The Globe laid bare

CERN Multimedia

Fortunati, Lucien

2015-01-01

If you’re at CERN at the moment, you will certainly have noticed the work under way on the Globe. The structure, which has been in pride of place opposite the Laboratory for over ten years, has never been so completely laid bare. But, as we explained in a previous article (see here), it is all for a good cause. The Globe is built entirely from wood and certain parts of it need to be replaced.

Teacher Preparation with GLOBE and NASA Assets

Science.gov (United States)

Czajkowski, K. P.; Templin, M.; Struble, J.; Mierzwiak, S.; Hedley, M. L.; Padgett, D.

2017-12-01

The GLOBE Program has been a working with teachers and students for over 20 years. Pre-service education students can be a target audience as well. Mission EARTH is a NASA funded project through the NASA Cooperative Agreement Notice (CAN) from the Science Mission Directorate. A goal of Mission EARTH is to improve student understanding of Earth System Science and to engage the next generation of scientists and global citizens. This presentation will discuss Weather and Climate courses offered at both the University of Toledo and Tennessee State University for pre-service education students. Students engaged in atmospheric observations through the GLOBE protocols and developed research projects to study El Nino. Undergraduate students helped K-12 students take GLOBE observations as well by partnering with in-service GLOBE teachers affiliated with these GLOBE partnerships.

The globe and orbit in Laron syndrome.

Science.gov (United States)

Kornreich, L; Konen, O; Lilos, P; Laron, Z

2011-09-01

Patients with LS have an inborn growth hormone resistance, resulting in failure to generate IGF-1. The purpose of this study was to evaluate the size of the eye and orbit in LS. We retrospectively reviewed the MR imaging of the brain in 9 patients with LS for the following parameters: axial diameter of the globe, interzygomatic distance, perpendicular distance from the interzygomatic line to margins of the globe, medial-to-lateral diameter of the orbit at the anterior orbital rim, distance from the anterior orbital rim to the anterior globe, maximal distance between the medial walls of the orbits, lateral orbital wall angle, lateral orbital wall length, and mediolateral thickness of the intraorbital fat in the most cranial image of the orbit. All measurements were made bilaterally. Twenty patients referred for MR imaging for unrelated reasons served as control subjects. Compared with the control group, the patients with LS had a significantly smaller maximal globe diameter and shallower but wider orbits due to a shorter lateral wall, a smaller medial distance between the orbits, and a larger angle of the orbit. The ratio between the most anterior orbital diameter and the globe was greater than that in controls. The position of the globe was more anterior in relation to the interzygomatic line. Shallow and wide orbits and small globes relative to orbital size are seen in LS and may be secondary to IGF-1 deficiency.

Children's drawings exhibited in the Globe

CERN Multimedia

Elizabeth Roe

2010-01-01

"Draw Me A Physicist" has been a success. Members of the public visiting the exhibition in the Globe of Science and Innovation have praised the scientific and creative balance the children of neighbouring France and the Canton of Geneva have obtained through their visit to CERN.   The Draw Me a Physicist exhibition in the Globe For a six-month period 9 to 11-year olds from the Pays de Gex, Meyrin, Satigny and Vernier have been able to enjoy a balance between science and art, through drawing and defining their interpretations of a physicist. In May, eight pairs of drawings from each participating class were selected by the schools to be displayed on the second floor of the Globe. Since the images have been put up, the viewers have enjoyed the contrast between the "before" pictures of vibrant Albert Einsteins to the "after" pictures of casual people sitting in an office. The large room in the Globe has been transformed from a hollow shell int...

[Conservative treatment of idiopathic scoliosis with physical therapy and orthoses].

Science.gov (United States)

Weiss, H-R

2003-02-01

Opinions differ in the international literature about the efficacy of conservative approaches to scoliosis treatment. Because this divergence of opinion corresponds to a great discrepancy in the standards applied to conservative treatment methods, it is not astonishing that the results of conservative treatment as described in the literature also differ. Scoliosis normally does not have such dramatic effects that immediate surgery would be indicated.Moreover, it is clear from the published literature that it is the functional and physiological impairments of scoliosis patients--including pain, torso deformity, psychological disturbance, and pulmonary dysfunction--which require therapeutic intervention. In Germany the triad of outpatient physiotherapy, intensive inpatient rehabilitation, and bracing has proven effective in conservative scoliosis treatment.Indication, content, and results of the individual treatment procedures are described and discussed. The positive outcomes of this practice validate a policy of offering conservative scoliosis treatment as an alternative to patients, including those for whom surgery is indicated.

Urban Utopias at the Globe

CERN Multimedia

2006-01-01

Since 19 May, the ground floor of the Globe has been housing a contemporary art exhibition. Meyrin's Contemporary Art Fund Committee has given six artists free rein to think up projects for the area surrounding the Globe, which is still a blank canvas. The exhibition entitled 'Urban Utopias', which explores the question 'How to experience the town?', consists of preparatory sketches and models of the works proposed by the artists. The projects on display include a metal ring symbolising the LHC accelerator, a statue consisting of pieces of broken wooden furniture, metal and bamboo, three metres in height, and even a projection of a computer-generated design for a ziggurat adjoining the Globe. Urban Utopias 19 May to 18 June, open Wednesday to Sunday from 2 p.m. to 6 p.m., Thursday until 9 p.m. Entrance free.

GLOBE-koolide õpilased assisteerivad NASA teadlasi / Imbi Henno

Index Scriptorium Estoniae

Henno, Imbi

2004-01-01

GLOBE (Global Learning and Observations to Benefit Environment) on õpilastele suunatud uurimuslikku ja praktilist tegevust pakkuv haridus- ja teadusprogramm. Õpilased teevad keskkonnavaatlusi ja mõõtmisi, saadavad oma tulemused interneti kaudu GLOBE'i andmebaasi ja kasutavad andmebaase koolitöös. Suvel toimus USA-s Boulderis GLOBE'i 10. tegevusaastale pühendatud konverents

Bilateral Traumatic Globe Luxation with Optic Nerve Transection

Directory of Open Access Journals (Sweden)

Levent Tok

2014-12-01

Full Text Available Purpose: The purpose of this study was to document clinical findings and management of a patient with bilateral globe luxation and optic nerve transection. Materials and Methods: A 25-year-old female patient was admitted to the emergency department with bilateral traumatic globe luxation following a motor vehicle accident. Results: Visual acuity testing showed no light perception. The right pupil was dilated and bilaterally did not react to light. The globes were bilaterally intact. A computed tomography scan revealed Le Fort type II fractures, bilateral optic nerve transection and disruption of all extraocular muscles. The globes of the patient were bilaterally reduced into the orbit. However, the patient developed phthisis bulbi in the right eye at month 3. Conclusion: Globe luxation presents a dramatic clinical picture, and may lead to the development of severe complications due to the concomitance of complete optic nerve dissection and multiple traumas. Even if the luxated globe is repositioned into the orbit, there is still an increased risk of the development of phthisis due to ischemia.

Bilateral Traumatic Globe Luxation with Optic Nerve Transection

Science.gov (United States)

Tok, Levent; Tok, Ozlem Yalcin; Argun, Tugba Cakmak; Yilmaz, Omer; Gunes, Alime; Unlu, Elif Nisa; Sezer, Sezgin; Ibisoglu, Seda; Argun, Mehmet

2014-01-01

Purpose The purpose of this study was to document clinical findings and management of a patient with bilateral globe luxation and optic nerve transection. Materials and Methods A 25-year-old female patient was admitted to the emergency department with bilateral traumatic globe luxation following a motor vehicle accident. Results Visual acuity testing showed no light perception. The right pupil was dilated and bilaterally did not react to light. The globes were bilaterally intact. A computed tomography scan revealed Le Fort type II fractures, bilateral optic nerve transection and disruption of all extraocular muscles. The globes of the patient were bilaterally reduced into the orbit. However, the patient developed phthisis bulbi in the right eye at month 3. Conclusion Globe luxation presents a dramatic clinical picture, and may lead to the development of severe complications due to the concomitance of complete optic nerve dissection and multiple traumas. Even if the luxated globe is repositioned into the orbit, there is still an increased risk of the development of phthisis due to ischemia. PMID:25606034

Conservative treatment and rehabilitation of shoulder problems

International Nuclear Information System (INIS)

Paternostro-Sluga, T.; Zoech, C.

2004-01-01

The shoulder joint has an important influence on arm- and handfunction. Therefore, activities of daily living, working and leisure time can be negatively influenced by diseases of the shoulder joint. Problems of the shoulder joint can be induced by muscular dysbalance and poor body posture. There is a strong relationship between shoulder function and body posture. Conservative treatment and rehabilitation of the shoulder joint aims at improving the local dysfunction of the shoulder joint as well as at improving function and social participation. Antiinflammatory and pain medication, exercise, occupational, electro-, ultrasound and shock wave therapy, massage, thermotherapy and pulsed electromagnetic fields are used as conservative treatments. Exercise therapy aims at improving muscular performance, joint mobility and body posture. Occupational therapy aims at improving functional movements for daily living and work. Electrotherapy is primarily used to relieve pain. Shock wave and ultrasound therapy proved to be an effective treatment for patients with calcific tendinitis. The subacromial impingement syndrome can be effectively treated by conservative therapy. (orig.) [de

The Globe of Innovation takes shape

CERN Multimedia

2004-01-01

On 18 May, the central vortex of the CERN Globe of Innovation was put into place more than 22 metres above the ground. The central vortex of the Globe of Innovation is a crown measuring 6.15 metres in diameter and 4.5 meters in height. Having been lifted by a crane to a height of over 22 metres, the vortex is placed on a support structure which will be removed once the 36 arcs providing the building's structure have been secured in place. Resting some 22 metres above the ground, the central vortex of the Globe of Innovation is now ready to support the 36 wooden arcs which will provide the building's structure. Work to reassemble the former Palais de l'Equilibre, which was first erected in Neuchâtel for the EXPO.02 exhibition, began on 18 May. The sphere, measuring 40 metres in diameter, has now been renamed the Globe of Innovation. A detachment from the Swiss army is carrying out the work, which will be completed in time for the Organization's official fiftieth anniversary celebrations. The building will be...

Conservative treatment of patellofemoral subluxation.

Science.gov (United States)

Henry, J H

1989-04-01

As pointed out in the preface of this book, patellofemoral subluxation is probably the most common knee problem seen in many orthopedists' offices today. Whereas the other authors have emphasized the anatomy and diagnosis, this article should serve as a dry but basic instruction on the exercise program that has been used in our clinic. We have had a success rate with this program of approximately 80 per cent. Certainly not all of the 20 per cent that fail require surgery. The classic exercises are quadricep sets, straight leg raises, hip abductors, hip adductors, hip flexors, and hamstring stretches, which have endured the test of time. The prevention of flexion extension activity, such as running the stadium stairs in order to strengthen the quadriceps of the patient with patellofemoral subluxation should be emphasized. Complications of conservative treatment, such as low back pain, iliopsoas tendinitis, and muscle soreness and the treatment of these is described. Finally, the importance of stretching the hamstring muscles is a cornerstone in the treatment of patellofemoral problems. Likewise, a tight IT band can put abnormal stress on the lateral aspect of the patella. In this article I have tried to point out our approach to conservative treatment of patellofemoral subluxation.

Orbital Blowout Fracture with Complete Dislocation of the Globe into the Maxillary Sinus.

Science.gov (United States)

Wang, Joy Mh; Fries, Fabian N; Hendrix, Philipp; Brinker, Titus; Loukas, Marios; Tubbs, R Shane

2017-09-29

This rare case report describes the diagnosis and treatment of an isolated left-sided orbital floor fracture with a complete dislocation of the globe into the maxillary sinus and briefly discusses the indications of surgery and recovery for orbital floor fractures in general. Complete herniation of the globe through an orbital blow-out fracture is uncommon. However, the current case illustrates that such an occurrence should be in the differential diagnosis and should be considered, especially following high speed/impact injuries involving a foreign object. In these rare cases, surgical intervention is required.

Green light for a permanent exhibition in the Globe

CERN Multimedia

2008-01-01

A donation to the Foundation for the Globe of Science and Innovation by ROLEX S.A. marks the first step towards the planned expansion of the Globe’s infrastructure. The Globe: a CERN emblem.Visible from miles away by day and by night, the Globe, the wooden sphere offered to CERN by the Swiss Confederation in 2004, has become one of the symbols of the Organization. Since being opened to the public in September 2005, the Globe has served as a venue for lectures, exhibitions, press and VIP events and workshops for schoolchildren and as a stage for theatre performances on scientific themes. With a view to turning the Globe into a flagship venue for events for the general public, and for interactions between CERN and its public and private partners, two projects are planned for the near future. CERN is receiving support for these ventures from the Foundation for the Globe. Established at the end of 2007, the Foundation’s mission is to ...

Linking the GLOBE Program With NASA and NSF Large-Scale Experiments

Science.gov (United States)

Filmer, P. E.

2005-12-01

NASA and the NSF, the sponsoring Federal agencies for the GLOBE Program, are seeking the participation of science teams who are working at the cutting edge of Earth systems science in large integrated Earth systems science programs. Connecting the GLOBE concept and structure with NASA and NSF's leading Earth systems science programs will give GLOBE schools and students access to top scientists, and expose them to programs that have been designated as scientific priorities. Students, teachers, parents, and their communities will be able to see how scientists of many disciplines work together to learn about the Earth system. The GLOBE solicitation released by the NSF targets partnerships between GLOBE and NSF/NASA-funded integrated Earth systems science programs. This presentation will focus on the goals and requirements of the NSF solicitation. Proponents will be expected to provide ways for the GLOBE community to interact with a group of scientists from their science programs as part of a wider joint Earth systems science educational strategy (the sponsoring agencies', GLOBE's, and the proposing programs'). Teams proposing to this solicitation must demonstrate: - A focus on direct connections with major NSF Geosciences and/or Polar Programs and/or NASA Earth-Sun research programs that are related to Earth systems science; - A demonstrable benefit to GLOBE and to NSF Geosciences and/or Polar Programs or NASA Earth-Sun education goals (providing access to program researchers and data, working with GLOBE in setting up campaigns where possible, using tested GLOBE or non-GLOBE protocols to the greatest extent possible, actively participating in the wider GLOBE community including schools, among other goals); - An international component; - How the existing educational efforts of the large science program will coordinate with GLOBE; - An Earth systems science education focus, rather than a GLOBE protocol-support focus; - A rigorous evaluation and assessment component

A New Look for the Globe Gardens

CERN Multimedia

Katarina Anthony

2010-01-01

Designs to develop the grounds of the Globe of Science and Innovation have recently been unveiled. The plan is to extend the visitor activities on offer, transforming the area into a public arena for scientific exploration.   Design for the new Globe Gardens. © Jencks Squared and Groupe H. After months of conceptual development, plans to develop the site around the Globe are taking shape. The innovative designs were drawn up for CERN by a unique collaboration consisting of landscape architects Charles and Lily Jencks, and "Groupe H", a group of architects headed by Globe designer Hervé Dessimoz. They comprise new venues, covered walkways, a café and gift shop, a separate VIP entrance and a physics-inspired garden for visitors. The landscape itself becomes a feature – dramatically altered to create a cosmic garden formed by shaped mounds, ponds, and a natural amphitheatre for public events. “The new exhibition in the G...

Friday Programme for CineGlobe 2015

CERN Multimedia

Marcelloni De Oliveira, Claudia

2015-01-01

Workshops, apero with filmmakers and short-films inspired by science were the menu of the festival through the day. At night the CineGlobe DOME shown with the 360 degree projections shot-films; among them the avant-premiere of "Phantom of the Universe" - a movie that explains Dark Matter, directed by Joao Pequenao. Meanwhile at the Globe, the audience could enjoy the projections of the sequence of " The Invisible Photograph" .

Adhesions small bowel obstruction in emergency setting: conservative or operative treatment?

Science.gov (United States)

Assenza, M; De Gruttola, I; Rossi, D; Castaldi, S; Falaschi, F; Giuliano, G

2016-01-01

Adhesions small bowel obstructions (aSBO) are among the leading causes of emergency operative intervention. About the 80% of aSBO cases resolve without a surgical treatment. It's important to identify which patients could undergo a conservative treatment to prevent an useless surgery The aim of this study is to determine findings that can indicate whether patients with aSBO should undergo a conservative or a surgical treatment. 313 patients with diagnosis of submission of aSBO were restudied. Patients were divided into two groups based on the different type of treatment received, 225 patients who underwent surgical treatment within 24 hours after admission, 88 patients which underwent conservative treatment successfully. For each patient, clinical, hematochemical and radiological findings have been analysed. The treatment of aSBO should be, at the beginning, conservative except that cases that presents clinical and/or CT-scan findings predictive for a surgical treatment (free peritoneal fluid, mesenterial edema, transitional point) or a peritonitis (pneumatosis intestinalis, pneumoperitoneum).

Presenting CineGlobe Estival! | 6 - 10 July

CERN Multimedia

2016-01-01

Join CineGlobe under a projected starry sky for a film festival and games with a neuroscience twist.   The 6th edition of the CineGlobe International Film Festival at CERN will take place during the first week of July 2016 (on the Globe grounds at CERN, from Wednesday 6 to Friday 8 July) and then during the Nuit de la Science (at the Museum of the History of Science, on July 9 and 10). The festival will include an open-air cinema, film projections in the Globe of Science and Innovation at CERN, the interactive Emotional Circus (carnival-inspired games played with just the participant’s brainwaves) and a special sci-fi edition of the 48 Hour Film Project. The full program will target people of all ages with fun and informative activities such as children’s films in the Minima Cinema, and a workshop on the creation of a pinhole camera with an empty Tetra-Pak milk carton. Practical information: Entry is free. All films in English and French. Onsite food trucks at the G...

Conservation irradiation in the treatment of breast cancer

International Nuclear Information System (INIS)

Faria, S.L.; Chiminazzo Junior, H.

1985-01-01

Techniques of treatment and cosmetic results of 130 patients with breast cancer are presented. All patients received conservative treatment, with lumpectomy and radiotherapy at Centro de Oncologia Campinas. (M.A.C.) [pt

Spontaneous globe luxation associated with chronic obstructive pulmonary disease

Directory of Open Access Journals (Sweden)

M Ashok Kumar

2012-01-01

Full Text Available Spontaneous globe luxation is a rarely reported condition which can lead to complications like optic neuropathy. Common causes are thyroid eye disease, shallow orbit and floppy eyelid syndrome. We report a case of spontaneous globe luxation with the onset and severity associated with chronic obstructive pulmonary disease (COPD. To our knowledge, this is the first case of spontaneous globe luxation associated with COPD.

GLOBE-al Impact through Diversity Bootcamps and Student Research Symposia

Science.gov (United States)

Bourgeault, J.; Murphy, T.; Johnson, J.; Sparrow, E. B.; Czajkowski, K. P.; Herron, S.; Falcon, P.

2016-12-01

Inclusion, diversity, underrepresented groups, underserved populations...the key words and phrases that represent the students, we, as science education professionals, want to reach and encourage to enter the geoscience pipeline. Wanting to do this is one thing and having the skills to succeed is very different. It is also one that the GLOBE Program, an international science and education program, is working on as a community. GLOBE encourages students from around the world to participate in authentic scientific research of the Earth system. Students use scientific protocols to explore their local environments, compare their findings with other GLOBE schools both in the U.S. and in other participating countries, and then share their findings via the GLOBE.gov website. In the last year, two initiatives, six face-to-face Student Research Symposia and two diversity-focused GLOBE Partner Bootcamps, set the GLOBE community of Partners, teachers and students on the path to being able to address this challenge. This presentation will include the framework for the student research symposia, the barriers the leadership team faced when recruiting and getting students there and the lessons learned. Agendas for the GLOBE Partner Bootcamps will be shared to demonstrate how facilitators supplemented a standard GLOBE Partner workshop to model a more inclusive environment, along with future improvements to the format.

The Globe opens its doors to the public

CERN Multimedia

2005-01-01

The Globe of Science and Innovation has quickly become the most recognisable landmark on the CERN skyline. Since construction was completed last summer, the Globe's distinctive spherical shape has greeted and intrigued visitors and employees on arrival at CERN.

Globes and Teaching Aids Manufactured by Jan Felkl Company for the Polish Market

Directory of Open Access Journals (Sweden)

Malgorzata Taborska

2016-05-01

Full Text Available Jan Felkl company from Roztoky (Roztok near Prague manufactured globes in seventeen language versions, since 1861 also in Polish language. The company was active until 1952, but it ceased to manufacture Polish-language globes as early as in 1914. In the aftermath of the First World War, and with the development of printing business, the demand for Czech globes shrank. It is difficult to estimate the overall output of Polish- language globes manufactured by Felkl’s company throughout the 53 years it operated. From catalogues and the surviving globes we know that terrestrial globes in six sizes, folding globes in two sizes, celestial globes (probably in four sizes, as well as telluria, lunaria and planetaria were manufactured for the Polish market. It is difficult to decide how many editions of individual types of globes were issued. Polish names were compiled by Franciszek Waligórski (one globe and Mirosław Suchecki. Only 28 globes have survived to this day, including one celestial globe. Most of them are globes of an 8-inch diameter, approved by the Austrian ministries as teaching aids for schools. Nearly half of the surviving globes date from the years 1894–1914. Only ten items are in museums.

Occupational open globe injuries.

Science.gov (United States)

Vasu, U; Vasnaik, A; Battu, R R; Kurian, M; George, S

2001-03-01

Occupational ocular trauma is an important cause of acquired monocular blindness in a rapidly industrialising country like India. Knowledge of the epidemiology of occupational eye injuries is essential to formulate viable industrial safety measures. We retrospectively reviewed all patients with occupational open globe injuries between 1994 and 1998. We documented the circumstances of the injuries, their clinical findings and the use of appropriate protective eyewear at the time of the injury. The visual acuity 6 months after the injury was the final outcome measure. In this study period we examined 43 patients with open globe injuries sustained at the work place. Thirty-four (79.1%) patients were young males. The iron and steel industry accounted for 19 (44.2%) cases while 8 (18.6%) patients each were from the agricultural, mining and other small scale industrial sectors. At the time of the injury, 33 (76.7%) were not wearing the recommended protective eyewear and 6 (13.9%) were under the influence of alcohol. The injuries were mild in 6 (13.9%), moderate in 18 (41.9%) and severe in 19 (44.2%) patients. At the end of 6 months, 2 (4.7%) patients had a visual acuity of 6/12 or better, 4 (9.3%) had a visual acuity of 6/18 to 6/60 and 29 (67.4.%) had a vision of eyewear and alcohol-free environment at the work place is likely to reduce the incidence of severe occupational open globe injuries.

Tool or Toy? Virtual Globes in Landscape Planning

Directory of Open Access Journals (Sweden)

Stephen R. J. Sheppard

2011-10-01

Full Text Available Virtual globes, i.e., geobrowsers that integrate multi-scale and temporal data from various sources and are based on a globe metaphor, have developed into serious tools that practitioners and various stakeholders in landscape and community planning have started using. Although these tools originate from Geographic Information Systems (GIS, they have become a different, potentially interactive and public tool set, with their own specific limitations and new opportunities. Expectations regarding their utility as planning and community engagement tools are high, but are tempered by both technical limitations and ethical issues [1,2]. Two grassroots campaigns and a collaborative visioning process, the Kimberley Climate Adaptation Project case study (British Columbia, illustrate and broaden our understanding of the potential benefits and limitations associated with the use of virtual globes in participatory planning initiatives. Based on observations, questionnaires and in-depth interviews with stakeholders and community members using an interactive 3D model of regional climate change vulnerabilities, potential impacts, and possible adaptation and mitigation scenarios in Kimberley, the benefits and limitations of virtual globes as a tool for participatory landscape planning are discussed. The findings suggest that virtual globes can facilitate access to geospatial information, raise awareness, and provide a more representative virtual landscape than static visualizations. However, landscape is not equally representative at all scales, and not all types of users seem to benefit equally from the tool. The risks of misinterpretation can be managed by integrating the application and interpretation of virtual globes into face-to-face planning processes.

[Perinatal result with conservative treatment in preeclampsia-eclampsia].

Science.gov (United States)

Briones-Garduño, Jesús Carlos; de León-Ponce, Manuel Díaz; González-Vargas, Angel; Briones-Vega, Carlos Gabriel

2003-01-01

Conservative treatment in severe preeclampsia has been documented by several authors citing significant improvement in neonatal outcome lacking a significant increase in maternal complications. Our objective was to inform of our preliminary results using protocolized conservative management in women with preeclampsia-eclampsia, favoring better neonate conditions. We included 34 patients with average age of 28.2 years with documented severe preeclampsia-eclampsia complicating a 36-weeks or less pregnancy, admitted in the obstetric intensive care unit (OICU) between October 2001 and February 2002. Patients received protocolized management consisting of intravascular colume expansion, anti-hypertensive control, target organ protection, monitoring, and clinical observation. We considered conservative management as a 24 or more period offered to patients with satisfactory response to medical treatment and no evidence of binomial compromise. Of our group, 85% corresponded to severe preeclampsia, 9% to eclampsia, 3% to imminence of eclampsia, and 3% to HELLP syndrome. Average stay in OICU was 5.5 days with 3.5 days average management before pregnancy was interrupted. These patients presented mean gestational age of 32.8 weeks during which we observed anemia, low platelets, D dimmer increments, MAP average of 112.8, PCOc 18.6, and BI 0.15. We obtained 36 live newborns of whom 12% four died, two were extremely immatures (510 g and 600 g, respectively); one 980-g newborn presented intraventricular hemorrhage, and a 1,450-g newborn had multiple organ failure. Conservative treatment in patients with severe preeclampsia-eclampsia is a feasible alternative in hospitals with an ICU. Conservative management can improve neonatal survival and prognosis in preterm newborns.

The conservative treatment of the breast cancer

International Nuclear Information System (INIS)

Souhami, L.

1982-01-01

Despite major achievements in the medical field, the survival rate of patients with breast cancer has not changed over the last 50 years. Certain treatments once taken as definitive are now being reviewed. The therapeutic evolution of breast cancer is studied and emphasis is given to new treatment modalities, particularly the conservative ones. (Author) [pt

Exhibition at CERN's Globe of Science and Innovation

CERN Multimedia

Claudia Marcelloni

2006-01-01

Here we see pictures of displays at one of the exhibitions held at the Globe of Science and Innovation taken in September 2006. Located opposite the main CERN site, the Globe houses many public exhibitions throughout the year covering many topics from astronomy to particle physics.

7 CFR 631.7 - Conservation treatment eligible for cost sharing.

Science.gov (United States)

2010-01-01

..., conservation practices, or identifiable units eligible for GPCP cost sharing in the state. (b) The designated... conservation systems, practices, or identifiable units eligible for GPCP cost sharing in the county. ... 7 Agriculture 6 2010-01-01 2010-01-01 false Conservation treatment eligible for cost sharing. 631...

[Conservative treatment of deciduous teeth--a review].

Science.gov (United States)

Magnusson, B

1976-06-01

In all countries with a lack of manpower in dentistry, there is an unfortunate tendency to leave the primary teeth without proper conservative treatment. In addition to toothaches and poor esthetics, a neglected care of the primary dentition may result in several other untoward effects. Decayed deciduous teeth may cause such a discomfort during tooth-brushing that the child is prevented from learning good oral hygiene habits. With bad primary molars the child cannot chew properly, and may have to choose soft and often cariogenic food. When the permanent teeth erupt among the decayed deciduous teeth, there will be a greater chance for them to have carious attacks as well. Premature loss of primary molars may lead to malocclusion. It must also be kept in mind that the treatment of badly decayed teeth, including necessary extractions, may be difficult. This may cause fear of dental treatment. On the basis of current Swedish philosophies of treatment the author surveys various conservative procedures for deciduous teeth-amalgam therapy, stainless steel crowns, composites and disking.

The relationship of the globe to the orbital rim.

Science.gov (United States)

Eckstein, Lauren A; Shadpour, Joseph M; Menghani, Ravi; Goldberg, Robert A

2011-01-01

To present a novel method for accurately characterizing the position of the globe relative to the orbital rim. The appearance and function of the eyelids are dependent on the underlying orbital bony architecture and globe position; however, no comprehensive language to describe these complex 3-dimensional relationships exists. Three-dimensional orbital reconstructions were generated from computed tomographic scans of 15 Occidental and 12 Oriental orbits without orbital pathologic disease. Globe and orbital rim anatomy were identified and outlined. Reference points were measured along 2 independent axes: (1) the distance between a plane defined by the corneal apex and the sagittal projection of the orbital rim and (2) the distance between the circumference of the globe and the coronal projection of the orbital rim. For Occidental orbits, the mean (SD) elevation of the sagittal projection of the orbital rim relative to the anterior projection of the globe was 4.6 (4.2) mm superiorly, 5.9 (3.0) mm nasally, 12.6 (3.7) mm inferiorly, and 20.6 (2.6) mm laterally. The mean (SD) radial distance between the coronal projection of the orbital rim and the circumference of the globe was 3.7 (2.1) mm superiorly, 7.6 (1.8) mm nasally, 6.6 (2.2) mm inferiorly, and 4.6 (2.3) mm laterally. For Oriental orbits, the mean (SD) elevation of the sagittal projection of the orbital rim relative to the anterior projection of the globe was 5.0 (4.5) mm superiorly, 6.8 (4.1) mm nasally, 11.1 (4.3) mm inferiorly, and 17.5 (3.3) mm laterally. The mean (SD) radial distance between the coronal projection of the orbital rim and the circumference of the globe was 2.1 (1.2) mm superiorly, 8.2 (2.0) mm nasally, 6.5 (1.9) mm inferiorly, and 4.5 (1.7) mm laterally. Comparison of Occidental and Oriental orbital rim and globe configurations revealed quantitative and qualitative differences. In addition to differences in soft-tissue anatomy, bony architectural variations may contribute substantially to

Place-based Learning About Climate with Elementary GLOBE

Science.gov (United States)

Hatheway, B.; Gardiner, L. S.; Harte, T.; Stanitski, D.; Taylor, J.

2017-12-01

Place-based education - helping students make connections between themselves, their community, and their local environment - is an important tool to help young learners understand their regional climate and start to learn about climate and environmental change. Elementary GLOBE storybooks and learning activities allow opportunities for place-based education instructional strategies about climate. In particular, two modules in the Elementary GLOBE unit - Seasons and Climate - provide opportunities for students to explore their local climate and environment. The storybooks and activities also make connections to other parts of elementary curriculum, such as arts, geography, and math. Over the long term, place-based education can also encourage students to be stewards of their local environment. A strong sense of place may help students to see themselves as stakeholders in their community and its resilience. In places that are particularly vulnerable to the impacts of climate and environmental change and the economic, social, and environmental tradeoffs of community decisions, helping young students developing a sense of place and to see the connection between Earth science, local community, and their lives can have a lasting impact on how a community evolves for decades to come. Elementary GLOBE was designed to help elementary teachers (i.e., grades K-4) integrate Earth system science topics into their curriculum as they teach literacy skills to students. This suite of instructional materials includes seven modules. Each module contains a science-based storybook and learning activities that support the science content addressed in the storybooks. Elementary GLOBE modules feature air quality, climate, clouds, Earth system, seasons, soil, and water. New eBooks allow students to read stories on computers or tablets, with the option of listening to each story with an audio recording. A new Elementary GLOBE Teacher Implementation Guide, published in 2017, provides

Using the GLOBE Program To Enhance Classroom Teaching.

Science.gov (United States)

Ramey, Linda K.; Tomlin, James

The Wright State University Global Learning and Observations to Benefit the Environment (GLOBE) Franchise has developed a project to fill the need for direct, strong connections linking science, mathematics and technology to classroom curriculum and students' learning of integrated, relevant content. GLOBE is an international project that involves…

Locally Motivated GLOBE Investigations - A Key to Success

Science.gov (United States)

Washburne, J. C.; Geery, W.

2003-12-01

The GLOBE program was set up to help students make a core set of environmental observations at or near their schools, report their data through the internet to share with other students and scientists, analyze their data both locally and globally, and use this knowledge to form a better understanding of their environment. While the GLOBE program has been successful promoting more meaningful data collection, many of the tools and much of the infrastructure available to schools to synthesize their observations are underused. Schools that integrate GLOBE protocols with locally motivated investigations are more likely to implement the higher-order analysis and synthesis components of the program. Indicators of a successful observational program are things like measurement persistence, high data quality, and regular data. Participation in community forums and student-based research projects are evidence of a successful integrated program. A locally motivated issue allows a school to mold their GLOBE investigations around a multi-faceted question that they have first-hand knowledge of, that is both relevant and engaging to their students, and that can be supported by local expertise. In contrast, many GLOBE investigations are designed around abstract, non-site specific, narrowly focused and externally analyzed questions that limit local involvement and motivation. The main focus of this presentation is a few case histories of successful local investigations that incorporated GLOBE soil and air temperature data-logger measurements. The main example is drawn from Mr. Geery's fifth grade class investigation of why temperature differences exist between a local river bottom area and the school, which is located several kilometers away and 100 meters higher.

A new mural for the Globe

CERN Multimedia

Laëtitia Pedroso

2010-01-01

A 53 metre long and 6 metre high mural has graced the ramp of the Globe since 21 June. Containing life-size photos of the CMS experiment and an event in the ATLAS detector, its visual impact cannot fail to rouse visitors' curiosity.   The new mural installed in the Globe Visitors ascending from the ground-floor to the first floor of the Globe are now greeted by a huge visual record of what's going on below ground at CERN and is no longer accessible on guided tours of the Laboratory. "The mural contains full-scale photos that give you a real feel of how the CMS detector is constructed and of the degree of precision of the particle tracks in the ATLAS event", explains Rolf Landua, Head of the Education Group, who came up with the project in conjunction with Bernard Pellequer. Several people were instrumental in bringing the project to life. The collage of 250 photographs of the CMS detector was retouched and assembled by Maximilien Brice, CERN's photographer, with the assistance o...

Global Land One-kilometer Base Elevation (GLOBE) v.1

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — GLOBE is a project to develop the best available 30-arc-second (nominally 1 kilometer) global digital elevation data set. This version of GLOBE contains data from 11...

VRPI Temporal Progression of Closed Globe Injury from Blast Exposure

Science.gov (United States)

2015-09-01

significant increases in VEGF have been reported in many ocular disorders including diabetic retinopathy , diffuse macular edema, retinal vein...Open globe injury is often readily identifiable and typically undergoes urgent surgical repair. However, closed globe injury may not be detected ...including shrapnel or debris to the eye, is easily identified and rapidly treated. Closed globe trauma may not be detected right away, and little is

[Extensive conservative treatment of obesity].

Science.gov (United States)

Buri, Caroline; Laederach, Kurt

2013-02-01

The treatment of obesity is complex due to the multifactorial etiology. A modern therapy concept must therefore be tailored to the individual needs and problems and depends on various factors such as degree of obesity, the presence of physical complications, psychological co-morbidities, any treatment measures the patient underwent up to now as well as on motivational factors. Before deciding on a therapeutic measure a structured multidisciplinary cooperation is essential including psychosomatic medicine/psychiatry/psychotherapy, endocrinology, sports medicine, nutritional medicine and surgery as well. The treatment must be carried out in a multidisciplinary team and includes an adequate therapy of comorbidities and sometimes a psychopharmacological support. The success of a conservative treatment of obesity is remarkable and long-lasting and can be straightforwardly compared to bariatric surgery in financial as well as ethical terms, although for patients and their physicians the latter often carries the allure of quick success.

Science Outreach in Virtual Globes; Best Practices

Science.gov (United States)

Treves, R. W.

2007-12-01

The popularity of projects such as 'Crisis in Darfur' and the IPY (International Polar Year) network link show the potential of using the rich functionality of Virtual Globes for science outreach purposes. However, the structure of outreach projects in Virtual Globes varies widely. Consider an analogy: If you pick up a science journal you immediately know where to find the contents page and what the title and cover story are meant to communicate. That is because journals have a well defined set of norms that they follow in terms of layout and design. Currently, science projects presented in virtual globes have, at best, weakly defined norms, there are little common structural elements beyond those imposed by the constraints of the virtual globe system. This is not a criticism of the science community, it is to be expected since norms take time to develop for any new technology. An example of the development of norms are pages on the web: when they first started appearing structure was unguided but over the last few years structural elements such as a left hand side navigation system and a bread crumb trail near the header have become common. In this paper I shall describe the developing norms of structure I have observed in one area of virtual globe development; Google Earth science outreach projects. These norms include text introductions, video introductions, use of folders and overlay presentation. I shall go on to examine how best to use these norms to build a clear and engaging outreach project and describe some cartographic best practices that we should also consider adopting as norms. I also will briefly explain why I think norms in science outreach aid creativity rather than limiting it despite the counter intuitive nature of this concept.

Stress -induced biosynthesis of dicaffeoylquinic acids in globe artichoke

NARCIS (Netherlands)

Moglia, A.; Lanteri, S.; Comino, C.; Acquadro, A.; Vos, de C.H.; Beekwilder, M.J.

2008-01-01

Leaf extracts from globe artichoke (Cynara cardunculus L. var. scolymus) have been widely used in medicine as hepatoprotectant and choleretic agents. Globe artichoke leaves represent a natural source of phenolic acids with dicaffeoylquinic acids, such as cynarin (1,3-dicaffeoylquinic acid), along

Niche Specialization and Conservation Biology of Cicindela Nevadica Lincolniana

Science.gov (United States)

Brosius, Tierney R.

2010-01-01

As with many organisms across the globe, "Cicindela nevadica lincolniana" is threatened with extinction. Understanding ecological factors that contribute to extinction vulnerability and what methods aid in the recovery of those species is essential in developing successful conservation programs. Here we examine behavioral mechanisms for niche…

Lagochilascariasis leading to severe involvement of ocular globes, ears and meninges.

Science.gov (United States)

Aquino, Renata T R; Magliari, Maria E R; Vital Filho, José; Silva, Maria A L G; Lima, Carlos A da Conceição; Rocha, Antonio J; Silva, Carlos J; Rewin, Jonathan A; Nahas, Tatiana R; Chieffi, Pedro Paulo

2008-01-01

A case report of a 31 year-old woman from Paraíba State (North-Eastern Brazil) that presented severe involvement of ocular globes, ears and meninges. Diagnosis was established after enucleation of her left eye, when adult worms were seen in the midst of a granulomatous inflammatory process. Her response to the initial treatment with levamisole and cambendazole was good, but there was a relapse after the fifth month of treatment even with maintenance doses of both medications. She later received ivermectin and albendazol and responded well.

Second conservative radiosurgical treatment for ipsilateral breast cancer recurrence

International Nuclear Information System (INIS)

Castelli, J.; Courdi, A.; Hannoun-Levi, J.M.; Figl, A.; Raoust, I.; Lallement, M.; Flipo, B.; Ettore, F.; Chapelier, C.; Ferrero, J.M.

2011-01-01

Purpose. - Currently, radical mastectomy represents the gold standard for ipsilateral breast cancer recurrence. However, we already showed that a second conservative treatment was feasible combining lumpectomy plus low-dose rate interstitial brachytherapy. In this study, we reported the preliminary results of a second conservative treatment using a high-dose rate brachytherapy. Patients and methods. - From June 2005 to July 2009, 42 patients presenting with an ipsilateral breast cancer recurrence underwent a second conservative treatment. Plastic tubes were implanted intraoperatively at the time of the lumpectomy. After a post-implant CT scan, a total dose of 34 Gy in 10 fractions over 5 consecutive days was delivered through an ambulatory procedure. The toxicity evaluation used the Common Terminology Criteria for Adverse Events v3.0. Results. - The median follow-up was 21 months (6-50 months), median age at the time of the local recurrence was 65 years (30-85 years). The median delay between the primary and the recurrence was 11 years (1-35 years). The location of the recurrence was in the tumor bed for 22 patients (52.4%), in the same quadrant for 14 patients (33.3%) and unknown for six patients (14.3%). The median tumor size of the recurrence was 12 mm (2-30 mm). The median number of plastic tubes and plans were nine (5-12) and two (1-3) respectively. The median CTV was 68 cm 3 (31.2-146 cm 3 ). The rate of second local control was 97%. Twenty-two patients (60%) experienced complications. The most frequent side effect consisted in cutaneous and sub-cutaneous fibrosis (72% of all the observed complications). Conclusion. - A second conservative treatment for ipsilateral breast cancer recurrence using high-dose rate brachytherapy appears feasible leading to encouraging results in terms of second local control with an acceptable toxicity. Considering that a non-inferiority randomized trial comparing mastectomy versus second conservative treatment could be difficult

Virtual Globes, where we were, are and will be

Science.gov (United States)

Dehn, J.; Webley, P. W.; Worden, A. K.

2016-12-01

Ten years ago, Google Earth was new, and the first "Virtual Globes" session was held at AGU. Only a few of us realized the potential of this technology at the time, but the idea quickly caught on. At that time a virtual globe came in two flavors, first a complex GIS system that was utterly impenetrable for the public, or a more accessible version with limited functionality and layers that was available on a desktop computer with a good internet connection. Google Earth's use of the Keyhole Markup Language opened the door for scientists and the public to share data and visualizations across disciplines and revolutionized how everyone uses geographic data. In the following 10 years, KML became more advanced, virtual globes moved to mobile and handheld platforms, and the Google Earth engine allowed for more complex data sharing among scientists. Virtual globe images went from a rare commodity to being everywhere in our lives, from weather forecasts, in our cars, on our smart-phones and shape how we receive and process data. This is a fantastic tool for education and with newer technologies can reach the the remote corners of the world and developing countries. New and emerging technologies allow for augmented reality to be merged with the globes, and for real-time data integration with sensors built into mobile devices or add-ons. This presentation will follow the history of virtual globes in the geosciences, show how robust technologies can be used in the field and classroom today, and make some suggestions for the future.

Kyphoplasty vs conservative treatment: a case-control study in 110 post-menopausal women population. Is kyphoplasty better than conservative treatment?

Science.gov (United States)

Colangelo, D; Nasto, L A; Genitiempo, M; Formica, V M; Autore, G; Pambianco, V; Tamburrelli, F C; Cerulli, G; Pola, E

2015-11-01

Osteoporosis is a highly prevalent disease worldwide. Consequences of vertebral osteoporotic fractures include pain and progressive vertebral collapse resulting in spinal kyphosis, decreased quality of life, disability and mortality. Minimally invasive procedures represent an advance to the treatment of osteoporotic VCFs. Despite encouraging results reported by many authors, surgical intervention in an osteoporotic spine is fraught with difficulties. Advanced patients age and comorbidities are of great concern. We designed a retrospective case-control study on 110 post-menopausal women consecutively visited at our institution. Study population was split in a surgical and a conservative cohort, according to the provided treatment. Kyphoplasty treated patients had lower back pain VAS scores at 1 month as compared with conservatively treated patients (p < 0.05). EQ5D validated questionnaire also showed a better quality of life at 1 month for surgically treated patients (p < 0.05). SF-12 scores showed greater improvements at 1 month and 3 months with statistically significant difference between the two groups just at 3 months (p < 0.05). At 12 months, scores from all scales were not statistically different between the two cohorts, although surgically treated patients showed better trends than conservatively treated patients in pain and quality of life. Kyphoplasty was able to restore more than 54.55% of the original segmental kyphosis, whereas patients in conservative cohort lost 6.67% of the original segmental kyphosis on average. Kyphoplasty is a modern minimal invasive surgery, allowing faster recovery than bracing treatment. It can avoid the deformity in kyphosis due to VCF. In fact, the risk to develop a new vertebral fracture after the first one is very high.

Conservative treatment of bronchobiliary fistula evaluated with magnetic resonance imaging

Directory of Open Access Journals (Sweden)

Adžić-Vukičević Tatjana N.

2015-01-01

Full Text Available Introduction. Bronchobiliary fistula (BBF is a pathological communication between the bronchial system and the biliary tree that presents with bilioptysis. Many conditions can cause its development. There is still no optimal therapy for BBF. Conservative treatment is rarely indicated, as was published before in a few cases. Case report. We presented a 71-year-old Caucasian Serbian woman with BBF secondary to previous laparotomy due to multiple echinococcus liver cysts. The diagnosis was established by the presence of bilirubin and bile acids in sputum and magnetic resonance cholangiopancreatography (MRCP. A repeat MRCP performed after conservative procedure, did not reveal fistulous communication. Conclusion. We suggest that in small and less severe fistulas between the biliary and the bronchial tract, conservative treatment may be used successfully, and invasive treatment methods are not needed in all patients.

Surgery or conservative treatment for rotator cuff tear: a meta-analysis.

Science.gov (United States)

Ryösä, Anssi; Laimi, Katri; Äärimaa, Ville; Lehtimäki, Kaisa; Kukkonen, Juha; Saltychev, Mikhail

2017-07-01

Comparative evidence on treating rotator cuff tear is inconclusive. The objective of this review was to evaluate the evidence on effectiveness of tendon repair in reducing pain and improving function of the shoulder when compared with conservative treatment of symptomatic rotator cuff tear. Search on CENTRAL, MEDLINE, EMBASE, CINAHL, Web of Science and Pedro databases. Randomised controlled trials (RCT) comparing surgery and conservative treatment of rotator cuff tear. Study selection and extraction based on the Cochrane Handbook for Systematic reviews of Interventions. Random effects meta-analysis. Three identified RCTs involved 252 participants (123 cases and 129 controls). The risk of bias was considered low for all three RCTs. For Constant score, statistically insignificant effect size was 5.6 (95% CI -0.41 to 11.62) points in 1-year follow up favouring surgery and below the level of minimal clinically important difference. The respective difference in pain reduction was -0.93 (95% CI -1.65 to -0.21) cm on a 0-10 pain visual analogue scale favouring surgery. The difference was statistically significant (p = 0.012) in 1-year follow up but below the level of minimal clinically important difference. There is limited evidence that surgery is not more effective in treating rotator cuff tear than conservative treatment alone. Thus, a conservative approach is advocated as the initial treatment modality. Implications for Rehabilitation There is limited evidence that surgery is not more effective in treating rotator cuff tear than conservative treatment alone. There was no clinically significant difference between surgery and active physiotherapy in 1-year follow-up in improving Constant score or reducing pain caused by rotator cuff tear. As physiotherapy is less proneness to complications and less expensive than surgery, a conservative approach is advocated as the initial treatment modality to rotator cuff tears.

Unfolding Leonardo DA Vinci's Globe (ad 1504) to Reveal its Historical World Map

Science.gov (United States)

Verhoeven, G. J.; Missinne, S. J.

2017-08-01

This paper reports in detail on the image-based modelling and unwrapping approach used to create a two-dimensional projected map of an astonishing ostrich egg globe from AD 1504. This miniature egg globe is not only the oldest extant engraved globe, but it is also the oldest post-Columbian globe of the world and the first ever to depict Newfoundland and many other territories. The intention of digitally recording the surface geometry and colour of this unique artefact was to portray the original layout of the world map used by the Florentine Renaissance artist to make this globe. In addition, it was expected to substantiate iconographical details, which are hard to study at its scale of 1:80,000,000. The ostrich egg globe is the prototype of the Lenox Globe kept at the New York Public Library. The latter is very beneficial to examine how the egg globe looked like before being glued together at its equator. On the other hand, unfolding the map engraved in the ostrich egg halves enables a more detailed study of the remarkable details visible on both globes, since the engravings on the quasi-white egg surface are much easier to discern than those of the highly reflective red copper Lenox Globe. Finally, a detailed study of the unwrapped 3D surface is essential to learn more about the world vision of its creator and the incredible efforts that went into making this globe. Thanks to some particular pictographic details as well as the way in which the engravings are applied (by a left-handed person), the globe artist can be identified as Leonardo da Vinci.

"Big Science: the LHC in Pictures" in the Globe

CERN Multimedia

2008-01-01

An exhibition of spectacular photographs of the LHC and its experiments is about to open in the Globe. The LHC and its four experiments are not only huge in size but also uniquely beautiful, as the exhibition "Big Science: the LHC in Pictures" in the Globe of Science and Innovation will show. The exhibition features around thirty spectacular photographs measuring 4.5 metres high and 2.5 metres wide. These giant pictures reflecting the immense scale of the LHC and the mysteries of the Universe it is designed to uncover fill the Globe with shape and colour. The exhibition, which will open on 4 March, is divided into six different themes: CERN, the LHC and the four experiments ATLAS, LHCb, CMS and ALICE. Facts about all these subjects will be available at information points and in an explanatory booklet accompanying the exhibition (which visitors will be able to buy if they wish to take it home with them). Globe of Science and Innovatio...

Conservative treatment of acute appendicitis: an overview

NARCIS (Netherlands)

Wojciechowicz, K. H.; Hoffkamp, H. J.; van Hulst, R. A.

2010-01-01

Background. Although the standard treatment for appendicitis (since 1883) is an appendectomy, this is not always possible in a maritime or military setting. To avoid relying on improvisation in such situations this study examines the evidence for conservative management of appendicitis. Material and

And the winner of the Golden CinéGlobe is…

CERN Multimedia

Laëtitia Pedroso

2010-01-01

Three years after the first CinéGlobe festival, the CERN film club has just organised a second international festival of short films and science documentaries, attended by a host of film-makers and film fans alike. Six special prizes were awarded.   One of the Golden CinéGlobe awards The second Golden CinéGlobe award ceremony was held in the Globe on the evening of Saturday, 20 February. Now something of a magnet for local fans of short films and science documentaries, the CinéGlobe festival has become one of the most successful events organised by a CERN club. "Organising the festival has been a gratifying experience as many people have taken part in and enjoyed the event", says Quentin King, vice-chairman of the CERN film club, Open Your Eyes Films. "Time was our worst enemy. It took us a year to bring the project to fruition but we could have done with another year to refine some of the details". The 18 screenings...

Case studies in residual use and energy conservation at wastewater treatment plants

Energy Technology Data Exchange (ETDEWEB)

Stewart, D. [Science Applications International Corp., Los Altos, CA (United States)

1995-06-01

The US Environmental Protection Agency (EPA) and the National Renewable Energy Laboratory (NREL) for the US Department of Energy (DOE) funded a study to document energy conservation activities and their effects on operation costs, regulatory compliance, and process optimization at several wastewater treatment plants (WWTPS). The purpose of this report is to review the efforts of wastewater treatment Facilities that use residuals as fuels. Case histories are presented for facilities that have taken measures to reduce energy consumption during wastewater treatment. Most of the WWTPs discussed in this report have retrofitted existing facilities to achieve energy conservation. The case studies of energy conservation measures found no effects on the facilities` ability to comply with NPDES permits. Indeed, energy conservation activities enhance environmental compliance in several ways.

Seeing Stars: A GLOBE at Night Campaign Update

Science.gov (United States)

Walker, Constance E.; Pompea, S. M.; Sparks, R. T.; Newhouse, M.

2012-01-01

The emphasis in the international citizen-science, star-hunting campaign, GLOBE at Night, is in bringing awareness to the public on issues of light pollution. Light pollution threatens not only observatory sites and our "right to starlight", but can affect energy consumption, wildlife and health. GLOBE at Night has successfully reached a few 100,000 citizen-scientists. What has done in the last year to contribute to its success? • To promote the campaign via popular social media, GLOBE at Night created Facebook and Twitter pages. • Videos have been created for 4 out of 8 Dark Skies Rangers activities. • Sky brightness measurements can be submitted in real time with smart phones or tablets using the new Web application at www.globeatnight.org/webapp/. The location, date and time register automatically. • As a proto-type, an adopt-a-street program had people in Tucson take measurements every mile for the length of the street. Grid measurements canvassed the town, allowing for comparisons of light levels over time. • The increase to 2 campaigns in 2011 re-enforces these studies. In 2012, the campaign will be offered 4 times for 10 days a month: January 14-23, February 12-21, March 13-22 and April 11-20. • A new Web application (www.globeatnight.org/mapapp/) allows for mapping GLOBE at Night data points within a specified distance around a city or area of choice. The resulting maps are bookmarkable and shareable. • NOAO and Arizona Game and Fish Department started a project with GLOBE at Night data and bat telemetry to examine a dark skies corridor in Tucson where endangered bats fly. While providing these updates to the GLOBE at Night program, the presentation will highlight the education and outreach value of the program's resources and outcomes, lessons learned, successes and pitfalls in communicating awareness with the public and attracting young people to study science.

GLOBE Cornerstones: Advancing Student Research Worldwide through Virtual and Regional Symposia

Science.gov (United States)

Bourgeault, J.; Malmberg, J. S.; Murphy, T.; Darche, S.; Ruscher, P.; Jabot, M.; Odell, M. R. L.; Kennedy, T.

2016-12-01

The GLOBE Program, an international science and education program, encourages students from around the world to participate in authentic scientific research of the Earth system. Students use scientific protocols to explore their local environments, compare their findings with other GLOBE schools both in the U.S. and in other participating countries, and then share their findings via the GLOBE.gov website. In order to facilitate this scientific communication, GLOBE held an international virtual science fair in 2016. The science fair included 105 research projects submitted from GLOBE students in various countries, 37 mentoring scientists, and 24 judges. Mentors and judges were members of the GLOBE International STEM Professionals Network and located around the world. On a national level, NSF funded six face-to-face U.S. regional student research symposia where 164 students presented 67 research projects to scientists for review. The 1.5 day events included student activities, teacher professional development, tours of NASA centers, and opportunities for students to engage with scientists to discover both traditional and non-traditional STEM career pathways. To support teachers, the leadership team offered and archived webinars on science practices; from field investigation basics to creating a poster and GLOBE partners provided guidance along the way. This presentation will include the framework for the regional and international science symposia , the scoring rubrics and evaluation, recruitment of judges and mentors, and lessons learned.

Eye globe abnormalities on MR and CT in adults: An anatomical approach

International Nuclear Information System (INIS)

Hallinan, James Thomas Patrick Decourcy; Pillay, Premilla; Koh, Lilian Hui; Goh, Kong Yong; Yu, Wai Yung

2016-01-01

Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highlighted using case examples with fundoscopic correlation where appropriate. In the emergent setting, trauma can result in hemorrhage, retinal/choroidal detachment and globe rupture. Neoplasms and inflammatory/infective processes predominantly occur in the vascular middle layer. The radiologist has an important role in primary diagnosis contributing to appropriate ophthalmology referral, thereby preventing devastating consequences such as vision loss

Eye globe abnormalities on MR and CT in adults: An anatomical approach

Energy Technology Data Exchange (ETDEWEB)

Hallinan, James Thomas Patrick Decourcy; Pillay, Premilla [Dept. of Diagnostic Imaging, National University Health System, Singapore (Singapore); Koh, Lilian Hui [National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Level 1, TTSH Medical Centre, Singapore (Singapore); Goh, Kong Yong [Yong Loo Lin School of Medicine, National University of Singapore, Singapore (Singapore); Yu, Wai Yung [Dept. of Neuroradiology, National Neuroscience Institute, Singapore (Singapore)

2016-09-15

Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highlighted using case examples with fundoscopic correlation where appropriate. In the emergent setting, trauma can result in hemorrhage, retinal/choroidal detachment and globe rupture. Neoplasms and inflammatory/infective processes predominantly occur in the vascular middle layer. The radiologist has an important role in primary diagnosis contributing to appropriate ophthalmology referral, thereby preventing devastating consequences such as vision loss.

Eye Globe Abnormalities on MR and CT in Adults: An Anatomical Approach

Energy Technology Data Exchange (ETDEWEB)

Hallinan, James Thomas Patrick Decourcy; Pillay, Premilla [Department of Diagnostic Imaging, National University Health System, Singapore 119074 (Singapore); Koh, Lilian Hui Li [National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Level 1, TTSH Medical Centre, Singapore 308433 (Singapore); Goh, Kong Yong [Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597 (Singapore); Dr. Goh Eye Neuro-Ophthalmic and Low Vision Specialist, Mount Elizabeth Novena Specialist Centre, Singapore 329563 (Singapore); Yu, Wai-Yung [Department of Neuroradiology, National Neuroscience Institute, Singapore 308433 (Singapore)

2016-11-01

Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highlighted using case examples with fundoscopic correlation where appropriate. In the emergent setting, trauma can result in hemorrhage, retinal/choroidal detachment and globe rupture. Neoplasms and inflammatory/infective processes predominantly occur in the vascular middle layer. The radiologist has an important role in primary diagnosis contributing to appropriate ophthalmology referral, thereby preventing devastating consequences such as vision loss.

Open globe injury with an interesting intra-ocular foreign body

Directory of Open Access Journals (Sweden)

Gill, Ekjyot

2017-07-01

Full Text Available Introduction: Cases of penetrating ocular trauma due to osseous material are limited, so reported incidents are valuable in determining outcomes and proper treatment courses.Case description: We report a case of an open globe injury of the left eye with an intraocular foreign body occurring after a firework exploded in the hand of a 22-year-old man. The patient presented with light perception vision in the injured eye with a full-thickness limbal laceration and dense hyphema obscuring fundoscopy. CT scan revealed a hyperdense foreign body juxtaposed to the lens. Immediate surgical intervention to repair the globe rupture revealed a defect in the anterior capsule and small, white objects in the posterior chamber that were promptly removed. Pathologic investigation determined these fragments to be cortical bone likely from the patient’s phalanges. Results and discussion: There was no evidence of endophthalmitis or keratitis from time of injury to the five-month follow-up, suggesting that the risk of infection may be low and therefore it may be reasonable to manage these injuries with a period of observation.

GLOBE Aerosol Field Campaign - U.S. Pilot Study 2016

Science.gov (United States)

Pippin, Margaret; Marentette, Christina; Bujosa, Robert; Taylor, Jessica; Lewis, Preston

2016-01-01

During the spring of 2016, from April 4 - May 27, sixteen GLOBE schools participated in the GLOBE Aerosol Field Campaign - U.S. Pilot Study. Thirteen teachers from these schools had previously participated in the NASA LEARN program (Long-term Experience in Authentic Research with NASA) where they were GLOBE trained in Atmosphere protocols, and engaged in 1-3 years of research under the mentorship of NASA scientists. Each school was loaned two aerosol instruments for the Campaign duration, either 2 GLOBE sun photometers, 2 Calitoo sun photometers, or 1 of each. This allowed for students to make measurements side-by-side and in the case of the Calitoos, to compare AOT results immediately with each other for better consistency in data collection. Additionally, as part of the Field Campaign evaluation, multiple instruments allow for an assessment of the ease of use of each instrument for grade level of students, whether in middle school or high school. Before the Campaign, all GLOBE and Calitoo instruments were 'checked out' against an AERONET, then checked again upon return after the Campaign. By examining all data, before, during and after the Campaign, this gives an indication of instrument performance and proficiency obtained by the students. Support was provided to each teacher and their students at the level requested, via email, phone or video conferencing.

CinéGlobe invites you to participate in a poster design competition

CERN Multimedia

Neal David Hartman

2013-01-01

For its 2014 publicity campaign, CinéGlobe invites CERN people to participate in a poster design competition.  The entries are now on display on the Pas Perdus in the main building, and the CERNois are invited to vote for their favourites.    CinéGlobe is the international festival of short films inspired by science that takes place every two years at CERN, in the Globe of Science and Innovation. From 18 to 23 March 2014, CERN will host the fourth edition of the festival. The mission of the CinéGlobe Film Festival is to challenge the commonly perceived divisions between science and art by demonstrating that they are both essential to interpreting our world. Open to short film creators from around the world, the CinéGlobe festival is truly international, the first three editions having attracted more than 4,000 entries from more than 100 countries around the globe.  In addition to screening...

[Conservative treatment of hyperthyroidism (author's transl)].

Science.gov (United States)

Schumm, P M; Usadel, K H; Schulz, F; Schumann, J; Schöffling, K

1981-01-09

Antithyroid medication was given to 158 patients with hyperthyroidism over a period of 3 to 60 months. After cessation of therapy patients were followed up for 18 to 90 months. Permanent euthyroidism was seen in 70 patients (44.3%) after stopping treatment, however, 88 patients (55.7%) showed recurrence of hyperthyroidism occurring 1 to 56 months after ceasing treatment. In more than 50% recurrence of hyperthyroidism was within the first 3 months and in almost 80% within the first year after end of treatment. There was no connection either between the length of thyrostatic treatment and the recurrence rate or between the length of treatment and recurrence time. Comparison of patients with and without recurrence according to various parameters prior, during and after thyrostatic treatment indicates that there is a high risk of recurrence in patients with 1) nodular and (or) large goitres, 2) marked clinical symptomatology and delayed attainment of a euthyroid state after starting conservative treatment, and 3) the symptom of sweating remaining uninfluenced by antithyroid treatment.

Conservative treatment for patent ductus arteriosus in the preterm

NARCIS (Netherlands)

Vanhaesebrouck, Sophie; Zonnenberg, Inge; Vandervoort, Piet; Bruneel, Els; van Hoestenberghe, Marie-Rose; Theyskens, Claire

2007-01-01

BACKGROUND: A patent ductus arteriosus (PDA) is common among preterms, and prophylactic medical treatment has been advocated as the first-line approach. Conservative treatment may result in similar outcome, but without exposure to the harmful side effects of medication. A retrospective analysis

Improving predictive capabilities of environmental change with GLOBE data

Science.gov (United States)

Robin, Jessica Hill

This dissertation addresses two applications of Normalized Difference Vegetation Index (NDVI) essential for predicting environmental changes. The first study focuses on whether NDVI can improve model simulations of evapotranspiration for temperate Northern (>35°) regions. The second study focuses on whether NDVI can detect phenological changes in start of season (SOS) for high Northern (>60°) environments. The overall objectives of this research were to (1) develop a methodology for utilizing GLOBE data in NDVI research; and (2) provide a critical analysis of NDVI as a long-term monitoring tool for environmental change. GLOBE is an international partnership network of K-12 students, teachers, and scientists working together to study and understand the global environment. The first study utilized data collected by one GLOBE school in Greenville, Pennsylvania and the second utilized phenology observations made by GLOBE students in Alaska. Results from the first study showed NDVI could predict transpiration periods for environments like Greenville, Pennsylvania. In phenological terms, these environments have three distinct periods (QI, QII, and QIII). QI reflects onset of the growing season (mid March--mid May) when vegetation is greening up (NDVI 0.60). Results from the second study showed that a climate threshold of 153 +/- 22 growing degree days was a better predictor of SOS for Fairbanks than a NDVI threshold applied to temporal AVHRR and MODIS datasets. Accumulated growing degree days captured the interannual variability of SOS better than the NDVI threshold and most closely resembled actual SOS observations made by GLOBE students. Overall, biweekly composites and effects of clouds, snow, and conifers limit the ability of NDVI to monitor phenological changes in Alaska. Both studies did show that GLOBE data provides an important source of input and validation information for NDVI research.

Visualization on the Day Night Year Globe

International Nuclear Information System (INIS)

Božić, Mirjana; Vušković, Leposava; Popović, Svetozar; Popović, Jelena; Marković-Topalović, Tatjana

2016-01-01

The story about a properly oriented outdoor globe in the hands and minds of Eratosthenes, Jefferson, Milanković and science educators is presented. Having the same orientation in space as the Earth, the Day Night Year Globe (DING) shows in real time the pattern of illumination of the Earth’s surface and its diurnal and seasonal variations. It is an ideal object for the visualization of knowledge and increase in knowledge about: the form of the Earth, Earth’s rotation, Earth’s revolution around the Sun, the length of seasons, solstices, equinoxes, the longitude problem, the distribution of the Sun’s radiation over the Earth, the impact of this radiation on Earth’s climate, and how to use it efficiently. By attaching a movable vane to the poles, or adding pins around the equator to read time, DING becomes a spherical/globe-shaped sundial. So, the DING is simultaneously useful for teaching physics, geophysics, astronomy, use of solar energy and promoting an inquiry-based learning environment for students and the public. (paper)

A key component of the Globe arrives

CERN Multimedia

2003-01-01

The first component of the Palais de l'Equilibre arrived at CERN last week. Renamed the Globe of Innovation, this elegant wooden sphere will be inaugurated in October 2004. The convoy transporting the first component of the Palais de l'Equilibre, the keystone of the famous wooden globe, arrived at CERN on the night of 28th August in the middle of a violent storm and dramatic flashes of lightning. Erected in Neuchâtel last year for the EXPO.02 exhibition, the Palais de l'Equilibre was a gift to the Laboratory from the Swiss Confederation (see Bulletin 25/2003). The gift of the structure and 4 million Swiss francs, together with help from the Swiss army for the reassembly work, received the final approval of the Swiss Federal Council on 20th August 2003. Renamed the Globe of Innovation, the 27-metre-high sphere measuring 40 metres in diameter will house the Laboratory's new exhibition centre in 2005. The keystone, known as the "central vertex", is a crown measuring 6.5 m in diameter and 4.5 m high, located a...

Clinical characteristics and therapeutic effect of open globe injury

Directory of Open Access Journals (Sweden)

Mei-Lin Liu

2016-06-01

Full Text Available AIM: To analyze clinical characteristics and postoperative outcomes after open globe injury. METHODS: Demographic characteristics(age, gender, eye trauma, profession, cause of injury and injured part, as well as complications and prognosis were analyzed in 152 cases(152 eyesof open globe injury. RESULTS: Patients with open globe injury had an average age of 40.45±38.32 years old with a 5.9:1 male-to-female gender ratio. The left-to-right eye ratio was 1.27:1. Most patients were workers, farmers, or retired. The most common etiologies were scratches, boxing, and falls. Zone Ⅲ was the most commonly injured part. Iridoptosis or iris incarceration, retinal detachment, vitreal prolapse, hyphema or hypopyon, and vitreous hemorrhage were the most common complications. Visual acuity improved in 86 cases postoperatively but ophthalmectomy was still required in 25 eyes. CONCLUSION: Vision can be improved after surgery in open globe injury. However, patients are usually seriously injured and improvement is minimal, thereby resulting in a great loss to patients and society.

