Sample records for gibbon hylobates lar
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Barelli, Claudia; Huffman, Michael A
2017-03-01
Leaf swallowing behavior, known as a form of self-medication for the control of nematode and tapeworm infection, occurs widely in all the African great apes (Pan troglodytes schweinfurthii, P. t. troglodytes, P. t. verus, P. t. vellerosus, Pan paniscus, Gorilla gorilla graueri), except mountain gorillas. It is also reported to occur in a similar context across a wide array of other animal taxa including, domestic dogs, wolves, brown bears, and civets. Despite long-term research on Asian great and small apes, this is the first report of leaf swallowing in an Asian species, the white-handed gibbon (Hylobates lar) in Khao Yai National Park, central Thailand. We present the first evidence of leaf swallowing (Gironniera nervosa Planch CANNABACEA) behavior (N = 5 cases) and parasite (Streptopharagus pigmentatus) expulsion (N = 4 cases), recorded during 4,300 hr of direct animal observations during two distinct research projects. We recovered 4-18 rough, hairy, and hispid surfaced leaves from each sample, undigested and folded, from the freshly evacuated feces of five different individuals (2 males, 3 females, 5 to 34+ years old) living in three different social groups, between the hours of 06:00 to 10:30. Based on close inspection of the leaves, as observed in chimpanzees, it was clear that they were taken into the mouth, one at a time, folded and detached from the stem with the teeth before swallowing them whole. All instances occurred during the rainy season, the time when nematode worms were also found in the feces, although they were not found together with leaves in the same feces. These striking similarities in the details of leaf swallowing between white-handed gibbons and African great apes, and other animal species, suggest a similar self-medicative function. © 2016 Wiley Periodicals, Inc.
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Object permanence tests on gibbons (Hylobatidae).
Fedor, Anna; Skollár, Gabriella; Szerencsy, Nóra; Ujhelyi, Mária
2008-11-01
Ten gibbons of various species (Symphalangus syndactylus, Hylobates lar, Nomascus gabriellae, and Nomascus leucogenys) were tested on object permanence tasks. Three identical wooden boxes, presented in a linear line, were used to hide pieces of food. The authors conducted single visible, single invisible, double invisible, and control displacements, in both random and nonrandom order. During invisible displacements, the experimenter hid the object in her hand before putting it into a box. The performance of gibbons was better than expected by chance in all the tests, except for the randomly ordered double displacement. However, individual analysis of performance showed great variability across subjects, and only 1 gibbon is assumed to have solved single visible and single invisible displacements without recourse to a strategy that the control test eliminated. (PsycINFO Database Record (c) 2008 APA, all rights reserved).
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Directory of Open Access Journals (Sweden)
Alongkoad Tanomtong
2008-07-01
Full Text Available Cytogenetics of the pileated gibbon (Hylobates pileatus at Nakhon Ratchasima Zoo, Thailand, was studied. Bloodsamples were taken from two female and two male gibbons. After lymphocyte culture, the mitotic chromosome preparationwas done by hypotonic-fixation-air-drying method and conventional Giemsas staining. The results show that diploid chromosomenumber was 44 (2n=2x=44, and the fundamental number (NF were 88 chromosomes in both female and male.The autosomes consist of 12 large metacentric, 6 medium metacentric, 2 medium submetacentric, 2 medium acrocentric, 12small metacentric and 8 small submetacentric chromosomes. In addition, the chromosome 15 showed clearly observablesatellite chromosomes. The X chromosome was a medium submetacentric chromosome and the Y chromosome was a tinyacrocentric chromosome. The karyotype formula for the pileated gibbon is as follows:2n (44 = Lm12+Mm6+Msm2+Ma2+Sm12+Ssm8+sex-chromosomes
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DEFF Research Database (Denmark)
Heller, R; Pedersen, Adam Frederik Sander; Wang, Christian William
2010-01-01
Vocal characteristics have been used extensively to distinguish different taxonomic units of gibbons (family Hylobatidae). The agile gibbon (Hylobates agilis) has a disjunct distribution range in the Southeast Asian archipelago (remnants of the former Sunda landmass), and populations on different...... islands are currently recognized as distinct subspecies or even species. We recorded great calls from female agile gibbons from two populations on Sumatra and two populations on Borneo and examined the vocal variability on four levels: within-individuals, between-individuals, between...
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Gibbon travel paths are goal oriented.
Asensio, Norberto; Brockelman, Warren Y; Malaivijitnond, Suchinda; Reichard, Ulrich H
2011-05-01
Remembering locations of food resources is critical for animal survival. Gibbons are territorial primates which regularly travel through small and stable home ranges in search of preferred, limited and patchily distributed resources (primarily ripe fruit). They are predicted to profit from an ability to memorize the spatial characteristics of their home range and may increase their foraging efficiency by using a 'cognitive map' either with Euclidean or with topological properties. We collected ranging and feeding data from 11 gibbon groups (Hylobates lar) to test their navigation skills and to better understand gibbons' 'spatial intelligence'. We calculated the locations at which significant travel direction changes occurred using the change-point direction test and found that these locations primarily coincided with preferred fruit sources. Within the limits of biologically realistic visibility distances observed, gibbon travel paths were more efficient in detecting known preferred food sources than a heuristic travel model based on straight travel paths in random directions. Because consecutive travel change-points were far from the gibbons' sight, planned movement between preferred food sources was the most parsimonious explanation for the observed travel patterns. Gibbon travel appears to connect preferred food sources as expected under the assumption of a good mental representation of the most relevant sources in a large-scale space.
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Dooley, Helen M; Judge, Debra S; Schmitt, Lincoln H
2013-01-01
Kloss gibbons (Hylobates klossii) are endemic to the Mentawai Islands in Indonesia and are one of only two gibbon species in which mated pairs do not sing duets. This is the first long-term study of the factors influencing the singing activity of Kloss gibbons within a northern Siberut Island population and follows two previous studies in central Siberut nearly 30 years ago. We collected data on the presence/absence of male and female singing within the study area on 198 days and within a focal group on 47 days. Rainfall during the time period in which they normally sing inhibits singing in both males and females. Our study supports the hypothesis that male and female songs function in intrasexual resource defence, as singing is associated with singing by same-sex neighbours, and same-sex choruses are more likely to occur after one or more days of silence (from that sex), suggesting there is pressure for individuals to communicate with same-sex neighbours regularly. Singing was not coordinated within a mated pair, suggesting that vocal coordination of the pair has been lost with the loss of the duet and that Kloss gibbon songs do not convey information to neighbours about the strength of the pair bond. On days when males sang predawn, females were more likely to sing after dawn and earlier in the morning. Additionally, the number of groups singing in female choruses was positively associated with the number of males that had sung in the predawn male chorus. We suggest that female songs have an intersexual territory defence as well as an intrasexual function.
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Wallace, Emma K; Kingston-Jones, Mark; Ford, Matthew; Semple, Stuart
2013-01-01
The use of music as enrichment has rarely been explored in zoos, despite evidence that music has a positive effect on a range of laboratory housed animals. In this study of moloch gibbons, Hylobates moloch, at Howletts Wild Animal Park (Kent, England), instrumental classical music was played to eight individuals in two family groups. Music was played 7 hr a day during three of six study weeks for each group, alternating with control weeks in which no music was played. In focal watches, data were recorded on a measure of activity, brachiation, and on two rates of affiliative behavior, giving and receiving grooming. In addition, to assess potential impacts on emotional state, data were recorded on self-scratching and self-grooming, two widely used indices of anxiety or stress. Analyses were carried out for each individual separately, as previous studies of primates indicate animals may differ in their response to enrichment. Results revealed little evidence for effects of music on gibbons' behavior. During the music compared to control weeks, the adult male from one group showed higher rates of self-scratching and higher durations of both self-grooming and grooming others. The adult female from the same group was groomed more during the music weeks than control weeks. For the six other animals, no significant differences in behaviors were seen between music and control conditions. Our findings suggest music may not be an effective enrichment for captive gibbons, and further highlight the importance of considering individual differences when assessing the effects of potential enrichment. Copyright © 2013 Wiley Periodicals Inc.
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In-Situ and Ex-Situ status of the Javan Gibbon and the role of zoos in conservation of the species
Nijman, V.
2006-01-01
The Javan gibbon Hylobates moloch is confined to the last remnants of rainforest on the island of Java, Indonesia. As of 2002, the species has been recorded in 29 forest areas, and the wild population is conservatively estimated at 4100-4500 individuals. Over 95% of the gibbons are in populations of
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Directory of Open Access Journals (Sweden)
S.M. Cheyne
2013-03-01
Full Text Available Data are presented on the locomotion of Bornean Agile Gibbons (Hylobatesalbibarbis in a disturbed peat-swamp forest. Our results indicate that gibbons favour continuous-canopy forest, higher canopy heights and trees with a larger diameter at breast height. Gibbons select these trees despite the study site being dominated by broken-canopy forest and small trees. Gibbons also change frequently between brachiation, climbing, clambering and bipedal walking in this disturbed forest depending on the size of gap to be crossed. Gibbons are shown to be capable of adapting to some human-induced disturbances in forest continuity and canopy height, and to the presence of smaller trees, e.g., after selective logging. Despite this, gibbons are still limited to crossing gaps of =12m in a single movement, and more research is needed to quantify levels of disturbance gibbons can tolerate.
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Shi, Cheng-Min; Yang, Ziheng
2018-01-01
Abstract The phylogenetic relationships among extant gibbon species remain unresolved despite numerous efforts using morphological, behavorial, and genetic data and the sequencing of whole genomes. A major challenge in reconstructing the gibbon phylogeny is the radiative speciation process, which resulted in extremely short internal branches in the species phylogeny and extensive incomplete lineage sorting with extensive gene-tree heterogeneity across the genome. Here, we analyze two genomic-scale data sets, with ∼10,000 putative noncoding and exonic loci, respectively, to estimate the species tree for the major groups of gibbons. We used the Bayesian full-likelihood method bpp under the multispecies coalescent model, which naturally accommodates incomplete lineage sorting and uncertainties in the gene trees. For comparison, we included three heuristic coalescent-based methods (mp-est, SVDQuartets, and astral) as well as concatenation. From both data sets, we infer the phylogeny for the four extant gibbon genera to be (Hylobates, (Nomascus, (Hoolock, Symphalangus))). We used simulation guided by the real data to evaluate the accuracy of the methods used. Astral, while not as efficient as bpp, performed well in estimation of the species tree even in presence of excessive incomplete lineage sorting. Concatenation, mp-est and SVDQuartets were unreliable when the species tree contains very short internal branches. Likelihood ratio test of gene flow suggests a small amount of migration from Hylobates moloch to H. pileatus, while cross-genera migration is absent or rare. Our results highlight the utility of coalescent-based methods in addressing challenging species tree problems characterized by short internal branches and rampant gene tree-species tree discordance. PMID:29087487
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Osthoff, G; Hugo, A; de Wit, M; Nguyen, T P M; Seier, J
2009-04-01
The nutrient content and fatty acid composition of vervet monkey milk has been determined and is compared with rhesus macaque, and two hominoid apes, the white handed gibbon and gorilla. With 15.7+/-4.1 g protein, 33.1+/-9.4 g fat, and 85.1+/-7.5 g lactose per kg milk, vervet monkey milk does not differ from that of rhesus macaque, and is within the range of other primates. Small amounts (>1 g kg(-1)) of oligosaccharides, glucose, galactose and fucose were noted. In comparison, gorilla milk has a low fat content of 13.8 g kg(-1), but contains high levels of oligosaccharides at 7.0 g kg(-1) milk. The hominoid partner, the white handed gibbon, contains no oligosaccharides and a milk fat content similar to other hominoid species. Differences between vervet monkey and rhesus macaque milks were observed in the electrophoretic pattern of the milk proteins, mainly amongst the kappa- and gamma-caseins, which also differ from that of the hominids. The fatty acid contents of these milks differ from studies where a natural diet of leafy material was available in that a low content of alpha-linolenic acid (18:3n-3) was noted. A phylogenetic effect is observed for the content of 8:0, 10:0 fatty acids between the Cercopithecidae and Hominoidea, and a further phylogenetic effect suggested between the Hylobatidae and Hominidae.
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Life history theory and dental development in four species of catarrhine primates.
Dirks, Wendy; Bowman, Jacqui E
2007-09-01
Dental development was reconstructed in several individuals representing four species of catarrhine primates--Symphalangus syndactylus, Hylobates lar, Semnopithecus entellus priam, and Papio hamadryas--using the techniques of dental histology. Bar charts assumed to represent species-typical dental development were constructed from these data and estimated ages at first and third molar emergence were plotted on them along with ages at weaning, menarche, and first reproduction from the literature. The estimated age at first molar emergence appears to occur at weaning in the siamang, lar gibbon, and langur, and just after weaning in the baboon. Age at menarche and first reproduction occur earlier relative to dental development in both cercopithecoids than in the hylobatids, suggesting that early reproduction may be a derived trait in cercopithecoids. The results are examined in the context of life history theory.
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Directory of Open Access Journals (Sweden)
Dena J Clink
Full Text Available Effectively characterizing primate diets is fundamental to understanding primate behavior, ecology and morphology. Examining temporal variation in a species' diet, as well as comparing the responses of different species to variation in resource availability, can enhance understanding of the evolution of morphology and socioecology. In this study, we use feeding data collected over five years to describe the diets of two sympatric Southeast Asian primate species of similar body size: white-bearded gibbons (Hylobates albibarbis and red leaf monkeys (Presbytis rubicunda rubida, in Gunung Palung National Park, West Kalimantan, Indonesia. Long-term data sets are especially important for characterizing primate diets in Southeast Asia, where the forests exhibit supra-annual mast fruiting events. We found that gibbons were mainly frugivorous, with fruit and figs comprising 70% of their 145 independent feeding observations, whereas leaf monkeys ate a substantial amount of seeds (26%, fruits and figs (26.5% and leaves (30%, n = 219 independent feeding observations. Leaf monkeys consumed a higher number of plant genera, and this was due mostly to the non-frugivorous portion of their diet. To investigate resource selection by these primates we utilized two different approaches: the Manly Selectivity Ratio, which did not take into account temporal variation of resource availability, and a model selection framework which did incorporate temporal variation. Both species selected figs (Ficus more than predicted based on their availability under the Manly Selectivity Ratio. Model selection allowed us to determine how these primates alter the proportion of leaves, flowers, seeds, figs and fruit in their diets in response to variation in fruit availability. When fruits were scarce, both gibbons and leaf monkeys incorporated more leaves and figs into their diets, indicating that these two food classes are fallback foods for these primates. We discuss how different
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Effect of diet on dental development in four species of catarrhine primates.
Dirks, Wendy
2003-09-01
In this study, dental development is described in two pairs of closely related catarrhine primate species that differ in their degree of folivory: 1) Hylobates lar and Symphalangus syndactylus, and 2) Papio hamadryas hamadryas and Semnopithecus entellus. Growth increments in histological thin sections are used to reconstruct the chronology of dental development to determine how dental development is accelerated in the more folivorous species of each pair. Although anterior tooth formation appears to be unrelated to diet, both S. syndactylus and S. entellus initiate the slowest-forming molar earlier than the related less-folivorous species, which supports the hypothesis that dental acceleration is related to food processing. S. syndactylus initiates M2 crown formation at an earlier age than H. lar, and S. entellus initiates and completes M3 at an earlier age than P. h. hamadryas. Similar stages of M3 eruption occur earlier in the more folivorous species; however, the sex of the individual may also play a role in creating such differences. Although the age at M3 emergence is close to that reported for the end of body mass growth in lar gibbons, hamadryas baboons, and Hanuman langurs, M3 emergence may not be coupled to body mass growth in siamangs. Copyright 2003 Wiley-Liss, Inc.
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Serological evidence of herpesvirus infection in gibbons
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Ratanakorn Parntep
2002-05-01
Full Text Available Abstract Background Herpesviruses are not only infectious agents of worldwide distribution in humans, but have also been demonstrated in various non-human primates as well. Seventy-eight gibbons were subjected to serological tests by ELISA for herpes simplex virus type 1 (HSV-1, herpes simplex virus type 2 (HSV-2, Epstein-Barr virus (EBV and cytomegalovirus (CMV. Results The prevalence of IgG antibodies against HSV-1, HSV-2, EBV and CMV was 28.2%, 28.2%, 14.1% and 17.9%, respectively. Conclusions Antigenic cross-reactivity is expected to exist between the human herpesviruses and gibbon herpesviruses. Gibbons have antibodies to human herpesviruses that may reflect zoonotic infection with human herpesviruses or infection with indigenous gibbon herpesviruses. Therefore, it is difficult to draw concrete conclusions from serological studies alone. Identification should be based on further isolation and molecular characterization of viruses from seropositive animals.
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Ecology and social system of northern gibbons living in cold seasonal forests.
Guan, Zhen-Hua; Ma, Chang-Yong; Fei, Han-Lan; Huang, Bei; Ning, Wen-He; Ni, Qing-Yong; Jiang, Xue-Long; Fan, Peng-Fei
2018-07-18
Gibbons in China represent the northernmost margin of present day gibbon species distribution (around N25°). Compared to tropical habitats, northern gibbon habitats are characterized by low temperatures and remarkable seasonal variation in fruit abundance. How gibbons adapt to their cold and seasonal habitats and what ecological factors affect their sociality are key questions for understanding their ecology and social system evolution, the elucidation of which will contribute to the conservation of these special populations/species. According to preliminary short-term studies, northern gibbons consume more leaves and use larger home ranges than tropical gibbons. Interestingly, some Nomascus groups consist of more than one adult female. However, these preliminary results are not well understood or incorporated into current socio-ecological theories regarding gibbon species. To better understand northern gibbons, our team has systematically studied three habituated groups of Nomascus concolor, three groups of N. nasutus, and two habituated groups of Hoolock tianxing since 2002. In this paper, we stress the challenges facing gibbons living in northern habitats and summarize their behavioral adaptations to their harsh environments. We also describe the northern gibbon social system and discuss the potential relationships between their ecology and sociality. Finally, we highlight future research questions related to northern gibbons in China.
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Ecology and social system of northern gibbons living in cold seasonal forests
Directory of Open Access Journals (Sweden)
Zhen-Hua Guan
2018-07-01
Full Text Available Gibbons in China represent the northernmost margin of present day gibbon species distribution (around N25°. Compared to tropical habitats, northern gibbon habitats are characterized by low temperatures and remarkable seasonal variation in fruit abundance. How gibbons adapt to their cold and seasonal habitats and what ecological factors affect their sociality are key questions for understanding their ecology and social system evolution, the elucidation of which will contribute to the conservation of these special populations/species. According to preliminary short-term studies, northern gibbons consume more leaves and use larger home ranges than tropical gibbons. Interestingly, some Nomascus groups consist of more than one adult female. However, these preliminary results are not well understood or incorporated into current socio-ecological theories regarding gibbon species. To better understand northern gibbons, our team has systematically studied three habituated groups of Nomascus concolor, three groups of N. nasutus, and two habituated groups of Hoolock tianxing since 2002. In this paper, we stress the challenges facing gibbons living in northern habitats and summarize their behavioral adaptations to their harsh environments. We also describe the northern gibbon social system and discuss the potential relationships between their ecology and sociality. Finally, we highlight future research questions related to northern gibbons in China.
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Church, Russell M.
2002-04-28
This article provides an overview of the published research of John Gibbon. It describes his experimental research on scalar timing and his development of scalar timing theory. It also describes his methods of research which included mathematical analysis, conditioning methods, psychophysical methods and secondary data analysis. Finally, it describes his application of scalar timing theory to avoidance and punishment, autoshaping, temporal perception and timed behavior, foraging, circadian rhythms, human timing, and the effect of drugs on timed perception and timed performance of Parkinson's patients. The research of Gibbon has shown the essential role of timing in perception, classical conditioning, instrumental learning, behavior in natural environments and in neuropsychology.
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Gibbon Aggression During Introductions: An International Survey.
Harl, Heather; Stevens, Lisa; Margulis, Susan W; Petersen, Jay
2016-01-01
Little is known regarding the prevalence of aggression seen during introductions of captive gibbons (Hylobatidae). In this study, an online survey was developed to quantify and collect contextual details regarding the frequency and types of aggression seen during introductions of captive gibbons (Hylobatidae). Nineteen percent of institutions (17 institutions) reported observing aggression, and 6 of these institutions recorded multiple instances of aggression, though a vast majority of these cases resulted in mild injuries or none at all. The female was the primary aggressor in 23% of cases, the male was the primary aggressor in 58% of cases, and both were the primary aggressor in 1 case. Although these aggressive interactions were often not associated with a known cause, 27% of cases were associated with food displacement. In most cases, management changes, including trying new pairings, greatly reduced situational aggression, suggesting that individual personalities may play a factor in aggression. These data begin to explain the extent of aggression observed in captive gibbons; future studies will address possible correlations with aggression and introduction techniques.
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Four-center bubbled BPS solutions with a Gibbons-Hawking base
Heidmann, Pierre
2017-10-01
We construct four-center bubbled BPS solutions with a Gibbons-Hawking base space. We give a systematic procedure to build scaling solutions: starting from three-supertube configurations and using generalized spectral flows and gauge transformations to extend to solutions with four Gibbons-Hawking centers. This allows us to construct very large families of smooth horizonless solutions that have the same charges and angular momentum as supersymmetric black holes with a macroscopically large horizon area. Our construction reveals that all scaling solutions with four Gibbons Hawking centers have an angular momentum at around 99% of the cosmic censorship bound. We give both an analytical and a numerical explanation for this unexpected feature.
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Hai, Bach Thanh; Chen, Jin; McConkey, Kim R.; Dayananda, Salindra K.
2018-04-01
Understanding the mutualisms between frugivores and plants is essential for developing successful forest management and conservation strategies, especially in tropical rainforests where the majority of plants are dispersed by animals. Gibbons are among the most effective seed dispersers in South East Asia's tropical forests, but are also one of the highly threatened arboreal mammals in the region. Here we studied the seed dispersal of the Pacific walnut (Dracontomelon dao), a canopy tree which produces fruit that are common in the diet of the endangered southern yellow-cheeked crested gibbon (Nomascus gabriellae). We found that gibbons were the most effective disperser for this species; they consumed approximately 45% of the fruit crop, which was four times more than that consumed by macaques - the only other legitimate disperser. Gibbons tracked the temporal (but not spatial) abundance of ripe fruits, indicating this fruit was a preferred species for the gibbon. Both gibbons and macaques dispersed the majority (>90%) of the seeds at least 20 m away from parent crowns, with mean dispersal distances by gibbons measuring 179.3 ± 98.0 m (range: 4-425 m). Seeds defecated by gibbons germinated quicker and at greater rates than seeds spat by macaques, or in undispersed fruits. Gibbon-dispersed seeds were also more likely to be removed by unknown seed predators or unknown secondary dispersers. Overall, gibbons play a key role in the regeneration of the Pacific walnut. Our findings have significant implications both for the management of the Pacific walnut tree dominating tropical rainforest as well as the reintroduction program of the Southern yellow-cheeked crested gibbon.
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Sex determination in gibbons of genus Nomascus using non-invasive method
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Petra Bolechová
2016-01-01
Full Text Available Gibbons of the genus Nomascus have a strong sexual dimorphism and dichromatism. As they mature, both sexes develop sex-specific pelage colour. In combination with physical similarities in the genitalia with both sexes, there are problems with determining the sex of young individuals compared to other genus of gibbons. This is a pilot study applying a multiplex polymerase chain reactions based on a non-invasive method for sex determination of gibbons. The study was conducted on 22 faecal samples from gibbons of the genus Nomascus. The animals were monitored by staff so that the samples were identified correctly and each sample was collected immediately after the defecation. Results confirmed the sex in all adult and juvenile animals with known sex; and 2 females and 5 males in juveniles were determined with unknown sex. The results of direct examination completely corresponded with the PCR results. The PCR reaction with template DNA isolated from faecal material required BSA usage, however, we observed the occurrence of nonspecific fragments. This did not affect the reliability of our results and we confirmed the usability of this method for this genus.
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Morphological analysis of the hindlimb in apes and humans. I. Muscle architecture.
Payne, R C; Crompton, R H; Isler, K; Savage, R; Vereecke, E E; Günther, M M; Thorpe, S K S; D'Août, K
2006-06-01
We present quantitative data on the hindlimb musculature of Pan paniscus, Gorilla gorilla gorilla, Gorilla gorilla graueri, Pongo pygmaeus abelii and Hylobates lar and discuss the findings in relation to the locomotor habits of each. Muscle mass and fascicle length data were obtained for all major hindlimb muscles. Physiological cross-sectional area (PCSA) was estimated. Data were normalized assuming geometric similarity to allow for comparison of animals of different size/species. Muscle mass scaled closely to (body mass)(1.0) and fascicle length scaled closely to (body mass)(0.3) in most species. However, human hindlimb muscles were heavy and had short fascicles per unit body mass when compared with non-human apes. Gibbon hindlimb anatomy shared some features with human hindlimbs that were not observed in the non-human great apes: limb circumferences tapered from proximal-to-distal, fascicle lengths were short per unit body mass and tendons were relatively long. Non-human great ape hindlimb muscles were, by contrast, characterized by long fascicles arranged in parallel, with little/no tendon of insertion. Such an arrangement of muscle architecture would be useful for locomotion in a three dimensionally complex arboreal environment.
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Population viability of Arctic grayling in the Gibbon River, Yellowstone National Park
Steed, Amber C.; Zale, Alexander V.; Koel, Todd M.; Kalinowski, Steven T.
2010-01-01
The fluvial Arctic grayling Thymallus arcticus is restricted to less than 5% of its native range in the contiguous United States and was relisted as a category 3 candidate species under the U.S. Endangered Species Act in 2010. Although fluvial Arctic grayling of the lower Gibbon River, Yellowstone National Park, Wyoming, were considered to have been extirpated by 1935, anglers and biologists have continued to report catching low numbers of Arctic grayling in the river. Our goal was to determine whether a viable population of fluvial Arctic grayling persisted in the Gibbon River or whether the fish caught in the river were downstream emigrants from lacustrine populations in headwater lakes. We addressed this goal by determining relative abundances, sources, and evidence for successful spawning of Arctic grayling in the Gibbon River. During 2005 and 2006, Arctic grayling comprised between 0% and 3% of the salmonid catch in riverwide electrofishing (mean Back-calculated lengths at most ages were similar among all fish, and successful spawning within the Gibbon River below the headwater lakes was not documented. Few Arctic grayling adults and no fry were detected in the Gibbon River, implying that a reproducing fluvial population does not exist there. These findings have implications for future Endangered Species Act considerations and management of fluvial Arctic grayling within and outside of Yellowstone National Park. Our comprehensive approach is broadly applicable to the management of sparsely detected aquatic species worldwide.
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Energy Technology Data Exchange (ETDEWEB)
Nutini, Irene
2017-09-20
A short overview of the Liquid Argon In A Testbeam (LArIAT) experiment hosted at Fermilab is reported. This program supports the Liquid Argon Time Projection Chamber (LArTPC) Neutrino Experiments at Fermilab. The LArIAT program consists of a calibration of a LArTPC in a dedicated charged particle beamline. The first total pion interaction cross section measurement ever made on argon is presented here (preliminary result).
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Cheyne, Susan M; Höing, Andrea; Rinear, John; Sheeran, Lori K
2012-01-01
Primates spend a significant proportion of their lives at sleeping sites: the selection of a secure and stable sleeping tree can be crucial for individual survival and fitness. We measured key characteristics of all tree species in which agile gibbons slept, including exposure of the tree crown, root system, height, species and presence of food. Gibbons most frequently slept in Dipterocarpaceae and Fabaceae trees and preferentially chose trees taller than average, slept above the mean canopy height and showed a preference for liana-free trees. These choices could reflect avoidance of competition with other frugivores, but we argue these choices reflect gibbons prioritizing avoidance of predation. The results highlight that gibbons are actively selecting and rejecting sleeping trees based on several characteristics. The importance of the presence of large trees for food is noted and provides insight into gibbon antipredatory behaviour. Copyright © 2013 S. Karger AG, Basel.
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Iyat Sudrajat; Tutut Sunarminto; TB Unu Nitibaskara
2017-01-01
Development of Ecotourism Program at Mandalawangi Resort of Mount Gede Pangrango National Park (TNGGP) is done by optimizing the supply of tourist collaborated with tourist demand. Tourism resource most interesting at Resort Mandalawangi namely Puncak Gunung Gede - Pangrango then others are rare animals such as Leopards java (Panthera pardus) is the key species and Javan Gibbon (Hylobates Molloch) as a flagship species, as well as waterfalls, crater, Blue Lake, and Gayonggong Swamp. Social an...
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Siber Saldırılar Siber Savaşlar ve Etkileri
Kara, Mahruze
2013-01-01
74 pages. İnternetin ortaya çıkması ile yararlarından faydalanılmaktadır. Ancak internetin zararları da mevcuttur. İnternet, dünya dengelerini değiştirmektedir. İnternet, siber saldırılara ve siber savaşlara aracılık eden bir alan olmuştur. Siber saldırılar, ülkelerin ulusal ve ekonomik güvenliğini sarsmaktadır. Siber savaşlar 5. boyutta yapılmaktadır. Bu çalışmada siber silahlar ile siber saldırılar ve siber savaşların etkileri işlenmiştir. Siber güvenlik önlemleri için çöz...
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Zhang, Dao; Fei, Han-Lan; Yuan, Sheng-Dong; Sun, Wen-Mo; Ni, Qing-Yong; Cui, Liang-Wei; Fan, Peng-Fei
2014-04-01
Generally, food abundance and distribution exert important influence on primate ranging behavior. Hoolock gibbons (genus Hoolock) live in lowland and montane forests in India, Bangladesh, Myanmar and China. All information about hoolock gibbons comes from studies on western hoolock gibbons (Hoolock hoolock) living in lowland forest. Between August 2010 and September 2011, we studied the ranging behavior of one habituated group of eastern hoolock gibbon (H. leuconedys) living in a seasonal montane forest in Gaoligongshan, Yunnan, China. Results show that the study group did not increase foraging effort, calculated in this study as the daily path length, when fruit was less available. Instead, the gibbons fed more on leaves and decreased traveling to conserve energy. They relied heavily on a single food species in most study months which was patchily distributed within their total (14-month) home range, and during most months they used only a small portion of their total home range. In order to find enough food, the group shifted its monthly home range according to the seasonal availability of food species. To satisfy their annual food requirements, they occupied a total home range of 93 ha. The absence of neighboring groups of gibbons and the presence of tsaoko cardamom (Amomum tsaoko) plantations may also have influenced the ranging behavior of the group. Further long-term studies of neighboring groups living in intact forests are required to assess these effects.
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International Nuclear Information System (INIS)
Zheng Chunlong; Qiang Jiye; Wang Shaohua
2010-01-01
In the paper, the variable separation approach, homoclinic test technique and bilinear method are successfully extended to a (1 + 1)-dimensional Caudry-Dodd-Gibbon-Sawada-Kortera (CDGSK) system, respectively. Based on the derived exact solutions, some significant types of localized excitations such as standing waves, periodic waves, solitary waves are simultaneously derived from the (1 + 1)-dimensional Caudry-Dodd-Gibbon-Sawada-Kortera system by entrancing appropriate parameters. (general)
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DEFF Research Database (Denmark)
Nielsen, Lisbeth Overgaard
2007-01-01
Afhandlingen undersøger Lars von Triers filmæstetik, som den kommer til udtryk i spillefilmene fra perioden 1984-2007. Afhandlingen analyserer de enkelte films stil, virkningsstrategi og betydningsdannelse.......Afhandlingen undersøger Lars von Triers filmæstetik, som den kommer til udtryk i spillefilmene fra perioden 1984-2007. Afhandlingen analyserer de enkelte films stil, virkningsstrategi og betydningsdannelse....
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Euroopa majanduste andunud vikatimees Lars Christensen / Piret Reiljan
Reiljan, Piret, 1983-
2007-01-01
Danske Banki vanemanalüütik Lars Christensen on kahtluse alla seadnud Eesti valuutakomitee süsteemi püsimise. Vt. samas: Lars Christensen; Valik Lars Christenseni tänavusi hävitavaid hinnanguid Euroopa murelastele; Islandile kuulutatud häving kukutas otsemaid aktsiaid ja valuutat. Kommenteerivad Lars Rasmussen, Flemming Christensen ja Hanna Strandgaard
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McGibbon Syndrome: A report of three siblings
Directory of Open Access Journals (Sweden)
J Maria Rajathi
2013-01-01
Full Text Available Amelogenesis Imperfecta (AI is a collective term for a number of developmental conditions characterized by abnormal enamel formation. Only a few cases of AI have been reported to occur in association with syndromes and metabolic conditions. McGibbon Syndrome or AI and Nephrocalcinosis Syndrome are such disorders with defective enamel and renal calcifications. Early diagnosis of this condition is essential to prevent renal failure and death of the patient.
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Sagittal crest formation in great apes and gibbons.
Balolia, Katharine L; Soligo, Christophe; Wood, Bernard
2017-06-01
The frequency of sagittal crest expression and patterns of sagittal crest growth and development have been documented in hominoids, including some extinct hominin taxa, and the more frequent expression of the sagittal crest in males has been traditionally linked with the need for larger-bodied individuals to have enough attachment area for the temporalis muscle. In the present study, we investigate sagittal cresting in a dentally mature sample of four hominoid taxa (Pan troglodytes schweinfurthii, Gorilla gorilla gorilla, Pongo pygmaeus pygmaeus and Hylobates lar). We investigate whether sagittal crest size increases with age beyond dental maturity in males and females of G. g. gorilla and Po. pyg. pygmaeus, and whether these taxa show sex differences in the timing of sagittal crest development. We evaluate the hypothesis that the larger sagittal crest of males may not be solely due to the requirement for a larger surface area than the un-crested cranial vault can provide for the attachment of the temporalis muscle, and present data on sex differences in temporalis muscle attachment area and sagittal crest size relative to cranial size. Gorilla g. gorilla and Po. pyg. pygmaeus males show significant relationships between tooth wear rank and sagittal crest size, and they show sagittal crest size differences between age groups that are not found in females. The sagittal crest emerges in early adulthood in the majority of G. g. gorilla males, whereas the percentage of G. g. gorilla females possessing a sagittal crest increases more gradually. Pongo pyg. pygmaeus males experience a three-fold increase in the number of specimens exhibiting a sagittal crest in mid-adulthood, consistent with a secondary growth spurt. Gorilla g. gorilla and Po. pyg. pygmaeus show significant sex differences in the size of the temporalis muscle attachment area, relative to cranial size, with males of both taxa showing positive allometry not shown in females. Gorilla g
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LAr instrumentation for Gerda phase II
Energy Technology Data Exchange (ETDEWEB)
Wegmann, Anne [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Collaboration: GERDA-Collaboration
2015-07-01
Gerda is an experiment to search for the neutrinoless double beta decay of {sup 76}Ge. Results of Phase I have been published in summer 2013. Currently the commissioning of Gerda Phase II is ongoing. To reach the aspired background index of ≤10{sup -3} cts/(keV.kg.yr) active background-suppression techniques will be applied, including an active liquid argon veto (LAr veto). It has been demonstrated by the LArGe test facility that the detection of argon scintillation light can be used to effectively suppress background events in the germanium, which simultaneously deposit energy in LAr. The light instrumentation consisting of photomultiplier tubes (PMT) and wavelength-shifting fibers connected to silicon multipliers (SiPM) has been installed in Gerda. In this talk the low background design of the LAr veto and its performance during the commissioning runs are reported.
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The ecology of white-handed and pileated gibbons in a zone of overlap and hybridization in Thailand.
Asensio, Norberto; José-Domínguez, Juan Manuel; Kongrit, Chalita; Brockelman, Warren Y
2017-08-01
The study of related species in contact zones can elucidate what factors mediate species coexistence and geographical distributions. We investigated niche overlap and group interactions of two gibbon species and their hybrids co-occurring in a zone of overlap and hybridization. The location, composition and behavior of white-handed, pileated, and mixed-species gibbon groups were studied by following them during 31 consecutive months in a relatively large part of the contact zone. Twenty groups of white-handed gibbon were mapped followed by nine groups of pileated gibbons and five mixed-species groups. White-handed, pileated and mixed-species groups had similar sizes and composition, ate a high proportion of fruits, shared a large number of species in their diets, and presented similar habitat preferences. Group home range sizes did not differ between species and overlapped little with neighboring groups irrespective of species, and intraspecific and interspecific encounter rates were similar. Ecological similarities support that competition between the gibbon species exists and takes the form of interspecific territoriality. However, we could not find any clear mechanism of niche partitioning favoring coexistence between species. Our findings suggest that the contact zone is unstable and is maintained by dispersal inward from groups of the parental species. The relatively low numbers of mixed-species groups and hybrids found suggests a high degree of premating reproductive isolation, perhaps mediated by interspecific miscommunication. The existence of hybrids and backcrosses potentially undetectable from phenotypic characters alone raises the possibility of more widespread introgression than has been evident. Hence, while interspecific territoriality should reduce the rate of gene transfer, it would not necessarily present a barrier to introgression into contiguous populations of the opposite species. © 2017 Wiley Periodicals, Inc.
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Emergent Synapse Organizers: LAR-RPTPs and Their Companions.
Han, K A; Jeon, S; Um, J W; Ko, J
2016-01-01
Leukocyte common antigen-related receptor tyrosine phosphatases (LAR-RPTPs) have emerged as key players that organize various aspects of neuronal development, including axon guidance, neurite extension, and synapse formation and function. Recent research has highlighted the roles of LAR-RPTPs at neuronal synapses in mediating distinct synaptic adhesion pathways through interactions with a host of extracellular ligands and in governing a variety of intracellular signaling cascades through binding to various scaffolds and signaling proteins. In this chapter, we review and update current research progress on the extracellular ligands of LAR-RPTPs, regulation of their extracellular interactions by alternative splicing and heparan sulfates, and their intracellular signaling machineries. In particular, we review structural insights on complexes of LAR-RPTPs with their various ligands. These studies lend support to general molecular mechanisms underlying LAR-RPTP-mediated synaptic adhesion and signaling pathways. Copyright © 2016 Elsevier Inc. All rights reserved.
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Non-specific alarm calls trigger mobbing behavior in Hainan gibbons (Nomascus hainanus).
Deng, Huaiqing; Gao, Kai; Zhou, Jiang
2016-09-30
Alarm calls are important defensive behaviors. Here, we report the acoustic spectrum characteristics of alarm calls produced by Hainan gibbons (Nomascus hainanus) inhabiting Bawangling National Nature Reserve in Hainan, China. Analysis of call data collected from 2002-2014 shows that alarm calls are emitted by all family group members, except infants. Alarm behavior included simple short alarming calls (7-10 min) followed by longer variable-frequency mobbing calls lasting 5-12 min. The duration of individual alarming and mobbing calls was 0.078 ± 0.014 s and 0.154 ± 0.041 s at frequency ranges of 520-1000 Hz and 690-3920 Hz, respectively. Alarming call duration was positively associated with group size. The alarm calls can trigger mobbing behavior in Hainan gibbons; this is a defense way of social animals, and first report among the primates' species. The system of vocal alarm behavior described in this critically endangered species is simple and effective.
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Bach, Thanh H; Chen, Jin; Hoang, Minh D; Beng, Kingsly C; Nguyen, Van T
2017-08-01
The southern yellow-cheeked crested gibbon (Nomascus gabriellae), an endangered species native to Vietnam and Cambodia, lives exclusively in undisturbed tropical forests and depends primarily on ripe fruit for food. Although this species is highly threatened, its ecology and conservation status remain relatively unknown. In order to understand how this heavily frugivorous primate adapts to the seasonal fluctuation of fruit resources in the forest, we collected feeding behavior and ranging activity data on one group of southern yellow-cheeked crested gibbons in Cat Tien National Park, Vietnam, over 1-year period. We compared these data to information on phenological patterns at the site gleaned during a prior study. We found that the gibbons gathered most of their food from 69 different plant species and also consumed insects and bird eggs. Fruits were the main dietary item (43.3%), followed by leaves (38.4%), flowers (11.6%), and other plant parts (6.0%). A significant seasonal shift in diet was observed; fruit generally dominated the diet in the rainy season and leaves in the dry season. The gibbons often started daily activities very early (05:10 am) in the morning and also ended quite early (16:45 pm) in the afternoon. Socializing was concentrated in the early morning, feeding had a bimodal pattern of high activity levels in mid-morning and mid-afternoon, and resting was most intense at the earliest and latest hours of the day and at midday, with proportionally less time used for traveling at these times. Averaged over the annual cycle, the gibbons spent 45% of their time feeding, 31.9% resting, 14.1% traveling, and 9.0% socializing. The percentage of time allocated to different activities varied significantly across months and between the dry and rainy seasons. Monthly variation in the activity budget was strongly related to changes in diet. In the rainy season, when the gibbons ate a higher percentage of fruit, they decreased their feeding time, while
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Morphological analysis of the hindlimb in apes and humans. I. Muscle architecture
Payne, RC; Crompton, RH; Isler, K; Savage, R; Vereecke, Evie; Gunther, MM; Thorpe, SKS; D'Aout, K
2006-01-01
We present quantitative data on the hindlimb musculature of Pan paniscus, Gorilla gorilla gorilla, Gorilla gorilla graueri, Pongo pygmaeus abelii and Hylobates lar and discuss the findings in relation to the locomotor habits of each. Muscle mass and fascicle length data were obtained for all major hindlimb muscles. Physiological cross-sectional area (PCSA) was estimated. Data were normalized assuming geometric similarity to allow for comparison of animals of different size/species. Muscle mas...
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Directory of Open Access Journals (Sweden)
PUDJI ASTUTI
2006-06-01
Full Text Available The aims of this research were to determine diurnal patterns of testosterone and cortisol metabolites to predict the testis functional status. In this study, fecal testosterone and cortisol were quantified in 77 samples from three male Hylobates moloch during a course of three months period. These data showed that the highest concentration of fecal testosterone occured at 18.00-06.00 (23.61 ng/g dried feces, then declined gradually. The lowest concentration was in the evening (5.54 ng/g dried feces. Our tests showed that there was a decrease in the mean testosterone concentration from 06.00-10.00 to 10.00-14.00 to 14.00-18.00. For cortisol, the highest concentration occured at 06.00-10.00 (597.84 ng/g dried feces, then decline gradually in the evening (225.73 ng/g dried feces.
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Directory of Open Access Journals (Sweden)
A. Kumar
2009-04-01
Full Text Available A survey on the present distribution, population status and conservation of Western Hoolock Gibbon (Hoolock hoolock was conducted from September 2006 to April 2007 in Namdapha National Park, Arunachal Pradesh, northeastern India. The data were recorded from 12 localities in the Park: Gibbon land, Baghnallah, Deban, 15th Mile, 16th Mile, Hawaghar, 19th Mile, Haldibari, Hornbill camp, Baranallah, Firmbase camp, and Embyong. A total of 50 individuals in 20 groups were recorded during the census by using direct and indirect methods. Out of 20 groups, nine groups were observed through direct visual observation. The remaining 11 groups were estimated by using indirect observation methods such as songs, calls, and branch shaking. The composition of the population was 19 adult males (38%, 19 adult females (38%, and 12 immatures (24%. The group size was estimated as 2.5 individuals per group. Anthropogenic disturbances observed in the gibbon habitat were habitat loss, hunting and poaching, canopy gaps, livelihood issues for local people, and livestock grazing.
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Geographic and species association of hepatitis B virus genotypes in non-human primates
International Nuclear Information System (INIS)
Starkman, S.E.; MacDonald, D.M.; Lewis, J.C.M.; Holmes, E.C.; Simmonds, P.
2003-01-01
Infection with hepatitis B virus (HBV) has been detected in human populations throughout the world, as well as in a number of ape species (Pan troglodytes, Gorilla gorilla, gibbons [Nomascus and Hylobates species] and Pongo pygmaeus). To investigate the distribution of naturally occurring HBV infection in these species and other African Old World monkey species (Cercopithecidae), we screened 137 plasma samples from mainly wild caught animals by polymerase chain reaction (PCR) using several of highly conserved primers from the HB surface (HBs) gene, and for HBs antigen (HBsAg) by ELISA. None of the 93 Cercopithecidae screened (6 species) showed PCR or serology evidence for HBV infection; in contrast 2 from 8 chimpanzees and 5 from 22 gibbons were PCR-positive with each set of primers. Complete genome sequences from each of the positive apes were obtained and compared with all previously published complete and surface gene sequences. This extended phylogenetic analysis indicated that HBV variants from orangutans were interspersed by with HBV variants from southerly distributed gibbon species (H. agilis and H. moloch) occupying overlapping or adjacent habitat ranges with orangutans; in contrast, HBV variants from gibbon species in mainland Asia were phylogenetically distinct. A geographical rather than (sub)species association of HBV would account for the distribution of HBV variants in different subspecies of chimpanzees in Africa, and explain the inlier position of the previously described lowland gorilla sequence in the chimpanzee clade. These new findings have a number of implication for understanding the origins and epidemiology of HBV infection in non-human primates
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Enformasyon Toplumunun Suçluları: “Hacker”lar
Emre Kaya, Ayşe Elif
2018-01-01
Bu çalışmada, 1960’lı yıllarda araştırmacılar tarafından ortaya konan enformasyon toplumu projeleri ile aynı dönemde ortaya çıkan “hacker”lar ve “hacker”ların suça yöneliş nedenleri üzerinde durulmaktadır. Çalışmada, enformasyon projeleri ve ona kar- şılık sunulan eleştiriler ortaya konularak, “hacker”ların eylemlerinin enformasyon toplumu projelerine yönelik bir eleştiriyi içlerinde barındırıp barındırmadıkları sorusu araştırılmıştır. Kapsamı bu şekilde be...
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The Liquid Annular Reactor System (LARS) propulsion
International Nuclear Information System (INIS)
Powell, J.; Ludewig, H.; Horn, F.; Lenard, R.
1990-01-01
A concept for very high specific impulse (greater than 2000 seconds) direct nuclear propulsion is described. The concept, termed the liquid annular reactor system (LARS), uses liquid nuclear fuel elements to heat hydrogen propellant to very high temperatures (approximately 6000 K). Operating pressure is moderate (approximately 10 atm), with the result that the outlet hydrogen is virtually 100 percent dissociated to monatomic H. The molten fuel is contained in a solid container of its own material, which is rotated to stabilize the liquid layer by centripetal force. LARS reactor designs are described, together with neutronic and thermal-hydraulic analyses. Power levels are on the order of 200 megawatts. Typically, LARS designs use seven rotating fuel elements, are beryllium moderated, and have critical radii of approximately 100 cm (core L/D approximately equal to 1.5)
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ICARUS An Innovative Large LAR Detector for Neutrino Physics
Vignoli, C; Disdier, J.M.; Rampoldi, D.; Passardi, G.
2006-01-01
ICARUS is an international project that foresees the installation of very large LAr detectors inside the Gran Sasso underground laboratory in order to be sensitive to rare phenomena of particle physics. The detection technique is based on the collection of electrons produced by particle interactions in LAr by a matrix of thousands of thin wires. At the moment the project foresees the installation of a 600,000‐kg vessel (T600). The total amount of LAr can be expanded in a modular way to masses of the order of 106 kg. The T600 houses two identical 300,000‐kg Ar sub‐cryostats that are aluminum boxes about 20‐m long, 4‐m high and 4‐m wide. Safety requirements for the underground installation have led to a unique design for the vessels to prevent LAr spillages even in the case of inner cryostat failure. Electrons must drift over meters requiring the development of special gas and liquid Ar purification units to provide an extremely high LAr purity (better then 0.1 ppb). The cooling system has been desi...
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Ülar Mark: loome uut ja iga loomisega lammutame midagi / Ülar Mark ; intervjueerinud Mikk Salu
Mark, Ülar, 1968-
2010-01-01
Eesti Arhitektuurikeskuse juhatuse esimees, arhitekt Ülar Mark Tallinna arhitektuurist ja linna arengust, demokraatlikust linnaruumist. Pikemalt Solarise keskusest, vabadussambast, väikepoodide asemele suurte kaubanduskeskuste tulekust
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Performance of the LAr scintillation veto of GERDA Phase II
Energy Technology Data Exchange (ETDEWEB)
Wiesinger, Christoph [Technische Universitaet Muenchen, Physik Dept. E15, James-Franck-Strasse, 85748 Garching (Germany); Collaboration: GERDA-Collaboration
2015-07-01
Gerda is an experiment to search for the neutrinoless double beta decay in {sup 76}Ge. Results of Phase I have been published in summer 2013 and Gerda is upgraded to Phase II. To reach the aspired background index of ≤ 10{sup -3} cts/(keV.kg.yr) for Phase II active background-suppression techniques are applied, including an active liquid argon (LAr) veto. It has been demonstrated with the LArGe test facility that the detection of argon scintillation light can be used to effectively suppress background events in the germanium, which simultaneously deposit energy in the LAr. The light instrumentation consisting of photomultiplier tubes (PMT) and wavelength-shifting fibers connected to silicon multipliers (SiPM) has been installed in Gerda. In this talk the low background design of the LAr veto and its performance during the commissioning runs are reported.
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Three-dimensional Imaging for Large LArTPCs
Energy Technology Data Exchange (ETDEWEB)
Chao, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Qian, X. [Brookhaven National Lab. (BNL), Upton, NY (United States); Viren, B. [Brookhaven National Lab. (BNL), Upton, NY (United States); Diwan, M. [Brookhaven National Lab. (BNL), Upton, NY (United States)
2017-12-14
High-performance event reconstruction is critical for current and future massive liquid argon time projection chambers (LArTPCs) to realize their full scientic potential. LArTPCs with readout using wire planes provides a limited number of 2D projections. In general, without a pixel-type readout it is challenging to achieve unambiguous 3D event reconstruction. As a remedy, we present a novel 3D imaging method, Wire-Cell, which incorporates the charge and sparsity information in addition to the time and geometry through simple and robust mathematics.
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Thermographic and microscopic evaluation of LARS knee ligament tearing.
Pătraşcu, Jenel Marian; Amarandei, Mihaela; Kun, Karla Noemy; Borugă, Ovidiu; Totorean, Alina; Andor, Bogdan; Florescu, Sorin
2014-01-01
Damage to knee articular ligaments causes important functional problems and adversely affects particularly the stability of the knee joint. Several methods were developed in order to repair damage to the anterior cruciate ligament (ACL), which employ autografts, allografts, as well as synthetic ligaments. One such synthetic scaffold, the ligament advanced reinforcement system (LARS) synthetic ligament is made of non-absorbing polyethylene terephthalate fibers whose structure allow tissue ingrowths in the intra-articular part, improving the stability of the joint. The LARS ligament is nowadays widely used in modern knee surgery in the Europe, Canada, China or Japan. This paper evaluates LARS ligament from two perspectives. The first regards a study done by the Orthopedics Clinic II, Timisoara, Romania, which compared results obtained by employing two techniques of ACL repair - the Bone-Tendon-Bone (BTB) or LARS arthroscopic, intra-articular techniques. This study found that patients treated with the BTB technique presented with an IKDC score of 45.82±1.14 units preoperative, with increasing values in the first nine months after each implant post-surgical ligament restoration, reaching an average value of 75.92 ± 2.88 units postoperative. Patients treated with the LARS technique presented with an IKDC score of 43.64 ± 1.11 units preoperative, and a score of 77.32 ± 2.71 units postoperative. The second perspective describes the thermographic and microscopic analysis of an artificial knee ligament tearing or loosening. The objective of the study was to obtain information regarding the design of artificial ligaments in order to expand their lifespan and avoid complications such as recurring synovitis, osteoarthritis and trauma of the knee joint. Thermographic data has shown that tearing begins from the inside out, thus improving the inner design of the ligament would probably enhance its durability. An optical microscope was employed to obtain images of structural
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Performance of the LAr scintillation veto of Gerda Phase II
Energy Technology Data Exchange (ETDEWEB)
Wiesinger, Christoph [Physik-Department and Excellence Cluster Universe, Technische Universitaet Muenchen, James-Franck-Strasse, 85748 Garching (Germany); Collaboration: GERDA-Collaboration
2016-07-01
Gerda is an experiment to search for the neutrinoless double beta decay in {sup 76}Ge. Results of Phase I have been published in summer 2013 and Gerda has been upgraded to Phase II. To reach the aspired background index of ∝10{sup -3} cts/(keV.kg.yr) for Phase II active background-suppression techniques are applied, including an active liquid argon (LAr) veto. It has been demonstrated with the LArGe test facility that the detection of argon scintillation light can be used to effectively suppress background events in the germanium detectors, which simultaneously deposit energy in the LAr. The light instrumentation consisting of photomultiplier tubes (PMT) and wavelength-shifting fibers connected to silicon photomultipliers (SiPM) has been installed in Gerda. In this talk the low background design of the LAr veto and its performance during Phase II start-up is reported.
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LArSoft: toolkit for simulation, reconstruction and analysis of liquid argon TPC neutrino detectors
Snider, E. L.; Petrillo, G.
2017-10-01
LArSoft is a set of detector-independent software tools for the simulation, reconstruction and analysis of data from liquid argon (LAr) neutrino experiments The common features of LAr time projection chambers (TPCs) enable sharing of algorithm code across detectors of very different size and configuration. LArSoft is currently used in production simulation and reconstruction by the ArgoNeuT, DUNE, LArlAT, MicroBooNE, and SBND experiments. The software suite offers a wide selection of algorithms and utilities, including those for associated photo-detectors and the handling of auxiliary detectors outside the TPCs. Available algorithms cover the full range of simulation and reconstruction, from raw waveforms to high-level reconstructed objects, event topologies and classification. The common code within LArSoft is contributed by adopting experiments, which also provide detector-specific geometry descriptions, and code for the treatment of electronic signals. LArSoft is also a collaboration of experiments, Fermilab and associated software projects which cooperate in setting requirements, priorities, and schedules. In this talk, we outline the general architecture of the software and the interaction with external libraries and detector-specific code. We also describe the dynamics of LArSoft software development between the contributing experiments, the projects supporting the software infrastructure LArSoft relies on, and the core LArSoft support project.
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ARIADNE, a Photographic LAr TPC at the CERN Neutrino Platform
Mavrokoridis, K; Nessi, M; Roberts, A; Smith, N A; Touramanis, C; CERN. Geneva. SPS and PS Experiments Committee; SPSC
2016-01-01
This letter of intent describes a novel and innovative two-phase LAr TPC with photographic capabilities as an attractive alternative readout method to the currently accepted segmented THGEMs which will require many thousands of charge readout channels for kton-scale two-phase TPCs. These colossal LAr TPCs will be used for the future long-baseline-neutrino-oscillation experiments. Optical readout also presents many other clear advantages over current readout techniques such as ease of scalability, upgrade, installation and maintenance, and cost effectiveness. This technology has already been demonstrated at the Liverpool LAr facility with the photographic capturing of cosmic muon tracks and single gammas using a 40-litre prototype. We have now secured ERC funding to develop this further with the ARIADNE programme. ARIADNE will be a 1-ton two-phase LAr TPC utilizing THGEM and EMCCD camera readouts in order to photograph interactions, allowing for track reconstruction and particle identification. We are request...
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An Efficient Acoustic Density Estimation Method with Human Detectors Applied to Gibbons in Cambodia.
Directory of Open Access Journals (Sweden)
Darren Kidney
Full Text Available Some animal species are hard to see but easy to hear. Standard visual methods for estimating population density for such species are often ineffective or inefficient, but methods based on passive acoustics show more promise. We develop spatially explicit capture-recapture (SECR methods for territorial vocalising species, in which humans act as an acoustic detector array. We use SECR and estimated bearing data from a single-occasion acoustic survey of a gibbon population in northeastern Cambodia to estimate the density of calling groups. The properties of the estimator are assessed using a simulation study, in which a variety of survey designs are also investigated. We then present a new form of the SECR likelihood for multi-occasion data which accounts for the stochastic availability of animals. In the context of gibbon surveys this allows model-based estimation of the proportion of groups that produce territorial vocalisations on a given day, thereby enabling the density of groups, instead of the density of calling groups, to be estimated. We illustrate the performance of this new estimator by simulation. We show that it is possible to estimate density reliably from human acoustic detections of visually cryptic species using SECR methods. For gibbon surveys we also show that incorporating observers' estimates of bearings to detected groups substantially improves estimator performance. Using the new form of the SECR likelihood we demonstrate that estimates of availability, in addition to population density and detection function parameters, can be obtained from multi-occasion data, and that the detection function parameters are not confounded with the availability parameter. This acoustic SECR method provides a means of obtaining reliable density estimates for territorial vocalising species. It is also efficient in terms of data requirements since since it only requires routine survey data. We anticipate that the low-tech field requirements will
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2008-01-01
Emerson 901 TOW Under Armor (TUA) weapons system. When reliably operational, the Emerson 901 turret can still provide effective anti-armor fires as...the rear of the LAV-R thus there is no available space to carry ammunition resupplies, food, or under armor ambulance kits. On the other hand, the...the LAR battalion; however, the LAV-EFSS cannot be fired under armor protection or in the direct firing mode. Both the LAV-120 AMS and the LAV-EFSS
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ICARUS: An Innovative Large LAR Detector for Neutrino Physics
Vignoli, C.; Barni, D.; Disdier, J. M.; Rampoldi, D.; Icarus Collaboration
2006-04-01
ICARUS is an international project that foresees the installation of very large LAr detectors inside the Gran Sasso underground laboratory in order to be sensitive to rare phenomena of particle physics. The detection technique is based on the collection of electrons produced by particle interactions in LAr by a matrix of thousands of thin wires. At the moment the project foresees the installation of a 600,000-kg vessel (T600). The total amount of LAr can be expanded in a modular way to masses of the order of 106 kg. The T600 houses two identical 300,000-kg Ar sub-cryostats that are aluminum boxes about 20-m long, 4-m high and 4-m wide. Safety requirements for the underground installation have led to a unique design for the vessels to prevent LAr spillages even in the case of inner cryostat failure. Electrons must drift over meters requiring the development of special gas and liquid Ar purification units to provide an extremely high LAr purity (better then 0.1 ppb). The cooling system has been designed to assure a high thermal uniformity in the detector volume (less than 1-K differential). The cryogenic system associated with the final ICARUS configuration is based on three N2 refrigerators, three 30-m3 tanks and pump driven two-phase N2 forced-flow cooling of the various sub-systems. The T600 was successfully tested in Pavia in 2001 and it is now under installation in Gran Sasso for final operation. The future mass expansion strategy is under investigation.
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Guan, Zhen-Hua; Huang, Bei; Ning, Wen-He; Ni, Qing-Yong; Sun, Guo-Zheng; Jiang, Xue-Long
2013-12-01
In primates, grooming is considered among the most common behaviors for maintaining social bonds; however, to date, few studies have examined grooming behavior in gibbon species in detail. We used both a 5-min interval scan method and social network analysis to study grooming in two groups of polygynous western black-crested gibbon (Nomascus concolor) in Wuliang Mountain, Central Yunnan, China. Individuals in both groups spent little time in social grooming (1.45% and 1.97% of active time). We compared the two groups' grooming networks and found that the group that maintained a more stable social unit had a more complex grooming network while the group with new immigrants had a grooming network characterized by fewer grooming pairs. Females in both groups played important roles in the grooming network. A newly immigrant female spent the most time grooming others and chose the resident adult female as her main adult grooming partner. Other females from both groups chose the adult male as their primary grooming partner (except their offspring). A sub-adult male who had resided in his natal group for 2 years after maturing into an adult also groomed more and was at the center of the network. This male finally replaced the breeding male in his group 3 years after our data collection period ended. We hypothesize that the immigrant female and the resident young adult male engaged in more extensive grooming interactions as a behavioral strategy to gain tolerance from long-term residents. Our results suggest that female gibbons in polygynous groups actively cooperate in maintaining social relationships rather than co-exist through tolerance or avoidance. Our observations indicate that grooming networks in crested gibbons reflect individual dynamics and partly support the social cohesion hypothesis for primate grooming. In this regard, we suggest that changes in gibbon grooming networks can be used to predict social change. © 2013 Wiley Periodicals, Inc.
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Warhurst, David C; Craig, John C; Raheem, K Saki
2016-01-01
Antimalarial chloroquine (CQ) prevents haematin detoxication when CQ-base concentrates in the acidic digestive vacuole through protonation of its p-aminopyridine (pAP) basic aromatic nitrogen and sidechain diethyl-N. CQ export through the variant vacuolar membrane export channel, PFCRT, causes CQ-resistance in Plasmodium falciparum but 3-methyl CQ (sontochin SC), des-ethyl amodiaquine (DAQ) and bis 4-aminoquinoline piperaquine (PQ) are still active. This is determined by changes in drug accumulation ratios in parasite lipid (LAR) and in vacuolar water (VAR). Higher LAR may facilitate drug binding to and blocking PFCRT and also aid haematin in lipid to bind drug. LAR for CQ is only 8.3; VAR is 143,482. More hydrophobic SC has LAR 143; VAR remains 68,523. Similarly DAQ with a phenol substituent has LAR of 40.8, with VAR 89,366. In PQ, basicity of each pAP is reduced by distal piperazine N, allowing very high LAR of 973,492, retaining VAR of 104,378. In another bis quinoline, dichlorquinazine (DCQ), also active but clinically unsatisfactory, each pAP retains basicity, being insulated by a 2-carbon chain from a proximal nitrogen of the single linking piperazine. While LAR of 15,488 is still high, the lowest estimate of VAR approaches 4.9 million. DCQ may be expected to be very highly lysosomotropic and therefore potentially hepatotoxic. In 11 pAP antimalarials a quadratic relationship between logLAR and logResistance Index (RI) was confirmed, while log (LAR/VAR) vs logRI for 12 was linear. Both might be used to predict the utility of structural modifications.
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The (′/-Expansion Method for Abundant Traveling Wave Solutions of Caudrey-Dodd-Gibbon Equation
Directory of Open Access Journals (Sweden)
Hasibun Naher
2011-01-01
Full Text Available We construct the traveling wave solutions of the fifth-order Caudrey-Dodd-Gibbon (CDG equation by the (/-expansion method. Abundant traveling wave solutions with arbitrary parameters are successfully obtained by this method and the wave solutions are expressed in terms of the hyperbolic, the trigonometric, and the rational functions. It is shown that the (/-expansion method is a powerful and concise mathematical tool for solving nonlinear partial differential equations.
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Directory of Open Access Journals (Sweden)
Jinxia Zhu
2018-03-01
Full Text Available Land acquisition and resettlement (LAR is an important step in urban development. As one of the ‘externalities of development’, LAR conflicts have affected social stability and development in rural areas of China. With social conflict research shifting from value identity to resource allocation, few studies have examined the relationship between the spatial injustice of urban public resources and LAR conflict. To mitigate this research gap and formulate effective policies, this study aims to reinterpret the obstacles of LAR conflicts from the perspective of the spatial injustice of urban public facilities allocation in Hangzhou City by examining 195 administrative litigation cases. Spatial accessibility was used for estimating the spatial justice of urban public resources allocation. A classification and regression tree (CART model was applied to identify the advantage and disadvantage factors behind LAR conflict, and explored the logical and structural relationships among these factors. Results showed that a spatial mismatch between the spatial behavior preferences of human activity and the spatial injustice of urban public resources allocation had significantly accelerated LAR conflicts. When the spatial behavior preferences of human activity and spatial distribution of urban public resources correspond to each other pre- and after LAR, basic rights to social space are safeguarded and various groups can equitably share spatial resources. There are no conflicts. Conversely, respondents expressed a high level of dissatisfaction in comparison to their pre-LAR conditions, and LAR conflict undeniably occurs. This approach also proposes some good LAR policies by regulating the spatial injustice of urban public resources allocation associated with LAR with the aim of long-term urban sustainable development for Hangzhou.
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File list: His.Lar.50.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.50.AllAg.Larval_brain dm3 Histone Larvae Larval brain SRX1426943,SRX1426945... http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.50.AllAg.Larval_brain.bed ...
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File list: His.Lar.10.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.10.AllAg.Larval_brain dm3 Histone Larvae Larval brain SRX1426945,SRX1426943... http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.10.AllAg.Larval_brain.bed ...
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File list: His.Lar.20.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.20.AllAg.Larval_brain dm3 Histone Larvae Larval brain SRX1426943,SRX1426945... http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.20.AllAg.Larval_brain.bed ...
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LArGe. A liquid argon scintillation veto for GERDA
International Nuclear Information System (INIS)
Heisel, Mark
2011-01-01
LArGe is a GERDA low-background test facility to study novel background suppression methods in a low-background environment, for possible applications in the GERDA experiment. GERDA searches for the neutrinoless double-beta decay in 76 Ge, by operating naked germanium detectors submersed into 65 m 3 of liquid argon. Similarly, LArGe runs Ge-detectors in 1 m 3 (1.4 tons) of liquid argon, which in addition is instrumented with photomultipliers to detect argon scintillation light. The light is used in anti-coincidence with the germanium detectors, to effectively suppress background events that deposit energy in the liquid argon. This work adresses the design, construction, and commissioning of LArGe. The background suppression efficiency has been studied in combination with a pulse shape discrimination (PSD) technique for various sources, which represent characteristic backgrounds to GERDA. Suppression factors of a few times 10 3 have been achieved. First background data of LArGe (without PSD) yield a background index of (0.12-4.6).10 -2 cts/(keV.kg.y) (90% c.l.), which is at the level of the Gerda phase I design goal. Furthermore, for the first time we measure the natural 42 Ar abundance (in parallel to Gerda), and have indication for the 2νββ-decay in natural germanium. (orig.)
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LArGe. A liquid argon scintillation veto for GERDA
Energy Technology Data Exchange (ETDEWEB)
Heisel, Mark
2011-04-13
LArGe is a GERDA low-background test facility to study novel background suppression methods in a low-background environment, for possible applications in the GERDA experiment. GERDA searches for the neutrinoless double-beta decay in {sup 76}Ge, by operating naked germanium detectors submersed into 65 m{sup 3} of liquid argon. Similarly, LArGe runs Ge-detectors in 1 m{sup 3} (1.4 tons) of liquid argon, which in addition is instrumented with photomultipliers to detect argon scintillation light. The light is used in anti-coincidence with the germanium detectors, to effectively suppress background events that deposit energy in the liquid argon. This work adresses the design, construction, and commissioning of LArGe. The background suppression efficiency has been studied in combination with a pulse shape discrimination (PSD) technique for various sources, which represent characteristic backgrounds to GERDA. Suppression factors of a few times 10{sup 3} have been achieved. First background data of LArGe (without PSD) yield a background index of (0.12-4.6).10{sup -2} cts/(keV.kg.y) (90% c.l.), which is at the level of the Gerda phase I design goal. Furthermore, for the first time we measure the natural {sup 42}Ar abundance (in parallel to Gerda), and have indication for the 2{nu}{beta}{beta}-decay in natural germanium. (orig.)
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The Liquid Argon Software Toolkit (LArSoft): Goals, Status and Plan
Energy Technology Data Exchange (ETDEWEB)
Pordes, Rush [Fermilab; Snider, Erica [Fermilab
2016-08-17
LArSoft is a toolkit that provides a software infrastructure and algorithms for the simulation, reconstruction and analysis of events in Liquid Argon Time Projection Chambers (LArTPCs). It is used by the ArgoNeuT, LArIAT, MicroBooNE, DUNE (including 35ton prototype and ProtoDUNE) and SBND experiments. The LArSoft collaboration provides an environment for the development, use, and sharing of code across experiments. The ultimate goal is to develop fully automatic processes for reconstruction and analysis of LArTPC events. The toolkit is based on the art framework and has a well-defined architecture to interface to other packages, including to GEANT4 and GENIE simulation software and the Pandora software development kit for pattern recognition. It is designed to facilitate and support the evolution of algorithms including their transition to new computing platforms. The development of the toolkit is driven by the scientific stakeholders involved. The core infrastructure includes standard definitions of types and constants, means to input experiment geometries as well as meta and event- data in several formats, and relevant general utilities. Examples of algorithms experiments have contributed to date are: photon-propagation; particle identification; hit finding, track finding and fitting; electromagnetic shower identification and reconstruction. We report on the status of the toolkit and plans for future work.
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File list: ALL.Lar.50.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.50.AllAg.Larval_brain dm3 All antigens Larvae Larval brain SRX1426944,SRX14...26943,SRX1426945,SRX1426946 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.50.AllAg.Larval_brain.bed ...
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File list: ALL.Lar.20.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.20.AllAg.Larval_brain dm3 All antigens Larvae Larval brain SRX1426944,SRX14...26943,SRX1426945,SRX1426946 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.20.AllAg.Larval_brain.bed ...
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File list: ALL.Lar.05.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.05.AllAg.Larval_brain dm3 All antigens Larvae Larval brain SRX1426945,SRX14...26944,SRX1426946,SRX1426943 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.05.AllAg.Larval_brain.bed ...
