Differences in baseline lung cancer mortality between the German uranium miners cohort and the population of the former German Democratic Republic (1960-2003).

Science.gov (United States)

Walsh, Linda; Dufey, Florian; Möhner, Matthias; Schnelzer, Maria; Tschense, Annemarie; Kreuzer, Michaela

2011-03-01

A previous analysis of the radon-related lung cancer mortality risk, in the German uranium miners cohort, using Poisson modeling techniques, noted internal (spontaneous) rates that were higher on average than the external rates by 16.5% (95% CI: 9%; 24%). The main purpose of the present paper is to investigate the nature of, and possible reasons for, this difference by comparing patterns in spontaneous lung cancer mortality rates in a cohort of male miners involved in uranium extraction at the former Wismut mining company in East Germany with national male rates from the former German Democratic Republic. The analysis is based on miner data for 3,001 lung cancer deaths, 1.76 million person-years for the period 1960-2003, and national rates covering the same calendar-year range. Simple "age-period-cohort" graphical analyses were applied to assess the main qualitative differences between the national and cohort baseline lung cancer rates. Some differences were found to occur mainly at higher attained ages above 70 years. Although many occupational risk factors may have contributed to these observed age differences, only the effects of smoking have been assessed here by applying the Peto-Lopez indirect method for calculating smoking attributability. It is inferred that the observed age differences could be due to the greater prevalence of smoking and more mature smoking epidemic in the Wismut cohort compared to the general population of the former German Democratic Republic. In view of these observed differences between external population-based rates and internal (spontaneous) cohort baseline lung cancer rates, it is strongly recommended to apply only the internal rates in future analyses of uranium miner cohorts. © Springer-Verlag 2010

Long-term energy efficiency analysis requires solid energy statistics: The case of the German basic chemical industry

International Nuclear Information System (INIS)

Saygin, D.; Worrell, E.; Tam, C.; Trudeau, N.; Gielen, D.J.; Weiss, M.; Patel, M.K.

2012-01-01

Analyzing the chemical industry’s energy use is challenging because of the sector’s complexity and the prevailing uncertainty in energy use and production data. We develop an advanced bottom-up model (PIE-Plus) which encompasses the energy use of the 139 most important chemical processes. We apply this model in a case study to analyze the German basic chemical industry’s energy use and energy efficiency improvements in the period between 1995 and 2008. We compare our results with data from the German Energy Balances and with data published by the International Energy Agency (IEA). We find that our model covers 88% of the basic chemical industry’s total final energy use (including non-energy use) as reported in the German Energy Balances. The observed energy efficiency improvements range between 2.2 and 3.5% per year, i.e., they are on the higher side of the values typically reported in literature. Our results point to uncertainties in the basic chemical industry’s final energy use as reported in the energy statistics and the specific energy consumption values. More efforts are required to improve the quality of the national and international energy statistics to make them useable for reliable monitoring of energy efficiency improvements of the chemical industry. -- Highlights: ► An advanced model was developed to estimate German chemical industry’s energy use. ► For the base year (2000), model covers 88% of the sector’s total final energy use. ► Sector’s energy efficiency improved between 2.2 and 3.5%/yr between 1995 and 2008. ► Improved energy statistics are required for accurate monitoring of improvements.

Kidney cancer mortality and ionizing radiation among French and German uranium miners

International Nuclear Information System (INIS)

Drubay, Damien; Ancelet, Sophie; Laurier, Dominique; Rage, Estelle; Acker, Alain; Kreuzer, Michaela

2014-01-01

The investigation of potential adverse health effects of occupational exposures to ionizing radiation, on uranium miners, is an important area of research. Radon is a well-known carcinogen for lung, but the link between radiation exposure and other diseases remains controversial, particularly for kidney cancer. The aims of this study were therefore to perform external kidney cancer mortality analyses and to assess the relationship between occupational radiation exposure and kidney cancer mortality, using competing risks methodology, from two uranium miners cohorts. The French (n = 3,377) and German (n = 58,986) cohorts of uranium miners included 11 and 174 deaths from kidney cancer. For each cohort, the excess of kidney cancer mortality has been assessed by standardized mortality ratio (SMR) corrected for the probability of known causes of death. The associations between cumulative occupational radiation exposures (radon, external gamma radiation and long-lived radionuclides) or kidney equivalent doses and both the cause-specific hazard and the probability of occurrence of kidney cancer death have been estimated with Cox and Fine and Gray models adjusted to date of birth and considering the attained age as the timescale. No significant excess of kidney cancer mortality has been observed neither in the French cohort (SMR = 1.49, 95 % confidence interval [0.73; 2.67]) nor in the German cohort (SMR = 0.91 [0.77; 1.06]). Moreover, no significant association between kidney cancer mortality and any type of occupational radiation exposure or kidney equivalent dose has been observed. Future analyses based on further follow-up updates and/or large pooled cohorts should allow us to confirm or not the absence of association. (orig.)

Kidney cancer mortality and ionizing radiation among French and German uranium miners

Energy Technology Data Exchange (ETDEWEB)

Drubay, Damien; Ancelet, Sophie; Laurier, Dominique; Rage, Estelle [Institut de Radioprotection et de Surete Nucleaire (IRSN), Laboratory of Epidemiology, Fontenay-aux-Roses cedex (France); Acker, Alain [AREVA NC, Paris (France); Kreuzer, Michaela [Federal Office for Radiation Protection and Health, Department of Radiation Protection and Health, Neuherberg (Germany)

2014-08-15

The investigation of potential adverse health effects of occupational exposures to ionizing radiation, on uranium miners, is an important area of research. Radon is a well-known carcinogen for lung, but the link between radiation exposure and other diseases remains controversial, particularly for kidney cancer. The aims of this study were therefore to perform external kidney cancer mortality analyses and to assess the relationship between occupational radiation exposure and kidney cancer mortality, using competing risks methodology, from two uranium miners cohorts. The French (n = 3,377) and German (n = 58,986) cohorts of uranium miners included 11 and 174 deaths from kidney cancer. For each cohort, the excess of kidney cancer mortality has been assessed by standardized mortality ratio (SMR) corrected for the probability of known causes of death. The associations between cumulative occupational radiation exposures (radon, external gamma radiation and long-lived radionuclides) or kidney equivalent doses and both the cause-specific hazard and the probability of occurrence of kidney cancer death have been estimated with Cox and Fine and Gray models adjusted to date of birth and considering the attained age as the timescale. No significant excess of kidney cancer mortality has been observed neither in the French cohort (SMR = 1.49, 95 % confidence interval [0.73; 2.67]) nor in the German cohort (SMR = 0.91 [0.77; 1.06]). Moreover, no significant association between kidney cancer mortality and any type of occupational radiation exposure or kidney equivalent dose has been observed. Future analyses based on further follow-up updates and/or large pooled cohorts should allow us to confirm or not the absence of association. (orig.)

Cosmic radiation and mortality from cancer among male German airline pilots: extended cohort follow-up

International Nuclear Information System (INIS)

Hammer, Gaël Paul; Blettner, Maria; Langner, Ingo; Zeeb, Hajo

2012-01-01

Commercial airline pilots are exposed to cosmic radiation and other specific occupational factors, potentially leading to increased cancer mortality. This was analysed in a cohort of 6,000 German cockpit crew members. A mortality follow-up for the years 1960–2004 was performed and occupational and dosimetry data were collected for this period. 405 deaths, including 127 cancer deaths, occurred in the cohort. The mortality from all causes and all cancers was significantly lower than in the German population. Total mortality decreased with increasing radiation doses (rate ratio (RR) per 10 mSv: 0.85, 95 % CI: 0.79, 0.93), contrasting with a non-significant increase of cancer mortality (RR per 10 mSv: 1.05, 95 % CI: 0.91, 1.20), which was restricted to the group of cancers not categorized as radiogenic in categorical analyses. While the total and cancer mortality of cockpit crew is low, a positive trend of all cancer with radiation dose is observed. Incomplete adjustment for age, other exposures correlated with duration of employment and a healthy worker survivor effect may contribute to this finding. More information is expected from a pooled analysis of updated international aircrew studies.

Risk factors for nasal malignancies in German men: the South-German Nasal cancer study.

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Greiser, Eberhard M; Greiser, Karin Halina; Ahrens, Wolfgang; Hagen, Rudolf; Lazszig, Roland; Maier, Heinz; Schick, Bernhard; Zenner, Hans Peter

2012-11-06

There are few studies of the effects of nasal snuff and environmental factors on the risk of nasal cancer. This study aimed to investigate the impact of using nasal snuff and of other risk factors on the risk of nasal cancer in German men. A population-based case-control study was conducted in the German Federal States of Bavaria and Baden-Württemberg. Tumor registries and ear, nose and throat departments provided access to patients born in 1926 or later. Telephone interviews were conducted with 427 cases (mean age 62.1 years) and 2.401 population-based controls (mean age 60.8 years). Ever-use of nasal snuff was associated with an odds ratio (OR) for nasal cancer of 1.45 (95% confidence interval [CI] 0.88-2.38) in the total study population, whereas OR in smokers was 2.01 (95% CI 1.00-4.02) and in never smokers was 1.10 (95% CI 0.43-2.80). The OR in ever-smokers vs. never-smokers was 1.60 (95% CI 1.24-2.07), with an OR of 1.06 (95% CI 1.05-1.07) per pack-year smoked, and the risk was significantly decreased after quitting smoking. Exposure to hardwood dust for at least 1 year resulted in an OR of 2.33 (95% CI 1.40-3.91) in the total population, which was further increased in never-smokers (OR 4.89, 95% CI 1.92-12.49) in analyses stratified by smoking status. The OR for nasal cancer after exposure to organic solvents for at least 1 year was 1.53 (1.17-2.01). Ever-use of nasal sprays/nasal lavage for at least 1 month rendered an OR of 1.59 (1.04-2.44). The OR after use of insecticides in homes was 1.48 (95% CI 1.04-2.11). Smoking and exposure to hardwood dust were confirmed as risk factors for nasal carcinoma. There is evidence that exposure to organic solvents, and in-house use of insecticides could represent novel risk factors. Exposure to asbestos and use of nasal snuff were risk factors in smokers only.

Diet and Other Lifestyle Factors Associated with Prostate Cancer Differ Between the German and Italian Region of Switzerland.

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Richard, Aline; Faeh, David; Bopp, Matthias; Rohrmann, Sabine

2017-12-08

In Switzerland, prostate cancer mortality is higher in the German than in the Italian-speaking region. We aimed at exploring the association of living in one of the two regions with lifestyle factors presumably lowering the risk of prostate cancer. We pooled data from the Swiss Health Survey, conducted every 5 years 1992 - 2012. Information on diet (meat, fish, dairy, fruits and vegetables), alcohol, smoking, physical activity and body mass index were dichotomized into "risky" and "risk-reducing" lifestyle behaviour with respect to prostate cancer. Multivariable logistic regression analyses were performed to assess associations between the German and Italian region of Switzerland and each single lifestyle factor. Living in the Italian region was associated with "risk-reducing" diet, i.e. with a higher prevalence of low dairy products and meat consumption and high fish consumption (odds ratio [OR] 1.34, 95% confidence interval [CI] 1.21 - 1.48; OR 3.31, 95% CI 2.94 - 3.72; OR 1.90, 95% CI 1.71 - 2.12, respectively). However, men in the Italian region were less likely to have low alcohol consumption and regular physical activity than men in the German region (OR 0.43, 95% CI 0.36 - 0.52 and OR 0.77, 95% CI 0.69 - 0.86, respectively). Prostate cancer risk-reducing dietary behaviour (i.e., less dairy products, less meat and more fish) was more common in the Italian region, whereas other risk-reducing lifestyle behaviours were more common in the German region.

Radon and risk of death from cancer and cardiovascular diseases in the German uranium miners cohort study. Follow-up 1946-2003

International Nuclear Information System (INIS)

Kreuzer, Michaela; Grosche, B.; Schnelzer, M.; Tschense, A.; Dufey, F.; Walsh, L.

2010-01-01

Data from the German uranium miners cohort study were analyzed to investigate the radon-related risk of mortality from cancer and cardiovascular diseases. The Wismut cohort includes 58,987 men who were employed for at least 6 months from 1946 to 1989 at the former Wismut uranium mining company in Eastern Germany. By the end of 2003, a total of 3,016 lung cancer deaths, 3,355 deaths from extrapulmonary cancers, 5,141 deaths from heart diseases and 1,742 deaths from cerebrovascular diseases were observed. Although a number of studies have already been published on various endpoints in the Wismut cohort, the aim of the present analyses is to provide a direct comparison of the magnitude of radon-related risk for different cancer sites and cardiovascular diseases using the same data set, the same follow-up period and the same statistical methods. A specific focus on a group of cancers of the extrathoracic airways is also made here, due to the assumed high organ doses from absorbed radon progeny. Internal Poisson regression was used to estimate the excess relative risk (ERR) per unit of cumulative exposure to radon in working level months (WLM) and its 95% confidence limits (CI). There was a statistically significant increase in the risk of lung cancer with increasing radon exposure (ERR/WLM = 0.19%; 95% CI: 0.17%; 0.22%). A smaller, but also statistically significant excess was found for cancers of the extrathoracic airways and trachea (ERR/WLM = 0.062%; 95% CI: 0.002%; 0.121%). Most of the remaining nonrespiratory cancer sites showed a positive relationship with increasing radon exposure, which, however, did not reach statistical significance. No increase in risk was noted for coronary heart diseases (ERR/WLM = 0.0003%) and cerebrovascular diseases (ERR/WLM = 0.001%). The present data provide clear evidence of an increased radon-related risk of death from lung cancer, some evidence for an increased radon-related risk of death from cancers of the extrathoracic airways

Radon and risk of death from cancer and cardiovascular diseases in the German uranium miners cohort study: follow-up 1946-2003.

Science.gov (United States)

Kreuzer, Michaela; Grosche, B; Schnelzer, M; Tschense, A; Dufey, F; Walsh, L

2010-05-01

Data from the German uranium miners cohort study were analyzed to investigate the radon-related risk of mortality from cancer and cardiovascular diseases. The Wismut cohort includes 58,987 men who were employed for at least 6 months from 1946 to 1989 at the former Wismut uranium mining company in Eastern Germany. By the end of 2003, a total of 3,016 lung cancer deaths, 3,355 deaths from extrapulmonary cancers, 5,141 deaths from heart diseases and 1,742 deaths from cerebrovascular diseases were observed. Although a number of studies have already been published on various endpoints in the Wismut cohort, the aim of the present analyses is to provide a direct comparison of the magnitude of radon-related risk for different cancer sites and cardiovascular diseases using the same data set, the same follow-up period and the same statistical methods. A specific focus on a group of cancers of the extrathoracic airways is also made here, due to the assumed high organ doses from absorbed radon progeny. Internal Poisson regression was used to estimate the excess relative risk (ERR) per unit of cumulative exposure to radon in working level months (WLM) and its 95% confidence limits (CI). There was a statistically significant increase in the risk of lung cancer with increasing radon exposure (ERR/WLM = 0.19%; 95% CI: 0.17%; 0.22%). A smaller, but also statistically significant excess was found for cancers of the extrathoracic airways and trachea (ERR/WLM = 0.062%; 95% CI: 0.002%; 0.121%). Most of the remaining nonrespiratory cancer sites showed a positive relationship with increasing radon exposure, which, however, did not reach statistical significance. No increase in risk was noted for coronary heart diseases (ERR/WLM = 0.0003%) and cerebrovascular diseases (ERR/WLM = 0.001%). The present data provide clear evidence of an increased radon-related risk of death from lung cancer, some evidence for an increased radon-related risk of death from cancers of the extrathoracic airways

Statistical Tutorial | Center for Cancer Research

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Recent advances in cancer biology have resulted in the need for increased statistical analysis of research data.  ST is designed as a follow up to Statistical Analysis of Research Data (SARD) held in April 2018.  The tutorial will apply the general principles of statistical analysis of research data including descriptive statistics, z- and t-tests of means and mean

German Bowel Cancer Center: An Attempt to Improve Treatment Quality

Directory of Open Access Journals (Sweden)

Olof Jannasch

2015-01-01

Full Text Available Background. Colorectal cancer remains the second most common cause of death from malignancies, but treatment results show high diversity. Certified bowel cancer centres (BCC are the basis of a German project for improvement of treatment. The aim of this study was to analyze if certification would enhance short-term outcome in rectal cancer surgery. Material and Methods. This quality assurance study included 8197 patients with rectal cancer treated between 1 January 2008 and 31 December 2010. We compared cohorts treated in certified and noncertified hospitals regarding preoperative variables and perioperative outcomes. Outcomes were verified by matched-pair analysis. Results. Patients of noncertified hospitals had higher ASA-scores, higher prevalence of risk factors, more distant metastases, lower tumour localization, lower frequency of pelvic MRI, and higher frequencies of missing values and undetermined TNM classifications (significant differences only. Outcome analysis revealed more general complications in certified hospitals (20.3% versus 17.4%, p=0.03. Both cohorts did not differ significantly in percentage of R0-resections, intraoperative complications, anastomotic leakage, in-hospital death, and abdominal wall dehiscence. Conclusions. The concept of BCC is a step towards improving the structural and procedural quality. This is a good basis for improving outcome quality but cannot replace it. For a primary surgical disease like rectal cancer a specific, surgery-targeted program is still needed.

Internet Information for Patients on Cancer Diets - an Analysis of German Websites.

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Herth, Natalie; Kuenzel, Ulrike; Liebl, Patrick; Keinki, Christian; Zell, Joerg; Huebner, Jutta

2016-01-01

In recent years, the Internet has become an important source of information for cancer patients. Various cancer diets that are publicized on the Web promise significant benefits. The aim of our study was to evaluate the quality of online patient information about cancer diets. A patient's search for 'cancer diets' on German websites was simulated using the search engine Google. The websites were evaluated utilizing a standardized instrument with formal and content aspects. An analysis of 60 websites revealed that websites from nonprofit associations as well as self-help groups offer the best content and formal ranking. Websites whose owners aim to make a profit, practices that offer cancer diet therapies, and newspapers received the poorest quality score. The majority of content provided on the Web gets published by profit-oriented content groups. The divergence between profit-driven websites offering low-quality content and the few trustworthy websites on cancer diets is enormous. The information given online about cancer diets may turn out to be a hazardous pitfall. In order to present evidence-based information about cancer diets, online information should be replenished to create a more accurate picture and give higher visibility to the right information. © 2016 S. Karger GmbH, Freiburg.

[Continuity of hospital identifiers in hospital discharge data - Analysis of the nationwide German DRG Statistics from 2005 to 2013].

Science.gov (United States)

Nimptsch, Ulrike; Wengler, Annelene; Mansky, Thomas

2016-11-01

In Germany, nationwide hospital discharge data (DRG statistics provided by the research data centers of the Federal Statistical Office and the Statistical Offices of the 'Länder') are increasingly used as data source for health services research. Within this data hospitals can be separated via their hospital identifier ([Institutionskennzeichen] IK). However, this hospital identifier primarily designates the invoicing unit and is not necessarily equivalent to one hospital location. Aiming to investigate direction and extent of possible bias in hospital-level analyses this study examines the continuity of the hospital identifier within a cross-sectional and longitudinal approach and compares the results to official hospital census statistics. Within the DRG statistics from 2005 to 2013 the annual number of hospitals as classified by hospital identifiers was counted for each year of observation. The annual number of hospitals derived from DRG statistics was compared to the number of hospitals in the official census statistics 'Grunddaten der Krankenhäuser'. Subsequently, the temporal continuity of hospital identifiers in the DRG statistics was analyzed within cohorts of hospitals. Until 2013, the annual number of hospital identifiers in the DRG statistics fell by 175 (from 1,725 to 1,550). This decline affected only providers with small or medium case volume. The number of hospitals identified in the DRG statistics was lower than the number given in the census statistics (e.g., in 2013 1,550 IK vs. 1,668 hospitals in the census statistics). The longitudinal analyses revealed that the majority of hospital identifiers persisted in the years of observation, while one fifth of hospital identifiers changed. In cross-sectional studies of German hospital discharge data the separation of hospitals via the hospital identifier might lead to underestimating the number of hospitals and consequential overestimation of caseload per hospital. Discontinuities of hospital

Childhood cancer in the surroundings of German nuclear power plants: report of an ongoing epidemiological study

International Nuclear Information System (INIS)

Schulze-Rath, R.; Kaatsch, P.; Schmiedel, S.; Spix, C.; Blettner, M.

2006-01-01

Epidemiological studies could not show an association between ionising radiation of nuclear power stations in routine operation and the incidence of childhood cancer, yet. The following report presents a case control study conducted by the German Childhood Cancer Registry since autumn 2003. All children in the study region, who were diagnosed with cancer between 1980 and 2003 at an age below five are included. In the first part of the study we investigate whether children with cancer (cases) lived closer to the respective nuclear power stations compared to random children without cancer (controls). In the second part, for a subgroup of cases and controls we conduct computer assisted telephone interviews regarding confounders possibly associated with the exposure of ionising radiation and childhood cancer. Results are expected by the end of 2006. (orig.)

German second-opinion network for testicular cancer: sealing the leaky pipe between evidence and clinical practice.

Science.gov (United States)

Zengerling, Friedemann; Hartmann, Michael; Heidenreich, Axel; Krege, Susanne; Albers, Peter; Karl, Alexander; Weissbach, Lothar; Wagner, Walter; Bedke, Jens; Retz, Margitta; Schmelz, Hans U; Kliesch, Sabine; Kuczyk, Markus; Winter, Eva; Pottek, Tobias; Dieckmann, Klaus-Peter; Schrader, Andres Jan; Schrader, Mark

2014-06-01

In 2006, the German Testicular Cancer Study Group initiated an extensive evidence-based national second-opinion network to improve the care of testicular cancer patients. The primary aims were to reflect the current state of testicular cancer treatment in Germany and to analyze the project's effect on the quality of care delivered to testicular cancer patients. A freely available internet-based platform was developed for the exchange of data between the urologists seeking advice and the 31 second-opinion givers. After providing all data relevant to the primary treatment decision, urologists received a second opinion on their therapy plan within testicular cancer patient in Germany were submitted to second-opinion centers. Second-opinion centers can help to improve the implementation of evidence into clinical practice.

The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study.

Science.gov (United States)

Zaineddin, Aida Karina; Buck, Katharina; Vrieling, Alina; Heinz, Judith; Flesch-Janys, Dieter; Linseisen, Jakob; Chang-Claude, Jenny

2012-01-01

Phytoestrogens are structurally similar to estrogens and may affect breast cancer risk by mimicking estrogenic/antiestrogenic properties. In Western societies, whole grains and possibly soy foods are rich sources of phytoestrogens. A population-based case-control study in German postmenopausal women was used to evaluate the association of phytoestrogen-rich foods and dietary lignans with breast cancer risk. Dietary data were collected from 2,884 cases and 5,509 controls using a validated food-frequency questionnaire, which included additional questions phytoestrogen-rich foods. Associations were assessed using conditional logistic regression. All analyses were adjusted for relevant risk and confounding factors. Polytomous logistic regression analysis was performed to evaluate the associations by estrogen receptor (ER) status. High and low consumption of soybeans as well as of sunflower and pumpkin seeds were associated with significantly reduced breast cancer risk compared to no consumption (OR = 0.83, 95% CI = 0.70-0.97; and OR = 0.66, 95% CI = 0.77-0.97, respectively). The observed associations were not differential by ER status. No statistically significant associations were found for dietary intake of plant lignans, fiber, or the calculated enterolignans. Our results provide evidence for a reduced postmenopausal breast cancer risk associated with increased consumption of sunflower and pumpkin seeds and soybeans.

Cancer Patients and the Internet: a Survey Among German Cancer Patients.

Science.gov (United States)

Ebel, Marie-Desiree; Stellamanns, Jan; Keinki, Christian; Rudolph, Ivonne; Huebner, Jutta

2017-09-01

An increasing number of patients and relatives use the Internet to get additional or initial information about their disease. The aim of the study was to reevaluate the Internet usage among German cancer patients. Using a standardized questionnaire, we did an anonymous survey on patients attending a series of lectures on complementary medicine in 2014. We received 255 questionnaires. Nearly 80 % of the participants stated that they used the Internet to read up information about health or medicine issues. There was no significant difference regarding gender, age, or status (patient, current treatment/former treatment; relatives). Most users use the Internet in order to get additional information after a consultation with a physician (82.2 %). Important qualities from the view of the patient are a trustable source (65.3 %), information from experts (59.6 %), and actual information (52.8 %). There is an increasing number of patients in Germany looking for information in the Internet mostly in the intention of getting additional information. Yet, as the quality of information is heterogeneous, false information may lead to distrust in the doctor or wrong decision-making. Accordingly, organizations working on improving quality of cancer care should engage in conveying comprehensive and actual information adapted to the needs of patients. Physicians should know trustful websites for referral of patients.

Breast cancer statistics, 2011.

Science.gov (United States)

DeSantis, Carol; Siegel, Rebecca; Bandi, Priti; Jemal, Ahmedin

2011-01-01

In this article, the American Cancer Society provides an overview of female breast cancer statistics in the United States, including trends in incidence, mortality, survival, and screening. Approximately 230,480 new cases of invasive breast cancer and 39,520 breast cancer deaths are expected to occur among US women in 2011. Breast cancer incidence rates were stable among all racial/ethnic groups from 2004 to 2008. Breast cancer death rates have been declining since the early 1990s for all women except American Indians/Alaska Natives, among whom rates have remained stable. Disparities in breast cancer death rates are evident by state, socioeconomic status, and race/ethnicity. While significant declines in mortality rates were observed for 36 states and the District of Columbia over the past 10 years, rates for 14 states remained level. Analyses by county-level poverty rates showed that the decrease in mortality rates began later and was slower among women residing in poor areas. As a result, the highest breast cancer death rates shifted from the affluent areas to the poor areas in the early 1990s. Screening rates continue to be lower in poor women compared with non-poor women, despite much progress in increasing mammography utilization. In 2008, 51.4% of poor women had undergone a screening mammogram in the past 2 years compared with 72.8% of non-poor women. Encouraging patients aged 40 years and older to have annual mammography and a clinical breast examination is the single most important step that clinicians can take to reduce suffering and death from breast cancer. Clinicians should also ensure that patients at high risk of breast cancer are identified and offered appropriate screening and follow-up. Continued progress in the control of breast cancer will require sustained and increased efforts to provide high-quality screening, diagnosis, and treatment to all segments of the population. Copyright © 2011 American Cancer Society, Inc.

Radiotherapy and subsequent thyroid cancer in German childhood cancer survivors: a nested case–control study

International Nuclear Information System (INIS)

Finke, Isabelle; Scholz-Kreisel, Peter; Hennewig, Ulrike; Blettner, Maria; Spix, Claudia

2015-01-01

Radiotherapy is associated with a risk of subsequent neoplasms (SN) in childhood cancer survivors. It has been shown that children’s thyroid glands are especially susceptible. The aim is to quantify the risk of a second neck neoplasm after primary cancer radiotherapy with emphasis on thyroid cancer. We performed a nested case–control study: 29 individuals, diagnosed with a solid SN in the neck region, including 17 with thyroid cancer, in 1980–2002 and 57 matched controls with single neoplasms were selected from the database of the German Childhood Cancer Registry. We investigated the risk associated with radiotherapy exposure given per body region, adjusted for chemotherapy. 16/17 (94.1 %) thyroid SN cases, 9/12 (75 %) other neck SN cases and 34/57 (59.6 %) controls received radiotherapy, with median doses of 27.8, 25 and 24 Gy, respectively. Radiotherapy exposure to the neck region increased the risk of the other neck SNs by 4.2 % (OR = 1.042/Gy (95 %-CI 0.980-1.109)) and of thyroid SN by 5.1 % (OR = 1.051/Gy (95 %-CI 0.984-1.123)), and radiotherapy to the neck or spine region increased the thyroid risk by 6.6 % (OR = 1.066/Gy (95 %-CI 1.010-1.125)). Chemotherapy was not a confounder. Exposure to other body regions was not associated with increased risk. Radiotherapy in the neck or spine region increases the risk of thyroid cancer, while neck exposure increases the risk of any other solid SN to a similar extent. Other studies showed a decreasing risk of subsequent thyroid cancer for very high doses; we cannot confirm this

Is the prognosis for Japanese and German patients with gastric cancer really different?

Science.gov (United States)

Bollschweiler, E; Boettcher, K; Hoelscher, A H; Sasako, M; Kinoshita, T; Maruyama, K; Siewert, J R

1993-05-15

Differing survival rates have been reported between patients having undergone surgical intervention for the treatment of gastric carcinoma in Japan and Western industrialized countries. Through the actual availability of the data compiled at a major Japanese medical center (National Cancer Center, Tokyo), it was possible, for the first time, to compare the patients and therapeutic results of a Japanese center (n = 1475) with that of a German center (Department of Surgery, Technical University of Munich, Munich; n = 453). The prognostic factors involving both groups were compared. Survival rates were analyzed in univariate and multivariate fashions. Some of the examined prognostic factors, such as sex, histologic type, tumor size, and Borrmann classification, were similarly distributed. Differences in frequency were discovered concerning pathologic tumor (pT), node (pN), and metastasis (pM) categories, localization, and age groups. Univariate analysis showed a 2-year survival rate of 88% for all Japanese patients with gastric cancer compared with 58% for German patients. The 5-year survival rates were 77% and 44%, respectively. The difference in the 2-year and 5-year survival rates for both departments may be related to differences in frequencies of several characteristics. In performing the same analysis in a multivariate fashion for the patient populations at both centers, it became clear that an important prognostic factor was the center itself. The survival curves of patients from Tokyo and Munich with the same prognostic factors demonstrate this difference. These differences, however, were small in comparison with those of univariate analysis. Using a similar classification of the tumor stage and similar prognostic characteristics, the prognosis for gastric cancer in Japan and Germany may be the same.

Suggestions for an adequate risk communication - experiences based on German epidemiological studies on childhood cancer and neighbourhood to nuclear power plants

International Nuclear Information System (INIS)

Kaatsch, P.

2006-01-01

From the example of the German studies on childhood cancer in the vicinity of nuclear power plants general principles for adequate risk communication could be derived. It is particularly important to explain the complexity of the issue to the public in an adequate way, when dealing with topics of such an emotionally loaded nature. Some rules are required, when explaining the nature of risk to the layman, the press, politicians, or scientists from other fields. The main principle is to create a basis of trustfulness, whereupon results can be presented. In this contribution we derive general and proven specific recommendations for adequate risk communication on the basis of experiences made at the German Childhood Cancer Registry. (orig.)

[Validation of the German version of Eating Assessment Tool for head and neck cancer patients].

Science.gov (United States)

Zaretsky, Eugen; Steinbach-Hundt, Silke; Pluschinski, Petra; Grethel, Isabel

2018-04-10

The assessment of subjective swallowing complaints constitutes an important element in a multidimensional, modern management of head and neck cancer patients suffering from dysphagia. For this purpose, an internationally recognized and validated 10-item questionnaire EAT-10 is used that was developed and validated by Belafski et al. in 2008. The purpose of the present study is the translation of EAT-10 into the German language and its validation for head and neck cancer patients. After the translation of EAT-10 into German according to the guidelines for the translation of foreign measuring instruments, a validation of gEAT-10 was carried out on the basis of the sample of 210 head and neck cancer patients. The reliability was determined by means of the internal consistency (Cronbach's Alpha) and item-total correlations (Spearman). The construct validity was verified by the uni- and multivariate analyses of the distribution of gEAT-10 total scores depending on gender, age, BMI, tumor stage and localization as well as type of the oncological therapy. The internal consistency amounted to α = .94, the item-total correlations varied between ρ = .59 and ρ = .85. No significant associations between gEAT-10 total scores and gender as well as age were identified in univariate calculations. Such associations were found for BMI, tumor stage and localization as well as type of the oncological therapy. However, only the tumor stage yielded a significant result in a regression. The gEAT-10 was shown to be a reliable and construct valid questionnaire for the assessment of subjective swallowing complaints in patients with head and neck cancer. © Georg Thieme Verlag KG Stuttgart · New York.

Crunching Numbers: What Cancer Screening Statistics Really Tell Us

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Cancer screening studies have shown that more screening does not necessarily translate into fewer cancer deaths. This article explains how to interpret the statistics used to describe the results of screening studies.

Cancer statistics for African Americans, 2013.

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DeSantis, Carol; Naishadham, Deepa; Jemal, Ahmedin

2013-05-01

In this article, the American Cancer Society estimates the number of new cancer cases and deaths for African Americans and compiles the most recent data on cancer incidence, mortality, survival, and screening prevalence based upon incidence data from the National Cancer Institute, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from the National Center for Health Statistics. It is estimated that 176,620 new cases of cancer and 64,880 deaths will occur among African Americans in 2013. From 2000 to 2009, the overall cancer death rate among males declined faster among African Americans than whites (2.4% vs 1.7% per year), but among females, the rate of decline was similar (1.5% vs 1.4% per year, respectively). The decrease in cancer death rates among African American males was the largest of any racial or ethnic group. The reduction in overall cancer death rates since 1990 in men and 1991 in women translates to the avoidance of nearly 200,000 deaths from cancer among African Americans. Five-year relative survival is lower for African Americans than whites for most cancers at each stage of diagnosis. The extent to which these disparities reflect unequal access to health care versus other factors remains an active area of research. Overall, progress in reducing cancer death rates has been made, although more can and should be done to accelerate this progress through ensuring equitable access to cancer prevention, early detection, and state-of-the-art treatments. Copyright © 2013 American Cancer Society, Inc.

What Do Germans Want to Know About Skin Cancer? A Nationwide Google Search Analysis From 2013 to 2017.

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Seidl, Stefanie; Schuster, Barbara; Rüth, Melvin; Biedermann, Tilo; Zink, Alexander

2018-05-02

Experts worldwide agree that skin cancer is a global health issue, but only a few studies have reported on world populations' interest in skin cancer. Internet search data can reflect the interest of a population in different topics and thereby identify what the population wants to know. Our aim was to assess the interest of the German population in nonmelanoma skin cancer and melanoma. Google AdWords Keyword Planner was used to identify search terms related to nonmelanoma skin cancer and melanoma in Germany from November 2013 to October 2017. The identified search terms were assessed descriptively using SPSS version 24.0. In addition, the search terms were qualitatively categorized. A total of 646 skin cancer-related search terms were identified with 19,849,230 Google searches in the period under review. The search terms with the highest search volume were "skin cancer" (n=2,388,500, 12.03%), "white skin cancer" (n=2,056,900, 10.36%), "basalioma" (n=907,000, 4.57%), and "melanoma" (n=717,800, 3.62%). The most searched localizations of nonmelanoma skin cancer were "nose" (n=93,370, 38.99%) and "face" (n=53,270, 22.24%), and the most searched of melanoma were "nails" (n=46,270, 70.61%) and "eye" (n=10,480, 15.99%). The skin cancer‒related category with the highest search volume was "forms of skin cancer" (n=10,162,540, 23.28%) followed by "skin alterations" (n=4,962,020, 11.36%). Our study provides insight into terms and fields of interest related to skin cancer relevant to the German population. Furthermore, temporal trends and courses are shown. This information could aid in the development and implementation of effective and sustainable awareness campaigns by developing information sources targeted to the population's broad interest or by implementing new Internet campaigns. ©Stefanie Seidl, Barbara Schuster, Melvin Rüth, Tilo Biedermann, Alexander Zink. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 02.05.2018.

[Assessment of Couples' Communication in Patients with Advanced Cancer: Validation of a German Version of the Couple Communication Scale (CCS)].

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Conrad, Martina; Engelmann, Dorit; Friedrich, Michael; Scheffold, Katharina; Philipp, Rebecca; Schulz-Kindermann, Frank; Härter, Martin; Mehnert, Anja; Koranyi, Susan

2018-04-13

There are only a few valid instruments measuring couples' communication in patients with cancer for German speaking countries. The Couple Communication Scale (CCS) represents an established instrument to assess couples' communication. However, there is no evidence regarding the psychometric properties of the German version of the CCS until now and the assumed one factor structure of the CCS was not verified for patients with advanced cancer yet. The CCS was validated as a part of the study "Managing cancer and living meaningfully" (CALM) on N=136 patients with advanced cancer (≥18 years, UICC-state III/IV). The psychometric properties of the scale were calculated (factor reliability, item reliability, average variance extracted [DEV]) and a confirmatory factor analysis was conducted (Maximum Likelihood Estimation). The concurrent validity was tested against symptoms of anxiety (GAD-7), depression (BDI-II) and attachment insecurity (ECR-M16). In the confirmatory factor analysis, the one factor structure showed a low, but acceptable model fit and explained on average 49% of every item's variance (DEV). The CCS has an excellent internal consistency (Cronbachs α=0,91) and was negatively associated with attachment insecurity (ECR-M16: anxiety: r=- 0,55, pCCS is a reliable and valid instrument measuring couples' communication in patients with advanced cancer. © Georg Thieme Verlag KG Stuttgart · New York.

The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study

NARCIS (Netherlands)

Zaineddin, A.K.; Buck, K.; Vrieling, A.; Heinz, J.; Flesch-Janys, D.; Linseisen, J.; Chang-Claude, J.

2012-01-01

Phytoestrogens are structurally similar to estrogens and may affect breast cancer risk by mimicking estrogenic/antiestrogenic properties. In Western societies, whole grains and possibly soy foods are rich sources of phytoestrogens. A population-based case-control study in German postmenopausal women

New Statistical Methodology for Determining Cancer Clusters

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The development of an innovative statistical technique that shows that women living in a broad stretch of the metropolitan northeastern United States, which includes Long Island, are slightly more likely to die from breast cancer than women in other parts of the Northeast.

Statistical Analysis of Research Data | Center for Cancer Research

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Recent advances in cancer biology have resulted in the need for increased statistical analysis of research data. The Statistical Analysis of Research Data (SARD) course will be held on April 5-6, 2018 from 9 a.m.-5 p.m. at the National Institutes of Health's Natcher Conference Center, Balcony C on the Bethesda Campus. SARD is designed to provide an overview on the general principles of statistical analysis of research data.  The first day will feature univariate data analysis, including descriptive statistics, probability distributions, one- and two-sample inferential statistics.

Statistical method on nonrandom clustering with application to somatic mutations in cancer

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Rejto Paul A

2010-01-01

Full Text Available Abstract Background Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a consequence of genomic instability and high levels of proliferation, many passenger mutations that do not contribute to the cancer phenotype arise alongside mutations that drive oncogenesis. While several approaches have been developed to separate driver mutations from passengers, few approaches can specifically identify activating driver mutations in oncogenes, which are more amenable for pharmacological intervention. Results We propose a new statistical method for detecting activating mutations in cancer by identifying nonrandom clusters of amino acid mutations in protein sequences. A probability model is derived using order statistics assuming that the location of amino acid mutations on a protein follows a uniform distribution. Our statistical measure is the differences between pair-wise order statistics, which is equivalent to the size of an amino acid mutation cluster, and the probabilities are derived from exact and approximate distributions of the statistical measure. Using data in the Catalog of Somatic Mutations in Cancer (COSMIC database, we have demonstrated that our method detects well-known clusters of activating mutations in KRAS, BRAF, PI3K, and β-catenin. The method can also identify new cancer targets as well as gain-of-function mutations in tumor suppressors. Conclusions Our proposed method is useful to discover activating driver mutations in cancer by identifying nonrandom clusters of somatic amino acid mutations in protein sequences.

Health-related quality of life of prostate cancer patients compared to the general German population: age-specific results.

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Zenger, Markus; Hinz, Andreas; Stolzenburg, Jens-Uwe; Rabenalt, Robert; Schwalenberg, Thilo; Schwarz, Reinhold

2009-01-01

The objective of this study was to examine the age-specific health-related quality of life (HRQOL) of prostate cancer patients (PCPs). 387 PCPs were asked to self-assess their HRQOL with the EORTC QLQ-C30 questionnaire. Patients' data were compared with those of the general German population. The reported global health/QOL scores of the study group and the general German population are nearly equal. However, most of the subdomains of HRQOL are negatively affected in PCPs, especially in younger patients (

Breast cancer statistics and prediction methodology: a systematic review and analysis.

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Dubey, Ashutosh Kumar; Gupta, Umesh; Jain, Sonal

2015-01-01

Breast cancer is a menacing cancer, primarily affecting women. Continuous research is going on for detecting breast cancer in the early stage as the possibility of cure in early stages is bright. There are two main objectives of this current study, first establish statistics for breast cancer and second to find methodologies which can be helpful in the early stage detection of the breast cancer based on previous studies. The breast cancer statistics for incidence and mortality of the UK, US, India and Egypt were considered for this study. The finding of this study proved that the overall mortality rates of the UK and US have been improved because of awareness, improved medical technology and screening, but in case of India and Egypt the condition is less positive because of lack of awareness. The methodological findings of this study suggest a combined framework based on data mining and evolutionary algorithms. It provides a strong bridge in improving the classification and detection accuracy of breast cancer data.

Cancer mortality among immigrant populations in Ontario, 1969 through 1973.

OpenAIRE

Newman, A. M.; Spengler, R. F.

1984-01-01

Ontario is home to a sizeable, recently established immigrant population whose cancer mortality has until now remained unexamined. The province's six largest immigrant groups (British, Italian, German, Dutch, Polish and Soviet) were investigated to compare their cancer mortality experience with that prevailing in Ontario and in their countries of birth for the period 1969 through 1973. Standardized mortality ratios (SMRs) were computed from data from Statistics Canada and the World Health Org...

Dietary inflammation potential and postmenopausal breast cancer risk in a German case-control study.

Science.gov (United States)

Ge, Isabell; Rudolph, Anja; Shivappa, Nitin; Flesch-Janys, Dieter; Hébert, James R; Chang-Claude, Jenny

2015-08-01

Unhealthy dietary habits can increase the risk for serious medical conditions, such as cancer, yet the association between diet and breast cancer remains unclear. We investigated whether individual diets based on their inflammatory potential are associated with postmenopausal breast cancer risk by employing an energy-adjusted dietary inflammation index. In a German population-based case-control study, 2887 postmenopausal breast cancer patients (aged 50-74 years, first diagnosed between 2002 and 2005) and 5512 healthy age-matched controls provided information on dietary habits for the year prior to diagnosis (cases) or recruitment (controls) using a 176-items food frequency questionnaire. Associations between the energy-adjusted dietary inflammation index (E-DII) score (both as continuous variable and in quintiles) and risk for breast cancer were assessed using conditional logistic regression adjusted for potential confounders. No significant associations between the E-DII score and postmenopausal breast cancer risk were observed (adjusted OR Q5 vs Q1: 1.01, 95% CI: 0.86-1.17). Associations did not differ by estrogen receptor/progesterone receptor status (ER + PR+: adjusted OR Q5 vs Q1: 1.06, 95% CI: 0.88-1.27; ER + or PR+: OR Q5 vs Q1: 1,07, 95% CI: 0.79-1.45; ER-PR-: OR Q5 vs Q1: 0.87 95% CI: 0.63-1.20). Our results regarding E-DII are consistent with previous studies reporting a lack of association between C-reactive protein, a marker of systemic inflammation, and postmenopausal breast cancer risk. The findings may reflect a real absence of association between dietary inflammatory potential and postmenopausal cancer risk or an underestimation of association due to recall bias. Further investigation is warranted in cohort studies. Copyright © 2015 Elsevier Ltd. All rights reserved.