Luminosity declines in the Globe as it increases at the LHC

CERN Multimedia

Anaïs Schaeffer

2012-01-01

A few weeks ago, the skylight at the top of the Globe was fitted with "smart glass". The new glazing will allow the intensity of the light in the auditorium to be adjusted, thus solving the problem of sunlight reflecting on the giant screen during the day.   The Globe skylight while "off": the smart glass remains opaque. Inaugurated in 2004, the Globe of Science and Innovation has become one of the Organization's key landmarks. Housing the permanent exhibition "The Universe of Particles" (which recently received a silver design award, as reported in the last issue of the Bulletin) and a multimedia auditorium, the Globe hosts many events every year. "The Globe has rapidly become an important communication tool for CERN," enthuses Bernard Pellequer, who is in charge of event planning for the venue. "This is particularly true for the first floor, which is equipped with a giant screen. Unfortunately, we soon...

A web-system of virtual morphometric globes

Science.gov (United States)

Florinsky, Igor; Garov, Andrei; Karachevtseva, Irina

2017-04-01

Virtual globes — programs implementing interactive three-dimensional (3D) models of planets — are increasingly used in geo- and planetary sciences. We develop a web-system of virtual morphometric globes. As the initial data, we used the following global digital elevation models (DEMs): (1) a DEM of the Earth extracted from SRTM30_PLUS database; (2) a DEM of Mars extracted from the Mars Orbiter Laser Altimeter (MOLA) gridded data record archive; and (3) A DEM of the Moon extracted from the Lunar Orbiter Laser Altimeter (LOLA) gridded data record archive. From these DEMs, we derived global digital models of the following 16 local, nonlocal, and combined morphometric variables: horizontal curvature, vertical curvature, mean curvature, Gaussian curvature, minimal curvature, maximal curvature, unsphericity curvature, difference curvature, vertical excess curvature, horizontal excess curvature, ring curvature, accumulation curvature, catchment area, dispersive area, topographic index, and stream power index (definitions, formulae, and interpretations can be found elsewhere [1]). To calculate local morphometric variables, we applied a finite-difference method intended for spheroidal equal angular grids [1]. Digital models of a nonlocal and combined morphometric variables were derived by a method of Martz and de Jong adapted to spheroidal equal angular grids [1]. DEM processing was performed in the software LandLord [1]. The calculated morphometric models were integrated into the testing version of the system. The following main functions are implemented in the system: (1) selection of a celestial body; (2) selection of a morphometric variable; (3) 2D visualization of a calculated global morphometric model (a map in equirectangular projection); (4) 3D visualization of a calculated global morphometric model on the sphere surface (a globe by itself); (5) change of a globe scale (zooming); and (6) globe rotation by an arbitrary angle. The testing version of the system

Light Pollution Awareness through Globe at Night & IYL2015

Science.gov (United States)

Walker, Constance E.

2015-01-01

The International Astronomical Union (IAU) will be coordinating extensive activities to raise awareness of light pollution through running the Cosmic Light theme of the International Year of Light (IYL2015) and by partnering in particular with the popular Globe at Night program.Globe at Night (www.globeatnight.org) is an international campaign to raise public awareness of the impact of light pollution by having people measure night-sky brightness and submit observations in real-time with smart phone or later with a computer. In 2015, Globe at Night will run for 10-nights each month, an hour after sunset til before the Moon rises. Students can use the data to monitor levels of light pollution around the world, as well as understand light pollution's effects on energy consumption, plants, wildlife, human health and our ability to enjoy a starry night sky.Since its inception in 2006, more than 115,000 measurements from 115 countries have been reported. The last 9 years of data can be explored with Globe at Night's interactive world map or with the 'map app' to view a particular area. A spreadsheet of the data is downloadable from any year. One can compare Globe at Night data with a variety of other databases to see, for example, how light pollution affects the foraging habits of bats.To encourage public participation in Globe at Night during IYL2015, each month will target an area of the world that habitually contributes during that time. Special concerns for how light pollution affects that area and solutions will be featured on the Globe at Night website (www.globeatnight.org), through its Facebook page, in its newsletter or in the 365DaysofAstronomy.org podcasts.Twice during IYL there will be a global Flash Mob event, one on Super Pi Day (March 14, 2015) and a second in mid-September, where the public will be invited to take night-sky brightness measurements en masse. In April, the International Dark-Sky Week hosted by the International Dark-Sky Association will be

UNFOLDING LEONARDO DA VINCI’S GLOBE (AD 1504 TO REVEAL ITS HISTORICAL WORLD MAP

Directory of Open Access Journals (Sweden)

G. J. Verhoeven

2017-08-01

Full Text Available This paper reports in detail on the image-based modelling and unwrapping approach used to create a two-dimensional projected map of an astonishing ostrich egg globe from AD 1504. This miniature egg globe is not only the oldest extant engraved globe, but it is also the oldest post-Columbian globe of the world and the first ever to depict Newfoundland and many other territories. The intention of digitally recording the surface geometry and colour of this unique artefact was to portray the original layout of the world map used by the Florentine Renaissance artist to make this globe. In addition, it was expected to substantiate iconographical details, which are hard to study at its scale of 1:80,000,000. The ostrich egg globe is the prototype of the Lenox Globe kept at the New York Public Library. The latter is very beneficial to examine how the egg globe looked like before being glued together at its equator. On the other hand, unfolding the map engraved in the ostrich egg halves enables a more detailed study of the remarkable details visible on both globes, since the engravings on the quasi-white egg surface are much easier to discern than those of the highly reflective red copper Lenox Globe. Finally, a detailed study of the unwrapped 3D surface is essential to learn more about the world vision of its creator and the incredible efforts that went into making this globe. Thanks to some particular pictographic details as well as the way in which the engravings are applied (by a left-handed person, the globe artist can be identified as Leonardo da Vinci.

Teaching seismic methods using interactive 3D Earth globe

Science.gov (United States)

Weeraratne, D. S.; Rogers, D. B.

2011-12-01

Instructional techniques for study of seismology are greatly enhanced by three dimensional (3D) visualization. Seismic rays that pass through the Earth's interior are typically viewed in 2D slices of the Earth's interior. Here we present the use of a 3D Earth globe manufactured by Real World Globes. This globe displays a dry-erase high resolution glossy topography and bathymetry from the Smith and Sandwell data archives at its surface for interactive measurements and hands-on marking of many seismic observations such as earthquake locations, source-receiver distances, surface wave propagation, great circle paths, ocean circulation patterns, airplane trajectories, etc.. A new interactive feature (designed collaboratively with geoscientists) allows cut away and disassembly of sections of the exterior shell revealing a full cross section depicting the Earth's interior layers displayed to scale with a dry-erase work board. The interior panel spins to any azimuth and provides a depth measurement scale to allow exact measurements and marking of earthquake depths, true seismic ray path propagation, ray path bottoming depths, shadow zones, and diffraction patterns. A demo of this globe and example activities will be presented.

The Citizen-Scientist as Data Collector: GLOBE at Night, Part 2

Science.gov (United States)

Walker, C. E.; Pompea, S. M.; Ward, D.; Henderson, S.; Meymaris, K.; Gallagher, S.; Salisbury, D.

2006-12-01

An innovative program to realize light pollution education on two continents via Internet 2-based videoconferencing was begun 4 years ago by the National Optical Astronomy Observatory. Bilingual science teachers and their students in Arizona and Chile recorded the brightness of the night sky by matching its appearance toward the constellation Orion with one of 6 stellar maps of limiting magnitude. Students from both hemispheres would report their findings via videoconferences. In the last year the program has evolved in collaboration with UCAR and other partners into an international, user-friendly, web-based science event open to anyone in the world, known as GLOBE at Night. GLOBE at Night uses the same design to observe and record the visible stars toward Orion, as a means of measuring light pollution in a given location. The inaugural event occurred over 11 nights last March, when 18,000 citizen- scientists made over 4,500 observations from 96 countries. Analysis of the GLOBE at Night data set found that the brighter skies corresponded to areas with higher population density, and that most observations were taken in a location with some light pollution. The data also tended to confirm that satellite data is reliable in assessing light pollution. This session will describe our program to incorporate more technology into the GLOBE at Night program. Citizen-scientists will use sky quality meters (visible light photometers), calibrated digital photography, and GPS as a means to measure and map more accurately the brightness of the sky at selected urban and rural sites. This extension of the program is designed to aid further in teaching about the impact of artificial lighting on local environments and the ongoing loss of a dark night sky as a natural resource. We will also describe how detailed maps of selected urban areas can be used to assess lighting design, safety considerations and energy usage. Given the widespread interest in the inaugural GLOBE at Night

Implementing GLOBE in the New York City Metropolitan Area: Trials, Errors, and Successes

Science.gov (United States)

Ludman, A.; Schmidt, P.; Borman, G.

2003-12-01

The Queens College GLOBE NY Metro Partnership was created to introduce GLOBE to more than 1.5 million students in southern NY State and provide continuing support for their teachers. In our first 18 months, we have trained 185 teachers from 82 schools and will triple these numbers this year. Teachers and administrators are attracted to GLOBE by its scientific rigor, the authentic research it offers students, and its fit with NYS standards. They are also eager to interact with our science faculty. Early difficulties included problems with the "standard" 5-day GLOBE training format and misconceptions that protocols are not suitable for urban settings and that preparing for the NYS Regents exams leaves no room for GLOBE. We held information meetings for school districts and for Queens high schools before our first workshop. These identified the most committed schools, energetic teachers, and potential implementation problems. Creative participants at these meetings countered the misconceptions and suggested solutions to the problems better than any outsider could, and generated an atmosphere leading to nearly 100% recruitment. The following stratagems have worked well: a close working relationship with the NYC Dept of Education, BOCES, and other environmental educators; affiliations with government agencies and community environmental groups; two bribes (giving a GLOBE instrument kit and GPS unit to each school that we train and awarding graduate or professional development credits for GLOBE training); a user-friendly training format (an initial 3-day workshop followed by two optional days for hydrology and land use); lending seldom-used items (e.g. soil auger) when needed; building a sense of GLOBE community with a graduation "ceremony", local website (www.qc.edu/qcglobe) and newsletter, phone and email helplines, and annual pedagogy and student research conferences. We also urge that three teachers be trained from each school in order to build local GLOBE support

In vitro micropropagation and mycorrhizal treatment influences the polyphenols content profile of globe artichoke under field conditions.

Science.gov (United States)

Pandino, Gaetano; Lombardo, Sara; Antonino, Lo Monaco; Ruta, Claudia; Mauromicale, Giovanni

2017-09-01

The commercial importance of plant tissue culture has grown in recent years, reflecting its application to vegetative propagation, disease elimination, plant improvement and the production of polyphenols. The level of polyphenols present in plant tissue is influenced by crop genotype, the growing environment, the crop management regime and the post-harvest processing practice. Globe artichoke is a significant component of the Mediterranean Basin agricultural economy, and is rich in polyphenols (phenolic acids and flavones). Most commercially grown plants are derived via vegetative propagation, with its attendant risk of pathogen build-up. Here, a comparison was drawn between the polyphenol profiles of conventionally propagated and micropropagated/mycorrhized globe artichoke plants. Micropropagation/mycorrhization appeared to deliver a higher content of caffeoylquinic acids. The accumulation of these compounds, along with luteolin and its derivatives, was not season-dependent. Luteolin aglycone was accumulated preferentially in the conventionally propagated plants. Overall, it appeared that micropropagation/mycorrhization enhanced the accumulation of polyphenols. Copyright © 2017. Published by Elsevier Ltd.

Eratosthenes' teachings with a globe in a school yard

International Nuclear Information System (INIS)

Božić, Mirjana; Ducloy, Martial

2008-01-01

A globe, in a school or university yard, which simulates the Earth's orientation in space, could be a very useful and helpful device for teaching physics, geometry, astronomy and the history of science. It would be very useful for science education to utilize the forthcoming International Year of the Planet Earth 2008 and the International Year of Astronomy 2009 by installing globes in many school and university courtyards

Globes, Maps, Photographs: Geographic Tools.

Science.gov (United States)

McDermott, Paul D.; And Others

This compilation of reprinted articles that originally appeared in the Journal of Geography from September 1969 through the May 1970 issues, is intended to help teachers use globes, maps, and photographs with skill and understanding. The articles were designed with several objectives in mind: 1) to provide information regarding the design,…

Water and the conservation movement

Science.gov (United States)

Leopold, Luna Bergere

1958-01-01

Every age has its unique touchstone, its hallmark. The Nineties were thought gay. The Twenties had jazz and John Held, Jr. The Thirties had breadlines, dust bowls, the forgotten man. And each recent period has been studded with so many flashy gems, both paste and genuine, that no hallmark would alone be enough to label it.Of the present age, one of the nameplates will carry the word "Conservation." The first time a museum visitor walks by that label he will probably stop, push back the plexiglas globe of his space helmet and say to himself, "I never thought that conservation was a keynote of the Fifties." But I imagine he might agree as the pathetic truth of that label dawned on his tired body, accustomed to canned entertainment, synthetic flavors, and fighting the afternoon traffic of the jet lanes. I can imagine him musing: "Conservation, the hallmark of the Fifties. Somebody about that time said about something or other, 'too little and too late.'"

Dark Skies Awareness through the GLOBE at Night Citizen-Science Campaign

Science.gov (United States)

Walker, C. E.

2011-10-01

The emphasis in the international citizen-science, star-hunting campaign, GLOBE at Night, is in bringing awareness to the public on issues of light pollution. Light pollution threatens not only observatory sites and our "right to starlight", but can affect energy consumption, wildlife and health. GLOBE at Night has successfully reached a few hundred thousand citizen-scientists during the annual 2-week campaign over the past 6 years. Provided is an overview, update and discussion of what steps can be taken to improve programs like GLOBE at Night.

EYE TRAUMA. OPEN GLOBE INJURY MANAGEMENT

Directory of Open Access Journals (Sweden)

Mojca Globočnik Petrovič

2004-05-01

Full Text Available Background. Ocular trauma is important cause of blindness. Birmingham Eye Trauma Terminology allows us to use a standardized eye injury terminology which permits an unambigous interpretation. The Eye Injury Registry enables the analysis of medical, epidemyologic and social data.The most frequent ocular injury ocular contusion has a relatively good prognosis. An adequate primary ocular repair and correct timing of pars plana vitrectomy are very important in open globe injury management. There still exist some controversial issues concerning the role of posterior segment surgery in open globe injuries. These include timing of surgery, prophylactic scleral buckle placement and a proper use of systemic and intravitreal antibiotics.Conclusions. With adequate primary ocular repair, the use of systemic, intravitreal antibiotics, scleral buckling and proper timing for pars plana vitrectomy the prognosis for ocular trauma cases can be better.

Genetic mapping and annotation of genomic microsatellites isolated from globe artichoke

NARCIS (Netherlands)

Acquadro, A.; Lanteri, S.; Scaglione, D.; Arens, P.F.P.; Vosman, B.; Portis, E.

2009-01-01

Cynara cardunculus includes three taxa, the globe artichoke (subsp. scolymus L. Hegi), the cultivated cardoon (var. altilis) and their progenitor, the wild cardoon (var. sylvestris). Globe artichoke is an important component of the Mediterranean rural economy, but its improvement through breeding

The Globe reopens its doors

CERN Multimedia

CERN Bulletin

2016-01-01

After a year of work, the newly renovated Globe of Science and Innovation will open its doors again at 10 a.m. on Tuesday, 19 April. The “Universe of Particles” exhibition has been updated and will be open to the public, free of charge, from 10 a.m. to 5 p.m., Monday to Saturday (except during official CERN closures). The Globe’s programme of lectures and events for the general public will restart at the end of April. What’s on at the Globe in April and May: - 28 April at 6.30 p.m.: Theatre – “Curie_Meitner_Lamarr_indivisible”, a play that pays tribute to the lives of three exceptional women in the field of science and technology (in English). Reservations: http://indico.cern.ch/e/cmli - 10 May at 8.30 p.m.: Lecture – “Le modèle du CERN et les grands défis mondiaux” (“The CERN model and the key global challenges”) by Michel Spiro (in French with simultaneous ...

Determining Light Pollution of the Global Sky: GLOBE at Night

Science.gov (United States)

Henderson, S.; Meymaris, K.; Ward, D.; Walker, C.; Russell, R.; Pompea, S.; Salisbury, D.

2006-05-01

GLOBE at Night is an international science event designed to observe and record the visible stars as a means of measuring light pollution in a given location. Increased and robust understanding of our environment requires learning opportunities that take place outside of the conventional K-12 classroom and beyond the confines of the school day. This hands-on learning activity extended the traditional classroom and school day last March with a week of nighttime sky observations involving teachers, students and their families. The quality of the night sky for stellar observations is impacted by several factors including human activities. By observing cloud cover and locating specific constellations in the sky, students from around the world learned how the lights in their community contribute to light pollution, exploring the relationship between science, technology and their society. Students learned that light pollution impacts more than just the visibility of stars at night. Lights at night impact both the biology and ecology of many species in our environment. Students were able to participate in this global scientific campaign by submitting their observations through an online database, allowing for authentic worldwide research and analysis by participating scientists. Students and their families learned how latitude and longitude coordinates provide a location system to map and analyze the observation data submitted from around the globe. The collected data is available online for use by students, teachers and scientists worldwide to assess how the quality of the night sky varies around the world. This session will share how students and scientists across the globe can explore and analyze the results of this exciting campaign. GLOBE at Night is a collaborative effort sponsored by The GLOBE Program, the National Optical Astronomy Observatory (NOAO), Centro de Apoyo a la Didactica de la Astronomia (CADIAS), Windows to the Universe, and ESRI. The GLOBE Program is

The Citizen-Scientist as Data Collector: GLOBE at Night, Part 1

Science.gov (United States)

Ward, D. L.; Henderson, S.; Meymaris, K.; Walker, C.; Pompea, S. M.; Gallagher, S.; Salisbury, D.

2006-12-01

GLOBE at Night is an international science event designed to observe and record the visible stars as a means of measuring light pollution in a given location. Increased and robust understanding of our environment requires learning opportunities that take place outside of the conventional K-12 classroom and beyond the confines of the school day. This hands-on learning activity extended the traditional classroom and school day through 11 nights last March, when 18,000 citizen-scientists made over 4,500 observations from 96 countries. Utilizing the international networking capabilities of The GLOBE Program, GLOBE at Night was designed to make data collection and input user-friendly. Citizen-scientists were able to participate in this global scientific campaign by submitting their observations through an online database, allowing for authentic worldwide research and analysis by participating scientists. The data collected is available online in a variety of formats for use by students, teachers and scientists worldwide to assess how the quality of the night sky varies around the world. Using the online analysis tools provided by ESRI, participants were able to compare the observed data with population density and nighttime lighting datasets (DMSP Earth at Night). This comparison allowed correlations between observed data patterns and commonly used indices of population density and energy usage. This session will share our results and demonstrate how students and scientists across the globe can explore and analyze the results of this exciting campaign. We will discuss how the project team planned and executed the project in such a way that non-astronomers were able to make valid and useful contributions. We will also discuss lessons learned and best practices based on the 2006 campaign. GLOBE at Night is a collaborative effort sponsored by The GLOBE Program, the National Optical Astronomy Observatory (NOAO), Centro de Apoyo a la Didactica de la Astronomia (CADIAS

Conservative Treatment for Bony Healing in Pediatric Lumbar Spondylolysis.

Science.gov (United States)

Sakai, Toshinori; Tezuka, Fumitake; Yamashita, Kazuta; Takata, Yoichiro; Higashino, Kosaku; Nagamachi, Akihiro; Sairyo, Koichi

2017-06-15

A retrospective review of prospectively collected data. The aim of this study was to investigate recent outcomes of conservative treatment for bony healing in pediatric patients with lumbar spondylolysis (LS) and to identify the problems that need to be resolved. Several diagnostic and therapeutic techniques for LS have been developed recently, leading to better outcomes for bony healing. Overall, 63 consecutive pediatric patients (53 boys and 10 girls) with LS (average age: 13.8 years; range: 6-17 years) were analyzed. Diagnosis and staging (very early, early, progressive, and terminal) were based on multidetector computed tomography (CT) scans and magnetic resonance imaging (MRI). For all patients except those with terminal-stage pars defect, conservative treatment included rest, avoidance of sports, and the use of a thoraco-lumbo-sacral-type trunk brace. Follow-up MRI was performed monthly. When the signal changes resolved, CT scans were obtained to assess bony healing. Three patients dropped out during the study period. A total of 60 patients were included (50 boys and 10 girls) in this study (follow-up rate: 95.2%), with 86 instances of LS (very early: 36, early: 16, progressive: 15, terminal: 19) in 65 laminae. In the very early stage, the bony healing rate was 100%, and average treatment period was 2.5 months (range: 1-7 months). In the early stage, the bony healing rate was 93.8%, and the average treatment period was 2.6 months (range: 1-6 months). In the progressive stage, the bony healing rate was 80.0%, and the average treatment period was 3.6 months (range: 3-5 months). The average overall recurrence rate was 26.1%. All patients showing recurrence eventually achieved bony healing. High bony healing rates and short treatment periods were observed with conservative treatment in pediatric patients with LS. However, the recurrence rates were relatively high. This issue should be targeted in future studies. 2.

Epidemiologic characteristics and outcomes of open globe injury in Shanghai

Directory of Open Access Journals (Sweden)

Yong-Rong Ji

2017-08-01

Full Text Available AIM: To investigate the epidemiologic characteristics and outcomes of open globe injury in Shanghai. METHODS: A retrospective study was conducted for 148 unilateral open globe injury cases presenting to a tertiary referral hospital of Shanghai. Electronic medical records were reviewed and phone surveys were conducted to collect and analyze 1 background of patient; 2 setting of injury and clinical signs at presentation; 3 treatment procedure and outcome; 4 quality of life after injury. RESULTS: There were more male patients (77.03% than females (22.97%, more temporary habitants (79.05% than residents (20.95%. The subjects in this study presented a significantly lower constitutional status of education than that of the whole Shanghai population (P<0.001. Occupational injury was the first cause of injuries (39.86%, followed by home accident (20.27%, road accident (16.89%, violent behavior (16.89% and outdoor injury (6.08%. The 143 subjects (96.62% were not wearing spectacles at the time of injury. Of all patients, 77 subjects (52.03% had the outcome of no vision (including enucleation. The classification and regression tree (CART prognosis presents 59.58% sensitivity to predict visual survival correctly and 80.19% specificity to predict no vision correctly. The patients whose injured eye had no vision reported more reduction of life quality. CONCLUSION: We found that male subject, temporary habitants, low educational status and no eyewear are risk factors of open globe injury in Shanghai. Occupational injury is the leading cause. CART analysis presents a certain agreement to the actual visual outcome. The injury imposes negative impact on quality of life especially in no vision cases. The education of eye protection may help to avoid the injury.

Overactive bladder syndrome in the older woman: conservative treatment.

Science.gov (United States)

Stewart, Ellie

2009-11-01

Over active bladder syndrome (OAB) is the most common cause of urinary incontinence in the older population (Gadgil and Wagg, 2008). Many women do not seek medical help and advice as they consider it to be an inevitable part of ageing. It can have significant impact on sufferers' lives and can contribute to an increased risk of falls, reduced quality of life, social isolation and depression. It is also known to be hugely underreported as patients are often too embarrassed to discuss their symptoms with members of their family or health professionals. OAB syndrome can however, be treated effectively in primary care with conservative, nurse-led treatments. This article will discuss the causes, implications, assessment and conservative treatments available to women over 65 years old presenting with OAB syndrome in primary care.

Factors determining esthetic outcome after breast cancer conservative treatment

DEFF Research Database (Denmark)

Cardoso, Maria J; Cardoso, Jaime; Santos, Ana C

2007-01-01

with lower body mass index (BMI) and premenopausal status obtained better cosmetic results. In the group of tumor- and treatment-related factors, larger removed specimens, clearly visible scars, the use of chemotherapy and longer follow-up period were associated with less satisfactory results......The aim of this study was to evaluate the factors that determine esthetic outcome after breast cancer conservative treatment, based on a consensual classification obtained with an international consensus panel. Photographs were taken from 120 women submitted to conservative unilateral breast cancer...... surgery (with or without axillary surgery) and radiotherapy. The images were sent to a panel of observers from 13 different countries and consensus on the classification of esthetic result (recorded as excellent, good, fair or poor) was obtained in 113 cases by means of a Delphi method. For each patient...

Breast-conserving treatment of early breast cancer

International Nuclear Information System (INIS)

Pirtoli, L.; Bellezza, A.; Pepi, F.; Tucci, E.; Crociani, M.; Crastolla, A.M.; Farzad, M.; Bindi, M.

1993-01-01

Results of large prospective trials, often based on selected series and optimal treatment techniques, indicate that breast conserving therapy is appropriate for most patients with early breast cancer. Questions remain regarding the therapeutic outcome in common practice. We report on a series of 206 consecutive, unselected patients treated with current radiotherapy procedures. The Kaplan-Meier evaluation showed 5- and 8-year survival rates (93%, 91%), distant disease-free survival rates (87%, 85%) and local relapse-free survival rates (90%, 88%) that were comparable to those of the conservative arms in reported randomised trials and to the data from retrospective studies reported by authoritative institutions. However, subanalysis according to prognostic factors such as menopausal status, age and axillary nodal status was of limited value, due to the small number of cases. (orig.)

A Review of Global Learning & Observations to Benefit the Environment (GLOBE)

Science.gov (United States)

2010-04-01

review (Yoder et al., 2008) of the GPO performance, NASA continued the cooperative agreement with UCAR. Another external review ( Bybee et al., 2008) of...Submitted by the Program Office External Review Committee. Bybee , Rodger W. (Chair), 2008. NASA External Review of a GLOBE Proposal, The Globe

Evaluation of the conservative treatment of Trigger finger by local instillation of corticosteroids

Directory of Open Access Journals (Sweden)

Muris Pecar

2011-12-01

Full Text Available Introduction: Trigger Finger (tenosynovitis stenosans is a specific, named disease from a group of repetitive strain injury (RSI diseases, caused by inflammation which results in difficulties during muscle contraction and weakened and painful tendon movement. It is common in the outpatient physical medicine and rehabilitation practice. The aim of our study was to evaluate the success of conservative treatment of Trigger Finger by local instillation of corticosteroids.Methods: The study was designed as an observational and open analysis of the results of conservative treatment of 45 patients. We used precise instillation of steroid anti-inflammatory antirheumatic drugs in the area of patho-anatomic, microtraumatic injuries of tendon and its sheath. Patients were evaluated before and after the treatment with 0 to 5 evaluation score scale. The data were analyzed using X2 test.Results: Most of the patients had evaluation score of 2, 3 and 4, before the treatment. After the treatment 10 (29% patients had achieved score 4 and 35 (71% patients had achieved score 5. All of the patients with score 5 had excellent working ability with full working capacity. Other patients had well-preserved working ability, which improved to excellent in maximum of 7 days.Conclusions: Conservative treatment of Trigger finger shows good therapeutic effects and taking into account the benefits, convenience and generally lower cost of conservative treatment for the patient, should be considered as an effective alternative to surgical treatment.

Traumatic Globe Subluxation and Intracranial Injury Caused by Bicycle Brake Handle.

Science.gov (United States)

Poroy, Ceren; Cibik, Cansu; Yazici, Bulent

2016-09-01

Penetration of a bicycle brake handle into the orbit is a rare and serious type of trauma. Globe subluxation due to such trauma has not been previously reported. A 10-year-old girl presented after falling from a bicycle, which resulted in the handbrake penetrating her right upper eyelid. On examination, the globe was subluxated anteriorly, there was no light perception, and the pupilla was fixed and dilated. Radiologic studies revealed orbitonasal fractures, hemorrhage, emphysema in the orbit and cranium, and rupture of the extraocular muscles. The globe was replaced into the orbit with the help of lateral cantholysis and orbital septotomy. During 22 months of follow-up, the globe remained intact, but total loss of vision, blepharoptosis, and extraocular motility restriction persisted. This case and previous reports show that bicycle brake handles can cause severe, penetrating orbital and cerebral traumas that can result in vision loss or fatality. Brake handles should be designed to protect bicyclists from such injuries.

The GLOBE Program in Alabama: A Mentoring Approach to State-wide Implementation

Science.gov (United States)

Cox, G. N.

2003-12-01

Established in 1997, the GLOBE in Alabama (GIA) partnership has trained more than 1,000 teachers in almost 500 schools - over 25% of the total number of K-12 schools in Alabama. Over those five years, GIA has strived to achieve recognition of GLOBE as the "glue" to Alabama's new education program, the Alabama Math, Science and Technology Initiative (AMSTI). In 2003, GIA trained over 370 AMSTI K-8 teachers at two AMSTI hub sites in north Alabama. As the AMSTI program grows with the addition of future hub sites (eleven are planned), GIA must ready itself to train thousands of AMSTI teachers during the two-week summer professional development institutes that are part of AMSTI. A key component of AMSTI is a mentoring program conducted by math and science specialists - classroom educators loaned to the AMSTI hub sites by the school systems each hub site serves. The AMSTI mentoring program mirrors the GIA mentoring model begun in 1999 that originally funded regional GLOBE master teachers to provide technical assistance, feedback, and coaching for other GLOBE teachers. In schools where GIA mentor teachers were working, nearly a 100% increase in GLOBE student data reporting was noted. The GIA mentors now work within the hub site framework to ensure implementation of GLOBE as an integrated part of AMSTI. With the continued support of the State of Alabama, GIA will establish a network of mentors who work with the AMSTI hub site specialists in providing support for all AMSTI teachers. GIA is administered by the National Space Science and Technology Center, a partnership between NASA and the State of Alabama's seven research universities. Operational funding for GIA has been provided by the University of Alabama in Huntsville's Earth System Science Center, the NASA Marshall Space Flight Center, the Alabama Space Grant Consortium, The Alabama Department of Economic and Community Affairs, the Alabama State Department of Education, and Legacy. GIA has been able to build on these

Scoliosis: review of types of curves, etiological theories and conservative treatment.

Science.gov (United States)

Shakil, Halima; Iqbal, Zaheen A; Al-Ghadir, Ahmad H

2014-01-01

Scoliosis is the deviation in the normal vertical spine. Although there are numerous studies available about treatment approaches for scoliosis, the numbers of studies that talk about its etiology and pathology are limited. Aim of this study was to discuss the different types of scoliosis; its curves and etiological theories; and to note their implication on its treatment. We examined various electronic databases including Pub MED, Medline, Cinhal, Cochrane library and Google scholar using key words "scoliosis", "etiology", "pathology" and "conservative treatment". References of obtained articles were also examined for cross references. The search was limited to articles in English language. A total of 145 papers, about Prevalence, History, Symptoms, classification, Biomechanics, Pathogenesis, Kinematics and Treatment of scoliosis were identified to be relevant. To choose the appropriate treatment approach for scoliosis we need to understand its etiology and pathogenesis first. Early intervention with conservative treatment like physiotherapy and bracing can prevent surgery.

Clinical Significance of Monitoring Serum β-HCG in the Conservative Treatment of Ectopic Pregnancy

International Nuclear Information System (INIS)

Chen Xue

2010-01-01

To explore the clinical value of the serum β-HCG (human chorionic gonadotrophin) in the conservative treatment of ectopic pregnancy, the serum β-HCG levels in 118 patients with ectopic pregnancy were measured with RIA. The results showed that the serum β-HCG levels in patients with successful conservative treatment of ectopic pregnancy were all less than 200mIU/mL. The patients require a surgical treatment to reach <200mIU/mL serum β-HCG concentration were only 26.3%. There was significant difference between two groups (P<0.01). The monitoring of serum β-HCG was very useful in the diagnosis, the choice of treatment measures and the evaluation of conservative treatment effect of ectopic pregnancy. In the course of treatment of ectopic pregnancy, serum β-HCG is a good marker in determining the success or failure of treatment. (authors)

Traumatic eye ball luxation: A stepwise approach to globe salvage

Directory of Open Access Journals (Sweden)

Himika Gupta

2017-10-01

Full Text Available Craniofacial trauma is often associated with orbital and ocular injuries. We report a case of a 21-year-old male with motor vehicular accident, orbital roof blow-in fracture, cerebrospinal fluid (CSF leak, and left sided globe luxation with corneal abrasion and complete conjunctival denuding. The patient was managed by a multispeciality team and the eyeball was protected by amniotic membrane graft (AMG biological dressing with novel use of inverted sterile metallic bowl as mechanical protection till the patient stabilized. During surgery, eyeball was reposited and ocular surface was reconstructed using amniotic membrane and symblepharon ring. Surgical correction and plating of the facial fractures and dural repair with autologus tensor fascia lata was done. Post surgery ocular surface was intact, ocular motility was well preserved and the globe was prephthisical. Traumatic eyeball luxation is a rare, but dramatic presentation which may occur in a blow in fracture when the intra orbital volume reduces and expels the eye ball out of the socket. This may be associated with extra ocular muscle rupture or optic nerve avulsion. The visual prognosis is nil in majority cases. However, the management is targeted towards globe preservation in view of psychological benefit and ease of cosmetic or prosthetic rehabilitation. Knowing the mechanism of luxation helps to plan the management. A stepwise approach for globe salvage is recommended. Team efforts to take care of various morbidities with special steps to safeguard the eye help to optimize outcomes. Keywords: Traumatic eyeball luxation, Blow in orbital fractures, Amniotic membrane graft for ocular surface, Globe reposition

Conservative treatment of acute knee osteoarthritis: A review of the Cochrane Library

Directory of Open Access Journals (Sweden)

Emerito Carlos Rodriguez-Merchan

2016-05-01

Conclusions: Five main strategies for the conservative treatment of knee osteoarthritis exist that must be used before indicating surgical treatment: medical treatment, physical medicine and rehabilitation, intra-articular injections, acupuncture, and self-management education programs.

GLOBE and the Earth SySTEM Model in Teacher Preparation

Science.gov (United States)

Jabot, M.; Moore, J.; Dorofy, P.

2017-12-01

This presentation will share the growing body of work linking ArcMap and GLOBE and the Earth SySTEM approach in the development of preservice teachers. Our work is linking the power of ArcMap with the vast database of GLOBE in a unique way that links the power of geospatial technologies in shaping the planning for and delivery of science instruction in the P-5 classroom.

Turning Content into Conversation: How The GLOBE Program is Growing its Brand Online

Science.gov (United States)

Zwerin, R.; Randolph, J. G.; Andersen, T.; Mackaro, J.; Malmberg, J.; Tessendorf, S. A.; Wegner, K.

2012-12-01

Social Media is now a ubiquitous way for individuals, corporations, governments and communities to communicate. However, the same does not hold quite as true for the science community as many science educators, thought leaders and science programs are either reluctant or unable to build and cultivate a meaningful social media strategy. This presentation will show how The GLOBE Program uses social media to disseminate messages, build a meaningful and engaged following and grow a brand on an international scale using a proprietary Inside-Out strategy that leverages social media platforms such as Facebook, LinkedIn, Twitter, YouTube and Blogs to significantly increase influencers on a worldwide scale. In addition, this poster presentation will be interactive, so viewers will be able to touch and feel the social experience. Moreover, GLOBE representatives will be on hand to talk viewers through how they can implement a social media strategy that will allow them to turn their content into meaningful conversation. About The GLOBE Program: GLOBE is a science and education program that connects a network of students, teachers and scientists from around the world to better understand, sustain and improve Earth's environment at local, regional and global scales. By engaging students in hands-on learning of Earth system science, GLOBE is an innovative way for teachers to get students of all ages excited about scientific discovery locally and globally. To date, more than 23 million measurements have been contributed to the GLOBE database, creating meaningful, standardized, global research-quality data sets that can be used in support of student and professional scientific research. Since beginning operations in 1995, over 58,000 trained teachers and 1.5 million students in 112 countries have participated in GLOBE. For more information or to become involved, visit www.globe.gov.

Whole-globe biomechanics using high-field MRI.

Science.gov (United States)

Voorhees, Andrew P; Ho, Leon C; Jan, Ning-Jiun; Tran, Huong; van der Merwe, Yolandi; Chan, Kevin; Sigal, Ian A

2017-07-01

The eye is a complex structure composed of several interconnected tissues acting together, across the whole globe, to resist deformation due to intraocular pressure (IOP). However, most work in the ocular biomechanics field only examines the response to IOP over smaller regions of the eye. We used high-field MRI to measure IOP induced ocular displacements and deformations over the whole globe. Seven sheep eyes were obtained from a local abattoir and imaged within 48 h using MRI at multiple levels of IOP. IOP was controlled with a gravity perfusion system and a cannula inserted into the anterior chamber. T2-weighted imaging was performed to the eyes serially at 0 mmHg, 10 mmHg, 20 mmHg and 40 mmHg of IOP using a 9.4 T MRI scanner. Manual morphometry was conducted using 3D visualization software to quantify IOP-induced effects at the globe scale (e.g. axial length and equatorial diameters) or optic nerve head scale (e.g. canal diameter, peripapillary sclera bowing). Measurement sensitivity analysis was conducted to determine measurement precision. High-field MRI revealed an outward bowing of the posterior sclera and anterior bulging of the cornea due to IOP elevation. Increments in IOP from 10 to 40 mmHg caused measurable increases in axial length in 6 of 7 eyes of 7.9 ± 5.7% (mean ± SD). Changes in equatorial diameter were minimal, 0.4 ± 1.2% between 10 and 40 mmHg, and in all cases less than the measurement sensitivity. The effects were nonlinear, with larger deformations at normal IOPs (10-20 mmHg) than at elevated IOPs (20-40 mmHg). IOP also caused measurable increases in the nasal-temporal scleral canal diameter of 13.4 ± 9.7% between 0 and 20 mmHg, but not in the superior-inferior diameter. This study demonstrates that high-field MRI can be used to visualize and measure simultaneously the effects of IOP over the whole globe, including the effects on axial length and equatorial diameter, posterior sclera displacement and bowing, and even

Engaging the Public in the Citizen Science GLOBE at Night Campaign

Science.gov (United States)

Walker, Constance E.; Sparks, R. T.; Pompea, S. M.

2011-05-01

The emphasis in the international star-hunting campaign, GLOBE at Night, is in bringing awareness to the public on issues of light pollution. Light pollution threatens not only observatory sites and our "right to starlight", but can affect energy consumption, wildlife and health. GLOBE at Night has successfully reached a few 100,000 citizen-scientists. What steps can be taken to improve it? To promote the campaign via popular social media, GLOBE at Night created Facebook and Twitter pages. To increase participation in the 2011 campaign, children and adults submitted their sky brightness measurements in real time with smart phones or tablets using the web application at www.globeatnight.org/webapp/. With smart phones and tablets, the location, date and time register automatically. For those without smart mobile devices, user-friendly tools on the GLOBE at Night report page were reconfigured to determine latitude and longitude more easily and accurately. To increase the robustness of the data, 2 new approaches were taken. GLOBE at Night prototyped an "Adopt a Street” program in Tucson. The aim was for people to adopt different major or semi-major streets and take measurements every mile or so for the length of the street. The grid of measurements would canvas the town, allowing for comparisons of light levels over time (hours, days, years) or search for dark sky oases or light polluted areas. The increase to 2 campaigns in 2011 re-enforces these studies. The intent is to offer the program year-round for seasonal studies. The data can also be used to compare with datasets on wildlife, health, and energy consumption. Recently, NOAO and the Arizona Game and Fish Department have started a project with GLOBE at Night data and bat telemetry to examine a dark skies corridor in Tucson where the endangered bats fly. In our presentation, results of our efforts are discussed.

Comparing surgical repair with conservative treatment for degenerative rotator cuff tears : a randomized controlled trial

NARCIS (Netherlands)

Lambers Heerspink, Okke; van Raay, Jos J. A. M.; Koorevaar, Rinco C. T.; van Eerden, Pepijn J. M.; Westerbeek, Robin E.; van 't Riet, Esther; van den Akker-Scheek, Inge; Diercks, Ronald L.

Background: Good clinical results have been reported for both surgical and conservative treatment of rotator cuff tears. The primary aim of this randomized controlled trial was to compare functional and radiologic improvement after surgical and conservative treatment of degenerative rotator cuff

Rock the Globe

CERN Multimedia

Laëtitia Pedroso

2010-01-01

Created in 2005, the Swiss rock band "Wind of Change" is now candidate for the Eurovision Song Contest 2011 with a new song " Night & Light " with the music video filmed at CERN.   With over 20 gigs under their belt and two albums already released, the five members of the band (Alex Büchi, vocals; Arthur Spierer, drums; David Gantner, bass; Romain Mage and Yannick Gaudy, guitar) continue to excite audiences. For their latest composition "Night & Light", the group filmed their music video in the Globe of Science and Innovation. Winning the Eurovision contest would be a springboard in their artistic career for these young musicians. The selection results will be available December 11, 2010.      

A comparison of conservative and invasive dental approaches in the treatment of tension-type headache.

Science.gov (United States)

Troeltzsch, Markus; Messlinger, Karl; Brodine, Brian; Gassling, Volker; Troeltzsch, Matthias

2014-10-01

To investigate the efficacy of conservative dental treatment (occlusal splint and pharmacologic therapy) and invasive therapy (prosthetic restorations) in the treatment of tension-type headache (TTH). The study sample was composed of 70 patients who presented with symptomatic TTH and were assigned to three treatment groups according to their treatment needs. Group A (30 patients): a conservative treatment protocol with a combination of an occlusal splint and analgesic and muscle relaxant medication. Group B (10 patients): invasive prosthodontic procedures. Group C (30 patients): patients who refused any type of treatment but consented to the study served as a control group. Pain quality was measured with the Headache Impact Test (HIT-6). The statistical analysis was performed with the Wilcoxon rank test (P≤.05). Conservative treatment with splints and analgesic medication and invasive treatment by prosthetic rehabilitation relieved the TTH symptoms. The patients who received treatment experienced a significant reduction in their discomfort after 6 months (P≤.01), whereas the patients who refused therapy remained, on average, at the same pain level (P≤.117). In group A, the HIT-6 score was reduced for 26 patients, and in group B for 8 patients. In group C a reduction of HIT-6 scores was observed in 10 patients. Conservative or invasive occlusal adjustments may serve as a useful tool in the treatment of TTH.

GLOBE Observer: A new tool to bring science activities and measurements home

Science.gov (United States)

Riebeek Kohl, H.; Murphy, T.

2016-12-01

The Global Learning and Observations to Benefit the Environment (GLOBE) Program is an international science and education program that provides students and the public worldwide with the opportunity to participate in data collection and the scientific process, and contribute meaningfully to our understanding of the Earth system and global environment. For more than 20 years, GLOBE-trained teachers have been leading environmental data collection and student research in the classroom. In 2016, GLOBE expanded to invite data collection from citizen scientists of all ages through a simple smart phone app. The app makes it possible for students to take GLOBE data (environmental observations) outside of school with their families. It enables a museum, park, youth organization, or other informal institution to provide a simple take-home activity that will keep patrons engaged in environmental science from home. This presentation will provide a demonstration of the app and will provide examples of its use in informal settings.

Pediatric open globe injury: A review of the literature

Directory of Open Access Journals (Sweden)

Xintong Li

2015-01-01

Full Text Available Open globe injury (OGI is a severe form of eye trauma estimated at 2-3.8/100,000 in the United States. Most pediatric cases occur at home and are the result of sharp object penetration. The aim of this article is to review the epidemiology, diagnosis, management, and prognosis of this condition by conducting a systematic literature search with inclusion of all case series on pediatric OGI published between 1996 and 2015. Diagnosis of OGI is based on patient history and clinical examination supplemented with imaging, especially computed tomography when indicated. Few prospective studies exist for the management of OGI in pediatric patients, but adult recommendations are often followed with success. The main goals of surgical management are to repair the open globe and remove intraocular foreign bodies. Systemic antibiotics are recommended as medical prophylaxis against globe infection, or endophthalmitis. Other complications are similar to those seen in adults, with the added focus of amblyopia therapy in children. Severe vision decline is most likely due to traumatic cataracts. The ocular trauma score, a system devised to predict final visual acuity (VA in adults, has proven to be of prognostic value in pediatric OGI as well. Factors indicating poor visual prognosis are young age, poor initial VA, posterior eye involvement, long wound length, globe rupture, lens involvement, vitreous hemorrhage, retinal detachment, and endophthalmitis. A thorough understanding of OGI and the key differences in epidemiology, diagnosis, management, and prognosis between adults and children is critical to timely prevention of posttraumatic vision loss early in life.

Globe hosts launch of new processor

CERN Multimedia

2006-01-01

Launch of the quadecore processor chip at the Globe. On 14 November, in a series of major media events around the world, the chip-maker Intel launched its new 'quadcore' processor. For the regions of Europe, the Middle East and Africa, the day-long launch event took place in CERN's Globe of Science and Innovation, with over 30 journalists in attendance, coming from as far away as Johannesburg and Dubai. CERN was a significant choice for the event: the first tests of this new generation of processor in Europe had been made at CERN over the preceding months, as part of CERN openlab, a research partnership with leading IT companies such as Intel, HP and Oracle. The event also provided the opportunity for the journalists to visit ATLAS and the CERN Computer Centre. The strategy of putting multiple processor cores on the same chip, which has been pursued by Intel and other chip-makers in the last few years, represents an important departure from the more traditional improvements in the sheer speed of such chips. ...

The value of radiotherapy in breast-conserving treatment

International Nuclear Information System (INIS)

Kurtz, J.M.

1994-01-01

Breast conserving treatment owes its legitimacy to the ability of radiotherapy (RT), in conjunction with limited surgery, to provide local control equivalent to that associated with total mastectomy. This paper will be concerned exclusively with the treatment of the breast, since indications for RT of lymph node areas are independent of the type of breast surgery employed. Randomized trials have enabled quantitation of the effect of reduction in recurrence risk compared to surgery alone. Even though local recurrence is a predictor of metastatic disease, its prevention by breast RT has not yet been shown to improve survival. Thus the main benefits of breast RT relate to preventing the consequences of local failure, namely breast loss. With modern RT techniques, cosmetic results should be satisfactory in 90% of preserved breast. The main clinical research areas concern the optimal sequencing of surgery, RT and chemotherapy, the improvement of local control in high-risk patients, the extension of breast conservation to more advanced cases by the use of neo-adjuvant chemotherapy and RT, the identification of early-stage patients who could be treated with wide excision alone, and the value of RT in ductal in situ carcinomas. (author)

GlobeLand30 shows little cropland area loss but greater fragmentation in China

Science.gov (United States)

Yu, Qiangyi; Hu, Qiong; van Vliet, Jasper; Verburg, Peter H.; Wu, Wenbin

2018-04-01

Understanding of cropland dynamics in a large geographical extent is mostly based on observations of area change, while the changes in landscape pattern are hardly assessed. The total amount of cropland in China has remained relatively stable in recent years, which might suggest there was little change. In this analysis, we combine the number of cropland patches (NP) with the total cropland area (TA) for a more comprehensive characterization of cropland change in China. We use GlobeLand30-a global land cover dataset with a 30 m resolution for the years 2000 and 2010-and characterize changes in TA and NP for each county as increase, stable, or decrease. This characterization shows that 703 out of 2420 counties experienced both cropland loss and increased fragmentation. The predominant cropland loss in these areas, especially in the North China Plain, is converted to artificial land. Another 212 are characterized by the opposite developments: an increase in cropland and decreased fragmentation. These counties, are mainly characterized by a conversion of forest areas and grassland areas. It suggests that the cropland conservation policy in China effectively protected the total cropland area in overall, but the consequences in terms of fragmentation might be underestimated. Counties with no obvious change in both indicators, measuring 279 counties, are mainly located in the Southeast. Our results are further compared with local level case studies: the fair consistency indicates alternatives of applying GlobeLand30 for analyzing landscape changes across scales and for cross-site comparisons.

Multidetector CT (MD-CT) in the diagnosis of uncertain open globe injuries

Energy Technology Data Exchange (ETDEWEB)

Hoffstetter, P.; Schreyer, A.G.; Jung, E.M.; Heiss, P.; Zorger, N. [Inst. fuer Roentgendiagnostik, Universitaetsklinikum Regensburg (Germany); Schreyer, C.I.; Framme, C. [Klink und Poliklinik fuer Augenheilkunde, Universitaetsklinikum Regensburg (Germany)

2010-02-15

Purpose: To evaluate the significance of multislice CT for the diagnosis of uncertain penetrating globe injuries. Materials and Methods: Based on a retrospective chart review between 2002 and 2007, we identified 59 patients presenting with severe ocular trauma with uncertain rupture of the globe due to massive subconjunctival and/or anterior chamber hemorrhage. The IOP (intraocular pressure) was within normal range in all patients. High resolution multidetector CT (MD-CT) scans (16 slice scans) with axial and coronar reconstructions were performed in all patients. The affected eye was examined for signs of penetrating injury such as abnormal eye shape, scleral irregularities, lens dislocation or intravitreal hemorrhages. Four experienced radiologists read the CT scans independently. Beside the diagnosis, the relevant morphological criteria and the optimal plane orientation (axial or coronar) were specified. The sensitivity, specificity, and negative and positive predictive value were calculated. Additionally the interobserver variability was determined by applying the Cohen's kappa test. Surgical sclera inspections were performed in all cases as a standard of reference. The evaluations of the CT examination were compared with the surgery reports. Results: 59 patients were evaluated (42 men, 17 women). The mean age was 29 years (range 7-91). In 17 patients a rupture of the globe was diagnosed during surgery. 12 of these 17 penetrating injuries (70.6%) were classified correctly by MDCT, 5 of the 17 (29.4%) were not detectable. 42 patients did not have an open globe injury. 41 of these patients were diagnosed correctly negative by MDCT, and one patient was classified false positive. This results in a sensitivity of 70% with a specificity of 98%. There was high inter-rater agreement with kappa values between 0.89-0.96. Most discrepancies were caused by wrong negative findings. The most frequent morphologic criteria for open globe injury were the deformation (n

Globalisation or Journay into the Second Discovery of the Globe

OpenAIRE

Rodin, Davor

2003-01-01

The author claims that the globe was discovered by courageous adventurers and visionaries who had trust in geographical utopia that the Earth was round so they plunged into the unknown in their wretched sailboats. This stage ended in foundation of huge colonial empires but, eventually, this kind of violent colonization failed. What has been left from the first discovery of the globe? The most important reminder is discovery of identities of the former colonized peoples as well as the identity...

Dagik Earth: A Digital Globe Project for Classrooms, Science Museums, and Research Institutes

Science.gov (United States)

Saito, A.; Tsugawa, T.

2017-12-01

Digital globe system is a powerful tool to make the audiences understand phenomena on the Earth and planets in intuitive way. Geo-cosmos of Miraikan, Japan uses 6-m spherical LED, and is one of the largest systems of digital globe. Science on a Sphere (SOS) by NOAA is a digital globe system that is most widely used in science museums around the world. These systems are so expensive that the usage of the digital globes is mainly limited to large-scale science museums. Dagik Earth is a digital globe project that promotes educational programs using digital globe with low cost. It aims to be used especially in classrooms. The cost for the digital globe of Dagik Earth is from several US dollars if PC and PC projector are available. It uses white spheres, such as balloons and balance balls, as the screen. The software is provided by the project with free of charge for the educational usage. The software runs on devices of Windows, Mac and iOS. There are English and Chinese language versions of the PC software besides Japanese version. The number of the registered users of Dagik Earth is about 1,400 in Japan. About 60% of them belongs to schools, 30% to universities and research institutes, and 8% to science museums. In schools, it is used in classes by teachers, and science activities by students. Several teachers have used the system for five years and more. In a students' activity, Dagik Earth contents on the typhoon, solar eclipse, and satellite launch were created and presented in a school festival. This is a good example of the usage of Dagik Earth for STEM education. In the presentation, the system and activity of Dagik Earth will be presented, and the future expansion of the project will be discussed.

Openwebglobe - AN Open Source Sdk for Creating Large-Scale Virtual Globes on a Webgl Basis

Science.gov (United States)

Loesch, B.; Christen, M.; Nebiker, S.

2012-07-01

This paper introduces the OpenWebGlobe project (www.openwebglobe.org) and the OpenWebGlobe SDK (Software Development Kit) - an open source virtual globe environment using WebGL. Unlike other (web-based) 3d geovisualisation technologies and toolkits, the OpenWebGlobe SDK not only supports the content authoring and web visualization aspects, but also the data processing functionality for generating multi-terabyte terrain, image, map and 3d point cloud data sets in high-performance and cloud-based parallel computing environments. The OpenWebGlobe architecture is described and the paper outlines the processing and the viewer functionality provided by the OpenWebGlobe SDK. It then discusses the generation and updating of a global 3d base map using OpenStreetMap data and finally presents two show cases employing the technology a) for implementing an interactive national 3d geoportal incorporating high resolution national geodata sets and b) for implementing a 3d geoinformation service supporting the real-time incorporation of 3d point cloud data.

Two-point resistance of a resistor network embedded on a globe.

Science.gov (United States)

Tan, Zhi-Zhong; Essam, J W; Wu, F Y

2014-07-01

We consider the problem of two-point resistance in an (m-1) × n resistor network embedded on a globe, a geometry topologically equivalent to an m × n cobweb with its boundary collapsed into one single point. We deduce a concise formula for the resistance between any two nodes on the globe using a method of direct summation pioneered by one of us [Z.-Z. Tan, L. Zhou, and J. H. Yang, J. Phys. A: Math. Theor. 46, 195202 (2013)]. This method is contrasted with the Laplacian matrix approach formulated also by one of us [F. Y. Wu, J. Phys. A: Math. Gen. 37, 6653 (2004)], which is difficult to apply to the geometry of a globe. Our analysis gives the result in the form of a single summation.

GIS Function Coupling for Virtual Globes, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — Virtual Globe (VG) systems such as Google Earth, NASA World Winds and Microsoft Virtual Earth provide captivating animated 3D visualizations and support user queries...

[Relationship between cocaine dependence treatment and personal values of openness to change and conservation].

Science.gov (United States)

Galdós, Jesús Saiz; Sánchez, Isabel Martínez

2010-01-01

To analyze the relationship between participation in a drug addiction treatment program and Schwartz's values of Openness to change (Self-direction, Stimulation and Hedonism) and Conservation (Tradition, Conformity and Security) in cocaine users. The present quasi-experimental study was carried out on a sample of 411 adult cocaine users, grouped according to whether they had begun treatment more than three months earlier or less than three months earlier or they were not receiving any treatment. Using Schwartz's Personal Values Questionnaire (PVQ), we measured the priority given by each of these groups to the values of Conservation and Openness to change. Participants who had initiated the treatment more than three months earlier tended to score lower in the values of Openness to change than those who were not in treatment, though there were no significant differences in these values between those who were not in treatment and those who had been in treatment for less than three months. On the other hand, it was observed that participants in treatment, regardless of the time spent in treatment, scored higher in values of Conservation than the cocaine users who were not in treatment. These results reveal the relationship between attendance on a cocaine-dependence treatment program and personal values, together with their potential importance in treatment and rehabilitation programs for cocaine users.

[Bladder-conserving treatment for bladder cancer: potential of and developments in radiotherapy].

Science.gov (United States)

Hulshof, Maarten C C M; Pieters, Bradley R; Koning, Caro C E

2013-01-01

The standard treatment for muscle-invasive bladder cancer is surgical removal of the bladder and construction of a neobladder. Recently, important improvements have been made in the potential for bladder-conserving treatment using radiotherapy. External beam radiotherapy has undergone technological improvements, as a result of which it is possible to radiate the tumour more precisely while decreasing radiation to healthy tissue. Radiochemotherapy improves local recurrence-free and overall survival compared with radiotherapy alone. The results of this combined treatment are comparable with those of surgery. Additionally, Dutch radiotherapy departments have collected data in a national database of 1040 selected patients with confined bladder cancer. These patients were treated with external beam radiation, limited surgery and brachytherapy. The 5-year local recurrence-free survival was 75%. Bladder conserving treatment options for muscle-invasive bladder cancer should be discussed during the multidisciplinary meeting.

Percutaneous vertebroplasty and conservative management for the treatment of osteoporotic vertebral fractures: a comparative study

International Nuclear Information System (INIS)

Liu Wengui; Lu Jinyu; Sun Jianhua; Liang Ding; Li Zhiwei; Wang Hesheng; Guo Shanfeng

2011-01-01

Objective: To investigate the better therapeutic measures for painful osteoporotic vertebral compression fractures (OVCF) through comparing the efficacy of percutaneous vertebroplasty (PVP) with that of conservative management. Methods: Forty-three consecutive patients, encountered from December 2009 to December 2010 in authors' hospital, were enrolled in this study. The patients were divided into PVP group (n=22) and conservative group (n=21). Visual analog score (VAS) for pain and Oswestry disability index (ODI) questionnaire scores were assessed before and 1 week, 1, 3, 6, 12 months after the treatment. Patients' activity levels and other information, including complications and new fractures after treatment, were also evaluated. Results: Before the treatment both the VAS and ODI scores showed no statistically significant difference between the two groups. Significant reduction of both VAS and ODI was observed in PVP group at 1 week and at 1 and 3 months after treatment when compared with those in conservative group (P<0.05). Patients' activity levels in PVP group were significantly improved than that in conservative group (P<0.01). One new fracture was observed in the conservative group, while no new fracture was seen in the PVP group. Conclusion: Immediate pain relief and improvement of daily activities after PVP can be achieved in all patients. PVP should be considered as the treatment of first choice for symptomatic osteoporotic vertebral fractures. (authors)

Traumatic Globe Subluxation and Intracranial Injury Caused by Bicycle Brake Handle

OpenAIRE

Poroy; Cibik; Yazici

2016-01-01

Introduction Penetration of a bicycle brake handle into the orbit is a rare and serious type of trauma. Globe subluxation due to such trauma has not been previously reported. Case Presentation A 10-year-old girl presented after falling from a bicycle, which resulted in the handbrake penetrating her right upper eyelid. On examination, the globe was subluxated anteriorly, there was no light perception, and the pupilla was fixed and ...

The CinéGlobe film festival opens at CERN and the Forum Meyrin theatre

CERN Multimedia

CERN Bulletin

2010-01-01

The second edition of CinéGlobe, the international festival of short films and science documentaries, will be held from 16 to 20 February 2010. It is being organised by the club Open Your Eyes Films, CERN and the culture office of the city of Meyrin. For five days, 80 films from amongst the 700 submissions will be shown at the Globe of Science and Innovation and in the Forum Meyrin theatre. On Saturday, 20 February 2010, a jury composed of film professionals and public figures will award a Golden CinéGlobe for the best film in each category, along with an audience award, at a ceremony in the Globe of Science and Innovation. The festival programme is available for download. See you at the movies!

Interactive Visualization and Analysis of Geospatial Data Sets - TrikeND-iGlobe

Science.gov (United States)

Rosebrock, Uwe; Hogan, Patrick; Chandola, Varun

2013-04-01

The visualization of scientific datasets is becoming an ever-increasing challenge as advances in computing technologies have enabled scientists to build high resolution climate models that have produced petabytes of climate data. To interrogate and analyze these large datasets in real-time is a task that pushes the boundaries of computing hardware and software. But integration of climate datasets with geospatial data requires considerable amount of effort and close familiarity of various data formats and projection systems, which has prevented widespread utilization outside of climate community. TrikeND-iGlobe is a sophisticated software tool that bridges this gap, allows easy integration of climate datasets with geospatial datasets and provides sophisticated visualization and analysis capabilities. The objective for TrikeND-iGlobe is the continued building of an open source 4D virtual globe application using NASA World Wind technology that integrates analysis of climate model outputs with remote sensing observations as well as demographic and environmental data sets. This will facilitate a better understanding of global and regional phenomenon, and the impact analysis of climate extreme events. The critical aim is real-time interactive interrogation. At the data centric level the primary aim is to enable the user to interact with the data in real-time for the purpose of analysis - locally or remotely. TrikeND-iGlobe provides the basis for the incorporation of modular tools that provide extended interactions with the data, including sub-setting, aggregation, re-shaping, time series analysis methods and animation to produce publication-quality imagery. TrikeND-iGlobe may be run locally or can be accessed via a web interface supported by high-performance visualization compute nodes placed close to the data. It supports visualizing heterogeneous data formats: traditional geospatial datasets along with scientific data sets with geographic coordinates (NetCDF, HDF, etc

Open globe injury in Hospital Universiti Sains Malaysia - A 10-year review

Directory of Open Access Journals (Sweden)

Madhusudhan A/L Paramananda

2014-06-01

Full Text Available AIM: To identify the aetiology of open globe injuries at Hospital Universiti Sains Malaysia over a period of 10y and the prognostic factors for visual outcome.METHODS:Retrospective review of medical records of open globe injury cases that presented from January 2000 to December 2009. Classification of open globe injury was based on the Birmingham Eye Trauma Terminology (BETT. Records were obtained with hospital permission via the in-house electronic patient management system, and the case notes of all patients with a diagnosis of open globe injury were scrutinised. Patients with prior ocular trauma, pre-existing ocular conditions affecting the visual acuity, contrast sensitivity, central vision or corneal thickness, as well as those with a history of previous intraocular or refractive surgery were excluded. Analysis of data was with SPSS version 20.0. Ordinal logistic regression analysis was used to examine the association between prognostic factors and visual outcome.RESULTS: This study involved 220 patients (n=222 eyes. The most common place of injury was the home (51.8%, followed by the workplace (23.4%. Among children aged less than 16y of age, domestic-related injury was the predominant cause (54.6%, while in those aged 16y and above, occupational injuries were the most common cause (40.0%. Most eyes (76.5% had an initial visual acuity worse than 3/60, and in half of these, the visual acuity improved. The visual outcome was found to be significantly associated with the initial visual acuity (P<0.005, posterior extent of wound (P<0.001, length of wound (P<0.001, presence of hyphaema (P<0.001 and presence of vitreous prolapse ((P<0.005.CONCLUSION:The most common causes of open globe injury are domestic accidents and occupational injuries. Significant prognostic factors for final visual outcome in patients with open globe injury are initial visual acuity, posterior extent and length of wound, presence of hyphaema and presence of vitreous

[Case control study of fractures-dislocations of ankle joint with conservative and operative treatment].

Science.gov (United States)

Zhang, Song-Tu; Lin, Yi-Rong; Chen, Lian-Yuan

2010-10-01

To compare the clinical efficacy of grade III, IV supination-eversion fractures-dislocations of ankle joint between manipulative treatment and operative treatment. From September 2007 to December 2008, the clinical data of 60 patients with grade III, IV supination-eversion fractures-dislocations of ankle joint were retrospectively analyzed. There were 32 males and 28 females, ranging in age from 18 to 70 years with an average age of 38.17 years. All patients were respectively treated with manipulative treatment (conservative group, 30 cases) and operative treatment (operative group, 30 cases). The joint function was compared with Mazur standard; the reduction and shifting of fractures were observed with X-ray; the hospitalization day and the therapeutic cost were compared between two groups. All patients were followed up with an average of 15.27 months (ranged, 6 to 25 months). In conservative group, 16 cases got excellent result in joint function, 10 good, 3 fair, 1 poor; in operative group, 20 cases got excellent result, 8 good, 2 fair, 0 poor. In conservative group in the X-ray showed 25 cases obtained excellent and good reduction, 4 fair, 1 poor; and in operative group in the X-ray showed 28 cases obtained excellent and good reduction, 2 fair, 0 poor. There was no significant difference at the joint function and X-ray film after treatment between two groups (P > 0.05). The hospital day was respectively (7.87 +/- 3.34), (17.37 +/- 4.64) d in conservative group and operative group; and the therapeutic cost was respectively (2 506.67 +/- 649.10), (11 473.33 +/- 1 564.90) yuan. There was significant difference at hospital day and therapeutic cost between two groups (P fractures and dislocations of ankle joint. However, conservative treatment has advantage of high safety factor, low therapeutic cost, can reduce medical costs for patients.

Outcomes After Conservative, Endoscopic, and Surgical Treatment of Groove Pancreatitis: A Systematic Review.

Science.gov (United States)

Kager, Liesbeth M; Lekkerkerker, Selma J; Arvanitakis, Marianna; Delhaye, Myriam; Fockens, Paul; Boermeester, Marja A; van Hooft, Jeanin E; Besselink, Marc G

2017-09-01

Groove pancreatitis (GP) is a focal form of chronic pancreatitis affecting the paraduodenal groove area, for which consensus on diagnosis and management is lacking. We performed a systematic review of the literature to determine patient characteristics and imaging features of GP and to evaluate clinical outcomes after treatment. Eight studies were included reporting on 335 GP patients with a median age of 47 years (range, 34 to 64 y), with 90% male, 87% smokers, and 87% alcohol consumption, and 47 months (range, 15 to 122 mo) of follow-up. Most patients presented with abdominal pain (91%) and/or weight loss (78%). Imaging frequently showed cystic lesions (91%) and duodenal stenosis (60%).Final treatment was conservative (eg, pain medication) in 29% of patients. Endoscopic treatment (eg, pseudocyst drainage) was applied in 19% of patients-34% of these patients were subsequently referred for surgery. Overall, 59% of patients were treated surgically (eg, pancreatoduodenectomy). Complete symptom relief was observed in 50% of patients who were treated conservatively, 57% who underwent endoscopic treatment, and 79% who underwent surgery. GP is associated with male gender, smoking, and alcohol consumption. The vast majority of patients presents with abdominal pain and with cystic lesions on imaging. Although surgical treatment seems to be the most effective, both conservative and endoscopic treatment are successful in about half of patients. A stepwise treatment algorithm starting with the least invasive treatment options seems advisable.

