alberto; Alvarado, Marjorie; Loaiza, Mayra

    2018-01-01

    Currently, the Information and Communication Technology (ICT) and related topics such as Internet of Things (IoT) have an essential influence on all elements of human life. IoT as a prevalent phenomenon is transforming daily life by the usage of the smart features of Radio Frequency Identification (RFID) and Wireless Sensor Network (WSN) technologies. As IoT progresses, it has extended in size and dimension, improving many contexts of the society; such as, the traditional library system. This...

  8. Cleaners' experiences with group-based workplace physical training

    DEFF Research Database (Denmark)

    Kirkelund, Lasse; Mortensen, Ole Steen; Holtermann, Andreas

    2012-01-01

    This study investigates how work-site health promotion intervention, by involving group-based physical coordination training, may increase participants’ social awareness of new ways to use the body. Purpose: We investigated cleaners’ experiences with a one-year health promotion intervention...... involving group-based physical coordination training (PCT) during working hours. Design: We conducted a qualitative evaluation using method triangulation; continuous unfocused participant observation during the whole intervention, semi-structured focus group interview, and individual written evaluations one...... for implementation seem to be important for sustained effects of health-promotion interventions in the workplace. Originality: The social character of the physical training facilitated a community of practice, which potentially supported the learning of new competencies, and how to improve the organization...

  9. Classification and Target Group Selection Based Upon Frequent Patterns

    NARCIS (Netherlands)

    W.H.L.M. Pijls (Wim); R. Potharst (Rob)

    2000-01-01

    textabstractIn this technical report , two new algorithms based upon frequent patterns are proposed. One algorithm is a classification method. The other one is an algorithm for target group selection. In both algorithms, first of all, the collection of frequent patterns in the training set is

  10. New unified field theory based on the conformal group

    Energy Technology Data Exchange (ETDEWEB)

    Pessa, E [Rome Univ. (Italy). Ist. di Matematica

    1980-10-01

    Based on a six-dimensional generalization of Maxwell's equations, a new unified theory of the electromagnetic and gravitational field is developed. Additional space-time coordinates are interpreted only as mathematical tools in order to obtain a linear realization of the four-dimensional conformal group.

  11. Emotional Regulation: Considerations for School-Based Group Interventions

    Science.gov (United States)

    Augustyniak, Kristine M.; Brooks, Morgan; Rinaldo, Vincent J.; Bogner, Roselind; Hodges, Shannon

    2009-01-01

    School-based professionals have entered the 21st century with a heightened call to address the emotional and behavioral concerns of youth. While cognitive-behavioral therapies and psychoeducational groups have demonstrated moderate effects with children and adolescents, there is little available research to assist clinicians in refining treatments…

  12. Fullerene-based Anchoring Groups for Molecular Electronics

    DEFF Research Database (Denmark)

    Martin, Christian A.; Ding, Dapeng; Sørensen, Jakob Kryger

    2008-01-01

    We present results on a new fullerene-based anchoring group for molecular electronics. Using lithographic mechanically controllable break junctions in vacuum we have determined the conductance and stability of single-molecule junctions of 1,4-bis(fullero[c]pyrrolidin-1-yl)benzene. The compound can...

  13. WWW-based environments for collaborative group work

    NARCIS (Netherlands)

    Collis, Betty

    1998-01-01

    Since 1994, we have been involved in the design and use of a series of WWW-based environments to support collaborative group work for students in a technical university in The Netherlands. These environments, and the course re-design that accompanies each new environment, began in April 1994 and

  14. Problem-Based Group Activities for Teaching Sensation and Perception

    Science.gov (United States)

    Kreiner, David S.

    2009-01-01

    This article describes 14 problem-based group activities for a sensation and perception course. The intent was to provide opportunities for students to practice applying their knowledge to real-world problems related to course content. Student ratings of how effectively the activities helped them learn were variable but relatively high. Students…

  15. Intracellular directed evolution of proteins from combinatorial libraries based on conditional phage replication.

    Science.gov (United States)

    Brödel, Andreas K; Jaramillo, Alfonso; Isalan, Mark

    2017-09-01

    Directed evolution is a powerful tool to improve the characteristics of biomolecules. Here we present a protocol for the intracellular evolution of proteins with distinct differences and advantages in comparison with established techniques. These include the ability to select for a particular function from a library of protein variants inside cells, minimizing undesired coevolution and propagation of nonfunctional library members, as well as allowing positive and negative selection logics using basally active promoters. A typical evolution experiment comprises the following stages: (i) preparation of a combinatorial M13 phagemid (PM) library expressing variants of the gene of interest (GOI) and preparation of the Escherichia coli host cells; (ii) multiple rounds of an intracellular selection process toward a desired activity; and (iii) the characterization of the evolved target proteins. The system has been developed for the selection of new orthogonal transcription factors (TFs) but is capable of evolving any gene-or gene circuit function-that can be linked to conditional M13 phage replication. Here we demonstrate our approach using as an example the directed evolution of the bacteriophage λ cI TF against two synthetic bidirectional promoters. The evolved TF variants enable simultaneous activation and repression against their engineered promoters and do not cross-react with the wild-type promoter, thus ensuring orthogonality. This protocol requires no special equipment, allowing synthetic biologists and general users to evolve improved biomolecules within ∼7 weeks.

  16. Assessment of statistical methods used in library-based approaches to microbial source tracking.

    Science.gov (United States)

    Ritter, Kerry J; Carruthers, Ethan; Carson, C Andrew; Ellender, R D; Harwood, Valerie J; Kingsley, Kyle; Nakatsu, Cindy; Sadowsky, Michael; Shear, Brian; West, Brian; Whitlock, John E; Wiggins, Bruce A; Wilbur, Jayson D

    2003-12-01

    Several commonly used statistical methods for fingerprint identification in microbial source tracking (MST) were examined to assess the effectiveness of pattern-matching algorithms to correctly identify sources. Although numerous statistical methods have been employed for source identification, no widespread consensus exists as to which is most appropriate. A large-scale comparison of several MST methods, using identical fecal sources, presented a unique opportunity to assess the utility of several popular statistical methods. These included discriminant analysis, nearest neighbour analysis, maximum similarity and average similarity, along with several measures of distance or similarity. Threshold criteria for excluding uncertain or poorly matched isolates from final analysis were also examined for their ability to reduce false positives and increase prediction success. Six independent libraries used in the study were constructed from indicator bacteria isolated from fecal materials of humans, seagulls, cows and dogs. Three of these libraries were constructed using the rep-PCR technique and three relied on antibiotic resistance analysis (ARA). Five of the libraries were constructed using Escherichia coli and one using Enterococcus spp. (ARA). Overall, the outcome of this study suggests a high degree of variability across statistical methods. Despite large differences in correct classification rates among the statistical methods, no single statistical approach emerged as superior. Thresholds failed to consistently increase rates of correct classification and improvement was often associated with substantial effective sample size reduction. Recommendations are provided to aid in selecting appropriate analyses for these types of data.

  17. Natural product-like virtual libraries: recursive atom-based enumeration.

    Science.gov (United States)

    Yu, Melvin J

    2011-03-28

    A new molecular enumerator is described that allows chemically and architecturally diverse sets of natural product-like and drug-like structures to be generated from a core structure as simple as a single carbon atom or as complex as a polycyclic ring system. Integrated with a rudimentary machine-learning algorithm, the enumerator has the ability to assemble biased virtual libraries enriched in compounds predicted to meet target criteria. The ability to dynamically generate relatively small focused libraries in a recursive manner could reduce the computational time and infrastructure necessary to construct and manage extremely large static libraries. Depending on enumeration conditions, natural product-like structures can be produced with a wide range of heterocyclic and alicyclic ring assemblies. Because natural products represent a proven source of validated structures for identifying and designing new drug candidates, mimicking the structural and topological diversity found in nature with a dynamic set of virtual natural product-like compounds may facilitate the creation of new ideas for novel, biologically relevant lead structures in areas of uncharted chemical space.

  18. Designing a diverse high-quality library for crystallography-based FBDD screening.

    Science.gov (United States)

    Tounge, Brett A; Parker, Michael H

    2011-01-01

    A well-chosen set of fragments is able to cover a large chemical space using a small number of compounds. The actual size and makeup of the fragment set is dependent on the screening method since each technique has its own practical limits in terms of the number of compounds that can be screened and requirements for compound solubility. In this chapter, an overview of the general requirements for a fragment library is presented for different screening platforms. In the case of the FBDD work at Johnson & Johnson Pharmaceutical Research and Development, L.L.C., our main screening technology is X-ray crystallography. Since every soaked protein crystal needs to be diffracted and a protein structure determined to delineate if a fragment binds, the size of our initial screening library cannot be a rate-limiting factor. For this reason, we have chosen 900 as the appropriate primary fragment library size. To choose the best set, we have developed our own mix of simple property ("Rule of 3") and "bad" substructure filtering. While this gets one a long way in terms of limiting the fragment pool, there are still tens of thousands of compounds to choose from after this initial step. Many of the choices left at this stage are not drug-like, so we have developed an FBDD Score to help select a 900-compound set. The details of this score and the filtering are presented. Copyright © 2011 Elsevier Inc. All rights reserved.

  19. Comparison of several chemometric methods of libraries and classifiers for the analysis of expired drugs based on Raman spectra.

    Science.gov (United States)

    Gao, Qun; Liu, Yan; Li, Hao; Chen, Hui; Chai, Yifeng; Lu, Feng

    2014-06-01

    Some expired drugs are difficult to detect by conventional means. If they are repackaged and sold back into market, they will constitute a new public health challenge. For the detection of repackaged expired drugs within specification, paracetamol tablet from a manufacturer was used as a model drug in this study for comparison of Raman spectra-based library verification and classification methods. Raman spectra of different batches of paracetamol tablets were collected and a library including standard spectra of unexpired batches of tablets was established. The Raman spectrum of each sample was identified by cosine and correlation with the standard spectrum. The average HQI of the suspicious samples and the standard spectrum were calculated. The optimum threshold values were 0.997 and 0.998 respectively as a result of ROC and four evaluations, for which the accuracy was up to 97%. Three supervised classifiers, PLS-DA, SVM and k-NN, were chosen to establish two-class classification models and compared subsequently. They were used to establish a classification of expired batches and an unexpired batch, and predict the suspect samples. The average accuracy was 90.12%, 96.80% and 89.37% respectively. Different pre-processing techniques were tried to find that first derivative was optimal for methods of libraries and max-min normalization was optimal for that of classifiers. The results obtained from these studies indicated both libraries and classifier methods could detect the expired drugs effectively, and they should be used complementarily in the fast-screening. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Students lead the library the importance of student contributions to the academic library

    CERN Document Server

    Arnold-Garza, Sara

    2017-01-01

    In six parts-Students as Employees, Students as Curators, Students as Ambassadors, the Library as Client, Student Groups as Library Leaders, and Students as Library Designers-Students Lead the Library provides case studies of programs and initiatives that seek student input, assistance, and leadership in the academic library. Through the library, students can develop leadership skills, cultivate high levels of engagement, and offer peer learning opportunities. Through the students, libraries can create participatory design processes, enhancement and transformation of the library's core functions, and expressed library value for stakeholders.

  1. Relationship marketing in a hospital library.

    Science.gov (United States)

    Enyeart, Amanda L; Weaver, Debbie

    2005-01-01

    This article explores relationship marketing as adopted by staff of the Forbes Medical Library at The Children's Hospital in Denver. It provides a broad overview of relationship marketing along with its applications in libraries, and a description of how the library staff has used specific relationships with different hospital groups to enhance library service. The examples illustrate the importance of persistence, patience, and flexibility when consciously developing relationships between a library and individuals or groups.

  2. Customer Satisfaction with Public Libraries.

    Science.gov (United States)

    D'Elia, George; Rodger, Eleanor Jo

    1996-01-01

    Surveys conducted in 142 urban public libraries examined customer satisfaction, comparisons with other libraries, and factors affecting satisfaction. Overall, customers were satisfied with their libraries but experienced different levels of satisfaction based on convenience, availability of materials and information, and services facilitating…

  3. Promotion: Study of the Library of the department of library and information science and book

    Directory of Open Access Journals (Sweden)

    Andreja Nagode

    2003-01-01

    Full Text Available The contribution presents basic information about academic libraries and their promotion. Librarians should have promotion knowledge since they have to promote and market their libraries. The paper presents the definition of academic libraries, their purpose, objectives and goals. Marketing and promotion in academic libraries are defined. The history of academic libraries and their promotion are described. The contribution presents results and the interpretation of the research, based on the study of users of the Library of the Department of Library and Information Science and Book studies. A new promotion plan for libraries based on the analysis of the academic library environment is introduced.

  4. Welcome to the National Wetlands Research Center Library: Not Just Another Library-A Special Library

    Science.gov (United States)

    Broussard, Linda

    2007-01-01

    Libraries are grouped into four major types: public, school, academic, and special. The U.S. Geological Survey's (USGS) National Wetlands Research Center (NWRC) library is classified as a special library because it is sponsored by the Federal government, and the collections focus on a specific subject. The NWRC library is the only USGS library dedicated to wetland science. Library personnel offer expert research services to meet the informational needs of NWRC scientists, managers, and support personnel. The NWRC library participates in international cataloging and resource sharing, which allows libraries from throughout the world to borrow from its collections. This sharing facilitates the research of other governmental agencies, universities, and those interested in the study of wetlands.

