75 FR 30782 - Reorganization/Expansion of Foreign-Trade Zone 20; Hampton Roads, VA, Area

Science.gov (United States)

2010-06-02

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1683] Reorganization/Expansion of Foreign-Trade Zone 20; Hampton Roads, VA, Area Pursuant to its authority under the Foreign-Trade Zones Act...) in the Hampton Roads, Virginia, area within the Norfolk Customs and Border Protection port of entry...

40 CFR 22.37 - Supplemental rules governing administrative proceedings under the Solid Waste Disposal Act.

Science.gov (United States)

2010-07-01

... administrative proceedings under the Solid Waste Disposal Act. 22.37 Section 22.37 Protection of Environment... Supplemental rules governing administrative proceedings under the Solid Waste Disposal Act. (a) Scope. This... sections 3005(d) and (e), 3008, 9003 and 9006 of the Solid Waste Disposal Act (42 U.S.C. 6925(d) and (e...

The role of the Government Energy Efficiency Act in the National Energy Act of 1992

International Nuclear Information System (INIS)

Good, L.; Williams, D.R.

1993-01-01

Last year Senator John Glenn's Government Energy Efficiency Act to reform energy management in the Federal Government was adopted entirely into the Senate's comprehensive energy bill. This year key portions of an equivalent bill were incorporated into the House of Representatives comprehensive energy bill after intensive lobbying by AEE's National Capital Chapter. According to a House staffer who played a key role in the bill, the section on energy manager training was included as a direct result of the Chapter's persuasion. Each bill passed in its respective house. At the time of this writing, in the spring of 1992, the two houses are scheduled to go into conference and attempt to merge their separate bills into one National Energy Act of 1992. The 102nd Congress seems determined to establish a national energy policy before election time, but the two houses take very different approaches to the problem, The bill could be voted into law during or just before the 15th World Energy Engineering Congress (WEEC). This paper will discuss some of the strengths and loopholes that apply to the Federal sector. The presentation of this paper at WEEC in October will bring AEE members up to the minute on these developments

Drilling reorganizes

Science.gov (United States)

Richman, Barbara T.

As the first in a proposed series of steps that would move scientific ocean drilling from its own niche within the National Science Foundation's (NSF) Directorate for Astronomical, Atmospheric, Earth, and Ocean Sciences (AAEO) into the agency's Division of Ocean Sciences, Grant Gross, division director, has been appointed acting director of the Office of Scientific Ocean Drilling (OSOD). Gross will retain the directorship of the division, which also is part of AAEO. Allen M. Shinn, Jr., OSOD director for nearly 2 years, has been reassigned effective July 10 to a position in NSF's Office of Planning and Resource Management.The move aims to tie drilling operations more closely to the science with which it is associated, Gross said. This first step is an organizational response to the current leaning toward using a commercial drilling vessel as the drilling platform, he said. Before the market for such commercial drill ships opened (Eos, February 22, 1983, p . 73), other ship options for scientific ocean drilling included refurbishing the aging Glomar Challenger or renovating, at great expense, the Glomar Explorer. A possible next step in the reorganization is to make OSOD the third section within the Ocean Sciences Division. Currently, the division is divided into the Oceanographic Facilities and Support Section and the Ocean Sciences Research Section.

Massive cortical reorganization in sighted Braille readers.

Science.gov (United States)

Siuda-Krzywicka, Katarzyna; Bola, Łukasz; Paplińska, Małgorzata; Sumera, Ewa; Jednoróg, Katarzyna; Marchewka, Artur; Śliwińska, Magdalena W; Amedi, Amir; Szwed, Marcin

2016-03-15

The brain is capable of large-scale reorganization in blindness or after massive injury. Such reorganization crosses the division into separate sensory cortices (visual, somatosensory...). As its result, the visual cortex of the blind becomes active during tactile Braille reading. Although the possibility of such reorganization in the normal, adult brain has been raised, definitive evidence has been lacking. Here, we demonstrate such extensive reorganization in normal, sighted adults who learned Braille while their brain activity was investigated with fMRI and transcranial magnetic stimulation (TMS). Subjects showed enhanced activity for tactile reading in the visual cortex, including the visual word form area (VWFA) that was modulated by their Braille reading speed and strengthened resting-state connectivity between visual and somatosensory cortices. Moreover, TMS disruption of VWFA activity decreased their tactile reading accuracy. Our results indicate that large-scale reorganization is a viable mechanism recruited when learning complex skills.

[The activity of the State Sanitary Inspectorate after implementation of the act of January, 23 2009 "Amending certain acts regarding reorganization and redistribution of competences of the public administration at the provincial level"].

Science.gov (United States)

Rudaś, Dariusz; Skórczewski, Krzysztof

2011-01-01

The restructuring of the State Sanitary Inspectorate was determined by the need to adjust the existing system to the new structure- and task-oriented standards introduced by the administrative reforms at the provincial level. This brought about a lot of changes in the way State County Sanitary Inspectors operate. For first few months after the enforcement of the Act of January 23.2009 amending certain acts regarding reorganization and redistribution of competences of the public administration at the provincial level (Journal of Laws, No. 92, item. 753, 2009) brought about a lot of ambiguities and expectations. Such unresolved issues are typical for the initial or transition period after implementation of a new law. The approach to the operation of the State Sanitary Inspectorate at the county level depicted in the article lays the emphasis on the challenges in the legal and task-oriented domain that arose after coming into force of the aforementioned amendment. By way of conclusion, the authors of the article briefly summaries the practical outcomes of the transformations undergone by the State Sanitary Inspectorate at the county level.

Co-Plaintigff in Judicial Reorganization

Directory of Open Access Journals (Sweden)

Liliane Gonçalves Matos

2016-12-01

Full Text Available The aim of the study it was to analyze the possibility of the economic group file a single request for judicial reorganization. Concerning the methodology, the study is a descriptive - analytic research, analyzing the legal doctrines and jurisprudence about the subject. It has been shown that the reorganization of groups, instead of separated companies may result benefits, as a company of the group can help to recover the others that are facing difficulties, but there is the possibility to create a negative incentive for the development of global business activity. It was concluded that the active joinder in bankruptcy is feasible, but it would be more prudent for each group company present its own reorganization  plan.

Hierarchical reorganization of dimensions in OLAP visualizations.

Science.gov (United States)

Lafon, Sébastien; Bouali, Fatma; Guinot, Christiane; Venturini, Gilles

2013-11-01

In this paper, we propose a new method for the visual reorganization of online analytical processing (OLAP) cubes that aims at improving their visualization. Our method addresses dimensions with hierarchically organized members. It uses a genetic algorithm that reorganizes k-ary trees. Genetic operators perform permutations of subtrees to optimize a visual homogeneity function. We propose several ways to reorganize an OLAP cube depending on which set of members is selected for the reorganization: all of the members, only the displayed members, or the members at a given level (level by level approach). The results that are evaluated by using optimization criteria show that our algorithm has a reliable performance even when it is limited to 1 minute runs. Our algorithm was integrated in an interactive 3D interface for OLAP. A user study was conducted to evaluate our approach with users. The results highlight the usefulness of reorganization in two OLAP tasks.

42 CFR 137.305 - May Self-Governance Tribes act as lead, cooperating, or joint lead agencies for environmental...

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false May Self-Governance Tribes act as lead, cooperating... HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Nepa Process § 137.305 May Self-Governance...-Governance Tribes assuming Federal environmental responsibilities for construction projects under section 509...

Proposal on state affairs and government system for next government

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-11-15

The contents of this book are introduction of need of study and purpose, building ecosystem to create jobs, consolidation of social innovation to improve life quality, construction of infrastructure to revitalize region, construction of new digital ecosystem, building of effective intellectual property system, creation of future competitiveness with scientific technology, establishment of raising of creative person and comprehensive discussion on reorganization of government system like need, principle, feature, difficulty, and arrangement of discussion.

Proposal on state affairs and government system for next government

International Nuclear Information System (INIS)

2012-11-01

The contents of this book are introduction of need of study and purpose, building ecosystem to create jobs, consolidation of social innovation to improve life quality, construction of infrastructure to revitalize region, construction of new digital ecosystem, building of effective intellectual property system, creation of future competitiveness with scientific technology, establishment of raising of creative person and comprehensive discussion on reorganization of government system like need, principle, feature, difficulty, and arrangement of discussion.

Large impact of reorganization energy on photovoltaic conversion due to interfacial charge-transfer transitions.

Science.gov (United States)

Fujisawa, Jun-ichi

2015-05-14

Interfacial charge-transfer (ICT) transitions are expected to be a novel charge-separation mechanism for efficient photovoltaic conversion featuring one-step charge separation without energy loss. Photovoltaic conversion due to ICT transitions has been investigated using several TiO2-organic hybrid materials that show organic-to-inorganic ICT transitions in the visible region. In applications of ICT transitions to photovoltaic conversion, there is a significant problem that rapid carrier recombination is caused by organic-inorganic electronic coupling that is necessary for the ICT transitions. In order to solve this problem, in this work, I have theoretically studied light-to-current conversions due to the ICT transitions on the basis of the Marcus theory with density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations. An apparent correlation between the reported incident photon-to-current conversion efficiencies (IPCE) and calculated reorganization energies was clearly found, in which the IPCE increases with decreasing the reorganization energy consistent with the Marcus theory in the inverted region. This activation-energy dependence was systematically explained by the equation formulated by the Marcus theory based on a simple excited-state kinetic scheme. This result indicates that the reduction of the reorganization energy can suppress the carrier recombination and enhance the IPCE. The reorganization energy is predominantly governed by the structural change in the chemical-adsorption moiety between the ground and ICT excited states. This work provides crucial knowledge for efficient photovoltaic conversion due to ICT transitions.

40 CFR 2.305 - Special rules governing certain information obtained under the Solid Waste Disposal Act, as amended.

Science.gov (United States)

2010-07-01

... information obtained under the Solid Waste Disposal Act, as amended. 2.305 Section 2.305 Protection of... § 2.305 Special rules governing certain information obtained under the Solid Waste Disposal Act, as amended. (a) Definitions. For purposes of this section: (1) Act means the Solid Waste Disposal Act, as...

Could LC-NE-Dependent Adjustment of Neural Gain Drive Functional Brain Network Reorganization?

Directory of Open Access Journals (Sweden)

Carole Guedj

2017-01-01

Full Text Available The locus coeruleus-norepinephrine (LC-NE system is thought to act at synaptic, cellular, microcircuit, and network levels to facilitate cognitive functions through at least two different processes, not mutually exclusive. Accordingly, as a reset signal, the LC-NE system could trigger brain network reorganizations in response to salient information in the environment and/or adjust the neural gain within its target regions to optimize behavioral responses. Here, we provide evidence of the co-occurrence of these two mechanisms at the whole-brain level, in resting-state conditions following a pharmacological stimulation of the LC-NE system. We propose that these two mechanisms are interdependent such that the LC-NE-dependent adjustment of the neural gain inferred from the clustering coefficient could drive functional brain network reorganizations through coherence in the gamma rhythm. Via the temporal dynamic of gamma-range band-limited power, the release of NE could adjust the neural gain, promoting interactions only within the neuronal populations whose amplitude envelopes are correlated, thus making it possible to reorganize neuronal ensembles, functional networks, and ultimately, behavioral responses. Thus, our proposal offers a unified framework integrating the putative influence of the LC-NE system on both local- and long-range adjustments of brain dynamics underlying behavioral flexibility.

Firm Reorganization : Social Control or Social Contract?

NARCIS (Netherlands)

Aalbers, Hendrik Leendert; Dolfsma, Wilfred; Blinde-Leerentveld, Rowan

Firm reorganizations deeply affect employees. Management can reorganize in different ways, focusing on costs or acknowledging the involvement of employees. The latter implies following a social contract that complements incomplete (formal) labor contracts. Little is known about how the way in which

Nuclear Protections and Safety Act of 1987. Report of the Committee on Governmental Affairs, United States Senate together with Additional Views to Accompany S. 1085, One Hundredth Congress, First Session

International Nuclear Information System (INIS)

Anon.

1987-01-01

The Senate report on S. 1085 suggests several amendments to the recommended bill which would make oversight of nuclear facility safety an independent board. The legislation responds to concerns that there is no justification for DOE facilities to be exempt from this kind of oversight, and that health and safety standards are as important at nuclear weapons and materials facilities as elsewhere. The report traces the emergence of the nuclear age and the different treatment of government and commercial facilities. There is evidence of a lack of concern for employee health and safety at some government installations. The report summarizes the four titles of the bill, reviews the four days of public hearings, and analyzes the bill by section. It notes changes that will result in the Energy Reorganization Act of 1974, the Atomic Energy Act of 1954, and the Department of Energy Organization Act

76 FR 65496 - Reorganization of Foreign-Trade Zone 119 Under Alternative Site Framework, Minneapolis/St. Paul, MN

Science.gov (United States)

2011-10-21

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1790] Reorganization of Foreign-Trade Zone 119 Under Alternative Site Framework, Minneapolis/St. Paul, MN Pursuant to its authority under the Foreign-Trade Zones Act of June 18, 1934, as amended (19 U.S.C. 81a-81u), the Foreign-Trade Zones Board...

76 FR 59999 - Submission for OMB Review; Comment Request

Science.gov (United States)

2011-09-28

... Application, 113 hours; Reorganization/ Expansion of General-Purpose Zone, 99 hours; and Request for..., manufacturing authority, or for expansion/reorganization of an existing zone. The FTZ Act and Regulations..., local, or tribal government; not-for-profit institutions; business or other for-profit organizations...

Prolonged reorganization of thiol-capped Au nanoparticles layered structures

Directory of Open Access Journals (Sweden)

Sarathi Kundu

2013-09-01

Full Text Available Prolonged reorganization behaviour of mono-, di-, tri- and multi-layer films of Au nanoparticles prepared by Langmuir-Blodgett method on hydrophobic Si(001 substrates have been studied by using X-ray scattering techniques. Out-of-plane study shows that although at the initial stage the reorganization occurs through the compaction of the films keeping the layered structure unchanged but finally all layered structures modify to monolayer structure. Due to this reorganization the Au density increases within the nanometer thick films. In-plane study shows that inside the reorganized films Au nanoparticles are distributed randomly and the particle size modifies as the metallic core of Au nanoparticles coalesces.

75 FR 40754 - Government in the Sunshine Act Regulations of the National Science Board

Science.gov (United States)

2010-07-14

... NATIONAL SCIENCE FOUNDATION 45 CFR Part 614 RIN 3145-AA53 Government in the Sunshine Act Regulations of the National Science Board AGENCY: National Science Board (NSB), National Science Foundation (NSF). ACTION: Direct final rule. SUMMARY: The National Science Board (NSB) National Science Foundation...

Effect of the methionine ligand on the reorganization energy of the type-1 copper site of nitrite Reductase

DEFF Research Database (Denmark)

Farver, Ole; Wijma, Hein J.; MacPherson, Iain

2007-01-01

Copper-containing nitrite reductase harbors a type-1 and a type-2 Cu site. The former acts as the electron acceptor site of the enzyme, and the latter is the site of catalytic action. The effect of the methionine ligand on the reorganization energy of the type-1 site was explored by studying...

Rotational reorganization of doped cholesteric liquid crystalline films

NARCIS (Netherlands)

Eelkema, R.; M. Pollard, M.; Katsonis, N.; Vicario, J.; J. Broer, D.; Feringa, B.L.

2006-01-01

In this paper an unprecedented rotational reorganization of cholesteric liquid crystalline films is described. This rotational reorganization results from the conversion of a chiral molecular motor dopant to an isomer with a different helical twisting power, leading to a change in the cholesteric

Government Performance and Results Act Reporting on Defense Working Capital Funds Net Operating Results

National Research Council Canada - National Science Library

2001-01-01

.... The overall objective of the audit was to determine whether the net operating results for the activity groups of the Defense Working Capital Fund were consistently and accurately compiled. We also assessed internal controls to determine whether management complied with the Government Performance and Results Act of 1993.

Emergent reorganization of an evolving experimental landscape under changing climatic forcing

Science.gov (United States)

Singh, A.; Tejedor, A.; Zaliapin, I. V.; Reinhardt, L.; Foufoula-Georgiou, E.

2014-12-01

Understanding landscape re-organization under changing climatic forcing is fundamental to advancing our understanding of geomorphic transport laws under transient conditions, developing predictive models of landscape response to external perturbations, and interpreting the stratigraphic record for past climates by incorporating possible regime shifts. Real landscape observations for long-term analysis are limited and to this end a high resolution controlled laboratory experiment was conducted at the St. Anthony Falls laboratory at the University of Minnesota. Elevation data were collected at temporal resolution of 5 mins and spatial resolution of 0.5 mm as the landscape approached steady state (for a constant uplift and precipitation rate) and in the transient state (under the same uplift and 5x precipitation). The results reveal rapid topographic re-organization under a five-fold precipitation increase with the fluvial regime expanding into previously debris dominated regime, accelerated erosion happening at hillslope scales, and rivers shifting from an erosion-limited to a transport-limited regime. By studying the space-time structure of the individual erosional and depositional events in terms of their size, location, clustering, and total volume we report complex space-time patterns of change which are scale-dependent and bounded by the river network topology. At the same time, the river network topology itself adjusts at smaller scales, with new channels added to accommodate increased hillslope erosional transport, further adjusting the landscape. Some new ideas related to landscape variability and entropy evolution at different scales during steady and transient states and the possibility of analyzing the self-organization with Optimal Mass Transport (OMT) metrics to infer possible underlying "optimality" principles governing the re-organization will also be presented.

Long term fault system reorganization of convergent and strike-slip systems

Science.gov (United States)

Cooke, M. L.; McBeck, J.; Hatem, A. E.; Toeneboehn, K.; Beyer, J. L.

2017-12-01

Laboratory and numerical experiments representing deformation over many earthquake cycles demonstrate that fault evolution includes episodes of fault reorganization that optimize work on the fault system. Consequently, the mechanical and kinematic efficiencies of fault systems do not increase monotonically through their evolution. New fault configurations can optimize the external work required to accommodate deformation, suggesting that changes in system efficiency can drive fault reorganization. Laboratory evidence and numerical results show that fault reorganization within accretion, strike-slip and oblique convergent systems is associated with increasing efficiency due to increased fault slip (frictional work and seismic energy) and commensurate decreased off-fault deformation (internal work and work against gravity). Between episodes of fault reorganization, fault systems may become less efficient as they produce increasing off fault deformation. For example, laboratory and numerical experiments show that the interference and interaction between different fault segments may increase local internal work or that increasing convergence can increase work against gravity produced by a fault system. This accumulation of work triggers fault reorganization as stored work provides the energy required to grow new faults that reorganize the system to a more efficient configuration. The results of laboratory and numerical experiments reveal that we should expect crustal fault systems to reorganize following periods of increasing inefficiency, even in the absence of changes to the tectonic regime. In other words, fault reorganization doesn't require a change in tectonic loading. The time frame of fault reorganization depends on fault system configuration, strain rate and processes that relax stresses within the crust. For example, stress relaxation may keep pace with stress accumulation, which would limit the increase in the internal work and gravitational work so that

Exploring Low Internal Reorganization Energies for Silicene Nanoclusters

KAUST Repository

Pablo-Pedro, Ricardo

2017-08-17

High-performance materials rely on small reorganization energies to facilitate both charge separation and charge transport. Here, we performed DFT calculations to predict small reorganization energies of rectangular silicene nanoclusters with hydrogen-passivated edges denoted by H-SiNC. We observe that across all geometries, H-SiNCs feature large electron affinities and highly stabilized anionic states, indicating their potential as n-type materials. Our findings suggest that fine-tuning the size of H-SiNCs along the zigzag and armchair directions may permit the design of novel n-type electronic materials and spinctronics devices that incorporate both high electron affinities and very low internal reorganization energies.

Has the Federal Government the power to instruct State authorities in procedures under the Atomic Energy Act

International Nuclear Information System (INIS)

Ost, W.; Pelzer, N.

1979-01-01

The differences in opinion which have emerged between the Federal Government and ministers of the State of North Rhine-Westphalia about further permits to be issued for construction of the SNR 300 fast breeder reactor at Kalkar have raised the question of whether the Federal Government has the right to issue directives to a state authority to grant a permit. Close examination of the legal aspects indicates that hardly any literature and no court decisions are as yet available on this problem, because it has never played a role so far. However, it is undisputed that there is such a right to give instructions. Under the Constitution and the Atomic Energy Act the state authorities are responsible for granting permits, but only as agents acting on behalf of the federal authority. Such instructions must be in accordance with the Atomic Energy Act and the objective sought must be lawful for the instructions to be effective. (orig.) [de

40 CFR 2.308 - Special rules governing certain information obtained under the Federal Food, Drug and Cosmetic Act.

Science.gov (United States)

2010-07-01

... information obtained under the Federal Food, Drug and Cosmetic Act. 2.308 Section 2.308 Protection of... § 2.308 Special rules governing certain information obtained under the Federal Food, Drug and Cosmetic... Cosmetic Act, as amended, 21 U.S.C. 301 et seq. (2) Petition means a petition for the issuance of a...

Reorganization of Practicum in Initial Teacher Education: A Search for Challenges in Implementation by Ex-Ante Evaluation

Directory of Open Access Journals (Sweden)

Laila Niklasson

2015-10-01

Full Text Available The background of the study is a perceived need of increasing quality in practice during Initial Teacher Education (ITE in Sweden. In order to achieve higher quality, the government encourages reorganization towards a limited number of practice schools, competence development for supervisors and research focusing on the selected practice schools.  The aim of this study is to present and critically discuss prerequisites for implementation of the reform. The paper focuses on how a preliminary logic model and a SWOT analysis can show challenges encountered during the implementation of the reorganization. By using the logic model and the SWOT analysis an ex-ante evaluation was carried out in two steps. The results disclosed that the motivation behind reorganization, improving the quality of practicum, might meet some challenges. Indicators of higher quality being attained are not provided; the local organization is expected to construct such indicators during the process. In contrast to the challenges the results showed that the implementation was supported by earlier good relations and a common idea of developing practicum in ITE. The implication for implementation is a need to have a dialogue about indicators for quality among different stakeholders in ITE. Without such a dialogue it can be disputed whether the change in practicum was successful.

Exploring Low Internal Reorganization Energies for Silicene Nanoclusters

Science.gov (United States)

Pablo-Pedro, Ricardo; Lopez-Rios, Hector; Mendoza-Cortes, Jose-L.; Kong, Jing; Fomine, Serguei; Van Voorhis, Troy; Dresselhaus, Mildred S.

2018-05-01

This paper is a contribution to the Physical Review Applied collection in memory of Mildred S. Dresselhaus. High-performance materials rely on small reorganization energies to facilitate both charge separation and charge transport. Here, we perform density-functional-theory calculations to predict small reorganization energies of rectangular silicene nanoclusters with hydrogen-passivated edges denoted by H-SiNC. We observe that across all geometries, H-SiNCs feature large electron affinities and highly stabilized anionic states, indicating their potential as n -type materials. Our findings suggest that fine-tuning the size of H-SiNCs along the "zigzag" and "armchair" directions may permit the design of novel n -type electronic materials and spintronics devices that incorporate both high electron affinities and very low internal reorganization energies.

Acquisition Services Reorganization at the General Services Administration

National Research Council Canada - National Science Library

Smith, Stephanie

2005-01-01

Congress enacted the Federal Property and Administrative Services Act in 1949 to provide for an "economical and efficient system" for the Federal Government's management of real property, procurement...

Expediting Scientific Data Analysis with Reorganization of Data

Energy Technology Data Exchange (ETDEWEB)

Byna, Surendra; Wu, Kesheng

2013-08-19

Data producers typically optimize the layout of data files to minimize the write time. In most cases, data analysis tasks read these files in access patterns different from the write patterns causing poor read performance. In this paper, we introduce Scientific Data Services (SDS), a framework for bridging the performance gap between writing and reading scientific data. SDS reorganizes data to match the read patterns of analysis tasks and enables transparent data reads from the reorganized data. We implemented a HDF5 Virtual Object Layer (VOL) plugin to redirect the HDF5 dataset read calls to the reorganized data. To demonstrate the effectiveness of SDS, we applied two parallel data organization techniques: a sort-based organization on a plasma physics data and a transpose-based organization on mass spectrometry imaging data. We also extended the HDF5 data access API to allow selection of data based on their values through a query interface, called SDS Query. We evaluated the execution time in accessing various subsets of data through existing HDF5 Read API and SDS Query. We showed that reading the reorganized data using SDS is up to 55X faster than reading the original data.

45 CFR 73.735-902 - Reporting requirements for certain employees not covered by the Ethics in Government Act of 1978.

Science.gov (United States)

2010-10-01

... covered by the Ethics in Government Act of 1978. 73.735-902 Section 73.735-902 Public Welfare DEPARTMENT... Interests § 73.735-902 Reporting requirements for certain employees not covered by the Ethics in Government... decision-making responsibility for the following matters: (i) Contracting or procurement, (ii...

Towards a Micro Foundation of Leadership, Governance, and Management in Universities

DEFF Research Database (Denmark)

Blaschke, Steffen; Frost, Jetta; Hattke, Fabian

2014-01-01

Leadership, governance, and management are frequently conceptualized as conflictory institutional logics. The recent shift to a 'new managerialism' in universities, for example, clearly favors business-like leadership and management styles over collegial governance practices. This article provides...... a micro foundation of leadership, governance, and management in universities based on the underlying communication of strategic issues among governing bodies. Reporting on a longitudinal case study of a comprehensive reorganization of a German university, it illustrates how institutional logics translate...... into micro patterns of communication. The findings suggest that leadership, governance, and management are not necessarily conflictory but reflect in four complementary micro patterns. Rather than 'managerialism' replacing 'collegialism,' organizational change unfolds in oscillating sequences of these four...

Theoretical study of substitution effects on molecular reorganization energy in organic semiconductors.

Science.gov (United States)

Geng, Hua; Niu, Yingli; Peng, Qian; Shuai, Zhigang; Coropceanu, Veaceslav; Brédas, Jean-Luc

2011-09-14

Chemical substitutions are powerful molecular design tools to enhance the performance of organic semiconductors, for instance, to improve solubility, intermolecular stacking, or film quality. However, at the microscopic level, substitutions in general tend to increase the molecular reorganization energy and thus decrease the intrinsic charge-carrier mobility. Through density functional theory calculations, we elucidate strategies that could be followed to reduce the reorganization energy upon chemical substitution. Specific examples are given here for hole-transport materials including indolo-carbazoles and several triarylamine derivatives. Through decomposition of the total reorganization energy into the internal coordinate space, we are able to identify the molecular segment that provides the most important contributions to the reorganization energy. It is found that when substitution reduces (enhances) the amplitude of the relevant frontier molecular orbital in that segment, the total reorganization energy decreases (increases). In particular, chlorination at appropriate positions can significantly reduce the reorganization energy. Several other substituents are shown to play a similar role, to a greater or lesser extent. © 2011 American Institute of Physics

Should a reorganization of France's nuclear industry be envisaged?

International Nuclear Information System (INIS)

Finon, D.

2011-01-01

Recent proposals to reorganize the French reactor industry to increase its export capability are reviewed here. Based on its criticism of the technology on offer to export markets, the Rousselly report recommended making the national electricity company a lead company free to negotiate the sale of reactors of its choosing (including Gen2 reactors) and to make the French manufacturer the sub-contractor of the former. The Government did not adopt these recommendations and rightly so. Based on an analysis of the changing world market for reactors, perspective can be gained on the criticism made of Areva about its marketing thrust, as well as the advantage to be gained by broadening its reactor catalogue. This analysis brings out and underlines the significance of the technological and industrial resources of Areva relative to competitors and the relatively meagre advantage of architect/assembler and operator provided by the national electricity company in the conquest of export markets. In the final analysis, the mercantile approach proposed by the champions of this reform to improve competitiveness with low cost nuclear newcomers was ruled out the Government, even before the Fukushima accident. What is really required is a little more export coordination between the two entities. (author)

26 CFR 31.6302(c)-3 - Use of Government depositaries in connection with tax under the Federal Unemployment Tax Act.

Science.gov (United States)

2010-04-01

... with tax under the Federal Unemployment Tax Act. 31.6302(c)-3 Section 31.6302(c)-3 Internal Revenue...) § 31.6302(c)-3 Use of Government depositaries in connection with tax under the Federal Unemployment Tax... transfer. For the requirement to deposit tax under the Federal Unemployment Tax Act by electronic funds...

Reorganizing Nigeria's Vaccine Supply Chain Reduces Need For Additional Storage Facilities, But More Storage Is Required.

Science.gov (United States)

Shittu, Ekundayo; Harnly, Melissa; Whitaker, Shanta; Miller, Roger

2016-02-01

One of the major problems facing Nigeria's vaccine supply chain is the lack of adequate vaccine storage facilities. Despite the introduction of solar-powered refrigerators and the use of new tools to monitor supply levels, this problem persists. Using data on vaccine supply for 2011-14 from Nigeria's National Primary Health Care Development Agency, we created a simulation model to explore the effects of variance in supply and demand on storage capacity requirements. We focused on the segment of the supply chain that moves vaccines inside Nigeria. Our findings suggest that 55 percent more vaccine storage capacity is needed than is currently available. We found that reorganizing the supply chain as proposed by the National Primary Health Care Development Agency could reduce that need to 30 percent more storage. Storage requirements varied by region of the country and vaccine type. The Nigerian government may want to consider the differences in storage requirements by region and vaccine type in its proposed reorganization efforts. Project HOPE—The People-to-People Health Foundation, Inc.

76 FR 71919 - Corporate Reorganizations; Allocation of Basis in “All Cash D” Reorganizations

Science.gov (United States)

2011-11-21

... issuing temporary regulations that provide guidance regarding the determination of the basis of stock or securities in a reorganization where no stock or securities of the issuing corporation is issued and... the share of stock of the issuing corporation to which the basis, if any, of the stock or securities...

Grading Gradients: Evaluating Evidence for Time-dependent Memory Reorganization in Experimental Animals

Directory of Open Access Journals (Sweden)

Katherine G. Akers

2009-01-01

Full Text Available In humans, hippocampal damage typically produces temporally graded retrograde amnesia, with relative sparing of remote memories compared to recent memories. This observation led to the idea that as memories age, they are reorganized in a time-dependent manner. Here, we evaluate evidence for time-dependent memory reorganization in animal models. We conclude that, although hippocampal lesions may not always produce temporal gradients under all conditions, studies using alternate experimental approaches consistently support the idea that memories reorganize over time—becoming less dependent on the hippocampus and more dependent on a cortical network. We further speculate on the processes that drive memory reorganization such as sleep, memory reactivation, synaptic plasticity, and neurogenesis.

Privacy Act

Science.gov (United States)

Learn about the Privacy Act of 1974, the Electronic Government Act of 2002, the Federal Information Security Management Act, and other information about the Environmental Protection Agency maintains its records.

Designed azurins show lower reorganization free energies for intraprotein electron transfer

DEFF Research Database (Denmark)

Farver, Ole; Marshall, Nicholas M; Wherland, Scot

2013-01-01

Low reorganization free energies are necessary for fast electron transfer (ET) reactions. Hence, rational design of redox proteins with lower reorganization free energies has been a long-standing challenge, promising to yield a deeper understanding of the underlying principles of ET reactivity...

26 CFR 54.4980B-9 - Business reorganizations and employer withdrawals from multiemployer plans.

Science.gov (United States)

2010-04-01

...-9 Business reorganizations and employer withdrawals from multiemployer plans. The following... multiemployer plans: Q-1: For purposes of this section, what are a business reorganization, a stock sale, and an... 26 Internal Revenue 17 2010-04-01 2010-04-01 false Business reorganizations and employer...

INTERACTION BETWEEN MODELS OF THE LIFE CYCLE OF INDUSTRIAL ENTERPRISE AND CYCLE OF ITS REORGANIZATION

Directory of Open Access Journals (Sweden)

Chulkov Vitaliy Olegovich

2012-10-01

Full Text Available The objective of this scientific research is to develop a theoretical model of organizational and technology-related processes of reorganization of industrial enterprises, as well as their interaction. Multipoint logic notions of growth and interaction phases are used as research methods. The author describes the basic stages of reorganization, the life cycle of industrial enterprises and the cycle of their transformation. The processes are presented as an infographical image that represents a concentric model of interaction. This concentric model represents interaction between two or more phases. The process is entitled infografical modeling on the polyfunctional level. The concentric model moves both clockwise and anti-clockwise. Basic organizational and technological processes of reorganization of industrial enterprises that include decision making in terms of expediency of reorganization, design, construction, and performance of industrial enterprises at full capacity, and further operation of the industrial enterprise are described in the paper. Attainment of this objective, namely, reorganization of an industrial enterprise, involves a huge amount of resources, including labour resources that need interaction with all parties of reorganization; therefore, the concentric model of interaction describing the basic cycle of reorganization, the life cycle of an industrial enterprise and the cycle of its conversion is a trustworthy representation of this process. The proposed concentric model of interaction should be used in the design of organizational and technology-related processes for integrated consideration of reorganization of enterprises required to understand and improve the efficiency of reorganizations and to control the reorganization of industrial facilities.

Lesion characteristics driving right-hemispheric language reorganization in congenital left-hemispheric brain damage.

Science.gov (United States)

Lidzba, Karen; de Haan, Bianca; Wilke, Marko; Krägeloh-Mann, Ingeborg; Staudt, Martin

2017-10-01

Pre- or perinatally acquired ("congenital") left-hemispheric brain lesions can be compensated for by reorganizing language into homotopic brain regions in the right hemisphere. Language comprehension may be hemispherically dissociated from language production. We investigated the lesion characteristics driving inter-hemispheric reorganization of language comprehension and language production in 19 patients (7-32years; eight females) with congenital left-hemispheric brain lesions (periventricular lesions [n=11] and middle cerebral artery infarctions [n=8]) by fMRI. 16/17 patients demonstrated reorganized language production, while 7/19 patients had reorganized language comprehension. Lesions to the insular cortex and the temporo-parietal junction (predominantly supramarginal gyrus) were significantly more common in patients in whom both, language production and comprehension were reorganized. These areas belong to the dorsal stream of the language network, participating in the auditory-motor integration of language. Our data suggest that the integrity of this stream might be crucial for a normal left-lateralized language development. Copyright © 2017. Published by Elsevier Inc.

Canada's Clean Air Act

International Nuclear Information System (INIS)

2006-01-01

This paper provided an outline of Canada's Clean Air Act and examined some of the regulatory changes that will occur as a result of its implementation. The Act is being introduced to strengthen the legislative basis for taking action on reducing air pollution and GHGs, and will allow the government to regulate both indoor and outdoor air pollutants and GHGs. The Act will require the Ministers of the Environment and Health to establish national air quality objectives, as well as to monitor and report on their attainment. The Canadian Environmental Protection Act will be amended to enable the government to regulate the blending of fuels and their components. The Motor Vehicle Fuel Consumption Standards Act will also be amended to enhance the government's authority to regulate vehicle fuel efficiency. The Energy Efficiency Act will also be expanded to allow the government to set energy efficiency standards and labelling requirements for a wider range of consumer and commercial products. The Act will commit to short, medium and long-term industrial air pollution targets. Regulations will be proposed for emissions from industry; on-road and off-road vehicles and engines; and consumer and commercial products. It was concluded that the Government of Canada will continue to consult with provinces, territories, industries and Canadians to set and reach targets for the reduction of both indoor and outdoor air pollutants and GHG emissions. 6 figs

77 FR 65215 - In the Matter of Licensee Identified in Attachment 1 and all Other Persons Who Obtain Safeguards...

Science.gov (United States)

2012-10-25

... section 202 of the Energy Reorganization Act of 1974 (88 Stat. 1244), any State or any political subdivision of, or any political entity within a State, any foreign government or nation or any political... existence of these requirements. Criminal and Civil Sanctions The Atomic Energy Act of 1954, as amended...

Auditory cross-modal reorganization in cochlear implant users indicates audio-visual integration.

Science.gov (United States)

Stropahl, Maren; Debener, Stefan

2017-01-01

There is clear evidence for cross-modal cortical reorganization in the auditory system of post-lingually deafened cochlear implant (CI) users. A recent report suggests that moderate sensori-neural hearing loss is already sufficient to initiate corresponding cortical changes. To what extend these changes are deprivation-induced or related to sensory recovery is still debated. Moreover, the influence of cross-modal reorganization on CI benefit is also still unclear. While reorganization during deafness may impede speech recovery, reorganization also has beneficial influences on face recognition and lip-reading. As CI users were observed to show differences in multisensory integration, the question arises if cross-modal reorganization is related to audio-visual integration skills. The current electroencephalography study investigated cortical reorganization in experienced post-lingually deafened CI users ( n  = 18), untreated mild to moderately hearing impaired individuals (n = 18) and normal hearing controls ( n  = 17). Cross-modal activation of the auditory cortex by means of EEG source localization in response to human faces and audio-visual integration, quantified with the McGurk illusion, were measured. CI users revealed stronger cross-modal activations compared to age-matched normal hearing individuals. Furthermore, CI users showed a relationship between cross-modal activation and audio-visual integration strength. This may further support a beneficial relationship between cross-modal activation and daily-life communication skills that may not be fully captured by laboratory-based speech perception tests. Interestingly, hearing impaired individuals showed behavioral and neurophysiological results that were numerically between the other two groups, and they showed a moderate relationship between cross-modal activation and the degree of hearing loss. This further supports the notion that auditory deprivation evokes a reorganization of the auditory system

Auditory cross-modal reorganization in cochlear implant users indicates audio-visual integration

Directory of Open Access Journals (Sweden)

Maren Stropahl

2017-01-01

Full Text Available There is clear evidence for cross-modal cortical reorganization in the auditory system of post-lingually deafened cochlear implant (CI users. A recent report suggests that moderate sensori-neural hearing loss is already sufficient to initiate corresponding cortical changes. To what extend these changes are deprivation-induced or related to sensory recovery is still debated. Moreover, the influence of cross-modal reorganization on CI benefit is also still unclear. While reorganization during deafness may impede speech recovery, reorganization also has beneficial influences on face recognition and lip-reading. As CI users were observed to show differences in multisensory integration, the question arises if cross-modal reorganization is related to audio-visual integration skills. The current electroencephalography study investigated cortical reorganization in experienced post-lingually deafened CI users (n = 18, untreated mild to moderately hearing impaired individuals (n = 18 and normal hearing controls (n = 17. Cross-modal activation of the auditory cortex by means of EEG source localization in response to human faces and audio-visual integration, quantified with the McGurk illusion, were measured. CI users revealed stronger cross-modal activations compared to age-matched normal hearing individuals. Furthermore, CI users showed a relationship between cross-modal activation and audio-visual integration strength. This may further support a beneficial relationship between cross-modal activation and daily-life communication skills that may not be fully captured by laboratory-based speech perception tests. Interestingly, hearing impaired individuals showed behavioral and neurophysiological results that were numerically between the other two groups, and they showed a moderate relationship between cross-modal activation and the degree of hearing loss. This further supports the notion that auditory deprivation evokes a reorganization of the

Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30.

Directory of Open Access Journals (Sweden)

Julie Carnesecchi

Full Text Available The post-menopausal decrease in estrogen circulating levels results in rapid skin deterioration pointing out to a protective effect exerted by these hormones. The identity of the skin cell type responding to estrogens is unclear as are the cellular and molecular processes they elicit. Here, we reported that lack of estrogens induces rapid re-organization of the human dermal fibroblast cytoskeleton resulting in striking cell shape change. This morphological change was accompanied by a spatial re-organization of focal adhesion and a substantial reduction of their number as evidenced by vinculin and actin co-staining. Cell morphology and cytoskeleton organization was fully restored upon 17β-estradiol (E2 addition. Treatment with specific ER antagonists and cycloheximide respectively showed that the E2 acts independently of the classical Estrogen Receptors and that cell shape change is mediated by non-genomic mechanisms. E2 treatment resulted in a rapid and transient activation of ERK1/2 but not Src or PI3K. We show that human fibroblasts express the non-classical E2 receptor GPR30 and that its agonist G-1 phenocopies the effect of E2. Inhibiting GPR30 through treatment with the G-15 antagonist or specific shRNA impaired E2 effects. Altogether, our data reveal a novel mechanism by which estrogens act on skin fibroblast by regulating cell shape through the non-classical G protein-coupled receptor GPR30 and ERK1/2 activation.

Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30.

Science.gov (United States)

Carnesecchi, Julie; Malbouyres, Marilyne; de Mets, Richard; Balland, Martial; Beauchef, Gallic; Vié, Katell; Chamot, Christophe; Lionnet, Claire; Ruggiero, Florence; Vanacker, Jean-Marc

2015-01-01

The post-menopausal decrease in estrogen circulating levels results in rapid skin deterioration pointing out to a protective effect exerted by these hormones. The identity of the skin cell type responding to estrogens is unclear as are the cellular and molecular processes they elicit. Here, we reported that lack of estrogens induces rapid re-organization of the human dermal fibroblast cytoskeleton resulting in striking cell shape change. This morphological change was accompanied by a spatial re-organization of focal adhesion and a substantial reduction of their number as evidenced by vinculin and actin co-staining. Cell morphology and cytoskeleton organization was fully restored upon 17β-estradiol (E2) addition. Treatment with specific ER antagonists and cycloheximide respectively showed that the E2 acts independently of the classical Estrogen Receptors and that cell shape change is mediated by non-genomic mechanisms. E2 treatment resulted in a rapid and transient activation of ERK1/2 but not Src or PI3K. We show that human fibroblasts express the non-classical E2 receptor GPR30 and that its agonist G-1 phenocopies the effect of E2. Inhibiting GPR30 through treatment with the G-15 antagonist or specific shRNA impaired E2 effects. Altogether, our data reveal a novel mechanism by which estrogens act on skin fibroblast by regulating cell shape through the non-classical G protein-coupled receptor GPR30 and ERK1/2 activation.

Attachment reorganization following divorce: normative processes and individual differences.

Science.gov (United States)

Sbarra, David A; Borelli, Jessica L

2018-03-21

This paper uses attachment theory as a lens for reviewing contemporary research on how adults cope with marital separation and loss. The first section of the paper discusses the process of normative attachment reorganization, or the psychology of adaptive grief responses following relationship transitions. We argue that changes two processes, in particular, can be uses to track changes in this normative reorganization process: narrative coherence and self-concept clarity. The second section of the paper suggest that individual differences in attachment anxiety and avoidance shape the variability in this normative reorganization process, largely as a result of the characteristic ways in which these styles organize emotion-regulatory tendencies. The paper closes with a series of integrative questions for future research, including a call for new studies aimed at understanding under what contexts anxiety and avoidance may be adaptive in promoting emotion recovery to separation and divorce experiences. Copyright © 2018 Elsevier Ltd. All rights reserved.

Estimating the effect of the reorganization of interactions on the adaptability of species to changing environments.

Science.gov (United States)

Cenci, Simone; Montero-Castaño, Ana; Saavedra, Serguei

2018-01-21

A major challenge in community ecology is to understand how species respond to environmental changes. Previous studies have shown that the reorganization of interactions among co-occurring species can modulate their chances to adapt to novel environmental conditions. Moreover, empirical evidence has shown that these ecological dynamics typically facilitate the persistence of groups of species rather than entire communities. However, so far, we have no systematic methodology to identify those groups of species with the highest or lowest chances to adapt to new environments through a reorganization of their interactions. Yet, this could prove extremely valuable for developing new conservation strategies. Here, we introduce a theoretical framework to estimate the effect of the reorganization of interactions on the adaptability of a group of species, within a community, to novel environmental conditions. We introduce the concept of the adaptation space of a group of species based on a feasibility analysis of a population dynamics model. We define the adaptation space of a group as the set of environmental conditions that can be made compatible with its persistence thorough the reorganization of interactions among species within the group. The larger the adaptation space of a group, the larger its likelihood to adapt to a novel environment. We show that the interactions in the community outside a group can act as structural constraints and be used to quantitatively compare the size of the adaptation space among different groups of species within a community. To test our theoretical framework, we perform a data analysis on several pairs of natural and artificially perturbed ecological communities. Overall, we find that the groups of species present in both control and perturbed communities are among the ones with the largest adaptation space. We believe that the results derived from our framework point out towards new directions to understand and estimate the

Magnetic resonance imaging research progress on brain functional reorganization after peripheral nerve injury

International Nuclear Information System (INIS)

Wang Weiwei; Liu Hanqiu

2013-01-01

In the recent years, with the development of functional magnetic resonance imaging technology the brain plasticity and functional reorganization are hot topics in the central nervous system imaging studies. Brain functional reorganization and rehabilitation after peripheral nerve injury may have certain regularity. In this paper, the progress of brain functional magnetic resonance imaging technology and its applications in the world wide clinical and experimental researches of the brain functional reorganization after peripheral nerve injury is are reviewed. (authors)

Reorganization of water and waste water management in Romania : from local to regional water governance

NARCIS (Netherlands)

Vinke-de Kruijf, Joanne; Dinica, Valentina; Augustijn, Denie C.M.

2009-01-01

Romania's drinking water and wastewater sector is currently going through a process of regionalization. This process involves a replacement of a local-focused governance structure by a regional-focused governance structure. The objective of this paper is to explore and explain this regionalization

Limitations to Plasticity of Language Network Reorganization in Localization Related Epilepsy

Science.gov (United States)

Mbwana, J.; Berl, M. M.; Ritzl, E. K.; Rosenberger, L.; Mayo, J.; Weinstein, S.; Conry, J. A.; Pearl, P. L.; Shamim, S.; Moore, E. N.; Sato, S.; Vezina, L. G.; Theodore, W. H.; Gaillard, W. D.

2009-01-01

Neural networks for processing language often are reorganized in patients with epilepsy. However, the extent and location of within and between hemisphere re-organization are not established. We studied 45 patients, all with a left hemisphere seizure focus (mean age 22.8, seizure onset 13.3), and 19 normal controls (mean age 24.8) with an fMRI…

[Hospital governance: between crisis management and implementation of public health policy].

Science.gov (United States)

Bréchat, Pierre-Henri; Antoine, Leenhardt; Mathieu-Grenouilleau, Marie-Christine; Rymer, Roland; Matisse, François; Baraille, Denis; Beaufils, Philippe

2010-01-01

The implementation of the recent act to amend the law on hospitals, patient health and territories (HPST Law) completes the reform of the organization and governance of health facilities, which was announced in 2002 by the "Hospital 2007" plan. What kind of assessments and perspectives can be considered and envisaged for these Hospital Activity Poles? We compared our experience with a review of the professional and scientific literature in order to stimulate answers to these questions for advocacy purposes prior to the Act's implementation. The hospital's cluster of activities should reinforce--not call into question the core activities and the financial stability of the facility, while respecting the contract on agreed objectives and the necessary means and resources to meet the health needs of the catchment population as well as national priorities. Although significant, but limited, successes exist, five obstacles to hospital reorganization can be identified. These include, for example: lack of delegation of management and centralization of decisions, the heterogeneity of numerous Hospital Activity Poles or problems related to timing. These obstacles may cause strain, or put the Hospital Activity Poles and the health facilities in a difficult situation with respect to their dynamics. This may show that the State and social health insurance should steer and direct public health policy and that the delegation of management roles and responsibilities to the Hospital Activity Poles should be addressed.

Manipulation of Auditory Inputs as Rehabilitation Therapy for Maladaptive Auditory Cortical Reorganization

Directory of Open Access Journals (Sweden)

Hidehiko Okamoto

2018-01-01

Full Text Available Neurophysiological and neuroimaging data suggest that the brains of not only children but also adults are reorganized based on sensory inputs and behaviors. Plastic changes in the brain are generally beneficial; however, maladaptive cortical reorganization in the auditory cortex may lead to hearing disorders such as tinnitus and hyperacusis. Recent studies attempted to noninvasively visualize pathological neural activity in the living human brain and reverse maladaptive cortical reorganization by the suitable manipulation of auditory inputs in order to alleviate detrimental auditory symptoms. The effects of the manipulation of auditory inputs on maladaptively reorganized brain were reviewed herein. The findings obtained indicate that rehabilitation therapy based on the manipulation of auditory inputs is an effective and safe approach for hearing disorders. The appropriate manipulation of sensory inputs guided by the visualization of pathological brain activities using recent neuroimaging techniques may contribute to the establishment of new clinical applications for affected individuals.

The reorganization of the Russian hydrocarbons industry: an overview

International Nuclear Information System (INIS)

Locatelli, C.

1995-01-01

The purpose of this article is to present the main guidelines for the reorganization of the Russian hydrocarbon industry. Specifically, it focuses on the economic conditions concerning the constitution of Russian oil companies in an uncertain environment. In Russia, one of the main problems is to create autonomous energy enterprises. The main conclusion is that up to now the reorganization has been essentially juridical, connected with the constitution of joint stock companies. From an economic point of view, the organizational model behind these joint stock companies is not very well defined and lacks clearly defined coordination mechanisms. (author)

Analysis of Septin Reorganization at Cytokinesis Using Polarized Fluorescence Microscopy

Directory of Open Access Journals (Sweden)

Molly McQuilken

2017-05-01

Full Text Available Septins are conserved filament-forming proteins that act in diverse cellular processes. They closely associate with membranes and, in some systems, components of the cytoskeleton. It is not well understood how filaments assemble into higher-order structures in vivo or how they are remodeled throughout the cell cycle. In the budding yeast S. cerevisiae, septins are found through most of the cell cycle in an hourglass organization at the mother-bud neck until cytokinesis when the collar splits into two rings that disassemble prior to the next cell cycle. Experiments using polarized fluorescence microscopy have suggested that septins are arranged in ordered, paired filaments in the hourglass and undergo a coordinated 90° reorientation during splitting at cytokinesis. This apparent reorganization could be due to two orthogonal populations of filaments disassembling and reassembling or being preferentially retained at cytokinesis. In support of this idea, we report a decrease in septin concentration at the mother-bud neck during cytokinesis consistent with other reports and the timing of the decrease depends on known septin regulators including the Gin4 kinase. We took a candidate-based approach to examine what factors control reorientation during splitting and used polarized fluorescence microscopy to screen mutant yeast strains deficient in septin interacting proteins. Using this method, we have linked known septin regulators to different aspects of the assembly, stability, and reorganization of septin assemblies. The data support that ring splitting requires Gin4 activity and an anillin-like protein Bud4, and normal accumulation of septins at the ring requires phosphorylation of Shs1. We found distinct regulatory requirements for septin organization in the hourglass compared to split rings. We propose that septin subpopulations can vary in their localization and assembly/disassembly behavior in a cell-cycle dependent manner at cytokinesis.

Unresolved trauma in mothers: intergenerational effects and the role of reorganization

Science.gov (United States)

Iyengar, Udita; Kim, Sohye; Martinez, Sheila; Fonagy, Peter; Strathearn, Lane

2014-01-01

A mother's unresolved trauma may interfere with her ability to sensitively respond to her infant, thus affecting the development of attachment in her own child, and potentially contributing to the intergenerational transmission of trauma. One novel construct within the Dynamic Maturational Model of Attachment and Adaptation (DMM) coding of the Adult Attachment Interview (AAI) is “reorganization,” a process whereby speakers are actively changing their understanding of past and present experiences and moving toward attachment security. We conducted a study of mothers with unresolved trauma, exploring their own attachment classification, attachment outcomes of their children, and the potential effects of reorganization on child attachment. Forty-seven first-time mothers participated in the AAI during pregnancy, and returned with their child at 11 months to assess child attachment using the Strange Situation Procedure. Mothers with and without unresolved trauma were compared. We found that mothers with unresolved trauma had insecure attachment themselves and were more likely to have infants with insecure attachment. However, the one exception was that all of the mothers with unresolved trauma who were reorganizing toward secure attachment had infants with secure attachment. These preliminary findings suggest that mothers who are reorganizing may be able to more sensitively respond to their child's cues, contributing to the development of secure attachment. While our results need to be replicated in a larger cohort, this study is the first to explore the construct of reorganization and its potential relationship with child attachment. If confirmed in future studies, it may provide clinical insight into the intergenerational transmission of insecure attachment within the context of unresolved trauma. PMID:25225490

Reorganizing the General Clinical Research Center to improve the clinical and translational research enterprise.

