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Sample records for graps kurdab vsimust

  1. Elisa Studio showroom = Elisa Studio showroom / Jan Joonas Graps ; kommenteerinud Tiina Kuusisto

    Index Scriptorium Estoniae

    Graps, Jan Joonas, 1972-

    2015-01-01

    Elisa Studio showroom Helsingis Lasiplatsi, Mannerheimintie 22-24. Sisekujunduse autorid Jan Joonas Graps, Ken-Kristjan Ruut, Anne Määrmann (JanKen Wisespace). Lühidalt loovstuudiost JanKen Wisespace

  2. miR-654-5p Targets GRAP to Promote Proliferation, Metastasis, and Chemoresistance of Oral Squamous Cell Carcinoma Through Ras/MAPK Signaling.

    Science.gov (United States)

    Lu, Meng; Wang, Chengyong; Chen, Weihui; Mao, Chuanqing; Wang, Jin

    2018-04-01

    Oral squamous cell carcinoma (OSCC) is characterized by rapid local migration and invasion. This study was aimed at clarifying the effect of miR-654-5p on progression of OSCC. miR-654-5p promoted proliferation, metastasis, and chemoresistance of OSCC in vitro and in vivo. Consistently, miR-654-5p was upregulated in late-stage OSCC and was correlated with poor prognosis of OSCC patients. Furthermore, miR-654-5p was mechanistically verified to target Grb-2-related adaptor protein (GRAP), accompanied by the activation of Ras/MAPK signaling and the facilitation of epithelial-mesenchymal transition in OSCC cells. GRAP was downregulated in T1-2 stage versus T3-4 stage head and neck squamous cell carcinoma (HNSC) and was negatively correlated with tumor-node-metastases (TNM) stage in HNSC patients based on The Cancer Genome Atlas (TCGA) analysis. In addition, GRAP was positively correlated with good prognosis in HNSC patients. Our findings suggest that the miR-654-5p/GRAP/Ras/Erk signaling pathway in OSCC cells might contribute to the underlying mechanism through which miR-654-5p participates in the regulation of OSCC progression. miR-654-5p, as a potential biomarker for the clinical diagnosis and prognosis of OSCC, may be an effective anticancer target for the treatment of OSCC.

  3. Vastuvooluteater, mainstream ja arengus toppama jäänud teater... või mis? / Margot Visnap

    Index Scriptorium Estoniae

    Visnap, Margot, 1959-

    2004-01-01

    Vastuseks artiklile Eesti Päevalehes (30. märts), kus Priit Raud kurdab eesti teatri isoleerituse üle. Ka muljeid M. Kõivu "Finis nihili" lavastusest, Saaremaa miniteatripäevadest, G. B. Shaw näidendi "Tagasi Metuusala juurde" 5. osa "Mõtte piiridele" etendusest ja J. Jacobsi ja W. Casey muusikalist "Grease"

  4. Iisraeli-Palestiina vastasseis : kahe tõe võitlus määrib mõlemad verega / Ivar Soopan

    Index Scriptorium Estoniae

    Soopan, Ivar, 1971-

    2007-01-01

    Iisraeli-Palestiina konflikt alates 1967. aastast. Vt. samas: Minister kurdab apartheidi. Palestiina teabeminister Mustafa Barghouti ütles intervjuus ajalehele Palestine Times, et vastasseis Iisraeliga laheneks, kui Iisrael tunnistaks, et palestiinlased ja iisraellased on võrdsed inimesed võrdsete õigustega ja neil peaksid olema võrdsed võimalused. Tema sõnul on okupatsioon loonud Palestiinas apartheidi

  5. Challenges with the financial reporting of biological assets by public entities in South Africa

    Directory of Open Access Journals (Sweden)

    Deon Scott

    2016-03-01

    Full Text Available Fair value accounting of biological assets in the public sector was introduced with the adoption of the public-sector-specific accounting standard: Generally Recognised Accounting Practice (GRAP 101. The public sector currently reports on various bases of accounting. Public entities and municipalities report in terms of accrual accounting, and government departments report on the modified cash basis. The lack of a uniform basis of accounting impedes the comparability of financial information. The implementation of GRAP 101 in the public sector is important in facilitating comparability of financial information regarding biological assets. This paper is based on a content analysis of the annual reports of 10 relevant public entities in South Africa and specifically details the challenges that public entities encounter with the application of GRAP 101. These challenges, and how they were addressed by a public entity that adopted and applied GRAP 101, namely the Accelerated and Shared Growth Initiative South Africa – Eastern Cape (AsgiSA-EC, are documented in this research.

  6. GRAP, Gamma-Ray Level-Scheme Assignment

    International Nuclear Information System (INIS)

    Franklyn, C.B.

    2002-01-01

    1 - Description of program or function: An interactive program for allocating gamma-rays to an energy level scheme. Procedure allows for searching for new candidate levels of the form: 1) L1 + G(A) + G(B) = L2; 2) G(A) + G(B) = G(C); 3) G(A) + G(B) = C (C is a user defined number); 4) L1 + G(A) + G(B) + G(C) = L2. Procedure indicates intensity balance of feed and decay of each energy level. Provides for optimization of a level energy (and associated error). Overall procedure allows for pre-defining of certain gamma-rays as belonging to particular regions of the level scheme, for example, high energy transition levels, or due to beta- decay. 2 - Method of solution: Search for cases in which the energy difference between two energy levels is equal to a gamma-ray energy within user-defined limits. 3 - Restrictions on the complexity of the problem: Maximum number of gamma-rays: 999; Maximum gamma ray energy: 32000 units; Minimum gamma ray energy: 10 units; Maximum gamma-ray intensity: 32000 units; Minimum gamma-ray intensity: 0.001 units; Maximum number of levels: 255; Maximum level energy: 32000 units; Minimum level energy: 10 units; Maximum error on energy, intensity: 32 units; Minimum error on energy, intensity: 0.001 units; Maximum number of combinations: 6400 (ca); Maximum number of gamma-ray types : 127

  7. Interchangeable grabs for mobile cranes

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, A

    1985-02-07

    Not only the large variety of material to be handled, but also the enormous amounts of material to be loaded and unloaded have been a constant source of danger for the operators of mobile or portal cranes with cable pull, or of fork lifters. Bad accident statistics and materials handling problems have thus been the reason leading to the purchase of mobile cranes with stable load handling and, in the following, to the development of various graps suitable for the different types of material to be handled. Rigid graps with hydraulic drive and designed for mechanical replacement have been developed and tested. The following equipment has so far been tested and developed to maturity: Rapid replacement automatism, tipping and magnetic slewing mechanism, safety equipment for magnetic operation, vacuum lifter and stacker fork.