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File list: ALL.Lar.10.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.10.AllAg.Larval_brain dm3 All antigens Larvae Larval brain SRX1426945,SRX14...26944,SRX1426943,SRX1426946 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.10.AllAg.Larval_brain.bed ...
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Koda = Koda / Ülar Mark, Kariina Kristiina Kaufmann, Kadri Tonto ; kommenteerinud Katrin Koov
Mark, Ülar, 1968-
2016-01-01
Minimalistliku vormiga eramu KODA Tallinnas, Järvekalda tee 33. Autorid Ülar Mark, Taavi Jakobson, Hannes Tamjärv, Kalev Ramjalg, Marek Strandberg. Arhitektid Ülar Mark, Kariina Kristiina Kaufmann, Kadri Tonto, Hannes Praks
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File list: Oth.Lar.05.daf-12.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.05.daf-12.AllCell ce10 TFs and others daf-12 Larvae SRX146513,SRX065705,SRX...146512,SRX065706,SRX065713,SRX065714 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Lar.05.daf-12.AllCell.bed ...
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File list: Oth.Lar.10.daf-12.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.10.daf-12.AllCell ce10 TFs and others daf-12 Larvae SRX146513,SRX065706,SRX...065705,SRX146512,SRX065713,SRX065714 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Lar.10.daf-12.AllCell.bed ...
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File list: Oth.Lar.50.daf-12.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.50.daf-12.AllCell ce10 TFs and others daf-12 Larvae SRX065714,SRX065713,SRX...146512,SRX065705,SRX146513,SRX065706 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Lar.50.daf-12.AllCell.bed ...
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File list: Oth.Lar.20.daf-12.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.20.daf-12.AllCell ce10 TFs and others daf-12 Larvae SRX146513,SRX146512,SRX...065713,SRX065705,SRX065706,SRX065714 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Lar.20.daf-12.AllCell.bed ...
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Regionaalpoliitika ja arhitektuur / Ülar Mark
Mark, Ülar
1999-01-01
Kagu-Eesti Regionaalarengu Programmi raames Eesti Kunstiakadeemia arhitektuurikateedri IV kursuse eriala valikaines 1998/99 tehtud tööst "HyperMobiilne Reaalsus & Kagu Eesti" (juhendajad Ralf Tamm, Ülar Mark). Ühises töös osalesid Tartu Ülikooli geograafiatudengid (juhendaja Rein Ahas). 4 illustratsiooni
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File list: Pol.Lar.50.RNA_polymerase_III.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.50.RNA_polymerase_III.AllCell ce10 RNA polymerase RNA polymerase III Larvae... http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Lar.50.RNA_polymerase_III.AllCell.bed ...
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File list: Pol.Lar.20.RNA_polymerase_III.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.20.RNA_polymerase_III.AllCell ce10 RNA polymerase RNA polymerase III Larvae... http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Lar.20.RNA_polymerase_III.AllCell.bed ...
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File list: Pol.Lar.10.RNA_polymerase_III.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.10.RNA_polymerase_III.AllCell ce10 RNA polymerase RNA polymerase III Larvae... http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Lar.10.RNA_polymerase_III.AllCell.bed ...
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File list: Pol.Lar.05.RNA_polymerase_III.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.05.RNA_polymerase_III.AllCell ce10 RNA polymerase RNA polymerase III Larvae... http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Lar.05.RNA_polymerase_III.AllCell.bed ...
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Matlab implementation of LASSO, LARS, the elastic net and SPCA
DEFF Research Database (Denmark)
2005-01-01
There are a number of interesting variable selection methods available beside the regular forward selection and stepwise selection methods. Such approaches include LASSO (Least Absolute Shrinkage and Selection Operator), least angle regression (LARS) and elastic net (LARS-EN) regression. There al...... exists a method for calculating principal components with sparse loadings. This software package contains Matlab implementations of these functions. The standard implementations of these functions are available as add-on packages in S-Plus and R....
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File list: Pol.Lar.05.RNA_Polymerase_II.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.05.RNA_Polymerase_II.AllCell ce10 RNA polymerase RNA Polymerase II Larvae h...ttp://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Lar.05.RNA_Polymerase_II.AllCell.bed ...
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Investigation and development of the suppression methods of the {sup 42}K background in LArGe
Energy Technology Data Exchange (ETDEWEB)
Lubashevskiy, Alexey [Max-Planck-Institut fuer Kernphysik, Saupfercheckweg 1, D-69117 Heidelberg (Germany); Collaboration: GERDA-Collaboration
2013-07-01
GERDA is an ultra-low background experiment aimed for the neutrinoless double beta decay search. The search is performed using HPGe detectors operated in liquid argon (LAr). One of the most dangerous backgrounds in GERDA is the background from {sup 42}K which is a daughter isotope of cosmogenically produced {sup 42}Ar. {sup 42}K ions are collected towards to the detector by the electric field of the detector. Estimation of the background contribution and development of the suppression methods were performed in the low background test facility LArGe. For this purpose encapsulated HPGe and bare BEGe detectors were operated in 1m{sup 3} of LAr in the LArGe setup. It is equipped with scintillation veto, so particles which deposit part of their energy in LAr can be detected by 9 PMTs. In order to better understand background and to increase statistics the LAr of LArGe was spiked with specially produced {sup 42}Ar. All these investigations allowed us to estimate background contribution from {sup 42}K and demonstrate the possibility to suppress it in future measurements in GERDA Phase II.
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Directory of Open Access Journals (Sweden)
Iratxe Fresneda Delgado
2013-04-01
Full Text Available El presente artículo analiza el modo en el que Lars von Trier recrea para el cine el estereotipo de Medea. Mediante el análisis fílmico de la película y apoyándose en los estudios culturales, el texto se interroga acerca de la importancia y el poder potencial del cine a la hora recuperar el antiguo mito y demostrar su vigencia. El análisis amplía horizontes para la compresión de los mecanismos que articulan el entramado de significados de la película, donde Von Trier aporta una nueva visión del arquetipo de Medea uniéndola, a la tradición pictórica del Romanticismo. Una influencia que habita en las posteriores obras del director danés, donde el paisaje, la naturaleza, se erige en elemento catalizador de las pulsiones humanas, en su cómplice y testigo.This paper explores the way that Lars von Trier’s film recreates the stereotype of Medea. Using film analysis and based on cultural studies the article asks about the importance and potential power of cinema to recover the ancient myth and show their effects. The analysis expands horizons for the understanding of the mechanisms that link the network of meanings of the film, where the author offers a new vision of Medea's archetype attaching it to the pictorial tradition tied to the Romanticism. An influence that can be seen in the later works of Lars von Trier, where the landscape, the nature, stands as a catalyst of human drives, as his accomplice and witness.
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File list: InP.Lar.10.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.10.AllAg.Larval_brain dm3 Input control Larvae Larval brain SRX1426944,SRX1...426946 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.10.AllAg.Larval_brain.bed ...
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File list: InP.Lar.50.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.50.AllAg.Larval_brain dm3 Input control Larvae Larval brain SRX1426944,SRX1...426946 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.50.AllAg.Larval_brain.bed ...
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File list: InP.Lar.05.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.05.AllAg.Larval_brain dm3 Input control Larvae Larval brain SRX1426944,SRX1...426946 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.05.AllAg.Larval_brain.bed ...
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File list: InP.Lar.20.AllAg.Larval_brain [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.20.AllAg.Larval_brain dm3 Input control Larvae Larval brain SRX1426944,SRX1...426946 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.20.AllAg.Larval_brain.bed ...
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File list: InP.Lar.05.Input_control.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.05.Input_control.AllCell ce10 Input control Input control Larvae SRX331089,...,SRX015099 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/InP.Lar.05.Input_control.AllCell.bed ...
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File list: Oth.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.50.AllAg.3rd_instar dm3 TFs and others Larvae 3rd instar SRX318781,SRX31878...5306 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Lar.50.AllAg.3rd_instar.bed ...
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Warwick, Peter D.; Crowley, Sharon S.; Ruppert, Leslie F.; Pontolillo, James
1997-01-01
This study examined the petrographic and geochemical characteristics of two lignite beds (3500 and 4500 beds, Manning Formation, Jackson Group, Eocene) that are mined at the Gibbons Creek mine in east-central Texas. The purpose of the study was to identify the relations among sample ash yield, coal petrography, and trace-element concentrations in lignite and adjoining rock layers of the Gibbons Creek mine. Particular interest was given to the distribution of 12 environmentally sensitive trace elements (As, Be, Cd, Cr, Co, Hg, Mn, Ni, Pb, Sb, Se, and U) that have been identified as potentially hazardous air pollutants (HAPs) in the United States Clean Air Act Amendments of 1990. Eleven lignite, floor, and rock parting samples were collected from incremental channel samples of the 3500 and 4500 beds that were exposed in a highwall of pit A3 at the Gibbons Creek mine. Short proximate and ultimate and forms of sulfur analyses were performed on all lignite samples, and lignite and rock samples were analyzed for 60 major, minor and trace elements. Representative splits of all lignite samples were ground and cast into pellets, and polished for petrographic analyses in blue-light fluorescence and reflected white light to determine liptinite, inertinite, and huminite maceral group percentages. The following observations summarize our results and conclusions about the geochemistry, petrography, and sedimentology of the 3500 and 4500 beds of the Gibbons Creek lignite deposit: (1) Weighted average dry (db) ash yield for the two beds is 29.7%, average total sulfur content is 2.6%, and average calorific value is 7832 Btu (18.22 MJ/kg). Ash yields are greatest in the lower bench (59.33% db) of the 3500 bed and in the upper bench of the 4500 bed (74.61% db). (2) For lignite samples (on a whole-coal basis), the distributions of two of the HAPs (Pb and Sb) are positively related to ash yield, probably indicating an inorganic affinity for these elements. By using cluster analysis we
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Cardiopulmonary bypass: development of John Gibbon's heart-lung machine
Directory of Open Access Journals (Sweden)
Andréia Cristina Passaroni
2015-04-01
Full Text Available AbstractObjective:To provide a brief review of the development of cardiopulmonary bypass.Methods:A review of the literature on the development of extracorporeal circulation techniques, their essential role in cardiovascular surgery, and the complications associated with their use, including hemolysis and inflammation.Results:The advancement of extracorporeal circulation techniques has played an essential role in minimizing the complications of cardiopulmonary bypass, which can range from various degrees of tissue injury to multiple organ dysfunction syndrome. Investigators have long researched the ways in which cardiopulmonary bypass may insult the human body. Potential solutions arose and laid the groundwork for development of safer postoperative care strategies.Conclusion:Steady progress has been made in cardiopulmonary bypass in the decades since it was first conceived of by Gibbon. Despite the constant evolution of cardiopulmonary bypass techniques and attempts to minimize their complications, it is still essential that clinicians respect the particularities of each patient's physiological function.
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File list: Oth.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.10.AllAg.3rd_instar dm3 TFs and others Larvae 3rd instar SRX104963,SRX10497...4971,SRX331403 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Lar.10.AllAg.3rd_instar.bed ...
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File list: Oth.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.20.AllAg.3rd_instar dm3 TFs and others Larvae 3rd instar SRX318781,SRX31878...1403,SRX495243 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Lar.20.AllAg.3rd_instar.bed ...
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File list: Oth.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.05.AllAg.3rd_instar dm3 TFs and others Larvae 3rd instar SRX104964,SRX10496...1403,SRX495243 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Lar.05.AllAg.3rd_instar.bed ...
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File list: InP.Lar.20.Input_control.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.20.Input_control.AllCell dm3 Input control Input control Larvae SRX040614,S...457599,SRX1426944,SRX1426946,SRX1426948 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.20.Input_control.AllCell.bed ...
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File list: His.Lar.05.AllAg.1st_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.05.AllAg.1st_instar dm3 Histone Larvae 1st instar SRX013088,SRX013009,SRX01...3064,SRX013044,SRX013097 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.05.AllAg.1st_instar.bed ...
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File list: Pol.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.10.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287908,SRX28790...7,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.10.AllAg.3rd_instar.bed ...
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File list: His.Lar.20.AllAg.1st_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.20.AllAg.1st_instar dm3 Histone Larvae 1st instar SRX013009,SRX013088,SRX01...3044,SRX013064,SRX013097 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.20.AllAg.1st_instar.bed ...
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File list: Pol.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.50.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287908,SRX28790...7,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.50.AllAg.3rd_instar.bed ...
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File list: ALL.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.50.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX1038029,SRX103803...SRX467060,SRX495306,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.50.AllAg.3rd_instar.bed ...
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File list: Pol.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.05.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287907,SRX28790...8,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.05.AllAg.3rd_instar.bed ...
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File list: His.Lar.50.AllAg.1st_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.50.AllAg.1st_instar dm3 Histone Larvae 1st instar SRX013009,SRX013088,SRX01...3044,SRX013064,SRX013097 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.50.AllAg.1st_instar.bed ...
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File list: His.Lar.10.AllAg.1st_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.10.AllAg.1st_instar dm3 Histone Larvae 1st instar SRX013088,SRX013064,SRX01...3044,SRX013009,SRX013097 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.10.AllAg.1st_instar.bed ...
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File list: Pol.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.20.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287908,SRX28790...7,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.20.AllAg.3rd_instar.bed ...
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File list: InP.Lar.05.Input_control.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.05.Input_control.AllCell dm3 Input control Input control Larvae SRX645428,S...287678,SRX1426944,SRX1426946,SRX1426948,SRX1426950 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.05.Input_control.AllCell.bed ...
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File list: His.Lar.10.AllAg.2nd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.10.AllAg.2nd_instar dm3 Histone Larvae 2nd instar SRX013087,SRX013015,SRX01...3112,SRX013042,SRX013043,SRX013096 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.10.AllAg.2nd_instar.bed ...
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File list: His.Lar.05.AllAg.2nd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.05.AllAg.2nd_instar dm3 Histone Larvae 2nd instar SRX013087,SRX013096,SRX01...3043,SRX013015,SRX013112,SRX013042 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.05.AllAg.2nd_instar.bed ...
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File list: His.Lar.50.AllAg.2nd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.50.AllAg.2nd_instar dm3 Histone Larvae 2nd instar SRX013015,SRX013042,SRX01...3112,SRX013043,SRX013087,SRX013096 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.50.AllAg.2nd_instar.bed ...
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File list: His.Lar.20.AllAg.2nd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available His.Lar.20.AllAg.2nd_instar dm3 Histone Larvae 2nd instar SRX013015,SRX013042,SRX01...3112,SRX013043,SRX013096,SRX013087 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.20.AllAg.2nd_instar.bed ...
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Twentyfourth Podcast - Interview with Lars Holmgaard Christensen
DEFF Research Database (Denmark)
2008-01-01
Every wednesday the Doctoral School of Human Centred Informatics hosts a small research seminar, where PhD students and senior researchers can share and discuss their ongoing work. Today, we bring an interview from spring 2008. On February 27, Lars Holmgaard Christensen presented his paper "Homo...
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File list: ALL.Lar.10.AllAg.1st_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.10.AllAg.1st_instar dm3 All antigens Larvae 1st instar SRX013088,SRX013064,...SRX013044,SRX013009,SRX013072,SRX013097,SRX013055,SRX013056 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.10.AllAg.1st_instar.bed ...
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File list: ALL.Lar.50.AllAg.1st_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.50.AllAg.1st_instar dm3 All antigens Larvae 1st instar SRX013009,SRX013072,...SRX013088,SRX013044,SRX013064,SRX013097,SRX013056,SRX013055 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.50.AllAg.1st_instar.bed ...
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File list: ALL.Lar.20.AllAg.1st_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.20.AllAg.1st_instar dm3 All antigens Larvae 1st instar SRX013009,SRX013072,...SRX013088,SRX013044,SRX013064,SRX013097,SRX013055,SRX013056 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.20.AllAg.1st_instar.bed ...
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File list: ALL.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.05.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX104964,SRX104963,...SRX287718,SRX331401,SRX287658,SRX331366,SRX287906,SRX287678 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.05.AllAg.3rd_instar.bed ...
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File list: ALL.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.10.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX104963,SRX104968,...SRX287718,SRX022334,SRX104976,SRX467107,SRX013086,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.10.AllAg.3rd_instar.bed ...
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File list: ALL.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.20.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX1038029,SRX103803...SRX013082,SRX467107,SRX016173,SRX215499,SRX495243,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.20.AllAg.3rd_instar.bed ...
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File list: ALL.Lar.05.AllAg.1st_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.05.AllAg.1st_instar dm3 All antigens Larvae 1st instar SRX013088,SRX013009,...SRX013064,SRX013044,SRX013072,SRX013055,SRX013097,SRX013056 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.05.AllAg.1st_instar.bed ...
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File list: Unc.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Unc.Lar.50.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038029,SRX103803...1,SRX1038032,SRX1038030,SRX022335,SRX032124,SRX032123,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.50.AllAg.3rd_instar.bed ...
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File list: Oth.Lar.20.Adenine_N6-methylation.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Oth.Lar.20.Adenine_N6-methylation.AllCell ce10 TFs and others Adenine N6-methylatio...n Larvae http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Lar.20.Adenine_N6-methylation.AllCell.bed ...
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File list: Pol.Lar.05.RNA_polymerase_II.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.05.RNA_polymerase_II.AllCell dm3 RNA polymerase RNA polymerase II Larvae SR...SRX151962,SRX182775,SRX661503,SRX013070,SRX013072,SRX013113,SRX013082,SRX151961 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.05.RNA_polymerase_II.AllCell.bed ...
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File list: Pol.Lar.20.RNA_polymerase_II.AllCell [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Pol.Lar.20.RNA_polymerase_II.AllCell dm3 RNA polymerase RNA polymerase II Larvae SR...SRX661503,SRX026742,SRX013070,SRX013072,SRX182775,SRX151961,SRX013082,SRX013113 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.20.RNA_polymerase_II.AllCell.bed ...
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File list: Unc.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Unc.Lar.10.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038029,SRX103803...1,SRX1038032,SRX1038030,SRX032124,SRX032123,SRX022335,SRX022334,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.10.AllAg.3rd_instar.bed ...
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File list: ALL.Lar.05.AllAg.2nd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.05.AllAg.2nd_instar dm3 All antigens Larvae 2nd instar SRX013087,SRX013096,...SRX013043,SRX013015,SRX013112,SRX013042,SRX013113,SRX013016,SRX013114 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.05.AllAg.2nd_instar.bed ...
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File list: ALL.Lar.50.AllAg.2nd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.50.AllAg.2nd_instar dm3 All antigens Larvae 2nd instar SRX013015,SRX013042,...SRX013112,SRX013016,SRX013114,SRX013043,SRX013087,SRX013096,SRX013113 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.50.AllAg.2nd_instar.bed ...
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File list: ALL.Lar.20.AllAg.2nd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ALL.Lar.20.AllAg.2nd_instar dm3 All antigens Larvae 2nd instar SRX013015,SRX013042,...SRX013112,SRX013043,SRX013016,SRX013114,SRX013096,SRX013087,SRX013113 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.20.AllAg.2nd_instar.bed ...
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File list: Unc.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Unc.Lar.20.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038029,SRX103803...1,SRX1038032,SRX1038030,SRX022335,SRX032124,SRX022334,SRX032123,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.20.AllAg.3rd_instar.bed ...
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File list: Unc.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available Unc.Lar.05.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038031,SRX103802...9,SRX1038032,SRX1038030,SRX022335,SRX022334,SRX032124,SRX013058,SRX032123 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.05.AllAg.3rd_instar.bed ...
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Samsun’da Ağır Ceza Mahkemesine Yansıyan Cinsel Suçlar
Directory of Open Access Journals (Sweden)
Berna Aydın
2004-04-01
Full Text Available Çalışmamızda cinsel suçların karakteristik özelliklerini belirlemek ve Türk Ceza Kanunu (TCK’nda yapılan değişiklikler çerçevesinde, cinsel suçlarla ilgili ortaya çıkan farklılıkları değerlendirmek amaçlanmıştır. 1999-2003 yılları arasında Samsun 1. Ağır Ceza Mahkemesi’nde karara bağlanmış dava dosyalarına ait karar kartonları incelenerek, cinsel suçlarla ilgili davalar çalışma kapsamına alınmıştır. Mağdurların %9,4’ü erkek iken, sanıkların tümünün erkek olduğu belirlenmiştir. Sanıkların %43,4’lük oranla en sık 21-30 yaş grubunda, mağdurların ise en sık (%31,6 16-18 yaş grubunda olduğu görülmüştür. Yargıya yansıyan cinsel suçlar arasında en sık ırza geçme suçları olduğu belirlenmiştir. Cinsel suçların adli ve tıbbi boyutu ile ilgilenen tıp ve hukuk mensupları, yeni yasal düzenlemeler yanı sıra cinsel suçların karakteristik özellikleri hakkında da bilgi sahibi olmalıdır. Her ilde ve büyük ilçe merkezlerinde cinsel suçlar değerlendirme merkezleri kurulması gerekmektedir. Anahtar kelimeler: Cinsel suçlar, cinsel saldırı, sanık, mağdur, mahkeme kararı
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Myotonin protein-kinase [AGC]n trinucleotide repeat in seven nonhuman primates
Energy Technology Data Exchange (ETDEWEB)
Novelli, G.; Sineo, L.; Pontieri, E. [Catholic Univ. of Rome (Italy)]|[Univ. of Milan (Italy)]|[Univ. Florence (Italy)] [and others
1994-09-01
Myotonic dystrophy (DM) is due to a genomic instability of a trinucleotide [AGC]n motif, located at the 3{prime} UTR region of a protein-kinase gene (myotonin protein kinase, MT-PK). The [AGC] repeat is meiotically and mitotically unstable, and it is directly related to the manifestations of the disorder. Although a gene dosage effect of the MT-PK has been demonstrated n DM muscle, the mechanism(s) by which the intragenic repeat expansion leads to disease is largely unknown. This non-standard mutational event could reflect an evolutionary mechanism widespread among animal genomes. We have isolated and sequenced the complete 3{prime}UTR region of the MT-PK gene in seven primates (macaque, orangutan, gorilla, chimpanzee, gibbon, owl monkey, saimiri), and examined by comparative sequence nucleotide analysis the [AGC]n intragenic repeat and the surrounding nucleotides. The genomic organization, including the [AGC]n repeat structure, was conserved in all examined species, excluding the gibbon (Hylobates agilis), in which the [AGC]n upstream sequence (GGAA) is replaced by a GA dinucleotide. The number of [AGC]n in the examined species ranged between 7 (gorilla) and 13 repeats (owl monkeys), with a polymorphism informative content (PIC) similar to that observed in humans. These results indicate that the 3{prime}UTR [AGC] repeat within the MT-PK gene is evolutionarily conserved, supporting that this region has important regulatory functions.
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Finding Neutrinos in LArTPCs using Convolutional Neural Networks
Wongjirad, Taritree
2017-09-01
Deep learning algorithms, which have emerged over the last decade, are opening up new ways to analyze data for many particle physics experiments. MicroBooNE, which is a neutrino experiment at Fermilab, has been exploring the use of such algorithms, in particular, convolutional neural networks (CNNS). CNNs are the state-of-the-art method for a large class of problems involving the analysis of images. This makes CNNs an attractive approach for MicroBooNE, whose detector, a liquid argon time projection chamber (LArTPC), produces high-resolution images of particle interactions. In this talk, I will discuss the ways CNNs can be applied to tasks like neutrino interaction detection and particle identification in MicroBooNE and LArTPCs.
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Brinquedo e educação: na escola e no lar
Directory of Open Access Journals (Sweden)
Edda Bomtempo
Full Text Available Como o artigo mostra, brinquedo, brincar e jogar são considerados de grande importância para o desenvolvimento humano. Os tópicos considerados são: aprender brincando ou brincar para aprender; papéis educacionais dos brinquedos e jogos; os professores e os brinquedos; brinquedos e jogos no lar e na escola; o lar como um lugar divertido. Pais e professores precisam estar informados do valor dos brinquedos, brincadeiras e jogos para o desenvolvimento das crianças e dos adolescentes.
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Kui lokaalne saab olla, et jääda globaalselt huvitavaks? / Lars Nittve ; interv. Anna Mustonen
Nittve, Lars
2005-01-01
Stockholmi moodsa kunsti muuseumi Moderna Museeti direktor Lars Nittve räägib kaasaegse kunstimuuseumi kogumispoliitika väljakutsetest ja rahvuslikkuse aspektist. Lars Nittve eluloolisi andmeid, lühidalt Moderna Museet'ist
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Distonia laríngea respiratória
Directory of Open Access Journals (Sweden)
Lebl Mariana Dantas Aumond
2003-01-01
Full Text Available A distonia laríngea respiratória (DLR é uma desordem rara caracterizada por espasmos da musculatura adutora das pregas vocais durante a fase inalatória da respiração, com manifestação clínica de dispnéia e estridor. O diagnóstico etiológico do estridor laríngeo, entretanto, nem sempre é fácil de ser realizado, principalmente em situações emergenciais, de forma que a DLR pode não ser diagnosticada, o que nos leva a supor ser mais freqüente do que usualmente é descrita. O diagnóstico da DRL requer primeiramente a realização de uma história médica e exames laringológico e neurológico apropriados, com ênfase na verificação da presença de características distônicas e na exclusão de outras etiologias causadoras de movimentos paradoxais de pregas vocais. Muitos tratamentos foram propostos para a DLR, mas nenhum deles apresentou resultados satisfatórios. O uso da Toxina Botulínica do tipo A (Botox® no músculo tireoaritenoídeo tem oferecido melhoras admiráveis, apesar dos poucos casos descritos. Apresentamos dois casos clínicos de pacientes com DLR tratados com Botox® que apresentavam o fechamento glótico inspiratório causado tanto pelos espasmos anômalos dos músculos tireoaritenoídeos, como pela movimentação paradoxal da epiglote. Dentro da classificação proposta por Koufman e Blabock para as distonias laríngeas, inserimos um novo subtipo de DLR caracterizado pela presença de paroxismos de adução de estruturas glóticas e supraglóticas durante a respiração.
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File list: InP.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.50.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX287726,SRX331369...87917,SRX287921,SRX288023,SRX467107,SRX016172,SRX016173 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.50.AllAg.3rd_instar.bed ...
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GÜREL, Ramazan
2014-01-01
Bu makale, Bandura'nın 5-11 yaş aralığındaki çocukların ahlaki yargılarının şekillenmesinde model alma ve sosyal pekiştireçlerin etkisini test etmek üzere gerçekleştirdiği araştırmasının ulaştığı sonuçları değerlendirmeyi amaçlamaktadır. Bu doğrultuda makalede, Bandura tarafından üç farklı deney ortamında 5-11 yaşlarındaki çocuklar üzerinde, ahlaki gelişim ve uyum sağlamada sosyal öğrenme, pekiştireçler ve model davranışlarının etkilerine dair gerçekleştirilen deneysel faaliyetlerin uygu...
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Ω-deformed SYM on a Gibbons-Hawking space
International Nuclear Information System (INIS)
Dey, Anindya
2015-01-01
We study an N=2, pure U(1) SYM theory on a Gibbons-Hawking space Ω-deformed using the U(1) isometry. The resultant 3D theory, after an appropriate “Nekrasov-Witten" change of variables, is asymptotically equivalent to the undeformed theory at spatial infinity but differs from it as one approaches the NUT centers which are fixed points under the U(1) action. The 3D theory may be recast in the form of a generalized hyperkähler sigma model introduced in http://dx.doi.org/10.1007/JHEP04(2014)158 where the target space is a one-parameter family of hyperkähler spaces. The hyperkähler fibers have a preferred complex structure which for the deformed theory depends on the parameter of Ω-deformation. The metric on the hyperkähler fiber can be reduced to a standard metric on ℂ×T 2 with the modular parameter of the torus depending explicitly on the Ω-deformation parameter. The contribution of the NUT center to the sigma model path integral, expected to be a holomorphic section of a holomorphic line bundle over the target space on grounds of supersymmetry, turns out to be a Jacobi theta function in terms of certain “deformed" variables.
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Memecik Zeytinyağlarının Biyokimyasal Karakterizasyonu
Directory of Open Access Journals (Sweden)
Huri İlyasoğlu
2015-02-01
Full Text Available Zeytinyağı kalitesi botanik ve coğrafi orijin ile ilişkili olduğundan zeytinyağının çeşit ve bölgesel karakterizasyonu önem kazanmıştır. Bu çalışmada, ülkemizin ekonomik açıdan en önemli zeytinyağlarından birisi olan Memecik zeytinyağlarının kalite parametreleri, yağ asitleri, triaçilgliserol ve sterol kompozisyonu, a-tokoferol ve toplam fenolik madde içerikleri, fenolik madde ve aroma profili belirlenmiştir. Analiz edilen zeytinyağı örneklerinin kalite parametreleri, yağ asitleri ve sterol kompozisyonun (kampesterol hariç, Türk Gıda Kodeksi ile uyumlu olduğu saptanmıştır. Memecik zeytinyağlarında tespit edilen başlıca yağ asitleri oleik asit (% 73.37-75.64, palmitik asit (% 11.45-13.84 ve linoleik asittir (% 7.33-8.91. Triolein (% 63.50-68.32, palmitodiolein (% 18.25-25.82 ve dioleolinolein (% 6.01-9.18 zeytinyağı örneklerinde tespit edilen başlıca triaçilgliserollerdir. Sterol kompozisyonu oluşturan başlıca steroller, b-sitosterol (% 80.76-83.00, D5-avenasterol (% 11.02-12.78 ve kampesteroldür (% 4.01-4.97. Memecik çeşidi zeytinyağlarının fenolik madde profilinde, hidroksitirozol, tirozol, ferulik asit, p-kumarik asit, apigenin ve luteolin ve aroma profilinde hekzanal, hekzanol, E-2-hekzenal, E-2-hekzenol ve Z-3-hekzenol tespit edilmiştir.
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File list: InP.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.20.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX467108,SRX287726...67103,SRX288024,SRX288023,SRX104976,SRX016172,SRX467107,SRX016173 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.20.AllAg.3rd_instar.bed ...
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File list: InP.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.10.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX016172,SRX016173...87701,SRX287922,SRX467104,SRX287918,SRX287718,SRX104976,SRX467107 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.10.AllAg.3rd_instar.bed ...
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File list: InP.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available InP.Lar.05.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX016173,SRX288024...87921,SRX287718,SRX331401,SRX287658,SRX331366,SRX287906,SRX287678 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.05.AllAg.3rd_instar.bed ...
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Halkın Genetiği Değiştirilmiş Ürünlere/Üretilme Süreçlerine Yönelik Algıları ve Etik İnançları
Directory of Open Access Journals (Sweden)
Özlen Özgen
2014-02-01
Full Text Available Bu araştırmanın amacı, halkın genetiği değiştirilmiş ürünlere ve üretilme süreçlerine yönelik fayda/risk algıları ile etik inançları arasındaki ilişkinin incelenmesidir. Araştırma materyalinin toplanmasında karşılıklı görüşme tekniği kullanılmıştır. Likert tipi cümlelere verilen yanıtlar puanlanmış, geçerlik ve güvenirlik analizi yapılmıştır. Yaş değişkenine bağlı farklılığın belirlenebilmesi için t-testi uygulanmıştır. Bireylerin genetiği değiştirilmiş ürünlere/üretilme süreçlerine bağlı fayda/risk algıları ile etik inançları arasındaki ilişkinin incelenmesi amacı ile Pearson korelasyon analizi yapılmıştır. Bulgular; tüketicilerin genetiği değiştirilmiş ürünlere ilişkin fayda algılarının, genetiği değiştirilmiş ürünlere ve üretilme süreçlerine ilişkin risk algılarının, genetiği değiştirilmiş ürünlere ve üretilme süreçlerine ilişkin etik inançlarının yaşa bağlı olarak değiştiğini göstermektedir. Pearson korelasyon analizi sonucunda p<0.001 düzeyinde anlamlı ilişkiler saptanmıştır.
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Developing Light Collection Enhancements and Wire Tensioning Methods for LArTPC Neutrino Detectors
Energy Technology Data Exchange (ETDEWEB)
Spagliardi, Fabio [Univ. of Manchester (United Kingdom)
2017-01-01
Liquid argon Time Projection Chambers (LArTPCs) are becoming widely used as neutrino detectors because of their image-like event reconstruction which enables precision neutrino measurements. They primarily use ionisation charge to reconstruct neutrino events. It has been shown, however, that the scintillation light emitted by liquid argon could be exploited to improve their performance. As the neutrino measurements planned in the near future require large-scale experiments, their construction presents challenges in terms of both charge and light collection. In this dissertation we present solutions developed to improve the performance in both aspects of these detectors. We present a new wire tensioning measurement method that allows a remote measurement of the tension of the large number wires that constitute the TPC anode. We also discuss the development and installation of WLS-compound covered foils for the SBND neutrino detector at Fermilab, which is a technique proposed t o augment light collection in LArTPCs. This included preparing a SBND-like mesh cathode and testing it in the Run III of LArIAT, a test beam detector also located at Fermilab. Finally, we present a study aimed at understanding late scintillation light emitted by recombining positive argon ions using LArIAT data, which could affect large scale surface detectors.
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Dead Time in the LAr Calorimeter Front-End Readout
Gingrich, D M
2002-01-01
We present readout time, latency, buffering, and dead-time calculations for the switched capacitor array controllers of the LAr calorimeter. The dead time is compared with algorithms for the dead-time generation in the level-1 central trigger processor.
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Genetic association analysis of LARS2 with type 2 diabetes
DEFF Research Database (Denmark)
Reiling, E; Jafar-Mohammadi, B; van 't Riet, E
2010-01-01
was to establish the true contribution of this variant and common variants in LARS2 (MAF > 5%) to type 2 diabetes risk. METHODS: We combined genome-wide association data (n = 10,128) from the DIAGRAM consortium with independent data derived from a tagging single nucleotide polymorphism (SNP) approach in Dutch...... individuals (n = 999) and took forward two SNPs of interest to replication in up to 11,163 Dutch participants (rs17637703 and rs952621). In addition, because inspection of genome-wide association study data identified a cluster of low-frequency variants with evidence of type 2 diabetes association, we...... of sequence variants in LARS2 in type 2 diabetes susceptibility, we found no evidence to support previous data indicating a role in type 2 diabetes susceptibility....
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Arrival of the last cryostat for the ATLAS LAr calorimeter at CERN
Aleksa, M; Oberlack, H
On Wednesday, 4th June the last cryostat for the ATLAS LAr calorimeter (end-cap A) arrived at CERN and was immediately unloaded from the truck in building 180 (see Figures 1 and 2), where the integration of the LAr calorimeters into their cryostats takes place. The transport from the Italian company SIMIC, where both end-cap calorimeters have been produced took longer than expected due to delays because of the G8 summit. Thanks to the great effort by the CERN Host State office and the French-German steering group that supplies the end-cap cryostat as an in-kind contribution to the LAr collaboration, an exceptional convoy was finally available and the cryostat could make its way to CERN. Fig.1 (left): Truck with the end-cap cryostat. Fig.2 (right): Unloading the cryostat in bldg. 180. Each end-cap cryostat will contain an electromagnetic calorimeter wheel, two wheels of a hadronic calorimeter, and a forward calorimeter. The design of the cryostat as a double vessel structure made of Aluminum fulfills t...
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ATLAS LAr Calorimeter Performance in LHC Run-2
Morgenstern, Stefanie; The ATLAS collaboration
2018-01-01
Liquid-argon (LAr) sampling calorimeters are employed by ATLAS for all electromagnetic calorimetry in the pseudo-rapidity region $\\eta<3.2$, and for hadronic and forward calorimetry in the region from $\\eta=1.5$ to $\\eta=4.9$. In the first LHC run a total luminosity of $27\\,\\mathrm{fb}^{-1}$ has been collected at centre-of-mass energies of $7-8\\,\\mathrm{TeV}$. After detector consolidation during a long shutdown, Run-2 started in 2015 and $86.4\\,\\mathrm{fb}^{-1}$ of data at a centre-of-mass energy of $13\\,\\mathrm{TeV}$ have been recorded. In order to realize the level-1 acceptance rate of $100\\,\\mathrm{kHz}$ in Run-2 data taking, the number of readout samples recorded and used for the energy and the time measurement has been modified from five to four while keeping the expected performance. The well calibrated and highly granular LAr calorimeter reached its design values both in energy measurement as well as in direction resolution. This contribution will give an overview of the detector operation, hardware...
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Mobil reklamlar ve mobil reklam araçlarına yönelik tutumlar
Barutçu, Süleyman; Öztürk Göl, Meltem
2009-01-01
Bu çalışmanın amacı, pazarlama bölümü yöneticilerinin dikkatlerini mobil iletişim teknolojilerindeki gelişmelerin sonucu olarak ortaya çıkan mobil pazarlama ve mobil reklam uygulamalarına çekmektir. Çalışmanın kavramsal analiz bölümünde mobil pazarlama, mobil reklamların önemi açıklanmış ve mobil reklam araçları (SMS, MMS ve Bluetooth Reklamları) analiz edilmiştir. Araştırma bölümünde ise mobil telefon kullanıcılarının mobil reklam araçlarına yönelik tutumlarının karşılaştırmalı olarak belirl...
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Budget impact of pasireotide LAR for the treatment of acromegaly, a rare endocrine disorder.
Zhang, J J; Nellesen, D; Ludlam, W H; Neary, M P
2016-01-01
Acromegaly is a rare disorder characterized by the over-production of growth hormone (GH). Patients often experience a range of chronic comorbidities including hypertension, cardiac dysfunction, diabetes, osteoarthropathy, and obstructive sleep apnea. Untreated or inadequately controlled patients incur substantial healthcare costs, while normalization of GH levels may reduce morbidity and mortality rates to be comparable to the general population. To assess the 3-year budget impact of pasireotide LAR on a US managed care health plan following pasireotide LAR availability. Two separate economic models were developed: one from the perspective of an entire health plan and another from the perspective of a pharmacy budget. The total budget impact model includes costs of drug therapies and other costs for treatment, monitoring, management of adverse events, and comorbidities. The pharmacy cost calculator only considers drug costs. The total estimated budget impact associated with the introduction of pasireotide LAR is 0.31 cents ($0.0031) per member per month (PMPM) in the first year, 0.78 cents ($0.0078) in the second year, and 1.42 cents ($0.0142) in the third year following FDA approval. Costs were similar or lower from a pharmacy budget impact perspective. For each patient achieving disease control, cost savings from reduced comorbidities amounted to $10,240 per year. Published data on comorbidities for acromegaly are limited. In the absence of data on acromegaly-related costs for some comorbidities, comorbidity costs for the general population were used (may be under-estimates). The budget impact of pasireotide LAR is expected to be modest, with an expected increase of 1.42 cents PMPM on the total health plan budget in the third year after FDA approval. The efficacy of pasireotide LAR in acromegaly, as demonstrated in head-to-head trials compared with currently available treatment options, is expected to be associated with a reduction of the prevalence of
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DEFF Research Database (Denmark)
Pedersen, Lene; Johann, Stephen V; van Zeijl, Marja
1995-01-01
Glvr1 encodes the human receptor for gibbon ape leukemia virus (GALV) and feline leukemia virus subgroup B (FeLV-B), while the related gene Glvr2 encodes the human receptor for amphotropic murine leukemia viruses (A-MLVs). The two proteins are 62% identical in their amino acid sequences...
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Baleanu, Dumitru; Inc, Mustafa; Yusuf, Abdullahi; Aliyu, Aliyu Isa
2018-06-01
In this work, we investigate the Lie symmetry analysis, exact solutions and conservation laws (Cls) to the time fractional Caudrey-Dodd-Gibbon-Sawada-Kotera (CDGDK) equation with Riemann-Liouville (RL) derivative. The time fractional CDGDK is reduced to nonlinear ordinary differential equation (ODE) of fractional order. New exact traveling wave solutions for the time fractional CDGDK are obtained by fractional sub-equation method. In the reduced equation, the derivative is in Erdelyi-Kober (EK) sense. Ibragimov's nonlocal conservation method is applied to construct Cls for time fractional CDGDK.
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ATLAS LAr Calorimeter Performance in LHC Run-2
Morgenstern, Stefanie; The ATLAS collaboration
2018-01-01
Liquid argon (LAr) sampling calorimeters are employed by ATLAS for all electromagnetic calorimetry in the pseudo-rapidity region eta<3.2, and for hadronic and forward calorimetry in the region from eta=1.5 to eta=4.9. In the first LHC run a total luminosity of 27 fb-1 has been collected at c.o.m energies of 7-8 TeV. After detector consolidation during a long shutdown, Run-2 started in 2015 and 86.4fb-1 of data at a c.o.m energy of 13 TeV have been recorded. In order to realize the level-1 acceptance rate of 100 kHz in Run-2 data taking, the number of read-out samples recorded and used for the energy and the time measurement has been modified from five to four while keeping the expected performance. The well calibrated and highly granular LAr Calorimeter reached its design values both in energy measurement as well as in direction resolution. This contribution will give an overview of the detector operation, hardware improvements, changes in the monitoring and data quality procedures, to cope with increased ...
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LAr calorimeter for SCC with a common vacuum bulkhead---a concept to improve hermeticity
International Nuclear Information System (INIS)
Pope, W.L.; Watt, R.D.
1989-11-01
A new concept for a Barrel/Endcap LAr Calorimeter (LAC) is described in which the Barrel and Endcaps are in separate vacuum enclosures but share a common vacuum bulkhead (CVB). We explore 2 possible bulkhead construction types; welded plate sandwich panels, and brazed sandwich panels in which the core is an isotropic cellular solid--foamed aluminum. Gas lines and electric cables from he innermost Drift Chamber pass through radial holes in the core of the sandwich bulkhead. The CVB concept offers the potential to obtain a more hermetic calorimeter with significantly reduced dead material and/or space in the interface region common to conventional design LAr detectors for the SSC with Endcap features. To utilize a common additional steps to remove the Drift Chamber, a large increase in Endcap standby heat leak, and perhaps, new cryogenic safety issues. We find that significant amount of dead mass can be removed from critical regions of the vacuum shells when compared to a promising SSC LAC reference design. It is also shown that the increased standby heat leak of this concept can be easily removed by existing cooling capacity in another large LAr calorimeter. It is further shown that shut-downs need not be appreciably longer. Finally, it is argued that cryogen spill hazards can be avoided if the Endcap's LAr is removed during Drift chamber maintenance shutdowns, and that cryogenic safety is not compromised
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Borah, Mrigakhi; Devi, Ashalata; Kumar, Awadhesh
2018-01-01
Forest fragmentation alters plant species diversity and composition, and causes diverse affects on the feeding behavior of wild primates. We investigated the feeding behavior and diet of two groups of western hoolock gibbon (Hoolock hoolock) inhabiting a small isolated forest patch (21 km 2 ) in Hollongapar Gibbon Wildlife Sanctuary, Assam, Northeast India, over a year using focal animal sampling. H. hoolock adults spent, on average, 35.2% of their total annual activity budget on feeding, and fed on young leaves, mature leaves, flowers, fruits, petioles, buds and also on animal matter. There was marked seasonal variation in the proportions of the dietary items consumed. Fruits accounted for an average of 51% (range 34-71% per month) of feeding time over the year. This highly frugivorous diet may limit the ability of the species to survive in small and disturbed forest fragments. A total of 54 plant species (32 families) were consumed by the focal groups during the study period, but there were variations between months in the selection of these plant species. Non-tree species such as lianas were among the most highly selected species in the diet. Moraceae, comprising ten species, was the most dominant family among the food plants, accounting for 36% of annual feeding time. The present study presents quantitative and qualitative data on dietary composition, preference and selection of food plants of H. hoolock in a fragmented habitat, which can contribute to the restoration and manipulation of degraded habitats of H. hoolock.
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Operation plan for the data 100/LARS terminal system
Bowen, A. J., Jr.
1980-01-01
The Data 100/LARS terminal system provides an interface for processing on the IBM 3031 computer system at Purdue University's Laboratory for Applications of Remote Sensing. The environment in which the system is operated and supported is discussed. The general support responsibilities, procedural mechanisms, and training established for the benefit of the system users are defined.
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Readout Electronics for the ATLAS LAr Calorimeter at HL-LHC
Chen, H; The ATLAS collaboration
2011-01-01
The ATLAS experiment is one of the two general-purpose detectors designed to study proton-proton collisions (14 TeV in the center of mass) produced at the Large Hadron Collider (LHC) and to explore the full physics potential of the LHC machine at CERN. The ATLAS Liquid Argon (LAr) calorimeters are high precision, high sensitivity and high granularity detectors designed to provide precision measurements of electrons, photons, jets and missing transverse energy. ATLAS (and its LAr Calorimeters) has been operating and collecting p-p collisions at LHC since 2009. The on-detector electronics (front-end) part of the current readout electronics of the calorimeters measures the ionization current signals by means of preamplifiers, shapers and digitizers and then transfers the data to the off-detector electronics (back-end) for further elaboration, via optical links. Only the data selected by the level-1 calorimeter trigger system are transferred, achieving a bandwidth reduction to 1.6 Gbps. The analog trigger sum sig...
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Altın Fiyatlarının Yapay Sinir Ağları ile Tahmini ve Bir Uygulama
Directory of Open Access Journals (Sweden)
Rıdvan YÜKSEL
2016-03-01
Full Text Available Bu çalışmada altın fiyatlarını yapay sinir ağları ile öngörmek amacıyla, altın fiyatlarını etkileyebileceği düşünülen değişkenler olan Gümüş fiyatları, Brent Petrol fiyatları, ABD doları/ EUR paritesi, EuroNext100 endeksi, Amerika Dow Jones Endeksi, 13 Hafta vadeli ABD bonosu faiz oranı ve ABD TÜFE endeksi kullanılarak modeller kurulmuştur. Yapay sinir ağları ile kurulan modellerden elde edilen tahmin sonuçları, gerçek değerler ile R2, RMSE, MAE ve MAPE (% gibi performans kriterleri hesaplanarak karşılaştırılmıştır. Elde edilen bulgular yapay sinir ağlarının altın fiyatlarının tahmininde başarı ile kullanılabileceğini göstermektedir. Yapılan duyarlılık analizinin sonuçları değerlendirildiğinde altın fiyatlarını etkileyen faktörlerin başında gümüş ve petrol fiyatlarının geldiği tespit edilmiştir.
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Genetic association analysis of LARS2 with type 2 diabetes
E. Reiling (Erwin); B. Jafar-Mohammadi (Bahram); E. van 't Riet (Esther); M.N. Weedon (Michael); J.V. van Vliet-Ostaptchouk (Jana); T. Hansen (Torben); R. Saxena (Richa); T.W. van Haeften (Timon); P.P. Arp (Pascal); S. Das; M.G.A.A.M. Nijpels (Giel); M.J. Groenewoud (Marlous); E.C. van Hove (Els); A.G. Uitterlinden (André); J.W.A. Smit (Jan); A.D. Morris (Andrew); A.S.F. Doney (Alex); C.N.A. Palmer (Colin); C. Guiducci (Candace); A.T. Hattersley (Andrew); T.M. Frayling (Timothy); O. Pedersen (Oluf); P.E. Slagboom (Eline); D. Altshuler (David); L. Groop (Leif); J.A. Romijn; J.A. Maassen (Johannes); M.A. Hofker (Marten); J.M. Dekker (Jacqueline); M.I. McCarthy (Mark); L.M. 't Hart (Leen)
2010-01-01
textabstractAims/hypothesis: LARS2 has been previously identified as a potential type 2 diabetes susceptibility gene through the low-frequency H324Q (rs71645922) variant (minor allele frequency [MAF] 3.0%). However, this association did not achieve genome-wide levels of significance. The aim of this
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Brüssel Euroopa pealinnaks? / Ülar Mark
Mark, Ülar, 1968-
2009-01-01
Brüsseli Euroopa kvartali planeerimisvõistlusest, mille peakorraldaja oli Brüsseli pealinna piirkond koos Brüsseli linna ja Euroopa Komisjoniga. Eestist osales žüriis arhitekt Ülar Mark. Meeskonna Atelier Christian de Portzamparc võidutööst ja teiste teise vooru pääsenud nelja meeskonna (JDS / Julien De Smedt Architects, OMA / Office for Metropolitan Architecture, Xaveer De Geyter Architect, Fletcher Priest Architects) töödest
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Application of SDSM and LARS-WG for simulating and downscaling of rainfall and temperature
Hassan, Zulkarnain; Shamsudin, Supiah; Harun, Sobri
2014-04-01
Climate change is believed to have significant impacts on the water basin and region, such as in a runoff and hydrological system. However, impact studies on the water basin and region are difficult, since general circulation models (GCMs), which are widely used to simulate future climate scenarios, do not provide reliable hours of daily series rainfall and temperature for hydrological modeling. There is a technique named as "downscaling techniques", which can derive reliable hour of daily series rainfall and temperature due to climate scenarios from the GCMs output. In this study, statistical downscaling models are used to generate the possible future values of local meteorological variables such as rainfall and temperature in the selected stations in Peninsular of Malaysia. The models are: (1) statistical downscaling model (SDSM) that utilized the regression models and stochastic weather generators and (2) Long Ashton research station weather generator (LARS-WG) that only utilized the stochastic weather generators. The LARS-WG and SDSM models obviously are feasible methods to be used as tools in quantifying effects of climate change condition in a local scale. SDSM yields a better performance compared to LARS-WG, except SDSM is slightly underestimated for the wet and dry spell lengths. Although both models do not provide identical results, the time series generated by both methods indicate a general increasing trend in the mean daily temperature values. Meanwhile, the trend of the daily rainfall is not similar to each other, with SDSM giving a relatively higher change of annual rainfall compared to LARS-WG.
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Peynirlere Kontamine Olan Küflerin Bazı Esansiyel Yağlar ile İnhibisyonu
Directory of Open Access Journals (Sweden)
Sibel Özçakmak
2015-02-01
Full Text Available Küf kontaminasyonu önemli kalite problemlerine ve peynir üreticilerine ekonomik kayıplara neden olmaktadır. Peynirlerden yaygın olarak izole edilen kontamine küf türleri Penicillium commune, P. verrucosum, P. roqueforti, P. palitans, Aspergillus flavus ve Geotrichum candidum olarak belirlenmiştir. Sorbik asit veya bunların tuzları, bozulma etmeni küflerin önlenmesi için peynir yüzeylerine uygulanmaktadır. Bazı sentetik gıda katkılarının kullanımıyla ilgili gıda endüstrisi ve mevzuatı oluşturan kuruluşlar tarafından getirilen kısıtlamalar doğal antimikrobiyel bileşikler üzerine araştırmaların doğmasına neden olmuştur. Bitki ve baharat, gıdaların mikrobiyolojik güvenliğini sağlayan etkili bileşiklere sahiptir. Salvia officinalis (ada çayı, Laurus nobilis (defne, Cinnamomum zeylanicum (tarçın, Thymus vulgaris (kekik, Cymbopogon citratus (limon otu, Origanum vulgare (keklik otu esansiyel yağları, bozulma etmeni küf şorasını inhibe edebilmiştir. Thymol ve karanfil esansiyel yağlarının Çedar peynirinde P. citrinum, Kaşar peynirinde A. flavus; zeytin yaprağı ekstraklarının, Tulum peynirinde A. niger, P. citrinum ve P. roqueforti, beyaz peynirde Mucor rocemosus’un gelişimini inhibe edebildiği bildirilmiştir.
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ATLAS LAr Calorimeter Performance and Commissioning for LHC Run-2
Spettel, Fabian; The ATLAS collaboration
2015-01-01
The ATLAS detector was designed and built to study proton-proton colli- sions produced at the LHC at centre-of-mass energies up to 14 TeV and in- stantaneous luminosities up to $10^{34} \\text{cm}^{-2} \\text{s}^{-1}$. Liquid argon (LAr) sampling calorimeters are employed for all electromagnetic calorimetry in the pseudorapidity region $|\\eta|<3.2$, and for hadronic calorimetry in the region from $|\\eta|=1.5$ to $|\\eta|=4.9$. In the first LHC run a total luminosity of 27 $\\text{fb}^{-1}$ as been collected at center-of-mass energies of 7-8 TeV with very high operational efficiency of the LAr Calorimeters and excellent performance. The well calibrated and highly granular detector achieved its design values both in energy measurement as well as in direction resolution, which was a main ingredient for the successul discovery of a Higgs boson in the di-photon decay channel. The talk will give an overview of the procedures applied to calibrate the 180.000 read-out channels electronically as well as from using refe...
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The WA105-3x1x1 m3 dual phase LAr-TPC demonstrator
Murphy, Sebastien
2016-11-15
The dual phase Liquid Argon Time Projection Chamber (LAr TPC) is the state-of-art technology for neutrino detection thanks to its superb 3D tracking and calorimetry performance. Its main feature is the charge amplification in gas argon which provides excellent signal-to-noise ratio. Electrons produced in the liquid argon are extracted in the gas phase. Here, a readout plane based on Large Electron Multiplier detectors provides amplification of the charges before its collection onto an anode with strip readout. The charge amplification enables constructing fully homoge- nous giant LAr-TPCs with tuneable gain, excellent charge imaging performance and increased sensitivity to low energy events. Following a staged approach the WA105 collaboration is con- structing a dual phase LAr-TPC with an active volume of 3x1x1m3 that will soon be tested with cosmic rays. Its construction and operation aims to test scalable solutions for the crucial aspects of this technology: ultra high argon purity in non-evacuable tank, la...
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Aladağlar da Bitki Formasyonları ve Dağılışları
ÜNALDI, Ülkü ESER; TOROĞLU, Emin
2007-01-01
Bulunduğu konum itibariyle Türkiye\\'de yetişme şartlarının bitki gelişimine ve çeşitliliğine uygun koşullar taşıdığı yerlerden biri de Aladağlar\\'dır. Nitekim dağda orman, çalı ve ot formasyonları yer almaktadır. Orman formasyonu kuru ormanlar ve yarı nemli ormanlar olmak üzere ikiye ayrılmaktadır. Kuru ormanlar güney yamaçta 250-1300mler, kuzey yamaçta 1400–2400 mler arasında uzanmaktadır. Kuru ormanların hakim elemanları güney yamaçlarda kızılçam, kuzey yamaçlarda i...
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Nõmme maja "Kergus" : Kerese tn., Tallinn / Ülar Mark, Kalle Komissarov
Mark, Ülar
1999-01-01
Kahekorruselise, tänavapoolse pika umbse seinaga eramu projekteeris Arhitektuuribüroo Mark & Tamm, arhitekt Ülar Mark, kaasautor Kalle Komissarov. Konstruktiivne osa: Randväli & Karema Inseneribüroo. Projekt 1997, hoone valmis 1999. Eramu tähenduse ümbermõtestamisest. 13 illustratsiooni: korruste plaanid, välisvaated, sisevaade.Mark & Tamm (arhitektibüroo)
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Electron Attenuation Measurement using Cosmic Ray Muons at the MicroBooNE LArTPC
Energy Technology Data Exchange (ETDEWEB)
Meddage, Varuna [Kansas State U., Manhattan
2017-10-01
The MicroBooNE experiment at Fermilab uses liquid argon time projection chamber (LArTPC) technology to study neutrino interactions in argon. A fundamental requirement for LArTPCs is to achieve and maintain a low level of electronegative contaminants in the liquid to minimize the capture of drifting ionization electrons. The attenuation time for the drifting electrons should be long compared to the maximum drift time, so that the signals from particle tracks that generate ionization electrons with long drift paths can be detected efficiently. In this talk we present MicroBooNE measurement of electron attenuation using cosmic ray muons. The result yields a minimum electron 1/e lifetime of 18 ms under typical operating conditions, which is long compared to the maximum drift time of 2.3 ms.
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Histogramming in the LATOME-firmware for the Phase-1 upgrade of the ATLAS LAr calorimeter readout
Energy Technology Data Exchange (ETDEWEB)
Horn, Philipp; Hentges, Rainer; Straessner, Arno [Institut fuer Kern- und Teilchenphysik, Dresden (Germany)
2016-07-01
Due to the increased luminosity and the higher effective event rate after the phase 1 upgrade the ATLAS LAr detector needs new trigger electronics. The so-called LATOME-Board was designed as a LAr Digital Processing Blade (LPDB) to reconstruct the energy deposited by the particles and is an important part of the read out system. A prototype has already been build and the firmware for the on-board FPGA is under development. The insertion of a histogram-builder in this device gives the unique opportunity to look at untriggered data. This talk provides an insight in the LATOME-firmware and shows the different possibilities to implement the histogram-builder.
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HALICI, Mehmet Gökhan; AKSOY, Ahmet
2014-01-01
Three hundred and two lichenised fungi taxa belonging to 90 genera and 45 lichenicolous fungi taxa belonging to 24 genera are reported from Aladağlar National Park. Of these, 290 lichenised fungi taxa and 21 lichenicolous fungi taxa are reported for the first time from Aladağlar National Park. Nine species of lichenised fungi, namely Arthopyrenia fraxini A.Massal., Aspicilia obscurata (Fr.) Arnold, Cephalophysis leucospila (Anzi) H.Kilias & Scheid., Chaenotheca ferruginea (Turner ex S...
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Directory of Open Access Journals (Sweden)
Masanori Nakata
2016-01-01
Full Text Available Pituitary adenylate cyclase-activating polypeptide (PACAP acts on multiple processes of glucose and energy metabolism. PACAP potentiates insulin action in adipocytes and insulin release from pancreatic β-cells, thereby enhancing glucose tolerance. Contrary to these effects at organ levels, PACAP null mice exhibit hypersensitivity to insulin. However, this apparent discrepancy remains to be solved. We aimed to clarify the mechanism underlying the antidiabetic phenotype of PACAP null mice. Feeding with high-fat diet (HFD impaired insulin sensitivity and glucose tolerance in wild type mice, whereas these changes were prevented in PACAP null mice. HFD also impaired insulin-induced Akt phosphorylation in the liver in wild type mice, but not in PACAP null mice. Using GeneFishing method, HFD increased the leukocyte common antigen-related (LAR protein tyrosine phosphatase in the liver in wild type mice. Silencing of LAR restored the insulin signaling in the liver of HFD mice. Moreover, the increased LAR expression by HFD was prevented in PACAP null mice. HFD increased the expression of VPAC1 receptor (VPAC1-R, one of three PACAP receptors, in the liver of wild type mice. These data indicate that PACAP-VPAC1-R signaling induces LAR expression and insulin resistance in the liver of HFD mice. Antagonism of VPAC1-R may prevent progression of HFD-induced insulin resistance in the liver, providing a novel antidiabetic strategy.
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Directory of Open Access Journals (Sweden)
Naccache Deeb
2011-08-01
Full Text Available Abstract Introduction The safety of octreotide use, in its short-acting preparation, in pregnancy is still unclear. This report provides the first documentation of uneventful octreotide LAR use during three pregnancies in a woman with bronchial carcinoid-associated adrenocorticotropic hormone-dependent Cushing's syndrome. Case presentation A 25-year-old Arabic woman presented to our emergency department with rapid onset of headache, flaring acne and hirsutism, facial puffiness, weight gain and paroxysmal myopathy, and paranoiac thoughts of rape and sexual intimidation. After undergoing surgical removal of a mass by left lower lung lobectomy, her residual lung disease medical therapy failed. Chronic octreotide LAR injections were initiated as indicated by a positive octreoscan. Follow-up revealed a long-lasting positive response to octreotide. Avidity of octreotide to somatostatin receptor sub-type 2 was later confirmed by a positive somatostatin receptor sub-type 2 in the resected tumor specimen. Against our instructions, the patient had three spontaneous pregnancies leading to delivery of three full-term healthy children while her octreotide LAR therapy continued. Conclusion This case adds more data supporting the potential for the safe use of octreotide and the feasibility of octreotide LAR use during pregnancy, making compliance with the patient's preference not to withdraw octreotide therapy as soon as her pregnancy is confirmed a thoughtful option.
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A CULPA É DA MULHER: O Anticristo, de Lars von Trier
Directory of Open Access Journals (Sweden)
João Nunes Silva
2016-08-01
Full Text Available RESUMO O Anticristo, filme de Lars von Trier, lançado em 2009, mostra o desespero de um casal ao perder seu único filho. Extremamente polêmico e repleto de referências bíblicas - a começar pelo título -, é um filme que choca pelo incessante desespero de uma mãe em luto que parece carregar o peso do mundo em sua condição de mulher. A proposta deste artigo é fazer uma análise deste filme iluminando a culpa cristã historicamente atribuída à mulher e seus desdobramentos imediatos, como o feminicídio. PALAVRAS-CHAVE: Análise Fílmica; Cristianismo; Feminicídio; O Anticristo. ABSTRACT Antichrist, film of Lars von Trier, released on 2009, shows the the despair of a couple to lose their only son. Extremely controversial and fraught with biblical references - beginning with the title -, it’s a film that shocked the unyielding despair a bereaved mother that seems to carry the weight of the world on his wife's condition. The purpose of this paper is to analyze of this film illuminating the christian guilt historically attributed to the woman and their immediate consequences, like the feminicide. KEYWORDS: Filmic Analysis; Christianity; Feminicide; Antichrist. RESUMEN Anticristo, pelicula de Lars von Trier, lanzada em 2009, muestra el desespero de una pareja cuando pierde su único hijo. Extremadamente polémica y llena de referencias bíblicas - empezando con el título -, es una película que sorprende al inquebrantable desesperación de una madre em luto que parece cargar el peso del mundo por ser mujer. El objetivo de este artículo es analizar esta película iluminando la culpa cristiana históricamente asignada a las mujeres y sus consecuencias inmediatas, como el feminicidio. PALABRAS CLAVE: Análisis fílmica; Cristianismo; Feminicidio; Anticristo.
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Increasing the efficiency of photon collection in LArTPCs: the ARAPUCA light trap
Cancelo, G.; Cavanna, F.; Escobar, C. O.; Kemp, E.; Machado, A. A.; Para, A.; Segreto, E.; Totani, D.; Warner, D.
2018-03-01
The Liquid Argon Time Projection Chambers (LArTPCs) are a choice for the next generation of large neutrino detectors due to their optimal performance in particle tracking and calorimetry. The detection of Argon scintillation light plays a crucial role in the event reconstruction as well as the time reference for non-beam physics such as supernovae neutrino detection and baryon number violation studies. In this contribution, we present the current R&D work on the ARAPUCA (Argon R&D Advanced Program at UNICAMP), a light trap device to enhance Ar scintillation light collection and thus the overall performance of LArTPCs. The ARAPUCA working principle is based on a suitable combination of dichroic filters and wavelength shifters to achieve a high efficiency in light collection. We discuss the operational principles, the last results of laboratory tests and the application of the ARAPUCA as the alternative photon detection system in the protoDUNE detector.
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R&D Studies of the ATLAS LAr Calorimeter Readout Electronics for super-LHC
Chen, H
2010-01-01
The ATLAS Liquid Argon (LAr) calorimeters are high precision, high sensitivity and high granularity detectors, total about 180,000 signals are digitized and processed real-time on detector, to provide energy and time deposited in each detector element at every occurrence of the L1-trigger. A luminosity upgrade (x10) of the LHC will occur ~2017, the current readout electronics will have to be upgraded to sustain the higher radiation levels. A completely innovative readout scheme is being developed. The front-end readout will send out data continuously at each bunch crossing through high speed radiation resistant optical links, the data will be processed real-time with the possibility of implementing trigger algorithms. This article is an overview of the R&D activities and architectural studies the ATLAS LAr collaboration is developing: front-end analog and mixed-signal ASIC design, radiation resistance optical-links in SOS, high-speed back-end processing units based on FPGA architectures and power supply d...
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Strauch, B.; Heeschen, K. U.; Priegnitz, M.; Abendroth, S.; Spangenberg, E.; Thaler, J.; Schicks, J. M.
2015-12-01
The GFZ's LArge Reservoir Simulator LARS allows for the simulation of the 2008 Mallik gas hydrate production test and the comparison of fluid flow patterns and their driving forces. Do we see the gas flow pattern described for Mallik [Uddin, M. et al., J. Can. Petrol Tech, 50, 70-89, 2011] in a pilot scale test? If so, what are the driving forces? LARS has a network of temperature sensors and an electric resistivity tomography (ERT) enabling a good spatial resolution of gas hydrate occurrences, water and gas distribution, and changes in temperature in the sample. A gas flow meter and a water trap record fluid flow patterns and a backpressure valve has controlled the depressurization equivalent to the three pressure stages (7.0 - 5.0 - 4.2 MPa) applied in the Mallik field test. The environmental temperature (284 K) and confining pressure (13 MPa) have been constant. The depressurization induced immediate endothermic gas hydrate dissociation until re-establishment of the stability conditions by a consequent temperature decrease. Slight gas hydrate dissociation continued at the top and upper lateral border due to the constant heat input from the environment. Here transport pathways were short and permeability higher due to lower gas hydrate saturation. At pressures of 7.0 and 5.0 MPa the LARS tests showed high water flow rates and short irregular spikes of gas production. The gas flow patterns at 4.2 MPa and 3.0MPa resembled those of the Mallik test. In LARS the initial gas surges overlap with times of hydrate instability while water content and lengths of pathways had increased. Water production was at a minimum. A rapidly formed continuous gas phase caused the initial gas surges and only after gas hydrate dissociation decreased to a minimum the single gas bubbles get trapped before slowly coalescing again. In LARS, where pathways were short and no additional water was added, a transport of microbubbles is unlikely to cause a gas surge as suggested for Mallik.
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A space vehicle rotating with a uniform angu- lar velocity about a ...
Indian Academy of Sciences (India)
IAS Admin
A space vehicle rotating with a uniform angu- lar velocity about a vertical axis fixed to it is falling freely vertically downwards, say, with its engine shut off. It carries two astronauts inside it. One astronaut throws a tiny tool towards the other astronaut. The motion of the tiny tool with reference to a rotating frame rigidly fixed.
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AUTHOR|(SzGeCERN)758889; The ATLAS collaboration
2016-01-01
The ATLAS Liquid Argon (LAr) Calorimeters were designed and built to measure electromagnetic and hadronic energy in proton-proton collisions produced at the Large Hadron Collider (LHC) at centre-of-mass energies up to \\SI{14}{\\tera\\electronvolt} and instantaneous luminosities up to \\SI{d34}{\\per\\centi\\meter\\squared\\per\\second}. The High Luminosity LHC (HL-LHC) programme is now developed for up to 5-7 times the design luminosity, with the goal of accumulating an integrated luminosity of \\SI{3000}{\\per\\femto\\barn}. In the HL-LHC phase, the increased radiation levels require a replacement of the front-end (FE) electronics of the LAr Calorimeters. Furthermore, the ATLAS trigger system is foreseen to increase the trigger accept rate and the trigger latency which requires a larger data volume to be buffered. Therefore, the LAr Calorimeter read-out will be exchanged with a new FE and a high bandwidth back-end (BE) system for receiving data from all \
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DarkSide-20k: A 20 Tonne Two-Phase LAr TPC for Direct Dark Matter Detection at LNGS
Energy Technology Data Exchange (ETDEWEB)
Aalseth, C.E.; et al.