  5. Analog Group Delay Equalizers Design Based on Evolutionary Algorithm

    Directory of Open Access Journals (Sweden)

    M. Laipert

    2006-04-01

    Full Text Available This paper deals with a design method of the analog all-pass filter designated for equalization of the group delay frequency response of the analog filter. This method is based on usage of evolutionary algorithm, the Differential Evolution algorithm in particular. We are able to design such equalizers to be obtained equal-ripple group delay frequency response in the pass-band of the low-pass filter. The procedure works automatically without an input estimation. The method is presented on solving practical examples.

  6. Integrated system for production of neutronics and photonics calculational constants. Volume XVI. Tabular and graphical presentation of 175 neutron group constants derived from the LLL evaluated neutron data library (ENDL)

    International Nuclear Information System (INIS)

    Plechaty, E.F.; Cullen, D.E.; Howerton, R.J.; Kimlinger, J.R.

    1975-01-01

    As of February 3, 1975, 175 neutron group constants had been derived from the Evaluated Nuclear Data Library (ENDL) at LLL. In this volume, tables and graphs of the constants are presented along with the conventions used in their preparation. (U.S.)

  7. The academic library network

    Directory of Open Access Journals (Sweden)

    Jacek Wojciechowski

    2012-01-01

    Full Text Available The efficiency of libraries, academic libraries in particular, necessitates organizational changes facilitating or even imposing co-operation. Any structure of any university has to have an integrated network of libraries, with an appropriate division of work, and one that is consolidated as much as it is possible into medium-size or large libraries. Within thus created network, a chance arises to centralize the main library processes based on appropriate procedures in the main library, highly specialized, more effective and therefore cheaper in operation, including a co-ordination of all more important endeavours and tasks. Hierarchically subordinated libraries can be thus more focused on performing their routine service, more and more frequently providing for the whole of the university, and being able to adjust to changeable requirements and demands of patrons and of new tasks resulting from the new model of the university operation. Another necessary change seems to be a universal implementation of an ov rall programme framework that would include all services in the university’s library networks.

  8. Unified accelerator libraries

    International Nuclear Information System (INIS)

    Malitsky, Nikolay; Talman, Richard

    1997-01-01

    A 'Universal Accelerator Libraries' (UAL) environment is described. Its purpose is to facilitate program modularity and inter-program and inter-process communication among heterogeneous programs. The goal ultimately is to facilitate model-based control of accelerators

  9. Additivity of Feature-based and Symmetry-based Grouping Effects in Multiple Object Tracking

    Directory of Open Access Journals (Sweden)

    Chundi eWang

    2016-05-01

    Full Text Available Multiple object tracking (MOT is an attentional process wherein people track several moving targets among several distractors. Symmetry, an important indicator of regularity, is a general spatial pattern observed in natural and artificial scenes. According to the laws of perceptual organization proposed by Gestalt psychologists, regularity is a principle of perceptual grouping, such as similarity and closure. A great deal of research reported that feature-based similarity grouping (e.g., grouping based on color, size, or shape among targets in MOT tasks can improve tracking performance. However, no additive feature-based grouping effects have been reported where the tracking objects had two or more features. Additive effect refers to a greater grouping effect produced by grouping based on multiple cues instead of one cue. Can spatial symmetry produce a similar grouping effect similar to that of feature similarity in MOT tasks? Are the grouping effects based on symmetry and feature similarity additive? This study includes four experiments to address these questions. The results of Experiments 1 and 2 demonstrated the automatic symmetry-based grouping effects. More importantly, an additive grouping effect of symmetry and feature similarity was observed in Experiments 3 and 4. Our findings indicate that symmetry can produce an enhanced grouping effect in MOT and facilitate the grouping effect based on color or shape similarity. The where and what pathways might have played an important role in the additive grouping effect.

  10. About the Library - Betty Petersen Memorial Library

    Science.gov (United States)

    branch library of the NOAA Central Library. The library serves the NOAA Science Center in Camp Springs , Maryland. History and Mission: Betty Petersen Memorial Library began as a reading room in the NOAA Science Science Center staff and advises the library on all aspects of the library program. Library Newsletters

  11. The Impact of Library Tutorials on the Information Literacy Skills of Occupational Therapy and Physical Therapy Students in an Evidence-Based Practice Course: A Rubric Assessment.

    Science.gov (United States)

    Schweikhard, April J; Hoberecht, Toni; Peterson, Alyssa; Randall, Ken

    2018-01-01

    This study measures how online library instructional tutorials implemented into an evidence-based practice course have impacted the information literacy skills of occupational and physical therapy graduate students. Through a rubric assessment of final course papers, this study compares differences in students' search strategies and cited sources pre- and post-implementation of the tutorials. The population includes 180 randomly selected graduate students from before and after the library tutorials were introduced into the course curriculum. Results indicate a statistically significant increase in components of students' searching skills and ability to find higher levels of evidence after completing the library tutorials.

  12. Construction of 1,3,4-Oxadiazole and 1,3,4-Thiadiazole Library with a High Level of Skeletal Diversity Based on Branching Diversity-Oriented Synthesis on Solid-Phase Supports.

    Science.gov (United States)

    Ha, Ji-Eun; Yang, Seung-Ju; Gong, Young-Dae

    2018-02-12

    An efficient solid-phase synthetic route for the construction of 1,3,4-oxadiazole and 1,3,4-thiadiazole libraries based on branching diversity-oriented synthesis (DOS) has been developed in this study. The core skeleton resins, 1,3,4-oxadiazole and 1,3,4-thiadiazole, were obtained through desulfurative and dehydrative cyclizations of thiosemicarbazide resin, respectively. Various functional groups have been introduced to the core skeleton resins, such as aryl, amine, amide, urea, thiourea, and an amino acid. Most of the libraries were purified by simple trituration without extraction or column chromatography after cleavage of the products from the solid-supported resin. As a result, we obtained high yields of pure 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives (total numbers = 128). Finally, we confirmed the drug-like properties of our library by calculation of physicochemical properties, displays of the skeletal diversities of the library in 3D-space, and occupation of a broad range of areas by their functional groups.

  13. An Interactive Computer-Based Circulation System for Northwestern University: The Library Puts It to Work

    Directory of Open Access Journals (Sweden)

    Velma Veneziano

    1972-06-01

    Full Text Available Northwestern University Library's on-line circulation system has resulted in dramatic changes in practices and procedures in the Circulation Services Section. After a hectic period of implementation, the staff soon began to adjust to the system. Over the past year and a half, they have devised ways to use the system to maximum advantage, so that manual and machine systems now mesh in close harmony. Freed from time-consuming clerical chores, the staff have been challenged to use their released time to best advantage, with the result that the "service" in "Circulation Services" is much closer to being a reality.

  14. Group-based Motion Detection for Energy-Efficient Localisation

    Directory of Open Access Journals (Sweden)

    Alban Cotillon

    2012-10-01

    Full Text Available Long-term outdoor localization remains challenging due to the high energy profiles of GPS modules. Duty cycling the GPS module combined with inertial sensors can improve energy consumption. However, inertial sensors that are kept active all the time can also drain mobile node batteries. This paper proposes duty cycling strategies for inertial sensors to maintain a target position accuracy and node lifetime. We present a method for duty cycling motion sensors according to features of movement events, and evaluate its energy and accuracy profile for an empirical data trace of cattle movement. We further introduce the concept of group-based duty cycling, where nodes that cluster together can share the burden of motion detection to reduce their duty cycles. Our evaluation shows that both variants of motion sensor duty cycling yield up to 78% improvement in overall node power consumption, and that the group-based method yields an additional 20% power reduction during periods of low mobility.

  15. A novel method for human age group classification based on

    Directory of Open Access Journals (Sweden)

    Anuradha Yarlagadda

    2015-10-01

    Full Text Available In the computer vision community, easy categorization of a person’s facial image into various age groups is often quite precise and is not pursued effectively. To address this problem, which is an important area of research, the present paper proposes an innovative method of age group classification system based on the Correlation Fractal Dimension of complex facial image. Wrinkles appear on the face with aging thereby changing the facial edges of the image. The proposed method is rotation and poses invariant. The present paper concentrates on developing an innovative technique that classifies facial images into four categories i.e. child image (0–15, young adult image (15–30, middle-aged adult image (31–50, and senior adult image (>50 based on correlation FD value of a facial edge image.

  16. Group Elevator Peak Scheduling Based on Robust Optimization Model

    Directory of Open Access Journals (Sweden)

    ZHANG, J.

    2013-08-01

    Full Text Available Scheduling of Elevator Group Control System (EGCS is a typical combinatorial optimization problem. Uncertain group scheduling under peak traffic flows has become a research focus and difficulty recently. RO (Robust Optimization method is a novel and effective way to deal with uncertain scheduling problem. In this paper, a peak scheduling method based on RO model for multi-elevator system is proposed. The method is immune to the uncertainty of peak traffic flows, optimal scheduling is realized without getting exact numbers of each calling floor's waiting passengers. Specifically, energy-saving oriented multi-objective scheduling price is proposed, RO uncertain peak scheduling model is built to minimize the price. Because RO uncertain model could not be solved directly, RO uncertain model is transformed to RO certain model by elevator scheduling robust counterparts. Because solution space of elevator scheduling is enormous, to solve RO certain model in short time, ant colony solving algorithm for elevator scheduling is proposed. Based on the algorithm, optimal scheduling solutions are found quickly, and group elevators are scheduled according to the solutions. Simulation results show the method could improve scheduling performances effectively in peak pattern. Group elevators' efficient operation is realized by the RO scheduling method.

  17. Library Use

    DEFF Research Database (Denmark)

    Konzack, Lars

    2012-01-01

    A seminar paper about a survey of role-playing games in public libraries combined with three cases and a presentation of a model.......A seminar paper about a survey of role-playing games in public libraries combined with three cases and a presentation of a model....

  18. Automatic feature-based grouping during multiple object tracking.

    Science.gov (United States)

    Erlikhman, Gennady; Keane, Brian P; Mettler, Everett; Horowitz, Todd S; Kellman, Philip J

    2013-12-01

    Contour interpolation automatically binds targets with distractors to impair multiple object tracking (Keane, Mettler, Tsoi, & Kellman, 2011). Is interpolation special in this regard or can other features produce the same effect? To address this question, we examined the influence of eight features on tracking: color, contrast polarity, orientation, size, shape, depth, interpolation, and a combination (shape, color, size). In each case, subjects tracked 4 of 8 objects that began as undifferentiated shapes, changed features as motion began (to enable grouping), and returned to their undifferentiated states before halting. We found that intertarget grouping improved performance for all feature types except orientation and interpolation (Experiment 1 and Experiment 2). Most importantly, target-distractor grouping impaired performance for color, size, shape, combination, and interpolation. The impairments were, at times, large (>15% decrement in accuracy) and occurred relative to a homogeneous condition in which all objects had the same features at each moment of a trial (Experiment 2), and relative to a "diversity" condition in which targets and distractors had different features at each moment (Experiment 3). We conclude that feature-based grouping occurs for a variety of features besides interpolation, even when irrelevant to task instructions and contrary to the task demands, suggesting that interpolation is not unique in promoting automatic grouping in tracking tasks. Our results also imply that various kinds of features are encoded automatically and in parallel during tracking.

  19. CAN-SDI: experience with multi-source computer based current awareness services in the National Science Library, Ottawa.

    Science.gov (United States)

    Gaffney, I M

    1973-07-01

    CAN/SDI is Canada's national Selective Dissemination of Information Service offering a choice of nine data bases to its scientific and technical community. The system is based on central processing at the National Science Library combined with the utilization of decentralized expertise and resources for profile formulation and user education. Its greatest strength lies in its wide interdisciplinary quality. The major advantage of centralized processing of many data bases is that Canadians need learn only one method of profile formulation to access many files. A breakdown of services used confirms that a single tape service does not cover all the information requirements of most users. On the average each profile accesses approximately 1.5 data bases. Constant subscriber growth and a low cancellation rate indicate that CAN/SDI is and will continue to be an important element in Canada's information system.

  20. CCLab--a multi-objective genetic algorithm based combinatorial library design software and an application for histone deacetylase inhibitor design.

    Science.gov (United States)

    Fang, Guanghua; Xue, Mengzhu; Su, Mingbo; Hu, Dingyu; Li, Yanlian; Xiong, Bing; Ma, Lanping; Meng, Tao; Chen, Yuelei; Li, Jingya; Li, Jia; Shen, Jingkang

    2012-07-15

    The introduction of the multi-objective optimization has dramatically changed the virtual combinatorial library design, which can consider many objectives simultaneously, such as synthesis cost and drug-likeness, thus may increase positive rates of biological active compounds. Here we described a software called CCLab (Combinatorial Chemistry Laboratory) for combinatorial library design based on the multi-objective genetic algorithm. Tests of the convergence ability and the ratio to re-take the building blocks in the reference library were conducted to assess the software in silico, and then it was applied to a real case of designing a 5×6 HDAC inhibitor library. Sixteen compounds in the resulted library were synthesized, and the histone deactetylase (HDAC) enzymatic assays proved that 14 compounds showed inhibitory ratios more than 50% against tested 3 HDAC enzymes at concentration of 20 μg/mL, with IC(50) values of 3 compounds comparable to SAHA. These results demonstrated that the CCLab software could enhance the hit rates of the designed library and would be beneficial for medicinal chemists to design focused library in drug development (the software can be downloaded at: http://202.127.30.184:8080/drugdesign.html). Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Model for Sucker-Rod Pumping Unit Operating Modes Analysis Based on SimMechanics Library

    Science.gov (United States)

    Zyuzev, A. M.; Bubnov, M. V.