  8. Kodumaine ja nooruslik / Piret Veigel, Irene Roos

    Index Scriptorium Estoniae

    Veigel, Piret, 1961-

    2003-01-01

    Arhitekt Vahur Sova projekteeritud ökomaja eeskujul kujundatud elutuba. Värvivalik on inspireeritud looduse sügistalvistest toonidest ja naturaalsetest materjalidest. Stilistid Piret Veigel ja Irene Roos. Vineerkapi on kujundanud Tarmo Luisk, laua Jan J. Graps, sirmi Igor Volkov

  9. Toward good read-across practice (GRAP) guidance

    NARCIS (Netherlands)

    Ball, N.; Cronin, M.T.D.; Shen, J.; Blackburn, K.; Booth, E.D.; Bouhifd, M.; Donley, E.; Egnash, L.; Hastings, C.; Juberg, D.R.; Kleensang, A.; Kleinstreuer, N.; Kroese, E.D.; Lee, A.C.; Luechtefeld, T.; Maertens, A.; Marty, S.; Naciff, J.M.; Palmer, J.; Pamies, D.; Penman, M.; Richarz, A.N.; Russo, D.P.; Stuard, S.B.; Patlewicz, G.; Ravenzwaay, B. van; Wu, S.; Zhu, H.; Hartung, T.

    2016-01-01

    Grouping of substances and utilizing read-across of data within those groups represents an important data gap filling technique for chemical safety assessments. Categories/analogue groups are typically developed based on structural similarity and, increasingly often, also on mechanistic (biological)

  10. OÜ Jungent bürooruumid Tallinnas : Paldiski mnt. 11 = Jungent office space : Paldiski mnt. 11, Tallinn / Epp Lankots

    Index Scriptorium Estoniae

    Lankots, Epp, 1976-

    2005-01-01

    Sisearhitektid Jan Joonas Graps ja Ken-Kristjan Ruut pälvisid OÜ Jungent bürooruumide jõulise ja mittekonventsionaalse sisekujunduse eest Eesti Kultuurkapitali arhitektuuri sihtkapitali 2004. a. sisekujunduspreemia. Ill.: 1 värv. välis- ja 5 sisevaadet

  11. Askeetlik ja põhjamaine mööbel / Aivo Vahemets

    Index Scriptorium Estoniae

    Vahemets, Aivo

    2005-01-01

    Eesti täispuidust disainmööbli sarjast Incognito. Toodab Pear Välile ja vendadele Jan J. Grapsile ning Ken K. Ruudule kuuluv Hea Ruum OÜ. Disainerid on Jan J. Graps ja Pear Väli, aksessuaaride disainiga töötab Kristi Jalakas

  12. Targa Maja kompetentsikeskus Rakveres = Smart House Competence Centre in Rakvere / Oliver Alver

    Index Scriptorium Estoniae

    Alver, Oliver, 1977-

    2016-01-01

    Targa Maja kompetentsikeskus Rakveres, Lai tänav 20. Arhitektid Oliver Alver, Andres Alver, Indrek Rünkla, Tarmo Laht, Ott Alver, Sven Koppel, Ulla Saar (Alver Arhitektid). Sisearhitektid Jan Graps, Ken Ruut, Anne Määrmann (Jan&Ken OÜ). Kultuurkapitali Arhitektuuri sihtkapitali aastapreemia nominent 2016

  13. Starmani teenindusbüroo = Starman customer service centre

    Index Scriptorium Estoniae

    2009-01-01

    Eesti Sisearhitektide Liidu 2008. a. ühiskondliku interjööri preemia pälvinud Starmani teenindusbüroost Tallinnas Rävala pst. 19. Sisearhitektid Jan Joonas Graps ja Ken-Kristjan Ruut (OÜ Jan & Ken). Sisearhitektide tähtsamate ühiselt tehtud tööde loetelu

  14. Disainiaasta eelmäng toimus Helsingis / Ave Randviir

    Index Scriptorium Estoniae

    Randviir, Ave, 1981-

    2006-01-01

    Eesti disaini tutvustav rändnäitus "10D" Helsingi disaini infokeskuses Design Forum Finland 23.08-10.09.2006. Osalevad Martin Pärn, Igor Volkov, Heikki Zoova, Tarmo Luisk, Raimo Sau, TEN TWELWE OÜ (Jukka Halttunen, Tommi Silvan), Jan Graps, Lasse Ira, Ivari Männi, Tõnis Vellama, Ilona Gurjanova

  15. Intimo diskreetne võlu / Ell-Maaja Randküla

    Index Scriptorium Estoniae

    Randküla, Ell-Maaja, 1939-2016

    2006-01-01

    Tallinnas Viru t. 17 asuva kaupluse Boutique Intimo sisekujundus. Sisearhitektid Jan Joonas Graps, Ken-Kristjan Ruut ja Ursula Sõber. J. J. Grapsist ja K.-K. Ruudust, nende tähtsamad tööd. Ill.: värv. foto J. J. Grapsist ja K.-K. Ruudust, plaan, 12 värv. vaadet

  16. Variação na qualidade do azeite em cultivares de oliveira

    Directory of Open Access Journals (Sweden)