What cancer patients find in the internet: the visibility of evidence-based patient information - analysis of information on German websites.

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Liebl, Patrick; Seilacher, Eckart; Koester, Marie-Jolin; Stellamanns, Jan; Zell, Joerg; Hübner, Jutta

2015-01-01

The internet is an easy and always accessible source of information for cancer patients. The aim of our study was to evaluate the information provided on German websites. We developed an instrument based on criteria for patient information from the German Network for Evidence-based Medicine, the Agency for Quality in Medicine, HONcode, DISCERN, and the afgis. We simulated a patient's search and derived the websites for evaluation. We analyzed the visibility of each website and evaluated the websites using the developed instrument. We analyzed 77 websites. The highest visibility index was shown by 4 profit websites. Websites from professional societies and self-help groups have low rankings. Concerning quality, websites from non-profit providers and self-help groups are on top. Websites with a profit interest have the lowest average score. A discrepancy exists between the visibility and the quality of the analyzed websites. With the internet becoming an important source of information on cancer treatments for patients, this may lead to false information and wrong decisions. We provide a list of suggestions as to how this risk may be reduced by complementary information from the physician and from trustworthy websites. © 2015 S. Karger GmbH, Freiburg.

OPPOSITIVE METAPHORICAL MODELS IN THE GERMAN POLITICAL DISCOURSE

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Tameryan, T.Yu.

2016-06-01

Full Text Available The paper deals with the analysis of German Chancellor Angela Merkel’s metaphoric image in the German press. As a result of analysis 8 binary metaphorical constructions, verbalized by two components, one of which is positively marked (PM, the other one have been negatively (NM identified. Statistical analysis of the linguistic material allowed to conclude that the assessment of Merkel is ambivalently with a slight predominance of positive estimation.

Statistical Redundancy Testing for Improved Gene Selection in Cancer Classification Using Microarray Data

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J. Sunil Rao

2007-01-01

Full Text Available In gene selection for cancer classifi cation using microarray data, we define an eigenvalue-ratio statistic to measure a gene’s contribution to the joint discriminability when this gene is included into a set of genes. Based on this eigenvalueratio statistic, we define a novel hypothesis testing for gene statistical redundancy and propose two gene selection methods. Simulation studies illustrate the agreement between statistical redundancy testing and gene selection methods. Real data examples show the proposed gene selection methods can select a compact gene subset which can not only be used to build high quality cancer classifiers but also show biological relevance.

Statistical inquiry on the reliability of emergency diesel stations in German nuclear power plants

International Nuclear Information System (INIS)

1983-01-01

This statistic inquiry is based on 692 occurrances in 40 diesel stations of 10 German nuclear power plants. Various parameters influencing the failure behaviour of diesel stations were investigated on only significant plant-specific influences and the impact of diesel station circuitry on failure behaviour were established. According to the results of this inquiry, running time, start-up number and increasing operational experience do not apparently influence the failure behaviour of diesel stations. The expected failure probability of diesel stations varies with the different nuclear power plants. Taking into account both start-up and operational failures, (with monthly inspections and running times of up to 2 h), this value is in the range of 1.6 x 10 -2 to 1.7 x 10 -3 per application. Considering failure data of all diesel stations, the failure probability (start-up and operational failures) is 8.1 x 10 -3 per application. On account of the two common-mode failures registered, a common-mode failure probability of 10 -3 was established. The inquiry also showed that non-availability of diesel stations is essentially determined by maintenance intervals. (orig.) [de

Endangering of Businesses by the German Inheritance Tax? – An Empirical Analysis

OpenAIRE

Houben, Henriette; Maiterth, Ralf

2011-01-01

This contribution addresses the substantial tax privilege for businesses introduced by the German Inheritance Tax Act 2009. Advocates of the vast or even entire tax exemption for businesses stress the potential damage of the inheritance tax on businesses, as those often lack liquidity to meet tax liability. This submission tackles this issue empirically based on data of the German Inheritance Tax Statistics and the SOEP. The results indicate that former German inheritance tax law has not enda...

Psychiatric care in the German prison system.

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Lehmann, Marc

2012-01-01

The purpose of this paper is to describe the nature of medical care within the German penal system. German prison services provide health care for all inmates, including psychiatric care. The reached level of equivalence of care and ethical problems and resource limitations are discussed and the way of legislation in this field since 2006 reform on federal law is described. The article summarizes basic data on German prison health care for mentally ill inmates. The legislation process and factors of influence are pointed out. A description of how psychiatric care is organized in German prisons follows. It focuses on the actual legal situation including European standards of prison health care and prevention of torture, psychiatric care in German prisons themselves, self harm and addiction. Associated problems such as blood born diseases and tuberculosis are included. The interactions between prison staff and health care personal and ethic aspects are discussed. The legislation process is still going on and there is still a chance to improve psychiatric care. Mental health problems are the major challenge for prison health care. Factors such as special problems of migrants, shortage of professionals and pure statistic data are considered. The paper provides a general overview on psychiatric services in prison and names weak points and strengths of the system.

Epidemiology of Skin Cancer in the German Population: Impact of Socioeconomic and Geographic Factors.

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Augustin, J; Kis, A; Sorbe, C; Schäfer, I; Augustin, M

2018-04-06

Skin cancer being the most common cancer in Germany has shown increasing incidence in the past decade. Since mostly caused by excessive UV exposure, skin cancer is largely related to behaviour. So far, the impact of regional and sociodemographic factors on the development of skin cancer in Germany is unclear. The current study aimed to investigate the association of potential predictive factors with the prevalence of skin cancers in Germany. Nationwide ambulatory care claims data from persons insured in statutory health insurances (SHI) with malignant melanoma (MM, ICD-10 C43) and non-melanoma skin cancer (NMSC, ICD-10 C44) in the years 2009-2015 were analysed. In addition, sociodemographic population data and satellite based UV and solar radiation data were associated. Descriptive as well as multivariate (spatial) statistical analyses (for example Bayes' Smoothing) were conducted on county level. Data from 70.1 million insured persons were analysed. Age standardized prevalences per 100,000 SHI insured persons for MM and NMSC were 284.7 and 1126.9 in 2009 and 378.5 and 1708.2 in 2015. Marked regional variations were observed with prevalences between 32.9% and 51.6%. Multivariate analysis show statistically significant positive correlations between higher income and education, and MM/NMSC prevalence. Prevalence of MM and NMSC in Germany shows spatio-temporal dynamics. Our results show that regional UV radiation, sunshine hours and sociodemographic factors have significant impact on skin cancer prevalence in Germany. Individual behaviour obviously is a major determinant which should be subject to preventive interventions. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

German Studies in America. German Studies Notes.

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Sander, Volkmar; Osterle, Heinz D.

This volume contains two papers, "German Studies in America," by Volkmar Sander, and "Historicism, Marxism, Structuralism: Ideas for German Culture Courses," by Heinz D. Osterle. The first paper discusses the position of German studies in the United States today. The greatest challenge comes from low enrollments; therefore,…

Order-specific fertility estimates based on perinatal statistics and statistics on out-of-hospital births

OpenAIRE

Kreyenfeld, Michaela; Peters, Frederik; Scholz, Rembrandt; Wlosnewski, Ines

2014-01-01

Until 2008, German vital statistics has not provided information on biological birth order. We have tried to close part of this gap by providing order-specific fertility rates generated from Perinatal Statistics and statistics on out-of-hospital births for the period 2001-2008. This investigation has been published in Comparative Population Studies (CPoS) (see Kreyenfeld, Scholz, Peters and Wlosnewski 2010). The CPoS-paper describes how data from the Perinatal Statistics and statistics on out...

Walking, bicycling, and sports in postmenopausal breast cancer survivors--results from a German patient cohort study.

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Bock, Christina; Schmidt, Martina E; Vrieling, Alina; Chang-Claude, Jenny; Steindorf, Karen

2013-06-01

Physical activity (PA) is increasingly discussed as a means to achieve both physical and psychological benefits for breast cancer patients and survivors. However, little is known about activity-specific PA behavior following diagnosis. Our objectives were to describe sports and active transportation in the course of breast cancer and to identify factors associated with these activities. We used data from a German cohort study including 1067 postmenopausal breast cancer survivors aged 50-75 years. Data were collected about walking and bicycling for transportation purposes and sports before diagnosis, during therapy, and 1 year after surgery. Associations between these activities and clinical, behavioral, and social characteristics were analyzed with logistic regression. The proportions of physically active women decreased significantly during therapy compared with before diagnosis (walking: 75.1% vs. 89.7%; bicycling: 19.3% vs. 56.5%; sports: 14.8% vs. 64.5%; all p sport. Chemotherapy/radiotherapy was negatively associated with sports (odds ratio [OR]: 0.35 [0.17-0.73]) but positively associated with walking during therapy (OR: 2.08 [1.04-4.15]). Although sociodemographic factors showed weak associations with PA, participation in rehabilitation increased the likelihood for bicycling (OR: 1.48 [1.06-2.09]) and sports (OR: 1.88 [1.38-2.58]) 1 year after surgery. The majority of women stopped exercising and bicycling during breast cancer therapy. Interventions promoting in particular moderate activities after breast cancer diagnosis are required for this population. Increasing participation in rehabilitation might help to increase the proportion of women who bicycle and engage in sports after breast cancer diagnosis. Copyright © 2012 John Wiley & Sons, Ltd.

… but You Are Not German." -- Afro-German Culture and Literature in the German Language Classroom

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Schenker, Theresa; Munro, Robert

2016-01-01

Units and classes dedicated to multiculturalism in Germany have predominantly focused on Turkish-German literature and culture. Afro-Germans have been a minority whose culture and literature have only marginally been included in German classes, even though Afro-Germans have been a part of Germany for centuries and have undergone efforts at…

Marlene Dietrich in the German Classroom: A German Film Project--Humanities through the Golden Age of German Cinema.

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Flippo, Hyde

1993-01-01

Marlene Dietrich and other classic performers of German cinema can serve to open up a whole new realm for students of German, at secondary and postsecondary levels. By researching and viewing German and American film classics, students have opportunity to learn more about German language and an important element of German culture that has had…

Socio-demographic characteristics of participation in the opportunistic German cervical cancer screening programme: results from the EPIC-Heidelberg cohort.

Science.gov (United States)

Seidel, David; Becker, Nikolaus; Rohrmann, Sabine; Nimptsch, Katharina; Linseisen, Jakob

2009-04-01

To analyse participation in the German cervical cancer screening programme by socio-demographic characteristics. In the EPIC-Heidelberg cohort study 13,612 women aged 35-65 years were recruited between 1994 and 1998. Follow-up questionnaires were used to analyse participation in cervical cancer screening. Subjects were categorised according to age (birth cohort), education, vocational training, employment status, marital status and household size. Associations between socio-demographic characteristics and participation in cervical cancer screening were analysed using multinomial logistic regression. Females of the oldest and middle birth cohort were less likely to be screened compared to the youngest birth cohort. Less-educated women and those with a low-level secondary school degree had a decreased likelihood of undergoing screening in comparison to better educated women. Married women and women living in households with four or more persons were more likely to participate in the screening programme than single women or women living alone. Employment status did not modify participation in cervical cancer screening. Knowledge on the characteristics of women with a lower attendance to cervical cancer screening could be used to improve the effectiveness of the current (opportunistic) programme by dedicated health promotion programmes. However, an organized screening programme with written invitation of all eligible women would be the preferred option.

Intelligibility of Standard German and Low German to Speakers of Dutch

NARCIS (Netherlands)

Gooskens, C.S.; Kürschner, Sebastian; van Bezooijen, R.

2011-01-01

This paper reports on the intelligibility of spoken Low German and Standard German for speakers of Dutch. Two aspects are considered. First, the relative potential for intelligibility of the Low German variety of Bremen and the High German variety of Modern Standard German for speakers of Dutch is

Statistics

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Links to sources of cancer-related statistics, including the Surveillance, Epidemiology and End Results (SEER) Program, SEER-Medicare datasets, cancer survivor prevalence data, and the Cancer Trends Progress Report.

Associations between adjuvant radiotherapy and different causes of death in a German breast cancer cohort.

Science.gov (United States)

Obi, Nadia; Eulenburg, Christine; Seibold, Petra; Eilber, Ursula; Thöne, Kathrin; Behrens, Sabine; Chang-Claude, Jenny; Flesch-Janys, Dieter

2018-04-01

Studies of cohorts of breast cancer (BC) patients diagnosed before 1990 showed radiotherapy (RT) to be associated with increased cardiovascular (CVD) and lung cancer mortality many years after diagnosis. In the late 1990s, improvements in RT planning techniques reduced radiation doses to normal tissues. Recent studies did not consistently report higher RT-related mortality for CVD and second cancers. Aim of the study was to analyze specific causes of death after 3D-conformal RT in a recent BC cohort. Stage I-III BC patients diagnosed 2001-2005 and enrolled in the population based MARIEplus study were followed-up for 11.9 years (median). Associations between adjuvant RT and cause-specific mortality were analyzed by using competing risks models, yielding subdistribution hazard ratios (SHR) for RT directly related to cumulative incidences. Models were adjusted for differences in baseline characteristics applying inverse-probability-of-treatment-weighting (IPTW). Of the 2951 patients, 2439 (83.0%) received RT. No significant association of RT with lung cancer mortality (SHR IPTW 0.88, 0.35-2.12), other cancer mortality (SHR IPTW 1.04, 95% CI 0.62-1.73) or cardiac mortality was observed (SHR IPTW 1.57, 0.75-3.29). Mortality from lung and other diseases were significantly lower in irradiated women (SHR IPTW 0.39, 95% CI 0.17-0.90 and SHR IPTW 0.58, 95% CI 0.34-0.97, respectively). In line with recent studies, 3D-conformal RT did not significantly increase mortality from non-BC causes in the German MARIEplus cohort. Since long-term data are still sparse and event rates low in BC-cohorts, who received modern RT, investigation of possible late RT effects on mortality beyond 14 years of follow-up is warranted. Copyright © 2017 Elsevier Ltd. All rights reserved.

ANALYSIS OF THE INCIDENCE OF PROSTATE CANCER IN THE ROSTOV REGION FOR THE YEARS 2001–2016: SPATIOTEMPORAL STATISTICS

Directory of Open Access Journals (Sweden)

O. E. Arhipova

2017-01-01

Full Text Available Introduction. Oncological diseases is a serious medico-social problem of modern society. The article presents the analysis of prostate cancer morbidity with consideration of regional health level differences.Objective. To conduct spatial-temporal analysis of prostate cancer incidence in Rostov region; to identify areas with a statistically significant increase in the incidence of prostate cancer; to identify regional differences (environmental determinism in the development of cancer in the southern Federal district.Materials and methods. We’ve analysed incidence of prostate cancer in the Rostov region for the period of 2001-2016. The analysis has been performed using tools spatio-temporal statistics on software ArcGis 10 *.Results. Areas and cities of Rostov region with a statistically significant increase in prostate cancer incidence were identified. It has been shown that in the regions and cities of the Rostov region with a low level of medical-ecological safety had a statistically significant increase in prostate cancer incidenceConclusions. The results can serve as a basis for the directional analysis of factors causing increased risk of cancer and development on this basis strategies for monitoring and prevention of cancer diseases in the Rostov region.

Inheritance tax-exempt transfer of German businesses: Imperative or unjustified subsidy? An empirical analysis

OpenAIRE

Houben, Henriette; Maiterth, Ralf

2009-01-01

This contribution addresses the substantial tax subsidies for businesses introduced by the German Inheritance Tax Act 2009. Advocates in favour of the vast or even entire tax exemption for businesses stress the potential damage of the inheritance tax on businesses, as those often lack liquid assets to meet tax liability. This submission tackles this issue empirically based on data of the German Inheritance Tax Statistics and the SOEP. The results indicate that former German inheritance tax la...

What Gives Meaning in Life to Patients With Advanced Cancer? A Comparison Between Spanish, German, and Swiss Patients.

Science.gov (United States)

Tomás-Sábado, Joaquín; Villavicencio-Chávez, Christian; Monforte-Royo, Cristina; Guerrero-Torrelles, Mariona; Fegg, Martin Johannes; Balaguer, Albert

2015-12-01

Meaning in life (MiL) is a construct that varies across individuals, situations, cultures, and countries, and protects against emotional distress at the end of life. To examine MiL in inpatients with advanced cancer from Barcelona, Spain, and to compare the findings with those obtained in German and Swiss samples. This was a cross-sectional study in which the Schedule for Meaning in Life Evaluation (SMiLE) was administered. The SMiLE asks respondents to list individual areas that give meaning in their lives and then to rate their current level of importance and satisfaction with the listed areas. A total of 101 inpatients completed the SMiLE. The Index of Satisfaction was 76.8 ± 21.1, the Index of Weighting was 88.0 ± 13.0, and the Index of Weighted Satisfaction was 76.9 ± 20.7. Family, partnership, well-being, and friends were the four areas listed by the largest proportion of Spanish patients. Compared with the German sample, Spanish patients were more likely to list well-being (P German and Swiss counterparts, the Spanish patients listed more areas involving interpersonal relationships. Interpersonal relationships, at both the family and wider social level, are reported to be the areas that give the greatest MiL to these patients. These aspects, therefore, should be considered when drawing up care plans designed to help patients achieve the maximum possible comfort and quality of life. Copyright © 2015 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

Development of a statistical model for cervical cancer cell death with irreversible electroporation in vitro.

Science.gov (United States)

Yang, Yongji; Moser, Michael A J; Zhang, Edwin; Zhang, Wenjun; Zhang, Bing

2018-01-01

The aim of this study was to develop a statistical model for cell death by irreversible electroporation (IRE) and to show that the statistic model is more accurate than the electric field threshold model in the literature using cervical cancer cells in vitro. HeLa cell line was cultured and treated with different IRE protocols in order to obtain data for modeling the statistical relationship between the cell death and pulse-setting parameters. In total, 340 in vitro experiments were performed with a commercial IRE pulse system, including a pulse generator and an electric cuvette. Trypan blue staining technique was used to evaluate cell death after 4 hours of incubation following IRE treatment. Peleg-Fermi model was used in the study to build the statistical relationship using the cell viability data obtained from the in vitro experiments. A finite element model of IRE for the electric field distribution was also built. Comparison of ablation zones between the statistical model and electric threshold model (drawn from the finite element model) was used to show the accuracy of the proposed statistical model in the description of the ablation zone and its applicability in different pulse-setting parameters. The statistical models describing the relationships between HeLa cell death and pulse length and the number of pulses, respectively, were built. The values of the curve fitting parameters were obtained using the Peleg-Fermi model for the treatment of cervical cancer with IRE. The difference in the ablation zone between the statistical model and the electric threshold model was also illustrated to show the accuracy of the proposed statistical model in the representation of ablation zone in IRE. This study concluded that: (1) the proposed statistical model accurately described the ablation zone of IRE with cervical cancer cells, and was more accurate compared with the electric field model; (2) the proposed statistical model was able to estimate the value of electric

Inferential Statistics from Black Hispanic Breast Cancer Survival Data

Directory of Open Access Journals (Sweden)

Hafiz M. R. Khan

2014-01-01

Full Text Available In this paper we test the statistical probability models for breast cancer survival data for race and ethnicity. Data was collected from breast cancer patients diagnosed in United States during the years 1973–2009. We selected a stratified random sample of Black Hispanic female patients from the Surveillance Epidemiology and End Results (SEER database to derive the statistical probability models. We used three common model building criteria which include Akaike Information Criteria (AIC, Bayesian Information Criteria (BIC, and Deviance Information Criteria (DIC to measure the goodness of fit tests and it was found that Black Hispanic female patients survival data better fit the exponentiated exponential probability model. A novel Bayesian method was used to derive the posterior density function for the model parameters as well as to derive the predictive inference for future response. We specifically focused on Black Hispanic race. Markov Chain Monte Carlo (MCMC method was used for obtaining the summary results of posterior parameters. Additionally, we reported predictive intervals for future survival times. These findings would be of great significance in treatment planning and healthcare resource allocation.

The electricity supply industry in the German Federal Republic in the year 1974

International Nuclear Information System (INIS)

Anon.

1975-01-01

The present report continues the series of the annual reports issued so far, in the same form and arrangement of the available statistical material, which have been published in 'Elektrizitaetswirtschaft' since 1950 and as special publication. On the basis of official data the report gives a statistical review of public electricity supply, the industrial private undertakings and the power supply to the German Federal Railways. By combining these three groups - after omitting any overlap of the available data - an overall review of the development of electricity supply in the whole of the German Federal Republic is made possible. (orig.) [de

A statistical framework for evaluating neural networks to predict recurrent events in breast cancer

Science.gov (United States)

Gorunescu, Florin; Gorunescu, Marina; El-Darzi, Elia; Gorunescu, Smaranda

2010-07-01

Breast cancer is the second leading cause of cancer deaths in women today. Sometimes, breast cancer can return after primary treatment. A medical diagnosis of recurrent cancer is often a more challenging task than the initial one. In this paper, we investigate the potential contribution of neural networks (NNs) to support health professionals in diagnosing such events. The NN algorithms are tested and applied to two different datasets. An extensive statistical analysis has been performed to verify our experiments. The results show that a simple network structure for both the multi-layer perceptron and radial basis function can produce equally good results, not all attributes are needed to train these algorithms and, finally, the classification performances of all algorithms are statistically robust. Moreover, we have shown that the best performing algorithm will strongly depend on the features of the datasets, and hence, there is not necessarily a single best classifier.

Mortality from internal and external radiation exposure in a cohort of male German uranium millers, 1946-2008

Energy Technology Data Exchange (ETDEWEB)

Kreuzer, M.; Dufey, F.; Schnelzer, M.; Sogl, M.; Walsh, L. [Federal Office for Radiation Protection, Neuherberg (Germany). Dept. of Radiation Protection and Health; Laurier, D. [Institute for Radiological Protection and Nuclear Safety (IRSN), Paris (France); Nowak, D. [LMU Muenchen (Germany). Inst. for Occupational Medicine and Environmental Medicine; Marsh, J.W. [Public Health England, Chilton, Didcot (United Kingdom)

2015-05-15

To examine exposure-response relationships between ionizing radiation and several mortality outcomes in a subgroup of 4,054 men of the German uranium miner cohort study, who worked between 1946 and 1989 in milling facilities, but never underground or in open pit mines. Mortality follow-up was from 1946 to 2008, accumulating 158,383 person-years at risk. Cumulative exposure to radon progeny in working level months (WLM) (mean = 8, max = 127), long-lived radionuclides from uranium ore dust in kBqh/m{sup 3} (mean = 3.9, max = 132), external gamma radiation in mSv (mean = 26, max = 667) and silica dust was estimated by a comprehensive job-exposure matrix. Internal Poisson regression models were applied to estimate the linear excess relative risk (ERR) per unit of cumulative exposure. Overall, a total of 457, 717 and 111 deaths occurred from malignant cancer, cardiovascular diseases and non-malignant respiratory diseases, respectively. Uranium ore dust and silica dust were not associated with mortality from any of these disease groups. A statistically significant relationship between cumulative radon exposure and mortality from all cancers (ERR/100 WLM = 1.71; p = 0.02), primarily due to lung cancer (n = 159; ERR/100 WLM = 3.39; p = 0.05), was found. With respect to cumulative external gamma radiation, an excess of mortality of solid cancers (n = 434; ERR/Sv = 1.86; p = 0.06), primarily due to stomach cancer (n = 49, ERR/Sv = 10.0; p = 0.12), was present. The present findings show an excess mortality from lung cancer due to radon exposure and from solid cancers due to external gamma radiation in uranium millers that was not statistically significant. Exposure to uranium was not associated with any cause of death, but absorbed organ doses were estimated to be low.

Mortality from internal and external radiation exposure in a cohort of male German uranium millers, 1946-2008

International Nuclear Information System (INIS)

Kreuzer, M.; Dufey, F.; Schnelzer, M.; Sogl, M.; Walsh, L.; Nowak, D.

2015-01-01

To examine exposure-response relationships between ionizing radiation and several mortality outcomes in a subgroup of 4,054 men of the German uranium miner cohort study, who worked between 1946 and 1989 in milling facilities, but never underground or in open pit mines. Mortality follow-up was from 1946 to 2008, accumulating 158,383 person-years at risk. Cumulative exposure to radon progeny in working level months (WLM) (mean = 8, max = 127), long-lived radionuclides from uranium ore dust in kBqh/m 3 (mean = 3.9, max = 132), external gamma radiation in mSv (mean = 26, max = 667) and silica dust was estimated by a comprehensive job-exposure matrix. Internal Poisson regression models were applied to estimate the linear excess relative risk (ERR) per unit of cumulative exposure. Overall, a total of 457, 717 and 111 deaths occurred from malignant cancer, cardiovascular diseases and non-malignant respiratory diseases, respectively. Uranium ore dust and silica dust were not associated with mortality from any of these disease groups. A statistically significant relationship between cumulative radon exposure and mortality from all cancers (ERR/100 WLM = 1.71; p = 0.02), primarily due to lung cancer (n = 159; ERR/100 WLM = 3.39; p = 0.05), was found. With respect to cumulative external gamma radiation, an excess of mortality of solid cancers (n = 434; ERR/Sv = 1.86; p = 0.06), primarily due to stomach cancer (n = 49, ERR/Sv = 10.0; p = 0.12), was present. The present findings show an excess mortality from lung cancer due to radon exposure and from solid cancers due to external gamma radiation in uranium millers that was not statistically significant. Exposure to uranium was not associated with any cause of death, but absorbed organ doses were estimated to be low.

Investigating the genetic relationship between Alzheimer’s disease and cancer using GWAS summary statistics

NARCIS (Netherlands)

Feng, Yen Chen Anne; Cho, Kelly; Lindstrom, Sara; Kraft, Peter; Cormack, Jean; Blalock, Kendra; Campbell, Peter T.; Casey, Graham; Conti, David V.; Edlund, Christopher K.; Figueiredo, Jane; James Gauderman, W.; Gong, Jian; Green, Roger C.; Gruber, Stephen B.; Harju, John F.; Harrison, Tabitha A.; Jacobs, Eric J; Jenkins, Mark A.; Jiao, Shuo; Li, Li; Lin, Yi; Manion, Frank J.; Moreno, Victor; Mukherjee, Bhramar; Peters, Ulrike; Raskin, Leon; Schumacher, Fredrick R.; Seminara, Daniela; Severi, Gianluca; Stenzel, Stephanie L.; Thomas, Duncan C.; Hopper, John L.; Southey, Melissa C.; Makalic, Enes; Schmidt, Daniel F.; Fletcher, Olivia; Peto, Julian; Gibson, Lorna; Dos-Santos-Silva, Isabel; Hunter, David J.; Lindström, Sara; Kraft, Peter; Ahsan, Habib; Whittemore, Alice S.; Waisfisz, Quinten; Meijers-Heijboer, Hanne; Adank, Muriel A.; van der Luijt, Rob B.; Uitterlinden, Andre G; Hofman, Albert; Meindl, Alfons; Schmutzler, Rita K.; Müller-Myhsok, Bertram; Lichtner, Peter; Nevanlinna, Heli; Muranen, Taru A.; Aittomäki, Kristiina; Blomqvist, Carl; Chang-Claude, Jenny; Hein, Rebecca; Dahmen, Norbert; Beckman, Lars; Crisponi, Laura; Hall, Per; Czene, Kamila; Irwanto, Astrid; Liu, Jianjun; Easton, Douglas F.; Turnbull, Clare A.; Rahman, Nazneen; Kote-Jarai, Zsofia; Muir, Kenneth; Giles, Graham G.; Severi, Gianluca; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Wiklund, Fredrik; Gronberg, Henrik; Haiman, Christopher; Schumacher, Fred; Travis, Ruth C.; Riboli, Elio; Kraft, Peter; Hunter, David J.; Gapstur, Susan M.; Berndt, Sonja I.; Chanock, Stephen J.; Han, Younghun; Su, Li; Wei, Yongyue; Hung, Rayjean J.; Brhane, Yonathan; McLaughlin, John; Brennan, Paul; McKay, James D.; Bickeböller, Heike; Rosenberger, Albert; Houlston, Richard S.; Caporaso, Neil E; Landi, Maria Teresa; Heinrich, Joachim; Risch, Angela; Wu, Xifeng; Ye, Yuanqing; Christiani, David C.; Amos, Christopher I; Liang, Liming; Driver, Jane A.; IGAP Consortium, Colorectal Transdisciplinary Study (CORECT); Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE)

2017-01-01

Growing evidence from both epidemiology and basic science suggest an inverse association between Alzheimer’s disease (AD) and cancer. We examined the genetic relationship between AD and various cancer types using GWAS summary statistics from the IGAP and GAME-ON consortia. Sample size ranged from

[Cause-of-death statistics and ICD, quo vadis?

Science.gov (United States)

Eckert, Olaf; Vogel, Ulrich

2018-07-01

The International Statistical Classification of Diseases and Related Health Problems (ICD) is the worldwide binding standard for generating underlying cause-of-death statistics. What are the effects of former revisions of the ICD on underlying cause-of-death statistics and which opportunities and challenges are becoming apparent in a possible transition process from ICD-10 to ICD-11?This article presents the calculation of the exploitation grade of ICD-9 and ICD-10 in the German cause-of-death statistics and quality of documentation. Approximately 67,000 anonymized German death certificates are processed by Iris/MUSE and official German cause-of-death statistics are analyzed.In addition to substantial changes in the exploitation grade in the transition from ICD-9 to ICD-10, regional effects become visible. The rate of so-called "ill-defined" conditions exceeds 10%.Despite substantial improvement of ICD revisions there are long-known deficits in the coroner's inquest, filling death certificates and quality of coding. To make better use of the ICD as a methodological framework for mortality statistics and health reporting in Germany, the following measures are necessary: 1. General use of Iris/MUSE, 2. Establishing multiple underlying cause-of-death statistics, 3. Introduction of an electronic death certificate, 4. Improvement of the medical assessment of cause of death.Within short time the WHO will release the 11th revision of the ICD that will provide additional opportunities for the development of underlying cause-of-death statistics and their use in science, public health and politics. A coordinated effort including participants in the process and users is necessary to meet the related challenges.

Cancer-risk benefits of clean fuel technology and policy. A statistical analysis

Energy Technology Data Exchange (ETDEWEB)

Gallagher, Paul [Economics Department, 481 Heady Hall, Iowa State University, Ames, IA 50011 (United States); Lazarus, William [Applied Economics Department, 253 COB, University of Minnesota, St. Paul, MN 55455 (United States); Shapouri, Hosein; Conway, Roger; Duffield, James [Office of Energy Policy and New Uses, 400 Independence Avenue, SW Rm. 4059 So. Bldg, United States Department of Agriculture, WA, DC 20250 (United States)

2009-12-15

The hypothesis of this study is that there is a statistical relationship between the lung cancer mortality rate and the intensity of fuel consumption (measured in gallons/square mile) at a particular location. We estimate cross-section regressions of the mortality rate due to lung cancer against the intensity of fuel consumption using local data for the entire US, before the US Clean Air Act (CAA) in 1974 and after the most recent policy revisions in 2004. The cancer rate improvement estimate suggests that up to 10 lung cancer deaths per 100,000 residents are avoided in the largest urban areas with highest fuel consumption per square mile. In New York City, for instance, the mortality reduction may be worth about USD 5.7 billion annually. Across the US, the estimated value of statistical life (VSL) benefit is USD 27.2 billion annually. There are likely three inseparable reasons that contributed importantly to this welfare improvement. First, the CAA regulations mandated reduction in specific carcinogenic chemicals or smog components. Second, technologies such as the catalytic converter (CC) and low-particulate diesel engine were adopted. Third, biofuels have had important roles, making the adoption of clean air technology possible and substituting for high emission fuels. (author)

Cancer-risk benefits of clean fuel technology and policy: A statistical analysis

Energy Technology Data Exchange (ETDEWEB)

Gallagher, Paul, E-mail: paulg@iastate.ed [Economics Department, 481 Heady Hall, Iowa State University, Ames, IA 50011 (United States); Lazarus, William [Applied Economics Department, 253 COB, University of Minnesota, St. Paul, MN 55455 (United States); Shapouri, Hosein; Conway, Roger; Duffield, James [Office of Energy Policy and New Uses, 400 Independence Avenue, SW (Rm. 4059 So. Bldg), United States Department of Agriculture, WA, DC 20250 (United States)

2009-12-15

The hypothesis of this study is that there is a statistical relationship between the lung cancer mortality rate and the intensity of fuel consumption (measured in gallons/square mile) at a particular location. We estimate cross-section regressions of the mortality rate due to lung cancer against the intensity of fuel consumption using local data for the entire US, before the US Clean Air Act (CAA) in 1974 and after the most recent policy revisions in 2004. The cancer rate improvement estimate suggests that up to 10 lung cancer deaths per 100,000 residents are avoided in the largest urban areas with highest fuel consumption per square mile. In New York City, for instance, the mortality reduction may be worth about $5.7 billion annually. Across the US, the estimated value of statistical life (VSL) benefit is $27.2 billion annually. There are likely three inseparable reasons that contributed importantly to this welfare improvement. First, the CAA regulations mandated reduction in specific carcinogenic chemicals or smog components. Second, technologies such as the catalytic converter (CC) and low-particulate diesel engine were adopted. Third, biofuels have had important roles, making the adoption of clean air technology possible and substituting for high emission fuels.

Cancer-risk benefits of clean fuel technology and policy: A statistical analysis

International Nuclear Information System (INIS)

Gallagher, Paul; Lazarus, William; Shapouri, Hosein; Conway, Roger; Duffield, James

2009-01-01

The hypothesis of this study is that there is a statistical relationship between the lung cancer mortality rate and the intensity of fuel consumption (measured in gallons/square mile) at a particular location. We estimate cross-section regressions of the mortality rate due to lung cancer against the intensity of fuel consumption using local data for the entire US, before the US Clean Air Act (CAA) in 1974 and after the most recent policy revisions in 2004. The cancer rate improvement estimate suggests that up to 10 lung cancer deaths per 100,000 residents are avoided in the largest urban areas with highest fuel consumption per square mile. In New York City, for instance, the mortality reduction may be worth about $5.7 billion annually. Across the US, the estimated value of statistical life (VSL) benefit is $27.2 billion annually. There are likely three inseparable reasons that contributed importantly to this welfare improvement. First, the CAA regulations mandated reduction in specific carcinogenic chemicals or smog components. Second, technologies such as the catalytic converter (CC) and low-particulate diesel engine were adopted. Third, biofuels have had important roles, making the adoption of clean air technology possible and substituting for high emission fuels.

Endangering of Businesses by the German Inheritance Tax? – An Empirical Analysis

Directory of Open Access Journals (Sweden)

Henriette Houben

2011-04-01

Full Text Available This contribution addresses the substantial tax privilege for businesses introduced by the German Inheritance Tax Act 2009. Advocates of the vast or even entire tax exemption for businesses stress the potential damage of the inheritance tax on businesses, as those often lack liquidity to meet tax liability. This submission tackles this issue empirically based on data of the German Inheritance Tax Statistics and the SOEP. The results indicate that former German inheritance tax law has not endangered transferred businesses. Hence, there is no need for the tremendous tax privilege for businesses in current German inheritance tax law. An alternative flat inheritance tax without tax privileges, which meets revenue neutrality per tax class according to current tax law, provokes in some cases relative high tax loads which might trouble businesses.

[German validation of the Acute Cystitis Symptom Score].

Science.gov (United States)

Alidjanov, J F; Pilatz, A; Abdufattaev, U A; Wiltink, J; Weidner, W; Naber, K G; Wagenlehner, F

2015-09-01

The Uzbek version of the Acute Cystitis Symptom Score (ACSS) was developed as a simple self-reporting questionnaire to improve diagnosis and therapy of women with acute cystitis (AC). The purpose of this work was to validate the ACSS in the German language. The ACSS consists of 18 questions in four subscales: (1) typical symptoms, (2) differential diagnosis, (3) quality of life, and (4) additional circumstances. Translation of the ACSS into German was performed according to international guidelines. For the validation process 36 German-speaking women (age: 18-90 years), with and without symptoms of AC, were included in the study. Classification of participants into two groups (patients or controls) was based on the presence or absence of typical symptoms and significant bacteriuria (≥ 10(3) CFU/ml). Statistical evaluations of reliability, validity, and predictive ability were performed. ROC curve analysis was performed to assess sensitivity and specificity of ACSS and its subscales. The Mann-Whitney's U test and t-test were used to compare the scores of the groups. Of the 36 German-speaking women (age: 40 ± 19 years), 19 were diagnosed with AC (patient group), while 17 women served as controls. Cronbach's α for the German ACSS total scale was 0.87. A threshold score of ≥ 6 points in category 1 (typical symptoms) significantly predicted AC (sensitivity 94.7%, specificity 82.4%). There were no significant differences in ACSS scores in patients and controls compared to the original Uzbek version of the ACSS. The German version of the ACSS showed a high reliability and validity. Therefore, the German version of the ACSS can be reliably used in clinical practice and research for diagnosis and therapeutic monitoring of patients suffering from AC.

French pollution and German lignite

International Nuclear Information System (INIS)

Foos, Jacques

2015-01-01

After having recalled that the German energy transition is based on a complete shutting down of nuclear power stations to replace them by renewable energy sources on the one hand, and by coal (lignite, i.e. the dirtiest coal) and gas on the other hand to compensate the intermittency of the former ones, this article notices that pollution peaks occurred in France when an eastern of north-eastern wind was blowing, and not in case of western wind. The author then wanders whether this pollution comes from Germany, and more particularly from the releases of lignite-fuelled power stations. Then, the author comments the high level of pollution associated with coal extraction and exploitation in Germany, causing thousands of deaths and resulting in lung diseases or cancers, myocardial infractions. The author then makes a parallel between, on the one hand, the ignorance of this German pollution and, on the other hand, evacuation measures around Fukushima for a radioactivity which the author considers as less dangerous in terms of life expectancy

Validation of the "Quality of Life in Life-Threatening Illness--Family Carer Version" (QOLLTI-F) in German-speaking carers of advanced cancer patients.

Science.gov (United States)

Schur, Sophie; Ebert-Vogel, Alexandra; Amering, Michaela; Masel, Eva Katharina; Neubauer, Marie; Schrott, Andrea; Sibitz, Ingrid; Watzke, Herbert; Schrank, Beate

2014-10-01

Palliative care is a multidisciplinary approach that focuses on the improvement of quality of life (QOL) of patients as well as their families. QOL research in palliative care has so far primarily focused on patients, but interest in the QOL of their relatives is increasing. For instruments measuring QOL in relatives, data on psychometric properties are often limited, and so far, none has been available in German. This study translates and validates the "Quality of Life in Life-Threatening Illness-Family Carer Version" (QOLLTI-F) in German-speaking carers of advanced cancer patients. The QOLLTI-F was translated from English into German according to the World Health Organisation's recommendations and validated in informal caregivers of terminally ill cancer patients of three Viennese hospitals. Hope was measured to assess concurrent validity; traumatic stress, anxiety, depression and subjective burden were measured to assess discriminant validity. Internal consistency, test-retest reliability and discriminative power were established. The scale's factor structure was explored using a set of factor analyses. Of the 308 caregivers participating in the study, 42 completed the QOLLTI-F retest after a mean of 5 days. The internal consistency was α = 0.85 for the overall scale, Pearson correlation between test and retest lay at r = 0.92. As expected, a significant positive correlation was found with hope (r = 0.40) and significant negative correlations with traumatic stress (r = -0.41), depression (r = -0.51), anxiety (r = -0.52) and overall subjective burden (r = -0.55). The original seven-factor structure was not reproduced, but the scale showed a stable four-factor structure with factors capturing (1) feelings about carers' own life, (2) professional care, (3) interaction with the patient and others and (3) carers' outlook on life. This study provides a sound translation and validation of the first QOL assessment tool for caregivers of

Rare earth germanates

International Nuclear Information System (INIS)

Bondar', I.A.; Vinogradova, N.V.; Dem'yanets, L.N.

1983-01-01

Rare earth germanates attract close attention both as an independent class of compounds and analogues of a widely spread class of natural and synthetic minerals. The methods of rare earth germanate synthesis (solid-phase, hydrothermal) are considered. Systems on the basis of germanium and rare earth oxides, phase diagrams, phase transformations are studied. Using different chemical analysese the processes of rare earth germanate formation are investigated. IR spectra of alkali and rare earth metal germanates are presented, their comparative analysis being carried out. Crystal structures of the compounds, lattice parameters are studied. Fields of possible application of rare earth germanates are shown

Rare earth germanates

International Nuclear Information System (INIS)

Bondar', I.A.; Vinogradova, N.V.; Dem'yanets, L.N.

1983-01-01

From the viewpoint of structural chemistry and general regularities controlling formation reactions of compounds and phases in melts, solid and gaseous states, recent achievements in the chemistry of rare earth germanates are generalized. Methods of synthesizing germanates, systems on the base of germanium oxides and rare earths are considered. The data on crystallochemical characteristics are tabulated. Individual compounds of scandium germanate are also characterized. Processes of germanate formation using the data of IR-spectroscopy, X-ray phase analysis are studied. The structure and morphotropic series of rare earth germanates and silicates are determined. Fields of their present and possible future application are considered

Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors: data from the German CVSS-study.