Results from the Prototype GLOBE at Night Worldwide Light Pollution Observation Program

Science.gov (United States)

Walker, Constance E.; Pompea, S. M.; Isbell, D.; Orellana, D.; Blurton, C.; Henderson, S.

2006-06-01

Students, families, and educators worldwide participated in GLOBE at Night - an international event designed to observe and record the visible stars as a means of measuring light pollution in a given location. Participation was open to anyone - anywhere in the world - who could get outside and look skyward during the week of March 22-29, 2006. Our goal was 5000 observations from around the world in this prototype program.The hands-on learning activities associated with the program were designed to extend the traditional classroom and school day with a week of nighttime observations involving teachers, students and their families. By locating specific constellations in the sky, students from around the world learned how the lights in their community contribute to light pollution. Students explored the different light sources in their community learning the relationship between science, technology and society, and they reported their observations online through a central database allowing for authentic worldwide research and analysis. The observations made during GLOBE at Night helped students and scientists together assess how the quality of the night sky varies around the world as well as the level of energy wastage associated with poorly-shielded lights.For more information, visit http://www.globe.gov/globeatnight.GLOBE at Night is a collaboration between The GLOBE Program, the National Optical Astronomy Observatory (NOAO), Centro de Apoyo a la Didactica de la Astronomia (CADIAS) in Chile , Windows to the Universe, and Environmental Systems Research Institute, Inc. (ESRI).

Conservative treatment of excessive anterior pelvic tilt

DEFF Research Database (Denmark)

Brekke, Anders Falk

of Clinical Research, University of Southern Denmark, Denmark 3Department of Physiotherapy, University College Zealand, Denmark 4Center for Evidence-Based Medicine, Odense University Hospital, Denmark Correspondence Anders Falk Brekke E-mail: afbrekke@health.sdu.dk Mob: +45 7248 2626 Add: Sdr. Boulevard 29......Conservative treatment of excessive anterior pelvic tilt: A systematic review Anders Falk Brekke1,2,3, Søren Overgaard1,2, Asbjørn Hróbjartsson4, Anders Holsgaard-Larsen1,2 1Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Odense University Hospital 2Department...

Planning and Management of Real-Time Geospatialuas Missions Within a Virtual Globe Environment

Science.gov (United States)

Nebiker, S.; Eugster, H.; Flückiger, K.; Christen, M.

2011-09-01

This paper presents the design and development of a hardware and software framework supporting all phases of typical monitoring and mapping missions with mini and micro UAVs (unmanned aerial vehicles). The developed solution combines state-of-the art collaborative virtual globe technologies with advanced geospatial imaging techniques and wireless data link technologies supporting the combined and highly reliable transmission of digital video, high-resolution still imagery and mission control data over extended operational ranges. The framework enables the planning, simulation, control and real-time monitoring of UAS missions in application areas such as monitoring of forest fires, agronomical research, border patrol or pipeline inspection. The geospatial components of the project are based on the Virtual Globe Technology i3D OpenWebGlobe of the Institute of Geomatics Engineering at the University of Applied Sciences Northwestern Switzerland (FHNW). i3D OpenWebGlobe is a high-performance 3D geovisualisation engine supporting the web-based streaming of very large amounts of terrain and POI data.

Using Digital Globes to Explore the Deep Sea and Advance Public Literacy in Earth System Science

Science.gov (United States)

Beaulieu, Stace E.; Emery, Emery; Brickley, Annette; Spargo, Abbey; Patterson, Kathleen; Joyce, Katherine; Silva, Tim; Madin, Katherine

2015-01-01

Digital globes are new technologies increasingly used in informal and formal education to display global datasets and show connections among Earth systems. But how effective are digital globes in advancing public literacy in Earth system science? We addressed this question by developing new content for digital globes with the intent to educate and…

Radical vs. Conservative Surgical Treatment of Hepatic Hydatid Cyst: A 10- Year Experience

Directory of Open Access Journals (Sweden)

M Ghaemi

2009-07-01

Full Text Available Introduction: Hepatic hydatid cyst is caused by echinococcosis granulosis. It is a major health problem in endemic areas. The modern treatment of hydatid cysts of the liver varies from surgical intervention to percutaneous drainage or medical therapy. A high rate of complications following percutaneous drainage, and ineffectiveness of medical therapy have shown not to be the definitive treatments for the disease. Thus, surgery is still the best choice for the treatment of hydatid cyst of the liver. Surgical treatment methods can be divided into radical and conservative approaches. There is controversy regarding efficacy of the two surgical methods. In this study, we aimed to present a retrospective evaluation of the two surgical methods in patients treated for the hepatic hydatid cyst. Methods: This retrospective study reviewed medical records of 135 patients who underwent surgery for hepatic hydatid cyst from 1997 to 2007. Surgery comprised conservative methods (evacuation of the cyst content and excision of the inner cyst layers and radical methods (total excision of the cyst and removal of its outer layer. Results: One hundred thirty five patients underwent liver surgery. Conservative surgery was performed for 71 (53%, whereas, the remaining 64 patients (47% underwent radical surgery. Postoperative complications were 28% and 19%, respectively. Recurrence of the cyst in the conservative and radical surgery groups was noted to be 12.5 and 1.5%, respectively. The mean length of hospital stay was shorter in the radical surgery group (5 vs. 15 days. Conclusion: Radical surgery may be the preferred treatment for the hepatic hydatid cyst because of its low rate of postoperative complications and recurrence, as well as short hospital stay. Selection of the most appropriate treatment depends on the size, number, and location of the cyst(s, and presence of cystobiliary communications, and the availability of an experienced surgeon.

The new Globe car park: for visitors and the CERN community

CERN Multimedia

2014-01-01

With twice as many parking spaces as the existing car park by the flagpoles and the same conditions of use (see here), the new Globe car park will be open for use from Monday 5 May.   The new Globe car park: the blue spaces are reserved for P+R pass holders. The new car park, which will be inaugurated on Monday 28 April by CERN’s Director-General in the presence of officials representing the Canton of Geneva and the sub-prefecture of the Ain, will better cater to the needs of CERN’s many visitors. The large number of spaces (around 100) reserved for P+R users will encourage the use of public transport, which will be particularly important at peak times. From autumn 2014, the Globe car park will completely replace the flagpole car park, where the new Esplanade des Particules will be built.

The Globe of Science and Innovation at dawn

CERN Multimedia

Maximilien Brice

2006-01-01

CERN's exhibition centre 'the Globe of Science and Innovation' is seen just after sunrise. This wooden building was given to CERN in 2004 as a gift from the Swiss Confederation to mark 50 years since the Organisation's foundation.

Reincarnation platn of globe. Chikyu saisei keikaku ni tsuite

Energy Technology Data Exchange (ETDEWEB)

Matsuyama, T. (Agency of Natural Resources and Energy, Tokyo (Japan))

1990-11-30

The period of 200 years since the Industrial Revolution has taken for the occurence of global warming up problem, and it may require to face the problem comprehensively and for long period of 100 years unit to resolve it. This reincarnation plan of globe aims to reincarnate the changed global environment hereafter by using time of about 100 years, and proposes to make the comprehensive and long term actions to suppress and reduce exhaust gases resulting the greenhouse effect by the cooperation of all nations in the world. In the former 50 years, feasible countermeasures such as deepenung of scientific knowkedges, promotion of worldwide energy saving, introduction of clean energy, development of revolutional environmental technology, expansion of CO {sub 2} absorbing sources, and technological development of energy for the next generation will be executed continuously. In the latter 50 years, the gas exhausting amount resulting the green house effect will be reduced and suppressed from these results. Owing to these measures, the reduction of gas resulting the greenhouse effect which exceeds the expectation, can clean the globe after 100 years because the cleaning results will be incorporated into the natural circulation and the green globe will be reincarnated. 1 fig., 1 tab

The Globe of Science and Innovation at night

CERN Multimedia

Maximilien Brice

2005-01-01

The Globe of Science and Innovation, CERN's exhibition centre is seen lit up at night. This wooden building was given to CERN in 2004 as a gift from the Swiss Confederation to mark 50 years since the Organization's foundation.

The effect of credentialism on the cost of conservation treatment

DEFF Research Database (Denmark)

Brajer, Isabelle Eve

2017-01-01

This paper focuses on the economic cost of treatment of cultural heritage using conservation of wall paintings in Danish churches over its entire period, from 1855 to 2015, as a primary data source. Financial costs for 990 individual projects harvested from archival documents were adjusted with s...

Global sea turtle conservation successes.

Science.gov (United States)

Mazaris, Antonios D; Schofield, Gail; Gkazinou, Chrysoula; Almpanidou, Vasiliki; Hays, Graeme C

2017-09-01

We document a tendency for published estimates of population size in sea turtles to be increasing rather than decreasing across the globe. To examine the population status of the seven species of sea turtle globally, we obtained 299 time series of annual nesting abundance with a total of 4417 annual estimates. The time series ranged in length from 6 to 47 years (mean, 16.2 years). When levels of abundance were summed within regional management units (RMUs) for each species, there were upward trends in 12 RMUs versus downward trends in 5 RMUs. This prevalence of more upward than downward trends was also evident in the individual time series, where we found 95 significant increases in abundance and 35 significant decreases. Adding to this encouraging news for sea turtle conservation, we show that even small sea turtle populations have the capacity to recover, that is, Allee effects appear unimportant. Positive trends in abundance are likely linked to the effective protection of eggs and nesting females, as well as reduced bycatch. However, conservation concerns remain, such as the decline in leatherback turtles in the Eastern and Western Pacific. Furthermore, we also show that, often, time series are too short to identify trends in abundance. Our findings highlight the importance of continued conservation and monitoring efforts that underpin this global conservation success story.

Uurimuslik õpe GLOBE programmi näitel / Imbi Henno

Index Scriptorium Estoniae

Henno, Imbi

2005-01-01

Artiklis tutvustatakse põhi- ja keskkooliõpilastele mõeldud uurimuslikku õpet ja praktilisi tegevusi pakkuvat keskkonnasuunitlusega ülemaailmset haridus- ja teadusprogrammi GLOBE (Global Learning and Observations to Benefit Environment)

Randomised controlled trial of prophylactic antibiotic treatment for the prevention of endophthalmitis after open globe injury at Groote Schuur Hospital.

Science.gov (United States)

Du Toit, N; Mustak, S; Cook, C

2017-07-01

Most post-traumatic acute infectious endophthalmitis occur within a week of open globe trauma, necessitating early antibiotic prophylaxis. There are few randomised studies that demonstrate the benefits of prophylactic antibiotics. This randomised controlled non-inferiority trial was aimed at determining the incidence of post-traumatic endophthalmitis using established intravenous/oral prophylaxis and comparing this to the incidence using oral antibiotics only. All adult patients admitted with open globe injury were included. Those with proven endophthalmitis, high-risk features, who underwent primary evisceration and those allergic to the trial antibiotics were excluded. Patients were randomised to receive either intravenous cefazolin and oral ciprofloxacin or oral ciprofloxacin and oral cefuroxime for 3 days from admission. Acute endophthalmitis was the primary outcome. Patients completed the study if they were followed up for 6 weeks post injury. Three hundred patients were enrolled, with 150 in each arm. There were 99 exclusions. Seven patients developed endophthalmitis despite prophylaxis-2.0% (three cases) in the intravenous and oral arm, compared with 2.7% (four cases) in the oral-only arm-this difference was not statistically significant ( p=0.703). The incidence of endophthalmitis with prophylaxis was 2-3%. Selected patients with open globe injuries (without high-risk features) may receive either intravenous cefazolin and oral ciprofloxacin, or oral cefuroxime and oral ciprofloxacin as prophylaxis against acute endophthalmitis-the latter regimen has the advantage of shortening patients' hospital stays and reducing costs. Non-inferiority study-design limitations should be taken into account, however. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Voices from Around the Globe

Directory of Open Access Journals (Sweden)

Birgit Schreiber

2017-07-01

Full Text Available JSAA has been seeking to provide an opportunity for Student Affairs professionals and higher education scholars from around the globe to share their research and experiences of student services and student affairs programmes from their respective regional and institutional contexts. This has been given a specific platform with the guest-edited issue “Voices from Around the Globe” which is the result of a collaboration with the International Association of Student Affairs and Services (IASAS, and particularly with the guest editors, Kathleen Callahan and Chinedu Mba.

Observations of El Niño impacts using in situ GLOBE protocols and satellite data

Science.gov (United States)

Srinivasan, M. M.; Destaerke, D.

2015-12-01

The El Niño phenomenon is a periodic ocean condition that occurs every two to ten years in the central and east-central equatorial Pacific Ocean. It alters the normal patterns of ocean circulation, surface temperature, and evaporation, causing noticeable and often severe changes in weather conditions in many areas of the world. El Niño is the warm phase of the El Niño Southern Oscillation (ENSO), and usually reaches its peak between December and February time period. El Niño and its worldwide consequences are studied by the school network of the GLOBE Program (www.globe.gov) which brings together students, teachers, and scientists in support of student research and validation of international Earth science research projects. Since the start of the GLOBE Program over 20 years ago, GLOBE classrooms utilize carefully developed daily, weekly, or seasonally protocols such as maximum, minimum and current temperatures, rainfall, soil moisture, and others, to measure changes in the environment. The data collected by the students is entered in an online GLOBE database. In addition to the student-contributed data, automated stations also collect and send measurements to the GLOBE database.Students compare their data with global data acquired by satellites to help validate the satellite data. With a potentially historic-level El Niño event thought to be on the horizon--possibly one of the strongest in 50 years—we will propose an emphasis on measurements from GLOBE schools that will support studies and satellite observations of El Niño. We plan to provide the schools with additional satellite data sets such as ocean temperature measurements from Advanced Very High Resolution Radiometer (AVHRR), sea surface elevation measurements from Jason-2 and 3 (after it launches), and others to be identified. We wish to address and support the following educational objectives: - Demonstrate how El Niño affects local precipitation and temperature across the globe, - Link teachers

New cropping designs for globe artichoke industry

Directory of Open Access Journals (Sweden)

Rosario Paolo Mauro

2011-03-01

Full Text Available A two-year experiment was carried-out in order to evaluate the effects of two plant arrangements (single vs. twin rows and four plant densities (1.0 -1.2 -1.4 and 1.8 plant m–2 on the agronomical behaviour and head characteristics of three globe artichoke genotypes (Violetto di Sicilia, Harmony F1 and Madrigal F1. The change of the cultivation format toward a high density stand significantly increase yield and yield synchronicity. The twin rows plant arrangement, although reduced total yield, increased the yield synchronicity. Moreover, the cultivation of seed-propagated genotypes (Harmony F1 and Madrigal F1 allowed extending significantly the availability of the heads across the year. On the basis of our results, we can assert that the implementation of a specific scheduling cultivation, based on higher density stands, twin rows plant arrangement and the integration of the traditional early genotypes with the new seed-propagated cultivars, is a promising way to match the requirements of a globe artichoke industrial crop, and to predispose a better mechanization of the cultural practices.

Individualism–Collectivism in Hofstede and GLOBE

OpenAIRE

Paul Brewer; Sunil Venaik

2011-01-01

This paper examines the Individualism–Collectivism (I-C) dimension of national culture in the Hofstede and GLOBE models. We identify major contradictions between the two culture models, which result in contradictory relationships with external variables such as economic prosperity. We critically evaluate the content validity of the items used to measure this construct in both models. Based on our analysis, we suggest that Hofstede's Individualism–Collectivism index be relabelled as Self-orien...

Scoliosis in patients with Prader Willi Syndrome – comparisons of conservative and surgical treatment

Directory of Open Access Journals (Sweden)

Goodall Deborah

2009-05-01

Full Text Available Abstract In children with Prader Willi syndrome (PWS, besides growth hormone (GH therapy, control of the food environment and regular exercise, surgical treatment of scoliosis deformities seems the treatment of choice, even though the risks of spinal surgery in this specific population is very high. Therefore the question arises as to whether the risks of spinal surgery outweigh the benefits in a condition, which bears significant risks per se. The purpose of this systematic review of the Pub Med literature was to find mid or long-term results of spinal fusion surgery in patients with PWS, and to present the conservative treatment in a case study of nine patients with this condition. Methods Types of studies included; all kinds of studies; retrospective and prospective ones, which reported upon the outcome of scoliosis surgery in patients with PWS. Types of participants included: patients with scoliosis and PWS. Type of intervention: surgery. Search strategy for identification of the studies; Pub Med; limited to English language and bibliographies of all reviewed articles. Nine patients with PWS from our data-base treated conservatively have been found, being 19 years or over at the time this study has been performed. The results of conservative management are described and related to the natural history and treatment results found in the Pub Med review. Results From 2210 titles displayed in the Pub Med database with the key word being "Prader Willi syndrome", 5 different papers were displayed at the date of the search containing some information on the outcome of surgery and none appeared to contain a mid or long-term follow-up. The PWS patients treated conservatively from our series all stayed below 70° and some of which improved. Discussion If the curve of scoliosis patients with PWS can be kept within certain limits (usually below 70 degrees conservatively, this treatment seems to have fewer complications than surgical treatments. The

WYSIWYG GEOPROCESSING: COUPLING SENSOR WEB AND GEOPROCESSING SERVICES IN VIRTUAL GLOBES

Directory of Open Access Journals (Sweden)

X. Zhai

2012-08-01

Full Text Available We propose to advance the scientific understanding and applications of geospatial data by coupling Sensor Web and Geoprocessing Services in Virtual Globes for higher-education teaching and research. The vision is the concept of "What You See is What You Get" geoprocessing, shortly known as WYSIWYG geoprocessing. Virtual Globes offer tremendous opportunities, such as providing a learning tool to help educational users and researchers digest global-scale geospatial information about the world, and acting as WYSIWYG platforms, where domain experts can see what their fingertips act in an interactive three-dimensional virtual environment. In the meantime, Sensor Web and Web Service technologies make a large amount of Earth observing sensors and geoprocessing functionalities easily accessible to educational users and researchers like their local resources. Coupling Sensor Web and geoprocessing Services in Virtual Globes will bring a virtual learning and research environment to the desktops of students and professors, empowering them with WYSIWYG geoprocessing capabilities. The implementation combines the visualization and communication power of Virtual Globes with the on-demand data collection and analysis functionalities of Sensor Web and geoprocessing services, to help students and researchers investigate various scientific problems in an environment with natural and intuitive user experiences. The work will contribute to the scientific and educational activities of geoinformatic communities in that they will have a platform that are easily accessible and help themselves perceive world space and perform live geoscientific processes.

Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe

Directory of Open Access Journals (Sweden)

Alexandra S. Rashedi

2017-06-01

Full Text Available Purpose: Oncofertility focuses on providing fertility and endocrine-sparing options to patients who undergo life-preserving but gonadotoxic cancer treatment. The resources needed to meet patient demand often are fragmented along disciplinary lines. We quantify assets and gaps in oncofertility care on a global scale. Methods: Survey-based questionnaires were provided to 191 members of the Oncofertility Consortium Global Partners Network, a National Institutes of Health–funded organization. Responses were analyzed to measure trends and regional subtleties about patient oncofertility experiences and to analyze barriers to care at sites that provide oncofertility services. Results: Sixty-three responses were received (response rate, 25%, and 40 were analyzed from oncofertility centers in 28 countries. Thirty of 40 survey results (75% showed that formal referral processes and psychological care are provided to patients at the majority of sites. Fourteen of 23 respondents (61% stated that some fertility preservation services are not offered because of cultural and legal barriers. The growth of oncofertility and its capacity to improve the lives of cancer survivors around the globe relies on concentrated efforts to increase awareness, promote collaboration, share best practices, and advocate for research funding. Conclusion: This survey reveals global and regional successes and challenges and provides insight into what is needed to advance the field and make the discussion of fertility preservation and endocrine health a standard component of the cancer treatment plan. As the field of oncofertility continues to develop around the globe, regular assessment of both international and regional barriers to quality care must continue to guide process improvements.

Optimizing Conservation Strategies for a Threatened Tree Species: In Situ Conservation of White Ash (Fraxinus americana L. Genetic Diversity through Insecticide Treatment

Directory of Open Access Journals (Sweden)

Charles E. Flower

2018-04-01

Full Text Available Forest resources face numerous threats that require costly management. Hence, there is an increasing need for data-informed strategies to guide conservation practices. The introduction of the emerald ash borer to North America has caused rapid declines in ash populations (Fraxinus spp. L.. Natural resource managers are faced with a choice of either allowing ash trees to die, risking forest degradation and reduced functional resilience, or investing in conserving trees to preserve ecosystem structure and standing genetic diversity. The information needed to guide these decisions is not always readily available. Therefore, to address this concern, we used eight microsatellites to genotype 352 white ash trees (Fraxinus americana L. across 17 populations in the Allegheny National Forest; a subset of individuals sampled are part of an insecticide treatment regimen. Genetic diversity (number of alleles and He was equivalent in treated and untreated trees, with little evidence of differentiation or inbreeding, suggesting current insecticidal treatment is conserving local, neutral genetic diversity. Using simulations, we demonstrated that best practice is treating more populations rather than more trees in fewer populations. Furthermore, through genetic screening, conservation practitioners can select highly diverse and unique populations to maximize diversity and reduce expenditures (by up to 21%. These findings will help practitioners develop cost-effective strategies to conserve genetic diversity.

Treatment of cooling appliances. Interrelations between environmental protection, resource conservation, and recovery rates

International Nuclear Information System (INIS)

Laner, David; Rechberger, Helmut

2007-01-01

The treatment of cooling appliances in Austria is primarily influenced by two factors. On the one hand is their changing composition and on the other hand the ordinance on Waste Prevention, Collection and Treatment of Waste Electrical and Electronic Equipment (WEEE ordinance), which stipulates a minimum recycling rate of 75% for cooling appliances. This paper investigates whether this recycling rate leads to optimal treatment practices for cooling appliances with respect to resource conservation and environmental protection. Two different treatment technologies which achieve recycling rates between 50-60% and 80-90%, respectively, are compared both for cooling appliances containing Chlorofluorocarbons (CFCs) and for appliances containing Volatile Organic Compounds (VOC). Materials and energy balances are developed for each model. To evaluate resource consumption, expenditures as well as savings of energy and materials are incorporated via the Cumulative Energy Demand (CED). In order to analyse the environmental impact of the different practices, balances for CFC, CO 2 , HF, HCl and solid residues are established. The results show that the treatment type aiming for a maximum of materials recycling contributes more to resource conservation than the other treatment type. But for CFC appliances the former is associated with substantial CFC emissions, which turn out to be most relevant when treating these appliances. Generally, it is found that the optimum recycling rate is a function of the composition of the appliance and the technologies applied, both in recycling and in primary production. A high recycling rate per se does not automatically result in an optimal solution with regard to resource conservation and environmental protection. (author)

Vital tooth with periapical lesion: spontaneous healing after conservative treatment

Directory of Open Access Journals (Sweden)

Hyun-Joo Kim

2012-05-01

Full Text Available It is often presumed that apical periodontitis follows total pulp necrosis, and consequently root canal treatment is commonly performed. Periapical lesion development is usually caused by bacteria and its byproduct which irritate pulp, develop pulpitis, and result in necrosis through an irreversible process. Afterwards, apical periodontitis occurs. This phenomenon is observed as an apical radiolucency in radiographic view. However, this unusual case presents a spontaneous healing of periapical lesion, which has developed without pulp necrosis in a vital tooth, through conservative treatment.

Effects of rocuronium bromide on globe position and respiratory function in isoflurane-anesthetized dogs: a comparison between three different dosages.

Science.gov (United States)

Briganti, Angela; Barsotti, Giovanni; Portela, Diego A; Di Nieri, Camilla; Breghi, Gloria

2015-03-01

To evaluate the effect on globe position and respiration of three dosages of intravenous rocuronium in isoflurane-anesthetized dogs. Thirty-two dogs anesthetized for ophthalmic procedures. The dogs were divided into four groups, each of eight animals (G1-G4). G1, G2, G3 received 0.075, 0.05, 0.03 mg/kg of IV rocuronium, respectively; G4 received 0.9% NaCl IV; all the treatments were administered when an end-tidal isoflurane of 1.1-1.2% was reached. Anesthesia was obtained with dexmedetomidine (2.5 mcg/kg IV), methadone (0.1 mg/kg IV), propofol (2 mg/kg IV), and isoflurane in oxygen. Neuromuscular function was assessed with acceleromyography by stimulation of the peroneal nerve using the train-of-four (ToF) and the ToF ratio (ToFR). Monitoring of cardiovascular and respiratory functions was performed. Changes in globe position were recorded. All three dosages of rocuronium produced centralization of the globe. Duration was 24.3 ± 4.2, 23.4 ± 3.6, and 8.7 ± 2.8 min, for G1, G2, and G3, respectively. The control group did not show globe centralization. No significant differences were found among the four groups in cardiovascular and respiratory parameters. Minute volume and ToFR were significantly lower in G1 compared with baseline values. All doses of rocuronium resulted in globe centralization. The higher dose provoked a transient respiratory depression and some degree of skeletal muscular blockade detectable with ToFR. No alterations in respiratory activity were present when 0.05 mg/kg was used. The 0.03 mg/kg dosage could be useful for very short ophthalmic procedures. © 2013 American College of Veterinary Ophthalmologists.

Crowd-Sourcing with K-12 citizen scientists: The Continuing Evolution of the GLOBE Program

Science.gov (United States)

Murphy, T.; Wegner, K.; Andersen, T. J.

2016-12-01

Twenty years ago, the Internet was still in its infancy, citizen science was a relatively unknown term, and the idea of a global citizen science database was unheard of. Then the Global Learning and Observations to Benefit the Environment (GLOBE) Program was proposed and this all changed. GLOBE was one of the first K-12 citizen science programs on a global scale. An initial large scale ramp-up of the program was followed by the establishment of a network of partners in countries and within the U.S. Now in the 21st century, the program has over 50 protocols in atmosphere, biosphere, hydrosphere and pedosphere, almost 140 million measurements in the database, a visualization system, collaborations with NASA satellite mission scientists (GPM, SMAP) and other scientists, as well as research projects by GLOBE students. As technology changed over the past two decades, it was integrated into the program's outreach efforts to existing and new members with the result that the program now has a strong social media presence. In 2016, a new app was launched which opened up GLOBE and data entry to citizen scientists of all ages. The app is aimed at fresh audiences, beyond the traditional GLOBE K-12 community. Groups targeted included: scouting organizations, museums, 4H, science learning centers, retirement communities, etc. to broaden participation in the program and increase the number of data available to students and scientists. Through the 20 years of GLOBE, lessons have been learned about changing the management of this type of large-scale program, the use of technology to enhance and improve the experience for members, and increasing community involvement in the program.

Comparison of surgical treatment with direct repair versus conservative treatment in young patients with spondylolysis: a prospective, comparative, clinical trial.

Science.gov (United States)

Lee, Gun Woo; Lee, Sun-Mi; Ahn, Myun-Whan; Kim, Ho-Joong; Yeom, Jin S

2015-07-01

Although direct repair (DR) with screw fixation at the pars defect is a common surgical treatment for lumbar spondylolysis, it is unknown whether DR leads to better outcomes for young patients with spondylolysis than traditional nonsurgical treatment. The purpose of the study was to investigate whether DR was associated with better outcomes for lumbar spondylolysis in young patients than traditional conservative treatment. This is a prospective cohort study. Of 1,784 patients with low back pain in the reference period, 149 young patients with spondylolysis who followed up for at least 1 year were enrolled in the study. The primary outcome was pain intensity at the lower back measured with a Visual Analog Scale. Secondary outcomes included the functional outcome as measured with the Oswestry disability index (ODI) and the 12-item short-form health survey (SF-12) consisting of the physical component summary (PCS) and mental component summary (MCS) scores, the radiologic outcome as measured with lumbar spine radiographs and computed tomography scans, and complications of treatment. This was a prospective comparative study between two groups of patients who were treated with either conservative treatment or surgery for lumbar spondylolysis. Enrolled patients self-selected their own treatment and were allocated to either the traditional care group with conservative treatment (87 patients) or the surgery group (62 patients). All patients were followed up for at least 1 year. Pain intensity at the lower back did not differ significantly between groups at the final follow-up. Likewise, the ODI and SF-12 (PCS and MCS) scores did not differ significantly between groups (p=.13, .71, and .68, respectively). The change in the gap distance of the pars defect at the final follow-up was significantly different between groups (traditional care group: +0.8±0.4 mm; surgery group: -0.7±0.5; p=.01). The union rate at 1 year after surgical treatment was 52% (32/61). The rate of

Citizen Scientist Contributions to Observations Benefiting the Earth through the GLOBE Program

Science.gov (United States)

Chambers, L. H.; Riebeek Kohl, H.; Murphy, A.; Butler, D. M.

2017-12-01

Citizen science has proliferated recently due to widespread use of the internet and mobile devices, but it has a long history (i.e., the Christmas Bird Count). Since the mid-1990s, the GLOBE Program has engaged participants at a global scale. Though initially focused on teachers and students in formal education settings, it quickly attracted interest from the public as well. In 2016, GLOBE formally launched an initiative to widely engage citizen scientists in its 117 countries through release of a mobile app called GLOBE Observer (GO). GO seeks to increase the number and distribution of participants by providing a simple, engaging - and fun - interface to collect and report data. Observations featured in the app are a carefully selected subset of 50+ GLOBE measurement protocols. They must leverage app features, require little to no equipment besides the mobile device, and have scientists or other stakeholders ready to use the data. The app is designed to minimize barriers to participation, but for those who want to do or know more GLOBE also offers on-line training to turn observers into community members with recognized certification in a protocol area. First released was a cloud observation protocol, supporting validation of a variety of Earth imaging sensors. Second was a mosquito habitat mapping protocol, poised to greatly increase the amount and distribution of local data to validate disease forecast models based on remotely sensed conditions, with additional focus on eliminating disease-carrying mosquito breeding sites. Next in development is a land cover protocol to obtain ground truth imagery for the Landsat science team. The app is also being leveraged for quick development of a short-term eclipse mini-app, to be used on August 21st only during the North American eclipse. This app is designed to make it easy for large numbers of people observing the eclipse, throughout North America, to take and record high time resolution observations of cloud cover and

The isolation and mapping of a novel hydroxycinnamoyltransferase in the globe artichoke chlorogenic acid pathway

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Bourgaud Frédéric

2009-03-01

Full Text Available Abstract Background The leaves of globe artichoke and cultivated cardoon (Cynara cardunculus L. have significant pharmaceutical properties, which mainly result from their high content of polyphenolic compounds such as monocaffeoylquinic and dicaffeoylquinic acid (DCQ, and a range of flavonoid compounds. Results Hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase (HQT encoding genes have been isolated from both globe artichoke and cultivated cardoon (GenBank accessions DQ915589 and DQ915590, respectively using CODEHOP and PCR-RACE. A phylogenetic analysis revealed that their sequences belong to one of the major acyltransferase groups (anthranilate N-hydroxycinnamoyl/benzoyltransferase. The heterologous expression of globe artichoke HQT in E. coli showed that this enzyme can catalyze the esterification of quinic acid with caffeoyl-CoA or p-coumaroyl-CoA to generate, respectively, chlorogenic acid (CGA and p-coumaroyl quinate. Real time PCR experiments demonstrated an increase in the expression level of HQT in UV-C treated leaves, and established a correlation between the synthesis of phenolic acids and protection against damage due to abiotic stress. The HQT gene, together with a gene encoding hydroxycinnamoyl-CoA:shikimate/quinate hydroxycinnamoyltransferase (HCT previously isolated from globe artichoke, have been incorporated within the developing globe artichoke linkage maps. Conclusion A novel acyltransferase involved in the biosynthesis of CGA in globe artichoke has been isolated, characterized and mapped. This is a good basis for our effort to understand the genetic basis of phenylpropanoid (PP biosynthesis in C. cardunculus.

The isolation and mapping of a novel hydroxycinnamoyltransferase in the globe artichoke chlorogenic acid pathway

Science.gov (United States)

Comino, Cinzia; Hehn, Alain; Moglia, Andrea; Menin, Barbara; Bourgaud, Frédéric; Lanteri, Sergio; Portis, Ezio

2009-01-01

Background The leaves of globe artichoke and cultivated cardoon (Cynara cardunculus L.) have significant pharmaceutical properties, which mainly result from their high content of polyphenolic compounds such as monocaffeoylquinic and dicaffeoylquinic acid (DCQ), and a range of flavonoid compounds. Results Hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase (HQT) encoding genes have been isolated from both globe artichoke and cultivated cardoon (GenBank accessions DQ915589 and DQ915590, respectively) using CODEHOP and PCR-RACE. A phylogenetic analysis revealed that their sequences belong to one of the major acyltransferase groups (anthranilate N-hydroxycinnamoyl/benzoyltransferase). The heterologous expression of globe artichoke HQT in E. coli showed that this enzyme can catalyze the esterification of quinic acid with caffeoyl-CoA or p-coumaroyl-CoA to generate, respectively, chlorogenic acid (CGA) and p-coumaroyl quinate. Real time PCR experiments demonstrated an increase in the expression level of HQT in UV-C treated leaves, and established a correlation between the synthesis of phenolic acids and protection against damage due to abiotic stress. The HQT gene, together with a gene encoding hydroxycinnamoyl-CoA:shikimate/quinate hydroxycinnamoyltransferase (HCT) previously isolated from globe artichoke, have been incorporated within the developing globe artichoke linkage maps. Conclusion A novel acyltransferase involved in the biosynthesis of CGA in globe artichoke has been isolated, characterized and mapped. This is a good basis for our effort to understand the genetic basis of phenylpropanoid (PP) biosynthesis in C. cardunculus. PMID:19292932

Winter scene of the Globe of Science and Innovation

CERN Multimedia

patrice loiez

2005-01-01

CERN's Globe exhibition centre is shown on a Swiss winter day. This wooden building was given to CERN in 2004 as a gift from the Swiss Confederation to mark 50 years since the Organization's foundation.

MRI evaluation for conservative treatment in endometriosis and uterine myoma

Energy Technology Data Exchange (ETDEWEB)

Kasai, Mayumi; Karibe, Akihiko; Sato, Ken; Suzuki, Hirosi; Iida, Hajime [Iwate Prefectural Central Hospital, Morioka (Japan); Yamaya, Rie

1991-07-01

Eighteen patients with endometriosis or uterine myoma underwent MRI before and after conservative treatment with Danazol (400 mg/day) or Buserelin (900 {mu}g/day) to examine pathological changes. Of 8 patients with endometrial chocolate cyst, 7 patients were given Dazazol for 3 to 7 months, in whom high signal intensity indicative of mass tended to decrease after chemotherapy especially on T2-weighted images. In addition, the area of cyst was reduced by 31% to 100%. In the remaining one patient receiving Buserelin for 8 months, the reduction rate of cyst was 31%. Ten patients with adenomyosis were classified into the group given Danazol for 5 to 15 months (n=4) and the group given Buserelin for 3 to 8 months (n=6). Low intensity area was decreased by 9% to 25% in the Danazol group and by 20% to 69% in the Buserelin group. Uterine area was reduced by 10% to 32% in the Danazol group and by 4.5% to 51% in the Buserelin group. MRI was helpful in the management of these diseases during conservative treatment. (N.K.).

MRI evaluation for conservative treatment in endometriosis and uterine myoma

International Nuclear Information System (INIS)

Kasai, Mayumi; Karibe, Akihiko; Sato, Ken; Suzuki, Hirosi; Iida, Hajime; Yamaya, Rie.

1991-01-01

Eighteen patients with endometriosis or uterine myoma underwent MRI before and after conservative treatment with Danazol (400 mg/day) or Buserelin (900 μg/day to examine pathological changes. Of 8 patients with endometrial chocolate cyst, 7 patients were given Dazazol for 3 to 7 months, in whom high signal intensity indicative of mass tended to decrease after chemotherapy especially on T2-weighted images. In addition, the area of cyst was reduced by 31% to 100%. In the remaining one patient receiving Buserelin for 8 months, the reduction rate of cyst was 31%. Ten patients with adenomyosis were classified into the group given Danazol for 5 to 15 months (n=4) and the group given Buserelin for 3 to 8 months (n=6). Low intensity area was decreased by 9% to 25% in the Danazol group and by 20% to 69% in the Buserelin group. Uterine area was reduced by 10% to 32% in the Danazol group and by 4.5% to 51% in the Buserelin group. MRI was helpful in the management of these diseases during conservative treatment. (N.K.)

Research Progress of Global Land Domain Service Computing:Take GlobeLand 30 as an Example

Directory of Open Access Journals (Sweden)

CHEN Jun

2017-10-01

Full Text Available Combining service-computing technology with domain requirements is one of the important development directions of geographic information under Internet+, which provides highly efficient technical means for information sharing and collaborative services. Using GlobeLand 30 as an example, this paper analyzes the basic problems of integrating land cover information processing and service computing, introduces the latest research progress in domain service modeling, online computing method and dynamic service technology, and the GlobeLand 30 information service platform. The paper also discusses the further development directions of GlobeLand 30 domain service computing.

What's a Nice Hummingbird Like You Doing at an AGU Meeting Like This? (or, Operation RubyThroat Meets The GLOBE Program)

Science.gov (United States)

Hilton, B.

2003-12-01

the hummingbird protocols and to submit Operation RubyThroat data to GLOBE. Participants report sightings of any RTHUs that are banded and color-marked with dye or that have unusual plumage (albinistic, leucistic, etc.). Participants in the eastern U.S. and Canada also report the occurrence of "winter vagrant" hummingbirds, i.e., species from the western U. S. and Mexico that from August through March seem to be wandering more frequently into the region. These unusual movements by western hummingbird species, as well as migration timing and winter occurrences of RTHUs, are correlated against GLOBE data to determine possible effects of atmosphere, climate, and land use, including the impact of global warming. As a new GLOBE protocol, Operation RubyThroat is just beginning to generate data for analysis. Operation RubyThroat's collaboration with GLOBE is funded by a grant from the National Science Foundation. Support for other aspects of the project comes from, among others, Agilent Technologies, ConocoPhillips (through National Fish and Wildlife Foundation), The Christensen Fund, and individual donors. Operation RubyThroat is an education, research, and conservation initiative of Hilton Pond Center for Piedmont Natural History (www.hiltonpond.org) in York, South Carolina USA.

A VIRTUAL GLOBE-BASED MULTI-RESOLUTION TIN SURFACE MODELING AND VISUALIZETION METHOD

Directory of Open Access Journals (Sweden)

X. Zheng

2016-06-01

Full Text Available The integration and visualization of geospatial data on a virtual globe play an significant role in understanding and analysis of the Earth surface processes. However, the current virtual globes always sacrifice the accuracy to ensure the efficiency for global data processing and visualization, which devalue their functionality for scientific applications. In this article, we propose a high-accuracy multi-resolution TIN pyramid construction and visualization method for virtual globe. Firstly, we introduce the cartographic principles to formulize the level of detail (LOD generation so that the TIN model in each layer is controlled with a data quality standard. A maximum z-tolerance algorithm is then used to iteratively construct the multi-resolution TIN pyramid. Moreover, the extracted landscape features are incorporated into each-layer TIN, thus preserving the topological structure of terrain surface at different levels. In the proposed framework, a virtual node (VN-based approach is developed to seamlessly partition and discretize each triangulation layer into tiles, which can be organized and stored with a global quad-tree index. Finally, the real time out-of-core spherical terrain rendering is realized on a virtual globe system VirtualWorld1.0. The experimental results showed that the proposed method can achieve an high-fidelity terrain representation, while produce a high quality underlying data that satisfies the demand for scientific analysis.

OceanGLOBE: an Outdoor Research and Environmental Education Program for K-12 Students

Science.gov (United States)

Perry, R. B.; Hamner, W. M.

2006-12-01

OceanGLOBE is an outdoor environmental research and education program for upper elementary, middle and high school students, supplemented by online instructional materials that are available without charge to any educator. OceanGLOBE was piloted in 1995 with support from a National Science Foundation Teacher Enhancement project, "Leadership in Marine Science" (award no.ESI-9454413 to UCLA). Continuing support by a second NSF Teacher Enhancement project (award no. ESI-9819424 to UCLA) and by COSEE-West (NSF awards OCE-215506 to UCLA and OCE-0215497 to USC) has enabled OceanGLOBE to expand to a growing number of schools and to provide an increasingly robust collection of marine science instructional materials on its website, http://www.msc.ucla.edu/oceanglobe/ OceanGLOBE provides a mechanism for students to conduct inquiry-based, hands-on marine science research, providing experiences that anchor the national and state science content standards learned in the classroom. Students regularly collect environmental and biological data from a beach site over an extended period of time. In the classroom they organize, graph and analyze their data, which can lead to a variety of student-created science products. Beach research is supported by instructional marine science materials on the OceanGLOBE website. These online materials also can be used in the classroom independent of the field component. Annotated PowerPoint slide shows explain research protocols and provide marine science content. Field guides and photographs of marine organisms (with emphasis on the Southern California Bight) and a growing collection of classroom investigations (applicable to any ocean location) support the science content presented in the beach research program and slide shows. In summary, OceanGLOBE is a comprehensive learning package grounded in hands-on, outdoor marine science research project in which students are the principal investigators. By doing scientific work repetitively over an

Outcomes of conservative treatment for cervical myelopathy caused by soft disc herniation

International Nuclear Information System (INIS)

Matsumoto, Morio; Chiba, Kazuhiro; Ishii, Ken; Ogawa, Yuto; Takaishi, Hironari; Nakamura, Masaya; Toyama, Yoshiaki

2006-01-01

The purposes of this study are to delineate the clinical course and MRI findings of patients with disc hernias which regressed spontaneously and to determine who is eligible for conservative treatment. Twenty-three patients with mild cervical myelopathy (initial Japanese Orthopedic Association (JOA) scores >10) caused by soft disc herniation were treated conservatively for more than two years (13 males, 10 females, mean age 50, mean follow-up 3.6 years). The investigated items included JOA scores and MRI findings (morphology of disc herniation). Morphology of disc herniation was classified into focal type (herniated mass persisting at the intervertebral level) and diffuse type (herniated mass migrating rostrally or caudally) in the sagittal plane and median type or paramedian type in the axial plane. The mean JOA scores were 13.4±1.5 before treatment, and 16.0±1.0 at follow-up. Regression of herniation was observed in 14 patients (Group A), while no regression was seen in 9 patients (Group B). The JOA scores were 13.7±1.5 (Group A) and 14.0±1.6 (Group B) before treatment, and 16.3±1.6 and 15.7±1.2 at follow-up, respectively. On sagittal MR images, diffuse-type herniation was observed in 9 patients (64%) and focal-type in 5 (36%) in Group A, and 3 (33%) and 6 (67%) in Group B, respectively. On axial images, median-type herniation was observed in 10 patients (71%), and paramedian-type in 4 (29%) in Group A, and 6 (67%) and 3 (33%) in Group B, respectively. Spontaneous soft disc regression in patients with cervical myelopathy was observed in more than half of those treated conservatively for longer than 2 years. Conservative treatment can be recommended for patients with mild cervical myelopathy, especially when caused by median-and/or diffuse-type disc hernia, although close observation is mandatory. (author)

Effects of alternative cropping systems on globe artichoke qualitative traits.

Science.gov (United States)

Spanu, Emanuela; Deligios, Paola A; Azara, Emanuela; Delogu, Giovanna; Ledda, Luigi

2018-02-01

Traditionally, globe artichoke cultivation in the Mediterranean basin is based on monoculture and on use of high amounts of nitrogen fertiliser. This raises issues regarding its compatibility with sustainable agriculture. We studied the effect of one typical conventional (CONV) and two alternative cropping systems [globe artichoke in sequence with French bean (NCV1), or in biannual rotation (NCV2) with cauliflower and with a leguminous cover crop in inter-row spaces] on yield, polyphenol and mineral content of globe artichoke heads over two consecutive growing seasons. NCV2 showed statistical differences in terms of fresh product yield with respect to the monoculture systems. In addition, the dihydroxycinnamic acids and dicaffeoylquinic acids of non-conventional samples were one-fold significantly higher than the conventional one. All the samples reported good mineral content, although NCV2 achieved a higher Fe content than conventional throughout the two seasons. After two and three dates of sampling, the CONV samples showed the highest levels of K content. In our study, an acceptable commercial yield and quality of 'Spinoso sardo' were achieved by shifting the common conventional agronomic management to more sustainable ones, by means of an accurate choice of cover crop species and rotations introduced in the systems. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Microbial cultures in open globe injuries in southern India.

Science.gov (United States)

Gupta, Arvind; Srinivasan, Renuka; Kaliaperumal, Subashini; Setia, Sajita

2007-07-01

To determine the risk factors leading to positive intraocular culture in patients with open globe injury. A prospective interventional study involving 110 eyes of 110 patients of more than 15 years of age, presenting with open globe injury, was undertaken. Emergency repair of the injured globe was done. Prolapsed intraocular tissue or aqueous humour was sent for microbial work up before repair. In endophthalmitis cases intravitreal antibiotics were given according to the antimicrobial sensitivity. Chi-square and logistic regression analysis were used to determine the risk factors. Fifty-six patients showed microbial contamination. Bacteria were cultured in 42 patients and fungi in 14 patients. Nineteen patients developed endophthalmitis, of which 18 patients showed microbial growth initially. In univariate analysis, initial visual acuity (8 mm, P 72 h, P 8 mm, P = 0.013) were associated with increased risk of positive microbial culture. Six patients had intraocular foreign body but were culture negative. Age, gender, site of injury and presence of cataract did not significantly affect the culture positivity. Microbial contamination is a risk factor for the development for endophthalmitis. Despite the high frequency of microbial contamination, it develops only in few cases. Systemic antibiotics, virulence of the organism and host factors play a role in the manifestation of endophthalmitis. Prophylaxis with intraocular antibiotics should be strongly considered in cases with poor vision at presentation, larger corneoscleral laceration, delayed surgical intervention and uveal tissue or vitreous prolapse.

Percutaneous Vertebroplasty Versus Conservative Treatment and Rehabilitation in Women with Vertebral Fractures due to Osteoporosis: A Prospective Comparative Study.

Science.gov (United States)

Macías-Hernández, Salvador Israel; Chávez-Arias, Daniel David; Miranda-Duarte, Antonio; Coronado-Zarco, Roberto; Diez-García, María Pilar

2015-01-01

Percutaneous vertebroplasty is commonly used in the management of osteoporosis-related vertebral fractures, although there is controversy on its superiority over conservative treatment. Here we compare pain and function in women with vertebral osteoporotic fractures who underwent percutaneous vertebroplasty versus conservative treatment with a protocolized rehabilitation program. A longitudinal and comparative prospective study was conducted. Women ≥ 60 years of age with a diagnosis of osteoporosis who had at least one vertebral thoracic or lumbar compression fracture were included and divided into two groups, conservative treatment or vertebroplasty. The Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) were used to assess pain and function, respectively, as the outcome measures. We included 31 patients, 13 (42%) treated with percutaneous vertebroplasty and 18 (58%) with conservative treatment. Baseline clinical characteristics, bone densitometry and fracture data were similar in both groups. At baseline, VAS was 73.1 ± 28.36 in the vertebroplasty group and 68.6 ± 36.1 mm in the conservative treatment group (p = 0.632); at three months it was 33.11 ± 10.1 vs. 42 ± 22.21 mm (p = 0.111); and at 12 months, 32.3 ± 11.21 vs. 36.1 ± 12.36 mm (p = 0.821). The ODI at baseline was 83% in the vertebroplasty group vs. 85% for conservative management (p = 0.34); at three months, 36 vs. 39% (p = 0.36); and at 12 months, 29.38 vs. 28.33% (p = 0.66). Treatment with percutaneous vertebroplasty had no advantages over conservative treatment for pain and function in this group of women ≥ 60 years of age with osteoporosis.

Visualizing dynamic geosciences phenomena using an octree-based view-dependent LOD strategy within virtual globes

Science.gov (United States)

Li, Jing; Wu, Huayi; Yang, Chaowei; Wong, David W.; Xie, Jibo

2011-09-01

Geoscientists build dynamic models to simulate various natural phenomena for a better understanding of our planet. Interactive visualizations of these geoscience models and their outputs through virtual globes on the Internet can help the public understand the dynamic phenomena related to the Earth more intuitively. However, challenges arise when the volume of four-dimensional data (4D), 3D in space plus time, is huge for rendering. Datasets loaded from geographically distributed data servers require synchronization between ingesting and rendering data. Also the visualization capability of display clients varies significantly in such an online visualization environment; some may not have high-end graphic cards. To enhance the efficiency of visualizing dynamic volumetric data in virtual globes, this paper proposes a systematic framework, in which an octree-based multiresolution data structure is implemented to organize time series 3D geospatial data to be used in virtual globe environments. This framework includes a view-dependent continuous level of detail (LOD) strategy formulated as a synchronized part of the virtual globe rendering process. Through the octree-based data retrieval process, the LOD strategy enables the rendering of the 4D simulation at a consistent and acceptable frame rate. To demonstrate the capabilities of this framework, data of a simulated dust storm event are rendered in World Wind, an open source virtual globe. The rendering performances with and without the octree-based LOD strategy are compared. The experimental results show that using the proposed data structure and processing strategy significantly enhances the visualization performance when rendering dynamic geospatial phenomena in virtual globes.

A study on the impact of the GLOBE program on students' attitudes regarding environmental issues

Science.gov (United States)

Manfready, Gary Martin

A key objective in environmental curricula should be to instill responsible and concerned attitudes toward environmental issues. This can be accomplished through the application of innovative programs which emphasize the development of the affective domain of learning. The development of personal attitudes is one form of evidence that the affective domain is being addressed. This study was undertaken to determine the impact of the GLOBE program (Global Learning and Observation to Benefit the Environment) on the attitudes of students toward environmental issues. Three hundred and five middle and high school level students from four states were surveyed to determine their attitudes toward selected environmental statements. Results demonstrated that attitudes toward environmental issues of GLOBE students were significantly greater than non-GLOBE students. Additional analysis demonstrated that regardless of grade levels, gender, racial and ethnicity backgrounds, depth of GLOBE involvement, and degree of teachers' GLOBE experiences, GLOBE students display similar levels of attitudes toward environmental issues. Establishment of a reliable Likert scale measurement instrument was accomplished. Permission to use an existing survey was obtained. Additional items were added to increase validity. Establishment of reliability was accomplished through a Guttman split half analysis of the piloted instrument. Through the use of factor analysis, four categories or sub-groupings of attitudes were determined to exist. Reliability was established for the factors. These sub-groupings were identified as personal commitment to environmental protection, awareness of avenues for action, loci of control, and students' perception of teachers' abilities to present environmental topics. These categories were a part of the analysis of four hypotheses.

Assessing the accuracy of globe thermometer method in predicting outdoor mean radiant temperature under Malaysia tropical microclimate

Science.gov (United States)

Khrit, N. G.; Alghoul, M. A.; Sopian, K.; Lahimer, A. A.; Elayeb, O. K.

2017-11-01

Assessing outdoor human thermal comfort and urban climate quality require experimental investigation of microclimatic conditions and their variations in open urban spaces. For this, it is essential to provide quantitative information on air temperature, humidity, wind velocity and mean radiant temperature. These parameters can be quantified directly except mean radiant temperature (Tmrt). The most accurate method to quantify Tmrt is integral radiation measurements (3-D shortwave and long-wave) which require using expensive radiometer instruments. To overcome this limitation the well-known globe thermometer method was suggested to calculate Tmrt. The aim of this study was to assess the possibility of using indoor globe thermometer method in predicting outdoor mean radiant temperature under Malaysia tropical microclimate. Globe thermometer method using small and large sizes of black-painted copper globes (50mm, 150mm) were used to estimate Tmrt and compare it with the reference Tmrt estimated by integral radiation method. The results revealed that the globe thermometer method considerably overestimated Tmrt during the middle of the day and slightly underestimated it in the morning and late evening. The difference between the two methods was obvious when the amount of incoming solar radiation was high. The results also showed that the effect of globe size on the estimated Tmrt is mostly small. Though, the estimated Tmrt by the small globe showed a relatively large amount of scattering caused by rapid changes in radiation and wind speed.

Conservative treatment for invasive lobular carcinoma of the breast

International Nuclear Information System (INIS)

Dilhuydy, Jean-Marie; Salem, Naji; Durand, Michel; Prie, Loiec; Stoeckle, Eberhard; Benyoucef, Ahmed; Dilhuydy, Marie-Helene

1997-01-01

Purpose/Objective: To evaluate the place of conservative treatment in invasive lobular carcinoma. Materials and Methods: From 01/01/85 to 31/12/92, 109 patients with clinically and mammographically unifocal invasive lobular carcinoma of the breast (T<35 mm) underwent tumorectomy, axillary dissection and radiation therapy; they received an adjuvant treatment in case of nodal involvement (n = 31) or lack of estrogen and progesterone receptors (n = 16). The entire breast received 50 Gy with a systematic boost of 10 Gy. Results: With a median follow-up of 86 months, we observed 11 isolated local recurrences (T0 = (3(19)), T1 = (6(41)), T2 = (2(49))), 7 local recurrences associated with metastases (T1 = (3(41)), T2 = (4(49))) and 7 cases of metastatic diseases (T1 = (4(41)), T2 = (3(49))). Among the 11 patients with isolated local recurrence, 7 are alive with no evidence of disease after salvage mastectomy. Nine contro-lateral breast cancers occurred, 2 synchronous and 7 metachronous. The 5-year actuarial local relapse free survival, metastase free survival and overall survival are respectively 87.3%, 89.5% and 92.5%, whatever histological subtypes. These results are comparable to those obtained in 1393 cases of infiltrating ductal carcinoma similarly treated during the same period in our institute, except for local relapse (87.3% vs 91%, p = 0.008). Conclusion: Conservative treatment for invasive lobular carcinoma of the breast (T<35 mm) is appropriate in the absence of clinical or mammographic multifocality

FEASIBILITY OF THE CONSERVATIVE TREATMENT OF SPLENIC INJURIES IN BLUNT ABDOMINAL TRAUMA

Directory of Open Access Journals (Sweden)

M. M. Abakumov

2013-01-01

Full Text Available ABSTRACT. In blunt trauma, the structural features of the splenic parenchyma usually predispose to a significant intra-abdominal bleeding, so the excision of the damaged spleen is considered a main treatment technique in a majority of cases. However, a number of recent clinical studies have proved the necessity of a differentiated approach to making the treatment decisions and demonstrated the possibility of spleen salvage in certain cases.The most debatable issue is the management tactics in splenic injury associated with the formation of subcapsular hematoma. It is necessary to emphasize that the conservative treatment of such splenic injury implies a persisting risk of double-stage splenic rupture with following intra-abdominal bleeding.The Sklifosovsky Research Institute traditionally deals with injury management in all aspects and has gained a wide experience in splenic injury treatment that makes possible to demonstrate the choice of treatment tactics with regard to the splenic injury severity, and patient’s condition. A conservative management of spleen injury is reasonable only in stable patients and requires an additional use of instrumental diagnostic techniques. Morphological studies suggest that reparation processes around the splenic hematoma arise early enough and proceed, as a rule, with no signs of a purulent inflammation. 

Conservative Treatment Protocol for Keratocystic Odontogenic Tumour: a Follow-up Study of 3 Cases

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Gülsün Yildirim

2010-07-01

Full Text Available Background: The keratocystic odontogenic tumour is classified as a developmental cyst derived from the enamel organ or from the dental lamina. The treatment of keratocystic odontogenic tumour of the jaw remains controversial. The aim of this study was to report the outcome of our conservative treatment protocol for keratocystic odontogenic tumour.Methods: Three patients with different complaints referred to Oral and Maxillofacial Surgery Clinic, Faculty of Dentistry, Selçuk University. Initial biopsy was carried out in all patients and keratocystic odontogenic tumours was diagnosed subsequent to histopathological examination. The patients with keratocystic odontogenic tumours were treated by enucleation followed by open packing. This conservative treatment protocol was selected because of existing young aged patients. The average follow-up duration of the cases was 2 years.Results: Out of 3 cases, 2 lesions were present in mandible and 1 lesion in maxilla. There was no evidence of recurrence during follow-up. All the cases were monitored continuously with panoramic radiographs, computed tomography and clinical evaluations.Conclusions: This conservative treatment protocol for keratocystic odontogenic tumours, based on enucleation followed by open packing would be a possible choice with a view of offering low recurrence rate and low morbidity rate particularly in young patients.

The Significance of Ongoing Teacher Support in Earth Science Education Programs: Evidence from the GLOBE Program

Science.gov (United States)

Penuel, B.; Korbak, C.; Shear, L.

2003-12-01

The GLOBE program provides a rich context for examining issues concerning implementation of inquiry-oriented, scientist-driven educational programs, because the program has both a history of collecting evaluation data on implementation and mechanisms for capturing program activity as it occurs. In this paper, researchers from SRI International's evaluation team explore the different roles that regional partners play in preparing and supporting teachers to implement the GLOBE Program, an international inquiry-based Earth science education initiative that has trained over 14,000 teachers worldwide. GLOBE program evaluation results show the program can be effective in increasing students' inquiry skills, but that the program is also hard for teachers to implement (Means et al., 2001; Penuel et al., 2002). An analysis of GLOBE's regional partner organizations, which are tasked with preparing teachers to implement its data collection and reporting protocols with students, shows that some partners are more successful than others. This paper reports findings from a quantitative analysis of the relationship between data reporting and partner support activities and from case studies of two such regional partners focused on analyzing what makes them successful. The first analysis examined associations between partner training and support activities and data reporting. For this analysis, we used data from the GLOBE Student Data Archive matched with survey data collected from a large sample of GLOBE teachers as part of SRI's Year 5 evaluation of GLOBE. Our analyses point to the central importance of mentoring and material support to teachers. We found that incentives, mentoring, and other on-site support to teachers have a statistically significant association with higher data reporting levels. We also found that at present, teachers access these supports less often than they access listservs and e-mail communication with teachers after GLOBE training. As a follow-up to this

Salvage treatment for local or local-regional recurrence after initial breast conservation treatment with radiation for ductal carcinoma in situ

NARCIS (Netherlands)

Solin, Lawrence J.; Fourquet, Alain; Vicini, Frank A.; Taylor, Marie; Haffty, Bruce; Strom, Eric A.; Wai, Elaine; Pierce, Lori J.; Marks, Lawrence B.; Bartelink, Harry; Campana, Francois; McNeese, Marsha D.; Jhingran, Anuja; Olivotto, Ivo A.; Bijker, Nina; Hwang, Wei-Ting

2005-01-01

The present study evaluated the outcome of salvage treatment for women with local or local-regional recurrence after initial breast conservation treatment with radiation for mammographically detected ductal carcinoma in situ (DCIS; intraductal carcinoma) of the breast. The study cohort consisted of

Exeresis and Brachytherapy as Salvage Treatment for Local Recurrence After Conservative Treatment for Breast Cancer: Results of a Ten-Year Pilot Study

International Nuclear Information System (INIS)

Guix, Benjamin; Lejarcegui, Jose Antonio; Tello, Jose Ignacio; Zanon, Gabriel; Henriquez, Ivan; Finestres, Fernando; Martinez, Antonio; Fernandez-Ibiza, Jaume; Quinzanos, Luis; Palombo, Pau; Encinas, Xavier; Guix, Ines

2010-01-01

Purpose: To analyze the long-term results of a pilot study assessing excision and brachytherapy as salvage treatment for local recurrence after conservative treatment of breast cancer. Methods and Materials: Between December 1990 and March 2001, 36 patients with breast-only recurrence less than 3 cm in diameter after conservative treatment for Stage I or II breast carcinoma were treated with local excision followed by high-dose rate brachytherapy implants (30 Gy in 12 fractions over a period of 5 days). No patient was lost to follow-up. Special attention was paid to local, regional, or distant recurrences; survival; cosmesis; and early and late side effects. Results: All patients completed treatment. During follow-up (range, 1-13 years), 8 patients presented metastases (2 regional and 6 distant) as their first site of failure, 1 had a differed local recurrence, and 1 died of the disease. Actuarial results at 10 years were as follows: local control, 89.4%; disease-free survival, 64.4%; and survival, 96.7%. Cosmetic results were satisfactory in 90.4%. No patient had Grade 3 or 4 early or late complications. Of the 11 patients followed up for at least 10 years, all but 1 still had their breast in place at the 10-year stage. Conclusions: High-dose rate brachytherapy is a safe, effective treatment for small-size, low-risk local recurrence after local excision in conservatively treated patients. The dose of 30 Gy of high-dose rate brachytherapy (12 fractions over a period of 5 days twice daily) was well tolerated. The excellent results support the use of breast preservation as salvage treatment in selected patients with local recurrence after conservative treatment for breast cancer.

Patients’ perceptions of conservative treatment for a small abdominal aortic aneurysm

Directory of Open Access Journals (Sweden)

Tomee SM

2018-01-01

Full Text Available Stephanie M Tomee,1 Winifred A Gebhardt,2 Jean-Paul PM de Vries,3 Victoria C Hamelinck,1 Jaap F Hamming,1 Jan HN Lindeman1 1Department of Surgery, Leiden University Medical Center, Leiden, 2Health, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, Leiden, 3Department of Vascular Surgery, St Antonius Hospital, Nieuwegein, Leiden, the Netherlands Background: An abdominal aortic aneurysm (AAA is a progressive, generally symptomless disease that could ultimately result in a fatal rupture. Current guidelines advise conservative follow-up, and preventive surgical repair once the risk of rupture outweighs the cost of repair (55 mm in men. In developed countries, the majority of patients are diagnosed with AAAs less than 55 mm, and so enter a period of conservative surveillance. An important question is how patients perceive and cope with risk of rupture, AAA diagnosis and treatment, and presented AAA information. The goal of this study was to gain insight into patients’ perceptions of conservative treatment for a small AAA to increase patient satisfaction.Methods: We conducted semistructured in-depth interviews and used questionnaires measuring health-related quality of life (RAND 36-Item Health Survey 1.0, illness-perceptions (Illness Perception Questionnaire – Revised, and anxiety and depression (Hospital Anxiety and Depression Scale. Interviews were audio recorded and transcript contents were analyzed based on grounded theory. Mean scores of the questionnaires were compared to (population reference groups.Results: This study included ten male patients under surveillance for a small AAA from two hospitals in the Netherlands. Patients expressed no fear for AAA rupture, and also reported low levels of anxiety and depression in both the interviews and the Hospital Anxiety and Depression Scale. The presence of an AAA did not affect their social life or emotional well-being. The reported poorer physical health on RAND 36

“Universe of Particles” opens in the Globe

CERN Multimedia

Carolyn Lee

2010-01-01

CERN’s brand new permanent exhibition provides a high-tech experience with virtual interactive stations and pieces of actual detectors to intrigue the general public about some of the world’s most sophisticated physics tools and experiments.   Universe of Particles exhibition will open on 1 July in the Globe of Science and Technology. Upon entering the dark interior of the Globe, one has a sense of emerging into a portal to the outer universe. Large projections that fill the walls and a 6 m large diameter circle screen in the middle of the ground where space swirls with stars and planets, as well as particle collisions from the LHC experiments. Questions such as where do we come from? What are the laws of Nature? Why did antimatter and matter not destroy each other just after the Big Bang? Will we find particles that make up the mysterious dark matter or the Higgs particle? are linked to the research being done at the LHC. Visitors are invited to explore the unique spherica...

CinéGlobe presents: "One Day on Earth"

CERN Multimedia

2012-01-01

The CinéGlobe International Film Festival is proud to announce that it will be hosting the Swiss edition of the Global Screening of “One Day on Earth”, the first film to be shot and then screened in every country in the world.   Founded in 2008, “One Day on Earth's” first media creation event occurred on 10.10.10. The collaboration was the first ever simultaneous filming event occuring in every country of the world. It created a unique geo-tagged video archive as well as a unique feature film. “One Day on Earth” showcases the amazing diversity, conflict, tragedy, and triumph that occurs in one day on our planet.  This Earth Day, April 22nd, CinéGlobe and CERN invite the public to a free global screening event of the first One Day on Earth Motion Picture. This unique film, created from over 3000 hours of footage, was shot by the One Day on Earth community in every country of the world on October...

Conservative treatment of lumbar spondylolysis in young soccer players.

Science.gov (United States)

Alvarez-Díaz, Pedro; Alentorn-Geli, Eduard; Steinbacher, Gilbert; Rius, Marta; Pellisé, Ferran; Cugat, Ramón

2011-12-01

The purpose of this study was to report the functional outcomes of young active soccer players with lumbar spondylolysis undergoing conservative treatment. Between 2002 and 2004, all soccer players diagnosed with spondylolysis with a minimum 2-year follow-up were retrospectively reviewed. All patients were treated nonoperatively with cessation of sports activity and rehabilitation for 3 months. The rehabilitation protocol was identical for all patients and emphasized strengthening of abdominal muscles, stretching of the hamstrings, "core" stability exercises, and trunk rotational movements in a pain-free basis. Those patients with pain at rest and with daily life activities were also treated with a thoracolumbar orthosis. Symptomatic patients or those with positive SPECT were not allowed to return to sports and continued the rehabilitation protocol for 3 more months. The mean time of cessation of sports activity was 3.9 months (SD 0.8) and 5.2 months (SD 2.1) for a complete return to sports. At the 2-year follow-up, 28 patients (82%) obtained excellent results, 4 (12%) good results, 1 patient (3%) a fair result, and 1 patient (3%) a poor result. Conservative treatment of spondylolysis in young soccer players with cessation of sports and rehabilitation, with or without thoracolumbar orthosis, was associated with excellent functional results in terms of return to sports and level of achievable physical activity.