    2018-01-01

    The article provides basic information about the process of a sucker-rod pumping unit (SRPU) model developing by means of SimMechanics library in the MATLAB Simulink environment. The model is designed for the development of a pump productivity optimal management algorithms, sensorless diagnostics of the plunger pump and pumpjack, acquisition of the dynamometer card and determination of a dynamic fluid level in the well, normalization of the faulty unit operation before troubleshooting is performed by staff as well as equilibrium ratio determining by energy indicators and outputting of manual balancing recommendations to achieve optimal power consumption efficiency. Particular attention is given to the application of various blocks from SimMechanics library to take into account the pumpjack construction principal characteristic and to obtain an adequate model. The article explains in depth the developed tools features for collecting and analysis of simulated mechanism data. The conclusions were drawn about practical implementation possibility of the SRPU modelling results and areas for further development of investigation.

  2. Feature-based morphometry: discovering group-related anatomical patterns.

    Science.gov (United States)

    Toews, Matthew; Wells, William; Collins, D Louis; Arbel, Tal

    2010-02-01

    This paper presents feature-based morphometry (FBM), a new fully data-driven technique for discovering patterns of group-related anatomical structure in volumetric imagery. In contrast to most morphometry methods which assume one-to-one correspondence between subjects, FBM explicitly aims to identify distinctive anatomical patterns that may only be present in subsets of subjects, due to disease or anatomical variability. The image is modeled as a collage of generic, localized image features that need not be present in all subjects. Scale-space theory is applied to analyze image features at the characteristic scale of underlying anatomical structures, instead of at arbitrary scales such as global or voxel-level. A probabilistic model describes features in terms of their appearance, geometry, and relationship to subject groups, and is automatically learned from a set of subject images and group labels. Features resulting from learning correspond to group-related anatomical structures that can potentially be used as image biomarkers of disease or as a basis for computer-aided diagnosis. The relationship between features and groups is quantified by the likelihood of feature occurrence within a specific group vs. the rest of the population, and feature significance is quantified in terms of the false discovery rate. Experiments validate FBM clinically in the analysis of normal (NC) and Alzheimer's (AD) brain images using the freely available OASIS database. FBM automatically identifies known structural differences between NC and AD subjects in a fully data-driven fashion, and an equal error classification rate of 0.80 is achieved for subjects aged 60-80 years exhibiting mild AD (CDR=1). Copyright (c) 2009 Elsevier Inc. All rights reserved.

  3. Fuzzy forecasting based on fuzzy-trend logical relationship groups.

    Science.gov (United States)

    Chen, Shyi-Ming; Wang, Nai-Yi

    2010-10-01

    In this paper, we present a new method to predict the Taiwan Stock Exchange Capitalization Weighted Stock Index (TAIEX) based on fuzzy-trend logical relationship groups (FTLRGs). The proposed method divides fuzzy logical relationships into FTLRGs based on the trend of adjacent fuzzy sets appearing in the antecedents of fuzzy logical relationships. First, we apply an automatic clustering algorithm to cluster the historical data into intervals of different lengths. Then, we define fuzzy sets based on these intervals of different lengths. Then, the historical data are fuzzified into fuzzy sets to derive fuzzy logical relationships. Then, we divide the fuzzy logical relationships into FTLRGs for forecasting the TAIEX. Moreover, we also apply the proposed method to forecast the enrollments and the inventory demand, respectively. The experimental results show that the proposed method gets higher average forecasting accuracy rates than the existing methods.

  4. Age groups related glioblastoma study based on radiomics approach.

    Science.gov (United States)

    Li, Zeju; Wang, Yuanyuan; Yu, Jinhua; Guo, Yi; Zhang, Qi

    2017-12-01

    Glioblastoma is the most aggressive malignant brain tumor with poor prognosis. Radiomics is a newly emerging and promising technique to reveal the complex relationships between high-throughput medical image features and deep information of disease including pathology, biomarkers and genomics. An approach was developed to investigate the internal relationship between magnetic resonance imaging (MRI) features and the age-related origins of glioblastomas based on a quantitative radiomics method. A fully automatic image segmentation method was applied to segment the tumor regions from three dimensional MRI images. 555 features were then extracted from the image data. By analyzing large numbers of quantitative image features, some predictive and prognostic information could be obtained by the radiomics approach. 96 patients diagnosed with glioblastoma pathologically have been divided into two age groups (age groups (T test, p age difference (T test, p= .006). In conclusion, glioblastoma in different age groups present different radiomics-feature patterns with statistical significance, which indicates that glioblastoma in different age groups should have different pathologic, protein, or genic origins.

  5. Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library.

    Science.gov (United States)

    Shah, Falgun; Mukherjee, Prasenjit; Gut, Jiri; Legac, Jennifer; Rosenthal, Philip J; Tekwani, Babu L; Avery, Mitchell A

    2011-04-25

    Malaria, in particular that caused by Plasmodium falciparum , is prevalent across the tropics, and its medicinal control is limited by widespread drug resistance. Cysteine proteases of P. falciparum , falcipain-2 (FP-2) and falcipain-3 (FP-3), are major hemoglobinases, validated as potential antimalarial drug targets. Structure-based virtual screening of a focused cysteine protease inhibitor library built with soft rather than hard electrophiles was performed against an X-ray crystal structure of FP-2 using the Glide docking program. An enrichment study was performed to select a suitable scoring function and to retrieve potential candidates against FP-2 from a large chemical database. Biological evaluation of 50 selected compounds identified 21 diverse nonpeptidic inhibitors of FP-2 with a hit rate of 42%. Atomic Fukui indices were used to predict the most electrophilic center and its electrophilicity in the identified hits. Comparison of predicted electrophilicity of electrophiles in identified hits with those in known irreversible inhibitors suggested the soft-nature of electrophiles in the selected target compounds. The present study highlights the importance of focused libraries and enrichment studies in structure-based virtual screening. In addition, few compounds were screened against homologous human cysteine proteases for selectivity analysis. Further evaluation of structure-activity relationships around these nonpeptidic scaffolds could help in the development of selective leads for antimalarial chemotherapy.

  6. Cloning of low dose radiation induced gene RIG1 by RACE based on non-cloned cDNA library

    International Nuclear Information System (INIS)

    Luo Ying; Sui Jianli; Tie Yi; Zhang Yuanping; Zhou Pingkun; Sun Zhixian

    2001-01-01

    Objective: To obtain full-length cDNA of radiation induced new gene RIG1 based on its EST fragment. Methods: Based on non-cloned cDNA library, enhanced nested RACE PCR and biotin-avidin labelled probe for magnetic bead purification was used to obtain full-length cDNA of RIG1. Results: About 1 kb of 3' end of RIG1 gene was successfully cloned by this set of methods and cloning of RIG1 5' end is proceeding well. Conclusion: The result is consistent with the design of experiment. This set of protocol is useful for cloning of full-length gene based on EST fragment

  7. Summary report: working group 2 on 'Plasma Based Acceleration Concepts'

    International Nuclear Information System (INIS)

    Esarey, E.; Leemans, W.P.

    1998-01-01

    A summary of the talks, papers and discussion sessions presented in the Working Group on Plasma Based Acceleration Concepts is given within the context of the progress towards a 1 GeV laser driven accelerator module. The topics covered within the Working Group were self-modulated laser wakefield acceleration, standard laser wakefield acceleration, plasma beat wave acceleration, laser guiding and wake excitation in plasma channels, plasma wakefield acceleration, plasma lenses and optical injection techniques for laser wakefield accelerators. An overview will be given of the present status of experimental and theoretical progress as well as an outlook towards the future physics and technological challenges for the development of an optimized accelerator module

  8. Libraries Today, Libraries Tomorrow: Contemporary Library Practices and the Role of Library Space in the L

    Directory of Open Access Journals (Sweden)

    Ana Vogrinčič Čepič

    2013-09-01

    Full Text Available ABSTRACTPurpose: The article uses sociological concepts in order to rethink the changes in library practices. Contemporary trends are discussed with regard to the changing nature of working habits, referring mostly to the new technology, and the (emergence of the third space phenomenon. The author does not regard libraries only as concrete public service institutions, but rather as complex cultural forms, taking in consideration wider social context with a stress on users’ practices in relation to space.Methodology/approach: The article is based on the (self- observation of the public library use, and on the (discourse analysis of internal library documents (i.e. annual reports and plans and secondary sociological literature. As such, the cultural form approach represents a classic method of sociology of culture.Results: The study of relevant material in combination with direct personal experiences reveals socio-structural causes for the change of users’ needs and habits, and points at the difficulty of spatial redefinition of libraries as well as at the power of the discourse.Research limitations: The article is limited to an observation of users’ practices in some of the public libraries in Ljubljana and examines only a small number of annual reports – the discoveries are then further debated from the sociological perspective.Originality/practical implications: The article offers sociological insight in the current issues of the library science and tries to suggest a wider explanation that could answer some of the challenges of the contemporary librarianship.

  9. Grupo de Trabajo Para la Preparacion del Proyecto Sobre el Desarrolo de Servicias de Bibliotecas y de Informacion Cientifica y Tecnica (Working Group for the Preparation of the Proposal on the Development of Library Services and Scientific and Technical Information).

    Science.gov (United States)

    Oficina de Educacion Iberoamericana, Madrid (Spain).

    The Office of Iberoamerican Education, an intergovernmental body based on educational and cultural cooperation for the purpose of disseminating information, documentation, advice, and assistance in the field of education, co-sponsors (with UNESCO) the work represented in this study of library and information planning and facilities in the Andean…

  10. Developing European Library Services in Changing Times

    Directory of Open Access Journals (Sweden)

    Paul Ayris

    2012-04-01

    through changes to legal frameworks, and the paper looks at the Hargreaves review of copyright frameworks in the UK and the launch of the new library-based EU lobbying group for copyright reform, Information Sans Frontières (ISF.

  11. Library Research Support in Queensland: A Survey

    Science.gov (United States)

    Richardson, Joanna; Nolan-Brown, Therese; Loria, Pat; Bradbury, Stephanie

    2012-01-01

    University libraries worldwide are reconceptualising the ways in which they support the research agenda in their respective institutions. This paper is based on a survey completed by member libraries of the Queensland University Libraries Office of Cooperation (QULOC), the findings of which may be informative for other university libraries. After…

  12. Nigerian Libraries

    African Journals Online (AJOL)

    Bridging the digital divide: the potential role of the National Library of Nigeria · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Juliana Obiageri Akidi, Joy Chituru Onyenachi, 11-19 ...

  13. Library Locations

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Carnegie Library of Pittsburgh locations including address, coordinates, phone number, square footage, and standard operating hours. The map below does not display...

  14. academic libraries

    African Journals Online (AJOL)

    Information Impact: Journal of Information and Knowledge Management

    Information Impact: Journal of Information and Knowledge Management ... Key words: academic libraries, open access, research, researchers, technology ... European commission (2012) reports that affordable and easy access to the results ...

  15. Academic Libraries and Learning Support in Collaboration. Library Based Guidance for Peer Assisted Learning Leaders at Bournemouth University: Theory and Practice.

    OpenAIRE

    Parton, Steve; Fleming, Hugh

    2008-01-01

    This article begins with an overview of the University’s pioneering Peer Assisted Learning Scheme (PAL) and describes how in 2005/6, the Library became involved, collaborating with the PAL Coordinator to develop materials for use by PAL Leaders. PAL is intended to foster cross-year support between students on the same course. It encourages students to support each other and learn co-operatively under the guidance of trained students from the year above - called PAL Leaders. Two documents were...

  16. DevLore - A Firmware Library and Web-Based Configuration Control Tool for Accelerator Systems Under Constant Development

    International Nuclear Information System (INIS)

    Richard Evans; Kevin Jordan; Deborah Gruber; Daniel Sexton

    2005-01-01

    The Free Electron Laser Project at Jefferson Lab is based on a comparatively small accelerator driver. As it's systems continues to grow and evolve, strict configuration control has not been a programmatic goal. Conversely, as the IR-Demo FEL and the 10kW IR FEL have been built and operated, hardware and software changes have been regular part of the machine development process. With relatively small component counts for sub-systems, changes occur without requiring much formal documentation and in-situ alterations are common-place in the name of supporting operations. This paper presents an overview of the web-based software tool called DevLore which was first developed to be a library for embedded programming and then became a tremendously effective tool for tracking all changes made to the machine hardware and software

  17. Library-based discovery and characterization of daphnane diterpenes as potent and selective HIV inhibitors in Daphne gnidium.

    Science.gov (United States)

    Vidal, Vincent; Potterat, Olivier; Louvel, Séverine; Hamy, François; Mojarrab, Mahdi; Sanglier, Jean-Jacques; Klimkait, Thomas; Hamburger, Matthias

    2012-03-23

    Despite the existence of an extended armamentarium of effective synthetic drugs to treat HIV, there is a continuing need for new potent and affordable drugs. Given the successful history of natural product based drug discovery, a library of close to one thousand plant and fungal extracts was screened for antiretroviral activity. A dichloromethane extract of the aerial parts of Daphne gnidium exhibited strong antiretroviral activity and absence of cytotoxicity. With the aid of HPLC-based activity profiling, the antiviral activity could be tracked to four daphnane derivatives, namely, daphnetoxin (1), gnidicin (2), gniditrin (3), and excoecariatoxin (4). Detailed anti-HIV profiling revealed that the pure compounds were active against multidrug-resistant viruses irrespective of their cellular tropism. Mode of action studies that narrowed the site of activity to viral entry events suggested a direct interference with the expression of the two main HIV co-receptors, CCR5 and CXCR4, at the cell surface by daphnetoxin (1).