Science.gov (United States)

Faber, J; Wingerter, A; Neu, M A; Henninger, N; Eckerle, S; Münzel, T; Lackner, K J; Beutel, M E; Blettner, M; Rathmann, W; Peters, A; Meisinger, C; Linkohr, B; Neuhauser, H; Kaatsch, P; Spix, C; Schneider, A; Merzenich, H; Panova-Noeva, M; Prochaska, J H; Wild, P S

2018-05-01

The cardiac and vascular late sequelae in long-term survivors of childhood cancer (CVSS)-study aimed to quantify the prevalence of cardiovascular risk factors (CVRF) and cardiovascular disease (CVD) in German childhood cancer survivors (CCS). In the CVSS-study (NCT02181049), 1002 CCS (age range 23-48 years) diagnosed with neoplasia prior to 15 years of age between 1980 and 1990 prospectively underwent a systematic, standardized clinical and laboratory cardiovascular screening, identical to the population-based Gutenberg Health Study (GHS) cohort. For 951 individuals, prevalences of CVRF and CVD were primarily compared to the GHS sample and to two further German population-based cohorts. Using log-binomial regression models, an increased risk for occurrence of arterial hypertension [relative risk (RR) 1.38, 95% confidence interval (95% CI 1.21-1.57)] and dyslipidaemia [RR 1.26 (95% CI 1.12-1.42)] was found. This indicates a premature occurrence compared to the general population of approximately 6 and 8 years, respectively [rate advancement period estimator, RAPhypertension 5.75 (95% CI 3.5-8.0) and RAPdyslipidaemia 8.16 (95% CI 4.4-11.9)]. Overall, no differences were observed for obesity and diabetes. Overt CVD was present in 4.5% (95% CI 3.0-6.6%) of CCS [RR 1.89 (95% CI 1.34-2.66), RAPCVD 7.9 (95% CI 4.1-11.7)], of which the most frequent entities were congestive heart failure and venous thromboembolism. Prevalences of CVRF and CVD increased with age without reaching a plateau over time. This large CCS screening examination revealed consistently in comparison to three population samples a considerably increased risk for premature CVD. The findings in these young adult CCS indicate a high burden of cardiovascular morbidity and mortality in the long term. NCT02181049.

Statistical classifiers on multifractal parameters for optical diagnosis of cervical cancer

Science.gov (United States)

Mukhopadhyay, Sabyasachi; Pratiher, Sawon; Kumar, Rajeev; Krishnamoorthy, Vigneshram; Pradhan, Asima; Ghosh, Nirmalya; Panigrahi, Prasanta K.

2017-06-01

An augmented set of multifractal parameters with physical interpretations have been proposed to quantify the varying distribution and shape of the multifractal spectrum. The statistical classifier with accuracy of 84.17% validates the adequacy of multi-feature MFDFA characterization of elastic scattering spectroscopy for optical diagnosis of cancer.

Argument about the climatological-meteorological data base of the German Risk Study on Nuclear Power Plants

International Nuclear Information System (INIS)

Kumm, H.

1984-01-01

The Ecological Institute's doubts about the representativeness of the climatological-meteorological data base of the German Risk Study concludes that this data base with its 115 'weather sequences' combined with 36 'wind directions' has no defined reference period. The complementary frequency distributions of the German Risk Study do not, therefore, represent statistically secured occurence frequencies for damage caused by accidents. Furthermore, incorrect values for the height of mixing layers used in the German Risk Study were found. (RF) [de

Student Drop-Out from German Higher Education Institutions

Science.gov (United States)

Heublein, Ulrich

2014-01-01

28% of students of any one year currently give up their studies in bachelor degree programmes at German higher education institutions. Drop-out is to be understood as the definite termination in the higher education system without obtaining an academic degree. The drop-out rate is thereby calculated with the help of statistical estimation…

Teaching German-Americana

Science.gov (United States)

Tolzmann, Don Heinrich

1976-01-01

A university course entitled "The German-Americans" attempted to study and evaluate German culture in the U. S. Lecture topics and term paper theses are listed and a selected annotated bibliography of German-American culture is included. (CHK)

Measuring negative attitudes towards overweight and obesity in the German population - psychometric properties and reference values for the German short version of the Fat Phobia Scale (FPS).

Science.gov (United States)

Stein, Janine; Luppa, Melanie; Ruzanska, Ulrike; Sikorski, Claudia; König, Hans-Helmut; Riedel-Heller, Steffi G

2014-01-01

Obesity is one of the leading public health problems worldwide. Obese individuals are often stigmatized and the psychosocial consequences of overweight and obesity are the subject of current research. To detect stigmatizing attitudes towards obese people, the Fat Phobia Scale (FPS) was developed in the USA in the early nineties. In addition, the 14-item short form of the FPS was constructed. The FPS belongs to the most commonly used instruments for measuring negative attitudes towards obese people because of its good psychometric properties. For the recently developed German short form of the FPS, however, the comprehensive investigation of the psychometric properties and the determination of reference values are still pending. Thus, the main objectives of this study were the evaluation of the psychometric quality of the scale as well as the calculation of reference values. The study was based on a representative survey in the German general population. A sample of 1,657 subjects (18-94 years) was assessed via structured telephone interviews including the 14-item German version of the FPS. Descriptive statistics and inference-statistical analyses were conducted. Reference values in terms of percentage ranks were calculated. Substantial evidence for the reliability and validity of the German short version of the FPS was found. This study, for the first time in Germany, provides age-specific reference values for the German short form of the FPS allowing the interpretation of individual test scores. Facing the far-reaching consequences of experienced stigmatization of obese individuals, these study results provide an important basis for further studies aiming at the investigation of negative attitudes towards overweight and obesity.

Robust statistical methods for significance evaluation and applications in cancer driver detection and biomarker discovery

DEFF Research Database (Denmark)

Madsen, Tobias

2017-01-01

In the present thesis I develop, implement and apply statistical methods for detecting genomic elements implicated in cancer development and progression. This is done in two separate bodies of work. The first uses the somatic mutation burden to distinguish cancer driver mutations from passenger m...

Current cancer research. Reports from the German Cancer Research Center 1998

International Nuclear Information System (INIS)

1998-01-01

Topics from the Contents: The Fight against Cancer in Germany - A Critical Review. Conditions and Structures in Research. Familial Breast Cancer - A Critical Assessment. Research without Animal Experiments. Cancer Prevention. New Approaches for Tumor Therapy. Genes, Chromosomes and Cancer. Therapy of Brain Tumors with Laser Neurosurgery. The Genome Project. (orig.) [de

[Validation of the German Version of Tinnitus Functional Index (TFI)].

Science.gov (United States)

Brüggemann, Petra; Szczepek, Agnieszka J; Kleinjung, Tobias; Ojo, Michael; Mazurek, Birgit

2017-09-01

Tinnitus belongs to seriously debilitating auditory conditions and is often complicated by comorbidities such as insomnia, difficulties with concentration, depression, frustration and irritability. To facilitate the grading of symptoms and the effects of therapeutic strategies, we validated a German-version Tinnitus Functional Index (TFI) in 229 subjects suffering from chronic tinnitus. Outcome validity was assessed using the Tinnitus Questionnaire (TQ, German adaptation by Goebel u. Hiller [1998]). Construct validity was assessed using the "Hamburger Allgemeine Depressionsskala" (HADS). The German TFI featured excellent internal consistency (total score Cronbach's α=0.93). Factor analysis disclosed eight TFI subscales as proposed earlier by Meikle et al. [2012]. Intercorrelations were strong both between the TFI and the TQ (r=0.83), and between the TFI and the HADS (depression r=0.49, anxiety r=0.51). The German-version TFI qualifies as a rapid and statistically robust tool for grading the impact of tinnitus on daily living and for the measurements of therapeutic effects. Regarding depressive symptomatology, sensitivity of the TFI was comparable to that of the TQ. © Georg Thieme Verlag KG Stuttgart · New York.

Becoming German: Integration, Citizenship and Territorialization of Germanness

DEFF Research Database (Denmark)

Fogelman, Tatiana

2017-01-01

understandings of integration and Germanness, this paper highlights the neglected aspect of the ascendance of Integrationspolitik since the turn of the century: namely how it superseded previous regime of completely bifurcated migration policy for "foreigners" on the one hand, and so-called "settlers" of German......, seen ever more as residing within its state territory rather than some diffuse cultural-linguistic space. Moving our understanding of Germanness beyond the "ethnic nationhood model" (Faist 2008), I argue thus that, in conjunction with the new citizenship law, the emergence of Integrationspolitik...

Computer-Based Readability Testing of Information Booklets for German Cancer Patients.

Science.gov (United States)

Keinki, Christian; Zowalla, Richard; Pobiruchin, Monika; Huebner, Jutta; Wiesner, Martin

2018-04-12

Understandable health information is essential for treatment adherence and improved health outcomes. For readability testing, several instruments analyze the complexity of sentence structures, e.g., Flesch-Reading Ease (FRE) or Vienna-Formula (WSTF). Moreover, the vocabulary is of high relevance for readers. The aim of this study is to investigate the agreement of sentence structure and vocabulary-based (SVM) instruments. A total of 52 freely available German patient information booklets on cancer were collected from the Internet. The mean understandability level L was computed for 51 booklets. The resulting values of FRE, WSTF, and SVM were assessed pairwise for agreement with Bland-Altman plots and two-sided, paired t tests. For the pairwise comparison, the mean L values are L FRE  = 6.81, L WSTF  = 7.39, L SVM  = 5.09. The sentence structure-based metrics gave significantly different scores (P < 0.001) for all assessed booklets, confirmed by the Bland-Altman analysis. The study findings suggest that vocabulary-based instruments cannot be interchanged with FRE/WSTF. However, both analytical aspects should be considered and checked by authors to linguistically refine texts with respect to the individual target group. Authors of health information can be supported by automated readability analysis. Health professionals can benefit by direct booklet comparisons allowing for time-effective selection of suitable booklets for patients.

Measuring Negative Attitudes towards Overweight and Obesity in the German Population – Psychometric Properties and Reference Values for the German Short Version of the Fat Phobia Scale (FPS)

Science.gov (United States)

Stein, Janine; Luppa, Melanie; Ruzanska, Ulrike; Sikorski, Claudia; König, Hans-Helmut; Riedel-Heller, Steffi G.

2014-01-01

Objective Obesity is one of the leading public health problems worldwide. Obese individuals are often stigmatized and the psychosocial consequences of overweight and obesity are the subject of current research. To detect stigmatizing attitudes towards obese people, the Fat Phobia Scale (FPS) was developed in the USA in the early nineties. In addition, the 14-item short form of the FPS was constructed. The FPS belongs to the most commonly used instruments for measuring negative attitudes towards obese people because of its good psychometric properties. For the recently developed German short form of the FPS, however, the comprehensive investigation of the psychometric properties and the determination of reference values are still pending. Thus, the main objectives of this study were the evaluation of the psychometric quality of the scale as well as the calculation of reference values. Methods The study was based on a representative survey in the German general population. A sample of 1,657 subjects (18–94 years) was assessed via structured telephone interviews including the 14-item German version of the FPS. Descriptive statistics and inference-statistical analyses were conducted. Reference values in terms of percentage ranks were calculated. Results Substantial evidence for the reliability and validity of the German short version of the FPS was found. This study, for the first time in Germany, provides age-specific reference values for the German short form of the FPS allowing the interpretation of individual test scores. Conclusion Facing the far-reaching consequences of experienced stigmatization of obese individuals, these study results provide an important basis for further studies aiming at the investigation of negative attitudes towards overweight and obesity. PMID:25474195

Computational statistics and biometry: which discipline drives which?

Directory of Open Access Journals (Sweden)

Edler, Lutz

2005-06-01

Full Text Available A biometrician's work is defined through the biological or medical problem and the mathematical and statistical methods needed for its solution. This requires in most instances statistical data analysis and the use of methods of computational statistics. At first, it seems quite obvious that the computational needs of the biometric problem determine what has to be developed by the discipline of computational statistics. However, viewing the development of biometry and computational statistics in Germany for the past decades in more details reveals an interesting interaction between the activities of the German Region of the International Biometric Society and groups engaged in computational statistics within Germany. Exact methods of statistical inference and permutation tests, simulations and the use of the Bootstrap, and interactive graphical statistical methods are examples of this fruitful reciprocal benefit. This contribution examines therefore relationships between the historical development of biometry and computational statistics in Germany using as sources of information contributions to the scientific literature, presentations and sessions at scientific conferences on biometry and on computational statistics which influenced the development of both disciplines and exhibits a reciprocal dependency. The annual workshops organized on the Reisensburg now for more than 30 years are recognized as an outstanding factor of this interrelationship. This work aims at the definition of the present status of computational statistics in the German Region of the International Biometric Society and intends to guide and to foster the discussion of the future development of this discipline among biometricians.

A German catastrophe? German historians and the Allied bombings, 1945-2010

NARCIS (Netherlands)

von Benda-Beckmann, B.R.

2010-01-01

As one of the major symbols of German suffering, the Allied bombing war left a strong imprint on German society. To a much wider extent than is often claimed, the Allied bombings became part of German debates on the Second World War. In both the GDR as well as the Federal Republic before and after

[The boycott against German scientists and the German language after World War I].

Science.gov (United States)

Reinbothe, R

2013-12-01

After the First World War, the Allied academies of sciences staged a boycott against German scientists and the German language. The objective of the boycott was to prevent the re-establishment of the prewar dominance of German scientists, the German language and German publications in the area of international scientific cooperation. Therefore the Allies excluded German scientists and the German language from international associations, congresses and publications, while they created new international scientific organizations under their leadership. Medical associations and congresses were also affected, e. g. congresses on surgery, ophthalmology and tuberculosis. Allied physicians replaced the "International Anti-Tuberculosis Association" founded in Berlin in 1902 with the "Union Internationale contre la Tuberculose"/"International Union against Tuberculosis", founded in Paris in 1920. Only French and English were used as the official languages of the new scientific organizations, just as in the League of Nations. The boycott was based on the fact that the German scientists had denied German war guilt and war crimes and glorified German militarism in a manifesto "To The Civilized World!" in 1914. The boycott first started in 1919 and had to be abolished in 1926, when Germany became a member of the League of Nations. Many German and foreign physicians as well as other scientists protested against the boycott. Some German scientists and institutions even staged a counter-boycott impeding the resumption of international collaboration. The boycott entailed an enduring decline of German as an international scientific language. After the Second World War scientists of the victorious Western Powers implemented a complete reorganization of the international scientific arena, based on the same organizational structures and language restrictions they had built up in 1919/1920. At the same time scientists from the U.S.A. staged an active language and publication policy, in

Intestinal parasites in First World War German soldiers from "Kilianstollen", Carspach, France.

Science.gov (United States)

Le Bailly, Matthieu; Landolt, Michaël; Mauchamp, Leslie; Dufour, Benjamin

2014-01-01

Paleoparasitological investigations revealed the presence of intestinal helminths in samples taken from the abdominal cavities of two German soldiers, recovered in the First World War site named "Kilianstollen" in Carspach, France. Eggs from roundworm, whipworm, tapeworm and capillariids were identified. The morphological and morphometrical comparison, followed by statistical analyses, showed that the Carspach capillariid eggs are similar to rodent parasites. Poor sanitary conditions in the trenches, the lack of knowledge of parasites, and the widespread presence of commensal animals, can explain the occurrence of such parasites in human intestines. This study is the second dealing with 20th century human samples. It confirms the presence of intestinal worms in First World War German soldiers. In this case study, the application of statistics to precise measurements facilitated the diagnosis of ancient helminth eggs and completed the microscopic approach.

"We call it Springbok-German!": language contact in the German communities in South Africa.

OpenAIRE

Franke, Katharina

2017-01-01

Varieties of German are spoken all over the world, some of which have been maintained for prolonged periods of time. As a result, these transplanted varieties often show traces of the ongoing language contact as specific to their particular context. This thesis explores one such transplanted German language variety – Springbok- German – as spoken by a small subset of German Lutherans in South Africa. Specifically, this study takes as its focus eight rural German communities acr...

Cancer statistics for African Americans, 2016: Progress and opportunities in reducing racial disparities.

Science.gov (United States)

DeSantis, Carol E; Siegel, Rebecca L; Sauer, Ann Goding; Miller, Kimberly D; Fedewa, Stacey A; Alcaraz, Kassandra I; Jemal, Ahmedin

2016-07-01

In this article, the American Cancer Society provides the estimated number of new cancer cases and deaths for blacks in the United States and the most recent data on cancer incidence, mortality, survival, screening, and risk factors for cancer. Incidence data are from the National Cancer Institute, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries, and mortality data are from the National Center for Health Statistics. Approximately 189,910 new cases of cancer and 69,410 cancer deaths will occur among blacks in 2016. Although blacks continue to have higher cancer death rates than whites, the disparity has narrowed for all cancers combined in men and women and for lung and prostate cancers in men. In contrast, the racial gap in death rates has widened for breast cancer in women and remained level for colorectal cancer in men. The reduction in overall cancer death rates since the early 1990s translates to the avoidance of more than 300,000 deaths among blacks. In men, incidence rates from 2003 to 2012 decreased for all cancers combined (by 2.0% per year) as well as for the top 3 cancer sites (prostate, lung, and colorectal). In women, overall rates during the corresponding time period remained unchanged, reflecting increasing trends in breast cancer combined with decreasing trends in lung and colorectal cancer rates. Five-year relative survival is lower for blacks than whites for most cancers at each stage of diagnosis. The extent to which these disparities reflect unequal access to health care versus other factors remains an active area of research. Progress in reducing cancer death rates could be accelerated by ensuring equitable access to prevention, early detection, and high-quality treatment. CA Cancer J Clin 2016;66:290-308. © 2016 American Cancer Society. © 2016 American Cancer Society, Inc.

Missing data imputation using statistical and machine learning methods in a real breast cancer problem.

Science.gov (United States)

Jerez, José M; Molina, Ignacio; García-Laencina, Pedro J; Alba, Emilio; Ribelles, Nuria; Martín, Miguel; Franco, Leonardo

2010-10-01

Missing data imputation is an important task in cases where it is crucial to use all available data and not discard records with missing values. This work evaluates the performance of several statistical and machine learning imputation methods that were used to predict recurrence in patients in an extensive real breast cancer data set. Imputation methods based on statistical techniques, e.g., mean, hot-deck and multiple imputation, and machine learning techniques, e.g., multi-layer perceptron (MLP), self-organisation maps (SOM) and k-nearest neighbour (KNN), were applied to data collected through the "El Álamo-I" project, and the results were then compared to those obtained from the listwise deletion (LD) imputation method. The database includes demographic, therapeutic and recurrence-survival information from 3679 women with operable invasive breast cancer diagnosed in 32 different hospitals belonging to the Spanish Breast Cancer Research Group (GEICAM). The accuracies of predictions on early cancer relapse were measured using artificial neural networks (ANNs), in which different ANNs were estimated using the data sets with imputed missing values. The imputation methods based on machine learning algorithms outperformed imputation statistical methods in the prediction of patient outcome. Friedman's test revealed a significant difference (p=0.0091) in the observed area under the ROC curve (AUC) values, and the pairwise comparison test showed that the AUCs for MLP, KNN and SOM were significantly higher (p=0.0053, p=0.0048 and p=0.0071, respectively) than the AUC from the LD-based prognosis model. The methods based on machine learning techniques were the most suited for the imputation of missing values and led to a significant enhancement of prognosis accuracy compared to imputation methods based on statistical procedures. Copyright © 2010 Elsevier B.V. All rights reserved.

Inter-rater reliability of the German version of the Nurses' Global Assessment of Suicide Risk scale.

Science.gov (United States)

Kozel, Bernd; Grieser, Manuela; Abderhalden, Christoph; Cutcliffe, John R

2016-10-01

In comparison to the general population, the suicide rates of psychiatric inpatient populations in Germany and Switzerland are very high. An important preventive contribution to the lowering of the suicide rates in mental health care is to ensure that the risk of suicide of psychiatric inpatients is assessed as accurately as possible. While risk-assessment instruments can serve an important function in determining such risk, very few have been translated to German. Therefore, in the present study, we reported on the German version of Nurses' Global Assessment of Suicide Risk (NGASR) scale. After translating the original instrument into German and pretesting the German version, we tested the inter-rater reliability of the instrument. Twelve video case studies were evaluated by 13 raters with the NGASR scale in a 'laboratory' trial. In each case, the observer's agreement was calculated for the single items, the overall scale, the risk levels, and the sum scores. The statistical data analysis was conducted with kappa and AC1 statistics for dichotomous (items, scale) scales. A high-to-very high observers' agreement (AC1: 0.62-1.00, kappa: 0.00-1.00) was determined for 16 items of the German version of the NGASR scale. We conclude that the German version of the NGASR scale is a reliable instrument for evaluating risk factors for suicide. A reliable application in the clinical practise appears to be enhanced by training in the use of the instrument and the right implementation instructions. © 2016 Australian College of Mental Health Nurses Inc.

German nuclear fuel exports and imports 1991

International Nuclear Information System (INIS)

Anon.

1993-01-01

The statistics compiled by the German Federal Office for Trade and Industry (Bundesamt fuer Wirtschaft) for the Federal Ministry for the Environment, Conservation of Nature, and Reactor Safety of imports and exports of nuclear fuels and source materials in 1991 show a major drop by 33.8% in imports and a pronounced rise by 191.5% in exports, compared to the levels in the previous year. Source material for the purposes of these statistics refers only to uranium concentrate. Quantitatively, the biggest import items are source materials, depleted uranium, and uranium enriched up to 3%. Exports of unirradiated material quantitatively comprise mainly depleted uranium, source material, and uranium enriched up to 10%. (orig.) [de

Stopping the greenhouse effect - recommendations submitted by the Bundestag Enquete Commission. - Why nuclear energy cannot solve the global-warming problem - on the urgency of a low-risk, efficient future energy economy. - The latest cancer statistics of the Hiroshima/Nagasaki A-bomb survivors - a higher radiation risk at dose rates below 50cGy (rad) - consequences for radiation protection

International Nuclear Information System (INIS)

Bach, W.; Kohler, S.; Koehnlein, W.

1991-01-01

The report compiles three contributions two of which discuss the issues of global warming, trace gases and ozone depletion. The measures proposed by a German enquete commision to stop the greenhouse effect, i.e. utilization of renewable energy sources, nuclear phaseout because nuclear power is not supposed to solve the global-warming problem, are described. The third contribution gives the latest cancer statistics of the Hiroshima/Nagasaki a-bomb survivors while taking into account the higher radiation risk due to low dose rates. (DG) [de

A multi-scale and model approach to estimate future tidal high water statistics in the southern German Bright

Science.gov (United States)

Hein, H.; Mai, S.; Mayer, B.; Pohlmann, T.; Barjenbruch, U.

2012-04-01

The interactions of tides, external surges, storm surges and waves with an additional role of the coastal bathymetry define the probability of extreme water levels at the coast. Probabilistic analysis and also process based numerical models allow the estimation of future states. From the physical point of view both, deterministic processes and stochastic residuals are the fundamentals of high water statistics. This study uses a so called model chain to reproduce historic statistics of tidal high water levels (Thw) as well as the prediction of future statistics high water levels. The results of the numerical models are post-processed by a stochastic analysis. Recent studies show, that for future extrapolation of extreme Thw nonstationary parametric approaches are required. With the presented methods a better prediction of time depended parameter sets seems possible. The investigation region of this study is the southern German Bright. The model-chain is the representation of a downscaling process, which starts with an emissions scenario. Regional atmospheric and ocean models refine the results of global climate models. The concept of downscaling was chosen to resolve coastal topography sufficiently. The North Sea and estuaries are modeled with the three-dimensional model HAMburg Shelf Ocean Model. The running time includes 150 years (1950 - 2100). Results of four different hindcast runs and also of one future prediction run are validated. Based on multi-scale analysis and the theory of entropy we analyze whether any significant periodicities are represented numerically. Results show that also hindcasting the climate of Thw with a model chain for the last 60 years is a challenging task. For example, an additional modeling activity must be the inclusion of tides into regional climate ocean models. It is found that the statistics of climate variables derived from model results differs from the statistics derived from measurements. E.g. there are considerable shifts in

Statistical methods for site-specific analysis of cancer among the A-bomb survivors

International Nuclear Information System (INIS)

Pierce, D.A.; Preston, D.L.

1992-01-01

Statistical methods are presented for joint, or simultaneous, analysis of the risks of several types of cancer for the A-bomb survivors. Previous analyses have been made either for all cancers except leukemia together, or have been done separately by cancer type. Either of these approaches has serious limitations, and the aim of joint analysis is to overcome these, while taking advantage of the strengths of each. The primary advantage of joint analysis is that models for risks of various cancer types can have some parameters in common, and others which are type-specific. This serves to overcome difficulties due to the limited data on specific cancer types. It also provides for significant tests comparing both type-specific risks and type-specific effects of modifying factors such as sex and age. These methods are exemplified here by joint analysis of three classes of cancer considered by the BEIR-V committee: (i) respiratory, (ii) digestive, and (iii) other cancers, excluding leukemia and breast cancer. The primary aim is to illustrate the general advantages of joint analyses, but in addition some comparison is made between the results of such joint analyses and the conclusions drawn by BEIR-V committee from separate analyses. (author)

Word order in the Germanic languages

DEFF Research Database (Denmark)

Holmberg, Anders; Rijkhoff, Jan

1998-01-01

The Germanic branch of Indo-European consists of three main groups (Ruhlen 1987: 327):- East Germanic: Gothic, Vandalic, Burgundian (all extinct);- North Germanic (or: Scandinavian): Runic (extinct), Danish, Swedish, Norwegian, Icelandic, Faroese;- West Germanic: German, Yiddish, Luxembourgeois, ...

Franco-German initiative for Chernobylsk health project

International Nuclear Information System (INIS)

2006-01-01

The works led within the framework of the French-German initiative ( I.F.A.) on the health of the populations exposed to the ionizing radiations concentrated on the main useful indicators of health for the study of the excess incidence of cancers after a relatively long latency period. No net difference of the tendencies of leukaemia incidence was revealing between exposed regions and not exposed regions of Ukraine, Belarus and Russia. As regards solid tumors, the rates of incidence presented the same tendencies of increase in the course of time whatever are the studied regions. On the other hand, the works showed a net increase of the rate of incidence of the thyroid cancers in the exposed regions, notably at the aged persons of less than ten years at the time of the accident. In Belarus, the national register of cancers allowed to bring to light a very high number of thyroid cancers, from the beginning 1990 at the children of less than 15 years and net increase of these cancers, since 1998, in the slice of 15/29 the years. So for this exposed population, the risk of thyroid cancer continues to express itself 20 years after the accident. Besides, no tangible difference from the point of view of the tendencies between exposed and not exposed regions was revealing for the congenital malformations. (N.C.)

Population-based statistical inference for temporal sequence of somatic mutations in cancer genomes.

Science.gov (United States)

Rhee, Je-Keun; Kim, Tae-Min

2018-04-20

It is well recognized that accumulation of somatic mutations in cancer genomes plays a role in carcinogenesis; however, the temporal sequence and evolutionary relationship of somatic mutations remain largely unknown. In this study, we built a population-based statistical framework to infer the temporal sequence of acquisition of somatic mutations. Using the model, we analyzed the mutation profiles of 1954 tumor specimens across eight tumor types. As a result, we identified tumor type-specific directed networks composed of 2-15 cancer-related genes (nodes) and their mutational orders (edges). The most common ancestors identified in pairwise comparison of somatic mutations were TP53 mutations in breast, head/neck, and lung cancers. The known relationship of KRAS to TP53 mutations in colorectal cancers was identified, as well as potential ancestors of TP53 mutation such as NOTCH1, EGFR, and PTEN mutations in head/neck, lung and endometrial cancers, respectively. We also identified apoptosis-related genes enriched with ancestor mutations in lung cancers and a relationship between APC hotspot mutations and TP53 mutations in colorectal cancers. While evolutionary analysis of cancers has focused on clonal versus subclonal mutations identified in individual genomes, our analysis aims to further discriminate ancestor versus descendant mutations in population-scale mutation profiles that may help select cancer drivers with clinical relevance.

Analytic advanced development in the German Risk Study on Nuclear Power Plants

International Nuclear Information System (INIS)

1984-01-01

The study carried out by the Ecological Institute (Oeko-Institut) deals with the difficulties encountered with the decision-making models and statistical models and methods of the German Risk Study on Nuclear Power Plants for the determination of care meltdown frequency and for the estimation of the behaviour of components in the event of a failure. Related deficiencies of the German Risk Study and the absence of completeness and lading representiveness of the course and causes of incidents considered are pointed out. The accident consequences model and the climatological-meteorological data base are considered non-representative. (RF) [de

Neuroendocrine Tumor: Statistics

Science.gov (United States)

... Tumor > Neuroendocrine Tumor: Statistics Request Permissions Neuroendocrine Tumor: Statistics Approved by the Cancer.Net Editorial Board , 01/ ... the body. It is important to remember that statistics on the survival rates for people with a ...

Statistical approaches for evaluating body composition markers in clinical cancer research.

Science.gov (United States)

Bayar, Mohamed Amine; Antoun, Sami; Lanoy, Emilie

2017-04-01

The term 'morphomics' stands for the markers of body composition in muscle and adipose tissues. in recent years, as part of clinical cancer research, several associations between morphomics and outcome or toxicity were found in different treatment settings leading to a growing interest. we aim to review statistical approaches used to evaluate these markers and suggest practical statistical recommendations. Area covered: We identified statistical methods used recently to take into account properties of morphomics measurements. We also reviewed adjustment methods on major confounding factors such as gender and approaches to model morphomic data, especially mixed models for repeated measures. Finally, we focused on methods for determining a cut-off for a morphomic marker that could be used in clinical practice and how to assess its robustness. Expert commentary: From our review, we proposed 13 key points to strengthen analyses and reporting of clinical research assessing associations between morphomics and outcome or toxicity.

Explanatory models of addictive behaviour among native German, Russian-German, and Turkish youth.

Science.gov (United States)

Penka, S; Heimann, H; Heinz, A; Schouler-Ocak, M

2008-01-01

In Germany, the public system of addiction treatment is used less by migrants with addictive disorders than by their non-migrant counterparts. To date, the literature has focused primarily on language, sociocultural factors, and residence status when discussing access barriers to this part of the health care system. However, little attention has been paid to cultural differences in explanatory models of addictive behaviour. This is surprising when we consider the important role played by popular knowledge in a population's perceptions of and responses to illnesses, including their causes, symptoms, and treatment. In the present study, we examined explanatory models of addictive behaviour and of mental disorders in 124 native German und Russian-German youth and compared these models to those observed in an earlier study of 144 German and Turkish youth. We employed the free listing technique German and to compile the terms that participating subjects used to describe addictive behaviour. Subsequently, we examined how a subset of our study population assigned these terms to the respective disorders by means of the pile sort method. Although the explanatory models used by the German and Russian-German youth in our study were surprisingly similar, those employed by Turkish youth did not make any fundamental distinction between illegal and legal drugs (e.g. alcohol and nicotine). German and Russian-German youth regarded eating disorders as "embarrassing" or "disgraceful", but Turkish youth did not. Unlike our German and Russian-German subjects, the Turkish youth did not classify eating disorders as being addictive in nature. Moreover, medical concepts crucial to a proper understanding of dependence disorders (e.g. the term "physical dependence") were characterised by almost half of our Turkish subjects as useless in describing addictions. These findings show that it is impossible to translate medical or everyday concepts of disease and treatment properly into a different

Features of Moral Foundations in Mongol, German and Russian Adolescents

Directory of Open Access Journals (Sweden)

Sychev O.A.,

2016-04-01

Full Text Available The difference in moral foundations between adults living in Western or Eastern countries is well-known, but there is lack of evidence about such difference in adolescence. We tested the hypothesis about cultural differences of moral foundations in Mongolian, Russian and German adolescents. As the methodology of the study we used Moral Foundations Theory describing five basic dimensions of moral domain including Harm/Care, Fair- ness/Reciprocity, Ingroup/Loyalty, Authority/Respect, and Purity/Sanctity. The sample comprised 446 Mon- golian, 450 Russian and 117 German adolescents at the age of 12…16 years old. We used three versions of Moral Foundations Questionnaire in different languages. The results of statistical analysis showed that general analy- sis, based on relations between scales, was acceptable. The replication of factor structure was low. It was revealed that Mongolian adolescents had most conservative moral foundations. Moral foundations of Russian adolescents from Altai Republic were quite close to Mongolian ones, while German adolescents showed much more «progressive» moral foundations which were typical for western societies.

Intercomparison of four regional climate models for the German State of Saxonia

Science.gov (United States)

Kreienkamp, F.; Spekat, A.; Enke, W.

2009-09-01

Results from four regional climate models which focus on Central Europe are presented: CCLM, the climate version of the German Weather Service's Local Model - REMO, the regional dynamic model from the Max Planck Institute for Meteorology in Hamburg - STAR, the statistical model developed at the PIK Potsdam Institute and WETTREG, the statistic-dynamic model developed by the company CEC Potsdam. For the area of the German State of Saxonia a host of properties and indicators were analyzed aiming to show the models' abilities to reconstruct the current climate and compare climate model scenarios. These include a group of thermal indicators, such as the number of ice, frost, summer and hot days, the number of tropical nights; then there are hydrometeorological indicators such as the exceedance of low and high precipitation thresholds; humidity, cloudiness and wind indicators complement the array. A selection of them showing similarities and differences of the models investigated will be presented.

Quality assurance in X-ray mammography. Comparison of proposed EUREF guidelines with relevant German regulations

International Nuclear Information System (INIS)

Zaers, J.; Brix, G.; Woudenberg, S. van

1997-01-01

The Program 'Europe against Cancer' published the 2nd edition of quality assurance guidelines for breast cancer screening in June 1996. For the enforcement of these guidelines, a European network of reference centres (EUREF) is being established. Although the EUREF protocol contains guidelines for all disciplines involved in breast cancer screening, this article concentrates on the physical and technical aspect. The comparison with the German regulations (DIN Norms) demonstrates the high requirements requested by the EUREF guidelines with its tighter limits and more extensive and more frequent tests. (orig.) [de

DEMorphy, German Language Morphological Analyzer

OpenAIRE

Altinok, Duygu

2018-01-01

DEMorphy is a morphological analyzer for German. It is built onto large, compactified lexicons from German Morphological Dictionary. A guesser based on German declension suffixed is also provided. For German, we provided a state-of-art morphological analyzer. DEMorphy is implemented in Python with ease of usability and accompanying documentation. The package is suitable for both academic and commercial purposes wit a permissive licence.

Health Information in German (Deutsch)

Science.gov (United States)

... Tools You Are Here: Home → Multiple Languages → German (Deutsch) URL of this page: https://medlineplus.gov/languages/german.html Health Information in German (Deutsch) To use the sharing features on this page, ...

DDR-Landeskundliches im Deutschunterricht (East German Culture in the German Lesson).

Science.gov (United States)

Wazel, Gerhard

1988-01-01

Demonstrates with concrete examples from the texts of a German class for advanced learners how aspects of East German culture can be realized in vocabulary, in lectures, and in the development of listening comprehension and speaking skills. Texts are appended. (DJD)

Validation of the German version of the late adolescence and young adulthood survivorship-related quality of life measure (LAYA-SRQL).

Science.gov (United States)

Richter, Diana; Mehnert, Anja; Schepper, Florian; Leuteritz, Katja; Park, Crystal; Ernst, Jochen

2018-01-04

Cancer has adverse effects on patient's quality of life. As such, measuring quality of life (QoL) has become an integral part of psycho-oncological health care. Because adolescent and young adult patients have different needs in contrast to children and older cancer patients, instruments for adequately measuring QoL of cancer survivors in this age range are essential. As there is not a corresponding instrument in Germany, we aimed to validate the German version of the Late Adolescence and Young Adulthood Survivorship-Related Quality of Life Measure (LAYA-SRQL), a 30-item questionnaire covering 10 dimensions related to QoL. The LAYA-SRQL was translated into German following state-of-the-art criteria. We enrolled 234 adolescent and young adult (AYA) cancer patients with different tumour entities aged between 16 and 39 years old. Factorial structure was tested using confirmatory factor analysis. Internal consistency was determined by Cronbach's α. The Short Form Survey quality of life questionnaire (SF-12v2) was used to examine convergent validity. The 10-factor structure of the LAYA-SRQL was confirmed in the German sample, and the model shows high values of fit indicators: χ 2  = 723.32 (df = 360, p  0.70 and total Cronbach's α of 0.93. Convergent validity was demonstrated by high positive correlations between the LAYA-SRQL and the physical (r = 0.45) and mental component (r = 0.65) of the SF-12v2. The German version of the LAYA-SRQL showed good psychometric properties. The instrument proved to be a highly reliable and valid instrument that can be recommended for use in the follow-up care of AYAs and for clinical research.

Statistical study on the self-selection bias in FDG-PET cancer screening by a questionnaire survey

International Nuclear Information System (INIS)

Kita, Tamotsu; Yano, Fuzuki; Watanabe, Sadahiro; Soga, Shigeyoshi; Hama, Yukihiro; Shinmoto, Hiroshi; Kosuda, Shigeru

2008-01-01

A questionnaire survey was performed to investigate the possible presence of self-selection bias in 18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET) cancer screening (PET cancer screening). Responders to the questionnaires survey consisted of 80 healthy persons, who answered whether they undergo PET cancer screening, health consciousness, age, sex, and smoking history. The univariate and multivariate analyses on the four parameters were performed between the responders who were to undergo PET cancer screening and the responders who were not. Statistically significant difference was found in health consciousness between the above-mentioned two groups by both univariate and multivariate analysis with the odds ratio of 2.088. The study indicated that self-selection bias should exist in PET cancer screening. (author)

Thyroid Cancer Statistics | Did You Know?

Science.gov (United States)

Thyroid cancer represents the 8th most common cancer in the United States. Did you know that this cancer, located at the base of the throat in the thyroid gland, is highly treatable and usually curable?

[German influences on Romanian medical terminology].

Science.gov (United States)

Răcilă, R G; Răileanu, Irena; Rusu, V

2008-01-01

The medical terminology plays a key part both in the study of medicine as well as in its practice. Moreover, understanding the medical terms is important not only for the doctor but also for the patients who want to learn more about their condition. For these reasons we believe that the study of medical terminology is one of great interest. The aim of our paper was to evaluate the German linguistic and medical influences on the evolution of the Romanian medical terminology. Since the Romanian-German cultural contacts date back to the 12th century we had reasons to believe that the number of German medical words in Romanian would be significant. To our surprise, the Romanian language has very few German words and even less medical terms of German origin. However, when we searched the list of diseases coined after famous medical personalities, we found out that 26 % of them bore the names of German doctors and scientists. Taken together this proves that the German medical school played an important role on the evolution of Romanian medicine despite the fact that the Romanian vocabulary was slightly influenced by the German language. We explain this fact on the structural differences between the Romanian and German languages, which make it hard for German loans to be integrated in the Romanian lexis. In conclusion we state that the German influence on the Romanian medical terminology is weak despite the important contribution of the German medical school to the development of medical education and healthcare in Romania. Key

[Sample German LAPS.

Science.gov (United States)

Rosenthal, Bianca

Four learning activity packages (LAPS) for use in secondary school German programs contain instructional materials which enable students to improve their basic linguistic skills. The units include: (1) "Grusse," (2) "Ich Heisse...Namen," (3) "Tune into Your Career: Business Correspondence 'Auf Deutch'," and (4) "Understanding German Culture."…

Update of the German Diabetes Risk Score and external validation in the German MONICA/KORA study.

Science.gov (United States)

Mühlenbruch, Kristin; Ludwig, Tonia; Jeppesen, Charlotte; Joost, Hans-Georg; Rathmann, Wolfgang; Meisinger, Christine; Peters, Annette; Boeing, Heiner; Thorand, Barbara; Schulze, Matthias B

2014-06-01

Several published diabetes prediction models include information about family history of diabetes. The aim of this study was to extend the previously developed German Diabetes Risk Score (GDRS) with family history of diabetes and to validate the updated GDRS in the Multinational MONItoring of trends and determinants in CArdiovascular Diseases (MONICA)/German Cooperative Health Research in the Region of Augsburg (KORA) study. We used data from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study for extending the GDRS, including 21,846 participants. Within 5 years of follow-up 492 participants developed diabetes. The definition of family history included information about the father, the mother and/or sibling/s. Model extension was evaluated by discrimination and reclassification. We updated the calculation of the score and absolute risks. External validation was performed in the MONICA/KORA study comprising 11,940 participants with 315 incident cases after 5 years of follow-up. The basic ROC-AUC of 0.856 (95%-CI: 0.842-0.870) was improved by 0.007 (0.003-0.011) when parent and sibling history was included in the GDRS. The net reclassification improvement was 0.110 (0.072-0.149), respectively. For the updated score we demonstrated good calibration across all tenths of risk. In MONICA/KORA, the ROC-AUC was 0.837 (0.819-0.855); regarding calibration we saw slight overestimation of absolute risks. Inclusion of the number of diabetes-affected parents and sibling history improved the prediction of type 2 diabetes. Therefore, we updated the GDRS algorithm accordingly. Validation in another German cohort study showed good discrimination and acceptable calibration for the vast majority of individuals. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Accent, Intelligibility, and the Role of the Listener: Perceptions of English-Accented German by Native German Speakers

Science.gov (United States)

Hayes-Harb, Rachel; Watzinger-Tharp, Johanna

2012-01-01

We explore the relationship between accentedness and intelligibility, and investigate how listeners' beliefs about nonnative speech interact with their accentedness and intelligibility judgments. Native German speakers and native English learners of German produced German sentences, which were presented to 12 native German speakers in accentedness…

German Orientalism

OpenAIRE

Margaret Olin

2011-01-01

Review of: Suzanne L. Marchand, German Orientalism in the Age of Empire: Religion, Race and Scholarship, Cambridge and Washington, D.C.: Cambridge University Press, 2009. This analysis of Suzanne L. Marchand’s German Orientalism in the Age of Empire: Religion, Race and Scholarship reads her contribution in part against the background of Edward Said’s path breaking book Orientalism. Differences lie in her more expansive understanding of the term ‘Oriental’ to include the Far East and her conce...

Symptom Clusters in Advanced Cancer Patients: An Empirical Comparison of Statistical Methods and the Impact on Quality of Life.