2017-07-25
Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid Argon Time Projection Chamber (LArTPC) with an active (fiducial) mass of 23 t (20 t). The DarkSide-20k LArTPC will be deployed within a shield/veto with a spherical Liquid Scintillator Veto (LSV) inside a cylindrical Water Cherenkov Veto (WCV). Operation of DarkSide-50 demonstrated a major reduction in the dominant $^{39}$Ar background when using argon extracted from an underground source, before applying pulse shape analysis. Data from DarkSide-50, in combination with MC simulation and analytical modeling, shows that a rejection factor for discrimination between electron and nuclear recoils of $\\gt3\\times10^9$ is achievable. This, along with the use of the veto system, is the key to unlocking the path to large LArTPC detector masses, while maintaining an "instrumental background-free" experiment, an experiment in which less than 0.1 events (other than $\
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Antonello, A.; Baibussinov, B.; Bilokon, H.; Boffelli, F.; Bonesini, M.; Calligarich, E.; Canci, N.; Centro, S.; Cesana, A.; Cieslik, K.; Cline, D.B.; Cocco, A.G.; Dequal, D.; Dermenev, A.; Dolfini, R.; De Gerone, M.; Dussoni, S.; Farnese, C.; Fava, A.; Ferrari, A.; Fiorillo, G.; Garvey, G.T.; Gatti, F.; Gibin, D.; Gninenko, S.; Guber, F.; Guglielmi, A.; Haranczyk, M.; Holeczek, J.; Ivashkin, A.; Kirsanov, M.; Kisiel, J.; Kochanek, I.; Kurepin, A.; Lagoda, J.; Lucchini, G.; Louis, W.C.; Mania, S.; Mannocchi, G.; Marchini, S.; Matveev, V.; Menegolli, A.; Meng, G.; Mills, G.B.; Montanari, C.; Nicoletto, M.; Otwinowski, S.; Palczewki, T.J.; Passardi, G.; Perfetto, F.; Picchi, P.; Pietropaolo, F.; Plonski, P.; Rappoldi, A.; Raselli, G.L.; Rossella, M.; Rubbia, C.; Sala, P.; Scaramelli, A.; Segreto, E.; Stefan, D.; Stepaniak, J.; Sulej, R.; Suvorova, O.; Terrani, M.; Tlisov, D.; Van de Water, R.G.; Trinchero, G.; Turcato, M.; Varanini, F.; Ventura, S.; Vignoli, C.; Wang, H.G.; Yang, X.; Zani, A.; Zaremba, K; Benettoni, M.; Bernardini, P.; Bertolin, A.; Brugnera, R.; Calabrese, M.; Cecchetti, A.; Cecchini, S.; Collazuol, G.; Creti, P.; Corso, F.Dal; Del Prete, A.; De Mitri, I.; De Robertis, G.; De Serio, M.; Esposti, L.Degli; Di Ferdinando, D.; Dore, U.; Dusini, S.; Fabbricatore, P.; Fanin, C.; Fini, R.A.; Fiore, G.; Garfagnini, A.; Giacomelli, G.; Giacomelli, R.; Guandalini, C.; Guerzoni, M.; Kose, U.; Laurenti, G.; Laveder, M.; Lippi, I.; Loddo, F.; Longhin, A.; Loverre, P.; Mancarella, G.; Mandrioli, G.; Margiotta, A.; Marsella, G.; Mauri, N.; Medinaceli, E.; Mengucci, A.; Mezzetto, M.; Michinelli, R.; Muciaccia, M.T.; Orecchini, D.; Paoloni, A.; Papadia, G.; Pastore, A.; Patrizii, L.; Pozzato, M.; Rosa, G.; Sahnounm, Z.; Simone, S.; Sioli, M.; Sirri, G.; Spurio, M.; Stanco, L.; Surdo, A.; Tenti, M.; Togo, V.; Ventura, M.; Zago, M.
2012-01-01
A new experiment with an intense ~2 GeV neutrino beam at CERN SPS is proposed in order to definitely clarify the possible existence of additional neutrino states, as pointed out by neutrino calibration source experiments, reactor and accelerator experiments and measure the corresponding oscillation parameters. The experiment is based on two identical LAr-TPCs complemented by magnetized spectrometers detecting electron and muon neutrino events at Far and Near positions, 1600 m and 300 m from the proton target, respectively. The ICARUS T600 detector, the largest LAr-TPC ever built with a size of about 600 ton of imaging mass, now running in the LNGS underground laboratory, will be moved at the CERN Far position. An additional 1/4 of the T600 detector (T150) will be constructed and located in the Near position. Two large area spectrometers will be placed downstream of the two LAr-TPC detectors to perform charge identification and muon momentum measurements from sub-GeV to several GeV energy range, greatly comple...
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Geometrik Yapıların İnşasında Pergel ve Çizgecin Kullanımı
Erduran, Ayten; Yeşildere, Sibel
2010-01-01
Bu yapıda üç matematik öğretinin pergel ve çizgeçmenin geometrik yapıları süreçleri incelenmektedir. Öğretmenlerin geometri yapı yapımı ve ilgili dersleri video kamera ile kaydedilmiş ve derslerdeki öğretmen-öğrenci-araç üçlüsü arasındaki etkileşim incelenmiştir. Ders Kitaplığı içeren öğretmenlerle görüşmeler yapıldı. Çalışmada üç matematik öğretmeninin pergel ve çizgeci geometrik yapılar yapı mühendisliği. Araştırma pergel ve çizgeçle geometrik yapıların inşasına ezbere bir anlayışla öğretme...
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Experimental observation of an extremely high electron lifetime with the ICARUS-T600 LAr-TPC
Antonello, M; Benetti, P; Boffelli, F; Bubak, A; Calligarich, E; Centro, S; Cesana, A; Cieslik, K; Cline, D B; Cocco, A G; Dabrowska, A; Dermenev, A; Dolfini, R; Falcone, A; Farnese, C; Fava, A; Ferrari, A; Fiorillo, G; Gibin, D; Gninenko, S; Guglielmi, A; Haranczyk, M; Holeczek, J; Kirsanov, M; Kisiel, J; Kochanek, I; Lagoda, J; Mania, S; Menegolli, A; Meng, G; Montanari, C; Otwinowski, S; Picchi, P; Pietropaolo, F; Plonski, P; Rappoldi, A; Raselli, G L; Rossella, M; Rubbia, C; Sala, P; Scaramelli, A; Segreto, E; Sergiampietri, F; Stefan, D; Sulej, R; Szarska, M; Terrani, M; Torti, M; Varanini, F; Ventura, S; Vignoli, C; Wang, H; Yang, X; Zalewska, A; Zani, A; Zaremba, K
2014-01-01
The ICARUS T600 detector, the largest liquid Argon Time Projection Chamber (LAr-TPC) realized after many years of RD activities, was installed and successfully operated for 3 years at the INFN Gran Sasso underground Laboratory. One of the most important issues was the need of an extremely low residual electronegative impurity content in the liquid Argon, in order to transport the free electrons created by the ionizing particles with a very small attenuation along the drift path. The solutions adopted for the Argon re-circulation and purification systems have permitted to reach impressive results in terms of Argon purity and a free electron lifetime exceeding 15 ms, corresponding to about 20 parts per trillion of equivalent O2 contamination, a milestone for any future project involving LAr-TPC's and the development of higher detector mass scales.
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Internet and Its Contributions to Library Services Internet: Kütüphane Hizmetlerine Katkıları
Directory of Open Access Journals (Sweden)
Yaşar Çelik
1995-06-01
Full Text Available This paper examines the major Internet services such as email, telnet and ftp and describes various information discovery and retrieval tools such as gopher, WAIS, and WWW. It also discusses the contributions of the Internet to library and information services. Bu makalede elektronik posta, telnet ve ftp gibi belli başlı Internet hizmetleri tanıtılmış, çeşitli bilgi keşfetme ve erişim araçları (gopher, WAIS, WWW açıklanmıştır. İnternet'in kütüphane hizmetlerine katkıları kısaca tartışılmıştır.
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LArGe: active background suppression using argon scintillation for the GERDA 0νββ-experiment
International Nuclear Information System (INIS)
Agostini, M.; Budjas, D.; Schoenert, S.; Barnabe-Heider, M.; Cattadori, C.; Gangapshev, A.; Gusev, K.; Heisel, M.; Smolnikov, A.; Junker, M.; Klimenko, A.; Lubashevskiy, A.; Pelczar, K.; Zuzel, G.
2015-01-01
LArGe is a GERDA low-background test facility to study novel background suppression methods in a low-background environment, for future application in the GERDA experiment. Similar to GERDA, LArGe operates bare germanium detectors submersed into liquid argon (1 m 3 , 1.4tons), which in addition is instrumented with photomultipliers to detect argon scintillation light. The scintillation signals are used in anti-coincidence with the germanium detectors to effectively suppress background events that deposit energy in the liquid argon. The background suppression efficiency was studied in combination with a pulse shape discrimination (PSD) technique using a BEGe detector for various sources, which represent characteristic backgrounds to GERDA. Suppression factors of a few times 10 3 have been achieved. First background data of LArGe with a coaxial HPGe detector (without PSD) yield a background index of (0.12 - 4.6) x 10 -2 cts/(keV kg year) (90 % C.L.), which is at the level of GERDA Phase I. Furthermore, for the first time we monitor the natural 42 Ar abundance (parallel to GERDA), and have indication for the 2νββ-decay in natural germanium. These results show the effectivity of an active liquid argon veto in an ultra-low background environment. As a consequence, the implementation of a liquid argon veto in GERDA Phase II is pursued. (orig.)
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LArGe: active background suppression using argon scintillation for the Gerda 0ν β β -experiment
Agostini, M.; Barnabé-Heider, M.; Budjáš, D.; Cattadori, C.; Gangapshev, A.; Gusev, K.; Heisel, M.; Junker, M.; Klimenko, A.; Lubashevskiy, A.; Pelczar, K.; Schönert, S.; Smolnikov, A.; Zuzel, G.
2015-10-01
LArGe is a Gerda low-background test facility to study novel background suppression methods in a low-background environment, for future application in the Gerda experiment. Similar to Gerda, LArGe operates bare germanium detectors submersed into liquid argon (1 m^3, 1.4 tons), which in addition is instrumented with photomultipliers to detect argon scintillation light. The scintillation signals are used in anti-coincidence with the germanium detectors to effectively suppress background events that deposit energy in the liquid argon. The background suppression efficiency was studied in combination with a pulse shape discrimination (PSD) technique using a BEGe detector for various sources, which represent characteristic backgrounds to Gerda. Suppression factors of a few times 10^3 have been achieved. First background data of LArGe with a coaxial HPGe detector (without PSD) yield a background index of (0.12-4.6)× 10^{-2} cts/(keV kg year) (90 % C.L.), which is at the level of Gerda Phase I. Furthermore, for the first time we monitor the natural ^{42}Ar abundance (parallel to Gerda), and have indication for the 2ν β β -decay in natural germanium. These results show the effectivity of an active liquid argon veto in an ultra-low background environment. As a consequence, the implementation of a liquid argon veto in Gerda Phase II is pursued.
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LArGe: active background suppression using argon scintillation for the GERDA 0νββ-experiment
Energy Technology Data Exchange (ETDEWEB)
Agostini, M.; Budjas, D.; Schoenert, S. [Technische Universitaet Muenchen, Munich (Germany); Barnabe-Heider, M. [Technische Universitaet Muenchen, Munich (Germany); Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Cattadori, C. [Universita degli Studi di Milano, Milan (Italy); INFN, Milan (Italy); Gangapshev, A. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Institut for Nuclear Research, Moscow (Russian Federation); Gusev, K. [Technische Universitaet Muenchen, Munich (Germany); Joint Institut for Nuclear Research, Dubna (Russian Federation); National Research Center Kurchatov Institut, Moscow (Russian Federation); Heisel, M.; Smolnikov, A. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Junker, M. [Laboratori Nazionali del Gran Sasso, Assergi (Italy); Klimenko, A.; Lubashevskiy, A. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Joint Institut for Nuclear Research, Dubna (Russian Federation); Pelczar, K. [Jagellonian University, Cracow (Poland); Zuzel, G. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Jagellonian University, Cracow (Poland)
2015-10-15
LArGe is a GERDA low-background test facility to study novel background suppression methods in a low-background environment, for future application in the GERDA experiment. Similar to GERDA, LArGe operates bare germanium detectors submersed into liquid argon (1 m{sup 3}, 1.4tons), which in addition is instrumented with photomultipliers to detect argon scintillation light. The scintillation signals are used in anti-coincidence with the germanium detectors to effectively suppress background events that deposit energy in the liquid argon. The background suppression efficiency was studied in combination with a pulse shape discrimination (PSD) technique using a BEGe detector for various sources, which represent characteristic backgrounds to GERDA. Suppression factors of a few times 10{sup 3} have been achieved. First background data of LArGe with a coaxial HPGe detector (without PSD) yield a background index of (0.12 - 4.6) x 10{sup -2} cts/(keV kg year) (90 % C.L.), which is at the level of GERDA Phase I. Furthermore, for the first time we monitor the natural {sup 42}Ar abundance (parallel to GERDA), and have indication for the 2νββ-decay in natural germanium. These results show the effectivity of an active liquid argon veto in an ultra-low background environment. As a consequence, the implementation of a liquid argon veto in GERDA Phase II is pursued. (orig.)
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Development of new readout electronics for the ATLAS LAr Calorimeter at the sLHC
Strässner, A
2009-01-01
The readout of the ATLAS Liquid Argon (LAr) calorimeter is a complex multi-channel system to amplify, shape, digitize and process signals of the detector cells. The current on-detector electronics is not designed to sustain the ten times higher radiation levels expected at sLHC in the years beyond 2019/2020, and will be replaced by new electronics with a completely different readout scheme. The future on-detector electronics is planned to send out all data continuously at each bunch crossing, as opposed to the current system which only transfers data at a trigger-accept signal. Multiple high-speed and radiation-resistant optical links will transmit 100 Gb/s per front-end board. The off-detector processing units will not only process the data in real-time and provide digital data buffering, but will also implement trigger algorithms. An overview about the various components necessary to develop such a complex system is given. The current R&D activities and architectural studies of the LAr Calorimeter group...
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Hils, Maximilian; The ATLAS collaboration
2015-01-01
The ATLAS Liquid Argon (LAr) Calorimeters were designed and built to measure electromagnetic and hadronic energy in proton-proton collisions produced at the LHC at centre-of-mass energies up to 14 TeV and instantaneous luminosities up to $10^{34} \\text{cm}^{-2} \\text{s}^{-1}$. The High Luminosity LHC (HL-LHC) programme is now developed for up to 5-7 times the design luminosity, with the goal of accumulating an integrated luminosity of $3000~\\text{fb}^{-1}$. In the HL-LHC phase, the increased radiation levels require a replacement of the front-end electronics of the LAr Calorimeters. Furthermore, the ATLAS trigger system is foreseen to increase the trigger accept rate by a factor 10 to 1 MHz and the trigger latency by a factor of 20 which requires a larger data volume to be buffered. Therefore, the LAr Calorimeter read-out will be exchanged with a new front-end and a high bandwidth back-end system for receiving data from all 186.000 channels at 40 MHz LHC bunch-crossing frequency and for off-detector buffering...
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Directory of Open Access Journals (Sweden)
najmeh khalili
2016-10-01
Full Text Available Introduction:Many existing results on water and agriculture researches require long-term statistical climate data, while practically; the available collected data in synoptic stations are quite short. Therefore, the required daily climate data should be generated based on the limited available data. For this purpose, weather generators can be used to enlarge the data length. Among the common weather generators, two models are more common: LARS-WG and ClimGen. Different studies have shown that these two models have different results in different regions and climates. Therefore, the output results of these two methods should be validated based on the climate and weather conditions of the study region. Materials and Methods:The Sisab station is 35 KM away from Bojnord city in Northern Khorasan. This station was established in 1366 and afterwards, the meteorological data including precipitation data are regularly collected. Geographical coordination of this station is 37º 25׳ N and 57º 38׳ E, and the elevation is 1359 meter. The climate in this region is dry and cold under Emberge and semi-dry under Demarton Methods. In this research, LARG-WG model, version 5.5, and ClimGen model, version 4.4, were used to generate 500 data sample for precipitation and temperature time series. The performance of these two models, were evaluated using RMSE, MAE, and CD over the 30 years collected data and their corresponding generated data. Also, to compare the statistical similarity of the generated data with the collected data, t-student, F, and X2 tests were used. With these tests, the similarity of 16 statistical characteristics of the generated data and the collected data has been investigated in the level of confidence 95%. Results and Discussion:This study showed that LARS-WG model can better generate precipitation data in terms of statistical error criteria. RMSE and MAE for the generated data by LAR-WG were less than ClimGen model while the CD value of
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Empirical Asset Pricing: Eugene Fama, Lars Peter Hansen, and Robert Shiller
Campbell, John Y.
2016-01-01
The Nobel Memorial Prize in Economic Sciences for 2013 was awarded to Eugene Fama, Lars Peter Hansen, and Robert Shiller for their contributions to the empirical study of asset pricing. Some observers have found it hard to understand the common elements of the laureates research, preferring to highlight areas of disagreement among them. This paper argues that empirical asset pricing is a coherent enterprise, which owes much to the laureates seminal contributions, and that important themes in ...
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TÜRKMEN, Lütfullah; ÇARDAK, Osman; DIKMENLI, Musa
2014-01-01
İlk ve orta öğrenim fen bilimleri eğitiminde, öğrencilerin sahip oldukları kavram yanılgılarını değiştirmek için öğretmenler ve fen bilimleri eğitimcileri tarafından farklı öğretim yöntemleri kullanılmaktadır. Kavram yanılgılarını değiştirmek kullanılan en yaygın olan yöntemlerden biri de kavram haritalarıdır. Bu çalışmanın amacı Lise 1. sınıf biyoloji dersi alan öğrencilerin Canlıların çeşitliliği ve sınıflandırılması hakkındaki kavram yanılgılarını değiştirmektir. Bu çalışma biyoloji dersi...
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Altındere Vadisi Milli Parkı kullanıcılarının rekreasyonel memnuniyetinin belirlenmesi
Directory of Open Access Journals (Sweden)
Özge Volkan AKSU
2017-07-01
Full Text Available Bu çalışma; Altındere Vadisi Milli Parkı kullanıcılarının rekreasyonel memnuniyetinin belirlenmesi amacı ile 2015 yılı yaz dönemi milli park alanında, 308 yerli kullanıcı ile yapılan anket çalışmalarını kapsamaktadır. Anket soruları ile kullanıcılarının bazı kişisel özellikleri, kullanım tercihleri, katıldıkları rekreasyonel etkinlikler, geliş amaçları, alan tercihleri, genel ve beklenen memnuniyetleri, alan farkındalığı, kullanıcı memnuniyet ve memnuniyetsizlik durumunu etkileyen faktörler ve bu faktörlerle kullanıcıların bazı kişisel özellikleri arasındaki ilişkiler istatistiksel yöntemlerle irdelenmiştir. Sonuç olarak; “milli parkın doğal ve kültürel peyzaj değerleri, görsel kalite”, “alandan aktif olarak yararlanma isteği”, “alandan pasif olarak yararlanma isteği”, “macera ve kendini keşfetme”, “açık hava aktivite olanakları”, “sosyalleşme”, “ulaşılabilirlik ve alan kullanımı” olarak tanımlanabilecek faktörlerin alandaki kullanıcı memnuniyeti üzerinde etkili olduğu, yine; “planlama-tasarım sorunları”, “donatı elemanı eksikliği, yönetim”, “taşıma kapasitesinin aşılması-kalabalık, gürültü kirliliği”, “çevre-görüntü kirliliği, alt yapı-bakım eksikliği”, “bilgi eksikliği ve yönetim” olarak tanımlanabilecek faktörlerin ise kullanıcı memnuniyetsizliği üzerinde etkili olduğu belirlenmiştir. Kullanıcıların genel memnuniyet ve beklentilerinin karşılanma durumu orta düzeydir. Kullanıcıların memnuniyet faktörlerinin, geldiği yerin milli parka uzaklığı ve eğitim, memnuniyetsizlik faktörlerinin ise geldiği yerin milli parka uzaklığı, cinsiyet ve yaş olarak belirlenen etmenlerden etkilendiği saptanmıştır.
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Labores, quitutes e panelas: em busca do lar ideal
Pilla,Maria Cecília Barreto Amorim
2008-01-01
A partir do conceito de auto-governo, entendido como um modelo psicológico capaz de garantir o reconhecimento e respeito do próximo, uma valorização de si mesmo, este artigo propõe uma reflexão a respeito da mulher no desempenho do papel de "rainha do lar" no Brasil do início do século XX. Na preparação da casa repousava a valorização de uma conduta controlada da dona-de-casa, que deveria manter o controle sobre tudo e sobre todos, tendo aí a oportunidade de demonstrar sua capacidade de gover...
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Operation of bare HPGe detectors in LAr/LN{sub 2} for the GERDA experiment
Energy Technology Data Exchange (ETDEWEB)
Heider, M Barnabe; Chkvorets, O; Schoenert, S [MPI fuer Kernphysik, Heidelberg (Germany); Cattadori, C [INFN-Milano Bicocca, Milano (Italy); Vacri, A di [INFN-LNGS, L' Aquila (Italy); Gusev, K; Shirchenko, M [Russian Research Center Kurchatov Institute, Moscow, Russia and JINR, Dubna (Russian Federation)], E-mail: assunta.divacri@lngs.infn.it
2008-11-01
GERDA is designed to search for 0{nu}{beta}{beta}-decay of {sup 76}Ge using high purity germanium detectors (HPGe), enriched ({approx} 85%) in {sup 76}Ge, directly immersed in LAr which acts both as shield against {gamma} radiation and as cooling medium. The cryostat is located in a stainless steel water tank providing an additional shield against external background. The GERDA experiment aims at a background (b) {approx}<10{sup -3} cts/(kg-y-keV) and energy resolution (FWHM) {<=} 4 keV at Q{sub {beta}}{sub {beta}} = 2039 keV. GERDA experiment is foreseen to proceed in two phases. For Phase I, eight reprocessed enriched HPGe detectors from the past HdM [C Balysh et al., Phys. Rev. D 66 (1997) 54] and IGEX [C E Aalseth et al., Phys. of Atomic Nuclei 63 (2000) 1225] experiments ({approx} 18 kg) and six reprocessed natural HPGe detectors ({approx} 15 kg) from the Genius Test-Facility [H V Klapdor et al., HIM A 481 (2002) 149] will be deployed in strings. GERDA aims at b {approx}< 10{sup -2} cts/(kg{center_dot}keV{center_dot}y). With an exposure of {approx} 15 kg{center_dot}y of {sup 76}Ge and resolution {approx} 3.6 keV, the sensitivity on the half-life will be T{sup 0{nu}}{sub 1/2} 3 {center_dot} 10{sup 25} y (90 % C.L.) corresponding to m{sub ee} < 270 meV [V A Rodin et al., Nucl. Phys. A 766 (2006) 107]. In Phase II, new diodes, able to discriminate between single- and multi-site events, will be added ({approx} 20 kg of {sup 76}Ge with intrinsic b {approx} 10{sup -2} cts/(kg{center_dot}keV{center_dot}y). With an exposure of {approx} 120 kg{center_dot}y, it is expected T{sup 0{nu}}{sub 1/2} > 1.5 {center_dot} 10{sup 26} y (90% C.L.) corresponding to m{sub ee} < 110 meV [V A Rodin et al., Nucl. Phys. A 766 (2006) 107]. Three natural p-type HPGe prototypes (different passivation layer designs) are available in the GERDA underground facility at LNGS to investigate the effect of the detector assembly (low-mass low-activity holder), of the handling procedure and of the
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Directory of Open Access Journals (Sweden)
Yaşar Tonta
2009-12-01
Full Text Available Facebook, MySpace, Flickr and YouTube are currently among the most frequently visited websites with Web 2.0 features. They are used not only for social networking and entertainment but also for access to information, for learning and for carrying out professional work. Social networks commonly have Web 2.0 features, offer personalized services and allow users to incorporate their own content easily and describe, organize and share it with others, thereby enriching users’ experience. Some users tend to “live” on those social networks and expect information providing organizations to offer similar services. They want libraries to be as accessible, flexible, open to collaboration and sharing as that of social networks and heighten the expectations from such institutions. The future of libraries is closely associated with how successfully they meet the demands of digital users. Otherwise, the “net generation” or the “digital natives” grown up with the Web, Google and Facebook would see libraries as outdated institutions and “take their business elsewhere” to satisfy their information needs. In this paper, the impact of the technological convergence on information providing organizations is reviewed and the challenges and opportunities facing libraries in the digital environment are discussed. Facebook, MySpace, Flickr ve YouTube gibi Web 2.0 özelliklerine sahip sosyal ağlar en çok ziyaret edilen web siteleri arasında yer almaktadır. Sosyal ağlar sadece sosyalleşmek ve eğlenmek amacıyla değil, bilgiye erişmek, öğrenmek ve profesyonel iş yapmak amacıyla da kullanılmaktadır. Sosyal ağların sağladığı işbirliği, kişiselleştirme, kullanıcı destekli içerik ekleme ve üst veri gibi özellikler kullanıcı deneyimini zenginleştirmekte ve bu web sitelerini daha çekici kılmaktadır. Kütüphanelerin de sosyal ağlar kadar erişilebilir, esnek, işbirliği ve paylaşıma açık olmasını bekleyen kullanıcılar
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Ögenler, Oya; Yapıcı, Gülçin
2011-01-01
Özet Amaç. Tıp, batıl ve dini inançlar belli bir toplumda sözlü veya yazılı bir şekilde nesilden nesile aktarılır. Tıp, batıl inançlar ve din birbirinden bazen kesin çizgilerle ayrılırken bazen aralarındaki sınır belirsizleşebilmektedir. Bu üçlüden herhangi birine ait davranışa neden olan bilgi zamanla değişime uğrar başlangıç noktası unutulur ama varlığını sürdürür. Doğru oldukları için değil, işe yaradıkları için doğru kabul edilen birçok inanış insanları belirsizlikten kurtarır, iç rahatla...
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Ingicco, Thomas; de Vos, John; Huffman, O Frank
2014-01-01
A fossil femur excavated by Eugène Dubois between 1891-1900 in the Lower/Middle Pleistocene bonebed of the Trinil site (Java, Indonesia) was recognised by us as that of a Hylobatidae. The specimen, Trinil 5703 of the Dubois Collection (Leiden, The Netherlands), has the same distinctive form of fossilization that is seen in many of the bonebed fossils from Trinil in the collection. Anatomical comparison of Trinil 5703 to a sample of carnivore and primate femora, supported by morphometric analyses, lead to the attribution of the fossil to gibbon. Trinil 5703 therefore provides the oldest insular record of this clade, one of the oldest known Hylobatidae fossils from Southeast Asia. Because living Hylobatidae only inhabit evergreen rain forests, the paleoenvironment within the river drainage in the greater Trinil area evidently included forests of this kind during the Lower/Middle Pleistocene as revealed here.
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DarkSide-20k: A 20 tonne two-phase LAr TPC for direct dark matter detection at LNGS
Aalseth, C. E.; Acerbi, F.; Agnes, P.; Albuquerque, I. F. M.; Alexander, T.; Alici, A.; Alton, A. K.; Antonioli, P.; Arcelli, S.; Ardito, R.; Arnquist, I. J.; Asner, D. M.; Ave, M.; Back, H. O.; Barrado Olmedo, A. I.; Batignani, G.; Bertoldo, E.; Bettarini, S.; Bisogni, M. G.; Bocci, V.; Bondar, A.; Bonfini, G.; Bonivento, W.; Bossa, M.; Bottino, B.; Boulay, M.; Bunker, R.; Bussino, S.; Buzulutskov, A.; Cadeddu, M.; Cadoni, M.; Caminata, A.; Canci, N.; Candela, A.; Cantini, C.; Caravati, M.; Cariello, M.; Carlini, M.; Carpinelli, M.; Castellani, A.; Catalanotti, S.; Cataudella, V.; Cavalcante, P.; Cavuoti, S.; Cereseto, R.; Chepurnov, A.; Cicalò, C.; Cifarelli, L.; Citterio, M.; Cocco, A. G.; Colocci, M.; Corgiolu, S.; Covone, G.; Crivelli, P.; D'Antone, I.; D'Incecco, M.; D'Urso, D.; Da Rocha Rolo, M. D.; Daniel, M.; Davini, S.; de Candia, A.; De Cecco, S.; De Deo, M.; De Filippis, G.; De Guido, G.; De Rosa, G.; Dellacasa, G.; Della Valle, M.; Demontis, P.; Derbin, A.; Devoto, A.; Di Eusanio, F.; Di Pietro, G.; Dionisi, C.; Dolgov, A.; Dormia, I.; Dussoni, S.; Empl, A.; Fernandez Diaz, M.; Ferri, A.; Filip, C.; Fiorillo, G.; Fomenko, K.; Franco, D.; Froudakis, G. E.; Gabriele, F.; Gabrieli, A.; Galbiati, C.; Garcia Abia, P.; Gendotti, A.; Ghisi, A.; Giagu, S.; Giampa, P.; Gibertoni, G.; Giganti, C.; Giorgi, M. A.; Giovanetti, G. K.; Gligan, M. L.; Gola, A.; Gorchakov, O.; Goretti, A. M.; Granato, F.; Grassi, M.; Grate, J. W.; Grigoriev, G. Y.; Gromov, M.; Guan, M.; Guerra, M. B. B.; Guerzoni, M.; Gulino, M.; Haaland, R. K.; Hallin, A.; Harrop, B.; Hoppe, E. W.; Horikawa, S.; Hosseini, B.; Hughes, D.; Humble, P.; Hungerford, E. V.; Ianni, An.; Jillings, C.; Johnson, T. N.; Keeter, K.; Kendziora, C. L.; Kim, S.; Koh, G.; Korablev, D.; Korga, G.; Kubankin, A.; Kuss, M.; Kuźniak, M.; La Commara, M.; Lehnert, B.; Li, X.; Lissia, M.; Lodi, G. U.; Loer, B.; Longo, G.; Loverre, P.; Lussana, R.; Luzzi, L.; Ma, Y.; Machado, A. A.; Machulin, I. N.; Mandarano, A.; Mapelli, L.; Marcante, M.; Margotti, A.; Mari, S. M.; Mariani, M.; Maricic, J.; Martoff, C. J.; Mascia, M.; Mayer, M.; McDonald, A. B.; Messina, A.; Meyers, P. D.; Milincic, R.; Moggi, A.; Moioli, S.; Monroe, J.; Monte, A.; Morrocchi, M.; Mount, B. J.; Mu, W.; Muratova, V. N.; Murphy, S.; Musico, P.; Nania, R.; Navrer Agasson, A.; Nikulin, I.; Nosov, V.; Nozdrina, A. O.; Nurakhov, N. N.; Oleinik, A.; Oleynikov, V.; Orsini, M.; Ortica, F.; Pagani, L.; Pallavicini, M.; Palmas, S.; Pandola, L.; Pantic, E.; Paoloni, E.; Paternoster, G.; Pavletcov, V.; Pazzona, F.; Peeters, S.; Pelczar, K.; Pellegrini, L. A.; Pelliccia, N.; Perotti, F.; Perruzza, R.; Pesudo, V.; Piemonte, C.; Pilo, F.; Pocar, A.; Pollmann, T.; Portaluppi, D.; Pugachev, D. A.; Qian, H.; Radics, B.; Raffaelli, F.; Ragusa, F.; Razeti, M.; Razeto, A.; Regazzoni, V.; Regenfus, C.; Reinhold, B.; Renshaw, A. L.; Rescigno, M.; Retière, F.; Riffard, Q.; Rivetti, A.; Rizzardini, S.; Romani, A.; Romero, L.; Rossi, B.; Rossi, N.; Rubbia, A.; Sablone, D.; Salatino, P.; Samoylov, O.; Sánchez García, E.; Sands, W.; Sanfilippo, S.; Sant, M.; Santorelli, R.; Savarese, C.; Scapparone, E.; Schlitzer, B.; Scioli, G.; Segreto, E.; Seifert, A.; Semenov, D. A.; Shchagin, A.; Shekhtman, L.; Shemyakina, E.; Sheshukov, A.; Simeone, M.; Singh, P. N.; Skensved, P.; Skorokhvatov, M. D.; Smirnov, O.; Sobrero, G.; Sokolov, A.; Sotnikov, A.; Speziale, F.; Stainforth, R.; Stanford, C.; Suffritti, G. B.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Tonazzo, A.; Tosi, A.; Trinchese, P.; Unzhakov, E. V.; Vacca, A.; Vázquez-Jáuregui, E.; Verducci, M.; Viant, T.; Villa, F.; Vishneva, A.; Vogelaar, B.; Wada, M.; Wahl, J.; Walding, J.; Wang, H.; Wang, Y.; Watson, A. W.; Westerdale, S.; Williams, R.; Wojcik, M. M.; Wu, S.; Xiang, X.; Xiao, X.; Yang, C.; Ye, Z.; Yllera de Llano, A.; Zappa, F.; Zappalà, G.; Zhu, C.; Zichichi, A.; Zullo, M.; Zullo, A.; Zuzel, G.
2018-03-01
Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid Argon Time Projection Chamber (LAr TPC) with an active (fiducial) mass of 23 t (20 t). This paper describes a preliminary design for the experiment, in which the DarkSide-20k LAr TPC is deployed within a shield/veto with a spherical Liquid Scintillator Veto (LSV) inside a cylindrical Water Cherenkov Veto (WCV). This preliminary design provides a baseline for the experiment to achieve its physics goals, while further development work will lead to the final optimization of the detector parameters and an eventual technical design. Operation of DarkSide-50 demonstrated a major reduction in the dominant 39Ar background when using argon extracted from an underground source, before applying pulse shape analysis. Data from DarkSide-50, in combination with MC simulation and analytical modeling, shows that a rejection factor for discrimination between electron and nuclear recoils of >3 × 109 is achievable. This, along with the use of the veto system and utilizing silicon photomultipliers in the LAr TPC, are the keys to unlocking the path to large LAr TPC detector masses, while maintaining an experiment in which less than < 0.1 events (other than ν-induced nuclear recoils) is expected to occur within the WIMP search region during the planned exposure. DarkSide-20k will have ultra-low backgrounds than can be measured in situ, giving sensitivity to WIMP-nucleon cross sections of 1.2 × 10^{-47} cm2 (1.1 × 10^{-46} cm2) for WIMPs of 1 TeV/c 2 (10 TeV/c 2) mass, to be achieved during a 5 yr run producing an exposure of 100 t yr free from any instrumental background.
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Energy Technology Data Exchange (ETDEWEB)
Adams, C.; et al.
2018-04-07
The single-phase liquid argon time projection chamber (LArTPC) provides a large amount of detailed information in the form of fine-grained drifted ionization charge from particle traces. To fully utilize this information, the deposited charge must be accurately extracted from the raw digitized waveforms via a robust signal processing chain. Enabled by the ultra-low noise levels associated with cryogenic electronics in the MicroBooNE detector, the precise extraction of ionization charge from the induction wire planes in a single-phase LArTPC is qualitatively demonstrated on MicroBooNE data with event display images, and quantitatively demonstrated via waveform-level and track-level metrics. Improved performance of induction plane calorimetry is demonstrated through the agreement of extracted ionization charge measurements across different wire planes for various event topologies. In addition to the comprehensive waveform-level comparison of data and simulation, a calibration of the cryogenic electronics response is presented and solutions to various MicroBooNE-specific TPC issues are discussed. This work presents an important improvement in LArTPC signal processing, the foundation of reconstruction and therefore physics analyses in MicroBooNE.
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Energy Technology Data Exchange (ETDEWEB)
Budjas, Dusan [Physik-Department E15, Technische Universitaet Muenchen (Germany); Collaboration: GERDA-Collaboration
2014-07-01
LArGe is a low background test facility used for proving innovative approaches to background reduction in support of the neutrinoless double beta decay experiment Gerda. These approaches include an anti-Compton veto using scintillation light detection from liquid argon, as well as a novel pulse shape discrimination method exploiting the characteristic electrical field distribution inside BEGe detectors. The latter technique can identify single-site events (typical for double beta decays) and efficiently reject multi-site events (typical for backgrounds from gamma-ray interactions), as well as different types of background events from detector surfaces. While the main focus of the LArGe facility is to assist with reaching the goal of Gerda - improving the sensitivity for {sup 76}Ge neutrinoless double beta decay search, reducing the background at low energies and lowering the energy threshold is also of interest. In particular such efforts can be potentially relevant for search of dark matter or low energy neutrino interactions. In this talk I present the experimental measurement of the low energy region with a BEGe detector operated in LArGe with the application of powerful background suppression methods. The performance will be compared to that of some dedicated dark matter detection experiments.
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Avaliação laríngea em pacientes reumatológicos Laryngeal assessment in reumatic disease patients
Directory of Open Access Journals (Sweden)
Hugo Valter Lisboa Ramos
2005-08-01
Full Text Available As doenças reumáticas produzem alterações sistêmicas e podem, por isso, comprometer os vasos sangüíneos, as serosas e as mucosas de todo o trato aerodigestivo. Casos esporádicos de acometimento laríngeo por doenças reumáticas têm sido descritos. Esse estudo tem por objetivo avaliar e descrever as alterações laríngeas encontradas em pacientes reumatológicos. FORMA DE ESTUDO: coorte transversal. MATERIAL E MÉTODO: Estudo transversal com pacientes portadores de lúpus eritematoso sistêmico, esclerodermia e doença mista do tecido conjuntivo. Os pacientes submeteram-se a exame clínico otorrinolaringológico e à videolaringoestroboscopia. RESULTADOS: Foram incluídos no estudo 27 pacientes sendo que 26 conseguiram realizar a videolaringoestroboscopia. Alterações laríngeas foram observadas em 11 dos 12 pacientes portadores de lúpus, nos 11 pacientes portadores de esclerodermia e nos 3 pacientes portadores de doença mista do tecido conjuntivo. Lesões sugestivas de nódulo em bambu foram identificados em 5 pacientes e 92,3% dos pacientes apresentaram sinais laríngeos de síndrome faringolaríngea do refluxo. CONCLUSÃO: Neste estudo identificamos 5 lesões sugestivas de nódulos em bambu e sinais laríngeos de refluxo em quase todos os pacientes.Rheumatic diseases usually promote several systemic disorders, which can affect blood vessels, mucosa and serosa of the aerodigestive tract. Scarce laryngeal involvement has been described in these patients and this study aims at investigating laryngeal alterations found in patients with rheumatic diseases. STUDY DESIGN: transversal cohort. MATERIAL AND METHOD: A transversal study was developed with systemic lupus erythematous, systemic sclerosis and mixed connective tissue disease's patients. They were evaluated by means of clinical examinations and videolaryngoestroboscopy. RESULTS: Twenty-seven patients were included in the study, 26 succeeded in completing the
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Lise Öğrencilerinin Mobil Öğrenme Araçlarını Kullanma Öz-Yeterlik Düzeylerinin İncelenmesi
Karaoğlan Yılmaz, Fatma Gizem; Dilen, Anıl; Yılmaz, Hatice
2018-01-01
Bu araştırmanın amacı, lise öğrencilerinin mobil öğrenme araçlarını kullanma öz-yeterlik düzeylerini; sınıf düzeyine, cinsiyete, internette geçirilen zamana ve düzenli internet bağlantısına sahip olup olmama durumuna göre incelemektir. Araştırma kapsamında, lise öğrencilerinin mobil öğrenme araçlarını kullanma öz-yeterlik düzeylerini inceleyebilmek için tarama modeli kullanılmıştır. Araştırmanın katılımcıları; 2016-2017 öğretim yılı güz döneminde bir lisede öğrenim görmekte olan ve mobil öğre...
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Kullanıcıların Facebook Reklamlarına Tepkilerini Belirleyen Reklam Özellikleri
Çakır, Vesile; Tam, Mehmet Sinan
2014-01-01
Facebook halihazırda en popüler sosyal medyadır ve bu özelliği ile cazip bir reklam medyasıdır. Bu araştırma facebook reklamlarının beğenilmesi, tıklanması ve paylaşılmasında yordayıcı olan reklam özelliklerini araştırmaktadır. Facebook kullanıcıları üzerinde gerçekleştirilen bir saha araştırmasından elde edilen veriler, kullanıcıların ilgilendikleri bir ürün kategorisine ait, tıklanma oranının yüksek, bilim kurgu tarzı, değişik renk ve yazılı bağlantılara sahip ödemeli reklamlara daha çok tı...
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Soft error rate estimations of the Kintex-7 FPGA within the ATLAS Liquid Argon (LAr) Calorimeter
International Nuclear Information System (INIS)
Wirthlin, M J; Harding, A; Takai, H
2014-01-01
This paper summarizes the radiation testing performed on the Xilinx Kintex-7 FPGA in an effort to determine if the Kintex-7 can be used within the ATLAS Liquid Argon (LAr) Calorimeter. The Kintex-7 device was tested with wide-spectrum neutrons, protons, heavy-ions, and mixed high-energy hadron environments. The results of these tests were used to estimate the configuration ram and block ram upset rate within the ATLAS LAr. These estimations suggest that the configuration memory will upset at a rate of 1.1 × 10 −10 upsets/bit/s and the bram memory will upset at a rate of 9.06 × 10 −11 upsets/bit/s. For the Kintex 7K325 device, this translates to 6.85 × 10 −3 upsets/device/s for configuration memory and 1.49 × 10 −3 for block memory
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Borah, Manash Pratim; Prasad, Surya Bali
2017-06-30
India has an immense faunal, floral, as well as cultural diversity with many ethnic communities who are primarily dependent on the traditional medicinal system for their primary health care. Documentation and evaluation of this indigenous remedial knowledge may be helpful to establish new drugs for human health. The present study is intended to look into different zootherapeutic medicinal uses in the traditional health care system among the native inhabitants adjacent to the Gibbon Wildlife Sanctuary, Assam, India. Field survey was carried out from March 2015 to August 2015 by personal interviews through semi-structured questionnaires. In some cases where participants were uncomfortable with the questionnaires, informal interviews and open group discussions were conducted with a total of 62 indigenous respondents (43 male and 19 female) who provided the information regarding various medicinal uses of animals and their products (local name of animal, mode of preparation, application etc). The study recorded a total of 44 different species, 44 genera and 36 families of animals which are used for the treatment of 40 different ailments. Insects occupied the highest uses (30.9%), followed by mammals (23.8%), fishes (16.7%), reptiles (11.9%), amphibians (7.1%), annelids (4.8%) and gastropods (4.8%). Further, some zootherapeutic animals i.e. cockroach (Periplaneta americana), praying mantis (Mantis religiosa) and earthworms (Metaphire houletti, Pheretima posthum) are used for the treatment of asthma, otorrhoea and cancer respectively. The findings suggest that the traditional zootherapeutic remedial measures followed by the native people adjacent to Gibbon Wildlife Sanctuary plays an important role in their primary health care. The documentation of this indigenous knowledge on animal based medicines should be very helpful in the formulation of strategies for sustainable management and conservation of bio-resources as well as providing potential for the novel drugs
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Review of Politics as Form in Lars von Trier: A Post-Brechtian Reading
Directory of Open Access Journals (Sweden)
Sara Marino
2014-10-01
Full Text Available Controversial and unconventional designer of formal experimentations, simultaneously celebrated and despised around the world, performative to a point that realism is achieved through the manipulation of realistic conventions hidden in everyday forms of human interactions, von Trier is indeed one of the most important contemporary filmmakers within European cinema, as well as the protagonist of Koutsourakis’s Politics as Form in Lars von Trier: A Post-Brechtian Reading.
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Background suppression in Gerda Phase II and its study in the LArGe low background set-up
Energy Technology Data Exchange (ETDEWEB)
Budjas, Dusan [Physik-Department E15, Technische Universitaet Muenchen (Germany); Collaboration: GERDA-Collaboration
2013-07-01
In Phase II of the Gerda experiment additional ∝20 kg of BEGe-type germanium detectors, enriched in {sup 76}Ge, will be deployed in liquid argon (LAr) to further increase the sensitivity for the half-life of neutrinoless double beta (0νββ) decay of {sup 76}Ge to > 2 . 10{sup 26} yr. To reduce background by a factor of 10 to the required level of < 10{sup -3} cts/(keV.kg.yr), it is necessary to employ active background-suppression techniques, including anti-Compton veto using scintillation light detection from LAr and pulse shape discrimination exploiting the characteristic electrical field distribution inside BEGe detectors. The latter technique can identify single-site events (typical for 0νββ) and efficiently reject multi-site events (mainly from γ-rays), as well as different types of background events from detector surfaces. The combined power of these techniques was studied for {sup 42}K and other background sources at the low background facility LArGe. Together with extensive simulations, the information from tracking of the Phase II detector material exposure to cosmic rays and based on the background contributions observed in Phase I, the expected background level in Phase II in the region of interest at 2039 keV, the Q{sub ββ} energy of {sup 76}Ge, is estimated. The preliminary analysis shows that contributions from all expected background components after all cuts are in line with the goal of Gerda Phase II.
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Elamu Silgu tänaval Tallinnas = Dwelling on Silgu Street in Tallinn / Ülar Mark, Indrek Tiigi
Mark, Ülar
2003-01-01
Klaasmaja projekteerija: Arhitektuuribüroo Urban Mark. Arhitektid Ülar Mark ja Indrek Tiigi. Konstruktor: Inseneribüroo Peipman OÜ. Sisekujundaja Raina Lillepõld (OÜ Boxes). Projekt 2002, valmis 2004. 4 välis- ja 3 sisevaadet, põhiplaan
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Tajima, Toshihiro; Tsubaki, Junko; Ishizu, Katsura; Jo, Wakako; Ishi, Nobuaki; Fujieda, Kenji
2008-07-01
The use of octreotide-LAR and cabergoline therapy has shown great promise in adults with acromegaly; however, the experience in pediatric patients has rarely been reported. We described a clinical course of a 15-year-old boy of McCune-Albright syndrome (MAS) with pituitary gigantism. At the age of 8 years, a growth hormone (GH) and prolactin (PRL) producing pituitary adenoma was diagnosed at our hospital. He also had multiple fibrous dysplasia, so that he was diagnosed as having MAS. The tumor was partially resected, and GNAS1 gene mutation (R201C) was identified in affected tissues. We introduced octreotide to suppress GH secretion (100 mug 2/day s.c). During therapy with octreotide, IGF-1 and GH levels could not be suppressed and the patient frequently complained of nausea from octreotide treatment. Therefore, the therapy was changed to monthly injections of octreotide-LAR at the age of 12.3 years and was partially effective. However, as defect of left visual field worsened due to progressive left optic canal stenosis, he underwent second neurological decompression of the left optic nerve at 13.4 years of age. After surgery, in addition to octreotide-LAR, cabergoline (0.25 mg twice a month) was started. This regimen normalized serum levels of GH and IGF-1; however, he showed impaired glucose tolerance and gallstones at 15.7 years of age. Therefore, the dose of octreotide-LAR was reduced to 10 mg and the dose of cabergoline increased. This case demonstrated the difficulty of treating pituitary gigantism due to MAS. The use of octreotide-LAR and cabergoline should be considered even in pediatric patients; however, adverse events due to octreotide-LAR must be carefully examined.
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INSPIRE-00445642; Chen, Kai; Kierstead, James; Lanni, Francesco; Takai, Helio; Jin, Ge
2016-01-01
ATLAS LAr calorimeter will perform its Phase-I upgrade during the long shut down (LS2) in 2018, a new LAr Trigger Digitizer Board (LTDB) will be designed and installed. Several commercial-off-the-shelf (COTS) multichannel high-speed ADCs have been selected as possible backups of the radiation tolerant ADC ASICs for LTDB. In order to evaluate the radiation tolerance of these back up commercial ADCs, we developed an ADC radiation tolerance characterization system, which includes the ADC boards, data acquisition (DAQ) board, signal generator, external power supplies and a host computer. The ADC board is custom designed for different ADCs, which has ADC driver and clock distribution circuits integrated on board. The Xilinx ZC706 FPGA development board is used as DAQ board. The data from ADC are routed to the FPGA through the FMC (FPGA Mezzanine Card) connector, de-serialized and monitored by the FPGA, and then transmitted to the host computer through the Gigabit Ethernet. A software program has been developed wit...
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Lar Betânia: O atendimento à infância abandonada em Maringá – PR
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Ângela Mara de Barros Lara
2012-08-01
Full Text Available O presente artigo discute as políticas públicas de atendimento à criança e ao adolescenteem situação social de risco, na cidade de Maringá-PR, por meio da história do Lar Betânia,um abrigo fundado em 1965, no sistema casa-lar. A instituição que, em muitos períodos desua história chegou a atender, simultaneamente, 100 crianças vive hoje, a possibilidade desucumbir diante da atual filosofia do Estado de priorizar a permanência do menor junto àfamília biológica e, na impossibilidade dessa convivência, encaminhá-lo para acolhimento,junto às famílias cadastradas e preparadas para atuarem como famílias temporárias. Estadiscussão só foi possível a partir do estudo dos pressupostos que evidenciam o papel doEstado e dos direitos sociais na sociedade em que vivemos.
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Aynı coğrafyada iki savaş: Troia ve Çanakkale savaşlarının karşılaştırılması
Körpe, Reyhan
2015-01-01
Yaklaşık üç bin yıl arayla aynı topraklarda meydana gelen iki savaş, Troia ve Çanakkale Savaşları sadece coğrafi benzerlikleri değil, nedenleri, oluş şekli ve sonuçları ile birbirine benzemektedir. Birinci Dünya savaşının bir parçası olan Çanakkale Savaşı gibi, arkeolojik kaynaklar Homeros’un destanlaştırdığı Troia Savaşı’nın Tunç Çağların sonunda Batı Anadolu’daki çok büyük bir mücadelenin parçası olduğunu ortaya koymuştur. Çanakkale Savaşları sırasında kullanılan yöntemlerin antik çağ savaş...
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Directory of Open Access Journals (Sweden)
Jessica Brito Cavalcante
Full Text Available RESUMO: Introdução: O consumo de alimentos fora do lar vem crescendo no Brasil, sendo associado a escolhas alimentares menos nutritivas. Objetivo: Descrever a ingestão de energia e nutrientes específicos entre consumidores e não consumidores de alimentos fora do lar, na Região Nordeste. Métodos: Foram analisados dados do Inquérito Nacional de Alimentação (INA, provenientes da Pesquisa de Orçamentos Familiares (POF 2008-2009, em uma amostra de 11.674 indivíduos residentes na Região Nordeste, que forneceram dois registros alimentares em dias não consecutivos, com informação sobre o local de consumo dos alimentos (dentro ou fora do lar. Alimentação fora do lar foi definida como todo alimento adquirido e consumido fora de casa. Modelos de regressão linear foram desenvolvidos para avaliar a relação entre o consumo alimentar fora do lar em um dos dois dias de registro e a ingestão de energia e nutrientes, ajustados por idade, sexo e renda per capita. Resultados: O consumo de alimentos fora do lar, em pelo menos um dos dois dias de registro alimentar, foi reportado por 42% dos indivíduos. Os indivíduos que consomem alimentos fora do lar apresentaram pior ingestão de nutrientes em comparação com os que não consomem alimentos fora do lar, com maior consumo de energia, açúcar livre, gordura saturada, gordura trans e menor ingestão de proteína, ferro e fibra alimentar, independente da idade, sexo e renda (p < 0,05. Conclusão: A alimentação fora do lar no Nordeste contribuiu para uma maior ingestão de energia e uma pior ingestão de nutrientes. Assim, faz-se necessária a elaboração de políticas públicas e estratégias que favoreçam a escolha de alimentos mais saudáveis quando os indivíduos optam por se alimentar fora do lar.
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Ortaöğretim Öğrencilerinin Yazma Eğilimi Algıları
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Ercan Deniz
2015-04-01
Full Text Available Bu araştırmanın amacı, ortaöğretim öğrencilerinin yazma eğilimi algılarının genel düzeyini tespit ederek yazma eğilimi algısını cinsiyet, sınıf düzeyi, öğrenim alanı, anne eğitim durumu, baba eğitim durumu, kitap okuma sıklığı, facebook ve e-mail kullanma durumlarına göre incelemektir. Araştırma 2013-2014 eğitim-öğretim yılında tesadüfi örnekleme yoluyla seçilen resmi bir okuldaki 317 öğrenci üzerinde yürütülmüştür. Elde edilen veriler SPSS 20.0 paket programı kullanılarak analiz edilmiştir. Verilerin analizinde ilişkisiz örneklem t testi, tek yönlü varyans analizi ve pearson momentler çarpımı korelasyonu kullanılmıştır. Araştırmada elde edilen bulgulara göre ortaöğretim öğrencilerinin yazma eğilimi algılarının “orta düzeyde” olduğu sonucuna ulaşılmıştır. Öğrencilerin yazma eğilimi algılarının cinsiyet, sınıf düzeyi, öğrenim alanı ve kitap okuma sıklığı değişkenlerine göre anlamlı bir farlılık gösterdiği tespit edilmiştir. Anne ve baba eğitim durumuyla facebook ve e-mail kullanma değişkenlerinin yazma eğilimi algısıyla istatiksel olarak anlamlı bir ilişkisi bulunmamaktadır.
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Aynı Coğrafyada İki Savaş: Troia ve Çanakkale Savaşlarının Karşılaştırılması
Reyhan Körpe
2015-01-01
Yaklaşık üç bin yıl arayla aynı topraklarda meydana gelen iki savaş, Troia ve Çanakkale Savaşları sadece coğrafi benzerlikleri değil, nedenleri, oluş şekli ve sonuçları ile birbirine benzemektedir. Birinci Dünya savaşının bir parçası olan Çanakkale Savaşı gibi, arkeolojik kaynaklar Homeros’un destanlaştırdığı Troia Savaşı’nın Tunç Çağların sonunda Batı Anadolu’daki çok büyük bir mücadelenin parçası olduğunu ortaya koymuştur. Çanakkale Savaşları sırasında kullanılan yöntemlerin antik çağ savaş...
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Kobi niteliğindeki sağlık kuruluşlarında iç kontrol sistemi ve önemi
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Güler GÜNEY
2014-06-01
Full Text Available Büyük küçük tüm sağlık kuruluşlarının, sürekliliklerini sağlayabilmeleri ve hedeflerine ulaşabilmeleri bakımından en önemli kriter etkili bir iç kontrol sistemine sahip olmalarıdır. Özellikle Türkiye gibi ekonomisi gelişmekte olan, ticari aktörlerinin çok büyük bir kısmı KOBİ statüsünde olan ülkelerde, ekonomik hayatı hareketlendirmek, sermaye piyasalarının gelişmesi ve işlerliğinin kuvvetlenmesinin sağlanmasında da yine en temel kriter etkin ve etkili bir iç kontrol siteminin varlığıdır. Çünkü etkili bir iç kontrol sistemi; hata, hile ve yolsuzlukların önlenmesinde ve işletme içinde uygulanan politika ve prosedürlerin uygulanma düzeyi ve verimliliğinin sağlanmasında da önemli bir etkendir. İster büyük, ister küçük olsun her işletmede etkin olan ya da olmayan bir iç kontrol mevcuttur. Ancak bu kontrollerin işletmede belirlenmiş bulunan belli politika ve prosedürlere göre yapılıp yapılmadığı ya da etkin olup olmadıkları tartışılabilmektedir. Ülkemizdeki sağlık kuruluşlarından, özellikle sermaye piyasalarında işlem gören kuruluşlarda mevzuatlar gereği iç kontrol sistemi kurulmuş olmasma rağmen, bu iç kontrol sisteminin tamamıyla örgütsel amaçlar doğrultusunda etkili ve verimli şekilde çalıştığını söylemek mümkün değildir. Ülkemizdeki KOBİ niteliğindeki sağlık kuruluşlarının hatırı bir kısmında ise iç kontrol sisteminin oldukça yetersiz ve zayıf olarak nitelenebilecek şekilde uygulandığı ifade edilebilir. Bu da diğer tüm KOBÎ'lerde olduğu gibi sağlık alanındaki kuruluşların büyüme, gelişme ve kurumsallaşması üzerine olumsuz etkide bulunmaktadır. Daha da önemlisi de kurumların örgütsel amaçlarını gerçekleştirmesinde zorluklarla karşılaşmasına sebep olmaktadır. Başka bir deyişle, etkin iç kontrol sisteminin işletmelerin ilgililerine fayda sağlaması gereklidir. Böylece i
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Castillo, Haydee Karina; Caro, Vanesa de los Ángeles; González Blanco, Mireya; Acosta, Ligia; Correnti, María; Suárez, Jony
2015-01-01
Objetivo: Establecer la relación entre el diagnóstico de papilomatosis laríngea juvenil y la infección genital por virus de papiloma humano durante el embarazo. Métodos: Se incluyeron 18 madres de hijos con diagnóstico de papilomatosis laríngea juvenil. Se revisaron las historias de los niños, se realizó anamnesis a las madres buscando antecedentes de infección por virus de papiloma humano durante el embarazo, se practicó evaluación ginecológica actual, citología, vulvoscopia, vaginoscopia, c...
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Gibin, D.
2013-04-01
The proposal for an experimental search for sterile neutrinos beyond the Standard Model with a new CERN-SPS neutrino beam is presented. The experiment is based on two identical LAr-TPC's followed by magnetized spectrometers, observing the electron and muon neutrino events at 1600 and 300 m from the proton target. This project will exploit the ICARUS T600, moved from LNGS to the CERN "Far" position. An additional 1/4 of the T600 detector will be constructed and located in the "Near" position. Two spectrometers will be placed downstream of the two LAr-TPC detectors to greatly complement the physics capabilities. Comparing the two detectors, in absence of oscillations, all cross sections and experimental biases cancel out. Any difference of the event distributions at the locations of the two detectors might be attributed to the possible existence of ν-oscillations, presumably due to additional neutrinos with a mixing angle sin2(2θ) and a larger mass difference Δmnew2. The superior quality of the LAr imaging TPC, in particular its unique electron-π0 discrimination allows full rejection of backgrounds and offers a lossless νe detection capability. The determination of the muon charge with the spectrometers allows the full separation of νμ from anti-νμ and therefore controlling systematics from muon mis-identification largely at high momenta.
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Osmanlı Dönemi Başlıklı Ortakent Mezar Taşları Ottoman Period Headed Gravestones of Ortakent
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H.Kamil BİÇİCİ
2012-12-01
Full Text Available This concerns, “Ortakent Gravestones.”. Among the cemetery of Ortakent, The dates of the gravestones are between 18.th-20.th centuries and 20 samples of 30 are from 18.th. century, 9 are from 19.th., 1 is from 20.th. century. Gravestones were of marble. The lenghts of the stones are between 140 cm.-45 cm., their widths are between 36 cm.-14 cm., their thicknesses are between 14 cm.-3.5 cm. Most of the samples are in rectangular and shapes and some are rectangular-prizmal. 3 of them have Foot gravestones. 30 head gravestones have large wadded turban (kavuk, turban (sarık, fez (fes and kerchief. All of the gravestones have inscriptions. 5 of them are without inscriptions. Inscriptions on 3 samples were laid diagonal, and 27 of them were laid in a linear system, 30 of head ve foot gravesones are in good condition. 3 samples are broken. 19 of 30 gravestones are men’s and 11 are of women’s. While scarping was used for making gravestones are scarping, and painting were used as the maindecoration tecnique is seen on foot stone with the painting technique,inscriptions of stones were coloured. Most of the inscriptions anddecorations are relieved. Decoration subjects seen on gravestones arephytomorphic, geometric, objective and calligraphic. “Osmanlı Dönemi Başlıklı Ortakent Mezar Taşları” konulu bu incelemede Ortakent Mezarlığında bulunan 30 mezar taşı araştırılarak, çalışmamızda yer almıştır. Mezar taşlarında tarihi bilinen bütün örnekler XVII. yy. ikinci çeyreği ile XX. yy. ilk çeyreği arasındadır. 30 örnekten 20 tanesi XVIII. yy., 9 tanesi XIX. yy., 1 tanesi XX. yy.dır. Mezar taşlarının hepsi mermer malzemeden yapılmıştır. Mezar taşlarının büyükten küçüğe doğru boyları 140 cm. ile 45 cm., genişlikleri 36 cm. ile 14 cm., kalınlıkları ise 14 ile 3.5 cm. arasında değişmektedir. Ortakent’te bulunan mezar taşları şahideli tiptedir. Örneklerin çoğu dikdörtgen gövdelidir. 3
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Directory of Open Access Journals (Sweden)
Arun P. Singh
2015-01-01
Full Text Available A study spanning 3.7 years on the butterflies of Gibbon Wildlife Sanctuary GWS (21km2, a semi-evergreen forest, in Jorhat District of Assam, northeastern India revealed 211 species of butterflies belonging to 115 genera including 19 papilionids and seven ‘rare’ and ‘very rare’ species as per Evans list of the Indian sub-continent (Great Blue Mime Papilio paradoxa telearchus; Brown Forest BobScobura woolletti; Snowy Angle Darpa pteria dealbatahas; Constable Dichorragia nesimachus; Grey Baron Euthalia anosia anosia; Sylhet Oakblue Arhopala silhetensis; Branded Yamfly Yasoda tripunctata. The butterflies showed a strong seasonality pattern in this forest with only one significant peak during the post monsoon (September-October when 118 species were in flight inside the forest which slowly declined to 92 species in November-December. Another peak (102 species was visible after winter from March to April. Species composition showed least similarity between pre-monsoon (March-May and post-monsoon (October-November seasons. The number of papilionid species were greater from July to December as compared from January to June. The findings of this study suggest that the pattern of seasonality in a semi-evergreen forest in northeastern India is distinct from that of the sub-tropical lowland forest in the Himalaya. Favourable logistics and rich diversity in GWS points to its rich potential in promoting ‘butterfly inclusive ecotourism’ in this remnant forest.
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Farklı Miktarlarda Üzüm Çekirdeği Tozu İlave Edilmiş Kaplama Harçlarının Reolojik Özellikleri
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Özge Süfer
2015-02-01
Full Text Available Bu çalışmada, üzüm çekirdeği tozu ilavesi yapılmış kaplama harçlarının reolojik özellikleri incelenmiştir. Kaplama harçları; su, buğday unu, mısır unu, tuz, kabartma tozu ve hidroksipropilmetilselülozdan (HPMC oluşan karışıma farklı oranlarda üzüm çekirdeği tozu ilavesi yapılarak üretilmiştir. Örneklerin görünür viskoziteleri sabit sıcaklıkta (15 °C eşmerkezli silindirik tip viskozimetre ile belirlenmiştir. Kaplama harçlarının kıvam katsayıları ve akış davranış indeksleri Üssel Model ile hesaplanmıştır. Bütün örnekler Newton tipi olmayan pseudoplastik tipi akış davranışı sergilemiş ve görünür viskozite değerleri artan kayma hızı ile azalmıştır. Örneklerin görünür viskozite değerleri, artan üzüm çekirdeği konsantrasyonu ile birlikte azalmıştır. Kaplama harçlarının akış davranış indeksi ve kıvam katsayısı değerleri sırasıyla 0.516-0.596 ve 8.994-14.722 Pa.s aralığında bulunmuştur.
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Energy Technology Data Exchange (ETDEWEB)
Hils, Maximilian, E-mail: maximilian.hils@tu-dresden.de
2016-07-11
The ATLAS Liquid Argon (LAr) Calorimeters were designed and built to measure electromagnetic and hadronic energy in proton–proton collisions produced at the Large Hadron Collider (LHC) at centre-of-mass energies up to 14 TeV and instantaneous luminosities up to 10{sup 34} cm{sup −2} s{sup −1}. The High Luminosity LHC (HL-LHC) programme is now developed for up to 5–7 times the design luminosity, with the goal of accumulating an integrated luminosity of 3000 fb{sup −1}. In the HL-LHC phase, the increased radiation levels and an improved ATLAS trigger system require a replacement of the Front-end (FE) and Back-end (BE) electronics of the LAr Calorimeters. Results from research and development of individual components and their radiation qualification as well as the overall system design will be presented.
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Lesiones laríngeas postintubación endotraqueal. Factores de riesgo asociados
Bosque Cebolla, M. Dolores
2015-01-01
Introducción: La intubación endotraqueal para el mantenimiento de una correcta función respiratoria o incluso como mantenimiento de una vía aérea superior permeable es uno de los procedimientos más habituales en los pacientes críticos. Se trata de un procedimiento que no está exento de complicaciones, muchas de ellas relacionadas con la presencia del tubo endotraqueal a nivel laríngeo y que abarcan desde síntomas y lesiones leves y reversibles hasta lesiones más graves como las estenosis lari...
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Chin, Sang Ouk; Chung, Choon Hee; Chung, Yoon-Sok; Kim, Byung-Joon; Kim, Hee Young; Kim, In-Ju; Kim, Jung Guk; Kim, Min-Seon; Kim, Seong-Yeon; Lee, Eun Jig; Lee, Ki Young; Kim, Sung-Woon
2015-01-01
Objectives This study was designed to investigate changes in health-related quality of life (HRQoL) of patients with acromegaly in Korea after medical treatment with octreotide LAR using the validated Korean version of the acromegaly quality of life questionnaire (AcroQoL). Design A prospective, open-label, single-arm study. Setting 11 tertiary centres in Korea. Participants 58 Korean patients (aged 21–72 years) who were newly diagnosed with acromegaly between 2009 and 2012 were prescribed octreotide LAR 20 mg at the time of enrolment. During 24 weeks of observation, AcroQoL survey questionnaires and measurement of growth hormone insulin-like growth factor 1(GH/IGF-I) were performed at baseline, week 12 and week 24. Main outcome measures We assessed the HRQoL of Korean patients with acromegaly after medical treatment with octreotide LAR using the validated Korean version of the AcroQoL questionnaire. Results Patients had a mean age of 47.2 years (29 males), and GH and IGF-I significantly decreased during the first 12 weeks (GH: 4.8 vs 1.9 μg/L, pacromegaly has a limited contribution to HRQoL as assessed by the AcroQoL. PMID:26063564
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Et Ürünlerinde Bitkisel Yağların Kullanımı
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Gülen Yıldız Turp
2015-02-01
Full Text Available Yağ tüketimi ile çeşitli hastalıklar arasındaki ilişki, tüketicileri diyetlerindeki yağın miktarı ve özellikleriyle daha fazla ilgili olmaya yöneltmektedir. İşlenmiş et ürünlerinin yağ oranları daha az yağlı etlerin kullanımını içeren formülasyonlarla azaltılabilmekte, ancak bu girişim ekonomik olmadığı gibi ürün kalitesinde de istenmeyen değişikliklere yol açabilmektedir. Kolesterol içermeyen ve doymamış yağ asitlerini yüksek oranlarda içeren bitkisel yağların et ürünlerinde kullanımı ile daha sağlıklı et ürünleri üretimi mümkün görünmektedir. Bu çalışmada çeşitli et ürünlerinde bitkisel yağların kullanımının, ürün özellikleri üzerine etkileri literatüre dayanılarak incelenmiştir.
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Quinney, A.; Murray, M. S.; Gobroski, K. A.; Topp, R. M.; Pfirman, S. L.
2015-12-01
The resurgence of audio programming with the advent of podcasting in the early 2000s spawned a new medium for communicating advances in science, research, and technology. To capitalize on this informal educational outlet, the Arctic Institute of North America partnered with the International Arctic Research Center, the University of Alaska Fairbanks, and the UA Museum of the North to develop a podcast series called PoLAR Voices for the Polar Learning and Responding (PoLAR) Climate Change Education Partnership. PoLAR Voices is a public education initiative that uses creative storytelling and novel narrative structures to immerse the listener in an auditory depiction of climate change. The programs will feature the science and story of climate change, approaching topics from both the points of view of researchers and Arctic indigenous peoples. This approach will engage the listener in the holistic story of climate change, addressing both scientific and personal perspectives, resulting in a program that is at once educational, entertaining and accessible. Feedback is being collected at each stage of development to ensure the content and format of the program satisfies listener interests and preferences. Once complete, the series will be released on thepolarhub.org and on iTunes. Additionally, blanket distribution of the programs will be accomplished via radio broadcast in urban, rural and remote areas, and in multiple languages to increase distribution and enhance accessibility.
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Energy Technology Data Exchange (ETDEWEB)
Gibin, D., E-mail: daniele.gibin@pd.infn.it
2013-04-15
The proposal for an experimental search for sterile neutrinos beyond the Standard Model with a new CERN-SPS neutrino beam is presented. The experiment is based on two identical LAr-TPC's followed by magnetized spectrometers, observing the electron and muon neutrino events at 1600 and 300 m from the proton target. This project will exploit the ICARUS T600, moved from LNGS to the CERN “Far” position. An additional 1/4 of the T600 detector will be constructed and located in the “Near” position. Two spectrometers will be placed downstream of the two LAr-TPC detectors to greatly complement the physics capabilities. Comparing the two detectors, in absence of oscillations, all cross sections and experimental biases cancel out. Any difference of the event distributions at the locations of the two detectors might be attributed to the possible existence of ν-oscillations, presumably due to additional neutrinos with a mixing angle sin{sup 2}(2θ{sub new}) and a larger mass difference Δm{sub new}{sup 2}. The superior quality of the LAr imaging TPC, in particular its unique electron-π{sub 0} discrimination allows full rejection of backgrounds and offers a lossless ν{sub e} detection capability. The determination of the muon charge with the spectrometers allows the full separation of ν{sub μ} from anti-ν{sub μ} and therefore controlling systematics from muon mis-identification largely at high momenta.
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ATLAS LAr Calorimeter Trigger Electronics Phase-1 Upgrade
Aad, Georges; The ATLAS collaboration
2017-01-01
The upgrade of the Large Hadron Collider (LHC) scheduled for a shut-down period of 2019-2020, referred to as the Phase-I upgrade, will increase the instantaneous luminosity to about three times the design value. Since the current ATLAS trigger system does not allow sufficient increase of the trigger rate, an improvement of the trigger system is required. The Liquid Argon (LAr) Calorimeter read-out will therefore be modified to use digital trigger signals with a higher spatial granularity in order to improve the identification efficiencies of electrons, photons, tau, jets and missing energy, at high background rejection rates at the Level-1 trigger. The new trigger signals will be arranged in 34000 so-called Super Cells which achieves 5-10 times better granularity than the trigger towers currently used and allows an improved background rejection. The readout of the trigger signals will process the signal of the Super Cells at every LHC bunch-crossing at 12-bit precision and a frequency of 40 MHz. The data will...