  18. A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties

    Science.gov (United States)

    Tiller, Thomas; Schuster, Ingrid; Deppe, Dorothée; Siegers, Katja; Strohner, Ralf; Herrmann, Tanja; Berenguer, Marion; Poujol, Dominique; Stehle, Jennifer; Stark, Yvonne; Heßling, Martin; Daubert, Daniela; Felderer, Karin; Kaden, Stefan; Kölln, Johanna; Enzelberger, Markus; Urlinger, Stefanie

    2013-01-01

    This report describes the design, generation and testing of Ylanthia, a fully synthetic human Fab antibody library with 1.3E+11 clones. Ylanthia comprises 36 fixed immunoglobulin (Ig) variable heavy (VH)/variable light (VL) chain pairs, which cover a broad range of canonical complementarity-determining region (CDR) structures. The variable Ig heavy and Ig light (VH/VL) chain pairs were selected for biophysical characteristics favorable to manufacturing and development. The selection process included multiple parameters, e.g., assessment of protein expression yield, thermal stability and aggregation propensity in fragment antigen binding (Fab) and IgG1 formats, and relative Fab display rate on phage. The framework regions are fixed and the diversified CDRs were designed based on a systematic analysis of a large set of rearranged human antibody sequences. Care was taken to minimize the occurrence of potential posttranslational modification sites within the CDRs. Phage selection was performed against various antigens and unique antibodies with excellent biophysical properties were isolated. Our results confirm that quality can be built into an antibody library by prudent selection of unmodified, fully human VH/VL pairs as scaffolds. PMID:23571156

  19. A cluster-based strategy for assessing the overlap between large chemical libraries and its application to a recent acquisition.

    Science.gov (United States)

    Engels, Michael F M; Gibbs, Alan C; Jaeger, Edward P; Verbinnen, Danny; Lobanov, Victor S; Agrafiotis, Dimitris K

    2006-01-01

    We report on the structural comparison of the corporate collections of Johnson & Johnson Pharmaceutical Research & Development (JNJPRD) and 3-Dimensional Pharmaceuticals (3DP), performed in the context of the recent acquisition of 3DP by JNJPRD. The main objective of the study was to assess the druglikeness of the 3DP library and the extent to which it enriched the chemical diversity of the JNJPRD corporate collection. The two databases, at the time of acquisition, collectively contained more than 1.1 million compounds with a clearly defined structural description. The analysis was based on a clustering approach and aimed at providing an intuitive quantitative estimate and visual representation of this enrichment. A novel hierarchical clustering algorithm called divisive k-means was employed in combination with Kelley's cluster-level selection method to partition the combined data set into clusters, and the diversity contribution of each library was evaluated as a function of the relative occupancy of these clusters. Typical 3DP chemotypes enriching the diversity of the JNJPRD collection were catalogued and visualized using a modified maximum common substructure algorithm. The joint collection of JNJPRD and 3DP compounds was also compared to other databases of known medicinally active or druglike compounds. The potential of the methodology for the analysis of very large chemical databases is discussed.

  20. eMarketing for Libraries

    OpenAIRE

    Fernández-Marcial, Viviana

    2013-01-01

    These days advertorials, microsites, social networks, blogging and viral videos are just some manifestations of promoting libraries. E-marketing brings opportunities for libraries to connect whith their target groups. Different publications show how library users are esenciatially digital citizens and with e-marketing it is possible to connect with the users in their own natural habitat. It is also allows spreading a message with a lower cost than other strategies.

  1. SpacePy - a Python-based library of tools for the space sciences

    International Nuclear Information System (INIS)

    Morley, Steven K.; Welling, Daniel T.; Koller, Josef; Larsen, Brian A.; Henderson, Michael G.

    2010-01-01

    Space science deals with the bodies within the solar system and the interplanetary medium; the primary focus is on atmospheres and above - at Earth the short timescale variation in the the geomagnetic field, the Van Allen radiation belts and the deposition of energy into the upper atmosphere are key areas of investigation. SpacePy is a package for Python, targeted at the space sciences, that aims to make basic data analysis, modeling and visualization easier. It builds on the capabilities of the well-known NumPy and MatPlotLib packages. Publication quality output direct from analyses is emphasized. The SpacePy project seeks to promote accurate and open research standards by providing an open environment for code development. In the space physics community there has long been a significant reliance on proprietary languages that restrict free transfer of data and reproducibility of results. By providing a comprehensive, open-source library of widely used analysis and visualization tools in a free, modern and intuitive language, we hope that this reliance will be diminished. SpacePy includes implementations of widely used empirical models, statistical techniques used frequently in space science (e.g. superposed epoch analysis), and interfaces to advanced tools such as electron drift shell calculations for radiation belt studies. SpacePy also provides analysis and visualization tools for components of the Space Weather Modeling Framework - currently this only includes the BATS-R-US 3-D magnetohydrodynamic model and the RAM ring current model - including streamline tracing in vector fields. Further development is currently underway. External libraries, which include well-known magnetic field models, high-precision time conversions and coordinate transformations are wrapped for access from Python using SWIG and f2py. The rest of the tools have been implemented directly in Python. The provision of open-source tools to perform common tasks will provide openness in the

  2. Group size, grooming and fission in primates: a modeling approach based on group structure.

    Science.gov (United States)

    Sueur, Cédric; Deneubourg, Jean-Louis; Petit, Odile; Couzin, Iain D

    2011-03-21

    In social animals, fission is a common mode of group proliferation and dispersion and may be affected by genetic or other social factors. Sociality implies preserving relationships between group members. An increase in group size and/or in competition for food within the group can result in decrease certain social interactions between members, and the group may split irreversibly as a consequence. One individual may try to maintain bonds with a maximum of group members in order to keep group cohesion, i.e. proximity and stable relationships. However, this strategy needs time and time is often limited. In addition, previous studies have shown that whatever the group size, an individual interacts only with certain grooming partners. There, we develop a computational model to assess how dynamics of group cohesion are related to group size and to the structure of grooming relationships. Groups' sizes after simulated fission are compared to observed sizes of 40 groups of primates. Results showed that the relationship between grooming time and group size is dependent on how each individual attributes grooming time to its social partners, i.e. grooming a few number of preferred partners or grooming equally or not all partners. The number of partners seemed to be more important for the group cohesion than the grooming time itself. This structural constraint has important consequences on group sociality, as it gives the possibility of competition for grooming partners, attraction for high-ranking individuals as found in primates' groups. It could, however, also have implications when considering the cognitive capacities of primates. Copyright © 2010 Elsevier Ltd. All rights reserved.

  3. Any of them will do: In-group identification, out-group entitativity, and gang membership as predictors of group-based retribution.

    Science.gov (United States)

    Vasquez, Eduardo A; Wenborne, Lisa; Peers, Madeline; Alleyne, Emma; Ellis, Kirsty

    2015-05-01

    In non-gang populations, the degree of identification with an in-group and perceptions of out-group entitativity, the perception of an out-group as bonded or unified, are important contributors to group-based aggression or vicarious retribution. The link between these factors and group-based aggression, however, has not been examined in the context of street gangs. The current study assessed the relationship among in-group identification, perceptions of out-group entitativity, and the willingness to retaliate against members of rival groups who did not themselves attack the in-group among juvenile gang and non-gang members in London. Our results showed the predicted membership (gang/non-gang) × in-group identification × entitativity interaction. Decomposition of the three-way interaction by membership revealed a significant identification × entitativity interaction for gang, but not for non-gang members. More specifically, gang members who identify more strongly with their gang and perceived a rival group as high on entitativity were more willing to retaliate against any of them. In addition, entitativity was a significant predictor of group-based aggression after controlling for gender, in-group identification, and gang membership. Our results are consistent with socio-psychological theories of group-based aggression and support the proposal that such theories are applicable for understanding gang-related violence. Aggr. Behav. 41:242-252, 2015. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  4. Identifying and Exploring Future Trends Impacting on Academic Libraries: A Mixed Methodology Using Journal Content Analysis, Focus Groups, and Trend Reports

    Science.gov (United States)

    Gwyer, Roisin

    2015-01-01

    This article compares three sources of information about academic libraries to consider what the future could hold and the skills needed to deliver effective services within that future. The starting point is the contents of "New Review of Academic Librarianship" (formerly "British Journal of Academic Librarianship") from 1986,…

  5. Cross sections in 25 groups obtained from ENDF/B-IV and ENDL/78 libraries, processed with GALAXY and NJOY computer codes

    International Nuclear Information System (INIS)

    Chalhoub, E.S.; Corcuera, R.P.

    1982-01-01

    The discrepancies existing between ENDF/B-IV and ENDL/78 libraries, in diferent energy regions are identified, and the order of the differences in multigroup sections are determined, when GALAXY or NJOY computer codes are used. (E.G.) [pt

  6. Comprehensive Assessment of Models and Events based on Library tools (CAMEL)

    Science.gov (United States)

    Rastaetter, L.; Boblitt, J. M.; DeZeeuw, D.; Mays, M. L.; Kuznetsova, M. M.; Wiegand, C.

    2017-12-01

    At the Community Coordinated Modeling Center (CCMC), the assessment of modeling skill using a library of model-data comparison metrics is taken to the next level by fully integrating the ability to request a series of runs with the same model parameters for a list of events. The CAMEL framework initiates and runs a series of selected, pre-defined simulation settings for participating models (e.g., WSA-ENLIL, SWMF-SC+IH for the heliosphere, SWMF-GM, OpenGGCM, LFM, GUMICS for the magnetosphere) and performs post-processing using existing tools for a host of different output parameters. The framework compares the resulting time series data with respective observational data and computes a suite of metrics such as Prediction Efficiency, Root Mean Square Error, Probability of Detection, Probability of False Detection, Heidke Skill Score for each model-data pair. The system then plots scores by event and aggregated over all events for all participating models and run settings. We are building on past experiences with model-data comparisons of magnetosphere and ionosphere model outputs in GEM2008, GEM-CEDAR CETI2010 and Operational Space Weather Model challenges (2010-2013). We can apply the framework also to solar-heliosphere as well as radiation belt models. The CAMEL framework takes advantage of model simulations described with Space Physics Archive Search and Extract (SPASE) metadata and a database backend design developed for a next-generation Run-on-Request system at the CCMC.

  7. Populating a Library of Reusable H-Boms Assessment of a Feasible Image Based Modeling Workflow

    Science.gov (United States)

    Santagati, C.; Lo Turco, M.; D'Agostino, G.

    2017-08-01

    The paper shows the intermediate results of a research activity aimed at populating a library of reusable Historical Building Object Models (H-BOMs) by testing a full digital workflow that takes advantages from using Structure from Motion (SfM) models and is centered on the geometrical/stylistic/materic analysis of the architectural element (portal, window, altar). The aim is to find common (invariant) and uncommon (variant) features in terms of identification of architectural parts and their relationships, geometrical rules, dimensions and proportions, construction materials and measure units, in order to model archetypal shapes from which it is possible to derive all the style variations. At this regard, a set of 14th - 16th century gothic portals of the catalan-aragonese architecture in Etnean area of Eastern Sicily has been studied and used to assess the feasibility of the identified workflow. This approach tries to answer the increasingly demand for guidelines and standards in the field of Cultural Heritage Conservation to create and manage semantic-aware 3D models able to include all the information (both geometrical and alphanumerical ones) concerning historical buildings and able to be reused in several projects.

  8. Hardware Accelerators Targeting a Novel Group Based Packet Classification Algorithm

    Directory of Open Access Journals (Sweden)

    O. Ahmed

    2013-01-01

    Full Text Available Packet classification is a ubiquitous and key building block for many critical network devices. However, it remains as one of the main bottlenecks faced when designing fast network devices. In this paper, we propose a novel Group Based Search packet classification Algorithm (GBSA that is scalable, fast, and efficient. GBSA consumes an average of 0.4 megabytes of memory for a 10 k rule set. The worst-case classification time per packet is 2 microseconds, and the preprocessing speed is 3 M rules/second based on an Xeon processor operating at 3.4 GHz. When compared with other state-of-the-art classification techniques, the results showed that GBSA outperforms the competition with respect to speed, memory usage, and processing time. Moreover, GBSA is amenable to implementation in hardware. Three different hardware implementations are also presented in this paper including an Application Specific Instruction Set Processor (ASIP implementation and two pure Register-Transfer Level (RTL implementations based on Impulse-C and Handel-C flows, respectively. Speedups achieved with these hardware accelerators ranged from 9x to 18x compared with a pure software implementation running on an Xeon processor.

  9. Arriba-lib: association of an evidence-based electronic library of decision aids with communication and decision-making in patients and primary care physicians.

    Science.gov (United States)

    Hirsch, Oliver; Keller, Heidemarie; Krones, Tanja; Donner-Banzhoff, Norbert

    2012-03-01

    In shared decision-making, patients are empowered to actively ask questions and participate in decisions about their healthcare based on their preferences and values. Decision aids should help patients make informed choices among diagnostic or treatment options by delivering evidence-based information on options and outcomes; however, they have rarely been field tested, especially in the primary care context. We therefore evaluated associations between the use of an interactive, transactional and evidence-based library of decision aids (arriba-lib) and communication and decision-making in patients and physicians in the primary care context. Our electronic library of decision aids ('arriba-lib') includes evidence-based modules for cardiovascular prevention, diabetes, coronary heart disease, atrial fibrillation and depression. Twenty-nine primary care physicians recruited 192 patients. We used questionnaires to ask patients and physicians about their experiences with and attitudes towards the programme. Patients were interviewed via telephone 2 months after the consultation. Data were analysed by general estimation equations, cross tab analyses and by using effect sizes. Only a minority (8.9%) of the consultations were felt to be too long because physicians said consultations were unacceptably extended by arriba-lib. We found a negative association between the detailedness of the discussion of the clinical problem's definition and the age of the patients. Physicians discuss therapeutic options in less detail with patients who have a formal education of less than 8 years. Patients who were counselled by a physician with no experience in using a decision aid more often reported that they do not remember being counselled with the help of a decision aid or do not wish to be counselled again with a decision aid. Arriba-lib has positive associations to the decision-making process in patients and physicians. It can also be used with older age groups and patients with less

  10. Clustering of users of digital libraries through log file analysis

    Directory of Open Access Journals (Sweden)

    Juan Antonio Martínez-Comeche

    2017-09-01

    Full Text Available This study analyzes how users perform information retrieval tasks when introducing queries to the Hispanic Digital Library. Clusters of users are differentiated based on their distinct information behavior. The study used the log files collected by the server over a year and different possible clustering algorithms are compared. The k-means algorithm is found to be a suitable clustering method for the analysis of large log files from digital libraries. In the case of the Hispanic Digital Library the results show three clusters of users and the characteristic information behavior of each group is described.