Science.gov (United States)

Dong, Skye T; Costa, Daniel S J; Butow, Phyllis N; Lovell, Melanie R; Agar, Meera; Velikova, Galina; Teckle, Paulos; Tong, Allison; Tebbutt, Niall C; Clarke, Stephen J; van der Hoek, Kim; King, Madeleine T; Fayers, Peter M

2016-01-01

Symptom clusters in advanced cancer can influence patient outcomes. There is large heterogeneity in the methods used to identify symptom clusters. To investigate the consistency of symptom cluster composition in advanced cancer patients using different statistical methodologies for all patients across five primary cancer sites, and to examine which clusters predict functional status, a global assessment of health and global quality of life. Principal component analysis and exploratory factor analysis (with different rotation and factor selection methods) and hierarchical cluster analysis (with different linkage and similarity measures) were used on a data set of 1562 advanced cancer patients who completed the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. Four clusters consistently formed for many of the methods and cancer sites: tense-worry-irritable-depressed (emotional cluster), fatigue-pain, nausea-vomiting, and concentration-memory (cognitive cluster). The emotional cluster was a stronger predictor of overall quality of life than the other clusters. Fatigue-pain was a stronger predictor of overall health than the other clusters. The cognitive cluster and fatigue-pain predicted physical functioning, role functioning, and social functioning. The four identified symptom clusters were consistent across statistical methods and cancer types, although there were some noteworthy differences. Statistical derivation of symptom clusters is in need of greater methodological guidance. A psychosocial pathway in the management of symptom clusters may improve quality of life. Biological mechanisms underpinning symptom clusters need to be delineated by future research. A framework for evidence-based screening, assessment, treatment, and follow-up of symptom clusters in advanced cancer is essential. Copyright © 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

How Persistent Are Grammatical Gender Effects? The Case of German and Tamil

Science.gov (United States)

Sedlmeier, Peter; Tipandjan, Arun; Jänchen, Anastasia

2016-01-01

Does the language we speak shape the way we think? The present research concentrated on the impact of grammatical gender on cognition and examined the persistence of the grammatical gender effect by (a) concentrating on German, a three-gendered language, for which previous results have been inconsistent, (b) statistically controlling for common…

Adrenal Gland Tumors: Statistics

Science.gov (United States)

... Gland Tumor: Statistics Request Permissions Adrenal Gland Tumor: Statistics Approved by the Cancer.Net Editorial Board , 03/ ... primary adrenal gland tumor is very uncommon. Exact statistics are not available for this type of tumor ...

Clinical statistics of gynecologic cancers in Japan

Science.gov (United States)

Nagase, Satoru

2017-01-01

Cervical, endometrial, and ovarian cancers, have both high morbidity and mortality among the gynecologic malignant tumors in Japan. The present study was conducted using both the population-based cancer registry and the gynecologic cancer registry to elucidate the characteristics of gynecologic malignant tumors in Japan. Based on nationwide estimates from the population-based cancer registry in Japan, the morbidities and mortality of cervical, endometrial, and ovarian cancers were obtained and used for analysis. Clinicopathologic factors for cervical cancer, endometrial cancer, ovarian cancer, including age, clinical stage, postsurgical stage, histological type, therapeutic strategy, and prognosis were retrieved from the gynecologic cancer registry published by the Japan Society of Obstetrics and Gynecology and used for analysis. The morbidities of cervical, endometrial, and ovarian cancers were 10,908, 13,606, and 9,384 women in 2012, respectively. The prevalence of endometrial cancer has significantly and consistently been increasing and represents the most common gynecologic malignant tumor in Japan. The mortalities of cervical, endometrial, and ovarian cancers were 2.1, 1.3, and 3.2 per 100,000 in 2012, respectively. In 2014, 52.2% of cervical cancer patients were classified as stage I, 22.5% as stage II, 10.2% as stage III, and 11.2% as stage IV. In addition, 71.9% of endometrial cancer patients were classified as stage I, 6.0% as stage II, 13.3% as stage III, and 7.5% as stage IV. Finally, 43.2% of ovarian cancer patients were classified as stage I, 9.1% as stage II, 27.6% as stage III, and 7.2% as stage IV. Twelve-point six percent of ovarian cancer patients received neoadjuvant chemotherapy. PMID:28198168

Crystal chemistry of germanates: Characteristic structural features of Li,Ge-germanates

International Nuclear Information System (INIS)

Ilyushin, G.D.; Dem'yanets, L.N.

2000-01-01

Crystallochemical classification of eleven compounds from the Li-germanate family is suggested. Depending on the set of the primary building units (PBU) (M-octahedra of the composition [GeO 6 ] and T-tetrahedra of the composition [GeO 4 ]) and the type of their 'condensation', these germanates are divided into three crystallochemical groups: framework MT-structures (four phases), condensed MT-structures (two phases), and tetrahedral T-condensed structures (five phases). The structural characteristics of the framework Li,Ge-germanates are considered, i.e., their symmetry, crystallographically independent sets of the primary building units, framework architecture, and the types of chains and layers of the (Ge,O)-radicals

The German Generations and Gender Survey: Some Critical Reflections on the Validity of Fertility Histories

Directory of Open Access Journals (Sweden)

Michaela Kreyenfeld

2013-01-01

Full Text Available This paper validates the fertility histories of the German Generations and Gender Survey (GGS. Focusing on the cohorts 1930-69 of West German women, the total number of children, the parity distribution and the parity progression ratios are compared to external sources. One major result from this validation is that the German GGS understates the fertility for the older cohorts and overstates it for the younger ones. We presume that two mechanisms are responsible for this pattern in the German GGS: On the one hand, children who have left parental home are underreported in the retrospective fertility histories. On the other hand, women with small children are easier to reach by the interviewer. These two mechanisms taken together produce too low numbers of children for the older and too high ones for the younger cohorts. Extending the validation to marital histories has revealed a similar bias. Our general conclusion from this investigation is that the German GGS may not be used for statistical analyses of cohort fertility and marriage trends. For subsequent surveys, we suggest integrating simple control questions in questionnaires with complex retrospective fertility and union histories.

OF ALIENATION, ASSOCIATION, AND ADVENTURE: WHY GERMAN FIGHTERS JOIN ISIL

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Dorle Hellmuth

2016-03-01

Full Text Available This article provides an analysis of German foreign fighters who have left for Syria and Iraq since early 2012 and make up the second largest contingent among Western foreign fighters. It draws on statistical information about German foreign fighters, but also uses case studies in an attempt to shed more detailed light on their motivations and why they became radicalized. Drawing on recently released government data, trial documents, and media reports, the article seeks to contribute to new research on the prevailing mechanisms of Jihadi radicalization. To facilitate this kind of comprehensive analysis, McCauley and Moskalenko’s Friction framework is applied to fourteen prominent German fighters, including Denis Cuspert (who served as medium-level ISIL propaganda official, Philip Bergner and Robert Baum (responsible for ISIL suicide attacks in Iraq and Syria, Kreshnik B. and Harun Pashtoon (among the first returning fighters convicted of ISIL membership and other terrorist activities. The article concludes with a discussion of countermeasures used to prevent foreign fighters from leaving Germany, deradicalize those who have started to embrace violent ideas and/or actions, and deal with returning foreign fighters.

[Pro Familia statistics for 1974].

Science.gov (United States)

1975-09-01

Statistics for 1974 for the West German family planning organization Pro Familia are reported. 56 offices are now operating, and 23,726 clients were seen. Men were seen more frequently than previously. 10,000 telephone calls were also handled. 16-25 year olds were increasingly represented in the clientele, as were unmarried persons of all ages. 1,242 patients were referred to physicians or clinics for clinical diagnosis.

Music to Teach German By.

Science.gov (United States)

Schulte, Leo

1985-01-01

Discusses how music can be intergrated with regular lesson plans to teach German vocabulary, grammar, and history and to give insights into German culture. Also included are sources for basic background information, a list of recordings of the German music, and notes on selecting and presenting it in the language class. (SED)

First German disease management program for breast cancer.

Science.gov (United States)

Rupprecht, Christoph

2005-01-01

The first disease management program contract for breast cancer in Germany was signed in 2002 between the Association of Regional of Physicians in North-Rhine and the statutory health insurance companies in Rhineland. At the heart of this unique breast cancer disease management program is a patient-centered network of health care professionals. The program's main objectives are: (1) to improve the quality of treatment and post-operative care for breast cancer patients, (2) to provide timely information and consultation empowering the patient to participate in decisionmaking, (3) to improve the interface between inpatient and outpatient care, and (4) to increase the number of breast-conserving surgeries.

German radionuclide exports and imports 1990

International Nuclear Information System (INIS)

Anon.

1991-01-01

The statistics compiled by the German Federal Office for Trade and Industry (Bundesamt fuer Wirtschaft) for the Federal Ministry for the Environment, Conservation of Nature, and Reactor Protection of imports and exports of radionuclides, irradiation samples and sealed emitters above 1850 GBq show a slight decline by 11.8%, on the basis of activity, in imports and a somewhat higher rise by 21.6% in exports in 1990. Imports returned to the level of 1988 after having experienced an extraordinary rise in 1989. Exports were slightly better than in the previous year, but still considerably below the average of the past five years. (orig.) [de

Combined experimental and statistical strategy for mass spectrometry based serum protein profiling for diagnosis of breast cancer

DEFF Research Database (Denmark)

Callesen, Anne Kjærgaard; Vach, Werner; Jørgensen, Per E

2008-01-01

it in a well-described breast cancer case-control study. A rigorous sample collection protocol ensured high quality specimen and reduced bias from preanalytical factors. Preoperative serum samples obtained from 48 breast cancer patients and 28 controls were used to generate MALDI MS protein profiles. A total...... and controls. A diagnostic rule based on these 72 mass values was constructed and exhibited a cross-validated sensitivity and specificity of approximately 85% for the detection of breast cancer. With this method, it was possible to distinguish early stage cancers from controls without major loss of sensitivity...... and specificity. We conclude that optimized serum sample handling and mass spectrometry data acquisition strategies in combination with statistical analysis provide a viable platform for serum protein profiling in cancer diagnosis....

Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a german breast group 26/breast international group 03-05 study

DEFF Research Database (Denmark)

von Minckwitz, Gunter; du Bois, Andreas; Schmidt, Marcus

2009-01-01

PURPOSE: Trastuzumab shows clinical activity in human epidermal growth factor receptor 2 (HER-2)-positive early and advanced breast cancer. In the German Breast Group 26/Breast International Group 03-05 trial, we investigated if trastuzumab treatment should be continued beyond progression. METHODS......: Patients with HER-2-positive breast cancer that progresses during treatment with trastuzumab were randomly assigned to receive capecitabine (2,500 mg/m(2) body-surface area on days 1 through 14 [1,250 mg/m(2) semi-daily]) alone or with continuation of trastuzumab (6 mg/kg body weight) in 3-week cycles....... The primary end point was time to progression. RESULTS: We randomly assigned 78 patients to capecitabine and 78 patients to capecitabine plus trastuzumab. Sixty-five events and 38 deaths in the capecitabine group and 62 events and 33 deaths in the capecitabine-plus-trastuzumab group occurred during 15...

How do German bilingual schoolchildren process German prepositions? - A study on language-motor interactions.

Science.gov (United States)

Ahlberg, Daniela Katharina; Bischoff, Heike; Strozyk, Jessica Vanessa; Bryant, Doreen; Kaup, Barbara

2018-01-01

While much support is found for embodied language processing in a first language (L1), evidence for embodiment in second language (L2) processing is rather sparse. In a recent study, we found support for L2 embodiment, but also an influence of L1 on L2 processing in adult learners. In the present study, we compared bilingual schoolchildren who speak German as one of their languages with monolingual German schoolchildren. We presented the German prepositions auf (on), über (above), and unter (under) in a Stroop-like task. Upward or downward responses were made depending on the font colour, resulting in compatible and incompatible trials. We found compatibility effects for all children, but in contrast to the adult sample, there were no processing differences between the children depending on the nature of their other language, suggesting that the processing of German prepositions of bilingual children is embodied in a similar way as in monolingual German children.

Estadísticas en el cáncer de piel Statistics in skin cancer

Directory of Open Access Journals (Sweden)

RE Achenbach

Full Text Available Se establecen puntos de vista diferentes que influyen, al momento de presentar trabajos de estadística en la esfera del cáncer de la piel, especialmente respecto de las denominadas dermatosis precancerosas, al carcinoma espinocelular y cuál es la más frecuente en el ser humano.A different point of view in the sphere of statistics in skin cancer, specially about squamous cell carcinoma, solar keratosis and the so called precancerous dermatosis. The numerous papers about the issue from AB Ackerman, should be known in order of confident statistics numbers.

SEER Statistics | DCCPS/NCI/NIH

Science.gov (United States)

The Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute works to provide information on cancer statistics in an effort to reduce the burden of cancer among the U.S. population.

Robots drive the German radical prostatectomy market: a total population analysis from 2006 to 2013.

Science.gov (United States)

Groeben, C; Koch, R; Baunacke, M; Wirth, M P; Huber, J

2016-12-01

To assess trends in the distribution of patients for radical prostatectomy in Germany from 2006 to 2013 and the impact of robotic surgery on annual caseloads. We hypothesized that the advent of robotics and the establishment of certified prostate cancer centers caused centralization in the German radical prostatectomy market. Using remote data processing we analyzed the nationwide German billing data from 2006 to 2013. We supplemented this database with additional hospital characteristics like the prostate cancer center certification status. Inclusion criteria were a prostate cancer diagnosis combined with radical prostatectomy. Hospitals with certification or a surgical robot in 2009 were defined as 'early' group. Linear covariant-analytic models were applied to describe trends over time. Annual radical prostatectomy numbers declined from 28 374 (2006) to 21 850 (2013). High-volume hospitals (⩾100 cases) decreased from 87 (22.0%) in 2006 to 43 (10.4%) in 2013. Low-volume hospitals (200 cases per year contrary to the overall trend (Pdecentralization of radical prostatectomy in Germany. The driving force for this development might consist in the overall decline of radical prostatectomy numbers. The most important factor for achieving higher caseloads was the presence of a robotic system. In order to optimize outcomes of radical prostatectomy additional health policy measures might be necessary.

Some statistical considerations related to the estimation of cancer risk following exposure to ionizing radiation

International Nuclear Information System (INIS)

Land, C.E.; Pierce, D.A.

1983-01-01

Statistical theory and methodology provide the logical structure for scientific inference about the cancer risk associated with exposure to ionizing radiation. Although much is known about radiation carcinogenesis, the risk associated with low-level exposures is difficult to assess because it is too small to measure directly. Estimation must therefore depend upon mathematical models which relate observed risks at high exposure levels to risks at lower exposure levels. Extrapolated risk estimates obtained using such models are heavily dependent upon assumptions about the shape of the dose-response relationship, the temporal distribution of risk following exposure, and variation of risk according to variables such as age at exposure, sex, and underlying population cancer rates. Expanded statistical models, which make explicit certain assumed relationships between different data sets, can be used to strengthen inferences by incorporating relevant information from diverse sources. They also allow the uncertainties inherent in information from related data sets to be expressed in estimates which partially depend upon that information. To the extent that informed opinion is based upon a valid assessment of scientific data, the larger context of decision theory, which includes statistical theory, provides a logical framework for the incorporation into public policy decisions of the informational content of expert opinion

German translation, cultural adaptation, and validation of the Health Literacy Questionnaire (HLQ).

Science.gov (United States)

Nolte, Sandra; Osborne, Richard H; Dwinger, Sarah; Elsworth, Gerald R; Conrad, Melanie L; Rose, Matthias; Härter, Martin; Dirmaier, Jörg; Zill, Jördis M

2017-01-01

The Health Literacy Questionnaire (HLQ), developed in Australia in 2012 using a 'validity-driven' approach, has been rapidly adopted and is being applied in many countries and languages. It is a multidimensional measure comprising nine distinct domains that may be used for surveys, needs assessment, evaluation and outcomes assessment as well as for informing service improvement and the development of interventions. The aim of this paper is to describe the German translation of the HLQ and to present the results of the validation of the culturally adapted version. The HLQ comprises 44 items, which were translated and culturally adapted to the German context. This study uses data collected from a sample of 1,058 persons with chronic conditions. Statistical analyses include descriptive and confirmatory factor analyses. In one-factor congeneric models, all scales demonstrated good fit after few model adjustments. In a single, highly restrictive nine-factor model (no cross-loadings, no correlated errors) replication of the original English-language version was achieved with fit indices and psychometric properties similar to the original HLQ. Reliability for all scales was excellent, with a Cronbach's Alpha of at least 0.77. High to very high correlations between some HLQ factors were observed, suggesting that higher order factors may be present. Our rigorous development and validation protocol, as well as strict adaptation processes, have generated a remarkable reproduction of the HLQ in German. The results of this validation provide evidence that the HLQ is robust and can be recommended for use in German-speaking populations. German Clinical Trial Registration (DRKS): DRKS00000584. Registered 23 March 2011.

Layers of root nouns in Germanic

DEFF Research Database (Denmark)

Hansen, Bjarne Simmelkjær Sandgaard

2017-01-01

The root-noun declension became productive in early Germanic, containing (I) inherited root nouns, (IIa) original substrate or loan words, and transitions from other declensions in (IIb) Proto-Germanic and (III) North Germanic. As ablaut was abolished, the inherited type would display ablaut grades...

How do German bilingual schoolchildren process German prepositions? – A study on language-motor interactions

Science.gov (United States)

Bischoff, Heike; Strozyk, Jessica Vanessa; Bryant, Doreen; Kaup, Barbara

2018-01-01

While much support is found for embodied language processing in a first language (L1), evidence for embodiment in second language (L2) processing is rather sparse. In a recent study, we found support for L2 embodiment, but also an influence of L1 on L2 processing in adult learners. In the present study, we compared bilingual schoolchildren who speak German as one of their languages with monolingual German schoolchildren. We presented the German prepositions auf (on), über (above), and unter (under) in a Stroop-like task. Upward or downward responses were made depending on the font colour, resulting in compatible and incompatible trials. We found compatibility effects for all children, but in contrast to the adult sample, there were no processing differences between the children depending on the nature of their other language, suggesting that the processing of German prepositions of bilingual children is embodied in a similar way as in monolingual German children. PMID:29538404

Understanding Cancer Prognosis

Medline Plus

Full Text Available ... Understanding Cancer What Is Cancer? Cancer Statistics Cancer Disparities Understanding Cancer What Is Cancer Cancer Statistics Cancer Disparities Causes & Prevention Risk Factors Genetics Cancer Prevention Overview ...

Cross-linguistic vowel variation in trilingual speakers of Saterland Frisian, Low German, and High German.

Science.gov (United States)

Peters, Jörg; Heeringa, Wilbert J; Schoormann, Heike E

2017-08-01

The present study compares the acoustic realization of Saterland Frisian, Low German, and High German vowels by trilingual speakers in the Saterland. The Saterland is a rural municipality in northwestern Germany. It offers the unique opportunity to study trilingualism with languages that differ both by their vowel inventories and by external factors, such as their social status and the autonomy of their speech communities. The objective of the study was to examine whether the trilingual speakers differ in their acoustic realizations of vowel categories shared by the three languages and whether those differences can be interpreted as effects of either the differences in the vowel systems or of external factors. Monophthongs produced in a /hVt/ frame revealed that High German vowels show the most divergent realizations in terms of vowel duration and formant frequencies, whereas Saterland Frisian and Low German vowels show small differences. These findings suggest that vowels of different languages are likely to share the same phonological space when the speech communities largely overlap, as is the case with Saterland Frisian and Low German, but may resist convergence if at least one language is shared with a larger, monolingual speech community, as is the case with High German.

Excessive Profits of German Defense Contractors

Science.gov (United States)

2014-09-01

its business unit Thyssen Krupp Marine Systems, is a German defense contractor. (2) Tognom AG Tognum AG owned the MTU Friedrichshafen GmbH before... Friedrichshafen provided engines for many ships of the German Navy and for German battle tanks, such as the Leopard I and Leopard II. MTU refers to the

Serum 25-hydroxyvitamin d and cancer risk in older adults: results from a large German prospective cohort study.

Science.gov (United States)

Ordóñez-Mena, José M; Schöttker, Ben; Haug, Ulrike; Müller, Heiko; Köhrle, Josef; Schomburg, Lutz; Holleczek, Bernd; Brenner, Hermann

2013-05-01

Several observational studies assessed the relationship between serum 25-hydroxyvitamin D [25(OH)D] concentrations and the risk of cancer but results were inconclusive. We measured 25(OH)D concentrations in a population-based cohort study of 9,949 men and women ages 50 to 74 years in Saarland, Germany. Comprehensively adjusted Cox regression models were applied to estimate HRs and 95% confidence intervals (CI) for the association between season-standardized 25(OH)D concentrations and total and site-specific cancer incidence. Overall, during a median of 8 years of follow-up, 873 subjects developed cancer; the most common being prostate (171), breast (137), lung (136), and colorectal (136) cancer. Low season-standardized 25(OH)D (risk was observed for low 25(OH)D among men, nonobese subjects and subjects reporting low fish consumption and for high 25(OH)D in nonsmokers and nonobese subjects. Accordingly, restricted cubic splines to investigate dose-response relationships curves showed an inverse association of 25(OH)D levels and total cancer risk in men but not in women. 25(OH)D concentrations were significantly associated with overall cancer incidence in subgroups of this large cohort from Germany. No significant association was observed with site-specific cancers but this could be due to a limited statistical power for these endpoints. Further research should clarify whether and to what extent specific risk groups might profit from vitamin D supplementation.

Care of cancer patients at the end of life in a German university hospital: A retrospective observational study from 2014.

Directory of Open Access Journals (Sweden)

Burkhard Dasch

Full Text Available Cancer care including aggressive treatment procedures during the last phase of life in patients with incurable cancer has increasingly come under scrutiny, while integrating specialist palliative care at an early stage is regarded as indication for high quality end-of-life patient care.To describe the demographic and clinical characteristics and the medical care provided at the end of life of cancer patients who died in a German university hospital.Retrospective cross-sectional study on the basis of anonymized hospital data for cancer patients who died in the Munich University Hospital in 2014. Descriptive analysis and multivariate logistic regression analyses for factors influencing the administration of aggressive treatment procedures at the end of life.Overall, 532 cancer patients died. Mean age was 66.8 years, 58.5% were men. 110/532 (20.7% decedents had hematologic malignancies and 422/532 (79.3% a solid tumor. Patients underwent the following medical interventions in the last 7/30 days: chemotherapy (7.7%/38.3%, radiotherapy (2.6%/6.4%, resuscitation (8.5%/10.5%, surgery (15.2%/31.0%, renal replacement therapy (12.0%/16.9%, blood transfusions (21.2%/39.5%, CT scan (33.8%/60.9%. In comparison to patients with solid tumors, patients with hematologic malignancies were more likely to die in intensive care (25.4% vs. 49.1%; p = 0.001, and were also more likely to receive blood transfusions (OR 2.21; 95% CI, 1.36 to 3.58; p = 0.001 and renal replacement therapy (OR 2.65; 95% CI, 1.49 to 4.70; p = 0.001 in the last 7 days of life. Contact with the hospital palliative care team had been initiated in 161/532 patients (30.3%. In 87/161 cases (54.0%, the contact was initiated within the last week of the patient's life.Overambitious treatments are still reality at the end of life in cancer patients in hospital but patients with solid tumors and hematologic malignancies have to be differentiated. More efforts are necessary for the timely inclusion of

Enriching the Curriculum with Pennsylvania German

Science.gov (United States)

Meindl, Joerg

2016-01-01

The German classroom should prepare students for the linguistic diversity of the target culture, including regional varieties and German spoken outside of the D-A-CH region. Because textbooks do not often include materials on regional varieties, this article presents a model to incorporate Pennsylvania German (PG) into the curriculum. The model…

Steam generators. English-German, German-English. Dampferzeuger. Englisch-Deutsch, Deutsch-Englisch

Energy Technology Data Exchange (ETDEWEB)

Junge, H D

1986-01-01

This pocket dictionary contains the most important technical terms relating to steam generators both in English-German and German-English. Part of the terms go with additional definitions or explanations. Furthermore numerous examples are presented to explain the underlying rules for the formation of word combinations. In addition, entries include a number of general terms, as experience shows that suitable equivalents for use in technical texts are often needed precisely by the specialist. (HAG).

More Cancer Types - SEER Cancer Stat Facts

Science.gov (United States)

Cancer Statistical Fact Sheets are summaries of common cancer types developed to provide an overview of frequently-requested cancer statistics including incidence, mortality, survival, stage, prevalence, and lifetime risk.

Translation and validation of the German version of the Bournemouth Questionnaire for Neck Pain

Directory of Open Access Journals (Sweden)

Soklic Marina

2012-01-01

Full Text Available Abstract Background Clinical outcome measures are important tools to monitor patient improvement during treatment as well as to document changes for research purposes. The short-form Bournemouth questionnaire for neck pain patients (BQN was developed from the biopsychosocial model and measures pain, disability, cognitive and affective domains. It has been shown to be a valid and reliable outcome measure in English, French and Dutch and more sensitive to change compared to other questionnaires. The purpose of this study was to translate and validate a German version of the Bournemouth questionnaire for neck pain patients. Methods German translation and back translation into English of the BQN was done independently by four persons and overseen by an expert committee. Face validity of the German BQN was tested on 30 neck pain patients in a single chiropractic practice. Test-retest reliability was evaluated on 31 medical students and chiropractors before and after a lecture. The German BQN was then assessed on 102 first time neck pain patients at two chiropractic practices for internal consistency, external construct validity, external longitudinal construct validity and sensitivity to change compared to the German versions of the Neck Disability Index (NDI and the Neck Pain and Disability Scale (NPAD. Results Face validity testing lead to minor changes to the German BQN. The Intraclass Correlation Coefficient for the test-retest reliability was 0.99. The internal consistency was strong for all 7 items of the BQN with Cronbach α's of .79 and .80 for the pre and post-treatment total scores. External construct validity and external longitudinal construct validity using Pearson's correlation coefficient showed statistically significant correlations for all 7 scales of the BQN with the other questionnaires. The German BQN showed greater responsiveness compared to the other questionnaires for all scales. Conclusions The German BQN is a valid and

[Different explanatory models for addictive behavior in Turkish and German youths in Germany: significance for prevention and treatment].

Science.gov (United States)

Penka, S; Krieg, S; Hunner, Ch; Heinz, A

2003-07-01

Due to cultural and social barriers, immigrants seldom frequent centers for information, counseling, and treatment of addictive disorders. We examine cultural differences in the explanatory models of addictive behavior among Turkish and German youths in Germany with statistical devices that map the concepts associated with problems of addiction. Relevant differences were found between the disorder concepts of Turkish and German youth. German but not Turkish youths classified eating disorders among severe addictive disorders and associated them with embarrassment and shame. Concerning substance abuse, German but not Turkish youths clearly differentiated between illegal drug abuse and the abuse of alcohol and nicotine. Nearly half of all Turkish youths rejected central medical concepts such as "physical dependence" or "reduced control of substance intake" as completely inadequate to characterize problems of addictive behavior. Preventive information programs must consider these differences and use concepts that are accepted and clearly associated with addictive behavior by immigrant populations.

Workers' Participation and the Distribution of Control as Perceived by Members of Ten German Companies.

Science.gov (United States)

Bartolke, Klaus; And Others

1982-01-01

A survey of 601 managers and workers in 10 German manufacturing companies studied the implications of workers' participation for the exercise of control. Statistical analysis of data on control over work environments, production organization, personnel, and finance indicated that, in more participative companies, distribution of control is more…

Unavailability of thymidine kinase does not preclude the use of German comprehensive prognostic index: results of an external validation analysis in early chronic lymphocytic leukemia and comparison with MD Anderson Cancer Center model.

Science.gov (United States)

Molica, Stefano; Giannarelli, Diana; Mirabelli, Rosanna; Levato, Luciano; Russo, Antonio; Linardi, Maria; Gentile, Massimo; Morabito, Fortunato

2016-01-01

A comprehensive prognostic index that includes clinical (i.e., age, sex, ECOG performance status), serum (i.e., ß2-microglobulin, thymidine kinase [TK]), and molecular (i.e., IGVH mutational status, del 17p, del 11q) markers developed by the German CLL Study Group (GCLLSG) was externally validated in a prospective, community-based cohort consisting of 338 patients with early chronic lymphocytic leukemia (CLL) using as endpoint the time to first treatment (TTFT). Because serum TK was not available, a slightly modified version of the model based on seven instead of eight prognostic variables was used. By German index, 62.9% of patients were scored as having low-risk CLL (score 0-2), whereas 37.1% had intermediate-risk CLL (score 3-5). This stratification translated into a significant difference in the TTFT [HR = 4.21; 95% C.I. (2.71-6.53); P reliability [HR = 2.73; 95% C.I. (1.79-4.17); P German score. The c-statistic of the MDACC model was 0.65 (range, 0.53-0.78) a level below that of the German index [0.71 (range, 0.60-0.82)] and below the accepted 0.7 threshold necessary to have value at the individual patient level. Results of this external comparative validation analysis strongly support the German score as the benchmark for comparison of any novel prognostic scheme aimed at evaluating the TTFT in patients with early CLL even when a modified version which does not include TK is utilized. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Silent Film in the German Classroom.

Science.gov (United States)

Caldwell, David

In addition to using films in the German classroom to introduce students to German culture and history, it is important to show and study the film as film. This procedure emphasizes the importance of the film as a part of creative arts in Germany and demands student participation in observation and discussion. Many German silent films are…

Occupational risk factors for skin cancer and the availability of sun protection measures at German outdoor workplaces.

Science.gov (United States)

Ruppert, Linda; Ofenloch, Robert; Surber, Christian; Diepgen, Thomas

2016-08-01

Germany implemented a new occupational disease "squamous cell carcinoma or multiple actinic keratosis due to natural UV radiation (UVR)" into the German ordinance on occupational diseases. Since primary prevention is very important, the aim of this study was to assess the provision of sun protection measures by the employers in vocational school students for outdoor professions. We conducted a cross-sectional study on the availability of sun protection measures at German workplaces and the risk of occupational sunburn by surveying 245 vocational school students working in outdoor occupations. More than 40 % of the students did not receive any sun protection measures by their employer, and 34.5 % of the students got sunburned during work. Working in the shade was a protective factor for occupational sunburn but was merely available for 23.7 % of the outdoor workers. Our study reveals a strong need for effective sun protection measures, including both administrative controls like education and personal protection measures at German outdoor workplaces.

Using a statistical process control chart during the quality assessment of cancer registry data.

Science.gov (United States)

Myles, Zachary M; German, Robert R; Wilson, Reda J; Wu, Manxia

2011-01-01

Statistical process control (SPC) charts may be used to detect acute variations in the data while simultaneously evaluating unforeseen aberrations that may warrant further investigation by the data user. Using cancer stage data captured by the Summary Stage 2000 (SS2000) variable, we sought to present a brief report highlighting the utility of the SPC chart during the quality assessment of cancer registry data. Using a county-level caseload for the diagnosis period of 2001-2004 (n=25,648), we found the overall variation of the SS2000 variable to be in control during diagnosis years of 2001 and 2002, exceeded the lower control limit (LCL) in 2003, and exceeded the upper control limit (UCL) in 2004; in situ/localized stages were in control throughout the diagnosis period, regional stage exceeded UCL in 2004, and distant stage exceeded the LCL in 2001 and the UCL in 2004. Our application of the SPC chart with cancer registry data illustrates that the SPC chart may serve as a readily available and timely tool for identifying areas of concern during the data collection and quality assessment of central cancer registry data.

German Idealism Today

DEFF Research Database (Denmark)

This collection of essays provides an exemplary overwiew of the diversity and relevance of current scholarship on German Idealism. The importance of German Idealism for contemporary philosophy has recieved growing attention and acknowledgment throughout competing fields of contemporary philosophy...... scholarly debates beyond merely antiquarian perspectives. This renaissance has been a major factor of current efforts to bridge the gap between so-called "nalytic" and so-called "continental" philosophy. The volume provides a selection of readings that contributes to systematic treatments of philosophical...

Risk classification and cream skimming on the deregulated German insurance market

OpenAIRE

Beschorner, Patrick F. E.

2003-01-01

In a two-stage model insurance companies first decide upon risk classification and then compete in prices. I show that the observed heterogeneous behavior of similar firms is compatible with rational behavior. On the deregulated German insurance market individual application of classification schemes induces welfare losses due to cream skimming. Classification costs and pricing above marginal cost can be prevented by common industry-wide loss statistics which already exist to a rudimentary ex...

A simple route to synthesize manganese germanate nanorods

International Nuclear Information System (INIS)

Pei, L.Z.; Yang, Y.; Yuan, C.Z.; Duan Taike; Zhang Qianfeng

2011-01-01

Manganese germanate nanorods have been synthesized by a simple route using germanium dioxide and manganese acetate as the source materials. X-ray diffraction observation shows that the nanorods are composed of orthorhombic and monoclinic manganese germanate phases. Scanning electron microscopy and transmission electron microscopy observations display that the manganese germanate nanorods have flat tips with the length of longer than 10 micrometers and diameter of 60-350 nm, respectively. The role of the growth conditions on the formation of the manganese germanate nanorods shows that the proper selection and combination of the growth conditions are the key factor for controlling the formation of the manganese germanate nanorods. The photoluminescence spectrum of the manganese germanate nanorods exhibits four fluorescence emission peaks centered at 422 nm, 472 nm, 487 nm and 530 nm showing the application potential for the optical devices. - Research Highlights: → Manganese germanate nanorods have been synthesized by simple hydrothermal process. → The formation of manganese germanate nanorods can be controlled by growth conditions. → Manganese germanate nanorods exhibit good PL emission ability for optical device.

New German abortion law agreed.

Science.gov (United States)

Karcher, H L

1995-07-15

The German Bundestag has passed a compromise abortion law that makes an abortion performed within the first three months of pregnancy an unlawful but unpunishable act if the woman has sought independent counseling first. Article 218 of the German penal code, which was established in 1871 under Otto von Bismarck, had allowed abortions for certain medical or ethical reasons. After the end of the first world war, the Social Democrats tried to legalize all abortions performed in the first three months of pregnancy, but failed. In 1974, abortion on demand during the first 12 weeks was declared legal and unpunishable under the social liberal coalition government of chancellor Willy Brandt; however, the same year, the German Federal Constitution Court in Karlsruhe ruled the bill was incompatible with article 2 of the constitution, which guarantees the right to life and freedom from bodily harm to everyone, including the unborn. The highest German court also ruled that a pregnant woman had to seek a second opinion from an independent doctor before undergoing an abortion. A new, extended article 218, which included a clause giving social indications, was passed by the Bundestag. When Germany was unified, East Germans agreed to be governed by all West German laws, except article 218. The Bundestag was given 2 years to revise the article; however, in 1993, the Federal Constitution Court rejected a version legalizing abortion in the first 3 months of the pregnancy if the woman sought counsel from an independent physician, and suggested the recent compromise passed by the Bundestag, the lower house of the German parliament. The upper house, the Bundesrat, where the Social Democrats are in the majority, still has to pass it. Under the bill passed by the Bundestag, national health insurance will pay for an abortion if the monthly income of the woman seeking the abortion falls under a certain limit.

Risk of cancer incidence before the age of 15 years after exposure to ionising radiation from computed tomography: results from a German cohort study

Energy Technology Data Exchange (ETDEWEB)

Krille, L. [University Medical Center Mainz, Institute of Medical Biostatistics, Epidemiology and Informatics, Mainz (Germany); International Agency for Research on Cancer, Lyon (France); Dreger, S.; Zeeb, H. [University of Bremen, Leibniz - Institute for Prevention Research and Epidemiology - BIPS, Research Focus Health Sciences Bremen, Bremen (Germany); Schindel, R.; Blettner, M. [University Medical Center Mainz, Institute of Medical Biostatistics, Epidemiology and Informatics, Mainz (Germany); Albrecht, T. [Vivantes, Klinikum Neukoelln, Institut fuer Radiologie und Interventionelle Therapie, Berlin (Germany); Asmussen, M. [Zentralinstitut fuer Bildgebende Diagnostik, Staedtisches Klinikum Karlsruhe, Karlsruhe (Germany); Barkhausen, J. [Universitaetsklinikum Schleswig Holstein, Klinik fuer Radiologie und Nuklearmedizin, Campus Luebeck, Luebeck (Germany); Berthold, J.D. [Medizinische Hochschule Hannover, Institut fuer Diagnostische und Interventionelle Radiologie, Hannover (Germany); Chavan, A. [Klinikum Oldenburg GmbH, Institut fuer Diagnostische and Interventionelle Radiologie, Oldenburg (Germany); Claussen, C. [Universitaetsklinikum Tuebingen, Abt. fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Forsting, M. [Universitaetsklinikum Essen, Institut fuer Diagnostische und Interventionelle Radiologie und Neuroradiologie, Essen (Germany); Gianicolo, E.A.L. [University Medical Center Mainz, Institute of Medical Biostatistics, Epidemiology and Informatics, Mainz (Germany); National Research Council, Institute of Clinical Physiology, Lecce (Italy); Jablonka, K. [Klinikum Bremen-Mitte, Klinik fuer Radiologische Diagnostik und Nuklearmedizin, Bremen (Germany); Jahnen, A. [Centre de Recherche Public Henri Tudor, Luxembourg (Luxembourg); Langer, M. [Universitaetsklinikum Freiburg, Klinik fuer Radiologie, Freiburg (Germany); Laniado, M. [Universitaetsklinikum Carl Gustav Carus Dresden, Institut und Poliklinik fuer Radiologische Diagnostik, Dresden (Germany); Lotz, J. [Universitaetsmedizin Goettingen, Institut fuer Diagnostische und Interventionelle Radiologie, Goettingen (Germany); Mentzel, H.J. [Universitaetsklinikum Jena, Institut fuer Diagnostische und Interventionelle Radiologie, Sektion Kinderradiologie, Jena (Germany); Queisser-Wahrendorf, A. [Universitaetsmedizin Mainz, Zentrum fuer Kinder- und Jugendmedizin, Mainz (Germany); Rompel, O. [Universitaetsklinikum Erlangen, Radiologisches Institut, Erlangen (Germany); Schlick, I. [Klinikum Nuernberg Sued, Institut fuer Radiologie und Neuroradiologie, Nuremberg (Germany); Schneider, K.; Seidenbusch, M. [Institut fuer Klinische Radiologie, Klinikum der Universitaet Muenchen, Dr. von Haunersches Kinderspital, Munich (Germany); Schumacher, M. [Universitaetsklinik Freiburg, Klinik fuer Neuroradiologie, Neurozentrum, Freiburg (Germany); Spix, C. [University Medical Center Mainz, German Childhood Cancer Registry, Mainz (Germany); Spors, B. [Charite - Universitaetsmedizin Berlin, Kinderradiologie, Standort Campus Virchow Klinikum, Berlin (Germany); Staatz, G. [Universitaetsmedizin Mainz, Klinik und Poliklinik fuer diagnostische und interventionelle Radiologie, Sektion Kinderradiologie, Mainz (Germany); Vogl, T. [Klinikum der Johann Wolfgang Goethe-Universitaet Frankfurt/Main, Institut fuer Diagnostische und Interventionelle Radiologie, Frankfurt (Germany); Wagner, J. [Vivantes, Klinikum im Friedrichshain, Institut fuer Radiologie und Interventionelle Therapie, Berlin (Germany); Weisser, G. [Universitaetsklinikum Mannheim, Institut fuer Klinische Radiologie und Nuklearmedizin, Mannheim (Germany)

2015-03-15

The aim of this cohort study was to assess the risk of developing cancer, specifically leukaemia, tumours of the central nervous system and lymphoma, before the age of 15 years in children previously exposed to computed tomography (CT) in Germany. Data for children with at least one CT between 1980 and 2010 were abstracted from 20 hospitals. Cancer cases occurring between 1980 and 2010 were identified by stochastic linkage with the German Childhood Cancer Registry (GCCR). For all cases and a sample of non-cases, radiology reports were reviewed to assess the underlying medical conditions at time of the CT. Cases were only included if diagnosis occurred at least 2 years after the first CT and no signs of cancer were recorded in the radiology reports. Standardised incidence ratios (SIR) using incidence rates from the general population were estimated. The cohort included information on 71,073 CT examinations in 44,584 children contributing 161,407 person-years at risk with 46 cases initially identified through linkage with the GCCR. Seven cases had to be excluded due to signs possibly suggestive of cancer at the time of first CT. Overall, more cancer cases were observed (O) than expected (E), but this was mainly driven by unexpected and possibly biased results for lymphomas. For leukaemia, the SIR (SIR = O/E) was 1.72 (95 % CI 0.89-3.01, O = 12), and for CNS tumours, the SIR was 1.35 (95 % CI 0.54-2.78, O = 7). Despite careful examination of the medical information, confounding by indication or reverse causation cannot be ruled out completely and may explain parts of the excess. Furthermore, the CT exposure may have been underestimated as only data from the participating clinics were available. This should be taken into account when interpreting risk estimates. (orig.)

Analyzing the severity of accidents on the German Autobahn.

Science.gov (United States)

Manner, Hans; Wünsch-Ziegler, Laura

2013-08-01

We study the severity of accidents on the German Autobahn in the state of North Rhine-Westphalia using data for the years 2009 until 2011. We use a multinomial logit model to identify statistically relevant factors explaining the severity of the most severe injury, which is classified into the four classes fatal, severe injury, light injury and property damage. Furthermore, to account for unobserved heterogeneity we use a random parameter model. We study the effect of a number of factors including traffic information, road conditions, type of accidents, speed limits, presence of intelligent traffic control systems, age and gender of the driver and location of the accident. Our findings are in line with studies in different settings and indicate that accidents during daylight and at interchanges or construction sites are less severe in general. Accidents caused by the collision with roadside objects, involving pedestrians and motorcycles, or caused by bad sight conditions tend to be more severe. We discuss the measures of the 2011 German traffic safety programm in the light of our results. Copyright © 2013 Elsevier Ltd. All rights reserved.

Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation.

Science.gov (United States)

Müller, Dirk; Danner, Marion; Rhiem, Kerstin; Stollenwerk, Björn; Engel, Christoph; Rasche, Linda; Borsi, Lisa; Schmutzler, Rita; Stock, Stephanie

2018-04-01

Women with a BRCA1 or BRCA2 mutation are at increased risk of developing breast and/or ovarian cancer. This economic modeling study evaluated different preventive interventions for 30-year-old women with a confirmed BRCA (1 or 2) mutation. A Markov model was developed to estimate the costs and benefits [i.e., quality-adjusted life years (QALYs), and life years gained (LYG)] associated with prophylactic bilateral mastectomy (BM), prophylactic bilateral salpingo-oophorectomy (BSO), BM plus BSO, BM plus BSO at age 40, and intensified surveillance. Relevant input data was obtained from a large German database including 5902 women with BRCA 1 or 2, and from the literature. The analysis was performed from the German Statutory Health Insurance (SHI) perspective. In order to assess the robustness of the results, deterministic and probabilistic sensitivity analyses were performed. With costs of €29,434 and a gain in QALYs of 17.7 (LYG 19.9), BM plus BSO at age 30 was less expensive and more effective than the other strategies, followed by BM plus BSO at age 40. Women who were offered the surveillance strategy had the highest costs at the lowest gain in QALYs/LYS. In the probabilistic sensitivity analysis, the probability of cost-saving was 57% for BM plus BSO. At a WTP of 10,000 € per QALY, the probability of the intervention being cost-effective was 80%. From the SHI perspective, undergoing BM plus immediate BSO should be recommended to BRCA 1 or 2 mutation carriers due to its favorable comparative cost-effectiveness.