Science.gov (United States)

Allen, David; Ripley, Elizabeth; Coe, Antoinette; Clore, John

2013-12-01

In 2010, Virginia Commonwealth University (VCU) was granted a Clinical and Translational Science Award which prompted reorganization and expansion of their clinical research infrastructure. A case study approach is used to describe the implementation of a business and cost recovery model for clinical and translational research and the transformation of VCU's General Clinical Research Center and Clinical Trials Office to a combined Clinical Research Services entity. We outline the use of a Plan, Do, Study, Act cycle that facilitated a thoughtful transition process, which included the identification of required changes and cost recovery processes for implementation. Through this process, the VCU Center for Clinical and Translational Research improved efficiency, increased revenue recovered, reduced costs, and brought a high level of fiscal responsibility through financial reporting.

Database Reorganization in Parallel Disk Arrays with I/O Service Stealing

Science.gov (United States)

Zabback, Peter; Onyuksel, Ibrahim; Scheuermann, Peter; Weikum, Gerhard

1996-01-01

We present a model for data reorganization in parallel disk systems that is geared towards load balancing in an environment with periodic access patterns. Data reorganization is performed by disk cooling, i.e. migrating files or extents from the hottest disks to the coldest ones. We develop an approximate queueing model for determining the effective arrival rates of cooling requests and discuss its use in assessing the costs versus benefits of cooling.

DESCRIPTION OF THE ORGANIZATIONAL AND TECHNOLOGICAL PROCESSES ON THE GROUND OF THE BASIC MODEL OF THE CYCLE OF REORGANIZATION

Directory of Open Access Journals (Sweden)

Gazaryan Robert Kamoevich

2012-12-01

Full Text Available The objective of this scientific research is application of the basic model of interaction between phases of a cycle of reorganization of organizational and technological processes underway at industrial enterprises. The authors describe interactions between all six phases of the process of reorganization within the framework of the basic model of a cycle that contemplates organizational and technological processes. Engineering studies are necessary to check for the feasibility of reorganization of industrial enterprises and application of results extracted from the design documentation with a view to reorganization of production activities and construction operations. Upon completion of the decision-making process concerning the need for reorganization in accordance with the basic model of interaction between phases, there occurs restructuring that incorporates processes of design and construction. The authors have demonstrated that reorganization of the basic model cycle should be used in the design of organizational and technological processes with a view to the integrated consideration of reorganization of enterprises in order to comprehend and improve the efficiency of reorganization at each stage, as well as the control over the reorganization of a construction facility.

Inter-hemispheric language functional reorganization in low-grade glioma patients after tumour surgery.

Science.gov (United States)

Kristo, Gert; Raemaekers, Mathijs; Rutten, Geert-Jan; de Gelder, Beatrice; Ramsey, Nick F

2015-03-01

Despite many claims of functional reorganization following tumour surgery, empirical studies that investigate changes in functional activation patterns are rare. This study investigates whether functional recovery following surgical treatment in patients with a low-grade glioma in the left hemisphere is linked to inter-hemispheric reorganization. Based on literature, we hypothesized that reorganization would induce changes in the spatial pattern of activation specifically in tumour homologue brain areas in the healthy right hemisphere. An experimental group (EG) of 14 patients with a glioma in the left hemisphere near language related brain areas, and a control group of 6 patients with a glioma in the right, non-language dominant hemisphere were scanned before and after resection. In addition, an age and gender matched second control group of 18 healthy volunteers was scanned twice. A verb generation task was used to map language related areas and a novel technique was used for data analysis. Contrary to our hypothesis, we found that functional recovery following surgery of low-grade gliomas cannot be linked to functional reorganization in language homologue brain areas in the healthy, right hemisphere. Although elevated changes in the activation pattern were found in patients after surgery, these were largest in brain areas in proximity to the surgical resection, and were very similar to the spatial pattern of the brain shift following surgery. This suggests that the apparent perilesional functional reorganization is mostly caused by the brain shift as a consequence of surgery. Perilesional functional reorganization can however not be excluded. The study suggests that language recovery after transient post-surgical language deficits involves recovery of functioning of the presurgical language system. Copyright © 2014 Elsevier Ltd. All rights reserved.

Bilateral reorganization of the dentate gyrus in hippocampal sclerosis

Science.gov (United States)

Thom, M; Martinian, L; Catarino, C; Yogarajah, M; Koepp, M J.; Caboclo, L; Sisodiya, S M.

2009-01-01

Background: Hippocampal sclerosis (HS) is the most common surgical pathology associated with mesial temporal lobe epilepsy (MTLE). HS is typically characterized by mossy fiber sprouting (MFS) and reorganization of neuropeptide Y (NPY) fiber networks in the dentate gyrus. One potential cause of postoperative seizure recurrence following temporal lobe surgery may be the presence of seizure-associated bilateral hippocampal damage. We aimed to investigate patterns of hippocampal abnormalities in a postmortem series as identified by NPY and dynorphin immunohistochemistry. Methods: Analysis of dentate gyrus fiber reorganization, using dynorphin (to demonstrate MFS) and NPY immunohistochemistry, was carried out in a postmortem epilepsy series of 25 cases (age range 21–96 years). In 9 patients, previously refractory seizures had become well controlled for up to 34 years prior to death. Results: Bilateral MFS or abnormal NPY patterns were seen in 15 patients including those with bilateral symmetric, asymmetric, and unilateral HS by conventional histologic criteria. MFS and NPY reorganization was present in all classical HS cases, more variably in atypical HS, present in both MTLE and non-MTLE syndromes and with seizure histories of up to 92 years, despite seizure remission in some patients. Conclusion: Synaptic reorganization in the dentate gyrus may be a bilateral, persistent process in epilepsy. It is unlikely to be sufficient to generate seizures and more likely to represent a seizure-induced phenomenon. GLOSSARY AED = antiepileptic drug; CA1p = CA1-predominant hippocampal sclerosis; CHS = classical hippocampal sclerosis; EFG = end folium gliosis; EFS = end folium sclerosis; GCD = granule cell dispersion; GCL = granule cell layer; HS = hippocampal sclerosis; MFS = mossy fiber sprouting; MTLE = mesial temporal lobe epilepsy; NPY = neuropeptide Y; ROI = region of interest; SE = status epilepticus; TLE = temporal lobe epilepsy. PMID:19710404

What about radioactive waste management in the reorganization of the Russian nuclear industry?

International Nuclear Information System (INIS)

Krone, Juergen

2008-01-01

Even in the light of rising government revenues, the expansion of the Russian nuclear industry cannot be considered on safe grounds as far as funding is concerned. Decisions about new investments depend on proof that nuclear power is by far more profitable than investments into the development of new gas fields. For a long time, the way in which the unsolved issues of radioactive waste management were to be integrated into the reorganization of the Russian nuclear industry was an open question. Current developments demonstrate the efforts made by the Rosatom management to establish a sound basis for the sustainable management of radioactive waste. In late June 2008, the committees of the Russian parliament started deliberations of the draft legislation introduced by Rosatom about the management of radioactive waste, which includes the legal prerequisites for a sustainable national waste management system. The government-operated waste management company, FGUP 'RosRAO' (Sole Federal Government Enterprise, 'Russian Radioactive Waste'), was founded as a Rosatom subsidiary henceforth to be responsible also for the final storage of radioactive waste. Mainly recommendations of the R4.04/04, 'Strategy Definition for Russian Federation NPP Back End Radioactive Waste Management, including Draft Legislation and Institutional Framework', Tacis project were taken up, which had been elaborated by a consortium of 6 West European waste management organizations in close cooperation with Russian experts from Rosatom. The analysis conducted is described in an outline of the present situation of radioactive waste management in Russia and the recommendations derived from it. In addition, the most recent steps towards building a sustainable government-operated management system for radioactive waste of the Russian nuclear industry are explained. (orig.)

Proposal and Research Direction of Soil Mass Organic Reorganization

Science.gov (United States)

Zhang, Lu; Han, Jichang

2018-01-01

Land engineering as a new discipline has been temporarily outrageous. The proposition of soil body organic reorganization undoubtedly enriches the research content for the construction of land engineering disciplines. Soil body organic reconstruction is designed to study how to realize the ecological ecology of the land by studying the external force of nature, to study the influence of sunlight, wind and water on soil body, how to improve the soil physical structure, to further strengthen the research of biological enzymes and microbes, and promote the release and utilization of beneficial inert elements in soil body. The emerging of frontier scientific research issues with soil body organic reorganization to indicate directions for the future development of soil engineering.

Changes in Allostatic Load during workplace reorganization.

Science.gov (United States)

Carlsson, Rikke Hinge; Hansen, Åse Marie; Nielsen, Martin Lindhardt; Blønd, Morten; Netterstrøm, Bo

2017-12-01

Allostatic Load (AL) represents the strain on the body produced by repeated physiologic or allostatic responses activated during stressful situations. Several cross-sectional studies have found empirical substantiation for the relationship between impaired psychosocial work environment and high AL. The aim of this longitudinal study is to investigate changes in AL during workplace reorganization that has been shown to cause impaired psychosocial work environment. Moreover, we aim to investigate the association between changes in AL and changes in psychosocial work environment (job strain, effort-reward imbalance) and psychological distress (stress symptoms and perceived stress). A major reorganization of non-state public offices was effectuated in Denmark on 1 January 2007. In 2006 and 2008, we collected clinical and questionnaire data from 359 participants, 265 women and 94 men, employed in seven municipality or county administrations. Four municipalities and one county merged with others, while one municipality and one county remained unmerged. We calculated the AL score based on 13 physiological markers reflecting stress responses of the cardiovascular, metabolic, neuroendocrine and immune systems. We analysed changes in AL from 2006 to 2008. AL increased significantly during workplace reorganization in the whole study group but we observed only a tendency of significant increase in AL in the merger group compared with the control group. Moreover, we observed no association between the changes in AL and changes in psychosocial work environment and psychological distress. This result leaves the conclusion unclear but contributes to the limited research in this area with a longitudinal design and focus on low-risk levels and small changes in AL in healthy people as predictor of future disease. Copyright © 2017 Elsevier Inc. All rights reserved.

Burnout in health-care professionals during reorganizations and downsizing. A cohort study in nurses

Directory of Open Access Journals (Sweden)

Hall-Lord Marie-Louise

2010-06-01

Full Text Available Abstract Background Burnout is a psychological reaction triggered by interaction between personal characteristics and stress factors. Reorganizations and downsizing with increased workload imply stress for health-care professionals. This is a study of burnout in nurses during a period with two comprehensive reorganizations. Methods In this quasi-experimental retrospective cohort study, burnout was assessed in nurses with long work experience in three surveys during a 30 months' period with two comprehensive reorganizations and downsizing of a hospital unit with mostly seriously ill patients with cancer. Burnout was measured with Bergen Burnout Indicator (BBI at each survey, and "Sense of Coherence" (SOC with Antonovsky's questionnaire at the last survey. Results One man and 45 women aged 30 to 65 years were invited to the surveys. There was a significant increase in burnout during the study period, the mean increase in BBI-score was 12.5 pr year (p Conclusions There was a significant development of burnout in a group of nurses during a period with two reorganizations and downsizing. Burnout was associated with low SOC. Working with seriously ill patients with cancer has probably made the nurses exceptionally vulnerable to the stress and workload related to the reorganizations.

Balancing act: Government roles in an energy conservation network

NARCIS (Netherlands)

Peterman, A.; Kourula, A.; Levitt, R.

2014-01-01

Government-led interorganizational alliance networks present a sensible opportunity to overcome many societal challenges through collaborative governance. In particular, few researchers have studied alliance networks in the field of energy conservation in commercial buildings—a sector with unique

Sleep Strengthens but does Not Reorganize Memory Traces in a Verbal Creativity Task.

Science.gov (United States)

Landmann, Nina; Kuhn, Marion; Maier, Jonathan-Gabriel; Feige, Bernd; Spiegelhalder, Kai; Riemann, Dieter; Nissen, Christoph

2016-03-01

Sleep after learning promotes the quantitative strengthening of new memories. Less is known about the impact of sleep on the qualitative reorganization of memory content. This study tested the hypothesis that sleep facilitates both memory strengthening and reorganization as indexed by a verbal creativity task. Sixty healthy university students (30 female, 30 male, 20-30 years) were investigated in a randomized, controlled parallel-group study with three experimental groups (sleep, sleep deprivation, daytime wakefulness). At baseline, 60 items of the Compound Remote Associate (CRA) task were presented. At retest after the experimental conditions, the same items were presented again together with 20 new control items to disentangle off-line incubation from online performance effects. Sleep significantly strengthened formerly encoded memories in comparison to both wake conditions (improvement in speed of correctly resolved items). Offline reorganization was not enhanced following sleep, but was enhanced following sleep-deprivation in comparison to sleep and daytime wakefulness (solution time of previously incubated, newly solved items). Online performance did not differ between the groups (solution time of new control items). The results support the notion that sleep promotes the strengthening, but not the reorganization, of newly encoded memory traces in a verbal creativity task. Future studies are needed to further determine the impact of sleep on different types of memory reorganization, such as associative thinking, creativity and emotional memory processing, and potential clinical translations, such as the augmentation of psychotherapy through sleep interventions. © 2016 Associated Professional Sleep Societies, LLC.

Presurgical fMRI evaluation of cerebral reorganization and motor deficit in patients with tumors and vascular malformations

International Nuclear Information System (INIS)

Baciu, M.; Le Bas, J.F.; Segebarth, C.; Benabid, A.L.

2003-01-01

The aim of this fMRI study was to evaluate the motor reorganization (cerebral plasticity) and the risk of motor deficit in patients presenting with tumors and vascular malformations, within the framework of their pre-surgical planning. Functional MR imaging data was obtained from 17 patients. Ten patients (seven with tumors and three with vascular malformations) presented with motor reorganization. The results of the present study suggest that the evaluation of the cerebral reorganization is an essential step in predicting the risk of motor deficit in patients having surgical indication for treatment. Furthermore, the cerebral reorganization constitutes an important factor for surgical decision

Heterochromatin Reorganization during Early Mouse Development Requires a Single-Stranded Noncoding Transcript

Directory of Open Access Journals (Sweden)

Miguel Casanova

2013-09-01

Full Text Available The equalization of pericentric heterochromatin from distinct parental origins following fertilization is essential for genome function and development. The recent implication of noncoding transcripts in this process raises questions regarding the connection between RNA and the nuclear organization of distinct chromatin environments. Our study addresses the interrelationship between replication and transcription of the two parental pericentric heterochromatin (PHC domains and their reorganization during early embryonic development. We demonstrate that the replication of PHC is dispensable for its clustering at the late two-cell stage. In contrast, using parthenogenetic embryos, we show that pericentric transcripts are essential for this reorganization independent of the chromatin marks associated with the PHC domains. Finally, our discovery that only reverse pericentric transcripts are required for both the nuclear reorganization of PHC and development beyond the two-cell stage challenges current views on heterochromatin organization.

Task-specific reorganization of the auditory cortex in deaf humans.

Science.gov (United States)

Bola, Łukasz; Zimmermann, Maria; Mostowski, Piotr; Jednoróg, Katarzyna; Marchewka, Artur; Rutkowski, Paweł; Szwed, Marcin

2017-01-24

The principles that guide large-scale cortical reorganization remain unclear. In the blind, several visual regions preserve their task specificity; ventral visual areas, for example, become engaged in auditory and tactile object-recognition tasks. It remains open whether task-specific reorganization is unique to the visual cortex or, alternatively, whether this kind of plasticity is a general principle applying to other cortical areas. Auditory areas can become recruited for visual and tactile input in the deaf. Although nonhuman data suggest that this reorganization might be task specific, human evidence has been lacking. Here we enrolled 15 deaf and 15 hearing adults into an functional MRI experiment during which they discriminated between temporally complex sequences of stimuli (rhythms). Both deaf and hearing subjects performed the task visually, in the central visual field. In addition, hearing subjects performed the same task in the auditory modality. We found that the visual task robustly activated the auditory cortex in deaf subjects, peaking in the posterior-lateral part of high-level auditory areas. This activation pattern was strikingly similar to the pattern found in hearing subjects performing the auditory version of the task. Although performing the visual task in deaf subjects induced an increase in functional connectivity between the auditory cortex and the dorsal visual cortex, no such effect was found in hearing subjects. We conclude that in deaf humans the high-level auditory cortex switches its input modality from sound to vision but preserves its task-specific activation pattern independent of input modality. Task-specific reorganization thus might be a general principle that guides cortical plasticity in the brain.

["Hannibal ante portas" -- technical development and health care reorganization].

Science.gov (United States)

Fülesdi, Béla; Velkey, György

2011-11-20

Authors intend to analyze the impact of medical technical development on the Hungarian health care system and try to draw attention to potentially necessary measures for professional and structural health care reorganization.

Workplace Re-organization and Changes in Physiological Stress Markers

DEFF Research Database (Denmark)

Carlsson, Rikke Hinge; Hansen, Åse Marie; Kristiansen, Jesper

2014-01-01

The aim of this study was to investigate changes in physiological stress markers as a consequence of workplace reorganization. Moreover, we aimed to investigate changes in the psychosocial work environment (job strain, effortreward imbalance (ERI), in psychological distress (stress symptoms......, perceived stress) and the mediating effect of these factors on changes in physiological stress markers. We used data from a longitudinal study that studied the health consequences of a major reorganization of non-state public offices executed in Denmark on 1 January 2007. Collection of clinical...... and questionnaire data was in 2006 and 2008, and in this sub-study we included 359 participants. To reflect stress reactions of the autonomic nervous system, the endocrine system and the immune system, we included 13 physiological markers. We observed significant change in several physiological stress markers...

Bilateral reorganization of the dentate gyrus in hippocampal sclerosis: a postmortem study.

Science.gov (United States)

Thom, M; Martinian, L; Catarino, C; Yogarajah, M; Koepp, M J; Caboclo, L; Sisodiya, S M

2009-09-29

Hippocampal sclerosis (HS) is the most common surgical pathology associated with mesial temporal lobe epilepsy (MTLE). HS is typically characterized by mossy fiber sprouting (MFS) and reorganization of neuropeptide Y (NPY) fiber networks in the dentate gyrus. One potential cause of postoperative seizure recurrence following temporal lobe surgery may be the presence of seizure-associated bilateral hippocampal damage. We aimed to investigate patterns of hippocampal abnormalities in a postmortem series as identified by NPY and dynorphin immunohistochemistry. Analysis of dentate gyrus fiber reorganization, using dynorphin (to demonstrate MFS) and NPY immunohistochemistry, was carried out in a postmortem epilepsy series of 25 cases (age range 21-96 years). In 9 patients, previously refractory seizures had become well controlled for up to 34 years prior to death. Bilateral MFS or abnormal NPY patterns were seen in 15 patients including those with bilateral symmetric, asymmetric, and unilateral HS by conventional histologic criteria. MFS and NPY reorganization was present in all classical HS cases, more variably in atypical HS, present in both MTLE and non-MTLE syndromes and with seizure histories of up to 92 years, despite seizure remission in some patients. Synaptic reorganization in the dentate gyrus may be a bilateral, persistent process in epilepsy. It is unlikely to be sufficient to generate seizures and more likely to represent a seizure-induced phenomenon.

Atomic force microscopy observation of lipopolysaccharide-induced cardiomyocyte cytoskeleton reorganization.

Science.gov (United States)

Wang, Liqun; Chen, Tangting; Zhou, Xiang; Huang, Qiaobing; Jin, Chunhua

2013-08-01

We applied atomic force microscopy (AFM) to observe lipopolysaccharide (LPS)-induced intracellular cytoskeleton reorganization in primary cardiomyocytes from neonatal mouse. The nonionic detergent Triton X-100 was used to remove the membrane, soluble proteins, and organelles from the cell. The remaining cytoskeleton can then be directly visualized by AFM. Using three-dimensional technique of AFM, we were able to quantify the changes of cytoskeleton by the "density" and total "volume" of the cytoskeleton fibers. Compared to the control group, the density of cytoskeleton was remarkably decreased and the volume of cytoskeleton was significantly increased after LPS treatment, which suggests that LPS may induce the cytoskeleton reorganization and change the cardiomyocyte morphology. Copyright © 2013 Elsevier Ltd. All rights reserved.

[Diffusion of clinical governance among the Italian Local Health Units (LHUs). Analysis of the Health Surveys, the Firm Acts and the Health Plans].

Science.gov (United States)

de Belvis, A G; Biasco, A; Pelone, F; Romaniello, A; De Micco, F; Volpe, M; Ricciardi, W

2009-01-01

The objective of our research is to report on the diffusion of Clinical Governance, as introduced with the National Health Plan 2006-2008, by analysing the planning instruments set up by each Region (Regional Health Plans and Emergency Plans in regions with budget deficit), the organizational frameworks (Atti Aziendali, firm acts), and the surveys on performance and quality of healthcare among the Italian Local Health Units (Health Surveys). Our research was realized on September-December 2007 and consisted of the collection of all retrieved documents available on the web and on the online public access catalog (OPAC SBN) of the National Library Service. Futhermore, each document has been classified and analysed according to Chambers' Clinical Governance definition. A descriptive statistical and inferential analysis by applying the Chi-2 Test was performed to test the correlation between the diffusion of such a classified documents and the geographical partition of each LHU. Our results show a scarce diffusion of Firm acts (43%) and Health Surveys (24.9% of the total). Any remind to Clinical Governance instruments and methods inside each document resulted even poorer among both the organizational and performance surveys and the regional health planning frameworks, respectively.

77 FR 55182 - Reorganization of Foreign-Trade Zone 151 Under Alternative Site Framework Findlay, Ohio

Science.gov (United States)

2012-09-07

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1855] Reorganization of Foreign-Trade... option for the establishment or reorganization of zones; Whereas, the Findlay/Hancock County Chamber of Commerce, grantee of Foreign-Trade Zone 151, submitted an application to the Board (FTZ Docket 20-2012...

Experimental evidence of reorganizing landscape under changing climatic forcing

Science.gov (United States)

Singh, A.; Tejedor, A.; Zaliapin, I. V.; Reinhardt, L.; Foufoula-Georgiou, E.

2015-12-01

Quantification of the dynamics of landscape reorganization under changing climatic forcing is important to understand geomorphic transport laws under transient conditions, assess response of landscapes to external perturbations for future predictive modeling, and for interpreting past climate from stratigraphic record. For such an analysis, however, real landscape observations are limited. To this end, a series of controlled laboratory experiments on evolving landscape were conducted at the St. Anthony Falls laboratory at the University of Minnesota. High resolution elevation data at a temporal resolution of 5 mins and spatial resolution of 0.5 mm were collected as the landscape approached steady state (constant uplift and precipitation rate) and in the transient state (under the same uplift and 5 times precipitation rate). Our results reveal rapid topographic re-organization under a five-fold increase in precipitation with the fluvial regime encroaching into the previously debris dominated regime, widening and aggradation of channels and valleys, and accelerated erosion happening at hillslope scales. To better understand the initiation of the observed reorganization, we perform a connectivity and clustering analysis of the erosional and depositional events, showing strikingly different spatial patterns on landscape evolution under steady-state (SS) and transient-state (TS), even when the time under SS is renormalized to match the total volume of eroded and deposited sediment in TS. Our results suggest a regime shift in the behavior of transport processes on the landscape at the intermediate scales i.e., from supply-limited to transport-limited.

Global Dynamic Numerical Simulations of Plate Tectonic Reorganizations

Science.gov (United States)

Morra, G.; Quevedo, L.; Butterworth, N.; Matthews, K. J.; Müller, D.

2010-12-01

We use a new numerical approach for global geodynamics to investigate the origin of present global plate motion and to identify the causes of the last two global tectonic reorganizations occurred about 50 and 100 million years ago (Ma) [1]. While the 50 Ma event is the most well-known global plate-mantle event, expressed by the bend in the Hawaiian-Emperor volcanic chain, a prominent plate reorganization at about 100 Ma, although presently little studied, is clearly indicated by a major bend in the fracture zones in the Indian Ocean and by a change in Pacific plate motion [2]. Our workflow involves turning plate reconstructions into surface meshes that are subsequently employed as initial conditions for global Boundary Element numerical models. The tectonic setting that anticipates the reorganizations is processed with the software GPlates, combining the 3D mesh of the paleo-plate morphology and the reconstruction of paleo-subducted slabs, elaborated from tectonic history [3]. All our models involve the entire planetary system, are fully dynamic, have free surface, are characterized by a spectacular computational speed due to the simultaneous use of the multi-pole algorithm and the Boundary Element formulation and are limited only by the use of sharp material property variations [4]. We employ this new tool to unravel the causes of plate tectonic reorganizations, producing and comparing global plate motion with the reconstructed ones. References: [1] Torsvik, T., Müller, R.D., Van der Voo, R., Steinberger, B., and Gaina, C., 2008, Global Plate Motion Frames: Toward a unified model: Reviews in Geophysics, VOL. 46, RG3004, 44 PP., 2008 [2] Wessel, P. and Kroenke, L.W. Pacific absolute plate motion since 145 Ma: An assessment of the fixed hot spot hypothesis. Journal of Geophysical Research, Vol 113, B06101, 2008 [3] L. Quevedo, G. Morra, R. D. Mueller. Parallel Fast Multipole Boundary Element Method for Crustal Dynamics, Proceeding 9th World Congress and 4th Asian

Reorganization of a hospital catering system increases food intake in patients with inadequate intake

DEFF Research Database (Denmark)

Freil, M; Nielsen, MA; Blitz, B

2006-01-01

Background : Low food intake is a frequent problem in undernourished hospital patients. Objective: To study whether a reorganization of a hospital catering system enabling patients to choose their evening meal individually, in combination with an increase in the energy density of the food....... Conclusions: Reorganization of a hospital catering system can increase energy and protein intake and reduce waste substantially....

Governance or Governing – the Missing Link?

Directory of Open Access Journals (Sweden)

Luminiţa Maria Crăciun

2010-07-01

Full Text Available Governance and governing are two distinct concepts, but they intertwine. “Good governing” exercises good influence on development. “Good governance” supposes first a relationship of power focused on a series of reforms structured at three levels: the political – administrative level, the economic level, and the level of civil society. As this dimension is difficult to measure, the qualitative evaluation of the governing act raised the interest of the World Bank researchers, who elaborated and monitored the dynamics of a set of indicators, which includes six major dimensions of the governing. A retrospective concerning the image of governing in Romania during the period from 1996 to 2005 suggests a modest increase of the score: from -0.138 (1996 to 0.008 (2002; that was partially achieved based on the voice and responsibility index and on the political stability index, not on those that measure more directly the administrative performance or the integrity of the governing act. For a comparative study, we chose seven countries for the purposes of analysis (two new European Union member states: Romania and Bulgaria; two older member countries of the European Union: Slovenia and Latvia; three non-member states: Moldova, Ukraine, and Georgia, which reveal the quality of the governing from a comparative perspective. Corruption control completes the image created by the analyzed indicators. The mere formal accomplishment of commitments made in the pre-accession activity, doubled by recent internal evolutions, bring doubts about the credibility of the anticorruption reforms, as Romania continues to be considered the country with the highest CPI in the European Union. The pessimism of public opinion and the fact that only 34% of the Romanian people consider that the level of corruption will decrease in the following three years constitutes an alarm signal addressed to the governance, in view of the real reformation of the administration system

Theoretical Ideas of Local Government and State Government Development

Directory of Open Access Journals (Sweden)

Nikolay I. Churinov

2016-03-01

Full Text Available In this article the characteristic of a theoretical component of model of interaction of local government bodies with the central government, and also development of scientific base in the course of history is given. Relevance to this subject in the conditions of the Russian reality is added by federalism of a state system of Russia, namely a thin side in questions of competences between bodies of one hierarchy. This article, will be useful to those who deal with issues in the field of the theory of the state and the right and the municipal right. Historic facts in the form of the regulatory legal acts adopted earlier which subsequently, were a source for development of theoretical ideas of local self-government and the government are given in article.

Reorganization of Dentate Gyrus Microcircuits During Epileptogenesis

OpenAIRE

Jones, Ryan Thomas

2014-01-01

Temporal lobe epilepsy (TLE) is a form of acquired epilepsy characterized by recurrent and unprovoked seizures. TLE often develops following a precipitating neurological insult, such as traumatic brain injury, stroke, infection, prolonged febrile seizures or status epilepticus. These insults can initiate a constellation of genetic, functional, network and systems level reorganization that transforms a normal non-epileptic brain into one capable of generating recurrent and unprovoked seizures....

The Importance of Institutional Design for Distributed Local-Level Governance of Groundwater: The Case of California’s Sustainable Groundwater Management Act

Directory of Open Access Journals (Sweden)

Michael Kiparsky

2017-09-01

Full Text Available In many areas of the world, groundwater resources are increasingly stressed, and unsustainable use has become common. Where existing mechanisms for governing groundwater are ineffective or nonexistent, new ones need to be developed. Local level groundwater governance provides an intriguing alternative to top-down models, with the promise of enabling management to better match the diversity of physical and social conditions in groundwater basins. One such example is emerging in California, USA, where new state law requires new local agencies to self-organize and act to achieve sustainable groundwater management. In this article, we draw on insights from research on common pool resource management and natural resources governance to develop guidelines for institutional design for local groundwater governance, grounded in California’s developing experience. We offer nine criteria that can be used as principles or standards in the evaluation of institutional design for local level groundwater governance: scale, human capacity, funding, authority, independence, representation, participation, accountability, and transparency. We assert that local governance holds promise as an alternative to centralized governance in some settings but that its success will depend heavily on the details of its implementation. Further, for local implementation to achieve its promise, there remain important complementary roles for centralized governance. California’s developing experience with local level groundwater management in dozens of basins across the state provides a unique opportunity to test and assess the importance and influence of these criteria.

22 CFR 231.16 - Governing law.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Governing law. 231.16 Section 231.16 Foreign... EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS § 231.16 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of...

Acetic Acid Can Catalyze Succinimide Formation from Aspartic Acid Residues by a Concerted Bond Reorganization Mechanism: A Computational Study

Directory of Open Access Journals (Sweden)

Ohgi Takahashi

2015-01-01

Full Text Available Succinimide formation from aspartic acid (Asp residues is a concern in the formulation of protein drugs. Based on density functional theory calculations using Ace-Asp-Nme (Ace = acetyl, Nme = NHMe as a model compound, we propose the possibility that acetic acid (AA, which is often used in protein drug formulation for mildly acidic buffer solutions, catalyzes the succinimide formation from Asp residues by acting as a proton-transfer mediator. The proposed mechanism comprises two steps: cyclization (intramolecular addition to form a gem-diol tetrahedral intermediate and dehydration of the intermediate. Both steps are catalyzed by an AA molecule, and the first step was predicted to be rate-determining. The cyclization results from a bond formation between the amide nitrogen on the C-terminal side and the side-chain carboxyl carbon, which is part of an extensive bond reorganization (formation and breaking of single bonds and the interchange of single and double bonds occurring concertedly in a cyclic structure formed by the amide NH bond, the AA molecule and the side-chain C=O group and involving a double proton transfer. The second step also involves an AA-mediated bond reorganization. Carboxylic acids other than AA are also expected to catalyze the succinimide formation by a similar mechanism.

Acetic acid can catalyze succinimide formation from aspartic acid residues by a concerted bond reorganization mechanism: a computational study.

Science.gov (United States)

Takahashi, Ohgi; Kirikoshi, Ryota; Manabe, Noriyoshi

2015-01-12

Succinimide formation from aspartic acid (Asp) residues is a concern in the formulation of protein drugs. Based on density functional theory calculations using Ace-Asp-Nme (Ace = acetyl, Nme = NHMe) as a model compound, we propose the possibility that acetic acid (AA), which is often used in protein drug formulation for mildly acidic buffer solutions, catalyzes the succinimide formation from Asp residues by acting as a proton-transfer mediator. The proposed mechanism comprises two steps: cyclization (intramolecular addition) to form a gem-diol tetrahedral intermediate and dehydration of the intermediate. Both steps are catalyzed by an AA molecule, and the first step was predicted to be rate-determining. The cyclization results from a bond formation between the amide nitrogen on the C-terminal side and the side-chain carboxyl carbon, which is part of an extensive bond reorganization (formation and breaking of single bonds and the interchange of single and double bonds) occurring concertedly in a cyclic structure formed by the amide NH bond, the AA molecule and the side-chain C=O group and involving a double proton transfer. The second step also involves an AA-mediated bond reorganization. Carboxylic acids other than AA are also expected to catalyze the succinimide formation by a similar mechanism.

Reorganization of a hospital catering system increases food intake in patients with inadequate intake

DEFF Research Database (Denmark)

Freil, M.; Nielsen, M. A.; Biltz, C.

2006-01-01

Background: Low food intake is a frequent problem in undernourished hospital patients. Objective: To study whether a reorganization of a hospital catering system enabling patients to choose their evening meal individually, in combination with an increase in the energy density of the food, increases......: Reorganization of a hospital catering system can increase energy and protein intake and reduce waste substantially. Keywords: hospital food; nutritional risk; undernutrition...

22 CFR 230.16 - Governing law.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Governing law. 230.16 Section 230.16 Foreign... SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUB. L. 108-11-STANDARD TERMS AND CONDITIONS § 230.16 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of...

Reorganization of AECL and the future marketing program

International Nuclear Information System (INIS)

Donnelly, James

Atomic Energy of Canada Ltd. Engineering Co. has been reorganized to support the new emphasis on foreign sales of CANDU reactors. Much has been learned from reactor sales to Argentina, Korea, and Romania, but Canada needs to sell one 600 MWe reactor a year in order to avoid a decline in its nuclear industry. (LL)

75 FR 61696 - Foreign-Trade Zone 51-Duluth, MN; Application for Reorganization Under Alternative Site Framework

Science.gov (United States)

2010-10-06

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 58-2010] Foreign-Trade Zone 51--Duluth... FTZ 51, requesting authority to reorganize the zone under the alternative site framework (ASF) adopted... or reorganizing a general-purpose zone, the application would have no impact on FTZ 51's authorized...

46 CFR 391.8 - Certain corporate reorganizations and changes in partnerships, and certain transfers on death...

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Certain corporate reorganizations and changes in..., DEPARTMENT OF TRANSPORTATION REGULATIONS UNDER PUBLIC LAW 91-469 FEDERAL INCOME TAX ASPECTS OF THE CAPITAL CONSTRUCTION FUND § 391.8 Certain corporate reorganizations and changes in partnerships, and certain transfers...

Thermo-optically induced reorganizations in the main light harvesting antenna of plants. II

DEFF Research Database (Denmark)

Holm, Jens Kai; Varkonyi, Zsuzsanna; Kovacs, Laszlo

2005-01-01

We have investigated the circular dichroism spectral transients associated with the light-induced reversible reorganizations in chirally organized macrodomains of pea thylakoid membranes and loosely stacked lamellar aggregates of the main chlorophyll a/b light harvesting complexes (LHCII) isolated...... from the same membranes. These reorganizations have earlier been assigned to originate from a thermo-optic effect. According to the thermo-optic mechanism, fast local thermal transients due to dissipation of the excess excitation energy induce elementary structural changes in the close vicinity...

Emergence, institutionalization and renewal: Rhythms of adaptive governance in complex social-ecological systems.

Science.gov (United States)

Chaffin, Brian C; Gunderson, Lance H

2016-01-01

Adaptive governance provides the capacity for environmental managers and decision makers to confront variable degrees of uncertainty inherent to complex social-ecological systems. Current theoretical conceptualizations of adaptive governance represent a series of structures and processes best suited for either adapting or transforming existing environmental governance regimes towards forms flexible enough to confront rapid ecological change. As the number of empirical examples of adaptive governance described in the literature grows, the conceptual basis of adaptive governance remains largely under theorized. We argue that reconnecting adaptive governance with foundational concepts of ecological resilience-specifically Panarchy and the adaptive cycle of complex systems-highlights the importance of episodic disturbances and cross-scale interactions in triggering reorganizations in governance. By envisioning the processes of adaptive governance through the lens of Panarchy, scholars and practitioners alike will be better able to identify the emergence of adaptive governance, as well as take advantage of opportunities to institutionalize this type of governance in pursuit of sustainability outcomes. The synergistic analysis of adaptive governance and Panarchy can provide critical insight for analyzing the role of social dynamics during oscillating periods of stability and instability in social-ecological systems. A deeper understanding of the potential for cross-scale interactions to shape adaptive governance regimes may be useful as society faces the challenge of mitigating the impacts of global environmental change. Copyright © 2015 Elsevier Ltd. All rights reserved.

75 FR 73095 - Privacy Act of 1974; Report of New System of Records

Science.gov (United States)

2010-11-29

... Information Security Management Act of 2002; the Computer Fraud and Abuse Act of 1986; the E-Government Act of... Information Security Management Act of 2002; the Computer Fraud and Abuse Act of 1986; the E-Government Act of... Social Security Act (the Act) by establishing incentive payments to eligible professionals (EPs...

Forelimb training drives transient map reorganization in ipsilateral motor cortex.

Science.gov (United States)

Pruitt, David T; Schmid, Ariel N; Danaphongse, Tanya T; Flanagan, Kate E; Morrison, Robert A; Kilgard, Michael P; Rennaker, Robert L; Hays, Seth A

2016-10-15

Skilled motor training results in reorganization of contralateral motor cortex movement representations. The ipsilateral motor cortex is believed to play a role in skilled motor control, but little is known about how training influences reorganization of ipsilateral motor representations of the trained limb. To determine whether training results in reorganization of ipsilateral motor cortex maps, rats were trained to perform the isometric pull task, an automated motor task that requires skilled forelimb use. After either 3 or 6 months of training, intracortical microstimulation (ICMS) mapping was performed to document motor representations of the trained forelimb in the hemisphere ipsilateral to that limb. Motor training for 3 months resulted in a robust expansion of right forelimb representation in the right motor cortex, demonstrating that skilled motor training drives map plasticity ipsilateral to the trained limb. After 6 months of training, the right forelimb representation in the right motor cortex was significantly smaller than the representation observed in rats trained for 3 months and similar to untrained controls, consistent with a normalization of motor cortex maps. Forelimb map area was not correlated with performance on the trained task, suggesting that task performance is maintained despite normalization of cortical maps. This study provides new insights into how the ipsilateral cortex changes in response to skilled learning and may inform rehabilitative strategies to enhance cortical plasticity to support recovery after brain injury. Copyright © 2016 Elsevier B.V. All rights reserved.

Motor Cortex Reorganization in Patients with Glioma Assessed by Repeated Navigated Transcranial Magnetic Stimulation-A Longitudinal Study.

Science.gov (United States)

Barz, Anne; Noack, Anika; Baumgarten, Peter; Seifert, Volker; Forster, Marie-Therese

2018-04-01

Evidence for cerebral reorganization after resection of low-grade glioma has mainly been obtained by serial intraoperative cerebral mapping. Noninvasively collected data on cortical plasticity in tumor patients over a surgery-free period are still scarce. The present study therefore aimed at evaluating motor cortex reorganization by navigated transcranial magnetic stimulation (nTMS) in patients after perirolandic glioma surgery. nTMS was performed preoperatively and postoperatively in 20 patients, separated by 26.1 ± 24.8 months. Further nTMS mapping was conducted in 14 patients, resulting in a total follow-up period of 46.3 ± 25.4 months. Centers of gravity (CoGs) were calculated for every muscle representation area, and Euclidian distances between CoGs over time were defined. Results were compared with data from 12 healthy individuals, who underwent motor cortex mapping by nTMS in 2 sessions. Preoperatively and postoperatively pooled CoGs from the area of the dominant abductor pollicis brevis muscle and of the nondominant leg area differed significantly compared with healthy individuals (P < 0.05). Most remarkably, during the ensuing follow-up period, a reorganization of all representation areas was observed in 3 patients, and a significant shift of hand representation areas was identified in further 3 patients. Complete functional recovery of postoperative motor deficits was exclusively associated with cortical reorganization. Despite the low potential of remodeling within the somatosensory region, long-term reorganization of cortical motor function can be observed. nTMS is best suited for a noninvasive evaluation of this reorganization. Copyright © 2018 Elsevier Inc. All rights reserved.

Electronic U.S. Government Information: Policy Issues and Directions.

Science.gov (United States)

Hernon, Peter; McClure, Charles R.

1993-01-01

Provides an overview of U.S. federal information policy and its treatment of electronic information resources. Highlights include government publications; electronic government information; main providers of government information, including the Government Printing Office; the Freedom of Information Act; public access and use; information…

Drying induced upright sliding and reorganization of carbon nanotube arrays

International Nuclear Information System (INIS)

Li Qingwen; De Paula, Raymond; Zhang Xiefei; Zheng Lianxi; Arendt, Paul N; Mueller, Fred M; Zhu, Y T; Tu Yi

2006-01-01

Driven by capillary force, wet carbon nanotube (CNT) arrays have been found to reorganize into cellular structures upon drying. During the reorganization process, individual CNTs are firmly attached to the substrate and have to lie down on the substrate at cell bottoms, forming closed cells. Here we demonstrate that by modifying catalyst structures, the adhesion of CNTs to the substrate can be weakened. Upon drying such CNT arrays, CNTs may slide away from their original sites on the surface and self-assemble into cellular patterns with bottoms open. It is also found that the sliding distance of CNTs increases with array height, and drying millimetre tall arrays leads to the sliding of CNTs over a few hundred micrometres and the eventual self-assembly into discrete islands. By introducing regular vacancies in CNT arrays, CNTs may be manipulated into different patterns

GPRA (Government Performance and Results Act) and research evaluation for basic science

International Nuclear Information System (INIS)

Takahashi, Shoji

2002-08-01

The purpose of the Government Performance and Results Act of 1993 (GPRA) is to ask federal agencies for evaluating their program performance especially from cost-efficiency aspect and to report to Congress. GPRA is to hold agencies accountable for their programs by requiring that they think strategically (in most cases every 5 years) and set, measure and report goals annually. The agencies which have responsibilities for enhancing basic science like Department of Energy (DOE) and National Science Fund (NSF) are not excluded by reasons of the difficulties of economic evaluations. In Japan, based on 'the Rationalization program for the public corporations' of 2001, the research developing type corporations should make a cost-performance evaluation in addition to the conventional ones. They have same theme as US agencies struggles. The purpose of this report is to get some hints for this theme by surveying GPRA reports of DOE and NSF and analyzing related information. At present, I have to conclude although everybody accepts the necessities of socio-economic evaluations and investment criteria for basic research, studies and discussions about ways and means are still continuing even in the US. (author)

Clinical neurorehabilitation - implications of the Reorganization of Elementary Functions (REF) model

DEFF Research Database (Denmark)

Rytter, Hana Malá; Mogensen, Jesper

The REF (Reorganization of Elementary Functions) model suggests mechanisms of posttraumatic reorganization, and resolves the contradiction between localization and functional recovery. In the process of developing this model, we have reconceptualised the term ‘function’ and introduced a concept...... across situations and cognitive domains. Since novel ASs are created and selected according to situation dependent feedback mechanisms, dissimilar external conditions may call for different ASs. Consequently, therapeutically established ASs may not be adequate in the settings of daily life. Additionally......, upon the loss of a particular brain structure, the structure and networks mediating recovery will not be identical in case of different cognitive and situational demands. Therapeutically, an important implication is that rehabilitative training should include as naturalistic settings as possible....

Reorganization of the power distribution sector in India

International Nuclear Information System (INIS)

Dossani, Rafiq

2004-01-01

This paper presents the central issues for electricity-sector reform in India, as they grew out of the reform process that began in 1991, and within the context of the sector's organization, regulatory structure, and other institutional characteristics. The paper argues that India's current reform policies will not be sufficient to achieve reliable, efficient power because distribution reform has not been done. Undertaking distribution reform is a difficult path to tread because of the absence of global consensus on best practices and conflicting forces, both economic and political. The paper analyzes alternative institutional structures for reform in the distribution sector. The findings include that the objectives of coverage and efficiency may conflict, that economically efficient reorganization may be politically unachievable and that the small, municipally owned firm may be the best compromise. Since many Indian states are economically and politically diverse from each other, and include both large served and unserved areas, there is scope to vary the organizational structure depending on the state's situation. This paper provides a means to do so. The agenda for policymakers is to identify the situation in their respective states and choose a reorganization path that is the best compromise

Bilateral experimental neck pain reorganize axioscapular muscle coordination and pain sensitivity.

Science.gov (United States)

Christensen, S W; Hirata, R P; Graven-Nielsen, T

2017-04-01

Neck pain is a large clinical problem where reorganized trunk and axioscapular muscle activities have been hypothesised contributing to pain persistence and pain hypersensitivity. This study investigated the effects of bilateral experimental neck pain on trunk and axioscapular muscle function and pain sensitivity. In 25 healthy volunteers, bilateral experimental neck pain was induced in the splenius capitis muscles by hypertonic saline injections. Isotonic saline was used as control. In sitting, subjects performed slow, fast and slow-resisted unilateral arm movements before, during and after injections. Electromyography (EMG) was recorded from eight shoulder and trunk muscles bilaterally. Pressure pain thresholds (PPTs) were assessed bilaterally at the neck, head and arm. Data were normalized to the before-measures. Compared with control and post measurements, experimental neck pain caused (1) decreased EMG activity of the ipsilateral upper trapezius muscles during all but slow-resisted down movements (p neck pain reorganized axioscapular and trunk muscle activity together with local hyperalgesia and widespread hypoalgesia indicating that acute neck pain immediately affects trunk and axioscapular function which may affect both assessment and treatment. Bilateral clinical neck pain alters axioscapular muscle coordination but only effects of unilateral experimental neck pain has been investigated. Bilateral experimental neck pain causes task-dependent reorganized axioscapular and trunk muscle activity in addition to widespread decrease in pressure pain sensitivity. © 2016 European Pain Federation - EFIC®.

Nuclear Installations Act 1965

International Nuclear Information System (INIS)

1965-01-01

This Act governs all activities related to nuclear installations in the United Kingdom. It provides for the licensing procedure for nuclear installations, the duties of licensees, the competent authorities and carriers of nuclear material in respect of nuclear occurrences, as well as for the system of third party liability and compensation for nuclear damage. The Act repeals the Nuclear Installations (Licensing and Insurance) Act 1959 and the Nuclear Installations (Amendment Act) 1965 except for its Section 17(2). (NEA) [fr

To The Question Of Concept And Signs Of The Local Government

Directory of Open Access Journals (Sweden)

Levan T. Chikhladze

2015-03-01

Full Text Available In the present article author examines concept and features of the local government, provided in three legal acts, which are significant for the development of local government in the Russian legal acts. The important factor, uniting these acts is that they all are contributed to the functioning of the local government on the principles of decentralization. A special role in the formation of a decentralized local government in Russia is played by the Russian Constitution, adopted by population vote on the December 12, 1993. Particular importance plays the provisions of Article 3 and 12 of the Constitution of the Russian Federation from 1993. Provisions of the Law "On the General Principles of Local Self-Government in the Russian Federation" dated October 6, 2003 No. 131-FZ in the definition of local self-government, based on the principles of constitutional democracy. Provisions, defining the local government in the European Charter of Local Self-Government of the October 15, 1985 focus on the implementation of the relevant local government public authorities. The Charter makes an emphasis on the organs (representative government, not on the institutions (mechanisms of direct democracy. In conclusion, author underlines, that it is crucial to recognize that the municipal activities is based on the combination of local and state interests, cooperation of local governments and public authorities. Municipal authorities, by definition, cannot act outside of the general public policy management. They are endowed with the certain state powers, have a complex powers of state-imperious nature. So, the Charter make an emphasis on this fact, that local governments regulate substantial share of public affairs.

The IDC-thesaurus and its reorganization

International Nuclear Information System (INIS)

Senf, W.

1979-04-01

Final report on the IDC-Thesaurus and its reorganization. The Thesaurus set up for documentation of chemistry and its borderline areas is built up of concept sets. These concept sets unite all synonyms and are linked by concept relations reflecting the hierarchical structure of the Thesaurus. Analysis of the polyhierarchy of the Thesaurus. Composite concepts are subdivided into their broader terms of the abstraction system. These concepts as well as words with different spelling are transferred from the retrieval Thesaurus to a Thesaurus dictionary from which a file is set up for correcting the complete documentation file. (orig.) 891 WB 892 MB [de

Governance of professional nursing practice in a hospital setting: a mixed methods study.

Science.gov (United States)

dos Santos, José Luís Guedes; Erdmann, Alacoque Lorenzini

2015-01-01

To elaborate an interpretative model for the governance of professional nursing practice in a hospital setting. A mixed methods study with concurrent triangulation strategy, using data from a cross-sectional study with 106 nurses and a Grounded Theory study with 63 participants. The quantitative data were collected through the Brazilian Nursing Work Index - Revised and underwent descriptive statistical analysis. Qualitative data were obtained from interviews and analyzed through initial, selective and focused coding. Based on the results obtained with the Brazilian Nursing Work Index - Revised, it is possible to state that nurses perceived that they had autonomy, control over the environment, good relationships with physicians and organizational support for nursing governance. The governance of the professional nursing practice is based on the management of nursing care and services carried out by the nurses. To perform these tasks, nurses aim to get around the constraints of the organizational support and develop management knowledge and skills. It is important to reorganize the structures and processes of nursing governance, especially the support provided by the organization for the management practices of nurses.

Improving ICT Governance by Reorganizing Operation of ICT and Software Applications: The First Step to Outsource

Science.gov (United States)

Johansson, Björn

During recent years great attention has been paid to outsourcing as well as to the reverse, insourcing (Dibbern et al., 2004). There has been a strong focus on how the management of software applications and information and communication technology (ICT), expressed as ICT management versus ICT governance, should be carried out (Grembergen, 2004). The maintenance and operation of software applications and ICT use a lot of the resources spent on ICT in organizations today (Bearingpoint, 2004), and managers are asked to increase the business benefits of these investments (Weill & Ross, 2004). That is, they are asked to improve the usage of ICT and to develop new business critical solutions supported by ICT. It also means that investments in ICT and software applications need to be shown to be worthwhile. Basically there are two considerations to take into account with ICT usage: cost reduction and improving business value. How the governance and management of ICT and software applications are organized is important. This means that the improvement of the control of maintenance and operation may be of interest to executives of organizations. It can be stated that usage is dependent on how it is organized. So, if an increase of ICT governance is the same as having well-organized ICT resources, could this be seen as the first step in organizations striving for external provision of ICT? This question is dealt with to some degree in this paper.

Radiological Protection Act 1970

International Nuclear Information System (INIS)

1970-01-01

This Act provides for the establishment of a Radiological Protection Board to undertake research and advise on protection from radiation hazards. Its functions include provision of advice to Government departments with responsibilities in relation to protection of sectors of the community or the community as a whole against the hazards of ionizing radiation. The Act, which lays down that the Board shall replace certain departments concerned with radiation protection, repeals several Sections of the Radioactive Substances Act 1948 and the Science and Technology Act 1965. (NEA) [fr

76 FR 11764 - Sunshine Act Notice

Science.gov (United States)

2011-03-03

.... Additionally, as a part of the Board's E-Government initiative, the meeting will be presented live through... Safety Board. ACTION: Notice of public meeting. SUMMARY: Pursuant to the provisions of the Government in....dnfsb.gov ). STATUS: Open. While the Government in the Sunshine Act does not require that the scheduled...