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Brecht e Lars Von Trier: Hibridismo e anti-ilusionismo em Dogville (2003
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Otávio Cabral
2014-12-01
Full Text Available A proposta do presente artigo é refletir acerca da herança brechtiana no cinema contemporâneo, atravésda análise do filme Dogville (2003, do cineasta dinamarquês Lars Von Trier. Dogville (2003, inseridonos postulados do movimento cinematográfico Dogma 95, é um exemplo de hibridez artística ou um“cinema de fusão”, como prefere o diretor. O cinema de Von Trier nega Hollywood, assim como o teatrode Brecht nega a catarse aristotélica, marcando-se, decididamente, como propostas que têm em comum,entre outras características, a anti-ilusão.
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DEFF Research Database (Denmark)
hart, Leen M; Hansen, Torben; Rietveld, Ingrid
2005-01-01
Previously, we have shown that a mutation in the mitochondrial DNA-encoded tRNA(Leu(UUR)) gene is associated with type 2 diabetes. One of the consequences of this mutation is a reduced aminoacylation of tRNA(Leu(UUR)). In this study, we have examined whether variants in the leucyl tRNA synthetase...... gene (LARS2), involved in aminoacylation of tRNA(Leu(UUR)), associate with type 2 diabetes. Direct sequencing of LARS2 cDNA from 25 type 2 diabetic subjects revealed eight single nucleotide polymorphisms. Two of the variants were examined in 7,836 subjects from four independent populations...... in the Netherlands and Denmark. A -109 g/a variant was not associated with type 2 diabetes. Allele frequencies for the other variant, H324Q, were 3.5% in type 2 diabetic and 2.7% in control subjects, respectively. The common odds ratio across all four studies was 1.40 (95% CI 1.12-1.76), P = 0.004. There were...
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İlköğretim Öğretmen Adaylarının Sera Etkisi İle İlgili Kavram Yanılgıları
Arsal, Zeki
2010-01-01
Bu çalışmanın amacı ilköğretim fen bilgisi ve sınıf öğretmenliği kavram yanılgılarını döndürmek. Araştırma eğitim fakültesi ilköğretim fen bilgisi ve sınıf öğretmenliği bölümler öğrenim gören 171 öğretmen adayı ile yapılmış. Çalışmada sera etkisinin nedenleri, sonuçları ve sera açısından önleme yollarıyla ilgili kavram yanılgıları araştırılmıştır. Araştırmanın anlamı toplanması "Sera Etkisi le lgili Düşünceler Anketi" Anket üç alt boyuttan ve yirmi üç maddeden. Deneme hakkı hem fen ...
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Üstün Zekâlılar: Özellikleri, Tanılanmaları, Eğitimleri (KİTAP İNCELEMELERİ
Directory of Open Access Journals (Sweden)
Şule Demirel
2013-06-01
Full Text Available “Üstün Zekâlılar: Özellikleri, Tanılanmaları, Eğitimleri” adlı yenilenmiş ikinci basım olan bu kitap; üstün zekâ tanımları ve tarihçesi, üstün zekâ kuramları, üstün zekâlıların özellikleri ve gelişimleri, tanılama, eğitim stratejileri, müfredat tasarımı ve müfredat modelleri, eğitim prog-ramı tasarımı, program değerlendirmesi, sosyal-duyuşsal-akademik konular ve rehberlik, üs-tün zekâlı öğrencilerin öğretmenleri olmak üzere on bölümden oluşmaktadır.
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Operation of a LAr-TPC equipped with a multilayer LEM charge readout
Baibussinov, B.; Centro, S.; Farnese, C.; Fava, A.; Gibin, D.; Guglielmi, A.; Meng, G.; Pietropaolo, F.; Varanini, F.; Ventura, S.; Zatrimaylov, K.
2018-03-01
A novel detector for ionization signals in a single phase LAr-TPC has been experimented in the ICARINO test facility at the INFN Laboratories in Legnaro. It is based on the adoption of a multilayer Large Electron Multiplier (LEM) replacing the traditional anodic wire arrays. Cosmic muon tracks were detected allowing the measurement of energy deposition and a first determination of the signal to noise ratio. The analysis of the recorded events demonstrated the 3D reconstruction capability of this device for ionizing events in liquid Argon. The collected fraction of ionization charge is close to about 90%, with signal to noise ratio similar to that measured with more traditional wire chambers.
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ATLAS LAr Calorimeter Performance in LHC Run-2
Yatsenko, Elena; The ATLAS collaboration
2017-01-01
The ATLAS detector was designed and built to study proton-proton collisions produced at the LHC at centre-of-mass energies up to 14 TeV and instantaneous luminosities up to 1034 cm−2 s−1. Liquid argon (LAr) sampling calorimeters are employed for all electromagnetic calorimetry in the pseudo-rapidity region |η| < 3.2, and for hadronic calorimetry in the region from |η| = 1.5 to |η| = 4.9. In the first LHC run a total luminosity of 27 fb−1 has been collected at center-of-mass energies of 7-8 TeV between year of 2010 to 2012. Following a period of detector consolidation during a long shutdown, Run-2 started with approximately 3.9 fb-1 and 35.6 fb-1 of data at a center-of-mass energy of 13 TeV recorded in 2015 and 2016, respectively. In order to realize the level-1 acceptance rate of 100 kHz in Run-2 data taking, number of read-out samples for the energy and the time measurement has been modified from five to four with keeping the expected performance. The well calibrated and highly granular Liquid Ar...
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Stereotipik Davranışların Azaltılmasında Kullanılan Yöntemlerin Etkililiği: Betimsel ve Meta Analizi
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Özlem Toper Korkmaz
2010-07-01
Full Text Available Yineleyici, tekrarlanan davranış olarak tanımlanan stereotipi, farklı gelişimsel yetersizlik türlerinde görülmekle beraber, yaygın olarak otistik bozukluk (otizm gösteren bireylerde de gözlenmekte ve otistik bozukluğun ayırıcı tanı ölçütlerinden birini oluşturmaktadır. Geçmişten günümüze çeşitli yöntemlerin stereotipik davranışların azaltılmasında kullanıldığı görülmektedir. Bu çalışmada da stereotipik davranışların azaltılmasında kullanılan yöntemlerin etkililiklerini incelemek amaçlanmıştır. Bu amaçla 1996 ile 2010 yılları arasında tarama yapılarak otistik bozukluk gösteren bireylerde vokal ya da motor stereotipi veya her ikisinin birden azaltılmasının amaçlandığı toplam 18 araştırma betimsel ve meta analizi yapılarak incelenmiştir. Araştırmanın betimsel analiz sonuçları stereotipik davranışların azaltılmasında kullanılan yöntemlerin etkili olduğunu gösterirken, meta analizi sonuçları yöntemlerin “şüpheli” olduğu sonucunu göstermiştir. Stereotypic behavior is defined repetitive behaviors observed various types of developmental disorders, especially in autism and is also a discriminative criterion to diagnose the autism. Various procedures have been used to reduce the stereotypic behaviors in individuals with these behaviors. The purpose of this study is to investigate the procedures’ effectiveness about reducing the stereotypic behaviors. A total of 18 studies were examined published in between 1996 and 2010 about reducing vocal stereotypy, motor stereotypy or both of them. Descriptive and meta-analysis were carried out on these studies. Whereas results of descriptive analysis revealed that the examined procedures are effective to reduce the stereotypic behaviors, results of meta-analysis showed that these procedures are “uncertain”.
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Ege Bölgesi Zeytinyağlarının Fenolik Bileşenleri
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Hasan Hüseyin Kara
2018-02-01
Full Text Available Bu çalışmada, Türkiye’de başlıca zeytin yetiştiriciliği yapan Ege bölgesinin bazı illerinden (Muğla, Aydın, İzmir ve Manisa 2 hasat dönemi (2007-2008 ve 2008-2009 süresince yerli zeytin çeşitlerinin (Gemlik, Memecik, Ayvalık, Uslu ve Domat yağı incelenmiştir. Bu yağların toplam fenolik madde ve fenolik bileşimi belirlenmiştir. Yağların toplam fenolik madde içeriği, 2007-2008 hasat dönemi örneklerinde 23,69-153,64 mg kafeik asit/kg, 2008-2009 hasat dönemi örneklerinde 16,18-136,22 mg kafeik asit/kg aralığında belirlenmiştir. Tüm zeytinyağı örneklerinde tespit edilen fenolik maddeler; tirozol, oleuropein, 4-hidroksifenil asetik asit, luteolin, vanilik asit, hidroksitirozol, rutin, sinnamik asit, verbaskozit, hidroksi fenilkarboksilik asit, sirinjik asit, 3,4-dihidroksibenzoik asit, kafeik asit, ferulik asit, p-kumarik asit, taksifolin ve apigenindir. Tirozol ve oleuropeinin, 2007-2008 hasat döneminde 1,80-13,39 mg/kg, 1,26-19,50 mg/kg ve 2008-2009 hasat döneminde ise 1,76-11,66 mg/kg, 0,20-13,12 mg/kg aralığında en fazla miktarda değişen bileşenler olduğu saptanmıştır.
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Priegnitz, Mike; Thaler, Jan; Spangenberg, Erik; Schicks, Judith M.; Abendroth, Sven
2014-05-01
The German gas hydrate project SUGAR studies innovative methods and approaches to be applied in the production of methane from hydrate-bearing reservoirs. To enable laboratory studies in pilot scale, a large reservoir simulator (LARS) was realized allowing for the formation and dissociation of gas hydrates under simulated in-situ conditions. LARS is equipped with a series of sensors. This includes a cylindrical electrical resistance tomography (ERT) array composed of 25 electrode rings featuring 15 electrodes each. The high-resolution ERT array is used to monitor the spatial distribution of the electrical resistivity during hydrate formation and dissociation experiments over time. As the present phases of poorly conducting sediment, well conducting pore fluid, non-conducting hydrates, and isolating free gas cover a wide range of electrical properties, ERT measurements enable us to monitor the spatial distribution of these phases during the experiments. In order to investigate the hydrate dissociation and the resulting fluid flow, we simulated a hydrate production test in LARS that was based on the Mallik gas hydrate production test (see abstract Heeschen et al., this volume). At first, a hydrate phase was produced from methane saturated saline water. During the two months of gas hydrate production we measured the electrical properties within the sediment sample every four hours. These data were used to establish a routine estimating both the local degrees of hydrate saturation and the resulting local permeabilities in the sediment's pore space from the measured resistivity data. The final gas hydrate saturation filled 89.5% of the total pore space. During hydrate dissociation, ERT data do not allow for a quantitative determination of free gas and remaining gas hydrates since both phases are electrically isolating. However, changes are resolved in the spatial distribution of the conducting liquid and the isolating phase with gas being the only mobile isolating phase
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Bağlamsal Değerlendirme Envanteri: Otizmli Bireylerin Problem Davranışlarının Bağlamsal Değişkenleri
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Bülbin Sucuoğlu
2017-07-01
Full Text Available Bu çalışmada otizm spektrum bozukluğu olan bireylerin problem davranışlarına yol açan öncüller, çevresel olaylar ve bağlamları belirlemek amacıyla Bağlamsal Değerlendirme Envanteri’nin Türkçe Formu (BDE-T ile yaşları 15-37 arasında olan 23 otizmli bireyin problem davranışlarına ilişkin veri toplanmış ve bireylerin problem davranışlarına yol açan bağlamsal değişkenler araştırılmıştır. Öncelikle psikometrik özellikleri incelenen BDE-T daha sonra farklı kurumlara devam eden otizmli bireylerle çalışan 20 öğretmen tarafından doldurulmuş, envanterde yer alan maddelerin ortalama puanları ve yüzdeleri hesaplanmış, açık uçlu sorulara verilen yanıtlar analiz edilerek otizmli bireylerin problem davranışlarına en fazla yol açan bağlamsal değişkenler belirlenmiştir. Otizmli bireylerin problem davranışlarına en fazla sosyo-kültürel değişkenler (çalışanın ses tonu, çalışanın düşüncelerini olumsuz şekilde ifade etmesi, bireyin isteklerinin karşılanmaması, ödül ya da pekiştireç almaması, vb. ile görev ya da etkinliğin özelliklerinin (zor görevler, sıkıcı görevler, bireyin çok hata yapması, rutinlerdeki değişiklikler, vb. yol açtığı bulunmuştur. Araştırmacılar BDE-T’nin otizmli bireylerin problem davranışlarına yol açan bağlamları belirlemede güvenilir bir araç olduğunu bildirerek, BDE-T’nin bir problem davranışın bağlamını belirlemek ve bu davranışı önlemeyi hedefleyen bir müdahale programı planlamak amacıyla öğretmenler ve özel eğitimciler tarafından kullanabileceğini açıklamışlardır. In this study, to identify the antecedents, environmental events, and contexts which evoke problem behaviors of individuals with autism spectrum disorder (ASD, data was collected by the Turkish Form of the Contextual Assessment Inventory (CAI-T from 23 individuals who were 15-37 years old and the contextual variables which evoke
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Directory of Open Access Journals (Sweden)
H.Kâmil BİÇİCİ
2012-09-01
gravestones in the Museum of lamps and candelabra motifs is important. İznik ilçesinin güzel tarihi binalarından biri olan müze, Nilüfer Hatun İmareti denilen bir yapıdır. İmaret, Osmanlı hükümdarı Orhan Gazi'nin karısı Nülüfer Hatun tarafından 1388 yılında yapılmıştır. Yapı, kubbe ve tonozların örttüğü sütun ve payelerin taşıyıcı oldukları bir revakla başlamaktadır. Üzerinde kitabe bulunan bir kapı ile ana bölüme girilmektedir. Ana bölüm, merkezi bir kubbe ile örtülüdür. Ana bölümden üzerleri birer kubbeyle örtülü yan mekânlara geçilmektedir. Müze koleksiyonunu yeni keşfedilen bazı Selçuklu, Osmanlı çinileri ve mezar taşları ile Roma kalıntıları ve cam eserler oluşturmaktadır. İznik Müzesindeki mezar taşlarından 11 tanesinde kandil, 5 tanesinde şamdan motifi bulunmaktadır. Örneklerin 9 tanesinde kitabe yer almaktadır. Taşlardan biri sağlam durumda iken, diğerleri eksik, kırık ve aşınmış durumdadır. Malzeme olarak bütün mezar taşlarında mermer kullanılmıştır. Kandil motiflerinin çoğu çift zincirli ve çift kulplu verilmiştir. Kitabeli olan mezar taşlarının hepsinin ön üst yüzüne bitkisel unsurlar, rumi, palmet motifleri yerleştirilmiştir. Mezar taşlarının boyu 125 cm. ile 46 cm., eni 54 cm. ile 26 cm., kalınlığı 15 cm. ile 6 cm. arasında değişmektedir. Şahidelerin hepsi oyma tekniğiyle yapılmıştır. Süsleme tekniği olarak oyma ve kazıma tekniği de 13 mezar taşında uygulanmıştır. Kitabelerin ve bezemelerin çoğu kabartma görünümünde ele alınmıştır. İncelediğimiz mezar taşları örnekleri bitkisel, geometrik, nesneli ve yazı bezemelidir. 13 mezar taşı bitkisel bezemeli, 9 tanesi yazı bezemeli, 7tanesi geometrik bezemeli, 14 tanesi ise nesneli bezemelidir. Bitkisel bezemeler; kır çiçeği, kıvrık dal, palmet, palmiye, rozet, rumi, yaprak şekillerinde olup, taşlar üzerinde az sayıda ele alınmışlardır. Geometrik bezemeler
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Huynh, Lynn; Totev, Todor; Vekeman, Francis; Neary, Maureen P; Duh, Mei S; Benson, Al B
2017-09-01
To calculate the cost reduction associated with diarrhea/flushing symptom resolution/improvement following treatment with above-standard dose octreotide-LAR from the commercial payor's perspective. Diarrhea and flushing are two major carcinoid syndrome symptoms of neuroendocrine tumor (NET). Previously, a study of NET patients from three US tertiary oncology centers (NET 3-Center Study) demonstrated that dose escalation of octreotide LAR to above-standard dose resolved/improved diarrhea/flushing in 79% of the patients within 1 year. Time course of diarrhea/flushing symptom data were collected from the NET 3-Center Study. Daily healthcare costs were calculated from a commercial claims database analysis. For the patient cohort experiencing any diarrhea/flushing symptom resolution/improvement, their observation period was divided into days of symptom resolution/improvement or no improvement, which were then multiplied by the respective daily healthcare cost and summed over 1 year to yield the blended mean annual cost per patient. For patients who experienced no diarrhea/flushing symptom improvement, mean annual daily healthcare cost of diarrhea/flushing over a 1-year period was calculated. The economic model found that 108 NET patients who experienced diarrhea/flushing symptom resolution/improvement within 1 year had statistically significantly lower mean annual healthcare cost/patient than patients with no symptom improvement, by $14,766 (p = .03). For the sub-set of 85 patients experiencing resolution/improvement of diarrhea, their cost reduction was more pronounced, at $18,740 (p = .01), statistically significantly lower than those with no improvement; outpatient costs accounted for 56% of the cost reduction (p = .02); inpatient costs, emergency department costs, and pharmacy costs accounted for the remaining 44%. The economic model relied on two different sources of data, with some heterogeneity in the prior treatment and disease status of patients
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Directory of Open Access Journals (Sweden)
Hugo Eckener Dantas de Pereira Cardoso
2007-08-01
Full Text Available JUSTIFICATIVA E OBJETIVOS: A máscara laríngea tem sido utilizada com freqüência em Anestesiologia. O emprego dessa técnica, embora esteja relacionado com um menor número de complicações quando comparado com a cânula traqueal, não é isento de morbidade, principalmente, nos casos de via aérea difícil. O objetivo desse relato foi apresentar um caso de lesão unilateral de nervo lingual após o uso da máscara laríngea. RELATO DO CASO: Paciente do sexo feminino foi submetida à intervenção cirúrgica para troca de prótese mamária bilateral, sob anestesia geral balanceada, com máscara laríngea de tamanho 3. O volume aplicado para insuflação do balonete foi de 30 mL de ar. Após a primeira hora do pós-operatório, iniciou quadro de dormência e dor na garganta e nos dois terços posteriores da língua que evoluiu em 24 horas com perda da percepção do sabor dos alimentos. A suspeita diagnóstica foi de neuropraxia do nervo lingual pelo uso de máscara laríngea. Esse quadro se manteve por três semanas, período em que se obteve resolução dos sintomas. CONCLUSÃO: Complicações após o uso de máscara laríngea, apesar de raras, podem ocorrer. A neuropraxia do nervo lingual é uma delas. O seu diagnóstico é clínico, e a sua evolução, favorável, com resolução dos sintomas em semanas ou meses.JUSTIFICATIVA Y OBJETIVOS: La máscara laríngea ha sido utilizada con frecuencia en Anestesiología. El empleo de esa técnica, aunque esté relacionada a un menor número de complicaciones cuando se le compara a la cánula traqueal, no está exento de morbidez, principalmente en los casos de vía aérea difícil. El objetivo de este relato fue presentar un caso de lesión unilateral de nervio lingual trás del uso de la máscara laríngea. RELATO DEL CASO: Paciente del sexo femenino, sometida a intervención quirúrgica para cambio de prótesis mamaria bilateral, bajo anestesia general balanceada, con máscara laríngea de tama
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Directory of Open Access Journals (Sweden)
Selma Alves Rodrigues Montefusco
2011-06-01
Full Text Available Este estudo objetivou identificar o diagnóstico de enfermagem “manutenção do lar prejudicada” em familiares, na situação de acompanhantes de pacientes hospitalizados com doenças crônicas não transmissíveis. Foi realizada pesquisa descritiva, de janeiro a junho de 2006, em hospital de grande porte da Região Centro-Oeste, envolvendo 12 famílias. A manutenção do lar prejudicada, identificada em 08 famílias, teve como fatores relacionados mais frequentes: doença de membro da família (100%; organização do lar insuficiente (75%; finanças insuficientes (62,5%. Características definidoras de maior ocorrência foram: membros da família expressam dificuldade para manter a sua casa de forma confortável (62,5%; membros da família pedem ajuda para a manutenção da casa (62,5% e membro da família sobrecarregado (filha, 62,5%. Este diagnóstico afeta as famílias, evidenciando a necessidade dos enfermeiros utilizarem conhecimentos e tecnologias de avaliação e intervenção em famílias, juntamente com linguagens padronizadas para expressar seus diagnósticos, intervenções e resultados alcançados.
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Lar mountain phosphate ore processing using flotation approach
International Nuclear Information System (INIS)
Gharabaghi, M.; Noaparast, M.; Shafaei Tonkaboni, S. Z.
2007-01-01
The sample of Lar Mountain Phosphate deposit which is located in the southwest of Iran, was studied to upgrade its phosphate grade. The results obtained from mineralogical studies showed the presence of apatite, CaO, Al 2 O 3 , Fe 2 O 3 and SiO 2 , in which carbonate was detected as the main gangue. Two sets of direct and reverse flotation tests were performed using samples from this deposit with 10% P 2 O 5 . In phosphate flotation (direct approach), the samples were conditioned with sodium silica, oleic acid-fuel oil and Armac T-fuel oil. The direct flotation at pH=9.2 yielded a product with 23.2% of P 2 O 5 and 75.16% recovery. The reverse flotation tests were carried out at pH=5.2, with floating carbonate and pulp de-oiling, using H 2 SO 4 and wash water, and phosphate was then floated from siliceous gangue. In the second sets of the reverse approach, depressing the phosphate and floating silica with Amines in natural pH were done. However the best concentrate assay was 31.2% P 2 O 5 with a 71.12% recovery, which was obtained from reverse tests
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ATLAS LAr Calorimeters Performance in LHC Run-2
Camincher, Clement; The ATLAS collaboration
2018-01-01
The ATLAS detector was designed and built to study proton-proton collisions produced at the LHC at centre-of-mass energies up to 14 TeV and instantaneous luminosities above 1034 cm−2 s−1. Liquid argon (LAr) sampling calorimeters are employed for all electromagnetic calorimetry in the pseudo-rapidity region |η| < 3.2, and for hadronic and forward calorimetry in the region from |η| = 1.5 to |η| = 4.9. In the first LHC run a total luminosity of 27 fb−1 has been collected at center-of-mass energies of 7-8 TeV between year of 2010 to 2012. After a period of detector consolidation during a long shutdown, Run-2 started in 2015 and 3.9 fb-1, 35.6 fb-1 and 46.9 fb-1 of data at a center-of-mass energy of 13 TeV have been recorded up to now per year. In order to realize the level-1 acceptance rate of 100 kHz in Run-2 data taking, the number of read-out samples recorded and used for the energy and the time measurement has been modified from five to four while keeping the expected performance. The well calibra...
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İşitme Kayıplı Çocuğu Olan Bir Annenin Etkileşim Davranışlarının Aile Eğitimi Bağlamında İncelenmesi
Directory of Open Access Journals (Sweden)
Emel Ertürk Mustul
2016-04-01
Full Text Available Bu eylem araştırmasında çok ileri dereceli işitme kayıplı çocuğu olan işiten bir annenin etkileşim davranışları ve bu davranışlarının desteklenme biçiminin aile eğitimi bağlamında incelenmesi amaçlanmıştır. Araştırmanın verileri aile eğitimi video kayıtları, anneyle yapılan görüşmeler, yazarlar arasında yapılan aile eğitimi değerlendirmeleri ile geçerlik güvenirlik toplantılarında alınan ses kayıtları, aile eğitimi seans planları ve araştırmacı günlükleriyle toplanmıştır. Toplam sekiz aile eğitimi yapılmıştır ve annenin etkileşim davranışlarını incelemek amacıyla ikinci, dördüncü, altıncı ve sekizinci aile eğitimlerinde yer alan on dakikalık anne-çocuk etkileşimi bölümleri temsili video kaydı olarak belirlenmiş ve tümevarım analizi uygulanmıştır. Analiz sonucunda beş etkileşim davranışı belirlenmiĢ ve bu davranışlar iki tema altında toplanmıştır. Annenin etkileşim davranışları bu davranış tanımları altında incelenmiş, davranışların görülme sıklığına bakılmış ve bu davranışları desteklemeye dair eylem planları geliştirilmiştir. Araştırmanın bulguları annenin etkileşimi destekleyen davranışlarının arttığını, etkileşimi olumsuz etkileyen davranışlarının da azaldığını göstermiştir. Araştırma sonuçlarını genellemek mümkün olmasa da elde edilen bulguların etkileşime odaklanan aile eğitimi programının bu anne-çocuk çifti için işlediğini ve erken çocukluk dönemi boyunca aile eğitiminin devam etmesi gerektiğini gösterdiği ileri sürülebilir. The main purpose of this action research was to examine the interactive behaviour of a mother who has a child with a hearing loss and the way these skills were supported in the context of parent guidance process. The data were collected by the video recordings of the parent guidance sessions, audio recordings of session evaluation meetings among
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La relación euro-dólar: seis años después que el euro presentase su mínimo nivel
Directory of Open Access Journals (Sweden)
John Jairo García Rendón
2007-10-01
Full Text Available Este artículo muestra la relación del tipo de cambio euro-dólar desde que el euro empezó a circular. Específicamente, después de considerar algunos elementos teóricos que determinan el tipo de cambio, explica los principales hechos que llevaron a que el euro a partir de octubre de 2000 revertiera su tendencia decreciente frente al dólar y qué aspectos están influyendo en la actualidad sobre su desempeño, llegando a la conclusión que no es posible establecer un modelo que pondere las variables de forma racional y significativa, haciendo que el comportamiento del tipo de cambio no pueda ser explicado en su totalidad por la teoría económica existente.
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Manejo integral de la deglución en el paciente oncológico laríngeo
Ibeas Encinas, Federico
2015-01-01
Introducción: El cáncer de laringe es una de las neoplasias de cabeza y cuello más frecuentes. Aunque la verdadera incidencia de los trastornos de la deglución en este tipo de pacientes no puede ser conocida, es visible que este problema es muy amplio y sus consecuencias pueden ser muy severas. Para un adecuado tratamiento de los trastornos deglutorios provocados por la cirugía laríngea conservadora, a menudo coadyuvada con radioterapia y quimioterapia, es necesario un abordaje...
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ATLAS LAr calorimeter performance and LHC Run-2 commissioning
AUTHOR|(INSPIRE)INSPIRE-00366625; The ATLAS collaboration
2016-01-01
The ATLAS detector was built to study proton-proton collisions produced by the Large Hadron Collider (LHC) at a center of mass energy of up to 14 TeV. The Liquid Argon (LAr) calorimeters are used for all electromagnetic calorimetry as well as the hadronic calorimetry in the endcap and forward regions. They have shown excellent performance during the first LHC data taking campaign, from 2010 to 2012, so-called Run 1, at a peak luminosity of $8 \\times 10^{33} \\text{cm}^{-2}\\text{s}^{-1}$. During the next run, peak luminosities of $1.5 \\times 10^{34} \\text{cm}^{-2}\\text{s}^{-1}$ and even higher are expected at a 25ns bunch spacing. Such a high collision rate may have an impact on the quality of the energy reconstruction which is attempted to be maintained at a high level using a calibration procedure described in this contribution. It also poses major challenges to the first level of the trigger system which is constrained to a maximal rate of 100 kHz. For Run-3, scheduled to start in 2019, instantaneous luminos...
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Geynisman, M; Chalifour, M; Delaney, M; Dinnon, M; Doubnik, R; Hentschel, S; Kim, M J; Montanari, C; Montanari, D; Nichols, T; Norris, B; Sarychev, M; Schwartz, F; Tillman, J; Zuckerbrot, M
2017-01-01
The Short-Baseline Neutrino (SBN) physics program at Fermilab and Neutrino Platform (NP) at CERN are part of the international Neutrino Program leading to the development of Long-Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) science project. The SBN program consisting of three Liquid Argon Time Projection Chamber (LAr-TPC) detectors positioned along the Booster Neutrino Beam (BNB) at Fermilab includes an existing detector known as MicroBooNE (170-ton LAr-TPC) plus two new experiments known as SBN’s Near Detector (SBND, ~260 tons) and SBN’s Far Detector (SBN-FD, ~760 tons). All three detectors have distinctly different design of their cryostats thus defining specific requirements for the cryogenic systems. Fermilab has already built two new facilities to house SBND and SBN-FD detectors. The cryogenic systems for these detectors are in various stages of design and construction with CERN and Fermilab being responsible for delivery of specific sub-systems. This contribution prese...
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Directory of Open Access Journals (Sweden)
Hasan Çoruk
2017-04-01
Full Text Available This study aimed to investigate the effect of multimedia material covering 4th grade mathematics course fractions topic on students’ academic achievement levels, math anxiety, computer anxiety levels and thoughts on multimedia. A quasi-experimental design with pre-test - post-test and control group was conducted. The study was carried out with 31 students in each group: 13 male and 18 female students in the experimental group and 12 male and 19 female students in the control group. “Fractions Achievement Test”, “Mathematics Anxiety Scale”, “Computer Anxiety Scale”, and “Interview Form” were used as data collection tools. It was concluded that multimedia applications were more effective than traditional teaching methods in terms of improving academic achievement. According to the math anxiety data, neither multimedia applications nor traditional teaching methods were effective in relieving math anxiety of the students. The anxiety existing before the study was significantly reduced. The analysis of the interview forms indicated that multimedia applications helped students in some areas such as effective presentation, revising the subjects, increasing the interest in the course and providing a fun study environment. Multimedia applications were recommended to be used effectively in other courses as well in terms of lesson presentation, course revision and educational games. [Bu çalışmanın amacı 4. sınıf matematik dersi kesirler konusunda hazırlanan çoklu ortamların öğrencilerin akademik başarı düzeylerine, matematik kaygı düzeylerine, bilgisayar kaygı düzeylerine ve çoklu ortamlar hakkında düşüncelerine etkisini araştırmaktır. Araştırmada ön test - son test kontrol gruplu yarı deneysel desen kullanılmıştır. Deney grubunda 13 erkek ve 18 kız, kontrol grubunda da 12 erkek ve 19 kız olmak üzere 31’er öğrenci ile çalışma tamamlanmıştır. Veri toplama araçları olarak “Kesirler Konusu
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İstanbul Kıyı Balıkçılığında Kullanılan Dip Uzatma Ağlarının Teknik Özellikleri.
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Taner Yıldız
2015-12-01
Full Text Available Bu çalışmayla, İstanbul kıyı balıkçılığında kullanılan dip uzatma ağlarının teknik özellikleri tespit edilmiştir. Bölgede altı adedi fanyalı ve yedi adedi sade olmak üzere toplam 13 tip dip uzatma ağı tanımlanmıştır. Bu uzatma ağlarının teknik planları FAO standartlarına göre ilk defa tanıtılmıştır
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Ectocranial suture fusion in primates: pattern and phylogeny.
Cray, James; Cooper, Gregory M; Mooney, Mark P; Siegel, Michael I
2014-03-01
Patterns of ectocranial suture fusion among Primates are subject to species-specific variation. In this study, we used Guttman Scaling to compare modal progression of ectocranial suture fusion among Hominidae (Homo, Pan, Gorilla, and Pongo), Hylobates, and Cercopithecidae (Macaca and Papio) groups. Our hypothesis is that suture fusion patterns should reflect their evolutionary relationship. For the lateral-anterior suture sites there appear to be three major patterns of fusion, one shared by Homo-Pan-Gorilla, anterior to posterior; one shared by Pongo and Hylobates, superior to inferior; and one shared by Cercopithecidae, posterior to anterior. For the vault suture pattern, the Hominidae groups reflect the known phylogeny. The data for Hylobates and Cercopithecidae groups is less clear. The vault suture site termination pattern of Papio is similar to that reported for Gorilla and Pongo. Thus, it may be that some suture sites are under larger genetic influence for patterns of fusion, while others are influenced by environmental/biomechanic influences. Copyright © 2013 Wiley Periodicals, Inc.
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Solvents orgànics en electroforesi capil·lar i cromatografia de líquids
Subirats i Vila, Xavier
2007-01-01
La cromatografia de líquids d'alta eficàcia (HPLC) és la tècnica de separació més àmpliament utilitzada, degut a la seva sensibilitat, exactitud de les determinacions quantitatives i aplicabilitat a anàlits no volàtils o termolàbils d'interès científic i industrial. L'electroforesi capil·lar juga un paper fonamental en bioquímica. Aquesta tècnica permet obtenir anàlisis ràpides amb una elevada resolució i un baix consum de reactius auxiliars, fet que minimitza la generació de residus. L'objec...
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Maria Cecília Barreto Amorim Pilla
2008-06-01
Full Text Available A partir do conceito de auto-governo, entendido como um modelo psicológico capaz de garantir o reconhecimento e respeito do próximo, uma valorização de si mesmo, este artigo propõe uma reflexão a respeito da mulher no desempenho do papel de "rainha do lar" no Brasil do início do século XX. Na preparação da casa repousava a valorização de uma conduta controlada da dona-de-casa, que deveria manter o controle sobre tudo e sobre todos, tendo aí a oportunidade de demonstrar sua capacidade de governar a si, seu lar e sua família.This study begins from the concept of self-guidance understood as a psychological model capable to guarantee the recognition and respect of the next one, a self-valorization. It propitiates a reflection regarding the woman in the performance of the paper of "queen of the home" in Brazil of the beginning of the XX century. In the preparation of the house rested the valuation of a controlled behavior of the housewife, that would have to keep the control on everything and all, having there the chance to demonstrate its capacity to govern itself, its home and its family.
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Energy Technology Data Exchange (ETDEWEB)
Geynisman, M. [Fermilab; Bremer, J. [CERN; Chalifour, M. [CERN; Delaney, M. [Fermilab; Dinnon, M. [Fermilab; Doubnik, R. [Fermilab; Hentschel, S. [Fermilab; Kim, M. J. [Fermilab; Montanari, C. [INFN, Pavia; Monatanari, D. [Fermilab; Nichols, T. [Fermilab; Norris, B. [Fermilab; Sarychev, M. [Fermilab; Schwartz, F. [Fermilab; Tillman, J. [Fermilab; Zuckerbrot, M. [Fermilab
2017-08-31
The Short-Baseline Neutrino (SBN) physics program at Fermilab and Neutrino Platform (NP) at CERN are part of the international Neutrino Program leading to the development of Long-Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) science project. The SBN program consisting of three Liquid Argon Time Projection Chamber (LAr-TPC) detectors positioned along the Booster Neutrino Beam (BNB) at Fermilab includes an existing detector known as MicroBooNE (170-ton LAr-TPC) plus two new experiments known as SBN’s Near Detector (SBND, ~260 tons) and SBN’s Far Detector (SBN-FD, ~760 tons). All three detectors have distinctly different design of their cryostats thus defining specific requirements for the cryogenic systems. Fermilab has already built two new facilities to house SBND and SBN-FD detectors. The cryogenic systems for these detectors are in various stages of design and construction with CERN and Fermilab being responsible for delivery of specific sub-systems. This contribution presents specific design requirements and typical implementation solutions for each sub-system of the SBND and SBN-FD cryogenic systems.
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Directory of Open Access Journals (Sweden)
Seda Özkandan
2015-02-01
Full Text Available Bu çalışmada, tek üzüm çeşidinden (Misket, yaş üzümden ve kuru üzüm suması melas alkolü karışımından üretilen farklı tipteki rakıların bileşimleri ve temel uçucu bileşikleri araştırılmıştır. Metanol ve temel uçucu bileşikler (asetaldehit, asetal, metil asetat, etil asetat, 2-bütanol, n-propanol, izobütanol, n-bütanol, aktif amil alkol, izoamil alkol, trans anetol ve estragol AB referans yöntemine göre GC- FID ile belirlenmiştir. Rakıların temel uçucu bileşiklerini, sırasıyla, anason kaynaklı trans anetol ve suma kaynaklı yüksek alkoller, esterler, aldehitler ve uçucu asitler oluşturmuştur. Rakılarda, toplam uçucu madde miktarları uçar asit dahil, 124.99-163.40 g/hL mA arasında, trans anetol miktarları 1038-1380 mg/L arasında, metanol miktarları 43.96-56.91 g/hL mA arasında değişmiştir. En yüksek toplam uçucu madde miktarı Misket üzümünden elde edilen rakıda bulunmuştur. Tek çeşitten ve yaş üzümden üretilen rakıların, karışımdan üretilen rakılara göre daha yüksek miktarlarda toplam uçucu madde ve özellikle yüksek alkoller içerdikleri belirlenmiştir. Yüksek alkol miktarları bakımından tipler arasındaki fark önemli bulunmuştur (P<0.05. Trans anetol miktarı en yüksek yaş üzüm rakısında, en düşük misket rakısında belirlenmiştir. Öte yandan, genel olarak rakıların bileşimlerinin TGK Distile Alkollü İçkiler Tebliği’ne uygun oldukları saptanmıştır.
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Amanda Magri Eller
2016-06-01
Full Text Available Purpose: Understand the tactics that nontraditional students use to manage the boundaries between work, home and study. Originality/gap/relevance/implications: The originality of this study relies on transfer of the focus from the conflict to the balance between work, home and study. It also breaks new ground by directing attention to the micro level of individual action, in contrast to a literature that traditionally studied organizational actions. Finally, it performs an innovative reading of the interface between work, home and study domains from the perspective of the boundary theory. Key methodological aspects: This qualitative study was held from 18 interviews that were recorded, transcribed and content analyzed, which revealed a list of individual tactics employed by respondents to reconcile the demands of work, home and study. Summary of key results: The analysis allowed us to identify 18 tactics that our respondents employ to negotiate the level of permeability between the boundaries between work, school and home. These tactics were classified as behavioral, communicative, physical and temporal. Key considerations/conclusions: The study revealed that students develop an active role by interpreting the expectations of the social actors from the home and work domains and from the institution where they study and adopt boundaries with degrees of permeability that enable a state of greater balance between these domains Objetivo: Compreender as táticas que estudantes não tradicionais utilizam para gerenciar as fronteiras entre trabalho, lar e estudo. Originalidade/Lacuna/Relevância/Implicações: O estudo se mostra original ao transferir o foco do conflito para o equilíbrio entre trabalho, lar e estudos. Além disso, também inova ao direcionar a atenção para o nível micro da ação individual, contrastando com uma literatura que tradicionalmente estuda ações organizacionais. Por fim, realiza uma leitura inovadora do fenômeno da
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Cynthia Priscila Ferreira
2009-01-01
Full Text Available OBJETIVO: Descrever os sintomas e sinais vocais e laríngeos de pacientes com diagnóstico de bulimia. MÉTODOS: Estudo transversal, descritivo, randomizado, com experimento cego. Avaliou-se 11 indivíduos com diagnóstico de bulimia, com o subtipo purgativo, do sexo feminino e idade variando de 18 a 34 anos, que foram submetidas à avaliação fonoaudiológica e otorrinolaringológica. RESULTADOS: Os sintomas laríngeos e vocais mais relatados foram: o pigarro e a sensação de globus faríngeo relatados por dez sujeitos (90,9%. Na avaliação perceptivo-auditiva, os escores de maior ocorrência foram de grau leve em todos os parâmetros analisados. Os achados laríngeos de maior ocorrência foram os acúmulos de secreção espessa na laringe em cinco paciente (45,4%, seguido de fenda triangular médio-posterior e espessamento de mucosa na região interaritenoidea, ambos, ocorrendo em quatro sujeitos (36,3%. CONCLUSÃO: Os achados laringológicos e perceptivo-auditivos foram menos expressivos que os sintomas vocais e laríngeos relatados pelas pacientes.PURPOSE: To describe vocal and laryngeal signs and symptoms in patients with bulimia. METHODS: A blind, descriptive, randomized, transversal study was carried out. Eleven female subjects with the diagnosis of purgative bulimia nervosa and ages ranging from 18 to 34 years underwent otorhinolaryngological and vocal evaluations. RESULTS: The most common vocal and laryngeal symptoms were throat clearing and globus faringeus, related by 10 subjects (90.9%. In the auditory-perceptive evaluation, the most common scores were characterized as light in all analyzed parameters. The accumulation of thick mucus over the larynx occurred in five patients (45.4%, followed by median-posterior triangular glottic chink and mucosal thickening at the interaytenoid region, in four patients (36.3%. CONCLUSION: The laryngeal and perceptual findings were less expressive than vocal and laryngeal complaints.
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Karasu (Sakarya Bölgesi Deniz Balıkçılarının Sosyo-Ekonomik Yapısı.
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Selçuk Uzmanoğlu
2015-12-01
Full Text Available Bu çalışmada, Sakarya ili Karasu ilçesi deniz balıkçılarının sosyo-ekonomik yapısı incelenmiştir. Bu amaçla hazırlanan anket formları Temmuz 2004-Temmuz 2005 tarihleri arasında toplam dört kez bölgeye gidilerek uygulanmıştır. Karasu ilçesinde, deniz balıkçılığı yapan, Sakarya Tarım İl Müdürlüğü’ne kayıtlı 143 adet balıkçı teknesi mevcuttur. 36 balıkçı teknesi trol ve gırgır, 107 tekne ise 11.00 m den ufak diğer sınıfına ait ruhsata sahiptir. Balıkçıların yaş dağılımları, eğitim durumları, medeni durumları, eşlerinin eğitim ve iş durumu, çocukların eğitim durumları, avlanmanın hangi dönemlerde yapıldığı, toplam av günü sayısı, av sahasının limana olan uzaklığı, avlanan su ürünleri türleri, balıkçı teknelerinin özellikleri ve kullanılan av araçları incelenmiştir. Balıkçı teknelerinin boyu maksimum 22.00 m ve minimum 6.50 m, tekne yaşı maksimum 45 yıl ve minimum 2 yıl, avlanma süresi maksimum 240 gün ve minimum 30 gün olduğu; palamut, lüfer, barbunya, tekir, mezgit, istavrit, kalkan, kefal, tirsi, köpek balığı, vatoz, kum midyesi ve deniz salyangozunun ağırlıklı olarak avlandığı belirlenmiştir
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Search for space charge effects in the ICARUS T600 LAr-TPC
Torti, Marta
2016-11-01
Space charge in Liquid Argon Time Projection Chamber is due to the accumu- lation of positive ions, produced by ionizing tracks crossing the detector, which slowly flow toward the cathode. As a consequence, electric field distortions may arise, thus hindering the possibility to produce faithful 3D images of the ionizing events. The presence of space charge becomes relevant for large TPCs operating at surface or at shallow depths, where cosmic ray flux is high. These effects could interest the next phase of the ICARUS T600 detector, which will be deployed at shallow depths as a Far Detector for Short Baseline Neutrino experiment at FNAL dedicated to sterile neutrino searches. In 2001, the first ICARUS T600 module (T300) operated at surface in Pavia (Italy), recording cosmic ray data. In this work, a sample of cosmic muon tracks from the 2001 run was analyzed and results on space charge effects in LAr-TPCs are shown.
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Search for space charge effects in the ICARUS T600 LAr-TPC
International Nuclear Information System (INIS)
Torti, Marta
2016-01-01
Space charge in Liquid Argon Time Projection Chamber is due to the accumu- lation of positive ions, produced by ionizing tracks crossing the detector, which slowly flow toward the cathode. As a consequence, electric field distortions may arise, thus hindering the possibility to produce faithful 3D images of the ionizing events. The presence of space charge becomes relevant for large TPCs operating at surface or at shallow depths, where cosmic ray flux is high. These effects could interest the next phase of the ICARUS T600 detector, which will be deployed at shallow depths as a Far Detector for Short Baseline Neutrino experiment at FNAL dedicated to sterile neutrino searches. In 2001, the first ICARUS T600 module (T300) operated at surface in Pavia (Italy), recording cosmic ray data. In this work, a sample of cosmic muon tracks from the 2001 run was analyzed and results on space charge effects in LAr-TPCs are shown
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Yerel E-Katılımın Yeni Aracı Olarak Sosyal Ağlar: Facebook ve Twitter Örneği
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Levent MEMİŞ
2015-04-01
Full Text Available Bu araştırmada, son yıllarda örgütleri ve bireylerin iletişim veya etkileşim sürecine yeni bir hız kazandıran sosyal ağların, daha da özelde Facebook ve Twitter araçlarının, belediye örgütleri ve belediye başkanları düzeyinde, yerel kamusal politikalara katılım bağlamında, “ne düzeyde” ve “nasıl” kullanıldığının ortaya çıkarılmasına çalışılmıştır. Bu kapsamda, kişisel düzeyde 6 belediye başkanının Facebook ve 12 belediye başkanının Twitter; kurumsal düzeyde ise 22 belediyenin Facebook ve yine 22 belediyenin Twitter hesabı araştırma kapsamında niteliksel içerik analizi yöntemiyle incelenmiştir. Çalışmanın genel sonuçlarına göre, kişisel Twitter hesaplarında sorunları ileten/bilgi talep eden etkileşim öne çıkmakla birlikte, hesaplardaki üye sayısı dikkate alındığında sınırlı düzeyde etkileşimin olduğu, daha çok katılımın ilk evresi olarak kabul edilen bilgi aktaran, doğrudan katılımı teşvik etmeyen biçiminde kullanıldığı tespit edilmiştir.
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Eiden Maribeth V
2011-07-01
Full Text Available Abstract Background Over the last several decades it has been noted, using a variety of different methods, that cells infected by a specific gammaretrovirus are resistant to infection by other retroviruses that employ the same receptor; a phenomenon termed receptor interference. Receptor masking is thought to provide an earlier means of blocking superinfection, whereas receptor down regulation is generally considered to occur in chronically infected cells. Results We used replication-competent GFP-expressing viruses containing either an amphotropic murine leukemia virus (A-MLV or the gibbon ape leukemia virus (GALV envelope. We also constructed similar viruses containing fluorescence-labeled Gag proteins for the detection of viral particles. Using this repertoire of reagents together with a wide range of antibodies, we were able to determine the presence and availability of viral receptors, and detect viral envelope proteins and particles presence on the cell surface of chronically infected cells. Conclusions A-MLV or GALV receptors remain on the surface of chronically infected cells and are detectable by respective antibodies, indicating that these receptors are not downregulated in these infected cells as previously proposed. We were also able to detect viral envelope proteins on the infected cell surface and infected cells are unable to bind soluble A-MLV or GALV envelopes indicating that receptor binding sites are masked by endogenously expressed A-MLV or GALV viral envelope. However, receptor masking does not completely prevent A-MLV or GALV superinfection.
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Liliana Marcela Bastos Osorio
2013-03-01
Full Text Available En este artículo se presentan los resultados de una investigación, de un proyecto de grado de la maestría en Gerencia de Empresas de la Universidad Experimental del Táchira (Venezuela, cuyo objetivo general fue determinar la relación de la paridad cambiaria dólar/peso en la liquidez y rentabilidad de las MIPYMES del sector de las confecciones en la ciudad de Cúcuta (2005-2008. Esta investigación fue de carácter descriptivo y correlacional, teniendo en cuenta datos contables, financieros y teorías financieras, las cuales permitieron determinar indicadores financieros que arrojaron los siguientes resultados: se presenta un proceso de revaluación del peso colombiano frente al dólar; se observa una aparente liquidez sustentada en altos inventarios; y la rentabilidad del sector es variable en los años de estudio y con tendencia a la disminución. Según la regresión lineal, aplicada entre estas variables, el comportamiento de la tasa de cambio del dólar solo afecta por el lado de la liquidez al indicador de la productividad del capital de trabajo; mientras que por el lado de la rentabilidad existen dos indicadores que presentan un alto grado de correlación con la tasa promedio del dólar. Para ello, se propone dos pasos para la ayuda al sector: una primera etapa es la realización de un diagnóstico del mismo sector que contemple aspectos mesoeconómicos y financieros; y una segunda etapa es la creación de una asociación gremial de las MiPyMEs del sector de confecciones de Cúcuta.
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Cold front-end electronics and Ethernet-based DAQ systems for large LAr TPC readout
D.Autiero,; B.Carlus,; Y.Declais,; S.Gardien,; C.Girerd,; J.Marteau; H.Mathez
2010-01-01
Large LAr TPCs are among the most powerful detectors to address open problems in particle and astro-particle physics, such as CP violation in leptonic sector, neutrino properties and their astrophysical implications, proton decay search etc. The scale of such detectors implies severe constraints on their readout and DAQ system. We are carrying on a R&D in electronics on a complete readout chain including an ASIC located close to the collecting planes in the argon gas phase and a DAQ system based on smart Ethernet sensors implemented in a µTCA standard. The choice of the latter standard is motivated by the similarity in the constraints with those existing in Network Telecommunication Industry. We also developed a synchronization scheme developed from the IEEE1588 standard integrated by the use of the recovered clock from the Gigabit link
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Sinéad Lyons
Full Text Available Hepatitis B virus (HBV infections are widely distributed in humans, infecting approximately one third of the world's population. HBV variants have also been detected and genetically characterised from Old World apes; Gorilla gorilla (gorilla, Pan troglodytes (chimpanzee, Pongo pygmaeus (orang-utan, Nomascus nastusus and Hylobates pileatus (gibbons and from the New World monkey, Lagothrix lagotricha (woolly monkey. To investigate species-specificity and potential for cross species transmission of HBV between sympatric species of apes (such as gorillas and chimpanzees in Central Africa or between humans and chimpanzees or gorillas, variants of HBV infecting captive wild-born non-human primates were genetically characterised. 9 of 62 chimpanzees (11.3% and two from 11 gorillas (18% were HBV-infected (15% combined frequency, while other Old world monkey species were negative. Complete genome sequences were obtained from six of the infected chimpanzee and both gorillas; those from P. t .ellioti grouped with previously characterised variants from this subspecies. However, variants recovered from P. t. troglodytes HBV variants also grouped within this clade, indicative of transmission between sub-species, forming a paraphyletic clade. The two gorilla viruses were phylogenetically distinct from chimpanzee and human variants although one showed evidence for a recombination event with a P.t.e.-derived HBV variant in the partial X and core gene region. Both of these observations provide evidence for circulation of HBV between different species and sub-species of non-human primates, a conclusion that differs from the hypothesis if of strict host specificity of HBV genotypes.
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Iyat Sudrajat
2017-05-01
Full Text Available Development of Ecotourism Program at Mandalawangi Resort of Mount Gede Pangrango National Park (TNGGP is done by optimizing the supply of tourist collaborated with tourist demand. Tourism resource most interesting at Resort Mandalawangi namely Puncak Gunung Gede - Pangrango then others are rare animals such as Leopards java (Panthera pardus is the key species and Javan Gibbon (Hylobates Molloch as a flagship species, as well as waterfalls, crater, Blue Lake, and Gayonggong Swamp. Social and cultural potential of a pattern of community life Sundanese-oriented agriculture as well as the existence of the mythical legend of the kingdom in TNGGP. Visitors dominant male, student status with the last education of SMP / MTs, 16-20-year-old, from Bekasi to have the motivation tends to settle for pleasure. Assess visitors tend not to know that TNGGP have ecotourism program that School Visit, Visit to School, Conservation Camp, Local Content Filling Material Environmental Education / Nature Conservation and Environmental Education for Teachers, Farmers, and the Young Generation. The concept of program development of ecotourism in Resort Mandalawangi using the theme "TNGGP, Cultured Conservation Area". This concept will focus on the utilization of resources and nature taking into consideration the safety of visitors as well as integrate with shades of Sundanese culture around tourism area Cibodas. Another aspect that needs to be developed to support the promotion of ecotourism programs, establish Sundanese cultural nuances and supporting infrastructure at KWC, strengthening human resources ecotourism program managers. Keywords: development, ecotourism, potential, program, TNGGP
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R&D Studies of the ATLAS LAr Calorimeter Readout Electronics for super-LHC
Chen, H
2009-01-01
The ATLAS Liquid Argon (LAr) calorimeters are high precision, high sensitivity and high granularity detectors designed to provide precision measurements of electrons, photons, jets and missing transverse energy. 180,000 signals are digitized and processed real-time on detector, to provide energy and time deposited in each detector element at every occurrence of the L1-trigger. A luminosity upgrade (x10) of the LHC will occur around 2016. The current readout electronics will have to be upgraded to sustain the higher radiation levels. A completely innovative readout scheme is being developed. The frontend readout will send out data continuously at each bunch crossing through highspeed radiation resistant optical links. The data (100Gbps each board) will be processed real-time with the possibility of implementing trigger algorithms for clusters and electron/photon identification at a much higher granularity than what currently implemented. We present here an overview of the R&D activities and architectural s...
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Upgraded readout electronics for the ATLAS LAr Calorimeter at the High Luminosity LHC
Andeen, T; The ATLAS collaboration
2012-01-01
The ATLAS Liquid Argon (LAr) calorimeters produce a total of 182,486 signals which are digitized and processed by the front-end and back-end electronics at every triggered event. In addition, the front-end electronics is summing analog signals to provide coarsely grained energy sums, called trigger towers, to the first-level trigger system, which is optimized for nominal LHC luminosities. However, the pile-up noise expected during the High Luminosity phases of LHC will be increased by factors of 3 to 7. An improved spatial granularity of the trigger primitives is therefore proposed in order to improve the identification performance for trigger signatures, like electrons or photons, at high background ejection rates. For the first upgrade phase [1] in 2018, new digital tower builder boards (sTBB) are being designed to receive higher granularity signals, digitize them on detector and send them via fast optical links to a new digital processing system (DPS). The DPS applies a digital filtering and identifies sig...
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Directory of Open Access Journals (Sweden)
A. V. Dreval’
2014-01-01
Full Text Available Background: Somatostatin analogues therapy is an important part of the acromegalic patients’ treatment. Aim: Assessment of treatment efficiency for patients with acromegaly using different doses of somatostatin analogues. Materials and methods: The data of 128 acromegaly patients registered in Moscow Region were analyzed, 79 (61.7% of them were treated with somatostatin analogues. The treatment was started with a dose of 20 mg. If the target levels of growth hormone (GH and type 1 insulin-like growth factor (IGF-1 were not achieved within 6-12 months, the dose was increased to 30 mg, and then to 40 mg. If GH and IGF-1 levels fell under the target values, the dose was decreased to 10 mg. The rate of achievement of optimal GH and IGF-1 levels was analyzed depending on the somatostatin analogue doses used. Results: The percentage of the acromegalic patients who were under the first and the second lines of drug therapy, was almost similar: 55.7 and 44.3%, respectively. Sandostatin LAR in dose of 10 mg was given to 4 (5.1% of 79 patients, 20 mg – to 33 (41.8%, 30 mg – to 11 (13.9%, and 40 mg – to 31 (39.2% patients. The target levels of GH and IGF-1 were achieved in 57.6, 54.5, and 32.2% of patients, who received preparation in doses 20, 30, and 40 mg, respectively. Achievement of, at least, one planned criterium (GH or IGF-1 was additionally noted in 10 of 33 (30.3%, 4 of 11 (36.2%, and 9 of 31 (29% patients within these study groups. The rate of side effects didn’t increase with the raising of оctreotide dose. Conclusion: Application of long-acting release octreotide (Sandostatin-LAR in doses of 30 and 40 mg is safe and allows to increase percentage of acromegalic patients who achieve a biochemical control over acromegaly.
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Abendroth, Sven; Thaler, Jan; Klump, Jens; Schicks, Judith; Uddin, Mafiz
2014-05-01
In the context of the German joint project SUGAR (Submarine Gas Hydrate Reservoirs: exploration, extraction and transport) we conducted a series of experiments in the LArge Reservoir Simulator (LARS) at the German Research Centre of Geosciences Potsdam. These experiments allow us to investigate the formation and dissociation of hydrates at large scale laboratory conditions. We performed an experiment similar to the field-test conditions of the production test in the Mallik gas hydrate field (Mallik 2L-38) in the Beaufort Mackenzie Delta of the Canadian Arctic. The aim of this experiment was to study the transport behavior of fluids in gas hydrate reservoirs during depressurization (see also Heeschen et al. and Priegnitz et al., this volume). The experimental results from LARS are used to provide details about processes inside the pressure vessel, to validate the models through history matching, and to feed back into the design of future experiments. In experiments in LARS the amount of methane produced from gas hydrates was much lower than expected. Previously published models predict a methane production rate higher than the one observed in experiments and field studies (Uddin et al. 2010; Wright et al. 2011). The authors of the aforementioned studies point out that the current modeling approach overestimates the gas production rate when modeling gas production by depressurization. They suggest that trapping of gas bubbles inside the porous medium is responsible for the reduced gas production rate. They point out that this behavior of multi-phase flow is not well explained by a "residual oil" model, but rather resembles a "foamy oil" model. Our study applies Uddin's (2010) "foamy oil" model and combines it with history matches of our experiments in LARS. Our results indicate a better agreement between experimental and model results when using the "foamy oil" model instead of conventional models of gas flow in water. References Uddin M., Wright J.F. and Coombe D
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Aslı ALBAYRAK
2013-07-01
şağı turistlerin tatil yerlerine karar vermeleri üzerine destinasyon imajını oluşturan faktörlerin etkisini saptamak ve Y kuşağı turistlerin yapısal özellikleri ile destinasyon algıları arasındaki ilişkiyi inceleyerek söz konusu kuşak için destinasyon pazarlamasına ilişkin önerilerde bulunmak amacıyla yapılmıştır.Çalışmada nicel araştırma yöntemlerinden anket tekniğinden yararlanılmış, İstanbul’da bu kuşağı temsil eden ve kota örnekleme yöntemiyle belirlenen 384 kişiyle yüz yüze anket çalışması yapılmıştır. Elde elde verilerin analizinde betimsel istatistik, t-testi ve Anova Analizi kullanılmıştır.Araştırmanın sonuçlarına göre destinasyon imajı katılımcıların cinsiyetlerine, eğitim durumlarına ayrıca gelir düzeylerine göre farklılık göstermektedir. Diğer yandan, Y Kuşağı turistlerinin dinlenme, eğlenme ve yeni yerler görme isteği ile hareket ettikleri, kalite ve lüks bir tatili uygun fiyata arayan bireylerden oluştuğu söylenebilir.Turistik satın alma süreci birçok faktörün etkisiyle şekillenmektedir. Bu süreci etkileyen faktörlerden birisi de destinasyon imajıdır. En genel tanımıyla destinasyon imajı bireylerin bir yer hakkındaki genel algılarıdır ve bu algılar yaş, eğitim, gelir, kültür gibi bir çok faktörden etkilenmektedir. Geçmişte turistlerin destinasyon tercihleri ile ilgili çeşitli çalışmalar yapılmış ve bu çalışmalarda genel olarak turistlerin yaş, eğitim, kültür, gelir gibi özelliklerinin destinasyon imaj algıları üzerine etkileri incelenmiştir ancak farklı kuşakların destinasyon imaj algıları ile ilgili herhangi bir çalışmaya rastlanmamıştır. Bu nedenle bu çalışma sonucunda elde edilen sonuçların turizm pazarlamacılarına katkı sağlayabileceği düşünülmüştür.
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Diagnóstico patológico y molecular de un caso de tuberculosis laríngea primaria en un médico
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Leonardo F. Jurado
2014-03-01
Full Text Available La tuberculosis laríngea primaria es una enfermedad rara con una amplia gama de manifestaciones clínicas. Se reporta el caso de un médico otorrinolaringólogo con diabetes de tipo II y con diagnóstico de tuberculosis laríngea primaria. El diagnóstico de cáncer de cuerda vocal se había considerado en otra institución, y al ingreso el paciente sólo presentaba disfonía de seis meses de evolución. En el estudio histopatológico se encontraron granulomas, células gigantes multinucleadas, fibrosis y necrosis, y en la tinción de Ziehl-Neelsen, bacilos ácido-alcohol resistentes. El cultivo del tejido de cuerda vocal para micobacterias y la PCR-IS6110 fueron positivos. La cepa de Mycobacterium tuberculosis demostró sensibilidad a todos los medicamentos de primera línea. Se inició tratamiento según la estrategia DOTS (Directly Observed Treatment, Short-course. Se discute la presentación clínica, los diagnósticos diferenciales, el abordaje diagnóstico y los factores de riesgo asociados y se hace una breve revisión de la literatura.
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Sahra SAYGAN
2013-09-01
Full Text Available Whistleblowing can be defined as revealing non-ethical events or behaviors (likeproducing harmful foods even though marketing them as they are remedial in anorganization. Organizational Ethical Climate is the second concept used in this work. Itconsists of workers’ opinions about the ethical organizational culture of management. Inthis work the relationship between “whistleblowing” and “ethical climate” is searched.The questionnaire used to evaluate the relationship between whistleblowing and ethicalclimate are applied on 123 research assistants in public universities. In the applicationstudy it’s reached that there is not a significant relationship between whistleblowing andethical climate. Even though it’s found that there is not a significant relationship between“whistleblowing” and “ethical climate”; a small significant relationship is discoveredbetween “whistleblowing” and “benevolent ethical climate”.Ahlaki olmayan davranışların duyurulması (Whistleblowing, bir işletmedeki etikolmayan davranış ve olayların açığa çıkarılması olarak tanımlanabilir. Etik iklim iseçalışanların örgüt kültürünün etiksel boyutuyla ilgili gözlem ve görüşlerindenoluşmaktadır. Bu çalışma, ‘Ahlaki olmayan davranışların duyurulması’ ve ‘Etik iklim’arasında anlamlı bir ilişkinin mevcut olup olmadığını araştırmaktadır. ‘Ahlaki olmayandavranışların duyurulması’ ve ‘Etik iklim’ arasındaki ilişkiyi ölçmek için kullanılan anketçalışması devlet üniversitelerindeki 123 araştırma görevlisi üzerinde uygulanmıştır.Uygulama çalışması neticesinde “Ahlaki olmayan davranışların duyurulması” ile “Etikİklim” arasında anlamlı bir ilişkinin bulunmamasına rağmen; etik iklim boyutlarından biriolan “Yardımsever Etik İklim” ile “Ahlaki olmayan davranışların duyurulması” arasındaanlamlı bir ilişkinin mevcut olduğu sonucuna ulaşılmıştır.
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SEZGİN, Ferudun; DURAN, Erol
2014-01-01
Bu çalışmanın amacı, ilköğretim okulu öğretmenlerinin istenmeyen öğrenci davranışlarıyla karşılaşma ve bu davranışlara yönelik önleyici stratejiler ile müdahale yöntemlerini kullanma düzeylerini araştırmaktır. Tarama modelinde tasarlanan bu araştırmaya Ankara\\'daki ilköğretim okullarında görevli toplam 249 öğretmen katılmıştır. Öğretmenlerin istenmeyen öğrenci davranışlarıyla karşılaşma ve bu davranışlara yönelik müdahale yöntemlerini kullanma düzeylerinde cinsiyet, branş ve eğitim düzey...
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Development of new readout electronics for the ATLAS LAr calorimeter at the sLHC
Strässner, A
2009-01-01
The ATLAS Liquid Argon (LAr) calorimeter consists of 182,486 detector cells whose signals need to be read out, digitized and processed, in order to provide signal timing and the energy deposited in each detector element. The current readout electronics is not designed to sustain the ten times higher radiation levels expected at sLHC in the years beyond 2017, and will be replaced by new electronics with a completely different readout scheme. The future on-detector electronics is planned to send out all data continuously at each bunch crossing, as opposed to the current system which only transfers data at a trigger-accept signal. Multiple high-speed and radiation-resistant optical links will transmit 100 Gbps per front-end board, each covering 128 readout channels. The off-detector processing units will not only process the data in real-time and provide digital data buffering, but will also implement trigger algorithms. An overview about the various components necessary to develop such a complex system will be ...
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Pizza ve Milföy Hamurlarının Özgül Isılarının Belirlenmesi
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Seher Kumcuoğlu
2015-02-01
Full Text Available Bu çalışmada milföy ve pizza hamurlarının özgül ısıları fark tarama kalorimetresi (DSC kullanılarak -60 °C ile 100 °C sıcaklık aralığında deneysel olarak belirlenmiştir. Örneklerin donmuş durumdaki özgül ısı değerlerinin donmamış durumuna ait özgül ısı değerlerinden daha düşük olduğu ve sıcaklığın artmasıyla arttığı bulunmuştur. Donmamış durumda ise örneklerin özgül ısı değerlerinin sıcaklıkla artış gösterdiği saptanmıştır. Milföy hamurunun özgül ısı değerinin donmuş ve donmamış durumda pizza hamurunun özgül ısı değerinden daha düşük olduğu saptanmıştır. Ölçüm sonuçlarının literatürde bulunan değerlerle uyumlu olduğu görülmüştür.
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Hélio A. G. Teive
2001-03-01
Full Text Available A distonia laríngea (disfonia espasmódica é distúrbio do movimento caracterizado por contrações involuntárias da musculatura laríngea envolvida no processo de vocalização. A utilização da toxina botulínica no tratamento da distonia laríngea trouxe consideráveis benefícios clínicos. Descrevemos os resultados preliminares do uso terapêutico da toxina botulínica no tratamento da distonia laríngea em 12 pacientes. Após investigação clínica, os pacientes foram submetidos a videolaringoestroboscopia para confirmação diagnóstica e as injeções de toxina botulínica foram realizadas através de punção da membrana cricotireóidea em direção ao músculo tireoaritenóideo, com uso de eletromiografia. A maioria dos pacientes submetidos ao tratamento com toxina botulínica apresentou melhora significativa da distonia laríngea (83% dos casos, com duração média do efeito de quatro meses, sem efeitos colaterais significativos.Laryngeal dystonia (spasmodic dysphonia is a movement disorder characterized by involuntary contractions of laryngeal muscles involved with vocalization. The introduction of botulinum toxin in the treatment of laryngeal dystonia had a major clinical impact due to the striking improvement of symptoms. We report the preliminary results of therapeutical use of botulinum toxin in the treatment of twelve patients with laryngeal dystonia. After an extensive clinical evaluation, the patients underwent a videostroboscopic exam for diagnostic confirmation. Botulinum toxin was injected in the cricothyreoid membrane, directed towards the thyreoaritenoid muscle, with the aid of eletromyography needles. Most of patients who underwent botulinum toxin injection had a significant improvement of their symptoms (83%, with effects lasting for four months in average and without important side effects.
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International Nuclear Information System (INIS)
Ajaltouni, Z.; Boldea, V.; Constantinescu, S.; Dita, S.; Pantea, V.
1999-01-01
The future ATLAS experiment at the CERN Large Hadron Collider (LHC) will include in the central ('barrel') region a calorimeter system composed of two separate units: a liquid argon (LAr) electromagnetic calorimeter and a scintillating-tile hadronic calorimeter. This system must be capable of identifying electrons, photons, and jets and of reconstructing their energies and angles, as well as of measuring missing transverse energy in the event. Over the past few years, several prototypes of the two calorimeters went through a series of separate tests, carried out at CERN SPS in beams of pions, muons and electrons at several values for incident momenta in the range 10 - 300 GeV/c. The barrel calorimeters were tested as well in a combined mode. An azimuthal sector of the ATLAS barrel calorimeter was reproduced by placing the hadronic device downstream of the electromagnetic calorimeter. The first combined test has been done in 1994 and a second one, with the same prototypes, in 1996. The experimental setup is shown. In order to try to understand the energy loss in dead material between the active part of the LAr and the Tile detectors in 1996 test, a layer of scintillator was installed, called the midsampler. It consists of five scintillators, 20 cm x 100 cm each, fastened directly to the front face of the Tile modules. The scintillator is 1 cm thick, and is readout using ten 1 mm WLS fibers on each of the long sides. Electrons were reconstructed in the EM calorimeter for two purposes: to estimate the electron response in the EM section for the evaluation of the e/h ratio and to measure the energy resolution and linearity in order to verify the quality of the response. The fitted energy resolution, corrected for a beam momentum spread of 0.3 %, is: σ E /E (12.15 ± 0.23)%/ √E + (0.0 ± 0.20) % + (374 ± 54) MeV/E. The linearity is, within errors, better than 1%. The energy resolution for hadrons is affected by several factors: sampling fluctuations, the electronic
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Mehmet MERCAN
2015-11-01
Full Text Available Bu çalışmada; petrol ithalatçısı olan OECD üyesi seçilmiş 15 ülke için, 1960-2011 döneminde ham petrol ithal fiyatlarının enflasyon üzerindeki etkileri incelenmiştir. Analizde, herhangi bir ülkede meydana gelen bir makroekonomik şokun diğer ülkeleri de etkileyeceği varsayımını yani yatay kesit bağımlılığını dikkate alan panel birim kök ve eşbütünleşme testleri uygulanmış, seriler arasında eşbütünleşme ilişkisinin varlığı tespit edilmiştir. Uzun Dönem Eşbütünleşme Katsayıları Tahmin sonuçlarına göre ham petrol ithal fiyat artışları ve ekonomik büyümenin enflasyonu arttırdığı, ekonomik büyümenin enflasyonist etkisinin, ham petrol ithal fiyatlarının etkisinden daha fazla olduğu bulgusuna ulaşılmıştır.