Statistical study on cancer patients of cancer research hospital

International Nuclear Information System (INIS)

Shim, Yoon Sang; Choi, Soo Yong; Won, Hyuk; Kim, Kee Hwa

1991-01-01

The total number of malignant neoplasms included on this study 7,787 cases(10.4%) among 74,928 cases for 2 years. On sex, females with 57.6% were much more than males with 42.4%. The highest proportion of cancer 50-59 age group. The most frequent primary site among males was found to be stomach with 36.2%, followed by liver(12.3%), lung(12.2%), esophagus(15.5%) and larynx(4.9%). In females, the first order was uterine cervix with 47.3%, followed most common type of morphology of malignant neoplasms was adenocarcinoma(39.0%) in males an squamous cell carcinoma(56.2%) in females. Among the cancer patients initially diagnosed in this hospital, the proportion of malignant neoplasms by the extent of disease was 4.6% for patient with carcinoma-in-situ, 76.3% for patients with localized involvement, 11.6% for patients with regional involvement and 7.5% for patients with distant involvement. Among,the cancer patients initially treatment in this hospital, the proportion of malignant neoplasms by the method of treatment was 19.0% for surgery, 27.7 for radiotherapy and 24.2% for chemotherapy. Among the cancer patients confirmed by medical records, 11.2% was traced more than 5 years. (Author)

Childhood cancer in the vicinity of nuclear power plants. Results of a German study in perspective; Kinderkanker in de omgeving van kerncentrales. Resultaten van een Duitse studie in perspectief

Energy Technology Data Exchange (ETDEWEB)

Dekkers, S.A.J.; Slaper, H.; Tanzi, C.P.

2010-09-15

Whether or not childhood cancer occurs more frequently in the vicinity of nuclear power plants remains uncertain. The results of a German study completed in 2007 that found a significantly increased risk of disease are not confirmed in British and French investigations. This follows from work carried out at RIVM. In the German study, the so-called KiKK-study, the number of cases of childhood cancer in the vicinity of sixteen German nuclear power plants in recent decades was investigated. The study showed that children under the age of five who live within five kilometers of a nuclear power plant are at an increased risk of developing childhood cancer. The authors of the study are unable to explain this risk, which cannot be explained as an effect of the extremely limited extra radiation produced by a nuclear power plant. After publication of the KiKK-study's results questions were asked in Dutch parliament. The minister of VROM (housing, spatial planning and the environment) in response to these questions asked RIVM to compare the results of the German study with those of other studies and to give extra attention to the situation in the vicinity of Borssele, the location of the only Dutch nuclear power plant. In Borssele, circa three hundred children under the age of five live within five kilometers of the nuclear power plant. If the risk observed in Germany is applicable to the nuclear power plant at Borssele, one extra case of childhood cancer could be expected every thirty years. Epidemiological research would not be able to determine a frequency that low. A person living in the vicinity of the nuclear power plant at Borssele incurs less radiation from the power plant during a year, than the average dose a Dutch citizen receives in a single day from natural sources. The extra risk observed in Germany cannot be explained as the effect of such a low dose. [Dutch] Of kinderkanker nabij kerncentrales vaker voorkomt blijft onzeker. Het resultaat van een Duits

Validation of the German Diabetes Risk Score within a population-based representative cohort.

Science.gov (United States)

Hartwig, S; Kuss, O; Tiller, D; Greiser, K H; Schulze, M B; Dierkes, J; Werdan, K; Haerting, J; Kluttig, A

2013-09-01

To validate the German Diabetes Risk Score within the population-based cohort of the Cardiovascular Disease - Living and Ageing in Halle (CARLA) study. The sample included 582 women and 719 men, aged 45-83 years, who did not have diabetes at baseline. The individual risk of every participant was calculated using the German Diabetes Risk Score, which was modified for 4 years of follow-up. Predicted probabilities and observed outcomes were compared using Hosmer-Lemeshow goodness-of-fit tests and receiver-operator characteristic analyses. Changes in prediction power were investigated by expanding the German Diabetes Risk Score to include metabolic variables and by subgroup analyses. We found 58 cases of incident diabetes. The median 4-year probability of developing diabetes based on the German Diabetes Risk Score was 6.5%. The observed and predicted probabilities of developing diabetes were similar, although estimation was imprecise owing to the small number of cases, and the Hosmer-Lemeshow test returned a poor correlation (chi-squared = 55.3; P = 5.8*10⁻¹²). The area under the receiver-operator characteristic curve (AUC) was 0.70 (95% CI 0.64-0.77), and after excluding participants ≥66 years old, the AUC increased to 0.77 (95% CI 0.70-0.84). Consideration of glycaemic diagnostic variables, in addition to self-reported diabetes, reduced the AUC to 0.65 (95% CI 0.58-0.71). A new model that included the German Diabetes Risk Score and blood glucose concentration (AUC 0.81; 95% CI 0.76-0.86) or HbA(1c) concentration (AUC 0.84; 95% CI 0.80-0.91) was found to peform better. Application of the German Diabetes Risk Score in the CARLA cohort did not reproduce the findings in the European Prospective Investigation into Cancer and Nutrition (EPIC) Potsdam study, which may be explained by cohort differences and model overfit in the latter; however, a high score does provide an indication of increased risk of diabetes. © 2013 The Authors. Diabetic Medicine © 2013 Diabetes

How German Online Retailers Price Foods: An Empirical Analysis for Chocolate Products

Directory of Open Access Journals (Sweden)

Svetlana Fedoseeva

2017-01-01

Full Text Available Despite the increasing importance of online grocery retailing, little is known about price dispersion across online providers, the relation between online and offline prices as well as the frequency of price adjustments. We employ means of descriptive and inductive statistics as well as panel econometrics to address these issues for German online food retailers. Daily online prices for twelve chocolate products charged by eight pure online and multichannel retailers and collected over three months are investigated. Information economics suggests that a maturing online market will call forth more price homogeneity online due to lower search costs by consumers as well as more flexible prices due to lower costs of price adjustments by retailers. Our results suggest, however, that neither homogenous prices nor frequent price adjustments do occur on the German online chocolate market.

A hypothesis to explain childhood cancers near nuclear power plants

International Nuclear Information System (INIS)

Fairlie, Ian

2014-01-01

Over 60 epidemiological studies world-wide have examined cancer incidences in children near nuclear power plants (NPPs): most of them indicate leukemia increases. These include the 2008 KiKK study commissioned by the German Government which found relative risks (RR) of 1.6 in total cancers and 2.2 in leukemias among infants living within 5 km of all German NPPs. The KiKK study has retriggered the debate as to the cause(s) of these increased cancers. A suggested hypothesis is that the increased cancers arise from radiation exposures to pregnant women near NPPs. However any theory has to account for the >10,000 fold discrepancy between official dose estimates from NPP emissions and observed increased risks. An explanation may be that doses from spikes in NPP radionuclide emissions are significantly larger than those estimated by official models which are diluted through the use of annual averages. In addition, risks to embryos/fetuses are greater than those to adults and haematopoietic tissues appear more radiosensitive in embryos/fetuses than in newborn babies. The product of possible increased doses and possible increased risks per dose may provide an explanation. - Highlights: • Over 60 studies worldwide on increased cancers near nuclear power plants (NPPs). • German government KiKK study provides very strong evidence. • Hypothesis proposes cancers arise in pregnant women near NPPs. • Nuclide spikes during refuelling could result in increased exposures. • Explanation offered for discrepancy between small dose estimates and large risks

A language that forgot itself (Essay on the curious non-existence of German as a recognized minority language in today’s Poland

Directory of Open Access Journals (Sweden)

Tomasz Kamusella

2014-12-01

Full Text Available A language that forgot itself  (Essay on the curious non-existence of German as a recognized minority language in today’s Poland This essay draws on my almost three decades worth of research on the multiethnic and multilingual history of Upper Silesia during the last two centuries, when various ethnolinguistic nationalisms have radically altered the ethnic, political, demographic and linguistic shape of the region. I focus on the German minority that was recognized in Poland in the early 1990s. This recognition was extended to the German language. However, though in official statistics there are hundreds of schools with German, and bilingual signage amply dots the Upper Silesian landscape, neither in the region nor elsewhere in Poland is there a single, however small, locality where German would be the language of everyday communication. With this essay I attempt to explicate this irony of official recognition on the one hand, and the tacitly enforced non-existence on the ground, on the other hand.

African Americans Who Teach German Language and Culture.

Science.gov (United States)

Fikes, Robert Jr.

2001-01-01

A large number of black scholars have pursued advanced degrees in the German language, history, and culture. Describes the history of African American interest in the German language and culture, highlighting various black scholars who have studied German over the years. Presents data on African Americans in German graduate programs and examines…

German energy market 2016

International Nuclear Information System (INIS)

Schiffer, Hans-Wilhelm; Weltenergierat, Berlin

2017-01-01

The basic orientation of the German energy supply to the increased use of renewable energies, while increasing energy efficiency, is prediscribed by the German government's energy concept and determines the market development. A current overview of the German energy market is given, which provides also this year a concentrated Compilation of the key data of the energy industry. As in the years before, the article not only summarizes general facts about the energy mix, but also goes into detail on the development of the individual energy sources, petroleum, natural gas, brown coal and hard coal, electricity as well as renewable energies. Furthermore, the price trends of international markets and in the domestic market are explained. A current overview of the development of greenhouse gas emissions concludes the contribution. [de

A Generic Data Harmonization Process for Cross-linked Research and Network Interaction. Construction and Application for the Lung Cancer Phenotype Database of the German Center for Lung Research.

Science.gov (United States)

Firnkorn, D; Ganzinger, M; Muley, T; Thomas, M; Knaup, P

2015-01-01

Joint data analysis is a key requirement in medical research networks. Data are available in heterogeneous formats at each network partner and their harmonization is often rather complex. The objective of our paper is to provide a generic approach for the harmonization process in research networks. We applied the process when harmonizing data from three sites for the Lung Cancer Phenotype Database within the German Center for Lung Research. We developed a spreadsheet-based solution as tool to support the harmonization process for lung cancer data and a data integration procedure based on Talend Open Studio. The harmonization process consists of eight steps describing a systematic approach for defining and reviewing source data elements and standardizing common data elements. The steps for defining common data elements and harmonizing them with local data definitions are repeated until consensus is reached. Application of this process for building the phenotype database led to a common basic data set on lung cancer with 285 structured parameters. The Lung Cancer Phenotype Database was realized as an i2b2 research data warehouse. Data harmonization is a challenging task requiring informatics skills as well as domain knowledge. Our approach facilitates data harmonization by providing guidance through a uniform process that can be applied in a wide range of projects.

Determinants and implications of cancer patients' psychosocial needs.

Science.gov (United States)

Ernstmann, N; Neumann, M; Ommen, O; Galushko, M; Wirtz, M; Voltz, R; Hallek, M; Pfaff, H

2009-11-01

Cancer patients often experience distress. However, the majority of newly diagnosed patients gradually adapt to the crisis. When symptoms of distress and anxiety persist over months, patients require psychosocial support. The aim of the present study was to determine the proportion of cancer patients who indicate the need for psychosocial support and to identify sociodemographic, psychological and illness-related factors predicting the need for psychosocial support in a German sample. The cross-sectional retrospective study was administered to 710 cancer patients who had been inpatients at the University Hospital of Cologne. The response rate was 49.5%. Patients suffering from bronchial, oesophageal, colorectal, breast, prostate and skin cancer participated in the study. The severity of depressive symptoms was assessed using the German version of the Major Depression Inventory. The level of anxiety was assessed with the state subscale of the German version of the State-Trait Anxiety Inventory. To measure the functional aspects of health-related quality of life, the scales "physical functioning", "role functioning", "emotional functioning", "cognitive functioning" and "role functioning" of the European Organisation for Research and Treatment of Cancer QLQ-C30 Questionnaire (EORTC QLQ-C30) were used. Of the cancer patients, 18.9% indicate an unmet need for psychosocial support and 9.5% are actually using psychosocial services. In a multiple logistic regression, significant indicators of the need for psychosocial support are gender [p = 0.014; standardised effect coefficient (sc) = 1.615] and emotional functioning (p Emotional functioning is a central predictor of the requirement for psychosocial support. Women are emotionally more affected than men and need more psychosocial support. The prognostic validity of the severity of depression and anxiety is limited.

Assisted reproductive techniques and risk of exstrophy-epispadias complex: a German case-control study.

Science.gov (United States)

Zwink, Nadine; Jenetzky, Ekkehart; Hirsch, Karin; Reifferscheid, Peter; Schmiedeke, Eberhard; Schmidt, Dominik; Reckin, Sabrina; Obermayr, Florian; Boemers, Thomas M; Stein, Raimund; Reutter, Heiko; Rösch, Wolfgang H; Brenner, Hermann; Ebert, Anne-Karoline

2013-04-01

We assessed the risk of exstrophy-epispadias complex in children conceived by in vitro fertilization or intracytoplasmic sperm injection. Data from the German Network for Congenital Uro-REctal malformations were compared to nationwide data from the German In Vitro Fertilization Register and the German Federal Statistical Office. Odds ratios (95% CI) were determined to quantify associations using logistic regression. A total of 123 patients with exstrophy-epispadias complex born in Germany between 1997 and 2011 were recruited through participating departments of pediatric urology and pediatric surgery throughout the country as well as the German self-help organizations Blasenekstrophie/Epispadie e.V. and Kloakenekstrophie. All German live births (10,069,986) between 1997 and 2010 comprised the controls. Overall, 12 subjects (10%) and 129,982 controls (1%) were conceived by in vitro fertilization or intracytoplasmic sperm injection. Conception by assisted reproductive technique was associated with a more than eightfold increased risk of exstrophy-epispadias complex compared to spontaneous conception (OR 8.3, 95% CI 4.6-15.0, p risk of exstrophy-epispadias complex in children conceived by in vitro fertilization (OR 14.0, 95% CI 6.5-30.0, p study provides evidence that assisted reproductive techniques such as in vitro fertilization and intracytoplasmic sperm injection are associated with a markedly increased risk of having a child born with exstrophy-epispadias complex. However, it remains unclear whether this finding may be due to assisted reproduction per se and/or underlying infertility/subfertility etiology or parent characteristics. Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

German Business in Russia

Directory of Open Access Journals (Sweden)

Irakliy D. Gvazava

2013-01-01

Full Text Available Since Perestroika German-Russian relationships have been steadily developing fueled by close contacts between the leaders of both countries. Boris Yeltsin and Helmut Kohl, Vladimir Putin and Gerhard Schröder, Dmitry Medvedev and Angela Merkel had friendly relations resulted in some fruitful business projects, intergovernmental economic forums etc. In my article I will consider the activities of German companies in Russia, advantages, barriers and expectations

A review of the results from the German Wismut uranium miners cohort

International Nuclear Information System (INIS)

Walsh, L.; Grosche, B.; Schnelzer, M.; Tschense, A.; Sogl, M.; Kreuzer, M.

2015-01-01

The Wismut cohort is currently the largest single study on the health risks associated with occupational exposures to ionising radiation and dust accrued during activities related to uranium mining. The cohort has ∼59 000 male workers, first employed between 1946 and 1989, at the Wismut Company in Germany. The main effect is a statistically significant increase in mortality from lung cancer with both increasing cumulative radon exposure and silica dust exposure. Risks for cancers of the extra-thoracic airways, all extra-pulmonary cancers and cardiovascular diseases associated with radiation exposures have been evaluated. Cohort mortality rates for some other cancer sites, stomach and liver, are statistically significantly increased in relation to the general population, but not statistically significantly related to occupational exposures. No associations between leukaemia mortality and occupational doses of ionising radiation were found. (authors)

The German version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR).

Science.gov (United States)

Holzinger, Dirk; Foell, Dirk; Horneff, Gerd; Foeldvari, Ivan; Tzaribachev, Nikolay; Tzaribachev, Catrin; Minden, Kirsten; Kallinich, Tilmann; Ganser, Gerd; Clara, Lucia; Haas, Johannes-Peter; Hügle, Boris; Huppertz, Hans-Iko; Weller, Frank; Consolaro, Alessandro; Bovis, Francesca; Ruperto, Nicolino

2018-04-01

The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patient versions of the JAMAR in the German language. The reading comprehension of the questionnaire was tested in 10 JIA parents and patients. The participating centres were asked to collect demographic and clinical data along the JAMAR questionnaire in 100 consecutive JIA patients or all consecutive patients seen in a 6-month period and to administer the JAMAR to 100 healthy children and their parents. The statistical validation phase explored descriptive statistics and the psychometric issues of the JAMAR: the three Likert assumptions, floor/ceiling effects, internal consistency, Cronbach's alpha, interscale correlations, test-retest reliability, and construct validity (convergent and discriminant validity). A total of 319 JIA patients (2.8% systemic, 36.7% oligoarticular, 23.5% RF negative polyarthritis, and 37% other categories) and 100 healthy children were enrolled in eight centres. The JAMAR components discriminated well healthy subjects from JIA patients. All JAMAR components revealed good psychometric performances. In conclusion, the German version of the JAMAR is a valid tool for the assessment of children with JIA and is suitable for use both in routine clinical practice and in clinical research.

Risk of cancer incidence before the age of 15 years after exposure to ionising radiation from computed tomography: results from a German cohort study.

Science.gov (United States)

Krille, L; Dreger, S; Schindel, R; Albrecht, T; Asmussen, M; Barkhausen, J; Berthold, J D; Chavan, A; Claussen, C; Forsting, M; Gianicolo, E A L; Jablonka, K; Jahnen, A; Langer, M; Laniado, M; Lotz, J; Mentzel, H J; Queißer-Wahrendorf, A; Rompel, O; Schlick, I; Schneider, K; Schumacher, M; Seidenbusch, M; Spix, C; Spors, B; Staatz, G; Vogl, T; Wagner, J; Weisser, G; Zeeb, H; Blettner, M

2015-03-01

The aim of this cohort study was to assess the risk of developing cancer, specifically leukaemia, tumours of the central nervous system and lymphoma, before the age of 15 years in children previously exposed to computed tomography (CT) in Germany. Data for children with at least one CT between 1980 and 2010 were abstracted from 20 hospitals. Cancer cases occurring between 1980 and 2010 were identified by stochastic linkage with the German Childhood Cancer Registry (GCCR). For all cases and a sample of non-cases, radiology reports were reviewed to assess the underlying medical conditions at time of the CT. Cases were only included if diagnosis occurred at least 2 years after the first CT and no signs of cancer were recorded in the radiology reports. Standardised incidence ratios (SIR) using incidence rates from the general population were estimated. The cohort included information on 71,073 CT examinations in 44,584 children contributing 161,407 person-years at risk with 46 cases initially identified through linkage with the GCCR. Seven cases had to be excluded due to signs possibly suggestive of cancer at the time of first CT. Overall, more cancer cases were observed (O) than expected (E), but this was mainly driven by unexpected and possibly biased results for lymphomas. For leukaemia, the SIR (SIR = O/E) was 1.72 (95 % CI 0.89-3.01, O = 12), and for CNS tumours, the SIR was 1.35 (95 % CI 0.54-2.78, O = 7). Despite careful examination of the medical information, confounding by indication or reverse causation cannot be ruled out completely and may explain parts of the excess. Furthermore, the CT exposure may have been underestimated as only data from the participating clinics were available. This should be taken into account when interpreting risk estimates.

Statistical study on cancer patients of cancer research hospital

International Nuclear Information System (INIS)

Shim, Yun Sang; Choi, Soo Yong; Kim, Ki Wha; Kang, Sung Mok

1993-01-01

The total number of malignant neoplasms included in this study 15,737 cases(11.8%) among 133,251 cases for 3 years. On sex, females with 52.9% were much more than males with 47.1%. The highest proportion of cancer patients by age was 33.7% in males and 28.5% in females, respectivelty for 50-59 age group. The most frequent primary site among males was found to be stomach with 35.5%, followed by liver(14.7%), lung(13.0%), esophagus(5.4%) and colon (3.2%). In females, the first order was uterine cervix with 40.6%, followed by stomach(17.2%), breast(14.4), rectum(3.7%) and lung(3.4%). The most common type of morphology of malignant neoplasms was adenocarcinoma(47.4%) in males an squamous cell carcinoma(58.0%) in females. Among the cancer patients initially diagnosed in this hospital, the proportion of malignant neoplasms by the exent of disease was 2.5% for patient with carcinoma-in-situ, 54.1% for patients with localized involvement, 13.3% for patients with regional involvement and 8.5% for patients with distant involvement. Among the cancer patients initially treatment in this hospital, the proportion of malignant neoplasms by the method of treatment was 23.6% for surgery, 25.3% for radiotherapy and 30.3% for chemotherapy. Among the cancer patients confirmed by medical records, 7.7% was traced more than 5 years. (Author)

Palliative systemic therapy and overall survival of 1,395 patients with advanced breast cancer - Results from the prospective German TMK cohort study.

Science.gov (United States)

Fietz, Thomas; Tesch, Hans; Rauh, Jacqueline; Boller, Emil; Kruggel, Lisa; Jänicke, Martina; Marschner, Norbert

2017-08-01

Data on treatment and outcome of advanced breast cancer in routine practice are rare, especially concerning recurrent disease, but important to complement the results from clinical trials and to improve the standard of care. We present data on choice of systemic first-line treatment, number of treatment lines, and survival of patients treated by medical oncologists in Germany. 1395 patients recruited by 124 sites at start of first-line therapy into the ongoing, prospective German clinical cohort study TMK (Tumour Registry Breast Cancer) between February 2007 and October 2015 were analysed. The median OS was 33.8 months (95% CI 30.2-40.2) for HR-positive/HER2-negative, 38.2 months (95% CI 31.3-43.0) for HER2-positive and 16.8 months (95% CI 11.5-22.0) for triple negative breast cancer. Patients with triple negative tumours more often died before start of a third-line therapy than patients with HR-positive or HER2-positive tumours (44% vs. 25%). Use of taxane-based chemotherapies has increased since 2007, with 65% of all first-line chemotherapy-treatments containing taxanes in 2013-15 (60% HR-positive/HER2-negative, 75% HER2-positive, 56% triple negative). 52% of the patients with HR-positive/HER2-negative tumours received first-line endocrine therapy in 2013-15; when restricted to patients with only non-visceral metastases this percentage increased to 63%. To our knowledge, this is the first cohort study showing systemic first-line therapy for all subtypes of advanced breast cancer. Overall survival in the TMK is comparable to that reported by clinical trials despite the inclusion of older and comorbid patients. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

A Suggested Curriculum Outline for German in Secondary Schools

Science.gov (United States)

Clutterbuck, J. M.

1975-01-01

Outlines a four-year program of German study aiming to give students a basic ability in spoken and written German, knowledge of German culture, and preparation for advanced German study. Study topics and textbooks are included. (CHK)

Analyzing quality of colorectal cancer care through registry statistics: a small community hospital example.

Science.gov (United States)

Hopewood, Ian

2011-01-01

As the quantity of elderly Americans requiring oncologic care grows, and as cancer treatment and medicine become more advanced, assessing quality of cancer care becomes a necessary and advantageous practice for any facility.' Such analysis is especially practical in small community hospitals, which may not have the resources of their larger academic counterparts to ensure that the care being provided is current and competitive in terms of both technique and outcome. This study is a comparison of the colorectal cancer care at one such center, Falmouth Community Hospital (FCH)--located in Falmouth, Massachusetts, about an hour and a half away from the nearest metropolitan center--to the care provided at a major nearby Boston Tertiary Center (BTC) and at teaching and research facilities across New England and the United States. The metrics used to measure performance encompass both outcome (survival rate data) as well as technique, including quality of surgery (number of lymph nodes removed) and the administration of adjuvant treatments, chemotherapy, and radiation therapy, as per national guidelines. All data for comparison between FCH and BTC were culled from those hospitals' tumor registries. Data for the comparison between FCH and national tertiary/referral centers were taken from the American College of Surgeons' Commission on Cancer, namely National Cancer Data Base (NCDB) statistics, Hospital Benchmark Reports and Practice Profile Reports. The results showed that, while patients at FCH were diagnosed at both a higher age and at a more advanced stage of colorectal cancer than their BTC counterparts, FCH stands up favorably to BTC and other large centers in terms of the metrics referenced above. Quality assessment such as the analysis conducted here can be used at other community facilities to spotlight, and ultimately eliminate, deficiencies in cancer programs.

How old are Germanic lambs?

DEFF Research Database (Denmark)

Vrieland, Seán D.

2017-01-01

Gothic and Gutnish lamb with the meaning ‘sheep’ sets these two languages apart from the rest of Germanic, and is the most common piece of evidence used to claim they share a close connection. Yet the same meaning is found in the descendants of Proto-Fennic *lambaz, a loan from Proto-Germanic, an......Gothic and Gutnish lamb with the meaning ‘sheep’ sets these two languages apart from the rest of Germanic, and is the most common piece of evidence used to claim they share a close connection. Yet the same meaning is found in the descendants of Proto-Fennic *lambaz, a loan from Proto...

[Adjustment of the German DRG system in 2009].

Science.gov (United States)

Wenke, A; Franz, D; Pühse, G; Volkmer, B; Roeder, N

2009-07-01

The 2009 version of the German DRG system brought significant changes for urology concerning coding of diagnoses, medical procedures and the DRG structure. In view of the political situation and considerable economic pressure, a critical analysis of the 2009 German DRG system is warranted. Analysis of relevant diagnoses, medical procedures and G-DRGs in the versions 2008 and 2009 based on the publications of the German DRG-institute (InEK) and the German Institute of Medical Documentation and Information (DIMDI). The relevant diagnoses, medical procedures and German DRGs in the versions 2008 and 2009 were analysed based on the publications of the German DRG Institute (InEK) and the German Institute of Medical Documentation and Information (DIMDI). Changes for 2009 focus on the development of the DRG structure, DRG validation and codes for medical procedures to be used for very complex cases. The outcome of these changes for German hospitals may vary depending in the range of activities. The German DRG system again gained complexity. High demands are made on correct and complete coding of complex urology cases. The quality of case allocation in the German DRG system was improved. On the one hand some of the old problems (e.g. enterostomata) still persist, while on the other hand new problems evolved out of the attempt to improve the case allocation of highly complex and expensive cases. Time will tell whether the increase in highly specialized DRG with low case numbers will continue to endure and reach acceptable rates of annual fluctuations.

German Vocabulary.

Science.gov (United States)

Coombs, Virginia M.

This article discusses in general terms derivational aspects of English vocabulary. Citing examples of Anglo-Saxon origin, the author provides a glimpse into the nature of the interrelatedness of English, German, and French vocabulary. (RL)

Belief In Numbers: When and why women disbelieve tailored breast cancer risk statistics

Science.gov (United States)

Scherer, Laura D.; Ubel, Peter A.; McClure, Jennifer; Green, Sarah M.; Alford, Sharon Hensley; Holtzman, Lisa; Exe, Nicole; Fagerlin, Angela

2013-01-01

Objective To examine when and why women disbelieve tailored information about their risk of developing breast cancer. Methods 690 women participated in an online program to learn about medications that can reduce the risk of breast cancer. The program presented tailored information about each woman’s personal breast cancer risk. Half of women were told how their risk numbers were calculated, whereas the rest were not. Later, they were asked whether they believed that the program was personalized, and whether they believed their risk numbers. If a woman did not believe her risk numbers, she was asked to explain why. Results Beliefs that the program was personalized were enhanced by explaining the risk calculation methods in more detail. Nonetheless, nearly 20% of women did not believe their personalized risk numbers. The most common reason for rejecting the risk estimate was a belief that it did not fully account for personal and family history. Conclusions The benefits of tailored risk statistics may be attenuated by a tendency for people to be skeptical that these risk estimates apply to them personally. Practice Implications Decision aids may provide risk information that is not accepted by patients, but addressing the patients’ personal circumstances may lead to greater acceptance. PMID:23623330

5 year radar-based rainfall statistics: disturbances analysis and development of a post-correction scheme for the German radar composite

Science.gov (United States)

Wagner, A.; Seltmann, J.; Kunstmann, H.

2015-02-01

A radar-based rainfall statistic demands high quality data that provide realistic precipitation amounts in space and time. Instead of correcting single radar images, we developed a post-correction scheme for long-term composite radar data that corrects corrupted areas, but preserves the original precipitation patterns. The post-correction scheme is based on a 5 year statistical analysis of radar composite data and its constituents. The accumulation of radar images reveals artificial effects that are not visible in the individual radar images. Some of them are already inherent to single radar data such as the effect of increasing beam height, beam blockage or clutter remnants. More artificial effects are introduced in the process of compositing such as sharp gradients at the boundaries of overlapping areas due to different beam heights and resolution. The cause of these disturbances, their behaviour with respect to reflectivity level, season or altitude is analysed based on time-series of two radar products: the single radar reflectivity product PX for each of the 16 radar systems of the German Meteorological Service (DWD) for the time span 2000 to 2006 and the radar composite product RX of DWD from 2005 through to 2009. These statistics result in additional quality information on radar data that is not available elsewhere. The resulting robust characteristics of disturbances, e.g. the dependency of the frequencies of occurrence of radar reflectivities on beam height, are then used as a basis for the post-correction algorithm. The scheme comprises corrections for shading effects and speckles, such as clutter remnants or overfiltering, as well as for systematic differences in frequencies of occurrence of radar reflectivities between the near and the far ranges of individual radar sites. An adjustment to rain gauges is also included. Applying this correction, the Root-Mean-Square-Error for the comparison of radar derived annual rain amounts with rain gauge data

Comparison of the most popular Czech and German lexemes in the global Internet search engine Google

Directory of Open Access Journals (Sweden)

Dana Gálová

2017-11-01

Full Text Available Most widely used search engine Google represents the most current language databank in the world. It publishes annually the statistics of the most popular words that indicate interest preferences of a particular population in a given year. The aim of this paper is a comparative analysis of the most popular lexemes in Czech and German versions of search engine Google in 2015. Lexeme segmentation into different thematic fields enabled the identification of correspondences and differences and thus the comparison of interest preferences of Czech and German population. The paper also offers mutual interpretation of differences and reflection on the causes of different extents of civic engagement in both populations.

Experience and results of MELCOR application for German PWRs

International Nuclear Information System (INIS)

Sonnenkalb, M.

1999-01-01

An introduction into severe accident research work performed at GRS with regard to the use of the MELCOR code is given in Chapter One of the paper. Experience in applying MELCOR 1.8.3 for German PWRs and results of MELCOR calculations done within the project 'Accident management - Mitigation' for German LWRs are presented in Chapter Two. This 3-year project was finished February 1998. It was funded by the German Ministry for Environment, Nature Conservation and Nuclear Safety - BMU. In Chapter Three, a short overview of a training course on 'Phenomenology of Severe Accidents in PWR-Plants' is given. Mainly due to the interest from German NPPs GRS developed this special training session in 1996. Since 1996 it has been held several times for operators, shift personnel and the management board of two different German NPPs and for lecture of the German NPP training centre in Essen. In Chapter Four, results of the application of MELCOR 1.8.4 for German PWRs are presented. This work is done within a new project on 'Accident Management - Mitigation' for German LWRs. It was started in March 1998 and is again funded by the German Federal Ministry BMU. An objective of this project is to perform further MELCOR calculations, to be used within a PSA level 2 study for a German PWR, which is done at GRS in parallel. The experience of using MELCOR for German PWRs are summarised in Chapter Five. (author)

The German model of capitalism and the persistence of outward foreign direct investment: evidence from German manufacturing industries

Directory of Open Access Journals (Sweden)

Martin T Bohl

2011-06-01

Full Text Available Against the backdrop of critique on the German model of capitalism in general, and German public policy in particular as to the ability to successfully adjust to rapid change and exogenous shocks in wake of economic globalisation, this paper investigates the degree of shock persistence in foreign direct investment (FDI of ten German manufacturing industries for the period 1976 to 2003. Theory on exports and non-FDI investment suggests that FDI should exhibit a considerable degree of shock persistence because they are subject to high sunk costs because of high entry and exit costs associated with the high level of asset specificity that is normally connected to FDI. Persistence in foreign direct investment time series data is established by applying various unit root tests. The results are robust to the potential presence of structural breaks in the data. The empirical analysis shows that German outward FDI in mature manufacturing industries, with one exception, exhibits a high degree of shock persistence. The results suggest, at least for mature German industries, that the sunk costs view on shock persistency is confirmed for outward FDI. The results furnish evidence for a tentative assessment of the relationship between German public policy and FDI strategies of multinational firms.

USA: German in the Changing Landscape of Postsecondary Education

Science.gov (United States)

Tatlock, Lynne

2010-01-01

This article identifies recent indicators of the state of German Studies in the United States with special attention to postsecondary enrollments in German. It additionally reviews challenges to the postsecondary teaching of German as they manifest themselves both locally and nationally, including the positioning of German Studies in the life of…

Comparison between Dutch and German buildings

Energy Technology Data Exchange (ETDEWEB)

Lony, R.J.M.; Molenaar, D.J.; Rietkerk, J.; Schuiling, D.J.B.W.; Zeiler, W. [TU/e, Univ. of Technology Eindhoven (Netherlands); Brunk, M. [RWTH Aachen (Germany)

2006-07-01

German buildings are often seen as an example to Dutch architects and Dutch building services consultants. Goal of this article is to examine and to understand differences between the Dutch and German top office buildings. Objective is to examine to which extent these buildings were designed intelligently. An Intelligent Building is one that provides a productive cost effective environment through the optimisation of six basic elements; site, skin, systems, structures, services, space plan and staff and the interrelationship between them. Based on these six aspects the comparison is made between Dutch and German buildings. (orig.)

German causative events with placement verbs

Directory of Open Access Journals (Sweden)

De Knop Sabine

2016-06-01

Full Text Available Several studies have described the semantic uses of German posture verbs, but only few have dealt with German placement verbs. The present study wants to make up for this gap. Starting from a collection of examples from the core corpora of the Digitales Wörterbuch der Deutschen Sprache (DWDS and some former studies on posture verbs, it first describes the variety of the most common German placement verbs stellen (‘to put upright’, legen (‘to lay down’, setzen (‘to set’ and stecken (‘to stick’.

The German-Jewish soldier: from participant to victim.

Science.gov (United States)

Penslar, Derek

2011-01-01

The story of German-Jewish soldiers and veterans of World War I illustrates how, under circumstances of inclusion (even if incomplete) rather than vicious persecution, Jewish suffering in wartime, and with it the forms of collective memory and strategies for commemoration of the dead, could closely parallel, even intersect with, the suffering of Germans as a whole. To be sure, the points of intersection were accompanied by points of deflection. Even when Jews served, fought, suffered and died as German soldiers, their interpretations of the war experience, and their communities’ postwar memory and commemorative practices, differed from those of other Germans. In many ways, however, German-Jewish veterans suffered the aftermath of the war as did other Germans; they shared the prevailing fury over war guilt and reparations, and they retained a strong pride in their military service, a pride through which they interpreted the events of 1933–1945.

Learning from the Germans? History and Memory in German and European Discourses of Integration

Directory of Open Access Journals (Sweden)

Andrew Beattie

2007-08-01

Full Text Available History and memory appear to be increasingly important to discussions of European values and identity, as exemplified by references to ‘bitter experiences’ and ‘divided pasts’ in the draft EU constitution. The article takes recent suggestions that Europe could learn from German experiences of confronting multiple difficult pasts as its starting point, and considers critically what lessons those German experiences might in fact hold for ‘Europe’. It explores similarities and differences in the two integration contexts and their dominant approaches to, and assumptions about history and public memory. Specifically, it considers debates about the east-west division of the Cold War and about the place of communism and nazism in public memory. Contrary to common assumptions, the article argues that German experiences are not necessarily worth of European emulation.

GERMANISMS IN THE NORTH ČAKAVIAN DIALECT

Directory of Open Access Journals (Sweden)

Marija Turk

2005-01-01

Full Text Available This paper deals with Germanisms in some local idioms of the North Čakavian dialect. Phonological, morphological and word-formation variants of Germanisms are identified. Special attention is paid to the semantic fields and to the spatial, temporal, functional and stylistic stratification of the Germanisms, and to the degree to which they are recognized and used by speakers who belong to different generations.

Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer.

Science.gov (United States)

Dalva, Monica; El Jellas, Khadija; Steine, Solrun J; Johansson, Bente B; Ringdal, Monika; Torsvik, Janniche; Immervoll, Heike; Hoem, Dag; Laemmerhirt, Felix; Simon, Peter; Lerch, Markus M; Johansson, Stefan; Njølstad, Pål R; Weiss, Frank U; Fjeld, Karianne; Molven, Anders

We have recently described copy number variants (CNVs) of the human carboxyl-ester lipase (CEL) gene, including a recombined deletion allele (CEL-HYB) that is a genetic risk factor for chronic pancreatitis. Associations with pancreatic disease have also been reported for the variable number of tandem repeat (VNTR) region located in CEL exon 11. Here, we examined if CEL CNVs and VNTR length polymorphisms affect the risk for developing pancreatic cancer. CEL CNVs and VNTR were genotyped in a German family with non-alcoholic chronic pancreatitis and pancreatic cancer, in 265 German and 197 Norwegian patients diagnosed with pancreatic adenocarcinoma, and in 882 controls. CNV screening was performed using PCR assays followed by agarose gel electrophoresis whereas VNTR lengths were determined by DNA fragment analysis. The investigated family was CEL-HYB-positive. However, an association of CEL-HYB or a duplication CEL allele with pancreatic cancer was not seen in our two patient cohorts. The frequency of the 23-repeat VNTR allele was borderline significant in Norwegian cases compared to controls (1.2% vs. 0.3%; P = 0.05). For all other VNTR lengths, no statistically significant difference in frequency was observed. Moreover, no association with pancreatic cancer was detected when CEL VNTR lengths were pooled into groups of short, normal or long alleles. We could not demonstrate an association between CEL CNVs and pancreatic cancer. An association is also unlikely for CEL VNTR lengths, although analyses in larger materials are necessary to completely exclude an effect of rare VNTR alleles. Copyright © 2016 IAP and EPC. Published by Elsevier B.V. All rights reserved.

German atomic low meeting 2004

International Nuclear Information System (INIS)

Ossenbuehl, F.

2005-01-01

The conference report on the German atomic law meeting 2004 contains 14 contributions on the German atomic legislation within four parts: Damage precaution in the operational phase; Legal general requirements for the final disposal - considerations ''de lege lata'' and ''de lege ferenda''. Financing of the site searching by a statutory company (''Verbandsmodell''). Atomic supervision authority - federal executive administration or federal self administration?

Immobile Complex Verbs in Germanic

DEFF Research Database (Denmark)

Vikner, Sten

2005-01-01

the V° requirements or the V* requirements. Haider (1993, p. 62) and Koopman (1995), who also discuss such immobile verbs, only account for verbs with two prefix-like parts (e.g., German uraufführen ‘to perform (a play) for the first time' or Dutch herinvoeren ‘to reintroduce'), not for the more...... frequent type with only one prefix-like part (e.g., German bauchreden/Dutch buikspreken ‘to ventriloquize'). This analysis will try to account not only for the data discussed in Haider (1993) and Koopman (1995) but also for the following: - why immobile verbs include verbs with only one prefix-like part...... are immobile, - why such verbs are not found in Germanic VO-languages such as English and Scandinavian....

The German-German history of the nuclear power plant Greifswald. Nuclear power between east and west. 2. ed.

International Nuclear Information System (INIS)

Hoegselius, Per

2015-01-01

The historical study covers the chapters The nuclear power plant Greifswald; Lubmin shortly before the ''Wende'' 1989; the German ''Wende''; from the last vote for the ''Volkskammer (parliament of the German Democratic Republic) to the German reunification; Lubmin in reunified Germany; conclusions and perspectives. In the attachment technical data about the reactors WWER-440/W-230 are summarized, including a list of WWERs in the former eastern bloc countries.

German energy policy in deregulated Europe

International Nuclear Information System (INIS)

Kuhnt, D.

2000-01-01

The author argues in favor of a more fact-oriented German energy policy: Firstly, German energy policy must accept the new European framework of a market economy. This means that German utilities must no longer be burdened with the implementation of political objectives. The German power industry needs a level playing field for competition on a European scale. Consequently, also the European partner countries should not limit themselves to the minimum conditions of the Single Market Directive in opening their markets. Secondly, German energy policy must develop new forms of cooperation with the power industry so as to maintain domestic employment and the addition of value despite considerably stronger competitive pressure. Also the conflicting targets of sustainability, continuity of supply, and economic viability must not only be discussed, but must be turned into productive approaches. Thirdly, this means that there must be no inadmissible solution in matters nuclear. If the German power industry is to remain strong, in the interest of domestic jobs and opportunities for the future, it must not lose any more domestic market share to other European companies. Fourthly, we need a new energy policy which takes cognizance of the results of market development in a more rational, less emotional way. In this respect, it should be limited henceforth to supporting renewable energies and technologies so as to enhance energy efficiency in line with market requirements. Fifthly, German energy policy must not commit the mistake of enforcing deregulation and, at the same time, exempting large segments of the market from competition. Thus, the planned expansion of renewable energies, and the increase in cogeneration to more than thirty percent of the German electricty generation, by way of quotas and revenues for electricity from these sources fed into the public grid, are incompatible with competition in Europe. The electricity tax within the framework of the eco tax, the

[Domestic violence, parenting styles and well-being of German and Turkish juveniles].

Science.gov (United States)

Uslucan, Haci-Halil

2009-01-01

This intercultural comparative study tries to identify the influences of domestic violence and parenting styles on juvenile violence and the well-being of juveniles. To this end, 304 German and 214 Turkish pupils in Berlin at the age of 13 to 16 completed a standardised questionnaire in their schools. The results show that Turkish juveniles report more harsh parenting styles than their German age-mates, but by controlling statistically the educational background of the parents, these differences disappear. Nevertheless, as a stable finding, we can hold that Turkish parents demand from their children a more cultural appropriate and disciplined behaviour. Furthermore, regarding the rates of juvenile violence, the main differences are seen in violence-legitimating attitudes and witnessing parental violence in the Turkish group. Lastly, in the relations between parenting styles and violence, there seems to be no culturally different patterns, but more differences in the intensity of disadvantaging consequences of punishing and harsh parenting on the well-being of juveniles.