Act of 21 February 1963, Stb. 82, concerning the release of nuclear energy and the use of radioactive materials and of devices emitting ionizing radiations (Nuclear Energy Act) as amended by the Act of 30 June 1967, Stb. 337, and the Act of 8 May 1974, Stb. 291

International Nuclear Information System (INIS)

1963-01-01

This basic Act governs all nuclear activities in the Netherlands and determines the Government's competence and the obligations of those involved in the nuclear field. It establishes definitions and sets up bodies to advise the Government in the different nuclear sectors and covers nuclear installations, fissionable materials, ores, radioactive materials, radiation-emitting devices and their licensing. It was brought into force progressively by decrees made in implementation of its provisions, which lay down detailed regulations for the activity concerned. The chapters of the Act not yet in force were brought into operation on 1 January 1970 by the Nuclear Energy Act (Implantation) Decree of 12 November 1969. (NEA) [fr

Acetylation-Dependent Chromatin Reorganization by BRDT, a Testis-Specific Bromodomain-Containing Protein

Science.gov (United States)

Pivot-Pajot, Christophe; Caron, Cécile; Govin, Jérôme; Vion, Alexandre; Rousseaux, Sophie; Khochbin, Saadi

2003-01-01

The association between histone acetylation and replacement observed during spermatogenesis prompted us to consider the testis as a source for potential factors capable of remodelling acetylated chromatin. A systematic search of data banks for open reading frames encoding testis-specific bromodomain-containing proteins focused our attention on BRDT, a testis-specific protein of unknown function containing two bromodomains. BRDT specifically binds hyperacetylated histone H4 tail depending on the integrity of both bromodomains. Moreover, in somatic cells, the ectopic expression of BRDT triggered a dramatic reorganization of the chromatin only after induction of histone hyperacetylation by trichostatin A (TSA). We then defined critical domains of BRDT involved in its activity. Both bromodomains of BRDT, as well as flanking regions, were found indispensable for its histone acetylation-dependent remodelling activity. Interestingly, we also observed that recombinant BRDT was capable of inducing reorganization of the chromatin of isolated nuclei in vitro only when the nuclei were from TSA-treated cells. This assay also allowed us to show that the action of BRDT was ATP independent, suggesting a structural role for the protein in the remodelling of acetylated chromatin. This is the first demonstration of a large-scale reorganization of acetylated chromatin induced by a specific factor. PMID:12861021

12 CFR 404.22 - Government contracts.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Government contracts. 404.22 Section 404.22 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES INFORMATION DISCLOSURE Access to Records Under the Privacy Act of 1974 § 404.22 Government contracts. (a) Approval by Assistant General Counsel for...

12 CFR 270.3 - Governing principles.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Governing principles. 270.3 Section 270.3 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) FEDERAL OPEN MARKET COMMITTEE OPEN MARKET OPERATIONS OF... Governing principles. As required by section 12A of the Federal Reserve Act, the time, character, and volume...

Dynamic reorganization of photosynthetic supercomplexes during environmental acclimation

Directory of Open Access Journals (Sweden)

Jun eMinagawa

2013-12-01

Full Text Available Plants and algae have acquired the ability to acclimate to ever-changing environments in order to survive. During photosynthesis, light energy is converted by several membrane protein supercomplexes into electrochemical energy, which is eventually used to assimilate CO2. The efficiency of photosynthesis is modulated by many environmental factors such as quality and quantity of light, temperature, drought, and CO2 concentration, among others. Accumulating evidence indicates that photosynthetic supercomplexes undergo supramolecular reorganization within a short timeframe during acclimation to an environmental change. This reorganization includes state transitions that balance the excitation of photosystem I and II by shuttling peripheral antenna proteins between the two, thermal energy dissipation that occurs at energy-quenching sites within the light-harvesting antenna generated for negative feedback when excess light is absorbed, and cyclic electron flow that is facilitated between photosystem I and the cytochrome bf complex when cells demand more ATP and/or need to activate energy dissipation. This review will highlight the recent findings regarding these environmental acclimation events in model organisms with particular attention to the unicellular green alga C. reinhardtii and with reference to the vascular plant A. thaliana, which offers a glimpse into the dynamic behavior of photosynthetic machineries in nature.

Drinking Water Management and Governance in Canada: An Innovative Plan-Do-Check-Act (PDCA) Framework for a Safe Drinking Water Supply

Science.gov (United States)

Bereskie, Ty; Rodriguez, Manuel J.; Sadiq, Rehan

2017-08-01

Drinking water management in Canada is complex, with a decentralized, three-tiered governance structure responsible for safe drinking water throughout the country. The current approach has been described as fragmented, leading to governance gaps, duplication of efforts, and an absence of accountability and enforcement. Although there have been no major waterborne disease outbreaks in Canada since 2001, a lack of performance improvement, especially in small drinking water systems, is evident. The World Health Organization water safety plan approach for drinking water management represents an alternative preventative management framework to the current conventional, reactive drinking water management strategies. This approach has seen successful implementation throughout the world and has the potential to address many of the issues with drinking water management in Canada. This paper presents a review and strengths-weaknesses-opportunities-threats analysis of drinking water management and governance in Canada at the federal, provincial/territorial, and municipal levels. Based on this analysis, a modified water safety plan (defined as the plan-do-check-act (PDCA)-WSP framework) is proposed, established from water safety plan recommendations and the principles of PDCA for continuous performance improvement. This proposed framework is designed to strengthen current drinking water management in Canada and is designed to fit within and incorporate the existing governance structure.

Drinking Water Management and Governance in Canada: An Innovative Plan-Do-Check-Act (PDCA) Framework for a Safe Drinking Water Supply.

Science.gov (United States)

Bereskie, Ty; Rodriguez, Manuel J; Sadiq, Rehan

2017-08-01

Drinking water management in Canada is complex, with a decentralized, three-tiered governance structure responsible for safe drinking water throughout the country. The current approach has been described as fragmented, leading to governance gaps, duplication of efforts, and an absence of accountability and enforcement. Although there have been no major waterborne disease outbreaks in Canada since 2001, a lack of performance improvement, especially in small drinking water systems, is evident. The World Health Organization water safety plan approach for drinking water management represents an alternative preventative management framework to the current conventional, reactive drinking water management strategies. This approach has seen successful implementation throughout the world and has the potential to address many of the issues with drinking water management in Canada. This paper presents a review and strengths-weaknesses-opportunities-threats analysis of drinking water management and governance in Canada at the federal, provincial/territorial, and municipal levels. Based on this analysis, a modified water safety plan (defined as the plan-do-check-act (PDCA)-WSP framework) is proposed, established from water safety plan recommendations and the principles of PDCA for continuous performance improvement. This proposed framework is designed to strengthen current drinking water management in Canada and is designed to fit within and incorporate the existing governance structure.

Alkem instruction: Legal relief of a Federal State against instructions under the Atomic Energy Act issued by the Federal Government

International Nuclear Information System (INIS)

Steinberg, R.

1987-01-01

The German Federal Minister for the Environment, Protection of Nature, and Reactor Safety instructed the Hesse State Minister for Economics and Technology to grant the applications filed by Alkem GmbH for a first partial permit of the construction and operation of a fuel element factory, and to grant it on the basis of a draft working document discussed between the two ministries. The new feature is the refusal of the Hesse State Minister to follow these instructions. This has given rise to a conflict between the State and Federal Governments. The article deals with one aspect of the multifaceted legal controversy, i.e., the question of the possibilities of legal relief open to a Federal State against an instruction under the Atomic Energy Act issued by the Federal Government. First, the rank of this instruction within the scope of administration on behalf of the Federal Government will be discussed. Next, the central problem of the preconditions under which an instruction may violate rights of a Federal State will be investigated. Finally, the possibilities of litigation will be briefly referred to. (orig./HP) [de

Updating Procedures Can Reorganize the Neural Circuit Supporting a Fear Memory.

Science.gov (United States)

Kwapis, Janine L; Jarome, Timothy J; Ferrara, Nicole C; Helmstetter, Fred J

2017-07-01

Established memories undergo a period of vulnerability following retrieval, a process termed 'reconsolidation.' Recent work has shown that the hypothetical process of reconsolidation is only triggered when new information is presented during retrieval, suggesting that this process may allow existing memories to be modified. Reconsolidation has received increasing attention as a possible therapeutic target for treating disorders that stem from traumatic memories, yet little is known about how this process changes the original memory. In particular, it is unknown whether reconsolidation can reorganize the neural circuit supporting an existing memory after that memory is modified with new information. Here, we show that trace fear memory undergoes a protein synthesis-dependent reconsolidation process following exposure to a single updating trial of delay conditioning. Further, this reconsolidation-dependent updating process appears to reorganize the neural circuit supporting the trace-trained memory, so that it better reflects the circuit supporting delay fear. Specifically, after a trace-to-delay update session, the amygdala is now required for extinction of the updated memory but the retrosplenial cortex is no longer required for retrieval. These results suggest that updating procedures could be used to force a complex, poorly defined memory circuit to rely on a better-defined neural circuit that may be more amenable to behavioral or pharmacological manipulation. This is the first evidence that exposure to new information can fundamentally reorganize the neural circuit supporting an existing memory.

Complete reorganization of the motor cortex of adult rats following long-term spinal cord injuries.

Science.gov (United States)

Tandon, Shashank; Kambi, Niranjan; Mohammed, Hisham; Jain, Neeraj

2013-07-01

Understanding brain reorganization following long-term spinal cord injuries is important for optimizing recoveries based on residual function as well as developing brain-controlled assistive devices. Although it has been shown that the motor cortex undergoes partial reorganization within a few weeks after peripheral and spinal cord injuries, it is not known if the motor cortex of rats is capable of large-scale reorganization after longer recovery periods. Here we determined the organization of the rat (Rattus norvegicus) motor cortex at 5 or more months after chronic lesions of the spinal cord at cervical levels using intracortical microstimulation. The results show that, in the rats with the lesions, stimulation of neurons in the de-efferented forelimb motor cortex no longer evokes movements of the forelimb. Instead, movements of the body parts in the adjacent representations, namely the whiskers and neck were evoked. In addition, at many sites, movements of the ipsilateral forelimb were observed at threshold currents. The extent of representations of the eye, jaw and tongue movements was unaltered by the lesion. Thus, large-scale reorganization of the motor cortex leads to complete filling-in of the de-efferented cortex by neighboring representations following long-term partial spinal cord injuries at cervical levels in adult rats. © 2013 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

45 CFR 503.1 - Definitions-Privacy Act.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Definitions-Privacy Act. 503.1 Section 503.1... THE UNITED STATES, DEPARTMENT OF JUSTICE RULES OF PRACTICE PRIVACY ACT AND GOVERNMENT IN THE SUNSHINE REGULATIONS Privacy Act Regulations § 503.1 Definitions—Privacy Act. For the purpose of this part: Agency...

75 FR 31440 - Privacy Act of 1974; Report of a New System of Records

Science.gov (United States)

2010-06-03

... Information Security Management Act of 2002; the Computer Fraud and Abuse Act of 1986; the E-Government Act of... Information Security Management Act of 2002; the Computer Fraud and Abuse Act of 1986; the E-Government Act of... by State law, or its fiscal agent; (3) support litigation involving the Department; (4) combat fraud...

Changes in Allostatic Load during workplace reorganization

DEFF Research Database (Denmark)

Carlsson, Rikke Hinge; Hansen, Åse Marie; Nielsen, Martin Lindhardt

2017-01-01

, effort-reward imbalance) and psychological distress (stress symptoms and perceived stress). Methods A major reorganization of non-state public offices was effectuated in Denmark on 1 January 2007. In 2006 and 2008, we collected clinical and questionnaire data from 359 participants, 265 women and 94 men...... between the changes in AL and changes in psychosocial work environment and psychological distress. Conclusions This result leaves the conclusion unclear but contributes to the limited research in this area with a longitudinal design and focus on low-risk levels and small changes in AL in healthy people...

The Sovereign Acts Doctrine in the Law of Government Contracts

Science.gov (United States)

1992-09-30

47 Ohio St. L.J. 984, 36 Def. L.J. 537 (1986). 7 concept of estoppel in government procurement.2’ A final area, which exceeds the scope of this study...position that it is possible that estoppel may run against the Government, but a case in which estoppel has been so allowed is yet to be decided. See...collateral estoppel is justified [relative to an ’equitable claim’] 5. In congressional reference cases the facts are seldom in issue.51 Instead, the question

Spatial language processing in the blind: evidence for a supramodal representation and cortical reorganization.

Directory of Open Access Journals (Sweden)

Marijn E Struiksma

Full Text Available Neuropsychological and imaging studies have shown that the left supramarginal gyrus (SMG is specifically involved in processing spatial terms (e.g. above, left of, which locate places and objects in the world. The current fMRI study focused on the nature and specificity of representing spatial language in the left SMG by combining behavioral and neuronal activation data in blind and sighted individuals. Data from the blind provide an elegant way to test the supramodal representation hypothesis, i.e. abstract codes representing spatial relations yielding no activation differences between blind and sighted. Indeed, the left SMG was activated during spatial language processing in both blind and sighted individuals implying a supramodal representation of spatial and other dimensional relations which does not require visual experience to develop. However, in the absence of vision functional reorganization of the visual cortex is known to take place. An important consideration with respect to our finding is the amount of functional reorganization during language processing in our blind participants. Therefore, the participants also performed a verb generation task. We observed that only in the blind occipital areas were activated during covert language generation. Additionally, in the first task there was functional reorganization observed for processing language with a high linguistic load. As the visual cortex was not specifically active for spatial contents in the first task, and no reorganization was observed in the SMG, the latter finding further supports the notion that the left SMG is the main node for a supramodal representation of verbal spatial relations.

Reorganizing Complex Network to Improve Large-Scale Multiagent Teamwork

Directory of Open Access Journals (Sweden)

Yang Xu

2014-01-01

Full Text Available Large-scale multiagent teamwork has been popular in various domains. Similar to human society infrastructure, agents only coordinate with some of the others, with a peer-to-peer complex network structure. Their organization has been proven as a key factor to influence their performance. To expedite team performance, we have analyzed that there are three key factors. First, complex network effects may be able to promote team performance. Second, coordination interactions coming from their sources are always trying to be routed to capable agents. Although they could be transferred across the network via different paths, their sources and sinks depend on the intrinsic nature of the team which is irrelevant to the network connections. In addition, the agents involved in the same plan often form a subteam and communicate with each other more frequently. Therefore, if the interactions between agents can be statistically recorded, we are able to set up an integrated network adjustment algorithm by combining the three key factors. Based on our abstracted teamwork simulations and the coordination statistics, we implemented the adaptive reorganization algorithm. The experimental results briefly support our design that the reorganized network is more capable of coordinating heterogeneous agents.

7 CFR 4290.470 - Prior approval of merger, consolidation, or reorganization of RBIC.

Science.gov (United States)

2010-01-01

... merge, consolidate, change form of organization (corporation, limited liability company, or limited partnership) or reorganize without the Secretary's prior written approval. Any such merger, consolidation, or...

A Structural Knowledge Representation Approach in Emergency Knowledge Reorganization

OpenAIRE

Wang, Qingquan; Rong, Lili

2007-01-01

Facing complicate problems in emergency responses, decision makers should acquire sufficient background knowledge for efficient decision-making. Emergency knowledge acquired can be a kind of special product that is transferred among emergency decision makers and functional departments. The processing of knowledge product motivates the emergency knowledge decomposition and event-oriented knowledge integration, i.e. knowledge reorganization. Supported by the semantic power of category theory, t...

Structural Reorganization of CNC in Injection-Molded CNC/PBAT Materials under Thermal Annealing.

Science.gov (United States)

Mariano, Marcos; El Kissi, Nadia; Dufresne, Alain

2016-10-04

Composite materials were prepared by extrusion and injection molding from polybutyrate adipate terephthalate (PBAT) and high aspect ratio cellulose nanocrystals (CNCs) extracted from capim dourado fibers. Three CNC contents were used, corresponding to 0.5, 1, and 2 times the theoretical percolation threshold. Small-amplitude oscillary shear (SAOS) experiments show that as the CNC content increases, a more elastic behavior is observed but no percolating network can form within the polymeric matrix as a result of the high shear rates involved during the injection-molding process. Annealing of the samples at 170 °C was performed, and the possible reorganization of the nanofiller was investigated. This reorganization was further elucidated using 2D-SAOS and creep experiments.

Differences in Brain Adaptive Functional Reorganization in Right and Left Total Brachial Plexus Injury Patients.

Science.gov (United States)

Feng, Jun-Tao; Liu, Han-Qiu; Xu, Jian-Guang; Gu, Yu-Dong; Shen, Yun-Dong

2015-09-01

Total brachial plexus avulsion injury (BPAI) results in the total functional loss of the affected limb and induces extensive brain functional reorganization. However, because the dominant hand is responsible for more cognitive-related tasks, injuries on this side induce more adaptive changes in brain function. In this article, we explored the differences in brain functional reorganization after injuries in unilateral BPAI patients. We applied resting-state functional magnetic resonance imaging scanning to 10 left and 10 right BPAI patients and 20 healthy control subjects. The amplitude of low-frequency fluctuation (ALFF), which is a resting-state index, was calculated for all patients as an indication of the functional activity level of the brain. Two-sample t-tests were performed between left BPAI patients and controls, right BPAI patients and controls, and between left and right BPAI patients. Two-sample t-tests of the ALFF values revealed that right BPAIs induced larger scale brain reorganization than did left BPAIs. Both left and right BPAIs elicited a decreased ALFF value in the right precuneus (P right BPAI patients exhibited increased ALFF values in a greater number of brain regions than left BPAI patients, including the inferior temporal gyrus, lingual gyrus, calcarine sulcus, and fusiform gyrus. Our results revealed that right BPAIs induced greater extents of brain functional reorganization than left BPAIs, which reflected the relatively more extensive adaptive process that followed injuries of the dominant hand. Copyright © 2015 Elsevier Inc. All rights reserved.

25 CFR 1000.161 - What is a self-governance compact?

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false What is a self-governance compact? 1000.161 Section 1000... EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiating A Self-Governance Compact § 1000.161 What is a self-governance compact? A self-governance compact is an executed document that affirms...

Towards improved waste management services by local government – A waste governance perspective

CSIR Research Space (South Africa)

Oelofse, Suzanna HH

2008-11-01

Full Text Available In terms of the South African Constitution (Act 108of 1996), waste management service delivery is a local government function. The Constitution further gives every person the right to an environment that is not harmful to their health or well...

Governance of professional nursing practice in a hospital setting: a mixed methods study

Directory of Open Access Journals (Sweden)

José Luís Guedes dos Santos

2015-12-01

Full Text Available Objective: to elaborate an interpretative model for the governance of professional nursing practice in a hospital setting. Method: a mixed methods study with concurrent triangulation strategy, using data from a cross-sectional study with 106 nurses and a Grounded Theory study with 63 participants. The quantitative data were collected through the Brazilian Nursing Work Index - Revised and underwent descriptive statistical analysis. Qualitative data were obtained from interviews and analyzed through initial, selective and focused coding. Results: based on the results obtained with the Brazilian Nursing Work Index - Revised, it is possible to state that nurses perceived that they had autonomy, control over the environment, good relationships with physicians and organizational support for nursing governance. The governance of the professional nursing practice is based on the management of nursing care and services carried out by the nurses. To perform these tasks, nurses aim to get around the constraints of the organizational support and develop management knowledge and skills. Conclusion: it is important to reorganize the structures and processes of nursing governance, especially the support provided by the organization for the management practices of nurses.

Governance relative to radioactive waste management - the Act of 28 June 2006

International Nuclear Information System (INIS)

Chevet, P.F.

2011-01-01

In France, the Act of 30 December 1991, relative to research on radioactive waste management, known as the 'Bataille Act' (Act No.91-1381) can be thought of as the legislative act that provided the foundations for implementation of a long-term management policy regarding high-level nuclear waste, the most radio toxic type of waste. To begin with, this involved establishing the framework for a research programme based on three possible long-term management solutions: deep geological repositories, long-term surface storage and advanced partitioning and transmutation of radioactive waste. The Act sets a deadline in 2006, the end of a period of fifteen years of research, to draw up a review and draft a new legislative framework for the future. Nonetheless, this only covered high-level radioactive waste. A table reports all the decrees taken within the framework of the Bataille Act

Nuclear industry (Finance) Act 1981

International Nuclear Information System (INIS)

1981-01-01

The purpose of the Act is to enable British Nuclear Fuels Limited to make borrowings backed by Government guarantees in order to finance its ten year investment programme. More specifically, the Act raises the financial limit applicable to British Nuclear Fuels Limited from pound 500 million to pound 1,000 million. (NEA) [fr

Reforming The Governance Of Corporate Rescue: The Enterprise Act 2002

OpenAIRE

John Armour; Rizwaan Jameel Mokal

2004-01-01

English corporate insolvency law has been reshaped by the Enterprise Act 2002. The Act was intended to ‘to facilitate company rescue and to produce better returns for creditors as a whole’. Administrative receivership, which placed control of insolvency proceedings in the hands of banks, is for most purposes being abolished. It is being replaced by a ‘streamlined’ administration procedure. Whilst it will still be possible for banks to control the appointment process, the administrator once in...

45 CFR 503.2 - General policies-Privacy Act.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false General policies-Privacy Act. 503.2 Section 503.2... THE UNITED STATES, DEPARTMENT OF JUSTICE RULES OF PRACTICE PRIVACY ACT AND GOVERNMENT IN THE SUNSHINE REGULATIONS Privacy Act Regulations § 503.2 General policies—Privacy Act. The Commission will protect the...

76 FR 22939 - Sunshine Act Meeting

Science.gov (United States)

2011-04-25

... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... Swap,'' ``Security-Based Swap Agreement,'' the regulation of mixed swaps, and books and records...

29 CFR 4.105 - The Act as amended.

Science.gov (United States)

2010-07-01

... Contract Act Introductory § 4.105 The Act as amended. (a) The provisions of the Act (see §§ 4.102-4.103... section 2(a) of the Act requires a statement in the government service contract of the rates that would be... section 4 of the Act providing for the award of service contracts for terms not more than 5 years with...

Creating Processes Associated with Providing Government Goods and Services Under the Commercial Space Launch Act at Kennedy Space Center

Science.gov (United States)

Letchworth, Janet F.

2011-01-01

Kennedy Space Center (KSC) has decided to write its agreements under the Commercial Space Launch Act (CSLA) authority to cover a broad range of categories of support that KSC could provide to our commercial partner. Our strategy was to go through the onerous process of getting the agreement in place once and allow added specificity and final cost estimates to be documented on a separate Task Order Request (TOR). This paper is written from the implementing engineering team's perspective. It describes how we developed the processes associated with getting Government support to our emerging commercial partners, such as SpaceX and reports on our success to date.

Tuning Reactivity and Electronic Properties through Ligand Reorganization within a Cerium Heterobimetallic Framework

Energy Technology Data Exchange (ETDEWEB)

Robinson, Jerome R.; Gordon, Zachary; Booth, Corwin H.; Carroll, Patrick J.; Walsh, Patrick J.; Schelter, Eric J.

2014-06-24

Cerium compounds have played vital roles in organic, inorganic, and materials chemistry due to their reversible redox chemistry between trivalent and tetravalent oxidation states. However, attempts to rationally access molecular cerium complexes in both oxidation states have been frustrated by unpredictable reactivity in cerium(III) oxidation chemistry. Such oxidation reactions are limited by steric saturation at the metal ion, which can result in high energy activation barriers for electron transfer. An alternative approach has been realized using a rare earth/alkali metal/1,1'-BINOLate (REMB) heterobimetallic framework, which uses redox-inactive metals within the secondary coordination sphere to control ligand reorganization. The rational syntheses of functionalized cerium(IV) products and a mechanistic examination of the role of ligand reorganization in cerium(III) oxidation are presented.

CORPORATE GOVERNANCE AND PERSONAL LIABILITY IN TERMS OF SECTION 424(1 OF THE COMPANIES ACT OR SECTION 64(1 OF THE CLOSE CORPORATIONS ACT

Directory of Open Access Journals (Sweden)

Johann Basson

2012-01-01

Full Text Available

ENGLISH ABSTRACT: TThe author poses the question: "In knowingly becoming a party to the conducting of corporate business, within which boundaries must I operate so as not to become personally liable for all or any of such debts or other liabilities of the corporation as the Court may direct in terms of section 424(1 of the Companies Act 61 of 1973 or section 64(1 of the Close Corporations Act 69 of 1984?"
The answer to this question may prove to be of paramount importance to members of the scientific and engineering fraternity who become involved in corporate governance, whether in a technology advisory capacity, in a managerial capacity, or otherwise.

AFRIKAANSE OPSOMMING: Die outeur stel die volgende vraag: "Indien ek wetens as 'n party betrokke raak by die bedryfvan 'n maatskappy, binne welke grense moet ek optree om persoonlike aanspreeklikheid te vermy vir al of enige van die skulde of ander verpligtinge van die maatskappy soos die Hof mag gelas ingevolge artikel 424(1 van die Maatskappywet, No. 61 van 1973 of artikel 64(1 van die Wet op Beslote Korporasies, No. 69 van 1984?"
Die antwoord op hierdie vraag mag van groot belang wees vir lede van die wetenskap- en ingenieursberoepe wat op die een of ander manier betrokke raak by die bedryf van ' n maatskappy, hetsy in 'n tegnologie-adviserende hoedanigheid, in 'n bestuurshoedanigheid ofandersins.

Making the ecosystem approach operational-Can regime shifts in ecological- and governance systems facilitate the transition?

DEFF Research Database (Denmark)

Österblom, H.; Gårdmark, A.; Bergström, L.

2010-01-01

Effectively reducing cumulative impacts on marine ecosystems requires co-evolution between science, policy and practice. Here, long-term social–ecological changes in the Baltic Sea are described, illustrating how the process of making the ecosystem approach operational in a large marine ecosystem...... stimulating innovations and re-organizing governance structures at drainage basin level to the Baltic Sea catchment as a whole. Experimentation and innovation at local to the regional levels is critical for a transition to ecosystem-based management. Establishing science-based learning platforms at sub...

25 CFR 23.21 - Noncompetitive tribal government grants.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Noncompetitive tribal government grants. 23.21 Section 23... ACT Grants to Indian Tribes for Title II Indian Child and Family Service Programs § 23.21 Noncompetitive tribal government grants. (a) Grant application information and technical assistance. Information...

Anthropogenic Reorganization of Critical Zone in Intensively Managed Landscapes

Science.gov (United States)

Kumar, P.; Anders, A. M.; Bettis, E. A., III; Blair, N. E.; Filley, T. R.; Grimley, D. A.; Le, P. V.; Lin, H.; Lin, Y. F. F.; Keefer, D. A.; Keefer, L. L.; Muste, M.; Packman, A. I.; Papanicolaou, T.; Rhoads, B. L.; Richardson, M.; Schnoebelen, D. J.; Stumpf, A.; Ward, A. S.; Wilson, C. G.; Woo, D.; Yan, Q.; Goodwell, A. E.

2016-12-01

Intensification of industrial agricultural practices has resulted in some of the most profound global impacts in the Anthropocene. These include eutrophication of lakes, rivers, and oceans from nutrient loading, degradation of arable land from the loss of fertile organic soils through erosion, and loss and degradation of soil organic matter from mechanical impacts on the soil, among others. As we prepare to feed additional 2 billion people by 2050 along with the emerging practices of farming for bioenergy production, these practices will intensify further whose goal is to overcome bio-geo-physical rate limitations and rate limiting states to enhance agricultural productivity. These rate-enhancing efforts generally target the fast response production processes, creating an imbalance with the slower assimilative processes in the Critical Zone that cascade through complex inter-dependencies across carbon, soil, water, nutrient and ecological systems. These imbalances modify stores and create gradients for flux, which over time reorganize the landscape, both in structure and function. In this presentation we show how these reorganizations are occurring in the Critical Zone of intensively managed landscapes, and argue that an integrated understanding of such profound changes are necessary for developing sustainable solutions for maintaining agricultural productivity and mitigating agriculture based environmental impacts.

Reorganization energy upon charging a single molecule on an insulator measured by atomic force microscopy

Science.gov (United States)

Fatayer, Shadi; Schuler, Bruno; Steurer, Wolfram; Scivetti, Ivan; Repp, Jascha; Gross, Leo; Persson, Mats; Meyer, Gerhard

2018-05-01

Intermolecular single-electron transfer on electrically insulating films is a key process in molecular electronics1-4 and an important example of a redox reaction5,6. Electron-transfer rates in molecular systems depend on a few fundamental parameters, such as interadsorbate distance, temperature and, in particular, the Marcus reorganization energy7. This crucial parameter is the energy gain that results from the distortion of the equilibrium nuclear geometry in the molecule and its environment on charging8,9. The substrate, especially ionic films10, can have an important influence on the reorganization energy11,12. Reorganization energies are measured in electrochemistry13 as well as with optical14,15 and photoemission spectroscopies16,17, but not at the single-molecule limit and nor on insulating surfaces. Atomic force microscopy (AFM), with single-charge sensitivity18-22, atomic-scale spatial resolution20 and operable on insulating films, overcomes these challenges. Here, we investigate redox reactions of single naphthalocyanine (NPc) molecules on multilayered NaCl films. Employing the atomic force microscope as an ultralow current meter allows us to measure the differential conductance related to transitions between two charge states in both directions. Thereby, the reorganization energy of NPc on NaCl is determined as (0.8 ± 0.2) eV, and density functional theory (DFT) calculations provide the atomistic picture of the nuclear relaxations on charging. Our approach presents a route to perform tunnelling spectroscopy of single adsorbates on insulating substrates and provides insight into single-electron intermolecular transport.

75 FR 66811 - Sunshine Act Meeting

Science.gov (United States)

2010-10-29

... Law 111-203, to prohibit fraud, manipulation, and deception in connection with security-based swaps. 3... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange...

75 FR 3948 - Sunshine Act Meeting

Science.gov (United States)

2010-01-25

... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... matters relating to climate change. At times, changes in Commission priorities require alterations in the...

78 FR 26667 - Sunshine Act Meeting

Science.gov (United States)

2013-05-07

... first panel will examine issues in connection with the possibility of developing a credit rating... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange...

isk governance: Experience of Islamic banks

Directory of Open Access Journals (Sweden)

Siti Rohaya Mat Rahim

2015-05-01

Full Text Available Risk governance has evolved tremendously in the banking industry. Risk governance recommends the imperative roles of Chief Risk Officer (CRO to oversee risk. This study explores risk governance influence over the Islamic banks performances. Multivariate analysis techniques measure simultaneously via Structural Equation Modelling (SEM. This study employed cross-sectional sample of 200 Islamic banks across 21 countries for the year 2014. To examine risk governance and Islamic banks performance, the study captures seventeen variables developed from risk management and corporate governance (ROA, ROE, Profit Margin, CRO, Shariah committee member, CEO, board size, remuneration meeting, credit rating, external audit, accounting standard, loan loss provision, capital adequacy ratio, total deposit ratio, GDP, central bank lending rate and inflation. The simulation result reveals, risk governance act as mediating variables towards Islamic banks performance. This study has practical and significance contribution for Islamic banks to understand risk governance, aligning with the fundamental risk management and corporate governance

Nuclear reorganization barriers to electron transfer

International Nuclear Information System (INIS)

Sutin, N.; Brunschwig, B.S.; Creutz, C.; Winkler, J.R.

1988-01-01

The nuclear barrier to electron transfer arises from the need for reorganization of intramolecular and solvent internuclear distances prior to electron transfer. For reactions with relatively small driving force (''normal'' free-energy region) the nuclear factors and rates increase as intrinsic inner-shell and outer-shell barriers decrease; this is illustrated by data for transition metal complexes in their ground electronic states. By contrast, in the inverted free-energy region, rates and nuclear factors decrease with decreasing ''intrinsic'' barriers; this is illustrated by data for the decay of charge-transfer excited states. Several approaches to the evaluation of the outer-shell barrier are explored in an investigation of the distance dependence of the nuclear factor in intramolecular electron-transfer processes. 39 refs., 14 figs., 3 tabs

Kinetics of structural reorganizations in multilamellarphotosynthetic membranes monitored by small-angle neutronscattering

DEFF Research Database (Denmark)

Nagy, Gergely; Kovacs, Laszlo; Unnep, Renata

2013-01-01

and in unicellular organisms, we discuss the advantages and technical and methodological limitations of timeresolved SANS. We present a detailed and more systematical investigation of the kinetics of light-induced structural reorganizations in isolated spinach thylakoid membranes, which show how changes...

Mirror therapy in lower limb amputees. A look beyond primary motor cortex reorganization

Energy Technology Data Exchange (ETDEWEB)

Seidel, S.; Essmeister, M.; Sycha, T.; Auff, E. [Vienna Medical Univ. (Austria). Dept. of Neurology; Kasprian, G.; Furtner, J.; Schoepf, V.; Prayer, D. [Vienna Medical Univ. (Austria). Dept. of Neuroradiology

2011-11-15

Phantom pain in upper limb amputees is associated with the extent of reorganization in the primary sensorimotor cortex. Mirror visual feedback therapy has been shown to improve phantom pain. We investigated the extent of cortical reorganization in lower limb amputees and changes in neural activity induced by mirror therapy. Eight lower limb amputees underwent 12 sessions of MVFT and functional magnetic resonance imaging (fMRI) of the brain before the first and after the last MVFT session. FMRI sessions consisted of two runs in which subjects were instructed to perform repetitive movement of the healthy and phantom ankle. Before MVFT, the mean phantom pain intensity was 4.6 {+-} 3.1 on a visual analog scale and decreased to 1.8 {+-} 1.7 (p = 0.04). We did not observe a consistent pattern of cortical activation in primary sensorimotor areas during phantom limb movements. Following MVFT, increased activity was obtained in the right orbitofrontal cortex during phantom ankle movements. Comparison of cortical activity during movements of the phantom ankle and the intact ankle showed significantly higher activity in the left inferior frontal cortex (pars triangularis). These results question the known association between phantom pain and primary sensorimotor reorganization and propose reorganizational changes involving multiple cortical areas in lower limb amputees. Finally, reduction of phantom pain after mirror visual feedback therapy was associated with increased prefrontal cortical activity during phantom ankle movements. (orig.)

Microstructure of transcallosal motor fibers reflects type of cortical (re-)organization in congenital hemiparesis.

Science.gov (United States)

Juenger, Hendrik; Koerte, Inga K; Muehlmann, Marc; Mayinger, Michael; Mall, Volker; Krägeloh-Mann, Ingeborg; Shenton, Martha E; Berweck, Steffen; Staudt, Martin; Heinen, Florian

2014-11-01

Early unilateral brain lesions can lead to different types of corticospinal (re-)organization of motor networks. In one group of patients, the contralesional hemisphere exerts motor control not only over the contralateral non-paretic hand but also over the (ipsilateral) paretic hand, as the primary motor cortex is (re-)organized in the contralesional hemisphere. Another group of patients with early unilateral lesions shows "normal" contralateral motor projections starting in the lesioned hemisphere. We investigated how these different patterns of cortical (re-)organization affect interhemispheric transcallosal connectivity in patients with congenital hemiparesis. Eight patients with ipsilateral motor projections (group IPSI) versus 7 patients with contralateral motor projections (group CONTRA) underwent magnetic resonance diffusion tensor imaging (DTI). The corpus callosum (CC) was subdivided in 5 areas (I-V) in the mid-sagittal slice and volumetric information. The following diffusion parameters were calculated: fractional anisotropy (FA), trace, radial diffusivity (RD), and axial diffusivity (AD). DTI revealed significantly lower FA, increased trace and RD for group IPSI compared to group CONTRA in area III of the corpus callosum, where transcallosal motor fibers cross the CC. In the directly neighboring area IV, where transcallosal somatosensory fibers cross the CC, no differences were found for these DTI parameters between IPSI and CONTRA. Volume of callosal subsections showed significant differences for area II (connecting premotor cortices) and III, where group IPSI had lower volume. The results of this study demonstrate that the callosal microstructure in patients with congenital hemiparesis reflects the type of cortical (re-)organization. Early lesions disrupting corticospinal motor projections to the paretic hand consecutively affect the development or maintenance of transcallosal motor fibers. Copyright © 2014 European Paediatric Neurology Society

Governing Academic Medical Center Systems: Evaluating and Choosing Among Alternative Governance Approaches.

Science.gov (United States)

Chari, Ramya; O'Hanlon, Claire; Chen, Peggy; Leuschner, Kristin; Nelson, Christopher

2018-02-01

The ability of academic medical centers (AMCs) to fulfill their triple mission of patient care, medical education, and research is increasingly being threatened by rising financial pressures and resource constraints. Many AMCs are, therefore, looking to expand into academic medical systems, increasing their scale through consolidation or affiliation with other health care systems. As clinical operations grow, though, the need for effective governance becomes even more critical to ensure that the business of patient care does not compromise the rest of the triple mission. Multi-AMC systems, a model in which multiple AMCs are governed by a single body, pose a particular challenge in balancing unity with the needs of component AMCs, and therefore offer lessons for designing AMC governance approaches. This article describes the development and application of a set of criteria to evaluate governance options for one multi-AMC system-the University of California (UC) and its five AMCs. Based on a literature review and key informant interviews, the authors identified criteria for evaluating governance approaches (structures and processes), assessed current governance approaches using the criteria, identified alternative governance options, and assessed each option using the identified criteria. The assessment aided UC in streamlining governance operations to enhance their ability to respond efficiently to change and to act collectively. Although designed for UC and a multi-AMC model, the criteria may provide a systematic way for any AMC to assess the strengths and weaknesses of its governance approaches.

77 FR 1095 - Sunshine Act Meeting

Science.gov (United States)

2012-01-09

... provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... 2012 budget of the Public Company Accounting Oversight Board and will consider the related annual accounting support fee for the Board under Section 109 of the Sarbanes-Oxley Act of 2002. Commissioner...

Helping Teams Work: Lessons Learned from the University of Arizona Library Reorganization.

Science.gov (United States)

Diaz, Joseph R.; Pintozzi, Chestalene

1999-01-01

Describes library reorganization at the University of Arizona resulting from fiscal challenges and the need for current technology. Highlights include: the restructuring process and customer focus; team functioning and the learning organization, including training issues, communication, empowerment, and evaluation/assessment; current challenges,…

75 FR 75187 - Sunshine Act Meeting

Science.gov (United States)

2010-12-02

... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange.... Elizabeth M. Murphy, Secretary. [FR Doc. 2010-30407 Filed 11-30-10; 4:15 pm] BILLING CODE 8011-01-P ...

Reorganizing Care With the Implementation of Electronic Medical Records: A Time-Motion Study in the PICU.

Science.gov (United States)

Roumeliotis, Nadia; Parisien, Geneviève; Charette, Sylvie; Arpin, Elizabeth; Brunet, Fabrice; Jouvet, Philippe

2018-04-01

To assess caregivers' patient care time before and after the implementation of a reorganization of care plan with electronic medical records. A prospective, observational, time-motion study. A level 3 PICU. Nurses and orderlies caring for intubated patients during an 8-hour work shift before (2008-2009) and after (2016) implementation of reorganization of care in 2013. The reorganization plan included improved telecommunication for healthcare workers, increased tasks delegated to orderlies, and an ICU-specific electronic medical record (Intellispace Critical Care and Anesthesia information system, Philips Healthcare). Time spent completing various work tasks was recorded by direct observation, and proportion of time in tasks was compared for each study period. A total of 153.7 hours was observed from 22 nurses and 14 orderlies. There was no significant difference in the proportion of nursing patient care time before (68.8% [interquartile range, 48-72%]) and after (55% [interquartile range, 51-57%]) (p = 0.11) the reorganization with electronic medical record. Direct patient care task time for nurses was increased from 27.0% (interquartile range, 30-37%) before to 34.7% (interquartile range, 33-75%) (p = 0.336) after, and indirect patient care tasks decreased from 33.6% (interquartile range, 23-41%) to 18.6% (interquartile range, 16-22%) (p = 0.036). Documentation time significantly increased from 14.5% (interquartile range, 12-22%) to 26.2% (interquartile range, 23-28%) (p = 0.032). Nursing productivity ratio improved from 28.3 to 26.0. A survey revealed that nursing staff was satisfied with the electronic medical record, although there was a concern for the maintenance of oral communication in the unit. The reorganization of care with the implementation of an ICU-specific electronic medical record in the PICU did not change total patient care provided but improved nursing productivity, resulting in improved efficiency. Documentation time was significantly

Therapy induces widespread reorganization of motor cortex after complete spinal transection that supports motor recovery.

Science.gov (United States)

Ganzer, Patrick D; Manohar, Anitha; Shumsky, Jed S; Moxon, Karen A

2016-05-01

Reorganization of the somatosensory system and its relationship to functional recovery after spinal cord injury (SCI) has been well studied. However, little is known about the impact of SCI on organization of the motor system. Recent studies suggest that step-training paradigms in combination with spinal stimulation, either electrically or through pharmacology, are more effective than step training alone at inducing recovery and that reorganization of descending corticospinal circuits is necessary. However, simpler, passive exercise combined with pharmacotherapy has also shown functional improvement after SCI and reorganization of, at least, the sensory cortex. In this study we assessed the effect of passive exercise and serotonergic (5-HT) pharmacological therapies on behavioral recovery and organization of the motor cortex. We compared the effects of passive hindlimb bike exercise to bike exercise combined with daily injections of 5-HT agonists in a rat model of complete mid-thoracic transection. 5-HT pharmacotherapy combined with bike exercise allowed the animals to achieve unassisted weight support in the open field. This combination of therapies also produced extensive expansion of the axial trunk motor cortex into the deafferented hindlimb motor cortex and, surprisingly, reorganization within the caudal and even the rostral forelimb motor cortex areas. The extent of the axial trunk expansion was correlated to improvement in behavioral recovery of hindlimbs during open field locomotion, including weight support. From a translational perspective, these data suggest a rationale for developing and optimizing cost-effective, non-invasive, pharmacological and passive exercise regimes to promote plasticity that supports restoration of movement after spinal cord injury. Copyright © 2016. Published by Elsevier Inc.

78 FR 73438 - Reorganization of Sector Baltimore and Hampton Roads; Conforming Amendments

Science.gov (United States)

2013-12-06

...-0251] RIN 1625-ZA32 Reorganization of Sector Baltimore and Hampton Roads; Conforming Amendments AGENCY... Roads' Marine Inspection Zone and Captain of the Port Zones. These conforming amendments are necessary... lines separating Sector Baltimore and Sector Hampton Roads. See Operating Facility Change Order (OFCO...

Reorganization in Secondary Somatosensory Cortex in Chronic Low Back Pain Patients.

Science.gov (United States)

Hotz-Boendermaker, Sabina; Marcar, Valentine L; Meier, Michael L; Boendermaker, Bart; Humphreys, Barry K

2016-06-01

A cross-sectional comparative study between chronic low back pain (CLBP) patients and healthy control subjects. The aim of this study was to investigate reorganization in the sensory cortex by comparing cortical activity due to mechanosensory stimulation of the lumbar spine in CLBP patients versus a control group by using functional magnetic resonance imaging (fMRI). LBP is now the number 1 condition across the world in terms of years living with a disability. There is growing evidence that maladaptive changes in the processing of sensory input by the central nervous system are central to understanding chronic (back) pain. Nonpainful, posterior-anterior (PA) movement pressure was applied manually to lumbar vertebrae at L1, L3, and L5 in 13 healthy subjects and 13 CLBP patients. The manual pressure (30 N) was monitored and controlled using sensors. A randomized stimulation protocol was used consisting of 51 pressure stimuli of 5 seconds duration. fMRI data analysis was performed for the group activation within the primary and secondary sensory cortices (S1 and S2, respectively) and the representation of the individual vertebrae was extracted and statistically analyzed. Nonpainful PA pressure revealed no cortical reorganization in S1. In contrast, the extent of S2 activation in the CLBP group was significantly reduced in both hemispheres. In the control group, a somatotopy was identified for the lumbar vertebrae between L1 and L3, respectively, and L5 in S2 of the right hemisphere. Most importantly, a blurring of the somatotopic representation of the lumbar spine in S2 was observed in the patient group. Together, these maladaptive changes suggest a reorganization of higher-order processing for sensory information in CLBP patients that might have implications for a decreased sensory acuity, also related to body perception and subsequent altered functioning of the lumbar spine. 2.

31 CFR 800.214 - Foreign government-controlled transaction.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Foreign government-controlled transaction. 800.214 Section 800.214 Money and Finance: Treasury Regulations Relating to Money and Finance... control of a U.S. business by a foreign government or a person controlled by or acting on behalf of a...

Cross-Modal Functional Reorganization of Visual and Auditory Cortex in Adult Cochlear Implant Users Identified with fNIRS.

Science.gov (United States)

Chen, Ling-Chia; Sandmann, Pascale; Thorne, Jeremy D; Bleichner, Martin G; Debener, Stefan

2016-01-01

Cochlear implant (CI) users show higher auditory-evoked activations in visual cortex and higher visual-evoked activation in auditory cortex compared to normal hearing (NH) controls, reflecting functional reorganization of both visual and auditory modalities. Visual-evoked activation in auditory cortex is a maladaptive functional reorganization whereas auditory-evoked activation in visual cortex is beneficial for speech recognition in CI users. We investigated their joint influence on CI users' speech recognition, by testing 20 postlingually deafened CI users and 20 NH controls with functional near-infrared spectroscopy (fNIRS). Optodes were placed over occipital and temporal areas to measure visual and auditory responses when presenting visual checkerboard and auditory word stimuli. Higher cross-modal activations were confirmed in both auditory and visual cortex for CI users compared to NH controls, demonstrating that functional reorganization of both auditory and visual cortex can be identified with fNIRS. Additionally, the combined reorganization of auditory and visual cortex was found to be associated with speech recognition performance. Speech performance was good as long as the beneficial auditory-evoked activation in visual cortex was higher than the visual-evoked activation in the auditory cortex. These results indicate the importance of considering cross-modal activations in both visual and auditory cortex for potential clinical outcome estimation.

Cross-Modal Functional Reorganization of Visual and Auditory Cortex in Adult Cochlear Implant Users Identified with fNIRS

Directory of Open Access Journals (Sweden)

Ling-Chia Chen

2016-01-01

Full Text Available Cochlear implant (CI users show higher auditory-evoked activations in visual cortex and higher visual-evoked activation in auditory cortex compared to normal hearing (NH controls, reflecting functional reorganization of both visual and auditory modalities. Visual-evoked activation in auditory cortex is a maladaptive functional reorganization whereas auditory-evoked activation in visual cortex is beneficial for speech recognition in CI users. We investigated their joint influence on CI users’ speech recognition, by testing 20 postlingually deafened CI users and 20 NH controls with functional near-infrared spectroscopy (fNIRS. Optodes were placed over occipital and temporal areas to measure visual and auditory responses when presenting visual checkerboard and auditory word stimuli. Higher cross-modal activations were confirmed in both auditory and visual cortex for CI users compared to NH controls, demonstrating that functional reorganization of both auditory and visual cortex can be identified with fNIRS. Additionally, the combined reorganization of auditory and visual cortex was found to be associated with speech recognition performance. Speech performance was good as long as the beneficial auditory-evoked activation in visual cortex was higher than the visual-evoked activation in the auditory cortex. These results indicate the importance of considering cross-modal activations in both visual and auditory cortex for potential clinical outcome estimation.

Airway Clearance Techniques (ACTs)

Medline Plus

Full Text Available ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements ... Board of Trustees Our Leadership Careers Reports and Financials Contact Us Governance and Policies What is CF? ...

Photovoltaic industry, towards a reorganization

International Nuclear Information System (INIS)

Houot, G.

2011-01-01

During the first semester 2011 the sales of photovoltaic equipment have dropped unexpectedly, certainly due to the harsh winter in Europe and the reduction of the policy of financial incentives in some countries. This drop in demand has triggered such a drop in prices that some manufacturers face financial difficulties, for instance the American Evergreen Solar was declared bankrupt in mid august 2011. Today the production of solar panels exceeds the demand. The third term of 2011 shows an improvement but the sector will not escape a reorganization: there are too many manufacturers, some will disappear, other will merge, the biggest will stay. Some economists see the future market divided into 2 sectors: one sector dedicated to the mass production of classical solar panels at very low cost, this sector will be occupied mainly by Chinese companies and another sector demanding a more specialized know-how will be driven by American, Japanese and European companies. (A.C.)

Aspects of Land Administration in the Context of Good Governance

Directory of Open Access Journals (Sweden)

G Pienaar

2009-07-01

Full Text Available Recent international developments have emphasised the importance of good governance in land administration. Good governance practices are inter alia predictable, open and enlightened policy-making; accountable and transparent processes; a professional ethos that combats corruption, bias, nepotism and personal gain; and strict financial control and management of funding. This paper explores aspects of land administration where public funding and interests necessitate the application of good governance practices. The South African land reform programme is divided in three sub-programmes, namely land restitution, land redistribution and tenure reform. Land reform is a vast subject, based on policy, legislation and case law. Therefore it is impossible to deal with good governance principles over the wide spectrum of land reform. Special attention is however given to the land restitution programme in terms of the Restitution of Land Rights Act 22 of 1994 and tenure reform in the rural areas by means of the Communal Land Rights Act 11 of 2004. The purpose is not to formulate a blueprint for good governance or to indicate which good governance principles will solve all or most of the land tenure problems. It is rather an effort to indicate that policies and procedures to improve good governance in some aspects of land reform are urgently needed and should be explored further. The three land tenure programmes have been introduced with some degree of success. Legislation promulgated in terms of these programmes, especially the Restitution of Land Rights Act and the Communal Land Rights Act, is extensive and far-reaching. However, many legislative measures are either impractical due to financial constraints and lack of capacity of the Department of Land Affairs, or are not based on sufficient participation by local communities. Land administration should furthermore be planned and executed in the context of global good governance practices. This includes

Aging causes a reorganization of cortical and spinal control of posture

Directory of Open Access Journals (Sweden)

Selma ePapegaaij

2014-03-01

Full Text Available Classical studies in animal preparations suggest a strong role for spinal control of posture. In young adults it is now established that the cerebral cortex contributes to postural control of unperturbed and perturbed standing. The age-related degeneration and accompanying functional changes in the brain, reported so far mainly in conjunction with simple manual motor tasks, may also affect the mechanisms that control complex motor tasks involving posture. This review outlines the age-related structural and functional changes at spinal and cortical levels and provides a mechanistic analysis of how such changes may be linked to the behaviorally manifest postural deficits in old adults. The emerging picture is that the age-related reorganization in motor control during voluntary tasks, characterized by differential modulation of spinal reflexes, greater cortical activation and cortical disinhibition, is also present during postural tasks. We discuss the possibility that this reorganization underlies the increased coactivation and dual task interference reported in elderly. Finally, we propose a model for future studies to unravel the structure-function-behavior relations in postural control and aging.

The buck stops here.

Science.gov (United States)

Shinkman, R

1998-08-03

As Allegheny Health, Education and Research Foundation muddles through its high-profile bankruptcy reorganization, the spotlight of public scrutiny is now shining brightly on the system's board members, who were supposed to act as guardians of the not-for-profit system. "When things fall apart, the board members usually take the heat," says one governance expert. "And they should take the heat, since they are the final buffer."

25 CFR 1000.429 - What statutes and regulations govern resolution of disputes concerning signed AFAs or compacts...

Science.gov (United States)

2010-04-01

... UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Appeals § 1000.429 What statutes and regulations govern resolution of disputes concerning signed AFAs or... 25 Indians 2 2010-04-01 2010-04-01 false What statutes and regulations govern resolution of...

The role of the tunneling matrix element and nuclear reorganization in the design of quantum-dot cellular automata molecules

Science.gov (United States)

Henry, Jackson; Blair, Enrique P.