A 3D Planetary Neocartographic Tool in Education: A Game on Virtual Moon and Mars Globes

Science.gov (United States)

Hargitai, H.; Simonné-Dombóvári, E.; Gede, M.

2012-03-01

The paper describes the educational use of online virtual globes of Mars and the Moon. The game uses topographic globes of Mars (MOLA) and the Moon (LRO DTM) that includes IAU nomenclature + informal names. Students have to position the points described.

The Multidisciplinary Conservative Approach in Treatment of TOS

Directory of Open Access Journals (Sweden)

F. Layeghi

2010-10-01

Full Text Available Objectives: The aims of this study were to evaluate the efficacy of conservative treatment in patients with and without cervical ribs and Thoracic Outlet Syndrome (TOS. From so many kinds of conservative treatment in literature, we used a multidisciplinary approach (correction of posture, maximizing muscle endurance and power, stretch shorten muscles, massage for trigger points and maximize thoracic span with stomach breathing to get more effective treatment and a longer time of relief with less duration and more long-term relief. Methods: Twenty six female patients with or without cervical ribs, pain and numbness were included in this study. They were assessed in terms of posture, muscle testing and shortness in muscles in all part of the body. Initial pain status were recorded and after eight weeks treatment including posture correction, their pain were assessed again with visual analogue scale that 0 was no pain and 10 was intolerable pain. Results: In 100 % of patients initial pain score were more than 5 in visual analogue scale. 23.1% of cases showed reduced pain scores to lower than 5 scales. Age was not a significant factor (P=0.93 on pain reducing. Type of posture was independent from pain and pain diminishing (0.004. Cervical rib was effective in initial pain (P=0.08 and degree of diminishing pain (P=0.236. Initial pain of 57.1% of patients with cervical rib was 10 due to visual analogue scale (VAS. In 33.3% of the persons with bilateral cervical rib we saw more than 5 degree in diminishing pain. In the 85.7% patients with unilateral cervical rib, we had more than 5 degree diminishing pain and we saw this in all of the non cervical rib TOS. Dicussion: Faulty posture can cause narrowing of the thoracic outlet space and may lead to pain and numbness, and some other symptoms. Correction of posture despite of cervical rib can widen the space and reduces pressure on vessels and nerves. Postural correction and long time follow up must be

Data Basin Aquatic Center: expanding access to aquatic conservation data, analysis tools, people and practical answers

Science.gov (United States)

Osborne-Gowey, J.; Strittholt, J.; Bergquist, J.; Ward, B. C.; Sheehan, T.; Comendant, T.; Bachelet, D. M.

2009-12-01

The world’s aquatic resources are experiencing anthropogenic pressures on an unprecedented scale and aquatic organisms are experiencing widespread population changes and ecosystem-scale habitat alterations. Climate change is likely to exacerbate these threats, in some cases reducing the range of native North American fishes by 20-100% (depending on the location of the population and the model assumptions). Scientists around the globe are generating large volumes of data that vary in quality, format, supporting documentation, and accessibility. Moreover, diverse models are being run at various temporal and spatial scales as scientists attempt to understand previous (and project future) human impacts to aquatic species and their habitats. Conservation scientists often struggle to synthesize this wealth of information for developing practical on-the-ground management strategies. As a result, the best available science is often not utilized in the decision-making and adaptive management processes. As aquatic conservation problems around the globe become more serious and the demand to solve them grows more urgent, scientists and land-use managers need a new way to bring strategic, science-based, and action-oriented approaches to aquatic conservation. The Conservation Biology Institute (CBI), with partners such as ESRI, is developing an Aquatic Center as part of a dynamic, web-based resource (Data Basin; http: databasin.org) that centralizes usable aquatic datasets and provides analytical tools to visualize, analyze, and communicate findings for practical applications. To illustrate its utility, we present example datasets of varying spatial scales and synthesize multiple studies to arrive at novel solutions to aquatic threats.

Le CERN s'offre un Globe pour séduire le public et les entreprises

CERN Multimedia

Tesnier, Gregory

2004-01-01

The Globe will be open for the public during 2005; a trip that goes from infinitely small to infinitely large will be explained to the visitors at the first floor; exhibitions, conferences and seminars will be also held there and the Globe will be also used for exchanges between CERN and the Industry

The w-categories associated with products of infinite-dimensional globes

International Nuclear Information System (INIS)

Cui, H.

2000-11-01

The results in this thesis are organised in four chapters. Chapter 1 is preliminary. We state the necessary definitions and results in w- complexes, atomic complexes and products of w-complexes. Some definitions are restated to meet the requirement for the following chapters. There is a new proof for the existence of 'natural homomorphism' (Theorem 1.3.6) and a new result for the decomposition of molecules in loop-free w-complexes (Theorem 1.4.13). In Chapter 2, we study the product of three infinite dimensional globes. The main result in this chapter is that a subcomplex in the product of three infinite dimensional globes is a molecule if and only if it is pairwise molecular (Theorem 2.1.6). The definition for pairwise molecular subcomplexes is given in section 1. One direction of the main theorem, molecules are necessarily pairwise molecular, is proved in section 2. Some properties of pairwise molecular subcomplexes are studied in section 3. These properties are the preparation for a more explicit description of pairwise molecular subcomplexes, which is given in section 4. The properties for the sources and targets of pairwise molecular subcomplexes are studied in section 5, where we prove that the class of pairwise molecular subcomplexes is closed under source and target operation; there are also algorithms to calculate the sources and targets of a pairwise molecular subcomplex. Section 6 deals with the composition of pairwise molecular subcomplexes. The proof of the main theorem is completed in section 7, where an algorithm for decomposing molecules into atoms is implied in the proof. The construction of molecules in the product of three infinite dimensional globes is studied in Chapter 3. The main result is that any molecule can be constructed inductively by a systematic approach. Section 1 gives another description for molecules in the product of three infinite dimensional globes which is the theoretical basis for the construction. Section 2 states the

Conservative treatment of intra-articular distal phalanx fractures in horses not used for racing.

Science.gov (United States)

Ohlsson, J; Jansson, N

2005-04-01

To determine the success rate and whether specific patient and treatment factors influenced the outcome after conservative treatment with a bar shoe with quarter clips of intra-articular fractures of the distal phalanx in horses not used for racing. Retrospective study. Thirty-two client-owned horses. Hospital records of horses that had been treated conservatively for intra-articular fractures of the distal phalanx at Skara Equine Hospital or Halland Animal Hospital in Sweden between 1995 and 2001 were reviewed. Racehorses in active training and horses affected with other musculoskeletal diseases were excluded from the study. Follow-up was performed by questionnaire and telephone inquires to the owners 1 to 7 years after injury. Twenty-two horses (69%) returned to their previous or expected level of use and did not wear their bar shoe when they were put back into training. There was no statistically significant correlation between outcome and patient or treatment variables, or bony union of the fracture. Conservative treatment of intra-articular fractures of the distal phalanx carries a fair prognosis for return to previous or expected level of use in horses not used for racing. Radiographic evidence of fracture healing and age of the patient do not seem to influence the prognosis. Horses not used for racing do not need to be shod with a bar shoe with quarter clips for the rest of their athletic career.

Breast carcinoma conservative treatment. Stages I and II

International Nuclear Information System (INIS)

Monti, C.R.

1990-01-01

From 1981 to 1988, 265 patients with breast cancer stages I and II (UICC-1987), were evaluated after conservative treatment with quadrantectomy plus axillectomy, radiotherapy and chemotherapy. After surgical treatment, the patients were submitted to radiation therapy in the breast. One hundred and fifty six (58,8%) patients were submitted to adjuvant chemotherapy. The median clinical follow-up period was 42.8 months with a minimum of 24 and a maximum of 99 months. Six (2,3%) patients presented local recurrence and 48 (18,1%) presented distant metastasis. After five years the total survival rate was 89,7% and the disease free survival rate was 75% in the same period. The study did not show significant differences among the clinical stages classified after surgery and the use of adjuvant chemotherapy did not influence the results of the many stages. (author). 194 refs, 33 figs, 6 tabs

Comparison of classical dermatoscopy and acrylic globe magnifier dermatoscopy

DEFF Research Database (Denmark)

Lorentzen, Henrik F; Eefsen, Rikke Løvendahl; Weismann, Kaare

2008-01-01

Dermatoscopic asymmetry of melanocytic skin lesion is pivotal in most algorithms assessing the probability of melanoma. Larger lesions cannot be assessed by dermatoscopy and the Dermaphot in a single field of vision, but this can be performed using the acrylic globe magnifier. We examined the dia...

The Globe of Science and Innovation's central vortex

CERN Multimedia

Patrice Loiez

2004-01-01

The central vortex of the Globe of Science and Innovation is a crown measuring 6.15 m in diameter and 4.5 m in height. Having been lifted by a crane to a height of over 22 m, the vortex is placed on a support structure which will be removed once the 36 arcs providing the building's structure have been secured in place.

Google Earth: A Virtual Globe for Elementary Geography

Science.gov (United States)

Britt, Judy; LaFontaine, Gus

2009-01-01

Originally called Earth Viewer in 2004, Google Earth was the first virtual globe easily available to the ordinary user of the Internet. Google Earth, at earth.google.com, is a free, 3-dimensional computer model of Earth, but that means more than just a large collection of pretty pictures. It allows the viewer to "fly" anywhere on Earth "to view…

Hyaluronic acid and other conservative treatment options for osteoarthritis of the ankle

NARCIS (Netherlands)

Witteveen, Angelique G. H.; Hofstad, Cheriel J.; Kerkhoffs, Gino M. M. J.

2015-01-01

Background The cause of ankle osteoarthritis (OA) is usually trauma. Patients are relatively young, since ankle trauma occurs at a relatively young age. Several conservative treatment options are available, evidence of the benefits and harms of these options are lacking. Objectives To assess the

Cohort study of lumbar percutaneous chemonucleolysis using ethanol gel in sciatica refractory to conservative treatment.

Science.gov (United States)

Touraine, Sébastien; Damiano, Joël; Tran, Olivia; Laredo, Jean-Denis

2015-11-01

To investigate the efficacy of percutaneous chemonucleolysis using ethanol gel (PCEG) in alleviating radicular pain due to disc herniation after failure of conservative treatment. After failure of conservative treatment, PCEG was performed under fluoroscopic guidance in 42 patients with sciatica >4/10 on a Visual Analog Scale (VAS) for at least 6 weeks and consistent disc herniation on MRI or CT <3 months. The VAS pain score was determined at baseline, then after 1 and 3 months. We assessed the influence of patient-related factors (age, gender, pain duration) and disc herniation-related factors (level, migration pattern, disc herniation-related spinal stenosis) on outcome of PCEG. Mean pain duration was 6.7 months. Pain intensity decreased by 44% and 62.6% after 1 and 3 months, respectively, versus baseline (P = 0.007). A mild improvement was noted by the rheumatologist in 30/42 (71.4%) and 36/42 (85.7%) patients after 1 and 3 months, respectively, and in 31/42 (73.8%) and 33/42 (78.6%) patients by self-evaluation. Patients who failed PCEG were significantly older (49.8 vs. 37.3 years, P = 0.03). None of the other variables studied were significantly associated with pain relief. PCEG may significantly improve disc-related radicular pain refractory to conservative treatment. • Percutaneous chemonucleolysis using ethanol gel (PCEG) is feasible on an outpatient basis. • PCEG improves disc-related radicular pain refractory to conservative treatment. • PCEG is feasible on an outpatient basis. • Failure of PCEG does not interfere with subsequent spinal surgery.

The national survey of breast cancer treatment pattern in Korea (1998): the use of breast-conserving treatment

International Nuclear Information System (INIS)

Shin, Hyun Soo; Chang, Sei Kyung; Lee, Hyung Sik

2004-01-01

In order to improve the proper use of radiotherapy and breast-conserving treatment (BCT) in the management of breast cancer, current status of breast cancer treatment in Korea was surveyed nationwide and the use of BCT were evaluated. Patients characteristics and treatment pattern of 1048 breast cancer patients from 27 institutions diagnosed between January, 1998 and June, 1998 were analyzed. The incidence of receiving BCT was analyzed according to the stage, age, geography, type of hospital, and the availability of radiotherapy facility. Radical mastectomy was performed in 64.8% of total patients and 26% of patients received breast-conserving surgery (BCS). The proportions of patients receiving BCT were 47.5% in stage 0, 54.4% in stage I and 20.3% in stage II. Some of the patients (6.6% of stage I, 10.1% of stage II and 66.7% of stage III) not received radiotherapy after BCS. Only 45% of stage III patients received post-operative radiotherapy after radical mastectomy. The proportion of patients receiving BCT was different according to the geography and availability of radiotherapy facilities. Radiotherapy was not fully used in the management of breast cancer, even in the patients received breast-conserving surgery. The proportion of the patients who received BCT was lower than the report of western countries. To improve the application of proper management of breast cancer, every efforts such as a training of physicians, public education, and improving accessibility of radiotherapy facilities should be done. The factors predicting receipt of BCT were accessibility of radiotherapy facility and geography. Also, periodic survey like current research is warranted

Aerial drone misadventure: A novel case of trauma resulting in ocular globe rupture

Directory of Open Access Journals (Sweden)

Eliza E. Moskowitz

2018-06-01

Full Text Available Purpose: The purpose of this case report is to present the novel findings of a drone causing such a traumatic ocular injury and provide recommendations for how it might be prevented. Observations: We report on a recent case where a child presented to our Emergency Department after incurring a blow to the face by the propeller of a remote controlled drone. The patient suffered significant trauma including rupture of the right globe. Conclusions: As drone sales continue to rise, it is important that physicians be prepared to treat the potential injuries that may result from using these devices. Furthermore, in an attempt to reduce the number of visits associated with remote controlled drones, physicians should be prepared to provide advice as to how patients can reduce the risks of injury. Importance: We hope that the framework and recommendations below will help physicians decrease adverse outcomes related to this unusual injury pattern. Keywords: Drone, Trauma, Globe injury, Globe rupture, Ocular trauma, Corneal trauma, Scleral trauma

GLOBE at Night: Raising Public Awareness and Involvement through Citizen Science

Science.gov (United States)

Walker, C. E.; Pompea, S. M.; Sparks, R. T.

2010-12-01

With half of the world’s population now living in cities, many urban dwellers have never experienced the wonderment of pristinely dark skies and maybe never will. Light pollution is obscuring people’s long-standing natural heritage to view stars. The GLOBE at Night program (www.globeatnight.org) is an international citizen-science campaign to raise public awareness of the impact of light pollution by encouraging everyone everywhere to measure local levels of night sky brightness and contribute observations online to a world map. In the last 5 years, GLOBE at Night has been the most productive public light pollution monitoring campaign, collecting over 52,000 observations in a two-week period annually. This year, during the moonless two weeks in March, the campaign set a record high of over 17,800 measurements from people in 86 countries. Foundational resources are available to facilitate the public’s participation in promoting dark skies awareness. The GLOBE at Night website explains clearly the simple-to-participate-in 5 step program and offers background information and interactive games on key concepts. The program has been expanded to include trainings of the general public, but especially educators in schools, museums and science centers, in unique ways. Education kits for dark skies awareness have been distributed at the training workshops. The kit includes material for a light shielding demonstration, a digital Sky Quality Meter and “Dark Skies Rangers” activities. The activities are on how unshielded light wastes energy, how light pollution affects wildlife and how you can participate in a citizen-science star-hunt like GLOBE at Night. In addition, projects are being developed for what to do with the data once it is taken. The GLOBE at Night data from different years can be compared to look for trends over time or with population density maps. The data can also be used to search for dark sky oases or to monitor lighting ordinance compliance. Most

Tilt, Decentration, and Internal Higher-Order Aberrations of Sutured Posterior-Chamber Intraocular Lenses in Patients with Open Globe Injuries

Directory of Open Access Journals (Sweden)

Xiangjia Zhu

2017-01-01

Full Text Available Purpose. To evaluate the tilt, decentration, and internal higher-order aberrations (HOAs of sutured posterior-chamber intraocular lenses (IOLs in patients with open globe injuries. Methods. 46 consecutive patients (47 eyes who underwent transsclerally sutured IOL implantation were enrolled in this prospective cohort study. Nineteen eyes had a history of open globe injury. The tilt and decentration of the IOLs and the visual quality were measured 1 month after surgery. Results. The horizontal tilt and decentration of the IOLs in the open-globe-injury group were significantly higher than those in the control group (both P<0.05. In the open-globe-injury group, the horizontal decentration was significantly greater in the limbus-sclera-involved group (n=11 than in the only-cornea-involved group (n=8, P=0.040. The internal coma, 3rd-order, and total HOA values at pupil sizes of 4 mm (P=0.006 and 6 mm (P=0.013 were significantly higher in the open-globe-injury group than in the controls. Consequently, the optical quality data for the modulation transfer function and the Strehl ratio (all P<0.05 were significantly poorer in the open-globe-injury group. Conclusions. Open globe injuries damage the structural integrity of the eyeball, resulting in more-misaligned sutured IOLs and poorer visual quality.

An Arduino Based Citizen Science Soil Moisture Sensor in Support of SMAP and GLOBE

Science.gov (United States)

Podest, E.; Das, N. N.; Rajasekaran, E.; Jeyaram, R.; Lohrli, C.; Hovhannesian, H.; Fairbanks, G.

2017-12-01

Citizen science allows individuals anywhere in the world to engage in science by collecting environmental variables. One of the longest running platforms for the collection of in situ variables is the GLOBE program, which is international in scope and encourages students and citizen scientists alike to collect in situ measurements. NASA's Soil Moisture Active Passive (SMAP) satellite mission, which has been acquiring global soil moisture measurements every 3 days of the top 5 cm of the soil since 2015, has partnered with the GLOBE program to engage students from around the world to collect in situ soil moisture and help validate SMAP measurements. The current GLOBE SMAP soil moisture protocol consists in collecting a soil sample, weighing, drying and weighing it again in order to determine the amount of water in the soil. Preparation and soil sample collection can take up to 20 minutes and drying can take up to 3 days. We have hence developed a soil moisture measurement device based on Arduino- microcontrollers along with off-the-shelf and homemade sensors that are accurate, robust, inexpensive and quick and easy to use so that they can be implemented by the GLOBE community and citizen scientists alike. In addition, we have developed a phone app, which interfaces with the Arduino, displays the soil moisture value and send the measurement to the GLOBE database. This talk will discuss building, calibration and validation of the soil moisture measuring device and assessing the quality of the measurements collected. This work was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.

A suggested model for physical examination and conservative treatment of athletic pubalgia.

Science.gov (United States)

Hegedus, Eric J; Stern, Ben; Reiman, Michael P; Tarara, Dan; Wright, Alexis A

2013-02-01

Athletic pubalgia (AP) is a chronic debilitating syndrome that affects many athletes. As a syndrome, AP is difficult to diagnose both with clinical examination and imaging. AP is also a challenge for conservative intervention with randomized controlled trials showing mixed success rates. In other syndromes where clinical diagnosis and conservative treatment have been less than clear, a paradigm has been suggested as a framework for clinical decision making. To propose a new clinical diagnostic and treatment paradigm for the conservative management of AP. Relevant studies were viewed with regard to diagnosis and intervention and where a gap in evidence existed, clinical expertise was used to fill that gap and duly noted. A new paradigm is proposed to assist with clinical diagnosis and non-surgical intervention in patients suffering with AP. The level of evidence supporting this paradigm, according to the SORT taxonomy, is primarily level 2B. Further testing is warranted but following the suggested paradigm should lead to a clearer diagnosis of AP and allow more meaningful research into homogeneous patient populations within the AP diagnostic cluster. Strength-of-Recommendation Taxonomy (SORT): 2B. Copyright © 2012 Elsevier Ltd. All rights reserved.

Direct Analysis in Real Time Mass Spectrometry for the Nondestructive Investigation of Conservation Treatments of Cultural Heritage

Directory of Open Access Journals (Sweden)

Marcello Manfredi

2016-01-01

Full Text Available Today the long-term conservation of cultural heritage is a big challenge: often the artworks were subjected to unknown interventions, which eventually were found to be harmful. The noninvasive investigation of the conservation treatments to which they were subjected to is a crucial step in order to undertake the best conservation strategies. We describe here the preliminary results on a quick and direct method for the nondestructive identification of the various interventions of parchment by means of direct analysis in real time (DART ionization and high-resolution time-of-flight mass spectrometry and chemometrics. The method has been developed for the noninvasive analysis of the Dead Sea Scrolls, one of the most important archaeological discoveries of the 20th century. In this study castor oil and glycerol parchment treatments, prepared on new parchment specimens, were investigated in order to evaluate two different types of operations. The method was able to identify both treatments. In order to investigate the effect of the ion source temperature on the mass spectra, the DART-MS analysis was also carried out at several temperatures. Due to the high sensitivity, simplicity, and no sample preparation requirement, the proposed analytical methodology could help conservators in the challenging analysis of unknown treatments in cultural heritage.

Radiotherapy as a conservative treatment in breast cancer

International Nuclear Information System (INIS)

Pfuhl, O.R. von; Miola, U.J.; Campos, J.C.F. de

1977-01-01

The review of 545 cases of cancer of the breast, 10% of which were treated by exclusive radiotherapy, emphasized the trend towards conservative treatment, because 29,8% of mastectomized women died within two years from the operation with distant metastases. As it is possible with radiotherapy to cause fibrosis or keep inactive breast tumors up to 5 cm diameter for two years or longer, one must consider irradiation as a good option for young women with small tumors. A combination was used of tangencial radiotherapy up to 5.000 rads to the whole breast with a boost dose two weeks later of 3.000 to 4.000 rads by means of intersticial radiotherapy given only to the palpable tumor. This was fulfilled by the afterloading method according to a system described as geometrization of the breast by parallel plates where holes were drilled for the needles. No recurrence was seen in 4 years in the selected group of 12 patients submitted to the mentioned treatment [pt

Nine breast angiosarcomas after conservative treatment for breast carcinoma: a survey from French Comprehensive Cancer Centers

International Nuclear Information System (INIS)

Marchal, Christian; Weber, Beatrice; Lafontan, Brigitte de; Resbeut, Michel; Mignotte, Herve; Pabot du Chatelard, Pierre; Cutuli, Bruno; Reme-saumon, Monique; Broussier-leroux, Agnes; Chaplain, Gilles; Lesaunier, Francois; Dilhuydy, Jean-Marie; Lagrange, Jean Leon

1999-01-01

Objectives: To conduct a survey of the angiosarcomas developing after breast conservation for carcinoma in the French Cancer Centers, to study the evolution of these cases in detail, and to review literature in an attempt to propose an optimal treatment scheme. Material and Methods: Eleven of the 20 French Cancer Centers agreed to research and retrospectively analyze all angiosarcomas discovered in patients previously treated by conservative treatment. The majority of the patients were node negative, T1N0M0. The mean age of the patients at the time of primary breast cancer treatment was 62.5 years, and 69 years at the diagnosis of the angiosarcoma. Results: During the last two decades, nearly 20,000 patients have been treated conservatively in these 11 centers, and only 9 cases of angiosarcoma were found. The median latency period between the treatment of the breast carcinoma and the diagnosis of the breast angiosarcoma was approximately 74 months, with a range of 57-108 months. Mastectomy was performed as the main treatment of this angiosarcoma. All recurrences after mastectomy for the angiosarcoma appeared within 16 months after the mastectomy. A median time of recurrence was found to be 7.5 months, regardless of the treatment. The angiosarcomas appeared to be very aggressive, and chemotherapy, radiotherapy, and sometimes hyperthermia could only palliate the condition for a short time. After the diagnosis of angiosarcoma, the median survival was 15.5 months, showing a particularly poor prognosis. Only 1 patient of 9 is alive without progressive disease at 32 months after salvage mastectomy for the recurrence of the angiosarcoma. Precise data obtained from 11 centers show that, of 18115 breast carcinomas treated conservatively, only 9 breast angiosarcomas are reported, which represents a prevalence of 5 cases of angiosarcoma per 10,000, which is the same prevalence for primary breast angiosarcomas occurring in healthy breasts. Conclusion: Angiosarcoma developing

The power of Virtual Globes for valorising cultural heritage and enabling sustainable tourism: NASA World Wind applications

Science.gov (United States)

Brovelli, M.; Hogan, P.; Minghini, M.; Zamboni, G.

2013-10-01

Inspired by the visionary idea of Digital Earth, as well as from the tremendous improvements in geo-technologies, use of virtual globes has been changing the way people approach to geographic information on the Web. Unlike the traditional 2D-visualization typical of Geographic Information Systems (GIS), virtual globes offer multi-dimensional, fully-realistic content visualization which allows for a much richer user experience. This research investigates the potential for using virtual globes to foster tourism and enhance cultural heritage. The paper first outlines the state of the art for existing virtual globes, pointing out some possible categorizations according to license type, platform-dependence, application type, default layers, functionalities and freedom of customization. Based on this analysis, the NASA World Wind virtual globe is the preferred tool for promoting tourism and cultural heritage. This is because its open source nature allows unlimited customization (in terms of both data and functionalities), and its Java core supports platform-independence. Relevant tourism-oriented World Wind-based applications, dealing with both the Web promotion of historical cartography and the setup of a participatory Web platform exploiting crowd-sourced data, are described. Finally, the paper presents a project focusing on the promotion of the Via Regina area (crossing the border between Italy and Switzerland) through an ad hoc World Wind customization. World Wind can thus be considered an ideal virtual globe for tourism applications, as it can be shaped to increase awareness of cultural history and, in turn, enhance touristic experience.

Conservative treatment of type B aortic intramural hematoma with no calcification

International Nuclear Information System (INIS)

Wang Zhiwei; Wang Jiaxiang; Li Zhen; Guan Sheng; Wang Leiyong

2014-01-01

Objective: To investigate the effect of conservative treatment for type B aortic intramural hematoma with no calcification, and to discuss the medium-term follow-up results. Methods: During the period from March 2009 to March 2012, a total of 21 patients with type B aortic intramural hematoma without calcification on the aortic wall were admitted to authors' hospital. The diagnosis was confirmed by CT angiography in all patients. Drug therapy was carried out in all the 21 patients, and all the patients were followed up for one year. At 3, 6 and 12 months after the treatment, CT angiography of the aorta was performed to check the results. Results: Of the 21 patients, one received TEVAR therapy one week after the start of drug therapy and the remaining 20 accomplished the whole medication course. At the time of discharge, all the patients were asymptomatic. All the patients were alive up to the end of the following-up period and no recurrence was observed. Three months after the treatment, complete disappearance of the left pleural effusion was obtained in 11 patients, and complete absorption of the intramural hematoma was seen in 3 patients. Six months after the treatment, complete absorption of the intramural hematoma was found in 13 cases. One year after the treatment, complete absorption of the intramural hematoma was confirmed in 19 patients, and in the remaining two patients both the thickness and extent of the intramural hematoma were markedly improved. Conclusion: It is easy to determine whether there is calcification or not in aortic wall of the diseased segment in patients with Stanford type B aortic intramural hematoma. Strict conservative treatment has satisfactory medium-term therapeutic results for type B aortic intramural hematoma with no calcification on the aortic wall. (authors)

The Globe. Neighbourhood Agenda 21: Going Local in Reading.

Science.gov (United States)

Welsh, Richard

1994-01-01

Reports on the philosophy underlying a project to promote local community involvement in neighborhood plans as a basis for a citywide Local Agenda 21 and the first stages of Go Local on a Better Environment (GLOBE) introduced to give the project a popular identify and communicate the environmental message. (LZ)

Humane Orientation as a New Cultural Dimension of the GLOBE Project

DEFF Research Database (Denmark)

Schlösser, Oliver; Frese, Michael; Heintze, Anna-Maria

2013-01-01

We validate, extend, and empirically and theoretically criticize the cultural dimension of humane orientation of the project GLOBE (Global Leadership and Organizational Behavior Effectiveness Research Program). Theoretically, humane orientation is not just a one-dimensionally positive concept about...... study used student samples from 25 countries that were either high or low in humane orientation (N = 876) and studied their relation to the traditional GLOBE scale and other cultural-level measures (agreeableness, religiosity, authoritarianism, and welfare state score). Findings revealed a strong...... correlation between humane orientation and agreeableness, welfare state score, and religiosity. Out-group humane orientation proved to be the more relevant subfacet of the original humane orientation construct, suggesting that future research on humane orientation should make use of this measure instead...

Resource Conservation and Recovery Act (RCRA) closure sumamry for the Uranium Treatment Unit

International Nuclear Information System (INIS)

1996-05-01

This closure summary has been prepared for the Uranium Treatment Unit (UTU) located at the Y-12 Plant in Oak Ridge, Tennessee. The actions required to achieve closure of the UTU area are outlined in the Closure Plan, submitted to and approved by the Tennessee Department of Environmental and Conservation staff, respectively. The UTU was used to store and treat waste materials that are regulated by the Resource Conservation and Recovery Act. This closure summary details all steps that were performed to close the UTU in accordance with the approved plan

Conservation-reuse of water in fossil-fuel power plants including water treatment plants

Energy Technology Data Exchange (ETDEWEB)

Rao, T.S.R.

1984-02-01

The various areas where the conservation-reuse of water is possible are discussed. However, water conservation, especially effluent volume reduction-treatment reuse, should be seen in the light of pollution control measures. Some of the areas indicated recover a small quantity of water but they should be viewed in the light of well yield being not adequate, or having high salinity or having an increase of well water salinity after some use. Some of the methods can only be adopted at the design stage whereas others could be incorporated at the site.

Monitoring the effects of different conservation treatments on paper-infecting fungi.

Science.gov (United States)

Michaelsen, Astrid; Pinzari, Flavia; Barbabietola, Nicoletta; Piñar, Guadalupe

2013-10-01

Fungi are among the most degradative organisms inducing biodeterioration of paper-based items of cultural heritage. Appropriate conservation measures and restoration treatments to deal with fungal infections include mechanical, chemical, and biological methods, which entail effects on the paper itself and health hazards for humans. Three different conservation treatments, namely freeze-drying, gamma rays, and ethylene oxide fumigation, were compared and monitored to assess their short- (one month, T1) and long-term (one year, T2) effectiveness to inhibit fungal growth. After the inoculation with fungi possessing cellulose hydrolysis ability - Chaetomium globosum , Trichoderma viride, and Cladosporium cladosporioides - as single strains or as a mixture, different quality paper samples were treated and screened for fungal viability by culture-dependent and -independent techniques. Results derived from both strategies were contradictory. Both gamma irradiation and EtO fumigation showed full efficacy as disinfecting agents when evaluated with cultivation techniques. However, when using molecular analyses, the application of gamma rays showed a short-term reduction in DNA recovery and DNA fragmentation; the latter phenomenon was also observed in a minor degree in samples treated with freeze-drying. When RNA was used as an indicator of long-term fungal viability, differences in the RNA recovery from samples treated with freeze-drying or gamma rays could be observed in samples inoculated with the mixed culture. Only the treatment with ethylene oxide proved negative for both DNA and RNA recovery. Therefore, DNA fragmentation after an ethylene oxide treatment can hamper future paleogenetic and archaeological molecular studies on the objects.

Effectiveness of conservative treatment for patellofemoral pain syndrome: A systematic review and meta-analysis

Directory of Open Access Journals (Sweden)

Mikhail Saltychev

2018-01-01

Full Text Available Objective: To evaluate the evidence regarding the effectiveness of conservative treatment in reducing patellofemoral pain. Data sources: CENTRAL, MEDLINE, CINAHL, and PEDro databases. Study selection: Adults with patellofemoral pain, randomized controlled trials only, any conservative treatment compared with placebo, sham, other conservative treatment, or no treatment. Two independent reviewers. Data extraction: Data were extracted from the full-text of the articles, based on Cochrane Collaboration recommendations. The outcome of interest was the difference between groups regarding change in pain severity. Data synthesis: The majority of studies were underpowered. More than 80% of the 37 trials did not show a clinically significant benefit. Clinically significant effects of different sizes were found for 7 trials (6 studies out of 7 had short follow-ups. These effects were found for: (i pulsed electromagnetic fields combined with home exercise –33.0 (95% CI –45.2 to –20.8; (ii hip muscle strengthening –65.0 (95% CI –87.7 to –48.3 and –32.0 (–37.0 to –27.0; (iii weight-bearing exercise –40.0 (95% CI –49.4 to –30.6; (iv neuromuscular facilitation combined with aerobic exercise and stretching –60.1 (95% CI –66.9 to –54.5; (v postural stabilization –24.4 (95% CI –33.5 to –15.3; and (vi patellar bracing –31.6 (95% CI –35.2 to –28.0. Conclusion: There is no evidence that a single treat-ment modality works for all patients with patellofemoral pain. There is limited evidence that some treatment modalities may be beneficial for some subgroups of patients with patellofemoral pain.

The conservative treatment of pediatric mandibular fracture with prefabricated surgical splint: a case report.

Science.gov (United States)

Kocabay, Ceyda; Ataç, Mustafa Sancar; Oner, Burak; Güngör, Nadir

2007-08-01

The use of rigid fixation in children is controversial and may cause growth retardation along cranial suture lines. Intermaxillary fixation for mandibular fractures should be used cautiously as bony ankylosis in the temporomandibular joint (TMJ) and trismus may develop. The high osteogenic potential of the pediatric mandible allows non-surgical management to be successful in younger patients with conservative approaches. In this case, successful conservative treatment of mandibular fracture of a 3-year-old patient is presented.

In Vitro Callogenesis and Agrobacterium-Mediated Transformation of Globe Artichoke

NARCIS (Netherlands)

Menin, B.; Moglia, A.; Comino, C.; Lanteri, S.; Herpen, van T.W.J.M.; Beekwilder, M.J.

2012-01-01

Micropropagation techniques have been widely applied in globe artichoke (C. cardunculus L. var. scolymus), however, efficient protocols for the establishment of in vitro callogenesis and organogenesis, a pre-requisite for Agrobacterium-mediated genetic transformation, have not been set up so far. We

Inauguration of the Globe of Science and Innovation

CERN Multimedia

Patrice Loiez; Michel Blanc

2004-01-01

The building formerly known as 'Palais de l'Equilibre' has been given to CERN by the Swiss Confederation to mark the Laboratory's 50th Anniversary. The impressive 28 m high, 40 m diameter sphere was built by a consortium of 11 Swiss companies who specialise in timber construction. The Globe is a symbol for sustainable development: it is constructed entirely from wood and its circular form represents planet Earth.

Construction of a reference molecular linkage map of globe artichoke (Cynara cardunculus var. scolymus).

Science.gov (United States)

Portis, E; Mauromicale, G; Mauro, R; Acquadro, A; Scaglione, D; Lanteri, S

2009-12-01

The genome organization of globe artichoke (Cynara cardunculus var. scolymus), unlike other species belonging to Asteraceae (=Compositae) family (i.e. sunflower, lettuce and chicory), remains largely unexplored. The species is highly heterozygous and suffers marked inbreeding depression when forced to self-fertilize. Thus a two-way pseudo-testcross represents the optimal strategy for linkage analysis. Here, we report linkage maps based on the progeny of a cross between globe artichoke (C. cardunculus var. scolymus) and cultivated cardoon (C. cardunculus var. altilis). The population was genotyped using a variety of PCR-based marker platforms, resulting in the identification of 708 testcross markers suitable for map construction. The male map consisted of 177 loci arranged in 17 major linkage groups, spanning 1,015.5 cM, while female map was built with 326 loci arranged into 20 major linkage groups, spanning 1,486.8 cM. The presence of 84 loci shared between these maps and those previously developed from a cross within globe artichoke allowed for map alignment and the definition of 17 homologous linkage groups, corresponding to the haploid number of the species. This will provide a favourable property for QTL scanning; furthermore, as 25 mapped markers (8%) correspond to coding regions, it has an additional value as functional map and might represent an important genetic tool for candidate gene studies in globe artichoke.

Closed chamber globe stabilization and needle capsulorhexis using irrigation hand piece of bimanual irrigation and aspiration system

Directory of Open Access Journals (Sweden)

Rai Harminder K

2005-08-01

Full Text Available Abstract Background The prerequisites for a good capsulorhexis include a deep, well maintained anterior chamber, globe stabilization and globe manipulation. This helps to achieve a capsulorhexis of optimal size, shape and obtain the best possible position for a red glow under retroillumination. We report the use of irrigation handpiece of bimanual irrigation aspiration system to stabilize the globe, maintain a deep anterior chamber and manipulate the globe to a position of optimal red reflex during needle capsulorhexis in phacoemulsification. Methods Two side ports are made with 20 G MVR 'V' lance knife (Alcon, USA. The irrigation handpiece with irrigation on is introduced into the anterior chamber through one side port and the 26-G cystitome (made from 26-G needle is introduced through the other. The capsolurhexis is completed with the needle. Results Needle capsulorhexis with this technique was used in 30 cases of uncomplicated immature senile cataracts. 10 cases were done under peribulbar anaesthesia and 20 under topical anaesthesia. A complete capsulorhexis was achieved in all cases. Conclusion The irrigating handpiece maintains deep anterior chamber, stabilizes the globe, facilitates pupillary dilatation, and helps in maintaining the eye in the position with optimal red reflex during needle capsulorhexis. This technique is a safe and effective way to perform needle capsulorhexis.

Ülevaade GLOBE'i programmi tööst Eestis / Imbi Henno

Index Scriptorium Estoniae

Henno, Imbi

2001-01-01

GLOBE (Global Learning and Observations to Benefit Environment) on üldhariduskoolidele mõeldud keskkonnasuunitlusega haridus- ja teadusprogramm, mis ühendab lapsi, õpetajaid ja teadlasi kogu maailmast

Irradiation treatment for the protection and conservation of cultural heritage artefacts in Croatia

International Nuclear Information System (INIS)

Katusin-Razem, Branka; Razem, Dusan; Braun, Mario

2009-01-01

The application of irradiation treatment for the protection of cultural heritage artefacts in Croatia was made possible by the development of radiation processing procedures at the Radiation Chemistry and Dosimetry Laboratory of the Ruder Boskovic Institute. After the upgrading of the 60 Co gamma irradiation source in the panoramic irradiation facility in 1983 it became possible to perform both research and pilot plant-scale irradiations for sterilization, pasteurization and decontamination of various materials, including medical supplies, pharmaceuticals, cosmetics and foods, but also for disinfestation of cultural heritage artefects. The demand for irradiation treatment of cultural heritage objects has particularly increased as the increasing number of these objects, especially polychromic wooden sculptures, were requiring salvation, restauration and conservation as a consequence of direct and indirect damages inflicted to them during the war in Croatia, 1991-1995. The irradiation facility at the Ruder Boskovic Institute is briefly described and an account of its fifteen years' activities in the irradiation treatment of cultural heritage objects is given. Some case studies performed in cooperation with the Croatian Conservation Institute and other interested parties are presented, as well as some cases of protective and curative treatments for disinfestation and decontamination. International cooperations and activities are also mentioned.

Irradiation treatment for the protection and conservation of cultural heritage artefacts in Croatia

Energy Technology Data Exchange (ETDEWEB)

Katusin-Razem, Branka [Department of Chemistry, Ruder Boskovic Institute, Bijenicka cesta 54, P.O. Box 180, HR-10002 Zagreb (Croatia)], E-mail: brazem@irb.hr; Razem, Dusan [Department of Chemistry, Ruder Boskovic Institute, Bijenicka cesta 54, P.O. Box 180, HR-10002 Zagreb (Croatia); Braun, Mario [Croatian Conservation Institute, Zagreb (Croatia)

2009-07-15

The application of irradiation treatment for the protection of cultural heritage artefacts in Croatia was made possible by the development of radiation processing procedures at the Radiation Chemistry and Dosimetry Laboratory of the Ruder Boskovic Institute. After the upgrading of the {sup 60}Co gamma irradiation source in the panoramic irradiation facility in 1983 it became possible to perform both research and pilot plant-scale irradiations for sterilization, pasteurization and decontamination of various materials, including medical supplies, pharmaceuticals, cosmetics and foods, but also for disinfestation of cultural heritage artefects. The demand for irradiation treatment of cultural heritage objects has particularly increased as the increasing number of these objects, especially polychromic wooden sculptures, were requiring salvation, restauration and conservation as a consequence of direct and indirect damages inflicted to them during the war in Croatia, 1991-1995. The irradiation facility at the Ruder Boskovic Institute is briefly described and an account of its fifteen years' activities in the irradiation treatment of cultural heritage objects is given. Some case studies performed in cooperation with the Croatian Conservation Institute and other interested parties are presented, as well as some cases of protective and curative treatments for disinfestation and decontamination. International cooperations and activities are also mentioned.

Comparison of percutaneous coronary intervention versus conservative treatment in unstable angina pectoris

International Nuclear Information System (INIS)

Hu Chunyan; Lv Bei; Shen Weifeng; Lu Guoping

2002-01-01

Objective: To evaluate the efficacies of percutaneous coronary intervention (PCI) and drug treatment in patients with unstable angina (UAP). Methods: 248 patients with UAP were divided into two groups: conservative group of 123 patients who received antiplatelet, anticoagulant and antianginal therapies only and invasive group of 125 patients who underwent additional PCI 4.4 days after admission. The occurrence of death, AMI, recurrent angina, readmission were assessed during the first hospitalization year. Results: There was no difference in the incidence of composite endpoint of death or AMI between the two groups during the hospitalization (0.8 % vs 1.6 %, P > 0.05 ), but hospitalization duration was shorter in the invasive group than in the conservative group (10.3 ± 5.6 days vs 14.6 ± 10.7 days, P < 0.01 ). In duration of one year, the incidence of AMI (2.4% vs 8.9%, P<0.03), death (1.6% vs 6.5%, P<0.05), composite endpoint of death or AMI (4.0 % vs 13.0 % P < 0.02), recurrent angina pectoris (26.4 % vs 48.7, P <0.001), CABG (1.6% vs 10.5%, P<0.01) and readmission (24.8% vs 45.5%, P<0.01) were also lower in the invasive group than in the conservative group. Survival rate free of composite death or AMI for 1 year was higher in the invasive group than in the conservative group(96.0 % vs 86.9 %, P < 0.02). There was a definite benefit of the invasive treatment in reducing the risk of composite endpoint of death or AMI in patients with chest pain at rest, troponin T positive and three vessel diseases. Old age, three vessel diseases, LAD disease, lower LVEF, ST-segment depression, diabetes and hypertension were the independent factors associated with composite of death or AMI. Conclusions: In patients with UAP, PCI associated with routine antiplatelet, anticoagulant and antiischemic treatment significantly decreases the incidence of adverse cardiac events and improves the survival rate in one year. Such beneficial effects can be more obvious for high-risk patients

Demographic Characteristics and Clinical Outcome of Work-related Open Globe Injuries in the Most Industrialised Region of Turkey

Directory of Open Access Journals (Sweden)

Sertaç Argun Kıvanç

2017-01-01

Full Text Available Objectives: To evaluate demographic characteristics and clinical outcomes of work-related open globe injuries in the most industrialized region of Turkey. Materials and Methods: The demographic and medical records of patients with work-related open globe injuries who presented to the ophthalmology or emergency departments with an official occupational accident report were retrospectively reviewed. Visual acuity categories were defined according to the World Health Organization. The injury types and zones of the open globes were classified according to Birmingham Eye Trauma Terminology System. Results: Among 479 patients with work-related eye injuries in 5 years, there were 102 eyes of 101 patients with open globe injuries (21%. The mean age of the patients was 34.5±8.9 years with a mean follow-up of 12.5±12.6 months. The injuries peaked in June in the hour between 12:00 and 13:00. Eighty-six percent presented to emergency services within 12 hours after the injury. Twenty-two percent of the patients had been wearing protective eyewear at the time of injury. The open globe injuries were penetrating in 51%, intraocular foreign body in 40%, rupture in 7% and perforation in 2% of the eyes. The most frequent finding was traumatic cataract. Final visual acuity of 33.3% of patients was below 3/60. Seventy-eight percent of patients that had visual acuity worse than 6/18 at presentation had visual acuity of 6/18 or better at final visit. Sixty-three percent of eyes which had injuries involving all 3 zones resulted in phthisis bulbi, enucleation or evisceration. Conclusion: Work-related open globe injuries may have severe consequences such as visual impairment and blindness among the young male working population in industrialized areas. Nearly half of the occupational open globe injuries resulted in visual impairment and blindness.

Hospitalization, frequency of interventions, and quality of life after endoscopic, surgical, or conservative treatment in patients with chronic pancreatitis.

Science.gov (United States)

Rutter, Karoline; Ferlitsch, A; Sautner, T; Püspök, A; Götzinger, P; Gangl, A; Schindl, M

2010-11-01

Patients with chronic pancreatitis usually have a long and debilitating history of disease with frequent hospital admissions, episodes of intractable pain and multiple interventions. The sequences of treatment at initial presentation, endoscopy, surgery, or conservative treatment may affect the time course and admissions needed for disease control, thereby determining quality of life and overall outcome. A total of 292 patients with initial endoscopic, surgical, or conservative pharmacological treatment were retrospectively analyzed regarding frequency of interventions, days in hospital, symptom-free intervals, morbidity, and mortality. Quality of life (QoL) at the latest follow-up was measured by two standardized quality of life questionnaires (EORTC C30 and PAN26). Endoscopic treatment was initially performed in 150 (51.4%) patients, whereas 99 (33.9%) underwent surgery and 43 (14.7%) patients were treated conservatively at their initial presentation. Patients who underwent surgery had a significantly shorter time in the hospital (25.3 ± 24.6, 34.4 ± 35.1, 61.1 ± 37.9; P surgical treatment (P ≤ 0.001), whereas patients after endoscopic intervention developed acute or chronic pancreatitis or pseudocyst formation (P = 0.023). Patients who undergo surgery as their initial treatment for chronic pancreatitis require less consecutive interventions, a shorter hospital stay, and have a better quality of life compared with any other treatment. Surgery should therefore be considered early for the treatment of chronic pancreatitis, when endoscopic or conservative treatment fails and patients require further intervention.

Yrityksen näkyvyyden lisääminen sosiaalisessa mediassa, Case Globe Hope

OpenAIRE

Asikainen, Miisa

2016-01-01

Opinnäytetyön tarkoituksena oli selvittää, kuinka lisätään näkyvyyttä jo olemassa olevan yrityksen sosiaalisen median kanavien aktivoimisella. Työn toimeksianto tuli suomalaiselta Globe Hope –nimiseltä design-alan yritykseltä. Globe Hope valmistaa tuotteensa kierrätys- sekä ylijäämämateriaaleista. Sosiaalisen median markkinoinnin tutkimus sekä opinnäytetyöntekijän opinnot muotimarkkinoinnin parissa toimivat työn pohjana. Työn tavoite oli selvittää erilaisia keinoja kasvattaa näkyvyyttä sosiaa...

Transcatheter arterial embolization of abnormal vessels as a treatment for lateral epicondylitis refractory to conservative treatment: a pilot study with a 2-year follow-up.

Science.gov (United States)

Iwamoto, Wataru; Okuno, Yuji; Matsumura, Noboru; Kaneko, Takao; Ikegami, Hiroyasu

2017-08-01

Abnormal vessels and accompanying nerves are possible sources of pain with lateral epicondylitis. The purpose of this study was to describe the safety and efficacy of transcatheter arterial embolization (TAE) for lateral epicondylitis resistant to conservative treatment. This prospective study was conducted in 24 patients with lateral epicondylitis resistant to conservative treatments for more than 3 months, with a symptom duration longer than 6 months, and with moderate to severe pain who were treated with TAE between March 2013 and October 2014. Two patients were lost to follow-up, and the remaining 22 patients were followed up for 2 years after TAE. Abnormal vessels were identified in all of the patients. No major adverse events were observed. The Quick Disabilities of the Arm, Shoulder and Hand scores at baseline significantly decreased at 1, 3, 6, and 24 months after treatment (50.8 vs 23.4, 8.3, 5.3, and 2.7, respectively; all P lateral epicondylitis that fails to improve with conservative treatments. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Breast conserving surgery in locoregional treatment of breast carcinoma after Hodgkin lymphoma

International Nuclear Information System (INIS)

Haberer, S.; Le Scodan, R.; Kirova, Y.M.; Moisson, P.; Campana, F.; Fourquet, A.; Bollet, M.A.; Belin, L.; Savignoni, A.; Stevens, D.; Decaudin, D.; Pierga, J.Y.; Reyal, F.

2012-01-01

Purpose. - To report characteristics and outcome of breast cancer after irradiation for Hodgkin lymphoma with special focus on breast conservation surgery. Patients and methods. - Medical records of 72 women who developed either ductal carcinoma in situ or stage I-III invasive carcinoma of the breast after Hodgkin lymphoma between 1978 and 2009 were retrospectively reviewed. Results. - Median age at Hodgkin lymphoma diagnosis was 23 years old. Median total dose received by the mediastinum was 40 Gy, mostly by a mantle field technique. Breast cancer occurred after a median time interval of 21 years. Ductal invasive carcinoma and ductal carcinoma in situ represented respectively 71% and 19% of the cases. Locoregional treatment for breast cancer consisted of mastectomy with or without radiotherapy in 39 patients and of lumpectomy with or without adjuvant radiotherapy in 32 patients. The isocentric lateral decubitus radiation technique was used in 17 patients after breast conserving surgery (57%). With a median follow-up of 7 years, 5-year overall survival rate and locoregional control rate were respectively 74.5% and 82% for invasive carcinoma and 100% and 92% for in situ carcinoma. Thirteen patients died of progressive breast cancer and contralateral breast cancer was diagnosed in ten patients (14%). Conclusions. - Breast conserving treatment can be an option for breast cancers that occur after Hodgkin lymphoma despite prior thoracic irradiation. It should consist of lumpectomy and adjuvant breast radiotherapy with use of adequate techniques, such as the lateral decubitus isocentric position. (authors)

Impact of combinatory growth factor application on rabbit Achilles tendon injury with operative versus conservative treatment: a pilot study.

Science.gov (United States)

Konerding, Moritz A; Arlt, Friederike; Wellmann, Axel; Li, Vincent; Li, William

2010-02-01

Acute Achilles tendon (AT) rupture is a common injury with a comparatively high complication rate. Presently, surgical treatments compete with nonoperative treatment modalities. The aim of this study was to elucidate the possible beneficial effects of short-term combinatory application of growth factors on tendon healing during operative or conservative treatment. In this controlled laboratory study, the left ATs of 40 adult New Zealand White rabbits were transected and either sutured or treated conservatively. Half of the animals from each treatment modality group repetitively received a mixture of VEGF165, bFGF, and rPDGF which was administered peritendineally. The left legs were immobilized with external fixateurs for 6 weeks. The ATs were harvested 3 months after intervention. Tensile strength tests revealed no significant differences between operative and conservative treatments. Compared to the normal right ATs, 60% of the average breaking strength was reached 3 months after surgery. Growth factor application did not result in significant improvements. Only a tendency towards higher blood vessel densities was noted in the groups treated with the factors. Collagen type I/III ratios also displayed no significant differences. This study indicates that there is no difference in the biomechanical outcome of conservative versus operative AT rupture treatment and only a marginal impact of short-term combinatory growth and angiogenesis factor application.

The genome-wide identification and transcriptional levels of DNA methyltransferases and demethylases in globe artichoke.

Science.gov (United States)

Gianoglio, Silvia; Moglia, Andrea; Acquadro, Alberto; Comino, Cinzia; Portis, Ezio

2017-01-01

Changes to the cytosine methylation status of DNA, driven by the activity of C5 methyltransferases (C5-MTases) and demethylases, exert an important influence over development, transposon movement, gene expression and imprinting. Three groups of C5-MTase enzymes have been identified in plants, namely MET (methyltransferase 1), CMT (chromomethyltransferases) and DRM (domains rearranged methyltransferases). Here the repertoire of genes encoding C5-MTase and demethylase by the globe artichoke (Cynara cardunculus var. scolymus) is described, based on sequence homology, a phylogenetic analysis and a characterization of their functional domains. A total of ten genes encoding C5-MTase (one MET, five CMTs and four DRMs) and five demethylases was identified. An analysis of their predicted product's protein structure suggested an extensive level of conservation has been retained by the C5-MTases. Transcriptional profiling based on quantitative real time PCR revealed a number of differences between the genes encoding maintenance and de novo methyltransferases, sometimes in a tissue- or development-dependent manner, which implied a degree of functional specialization.

The genome-wide identification and transcriptional levels of DNA methyltransferases and demethylases in globe artichoke.

Directory of Open Access Journals (Sweden)

Silvia Gianoglio

Full Text Available Changes to the cytosine methylation status of DNA, driven by the activity of C5 methyltransferases (C5-MTases and demethylases, exert an important influence over development, transposon movement, gene expression and imprinting. Three groups of C5-MTase enzymes have been identified in plants, namely MET (methyltransferase 1, CMT (chromomethyltransferases and DRM (domains rearranged methyltransferases. Here the repertoire of genes encoding C5-MTase and demethylase by the globe artichoke (Cynara cardunculus var. scolymus is described, based on sequence homology, a phylogenetic analysis and a characterization of their functional domains. A total of ten genes encoding C5-MTase (one MET, five CMTs and four DRMs and five demethylases was identified. An analysis of their predicted product's protein structure suggested an extensive level of conservation has been retained by the C5-MTases. Transcriptional profiling based on quantitative real time PCR revealed a number of differences between the genes encoding maintenance and de novo methyltransferases, sometimes in a tissue- or development-dependent manner, which implied a degree of functional specialization.

Restricted-range fishes and the conservation of Brazilian freshwaters.

Science.gov (United States)

Nogueira, Cristiano; Buckup, Paulo A; Menezes, Naercio A; Oyakawa, Osvaldo T; Kasecker, Thais P; Ramos Neto, Mario B; da Silva, José Maria C

2010-06-30

Freshwaters are the most threatened ecosystems on earth. Although recent assessments provide data on global priority regions for freshwater conservation, local scale priorities remain unknown. Refining the scale of global biodiversity assessments (both at terrestrial and freshwater realms) and translating these into conservation priorities on the ground remains a major challenge to biodiversity science, and depends directly on species occurrence data of high taxonomic and geographic resolution. Brazil harbors the richest freshwater ichthyofauna in the world, but knowledge on endemic areas and conservation in Brazilian rivers is still scarce. Using data on environmental threats and revised species distribution data we detect and delineate 540 small watershed areas harboring 819 restricted-range fishes in Brazil. Many of these areas are already highly threatened, as 159 (29%) watersheds have lost more than 70% of their original vegetation cover, and only 141 (26%) show significant overlap with formally protected areas or indigenous lands. We detected 220 (40%) critical watersheds overlapping hydroelectric dams or showing both poor formal protection and widespread habitat loss; these sites harbor 344 endemic fish species that may face extinction if no conservation action is in place in the near future. We provide the first analysis of site-scale conservation priorities in the richest freshwater ecosystems of the globe. Our results corroborate the hypothesis that freshwater biodiversity has been neglected in former conservation assessments. The study provides a simple and straightforward method for detecting freshwater priority areas based on endemism and threat, and represents a starting point for integrating freshwater and terrestrial conservation in representative and biogeographically consistent site-scale conservation strategies, that may be scaled-up following naturally linked drainage systems. Proper management (e. g. forestry code enforcement, landscape

Effect of bracing and other conservative interventions in the treatment of idiopathic scoliosis in adolescents : A systematic review of clinical trials

NARCIS (Netherlands)

Lenssinck, MLB; Frijlink, AC; Berger, MY; Bierma-Zeinstra, SMA; Verkerk, K; Verhagen, AP

2005-01-01

Background and Purpose. Many conservative treatments are available for adolescents with idiopathic scoliosis, but the evidence for their accepted use is still unclear. The purpose of this study was to evaluate the effectiveness of braces and other conservative treatments of idiopathic scoliosis in

Heavenly Networks. Celestial Maps and Globes in Circulation between Artisans, Mathematicians, and Noblemen in Renaissance Europe.

Science.gov (United States)

Gessner, Samuel

2015-01-01

The aim of this paper is to examine the iconography on a set of star charts by Albrecht Dürer (1515), and celestial globes by Caspar Vopel (1536) and Christoph Schissler (1575). The iconography on these instruments is conditioned by strong traditions which include not only the imagery on globes and planispheres (star charts), but also ancient literature about the constellations. Where this iconography departs from those traditions, the change had to do with humanism in the sixteenth century. This "humanistic" dimension is interwoven with other concerns that involve both "social" and "technical" motivations. The interplay of these three dimensions illustrates how the iconography on celestial charts and globes expresses some features of the shared knowledge and shared culture between artisans, mathematicians, and nobles in Renaissance Europe.

Cosmetic results of conservative treatment for early breast cancer

International Nuclear Information System (INIS)

Kim, Bo Kyoung; Shin, Seong Soo; Kim, Seong Deok; Ha, Sung Whan; Noh, Dong Young

2001-01-01

This study was performed to evaluate the cosmetic outcome of conservative treatment for early breast cancer and to analyze the factors influencing cosmetic outcome. From February 1992 through January 1997, 120 patients with early breast cancer were treated with conservative surgery and postoperative radiotherapy. The types of conservative surgery were quadrantectomy and axillary node dissection for 108 patients (90%) and lumpectomy or excisional biopsy for 10 patients (8.3%). Forty six patients (38%) received adjuvant chemotherapy (CMF or CAF). Cosmetic result evaluation was carried out between 16 and 74 months (median, 33 months) after surgery. The cosmetic results were classified into four categories, i.e., excellent, good, fair, and poor. The appearances of the patients' breasts were also analyzed for symmetry using the differences in distances from the stemal notch to right and left nipples. A logistic regression analysis was performed to identify independent variables influencing the cosmetic outcome. Cosmetic score was excellent or good in 76% (91/120), fair in 19% (23/120) and poor in 5% (6/ 120) of the patients. Univariate analysis showed that tumor size (T1 versus T2) (p=0.04), axillary node status (NO versus N1) (p=0.0002), extent of surgery (quadrantectomy versus lumpectomy or excisional biopsy) (p=0.02), axillary node irradiation (p=0.0005) and chemotherapy (p=0,0001) affected cosmetic score. Multivariate analysis revealed that extent of surgery (p=0.04) and chemotherapy (p=0.0002) were significant factors. For breast symmetry, univariate analysis confirmed exactly the same factors as above. Multivariate analysis revealed that tumor size (p=0.003) and lymph node status (p=0.007) affected breast symmetry. Conservative surgery and postoperative radiotherapy resulted in excellent or good cosmetic outcome in a large portion of the patients. Better cosmetic results were achieved generally in the group of patients with smaller tumor size, without axillary

Cohort study of lumbar percutaneous chemonucleolysis using ethanol gel in sciatica refractory to conservative treatment

International Nuclear Information System (INIS)

Touraine, Sebastien; Tran, Olivia; Laredo, Jean-Denis; Damiano, Joel

2015-01-01

To investigate the efficacy of percutaneous chemonucleolysis using ethanol gel (PCEG) in alleviating radicular pain due to disc herniation after failure of conservative treatment. After failure of conservative treatment, PCEG was performed under fluoroscopic guidance in 42 patients with sciatica >4/10 on a Visual Analog Scale (VAS) for at least 6 weeks and consistent disc herniation on MRI or CT <3 months. The VAS pain score was determined at baseline, then after 1 and 3 months. We assessed the influence of patient-related factors (age, gender, pain duration) and disc herniation-related factors (level, migration pattern, disc herniation-related spinal stenosis) on outcome of PCEG. Mean pain duration was 6.7 months. Pain intensity decreased by 44 % and 62.6 % after 1 and 3 months, respectively, versus baseline (P = 0.007). A mild improvement was noted by the rheumatologist in 30/42 (71.4 %) and 36/42 (85.7 %) patients after 1 and 3 months, respectively, and in 31/42 (73.8 %) and 33/42 (78.6 %) patients by self-evaluation. Patients who failed PCEG were significantly older (49.8 vs. 37.3 years, P = 0.03). None of the other variables studied were significantly associated with pain relief. PCEG may significantly improve disc-related radicular pain refractory to conservative treatment. (orig.)

Cohort study of lumbar percutaneous chemonucleolysis using ethanol gel in sciatica refractory to conservative treatment

Energy Technology Data Exchange (ETDEWEB)

Touraine, Sebastien; Tran, Olivia; Laredo, Jean-Denis [Hopital Lariboisiere, AP-HP, Radiologie Osteo-Articulaire, Paris Cedex 10 (France); Damiano, Joel [Hopital Lariboisiere, AP-HP, Rhumatologie, Centre Viggo-Petersen, Paris Cedex 10 (France)

2015-11-15

To investigate the efficacy of percutaneous chemonucleolysis using ethanol gel (PCEG) in alleviating radicular pain due to disc herniation after failure of conservative treatment. After failure of conservative treatment, PCEG was performed under fluoroscopic guidance in 42 patients with sciatica >4/10 on a Visual Analog Scale (VAS) for at least 6 weeks and consistent disc herniation on MRI or CT <3 months. The VAS pain score was determined at baseline, then after 1 and 3 months. We assessed the influence of patient-related factors (age, gender, pain duration) and disc herniation-related factors (level, migration pattern, disc herniation-related spinal stenosis) on outcome of PCEG. Mean pain duration was 6.7 months. Pain intensity decreased by 44 % and 62.6 % after 1 and 3 months, respectively, versus baseline (P = 0.007). A mild improvement was noted by the rheumatologist in 30/42 (71.4 %) and 36/42 (85.7 %) patients after 1 and 3 months, respectively, and in 31/42 (73.8 %) and 33/42 (78.6 %) patients by self-evaluation. Patients who failed PCEG were significantly older (49.8 vs. 37.3 years, P = 0.03). None of the other variables studied were significantly associated with pain relief. PCEG may significantly improve disc-related radicular pain refractory to conservative treatment. (orig.)

Conservation and restoration of mangroves: Global status, perspectives, and prognosis

Science.gov (United States)

Romañach, Stephanie; DeAngelis, Donald L.; Koh, Hock Lye; Li, Yuhong; Teh, Su Yean; Barizan, Raja Sulaiman Raja; Zhai, Lu

2018-01-01

Mangrove forests provide critical services around the globe to both human populations and the ecosystems they occupy. However, losses of mangrove habitat of more than 50% have been recorded in some parts of the world, and these losses are largely attributable to human activities. The importance of mangroves and the threats to their persistence have long been recognized, leading to actions taken locally, by national governments, and through international agreements for their protection. In this review, we explore the status of mangrove forests as well as efforts to protect them. We examine threats to the persistence of mangroves, consequences, and potential solutions for effective conservation. We present case studies from disparate regions of the world, showing that the integration of human livelihood needs in a manner that balances conservation goals can present solutions that could lead to long-term sustainability of mangrove forests throughout the world.

A Protocol for Producing Virus-Free Artichoke Genetic Resources for Conservation, Breeding, and Production

Directory of Open Access Journals (Sweden)

Roberta Spanò

2018-03-01

Full Text Available The potential of the globe artichoke biodiversity in the Mediterranean area is enormous but at risk of genetic erosion because only a limited number of varieties are vegetatively propagated and grown. In Apulia (southern Italy, the Regional Government launched specific actions to rescue and preserve biodiversity of woody and vegetable crops in the framework of the Rural Development Program. Many globe artichoke ecotypes have remained neglected and unnoticed for a long time and have been progressively eroded by several causes, which include a poor phytosanitary status. Sanitation of such ecotypes from infections of vascular fungi and viruses may be a solution for their ex situ conservation and multiplication in nursery plants in conformity to the current EU Directives 93/61/CEE and 93/62/CEE that enforce nursery productions of virus-free and true-to-type certified stocks. Five Apulian ecotypes, Bianco di Taranto, Francesina, Locale di Mola, Verde di Putignano and Violetto di Putignano, were sanitized from artichoke Italian latent virus (AILV, artichoke latent virus (ArLV and tomato infectious chlorosis virus (TICV by meristem-tip culture and in vitro thermotherapy through a limited number of subcultures to reduce the risk of “pastel variants” induction of and loss of earliness. A total of 25 virus-free primary sources were obtained and conserved ex situ in a nursery.

Astronomy Meets the Environmental Sciences: Using GLOBE at Night Data

Science.gov (United States)

Barringer, D.; Walker, C. E.; Pompea, S. M.; Sparks, R. T.

2011-09-01

The GLOBE at Night database now contains over 52,000 observations from the five annual two-week campaigns. It can be used as a resource to explore various issues related to light pollution and our environment. Students can compare data over time to look for changes and trends. For example, they can compare the data to population density or with nighttime photography and spectroscopy of lights. The data can be used in a lighting survey, to search for dark sky oases or to monitor ordinance compliance. Students can study effects of light pollution on animals, plants, human health, safety, security, energy consumption, and cost. As an example, we used data from the GLOBE at Night project and telemetry tracking data of lesser long-nosed bats obtained by the Arizona Game and Fish Department to study the effects of light pollution on the flight paths of the bats between their day roosts and night foraging areas around the city of Tucson, AZ. With the visual limiting magnitude data from GLOBE at Night, we ran a compositional analysis with respect to the bats' flight paths to determine whether the bats were selecting for or against flight through regions of particular night sky brightness levels. We found that the bats selected for the regions in which the limiting sky magnitudes fell between the ranges of 2.8-3.0 to 3.6-3.8 and 4.4-4.6 to 5.0-5.2, suggesting that the lesser long-nosed bat can tolerate a fair degree of urbanization. We also compared this result to contour maps created with digital Sky Quality Meter (http://www.unihedron.com) data.

Globe at Night: From IYA2009 to the International Year of Light 2015 and Beyond

Science.gov (United States)

Walker, Constance Elaine; Pompea, Stephen M.; Sparks, Robert T.