    Luiz Fernando de Oliveira da Silva

    2012-01-01

    Full Text Available O cultivo de oliveira (Olea europaea L. no sul de Minas Gerais tem apresentado resultados promissores quanto à produção de frutos. No entanto, há necessidade de verificar seu valor nutritivo e a qualidade do azeite oriundo dos frutos das cultivares potencialmente produtivas. Objetivou-se com este trabalho determinar a composição centesimal dos frutos, as características químicas e o perfil de ácidos graxos dos azeites extraídos de diferentes cultivares de oliveira, com a finalidade de selecionar os materiais com potencial agroindustrial. Foram avaliadas 32 cultivares de oliveira com seis anos de idades quanto à composição centesimal (teores de umidade, lipídeos, proteínas e cinzas, tanto na polpa quanto no caroço dos frutos; composição química e perfil de ácidos graxos dos azeites. Observaram-se nas cultivares MGS ASC315, Cerignola, MGS GRAP561 e MGS GRAP575 maiores valores de lipídeos. Além disso, as análises indicaram que o caroço possui quantidades significativas de lipídeos, embora sempre inferiores às quantidades presentes na polpa. Os índices de acidez em ácido oleico, peróxidos e refração absoluta estão de acordo com a resolução da ANVISA, podendo ser inicialmente classificados como azeite de oliva extravirgem ou virgem. De modo geral, todos os ácidos graxos presentes nos azeites possuem valores satisfatórios, destacando a cultivar MGS GRAP084, com maior concentração de ácido oleico, principal ácido responsável pelos benefícios à saúde.

  17. Kontori ja klubimaailma sümbioos / Ell-Maaja Randküla

    Index Scriptorium Estoniae

    Randküla, Ell-Maaja, 1939-2016

    2005-01-01

    Büroohoone Jungent Tallinnas Paldiski mnt. 11. Sisekujundus: Jan Joonas Graps ja Ken-Kristjan Ruut, OÜ Jan & Ken. Pilgupüüdjaks büroos on ka Kaido Ole suureformaadilised maalid. K.-K. Ruudust ja J. J. Grapsist, nende tähtsamad tööd. Ill.: 3 plaani, 15 värv. vaadet

  18. Eesti disain taas Pariisis

    Index Scriptorium Estoniae

    2007-01-01

    Eesti Disainerite Liit esitleb septembris 2007 oma kollektsiooni Pariisi sisustusmessi Maison&Object disainisektsioonis NOW! Stendi kujundus on Anneli Lobjalt. Osalejatest nimetatud: Annike Laigo, Merike Rehepapp, Jaanus Orgusaar, Jan Graps, Ken Ruut, Jaakko Matsalu, Eva-Liisa Kriis, Liisa Kallam, Liisa Tomasberg, Tarmo Luisk, Monika Järg, Keret Altpere, Elna Kaasik, Tõnis Vellama ja Ilona Gurjanova

  19. Eesti arukas hotell St Etienneþi disainibiennaalil

    Index Scriptorium Estoniae

    2008-01-01

    2006. a. käivitus Eesti-Soome koostööprojekt "Estonian and Finnish Design Challenge". Koostöös ettevõtjatega sündis DesignStart programmi piloot "Smart Hotell", milles osalesid disainerid Tarmo Luisk, Ivari Männi, Monika Järg, Keret Altpere, Igor Volkov, Jan Graps, Ken Ruut, Jukka Halttunen, Tapio Anttila ja Ilona Gurjanova ning mis valiti St. Etienneþi disainibiennaali projektide hulka

  20. Use of a simplified consent form to facilitate patient understanding of informed consent for laparoscopic cholecystectomy

    OpenAIRE

    Borello Alessandro; Ferrarese Alessia; Passera Roberto; Surace Alessandra; Marola Silvia; Buccelli Claudio; Niola Massimo; Di Lorenzo Pierpaolo; Amato Maurizio; Di Domenico Lorenza; Solej Mario; Martino Valter

    2016-01-01

    Abstract Background Surgical informed consent forms can be complicated for patients to read and understand. We created a consent form with key information presented in bulleted texts and diagrams combined in a graphical format to facilitate the understanding of information during the verbal consent discussion. Methods This prospective, randomized study involved 70 adult patients awaiting cholecystectomy for gallstones. Consent was obtained after standard verbal explanation using either a grap...

  1. Grab for gripping open moulds and those closed with a lid with radioactive contents

    International Nuclear Information System (INIS)

    1981-01-01

    The grap consists of a through shaft at the top end of which the crane suspension is fastened. The lower shaft end carries a star-shaped sleeve, whose six arms have radial slots. Grab arms with grab claws alternatively directed inwards and outwards are assigned to the six arms of the sleeve. The grab arms can be actuated or held in the guides or switching curves in three different positions. (DG) [de

  2. CARACTERÍSTICAS DEMOGRÁFICAS, HÁBITOS DE VIDA E HISTORIA DEL CONSUMO DE TABACO DE LOS FUMADORES OCASIONALES EN ESPAÑA

    Directory of Open Access Journals (Sweden)

    Lucía Díez Gañán

    2002-01-01

    Full Text Available Back ground. This study des cribes the so cio de mo grap hic cha rac te ris tics, health-re lated li fest yle, and his tory of to bac co con sump tion of the oc casional smo kers in Spain, and exa mines whet her they show dif fe ren ces against daily smo kers. Met hods. Data were ob tai ned from the Na tional Health Sur vey of Spain, ca rried out in 1993 through hou sehold in ter - views on a sam ple re pre sen ta ti ve of the non-ins ti tu tio na li sed po pu la tion aged 16 year and ol der. Analy ses were per for med with lo gis tic re gres sion and ad justed for so cio de mo grap hic, health-sta te and life-style va ria bles. Results. Out of the 6,668 smo kers in the sur vey, oc casional smokers were 9.2%, whi le daily smo kers of £5 ci garettes and >5 cigarettes were 9.9% and 80.9%, res pectively. As com pared with daily smo kers of >5 ci garettes, oc casional smo kers were more fre - quently wo men (odds ra tio (0R:2.12; CI95%:1.72-2.61, youn ger (OR aged 25-44 ver sus 16-24 years: 0.75; 0.58-0.96, with lo wer alcohol con sumption (p for li near trend: 0.0349, and hig her lei su - re-time physi cal ac tivity (p for li near trend: 5 ci garettes. Con clu sions: Occa sio nal smo kers show so cio de mo grap hic cha rac te ris tics, health-re lated li fest yle, and his tory of to bac co con sump tion dif fe rent from daily smo kers. Such dif fe ren ces sug gest that re search and in ter ven tion pro grams spe cifically tai lo red to oc ca sio nal smo kers should be de veloped.