2018-02-01

Mixed-valence molecules provide an implementation for a high-speed, energy-efficient paradigm for classical computing known as quantum-dot cellular automata (QCA). The primitive device in QCA is a cell, a structure with multiple quantum dots and a few mobile charges. A single mixed-valence molecule can function as a cell, with redox centers providing quantum dots. The charge configuration of a molecule encodes binary information, and device switching occurs via intramolecular electron transfer between dots. Arrays of molecular cells adsorbed onto a substrate form QCA logic. Individual cells in the array are coupled locally via the electrostatic electric field. This device networking enables general-purpose computing. Here, a quantum model of a two-dot molecule is built in which the two-state electronic system is coupled to the dominant nuclear vibrational mode via a reorganization energy. This model is used to explore the effects of the electronic inter-dot tunneling (coupling) matrix element and the reorganization energy on device switching. A semi-classical reduction of the model also is made to investigate the competition between field-driven device switching and the electron-vibrational self-trapping. A strong electron-vibrational coupling (high reorganization energy) gives rise to self-trapping, which inhibits the molecule's ability to switch. Nonetheless, there remains an expansive area in the tunneling-reorganization phase space where molecules can support adequate tunneling. Thus, the relationship between the tunneling matrix element and the reorganization energy affords significant leeway in the design of molecules viable for QCA applications.

Mirror therapy in lower limb amputees. A look beyond primary motor cortex reorganization

International Nuclear Information System (INIS)

Seidel, S.; Essmeister, M.; Sycha, T.; Auff, E.; Kasprian, G.; Furtner, J.; Schoepf, V.; Prayer, D.

2011-01-01

Phantom pain in upper limb amputees is associated with the extent of reorganization in the primary sensorimotor cortex. Mirror visual feedback therapy has been shown to improve phantom pain. We investigated the extent of cortical reorganization in lower limb amputees and changes in neural activity induced by mirror therapy. Eight lower limb amputees underwent 12 sessions of MVFT and functional magnetic resonance imaging (fMRI) of the brain before the first and after the last MVFT session. FMRI sessions consisted of two runs in which subjects were instructed to perform repetitive movement of the healthy and phantom ankle. Before MVFT, the mean phantom pain intensity was 4.6 ± 3.1 on a visual analog scale and decreased to 1.8 ± 1.7 (p = 0.04). We did not observe a consistent pattern of cortical activation in primary sensorimotor areas during phantom limb movements. Following MVFT, increased activity was obtained in the right orbitofrontal cortex during phantom ankle movements. Comparison of cortical activity during movements of the phantom ankle and the intact ankle showed significantly higher activity in the left inferior frontal cortex (pars triangularis). These results question the known association between phantom pain and primary sensorimotor reorganization and propose reorganizational changes involving multiple cortical areas in lower limb amputees. Finally, reduction of phantom pain after mirror visual feedback therapy was associated with increased prefrontal cortical activity during phantom ankle movements. (orig.)

Experimental evidence of dynamic re-organization of evolving landscapes under changing climatic forcing

Science.gov (United States)

Singh, Arvind; Tejedor, Alejandro; Zaliapin, Ilya; Reinhardt, Liam; Foufoula-Georgiou, Efi

2015-04-01

The aim of this study is to better understand the dynamic re-organization of an evolving landscape under a scenario of changing climatic forcing for improving our knowledge of geomorphic transport laws under transient conditions and developing predictive models of landscape response to external perturbations. Real landscape observations for long-term analysis are limited and to this end a high resolution controlled laboratory experiment was conducted at the St. Anthony Falls laboratory at the University of Minnesota. Elevation data were collected at temporal resolution of 5 mins and spatial resolution of 0.5 mm as the landscape approached steady state (constant uplift and precipitation rate) and in the transient state (under the same uplift and 5x precipitation). The results reveal rapid topographic re-organization under a five-fold precipitation increase with the fluvial regime expanding into the previously debris dominated regime, accelerated erosion happening at hillslope scales, and rivers shifting from an erosion-limited to a transport-limited regime. From a connectivity and clustering analysis of the erosional and depositional events, we demonstrate the strikingly different spatial patterns of landscape evolution under steady-state (SS) and transient-state (TS), even when the time under SS is "stretched" compared to that under TS such as to match the total volume and PDF of erosional and depositional amounts. We quantify the spatial coupling of hillslopes and channels and demonstrate that hillslopes lead and channels follow in re-organizing the whole landscape under such an amplified precipitation regime.

CD82 endocytosis and cholesterol-dependent reorganization of tetraspanin webs and lipid rafts

Science.gov (United States)

Xu, Congfeng; Zhang, Yanhui H.; Thangavel, Muthusamy; Richardson, Mekel M.; Liu, Li; Zhou, Bin; Zheng, Yi; Ostrom, Rennolds S.; Zhang, Xin A.

2009-01-01

Tetraspanin CD82 suppresses cell migration, tumor invasion, and tumor metastasis. To determine the mechanism by which CD82 inhibits motility, most studies have focused on the cell surface CD82, which forms tetraspanin-enriched microdomains (TEMs) with other transmembrane proteins, such as integrins. In this study, we found that CD82 undergoes endocytosis and traffics to endosomes and lysosomes. To determine the endocytic mechanism of CD82, we demonstrated that dynamin and clathrin are not essential for CD82 internalization. Depletion or sequestration of sterol in the plasma membrane markedly inhibited the endocytosis of CD82. Despite the demand on Cdc42 activity, CD82 endocytosis is distinct from macropinocytosis and the documented dynamin-independent pinocytosis. As a TEM component, CD82 reorganizes TEMs and lipid rafts by redistributing cholesterol into these membrane microdomains. CD82-containing TEMs are characterized by the cholesterol-containing microdomains in the extreme light- and intermediate-density fractions. Moreover, the endocytosis of CD82 appears to alleviate CD82-mediated inhibition of cell migration. Taken together, our studies demonstrate that lipid-dependent endocytosis drives CD82 trafficking to late endosomes and lysosomes, and CD82 reorganizes TEMs and lipid rafts through redistribution of cholesterol.—Xu, C., Zhang, Y. H., Thangavel, M., Richardson, M. M., Liu, L., Zhou, B., Zheng, Y., Ostrom, R. S., Zhang, X. A. CD82 endocytosis and cholesterol-dependent reorganization of tetraspanin webs and lipid rafts. PMID:19497983

Web 2.0 Impact on Business Value at a Federal Government Housing Agency

Science.gov (United States)

Lavender, Anthony L.

2013-01-01

The idea of Open Government is an extension of the Electronic Government Act of 2002 which addresses the accessibility, usability, and preservation of government information. The concept of Open Government has evolved into the open government directive that mandates Executive Departments and Agencies to become more open and transparent while…

26 CFR 1.358-6 - Stock basis in certain triangular reorganizations.

Science.gov (United States)

2010-04-01

... corporation on the exchange of property for the assets or stock of a target corporation in a reorganization... percentage of T stock not acquired in the transaction is determined by taking into account the fair market... aggregate basis of $60 and fair market value of $100 and no liabilities. Pursuant to a plan, P forms S with...

A gauge-invariant reorganization of thermal gauge theory

International Nuclear Information System (INIS)

Su, Nan

2010-01-01

This dissertation is devoted to the study of thermodynamics for quantum gauge theories. The poor convergence of quantum field theory at finite temperature has been the main obstacle in the practical applications of thermal QCD for decades. In this dissertation I apply hard-thermal-loop perturbation theory, which is a gauge-invariant reorganization of the conventional perturbative expansion for quantum gauge theories to the thermodynamics of QED and Yang-Mills theory to three-loop order. For the Abelian case, I present a calculation of the free energy of a hot gas of electrons and photons by expanding in a power series in m D /T, m f /T and e 2 , where m D and m f are the photon and electron thermal masses, respectively, and e is the coupling constant. I demonstrate that the hard-thermal-loop perturbation reorganization improves the convergence of the successive approximations to the QED free energy at large coupling, e ∝ 2. For the non-Abelian case, I present a calculation of the free energy of a hot gas of gluons by expanding in a power series in m D /T and g 2 , where m D is the gluon thermal mass and g is the coupling constant. I show that at three-loop order hard-thermal-loop perturbation theory is compatible with lattice results for the pressure, energy density, and entropy down to temperatures T ∝ 2 - 3 T c . The results suggest that HTLpt provides a systematic framework that can be used to calculate static and dynamic quantities for temperatures relevant at LHC. (orig.)

[The political project and governance capacities].

Science.gov (United States)

Spinelli, Hugo

2012-01-01

This article presents a theoretical overview of personal and institutional governance capacities (experience, leadership and knowledge on the individual level, and organizational capital available on the institutional level) and their relationship to politics and policies in the Latin American context. Using the theoretical production of Carlos Matus regarding the act of governing, diverse dimensions of this problem are put into discussion in relation to other authors and experiences in different historical moments. Theories, methods and techniques of government are explored and the need for state reform with an internal logic is analyzed. It is concluded that there is a need to build a theory for the practice of governing/managing public organizations, and this construction requires creative actions that use theory as a toolbox.

Product market competition and corporate governance

Directory of Open Access Journals (Sweden)

Julia Chou

2011-04-01

Full Text Available This paper investigates whether product market competition acts as an external mechanism for disciplining management and also whether there is any relationship between the degree of competition a firm faces and its corporate governance. We find that firms in competitive industries or with low market power tend to have weak corporate governance structures. Results are robust to various competition measures at firm and industry levels, even after controlling for firm-specific variables. We further find that corporate governance quality has a significant effect on performance only when product market competition is weak. The overall evidence suggests that product market competition has a substantial impact on corporate governance and that it substitutes for corporate governance quality. Finally, we provide evidence that the disciplinary force of competition on management is from the fear of liquidation.

The Factors and Transversal Reorganizations Principles of Romanian Textile Industry Enterprises using Activity-Based Costing Method

Directory of Open Access Journals (Sweden)

Sorinel Capusneanu

2007-04-01

Full Text Available This article describes the factors and the principles of transversal reorganization of the enterprises from the Romanian textile industry by adapting the Activity-Based Costing method (ABC to its specific. There are presented and analyzed the real possibilities of reorganization of the enterprises in Romania by elaboration of methodological phases that will be covered until the implementation of their transversal organization. Are we ready to adapt the Activity-Based Costing method to the specific of the Romanian textile industry and not only? Here is the question whose response we will find in this article.

Inter-hemispheric language functional reorganization in low-grade glioma patients after tumour surgery

NARCIS (Netherlands)

Kristo, Gert; Raemaekers, Mathijs; Rutten, Geert-Jan; de Gelder, Beatrice; Ramsey, Nick F.

Despite many claims of functional reorganization following tumour surgery, empirical studies that investigate changes in functional activation patterns are rare. This study investigates whether functional recovery following surgical treatment in patients with a low-grade glioma in the left

Inter-hemispheric language functional reorganization in low-grade glioma patients after tumour surgery

NARCIS (Netherlands)

Kristo, Gert; Raemaekers, Mathijs; Rutten, Geert Jan; de Gelder, Beatrice; Ramsey, Nick F.

2015-01-01

Despite many claims of functional reorganization following tumour surgery, empirical studies that investigate changes in functional activation patterns are rare. This study investigates whether functional recovery following surgical treatment in patients with a low-grade glioma in the left

Importance of the Reorganization Energy Barrier in Computational Design of Porphyrin-Based Solar Cells with Cobalt-Based Redox Mediators

DEFF Research Database (Denmark)

Ørnsø, Kristian Baruël; Jónsson, Elvar Örn; Jacobsen, Karsten Wedel

2015-01-01

, and this limits the achievable efficiency. Here we show that the large driving force is a direct consequence of the large reorganization energy of the dye regeneration reaction. The reorganization energies for charge transfer between a simple zinc porphyrin dye and two popular cobalt-based redox mediators......The shift from iodide-based redox mediators in dye-sensitized solar cells toward octahedral cobalt complexes has led to a significant increase in the efficiency. However, due to the nature of this type of complexes the driving force required for the regeneration of the dye is very high...... to identify already known highperformance dyes in addition to a number of even better candidates. Our analysis shows that the large internal reorganization energy of the Co-based redox mediators is an obstacle for achieving higher efficiencies....

25 CFR 1000.162 - What is included in a self-governance compact?

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false What is included in a self-governance compact? 1000.162...-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiating A Self-Governance Compact § 1000.162 What is included in a self-governance compact? A model format for self-governance...

TANZANIA'S 2002 RECORDS AND ARCHIVES MANAGEMENT ACT

African Journals Online (AJOL)

However, some critical areas that need serious revisiting include supporting the Act with adequate resources, training, provisions on electronic records and records created by Union Government. The paper recommends facilitation of ample resources, training on the Act, reduction of power of director of the Records and ...

Do Kids Need Government Censors?

Science.gov (United States)

Rabkin, Rhoda

2002-01-01

Fashioning public policies restricting children's access to entertainment glamorizing violence, sex, drugs, and vulgarity is a complex task. The recently introduced Media Marketing Accountability Act would empower the federal government to regulate advertising of entertainment products to youth. Suggests that this power is undesirable compared to…

Sleep EEG Changes during Adolescence: An Index of a Fundamental Brain Reorganization

Science.gov (United States)

Feinberg, Irwin; Campbell, Ian G.

2010-01-01

Delta (1-4 Hz) EEG power in non-rapid eye movement (NREM) sleep declines massively during adolescence. This observation stimulated the hypothesis that during adolescence the human brain undergoes an extensive reorganization driven by synaptic elimination. The parallel declines in synaptic density, delta wave amplitude and cortical metabolic rate…

Dynamic neural network reorganization associated with second language vocabulary acquisition: a multimodal imaging study.

Science.gov (United States)

Hosoda, Chihiro; Tanaka, Kanji; Nariai, Tadashi; Honda, Manabu; Hanakawa, Takashi

2013-08-21

It remains unsettled whether human language relies exclusively on innately privileged brain structure in the left hemisphere or is more flexibly shaped through experiences, which induce neuroplastic changes in potentially relevant neural circuits. Here we show that learning of second language (L2) vocabulary and its cessation can induce bidirectional changes in the mirror-reverse of the traditional language areas. A cross-sectional study identified that gray matter volume in the inferior frontal gyrus pars opercularis (IFGop) and connectivity of the IFGop with the caudate nucleus and the superior temporal gyrus/supramarginal (STG/SMG), predominantly in the right hemisphere, were positively correlated with L2 vocabulary competence. We then implemented a cohort study involving 16 weeks of L2 training in university students. Brain structure before training did not predict the later gain in L2 ability. However, training intervention did increase IFGop volume and reorganization of white matter including the IFGop-caudate and IFGop-STG/SMG pathways in the right hemisphere. These "positive" plastic changes were correlated with the gain in L2 ability in the trained group but were not observed in the control group. We propose that the right hemispheric network can be reorganized into language-related areas through use-dependent plasticity in young adults, reflecting a repertoire of flexible reorganization of the neural substrates responding to linguistic experiences.

Support vector machine classification and characterization of age-related reorganization of functional brain networks.

Science.gov (United States)

Meier, Timothy B; Desphande, Alok S; Vergun, Svyatoslav; Nair, Veena A; Song, Jie; Biswal, Bharat B; Meyerand, Mary E; Birn, Rasmus M; Prabhakaran, Vivek

2012-03-01

Most of what is known about the reorganization of functional brain networks that accompanies normal aging is based on neuroimaging studies in which participants perform specific tasks. In these studies, reorganization is defined by the differences in task activation between young and old adults. However, task activation differences could be the result of differences in task performance, strategy, or motivation, and not necessarily reflect reorganization. Resting-state fMRI provides a method of investigating functional brain networks without such confounds. Here, a support vector machine (SVM) classifier was used in an attempt to differentiate older adults from younger adults based on their resting-state functional connectivity. In addition, the information used by the SVM was investigated to see what functional connections best differentiated younger adult brains from older adult brains. Three separate resting-state scans from 26 younger adults (18-35 yrs) and 26 older adults (55-85) were obtained from the International Consortium for Brain Mapping (ICBM) dataset made publically available in the 1000 Functional Connectomes project www.nitrc.org/projects/fcon_1000. 100 seed-regions from four functional networks with 5mm(3) radius were defined based on a recent study using machine learning classifiers on adolescent brains. Time-series for every seed-region were averaged and three matrices of z-transformed correlation coefficients were created for each subject corresponding to each individual's three resting-state scans. SVM was then applied using leave-one-out cross-validation. The SVM classifier was 84% accurate in classifying older and younger adult brains. The majority of the connections used by the classifier to distinguish subjects by age came from seed-regions belonging to the sensorimotor and cingulo-opercular networks. These results suggest that age-related decreases in positive correlations within the cingulo-opercular and default networks, and decreases in

Homotopic Language Reorganization in the Right Hemisphere after Early Left Hemisphere Injury

Science.gov (United States)

Tivarus, Madalina E.; Starling, Sarah J.; Newport, Elissa L.; Langfitt, John T.

2012-01-01

To determine the areas involved in reorganization of language to the right hemisphere after early left hemisphere injury, we compared fMRI activation patterns during four production and comprehension tasks in post-surgical epilepsy patients with either left (LH) or right hemisphere (RH) speech dominance (determined by Wada testing) and healthy…

Atomic Energy Authority Act 1986

International Nuclear Information System (INIS)

1986-01-01

Under this Act the UKAEA is given power to borrow so that it can finance its capital expenditure programme, and will undertake a debt to the Secretary of State for Energy representing its assets. Power is given for the Government to guarantee such borrowing. The UKAEA has been organised financially on the basis of a trading fund. The Act came into force on 1 April 1986. (NEA) [fr

Modernizing the Federal Government: Paying for Performance

Science.gov (United States)

2007-01-01

works (Barr, 2007d). Employees are rated on performance measures such as “fair and equitable treatment of taxpayers” and “customer satisfaction ... Performance Act of 2007, Senate bill 1046, Washington, D.C., 2007b. 38 Modernizing the Federal Government: Paying for Performance Vroom , Victor H...AND SUBTITLE Modernizing the federal government paying for performance 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR

13 CFR 107.470 - SBA approval of merger, consolidation, or reorganization of Licensee.

Science.gov (United States)

2010-01-01

... BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Changes in Ownership, Control, or Structure of Licensee; Transfer of License Change in Structure of Licensee § 107.470 SBA approval of merger..., change form of organization (corporation or partnership) or reorganize without SBA's prior written...

A BCM theory of meta-plasticity for online self-reorganizing fuzzy-associative learning.

Science.gov (United States)

Tan, Javan; Quek, Chai

2010-06-01

Self-organizing neurofuzzy approaches have matured in their online learning of fuzzy-associative structures under time-invariant conditions. To maximize their operative value for online reasoning, these self-sustaining mechanisms must also be able to reorganize fuzzy-associative knowledge in real-time dynamic environments. Hence, it is critical to recognize that they would require self-reorganizational skills to rebuild fluid associative structures when their existing organizations fail to respond well to changing circumstances. In this light, while Hebbian theory (Hebb, 1949) is the basic computational framework for associative learning, it is less attractive for time-variant online learning because it suffers from stability limitations that impedes unlearning. Instead, this paper adopts the Bienenstock-Cooper-Munro (BCM) theory of neurological learning via meta-plasticity principles (Bienenstock et al., 1982) that provides for both online associative and dissociative learning. For almost three decades, BCM theory has been shown to effectively brace physiological evidence of synaptic potentiation (association) and depression (dissociation) into a sound mathematical framework for computational learning. This paper proposes an interpretation of the BCM theory of meta-plasticity for an online self-reorganizing fuzzy-associative learning system to realize online-reasoning capabilities. Experimental findings are twofold: 1) the analysis using S&P-500 stock index illustrated that the self-reorganizing approach could follow the trajectory shifts in the time-variant S&P-500 index for about 60 years, and 2) the benchmark profiles showed that the fuzzy-associative approach yielded comparable results with other fuzzy-precision models with similar online objectives.

Magnuson-Stevens Fishery Conservation Act

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Magnuson-Stevens Fishery Conservation and Management Act (MSA) is the primary law governing marine fisheries management in U.S. federal waters. It has since been...

Financial accountability: the principal or the school governing body ...

African Journals Online (AJOL)

The Schools Act 84 of 1996 prescribes how a school should manage its funds. It also provides guidelines for the school governing body and the principal on their roles and responsibilities in managing the finances of the school. However, there are school governing bodies and principals that have little knowledge of the ...

A gauge-invariant reorganization of thermal gauge theory

Energy Technology Data Exchange (ETDEWEB)

Su, Nan

2010-07-01

This dissertation is devoted to the study of thermodynamics for quantum gauge theories. The poor convergence of quantum field theory at finite temperature has been the main obstacle in the practical applications of thermal QCD for decades. In this dissertation I apply hard-thermal-loop perturbation theory, which is a gauge-invariant reorganization of the conventional perturbative expansion for quantum gauge theories to the thermodynamics of QED and Yang-Mills theory to three-loop order. For the Abelian case, I present a calculation of the free energy of a hot gas of electrons and photons by expanding in a power series in m{sub D}/T, m{sub f}/T and e{sup 2}, where m{sub D} and m{sub f} are the photon and electron thermal masses, respectively, and e is the coupling constant. I demonstrate that the hard-thermal-loop perturbation reorganization improves the convergence of the successive approximations to the QED free energy at large coupling, e {proportional_to} 2. For the non-Abelian case, I present a calculation of the free energy of a hot gas of gluons by expanding in a power series in m{sub D}/T and g{sup 2}, where m{sub D} is the gluon thermal mass and g is the coupling constant. I show that at three-loop order hard-thermal-loop perturbation theory is compatible with lattice results for the pressure, energy density, and entropy down to temperatures T {proportional_to} 2 - 3 T{sub c}. The results suggest that HTLpt provides a systematic framework that can be used to calculate static and dynamic quantities for temperatures relevant at LHC. (orig.)

43 CFR 12.830 - Buy American Act-Construction materials.

Science.gov (United States)

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Buy American Act-Construction materials... Assistance Programs Buy American Act-Construction Materials § 12.830 Buy American Act—Construction materials...—Construction Materials (a) The Buy American Act (41 U.S.C. 10) provides that the Government give preference to...

Reorganization of finger coordination patterns through motor exploration in individuals after stroke.

Science.gov (United States)

Ranganathan, Rajiv

2017-09-11

Impairment of hand and finger function after stroke is common and affects the ability to perform activities of daily living. Even though many of these coordination deficits such as finger individuation have been well characterized, it is critical to understand how stroke survivors learn to explore and reorganize their finger coordination patterns for optimizing rehabilitation. In this study, I examine the use of a body-machine interface to assess how participants explore their movement repertoire, and how this changes with continued practice. Ten participants with chronic stroke wore a data glove and the finger joint angles were mapped on to the position of a cursor on a screen. The task of the participants was to move the cursor back and forth between two specified targets on a screen. Critically, the map between the finger movements and cursor motion was altered so that participants sometimes had to generate coordination patterns that required finger individuation. There were two phases to the experiment - an initial assessment phase on day 1, followed by a learning phase (days 2-5) where participants trained to reorganize their coordination patterns. Participants showed difficulty in performing tasks which had maps that required finger individuation, and the degree to which they explored their movement repertoire was directly related to clinical tests of hand function. However, over four sessions of practice, participants were able to learn to reorganize their finger movement coordination pattern and improve their performance. Moreover, training also resulted in improvements in movement repertoire outside of the context of the specific task during free exploration. Stroke survivors show deficits in movement repertoire in their paretic hand, but facilitating movement exploration during training can increase the movement repertoire. This suggests that exploration may be an important element of rehabilitation to regain optimal function.

Identifying functional reorganization of spelling networks: an individual peak probability comparison approach

Science.gov (United States)

Purcell, Jeremy J.; Rapp, Brenda

2013-01-01

Previous research has shown that damage to the neural substrates of orthographic processing can lead to functional reorganization during reading (Tsapkini et al., 2011); in this research we ask if the same is true for spelling. To examine the functional reorganization of spelling networks we present a novel three-stage Individual Peak Probability Comparison (IPPC) analysis approach for comparing the activation patterns obtained during fMRI of spelling in a single brain-damaged individual with dysgraphia to those obtained in a set of non-impaired control participants. The first analysis stage characterizes the convergence in activations across non-impaired control participants by applying a technique typically used for characterizing activations across studies: Activation Likelihood Estimate (ALE) (Turkeltaub et al., 2002). This method was used to identify locations that have a high likelihood of yielding activation peaks in the non-impaired participants. The second stage provides a characterization of the degree to which the brain-damaged individual's activations correspond to the group pattern identified in Stage 1. This involves performing a Mahalanobis distance statistics analysis (Tsapkini et al., 2011) that compares each of a control group's peak activation locations to the nearest peak generated by the brain-damaged individual. The third stage evaluates the extent to which the brain-damaged individual's peaks are atypical relative to the range of individual variation among the control participants. This IPPC analysis allows for a quantifiable, statistically sound method for comparing an individual's activation pattern to the patterns observed in a control group and, thus, provides a valuable tool for identifying functional reorganization in a brain-damaged individual with impaired spelling. Furthermore, this approach can be applied more generally to compare any individual's activation pattern with that of a set of other individuals. PMID:24399981

Reorganization of the human central nervous system.

Science.gov (United States)

Schalow, G; Zäch, G A

2000-10-01

The key strategies on which the discovery of the functional organization of the central nervous system (CNS) under physiologic and pathophysiologic conditions have been based included (1) our measurements of phase and frequency coordination between the firings of alpha- and gamma-motoneurons and secondary muscle spindle afferents in the human spinal cord, (2) knowledge on CNS reorganization derived upon the improvement of the functions of the lesioned CNS in our patients in the short-term memory and the long-term memory (reorganization), and (3) the dynamic pattern approach for re-learning rhythmic coordinated behavior. The theory of self-organization and pattern formation in nonequilibrium systems is explicitly related to our measurements of the natural firing patterns of sets of identified single neurons in the human spinal premotor network and re-learned coordinated movements following spinal cord and brain lesions. Therapy induced cell proliferation, and maybe, neurogenesis seem to contribute to the host of structural changes during the process of re-learning of the lesioned CNS. So far, coordinated functions like movements could substantially be improved in every of the more than 100 patients with a CNS lesion by applying coordination dynamic therapy. As suggested by the data of our patients on re-learning, the human CNS seems to have a second integrative strategy for learning, re-learning, storing and recalling, which makes an essential contribution of the functional plasticity following a CNS lesion. A method has been developed by us for the simultaneous recording with wire electrodes of extracellular action potentials from single human afferent and efferent nerve fibres of undamaged sacral nerve roots. A classification scheme of the nerve fibres in the human peripheral nervous system (PNS) could be set up in which the individual classes of nerve fibres are characterized by group conduction velocities and group nerve fibre diameters. Natural impulse patterns

The reorganization of the nuclear sector in France

International Nuclear Information System (INIS)

2001-05-01

In November 2000, the French ministry of economy, finances and industry presented a project of reorganization of the overall French nuclear sector which aims at grouping together the activities of CEA-Industrie, Cogema and Framatome in a single huge industrial group. This group will comprise two main poles, a purely nuclear one around Cogema and Framatome, and a pole devoted to new technologies with the connector activities of Framatome and the shares of CEA-Industrie in STMicroelectronics. This new group should make a funded turnover of 10 billions of euros with a net result (share of the group) of 500 millions of euros. It will employ 45000 people. (J.S.)

Problems concerning the Federal Government-Laender relationship in nuclear law

International Nuclear Information System (INIS)

Lange, K.

1990-01-01

The Atomic Energy Act is characterized by extremely extensive powers of decision and sole responsibility of the executive. Its profile is determined by discretionary assessment powers in connection with the interpretation of the given preconditions of pertinent legal standards and by judically not verifiable assessment possibilities in connection with legal consequences. In this situation, the authority to instruct, given to the Federal Government within the framework of the execution of Federal laws by Laender according to the instructions of the Federal Government pursuant to section 85 III Basic Law, is of special, far-reaching significance. The article investigates the limitatations of the Federal Government's power to instruct Laender to carry out activities underlying Federal laws: The burden has to be bearable for the Laender, the directions have to be absolutely clear. The fruitlessness of a Federal Government-Laender court case, in which a Land turns to the Federal Constitutional Court because of an instruction which, in the Land's eyes, would lead it to act unlawfully, does not principally exclude a Land from seeking legal protection in the administrative courts of law. It can only be hoped that the Federal Government will make use of its powers to instruct Laender with the necessary sensitivity, also in those cases when Laender, according to an appropriate decision of the Federal Constitutional Court, cannot enforce by legal proceedings the state's obligation to act in line with legal order. (orig./HSCH) [de

Choice between hierarchy and market: Case of Central Electricity Generating Board's reorganization

International Nuclear Information System (INIS)

Caroli, M.

1992-01-01

Through the use of the 'Organization and Market' theoretical approach, this article outlines CEGB's reorganization to evaluate this experience under the strategic planning and operating effectiveness perspectives. The first part synthesizes the basic points of the 1990 reform which divided CEGB into three different companies and separated the control of the generation of electric power from its transport. The second part summarizes the main considerations about conditions of efficiency of vertical integration and disintegration, according to the 'Organization and Market' approach. By utilizing the conclusions highlighted in the first two parts of this article, the third one studies the effects of CEGB's vertical disintegration on the level of competition in power generation market; on CEGB's strategic effectiveness and operative efficiency; and on transactional costs in the electric power industry. CEGB's reorganization does not seem to have had a relevantly positive effect on competition, while it has caused a strategic burden and a significant increase of transactional costs in the exchange of electricity between the generator and the transmitter

Convergence of Corporate and Public Governance

Directory of Open Access Journals (Sweden)

Gérard Hirigoyen

2013-06-01

Full Text Available By analyzing the differences between the corporate and public governance, theoretical and empirical research seems to indicate that the two domains of governance are far too different to share any common aspect. However, in this particular research, it has been argued that public governance is an application of corporate governance. Thus, the research question entails the description and analysis of this possible convergence of the two. Extensive research from literature on corporate governance has been undertaken to establish a relationship between the boards process and the roles that acts as a framework to bridge the gap separating corporate governance from public governance. Corporate governance, at a global level, exists in the for-profit as well as nonprofit organizations. Thus, the definition of this concept needs to be viewed from “an innovative” eye, considering the relationship between the process of the board and roles as characteristic of the public organization and private ones. As the private as well as public organizations are an application of corporate governance, the difference between the two gets narrowed. For the purpose of this research, the case of the French hospitals’ board has been taken into consideration. The members of the public board have been considered for the board process to perform their roles.

E-Government and Corruption in Mexico (2005-2010

Directory of Open Access Journals (Sweden)

Delia Laura Sour Vargas

2017-10-01

Full Text Available Several studies prove that e-government is a tool that facilitates transactions and the exchange of information digitally between the public administration and citizens, minimizing the probability of corrupt acts. However, this issue has been little studied for the case of Mexico. This paper analyzes the impact of the dissemination of information and transactions through e-government on the National Corruption and Good Governance Index for 2005-2010 at the State and the Federal District levels. Results indicate that the impact of e-government has been significant, but modest. These data enrich the discussion on the changes required to alleviate the problem of corruption in the country.

The origin of Mauna Loa's Nīnole Hills: Evidence of rift zone reorganization

Science.gov (United States)

Zurek, Jeffrey; Williams-Jones, Glyn; Trusdell, Frank A.; Martin, Simon

2015-01-01

In order to identify the origin of Mauna Loa volcano's Nīnole Hills, Bouguer gravity was used to delineate density contrasts within the edifice. Our survey identified two residual anomalies beneath the Southwest Rift Zone (SWRZ) and the Nīnole Hills. The Nīnole Hills anomaly is elongated, striking northeast, and in inversions both anomalies merge at approximately −7 km above sea level. The positive anomaly, modeled as a rock volume of ~1200 km3 beneath the Nīnole Hills, is associated with old eruptive vents. Based on the geologic and geophysical data, we propose that the gravity anomaly under the Nīnole Hills records an early SWRZ orientation, now abandoned due to geologically rapid rift-zone reorganization. Catastrophic submarine landslides from Mauna Loa's western flank are the most likely cause for the concurrent abandonment of the Nīnole Hills section of the SWRZ. Rift zone reorganization induced by mass wasting is likely more common than currently recognized.

A Flight Plan for the Community Media Act

Directory of Open Access Journals (Sweden)

Jesús Enrique Urbina Serjant

2012-02-01

Full Text Available In the design and implementation of public policy, planning usually plays a unique role. Government interventions generally follow a pattern conceived with forethought. In the case of President Hugo Chavez’ Administration (1999 to present, little has been left to chance in the most important impact on the communications sector: the legal regulation, control of broadcasters, the consolidation of public media and sponsorship of community media. As he has been radicalizing his Bolivarian political project, Chávez weaves forecasts consistent communication policy in the content of government plans. The draft Community Media Act is a good example of synchronicity between government actions and communications sector address of the "revolution". The popular initiative for submission of the Act was not spontaneous or its rules respond to genuine community interest.

Recent Developments in German Corporate Governance

NARCIS (Netherlands)

Goergen, M.; Manjon, M.C.; Renneboog, L.D.R.

2004-01-01

We contrast the features of the German corporate governance system with those of other systems and discuss the recent regulatory initiatives.For example, the rules on insider trading and anti-trust have been strengthened.The Restructuring Act has been revised to prevent minority shareholders from

Local government under the defenders of the constitution

Directory of Open Access Journals (Sweden)

Svirčević Miroslav

2004-01-01

Full Text Available The paper explains the development of local government under the rule of the constitution defenders 1842-1858. The author describes the historical facts that led to the abdication of Prince Miloš and the establishment of an oligarchic government of chieftains assembled in a council (Toma Vučić Perišić, Avram Petronijević, Hadji Milutin Garašanin and his son Ilija Stojan and Aleksa Simić, as well as the process of building a modern state administration and cultural identity, an integral part of which was a narrower process of constituting local government. A distinct role in the latter process was played by the Austrian-born Serbs, the only intelligentsia in the Principality of Serbia which was still under Turkish suzerainty. Special attention is given to the analysis of two local government acts instituting centralized local authorities with an enhanced law enforcement role in the districts, counties and communes. Those are District Prefectural System and of County Prefect Office Act of 12 May 1839 and Communal System Act of 13 July the same year. Of great importance was the former law, one of the longest-lived in the history of nineteenth-century Serbian constitutionalism. It was in force in 1839-88 and 1894-1903. Every autocratic regime in Serbia was to rely on it. Its distinctive feature is that it subordinated district and county prefects to the central authority and to the minister of internal affairs. They were reduced to mere police agents deprived of any freedom of action. Thus the local officials assumed the character of rigid administrators looking down on the common people. A natural continuation of this law was the other law of communal organization which turned the lowest local units into mere executive agencies of counties. Thus local government took on the form of a mere transmission of the central government, functioning according to a principle similar to the medieval lord-vassal system: my vassal's vassal is not my

Impacts of imports, government policy and technology on future natural gas supply

International Nuclear Information System (INIS)

Allison, E.

2009-01-01

This presentation discussed the impacts of imports, government policy and technology on future natural gas supply. Specifically, it discussed projections of natural gas supply and demand; the potential impact of imports on United States natural gas supply; the potential impacts of government policy on natural gas supply and demand; and the impact of technological innovations on natural gas supply such as coalbed methane and methane hydrate. Specific government policies that were examined included the American Recovery and Reinvestment Act of 2009; the American Clean Energy and Security Act of 2009; and the Clean Energy Jobs and American Power Act of 2009. It was concluded that the United States demand for natural gas will expand and that the impact of pending clean energy legislation is unclear. In addition, each potential future resource will face constraints and new resources may come on line in the next 20 years. figs.

Lipid reorganization induced by Shiga toxin clustering on planar membranes.

Directory of Open Access Journals (Sweden)

Barbara Windschiegl

Full Text Available The homopentameric B-subunit of bacterial protein Shiga toxin (STxB binds to the glycolipid Gb(3 in plasma membranes, which is the initial step for entering cells by a clathrin-independent mechanism. It has been suggested that protein clustering and lipid reorganization determine toxin uptake into cells. Here, we elucidated the molecular requirements for STxB induced Gb(3 clustering and for the proposed lipid reorganization in planar membranes. The influence of binding site III of the B-subunit as well as the Gb(3 lipid structure was investigated by means of high resolution methods such as fluorescence and scanning force microscopy. STxB was found to form protein clusters on homogenous 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC/cholesterol/Gb(3 (65:30:5 bilayers. In contrast, membranes composed of DOPC/cholesterol/sphingomyelin/Gb(3 (40:35:20:5 phase separate into a liquid ordered and liquid disordered phase. Dependent on the fatty acid composition of Gb(3, STxB-Gb(3 complexes organize within the liquid ordered phase upon protein binding. Our findings suggest that STxB is capable of forming a new membrane phase that is characterized by lipid compaction. The significance of this finding is discussed in the context of Shiga toxin-induced formation of endocytic membrane invaginations.

Melting temperature evolution of non-reorganized crystals. Poly(3-hydroxybutyrate)

International Nuclear Information System (INIS)

Righetti, Maria Cristina; Di Lorenzo, Maria Laura

2011-01-01

In the present study the correlation between the melting behaviour of poly(3-hydroxybutyrate) (PHB) original, non-reorganized crystals and the crystallinity increase during isothermal crystallization is presented and discussed. Since the reorganization processes modify the melting curve of original crystals, it is necessary to prevent and hinder all the processes that influence and increase the lamellar thickness. PHB exhibits melting/recrystallization on heating, the occurring of lamellar thickening in the solid state being excluded. The first step of the study was the identification of the scanning rate which inhibits PHB recrystallization at sufficiently high T c . For the extrapolated onset and peak temperatures of the main melting endotherm, which is connected to fusion of dominant lamellae, a double dependence on the crystallization time was found. The crystallization time at which T onset and T peak change their trends was found to correspond to the spherulite impingement time, so that the two different dependencies were put in relation with primary and secondary crystallizations respectively. The increase of both T onset and T peak at high crystallization times after spherulite impingement was considered an effect due to crystal superheating and an indication of a stabilization process of the crystalline phase. Such stabilization, which produces an increase of the melting temperature, is probably connected with the volume filling that occurs after spherulite impingement.

75 FR 48996 - National Science Board; Sunshine Act Meetings; Notice

Science.gov (United States)

2010-08-12

... NATIONAL SCIENCE FOUNDATION National Science Board; Sunshine Act Meetings; Notice The National Science Board's Committee on Audit & Oversight, pursuant to NSF regulations (45 CFR part 614), the National Science Foundation Act, as amended (42 U.S.C. 1862n-5), and the Government in the Sunshine Act (5...

26 CFR 1.368-1 - Purpose and scope of exception of reorganization exchanges.

Science.gov (United States)

2010-04-01

... target corporation's (T's) historic business or use a significant portion of T's historic business assets.... However, all other facts and circumstances, such as the net fair market value of those assets, will be... interests in the target corporation be preserved in the reorganization. A proprietary interest in the target...

Detection of Brain Reorganization in Pediatric Multiple Sclerosis Using Functional MRI

Science.gov (United States)

2015-10-01

including the Wechsler Intelligence Scale for Children (WISC-IV) for verbal and non-verbal intelligence; the Boston Naming Test , which evaluates a...demonstrated congruency between fMRI mappings and patient performance; 2) testing of the fMRI methods we developed for use in POMS patients was carried out...adaptive functional reorganization as a way to explain how some early-stage MS patients are able to perform well in clinical cognitive testing

78 FR 2961 - Sunshine Act Meeting-Closed Meeting

Science.gov (United States)

2013-01-15

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meeting--Closed Meeting The following notice of a closed meeting is published pursuant to the provisions of the Government in the Sunshine Act, Public Law 94- 409, 5 U.S.C. 552b. AGENCY HOLDING THE MEETING: Commodity Futures Trading Commission. TIME...

78 FR 6306 - Sunshine Act Meeting-Closed Meeting

Science.gov (United States)

2013-01-30

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meeting--Closed Meeting The following notice of a closed meeting is published pursuant to the provisions of the Government in the Sunshine Act, Public Law 94- 409, 5 U.S.C. 552b. AGENCY HOLDING THE MEETING: Commodity Futures Trading Commission. TIME...

Governance challenges in Tanzania's environmental impact ...

African Journals Online (AJOL)

The article argues that, inadequate or lack of accountability in enforcing the Environmental Management Act is a governance failure, that renders the EIA process ineffective. The article calls for a re-assessment of the theoretical arguments used to understand effectiveness to include sociological and psychological factors, ...

Large-Scale Functional Brain Network Reorganization During Taoist Meditation.

Science.gov (United States)

Jao, Tun; Li, Chia-Wei; Vértes, Petra E; Wu, Changwei Wesley; Achard, Sophie; Hsieh, Chao-Hsien; Liou, Chien-Hui; Chen, Jyh-Horng; Bullmore, Edward T

2016-02-01

Meditation induces a distinct and reversible mental state that provides insights into brain correlates of consciousness. We explored brain network changes related to meditation by graph theoretical analysis of resting-state functional magnetic resonance imaging data. Eighteen Taoist meditators with varying levels of expertise were scanned using a within-subjects counterbalanced design during resting and meditation states. State-related differences in network topology were measured globally and at the level of individual nodes and edges. Although measures of global network topology, such as small-worldness, were unchanged, meditation was characterized by an extensive and expertise-dependent reorganization of the hubs (highly connected nodes) and edges (functional connections). Areas of sensory cortex, especially the bilateral primary visual and auditory cortices, and the bilateral temporopolar areas, which had the highest degree (or connectivity) during the resting state, showed the biggest decrease during meditation. Conversely, bilateral thalamus and components of the default mode network, mainly the bilateral precuneus and posterior cingulate cortex, had low degree in the resting state but increased degree during meditation. Additionally, these changes in nodal degree were accompanied by reorganization of anatomical orientation of the edges. During meditation, long-distance longitudinal (antero-posterior) edges increased proportionally, whereas orthogonal long-distance transverse (right-left) edges connecting bilaterally homologous cortices decreased. Our findings suggest that transient changes in consciousness associated with meditation introduce convergent changes in the topological and spatial properties of brain functional networks, and the anatomical pattern of integration might be as important as the global level of integration when considering the network basis for human consciousness.

Achieving quality in a government hospital: departmental responsibility.

Science.gov (United States)

Haron, Yafa; Segal, Zvi; Barhoum, Masad

2009-01-01

Quality improvement in health care organizations requires structural reorganization and system reform and the development of an appropriate organizational "culture." In 2007, the Division of Quality and Excellence in Civil Service in Israel developed a concept to improve quality management in governmental institutions throughout the country. To put this strategy into practice, Western Galilee Hospital, a governmental hospital, in northern Israel, developed a plan to advance the quality management system where each department and unit is autonomously responsible for its own quality and excellence. Since the hospital has been certificated by ISO 9001 for more than 10 years (the only hospital in Israel to have this certificate), the main challenge now is to improve the quality and excellence system in every department. The aim of this article is to describe the implementation of a comprehensive program designed to raise the ability of managers and workers in Western Galilee Hospital in addressing all of the government's requirements for quality and excellence in service in Israel.

Language localization in cases of left temporal lobe arachnoid cyst : Evidence against interhemispheric reorganization

NARCIS (Netherlands)

Stowe, LA; Go, KG; Pruim, J; den Dunnen, W; Meiners, LC; Paans, AMJ

2000-01-01

We investigated whether left-hemisphere arachnoid cysts lead to reorganization of the language function using PET. A group analysis demonstrated that patients showed no more right-hemisphere activation than a matched control group. Several patients had clear language localizations in the left

Changes of Global Infectious Disease Governance in 2000s: Rise of Global Health Security and Transformation of Infectious Disease Control System in South Korea

Directory of Open Access Journals (Sweden)

Eun Kyung CHOI

2016-12-01

Full Text Available This paper focus upon the changes of global infectious disease governance in 2000s and the transformation of infectious disease control system in South Korea. Traditionally, infectious disease was globally governed by the quarantine regulated by the international conventions. When an infectious disease outbreak occurred in one country, each country prevented transmission of the disease through the standardized quarantine since the installation of international sanitary convention in 1892. Republic of Korea also organized the infectious disease control system with quarantine and disease report procedure after the establishment of government. Additionally, Korea National Health Institute(KNIH was founded as research and training institute for infectious disease. However, traditional international health regulation system faced a serious challenge by the appearance of emerging and re-emerging infectious disease in 1990s. As a result, global infectious disease governance was rapidly changed under the demand to global disease surveillance and response. Moreover, global health security frame became important after 2001 bioterror and 2003 SARS outbreak. Consequently, international health regulation was fully revised in 2005, which included not only infectious disease but also public health emergency. The new international health regime was differently characterized in several aspects; reinforcement of global cooperation and surveillance, enlargement of the role of supranational and international agencies, and reorganization of national capacity. KNIH was reorganized with epidemic control and research since late 1990s. However, in 2004 Korea Center for Disease Control and Prevention(KCDC was established as a disease control institution with combining quarantine and other functions after 2003 SARS outbreak. KCDC unified national function against infectious disease including prevention, protection, response and research, as a national representative in

Changes of Global Infectious Disease Governance in 2000s: Rise of Global Health Security and Transformation of Infectious Disease Control System in South Korea.

Science.gov (United States)

Choi, Eun Kyung; Lee, Jong-Koo

2016-12-01

This paper focus upon the changes of global infectious disease governance in 2000s and the transformation of infectious disease control system in South Korea. Traditionally, infectious disease was globally governed by the quarantine regulated by the international conventions. When an infectious disease outbreak occurred in one country, each country prevented transmission of the disease through the standardized quarantine since the installation of international sanitary convention in 1892. Republic of Korea also organized the infectious disease control system with quarantine and disease report procedure after the establishment of government. Additionally, Korea National Health Institute(KNIH) was founded as research and training institute for infectious disease. However, traditional international health regulation system faced a serious challenge by the appearance of emerging and re-emerging infectious disease in 1990s. As a result, global infectious disease governance was rapidly changed under the demand to global disease surveillance and response. Moreover, global health security frame became important after 2001 bioterror and 2003 SARS outbreak. Consequently, international health regulation was fully revised in 2005, which included not only infectious disease but also public health emergency. The new international health regime was differently characterized in several aspects; reinforcement of global cooperation and surveillance, enlargement of the role of supranational and international agencies, and reorganization of national capacity. KNIH was reorganized with epidemic control and research since late 1990s. However, in 2004 Korea Center for Disease Control and Prevention(KCDC) was established as a disease control institution with combining quarantine and other functions after 2003 SARS outbreak. KCDC unified national function against infectious disease including prevention, protection, response and research, as a national representative in disease control. The

Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD.

Science.gov (United States)

Atasoy, Selen; Roseman, Leor; Kaelen, Mendel; Kringelbach, Morten L; Deco, Gustavo; Carhart-Harris, Robin L

2017-12-15

Recent studies have started to elucidate the effects of lysergic acid diethylamide (LSD) on the human brain but the underlying dynamics are not yet fully understood. Here we used 'connectome-harmonic decomposition', a novel method to investigate the dynamical changes in brain states. We found that LSD alters the energy and the power of individual harmonic brain states in a frequency-selective manner. Remarkably, this leads to an expansion of the repertoire of active brain states, suggestive of a general re-organization of brain dynamics given the non-random increase in co-activation across frequencies. Interestingly, the frequency distribution of the active repertoire of brain states under LSD closely follows power-laws indicating a re-organization of the dynamics at the edge of criticality. Beyond the present findings, these methods open up for a better understanding of the complex brain dynamics in health and disease.

public procurement, governance and economic growth

African Journals Online (AJOL)

GRACE

Development (OECD) sees public procurement ―as a strategic policy lever to advance ... financial markets and provision of advisory services to businesses and government. ... Procurement established by the Section 3 of the Act. The BPP is the ... present annual reports to the Minister on the public procurement processes;.

Demystifying governance and its role for transitions in urban social–ecological systems

Science.gov (United States)

T.A. Muñoz-Erickson; L.K. Campbell; D.L. Childers; J.M. Grove; D.M. Iwaniec; S.T.A. Pickett; Michelle Romolini; Erika S. Svendsen

2016-01-01

Governance is key to sustainable urban transitions. Governance is a system of social, power, and decision-making processes that acts as a key driver of resource allocation and use, yet ecologists even urban ecologists–seldom consider governance concepts in their work. Transitions to more sustainable futures are becoming increasingly important to the management of many...

Brain Injury-Induced Synaptic Reorganization in Hilar Inhibitory Neurons Is Differentially Suppressed by Rapamycin.

Science.gov (United States)

Butler, Corwin R; Boychuk, Jeffery A; Smith, Bret N

2017-01-01

Following traumatic brain injury (TBI), treatment with rapamycin suppresses mammalian (mechanistic) target of rapamycin (mTOR) activity and specific components of hippocampal synaptic reorganization associated with altered cortical excitability and seizure susceptibility. Reemergence of seizures after cessation of rapamycin treatment suggests, however, an incomplete suppression of epileptogenesis. Hilar inhibitory interneurons regulate dentate granule cell (DGC) activity, and de novo synaptic input from both DGCs and CA3 pyramidal cells after TBI increases their excitability but effects of rapamycin treatment on the injury-induced plasticity of interneurons is only partially described. Using transgenic mice in which enhanced green fluorescent protein (eGFP) is expressed in the somatostatinergic subset of hilar inhibitory interneurons, we tested the effect of daily systemic rapamycin treatment (3 mg/kg) on the excitability of hilar inhibitory interneurons after controlled cortical impact (CCI)-induced focal brain injury. Rapamycin treatment reduced, but did not normalize, the injury-induced increase in excitability of surviving eGFP+ hilar interneurons. The injury-induced increase in response to selective glutamate photostimulation of DGCs was reduced to normal levels after mTOR inhibition, but the postinjury increase in synaptic excitation arising from CA3 pyramidal cell activity was unaffected by rapamycin treatment. The incomplete suppression of synaptic reorganization in inhibitory circuits after brain injury could contribute to hippocampal hyperexcitability and the eventual reemergence of the epileptogenic process upon cessation of mTOR inhibition. Further, the cell-selective effect of mTOR inhibition on synaptic reorganization after CCI suggests possible mechanisms by which rapamycin treatment modifies epileptogenesis in some models but not others.

Effects of social reorganization on dopamine D2/D3 receptor availability and cocaine self-administration in male cynomolgus monkeys.

Science.gov (United States)

Czoty, P W; Gould, R W; Gage, H D; Nader, M A

2017-09-01

Studies have demonstrated that brain dopamine D2/D3 receptors (D2/D3R) and the reinforcing effects of cocaine can be influenced by a monkey's position in the social dominance hierarchy. In this study, we manipulated the social ranks of monkeys by reorganizing social groups and assessed effects on D2/D3R availability and cocaine self-administration. Male cynomolgus monkeys (N = 12) had been trained to self-administer cocaine under a concurrent cocaine-food reinforcement schedule. Previously, PET measures of D2/D3R availability in the caudate nucleus and putamen had been obtained with [ 18 F]fluoroclebopride during cocaine abstinence, while monkeys lived in stable social groups of four monkeys/pen. For this study, monkeys were reorganized into groups that consisted of (1) four previously dominant, (2) four previously subordinate, and (3) a mix of previously dominant and subordinate monkeys. After 3 months, D2/D3R availability was redetermined and cocaine self-administration was reexamined. D2/D3R availability significantly increased after reorganization in monkeys who were formerly subordinate, with the greatest increases observed in those that became dominant. No consistent changes in D2/D3R availability were observed in formerly dominant monkeys. Cocaine self-administration did not vary according to rank after reorganization of social groups. However, when compared to their previous cocaine self-administration data, the potency of cocaine as a reinforcer decreased in 9 of 11 monkeys. These results indicate that changing the social conditions can alter D2/D3R availability in subordinate monkeys in a manner suggestive of environmental enrichment. In most monkeys, social reorganization shifted the cocaine dose-response curve to the right, also consistent with environmental enrichment.

13 CFR 108.470 - SBA approval of merger, consolidation, or reorganization of NMVC Company.

Science.gov (United States)

2010-01-01

... BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Changes in Ownership, Structure, or Control Change in Structure of Nmvc Company § 108.470 SBA approval of merger, consolidation, or reorganization of NMVC Company. You may not merge, consolidate, change form of organization (corporation or...