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İlköğretim Okulu Öğrencilerinin Okul İklimine İlişkin Algılarını Yordayan Değişkenlerin İncelenmesi
ÖZDEMİR, SERVET; SEZGİN, FERUDUN; ŞİRİN, HÜSEYİN; KARİP, EMİN; ERKAN, SERDAR
2010-01-01
Bu çalışmada, ilköğretim okulu öğrencilerinin okul iklimine ilişkin algılarını yordayan değişkenlerincelenmiştir. Araştırmada; Afyon, Gümüşhane, Kocaeli, Konya, Mersin, Van ve Yozgat illerinden toplam 683 ilköğretimokulu öğrencisine “Okul İklimi Öğrenci Ölçeği” ve “Okul Atmosferi Ölçeği” uygulanarak elde edilen veriler kullanılmıştır.Çoklu hiyerarşik regresyon analizi sonuçları, kız öğrencilerin öğrenim gördükleri okulların iklimini erkek öğrencilere göredaha olumlu algıladıklarını göstermişt...
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Ahmet AKKAYA
2013-07-01
differently and efficiently, and to explain teachers the importance of orthographic mistakes. Yazım yanlışları, yazılı anlatımda iletişim sorunlarının ortaya çıkmasına neden olan önemli ögelerden biridir ve genellikle eğitim-öğretim ortamlarında öğrencilere öğretilmeye çalışılan yazılı anlatım kazanımlarındandır. Bu araştırmanın amacı, 6. sınıf öğrencilerinin sınav kâğıtlarında yaptıkları yazım yanlışlarının sıklığını ve Türkçe öğretmenlerinin yazım yanlışlarının nedenlerine ilişkin görüşlerini belirlemektir. Bu amaç doğrultusunda Adıyaman il merkezinden 2 ve köylerinden bir ortaokuldan tesadüfi olarak belirlenen 6. sınıfların 336 sınav kâğıdı incelenmiş ve bu araştırmanın verilerinin bir kısmı elde edilmiştir. Öğrencilerin 4142 yazım yanlışı yaptığı tespit edilmiştir. Öğrencilerin sınavlarda simgeleri, kısaltmaları, düzeltme işaretini, yabancı özel adları kullanmadığı; ek fiilin yazılışı ve fiil çekimiyle ilgili yanlış yapmadıkları; ünlü daralması ve ünlü türemesi ses olaylarının olduğu kelimeleri doğru yazdıkları görülmüştür. 6. sınıf öğrencilerinin en fazla büyük harflerin yazılışında yanlış yaptıkları tespit edilmiştir. Bununla birlikte sessiz harflerin yazılışı, sesli harflerin yazılışı, ses yutumu, bağlaç olan da, de'nin yazılışı ise en fazla tekrarlanan diğer yazım yanlışlarıdır. Öğrencilerin yaptığı yazım yanlışların nedenlerini belirlemek için de 6. sınıf Türkçe dersine giren 16 Türkçe öğretmenine “6. sınıf öğrencilerinin yazım yanlışlarının nedenleri nelerdir?” açık uçlu sorusu yöneltilmiş ve bu araştırmanın verilerinin diğer kısmı elde edilmiştir. Verilerin analiz edilmesinde içerik analizi tekniği kullanılmıştır. Türkçe öğretmenleri, 6. sınıf öğrencilerinin yazım yanlışlarının nedenlerinin ilgi ve dikkat eksikliğinden, temel dil
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Ayşe AYDOĞMUŞ
2012-02-01
Full Text Available Araştırmanın amacı, sosyal bilgiler öğretmenlerinin süreç odaklı ölçme ve değerlendirme araçlarını kullanma durumlarının incelenmesidir. Bu amacı gerçekleştirmek için, nicel araştırma yöntemlerinden genel tarama modelinden yararlanılmıştır. Araştırmanın örneklemini ise evrenden uygun örnekleme yöntemiyle seçilen 155 ilköğretim okulundaki 270 sosyal bilgiler öğretmeni oluşturmuştur. Araştırmacılar tarafından geliştirilen anketten elde edilen veriler, frekans, yüzde ve iki değişkenli “Ki Kare (χ2” testinden yararlanılarak yorumlanmıştır. Araştırma sonucunda; mesleki kıdem ile rubrik, kontrol listeleri, tutum ölçeği ve dilsiz harita kullanımında; mezun olunan kurum türü ile proje ile rubrik kullanımında; hizmet içi eğitimin proje, rubrik, gözlem formu ve dilsiz harita kullanımında anlamlı bir ilişki bulunmuştur. Ayrıca, süreç odaklı ölçme araçlarından performansın ve projenin sıklıkla kullanıldığı; yapılandırılmış grid, tanılayıcı dallanmış ağaç tekniği, tutum ölçekleri ve akran değerlendirmenin ise nadiren kullanıldığı görülmüştür. Öğretmenlerin bu araçları yeterince tanımadıkları sonucuna varılmıştır. Bu nedenle, konuyla ilgili öğretmenlere küçük gruplarla, uygulamalı hizmet içi eğitim seminerleri düzenlemesi; eğitim fakültelerinde bu araçların uygulamalı bir şekilde kullanılmasının öğretilmesi önerilmektedir.
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Romualdo Suzano Louzeiro Tiago
2008-02-01
Full Text Available INTRODUÇÃO E OBJETIVO: Realizar análise morfométrica das fibras mielínicas dos nervos laríngeos com a finalidade de verificar modificações quantitativas decorrentes do processo de envelhecimento. FORMA DE ESTUDO: Clínico e experimental. Material e Método: Foi coletado fragmento de 1cm dos nervos laríngeos superiores e nervos laríngeos recorrentes de 12 cadáveres do sexo masculino. A amostra foi dividida em dois grupos: idade inferior a 60 anos (Adulto e idade igual ou superior a 60 anos (Idoso. O material foi avaliado em microscópio de luz acoplado a sistema analisador de imagem. RESULTADOS: O número total de fibras mielínicas do nervo laríngeo superior foi semelhante nos dois grupos etários, mas com tendência para o maior número de fibras de 1µm no grupo adulto (p=0,0744. O grupo adulto apresentou maior número total de fibras mielínicas no nervo laríngeo recorrente (p=0,0006, e esta diferença ocorreu nas fibras com diâmetros de 1-3µm (pINTRODUCTION AND AIM: To carry out a morphometric analysis of myelinic fibers in laryngeal nerves aiming to identify quantitative changes as a result of aging. Study design: Clinical and experimental. MATERIAL AND METHOD: A 1cm fragment was collected from the superior laryngeal nerves and recurrent laryngeal nerves taken from twelve male cadavers. The sample was divided into two groups: those aged below 60 years (Adult and those aged 60 years or more (Elderly. The material was evaluated under light microscopy coupled with an image analysis system. RESULTS: The total number of myelinic fibers from the superior laryngeal nerve was similar in both age groups; there was, however, a trend for a higher number of 1μm fibers in the adult group (p=0.0744. The adult group had a higher total number of myelinic fibers in the recurrent laryngeal nerve (p=0.0006, and this difference was seen in fibers with diameters betwee 1-3μm (p<0.007. The adult group had a higher total number of myelinic fibers
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Lactococcus garvieae Suşlarının Antimikrobiyal Duyarlılıklarının Belirlenmesi
KUBILAY, Ayşegül; ALTUN, Soner; ULUKÖY, Gülşen; DILER, Öznur
2005-01-01
Bu çalışmada, 9 farklı Lactococcus garveiae suşlanmn Mueller-Hinton agarda disk diffüzyon tekniği ile ATB VET (Biomerieux 14 289) strip sistemi kullanılarak antimikrobiyal duyarlılıklarının yanısıra E testi (AB BIODISK) ile de Eritromycin antibiyotiğinin MIK(Minimal inhibitör konsantrasyonu) değerleri incelenmiştir. L.garvieae suşlarının; disk diffüzyon testi ve ATB VET sistemine göre Amoxicillin+clavulanic acid, Ampicillin, Enrofloxacin, Vancomycin, Tetracycline, Doxycycline, Chloramphenicol...
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Evolución del tipo de cambio peso mexicano/dólar estadounidense y el uso de derivados financieros
María de Lourdes Nájera López
2013-01-01
En este trabajo se analiza la evolución del tipo de cambio peso mexicano frente al dólar estadounidense, su volatilidad, así como el uso de los derivados financieros en las diferentes crisis que ha sufrido el país. Todo ello a partir de 1954 a la fecha, en donde se han registrado los regímenes de tipo de cambio: fijo, dual, de bandas de flotación y el de libre flotación. Se concluye que el tipo de cambio mexicano es volátil y que cualquier fenómeno económico o financiero externo repercute en ...
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Špiranec, Sonja
2012-04-01
olarakgörülen folksonomilerin gelişmesiyle değişmeye başlamıştır. Bu çalışmanın amacı etiketleme ve folksonominin etkisini araştırmaktır. Etiketlemenin esnek yapısı, kullanıcılara kendi dermelerindeki bilgi kaynaklarını faydalı buldukları yöntemlerle sınıflandırmalarına olanak sağlamaktadır. Buna rağmen farklı kişiselleştirilmiş kavramlar, arama yaparken ve görüntülerken bazı zorluklara nedenolabilmektedir. Etiketlemenin etkililiğini belirleyebilmek için, etiketlemenin doğası ve özel kullanıcı gruplarının etiketleme davranışı hakkında araştırma yapmak gereklidir. Bu araştırma, uzman ve deneyimsiz kullanıcılar arasındaki farkı belirlemeyi amaçlayan bir çalışmadan elde edilen bulguları sunmakta, ilgili alana katkı sağlamaktadır. Araştırma aynı zamanda, etiketleme veya indeksleme hakkında bilgisi olmayan ve “deneyimsiz kullanıcılar” olarak tanımlanan Üniversite 1. sınıf öğrencilerine sosyal işaretleme hizmeti sunan Delicious’da yer alan bir makale verilerek gerçekleştirilmiştir. Her öğrenciden, makalenin sadece başlık, alt başlık ve özünü bilerek onu etiketlemesi ve sonra makalenin tümünü okuyarak bir kez daha aynı işi yapması beklenmiştir. Aynı süreç Bilgi Bilim Bölümünde etiketleme ve indeksleme konusunda yeterli deneyim ve bilgiye sahip olan lisansüstü öğrencilerle tekrarlanmıştır. Deneyimli, orta düzeydeki ve deneyimsiz kullanıcıların etiketleme davranışları arasındaki farklılıklar ve benzerlikler bu yolla analiz edilmiş ve karşılaştırılmıştır. Araştırma, etiket numaraları ve etiket dağılımlarındaki farklılıkları ortaya koymaktadır. Uzman grubun etiketleme davranışlarında daha kesin ve daha tutarlı bulgulara rastlanmış, ayrıca uzun dönemde etiketleme eğitiminin folksonomilerin niteliğini artıracağı sonucu elde edilmiştir.
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Muhittin ELİAÇIK
2012-12-01
Full Text Available In the Ottoman Empire is seen even fatwas in verse written and it in the classical Turkish literature are instrumental to the emergence of a original poetry species. The word fatwa is derived from feta which means brave, young and strong; a difficult issue in the reply given to making a strong statement describes. Ifta, describes in the Ottoman Empire as an important public service by shayk al Islam to investigate an issue or put forward. In the Ottoman the fatwas of shaykh al Islams or muftis although are usually given Turkish and prose, but the in verse was given even. According to prose fatwas in verse fatwas very little has been written and came from pen of shaykh al Islams that has a specialplace among the poets of the Court. Bostanzādah Mehmed Effendi, oneof them. In Ottoman, during the Shaykh al-Islam Bostanzâde MehmedEffendi time, it has been many events that experienced firstly. His 52couplet in verse fatwa about coffee is a firstly experienced event and puta stop to an important discussion. Mehmed Effendi, besides being astrong dewan poet he has written many in verse fatwas. The coupletnumber of the questions and answers of this fatwas are very long andthat is very remarkable. In this article, four examples of his in versefatwas will be presented. Osmanlı’da fetvâların da manzum hâlde verilmiş olması, Klasik Türk Edebiyatı içinde orijinal bir nazım türünün ortaya çıkmasına ve farklı bir türün incelenmesine sebep olmuştur. Fetvâ kelimesi yiğit, genç, kavî anlamına gelen Arapça fetâ kökünden türemiş ve müşkil bir meselenin verilen cevapla güçlü bir şekilde izahının yapılmasını anlatmıştır. İftâ, Osmanlı’da mühim bir halk hizmeti olarak, bir meselenin hükmünün müftü veya şeyhülislamca araştırılarak ortaya konulmasını ifade etmiştir. Osmanlı’da şeyhülislâm veya müftülerin fetvâları genellikle Türkçe ve mensur hâlde verilmiş, ama orijinal bir şekil olarak
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Fan, Xiaobo; Supiwong, Weerayuth; Weise, Anja; Mrasek, Kristin; Kosyakova, Nadezda; Tanomtong, Alongkoad; Pinthong, Krit; Trifonov, Vladimir A; Cioffi, Marcelo de Bello; Grothmann, Pierre; Liehr, Thomas; Oliveira, Edivaldo H C de
2015-11-01
Comparative cytogenetic analysis in New World Monkeys (NWMs) using human multicolor banding (MCB) probe sets were not previously done. Here we report on an MCB based FISH-banding study complemented with selected locus-specific and heterochromatin specific probes in four NWMs and one Old World Monkey (OWM) species, i.e. in Alouatta caraya (ACA), Callithrix jacchus (CJA), Cebus apella (CAP), Saimiri sciureus (SSC), and Chlorocebus aethiops (CAE), respectively. 107 individual evolutionary conserved breakpoints (ECBs) among those species were identified and compared with those of other species in previous reports. Especially for chromosomal regions being syntenic to human chromosomes 6, 8, 9, 10, 11, 12 and 16 previously cryptic rearrangements could be observed. 50.4% (54/107) NWM-ECBs were colocalized with those of OWMs, 62.6% (62/99) NWM-ECBs were related with those of Hylobates lar (HLA) and 66.3% (71/107) NWM-ECBs corresponded with those known from other mammalians. Furthermore, human fragile sites were aligned with the ECBs found in the five studied species and interestingly 66.3% ECBs colocalized with those fragile sites (FS). Overall, this study presents detailed chromosomal maps of one OWM and four NWM species. This data will be helpful to further investigation on chromosome evolution in NWM and hominoids in general and is prerequisite for correct interpretation of future sequencing based genomic studies in those species.
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Xiaobo Fan
2015-11-01
Full Text Available Comparative cytogenetic analysis in New World Monkeys (NWMs using human multicolor banding (MCB probe sets were not previously done. Here we report on an MCB based FISH-banding study complemented with selected locus-specific and heterochromatin specific probes in four NWMs and one Old World Monkey (OWM species, i.e. in Alouatta caraya (ACA, Callithrix jacchus (CJA, Cebus apella (CAP, Saimiri sciureus (SSC, and Chlorocebus aethiops (CAE, respectively. 107 individual evolutionary conserved breakpoints (ECBs among those species were identified and compared with those of other species in previous reports. Especially for chromosomal regions being syntenic to human chromosomes 6, 8, 9, 10, 11, 12 and 16 previously cryptic rearrangements could be observed. 50.4% (54/107 NWM-ECBs were colocalized with those of OWMs, 62.6% (62/99 NWM-ECBs were related with those of Hylobates lar (HLA and 66.3% (71/107 NWM-ECBs corresponded with those known from other mammalians. Furthermore, human fragile sites were aligned with the ECBs found in the five studied species and interestingly 66.3% ECBs colocalized with those fragile sites (FS. Overall, this study presents detailed chromosomal maps of one OWM and four NWM species. This data will be helpful to further investigation on chromosome evolution in NWM and hominoids in general and is prerequisite for correct interpretation of future sequencing based genomic studies in those species.
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Burcu İLTER
2016-04-01
Full Text Available Ekonominin birçok alanında, hem kullanıcı temelli inovasyonun hem de açık inovasyonun, geleneksel olarak firmaların kendi bünyelerinde gerçekleştirdikleri inovasyon faaliyetleri ile rekabet ettiğini ve onun yerini alabileceğini gösteren örnekler giderek artmaktadır. Bu durum göz önüne alındığında, kullanıcıların inovasyon sürecine dahil edilmesinin önemi anlaşılmaktadır. Bu süreçte, geleneksel araçların yanı sıra, çevrimiçi araçların da şirketler tarafından sıklıkla kullanıldığı görülmektedir. Ülkemizde yapılmış olan çalışma sayısının yetersiz olması ve konunun inovasyon çalışmalarının geleceği açısından önem taşıdığının düşünülmesi sebebiyle bu çalışmada, çevrimiçi kullanıcı inovasyon araçları hakkında detaylı bir literatür araştırmasına yer verilmiş ve Fortune ilk 500 Türkiye listesinde yer alan şirketlerin, kullanıcılarını inovasyon süreçlerine dahil ederken söz konusu araçları ne ölçüde kullandıkları belirlenmiştir. Bulgular, kullanıcılardan daha çok ürün fikri geliştirme aşamasında faydalanıldığını, şikayet kutuları, pazar istihbarat hizmetleri ve dilek öneri kutularının, firmalar tarafından en çok kullanılan çevrimiçi araçlar olduğunu ve çevrimiçi şikayet kutusu ve inovasyon araç takımları kullanımının sektörler arasında farklılık gösterdiği göstermektedir. Bu çalışmanın ülkemizde çevrimiçi kullanıcı inovasyon araçlarına yönelik farkındalığı arttırması beklenmektedir. Considering the examples illustrating the fact that both user innovation and open innovation compete and substitute innovation undertaken by producers, the importance of user integration into innovation process becomes obvious. Throughout this process, along with traditional methods, firms also benefit from web based user innovation tools. Regarding the gap of number of researches on web based user
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Victor José Barbosa Santos
2006-06-01
Full Text Available Distonia laríngea, ou disfonia espasmódica, é caracterizada por contrações involuntárias e inapropriadas da musculatura responsável pela fonação, sendo a do tipo adutora a mais comum. Caracteriza-se por quebras fonatórias, sendo seu diagnóstico confirmado por videolaringoestroboscopia. O tratamento de escolha é feito com a aplicação direta de toxina botulínica nos músculos responsáveis pelo movimento incoordenado. O objetivo desse trabalho é relatar o caso de uma paciente com diagnóstico de distonia laríngea do tipo adutora, tratada com toxina botulínica e discutir as vantagens e observações descritas na literatura a respeito desse tratamento.Laryngeal dystonia or spasmodic dysphonia is characterized by involuntary and innapropiate spasms of vocal muscles, having the adductor type as the most common one. It is chacterized by strain-strangled voice with pitch breaks. Diagnosis is made by means of videolaryngostroboscopic exam. The treatment of choice is done with botulinum toxin directly injected in the muscles responsible for the mismatched movement. The aim of this study is to report on an adductor- type dysphonia patient and to discuss the advantages and observations about this treatment reported in the literature.
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Talts, Katrin
2006-01-01
Rootsi näitekirjaniku Lars Noréni kahest uuest näidendist, mida ühendab pealkiri "Terminaal"; Londoni teatris Duke of York esietendunud Sándor Márai romaanil "Küünlad põlevad lõpuni" põhinevast lavastusest "Hõõguvad söed" (dramatiseerija Ch. Hampton, lavastaja M. Blakemore), peaosas Jeremy Irons ; Berliinis 5.-21. maini peetavast teatrifestivalist "Theatertreffen" ; Brightoni festivalist 6.-28. mail ja Bonni biennaalist 13.-21. mail
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Abdülkadir ÖZTÜRK
2016-11-01
Full Text Available Özet Bu çalışmanın amacı, tüketicilerin helal kavramını nasıl algıladıkları ve tüketicilerin helal özellikli ürünleri satın alma davranışlarını incelemektir. Sosyal bilimlerde insan davranışlarını incelemede sıklıkla kullanılan Planlı Davranış Teorisi (PDT çerçevesinde araştırma yürütülmüştür. Tüketicilerin helal ürünlere yönelik tutumları, çevrelerindeki insanların tepkileri ve algılanan davranışsal kontrolün davranışsal niyet ve fiili davranış üzerindeki etkileri araştırılmıştır. Ayrıca tüketicilerin helal ürün kavramını nasıl tanımladıkları ve farklı ürün gruplarına göre bu tanımlamaların değişip değişmediği incelenmiştir. Bu amaçlar kapsamında helal tüketim ile ilgili sosyal medya üzerinde oluşturulmuş bir grubun üyelerine yönelik online olarak bir anket hazırlanmış ve gerekli veriler toplanmıştır. 202 tüketiciden elde edilen veriler üzerinde analizler yapılmıştır. PDT esas alınarak geliştirilen araştırma modelinde yer alan değişkenlerin tüketicilerin helal ürün satın almaya yönelik niyetlerini ve davranışlarını açıkladığı tespit edilmiştir. Davranışsal niyet üzerinde tüketicilerin geliştirdikleri tutum, fiili davranış üzerinde ise niyetlerin en belirleyici değişkenler oldukları tespit edilmiştir. Gıda, kozmetik ve temizlik ürün gruplarında katılımcıların en çok gıda ürünlerinin helal özelliği taşıması konusunda hassasiyet taşıdıkları gözlemlenmiştir. Helal ürünlerin, İslam dininin kurallarına uygun olarak üretilmiş olmasının yanında tüketiciler tarafından güvenilir, sağlıklı ve temiz olarak algılandığı tespit edilmiştir. Anahtar Kelimeler: Helal tüketim, Planlı Davranış Teorisi.
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Translational research needs us to go back to basics and collaborate: interview with Lars Sundstrom.
Sundstrom, Lars
2016-09-01
Lars Sundstrom is Director of Enterprise and Translation at the West of England Academic Health Sciences Network [1] (UK), a Professor of Practice in Translational Medicine and Co-Director of the Elizabeth Blackwell Institute for Health Research at Bristol University [2] (UK), and an honorary Professor of Medicine at Cardiff University (UK). He has extensive experience in translational medicine and clinical neurosciences, holding positions at several eminent universities. He has also held executive and board-level positions at several SMEs, developing new therapeutics for neurological conditions and tools for drug discovery. He has also been an advisor to several UK and local government task forces and to the European Commission and the European Federation of Pharmaceutical Industry Associations. He was a founding member of the European Brain Council in Brussels, and set up the Severnside Alliance for Translational Research, developing a regional network partnership to link clinical and basic scientists. He was also involved in the creation of Health Research Wales.
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Esra Nergis Güven
2008-04-01
Full Text Available [Turkish abstract]Internet’in hızlı gelişmesi ve yaygınlaşması elektronik ortamda iş ve işlemleri hızlandırmış ve kolaylaştırmıştır. Elektronik ortamlarda depolanan, taşınan ve işlenen bilgilerin boyutunun her geçen gün artması ise bilgiye erişim ile ilgili birçok problemi de beraberinde getirmiştir. Kullanıcıların elektronik ortamda sunulan bilgilere erişmelerindeki hız ve doğruluk gereksinimi nedeniyle, bu ortamlarda tutulan bilgileri sınıflandırma ve kategorilere ayırma yaklaşımlarına ihtiyaç duyulmaktadır. Sayıları milyonun üzerinde olan arama motorlarının, kullanıcıların doğru bilgilere kısa sürede ulaşmasını sağlaması için her geçen gün yeni yaklaşımlar ile desteklenmesi gerekmektedir. Bu çalışmada, web sayfalarının belirlenen konulara göre sınıflandırılabilmesi için, Çok Katmanlı (MLP yapay sinir ağı modeli kullanılmıştır. Özellik vektörü içeriğinin seçimi, yapay sinir ağının eğitilmesi ve son olarak web sayfalarının doğru kategorize edilmesi için bir yazılım geliştirilmiştir. Bu zeki yaklaşımın, elektronik ortamlarda bilgilerin kolaylıkla ve yüksek doğrulukla sınıflandırılması, web ortamlarında doğru içeriğe ulaşılması ve birçok güvenlik açığının giderilmesine katkılar sağlayacağı değerlendirilmektedir. [English abstract]Recent developments and widespread usage of the Internet have made business and processes to be completed faster and easily in electronic media. The increasing size of the stored, transferred and processed data brings many problems that affect access to information on the Web. Because of users’ need get to access to the information in electronic environment quickly, correctly and appropriately, different methods of classification and categorization of data are strictly needed. Millions of search engines should be supported with new approaches every day in order for users to get access to
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Problem Davranışların Azaltılmasında Olumlu Davranışsal Destek Planı Hazırlama
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Dilek Erbaş
2002-07-01
Full Text Available Günümüzde problem davranışlara, normal gelişim gösteren ve özürlü çocuklarda oldukça sık rastlanılmaktadır. Problem davranışlar öğrencilerin yaşamlarını farklı şekillerde olumsuz olarak etkilemekledir. Problem davranış gösteren bireyler bit davranışları nedeniyle, eğitim ve öğretim olanaklarından yeterince yararlanamamaktadır. Ayrıca, bu bireyler akranları ve toplumdaki diğer bireyler tarafından dışlanabildikleri için bazı sosyal becerileri geliştirememekle ya da sınırlı düzeyde geliştirebilmekledirler. Dolayısıyla, öğretmenler, öğrencilerin yaşamlarını olumsuz etkileyen bu davranışları azaltmak için, olumlu davranışsal destek planı hazırlamalıdır. Hazırlanan bu planlar, uygulamalı davranış analiz ilkelerine dayalı olmalıdır. Ayrıca, hazırlanan planın Öğrenciye ve uygulayacak bireylerin değer yargılarına uygun olması gereklidir. Olumlu davranışsal destek planının sahip olması gereken diğer önemli bir özelliği ise, hazırlanan planın. Öğrencinin yaşam kalitesini arttıracak şekilde desenlenınesi ve uygulanmasıdır. Kapsamlı bir plan hazırlamak için, planı ayrıntılı şekilde yazmak, tutarlı ve sistemli olarak uygulamak ve planın etkililiğini değerlendirmek ve gerektiğinde düzenlemeleri yapmak için veri toplamak gibi basamakları gerçekleştirmek gereklidir. Problem behaviors are frequently seen among the children with normal development as well as children with disabilities- Problem behaviors affect the students' lives in different negative ways. Individuals exhibiting problem behaviors cannot make the most out of their educational opportunities due to their behaviors. What's more, these individuals may run the risk of being incompetent or restricted İn some social skills because of being excluded by their peers. Thus, teachers should prepare behavior-changing plans based on positive behavior support to mitigate the problem behaviors
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Kesici Delici Alet Yaralanması ile İlişkili Saldırıların Analizi Manisa’da On Yıllık Deneyim
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Mehmet Sunay Yavuz
2011-08-01
Full Text Available Kişilerarası şiddet ile ilişkili olarak kesici-delici alet yaraları halen dünyanın pek çok ülkesinde başlıca problemlerden biri olarak kabul edilmesine rağmen, Türkiye'de sıklığı henüz belirlenmemiştir. Bu çalışmamn amaçları; kesici-delici alet yaralanmaları ile ilişkili saldırıların, mağdur ve faillerin analizini yapmak; daha önce yayımlanmış veriler ile karşılaştırmak ve Türkiye için ııygun önlemleri tanımlamaktır ve bu amaçla 238 kesici-delici alet saldırısı olgusu, 2002 ve 2012 arasında Celal Bayar Üniversitesi Hastanesi Adli Tıp Polikliniği'nde değerlendirilmiştir. Mağdurların ve saldırganların çoğu erkekti (%94.5; %96.5ve 20-39 yaş aralığında idi (%60.1; %67.3. Kesici-delici alet yaralarının büyük bölümü bıçak ve çakılar ile oluşturulmuştu (%81. Saldırılar çoğunlukla caddelerde (%40.3 ve halka açık alanlarda (%36.2 ve gece saatlerinde (%3 1.1 meydana gelmişti. Yaralanmaların çoğu yumuşak doku yaralanmaları (%73.8 idi ve genellikle intratorasik organlar ve/veya damarlar (%40.8 etkilenmişti. Mağdurların %37,4'ü yaşamsal tehl ikeye, %21 'i çeşitli sekellere manız kalmıştı. Suç önleme çabalan bağlamında, kesici-delici alet ile saldırılann gerçek çözümünde; eğitsel, sosyo-kültürel ve ekonomik çabaların yanı sıra; bıçak taşımaya karşı mevzuatın yürürlüğe konulması ve özellikle geceleri olmak üzere sokaklarda ve kamuya açık yerlerde polis denetimlerinin arttırılması önem taşımaktadır. Anahtar kelimeler: Şiddet, yaralar, bıçak, suç, adli tıp
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Muzaffer Eskiocak
2011-09-01
Full Text Available Amaç: Bu çalışma, mevsimsel grip aşısına (MGA ücretsiz erişen insanların tutum ve davranışlarını, yine ücretsiz, ama çeşitli tartışmalara konu olan pandemik grip aşısı (PGA karşısındaki tutum ve davranışlarıyla karşılaştırmak amacıyla yapılmıştır. Yöntem: Araştırma tanımlayıcı tipte bir araştırmadır ve Kırklareli-Evrensekiz Sağlık Ocağı bölgesinde, Şubat,2009–Şubat,2010 tarihleri arasında yürütülmüştür. Çalışma anketi yüz-yüze görüşme yöntemiyle doldurulmuştur. Bulgular: Katılımcıların %99,2’si (n=125 kamu kurumlarının ücretsiz MGA sağlamasını destekliyordu ve tamamı (N=126 gelecek yıl da ücretsiz MGA temin edilmesini istiyordu. 2010 yılında yapılan ikinci ankette ücretsiz sağlanan PGA olanların oranının ise %4 (n=5 olduğu tespit edildi. Sonuç: Bağışıklama hizmetlerinden yararlanmada ekonomik faktörlerin çok önemli olduğu, ancak toplumun güven duygusunun zedelenmesinin, ücretsiz sağlansa da aşılamayı ciddi düzeyde engellediği saptanmıştır.Anahtar Kelimeler: Mevsimsel grip aşısı, pandemik grip aşısı Attitudes and behaviors related to free pandemic influenza vaccination of who gets vaccinated with free seasonal influenza vaccine Objective: This study aims to compare attitudes and behaviors of the people who receive free Seasonal Influenza Vaccine (SIV with their attitudes and behaviors against Pandemic Influenza Vaccine (PIV which is also free, but controversial. Method: This study is a descriptive survey which was carried out within the service area of Evrensekiz Primary Healthcare Center (PHC in Kırklareli province and it was conducted between February 2009 and February 2010. The questionnaire has been applied by face to face interviews. Results: 99,2%of participants (n=125 supported providing free influenza vaccine by governmental organizations and all of them (N=126 wanted to get free influenza vaccine the next year
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Luna Descalzo, Margarita; Corbella i Corbella, Jacint
1987-01-01
La patologia tòxica per fòsfor és ben coneguda i pot tenir aspectes diversos tant pel que fa a les formes clíniques derivades dels seus compostos com per la prevalença diferent en unes o al tres èpoques. Aquí volem descriure l'impacte que va tenir una forma que avui té un interès gairebé només històric en paisos de bon nivell sanitari, però que va constituir un punt candent de la patologia laboral del segle XIX. Es tracta de les lesions de la boca: mucosa, dents i sobre tot maxil·lars en treb...
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Biersmith, Bridget H.; Hammel, Michal; Geisbrecht, Erika R.; Bouyain, Samuel
2011-01-01
Neurogenesis depends on exquisitely regulated interactions between macromolecules on the cell surface and in the extracellular matrix. In particular, interactions between proteoglycans and members of the type IIa subgroup of receptor protein tyrosine phosphatases underlie critical developmental processes such as the formation of synapses at the neuromuscular junction and the migration of axons to their appropriate targets. We report here the crystal structures of the first and second immunoglobulin-like domains of the Drosophila type IIa receptor Dlar and its mouse homologue LAR. These two domains adopt an unusual antiparallel arrangement that has not been previously observed in tandem repeats of immunoglobulin-like domains and that is presumably conserved in all type IIa receptor protein tyrosine phosphatases. PMID:21402080
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Zampieri Sueli A.
2002-01-01
Full Text Available Objetivo: deste estudo foi verificar os ajustes laríngeos realizados por cantores profissionais do gênero popular durante a imitação do canto em estilo lírico uma vez que muitas vezes ao ouvirmos um cantor popular interpretar uma música clássica percebemos que o mesmo faz modificações em sua qualidade vocal, tentando se aproximar, por imitação, do canto lírico. Forma de estudo: Clínico prospectivo. Material e método: Foram analisados 26 cantores profissionais do gênero popular, 10 homens e 16 mulheres, atuantes em baile. Foi aplicado questionário sobre perfil vocal, realizada análise perceptivo-auditiva e acústica das vozes e avaliação nasofibrolaringoscópica para análise da configuração laríngea nos estilos de canto popular e lírico. Resultado: A análise perceptivo-auditiva revelou que, ao cantar um trecho de música em estilo lírico, o cantor popular muda a qualidade vocal, aumentando o vibrato, o volume vocal, melhorando a ressonância vocal e sobrearticulando mais as palavras. Na análise espectrográfica não foi observada a ocorrência do formante do cantor em nenhuma das vozes. O ajuste laríngeo realizado por cantores populares ao imitarem o estilo de canto lírico foi predominantemente o aumento das constrições ântero-posterior e mediana sendo que a constrição mediana ocorreu mais no sexo masculino. Os valores de jitter e shimmer reduziram significantemente na vogal cantada em relação à vogal falada nas vozes femininas.
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Modelo Ovino de Suspensión Laríngea para Disfagia Orofaríngea Severa
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cristina Martin Villares
2018-05-01
Full Text Available Resumen Introducción y objetivo: la literatura científica ha validado el uso del model ovino no vivo para estudio e investigación de la disfagia orofaríngea severa. A partir de este modelo quirúrgico experimental, proponemos evaluar la eficacia de varias t?cnicas quirúrgicas indicadas en pacientes con disfagia orofaringea crónica y aspiración intratable que ocasionalmente se realizan en enfermos muy seleccionados . Material y Método: Realizamos comparación de riesgo de aspiración en 4 t?cnicas quirúrgicas indicadas para el tratamiento de disfagias severas con aspiración intratable: la tiroplastia de medialización, la traqueotom?a con sutura de ambas cuerdas vocales, la miotomía del cricofaríngeo y la suspensión laríngea. La valoración de la aspiración en los diferentes modelos quirúrgicos experimentales se realizará mediante 20 ml de líquido coloreado introducido en bolos por cavidad orofaríngea. Resultados: La combinación de Suspensión Laríngea con Miotomía del músculo Cricofaríngeo consigue la mejor protección de la vía aerea en el modelo experimental ovino frente a las otras técnicas propuestas. Conclusiones: El modelo ovino no-vivo nos ha permitido realizar una valoración inicial de resultados de diferentes técnicas quirúrgicas que intentan evitar la aspiración intratable de los pacientes con disfagia orofaríngea severa. A pesar de las limitaciones evidentes del modelo experimental, el trabajo sobre este modelo nos permite iniciar una línea de trabajo sobre técnicas quirúrgicas rehabilitadoras que ayuden pacientes neurológicos seleccionados mantener la ingesta oral.Palabras clavesuspension laringea disfagia orofaríngea modelo experimentaSummarySurgical treatment ca be considered in chronic oropharyngeal dysphagy withh sever aspiration. Several sugical techniques can be performed in occassionally and high selected patients. The aim of this study is to evaluate the risk of aspitaion of various
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Öğrenci Anılarında Tarih Öğretmenleri ve Uygulamaları (1882-1957
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Bahri Ata
2012-10-01
Full Text Available Özet: Anılar, tarih eğitimi alanı tarihinin en önemli kaynaklarındandır. Bu makalenin amacı, Türk kültürümüze damgasını vurmuş ve vurmakta olan kişilerin 1882’den 1957’ye kadar dönemi kapsayan anılarından hareket ederek, geçmiş yıllarda okullardaki tarih öğretmenlerinin sınıf içi ve sınıf dışı tarih öğretimi uygulamalarını ortaya çıkarmaktır. Bunun için 15 tarihi okuldan mezun olmuş, 25 kişinin anısı tarandı. 22 tarih öğretmeni saptandı. Her okulun ve her tarih öğretmeninin kendine özgü (sui generis olmasından hareketle, mümkün olduğunca veriler, özel şartları içinde değerlendirilmeye çalışıldı. Elimizdeki bu anılarla, geçmişteki tarih öğretiminin büyük resminin çekildiğinin iddiasında değilim. Öte yandan bu sınırlı sayıdaki anılar antolojisi, tarih öğretmenlerinin şahsiyeti, giyim kuşamı, sınıf içi davranışları, ders kitabı kullanımı, öğrencilerle iletişimleri hakkında pek çok bilgi vermektedir. Bu anı sahiplerinin genelde tarih öğretmenleri ve uygulamaları açısından kendilerini şanslı hissettiklerini yer yer yetişkinliklerinde tarih öğretmenlerini acımasızca eleştirdikleri görülmektedir. Anılardan anlaşıldığı kadarıyla, Türkiye’de de yılmayan, sanatçı ruhlu, tarihi yaşamış gibi anlatan tarih öğretmenlerinin akılda kalıcı olduğu anlaşılmaktadır. Genelde tarih öğretmenlerinin sınıf içinde anlatım tekniğini çok etkileyici kullandıkları anlaşılmaktadır. Öğrenciler, tarih öğretmenlerinin büyük fedakârlıklarla yaptıkları iyi uygulamaları, üzerinden yıllar geçmesine rağmen hatırlamaktadır. Geçmişte, tarih derslerinde Fransız Devrimine çok önem verildiği anlaşılmaktadır. Bazı tarih öğretmenlerinin bir rehber öğretmeni gibi davranıp, öğrencilerinin meslek seçimlerini de oldukça etkilediği görülmektedir. Bu türden anılardan oluşan bir
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Vásquez Galán, Belem Iliana; Calderón Villarreal, Cuauhtémoc
2017-01-01
Resumen Este es un análisis del efecto que tiene una fluctuación del tipo de cambio renminbi-dólar sobre las exportaciones mexicanas dirigidas al mercado estadounidense y sobre la inversión extranjera directa procedente de ese país. Las estimaciones de un vector de corrección de error, con datos de 1995 a 2015, indican que una depreciación del renminbi reduce el crecimiento de las exportaciones mexicanas en 2.01 por ciento, pero no tiene efecto sobre la IED. Esto implica que, al ser competido...
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"DUMONT DAYOT, N; The ATLAS collaboration; "CAP, S; "DUMONT DAYOT, N; "FOURNIER, L; "LETENDRE, N; "PERROT, G; "Wingerter, I
2011-01-01
In the context of the LHC upgrades, a new Read-Out Driver (ROD) board for the ATLAS LAr calorimeter is being developed. xTCA (Advanced/Micro Telecom Computing Architecture) is becoming a standard in high energy physics and is a serious candidate for future readout systems. We will present our current developments to master ATCA and to integrate a large number of very high speed links (96 links/8.5 Gbps) on a ROD Evaluator ATCA board. To manage our ROD Evaluator, we have developed a versatile ATCA IPMI controller for ATCA boards which is FPGA Mezzanine Card (FMC) compliant.
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Charge Sensitive Amplifier (CSA) in cold gas of Liquid Argon (LAr) Time Projection Chamber (TPC)
International Nuclear Information System (INIS)
Bechetoille, E; Mathez, H; Zoccarato, Y
2011-01-01
This paper presents our work on a 8-channel low noise Front-End electronic coupled to a Liquid Argon (LAr) TPC (Time Projection Chamber). Each channel consists of a Charge Sensitive Amplifier (CSA), a band pass filter and a 50 Ohms buffer as line driver. A serial link based on a 'i2c-like' protocol, provides multiple configuration features to the circuit by accessing slow control registers. In this paper, we describe the CSA, the shaper and the slow control part. The feedback network of the CSA is made of a capacitance and a resistor. Their values are respectively 250 fF and 4 MΩ. An input referred noise of, at most, 1500 e- rms must be achieved at -100 deg. C with an input detector capacitance of 250 pF to ensure a correct measurement of the minimal signal of 18000e- (2.88 fC). The power consumption in this cryogenic setup must be less than 40 mW from a 3.3 V power supply.
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Carla Aparecida Cielo
2011-04-01
Full Text Available TEMA: Características da bulimia nervosa (BN e do Refluxo Laringofaríngeo (RLF e alterações vocais e laríngeas que podem decorrer da exposição da laringe ao ácido gástrico. OBJETIVO: Descrever, por meio de revisão de literatura, as características do RLF e da BN, relacionando-os com as alterações vocais e laríngeas que podem se originar da exposição da laringe ao ácido gástrico que ocorre em ambas as condições. CONCLUSÃO: A BN se caracteriza por um transtorno alimentar de causa principalmente psicológica em que ocorre ingestão compulsiva de grande quantidade de alimentos, seguida de episódios de vômitos auto-induzidos com a finalidade de evitar o ganho de peso. O RLF consiste em uma variação clínica da DRGE, na qual o fluxo retrógrado do alimento e do ácido gástrico entra em contato com a laringe e suas estruturas. Em comum, a BN e o RLF apresentam este mecanismo de regurgitação que pode atingir a laringe. Dentre os sinais e sintomas laríngeos e vocais decorrentes da regurgitação do ácido gástrico sobre a laringe estão: globus faríngeo, disfonia, rouquidão, tosse seca, disfagia, halitose, lesões inflamatórias nas pregas vocais, laringite, amigdalite, edema e eritema glótico posterior e ou de aritenóides, da região retrocricóidea e interaritenóidea, estenose subglótica, irregularidades na mucosa das pregas vocais, hipertrofia de mucosa laríngea, leucoplasia, carcinoma, laringoespasmos, granulomas, úlcera de contato, nódulos vocais, pólipos vocais, edema difuso, granuloma, fixação uni ou bilateral de aritenóides, edema de Reinke, laringomalácia, estridor, e odinofagia.BACKGROUND: Characteristics of bulimia nervosa (BN and laryngopharyngeal reflux (LPR and laryngeal and voice disorders that can arise from exposure to gastric acid of the larynx. PURPOSE: To describe, through literature review, the characteristics of LPR and the BN, linking them with laryngeal and voice disorders that can stem
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Milligan, Lauren A; Bazinet, Richard P
2008-12-01
Brain growth in mammals is associated with increased accretion of long-chain polyunsaturated fatty acids (LCPUFA) in brain phospholipids. The period of maximum accumulation is during the brain growth spurt. Humans have a perinatal brain growth spurt, selectively accumulating docosahexaenoic acid (DHA) and other LCPUFA from the third trimester through the second year of life. The emphasis on rapid postnatal brain growth and LCPUFA transfer during lactation has led to the suggestion that human milk LCPUFA composition may be unique. Our study tests this hypothesis by determining fatty acid composition for 11 species of captive anthropoids (n=53; Callithrix jacchus, Cebus apella, Gorilla gorilla, Hylobates lar, Leontopithecus rosalia, Macaca mulatta, Pan troglodytes, Pan paniscus, Pongo pygmaeus, Saimiri boliviensis, and Symphalangus syndactylus). Results are compared to previously published data on five species of wild anthropoids (n=28; Alouatta paliatta, Callithrix jacchus, Gorilla beringei, Leontopithecus rosalia, and Macaca sinica) and human milk fatty acid profiles. Milk LCPUFA profiles of captive anthropoids (consuming diets with a preformed source of DHA) are similar to milk from women on a Western diet, and those of wild anthropoids are similar to milk from vegan women. Collectively, the range of DHA percent composition values from nonhuman anthropoid milks (0.03-1.1) is nearly identical to that from a cross-cultural analysis of human milk (0.06-1.4). Humans do not appear to be unique in their ability to secrete LCPUFA in milk but may be unique in their access to dietary LCPUFA.
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Genetiği Değiştirilmiş Tohum Yağları ve Özellikleri
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Şükran Kuleaşan
2015-02-01
Full Text Available Günümüzde genetik mühendisliğinin tarımsal uygulamalardaki gelişimi sayesinde yağ bitkilerinde genetik modifikasyonlar yapılarak tohum yağının yağ asidi kompozisyonunu belirlemek olanaklı hale gelmiştir. Dünya'da bitkisel yağ üretiminin yaklaşık olarak 87 milyon ton olduğu bildirilmektedir. Bu üretimin ekonomik değeri ise 40 milyar Amerikan Doları'dır. Yağların insan beslenmesindeki öneminin yanı sıra bitkisel yağ asitleri, sabun, deterjan, gres, biyoyakıt, kozmetik ve boya sanayi için de hammadde niteliğindedir. Bu nedenle bitkisel yağlara olan ilgi son yıllarda giderek artmaktadır. Ayrıca bitkisel üretim fazlası yağın, petrole alternatif olarak kullanılabileceği de belirtilmektedir.
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Doğa Başar SARIİPEK
2017-05-01
Full Text Available İhtiyaç, somutlaştırılması ve tanımlanması güç bir kavramdır. Bu bağlamda, ihtiyaçların hangi ölçütlere göre belirleneceği, temel ve ileri ihtiyaçların neler olduğu, ihtiyaç içinde olanlarla olmayanların neye göre ve nasıl kesin olarak ayrılacağı gibi sorular sosyal refah ve koruma politikaları tasarlanırken sürekli sorulan ve tartışılan sorulardır. İhtiyaç temelli yaklaşım bu sorulara cevap olarak geliştirilmiş bir sosyal koruma yaklaşımıdır. Ancak genel anlamda ihtiyaç kavramının özünde bulunan sübjektif nitelikler ve içerdiği belirsizlikler nedeniyle, uygulaması kolay bir yöntem değildir. Bu nedenle, uygulamada herkesi kapsayabilmek adına “temel ihtiyaçlar” şeklinde bir daraltmaya gidilmiştir. Temel ihtiyaçlar yaklaşımının amacı, bireyin tam gelişimi için gereken fırsatları sağlamak ve bu amaçla belli gruplar için belli kaynakları tahsis etmektir. Temel ihtiyaçlar yaklaşımının özü, gerçek yaşam düzeyiyle ihtiyaçlar arasındaki boşluğun diğer alternatif yaklaşımlara göre çok daha kısa sürede ve mümkün olan en az miktarda kaynak kullanılarak doldurulmasıdır. Ancak bu yaklaşım, teoriden kaynaklanan ciddi eksiklikleri nedeniyle hak temelli yaklaşımın sağladığı sosyal koruma güvence düzeyini sağlamaktan uzak görünmektedir. / Needs are not easy to define. In this sense, the questions of which criteria are applied to determine needs, what the basic and further needs are, how the ones who are in need are distinguished from the others etc. are constantly asked while designing policies of social welfare and protection. Needs based approach is a social protection mechanism which was introduced as a response for these questions. Yet, it is not an easy measure to take due to the subjective features and uncertainties in the very nature of the concept of need itself. Therefore, a conceptual restriction, in the form of “basic needs”, was
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Phase II trial of SOM230 (pasireotide LAR) in patients with unresectable hepatocellular carcinoma.
Feun, Lynn G; Wangpaichitr, Medhi; Li, Ying-Ying; Kwon, Deukwoo; Richman, Stephen P; Hosein, Peter J; Savaraj, Niramol
2018-01-01
A phase II trial of pasireotide was performed to assess its efficacy and safety in advanced or metastatic hepatocellular carcinoma (HCC). Patients with advanced HCC and Child-Pugh score ≤7 received pasireotide LAR 60 mg intramuscularly every 28 days. Primary endpoint was disease control rate. Secondary endpoints were time to tumor progression, response rate, treatment-related adverse events, and overall survival. Serum insulin growth factor-1 was measured before and after pasireotide. Twenty patients were treated and evaluable. Eighteen patients (90%) had prior therapy; 16 patients (80%) had multiple therapies. Median age was 65, 75% had Barcelona Clinic Liver Cancer stage C, and 55% had metastatic disease. The main toxicity was hyperglycemia. Rare adverse effects included reversible grade 4 elevation in alanina transaminase/aspartate transaminase in one patient. The best response was stable disease in 9 patients (45%). Median time to tumor progression for the 20 patients was 3 months, and median survival was 9 months. Pasireotide had limited clinical benefit as second-line or third-line treatment in patients with advanced or metastatic HCC. Low baseline insulin growth factor-1 level may be indicative when SOM230 treatment may be ineffective, and decreasing levels after treatment may be indicative of disease control.
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Emel Çilingir
2016-12-01
Full Text Available The aim of study was to investigate the effects of Realistic Mathematics Education (RME based instruction in the elementary mathematics curriculum on the mathematics achievement, Visual Mathematics Literacy Self Efficiency Perceptions (VMLSP and Mathematics Problem Solving Attitude (MPSA. The study was determined as a quasi-experimental study which conducted as a pre-posttest design with a control group. The research was conducted with 147 students at fourth grade of a public elementary school in Adana. In the study, the experimental group and one of the control group were instructed by one of the researchers, while in other control group was instructed by their teacher. „Geometric Shapes‟ unit was instructed with RME at the experimental group while the current instructional method was conducted to the control groups. The data were obtained with mathematics achievement tests and VMLSP and MPSA Scale which provided goodness according to the confirmatory factor analysis model. The quantitative data was evaluated by using mixed ANOVA and tTest methods. As a result, it was found that the students at the experimental group have more successful in mathematic achievement tests and more progress on VMLSP and MPSA than control group. [Araştırmanın amacı, ilkokulda Gerçekçi Matematik Eğitimi yaklaşımıyla gerçekleştirilen öğretimin, öğrencilerin matematik başarılarına, görsel matematik okuryazarlık özyeterlik algılarına ve matematik problemlerini çözmeye yönelik tutumlarına etkisini incelemektir. Bu amaçla öntest-sontest kontrol gruplu yarı deneysel bir çalışma yapılmıştır. Araştırma, Adana’daki bir devlet ilkokulunun 4. sınıfına giden 147 öğrenci üzerinde gerçekleştirilmiştir. Araştırmada deney grubunda ve iki kontrol grubundan birinde dersler araştırmacı tarafından diğer kontrol grubunda ise sınıfın öğretmeni tarafından yürütülmüştür. Deney grubunda ‘Geometrik Şekiller’
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Giordania Gomes Campos
2004-12-01
Full Text Available Os tumores cartilaginosos da laringe são extremamente raros e correspondem a aproximadamente 1% dos tumores que acometem este órgão. Menos que 0,1% destes tumores correspondem aos condrossarcomas. Os condromas e os condrossarcomas de baixo grau são os mais freqüentemente encontrados e 70-75% destes tumores localizam-se na face laríngea da lâmina posterior da cartilagem cricóidea. O diagnóstico do condrossarcoma da laringe pode ser esquecido devido a sua baixa ocorrência e sua forma indolente de crescimento. A apresentação clínica é variada e diretamente dependente do tamanho e localização do tumor: estridor, cornagem, dispnéia, disfagia ou massa cervical são os sinais mais freqüentes. O objetivo deste estudo é apresentar um caso incomum de condrossarcoma laríngeo de origem na cartilagem tireóidea, discutindo o quadro clínico, o diagnóstico, tratamento e os fatores prognósticos.Cartilaginous tumors of the larynx are extremely rare neoplasms that account for approximately one per cent of all tumors of this organ. Less than 0.1% correspond to chondrosarcomas. Chondroma and low-grade chondrosarcoma are the most common, 70-75% of these tumors arise on the endolaryngeal surface of the posterior lamina of the cricoid cartilage. The diagnosis of laryngeal chondrosarcoma is likely to be missed because of its infrequent occurrence and its indolent pattern of growth. The clinical presentation is varied and directly dependent on size and location of tumor: stridor, hoarseness, dyspnea or neck mass are commonly presented signs. The objective of this study was to show an unusual case of laryngeal chondrosarcoma originating from thyroid cartilage, discussing its clinical presentation, diagnosis, treatment and prognosis.
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Sara Marino
2014-04-01
Full Text Available In this article I will review the film Dogville by Lars Von Trier through the perspective given by Hamid Naficy in his book An Accented Cinema: Exilic and Diasporic Filmmaking. The main purpose is to understand how identity is described and performed through the allegory of Grace and the image of the refugee, and the role homelessness and displacement play both for the filmmakers and the content of diasporic films. I will demonstrate how the relationship between minority (Grace-the refugee and the majority (the population of Dogville is a topic of transnational cinema, and which conclusions can we make by taking into account the role of identity and sense of belonging for transnational productions.
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OTA director to be Clinton's science advisor
Leath, Audrey
President Clinton has nominated John H. “Jack” Gibbons to be Assistant to the President for Science and Technology, and director of the White House Office of Science and Technology Policy (OSTP). For over a decade, Gibbons has served as director of the Office of Technology Assessment (OTA), a bipartisan research arm of Congress.In nominating Gibbons, Clinton said, “I am delighted to appoint a brilliant scientist and gifted administrator… It is profoundly important that the president have a science advisor who understands science, who understands technology, who understands the practical application of these disciplines to the myriad of problems we face today. And I can tell you that from [Vice-president] Al Gore on down to every other member of Congress I have discussed John Gibbons with, I have hardly ever received more glowing and more consistent recommendations for anyone.”
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Pocock, J G A
2016-01-01
Barbarism and Religion, the first half of J. G. A. Pocock's study of Gibbon's Decline and Fall, was designed to set Gibbon's work in context, using a method developed in Cambridge, by juxtaposing his narrative to many others-to some but not all of which he explicitly referred. Helena Rosenblatt has misunderstood Pocock's intent, which was to show that Gibbon's work took much of its inspiration for its treatment of Christianity from a world of ecclesiastical scholarship. Though Pierre Force shows that Voltaire's erudition was richer than has been thought, he and Gibbon pursued very different forms of learning. And though Pocock agrees with Jonathan Israel that many thinkers challenged traditional Christian theology, their efforts were far more varied than Israel holds. Brief studies of Jean LeClerc and Ralph call Israel's vision of radical Enlightenment into question.
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Bâbürnâme'deki Bazı Cümle Yapıları Üzerine Some Sentences Structure In Bâbürnâme
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Adnan Rüştü KARABEYOĞLU
2012-12-01
Full Text Available Diachronic and analytical studies of the historical syntax of Turkic languages, in referring to the subject matter of sentences, attempt to reveal the structures, properties and characteristics of Turkic sentence types and consider various aspects of them. These works, which analyse sentences in historical Turkic languages, generally deal with structure, subordinate clause types and characteristics. They also focus on the relationship between the main and subordinate clause, analysing the syntactical and semantical relationship -in Old Turkic, Medieval Turkic, Old Anatolian Turkish and Çağatay Turkic- by way of clause conjunctions: ammâ, bâvücûd, çü,çün, çün kim, egerçi, gerçi, herçi, her neçe, ne, neçük, neçükin, neçete,neçete kim, neteg, kaçan, kaçan kim, kaltı, kim, ki, takı tâ, tâ ki, vâkıa,vaktâ ki, vakt-î, velî, zîrâ etc.In this paper, we attempt to analyse some of the compoundsentence structures, clause conjunctions (egerçi-velî, bâvücûd, her néçe,néçük (kim and adversative clause types of Bâbürnâme, which is theprominent exemplar of Çağatay Turkic prose. This paper aims tocontribute to the body of works that have studied the historical syntaxof Turkic languages and also Bâbür’s style. Türkçenin tarihî söz dizimi üzerine yapılan art zamanlı incelemelerde cümle bahsi çeşitli yönleriyle ele alınır ve Türkçenin sahip olduğu cümle yapıları ve özellikleri ortaya konmaya çalışılır. Cümle bahsi ile ilgili yapılan bu çalışmaların ise genellikle birleşik cümle yapıları, yardımcı cümle türleri ve özellikleri ile baş ve yardımcı cümleler arasındaki ilişkiler üzerine odaklandığı ve bu suretle cümle yapılarının tahlili üzerinde durulduğu görülür. Türkçenin tarihî söz dizimi ile ilgili bu çalışmalarda az önce zikredilen hususlar yanında ayrıca baş ve yardımcı cümle türleri arasındaki söz dizimi ve aynı zamanda
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Simulating the gas hydrate production test at Mallik using the pilot scale pressure reservoir LARS
Heeschen, Katja; Spangenberg, Erik; Schicks, Judith M.; Priegnitz, Mike; Giese, Ronny; Luzi-Helbing, Manja
2014-05-01
LARS, the LArge Reservoir Simulator, allows for one of the few pilot scale simulations of gas hydrate formation and dissociation under controlled conditions with a high resolution sensor network to enable the detection of spatial variations. It was designed and built within the German project SUGAR (submarine gas hydrate reservoirs) for sediment samples with a diameter of 0.45 m and a length of 1.3 m. During the project, LARS already served for a number of experiments simulating the production of gas from hydrate-bearing sediments using thermal stimulation and/or depressurization. The latest test simulated the methane production test from gas hydrate-bearing sediments at the Mallik test site, Canada, in 2008 (Uddin et al., 2011). Thus, the starting conditions of 11.5 MPa and 11°C and environmental parameters were set to fit the Mallik test site. The experimental gas hydrate saturation of 90% of the total pore volume (70 l) was slightly higher than volumes found in gas hydrate-bearing formations in the field (70 - 80%). However, the resulting permeability of a few millidarcy was comparable. The depressurization driven gas production at Mallik was conducted in three steps at 7.0 MPa - 5.0 MPa - 4.2 MPa all of which were used in the laboratory experiments. In the lab the pressure was controlled using a back pressure regulator while the confining pressure was stable. All but one of the 12 temperature sensors showed a rapid decrease in temperature throughout the sediment sample, which accompanied the pressure changes as a result of gas hydrate dissociation. During step 1 and 2 they continued up to the point where gas hydrate stability was regained. The pressure decreases and gas hydrate dissociation led to highly variable two phase fluid flow throughout the duration of the simulated production test. The flow rates were measured continuously (gas) and discontinuously (liquid), respectively. Next to being discussed here, both rates were used to verify a model of gas
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Güliz Onat
2014-08-01
Full Text Available AbstractObjective: A health-promoting lifestyle has an especially important role during pregnancy due to its direct link to healthy births, and to low maternal-fetal mortality and morbidity rates. The objectives of our study are to determine and analyse the health-promoting lifestyles and related factors in pregnant women. Methods: This descriptive study was carried out on 255 pregnant women in the city of Usak in Turkey, using the Health-Promoting-Lifestyle-Profile-II-(HPLP. Frequencies, percentage distributions, t tests, and the Mann Whitney U test and ANOVA were used to analyze the results. Results: The mean age of the pregnant women was 26.7±5.1 and their mean gestational week was 25.2±10.9. The mean total score on the HPLP was 130.7±20.0. The lowest score was for “physical activity” (14.4±5.0. The highest score was for “psychological wellbeing” (26.18±4.2. Smoking prevalence among the study population was 17% before the pregnancy, and 3.9% during the pregnancy (with an average of 4 cigarettes/day. During the pregnancy diet habits improved. The rate of giving up smoking was high. Women also sought further knowledge about pregnancy and birth. Conclusions: In pregnant women the HPLP score was upper to intermediate in level. Of the women who participated in the survey, those that were unemployed, had a lower level of education, and those who had considered abortion were found to be at a higher risk of not having a health promoting life style. This finding provides a unique insight in identifying the risk group for health care providers who work at an antenatal clinic. Health caregivers should pay more attention to this risk group when evaluating healthy lifestyles during whole pregnancy. Key Words: Health-Promoting Lifestyles; pregnant women; Health Promoting Lifestyle Profile-IIÖzetAmaç: Sağlıklı yaşam biçimi davranışları; sağlıklı ve canlı bir doğum yapma, anne-yenidoğan mortalite ve morbidite oranını azaltma
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Padilha, Ana Caroline de Bassi
2014-01-01
Neste trabalho, temos como objetivo investigar as associações entre tecnologias domésticas e tipos de feminilidades na revista Casa & Jardim como mídia de pedagogias de gênero. O recorte de estudo tem como foco os discursos textuais e imagéticos sobre tecnologias do lar veiculados na revista Casa & Jardim durante as décadas de 1950 e 1960. Neste período, as revistas direcionadas para públicos femininos buscavam criar uma identificação das mulheres com o espaço e o consumo domésticos, apresent...
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Maximilien Brice
2008-01-01
Mr Lars Leijonborg, Minister for Higher Education and Research of Sweden visiting the cavern ATLAS, the control room of ATLAS and the machine LHC at Point 1 with Collaboration Spokesperson P. Jenni and Dr. Jos Engelen, Chief Scientific Officer of CERN.
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Kablosuz Duyarga Ağları ile Engelli İnsanlar İçin Akıllı Ev Uygulamaları
Işılak, Ali Haktan; Baydere, Şebnem
2011-01-01
Akıllı evler geleceğin tasarım kavramları arasında olmaktan çıkmıştır. Günümüzde, içinde yaşayanların yaşam tarzlarını doğrudan etkileyen evler tasarlanmaktadır. Akıllı ev sistemlerinin amacı, tanımlanmış aktivitelerin farkında olan bir ortam yaratmaktır. Engelli insanlar günlük hayatlarını kolaylaştırmak için bu sistemlere ihtiyaç duymaktadırlar. Bu çalışmada engelli insanların hayatlarını kolaylaştırmak amacıyla farklı engel türleri için duyarga ağları ile bazı akıllı ev uygulamaları gelişt...
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Directory of Open Access Journals (Sweden)
Noemi Grigoletto De Biase
2012-12-01
Full Text Available O diagnóstico de comprometimento do nervo laríngeo superior e de ramos do laríngeo recorrente demanda eletromiografia, pois as alterações à laringoscopia são inespecíficas. OBJETIVO: Avaliar eletrofisiologicamente a função dos nervos laríngeo superior e inferior por meio da atividade elétrica dos músculos por eles inervados, em pacientes com disfonia com coaptação incompleta das pregas vocais à fonação. MÉTODO: Estudo prospectivo; 39 indivíduos com disfonia e fechamento glótico incompleto foram submetidos à eletromiografia dos músculos tireoaritenóideo, cricotireóideo e cricoaritenóideo lateral bilateralmente. Foram avaliadas atividade de inserção, no repouso (fibrilação, onda positiva e fasciculação e durante contração voluntária dos músculos (recrutamento, amplitude e duração do potencial e latência entre início da atividade elétrica e a sonorização. RESULTADOS: Não observamos alteração na atividade de inserção e no repouso. Nenhum paciente apresentou recrutamento alterado. A média da amplitude dos potenciais elétricos esteve compatível com a normalidade nos músculos testados, assim como a duração do potencial e o tempo de latência entre o início da atividade elétrica e a sonorização. CONCLUSÃO: Não observamos sinais de desnervação nos músculos tireoaritenóideo, cricotireóideo e cricoaritenóideo lateral bilateralmente nos pacientes estudados.The lack of specificity in laryngoscopical examination requires that the diagnosis of superior laryngeal and recurrent laryngeal nerve involvement be carried out with the aid of electromyography. OBJECTIVE: This study aims to assess the electrophysiological function of the superior and inferior laryngeal nerves by measuring the electrical activity of the muscles they innervate in dysphonic patients with incomplete closure of the vocal folds during phonation. METHOD: Thirty-nine patients with incomplete glottic closure were enrolled in a
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The interpretive power of infraorbital foramen area in making dietary inferences in extant apes.
Muchlinski, Magdalena N; Deane, Andrew S
2014-08-01
The infraorbital foramen (IOF) is located below the orbit and transmits the sensory infraorbital nerve (ION) to mechanoreceptors located throughout the maxillary region. The size of the IOF correlates with the size of the ION; thus, the IOF appears to indicate relative touch sensitivity of maxillary region. In primates, IOF size correlates well with diet. Frugivores have relatively larger IOFs than folivores or insectivores because fruit handling/processing requires increased touch sensitivity. However, it is unknown if the IOF can be used to detect subtle dietary differences among closely related hominoid species. Hominoids are traditionally grouped into broad dietary categories, despite the fact that hominoid diets are remarkably diverse. This study examines whether relative IOF size is capable of differentiating among the dietary preferences of closely related species with overlapping, yet divergent diets. We measured IOF area in Hylobates lar, Symphalangus syndactulus, Pongo pygmaeus spp., Pan troglodytes, Gorilla gorilla, Gorilla beringei graueri, and Gorilla beringei beringei. We classified each species as a dedicated folivore, mixed folivore/frugivore, soft object frugivore, or hard object frugivore. The IOF is documented to be larger in more frugivorous species and smaller in more folivorous taxa. Interestingly, G.b. beringei, had the largest relative IOF of any gorilla, despite being a dedicated folivore. G.b. beringei does have unique food processing behavior that relies heavily on maxillary mechanoreception, thus this finding is not entirely unsupported behaviorally. The results of this study provide evidence that the IOF is an informative feature in interpretations of fossil apes. Copyright © 2014 Wiley Periodicals, Inc.
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El ojo infecto de la televisión. A propósito de Riget de Lars von Trier
Directory of Open Access Journals (Sweden)
Laura Odello
2014-01-01
Full Text Available Riget, la serie de televisión de dos temporadas dirigida por Lars von Trier entre 1994 y 1997, pone en escena un hospital acechado por fantasmas y una comunidad científica atrapada por sus propias supersticiones. Guiada por estaserie el artículo explora la contaminación de la mirada médica así como la contaminación de los ojos de los espectadores. Al reflexionar sobre la práctica de la autopsia, Foucault describió la mirada médica como ver la vida a travésdel espejo de la muerte, el “gran analista” que hace posible entender y describirla enfermedad. Pero es sobre todo la noción de Derrida de autoinmunidad la que permite pensar la mirada como algo que ya estaba permeada por otro ojo—un extranjero, un extraño, un elemento ominoso que infecta nuestra visión mientras que es, a su vez, su propia condición de posibilidad.
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Social Use of Facial Expressions in Hylobatids
Scheider, Linda; Waller, Bridget M.; Oña, Leonardo; Burrows, Anne M.; Liebal, Katja
2016-01-01
Non-human primates use various communicative means in interactions with others. While primate gestures are commonly considered to be intentionally and flexibly used signals, facial expressions are often referred to as inflexible, automatic expressions of affective internal states. To explore whether and how non-human primates use facial expressions in specific communicative interactions, we studied five species of small apes (gibbons) by employing a newly established Facial Action Coding System for hylobatid species (GibbonFACS). We found that, despite individuals often being in close proximity to each other, in social (as opposed to non-social contexts) the duration of facial expressions was significantly longer when gibbons were facing another individual compared to non-facing situations. Social contexts included grooming, agonistic interactions and play, whereas non-social contexts included resting and self-grooming. Additionally, gibbons used facial expressions while facing another individual more often in social contexts than non-social contexts where facial expressions were produced regardless of the attentional state of the partner. Also, facial expressions were more likely ‘responded to’ by the partner’s facial expressions when facing another individual than non-facing. Taken together, our results indicate that gibbons use their facial expressions differentially depending on the social context and are able to use them in a directed way in communicative interactions with other conspecifics. PMID:26978660
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Internal Flow Structures in Columnar Jointed Basalt from HREPPHÓLAR, Iceland
Mattsson, H. B.; Bosshard, S. A.; Hetenyi, G.; Almqvist, B.; Hirt, A. M.; Caricchi, L.; Caddick, M.