  3. Perceptions of visual communication design education in higher education in Ireland: A multi-case study from the design industry, institutes and graduates perspectives

    OpenAIRE

    DOWLING, FIONA

    2018-01-01

    APPROVED ?Use your own vision and mentality in order to form design decisions + Don?t believe your professor? Annelys de Vet ? (Kiosoglou & Frank, Ed. 2013., p 34). The aim of the study was to evaluate and construct an explanation behind the currency that higher education degrees in design enjoy in Ireland. The Visual Communication (VC) design discipline at Bachelors (BA) level accounted for the greatest cohort of students leaving design HE in Ireland in the 1990s. This grap...

  4. Graph Treewidth and Geometric Thickness Parameters

    OpenAIRE

    Dujmović, Vida; Wood, David R.

    2005-01-01

    Consider a drawing of a graph $G$ in the plane such that crossing edges are coloured differently. The minimum number of colours, taken over all drawings of $G$, is the classical graph parameter "thickness". By restricting the edges to be straight, we obtain the "geometric thickness". By further restricting the vertices to be in convex position, we obtain the "book thickness". This paper studies the relationship between these parameters and treewidth. Our first main result states that for grap...

  5. Kultuurkapitali aastapreemiad 2004 / Sverre Laanjärv

    Index Scriptorium Estoniae

    Laanjärv, Sverre

    2005-01-01

    Eesti Kultuurkapitali peapreemia sai Toomas Rank Rägavere mõisa ennistamise eest. Arhitektuuri sihtkapitali renoveerimispreemia - Mari Kurismaa, Eesti Draamateatri interjööride renoveerimine; objektipreemia - Martin Aunin, Ülemiste hotell; interjööripreemia - Jan Joonas Graps, Ken-Kristjan Ruut, "Jungenti" büroo; arhitektuurse tegevuse preemia - Veneetsia biennaali Eesti väljapaneku "Time Out Architecture" autorid (Kristjan Holm ning Liina Jänes, Agu Külm, Jukka-Pekka Jalovaara, Pille Epner, Madis Jürgen, Tõnu Kaalep, Ingmar Muusikus)

  6. Arhitektuuriaasta 2004 = The year in architecture 2004 / Epp Lankots

    Index Scriptorium Estoniae

    Lankots, Epp, 1976-

    2005-01-01

    Arhitektuuriauhindade nominentidest ja premeeritutest. Eesti Kultuurkapitali aastapreemia sai Toomas Rank Rägavere mõisa renoveerimise eest. Arhitektuuri sihtkapitali renoveerimispreemia - Mari Kurismaa, Eesti Draamateatri interjööride renoveerimine; objektipreemia - Martin Aunin, Ülemiste hotell; interjööripreemia - Jan Joonas Graps, Ken-Kristjan Ruut, "Jungenti" büroo; arhitektuurse tegevuse preemia - Kristjan Holm, Liina Jänes, Agu Külm, Jukka-Pekka Jalovaara, Pille Epner, Madis Jürgen, Tõnu Kaalep, Ingmar Muusikus, Eesti ekspositsioon "Aeg-maha-arhitektuur" Veneetsia arhitektuuribiennaalil

  7. Towards functionalization of graphene: in situ study of the nucleation of copper-phtalocyanine on graphene

    OpenAIRE

    Schwarz, Daniel; Henneke, Caroline; Kumpf, Christian

    2016-01-01

    Molecular films present an elegant way for the uniform functionalization or doping of graphene. Here, we present an in situ study on the initial growth of copper phthalocyanine (CuPc) on epitaxial graphene on Ir(111). We followed the growth up to a closed monolayer with low energy electron microscopy and selected area electron diffraction (μLEED). The molecules coexist on graphene in a disordered phase without long-range order and an ordered crystalline phase. The local topography of the grap...

  8. Introductory graph theory

    CERN Document Server

    Chartrand, Gary

    1984-01-01

    Graph theory is used today in the physical sciences, social sciences, computer science, and other areas. Introductory Graph Theory presents a nontechnical introduction to this exciting field in a clear, lively, and informative style. Author Gary Chartrand covers the important elementary topics of graph theory and its applications. In addition, he presents a large variety of proofs designed to strengthen mathematical techniques and offers challenging opportunities to have fun with mathematics. Ten major topics - profusely illustrated - include: Mathematical Models, Elementary Concepts of Grap

  9. Unveiling the Structural Origin of the High Carrier Mobility of a Molecular Monolayer on Boron Nitride

    OpenAIRE

    Xu, Rui; He, Daowei; Zhang, Yuhan; Wu, Bing; Liu, Fengyuan; Meng, Lan; Liu, Jun-Fang; Wu, Qisheng; Shi, Yi; Wang, Jinlan; Nie, Jia-Cai; Wang, Xinran; He, Lin

    2014-01-01

    Very recently, it was demonstrated that the carrier mobility of a molecular monolayer dioctylbenzothienobenzothiophene (C8-BTBT) on boron nitride can reach 10 cm2/Vs, the highest among the previously reported monolayer molecular field-effect transistors. Here we show that the high-quality single crystal of the C8-BTBT monolayer may be the key origin of the record-high carrier mobility. We discover that the C8-BTBT molecules prefer layer-by-layer growth on both hexagonal boron nitride and grap...

  10. Mathematical structures for computer graphics

    CERN Document Server

    Janke, Steven J

    2014-01-01

    A comprehensive exploration of the mathematics behind the modeling and rendering of computer graphics scenes Mathematical Structures for Computer Graphics presents an accessible and intuitive approach to the mathematical ideas and techniques necessary for two- and three-dimensional computer graphics. Focusing on the significant mathematical results, the book establishes key algorithms used to build complex graphics scenes. Written for readers with various levels of mathematical background, the book develops a solid foundation for graphics techniques and fills in relevant grap

  11. Weighted Maximum-Clique Transversal Sets of Graphs

    OpenAIRE

    Chuan-Min Lee

    2011-01-01

    A maximum-clique transversal set of a graph G is a subset of vertices intersecting all maximum cliques of G. The maximum-clique transversal set problem is to find a maximum-clique transversal set of G of minimum cardinality. Motivated by the placement of transmitters for cellular telephones, Chang, Kloks, and Lee introduced the concept of maximum-clique transversal sets on graphs in 2001. In this paper, we study the weighted version of the maximum-clique transversal set problem for split grap...