2015-08-01

Citizen-science is a rewardingly inclusive way to bring awareness to the public on important issues like the disappearing starry night sky, its cause and solutions. Citizen-science can also provide meaningful, hands-on “science process” experiences for students. One program that does both is Globe at Night (www.globeatnight.org), an international campaign to raise public awareness of the impact of light pollution by having people measure night-sky brightness and submit observations via a “web app” on any smart device or computer. Additionally, 2 native mobile apps - Loss of the Night for iPhone & Android, and Dark Sky Meter for iPhone - support Globe at Night.Since 2006, more than 125,000 vetted measurements from 115 countries have been reported. For 2015 the campaign is offered as a 10-day observation window each month when the Moon is not up. To facilitate Globe at Night as an international project, the web app and other materials are in many languages. (See www.globeatnight.org/downloads.)Students and the general public can use the data to monitor levels of light pollution around the world, as well as understand light pollution’s effects on energy consumption, plants, wildlife, human health and our ability to enjoy a starry night sky. Projects have compared Globe at Night data with ground-truthing using meters for energy audits as well as with data on birds and bats, population density, satellite data and trends over time. Globe at Night tackles grand challenges and everyday problems. It provides resources for formal and informal educators to engage learners of all ages. It has 9 years of experience in best practices for data management, design, collection, visualization, interpretation, etc. It has externally evaluated its program, workshops, lesson plans and accompanying kit to explore reasons for participation, skills developed, impact of experiences and perceived outcomes. Three recent papers (Birriel et al. 2014; Kyba et al. 2013; 2015) verify the

Role of lifestyle modifications for patients with laryngeal granuloma caused by gastro-esophageal reflux: comparison between conservative treatment and the surgical approach.

Science.gov (United States)

Kobayashi, Rika; Tsunoda, Koichi; Ueha, Rumi; Fujimaki, Yoko; Nito, Takaharu; Yamasoba, Tatsuya

2017-03-01

It is considered that a regimen combining pharmacologic management and lifestyle modifications is the most effective treatment for laryngeal granulomas caused by GER. This study compared the results of the combination therapy and surgery to determine the best treatment of laryngeal granuloma caused by gastro-esophageal reflux in 51 patients. Prospective study. In the conservative treatment group, the CR rate was 89.7% and recurrence rate was 2.6%, while the lesions remained in patients (7.7%). This study compared the CR and recurrence rates between conservative treatment and surgery for granuloma. The results showed that the laryngeal granuloma recurrence rate was significantly lower with the conservative treatment regimen compared with surgery (p = .0016).

Cross-border transfer of knowledge: Cultural lessons from project GLOBE

NARCIS (Netherlands)

Javidan, Mansour; Stahl, Günther K.; Brodbeck, Felix; Wilderom, Celeste P.M.

2005-01-01

Distant cross-border business is on the rise. It necessitates effective transfer of knowledge across geographic and cultural borders. In this article we present the key results from the GLOBE study of 62 cultures and apply them to a real-life case of a North European business school designing and

MSIs across the Globe: Laying the Foundation for Future Research

Science.gov (United States)

Hallmark, Tyler; Gasman, Marybeth

2018-01-01

In this paper, we explore the role that Minority Serving Institutions (MSIs) play in democratizing education in the USA and around the world, examining both the institutions and their larger context. We also put forth recommendations for reaching and empowering students attending MSIs and "students at the margins" across the globe.

Ethics and Corporal Punishment within the Schools across the Globe

Science.gov (United States)

Rajdev, Usha

2012-01-01

This paper contains cultural anthropological research on various discipline measures used within the classrooms in India, United Kingdom, China, Africa, and the United States. My recent visit to schools in India on study abroad programs prompted my desire to research across the globe different methods of classroom management discipline conducted…

Science and Math in the Library Media Center Using GLOBE.

Science.gov (United States)

Aquino, Teresa L.; Levine, Elissa R.

2003-01-01

Describes the Global Learning and Observations to Benefit the Environment (GLOBE) program which helps school library media specialists and science and math teachers bring earth science, math, information literacy, information technology, and student inquiry into the classroom. Discusses use of the Internet to create a global network to study the…

Fenced and Fragmented: Conservation Value of Managed Metapopulations

Science.gov (United States)

Miller, Susan M.; Harper, Cindy K.; Bloomer, Paulette; Hofmeyr, Jennifer; Funston, Paul J.

2015-01-01

Population fragmentation is threatening biodiversity worldwide. Species that once roamed vast areas are increasingly being conserved in small, isolated areas. Modern management approaches must adapt to ensure the continued survival and conservation value of these populations. In South Africa, a managed metapopulation approach has been adopted for several large carnivore species, all protected in isolated, relatively small, reserves that are fenced. As far as possible these approaches are based on natural metapopulation structures. In this network, over the past 25 years, African lions (Panthera leo) were reintroduced into 44 fenced reserves with little attention given to maintaining genetic diversity. To examine the situation, we investigated the current genetic provenance and diversity of these lions. We found that overall genetic diversity was similar to that in a large national park, and included a mixture of four different southern African evolutionarily significant units (ESUs). This mixing of ESUs, while not ideal, provides a unique opportunity to study the impact of mixing ESUs over the long term. We propose a strategic managed metapopulation plan to ensure the maintenance of genetic diversity and improve the long-term conservation value of these lions. This managed metapopulation approach could be applied to other species under similar ecological constraints around the globe. PMID:26699333

The Use of the Nelder-Mead Method in Determining Projection Parameters for Globe Photographs

Science.gov (United States)

Gede, M.

2009-04-01

A photo of a terrestrial or celestial globe can be handled as a map. The only hard issue is its projection: the so-called Tilted Perspective Projection which, if the optical axis of the photo intersects the globe's centre, is simplified to the Vertical Near-Side Perspective Projection. When georeferencing such a photo, the exact parameters of the projections are also needed. These parameters depend on the position of the viewpoint of the camera. Several hundreds of globe photos had to be georeferenced during the Virtual Globes Museum project, which made necessary to automatize the calculation of the projection parameters. The author developed a program for this task which uses the Nelder-Mead Method in order to find the optimum parameters when a set of control points are given as input. The Nelder-Mead method is a numerical algorithm for minimizing a function in a many-dimensional space. The function in the present application is the average error of the control points calculated from the actual values of parameters. The parameters are the geographical coordinates of the projection centre, the image coordinates of the same point, the rotation of the projection, the height of the perspective point and the scale of the photo (calculated in pixels/km). The program reads the Global Mappers Ground Control Point (.GCP) file format as input and creates projection description files (.PRJ) for the same software. The initial values of the geographical coordinates of the projection centre are calculated as the average of the control points, while the other parameters are set to experimental values which represent the most common circumstances of taking a globe photograph. The algorithm runs until the change of the parameters sinks below a pre-defined limit. The minimum search can be refined by using the previous result parameter set as new initial values. This paper introduces the calculation mechanism and examples of the usage. Other possible other usages of the method are

Collaterals 2016: Translating the collaterome around the globe.

Science.gov (United States)

Liebeskind, David S; Woolf, Graham W; Shuaib, Ashfaq

2017-06-01

Collaterals 2016 (third International Symposium on Collaterals to the Brain) was a multidisciplinary scientific conference focused on collateral circulation in acute ischemic stroke. Decisive challenges include generalizability of optimal triage and selection paradigms based on collateral status for definitive treatment of acute ischemic stroke, rapid dissemination of expert methods, and the urgent need to leverage networking opportunities for stroke science related to the hemodynamics of collaterals. The collaterome, or individual capacity to offset ischemia in the brain, and determination of a favorable collateral profile have become pivotal factors in consideration of the precision medicine of stroke decision-making. The conference convened over 50 invited faculty from around the world to connect on-site participants at a state-of-the-art facility with remote audiences in more than 22 countries and regions. The 2½-day program was structured into 40-min sessions devoted to key issues in translating the collaterome in acute stroke therapy across the globe. This unique forum of expertise emphasized the timely impact of collaterals on a monumental scale, encouraging maximal participation, rapid diffusion and added value of a diverse networking resource. The meeting format established a model geographical framework and innovative videoconferencing platform for future scientific conferences.

[The conservative treatment of placenta accreta. A clinical case report].

Science.gov (United States)

Artuso, A; Rocchi, B; Garbo, S; Baudino, G; Repetti, F

1993-09-01

The following description is a clinical case of placenta accreta and its conservative treatment. According to some authors, abnormal adhesion of the placenta depends on the alteration of the equilibrium between the trophoblastic tissue invasion and the reaction of the decidua. Consequently we have various degrees of penetration of the myometrium by chorionic villi into areas of deficit, sparse or absent decidua. Whatever the pathogenetic mechanism, the final clinical picture is slight to deep penetration of the trophoblastic tissue into the uterine wall. That causes absence of the normal plane of cleavage between placenta and maternal decidua, no spontaneous placental detachment during the third stage of labour and no possible manual removal. The patient, primigravida, was admitted at the 36th Week of gestation with PROM and physiologically delivered a neonate weighing 1820 g, after she spontaneously began labour. The newborn was admitted in the neonatal-pathology ward because it was premature although the Apgar score at 1-5 minutes after birth was 5-9. Placental ejection was awaited for 1 hour, then manual exploration of the uterine cavity was undertaken. The normal plane of cleavage between placental tissue and decidua was absent and therefore manual extraction of the placenta was impossible. Surgery was stopped and, after informed consensus was obtained from the patient, a conservative treatment was tried. After cutting the umbilical cord as short as possible and checking for vaginal bleeding, the patient was moved to obstetrics ward.(ABSTRACT TRUNCATED AT 250 WORDS)

Conservative surgery and radiotherapy in the treatment of breast cancer. Preliminary results of 148 patients

International Nuclear Information System (INIS)

Faria, S.L.; Chiminazzo Junior, H.; Koseki, N.; Oliveira Filho, J.A. de

1986-01-01

The combination of tumoral resection and radiotherapy with preservation of the breast is called conservative treatment of breast cancer. The literature considers this treatment a good option if used by an experient team and with appropriate equipment. This paper shows the results of 148 cases of breast cancer treated by this conservative approach at Centro de Oncologia Campinas. Follow-up varied from 3 to 87 months (mean 28) considered by the histological diagnosis. Overall actuarial survival of 5 years was 77% disease-free survival 55%. Twelve patients (8%) presented local relapse and 13 (9%) had distant metastases as the first therapeutic failure. Cosmetic results were considered good and fair in 89% of patients. These results are similar to others published in the literature (Author) [pt

Evaluation of Occupational Closed Globe Eye Injuries

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Berna Akova-Budak

2016-01-01

Full Text Available Aim: To evaluate closed glob injuries related to occupational accidents of patients who had official occupational accident records. Material and Method: The medical records of patients with ocular injuries who referred to Department of Ophthalmology or emergency of Uludag University, School of Medicine between January 2010 and December 2013 with official occupational accident report were retrospectively reviewed. The patients with closed globe injuries following trauma were included. Age, sex, the injured eye, the cause of the trauma, whether the precautions were taken or not by the patient, the damage due to trauma were recorded. Results: According to the official records, 108 patients referred to our clinic with closed globe injury related to occupational accident. One hundred twenty eyes of 108 patients ( 2 females, 106 males were evaluated. The mean age of the patients was 33±8.6 years. The most frequent cause of injury was foreign bodies on the ocular surface followed by blunt trauma. The mean age of the patients injured with foreign bodies was found to be significantly lower than the patients injured with blunt objects (p=0.039. Thirteen patients reported that they had used preventive equipment. Discussion: It is of utmost importance that the awareness of the workers should be raised and they should be educated about the use of preventive equipment to prevent the occupational eye injuries. The education of particularly the younger patients about the occupational injuries when they begin to work may decrease the rate of occupational accident related eye injuries.

Low back pain: conservative treatment with artificial shock absorbers.

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Wosk, J; Voloshin, A S

1985-03-01

A new method of conservative treatment for low back pain (LBP) was studied by follow-up investigation of 382 patients during the last five years. The attempt to reduce repetitive impulsive intervertebral impact in the troublesome S1-L5-4 area by significant improvement of the foot's attenuational capacity through artificial viscoelastic shock absorbing was prompted by the authors' work on decreased capability of LBP spines to attenuate axially propagated walking stresses. Viscoelastic shoe inserts were used in addition to light flexible shoes as artificial shock absorbing devices. Maximal amplitudes of bone oscillation during walking were reduced by about 40% by the viscoelastic inserts. Rapid and surprisingly significant improvement of pain syndrome and patient mobility occurred in about 80% of the patients. The accelerographic patterns recorded on a sacrum of patient with LBP were unusual for a healthy subject; they usually disappeared after treatment in LBP cases. Results suggested that poor walking impact attenuation was a true cause for prolonging intervertebral structures overstrain and consequent degeneration. It seemed logical that as spine damage could be explained primarily by prolonged impulsive overstrain, treatment must include viscoelastic inserts which increase foot shock absorbing capacity and help cushion the spine.

Diversity and Inclusion in Conservation: A Proposal for a Marine Diversity Network

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Nicola S. Smith

2017-08-01

Full Text Available Low diversity among scientists and practitioners is rampant in conservation. Currently, conservation professionals do not reflect the same diversity of perspectives and experiences of the world as the communities who bear the largest burden for implementing—or adverse consequences for failing to implement—conservation action. Acknowledging and describing the problem is important. But policies and programmes must also be put in place to correct it. Here, we highlight some measurable benefits of workforce diversity, and give an overview of some of the barriers to inclusion in marine conservation that help perpetuate low workforce diversity. Importantly, we underscore actions that both individuals and groups can take to alleviate such barriers. In particular, we describe the establishment of an online Marine Diversity Network, which conference participants proposed during a focus group meeting at the 4th International Marine Conservation Congress. The network will serve to bring together people from across the globe, from a variety of backgrounds, and from all career stages, to share knowledge, experiences and ideas, to provide and receive mentorship in marine conservation, and to forge new collaborations. Removing barriers to diverse participation requires coordinated, mindful actions by individuals and organizations. We hope that the proposed network and other actions presented in this paper find widespread support, and that they might serve both as inspiration and guide to other groups concerned with increasing diversity and inclusivity.

Efficacy of conservative treatment, without necrosectomy, for infected pancreatic necrosis: a systematic review and meta-analysis.

Science.gov (United States)

Mouli, Venigalla Pratap; Sreenivas, Vishnubhatla; Garg, Pramod Kumar

2013-02-01

Conservative treatment (intensive care, a combination of antimicrobial agents, and nutritional support, with or without drainage of the infected fluid) has recently been shown to be effective for patients with infected pancreatic necrosis (IPN), but the data from individual studies are not robust enough to recommend it as the standard of care. We performed a systematic review and meta-analysis of studies related to primary conservative management for IPN. We performed a literature search of MEDLINE/PubMed from January 1990 to March 2012 for studies of a priori protocols for primary conservative treatment, without necrosectomy, for consecutive patients with IPN. We analyzed data from 8 studies, comprising 324 patients with IPN who received primary conservative management. We then analyzed an additional 4 studies (comprising 157 patients) that reported the efficacy of percutaneous drainage in nonconsecutive patients with IPN. Outcome measures were the success of conservative management strategy, need for necrosectomy, and mortality. There was significant heterogeneity in results among the studies. Based on a random effects model, conservative management was successful for 64% of patients (95% confidence interval [CI], 51%-78%); mortality was 12% (95% CI, 6%-18%), and 26% of patients required necrosectomy or additional surgery for complications (95% CI, 15%-37%). A separate analysis of 4 studies that reported outcomes of nonconsecutive patients with IPN following percutaneous drainage had comparable results; 50% had successful outcomes (95% CI, 43%-58%), mortality was 18% (95% CI, 6%-30%), and 38% of patients required surgery (95% CI, 20%-56%). Conservative management without necrosectomy is a successful approach for 64% of patients with IPN. This approach has low mortality and prevents surgical necrosectomy. Copyright © 2013 AGA Institute. Published by Elsevier Inc. All rights reserved.

[Type 2 dens fracture in the elderly and therapy-linked mortality : Conservative or operative treatment].

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Stein, G; Meyer, C; Marlow, L; Christ, H; Müller, L P; Isenberg, J; Eysel, P; Schiffer, G; Faymonville, C

2017-02-01

Type II fractures of the odontoid process of the axis are the most common injury of the cervical spine in elderly patients. Only little evidence exists on whether elderly patients should be treated conservatively or surgically. The mortality and survival probability of 51 patients were determined in a retrospective study. The range of motion, pain and the neck disability index were clinically investigated. Of the 51 patients 37 were treated surgically and 14 conservatively. The conservatively treated group showed a higher mortality (64 % vs. 32 %). Kaplan-Meier analysis revealed a median survival of the conservatively treated group of 29 months, whereby during the first 3 months of treatment this group showed a higher survival probability and afterwards the surgically treated group showed a higher survival probability. The clinical examination of 20 patients revealed limited range of motion of the cervical spine. Additionally, moderate levels of pain and complaints were recorded using the neck disability index. Fractures of the odontoid process pose a far-reaching danger for elderly patients. A balanced assessment of the general condition should be carried out at the beginning of treatment of these patients. In the early phase following trauma no differences were found with respect to survival rates but for long-term survival the operatively treated group showed advantages; however, these advantages cannot be causally attributed to the choice of therapy.

Investigating the role of urban development in the conventional environmental Kuznets curve: evidence from the globe.

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Katircioglu, Setareh; Katircioglu, Salih; Kilinc, Ceyhun C

2018-03-19

We investigated the role of urbanization in the conventional environmental Kuznets curve (EKC) of the globe. The overall population and rural population were also considered for control purposes. Based on our findings, we suggest that the conventional EKC of the globe is not an inverted U-shape but becomes downward sloping when urban development is added and inverted U-shapes when the overall population and rural population volumes are added.

Tablet and Face-to-Face Hybrid Professional Development: Providing Earth Systems Science Educators Authentic Research Opportunities through The GLOBE Program at Purdue University

Science.gov (United States)

Wegner, K.; Branch, B. D.; Smith, S. C.

2013-12-01

The Global Learning and Observations to Benefit the Environment (GLOBE) program is a worldwide hands-on, primary and secondary school-based science and education program (www.globe.gov). GLOBE's vision promotes and supports students, teachers and scientists to collaborate on inquiry-based authentic science investigations of the environment and the Earth system working in close partnership with NASA, NOAA and NSF Earth System Science Projects (ESSP's) in study and research about the dynamics of Earth's environment. GLOBE Partners conduct face-to-face Professional Development in more than 110 countries, providing authentic scientific research experience in five investigation areas: atmosphere, earth as a system, hydrology, land cover, and soil. This presentation will provide a sample for a new framework of Professional Development that was implemented in July 2013 at Purdue University lead by Mr. Steven Smith who has tested GLOBE training materials for future training. The presentation will demonstrate how institutions can provide educators authentic scientific research opportunities through various components, including: - Carrying out authentic research investigations - Learning how to enter their authentic research data into the GLOBE database and visualize it on the GLOBE website - Learn how to access to NASA's Earth System Science resources via GLOBE's new online 'e-Training Program' - Exploring the connections of their soil protocol measurements and the history of the soil in their area through iPad soils app - LIDAR data exposure, Hydrology data exposure

A morphologically preserved multi-resolution TIN surface modeling and visualization method for virtual globes

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Zheng, Xianwei; Xiong, Hanjiang; Gong, Jianya; Yue, Linwei

2017-07-01

Virtual globes play an important role in representing three-dimensional models of the Earth. To extend the functioning of a virtual globe beyond that of a "geobrowser", the accuracy of the geospatial data in the processing and representation should be of special concern for the scientific analysis and evaluation. In this study, we propose a method for the processing of large-scale terrain data for virtual globe visualization and analysis. The proposed method aims to construct a morphologically preserved multi-resolution triangulated irregular network (TIN) pyramid for virtual globes to accurately represent the landscape surface and simultaneously satisfy the demands of applications at different scales. By introducing cartographic principles, the TIN model in each layer is controlled with a data quality standard to formulize its level of detail generation. A point-additive algorithm is used to iteratively construct the multi-resolution TIN pyramid. The extracted landscape features are also incorporated to constrain the TIN structure, thus preserving the basic morphological shapes of the terrain surface at different levels. During the iterative construction process, the TIN in each layer is seamlessly partitioned based on a virtual node structure, and tiled with a global quadtree structure. Finally, an adaptive tessellation approach is adopted to eliminate terrain cracks in the real-time out-of-core spherical terrain rendering. The experiments undertaken in this study confirmed that the proposed method performs well in multi-resolution terrain representation, and produces high-quality underlying data that satisfy the demands of scientific analysis and evaluation.

CONSERVATIVE TREATMENT VERSUS STEROID INJECTIONS IN THE MANAGEMENT OF UNICAMERAL BONE CYST

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Rajeev Kumar Roy

2017-05-01

Full Text Available BACKGROUND Unicameral Bone Cyst (UBC is described as a central metaphyseal cystic lesion of the bone with serum fluid content. Diagnosis is typically based on x-ray imaging features, age, localisation at proximal humerus and femur and the absence of symptoms until pathological fracture development. MATERIALS AND METHODS Eighteen patients with unicameral bone cysts were reviewed in Nalanda Medical College Hospital. Nine patients received serial steroid injections and the other nine patients were treated conservatively following fractures. In the steroid injection group, six cases were in the proximal femur and three in the proximal humerus. RESULTS The nine steroid injection patients showed radiological evidence of cyst healing within four months of treatment. Subsequently, all 9 patients showed a satisfactory radiological outcome after a year and complete resolution after 2 years. In the conservative group, all 9 cases were in the proximal humerus. Persistent cystic lesions were observed in all 9 patients and 2 was complicated by another fracture within 6 months. CONCLUSION Fractures through UBC in the upper extremity can be treated nonoperatively. However, steroid injection is an effective option to hasten healing and should be considered as a primary treatment of unicameral bone cyst.

Conservative Treatment of a Patient with Epidermolysis Bullosa Presenting as Bart Syndrome: A Case Report

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Samet Vasfi Kuvat

2010-01-01

Full Text Available We presented a case of a newborn male with aplasia cutis congenita on the lower limb. The case was treated with conservative method. As for the conservative treatment, daily hydrodebridement with 1/200 diluted povidone-iodine and serum physiologic was performed, followed by closure of the wound with a dexpanthenol + chlorhexidine + fusidic acid-impregnated sterile gauze bandage. the followup that occured after three weeks, the wound was completely epithelialized, but a hypopigmented scar remained in the limb.

ATRF Earns Three Green Globes, Exceeds NIH Building Standards | Poster

Science.gov (United States)

By Ashley DeVine, Staff Writer From project management and energy and water efficiency to emissions and the indoor environment, the Advanced Technology Research Facility (ATRF) was built with sustainability in mind, exceeding the National Institutes of Health’s (NIH’s) building standards and earning three Green Globes from the Green Building Initiative (GBI).

Do Interactive Globes and Games Help Students Learn Planetary Science?

Science.gov (United States)

Coba, Filis; Burgin, Stephen; De Paor, Declan; Georgen, Jennifer

2016-01-01

The popularity of animations and interactive visualizations in undergraduate science education might lead one to assume that these teaching aids enhance student learning. We tested this assumption for the case of the Google Earth virtual globe with a comparison of control and treatment student groups in a general education class of over 370 students at a large public university. Earth and Planetary Science course content was developed in two formats: using Keyhole Markup Language (KML) to create interactive tours in Google Earth (the treatment group) and Portable Document Format (PDF) for on-screen reading (the control group). The PDF documents contained identical text and images to the placemark balloons or "tour stops" in the Google Earth version. Some significant differences were noted between the two groups based on the immediate post-questionnaire with the KML students out-performing the PDF students, but not on the delayed measure. In a separate but related project, we undertake preliminary investigations into methods of teaching basic concepts in planetary mantle convection using numerical simulations. The goal of this project is to develop an interface with a two-dimensional finite element model that will allow students to vary parameters such as the temperatures assigned to the boundaries of the model domain, to help them actively explore important variables that control convection.

Effect of adjuvant systemic treatment on cosmetic outcome and late normal-tissue reactions after breast conservation

DEFF Research Database (Denmark)

Johansen, Jørgen; Overgaard, Jens; Overgaard, Marie

2007-01-01

To investigate whether adjuvant treatment with CMF or tamoxifen predisposes to an unfavorable cosmetic outcome or increased breast morbidity after radiotherapy in breast conservation. Data from 266 patients who entered a randomized breast conservation trial (DBCG-82TM protocol) was analyzed......-risk patients: premenopausal patients (n = 67) received eight cycles of CMF intravenously (600/40/600 mg per m(2)) every fourth week; postmenopausal patients (n = 27) received 30 mg of tamoxifen daily for one year. Clinical assessments included cosmetic outcome, breast fibrosis, skin telangiectasia....... In premenopausal patients, systemic treatment with CMF independently predicted a fair/poor cosmetic outcome, RR = 2.2 (95% CI 1.2-4.2), as well as increased skin telangiectasia, RR = 3.3 (1.4-8.2). There was no impact of tamoxifen treatment on cosmetic outcome in postmenopausal patients (p = 0.32). However...

Results of conservative, surgical treatment and rehabilitation of entrapment neuropathies in elderly patients in geriatric practice

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Jadwiga Główczewska

2017-03-01

Full Text Available Entrapment neuropahies of upper limbs can cause mainly nocturnal neuropathic pain and impaired manual dexterity. The most common entrapment neuropathy is carpal tunnel syndrome and ulnar groove syndrome - ulnar nerve entrapment at the elbow. Treatment of entrapment neuropathies is both analgetic therapy and physiotherapy. In the cases of conservative treatment inefficiencies surgical decompression of nerves is performed. Authors of this oublication present results of both conservative  and surgical of entrapment neuropathies in patients over 65 years old. Among the 17 patients with entraoment neuropathies 12 of them underwent surgical treatment. Achieved partial improvement in pain, mostly nocturnal and improving the quality of life and dexterity. In comparison, however, a group of younger patients who underwent surgery for the improvement was less spectacular, which may testify advancement and irreversibility of changes in older patients.

Conservative Treatment Seems the Best Choice in Adenocarcinoma In Situ of the Cervix Uteri.

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Baalbergen, Astrid; Molijn, Anco C; Quint, Wim G V; Smedts, Frank; Helmerhorst, Theo J M

2015-07-01

To study diagnostic and therapeutic strategies, outcomes, and follow-up in a large series of women with adenocarcinoma in situ (AIS) of the uterine cervix and investigate if human papillomavirus (HPV) typing among women with negative cytology reports would have helped with early AIS detection. Records of 132 AIS cases diagnosed between 1989 and 2012 were retrieved. Clinical and pathological data were reviewed and analyzed. Mean age at diagnosis was 37 years. Seventy-two percent (n = 95) of all patients were asymptomatic; diagnosis was established using cytology and biopsy. Primary treatment for 124 patents was cold knife cone or loop electrosurgical excision procedure (LEEP). Positive margins were found in 18% of those women treated with CKC versus 40% in those treated with LEEP. The mean follow-up time was 62 months (range, 2-217 months; median, 46 months). Three recurrences were found after conservative treatment in 86 patients. High-risk HPV (hrHPV) positivity was detected in 115 (96%) of 120 patients, with HPV-18 being the most commonly occurring subtype (51%). There is a small risk of relapse after conservative therapy with cold knife cone or LEEP when resection margins are negative in women with AIS. Patients should be given the options of hysterectomy or conservative therapy with strict follow-up.

Identifying Important Atlantic Areas for the conservation of Balearic shearwaters: Spatial overlap with conservation areas

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Pérez-Roda, Amparo; Delord, Karine; Boué, Amélie; Arcos, José Manuel; García, David; Micol, Thierry; Weimerskirch, Henri; Pinaud, David; Louzao, Maite

2017-07-01

Marine protected areas (MPAs) are considered one of the main tools in both fisheries and conservation management to protect threatened species and their habitats around the globe. However, MPAs are underrepresented in marine environments compared to terrestrial environments. Within this context, we studied the Atlantic non-breeding distribution of the southern population of Balearic shearwaters (Puffinus mauretanicus) breeding in Eivissa during the 2011-2012 period based on global location sensing (GLS) devices. Our objectives were (1) to identify overall Important Atlantic Areas (IAAs) from a southern population, (2) to describe spatio-temporal patterns of oceanographic habitat use, and (3) to assess whether existing conservation areas (Natura 2000 sites and marine Important Bird Areas (IBAs)) cover the main IAAs of Balearic shearwaters. Our results highlighted that the Atlantic staging (from June to October in 2011) dynamic of the southern population was driven by individual segregation at both spatial and temporal scales. Individuals ranged in the North-East Atlantic over four main IAAs (Bay of Biscay: BoB, Western Iberian shelf: WIS, Gulf of Cadiz: GoC, West of Morocco: WoM). While most individuals spent more time on the WIS or in the GoC, a small number of birds visited IAAs at the extremes of their Atlantic distribution range (i.e., BoB and WoM). The chronology of the arrivals to the IAAs showed a latitudinal gradient with northern areas reached earlier during the Atlantic staging. The IAAs coincided with the most productive areas (higher chlorophyll a values) in the NE Atlantic between July and October. The spatial overlap between IAAs and conservation areas was higher for Natura 2000 sites than marine IBAs (areas with and without legal protection, respectively). Concerning the use of these areas, a slightly higher proportion of estimated positions fell within marine IBAs compared to designated Natura 2000 sites, with Spanish and Portuguese conservation

Invasive bladder cancer: treatment strategies using transurethral surgery, chemotherapy and radiation therapy with selection for bladder conservation

International Nuclear Information System (INIS)

Shipley, William U.; Zietman, Anthony L.; Kaufman, Donald S.; Althausen, Alex F.; Heney, Niall M.

1997-01-01

Purpose: Combined modality therapy has become the standard oncologic approach to achieve organ preservation in many malignancies. Methods and Materials: Although radical cystectomy has been considered as standard treatment for invasive bladder carcinoma in the United States, good results have been recently reported from several centers using multimodality treatment, particularly in patients with clinical T2 and T3a disease who do not have a ureter obstructed by tumor. Results: The components of the combined treatment are usually transurethral resection of the bladder tumor (TURBT) followed by concurrent chemotherapy and radiation therapy. Following an induction course of therapy a histologic response is evaluated by cystoscopy and rebiopsy. Clinical 'complete responders' (tumor site rebiopsy negative and urine cytology with no tumor cells present) continue with a consolidation course of concurrent chemotherapy and radiation. Those patients not achieving a clinical complete response are recommended to have an immediate cystectomy. Individually the local monotherapies of radiation, TURBT, or multidrug chemotherapy each achieve a local control rate of the primary tumor of from 20 to 40%. When these are combined, clinical complete response rates of from 65 to 80% can be achieved. Seventy-five to 85% of the clinical complete responders will remain with bladders free of recurrence of an invasive tumor. Conclusions: Bladder conservation trials using combined modality treatment approaches with selection for organ conservation by response of the tumor to initial treatment report overall 5-year survival rates of approximately 50%, and a 40-45% 5-year survival rate with the bladder intact. These modern multimodality bladder conservation approaches offer survival rates similar to radical cystectomy for patients of similar clinical stage and age. Bladder-conserving therapy should be offered to patients with invasive bladder carcinoma as a realistic alternative to radical

Phenotyping, Genotyping, and Selections within Italian Local Landraces of Romanesco Globe Artichoke

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Paola Crinò

2017-03-01

Full Text Available Ten Italian globe artichoke clones belonging to the Romanesco typology were characterized in the western coastal area of Italy (Cerveteri, Rome, using a combination of morphological (UPOV descriptors, biochemical (HPLC analysis, and molecular (AFLP, ISSR, and SSR markers traits. Significant differences among clones were found for many of the quantitative and qualitative morphological traits. Multivariate analyses (Principal Component Analysis showed that, of the 47 morphological descriptors assessed, four (i.e., plant height, central flower-head weight, earliness, and total flower-head weight presented a clear grouping of the clones. Biochemical analyses showed that the clones significantly differed in the polyphenolic profiles of the flower-head, with the suggestion that some of these, such as S2, S3, S5, and S18, are more suitable for the fresh market. The clones, clustered by a UPGMA dendrogram based on 393 polymorphic AFLP and ISSR loci, showed that the clones were genetically separated from each other. This highlights the importance of characterizing, evaluating, and conserving autochthonous germplasm for future plant breeding activities. Overall, these studies resulted in the identification of two new clones, selected on the basis of flower-head morphology and earliness. These clones, named Michelangelo and Raffaello, are registered on the Italian National Register of Varieties (DM n. 6135, 3/29/2013 G.U. 91, 18 April 2013.

Linking diversity and distribution to understand biodiversity gradients and inform conservation assessments

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Fabricio Villalobos

2014-03-01

Full Text Available Broad-scale patterns of species richness result from differential coexistence among species in distinct regions of the globe, determined by the species’ ranges and their properties such as size, shape and location. Thus, species richness and ranges are inherently linked. These two biodiversity features also yield primary information for conservation assessments. However, species richness and range size have been usually studied separately and no formal analytical link has been established. In my PhD thesis, I applied and extended a recently developed conceptual and methodological framework to study geographical association among species and similarity among sites. This range–diversity framework, along with stochastic simulation modelling, allowed me to jointly evaluate the relationship between diversity and distribution, to infer potential processes underlying composite patterns of phyllostomid bats, and to use this approach to inform conservation assessments for the Mexican avifauna. I highlight the need to explore composite patterns for understanding biodiversity patterns and show how combining diversity and distributional data can help describe complex biogeographical patterns, providing a transparent and explicit application for initial conservation assessments.

Conservative treatment and rehabilitation of shoulder problems; Konservative Therapie und Rehabilitation von Schulterbeschwerden

Energy Technology Data Exchange (ETDEWEB)

Paternostro-Sluga, T.; Zoech, C. [Klinik fuer Physikalische Medizin und Rehabilitation, Allgemeines Krankenhaus der Medizinischen Universitaet Wien (Austria)

2004-06-01

The shoulder joint has an important influence on arm- and handfunction. Therefore, activities of daily living, working and leisure time can be negatively influenced by diseases of the shoulder joint. Problems of the shoulder joint can be induced by muscular dysbalance and poor body posture. There is a strong relationship between shoulder function and body posture. Conservative treatment and rehabilitation of the shoulder joint aims at improving the local dysfunction of the shoulder joint as well as at improving function and social participation. Antiinflammatory and pain medication, exercise, occupational, electro-, ultrasound and shock wave therapy, massage, thermotherapy and pulsed electromagnetic fields are used as conservative treatments. Exercise therapy aims at improving muscular performance, joint mobility and body posture. Occupational therapy aims at improving functional movements for daily living and work. Electrotherapy is primarily used to relieve pain. Shock wave and ultrasound therapy proved to be an effective treatment for patients with calcific tendinitis. The subacromial impingement syndrome can be effectively treated by conservative therapy. (orig.) [German] Aufgrund der zentralen Rolle des Schultergelenks fuer die Arm- und Handfunktion koennen Erkrankungen des Schultergelenks zu einer erheblichen Beeintraechtigung in Alltag, Beruf und Freizeit fuehren. Muskulaere Dysbalancen und Fehlhaltungen sind haeufige Ursachen fuer Schulterbeschwerden. Es besteht eine enge Beziehung zwischen Schulterfunktion und Koerperhaltung. Therapieziele in der konservativen Behandlung und Rehabilitation sind neben der Verbesserung der lokalen Situation das Wiedererlangen der Funktion und sozialen Partizipation. Zu den konservativen Therapiemassnahmen zaehlen medikamentoese, Bewegungs-, Ergo-, Elektro-, Ultraschall- und Stosswellentherapie, Massage, Thermo- und Magnetfeldtherapie. Muskulaere Dysbalancen und Fehlhaltungen sind durch bewegungstherapeutische Massnahmen gut

Conservative treatment of idiopathic spontaneous pneumoperitoneum in a bedridden patient: a case report.

Science.gov (United States)

Tanaka, Ryo; Kameyama, Hitoshi; Nagahashi, Masayuki; Kanda, Tatsuo; Ichikawa, Hiroshi; Hanyu, Takaaki; Ishikawa, Takashi; Kobayashi, Takashi; Sakata, Jun; Kosugi, Shin-Ichi; Wakai, Toshifumi

2015-01-01

Idiopathic spontaneous pneumoperitoneum is a rare condition that is characterized by intraperitoneal gas for which no clear etiology has been identified. We report here a case of idiopathic spontaneous pneumoperitoneum, which was successfully managed by conservative treatment. A 77-year-old woman who was bedridden with speech disability as a sequela of brain hemorrhage presented at our hospital with a 1-day history of abdominal distention. On physical examination, she had stable vital signs and slight epigastric tenderness on deep palpation without any other signs of peritonitis. A chest radiograph and computed tomography showed that a large amount of free gas extended into the upper abdominal cavity. Esophagogastroduodenoscopy revealed no perforation of the upper gastrointestinal tract. The patient was diagnosed with idiopathic spontaneous pneumoperitoneum, and conservative treatment was selected. The abdominal distension rapidly disappeared, and the patient resumed oral intake on the 5th hospital day without deterioration of symptoms. Knowledge of this rare disease and accurate diagnosis with findings of clinical imaging might contribute towards refraining from unnecessary laparotomy.

Subclinical ductal carcinoma in situ of the breast: treatment with conservative surgery and radiotherapy.

Science.gov (United States)

Amichetti, M; Caffo, O; Richetti, A; Zini, G; Rigon, A; Antonello, M; Roncadin, M; Coghetto, F; Valdagni, R; Fasan, S; Maluta, S; Di Marco, A; Neri, S; Vidali, C; Panizzoni, G; Aristei, C

1999-01-01

In spite of the fact that ductal carcinoma in situ (DCIS) of the breast is a frequently encountered clinical problem, there is no consensus about the optimal treatment of clinically occult (i.e., mammographic presentation only) DCIS. Interest in breast conservation therapy has recently increased. Few data are available in Italy on the conservative treatment with surgery and adjuvant postoperative radiotherapy. A retrospective multi-institutional study was performed in 15 Radiation Oncology Departments in northern Italy involving 112 women with subclinical DCIS of the breast treated between 1982 and 1993. Age of the patients ranged between 32 and 72 years (median, 50 years). All of them underwent conservative surgery: quadrantectomy in 89, tumorectomy in 11, and wide excision in 12 cases. The most common histologic subtype was comedocarcinoma (37%). The median pathologic size was 10 mm (range 1 to 55 mm). Axillary dissection was performed in 83 cases: all the patients were node negative. All the patients received adjunctive radiation therapy with 60Co units (77%) or 6 MV linear accelerators (23%) for a median total dose to the entire breast of 50 Gy (mean, 49.48 Gy; range, 45-60 Gy). Seventy-six cases (68%) received a boost to the tumor bed at a dose of 8-20 Gy (median 10 Gy) for a minimum tumor dose of 58 Gy. At a median follow-up of 66 months, 8 local recurrences were observed, 4 intraductal and 4 invasive. All recurrent patients had a salvage mastectomy and are alive and free of disease at this writing. The 10-year actuarial overall, cause-specific, and recurrence-free survival was of 98.8%, 100%, and 91%, respectively. The retrospective multicentric study, with a local control rate of more than 90% at 10 years with 100% cause-specific survival, showed that conservative surgery and adjuvant radiation therapy is a safe and efficacious treatment for patients with occult, non-palpable DCIS.

The Pale Blue Dot: Utilizing Real World Globes in High School and Undergraduate Oceanography Classrooms

Science.gov (United States)

Rogers, D. B.

2017-12-01

Geoscience classrooms have benefitted greatly from the use of interactive, dry-erasable globes to supplement instruction on topics that require three-dimensional visualization, such as seismic wave propagation and the large-scale movements of tectonic plates. Indeed, research by Bamford (2013) demonstrates that using three-dimensional visualization to illustrate complex processes enhances student comprehension. While some geoscience courses tend to bake-in lessons on visualization, other disciplines of earth science that require three-dimensional visualization, such as oceanography, tend to rely on students' prior spatial abilities. In addition to spatial intelligence, education on the three-dimensional structure of the ocean requires knowledge of the external processes govern the behavior of the ocean, as well as the vertical and lateral distribution of water properties around the globe. Presented here are two oceanographic activities that utilize RealWorldGlobes' dry-erase globes to supplement traditional oceanography lessons on thermohaline and surface ocean circulation. While simultaneously promoting basic plotting techniques, mathematical calculations, and unit conversions, these activities touch on the processes that govern global ocean circulation, the principles of radiocarbon dating, and the various patterns exhibited by surface ocean currents. These activities challenge students to recognize inherent patterns within their data and synthesize explanations for their occurrence. Spatial visualization and critical thinking are integral to any geoscience education, and the combination of these abilities with engaging hands-on activities has the potential to greatly enhance oceanography education in both secondary and postsecondary settings

Sustainable development and CERN’s role: Panel discussion at the Globe

CERN Multimedia

CERN Bulletin

2012-01-01

On Thursday 21 June, on the occasion of the UN Rio+20 Conference on Sustainable Development, some ambitious ecological projects involving CERN and its technologies will be presented in an afternoon of lectures and discussions in the Globe. The event is an opportunity for people at CERN to discuss the Organization’s green credentials and their ecological impact on life in the local area.   “The Globe was seen as a metaphor for the planet and a symbol of sustainable development when it was known as the ‘Palace of Equilibrium’ at Expo02 in Switzerland. Now here at CERN, it is the perfect place to host a debate on the role of technology and innovation in this area," enthuses Bernard Pellequer, who is in charge of event planning for the venue. On the afternoon of 21 June, speakers will present several ambitious projects, such as the eco-neighbourhood “Les Vergers”, the Vernes lake in ...

Laparoscopic conservative treatment of colo-vesical fistula: a new surgical approach

Directory of Open Access Journals (Sweden)

Cochetti Giovanni

2013-09-01

Full Text Available Introduction The standard treatment of colo-vesical fistula is the exeresis of fistula, suture of bladder wall, colic resection with or without temporary colostomy. Usually the approach is open because conversion rates and morbidity are lower than laparoscopy. The aim of video is to show the steps of a new mini-invasive approach of colo-vesical fistula without colic resection. Materials and Methods A 69 years old male underwent laparoscopic conservative treatment of colo-vesical fistula due to endoscopic polipectomy in sigmoid diverticulum. 12 mm trocar for the camera was placed at the umbilicus, two 10 mm trocars were placed along bisiliac line and 5 mm port was placed along left emiclavear line; Trendelenburg position was 20°. The fistulous loop was carefully isolated, clipped with Hem-o-lock® clips and removed. Since diverticular disease appeared slight and no inflammation signs were evident, colon resection was not performed. We sutured and sinked the sigmoid wall; after curettage of the fistula site, the bladder wall was sutured. Fat tissue was placed between sigmoid and bladder wall to reduce the risk of fistula recurrence. Results Operative time, estimated blood loss, catheterization time, time to flatus and hospital stay were respectively 210 minutes, 300 mL, 10 days, 48 h and 8 days. The histological examination showed colonic inflammatory and necrotic tissue. No complications or fistula recurrence occurred at 54 months follow-up. Conclusions The laparoscopic conservative treatment of colo-vesical fistula is a safe and feasible technique, in particular when the diverticular disease is limited and the fistula is not due to diverticulitis.

PREDICTING PROGNOSTIC VALUE OF OCULAR TRAUMA SCORE (OTS IN AN OPEN GLOBE INJURY IN TERTIARY EYE CARE HOSPITAL

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Rahul

2015-10-01

Full Text Available AIM : To evaluate the prognostic value of OTS in open globe injuries. MATERIAL METHOD : Retrospective analysis of 77 eyes with open globe injuries was done from 01/07/2013 to 31/12/2014. Patients were assigned raw score sum based on initial V/A, and ocular findings then classified into 5 categories for predicting final visual outcome based on ocular Trauma score (OTS. RESULT : We estimated final V/A in 77 cases of open globe injuries (64.93% had raw sc ore between 65.91 (category 3, 4 Six months after the injury, 42.85% patients of categories 1 (raw score 0 - 44 achieved V/A of PL/HM as compared to 17% in OTS study. 16 patients with raw compared to OTS study. We reported comparable visual outcome with OT S study except in category 1 & 2. CONCLUSION: OTS score is valuable in triage, patient counseling and decision making for the management of ocular trauma. We recommend that OTS should be used routinely for open globe injuries as it is a simple guide

Physiotherapy and Rehabilitation Interventions in the Conservative Treatment of Chondrocalcinosis: A Case Report

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Bihter Akınoğlu

2017-09-01

Full Text Available Chondrocalcinosis is defined as the accumulation of crystals of calcium pyrophosphate in the hyaline cartilage and fibrous tissue. A 24 years old tennis player referred to our clinic with chondrocalcinosis diagnosis, for conservative treatment. On admission, she had pain and difficulty in walking, stair climbing and sitting up, as well as weakness in front thigh muscles. High voltage galvanic stimulation, isokinetic strength training and home exercises were applied two days a week for six weeks. Following the treatment, there were significant improvements in her daily life activities and quadriceps muscle strength.

Trial-by-fire transformation: an interview with Globe Metallurgical's Arden C. Sims. Interview by Bruce Rayner.

Science.gov (United States)

Sims, A C

1992-01-01

Globe Metallurgical Inc., a $115 million supplier of specialty metals, is best known as the first small company to win the Baldrige Award in 1988. But there is much more to this gutsy little company than total quality. During the 1980s, Globe transformed itself from a rust-belt has-been on the verge of bankruptcy into a high-technology, high-quality industry leader. Along the way, the company went private in a management-led leveraged buyout, embraced flexible work teams, adopted a high-value-added, niche marketing strategy, and took its business global. Leading the way in Globe's reinvention was Chief Executive Arden C. Sims, the slow-talking son of a West Virginian coal miner. When he joined the company in 1984, Sims had no experience in the new managerial techniques. He was a product of the old school of management: cut costs and trim operations to regain competitiveness. But he soon discovered that old-style management was not enough to battle offshore competitors, an unproductive work force, rising costs, and outdated production technology. He was forced to go looking for new ideas and practices. In a succession of learning experiences, Sims attended a seminar on total quality in 1985, paving the way for the company's quality program; he discovered the power of flexible work teams when management was forced to run the furnaces during a year-long strike; he organized an LBO, allowing him to change the work order even more dramatically; and he took the company global and into highly profitable niche markets by severing a long-standing relationship with Globe's sales and marketing representative. As a result of these and other changes, Globe leads the specialty metals industry in virtually all performance measures.

Outcomes of conservative treatment of giant omphaloceles with dissodic 2% aqueous eosin: 15 years′ experience

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B. D. Kouame

2014-01-01

Full Text Available Background: The surgical management of giant omphalocele is a surgical challenge with high mortality and morbidity in our country due to the absence of neonatal resuscitation. This study evaluates conservative management of giant omphalocele with dissodic 2% aqueous eosin. Materials and Methods: In the period from January 1997 to December 2012, giant omphaloceles were treated with dissodic 2% aqueous eosin. The procedure consisted of twice a day application of dissodic 2% aqueous eosin (sterile solution for topical application on the omphalocele sac. The procedure was taught to the mother to continue at home with an outpatient follow-up to assess epithelialization. We studied the duration of the hospital stay, the learning curve of the procedure by the mother, the complications, the duration and the percentage of complete epithelialization and the mortality. Results: A total of 173 giant omphaloceles had a conservative treatment with dissodic 2% aqueous eosin. The average hospital stay was 21 ± 6 days. The learning curve by the mother of the procedure was 10 ± 3 days. Complications of treatment were intestinal functional occlusion 22% and omphalocele sac infection 18%. The complete epithelialization of the omphaloceles sac after application of dissodic 2% aqueous eosin was 68.5%. Mortality was observed in 25.5%. Conclusion: Conservative treatment of giant omphaloceles by dissodic 2% aqueous eosin is a simple, efficient and a good alternative to surgery. The mother can easily learn its procedure which reduces the duration of hospital stay.

The Globe: Exhibitions and Events

CERN Multimedia

2007-01-01

Globe of Science and Innovation Route de Meyrin, 1211 Geneva Conference Nano materials: small dimensions, big opportunities Thursday 22 November at 8.00 p.m. Christoph Renner, Professor of Physics and Deputy Director of MaNEP*Information technologies have developed at an incredible pace over the past sixty years. Mobile phones, MP3 players and other modern gizmos are infinitely more powerful than the first computers, which took up whole rooms! The main driving force behind this evolutionary process has been the boom in the miniaturisation of electronic components. The latest technological innovations have led to a new range of tools being developed, allowing matter to be visualised, manipulated and characterised at the smallest possible scales, molecule by molecule and even atom by atom. At these scales, the behaviour of matter is altered as the conventional properties of mass are gradually taken over by quantum effects with which we are quite unfamiliar in our everyday li...

Sustainability debate at the Globe

CERN Multimedia

Joannah Caborn Wengler

2012-01-01

Eco-neighbourhoods, solar panels, recycled heat: these were just some of the innovative ecological projects presented at the panel discussion organised by the Commune of Meyrin at the Globe on Thursday 21 June. CERN is closely involved with several of the projects.   CERN has an important role to play in sustainable development, and in Meyrin it has an excellent local partner. This was perhaps the key message, from CERN’s point of view, to come out of Thursday’s event. It particularly highlighted the proposed plan to use part of the “waste” heat going to the cooling towers at Point 1 to contribute to heating Meyrin’s new ecological housing project, Les Vergers. Some of CERN’s other high-profile contributions to sustainable development, such as the solar panels using CERN vacuum technology on the airport roof, were also presented. The video below presents some of the main ideas and actors in the CERN-Meyrin partnership. Please note that t...

Literatur zu Gast im Globe

CERN Multimedia

2006-01-01

Der deutsche Schriftsteller Thomas LEHR liest am 23. März 2006 aus seinem Roman '42', einem philosophischen Abenteuerroman über die Suche nach der Zeit, erzählt in einer funkelnden und souveränen Sprache. Eine Welt von vernichtender Schönheit und bizarren Schrecken wartet auf eine Besuchergruppe, die in der Nähe von Genf die unterirdischen Anlagen des Forschungszentrums für Teilchenphysik CERN besichtigt. Als sie um 12:47:42 wieder ans Tageslicht tritt, scheint ganz Europa in einen Dornröschenschlaf gefallen. Allein die 70 Besucher können sich noch bewegen. Monate und Jahre verharrt die Welt wie in einer riesigen dreidimensionalen Fotografie, bis ein wiederum schockierendes Ereignis die 'Chronifizierten' aus ihren physikalischen Spekulationen und seltsamen Lebensformen reisst. Zu dieser literarischen Veranstaltung im 'Globe of Science and Innovation' laden gemeinsam das Generalkonsulat der Bundesrepublik Deutschland in Genf und CERN ein. Vor Beginn der Lesung wird eine Führung in deutscher Sprac...

Live broadcast from the Globe

CERN Multimedia

La tête au carréTuesday, 17 June 2008 between 2.00 and 3.00 p.m.“La tête au carré”, a France Inter radio programme devoted to science, will set up its sound booth at CERN for a special broadcast on the LHC.The journalist Mathieu Vidard will interview the following guests: - Pierre Van Hove, an experimental physicist working on CMS. He is a CNRS research scientist from the Institut Hubert Curien in Strasbourg, France.- Abdelhak Djouadi is a theoretical physicist. He is a research director at the CNRS’s Laboratoire de physique théorique at Orsay, France and holder of the CNRS silver medal.- Magali Gruwe, one of the engineers in charge of LHC operations at CERN.» To take part in this live broadcast, which is open to the public, come to the Globe at 1:30 p.m. The number of places is limited.» No specialist knowledge required.» See the programme's homepage

2008 events in the Globe

CERN Multimedia

2008-01-01

Globe of Science and Innovation 1st floor - Route de Meyrin, 1211 Geneva Interactive exhibition Superconductivity—magical attraction From Tuesday, 28 October, to Saturday, 13 December 2008 Tuesdays and Wednesdays from 2.00 p.m. to 5.30 p.m. Saturdays from 9 a.m. to 5.00 p.m. The phenomenon of superconductivity was discovered a century ago. The first step was taken in 1907 when helium was liquefied for the first time. The capability to cool materials down to temperatures of -269°C (4.2K), made it possible to study the new phenomenon of superconductivity. The properties of this amazing discovery are already being used in a variety of applications in such areas as medical imaging, energy transportation, storage, magnetic levitation and transportation, and electronics. Come and find out how superconductivity has been used for the magnets of CERN’s new accelerator, and test the feeling of levitation for yourself! Free entry - No specialist knowledge required. Fête de ...

2008 events in the Globe

CERN Multimedia

2008-01-01

Globe of Science and Innovation 1st floor - Route de Meyrin, 1211 Geneva Interactive exhibitionSuperconductivity—magical attraction From Tuesday, 28 October, to Saturday, 13 December 2008 Tuesdays and Wednesdays from 2.00 p.m. to 5.30 p.m. Saturdays from 9 a.m. to 5.00 p.m. The phenomenon of superconductivity was discovered a century ago. The first step was taken in 1907 when helium was liquefied for the first time. The capability to cool materials down to temperatures of -269°C (4.2K), made it possible to study the new phenomenon of superconductivity. The properties of this amazing discovery are already being used in a variety of applications in such areas as medical imaging, energy transportation, storage, magnetic levitation and transportation, and electronics. Come and find out how superconductivity has been used for the magnets of CERN’s new accelerator, and test the feeling of levitation for yourself! Free entry - No specialist knowledge required. In mathema...

The Globe: Exhibitions and Events

CERN Multimedia

2007-01-01

The LHC, accelerator of scienceCERN is soon to commission the world’s most powerful accelerator, the LHC (Large Hadron Collider), which will provide us with new insights into the Universe and how it evolved. This series of lectures is all about understanding the scientific and technological challenges of this phenomenal project and assessing its innovations through their everyday applications. Come and take a sneak preview of the LHC! Thursday 29 November, 8:00 p.m. Share: leading-edge technology at the service of society Jean-Marie Le Goff, physicist and head of technology transfer at CERN The technologies used by the LHC are already finding applications in other scientific fields, such as medicine, climatology, metrology and computer science. Through its ground-breaking technologies, particle physics benefits society as a whole.>>>> Lectures are free and require no specialist knowledge. In French.>>> By reservation only: tel. +41 (0)22 767 76 76 http://globe.web.cern.c...

Restricted-range fishes and the conservation of Brazilian freshwaters.

Directory of Open Access Journals (Sweden)

Cristiano Nogueira

Full Text Available BACKGROUND: Freshwaters are the most threatened ecosystems on earth. Although recent assessments provide data on global priority regions for freshwater conservation, local scale priorities remain unknown. Refining the scale of global biodiversity assessments (both at terrestrial and freshwater realms and translating these into conservation priorities on the ground remains a major challenge to biodiversity science, and depends directly on species occurrence data of high taxonomic and geographic resolution. Brazil harbors the richest freshwater ichthyofauna in the world, but knowledge on endemic areas and conservation in Brazilian rivers is still scarce. METHODOLOGY/PRINCIPAL FINDINGS: Using data on environmental threats and revised species distribution data we detect and delineate 540 small watershed areas harboring 819 restricted-range fishes in Brazil. Many of these areas are already highly threatened, as 159 (29% watersheds have lost more than 70% of their original vegetation cover, and only 141 (26% show significant overlap with formally protected areas or indigenous lands. We detected 220 (40% critical watersheds overlapping hydroelectric dams or showing both poor formal protection and widespread habitat loss; these sites harbor 344 endemic fish species that may face extinction if no conservation action is in place in the near future. CONCLUSIONS/SIGNIFICANCE: We provide the first analysis of site-scale conservation priorities in the richest freshwater ecosystems of the globe. Our results corroborate the hypothesis that freshwater biodiversity has been neglected in former conservation assessments. The study provides a simple and straightforward method for detecting freshwater priority areas based on endemism and threat, and represents a starting point for integrating freshwater and terrestrial conservation in representative and biogeographically consistent site-scale conservation strategies, that may be scaled-up following naturally linked

Complete Remodeling After Conservative Treatment of a Severely Angulated Odontoid Fracture in a Patient With Osteogenesis Imperfecta: A Case Report.

Science.gov (United States)

Colo, Dino; Schlösser, Tom P C; Oostenbroek, Hubert J; Castelein, René M

2015-09-15

Case report. This is the first case report describing successful healing and remodeling of a traumatic odontoid fracture that was dislocated and severely angulated in a patient with osteogenesis imperfecta who was treated conservatively. Osteogenesis imperfecta (OI) is a rare genetic disorder resulting in a low bone mass and bone fragility, predisposing these patients to fractures that often occur at a young age. Although any bone in the body may be involved, odontoid fractures are uncommon in this population. Because of a very high fusion rate, conservative management is accepted as a safe and efficient treatment of fractures of the odontoid in children. Several authors, however, recommend surgical treatment of patients who have failure of conservative treatment and have severe angulation or displacement of the odontoid. A 5-year-old female, diagnosed with OI type I, presented with neck pain without any neurological deficits after falling out of a rocking chair backward, with her head landing first on the ground. Computed tomography confirmed a type III odontoid fracture without dislocation and she was initially treated with a rigid cervical orthosis. At 1 and 2 months of follow-up, progressive severe angulation of the odontoid was observed but conservative treatment was maintained as the space available for the spinal cord was sufficient and also considering the patient's history of OI. Eight months postinjury, she had no clinical symptoms and there was osseous healing of the fracture with remodeling of the odontoid to normal morphology. Even in patients with OI, severely angulated odontoid fractures might have the capacity for osseous healing and complete remodeling under conservative treatment. 5.

Critical evaluation of the use of imaging techniques in the conservative treatment of breast cancer

International Nuclear Information System (INIS)

Pena, F.; Vega, C.; Pastrana, M.; Gonzalez, C.; Ramos, L.

1996-01-01

To establish the need for a sequential radiological study to contribute, together with other specialists in the management of these patients, to achieve the best possible results with this type of treatment: rates of survival comparable to those obtained with mastectomy and the highest possible percentages of breast preservation with satisfactory cosmetic results. Studies of 200 patients who underwent conservative treatment for breast cancer at Clinica Puerta de Hierro in Madrid over the past five years.We assess the utility of the different imaging methods and their application in each specific case. An update of the literature is also carried out. Radiology plays a major role in the management of patients who undergo conservative treatment for breast cancer. We demonstrate the need to carry out, in the first place, preoperative radiological studies to aid in the proper selection of patients and, secondly, examination of the resected tissue and postoperative mammography to ensure that the surgical resection was performed correctly. Finally, follow-up studies be carried out to detect tumor recurrence as early as possible. (Author) 82 refs

[Lateral epicondylitis: conservative - operative].

Science.gov (United States)

Altintas, Burak; Greiner, Stefan

2016-10-01

Lateral epicondylitis is a common disease of the common extensor origin at the lateral humerus. Despite its common self-limitation it can lead to chronic therapy-resistant pain with remarkable functional disability of the affected arm. Different conservative and operative treatment options of lateral epicondylitis are described and compared regarding benefits and risks. Additionally, recent surgical techniques and their complications are mentioned. Based on the current literature, it is shown which treatment option can be recommended. This review was based on the literature analysis in PubMed regarding "conservative and operative therapy of lateral epicondylitis" as well as the clinical experience of the authors. Conservative treatment is the primary choice for the treatment of lateral epicondylitis if concomitant pathologies such as instability among others can be excluded. It should include strengthening against resistance with eccentric stretching of the extensor group. In persistent cases, operative treatment is warranted. Resection of the pathologic tissue at the extensor origin with debridement and refixation of the healthy tendinous tissue yields good results. Most patients with lateral epicondylitis can be treated conservatively with success. Radiological evaluation should be performed in therapy-resistant cases. In the case of partial or complete rupture of the extensor origin, operative therapy is indicated.

Long-term results of breast-conserving treatment for early-stage breast cancer in Japanese women from multicenter investigation

International Nuclear Information System (INIS)

Ohsumi, Shozo; Takashima, Shigemitsu; Sakamoto Goi

2003-01-01

Although many clinical data regarding breast-conserving treatment have already been reported from European and North American countries, few clinical data with long-term follow-up have been reported from Japan. We collected information on therapeutic and possible or developed prognostic factors and follow-up data for Japanese women who had received breast-conserving treatment consisting of wide excision of the primary tumor, axillary dissection and radiotherapy for unilateral breast cancer considered suitable for breast-conserving treatment from 18 Japanese major breast cancer treating hospitals; 1561 patients were registered. The median follow-up period was 77 months. Five-year disease-free and overall survival rates were 89.4 and 95.9%, respectively. The 5-year local recurrence-free rate was 96.3%. The patients with histologically positive margins (P<0.0001) or estrogen receptor negative tumor (P=0.0340) or younger than 40 years old (P<0.0001) developed statistically significantly more local recurrences. Adjuvant endocrine therapy was essential for the estrogen receptor positive patients to have a lower local recurrence rate. Endocrine therapy did not change the local recurrence rate among estrogen receptor negative patients at all. Multivariate analysis showed histological margin status and the combination of estrogen receptor status and endocrine therapy were independent prognostic factors for local recurrence. The 5-year local recurrence rate of Japanese breast cancer patients who were treated with breast-conserving treatment using radiotherapy was 3.7%. Independent prognostic factors for local recurrence were histological margin status and the combination of estrogen receptor status and adjuvant endocrine therapy. (author)

WLCI researchers employ new approaches to help managers conserve deer migrations

Science.gov (United States)

Allen, Leslie A.; Kauffman, Matthew J.

2012-01-01

Elk, mule deer, pronghorn antelope, moose, and bighorn sheep are iconic animals of the American West. These hooved animals, known as ungulates, commonly travel 30–60 miles between seasonal ranges. These migrations between winter and summer ranges are vital for survival and reproduction. As habitat fragmentation continues, the conservation of ungulate migration routes has received considerable attention in the West and across the globe. For example, it is estimated that many ungulate migration routes in the Greater Yellowstone Ecosystem have already been lost. The traditional migration routes of Wyoming ungulates are threatened by unprecedented levels of energy development and by increasing levels of rural ranchette development (including fences, structures, and roads). In the past, migration corridors have been mapped based primarily on the expert opinions of state game managers, but long-term conservation of Wyoming's ungulate migration routes requires a better understanding of migration ecology and more sophisticated management tools. Wyoming Landscape Conservation Initiative (WLCI) researchers investigated the migration of a large mule deer herd across the Dad and Wild Horse winter ranges in southwest Wyoming, where 2,000 gas wells and 1,609 kilometers of pipelines and roads have been proposed for development.

Changes in patient's quality of life comparing conservative and surgical treatment of venous leg ulcers.

Science.gov (United States)

Jankūnas, Vytautas; Rimdeika, Rytis; Jasenas, Marius; Samsanavicius, Donatas

2004-01-01

Leg ulcers of different etiology disable up to 1% of total population, and up to 15% individuals over 70 years old. It is an old disease, which troubles the patients and medical personnel and is hard to cure. It might take several years to cure the ulcer fully. Most of the patients with leg ulcers are being treated at home, not in the outpatient departments or hospitals; therefore there is not much information on how the ulcer affects the patient's everyday life and its quality. The researchers often analyze only the financial part of this disorder forgetting its human part: pain, social isolation, and decreased mobility. There are many questionnaires and methods to analyze the quality of life of the patients with leg ulceration. It is often unclear if we should treat the ulcer conservatively for a long time or if part of resources should be used for operation (skin grafting) and the time of treatment should be shortened. To see the advantage of both methods and the influence of the ulcer treatment to the quality of life we decided to estimate the functionality of surgical and conservative treatment. We have analyzed the case histories and the data of special questionnaires of 44 patients, which were treated in Department of Plastic Surgery and Burns of Kaunas University of Medicine Hospital in the period of 2001 January-2004 February and had large trophic leg ulcers (m=254 cm2) for 6 months or more. Ten patients were treated conservatively and 34 patients were treated by skin grafting. All of them were interviewed after 3-6 months. We found that the pain in the place of the ulcers has decreased for the patients, who were treated surgically. By making the differences of the pain more exact we found out, that the patients have been feeling pain before the operation and when interviewing them the second time they told that they felt discomfort, not pain. The intensity of pain remained the same for the patients treated conservatively. The regression of pain also

On filament structure and propagation within a commercial plasma globe

International Nuclear Information System (INIS)

Burin, M. J.; Simmons, G. G.; Ceja, H. G.; Zweben, S. J.; Nagy, A.; Brunkhorst, C.

2015-01-01

The filamentary discharge seen within commercial plasma globes is commonly enjoyed yet not well understood. Here, we investigate the discharge properties of a plasma globe using a variable high voltage amplifier. We find that increasing voltage magnitude increases the number of filaments while leaving their individual structure basically unchanged, a result typical of dielectric barrier discharges. The frequency of the voltage also affects filament population but more significantly changes filament structure, with more diffuse filaments seen at lower frequencies. Voltage polarity is observed to be important, especially at lower frequencies, where for negative-gradient voltages the discharge is more diffuse, not filamentary. At late stages of the discharge circular structures appear and expand on the glass boundaries. We find no trend of discharge speed with respect to voltage variables, though this may be due to manufacturer sample-to-sample variation. Each voltage cycle the discharge expands outward at ∼10–15 km/s, a speed significantly higher than the estimated electron drift yet considerably lower than that observed for most streamers. We discuss the physics of these observations and their relation to similar discharges that can be found within nature and industry

Effectiveness of using ultrasound therapy and manual therapy in the conservative treatment of calcaneal spur – pilot study

Directory of Open Access Journals (Sweden)

Twarowska Natalia

2016-06-01

Full Text Available Introduction: Calcaneal spur is a pathology of the fibrocartilage enthesis of the Achilles tendon and plantar fascia or a pathology of the mixed enthesis of the flexor digitorum brevis muscle. Ultrasound therapy is commonly applied in the conservative treatment of a calcaneal spur. Foot muscle strengthening exercises, stretching exercises and soft tissue therapy are indicated as effective methods of conservative treatment. The aim of the study was to compare and assess the effects of ultrasound therapy and selected techniques of manual therapy on pain level and functional state in patients with calcaneal spur.