2010-12-01
Columnar jointed basalt from Hrepphólar in southern Iceland display spectacular internal structures when cut. These structures follow the overall orientation of the columns and display semi-circular to circular features when cross-cut. It was previously believed that these internal structures formed as a result of alteration due to circulation of meteoric water within the column-bounding fractures after emplacement. However, new field observations of viscous fingering within the columns and the fact that approximately 80% of the semi-circular features are found within the column whereas the remaining 20% are cut by the column-bounding fractures clearly shows that these internal structures must have formed prior to crack-propagation (and are thus primary features). Here we present the results of textural and petrological analyses through a cross-section of a column, in combination with magnetic susceptibility and anisotropy measurements of the same samples. The variation in textures and geochemistry can be attributed to the presence of diffuse banding caused by variations in the modal proportions of the main phenocryst phases (i.e., plagioclase, clinopyroxene, olivine and titanomagnetite/ilmenite). Orientation of plagioclase laths and titanomagnetite crystals (based on measurements in thin sections and AMS-measurements) are consistent with vertical flow alignment. Nowhere in the column can evidence for downwards flow be found (excluding the possibility of small-scale convection cells generating these features). It is proposed here, that the volume decrease associated with solidification (typically 10-15 vol.% for basaltic systems) and the increasing weight of the overlying crust results in upwelling of partially crystallized material into the centre of the columns. Preliminary numerical modeling indicates that the isotherms within individual columns become steeper with increasing depth in a lava flow (allowing for larger displacement distances). We propose that
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Directory of Open Access Journals (Sweden)
Harun Dıraman
2015-02-01
Full Text Available Bu çalışmada Türkiye’den (2 KKTC, 2 Güneydoğu Anadolu, 3 Akdeniz, 9 Kuzey Ege, 3 İzmir Yarımdası, 16 Güney Ege, 11 Akhisar-Manisa, 4 Marmara ve diğer ülkelerden (1 Ürdün, 1 Filistin, 3 İspanya,1 Portekiz, 2 İtalya, 2 Yunanistan olmak üzere toplam 60 adet ticari natürel zeytinyağı örneği, kemometrik yöntemler (Temel Bileşenler [PCA] Kümeleme [HCA] analizleri yardımıyla triaçilgliserol (TAG bileşenlerine göre sınıflandırılmış ve karakterize edilmişlerdir. Yağ örneklerinin TAG profilleri (ECN 42–ECN 50,LLL ve ana bileşenleri LOO, OOO, POO, PLO ve SOO Avrupa Komisyonu (ABK tarafından onaylanmış Yüksek Basınç Sıvı Kromatografisi ile belirlenmiştir. Türk natürel zeytinyağlarının TAG bileşenlerinin diğer zeytinyağı üreten ülkelerin ürünleri ile benzer olduğu ve bir örnek hariç (Filistin analiz edilen tüm yağ örneklerindeki trilinolein (LLL düzeylerinin, ABK tarafından farklı zeytinyağları için verilen en çok %0.5 düzeyini aşmadığı görülmüştür. Kümeleme analizi (HCA sonuçlarına göre, Türk ve yabancı zeytinyağı örnekleri sırasıyla beş gruba ayrılmıştır. Temel bileşenler analizine (PCA göre, Güney Ege (hâkim çeşit Memecik yağ örneklerinin sınıflandırılmasında LOO/POO, OOO/POO ve OOO düzeylerinin sorumlu olduğu gözlenmiştir. Kuzey Ege (hâkim çeşit Ayvalık örneklerinin ayrımında LOO parametresi büyük rol oynamıştır. Akhisar–Manisa yöresi örnekleri ise ECN48 ve ECN48/ECN46 parametreleri ile karakterize olmuştur. Bu çalışmada Türkiye’den (2 KKTC, 2 Güneydoğu Anadolu, 3 Akdeniz, 9 Kuzey Ege, 3 İzmir Yarımdası, 16 Güney Ege, 11 Akhisar-Manisa, 4 Marmara ve diğer ülkelerden (1 Ürdün, 1 Filistin, 3 İspanya,1 Portekiz, 2 İtalya, 2 Yunanistan olmak üzere toplam 60 adet ticari natürel zeytinyağı örneği, kemometrik yöntemler (Temel Bileşenler [PCA] Kümeleme [HCA] analizleri yardımıyla tria
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Studies on the distribution of gelatinous zooplankton in the ...
African Journals Online (AJOL)
spamer
boundary to the system (Agenbag and Shannon 1988,. Largier and Boyd 2001), it is not considered to have a profound influence on the specific composition of regional zooplankton (Gibbons et al. 1995, Gibbons and Thibault-Botha 2002, but see Barange et al. 1992,. Emanuel et al. 1992). Indeed, it has been suggested.
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Directory of Open Access Journals (Sweden)
Farahnaz Sabet
2015-03-01
Full Text Available Maharloo Lake is one of the most important water ecosystems in Iran, which is nowadays exposed to multiple risks and threats due to poor water management, salt extraction, and heavy metal pollution. In this study, the concentrations of such heavy metals as chromium, copper, zinc, arsenic, cadmium, and lead in both water and salt samples collected from areas in the north and south of the lake were determined by atomic absorption (AA-670G after the samples had been digested. Results showed that metal concentrations in the salt samples taken from both the northern and southern areas had identical mean values in the order of Cr> Cu> As> Cd> Pb. An almost similar pattern was detected in metal concentrations in water samples taken from the same areas but with a slight difference in the way they were ordered (Cr> Cu> As> Pb> Cd. It was found that both water and salt samples collected from the northern areas had higher metal concentrations, except for that of Pb which was slightly lower. Comparison of the mean values of metal concentrations in the Salt Lake and those of Sirjan, Lar, and Firoozabad salt mines revealed that copper, cadmium, and lead had their highest concentrations in the Salt Lake while arsenic and chromium recorded their highest values in samples taken from Lar and Firoozabad salt mines, respectively. Based on these findings, it may be concluded that the increased metal concentrations observed in samples from both northern and southern areas of the lake are due to the sewage and effluents from urban, industrial, and hospital sources in Shiraz disposed into the lake as well as such other human activities as farming in the areas around the lake, especially in the northern stretches. These observations call for preventive measures to avoid further water quality degradation in the area.
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Arao, Tadashi; Okada, Yosuke; Uemura, Fumi; Nishizawa, Shigeru; Tanaka, Yoshiya
A 54-year-old woman was admitted to our hospital for detailed examination of acromegaly because she noticed bilateral hand and finger swelling at the age of 43 and plantar thickening, facial changes and unclear articulation at the age of 49. She had prominent brow ridges, mandibular protrusion, and enlargement of the hands, feet, nasal wings, lips and tongue. Her growth hormone (GH) level was 39.8 ng/ml, insulin-like growth factor-1 (IGF-1) level was 717 ng/ml, GH level was not suppressed (22.9 ng/ml) during a 75-g oral glucose tolerance test (OGTT). Radiography showed cauliflower-like enlargement of the distal phalanx of the fingers, thickening/enlargement of the plantar soft tissues, and increased antero-posterior diameter of the sella turcica. Magnetic resonance imaging showed a mass (21×17 mm) growing towards the right suprasellar region and invading the cavernous sinus. She was diagnosed with acromegaly based on the characteristic physical findings, GH excess, high IGF-1, lack of GH suppression during the 75-g OGTT, and the presence of a pituitary tumor. She was started on octreotide long acting release (Oct-LAR) 20 mg/4w for tumor shrinkage. After three doses, her GH and IGF-1 levels decreased to 2.19 ng/ml (1.69 during the 75-g OGTT) and 205 ng/ml, respectively, meeting cure criteria for acromegaly. In this case, a decrease in GH and IGF-1 levels, tumor shrinkage, and resolution of cavernous sinus invasion allowed the patient to undergo surgery with curative intent (the first-line treatment for acromegaly) without postoperative complications. Thus, preoperative Oct-LAR administration has the potential to improve treatment outcomes of acromegaly.
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Directory of Open Access Journals (Sweden)
Naisy Silva Soares
2013-04-01
Full Text Available Este estudo analisou a influência da taxa de câmbio adotada pelo Brasil e do dólar sobre os preços da borracha natural em moeda brasileira, de janeiro de 2000 a dezembro de 2009. Para isso, fez-se uso do método "shift-share". Considerando os resultados obtidos, observou-se que as variações ocorridas nos preços da borracha natural em moeda brasileira sofreram maior influência das variações do dólar que das variações da taxa de câmbio, mostrando a importância dos preços da borracha natural na Malásia sobre o comportamento dos preços da borracha natural no Brasil.This study analyzed the influence of exchange rate adopted by Brazil and of the dollar over the prices of the Brazilian Natural Rubber in Brazilian currency, from January 2003 to December 2009. Thus, the shift-share method was used. By considering the results achieved in this study, it was found that changes in prices of natural rubber in Brazilian currency were more influenced by the dollar variations than variations in exchange rate, showing the importance of prices in Malasya over the performance of natural rubber prices in Brazil.
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Havuçların Soyulmasının Matematiksel Analizi (İngilizce
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Özlem Aydın
2015-02-01
Full Text Available Bu çalışmada, Beypazarı havuçlarının kabukları, kimyasal yöntem ve buharla soyma yöntemleriyle soyulmuştur. NaOH çözeltisinin konsantrasyonu, sıcaklığı ve daldırma süresinin etkileri araştırılmıştır. Kimyasal yöntemle kabuk soymada optimum süre-sıcaklık-konsantrasyon ilişkileri matematiksel olarak analiz edilmiştir. Deneyler, NaOH konsantrasyonu olarak 2.5, 5.0, 7.5 ve 10.0 g NaOH/kg, sıcaklık olarak 57, 67, 77 ve 87 °C’lerde, %98’den daha fazla soyulma elde edilene kadar uygulanmıştır. 57 °C’de NaOH konsantrasyonu 2.5 g NaOH/kg olan çözelti haricinde diğer sıcaklık ve konsantrasyonlarda tam soyulma gerçekleşmiştir. Optimum soyulma koşulları, 77 °C’de 7.5 g NaOH / kg çözelti konsantrasyonu ve 10.5 dakika daldırma süresi olarak belirlenmiştir. Buharla soyma yönteminde ise doymuş buhar basıncı 130.7 kPa ve sıcaklığı 107 °C olarak uygulanmıştır. Tam soyulma 8.5 dakikada gerçekleşmiştir.
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Enamel renal syndrome: A rare case report
Directory of Open Access Journals (Sweden)
S V Kala Vani
2012-01-01
Full Text Available Enamel renal syndrome is a very rare disorder associating amelogenesis imperfecta with nephrocalcinosis. It is known by various synonyms such as amelogenesis imperfecta nephrocalcinosis syndrome, MacGibbon syndrome, Lubinsky syndrome, and Lubinsky-MacGibbon syndrome. It is characterized by enamel agenesis and medullary nephrocalcinosis. This paper describes enamel renal syndrome in a female patient born in a consanguineous family.
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Kadın Çalışanların Yöneticilere İlişkin Algıları: Bir Alan Çalışması
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İsmail BAKAN
2013-09-01
Full Text Available İşletmelerde yönetim kademesinde yer alan kişilerin ne tür bir liderlik tarzına sahip oldukları çalışanların davranışları ve işletmeye ilişkin tutumları üzerinde önemli etkiye sahiptir. Bu nedenle işletmelerdeki yöneticilerin liderlik tarzlarının çalışanlar açısından nasıl algılandığının tespit edilerek ortaya konulması yöneticiler tarafından başarılı bir yönetim sergilenmesinde yol gösterici olacaktır. Literatürde liderlik tarzlarına ilişkin çeşitli ayrımlar bulunmakta olup bu çalışmada öncelikle liderlik kavramı ve liderlik tarzlarına ilişkin genel bilgiler verilerek, daha sonra otokratik, demokratik ve serbest bırakıcı liderlik tarzları açıklanacaktır. Çalışmanın ikinci bölümünde ise Kahramanmaraş’ta lokomotif sektör olarak görülen tekstil sektöründe, kadın çalışanların çalıştıkları işletmelerde bulunan yöneticilerin, liderlik tarzlarına ilişkin algılarını ölçmek amacıyla yapılan bir alan araştırmasına yer verilecektir.
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KALKAN ERDOĞAN, Meryem
2017-01-01
Bu çalışmada, tekstil sanayiinde önemli sentetik liflerden olan poli(etilen teraftalat) (PET) esaslı polyester (PES) kumaşların, indigo boyarmaddesi ile pamuklu denim (kot) kumaşlara benzer şekilde yüzeysel ve kesintisiz olarak soğukta boyanabilmesi amacıyla, poli(vinil alkol) (PVA) ve farklı bileşimlerde sentezlenen modifiye PVA (M-PVA) polimerlerini kullanarak fiziksel ve kimyasal yöntemler ile modifikasyonu gerçekleştirildi. M-PVA polimerleri, PVA varlığında glisidil metakrilat (G...
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Directory of Open Access Journals (Sweden)
Işıl Ergin
2011-09-01
Full Text Available Genetiği değiştirilmiş gıdalar modern biyoteknolojinin gıda üretimine uygulanan şeklidir. Gittikçe yaygınlaşan kullanım alanı, bu gıdaları toplum sağlığı açısından dikkat çekici bir noktaya taşımıştır. GDO (Genetiği Değiştirilmiş Organizma’ların sağlık etkileri konusunda güvenilir olduğuna dair görüş bildirenlerin yanı sıra, insan sağlığını tehdit ettiği görüşünü dile getiren araştırmacılar da vardır. GDO ların sağlığa zararlı olup olmadığına dair saptamaları yapmak ise beslenme epidemiyolojisi alanının zorlukları, risk değerlendirme sürecindeki sorunlar, hayvan deneylerindeki sınırlılıklar ve bilginin tarafsızlığına dair kuşkular nedeniyle zorlaşmaktadır. Tüm bu bilimsel açmazlara rağmen alerjik ve toksik etkilere dair ipuçlarının artması, antibiotik direnci olasılığının bilimsel kurumlarda yarattığı endişe, besin değerlerindeki değişmenin ve gen transferi olasılığının yayınlarda yer alması; görünür hale gelen sağlık etkilerini göstermektedir. Karşılaştırılabilirliği mümkün kılacak standart tasarıma ve ileri analiz yöntemlerine ihtiyaç vardır. Uzun erimdeki etkilerini ortaya koyacak ve iyi planlanmış kohort araştırmalarının gerekliliği mutlaktır. Zararsız olduklarını bilimsel bir özgüvenle söylemek için ise erkendir. Risklerin henüz net olarak ortaya konamaması, olmadığı anlamına gelmemektedir. Risklerin neler olduğunu kesin olarak ortaya koyacak araçlarımız henüz yeterli değildir. Sürece ihtiyat ilkesi doğrultusunda yaklaşmak gerekmektedir.Anahtar Kelimeler: Genetiği değiştirilmiş gıdalar, beslenme epidemiyolojisi, riskGenetically modified organisms: Why is it difficult to prove health hazards? Problems and clues about riskGenetically modified foods are in the area where biotechnology is applied to foods. Their common use has driven them to a substantially important position in
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Special polynomials associated with the fourth order analogue to the Painleve equations
International Nuclear Information System (INIS)
Kudryashov, Nikolai A.; Demina, Maria V.
2007-01-01
Rational solutions of the fourth order analogue to the Painleve equations are classified. Special polynomials associated with the rational solutions are introduced. The structure of the polynomials is found. Formulae for their coefficients and degrees are derived. It is shown that special solutions of the Fordy-Gibbons, the Caudrey-Dodd-Gibbon and the Kaup-Kupershmidt equations can be expressed through solutions of the equation studied
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Oliveira, Arlete Correa de
2011-01-01
Este trabalho questiona a lei, sob a ótica da subjetividade, no universo de crianças e jovens abrigados na Casa-Lar Bela Vista, Vitória, Espírito Santo. Sua temática central é a lei da proibição do incesto (EEP) e os complexos familiares (Lacan) cujos pressupostos teóricos orientam esta pesquisa e permitem explicitar a presença dessa lei na subjetividade humana e no laço social. Dentro desse questionamento, surge a importância da interface entre a assistência social e a explici...
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State of Washington Aquatic Plant Management Program. Supplement
1991-03-01
which are sticky fluids such as inverting oils and polymers, or fibers, which enhance clinging to submersed vegetation (Getsinger and Westerdahl , 1988...primarily by photolysis, by biodegradation, and least significantly by volatilization ( Westerdahl and Getsinger 1988). Thus, there is no reason for... Westerdahl . 1988. Hiscellaneous-Paper A-88-1, Waterways Experimental Station, COE, Vicksburg, MS, 24 pp. Gibbons, M.V., H.L. Gibbons, and R. Pine:. 1987. 1986
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Empirical Evaluation of a Decision-Analytic Aid.
1980-05-01
Morris, Smallwood , Lansford, and Gibbons (1980) state: "In the traditional paradigm, the decision-maker must decide to accept or reject the model. If he... Smallwood , R. D., Langford, R. K., & Gibbons, R. S. Analytic Procedures for Evaluating Decision Aids. Applied Decision Analysis, Inc. (Menlo Park, CA...Menlo Park, CA 94025 Department of Psychology University of Oklahoma Dr. Jesse Orlansky 455 West Lindsey Institute for Defense Analyses Norman , OK 73069
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Directory of Open Access Journals (Sweden)
İnci Önal
2008-10-01
Full Text Available [Turkish abstract] Araştırmanın amacı, Türkiye’de gazetecilerin bilgi gereksinimlerini ve arama davranışlarını ortaya çıkarmaktır. Ocak 2007 ile Haziran 2008 tarihlerinde gerçekleştirilen bu araştırmada, Türkçe olarak yayınlanan 31 ulusal günlük gazetede görev yapan 217 gazetecinin özellikleri, bilgi gereksinimleri, ilgileri, bilgi kaynaklarını ve bilgi merkezlerini kullanma amaçları saptanmıştır. Gazetecilerin araştırma alanlarının başında haberin yazımı ile ilgili bilgiler geldiğinden, bu doğrultuda geniş kapsamlı, güncel ve orijinal bilgiye en kısa zamanda ulaşmak istenmektedir. Yapısal değişimler, ekonomik güçlükler ve enformasyon teknolojisinin kullanımı, gazetecilerin bilgi gereksinimlerini ve bilgi arama davranışlarını değiştirmiştir. Gazetecilerin kütüphanelerde ve arşivlerde karşılaştıkları bilgi erişim engellerinin başında bilgiye-belgeye hemen erişememe, aranılan kaynağı bulamama, bilgi hizmetlerine yabancılık, öz bilgiye erişememe gibi sorunlar gelmektedir. Çalışmanın sonunda mevcut durumu iyileştirmek için bazı öneriler sunulmuştur. Böylece gelecekte bilgi erişimi kolaylaştıran sistemlerin hayata geçirilmesi beklenmektedir. [English abstract]The purpose of this research was to investigate the information needs and information seeking behaviour of working journalists in Turkey. It investigated characteristics, information needs, interests, sources and purposes, libraries used and services required by 217 journalists in 31 national Turkish daily newspapers, during the period among January 2007 and June 2008 by means of a conducted survey. Journalists have a need for large volumes of very current and authoritative information, and they felt urged to ask the required information very quickly. Throughout the time it seems that shifts in newspaper coverage, the changing economic conditions, and the information flood provided through the new
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First operation and performance of a 200 lt double phase LAr LEM-TPC with a 40x76 $\\cm^2$ readout
Badertscher, A; Degunda, U; Epprecht, L; Gendotti, A; Horikawa, S; Knecht, L; Natterer, D Lussi G; Nguyen, K; Resnati, F; Rubbia, A; Viant, T
2013-01-01
In this paper we describe the design, construction, and operation of a first large area double-phase liquid argon Large Electron Multiplier Time Projection Chamber (LAr LEM-TPC). The detector has a maximum drift length of 60 cm and the readout consists of a $40\\times 76$ cm$^2$ LEM and 2D projective anode to multiply and collect drifting charges. Scintillation light is detected by means of cryogenic PMTs positioned below the cathode. To record both charge and light signals, we have developed a compact acquisition system, which is scalable up to ton-scale detectors with thousands of charge readout channels. The acquisition system, as well as the design and the performance of custom-made charge sensitive preamplifiers, are described. The complete experimental setup has been operated for a first time during a period of four weeks at CERN in the cryostat of the ArDM experiment, which was equipped with liquid and gas argon purification systems. The detector, exposed to cosmic rays, recorded events with a single-ch...
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Phase II trial of SOM230 (pasireotide LAR in patients with unresectable hepatocellular carcinoma
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Feun LG
2018-01-01
Full Text Available Lynn G Feun,¹ Medhi Wangpaichitr,² Ying-Ying Li,¹ Deukwoo Kwon,³ Stephen P Richman,¹ Peter J Hosein,¹ Niramol Savaraj¹,² ¹Department of Medicine, Medical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, ²Department of Surgery, Miami VA Healthcare System, Research Service, ³Biostatistics and Bioinformatics Core, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA Background: A phase II trial of pasireotide was performed to assess its efficacy and safety in advanced or metastatic hepatocellular carcinoma (HCC.Patients and methods: Patients with advanced HCC and Child–Pugh score ≤7 received pasireotide LAR 60 mg intramuscularly every 28 days. Primary endpoint was disease control rate. Secondary endpoints were time to tumor progression, response rate, treatment-related adverse events, and overall survival. Serum insulin growth factor-1 was measured before and after pasireotide.Results: Twenty patients were treated and evaluable. Eighteen patients (90% had prior therapy; 16 patients (80% had multiple therapies. Median age was 65, 75% had Barcelona Clinic Liver Cancer stage C, and 55% had metastatic disease. The main toxicity was hyperglycemia. Rare adverse effects included reversible grade 4 elevation in alanina transaminase/aspartate transaminase in one patient. The best response was stable disease in 9 patients (45%. Median time to tumor progression for the 20 patients was 3 months, and median survival was 9 months.Conclusion: Pasireotide had limited clinical benefit as second-line or third-line treatment in patients with advanced or metastatic HCC. Low baseline insulin growth factor-1 level may be indicative when SOM230 treatment may be ineffective, and decreasing levels after treatment may be indicative of disease control. Keywords: pasireotide, hepatocellular carcinoma, insulin growth factor-1
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Terekeme (Karapapak Türkleri ve Mânileri (Bayatıları/Mahnıları: Muş-Bulanık Çevresi
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MUHAMMET KEMALOĞLU
2013-03-01
Full Text Available AbstractManis, which are called with different names in the geography of Anatolia, show similarities in terms of form and content in general. Mani read within a particular tradition also reflects poetry taste of the Turkish people ideally. This study benefits from the data of field research that we have done. Mani and the tradition of reading Mani which has been got through compilation in the field, transmitted from generation to generation, which has specific rules and reflects the mentality, love, longing, feeling, and behavior of local people and culture of the region are going to form the main part of the study. In addition to this, characteristics of Terekeme (Karapapak Turks’ dialect are also dwelled on.ÖzetAnadolu coğrafyasında farklı isimlerle zikredilen mâniler, şekil ve muhteva açısından genel olarak benzerlikler göstermektedir. Belirli bir gelenek dâhilinde söylenen mâniler, Türk halkının şiir zevkini de en güzel şekilde aksettirmektedir. Bu çalışmada yapmış olduğumuz saha araştırmasının verilerinden yararlanılacaktır. Çalışmanın esas bölümünü; sahada derlemeler yoluyla elde edilmiş, kuşaktan kuşağa aktarılan, belirli kuralları olan, yöre insanının; düşünce yapısını, sevdalarını, özlemlerini, duygu ve davranışlarını, yörenin kültürünü yansıtan maniler ve mani anlatma geleneği oluşturmaktadır. Bunun yanı sıra Terekeme (Karapapak Türklerinin ağız özellikleri üzerinde de durulmuştur.Les turcs de Terekeme (Karapapak et leurs qutrains (region de Muş-BulanıkRésuméLes manies appelées par des noms différents en Anatolie,présentent des ressemblances en terme de forme et de contenu. Les manies, qui se disent dans une tradition particulière, reflètent aussi le plus bel exemple de la poésie du peuple turc. Dans cette étude, nous allons utiliser les données de notre recherche de terrain. La partie fondamentale du travail consiste en manies et la tradition
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Ing-Marie Gren
2015-10-01
Full Text Available We calculate values of forest carbon sequestration and nutrient recycling applying the replacement cost method. The value is then determined as the savings in costs by the replacement of more expensive abatement measures with these ecosystem services in cost-effective climate and nutrient programs. To this end, a dynamic optimization model is constructed, which accounts for uncertainty in sequestration. It is applied to the Stockholm-Mälar region in southeast Sweden where the EU 2050 climate policy for carbon emissions and the Baltic Sea action plan for nutrient discharges are applied. The results show that the value of carbon and nutrient sequestration can correspond to approximately 0.5% of the region’s gross domestic product, or 40% of the value of productive forest. The largest part of this value is attributed to carbon sequestration because of the relative stringency in targets and expensive alternative abatement measures. However, sequestration is uncertain because of stochastic weather conditions, and when society has a large risk aversion for not attaining climate and nutrient targets, the values of the forest carbon and nutrient sequestration can approach zero.
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Görün ARUN
2010-01-01
Full Text Available Many settled areas in Turkey and across the globe suffer economical and social losses resulting from natural disasters such as earthquakes, floods, hurricanes and landslides. In this study, a vulnerability assessment model has been developed for earthquake prone areas in Turkey. The vulnerability assessment model includes ground factors, a building’s physical conditions, building evacuation and social (demographic and socioeconomic aspects of the settlement. The ground vulnerability factor is calculated using factors such as the earthquake zone, soil classification, land sliding and liquefaction threats. The physical vulnerability factor depends on the structural and non-structural threats of the building; the building evacuation vulnerability factor includes the position and structural system of the staircase, the width and natural illumination of the evacuation route, the size and opening of the building exit doors to the street and the distance of the building to the closest open area. The social vulnerability factor considers the age group, gender, family type, education, ownership, income etc of the building users. This vulnerability assessment model is applied to a case study - that of the Avcılar district of Istanbul. Forty different reinforced concrete residential buildings (349 apartments of 1225 people are assessed using the develop checklist. In order to evaluate the checklist and to assess the importance (relevance of vulnerability factors, a questionnaire is forwarded to various related professional groups (architecture, urban planning and civil engineering. The results of the questionnaire are examined using SPSS software with factor analysis. According to the results, most of the samples in the case study area can be classified as high vulnerable.
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Army Sustainment. Volume 47, Number 6. November-December 2015
2015-11-01
SP TBD AWT/ AVN T: SPT Convoy GOLD / 13B SP 1315 / 1415 T: SPT Convoy Turani SP 1115 T: SPT Convoy GOLD / 13B SP 1315 / 1415 T: SPT Convoy Turani SP...white Ford observed). Legend A/DACG = Arrival/departure airfield control group AWT/ AVN = Air weapons teams/aviation BSA = Brigade support area...Tech AED Engineer AMCOM LAR AMCOM LAR AMCOM LAR AMCOM UAS LAR PM UAS Lead TACOM LAR AMCOM LAR AMCOM LAR CECOM AVN LAR AMCOM LAR PM UAS CECOM AVN LAR
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Hüseyin MUSMAL
2013-09-01
Full Text Available This study consist of tombstones which are from ottoman era inthe graveyard of Fasillar village in district beyşehir of konya. In thisstudy 28 headstones and 19 footstones which were written by ottomanturkish with arabic letter were ascertained and analized in terms ofhistorical and art history. In this study all tombstones have beendiscussed separetely and a general evaluationhas been done via thesetombstone. But while we were writting the text part, firstly we made ageneral evaluation and at the end of this study tombstones that wereinvestigated, handled individually (one by one as a catalogue. Villagefasillar which is bounded up Beyşehir district of konya was establishedtwo great hills that consist of rock. The region in which includedFasillar falso, had a great importance in Hittite Empire era. FasillarMonument which belongs to Hittite era and was known by historianand archaeologist, and researching seval speciality of this region.Having the processable stone resources of the region provideed tooccour a custom on stonework. When the qualities, quantities, typesand features are investigated, it iş understood that inhabitants of villageFasillar sustainedthis custom throughout 20th century. The shapes andornamentations of tombstones, and expressions and templates showthat inhabitants have different ial skils from other settlements as socialeconomical and cultural. Konya İli Beyşehir İlçesi Fasıllar Köyü Mezarlığı’nda bulunan Osmanlı dönemine ait mezar taşları bu çalışmanın inceleme konusunu oluşturmaktadır. Çalışmamızda Fasıllar Köyü mezarlığında tespit edilen Arap harfleri ile Osmanlı Türkçesi kullanılarak yazılmış 28 baş taşı ve 19 ayak taşı, tarih ve sanat tarihi ölçütlerine göre incelenmektedir. Çalışmada her bir mezar taşı ayrı ayrı ele alınmış ve bu taşlar üzerinden genel bir değerlendirme yapılmıştır. Ancak çalışmamızın metin bölümü oluşturulurken,
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Lactococcus lactis Subsp. Lactis Suşlarında Yüksek Sıklıkta Konjugal Transfer Sistemlerinin Analizi
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Çağla Tükel
2015-02-01
Full Text Available Bu çalışmada L. lactis subsp. lactis suşlarında laktoz fermentasyonu özelliğini kodlayan altı farklı plazmidin yüksek sıklıkta konjugal aktarım yeteneği araştırıldı. Bu plazmidlerin konjugal transfer sıklıkları; iki seks faktörünün interaksiyonuna bağlı olarak (Clu ve Agg, Clu-/Agg-, Agg+ x Clu-/Agg+, Agg- ya da Clu+/Agg- x Clu-/Agg- konjugasyon eşleri için 1.5x10-5–1.0x10-7 ve Clu+/Agg- x Clu-/Agg+ konjugasyon eşleri için 7.1x10-2-2.7x10-3 oranlarında değişim gösterdi. Laktoz plazmidlerinin stabiliteleri ise; doğal suşlarda %82-96, MG1390 alıcı suşu için tanımlanan konjugantlarda %77-98 ve MCL8060 alıcı suşu için tanımlanan konjugantlarda ise %44-67 arasında saptandı.
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Ebru Albayrak Özer
2017-12-01
Full Text Available The aim of the research is to examine the relationship between students’ personality types (extraversion, introversion, openness to experience and closeness to experience and their preference of various Web 2.0 tools to describe how these tools can be utilized in educational settings. Specifically, the study investigates which of the Web 2.0 tools are preferred and best meet the need of the different personality types. The participants included 22 students who were in their third year in the Department of Computer Education and Instructional Technologies of the Sakarya University during the semester of Fall 2014. Five of these students were introvert, five were extrovert, six of them were open to experience and six were closed to experience. These students were selected with the purposive sampling method out of 30 students who were subjected to the Adjective-Based Personality Test. According to the results, students’ preferences of using social media differed by their personality types. Facebook, Twitter and Instagram were the most popular tools among students. Results from the study also indicate that it is critical to utilize the most preferable and practical web 2.0 tools so that students with different personality traits could adapt to the class. Furthermore, measures need to be taken to prevent possible negative consequences of using these tools. [Araştırmada üniversite öğrencilerinin yeniliğe açıklık-kapalılık ve dışadönüklük-içedönüklükleri ile web 2.0 kullanım tercihleri arasındaki ilişki incelenerek eğitimde hangi araçların kullanımının hangi tip öğrencilere daha çok hitap ettiği belirlenmeye çalışılmış ve bu araçların eğitimde nasıl kullanılabileceği tartışılmıştır. Araştırmanın çalışma grubunu 2014-2015 güz yarıyılında Sakarya Üniversitesi Bilgisayar ve Öğretim Teknolojileri Eğitimi Bölümü’nde 3. Sınıfta eğitim gören 22 öğrenci oluşturmaktadır. Bu
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Baki ŞAHİN
2013-04-01
Full Text Available Bu araştırmanın amacı Muğla Üniversitesi Eğitim Fakültesinde okuyan öğretmen adaylarının “Matematik Öğretmeni”, Matematik” ve “Matematik” dersi kavramlarına yönelik algılarını oluşturan metaforları belirlemektir. Araştırmaya anket maddelerinin oluşturulma sürecinde iki branştan toplam 76 ve oluşturulan anket maddelerini cevaplandırmak için de dokuz farklı branştan toplam 1185 öğretmen adayı katılmıştır. Araştırmada nitel ve nicel ölçme araçları kullanılmıştır. Elde edilen sonuçlara göre üç kavramda da öğrencilerin algılarının branşlara göre farklılaştığı görülmüştür. “Matematik Öğretmeni” kavramı en çok “Bilgili” ve “Otoriter” metaforlarıyla algılanmaktadır. “Matematik Öğretmeni” kavramı, ilköğretim matematik öğretmeni ve lise matematik öğretmeni olarak iki farklı şekilde düşünüldüğünde, algılanan metaforların da değiştiği fark edilmiştir. “Matematik” kavramı “Zeka”, “Zevkli”, “Gerekli”, “Yetenek”, “Zor”, “Başarı” metaforlarıyla ilişkilendirilmiştir. En az tercih edilen metaforlar ise, “Gereksiz”, “Kolay” ve “Otorite” olmuştur. Matematik Derslerini algılama metaforları açısından anabilim dalları öğrencilerinin üç gruba ayrıldığını göstermektedir. Fen, Sınıf ve Okul Öncesi Öğretmenli öğrencileri “Matematik Dersi” kavramını olumlu metaforlarla ilişkilendirmekte; Almanca, İngilizce ve Türkçe Öğretmenliği öğrencileri kısmen olumlu, özellikle lise yıllarında olumsuz algı oluştururken; Müzik, Resim ve Sosyal Bilgiler Öğretmenliği öğrencileri en olumsuz, özellikle de lise yıllarında matematik dersini olumsuz algılamışlardır.
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Peters, Ralph
2008-01-01
Lars Krogmann wurde 1976 geboren in Norderstedt bei Hamburg. Schon früh entwickelte er eine Leidenschaft für Insekten, insbesondere für Tagschmetterlinge. Der Legende nach soll er bereits als Heranwachsender stets „Entomologe“ als Berufsziel ausgegeben haben. Folgerichtig begann er nach dem Abitur und Zivildienst im Jahr 1996 ein Studium der Biologie in Hamburg. Im Studium belegte er jeden Kurs, der entomologische Inhalte hatte, und er arbeitete als studentische Hilfskraft in der Entomologisc...
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Farklı Eğim Açılarındaki Fotovoltaik Panellerin Elektriksel Ölçümlerinin Raspberry Pi ile İzlenmesi
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Harun ÖZBAY
2016-03-01
Full Text Available Güneş enerjisinden elektrik enerjisi elde etmek için fotovoltaik (FV paneller kullanılmaktadır. FV panellerden elde edilen enerji, panellerin kurulduğu coğrafi konuma, mevsimsel değişimlere ve çevre koşullarına göre sürekli olarak değişiklik göstermektedir. Dolayısıyla FV panellerden maksimum güç elde edilmesi amacıyla panellerin optimum eğim açısının aylık, mevsimsel ve yıllık olarak değiştirilmesi gerekir. Bu çalışmada, farklı açılarda yerleştirilen FV paneller ile Bilecik ilinde güneş enerjisinden elde edilecek maksimum gücün hangi eğim açılarında gerçekleştiğinin tespiti için verilerin toplanması, kayıt altına alınması ve analiz çalışmaları Raspberry Pi (RPi üzerine kurulu web sunucu aracılığı ile gerçekleştirilmiştir. Bu amaç doğrultusunda FV panellerin gerilimleri gün boyunca ölçülmektedir. Ölçülen veriler analog-dijital dönüştürücü (mikrodenetleyici ile sayısal bilgiye çevrilmektedir. RPi ile sayısal bilgilerin her 10 dakikada bir ortalaması alınarak kendi hafıza ortamında saklama işlemi gerçekleştirilmektedir. Aynı zamanda RPi’ye kurulan Linux temelli Raspbian işletim sisteminde oluşturulan betik yardımıyla ve web ara yüzünden aynalama işlemi yapılarak verilerin bilgisayar ortamına kaydedilmesi ile yedekleme işlemi gerçekleştirilmektedir. Farklı eğim açılarındaki FV panellerden elde edilen elektriksel ölçümler RPi üzerine kurulu web sunucu aracılığıyla günün her saatinde canlı olarak izlenebilmektedir. Ayrıca elektriksel veriler aylık ve yıllık olarak tarih ve zaman bilgileri ile kayıt altına alınmaktadır. Geliştirilen sistemin kullanıcı ara yüzüne http://solar.bilecik.edu.tr adresinden ulaşılabilmektedir.
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Mehmet Nuri GÖMLEKSİZ
2013-09-01
ürecinin yanı sıra, dil öğrenmeye ilişkin tutum ve algıların da önemli bir yeri bulunmaktadır. Bireyin yabancı dil öğrenmeye yönelik tutum ve algılarının olumlu olması yabancı dil öğrenme sürecini olumlu yönde etkileyebildiği gibi olumsuz tutum ve algılar da öğrenme sürecini olumsuz etkilemektedir. Bu çalışmanın amacı öğretmen adaylarının yabancı dile ilişkin algılarını metaforlar yoluyla belirlemektir. Çalışma 2012-2013 eğitim ö��retim yılında Fırat Üniversitesi Eğitim Fakültesi’nde öğrenim gören öğretmen adayları üzerinde yürütülmüştür. Araştırmaya katılmada gönüllülük dikkate alınmıştır. Araştırma kapsamına 289’u kadın 253’ü de erkek olmak üzere toplam 542 öğretmen adayı alınmıştır. Veriler “Yabancı dil……e/a benzer; çünkü…………….” biçiminde eksik bırakılmış bir cümlenin bulunduğu formlarla toplanmıştır. Metafor formları katılımcılara sınıflarında elden dağıtılmıştır. Öğretmen adaylarından akıllarına gelen ilk metaforu yazmaları istenmiştir. Metafor formunu tamamladıktan sonra yabancı dile ilişkin geliştirdikleri metaforun gerekçesini yazmaları istenmiştir. Bunun için bir ders saati kullanılmış ve formlar aynı yolla toplanmıştır. Verilerin analizinde içerik analizi kullanılmıştır. Araştırma sonucunda yabancı dil kavramına ilişkin 54 metaforun geliştirildiği sekiz ayrı kavramsal kategori elde edilmiştir. Bunlar; gelecek, gereklilik, güç, keyif, seyahat, ümitsizlik, zorlukile sömürgecilik biçiminde isimlendirilmiştir. Araştırma sonuçlarına bağlı olarak yabancı dil öğrenimi için çeşitli önerilerde bulunulmaktadır.
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Filiz ÇOLAK
2013-07-01
OttomanState will be analyzed based on the data from foreign policy statistics. Osmanlı Devleti’nin son on yılı birbirini takip eden savaşlarla geçmiştir. Bu son on yıl bir Türk-İtalyan savaşı olan Trablusgarp Savaşı ile başlar, Balkan Savaşları, Dünya Savaşı ve Milli Mücadele hareketi ile sona ermiştir. Bu savaşlar devletin hem siyasi itibarını hem de ekonomik durumunu derinden sarsmış ve sonunda Osmanlı Devleti’nin tarihteki yerini almasıyla sonuçlanmıştır.Trablusgarp ve Balkan Savaşları, meydana geldikleri süreç içerisinde Osmanlı Devleti’nin hem harici siyasetini hem de iktisadini hayatını derinden etkilemiştir. İtalya’nın 1911 yılında Trablusgarp topraklarını işgal etmesi ile başlayan Türk-İtalyan Savaşı, Osmanlı-İtalyan ticari ilişkileri üzerinde kısa bir süre de olsa gerginliğin oluşmasına neden olmuştur. Daha önce, 1908’de, Avusturya-Macaristan’ın Bosna-Hersek’i işgali üzerine Avusturya mallarına yapılan boykot örneği 1911 yılında İtalyan mallarına da uygulanmaya başlamıştır. Boykot fikri, ilk olarak Hükümetin İtalya’ya savaş ilan etme konusunda gecikmesi nedeniyle basında ortaya çıkmıştır. Ancak Babıâli, kapitülasyonlar nedeniyle İtalyan mallarının ülkeye girişini önleyemediği için ilk önlem olarak İtalyan mallarından alınan gümrük vergilerini yükseltme yoluna gitmiştir. Bu uygulamaya 1912’deki barış antlaşmasına kadar devam edilmiştir.1912 yılında Osmanlı Devleti, liderliğini Bulgaristan’ın yaptığı Balkan devletlerinin aralarında oluşturdukları ittifakla (Bulgaristan-Sırbistan-Yunanistan-Karadağ bir oldu-bitti karşısında kendisini savaşın içinde bulmuştur. Babıâli, hiçbir seferberlik hazırlığı yapamadan girdiği bu savaşta, bir yandan ordunun ihtiyaçlarını karşılamaya çalışırken diğer yandan da bu devletlerle ticari ilişkilerini yeniden gözden geçirerek bir takım önlemler almaya
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Mirna Bastos Marques
2006-12-01
Full Text Available JUSTIFICATIVA E OBJETIVOS: Durante uma craniotomia em que se realiza o teste de Afasia de Aachen com o paciente acordado e cooperativo, é necessário o uso da técnica anestésica "dormindo-acordado-dormindo". O objetivo deste relato de caso foi descrever a técnica anestésica utilizada em paciente com sinais de via aérea difícil. RELATO DO CASO: Descreveu-se o caso de um paciente submetido à ressecção de um tumor no lobo temporal esquerdo, no giro de Wernicke, com sinais clínicos de via aérea difícil. Foi utilizada a técnica "dormindo-acordado-dormindo", com infusão contínua de propofol e remifentanil. A via aérea foi mantida com o uso da máscara laríngea, por abordagem lateral. CONCLUSÕES: A técnica utilizada foi eficaz para a obtenção de um paciente acordado e cooperativo no intra-operatório, tendo sido assegurada permeabilidade da via aérea com o uso da máscara laríngea. A inserção desse dispositivo por abordagem lateral é de especial interesse por se tratar de um paciente com possível dificuldade de acesso à via aérea, em procedimento cirúrgico em que era necessário evitar deslocamento do paciente e contaminação do campo cirúrgico.JUSTIFICATIVA Y OBJETIVOS: Durante una craniotomía en que se realiza la prueba de Afasia de Aachen con el paciente despierto y cooperativo, se necesita el uso de la técnica anestésica "durmiendo-despierto-durmiendo". El objetivo de este relato de caso fue el de describir la técnica anestésica utilizada en paciente con señales de vía aérea difícil. RELATO DEL CASO: Se ha descrito el caso de un paciente sometido a la resección de un tumor en el lobo temporal izquierdo, en el giro de Wernicke, con señales clínicos de vía aérea difícil. Fue utilizada la técnica "durmiendo-despierto-durmiendo", con infusión continua de propofol y remifentanil. La vía aérea se mantuvo con el uso de la máscara laríngea, a través de abordaje lateral. CONCLUSIONES: La t
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Directory of Open Access Journals (Sweden)
Doç.Dr. Fatih Başaran
2008-01-01
Full Text Available Trol ve uzatma ağları ile İzmir körfezinden yakalanan dil (Solea solea balığının yaşama yüzdesi; kültür şartlarına adaptasyonu ve beslenme davranışı. Bu araştırmada, doğal ortamdan yakalanan dil balığının (Solea solea, kültür şartlarına adaptasyonu ve beslenme davranışı incelenmiştir. Dil balıkları, 2007 Mart-Nisan döneminde, İzmir Körfezi’nden trol ve uzatma ağlarıyla yakalanmıştır. 270 adet dil balığının ön adaptasyonu sırasında, ilk beş gün boyunca, karanlık ortamda antibiyotik (100 ppm fruzolidon ilavesi, 60 dak/gün uygulaması gerçekleştirilmiştir. Kültür şartlarında ilk besleme için, kalamar (Loligo vulgaris, boru kurdu (Diopatra neopolitana, kara midye (Mytilus galloprovincialis, sülünes (Solen marginatus, istiridye (Ostrea edulis, japon şapkası (Patella spp., deniz salyangozu (Monodonta turbinata ve taze sardalya (Sardina pilchardus kullanılmıştır. Dil balıkları 0-2 gün içinde beslenmeye başlamıştır ve boru kurdu, en çok tercih ettikleri tür olmuştur. Bir aylık adaptasyon dönemi sonunda, uzatma ağlarıyla yakalanan dil balıklarının yaşama oranının (%58, trol ile yakalananların yaşama oranından (%29 önemli düzeyde yüksek bulunmuştur (p
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ÖZDEMİR, Agah Oktay; TUTAK, Mustafa
2013-01-01
Yüksek yaş haslıkları, geniş renk paletleri ve çok sayıdaki boyama yöntemine uygunluk gibi avantajları nedeniyle reaktif boyarmaddeler, selülozik esaslı kumaşların boyanmasında önemli bir boyarmadde sınıfını oluşturmaktadırlar. Reaktif boyalar ve pamuk lifleri sulu ortamda çözünerek anyonik karaktere sahip olurlar. Boya ve pamuk lifi arasındaki negatif yükü ortadan kaldırıp boyarmaddelerin lifler tarafından çekilmesini sağlamak için boya banyosuna tuz eklenir. Bu çalışmada ticari olarak kulla...
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Eru, Oya
2013-01-01
Gelişen teknolojik koşullar iletişim teknolojilerinde de bir takım yeniliklerin yaşanmasını sağlamıştır. Günümüzde mobil teknolojiler ve mobil iletişim insanlar için vazgeçilmez hale gelmiştir. Özellikle İnternet-mobil cihaz birlikteliği, mobil teknolojilerin daha da gelişmesini ve sadece iletişim odaklılıktan çıkarak farklı boyutlarda kullanılmaya başlamasına neden olmuştur. Mobil cihazların her zaman kullanıcıları ile bir arada olduğu ve kimi tüketicilerin birden fazla mobil araca sahip ...
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Directory of Open Access Journals (Sweden)
Paulo Augusto de Lima Pontes
2005-12-01
Full Text Available A videoquimografia é considerada a mais recente tecnologia na semiologia avançada da laringe. A videoquimografia utiliza-se de tecnologia digital para a análise ultra-rápida da vibração das pregas vocais. A imagem apresentada é a referência de uma única linha, representando um estreito segmento horizontal da imagem laríngea. A videoquimografia avalia todos os tipos de irregularidades de vibração, identifica pequenas assimetrias esquerda-direita, diferenças no quociente de abertura ao longo das pregas vocais, propagação lateral da onda mucosa e movimentação das margens superior e inferior da onda de mucosa das pregas vocais. O objetivo do presente estudo foi verificar a correspondência das imagens obtidas na videoquimografia, com variação do ângulo de exposição da laringe em relação ao telescópio. Foram analisados três indivíduos do sexo feminino, sem queixa vocal. As imagens videoquimográficas foram registradas com o telescópio laríngeo de 90o posicionado na linha média, perpendicular à glote - zero grau, durante a emissão de uma vogal sustentada "é", em freqüência e intensidade habituais. O procedimento foi repetido mais duas vezes, porém com rotação de quinze graus do telescópio, no sentido horário, deslocando-se o laringoscópio à direita da linha média do paciente e, no sentido anti-horário, à esquerda. Os resultados obtidos indicaram diferenças evidentes nas imagens obtidas, o que demanda uma padronização da exposição laríngea para a interpretação da videoquimografia.Videokymography is a new high-speed imaging technique to investigate vocal fold vibration. The system has been considered useful in the analysis of irregular signals, making it possible to observe left-right asymmetries, open quotient, propagation of mucosal waves, and movement of the upper and lower margins. The aim of the present study was to verify the correspondence of the videokymographic images with larynx exposition
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Directory of Open Access Journals (Sweden)
Muhittin ADIYAMAN
2012-12-01
Full Text Available Bu çalışma 4077 Sayılı Tüketicinin Korunması Hakkında Kanun’la hukuk sistemimize kazandırılan Tüketici Sorunları Hakem Heyetlerinin işleyişi, şikâyetlerin alınma ve değerlendirme sürecine dair 358.566 nüfuslu Odunpazarı ilçesinde tüketici sorunlarına üretilen çözümlerin boyutu ve tüketici davranışlarını sunmayı amaçlayan bir uygulama örneğidir. Çalışmamız; Tüketici Sorunları Hakem Heyeti Yönetmeliğinin 25. Maddesi gereği dörder aylık dönemler hâlinde hazırlanan Eskişehir Odunpazarı Tüketici Sorunları Hakem Heyeti’nin 2009-2012 yılları arasındaki faaliyet raporlarında belirtilen müracaat sayıları, tüketicinin lehine ve aleyhine olarak sonuçlanan karar sayıları ve şikâyetlerin türünü kapsamaktadır. Tüketici Sorunları Hakem Heyetleri aynı yönetmelik çerçevesinde çalışmalarına rağmen şikâyetlerin alınma ve değerlendirme sürecinde uygulama farklılıkları olabilmektedir. Bu farklılıklardan biri de Müdürlüğümüzün iş akışını hızlandırmak amacıyla geliştirdiği bir yazılımla şikâyetleri alıp değerlendirmesidir. Tüketici Sorunları Hakem Heyetlerinin raporlarına ait ülke çapında sistemli bir veri tabanı olmalı; Hakem Heyetlerinin uygulamalarına ve karar sonuçlarına yönelik karşılaştırmaların yapılarak, tüketici sorunlarının detaylı tetkiki sonucu üretilecek çözümlerle tüketici mağduriyetlerinin önüne geçilmelidir. Ground Jury of the Consumer Issues Reports and Consumer Behavior: Odunpazarı Example This study is an example of application with Law No. 4077 on Consumer Protection offered to judicial system functioning ground jury of the consumer Issues, about the process complaints of inclusion and assessment aims to provide generated solutions to consumer problems and consumer behavior of Odunpazarı district with 358.566 population. Our study contains; with the regulation 25 on ground jury of the consumer
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Kıbrıs’ta Yetiştirilen Bazı Turunçgil Meyvelerinin Kabuk Yağları Üzerinde Araştırmalar
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Ayten Doğan
2015-02-01
Full Text Available Araştırmamızda, Kıbrıs’ta yetiştirilen Valensiya ve Yafa portakal çeşitleriyle, Kıbrıs limonu ve Marsh Seedless altıntop’unun kabuk uçucu yağları incelenmiştir. Yapılan analizler de saptanan fiziksel ve kimyasal özelliklerle gaz kromatografik sonuçlar Valensiya, Yafa portakalı, Kıbrıs limonu ve Marsh Seedless altıntopu sırasıyla şöyledir. Yoğunluk (d20o: 0.8413, 0.8411, 0.8478, 0.8565, kırılma indisi (nD20o: 1.4731, 1.4730, 1.4750, 1.4790, çevirme derecesi (µD20o: +99.2, +98.2, +76.1, +91.8, asit sayısı: 1.64, 1.86, 1.36, 1.68, alkolde çözünürlük (%90: 8.1, 7.7, 6.6, 8.3, sabunlaşma sayısı: 3.36, 7.48, 5.76, 13.28, ester sayısı: 1.72, 5.59, 4.40, 11.60, ester miktarı (%: 0.70, 2.64, 2.28, 4.24, serbest alkol miktarı (%: 1.53, 2.41, 4.18, 5.40, aldehit miktarı (%: 3.66, 5.44, 3.31, 2.54, buharlaşma artığı (%: 2.79, 0.04, 4.52, 10.32 olarak saptanmıştır. Gaz kromatografik analiz sonucunda 16 bileşen saf standartlar yardımıyla teşhis edilmiş olup, terpenlerin % de miktarı portakallarda %98.78-98.89, limonlarda %96.72-97.56, altıntoplarda ise %98.31-98.65 arasında bulunmuştur. Dolayısıyla görülmektedir ki oksijenli bileşiklerin miktarı portakallarda %1.11-1.22, limonlarda %2.44-3.28, altıntoplarda da %1.35-1.69 arasında değişmektedir. Turunçgillerin aromasında asıl önemli olan bileşikler bu çok az miktarda olan oksijenli bileşiklerdir. Aynı zamanda bu bileşikler uçucu yağın kalitesini de ortaya koymaktadır.
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The BLSTs Role in the Materiel Enterprise
2016-05-17
CECOM AVN LAR AMCOM LAR PM UAS CECOM AVN LAR AMCOM LAR PM UAS CECOM AVN LAR PM UAS Ba gr am Sh an k M ar m al Ja la la ba d Legend Coordinating...relationship Administrative control AED = Aviation Engineering Directorate AMCOM = Aviation and Missile Command AVN = Avionics BLST = Brigade logistics
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Genus 4 trigonal reduction of the Benney equations
International Nuclear Information System (INIS)
Baldwin, Sadie; Gibbons, John
2006-01-01
It was shown by Gibbons and Tsarev (1996 Phys. Lett. A 211 19, 1999 Phys. Lett. A 258 263) that N-parameter reductions of the Benney equations correspond to particular N-parameter families of conformal maps. In recent papers (Baldwin and Gibbons 2003 J. Phys. A: Math. Gen. 36 8393-417, Baldwin and Gibbons 2004 J. Phys. A: Math. Gen. 37 5341-54), the present authors have constructed examples of such reductions where the mappings take the upper half p-plane to a polygonal slit domain in the λ-plane. In those cases, the mapping function was expressed in terms of the derivatives of Kleinian σ functions of hyperelliptic curves, restricted to the one-dimensional stratum Θ 1 of the Θ-divisor. This was done using an extension of the method given in Enolskii et al (2003 J. Nonlinear Sci. 13 157) extended to a genus 3 curve (Enolski V Z and Gibbons J Addition theorems on the strata of the theta divisor of genus three hyperelliptic curves, in preparation). Here, we use similar ideas, but now applied to a trigonal curve of genus 4. Fundamental to this approach is a family of differential relations which σ satisfies on the divisor. Again, it is shown that the mapping function is expressible in terms of quotients of derivatives of σ on the divisor Θ 1 . One significant by-product is an expansion of the leading terms of the Taylor series of σ for the given family of (3, 5) curves; to the best of the authors' knowledge, this is new
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Special polynomials associated with some hierarchies
International Nuclear Information System (INIS)
Kudryashov, Nikolai A.
2008-01-01
Special polynomials associated with rational solutions of a hierarchy of equations of Painleve type are introduced. The hierarchy arises by similarity reduction from the Fordy-Gibbons hierarchy of partial differential equations. Some relations for these special polynomials are given. Differential-difference hierarchies for finding special polynomials are presented. These formulae allow us to obtain special polynomials associated with the hierarchy studied. It is shown that rational solutions of members of the Schwarz-Sawada-Kotera, the Schwarz-Kaup-Kupershmidt, the Fordy-Gibbons, the Sawada-Kotera and the Kaup-Kupershmidt hierarchies can be expressed through special polynomials of the hierarchy studied
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ÇEVİRME, Ayşe
2017-01-01
ÖZETMobbing(psikolojik taciz) veya yıldırma, iş sağlığı alanında sıkça dile getirilen bir konu olup, akademi ve iş çevrelerinin dikkatini gittikçe daha fazla çektiği görülmektedir. Mobbing önlenebilir bir halk sağlığı sorunudur. Birey ve işyeri bağlamında önemli olumsuz sonuçları olan mobbing ile ilgili çalışmalar 1990’larda başlamıştır. Mobbing kavramı bir veya daha fazla kişi tarafından bir kişiye uygulanan etik olmayan ve muhalif davranış varlığı olarak tanımlanır. Bu yazıda mobbingin tan...
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KÖSE, İbrahim; KOPARAL, Mahmut; ALAN, Hilal; KIRTAY, Mustafa; ÇİÇEK, Yasin
2015-01-01
Diş hekimliğinde özellikle oral cerrahi müdahaleler neticesinde ağrı, şişlik ve trismus gibi rahatsızlıklar meydana gelebilmektedir. Kuşkusuz, meydana gelen problemler ve inflamatuvar süreci farmakolojik olarak kontrol altına almak amacıyla birçok analjezik ilaç kullanılmaktadır. Bu çalışmanın amacı; oral cerrahi müdahaleler sonrası kullanılan ağrı kesici ilaçların, kullanımı ve etkinliği konusundaki mevcut bilgileri güncellemek ve daha önce yapılmış çalışmaların ışığı altında uygulama yönte...
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Directory of Open Access Journals (Sweden)
Carla Aparecida Cielo
2015-04-01
Full Text Available OBJETIVO:verificar a diferença entre o tempo máximo de fonação /a/ e tempo máximo de fonação previsto em relação ao tipo respiratório, e correlacionar os tempos máximos em mulheres adultas com capacidade vital dentro da normalidade e sem afecções laríngeas.MÉTODOS:pesquisa transversal analítica, quantitativa e retrospectiva, em banco de dados, de 51 sujeitos do sexo feminino, com diagnóstico otorrinolaringológico de ausência de afecção laríngea, com idades entre 18 e 44 anos (média 27,64. Utilizaram-se os dados: maior valor de tempo máximo de fonação de /a/, tempo máximo de fonação previsto, capacidade vital e tipo respiratório. O valor do tempo máximo previsto para mulheres foi calculado multiplicando-se a capacidade vital por 0,0051, e o valor encontrado foi determinante para a classificação do tempo de /a/ em normal, abaixo ou acima do previsto.RESULTADOS:houve diferença significante entre tempo de fonação previsto e os tipos respiratórios superior (17,44s e misto (15,17s. Não houve diferença significante do tempo máximo de fonação /a/ nos diferentes tipos respiratórios, nem correlação entre tempo de fonação /a/ e tempo previsto.CONCLUSÃO:não houve correlação entre tempo de /a/ e tempo de fonação previsto e este último foi significantemente maior no tipo respiratório superior do que no misto na população estudada.
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APAYDIN ŞEN, Hatice
2017-01-01
Bu araştırmada öğretmenlerin kullandıkları duygusal emek stratejilerini, öğretmenlerin güdülenme türlerinin yordayıp yordamadığı ile öğretmenlerin güdülenme türü ve kullandıkları duygusal emek stratejilerini, öğretmen özgecilik davranışları ve kişilik özelliklerinin hangi düzeyde yordadığı incelenmiştir. Ayrıca, öğretmenlerin güdülenme türleri ve kullandıkları duygusal emek stratejilerinin, öğretmenliği seçme nedenleri, mesleğe devam etme nedenleri, cinsiyet, deneyim yılı, ...
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Directory of Open Access Journals (Sweden)
Noemi Grigoletto De Biase
2006-08-01
Full Text Available Distonias são desordens orgânicas do processamento motor central caracterizadas por contrações musculares involuntárias e espasmos à fonação nas formas laríngeas adutoras, com quebras de sonoridade. O diagnóstico é clínico e baseado na avaliação perceptivo-auditiva da voz e nasofibroscopia. OBJETIVO: O nosso objetivo é propor e avaliar um protocolo de exame de nasofibrolaringoscopia que contemple tarefas que evidenciem os espasmos e tarefas que diminuam ou façam desaparecer os espasmos, visando facilitar a análise e o diagnóstico. MATERIAL E MÉTODO: Estudo transversal. Análise de imagens de 15 videonasolaringoscopias de pacientes com distonia laríngea de adução por meio do protocolo proposto. RESULTADOS: A maior parte das tarefas de fala e não-fonatórias permitiram a identificação de espasmos e a diminuição ou desaparecimento destes. Propomos a exclusão de duas delas que não acrescentaram dados à avaliação. CONCLUSÃO: O protocolo foi útil na avaliação dos pacientes, mostrando mudança de comportamento da musculatura nas estruturas estudadas conforme as tarefas executadas.Dystonias are organic central motor processing disorders characterized by involuntary muscular contractions or incontrollable spasms induced by task-specific movements. Adduction laryngeal dystonias present with important speech impairments, with inappropriate spasms and abrupt voice breaks. The diagnosis is based on clinical features, evaluation by a speech therapist and transnasal fiber optic laryngoscopy. AIM: Our objective is to propose and evaluate a task-oriented transnasal fiber optic laryngoscopy protocol, which shows the spasms, and propose maneuvers that reduce or make them disappear, in order to facilitate the diagnosis. METHODS: transversal study. Analysis of the transnasal fiber optic laryngoscopy records of 15 patients with adductor laryngeal dystonia using the proposed protocol. RESULTS: most of the speech and non-vocal tasks
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Directory of Open Access Journals (Sweden)
Nurhan ÖZTÜRK GEREN
2014-12-01
Full Text Available Bu çalışmanın amacı, 6.sınıf ışık ve ses ünitesinde 5E öğrenme modeline dayalı etkinliklerin öğrencilerin bilimsel süreç becerileri ve akademik başarıları üzerindeki etkisini belirlemek ve bu etkinliklerin derste kullanımına yönelik öğrenci görüşlerini tespit etmektir. Bu amaca hizmet etmesi açısından 5E öğrenme modeline dayalı olarak rehber etkinlik seti geliştirilmiş ve setin süreçte etkililiği değerlendirilmiştir. 2011-2012 eğitim-öğretim yılında Sinop ili merkez ilçesinde bir ilköğretim okulunda altıncı sınıfa devam eden 25 deney ve 17 kontrol grubu öğrencisi ile gerçekleştirilen bu araştırmada karma yöntemler araştırma yöntemi kullanılmıştır. Araştırmanın nicel bölümünde, ön test son test kontrol gruplu deneysel desen kullanılmıştır. Araştırmanın deney grubu öğrencileri ile gerçekleştirilen nitel bölümünde ise durum çalışması (casestudy yöntemi kullanılmıştır. Araştırma süresince elde edilen nicel verilerin analizleri SPSS 15.0 istatistik paket programı ile nitel verilerin analizi ise içerik analizi ve sürekli karşılaştırılmalı veri analizi yöntemleri birlikte kullanılarak NVivo 8.0 Nitel Veri Analizi Programı ile gerçekleştirilmiştir. Araştırmada 5E öğrenme modeline uygun hazırlanan rehber etkinlikleri ile desteklenen dersin öğrencilerin bilimsel süreç becerileri ve akademik başarıları üzerinde anlamlı ve olumlu etkisi olmuştur.
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Directory of Open Access Journals (Sweden)
Furkan SARSILMAZ
2009-04-01
Full Text Available Bu çalışmada farklı kimyasal ve mekanik özelliklere sahip AA 5754 (AlMg3 ile AA 5083 (AlMg4,5Mn0,7 alüminyum alaşım levhaları, günümüzde yeni geliştirilen sürtünme karıştırma kaynak (SKK yöntemiyle birleştirilmiştir. Çalışmada farklı devir ve ilerleme hızlarının, kaynaklı bağlantıların mekanik özelliklerini belirlemek amacıyla tahribatlı (çekme, çentik darbe, ve yorulma ve tahribatsız (floroskopik testler uygulanmıştır. Tahribatlı testler sonucunda farklı kaynak dönme ve ilerleme hızlarının, bağlantının mekanik test sonuçlarını etkilediği belirlenmiştir. Tahribatsız test sonucunda ise düşük devir sayısının ve yüksek ilerleme hızının, kaynak bölgesinde yetersiz birleşme meydana getirmesiyle, dikiş boyunca bölgesel porozite, tünel ve boşluklu bölgelerin oluştuğu görülmüştür. En iyi mekanik test sonucunu, 1400 devir dönme hızı ve 250 mm/dak ilerleme hızı işlem parametresi ile birleştirilen numune sergilemiştir. Anahtar Kelimeler: Sürtünme Karıştırma Kaynağı, Alüminyum Alaşımları, Tahribatlı Ve Tahribatsız Muayene, Kaynak Bölgesi
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Directory of Open Access Journals (Sweden)
MERVE ÇAKIR
2012-12-01
Full Text Available Günümüzde tüketiciler sadece ihtiyaçlarına yönelik alışveriş yapmayıp, duygusal anlamda haz duyabileceği ya da alışveriş esnasında zevk alabileceği alışverişler yapmaktadırlar. Modern tüketim toplumlarında tüketim olgusunun duygusal veya hissi boyutu ön plana çıkmış, satın alma sürecinde geleneksel anlayıştan belirgin derecede farklılıklar gösteren hedonik (hazcı tüketim tüketici davranışları açısından giderek daha fazla oranda inceleme konusu olmaya başlamıştır. Pazarlama iletişiminde de firmaların hedef kitleleri genç tüketiciler olarak belirmektedir. Bu çalışma, genç tüketicilerin alışverişe bakışlarında gittikçe önemli bir yer alan hedonik tüketimin nedenlerini incelemeyi amaçlamaktadır. Analysis of Hedonic Consumption Behaviours of the Young People Aged 12-18: A Research in the City Center of Kocaeli At the present time, the consumers have not only been shopping just for their needs, but also for pleasure or to get a kick out of shopping. In modern consumption societies, the emotional dimension of consumption have come into prominence and the hedonic consumption at the process of purchasing that have significant differences from traditional mentality have increasingly been subject to researches. Also in marketing communication, the target audiences of the companies have appeared as young consumers. This study aims researching the reasons of the hedonic consumption which increasingly encompass an important place at the outlooking of the young consumers to shopping.
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Kawada, Kenji; Sakai, Yoshiharu
2016-07-07
Anastomotic leakage (AL) is one of the most devastating complications after rectal cancer surgery. The double stapling technique has greatly facilitated intestinal reconstruction especially for anastomosis after low anterior resection (LAR). Risk factor analyses for AL after open LAR have been widely reported. However, a few studies have analyzed the risk factors for AL after laparoscopic LAR. Laparoscopic rectal surgery provides an excellent operative field in a narrow pelvic space, and enables total mesorectal excision surgery and preservation of the autonomic nervous system with greater precision. However, rectal transection using a laparoscopic linear stapler is relatively difficult compared with open surgery because of the width and limited performance of the linear stapler. Moreover, laparoscopic LAR exhibits a different postoperative course compared with open LAR, which suggests that the risk factors for AL after laparoscopic LAR may also differ from those after open LAR. In this review, we will discuss the risk factors for AL after laparoscopic LAR.
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Directory of Open Access Journals (Sweden)
Adem BALKAYA
2012-12-01
lkelden moderne kadar her insanın bu sorulara cevap bulmak veya etrafında olup biteni anlamaya/açıklamaya yönelik gayretleri farklı anlatım ve inanmaları doğurmuştur. Varlığın ne, neden ve nasıl olduğuna dair felsefi tartışmalar bir yana bırakılırsa sosyologlar din denen olguyu, arkaik insanın bu problematiğe bulduğu sağlam bir dayanak olarak açıklarlar. Bunun yanında neredeyse din hüviyetine dönen kimi yaratım anlatmaları da doğmuştur ki halkbilimin uğraşı alanına girerler. Kozmogoniler işte bu ilk olanın nasıl olduğunu izaha kalkan insanın tecrübeleridir. Bu anlatılar dikkatle irdelendiğinde kimi ortaklıklara tesadüf edilmektedir. Ortaklıklardan biri de anlatıların dikotomik bir temellendirme ile sunulmuş olmalarıdır. Zira anlatımı zıt veya zıt görünen iki şey üzerinden kurmak anlatıya kimi ilginç özellikler kazandırmaktadır. Hatta dikkatle incelendiğinde bu türden temellendirmenin bir ihtiyaç dahilinde yapıldığı da anlaşılmaktadır. Bir varlığı izah etmede, ona belirli bir sınırlama getirmede veya onu başka açılardan tamamlamada bir diğer şeye müracaat edilir. Kozmogonilerin de dünyayı, doğayı veya varlığı açıklama ve mantıklı sebepler bulma olan asıl misyonları da bu yolla gerçeklemiş olur. Bu çalışmada kozmogoni anlatılarında bu temellendirmelerden örnek teşkil etmesi amacıyla –bütün kozmogonilerin işlenmesi çalışmanın kapsamını aşacağından- bir kaçı üzerinde durulacak ve anlatılarda neden bir dikotomik temellendirilmeğe gidildiği tartışılacaktır.
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Directory of Open Access Journals (Sweden)
Betül Öztürk
2015-02-01
Full Text Available Bu çalışmada, Türkiye’nin zeytinyağı üretiminin % 65’ini Oluşturan Ege bölgesinin hakim zeytin çeşidi olan Ayvalık ve Memecik yağ örneklerinin en yaygın spektroskopik yöntemler ile (FTNIR, FTIR-ATR, Excitation-Emission [EX-EM] ve Senkronize [SYN] Floresans Spektroskopisi analiz edilerek sınıflandırılması gerçekleştirilmiştir. Analiz edilen yağ örnekleri organik ve karışık çeşitlerden üretilen bir örnek dışında Kuzey Ege (Ayvalık çeşidi (n=4 ve Güney Ege (Memecik çeşidi (n=4 alt bölgelerinden alınmış toplam 9 adetten Oluşmaktadır. Oda sıcaklığında PET şişeler içinde muhafaza edilen yağ örnekleri gün ışığına maruz bırakılan ve aluminyum folyo ile kaplanmış (karanlık olarak iki gruba ayrılmıştır. Ayvalık ve Memecik çeşidi natürel zeytinyağlarının sınıflandırılması en yaygın kullanılan kemometrik yöntemler ile (Temel Bileşen Analizi, PCA ve Aşamalı Kümeleme Analizi, HCA gerçekleştirilmiştir. Ayvalık ve Memecik çeşitleri spektroskopik yöntemlerin sonuçları temelinde çeşit, orijin bölgesi ve işlem uygulamalarına (ışığa maruz kalma veya karanlıkta tutma gibi göre dikkate değer bir şekilde sınıflanmışlardır. Ayrıca, spektroskopik yöntemlerin natürel zeytinyağların sınıflandırılmasında ve muhtemel depolama koşulları ve tağşiş konusunda ümitvar etkiler sergileyebileceği görülmüştür.