  12. Stalkerid sisekujundusmaastikul / Jan Joonas Graps, Ken-Kristjan Ruut ; intervjueerinud Aale Kask

    Index Scriptorium Estoniae

    Graps, Jan Joonas, 1972-

    2008-01-01

    Sisearhitektide Jan Joonas Grapsi ja Ken-Kristjan Ruudu loomingust, tehtud tööde loetelu. Sarjast WooDoo. Pelgulinnas Kaera 22 asuva korteri (arhitekt Harry Klaar) ja Murastes asuva eramu (arhitekt Mart Kadarik) sisekujundusest

  13. Enzymatic desulfation of the red seaweeds agar by Marinomonas arylsulfatase.

    Science.gov (United States)

    Wang, Xueyan; Duan, Delin; Fu, Xiaoting

    2016-12-01

    Agar and sulfated galactans were isolated from the red seaweeds Gracilariopsis lemaneiformis and Gelidium amansii. A previously purified arylsulfatase from Marinomonas sp. FW-1 was used to remove sulfate groups in agar and sulfated galactans. After enzymatic desulfation, the sulfate content decreased to about 0.16% and gel strength increased about two folds. Moreover, there was no difference between the DNA electrophoresis spectrum on the gel of the arylsulfatase-treated agar and that of the commercial agarose. In order to reveal the desulfation ratio and site, chemical and structural identification of sulfated galactan were carried out. G. amansii sulfated galactan with 7.4% sulfated content was composed of galactose and 3,6-anhydro-l-galactose. Meanwhile, G. lemaneiformis sulfated galactan with 8.5% sulfated content was composed of galactose, 3,6-anhydro-l-galactose, 2-O-methyl-3,6-anhydro-l-galactose and xylose. Data from 13 C NMR, FT-IR, GC-MS provided evidence of sulfate groups at C-4 and C-6 of d-galactose and C-6 of l-galactose both in GRAP and GEAP. Data from GC-MS revealed that desulfation was carried out by the arylsulfatase at the sulfate bonds at C-4 and C-6 of d-galactose and C-6 of l-galactose, with a desulfation ratio of 83.4% and 86.0% against GEAP and GRAP, respectively. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. CCD research. [design, fabrication, and applications

    Science.gov (United States)

    Gassaway, J. D.

    1976-01-01

    The fundamental problems encountered in designing, fabricating, and applying CCD's are reviewed. Investigations are described and results and conclusions are given for the following: (1) the development of design analyses employing computer aided techniques and their application to the design of a grapped structure; (2) the role of CCD's in applications to electronic functions, in particular, signal processing; (3) extending the CCD to silicon films on sapphire (SOS); and (4) all aluminum transfer structure with low noise input-output circuits. Related work on CCD imaging devices is summarized.

  15. Graph of growth data - The Rice Growth Monitoring for The Phenotypic Functional Analysis | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us The Rice Growth Monitoring for The Phenotypic Functional Analysis Graph of growth data Data ...detail Data name Graph of growth data DOI 10.18908/lsdba.nbdc00945-003 Description of data contents The grap...h of chronological changes in root, coleoptile, the first leaf, and the second leaf. Data file File name: growth..._data_graph.zip File URL: ftp://ftp.biosciencedbc.jp/archive/agritogo-rice-phenome/LATEST/data/growth...e Update History of This Database Site Policy | Contact Us Graph of growth data -

  16. Calorimetry at industrial electron accelerators

    DEFF Research Database (Denmark)

    Miller, Arne; Kovacs, A.

    1985-01-01

    Calorimetry is a convenient way to measure doses at industrial electron accelerators, where high absorbed doses (1-100 kGy) are delivered at dose rates of 102-105 Gy s-1 or even higher. Water calorimeters have been used for this purpose for several years, but recently other materials such as grap......Calorimetry is a convenient way to measure doses at industrial electron accelerators, where high absorbed doses (1-100 kGy) are delivered at dose rates of 102-105 Gy s-1 or even higher. Water calorimeters have been used for this purpose for several years, but recently other materials...

  17. Quantitative relationship between SAR and temperature rise inside eyeball in a realistic human heat model for 1.5 GHz-microwave exposure; 1.5GHz maikuroha wo abita tobu real model ni okeru gankyunai no hikyushuritsu to josho ondo tono teiryo kankei

    Energy Technology Data Exchange (ETDEWEB)

    Takai, K.; Fujiwara, O. [Nagoya Institute of Technology, Nagoya (Japan)

    1997-12-20

    For investigating biological effects of a localized SAR (specific absorption rate) deposited in a human body for electromagnetic wave exposure, it is indispensable to graps a temperature-rise inside a human brain including the control center for the body temperature. This paper numerically analyzes a temperature-rise inside an eyeball of our developed realistic head model for 1.5 GHz microwave exposure, using the FD-TD (finite-difference time-domain) method. The computed results are validated in comparison with the data obtained by Taflove and his colleague. In order to examine a quantitative relationship between the localized SAR and temperature-rise, we also obtained a tissue amount over which the localized SAR should be averaged so as to well reflect the temperature-rise distribution inside the eyeball. 15 refs., 9 figs., 3 tabs.