A Cultural Comparison of Conflict-Solution Styles Displayed in the Japanese, French, and German School Texts

Science.gov (United States)

Tomo, Rieko

2012-01-01

The purpose of this study is to examine the ways how to solve the conflicts between parents and children by statistical analyses displayed in Japanese, French, and German school texts published in 2000. The results were as follows: (1) Japanese parents and children acting in those texts have much more compromising tendency to avoid conflicts than…

German electric vehicle charging infrastructure: statistically based approach to derive the demand and geographical distribution of charging points

OpenAIRE

González Villafranca, Sara

2013-01-01

Electromobility is widely seen as one of the most promising options to reduce Greenhouse gas emissions in passenger transport. In accordance with the German Government via the National Platform for Electromobility (NPE), an estimated target of 1 million of electric vehicles for 2020 is expected for Germany. One challenge for the widespread development of electric vehicles market is the lack of infrastructure. The great unknowns here are: how many charging stations will be needed in the future...

First epidemiological analysis of breast cancer incidence and tumor characteristics after implementation of population-based digital mammography screening

International Nuclear Information System (INIS)

Weigel, Stefanie; Heindel, Walter; Batzler, W.U.; Decker, T.; Hense, H.W.

2009-01-01

Purpose: to epidemiologically evaluate the impact of digital mammography screening on incidence rates and tumor characteristics for breast cancer. Materials and methods: the first German digital screening units in the clinical routine were evaluated during the implementation period by using data from the cancer registry to compare the incidence rate of breast cancers and prognostic characteristics. 74% of women aged 50-69 within the region of Muenster/Coesfeld/Warendorf were invited between 10/2005 and 12/2007 for initial screening; 55% participated (n = 35961). Results: in 2002-2004 the average breast cancer incidence rate (per 100000) was 297.9. During the implementation of screening, the rate rose to 532.9 in 2007. Of the 349 cancers detected with screening, 76% (265/349) were invasive compared to 90% (546/608) of cases not detected with screening during the same period. 37% (97/265) of cancers detected in the screening program had a diameter of ≤ 10 mm and 75% (198/265) were node-negative compared to 15% (79/546) and 64% (322/503), respectively, in cancers detected outside the screening program. The distribution of invasive tumor size (pT categories) and the nodal status differed with statistical significance between cancers detected in and outside the program (p = 0.005 and p = 0.004, respectively). (orig.)

Cultural differences in postnatal quality of life among German-speaking women - a prospective survey in two countries.

Science.gov (United States)

Grylka-Baeschlin, Susanne; van Teijlingen, Edwin; Gross, Mechthild M

2014-08-15

Assessment of quality of life after childbirth is an important health-outcome measurement for new mothers and is of special interest in midwifery. The Mother-Generated Index (MGI) is a validated instrument to assess postnatal quality of life. The tool has not been applied for making a cross-cultural comparison before. This study investigated (a) responses to the MGI in German-speaking women in Germany and Switzerland; and (b) associations between MGI scores on the one hand and maternity and midwifery care on the other. A two-stage survey was conducted in two rural hospitals 10 km apart, on opposite sides of the German-Swiss border. The questionnaires included the MGI and questions on socio-demographics, physical and mental health and maternity care, and were distributed during the first days after birth and six weeks postpartum. Parametric and non-parametric tests were computed with the statistical programme SPSS. A total of 129 questionnaires were returned an average of three days after birth and 83 in the follow-up after seven weeks. There were no statistically significant differences in the MGI scores between the German and the Swiss women (p = 0.22). Significantly more favourable MGI scores were found associated with more adequate information during pregnancy (p = 0.02), a more satisfactory birth experience (p German-speaking women were higher than those in other studies reported previously. Thus the tool may be able to detect differences in postnatal quality of life among women with substantially divergent cultural backgrounds. Shortcomings in maternity and midwifery care were detected, as for example the inadequate provision of information during pregnancy, a lack of individualised postpartum care during the hospital stay and insufficient support for exclusively breastfeeding mothers. The MGI is an appropriate instrument for maternity care outcome measurement in cross-cultural comparison research.

The German radiation protection standards

International Nuclear Information System (INIS)

Becker, Klaus; Neider, Rudolf

1977-01-01

The German Standards Institute (DIN Deutsches Institut fuer Normung, Berlin) is engaged in health physics standards development in the following committees. The Nuclear Standards Committee (NKe), which deals mainly with nuclear science and technology, the fuel cycle, and radiation protection techniques. The Radiology Standards Committee (FNR), whose responsibilities are traditionally the principles of radiation protection and dosimetry, applied medical dosimetry, and medical health physics. The German Electrotechnical Commission (DKE), which is concerned mostly with instrumentation standards. The Material Testing Committee (FNM), which is responsible for radiation protection in nonmedical radiography. The current body of over one hundred standards and draft standards was established to supplement the Federal German radiation protection legislation, because voluntary standards can deal in more detail with the specific practical problems. The number of standards is steadily expanding due to the vigorous efforts of about thirty working groups, consisting of essentially all leading German experts of this field. Work is supported by the industry and the Federal Government. A review of the present status and future plans, and of the international aspects with regard to European and world (ISO, etc.) standards will be presented

Dictionary for veterinary science and biosciences. German-English/English-German. With trilingual appendix: Latin terms

International Nuclear Information System (INIS)

Mack, R.

1988-01-01

This dictionary has been compiled as a result of many years experience of translating German texts in the biological sciences, particularly veterinary medicine. The author's aim is to supplement the standard German-English general dictionaries with technical terms to in the fields of anatomy, microbiology, physiology, parasitology, pathology, pharmacology, toxicology and zootechny, with special reference to domestic animals and their diseases. (orig.) [de

Cancer mortality risk of nuclear power workers due to the exposure of ionising radiation in Germany

International Nuclear Information System (INIS)

Fehringer, F.; Seitz, G.; Hammer, G.P.; Blettner, M.

2006-01-01

A cohort study of German nuclear power workers was set up to investigate overall and cancer mortality risk related to a chronic exposure to ionising radiation of low-level dose. The German study was performed as a part of an international study carried out by the International Agency for Research on Cancer (IARC), Lyon. First results of the international study have been published recently [1]. German data are not yet included in this analysis. The German cohort consists of 4844 employees from 10 nuclear power plants. All persons who worked in these nuclear power plants in 1991 or started employment between 1991 und 1997 are included (except for employees of one plant, whose observation period started in 1992). These persons accumulated about 31,000 person years. Overall, 68 deaths were observed in the observation period between 1.1.1991-31.12.1997. Standardized mortality ratios (SMR) were computed for all causes of death, all cancers, cardiovascular diseases, external causes, and all other causes. Overall, a strong healthy worker effect was observed (SMR=0.52 [95% CI: 0.41;0.67]). No increase in total cancer mortality was seen (SMR=0.85 [95% CI: 0.53;1.30]). However, numbers are too small for stable risk estimates and further effort is under way to complete the cohort in terms of power plants and to extend the follow-up until 2005. (authors)

Cancer mortality risk of nuclear power workers due to the exposure of ionising radiation in Germany

Energy Technology Data Exchange (ETDEWEB)

Fehringer, F.; Seitz, G. [Berufsgenossenschaft der Feinmechanik und Elektrotechnik, Koln (Germany); Hammer, G.P.; Blettner, M. [Johannes Gutenberg-Universitat Mainz, Institut fur Medizinische Biometrie, Epidemiologie und Informatik des Klinikums (Germany)

2006-07-01

A cohort study of German nuclear power workers was set up to investigate overall and cancer mortality risk related to a chronic exposure to ionising radiation of low-level dose. The German study was performed as a part of an international study carried out by the International Agency for Research on Cancer (IARC), Lyon. First results of the international study have been published recently [1]. German data are not yet included in this analysis. The German cohort consists of 4844 employees from 10 nuclear power plants. All persons who worked in these nuclear power plants in 1991 or started employment between 1991 und 1997 are included (except for employees of one plant, whose observation period started in 1992). These persons accumulated about 31,000 person years. Overall, 68 deaths were observed in the observation period between 1.1.1991-31.12.1997. Standardized mortality ratios (SMR) were computed for all causes of death, all cancers, cardiovascular diseases, external causes, and all other causes. Overall, a strong healthy worker effect was observed (SMR=0.52 [95% CI: 0.41;0.67]). No increase in total cancer mortality was seen (SMR=0.85 [95% CI: 0.53;1.30]). However, numbers are too small for stable risk estimates and further effort is under way to complete the cohort in terms of power plants and to extend the follow-up until 2005. (authors)

Statistical methods for assays with limits of detection: Serum bile acid as a differentiator between patients with normal colons, adenomas, and colorectal cancer

Directory of Open Access Journals (Sweden)

Bonnie LaFleur

2011-01-01

Full Text Available In analytic chemistry a detection limit (DL is the lowest measurable amount of an analyte that can be distinguished from a blank; many biomedical measurement technologies exhibit this property. From a statistical perspective, these data present inferential challenges because instead of precise measures, one only has information that the value is somewhere between 0 and the DL (below detection limit, BDL. Substitution of BDL values, with 0 or the DL can lead to biased parameter estimates and a loss of statistical power. Statistical methods that make adjustments when dealing with these types of data, often called left-censored data, are available in many commercial statistical packages. Despite this availability, the use of these methods is still not widespread in biomedical literature. We have reviewed the statistical approaches of dealing with BDL values, and used simulations to examine the performance of the commonly used substitution methods and the most widely available statistical methods. We have illustrated these methods using a study undertaken at the Vanderbilt-Ingram Cancer Center, to examine the serum bile acid levels in patients with colorectal cancer and adenoma. We have found that the modern methods for BDL values identify disease-related differences that are often missed, with statistically naive approaches.

The German Birth Order Register - order-specific data generated from perinatal statistics and statistics on out-of-hospital births 2001-2008

OpenAIRE

Michaela Kreyenfeld; Rembrandt D. Scholz; Frederik Peters; Ines Wlosnewski

2010-01-01

Until 2008, Germany’s vital statistics did not include information on the biological order of each birth. This resulted in a dearth of important demographic indicators, such as the mean age at first birth and the level of childlessness. Researchers have tried to fill this gap by generating order-specific birth rates from survey data, and by combining survey data with vital statistics. This paper takes a different approach by using hospital statistics on births to generate birth order-specific...

German Grammar in the Students' Words: The "Essentialization" of German Grammar by American College-Level Learners

Science.gov (United States)

Chavez, Monika

2011-01-01

This study of 134 college-level learners of German, enrolled in four years of instruction, showed them to "essentialize" German grammar when asked to describe it to a hypothetical friend. Kubota defined the term essentialization to capture learners' views of the target culture. Its main characteristic is the presupposition of "essential, stable,…

Changes in autopsy rates among cancer patients and their impact on cancer statistics from a public health point of view: a longitudinal study from 1980 to 2010 with data from Cancer Registry Zurich.

Science.gov (United States)

Bieri, Uwe; Moch, Holger; Dehler, Silvia; Korol, Dimitri; Rohrmann, Sabine

2015-06-01

During the last decades, autopsy rates have dramatically decreased in many countries. The Cancer Registry Zurich, which exists since 1980, provides the opportunity to address to what extent the number of autopsies in cancer patients has changed over a longer period of time and how often autopsies provide a diagnosis of clinically undetected cancer. Data from the Cancer Registry Zurich consisting of 102,434 cancer cases among 89,933 deceased patients between 1980 and 2010 were analyzed by means of descriptive statistics. The autopsy rate declined from 60 % in 1980 to 7 % in 2010. The total number of autopsies performed decreased from 1179 in 1986 to 220 in 2010. Furthermore, there was also a decline in the rate of newly detected tumours based on autopsy information. In 1980, the rate of newly detected tumours through autopsy was 42 % compared with 2010, when the rate had declined to 17 %. A consequence of the reduced autopsy rate is the reduction of incidental findings at autopsy in cancer registration. However, this reduction has not negatively affected the total incidence of cancer. It seems that the state-of-the-art diagnostic tools used for tumour detection are sufficiently reliable, allowing the scientific community to trust the quality of data provided by cancer registries in spite of decreasing autopsy rates.

Reforms in German Higher Education: Implementing and Adapting Anglo-American Organizational and Management Structures at German Universities

Science.gov (United States)

Liefner, Ingo; Schatzl, Ludwig; Schroder, Thomas

2004-01-01

Currently, the German higher education system is undergoing drastic reform. Competitive structures and funding mechanisms are being introduced that are already successfully used in other countries. However, critics state that cultural differences prevent the effective application, in German universities, of funding mechanisms and incentives…

A German format for pupils’ training

CERN Multimedia

Antonella Del Rosso

2012-01-01

Every year CERN welcomes thousands of pupils from schools worldwide for a half-day visit to the Laboratory. However, since 2011 about ten selected students from Germany have been given the opportunity to experience CERN in much greater depth. They are fully sponsored by the German Ministry of Education and supported by an organising structure at TU Dresden - the Dresden University of Technology - led by Michael Kobel. It’s an investment that's paying off in Germany.   The German teachers who participated in the “Netzwerk Teilchenwelt” project, at CERN last week. “Netzwerk Teilchenwelt” is a project that involves 23 German universities, the DESY Laboratory, several schools and, of course, CERN. Launched in 2010 with a contribution from the German Ministry for Science and Research of about 1 million euros over three years, the project has so far involved over 4,000 students and 500 teachers. “Thanks to this project, both pupils...

Development of LiDAR measurements for the German offshore test site

International Nuclear Information System (INIS)

Rettenmeier, A; Kuehn, M; Waechter, M; Rahm, S; Mellinghoff, H; Siegmeier, B; Reeder, L

2008-01-01

The paper introduces the content of the recently started joint research project 'Development of LiDAR measurements for the German Offshore Test Site' which has the objective to support other research projects at the German offshore test site 'alpha ventus'. The project has started before the erection of the offshore wind farm and one aim is to give recommendations concerning LiDAR technology useable for offshore measurement campaigns and data analysis. The work is organized in four work packages. The work package LiDAR technology deals with the specification, acquisition and calibration of a commercial LiDAR system for the measurement campaigns. Power curve measurements are dedicated to power curve assessment with ground-based LiDAR using standard statistical methods. Additionally, it deals with the development of new methods for the measurement of non-steady short-term power curves. Wind field research aims at the development of wake loading simulation methods of wind turbines and the exploration of loading control strategies and nacelle-based wind field measurement techniques. Finally, dissemination of results to the industry takes place in work package Technology transfer

Validation of the German version of the insomnia severity index in adolescents, young adults and adult workers: results from three cross-sectional studies.

Science.gov (United States)

Gerber, Markus; Lang, Christin; Lemola, Sakari; Colledge, Flora; Kalak, Nadeem; Holsboer-Trachsler, Edith; Pühse, Uwe; Brand, Serge

2016-05-31

A variety of objective and subjective methods exist to assess insomnia. The Insomnia Severity Index (ISI) was developed to provide a brief self-report instrument useful to assess people's perception of sleep complaints. The ISI was developed in English, and has been translated into several languages including German. Surprisingly, the psychometric properties of the German version have not been evaluated, although the ISI is often used with German-speaking populations. The psychometric properties of the ISI are tested in three independent samples: 1475 adolescents, 862 university students, and 533 police and emergency response service officers. In all three studies, participants provide information about insomnia (ISI), sleep quality (Pittsburgh Sleep Quality Index), and psychological functioning (diverse instruments). Descriptive statistics, gender differences, homogeneity and internal consistency, convergent validity, and factorial validity (including measurement invariance across genders) are examined in each sample. The findings show that the German version of the ISI has generally acceptable psychometric properties and sufficient concurrent validity. Confirmatory factor analyses show that a 1-factor solution achieves good model fit. Furthermore, measurement invariance across gender is supported in all three samples. While the ISI has been widely used in German-speaking countries, this study is the first to provide empirical evidence that the German version of this instrument has good psychometric properties and satisfactory convergent and factorial validity across various age groups and both men and women. Thus, the German version of the ISI can be recommended as a brief screening measure in German-speaking populations.

Mortality of German travellers on passenger vessels.

Science.gov (United States)

Oldenburg, Marcus; Herzog, Jan; Püschel, Klaus; Harth, Volker

2016-01-01

In the past two decades, more and more Germans decided to spend their holidays on a passenger vessel. This study examined the frequencies and causes of deaths of German travellers aboard passenger vessels of all flags. The shipboard deaths of all German travellers within the time period from 1998 to 2008 were counted using the German civil central register in Berlin. The available documentation in this register provides information on frequencies, circumstances and causes of deaths on ships. In the above-mentioned period of time, the total cohort of German travellers on cruise ships is estimated to be 5.97 million persons. During the 11-year examination period, 135 shipboard deaths of German passengers [102 males (75.6%) and 33 females (24.4%)] were recorded. Out of these travellers, 110 died on cruise ships. When considering only the passengers on cruise ships (without those on ferries) an average crude mortality rate of 1.8 per 100,000 German passengers was calculated. The crude mortality rate of shipboard death for males and females was 2.5 and 0.8 per 100,000 German passengers with a mean age of 71.2 years [standard deviation (SD) 16.0 years] and 73.3 years (SD 16.0 years), respectively. Significantly, more deceased travellers older than 70 years were observed on traditional cruise ships and resort vessels than on passenger ferries (P = 0.001). The causes of death were documented in 85 cases (63.0%). Out of these documented deaths, 82 (96.5%) cases were regarded to be natural causes (particularly circulatory diseases) and 3 (3.5%) as unnatural causes (twice drowning and once an accidental fall). In spite of the large proportion of unknown causes of death, this study argues for a high significance of internal causes of deaths among German passengers. Thus, ship's doctors-particularly those on traditional cruise ships-should be well experienced in internal and geriatric medicines. © The Author 2016. Published by Oxford University Press on behalf of

Skin care practice in German nursing homes: a German-wide cross-sectional study.

Science.gov (United States)

Kottner, Jan; Rahn, Yasmin; Blume-Peytavi, Ulrike; Lahmann, Nils

2013-04-01

Due to anatomical and physiological changes in the course of aging and due to increased vulnerability, there are special skin care needs in elderly and care-dependent persons. Little is known about skin care practice in German long-term care facilities. The aim of the study was to gather epidemiological data about skin care practice in German nursing homes. In spring 2012 a German-wide cross sectional study was conducted in 47 nursing homes. Based on standardized data collection sheets. demographics and variables about methods and frequencies of skin cleansing and application of skin care products for 3 552 nursing home residents were collected and analyzed. The variables age, gender and level of care dependency was representative for the group of all German nursing home residents. More than 90% of investigated nursing home residents required skin care assistance. Washing body parts or the whole body were conducted most frequently (89.1%, 95% CI 88.0- 90.1). Skin care leave-on products were used in 91.7% (95% CI 90.7-92.6), whereas there were large variations between individuals. In total, more than 100 brands were used. Skin care practice in multimorbid care dependent persons shows large variations. How skin care products meet the special requirements of aged skin and whether they enhance the skin barrier function and prevent cuteneous skin damage is unknown. © The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.

Sustainable Civil-Society Engagement: Potentials of a Transnational Civil Society in French-German, Polish-German, and Czech-German Border Regions

Directory of Open Access Journals (Sweden)

Klaus Boehnke

2015-04-01

Full Text Available Based on representative survey data, the present study examines potentials for the sustainable development of a transnational civil society in French-German, Polish-German, and Czech-German border regions. The theoretical framework is a social capital approach in the tradition of Putnam. Transnational engagement is seen as a key element for the development of a border-crossing civil society. For the analysis, existing forms of social capital were classified according to their bridging and bonding functions and the potentials of local and transnational activities are described. Furthermore, using multilevel analysis, the predictive power of different variables like individual dispositions and specific contexts of the regions on cross-border activities are examined. Descriptively, the expected lower level of local civil-society engagement, in general, and also with regard to the transnational activities was found for post-socialist border regions. It is shown that, first and foremost, existing experience in civil-society engagement in the local context is a high-impact predictor for both transnational activities and an interest in such activities. Other variables like feelings of a historical burden or the economic situation of the region are less important.

The Dividend Policy of German Firms

NARCIS (Netherlands)

Andres, C.; Betzer, A.; Goergen, M.; Renneboog, L.D.R.

2008-01-01

Abstract: German firms pay out a lower proportion of their cash flows, but a higher proportion of their published profits than UK and US firms. We estimate partial adjustment models and report two major findings. First, German firms base their dividend decisions on cash flows rather than published

The Dividend Policy of German Firms

NARCIS (Netherlands)

Andres, C.; Betzer, A.; Goergen, M.; Renneboog, L.D.R.

2008-01-01

German firms pay out a lower proportion of their cash flows, but a higher proportion of their published profits than UK and US firms. We estimate partial adjustment models and report two major findings. First, German firms base their dividend decisions on cash flows rather than published earnings as

Fifty years of German nuclear legislation

International Nuclear Information System (INIS)

Heller, W.

2006-01-01

The political situation and the state of legislation after World War II make it difficult to pinpoint a precise date of origin of German nuclear legislation. The restrictions imposed by the Allied High Commission (AHC) without any exception put a ban on the production of uranium and thorium metal as well as the construction of nuclear reactors. These restrictions were lifted expressly when the German Atomic Energy Act (AtG) entered into force on January 1, 1960, i.e. much later than the formal step of gaining sovereignty, which was marked by the protocol of May 5, 1955 terminating the Occupation Statute. In October 1955, the German federal government established the then Federal Ministry for Atomic Matters also in an attempt to reconnect to developments in nuclear fission in other parts of the Western world. To supersede the AHC law, the German federal government in December 1956 publicized a draft Atomic Energy Act. It is safe, therefore, to consider that year the starting point of German atomic legislation. This step was followed by deliberations preparatory to the adoption of the Atomic Energy Act. In 1957, however, adoption failed because no two-thirds majority was reached to amend the Basic Law, i.e. the Constitution. As a consequence, some federal states saw the need to adopt state legislation to regulate this area. On December 3, 1959, a new draft Atomic Energy Act was adopted by the German federal parliament after the second and third readings - coupled with an amendment to the Basic Law on that same day - with the votes of the opposition and with one abstention. (orig.)

Bayesian versus frequentist statistical inference for investigating a one-off cancer cluster reported to a health department

Directory of Open Access Journals (Sweden)

Wills Rachael A

2009-05-01

Full Text Available Abstract Background The problem of silent multiple comparisons is one of the most difficult statistical problems faced by scientists. It is a particular problem for investigating a one-off cancer cluster reported to a health department because any one of hundreds, or possibly thousands, of neighbourhoods, schools, or workplaces could have reported a cluster, which could have been for any one of several types of cancer or any one of several time periods. Methods This paper contrasts the frequentist approach with a Bayesian approach for dealing with silent multiple comparisons in the context of a one-off cluster reported to a health department. Two published cluster investigations were re-analysed using the Dunn-Sidak method to adjust frequentist p-values and confidence intervals for silent multiple comparisons. Bayesian methods were based on the Gamma distribution. Results Bayesian analysis with non-informative priors produced results similar to the frequentist analysis, and suggested that both clusters represented a statistical excess. In the frequentist framework, the statistical significance of both clusters was extremely sensitive to the number of silent multiple comparisons, which can only ever be a subjective "guesstimate". The Bayesian approach is also subjective: whether there is an apparent statistical excess depends on the specified prior. Conclusion In cluster investigations, the frequentist approach is just as subjective as the Bayesian approach, but the Bayesian approach is less ambitious in that it treats the analysis as a synthesis of data and personal judgements (possibly poor ones, rather than objective reality. Bayesian analysis is (arguably a useful tool to support complicated decision-making, because it makes the uncertainty associated with silent multiple comparisons explicit.

Media response to colon cancer campaigns in Switzerland 2005-2007: regional newspapers are the most reliable among the printed media

Directory of Open Access Journals (Sweden)

Borisch Bettina

2010-06-01

Full Text Available Abstract Background Health campaigns are frequently covered by printed media, but coverage is not homogeneous across different types of newspapers. Switzerland as a multilinguistic country with many newspapers offers a good field for study. A better understanding of how printed media report on national campaigns against colon cancer in the three main linguistic regions may help to improve future public health interventions. Therefore, we analyzed articles published between 2005 and 2007 during the campaigns "Darmkrebs-nie?" and "Self-Care" in the German, French and Italian regions of Switzerland. Findings Some 65% of articles reporting on colon cancer were in German, 23% and 12% were in French and Italian respectively. During the campaign, topics linked to colon cancer were increasingly covered by the media. Regional newspapers (66% reported significantly more about colon cancer and produced the most detailed articles. Both gain- and loss-framed messages have been used by journalists, whereas the campaigns used merely gain-framed messages. Latin (French and Italian newspapers mixed gain- and loss-framed messages in the same articles, while German articles mainly used a single frame throughout. Conclusions Swiss-German papers reported more about the topic and the reporting was quantitatively and qualitatively more prominent in regional papers. The press followed the campaigns closely only during the period of campaigning, with high coverage. We propose to consider the regional press as an important vehicle of health information. Moreover, slight differences in framing can be observed between German and Latin articles.

Cancer incidence in the environment of nuclear power plants

International Nuclear Information System (INIS)

Heller, W.

2008-01-01

An epidemiological study of cancer in children in the environment of nuclear power plants has been written on behalf of the German Federal Ministry for the Environment, Nature Conservation, and Nuclear Safety (BMU) and the Federal Office for Radiation Protection (BfS). The study is a case controlled study based on the German Register of Cancer in Children. The most important outcome of the study is the finding that a connection can be observed in Germany between the proximity to a nuclear power plant of the place of living and the risk of a child to develop cancer in the 5 th year of life. The magnitude of this risk was calculated to be approximately 0.2%, i.e., out of a total of 13,373 cases of cancer, 29 would be attributable to living within the 5 km zone around a nuclear power plant. This finding demands an explanation. The study proper cannot serve as a material witness because it had not been designed to establish cause and effect relations between the risk and potential origins. The expert consultants frankly state that current knowledge about radiation biology and epidemiology in principle does not allow the ionizing radiation emitted by German nuclear power plants in normal operation to be interpreted as the cause. Whether confounders, selection or chance play a role in the observed and documented finding cannot be explained for good by the study. However, although representing an honorable acquittal, the study produces a different effect in the public mind. What is remembered is the link between nuclear power plants and cancer in children. (orig.)

Operational Art and the German 1918 Offensives

OpenAIRE

Zabecki, D T

2009-01-01

At the tactical level of war the Germans are widely regarded as having had the most innovative and proficient army of World War I. Likewise, many historians would agree that the Germans suffered from serious, if not fatal, shortcomings at the strategic level of war. It is at the middle level of warfare, the operational level, that the Germans seem to be the most difficult to evaluate. Although the operational was only fully accepted in the 1980s by many Western militaries as...

High-Speed Maglev Trains; German Safety Requirements

Science.gov (United States)

1991-12-31

This document is a translation of technology-specific safety requirements developed : for the German Transrapid Maglev technology. These requirements were developed by a : working group composed of representatives of German Federal Railways (DB), Tes...

The Danish Press during the German Occupation

DEFF Research Database (Denmark)

Roslyng-Jensen, Palle

2010-01-01

Censorship, self-censorship in Danish newspapers and Danish Radio during the German occupation of Denmark 1940-45......Censorship, self-censorship in Danish newspapers and Danish Radio during the German occupation of Denmark 1940-45...

Cancer of the gallbladder—Chilean statistics

Science.gov (United States)

Villanueva Olivares, Luis

2016-01-01

Chile has the world’s highest rate of incidence as well as death from cancer of the gallbladder and biliary ducts. The problem is most acute in the southern provinces. These areas constitute the low average income associated with low educational attainment and a high rate of obesity compared with the rest of Chile. We could also include genetic factors related to processes of lithogenesis to these elements which are more common among the Mapuche. This population sub-group could benefit from special government programmes for early diagnosis and treatment of lithiasic disease and for the management of risk factors such as obesity. In this way, we could reduce the mortality rate of gallbladder cancer. PMID:28105075

Cancer of the gallbladder-Chilean statistics.

Science.gov (United States)

Villanueva, Luis

2016-01-01

Chile has the world's highest rate of incidence as well as death from cancer of the gallbladder and biliary ducts. The problem is most acute in the southern provinces. These areas constitute the low average income associated with low educational attainment and a high rate of obesity compared with the rest of Chile. We could also include genetic factors related to processes of lithogenesis to these elements which are more common among the Mapuche. This population sub-group could benefit from special government programmes for early diagnosis and treatment of lithiasic disease and for the management of risk factors such as obesity. In this way, we could reduce the mortality rate of gallbladder cancer.

Strongly enhanced colorectal cancer risk stratification by combining family history and genetic risk score

Directory of Open Access Journals (Sweden)

Weigl K

2018-01-01

Full Text Available Korbinian Weigl,1,2 Jenny Chang-Claude,3,4 Phillip Knebel,5 Li Hsu,6 Michael Hoffmeister,1 Hermann Brenner1,2,7 1Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ, Heidelberg, 2German Cancer Consortium (DKTK, German Cancer Research Center (DKFZ, Heidelberg, 3Unit of Genetic Epidemiology, German Cancer Research Center (DKFZ, Heidelberg, 4University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, 5Department for General, Visceral and Transplantation Surgery, University Heidelberg, Heidelberg, Germany; 6Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; 7Division of Preventive Oncology, German Cancer Research Center (DKFZ and National Center for Tumor Diseases (NCT, Heidelberg, Germany Background and aim: Family history (FH and genetic risk scores (GRSs are increasingly used for risk stratification for colorectal cancer (CRC screening. However, they were mostly considered alternatively rather than jointly. The aim of this study was to assess the potential of individual and joint risk stratification for CRC by FH and GRS.Patients and methods: A GRS was built based on the number of risk alleles in 53 previously identified single-nucleotide polymorphisms among 2,363 patients with a first diagnosis of CRC and 2,198 controls in DACHS [colorectal cancer: chances for prevention through screening], a population-based case-control study in Germany. Associations between GRS and FH with CRC risk were quantified by multiple logistic regression.Results: A total of 316 cases (13.4% and 214 controls (9.7% had a first-degree relative (FDR with CRC (adjusted odds ratio [aOR] 1.86, 95% CI 1.52–2.29. A GRS in the highest decile was associated with a 3.0-fold increased risk of CRC (aOR 3.00, 95% CI 2.24–4.02 compared with the lowest decile. This association was tentatively more pronounced in older age groups. FH and GRS were essentially unrelated, and their

The perception of the fehmarnbelt connection among german stakeholders

DEFF Research Database (Denmark)

Lohse, Sandrina; Jespersen, Per Homann

This report gives an overview of the planned improvements of the German hinterland infrastructure connected to the fixed Fehmarn Belt Link (FBL), as well as the views of the key German stake holders towards the FBL.......This report gives an overview of the planned improvements of the German hinterland infrastructure connected to the fixed Fehmarn Belt Link (FBL), as well as the views of the key German stake holders towards the FBL....

Teaching German Culture: An Alternative Approach.

Science.gov (United States)

Ray, Maruta L.

1985-01-01

Describes a college course on German culture in which the criterion for the inclusion of any topic in the syllabus is its mention--preferably recurrent--in the German press. Additional emphasis is placed upon the historical background of the current events. Classes are a combination of films, lectures, discussions, and student reports. (SED)

Improving Critical Thinking and Authenticity in Testing Business German

DEFF Research Database (Denmark)

Egbert, Maria; Maxim, Hiram

1998-01-01

in Business German, the Priifung Wirtschaftsdmtsch Intmnational [International Business German Examination] (PWD) and the Zertijikat I)mtschfur den Bmuf [German Cer- tificate for Professional Purposes] (ZDfB), test only students' information retrieval skills and fail to assess their critical thinking...

German concept and status of the disposal of spent fuel elements from German research reactors

International Nuclear Information System (INIS)

Komorowski, K.; Storch, S.; Thamm, G.

1995-01-01

Eight research reactors with a power ≥ 100 kW are currently being operated in the Federal Republic of Germany. These comprise three TRIGA-type reactors (power 100 kW to 250 kW), four swimming-pool reactors (power 1 MW to 10 MW) and one DIDO type reactor (power 23 MW). The German research reactors are used for neutron scattering for basic research in the field of solid state research, neutron metrology, for the fabrication of isotopes and for neutron activation analysis for medicine and biology, for investigating the influence of radiation on materials and for nuclear fuel behavior. It will be vital to continue current investigations in the future. Further operation of the German research reactors is therefore indispensable. Safe, regular disposal of the irradiated fuel elements arising now and in future operation is of primary importance. Furthermore, there are several plants with considerable quantities of spent fuel, the safe disposal of which is a matter of urgency. These include above all the VKTA facilities in Rossendorf and also the TRIGA reactors, where disposal will only be necessary upon decommissioning. The present paper report is concerned with the disposal of fuel from the German research reactors. It briefly deals with the situation in the USA since the end of 1988, describes interim solutions for current disposal requirements and then mainly concentrates on the German disposal concept currently being prepared. This concept initially envisages the long-term (25--50 years) dry interim storage of fuel elements in special containers in a central German interim store with subsequent direct final disposal without reprocessing of the irradiated fuel

Statistical study on cancer patients of Korea cancer centre hospital

Energy Technology Data Exchange (ETDEWEB)

Choi, Soo Yong; Kim, Kee Hwa; Mok, Kang Sung [Korea Cancer Center Hospital of Korea Atomic Energy Research Institute, Seoul (Korea, Republic of)

1994-12-01

The total number of malignant neoplasms included in this study 53,566 cases(14.1%) among 379,582 patients from 1984 to 1993. On sex, females with 51.3% were much more than males with 48.7%. The highest proportion of cancer patients by age was 35.0% in males and 28.4% in females, respectively for 50-59 age group. The most frequent primary site among males was found to be stomach with 33.2%, followed by liver(15.1%), lung(14.9%), esophagus(5.3%) and larynx(3.3%). In females, the first order was uterine cervix with 37.8%, followed by stomach(16.5%), breast(14.8%), thyroid gland(4.3%) and lung (3.8%). The proportion of malignant neoplasms diagnosed by histology made up 67.0%, whereas 20.2% was diagnosed by clinical investigation(X-ray, CT, MRI etc). Among the cancer patients initially diagnosed in this hospital, the proportion of malignant neoplasms by the extent of disease was 3.7% for patient with carcinoma-in-situ, 58.7% for patients with localized involvement, 18.4% for patients with regional involvement and 11.1% for patients with distant involvement. Among the cancer patients initially treatment in this hospital, the proportion of malignant neoplasms by the method of treatment was 27.5% for surgery, 22.5% for radiotherapy and 30.1% for chemotherapy. The proportion of cancer patients traced to death was only to 3.6%, 1,944 cases. Among them, 72.5% survived for less than 1 year. 17 figs, 7 tabs, 28 refs. (Author).

Statistical study on cancer patients of Korea cancer centre hospital

International Nuclear Information System (INIS)

Choi, Soo Yong; Kim, Kee Hwa; Kang Sung Mok

1994-12-01

The total number of malignant neoplasms included in this study 53,566 cases(14.1%) among 379,582 patients from 1984 to 1993. On sex, females with 51.3% were much more than males with 48.7%. The highest proportion of cancer patients by age was 35.0% in males and 28.4% in females, respectively for 50-59 age group. The most frequent primary site among males was found to be stomach with 33.2%, followed by liver(15.1%), lung(14.9%), esophagus(5.3%) and larynx(3.3%). In females, the first order was uterine cervix with 37.8%, followed by stomach(16.5%), breast(14.8%), thyroid gland(4.3%) and lung (3.8%). The proportion of malignant neoplasms diagnosed by histology made up 67.0%, whereas 20.2% was diagnosed by clinical investigation(X-ray, CT, MRI etc). Among the cancer patients initially diagnosed in this hospital, the proportion of malignant neoplasms by the extent of disease was 3.7% for patient with carcinoma-in-situ, 58.7% for patients with localized involvement, 18.4% for patients with regional involvement and 11.1% for patients with distant involvement. Among the cancer patients initially treatment in this hospital, the proportion of malignant neoplasms by the method of treatment was 27.5% for surgery, 22.5% for radiotherapy and 30.1% for chemotherapy. The proportion of cancer patients traced to death was only to 3.6%, 1,944 cases. Among them, 72.5% survived for less than 1 year. 17 figs, 7 tabs, 28 refs. (Author)

German standard and German X-ray guide lines as a guide for quality assurance in X-ray diagnosis

International Nuclear Information System (INIS)

Pychlau, P.

1985-01-01

The German standard DIN 6868 (in preparation) and parts of the German X-ray Ordinance of 1973 deal with quality assurance in X-ray diagnosis. It is shown that both documents support each other and are a guidance for daily work. (author)

["Maintaining a Common Culture"--the German Research Foundation and the Austrian-German scientific aid in the interbellum].

Science.gov (United States)

Fengler, Silke; Luxbacher, Günther

2011-12-01

After the end of the Great War, private as well as public research funding in Austria was anaemic and slow to develop. Whereas the German state-funded Deutsche Forschungsgemeinschaft (DFG) was established as early as 1920, first steps in that direction were only taken in Austria in the late 1920s. In 1929, the Osterreichisch-deutsche Wissenschaftshilfe (ODW) was founded under the auspices of the Austrian Academy of Sciences and the DFG. Although prima facie on an equal footing, the new research funding organisation was in fact highly dependent on its German cooperation partner. The article explores for the first time ODW's position within the German and Austrian science and foreign policies, which aimed to promote the idea of unification of both states within the German Reich. A quantitative analysis of the subsidies policy in the first five years of existence shows that the ODW gave financial aid primarily to conservative research fields, affecting the intellectual balance of power in the First Austrian Republic. Policy continuities and discontinuities of the organisation in the course of the national-socialist rise to power in Germany after 1933 are examined in the second part of the article. The article thus both increases our knowledge about the most important German research funding organisation DFG, and identifies some of the fundamental structural features of Austrian science policy in the interwar years.

Surficial geology and benthic habitat of the German Bank seabed, Scotian Shelf, Canada

Science.gov (United States)

Todd, Brian J.; Kostylev, Vladimir E.

2011-01-01

To provide the scientific context for management of a newly opened scallop fishing ground, surficial geology and benthic habitats were mapped on German Bank on the southern Scotian Shelf off Atlantic Canada. To provide a seamless regional dataset, multibeam sonar surveys covered 5320 sqaure kilometres of the bank in water depths of 30–250 m and provided 5 m horizontal resolution bathymetry and backscatter strength. Geoscience data included high-resolution geophysical profiles (seismic reflection and sidescan sonar) and seabed sediment samples. Geological interpretation and is overlain in places by glacial and postglacial sediment. Biological data included seafloor video transects and photographs from which 127 taxa of visible megabenthos were identified. Trawl bycatch data were obtained from government annual research surveys. Statistical analysis of revealed that bedrock is exposed at the seafloor on much of German Bankthese two datasets and a suite of oceanographic environmental variables demonstrated that significantly different fauna exist on bedrock, glacial sediment and postglacial sediment.

Crossing the Lexicon: Anglicisms in the German Hip Hop Community

Science.gov (United States)

Garley, Matthew E.

2012-01-01

The influence of English on German has been an ongoing subject of intense popular and academic interest in the German sphere. In order to better understand this language contact situation, this research project investigates anglicisms--instances of English language material in a German language context--in the German hip hop community, where the…

Verb Movement Variation in Germanic and Optimality Theory

DEFF Research Database (Denmark)

Vikner, Sten

2001-01-01

This habilitation dissertation falls into two parts. In the first part, "Establishing the typology: Verb Movement in the Germanic VO- and OV-languages", I continue the work in Vikner (1995a, 1997) on the movement of finite verbs across the Germanic languages. Chapter 1 argues that rich finite inf...... data are treated: constructions with auxiliaries, negation and/or do-insertion, and chapter 7 accounts for the differences in distribution between the V2 word order and the non-V2 word order between the languages.......This habilitation dissertation falls into two parts. In the first part, "Establishing the typology: Verb Movement in the Germanic VO- and OV-languages", I continue the work in Vikner (1995a, 1997) on the movement of finite verbs across the Germanic languages. Chapter 1 argues that rich finite...... inflection triggers V°-to-I° movement in the Germanic (and Romance) VO-languages, chapter 2 supports the claim that Yiddish is an OV-language, and chapter 3 defends the view that all Germanic OV-languages except Yiddish do not have V°-to-I° movement. Where Part I tries to establish facts and arguments which...

Organization of the German nuclear industry

International Nuclear Information System (INIS)

Anon.

1992-01-01

Corporate ownership within the German nuclear industry has evolved constantly during the last decade, and recent acquisitions and mergers, reunification of the country, as well as preparation for a unified European power market, have led to many significant changes during the past two years. The country's nuclear industry continues to struggle under an increasingly anti-nuclear political environment, yet nuclear power provided more than one-third of Germany's total electricity generation in 1991. As in many countries, particularly in western Europe, many German companies involved in different facets of the nuclear industry are interrelated. Usually as a means of horizontal or vertical integration, the country's nuclear utilities own, directly or indirectly, shares in uranium mining projects; conversion, enrichment, and fabrication companies; or other utilities' nuclear power plants. The utilities own partial interests in companies in supporting industries as well, including transportation firms, waste management companies, uranium broker/traders, and nuclear equipment manufacturers. While the majority of the companies owned are German, numerous investments are made in non-German firms also

Posttraumatic stress disorder (PTSD) in the German Armed Forces: a retrospective study in inpatients of a German army hospital

OpenAIRE

Bandelow, Borwin; Koch, Manuel; Zimmermann, Peter; Biesold, Karl-Heinz; Wedekind, Dirk; Falkai, Peter

2012-01-01

In 2006 and 2007, around 0.4 and 0.7% of all German soldiers involved in missions abroad were registered as suffering from PTSD. The frequency of PTSD in the German Armed Forces was assessed from army records. All soldiers admitted to the German Military Hospital in Hamburg, Germany, with PTSD (n = 117) in the years 2006 and 2007 were assessed by using questionnaires and structure interviews. Risk factors associated with PTSD were identified. Of the 117 soldiers with PTSD, 39.3% were in missi...

German science and black racism--roots of the Nazi Holocaust.

Science.gov (United States)

Haas, François

2008-02-01

The Nazi's cornerstone precept of "racial hygiene" gave birth to their policy of "racial cleansing" that led to the murders of millions. It was developed by German physicians and scientists in the late 19th century and is rooted in the period's Social Darwinism that placed blacks at the bottom of the racial ladder. This program was first manifested in the near-extermination of the African Herero people during the German colonial period. After WWI, the fear among the German populace that occupying African troops and their Afro-German children would lead to "bastardization" of the German people formed a unifying racial principle that the Nazis exploited. They extended this mind-set to a variety of "unworthy" groups, leading to the physician-administered racial Nuremberg laws, the Sterilization laws, the secret sterilization of Afro-Germans, and the German euthanasia program. This culminated in the extermination camps.