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Obituary: Gary Lars Grasdalen, 1945-2003
Strom, Stephen Eric
2003-12-01
With the passing of Gary Grasdalen on 20 April 2003 the astronomical community has lost one its most creative members. Born in Albert Lea, Minnesota on 7 October 1945 to the farming family of Lars G. and Lillie Grasdalen, Gary developed a strong childhood interest in science, and a particular fascination with astronomy. In 1964, he entered Harvard College intending to pursue those interests. During his freshman year, Gary enrolled in an undergraduate research seminar in which he first displayed the combination of keen insight and imagination in applying new techniques that was manifest throughout his professional career. In 1968, he published his first two papers---studies of the C12/C13 ratio in metal deficient stars, and of Fe I and Fe II transition probabilities---which summarized research carried out during his junior and senior years at Harvard. Grasdalen next entered the astronomy graduate program at the University of California, Berkeley. There he developed a strong interest in the early stages of stellar evolution and, in particular, the potential of S-1 image intensifiers and newly available near-infrared detectors to detect and analyze the stellar populations embedded within their parent molecular cloud complexes. Following award of his PhD in 1972, Grasdalen was appointed to the staff at the Kitt Peak National Observatory. Early in his career at KPNO, Gary developed tools that enabled routine near-infrared mapping of nearby molecular cloud complexes, most notably the telescope control programs that enabled precise raster scanning of these regions. Those same programs were some of the many innovations in which Gary had a hand. These innovations enabled a generation of KPNO observers in the 1970s to fully exploit the power of the newly commissioned Mayall telescope as well as the smaller telescopes on Kitt Peak. In 1973, he published the first map of the central region of a molecular cloud, which revealed an extensive embedded, optically obscured
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Functional results after treatment for rectal cancer
Directory of Open Access Journals (Sweden)
Katrine Jossing Emmertsen
2014-01-01
Full Text Available Introduction: With improving survival of rectal cancer, functional outcome has become in- creasingly important. Following sphincter-preserving resection many patients suffer from severe bowel dysfunction with an impact on quality of life (QoL – referred to as low ante- rior resection syndrome (LARS. Study objective: To provide an overview of the current knowledge of LARS regarding symp- tomatology, occurrence, risk factors, pathophysiology, evaluation instruments and treat- ment options. Results: LARS is characterized by urgency, frequent bowel movements, emptying difficulties and incontinence, and occurs in up to 50-75% of patients on a long-term basis. Known risk factors are low anastomosis, use of radiotherapy, direct nerve injury and straight anasto- mosis. The pathophysiology seems to be multifactorial, with elements of anatomical, sen- sory and motility dysfunction. Use of validated instruments for evaluation of LARS is es- sential. Currently, there is a lack of evidence for treatment of LARS. Yet, transanal irrigation and sacral nerve stimulation are promising. Conclusion: LARS is a common problem following sphincter-preserving resection. All pa- tients should be informed about the risk of LARS before surgery, and routinely be screened for LARS postoperatively. Patients with severe LARS should be offered treatment in order to improve QoL. Future focus should be on the possibilities of non-resectional treatment in order to prevent LARS. Resumo: Introdução: Com o aumento da sobrevida após câncer retal, o resultado funcional se tornou cada vez mais importante. Após ressecção com preservação do esfíncter, muitos pacientes sofrem de disfunção intestinal com um impacto sobre a qualidade de vida (QdV – denomi- nada síndrome da ressecção anterior baixa (LARS. Objetivo do estudo: Fornecer uma visão geral do conhecimento atual da LARS com relação à sintomatologia, à ocorrência, aos fatores de risco, à fisiopatologia, aos
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Zhang, Zhong; Li, Qiang; Liu, Fengchen; Sun, Yuqian; Zhang, Jinchao
2010-03-15
The aim of this study was to investigate the prevention of diet-induced obesity by a high safflower oil diet and adipocytic gene expression in mice. Forty 3-week-old C57BL/6 mice were randomly divided into three groups: control group (CON, 5% lard + 5% safflower oil), high lard group (LAR, 45% lard + 5% safflower oil), and high safflower oil group (SAF, 45% safflower oil + 5% lard). After 10 weeks, 10 mice of the LAR group were switched to high safflower oil diet (LAR-SAF). Ten weeks later, glucose tolerance tests were performed by intraperitoneal injection of glucose. Circulating levels of lipid and insulin were measured and white adipose tissues were taken for gene chip and reverse transcriptase-polymerase chain reaction analysis. The LAR group showed higher body weight, adiposity index, insulin, and lipids than the CON group (P<0.05). The body weight in the LAR-SAF group decreased after dietary reversal. The plasma biochemical profiles decreased in the LAR-SAF and SAF groups (P<0.05) compared with those of the LAR group. The blood glucose level of the LAR-SAF group was reduced during intraperitoneal glucose tolerance test compared with that of the LAR group. The LAR-SAF group had lower levels of Orexin and Ghrelin gene expression, whereas the level of PPARalpha gene expression was significantly enhanced compared with that of the LAR group. So, the SAF diet can alter adipocytic adiposity-related gene expression and result in effective amelioration of diet-induced obesity.
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Directory of Open Access Journals (Sweden)
Ali Çağlar Çakmak
2017-10-01
Full Text Available Abstract The service which is provided by courier companies that we often use in our daily life has a great importance for their customers. To deliver a received or sent cargo on time without having damage is one of the most effective factors that comprise this importance. From this point of view, the main purpose of this study is to determine the services that the customers set great care about and to find out to what extent can the courier companies fulfill these demands. For this purpose, in this study the evaluation of the companies by the customers are assessed by using importance-performance analysis. According to the obtained results, the factors which the customers set care the most are; “delivering the post without any deficiency”, “not to open” and “delivering to designated address”. The least important factors are; “to ask help while carrying the cargo”, “the physical conditions of the company” and “applying existing campaigns”. When we look at the courier companies, through the most preferred three companies: Yurtiçi Cargo, Aras Cargo and PTT Cargo, “PTT Cargo” has the highest performance average while “Yurtiçi Cargo” has the lowest. Öz Günlük hayatımızda sıklıkla kullandığımız kargo firmalarının verdikleri hizmet, bu hizmeti alan kullanıcıları için büyük önem arz etmektedir. Gönderilen veya alınan kargonun zamanında teslim edilmesi, herhangi bir hasar görmemesi de bu önemin oluşmasındaki en etkili unsurlardandır. Buradan hareketle bu çalışmanın ana amacı, kullanıcıların en çok önem verdikleri hizmetlerin belirlenmesi ve çalıştıkları kargo firmalarının bu hizmetleri ne ölçüde yerine getirebildiklerinin ortaya çıkarılmasıdır. Bu amaçla, bu çalışmada kullanıcıların kargo firmalarını değerlendirmeleri önem-başarım analizi kullanılarak ölçülmüştür. Elde edilen sonuçlara göre kullanıcıların en çok önem verdiği unsurlar; g
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Directory of Open Access Journals (Sweden)
Büşra Halis
2012-12-01
Full Text Available İnsanlık tarihi kadar eski olan tüketim, zaman içerisinde yaşanan değişim ve dönüşümlerle birlikte yeni bir boyut kazanmıştır. Eskinin, ihtiyacı kadar almak ve çalışmak gibi fenemonlerinin yerini, günümüzde daha çok satın almak için çalışmak, tükettiğinin ölçüsünde var olabilmek ya da olamamak almıştır. Tüketimin soyut anlamda kavramsal içeriğinin farklılaşmasının yanı sıra, tüketim araçları da farklılaşmıştır. Artık, yüz yüze görüşmeler yoluyla yapılan alışverişlerin yerini; fiziki mekândan bağımsız, internet üzerinden e-ticaret yoluyla ve birtakım paylaşım ağları aracılığıyla yapılan alışverişler almıştır. Bu çalışmada da, tüketimin ve tüketimde kullanılan araçların geçmişten bugüne değişen anlamı ve bu değişimi körükleyen sosyal ağ paradigması tartışılmaktadır. The Changing Face of Consumption: E-Commerce Applications And The Role of Social Networks Consumption, which is as old as human history has gained a new dimension with changes and transformations in the course of time. In the past, people bought and worked as they needed, but now, they work to buy more things except necessity and they be or not to be until they consumed. Over time, the conceptual content and tools of the consumption has changed. Shopping, which is done independent of the physical space, via the internet through e-commerce replaced shopping made by face to face. In this work, the changing meaning and tools of consumption from past to present and the paradigm of social networks which encouraging this change is to be held.
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Özgür Külcü
2014-12-01
Full Text Available Dünyada ve Türkiye’de sosyal paylaşım siteleri arasında en yaygın kullanım oranına sahip Facebook üzerindeki risk ve tehditlerden uzak kalabilmenin tek yolu; bilinçli kullanım ile varsayılan ayarlar üzerinde değişiklik yapmak ya da Facebook hesabına sahip olmamaktır. Türkiye’de sosyal paylaşım sitelerinde açığa çıkan kişisel bilgilerin gizlilik açısından değerlendirildiği bir çalışma literatürde yer almamaktadır. Bu nedenle, çalışma sonunda elde edilen bulgular, kullanıcıları yeterince koruyan hukuksal düzenlemelerin bulunmadığı Türkiye’de, mevcut durumun ortaya konularak bu konudaki risklere dikkat çekilmesi açısından da önem taşımaktadır. Bu çalışmada, KUTUP-L üyesi bilgi profesyonellerinin Facebook gizliliği incelenerek; Türkiye’de bilgi profesyonellerinin gizlilik konusundaki hassasiyeti ve bilinçlenme düzeyinin belirlenmesi amaçlanmaktadır. Çalışmada, 400 KUTUP-L üyesi bilgi profesyonelinin Facebook kullanıcı profili, 32 farklı gizlilik ayarı dikkate alınarak incelenmiştir. Her kullanıcı için bir gizlilik puanı hesaplanmış ve ayrıca tüm gizlilik sonuçları arasındaki ilişkiler incelenmiştir. Çalışma sonunda elde edilen bulgular; Türkiye’deki bilgi profesyonellerinin gizliliğe önem verdiklerini ve büyük çoğunluğun kişisel verilerini korumak amacıyla varsayılan ayarlar üzerinde değişiklik yaptıklarını göstermektedir./The only way to beware of the risks and threads of Facebook, the most commonly used social networking site in the world and Turkey, is to be a conscious user changing the default settings or simply not to have a Facebook account. In Turkey, there is still not any study in which personal information shared though social networking sites has been evaluated in terms of privacy in the literature. For this reason, the findings obtained as a result of this study have a great importance in the sense of displaying the
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Directory of Open Access Journals (Sweden)
Alper BAŞBAY
2013-03-01
ıduyulmasını sağlayacak biçimde ortak anlaşma çerçevesinde inşaedilmesi temel beklentidir. Özellikle ilköğretim ve ortaöğretimkurumlarında çalışan öğretmenlerin farklı kültürel özelliklere sahipöğrencilerine yönelik etkin bir çokkültürlü eğitim ortamı oluşturmasıgerektiği kaçınılmaz bir olgudur. Bu bağlamda öğretmen adaylarınıyetiştiren Eğitim Fakültelerinde görev yapmakta olan öğretimelemanlarının çokkültürlülüğe ilişkin bakış açılarının ortaya konulmasıgerekmektedir. Bu araştırmada Türkiye’deki üniversitelerin EğitimFakültelerinde görev yapmakta olan öğretim elemanlarının algıladıklarıçokkültürlü farkındalık, bilgi ve beceri düzeyleri ve bu yeterlikdüzeylerinin cinsiyet, unvan, iş deneyimi, yurtdışı deneyimi, yaşantınınçoğunun geçirildiği yer ve üniversitelerinin bulunduğu coğrafi bölgedeğişkenlerine göre anlamlı farklılıklar gösterip göstermediğiincelenmiştir. Çalışmaya 63 Eğitim Fakültesinden 176’sı kadın ve 171’ierkek olmak üzere toplam 347 öğretim elemanı katılmıştır.Araştırmanın verileri “Çokkültürlü Yeterlik Algıları Ölçeği” iletoplanmıştır. Verilerin analizinde çok değişkenli ANOVA (MANOVAkullanılmıştır. Araştırmanın sonuçlarına göre Eğitim Fakültelerindegörev yapmakta olan öğretim elemanlarının çokkültürlü bilgi,farkındalık ve beceri yeterlik algılarının yüksek olduğu görülmüştür.Araştırmanın diğer bulgularına göre öğretim elemanlarının çokkültürlüyeterlik algılarında unvan, iş deneyimi, yaşantının çoğunun geçirildiğiyer ve üniversitelerinin bulunduğu coğrafi bölge değişkenlerine göreanlamlı farklılıklar bulunamamışken, cinsiyet ve yurtdışı deneyimolmak üzere iki demografik değişken yönünden istatistiksel olarakanlamlı farklılıklar görülmüştür. Kadın öğretim elemanlarının kültürelfarkındalık ve beceri düzeylerinin erkek
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Okul Öncesi Öğretmenlerinin Riskli Oyunlara Yönelik Görüş ve Algıları
Directory of Open Access Journals (Sweden)
B. İpek Güler
2016-08-01
Full Text Available Çocukların oyunlarında heyecan aramak için yaptıkları ve fiziksel olarak yaralanma riski olan oyunlar riskli oyun kavramı altında tartışılmaktadır. Bu çalışmada, okul öncesi eğitim kurumlarında görev yapan öğretmenlerin çocukların riskli oyunlarına yönelik görüş ve algılarının incelenmesi amaçlanmıştır. Bu araştırma nitel araştırma yaklaşımıyla açımlayıcı bir araştırma olarak yürütülmüştür. 2015-2016 eğitim ve öğretim yılında Ankara ilindeki altı farklı okul öncesi eğitim kurumunda görev yapan toplam 25 öğretmen çalışma grubunu oluşturmuştur. Veriler araştırmacılar tarafından geliştirilen bir görüşme formu kullanılarak ve birebir görüşmeler yoluyla toplanmıştır. Görüşmelerin dökümü ile elde edilen dokümanlar üzerinde belge tarama yapılmış ve öğretmen görüşlerinin sıklık dağılımları üzerinden analizler gerçekleştirilmiştir. Araştırma sonucunda, çalışma grubunda bulunan öğretmenlerin riskli oyunlara karşı temkinli yaklaştıkları belirlenmiştir. Çocukların fiziksel sağlıklarına verilen önem onların risk almalarının önünde bir engel olarak görülmektedir. Bunun, risk kavramının tehlikeli ve zarar verici olarak algılanmasından kaynaklanabileceği gözlemlenmiştir. Diğer taraftan velilerin ve idarecilerin öğretmenler ve oyunlara yönelik tutumlarının, ayrıca fiziksel altyapı sorunlarının da riskli oyunları engelleyen diğer etkenler arasında olabileceği görülmüştür. The concept of risky play is discussed under the name of play, which seeks excitement and involves a risk of physical injury. In this study, it was aimed to examine the pre-school teachers’ opinions and perceptions toward risky play. This study was conducted as a basic and exploratory research according to the qualitative approach Totally 25 pre-school teachers working at six different schools at 2015-2016 term dates in Ankara
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Directory of Open Access Journals (Sweden)
Barış Kuleyin
2014-12-01
Full Text Available Deniz Ulaştırma İşletme Mühendisliği bölümünde verilen “Seyir” dersi, uzakyol vardiya zabitliği eğitimi için en temel ve önemli derslerden birisidir. Çalışmanın amacı, seyir dersine ilk kez giren öğrencilerin dersle ilgili dönem başı ve dönem sonundaki olası algı farklılıklarını ortaya koymaktır. Bu amaca yönelik olarak, Dokuz Eylül Üniversitesi (DEÜ Denizcilik Fakültesi’nde öğrenim gören ve seyir dersine ilk kez giren 61 öğrenciye, dönem başında ve dönem sonunda olmak üzere iki defa Geiger ve Ogilby (2000 tarafından geliştirilmiş olan bir anket formu uygulanmıştır. Söz konusu anket, şu sorulara cevap aramaktadır: 1 Öğrencilerin seyir dersine yönelik dönem başı algıları öğrencilerin memleketleri ve başarı düzeylerine göre farklılık gösteriyor mu? 2 Öğrencilerin seyir dersine yönelik dönem sonu algıları öğrencilerin memleketleri ve başarı düzeylerine göre farklılık gösteriyor mu? 3 Seyir dersine yönelik olarak öğrencilerin algısında eğitim periyodu sonunda bir değişiklik meydana gelmiş midir? Anket verilerinin analizinde SPSS 20 paket programı ve bağımsız t-testi yöntemi kullanılmıştır.
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"Lar, doce Lar": a perspetiva de morrer em casa...
Costa, Tânia; Souza, Cláudia; Coelho, Patrícia
2012-01-01
O avanço tecnológico contribuiu para generalizar a hospitalização do doente terminal. Contudo, contrariamente ao ambiente hospitalar, o domicílio detém componentes que proporcionam segurança, conforto e esperança no doente. Identificar as necessidades dos doentes/família em cuidados paliativos domiciliários para colmatar as lacunas entre cuidados atuais e desejos dos doentes. Priorizar e orientar a intervenção em cuidados paliativos.
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Directory of Open Access Journals (Sweden)
Hakan KURT
2013-09-01
listed as follows: “structure and properties of bacteria”, “bacteria identification”, “bacterial genetics”, “classification of bacteria” and “the formation of the nutrients and energy in bacteria”.Moreover, the data collected through two data collection instruments indicated that student teachers had misconceptions about bacteria considering the themes determined. Since this concept concerns many disciplines, it causes students to have difficulty in forming conceptual structures related to the concept of bacteria. Teachers play an important role in students' learning concepts. Teachers of biology, which is related to many disciplines, adopt great responsibility for students' forming and learning the appropriate conceptual structures related to the concept of bacteria. The reasons why students are successful or unsuccessful in learning concepts are the leading issue in educational research for an effective learning. In brief, attaching importance to concept teaching and learning at any stage of education and organizing learning-teaching activities accordingly are of high importance to meaningful learning. Therefore, it is necessary to determine students' conceptual structures, inaccurate and incomplete information, and concepts before starting to teach. Teaching and learning should be planned through suitable strategies, methods, and techniques. Thus, students can code meaningfully new concepts and information in their minds, and create accurate correlation between these concepts and information, which leads to more meaningful and permanent learning. Öğrencilerin bilgiyi zihinlerine nasıl aldıkları ve zihinlerinde nasıl yapılandırdıklarını anlamak araştırmacıların ilgisini çeken en önemli konulardan biridir. Yapılandırmacı öğrenme yaklaşımı bilginin birey tarafından zihinde aktif bir şekilde ön bilgileriyle ve önceki deneyimleriyle ilişkilendirilerek yapılandırıldığını ifade etmektedir (Anderson 1992; Bodner 1986
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Chen, Yue-yu; Liu, Zhao-hui; Zhu, Kun; Shi, Pei-dong; Yin, Lu
2013-06-01
It remains unknown whether transanal endoscopic microsurgery (TEMS) is superior to laparoscopic lower anterior resection (LAR) for the treatment of rectal cancer. This study aimed to compare the surgical and oncological effectiveness as well as safety of TEMS and LAR in T1-2 rectal cancer patients. T1-2N0 rectal cancer patients were prospectively and randomly assigned to local excision using TEMS (n=30) or radical resection using LAR (n=30). The primary outcome measures were postoperative recovery course. The operative duration of TEMS was significantly shorter than that of LAR (130.3±16.7 minutes vs. 198.7±16.8 minutes, pTEMS group restarted bowel movement significantly earlier than the LAR group (51.4±5.4h vs. 86.2±8.7h, pTEMS, respectively; no patient (0/30, 0.0%) developed local recurrence following LAR. TEMS was associated with more rapid postoperative recovery and minimal surgical morbidity in T1-2 rectal cancer patients as compared to LAR.
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ARIK, Selçuk; YILMAZ, Mehmet
2017-01-01
Bu çalışmanın amacı, fen bilimleri öğretmen adaylarının çevre sorunlarına yöneliktutumlarını ve çevre kirliliğine yönelik metaforik algılarını araştırmaktır. Araştırma 2013-2014eğitim öğretim yarıyılı güz döneminde Tokat Gaziosmanpaşa Üniversitesinde gerçekleştirilmiştir.Araştırmanın, çalışma grubunu fen bilimleri öğretmen adayları (n=132) oluşturmuştur.Araştırmada verileri toplamak amacıyla “Çevre Tutumları Ölçeği”(Yoldaş, 2009) ve metafortoplama formu kullanılmıştır. Bu araştırma da nicel a...
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Solvent sorting in (mixed solvent electrolyte) systems: Time-resolved ...
Indian Academy of Sciences (India)
lar solvents as an effective single component dipo- lar liquid that is characterized ... and time (t) dependent solvation energy of mobile dipo- lar solute with density ..... Even though this way for modification of C is purely ad- hoc, the observation ...
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Tunneling in cosmology and isothermal inflation
International Nuclear Information System (INIS)
Brout, R.; Spindel, P.
1991-01-01
The wave function for the universe, as proposed by Hartle and Hawking, experiences tunneling for small values of the radius of the universe. This induces thermal effects and so a hot big bang. We first give a detailed analysis of the observer accelerating in Minkowski space in terms of the tunneling of his wave function beyond his turning point. Applied to cosmology one finds a temperature at the big bang equal to the Gibbons-Hawking value. The residual thermal effects which result in an isothermal inflationary expansion give rise to a renormalized self-consistently determined Hubble constant (and hence Gibbons-Hawking temperature) through the trace anomaly. A thermodynamic interpretation is given. These results militate against phase transitions as a motor for inflation. (orig.)
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Dutch validation of the low anterior resection syndrome score.
Hupkens, B J P; Breukink, S O; Olde Reuver Of Briel, C; Tanis, P J; de Noo, M E; van Duijvendijk, P; van Westreenen, H L; Dekker, J W T; Chen, T Y T; Juul, T
2018-04-21
The aim of this study was to validate the Dutch translation of the low anterior resection syndrome (LARS) score in a population of Dutch rectal cancer patients. Patients who underwent surgery for rectal cancer received the LARS score questionnaire, a single quality of life (QoL) category question and the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire. A subgroup of patients received the LARS score twice to assess the test-retest reliability. A total of 165 patients were included in the analysis, identified in six Dutch centres. The response rate was 62.0%. The percentage of patients who reported 'major LARS' was 59.4%. There was a high proportion of patients with a perfect or moderate fit between the QoL category question and the LARS score, showing a good convergent validity. The LARS score was able to discriminate between patients with or without neoadjuvant radiotherapy (P = 0.003), between total and partial mesorectal excision (P = 0.008) and between age groups (P = 0.039). There was a statistically significant association between a higher LARS score and an impaired function on the global QoL subscale and the physical, role, emotional and social functioning subscales of the EORTC QLQ-C30 questionnaire. The test-retest reliability of the LARS score was good, with an interclass correlation coefficient of 0.79. The good psychometric properties of the Dutch version of the LARS score are comparable overall to the earlier validations in other countries. Therefore, the Dutch translation can be considered to be a valid tool for assessing LARS in Dutch rectal cancer patients. Colorectal Disease © 2018 The Association of Coloproctology of Great Britain and Ireland.
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Late Acute Rejection Occuring in Liver Allograft Recipients
Directory of Open Access Journals (Sweden)
Eric M Yoshida
1996-01-01
Full Text Available To study the effect of immunosuppressive reduction on the incidence and consequence of late acute rejection (LAR in liver allograft recipients, mean daily prednisone dose, mean cyclosporine A (CsA trough and nadir levels were retrospectively reviewed for the nearest 12-week period preceding six episodes of LAR in five liver allograft recipients (group 1. Results were compared with those from a cohort of 12 liver allograft recipients who did not develop LAR (group 2. LAR was defined as acute rejection occurring more than 365 days post-transplantation. Median follow-up for both groups was similar (504 days, range 367 to 1050, versus 511 days, range 365 to 666, not significant. Mean trough CsA levels were lower in patients with LAR compared with those without (224±66 ng/mL versus 233±49 ng/mL but the difference was not statistically significant. In contrast, mean daily prednisone dose (2.5±1.6 mg/ day versus 6.5±2.9 mg/day, P=0.007 and CsA nadir values (129±60 ng/mL versus 186±40 ng/mL, P=0.03 were significantly lower in patients who developed LAR compared with those who did not. Five of six episodes (83% of LAR occurred in patients receiving less than 5 mg/day of prednisone, versus a single LAR episode in only one of 12 patients (8% receiving prednisone 5 mg/day or more (P=0.004. In all but one instance, LAR responded to pulse methylprednisolone without discernible affect on long term graft function. The authors conclude that liver allograft recipients remain vulnerable to acute rejection beyond the first post-transplant year; and reduction of immunosuppressive therapy, particularly prednisone, below a critical, albeit low dose, threshold increases the risk of LAR.
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Directory of Open Access Journals (Sweden)
Yuepeng eHan
2015-04-01
Full Text Available Proanthocyanidins (PAs are the major component of phenolics in apple, but mechanisms involved in PA biosynthesis remain unclear. Here, the relationship between the PA biosynthesis and the expression of genes encoding leucoanthocyanidin reductase (LAR and anthocyanidin reductase (ANR was investigated in fruit skin of one apple cultivar and three crabapples. Transcript levels of LAR1 and ANR2 genes were significantly correlated with the contents of catechin and epicatechin, respectively, which suggests their active roles in PA synthesis. Surprisingly, transcript levels for both LAR1 and LAR2 genes were almost undetectable in two crabapples that accumulated both flavan-3-ols and PAs. This contradicts the previous finding that LAR1 gene is a strong candidate regulating the accumulation of metabolites such as epicatechin and PAs in apple. Ectopic expression of apple MdLAR1 gene in tobacco suppresses expression of the late genes in anthocyanin biosynthetic pathway, resulting in loss of anthocyanin in flowers. Interestingly, a decrease in PA biosynthesis was also observed in flowers of transgenic tobacco plants overexpressing the MdLAR1 gene, which could be attributed to decreased expression of both the NtANR1 and NtANR2 genes. Our study not only confirms the in vivo function of apple LAR1 gene, but it is also helpful for understanding the mechanism of PA biosynthesis.
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Farklılıkların Yönetimi ile Öğrenen Okul Arasındaki İlişkinin Öğretmen Algılarına Göre İncelenmesi
DOĞAN, Soner; UĞURLU, Celal Teyyar; TOPÇU, İhsan; YİĞİT, Yakup
2018-01-01
Araştırmanın amacı, öğretmenlerin farklılıkların yönetimi ile öğrenen okul algılarını belirlemek ve farklılıkların yönetimi ile öğrenen okul arasındaki ilişkinin düzeyini saptamaktır. Bu çerçevede araştırma, ilişkisel tarama modelinde desenlenmiştir. Araştırmanın çalışma grubunu Sivas iline Bağlı Zara ilçesinde ilk, ortaokul ve lise düzeyinde toplam 18 okulda görev yapan 161 öğretmen oluşturmaktadır. Araştırma verileri öğrenen okul ölçeği (ÖOÖ) ve farklılıkların yönetimi ölçeği (FYÖ) aracılığ...
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International Nuclear Information System (INIS)
Moon, A.M.; Ley, T.J.
1990-01-01
DNA sequences located in a region 6-18 kilobases (kb) upstream from the human ε-globin gene are known as the locus-activating region (LAR) or dominant control region. This region is thought to play a key role in chromatin organization of the β-like globin gene cluster during erythroid development. Since the human β-globin LAR is functional in mice, the authors reasoned that critical LAR sequence elements might be conserved between mice and humans. They therefore cloned murine genomic sequences homologous to one portion of the human LAR. They found that this murine DNA fragment (mouse LAR site II) and sequences homologous to human LAR sites I and III are located upstream from the mouse β-like globin gene cluster and determined that their locations relative to the cluster are similar to that of their human counterparts. The homologous site II sequences are 70% identical between mice and humans over a stretch of ∼800 base pairs. These results suggest that primary structural elements endash and the spatial organization of these elements endash are important for function of the β-globin LAR
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Directory of Open Access Journals (Sweden)
Zhijun Zhong
Full Text Available Giardia duodenalis is a common human and animal pathogen. It has been increasingly reported in wild and captive non-human primates (NHPs in recent years. However, multilocus genotyping information for G. duodenalis infecting NHPs in southwestern China is limited. In the present study, the prevalence and multilocus genotypes (MLGs of G. duodenalis in captive NHPs in southwestern China were determined. We examined 207 fecal samples from NHPs in Sichuan and Guizhou provinces, and 16 specimens were positive for G. duodenalis. The overall infection rate was 7.7%, and only assemblage B was identified. G. duodenalis was detect positive in northern white-cheeked gibbon (14/36, 38.9%, crab-eating macaque (1/60, 1.7% and rhesus macaques (1/101, 0.9%. Multilocus sequence typing based on beta-giardin (bg, triose phosphate isomerase (tpi and glutamate dehydrogenase (gdh revealed nine different assemblage B MLGs (five known genotypes and four novel genotypes. Based on a phylogenetic analysis, one potentially zoonotic genotype of MLG SW7 was identified in a northern white-cheeked gibbon. A high degree of genetic diversity within assemblage B was observed in captive northern white-cheeked gibbons in Southwestern China, including a potentially zoonotic genotype, MLG SW7. To the best of our knowledge, this is the first report using a MLGs approach to identify G. duodenalis in captive NHPs in Southwestern China.
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Beyatlı, Yavuz; Tulumoğlu, Şener
1991-01-01
Peyniraltı suyu tozundan altı farklı sentetik besi ortamı hazırlanmıştır. Bu besi ortamlarında 12 adet L. bulgaricus suşunun oluşturduğu laktik asit miktarları tespit edilmiştir. Katkılı besi ortamlarında oluşan laktik asit miktarları, katkısız besi ortamları ile kıyaslandığında daha fazla bulunmuştur. 12 adet L. bulgaricus suşu arasında en fazla laktik asit üretenlerin L. bulgaricus B1, L. bulgaricus B4 ve L. bulgaricus B11 suşları olduğu görülmüştür.
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77 FR 54933 - Government-Owned Inventions, Available for Licensing
2012-09-06
... Gameplay Combining Different Means of Control; NASA Case No.: LAR-18016-1: Wireless Temperature Sensor....: LAR-17958-1: Wireless Open-Circuit In-Plane Strain and Displacement Sensor Requiring No Electrical... for Determining Relative Motion Between Two Bodies; NASA Case No.: LAR-17877-1: Autonomous Slat-Cove...
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Mauritz, Femke A; Rinsma, Nicolaas F; van Heurn, Ernest L W; Sloots, Cornelius E J; Siersema, Peter D; Houwen, Roderick H J; van der Zee, David C; Masclee, Ad A M; Conchillo, José M; Van Herwaarden-Lindeboom, Maud Y A
2017-07-01
Esophageal intraluminal baseline impedance reflects the conductivity of the esophageal mucosa and may be an instrument for in vivo evaluation of mucosal integrity in children with gastroesophageal reflux disease (GERD). Laparoscopic antireflux surgery (LARS) is a well-established treatment option for children with proton pump inhibitory (PPI) therapy resistant GERD. The effect of LARS in children on baseline impedance has not been studied in detail. The aim of this study was to evaluate the effect of LARS on baseline impedance in children with GERD. This is a prospective, multicenter, nationwide cohort study (Dutch national trial registry: NTR2934) including 25 patients [12 males, median age 6 (range 2-18) years] with PPI-resistant GERD scheduled to undergo LARS. Twenty-four hour multichannel intraluminal impedance pH monitoring (MII-pH monitoring) was performed before and 3 months after LARS. Baseline impedance was evaluated during consecutive 2-h intervals in the 24-h tracings. LARS reduced acid exposure time from 8.5 % (6.0-16.2 %) to 0.8 % (0.2-2.8 %), p < 0.001. Distal baseline impedance increased after LARS from 2445 Ω (1147-3277 Ω) to 3792 Ω (3087-4700 Ω), p < 0.001. Preoperative baseline impedance strongly correlated with acid exposure time (r -0.76, p < 0.001); however, no association between symptomatic outcome and baseline impedance was identified. LARS significantly increased baseline impedance likely reflecting recovery of mucosal integrity. As the change in baseline impedance was not associated with the clinical outcome of LARS, other factors besides mucosal integrity may contribute to symptom perception in children with GERD.
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Kaneoka, Asako; Pisegna, Jessica M; Inokuchi, Haruhi; Ueha, Rumi; Goto, Takao; Nito, Takaharu; Stepp, Cara E; LaValley, Michael P; Haga, Nobuhiko; Langmore, Susan E
2018-04-01
The laryngeal adductor reflex (LAR) is an airway protective reflex that manifests as a brief vocal fold closure in response to laryngeal stimulation. This study examined if the absence of the LAR in response to touch delivered by a laryngoscope is associated with penetration/aspiration or pneumonia in patients with dysphagia. Inpatients at a teaching hospital with clinical symptoms of dysphagia were recruited upon referral to the otolaryngology clinic for a swallowing evaluation. Otolaryngologists observed the status of secretions and touched each arytenoid with the tip of the laryngoscope. The patients were then asked to swallow 3-5 mL grape gelatin and 3-5 mL colored water. All procedures were video-recorded. Two independent raters noted absence/presence of the LAR and penetration/aspiration of pharyngeal secretions, gelatin, and water on the recorded videos. A diagnosis of pneumonia during the patient's entire hospital stay was determined by a review of the hospital's medical records. Statistical analyses were performed using Fisher's exact test. Sixty-one patients were included. Twenty-one patients (34.5%) did not exhibit the LAR. No association was found between the absent LAR and penetration or aspiration. There was, however, a significant association between an absence of the LAR and pneumonia development. Patients with an absent LAR had 6.8 times the odds of developing pneumonia as compared to those with a present LAR (OR 6.75; 95% CI 1.76-25.96; p < 0.01). Using the LAR as a marker of laryngeal sensory function appears to be valuable for identifying patients at high risk of pneumonia.
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Deforestation in Viet Nam | IDRC - International Development ...
International Development Research Centre (IDRC) Digital Library (Canada)
Increased soil erosion, reduced water-storage capacity, changes in ... gibbons could have travelled from China to Singapore by swinging from tree to tree. ... IDRC congratulates first cohort of Women in Climate Change Science Fellows.
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DEFF Research Database (Denmark)
Wiberg, Merete
when they learn a disciplinary area and in this context design strategies for investigations and project writing. Due to the massification of education and research (Gibbons 1998, 2005) in most universities the tendency is that science and research have become oriented towards practice, partnerships...... is to discuss the role of theory of science in teaching and learning in the actual university context. It is to be discussed why a discussion of ontological complexity is relevant for the understanding of scientific work for both the researcher of today and the academics which are to apply research strategies......: European Educational Research Journal, Volume 6, no. 2, 2007 Nowotny, H. Scott, P., Gibbons, M. (2011). Re-Thinking Science, Cambridge: Polity Press Wittgenstein, L. (1984). Philosophische Untersuchungen. I: Wittgenstein, L. Werkausgabe Band 1. Frankfurt am Main: Suhrkamp....
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Directory of Open Access Journals (Sweden)
Hatice EKİNCİ
2013-03-01
Full Text Available Teachers, to fulfill the required qualifications of the teachingprofession, which could deal with the duties and responsibilitiesassociated with their self efficacy perceptions.This research aims to determine of the perceptions of self efficacythe teacher candidates of Mehmet Akif Ersoy University Faculty ofEducation Music, Art and Physical Education Teaching Department.Also it aims to relate of the perceptions of self efficacy in terms of class,gender and department variables.To determine teacher candidates’ perceptions of self-efficacy of theMusic, Art and Physical Education Department important todemonstrate an adequate and effective performance of their professionallife. In addition, the research, is thought to be important for thedevelopment of the results-oriented solutions.Research was conducted on a total of 224 teacher candidates ofthe Mehmet Akif Ersoy University, Faculty of Education, Music, Art andPhysical Education Department, attending the license of II, III and IV.classrooms.“Teachers' Self Efficacy Scale" is used as a data collection tool,whisch developed by Tschannen-Moran and Hoy (2001, made by Çapa,Çakıroğlu and Sarıkaya (2005, validity and reliability study for Turkishand attempted to describe teachers' perceptions of self-competence.The data was analyzed by using SPSS (version 20.0 ( SPSS Inc.,Chicago, USA. Frequency, percentage, correlation and MANOVAstatistics were used for the analysis of research findings.According to the findings from the research, there isn’t asignificant difference between levels of teacher candidates self efficacyaccording to the variables. In addition, teacher candidates findthemselves 75 percent of theself-sufficient have been identified. Öğretmenlerin özyeterlik algıları, öğretmenlik mesleğiningerektirdiği yeterlikleri yerine getirmeleri, görev ve sorumluluklarınınüstesinden gelebileceklerine olan inançları ile yakından ilişkilidir.Bu araştırma, Mehmet Akif Ersoy
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Directory of Open Access Journals (Sweden)
Taner Yıldız
2016-12-01
Full Text Available Bu çalışma, Samsun ili Bafra ilçesi ova kesiminde ikinci ürün silajlık mısır üreten işletmelerde toplam masraf, iş gücü gereksinimi ve iş başarılarının belirlenmesi amacıyla yapılmıştır. Elde edilen sonuçlara göre; toplam değişken ve sabit masraflar 2827,80 TL ha-1 ve 4224,60 TL ha-1 olarak hesaplanmıştır. Değişken ve sabit masrafların toplam üretim masrafları içerisindeki payları sırasıyla, %40,10 ve %59,90 olarak belirlenmiştir. Değişken masraflar içerisinde en yüksek payı gübreleme (%10,30 ve ilaçlama masrafları (%7,00 alırken; sabit masraflarda en yüksek payı ise arazi kiralama masrafı (%24,70 oluşturmuştur. En yüksek iş gücü gereksinimi hasat işlemlerinde (4,28 h ha-1 ve en düşük iş gücü gereksinimi ise ilaçlama işlemlerinde (2,35 h ha-1 ortaya çıkmıştır. İş başarıları bakımından en yüksek iş başarısı, nakliye işlemlerinde (0,53 ha h-1 elde edilmiştir.
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Directory of Open Access Journals (Sweden)
Kaya Yılmaz
2012-10-01
Full Text Available Özet: Kavramlar, düşünmenin ve öğrenmenin gerçekleştiği yer olan bilişin temel yapı taşlarını oluşturdukları için etkili ve anlamlı bir öğrenmenin gerçekleşmesinde önemli bir role sahiptirler. Ülkemizde yapılandırmacı yaklaşıma dayalı olarak 2004 yılında oluşturulan ilköğretim sosyal bilgiler öğretim programında kavram öğretim ve öğrenimine önemli bir yer verilmiştir. Öğretim programında kavramların giriş, gelişme ve pekiştirme seviyelerinin hangi sınıf düzeyinde verileceği özel olarak belirtilmiştir. Sosyal bilgiler dersinde kavram öğretim ve öğreniminde karşılaşılan en önemli sorunlardan birisi kavram yanılgılarıdır. İlköğretim sosyal bilgiler dersi tarih konularının öğretiminde önemli bir engel olarak karşımıza çıkan tarih kavram yanılgıları üzerine yapılmış yeterli çalışma bulunmamaktadır. Literatürdeki bu eksikliği gidermeyi hedefleyen bu çalışmada, sosyal bilgiler eğitimi çerçevesinde tarih konularının öğretiminde karşılaşılan kavram yanılgılarının tespit edilmesi, ortadan kaldırılması ve azaltılması hedeflenmiştir. Çalışmada nitel araştırma desenlerinden eylem araştırması kullanılmıştır. 6. Sınıf sosyal bilgiler dersi “Yeryüzünde Yaşam” Ünitesinde geçen ‘milat’, ‘yüzyıl’, ‘çağ’, ‘kronoloji’, ‘fetih’ ve ‘uygarlık’ kavramlarına ilişkin öğrencilerin yanılgılarını tespit etmek ve gidermek amacıyla kavram haritaları, kavram çarkı diyagramı, çalışma yaprağı, tarih şeridi, görüşme ve öğrenci günlükleri gibi çeşitli uygulamalar yapılmıştır. Verilerin çözümlenmesinde betimsel analiz yöntemi kullanılmıştır. Çalışma sonucunda öğrencilerin araştırılan kavramlara ilişkin birçok yanılgıya sahip oldukları, günümüz bakış açısıyla geçmişe baktıkları ve anakronizim sorunu yaşadıkları belirlenmiştir. Bu yanılgılar
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... Sport Follow us Caregiving Isn't a Solo Sport Leeza Gibbons is a leading TV talk show ... go it alone. Caregiving is not a solo sport. Identify who’s on your team. Delegate, forgive, regroup, ...
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Directory of Open Access Journals (Sweden)
Chunhua Zhang
Full Text Available With the growth of the low altitude remote sensing (LARS industry in recent years, their practical application in precision agriculture seems all the more possible. However, only a few scientists have reported using LARS to monitor crop conditions. Moreover, there have been concerns regarding the feasibility of such systems for producers given the issues related to the post-processing of images, technical expertise, and timely delivery of information. The purpose of this study is to showcase actual requests by farmers to monitor crop conditions in their fields using an unmanned aerial vehicle (UAV. Working in collaboration with farmers in northeastern Ontario, we use optical and near-infrared imagery to monitor fertilizer trials, conduct crop scouting and map field tile drainage. We demonstrate that LARS imagery has many practical applications. However, several obstacles remain, including the costs associated with both the LARS system and the image processing software, the extent of professional training required to operate the LARS and to process the imagery, and the influence from local weather conditions (e.g. clouds, wind on image acquisition all need to be considered. Consequently, at present a feasible solution for producers might be the use of LARS service provided by private consultants or in collaboration with LARS scientific research teams.
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Zhang, Chunhua; Walters, Dan; Kovacs, John M.
2014-01-01
With the growth of the low altitude remote sensing (LARS) industry in recent years, their practical application in precision agriculture seems all the more possible. However, only a few scientists have reported using LARS to monitor crop conditions. Moreover, there have been concerns regarding the feasibility of such systems for producers given the issues related to the post-processing of images, technical expertise, and timely delivery of information. The purpose of this study is to showcase actual requests by farmers to monitor crop conditions in their fields using an unmanned aerial vehicle (UAV). Working in collaboration with farmers in northeastern Ontario, we use optical and near-infrared imagery to monitor fertilizer trials, conduct crop scouting and map field tile drainage. We demonstrate that LARS imagery has many practical applications. However, several obstacles remain, including the costs associated with both the LARS system and the image processing software, the extent of professional training required to operate the LARS and to process the imagery, and the influence from local weather conditions (e.g. clouds, wind) on image acquisition all need to be considered. Consequently, at present a feasible solution for producers might be the use of LARS service provided by private consultants or in collaboration with LARS scientific research teams. PMID:25386696
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Zhang, Chunhua; Walters, Dan; Kovacs, John M
2014-01-01
With the growth of the low altitude remote sensing (LARS) industry in recent years, their practical application in precision agriculture seems all the more possible. However, only a few scientists have reported using LARS to monitor crop conditions. Moreover, there have been concerns regarding the feasibility of such systems for producers given the issues related to the post-processing of images, technical expertise, and timely delivery of information. The purpose of this study is to showcase actual requests by farmers to monitor crop conditions in their fields using an unmanned aerial vehicle (UAV). Working in collaboration with farmers in northeastern Ontario, we use optical and near-infrared imagery to monitor fertilizer trials, conduct crop scouting and map field tile drainage. We demonstrate that LARS imagery has many practical applications. However, several obstacles remain, including the costs associated with both the LARS system and the image processing software, the extent of professional training required to operate the LARS and to process the imagery, and the influence from local weather conditions (e.g. clouds, wind) on image acquisition all need to be considered. Consequently, at present a feasible solution for producers might be the use of LARS service provided by private consultants or in collaboration with LARS scientific research teams.
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International Journal of Arts and Humanities(IJAH) Ethiopia
African Journals Online (AJOL)
Nneka Umera-Okeke
to the rule of law (Gibbons, 2003), and researchers have been concerned with the roles ... to find out how this power manifests itself in courtroom interaction. ... traceable to sociology, ethnography, philosophy, applied linguistics and pragmatics ...
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ÖZTEKİN, Ekin
2016-01-01
Depresyonda yaygın olarak görülen araya girici anılar, bireyin geçmişte yaşadığı negatif yaşam olaylarının tekrarlayıcı ve rahatsız edici bir biçimde zihne gelmesi olarak tanımlanmaktadır. Araya girici anı kavramına ait deneyimsel özelliklerin diğer otobiyografik anılardan farklılaştığı ve duyguduruma bağlı değişimler gösterdiği bilinmektedir. Bu araştırmada literatürde çalışılmış olan tüm deneyimsel özelliklerin depresif ve depresif olmayan bireylerdeki araya girici anı görünümlerin...
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Directory of Open Access Journals (Sweden)
Ana Paula Zarzur
2010-02-01
Full Text Available A doença ou Mal de Parkinson se deve à deficiência dopaminérgica nos núcleos da base que geram alterações motoras. Comprometimento da comunicação verbal ocorre em 70 a 90% dos doentes. Existem poucas referências da aplicação da eletromiografia no estudo dos músculos laríngeos em pacientes com a doença de Parkinson. OBJETIVOS: Definir o padrão contrátil da musculatura intrínseca da laringe e sua correlação com a análise acústica vocal nos parkinsonianos. CASUÍSTICA E MÉTODO: Estudo prospectivo onde 26 adultos com o diagnóstico de Mal de Parkinson foram submetidos à eletromiografia laríngea e análise acústica vocal. Foram coletados potenciais de ação, tanto em repouso vocal quanto em fonação. Para a análise acústica da voz foram utilizados os programas VOXMETRIA® e GRAM 5.1.6®. RESULTADOS: O padrão eletromiográfico predominante no grupo estudo foi o de hipercontratibilidade (ou recrutamento aumentado durante repouso vocal que ocorreu em 73% dos indivíduos, sem que houvesse registro eletromiográfico de tremor. Quanto às características vocais, detectou-se a presença de tremor vocal no traçado do espectrograma (VOXMETRIA E GRAM e na avaliação perceptivo-auditiva em 69,5 % e 61 % dos sujeitos, respectivamente. CONCLUSÃO: O tremor vocal foi a característica acústica predominante no grupo estudado, sem que houvesse correlação eletromiográfica.Parkinson's disease (PD involves a progressive depletion of dopamine in the basal ganglia leading to motor alterations. Oral communication impairment occurs in 75% to 90% of patients and has been poorly studied. AIM: to asses laryngeal electromyography (LEMG patterns and correlate them to vocal analysis in patients with Parkinson's disease. MATERIALS AND METHODS: This is a prospective study. Twenty six adults with PD underwent laryngeal electromyography. Rest and phonation potentials were analyzed. VOXMETRIA® and GRAM 5.1.6. ® were used in acoustic analysis
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Directory of Open Access Journals (Sweden)
Hicran Hanım HALAÇ
2012-09-01
Full Text Available Most of the investigations which take hand Ottoman period of Turkey’s social and cultural history are limited to Istanbul. The works about dwelling deal with monumental buildings like palace or mansion. The investigations about the cities of architectural housing except for Istanbul are very restricted. . This situation is the same with the capital of Anatolian Seljuks, which is Konya. Beginning from Seljuk Empire, the historical monuments of Konya account for castles and mosques. There is no early period of housing which lasts contemporary. In case of absence of housing belongs to 18th century and even the beginning of 19th century; therefore, this causes generally accepted evaluations. The works which focus on architectural housing and domestic culture belonging to 19th century and before, this necessitate the exploitation of Ottoman documents composing of primary sources. This research article gives information about Konya’s two years between 1714 and 1715. This information is obtained from numbered 45 Şeriyye registry and from range information. In order to enlighten a part of the housing archtecture located in Konya using only road and floor information of range, the housing types of Konya and the housing typology of Konya at the beginning of the 18th century are determined. Osmanlı Dönemi Türkiye’sinin konut mimarisi ve domestik kültürüne ait araştırmaların çoğunlukla İstanbul odaklı gerçekleştiği, konutlara eğilen çalışmaların ise, saray ve köşk gibi anıtsal yapıları ele aldıkları görülmektedir. İstanbul dışındaki şehirlerin konut mimarisini ele alan çalışmaları oldukça azdır. Anadolu Selçuklularının başşehri olan Konya için de durum böyledir. Konya’nın Selçuklu Dönemi’ne kadar geriye giden tarihi eserlerini saray, kale, cami, türbe gibi anıtsal yapılar teşkil etmekte, günümüze gelebilmiş erken dönem konutları bulunmamaktadır. 18. yüzyıl, hatta erken 19. yüzyıl
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Directory of Open Access Journals (Sweden)
İbrahim COŞKUN
2013-09-01
reliability coefficient was calculated as .87. Analysis results are expressed in terms of percentage and frequency used for the quantification of qualitative data and direct extracts from the writings of students interpreted. Text examples of straight-line placement of text, the space between words, letter-spacing, letter format, suitable to produce, including six main categories of contiguity and the curvature examined. The findings of the study, the writing researchers, reading and writing documents and material authors,designers, classroom teachers and classroom teacher candidates will contribute important. Duygu ve düşüncelerin başarılı bir şekilde aktarılmasını sağlayankonuşma ve yazma becerileri, bir takım bilgi ve becerilerin birikiminigerektirmektedir. Bu bilgi ve becerilerin birikiminin temelleri iseilkokullarda atılmaktadır. İfade edici dil becerilerinden yazma becerisibireyin akademik, kültürel ve sosyal hayatında en çok kullandığıbecerilerdendir. Çocuklar, gelişim sürecinde olmakla birlikte, alıcı dilbecerilerinden dinlemeyi ve ifade edici dil becerilerinden konuşmayıokul öncesi dönemde, alıcı dil becerilerinden okuma ve ifade edici dilbecerilerinden yazmayı ise ilkokul döneminde kazanmaktadır. İlkokulbirinci sınıfta başlayan okuma yazma öğretim süreci şifreleme ve şifreyiçözme etkinliklerinden oluşmaktadır. Okunaklılığın kişiden kişiyedeğişmeyen evrensel kriterleri vardır. Bir yazı hangi dilde üretilmişolursa olsun bu kriterlere uyduğu sürece yazı hakkında “okunaklı”hükmü verilebilir. Buradan hareketle bu çalışmada Türkçe ve Bulgarcaokuma yazma öğretim sürecinde ilkokul birinci sınıf çocuklarınınürettiği yazıların okunaklılık kriterlerine incelenmesi amaçlanmıştır.Nitel araştırma modelinin durum çalışması tekniğine göre desenlenenbu araştırmada Türkiye’deki veriler 2012-2013 Öğretim Yılında Edirneilinde ilkokul birinci sınıfa devam eden 15 (9 erkek
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Validation of a Spanish Version of the Lille Apathy Rating Scale for Parkinson’s Disease
Directory of Open Access Journals (Sweden)
Rocio García-Ramos
2014-01-01
Full Text Available Introduction. To date, no rating scales for detecting apathy in Parkinson’s disease (PD patients have been validated in Spanish. For this reason, the aim of this study was to validate a Spanish version of Lille apathy rating scale (LARS in a cohort of PD patients from Spain. Participants and Methods. 130 PD patients and 70 healthy controls were recruited to participate in the study. Apathy was measured using the Spanish version of LARS and the neuropsychiatric inventory (NPI. Reliability (internal consistency, test-retest, and interrater reliability and validity (construct, content, and criterion validity were measured. Results. Interrater reliability was 0.93. Cronbach’s α for LARS was 0.81. The test-retest correlation coefficient was 0.97. The correlation between LARS and NPI scores was 0.61. The optimal cutoff point under the ROC curve was -14, whereas the value derived from healthy controls was -11. The prevalence of apathy in our population tested by LARS was 42%. Conclusions. The Spanish version of LARS is a reliable and useful tool for diagnosing apathy in PD patients. Total LARS score is influenced by the presence of depression and cognitive impairment. However, both disorders are independent identities with respect to apathy. The satisfactory reliability and validity of the scale make it an appropriate instrument for screening and diagnosing apathy in clinical practice or for research purposes.
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Directory of Open Access Journals (Sweden)
Antonio Nogueira de Almeida
2005-09-01
Full Text Available OBJETIVE: This paper reports the use of dexmedetomidine in three epileptic patients with cavernous angiomas that underwent awake surgery in order to map their speech areas. METHOD:Loading dose of dexmedetomidine varied from 1 mug/Kg/h to 3 mug/Kg/h over 20 minutes and maintenance dose from 0.4 mug/Kg/h to 0,8 mug/Kg/h. RESULTS: There was no occurrence of hemodynamic instability, convulsions or respiratory depression. Patients tolerated well the procedure. CONCLUSION: Dexmedetomidine was useful for awake craniotomy as it decreased patients’ level of consciousness but did not produce agitation. Laryngeal mask was not necessary to keep air ventilation.OBJETIVO: Este trabalho relata o uso de desmedetomidina em três pacientes com angiomas cavernosos próximos a área de linguagem e epilepsia que foram operados acordados para mapeamento cortical. MÉTODO: A dose de ataque de dexmedetomidina variou de 1 mig/Kg/h a 3 mig/Kg/h durante 20 minutos e dose de manutenção de 0,4 mig/Kg/h a 0,8 mig/Kg/h. RESULTADOS: Os pacientes toleraram bem o procedimento e não houve instabilidade hemodinâmica, convulsões ou depressão respiratória. CONCLUSÃO: Dexmedetomidina foi útil nas craniotomias com o paciente acordado para mapeamento cortical pois gerou sedação sem agitação. A máscara laríngea não foi necessária para manter a ventilação nesses pacientes.
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Energy Technology Data Exchange (ETDEWEB)
Ahmed, Salahuddin, E-mail: Salah.Ahmed@utoledo.edu [Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, OH (United States); Riegsecker, Sharayah; Beamer, Maria; Rahman, Ayesha; Bellini, Joseph V. [Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, OH (United States); Bhansali, Pravin; Tillekeratne, L.M. Viranga [Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, OH (United States)
2013-07-15
In the present study, we evaluated the effect of largazole (LAR), a marine-derived class I HDAC inhibitor, on tumor necrosis factor-α (TNF-α)-induced expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1), and matrix metalloproteinase-2 (MMP-2) activity. LAR (1–5 μM) had no adverse effect on the viability of RA synovial fibroblasts. Among the different class I HDACs screened, LAR (0.5–5 μM) inhibited the constitutive expression of HDAC1 (0–30%). Surprisingly, LAR increased class II HDAC [HDAC6] by ∼ 220% with a concomitant decrease in HDAC5 [30–58%] expression in RA synovial fibroblasts. SAHA (5 μM), a pan-HDAC inhibitor, also induced HDAC6 expression in RA synovial fibroblasts. Pretreatment of RA synovial fibroblasts with LAR further enhanced TNF-α-induced ICAM-1 and VCAM-1 expression. However, LAR inhibited TNF-α-induced MMP-2 activity in RA synovial fibroblasts by 35% when compared to the TNF-α-treated group. Further, the addition of HDAC6 specific inhibitor Tubastatin A with LAR suppressed TNF-α + LAR-induced ICAM-1 and VCAM-1 expression and completely blocked MMP-2 activity, suggesting a role of HDAC6 in LAR-induced ICAM-1 and VCAM-1 expression. LAR also enhanced TNF-α-induced phospho-p38 and phospho-AKT expression, but inhibited the expression of phospho-JNK and nuclear translocation of NF-κBp65 in RA synovial fibroblasts. These results suggest that LAR activates p38 and Akt pathways and influences class II HDACs, in particular HDAC6, to enhance some of the detrimental effects of TNF-α in RA synovial fibroblasts. Understanding the exact role of different HDAC isoenzymes in RA pathogenesis is extremely important in order to develop highly effective HDAC inhibitors for the treatment of RA. - Highlights: • Largazole enhances TNF-α-induced ICAM-1 and VCAM-1. • Largazole upregulates class II HDAC (HDAC6) in RA synovial fibroblasts. • Largazole also induces the expression of phospho-p38
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A simple proof of the recent generalizations of Hawking's black hole topology theorem
Energy Technology Data Exchange (ETDEWEB)
Racz, Istvan [RMKI, H-1121 Budapest, Konkoly Thege Miklos ut 29-33 (Hungary)], E-mail: iracz@sunserv.kfki.hu
2008-08-21
A key result in four-dimensional black hole physics, since the early 1970s, is Hawking's topology theorem assertion that the cross-sections of an 'apparent horizon', separating the black hole region from the rest of the spacetime, are topologically 2-spheres. Later, during the 1990s, by applying a variant of Hawking's argument, Gibbons and Woolgar could also show the existence of a genus-dependent lower bound for the entropy of topological black holes with negative cosmological constant. Recently, Hawking's black hole topology theorem, along with the results of Gibbons and Woolgar, has been generalized to the case of black holes in higher dimensions. Our aim here is to give a simple self-contained proof of these generalizations, which also makes their range of applicability transparent. (fast track communication)
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Directory of Open Access Journals (Sweden)
Cüneyt Güler
2017-01-01
Full Text Available The aim of this study was to investigate natural and anthropogenic processes governing the chemical composition of alkaline groundwater within a fractured rock (ophiolitic mélange aquifer underlying a seasonally inhabited headwater area in the Aladağlar Range (Adana, Turkey. In this aquifer, spatiotemporal patterns of groundwater flow and chemistry were investigated during dry (October 2011 and wet (May 2012 seasons utilizing 25 shallow hand-dug wells. In addition, representative samples of snow, rock, and soil were collected and analyzed to constrain the PHREEQC inverse geochemical models used for simulating water-rock interaction (WRI processes. Hydrochemistry of the aquifer shows a strong interseasonal variability where Mg–HCO3 and Mg–Ca–HCO3 water types are prevalent, reflecting the influence of ophiolitic and carbonate rocks on local groundwater chemistry. R-mode factor analysis of hydrochemical data hints at geochemical processes taking place in the groundwater system, that is, WRI involving Ca- and Si-bearing phases; WRI involving amorphous oxyhydroxides and clay minerals; WRI involving Mg-bearing phases; and atmospheric/anthropogenic inputs. Results from the PHREEQC modeling suggested that hydrogeochemical evolution is governed by weathering of primary minerals (calcite, chrysotile, forsterite, and chromite, precipitation of secondary minerals (dolomite, quartz, clinochlore, and Fe/Cr oxides, atmospheric/anthropogenic inputs (halite, and seasonal dilution from recharge.
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Demirkaya, Sevcan Karakoç; Aksu, Hatice; Özgür, Börte Gürbüz
2017-11-30
Risperidone has been widely used to control aggression and conduct disorder (CD) in youth; however, treatment compliance is a major problem in CD. Our aim is to evaluate the effectiveness and tolerability of long-acting risperidone (LAR) in treating nonadherent cases. The medical records of children and adolescents who had CD and were nonadherent to conventional drugs and psychosocial interventions (and therefore taking LAR) were reviewed. Informed consent on offlabel use of LAR was obtained from the parents. Clinical Global Impression (CGI) Severity (CGI-S) and CGI-Improvement scales were used and baseline and end points were compared. The study comprised 14 children and adolescents (5 girls, 9 boys). All had comorbid disorders: substance use disorder (n=8), attention deficit hyperactivity disorder (n=6), and major depression (n=2). Mean duration of LAR use was 3.1 months (1.5-8 months). We observed significant improvements in the baseline and endpoint CGI-S scores for CD in all but one patient (Z=-3.198; p ＜0.001). Only mild adverse effects were observed: weight gain (n=2), sedation (n=1), leg cramps (n=1), and increased appetite with no weight gain (n=1). LAR is effective and tolerable for patients with CD who can't be medicated with oral preparations due to nonadherence to treatment. Even short-term LAR use is effective to get compliance. As CD predicts numerous problems in adulthood, appropriate treatment is crucial. To our knowledge, this is the first study on LAR use in youth with CD. The use of LAR deserves careful consideration and further controlled studies are needed to confirm our findings.
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Sharif, Farkhondeh; Seddigh, Maryam; Jahanbin, Iran; Keshavarzi, Sareh
2015-01-01
Aging is associated with reduced quality and quantity of sleep. 50% of senior citizens living in the community and 70% of those living in nursing homes suffer from sleep disorders. Moreover, insomnia increases the risk of mortality and morbidity in older adults. We aimed to investigate the effect of aerobic exercise on quantity and quality of sleep among the elderly people referring to health centers of Lar city, southern Iran. We enrolled 60 elderly people whose age range was 60-75 years and (mean ±SD) age was (64.8±5.2). Participants were randomly assigned into two groups of 30 each (case group= 30 and control group=30). The patients in the case group participated in exercise trainings consisted of three one-hour sessions per week for 12 consecutive weeks. Sleep quantity and quantity in the participants was evaluated before and after intervention using Pittsburgh Sleep Quality Index (PSQI). Independent t-test showed that sleep quality score was improved by 44.46% in the case group (pelderly. It could also be used as a cost effective and long lasting method of therapy with no side effect which could be used for the treatment of insomnia in older people.
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Directory of Open Access Journals (Sweden)
Raquel de Cássia Ferro Fagundes
2011-03-01
Full Text Available A tuberculose é uma doença que esteve presente durante toda história. No século XIX o bacilo causador da doença foi descoberto e denominado bacilo de Koch. A tuberculose laríngea é uma das complicações da tuberculose pulmonar, e o sintoma mais comum é a rouquidão, decorrente ao processo cicatricial das lesões laríngeas. Sendo assim, o objetivo deste estudo foi verificar a efetividade da fonoterapia em um caso de disfonia pós-tratamento medicamentoso da tuberculose laríngea. A metodologia utilizada foi o estudo de caso do paciente J.O.B.S, 39 anos, gênero masculino, recepcionista de hotel, com jornada de oito diárias e ex-fumante, que trouxe como queixas principais rouquidão, cansaço e falta de ar durante a fala. Após as avaliações fonoaudiológica e otorrinolaringológica iniciaram-se as sessões de fonoterapia, com objetivo de diminuir a tensão à fonação, induzir o afastamento de pregas vestibulares, favorecer a mobilidade das pregas vocais, instaurar a respiração com apoio abdominal e melhorar a coordenação pneumofonoarticulatória. Após as 12 sessões previstas na metodologia desse estudo, diversos parâmetros vocais apresentaram melhoras, dentre eles a diminuição da tensão à fonação, respiração com apoio abdominal, melhoria da coordenação pneumofonoarticulatória, aumento da loudness e diminuição do ataque vocal brusco, que refletiram em uma emissão com menor esforço e mais aceita socialmente. A terapia fonoaudiológica, apesar das limitações decorrentes aos processos cicatriciais das lesões, mostrou-se importante no caso apresentado e o paciente ficou satisfeito com os resultados obtidos, os quais refletiram de forma positiva na comunicação oral e no convívio social do paciente.Tuberculosis is a disease that has been present throughout history. In the XIX century the agent that causes the disease was discovered and named mycobacterium tuberculosis. Laryngeal tuberculosis is one of the
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Contribution of a Liquid Argon TPC to T2K Neutrino Experiment
Meregaglia, A.; Rubbia, A.
2006-08-01
A 2 km LAr detector would be an important asset for the T2K experiment. Different physics scenarios are considered and for each one the role of a LAr TPC in enhancing the ultimate sensitivity on theta 13 is studied. The large sample of neutrino interactions in the GeV region would provide crucial information for the study of different types of reactions and of nuclear effects, whereas the inner target would give a direct measurement of the cross sections ratio between Water and Argon. Such a detector would also be an important milestone for the LAr TPC technique providing an extremely valuable experience for future large LAr detectors.
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Antidepressants for Children and Teens
... et al. Antidepressant drugs and the risk of suicide in children and adolescents. Pediatric Drugs. 2014;16:115. Gibbons RD, et al. Antidepressant treatment and suicide attempts and self-inflicted injury in children and adolescents. Pharmacoepidemiology and Drug Safety. 2015;24: ...
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Directory of Open Access Journals (Sweden)
Marcius Vinícius M. Maranhão
2002-07-01
Full Text Available JUSTIFICATIVA E OBJETIVOS: Embora as disfonias pós-operatórias sejam freqüentemente associadas a complicações da intubação e extubação traqueal, outras causas podem estar envolvidas, inclusive cirúrgicas. O objetivo deste artigo é relatar um caso de disfonia no pós-operatório tardio, decorrente de paralisia de prega vocal esquerda, devido à lesão do nervo laríngeo recorrente esquerdo, durante cirurgia de ligadura do canal arterial. RELATO DO CASO: Paciente do sexo feminino, 6 anos, estado físico ASA II, peso 18.800 g, submetida à cirurgia para ligadura do canal arterial. Recebeu como medicação pré anestésica, midazolam (0,8 mg.kg-1, 60 minutos antes da cirurgia. A indução e a manutenção da anestesia foram feitas com sevoflurano, alfentanil e pancurônio. A dissecção do canal arterial foi realizada com dificuldade. No 4º dia do pós-operatório apresentou disfonia persistente. A videolaringoscopia mostrou paralisia de prega vocal esquerda e pequena fenda paramediana. CONCLUSÕES: Pela sua íntima relação com o canal arterial, o nervo laríngeo recorrente esquerdo pode ser lesado, durante a cirurgia corretiva, principalmente quando existem dificuldades na dissecção e ligadura do canal arterial. Diferentemente das disfonias decorrentes da intubação e extubação traqueal, surgem mais tardiamente e permanecem por longos períodos, podendo inclusive serem irreversíveis.JUSTIFICATIVA Y OBJETIVOS: Aun cuando las disfonias pós-operatorias sean frecuentemente asociadas a complicaciones de la intubación y extubación traqueal, otras causas pueden estar envolvidas, incluso quirúrgicas. El objetivo de este artículo es relatar un caso de disfonía en el pós-operatorio tardío, decurrente de parálisis de pliegue vocal izquierdo, debido a lesión del nervio laríngeo recurrente izquierdo, durante cirugía de ligadura del canal arterial. RELATO DE CASO: Paciente del sexo femenino, 6 años, estado físico ASA II, peso 18
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Meregaglia, Anselmo
2006-09-01
A 2 km LAr detector would be an important asset for the T2K experiment since it would play an important part in reducing the systematics and improving the ultimate θ sensitivity. It would also be an important milestone for the LAr TPC technique, providing in-situ R&D and paving the way for future large LAr detectors. Its main features are discussed in this talk.
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Etzold, Sabrina; MacKenzie, Donald A; Jeffers, Faye; Walshaw, John; Roos, Stefan; Hemmings, Andrew M; Juge, Nathalie
2014-05-01
The mucus layer covering the gastrointestinal tract is the first point of contact of the intestinal microbiota with the host. Cell surface macromolecules are critical for adherence of commensal bacteria to mucus but structural information is scarce. Here we report the first molecular and structural characterization of a novel cell-surface protein, Lar_0958 from Lactobacillus reuteri JCM 1112(T) , mediating adhesion of L. reuteri human strains to mucus. Lar_0958 is a modular protein of 133 kDa containing six repeat domains, an N-terminal signal sequence and a C-terminal anchoring motif (LPXTG). Lar_0958 homologues are expressed on the cell-surface of L. reuteri human strains, as shown by flow-cytometry and immunogold microscopy. Adhesion of human L. reuteri strains to mucus in vitro was significantly reduced in the presence of an anti-Lar_0958 antibody and Lar_0958 contribution to adhesion was further confirmed using a L. reuteri ATCC PTA 6475 lar_0958 KO mutant (6475-KO). The X-ray crystal structure of a single Lar_0958 repeat, determined at 1.5 Å resolution, revealed a divergent immunoglobulin (Ig)-like β-sandwich fold, sharing structural homology with the Ig-like inter-repeat domain of internalins of the food borne pathogen Listeria monocytogenes. These findings provide unique structural insights into cell-surface protein repeats involved in adhesion of Gram-positive bacteria to the intestine. © 2014 John Wiley & Sons Ltd.
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Directory of Open Access Journals (Sweden)
Jan-Shun Chang
2016-06-01
Full Text Available The aim of the present study was to evaluate the serial changes of GH and IGF-1 in seven patients with naïve, active acromegaly following presurgical treatment of the somatostatin analog pasireotide long-acting release (LAR and octreotide LAR. The patients were treated with pasireotide LAR with or without octreotide LAR for two years and underwent transsphenoidal adenomectomy. After treatment with the somatostatin analogs, the surgical cure rate was similar to that in patients who underwent transsphenoidal surgery alone. Diabetes insipidus was not identified in any patients after the operation. Pasireotide LAR was effective on GH as well as IGF-1 suppression and tumor size decreasing when used as the primary therapy. Future large-population studies to investigate the surgical curative rate after presurgical treatment with somatostatin analogs in patients with acromegaly and macroadenomas close to the cavernous sinus are warranted. However, that hyperglycemia developed following pre-surgical treatment with pasireotide should take into consideration.