  18. Jan ja Ken - vennad disainerid ja sisearhitektid / Jan Joonas Graps, Ken-Kristjan Ruut ; intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Graps, Jan Joonas, 1972-

    2009-01-01

    Jan Joonas Grapsi ja Ken-Kristjan Ruuduga nende loomingust ja kujundamispõhimõtetest. 2004. a. asutasid vennad oma sisearhitektuuri ja disainiga tegeleva firma Jan & Ken OÜ. Pälvisid Eesti Sisearhitektide Liidu 2008. aasta parima ühiskondliku interjööri preemia, EXPO 2010 Eesti paviljoni võistlusel 2. koha

  19. Development of a parallel trigger framework for rare decay searches

    CERN Document Server

    Pantaleo, Felice

    The simplicity of kaon decays (few decay channels, low final-state multiplicities) enable the possibility to reach an excellent sensitivity in the searches of lepton flavor violating decays. The experimental characteristics of decays like $K^+\\to \\pi^- \\mu^+ \\mu^+$ are very clear and allow an efficient background rejection. However, the measurement of this kind of events requires the production of a remarkable number of kaon decays. The bandwidth of tape recording system currently available does not allow the storage of all the produced events. A multi-stage selection of the potentially interesting events is required (trigger). At NA62, a first selection is done in real-time (response time $<1$ ms) by the level 0 trigger. The level 0 trigger is based on programmable logic (FPGA) that does not allow the same flexibility of the processors used for software programmable computers. The performance of parallel architectures like multi-cores CPUs and GPUs (Graphics Processing Units), located on computers grap...

  20. Manipulation of biological samples using micro and nano techniques.

    Science.gov (United States)

    Castillo, Jaime; Dimaki, Maria; Svendsen, Winnie Edith

    2009-01-01

    The constant interest in handling, integrating and understanding biological systems of interest for the biomedical field, the pharmaceutical industry and the biomaterial researchers demand the use of techniques that allow the manipulation of biological samples causing minimal or no damage to their natural structure. Thanks to the advances in micro- and nanofabrication during the last decades several manipulation techniques offer us the possibility to image, characterize and manipulate biological material in a controlled way. Using these techniques the integration of biomaterials with remarkable properties with physical transducers has been possible, giving rise to new and highly sensitive biosensing devices. This article reviews the different techniques available to manipulate and integrate biological materials in a controlled manner either by sliding them along a surface (2-D manipulation), by grapping them and moving them to a new position (3-D manipulation), or by manipulating and relocating them applying external forces. The advantages and drawbacks are mentioned together with examples that reflect the state of the art of manipulation techniques for biological samples (171 references).

  1. In vitro and in vivo effects of graphene oxide and reduced graphene oxide on glioblastoma

    DEFF Research Database (Denmark)

    Jaworski, Sławomir; Sawosz, Ewa; Kutwin, Marta

    2015-01-01

    Graphene and its related counterparts are considered the future of advanced nanomaterials owing to their exemplary properties. However, information about their toxicity and biocompatibility is limited. The objective of this study is to evaluate the toxicity of graphene oxide (GO) and reduced grap......, the level of apoptotic markers increased in rGO-treated tumors. We show that rGO induces cell death mostly through apoptosis, indicating the potential applicability of graphene in cancer therapy.......Graphene and its related counterparts are considered the future of advanced nanomaterials owing to their exemplary properties. However, information about their toxicity and biocompatibility is limited. The objective of this study is to evaluate the toxicity of graphene oxide (GO) and reduced...... graphene oxide (rGO) platelets, using U87 and U118 glioma cell lines for an in vitro model and U87 tumors cultured on chicken embryo chorioallantoic membrane for an in vivo model. The in vitro investigation consisted of structural analysis of GO and rGO platelets using transmission electron microscopy...

  2. SATCAP-B: a program for thermal-hydraulic design of 'Saturated Temperature Capsule'

    International Nuclear Information System (INIS)

    Harayama, Yasuo; Someya, Hiroyuki; Niimi, Motoji

    1989-11-01

    As an advanced irradiation technique, the JMTR (Japan Materials Testing Reactor) project is developing a 'Saturated Temperature Capsule' which water is injected in and boiled. When the water is kept at a constant pressure, the water temperature does not become higher than the saturated temperature. This type capsule is based on the conception of keeping the coolant to the saturated temperature and using the temperature control. In designing the capsule in which the inner coolant is injected, thermal performances have to be understood as exactly as possible. Then, a program (named SATCAP) was compiled to graps the thermal performance within the capsule. On the other hand, a 'Saturated Temperature Capsule' was made and irradiated in the JMTR core. It was indicated from supplied water temperatures recorded by thermo-couples attached in the capsule that heat transfer coefficients prefered models due to natural convection to models incorporated in the initial version of the program. Then, the program was revised by adding mainly heat transfer model based on natural convection. The present report describes the calculation procedure and guides of input and output for the revised program (SATCAP version-B). (author)

  3. Contribution of Environmental Surveillance Toward Interruption of Poliovirus Transmission in Nigeria, 2012-2015.

    Science.gov (United States)

    Johnson Muluh, Ticha; Hamisu, Abdullahi Walla; Craig, Kehinde; Mkanda, Pascal; Andrew, Etsano; Adeniji, Johnson; Akande, Adefunke; Musa, Audu; Ayodeji, Isiaka; Nicksy, Gumede; Banda, Richard; Tegegne, Sisay G; Nsubuga, Peter; Oyetunji, Ajiboye; Diop, Ousmane; Vaz, Rui G; Muhammad, Ado J G

    2016-05-01

    Cases of paralysis caused by poliovirus have decreased by >99% since the 1988 World Health Assembly's resolution to eradicate polio. The World Health Organization identified environmental surveillance (ES) of poliovirus in the poliomyelitis eradication strategic plan as an activity that can complement acute flaccid paralysis (AFP) surveillance. This article summarizes key public health interventions that followed the isolation of polioviruses from ES between 2012 and 2015. The grap method was used to collect 1.75 L of raw flowing sewage every 2-4 weeks. Once collected, samples were shipped at 4 °C to a polio laboratory for concentration. ES data were then used to guide program implementation. From 2012 to 2015, ES reported 97 circulating vaccine-derived polioviruses (cVDPV2) and 14 wild polioviruses. In 2014 alone, 54 cVDPV type 2 cases and 1 WPV type 1 case were reported. In Sokoto State, 58 cases of AFP were found from a search of 9426 households. A total of 2 252 059 inactivated polio vaccine and 2 460 124 oral polio vaccine doses were administered to children aged poliovirus transmission in Nigeria. © 2016 World Health Organization; licensee Oxford Journals.