77 FR 27151 - Implementing the Freedom of Information Act

Science.gov (United States)

2012-05-09

... Memoranda on ``The Freedom of Information Act'' and ``Transparency and Open Government,'' as well as... OFFICE OF SCIENCE AND TECHNOLOGY POLICY 32 CFR Part 2403 Implementing the Freedom of Information... Policy (OSTP) is proposing to issue regulations implementing the Freedom of Information Act (FOIA). The...

25 CFR 1000.14 - Who is eligible to participate in Tribal self-governance?

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Who is eligible to participate in Tribal self-governance...-DETERMINATION AND EDUCATION ACT Selection of Additional Tribes for Participation in Tribal Self-Governance Eligibility § 1000.14 Who is eligible to participate in Tribal self-governance? Two types of entities are...

78 FR 9749 - Notice of Sunshine Act Meeting

Science.gov (United States)

2013-02-11

... to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and... to approve the 2013 budget of the Public Company Accounting Oversight Board and will consider the related annual accounting support fee for the Board under Section 109 of the Sarbanes-Oxley Act of 2002...

Government of Canada Initiatives in Support of the Joint Convention

International Nuclear Information System (INIS)

Brown, P.A.; Metcalfe, D.E.; Lojk, R.

2006-01-01

The Government of Canada strongly supported international efforts to bring into force the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management (the Joint Convention), and was the second country to ratify it. The Joint Convention places a number of obligations on Contracting Parties aimed at achieving and maintaining a high level of safety worldwide in spent fuel and radioactive waste management, ensuring that effective defenses against potential hazards are in place during all management stages, preventing accidents with radiological consequences and mitigating their consequences should they occur. In addition to establishing and maintaining a modem regulatory framework and an independent regulatory body through the 2000 Nuclear Safety and Control Act, the Government of Canada has implemented a number of initiatives that address its responsibilities and serve to further enhance Canada's compliance with the Joint Convention. For nuclear fuel waste, the Government of Canada brought into force the Nuclear Fuel Waste Act in 2002 to require waste owners to develop, fund, organize and implement a long-term solution for Canada's nuclear fuel waste. The Act clearly reserves for Government the decision on the solution to be implemented in the best interests of Canadians, as well as oversight to ensure that waste owners are fulfilling their responsibilities. In the case of low-level radioactive waste, long-term solutions are being developed to ensure the protection of health, safety, and the environment, both now and in the future. Regarding uranium mine and mill tailings, current operators have state-of-the-art waste management facilities in place. The Government of Canada works with provincial governments to ensure that any potential abandoned or legacy mines sites where no owner can be held responsible are safely decommissioned and managed over the long term. (authors)

Government Policies for Corporate Social Responsibility in Europe

DEFF Research Database (Denmark)

Knudsen, Jette Steen; Moon, Jeremy; Slager, Rieneke

This paper analyses policies of twenty two EU member governments designed to encourage corporate social responsibility (CSR) over the first decade of the century. Our paper categorizes policies for CSR into different types depending on their expected degree of regulatory strength. Secondly, whilst...... it identifies a wide range of issues to which government CSR policies are directed, it notes a tendency for these to have expanded from social affairs and employment issues, through environmental issues, to economic and trade and development issues. Thirdly, governments act as agents in their respective...... institutional structures to embed CSR concerns explicitly into these frameworks....

Dynamic functional reorganizations and relationship with working memory performance in healthy aging.

Directory of Open Access Journals (Sweden)

Roser eSala-Llonch

2012-06-01

Full Text Available In recent years, several theories have been proposed in attempts to identify the neural mechanisms underlying successful cognitive aging. Old subjects show increased neural activity during the performance of tasks, mainly in prefrontal areas, which is interpreted as a compensatory mechanism linked to functional brain efficiency. Moreover, resting-state studies have concluded that elders show disconnection or disruption of large-scale functional networks. We used functional MRI during resting-state and a verbal n-back task with different levels of memory load in a cohort of young and old healthy adults to identify patterns of networks associated with working memory and brain default mode. We found that the disruption of resting-state networks in the elderly coexists with task-related overactivations of certain brain areas and with reorganizations within these functional networks. Moreover, elders who were able to activate additional areas and to recruit a more bilateral frontal pattern within the task-related network achieved successful performance on the task. We concluded that the balanced and plastic reorganization of brain networks underlies successful cognitive aging. This observation allows the integration of several theories that have been proposed to date regarding the aging brain.

Enacting localist health policy in the English NHS: the 'governing assemblage' of Clinical Commissioning Groups.

Science.gov (United States)

Hammond, Jonathan; Coleman, Anna; Checkland, Kath

2018-01-01

Objectives The Health and Social Care Act 2012 introduced Clinical Commissioning Groups to take responsibility for commissioning (i.e. planning and purchasing) the majority of services for local populations in the English NHS. Constituted as 'membership organizations', with membership compulsory for all GP practices, Clinical Commissioning Groups are overseen by, and are accountable to, a new arm's-length body, NHS England. This paper critically engages with the content and policy narrative of the 2012 Act and explores this in relation to the reality of local policy enactment. Methods Set against a careful review of the 2012 Act, a case study of a nascent Clinical Commissioning Groups was conducted. The research included observations of Clinical Commissioning Group meetings and events (87 h), and in-depth interviews (16) with clinical commissioners, GPs, and managers. Results The 2012 Act was presented as part of a broader government agenda of decentralization and localism. Clinical Commissioning Group membership organizations were framed as a means of better meeting the needs and preferences of local patients and realizing a desirable increase in localism. The policy delineated the 'governing body' and 'the membership', with the former elected from/by the latter to oversee the organization. 'The membership' was duty bound to be 'good', engaged members and to represent their patients' interests. Fieldwork with Notchcroft Clinical Commissioning Group revealed that Clinical Commissioning Groups' statutory duty to NHS England to 'ensure the continuous improvement' of GP practice members involved performance scrutiny of GP practices. These governance processes were carried out by a varied cast of individuals, many of whom did not fit into the binary categorization of membership and governing body constructed in the policy. A concept, the governing assemblage, was developed to describe the dynamic cast of people involved in shaping the work and direction of the Clinical

Internet Governance amp Cyber Crimes In UAE

OpenAIRE

Ayesha Al Neyadi; Alia Al Kaabi; Laila Al Kaabi; Mariam Al Ghufli; Maitha Al Shamsi; Dr. Muhammad Khan

2015-01-01

Abstract Most people in UAE dont feel safe while they are use the Internet because most internet users have been a victim for cyber crime. Cyber crime threat rate has increased which has targeted on citizen privacy property and governments also the reputation problems. There are many criminal activities such as indecent acts Copyright issues Terrorist Acts State security and Contempt of religion. Cyber crimes due to several reasons such as they have lack of social intelligence they are being ...

CONCEPTS OF THE REORGANIZATION OF SERVICE PROCESSES

Directory of Open Access Journals (Sweden)

Dóra DOBÁK

2016-12-01

Full Text Available In this article the literature based review of the developing of (logistificated business processes and their reorganizations are shown briefly. The research of the service processes is also actual in our time giving work to managers and researches alike. In the narrowing market the increasing competition and the dominance of customers is a warning to the companies to carry out continuous rationalization and reductions of costs in order to increase efficiency. In this essay we would like to show briefly how we started our research primarily concentrating on technical literatures. First of all we concentrate on the improvement assets of processes. We will show some major tendencies in the process of Business Process Amelioration (BPA evolution. The production focused approach of services can mean significant process improvement therefore it is a good analysis method of the process improvement.

25 CFR 1000.220 - What regulations apply to self-governance Tribes?

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false What regulations apply to self-governance Tribes? 1000.220 Section 1000.220 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.220 What regulations apply to self-governance...

Annual Report to Parliament Access to Information Act International ...

International Development Research Centre (IDRC) Digital Library (Canada)

leonardi

Part 6: Completion time of consultations on Cabinet confidences . ... The Act gives Canadian citizens and permanent residents the right to have access to federal government ... The ATIP Coordinator works with IDRC's Information Management .... to its employees on the Act. However, a training program was developed and.

Corrado Pettenati acting head of ETT

CERN Multimedia

2004-01-01

Following the departure of Juan Antonio Rubio, Corrado Pettenati has been appointed as the acting head of the ETT unit with effect from 1 August. He joined CERN in 1995 as head librarian, reorganizing and modernizing the library before becoming deputy leader of ETT from June 2000 to April 2004. Previously, he worked at the European University Institute in Florence from 1976, developing automated library systems and becoming head of the computer centre in 1985. He has also been a software analyst and a telecommunications specialist. In 2003 he was appointed as member of the steering committee of the Cellule de Coordination Documentaire Nationale pour les Mathématiques de Grenoble, and in 2004 became a member of the EULER - European Libraries and Electronic Resources in Mathematical Sciences - Scientific Advisory Board, based in Germany. He was born in 1946 and graduated with a degree in Electrical Engineering from the Polytechnic in Milan in 1969.

Convincing governments to act: VISION 2020 and the Millennium Development Goals

OpenAIRE

Faal, Hannah; Gilbert, Clare

2007-01-01

Many countries have signed the declaration of VISION 2020: The Right to Sight and have established national committees for the prevention of blindness. However, some governments still need to be convinced to allocate the resources needed to achieve the objectives of VISION 2020.

Unilateral hearing during development: hemispheric specificity in plastic reorganizations.

Science.gov (United States)

Kral, Andrej; Heid, Silvia; Hubka, Peter; Tillein, Jochen

2013-01-01

The present study investigates the hemispheric contributions of neuronal reorganization following early single-sided hearing (unilateral deafness). The experiments were performed on ten cats from our colony of deaf white cats. Two were identified in early hearing screening as unilaterally congenitally deaf. The remaining eight were bilaterally congenitally deaf, unilaterally implanted at different ages with a cochlear implant. Implanted animals were chronically stimulated using a single-channel portable signal processor for two to five months. Microelectrode recordings were performed at the primary auditory cortex under stimulation at the hearing and deaf ear with bilateral cochlear implants. Local field potentials (LFPs) were compared at the cortex ipsilateral and contralateral to the hearing ear. The focus of the study was on the morphology and the onset latency of the LFPs. With respect to morphology of LFPs, pronounced hemisphere-specific effects were observed. Morphology of amplitude-normalized LFPs for stimulation of the deaf and the hearing ear was similar for responses recorded at the same hemisphere. However, when comparisons were performed between the hemispheres, the morphology was more dissimilar even though the same ear was stimulated. This demonstrates hemispheric specificity of some cortical adaptations irrespective of the ear stimulated. The results suggest a specific adaptation process at the hemisphere ipsilateral to the hearing ear, involving specific (down-regulated inhibitory) mechanisms not found in the contralateral hemisphere. Finally, onset latencies revealed that the sensitive period for the cortex ipsilateral to the hearing ear is shorter than that for the contralateral cortex. Unilateral hearing experience leads to a functionally-asymmetric brain with different neuronal reorganizations and different sensitive periods involved.

40 CFR 2.301 - Special rules governing certain information obtained under the Clean Air Act.

Science.gov (United States)

2010-07-01

... the Act (except a provision of Part II of the Act with respect to a manufacturer of new motor vehicles or new motor vehicle engines); (ii) Provided or obtained under section 208 of the Act, 42 U.S.C. 7542... of papers, books, or documents issued under the authority of section 307(a) of the Act, 42 U.S.C...

Theoretical calculation of reorganization energy for electron self-exchange reaction by constrained density functional theory and constrained equilibrium thermodynamics.

Science.gov (United States)

Ren, Hai-Sheng; Ming, Mei-Jun; Ma, Jian-Yi; Li, Xiang-Yuan

2013-08-22

Within the framework of constrained density functional theory (CDFT), the diabatic or charge localized states of electron transfer (ET) have been constructed. Based on the diabatic states, inner reorganization energy λin has been directly calculated. For solvent reorganization energy λs, a novel and reasonable nonequilibrium solvation model is established by introducing a constrained equilibrium manipulation, and a new expression of λs has been formulated. It is found that λs is actually the cost of maintaining the residual polarization, which equilibrates with the extra electric field. On the basis of diabatic states constructed by CDFT, a numerical algorithm using the new formulations with the dielectric polarizable continuum model (D-PCM) has been implemented. As typical test cases, self-exchange ET reactions between tetracyanoethylene (TCNE) and tetrathiafulvalene (TTF) and their corresponding ionic radicals in acetonitrile are investigated. The calculated reorganization energies λ are 7293 cm(-1) for TCNE/TCNE(-) and 5939 cm(-1) for TTF/TTF(+) reactions, agreeing well with available experimental results of 7250 cm(-1) and 5810 cm(-1), respectively.

76 FR 70709 - Sunshine Act Meeting; Emergency Meeting Notice

Science.gov (United States)

2011-11-15

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meeting; Emergency Meeting Notice This notice that an emergency meeting was held is published pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, 5 U.S.C. 552b. AGENCY HOLDING THE MEETING: Commodity Futures Trading...

Reorganization in processing of spectral and temporal input in the rat posterior auditory field induced by environmental enrichment

Science.gov (United States)

Jakkamsetti, Vikram; Chang, Kevin Q.

2012-01-01

Environmental enrichment induces powerful changes in the adult cerebral cortex. Studies in primary sensory cortex have observed that environmental enrichment modulates neuronal response strength, selectivity, speed of response, and synchronization to rapid sensory input. Other reports suggest that nonprimary sensory fields are more plastic than primary sensory cortex. The consequences of environmental enrichment on information processing in nonprimary sensory cortex have yet to be studied. Here we examine physiological effects of enrichment in the posterior auditory field (PAF), a field distinguished from primary auditory cortex (A1) by wider receptive fields, slower response times, and a greater preference for slowly modulated sounds. Environmental enrichment induced a significant increase in spectral and temporal selectivity in PAF. PAF neurons exhibited narrower receptive fields and responded significantly faster and for a briefer period to sounds after enrichment. Enrichment increased time-locking to rapidly successive sensory input in PAF neurons. Compared with previous enrichment studies in A1, we observe a greater magnitude of reorganization in PAF after environmental enrichment. Along with other reports observing greater reorganization in nonprimary sensory cortex, our results in PAF suggest that nonprimary fields might have a greater capacity for reorganization compared with primary fields. PMID:22131375

The Great Whale review and the federal government's disappearing act

International Nuclear Information System (INIS)

Fenge, T.

1991-01-01

After considerable political and legal pressure, the Canadian and Quebec governments, plus the electric utility Hydro-Quebec, agreed to a global review and environmental assessment of the Great Whale hydroelectric project in northern Quebec. The assessment is being handled by five committees, each covering distinct areas of geography and responsibility. The initial task of the review committees was to determine the scope of the assessment, and 23 days of public hearings were held in northern and southern Quebec and on the Belcher Islands. The federal government's absence from the scoping hearings was a curious development, since federal agencies normally participate actively in such hearings. A federal guidelines order upheld recently by the Canadian Supreme Court requires federal participation in environmental assessment processes. The Great Whale project affects areas of federal jurisdiction as well as areas outside Quebec, and federal expertise in such matters as the marine environment is crucial in airing environmental issues related to the project. Interviews with federal officials on the reasons for federal absence are summarized. It is concluded that the federal agencies did not really regard scoping hearings as part of the public review, and that this review does not start until hearings begin on the environmental impact statement

Patterns of structural reorganization of the corticospinal tract in children with Sturge-Weber syndrome

Science.gov (United States)

Kamson, David O.; Juhász, Csaba; Shin, Joseph; Behen, Michael E.; Guy, William C.; Chugani, Harry T.; Jeong, Jeong-Won

2014-01-01

Background Reorganization of the corticospinal tract (CST) after early damage can limit motor deficit. In this study, we explored patterns of structural CST reorganization in children with Sturge-Weber syndrome. Methods Five children (age 1.5-7 years) with motor deficit due to unilateral Sturge-Weber syndrome were studied prospectively and longitudinally (1-2 years follow-up). CST segments belonging to hand and leg movements were separated, and their volume was measured by diffusion tensor imaging (DTI) tractography using a recently validated method. CST segmental volumes were normalized and compared between the SWS children and age-matched healthy controls. Volume changes during follow-up were also compared to clinical motor symptoms. Results In the SWS children, hand-related (but not leg-related) CST volumes were consistently decreased in the affected cerebral hemisphere at baseline. At follow-up, two distinct patterns of hand CST volume changes emerged: (i) Two children with extensive frontal lobe damage showed a CST volume decrease in the lesional hemisphere and a concomitant increase in the non-lesional (contralateral) hemisphere. These children developed good hand grasp but no fine motor skills. (ii) The three other children, with relative sparing of the frontal lobe, showed an interval increase of the normalized hand CST volume in the affected hemisphere; these children showed no gross motor deficit at follow-up. Conclusions DTI tractography can detect differential abnormalities in the hand CST segment both ipsi- and contralateral to the lesion. Interval increase in the CST hand segment suggests structural reorganization, whose pattern may determine clinical motor outcome and could guide strategies for early motor intervention. PMID:24507695

The 'Hub Disruption Index', a reliable index sensitive to the brain networks reorganization. A study of the contralesional hemisphere in stroke

Directory of Open Access Journals (Sweden)

Maite Termenon

2016-08-01

Full Text Available Stroke, resulting in focal structural damage, induces changes in brain function at both local and global levels. Following stroke, cerebral networks present structural and functional reorganization to compensate for the dysfunctioning provoked by the lesion itself and its remote effects. As some recent studies underlined the role of the contralesional hemisphere during recovery, we studied its role %of the contralesional hemispherein the reorganization of brain function of stroke patients using resting state fMRI and graph theory. We explored this reorganization using the 'hub disruption index' (kappa, a global index sensitive to the reorganization of nodes within the graph. For a given graph metric, kappa of a subject corresponds to the slope of the linear regression model between the mean local network measures of a reference group, and the difference between that reference and the subject under study. In order to translate the use of kappa in clinical context, a prerequisite to achieve meaningful results is to investigate the reliability of this index. In a preliminary part, we studied the reliability of kappa by computing the intraclass correlation coefficient in a cohort of 100 subjects from the Human Connectome Project. Then, we measured intra-hemispheric kappa index in the contralesional hemisphere of 20 subacute stroke patients compared to 20 age-matched healthy controls. Finally, due to the small number of patients, we tested the robustness of our results repeating the experiment 1000 times by bootstrapping on the Human Connectome Project database. Statistical analysis showed a significant reduction of kappa for the contralesional hemisphere of right stroke patients compared to healthy controls. Similar results were observed for the right contralesional hemisphere of left stroke patients. We showed that kappa, is more reliable than global graph metrics and more sensitive to detect differences between groups of patients as compared to

Convincing governments to act: VISION 2020 and the Millennium Development Goals

Directory of Open Access Journals (Sweden)

Hannah Faal

2007-12-01

Full Text Available Many countries have signed the declaration of VISION 2020: The Right to Sight and have established national committees for the prevention of blindness. However, some governments still need to be convinced to allocate the resources needed to achieve the objectives of VISION 2020.

Specified radioactive waste final disposal act

International Nuclear Information System (INIS)

Yasui, Masaya

2001-01-01

Radioactive wastes must be finally and safely disposed far from human activities. Disposal act is a long-range task and needs to be understood and accepted by public for site selection. This paper explains basic policy of Japanese Government for final disposal act of specified radioactive wastes, examination for site selection guidelines to promote residential understanding, general concept of multi-barrier system for isolating the specific radioactive wastes, and research and technical development for radioactive waste management. (S. Ohno)

Permian-Triassic Tethyan realm reorganization: Implications for the outward Pangea margin

Science.gov (United States)

Riel, Nicolas; Jaillard, Etienne; Martelat, Jean-Emmanuel; Guillot, Stéphane; Braun, Jean

2018-01-01

We present a new conceptual model to explain the first order Permian-Triassic evolution of the whole > 30 000 km long Pangea margin facing the Panthalassa ocean. Compilation of available geological, geochemical, geochronogical and paleomagnetic data all along this system allowed us to distinguish three part of the margin: western Laurentia, western Gondwana and eastern Gondwana. These segments record distinct tectonic and magmatic events, which all occur synchronously along the whole margin and correlate well with the main geodynamic events of this period, i.e. subduction of the Paleotethys mid-ocean ridge at 310-280 Ma, opening of the Neotethys at 280-260 Ma, counterclockwise rotation of Pangea at 260-230 Ma and closure of the Paleotethys at 230-220 Ma. Between 260 and 230 Ma, the reorganization of the Tethyan realm triggered the up to 35° rotation of Pangea around an Euler pole located in northernmost South America. This implied both an increase and a decrease of the convergence rate between the margin and the Panthalassa ocean, north and south of the Euler pole, respectively. Thus, the Permian-Triassic Pangean margin was marked: in western Laurentia by marginal sea closure, in western Gondwana by widespread bimodal magmatic and volcanic activity, in eastern Gondwana by transpressive orogenic phase. Therefore, we propose that the Permian-Triassic evolution of the outward margin of Pangea was controlled by the Tethyan realm reorganization.

Long-Lasting Crossmodal Cortical Reorganization Triggered by Brief Postnatal Visual Deprivation.

Science.gov (United States)

Collignon, Olivier; Dormal, Giulia; de Heering, Adelaide; Lepore, Franco; Lewis, Terri L; Maurer, Daphne

2015-09-21

Animal and human studies have demonstrated that transient visual deprivation early in life, even for a very short period, permanently alters the response properties of neurons in the visual cortex and leads to corresponding behavioral visual deficits. While it is acknowledged that early-onset and longstanding blindness leads the occipital cortex to respond to non-visual stimulation, it remains unknown whether a short and transient period of postnatal visual deprivation is sufficient to trigger crossmodal reorganization that persists after years of visual experience. In the present study, we characterized brain responses to auditory stimuli in 11 adults who had been deprived of all patterned vision at birth by congenital cataracts in both eyes until they were treated at 9 to 238 days of age. When compared to controls with typical visual experience, the cataract-reversal group showed enhanced auditory-driven activity in focal visual regions. A combination of dynamic causal modeling with Bayesian model selection indicated that this auditory-driven activity in the occipital cortex was better explained by direct cortico-cortical connections with the primary auditory cortex than by subcortical connections. Thus, a short and transient period of visual deprivation early in life leads to enduring large-scale crossmodal reorganization of the brain circuitry typically dedicated to vision. Copyright © 2015 Elsevier Ltd. All rights reserved.

Congenital blindness is associated with large-scale reorganization of anatomical networks.

Science.gov (United States)

Hasson, Uri; Andric, Michael; Atilgan, Hicret; Collignon, Olivier

2016-03-01

Blindness is a unique model for understanding the role of experience in the development of the brain's functional and anatomical architecture. Documenting changes in the structure of anatomical networks for this population would substantiate the notion that the brain's core network-level organization may undergo neuroplasticity as a result of life-long experience. To examine this issue, we compared whole-brain networks of regional cortical-thickness covariance in early blind and matched sighted individuals. This covariance is thought to reflect signatures of integration between systems involved in similar perceptual/cognitive functions. Using graph-theoretic metrics, we identified a unique mode of anatomical reorganization in the blind that differed from that found for sighted. This was seen in that network partition structures derived from subgroups of blind were more similar to each other than they were to partitions derived from sighted. Notably, after deriving network partitions, we found that language and visual regions tended to reside within separate modules in sighted but showed a pattern of merging into shared modules in the blind. Our study demonstrates that early visual deprivation triggers a systematic large-scale reorganization of whole-brain cortical-thickness networks, suggesting changes in how occipital regions interface with other functional networks in the congenitally blind. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

U.S. Government Financial Statements: FY 2000 Reporting Underscores the Need to Accelerate Federal Financial Management Reform

National Research Council Canada - National Science Library

Walker, David

2001-01-01

.... In passing the 1990 Chief Financial Officers (CFO) Act and other financial management reform legislation, such as the Government Management Reform Act and the Federal Financial Management Improvement Act (FFMIA...

Tenth act amending the German atomic energy act

International Nuclear Information System (INIS)

Heller, W.

2009-01-01

On January 14, 2009, the German federal government introduced into parliament the 10th Act Amending the Atomic Energy Act. In the first reading in the federal parliament, Federal Minister for the Environment Gabriel emphasized 2 main points: Intensified protection of nuclear facilities and of transports of radioactive substances against unauthorized interventions; transfer by law to the Federal Office for Radiological Protection (BfS) of decommissioning of the Asse mine. Reliability review: The amendment to Sec.12 b of the Atomic Energy Act is to meet the different safety and security conditions after the terrorist attacks on September 11, 2001 in the United States and other terrorist activities afterwards (London, Madrid) also with respect to hazards arising to nuclear facilities and nuclear transports. The bill must be seen in conjunction with the Ordinance on Reliability Reviews under the Atomic Energy Act dated July 1, 1999 which covers reviews of reliability of persons holding special responsibilities. Asse II mine: The competence of the Federal Office for Radiological Protection is achieved by an amendment to Sec.23, Para.1, Number 2, Atomic Energy Act, in which the words ''and for the Asse II mine'' are added after the word ''waste.'' Further proceedings depend on the additional provision in a new Sec.57 b, Atomic Energy Act. Accordingly, the operation and decommissioning of the Asse II mine are subject to the regulations applicable to facilities of the federation pursuant to Sec.9a, Para.3. In this way, Asse II is given the same legal status as the federal waste management facilities. Moreover, it is stipulated that the mine is to be shut down immediately. (orig.)

Act 25/1964 of 29 April on nuclear energy

International Nuclear Information System (INIS)

1964-01-01

This outline Act governs all nuclear activities in Spain. It lays down all the principles presently applicable for safety and protection against ionizing radiation and for third party liability for nuclear damage. The Act also regulates the licensing of nuclear installations and the possession and use of radioactive materials. (NEA) [fr

The intended purpose of the draft amendment of the Atomic Energy Act

International Nuclear Information System (INIS)

Preuss, U.K.

1994-01-01

The seventh amendments to the Atomic Energy Act may become the most sweeping and significant reform the German atomic energy laws have undergone: the suggested amendment will transform the character of the Atomic Energy Act from its present nature of a nuclear licensing system into a technology management and control instrument. The function of the Atomic Energy Act so far is to deal with the consequences of an established technology and its known, ambivalent effects: aspects such as waste management and the technical and economic consequences implied n the decommissioning of nuclear installations play a far bigger role than planning, construction and operation of new installations. It is only consequent in this respect to abolish the 'promotional purpose' of the Act. This will mean, however, that the Federal Government relinquishes its responsibility for development and management of nuclear technology, handling it over to the private plant owners and operators. The responsibility that will remain with the Federal Government in connection with nuclear technology is linked with the Government's duty to provide for protection of the citizens. (HP) [de

Dumping at Sea Act 1974

International Nuclear Information System (INIS)

1974-01-01

This Act enables the United Kingdom Government to ratify both the Oslo Convention of 1972 for the Prevention of Marine Pollution by Dumping from Ships and Aircraft and the London Convention of 1972 on the Prevention of Marine Pollution by Dumping of Wastes and Other Matter. (NEA) [fr

A review of energy conservation initiatives by the Government of India

International Nuclear Information System (INIS)

Nandi, Paritosh; Basu, Sujay

2008-01-01

Energy conservation is the need of the hour. The first oil shock of 1973 shook up the industrialized nations of the world and awakened them from the sleepy complacency of never-ending oil flow. It made them face the stark reality of the uncertainty in oil supply restoration and the fragility of the trade in oil. This was the time when many countries realized the urgent need for energy conservation. Notably, the wave of energy conservation had struck the Indian intelligentia 3 years earlier when a Fuel Policy Committee was set up by the Government of India in 1970, which finally bore fruits three decades hence in the form of enactment of the much awaited Energy Conservation Act, 2001 by the Government of India. This Act made provisions for setting up of the Bureau of Energy Efficiency, a body corporate incorporated under the Act, for supervising and monitoring the efforts on energy conservation in India. In this article the stages in the historical development of Energy Conservation in India, the Government initiatives taken in this regard and the reasons for the limited success in implementation of conservation policies in the past have been discussed. (author)

Corticospinal Reorganization after Locomotor Training in a Person with Motor Incomplete Paraplegia

Directory of Open Access Journals (Sweden)

Nupur Hajela

2013-01-01

Full Text Available Activity-dependent plasticity as a result of reorganization of neural circuits is a fundamental characteristic of the central nervous system that occurs simultaneously in multiple sites. In this study, we established the effects of subthreshold transcranial magnetic stimulation (TMS over the primary motor cortex region on the tibialis anterior (TA long-latency flexion reflex. Neurophysiological tests were conducted before and after robotic gait training in one person with a motor incomplete spinal cord injury (SCI while at rest and during robotic-assisted stepping. The TA flexion reflex was evoked following nonnociceptive sural nerve stimulation and was conditioned by TMS at 0.9 TA motor evoked potential resting threshold at conditioning-test intervals that ranged from 70 to 130 ms. Subthreshold TMS induced a significant facilitation on the TA flexion reflex before training, which was reversed to depression after training with the subject seated at rest. During stepping, corticospinal facilitation of the flexion reflex at early and midstance phases before training was replaced with depression at early and midswing followed by facilitation at late swing after training. These results constitute the first neurophysiologic evidence that locomotor training reorganizes the cortical control of spinal interneuronal circuits that generate patterned motor activity, modifying spinal reflex function, in the chronic lesioned human spinal cord.

From network structure to network reorganization: implications for adult neurogenesis

International Nuclear Information System (INIS)

Schneider-Mizell, Casey M; Zochowski, Michal R; Sander, Leonard M; Parent, Jack M; Ben-Jacob, Eshel

2010-01-01

Networks can be dynamical systems that undergo functional and structural reorganization. One example of such a process is adult hippocampal neurogenesis, in which new cells are continuously born and incorporate into the existing network of the dentate gyrus region of the hippocampus. Many of these introduced cells mature and become indistinguishable from established neurons, joining the existing network. Activity in the network environment is known to promote birth, survival and incorporation of new cells. However, after epileptogenic injury, changes to the connectivity structure around the neurogenic niche are known to correlate with aberrant neurogenesis. The possible role of network-level changes in the development of epilepsy is not well understood. In this paper, we use a computational model to investigate how the structural and functional outcomes of network reorganization, driven by addition of new cells during neurogenesis, depend on the original network structure. We find that there is a stable network topology that allows the network to incorporate new neurons in a manner that enhances activity of the persistently active region, but maintains global network properties. In networks having other connectivity structures, new cells can greatly alter the distribution of firing activity and destroy the initial activity patterns. We thus find that new cells are able to provide focused enhancement of network only for small-world networks with sufficient inhibition. Network-level deviations from this topology, such as those caused by epileptogenic injury, can set the network down a path that develops toward pathological dynamics and aberrant structural integration of new cells

Radiation Act, promulgated on May 8,1997

International Nuclear Information System (INIS)

1997-01-01

The Radiation Act was passed by the Estonian Parliament on 23 Apr 1997 and promulgated by the President on 8 May 1997. It is the principal legal instrument in the field of radiation protection for workers, the public and the environment. The Act is based on the concepts, principles, terminology and dose limits stipulated in the Basic Safety Standards (IAEA Safety Series No. 115-1) and the EC Directive 96/29/EURATOM. The Radiation Act defines the institutional framework for, and establishes the rules applicable to, the use of ionising radiation, the detention of radiation sources, the transport of radioactive materials, radioactive waste disposal and other activities which cause or may cause harm to health or to the environment. It also contains some general provisions on radioactive waste management, import and export of such wastes and the prohibition against importing radioactive waste for disposal purposes. The Act deals solely with radiation protection; all other nuclear activities are to be covered by other specific laws. The Estonian Radiation Protection Centre is empowered under the Act to inspect sources of radiation exposure and to register dose and source data. It is generally responsible for enforcing the provisions of the Act, although the details of the medical checks for radiation workers are governed by rules established by the Minister for Social Affairs. Chapter 3 of the Radiation Act contains detailed provisions on dose limits for the following categories of exposure to ionising radiation. The Act provides that Government and nominated Ministers be empowered to enact implementing regulations on exemption levels, requirements to ensure observance of the stipulated dose limits, qualification procedures for radiation workers, medical checks of radiation workers, medical applications of ionising radiation, packaging and safety procedures for radiation sources and rules for handling radioactive waste

Cortical Reorganization in Dual Innervation by Single Peripheral Nerve.

Science.gov (United States)

Zheng, Mou-Xiong; Shen, Yun-Dong; Hua, Xu-Yun; Hou, Ao-Lin; Zhu, Yi; Xu, Wen-Dong

2017-09-21

Functional recovery after peripheral nerve injury and repair is related with cortical reorganization. However, the mechanism of innervating dual targets by 1 donor nerve is largely unknown. To investigate the cortical reorganization when the phrenic nerve simultaneously innervates the diaphragm and biceps. Total brachial plexus (C5-T1) injury rats were repaired by phrenic nerve-musculocutaneous nerve transfer with end-to-side (n = 15) or end-to-end (n = 15) neurorrhaphy. Brachial plexus avulsion (n = 5) and sham surgery (n = 5) rats were included for control. Behavioral observation, electromyography, and histologic studies were used for confirming peripheral nerve reinnervation. Cortical representations of the diaphragm and reinnervated biceps were studied by intracortical microstimulation techniques before and at months 0.5, 3, 5, 7, and 10 after surgery. At month 0.5 after complete brachial plexus injury, the motor representation of the injured forelimb disappeared. The diaphragm representation was preserved in the "end-to-side" group but absent in the "end-to-end" group. Rhythmic contraction of biceps appeared in "end-to-end" and "end-to-side" groups, and the biceps representation reappeared in the original biceps and diaphragm areas at months 3 and 5. At month 10, it was completely located in the original biceps area in the "end-to-end" group. Part of the biceps representation remained in the original diaphragm area in the "end-to-side" group. Destroying the contralateral motor cortex did not eliminate respiration-related contraction of biceps. The brain tends to resume biceps representation from the original diaphragm area to the original biceps area following phrenic nerve transfer. The original diaphragm area partly preserves reinnervated biceps representation after end-to-side transfer. Copyright © 2017 by the Congress of Neurological Surgeons

Unilateral hearing during development: hemispheric specificity in plastic reorganizations

Directory of Open Access Journals (Sweden)

Andrej eKral

2013-11-01

Full Text Available The present study investigates the hemispheric contributions of neuronal reorganization following early single-sided hearing (unilateral deafness. The experiments were performed on ten cats from our colony of deaf white cats. Two were identified in early hearing screening as unilaterally congenitally deaf. The remaining eight were bilaterally congenitally deaf, unilaterally implanted at different ages with a cochlear implant. Implanted animals were chronically stimulated using a single-channel portable signal processor for two to five months. Microelectrode recordings were performed at the primary auditory cortex under stimulation at the hearing and deaf ear with bilateral cochlear implants. Local field potentials (LFPs were compared at the cortex ipsilateral and contralateral to the hearing ear. The focus of the study was on the morphology and the onset latency of the LFPs. The data revealed that effects of hearing experience were more pronounced when stimulating the hearing ear. With respect to morphology of LFPs, pronounced hemisphere-specific effects were observed. Morphology of amplitude-normalized LFPs for stimulation of the deaf and the hearing ear was similar for responses recorded at the same hemisphere. However, when comparisons were performed between the hemispheres, the morphology was more dissimilar even though the same ear was stimulated. This demonstrates hemispheric specificity of some cortical adaptations irrespective of the ear stimulated. The results suggest a specific adaptation process at the hemisphere ipsilateral to the hearing ear, involving specific (down-regulated inhibitory mechanisms not found in the contralateral hemisphere. Finally, onset latencies revealed that the sensitive period for the cortex ipsilateral to the hearing ear is shorter than that for the contralateral cortex. Unilateral hearing experience leads to a functionally-asymmetric brain with different neuronal reorganizations and different sensitive

Obstacles to the implementation of the Freedom of Information Act ...

African Journals Online (AJOL)

... implementation of the FOI Act, particularly non-compliance by government or public officials. The article recommends strategies to overcome these challenges and concludes that with political will, the objectives of the FOI Act will be realized. Keywords: Freedom of information, access, records, secrecy, Law, expression ...

Federal Advisory Committee Act (FACA) Database-Complete-Raw

Data.gov (United States)

General Services Administration — The Federal Advisory Committee Act (FACA) database is used by Federal agencies to continuously manage an average of 1,000 advisory committees government-wide. This...

Patterns of structural reorganization of the corticospinal tract in children with Sturge-Weber syndrome.

Science.gov (United States)

Kamson, David O; Juhász, Csaba; Shin, Joseph; Behen, Michael E; Guy, William C; Chugani, Harry T; Jeong, Jeong-Won

2014-04-01

Reorganization of the corticospinal tract after early damage can limit motor deficit. In this study, we explored patterns of structural corticospinal tract reorganization in children with Sturge-Weber syndrome. Five children (age 1.5-7 years) with motor deficit resulting from unilateral Sturge-Weber syndrome were studied prospectively and longitudinally (1-2 years follow-up). Corticospinal tract segments belonging to hand and leg movements were separated and their volume was measured by diffusion tensor imaging tractography using a recently validated method. Corticospinal tract segmental volumes were normalized and compared between the Sturge-Weber syndrome children and age-matched healthy controls. Volume changes during follow-up were also compared with clinical motor symptoms. In the Sturge-Weber syndrome children, hand-related (but not leg-related) corticospinal tract volumes were consistently decreased in the affected cerebral hemisphere at baseline. At follow-up, two distinct patterns of hand corticospinal tract volume changes emerged. (1) Two children with extensive frontal lobe damage showed a corticospinal tract volume decrease in the lesional hemisphere and a concomitant increase in the nonlesional (contralateral) hemisphere. These children developed good hand grasp but no fine motor skills. (2) The three other children, with relative sparing of the frontal lobe, showed an interval increase of the normalized hand corticospinal tract volume in the affected hemisphere; these children showed no gross motor deficit at follow-up. Diffusion tensor imaging tractography can detect differential abnormalities in the hand corticospinal tract segment both ipsi- and contralateral to the lesion. Interval increase in the corticospinal tract hand segment suggests structural reorganization, whose pattern may determine clinical motor outcome and could guide strategies for early motor intervention. Copyright © 2014 Elsevier Inc. All rights reserved.

75 FR 42377 - Foreign-Trade Zone 244-Riverside County, CA; Application for Reorganization Under Alternative...

Science.gov (United States)

2010-07-21

... application and case record and to report findings and recommendations to the Board. Public comment is invited...--Riverside County, CA; Application for Reorganization Under Alternative Site Framework An application has been submitted to the Foreign-Trade Zones (FTZ) Board (the Board) by the March Joint Powers Authority...

78 FR 60695 - Regulatory Reorganization; Administrative Changes to Regulations Due to the Consolidation of the...

Science.gov (United States)

2013-10-02

... Consolidation of the Financial Management Service and the Bureau of the Public Debt Into the Bureau of the... Service''). The new bureau consolidated the bureaus formerly known as the Financial Management Service... Register on May 24, 2013. This consolidation requires reorganization of, and administrative changes to...

76 FR 4865 - Reorganization of Foreign-Trade Zone 104 Under Alternative Site Framework Savannah, GA

Science.gov (United States)

2011-01-27

... Commission, grantee of Foreign-Trade Zone 104, submitted an application to the Board (FTZ Docket 51-2010... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1736] Reorganization of Foreign-Trade Zone 104 Under Alternative Site Framework Savannah, GA Pursuant to its authority under the Foreign...

The efficiency of government supervision

International Nuclear Information System (INIS)

Paetzold, H.

1992-01-01

In 1970, fires as events initiating plant failure were included in the accident analyses of nuclear power plant design concepts. In the meantime, they have been expressed in more precise terms and incorporated into the bodies of nuclear technical rules and regulations. Following a suggestion by the Baden-Wuerttemberg State Ministry for the Environment, the efficiency of government supervision has been examined for the example of fire protection measures or the site of Phillipsburg with one BWR and one PWR plant in operation. The result of the examination indicated that pragmatic approaches and the establishment of key areas of supervision could further enhance the efficiency of government supervision under Section 19 of the German Atomic Energy Act and achieve improvements in plant safety. (orig.) [de

EPA and the Federal Technology Transfer Act: Opportunity knocks

Energy Technology Data Exchange (ETDEWEB)

Gatchett, A.M.; Fradkin, L.; Moore, M.; Gorman, T.; Ehrlich, A. [Environmental Protection Agency, Washington, DC (United States)

1990-12-31

In 1986, the Federal Technology Transfer Act (FTTA) was established to promote a closer, collaborative relationship between federal government agencies and the private sector. With the increasing need for new cost-effective technologies to prevent and control pollution, both the US Environmental Protection Agency (EPA) and private industry are encouraged to facilitate the transfer of knowledge and technology under this Act. The FTTA removed several of the legal and institutional barriers to cooperative research that existed before the Act`s passage. Through the FTTA, the government strives to promote the movement of its products, processes, skills, and knowledge into the private sector for further development and commercialization by encouraging the exchange of technical personnel and the sharing of facilities and other resources. Collaborative efforts between industry, federal agencies, and academia are made possible through cooperative research and development agreements (CRADAs). Forty-two CRADAs and five licensing agreements have been initiated with EPA under this program. This paper provides an overview of this new and innovative program within the EPA. 1 fig., 2 tabs.

THE HIGHLY DEVELOPED INFORMATION AND EDUCATION ENVIRONMENT AS A PRECONDITION OF EDUCATIONAL SYSTEM REORGANIZATION

Directory of Open Access Journals (Sweden)

Y. K. Khenner

2014-01-01

Full Text Available The paper regards the development of the information and education environment of Russian universities as an important condition for successful reorganization of higher education. Taking as an example one of theUSuniversities, the author demonstrates the capacity of information education environment and its impact on the multilevel educational process. The comparative analysis of the existing information education environments of Russian an American universities reveals that such effective improvements as increasing number of students working on the individual curricula,__ implementation of the learning outcome monitoring, inclusive education, etc require immediate and substantial development of the information education environment of Russian universities. Both the development level and informational content of the environment in question remain unsatisfactory due to the financial, economic and staff related reasons. Consequently, the higher school reorganization is lagging behind retarded by the lack of synchronization between the attempts to improve the education quality and competitiveness on the one hand, and insufficient level of the information education environment characteristic of Russian universities on the other hand.

Nuclear substructure reorganization during late stageerythropoiesis is selective and does not involve caspase cleavage ofmajor nuclear substructural proteins

Energy Technology Data Exchange (ETDEWEB)

Krauss, Sharon Wald; Lo, Annie J.; Short, Sarah A.; Koury, MarkJ.; Mohandas, Narla; Chasis, Joel Anne

2005-04-06

Enucleation, a rare feature of mammalian differentiation, occurs in three cell types: erythroblasts, lens epithelium and keratinocytes. Previous investigations suggest that caspase activation functions in lens epithelial and keratinocyte enucleation, as well as in early erythropoiesis encompassing BFU-E differentiation to proerythroblast. To determine whether caspase activation contributes to later erythropoiesis and whether nuclear substructures other than chromatin reorganize, we analyzed distributions of nuclear subcompartment proteins and assayed for caspase-induced cleavage of subcompartmental target proteins in mouse erythroblasts. We found that patterns of lamin B in the filamentous network interacting with both the nuclear envelope and DNA, nuclear matrix protein NuMA, and splicing factors Sm and SC35 persisted during nuclear condensation, consistent with effective transcription of genes expressed late in differentiation. Thus nuclear reorganization prior to enucleation is selective, allowing maintenance of critical transcriptional processes independent of extensive chromosomal reorganization. Consistent with these data, we found no evidence for caspase-induced cleavage of major nuclear subcompartment proteins during late erythropoiesis, in contrast to what has been observed in early erythropoiesis and in lens epithelial and keratinocyte differentiation. These findings imply that nuclear condensation and extrusion during terminal erythroid differentiation involve novel mechanisms that do not entail major activation of apoptotic machinery.

Reorganization and stability for motor and language areas using cortical stimulation: case example and review of the literature.

Science.gov (United States)

Serafini, Sandra; Komisarow, Jordan M; Gallentine, William; Mikati, Mohamad A; Bonner, Melanie J; Kranz, Peter G; Haglund, Michael M; Grant, Gerald

2013-11-26

The cerebral organization of language in epilepsy patients has been studied with invasive procedures such as Wada testing and electrical cortical stimulation mapping and more recently with noninvasive neuroimaging techniques, such as functional MRI. In the setting of a chronic seizure disorder, clinical variables have been shown to contribute to cerebral language reorganization underscoring the need for language lateralization and localization procedures. We present a 14-year-old pediatric patient with a refractory epilepsy disorder who underwent two neurosurgical resections of a left frontal epileptic focus separated by a year. He was mapped extraoperatively through a subdural grid using cortical stimulation to preserve motor and language functions. The clinical history and extensive workup prior to surgery is discussed as well as the opportunity to compare the cortical maps for language, motor, and sensory function before each resection. Reorganization in cortical tongue sensory areas was seen concomitant with a new zone of ictal and interictal activity in the previous tongue sensory area. Detailed neuropsychological data is presented before and after any surgical intervention to hypothesize about the extent of reorganization between epochs. We conclude that intrahemispheric cortical plasticity does occur following frontal lobe resective surgery in a teenager with medically refractory seizures.

Reorganization and Stability for Motor and Language Areas Using Cortical Stimulation: Case Example and Review of the Literature

Directory of Open Access Journals (Sweden)

Sandra Serafini

2013-11-01

Full Text Available The cerebral organization of language in epilepsy patients has been studied with invasive procedures such as Wada testing and electrical cortical stimulation mapping and more recently with noninvasive neuroimaging techniques, such as functional MRI. In the setting of a chronic seizure disorder, clinical variables have been shown to contribute to cerebral language reorganization underscoring the need for language lateralization and localization procedures. We present a 14-year-old pediatric patient with a refractory epilepsy disorder who underwent two neurosurgical resections of a left frontal epileptic focus separated by a year. He was mapped extraoperatively through a subdural grid using cortical stimulation to preserve motor and language functions. The clinical history and extensive workup prior to surgery is discussed as well as the opportunity to compare the cortical maps for language, motor, and sensory function before each resection. Reorganization in cortical tongue sensory areas was seen concomitant with a new zone of ictal and interictal activity in the previous tongue sensory area. Detailed neuropsychological data is presented before and after any surgical intervention to hypothesize about the extent of reorganization between epochs. We conclude that intrahemispheric cortical plasticity does occur following frontal lobe resective surgery in a teenager with medically refractory seizures.

Brexit and government procurement

OpenAIRE

Dawar, Kamala

2017-01-01

This briefing paper looks at some of the legal issues that will affect the UK’s public procurement laws and policies following Brexit. For, once the UK revokes the European Communities Act 1972, it will no longer be obligated to follow the EU Procurement Directives, nor will it be subject to the commitments the EU has signed up to on behalf of the UK in the WTO Government Procurement Agreement (GPA) and in Preferential Trade Agreements (PTAs). Additionally, under the Devolution Settlement of ...

Transition Governance towards a Bioeconomy: A Comparison of Finland and The Netherlands

Directory of Open Access Journals (Sweden)

Rick Bosman

2016-10-01

Full Text Available In both Finland and The Netherlands strategies are being developed to switch from fossil to green resources in order to tackle the challenges of climate change and resource dependencies and to tap into the economic opportunities that arise. We investigated the similarities and differences in the transition process and governance strategies with respect to the transition towards a bioeconomy in both countries, using transition management as an evaluative lens. The research method involved comparative qualitative case study analysis through action research. We found that the governance approach in The Netherlands focusses on co-creating a long-term vision that informs for short-term action, on facilitating bottom-up regional clusters and promoting radical innovation through cooperation between vested players and frontrunners. Finland adopts a more traditional, top-down governance strategy, focussing on the shorter-term economic opportunities and incremental innovation that keep the overall structure of existing industries intact. We conclude that the Dutch government acts as a facilitator, while the Finnish government acts more as a director of the transition. We recommend that Finland’s governance for the bioeconomy be improved by applying insights from transition management, while the Dutch approach runs the risk of being captured by vested interests.

日本における企業集団税制改革の動向 : 企業組織再編税制と連結納税制度(第22回桃山学院大学・啓明大学校国際学術セミナー)

OpenAIRE

中田, 信正; Nobumasa, NAKATA; 本学経営学部

2002-01-01

The establishment of a taxation system to promote strategic business system reorganization is very important in Japan. The tax-free exchange and transfer of shares was introduced by the Tax Reform Act of 1999. Tax-free reorganization, enacted with the Tax Reform Act of 2001, includes mergers, corporate divisions, investments in kind and post-establishment transfers. The book value of the acquired corporation's property is carried over to the acquiring corporation in qualified reorganization. ...

Subcortical functional reorganization due to early blindness.

Science.gov (United States)

Coullon, Gaelle S L; Jiang, Fang; Fine, Ione; Watkins, Kate E; Bridge, Holly

2015-04-01

Lack of visual input early in life results in occipital cortical responses to auditory and tactile stimuli. However, it remains unclear whether cross-modal plasticity also occurs in subcortical pathways. With the use of functional magnetic resonance imaging, auditory responses were compared across individuals with congenital anophthalmia (absence of eyes), those with early onset (in the first few years of life) blindness, and normally sighted individuals. We find that the superior colliculus, a "visual" subcortical structure, is recruited by the auditory system in congenital and early onset blindness. Additionally, auditory subcortical responses to monaural stimuli were altered as a result of blindness. Specifically, responses in the auditory thalamus were equally strong to contralateral and ipsilateral stimulation in both groups of blind subjects, whereas sighted controls showed stronger responses to contralateral stimulation. These findings suggest that early blindness results in substantial reorganization of subcortical auditory responses. Copyright © 2015 the American Physiological Society.

Strategic Environmental Assessment of the Kenya Forests Act 2005

OpenAIRE

World Bank

2007-01-01

Forest in Kenya is an important source of livelihood, environmental services, and economic growth. In November of 2005 the Government of Kenya (GOK) ratified a new Forests Act. The act contains many innovative provisions to correct previous shortcomings, including a strong emphasis on partnerships, the engagement of local communities, and promotion of private investment. The purpose of the...

Nuclear liability and the Price--Anderson Act

International Nuclear Information System (INIS)

Wilson, R.

1977-01-01

The Price-Anderson Act is viewed as meeting public needs in a unique and responsible way, reflecting the far-sightedness of those involved in the early development of nuclear power who saw the importance of building safety into each step of the program. An extension of the Act is advised as a first step in recognizing that many potential and real disasters (e.g., dam breaks, floods, etc.) are man-made rather than ''Acts of God''. Rather than abolish the Price-Anderson Act because it is unique, the case is made for extending it to cover these other situations. Provisions of the Act are examined in terms of the role of negligence in nuclear accidents, and the conclusion is reached that public concern for reactor safety should not be affected. Limited assets on the part of insurers and insurance pools have made government involvement important but not a real subsidy because of high premiums. Premiums in the new amendment are paid retroactively when there is an accident, which relieves the problem of anticipating what premiums may be needed in the future. This limits government liability and, combined with the waiver of defenses against liability, offers better protection for the public. Recommendations for allowing tort law to operate above the $560 million Price-Anderson limits are criticized, and a counter proposal is made for reassessing the figure at an appropriate limit and extending insurance to competitive industries

76 FR 28213 - Reorganization of Foreign-Trade Zone 51 Under Alternative Site Framework; Duluth, MN

Science.gov (United States)

2011-05-16

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1758] Reorganization of Foreign-Trade Zone 51 Under Alternative Site Framework; Duluth, MN Pursuant to its authority under the Foreign-Trade... Foreign-Trade Zone 51, submitted an application to the Board (FTZ Docket 58-2010, filed 10/1/2010, amended...