  11. ZZ TEMPEST/MUFT, Thermal Neutron and Fast Neutron Multigroup Cross-Section Library for Program LEOPARD

    International Nuclear Information System (INIS)

    Kim, Jung-Do; Lee, Jong Tai

    1986-01-01

    Description of problem or function: Format: TEMPEST and MUFT; Number of groups: 246 thermal groups in TEMPEST Format and 54 fast groups in MUFT Format. From this library, the program SPOTS4 generates a 172-54 group library as input to the code LEOPARD. Nuclides: H, O, Zr, C, Fe, Ni, Al, Cr, Mn, U, Pu, Th, Pa, Xe, Sm, B and D. Origin: ENDF/B-4; Weighting spectrum: 1/E + U 235 fission spectrum. Data library of thermal and fast neutron group Cross sections to generate input to the program LEOPARD. The data is based on ENDF/B-4 and consists of two parts: (1) 246 thermal groups in TEMPEST Format. (2) 54 fast groups in MUFT Format. From this library, the program SPOTS4 generates a 172-54 group library as input to the code LEOPARD (NESC0279)

  12. Analysis of PROTEUS phase II experiments performed using the AARE modular system and JEF-based libraries

    International Nuclear Information System (INIS)

    Pelloni, S.; Stepanek, J.; Vontobel, P.

    1989-01-01

    The capability of the advanced analysis of reactor engineering (AARE) modular code system and JEF-1-based nuclear data libraries to analyze light water high converter reactor (LWHCR) lattices is investigated by calculating the wet and dry cells of the PROTEUS-LWHCR phase II experiment. The results are compared to those obtained using several cell codes. Main features of the AARE code system, such as the self-shielding of resonance cross sections in the whole energy range, the generation of adequate fission source spectra, and the efficiency of the elastic removal correction,are investigated. In particular, it is shown that AARE results for the k ∞ void coefficient agree very well with the experiment, whereas other codes give larger deviations

  13. Validation of LWR calculation methods and JEF-1 based data libraries by TRX and BAPL critical experiments

    International Nuclear Information System (INIS)

    Pelloni, S.; Grimm, P.; Mathews, D.; Paratte, J.M.

    1989-06-01

    In this report the capability of various code systems widely used at PSI (such as WIMS-D, BOXER, and the AARE modules TRAMIX and MICROX-2 in connection with the one-dimensional transport code ONEDANT) and JEF-1 based nuclear data libraries to compute LWR lattices is analysed by comparing results from thermal reactor benchmarks TRX and BAPL with experiment and with previously published values. It is shown that with the JEF-1 evaluation eigenvalues are generally well predicted within 8 mk (1 mk = 0.001) or less by all code systems, and that all methods give reasonable results for the measured reaction rate within or not too far from the experimental uncertainty. This is consistent with previous similar studies. (author) 7 tabs., 36 refs

  14. The spectra program library: A PC based system for gamma-ray spectra analysis and INAA data reduction

    Science.gov (United States)

    Baedecker, P.A.; Grossman, J.N.

    1995-01-01

    A PC based system has been developed for the analysis of gamma-ray spectra and for the complete reduction of data from INAA experiments, including software to average the results from mulitple lines and multiple countings and to produce a final report of analysis. Graphics algorithms may be called for the analysis of complex spectral features, to compare the data from alternate photopeaks and to evaluate detector performance during a given counting cycle. A database of results for control samples can be used to prepare quality control charts to evaluate long term precision and to search for systemic variations in data on reference samples as a function of time. The entire software library can be accessed through a user-friendly menu interface with internal help.

  15. Library Services Funding Assessment

    Science.gov (United States)

    Lorig, Jonathan A.

    2004-01-01

    The Glenn Technical Library is a science and engineering library that primarily supports research activities at the Glenn Research Center, and provides selected services to researchers at all of the NASA research centers. Resources available in the library include books, journals, CD-ROMs, and access to various online sources, as well as live reference and inter-library loan services. The collection contains over 77,000 books, 800,000 research reports, and print or online access to over 1,400 journals. Currently the library operates within the Logistics and Technical Information Division, and is funded as an open-access resource within the GRC. Some of the research units at the GRC have recently requested that the library convert to a "pay-for-services" model, in which individual research units could fund only those journal subscriptions for which they have a specific need. Under this model, the library would always maintain a certain minimum level of pooled-expense services, including the ready reference and book collections, and inter-library loan services. Theoretically the "pay-for-services" model would encourage efficient financial allocation, and minimize the extent to which paid journal subscriptions go unused. However, this model also could potentially negate the benefits of group purchases for journal subscriptions and access. All of the major journal publishers offer package subscriptions that compare favorably in cost with the sum of individual subscription costs for a similar selection of titles. Furthermore, some of these subscription packages are "consortium" purchases that are funded collectively by the libraries at multiple NASA research centers; such consortia1 memberships would be difficult for the library to pay, if enough GRC research units were to withdraw their pooled contributions. cost of collectively-funded journal access with the cost of individual subscriptions. My primary task this summer is to create the cost dataset framework, and

  16. National nostalgia : A group-based emotion that benefits the in-group but hampers intergroup relations

    NARCIS (Netherlands)

    Smeekes, A.N.

    2015-01-01

    Social psychological research on nostalgia has mainly considered this emotion at the individual level rather than the group level. The current paper proposes that group-based nostalgia for the nation (i.e., national nostalgia) is likely to be related to a positive in-group orientation and a negative

  17. How Perspective-Taking Helps and Hinders Group-Based Guilt as a Function of Group Identification

    NARCIS (Netherlands)

    Zebel, Sven; Doosje, Bertjan; Spears, Russell

    In two studies we hypothesized that outgroup perspective-taking promotes group-based guilt among weakly identified perpetrator group members, but hinders it among higher identifiers. In Study 1, native Dutch participants (N = 153) confronted their group's past mistreatment of outgroups, while

  18. Group Contribution Based Process Flowsheet Synthesis, Design and Modelling

    DEFF Research Database (Denmark)

    d'Anterroches, Loïc; Gani, Rafiqul

    2005-01-01

    In a group contribution method for pure component property prediction, a molecule is described as a set of groups linked together to form a molecular structure. In the same way, for flowsheet "property" prediction, a flowsheet can be described as a set of process-groups linked together to represent...... the flowsheet structure. Just as a functional group is a collection of atoms, a process-group is a collection of operations forming an "unit" operation or a set of "unit" operations. The link between the process-groups are the streams similar to the bonds that are attachments to atoms/groups. Each process-group...... provides a contribution to the "property" of the flowsheet, which can be performance in terms of energy consumption, thereby allowing a flowsheet "property" to be calculated, once it is described by the groups. Another feature of this approach is that the process-group attachments provide automatically...

  19. Initial draft of CSE-UCLA evaluation model based on weighted product in order to optimize digital library services in computer college in Bali

    Science.gov (United States)

    Divayana, D. G. H.; Adiarta, A.; Abadi, I. B. G. S.

    2018-01-01

    The aim of this research was to create initial design of CSE-UCLA evaluation model modified with Weighted Product in evaluating digital library service at Computer College in Bali. The method used in this research was developmental research method and developed by Borg and Gall model design. The results obtained from the research that conducted earlier this month was a rough sketch of Weighted Product based CSE-UCLA evaluation model that the design had been able to provide a general overview of the stages of weighted product based CSE-UCLA evaluation model used in order to optimize the digital library services at the Computer Colleges in Bali.

  20. The Strategic Role of Digital Libraries: Issues in E-Learning Environments.

    Science.gov (United States)

    Wang, Mei-Yu

    2003-01-01

    Describes research aimed at providing educational organizations with practical strategies for implementing electronic learning (e-learning), based on focus group discussions at an elementary school in Taiwan. Considers the strategic role of digital libraries in electronic learning environments, library collections, digital technology, human…

  1. The library

    International Nuclear Information System (INIS)

    1980-01-01

    A specialized library is essential for conducting the research work of the Uranium Institute. The need was recognized at the foundation of the Institute and a full-time librarian was employed in 1976 to establish the necessary systems and begin the task of building up the collection. A brief description is given of the services offered by the library which now contains books, periodicals, pamphlets and press cuttings, focussed on uranium and nuclear energy, but embracing economics, politics, trade, legislation, geology, mining and mineral processing, environmental protection and nuclear technology. (author)

  2. Bridging the Gap of Practice and Research: A Preliminary Investigation of Evidence-based Practice for Library and Information Science Research

    Directory of Open Access Journals (Sweden)

    吳寂絹 Chi-Chuan Wu

    2015-10-01

    Full Text Available The gap between practice and research is commonly found in disciplines with both ofprofessional practitioners and academic researchers. How to bridge the gap is also acontinuing concern in the field of Library and Information Studies. This article describes therecent development of Evidence-based Practice for Library and Information ScienceResearch (EBLIP, and provides analysis of the journal EBLIP including its authors’backgrounds, methods, and topics. The results show that the United States and Canadaare the two major nations of contributors; more than 70% of first authors are librarians; 76%of the articles were contributed by one single institute, co-authorship by cross-nationinstitutes were rarely seen, and demonstrates local research interests; type of co-authoredagency is primarily among libraries; 60% methods employed include questionnaires,interviews and content analysis; the coverage of topics is rather broad, and the top threecategories of research topics include Information Literacy & Instruction, Information Needs& Seeking Behavior, and Reference Services / Digital Reference Services (15%, 10%, and8%; many datasets were obtained from real library practice, and 72% of articles provide specific implications for applications which highlight the value of implementation. Manylibrarians have the research capability, and this article serves as a purpose to introduce theevidence-based research and encourage more such research done in Taiwan. Hopefully itmay benefit and further enhance the quality of library decision-making and their professionalimage.

  3. Libraries on the MOVE.

    Science.gov (United States)

    Edgar, Jim; And Others

    1986-01-01

    Presents papers from Illinois State Library and Shawnee Library System's "Libraries on the MOVE" conference focusing on how libraries can impact economic/cultural climate of an area. Topics addressed included information services of rural libraries; marketing; rural library development; library law; information access; interagency…

  4. Personal Virtual Libraries

    Science.gov (United States)

    Pappas, Marjorie L.

    2004-01-01

    Virtual libraries are becoming more and more common. Most states have a virtual library. A growing number of public libraries have a virtual presence on the Web. Virtual libraries are a growing addition to school library media collections. The next logical step would be personal virtual libraries. A personal virtual library (PVL) is a collection…

  5. Gender-based education during clerkships: a focus group study

    Directory of Open Access Journals (Sweden)

    van Leerdam L

    2014-02-01

    Full Text Available Lotte van Leerdam, Lianne Rietveld, Doreth Teunissen, Antoine Lagro-JanssenDepartment of Primary and Community Care, Gender and Women's Health, Radboud University Medical Center, Nijmegen, The NetherlandsObjectives: One of the goals of the medical master's degree is for a student to become a gender-sensitive doctor by applying knowledge of gender differences in practice. This study aims to investigate, from the students’ perspective, whether gender medicine has been taught in daily practice during clerkship.Methods: A focus group study was conducted among 29 medical students from Radboud University, Nijmegen, The Netherlands, who had just finished either their internal medicine or surgical clerkships. Data were analyzed in line with the principles of constant comparative analysis.Results: Four focus groups were conducted with 29 participating students. Clinical teachers barely discuss gender differences during students’ clerkships. The students mentioned three main explanatory themes: insufficient knowledge; unawareness; and minor impact. As a result, students feel that they have insufficient competencies to become gender-sensitive doctors.Conclusion: Medical students at our institution perceive that they have received limited exposure to gender-based education after completing two key clinical clerkships. All students feel that they have insufficient knowledge to become gender-sensitive doctors. They suppose that their clinical teachers have insufficient knowledge regarding gender sensitivity, are unaware of gender differences, and the students had the impression that gender is not regarded as an important issue. We suggest that the medical faculty should encourage clinical teachers to improve their knowledge and awareness of gender issues.Keywords: medical education, clerkship, gender, hidden curriculum, clinical teachers

  6. Connection-based and object-based grouping in multiple-object tracking: A developmental study

    OpenAIRE

    Hallen, Ruth; Reusens, J. (Julie); Evers, K. (Kris); de-Wit, Lee; Wagemans, Johan

    2018-01-01

    textabstractDevelopmental research on Gestalt laws has previously revealed that, even as young as infancy, we are bound to group visual elements into unitary structures in accordance with a variety of organizational principles. Here, we focus on the developmental trajectory of both connection-based and object-based grouping, and investigate their impact on object formation in participants, aged 9-21 years old (N = 113), using a multiple-object tracking paradigm. Results reveal a main effect o...

  7. Polymer containing functional end groups is base for new polymers

    Science.gov (United States)

    Hirshfield, S. M.

    1971-01-01

    Butadiene is polymerized with lithium-p-lithiophenoxide to produce linear polymer containing oxy-lithium group at one end and active carbon-lithium group at other end. Living polymers represent new approach to preparation of difunctional polymers in which structural features, molecular weight, type and number of end groups are controlled.