  4. SEOM's Sentinel-3/OLCI' project CAWA: advanced GRASP aerosol retrieval

    Science.gov (United States)

    Dubovik, Oleg; litvinov, Pavel; Huang, Xin; Aspetsberger, Michael; Fuertes, David; Brockmann, Carsten; Fischer, Jürgen; Bojkov, Bojan

    2016-04-01

    The CAWA "Advanced Clouds, Aerosols and WAter vapour products for Sentinel-3/OLCI" ESA-SEOM project aims on the development of advanced atmospheric retrieval algorithms for the Sentinel-3/OLCI mission, and is prepared using Envisat/MERIS and Aqua/MODIS datasets. This presentation discusses mainly CAWA aerosol product developments and results. CAWA aerosol retrieval uses recently developed GRASP algorithm (Generalized Retrieval of Aerosol and Surface Properties) algorithm described by Dubovik et al. (2014). GRASP derives extended set of atmospheric parameters using multi-pixel concept - a simultaneous fitting of a large group of pixels under additional a priori constraints limiting the time variability of surface properties and spatial variability of aerosol properties. Over land GRASP simultaneously retrieves properties of both aerosol and underlying surface even over bright surfaces. GRAPS doesn't use traditional look-up-tables and performs retrieval as search in continuous space of solution. All radiative transfer calculations are performed as part of the retrieval. The results of comprehensive sensitivity tests, as well as results obtained from real Envisat/MERIS data will be presented. The tests analyze various aspects of aerosol and surface reflectance retrieval accuracy. In addition, the possibilities of retrieval improvement by means of implementing synergetic inversion of a combination of OLCI data with observations by SLSTR are explored. Both the results of numerical tests, as well as the results of processing several years of Envisat/MERIS data illustrate demonstrate reliable retrieval of AOD (Aerosol Optical Depth) and surface BRDF. Observed retrieval issues and advancements will be discussed. For example, for some situations we illustrate possibilities of retrieving aerosol absorption - property that hardly accessible from satellite observations with no multi-angular and polarimetric capabilities.

  5. Porphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional study.

    Science.gov (United States)

    Lombardo Bedran, Telma Blanca; Marcantonio, Rosemary Adriana C; Spin Neto, Rubens; Alves Mayer, Marcia Pinto; Grenier, Daniel; Spolidorio, Luis Carlos; Spolidorio, Denise Palomari

    2012-01-01

    Although previous studies have shown the presence of Porphyromonas endodontalis in chronic periodontitis associated with periapical lesions, the occurrence of this pathogen in diseased periodontal sites without periapical lesions has been poorly investigated. The aims of this study were to quantify P. endodontalis in patients with chronic periodontitis without periapical lesions, to evaluate the potential correlation of P. endodontalis with Porphyromonas gingivalis and Tannerella forsythia, and to evaluate the ability of periodontal treatment to reduce these pathogens. Patients with generalized chronic periodontitis were selected by recording clinical attachment level (CAL), probing depth (PD), and bleeding on probing (BOP). Subgingival samples from 30 diseased nonadjacent sites (CAL≥5 mm, PD between 5 and 7 mm and positive BOP) and 30 healthy nonadjacent sites (PD≤3 mm and negative BOP) were collected and subjected to microbial analysis by quantitative polymerase chain reaction (qPCR) The variables of age, PD, CAL and BOP of all individuals were analyzed using the paired t-test (GrapPad Prism5(®)). Data of bacteria quantification were subjected to a normality test (D'Agostino-Pearson Test). For bacterial correlation analysis, the Spearman correlation was used. Our results showed that diseased sites had significantly higher levels of P. endodontalis compared to healthy sites, similar to the results obtained for P. gingivalis and T. forsythia. The numbers of all bacterial species were reduced significantly after mechanical periodontal treatment. P. endodontalis was significantly correlated with the presence of T. forsythia and P. gingivalis in the diseased group. Our results suggest that there is a high prevalence of P. endodontalis, P. gingivalis and T. forsythia in periodontitis sites and that mechanical periodontal treatment is effective at reducing the pathogens studied.

  6. Porphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional study

    Science.gov (United States)

    Lombardo Bedran, Telma Blanca; Marcantonio, Rosemary Adriana C.; Spin Neto, Rubens; Alves Mayer, Marcia Pinto; Grenier, Daniel; Spolidorio, Luis Carlos; Spolidorio, Denise Palomari

    2012-01-01

    Background Although previous studies have shown the presence of Porphyromonas endodontalis in chronic periodontitis associated with periapical lesions, the occurrence of this pathogen in diseased periodontal sites without periapical lesions has been poorly investigated. Objective The aims of this study were to quantify P. endodontalis in patients with chronic periodontitis without periapical lesions, to evaluate the potential correlation of P. endodontalis with Porphyromonas gingivalis and Tannerella forsythia, and to evaluate the ability of periodontal treatment to reduce these pathogens. Design Patients with generalized chronic periodontitis were selected by recording clinical attachment level (CAL), probing depth (PD), and bleeding on probing (BOP). Subgingival samples from 30 diseased nonadjacent sites (CAL≥5 mm, PD between 5 and 7 mm and positive BOP) and 30 healthy nonadjacent sites (PD≤3 mm and negative BOP) were collected and subjected to microbial analysis by quantitative polymerase chain reaction (qPCR) The variables of age, PD, CAL and BOP of all individuals were analyzed using the paired t-test (GrapPad Prism5®). Data of bacteria quantification were subjected to a normality test (D'Agostino-Pearson Test). For bacterial correlation analysis, the Spearman correlation was used. Results Our results showed that diseased sites had significantly higher levels of P. endodontalis compared to healthy sites, similar to the results obtained for P. gingivalis and T. forsythia. The numbers of all bacterial species were reduced significantly after mechanical periodontal treatment. P. endodontalis was significantly correlated with the presence of T. forsythia and P. gingivalis in the diseased group. Conclusion Our results suggest that there is a high prevalence of P. endodontalis, P. gingivalis and T. forsythia in periodontitis sites and that mechanical periodontal treatment is effective at reducing the pathogens studied. PMID:22232719