77 FR 44582 - Reorganization of Foreign-Trade Zone 183 Under Alternative Site Framework; Austin, TX

Science.gov (United States)

2012-07-30

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1843] Reorganization of Foreign-Trade Zone 183 Under Alternative Site Framework; Austin, TX Pursuant to its authority under the Foreign-Trade... Austin Customs and Border Protection port of entry, and FTZ 183's existing Sites 1 through 24 would be...

Reorganization of the 3D matrix of polyelectrolytes complexes of chitosan/chondroitin sulfate swollen in different conditions of pH and immersion time

International Nuclear Information System (INIS)

Fajardo, Andre R.; Piai, Juliana F.; Rubira, Adley F.; Muniz, Edvani C.

2009-01-01

The chitosan (CT), a polysaccharide that has excellent properties for use as biomaterials, shows cationic nature and properties of high charge density in acidic solutions, thus CT can form complex polyelectrolyte (PEC) with polyanionic moieties such as the chondroitin sulfate (CS), a key component of cartilage matrix. We studied the reorganization of chains on 3D matrix of CT/CS PEC at swollen state in different conditions of pH and immersion time. It was verified that this PEC (QT/CS) has the capacity to reorganize its 3D matrix but it depends of the pH of the medium in which it is swelled and the time that remains immersed. The reorganization of the 3D matrix is caused by the reordering of the chains forming the PEC after the release of the CS, that occurs mainly at pH values higher than or close to the pKa of CT (pKa CT) . Such reorganization was detected by X-ray diffraction profiles and allows an increase in crystallinity, thermal stability and pore size of the PEC. This shows that the PEC produced can be processed to suit its use as bio material, applied i.e. as drugs release devices. (author)

Reorganization of the 3D matrix of polyelectrolytes complexes of chitosan/chondroitin sulfate swollen in different conditions of pH and immersion time

Energy Technology Data Exchange (ETDEWEB)

Fajardo, Andre R.; Piai, Juliana F.; Rubira, Adley F.; Muniz, Edvani C., E-mail: ecmuniz@uem.b [Universidade Estadual de Maringa (DG/UEM), PR (Brazil). Dept. de Quimica. Grupo de Materiais Polimericos e Compositos

2009-07-01

The chitosan (CT), a polysaccharide that has excellent properties for use as biomaterials, shows cationic nature and properties of high charge density in acidic solutions, thus CT can form complex polyelectrolyte (PEC) with polyanionic moieties such as the chondroitin sulfate (CS), a key component of cartilage matrix. We studied the reorganization of chains on 3D matrix of CT/CS PEC at swollen state in different conditions of pH and immersion time. It was verified that this PEC (QT/CS) has the capacity to reorganize its 3D matrix but it depends of the pH of the medium in which it is swelled and the time that remains immersed. The reorganization of the 3D matrix is caused by the reordering of the chains forming the PEC after the release of the CS, that occurs mainly at pH values higher than or close to the pKa of CT (pKa CT) . Such reorganization was detected by X-ray diffraction profiles and allows an increase in crystallinity, thermal stability and pore size of the PEC. This shows that the PEC produced can be processed to suit its use as bio material, applied i.e. as drugs release devices. (author)

Governing sexual behaviour through humanitarian codes of conduct.

Science.gov (United States)

Matti, Stephanie

2015-10-01

Since 2001, there has been a growing consensus that sexual exploitation and abuse of intended beneficiaries by humanitarian workers is a real and widespread problem that requires governance. Codes of conduct have been promoted as a key mechanism for governing the sexual behaviour of humanitarian workers and, ultimately, preventing sexual exploitation and abuse (PSEA). This article presents a systematic study of PSEA codes of conduct adopted by humanitarian non-governmental organisations (NGOs) and how they govern the sexual behaviour of humanitarian workers. It draws on Foucault's analytics of governance and speech act theory to examine the findings of a survey of references to codes of conduct made on the websites of 100 humanitarian NGOs, and to analyse some features of the organisation-specific PSEA codes identified. © 2015 The Author(s). Disasters © Overseas Development Institute, 2015.

Temporal evolution of brain reorganization under cross-modal training: insights into the functional architecture of encoding and retrieval networks

Science.gov (United States)

Likova, Lora T.

2015-03-01

This study is based on the recent discovery of massive and well-structured cross-modal memory activation generated in the primary visual cortex (V1) of totally blind people as a result of novel training in drawing without any vision (Likova, 2012). This unexpected functional reorganization of primary visual cortex was obtained after undergoing only a week of training by the novel Cognitive-Kinesthetic Method, and was consistent across pilot groups of different categories of visual deprivation: congenitally blind, late-onset blind and blindfolded (Likova, 2014). These findings led us to implicate V1 as the implementation of the theoretical visuo-spatial 'sketchpad' for working memory in the human brain. Since neither the source nor the subsequent 'recipient' of this non-visual memory information in V1 is known, these results raise a number of important questions about the underlying functional organization of the respective encoding and retrieval networks in the brain. To address these questions, an individual totally blind from birth was given a week of Cognitive-Kinesthetic training, accompanied by functional magnetic resonance imaging (fMRI) both before and just after training, and again after a two-month consolidation period. The results revealed a remarkable temporal sequence of training-based response reorganization in both the hippocampal complex and the temporal-lobe object processing hierarchy over the prolonged consolidation period. In particular, a pattern of profound learning-based transformations in the hippocampus was strongly reflected in V1, with the retrieval function showing massive growth as result of the Cognitive-Kinesthetic memory training and consolidation, while the initially strong hippocampal response during tactile exploration and encoding became non-existent. Furthermore, after training, an alternating patch structure in the form of a cascade of discrete ventral regions underwent radical transformations to reach complete functional

77 FR 63289 - Foreign-Trade Zone 32-Miami, Florida; Application for Reorganization Under Alternative Site...

Science.gov (United States)

2012-10-16

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-51-2012] Foreign-Trade Zone 32--Miami, Florida... submitted to the Foreign-Trade Zones Board (the Board) by the Greater Miami Foreign-Trade Zone, Inc., grantee of FTZ 32, to amend its application to reorganize FTZ 32 zone under the alternative site framework...

What is new in the Act on Nuclear Safety

International Nuclear Information System (INIS)

Novosel, N.

2005-01-01

The Act on Nuclear Safety was passed by the Croatian Parliament on 15 October 2003, and published in Narodne novine (official journal) No. 173/03. This Act regulates safety measures for using nuclear materials and equipment, regulates nuclear activities, and establishes the National Office for Nuclear Safety. The new act supersedes the Act on Protective Measures Against Ionising Radiation and Safety in the Use of Nuclear Facilities and Installations (Narodne novine No. 18/81) and the Act on Protection against Ionising Radiation and Special Safety Measures in Using Nuclear Energy (Narodne novine No. 53/91). Regulations based on the latter Act shall apply until they are replaced by new regulations based on the Act on Nuclear Safety. Provisions of this Act apply for nuclear activities, nuclear materials and specified equipment. Croatia does not have nuclear facilities on its territory, but a Croatian power utility company owns 50% of the Nuclear Power Plant Krsko on the territory of Slovenia. In that respect, Croatia has assumed responsibilities defined by the Agreement between the Government of the Republic of Slovenia and the Government of the Republic of Croatia on the Regulation of the Status and Other Legal Relationships, Connected with Investments in the Krsko Nuclear Power Plant, its Exploitation and Decommissioning (Narodne novine No. 9/02, International Agreements). Having accessioned international conventions and agreements, Croatia has also assumed the responsibility to implement their provisions. In the process of European and international integrations, Croatia has to harmonize with the European and international standards in nuclear safety.(author)

Active offer of health services in French in Ontario: Analysis of reorganization and management strategies of health care organizations.

Science.gov (United States)

Farmanova, Elina; Bonneville, Luc; Bouchard, Louise

2018-01-01

The availability of health services in French is not only weak but also inexistent in some regions in Canada. As a result, estimated 78% of more than a million of Francophones living in a minority situation in Canada experience difficulties accessing health care in French. To promote the delivery of health services in French, publicly funded organizations are encouraged to take measures to ensure that French-language services are clearly visible, available, easily accessible, and equivalent to the quality of services offered in English. This study examines the reorganization and management strategies taken by health care organizations in Ontario that provide health services in French. Review and analysis of designation plans of a sample of health care organizations. Few health care organizations providing services in French have concrete strategies to guarantee availability, visibility, and accessibility of French-language services. Implementation of the active offer of French-language services is likely to be difficult and slow. The Ontario government must strengthen collaboration with health care organizations, Francophone communities, and other key actors participating in the designation process to help health care organizations build capacities for the effective offer of French-language services. Copyright © 2017 John Wiley & Sons, Ltd.

Probing the electronic structure of redox species and direct determination of intrinsic reorganization energies of electron transfer reactions

International Nuclear Information System (INIS)

Wang, Xue-Bin; Wang, Lai-Sheng

2000-01-01

An experimental technique capable of directly determining the intrinsic reorganization energies of bimolecular electron transfer reactions is described. Appropriate solution phase redox species are prepared in the gas phase using electrospray ionization and probed using photodetachment spectroscopy. Five metal complex anions involved in the Fe 2+ -Fe 3+ redox couple are investigated and the intramolecular reorganization energies are measured directly from spectral features due to removing the most loosely bound 3d electron from the Fe(II)-complexes. The photodetachment spectra also yield electronic structure information about the Fe 2+ -Fe 3+ redox couple and provide a common electronic structure origin for the reducing capability of the Fe(II)-complexes, the most common redox reagents. (c) 2000 American Institute of Physics

78 FR 62362 - Revisions to Procedural Regulations Governing Transportation by Intrastate Pipelines; Electronic...

Science.gov (United States)

2013-10-21

...] Revisions to Procedural Regulations Governing Transportation by Intrastate Pipelines; Electronic Tariff... under the Commission's jurisdiction pursuant to the Natural Gas Policy Act of 1978 or the Natural Gas Act.\\1\\ Take notice that, effective November 12, 2013, the list of available eTariff Type of Filing...

Healh and Safety at Work etc. Act 1974

International Nuclear Information System (INIS)

1974-01-01

The main purpose of this Act is to provide a single comprehensive and integrated system of law dealing with the health, safety and welfare of workpeople, and the health and safety of the public as affected by work activities. The Act establishes a Health and Safety Commission and a Health and Safety Executive to be generally responsible for administering health and safety legislation, including those provisions of the Nuclear Installations Act 1965 governing the licensing of nuclear installations, a function which was exercised by the Secretary of State for Energy and the Secretary of State for Scotland. The provisions of the Nuclear Installations Act 1965 and 1969 which give effect to the Paris Convention and the Brussels Supplementary Convention are not affected by the Act. (NEA) [fr

Large extents of intensive land use limit community reorganization during climate warming.

Science.gov (United States)

Oliver, Tom H; Gillings, Simon; Pearce-Higgins, James W; Brereton, Tom; Crick, Humphrey Q P; Duffield, Simon J; Morecroft, Michael D; Roy, David B

2017-06-01

Climate change is increasingly altering the composition of ecological communities, in combination with other environmental pressures such as high-intensity land use. Pressures are expected to interact in their effects, but the extent to which intensive human land use constrains community responses to climate change is currently unclear. A generic indicator of climate change impact, the community temperature index (CTI), has previously been used to suggest that both bird and butterflies are successfully 'tracking' climate change. Here, we assessed community changes at over 600 English bird or butterfly monitoring sites over three decades and tested how the surrounding land has influenced these changes. We partitioned community changes into warm- and cold-associated assemblages and found that English bird communities have not reorganized successfully in response to climate change. CTI increases for birds are primarily attributable to the loss of cold-associated species, whilst for butterflies, warm-associated species have tended to increase. Importantly, the area of intensively managed land use around monitoring sites appears to influence these community changes, with large extents of intensively managed land limiting 'adaptive' community reorganization in response to climate change. Specifically, high-intensity land use appears to exacerbate declines in cold-adapted bird and butterfly species, and prevent increases in warm-associated birds. This has broad implications for managing landscapes to promote climate change adaptation. © 2017 John Wiley & Sons Ltd.

12 CFR 407.7 - Relationship to Freedom of Information Act.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Relationship to Freedom of Information Act. 407.7 Section 407.7 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES REGULATIONS GOVERNING PUBLIC OBSERVATION OF EX-IM BANK MEETINGS § 407.7 Relationship to Freedom of Information Act. Nothing in...

77 FR 56628 - Privacy Act of 1974; System of Records

Science.gov (United States)

2012-09-13

.../Central Security Service (NSA/CSS), Freedom of Information Act and Privacy Act Office, 9800 Savage Road... Agencies of Government who wrote to NSA on behalf of the constituent and who use it to respond to the.... The DoD Blanket Routine Uses published at the beginning of the NSA/ CSS's compilation of record...

Noise Trauma-Induced Behavioral Gap Detection Deficits Correlate with Reorganization of Excitatory and Inhibitory Local Circuits in the Inferior Colliculus and Are Prevented by Acoustic Enrichment.

Science.gov (United States)

Sturm, Joshua J; Zhang-Hooks, Ying-Xin; Roos, Hannah; Nguyen, Tuan; Kandler, Karl

2017-06-28

Hearing loss leads to a host of cellular and synaptic changes in auditory brain areas that are thought to give rise to auditory perception deficits such as temporal processing impairments, hyperacusis, and tinnitus. However, little is known about possible changes in synaptic circuit connectivity that may underlie these hearing deficits. Here, we show that mild hearing loss as a result of brief noise exposure leads to a pronounced reorganization of local excitatory and inhibitory circuits in the mouse inferior colliculus. The exact nature of these reorganizations correlated with the presence or absence of the animals' impairments in detecting brief sound gaps, a commonly used behavioral sign for tinnitus in animal models. Mice with gap detection deficits (GDDs) showed a shift in the balance of synaptic excitation and inhibition that was present in both glutamatergic and GABAergic neurons, whereas mice without GDDs showed stable excitation-inhibition balances. Acoustic enrichment (AE) with moderate intensity, pulsed white noise immediately after noise trauma prevented both circuit reorganization and GDDs, raising the possibility of using AE immediately after cochlear damage to prevent or alleviate the emergence of central auditory processing deficits. SIGNIFICANCE STATEMENT Noise overexposure is a major cause of central auditory processing disorders, including tinnitus, yet the changes in synaptic connectivity underlying these disorders remain poorly understood. Here, we find that brief noise overexposure leads to distinct reorganizations of excitatory and inhibitory synaptic inputs onto glutamatergic and GABAergic neurons and that the nature of these reorganizations correlates with animals' impairments in detecting brief sound gaps, which is often considered a sign of tinnitus. Acoustic enrichment immediately after noise trauma prevents circuit reorganizations and gap detection deficits, highlighting the potential for using sound therapy soon after cochlear damage

76 FR 771 - Reorganization/Expansion of Foreign-Trade Zone 14 Under Alternative Site Framework; Little Rock, AR

Science.gov (United States)

2011-01-06

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1729] Reorganization/Expansion of Foreign-Trade Zone 14 Under Alternative Site Framework; Little Rock, AR Pursuant to its authority under... the Little Rock Customs and Border [[Page 772

26 CFR 3.8 - Certain corporate reorganizations and changes in partnerships, and certain transfers on death...

Science.gov (United States)

2010-04-01

... in partnerships, and certain transfers on death. [Reserved] 3.8 Section 3.8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) CAPITAL CONSTRUCTION FUND § 3.8 Certain corporate reorganizations and changes in partnerships, and certain transfers on death...

78 FR 24154 - Notice of Availability of a National Animal Health Laboratory Network Reorganization Concept Paper

Science.gov (United States)

2013-04-24

...] Notice of Availability of a National Animal Health Laboratory Network Reorganization Concept Paper AGENCY... available a concept paper that describes a revised structure for the National Animal Health Laboratory... biological threats to the nation's food animals. The concept paper we are making available for comment...

75 FR 53637 - Foreign-Trade Zone 104-Savannah, GA; Application for Reorganization Under Alternative Site Framework

Science.gov (United States)

2010-09-01

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 51-2010] Foreign-Trade Zone 104--Savannah... to the Foreign-Trade Zones (FTZ) Board (the Board) by the Savannah Airport Commission, grantee of FTZ 104, requesting authority to reorganize the zone under the alternative site [[Page 53638

Cultural management and government role

Directory of Open Access Journals (Sweden)

Edalat Nemati

2012-08-01

Full Text Available Culture plays an important role on human lives and it has been in four ancient civilizations of China, Iran, Egypt and Greece. The civilization achievements are normally categorized in two different groups of material and immaterial. Practical experience of the material, social objective is called as a civilization and the mental aspect of spiritual experiences, spiritual and personal is called culture. The purpose of this research is to find a framework for cross-cultural management. First, we define the cultural planning and we review the existing cultural examples in Iranian society and try to provide an overall analysis. The paper also investigates the role of government on creating adaptive culture within the society and explains that government must act as leadership in creating value added culture.

78 FR 21981 - Sunshine Act Meeting

Science.gov (United States)

2013-04-12

... transparency, liquidity, efficiency, or other aspects of the structure of the corporate bond and asset-backed... provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... focus on the characteristics of the corporate bond and asset-backed securities markets today, how those...

78 FR 62364 - Sunshine Act Meeting

Science.gov (United States)

2013-10-21

... names of two offshore companies he controlled (the ``Corporate Accounts''). The law judge ordered Pierce... provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... initial decision of an administrative law judge. The law judge found that China-Biotics, Inc., an issuer...

75 FR 55382 - Sunshine Act Meetings

Science.gov (United States)

2010-09-10

... of Public Affairs at (202) 418-5080 or the SEC's office of Public Affairs at (202) 551-4120. Dated... provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange Commission (``SEC'') and the Commodity Futures Trading Commission (``CFTC'') will hold public roundtable...

'Good Governance' dan 'Governability'

Directory of Open Access Journals (Sweden)

- Pratikno

2005-03-01

Full Text Available The article endeavors to trace the outset of governance concept, its dominant meanings and discourse, and its implication towards governability. The central role of government in the governing processes has predominantly been adopted. The concept of governance was emerged precisely in the context of the failure of government as key player in regulation, economic redistribution and political participation. Governance is therefore aimed to emphasize pattern of governing which are based both on democratic mechanism and sound development management. However, practices of such good governance concept –which are mainly adopted and promoted by donor states and agencies– tend to degrade state and/or government authority and legitimacy. Traditional function of the state as sole facilitator of equal societal, political and legal membership among citizens has been diminished. The logic of fair competition has been substituted almost completely by the logic of free competition in nearly all sectors of public life. The concept and practices of good governance have resulted in decayed state authority and failed state which in turn created a condition for "ungovernability". By promoting democratic and humane governance, the article accordingly encourages discourse to reinstall and bring the idea of accountable state back in.

CORPORATE GOVERNANCE IN INDIA: AN ANALYSIS

Directory of Open Access Journals (Sweden)

Meghna Thapar

2017-03-01

Full Text Available Corporate governance is a process, relation and mechanism set up for the corporations and firms based on certain guidelines and principles by which a company is controlled and directed. The principles provided in the system ensure that the company is governed in a way that it is able to set and achieve its goals and objectives in the context of the social, regulatory and market environment, and is able to maximize profits and also benefit those whose interest is involved in it, in the long run. The division and distribution of rights and responsibilities among different participants in the corporation (such as the board of directors, managers, shareholders, creditors, auditors, regulators, and other stakeholders and inclusion of the rules and procedures for making decisions in corporate affairs are identified with the help of Corporate Governance mechanism and guidelines. The need to make corporate governance in India transparent was felt after the high profile corporate governance failure scams like the stock market scam, the UTI scam, Ketan Parikh scam, Satyam scam, which were severely criticized by the shareholders. Thus, Corporate Governance is not just company administration but more than that and includes monitoring the actions, policies, practices, and decisions of corporations, their agents, and affected stakeholders thereby ensuring fair, efficient and transparent functioning of the corporate management system. By this paper, the authors intend to examine the concept of corporate governance in India with regard to the provisions of corporate governance under the Companies Act 2013. The paper will highlight the importance and need of corporate governance in India. We will also discuss the important case laws which contributed immensely in the emergence of corporate governance in India.

78 FR 27953 - Reorganization of Foreign-Trade Zone 147 Under Alternative Site Framework Reading, Pennsylvania

Science.gov (United States)

2013-05-13

... terminate authority for Sites 20-22 if no foreign-status merchandise is admitted for a bona fide customs... Zone 147 Under Alternative Site Framework Reading, Pennsylvania Pursuant to its authority under the... application to the Board (FTZ Docket B-79-2012, docketed 11-1-2012) for authority to reorganize under the ASF...

The Role of the Chair of the School Governing Body in England

Science.gov (United States)

James, Chris; Jones, Jeff; Connolly, Michael; Brammer, Steve; Fertig, Mike; James, Jane

2012-01-01

The research reported here analysed the role of the chair of the school governing body in England, drawing on a national survey of governors and the study of governing in 30 schools. The role encompassed: being a governor; appointing and working with the head teacher; acting as a change agent; active participation in the school; organising the…

Nuclear Non-Proliferation Policy Act of 1977. Hearings before the Subcommittee on Energy Research and Development of the Committee on Energy and Natural Resources, United States Senate, Ninety-Fifth Congress, First Session, June 10, September 13, 14, 1977

International Nuclear Information System (INIS)

Anon.

1978-01-01

Senator Frank Church presented the opening statement on the June 10, 1977 hearing concerning the Nuclear Non-Proliferation Policy Act of 1977, S.1432. S.1432 is designed to establish a nonproliferation framework with specific objectives established for the ERDA nuclear energy programs. The ERDA authorization bill is the budgetary vehicle to implement these objectives. The Committee on Energy and Natural Resources obtained joint referral of certain portions of the Nuclear Non-Proliferation Act to insure that nonproliferation policy is implemented in a manner consistent with the policy of having sufficent energy for this country and foreign countries in the future. Additionally, the Subcommittee on Energy Research and Development must examine the cost and the consequences of various initiatives before they are implemented. For example, the proposal to guarantee uranium enrichment services for foreign nations poses specific requirements on ERDA to expand considerably our enrichment capacity by the year 2000. Without reprocessing, it is expected that spent fuel rods from abroad will be returned to this country for storage with attendant costs and siting decisions. Also, international fuel cycle evaluation programs must be carefully examined to insure that all options, including regional fuel cycle centers with international controls and inspection, are considered in seeking international approaches to the nonproliferation objectives. It is these and related questions to which the subcommittee seeks answers. The hearings on September 13 and 14 focused on S.897, a bill to strengthen U.S. policies on nonproliferation and to reorganize certain export functions of the Federal government to promote more efficient administration of such functions. Statements were presented by experts in government, private firms, and industrial sectors

Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling

Energy Technology Data Exchange (ETDEWEB)

Jackson, Shawn S. [McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, 6159 Wisconsin Institute for Medical Research, 1111 Highland Avenue, Madison, WI 53705 (United States); Medical Scientist Training Program, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705 (United States); Cellular and Molecular Biology Program, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705 (United States); Oberley, Christopher [McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, 6159 Wisconsin Institute for Medical Research, 1111 Highland Avenue, Madison, WI 53705 (United States); Hooper, Christopher P. [McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, 6159 Wisconsin Institute for Medical Research, 1111 Highland Avenue, Madison, WI 53705 (United States); Cellular and Molecular Biology Program, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705 (United States); Grindle, Kreg [Department of Medicine, Division of Hematology and Oncology, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705 (United States); Wuerzberger-Davis, Shelly [McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, 6159 Wisconsin Institute for Medical Research, 1111 Highland Avenue, Madison, WI 53705 (United States); Wolff, Jared [Department of Medicine, Division of Hematology and Oncology, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705 (United States); and others

2015-02-01

The NF-κB family of transcription factors regulates numerous cellular processes, including cell proliferation and survival responses. The constitutive activation of NF-κB has also emerged as an important oncogenic driver in many malignancies, such as activated B-cell like diffuse large B cell lymphoma, among others. In this study, we investigated the impact and mechanisms of action of Withaferin A, a naturally produced steroidal lactone, against both signal-inducible as well as constitutive NF-κB activities. We found that Withaferin A is a robust inhibitor of canonical and constitutive NF-κB activities, leading to apoptosis of certain lymphoma lines. In the canonical pathway induced by TNF, Withaferin A did not disrupt RIP1 polyubiquitination or NEMO–IKKβ interaction and was a poor direct IKKβ inhibitor, but prevented the formation of TNF-induced NEMO foci which colocalized with TNF ligand. While GFP-NEMO efficiently formed TNF-induced foci, a GFP-NEMO{sup Y308S} mutant that is defective in binding to polyubiquitin chains did not form foci. Our study reveals that Withaferin A is a novel type of IKK inhibitor which acts by disrupting NEMO reorganization into ubiquitin-based signaling structures in vivo. - Highlights: • Withaferin A, a NF-κB inhibitor, disrupts signaling induced NEMO localization, a novel point of inhibition. • NEMO can be localized to distinct signaling foci after treatment with TNF. • ABC-type DLCBL cells can be sensitized to apoptosis after treatment with Withaferin A.

Budget Monitoring and Control in South African Township Schools: Democratic Governance at Risk

Science.gov (United States)

Mestry, Raj; Naidoo, Gans

2009-01-01

This article investigates budget monitoring and control in township schools in South Africa. The enactment of the Schools Act 1996 revolutionized school financial management in South Africa, making it part of the drive for democratic school governance. School governing bodies had to be established, whose responsibility it became to manage finances…

Government technology push in agribusiness: a model of endogenous growth

Directory of Open Access Journals (Sweden)

Francisco Venegas Martínez

2008-10-01

Full Text Available This paper develops a model of endogenous growth where the government acts as a promoting agent to boost technology in agribusiness. In the framework of a monetary economy, the optimal level of government spending to enhance technology in the agricultural industry is characterized. Moreover the impact of such a spending on economic welfare is assessed. Finally, a number of agro-oriented policies to increase growth in the sector are established.

Structural reorganization of the early visual cortex following Braille training in sighted adults.

Science.gov (United States)

Bola, Łukasz; Siuda-Krzywicka, Katarzyna; Paplińska, Małgorzata; Sumera, Ewa; Zimmermann, Maria; Jednoróg, Katarzyna; Marchewka, Artur; Szwed, Marcin

2017-12-12

Training can induce cross-modal plasticity in the human cortex. A well-known example of this phenomenon is the recruitment of visual areas for tactile and auditory processing. It remains unclear to what extent such plasticity is associated with changes in anatomy. Here we enrolled 29 sighted adults into a nine-month tactile Braille-reading training, and used voxel-based morphometry and diffusion tensor imaging to describe the resulting anatomical changes. In addition, we collected resting-state fMRI data to relate these changes to functional connectivity between visual and somatosensory-motor cortices. Following Braille-training, we observed substantial grey and white matter reorganization in the anterior part of early visual cortex (peripheral visual field). Moreover, relative to its posterior, foveal part, the peripheral representation of early visual cortex had stronger functional connections to somatosensory and motor cortices even before the onset of training. Previous studies show that the early visual cortex can be functionally recruited for tactile discrimination, including recognition of Braille characters. Our results demonstrate that reorganization in this region induced by tactile training can also be anatomical. This change most likely reflects a strengthening of existing connectivity between the peripheral visual cortex and somatosensory cortices, which suggests a putative mechanism for cross-modal recruitment of visual areas.

Atrophy and Primary Somatosensory Cortical Reorganization after Unilateral Thoracic Spinal Cord Injury: A Longitudinal Functional Magnetic Resonance Imaging Study

Directory of Open Access Journals (Sweden)

Jia-Sheng Rao

2013-01-01

Full Text Available The effects of traumatic spinal cord injury (SCI on the changes in the central nervous system (CNS over time may depend on the dynamic interaction between the structural integrity of the spinal cord and the capacity of the brain plasticity. Functional magnetic resonance imaging (fMRI was used in a longitudinal study on five rhesus monkeys to observe cerebral activation during upper limb somatosensory tasks in healthy animals and after unilateral thoracic SCI. The changes in the spinal cord diameters were measured, and the correlations among time after the lesion, structural changes in the spinal cord, and primary somatosensory cortex (S1 reorganization were also determined. After SCI, activation of the upper limb in S1 shifted to the region which generally dominates the lower limb, and the rostral spinal cord transverse diameter adjacent to the lesion exhibited obvious atrophy, which reflects the SCI-induced changes in the CNS. A significant correlation was found among the time after the lesion, the spinal cord atrophy, and the degree of contralateral S1 reorganization. The results indicate the structural changes in the spinal cord and the dynamic reorganization of the cerebral activation following early SCI stage, which may help to further understand the neural plasticity in the CNS.

Annual report to Congress on Federal Government energy management and conservation programs, Fiscal year 1994

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-10-06

This report provides sinformation on energy consumption in Federal buildings and operations and documents activities conducted by Federal agencies to meet statutory requirements of the National Energy Conservation Policy Act. It also describes energy conservation and management activities of the Federal Government under section 381 of the Energy Policy and Conservation Act. Implementation activities undertaken during FY94 by the Federal agencies under the Energy Policy Act of 1992 and Executive Orders 12759 and 12902 are also described. During FY94, total (gross) energy consumption of the US Government, including energy consued to produce, process, and transport energy, was 1.72 quadrillion Btu. This represents {similar_to}2.0% of the total 85.34 quads used in US.

75 FR 28568 - Reorganization of Foreign-Trade Zone 2, under Alternative Site Framework, New Orleans, Louisiana...

Science.gov (United States)

2010-05-21

... Zone 2, under Alternative Site Framework, New Orleans, Louisiana, Area Pursuant to its authority under... St. Bernard Parishes, Louisiana, adjacent to the New Orleans Customs and Border Protection port of... establishment or reorganization of general-purpose zones; Whereas, the Board of Commissioners of the Port of New...

77 FR 8804 - Foreign-Trade Zone 202-Los Angeles, CA; Application for Reorganization and Expansion Under...

Science.gov (United States)

2012-02-15

... establishment or reorganization of general-purpose zones and can permit significantly greater flexibility in the...)--201 W. Carob Street, Compton (sunset 12/31/2013); Site 19 (18.5 acres)--Young's Market Company, 6711... findings and recommendations to the Board. Public comment is invited from interested parties. Submissions...

76 FR 22938 - Sunshine Act Meetings

Science.gov (United States)

2011-04-25

... of Public Affairs at (202) 418-5080 or the SEC's office of Public Affairs at (202) 551-4120. Dated... provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange Commission (``SEC'') and the Commodity Futures Trading Commission (``CFTC'') will hold a public roundtable to...

Long-term reorganization of structural brain networks in a rabbit model of intrauterine growth restriction.

Science.gov (United States)

Batalle, Dafnis; Muñoz-Moreno, Emma; Arbat-Plana, Ariadna; Illa, Miriam; Figueras, Francesc; Eixarch, Elisenda; Gratacos, Eduard

2014-10-15

Characterization of brain changes produced by intrauterine growth restriction (IUGR) is among the main challenges of modern fetal medicine and pediatrics. This condition affects 5-10% of all pregnancies and is associated with a wide range of neurodevelopmental disorders. Better understanding of the brain reorganization produced by IUGR opens a window of opportunity to find potential imaging biomarkers in order to identify the infants with a high risk of having neurodevelopmental problems and apply therapies to improve their outcomes. Structural brain networks obtained from diffusion magnetic resonance imaging (MRI) is a promising tool to study brain reorganization and to be used as a biomarker of neurodevelopmental alterations. In the present study this technique is applied to a rabbit animal model of IUGR, which presents some advantages including a controlled environment and the possibility to obtain high quality MRI with long acquisition times. Using a Q-Ball diffusion model, and a previously published rabbit brain MRI atlas, structural brain networks of 15 IUGR and 14 control rabbits at 70 days of age (equivalent to pre-adolescence human age) were obtained. The analysis of graph theory features showed a decreased network infrastructure (degree and binary global efficiency) associated with IUGR condition and a set of generalized fractional anisotropy (GFA) weighted measures associated with abnormal neurobehavior. Interestingly, when assessing the brain network organization independently of network infrastructure by means of normalized networks, IUGR showed increased global and local efficiencies. We hypothesize that this effect could reflect a compensatory response to reduced infrastructure in IUGR. These results present new evidence on the long-term persistence of the brain reorganization produced by IUGR that could underlie behavioral and developmental alterations previously described. The described changes in network organization have the potential to be used

Equal Remuneration (Amendment) Act, 1987 (No. 49 of 1987), 16 December 1987.

Science.gov (United States)

1987-01-01

This Act amends the Equal Remuneration Act, 1976, specifically to prohibit discrimination between men and women in relation to conditions of service subsequent to employment such as promotions, training, or transfer. The original Act contained no such provisions. Sections of the Act are also amended to provide for greater penalties and for the lodging of complaints by any person aggrieved and by any recognized welfare institution or organization, in addition to government officials. full text

Photoelectron spectroscopy on the charge reorganization energy and small polaron binding energy of molecular film

Energy Technology Data Exchange (ETDEWEB)

Kera, Satoshi, E-mail: kera@ims.ac.jp [Institute for Molecular Science, Myodaiji, Okazaki 444-8585 (Japan); Department of Nanomaterial Science, Graduate School of Advanced Integration Science, Chiba University, Inage-ku, Chiba 263-8522 (Japan); Ueno, Nobuo [Department of Nanomaterial Science, Graduate School of Advanced Integration Science, Chiba University, Inage-ku, Chiba 263-8522 (Japan)

2015-10-01

Understanding of electron-phonon coupling as well as intermolecular interaction is required to discuss the mobility of charge carrier in functional molecular solids. This article summarizes recent progress in direct measurements of valence hole-vibration coupling in ultrathin films of organic semiconductors by using ultraviolet photoelectron spectroscopy (UPS). The experimental study of hole-vibration coupling of the highest occupied molecular orbital (HOMO) state in ordered monolayer film by UPS is essential to comprehend hole-hopping transport and small-polaron related transport in organic semiconductors. Only careful measurements can attain the high-resolution spectra and provide key parameters in hole-transport dynamics, namely the charge reorganization energy and small polaron binding energy. Analyses methods of the UPS HOMO fine feature and resulting charge reorganization energy and small polaron binding energy are described for pentacene and perfluoropentacene films. Difference between thin-film and gas-phase results is discussed by using newly measured high-quality gas-phase spectra of pentacene. Methodology for achieving high-resolution UPS measurements for molecular films is also described.

76 FR 12645 - Ownership Limitations and Governance Requirements for Security-Based Swap Clearing Agencies...

Science.gov (United States)

2011-03-08

... 3235-AK74 Ownership Limitations and Governance Requirements for Security- Based Swap Clearing Agencies... the Dodd-Frank Act, the Commission shall adopt such rules if it determines that they are necessary or appropriate to improve the governance of, or to mitigate systemic risk, promote competition or mitigate...

Framework for local government to implement integrated water ...

African Journals Online (AJOL)

The Water Services Act (No. 8 of 1997) of South Africa states that water service delivery is the responsibility of local government as Water Services Authorities. The principal legal responsibility is to complete a Water Services Development Plan (WSDP) every 5 years with annual review. The WSDP encapsulates all the ...

The National Biological Information Infrastructure as an E-Government tool

Science.gov (United States)

Sepic, R.; Kase, K.

2002-01-01

Coordinated by the U.S. Geological Survey (USGS), the National Biological Information Infrastructure (NBII) is a Web-based system that provides access to data and information on the nation's biological resources. Although it was begun in 1993, predating any formal E-Government initiative, the NBII typifies the E-Government concepts outlined in the President's Management Agenda, as well as in the proposed E-Government Act of 2002. This article-an individual case study and not a broad survey with extensive references to the literature-explores the structure and operation of the NBII in relation to several emerging trends in E-Government: end-user focus, defined and scalable milestones, public-private partnerships, alliances with stakeholders, and interagency cooperation. ?? 2002 Elsevier Science Inc. All rights reserved.

77 FR 43048 - Foreign-Trade Zone 32-Miami, FL; Application for Reorganization Under Alternative Site Framework

Science.gov (United States)

2012-07-23

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-51-2012] Foreign-Trade Zone 32--Miami, FL... Foreign-Trade Zones (FTZ) Board (the Board) by the Greater Miami Foreign-Trade Zone, Inc., grantee of FTZ 32, requesting authority to reorganize the zone under the alternative site framework (ASF) adopted by...

Reorganization of Functional Brain Maps After Exercise Training: Importance of Cerebellar-Thalamic-Cortical Pathway

OpenAIRE

Holschneider, DP; Yang, J; Guo, Y; Maarek, J-M I

2007-01-01

Exercise training (ET) causes functional and morphologic changes in normal and injured brain. While studies have examined effects of short-term (same day) training on functional brain activation, less work has evaluated effects of long-term training, in particular treadmill running. An improved understanding is relevant as changes in neural reorganization typically require days to weeks, and treadmill training is a component of many neurorehabilitation programs.

Nigeria's national health act 2014: a review of some of its ...

African Journals Online (AJOL)

Nigeria's National Health Act 2014 was enacted on the 31st of October, 2014. The Act which provides a legal framework for the regulation and management of Nigeria's national health system, bristles with implications such as the need for improved political commitment by government to the health of Nigerians, improved ...

48 CFR 252.209-7001 - Disclosure of ownership or control by the government of a terrorist country.

Science.gov (United States)

2010-10-01

...) (a) Definitions. As used in this provision— (1) Government of a terrorist country includes the state... the government of which has repeatedly provided support for acts of international terrorism. As of the...

75 FR 67433 - Waiver of Restriction on Assistance to the Government of Saudi Arabia

Science.gov (United States)

2010-11-02

... DEPARTMENT OF STATE [Public Notice: 7220] Waiver of Restriction on Assistance to the Government of Saudi Arabia Pursuant to Section 7041 of the Department of State, Foreign Operations, and Related Programs Appropriations Act, 2010 (Division F, Pub. L. 111-117) (``the Act''), I hereby determine that it...

Environmental Guidance Program Reference Book: Marine Protection, Research, and Sanctuaries Act and Marine Mammal Protection Act. Revision 3

Energy Technology Data Exchange (ETDEWEB)

1988-01-31

Two laws governing activities in the marine environment are considered in this Reference Book. The Marine Protection, Research, and Sanctuaries Act (MPRSA, P.L. 92-532) regulates ocean dumping of waste, provides for a research program on ocean dumping, and provides for the designation and regulation of marine sanctuaries. The Marine Mammal Protection Act (MMPA, P.L. 92-522) establishes a federal program to protect and manage marine mammals. The Fishery Conservation and Management Act (FCMA, P.L. 94-265) establishes a program to regulate marine fisheries resources and commercial marine fishermen. Because the Department of Energy (DOE) is not engaged in any activities that could be classified as fishing under FCMA, this Act and its regulations have no implications for the DOE; therefore, no further consideration of this Act is given within this Reference Book. The requirements of the MPRSA and the MMPA are discussed in terms of their implications for the DOE.

16 CFR 1608.6 - Reference to guaranty by Government prohibited.

Science.gov (United States)

2010-01-01

... prohibited. 1608.6 Section 1608.6 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS... guaranty by Government prohibited. No representation nor suggestion shall be made in advertising or... conforms to a flammability standard in effect under the act. ...

Cortical Reorganization in Patients Recovered from Bell’s Palsy: An Orofacial and Finger Movements Task-State fMRI Study

Directory of Open Access Journals (Sweden)

Jaeyoun Lee

2016-01-01

Full Text Available Objective. To explore cortical reorganization of patients recovered from Bell’s palsy (BP by task-state functional magnetic resonance imaging (fMRI during finger and orofacial movements and provide more evidence for acupuncture clinical treatment of BP. Methods. We collected 17 BP patients with complete clinical recovery (BP group and 20 healthy volunteers (control group accepted the task-state fMRI scans with lip pursing movements and finger movements, respectively. Results. It was found that there were significant differences of brain functional status between the two groups. Conclusions. The results showed that there was cortical reorganization in the brain of patients recovered from BP after acupuncture treatment, which also suggested the relationship between the hand motor areas and facial motor areas of BP patients.

76 FR 38357 - Reorganization of Foreign-Trade Zone 102, Under Alternative Site Framework; St. Louis, MO

Science.gov (United States)

2011-06-30

... Zone 102, Under Alternative Site Framework; St. Louis, MO Pursuant to its authority under the Foreign.../2010) as an option for the establishment or reorganization of general-purpose zones; Whereas, the St... the City of St. Louis and St. Louis County, Missouri, within and adjacent to the St. Louis Customs and...

75 FR 29727 - Reorganization of Foreign-Trade Zone 37 Under Alternative Site Framework Orange County, NY

Science.gov (United States)

2010-05-27

... Zone 37 Under Alternative Site Framework Orange County, NY Pursuant to its authority under the Foreign... reorganization of general-purpose zones; Whereas, Orange County, New York, grantee of Foreign-Trade Zone 37... under the ASF with a service area of Orange County, New York, adjacent to the New York/Newark Customs...

78 FR 27364 - Reorganization of Foreign-Trade Zone 241 Under Alternative Site Framework Fort Lauderdale, Florida

Science.gov (United States)

2013-05-10

... Zone 241 Under Alternative Site Framework Fort Lauderdale, Florida Pursuant to its authority under the...-48-2012, docketed 6/27/2012) for authority to reorganize under the ASF with a service area comprised... Everglades Customs and Border Protection port of entry, to modify Site 1 by removing acreage, to expand Sites...

39 CFR 211.4 - Interim personnel regulations.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Interim personnel regulations. 211.4 Section 211.4... under the Postal Reorganization Act. (b) Continuation of Personnel Provisions of Former title 39, U.S.C... collective bargaining agreement under the Postal Reorganization Act, all provisions of former title 39, U.S.C...

Political instability and the ability of local government to respond to reputational threats in unison

DEFF Research Database (Denmark)

Grøn, Caroline Louise Howard; Salomonsen, Heidi Houlberg

2017-01-01

This article investigates whether local governments are able to act in a unified manner when responding to reputational threats posed by negative media coverage. Based on an argument that local governments facing political instability are less able to perform in unison, the article investigates a...

Marriage and Matrimonial Property Law Amendment Act (No. 3 of 1988), 25 February 1988.

Science.gov (United States)

1988-01-01

This Act puts Black civil marriages on the same footing as those of the rest of the population of South Africa. Such marriages entered into after the commencement of the Act are automatically governed by a community property regime, rather than by separation of property, and subject to Chapters 2 and 3 of the Matrimonial Property Act (Number 88 of 1984), which increased the legal protection afforded to women in marriage. The Act also forbids a Black man and woman from marrying according to a civil ceremony, if the man is involved in a customary union with another woman. Although the Act as a whole is not retrospective in effect, it does authorize a court to direct that the assets of one spouse be made over to the other spouse on divorce when the spouses were married by civil ceremony under Section 22(6) of the Black Administration Act (No. 38 of 1927) before the commencement of this Act. Under the Act, a couple may choose by antenuptial agreement not to be governed by a community property regime, and a couple married under a separation of property regime may choose to change it. full text

The Federal Government's supervisory authority, Land jurisdiction, and the Atomic Energy Act

International Nuclear Information System (INIS)

Steinberg, R.

1990-01-01

The instructions given in spring 1988 by the Federal German Minister of the Environment to the Minister of Economics of the Land North-Rhine Westphalia, in matters concerning the Kalkar nuclear reactor, form the background of the expert opinion presented as an analysis of significant problems arising in connection with the execution of Federal laws. The development of legal criteria for issuing instructions is analysed as a point of main interest in the process. The author discusses an important requirement given by the Constitution, namely that the principle of federation-agreeable conduct involves the duty to minimize interference with the responsibilities and jurisdiction of a Land. The Land North-Rhine Westphalia presented this expert opinion in April 1989 in legal proceedings before the Federal Constitutional Court in a dispute between the Federal Government and the Lands over Art. 93, paragraph 1, no. 3 of the Constitution. The decision given by the Federal Constitutional Court on 22 May 1990 confirmed the legality of the Federal Government's conduct in this matter. (orig./HP) [de

76 FR 33019 - Waiver of Restriction on Assistance to the Royal Government of Cambodia

Science.gov (United States)

2011-06-07

... DEPARTMENT OF STATE [Public Notice: 7491] Waiver of Restriction on Assistance to the Royal Government of Cambodia Pursuant to Section 7086(c)(2) of the Department of State, Foreign Operations, and... waive the requirements of Section 7086(c)(1) of the Act with respect to the Royal Government of Cambodia...

75 FR 59782 - Waiver of Restriction on Assistance to the Government of Saudi Arabia

Science.gov (United States)

2010-09-28

... DEPARTMENT OF STATE Waiver of Restriction on Assistance to the Government of Saudi Arabia Pursuant to section 7086(c)(2) of the Department of State, Foreign Operations, and Related Programs... States to waive the requirements of section 7086(c)(1) of the Act with respect to the Government of Saudi...

The effect of establishing a new, reorganized emergency department on quality of clinical healthcare and patient satisfaction

DEFF Research Database (Denmark)

Mattsson, Maria Søe

2015-01-01

in Denmark is seen. The quasi-experimental design of this study makes it difficult to conclude whether the observed improvement is directly related to the establishment of the new emergency department; however, significant results seems to be associated to the specific initiatives in the reorganization...

United People : designing a new model of global governance

NARCIS (Netherlands)

Romme, A.G.L.; Ansell, C.; Buck, J.; Choi, Y.; van der Eyden, R.; Figueroa Huencho, V.; John, E.; Kunkler, T.; Mair, J.; Meijer, A.; Meyer, R.; Stephenson, K.; Välikangas, L.; Whitestone, N.; Yu, C.

2018-01-01

Human-driven changes on this planet have been giving rise to global warming, social instability, civil wars, and acts of terrorism. The existing system of global governance is not equipped to effectively address these enormous challenges. It is slow where one must move quickly, favors bureaucracy

25 CFR Appendix A to Part 1000 - Model Compact of Self-Governance Between the Tribe and the Department of the Interior

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Model Compact of Self-Governance Between the Tribe and..., INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Pt. 1000, App. A Appendix A to Part 1000—Model...

Rapid reorganization of adult rat motor cortex somatic representation patterns after motor nerve injury.

OpenAIRE

Sanes, J N; Suner, S; Lando, J F; Donoghue, J P

1988-01-01

The potential for peripheral nerve injury to reorganize motor cortical representations was investigated in adult rats. Maps reflecting functional connections between the motor cortex and somatic musculature were generated with intracortical electrical stimulation techniques. Comparison of cortical somatotopic maps obtained in normal rats with maps generated from rats with a facial nerve lesion indicated that the forelimb and eye/eyelid representations expanded into the normal vibrissa area. R...

Spatial Reorganization of the Endoplasmic Reticulum during Mitosis Relies on Mitotic Kinase Cyclin A in the Early Drosophila Embryo

Science.gov (United States)

Bergman, Zane J.; Mclaurin, Justin D.; Eritano, Anthony S.; Johnson, Brittany M.; Sims, Amanda Q.; Riggs, Blake

2015-01-01

Mitotic cyclin-dependent kinase with their cyclin partners (cyclin:Cdks) are the master regulators of cell cycle progression responsible for regulating a host of activities during mitosis. Nuclear mitotic events, including chromosome condensation and segregation have been directly linked to Cdk activity. However, the regulation and timing of cytoplasmic mitotic events by cyclin:Cdks is poorly understood. In order to examine these mitotic cytoplasmic events, we looked at the dramatic changes in the endoplasmic reticulum (ER) during mitosis in the early Drosophila embryo. The dynamic changes of the ER can be arrested in an interphase state by inhibition of either DNA or protein synthesis. Here we show that this block can be alleviated by micro-injection of Cyclin A (CycA) in which defined mitotic ER clusters gathered at the spindle poles. Conversely, micro-injection of Cyclin B (CycB) did not affect spatial reorganization of the ER, suggesting CycA possesses the ability to initiate mitotic ER events in the cytoplasm. Additionally, RNAi-mediated simultaneous inhibition of all 3 mitotic cyclins (A, B and B3) blocked spatial reorganization of the ER. Our results suggest that mitotic ER reorganization events rely on CycA and that control and timing of nuclear and cytoplasmic events during mitosis may be defined by release of CycA from the nucleus as a consequence of breakdown of the nuclear envelope. PMID:25689737

The governance of cooperative societies under the Basque Act of 24-6.1993

Directory of Open Access Journals (Sweden)

Enrique Gadea Soler

2005-12-01

Full Text Available This paper briefly presents the general guidelines of governance of cooperatives. Because of the numerous existing laws in Spain, one looks at the provisions of the State Law and Law in Basque Contry.

The Government's Role in Facing the Injustice of Global Trade

OpenAIRE

Sood, Muhammad

2013-01-01

Despite the controversy about the liberalization of trade, however the government of Indonesia has ratified the WTO provisions by the discharge of the Act Number 7 Year 1994 concerning the Agreement on establishment of the World Trade Organization. This is a fact of law that formed base on the political will of the Indonesian government to encourage the free trade system as an impact of the circulation of the vital flow of goods, services, capital and labor among countries in both the regiona...

Hippocampal-neocortical functional reorganization underlies children's cognitive development.

Science.gov (United States)

Qin, Shaozheng; Cho, Soohyun; Chen, Tianwen; Rosenberg-Lee, Miriam; Geary, David C; Menon, Vinod

2014-09-01

The importance of the hippocampal system for rapid learning and memory is well recognized, but its contributions to a cardinal feature of children's cognitive development-the transition from procedure-based to memory-based problem-solving strategies-are unknown. Here we show that the hippocampal system is pivotal to this strategic transition. Longitudinal functional magnetic resonance imaging (fMRI) in 7-9-year-old children revealed that the transition from use of counting to memory-based retrieval parallels increased hippocampal and decreased prefrontal-parietal engagement during arithmetic problem solving. Longitudinal improvements in retrieval-strategy use were predicted by increased hippocampal-neocortical functional connectivity. Beyond childhood, retrieval-strategy use continued to improve through adolescence into adulthood and was associated with decreased activation but more stable interproblem representations in the hippocampus. Our findings provide insights into the dynamic role of the hippocampus in the maturation of memory-based problem solving and establish a critical link between hippocampal-neocortical reorganization and children's cognitive development.

76 FR 63660 - Sunshine Act Meetings; Notice

Science.gov (United States)

2011-10-13

... LEGAL SERVICES CORPORATION Sunshine Act Meetings; Notice DATES: Date And Time: The Legal Services..., the Governance & Performance Review Committee meeting will be held at the Hyatt Regency Chicago Hotel..., October 18, 2011 Time. 1. Promotion & Provision for the Delivery of Legal Services Committee. 10:15 p.m. 2...

METHODOLOGICAL ASPECTS OF RURAL DEVELOPMENT GOVERNANCE CASE STUDY

Directory of Open Access Journals (Sweden)

Vitalina TSYBULYAK

2014-01-01

Full Text Available The article discusses current approaches to the process of assessing rural development governance, reveals its advantages and disadvantages. The article as well presents performance system indicators of governance process by means of two elements of dynamics assessment, rural development (economic, financial, and social sphere, ecology and population health and management process (assessment of strategic plan (concept of development, program of socioeconomic development of rural areas, current activity of local authorities, in particular. More over, it is suggested to use typology of approaches (objective (evolutionary, command and control, economic (infrastructural, complex, and qualitative to definition of process essence of rural development governance and correlation of traditional functions, performed by the subjects of the governance process of rural development (state authorities institutions, local authorities institutions, economic entities, and community. Adjusting traditional functions, performed by governance subjects of local development, their supplementing with new ones, relevant to the present-to-date model of «shared governance» is an important element of analysis of assessment tools for effectiveness of rural development governance. In addition, the author defines functioning of two forms of rural population involvement into the process of rural development governance: active and passive. Active one suggests that rural population participate in making and implementing governance decisions (public meetings, organization of social discussions, and development of territory community self-governance; passive one suggests that the emphasis is placed only on information distribution among population (meetings with parliament members, direct phone lines with territory governors, publication of normative and legal acts and reports on budget execution

Energy Conservation of the Designated Government Buildings in Thailand

Directory of Open Access Journals (Sweden)

Wangskarn Prapat

2016-01-01

Full Text Available The designated government buildings have implemented and administered energy program under the energy development and promotion Act 2007 for many years continuously until 2015. Appointment person responsible for energy, performing energy management and implementing the energy conservation work plan and measures are legal requirements for the designated buildings. Therefore, the ministry of Energy has launched the project to support the implementation of energy management. The aim of the project was to create the energy management system in the designated government buildings, and to reduce energy consumption. In this paper, the evaluation of the project has been presented from the achievements of 839 designated government buildings. The energy saving is more than 440 ktoe/year. This is about 3% of energy consumptions of buildings.