Interviewing German scientists on climate change. A preliminary study

Energy Technology Data Exchange (ETDEWEB)

Ungar, S. [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Kuestenforschung; Toronto Univ., Scarborough (Canada)

2004-07-01

This study is based on in-depth interviews with 25 German scientists at the Coastal Research Institute of the GKSS-Forschungszentrum. It takes as its context the differential rhetoric and planning on climate change found in Germany and North America. The interviews try to throw light on the early German decision to address climate change, and to assess the current attitudes, beliefs and experiences of these German scientists. The results reveal a degree of complacency among these scientists, including a sense that Germany is not particularly threatened by climate change and has the capacity to adapt to it. The scientists are critical of inaction among the German population, but themselves uphold a ''light version'' of the precautionary principle. They have great difficulty translating the idea of climate change into popular metaphors that can be grasped by children. They strongly reject any link between German leadership on the issue as a result of a sense of guilt about the German past. (orig.)

The French-German initiative for Chernobyl. Programme 3 study of the health effects

International Nuclear Information System (INIS)

Becker, S.; Kellerer, A.; Pott-Born, R.; Gagniere, B.; Mansoux, H.; Rutschkowsky, N.; Valenty, M.; Calmont, I.; Brun-Yaba, Ch.; Verger, P.; Franc, B.; Robert-Gnansia, E.; Briend, A.

2006-03-01

The results of the French-German Initiative Health Effects project, conducted over a period of four years, were presented to the international authorities at a congress held in October 2004 in Kiev and are summarised below. Thyroid cancer increase in children and young adults seems clearly related to exposure at young ages in 1986. For the other cancers sites, the observed results do not add any decisive elements that would make it possible to quantify the impact of post-Chernobyl irradiation: the trend observed in time is similar in both exposed and non-exposed areas in most situations. These observations do not exclude the fact that an increase of leukaemia may exist for those exposed as children; it may be too low to be detectable in a statistically significant way. Similarly, the higher rate of congenital malformations observed during recent years cannot be attributed to radiation, because the same trend over time is observed both in contaminated and non-contaminated areas in Belarus. Reliable and up-to-date knowledge has been collected in a H.E.D.A.C. database, it should facilitate communication concerning the health impact of the Chernobyl accident. The main results published at national or international level, will be made available to the public and the international scientific community via modern distribution methods and will contribute to the development of a necessary cohesion between international research programmes and work carried out locally. Contact the web site: www.fgi.icc.gov.ua For detailed information, final reports are available: contact with mentioned investigators is proposed (see authors of final reports) or contact scientific coordinator M. Tirmarche at I.R.S.N. (France) D. Bazyka at R.C.R.M., Kiev in charge of the database and communication of scientific results at Chernobyl Center

The French-German initiative for Chernobyl. Programme 3 study of the health effects

Energy Technology Data Exchange (ETDEWEB)

Becker, S.; Kellerer, A.; Pott-Born, R. [Munich Univ., Radiobiological Institute (Germany); Gagniere, B. [CIRE Ouest, 35 - Rennes (France); Mansoux, H.; Rutschkowsky, N.; Valenty, M.; Calmont, I.; Brun-Yaba, Ch. [Institut de Radioprotection et de Surete Nucleaire, 92 - Fontenay-aux-Roses (France); Verger, P. [ORS PACA, 13 - Marseille (France); Franc, B. [Hopital Ambroise-Pare, 92 - Boulogne (France); Robert-Gnansia, E. [European Instituteof Genomutations, 69 - Lyon (France); Briend, A. [Scientific and Technical Institute of Nutrition and Alimentation/CNAM, 75 - Paris (France)

2006-03-15

The results of the French-German Initiative Health Effects project, conducted over a period of four years, were presented to the international authorities at a congress held in October 2004 in Kiev and are summarised below. Thyroid cancer increase in children and young adults seems clearly related to exposure at young ages in 1986. For the other cancers sites, the observed results do not add any decisive elements that would make it possible to quantify the impact of post-Chernobyl irradiation: the trend observed in time is similar in both exposed and non-exposed areas in most situations. These observations do not exclude the fact that an increase of leukaemia may exist for those exposed as children; it may be too low to be detectable in a statistically significant way. Similarly, the higher rate of congenital malformations observed during recent years cannot be attributed to radiation, because the same trend over time is observed both in contaminated and non-contaminated areas in Belarus. Reliable and up-to-date knowledge has been collected in a H.E.D.A.C. database, it should facilitate communication concerning the health impact of the Chernobyl accident. The main results published at national or international level, will be made available to the public and the international scientific community via modern distribution methods and will contribute to the development of a necessary cohesion between international research programmes and work carried out locally. Contact the web site: www.fgi.icc.gov.ua For detailed information, final reports are available: contact with mentioned investigators is proposed (see authors of final reports) or contact scientific coordinator M. Tirmarche at I.R.S.N. (France) D. Bazyka at R.C.R.M., Kiev in charge of the database and communication of scientific results at Chernobyl Center.

A 'German world' shared among doctors: a history of the relationship between Japanese and German psychiatry before World War II.

Science.gov (United States)

Hashimoto, Akira

2013-06-01

This article deals with the critical history of German and Japanese psychiatrists who dreamed of a 'German world' that would cross borders. It analyses their discourse, not only by looking at their biographical backgrounds, but also by examining them in a wider context linked to German academic predominance and cultural propaganda before World War II. By focusing on Wilhelm Stieda, Wilhelm Weygandt and Kure Shuzo, the article shows that the positive evaluation of Japanese psychiatry by the two Germans encouraged Kure, who was eager to modernize the treatment of and institutions for the mentally ill in Japan. Their statements on Japanese psychiatry reflect their ideological and historical framework, with reference to national/ethnic identity, academic position, and the relationship between Germany and Japan.

[German ophthalmologists and NSDAP

Science.gov (United States)

Rohrbach, Jens Martin

2008-01-01

Approximately 40-45 % of all German physicians joined the National Socialist German Workers Party (NSDAP) until 1945. Reasons for party membership are manifold and still a matter of debate. Very likely, the extraordinary high representation of medical doctors in the NSDAP was rather a result of active entry than recruitment by the party. There are only few data concerning the willingness of ophthalmologists to become a party member ("Parteigenosse", "Pg"). According to the list of University teachers in Germany ("Hochschullehrerkarte"; Federal Archive, Berlin), the list of the members of the German Ophthalmological Society (DOG) of 1934 and especially the list of NSDAP-members (Federal Archive, Berlin) the following conclusions can be drawn: 1. Directors of German University eye hospitals (chairmen) were members of the NSDAP with a frequency of 23% in 1933 and 48% in 1938 as well as in 1943. The motivation for joining the party was most likely the perspective of acceleration of the academic career. 2. "Only" 30% of the ophthalmologists working in private praxis were "Pg" (until 1945). 3. Both chairmen and ophthalmologists in private praxis were equally hindered to join the NSDAP between May 1st 1933 and May 1st 1937 when the party temporarily stopped registration. 4. The majority of ophthalmologists who joined the NSDAP were born between 1880 and 1900 and thus had taken part in World War I as soldiers or had experienced the times of need after WW I. Only few ophthalmologists succeeded in the NS-hierarchy and probably only one ophthalmologist, Walther Löhlein from Berlin, came in personal contact with Adolf Hitler who was constantly in fear for his sight after his eye injury in October 1918. The "Law for the prevention of genetically disabled offsprings" ("Gesetz zur Verhütung erbkranken Nachwuchses") from July 14th, 1933 separated ophthalmologists into two parties: those advocating sterilization to a high degree and those recommending sterilization only

Marking over 50 years of Franco-German understanding

CERN Multimedia

Corinne Pralavorio

2013-01-01

To mark the 50th anniversary of the Elysée Treaty between France and Germany, which established a basis for cooperation between the two countries in order to set the seal on a lasting peace, secondary school pupils came to CERN to research the Franco-German relationship.   Beneath the Microcosm Garden bubble chamber, Robert Jacob describes the BEBC project to secondary school students from the Pays de Gex and their German exchange partners. On 22 January 1963, German Chancellor Konrad Adenauer and French President Charles de Gaulle signed the Elysée Treaty. This treaty of friendship cemented the partnership between the two countries, which had torn each other apart over the course of several devastating wars. Fifty years on, secondary school students from the Pays de Gex and their German exchange partners have been learning about Franco-German friendship. How was the partnership between the two countries built? Who were its architects? These questions brought them to C...

The German Adaptation and Standardization of the Personality Assessment Inventory (PAI).

Science.gov (United States)

Groves, Julia A; Engel, Rolf R

2007-02-01

We developed the German Adaptation of the Personality Assessment Inventory (PAI; Morey, 1991) under careful consideration of current adaptation literature and guidelines. The adaptation process included the translation of the 344 items into German, a back translation into English as well as the testing of the language equivalence using a bilingual sample. We then standardized the final German version of the PAI for the German population. We compared the American and German norm and reliability data. The observed differences in PAI scale means did not exceed 5 T scores. Internal consistency reliability showed a similar pattern in both language versions, although the German alpha coefficients were on average slightly lower than the American ones. Factor structure was similar in both versions. We discuss expectations about the German PAI and possible problems for its practical usefulness for the German-speaking population.

Compilation of accident statistics in PSE

International Nuclear Information System (INIS)

Jobst, C.

1983-04-01

The objective of the investigations on transportation carried out within the framework of the 'Project - Studies on Safety in Waste Management (PSE II)' is the determination of the risk of accidents in the transportation of radioactive materials by rail. The fault tree analysis is used for the determination of risks in the transportation system. This method offers a possibility for the determination of frequency and consequences of accidents which could lead to an unintended release of radionuclides. The study presented compiles all data obtained from the accident statistics of the Federal German Railways. (orig./RB) [de

The German Program and International Education: A Comprehensive Model.

Science.gov (United States)

McConeghy, Patrick M.

1990-01-01

Argues for a comprehensive approach toward teaching German as a second language in response to students' needs to acquire a global perspective. Rather than stressing only syntax, grammar, and vocabulary, German language education should also attempt to teach sensitivity to, knowledge of, and insight into German culture. (JL)

Coursebook of German: Gender Aspect

OpenAIRE

Aleksandra Valeryevna Filippova

2015-01-01

The present article regards Aspekte 1 coursebook of German as a foreign language in the context of the gender policy initiated at the end of the last century by sociolinguists and by the representatives of the so called feminist criticism of the German language. This policy has been carried out up to date, and, according to many sociological and linguistic research, it is aimed at destructing gender stereotypes in teaching and reference materials. The use of this policy is conditioned by the ...

Massive job cuts threaten East German science

CERN Multimedia

Hamer, M

1990-01-01

German reunification could result in thousands of scientists losing their jobs. At the end of this year the East German state budget for science will run out. Scientists in the East are keen to find Western support to protect their research (1 page).

Evaluation of the Quality of Online Information for Patients with Rare Cancers: Thyroid Cancer.

Science.gov (United States)

Kuenzel, Ulrike; Monga Sindeu, Tabea; Schroth, Sarah; Huebner, Jutta; Herth, Natalie

2017-01-24

The Internet offers an easy and quick access to a vast amount of patient information. However, several studies point to the poor quality of many websites and the resulting hazards of false information. The aim of this study was to assess quality of information on thyroid cancer. A patients' search for information about thyroid cancer on German websites was simulated using the search engine Google and the patient portal "Patienten-Information.de". The websites were assessed using a standardized instrument with formal and content aspects from the German Cancer Society. Supporting the results of prior studies that analysed patient information on the Internet, the data showed that the quality of patient information on thyroid cancer is highly heterogeneous depending on the website providers. The majority of website providers are represented by media and health providers other than health insurances, practices and professionals offering patient information of relatively poor quality. Moreover, most websites offer patient information of low-quality content. Only a few trustworthy, high-quality websites exist. Especially Google, a common search engine, focuses more on the dissemination of information than on quality aspects. In order to improve the patient information from the Internet, the visibility of high-quality websites must be improved. For that, education programs to improve patients' eHealth literacy are needed. A quick and easy evaluation tool for online information suited for patients should be implemented, and patients should be taught to integrate such a tool into their research process.

German General Staff Officer Education and Current Challenges

National Research Council Canada - National Science Library

Groeters, Thomas

2006-01-01

"German General Staff Officer Education and Current Challenges" examines the institutional education of German General Staff Officers, as experienced by the author, and offers a "Conceptual Competency...

Football fever: goal distributions and non-Gaussian statistics

Science.gov (United States)

Bittner, E.; Nußbaumer, A.; Janke, W.; Weigel, M.

2009-02-01

Analyzing football score data with statistical techniques, we investigate how the not purely random, but highly co-operative nature of the game is reflected in averaged properties such as the probability distributions of scored goals for the home and away teams. As it turns out, especially the tails of the distributions are not well described by the Poissonian or binomial model resulting from the assumption of uncorrelated random events. Instead, a good effective description of the data is provided by less basic distributions such as the negative binomial one or the probability densities of extreme value statistics. To understand this behavior from a microscopical point of view, however, no waiting time problem or extremal process need be invoked. Instead, modifying the Bernoulli random process underlying the Poissonian model to include a simple component of self-affirmation seems to describe the data surprisingly well and allows to understand the observed deviation from Gaussian statistics. The phenomenological distributions used before can be understood as special cases within this framework. We analyzed historical football score data from many leagues in Europe as well as from international tournaments, including data from all past tournaments of the “FIFA World Cup” series, and found the proposed models to be applicable rather universally. In particular, here we analyze the results of the German women’s premier football league and consider the two separate German men’s premier leagues in the East and West during the cold war times as well as the unified league after 1990 to see how scoring in football and the component of self-affirmation depend on cultural and political circumstances.

Current state of the art, multimodality research and future visions for the treatment of patients with prostate cancer: consensus results from "Challenges and Chances in Prostate Cancer Research Meeting 2013".

Science.gov (United States)

Combs, Stephanie E; Debus, Jürgen; Feick, Günter; Hadaschik, Boris; Hohenfellner, Markus; Schüle, Roland; Zacharias, Jens-Peter; Schwardt, Malte

2014-11-04

A brainstorming and consensus meeting organized by the German Cancer Aid focused on modern treatment of prostate cancer and promising innovative techniques and research areas. Besides optimization of screening algorithms, molecular-based stratification and individually tailored treatment regimens will be the future of multimodal prostate cancer management. Effective interdisciplinary structures, including biobanking and data collection mechanisms are the basis for such developments.

Deutsch im Louvre (oder: Deutsch als tote Sprache) (German in the Louvre [or, German as a Dead Language])

Science.gov (United States)

Markwald, Sabine

1976-01-01

Describes a German course for archeologists and art historians, given in the Louvre by the Paris Goethe Institute. Reliance is placed on the students' visual memory, with schematic presentation of pronoun and article declension. This approach sometimes fosters errors and misunderstandings. The verb system is emphasized. (Text is in German.)…

DIMA – Annotation guidelines for German intonation

DEFF Research Database (Denmark)

Kügler, Frank; Smolibocki, Bernadett; Arnold, Denis

2015-01-01

This paper presents newly developed guidelines for prosodic annotation of German as a consensus system agreed upon by German intonologists. The DIMA system is rooted in the framework of autosegmental-metrical phonology. One important goal of the consensus is to make exchanging data between groups...

Franco-German initiative for Chernobylsk health project; Initiative Franco-Allemande pour Tchernobyl projet sante

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

The works led within the framework of the French-German initiative ( I.F.A.) on the health of the populations exposed to the ionizing radiations concentrated on the main useful indicators of health for the study of the excess incidence of cancers after a relatively long latency period. No net difference of the tendencies of leukaemia incidence was revealing between exposed regions and not exposed regions of Ukraine, Belarus and Russia. As regards solid tumors, the rates of incidence presented the same tendencies of increase in the course of time whatever are the studied regions. On the other hand, the works showed a net increase of the rate of incidence of the thyroid cancers in the exposed regions, notably at the aged persons of less than ten years at the time of the accident. In Belarus, the national register of cancers allowed to bring to light a very high number of thyroid cancers, from the beginning 1990 at the children of less than 15 years and net increase of these cancers, since 1998, in the slice of 15/29 the years. So for this exposed population, the risk of thyroid cancer continues to express itself 20 years after the accident. Besides, no tangible difference from the point of view of the tendencies between exposed and not exposed regions was revealing for the congenital malformations. (N.C.)

Occupational exposure and mortality in the German uranium miner cohort

International Nuclear Information System (INIS)

Schnelzer, M.; Dufey, F.; Grosche, B.; Sogl, M.; Tschense, A.; Walsh, L.; Kreuzer, M.

2014-01-01

The German uranium miners cohort study comprises 58,982 men employed in the GDR by the Wismut company for at least six months between 1946 and 1989. Particularly in the early years, miners were exposed to high levels of radon, silica and other harmful substances. The aim of the cohort study is to investigate the health effects of occupational exposures. The cohort was established in 1998 with mortality follow-ups every five years, i.e. vital status and cause of death are ascertained. Annual exposures to radon progeny, external gamma-radiation, long-lived radionuclides, fine dust, silica and arsenic dust were individually assessed by means of a comprehensive job-exposure matrix. For data analyses Poisson regression models were used. By end of 2008, 25,438 (43 %) cohort members were deceased with known cause of death in 94 %. In total 7,780 cancer mortalities were observed, including 3,500 from lung cancer. Lung cancer mortality is twice as high as in the general population largely due to occupational radon progeny and silica exposure. Also 975 silicosis deaths were observed and there is some evidence for a relationship between radon progeny exposure and cancers of the extra-thoracic airways. Circulatory diseases and non-malignant diseases of the airways were also investigated, but no relationship to occupational exposure was found. Up to now health effects of uranium mining in the Wismut cohort primarily manifest themselves as increases in lung cancer and silicosis mortality due to high radon progeny and silica exposure. With increasing duration of follow-up, further findings regarding more rare causes of death and levels of exposure relevant today are expected.

Out of the German parliament into the German Museum?

International Nuclear Information System (INIS)

Lieb, E.

1989-01-01

It is currently discussed whether the German Bundestag can deal with the interdepartmental problems of technology assessment with the Commissions of Inquiry on the one hand and whether it has adequate instruments available with the department-related standing Bundestag committees in order to deal with technology assessment. In its report the Commission of Inquiry for Technology Assessment of the past legislative period came to the conclusion that the US parliamentary advisory model which has been realized with OTA could, of course, not be transferred to the situation of the German Bundestag without hesitation, but that the Bundestag should also have a permanent scientific department staff with a sufficient number of personnel and material. The congress was to offer the possibility to discuss the problems of technology assessment with regard to this up-to-date background with experts and members of parliament of the various commissions of inquiry and commissions of the Bundestag which were summoned in order to judge essential technologies and also to solve the problem of the institutionalization of technology assessment. (orig./DG) [de

NONINVASIVE DIAGNOSIS OF BLADDER CANCER BY CROSS-POLARIZATION OPTICAL COHERENCE TOMOGRAPHY: A BLIND STATISTICAL STUDY

Directory of Open Access Journals (Sweden)

O. S. Streltsova

2014-07-01

Full Text Available Whether cross-polarization (CP optical coherence tomography (OCT could be used to detect early bladder cancer was ascertained; it was compared with traditional OCT within the framework of blind (closed clinical statistical studies. One hundred and sixteen patients with local nonexophytic (flat pathological processes of the bladder were examined; 360 CP OCT images were obtained and analyzed. The study used an OCT 1300-U CP optical coherence tomographer. CP OCT showed a high (94% sensitivity and a high (84% specificity in the identification of suspected nonexophytic areas in the urinary bladder.

Extraction of UMLS® Concepts Using Apache cTAKES™ for German Language.

Science.gov (United States)

Becker, Matthias; Böckmann, Britta

2016-01-01

Automatic information extraction of medical concepts and classification with semantic standards from medical reports is useful for standardization and for clinical research. This paper presents an approach for an UMLS concept extraction with a customized natural language processing pipeline for German clinical notes using Apache cTAKES. The objectives are, to test the natural language processing tool for German language if it is suitable to identify UMLS concepts and map these with SNOMED-CT. The German UMLS database and German OpenNLP models extended the natural language processing pipeline, so the pipeline can normalize to domain ontologies such as SNOMED-CT using the German concepts. For testing, the ShARe/CLEF eHealth 2013 training dataset translated into German was used. The implemented algorithms are tested with a set of 199 German reports, obtaining a result of average 0.36 F1 measure without German stemming, pre- and post-processing of the reports.

Measuring prostate-specific quality of life in prostate cancer patients scheduled for radiotherapy or radical prostatectomy and reference men in Germany and Canada using the Patient Oriented Prostate Utility Scale-Psychometric (PORPUS-P

Directory of Open Access Journals (Sweden)

Kuechler Thomas

2009-08-01

Full Text Available Abstract Background The PORPUS-P is a short questionnaire for measuring prostate-specific quality of life (QoL, which was designed in Canada for use in prostate cancer (PC patients. We aimed to generate a German version and compare PORPUS-P scores of German reference men from the general population, and German and Canadian patients with newly diagnosed PC who were scheduled to receive radical prostatectomy (RP or radiotherapy (RT. Methods The study sample consisted of 988 reference men, 121 German and 66 Canadian PC patients scheduled for RT, and 371 German and 68 Canadian PC patients scheduled for RP. All men completed the PORPUS-P (German postal questionnaire, Canada personal interview. Data were gathered from PC patients before the start of therapy. Results Canadian patients were better educated than the German patients, and fewer were retired. Patients scheduled to receive RT were older and more were retired. German RT patients had lower D'Amico risk scores and pre-treatment Gleason scores than RP patients, and Canadian RT patients had higher pre-treatment PSA than RP patients. Urinary and sexual dysfunction were seen in PC patients (especially RT patients, but were also common in the German reference men. Crude mean PORPUS-P scores differed statistically significant between German RT and RP and Canadian RP and RT patients, with RT patients having higher QoL scores. The differences in age-adjusted mean PORPUS-P scores between reference men and RP patients were not clinically significant, while RT patients had (clinically significantly lower scores than the reference men. Conclusion The German translation of the PORPUS-P appears to be a short and feasible tool for assessing prostate-specific QoL. Although we found a similar response pattern, Canadian and German PC patients scheduled to receive RT or RP rated their pre-treatment quality of life on different levels, which reveals the need for national reference data. Problems in several Qo

Clinical translation and regulatory aspects of CAR/TCR-based adoptive cell therapies-the German Cancer Consortium approach.

Science.gov (United States)

Krackhardt, Angela M; Anliker, Brigitte; Hildebrandt, Martin; Bachmann, Michael; Eichmüller, Stefan B; Nettelbeck, Dirk M; Renner, Matthias; Uharek, Lutz; Willimsky, Gerald; Schmitt, Michael; Wels, Winfried S; Schüssler-Lenz, Martina

2018-04-01

Adoptive transfer of T cells genetically modified by TCRs or CARs represents a highly attractive novel therapeutic strategy to treat malignant diseases. Various approaches for the development of such gene therapy medicinal products (GTMPs) have been initiated by scientists in recent years. To date, however, the number of clinical trials commenced in Germany and Europe is still low. Several hurdles may contribute to the delay in clinical translation of these therapeutic innovations including the significant complexity of manufacture and non-clinical testing of these novel medicinal products, the limited knowledge about the intricate regulatory requirements of the academic developers as well as limitations of funds for clinical testing. A suitable good manufacturing practice (GMP) environment is a key prerequisite and platform for the development, validation, and manufacture of such cell-based therapies, but may also represent a bottleneck for clinical translation. The German Cancer Consortium (DKTK) and the Paul-Ehrlich-Institut (PEI) have initiated joint efforts of researchers and regulators to facilitate and advance early phase, academia-driven clinical trials. Starting with a workshop held in 2016, stakeholders from academia and regulatory authorities in Germany have entered into continuing discussions on a diversity of scientific, manufacturing, and regulatory aspects, as well as the benefits and risks of clinical application of CAR/TCR-based cell therapies. This review summarizes the current state of discussions of this cooperative approach providing a basis for further policy-making and suitable modification of processes.

The Great War and German Memory

DEFF Research Database (Denmark)

Leese, Peter

2012-01-01

Review essay on Jason Crouthamel, The Great War and German Memory. Society, Politics and Psychological Trauma, 1914-18 (2009) and Anton Kaes, Shell Shock Cinema: Weimar Culture and the Wounds of War (2009)......Review essay on Jason Crouthamel, The Great War and German Memory. Society, Politics and Psychological Trauma, 1914-18 (2009) and Anton Kaes, Shell Shock Cinema: Weimar Culture and the Wounds of War (2009)...

Assessment of accident risks from german nuclear plants

International Nuclear Information System (INIS)

Heuser, F.W.

1979-01-01

The German risk study are presented. The main objectives can be summed up as follows: (a) An assessment of the societal risk due to accidents in nuclear power plants with reference to German conditions; (b) To get experience in the field of risk analysis and to provide a basis for estimation of uncertainties; (c) To provide guidance for future activities in the German Reactor Safety Research Program. Finally several conclusions reached by this study are discussed. (author)

Sibling Rivalry in Educational Attainment: The German Case

OpenAIRE

Ira N. Gang; Thomas Bauer

2000-01-01

Recent studies exploring sibling rivalry in the allocation of household resources in the U.S. produce conflicting results. We contribute to this discussion by addressing the role of sibling rivalry in educational attainment in Germany. Using the German Socioeconomic Panel (GSOEP) we are able to distinguish how the effects of sibling rivalry vary by cultural affiliation, i.e., among families of West German, East German and foreign origin. We also point out and correct for a reference group pro...

Gender differences in depression scores of Iranian and german medical students.

Science.gov (United States)

Ahmadi, Jamshid; Ahmadi, Nahid; Soltani, Fereshteh; Bayat, Fatemeh

2014-01-01

The aim was to evaluate gender differences in depression scores of Iranian and German medical students. Two hundred Iranian medical students (100 men and 100 women) and 200 German medical students (100 men and 100 women) were selected randomly and completed the English form of the self-rating Beck Depression Inventory (BDI). Analysis gave a mean rating of 10.7 ± 6.6 for Iranian men and 10.9 ± 7.81 for Iranian women (NS). Also, 5 ± 4.9 for German men and 5.6 ± 5.0 for German women (NS). On Item 2, which asked whether the person was pessimistic 33% of Iranian men and 30% of Iranian women indicated that they were pessimistic (NS). Also, 21% of German men and 20% of German women indicated that they were pessimistic (NS). On Item 9, which asked about suicidal tendencies, 9% of Iranian men and 13% of Iranian women reported as having suicidal tendencies (NS). Also, 13% of German men and 21% of German women reported as having self-harming thoughts (NS). The present study showed no gender differences in Iranian and German medical students' scores on the BDI.

Systematic skin cancer screening in Northern Germany.

Science.gov (United States)

Breitbart, Eckhard W; Waldmann, Annika; Nolte, Sandra; Capellaro, Marcus; Greinert, Ruediger; Volkmer, Beate; Katalinic, Alexander

2012-02-01

The incidence of skin cancer is increasing worldwide. For decades, opportunistic melanoma screening has been carried out to respond to this burden. However, despite potential positive effects such as reduced morbidity and mortality, there is still a lack of evidence for feasibility and effectiveness of organized skin cancer screening. The main aim of the project was to evaluate the feasibility of systematic skin cancer screening. In 2003, the Association of Dermatological Prevention was contracted to implement the population-based SCREEN project (Skin Cancer Research to Provide Evidence for Effectiveness of Screening in Northern Germany) in the German state of Schleswig-Holstein. A two-step program addressing malignant melanoma and nonmelanocytic skin cancer was implemented. Citizens (aged ≥ 20 years) with statutory health insurance were eligible for a standardized whole-body examination during the 12-month study period. Cancer registry and mortality data were used to assess first effects. Of 1.88 million eligible citizens, 360,288 participated in SCREEN. The overall population-based participation rate was 19%. A total of 3103 malignant skin tumors were found. On the population level, invasive melanoma incidence increased by 34% during SCREEN. Five years after SCREEN a substantial decrease in melanoma mortality was seen (men: observed 0.79/100,000 and expected 2.00/100,000; women: observed 0.66/100,000 and expected 1.30/100,000). Because of political reasons (resistance as well as lack of support from major German health care stakeholders), it was not possible to conduct a randomized controlled trial. The project showed that large-scale systematic skin cancer screening is feasible and has the potential to reduce skin cancer burden, including mortality. Based on the results of SCREEN, a national statutory skin cancer early detection program was implemented in Germany in 2008. Copyright © 2010 American Academy of Dermatology, Inc. Published by Mosby, Inc. All

Lexical Reading in Dysfluent Readers of German

Science.gov (United States)

Gangl, Melanie; Moll, Kristina; Jones, Manon W.; Banfi, Chiara; Schulte-Körne, Gerd; Landerl, Karin

2018-01-01

Dyslexia in consistent orthographies like German is characterized by dysfluent reading, which is often assumed to result from failure to build up an orthographic lexicon and overreliance on decoding. However, earlier evidence indicates effects of lexical processing at least in some German dyslexic readers. We investigated variations in reading…

Self-rated treatment outcomes in medical rehabilitation among German and non-German nationals residing in Germany: an exploratory cross-sectional study.

Science.gov (United States)

Brzoska, P; Sauzet, O; Yilmaz-Aslan, Y; Widera, T; Razum, O

2016-03-28

In many European countries, foreign nationals experience, on average, less favorable treatment outcomes in rehabilitative care than the respective majority population. In Germany, this for example is reflected in a lower occupational performance and a higher risk of disability retirement after rehabilitation as analyses of routine data show. However, little is known about the perspective of health care users. The aim of the present study was to compare self-rated treatment outcomes between German and non-German nationals undergoing in-patient medical rehabilitation in Germany. We analyzed data from a cross-sectional representative rehabilitation patient survey of 239,811 patients from 642 clinics in Germany who completed about 3 weeks of in-patient rehabilitative treatment. The self-rating of the treatment outcome was based on a dichotomized Likert scale consisting of three items. A multilevel logistic regression analysis adjusted for various demographic, socio-economic, health and other covariates was conducted to examine differences in the self-rated treatment outcome between German and non-German nationals. Of the 239,811 respondents 0.9% were nationals from Turkey, 0.8% had a nationality from a former Yugoslavian country, 0.9% held a nationality from the South European countries Portugal, Spain, Italy or Greece and 1.9% were nationals from other countries. Non-German nationals reported a less favorable self-rated outcome than Germans. Adjusted odds ratios [OR] for reporting a less favorable treatment outcome were 1.24 (95%-confidence interval [95%-CI]: 1.12-1.37) for nationals from the South European countries Portugal/Spain/Italy/Greece, 1.62 (95%-CI: 1.45-1.80) for Turkish nationals and 1.68 (95%-CI: 1.52-1.85) for nationals from Former Yugoslavia. Knowledge on health outcomes from the patients' point of view is important for the provision of patient-centered health care. Our study showed that non-German nationals report less favorable outcomes of

German and Ukrainian Phonological Isomorphs. Typology: Germanic and Slavic Languages. German-Ukraine-Slavic Contrasting Correspondence Vocabulary

Science.gov (United States)

Petryshyn, Ivan

2016-01-01

The works of many scholars on Germanic and Slavic Languages do not really try to contrast the two biggest Indo-European language families, but analyse them seperately, as any close comparison seem to be unconvincible. In many works, we find some parts that usually would deal with loan words/borrowings/barbarisms. And, yet, we noticed that there…

Assisted reproductive techniques and the risk of anorectal malformations: a German case-control study.

Science.gov (United States)

Zwink, Nadine; Jenetzky, Ekkehart; Schmiedeke, Eberhard; Schmidt, Dominik; Märzheuser, Stefanie; Grasshoff-Derr, Sabine; Holland-Cunz, Stefan; Weih, Sandra; Hosie, Stuart; Reifferscheid, Peter; Ameis, Helen; Kujath, Christina; Rissmann, Anke; Obermayr, Florian; Schwarzer, Nicole; Bartels, Enrika; Reutter, Heiko; Brenner, Hermann

2012-09-15

The use of assisted reproductive techniques (ART) for treatment of infertility is increasing rapidly worldwide. However, various health effects have been reported including a higher risk of congenital malformations. Therefore, we assessed the risk of anorectal malformations (ARM) after in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Data of the German Network for Congenital Uro-REctal malformations (CURE-Net) were compared to nationwide data of the German IVF register and the Federal Statistical Office (DESTATIS). Odds ratios (95% confidence intervals) were determined to quantify associations using multivariable logistic regression accounting for potential confounding or interaction by plurality of births. In total, 295 ARM patients born between 1997 and 2011 in Germany, who were recruited through participating pediatric surgeries from all over Germany and the German self-help organisation SoMA, were included. Controls were all German live-births (n = 10,069,986) born between 1997 and 2010. Overall, 30 cases (10%) and 129,982 controls (1%) were born after IVF or ICSI, which translates to an odds ratio (95% confidence interval) of 8.7 (5.9-12.6) between ART and ARM in bivariate analyses. Separate analyses showed a significantly increased risk for ARM after IVF (OR, 10.9; 95% CI, 6.2-19.0; P risk for ARM among children born after ART. Elevations of risk were seen after both IVF and ICSI. Further, separate analyses of patients with isolated ARM, ARM with associated anomalies and those with a VATER/VACTERL association showed increased risks in each group. An increased risk of ARM was also seen among both singletons and multiple births.

Satisfaction with rehabilitative health care services among German and non-German nationals residing in Germany: a cross-sectional study.

Science.gov (United States)

Brzoska, Patrick; Sauzet, Odile; Yilmaz-Aslan, Yüce; Widera, Teresia; Razum, Oliver

2017-08-11

Rehabilitation following medical conditions is largely offered as in-patient service in Germany. Foreign-national residents use rehabilitative services less often than Germans and attain less favourable treatment outcomes. These differences are independent of demographic, socioeconomic and health characteristics. Satisfaction with different aspects of rehabilitative care presumably affects the effectiveness of rehabilitative services. We compared the degree of satisfaction with different domains of the rehabilitative care process between Germans and non-German nationals residing in Germany. We used data from a cross-sectional rehabilitation patient survey annually conducted by the German Statutory Pension Insurance Scheme. The sample comprises 274 513 individuals undergoing medical rehabilitation in 642 hospitals during the years 2007-2011. Participants rated their satisfaction with different domains of rehabilitation on multi-item scales. We dichotomised each scale to low/moderate and high satisfaction. For each domain, a multilevel adjusted logistic regression analysis was conducted to examine differences in the levels of satisfaction between German and non-German nationals. Average marginal effects (AMEs) and 99.5% CI were computed as effect estimates. AMEs represent differences in the probability for the occurrence of the outcome. Turkish nationals had a higher probability for being less satisfied with most aspects of their rehabilitation, with AMEs ranging between 0.05 (99.5% CI 0.00 to 0.09) for 'satisfaction with psychological care' and 0.11 (99.5% CI 0.08 to 0.14) for 'satisfaction with treatments during rehabilitation'. Patients from former Yugoslavia and from Portugal/Spain/Italy/Greece were as satisfied as Germans with most aspects of their rehabilitation. Turkish nationals are less satisfied with their rehabilitative care than other population groups. This may be attributable to the diversity of the population in terms of its expectations towards

Understanding Cancer Prognosis

Medline Plus

Full Text Available ... Contact Dictionary Search About Cancer Causes and Prevention Risk Factors Genetics Cancer Prevention Overview Research Cancer Screening Cancer ... Is Cancer Cancer Statistics Cancer Disparities Causes & Prevention Risk Factors Genetics Cancer Prevention Overview Screening Cancer Screening Overview ...

P-MartCancer-Interactive Online Software to Enable Analysis of Shotgun Cancer Proteomic Datasets.

Science.gov (United States)

Webb-Robertson, Bobbie-Jo M; Bramer, Lisa M; Jensen, Jeffrey L; Kobold, Markus A; Stratton, Kelly G; White, Amanda M; Rodland, Karin D

2017-11-01

P-MartCancer is an interactive web-based software environment that enables statistical analyses of peptide or protein data, quantitated from mass spectrometry-based global proteomics experiments, without requiring in-depth knowledge of statistical programming. P-MartCancer offers a series of statistical modules associated with quality assessment, peptide and protein statistics, protein quantification, and exploratory data analyses driven by the user via customized workflows and interactive visualization. Currently, P-MartCancer offers access and the capability to analyze multiple cancer proteomic datasets generated through the Clinical Proteomics Tumor Analysis Consortium at the peptide, gene, and protein levels. P-MartCancer is deployed as a web service (https://pmart.labworks.org/cptac.html), alternatively available via Docker Hub (https://hub.docker.com/r/pnnl/pmart-web/). Cancer Res; 77(21); e47-50. ©2017 AACR . ©2017 American Association for Cancer Research.

Interactive statistical packages to assist in radiotherapy management of prostate cancer. 148

International Nuclear Information System (INIS)

Altschuler, M.D.; Whittington, R.

1987-01-01

Selecting the treatment most likely to produce a satisfactory outcome is one of the major challenges in managing disease. Treatment decisions are influenced by institutional policy, personal experience, and patient characteristics. Expert systems based on a priori if-then rules are not suitable for the management of prostate cancer because of (1) a lack of general agreement among experts, (2) the large number of patient parameter possibilities that must be covered by rules, and (3) the difficulty for a clinician to state (even fuzzy) rules for each patient variable or variable combination. In this paper we describe an interactive statistical package that (1) learns an expert's decisions on cases generated by a random case simulator, (2) analyzes and explains new cases in the manner of the teaching expert, (3) can be individualized for each physician, (4) can be setup, modified, or verified quickly, and (5) can be networked with the individualized systems of other experts. An expert can use the system as a memory aid or to compare his decisions with those of his colleagues. A non-expert physician can inform his patient of the expert's likely approach. An institution can determine the domains of patient parameter space about which experts disagree and focus research resources there. Based on sampling statistics, the system weighs the relative preference for each decision path in a tree of questions specified by the expert and then integrates this information. Only statistically significant patient parametes are used for each question. The final result is a probability of each treatment option being selected by the expert. The use of the ISP will be shown for the management of prostate carcinoma. 5 refs.; 1 figure

'Combating' tropical diseases in the German colonial press.

Science.gov (United States)

Correa, Sílvio Marcus de Souza

2013-03-01

This article shows how much certain German language newspapers were a vehicule for reporting to the lay public on 'combating' tropical diseases. Through the press, immigrants and their descendents in Brazil were informed not only about the diseases which afflicted German colonists in Africa, but also about measures concerning sanitation, prophylaxis and experiments with tropical medicine, etc. Based on hemerographic sources, it shows how successful the overseas German communities were in sharing their experiences regarding health in tropical and/or sub-tropical regions.

Automation of Publications in Official Statistics using R

Directory of Open Access Journals (Sweden)

Guido Schulz

2018-03-01

Full Text Available A key task of official statistical authorities is to collect and disseminate indicators periodically. Automation using a wide range of R packages bears massive potential to cut down the resources necessary for the creation of publications. Furthermore, automation in R has the potential to improve transparency, punctuality and coherence of statistical products. The dynamic reporting engine knitr in particular allows for an efficient combination of R’s functionalities of data retrieval, data manipulation and customizable plotting on the one hand, and the layout and typesetting flexibility of LaTex or other markup languages on the other. This allows official statistical authorities to produce either ready-to-print PDFs or interactive websites while adhering to their corporate design requirements. Furthermore, dynamic reporting makes it possible to update periodic publications automatically. A work in progress example of automated statistical country profiles – a product the German Federal Statistical Office regularly publishes based on a wide range of official international sources – will be presented to illustrate both advantages and challenges in the practical use of dynamic reporting using R and knitr in particular.

Understanding Cancer Prognosis

Medline Plus

Full Text Available ... Contact Dictionary Search About Cancer Causes and Prevention Risk Factors Genetics Cancer Prevention Overview Research Cancer Screening ... Is Cancer Cancer Statistics Cancer Disparities Causes & Prevention Risk Factors Genetics Cancer Prevention Overview Screening Cancer Screening ...

Understanding Cancer Prognosis

Medline Plus

Full Text Available ... Search About Cancer Causes and Prevention Risk Factors Genetics Cancer Prevention Overview Research Cancer Screening Cancer Screening ... Cancer Statistics Cancer Disparities Causes & Prevention Risk Factors Genetics Cancer Prevention Overview Screening Cancer Screening Overview Screening ...

German energy market 2014; Deutscher Energiemarkt 2014

Energy Technology Data Exchange (ETDEWEB)

Schiffer, Hans-Wilhelm [World Energy Council, London (United Kingdom). World Energy Resources; Weltenergierat - Deutschland, Berlin (Germany). Arbeitsgruppe ' Energie fuer Deutschland'

2015-03-15

In 2014 the German government's primary goal of engaging German power suppliers to step up their production of renewable energy while speeding up energy efficiency improvement measures continued to dominate the debate. The present article provides an updated overview of the German energy market. Following on from last year's edition it gives a condensed synopsis of key indicators of the energy economy. Besides summarising general facts about the energy mix it goes into detail about the following individual energy resources: crude oil, natural gas, brown coal, hard coal, nuclear energy and renewable energies. It also explains current price trends in both the international and domestic markets.

German Schools Abroad: Hotspots of Elite Multilingualism?

Science.gov (United States)

Sander, Anne E; Admiraal, Wilfried

2016-01-01

While multilingualism itself is a widely analyzed topic, a study about multilingualism at German schools abroad is so far unique. This quantitative study investigates the differences in the size of German expressive and receptive vocabulary between monolingual and multilingual students, aged between 5 and 11 years. A cohort of 65 multilingual…

Lungworm Infections in German dairy cattle herds--seroprevalence and GIS-supported risk factor analysis.

Directory of Open Access Journals (Sweden)

Anne-Marie Schunn

Full Text Available In November 2008, a total of 19,910 bulk tank milk (BTM samples were obtained from dairy farms from all over Germany, corresponding to about 20% of all German dairy herds, and analysed for antibodies against the bovine lungworm Dictyocaulus viviparus by use of the recombinant MSP-ELISA. A total number of 3,397 (17.1%; n = 19,910 BTM samples tested seropositive. The prevalences in individual German federal states varied between 0.0% and 31.2% positive herds. A geospatial map was drawn to show the distribution of seropositive and seronegative herds per postal code area. ELISA results were further analysed for associations with land-use and climate data. Bivariate statistical analysis was used to identify potential spatial risk factors for dictyocaulosis. Statistically significant positive associations were found between lungworm seropositive herds and the proportion of water bodies and grassed area per postal code area. Variables that showed a statistically significant association with a positive BTM test were included in a logistic regression model, which was further refined by controlled stepwise selection of variables. The low Pseudo R(2 values (0.08 for the full model and 0.06 for the final model and further evaluation of the model by ROC analysis indicate that additional, unrecorded factors (e.g. management factors or random effects may substantially contribute to lungworm infections in dairy cows. Veterinarians should include lungworms in the differential diagnosis of respiratory disease in dairy cattle, particularly those at pasture. Monitoring of herds through BTM screening for antibodies can help farmers and veterinarians plan and implement appropriate control measures.