Estimating Wet Bulb Globe Temperature Using Standard Meteorological Measurements

International Nuclear Information System (INIS)

Hunter, C.H.

1999-01-01

The heat stress management program at the Department of Energy''s Savannah River Site (SRS) requires implementation of protective controls on outdoor work based on observed values of wet bulb globe temperature (WBGT). To ensure continued compliance with heat stress program requirements, a computer algorithm was developed which calculates an estimate of WBGT using standard meteorological measurements. In addition, scripts were developed to generate a calculation every 15 minutes and post the results to an Intranet web site

How Cool was the Eclipse? Atmospheric Measurements and Citizen Science via NASA's GLOBE Observer

Science.gov (United States)

Weaver, K. L. K.; Riebeek Kohl, H.

2017-12-01

The solar eclipse of 2017 presented an extraordinary opportunity to engage the public in shared science activity across the entire United States. While a natural focus of the eclipse was on astronomy and heliophysics, there was also an opening for excellent connections to Earth science. Because of the excitement of the event, many people gathered for long periods before and after totality, a perfect opportunity for observations and data collection to explore the impact of the eclipse on the atmosphere. The data was collected via NASA's GLOBE Observer app, a subset of the Global Learning and Observations to Benefit the Environment Program, a citizen science project which has been active for more than 20 years training teachers to collect many different types of environmental science data with their students. GLOBE Observer expands that audience to citizen scientists who might not be connected to a school, but are still interested in collecting data. In addition to the clouds observations that are normally part of GLOBE Observer, a special temporary protocol was added for the eclipse to include air temperature. Both types of measurements were collected at regular intervals for several hours before and after the point of maximum eclipse. By crowdsourcing data from all across the United States, on and off the path of totality, the hope was to be able to see patterns that wouldn't be apparent with fewer data points. In particular, there are few sources of detailed cloud data from the ground, including cloud type as well as overall cloud cover, especially as collected during a unique natural experiment such as an eclipse. This presentation will report preliminary results of the GLOBE Observer eclipse citizen science project, including participation totals and impact, data site distribution, as well as early analyses of both temperature and cloud data.

Two-stage structural development of a Paleozoic auriferous shear zone at the Globe-Progress deposit, Reefton, New Zealand

International Nuclear Information System (INIS)

Milham, L.; Craw, D.

2009-01-01

The Globe-Progress gold deposit at Reefton is hosted in a curvilinear mineralised zone that cuts Paleozoic Greenland Group basement metagreywackes. Two discrete phases of mineralisation have resulted in the formation of five different ore types along the shear. An initial phase of mineralisation formed hydrothermal quartz veins and associated Au, As, and S enrichment, with low-grade mineralised host rock. These quartz veins and mineralised host rocks form the outer regions of the mineralised zone. A second hydrothermal phase introduced Sb, Au, As, and S during brittle shear deformation focused on the pre-existing mineralised rocks. This deformation and mineralisation resulted in the formation of metre-scale cataclasite ore and quartz breccia from mineralised host rock and hydrothermal quartz veins, respectively. Cataclasite was derived from argillite layers in the host rock, from which Na, Fe, and Mg have been leached during mineralisation; Al, Ti, and Cr have been conserved; and there has been minor enrichment in Sr, Pb, Zn, and Cu. No quartz was added to the cataclasite or quartz breccia during mineralisation, but some quartz recrystallisation occurred locally, and quartz clasts were physically incorporated into the cataclasite during deformation. The presence of euhedral sulfides in the cataclasite (40% of total sulfides), late-stage undeformed stibnite veins infilling breccia (1-5 cm 3 scale), and undeformed free gold in quartz breccia, imply that the second phase of mineralisation persisted both during and after cataclasis and brecciation. Antimony deposition is greatest in the central cataclasite, up to 6 wt%, and locally in the quartz breccia where stibnite veins are present. Concentrations of Sb decrease with distance from the shear zone. The second, Sb-rich phase of mineralisation in the Globe-Progress deposit resembles similar Sb-rich overprints in the correlative Victorian goldfield of Australia. (author). 38 refs., 10 figs., 1 tab.

The International Globe at Night Citizen-Science Campaign: Shedding Light on Light Pollution

Science.gov (United States)

Walker, C. E.; Pompea, S. M.

2013-12-01

For 8 years now, the Globe at Night campaign has invited citizen-scientists worldwide to measure and record the brightness of their night sky by hunting for the faintest stars in a particular constellation. Students for science projects and scientists for research use the data to monitor levels of brightness or 'light pollution' around the world. They also use the Globe at Night data to understand light pollution's effects on energy consumption, plants, wildlife and human health, as well as our ability to enjoy a starry night sky. The dates of the campaign for 2014 have been extended to every month during the year. Ten days each month (when the Moon is not up between 8pm and 10pm) are the recommended times to take measurements for the campaign. However, one can participate at other times and dates, as long as the Moon is not in the night sky and it is more than an hour after sunset or more than an hour before sunrise. New in 2014 will be an Android app that will allow you to input visual measurements anytime the Moon is not up. Also possibly included will be an iPhone app that will take sky brightness measurements. The campaign dates and the 5 easy steps to participating in the campaign are listed at www.globeatnight.org. You do not need to register. Once on the report page, you enter your location, date and time (automatic for a smart device). You find the constellation of the month in the night sky. (Help is on the website.) Then you choose which chart looks most like what you see toward the constellation. Choose the icon for how clear or cloudy it is and hit the submit button and you are done! The fifth step is returning later to the website to compare your observations on the world map to others from around the globe. Included on the Globe at Night website are many helpful resources and tools from finding the constellations used in the campaign, to understanding concepts like light pollution, to games that test your expertise in choosing 'limiting magnitudes

Coming of spring in Europe and on Day Night Year Globe

Science.gov (United States)

Marković-Topalović, Tatjana; Božić, Mirjana; Stojićević, Goran

2014-05-01

Day and night cycles, change of seasons, secular variations of climate on Earth are phenomena that depend on insolation of the Earth, its internal rotation and the orientation of its axis with respect to the Sun. For teaching about these phenomena, we have been using, since 2011, the outdoor globe that has the same orientation in space as the Earth. We call it Day Night Year Globe (DING). It was erected in the Center for advanced education of teachers in Šabac, Serbia [1]. Such globes were also erected in the Weizmann Institute in Israel, near the Max Valier Observatory in Italy, in the courtyard of the Tre University in Rome, in the Science Park in Zurich. During 2010 and 2011, the High Medical School took part and coordinated the realization of the Greenwave project [2] in the Šabac region. Twenty-two teachers, in seven primary schools, inspired and instructed their students to observe how exactly spring arrives and moves across Europe. Their task was to measure on daily basis: wind speed, temperature and rain precipitation. They also recorded sightings of species (barn swallow and frog spawns), common to all European countries, and of local species, which act as early indicators of the arrival of spring. The scientific contribution of the Šabac team consisted of correlating these observations and observations of changes of illumination on DING. During one sunny day, students observe the mapping of Earth's daily rotation onto DING. By observing the circle of illumination, day by day, students see how the inclination of this circle changes during the year. At the spring equinox the circle of illumination lies along the meridian. Our idea was that participants in other country could incorporate observations on DING, or a hands-on globe with two-rotation axes, properly oriented. We tried to induce interest for this idea to the authors and leaders of the Greenwave project. In Milanković's theory of the climate change of Earth, the orientation of Earth's axis with

Reconstruction versus conservative treatment after rupture of the anterior cruciate ligament: cost effectiveness analysis

Directory of Open Access Journals (Sweden)

Farshad Mazda

2011-11-01

Full Text Available Abstract Background The decision whether to treat conservatively or reconstruct surgically a torn anterior cruciate ligament (ACL is an ongoing subject of debate. The high prevalence and associated public health burden of torn ACL has led to continuous efforts to determine the best therapeutic approach. A critical evaluation of benefits and expenditures of both treatment options as in a cost effectiveness analysis seems well-suited to provide valuable information for treating physicians and healthcare policymakers. Methods A literature review identified four of 7410 searched articles providing sufficient outcome probabilities for the two treatment options for modeling. A transformation key based on the expert opinions of 25 orthopedic surgeons was used to derive utilities from available evidence. The cost data for both treatment strategies were based on average figures compiled by Orthopaedic University Hospital Balgrist and reinforced by Swiss national statistics. A decision tree was constructed to derive the cost-effectiveness of each strategy, which was then tested for robustness using Monte Carlo simulation. Results Decision tree analysis revealed a cost effectiveness of 16,038 USD/0.78 QALY for ACL reconstruction and 15,466 USD/0.66 QALY for conservative treatment, implying an incremental cost effectiveness of 4,890 USD/QALY for ACL reconstruction. Sensitivity analysis of utilities did not change the trend. Conclusion ACL reconstruction for reestablishment of knee stability seems cost effective in the Swiss setting based on currently available evidence. This, however, should be reinforced with randomized controlled trials comparing the two treatment strategies.

Curie-therapy for the conservative treatment of 304 choroidal melanomas in the Catalonia Oncology Institute

International Nuclear Information System (INIS)

Riou, O.; Gutierrez, C.; Pera, J.; Martinez, E.; Caminal, J.M.; Modolell, I.; Navarro, V.; Guedea, F.

2011-01-01

The authors report an analysis of results obtained on 304 patients who have been treated by curie-therapy for a non-metastatic choroidal melanoma. They address the treatment (exclusive curie-therapy, local relapse, and adjuvant surgery), the treatment type (iodine-125 plate, ruthenium plate, and dose level), the survival, metastatic evolutions, toxicity occurrence, and vision quality. In most of the cases, curie-therapy results in ocular conservation and in an acceptable vision. Short communication

Breast-conserving therapy in patients with bilateral breast cancer: Do today's treatment choices burn bridges for tomorrow?

International Nuclear Information System (INIS)

Gilroy, Jeffrey S.; Morris, Christopher G.; Mendenhall, Nancy Price

2005-01-01

Purpose: To determine how often initial treatment choices limit treatment options for subsequent breast cancer management in patients undergoing breast-conserving therapy (BCT), in particular with treatment of internal mammary nodes. Methods and Materials: Between January 1985 and June 2001, 464 women with pathologic Stage 0, I, and II (T0-2, N0-1) breast cancer underwent BCT at our institution. All 464 patients had computed tomography-based treatment planning. In patients with bilateral breast cancer, the planning computed tomography scans were used to determine the impact initial radiation therapy fields had on treatment options for subsequent contralateral breast cancer. Results: There were 500 breast cancers diagnosed in 464 patients. Thirty-six patients (8%) had bilateral breast cancer with 9 (2%) synchronous and 27 (6%) metachronous primaries. In 80 patients, the ipsilateral internal mammary nodes were explicitly treated. Initial breast cancer treatment choices impacted subsequent treatment decisions for the contralateral breast in only 2 of 464 patients (0.4%) in the study: 2 of 80 patients (2.5%) whose internal mammary nodes were treated, and 2 of 27 patients (7.4%) who developed metachronous bilateral breast cancer. Conclusions: Initial BCT, including internal mammary node irradiation, rarely compromised future contralateral breast-conserving therapy

Design, Development, and Maintenance of the GLOBE Program Website and Database

Science.gov (United States)

Brummer, Renate; Matsumoto, Clifford

2004-01-01

This is a 1-year (Fy 03) proposal to design and develop enhancements, implement improved efficiency and reliability, and provide responsive maintenance for the operational GLOBE (Global Learning and Observations to Benefit the Environment) Program website and database. This proposal is renewable, with a 5% annual inflation factor providing an approximate cost for the out years.

Variation of Phenolic Content in Globe Artichoke in Relation to Biological, Technical and Environmental Factors

Directory of Open Access Journals (Sweden)

Sara Lombardo

2009-12-01

Full Text Available In Italy, globe artichoke production is prevailingly concentrated in the South and islands, where it provides an important contribution to the agricultural economy. In recent years, there has been a renewed interest in this crop as a promising source of polyphenols, a heterogeneous class of secondary metabolites characterized by various healthy properties well-documented in literature. The phenolic fraction, present in the different artichoke plant parts, varies widely in relation to biotic and abiotic factors. Therefore, the present study aimed at evaluating the variation of phenolic content in globe artichoke in relation to biological, technical and environmental factors. Two field-experiments were carried out in Sicily (South Italy in two representative cultivation areas, in order to examine the effects of genotype, head fraction, season conditions, planting density and arrangement on the globe artichoke phenolic concentration. Both the total polyphenols and the individual phenolic compounds detected were notably genotype- dependent. Particularly, the high level of caffeoylquinic acids (chlorogenic acid, among others and apigenin 7- O-glucuronide, reported respectively by “Violetto di Sicilia” and “Romanesco clone C3”, could be used to encourage globe artichoke fresh consumption. Total polyphenols content also resulted more abundant in specific accumulation sites within the inflorescence, such as the floral stem and receptacle, and for most of genotypes it decreased during the second year in response to the different meteorological conditions. Additionally, total polyphenols content significantly and linearly increased as plant density increased from 1.0 to 1.8 plant m-2 and it significantly increased by 13% passing from single to twin rows plant arrangement.

Variation of Phenolic Content in Globe Artichoke in Relation to Biological, Technical and Environmental Factors

Directory of Open Access Journals (Sweden)

Giovanni Mauromicale

2011-02-01

Full Text Available In Italy, globe artichoke production is prevailingly concentrated in the South and islands, where it provides an important contribution to the agricultural economy. In recent years, there has been a renewed interest in this crop as a promising source of polyphenols, a heterogeneous class of secondary metabolites characterized by various healthy properties well-documented in literature. The phenolic fraction, present in the different artichoke plant parts, varies widely in relation to biotic and abiotic factors. Therefore, the present study aimed at evaluating the variation of phenolic content in globe artichoke in relation to biological, technical and environmental factors. Two field-experiments were carried out in Sicily (South Italy in two representative cultivation areas, in order to examine the effects of genotype, head fraction, season conditions, planting density and arrangement on the globe artichoke phenolic concentration. Both the total polyphenols and the individual phenolic compounds detected were notably genotype- dependent. Particularly, the high level of caffeoylquinic acids (chlorogenic acid, among others and apigenin 7- O-glucuronide, reported respectively by “Violetto di Sicilia” and “Romanesco clone C3”, could be used to encourage globe artichoke fresh consumption. Total polyphenols content also resulted more abundant in specific accumulation sites within the inflorescence, such as the floral stem and receptacle, and for most of genotypes it decreased during the second year in response to the different meteorological conditions. Additionally, total polyphenols content significantly and linearly increased as plant density increased from 1.0 to 1.8 plant m-2 and it significantly increased by 13% passing from single to twin rows plant arrangement.

Report on the 2016 conference Tax Treaty Case Law Around the Globe

NARCIS (Netherlands)

van Hulten, Mart; Jallai, Ave-Geidi

2016-01-01

Each year the international conference Tax Treaty Case Law Around the Globe provides a forum to discuss with outstanding experts of the relevant jurisdictions the most important and interesting tax treaty cases which recently have been decided all over the world. This article provides a report on

The Comparison of Double J Stent Insertion and Conservative Treatment Alone in Severe Pure Gestational Hydronephrosis: A Case Controlled Clinical Study

Science.gov (United States)

Çeçen, Kürşat; Ülker, Kahraman

2014-01-01

Objective. Management options of gestational hydronephrosis are based on the coexisting stone disease, pyelonephritis, and renal disease. However, the management option and its consequences in the absence of a coexisting disease state are not clear. In this study we aimed to compare the effectiveness of conservative treatment and double J insertion in symptomatic pure gestational hydronephrosis. Material and Methods. The data of the women with severe pure gestational hydronephrosis over a nine-year period was collected retrospectively. The included women were grouped into two according to receiving double J stent insertion or conservative treatments. Results. Double J insertion and conservative treatment groups included 24 and 29 women, respectively. Hydronephrosis was demonstrated on the right, left, or both kidneys in 37 (70%), 13 (24%), and 3 (6%) women, respectively. None of the participants gave birth prior to the 37th week. The demographics, initial pain scores, the severity of the hydronephrosis during first admission, and pain scores one week after the interventions did not differ significantly between groups (P > 0.05). Similarly, the rates of complications, postpartum pain scores, and permanent hydronephrosis did not differ between groups (P > 0.05). Conclusion. Double J insertion in symptomatic pure gestational hydronephrosis adds no benefit to conservative treatment. PMID:24574939

The Comparison of Double J Stent Insertion and Conservative Treatment Alone in Severe Pure Gestational Hydronephrosis: A Case Controlled Clinical Study

Directory of Open Access Journals (Sweden)

Kürşat Çeçen

2014-01-01

Full Text Available Objective. Management options of gestational hydronephrosis are based on the coexisting stone disease, pyelonephritis, and renal disease. However, the management option and its consequences in the absence of a coexisting disease state are not clear. In this study we aimed to compare the effectiveness of conservative treatment and double J insertion in symptomatic pure gestational hydronephrosis. Material and Methods. The data of the women with severe pure gestational hydronephrosis over a nine-year period was collected retrospectively. The included women were grouped into two according to receiving double J stent insertion or conservative treatments. Results. Double J insertion and conservative treatment groups included 24 and 29 women, respectively. Hydronephrosis was demonstrated on the right, left, or both kidneys in 37 (70%, 13 (24%, and 3 (6% women, respectively. None of the participants gave birth prior to the 37th week. The demographics, initial pain scores, the severity of the hydronephrosis during first admission, and pain scores one week after the interventions did not differ significantly between groups (P>0.05. Similarly, the rates of complications, postpartum pain scores, and permanent hydronephrosis did not differ between groups (P>0.05. Conclusion. Double J insertion in symptomatic pure gestational hydronephrosis adds no benefit to conservative treatment.

Successful conservative treatment of enterocutaneous fistula with cyanoacrylate surgical sealant: case report.

Science.gov (United States)

Musa, N; Aquilino, F; Panzera, P; Martines, G

2017-01-01

Enterocutaneous (EC) fistula is an abnormal communication between the gastrointestinal tract and the skin. The majority of EC fistulas result from surgery. Only 15-25% of EC fistulas are spontaneous and they often result from underlying diseases such as Crohn's disease, radiation and chemotherapy. A 62-year old woman who, in 2012, underwent Pylorus-preserving cephalic pancreaticoduodenectomy (PPPD sec. Traverso-Longmire), due to an advanced pancreatic ductal adenocarcinoma (pT3N1M1). After surgery, the patient underwent chemotherapy with folfirinox regimen. In December 2016, as a result of the appearance of metastatic liver lesions and perianastomotic recurrence, the patient underwent second line treatment with Gemcitabine and pab-paclitaxel. After five months from the beginning of this new second line therapy she presented an EC fistula. The fistula of the patient was successfully treated with total parenteral nutrition and with percutaneous injection of cyanoacrylic sealant. The result suggests the advisability of percutaneous injection of sealant devices, such as cyanoacrylate glue; in order to successfully control stable Enterocutaneous fistulas with acceptable morbidity and mortality especially in particular situations, such as, with low output EC fistulas without signs of complications or on patients considered not suitable for surgery, a conservative approach could ensure the control of the fistula. This approach is easy and safe, viable and useful for future trials on the efficacy in conservative treatment of EC fistula.

2009 events in the Globe

CERN Multimedia

2009-01-01

Globe of Science and Innovation 1st floor - Route de Meyrin, 1211 Geneva Mini-Einstein: physics for totsWednesdays from 14:30 to 15:30 January 2009: 14, 21, 28 and February 2009: 11, 18, 25 CERN is offering a series of workshops designed to teach the ABC of physics to the very young. Games and hands-on activities based on notions such as weight and waves will stimulate the children’s curiosity and initiate them into the world of science. Workshop in French for accompanied 4-to-6-year-olds. Free of charge, please book on +41 (0)22 767 76 76 Interactive exhibition Superconductivity... magical attraction Special opening from Tuesday, 13 January, to Saturday, 31 January 2009 Tuesdays and Wednesdays from 2.00 p.m. to 5.30 p.m. and Saturdays from 9 a.m. to 5.00 p.m. Following the success at the end of last year, the exhibition "Superconductivity... magical attraction" will be extended until the end of January. The phenomenon of sup...

On stage at the Globe

CERN Document Server

2005-01-01

The Globe's first season this year is to be rounded off with two shows that are in perfect keeping with the centenary of the death of Jules Verne and Albert Einstein's theory of relativity. 'Signé Jules Verne' (Signed Jules Verne) The Miméscope company, which has already thrilled audiences at CERN with shows such as the 'Oracle of Delphi' and, more recently, 'Point de Suspension', returns with an interactive show entitled 'Signé Jules Verne'. Imagine a slightly crazy machine, which rolls along on wheels, floats, flies or moves in any other way you like, as long as it works on scientific principles. This is the task that Jules Verne sets his audience. Experiments, models, drawings, blueprints, he's interested in them all. In its typical style, Miméscope has created a world of enchantment that combines theatre, choreography, music and lighting effects in a show that evolves as a function of its audience. Performances at 3.00 p.m. on 4, 7, 10 and 11 December An interactive show for the general public...

Mechanical instability after acute ankle ligament injury: randomized prospective comparison of two forms of conservative treatment

OpenAIRE

Prado, Marcelo Pires; Fernandes, Tulio Diniz; Camanho, Gilberto Luis; Mendes, Alberto Abussamra Moreira; Amodio, Daniel Tassetto

2013-01-01

OBJECTIVE: This trial has the objective to investigate the incidence of mechanical ankle instability after the conservative treatment of first episode, severe ankle ligamentar lesions. This common lesion affects young, professional and physical active patients, causing important personal and economic consequences. There are difficulties related to adequate diagnosis and treatment for these lesions. METHOD: 186 patients with severe ankle ligament lesions were included in this trial. They ...

Endoscope-assisted conservative condylectomy combined with orthognathic surgery in the treatment of mandibular condylar osteochondroma.

Science.gov (United States)

Yu, Hongbo; Jiao, Feifei; Li, Biao; Zhang, Lei; Shen, Steve Guofang; Wang, Xudong

2014-07-01

Mandibular condylar osteochondroma (OC) results in asymmetric prognathism with facial morphologic and functional disturbance. The aim of this study was to explore the feasibility of endoscope-assisted conservative condylectomy combined with simultaneous orthognathic surgery in the treatment of condylar OC. Thirteen patients with OC of the mandibular condyle were enrolled in this study. With the aid of endoscope, condylar OC resection and conservative condylectomy were carried out via intraoral approach. A direct vision of the magnified and illuminated operative field was realized. Simultaneous orthognathic surgery was used to correct facial asymmetry and malocclusion. All patients healed uneventfully. No facial nerve injury and salivary fistula occurred. Facial symmetry and morphology were greatly improved, and stable occlusion was obtained in all cases. The patients showed no signs of recurrence and temporomandibular joint ankylosis in the 16 to 54 months of follow-up. Endoscope-assisted tumor resection and condylectomy combined with simultaneous orthognathic surgery provide us a valuable option in the treatment of mandibular condylar OC.

Conservative treatment of breast ductal carcinoma in situ: results of an Italian multi-institutional retrospective study

International Nuclear Information System (INIS)

Vidali, Cristiana; Neri, Stefano; Pietta, Nicoletta; Caffo, Orazio; Aristei, Cynthia; Bertoni, Filippo; Bonetta, Alberto; Guenzi, Marina; Iotti, Cinzia; Leonardi, Maria Cristina; Mussari, Salvatore

2012-01-01

The incidence of ductal carcinoma in situ (DCIS) has increased markedly in recent decades. In the past, mastectomy was the primary treatment for patients with DCIS, but as with invasive cancer, breast-conserving surgery followed by radiation therapy (RT) has become the standard approach. We present the final results of a multi-institutional retrospective study of an Italian Radiation Oncology Group for the study of conservative treatment of DCIS, characterized by a very long period of accrual, from February 1985 to March 2000, and a median follow-up longer than 11 years. A collaborative multi-institutional study was conducted in Italy in 10 Radiation Oncology Departments. A consecutive series of 586 women with DCIS histologically confirmed, treated between February 1985 and March 2000, was retrospectively evaluated. Median age at diagnosis was 55 years (range: 29–84); 32 patients were 40 years old or younger. All women underwent conservative surgery followed by whole breast RT. Irradiation was delivered to the entire breast, for a median total dose of 50 Gy; the tumour bed was boosted in 295 cases (50%) at a median dose of 10 Gy. After a median follow-up of 136 months (range: 16–292 months), 59/586 patients (10%) experienced a local recurrence: invasive in 37 cases, intraductal in 20 and not specified in two. Salvage mastectomy was the treatment of choice in 46 recurrent patients; conservative surgery in 10 and it was unknown in three patients. The incidence of local recurrence was significantly higher in women younger than 40 years (31.3%) (p= 0.0009). Five patients developed distant metastases. Furthermore 40 patients developed a contralateral breast cancer and 31 a second primary tumour in a different site. The 10-year actuarial overall survival (OS) was 95.5% and the 10-year actuarial disease-specific survival (DSS) was 99%. Our results are consistent with those reported in the literature. In particular it has been defined the importance of young age (40

[Is radiotherapy of the lymph node stages useful after the conservative treatment of the initial stage of breast carcinoma?].

Science.gov (United States)

Gava, A; Coghetto, F

1989-05-01

Twenty-four lectures were reviewed of the XXXIII SIRMN National Congress (Rome, October 1988) on the conservative radiosurgical treatment of breast cancer. A whole of 3462 cases were divided into 2 groups: group A--2824 patients who underwent targeted radiotherapy after conservative surgery (mostly quadrantectomy)--and group B--638 patients where, in case of N+ and internal quadrant tumors, irradiation was extended to lymph nodes. No significant differences were demonstrated between group A and group B as far as loco-regional relapses were concerned. Thus, no significant advantage seems to be yielded by lymph node irradiation in the early treatment of breast cancer.

Is face-only photographic view enough for the aesthetic evaluation of breast cancer conservative treatment?

DEFF Research Database (Denmark)

Cardoso, Maria João; Magalhães, André; Almeida, Teresa

2008-01-01

The breast cancer conservative treatment. cosmetic results (BCCT.core) is a new software tool created for the automatic and objective evaluation of the aesthetic result of BCCT. It makes use of a face-only photographic view of each patient and might thus have been considered insufficient for an a...

Conservative management of vestibular schwannoma--a prospective cohort study: treatment, symptoms, and quality of life.

Science.gov (United States)

Breivik, Cathrine Nansdal; Varughese, Jobin K; Wentzel-Larsen, Tore; Vassbotn, Flemming; Lund-Johansen, Morten

2012-05-01

One hundred ninety-three patients with sporadic unilateral vestibular schwannoma given conservative management were enrolled in a prospective study. To evaluate the efficacy of conservative management and to determine the effect of an initial conservative management on the quality of life (QOL) and severity of audio vestibular symptoms. The patients underwent magnetic resonance imaging scans, clinical examination, and QOL assessment by 2 validated questionnaires, the Short Form-36 (SF-36) and Glasgow Benefit Inventory (GBI). Using regression analysis of clustered data, we analyzed possible associations between tumor growth and symptoms and tested whether our earlier finding that vertigo is associated with reduced QOL could be verified. The median follow-up time was 43 months (range, 9-115 months; SD, 21.48 months). Results are based on 703 clinical controls and 642 (SF-36) and 638 (GBI) questionnaires. Seven patients were lost to follow-up. Approximately 40% of patients were in need of treatment during follow-up. We found a statistically significant association between tinnitus and vertigo and tumor growth. Vertigo was found to significantly reduce QOL. There was a significant drop in the Social Function subscales of both SF-36 and GBI, possibly attributable to progressive hearing loss. Otherwise, there was no overall trend toward any change in QOL during the observation period. In addition, QOL seemed to be little affected by treatment. There was a small but statistically significant improvement in vestibular complaints and no change in the occurrence of tinnitus. Except for hearing loss caused by surgery, treatment did not affect symptoms or QOL significantly. Growth was associated with the occurrence of tinnitus and balance problems.

Accumulation of cynaropicrin in globe artichoke and localization ofenzymes involved in its biosynthesis

NARCIS (Netherlands)

Eljounaidi, K.; Comino, C.; Moglia, A.; Cankar, K.; Genre, A.; Hehn, A.; Bourgaud, F.; Beekwilder, J.; Lanteri, S.

2015-01-01

Globe artichoke (Cynara cardunculus var. scolymus) belongs to the Asteraceae family, in which one ofthe most biologically significant class of secondary metabolites are sesquiterpene lactones (STLs). Inglobe artichoke the principal STL is the cynaropicrin, which contributes to approximately 80% of

Stress energy of elastic globe in curved space and a slip-out force

International Nuclear Information System (INIS)

Sokolov, S.N.

1990-01-01

The energy of stresses in an elastic globe in the flat space and in curved space is expressed through scalar invariants of the curved space. This energy creates an additional force acting on elastic bodies in a gravitational field. 4 refs

Globe of Natural Hazard - A new assessment tool for risk managers

Science.gov (United States)

Siebert, A. C.

2009-04-01

A large number of tropical cyclones and the earthquake in Sichuan made 2008 one of the most devastating years on record. Throughout the world, more than 220,000 people died as a result of natural catastrophes this year. Overall losses totaled some US 200bn (2007: US 82bn). Insured losses in 2008 rose to US 45bn, about 50% higher than in the previous year. Mainly driven by high losses from weather-related natural catastrophes, 2008 was - on the basis of figures adjusted for inflation - even the third most expensive year on record for the insurance industry, exceeded only by the hurricane year of 2005 and by 1995, the year of the Kobe earthquake. Munich Re, a worldwide operating reinsurance company, is a world leader in terms of investigating risks from natural hazards of all kinds. 2008 has again shown the insurance industry how important it is to analyse risks like natural hazards and climate change in all their facets and to manage the insurance business accordingly. An excellent example of the wealth of knowledge Munich Re has developed in natural hazard assessment is the DVD "Globe of Natural Hazards". It combines the geoscientific data and findings Munich Re has accumulated over a period of 35 years. First devised as a wall-map in 1978, the product has established itself as a standard work for the identification, exposure assessment and risk management of natural hazards. Over 80,000 copies of the CD-ROM version of 2000 have been provided to clients - a mark achieved by no other service product in Munich Re's history. Since the beginning of 2009, the fully updated fourth-generation version has been available. The bilingual DVD (German and English) shows natural hazards and climate effects at a glance: the global maps are presented on a 3D globe, underlaid with satellite images. The hazard complexes of hail, tornado and winter storms have been completely revised and flood incorporated as a new hazard. Users can intuitively home in on and enlarge any location on

Enhancing Science Teacher Training Using Water Resources and GLOBE

Science.gov (United States)

Falco, James W.

2002-01-01

Heritage College, located on the Yakama Indian Reservation in south central Washington state, serves a multicultural, underserved, rural population and trains teachers to staff the disadvantaged school districts on and surrounding the reservation. In-service teachers and pre-service teachers in the area show strength in biology but have weak backgrounds in chemistry and mathematics. We are addressing this problem by providing a 2-year core of courses for 3 groups of 25 students (15 pre-service and 10 in-service teachers) using GLOBE to teach integrated physical science and mathematics. At the conclusion of the program, the students will qualify for science certification by Washington State. Water resources are the focal point of the curriculum because it is central to life in our desert area. The lack or excess of water, its uses, quality and distribution is being studied by using GIS, remote sensing and historical records. Students are learning the methodology to incorporate scientific protocols and data into all aspects of their future teaching curriculum. In addition, in each of the three years of the project, pre-service teachers attended a seminar series during the fall semester with presentations by collaborators from industry, agriculture, education and government agencies. Students used NASA educational materials in the presentations that they gave at the conclusion of the seminar series. All pre- and in-service teachers continue to have support via a local web site for Heritage College GLOBE participants.

Accumulation of cynaropicrin in globe artichoke and localization of enzymes involved in its biosynthesis.

Science.gov (United States)

Eljounaidi, K; Comino, C; Moglia, A; Cankar, K; Genre, A; Hehn, A; Bourgaud, F; Beekwilder, J; Lanteri, S

2015-10-01

Globe artichoke (Cynara cardunculus var. scolymus) belongs to the Asteraceae family, in which one of the most biologically significant class of secondary metabolites are sesquiterpene lactones (STLs). In globe artichoke the principal STL is the cynaropicrin, which contributes to approximately 80% of its characteristic bitter taste. Cynaropicrin content was assessed in globe artichoke tissues and was observed to accumulate in leaves of different developmental stages. In the receptacle, a progressive decrease was observed during inflorescence development, while the STL could not be detected in the inflorescence bracts. Almost undetectable amounts were found in the roots and inflorescence stems at the commercial stage. Cynaropicrin content was found to correlate with expression of genes encoding CcGAS, CcGAO and CcCOS, which are involved in the STL biosynthesis. A more detailed study of leaf material revealed that cynaropicrin predominantly accumulates in the trichomes, and not in the apoplastic cavity fluids. Analysis of the promoter regions of CcGAO and CcCOS revealed the presence of L1-box motifs, which confers trichome-specific expression in Arabidopsis, suggesting that cynaropicrin is not only stored but also synthesized in trichomes. A transient expression of GFP fusion proteins was performed in Nicotiana benthamiana plants: the CcGAS fluorescence signal was located in the cytoplasm while the CcGAO and CcCOS localized to the endoplasmatic reticulum. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

A comparison of behavioral and psychological characteristics of patients opting for surgical and conservative treatment for morbid obesity.

Science.gov (United States)

Kvalem, Ingela Lundin; Bergh, Irmelin; von Soest, Tilmann; Rosenvinge, Jan H; Johnsen, Tina Avantis; Martinsen, Egil W; Mala, Tom; Kristinsson, Jon A

2015-01-01

Little is known about the psychological prerequisites for weight loss maintenance after bariatric surgery. A first step in investigating whether existing knowledge of conservative weight loss treatment is applicable for lifestyle interventions postoperatively is to compare specific psychological characteristics at baseline. The aim of this study was to compare patients scheduled for bariatric surgery with patients receiving conservative treatment for morbid obesity on measures of behavioral and psychosocial characteristics considered predictors of their adoption of and adherence to long-term lifestyle recommendations. Baseline clinical and questionnaire data from the prospective "Oslo Bariatric Surgery Study" were used to examine potential differences between bariatric surgery patients (n = 301) and patients receiving conservative weight loss treatment (n = 261). The surgical group was characterized by their younger age (43.8 vs. 46.2 years, p changing their eating behaviors (OR = 1.80, 95 % CI 1.06, 1.93). The surgical patients were also less ready to change physical activity levels (OR = 0.59, 95 % CI 0.48, 0.73), had tried more types of unhealthy weight loss methods in the past (OR = 1.16, 95 % CI 1.01, 1.33), drank soda more frequently (OR = 1.24, 95 % CI 1.02, 1.50), had fewer binge eating episodes (OR = 0.38, 95 % CI 0.20, 0.71), and had more depressive symptoms (OR = 1.19, 95 % CI 1.09, 1.29). Patients opting for bariatric surgery had more positive expectations of the treatment outcomes and stronger beliefs in their ability to achieve these outcomes. Those starting conservative treatment had stronger beliefs in readiness to change physical activity levels. Future studies should explore the effect of interventions for bariatric surgery patients, promoting postoperative physical activity and stress realistic outcome expectations. The potential effects of incorporating this knowledge in intervention strategies remain to be

Breast conservation in the setting of contemporary multimodality treatment provides excellent outcomes for patients with occult primary breast cancer.

Science.gov (United States)

Rueth, Natasha M; Black, Dalliah M; Limmer, Angela R; Gabriel, Emmanuel; Huo, Lei; Fornage, Bruno D; Dogan, Basak E; Chavez-MacGregor, Mariana; Yi, Min; Hunt, Kelly K; Strom, Eric A

2015-01-01

To evaluate recurrence and survival for patients with occult (T0N+) breast cancer who underwent contemporary treatment, assessing outcomes for breast conservation and mastectomy. We performed a single-institution review of women with occult breast cancer presenting with axillary metastasis without identifiable breast tumor or distant metastasis. We excluded patients with tumors in the axillary tail or mastectomy specimen, patients with additional nonbreast cancer diagnoses, and patients with a history of breast cancer. Breast conservation was defined as axillary node dissection with radiation therapy, without breast surgery. We evaluated patient, tumor, treatment, and outcome variables. Patients were assessed for local, regional, and distant recurrences. Overall survival was calculated using the Kaplan-Meier method. Thirty-six patients met criteria for occult breast cancer. Most of these patients (77.8 %) had N1 disease. Fifty percent of cancers (n = 18) were estrogen receptor-positive; 12 (33.3 %) were triple-negative. All patients were evaluated with mammography. Thirty-five patients had breast ultrasound (97.2 %) and 33 (91.7 %) had an MRI. Thirty-four patients (94.4 %) were treated with chemotherapy and 33 (91.7 %) with radiotherapy. Twenty-seven patients (75.0 %) were treated with breast conservation. The median follow-up was 64 months. There were no local or regional failures. One distant recurrence occurred >5 years after diagnosis, resulting in a 5-years overall survival rate of 100 %. There were no significant survival differences between patients receiving breast conservation versus mastectomy (p = 0.7). Breast conservation-performed with contemporary imaging and multimodality treatment-provides excellent local control and survival for women with T0N+ breast cancer and can be safely offered instead of mastectomy.

Proteomic Analysis of PEG-Fractionated UV-C Stress-Response Proteins in Globe Artichoke

NARCIS (Netherlands)

Falvo, S.; Acquadro, A.; Albo, A.G.; America, A.H.P.; Lanteri, S.

2012-01-01

Plants respond to UV stress by producing antioxidant molecules and by altering their metabolism through the regulation of specific gene family members. Globe artichoke (Cynara cardunculus var. scolymus L.-Compositae family) is an attractive model species for studying the protein networks involved in

GLOBE Observer and the Association of Science & Technology Centers: Leveraging Citizen Science and Partnerships for an International Science Experiment to Build Climate Literacy

Science.gov (United States)

Riebeek Kohl, H.; Chambers, L. H.; Murphy, T.

2016-12-01

For more that 20 years, the Global Learning and Observations to Benefit the Environment (GLOBE) Program has sought to increase environment literacy in students by involving them in the process of data collection and scientific research. In 2016, the program expanded to accept observations from citizen scientists of all ages through a relatively simple app. Called GLOBE Observer, the new program aims to help participants feel connected to a global community focused on advancing the scientific understanding of Earth system science while building climate literacy among participants and increasing valuable environmental data points to expand both student and scientific research. In October 2016, GLOBE Observer partnered with the Association of Science & Technology Centers (ASTC) in an international science experiment in which museums and patrons around the world collected cloud observations through GLOBE Observer to create a global cloud map in support of NASA satellite science. The experiment was an element of the International Science Center and Science Museum Day, an event planned in partnership with UNESCO and ASTC. Museums and science centers provided the climate context for the observations, while GLOBE Observer offered a uniform experience and a digital platform to build a connected global community. This talk will introduce GLOBE Observer and will present the results of the experiment, including evaluation feedback on gains in climate literacy through the event.

Conservative treatment of immature teeth with apical periodontitis using triple antibiotic paste disinfection

OpenAIRE

Wang, Hsin-Ju; Chen, Yea-Huey Melody; Chen, Kuan-Liang

2016-01-01

The purpose of this report is to present conservative treatment for two immature premolars with apical periodontitis. A triple antibiotic paste was used to disinfect the root canal systems for revascularization. In both cases, residual vital pulp tissue was noted in the root canal system after the opening of each premolar. The canals in both cases were irrigated with copious sodium hypochlorite solution and medicated with a paste consisting of ciprofloxacin, metronidazole, and minocycline. Th...

Detection of salmonella on globe fruits using pulse excited magnetoelastic biosensors

Science.gov (United States)

Wikle, Howard C.; Du, Songtao; Prorok, Barton C.; Chin, Bryan A.

2015-05-01

This paper describes the results of a research project to investigate magnetoelastic (ME) biosensors actuated with a pulse excitation to measure the concentration of Salmonella Typhimurium of globe fruits. The ME biosensors are based on an acoustic wave resonator platform that is a freestanding (free-free) thin ribbon of magnetostrictive material with a lengthto- width ratio of 5:1. A biorecognition probe coated on the surface of the resonator platform binds with a targeted pathogen, i.e. E2 phage that binds with S. Typhimurium. The biosensor was actuated to vibrate longitudinally such that the resonant frequency depended primarily on the length of sensor and its overall mass. A pulsed excitation and measurement system was used to actuate micron scale ME biosensors to vibrate. The biosensor responds in a ring-down manner, a damped decay of the resonance amplitude, from which the resonant frequency was measured. An increase in mass due to the binding of the target pathogen resulted in a decrease in the resonant frequency. The pulsed excitation and measurement system that was developed under this effort and the characterization of its performance on the measurement of Salmonella concentrations on globe fruits is described.

Conservation et anthropisation en Afrique centrale

Directory of Open Access Journals (Sweden)

Vermeulen, C.

2015-01-01

Full Text Available Conservation and Anthropization in Central Africa. As we enter a millennium often referred to as Anthropocene, with reference to the influence never before seen in the history of a species namely the human being, world biodiversity declines at an accelerated pace. A pace of change so severe that researchers have difficulties describing the current phenomena. Wildlife in particular is seriously threatened, to such an extent that we speak about the biggest massive extinction of animal species ever to occur on Earth. Many regions of the globe, in particular Central Africa, thus see theirbiodiversity disappearing before it is even documented. With regard to its concerns about the sustainability of the environment, the journal Tropicultura now opens its columns to authors working in conservation and the relations between man and nature, and more particularly its wildlife. Stemming from a call for contributions directed at young active researchers in Central.Africa, this special issue is as diverse as the themes developed in conservation of this region. >From plains Gorillas of Cameroon to bushmeat consumption in Gabon and the participative management in Congo, intrepid scientists offer us an anthology of fascinating stories. Scattered at the edge of dense forests, in remote and sometimes dangerous areas, these researchers raise numerous questions about the future of wildlife in this part of the globe. A frightening future, since the threats seem more numerous than the solutions. Nevertheless, these articles also deliver a positive vision of the situation. They demonstrate the will of enthusiast conservationists to fight relentlessly for the preservation of our ecosystems. They also demonstrate the increasing implication of researchers from those regions to protect their incredible heritage and reconcile man and nature. If figures are disturbing and human population grows and expands perpetually, particularly in these countries, the interest for

GlobeLand30 as an alternative fine-scale global land cover map

DEFF Research Database (Denmark)

Jokar Arsanjani, Jamal; Tayyebi, A.; Vaz, E.

2016-01-01

land cover information such as developing countries. In this study, we look at GlobeLand30 of 2010 for Iran in order to find out the accuracy of this dataset as well as its implications. By having looked at 6 selected study sites around larger cities representing dissimilar eco-regions covering rural...

The effect of low dose rocuronium on globe position, muscle relaxation and ventilation in dogs: a clinical study.

Science.gov (United States)

Auer, Ulrike; Mosing, Martina; Moens, Yves P S

2007-01-01

The purpose of this study was to evaluate globe position, muscle relaxation and changes in ventilatory parameters after intravenous administration of 0.1 mg/kg rocuronium. Prospective clinical study. Sixteen dogs of different breeds, with a body weight of 22.1 +/- 13 kg and age of 5.6 +/- 2.8 years (mean +/- SD), were anesthetized for a short ophthalmic examination requiring central position of the globe. All dogs were premedicated with 0.005 mg/kg medetomidine and 0.1 mg/kg methadone IV. Anesthesia was induced with propofol to effect and maintained with 10 mg/kg/h propofol by continuous rate infusion. Following endotracheal intubation all dogs breathed 100% oxygen via an anesthetic circle system. Neuromuscular function was assessed with an acceleromyograph (TOF-Guard, Organon Teknika NV, Turnhout, Belgium) and by stimulation of the nervus peroneus superficialis. The ventilation parameters were measured using spirometry and capnography. After baseline measurements 0.1 mg/kg rocuronium was administered IV. Minute volume (MV), tidal volume (Vt), respiratory rate (RR), end expiratory carbon dioxide concentration (PE'CO(2)) and maximal depression of the response of the first twitch (T1) of train-of-four (TOF) stimulation and train-of-four ratio (TOFR) was measured. The change in the position of the globe was recorded. T1 decreased to 61 +/- 18% and the TOF ratio to 45 +/- 21% of baseline values. Both parameters returned to baseline after 9 min. There was no significant reduction in MV, TV and RR and no increase in PE'CO(2). The globe rotated to a central position of 45 +/- 7.7 s after administration of rocuronium and remained there for 23 +/- 10.8 min in all dogs. Rocuronium administered intravenously at a dose of 0.1 mg/kg to dogs causes a central position of the globe but minimal impairment of ventilation parameters.

Risk factors for recurrence after conservative treatment in early breast cancer; Preliminary report

Energy Technology Data Exchange (ETDEWEB)

Suh, C O; Chung, E J; Lee, H D; Lee, K S; Oh, K K; Kim, G E [Yonsei Univ., Seoul (Korea, Republic of). Coll. of Medicine

1997-12-01

To evaluate our experience in the breast-conserving treatment for early breast cancer with special regard to recurrence pattern and related risk factors. Two hundred and sixteen patients with AJC stage I and II beast cancer who received breast conserving treatment between January 1991 and December 1994 were evaluated. Age distribution ranged from 23-80 year old with a median age of 44. One hundred and seventeen patients had T1 lesions and 99 patients had T2 lesions. Axillary lymph nodes were involved in 73 patients. All patients received a breast conserving surgery (wide excision to quadrantectomy) and axillary node dissection followed by radiotherapy. Ninety six patients received chemotherapy before or after radiotherapy. During the follow-up period (3-60 months, median 30 months), local recurrence were noted in six patients (true; 3, elsewhere; 1, skin; 2). Sixteen patients developed distant metastases as the first sign of recurrence at 8-38 months (median 20 months) after surgery. Among them, three patients simultaneously developed local recurrence with distant metastases. Contralateral breast cancer developed in one patient and non-mammary cancers developed in three patients. The actuarial 5 year survival rate was 88.4% (stage I: 96.7%, stage IIa: 95.2%, stage IIb 69.9%). Age, T stage, number of involved axillary lymph nodes, and AJC stage were risk factors for distant metastases in univariate analysis. In the multivariate analysis, the number of involved axillary lymph nodes was the most significant risk factor for metastases. Local recurrence was not common in the early years after radiotherapy. Distant metastases occurred at a steady rate during the first three years and was more common in the patients with larger tumors, higher number of involved axillary nodes, and younger age. (author).

VISUALIZATION OF VGI DATA THROUGH THE NEW NASA WEB WORLD WIND VIRTUAL GLOBE

Directory of Open Access Journals (Sweden)

M. A. Brovelli

2016-06-01

Full Text Available GeoWeb 2.0, laying the foundations of Volunteered Geographic Information (VGI systems, has led to platforms where users can contribute to the geographic knowledge that is open to access. Moreover, as a result of the advancements in 3D visualization, virtual globes able to visualize geographic data even on browsers emerged. However the integration of VGI systems and virtual globes has not been fully realized. The study presented aims to visualize volunteered data in 3D, considering also the ease of use aspects for general public, using Free and Open Source Software (FOSS. The new Application Programming Interface (API of NASA, Web World Wind, written in JavaScript and based on Web Graphics Library (WebGL is cross-platform and cross-browser, so that the virtual globe created using this API can be accessible through any WebGL supported browser on different operating systems and devices, as a result not requiring any installation or configuration on the client-side, making the collected data more usable to users, which is not the case with the World Wind for Java as installation and configuration of the Java Virtual Machine (JVM is required. Furthermore, the data collected through various VGI platforms might be in different formats, stored in a traditional relational database or in a NoSQL database. The project developed aims to visualize and query data collected through Open Data Kit (ODK platform and a cross-platform application, where data is stored in a relational PostgreSQL and NoSQL CouchDB databases respectively.

Visualization of Vgi Data Through the New NASA Web World Wind Virtual Globe

Science.gov (United States)

Brovelli, M. A.; Kilsedar, C. E.; Zamboni, G.

2016-06-01

GeoWeb 2.0, laying the foundations of Volunteered Geographic Information (VGI) systems, has led to platforms where users can contribute to the geographic knowledge that is open to access. Moreover, as a result of the advancements in 3D visualization, virtual globes able to visualize geographic data even on browsers emerged. However the integration of VGI systems and virtual globes has not been fully realized. The study presented aims to visualize volunteered data in 3D, considering also the ease of use aspects for general public, using Free and Open Source Software (FOSS). The new Application Programming Interface (API) of NASA, Web World Wind, written in JavaScript and based on Web Graphics Library (WebGL) is cross-platform and cross-browser, so that the virtual globe created using this API can be accessible through any WebGL supported browser on different operating systems and devices, as a result not requiring any installation or configuration on the client-side, making the collected data more usable to users, which is not the case with the World Wind for Java as installation and configuration of the Java Virtual Machine (JVM) is required. Furthermore, the data collected through various VGI platforms might be in different formats, stored in a traditional relational database or in a NoSQL database. The project developed aims to visualize and query data collected through Open Data Kit (ODK) platform and a cross-platform application, where data is stored in a relational PostgreSQL and NoSQL CouchDB databases respectively.

Chemotherapy as an adjuvant to Radiotherapy in treatment of Retinoblastoma

International Nuclear Information System (INIS)

Ahmed, A.H.M.

2015-01-01

Retinoblastoma is the most common primary intraocular malignancy of childhood. A potentially curable cancer, its treatment has improved significantly over the last few decades. Various studies show that while enucleation remains the standard of care for advanced intraocular tumours, conservative modalities that can result in globe salvage and preservation of useful vision are being increasingly employed. Such modalities include systemic chemotherapy, focal consolidation with transpupillary thermo therapy, laser photocoagulation and cryotherapy, plaque brachytherapy, and delivery of local chemotherapy using subconjunctival, sub-tenon, or intra-arterial routes. When used alone or in combination, these treatment modalities can help in avoidance of external beam radiotherapy or enucleation, thus reducing the potential for long-term side effects, while salvaging useful vision. Radioactive plaque brachytherapy has an established role in selected patients with intraocular retinoblastoma. Local injections of chemotherapeutic agents via the sub-tenon or sub-conjunctival route have been used with varying degrees of success, usually as an adjunct to systemic chemotherapy. Intra-arterial ophthalmic artery delivery of melphalan has shown promising results.

Conservative care as a treatment option for patients aged 75 years and older with CKD stage V: a National survey in the Netherlands.

Science.gov (United States)

Susanto, Christopher; Kooman, J; Courtens, A M; Konings, C J A M

2018-01-01

Conservative care for patients aged 75 years and older with CKD stage 5 as a treatment option besides dialysis was proposed officially in the Netherlands in October 2016. This national survey showed the current implementation of this option in Netherlands nephrology departments. A web-based survey was sent to medical managers of 60 nephrology departments in the Netherlands in August 2016. Twenty-one medical managers (35%) completed the survey. The term "conservative care" is frequently used and well known. The estimated number of patients in whom the decision for maximal conservative care was made in 2015 was 310 of 2249 patients with CKD stage 5 age 75 years and older (range 5-50 patients per department). 164 patients became symptomatic and received no dialysis. There is no official registration for this treatment option and patient category. The practice patterns vary widely. Only one of 21 respondents reported a conservative care outpatient clinic. Formal training or education regarding conservative care is not available in most of departments. 95% of respondents discussed this treatment option with their patients. General practitioners are always being informed about their patient's decision. Their main role is providing or organizing palliative care support at the end of life and discussing advance care planning. Most respondents (86%) considered to include their patients in a prospective multicentre observational study, conservative care versus dialysis. Conservative care as a treatment option for patients with CKD stage 5 aged 75 years and older is well established. The practice patterns are varied in the Netherlands. Follow-up studies are needed to see whether the new multidisciplinary guideline facilitates harmonization of practice pattern. Funding is needed to optimize the implementation of conservative care.

Theory and practice of irradiation and other treatment procedures for conservation of cultural heritage

International Nuclear Information System (INIS)

Ponta, C.C.

1998-01-01

Promotional activities were developed for applications of the Romanian Multipurpose Irradiation Facility in various fields. Among these, the conservation of cultural heritage by irradiation is one of the targets taken into consideration from the design stage. A dedicated laboratory is part of the facility. The preparations for cultural heritage conservation already started. They included acquiring of theoretical and practical experience in this field and many contacts were done with museum and archive specialists in restoration and conservation. Being a quasi new borderline between the humanistic and technical areas, the conservation of cultural heritage needs pluri-disciplinary synthesis. Our work, mainly bibliographical, covers this complex picture focusing on conservation from different points of view: sources of degradation, technical conservation alternatives with pros and contras, cost/benefit and other aspects that must be taken into account when a conservation procedure is chosen. The paper aim is to assemble the abilities of those implicated in execution and decision. - The conservator perspective is the most important one. He has the privilege and responsibility in choosing the disinfestation procedure. His perspective is based on the knowledge of the material structure, of the specific way of material deterioration and of the biology of the aggressors. - The conservation procedures must have in view the protection of the persons that use the treated objects (museum custodian, archivist, archive researcher, visitor), i.e., the need for an ecologically friendly technology to ensure the protection of human beings and environment. This trend imposed the abandonment of fumigation with toxic vapours (persisting in treated items and slowly being released in museum and archives) giving credits to new clean methods, like irradiation. - The perspective of the operator that applies the conservation procedure is governed by technical and financial elements. Having

Successful conservation of global waterbird populations depends on effective governance

Science.gov (United States)

Amano, Tatsuya; Székely, Tamás; Sandel, Brody; Nagy, Szabolcs; Mundkur, Taej; Langendoen, Tom; Blanco, Daniel; Soykan, Candan U.; Sutherland, William J.

2018-01-01

Understanding global patterns of biodiversity change is crucial for conservation research, policies and practices. However, for most ecosystems, the lack of systematically collected data at a global level limits our understanding of biodiversity changes and their local-scale drivers. Here we address this challenge by focusing on wetlands, which are among the most biodiverse and productive of any environments and which provide essential ecosystem services, but are also amongst the most seriously threatened ecosystems. Using birds as an indicator taxon of wetland biodiversity, we model time-series abundance data for 461 waterbird species at 25,769 survey sites across the globe. We show that the strongest predictor of changes in waterbird abundance, and of conservation efforts having beneficial effects, is the effective governance of a country. In areas in which governance is on average less effective, such as western and central Asia, sub-Saharan Africa and South America, waterbird declines are particularly pronounced; a higher protected area coverage of wetland environments facilitates waterbird increases, but only in countries with more effective governance. Our findings highlight that sociopolitical instability can lead to biodiversity loss and undermine the benefit of existing conservation efforts, such as the expansion of protected area coverage. Furthermore, data deficiencies in areas with less effective governance could lead to underestimations of the extent of the current biodiversity crisis.

Successful conservation of global waterbird populations depends on effective governance.

Science.gov (United States)

Amano, Tatsuya; Székely, Tamás; Sandel, Brody; Nagy, Szabolcs; Mundkur, Taej; Langendoen, Tom; Blanco, Daniel; Soykan, Candan U; Sutherland, William J

2018-01-11

Understanding global patterns of biodiversity change is crucial for conservation research, policies and practices. However, for most ecosystems, the lack of systematically collected data at a global level limits our understanding of biodiversity changes and their local-scale drivers. Here we address this challenge by focusing on wetlands, which are among the most biodiverse and productive of any environments and which provide essential ecosystem services, but are also amongst the most seriously threatened ecosystems. Using birds as an indicator taxon of wetland biodiversity, we model time-series abundance data for 461 waterbird species at 25,769 survey sites across the globe. We show that the strongest predictor of changes in waterbird abundance, and of conservation efforts having beneficial effects, is the effective governance of a country. In areas in which governance is on average less effective, such as western and central Asia, sub-Saharan Africa and South America, waterbird declines are particularly pronounced; a higher protected area coverage of wetland environments facilitates waterbird increases, but only in countries with more effective governance. Our findings highlight that sociopolitical instability can lead to biodiversity loss and undermine the benefit of existing conservation efforts, such as the expansion of protected area coverage. Furthermore, data deficiencies in areas with less effective governance could lead to underestimations of the extent of the current biodiversity crisis.

Globe Artichoke Callus as an Alternative System for the Production of Dicaffeoylquinic Acids

NARCIS (Netherlands)

Moglia, A.; Menin, B.; Comino, C.; Lanteri, S.; Beekwilder, M.J.

2012-01-01

Globe artichoke leaves are highly rich in phenolic acids, in particular chlorogenic acid and dicaffeoylquinic acids. The latter are of particular interest since they can exert a stronger antioxidant activity, due to the presence of two adjacent hydroxyl groups on each of their phenolic rings. Plant

Emergent risk factors associated with eyeball loss and ambulatory vision loss after globe injuries.

Science.gov (United States)

Hyun Lee, Seung; Ahn, Jae Kyoun

2010-07-01

The objective of this study was to evaluate risk factors associated with eyeball loss and ambulatory vision loss on emergent examination of patients with ocular trauma. We reviewed the medical records of 1,875 patients hospitalized in a single tertiary referral center between January 2003 and December 2007. Emergent examinations included a history of trauma, elapsed time between injury and hospital arrival, visible intraocular tissues, and initial visual acuity (VA) using a penlight. The main outcome measures were ocular survival and ambulatory vision survival (>20/200) at 1 year after trauma using univariate and multivariate regression analysis. The ocular trauma scores were significantly higher in open globe injuries than in closed globe injuries (p eyeball loss. Elapsed time more than 12 hours and visible intraocular tissues were the significant risk factors associated with ambulatory vision loss. The most powerful predictor of eyeball loss and ambulatory vision loss was eyeball rupture. In closed globe injuries, there were no significant risk factors of eyeball loss, whereas initial vision less than LP and the presence of relative afferent pupillary defect were the significant risk factors associated with ambulatory vision loss. An initial VA less than LP using a penlight, a history of golf ball injury, and elapsed time more than 12 hours between ocular trauma and hospital arrival were associated with eyeball loss and ambulatory vision loss. Physicians should bear these factors in mind so that they can more effectively counsel patients with such injuries.

Magnetic resonance imaging findings as predictors of clinical outcome in patients with sciatica receiving active conservative treatment

DEFF Research Database (Denmark)

Jensen, Tue Secher; Albert, Hanne B; Sorensen, Joan S

2007-01-01

OBJECTIVE: The aims of this study were to investigate the possible prognostic value of disk-related magnetic resonance imaging (MRI) findings in relation to recovery at 14 months in patients with severe sciatica, and whether improvement of disk herniation and/or nerve root compromise is concurrent...... with recovery. METHODS: All patients included in this prospective observational study of patients with sciatica receiving active conservative treatment were scanned at baseline and at 14 months' follow-up. Definite recovery at follow-up was defined as an absence of sciatic leg pain and a Roland Morris...... in that the prevalence of disk-related MRI findings was different for men and women, and they had different recovery rates. Improvement of disk herniations and nerve root compromise over time did not coincide with definite recovery. CONCLUSIONS: In patients with sciatica receiving active conservative treatment, broad...

The New Report of Artichoke latent virus (ArLV) From Globe Artichoke in Turkey

OpenAIRE

ERKAN, Semih; GÜMÜŞ, Mustafa; DUMAN, İbrahim; PAYLAN, İsmail Can; ERGÜN, Müge

2014-01-01

n recent years, some of artichoke growers in Aegean region of Turkey stated that globe artichoke (Cynara cardunculus L. subsp. scolymus (L.) Hayek) plants in their fields have showed virus-like symptoms. So, in order to identify viruses

CONSERVATIVE TREATMENT OF BREAST CANCER, EXPERIENCE OF THE GENERAL SURGERY DEPARTMENT OF THE AVICENNE MILITARY HOSPITAL.

OpenAIRE

Mohammed Lahkim; Mohammed Es-said Ramraoui; Mohammed Jaouad Fassi Fihri; Ahmed Elguezzar; Ahmed Elkhader; Rachid El Barni; Abdessamad Achour.

2017-01-01

Breast cancer is currently the most common cancer in women, and is a major diagnostic and therapeutic problem. The radio-surgical conservatrice therapeutic management has become a standard for most tumors : stages I and II. Furthermore, the use of preoperative treatment extends the indications of conservative treatment which was initiall limited to tumors less than 3cm, unifocal, and non-inflammatory to larger tumors. Our study reports 20 patients cases of breast cancer, collected at the surg...

Using variances to comply with resource conservation and recovery act treatment standards

International Nuclear Information System (INIS)

Ranek, N.L.

2002-01-01

When a waste generated, treated, or disposed of at a site in the United States is classified as hazardous under the Resource Conservation and Recovery Act and is destined for land disposal, the waste manager responsible for that site must select an approach to comply with land disposal restrictions (LDR) treatment standards. This paper focuses on the approach of obtaining a variance from existing, applicable LDR treatment standards. It describes the types of available variances, which include (1) determination of equivalent treatment (DET); (2) treatability variance; and (3) treatment variance for contaminated soil. The process for obtaining each type of variance is also described. Data are presented showing that historically the U.S. Environmental Protection Agency (EPA) processed DET petitions within one year of their date of submission. However, a 1999 EPA policy change added public participation to the DET petition review, which may lengthen processing time in the future. Regarding site-specific treatability variances, data are presented showing an EPA processing time of between 10 and 16 months. Only one generically applicable treatability variance has been granted, which took 30 months to process. No treatment variances for contaminated soil, which were added to the federal LDR program in 1998, are identified as having been granted.

GLOBE at Night: a Worldwide Citizen-Science Program to Increase Awareness of Light Pollution by Measuring Night Sky Brightness

Science.gov (United States)

Walker, C. E.; Pompea, S. M.

2011-12-01

The emphasis in the international citizen-science, star-hunting campaign, GLOBE at Night, is in bringing awareness to the public on issues of light pollution. Light pollution threatens not only observatory sites and our "right to starlight", but can affect energy consumption, wildlife and health. GLOBE at Night has successfully reached a few 100,000 citizen-scientists. What has contributed to its success? Foundational resources are available to facilitate the public's participation in promoting dark skies awareness. The GLOBE at Night website explains clearly the simple-to-participate-in 5 step program and offers background information and interactive games on key concepts. To promote the campaign via popular social media, GLOBE at Night created Facebook and Twitter pages. The program has been expanded to include trainings of the general public, but especially educators in schools, museums and science centers, in unique ways. Education kits for dark skies awareness have been distributed at the training workshops. The kit includes material for a light shielding demonstration, a digital Sky Quality Meter and "Dark Skies Rangers" activities. The activities are on how unshielded light wastes energy, how light pollution affects wildlife and how one can participate in a citizen-science star-hunt like GLOBE at Night. To increase participation in the 2011 campaign, children and adults submitted their sky brightness measurements in real time with smart phones or tablets using the web application at www.globeatnight.org/webapp/. With smart phones and tablets, the location, date and time register automatically. For those without smart mobile devices, user-friendly tools on the GLOBE at Night report page were reconfigured to determine latitude and longitude more easily and accurately. As a proto-type for taking multiple measurements, people in Tucson found it easy to adopt a street and take measurements every mile for the length of the street. The grid of measurements

Writing education around the globe: introduction and call for a new global analysis

NARCIS (Netherlands)

Graham, S.; Rijlaarsdam, G.

This paper presents a special issue on writing around the globe. Researchers from across the world describe writing practices in their country using a wide variety of methodology. The paper show that while there are many similarities in writing instruction from one country to the next, there are

Conservative treatment of premature rectal cancer

International Nuclear Information System (INIS)

Torres, M.

2010-01-01

Objectives: The largest radical resections in rectal cancer with significant morbidity and mortality (Urinary dysfunction, sexual dysfunction, permanent colostomy, etc.), on certain occasions and with high selectivity, they can be avoided with the implementation of local resections. Our intention is to assess the results of conservative treatment of rectal cancer early. Material and Methods: Between 01.01.89 and 31.12.09 14 consecutive patients were treated carriers rectal adenocarcinoma who had never received prior cancer treatment and a second simultaneous showed no neoplasia. The age of the patients presented a range between 44 and 72 years with a mean of 60.4 years; sex similarly partitioned and according to ECOG performance status was 0≤2. All patients were operated through a anal resection of which 4 were performed a submucosal tumor excision (T1) and 10 excision was entire rectal wall and tumor invaded the muscularis propria (T2). For this one type of surgery patients were selected the following criteria: tumor ≤6 cm. the anal verge, size ≤3 cm., GH I-II, vegetative, mobile, and T1-2, N0 by EER. After intervention, the pathological examination of the surgical specimen showed that 4 patients GH III, lymphovascular invasion and / or peri neural, or close surgical margins (+) (≤3 mm.) And T3, so underwent Miles operation (March 1 T1 and T2). Subsequently the rest of the patients (10) underwent concomitant radio chemotherapy. Radiation therapy was similar all using megavoltage photons (CO-60, 18mV) to the entire pelvic volume in a normofraccionamiento to complete 50.40 Gy (1.8 Gy / 28) using multiple fields (box technique). Chemotherapy was prepared 5FU + LV in the first patient (4), in following (4) was used 5FU continuous infusion (1st and 5th week) and the remaining (2) Capecitabine. Follow up was complete. Results: In our sample we extract local failure was 4 (29%), distant failure 3 (20%) and two local and distant failures (14%) so it follows that

Isolation and mapping of a C3'H gene (CYP98A49) from globe artichoke, and its expression upon UV-C stress

NARCIS (Netherlands)

Moglia, A.; Comino, C.; Portis, E.; Acquadro, A.; Vos, de C.H.; Beekwilder, M.J.; Lanteri, S.