42 CFR 137.379 - Do Davis-Bacon wage rates apply to construction projects performed by Self-Governance Tribes...

Science.gov (United States)

2010-10-01

... projects performed by Self-Governance Tribes using Federal funds? 137.379 Section 137.379 Public Health... HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Other § 137.379 Do Davis-Bacon wage rates apply to construction projects performed by Self-Governance Tribes using Federal funds? Davis-Bacon Act...

Fundamental Consumer Rights Under the Consumer Protection Act 68 of 2008: A Critical Overview and Analysis

Directory of Open Access Journals (Sweden)

R van Niekerk

2010-12-01

Full Text Available South Africa was in need of a comprehensive framework of legislation, policies and government authorities to regulate consumer-supplier interaction. The Consumer Protection Act 68 of 2008, which was signed by the President of the Republic of South Africa on 29 April 2009 and published in the Government Gazette on 29 April 2009, now provides an extensive framework for consumer protection and aims to develop, enhance and protect the rights of consumers and to eliminate unethical suppliers and improper business practices. Certain areas of the common law regarding consumer rights have been codified by the Act and certain unfair business practices that were previously unregulated are now governed by the Act. The Act has a wide field of application. It applies to every transaction occurring within South Africa for the supply of goods or services or the promotion of goods or services and the goods or services themselves, unless the transaction is exempted from the application of the Act. The Act also specifically regulates aspects of franchise agreements. In terms of the Act, consumers obtain several new rights and some existing rights are broadened and reinforced. These rights are: the right to equality in the consumer market; privacy; choice; disclosure and information; fair and responsible marketing; fair and honest dealing; fair, just and reasonable terms and conditions; and fair value, good quality and safety. The last right in terms of the Act deals with a supplier's accountability to consumers. The authors critically analyse and discuss these rights. It is clear that the Act is written in favour of the consumer.

Re-reading early modern prayer as social act

DEFF Research Database (Denmark)

Sterrett, Joseph William

2013-01-01

Literary criticism is increasingly interested in prayer as a cultural and literary mode. This article proposes a theoretical framework for reading prayer as a performance, as an act governed by community conventions with effects in the social world. Drawing upon groundbreaking work by Marcel Maus...... and Hans Georg Gadamer, and citing critical reading of Shakespeare’s King Lear, The Tempest, and Hamlet, I show how prayer can be read as an act defined by real and imagined audiences while retaining individual self expression....

Transparency and Good Governance in Spain

Directory of Open Access Journals (Sweden)

Catalina Larach

2015-06-01

Full Text Available Nowadays, transparency and Governance are relevant for Spain. Especially, for the dissatisfied citizenship and the weakness in national and local institutions over the last few years, with results like not trusting, less guarantee on healthcare and education system, the corruption in public administration, politics-economic issues, and so on. Although, in the European Union, Spain has been one of the last countries to regulate this issue, whit Act 19/2013 there are new objectives relating to open government, citizenship, technology, accountability. Moreover in relation with the structure of administration because the “commission for transparency and good governance” was initiated on last 19th January. In general, its effectiveness in moderating this issue and applying measures in order to get administration systems cleaner in countries like Spain.

Identifying Procurement Fraud in Defense Agencies: An Analysis of the Government Purchase Card Program

Science.gov (United States)

2011-04-30

fielding, contracting, interoperability, organizational behavior, risk management , cost estimating, and many others. Approaches range from... COSO ), (Whittington & Pany, 2012). In addition, the Federal Financial Management Improvement Act of 1996 identified internal control as an...fraud indicators within the DoD Government Purchase Card Programs and provides recommendations for improving the management of Government Purchase

Proposed amendments to the Accord Acts to incorporate an offshore occupational health and safety regime

Energy Technology Data Exchange (ETDEWEB)

NONE

2010-04-15

The Canada Atlantic Accords signed in 1985 with Newfoundland and Labrador and in 1986 with Nova Scotia facilitate the orderly development of petroleum resources in Canada's Atlantic offshore area. These accords established the Canada-Newfoundland and Labrador Offshore Petroleum Board and the Canada-Nova Scotia Offshore Petroleum Board and made them responsible, on behalf of the federal government and the respective provincial government, for the joint management of petroleum resources in the offshore area. While the federal and provincial governments are responsible for establishing the regime for operational safety and occupational health and safety to be administered by the 2 boards, there is no division of responsibilities between the provincial occupational health and safety regime and the Accord Acts. There is agreement amongst governments that the accord acts should be amended to clarify responsibilities and vest sole authority for occupational health and safety in the accord acts. This document outlined the policy intent of the proposed amendments to the Accord Acts to ground an occupational health and safety regime for the east coast offshore areas in legislation. The document discussed legislation to be amended; governance; and provisions of the occupational health and safety regime. General matters such as the application of the policy, allocation of responsibility and interpretation were also discussed. The general duties of the operators were identified along with specific duties of operators; duties related to transportation; occupational health and safety policy; health and safety management system; codes of practice; notification of accidents; duties of employers; and occupational health and safety program. Compliance and enforcement provisions were also summarized.

Reorganization of the Cerebro-Cerebellar Network of Language Production in Patients with Congenital Left-Hemispheric Brain Lesions

Science.gov (United States)

Lidzba, K.; Wilke, M.; Staudt, M.; Krageloh-Mann, I.; Grodd, W.

2008-01-01

Patients with congenital lesions of the left cerebral hemisphere may reorganize language functions into the right hemisphere. In these patients, language production is represented homotopically to the left-hemispheric language areas. We studied cerebellar activation in five patients with congenital lesions of the left cerebral hemisphere to assess…

Politics, Quality, and Passion: A Case Study of Reorganization in Higher Education. ASHE 1985 Annual Meeting Paper.

Science.gov (United States)

Reid, John Y.

The reorganization of the College of Education and Allied Professions at the University of Toledo is discussed. The analysis is based on Baldridge's political model, Bacharach and Lawler's views of politics and power, Pirsig's concept of quality, and the Oxford English Dictionary definitions of "passion." To investigate the…

Urgency of Community Supervision Organization by Government

Directory of Open Access Journals (Sweden)

Catur Wibowo Budi Santoso

2015-03-01

Full Text Available Urgency Surveillance Study of Social Organization aims to describe the reality of the problems in the a real of Social Organization; describe the implementation of the role of government (including local government in controlling the Social Organization; and provider recommendations on matters that need to be regulated in the draft regulations on the supervision of organizations. This study used a qualitative approach, with the aim that can be obtained in-depth and complete information about matters relating to the existence and dynamics in regional organizations. The study results presented can be: that on the one hand the existence of organizations that do not contribute little in development, but on the other hand there are many community organizations that act an archaic and disturbing in society; for the entire operational provisions for the implementation of Social Organization must be available; things that need to be arranged substantially in the surveillance by the government.

78 FR 43118 - Allegations of Anticompetitive Behavior in Satellite Industry

Science.gov (United States)

2013-07-19

... Competition Report. Pursuant to the Open-Market Reorganization for the Betterment of International...-Market Reorganization for the Betterment of International Telecommunications Act, 47 U.S.C. Sec. Sec. 701...

Prospects for Public School Revenues and Local School District Reorganization in Illinois in the 1980s.

Science.gov (United States)

Geske, Terry G.

Prospects for Illinois public school revenues and school district reorganization in the 1980's, considered in the context of prospects for the Great Lakes region as a whole, are affected by fundamental demographic and economic changes. The region has had a lower population growth rate since 1970 than the rest of the country, and a slower growth in…

Resilience and Water Governance: Adaptive Governance in the Columbia River Basin

Directory of Open Access Journals (Sweden)

Barbara A. Cosens

2012-12-01

Full Text Available The 1964 Columbia River Treaty between the United States and Canada is currently under review. Under the treaty, the river is jointly operated by the two countries for hydropower and is the largest producer of hydropower in the western hemisphere. In considering the next phase of international river governance, the degree of uncertainty surrounding the drivers of change complicates efforts to predict and manage under traditional approaches that rely on historical ecosystem responses. At the same time, changes in social values have focused attention on ecosystem health, the decline of which has led to the listing of seven salmon and four steelhead populations under the U.S. Endangered Species Act. Although adaptive management is considered one approach to resource management in the face of uncertainty, an early attempt at its implementation in the U.S. portion of the basin failed. We explore these issues in the context of resilience, taking the position that while adaptive management may foster ecological resilience, it is only one factor in the institutional changes needed to foster social-ecological resilience captured in the concept of adaptive governance.

Decomposing a Chunk into Its Elements and Reorganizing Them As a New Chunk: The Two Different Sub-processes Underlying Insightful Chunk Decomposition

Directory of Open Access Journals (Sweden)

Xiaofei Wu

2017-11-01

Full Text Available Familiar chunks can be processed highly efficiently, and this automatic process can prohibit the problem solver from developing novel and original ways to creatively solve difficult problems. For this reason, the role of the reverse process, chunk decomposition (CD, the process by which familiar patterns are broken down into their component elements in order to be regrouped in another meaningful manner, has been generally recognized as part of the creative process. However, previous studies on this issue have mainly focused on the decomposition process of CD (the D-process, while the reorganization process of CD has been greatly neglected or has not been distinctively identified in previous work. In this paper, we argue that the R-process could be equally as important as the D-process for CD. Even if a problem solver manages to decompose a familiar chunk into its elements, he or she still may not solve the problem if these elements are not successfully organized in a new and meaningful manner. To investigate whether the cognitive mechanism of the R-process is different from that of the D-process, we designed an experiment for detecting the effects of chunk tightness, which is regarded as the key factor in CD and which can be experimentally manipulated by the radical-level (loose and stroke-level (tight Chinese character CD tasks in the D-process, the R-process, and the more purified organization task (the O-process task that does not involve the decomposition process. Our results showed that the stroke-level (tight task was more difficult than the radical-level (loose task for the D-process. However, for the R-process, the stroke- and radical-level tasks showed no differences in performance. Moreover, for the more purified reorganization task, the O-process task, the radical-level organization and reorganization could be even more difficult than the stroke-level organization and reorganization. This result demonstrated that the cognitive

Actin re-organization induced by Chlamydia trachomatis serovar D--evidence for a critical role of the effector protein CT166 targeting Rac.

Directory of Open Access Journals (Sweden)

Jessica Thalmann

Full Text Available The intracellular bacterium Chlamydia trachomatis causes infections of urogenital tract, eyes or lungs. Alignment reveals homology of CT166, a putative effector protein of urogenital C. trachomatis serovars, with the N-terminal glucosyltransferase domain of clostridial glucosylating toxins (CGTs. CGTs contain an essential DXD-motif and mono-glucosylate GTP-binding proteins of the Rho/Ras families, the master regulators of the actin cytoskeleton. CT166 is preformed in elementary bodies of C. trachomatis D and is detected in the host-cell shortly after infection. Infection with high MOI of C. trachomatis serovar D containing the CT166 ORF induces actin re-organization resulting in cell rounding and a decreased cell diameter. A comparable phenotype was observed in HeLa cells treated with the Rho-GTPase-glucosylating Toxin B from Clostridium difficile (TcdB or HeLa cells ectopically expressing CT166. CT166 with a mutated DXD-motif (CT166-mut exhibited almost unchanged actin dynamics, suggesting that CT166-induced actin re-organization depends on the glucosyltransferase motif of CT166. The cytotoxic necrotizing factor 1 (CNF1 from E. coli deamidates and thereby activates Rho-GTPases and transiently protects them against TcdB-induced glucosylation. CNF1-treated cells were found to be protected from TcdB- and CT166-induced actin re-organization. CNF1 treatment as well as ectopic expression of non-glucosylable Rac1-G12V, but not RhoA-G14A, reverted CT166-induced actin re-organization, suggesting that CT166-induced actin re-organization depends on the glucosylation of Rac1. In accordance, over-expression of CT166-mut diminished TcdB induced cell rounding, suggesting shared substrates. Cell rounding induced by high MOI infection with C. trachomatis D was reduced in cells expressing CT166-mut or Rac1-G12V, and in CNF1 treated cells. These observations indicate that the cytopathic effect of C. trachomatis D is mediated by CT166 induced Rac1 glucosylation

Air traffic security act unconstitutional

International Nuclear Information System (INIS)

Heller, W.

2006-01-01

In the interest of more effective protective measures against terrorist attacks, the German federal parliament inter alia added a clause to the Air Traffic Security Act (Sec. 14, Para. 3, Air Traffic Security Act) empowering the armed forces to shoot down aircraft to be used as a weapon against human lives. In Germany, this defense possibility has been discussed also in connection with deliberate crashes of hijacked aircraft on nuclear power plants. The 1 st Division of the German Federal Constitutional Court, in its decision of February 15, 2006, ruled that Sec. 14, Para. 3, Air Traffic Security Act was incompatible with the Basic Law and thus was null and void (file No. 1 BvR 357/05) for two reasons: - There was no legislative authority on the part of the federal government. - The provision was incompatible with the basic right of life and the guarantee of human dignity as enshrined in the Basic Law. (orig.)

Drainage reorganization and divide migration induced by the excavation of the Ebro basin (NE Spain)

Science.gov (United States)

Vacherat, Arnaud; Bonnet, Stéphane; Mouthereau, Frédéric

2018-05-01

Intracontinental endorheic basins are key elements of source-to-sink systems as they preserve sediments eroded from the surrounding catchments. Drainage reorganization in such a basin in response to changing boundary conditions has strong implications on the sediment routing system and on landscape evolution. The Ebro and Duero basins represent two foreland basins, which developed in response to the growth of surrounding compressional orogens, the Pyrenees and the Cantabrian mountains to the north, the Iberian Ranges to the south, and the Catalan Coastal Range to the east. They were once connected as endorheic basins in the early Oligocene. By the end of the Miocene, new post-orogenic conditions led to the current setting in which the Ebro and Duero basins are flowing in opposite directions, towards the Mediterranean Sea and the Atlantic Ocean. Although these two hydrographic basins recorded a similar history, they are characterized by very different morphologic features. The Ebro basin is highly excavated, whereas relicts of the endorheic stage are very well preserved in the Duero basin. The contrasting morphological preservation of the endorheic stage represents an ideal natural laboratory to study the drivers (internal and/or external) of post-orogenic drainage divide mobility, drainage network, and landscape evolution. To that aim, we use field and map observations and we apply the χ analysis of river profiles along the divide between the Ebro and Duero drainage basins. We show here that the contrasting excavation of the Ebro and Duero basins drives a reorganization of their drainage network through a series of captures, which resulted in the southwestward migration of their main drainage divide. Fluvial captures have a strong impact on drainage areas, fluxes, and their respective incision capacity. We conclude that drainage reorganization driven by the capture of the Duero basin rivers by the Ebro drainage system explains the first-order preservation of

Good Governance According to Islamic Perspective

Directory of Open Access Journals (Sweden)

Mohamad Ismail Bin Mohamad Yunus

2018-02-01

Full Text Available Abstract The objectives of the professional agencies must embody provisions that promote good governance and embrace values of integrity and accountability and seek support from the public and the government of the day to provide an independent view on all matters. The universal truth is that everything should be done in the public good. Professionals form the backbone of human infrastructure in any economy, politics, social and legal growth. Their contributions through professional performance enhance the good delivery system that facilitates policies making and management for public sector. They provide the skills and talent in balancing the pursuits of maximization of services. The expression “good governance” has been constantly used lately in both public sector as well as private sector in Malaysia. In the context of a private body, it should be within the framework of the statute, which governs the body and also its constitution. In the public sector, it means that the administrators should act professionally and not to abuse or misuse the power or authority given to them. They are regarded as the trustees of the public at large. The scope of this article is on good public governance in the public sector or to be exact, good governmental administration as interpreted by the judiciary especially through its judicial review power and Islamic Perspective based on the principles of Maqasid As Shariah (Objectives of Islamic Law.   Keywords: Good Governance, Public Sector, Malaysian Law, Islamic Perspective, Maqasid As-Shariah.

Reorganization of Language Areas in Patient with a Frontal Lobe Low Grade Glioma – fMRI Case Study

International Nuclear Information System (INIS)

Kośla, Katarzyna; Bryszewski, Bartosz; Jaskólski, Dariusz; Błasiak-Kołacińska, Nina; Stefańczyk, Ludomir; Majos, Agata

2015-01-01

Functional magnetic resonance (fMRI) studies results in case of an adult patient with low grade glioma (LGG) in dominant hemisphere suggest brain plasticity process with acquisition of language functions by the non-dominant hemisphere speech regions. A 36-years old right-handed woman was admitted to the Department of Neurosurgery for surgical treatment of brain tumor. An MRI examination revealed a pathological mass in the left frontal lobe, in close topographical relationship to the Broca’s area. A left fronto-parietal craniotomy was performed, with an intraoperative awake language mapping procedure. A total resection of the pathological mass was achieved. The tumor was examined histologically as LGG. In the follow-up MRI exam 32 months after the operation a tumor recurrence was suggested. The fMRI exams performed preoperative and 3, 32 and 41 months after the operation showed changes in language regions activation patterns, with a progressive right-sided activation of Broca’s and Wernicke’s areas. Pre- and postoperative cognitive evaluation by a neuropsychologist did not detect any language impairment. We present a running process of reorganization of language areas in a patient after brain tumor resection, from strong left-sided to symmetrical lateralization. 1. FMRI results in comparison with the psychological status of the patient proved contribution of functional reorganization to the preservation of language performance. 2. A slow growing LGG as well as the recurrence of the tumor near the left Broca’s area might be the factors leading to reorganization of language-related areas by recruiting the right hemisphe

Beyond formal groups: neighboring acts and watershed protection in Appalachia

Directory of Open Access Journals (Sweden)

Heather Lukacs

2016-09-01

Full Text Available This paper explores how watershed organizations in Appalachia have persisted in addressing water quality issues in areas with a history of coal mining. We identified two watershed groups that have taken responsibility for restoring local creeks that were previously highly degraded and sporadically managed. These watershed groups represent cases of self-organized commons governance in resource-rich, economically poor Appalachian communities. We describe the extent and characteristics of links between watershed group volunteers and watershed residents who are not group members. Through surveys, participant observation, and key-informant consultation, we found that neighbors – group members as well as non-group-members – supported the group's function through informal neighboring acts. Past research has shown that local commons governance institutions benefit from being nested in supportive external structures. We found that the persistence and success of community watershed organizations depends on the informal participation of local residents, affirming the necessity of looking beyond formal, organized groups to understand the resources, expertise, and information needed to address complex water pollution at the watershed level. Our findings augment the concept of nestedness in commons governance to include that of a formal organization acting as a neighbor that exchanges informal neighboring acts with local residents. In this way, we extend the concept of neighboring to include interactions between individuals and a group operating in the same geographic area.

Act No. 80-572 on protection and control of nuclear materials

International Nuclear Information System (INIS)

1980-01-01

This Act lays down that the import, export, possession, transfer, use and transport of nuclear materials defined by the Act are subject to licensing and control under conditions to be determined by Decree. The purpose of this control is to avoid loss, theft or diversion of such materials. Any person who obtains fraudulently nuclear material referred to in the Act or who carries out activities involving such material without the required licence shall be subject to severe penalties. Finally, it is provided that the Government shall report to Parliament each year on operation of the provisions of this Act. (NEA) [fr

Effect of a reorganized after-hours family practice service on frequent attenders

DEFF Research Database (Denmark)

Vedsted, Peter; Olesen, Frede

1999-01-01

of this reorganization on the use of services by frequent attenders (FAs). METHODS: From 1990 to 1994, methods of contact and annual costs per attender were analyzed in an ecological time-trend study based on aggregated administrative data collected from the database of the Public Health Insurance, Aarhus County......, Denmark (600,000 inhabitants). The study only included attenders ages 18 and over. FAs were defined as the group that, within each calendar year (12 months), had 4 or more contacts with the after-hours family practice service. RESULTS: FAs made up 9.5% of the attenders and accounted for more than 40...

The evolution of corporate governance in the global financial crisis: the case of Russian industrial firms

Directory of Open Access Journals (Sweden)

Ichiro Iwasaki

2016-12-01

Full Text Available In this paper, using a unique dataset of industrial firms obtained from enterprise surveys conducted across the Russian Federation in 2005 and 2009, we trace back structural changes in the corporate governance system before and after the global financial crisis. We also empirically examine the impacts of the crisis on the organization of boards of directors and audit systems. Our survey results reveal that, in the Russian industrial sector, the quality of corporate governance has been improved through the crisis. Furthermore, we found that, corresponding to the alignment hypothesis, in firms that decisively reformed their management and supervisory bodies in response to the 2008 financial shock, the total number of worker representative directors significantly declined, as did their proportion to all board members. On the other hand, we also found that, in firms that substantially reorganized their audit system to cope with the crisis, the independence of the audit system was undermined remarkably, corresponding to the expropriation hypothesis. Findings that management behaviors predicted by the two conflicting hypotheses are simultaneously detected—and that their targets are significantly different—deserve special mention.

77 FR 69491 - Privacy Act of 1974: System of Records; Secure Flight Records

Science.gov (United States)

2012-11-19

... page at http://www.regulations.gov ; (2) Accessing the Government Printing Office's Web page at http...) of the Intelligence Reform and Terrorism Prevention Act of 2004 (IRTPA),\\4\\ Congress directed TSA and... Intelligence Agency, the Secretary of the Treasury, and the Secretary of Defense. The Attorney General, acting...

Climate governance entrepreneurship: Emerging findings and a new research agenda

NARCIS (Netherlands)

Lerum Boasson, E.; Huitema, D.

2017-01-01

This is an introductory paper to a special issue on climate governance entrepreneurship, where entrepreneurship is understood as acts performed by actors seeking to ‘punch above their weight’. By contrast, actors who are merely doing their job are not ‘entrepreneurs’. In order to understand climate

Adherence to the spirit of corporate governance : the ethics of executive remuneration

OpenAIRE

2013-01-01

M.Comm. (Industrial Psychology) With the implementation of King III in 2010 and the promulgation of the new Companies Act in 2011, the corporate governance landscape in South Africa was irrevocably changed. Simultaneously, there was an increase in the protestations against the perceived excesses of executive1 remuneration packages. The question posed in this research study was what does adherence to the spirit of corporate governance with regard to executive remuneration entail? The litera...

Government Policy and the Banking Crisis: Vindicated, Misled or Flying Blind?

OpenAIRE

Tobin, Damian; TASC

2010-01-01

Almost three years after the onset of Ireland's banking criris public disenchantment continues to increase, aggravated in part by the government's failure to provide a transparent examination for the crisis and an endless stream of revelations on the increasing cost of stabilising the banking system. The government claimed that it acted on the "best available advice" and as a consequence has been able to pin the blame for the crisis on events beyond its control. This think piece argues that t...

76 FR 31017 - Advisory Group to the Internal Revenue Service Tax Exempt and Government Entities Division (TE/GE...

Science.gov (United States)

2011-05-27

... Government Accountability Office (GAO) Report to Congressional Requesters Entitled ``Social Security... site. Indian Tribal Governments: --Supplemental Report on the Implementation of Tribal Economic Development Bonds Under the American Recovery and Reinvestment Act of 2009. --Survey of Issues Requiring...

Cultural differences in perceptual reorganization in US and Pirahã adults.

Directory of Open Access Journals (Sweden)

Jennifer M D Yoon

Full Text Available Visual illusions and other perceptual phenomena can be used as tools to uncover the otherwise hidden constructive processes that give rise to perception. Although many perceptual processes are assumed to be universal, variable susceptibility to certain illusions and perceptual effects across populations suggests a role for factors that vary culturally. One striking phenomenon is seen with two-tone images-photos reduced to two tones: black and white. Deficient recognition is observed in young children under conditions that trigger automatic recognition in adults. Here we show a similar lack of cue-triggered perceptual reorganization in the Pirahã, a hunter-gatherer tribe with limited exposure to modern visual media, suggesting such recognition is experience- and culture-specific.

75 FR 31699 - Indian Self-Determination Act Contracts and Annual Funding Agreements-Appeal Procedures

Science.gov (United States)

2010-06-04

... Indian Self-Determination Act Contracts and Annual Funding Agreements--Appeal Procedures AGENCIES: Bureau... Contract Disputes Act, 41 U.S.C. 601-613. Effective January 6, 2007, Congress abolished the Interior Board... technical amendments to their joint regulations governing contracts and annual funding agreements under the...

Governance Challenges in Telecoupled Food Systems

Science.gov (United States)

Eakin, H.; Mahanti, A.; Rueda, X.

2015-12-01

Distal connections increasingly influence food systems' governance: social actors in one geographic context produce intended and unintended consequences in distant locations, coupling the dynamics of socio-ecological systems. While these linkages are not new, economic globalization, urbanization and the dynamics of consumer preferences have accentuated these 'telecoupled' relationships in food systems. Telecoupling refers to the unexpected causal interactions among human-environment systems that were otherwise not linked. This paper presents a framework for evaluating telecoupling processes and outcomes in food systems, focusing on how the disparate scales of drivers and outcomes, diverse values of actors involved, and spatial and social distance combine to challenge socio-ecological system governance. We draw from two examples of food systems (coffee and maize) to argue that telecoupling, as a challenge for food systems, emerges when the institutions and mechanisms of governance acting over one system do not account for the consequences and interactions involving a different system. Telecoupling can stimulate new forms of governance, such as the development of codes of conduct and certification schemes, with positive impacts on food and livelihood security. Our cases suggest that the emergence of new governance arrangements is at least partially contingent on the prior existence of alternative social networks, which cultivate shared values, meanings and goals in food systems, as well as the capacity of affected actors to mobilize political influence and demonstrate plausible causal links. In the absence of such networks and associated capacities, the prior governance arrangements, although poorly adjusted to the new circumstances, are likely to persist, reinforcing existing power relations and the probability of undesirable social and ecological outcomes.

Government Performance and Results Act: Performance plan FY 1999, U.S. Nuclear Regulatory Commission. Volume 1

International Nuclear Information System (INIS)

Fuches, J.L.

1998-02-01

The Nuclear Regulatory Commission's (NRC) strategic plan [NUREG-1614, Vol. 1, September 1997] establishes a strategic framework that will guide future decision-making and will help the NRC continue to meet its responsibility for protecting public health and safety, promoting the common defense and security, and protecting the environment. This performance plan complements the agency's strategic plan by setting annual goals with measurable target levels of performance for FY 1999, as required by the Government Performance and Results Act. No significant contribution was made to the preparation of the performance plan by any non-Federal entity. However, a contractor was used to help facilitate discussions and resolution of issues. Within six months after the close of FY 1999, the NRC will submit to the President and the Congress a report on program performance for FY 1999. This performance report will review the success of the agency in achieving the performance goals established for FY 1999. Where those goals have been achieved, the underlying assumptions and strategies will be examined to ensure that continued applicability is warranted in the future. If any of the FY 1999 performance goals are not met, the agency will conduct a thorough analysis of why it did not meet the goal and the actions necessary to meet-the goal in the future. One result of this analysis will be the documentation of plans and schedules for achieving the established performance goal. If the analysis should indicate that the performance goal is impractical or infeasible, the performance report will document why that is the case and what action is recommended

The Specifics of Tax Arbitrage in The Reorganization of The European Companies Through Acquisitions, Mergers, Spin-Offs and Disinvestments

Directory of Open Access Journals (Sweden)

Anda Simona Rădulescu (Dîrvă

2016-03-01

Full Text Available Focusing on fiscal issues, in this paper we analyzed the trend of European companies to streamline their activity through legal reorganization (i.e. takeovers, mergers, spin-offs, divestments starting from tax benefits which may result from such operations.

Protein degradation during reconsolidation as a mechanism for memory reorganization

Directory of Open Access Journals (Sweden)

Bong-Kiun Kaang

2011-02-01

Full Text Available Memory is a reference formed from a past experience that is used to respond to present situations. However, the world is dynamic and situations change, so it is important to update the memory with new information each time it is reactivated in order to adjust the response in the future. Recent researches indicate that memory may undergo a dynamic process that could work as an updating mechanism. This process which is called reconsolidation involves destabilization of the memory after it is reactivated, followed by restabilization. Recently, it has been demonstrated that the initial destabilization process of reconsolidation requires protein degradation. Using protein degradation inhibition as a method to block reconsolidation, recent researches suggest that reconsolidation, especially the protein degradation-dependent destabilization process is necessary for memory reorganization.

Quick profile-reorganization driven by helical field perturbation for suppressing tokamak major disruptions

International Nuclear Information System (INIS)

Yamazaki, K.; Kawahata, K.; Ando, R.

1986-09-01

Disruptive behavior of magnetic field configuration leading to tokamak major disruption is found to be controlled by a mild ''mini-disruption'' which is induced by the compact external modular multipole-field coils with m = 3/n = 2 dominant helical field component in the JIPP T-IIU tokamak. This mini-disruption ergodizes the m = 2/n = 1 magnetic island quickly but mildly and then prevents the profile of electron temperature from flattening. This quick profile-reorganization is effective to avoid the two-step disruption (pre- and major disuptions) responsible for the chatastrophic current termination. (author)

P.L. 96-294, "Energy Security Act" (1980)

Energy Technology Data Exchange (ETDEWEB)

None

2011-12-13

Declares it to be the purpose of this title to reduce dependence on foreign energy resources by producing synthetic fuel. Part A: Development of Synthetic Fuel Under the Defense Production Act of 1950 - Defense Production Act Amendments of 1980 - Amends the Defense Production Act of 1950 to include within the policy objectives of such Act Government preparedness to contend with foreign actions which could reduce or terminate the availability of material, including energy, which is crucial to national defense. States that greater independence in domestic energy supplies is necessary to national defense preparedness. Designates "energy" as a "strategic and critical material." States that such designation shall not give the President any authority: (1) for the mandatory allocation or pricing of any fuel or feedstock; or (2) to engage in the production of energy in any manner whatsoever, except for synthetic fuel production.

Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry

Directory of Open Access Journals (Sweden)

Irina V. Gorudko

2013-07-01

Myeloperoxidase (MPO is a heme-containing enzyme released from activated leukocytes into the extracellular space during inflammation. Its main function is the production of hypohalous acids that are potent oxidants. MPO can also modulate cell signaling and inflammatory responses independently of its enzymatic activity. Because MPO is regarded as an important risk factor for cardiovascular diseases associated with increased platelet activity, we studied the effects of MPO on human platelet functional properties. Laser scanning confocal microscopy was used to reveal carbohydrate-independent MPO binding to human platelet membrane. Adding MPO to platelets did not activate their aggregation under basal conditions (without agonist. In contrast, MPO augmented agonist-induced platelet aggregation, which was not prevented by MPO enzymatic activity inhibitors. It was found that exposure of platelets to MPO leads to actin cytoskeleton reorganization and an increase in their elasticity. Furthermore, MPO evoked a rise in cytosolic Ca2+ through enhancement of store-operated Ca2+ entry (SOCE. Together, these findings indicate that MPO is not a direct agonist but rather a mediator that binds to human platelets, induces actin cytoskeleton reorganization and affects the mechanical stiffness of human platelets, resulting in potentiating SOCE and agonist-induced human platelet aggregation. Therefore, an increased activity of platelets in vascular disease can, at least partly, be provided by MPO elevated concentrations.

Feeding cells induced by phytoparasitic nematodes require γ-tubulin ring complex for microtubule reorganization.

Directory of Open Access Journals (Sweden)

Mohamed Youssef Banora

2011-12-01

Full Text Available Reorganization of the microtubule network is important for the fast isodiametric expansion of giant-feeding cells induced by root-knot nematodes. The efficiency of microtubule reorganization depends on the nucleation of new microtubules, their elongation rate and activity of microtubule severing factors. New microtubules in plants are nucleated by cytoplasmic or microtubule-bound γ-tubulin ring complexes. Here we investigate the requirement of γ-tubulin complexes for giant feeding cells development using the interaction between Arabidopsis and Meloidogyne spp. as a model system. Immunocytochemical analyses demonstrate that γ-tubulin localizes to both cortical cytoplasm and mitotic microtubule arrays of the giant cells where it can associate with microtubules. The transcripts of two Arabidopsis γ-tubulin (TUBG1 and TUBG2 and two γ-tubulin complex proteins genes (GCP3 and GCP4 are upregulated in galls. Electron microscopy demonstrates association of GCP3 and γ-tubulin as part of a complex in the cytoplasm of giant cells. Knockout of either or both γ-tubulin genes results in the gene dose-dependent alteration of the morphology of feeding site and failure of nematode life cycle completion. We conclude that the γ-tubulin complex is essential for the control of microtubular network remodelling in the course of initiation and development of giant-feeding cells, and for the successful reproduction of nematodes in their plant hosts.

Factors Influencing Water Resource Governance among Pastoral Community at Mkondoa Sub-Catchment Morogoro Region Tanzania

OpenAIRE

Yeremia Yohana Masifia; Sarone Ole Sena

2017-01-01

The importance of proper Water Resource Management with greater emphasis on ensuring sustainability quality accountability and community participation has become imminent as water resources increasingly become scarce Harvey et al 2007. Water resources management in Tanzania is governed under the National Water Policy of 2002 and Water Resources Management Act No.11 of year 2009. Other related legislations include Environmental Management Act No. 20 of year 2004 Forest Policy and Forest Act No...

Corporate governance and executive pay: evidence from a recent reform

Czech Academy of Sciences Publication Activity Database

Paligorova, Teodora

-, č. 331 (2007), s. 1-49 ISSN 1211-3298 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:AV0Z70850503 Keywords : corporate governance * the Sarbanes-Oxley Act * incentive pay Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp331.pdf

Plans of reorganization of USA nuclear military complex and provision of military program by special nuclear materials

International Nuclear Information System (INIS)

Semenovskaya, I.V.

1996-01-01

Consideration is given to plans and implementation of the program of reorganization of USA nuclear military complex, related with conducted reduction of nuclear arsenal after concluding the Strategic Nuclear Armament Reduction Treaty. Particular attention is paid to problems of satisfying short-term and long-term requirements in special nuclear materials and in tritium in particular

1992 Nuclear Regulatory Commission Annual Report

International Nuclear Information System (INIS)

1993-01-01

This is the 18th annual report of the US Nuclear Regulatory Commission (NRC), covering events and activities occurring in fiscal year 1992 (the year ending September 30, 1992), with some treatment of events from the last quarter of calendar year 1992. The NRC was created by enactment in the Congress of the Energy Reorganization Act of 1974. It is an independent agency of the Federal Government. The five NRC Commissioners are nominated by the President and confirmed by the United States Senate. The Chairman of the Commission is appointed by the President from among the Commissioners confirmed

77 FR 48199 - Privacy Act; System of Records: State-35, Information Access Programs Records

Science.gov (United States)

2012-08-13

..., the Privacy Act, the Ethics in Government Act, the access provisions of Executive Order 13526 or a...; requester's name and requester's mailing and email address; Social Security number (if provided by the...: Hard copy and electronic media. RETRIEVABILITY: Individual name, case number. SAFEGUARDS: All users are...

Transnational Climate Change Governance and the Global South

OpenAIRE

Chan, Sander; van Asselt, Harro; Forschungszentrum für Umweltpolitik

2018-01-01

Alongside intergovernmental climate change negotiations, a groundswell of climate actions by cities, regions, businesses, investors, and civil society groups has emerged. These transnational actors seek to address mitigation and adaptation to climate change; independently, with each other and with governments and international organizations. Many have welcomed transnational climate initiatives as a crucial addition to the formal climate regime, contributing to a growing momentum to act on cli...

Evaluating e-Government and Good Governance Correlation

Directory of Open Access Journals (Sweden)

Suhardi Suhardi

2016-03-01

Full Text Available Assessing the achievement of Indonesian government institutions in implementing e-government has been conducted since around a decade ago. Several national assessments are available with almost the same ranking results. There is an agreement that the ultimate goal of e-government implementation is to achieve good government governance (GGG, while success stories of e-government require good governance practices. This study explored the correlation between e-government achievement and GGG achievement in Indonesia. Spearman’s rank correlation was used to characterize the relationship strength between e-government assessment results and good governance assessment results. The data were collected from institutions that participated in e-government and good governance assessments. The results showed that the correlation between these two entities is not very strong. Most cases showed that e-government implementation and the achievement of good governance have only a moderate positive correlation and none of the studied cases indicated a significant connection. This result can be attributed to the lack of emphasis on goals achievement in the assessments. Thus, it is recommended that future Indonesian e-government assessments should involve impact indicators.

75 FR 80762 - Medicare Program; Emergency Medical Treatment and Labor Act: Applicability to Hospital and...

Science.gov (United States)

2010-12-23

... [CMS-1350-ANPRM] RIN 0938-AQ51 Medicare Program; Emergency Medical Treatment and Labor Act... Emergency Medical Treatment and Labor Act (EMTALA). Specifically, this document serves as a request for... available to persons without Federal government identification, commenters are encouraged to leave their...

77 FR 5213 - Medicare Program; Emergency Medical Treatment and Labor Act (EMTALA): Applicability to Hospital...

Science.gov (United States)

2012-02-02

... [CMS-1350-NC] RIN 0938-AQ51 Medicare Program; Emergency Medical Treatment and Labor Act (EMTALA... the applicability of the Emergency Medical Treatment and Labor Act (EMTALA) to hospital inpatients... available to persons without Federal government identification, commenters are encouraged to leave their...

77 FR 23173 - Privacy Act of 1974: Implementation

Science.gov (United States)

2012-04-18

... a significant economic impact on a substantial number of small entities. Paperwork Reduction Act The... governments, and the private sector. UMRA requires a written statement of economic and regulatory alternatives... subsections (c)(3); (d)(1), (2), (3) and (4); and (e)(1): (1) Air Intelligence Program (Justice/DEA-001) (2...

Improvement of clinical quality indicators through reorganization of the acute care by establishing an emergency department-a register study based on data from national indicators.

Science.gov (United States)

Mattsson, Maria Søe; Mattsson, Nick; Jørsboe, Hanne B

2014-11-05

The Emergency Departments (EDs) reorganization process in Denmark began in 2007 and includes creating a single entrance for all emergency patients, establishing triage, having a specialist in the front and introducing the use of electronic overview boards and electronic patient files. The aim of this study was to investigate the quality of acute care in a re-organized ED based on national indicator project data in a pre and post reorganizational setting. Quasi experimental design was used to examine the effect of the health care quality in relation to the reorganization of an ED. Patients admitted at Nykøbing Falster Hospital in 2008 or 2012 were included in the study and data reports from the national databases (RKKP) regarding stroke, COPD, heart failure, bleeding and perforated ulcer or hip fracture were analysed. Holbæk Hospital works as a control hospital. Chi-square test was used for analysing significant differences from pre-and post intervention and Z-test to compare the experimental groups to the control group (HOL). P cases from RKKP. A significant positive change was seen in all of the additional eight indicators related to stroke at NFS (P < 0.001); however, COPD indicators were unchanged in both hospitals. In NFS two of eight heart failure indicators were significantly improved after the reorganization (p < 0.01). In patients admitted with a bleeding ulcer 2 of 5 indicators were significantly improved after the reorganization in NFS and HOL (p < 0.01). Both compared hospitals showed significant improvements in the two indicators concerning hip fracture (p < 0.001). Significant reductions in the 30 day-mortality in patients admitted with stroke were seen when the pre- and the post-intervention data were compared for both NFS and HOL (p = 0.024). During the organisation of the new EDs, several of the indicators improved and the overall 30 days mortality decreased in the five diseases. The development of a common set of

Adapting adaptation: the English eco-town initiative as governance process

Directory of Open Access Journals (Sweden)

Daniel Tomozeiu

2014-06-01

Full Text Available Climate change adaptation and mitigation have become key policy drivers in the UK under its Climate Change Act of 2008. At the same time, urbanization has been high on the agenda, given the pressing need for substantial additional housing, particularly in southeast England. These twin policy objectives were brought together in the UK government's 'eco-town' initiative for England launched in 2007, which has since resulted in four eco-town projects currently under development. We critically analyze the eco-town initiative's policy evolution and early planning phase from a multilevel governance perspective by focusing on the following two interrelated aspects: (1 the evolving governance structures and resulting dynamics arising from the development of the eco-town initiative at UK governmental level, and the subsequent partial devolution to local stakeholders, including local authorities and nongovernmental actors, under the new 'localism' agenda; and (2 the effect of these governance dynamics on the conceptual and practical approach to adaptation through the emerging eco-town projects. As such, we problematize the impact of multilevel governance relations, and competing governance strategies and leadership, on shaping eco-town and related adaptation strategies and practice.

78 FR 53194 - Advisory Group to the Internal Revenue Service Tax Exempt and Government Entities Division (TE/GE...

Science.gov (United States)

2013-08-28

... DEPARTMENT OF THE TREASURY Internal Revenue Service Advisory Group to the Internal Revenue Service Tax Exempt and Government Entities Division (TE/GE); Meeting AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice. SUMMARY: The Advisory Committee on Tax Exempt and Government Entities (ACT) will...

Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4

Directory of Open Access Journals (Sweden)

Sachiko Homma

2016-12-01

Full Text Available Abstract Background Nuclear bodies, such as nucleoli, PML bodies, and SC35 speckles, are dynamic sub-nuclear structures that regulate multiple genetic and epigenetic processes. Additional regulation is provided by RNA/DNA handling proteins, notably TDP-43 and FUS, which have been linked to ALS pathology. Previous work showed that mouse cell line myotubes have fewer but larger nucleoli than myoblasts, and we had found that nuclear aggregation of TDP-43 in human myotubes was induced by expression of DUX4-FL, a transcription factor that is aberrantly expressed and causes pathology in facioscapulohumeral dystrophy (FSHD. However, questions remained about nuclear bodies in human myogenesis and in muscle disease. Methods We examined nucleoli, PML bodies, SC35 speckles, TDP-43, and FUS in myoblasts and myotubes derived from healthy donors and from patients with FSHD, laminin-alpha-2-deficiency (MDC1A, and alpha-sarcoglycan-deficiency (LGMD2D. We further examined how these nuclear bodies and proteins were affected by DUX4-FL expression. Results We found that nucleoli, PML bodies, and SC35 speckles reorganized during differentiation in vitro, with all three becoming less abundant in myotube vs. myoblast nuclei. In addition, though PML bodies did not change in size, both nucleoli and SC35 speckles were larger in myotube than myoblast nuclei. Similar patterns of nuclear body reorganization occurred in healthy control, MDC1A, and LGMD2D cultures, as well as in the large fraction of nuclei that did not show DUX4-FL expression in FSHD cultures. In contrast, nuclei that expressed endogenous or exogenous DUX4-FL, though retaining normal nucleoli, showed disrupted morphology of some PML bodies and most SC35 speckles and also co-aggregation of FUS with TDP-43. Conclusions Nucleoli, PML bodies, and SC35 speckles reorganize during human myotube formation in vitro. These nuclear body reorganizations are likely needed to carry out the distinct gene transcription and

The Association Between Workers' Employability and Burnout in a Reorganization Context: Longitudinal Evidence Building Upon the Conservation of Resources Theory

NARCIS (Netherlands)

de Cuyper, Nele; Raeder, Sabine; van der Heijden, Beatrice; Wittekind, Anette

2012-01-01

This longitudinal study probes the relationship between employability and burnout among employees from a company undergoing reorganization. We advanced employability as a personal resource that relates negatively to burnout. We expected that this hypothesis would hold for different

An Analysis of 19 International Case Studies of Stress Prevention Through Work Reorganization Using the Demand/Control Model

Science.gov (United States)

Karasek, Robert A.

2004-01-01

Nineteen international case studies of workplace stress prevention initiatives are analyzed. The focus of these cases, which span a variety of workplaces and locations, is on preventing stress through work reorganization rather than remedial approaches for stress relief. It is found that the majority of the occupations represented in the case…

17 CFR 201.520 - Suspension of registration of brokers, dealers, or other Exchange Act-registered entities...

Science.gov (United States)

2010-04-01

... brokers, dealers, or other Exchange Act-registered entities: Application. 201.520 Section 201.520... Rules Relating to Temporary Orders and Suspensions § 201.520 Suspension of registration of brokers... of a registered broker, dealer, municipal securities dealer, government securities broker, government...

3 CFR - Continuation of the National Emergency With Respect to the Actions of the Government of Syria

Science.gov (United States)

2010-01-01

... to the Actions of the Government of Syria Presidential Documents Other Presidential Documents Notice... of Syria On May 11, 2004, pursuant to his authority under the International Emergency Economic Powers Act, 50 U.S.C. 1701-1706, and the Syria Accountability and Lebanese Sovereignty Restoration Act of...

75 FR 80313 - Privacy Act of 1974; Implementation

Science.gov (United States)

2010-12-22

... Act, 5 U.S.C. 601-612, therefore, the proposed rule will not have a significant economic impact on a... that are contributed to DIVS are created by the FBI or other law enforcement and intelligence entities..., and tribal governments, and the private sector. UMRA requires a written statement of economic and...

34 CFR 400.8 - What are the provisions governing student assistance?

Science.gov (United States)

2010-07-01

... portion of any student financial assistance received under the Act that is made available for attendance... 34 Education 3 2010-07-01 2010-07-01 false What are the provisions governing student assistance...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION VOCATIONAL AND APPLIED TECHNOLOGY...

Revision of the law governing the energy industry; Neuregelung des Energierechts

Energy Technology Data Exchange (ETDEWEB)

Anon,

1993-11-03

In its report on measures for safeguarding the competitiveness of the German industry, the Federal Government announced a number of reforms covering among others a revision of the regulatory framework governing the electricity and gas industry. Major goals in this context are deregulation and an enhancement of competition. The Federal Ministry of Economics prepared a draft plan for action addressing the need for an amendment of the Energy Management Act and the Act Against Restraints on Competition. Implementation of the measures given in the draft plan would create completely new conditions for the pipeline energy supply industry. (orig./HSCH) [Deutsch] Die Bundesregierung hat in ihrem Bericht zur Zukunftssicherung des Wirtschaftsstandorts Deutschland auch die Reform des Ordnungsrahmens fuer Strom und Gas angekuendigt. Ziel dieser Reform sollen Wettbewerb und Deregulierung sein. Das Bundeswirtschaftsministerium hat dazu auf Fachebene ein Konzept erarbeitet, das ein neues Energiewirtschaftsgesetz sowie eine Aenderung des Gesetzes gegen Wettbewerbsbeschraenkungen umfasst. Das Konzept wuerde die leitungsgebundene Versorgungswirtschaft auf eine voellig neue Grundlage stellen. (orig./HSCH)

Government Performance and Results Act: Performance plan FY 1999, U.S. Nuclear Regulatory Commission. Volume 1

Energy Technology Data Exchange (ETDEWEB)

Fuches, J.L.

1998-02-01

The Nuclear Regulatory Commission`s (NRC) strategic plan [NUREG-1614, Vol. 1, September 1997] establishes a strategic framework that will guide future decision-making and will help the NRC continue to meet its responsibility for protecting public health and safety, promoting the common defense and security, and protecting the environment. This performance plan complements the agency`s strategic plan by setting annual goals with measurable target levels of performance for FY 1999, as required by the Government Performance and Results Act. No significant contribution was made to the preparation of the performance plan by any non-Federal entity. However, a contractor was used to help facilitate discussions and resolution of issues. Within six months after the close of FY 1999, the NRC will submit to the President and the Congress a report on program performance for FY 1999. This performance report will review the success of the agency in achieving the performance goals established for FY 1999. Where those goals have been achieved, the underlying assumptions and strategies will be examined to ensure that continued applicability is warranted in the future. If any of the FY 1999 performance goals are not met, the agency will conduct a thorough analysis of why it did not meet the goal and the actions necessary to meet-the goal in the future. One result of this analysis will be the documentation of plans and schedules for achieving the established performance goal. If the analysis should indicate that the performance goal is impractical or infeasible, the performance report will document why that is the case and what action is recommended.

Reorganization of syntactic processing following left-hemisphere brain damage: does right-hemisphere activity preserve function?

OpenAIRE

Tyler, Lorraine K.; Wright, Paul; Randall, Billi; Marslen-Wilson, William D.; Stamatakis, Emmanuel A.

2010-01-01

The extent to which the human brain shows evidence of functional plasticity across the lifespan has been addressed in the context of pathological brain changes and, more recently, of the changes that take place during healthy ageing. Here we examine the potential for plasticity by asking whether a strongly left-lateralized system can successfully reorganize to the right-hemisphere following left-hemisphere brain damage. To do this, we focus on syntax, a key linguistic function considered to b...

24 CFR 180.415 - Notice of proposed adverse action regarding Federal financial assistance in non-Fair Housing Act...

Science.gov (United States)

2010-04-01

... regarding Federal financial assistance in non-Fair Housing Act matters. 180.415 Section 180.415 Housing and... proposed adverse action regarding Federal financial assistance in non-Fair Housing Act matters. (a) Filing... govern the proceeding. (c) Consolidation. The ALJ may provide for non-Fair Housing Act proceedings at HUD...

SPEECH ACT ANALYSIS: HOSNI MUBARAK'S SPEECHES IN PRE ...

African Journals Online (AJOL)

enerco

from movements of certain organs with his (man‟s) throat and mouth…. By means ... In other words, government engages language; and how this affects the ... address the audience in a social gathering in order to have a new dawn. ..... Agbedo, C. U. Speech Act Analysis of Political discourse in the Nigerian Print Media in.

Act of 19 June 1974 on Compensation for Nuclear Damage

International Nuclear Information System (INIS)

1974-01-01

This Act which came into force on 18 September 1974 replaces the nuclear third party liability provisions of the 1962 Act on nuclear installations. Its adoption enabled the Danish Government to ratify the 1960 Paris Convention and the 1963 Brussels Supplementary Convention. In accordance with the principles prescribed by these Conventions, the Act establishes an absolute and limited third party liability system (75 million Danish Krone) and compulsory insurance for the operator of a nuclear installation situated in Denmark. In certain conditions, the State may have to intervene to ensure compensation of nuclear damage exceeding the financial security provided by the operator liable. (NEA) [fr

Neural Patterns of Reorganization after Intensive Robot-Assisted Virtual Reality Therapy and Repetitive Task Practice in Patients with Chronic Stroke

Directory of Open Access Journals (Sweden)

Soha Saleh

2017-09-01

Full Text Available Several approaches to rehabilitation of the hand following a stroke have emerged over the last two decades. These treatments, including repetitive task practice (RTP, robotically assisted rehabilitation and virtual rehabilitation activities, produce improvements in hand function but have yet to reinstate function to pre-stroke levels—which likely depends on developing the therapies to impact cortical reorganization in a manner that favors or supports recovery. Understanding cortical reorganization that underlies the above interventions is therefore critical to inform how such therapies can be utilized and improved and is the focus of the current investigation. Specifically, we compare neural reorganization elicited in stroke patients participating in two interventions: a hybrid of robot-assisted virtual reality (RAVR rehabilitation training and a program of RTP training. Ten chronic stroke subjects participated in eight 3-h sessions of RAVR therapy. Another group of nine stroke subjects participated in eight sessions of matched RTP therapy. Functional magnetic resonance imaging (fMRI data were acquired during paretic hand movement, before and after training. We compared the difference between groups and sessions (before and after training in terms of BOLD intensity, laterality index of activation in sensorimotor areas, and the effective connectivity between ipsilesional motor cortex (iMC, contralesional motor cortex, ipsilesional primary somatosensory cortex (iS1, ipsilesional ventral premotor area (iPMv, and ipsilesional supplementary motor area. Last, we analyzed the relationship between changes in fMRI data and functional improvement measured by the Jebsen Taylor Hand Function Test (JTHFT, in an attempt to identify how neurophysiological changes are related to motor improvement. Subjects in both groups demonstrated motor recovery after training, but fMRI data revealed RAVR-specific changes in neural reorganization patterns. First, BOLD

Neural Patterns of Reorganization after Intensive Robot-Assisted Virtual Reality Therapy and Repetitive Task Practice in Patients with Chronic Stroke.