  7. Porphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional study

    Directory of Open Access Journals (Sweden)

    Telma Blanca Lombardo Bedran

    2012-01-01

    Full Text Available Although previous studies have shown the presence of Porphyromonas endodontalis in chronic periodontitis associated with periapical lesions, the occurrence of this pathogen in diseased periodontal sites without periapical lesions has been poorly investigated.The aims of this study were to quantify P. endodontalis in patients with chronic periodontitis without periapical lesions, to evaluate the potential correlation of P. endodontalis with Porphyromonas gingivalis and Tannerella forsythia, and to evaluate the ability of periodontal treatment to reduce these pathogens.Patients with generalized chronic periodontitis were selected by recording clinical attachment level (CAL, probing depth (PD, and bleeding on probing (BOP. Subgingival samples from 30 diseased nonadjacent sites (CAL ≥ 5 mm, PD between 5 and 7 mm and positive BOP and 30 healthy nonadjacent sites (PD ≤ 3 mm and negative BOP were collected and subjected to microbial analysis by quantitative polymerase chain reaction (qPCR The variables of age, PD, CAL and BOP of all individuals were analyzed using the paired t-test (GrapPad Prism5®. Data of bacteria quantification were subjected to a normality test (D'Agostino-Pearson Test. For bacterial correlation analysis, the Spearman correlation was used.Our results showed that diseased sites had significantly higher levels of P. endodontalis compared to healthy sites, similar to the results obtained for P. gingivalis and T. forsythia. The numbers of all bacterial species were reduced significantly after mechanical periodontal treatment. P. endodontalis was significantly correlated with the presence of T. forsythia and P. gingivalis in the diseased group.Our results suggest that there is a high prevalence of P. endodontalis, P. gingivalis and T. forsythia in periodontitis sites and that mechanical periodontal treatment is effective at reducing the pathogens studied.

  8. Interactive SIGHT: textual access to simple bar charts

    Science.gov (United States)

    Demir, Seniz; Oliver, David; Schwartz, Edward; Elzer, Stephanie; Carberry, Sandra; Mccoy, Kathleen F.; Chester, Daniel

    2010-12-01

    Information graphics, such as bar charts and line graphs, are an important component of many articles from popular media. The majority of such graphics have an intention (a high-level message) to communicate to the graph viewer. Since the intended message of a graphic is often not repeated in the accompanying text, graphics together with the textual segments contribute to the overall purpose of an article and cannot be ignored. Unfortunately, these visual displays are provided in a format which is not readily accessible to everyone. For example, individuals with sight impairments who use screen readers to listen to documents have limited access to the graphics. This article presents a new accessibility tool, the Interactive SIGHT (Summarizing Information GrapHics Textually) system, that is intended to enable visually impaired users to access the knowledge that one would gain from viewing information graphics found on the web. The current system, which is implemented as a browser extension that works on simple bar charts, can be invoked by a user via a keystroke combination while navigating the web. Once launched, Interactive SIGHT first provides a brief summary that conveys the underlying intention of a bar chart along with the chart's most significant and salient features, and then produces history-aware follow-up responses to provide further information about the chart upon request from the user. We present two user studies that were conducted with sighted and visually impaired users to determine how effective the initial summary and follow-up responses are in conveying the informational content of bar charts, and to evaluate how easy it is to use the system interface. The evaluation results are promising and indicate that the system responses are well-structured and enable visually impaired users to answer key questions about bar charts in an easy-to-use manner. Post-experimental interviews revealed that visually impaired participants were very satisfied with

  9. Dynamic of decapod crustacean larvae on the entrance of Guanabara bay

    Directory of Open Access Journals (Sweden)

    Lohengrin Dias de Almeida Fernandes

    2002-12-01

    reprodutivo da espécie. Foi observado um padrão de dispersão similar para as larvas zoé dos portunídeos, grapsídeos e ocypodídeos; transporte para a região costeira adjacente pela superfície durante as marés de vazante noturnas.

  10. Rings Research in the Next Decade

    Science.gov (United States)

    Burns, J. A.; Tiscareno, M. S.

    2009-12-01

    -based observations. Members of the Rings White Paper Team include: Matthew S. Tiscareno (Cornell U), Nicole Albers (U of Colorado), Todd Bradley (U of Central Florida), André Brahic (U of Paris, France), Shawn Brooks (JPL), Joseph Burns (Cornell U), Carlos Chavez (UNAM, Mexico), Joshua Colwell (U of Central Florida), Jeff Cuzzi (NASA Ames), Imke de Pater (U of California), Luke Dones (SwRI), Richard Durisen (Indiana U), Michael Evans (Cornell U), Cecile Ferrari (CEA Saclay, France), Gianrico Filacchione (INAF-IASF, Italy), Silvia Giuliatti Winter (UNESP, Brazil), Mitch Gordon (SETI), Amara Graps (SwRI), Eberhard Gruen (MPI, Germany), Douglas Hamilton (U of Maryland), Matthew Hedman (Cornell U), Mihaly Horanyi (U of Colorado), Sascha Kempf (MPI, Germany), Harald Krueger (MPI, Germany), Steve Larson (U of Arizona), Mark Lewis (Trinity U), Jack Lissauer (NASA Ames), Colin Mitchell (CICLOPS/SSI), Carl Murray (QMUL, England), Philip Nicholson (Cornell U), Cathy Olkin (SwRI), Robert Pappalardo (JPL), Frank Postberg (MPI, Germany), Heikki Salo (U of Oulu, Finland), Juergen Schmidt (U of Potsdam, Germany), David Seal (JPL), Mark Showalter (SETI), Frank Spahn (U of Potsdam, Germany), Linda Spilker (JPL), Joseph Spitale (CICLOPS/SSI), Ralf Srama (MPI, Germany), Miodrag Sremcevic (U of Colorado), Glen Stewart (U of Colorado), John Weiss (Carleton College), Padma Yanamandra-Fisher (JPL)