  8. Library services and user satisfaction in developing countries: a case study.

    Science.gov (United States)

    Mairaj, Muhammad Ijaz; Naseer, Mirza Muhammad

    2013-12-01

    Punjab Institute of Cardiology (PIC) is a recognised teaching hospital for cardiac care in the Punjab province of Pakistan. PIC has established a library to fulfil the research and information needs of health care professionals. This study aims to evaluate the satisfaction of users with the services of PIC library. A purposive sample of 15 health care professionals was selected. A semistructured interview technique based on an interview guide was used for collection of data. The data were qualitatively analysed using a thematic approach. Users of PIC library were satisfied with the library collection, organisation, reference and circulation services, staff attitudes, cooling and heating. They were concerned about library space, hours, furniture and environment, and suggested more availability of electronic library services, newer collections, better Internet access and comfortable furniture. The study proved useful to investigate users' satisfaction with the services of PIC library. It concludes that the PIC library should maintain and strengthen the services with which users are satisfied, and improve those about which they are concerned. The study will be useful to libraries in other developing countries for improvement in their services. © 2013 The authors. Health Information and Libraries Journal © 2013 Health Libraries Group.

  9. Application of a new cross section library based on ENDF/B-IV to reactor core analysis

    International Nuclear Information System (INIS)

    Lima Bezerra, J. de.

    1991-04-01

    The use of the ENDF/B-IV library in the LEOPARD code for the Angra-1 reactor simulation is presented. The results are compared to those obtained using the ENDF/B-II library and show better values for the power distribution but an underestimated global reactivity as compared to experimental results. (F.E.). 1 ref, 55 figs, 1 tab

  10. An Intelligent Mobile Location-Aware Book Recommendation System that Enhances Problem-Based Learning in Libraries

    Science.gov (United States)

    Chen, Chih-Ming

    2013-01-01

    Despite rapid and continued adoption of mobile devices, few learning modes integrate with mobile technologies and libraries' environments as innovative learning modes that emphasize the key roles of libraries in facilitating learning. In addition, some education experts have claimed that transmitting knowledge to learners is not the only…

  11. Out on the Web: The Relationship between Campus Climate and GLBT-Related Web-based Resources in Academic Libraries

    Science.gov (United States)

    Ciszek, Matthew P.

    2011-01-01

    This article explores the relationship between the perceived campus environment for gay, lesbian, bisexual, and transgender (GLBT) students at colleges and universities and how academic libraries have deployed GLBT-related resources on the Web. Recommendations are made for increasing GLBT-related materials and information in academic libraries.…

  12. Studer Group® ' s evidence-based leadership initiatives.

    Science.gov (United States)

    Schuller, Kristin A; Kash, Bita A; Gamm, Larry D

    2015-01-01

    The purpose of this paper is to analyze the implementation of an organizational change initiative--Studer Group®'s Evidence-Based Leadership (EBL)--in two large, US health systems by comparing and contrasting the factors associated with successful implementation and sustainability of the EBL initiative. This comparative case study assesses the responses to two pairs of open-ended questions during in-depth qualitative interviews of leaders and managers at both health systems. Qualitative content analysis was employed to identify major themes. Three themes associated with success and sustainability of EBL emerged at both health systems: leadership; culture; and organizational processes. The theme most frequently identified for both success and sustainability of EBL was culture. In contrast, there was a significant decline in salience of the leadership theme as attention shifts from success in implementation of EBL to sustaining EBL long term. Within the culture theme, accountability, and buy-in were most often cited by interviewees as success factors, while sense of accountability, buy-in, and communication were the most reported factors for sustainability. Cultural factors, such as accountability, staff support, and communication are driving forces of success and sustainability of EBL across both health systems. Leadership, a critical factor in several stages of implementation, appears to be less salient as among factors identified as important to longer term sustainability of EBL.

  13. A group signature scheme based on quantum teleportation

    International Nuclear Information System (INIS)

    Wen Xiaojun; Tian Yuan; Ji Liping; Niu Xiamu

    2010-01-01

    In this paper, we present a group signature scheme using quantum teleportation. Different from classical group signature and current quantum signature schemes, which could only deliver either group signature or unconditional security, our scheme guarantees both by adopting quantum key preparation, quantum encryption algorithm and quantum teleportation. Security analysis proved that our scheme has the characteristics of group signature, non-counterfeit, non-disavowal, blindness and traceability. Our quantum group signature scheme has a foreseeable application in the e-payment system, e-government, e-business, etc.

  14. A group signature scheme based on quantum teleportation

    Energy Technology Data Exchange (ETDEWEB)

    Wen Xiaojun; Tian Yuan; Ji Liping; Niu Xiamu, E-mail: wxjun36@gmail.co [Information Countermeasure Technique Research Institute, Harbin Institute of Technology, Harbin 150001 (China)

    2010-05-01

    In this paper, we present a group signature scheme using quantum teleportation. Different from classical group signature and current quantum signature schemes, which could only deliver either group signature or unconditional security, our scheme guarantees both by adopting quantum key preparation, quantum encryption algorithm and quantum teleportation. Security analysis proved that our scheme has the characteristics of group signature, non-counterfeit, non-disavowal, blindness and traceability. Our quantum group signature scheme has a foreseeable application in the e-payment system, e-government, e-business, etc.

  15. Library Automation.

    Science.gov (United States)

    Husby, Ole

    1990-01-01

    The challenges and potential benefits of automating university libraries are reviewed, with special attention given to cooperative systems. Aspects discussed include database size, the role of the university computer center, storage modes, multi-institutional systems, resource sharing, cooperative system management, networking, and intelligent…

  16. Application Portable Parallel Library

    Science.gov (United States)

    Cole, Gary L.; Blech, Richard A.; Quealy, Angela; Townsend, Scott

    1995-01-01

    Application Portable Parallel Library (APPL) computer program is subroutine-based message-passing software library intended to provide consistent interface to variety of multiprocessor computers on market today. Minimizes effort needed to move application program from one computer to another. User develops application program once and then easily moves application program from parallel computer on which created to another parallel computer. ("Parallel computer" also include heterogeneous collection of networked computers). Written in C language with one FORTRAN 77 subroutine for UNIX-based computers and callable from application programs written in C language or FORTRAN 77.

  17. Knowledge management for libraries

    CERN Document Server

    Forrestal, Valerie

    2015-01-01

    Libraries are creating dynamic knowledge bases to capture both tacit and explicit knowledge and subject expertise for use within and beyond their organizations. In this book, readers will learn to move policies and procedures manuals online using a wiki, get the most out of Microsoft SharePoint with custom portals and Web Parts, and build an FAQ knowledge base from reference management applications such as LibAnswers. Knowledge Management for Libraries guides readers through the process of planning, developing, and launching th

  18. SU-F-T-47: MRI T2 Exclusive Based Planning Using the Endocavitary/interstitial Gynecological Benidorm Applicator: A Proposed TPS Library and Preplan Efficient Methodology

    Energy Technology Data Exchange (ETDEWEB)

    Richart, J; Otal, A; Rodriguez, S; Santos, M [Clinica Benidorm, Benidorm, Alicante (Spain); Perez-Calatayud, J [Clinica Benidorm, Benidorm, Alicante (Spain); Hospital La Fe, Valencia (Spain)

    2016-06-15

    Purpose: ABS and GEC-ESTRO have recommended MRI T2 for image guided brachytherapy. Recently, a new applicator (Benidorm Template, TB) has been developed in our Department (Rodriguez et al 2015). TB is fully MRI compatible because the Titanium needles and it allows the use of intrauterine tandem. Currently, TPS applicators library are not currently available for non-rigid applicators in case of interstitial component as the TB.The purpose of this work is to present the development of a library for the TB, together with its use on a pre-planning technique. Both new goals allow a very efficient and exclusive T2 MRI based planning clinical TB implementation. Methods: The developed library has been implemented in Oncentra Brachytherapy TPS, version 4.3.0 (Elekta) and now is being implemented on Sagiplan v 2.0 TPS (Eckert&Ziegler BEBIG). To model the TB, free and open software named FreeCAD and MeshLab have been used. The reconstruction process is based on three inserted A-vitamin pellets together with the data provided by the free length. The implemented preplanning procedure is as follow: 1) A MRI T2 acquisition is performed with the template in place just with the vaginal cylinder (no uterine tube nor needles). 2) The CTV is drawn and the required needles are selected using a developed Java based application and 3) A post-implant MRI T2 is performed. Results: This library procedure has been successfully applied by now in 25 patients. In this work the use of the developed library will be illustrated with clinical examples. The preplanning procedure has been applied by now in 6 patients, having significant advantages: needle depth estimation, needle positions and number are optimized a priori, time saving, etc Conclusion: TB library and pre-plan techniques are feasible and very efficient and their use will be illustrated in this work.

  19. SU-F-T-47: MRI T2 Exclusive Based Planning Using the Endocavitary/interstitial Gynecological Benidorm Applicator: A Proposed TPS Library and Preplan Efficient Methodology

    International Nuclear Information System (INIS)

    Richart, J; Otal, A; Rodriguez, S; Santos, M; Perez-Calatayud, J

    2016-01-01

    Purpose: ABS and GEC-ESTRO have recommended MRI T2 for image guided brachytherapy. Recently, a new applicator (Benidorm Template, TB) has been developed in our Department (Rodriguez et al 2015). TB is fully MRI compatible because the Titanium needles and it allows the use of intrauterine tandem. Currently, TPS applicators library are not currently available for non-rigid applicators in case of interstitial component as the TB.The purpose of this work is to present the development of a library for the TB, together with its use on a pre-planning technique. Both new goals allow a very efficient and exclusive T2 MRI based planning clinical TB implementation. Methods: The developed library has been implemented in Oncentra Brachytherapy TPS, version 4.3.0 (Elekta) and now is being implemented on Sagiplan v 2.0 TPS (Eckert&Ziegler BEBIG). To model the TB, free and open software named FreeCAD and MeshLab have been used. The reconstruction process is based on three inserted A-vitamin pellets together with the data provided by the free length. The implemented preplanning procedure is as follow: 1) A MRI T2 acquisition is performed with the template in place just with the vaginal cylinder (no uterine tube nor needles). 2) The CTV is drawn and the required needles are selected using a developed Java based application and 3) A post-implant MRI T2 is performed. Results: This library procedure has been successfully applied by now in 25 patients. In this work the use of the developed library will be illustrated with clinical examples. The preplanning procedure has been applied by now in 6 patients, having significant advantages: needle depth estimation, needle positions and number are optimized a priori, time saving, etc Conclusion: TB library and pre-plan techniques are feasible and very efficient and their use will be illustrated in this work.

  20. Adoption of Library 2.0 Functionalities by Academic Libraries and Users: A Knowledge Management Perspective

    Science.gov (United States)

    Kim, Yong-Mi; Abbas, June

    2010-01-01

    This study investigates the adoption of Library 2.0 functionalities by academic libraries and users through a knowledge management perspective. Based on randomly selected 230 academic library Web sites and 184 users, the authors found RSS and blogs are widely adopted by academic libraries while users widely utilized the bookmark function.…

  1. Establishing a PWR burn-up library

    International Nuclear Information System (INIS)

    Lutz, D.C.

    1981-01-01

    Starting out from data file ENDF/B IV /1/, a cross-section library has been established for the calculation of operating conditions in pressurized water reactors of the type used in BIBLIS B. The library includes macroscopic, homogenized 2-group cross-sections for all types of fuel elements used in this reactor, including those equipped with boron glass rods. For their calculation the previous irradiation of the fuel has been taken into consideration by approximation. Information on fuel consumption from cell burn-up calculations has been stored in a separate data file. It was designed as a base for the determination of cross sections to be used in the calculation of the incident ''main-steam pipe fracture''. For this library the description of cross sections as a function of the moderator status chose the water densities at 300 0 C/155 bar, 190 0 C/140 bar and 100 0 C/100 bar as fixed values. The burn-up library has been tested by a three-dimensional calculation for the 1sup(st) cycle of the BIBLIS B-reactor using program QUABOX /2/. This showed variances with the anticipated course concerning critically, which can be explained almost quantitatively by known deficiencies of the ENDF/b-IV library. (orig.) [de

  2. Individual-based and group-based occupational exposure assessment: some equations to evaluate different strategies.

    NARCIS (Netherlands)

    Tielemans, E.; Kupper, L.L.; Kromhout, H.; Heederik, D.; Houba, R.

    1998-01-01

    Basically, two strategies can be considered for the analysis of hazardous pollutants in the work environment: group-based and individual-based strategies. This paper provides existing and recently derived equations for both strategies describing the influence of several factors on attenuation and on

  3. SketchyDynamics: A Library for the Development of Physics Simulation Applications with Sketch-Based Interfaces

    Directory of Open Access Journals (Sweden)

    Abílio Costa

    2013-09-01

    Full Text Available Sketch-based interfaces provide a powerful, natural and intuitive way for users to interact with an application. By combining a sketch-based interface with a physically simulated environment, an application offers the means for users to rapidly sketch a set of objects, like if they are doing it on piece of paper, and see how these objects behave in a simulation. In this paper we present SketchyDynamics, a library that intends to facilitate the creation of applications by rapidly providing them a sketch-based interface and physics simulation capabilities. SketchyDynamics was designed to be versatile and customizable but also simple. In fact, a simple application where the user draws objects and they are immediately simulated, colliding with each other and reacting to the specified physical forces, can be created with only 3 lines of code. In order to validate SketchyDynamics design choices, we also present some details of the usability evaluation that was conducted with a proof-of-concept prototype

  4. MARKETING LIBRARY SERVICES IN ACADEMIC LIBRARIES: A ...

    African Journals Online (AJOL)

    MARKETING LIBRARY SERVICES IN ACADEMIC LIBRARIES: A TOOL FOR SURVIVAL IN THE ... This article discusses the concept of marketing library and information services as an ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  5. Scaffold architecture and pharmacophoric properties of natural products and trade drugs: application in the design of natural product-based combinatorial libraries.