Science.gov (United States)

Saleh, Soha; Fluet, Gerard; Qiu, Qinyin; Merians, Alma; Adamovich, Sergei V; Tunik, Eugene

2017-01-01

Several approaches to rehabilitation of the hand following a stroke have emerged over the last two decades. These treatments, including repetitive task practice (RTP), robotically assisted rehabilitation and virtual rehabilitation activities, produce improvements in hand function but have yet to reinstate function to pre-stroke levels-which likely depends on developing the therapies to impact cortical reorganization in a manner that favors or supports recovery. Understanding cortical reorganization that underlies the above interventions is therefore critical to inform how such therapies can be utilized and improved and is the focus of the current investigation. Specifically, we compare neural reorganization elicited in stroke patients participating in two interventions: a hybrid of robot-assisted virtual reality (RAVR) rehabilitation training and a program of RTP training. Ten chronic stroke subjects participated in eight 3-h sessions of RAVR therapy. Another group of nine stroke subjects participated in eight sessions of matched RTP therapy. Functional magnetic resonance imaging (fMRI) data were acquired during paretic hand movement, before and after training. We compared the difference between groups and sessions (before and after training) in terms of BOLD intensity, laterality index of activation in sensorimotor areas, and the effective connectivity between ipsilesional motor cortex (iMC), contralesional motor cortex, ipsilesional primary somatosensory cortex (iS1), ipsilesional ventral premotor area (iPMv), and ipsilesional supplementary motor area. Last, we analyzed the relationship between changes in fMRI data and functional improvement measured by the Jebsen Taylor Hand Function Test (JTHFT), in an attempt to identify how neurophysiological changes are related to motor improvement. Subjects in both groups demonstrated motor recovery after training, but fMRI data revealed RAVR-specific changes in neural reorganization patterns. First, BOLD signal in multiple

A Review of Policies, Acts and Initiatives in Rice Innovation System ...

African Journals Online (AJOL)

A review of rice policies, acts and initiatives in Nigeria is presented under ... World Bank, World Trade Organization, and International Monetary Fund (IMF) ... the desirable political will by government and sound agricultural rice policy are ...

[The new patient rights act : the significance for surgeons].

Science.gov (United States)

Dillschneider, J; Theuer, D; Mieth, M; Büchler, M W

2012-07-01

The committee draft for the new patient rights act was approved by the Federal Cabinet on 23 May 2012. Both the demands of the patient representative of the Federal government and some of the demands from the cornerstone paper of the State commission were taken into consideration.The draft of the new act contains comprehensive amendments to the Civil Code with the subtitle"Treatment contract in accordance with §630" and encompasses §§630a-h. The valid legal situation is therefore to all intents and purposes now codified.

Agreement between the Government of Canada and the Government of the Republic of Turkey for co-operation in the peaceful uses of nuclear energy

International Nuclear Information System (INIS)

1985-01-01

By Act No. 3258 of 11 February 1986 the Turkish National Assembly approved ratification of the Agreement of 18 June 1985 between the Government of Turkey and the Government of Canada for Co-operation in the Peaceful Uses of Nuclear Energy. The Agreement covers nuclear co-operation in industry agriculture, electricity generation, etc, and provides the legal framework for such co-operation. It lays down the general provisions for transfer of nuclear facilities, materials and technology between the two Parties and specifies the areas concerned. The Agreement provides that all the activities within its scope shall be carried out for exclusively peaceful purposes. (NEA) [fr

Australian Nuclear Science and Technology Organization Act 1987 - No 3 of 1987

International Nuclear Information System (INIS)

1987-01-01

The purpose of this Act (ANSTO Act) is to establish a successor to the Australian Atomic Energy Commission (AAEC) set up under the Atomic Energy Act 1953. The Act provides for a new Organization with functions which, according to Government policy, better reflect the directions in which Australia's principal research organization should tend in that area, namely realignment of AAEC activities away from work on the nuclear fuel cycle, towards greater emphasis on applications of radioisotopes and radiation in medicine, industry, agriculture, science, commerce, etc. ANSTO is prohibited from undertaking any R and D into the design and production of nuclear weapons or nuclear explosive devices. (NEA) [fr

45 CFR 73.735-901 - Reporting requirement of the Ethics in Government Act of 1978.

Science.gov (United States)

2010-10-01

... Government Ethics; (6) Department Ethics Counselor; and (7) Deputy Ethics Counselors. An employee who thinks... submit their reports to the reviewing official for their organizational component under procedures...

Downsizing and reorganization: demands, challenges and ambiguity for registered nurses.

Science.gov (United States)

Hertting, Anna; Nilsson, Kerstin; Theorell, Töres; Larsson, Ullabeth Sätterlund

2004-01-01

The 1990s were characterized by substantial financial cuts, and related staff redundancies and reorganizations in the Swedish health care sector. A large hospital in Sweden was selected for the study, in which downsizing had occurred between 1995 and 1997. The number of staff in the hospital was reduced by an average of 20%, and 10% were relocated to other departments. The aims of this study were to explore registered nurses' experiences of psychosocial 'stressors' and 'motivators', and how they handled their work situations, following a period of personnel reductions and ongoing reorganization. Interviews were undertaken with 14 nurses working in one Swedish hospital. Nurses were interviewed in 1997 about the recent and last round of redundancies, and were followed up 1 year later in 1998 and again in 2001. Interviews were audiotaped, transcribed and analysed for thematic content. Five themes emerged in relation to nurses' perceived stressors, motivators, and coping options: 'distrust towards the employer', 'concurrent demands and challenges', 'professional ambiguity, 'a wish for collaboration', and 'efforts to gain control'. A common feature was duality and ambiguity in nurses' descriptions of the phenomena studied, meaning that identified themes had underlying sub-themes with both negative and positive dimensions. The concurrence of 'ever-growing job demands' and 'work going unrewarded' contributed to a feeling of being taken advantage of by the employer. The 'waste of human resources' and 'competence drain' that followed redundancies provoked anger. Unfulfilled collaboration with doctors was a major stress producer, which related to both the downsized work organization, and the complex 'deference-dominance' doctor-nurse relationship. The well-being of nurses depends on being an equal/parallel health professional in a comprehensive team that shares knowledge and improves collaborative care of patients. A consciously formulated nursing philosophy emerged as a

The Davis-Bacon and Service Contract Acts: Laws Whose Time has Passed

National Research Council Canada - National Science Library

Pendolino, Timothy J

1994-01-01

In the Davis-Bacon and Service-Contract Acts, Congress attempted to protect the wages of workers in the construction and service industries by establishing a sort of minimum wage for Government contracts...

[A major game in the re-organization of the Professional Nursing School].

Science.gov (United States)

de Amorin, Wellington Mendonça; Barreira, Ieda de Alencar

2007-01-01

This is a historical-social description study supported on the thought of Pierre Bourdieu based on documental analysis. It describes the sanitarists and psychiatrists' actions from the reformulation of Education and Public Health Ministry into Education and Health Ministry in the beginning of New State and analyse the fight's strategies of the main agents to take advantage on their proposals of Professional Nursing School's reorganization. The fight's strategies that psychiatrists, sanitarists and certificated nurses had used to stake their projects, characterized a difficult battle inserted in a hard major game. The analyse of the ten course's months of the main document shows the conflict between those agents to impose a new rule to the school.

Reorganization of auditory map and pitch discrimination in adult rats chronically exposed to low-level ambient noise

Directory of Open Access Journals (Sweden)

Weimin eZheng

2012-09-01

Full Text Available Behavioral adaption to a changing environment is critical for an animal’s survival. How well the brain can modify its functional properties based on experience essentially defines the limits of behavioral adaptation. In adult animals the extent to which experience shapes brain function has not been fully explored. Moreover, the perceptual consequences of experience-induced changes in the brains of adults remain unknown. Here we show that the tonotopic map in the primary auditory cortex of adult rats living with low-level ambient noise underwent a dramatic reorganization. Behaviorally, chronic noise-exposure impaired fine, but not coarse pitch discrimination. When tested in a noisy environment, the noise-exposed rats performed as well as in a quiet environment whereas the control rats performed poorly. This suggests that noise-exposed animals had adapted to living in a noisy environment. Behavioral pattern analyses revealed that stress or distraction engendered by the noisy background could not account for the poor performance of the control rats in a noisy environment. A reorganized auditory map may therefore have served as the neural substrate for the consistent performance of the noise-exposed rats in a noisy environment.

Cytoskeleton reorganization/disorganization is a key feature of induced inaccessibility for defence to successive pathogen attacks.

Science.gov (United States)

Moral, Juan; Montilla-Bascón, Gracia; Canales, Francisco J; Rubiales, Diego; Prats, Elena

2017-06-01

In this work, we investigated the involvement of the long-term dynamics of cytoskeletal reorganization on the induced inaccessibility phenomenon by which cells that successfully defend against a previous fungal attack become highly resistant to subsequent attacks. This was performed on pea through double inoculation experiments using inappropriate (Blumeria graminis f. sp. avenae, Bga) and appropriate (Erysiphe pisi, Ep) powdery mildew fungi. Pea leaves previously inoculated with Bga showed a significant reduction of later Ep infection relative to leaves inoculated only with Ep, indicating that cells had developed induced inaccessibility. This reduction in Ep infection was higher when the time interval between Bga and Ep inoculation ranged between 18 and 24 h, although increased penetration resistance in co-infected cells was observed even with time intervals of 24 days between inoculations. Interestingly, this increase in resistance to Ep following successful defence to the inappropriate Bga was associated with an increase in actin microfilament density that reached a maximum at 18-24 h after Bga inoculation and very slowly decreased afterwards. The putative role of cytoskeleton reorganization/disorganization leading to inaccessibility is supported by the suppression of the induced resistance mediated by specific actin (cytochalasin D, latrunculin B) or general protein (cycloheximide) inhibitors. © 2016 BSPP AND JOHN WILEY & SONS LTD.

Crisis or not, renewable energy is hot. To reap the rewards, governments and companies should act now

International Nuclear Information System (INIS)

2009-03-01

2009 brings us new and difficult challenges. But it also offers real opportunities to change the course of our economies and the impact of the environmental footprint we will leave behind. As the European Union's 2020 environmental targets - 20% less CO2, 20% more energy efficiency, and an overall energy mix comprising 20% renewables - loom nearer, data suggests we are not yet on course to meet these ambitious targets. Despite the economic downturn, now is the time for action. The investments required in renewables could contribute to reverse the economic downtrend. To provide a sound basis for that action, PwC recently examined Europe's future renewable energy marketplace through the lens of progress towards the 2020 goals. This PwC study considers the market's potential, compares approaches in various countries, and puts forth some high-level recommendations for how governments and companies can reap the rewards. Making renewable energy 20% of total energy consumption in the 27 countries of the EU will require an investment of 1.8 to 7.3 trillion euros over the next decade depending on the type of renewable technology. In practical terms, that will mean building more than a million windmills or installing enough solar panels to cover an area twice the size of Belgium. A formidable challenge, no doubt. The opportunities, however, are proportionate to that challenge. The take-away from this study is really quite simple: The renewable market is set to become a major part of the energy sector - and the time to act is now

Impact of value chain governance on the development of small scale shrimp farmers in Vietnam

Directory of Open Access Journals (Sweden)

T. M. H. Ho

2016-06-01

Full Text Available Purpose of this paper is to identify the tendency of shrimp value chain development and impact of its governance on the small scale shrimp farmers in Vietnam. Design/methodology/approach - Data from the shrimp farmers surveys in Mekong delta, Vietnam from 2008-2010 with the update information in 2014 were taken to analyse by the value chain analysis method. Findings – Traditional governance type of the shrimp value chain in the early state (before 2004 showed the different levels of coordination of farmers with collectors, among collectors, and collectors with processing plants. In this type of governance, trust and linkages are inextricably linked. However, they are not strong. The processing plants determine shrimp prices and quality requirement in the market while many collectors do not seem to be highly responsible for the quality of their products. To avoid this limitation, with the governmental support policy to improve farmers’ income, the processing plants set up a direct buying from farmers under contracts. These contracts led to a new governance type with an expectation of improving farmers' position. However, this model was broken due to several reasons including un-controlled shrimp raw material from small scale and individual farmers. Consequently, processors now tend to establish their own raw material zone to comply shrimp quality assurance, and eject the existence of farmers. This will lead small scale farmers to very difficult problems in finding the market. Poverty and social problems of small scale farmers might appear. The result recommends a greater strengthening and tightening of the value chain. Re-organizing shrimp farmers into legal teams or groups that help farmers to re-participate in the game with others actor in the chain is crucial. Research limitations/implications - The research mainly follows inductive approach in w

ISSUES AND CHALLENGES IN WATER GOVERNANCE IN MALAYSIA

Directory of Open Access Journals (Sweden)

N. W. Chan

2009-07-01

Full Text Available Water is one of the central issues in the 21st century in Malaysia. Of all the issues associated with water management, governance is considered of primary importance. This paper examines water governance in Malaysia and concludes that it is successful in the sense that water is served to more than 95 % of the population, water tariffs are some of the cheapest in the world, the poor is not denied access, and water supply is 24 hours per day. However, there are many areas that need improvement to achieve better governance in water management. One is to improve Government-controlled water departments by ensuring their workers are well-trained and committed to excellence, public service and integrity instead of the usual laid-back government-servant mentality. Another is to ensure politicians do not interfere in the water sector. Currently, it is widely believed that many water companies are linked to powerful politicians, making the awarding of contracts, tariffs and other management aspects non-transparent and ineffective. Ideally, politicians that govern should act on the professional advice of the water managers and not the other way around. Another area of water governance that needs to be intensified is the war against corruption. In the water sector, there should also be an all-out war on corruption at all levels of governance, in both the public and private sectors. Government should make all contracts in the water sector awarded through open tender with public consultation to ensure professionalism, fairness, transparency, accountability and good governance. Equally, all contracts and other relevant documents drawn up between the government and private companies should not be “classified” but instead be public documents available to the public for discussion, review and improvement. Another area to ensure better governance is for the government to engage and actively involved all stakeholders in the water sector, especially civil

Benchmarking government action for obesity prevention--an innovative advocacy strategy.

Science.gov (United States)

Martin, J; Peeters, A; Honisett, S; Mavoa, H; Swinburn, B; de Silva-Sanigorski, A

2014-01-01

Successful obesity prevention will require a leading role for governments, but internationally they have been slow to act. League tables of benchmark indicators of action can be a valuable advocacy and evaluation tool. To develop a benchmarking tool for government action on obesity prevention, implement it across Australian jurisdictions and to publicly award the best and worst performers. A framework was developed which encompassed nine domains, reflecting best practice government action on obesity prevention: whole-of-government approaches; marketing restrictions; access to affordable, healthy food; school food and physical activity; food in public facilities; urban design and transport; leisure and local environments; health services, and; social marketing. A scoring system was used by non-government key informants to rate the performance of their government. National rankings were generated and the results were communicated to all Premiers/Chief Ministers, the media and the national obesity research and practice community. Evaluation of the initial tool in 2010 showed it to be feasible to implement and able to discriminate the better and worse performing governments. Evaluation of the rubric in 2011 confirmed this to be a robust and useful method. In relation to government action, the best performing governments were those with whole-of-government approaches, had extended common initiatives and demonstrated innovation and strong political will. This new benchmarking tool, the Obesity Action Award, has enabled identification of leading government action on obesity prevention and the key characteristics associated with their success. We recommend this tool for other multi-state/country comparisons. Copyright © 2013 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

E-Government Partnerships Across Levels of Government

OpenAIRE

Charbit, Claire; Michalun, Varinia

2009-01-01

E-government Partnerships across Levels of Government, is an overview of the challenges and approaches to creating a collaborative and cooperative partnership across levels of government for e-government development and implementation.

Angiotensin II induces reorganization of the actin cytoskeleton and myosin light-chain phosphorylation in podocytes through rho/ROCK-signaling pathway

NARCIS (Netherlands)

Wang, Siyuan; Chen, Cheng; Su, Ke; Zha, Dongqing; Liang, Wei; Hillebrands, J L; van Goor, Harry; Ding, Guohua

2016-01-01

Aims In the present study, we have evaluated the effect of angiotensin II (Ang II) on actin cytoskeleton reorganization and myosin light-chain (MLC) phosphorylation in podocytes to demonstrate whether the Rho/Rho-associated coiled kinase (ROCK) pathway is involved podocyte injury. Methods Eighteen

75 FR 33367 - Board of Governors; Sunshine Act Meeting

Science.gov (United States)

2010-06-11

... POSTAL SERVICE Board of Governors; Sunshine Act Meeting Times and Dates: 4 p.m., Monday, June 21... Broadway. Status: (Closed). Matters To Be Considered: Monday, June 21, at 4 p.m. (Closed) 1. Strategic...' Executive Session--Discussion of prior agenda items and Board Governance. Tuesday, June 22, at 10 a.m...

75 FR 63204 - Sunshine Act Meeting of the Board of Directors and Its Committees; Amended Notice; Changes to...

Science.gov (United States)

2010-10-14

... the Audit Committee. 14. Consider and act on the report of the Operations & Regulations Committee 15. Consider and act on the report of the Governance & Performance Review Committee. 16. Consider and act on..., 2010. Patricia D. Batie, Corporate Secretary. [FR Doc. 2010-26078 Filed 10-12-10; 4:15 pm] BILLING CODE...

Functional reorganization of motor and limbic circuits after exercise training in a rat model of bilateral parkinsonism.

Directory of Open Access Journals (Sweden)

Zhuo Wang

Full Text Available Exercise training is widely used for neurorehabilitation of Parkinson's disease (PD. However, little is known about the functional reorganization of the injured brain after long-term aerobic exercise. We examined the effects of 4 weeks of forced running wheel exercise in a rat model of dopaminergic deafferentation (bilateral, dorsal striatal 6-hydroxydopamine lesions. One week after training, cerebral perfusion was mapped during treadmill walking or at rest using [(14C]-iodoantipyrine autoradiography. Regional cerebral blood flow-related tissue radioactivity (rCBF was analyzed in three-dimensionally reconstructed brains by statistical parametric mapping. In non-exercised rats, lesions resulted in persistent motor deficits. Compared to sham-lesioned rats, lesioned rats showed altered functional brain activation during walking, including: 1. hypoactivation of the striatum and motor cortex; 2. hyperactivation of non-lesioned areas in the basal ganglia-thalamocortical circuit; 3. functional recruitment of the red nucleus, superior colliculus and somatosensory cortex; 4. hyperactivation of the ventrolateral thalamus, cerebellar vermis and deep nuclei, suggesting recruitment of the cerebellar-thalamocortical circuit; 5. hyperactivation of limbic areas (amygdala, hippocampus, ventral striatum, septum, raphe, insula. These findings show remarkable similarities to imaging findings reported in PD patients. Exercise progressively improved motor deficits in lesioned rats, while increasing activation in dorsal striatum and rostral secondary motor cortex, attenuating a hyperemia of the zona incerta and eliciting a functional reorganization of regions participating in the cerebellar-thalamocortical circuit. Both lesions and exercise increased activation in mesolimbic areas (amygdala, hippocampus, ventral striatum, laterodorsal tegmental n., ventral pallidum, as well as in related paralimbic regions (septum, raphe, insula. Exercise, but not lesioning, resulted

Functional Reorganization of Motor and Limbic Circuits after Exercise Training in a Rat Model of Bilateral Parkinsonism

Science.gov (United States)

Wang, Zhuo; Myers, Kalisa G.; Guo, Yumei; Ocampo, Marco A.; Pang, Raina D.; Jakowec, Michael W.; Holschneider, Daniel P.

2013-01-01

Exercise training is widely used for neurorehabilitation of Parkinson’s disease (PD). However, little is known about the functional reorganization of the injured brain after long-term aerobic exercise. We examined the effects of 4 weeks of forced running wheel exercise in a rat model of dopaminergic deafferentation (bilateral, dorsal striatal 6-hydroxydopamine lesions). One week after training, cerebral perfusion was mapped during treadmill walking or at rest using [14C]-iodoantipyrine autoradiography. Regional cerebral blood flow-related tissue radioactivity (rCBF) was analyzed in three-dimensionally reconstructed brains by statistical parametric mapping. In non-exercised rats, lesions resulted in persistent motor deficits. Compared to sham-lesioned rats, lesioned rats showed altered functional brain activation during walking, including: 1. hypoactivation of the striatum and motor cortex; 2. hyperactivation of non-lesioned areas in the basal ganglia-thalamocortical circuit; 3. functional recruitment of the red nucleus, superior colliculus and somatosensory cortex; 4. hyperactivation of the ventrolateral thalamus, cerebellar vermis and deep nuclei, suggesting recruitment of the cerebellar-thalamocortical circuit; 5. hyperactivation of limbic areas (amygdala, hippocampus, ventral striatum, septum, raphe, insula). These findings show remarkable similarities to imaging findings reported in PD patients. Exercise progressively improved motor deficits in lesioned rats, while increasing activation in dorsal striatum and rostral secondary motor cortex, attenuating a hyperemia of the zona incerta and eliciting a functional reorganization of regions participating in the cerebellar-thalamocortical circuit. Both lesions and exercise increased activation in mesolimbic areas (amygdala, hippocampus, ventral striatum, laterodorsal tegmental n., ventral pallidum), as well as in related paralimbic regions (septum, raphe, insula). Exercise, but not lesioning, resulted in decreases

The excitatory/inhibitory input to orexin/hypocretin neuron soma undergoes day/night reorganization.

Science.gov (United States)

Laperchia, Claudia; Imperatore, Roberta; Azeez, Idris A; Del Gallo, Federico; Bertini, Giuseppe; Grassi-Zucconi, Gigliola; Cristino, Luigia; Bentivoglio, Marina

2017-11-01

Orexin (OX)/hypocretin-containing neurons are main regulators of wakefulness stability, arousal, and energy homeostasis. Their activity varies in relation to the animal's behavioral state. We here tested whether such variation is subserved by synaptic plasticity phenomena in basal conditions. Mice were sacrificed during day or night, at times when sleep or wake, respectively, predominates, as assessed by electroencephalography in matched mice. Triple immunofluorescence was used to visualize OX-A perikarya and varicosities containing the vesicular glutamate transporter (VGluT)2 or the vesicular GABA transporter (VGAT) combined with synaptophysin (Syn) as a presynaptic marker. Appositions on OX-A + somata were quantitatively analyzed in pairs of sections in epifluorescence and confocal microscopy. The combined total number of glutamatergic (Syn + /VGluT2 + ) and GABAergic (Syn + /VGAT + ) varicosities apposed to OX-A somata was similar during day and night. However, glutamatergic varicosities were significantly more numerous at night, whereas GABAergic varicosities prevailed in the day. Triple immunofluorescence in confocal microscopy was employed to visualize synapse scaffold proteins as postsynaptic markers and confirmed the nighttime prevalence of VGluT2 + together with postsynaptic density protein 95 + excitatory contacts, and daytime prevalence of VGAT + together with gephyrin + inhibitory contacts, while also showing that they formed synapses on OX-A + cell bodies. The findings reveal a daily reorganization of axosomatic synapses in orexinergic neurons, with a switch from a prevalence of excitatory innervation at a time corresponding to wakefulness to a prevalence of inhibitory innervations in the antiphase, at a time corresponding to sleep. This reorganization could represent a key mechanism of plasticity of the orexinergic network in basal conditions.

Topological Reorganization of the Default Mode Network in Severe Male Obstructive Sleep Apnea

Directory of Open Access Journals (Sweden)

Liting Chen

2018-06-01

Full Text Available Impaired spontaneous regional activity and altered topology of the brain network have been observed in obstructive sleep apnea (OSA. However, the mechanisms of disrupted functional connectivity (FC and topological reorganization of the default mode network (DMN in patients with OSA remain largely unknown. We explored whether the FC is altered within the DMN and examined topological changes occur in the DMN in patients with OSA using a graph theory analysis of resting-state functional magnetic resonance imaging data and evaluated the relationship between neuroimaging measures and clinical variables. Resting-state data were obtained from 46 male patients with untreated severe OSA and 46 male good sleepers (GSs. We specifically selected 20 DMN subregions to construct the DMN architecture. The disrupted FC and topological properties of the DMN in patients with OSA were characterized using graph theory. The OSA group showed significantly decreased FC of the anterior–posterior DMN and within the posterior DMN, and also showed increased FC within the DMN. The DMN exhibited small-world topology in both OSA and GS groups. Compared to GSs, patients with OSA showed a decreased clustering coefficient (Cp and local efficiency, and decreased nodal centralities in the left posterior cingulate cortex and dorsal medial prefrontal cortex, and increased nodal centralities in the ventral medial prefrontal cortex and the right parahippocampal cortex. Finally, the abnormal DMN FC was significantly related to Cp, path length, global efficiency, and Montreal cognitive assessment score. OSA showed disrupted FC within the DMN, which may have contributed to the observed topological reorganization. These findings may provide further evidence of cognitive deficits in patients with OSA.

Mental health nursing and the problematic of supervision as a confessional act.

Science.gov (United States)

Banks, D; Clifton, A V; Purdy, M J; Crawshaw, P

2013-09-01

Mental health nurses frequently draw on self-disclosure practices within their working relationships. These 'confessional' acts can in turn be predicated on traditional assumptions of moral authority exercised by more senior colleagues. More broadly, attention has been drawn to the increasing significance of 'technologies of the self' inside neo-liberal regimes of governance. Through various forms of self-disclosure people are obliged 'to speak the truth about themselves'. By publically declaring themselves as 'fit for purpose' nurses are required to be reflexive, self-monitoring individuals, capable of constructing their own identities and biographies, and guided by expert knowledges. In this way, risk becomes a form of governance, as the individuals continually find themselves balancing risks and opportunities. Foucault's insights into the importance of 'care of the self' and 'surveillance of the self' to systems of social order and governance, such as mental health services, are significant in identifying nursing as a potential form of confessional practice. 'Reflective practice' and 'clinical supervision' are therefore 'technologies', functioning as 'modes of surveillance', and as 'confessional practices'. So 'clinical supervision' may be understood as part of a process of 'governance' that does not necessarily empower nurses, but can act to guide, correct and modify ways in which they conduct themselves. © 2012 John Wiley & Sons Ltd.

29 CFR 825.401 - Filing a complaint with the Federal Government.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Filing a complaint with the Federal Government. 825.401 Section 825.401 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Enforcement Mechanisms § 825.401 Filing a...

Should states and local governments regulate dietary supplements?

Science.gov (United States)

Starr, Ranjani

2016-01-01

Federal regulation of dietary supplements in the United States is governed by the Dietary Supplement Health and Education Act of 1994. The law has been criticized as weak and ineffective. Alarming research has emerged demonstrating that supplements may be mislabelled, contaminated, adulterated with dangerous or unknown compounds, or sold at toxic doses. As a result, the health community has raised concerns about the safety and quality of dietary supplements. Increased federal oversight is an important avenue for improving supplement safety; however, states and local governments may also pursue strategies to strengthen the overall regulatory control of dietary supplements. States and local governments have substantial experience in regulating other products that pose a risk to public health, such as tobacco. Additionally, much has been learned about the tactics the tobacco industry has employed to protect its interests. Lessons learned may be applied to new regulatory efforts aimed at improving the safety of dietary supplements at the state and local levels. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

Chapter 6: Working together in the federal government

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-07-01

In his review of the management of the environment and sustainable development within the federal government, the Commissioner stressed the importance of defining clearly of 'who does what' and identified a variety of mechanisms government departments have at their disposal to work together. These mechanisms range from the creation of new organizations to cost sharing agreements to voluntary networks for information exchange. Six case studies are described in detail designed to examine the key factors that could affect the success of such mechanisms. These factors include managing the effects of participant turnover, ensuring the continuity of departmental incentives, and paying attention to results of monitoring and evaluation to learn from past experience. It is suggested that since other than persuasion and negotiation, interdepartmental cooperation is limited by departments' inability to compel other departments to act, the primary central agencies, such as the Privy Council Office and the Treasury Board Secretariat must play a crucial leadership role in achieving a 'Government of Canada' perspective.

The Relationship Between Levels of Education and Perception of Democratic Governance Among Nigerian School Leavers

Directory of Open Access Journals (Sweden)

Adesoji A. ONI

2006-01-01

Full Text Available The study investigated the views and perception of school leavers about the democratic government in Nigeria. A self-designed questionnaire was used for collection of their views. The participants of the study comprised 500 school leavers selected across different working places in the six states of Southwest Nigeria. Results clearly revealed that majority of the respondents are not satisfied with the current performance of the present democratic Government in Nigeria. Most of the respondents suggested participation of everyone in the act of governance that favor rule of law, equality, and freedom and that this should be adopted by the government. The researcher therefore recommended a democratic system of government that will incorporate all the basic principles of democracy into the system of government, while marginalization and neglect of the poor, women, youth, and rural dwellers should be avoided.

A Critique of Pension Reform Act, 2004 In Nigeria

Directory of Open Access Journals (Sweden)

FRANCIS C. ANYIM

2014-08-01

Full Text Available Pension is benefit paid to an employee after attaining the statutory required age of retirement or if the employee leaves employment for other reasons. The benefit is meant to guarantee comfortable life after active years of service and also assist in the maintenance of living standard previously enjoyed during the beneficiaries’ active productive years. However, previous attempts by successive governments in Nigeria at instituting a hitch-free workable Pension Scheme have been hampered by inadequate and untimely funding, improper records, endemic fraud and corruption leading to avoidable pains and misery for the retirees and beneficiaries. It was on the account of these challenges in pension administration that the government of the Federal Republic of Nigeria, as part of its reform agenda established a new scheme referred to as Pension Reform Act, 2004. The study based on the qualitative research method and employing review of relevant literature takes a critical examination of the Act and concedes that although some inherent defects exist in the operations of the new Pension Scheme, these pitfalls are not fundamental or substantial to compromise or undermine the overall objectives of the Act. The paper therefore calls for an urgent review of some portions of the Pension Act, to check fraud, corruption and abuses currently inherent in the system. To treat these shortcomings with levity the paper contends may be tantamount to the State not playing its dutiful role in taking care of its senior citizens after active and meritorious years of service to the nation and fatherland.

Against acts of nuclear terrorism

International Nuclear Information System (INIS)

Heller, W.

2007-01-01

The Act on the International Convention of the United Nations of April 13, 2005 on Combating Acts of Nuclear Terrorism was promulgated in the German Federal Gazette and entered into force one day later. The Convention expresses the deep concern about the worldwide escalation of all kinds and manifestations of acts of terrorism. What was true in April 2005 (the year the UN convention was adopted) is even more true today. At the same time, however, the Convention recognizes the right of all nations to develop and use nuclear power for peaceful purposes, acknowledging their justified interest in the possible benefits of the peaceful uses of nuclear power. As the Convention was signed in German still during the term of office of the Red-Green government, this passage is a remarkable acceptance of the realities of the world and past peaceful uses of nuclear power in Germany. Whether or not the convention will become an effective instrument to be used against acts of nuclear terrorism and threats depends on its entering into force after deposition of 22 ratification documents, and on as many states as possible acceding to it. Irrespective of these aspects, action in the spirit of the Convention should be taken now, criminal law should be adapted, and international cooperation should be improved and strengthened. (orig.)

Using clinical governance levers to support change in a cancer care reform.

Science.gov (United States)

Brault, Isabelle; Denis, Jean-Louis; Sullivan, Terrence James

2015-01-01

Introducing change is a difficult issue facing all health care systems. The use of various clinical governance levers can facilitate change in health care systems. The purpose of this paper is to define clinical governance levers, and to illustrate their use in a large-scale transformation. The empirical analysis deals with the in-depth study of a specific case, which is the organizational model for Ontario's cancer sector. The authors used a qualitative research strategy and drew the data from three sources: semi-structured interviews, analysis of documents, and non-participative observations. From the results, the authors identified three phases and several steps in the reform of cancer services in this province. The authors conclude that a combination of clinical governance levers was used to transform the system. These levers operated at different levels of the system to meet the targeted objectives. To exercise clinical governance, managers need to acquire new competencies. Mobilizing clinical governance levers requires in-depth understanding of the role and scope of clinical governance levers. This study provides a better understanding of clinical governance levers. Clinical governance levers are used to implement an organizational environment that is conducive to developing clinical practice, as well as to act directly on practices to improve quality of care.

78 FR 27299 - Continuation of the National Emergency With Respect to the Actions of the Government of Syria

Science.gov (United States)

2013-05-09

... the National Emergency With Respect to the Actions of the Government of Syria #0; #0; #0; Presidential... National Emergency With Respect to the Actions of the Government of Syria On May 11, 2004, pursuant to his authority under the International Emergency Economic Powers Act, 50 U.S.C. 1701-1706, and the Syria...

75 FR 24777 - Continuation of the National Emergency With Respect To the Actions of the Government of Syria

Science.gov (United States)

2010-05-05

... to the Actions of the Government of Syria #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal... Actions of the Government of Syria On May 11, 2004, pursuant to his authority under the International Emergency Economic Powers Act, 50 U.S.C. 1701-1706, and the Syria Accountability and Lebanese Sovereignty...

76 FR 24791 - Continuation of the National Emergency With Respect to the Actions of the Government of Syria

Science.gov (United States)

2011-05-03

... National Emergency With Respect to the Actions of the Government of Syria On May 11, 2004, pursuant to his authority under the International Emergency Economic Powers Act, 50 U.S.C. 1701-1706, and the Syria... Government of Syria. To deal with this national emergency, Executive Order 13338 authorized the blocking of...

77 FR 27557 - Continuation of the National Emergency With Respect to the Actions of the Government of Syria

Science.gov (United States)

2012-05-10

... the National Emergency With Respect to the Actions of the Government of Syria #0; #0; #0; Presidential... National Emergency With Respect to the Actions of the Government of Syria On May 11, 2004, pursuant to his authority under the International Emergency Economic Powers Act, 50 U.S.C. 1701-1706, and the Syria...

Structural and functional reorganization of propriospinal connections promotes functional recovery after spinal cord injury

Directory of Open Access Journals (Sweden)

Linard Filli

2015-01-01

Full Text Available Axonal regeneration and fiber regrowth is limited in the adult central nervous system, but research over the last decades has revealed a high intrinsic capacity of brain and spinal cord circuits to adapt and reorganize after smaller injuries or denervation. Short-distance fiber growth and synaptic rewiring was found in cortex, brain stem and spinal cord and could be associated with restoration of sensorimotor functions that were impaired by the injury. Such processes of structural plasticity were initially observed in the corticospinal system following spinal cord injury or stroke, but recent studies showed an equally high potential for structural and functional reorganization in reticulospinal, rubrospinal or propriospinal projections. Here we review the lesion-induced plastic changes in the propriospinal pathways, and we argue that they represent a key mechanism triggering sensorimotor recovery upon incomplete spinal cord injury. The formation or strengthening of spinal detour pathways bypassing supraspinal commands around the lesion site to the denervated spinal cord were identified as prominent neural substrate inducing substantial motor recovery in different species from mice to primates. Indications for the existence of propriospinal bypasses were also found in humans after cortical stroke. It is mandatory for current research to dissect the biological mechanisms underlying spinal circuit remodeling and to investigate how these processes can be stimulated in an optimal way by therapeutic interventions (e.g., fiber-growth enhancing interventions, rehabilitation. This knowledge will clear the way for the development of novel strategies targeting the remarkable plastic potential of propriospinal circuits to maximize functional recovery after spinal cord injury.

What governs governance, and how does it evolve? The sociology of governance-in-action.

Science.gov (United States)

Fox, Nick J; Ward, Katie J

2008-09-01

Governance addresses a wide range of issues including social, economic and political continuity, security and integrity, individual and collective safety and the liberty and rights to self-actualization of citizens. Questions to be answered include how governance can be achieved and sustained within a social context imbued with cultural values and in which power is distributed unevenly and dynamically, and how governance impacts on individuals and institutions. Drawing on Gramscian notions of hegemony and consent, and recent political science literatures on regulation and meta-regulation, this paper develops a sociological model of governance that emphasizes a dynamic and responsive governance in action. Empirical data from a study of pharmaceutical governance is used to show how multiple institutions and actors are involved in sustaining effective governance. The model addresses issues of how governance is sustained in the face of change, why governance of practices varies from setting to setting, and how governance is achieved without legislation.

Healing arts radiation protection act: revised statutes of Ontario, 1980, chapter 195

International Nuclear Information System (INIS)

1990-09-01

An act published by the Government of Ontario by the Minister of Health to ensure public safety while subjected to the use of x-rays for the irradiation of human beings for therapeutic or diagnostic purposes

Guide to the Federal Act for Protection against Nuisances

International Nuclear Information System (INIS)

Thomas, J.; Wiedemann, R.

1980-07-01

The Federal Act for Protection against Nuisances contains all legal provisions related to pollution, noise, convulsions and shocks, thermal effects and similar effects on the environment. Apart from provisions of the actual Act for Protection against Nuisances, provisions related to nuisances are to be found in a number of legal fields. The authors provide a handy, completable survey on all relevant laws, ordinances, administrative regulations and directives issued by the Government of the federation and its individual states, and on the authorities responsible for their execution. The manual helps improve the transparency of legal provisions and adminstrative competences. (HSCH) [de

Air traffic security act unconstitutional; Luftsicherheitsgesetz verfassungswidrig

Energy Technology Data Exchange (ETDEWEB)

Heller, W.

2006-05-15

In the interest of more effective protective measures against terrorist attacks, the German federal parliament inter alia added a clause to the Air Traffic Security Act (Sec. 14, Para. 3, Air Traffic Security Act) empowering the armed forces to shoot down aircraft to be used as a weapon against human lives. In Germany, this defense possibility has been discussed also in connection with deliberate crashes of hijacked aircraft on nuclear power plants. The 1{sup st} Division of the German Federal Constitutional Court, in its decision of February 15, 2006, ruled that Sec. 14, Para. 3, Air Traffic Security Act was incompatible with the Basic Law and thus was null and void (file No. 1 BvR 357/05) for two reasons: - There was no legislative authority on the part of the federal government. - The provision was incompatible with the basic right of life and the guarantee of human dignity as enshrined in the Basic Law. (orig.)

Reorganization of the brain and heart rhythm during autogenic meditation.

Science.gov (United States)

Kim, Dae-Keun; Rhee, Jyoo-Hi; Kang, Seung Wan

2014-01-13

The underlying changes in heart coherence that are associated with reported EEG changes in response to meditation have been explored. We measured EEG and heart rate variability (HRV) before and during autogenic meditation. Fourteen subjects participated in the study. Heart coherence scores were significantly increased during meditation compared to the baseline. We found near significant decrease in high beta absolute power, increase in alpha relative power and significant increases in lower (alpha) and higher (above beta) band coherence during 3~min epochs of heart coherent meditation compared to 3~min epochs of heart non-coherence at baseline. The coherence and relative power increase in alpha band and absolute power decrease in high beta band could reflect relaxation state during the heart coherent meditation. The coherence increase in the higher (above beta) band could reflect cortico-cortical local integration and thereby affect cognitive reorganization, simultaneously with relaxation. Further research is still needed for a confirmation of heart coherence as a simple window for the meditative state.

Reorganization of the Brain and Heart Rhythm During Autogenic Meditation

Directory of Open Access Journals (Sweden)

Dae-Keun eKim

2014-01-01

Full Text Available The underlying changes in heart coherence that are associated with reported EEG changes in response to meditation have been explored. We measured EEG and heart rate variability (HRV before and during autogenic meditation. Fourteen subjects participated in the study. Heart coherence scores were significantly increased during meditation compared to the baseline. We found near significant decrease in high beta absolute power, increase in alpha relative power and significant increases in lower(alpha and higher(above beta band coherence during 3 minute epochs of heart coherent meditation compared to 3 minute epochs of heart noncoherence at baseline. The coherence and relative power increase in alpha band and absolute power decrease in high beta band could reflect relaxation state during the heart coherent meditation. The coherence increase in the higher(above beta band could reflect cortico-cortical local integration and thereby affect cognitive reorganization, simultaneously with relaxation. Further research is still needed for a confirmation of heart coherence as a simple window for the meditative state.

Cross-sectoral coordination for sustainable solutions in Croatia: The (meta) governance of energy efficiency

International Nuclear Information System (INIS)

Christopoulos, Stamatios; Demir, Cansu; Kull, Michael

2016-01-01

Increasing the energy efficiency not only requires the improvement of current technologies, but also advancement of and more coherent institutional governance. This paper captures the major structural and organisational elements of institutional governance in place for promoting energy efficiency. Looking at Croatia – one of the most successful cases of energy efficiency programming of the past decade – the paper zooms in on governance coordination (metagovernance) between actors from different sectors and operating at multiple levels. By showcasing the positive implications of the programme, the authors contribute to the debate concerned with identifying better institutional frameworks to attain sustainable development. The programme showed effective governance through vertical and horizontal coordination among institutions and stakeholders resulting in simultaneous social and economic development and improved energy efficiency in public buildings. Through the case of Croatia, this study identifies how metagovernance has supported coordination among actors aiming to create sustainable development in general and how metagovernance functions in energy efficiency related projects, in particular. The paper also sheds light on communication frameworks of governance coordination and institutional constraints lying at the heart of the vagueness of sustainable development. It also discusses private sector involvement to achieve better institutional framework to attain sustainable development. - Highlights: • This study identified how metagovernance has supported coordination among actors. • State played a key role in the coordination by acting as a catalyst. • UNDP acted as a mediator between government and society for capacity building. • Public authorities are less likely to continue activities without external support. • Private sector’s knowledge and resources are crucial to support project objectives.

Corporate debts ad credit performance under the new mechanism of reorganization of the Russian banks

Directory of Open Access Journals (Sweden)

Sergey A. Andryushin

2017-09-01

Full Text Available Objective to explore the dynamics and factors of formation of corporate debts the characteristics of low credit activity of the Russian banks and regulation of liquidity deficit of enterprises under the new reorganization mechanism in the Russian banking sector. Methods systematic approach to the cognition of economic phenomena which allows to study them in their dynamic development taking into account the influence of various environmental factors. The systematic approach determined selection of specific research methods empirical logical comparative and statistical. Results the article is devoted to the problems of declining credit activity of commercial banks under the conditions of economic activity revival as well as to assessing the impact of the new reorganization mechanism on this process. It is shown that in the recent years the nonfinancial sector faces the trend of optimizing the corporate debts and the liquidity deficit which reduced the demand for loans and as a consequence decreased the banksrsquo credit activity. To analyze the dynamics of deficitsurplus of liquidity in the corporate sector a new classification of liquidity deficitsurplus levels was introduced. Based on the proposed classification the risk factors were identified that influenced the dynamics of indebtedness in the corporate sector. The article also analyses the modern monetary mechanism of money supply in the economy and its transformation. It was determined that the main limitation of credit issuance by commercial banks is their capital not the reserve multiplier. The new mechanism of credit institutionsrsquo financial recovery and its impact on the banksrsquo credit activity was estimated. The conditions of liquidity deficiency reduction in the Russian companies were analyzed in the medium term. Scientific novelty for the first time on the basis of system analysis methods the growth factors of the corporate debt load were identified the peculiarities of low

The Animal Welfare Act and the zoo: A positive approach

Science.gov (United States)

Olsen, Glenn H.

1989-01-01

Interpretations of the Animal Welfare Act and other regulations governing use of research animals in the United States are changing. Recent amendments to the Act have resulted in the inclusion of more species under the umbrella of regulation. The role of the zoo and wildlife veterinarian should be that of leading his or her institution into a positive endorsement of these regulations and their application. Recent additions to the Code of Federal Regulations spell out the roles of the veterinarian and the Animal Care and Use Committee at an institution.

the dutch crisis and recovery act: economic recovery and legal crisis

African Journals Online (AJOL)

Jonathan

THE DUTCH CRISIS AND RECOVERY ACT: ECONOMIC RECOVERY AND. LEGAL CRISIS? J Verschuuren. 1 Introduction. Throughout the world, governments are responding to the financial and economic crisis. Such responses vary from supporting the banking system to adopting economic stimulus packages. The latter ...

A ROP2-RIC1 pathway fine-tunes microtubule reorganization for salt tolerance in Arabidopsis.

Science.gov (United States)

Li, Changjiang; Lu, Hanmei; Li, Wei; Yuan, Ming; Fu, Ying

2017-07-01

The reorganization of microtubules induced by salt stress is required for Arabidopsis survival under high salinity conditions. RIC1 is an effector of Rho-related GTPase from plants (ROPs) and a known microtubule-associated protein. In this study, we demonstrated that RIC1 expression decreased with long-term NaCl treatment, and ric1-1 seedlings exhibited a higher survival rate under salt stress. We found that RIC1 reduced the frequency of microtubule transition from shortening to growing status and knockout of RIC1 improved the reassembly of depolymerized microtubules caused by either oryzalin treatment or salt stress. Further investigation showed that constitutively active ROP2 promoted the reassembly of microtubules and the survival of seedlings under salt stress. A rop2-1 ric1-1 double mutant rescued the salt-sensitive phenotype of rop2-1, indicating that ROP2 functions in salt tolerance through RIC1. Although ROP2 did not regulate RIC1 expression upon salt stress, a quick but mild increase of ROP2 activity was induced, led to reduction of RIC1 on microtubules. Collectively, our study reveals an ROP2-RIC1 pathway that fine-tunes microtubule dynamics in response to salt stress in Arabidopsis. This finding not only reveals a new regulatory mechanism for microtubule reorganization under salt stress but also the importance of ROP signalling for salinity tolerance. © 2017 John Wiley & Sons Ltd.

78 FR 14278 - Privacy Act of 1974; System of Records

Science.gov (United States)

2013-03-05

... Logistics; Pub.L. 95-521, Ethics in Government Act; and DoD Directive 7050.5, Coordination of Remedies for Fraud and Corruption Related to Procurement Activities.'' Purpose(s): Delete entry and replace with... or group of individuals or other entities from DLA procurement and sales.'' Routine uses of records...

The influence of corporate governance on project governance

OpenAIRE

Gonda, Pavel

2011-01-01

This work identifies the interaction between corporate governance and project management in project governance. It begins with introduction of basics of corporate governance and various principles of corporate governance in chosen countries and organizations. Further it introduces theoretical background of project governance and its connection and to corporate governance. In practical part work analyzes the level of compliancy with Swiss codex of best praxis in chosen company. The results con...

The Role of Markets and Governments in Helping Society Adapt to a Changing Climate

International Nuclear Information System (INIS)

Mendelsohn, R.

2006-01-01

This paper provides an economic perspective of adaptation to climate change. The paper specifically examines the role of markets and government in efficient adaptation responses. For adaptations to be efficient, the benefits from following adaptations must exceed the costs. For private market goods, market actors will follow this principle in their own interest. For public goods, governments must take on this responsibility. Governments must also be careful to design institutions that encourage efficiency or they could inadvertently increase the damages from climate change. Finally, although in a few cases actors must anticipate climate changes far into the future, generally it is best to learn and then act with respect to adaptation

Permian-Triassic thermal anomaly of the active margin of South America as a result of plate kinematics reorganization

Science.gov (United States)

Riel, Nicolas; Jaillard, Etienne; Guillot, Stéphane; Martelat, Jean-Emmanuel; Braun, Jean

2013-04-01

From Permian to Triassic times, tectonic plate reorganization provoked Pangaea breakup, counterclockwise rotation of Gondwana, closing of the Paleo-Tethys Ocean and opening of the Neo-Tethys oceanic realm. Meanwhile, the switch from arc volcanism to widespread S-type magmatism along the western South American active margin around 275-265 Ma is symptomatic of the onset of a large-scale Permian-Triassic thermal anomaly (PTTA)affecting the whole margin. Here we report metamorphic and U-Pb geochronological results from the El Oro metamorphic complex in the forearc zone of southwestern Ecuador, which recorded the last step, at 230-225 Ma, of the PTTA. The change in the drift direction of Gondwana from north to east at ca. 270 Ma was related to plate reorganization and provoked the verticalization of the subducted Panthalassa slab. As the slab verticalized, strong heat advection produced a high heat flow beneath the active margin inducing the development of a huge thermal anomaly responsible for the PTTA, which lasted 30 Ma. This voluminous magmatic activity culminated at the Permian-Triassic boundary, and may have contributed to the degradation of life conditions on the Earth surface.

Engineering governance: introducing a governance meta framework.

OpenAIRE

Brand, N.; Beens, B.; Vuuregge, E.; Batenburg, R.

2011-01-01

There is a need for a framework that depicts strategic choices within an organisation with regard to potential governance structures. The governance meta framework provides the necessary structure in the current developments of governance. Performance as well as conformance are embedded in this framework and provide the balance for all governance domains. (aut.ref.)

Enhancing Physical Activity and Brain Reorganization after Stroke

Directory of Open Access Journals (Sweden)

Janet H. Carr

2011-01-01

Full Text Available It is becoming increasingly clear that, if reorganization of brain function is to be optimal after stroke, there needs to be a reorganisation of the methods used in physical rehabilitation and the time spent in specific task practice, strength and endurance training, and aerobic exercise. Frequency and intensity of rehabilitation need to be increased so that patients can gain the energy levels and vigour necessary for participation in physical activity both during rehabilitation and after discharge. It is evident that many patients are discharged from inpatient rehabilitation severely deconditioned, meaning that their energy levels are too low for active participation in daily life. Physicians, therapists, and nursing staff responsible for rehabilitation practice should address this issue not only during inpatient rehabilitation but also after discharge by promoting and supporting community-based exercise opportunities. During inpatient rehabilitation, group sessions should be frequent and need to include specific aerobic training. Physiotherapy must take advantage of the training aids available, including exercise equipment such as treadmills, and of new developments in computerised feedback systems, robotics, and electromechanical trainers. For illustrative purposes, this paper focuses on the role of physiotherapists, but the necessary changes in practice and in attitude will require cooperation from many others.

Serial functional imaging poststroke reveals visual cortex reorganization.

Science.gov (United States)

Brodtmann, Amy; Puce, Aina; Darby, David; Donnan, Geoffrey

2009-02-01

Visual cortical reorganization following injury remains poorly understood. The authors performed serial functional magnetic resonance imaging (fMRI) on patients with visual cortex infarction to evaluate early and late striate, ventral, and dorsal extrastriate cortical activation. Patients were studied with fMRI within 10 days and at 6 months. The authors used a high-level visual activation task designed to activate the ventral extrastriate cortex. These data were compared to those of age-appropriate healthy control participants. The results from 24 healthy control individuals (mean age 65.7 +/- SE 3.6 years, range 32-89) were compared to those from 5 stroke patients (mean age 73.8 +/- SE 7 years, range 49-86). Patients had infarcts involving the striate and ventral extrastriate cortex. Patient activation patterns were markedly different to controls. Bilateral striate and ventral extrastriate activation was reduced at both sessions, but dorsal extrastriate activated voxel counts remained comparable to controls. Conversely, mean percent magnetic resonance signal change increased in dorsal sites. These data provide strong evidence of bilateral poststroke functional depression of striate and ventral extrastriate cortices. Possible utilization or surrogacy of the dorsal visual system was demonstrated following stroke. This activity could provide a target for novel visual rehabilitation therapies.