2009-01-01

Globe artichoke represents a natural source of phenolic compounds with dicaffeoylquinic acids along with their biosynthetic precursor chlorogenic acid (5-caffeoylquinic acid) as the predominant molecules. We report the isolation and characterization of a full-length cDNA and promoter of a globe

A study on the force balance of an unbalanced globe valve

International Nuclear Information System (INIS)

Yang, Sang Min; Cho, Taik Dong; Ko, Sung Ho; Lee, Ho Young

2007-01-01

A pneumatic control valve is a piping element that controls the volumetric flow rate and pressure of a fluid: it is necessary to analyze the characteristics of the forces with respect to the opening of the valve in order to evaluate its operating performance. The forces occurring during operation are: resisting force and actuator force, where the load resistance is mostly affected by the fluid pressure difference of the valve. In this study, a force balance equation derived from the equilibrium relationship between the resisting force and the actuator force of an unbalanced globe valve is proposed, and the force balance equations are used to model the dynamic equations of a pneumatic unbalanced globe valve installed in nuclear power plants. A CFD analysis is also carried out to evaluate the pressure distribution and forces acting on the top and bottom planes of the valve plug. The results of this analysis have been verified through experimentation. This study has shown that the fluid pressure difference between the inlet and outlet of the valve, measured from the force balance equation of an unbalanced valve, should actually be examined with the fluid-pressure difference between the top and bottom side of the valve plug

Conservative treatment of an anterior-lateral ankle dislocation without an associated fracture in a diabetic patient: a case report

Directory of Open Access Journals (Sweden)

Panagiotis K. Karampinas

2012-06-01

Full Text Available Anterior or anterior-lateral dislocation of the ankle is a rare condition that can be treated conservatively as well as any other similar types of ankle dislocations without associated fractures. We present a case report of an anterior-lateral ankle dislocation with a concomitant avulsion injury of the ankle's anterior capsule in a diabetic patient that was treated conservatively. At the patient's visit 12 months after the initial injury, he was asymptomatic with full range of motion of the ankle joint. To our knowledge, we could not identify this type of an injury in a diabetic patient that was treated successfully with conservative treatment in the existing literature.

Mitigating Mosquito Disease Vectors with Citizen Science: a Review of the GLOBE Observer Mosquito Habitat Mapper Pilot and Implications for Wide-scale Implementation

Science.gov (United States)

Riebeek Kohl, H.; Low, R.; Boger, R. A.; Schwerin, T. G.; Janney, D. W.

2017-12-01

The spread of disease vectors, including mosquitoes, is an increasingly significant global environmental issue driven by a warming climate. In 2017, the GLOBE Observer Program launched a new citizen science initiative to map mosquito habitats using the free GLOBE Observer App for smart phones and tablets. The app guides people to identify mosquito larvae and breeding sites, and then once documented, to eliminate or treat the site to prevent further breeding. It also gives citizen scientists the option to identify the mosquito larvae species to determine whether it is one of three genera that potentially could transmit Zika, dengue fever, yellow fever, chikungunya, and other diseases. This data is uploaded to an international database that is freely available to the public and science community. GLOBE Observer piloted the initiative with educators in the United States, Brazil, and Peru, and it is now open for global participation. This presentation will discuss lessons learned in the pilot phase as well as plans to implement the initiative worldwide in partnership with science museums and science centers. GLOBE Observer is the non-student citizen science arm of the Global Learning and Observations to Benefit the Environment (GLOBE) Program, a long-standing, international science and education program that provides students and citizen scientists with the opportunity to participate in data collection and the scientific process, and contribute meaningfully to our understanding of the Earth system and global environment. GLOBE Observer data collection also includes cloud cover and cloud type and land cover/land use (in late 2017).

[Second operation more frequent following breast-conserving treatment for invasive lobular than for invasive non-lobular carcinoma

NARCIS (Netherlands)

Zeeuw, S. de; Wildenberg, F.; Strobbe, L.; Wobbes, T.

2009-01-01

OBJECTIVE: To establish the frequency of re-excision or mastectomy in women who had breast-conserving treatment for invasive lobular mammary carcinoma. DESIGN: Retrospective. METHOD: Data on the number of patients with invasive carcinoma from 1998-2006 were obtained from the national pathology

Technical Challenges and Lessons from the Migration of the GLOBE Data and Information System to Utilize Cloud Computing Service

Science.gov (United States)

Moses, J. F.; Memarsadeghi, N.; Overoye, D.; Littlefield, B.

2016-12-01

The Global Learning and Observation to Benefit the Environment (GLOBE) Data and Information System supports an international science and education program with capabilities to accept local environment observations, archive, display and visualize them along with global satellite observations. Since its inception twenty years ago, the Web and database system has been upgraded periodically to accommodate the changes in technology and the steady growth of GLOBE's education community and collection of observations. Recently, near the end-of-life of the system hardware, new commercial computer platform options were explored and a decision made to utilize Cloud services. Now the GLOBE DIS has been fully deployed and maintained using Amazon Cloud services for over two years now. This paper reviews the early risks, actual challenges, and some unexpected findings as a result of the GLOBE DIS migration. We describe the plans, cost drivers and estimates, highlight adjustments that were made and suggest improvements. We present the trade studies for provisioning, for load balancing, networks, processing , storage, as well as production, staging and backup systems. We outline the migration team's skills and required level of effort for transition, and resulting changes in the overall maintenance and operations activities. Examples include incremental adjustments to processing capacity and frequency of backups, and efforts previously expended on hardware maintenance that were refocused onto application-specific enhancements.

Technical Challenges and Lessons from the Migration of the GLOBE Data and Information System to Utilize Cloud Computing Service

Science.gov (United States)

Moses, John F.; Memarsadeghi, Nargess; Overoye, David; Littlefield, Brain

2017-01-01

The Global Learning and Observation to Benefit the Environment (GLOBE) Data and Information System supports an international science and education program with capabilities to accept local environment observations, archive, display and visualize them along with global satellite observations. Since its inception twenty years ago, the Web and database system has been upgraded periodically to accommodate the changes in technology and the steady growth of GLOBEs education community and collection of observations. Recently, near the end-of-life of the system hardware, new commercial computer platform options were explored and a decision made to utilize Cloud services. Now the GLOBE DIS has been fully deployed and maintained using Amazon Cloud services for over two years now. This paper reviews the early risks, actual challenges, and some unexpected findings as a result of the GLOBE DIS migration. We describe the plans, cost drivers and estimates, highlight adjustments that were made and suggest improvements. We present the trade studies for provisioning, for load balancing, networks, processing, storage, as well as production, staging and backup systems. We outline the migration teams skills and required level of effort for transition, and resulting changes in the overall maintenance and operations activities. Examples include incremental adjustments to processing capacity and frequency of backups, and efforts previously expended on hardware maintenance that were refocused onto application-specific enhancements.

Understanding structural conservation through materials science:

DEFF Research Database (Denmark)

Fuster-López, Laura; Krarup Andersen, Cecil

2014-01-01

with tools to avoid future problems, it should be present in all conservation-restoration training programs to help promote students’ understanding of the degradation mechanisms in cultural materials (and their correlation with chemical and biological degradation) as well as the implications behind......Mechanical properties and the structure of materials are key elements in understanding how structural interventions in conservation treatments affect cultural heritage objects. In this context, engineering mechanics can help determine the strength and stability found in art objects as it can...... provide both explanation and prediction of failure in materials. It has therefore shown to be an effective method for developing useful solutions to conservation problems. Since materials science and mechanics can help conservators predict the long term consequences of their treatments and provide them...

CineGlobe Film Festival, Wednesday programme with Science Story Telling Hackathon and Oculus Rift

CERN Multimedia

Marcelloni De Oliveira, Claudia

2015-01-01

Besides the short-film competitions, the second day of 2015 CineGlobe included a Soirée Oculus Rift with the public launch of the “Storytelling Science” Hackathon. CineGlobe and Festival Tous Ecrans joined forces to launch the “Storytelling Science” hackathon, in collaboration with Tribeca Film Institute and LIFT Conference. The keynote speech was given by renowned filmmaker and transmedia creator Michel Reihlac, who spoke about the role of interactive and immersive storytelling techniques in cinematic narrative. By placing the viewer in the center of the story, these new technologies are profoundly changing the way we tell stories. Michel Reilhac designs innovative story based experiences, using digital platforms (cinema, tv, mobile, tablets, …) and real life events. His creative approach to storytelling ambitions to offer viewers/ participants a unique opportunity for an immersive, participatory and interactive experience. During the evening, Oculus Rift virtual reality headsets were available to...

Terminology - glossary including acronyms and quotations in use for the conservative spinal deformities treatment: 8th SOSORT consensus paper.

Science.gov (United States)

Grivas, Theodoros B; de Mauroy, Jean Claude; Négrini, Stefano; Kotwicki, Tomasz; Zaina, Fabio; Wynne, James H; Stokes, Ian A; Knott, Patrick; Pizzetti, Paolo; Rigo, Manuel; Villagrasa, Monica; Weiss, Hans Rudolf; Maruyama, Toru

2010-11-02

This report is the SOSORT Consensus Paper on Terminology for use in the treatment of conservative spinal deformities. Figures are provided and relevant literature is cited where appropriate. The Delphi method was used to reach a preliminary consensus before the meeting, where the terms that still needed further clarification were discussed. A final agreement was found for all the terms, which now constitute the base of this glossary. New terms will be added after being discussed and accepted. When only one set of terms is used for communication in a place or among a group of people, then everyone can clearly and efficiently communicate. This principle applies for any professional group. Until now, no common set of terms was available in the field of the conservative treatment of scoliosis and spinal deformities. This glossary gives a common base language to draw from to discuss data, findings and treatment.

Spaceflight-Induced Visual Impairment and Globe Deformations in Astronauts Are Linked to Orbital Cerebrospinal Fluid Volume Increase.

Science.gov (United States)

Alperin, Noam; Bagci, Ahmet M

2018-01-01

Most of the astronauts onboard the International Space Station (ISS) develop visual impairment and ocular structural changes that are not fully reversible upon return to earth. Current understanding assumes that the so-called visual impairments/intracranial pressure (VIIP) syndrome is caused by cephalad vascular fluid shift. This study assesses the roles of cerebrospinal fluid (CSF) and intracranial pressure (ICP) in VIIP. Seventeen astronauts, 9 who flew a short-duration mission on the space shuttle (14.1 days [SD 1.6]) and 7 who flew a long-duration mission on the ISS (188 days [SD 22]) underwent MRI of the brain and orbits to assess the pre-to-post spaceflight changes in four categories: VIIP severity measures: globe flattening and nerve protrusion; orbital and ventricular CSF volumes; cortical gray and white matter volumes; and MR-derived ICP (MRICP). Significant pre-to-post-flight increase in globe flattening and optic nerve protrusion occurred only in the long-duration cohort (0.031 [SD 0.019] vs -0.001 [SD 0.006], and 0.025 [SD 0.013] vs 0.001 [SD 0.006]; p < 0.00002 respectively). The increased globe deformations were associated with significant increases in orbital and ventricular CSF volumes, but not with increased tissue vascular fluid content. Additionally, a moderate increase in MRICP of 6 mmHg was observed in only two ISS astronauts with large ocular structure changes. These findings are evidence for the primary role of CSF and a lesser role for intracranial cephalad fluid-shift in the formation of VIIP. VIIP is caused by a prolonged increase in orbital CSF spaces that compress the globes' posterior pole, even without a large increase in ICP.

12 CFR 360.6 - Treatment by the Federal Deposit Insurance Corporation as conservator or receiver of financial...

Science.gov (United States)

2010-01-01

... accepted accounting principles, other than the “legal isolation” condition as it applies to institutions... the conditions for sale accounting treatment set forth by generally accepted accounting principles in... Corporation as conservator or receiver of financial assets transferred in connection with a securitization or...

Effect of adjuvant systemic treatment on cosmetic outcome and late normal-tissue reactions after breast conservation

International Nuclear Information System (INIS)

Johansen, Joergen; Overgaard, Jens; Overgaard, Marie

2007-01-01

To investigate whether adjuvant treatment with CMF or tamoxifen predisposes to an unfavorable cosmetic outcome or increased breast morbidity after radiotherapy in breast conservation. Data from 266 patients who entered a randomized breast conservation trial (DBCG-82TM protocol) was analyzed. The patients were treated with lumpectomy and axillary dissection followed by external beam radiotherapy to the residual breast. High-risk patients (n 94), as well as 31 low-risk patients, received additional radiation to the regional lymph nodes. Adjuvant systemic treatment was given to all high-risk patients: premenopausal patients (n = 67) received eight cycles of CMF intravenously (600/40/600 mg/m 2 ) every fourth week; postmenopausal patients (n = 27) received 30 mg of tamoxifen daily for one year. Clinical assessments included cosmetic outcome, breast fibrosis, skin telangiectasia, and dyspigmentation which were scored on a 4-point categorical scale after median 6.6 years. The observations were analyzed in multivariate logistic regression analysis which included potential risk factors on outcome related to systemic treatment, surgery, radiation technique, tumor, and patient characteristics. In premenopausal patients, systemic treatment with CMF independently predicted a fair/poor cosmetic outcome, RR = 2.2 (95% CI 1.2-4.2), as well as increased skin telangiectasia, RR = 3.3 (1.4-8.2). There was no impact of tamoxifen treatment on cosmetic outcome in postmenopausal patients (p 0.32). However, univariate analysis showed that tamoxifen was significantly associated with breast fibrosis (p <0.004), as was radiation to the regional lymph nodes (p <0.0001). A strong interaction between axillary irradiation and tamoxifen treatment occurred since 26 of 27 high-risk postmenopausal patients had received both tamoxifen and axillary irradiation. In multivariate regression analysis, axillary irradiation independently predicted moderate/severe breast fibrosis with a relative risk of 5

Public outreach: les spectacles du Globe

CERN Document Server

2006-01-01

Shows at the Globe of Science and Innovation in connection with the exhibition «A des années-lumière» Wednesday 8 November 2006, 2.30 p.m. (in French): 'Cooking with the stars' Professor BEUZ and his assistant Mr POZZONI, a clown double-act, will introduce children to the cosmos, the formation of the universe and the creation of stars and the solar system. On the menu: eggs, biscuits, a 'comet' sausage, giant onions, noodles, 'primordial' soup, instant pudding, fruit and vegetables. A spicy and scholarly recipe that will satisfy little gourmets and budding astronomers alike. This event is a version of the comedy 'How to make the Universe' specially adapted for children. For young children (7 years and upwards) Free admittance, by reservation only: + 41(0)22 767 76 76 Thursday 9 and Friday 10 November 2006, 8.00 p.m. (in French): 'How to make the Universe' At the end of a meal, Professor BEUZ and his assistant Mr POZZONI tell us the story of how the universe was formed, from the Big Bang to the arriv...

Around the Globe with Buzz Aldrin

CERN Multimedia

Katarina Anthony

2011-01-01

Buzz Aldrin! The news caused a sensation: his arrival was imminent. The man who, 40 years ago, first step foot on the moon, was to do the same at CERN.   Buzz Aldrin dumps the pilot beams from the LHC. Visiting the Globe on 1 March to endorse General Motors’ (GM) new ecological programme, Buzz Aldrin took advantage of the occasion to take a whistle-stop tour of the Organisation. “CERN is dealing with things going very fast underground; I’m dealing with things going fast – not that fast though! – up in orbit,” he said. Accompanied by his wife Lois and singer Katie Melua - also invited by GM to perform at the private event - Buzz began his visit with a short introduction to CERN at the Universe of Particles exhibit. He then met with Andrzej Siemko, group leader of the LHC machine protection, at the SM-18 super conducting magnet test facility. The astronaut’s last stop was at the CCC, where the LHC team had somethi...

Globe : Fête de la science 2007

CERN Multimedia

2007-01-01

FROM 8 TO 13 OCTOBER 2007 Globe of Science and Innovation - Route de Meyrin, 1211 Geneva >>> "Expo NANO. Technology takes on a new dimension". Open on the Monday, Tuesday, Thursday and Friday from 2.00 p.m. to 5.30 p.m. and on the Wednesday and Saturday from 10.00 a.m. to 5.30 p.m. >>> Conference/Debate on the LHC "The LHC: an accelerator of science". Thursday 11 October from 8.00 p.m. to 10 p.m. CERN will soon commission the world’s most powerful accelerator, the LHC. This machine, the latest and greatest in a long line of CERN accelerators, is designed to provide answers to the remaining unsolved mysteries surrounding the building blocks of matter. Speakers : Jean-Philippe Tock, Jean-Pierre Revol, Daniel Denegri, Richard Jacobsson and Laurent Chevalier Free entrance. Please book by calling + 41 (0)22 767 76 76 >>> "Poussière d’étoiles" workshop: Saturday 13 October from 10 a.m. to 5.30 p.m. The "Poussière d’étoiles...

The Costa Rica GLOBE (Global Learning and Observations to Benefit the Environment) Project as a Learning Science Environment

Science.gov (United States)

Castro Rojas, María Dolores; Zuñiga, Ana Lourdes Acuña; Ugalde, Emmanuel Fonseca

2015-12-01

GLOBE is a global educational program for elementary and high school levels, and its main purpose in Costa Rica is to develop scientific thinking and interest for science in high school students through hydrology research projects that allow them to relate science with environmental issues in their communities. Youth between 12 and 17 years old from public schools participate in science clubs outside of their regular school schedule. A comparison study was performed between different groups, in order to assess GLOBE's applicability as a learning science atmosphere and the motivation and interest it generates in students toward science. Internationally applied scales were used as tools for measuring such indicators, adapted to the Costa Rican context. The results provide evidence statistically significant that the students perceive the GLOBE atmosphere as an enriched environment for science learning in comparison with the traditional science class. Moreover, students feel more confident, motivated and interested in science than their peers who do not participate in the project. However, the results were not statistically significant in this last respect.

IDP camp evolvement analysis in Darfur using VHSR optical satellite image time series and scientific visualization on virtual globes

Science.gov (United States)

Tiede, Dirk; Lang, Stefan

2010-11-01

In this paper we focus on the application of transferable, object-based image analysis algorithms for dwelling extraction in a camp for internally displaced people (IDP) in Darfur, Sudan along with innovative means for scientific visualisation of the results. Three very high spatial resolution satellite images (QuickBird: 2002, 2004, 2008) were used for: (1) extracting different types of dwellings and (2) calculating and visualizing added-value products such as dwelling density and camp structure. The results were visualized on virtual globes (Google Earth and ArcGIS Explorer) revealing the analysis results (analytical 3D views,) transformed into the third dimension (z-value). Data formats depend on virtual globe software including KML/KMZ (keyhole mark-up language) and ESRI 3D shapefiles streamed as ArcGIS Server-based globe service. In addition, means for improving overall performance of automated dwelling structures using grid computing techniques are discussed using examples from a similar study.

Percutaneous vertebroplasty compared to conservative treatment in patients with painful acute or subacute osteoporotic vertebral fractures.Three months follow up in a clinical randomised study

DEFF Research Database (Denmark)

Rousing, Rikke

2008-01-01

with a few exceptions. We observed 2 adjacent fractures in the PVP group and non in the conservative group. Conclusion. The majority of patients with acute or subacute painful osteoporotic compression fractures in the spine will recover after a few months of conservative treatment. The risk of adjacent......Abstract Study design. Clinical randomised study.    Objective. The aim of this study is to compare PVP to conservative treatment of patients with osteoporotic vertebral fractures in a clinical randomised study with respect to pain, physical and mental outcome, and to asses the risk of adjacent......) were included from January 2001 until January 2008. Patients with acute (treatment. Pain was assessed with a visual analogue scale and physical and mental outcome were...

Hamlet's "Globe" and the Self as Performer in England and Japan

OpenAIRE

Shibuya, Yu

2004-01-01

In his paper, "Hamlet's 'Globe' and the Self as Performer in England and Japan," Yu Shibuya argues that Hamlet sees his life as a performance. Shibuya presents examples from Tsuneari Fukuda's Japanese translation to suggest that Fukuda makes choices that emphasize the theatrical side of Hamlet's character. If Hamlet perceives himself as an actor, then his definition of theater or an actor is ultimately a definition of himself. Shibuya uses the theme of self-definition to examine Kenneth Brana...

Minerals profile of two globe artichoke cultivars as affected by NPK fertilizer regimes.

Science.gov (United States)

Lombardo, Sara; Pandino, Gaetano; Mauromicale, Giovanni

2017-10-01

Globe artichoke is a proven source of various minerals (such as K, Fe and Zn) in the Mediterranean diet, but their content in response to fertilizer regime has not yet been investigated sufficiently. Thus, we monitored the effect of two contrasting nitrogen/phosphorus/potassium (NPK) fertilizer regimes (one balanced and the other excessive) on the minerals accumulation of 'Apollo' and 'Tema 2000' cultivars, grown in three Sicilian locations ('Landolina', 'Iannarello' and 'Zotto') - South Italy. Except for total nitrogen, the balanced fertilizer regime favoured the accumulation of both macro- and micro-minerals, but with a different extent depending especially on trial location. Particularly, plants grown at 'Iannarello' responded more strongly to the fertilizer regime with respect to K, P, Ca, Fe and Zn accumulation, as a result of its different soil characteristics than the other locations. Providing a balanced supply of nitrogen/phosphorus/potassium via fertilization can enhance the nutritive value of globe artichoke, but taking into account especially soil characteristics. Copyright © 2017 Elsevier Ltd. All rights reserved.

Globe Event | Lecture by Hervé Dessimoz and Thomas Büchi | 14 May

CERN Document Server

Globe Info

2013-01-01

At the summit of Sustainable Development, by Hervé Dessimoz and Thomas Büchi.   Globe de la science et de l'innovation Route de Meyrin, 1211 Genève Tuesday 14 May 2013 at 8:30 p.m. The lecture will be in French Refuge du Goûter. Hervé Dessimoz and Thomas Büchi have been committed to sustainable development since the 2000s. They created the Palais de l’Équilibre at Expo.02. They designed an exhibition in conjunction with the Cité de la Science et de l’Industrie (Paris) to educate visitors about sustainable development. The pavilion was donated to CERN by the Swiss Confederation and rebuilt on the CERN site in 2004. It is now known as the Globe of Science and Innovation. The Refuge du Goûter, on the slopes of Mont Blanc, is the culmination of their research into sustainable development, with the aim of demonstrating that if we can construct a building at 3835 m which is a...

Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH: study protocol for a randomized controlled trial

Directory of Open Access Journals (Sweden)

Zan Xin

2012-06-01

Full Text Available Abstract Background Spontaneous intracerebral hemorrhage is a disease with high morbidity, high disability rate, high mortality, and high economic burden. Whether patients can benefit from surgical evacuation of hematomas is still controversial, especially for those with moderate-volume hematomas in the basal ganglia. This study is designed to compare the efficacy of endoscopic surgery and conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage. Methods Patients meet the criteria will be randomized into the endoscopic surgery group (endoscopic surgery for hematoma evacuation and the best medical treatment or the conservative treatment group (the best medical treatment. Patients will be followed up at 1, 3, and 6 months after initial treatment. The primary outcomes include the Extended Glasgow Outcome Scale and the Modified Rankin Scale. The secondary outcomes consist of the National Institutes of Health Stroke Scale and the mortality. The Barthel Index(BI will also be evaluated. The sample size is 100 patients. Discussion The ECMOH trial is a randomized controlled trial designed to evaluate if endoscopic surgery is better than conservative treatment for patients with moderate-volume hematomas in the basal ganglia. Trial registration Chinese Clinical Trial Registry: ChiCTR-TRC-11001614 (http://www.chictr.org/en/proj/show.aspx?proj=1618

GIS-project: geodynamic globe for global monitoring of geological processes

Science.gov (United States)

Ryakhovsky, V.; Rundquist, D.; Gatinsky, Yu.; Chesalova, E.

2003-04-01

A multilayer geodynamic globe at the scale 1:10,000,000 was created at the end of the nineties in the GIS Center of the Vernadsky Museum. A special soft-and-hardware complex was elaborated for its visualization with a set of multitarget object directed databases. The globe includes separate thematic covers represented by digital sets of spatial geological, geochemical, and geophysical information (maps, schemes, profiles, stratigraphic columns, arranged databases etc.). At present the largest databases included in the globe program are connected with petrochemical and isotopic data on magmatic rocks of the World Ocean and with the large and supperlarge mineral deposits. Software by the Environmental Scientific Research Institute (ESRI), USA as well as ArcScan vectrorizator were used for covers digitizing and database adaptation (ARC/INFO 7.0, 8.0). All layers of the geoinformational project were obtained by scanning of separate objects and their transfer to the real geographic co-ordinates of an equiintermediate conic projection. Then the covers were projected on plane degree-system geographic co-ordinates. Some attributive databases were formed for each thematic layer, and in the last stage all covers were combined into the single information system. Separate digital covers represent mathematical descriptions of geological objects and relations between them, such as Earth's altimetry, active fault systems, seismicity etc. Some grounds of the cartographic generalization were taken into consideration in time of covers compilation with projection and co-ordinate systems precisely answered a given scale. The globe allows us to carry out in the interactive regime the formation of coordinated with each other object-oriented databases and thematic covers directly connected with them. They can be spread for all the Earth and the near-Earth space, and for the most well known parts of divergent and convergent boundaries of the lithosphere plates. Such covers and time series

[Acute inpatient conservative multimodal treatment of complex and multifactorial orthopedic diseases in the ANOA concept].

Science.gov (United States)

Psczolla, M

2013-10-01

In Germany there is a clear deficit in the non-operative treatment of chronic and complex diseases and pain disorders in acute care hospitals. Only about 20 % of the treatments are carried out in orthopedic hospitals. Hospitals specialized in manual medicine have therefore formed a working group on non-operative orthopedic manual medicine acute care clinics (ANOA). The ANOA has developed a multimodal assessment procedure called the OPS 8-977 which describes the structure and process quality of multimodal and interdisciplinary diagnosis and treatment of the musculoskeletal system. Patients are treated according to clinical pathways oriented on the clinical findings. The increased duration of treatment in the German diagnosis-related groups (DRG) system is compensated for with a supplemental remuneration. Thus, complex and multifactorial orthopedic diseases and pain disorders are conservatively and appropriately treated as inpatient departments of acute care hospitals.

Terminology - glossary including acronyms and quotations in use for the conservative spinal deformities treatment: 8th SOSORT consensus paper

Directory of Open Access Journals (Sweden)

Pizzetti Paolo

2010-11-01

Full Text Available Abstract Background This report is the SOSORT Consensus Paper on Terminology for use in the treatment of conservative spinal deformities. Figures are provided and relevant literature is cited where appropriate. Methods The Delphi method was used to reach a preliminary consensus before the meeting, where the terms that still needed further clarification were discussed. Results A final agreement was found for all the terms, which now constitute the base of this glossary. New terms will be added after being discussed and accepted. Discussion When only one set of terms is used for communication in a place or among a group of people, then everyone can clearly and efficiently communicate. This principle applies for any professional group. Until now, no common set of terms was available in the field of the conservative treatment of scoliosis and spinal deformities. This glossary gives a common base language to draw from to discuss data, findings and treatment.

Conservative Management of Central Cemento-Ossifying Fibroma.

Science.gov (United States)

Gomes-Ferreira, Pedro Henrique Silva; Carrasco, Leandro Carlos; de Oliveira, Danila; Pereira, Járede Carvalho; Alcalde, Luis Fernando Azambuja; Faverani, Leonardo Perez

2017-01-01

Central cemento-ossifying fibroma is characterized by the combined production of osteoid and cementoid tissue. Radiographically, this lesion is presented as an outlined cortical and variable radiopaque spots, also can be present complete radiolucent or different degrees of radiopacity. The recommended treatment is curettage or enucleation, and the recurrence rate is less than 5%. Considering that surgical treatment is invasive, mainly in large lesions, this study aims to report a patient in whom conservative treatment was carried out by involving the preservation of teeth, with a long-term follow-up. A 48-year-old black female patient, diagnosed with central cemento-ossifying fibroma in mandible, treated conservatively and a 2 years of follow-up. It was concluded that the conservative treatment with a long term of follow-up for maintaining teeth was satisfactory.

Conservative therapeutic management of carpal tunnel syndrome

Directory of Open Access Journals (Sweden)

Roberto Sérgio Martins

Full Text Available ABSTRACT Carpal tunnel syndrome is the most prevalent nerve compression and can be clinically or surgically treated. In most cases, the first therapeutic alternative is conservative treatment but there is still much controversy regarding the most effective modality of this treatment. In this study, we critically evaluated the options of conservative treatment for carpal tunnel syndrome, aiming to guide the reader through the conventional options used in this therapy.

The effectiveness of surgical versus conservative treatment for symptomatic unilateral spondylolysis of the lumbar spine in athletes: a systematic review.

Science.gov (United States)

Scheepers, Morné Stephan; Streak Gomersall, Judith; Munn, Zachary

2015-04-17

Spondylolysis is a common cause of low back pain in athletes. Historically, spondylolysis injuries were thought to be mostly bilateral; however advances in lumbar spine imaging have shown that in certain athlete groups, unilateral spondylolysis is highly prevalent. It remains unclear whether athletes with unilateral spondylolysis who undergo surgical repair are able to return to sports as effectively or faster than if they had conservative treatment. To determine the effectiveness of surgical fixation performed after a trial period of conservative management, compared to the effectiveness of conservative management only for unilateral spondylolysis in athletes.   Athletes with symptomatic unilateral spondylolysis of the lumbar spine.  Types of intervention(s):  Surgical interventions which attempted a direct repair of the pars interarticularis, compared to conservative management.  Types of studies:  Experimental and epidemiological study designs were considered for inclusion. The majority of the studies reviewed consisted of descriptive epidemiological study designs including case series, individual case reports and descriptive cross sectional studies.  Types of outcomes:  The primary outcome of interest in this review was the ability to return to sport. The effectiveness of surgery on pain and overall function were secondary outcomes of interest. A three-step search strategy that aimed to find both published and unpublished studies was utilized. The search was limited to studies published in the English language between 1 January 1970 and 1 September 2013. The studies were critically appraised using one of the standardized critical appraisal instruments from The Joanna Briggs Institute. Details describing each study and results on effectiveness in promoting the outcomes of interest were extracted from papers included in the review using the standardized data extraction tool from The Joanna Briggs Institute. Due to heterogeneity in the included studies, the

[S3 guideline. Part 2: Non-Traumatic Avascular Femoral Head Necrosis in Adults - Untreated Course and Conservative Treatment].

Science.gov (United States)

Roth, A; Beckmann, J; Smolenski, U; Fischer, A; Jäger, M; Tingart, M; Rader, C; Peters, K M; Reppenhagen, S; Nöth, U; Heiss, C; Maus, U

2015-10-01

In Germany there are 5000 to 7000 new cases of atraumatic avascular necrosis of the femoral head in adults per year. It occurs mostly in middle age. An increased frequency of idiopathic cases can be observed. Chemotherapy, corticoids and kidney transplants are frequently associated with the disease. In most cases the disease occurs on both sides. Early diagnosis is of particular importance, since in early stages it is most likely to avoid late damage with joint destruction. Whereas previously the temporary operational joint preservation and subsequent joint replacement were often the only option of treatment, conservative and joint-preserving measures today play an increasing role. After the AWMF guidelines for S3 guideline clinical questions were formulated. Over the period from 01/01/1970 to 31/05/2013 a literature search was conducted. Systematic reviews, metaanalyses, original papers and clinical trials of all designs were evaluated. There were a total of 3715 references, of which 422 for the assessment regarding SIGN were eligible and finally 180 were in accord with the defined inclusion and exclusion criteria. For the untreated course and the assessment of conservative measures, a total of 42 references was suitable. In formulating the recommendations the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) system was used, which distinguishes A "shall", B "should" and 0 "can". If left untreated, the aFKN within 2 years leads to a subchondral fracture and subsequent collapse. After the diagnosis of femoral head necrosis, the risk of a disease of the opposite side is high within the next 2 years, then unlikely. The sole conservative treatment brings no benefit for the treatment of atraumatic avascular necrosis in the adult. Although it improves function, less pain can be obtained, and surgical intervention can be delayed, the progression is not stopped. Conservative treatment must therefore always be part of the overall treatment. In ARCO

The Capabilities Approach: Fostering contexts for enhancing mental health and wellbeing across the globe.

Science.gov (United States)

White, Ross G; Imperiale, Maria Grazia; Perera, Em

2016-05-05

Concerted efforts have been made in recent years to achieve equity and equality in mental health for all people across the globe. This has led to the emergence of Global Mental Health as an area of study and practice. The momentum that this has created has contributed to the development, implementation and evaluation of services for priority mental disorders in many low- and middle-income countries.This paper discusses two related issues that may be serving to limit the success of mental health initiatives across the globe, and proposes potential solutions to these issues. First, there has been a lack of sophistication in determining what constitutes a 'good outcome' for people experiencing mental health difficulties. Even though health is defined and understood as a state of 'wellbeing' and not merely an absence of illness, mental health interventions tend to narrowly focus on reducing symptoms of mental illness. The need to also focus more broadly on enhancing subjective wellbeing is highlighted. The second limitation relates to the lack of an overarching theoretical framework guiding efforts to reduce inequalities and inequities in mental health across the globe. This paper discusses the potential impact that the Capabilities Approach (CA) could have for addressing both of these issues. As a framework for human development, the CA places emphasis on promoting wellbeing through enabling people to realise their capabilities and engage in behaviours that they subjectively value. The utilization of the CA to guide the development and implementation of mental health interventions can help Global Mental Health initiatives to identify sources of social inequality and structural violence that may impede freedom and individuals' opportunities to realise their capabilities.

Sensor Webs and Virtual Globes: Enabling Understanding of Changes in a partially Glaciated Watershed

Science.gov (United States)

Heavner, M.; Fatland, D. R.; Habermann, M.; Berner, L.; Hood, E.; Connor, C.; Galbraith, J.; Knuth, E.; O'Brien, W.

2008-12-01

The University of Alaska Southeast is currently implementing a sensor web identified as the SouthEast Alaska MOnitoring Network for Science, Telecommunications, Education, and Research (SEAMONSTER). SEAMONSTER is operating in the partially glaciated Mendenhall and Lemon Creek Watersheds, in the Juneau area, on the margins of the Juneau Icefield. These watersheds are studied for both 1. long term monitoring of changes, and 2. detection and analysis of transient events (such as glacier lake outburst floods). The heterogeneous sensors (meteorologic, dual frequency GPS, water quality, lake level, etc), power and bandwidth constraints, and competing time scales of interest require autonomous reactivity of the sensor web. They also present challenges for operational management of the sensor web. The harsh conditions on the glaciers provide additional operating constraints. The tight integration of the sensor web and virtual global enabling technology enhance the project in multiple ways. We are utilizing virtual globe infrastructures to enhance both sensor web management and data access. SEAMONSTER utilizes virtual globes for education and public outreach, sensor web management, data dissemination, and enabling collaboration. Using a PosgreSQL with GIS extensions database coupled to the Open Geospatial Consortium (OGC) Geoserver, we generate near-real-time auto-updating geobrowser files of the data in multiple OGC standard formats (e.g KML, WCS). Additionally, embedding wiki pages in this database allows the development of a geospatially aware wiki describing the projects for better public outreach and education. In this presentation we will describe how we have implemented these technologies to date, the lessons learned, and our efforts towards greater OGC standard implementation. A major focus will be on demonstrating how geobrowsers and virtual globes have made this project possible.

Introducing a New Elementary GLOBE Book on Climate: Supporting Educators and Students in their Understanding of the Concepts Underlying Climate and Climate Change

Science.gov (United States)

Stanitski, D.; Hatheway, B.; Gardiner, L. S.; Taylor, J.; Chambers, L. H.

2016-12-01

Much of the focus on climate literacy in K-12 occurs in middle and high school, where teachers and students can dig into the science in some depth. It is important, however, to introduce this topic at an early age, building on a child's natural curiosity about the world around them - but without overwhelming them with frightening climate change impacts. In some U.S. school systems, a recent focus on standardized testing has crowded out science instruction in order to bring up literacy scores. To give teachers a resource to maintain some science instruction under these conditions, a series of Elementary GLOBE books have been developed. These fictional stories describe sound science and engineering practices that are essential for students to learn the process of science while expanding literacy skills, strongly encouraged in the Next Generation Science Standards (NGSS). The main concepts developed in a new Elementary GLOBE book on climate, titled "What in the World Is Happening to Our Climate?", will be introduced in this presentation. This book complements six other Earth System Science modules within the Elementary GLOBE curriculum and is freely available on the GLOBE website (www.globe.gov/elementaryglobe). The book discusses the concept that climate is changing in different ways and places around the world, and what happens to the climate in one place affects other locations across the globe. Supporting ideas clarify the difference between weather and climate, introduce climate science concepts, reveal the impacts of sea level rise, and help students understand that, while humans are contributing to climate change, they can also participate in solutions that address this challenge. Accompanying teacher's notes and companion classroom activities will be described to help elementary school teachers understand how to approach the subject of climate change with their students.

[Systematic review on conservative treatment options in non-muscle-invasive bladder cancer patients refractory to Bacillus Calmette-Guérin instillation therapy].

Science.gov (United States)

Martini, Thomas; Wezel, Felix; Löbig, Niklas; Mitterberger, Michael J; Colleselli, Daniela

2017-08-01

Background Adjuvant Bacillus Calmette-Guérin (BCG) intravesical instillation is the recommended standard treatment in patients with high-risk non-muscle-invasive bladder cancer (NMIBC). However, a significant proportion of patients fail treatment, and radical cystectomy (RC) is the subsequent gold standard. On the other hand, there is an unmet need for conservative alternatives for patients who are unfit or unwilling to undergo surgery. This study aimed to identify conservative treatment options in NMIBC patients after BCG failure. Material and Methods We performed a systematic search in the databases Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and EMBASE, including all randomised controlled trials (RCTs), quasi-RCTs and single-arm studies, in which patients with NMIBC were treated with second-line intravesical or systemic therapy after BCG failure. A minimum of eight patients were included in each treatment arm. Full papers were restricted to English language. Literature research and data analysis were assessed independently by two reviewers. Data on treatment response, recurrence, time to recurrence, progression and rate of cystectomy were collected and analysed. Results  This systematic review included 42 publications with a total of 3521 patients (2371 BCG failures). Valrubicin, taxanes, gemcitabine, combination chemotherapy, thermochemotherapy, photodynamic therapy, combination of BCG and interferon and immunotherapies or targeted therapies were identified as conservative treatment options. For taxanes, gemcitabine and thermochemotherapy there is the highest evidence for a clinical meaningful response with minor toxicities. Conclusions Despite some promising response rates for taxanes, gemcitabine or thermochemotherapy, an evidence-based recommendation for treatment options superior to RC in patients failing BCG therapy cannot be made. The definition of BCG failure is still inconsistent and heterogeneous outcomes in patients with BCG

Physikshow is a hit in the Globe

CERN Multimedia

CERN Bulletin

2010-01-01

Students from the University of Bonn put on three highly successful performances of their "Physikshow", a theatrical journey into the world of particles.   All you need is a bit of imagination and stage management for even the most abstract of physics to become entertaining and intelligible, a principle demonstrated by 20 students from the University of Bonn and their teachers who gave three performances of their "Physikshow" in the Globe of Science and Innovation. The students quickly won over their audience using an array of amazing experiments and wacky sketches to illustrate the world of particles, the principle of forces and the evolution of the cosmos. More than 370 pupils from local secondary schools in France and the Cantons of Geneva and Vaud travelled to CERN for the two performances specially reserved for schools. The audience for the public performance numbered no fewer than 250. Physikshow was first performed in 2002 and has evolved over the years th...

Conservative approach to rectosigmoid endometriosis: a cohort study.

Science.gov (United States)

Egekvist, Anne G; Marinovskij, Edvard; Forman, Axel; Kesmodel, Ulrik S; Riiskjaer, Mads; Seyer-Hansen, Mikkel

2017-06-01

The aim of the study was to assess the risk of surgery after initial conservative treatment of rectosigmoid endometriosis in relation to demographic data. The study was conducted on the tertiary endometriosis referral unit, Aarhus University Hospital. Medical records, from patients seen from January 2009 onwards with a diagnosis of rectosigmoid endometriosis and more than 6 months' follow up were audited. Demographic data, results of magnetic resonance imaging and time to secondary surgery for rectosigmoid endometriosis were registered. Data on 238 patients diagnosed with rectosigmoid endometriosis were included. In all, 78 (32.8%) patients had primary surgery, 27 (11.3%) had secondary surgery and 133 (55.9%) continued conservative treatment throughout the observation period. Patients who underwent primary or secondary surgery were younger than patients continuing conservative treatment. In a tertiary referral center where about half of patients with rectosigmoid endometriosis were scheduled for conservative treatment, more than 80% of these avoided surgery. © 2017 Nordic Federation of Societies of Obstetrics and Gynecology.

Partial breast irradiation as second conservative treatment for local breast cancer recurrence

International Nuclear Information System (INIS)

Hannoun-Levi, Jean-Michel; Houvenaeghel, Gilles; Ellis, Steve; Teissier, Eric; Alzieu, Claude; Lallement, Michel; Cowen, Didier

2004-01-01

Purpose: Mastectomy is the treatment of reference for local relapse after breast cancer (BC). The aim of this study was to document the feasibility and the results of associating lumpectomy with partial breast irradiation by interstitial brachytherapy (IB) as local treatment for an isolated ipsilateral BC local recurrence (LR). Methods and materials: Between 1975 and 1996 at Marseille and Nice Cancer Institutes, 4026 patients received lumpectomy and radiotherapy (RT) (50-80 Gy) for a localized breast cancer of which 473 presented a LR. Among these patients, 69 (14.6%) received a second lumpectomy followed by IB, which delivered 30 Gy (Nice, n = 24) or 45-50 Gy (Marseille, n = 45) with 3 to 8 192 Ir wires in 1 or 2 planes on the 85% isodose. Results: Median age at LR was 58.2 years, median follow-up since primary BC was 10 years, and median follow-up after the second conservative treatment was 50.2 months (range, 2-139 months). Immediate tolerance was good in all cases. Grade 2 to 3 long-term complications (LTC) according to IB dose were 0%, 28%, and 32%, respectively, for 30 Gy, 45 to 46 Gy, and 50 Gy (p 0.01). Grade 2 to 3 LTC according to total dose were 4% and 30%, respectively, for total doses (initial RT plus IB) ≤ 100 Gy or >100 Gy (p = 0.008). Logistic regression showed that the only factor associated with Grade 2 to 3 complications was higher IB doses (p = 0.01). We noted 11 second LRs (LR2), 10 distant metastases (DM), and 5 specific deaths. LR2 occurred either in the tumor bed (50.8%) or close to the tumor bed (34.3%) or in another quadrant (14.9%). Kaplan-Meier 5-year freedom from (FF) LR2 (FFLR2), FFDM, and DFS were 77.4%, 86.7%, and 68.9%, respectively. Overall 5-year survival (OS) was 91.8%. Univariate analysis showed the following factors associated with a higher FFLR2: (1) number of wires used for IB (3-4 vs. 5-8 wires, p = 0.006), (2) IB doses (30-45 Gy vs. 46-60 Gy, p = 0.05), (3) number of planes (1 vs. 2, p = 0.05), (4) interval between

Management of extra-capsular temporo-mandibular joint ankylosis: does conservative approach to treatment have a role?

Science.gov (United States)

Anyanechi, C E; Osunde, O D; Bassey, G O

2015-06-01

The conventional management of fibrous extracapsular temporo-mandibular joint (TMJ) ankylosis, a debilitating disease, is associated with surgical complications and financial burden on the patients. To assess the outcome of conservative approach to the management of fibrous extracapsular TMJ ankylosis. This is a prospective study of patients who presented at the Dental and Maxillofacial Surgery Clinic of the University of Calabar Teaching Hospital, Nigeria, during the period from January 1999 to December 2012 with a history of inability to open the mouth diagnosed as fibrous extracapsular TMJ ankylosis. Twenty-one subjects were treated and their ages ranged from 11 to 22 years with mean at 15.0 years. There were 13 (61.9 %) males and 8 (38.1 %) females with male: female ratio of 1.6:1. The aetiological factor that predisposed to formation of extracapsular TMJ ankylosis was facial trauma. There was no facial asymmetry and the side distribution of the affliction showed that 1 (4.8 %) was bilateral while 20 (95.2 %) were unilateral. Eight cases (38.1 %) were incomplete ankylosis while the rest (n = 13, 61.9 %) were complete. The shorter the duration of fibrous ankylosis and the greater the initial inter-incisal distance before treatment, the better the treatment outcome. The outcome of treatment suggests that the conservative approach to management of this condition was beneficial to these patients because they presented early. However, randomized controlled clinical trials are needed to validate this treatment option.

Analysis gives the penal treatment in Cuba to the tied infractions to the use and conservation gives radioactive substances

International Nuclear Information System (INIS)

Perez Gonzalez, F.; Perez Velazquez, R.S.; Fornet, R.O.; Reyes Fajardo, E.

1998-01-01

The work refers the realized analysis to the Law 62 the Cuban penal code that with establishing to the treatment of the infractions referred standard's to the uses and conservation the radioactive substances and other ionizing radiations sources

Time Use and Physical Activity: A Shift Away from Movement across the Globe

Science.gov (United States)

Ng, Shu Wen; Popkin, Barry

2012-01-01

Technology linked with reduced physical activity (PA) in occupational work, home/domestic work, and travel and increased sedentary activities, especially television viewing, dominates the globe. Using detailed historical data on time allocation, occupational distributions, energy expenditures data by activity, and time-varying measures of metabolic equivalents of task (MET) for activities when available, we measure historical and current MET by four major PA domains (occupation, home production, travel, and active leisure) and sedentary time among adults (> 18 years). Trends by domain for the United States (1965–2009), the United Kingdom (1961–2005), Brazil (2002–2007), China (1991–2009), and India (2000–2005) are presented. We also project changes in energy expenditure by domain and sedentary time (excluding sleep and personal care) to 2020 and 2030 for each of these countries. The use of previously unexplored detailed time allocation and energy expenditures and other datasets represents a useful addition to our ability to document activity and inactivity globally. Given the potential impact on weight gain and other cardiometabolic health risks, the differential declines in MET of activity and increases in sedentary time across the globe represents a major threat to global health. PMID:22694051

Conservation Documentation and the Implications of Digitisation

Directory of Open Access Journals (Sweden)

Michelle Moore

2001-11-01

Full Text Available Conservation documentation can be defined as the textual and visual records collected during the care and treatment of an object. It can include records of the object's condition, any treatment done to the object, any observations or conclusions made by the conservator as well as details on the object's past and present environment. The form of documentation is not universally agreed upon nor has it always been considered an important aspect of the conservation profession. Good documentation tells the complete story of an object thus far and should provide as much information as possible for the future researcher, curator, or conservator. The conservation profession will benefit from digitising its documentation using software such as databases and hardware like digital cameras and scanners. Digital technology will make conservation documentation more easily accessible, cost/time efficient, and will increase consistency and accuracy of the recorded data, and reduce physical storage space requirements. The major drawback to digitising conservation records is maintaining access to the information for the future; the notorious pace of technological change has serious implications for retrieving data from any machine- readable medium.

First detailed karyo-morphological analysis and molecular cytological study of leafy cardoon and globe artichoke, two multi-use Asteraceae crops

Directory of Open Access Journals (Sweden)

Debora Giorgi

2016-09-01

Full Text Available Traditionally globe artichoke and leafy cardoon have been cultivated for use as vegetables but these crops are now finding multiple new roles in applications ranging from paper production to cheese preparation and biofuel use, with interest in their functional food potential. So far, their chromosome complements have been poorly investigated and a well-defined karyotype was not available. In this paper, a detailed karyo-morphological analysis and molecular cytogenetic studies were conducted on globe artichoke (Cynara cardunculus Linnaeus, 1753 var. scolymus Fiori, 1904 and leafy cardoon (C. cardunculus Linneaus, 1753 var. altilis De Candolle, 1838. Fluorescent In Situ Hybridization In Suspension (FISHIS was applied to nuclei suspensions as a fast method for screening of labelling probes, before metaphase spread hybridization. Classic Fluorescent In Situ Hybridization (FISH on slide, using repetitive telomeric and ribosomal sequences and Simple Sequence Repeats (SSRs oligonucleotide as probes, identified homologous chromosome relationships and allowed development of molecular karyotypes for both varieties. The close phylogenetic relationship between globe artichoke and cardoon was supported by the very similar karyotypes but clear chromosomal structural variation was detected. In the light of the recent release of the globe artichoke genome sequencing, these results are relevant for future anchoring of the pseudomolecule sequence assemblies to specific chromosomes. In addition, the DNA content of the two crops has been determined by flow cytometry and a fast method for standard FISH on slide and methodological improvements for nuclei isolation are described.

Engaging Citizen Scientists across North America to Monitor Eclipse-driven Environmental Change through NASA GLOBE Observer, Results and Lessons Learned

Science.gov (United States)

Riebeek Kohl, H.; Weaver, K.; Overoye, D.; Martin, A.; Andersen, T.

2017-12-01

How cool was the eclipse? NASA GLOBE Observer challenged citizen scientists across North America to answer that question by observing temperature and cloud changes throughout the August 2017 Total Solar Eclipse. The experiment was meant to chart the impact of changes in solar energy at Earth's surface across all regions that experienced the eclipse, both partial and total. Citizen scientists reported air temperature every 5-10 minutes from first contact to last contact through the free GLOBE Observer app. They also reported cloud cover and cloud type every 15-30 minutes or as changes happened as a proxy for changes in the atmosphere. No data were collected during totality, as we wanted citizen scientists to focus on the eclipse at that time. To recruit citizen scientists, members of the GLOBE Observer Team participated in six large outreach events across the path of totality. We also encouraged participation outside the path of totality though partnerships with informal education institutions and direct communication to the public through NASA communication channels. This presentation will report statistics on citizen science participation and lessons learned about citizen science as an outreach tool. Did participation in the experiment enhance a person's eclipse experience? Did citizen scientists find enough value in the experiment to continue to participate in GLOBE Observer, a long-term citizen science program, after the eclipse? We will also present early results of observed temperature and cloud changes.

Radiotherapy effect in conservation treatment for breast cancer

International Nuclear Information System (INIS)

Sachini, V.; Ferreri, A.J.M.; Farante, G.; Agresti, R.; Galimberti, V.; Zurrida, S.; Veronesi, P.

1994-01-01

Radiotherapy (RT) in conservative treatment for breast cancer (CT-BC) has been proven to be determinant for the local control of the disease. Radiation therapy was described by several authors as the most important factor affecting the cosmetic results of this treatment. Technical progress in RT, use of filters and wedges and an increased knowledge of the influence of fraction size total dose and irradiated volume on breast tissues contributed to avoid major radiotherapeutic side effects in the CT-BC. Cosmetic outcome from 2 groups of patients (pts) with breast cancer in stage T 1-2(T> = 2,5 cm) N 0-1 M o0 of the prospective trial Milan III were compared. Both groups pts (n=89) were treated with quadrantectomyand axillary dissection. 49 pts received complementary RT with a dose of 50 Gy over 5 weeks with a daily fraction of 2 Gy and a further boost of 10 Gy (10 MeV electrons) on the scar. Remaining 40 pts did not receive RT. Cosmetic results were subjectively and objectively (asymmetry index) evaluated. No significant cosmetic differences were observed between the 2 study groups. A good or excellent symmetry was observed in 59% of irradiated pts and 64% of non irradiated pts. Negative results were observed in 4% and 2% respectively. Subjective ovulation showed similar results, with a good or excellent symmetry in 57% of irradiated pts and 72.5% of non irradiated pts. Poor results were observed in 16.3% and 27.5% respectively. Telangiectasia were observed in 4% of irradiated pts, while hypertrophied scars were only noted in non irradiated pts (15%). No acute side effects of RT, as erythema or ulceration of breast skin, were recorded. In our experience, the standard dose of 50 Gy administered by two opposite tangential fields plus a 10 Gy boost did not affect the cosmetic results of CT.BC, whereas it provided a better local control of disease. The possibility to avoid RT in selected group of pts should be justified by the discomfort of this treatment for the pt, cost

Radiotherapy for squamous cell carcinoma of maxillary sinus. Requirements for conservative treatment strategy

International Nuclear Information System (INIS)

Onishi, Hiroshi; Komiyama, Takafumi; Marino, Kan; Kuriyama, Kengo; Tanaka, Shiho; Araki, Tsutomu; Sano, Naoki

2004-01-01

We reviewed the records of 45 patients with squamous cell carcinoma of maxillary sinus who underwent radiotherapy and intra-arterial chemotherapy with or without maxillectomy. Of 45 patients, 10 patients (stage II:III:IV A=1:5:4) were operated with radical radiotherapy without maxillectomy and had no local failure for more than 1 year (conservative and no local failure group), and 9 patients (stage III:IV A=3:6) were performed with partial or total maxillectomy after pre-operative radiotherapy and had no malignant cells in the operated specimen (group B). Complete response on radiological images was shown in 70% of patients in group A, and 67% of patients in group B. In group A, local recurrence was found in 1 of 10 patients in group A and 1 of 9 patients in group B during a further follow-up period. Five-year overall survival rate was 53% and 67% in group A and B, respectively. Five-year cause-specific survival rate was 89% and 67% in group A and B, respectively. Maxillary conservative treatment is appropriate in cases showing good response on radiological images after radiotherapy combined with concurrent intra-arterial infusion chemotherapy. (author)

Genome-Wide Identification of BAHD Acyltransferases and In vivo Characterization of HQT-like Enzymes Involved in Caffeoylquinic Acid Synthesis in Globe Artichoke

Science.gov (United States)

Moglia, Andrea; Acquadro, Alberto; Eljounaidi, Kaouthar; Milani, Anna M.; Cagliero, Cecilia; Rubiolo, Patrizia; Genre, Andrea; Cankar, Katarina; Beekwilder, Jules; Comino, Cinzia

2016-01-01

Globe artichoke (Cynara cardunculus L. var. scolymus) is a rich source of compounds promoting human health (phytonutrients), among them caffeoylquinic acids (CQAs), mainly represented by chlorogenic acid (CGA), and dicaffeoylquinic acids (diCQAs). The enzymes involved in their biosynthesis belong to the large family of BAHD acyltransferases. Following a survey of the globe artichoke genome, we identified 69 BAHD proteins carrying the catalytic site (HXXXD). Their phylogenetic analysis together with another 43 proteins, from 21 species, representative of the BAHD family, highlighted their grouping in seven major clades. Nine globe artichoke acyltransferases clustered in a sub-group of Clade V, with 3 belonging to hydroxycinnamoyl-CoA:quinate hydroxycinnamoyl transferase (HQT) and 2 to hydroxycinnamoyl-CoA:shikimate/quinate hydroxycinnamoyl transferase (HCT) like proteins. We focused our attention on the former, HQT1, HQT2, and HQT3, as they are known to play a key role in CGA biosynthesis. The expression of genes coding for the three HQTs and correlation of expression with the CQA content is reported for different globe artichoke tissues. For the first time in the globe artichoke, we developed and applied the virus-induced gene silencing approach with the goal of assessing in vivo the effect of HQT1 silencing, which resulted in a marked reduction of both CGA and diCQAs. On the other hand, when the role of the three HQTs was assessed in leaves of Nicotiana benthamiana through their transient overexpression, significant increases in mono- and diCQAs content were observed. Using transient GFP fusion proteins expressed in N. benthamiana leaves we also established the sub-cellular localization of these three enzymes. PMID:27721818

Eyeball Position in Facial Approximation: Accuracy of Methods for Predicting Globe Positioning in Lateral View.

Science.gov (United States)

Zednikova Mala, Pavla; Veleminska, Jana

2018-01-01

This study measured the accuracy of traditional and validated newly proposed methods for globe positioning in lateral view. Eighty lateral head cephalograms of adult subjects from Central Europe were taken, and the actual and predicted dimensions were compared. The anteroposterior eyeball position was estimated as the most accurate method based on the proportion of the orbital height (SEE = 1.9 mm) and was followed by the "tangent to the iris method" showing SEE = 2.4 mm. The traditional "tangent to the cornea method" underestimated the eyeball projection by SEE = 5.8 mm. Concerning the superoinferior eyeball position, the results showed a deviation from a central to a more superior position by 0.3 mm, on average, and the traditional method of central positioning of the globe could not be rejected as inaccurate (SEE = 0.3 mm). Based on regression analyzes or proportionality of the orbital height, the SEE = 2.1 mm. © 2017 American Academy of Forensic Sciences.

An Optimization Method for Virtual Globe Ocean Surface Dynamic Visualization

Directory of Open Access Journals (Sweden)

HUANG Wumeng

2016-12-01

Full Text Available The existing visualization method in the virtual globe mainly uses the projection grid to organize the ocean grid. This special grid organization has the defects in reflecting the difference characteristics of different ocean areas. The method of global ocean visualization based on global discrete grid can make up the defect of the projection grid method by matching with the discrete space of the virtual globe, so it is more suitable for the virtual ocean surface simulation application.But the available global discrete grids method has many problems which limiting its application such as the low efficiency of rendering and loading, the need of repairing grid crevices. To this point, we propose an optimization for the global discrete grids method. At first, a GPU-oriented multi-scale grid model of ocean surface which develops on the foundation of global discrete grids was designed to organize and manage the ocean surface grids. Then, in order to achieve the wind-drive wave dynamic rendering, this paper proposes a dynamic wave rendering method based on the multi-scale ocean surface grid model to support real-time wind field updating. At the same time, considering the effect of repairing grid crevices on the system efficiency, this paper presents an efficient method for repairing ocean surface grid crevices based on the characteristics of ocean grid and GPU technology. At last, the feasibility and validity of the method are verified by the comparison experiment. The experimental results show that the proposed method is efficient, stable and fast, and can compensate for the lack of function of the existing methods, so the application range is more extensive.

Is Mastectomy Superior to Breast-Conserving Treatment for Young Women?

International Nuclear Information System (INIS)

Coulombe, Genevieve; Tyldesley, Scott; Speers, Caroline B.A.; Paltiel, Chuck M.Sc.; Aquino-Parsons, Christina; Bernstein, Vanessa; Truong, Pauline T.; Keyes, Mira; Olivotto, Ivo A.

2007-01-01

Purpose: To examine whether modified radical mastectomy (MRM) improves outcomes compared with breast-conserving treatment (BCT) in young women. Methods and Materials: Women aged 20-49 years, diagnosed with early breast cancer between 1989 and 1998, were identified. Management with BCT or MRM was compared for local (L), locoregional (LR), and distant relapse-free survival (DRFS) and breast cancer-specific survival (BCSS) by age group (20-39 years, 40-49 years). The analysis was repeated for patients considered 'ideal' candidates for BCT: tumor size ≤2 cm, pathologically negative axillary nodes, negative margins, and no reported ductal carcinoma in situ. Results: A total of 1,597 women received BCT, and 801 had MRM. After a median follow-up of 9.0 years, the outcomes (L, LR, BCSS) were worse for the younger age group; however, the outcomes were not statistically different by type of local treatment. For women aged 20-39 years considered 'ideal' for BCT, those treated with BCT had slightly lower LRFS compared with those treated with MRM (p = 0.3), but DRFS and BCSS were similar. Conclusions: A difference in LRFS at 10 years potentially favored MRM among women aged 20-39 years considered 'ideal' BCT candidates but was not statistically significant and did not translate into a noticeable difference in DRFS or BCSS. Our data suggest that young age alone is not a contraindication to BCT

Proposal for the award of a contract for the wood construction work for the Globe of Innovation project

CERN Document Server

2003-01-01

This document concerns the award of a contract for the wood construction work for the Globe of Innovation project. A call for tenders (IT-3260/ST/GIR) was sent on 31 October 2003 to twelve firms in one Member State. By the closing date, CERN had received five tenders from four firms and one consortium. The Finance Committee is invited to agree to the negotiation of a contract with CIB (CH), the lowest bidder, for the wood construction work for the Globe of Innovation project for an estimated amount not exceeding 820 000 Swiss francs, not subject to revision. The firm has indicated the following distribution by country of the contract value covered by this adjudication proposal: CH - 100%.

Treatment morbidity associated with the management of the axilla in breast-conserving therapy

International Nuclear Information System (INIS)

Johansen, J.; Overgaard, J.; Blichert-Toft, M.; Overgaard, M.

2000-01-01

The purpose of this study was to determine the impact of surgery and radiotherapy on late morbidity associated with the management of the axilla in breast cancer patients. Two hundred and sixty-six patients from a randomized breast conservation trial (DBCG-82TM protocol) were called in for a single follow-up interview and clinical examination of several functional outcome measures after a median of 6.6 years (3.5-10.5). All the patients were treated with lumpectomy and axillary dissection, followed by external beam radiotherapy to the residual breast. High-risk patients were given additional radiation to the regional lymph nodes plus adjuvant systemic treatment. Twenty-eight patients (11%) had arm edema (> or 2 cm), which was associated with the extent of axillary node dissection as well as with age and radiotherapy (relative risk, RR 4.5 (1.8-11.2, p = 0.001)). Impaired shoulder movement of any degree (7%) was associated with radiotherapy (RR 4.0 (1.5-13.8, p = 0.007)) and advanced age (p = 0.002), while the extent of axillary dissection as described by the number of nodes retrieved was the only factor that predicted pain on logistic regression analysis (p = 0.02). A moderate to severe change in arm/shoulder strength and working ability was observed in 7% and 5% of patients, respectively, but no independent predisposing factor was discerned for these endpoints. It is concluded that the level of late functional morbidity several years after breast-conserving treatment is relatively low and clearly relates to age, extension of surgery, irradiation of the axilla or a combination of these factors, depending on the specific clinical outcome measure

Biodiversity, Life History, and Conservation of Northeastern Pacific Chondrichthyans.

Science.gov (United States)

Ebert, David A; Bigman, Jennifer S; Lawson, Julia M

The sharks, batoids, and chimaeras, collectively the class Chondrichthyes, are one of the most successful groups of fishes, with over 1250 species globally. Recent taxonomic revisions have increased their diversity by about 20% over the past 17 years (2000-2016). The Northeast Pacific Ocean is one of the top 20 most diverse regions/countries on the globe with 77 chondrichthyan species, a number less than a quarter that of the most species-rich area (Australia) but that has increased by 10% since 2000 to include three new species (two skates and a chimaera). In this chapter we discuss the species richness of chondrichthyans occurring in the Northeast Pacific Ocean, characterize their life histories, briefly review several fisheries, and summarize the conservation status of those chondrichthyans occurring in the region. Detailed descriptions and evaluations of fisheries can be found in Chapter 7 of AMB Volume 78. © 2017 Elsevier Ltd. All rights reserved.

Local Treatment for Monochrome Outdoor Painted Metal Sculptures: Assessing the suitability of conservation paints for retouching

OpenAIRE

van Basten, Nikki; Defeyt, Catherine; Rivenc, Rachel

2015-01-01

When outdoor painted sculptures get chipped, scratched or abraded, conservators might consider local retouching treatments as an option that would protect the exposed metal substrate and restore the aesthetic integrity, thus postponing a very costly and invasive overall repainting. Unfortunately, matching colour gloss and texture on large monochrome surfaces is always challenging. This paper reports on research undertaken to investigate some of the materials and application techniques that co...

Using Digital Globes to Explore the Deep Sea and Advance Public Literacy in Earth System Science

Science.gov (United States)

Beaulieu, S. E.; Brickley, A.; Emery, M.; Spargo, A.; Patterson, K.; Joyce, K.; Silva, T.; Madin, K.

2014-12-01

Digital globes are new technologies increasingly used in both informal and formal education to display global datasets. By creating a narrative using multiple datasets, linkages between Earth systems - lithosphere, hydrosphere, atmosphere, and biosphere - can be conveyed. But how effective are digital globes in advancing public literacy in Earth system science? We addressed this question in developing new content for digital globes that interweaves imagery obtained by deep-diving vehicles with global datasets, including a new dataset locating the world's known hydrothermal vents. Our two narratives, "Life Without Sunlight" (LWS) and "Smoke and Fire Underwater" (SFU), each focus on STEM (science, technology, engineering, and mathematics) principles related to geology, biology, and exploration. We are preparing a summative evaluation for our content delivered on NOAA's Science on a Sphere as interactive presentations and as movies. We tested knowledge gained with respect to the STEM principles and the level of excitement generated by the virtual deep-sea exploration. We conducted a Post-test Only Design with quantitative data based on self-reporting on a Likert scale. A total of 75 adults and 48 youths responded to our questionnaire, distributed into test groups that saw either one of the two narratives delivered either as a movie or as an interactive presentation. Here, we report preliminary results for the youths, the majority (81%) of which live in towns with lower income and lower levels of educational attainment as compared to other towns in Massachusetts. For both narratives, there was knowledge gained for all 6 STEM principles and "Quite a Bit" of excitement. The mode in responses for knowledge gained was "Quite a Bit" for both the movie and the interactive presentation for 4 of the STEM principles (LWS geology, LWS biology, SFU geology, and SFU exploration) and "Some" for SFU biology. Only for LWS exploration was there a difference in mode between the

Ten-year results of treatment of ductal carcinoma in situ (DCIS) of the breast with conservative surgery and radiotherapy.