    Science.gov (United States)

    Lee, M L; Schneider, G

    2001-01-01

    Natural products were analyzed to determine whether they contain appealing novel scaffold architectures for potential use in combinatorial chemistry. Ring systems were extracted and clustered on the basis of structural similarity. Several such potential scaffolds for combinatorial chemistry were identified that are not present in current trade drugs. For one of these scaffolds a virtual combinatorial library was generated. Pharmacophoric properties of natural products, trade drugs, and the virtual combinatorial library were assessed using a self-organizing map. Obviously, current trade drugs and natural products have several topological pharmacophore patterns in common. These features can be systematically explored with selected combinatorial libraries based on a combination of natural product-derived and synthetic molecular building blocks.

  6. Using Participatory and Service Design to Identify Emerging Needs and Perceptions of Library Services among Science and Engineering Researchers Based at a Satellite Campus

    Science.gov (United States)

    Johnson, Andrew; Kuglitsch, Rebecca; Bresnahan, Megan

    2015-01-01

    This study used participatory and service design methods to identify emerging research needs and existing perceptions of library services among science and engineering faculty, post-graduate, and graduate student researchers based at a satellite campus at the University of Colorado Boulder. These methods, and the results of the study, allowed us…

  7. The enhancement of simulation based learning exercises through formalised reflection, focus groups and group presentation

    NARCIS (Netherlands)

    Mawdesley, M.; Long, G.; Al-Jibouri, Saad H.S.; Scott, D.

    2011-01-01

    Computer based simulations and games can be useful tools in teaching aspects of construction project management that are not easily transmitted through traditional lecture based approaches. However, it can be difficult to quantify their utility and it is essential to ensure that students are

  8. A secure quantum group signature scheme based on Bell states

    International Nuclear Information System (INIS)

    Zhang Kejia; Song Tingting; Zuo Huijuan; Zhang Weiwei

    2013-01-01

    In this paper, we propose a new secure quantum group signature with Bell states, which may have applications in e-payment system, e-government, e-business, etc. Compared with the recent quantum group signature protocols, our scheme is focused on the most general situation in practice, i.e. only the arbitrator is trusted and no intermediate information needs to be stored in the signing phase to ensure the security. Furthermore, our scheme has achieved all the characteristics of group signature—anonymity, verifiability, traceability, unforgetability and undeniability, by using some current developed quantum and classical technologies. Finally, a feasible security analysis model for quantum group signature is presented. (paper)

  9. Strategic marketing planning in library

    Directory of Open Access Journals (Sweden)

    Karmen Štular-Sotošek

    2000-01-01

    Full Text Available The article is based on the idea that every library can design instruments for creating events and managing the important resources of today's world, especially to manage the changes. This process can only be successful if libraries use adequate marketing methods. Strategic marketing planning starts with the analysis of library's mission, its objectives, goals and corporate culture. By analysing the public environment, the competitive environment and the macro environment, libraries recognise their opportunities and threats. These analyses are the foundations for library definitions: What does the library represent?, What does it aspire to? Which goals does it want to reach? What kind of marketing strategy will it use for its target market?

  10. The communication of "pure" group-based anger reduces tendencies toward intergroup conflict because it increases out-group empathy.

    Science.gov (United States)

    de Vos, Bart; van Zomeren, Martijn; Gordijn, Ernestine H; Postmes, Tom

    2013-08-01

    The communication of group-based anger in intergroup conflict is often associated with destructive conflict behavior. However, we show that communicating group-based anger toward the out-group can evoke empathy and thus reduce intergroup conflict. This is because it stresses the value of maintaining a positive long-term intergroup relationship, thereby increasing understanding for the situation (in contrast to the communication of the closely related emotion of contempt). Three experiments demonstrate that the communication of group-based anger indeed reduces destructive conflict intentions compared with (a) a control condition (Experiments 1-2), (b) the communication of group-based contempt (Experiment 2), and (c) the communication of a combination of group-based anger and contempt (Experiments 2-3). Moreover, results from all three experiments reveal that empathy mediated the positive effect of communicating "pure" group-based anger. We discuss the implications of these findings for the theory and practice of communicating emotions in intergroup conflicts.

  11. Grouped to Achieve: Are There Benefits to Assigning Students to Heterogeneous Cooperative Learning Groups Based on Pre-Test Scores?

    Science.gov (United States)

    Werth, Arman Karl

    Cooperative learning has been one of the most widely used instructional practices around the world since the early 1980's. Small learning groups have been in existence since the beginning of the human race. These groups have grown in their variance and complexity overtime. Classrooms are getting more diverse every year and instructors need a way to take advantage of this diversity to improve learning. The purpose of this study was to see if heterogeneous cooperative learning groups based on student achievement can be used as a differentiated instructional strategy to increase students' ability to demonstrate knowledge of science concepts and ability to do engineering design. This study includes two different groups made up of two different middle school science classrooms of 25-30 students. These students were given an engineering design problem to solve within cooperative learning groups. One class was put into heterogeneous cooperative learning groups based on student's pre-test scores. The other class was grouped based on random assignment. The study measured the difference between each class's pre-post gains, student's responses to a group interaction form and interview questions addressing their perceptions of the makeup of their groups. The findings of the study were that there was no significant difference between learning gains for the treatment and comparison groups. There was a significant difference between the treatment and comparison groups in student perceptions of their group's ability to stay on task and manage their time efficiently. Both the comparison and treatment groups had a positive perception of the composition of their cooperative learning groups.

  12. THERMLIB, Generator and Edit of Program THERMOS-OTA Library. THERLIB, Library Generated for THERMOS from FACEL Library

    International Nuclear Information System (INIS)

    Rastas, A.

    1985-01-01

    1 - Description of problem or function: THERMLIB is a code that generates, revises and expands the input data library to the lattice cell code THERMOS-OTA. It can be used to: - create an entirely new library; - modify the data of library materials, remove materials, add materials; - list the library. 2 - Restrictions on the complexity of the problem: Max. of 30 materials may be modified or removed. Max. of 30 new materials may be created. Max. of 50 velocity groups

  13. Connection-based and object-based grouping in multiple-object tracking: A developmental study.

    Science.gov (United States)

    Van der Hallen, Ruth; Reusens, Julie; Evers, Kris; de-Wit, Lee; Wagemans, Johan

    2018-03-30

    Developmental research on Gestalt laws has previously revealed that, even as young as infancy, we are bound to group visual elements into unitary structures in accordance with a variety of organizational principles. Here, we focus on the developmental trajectory of both connection-based and object-based grouping, and investigate their impact on object formation in participants, aged 9-21 years old (N = 113), using a multiple-object tracking paradigm. Results reveal a main effect of both age and grouping type, indicating that 9- to 21-year-olds are sensitive to both connection-based and object-based grouping interference, and tracking ability increases with age. In addition to its importance for typical development, these results provide an informative baseline to understand clinical aberrations in this regard. Statement of contribution What is already known on this subject? The origin of the Gestalt principles is still an ongoing debate: Are they innate, learned over time, or both? Developmental research has revealed how each Gestalt principle has its own trajectory and unique relationship to visual experience. Both connectedness and object-based grouping play an important role in object formation during childhood. What does this study add? The study identifies how sensitivity to connectedness and object-based grouping evolves in individuals, aged 9-21 years old. Using multiple-object tracking, results reveal that the ability to track multiple objects increases with age. These results provide an informative baseline to understand clinical aberrations in different types of grouping. © 2018 The Authors. British Journal of Developmental Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society.

  14. The Impact Of Indigenous Community-Based Groups Towards ...

    African Journals Online (AJOL)

    access funding from government and/or other donors. Working in groups is indigenous to. African communities and has far-reaching effects, which reverberate beyond the boundaries of these groups and has historically been an embodiment of the way of life, custodian of customs, traditions and cultures and provide venue ...

  15. Training May Affect Primary Care Staff Access to the Biomedical Electronic Evidence Base. A review of: Doney, Liz, Helen Barlow, and Joe West. “Use of Libraries and Electronic Information Resources by Primary Care Staff: Outcomes from a Survey.” Health Information and Libraries Journal 22.3 (September 2005: 182-188.

    Directory of Open Access Journals (Sweden)

    Marcy L. Brown

    2006-03-01

    Full Text Available Objective – To assess use of existing local libraries, the Internet, and biomedical databases by primary care staff prior to implementation of the Primary Care Knowledge Management Projects. Additionally, to assess the need to train primary care staff to use the Internet and biomedical databases. Design – Cross‐sectional postal questionnaire survey. Setting – Nottingham and Rotherham, two cities in the Trent region of the UK. Subjects – Questionnaires were analyzed from 243 general practitioners, practice nurses, and practice managers in four Nottingham primary care trusts as well as practices in the Rotherham Health Authority area. Methods – Questionnaires and cover letters were sent between May 2001 and February 2002. To encourage response, a postage‐paid envelope was enclosed. A total of 709 questionnaires were sent in Nottingham, and 169 were returned for a response rate of 24%. In Rotherham, 179 questionnaires were sent and 61 returned, for a 34% response rate. Thirteen responses from a May 2001 pilot in Rotherham were also included in the data analysis. Survey questions included a variety of formats, including tick boxes and open‐ended questions. Data was entered into an Access database and analysis was performed using Stata software. Main results – Reported use of libraries was low overall, with only 30% of respondents claiming to have used library facilities. However, there was significant variation among professional groups. Practice nurses (PNs had significantly higher usage of libraries than general practitioners (GPs and practice managers (P Conclusion – Based on the results of this admittedly small study, additional training is needed – and desired – by primary care staff in both Nottingham and Rotherham. Developing and offering training in Internet searching and evaluation as well as use of the biomedical databases is one important way in which libraries can build partnerships with primary care practitioners

  16. Photon and decay data libraries for ORIGEN2 code based on JENDL FP decay data file 2000

    CERN Document Server

    Katakura, J I

    2002-01-01

    Photon and decay data libraries for the ORIGEN2 code have been updated by using JENDL FP Decay Data File 2000 (JENDL/FPD-00). As for the decay data, half-lives, branching ratios and recoverable energy values have been replaced with those of the JENDL/FPD-00 file. The data of the photon library has been also replaced with those of the JENDL/FPD-00 file in which photon data of the nuclides without measured data are calculated with a theoretical method. Using the updated photon library, the calculation of photon spectrum at a short time after fission event is able to be made.

  17. Using Analytics to Transform a Problem-Based Case Library: An Educational Design Research Approach

    Science.gov (United States)

    Schmidt, Matthew; Tawfik, Andrew A.

    2018-01-01

    This article describes the iterative design, development, and evaluation of a case-based learning environment focusing on an ill-structured sales management problem. We discuss our processes and situate them within the broader framework of educational design research. The learning environment evolved over the course of three design phases. A…

  18. Potential for DNA-based ID of Great Lakes fauna: Species inventories vs. barcode libraries

    Science.gov (United States)

    DNA-based identification of mixed-organism samples offers the potential to greatly reduce the need for resource-intensive morphological identification, which would be of value both to biotic condition assessment and non-native species early-detection monitoring. However the abil...

  19. Connecting Learning: Brain-Based Strategies for Linking Prior Knowledge in the Library Media Center

    Science.gov (United States)

    Vanderbilt, Kathi L.

    2005-01-01

    The brain is a complex organ and learning is a complex process. While there is not complete agreement among researchers about brain-based learning and its direct connection to neuroscience, knowledge about the brain as well as the examination of cognitive psychology, anthropology, professional experience, and educational research can provide…

  20. Library news

    CERN Multimedia

    CERN Library

    2010-01-01

    The CERN Library has been providing electronic access to the "Techniques de l'Ingénieur" database for the past 8 months. As a reminder, this is a multidisciplinary database of over 4000 technical and scientific articles in French, covering a broad range of topics such as mechanical engineering, safety, electronics and the environment. In a few simple steps, you can create your own account, select the types of documents you are interested in and configure your settings so as to receive alerts when articles in your field of activity are published. You can now access this resource from outside CERN using the "remote access to electronic resources" service. Further information is available here. Direct access to the database. Remote access to electronic resources. If you have any questions or comments, don't hesitate to contact us at: library.desk@cern.ch.

  1. The Weakest Link: Library Catalogs.

    Science.gov (United States)

    Young, Terrence E., Jr.

    2002-01-01

    Describes methods of correcting MARC records in online public access catalogs in school libraries. Highlights include in-house methods; professional resources; conforming to library cataloging standards; vendor services, including Web-based services; software specifically developed for record cleanup; and outsourcing. (LRW)

  2. How green in our library?

    OpenAIRE

    Horsfall, JM; Pitt, K

    2010-01-01

    An environment group has had a presence within Leeds Met Libraries since December 2004. Initially the group chose to look at simple things which could have a positive impact on how we use resources in the workplace. We introduced recycling bins for plastic cups and cans in the staff tearooms, provided dispensers for plastic carrier bags near the self-service machines and arranged training hours for library staff to learn more about environmental issues and to look at their carbon footprint. I...

  3. Library Benchmarking

    Directory of Open Access Journals (Sweden)

    Wiji Suwarno

    2017-02-01

    Full Text Available The term benchmarking has been encountered in the implementation of total quality (TQM or in Indonesian termed holistic quality management because benchmarking is a tool to look for ideas or learn from the library. Benchmarking is a processof measuring and comparing for continuous business process of systematic and continuous measurement, the process of measuring and comparing for continuous business process of an organization to get information that can help these organization improve their performance efforts.