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International Nuclear Information System (INIS)
Meregaglia, Anselmo
2006-01-01
A 2 km LAr detector would be an important asset for the T2K experiment since it would play an important part in reducing the systematics and improving the ultimate θ 13 sensitivity. It would also be an important milestone for the LAr TPC technique, providing in-situ R and D and paving the way for future large LAr detectors. Its main features are discussed in this talk
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Faggiano, Antongiulio; Tavares, Lidice Brandao; Tauchmanova, Libuse; Milone, Francesco; Mansueto, Gelsomina; Ramundo, Valeria; De Caro, Maria Laura Del Basso; Lombardi, Gaetano; De Rosa, Gaetano; Colao, Annamaria
2008-11-01
In patients with multiple endocrine neoplasia type 1 (MEN1), expression of somatostatin receptor (SST) in parathyroid adenomas and effectiveness of therapy with somatostatin analogues on primary hyperparathyroidism (PHP) have been scarcely investigated. To evaluate the effects of depot long acting octreotide (OCT-LAR) in patients with MEN1-related PHP. Eight patients with a genetically confirmed MEN1, presenting both PHP and duodeno-pancreatic neuroendocrine tumours (NET), were enrolled. The initial treatment was OCT-LAR 30 mg every 4 weeks. This therapy was established to stabilize the duodeno-pancreatic NET before to perform parathyroidectomy for PHP. Before OCT-LAR therapy, a SST scintigraphy was performed in all patients. SST subtype 2A immunohistochemistry was performed on parathyroid tumour samples from three patients undergone parathyroidectomy after OCT-LAR therapy. Serum concentrations of PTH, calcium and phosphorus as well as the 24-h urine calcium : creatinine ratio and the renal threshold phosphate concentration were evaluated before and after OCT-LAR. After OCT-LAR therapy, hypercalcaemia and hypercalciuria normalized in 75% and 62.5% of patients, respectively, and serum phosphorus and renal threshold phosphate significantly increased. Serum PTH concentrations significantly decreased in all patients and normalized in two of them. SST subtype 2A immunostaining was found in all parathyroid adenomas investigated, while SST scintigraphy showed a positive parathyroid tumour uptake in three of eight patients (37.5%). Six months of OCT-LAR therapy controlled hypercalcaemia and hypercalciuria in two-thirds of patients with MEN1-related PHP. Direct OCT-LAR effects mediated by binding to SST expression on parathyroid tumour cells are likely the main mechanism to explain the activity of this compound on calcium and phosphorus abnormalities in MEN1 PHP.
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inverse gaussian model for small area estimation via gibbs sampling
African Journals Online (AJOL)
ADMIN
For example, MacGibbon and Tomberlin. (1989) have considered estimating small area rates and binomial parameters using empirical Bayes methods. Stroud (1991) used hierarchical Bayes approach for univariate natural exponential families with quadratic variance functions in sample survey applications, while Chaubey ...
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2012-09-27
... Collection; Pell Grants and the Payment of Unemployment Benefits to Individuals in Approved Training... Pell Grants and the payment of unemployment benefits to individuals in approved training. DATES... November 26, 2012. ADDRESSES: Submit written comments to Scott Gibbons, Office of Unemployment Insurance...
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Phantom Behavioral Assimilation Effects : Systematic Biases in Social Comparison Choice Studies
Marsh, Herbert W.; Seaton, Marjorie; Kuyper, Hans; Dumas, Florence; Huguet, Pascal; Regner, Isabelle; Buunk, Abraham P.; Monteil, Jean-Marc; Gibbons, Frederick X.
Consistent with social comparison theory (SCT), Blanton, Buunk, Gibbons, and Kuyper (1999) and Huguet, Dumas, Monteil, and Genestoux (2001) found that students tended to choose comparison targets who slightly outperformed them (i.e., upward comparison choices), and this had a beneficial effect on
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Byron, C D; Granatosky, M C; Covert, H H
2017-12-01
Pygathrix is an understudied Asian colobine unusual among the Old World monkeys for its use of arm-swinging. Little data exists on the anatomy and mechanics of brachiation in this genus. Here, we consider this colobine to gain insight into the parallel evolution of suspensory behavior in primates. This study compares axial and appendicular morphological variables of Pygathrix with other Asian colobines. Additionally, to assess the functional consequences of Pygathrix limb anatomy, kinematic and kinetic data during arm-swinging are included to compare the douc monkey to other suspensory primates (Ateles and Hylobates). Compared to more pronograde species, Pygathrix and Nasalis share morphology consistent with suspensory locomotion such as its narrower scapulae and elongated clavicles. More distally, Pygathrix displays a gracile humerus, radius, and ulna, and shorter olecranon process. During suspensory locomotion, Pygathrix, Ateles, and Hylobates all display mechanical convergence in limb loading and movements of the shoulder and elbow, but Pygathrix uses pronated wrist postures that include substantial radial deviation during arm-swinging. The adoption of arm-swinging represents a major shift within at least three anthropoid clades and little data exist about its transition. Across species, few mechanical differences are observed during arm-swinging. Apparently, there are limited functional solutions to the challenges associated with moving bimanually below branches, especially in more proximal forelimb regions. Morphological data support this idea that the Pygathrix distal forelimb differs from apes more than its proximal end. These results can inform other studies of ape evolution, the pronograde to orthograde transition, and the convergent ways in which suspensory locomotion evolved in primates. © 2017 Wiley Periodicals, Inc.
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Imazato, Harunobu; Mizoguchi, Shun'ya; Yata, Masaya
We consider the Gibbons-Hawking metric for a three-dimensional periodic array of multi-Taub-NUT centers, containing not only centers with a positive NUT charge but also ones with a negative NUT charge. The latter are regarded as representing the asymptotic form of the Atiyah-Hitchin metric. The periodic arrays of Taub-NUT centers have close parallels with ionic crystals, where the Gibbons-Hawking potential plays the role of the Coulomb static potential of the ions, and are similarly classified according to their space groups. After a periodic identification and a Z2 projection, the array is transformed by T-duality to a system of NS5-branes with the SU(2) structure, and a further standard embedding yields, though singular, a half-BPS heterotic 5-brane background with warped compact transverse dimensions. A discussion is given on the possibility of probing the singular geometry by two-dimensional gauge theories.
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Gao, Chong-han; Wang, Fei; Jiang, Rong; Zhang, Jin; Mou, Huamin; Yin, Yue-hui
2011-07-05
The aim of the present study was to determine and quantify the cardiac autonomic innervation of the canine atria and pulmonary vein. Tissue specimens were taken from the canine pulmonary veins (PVs), posterior left atrium (PLA), left atrial roof (LAR), anterior left atrium (ALA), interatrial septum (IAS), and left atrial appendage (LAA) respectively for immunohistochemical analysis and nerve density determination. Both sympathetic and parasympathetic nerve densities decreased in the order: PLA>PV>IAS>LAR>ALA>LAA. For sympathetic nerve, multiple comparisons between any two regions showed a significant difference (PIAS vs. LAR, and LAR vs. ALA; for parasympathetic nerve, all the differences between any pair of regions were statistically significant (PIAS vs. LAR, LAR vs. ALA, and ALA vs. LAA. For both nerve types, there was a decreasing gradient of nerve densities from the external to internal layer (P<0.001, for each comparisons). Nerve density at the ostia for either nerve type was significantly higher than at the distal segments of PVs (P<0.001). In summary, the LA and PVs are innervated by sympathetic and parasympathetic nerves in a regionally heterogeneous way, which may be important for the pathophysiological investigation and ablation therapy of atrial fibrillation (AF). Copyright © 2011 Elsevier B.V. All rights reserved.
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Directory of Open Access Journals (Sweden)
İlknur MAYA
2013-07-01
aninstitutional infrastructure, ethic values of an institution, questioningone’s conscience, values education and character education, andregular supervision. It was found that academicians experienced ethicaldilemmas between educational activities and research activities,between their work at university and willingness to work in privatesector, and between administrators’ pressures and their personal valuesin fulfilling their duties; respectively. Araştırmada, akademisyenlerin gerçekleştirdikleri eğitim-öğretim, araştırma ve topluma hizmet gibi etkinliklerde meslek ahlakına aykırı olarak algıladıkları davranışların neler olduğunun, nedenlerinin ve nasıl önlenebileceğinin belirlenmesi amaçlanmaktadır. Ayrıca çalışmada, akademisyenlerin yaşadıkları etik ikilemlerin neler olduğunun saptanmasına çalışılmaktadır. Araştırmada nitel araştırma yöntemlerinden yarı yapılandırılmış görüşme tekniği kullanılmıştır. Çalışma grubunu, Çanakkale Onsekiz Mart Üniversitesi Eğitim Fakültesinde görev yapmakta olan yüz akademisyenden kartopu örnekleme yoluyla seçilmiş elli kişi oluşturmaktadır. Verilerin analizinde, içerik analizi türlerinden tümevarımcı analiz kullanılmıştır. Akademisyenlerin meslek ahlakına aykırı olarak algıladıkları davranışlar, en çok eğitim-öğretim işleri daha sonra araştırma işlerinde görülmektedir. Akademisyenler, eğitim-öğretim işleri bakımından en çok mazeretsiz ders yapmamak, mazeretsiz derse geç girmek / dersten erken çıkmak, dersi etkili ve nitelikli olarak yürütmemek, üniversite dışında çalışma nedeniyle üniversitedeki sorumluluklarını yerine getirmemek ve öğrencilere eşit / adil davranmamak davranışlarını meslek ahlakına aykırı bulmaktadır. Akademisyenler, araştırma işleri bakımından en çok araştırmada alıntı ve kaynakları doğru vermemek, nitelikli ve özgün araştırmalar yapmamak ve araştırma verileri üzerinde oynamak
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Lifescience Database Archive (English)
Full Text Available urotrypsin OS=Saguinus labiatus GN=PRSS12... 35 0.31 sp|Q5G268|NETR_HYLLE Neurotr...Y Neurotrypsin OS=Pongo pygmaeus GN=PRSS12 PE... 32 3.5 sp|O13817|SEC7C_SCHPO Protein transport protein sec7...3 OS=Schizos... 31 4.5 sp|Q5G267|NETR_MACMU Neurotrypsin OS=Macaca mulatta GN=PRSS12...HUMAN Forkhead box protein J3 OS=Homo sapiens GN... 30 7.7 >sp|Q5G265|NETR_SAGLB Neurotrypsin OS=Saguinus labiatus GN=PRSS12...YPHYLPTEQRHRRTRPPPPLPRFPRPPRALPALRPHALQAGHTP 86 >sp|Q5G268|NETR_HYLLE Neurotrypsin OS=Hylobates leucogenys GN=PRSS12
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KURU, Nilgün
2010-01-01
Koroner Arter Hastalığı (KAH) gelişmiş ülkelerde olduğu gibi ülkemizde de gerek morbidite gerekse mortalitenin en önemli nedenidir. KAH'ın yaşam süresi ve kalitesi üzerindeki olumsuz etkisi, maddi ve manevi maliyetlerin yüksekliği düşünüldüğünde yaşam biçimlerini değiştirmeye yönelik koruyucu programların önemi daha iyi anlaşılacaktır. Bireylere olumlu sağlık davranışı kazandırma programları düzenlenmeden önce, bireylerin davranışlarını etkileyen etmenlerin ve bir davranışı yap...
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Ptok, M; Schroeter, S
2016-03-01
The laryngeal adductor reflex (LAR), a reflexive vocal fold closing mechanism, includes an early, probably di- or oligosynaptic ipsilateral LAR1- and a late ipsilateral and contralateral LAR2 polysynaptic component. In a clinical evaluation of dysphagia the LAR can be triggered by air pulses or tactile stimuli and typically assessed only qualitatively. The development and construction of a device that can selectively shoot very small water droplets (microdroplet impulse testing MIT). The MIT device has a water reservoir with an infinitely adjustable pressure. The opening period of the piezo-electrically operated valve determines the droplet size. With a high-speed camera system, the change in the airspeed of the drop can be determined, depending on the set water reservoir pressure. With the knowledge of the droplet size, the shooting speed and the estimation of the distance between the valve and laryngeal mucosa or airspeed can be determined the muzzle energy. By mounting the MIT device to a high speed glottography system, the time between the impact of the droplet on the laryngeal mucosa and the start of the laryngeal adduction, the LAR latency can be determined using an image by image evaluation. In dysphagia with penetration or aspiration it is presumed that the protective function of the larynx is no longer adequately ensured. The MIT-LAR device provides a valid and reliable method to assess LAR quantitatively. Furthermore, it holds the promise of being a simple to handle method that can be used clinically for routine diagnostics.
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Directory of Open Access Journals (Sweden)
R. Casero
2010-06-01
Full Text Available La leishmaniosis es una parasitosis de evolución crónica; en Argentina, sus agentes etiológicos principales pertenecen al complejo Leishmania (Viannia braziliensis, habitualmente asociado a lesiones cutáneas y mucocutáneas. Informamos en este trabajo un caso de leishmaniosis laríngea en un hombre de 29 años procedente de Jujuy, quien a raíz de múltiples subdiagnósticos portaba esta parasitosis desde hacía 20 años. En el año 2008 este paciente consulta por disfonía crónica y trastornos en las vías aéreas superiores, refiere que fue sometido a terapias con tuberculostáticos, antifúngicos y corticoides desde 2002. Diferentes biopsias y fibroscopías revelaron los siguientes diagnósticos: laringitis granulomatosa inespecífica, laringitis compatible con tuberculosis, laringitis compatible con histoplasmosis, linfoma Natural Killer extraganglionar a células pequeñas. Finalmente, estudios realizados en nuestro hospital demostraron la presencia de una laringe granulomatosa en toda su extensión, amastigotes intra y extracelulares de Leishmania spp., ausencia de formas compatibles con Micobacterias e Histoplasma, y laringitis crónica vinculable a Leishmania spp. El paciente realizó tratamiento con antimoniato de N-metil-glucamina y demostró una muy buena evolución clínica tras ser examinado 2 meses después. Si bien la leishmaniosis laríngea como lesión única no es la presentación prevalente de esta zoonosis, su estudio amerita especial atención en pacientes tratados con corticoides, pues esto evitará un diagnóstico tardío y las mayores consecuencias asociadas a la morbimortalidad propia de esta parasitosis.Leishmaniosis is a chronic parasitic disease, which in Argentina is mainly caused by protozoa belonging to the Leishmania (Viannia braziliensis complex, leading to cutaneous and mucosal pathologies. We report a rare case of laryngeal leishmaniosis in a 29 year-old man from Jujuy province, Argentina, who had been
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Seaton, M.; Marsh, H.W.; Dumas, F.; Huguet, P.; Monteil, J.M.; Regner, I.; Blanton, H; Buunk, Abraham P.; Gibbons, F.X; Kuyper, H.; Suls, J; Wheeler, L
Blanton, Buunk, Gibbons, and Kuyper (1999) and Huguet, Dumas, Monteil, and Genestoux (2001) found that children nominated a social comparison target who slightly outperformed them in class with a beneficial effect on course grades - an assimilation effect, but with no effects on self-evaluation.
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Düşük Erüsik Asitli Kolza Tohumu ve Yağlarının Bazı Özellikleri Üzerine Araştırmalar
Directory of Open Access Journals (Sweden)
Aziz Tekin
2015-02-01
Full Text Available Bu çalışmada, düşük erüsik asitli kolza tohumu ve yağlarının bazı özellikleri araştırılmıştır. Bu amaçla ondört farklı kolza çeşidi kullanılmıştır. Elde edilen bulgulara göre; kolza tohumlarında rutubet oranı %4.57-5.64, bin tane ağırlığı kurumaddede 2.51-6.18 g, ham selüloz oranı yağsız kurumaddede %11.54-18.17, protein oranı kurumaddede %17.16-25.26 ve yağ oranı kurumaddede %33.45-49.50 arasındadır. Tohumlardan petrol eteri ekstraksiyonuyla elde edilen yağlarda ise özgül ağırlık 0.9150-0.9265, kırılma indisi 1.4685-1.4721, serbest yağ asitleri %0.22-0.59, peroksit sayısı 3.11-8.24 MeO2/kg, iyot sayısı 102.0-115.1 sabunlaşma sayısı 178-185 ve sabunlaşmayan madde miktarı %0.35-0.71 arasında bulunmuştur.
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Energy Technology Data Exchange (ETDEWEB)
Tamura, M; Shirato, H [Department of Radiation Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido (Japan); Ito, Y [Department of Biostatistics, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido (Japan); Sakurai, H; Mizumoto, M; Kamizawa, S [Proton Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki (Japan); Murayama, S; Yamashita, H [Proton Therapy Division, Shizuoka Cancer Center Hospital, Nagaizumi, Shizuoka (Japan); Takao, S; Suzuki, R [Department of Medical Physics, Hokkaido University Hospital, Sapporo, Hokkaido (Japan)
2016-06-15
Purpose: To examine how much lifetime attributable risk (LAR) as an in silico surrogate marker of radiation-induced secondary cancer would be lowered by using proton beam therapy (PBT) in place of intensity modulated x-ray therapy (IMXT) in pediatric patients. Methods: From 242 pediatric patients with cancers who were treated with PBT, 26 patients were selected by random sampling after stratification into four categories: a) brain, head, and neck, b) thoracic, c) abdominal, and d) whole craniospinal (WCNS) irradiation. IMXT was re-planned using the same computed tomography and region of interest. Using dose volume histogram (DVH) of PBT and IMXT, the LAR of Schneider et al. was calculated for the same patient. The published four dose-response models for carcinoma induction: i) full model, ii) bell-shaped model, iii) plateau model, and ix) linear model were tested for organs at risk. In the case that more than one dose-response model was available, the LAR for this patient was calculated by averaging LAR for each dose-response model. Results: Calculation of the LARs of PBT and IMXT based on DVH was feasible for all patients. The mean±standard deviation of the cumulative LAR difference between PBT and IMXT for the four categories was a) 0.77±0.44% (n=7, p=0.0037), b) 23.1±17.2%,(n=8, p=0.0067), c) 16.4±19.8% (n=8, p=0.0525), and d) 49.9±21.2% (n=3, p=0.0275, one tailed t-test), respectively. The LAR was significantly lower by PBT than IMXT for the the brain, head, and neck region, thoracic region, and whole craniospinal irradiation. Conclusion: In pediatric patients who had undergone PBT, the LAR of PBT was significantly lower than the LAR of IMXT estimated by in silico modeling. This method was suggested to be useful as an in silico surrogate marker of secondary cancer induced by different radiotherapy techniques. This research was supported by the Translational Research Network Program, JSPS KAKENHI Grant No. 15H04768 and the Global Institution for
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International Nuclear Information System (INIS)
Tamura, M; Shirato, H; Ito, Y; Sakurai, H; Mizumoto, M; Kamizawa, S; Murayama, S; Yamashita, H; Takao, S; Suzuki, R
2016-01-01
Purpose: To examine how much lifetime attributable risk (LAR) as an in silico surrogate marker of radiation-induced secondary cancer would be lowered by using proton beam therapy (PBT) in place of intensity modulated x-ray therapy (IMXT) in pediatric patients. Methods: From 242 pediatric patients with cancers who were treated with PBT, 26 patients were selected by random sampling after stratification into four categories: a) brain, head, and neck, b) thoracic, c) abdominal, and d) whole craniospinal (WCNS) irradiation. IMXT was re-planned using the same computed tomography and region of interest. Using dose volume histogram (DVH) of PBT and IMXT, the LAR of Schneider et al. was calculated for the same patient. The published four dose-response models for carcinoma induction: i) full model, ii) bell-shaped model, iii) plateau model, and ix) linear model were tested for organs at risk. In the case that more than one dose-response model was available, the LAR for this patient was calculated by averaging LAR for each dose-response model. Results: Calculation of the LARs of PBT and IMXT based on DVH was feasible for all patients. The mean±standard deviation of the cumulative LAR difference between PBT and IMXT for the four categories was a) 0.77±0.44% (n=7, p=0.0037), b) 23.1±17.2%,(n=8, p=0.0067), c) 16.4±19.8% (n=8, p=0.0525), and d) 49.9±21.2% (n=3, p=0.0275, one tailed t-test), respectively. The LAR was significantly lower by PBT than IMXT for the the brain, head, and neck region, thoracic region, and whole craniospinal irradiation. Conclusion: In pediatric patients who had undergone PBT, the LAR of PBT was significantly lower than the LAR of IMXT estimated by in silico modeling. This method was suggested to be useful as an in silico surrogate marker of secondary cancer induced by different radiotherapy techniques. This research was supported by the Translational Research Network Program, JSPS KAKENHI Grant No. 15H04768 and the Global Institution for
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DEFF Research Database (Denmark)
Ottesen, L.H.; Aagaard, Niels Kristian; Kiszka-Kanowitz, M.
2001-01-01
variable effects. Twenty-five cirrhotic patients with portal hypertension were randomized in a double-blind design to placebo or a single subcutaneous dose of a long-acting formulation of octreotide (octreotide-LAR) (20 mg). Renal function tests were performed before dosing and repeated after 30 days...... with octreotide-LAR. It is concluded that in spite of increased arterial pressure, octreotide-LAR has no significant effect on renal hemodynamics and tubular function in clinically stable cirrhotic patients with portal hypertension....
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SEZGİN, Ferudun; KILINÇ, Ali Çağatay
2015-01-01
Bu çalışmanın amacı, ilköğretim okulu öğretmenlerinin tükenmişlik düzeyleri ile örgütsel vatandaşlık davranışları arasındaki ilişkileri incelemektir. Araştırmaya Kocaeli ili merkezinde yer alan 14 ilköğretim okulunda görevli 269 öğretmen katılmıştır. Öğretmenlerin tükenmişlik düzeylerinin belirlenmesi için “Maslach Tükenmişlik Envanteri” ve örgütsel vatandaşlık düzeylerinin belirlenmesi için “Örgütsel Vatandaşlık Ölçeği” kullanılmıştır. Verilerin analizinde Pearson momentler çarpımı korelasyo...
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In-situ measurement of the light attenuation in liquid argon in the GERDA cryostat
Energy Technology Data Exchange (ETDEWEB)
Schneider, Birgit [TU Dresden, Institut fuer Kern- und Teilchenphysik (Germany); Collaboration: GERDA-Collaboration
2016-07-01
GERDA is an experiment searching for neutrinoless double beta decay in {sup 76}Ge. It operates the enriched germanium detectors bare in liquid argon (LAr), which serves both as a coolant and a shield for external radiation. Phase II of GERDA aims for an exposure of 100 kg . yr with a background index (BI) of 10{sup -3} cts/(kg . yr . keV). One of the major improvements to further reduce the BI comes from the instrumentation of the LAr to readout its scintillation light. The attenuation of the scintillation light in LAr limits the effective active volume of the LAr veto and is therefore a key parameter to characterize the instrumentation. In order to measure the light attenuation in LAr, a setup was designed that could be deployed directly into the GERDA cryostat. This setup contains a movable beta source and a PMT to detect the scintillation light at different distances. The talk will present the acquired data as well as a detailed description of the performed analysis technique and the current results.
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Weertman, A; ArntZ, A; Dreessen, L; van Velzen, C; Vertommen, S
2003-01-01
This study examined the short-interval test-retest reliability of the Structured Clinical Interview (SCID-II: First, Spitzer, Gibbon, & Williams, 1995) for DSM-IV personality disorders (PDs). The SCID-II was administered to 69 in- and outpatients on two occasions separated by 1 to 6 weeks. The
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Two Attentional Models of Classical Conditioning: Variations in CS Effectiveness Revisited.
1987-04-03
probability is in closer agreement with empirical expectations, tending to lie on a line with slope equal to 1. Experiments in pigeon autoshaping have shown...Gibbon, J., Farrell, L., Locurto, C.M., Duncan, H., & Terrace, H.S. (1980). Partial reinforcement in autoshaping with pigeons. Animal Learning and
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Thermal particle production in two Taub-Nut type spacetimes
International Nuclear Information System (INIS)
Lapedes, A.S.
1976-01-01
The Hartle-Hawking method of deriving black hole radiance has been extended to non-asymptotically flat de Sitter spacetime by Gibbons and Hawking. We extend this work to Taub-Nut spacetime and a related and more physical spacetime constructed from it by Siklos. (orig./BJ) [de
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Ptok, M; Bonenberger, S; Miller, S; Kühn, D; Jungheim, M
2014-07-01
Laryngeal Adductor Reflex Background: A rapid closure of the vocal folds is necessary, whenever foreign materials or food particles penetrate into the larynx. Otherwise a passage of these particles into the trachea or the lower respiratory tract would be imminent. An aspiration could mechanically block the respiratory tract and cause severe dyspnoea or cause aspiration pneumonia. For this systematic review a selective literature research in PubMed and Scopus using the keywords "laryngeal adductor reflex" and "vocal fold closure" has been carried out. Apart from the oesophago-glottal and pharyngo-glottal closure reflexes, the laryngeal adductor reflex (LAR) has been investigated in particular. The LAR qualifies as a reflectory laryngeal adductor mechanism and involves early, presumably di- or oligosynaptic ipsilateral LAR1 as well as late polysynaptic ipsi- and contralateral LAR2 components. In clinical routine diagnostic settings of dysphagia, LAR is only assessed qualitatively and usually triggered by air pulses or tactile stimulation. Dysphagiologists often find that not only the laryngeal sensibility in general is impaired, but especially the protective laryngeal adduction mechanism, which results in a higher risk of aspiration. Thus, it appears mandatory to test the LAR not only qualitatively but also quantitatively. Unfortunately a valid and reliable method that can be employed in clinical practice has not yet been put forward. © Georg Thieme Verlag KG Stuttgart · New York.
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Psikolojik Gerilimin Sudanlı Ortaokul Öğrencilerinin Özsaygısı Üzerine Etkisi
Directory of Open Access Journals (Sweden)
Alradi Jadain El IMAM
2014-08-01
Full Text Available Psikolojik gerilimler ve özsaygı, herkesin hayatının bazı dönemlerinde başa çıkmak zorunda olduğu yaygın konulardır. Bu makalenin amacı, psikolojik gerilimler ile özsaygı arasında bir ilişki varsa bunu keşfetmektir. Bu çalışma 350 Sudanlı ortaokul öğrencisi üzerinde gerçekleştirilmiştir. Katılımcılar, Sudan’ın Gezira eyaletinde bulunan Al. Kamleen bölgesinde yer alan ortaokul öğrencileridir. Katılımcılar, psikolojik gerilim ve özsaygıları ölçülmek maksadıyla incelenmiştir. Katılımcıların psikolojik gerilim ve özsaygılarını ölçmek için Fontana & Rida Abouserie Psikolojik Gerilim Ölçeği ve Rosenberg Özsaygı Ölçeği (RSES; 1965 kullanılmıştır. Deneklerin psikolojik gerilim ve özsaygılarını incelemek için Pearson korelasyon tekniği kullanılmıştır. Negatif önemli bir ilişki belirlenmiştir (r = 0.64-, p
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Cordes, Sara; King, Adam Philip; Gallistel, C R
2007-02-22
Evidence suggests that the online combination of non-verbal magnitudes (durations, numerosities) is central to learning in both human and non-human animals [Gallistel, C.R., 1990. The Organization of Learning. MIT Press, Cambridge, MA]. The molecular basis of these computations, however, is an open question at this point. The current study provides the first direct test of temporal subtraction in a species in which the genetic code is available. In two experiments, mice were run in an adaptation of Gibbon and Church's [Gibbon, J., Church, R.M., 1981. Time left: linear versus logarithmic subjective time. J. Exp. Anal. Behav. 7, 87-107] time left paradigm in order to characterize typical responding in this task. Both experiments suggest that mice engaged in online subtraction of temporal values, although the generalization of a learned response rule to novel stimulus values resulted in slightly less systematic responding. Potential explanations for this pattern of results are discussed.
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78 FR 29387 - Government-Owned Inventions, Available for Licensing
2013-05-20
... Heat Shield Having Edgewise Strips of Ablative Material; NASA Case No.: LAR-18166-1: Reactive... Case No.: LAR-18179-1: Processing Device for High-Speed Execution of an xRISC Computer Program. Sumara...
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Joish, Vijay N; Frech, Feride; Lapuerta, Pablo
2017-12-01
Telotristat ethyl (TE) was recently approved for carcinoid syndrome diarrhea (CSD) in patients not adequately controlled with somatostatin analog long-acting release (SSA LAR) therapy alone. A budget impact model was developed to determine the short-term affordability of reimbursing TE in a US health plan. A budget impact model compared health care costs when CSD is managed per current treatment patterns (SSA LAR, reference drug scenario) versus when TE is incorporated in the treatment algorithm (SSA LAR + TE, new drug scenario). Prevalence of CSD, proportion of patients not adequately controlled on SSA LAR, monthly treatment costs (pharmacy and medical), and treatment efficacy were derived from the literature. In the reference drug scenario, an escalated monthly dose of SSA LAR therapy of 40 mg was assumed to treat patients with CSD not adequately controlled on the labeled dose of SSA LAR. In the new drug scenario, TE was added to the maximum labeled monthly dose of SSA LAR therapy of 30 mg. The incremental budget impact was calculated based on an assumed TE market uptake of 28%, 42%, and 55% during Years 1, 2, and 3, respectively. One-way sensitivity analyses were conducted to test model assumptions. A hypothetical health plan of 1 million members was estimated to have 42 prevalent CSD patients of whom 17 would be inadequately controlled on SSA LAR therapy. The monthly medical cost per patient not adequately controlled on SSA LAR in addition to pharmacotherapy was estimated to be $3946 based on the literature. Based on the observed treatment response in a clinical trial of 20% and 44% for the base case reference and new drug scenarios, total per patient per month costs were estimated to be $7563 and $11,205, respectively. Total annual costs in the new drug scenario were estimated to be $2.3 to $2.5 million during the first 3 years. The overall incremental annual costs were estimated to be $154,000 in Year 1, $231,000 in Year 2, and $302,000 in Year 3. This
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Ayhan, Ali
2018-01-01
Sevgili Meslektaşlarım,2016 yılının 4. sayısında birlikteyiz. Bu sayıdan itibaren dergimizin online hizmetleri içinUlakbim tarafından alt yapısı sağlanan Dergipark sisteminden yararlanacağız. Bundan sonra sizdeğerli yazarlar bu platform üzerinden yazılarınızı yükleyecek ve değerlendireceksiniz.Türk Jinekolojik Onkoloji Derneğinin resmi dergisi olan dergimizin yaşamını sürdürebilmesive daha iyi hizmet vermesi için sizlerin yazılarınızı ve özellikle araştırma tipindeki yazılarınızıbekliyoruz. A...
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Energy Technology Data Exchange (ETDEWEB)
Donovan, E. M.; James, H.; Bonora, M.; Yarnold, J. R.; Evans, P. M. [Joint Department of Physics, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton SM2 5PT (United Kingdom); Physics Department, Ipswich Hospital NHS Foundation Trust, Ipswich IP4 5PD (United Kingdom); Department of Academic Radiotherapy, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton SM2 5PT, United Kingdom and School of Radiotherapy, University of Milan, Milan 20122 (Italy); Department of Academic Radiotherapy, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton SM2 5PT (United Kingdom); Centre for Vision Speech and Signal Processing, University of Surrey, Guildford GU2 7XH (United Kingdom)
2012-10-15
Purpose: To compare organ specific cancer incidence risks for standard and complex external beam radiotherapy (including cone beam CT verification) following breast conservation surgery for early breast cancer.Method: Doses from breast radiotherapy and kilovoltage cone beam CT (CBCT) exposures were obtained from thermoluminescent dosimeter measurements in an anthropomorphic phantom in which the positions of radiosensitive organs were delineated. Five treatment deliveries were investigated: (i) conventional tangential field whole breast radiotherapy (WBRT), (ii) noncoplanar conformal delivery applicable to accelerated partial beast irradiation (APBI), (iii) two-volume simultaneous integrated boost (SIB) treatment, (iv) forward planned three-volume SIB, and (v) inverse-planned three volume SIB. Conformal and intensity modulated radiotherapy methods were used to plan the complex treatments. Techniques spanned the range from simple methods appropriate for patient cohorts with a low cancer recurrence risk to complex plans relevant to cohorts with high recurrence risk. Delineated organs at risk included brain, salivary glands, thyroid, contralateral breast, left and right lung, esophagus, stomach, liver, colon, and bladder. Biological Effects of Ionizing Radiation (BEIR) VII cancer incidence models were applied to the measured mean organ doses to determine lifetime attributable risk (LAR) for ages at exposure from 35 to 80 yr according to radiotherapy techniques, and included dose from the CBCT imaging. Results: All LAR decreased with age at exposure and were lowest for brain, thyroid, liver, and bladder (<0.1%). There was little dependence of LAR on radiotherapy technique for these organs and for colon and stomach. LAR values for the lungs for the three SIB techniques were two to three times those from WBRT and APBI. Uncertainties in the LAR models outweigh any differences in lung LAR between the SIB methods. Constraints in the planning of the SIB methods ensured that
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International Nuclear Information System (INIS)
Donovan, E. M.; James, H.; Bonora, M.; Yarnold, J. R.; Evans, P. M.
2012-01-01
Purpose: To compare organ specific cancer incidence risks for standard and complex external beam radiotherapy (including cone beam CT verification) following breast conservation surgery for early breast cancer.Method: Doses from breast radiotherapy and kilovoltage cone beam CT (CBCT) exposures were obtained from thermoluminescent dosimeter measurements in an anthropomorphic phantom in which the positions of radiosensitive organs were delineated. Five treatment deliveries were investigated: (i) conventional tangential field whole breast radiotherapy (WBRT), (ii) noncoplanar conformal delivery applicable to accelerated partial beast irradiation (APBI), (iii) two-volume simultaneous integrated boost (SIB) treatment, (iv) forward planned three-volume SIB, and (v) inverse-planned three volume SIB. Conformal and intensity modulated radiotherapy methods were used to plan the complex treatments. Techniques spanned the range from simple methods appropriate for patient cohorts with a low cancer recurrence risk to complex plans relevant to cohorts with high recurrence risk. Delineated organs at risk included brain, salivary glands, thyroid, contralateral breast, left and right lung, esophagus, stomach, liver, colon, and bladder. Biological Effects of Ionizing Radiation (BEIR) VII cancer incidence models were applied to the measured mean organ doses to determine lifetime attributable risk (LAR) for ages at exposure from 35 to 80 yr according to radiotherapy techniques, and included dose from the CBCT imaging. Results: All LAR decreased with age at exposure and were lowest for brain, thyroid, liver, and bladder (<0.1%). There was little dependence of LAR on radiotherapy technique for these organs and for colon and stomach. LAR values for the lungs for the three SIB techniques were two to three times those from WBRT and APBI. Uncertainties in the LAR models outweigh any differences in lung LAR between the SIB methods. Constraints in the planning of the SIB methods ensured that
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Sagittal crest formation in great apes and gibbons
Balolia, K. L.; Soligo, C.; Wood, B.
2017-01-01
The frequency of sagittal crest expression and patterns of sagittal crest growth and development have been documented in hominoids, including some extinct hominin taxa, and the more frequent expression of the sagittal crest in males has been traditionally linked with the need for larger-bodied individuals to have enough attachment area for the temporalis muscle. In the present study, we investigate sagittal cresting in a dentally mature sample of four hominoid taxa (Pan troglodytes schweinfur...
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1993-07-01
dimensions topics such as timing (e.g., Gibbon & Allan, from interresponse-time duration (e.g.. Alle- 1984), numerositv (e.g., Gallistel , 1989), and...Behavior, 51, 145-162. Snapper, A. G., & Inglis, G. B. (1985). SKED-li soft- Gallistel , C. R. (1989). Animal cognition: The repre- ware system. Kalamazoo
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Stochastic Simulations of Long-Range Forecasting Models. Volume 3. Technical Appendix
1975-10-31
The World Power Structure and the Inequa - lity of: Nat:ions. London: McGibbon and Kce. JOSHUA, W. (1971) Soviet Penetration into tlie Middle East...IPRT M NYEAR =■ % Non-Agricultural Employment for Period T-(J-l) for Nat’.on I = % Urbanization = ALOGIO (% Non-Agricultural Employment ) = ALOGIO
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Triterpenoidal Saponins: Bioactive Secondary Metabolites from Zygophyllum coccineum
2011-01-22
Merfort, Freiburg, Germany Kurt Schmidt, Graz, Austria Thomas Simmet, Ulm, Germany Hermann Stuppner, Innsbruck, Austria Yang-Chang Wu, Taichung, Taiwan ...hyperinsulinemic effects of some Egyptian herbs used for treatment of diabetes mellitus (Type II) in rats. Egypt J Pharm Sci 1995; 36: 331–341 5 Gibbons S
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Statistical Origin of Black Hole Entropy in Matrix Theory
International Nuclear Information System (INIS)
Lowe, D.A.
1998-01-01
The statistical entropy of black holes in matrix theory is considered. Assuming matrix theory is the discretized light-cone quantization of a theory with eleven-dimensional Lorentz invariance, we map the counting problem onto the original Gibbons-Hawking calculations of the thermodynamic entropy. copyright 1998 The American Physical Society
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Assessing the Utility of the Willingness/Prototype Model in Predicting Help-Seeking Decisions
Hammer, Joseph H.; Vogel, David L.
2013-01-01
Prior research on professional psychological help-seeking behavior has operated on the assumption that the decision to seek help is based on intentional and reasoned processes. However, research on the dual-process prototype/willingness model (PWM; Gerrard, Gibbons, Houlihan, Stock, & Pomery, 2008) suggests health-related decisions may also…
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Albert, Mathieu; Laberge, Suzanne; McGuire, Wendy
2012-01-01
This study empirically addresses the claim made by Gibbons et al ("The new production of knowledge: The dynamics of science and research in contemporary societies." Sage, Thousand Oaks, 1994) that a novel form of quality control (associated with Mode 2 knowledge production) is supplementing the "traditional" peer-review process…
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Critical Needs of African Universities: A Shared African-Japanese ...
African Journals Online (AJOL)
Africa is experiencing an explosion in the number of universities and their student population. Borne out of our experience in academia, and informed by a theoretical model of knowledge production formulated by Gibbons (2002), this paper argues that besides the widely recognized need for better mobilization of resources ...
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En sådan konstellation findes ikke
DEFF Research Database (Denmark)
Bøggild, Jacob
En monografi om Lars von Triers såkaldte "depression trilogy", som omfatter filmene "Antichrist", "Melancholia" og "Nymphomaniac".......En monografi om Lars von Triers såkaldte "depression trilogy", som omfatter filmene "Antichrist", "Melancholia" og "Nymphomaniac"....
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Dialektisk billede af Benjamin
DEFF Research Database (Denmark)
Bøggild, Jacob
2004-01-01
Anmeldelse af Lars Brückner: "Løse blade. Læseren, kritikeren og fortælleren Walter Benjamin"......Anmeldelse af Lars Brückner: "Løse blade. Læseren, kritikeren og fortælleren Walter Benjamin"...
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Stelten, Mark E.; Cooper, Kari M.; Vazquez, Jorge A.; Reid, Mary R.; Barfod, Gry H.; Wimpenny, Josh; Yin, Qing-Zhu
2013-01-01
The nature of compositional heterogeneity within large silicic magma bodies has important implications for how silicic reservoirs are assembled and evolve through time. We examine compositional heterogeneity in the youngest (~170 to 70 ka) post-caldera volcanism at Yellowstone caldera, the Central Plateau Member (CPM) rhyolites, as a case study. We compare 238U–230Th age, trace-element, and Hf isotopic data from zircons, and major-element, Ba, and Pb isotopic data from sanidines hosted in two CPM rhyolites (Hayden Valley and Solfatara Plateau flows) and one extracaldera rhyolite (Gibbon River flow), all of which erupted near the caldera margin ca. 100 ka. The Hayden Valley flow hosts two zircon populations and one sanidine population that are consistent with residence in the CPM reservoir. The Gibbon River flow hosts one zircon population that is compositionally distinct from Hayden Valley flow zircons. The Solfatara Plateau flow contains multiple sanidine populations and all three zircon populations found in the Hayden Valley and Gibbon River flows, demonstrating that the Solfatara Plateau flow formed by mixing extracaldera magma with the margin of the CPM reservoir. This process highlights the dynamic nature of magmatic interactions at the margins of large silicic reservoirs. More generally, Hf isotopic data from the CPM zircons provide the first direct evidence for isotopically juvenile magmas contributing mass to the youngest post-caldera magmatic system and demonstrate that the sources contributing magma to the CPM reservoir were heterogeneous in 176Hf/177Hf at ca. 100 ka. Thus, the limited compositional variability of CPM glasses reflects homogenization occurring within the CPM reservoir, not a homogeneous source.
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OTOMATİK YÖNLENDİRMELİ ARAÇ (OYA SİSTEMLERİ VE DEPO BAKIMINDA ROTALAMA PROBLEMİ
Directory of Open Access Journals (Sweden)
Fatih YİĞİT
2003-02-01
Full Text Available Fabrika otomasyonunun tam otomasyona geçiş aşamasında malzeme taşıma sistemleri oldukça önem taşır. Malzeme taşıma sistemleri arasında en fazla teknolojik gelişmeler otomatik yönlendirmeli araçlar (OYA üzerinde yoğunlaşmıştır. OYA'lar birim yükü dışarıdan gelen rehber sinyaller vasıtasıyla bir yerden başka bir yere taşıyan sürücüsüz araçlardır. Bu araçlar sahip oldukları esneklik özellikleri ile günümüzde hizmet sektöründen üretim sektörüne bir çok alanda kullanılabilmektedir. Bu çalışmada, hava araçlarına ait parçaların (AH-1W model helikopterin bakım, onarım ve yenileştirme işlemlerinin yapıldığı depo bakım atölyelerinde (aviyonik atölyeleri parçaların etkin ve hızlı bir şekilde dağıtılıp toplanması işlemlerinde OYA'ların kullanımı le alınarak OYA tasarımı ve OYA'ların rotalanması problemi incelenmiştir. OYA'ların rotalanması problemi gezgin satıcı problemi ile benzer bir problemdir. Bu problem 0-1 tamsayılı programlama modeli olarak modellenmiş ve LINGO paket programı kullanılarak çözülmüştür.
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Trenti, Loris; Galvez, Ana; Biondo, Sebastiano; Solis, Alejandro; Vallribera-Valls, Francesc; Espin-Basany, Eloy; Garcia-Granero, Alvaro; Kreisler, Esther
2018-04-04
The aim of this study was to analyze the quality of life (QoL), low anterior resection syndrome (LARS) and fecal incontinence after surgery for mid to low rectal cancer and its relationship with the type of surgical procedure performed. A cross-sectional cohort survey study of 358 patients operated on for mid to low rectal cancer. Patients were included in three groups: abdominoperineal resection (APR), low mechanical colorectal anastomosis (CRA) and hand-sewn coloanal anastomosis (CAA). The QLQ-C30/CR29 questionnaires, LARS and Vaizey scores were used to study QoL and defecatory dysfunction. Multivariable analysis was used to estimate the prognostic effect of the variables on QoL and LARS scores. 62.6% of the patients answered the survey. The global QoL score was similar among APR, CRA and CAA. Patients' body image perception was significantly worse after APR than after CRA or CAA. LARS score was better in CRA group (p = 0.002). A major LARS was observed in 83.3% of the patients who underwent CAA and in 56.6% of the patients who underwent CRA. No relationship between surgical procedures and the global QoL score was observed. Neoadjuvant radiotherapy (p = 0.048) and CAA (p = 0.005) were associated with a major LARS. The Vaizey score was higher for CAA than for CRA (p = 0.036). Though CAA group presents worse LARS and higher faecal incontinence scores respect CRA patients, and APR is related with a worse body image, global QoL was similar in the three groups. Copyright © 2018 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
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Directory of Open Access Journals (Sweden)
Lijun Wang
Full Text Available Proanthocyanidins (PAs contribute to poplar defense mechanisms against biotic and abiotic stresses. Transcripts of PA biosynthetic genes accumulated rapidly in response to infection by the fungus Marssonina brunnea f.sp. multigermtubi, treatments of salicylic acid (SA and wounding, resulting in PA accumulation in poplar leaves. Anthocyanidin reductase (ANR and leucoanthocyanidin reductase (LAR are two key enzymes of the PA biosynthesis that produce the main subunits: (+-catechin and (--epicatechin required for formation of PA polymers. In Populus, ANR and LAR are encoded by at least two and three highly related genes, respectively. In this study, we isolated and functionally characterized genes PtrANR1 and PtrLAR1 from P. trichocarpa. Phylogenetic analysis shows that Populus ANR1 and LAR1 occurr in two distinct phylogenetic lineages, but both genes have little difference in their tissue distribution, preferentially expressed in roots. Overexpression of PtrANR1 in poplar resulted in a significant increase in PA levels but no impact on catechin levels. Antisense down-regulation of PtrANR1 showed reduced PA accumulation in transgenic lines, but increased levels of anthocyanin content. Ectopic expression of PtrLAR1 in poplar positively regulated the biosynthesis of PAs, whereas the accumulation of anthocyanin and flavonol was significantly reduced (P<0.05 in all transgenic plants compared to the control plants. These results suggest that both PtrANR1 and PtrLAR1 contribute to PA biosynthesis in Populus.
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Wani, Rauf Ahmad; Bhat, Ikhlaq-Ul-Aziz; Parray, Fazl Qadir; Chowdri, Nisar Ahmad
2017-12-01
Quality of life (QoL) is a key element in rectal cancer (RC) patients. There is not much data regarding this from North India. This study assesses QoL following low anterior resection (LAR) and abdominoperineal resection (APR), operated for low rectal tumors at a high-volume center in northern India. One-hundred-thirty patients of rectal carcinoma were prospectively assessed for quality of life using the European Organization for Cancer QLQ-30 and CR29 questionnaires and compared with reference data population. There was no significant difference in the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 functional or symptom score between the study group and reference data population. Specific functional and symptom QoL scores of the study group were comparable to that of reference data population. There was no significant difference in the EORTC QLQ-C30 functional or symptom score between APR and LAR groups, except for the symptom of nausea and vomiting which was reported significantly more by the LAR group patients than APR group ( p = 0.001). LAR patients had significantly higher scores with regard to nausea and vomiting than patients with an APR ( p Quality of life after APR and LAR for rectal carcinoma was found to be comparable to the reference data population, and the QoL after APR was similar to that after LAR barring a few symptoms.
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In-situ measurement of the light attenuation in liquid argon in the GERDA cryostat
Energy Technology Data Exchange (ETDEWEB)
Schneider, Birgit [IKTP, TU Dresden (Germany); Collaboration: GERDA-Collaboration
2015-07-01
GERDA is an experiment searching for neutrinoless double beta decay in {sup 76}Ge. It uses germanium detectors which are enriched in {sup 76}Ge and operates them naked in liquid argon (LAr), which serves both as a coolant and a shield for external radiation. For phase II of GERDA it is planned to reach an exposure of 100 kg . yr with a BI of 10{sup -3} cts/(kg . yr . keV). One of the major improvements to further reduce the BI is to instrument the LAr to act as an additional background veto. The attenuation of the scintillation light in LAr creates a constraint on the effective active volume of the LAr veto and is therefore a key parameter to characterize the instrumentation. In order to measure the light attenuation in LAr, a setup was designed that could be deployed directly into the GERDA cryostat. This setup contains a movable beta source and a PMT to detect the scintillation light at different distances. The talk will describe in detail the construction of the setup, its successful deployment in the GERDA cryostat and the consecutive analysis of the acquired data.
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Large area liquid argon detectors for interrogation systems
Energy Technology Data Exchange (ETDEWEB)
Gary, Charles; Kane, Steve; Firestone, Murray I.; Smith, Gregory [Adelphi Technology LLC, Purdue Technology Center, 5225 Exploration Drive, Indianapolis, IN 46241 (United States); Gozani, Tsahi; Brown, Craig; Kwong, John; King, Michael J. [Rapiscan Laboratories, 520 Almanor Avenue, Sunnyvale, CA 94085 (United States); Nikkel, James A.; McKinsey, Dan [Physics Department, Yale University, New Haven, CT 06520 (United States)
2013-04-19
Measurements of the efficiency, pulse shape, and energy and time resolution of liquid argon (LAr) detectors are presented. Liquefied noble gas-based (LNbG) detectors have been developed for the detection of dark matter and neutrinoless double-beta decay. However, the same qualities that make LNbG detectors ideal for these applications, namely their size, cost, efficiency, pulse shape discrimination and resolution, make them promising for portal screening and the detection of Special Nuclear Materials (SNM). Two 18-liter prototype detectors were designed, fabricated, and tested, one with pure LAr and the other doped with liquid Xe (LArXe). The LArXe detector presented the better time and energy resolution of 3.3 ns and 20% at 662 KeV, respectively. The total efficiency of the detector was measured to be 35% with 4.5% of the total photons detected in the photopeak.
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Large area liquid argon detectors for interrogation systems
International Nuclear Information System (INIS)
Gary, Charles; Kane, Steve; Firestone, Murray I.; Smith, Gregory; Gozani, Tsahi; Brown, Craig; Kwong, John; King, Michael J.; Nikkel, James A.; McKinsey, Dan
2013-01-01
Measurements of the efficiency, pulse shape, and energy and time resolution of liquid argon (LAr) detectors are presented. Liquefied noble gas-based (LNbG) detectors have been developed for the detection of dark matter and neutrinoless double-beta decay. However, the same qualities that make LNbG detectors ideal for these applications, namely their size, cost, efficiency, pulse shape discrimination and resolution, make them promising for portal screening and the detection of Special Nuclear Materials (SNM). Two 18-liter prototype detectors were designed, fabricated, and tested, one with pure LAr and the other doped with liquid Xe (LArXe). The LArXe detector presented the better time and energy resolution of 3.3 ns and 20% at 662 KeV, respectively. The total efficiency of the detector was measured to be 35% with 4.5% of the total photons detected in the photopeak.
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Toprak Faunası: Sınıflandırılması ve Besin Ağındaki Yeri
Çakır, Meriç; Makineci, Ender
2011-01-01
Özet: Toprak ekolojisi; toprak içerisindeki primer üretim, toprak flora ve faunası, ölüörtü ayrışması, besin döngüsü, toprak besin ağı, toprak biyoçeşitliliği ve bunların toprak süreçleriyle arasındaki ilişkileri araştırmaktadır. Toprak içerisinde yaşayan canlılar bu süreçlerde hayati rol oynarlar, ancak bu canlıların tek başlarına etkilerinin hesaplanması çok zordur. Bu süreçleri çalışan toprak ekologları, canlıları birlik ve fonksiyonel grup olarak iki basit birime ayırmaktadır. Toprak canl...
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Quantum Gravity Effects in Cosmology
Directory of Open Access Journals (Sweden)
Gu Je-An
2018-01-01
Full Text Available Within the geometrodynamic approach to quantum cosmology, we studied the quantum gravity effects in cosmology. The Gibbons-Hawking temperature is corrected by quantum gravity due to spacetime fluctuations and the power spectrum as well as any probe field will experience the effective temperature, a quantum gravity effect.
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Thau, Stefan; Aquino, Karl; Wittek, Rafael; Aquino, 27021
A multisource field study of 103 employees and their supervisors tested an extension of uncertainty management theory (E. A. Lind & K. Van den Bos, 2002; K. Van den Bos & E. A. Lind, 2002). According to this theory, persons high in social comparison orientation (F. X. Gibbons & B. P. Buunk, 1999)
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Tonto, Kadri
2016-01-01
Minimalistliku vormiga eramu KODA. Kontseptsiooni autorid Ülar Mark, Taavi Jakobson, Hannes Tamjärv, Kalev Ramjalg, Marek Strandberg; arhitektid Ülar Mark, Kariina Kristiina Kaufmann, Kadri Tonto, Hannes Praks. Eesti Arhitektide Liidu preemia "Väike 2013-2015" laureaat
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KORFAL, Ahu
2016-01-01
Araştırmanın temel amacı, algılanan ekonomik güçlük ve eşler arasındaki çatışma ile ergen problem davranışları arasındaki bağlantıda ebeveyn-ergen ilişkilerinin aracı rolünü incelemektir. Bu amaç çerçevesinde, anılan ilişkiler kız ve erkek ergenlerde Aile Stres Modeli çerçevesinde sınanmıştır. Araştırmanın örneklemini Ankara kent merkezinde bulunan ilköğretim 6. ve 7. Sınıflar ile ortaöğretim 9. ve 10. Sınıflara devam eden ergenler oluşturmaktadır. Çalışmamıza, 518 (%48.5...
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Venkat, Veena L; Nick, Todd G; Wang, Yu; Bucuvalas, John C
2008-02-01
Non-adherence to a prescribed immunosuppressive regimen increases risk for late allograft rejection (LAR). We implemented a protocol for immunosuppression management which decreased variation in calcineurin inhibitor blood levels in pediatric liver transplant recipients by controlling for confounders such as physician practice variability. We hypothesized that patients with increased variation in tacrolimus blood levels despite implementation of the immunosuppression management protocol were at increased risk for LAR. We conducted a single center retrospective cohort study of 101 pediatric liver transplant recipients who were at least one year post liver transplantation and receiving tacrolimus for immunosuppression. The primary outcome variable was biopsy proven allograft rejection. Primary candidate predictor variables were the standard deviation (SD) of tacrolimus blood levels (a marker of drug level variability), mean tacrolimus blood level, age, and insurance type. SD of tacrolimus blood levels was determined for each patient from a minimum of four outpatient levels during the study period. Unadjusted and adjusted logistic regression models were used to determine the prognostic value of candidate predictors. The median and interquartile range of the SD of tacrolimus blood levels was 1.6 (1.1, 2.1). Eleven episodes of LAR occurred during the study period. Ten of the 11 episodes occurred in patients with tacrolimus blood level SD > 2. Insurance type, mean tacrolimus blood level and SD of tacrolimus blood levels were significantly related to LAR in the unadjusted analyses (ptype, mean and SD of tacrolimus blood levels was significantly associated with LAR (validated C-statistic = 0.88, p = 0.012). The adjusted odds of rejection for a one unit increase in the SD of tacrolimus blood level was 3.49 (95% CI 1.31 to 9.29). Effects of age and insurance status on LAR did not provide independent prognostic value after controlling for SD. Variation in tacrolimus blood
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Directory of Open Access Journals (Sweden)
Ke-Gang Li
2013-03-01
Full Text Available Proanthocyanidins (PAs are fundamental nutritional metabolites in different types of grape products consumed by human beings. Although the biosynthesis of PAs in berry of Vitis vinifera has gained intensive investigations, the understanding of PAs in other Vitis species is limited. In this study, we report PA formation and characterization of gene expression involved in PA biosynthesis in leaves of V. bellula, a wild edible grape species native to south and south-west China. Leaves are collected at five developmental stages defined by sizes ranging from 0.5 to 5 cm in length. Analyses of thin layer chromatography (TLC and high performance liquid chromatography-photodiode array detector (HPLC-PAD show the formation of (+-catechin, (−-epicatechin, (+-gallocatechin and (−-epigallocatechin during the entire development of leaves. Analyses of butanol-HCl boiling cleavage coupled with spectrometry measurement at 550 nm show a temporal trend of extractable PA levels, which is characterized by an increase from 0.5 cm to 1.5 cm long leaves followed by a decrease in late stages. TLC and HPLC-PAD analyses identify cyanidin, delphinidin and pelargonidin produced from the cleavage of PAs in the butanol-HCl boiling, showing that the foliage PAs of V. bellula include three different types of extension units. Four cDNAs, which encode VbANR, VbDFR, VbLAR1 and VbLAR2, respectively, are cloned from young leaves. The expression patterns of VbANR and VbLAR2 but not VbLAR1 and VbDFR follow a similar trend as the accumulation patterns of PAs. Two cDNAs encoding VbMYBPA1 and VbMYB5a, the homologs of which have been demonstrated to regulate the expression of both ANR and LAR in V. vinifera, are also cloned and their expression profiles are similar to those of VbANR and VbLAR2. In contrast, the expression profiles of MYBA1 and 2 homologs involved in anthocyanin biosynthesis are different from those of VbANR and VbLAR2. Our data show that both ANR and LAR branches are
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Poets Teaching Poets: Self and the World.
Orr, Gregory, Ed.; Voigt, Ellen Bryant, Ed.
This anthology collects essays by current and former lecturers at the Warren Wilson College (North Carolina) MFA Program for Writers. Some of the poets whose essays are included are: Joan Aleshire, Marianne Boruch, Carl Dennis, Stephen Dobyns, Reginald Gibbons, Louise Gluck, Allen Grossman, Robert Hass, Tony Hoagland, Heather McHugh, Gregory Orr,…
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The Clock Is Ticking: Library Orientation as Puzzle Room
Reade, Tripp
2017-01-01
Tripp Reade is the school librarian at Cardinal Gibbons High School in Raleigh, North Carolina. This article describes how he redesigned his school's library orientation program after learning about escape rooms and a variant known as puzzle rooms. Puzzle rooms present players with a set of challenges to solve; they require "teamwork,…
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The Application of Layer Theory to Design: The Control Layer
Gibbons, Andrew S.; Langton, Matthew B.
2016-01-01
A theory of design layers proposed by Gibbons ("An Architectural Approach to Instructional Design." Routledge, New York, 2014) asserts that each layer of an instructional design is related to a body of theory closely associated with the concerns of that particular layer. This study focuses on one layer, the control layer, examining…
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status and behavioural ecology of sengis in the boni-dodori
African Journals Online (AJOL)
The people, traditionally hunter gatherers, now subsist mainly on small scale ..... of wildlife for food is also a threat to sengis (FitzGibbon et al., 1995). ... preference and general appearance of the images with a sample set of images .... Bird. Diversity Survey in the Boni–Dodori Forest System, Kenya. Zoological Society of.
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Directory of Open Access Journals (Sweden)
João Aragão Ximenes Filho
2003-10-01
Full Text Available INTRODUÇÃO: Os papilomas de vias respiratórias são tumores benignos, de caráter recorrente e progressivo, induzidos por vírus. Sua etiologia está relacionada com infecções por papilloma virus humano, sendo descritas duas formas clínicas: juvenil e adulta. OBJETIVO: Comparar as duas formas de apresentação, juvenil e adulta, observando se há diferenças epidemiológicas ou clínicas entre elas. DESENHO DO ESTUDO: Coorte histórica. MATERIAL E MÉTODO: Realizou-se estudo dos pacientes atendidos na Clínica Otorrinolaringológica do HC-FMUSP com diagnóstico de papilomatose laríngea entre 1990 e 1999. Cinqüenta e um pacientes foram identificados, mas sete não confirmaram o diagnóstico. Assim, 44 indivíduos foram a base desta revisão, sendo 47,72% da forma juvenil e 52,27% da forma adulta. RESULTADOS: Não houve predomínio entre os sexos (p=0,98. A idade média de início dos sintomas foi de 5,3 anos na forma juvenil e 42,6 anos na forma adulta. A dispnéia foi mais prevalente na forma juvenil (p=0,03. A taxa de recidiva geral foi de 66%, sendo de 76,2% na forma juvenil e 56,5% na forma adulta (p=0,17. A incidência de recidiva precoce (INTRODUCTION: Airway papillomas are benign tumors with high recurrence and induced by virus. Papillomatosis's etiology is related with papilloma human virus infection. Two clinical forms are described: juvenile and adult. OBJECTIVE: The aim of this study was to compare the two clinical forms of the papillomatosis, juvenile and adult, observing if there are epidemiological or clinical differences between them. STUDY DESIGN: historical cohort. MATERIAL AND METHOD: We studied the patients followed in the ENT Department of HC-FMUSP with diagnosis of laryngeal papilomatose between 1990 and 1999. Fifty-one patients were identified, but seven did not confirm the diagnosis. Thus, 44 individuals were the base of this study, being 47,72% of juvenile form and 52,27% of adult form. RESULTS: There was no
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Liu, Yi; Shi, Zi; Maximova, Siela; Payne, Mark J; Guiltinan, Mark J
2013-12-05
The proanthocyanidins (PAs), a subgroup of flavonoids, accumulate to levels of approximately 10% total dry weight of cacao seeds. PAs have been associated with human health benefits and also play important roles in pest and disease defense throughout the plant. To dissect the genetic basis of PA biosynthetic pathway in cacao (Theobroma cacao), we have isolated three genes encoding key PA synthesis enzymes, anthocyanidin synthase (ANS), anthocyanidin reductase (ANR) and leucoanthocyanidin reductase (LAR). We measured the expression levels of TcANR, TcANS and TcLAR and PA content in cacao leaves, flowers, pod exocarp and seeds. In all tissues examined, all three genes were abundantly expressed and well correlated with PA accumulation levels, suggesting their active roles in PA synthesis. Overexpression of TcANR in an Arabidopsis ban mutant complemented the PA deficient phenotype in seeds and resulted in reduced anthocyanidin levels in hypocotyls. Overexpression of TcANS in tobacco resulted in increased content of both anthocyanidins and PAs in flower petals. Overexpression of TcANS in an Arabidopsis ldox mutant complemented its PA deficient phenotype in seeds. Recombinant TcLAR protein converted leucoanthocyanidin to catechin in vitro. Transgenic tobacco overexpressing TcLAR had decreased amounts of anthocyanidins and increased PAs. Overexpressing TcLAR in Arabidopsis ldox mutant also resulted in elevated synthesis of not only catechin but also epicatechin. Our results confirm the in vivo function of cacao ANS and ANR predicted based on sequence homology to previously characterized enzymes from other species. In addition, our results provide a clear functional analysis of a LAR gene in vivo.
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Functional results of robotic total intersphincteric resection with hand-sewn coloanal anastomosis.
Luca, F; Valvo, M; Guerra-Cogorno, M; Simo, D; Blesa-Sierra, E; Biffi, R; Garberoglio, C
2016-06-01
In recent decades there has been an increasing trend toward sphincter-preserving procedures for the treatment of low rectal cancer. Robotic surgery is considered to be particularly beneficial when operating in the deep pelvis, where laparoscopy presents technical limitations. The aim of this study was to prospectively evaluate the functional outcomes in patients affected by rectal cancer after robotic total intersphincteric resection (ISR) with hand-sewn coloanal anastomosis. From March 2008 to October 2012, 23 consecutive patients affected by distal rectal adenocarcinoma underwent robotic ISR. Operative, clinical, pathological and functional data regarding continence or presence of a low anterior resection syndrome (LARS) were prospectively collected in a database. Twenty-three consecutive patients were included in the study: 8 men and 15 women. The mean age was 60.2 years (range 28-73). Eighteen (78.3%) had neoadjuvant radiochemotherapy. Conversion rate was nil. The mean operative time was 296.01 min and the mean postoperative hospital stay was 7.43 ± 1.73 days. According to Kirwan's incontinence score, good fecal continence was shown in 85.7% of patients (Grade 1 and 2) and none required a colostomy (Grade 4). Concerning LARS score, the results were as follows: 57.1% patients had no LARS; 19% minor LARS and 23.8% major LARS. Robotic total ISR for low rectal cancer is an acceptable alternative to traditional procedures. Extensive discussion with the patient about the risk of poor functional outcomes or LARS syndrome is mandatory when considering an ISR for treatment of low rectal cancer. Copyright © 2016 Elsevier Ltd. All rights reserved.
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The Single-Phase ProtoDUNE Technical Design Report
Energy Technology Data Exchange (ETDEWEB)
Abi, B. [Univ. of Padova (Italy); et al.
2017-06-21
ProtoDUNE-SP is the single-phase DUNE Far Detector prototype that is under construction and will be operated at the CERN Neutrino Platform (NP) starting in 2018. ProtoDUNE-SP, a crucial part of the DUNE effort towards the construction of the first DUNE 10-kt fiducial mass far detector module (17 kt total LAr mass), is a significant experiment in its own right. With a total liquid argon (LAr) mass of 0.77 kt, it represents the largest monolithic single-phase LArTPC detector to be built to date. It's technical design is given in this report.
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Vilela, Alejandra; Cariaga, Rodrigo; González-Paleo, Luciana; Ravetta, Damián
2008-01-01
A trade-off between reproduction and survival arises because current reproduction diminishes levels of a limiting resource such that less can be placed in storage organs for the survival of an organism during the unfavorable season. Oenothera is a particularly suited genus for studying those kind of trade-offs because it contains species with different life-history strategies (annual, biennial and perennial). Since allocation to leaves is a major factor associated with changes in life-history, here we tested the hypothesis that Oenothera leaf attributes would affect plant reproductive effort and therefore, root reserves. We selected two groups of taxa differing in their leaf area ratio (low- and high-LAR) and we compared their pattern of resource allocation to growth, reproduction and storage. Path analysis confirmed our hypothesis that LAR is the most important variable in explaining variation in allocation to reproduction or storage. The group with high allocation to leaves assigned resources preferentially to storage while the other group allocated more resources to reproduction, as predicted. A trade-off between reproduction and storage was only confirmed for the high-LAR group. The low-LAR group showed the life-history tactic of annual plants, while the high-LAR group exhibited a strategy generally associated with perenniality.
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International Nuclear Information System (INIS)
Eschner, Wolfgang; Schmidt, Matthias; Dietlein, Markus; Schicha, Harald
2008-01-01
Full text: Purpose: a) To evaluate the impact of the reduced life expectancy of patients (compared to a non-patient group with same age distribution) on their risk of developing cancer from the diagnostic use of radiation. b) To find an approximation to such reduction in risk which depends only on the patient's age, a, and his life expectancy, but is independent of the choice of values for the baseline risk of cancer incidence, m(a), and the enhanced relative risk ERR(a) from radiation exposure. Method: The lifetime attributable risk LAR (of a radiation-induced malignancy to manifest itself) is a function of age at exposure, e, and given by integrating over attained age, a, the product of ERR(a), baseline cancer risk m(a) and the relative probability of surviving to age a, S'(a,e). We define a 'prognosis-based LAR modifier' (PROLARM) as the ratio of risks for non-patient, LAR(a), and patient, LAR p (a), a dimensionless quantity that gives a measure of reduction of LAR due to the patient's prognosis. With the survival of the patient group, S p ' (a,e), and for any choice of fitted function for ERR(a) like those used in BEIR VII report, PROLARM ≥∫d'(a,e) da/∫S p '(a,e) da, i.e. the ratio of the survival integrals gives a lower (thus conservative) estimate of the reduction in risk. Results: The method was applied to n=4285 patients with metastatic breast cancer for whom survival as a function of age at metastasis was known. Figure shows that LAR is decreased significantly for all ages at exposure. At younger ages, this decrease is more pronounced (PROLARM ≥ 20 for e ≤ 65). Example: using ERR values of BEIR VII, the LAR due to 10 mSv effective dose at age a = 50 would drop from 1.2 E-3 for non-patient to 4.3E-5 for a patient, i.e. by a factor (PROLARM) of 29. Using only survival data, that factor is 27 (but no LAR can be computed). In other words: 10 mSv for a patient correspond risk-wise to 0.4 mSv for non-patient. The method can be applied to any pathology
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Directory of Open Access Journals (Sweden)
Osman Göde
2017-03-01
Full Text Available Araştırmanın amacı; bir üniversitede futbol takımında amatör düzeyde futbol oynayan kadınların bedenlerine ilişkin algılarının ve yaptıkları spora ilişkin toplumsal cinsiyet rollerinin incelenmesidir. Araştırmaya 2014–2015 öğretim yılında Denizli Pamukkale Üniversitesi Kadın futbol takımında oynayan 8 sporcu dâhil edilmiştir. Araştırmanın amacına ulaşabilmek için nitel veri toplama yöntemleri kullanılmıştır. Veriler, içerik analizi yöntemi ile analiz edilmiştir. Araştırmaya katılan kadın futbolcuların toplumsal cinsiyet rollerini anlayabilmek için sporculara “toplumun bir kadın olarak futbol oynamanıza yaklaşımı nasıldır?” sorusu sorulmuş ve cevaplar iki tema altında incelenmiştir. (a Erkeklerin cinsiyetçi bakış açısı (b toplumda kadının yeri. Bununla birlikte, araştırmaya katılan kadın futbolcular genel olarak kendi bedenlerinden memnun olduklarını ve dış görünüşleriyle ilgili tercihleri yaparken “rahat olmayı” ön plana koyduklarını belirtmişler ve örnek aldıkları futbolcuların çoğunlukla erkek olduğunu ve bu durumun dış görünüşlerini etkileyebiliyor olabileceğini de ifade etmişlerdir.
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Toric geometry of G2-manifolds
DEFF Research Database (Denmark)
Madsen, Thomas Bruun; Swann, Andrew Francis
We consider G2-manifolds with an effective torus action that is multi-Hamiltonian for one or more of the defining forms. The case of T3-actions is found to be distinguished. For such actions multi-Hamiltonian with respect to both the three- and four-form, we derive a Gibbons-Hawking type ansatz...
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South Asia | Page 112 | IDRC - International Development Research ...
International Development Research Centre (IDRC) Digital Library (Canada)
At the beginning of this century, gibbons could have travelled from China to Singapore by swinging from tree to tree. The past 50 years, however, have seen the forests of Southeast Asia largely disappear. The reasons for this devastation are still poorly understood, but the results are tragically all too visible. Increased soil ...
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Development | Page 20 | IDRC - International Development ...
International Development Research Centre (IDRC) Digital Library (Canada)
At the beginning of this century, gibbons could have travelled from China to Singapore by swinging from tree to tree. The past 50 years, however, have seen the forests of Southeast Asia largely disappear. The reasons for this devastation are still poorly understood, but the results are tragically all too visible. Increased soil ...
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Nevada, the Great Recession, and Education
Verstegen, Deborah A.
2013-01-01
The impact of the Great Recession and its aftermath has been devastating in Nevada, especially for public education. This article discusses the budget shortfalls and the impact of the economic crisis in Nevada using case study methodology. It provides a review of documents, including Governor Gibbon's proposals for the public K-12 education system…