Science.gov (United States)

Amichetti, M; Caffo, O; Richetti, A; Zini, G; Rigon, A; Antonello, M; Arcicasa, M; Coghetto, F; Valdagni, R; Maluta, S; Di Marco, A

1997-09-01

The optimal treatment of ductal carcinoma in situ (DCIS) of the breast has not yet been established. The effectiveness of adjuvant postoperative radiotherapy after conservative surgery is debated. Few data are available in Italy on the combined treatment. A collaborative multi-institutional study on this issue in 10 radiation oncology departments of the north-east of Italy was conducted. One hundred and thirty nine women with DCIS of the breast were treated between 1980 and 1990. Age ranged between 28 and 88 years (median 50 years). Surgical procedures were: quadrantectomy in 108, lumpectomy in 22 and wide excision in 9 cases. The axilla was surgically staged in 97 cases: all the patients were node-negative. Radiation therapy was delivered with 60Co units (78%) or 6 MV linear accelerators (22%) for a median total dose to the entire breast of 50 Gy (mean 49.48 Gy; range 45-60 Gy). The tumour bed was boosted in 109 cases (78%) at a dose of 4-30 Gy (median 10 Gy) for a minimum tumour dose of 58 Gy. Median follow-up was 81 months. Thirteen local recurrences were recorded, 7 intraductal and 6 invasive. All recurrent patients had a salvage mastectomy and are alive and free of disease. Actuarial overall, cause-specific and recurrence-free survival at 10 years are of 93%, 100% and 86%, respectively. The results of this retrospective multicentric study substantiate the favourable data reported in the literature and confirm the efficacy of the breast-conserving treatment of DCIS employing conservative surgery and adjuvant radiation therapy.

Diagnostyka i leczenie zachowawcze łokcia tenisisty = Diagnosis and conservative treatment of tennis elbow

Directory of Open Access Journals (Sweden)

Gustaw Wójcik

2017-02-01

  Introduction. Tennis elbow is a relatively common disorder of the musculoskeletal system, for which effective treatment strategy is still unknown. It is responsible for considerable pain and loss of function of the affected limb. Characteristic for the diseases are degenerative changes in the structure of collagen and abnormalities in blood supply associated with the process of neovascularization. Pathology is due to cycles of repetitive stress leading to tissue damage. The sensitivity of imaging depends on the duration of the disease. The first period of the disease is usually caused by trauma, which may be accompanied by inflammation, which is why the most effective treatment may be anti-inflammatory therapy and immobilization of a limb. The subsequent period  is connected with degenerative changes, and treatment relies mainly on combating the painful symptoms. Conditions refractory to conservative treatment are eligible for surgery. The objective of the study. Presentation of current knowledge about diagnosis and treatment of enthesopathy of the lateral epicondyle of the humerus. Materials and method. The work is based on a review of literature of Baz PubMed, Scopus and Web of Science. Conclusions. The primary imaging technique for the diagnosis of tennis elbow is ultrasound. Classic radiology is rather used for the differentiation of other diseases related to the elbow. Modern methods of treatment of tennis elbow are based on the treatment of degenerative changes. Anti-inflammatory treatment is ineffective in the above disease.

Thursday Programme of CineGlobe Festival 2015

CERN Multimedia

Cugini, Pavel

2015-01-01

The CineGlobe Programme on Thursday 26th March 2015 counted with two short-films inspired by science sessions, two workshops on the 360 degree dome, and a special evening show in collaboration with the Mapping Festival, to celebrate the UNESCO Year of Light. The evening open with Diego Blas, CERN theorist, talking about Light, Einstein and the LHC to celebrate the UNESCO International Year of Light. Followed by a performance by the artist YRO_EILE_18. The artist Yro presents Eile, a live installation performance where light, sound, and cinema converge to tell a timeless story. EILE is a live cinema performance, in which yro makes live sound and images with a camera, some microphones and small objects like stones, balls, bits of paper and string.These materials allow him to create videos and sound, which aesthetics are close to abstract cinema and object theater assembled, sampled and grinded . The process is part of the staging itself as well as the film that results. Indescribable Eile is lived as an experie...

Events at the Globe of Science and Innovation

CERN Multimedia

2006-01-01

CERN is organising a series of lectures based on the exhibition À des années lumière... Thursday 7 December, 8.00 p.m. (in French) 'A look at Einstein and physics from the different perspectives of a physicist and an illustrator' John Ellis, CERN physicist, and Fiami, author of the comic book 'The Lives of Einstein' Come and explore physics with a comic book author who will present six vital episodes in the history of knowledge in the company of his hero, Albert Einstein. After this literary voyage of discovery, a CERN physicist will explain the issues facing physics today, more than a century after Einstein's miracle year. There will be a book signing session with Fiami at the end of the talk www.fiami.ch Lecture for the general public By reservation only: + 41 (0)22 767 76 76 Information on future meetings : www.cern.ch/globe

Use of GLOBE Observations to Derive a Landsat 8 Split Window Algorithm for Urban Heat Island

Science.gov (United States)

Fagerstrom, L.; Czajkowski, K. P.

2017-12-01

Surface temperature has been studied to investigate the warming of urban climates, also known as urban heat islands, which can impact urban planning, public health, pollution levels, and energy consumption. However, the full potential of remotely sensed images is limited when analyzing land surface temperature due to the daunting task of correcting for atmospheric effects. Landsat 8 has two thermal infrared sensors. With two bands in the infrared region, a split window algorithm (SWA), can be applied to correct for atmospheric effects. This project used in situ surface temperature measurements from NASA's ground observation program, the Global Learning and Observations to Benefit the Environment (GLOBE), to derive the correcting coefficients for use in the SWA. The GLOBE database provided land surface temperature data that coincided with Landsat 8 overpasses. The land surface temperature derived from Landsat 8 SWA can be used to analyze for urban heat island effect.

Local Recurrences After Conservative Treatment of Ductal Carcinoma-In-Situ of the Breast Without Radiotherapy: The Effect of Age

NARCIS (Netherlands)

Schouten van der Velden, A.P.; Peeters, P.H.M.; Koot, V.C.M.; Hennipman, A.

2006-01-01

Background: The main goal in treatment of ductal carcinoma-in-situ (DCIS) of the breast is to prevent local recurrences. Radiotherapy after breast-conserving surgery has been shown to decrease the recurrence rate, although whether all patients should be treated with radiotherapy remains a topic

Evaluation of patients submitted to the arthroscopic treatment of the lateral epicondylitis refractory to the conservative treatment

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Fabio Alexandre Martynetz

2013-12-01

Full Text Available Objective: to evaluate the results of the arthroscopic treatment of the lateral epicondylitis. Methods: we evaluated 14 patients (15 elbows submitted to the arthroscopic treatment of the lateral epicondylitis refractory to the conservative treatment, which was realized for a minimum period of 18 months. Beyond the demographic data collection, patients were evaluated according to the arthroscopic classification of Baker et al., the Disabilities of the Arm, Shoulder, and Hand (DASH questionnaire and the Mayo Elbow Performance Score (MEPS. The patients' ages ranged between 23 and 56 years (average 46 years (eight males and six females. Of the 15 elbows, 12 were the dominant and one patient had bilateral lesion. The follow-up after surgery was minimum 24 months and maximum 72 months (average 41 months. Results: we found, according to the arthroscopic classification of Baker et al., two patients with type I lesions, nine with type II lesions and three with type III lesions. We found the following complications: one patient with altered sensitivity in the region of the lateral portal, one with a deficit of ten degrees in length, one with synovial plica and one with synovitis in the lateral compartment. Our score on the DASH questionnaire was minimum of 32 points and maximum of 120 points (average 57 points and the scale of MEPS had a minimum score of 60 points and a maximum of 100 points (average 90 points. Conclusion: the arthroscopic treatment of the lateral epicondylitis, plus insurance, provides satisfactory results.

A prospective randomized study of conservative versus surgical treatment of unstable palmar plate disruption in the proximal interphalangeal finger joint

DEFF Research Database (Denmark)

Werlinrud, Jens Christian; Petersen, Kirstin; Lauritsen, Jens

2013-01-01

study in which 83 patients were randomly assigned into 2 groups: (1) conservative treatment with a rigid splint for 2 weeks, (2) surgical reattachment of the palmar plate in local anesthesia followed by 2 weeks of immobilization in a plaster cast. Both groups were thereafter treated by taping...... to the neighboring finger for 3 weeks. With regard to hyperextension instability, stiffness, and pain, there is no significant difference in outcome between patients with traumatic palmar plate lesions and hyperextension instability treated with surgical repair and patients treated conservatively with a splint. We...

Data and interpretation: enhancing conservation of art and cultural heritage through collaboration between scientist, conservator, and art historian

International Nuclear Information System (INIS)

Huang, Jo-Fan

2012-01-01

Conservation practices can be greatly enhanced and influenced by scientific analysis and art historical insights. In the same respect, scientific data can be contextualized and substantiated by findings from visual examination and historical research. Such collaboration can contribute to the field of conservation in multiple ways: by assisting the conservator to investigate treatment options, discover artists' materials and techniques, determine date of manufacture, and investigate conservation treatment materials. Several technical studies conducted by the author and her collaborators employed micro-x-ray fluorescence (μ-XRF), Raman Spectroscopy, Fourier-transform infrared spectrometry (FTIR), and scanning electron microscopy with energy dispersive x-ray spectroscopy (SEM-EDS) and polarized light microscopy (PLM). These techniques were used on the following previously published projects such as a Japanese painting at the Museum of Fine Arts at Boston, Thai manuscripts at the Arthur M. Sackler Museum at Harvard University, and Chinese export paintings on pith at the Winterthur Museum. Although these studies have been published in the past, they are worthy examples to illustrate how collaborations between conservator, scientist, and art historian complement one another. This presentation will also touch upon ethics in sampling of fine art materials and several online databases such as Infrared and Raman User Group (IRUG) and Conservation and Art Materials Encyclopedia Online (CAMEO), which have proven to be very helpful in the field of conservation.

Features rehabilitation of infants with congenital hip dislocation on the stages of conservative treatment

Directory of Open Access Journals (Sweden)

Sergei Yurievich Voloshin

2015-06-01

Full Text Available Congenital dislocation of the hip is one of the most common diseases in children leading to disability, which is difficult to diagnose in the first days of life. In the structure of congenital orthopedic diseases congenital dislocation of the hip holds one of the first places. This determines the importance and urgency of the problem, as the most complete restoration of anatomical structures and functions of the hip joint in children occurs in the early diagnosis and comprehensive, timely begun treatment. Rehabilitation of children in the first year of life should be early, systematic, comprehensive and differentiated. Technique of rehabilitation stages conservative treatment includes: wearing functional tires, gymnastics, massage, physiotherapy, therapeutic swimming. This prevents the progression of the disease, the development of early and late complications, does not violate the static-dynamic functions without delay verticalization.

Le Palais de l'Equilibre se mue en Globe de l'Innovation le canton pourrait aussi financer son aménagement sur la route de Meyrin

CERN Multimedia

Jan-Hess, Isabel

2003-01-01

Plans for the new Globe of Innovation have finally been agreed. It will be sited opposite the entrance to CERN along with a second building for conferences and meetings. The Globe will be used for welcoming visitors. The Geneva Canton could also finance its installation in Meyrin (2 pages)

Parity non-conservation in atoms

International Nuclear Information System (INIS)

Barkov, L.M.

1982-01-01

The parity non-conservation discovered in particle physics in 1959 has consequences on the behaviour of atoms illuminated by light of circular polarization. The theoretical treatments of this topic and recent experimental test of detecting the effects of parity non-conservation on atomic physics are listed, reviewed and illustrated. The main experimental results and limits are summarized. Proposed future experiments are discussed. (D.Gy.)

Breast conservation treatment of early stage breast cancer: patterns of failure

Energy Technology Data Exchange (ETDEWEB)

Leborgne, Felix; Leborgne, Jose H; Ortega, Bettys; Doldan, Raquel; Zubizarreta, Eduardo

1995-02-15

Purpose: This study retrospectively assesses the patterns of failure in conservatively treated early stage breast cancer patients by correlating various clinical, pathologic, and treatment-related factors with local, axillary, and distant relapse. Methods and Materials: Between 1973 and 1990, 796 patients (817 breasts) received breast conservation surgery followed by radiotherapy. Local recurrences were counted as events even if they occurred simultaneously or after the appearance of axillary or distant metastases. Results: The 10-year actuarial relative disease-free survival (DFS) rate for T1N0, T2N0, and T1-2N1 was 82%, 71%, and 54%, respectively. Stage N0 patients had a significant DFS advantage over N1 patients (p = 0.02). The 15-year actuarial local recurrence-free rate for T1 and T2 tumors was 82% and 87%, respectively (p = nonsignificant). Univariate analysis identified three significant risk factors for local relapse: (a) 48 breasts with tumors showing an extensive intraductal component had a crude local recurrence rate of 23% compared to 8% for 769 breasts without intraductal component (p 0.0016); (b) the actuarial 10-year local recurrence-free rate for patients under age 40 years was 64% compared to 88% for patients over 40 years (p < 0.0001); (c) the 10-year actuarial local recurrence-free rate for 416 postmenopausal women without adjuvant tamoxifen was 83% compared to 97% for 107 postmenopausal women with tamoxifen (p = 0.0479). Salvage therapy for operable local recurrent patients resulted in a 8-year actuarial DFS rate of 47%, significantly lower than that obtained with primary treatment. The incidence of axillary relapse as the first sign of recurrence was 2%, and could be correlated with the lack of axillary dissection (p < 0.0000005) and primary tumor size (p = 0.03). Radiotherapy to the axilla did not influence axillary relapse. Actuarial 5-year DFS rate after treatment of isolated axillary recurrence was 27%. Axillary failure was a marker for

Breast conservation treatment of early stage breast cancer: patterns of failure

International Nuclear Information System (INIS)

Leborgne, Felix; Leborgne, Jose H.; Ortega, Bettys; Doldan, Raquel; Zubizarreta, Eduardo

1995-01-01

Purpose: This study retrospectively assesses the patterns of failure in conservatively treated early stage breast cancer patients by correlating various clinical, pathologic, and treatment-related factors with local, axillary, and distant relapse. Methods and Materials: Between 1973 and 1990, 796 patients (817 breasts) received breast conservation surgery followed by radiotherapy. Local recurrences were counted as events even if they occurred simultaneously or after the appearance of axillary or distant metastases. Results: The 10-year actuarial relative disease-free survival (DFS) rate for T1N0, T2N0, and T1-2N1 was 82%, 71%, and 54%, respectively. Stage N0 patients had a significant DFS advantage over N1 patients (p = 0.02). The 15-year actuarial local recurrence-free rate for T1 and T2 tumors was 82% and 87%, respectively (p = nonsignificant). Univariate analysis identified three significant risk factors for local relapse: (a) 48 breasts with tumors showing an extensive intraductal component had a crude local recurrence rate of 23% compared to 8% for 769 breasts without intraductal component (p 0.0016); (b) the actuarial 10-year local recurrence-free rate for patients under age 40 years was 64% compared to 88% for patients over 40 years (p < 0.0001); (c) the 10-year actuarial local recurrence-free rate for 416 postmenopausal women without adjuvant tamoxifen was 83% compared to 97% for 107 postmenopausal women with tamoxifen (p = 0.0479). Salvage therapy for operable local recurrent patients resulted in a 8-year actuarial DFS rate of 47%, significantly lower than that obtained with primary treatment. The incidence of axillary relapse as the first sign of recurrence was 2%, and could be correlated with the lack of axillary dissection (p < 0.0000005) and primary tumor size (p = 0.03). Radiotherapy to the axilla did not influence axillary relapse. Actuarial 5-year DFS rate after treatment of isolated axillary recurrence was 27%. Axillary failure was a marker for

Planned caesarean in the interventional radiology cath lab to enable immediate uterine artery embolization for the conservative treatment of placenta accreta

International Nuclear Information System (INIS)

Bouvier, A.; Sentilhes, L.; Thouveny, F.; Bouet, P.-E.; Gillard, P.; Willoteaux, S.; Aubé, C.

2012-01-01

Aim: To evaluate the feasibility and efficacy of routine uterine artery embolization (UAE) immediately after planned caesareans performed in the cath lab for conservative treatment of placenta accreta. Materials and methods: A retrospective study included all patients who had a planned caesarean in the cath lab for conservative treatment of placenta accreta at Angers University Hospital, which is a tertiary care centre, from April 2001 to September 2010. Twelve patients underwent UAE immediately after caesarean with the placenta left partially or totally in situ. The success rate of embolization, blood loss, and complications were reported. Results: Diagnosis of abnormal placentation was confirmed by caesarean findings in 14 cases. Four patients had a percreta form with bladder invasion. In seven cases blood loss was insignificant and UAE was prophylactic; no secondary haemorrhage was observed in this group. Postpartum haemorrhage occurred in five cases: control of immediate postpartum bleeding by embolization was successful in three and failed in two leading to hysterectomy. In one case uterine necrosis occurred 6 weeks after embolization, requiring a hysterectomy. Delayed complications resulted in hysterectomy and partial bladder resection 3 months after delivery for one of the patients with placenta percreta. Conclusion: UAE immediately after a caesarean performed in the cath lab is a feasible therapeutic option for conservative treatment of placenta accreta. Advantages include reducing stress and risks associated with transferring women with potentially unstable haemodynamics.

Predicting local recurrence following breast-conserving treatment: parenchymal signal enhancement ratio (SER) around the tumor on preoperative MRI

International Nuclear Information System (INIS)

Kim, Mi Young; Cho, Nariya; Koo, Hye Ryoung; Yun, Bo La; Bae, Min Sun; Moon, Woo Kyung; Chie, Eui Kyu

2013-01-01

Background: The level of background parenchymal enhancement around tumor is known to be associated with breast cancer risk. However, there is no study investigating predictive power of parenchymal signal enhancement ratio (SER) around tumor for ipsilateral breast tumor recurrence (IBTR). Purpose: To investigate whether the breast parenchymal SER around the tumor on preoperative dynamic contrast-enhanced magnetic resonance imaging (MRI) is associated with subsequent IBTR in breast cancer patients who had undergone breast-conserving treatment. Material and Methods: Nineteen consecutive women (mean age, 44 years; range, 34-63 years) with breast cancer who developed IBTR following breast-conserving treatment and 114 control women matched for age, as well as T and N stages were included. We compared the clinicopathologic features of the two groups including nuclear grade, histologic grade, hormonal receptor status, human epidermal growth factor receptor-2 (HER-2) status, lymphovascular invasion, negative margin width, use of adjuvant therapy, and parenchymal SER around the tumor on preoperative DCE-MRI. The SER was measured on a slice showing the largest dimension of the tumor. Multivariate conditional logistic regression analysis was used to identify independent factors associated with IBTR. Results: In univariate analysis, ER negativity (odds ratio [OR] = 4.7; P = 0.040), PR negativity (OR = 4.0; P = 0.013), HER-2 positivity (OR = 3.6; P = 0.026), and a parenchymal SER greater than 0.53 (OR = 23.3; P = 0.011) were associated with IBTR. In multivariate analysis, ER negativity (OR = 3.8; P = 0.015) and a parenchymal SER greater than 0.53 (OR = 13.2; P = 0.040) on preoperative MRI were independent factors associated with IBTR. Conclusion: In addition to ER negativity, a higher parenchymal SER on preoperative MRI was an independent factor associated with subsequent IBTR in patients with breast cancer who had undergone breast-conserving treatment

Improving the Effectiveness of Interventions to Balance Conservation and Development: a Conceptual Framework

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Stephen T. Garnett

2007-06-01

Full Text Available There are numerous case studies around the world describing integrated conservation and development projects (ICDPs. Recently some localized syntheses have been published that use sophisticated statistics to identify patterns and causal linkages, but no attempt has yet been made to draw together lessons from across the globe. This paper is an attempt to provide a framework for such an analysis. A set of lessons is proposed for improving the prospects of ICDPs by giving consideration to each of the five capitals: natural, social, human, built, and financial. The language of ICDPs has been adopted by development agencies of all persuasions. There is now some urgency to identify the characteristics of the environment and the community in which success is most likely. This paper is intended as a step in that direction.

Brachytherapy in the conservative treatment of soft tissue sarcomas extending to neurovascular structures: an analysis of 38 cases

International Nuclear Information System (INIS)

Thomas, L.; Delannes, M.; Stoeckle, E.; Martel, P.; Pigneux, J.; Daly-Schveitzer, N.; Bui, B.N.; Chevreau, C.; Kantor, G.

1996-01-01

To evaluate the tolerance of neurovascular structures to brachytherapy, a retrospective review of our series was undertaken. Between May 1986 and January 1994, 85 patients with soft tissue sarcomas underwent conservative surgery and low-dose rate interstitial irradiation. Thirty-eight patients had tumors extending to neurovascular structures. Brachytherapy was part of initial treatment in 30 patients and was done in 7 cases for recurrent sarcomas. Afterloading catethers for brachytherapy were inserted intraoperatively and placed direct upon or under the neurovascular structures in the tumor bed. A mean dose of 20 Gy was delivered to the target volume. Thirty patients received 45 to 50 Gy of postoperative external irradiation. With a median follow-up of 39 months, the 3-year actuarial survival was 82.9%, the 3-year disease-free survival was 71.9% and the 3-year actuarial local control was 91%. The 3-year actuarial incidence of distant metastase was 28%. Acute side effects occurred in 12 patients requiring conservative surgical procedures in 6 cases. Significant late toxicity occurred in 8 patients : 2 lymphoedemas interfering with normal activity, 1 partial artery stenosis, 5 peripheral neuropathy (2 grade 2, 3 grade 3). Late toxicity has led to significant impairment of mobility in 4 patients. Limb preservation was achieved in every patient, no amputation was required. We conclude that integration of brachytherapy in the conservative treatment of soft tissue sarcomas extending to neurovascular structures can provide excellent local control with an acceptable level of toxicity

Neuropathological aspects of conservative treatment of scoliosis. A theoretical view point.

Science.gov (United States)

Czupryna, Krzysztof; Nowotny-Czupryna, Olga; Nowotny, Janusz

2012-01-01

An upright body posture cannot be maintained passively for reasons including a high location of the centre of gravity (COG) and a small support area. Proper alignment of body parts is maintained automatically, tending towards a pattern encoded in the CNS. A particularly important role in posture regulation is played by the short muscles of the back, which respond to being stretched with a contraction. During the early phase of scoliosis, the CNS automatically corrects abnormalities, but over time habituation occurs and the CNS treats them as something normal. Any attempt to restore proper body alignment is treated as an error and CNS automatically restores this abnormal pattern. With a prolonged deviation in body part alignment, CNS treats it as a defect and runs compensatory mechanisms to restore the balance of the body as a whole. Balance is ensured by postural compensation, but this does not restore proper body part alignment. In the treatment of scoliosis, it is important both to slow down progression and to prevent the development of abnormal postural habits, which are part of a vicious circle even without progression. Secondary prevention is therefore needed in all patients. Passive observation limits the possibilities for prevention and contradicts the principle of early implementation of rehabilitation. Depending on the size of the angle of curvature, recommended treatments of scoliosis comprise observation, corset bracing, and surgery. Physiotherapy is often treated as an unconventional and ineffective treatment. Often, the biggest problem is transferring the resulting correction to automatic maintenance of a correct posture in the vertical position. The aim of this paper was to discuss the conservative treatment of scoliosis with regard to difficulties maintaining the correct alignment of the body parts in the vertical position that accompany scoliosis.

Revitalizing Indigenous Languages, Cultures, and Histories in Montana, across the United States and around the Globe

Science.gov (United States)

Carjuzaa, Jioanna

2017-01-01

Many educators have sung the praises of Indian Education for All, Montana's constitutional mandate, and heard the successes of Montana's Indigenous language revitalization efforts which reverberate around the globe. Teaching Indigenous languages is especially, challenging since there are limited numbers of fluent speakers and scarce resources…

A combination of intramural stomach and portal venous air: conservative treatment

Directory of Open Access Journals (Sweden)

Prabin Sharma

2016-02-01

Full Text Available Emphysematous gastritis is a severe and rare form of gastritis with characteristic findings of intramural gas in the stomach. It is an acute life-threatening condition resulting from gas-producing microorganisms invading the stomach wall. Early diagnosis and initiation of treatment with bowel rest, hydration, and intravenous broad-spectrum antibiotics is imperative for an effective outcome. Surgical intervention is reserved for perforations, peritonitis, strictures, and uncontrolled disseminated sepsis. We present a case of an 82-year-old female with prior history of colon and uterine cancer on remission treated with surgeries who presented with bilious vomiting, abdominal discomfort, and nausea. She was tachycardic and had a diffusely tender abdomen with rebound on examination. Her laboratory results including blood count, serum chemistry, and coagulation studies were normal. She was diagnosed with emphysematous gastritis based on the characteristic radiographic findings of intramural stomach gas and also the presence of gas in the portal venous system. It is important to differentiate emphysematous gastritis from gastric emphysema because of the difference in management and prognosis, as emphysematous gastritis has a worse outcome and requires aggressive management. Despite an anticipated poor prognosis due to the known grave outcomes of emphysematous gastritis, our patient was successfully managed with conservative treatment. We concluded that she developed emphysematous gastritis probably secondary to immunosuppression and possible mucosal tears from multiple bouts of vomiting. She had a stable hospital course and resolution with medical management most likely due to early diagnosis and initiation of appropriate treatment.

Desmoid-type fibromatosis: a front-line conservative approach to select patients for surgical treatment.

Science.gov (United States)

Fiore, Marco; Rimareix, Françoise; Mariani, Luigi; Domont, Julien; Collini, Paola; Le Péchoux, Cecile; Casali, Paolo G; Le Cesne, Axel; Gronchi, Alessandro; Bonvalot, Sylvie

2009-09-01

Surgery is still the standard treatment for desmoid-type fibromatosis (DF). Recently, the Institut Gustave Roussy (IGR), Villejuif, France, reported a series of patients treated with a front-line conservative approach (no surgery and no radiotherapy). The disease remained stable in more than half of patients. This study was designed to evaluate this approach on the natural history of the disease in a larger series of patients. A total of 142 patients presenting to the IGR or Istituto Nazionale Tumori (INT), Milan, Italy, were initially treated using a front-line deliberately conservative policy. Their progression-free survival (PFS) was observed and a multivariate analysis was performed for major clinical variables. Seventy-four patients presented with primary tumor, 68 with recurrence. Eighty-three patients received a "wait & see" policy (W&S), whereas 59 were initially offered medical therapy (MT), mainly hormonal therapy and chemotherapy. A family history of sporadic colorectal cancer was present in 8% of patients. The 5-year PFS was 49.9% for the W&S group and 58.6% for the medically treated patients (P = 0.3196). Similar results emerged for primary and recurrent DF. Multivariate analysis identified no clinical variables as independent predictors of PFS. In the event of progression, all patients were subsequently managed safely. A conservative policy could be a safe approach to primary and recurrent DF, which could avoid unnecessary morbidity from surgery and/or radiation therapy. Half of patients had medium-term stable disease after W&S or MT. A multidisciplinary, stepwise approach should be prospectively tested in DF.

A DESCRIPTIVE STUDY OF CLOSED GLOBE INJURIES WITH HYPHAEMA

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Susan Philip

2017-05-01

Full Text Available BACKGROUND Eye injuries still remain one of the most common causes of unilateral blindness worldwide. In addition to the physical and psychological trauma to the patient, the direct and indirect costs to the society are enormous. Blunt eye injuries commonly result in traumatic hyphaema and are not an infrequent cause of presentation to the emergency units of many eye clinics. Aims of this study were- 1. To study the cause, clinical presentation, complications and visual outcome of closed globe injury with hyphaema. 2. To know the association between mode of injuries and associated lesions and visual outcome. MATERIALS AND METHODS Study Design and Statistical Analysis- A descriptive case series study was conducted at Regional Institute of Ophthalmology, Thiruvananthapuram for a period of one year, from October 2010 to September 2011, in all patients coming to the institute with hyphaema due to closed globe injury and willing to participate in the study. Patients with pre-existing ocular diseases were excluded. Data were analysed using computer software, Statistical Package for Social Sciences (SPSS version 10. Data are expressed in its frequency and percentage. To elucidate the associations and comparisons between different parameters, Chi square ( 2 test was used as a nonparametric test. For all statistical evaluations, a two-tailed probability of value, 6/60 either maintained that vision or improved. Only 10% of the study population had corneal blood staining. Majority of those who had initial hyphaema <1/3 rd , had normal initial intraocular pressure. Of the total 36 patients who had initial hyphaema less than 1/3 rd , 29 (80.6% had normal intraocular pressure on presentation. Of the 36 patients with initial hyphaema <1/3 rd , 28 (77.8% had normal intraocular pressure at 3 rd day. Those who had lenticular and posterior segment injury had poor visual outcome. In our study, initially only 15% had vision better than 6/12, but at the end of 180

THE REPRESENTATION OF EGYPTIAN PEOPLE’S VOICE IN THE JAKARTA GLOBE NEWS PHOTOGRAPHS

Directory of Open Access Journals (Sweden)

Fini Fitriani

2012-07-01

Full Text Available Abstract: As a product of mass media, news photograph is an image which provides the viewers with a valuable source of information and news story. All events captured in photographs turn into a news photo. Besides covering the news with fact, news photographs do not only have surface meanings, but also deeper meanings to be interpreted by each viewer. The phenomenon of demonstration, particularly the massive demonstration in Egypt in 2011, offers a good chance to discover how visual messages have been presented to guide interpretation of foreign news events. Principally, demonstration is an expression of the people’s voices, and thus, their voices are related closely with their demands, grievances and wishes related to the new government. Here, the photographs are able to portray and reflect the people’s voices through the compositions and contents (meanings involved in the photos. This study is aimed at discovering the portrayal of the voice of the people (the protesters in the news photographs of the Indonesian online newspaper, The Jakarta Globe. The data consist of 15 news photographs taken from The Jakarta Globe online newspaper published in January – October 2011. The study employs qualitative method framed with semiotic analysis using Roland Barthes’ theory of orders of signification and photographic message. The results of the study show that The Jakarta Globe visually constructs this event (demonstration by focusing on the human action (the protesters. Thus, the voice of the people is portrayed in the photo subjects (the protesters and the included objects of the photo. Meanwhile, the technical aspects of the photos play a meaningful role in emerging the portrayal of the people’s voice. There are four voices revealed by the people in the 15 photographs, namely the voice of freedom, the voice of peace, the voice of justice and the voice of human rights. The photo text including headlines and captions also interact with

A Portable Dynamic Laser Speckle System for Sensing Long-Term Changes Caused by Treatments in Painting Conservation.

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Pérez, Alberto J; González-Peña, Rolando J; Braga, Roberto; Perles, Ángel; Pérez-Marín, Eva; García-Diego, Fernando J

2018-01-11

Dynamic laser speckle (DLS) is used as a reliable sensor of activity for all types of materials. Traditional applications are based on high-rate captures (usually greater than 10 frames-per-second, fps). Even for drying processes in conservation treatments, where there is a high level of activity in the first moments after the application and slower activity after some minutes or hours, the process is based on the acquisition of images at a time rate that is the same in moments of high and low activity. In this work, we present an alternative approach to track the drying process of protective layers and other painting conservation processes that take a long time to reduce their levels of activity. We illuminate, using three different wavelength lasers, a temporary protector (cyclododecane) and a varnish, and monitor them using a low fps rate during long-term drying. The results are compared to the traditional method. This work also presents a monitoring method that uses portable equipment. The results present the feasibility of using the portable device and show the improved sensitivity of the dynamic laser speckle when sensing the long-term process for drying cyclododecane and varnish in conservation.

A Portable Dynamic Laser Speckle System for Sensing Long-Term Changes Caused by Treatments in Painting Conservation

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Pérez, Alberto J.; Braga, Roberto; Perles, Ángel; Pérez–Marín, Eva; García-Diego, Fernando J.

2018-01-01

Dynamic laser speckle (DLS) is used as a reliable sensor of activity for all types of materials. Traditional applications are based on high-rate captures (usually greater than 10 frames-per-second, fps). Even for drying processes in conservation treatments, where there is a high level of activity in the first moments after the application and slower activity after some minutes or hours, the process is based on the acquisition of images at a time rate that is the same in moments of high and low activity. In this work, we present an alternative approach to track the drying process of protective layers and other painting conservation processes that take a long time to reduce their levels of activity. We illuminate, using three different wavelength lasers, a temporary protector (cyclododecane) and a varnish, and monitor them using a low fps rate during long-term drying. The results are compared to the traditional method. This work also presents a monitoring method that uses portable equipment. The results present the feasibility of using the portable device and show the improved sensitivity of the dynamic laser speckle when sensing the long-term process for drying cyclododecane and varnish in conservation. PMID:29324692

Magnetic resonance imaging in the repair of ruptured Achilles tendons. Morphological difference in healing process between conservative and surgical treatment

International Nuclear Information System (INIS)

Nakano, Tetsuo; Tsuruta, Takao; Abe, Yasuyuki; Tani, Akifumi; Koga, Toshimitsu; Shimizu, Yasuhiro

1996-01-01

We observed the healing process of ruptured Achilles tendons in a series using magnetic resonance imaging. In six cases, tendons were repaired percutaneously with limited skin incisions. Seven cases were treated conservatively using unique functional braces. MR imaging revealed two different modes of conjoining. In the conservatively treated group, tendons inclined to conjoin in a dumbbell shape. In the surgically treated group, they inclined to conjoin in a spindle shape. The diameters of the ruptured part are wider in the spindle shape compared to the dumbbell shape at all stages. These findings suggest that surgical treatment is favorable for acquiring earlier strength. (author)

Enriching science, practice, and policy relevant to school psychology around the globe.

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Jimerson, Shane R

2016-03-01

This editorial provides a brief synthesis of the past, present, and future of School Psychology Quarterly, highlighting important contributions as an international resource to enrich, invigorate, enhance, and advance science, practice, and policy relevant to school psychology around the globe. Information herein highlights (a) the value of high quality and timely reviews, (b) publishing manuscripts that address a breadth of important topics relevant to school psychology, and (c) the structure and contributions of the special topic sections featured in School Psychology Quarterly. (c) 2016 APA, all rights reserved).

Lateral epicondylitis: Associations of MR imaging and clinical assessments with treatment options in patients receiving conservative and arthroscopic managements.

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Jeon, Ji Young; Lee, Min Hee; Jeon, In-Ho; Chung, Hye Won; Lee, Sang Hoon; Shin, Myung Jin

2018-03-01

We assessed the implications of MR imaging with clinical history in lateral epicondylitis management by evaluating imaging and clinical features in patients with lateral epicondylitis treated conservatively or operatively. Sixty patients with lateral epicondylitis treated conservatively (n = 38) or operatively (n = 22) from 2011-2015 were included. MR imaging findings of common extensor tendon (CET), lateral collateral ligament (LCL) complex, muscle oedema, ulnar nerve and elbow joint were reviewed. Clinical data recorded were frequency, duration and intensity of pain, history of trauma and injection therapy, range of motion. MRI-assessed CET and LCL complex abnormalities, muscle oedema, radiocapitellar joint widening, joint effusion/synovitis, pain frequency and intensity differed significantly between the two groups (p lateral epicondylitis. • MRI can reflect different disease severity between patients treated conservatively/operatively. • CET abnormality, muscle oedema were major MRI findings with operative treatment. • Patients in operative group were more likely to experience persistent pain. • MRI plus clinical symptoms could facilitate appropriate management for lateral epicondylitis.

Virtual Globes: Serving Science and Society

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Salman Qureshi

2012-08-01

Full Text Available Virtual Globes reached the mass market in 2005. They created multi-million dollar businesses in a very short time by providing novel ways to explore data geographically. We use the term “Virtual Globes” as the common denominator for technologies offering capabilities to annotate, edit and publish geographic information to a world-wide audience and to visualize information provided by the public and private sectors, as well as by citizens who volunteer new data. Unfortunately, but not surprising for a new trend or paradigm, overlapping terms such as “Virtual Globes”, “Digital Earth”, “Geospatial Web”, “Geoportal” or software specific terms are used heterogeneously. We analyze the terminologies and trends in scientific publications and ask whether these developments serve science and society. While usage can be answered quantitatively, the authors reason from the literature studied that these developments serve to educate the masses and may help to democratize geographic information by extending the producer base. We believe that we can contribute to a better distinction between software centered terms and the generic concept as such. The power of the visual, coupled with the potential of spatial analysis and modeling for public and private purposes raises new issues of reliability, standards, privacy and best practice. This is increasingly addressed in scientific literature but the required body of knowledge is still in its infancy.

Effect of conservative treatment on the renal outcome of children with primary hyperoxaluria type 1.

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Fargue, Sonia; Harambat, Jérôme; Gagnadoux, Marie-France; Tsimaratos, Michel; Janssen, Françoise; Llanas, Brigitte; Berthélémé, Jean-Pierre; Boudailliez, Bernard; Champion, Gérard; Guyot, Claude; Macher, Marie-Alice; Nivet, Hubert; Ranchin, Bruno; Salomon, Rémi; Taque, Sophie; Rolland, Marie-Odile; Cochat, Pierre

2009-10-01

Primary hyperoxaluria type 1 results from alanine:glyoxylate aminotransferase deficiency. Due to genotype/phenotype heterogeneity in this autosomal recessive disorder, the renal outcome is difficult to predict in these patients and the long-term impact of conservative management in children is unknown. We report here a multicenter retrospective study on the renal outcome in 27 affected children whose biological diagnosis was based on either decreased enzyme activity or identification of mutations in the patient or his siblings. The median age at first symptoms was 2.4 years while that at initiation of conservative treatment was 4.1 years; 6 children were diagnosed upon family screening. The median follow-up was 8.7 years. At diagnosis, 15 patients had an estimated glomerular filtration rate (eGFR) below 90, and 7 children already had stage 2-3 chronic kidney disease. The median baseline eGFR was 74, which rose to 114 with management in the 22 patients who did not require renal replacement therapy. Overall, 20 patients had a stable eGFR, however, 7 exhibited a decline in eGFR of over 20 during the study period. In a Cox regression model, the only variable significantly associated with deterioration of renal function was therapeutic delay with a relative risk of 1.7 per year. Our study strongly suggests that early and aggressive conservative management may preserve renal function of compliant children with this disorder, thereby avoiding dialysis and postponing transplantation.

Efficacy of two lion conservation programs in Maasailand, Kenya.

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Hazzah, Leela; Dolrenry, Stephanie; Naughton-Treves, Lisa; Naughton, Lisa; Edwards, Charles T T; Mwebi, Ogeto; Kearney, Fiachra; Frank, Laurence

2014-06-01

Lion (Panthera leo) populations are in decline throughout most of Africa. The problem is particularly acute in southern Kenya, where Maasai pastoralists have been spearing and poisoning lions at a rate that will ensure near term local extinction. We investigated 2 approaches for improving local tolerance of lions: compensation payments for livestock lost to predators and Lion Guardians, which draws on local cultural values and knowledge to mitigate livestock-carnivore conflict and monitor carnivores. To gauge the overall influence of conservation intervention, we combined both programs into a single conservation treatment variable. Using 8 years of lion killing data, we applied Manski's partial identification approach with bounded assumptions to investigate the effect of conservation treatment on lion killing in 4 contiguous areas. In 3 of the areas, conservation treatment was positively associated with a reduction in lion killing. We then applied a generalized linear model to assess the relative efficacy of the 2 interventions. The model estimated that compensation resulted in an 87-91% drop in the number of lions killed, whereas Lion Guardians (operating in combination with compensation and alone) resulted in a 99% drop in lion killing. © 2014 Society for Conservation Biology.

Long-term quality of life after conservative treatment versus surgery for different stages of acute sigmoid diverticulitis.

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Brandlhuber, Martina; Genzinger, Christian; Brandlhuber, Bernhard; Sommer, Wieland H; Müller, Mario H; Kreis, Martin E

2018-03-01

It is controversial whether patients fare better with conservative or surgical treatment in certain stages of acute diverticulitis (AD), in particular when phlegmonous inflammation or covered micro- or macro-perforation are present. The aim of this study was to determine long-term quality of life (QoL) for AD patients who received either surgery or conservative treatment in different stages. We included patients treated for AD at the University Hospital Grosshadern, Munich, Germany, between January 1, 2000, and December 31, 2010. Patients were classified by the Hansen and Stock (HS) classification, the modified Hinchey classification, and the German classification of diverticular disease (CDD). Pre-therapeutic staging was based on multidetector computed tomography. Long-term QoL was assessed by the Cleveland Global Quality of Life (CGQL) questionnaire, the Short Form 36 (SF-36), and the Gastrointestinal Quality of Life Index (GIQLI). Data are mean ± SEM. Patients with phlegmonous AD (HS type 2a, Hinchey Ia and CDD 1b, respectively) had a better long-term QoL on the GIQLI when they were operated (78.5 ± 2.5 vs. 70.7 ± 2.1; p life, patients fare better after elective sigmoid colectomy when abscess size exceeds 1 cm.

Examining the Structure of Vocational Interests in Turkey in the Context of the Personal Globe Model

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Vardarli, Bade; Özyürek, Ragip; Wilkins-Yel, Kerrie G.; Tracey, Terence J. G.

2017-01-01

The structural validity of the Personal Globe Inventory-Short (PGI-S: Tracey in J Vocat Behavi 76:1-15, 2010) was examined in a Turkish sample of high school and university students. The PGI-S measures eight basic interest scales, Holland's ("Making vocational choice," Prentice-Hall, Englewood Cliffs, 1997) six types, Prediger's ("J…

Conservative treatment of immature teeth with apical periodontitis using triple antibiotic paste disinfection

Directory of Open Access Journals (Sweden)

Hsin-Ju Wang

2016-06-01

Full Text Available The purpose of this report is to present conservative treatment for two immature premolars with apical periodontitis. A triple antibiotic paste was used to disinfect the root canal systems for revascularization. In both cases, residual vital pulp tissue was noted in the root canal system after the opening of each premolar. The canals in both cases were irrigated with copious sodium hypochlorite solution and medicated with a paste consisting of ciprofloxacin, metronidazole, and minocycline. The teeth were sealed with mineral trioxide aggregate and restored with composite resin. There were satisfactory outcomes after 18 months. The patients were asymptomatic, with radiographic evidence of complete resolution of radiolucency, continual thickening of dentinal walls, apical closure, and increased root length.

[Conservative treatment of nonspecific, chronic low back pain : Evidence of the efficacy - a systematic literature review].

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Bredow, J; Bloess, K; Oppermann, J; Boese, C K; Löhrer, L; Eysel, P

2016-07-01

Non-specific chronic low back pain (NSCLBP): Which conservative therapy shows an evident effectiveness - A review of the current literature. Our results are based on literature reviews of current randomised control studies, reviews and meta-analysis drawn from the Cochrane Library and Medline-Database between the years 2004 until 2015. German and English Studies were included. We focused on different conservative Treatments of NSCLBP, which are listed at, the NVL-Guidelines. Based on the given evidence we evaluated their effectiveness. As part of the review we identified 4657 Publications, 85 were included in this study. Therapeutic options such as bed rest, TENS, Massage, Spine Supports, Back Schools and Antidepressants showed no evident effectiveness. Injections, NSAR analgesic therapy, Thermotherapy and Opioid analgesic therapy indicated a short-time effectiveness. A long term success (> 6 weeks) however, can not be shown. Only the Movement therapy can, in the summation of the included studies, postulate an evident (Evidence Level I) long-term effect treating NSCLBP. Only a few therapy options indicate a significant evident effectiveness for treating NSCLBP conservatively. At short notice methods such as injection therapy, thermo-therapy and analgesic therapies with NSAR and/or opioids help coping the acute phase. In the long term only movement therapy seems to provide an evident effectiveness. In the case of therapy-refractory NSCLBP a multimodal therapy should be considered.

Prognostic factors for open globe injuries and correlation of Ocular Trauma Score at a tertiary referral eye care centre in Singapore

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Rupesh Agrawal

2013-01-01

Full Text Available Objective: To evaluate the factors influencing final vision outcome after surgical repair of open globe injuries and to correlate the Ocular trauma score. Materials and Methods: Retrospective case analysis of patients with open globe injuries at a tertiary referral eye care centre in Singapore was performed. Pre-operative factors affecting final vision outcome in patients with open globe injury and correlation of ocular trauma score in our study with international ocular trauma scoring system was performed. Results: Case records of 172 eyes with open globe injury were analyzed. Mean age was 36. 67 years. Mean follow up was 12.26 m. Males were pre-dominantly affected. Initial visual acuity was ≥20/40, 20/50 < 20/200, 20/200- CF, HM- PL and NLP in 24 (14%, 39 (22.7%, 16 (9.3%, 66 (38.4% and 27 (15.7% eyes respectively. Final visual acuity was ≤20/40, 20/50 < 20/200, 20/200- 1/200, HM- PL and NLP in 76 (44.2%, 28 (16.3%, 11 (6.4%, 30 (17.4% and 27 (15.7% eyes respectively. Ocular trauma score in our study correlates with international ocular trauma scoring system. Conclusion: The present study showed pre-operative variables such as mode of injury, pre-operative visual acuity, traumatic cataract, hyphaema, relative afferent papillary defect, vitreous lossand vitreous hemorrhage to be adversely affecting the final vision outcome. Our study showed a good synchrony with international ocular trauma score (OTS and based on this study we were able to validate application of OTS in Singapore population. Recognizing these factors can help the surgeon in evidence based counseling.

Percutaneous drainage in conservative therapy for perforated gastroduodenal ulcers.

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Oida, Takatsugu; Kano, Hisao; Mimatsu, Kenji; Kawasaki, Atsushi; Kuboi, Youichi; Fukino, Nobutada; Kida, Kazutoshi; Amano, Sadao

2012-01-01

The management of peptic ulcers has dramatically changed and the incidence of elective surgery for gastroduodenal peptic ulcers has markedly decreased; hence, the incidence of emergency surgery for perforated peptic ulcers has slightly increased. In select cases, conservative therapy can be used as an alternative for treating perforated gastroduodenal ulcers. In this study, we evaluated the efficacy of percutaneous abdominal drainage for the conservative treatment of perforated gastroduodenal ulcers. We retrospectively studied 51 patients who had undergone conservative therapy for perforated gastroduodenal ulcers. These patients were divided into 2 groups on the basis of the initial treatment with conservative therapy with or without percutaneous drainage: group PD included patients who had undergone percutaneous drainage and group NPD, patients who had undergone non-percutaneous drainage. In the PD group, 14.3% (n=3) of the patients did not respond to conservative therapy, while this value was 43.3% (n=13) in the NPD group. The 2 groups differed significantly with respect to conversion from conservative therapy to surgery (pperforated gastroduodenal ulcers should be performed only in the case of patients meeting the required criteria; its combination with percutaneous intraperitoneal drainage is effective as initial conservative therapy.

[Anterior Superior and Anterior Interior Iliac Spine Fractures. Comparison of the Results of Conservative and Surgical Treatment].

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Stančák, A; Kautzner, J; Havlas, V

2016-01-01

Avulsion fractures of the anterior superior iliac spine (ASIS) and anterior inferior iliac spine (AIIS) are rare injuries to the skeleton in children. They are most frequent in adolescent athletes, such as sprinters and long-distance runners, and football players. The authors present a group of patients treated at their department and compare the results of procedures used to manage different pelvic avulsion fractures. Between 2005 and 2012, 38 patients (31 boys and seven girls) with an average age of 15.1 years (range, 4-17 years) were treated. Fourteen patients with minimally displaced fractures were treated conservatively, 24 patients with fractures displaced more than 1 cm underwent surgery. All patients had a standard rehabilitation protocol. Post-operative assessments included: the range of motion in the hip; X-ray at 6 weeks, 3 months and 1 year; duration of bed rest; return to previous activities; occurrence of complications (heterotopic ossification, infection, etc). All patients returned to the pre-injury level of sports activities. Recovery was faster and early rehabilitation was better tolerated in patients treated surgically (p = 0.03), particularly in those with AIIS avulsion fractures. Ambulation with partial weight bearing was possible on average at 7.2 days (range, 2-10 days) in surgically treated patients and at 24.1 days (18-27 days) in conservatively treated patients; the difference was statistically significant (p = 0.02). The range of motion markedly improved in surgically treated patients as early as at 6 weeks while, in conservatively treated patients, the comparable outcome was achieved at 3 months of follow-up (p = 0.02). The time necessary for radiographic evidence of fragment union as well as full recovery was comparable in both patient groups. No deep wound infection was recorded; minor heterotopic ossification was detected in five patients, but no further treatment during follow-up was required. Indications for surgical treatment are

Congenital scoliosis - presentation of three severe cases treated conservatively.

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Weiss, H-R

2008-01-01

In view of the very limited data about conservative treatment of patients with congenital scoliosis (CS) available, early surgery is suggested already in mild cases with formation failures in the first three years of life. It is common sense that patients with failures of segmentation will not benefit from conservative treatment at all and the same applies to failures of formation with curves of >50 degrees in infancy. Two patients with rib synostosis denied surgery before entering the pubertal growth spurt. These patients have been treated conservatively with braces and Scoliosis In-Patient Rehabilitation (SIR) and now are beyond the pubertal growth spurt. One patient with a formation failure and a curve of >50 degrees lumbar has been treated with the help of braces and physiotherapy from 1.6 years on and is still under treatment now at the age of 15 years. Severe decompensation was prevented in the two patients with failure of segmentation, however a severe thoracic deformity is evident with underdeveloped lung function and severe restrictive ventilation disorder. The patient with failure of formation is well developed, now without cosmetic or physical complaints although his curve progressed at the end of the growth spurt due to final mal-compliance. Failures of segmentation should be advised to have surgery before entering the pubertal growth spurt. In case they deny, conservative treatment can at least in part be beneficial. For patients with failures of formation conservative treatment should be suggested in the first place because long-term outcomes of early surgery beyond pubertal growth spurt are not yet revealed.

Cosmesis with bilateral mammoreduction for conservative breast cancer treatment.

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Goffman, Thomas E; Schneider, Heather; Hay, Karen; Elkins, David E; Schnarrs, Robert A; Carman, Claire

2005-01-01

Over 7 years, 57 women with breast cancer underwent lumpectomy and bilateral mammoreduction. Physical complaints about large or lax breast shape were the predominate rationale. Two patients were immediately lost to follow-up, 55 patients remained and were followed every 3 months for an average of 1.6 years. This is the largest series traceable by computer and literature search. Chart review and patient examination in this retrospective review were utilized as the basis for data within the article. Collated notes from patients' doctors were assessed, as well as documented patient responses to the procedure. Pictures without head/face for identifiers were taken of the patients. Chart data were collected by clinicians, but were reviewed blindly by a statistician. The overall control and cosmesis rates as well as alleviation of heavy breast problems were noted. Only 6% of women had fair to poor cosmetic results; the majority (82%) had excellent to good results. Women with very large breasts or markedly relaxed breast tissue of concern to the patients proved optimal candidates for lumpectomy of cancer and bilateral mammoreduction in the conservative treatment of these cancers. There was a significant reduction in the physical complaints of the patients as well. For women with very pendulous or extremely large breasts, lumpectomy and bilateral mammoreduction may prove to be the optimal course of action.

Open-globe injuries: the experience at Hospital Sultanah Aminah, Johor Bahru.

Science.gov (United States)

Hooi, S H; Hooi, S T

2003-08-01

Between 1st January 1999 and 31st December 2000, 152 patients (156 eyes) with open-globe injuries were treated in the Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru. The majority were male (88.2%), Malay (63.2%), from the Johor Bahru district (51.3%) and aged between 21 and 30 years (23.7%). Most injuries were workplace-related (41.4%). Lens injury, retinal detachment, endophthalmitis, intraocular foreign bodies and phthisis occurred in 40.4%, 15.4%, 14.7%, 12.2% and 11.5% of eyes respectively. A favourable visual outcome occurred in 55.4% of eyes. Prognostic factors for visual outcome include presenting visual acuity, relative afferent pupillary defect, wound location, lens injury, retinal detachment and endophthalmitis.

Insights from life history theory for an explicit treatment of trade-offs in conservation biology.

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Charpentier, Anne

2015-06-01

As economic and social contexts become more embedded within biodiversity conservation, it becomes obvious that resources are a limiting factor in conservation. This recognition is leading conservation scientists and practitioners to increasingly frame conservation decisions as trade-offs between conflicting societal objectives. However, this framing is all too often done in an intuitive way, rather than by addressing trade-offs explicitly. In contrast, the concept of trade-off is a keystone in evolutionary biology, where it has been investigated extensively. I argue that insights from evolutionary theory can provide methodological and theoretical support to evaluating and quantifying trade-offs in biodiversity conservation. I reviewed the diverse ways in which trade-offs have emerged within the context of conservation and how advances from evolutionary theory can help avoid the main pitfalls of an implicit approach. When studying both evolutionary trade-offs (e.g., reproduction vs. survival) and conservation trade-offs (e.g., biodiversity conservation vs. agriculture), it is crucial to correctly identify the limiting resource, hold constant the amount of this resource when comparing different scenarios, and choose appropriate metrics to quantify the extent to which the objectives have been achieved. Insights from studies in evolutionary theory also reveal how an inadequate selection of conservation solutions may result from considering suboptimal rather than optional solutions when examining whether a trade-off exits between 2 objectives. Furthermore, the shape of a trade-off curve (i.e., whether the relationship between 2 objectives follows a concave, convex, or linear form) is known to affect crucially the definition of optimal solutions in evolutionary biology and very likely affects decisions in biodiversity conservation planning too. This interface between evolutionary biology and biodiversity conservation can therefore provide methodological guidance to

Conservative treatment of congenital false joint of shin in newborns and infants

Directory of Open Access Journals (Sweden)

O. V. Shchokin

2017-04-01

Full Text Available Congenital false joint of shin occurs in 1 case per 28 000 - 190 000 live births, but it is hard-to-treat and disabling disease. Objective: Improving treatment outcomes, reducing the number of surgical interventions for the treatment of congenital false joint of shin. Materials and Methods. The method is carried out using staged plaster casts with the gradual correction of deformities. When axis of the leg approximates to the normal one, axial load is added. First, it is done by tapping on the heel. When the child was 7-8 months old he was put on the legs and taught to walk. The plaster bandage is replaced by "Scotch cast" and "soft cast" bandage. The treatment lasted up to reaching of clinical effect – correction of shin deformation and absence of pathological mobility. Clinical effect must be confirmed by roentgenography which must demonstrate filling of false joint zone with bone tissue and restoration of intramedullary canal. During all the period of treating alternate courses of electrophoresis with calcium chloride, medical mud extracts and magnetic therapy are conducted. In the period from 1995 till 2015 in the Regional Zaporizhzhia Children Clinical Hospital 4 children (6 shins aged from 1 to 7 months with false joint of shin were treated using proposed method. Results and discussion. All 4 children (6 shins treated in clinic with proposed conservative method showed filling of false joint zone with bone tissue, restoration of intramedullary canal and significant extension of axis of the shin. The load on the leg in early terms results in compression of bone fragments (as in compression-distraction osteosynthesis, magnetic therapy, electrophoresis with calcium chloride and medical mud extracts promote active functioning of the muscles that improves regional blood supply and improves osteogenesis. Conclusions. Using the proposed method of treatment of congenital false joint of shins in newborns and infants can allow avoiding surgical

Globe Event | Lecture by Cédric Villani | 21 May

CERN Multimedia

Globe Info

2013-01-01

La naissance des idées - réflexions sur la nature et l’histoire de la mathématique et de la physique, by Cédric Villani.   Globe de la science et de l'innovation Route de Meyrin, 1211 Genève Tuesday 21 May 2013 at 6:00 p.m. The lecture will be in French - Interpreting available in English   Cédric Villani. In this lecture, Cédric Villani will explain what he considers to be the necessary “ingredients” for the birth of new ideas. Clearly a good brain is an essential factor, but that alone is not enough. The researcher must also have access to a wealth of literature, which is now greatly facilitated by the Internet. Motivation is another key component, although we do not really understand what incites it. Intellectual environment and constraints also drive creativity, as do perseverance and chance. An interesting idea has little chance of making a breakthrough w...

The recurrence risk of placenta accreta following uterine conserving management.

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Cunningham, K M; Anwar, A; Lindow, S W

2015-01-01

Placenta accreta is a condition of abnormal placental attachment that was usually treated by hysterectomy. Techniques to conserve the uterus are now commonly used and series of subsequent pregnancy outcomes have been reported. The recurrence risk of placenta accreta is now a relevant detail and is currently not known. This work was performed to calculate the recurrence risk by reviewing the published literature. A literature search using the terms "placenta accreta", "placenta percreta", "placenta increta", "abnormal placental attachment" and "placental attachment disorder" followed by hand-searching identified 6 papers that contained data concerning recurrence of placenta accreta in subsequent pregnancies following initial conservative treatment. Overall 407 pregnancies were recorded and 85.7% of women reported achieved a subsequent pregnancy following conservative treatment. The risk of recurrence of placental attachment disorder in a subsequent pregnancy was 19.9% (weighted mean, 95% CI 12.2-27.7). The recurrence risk of placental attachment disorder following uterine conservation treatments is 20% . This risk should be discussed with women with an antenatal diagnosis of a placental attachment disorder who may be considering uterine conservation in order to retain the option of a future pregnancy.

Effect of nitrogen fertilisation on the overall quality of minimally processed globe artichoke heads.

Science.gov (United States)

Lombardo, Sara; Restuccia, Cristina; Muratore, Giuseppe; Barbagallo, Riccardo N; Licciardello, Fabio; Pandino, Gaetano; Scifò, Giovanna O; Mazzaglia, Agata; Ragonese, Francesca; Mauromicale, Giovanni

2017-01-01

Although nitrogen (N) fertilisation is essential for promoting crop yield, it may also affect the produce quality. Here, the influence of three N fertiliser rates (0 kg ha -1 as a control, 200 kg ha -1 and 400 kg ha -1 referred to as N 0 , N 200 and N 400 , respectively) on the overall quality of minimally processed globe artichoke heads was investigated during refrigerated storage for 12 days. Throughout the storage time, N fertilised samples had higher inulin contents than those unfertilised. In addition, the respiratory quotient of N 200 and N 400 samples was 2-fold and 2.5-fold lower than N 0 ones, whose values were close to the normal range for vegetables. All the samples reported good microbiological standards, although N 200 and N 400 achieved lower mesophilic and psychotropic counts than N 0 throughout the storage time. After 8 and 12 days of refrigerated storage, the N 200 samples showed the highest scores of positive sensory descriptors. A fertiliser level of 200 kg N ha -1 is suitable for obtaining minimally processed globe artichoke heads with good nutritional, sensory and microbiological quality, characterised by low endogenous oxidase activities. Proper packaging systems and procedures are, however, crucial for extending the product shelf-life and, thus, promoting its exportation on a wider scale. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Predictive value of ocular trauma score in open globe combat eye injuries

International Nuclear Information System (INIS)

Islam, Q.

2016-01-01

Prediction of final visual outcome in ocular injuries is of paramount importance and various prognostic models have been proposed to predict final visual outcome. The objective of this study was to validate the predictive value of ocular trauma score (OTS) in patients with combat related open globe injuries and to evaluate the factors affecting the final visual outcome. Methods: Data of 93 patients admitted in AFIO Rawalpindi between Jan 2010 to June 2014 with combat related open globe ocular injuries was analysed. Initial and final best corrected visual acuity (BCVA) was categorized as No Light Perception (NLP), Light Perception (LP) to Hand Movement (HM), 1/200-19/200, 20/200-20/50, and =20/40. OTS was calculated for each eye by assigning numerical raw points to six variables and then scores were stratified into five OTS categories. Results: Mean age of study population was 28.77 ± 8.37 years. Presenting visual acuity was <20/200 (6/60) in 103 (96.23%) eyes. However, final BCVA of =20/40 (6/12) was achieved in 18 (16.82%) eyes, while 72 (67.28%) eyes had final BCVA of <20/200 (6/60). Final visual outcome in our study were similar to those in OTS study, except for NLP in category 1 (81% vs. 74%) and =20/40 in category 3 (30% vs. 41%). The OTS model predicted visual survival (LP or better) with a sensitivity of 94.80% and predicted no vision (NLP) with a specificity of 100%. Conclusion: OTS is a reliable tool for assessment of ocular injuries and predicting final visual outcome at the outset. (author)

Conservation of Charge and Conservation of Current

OpenAIRE

Eisenberg, Bob

2016-01-01

Conservation of current and conservation of charge are nearly the same thing: when enough is known about charge movement, conservation of current can be derived from conservation of charge, in ideal dielectrics, for example. Conservation of current is enforced implicitly in ideal dielectrics by theories that conserve charge. But charge movement in real materials like semiconductors or ionic solutions is never ideal. We present an apparently universal derivation of conservation of current and ...

Attitudes and treatment outcome of breast conservation therapy for stage I and II breast cancer using peroperative iridium-192 implant boost to the tumour bed

International Nuclear Information System (INIS)

Deo, S.V.S.; Shukla, N.K.; Mohanti, B.K.; Chawla, S.; Julka, P.K.; Rath, G.K.; Raina, V.

2001-01-01

Breast conservation therapy for early breast cancer is an established but grossly under-utilized treatment option in India for various reasons. Breast conservation therapy was offered to 200 suitable breast cancer patients between June 1993 and June 1998. Fifty-one patients (25%) opted for breast conservation and the remaining preferred mastectomy. In patients agreeing to conservation therapy, surgery was performed first along with peroperative implantation of iridium-192 to deliver a boost. Whole breast irradiation of 45 Gy was delivered 3-4 weeks after the boost. Cosmesis was assessed at the end of 6 months from completion of therapy. The main reason for refusal of breast conservation therapy was fear of recurrence in the remaining breast (60%). There were no loco-regional failures in our study at a median follow up of 42 months; one patient experienced a systemic relapse. Cosmesis was good to excellent in 80% of patients. Breast conservation therapy using peroperative iridium-192 implant provides excellent loco-regional disease control and cosmesis. The results of our study indicate that patient preference for mastectomy is an important reason for the under-utilization of breast conservation therapy in India. Copyright (2001) Blackwell Science Pty Ltd

Percutaneous Vertebroplasty Compared to Conservative Treatment in Patients With Painful Acute or Subacute Osteoporotic Vertebral Fractures: Three-Months Follow-up in a Clinical Randomized Study

DEFF Research Database (Denmark)

Rousing, Rikke; Andersen, Mikkel Østerheden; Jespersen, Stig M.

2009-01-01

STUDY DESIGN: Clinical randomized study. OBJECTIVE: The aim of this study is to compare percutaneous vertebroplasty (PVP) to conservative treatment of patients with osteoporotic vertebral fractures in a clinical randomized study with respect to pain, physical and mental outcome, and to asses...... patients (41 females) were included from January 2001 until January 2008. Patients with acute (treatment. Pain was assessed with a visual analogue scale and physical and mental...... within both groups and between the groups after 3 months with a few exceptions. We observed 2 adjacent fractures in the PVP group and non in the conservative group. CONCLUSION: The majority of patients with acute or subacute painful osteoporotic compression fractures in the spine will recover after a few...

Point-of-service, quantitative analysis of ascorbic acid in aqueous humor for evaluating anterior globe integrity

Science.gov (United States)

Gartia, Manas R.; Misra, Santosh K.; Ye, Mao; Schwartz-Duval, Aaron; Plucinski, Lisa; Zhou, Xiangfei; Kellner, David; Labriola, Leanne T.; Pan, Dipanjan

2015-11-01

Limited training, high cost, and low equipment mobility leads to inaccuracies in decision making and is concerning with serious ocular injuries such as suspected ruptured globe or post-operative infections. Here, we present a novel point-of-service (POS) quantitative ascorbic acid (AA) assay with use of the OcuCheck Biosensor. The present work describes the development and clinical testing of the paper-based biosensor that measures the changes in electrical resistance of the enzyme-plated interdigitated electrodes to quantify the level of AA present in ocular fluid. We have demonstrated the proof-of-concept of the biosensor testing 16 clinical samples collected from aqueous humor of patients undergoing therapeutic anterior chamber paracentesis. Comparing with gold standard colorimetric assay for AA concentration, OcuCheck showed accuracy of >80%, sensitivity of >88% and specificity of >71%. At present, there are no FDA-approved POS tests that can directly measures AA concentration levels in ocular fluid. We envisage that the device can be realized as a handheld, battery powered instrument that will have high impact on glaucoma care and point-of-care diagnostics of penetrating ocular globe injuries.

Total Maxillary Reconstruction With a Bi-Paddle Double-Barrel Osteocutaneous Fibular Flap and Arteriovenous Saphenous Loop After a Globe-Sparing Total Maxillectomy Due to Osteosarcoma.

Science.gov (United States)

Tseng, Wan-Ling; Chang, Tzu-Yen; Hung, Kuo-Shu; Chen, Szu-Han; Hsiao, Jenn-Ren; Lee, Yao-Chou

2017-01-01

The titanium mesh or bone graft is usually used for orbital support after a globe-sparing total maxillectomy. However, its use can invite complications, such as infection, exposure, and absorption, especially for patients who require adjuvant radiotherapy. Here, the authors present a patient who received total maxillary reconstruction with an osteocutaneous fibular flap. A 53-year-old man with the diagnosis of maxillary osteosarcoma received a globe-sparing total maxillectomy. A bi-paddle double-barrel osteocutaneous fibular flap was used for orbital support, alveolar ridge recreation, and oro-sino-nasal separation. The short pedicle length inherent in the double-barrel design of the fibular flap was overcome by creating an arteriovenous saphenous loop. The postoperative recovery was uneventful. During the 9 months follow-up, the patient was tumor-free and satisfied with his appearance, speech, and intake functions. Reconstruction with a bi-paddle double-barrel osteocutaneous fibular flap after a globe-sparing total maxillectomy can achieve satisfactory aesthetic and functional results.

Quality control in breast conservation