  4. Polydiphenylacetylene with Schiff Base End Groups: Synthesis and Characterization

    Science.gov (United States)

    Kalinova, Radostina; Jossifov, Christo

    The carbonyl-olefin exchange reaction is a new reaction between carbonyl group and olefin double bond, which has a formal similarity with the olefin metathesis - one carbon atom in the latter is replaced with an oxygen atom. Till now the new reaction is performed successfully only when the two functional groups (carbonyl group and olefin double bond) are in one molecule and are conjugated. The α, β-unsaturated carbonyl compounds (substituted propenones) are the compounds with such a structure. They polymerize giving substituted polyacetylenes. The chain propagation step of this polymerization is in fact the carbonyl-olefin exchange reaction. The question arises: is it possible the carbonyl-olefin exchange reaction to take place when the two functional groups are not in one molecule and are not conjugated, and could this reaction become an alternative of the existing carbonyl olefination reactions?

  5. How to benchmark methods for structure-based virtual screening of large compound libraries.

    Science.gov (United States)

    Christofferson, Andrew J; Huang, Niu

    2012-01-01

    Structure-based virtual screening is a useful computational technique for ligand discovery. To systematically evaluate different docking approaches, it is important to have a consistent benchmarking protocol that is both relevant and unbiased. Here, we describe the designing of a benchmarking data set for docking screen assessment, a standard docking screening process, and the analysis and presentation of the enrichment of annotated ligands among a background decoy database.

  6. WIMS Library updating

    International Nuclear Information System (INIS)

    Ravnik, M.; Trkov, A.; Holubar, A.

    1992-01-01

    At the end of 1990 the WIMS Library Update Project (WLUP) has been initiated at the International Atomic Energy Agency. The project was organized as an international research project, coordinated at the J. Stefan Institute. Up to now, 22 laboratories from 19 countries joined the project. Phase 1 of the project, which included WIMS input optimization for five experimental benchmark lattices, has been completed. The work presented in this paper describes also the results of Phase 2 of the Project, in which the cross sections based on ENDF/B-IV evaluated nuclear data library have been processed. (author) [sl

  7. School Library Nostalgias

    Science.gov (United States)

    Hochman, Jessica

    2016-01-01

    This paper explores nostalgia as both a limiting cultural force in the lives of school librarians and a practice that can be used to more accurately portray library work. The stereotype of the shushing, lone school librarian, based on restorative nostalgia, is related to a nostalgic oversimplification of the school librarian's historical role.…

  8. Library Budget Primer.

    Science.gov (United States)

    Warner, Alice Sizer

    1993-01-01

    Discusses the advantages and disadvantages of six types of budgets commonly used by many different kinds of libraries. The budget types covered are lump-sum; formula; line or line-item; program; performance or function; and zero-based. Accompanying figures demonstrate the differences between four of the budget types. (three references) (KRN)

  9. Molecular Pathogenesis of Rickettsioses and Development of Novel Anti-Rickettsial Treatment by Combinatorial Peptide-Based Libraries

    National Research Council Canada - National Science Library

    Walker, David H; Olano, Juan P

    2007-01-01

    ...) library and challenge with R. prowazekii, R. rickettsii, and O. tsutsugamushi; 2) To determine the role of NF-kB, cytokines, ROS and NO in intracellular killing of rickettsia-infected monolayers containing adapteins and 3...

  10. Molecular Pathogenesis of Rickettsioses and Development of Novel Anti-Rickettsia Treatment by Comginatorial Peptide-Based Libraries

    National Research Council Canada - National Science Library

    Walker, David H; Olano, Juan P

    2005-01-01

    ...) library and challenge with R. prowazekii, R. rickettsii, and 0. tsutsugamushi; 2) To determine the role of NF-KB, cytokines, ROS and NO in intracellular killing of rickettsia-infected monolayers containing adapteins and 3...

  11. PR01 Molecular Pathogenesis of Rickettsioses and Development of Anti-Rickettsial Treatment by Combinatorial Peptide-Based Libraries

    National Research Council Canada - National Science Library

    Walker, David H

    2006-01-01

    ...) library and challenge with R. prowazekii, R. rickettsii, and O. tsutsugamushi; 2) To determine the role of NF-kB, cytokines, ROS and NO in intracellular killing of rickettsia-infected monolayers containing adapteins and 3...

  12. PR01 Molecular Pathogenesis of Rickettsioses and Development of Anti-Rickettsial Treatment by Combinatorial Peptide-Based Libraries

    National Research Council Canada - National Science Library

    Walker, David H

    2006-01-01

    The purpose of this study is to utilize adaptein libraries coded within pantropic retroviral vectors that confer protection against rickettsial pathogens and to study the molecular pathogenesis of rickettsioses...

  13. Positive Correlation Between Academic Library Services and High-Impact Practices for

    Directory of Open Access Journals (Sweden)

    Saori Wendy Herman, MLIS, AHIP

    2016-03-01

    Full Text Available Objective – To investigate the perceived alignment between academic library services and high-impact practices (HIPs that affect student retention. Design – Survey questionnaire. Setting – Public comprehensive universities in the United States of America with a Carnegie classification of master’s level as of January 2013. Subjects – 68 library deans or directors out of the 271 who were originally contacted. Methods – The author used Qualtrics software to create a survey based on the HIPs, tested the survey for reliability, and then distributed it to 271 universities. Library services were grouped into 1 of 3 library scales: library collection, library instruction, or library facilities. The survey consisted of a matrix of 10 Likert-style questions addressing the perceived level of alignment between the library scales and the HIPs. Each question provided an opportunity for the respondent to enter a “brief description of support practices” (p 477. Additional demographic questions addressed the years of experience of the respondent, undergraduate student enrollment of the university, and whether librarians held faculty rank. Main Results – The author measured Pearson correlation coefficients and found a positive correlation between the library scales and the HIPs. All three library scales displayed a moderately strong positive correlation between first-year seminars and experiences (HIP 1, common intellectual experiences (HIP 2, writing-intensive courses (HIP 4, undergraduate research (HIP 6, diversity and global learning (HIP 7, service learning and community-based learning (HIP 8, internships (HIP 9, and capstone courses and projects (HIP 10. The library collections scale and library facilities scale displayed a moderately strong correlation with learning communities (HIP 3 and collaborative assignments and projects (HIP 5. The library instruction scale displayed a strong positive correlation with HIP 3 and a very strong

  14. Validation of Fully Automated VMAT Plan Generation for Library-Based Plan-of-the-Day Cervical Cancer Radiotherapy

    OpenAIRE

    Sharfo, Abdul Wahab M.; Breedveld, Sebastiaan; Voet, Peter W. J.; Heijkoop, Sabrina T.; Mens, Jan-Willem M.; Hoogeman, Mischa S.; Heijmen, Ben J. M.

    2016-01-01

    textabstractPurpose: To develop and validate fully automated generation of VMAT plan-libraries for plan-of-the-day adaptive radiotherapy in locally-advanced cervical cancer. Material and Methods: Our framework for fully automated treatment plan generation (Erasmus-iCycle) was adapted to create dual-arc VMAT treatment plan libraries for cervical cancer patients. For each of 34 patients, automatically generated VMAT plans (autoVMAT) were compared to manually generated, clinically delivered 9-be...

  15. A model-based approach to operational event groups ranking

    Energy Technology Data Exchange (ETDEWEB)

    Simic, Zdenko [European Commission Joint Research Centre, Petten (Netherlands). Inst. for Energy and Transport; Maqua, Michael [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Koeln (Germany); Wattrelos, Didier [Institut de Radioprotection et de Surete Nucleaire (IRSN), Fontenay-aux-Roses (France)

    2014-04-15

    The operational experience (OE) feedback provides improvements in all industrial activities. Identification of the most important and valuable groups of events within accumulated experience is important in order to focus on a detailed investigation of events. The paper describes the new ranking method and compares it with three others. Methods have been described and applied to OE events utilised by nuclear power plants in France and Germany for twenty years. The results show that different ranking methods only roughly agree on which of the event groups are the most important ones. In the new ranking method the analytical hierarchy process is applied in order to assure consistent and comprehensive weighting determination for ranking indexes. The proposed method allows a transparent and flexible event groups ranking and identification of the most important OE for further more detailed investigation in order to complete the feedback. (orig.)

  16. Personality traits and group-based information behaviour

    DEFF Research Database (Denmark)

    Hyldegård, Jette

    2009-01-01

    followed during a project assignment. The long version of the commonly-used NEO-PI-R test instrument was employed to describe and compare each group member's personality traits at a more detailed level. Data were also collected through a process survey, a diary and an interview. Analysis. The calculation....... Information behaviour associated with personality traits was identified, but the presence of personality effects tended to vary with the perceived presence of the social context. Conclusions. Some matches were identified between group members' personality traits and their actual information behaviour...... but there were also deviations, which were found that seemed to be related to the group-work context. The importance of studying personality traits in context has further been confirmed....

  17. Clebsch-Gordan coefficients of discrete groups in subgroup bases

    Science.gov (United States)

    Chen, Gaoli

    2018-04-01

    We express each Clebsch-Gordan (CG) coefficient of a discrete group as a product of a CG coefficient of its subgroup and a factor, which we call an embedding factor. With an appropriate definition, such factors are fixed up to phase ambiguities. Particularly, they are invariant under basis transformations of irreducible representations of both the group and its subgroup. We then impose on the embedding factors constraints, which relate them to their counterparts under complex conjugate and therefore restrict the phases of embedding factors. In some cases, the phase ambiguities are reduced to sign ambiguities. We describe the procedure of obtaining embedding factors and then calculate CG coefficients of the group 𝒫𝒮ℒ2(7) in terms of embedding factors of its subgroups S4 and 𝒯7.

  18. High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses.

    Directory of Open Access Journals (Sweden)

    Rajini Mudhasani

    2014-08-01

    Full Text Available High content image-based screening was developed as an approach to test a protease inhibitor small molecule library for antiviral activity against Rift Valley fever virus (RVFV and to determine their mechanism of action. RVFV is the causative agent of severe disease of humans and animals throughout Africa and the Arabian Peninsula. Of the 849 compounds screened, 34 compounds exhibited ≥ 50% inhibition against RVFV. All of the hit compounds could be classified into 4 distinct groups based on their unique chemical backbone. Some of the compounds also showed broad antiviral activity against several highly pathogenic RNA viruses including Ebola, Marburg, Venezuela equine encephalitis, and Lassa viruses. Four hit compounds (C795-0925, D011-2120, F694-1532 and G202-0362, which were most active against RVFV and showed broad-spectrum antiviral activity, were selected for further evaluation for their cytotoxicity, dose response profile, and mode of action using classical virological methods and high-content imaging analysis. Time-of-addition assays in RVFV infections suggested that D011-2120 and G202-0362 targeted virus egress, while C795-0925 and F694-1532 inhibited virus replication. We showed that D011-2120 exhibited its antiviral effects by blocking microtubule polymerization, thereby disrupting the Golgi complex and inhibiting viral trafficking to the plasma membrane during virus egress. While G202-0362 also affected virus egress, it appears to do so by a different mechanism, namely by blocking virus budding from the trans Golgi. F694-1532 inhibited viral replication, but also appeared to inhibit overall cellular gene expression. However, G202-0362 and C795-0925 did not alter any of the morphological features that we examined and thus may prove to be good candidates for antiviral drug development. Overall this work demonstrates that high-content image analysis can be used to screen chemical libraries for new antivirals and to determine their

  19. Roles of the Amino Group of Purine Bases in the Thermodynamic Stability of DNA Base Pairing

    Directory of Open Access Journals (Sweden)

    Shu-ichi Nakano

    2014-08-01

    Full Text Available The energetic aspects of hydrogen-bonded base-pair interactions are important for the design of functional nucleotide analogs and for practical applications of oligonucleotides. The present study investigated the contribution of the 2-amino group of DNA purine bases to the thermodynamic stability of oligonucleotide duplexes under different salt and solvent conditions, using 2'-deoxyriboinosine (I and 2'-deoxyribo-2,6-diaminopurine (D as non-canonical nucleotides. The stability of DNA duplexes was changed by substitution of a single base pair in the following order: G•C > D•T ≈ I•C > A•T > G•T > I•T. The apparent stabilization energy due to the presence of the 2-amino group of G and D varied depending on the salt concentration, and decreased in the water-ethanol mixed solvent. The effects of salt concentration on the thermodynamics of DNA duplexes were found to be partially sequence-dependent, and the 2-amino group of the purine bases might have an influence on the binding of ions to DNA through the formation of a stable base-paired structure. Our results also showed that physiological salt conditions were energetically favorable for complementary base recognition, and conversely, low salt concentration media and ethanol-containing solvents were effective for low stringency oligonucleotide hybridization, in the context of conditions employed in this study.

  20. Object-Oriented Technology-Based Software Library for Operations of Water Reclamation Centers

    Science.gov (United States)

    Otani, Tetsuo; Shimada, Takehiro; Yoshida, Norio; Abe, Wataru

    SCADA systems in water reclamation centers have been constructed based on hardware and software that each manufacturer produced according to their design. Even though this approach used to be effective to realize real-time and reliable execution, it is an obstacle to cost reduction about system construction and maintenance. A promising solution to address the problem is to set specifications that can be used commonly. In terms of software, information model approach has been adopted in SCADA systems in other field, such as telecommunications and power systems. An information model is a piece of software specification that describes a physical or logical object to be monitored. In this paper, we propose information models for operations of water reclamation centers, which have not ever existed. In addition, we show the feasibility of the information model in terms of common use and processing performance.