Variation in rates of breast cancer surgery: A national analysis based on French Hospital Episode Statistics.

Science.gov (United States)

Rococo, E; Mazouni, C; Or, Z; Mobillion, V; Koon Sun Pat, M; Bonastre, J

2016-01-01

Minimum volume thresholds were introduced in France in 2008 to improve the quality of cancer care. We investigated whether/how the quality of treatment decisions in breast cancer surgery had evolved before and after this policy was implemented. We used Hospital Episode Statistics for all women having undergone breast conserving surgery (BCS) or mastectomy in France in 2005 and 2012. Three surgical procedures considered as better treatment options were analyzed: BCS, immediate breast reconstruction (IBR) and sentinel lymph node biopsy (SLNB). We studied the mean rates and variation according to the hospital profile and volume. Between 2005 and 2012, the volume of breast cancer surgery increased by 11% whereas one third of the hospitals no longer performed this type of surgery. In 2012, the mean rate of BCS was 74% and similar in all hospitals whatever the volume. Conversely, IBR and SLNB rates were much higher in cancer centers (CC) and regional teaching hospitals (RTH) [IBR: 19% and 14% versus 8% on average; SLNB: 61% and 47% versus 39% on average]; the greater the hospital volume, the higher the IBR and SLNB rates (p < 0.0001). Overall, whatever the surgical procedure considered, inter-hospital variation in rates declined substantially in CC and RTH. We identified considerable variation in IBR and SLNB rates between French hospitals. Although more complex and less standardized than BCS, most clinical guidelines recommended these procedures. This apparent heterogeneity suggests unequal access to high-quality procedures for women with breast cancer. Copyright © 2015 Elsevier Ltd. All rights reserved.

Acquisition of German pluralization rules in monolingual and multilingual children

Directory of Open Access Journals (Sweden)

Eugen Zaretsky

2013-10-01

Full Text Available Existing studies on plural acquisition in German have relied on small samples and thus hardly deliver generalizable and differentiated results. Here, overgeneralizations of certain plural allomorphs and other tendencies in the acquisition of German plural markers are described on the basis of test data from 7,394 3- to 5-yearold monolingual German and bi/multilingual immigrant children tested with a modified, validated version of the Marburger Sprachscreening (MSS language test and 476 children tested with the SETK 3-5 language test. Classified correct and wrong answers to MSS and SETK 3-5 plural items were compared. The acquisition patterns of immigrants corresponded to those of younger German children. Both monolingual German and immigrant children demonstrated generally the same universal frequency and phonetically/phonologically based error patterns, irrespective of their linguistic background, but with different tendencies such as overgeneralization of -s by German children only.

A German colony in Jutland: the evidence of Christian names

DEFF Research Database (Denmark)

Eggert, Birgit

2013-01-01

Denmark lost the war in 1848-50 against the German States, and Danish nationalism had arisen throughout the country. For this reason the descendants of the German immigrants had a need culturally or politically to show their Danish identity through the names about 20 years before the language......In 1760, invited by king Frederik V, immigrants came to Denmark from the southern parts of Germany. Uninhabited moorlands in Jutland needed to be cultivated and the German immigrants were offered a number of inducements to settle in Viborg County. Many of the German immigrants settled in a single...... parish, Frederik’s Parish. Here the German language was used for services in the parish church until 1856. Thereafter German and Danish services alternated, and from 1870 the church language was solely Danish. This investigation shows that in 1801, after about 40 years in Denmark, the immigrants...

Maury Journals - German Vessels

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — German vessels observations, after the 1853 Brussels Conference that set International Maritime Standards, modeled after Maury Marine Standard Observations.

German neutron scattering conference. Programme and abstracts

Energy Technology Data Exchange (ETDEWEB)

Brueckel, Thomas (ed.)

2012-07-01

The German Neutron Scattering Conference 2012 - Deutsche Neutronenstreutagung DN 2012 offers a forum for the presentation and critical discussion of recent results obtained with neutron scattering and complementary techniques. The meeting is organized on behalf of the German Committee for Research with Neutrons - Komitee Forschung mit Neutronen KFN - by the Juelich Centre for Neutron Science JCNS of Forschungszentrum Juelich GmbH. In between the large European and international neutron scattering conferences ECNS (2011 in Prague) and ICNS (2013 in Edinburgh), it offers the vibrant German and international neutron community an opportunity to debate topical issues in a stimulating atmosphere. Originating from ''BMBF Verbundtreffen'' - meetings for projects funded by the German Federal Ministry of Education and Research - this conference series has a strong tradition of providing a forum for the discussion of collaborative research projects and future developments in the field of research with neutrons in general. Neutron scattering, by its very nature, is used as a powerful probe in many different disciplines and areas, from particle and condensed matter physics through to chemistry, biology, materials sciences, engineering sciences, right up to geology and cultural heritage; the German Neutron Scattering Conference thus provides a unique chance for exploring interdisciplinary research opportunities. It also serves as a showcase for recent method and instrument developments and to inform users of new advances at neutron facilities.

German neutron scattering conference. Programme and abstracts

International Nuclear Information System (INIS)

Brueckel, Thomas

2012-01-01

The German Neutron Scattering Conference 2012 - Deutsche Neutronenstreutagung DN 2012 offers a forum for the presentation and critical discussion of recent results obtained with neutron scattering and complementary techniques. The meeting is organized on behalf of the German Committee for Research with Neutrons - Komitee Forschung mit Neutronen KFN - by the Juelich Centre for Neutron Science JCNS of Forschungszentrum Juelich GmbH. In between the large European and international neutron scattering conferences ECNS (2011 in Prague) and ICNS (2013 in Edinburgh), it offers the vibrant German and international neutron community an opportunity to debate topical issues in a stimulating atmosphere. Originating from ''BMBF Verbundtreffen'' - meetings for projects funded by the German Federal Ministry of Education and Research - this conference series has a strong tradition of providing a forum for the discussion of collaborative research projects and future developments in the field of research with neutrons in general. Neutron scattering, by its very nature, is used as a powerful probe in many different disciplines and areas, from particle and condensed matter physics through to chemistry, biology, materials sciences, engineering sciences, right up to geology and cultural heritage; the German Neutron Scattering Conference thus provides a unique chance for exploring interdisciplinary research opportunities. It also serves as a showcase for recent method and instrument developments and to inform users of new advances at neutron facilities.

Late gastrointestinal and urogenital side-effects after radiotherapy – Incidence and prevalence. Subgroup-analysis within the prospective Austrian–German phase II multicenter trial for localized prostate cancer

International Nuclear Information System (INIS)

Schmid, Maximilian P.; Pötter, Richard; Bombosch, Valentin; Sljivic, Samir; Kirisits, Christian; Dörr, Wolfgang; Goldner, Gregor

2012-01-01

Purpose: In general late side-effects after prostate cancer radiotherapy are presented by the use of actuarial incidence rates. The aim of this analysis was to describe additional relevant aspects of late side effects after prostate cancer radiotherapy. Materials and methods: All 178 primary prostate-cancer patients were treated within the Austrian–German multicenter trial by three-dimensional radiotherapy up to a local dose of 70 Gy (low/intermediate-risk) or 74 Gy (high-risk), respectively. Late gastrointestinal/urogenital (GI/GU) side-effects were prospectively assessed by the use of EORTC/RTOG score. Maximum side-effects, actuarial incidence rate and prevalence rates, initial appearance and duration of ⩾grade 2 toxicity were evaluated. Results: Median follow-up was 74 months. Late GI/GU side-effects ⩾grade 2 were detected in 15% (27/178) and 22% (40/178). The corresponding 5-year actuarial incidence rates for GI/GU side-effects were 19% and 23%, whereas the prevalence was 1–2% and 2–7% after 5 years, respectively. Late side effects ⩾grade 2 appeared within 5 years after radiotherapy in all patients with GI side-effects (27/27) and in 85% (34/40) of the patients with GU side-effects, respectively and lasted for less than 3 years in 90% (GI) and 98% (GU). Conclusions: This study demonstrates that the majority of late GI and GU side effects after primary external beam radiotherapy for prostate cancer are transient. Using only actuarial incidence rates for reporting side effects may lead to misinterpretation or overestimation. The combination of incidence and prevalence rates provides a more comprehensive view on the complex issue of late side effects.

German words: still used by Japanese obstetrics and gynecology doctors.

Science.gov (United States)

Matsubara, Shigeki

2018-03-01

German used to be frequently employed in Japanese obstetric and gynecologic (OBGYN) practice; however, it is now less frequently used. Description and analysis of this situation may shed some light on the change of OBGYN practice and education in Japan, which may at least partly hold true to counties other than Japan. Three eras were classified according to the relationship between German and Japanese OBGYN, with each era characterized. Frequently used German words in Japanese OBGYN practice were described as examples. German words have become less frequently used with each successive generation. Even though English may suffice in practical OBGYN practice, German usage will still be passed on to these new generations.

Understanding Cancer Prognosis

Medline Plus

Full Text Available ... Menu Contact Dictionary Search About Cancer Causes and Prevention Risk Factors Genetics Cancer Prevention Overview Research Cancer Screening ... What Is Cancer Cancer Statistics Cancer Disparities Causes & Prevention Risk Factors Genetics Cancer Prevention Overview Screening Cancer Screening ...

Dictionary of control technology. Pneumatics, hydraulics, electronics. English-German, German-English. Woerterbuch der Steuerungstechnik. Pneumatik, Hydraulik, Elektronik. Deutsch-Englisch, Englisch-Deutsch

Energy Technology Data Exchange (ETDEWEB)

Budd, F

1988-01-01

The English-German/German-English dictionary covers the complete field of control technology present in industry today. The subjects represent appropriate terms from hydraulics, pneumatics, electrical engineering, electronics, data processing, administration, and training. (DG).

Christian mission agencies and the question of slavery in German ...

African Journals Online (AJOL)

... to the imperial designs of their government, with little commitment to improving the wellbeing of Cameroonians. Little wonder colonial and missionization exploitation which is inseparable from the modern understanding of slavery was at its highest during the German era. Keywords: German Cameroon, German missions, ...

When do German Firms Change their Dividends?

NARCIS (Netherlands)

Correia Da Silva, L.; Goergen, M.; Renneboog, L.D.R.

2002-01-01

Anecdotal evidence suggests that the dividend policy of German firms is more flexible than the one of their Anglo-American counterparts.This paper analyses the decision to change the dividend for a panel of 221 German firms from 1984 to 1994.The choice of the period of study is motivated by the fact

The German risk study. Pt. 2

International Nuclear Information System (INIS)

Burkart, K.

1980-01-01

A severe nuclear power plant accident can be followed by a considerable release of radioactive effluents into the atmosphere. Due to atmospheric dispersion, areas of different sizes can be contaminated. The corresponding doses can cause early illnesses, early fatalities, latent effects and genetic effects. They are accompanied by economic effects. Within the consequence model of the German Risk Study, early and late fatalities and genetically significant doses are calculated. The calculations are based on real data or phenomena such as the population around 19, present or future German sites, or 115 real weather sequences, as well as on models such as an atmospheric dispersion model, a dose model, a model of protective actions or a health effects model. Within this lecture, the consequence model applied in the German Risk Study will be discussed in detail and the results will be presented. (orig./RW)

Stop and Fricative Devoicing in European Portuguese, Italian and German.

Science.gov (United States)

Pape, Daniel; Jesus, Luis M T

2015-06-01

This paper describes a cross-linguistic production study of devoicing for European Portuguese (EP), Italian, and German. We recorded all stops and fricatives in four vowel contexts and two word positions. We computed the devoicing of the time-varying patterns throughout the stop and fricative duration. Our results show that regarding devoicing behaviour, EP is more similar to German than Italian. While Italian shows almost no devoicing of all phonologically voiced consonants, both EP and German show strong and consistent devoicing through the entire consonant. Differences in consonant position showed no effect for EP and Italian, but were significantly different for German. The height of the vowel context had an effect for German and EP. For EP, we showed that a more posterior place of articulation and low vowel context lead to significantly more devoicing. However, in contrast to German, we could not find an influence of consonant position on devoicing. The high devoicing for all phonologically voiced stops and fricatives and the vowel context influence are a surprising new result. With respect to voicing maintenance, EP is more like German than other Romance languages.

TOWARDS A GERMAN LANGUAGE FRAMEWORK FOR MALAYSIABASED MULTINATIONAL COMPANIES (MNCS

Directory of Open Access Journals (Sweden)

Siti Waltraud Brigitte Mayr

2016-08-01

Full Text Available Purpose - The aim of this study is to introduce an approach to managing business communication based on the German language needs of employees in multinational companies in Malaysia and the expectations of employers in the teaching of German in their companies. As additional variables, training for sustainable development (ESD and for maximizing the mutual understanding in personal interactions is included. Design / methodology / approach – This paper is reflecting on the spectrum of ideas about the teaching of German in German companies in Malaysia that was obtained through the author’s earlier target situation analysis in MNCs in Malaysia. In addition to a variety of methods that is incorporated to engage students in the learning process, a ‘meaning negotiation’ approach is applied in order to deal with the intercultural communication practices. Results - The paper outlines a set of topics and strategies that can assist employees in intercultural interaction contexts in a German Malaysia-based company. It draws them together into a conceptual framework of required skills in a German beginner class. Originality / Benefits - This study contributes to the current issues concerning the German mediation requirements in the management field.

Stage distribution of breast cancer diagnosed before and after implementation of population-based mammographic screening

International Nuclear Information System (INIS)

Hofvind, S.; Skaane, P.

2012-01-01

Purpose: The German mammographic screening program is very similar to the Norwegian Breast Cancer Screening Program (NBCSP), which started about 10 years earlier. This study analyzes the stage distribution of invasive breast cancers diagnosed in the pre-screening and screening period, and evaluates the overall mortality in women aged 55 - 74 in the pilot and non-pilot counties of the NBCSP. Materials and Methods: The NBCSP invites women aged 50 - 69 to participate in two-view mammography biennially. Chi-square statistics were used to compare percentages of the stage and treatment of invasive breast cancers diagnosed in women residing in the four pilot counties in the pre-screening (1984 - 1995) and screening (1996 - 2007) period. An ecological approach was used to analyze the age-specific mortality in the pilot and non-pilot counties for the period 1970 - 2007. Results: 50 % of the breast cancers diagnosed in the pre-screening period, 70 % of the cases detected with screening, 43 % of the interval cancers, and 52 % of the cancers diagnosed outside the NBCSP were stage I. Stage III + was present in 11 % of the cancers in the pre-screening period, and in 1 % of the cancers detected with screening. In the screening period, the breast cancer mortality rate decreased substantially more in the pilot counties than in the non-pilot counties. Conclusion: The stage distribution of breast cancer diagnosed in the NBCSP is prognostically favorable compared to cancers diagnosed outside the screening program. The reduction in the breast cancer mortality rate was more pronounced in the four pilot counties compared to the non-pilot counties. It is necessary to evaluate the program based on individual data. (orig.)

Results of the scientific and humanitarian projects supported by the German electricity companies (VDEW e.V.) after the Chernobyl accident

International Nuclear Information System (INIS)

Pfob, H.; Heinemann, G.

2000-01-01

The German Electricity Companies, organized by VDEW e.V., tried to support in manifold ways the areas and people affected by the Chernobyl accident in their management of the situation. Apart from their prompting numerous help projects of the German public; we must mention three efforts especially: 1. the program for partnership in security matters initiated by the German nuclear power plants has been serving a quick and efficient support of the Eastern European plants since 1990- parallel to the efforts on a European level (strategic exchange of views of the experts concerned, consultation and training on the management level, optimization of training programs). 2: the project [Scientists Help Chernobyl Children] of the Joint Committee for Radiation Research (GAST), an union of the scientific societies working on radiation research in Germany under the chairmanship of Prof. Reiners (Essen/Wuerzburg) in cooperation with Prof. Streffer (Essen), Dr. Parezke (Munich), Dr. Heinemann (Hannover) and Dr. Pfob (Karlsruhe), aims to give humanitarian and scientific help for children ill with thyroid cancer in Belarus. Therapy and training, molecular biological examinations, dosimetry, and risk evaluation, as well as consultation and coordination in Minsk are parts of the project. 3: the project of the Radiation Cytogenetics Association (RCA) under the chairmanship of Prof. Bauchinger (GSF Muenchen) has been giving coordinated help with biological dosimetry to institutions and scientist in the states of the former USSR. Through retrospective biological dosimetry, especially the employment of the FISH (fluorescence in situ hybridization)-technology for the assessment of so-called stable translocations, both individual and population doses were analyzed. All three of these projects, even if to a different extent, have been leading to new and unique results up to the present day. Especially the GAST-project has been marked to a high extent by its humanitarian help for the

Analytical and statistical consideration on the use of the ISAG-ICAR-SNP bovine panel for parentage control, using the Illumina BeadChip technology: example on the German Holstein population.

Science.gov (United States)

Schütz, Ekkehard; Brenig, Bertram

2015-02-05

Parentage control is moving from short tandem repeats- to single nucleotide polymorphism (SNP) systems. For SNP-based parentage control in cattle, the ISAG-ICAR Committee proposes a set of 100/200 SNPs but quality criteria are lacking. Regarding German Holstein-Friesian cattle with only a limited number of evaluated individuals, the exclusion probability is not well-defined. We propose a statistical procedure for excluding single SNPs from parentage control, based on case-by-case evaluation of the GenCall score, to minimize parentage exclusion, based on miscalled genotypes. Exclusion power of the ISAG-ICAR SNPs used for the German Holstein-Friesian population was adjusted based on the results of more than 25,000 individuals. Experimental data were derived from routine genomic selection analyses of the German Holstein-Friesian population using the Illumina BovineSNP50 v2 BeadChip (20,000 individuals) or the EuroG10K variant (7000 individuals). Averages and standard deviations of GenCall scores for the 200 SNPs of the ISAG-ICAR recommended panel were calculated and used to calculate the downward Z-value. Based on minor allelic frequencies in the Holstein-Friesian population, one minus exclusion probability was equal to 1.4×10⁻¹⁰ and 7.2×10⁻²⁶, with one and two parents, respectively. Two monomorphic SNPs from the 100-SNP ISAG-ICAR core-panel did not contribute. Simulation of 10,000 parentage control combinations, using the GenCall score data from both BeadChips, showed that with a Z-value greater than 3.66 only about 2.5% parentages were excluded, based on the ISAG-ICAR recommendations (core-panel: ≥ 90 SNPs for one, ≥ 85 SNPs for two parents). When applied to real data from 1750 single parentage assessments, the optimal threshold was determined to be Z = 5.0, with only 34 censored cases and reduction to four (0.2%) doubtful parentages. About 70 parentage exclusions due to weak genotype calls were avoided, whereas true exclusions (n = 34) were

[Skin cancer as occupational disease].

Science.gov (United States)

Bauer, A

2016-11-01

The incidence of epithelial skin neoplasms, such as squamous cell carcinoma and basal cell carcinoma is significantly increasing worldwide. Leisure time solar UV exposure is causative in the overwhelming majority of cases in the general population; however, occupational exposure is responsible for a certain percentage of cases. Employees with a relevant exposure to polycyclic aromatic hydrocarbons in soot, raw paraffin, coal tar, anthracene, pitch or similar substances, to sunlight in outdoor occupations as well as to arsenic and ionizing radiation have a significantly increased risk to develop occupational skin cancer compared to the general population. In the official occupational disease list in the appendix of the German by-law on occupational diseases, the following occupational diseases concerning skin cancer are listed: BK 5102 "skin cancer and carcinoma in situ caused by soot, raw paraffin, coal tar, anthracene, pitch or similar substances" (e.g. various solid paraffins, asphalt and mazut as well as mineral oils, grease, cylinder and drilling oils), BK 5103 "squamous cell carcinoma or multiple actinic keratosis caused by natural UV radiation", BK 1108 "diseases caused by arsenic and its compounds" and BK 2402 "diseases caused by ionizing radiation". For further occupational exposure to carcinogenic substances and potential occupationally acquired skin tumors, no official lists are currently available. These cancers might be considered under a special opt out paragraph in the German Social Law (§ 9 para 2 SGB VII). Tumors in scars after occupational skin trauma or occupational burns are compensated as consequences of work accidents. The current official list of occupational skin cancers and new developments for expert opinions are described in this article.

Reconstruction of an Input-Output Table for Germany in 1936 : Conceptual and Empirical-Statistical Problems

NARCIS (Netherlands)

Fremdling, Rainer; Staeglin, Reiner

2012-01-01

The objective of this contribution is to present the final results of a long-term research project which aimed at constructing an input-output table for Germany in 1936. Our research can be seen as follow-up of the activities of the German Imperial Statistical Office (Statistisches Reichsamt) which

Mutation analysis of the ERCC4/FANCQ gene in hereditary breast cancer.

Directory of Open Access Journals (Sweden)

Sandra Kohlhase

Full Text Available The ERCC4 protein forms a structure-specific endonuclease involved in the DNA damage response. Different cancer syndromes such as a subtype of Xeroderma pigmentosum, XPF, and recently a subtype of Fanconi Anemia, FA-Q, have been attributed to biallelic ERCC4 gene mutations. To investigate whether monoallelic ERCC4 gene defects play some role in the inherited component of breast cancer susceptibility, we sequenced the whole ERCC4 coding region and flanking untranslated portions in a series of 101 Byelorussian and German breast cancer patients selected for familial disease (set 1, n = 63 or for the presence of the rs1800067 risk haplotype (set 2, n = 38. This study confirmed six known and one novel exonic variants, including four missense substitutions but no truncating mutation. Missense substitution p.R415Q (rs1800067, a previously postulated breast cancer susceptibility allele, was subsequently screened for in a total of 3,698 breast cancer cases and 2,868 controls from Germany, Belarus or Russia. The Gln415 allele appeared protective against breast cancer in the German series, with the strongest effect for ductal histology (OR 0.67; 95%CI 0.49; 0.92; p = 0.003, but this association was not confirmed in the other two series, with the combined analysis yielding an overall Mantel-Haenszel OR of 0.94 (95% CI 0.81; 1.08. There was no significant effect of p.R415Q on breast cancer survival in the German patient series. The other three detected ERCC4 missense mutations included two known rare variants as well as a novel substitution, p.E17V, that we identified on a p.R415Q haplotype background. The p.E17V mutation is predicted to be probably damaging but was present in just one heterozygous patient. We conclude that the contribution of ERCC4/FANCQ coding mutations to hereditary breast cancer in Central and Eastern Europe is likely to be small.

USING EDUCATIONAL MARBLE GAMES IN GERMAN LANGUAGE TEACHING

Directory of Open Access Journals (Sweden)

HASAN COŞKUN

2015-09-01

Full Text Available The aim of this article is to show how German students can be motivated by learning games. Apart from the development and didacticisation of the learning game “Marbles”, the attitude of Turkish families and language teaching educational establishments and the support of the DaF lessons by German mediating institutions in Turkey will be considered. The attitude of Turkish families to learning foreign languages is mostly positive. Turkish educational authorities and those responsible for education take various measures to expand foreign language teaching availability in the schools. German institutions which provide teachers (Goethe-Institut, ZfA, DAAD promote the improvement of German teaching in Turkey. Nevertheless, the quality of German teaching is not satisfactory mostly because the available teachers are not adequately qualified, teacher training is remote from practice, the quality of text books and teaching materials, the traditions of learning, the excessively large classes, inadequate learning environment (language cabinets and equipment, the nature and method of central examinations (multiple choice and their significance in the Turkish educational system. In the long-term, this leads to frustration in both teachers and students. The Turkish educational authorities initially took measures to expand the availability of language teaching in the course of harmonisation of the Turkish educational system to that of the EU e.g. the introduction of a second foreign language. German mediating institutions ensure reasonable further training for teachers locally and in Germany and support the creation of teaching materials etc.

75 FR 62453 - German-American Day, 2010

Science.gov (United States)

2010-10-12

... a better life. The German men and women who braved numerous perils to cross the Atlantic long ago... influenced our country in all walks of life, and their resolve lives on in the men, women, and families of... not only the countless achievements and rich heritage of German Americans, but also the strong ties...

Cancer in children residing near nuclear power plants: an open question.

Science.gov (United States)

Ghirga, Giovanni

2010-09-10

Global warming and the established responsibility of the anthropogenic emissions of greenhouse gases represent a strong push towards the construction of new nuclear power plants (NPPs) to cope with the growing energy needs. The toxicity of nuclear waste associated with the extreme difficulty of their disposal and increase in cancer mortality and incidence following occupational radiation exposure are considered the only health problems. A search of scientific articles and government documents published since January 1, 1980 to July 1, 2010 was performed to evaluate cancer rate and mortality in residents, particularly children, in the vicinity of NPPs. A recent well conducted state-of-the-art case-control study of childhood cancers in the areas around German NPPs (KiKK study) showed a statistically significant cancers (2.2-fold increase in leukemia and a 1.6-fold increase in solid tumor) among children under five years of age living in the inner 5 km circle around NPPs when compared to residence outside this area. These findings have been confirmed by two meta-analyses. Nevertheless, other UK, France, Spain and Finland studies did not find cancer incidence and/or death increase near NPPs. Increased cancer risk near NPPs remains in fact an open question. The stronger evidence from the KiKK study suggests there may well be such increases at least in children regardless of the country in which nuclear reactors are located. In fact, few months ago the U.S. Nuclear Regulatory Commission has asked the National Academy of Sciences (NAS) to perform a state-of-the-art study on cancer risk for populations surrounding NPPs.

Cancer in children residing near nuclear power plants: an open question

Directory of Open Access Journals (Sweden)

Ghirga Giovanni

2010-09-01

Full Text Available Abstract Background Global warming and the established responsibility of the anthropogenic emissions of greenhouse gases represent a strong push towards the construction of new nuclear power plants (NPPs to cope with the growing energy needs. The toxicity of nuclear waste associated with the extreme difficulty of their disposal and increase in cancer mortality and incidence following occupational radiation exposure are considered the only health problems. Methods A search of scientific articles and government documents published since January 1, 1980 to July 1, 2010 was performed to evaluate cancer rate and mortality in residents, particularly children, in the vicinity of NPPs. Results A recent well conducted state-of-the-art case-control study of childhood cancers in the areas around German NPPs (KiKK study showed a statistically significant cancers (2.2-fold increase in leukemia and a 1.6-fold increase in solid tumor among children under five years of age living in the inner 5 km circle around NPPs when compared to residence outside this area. These findings have been confirmed by two meta-analyses. Nevertheless, other UK, France, Spain and Finland studies did not find cancer incidence and/or death increase near NPPs. Conclusions Increased cancer risk near NPPs remains in fact an open question. The stronger evidence from the KiKK study suggests there may well be such increases at least in children regardless of the country in which nuclear reactors are located. In fact, few months ago the U.S. Nuclear Regulatory Commission has asked the National Academy of Sciences (NAS to perform a state-of-the-art study on cancer risk for populations surrounding NPPs.

[History of German-Baltic relations in medicine].

Science.gov (United States)

Tankler, H; Laschinski, G; Roots, I

2004-04-30

Today, the three Baltic countries Estonia, Latvia and Lithuania, have well-known medical faculties with international standing. Their individual histories are briefly outlined. However, relations of the German academic world were closest with the university of Dorpat (today: Tartu). It was re-opened in 1802 by tsar Alexander I in order to keep young Baltic people from studying abroad. The medical faculty was its biggest faculty. The university was Russian, but the official language was German. So many a German professor came to Dorpat and many professors from Dorpat were offered a chair at a German university. The scientific imports connected Dorpat with other centres of West-European science, they brought knowledge and ideas and an exchange of information. The standard was high, and among the teaching staff was a handsome number of medical celebrities, e.g. the anatomist August Rauber and the surgeon Ernst von Bergmann. In Dorpat, Rudolf Buchheim brought a new science, experimental pharmacology, into being, which his pupil and successor, Oswald Schmiedeberg, fully established and propagated all over the world.

Long-Term Health-Related Quality of Life in German Patients with Juvenile Idiopathic Arthritis in Comparison to German General Population.

Directory of Open Access Journals (Sweden)

Swaantje Barth

Full Text Available Aims of the study were to investigate health-related quality of life (HRQOL in adult patients with former diagnosis of Juvenile Idiopathic Arthritis (JIA, to compare their HRQOL with the general population and to identify factors related to a poor outcome.In 2012, a cross-sectional survey was performed by mailing a questionnaire to a large cohort of former and current patients of the German Centre for Rheumatology in Children and Adolescents. Only adult patients (≥18 years with a diagnosis compatible with JIA were included (n = 2592; response 66%. The questionnaire included information about HRQOL (EQ5D, disease-related questions and socio-demographics. Prevalence and 95% confidence intervals (CI of problems with mobility, self-care, usual activities, pain and anxiety/depression were standardized to the German general population. Factors associated with low HRQOL in JIA patients were identified using logistic regression models.Sixty-two percent of the study population was female; age range was 18-73 years. In all dimensions, JIA patients reported statistically significantly more problems than the general population with largest differences in the pain dimension (JIA patients 56%; 95%CI 55-58%; general population 28%; 26-29% and the anxiety/depression dimension (28%; 27-29% vs. 4%; 4-5%. Lower HRQOL in JIA patients was associated with female sex, older age, lower level of education, still being under rheumatic treatment and disability.HRQOL in adult JIA patients is considerably lower than in the general population. As this cohort includes historic patients the new therapeutic schemes available today are expected to improve HRQOL in future.

Long-Term Health-Related Quality of Life in German Patients with Juvenile Idiopathic Arthritis in Comparison to German General Population.

Science.gov (United States)

Barth, Swaantje; Haas, Johannes-Peter; Schlichtiger, Jenny; Molz, Johannes; Bisdorff, Betty; Michels, Hartmut; Hügle, Boris; Radon, Katja

2016-01-01

Aims of the study were to investigate health-related quality of life (HRQOL) in adult patients with former diagnosis of Juvenile Idiopathic Arthritis (JIA), to compare their HRQOL with the general population and to identify factors related to a poor outcome. In 2012, a cross-sectional survey was performed by mailing a questionnaire to a large cohort of former and current patients of the German Centre for Rheumatology in Children and Adolescents. Only adult patients (≥18 years) with a diagnosis compatible with JIA were included (n = 2592; response 66%). The questionnaire included information about HRQOL (EQ5D), disease-related questions and socio-demographics. Prevalence and 95% confidence intervals (CI) of problems with mobility, self-care, usual activities, pain and anxiety/depression were standardized to the German general population. Factors associated with low HRQOL in JIA patients were identified using logistic regression models. Sixty-two percent of the study population was female; age range was 18-73 years. In all dimensions, JIA patients reported statistically significantly more problems than the general population with largest differences in the pain dimension (JIA patients 56%; 95%CI 55-58%; general population 28%; 26-29%) and the anxiety/depression dimension (28%; 27-29% vs. 4%; 4-5%). Lower HRQOL in JIA patients was associated with female sex, older age, lower level of education, still being under rheumatic treatment and disability. HRQOL in adult JIA patients is considerably lower than in the general population. As this cohort includes historic patients the new therapeutic schemes available today are expected to improve HRQOL in future.

German-American Studies in a New Vein: Resources and Possibilities

Science.gov (United States)

Herminghouse, Patricia

1976-01-01

The history of German-American culture is outlined and several indexes and resources for material on German culture in America are listed. Approaches to such studies include regional focus, German theater in America, and oral history to bring classroom activities closer to real world patterns and problems. (CHK)

Facebook Used in a German Film Project

Science.gov (United States)

Leier, Vera

2011-01-01

Looking for a way to make German language study more relevant and to step out of the conventional classroom setting, I introduced Facebook (FB) as a learning platform to my intermediate German students at the University of Canterbury, New Zealand. The students took part in a film competition. A FB group was created and the films were uploaded. The…

Stuttering Characteristics of German-English Bilingual Speakers

Science.gov (United States)

Schafer, Martina; Robb, Michael P.

2012-01-01

The purpose of this study was to examine stuttering behavior in German-English bilingual people who stutter (PWS), with particular reference to the frequency of stuttering on content and function words. Fifteen bilingual PWS were sampled who spoke German as the first language (L1) and English as a second language (L2). Conversational speech was…

Teaching Controversal Topics in Contemporary German Culture through Hip-Hop

Science.gov (United States)

Putnam, Michael

2006-01-01

This article discusses the rich cultural resources embedded with German hip-hop music and its potential impact on the foreign language classroom. In particular, this article suggests methods and materials for integrating German hip-hop music in the discussion of recent controversial cultural events and attitudes in German after the "Wende."

Why all John’s friends are Dutch, not German; on differences in West Germanic in the interaction between universal quantifiers and genitives

Directory of Open Access Journals (Sweden)

Robert Cirillo

2014-11-01

Full Text Available Unlike English and Dutch, German does not allow a genitive to follow a universal quantifier: (i All John’s friends… (ii Al Jans vrienden… (Dutch (iii *All(e Johanns Freunde… (German In this article I show that this discrepancy results from two facts. Firstly, the German Saxon Genitive is a true case ending assigned in [Spec, NP] or [Spec, PossP] while in Dutch and English genitive case cannot be assigned at the N or n level (without a preposition and the Saxon Genitive is more like a possessive adjective, initiating as the head of PossP and terminating in D. Secondly, in Germanic, D or [Spec, DP] must be overtly occupied in case of definiteness, and if the D node is already overtly occupied, and if genitive case has already been assigned, there is no motivation for moving a genitive phrase to the D level. I also show that Germanic dative of possession constructions (possessor doubling can be explained within the same framework. Finally, there is a brief discussion of the potential applicability of this analysis to Scandinavian.

German precursor study: methods and results

International Nuclear Information System (INIS)

Hoertner, H.; Frey, W.; von Linden, J.; Reichart, G.

1985-01-01

This study has been prepared by the GRS by contract of the Federal Minister of Interior. The purpose of the study is to show how the application of system-analytic tools and especially of probabilistic methods on the Licensee Event Reports (LERs) and on other operating experience can support a deeper understanding of the safety-related importance of the events reported in reactor operation, the identification of possible weak points, and further conclusions to be drawn from the events. Additionally, the study aimed at a comparison of its results for the severe core damage frequency with those of the German Risk Study as far as this is possible and useful. The German Precursor Study is a plant-specific study. The reference plant is Biblis NPP with its very similar Units A and B, whereby the latter was also the reference plant for the German Risk Study

Adherence to the breast cancer surveillance program for women at risk for familial breast and ovarian cancer versus overscreening: a monocenter study in Germany.

Science.gov (United States)

Vetter, Lisa; Keller, Monika; Bruckner, Thomas; Golatta, Michael; Eismann, Sabine; Evers, Christina; Dikow, Nicola; Sohn, Christof; Heil, Jörg; Schott, Sarah

2016-04-01

Breast cancer (BC) is the leading cancer among women worldwide and in 5-10 % of cases is of hereditary origin, mainly due to BRCA1/2 mutations. Therefore, the German Consortium for Familial Breast and Ovarian Cancer (HBOC) with its 15 specialized academic centers offers families at high risk for familial/hereditary cancer a multimodal breast cancer surveillance program (MBCS) with regular breast MRI, mammography, ultrasound, and palpation. So far, we know a lot about the psychological effects of genetic testing, but we know little about risk-correlated adherence to MBCS or prophylactic surgery over time. The aim of this study was to investigate counselees' adherence to recommendations for MBCS in order to adjust the care supply and define predictors for incompliance. All counselees, who attended HBOC consultation at the University Hospital Heidelberg between July 01, 2009 and July 01, 2011 were eligible to participate. A tripartite questionnaire containing sociodemographic information, psychological parameters, behavioral questions, and medical data collection from the German consortium were used. A high participation rate was achieved among the study population, with 72 % returning the questionnaire. This study showed a rate of 59 % of full-adherers to the MBCS. Significant predictors for partial or full adherence were having children (p = 0.0221), younger daughters (p = 0.01795), a higher awareness of the topic HBOC (p = 0.01795, p breast cancer risk (p breast cancer surveillance program for women at risk for familial breast and ovarian cancer versus overscreening-a monocenter study in Germany.

Polyamine Metabolites Profiling for Characterization of Lung and Liver Cancer Using an LC-Tandem MS Method with Multiple Statistical Data Mining Strategies: Discovering Potential Cancer Biomarkers in Human Plasma and Urine

Directory of Open Access Journals (Sweden)

Huarong Xu

2016-08-01

Full Text Available Polyamines, one of the most important kind of biomarkers in cancer research, were investigated in order to characterize different cancer types. An integrative approach which combined ultra-high performance liquid chromatography—tandem mass spectrometry detection and multiple statistical data processing strategies including outlier elimination, binary logistic regression analysis and cluster analysis had been developed to discover the characteristic biomarkers of lung and liver cancer. The concentrations of 14 polyamine metabolites in biosamples from lung (n = 50 and liver cancer patients (n = 50 were detected by a validated UHPLC-MS/MS method. Then the concentrations were converted into independent variables to characterize patients of lung and liver cancer by binary logic regression analysis. Significant independent variables were regarded as the potential biomarkers. Cluster analysis was engaged for further verifying. As a result, two values was discovered to identify lung and liver cancer, which were the product of the plasma concentration of putrescine and spermidine; and the ratio of the urine concentration of S-adenosyl-l-methionine and N-acetylspermidine. Results indicated that the established advanced method could be successfully applied to characterize lung and liver cancer, and may also enable a new way of discovering cancer biomarkers and characterizing other types of cancer.

LaissezFair: A Case for Greening the Business German Curriculum

Science.gov (United States)

Gonglewski, Margaret; Helm, Anna

2013-01-01

An effective way to teach about sustainability and environmentally conscious practices in German language, literature, and culture programs is within the context of a business German course. In this article we first situate educational sustainability in the US, leading into an examination of why the context of German business can be particularly…

Error Patterns in Young German Children's "Wh"-Questions

Science.gov (United States)

Schmerse, Daniel; Lieven, Elena; Tomasello, Michael

2013-01-01

In this article we report two studies: a detailed longitudinal analysis of errors in "wh"-questions from six German-learning children (age 2 ; 0-3 ; 0) and an analysis of the prosodic characteristics of "wh"-questions in German child-directed speech. The results of the first study demonstrate that German-learning children…

Curriculum design and German student exchange for Sino-German Bachelor program majored in optoelectronics engineering

Science.gov (United States)

Zheng, Jihong; Fuhrmann, Thomas; Xu, Boqing; Schreiner, Rupert; Jia, Hongzhi; Zhang, Wei; Wang, Ning; Seebauer, Gudrun; Zhu, Jiyan

2017-08-01

Different higher education backgrounds in China and Germany led to challenges in the curriculum design at the beginning of our cooperative bachelor program in Optoelectronics Engineering. We see challenges in different subject requirements from both sides and in the German language requirements for Chinese students. The curriculum was optimized according to the ASIIN criteria, which makes it acceptable and understandable by both countries. German students are integrated into the Chinese class and get the same lectures like their Chinese colleagues. Intercultural and curriculum challenges are successfully solved. The results are summarized to provide an example for other similar international programs.

Vaginal Cancer Overview

Science.gov (United States)

... are here Home > Types of Cancer > Vaginal Cancer Vaginal Cancer This is Cancer.Net’s Guide to Vaginal Cancer. Use the menu below to choose the ... social workers, and patient advocates. Cancer.Net Guide Vaginal Cancer Introduction Statistics Medical Illustrations Risk Factors and ...

Comparison of susceptibility for hip dysplasia between Rottweilers and German Shepherd Dogs

International Nuclear Information System (INIS)

Popovitch, C.A.; Smith, G.K.; Gregor, T.P.; Sholer, F.S.

1995-01-01

Passive laxity of the coxofemoral joints, as measured quantitatively by radiographing the joints under stress, has been shown to be an accurate measure of the risk for developing degenerative joint disease (DJD) of the coxofemoral joints. Seventy-four Rottweilers between 12 and 40 months old were evaluated subjectively for radiographic evidence of DJD, using the ventrodorsal view of the pelvis with the coxofemoral joints fully extended and the knees internally rotated (standard hip-extended view). Effect of age, sex, weight, and distraction index on the risk of developing DJD was evaluated by use of a logistic regression model. Results were compared with those from a group of German Shepherd Dogs. Results indicated that in Rottweilers the distraction index was the only statistically significant predictor of the risk of developing DJD of the coxofemoral joint. When German Shepherd Dogs were included in the model, they had a significantly greater risk of developing DJD than did Rottweilers. This finding provides further support for the theory that there are differences in disease susceptibility among breeds and emphasizes the need to develop disease susceptibility curves for all breeds affected by hip dysplasia to facilitate accurate, scientifically based recommendations for breeding or treatment

Cancer in Children and Adolescents | Office of Cancer Genomics

Science.gov (United States)

View a fact sheet that has statistics as well as information about types, causes, and treatments of cancers in children and adolescents in the United States. https://www.cancer.gov/types/childhood-cancers/child-adolescent-cancers-fact-sheet

[Central online quality assurance in radiology: an IT solution exemplified by the German Breast Cancer Screening Program].

Science.gov (United States)

Czwoydzinski, J; Girnus, R; Sommer, A; Heindel, W; Lenzen, H

2011-09-01

Physical-technical quality assurance is one of the essential tasks of the National Reference Centers in the German Breast Cancer Screening Program. For this purpose the mammography units are required to transfer the measured values of the constancy tests on a daily basis and all phantom images created for this purpose on a weekly basis to the reference centers. This is a serious logistical challenge. To meet these requirements, we developed an innovative software tool. By the end of 2005, we had already developed web-based software (MammoControl) allowing the transmission of constancy test results via entry forms. For automatic analysis and transmission of the phantom images, we then introduced an extension (MammoControl DIANA). This was based on Java, Java Web Start, the NetBeans Rich Client Platform, the Pixelmed Java DICOM Toolkit and the ImageJ library. MammoControl DIANA was designed to run locally in the mammography units. This allows automated on-site image analysis. Both results and compressed images can then be transmitted to the reference center. We developed analysis modules for the daily and monthly consistency tests and additionally for a homogeneity test. The software we developed facilitates the immediate availability of measurement results, phantom images, and DICOM header data in all reference centers. This allows both targeted guidance and short response time in the case of errors. We achieved a consistent IT-based evaluation with standardized tools for the entire screening program in Germany. © Georg Thieme Verlag KG Stuttgart · New York.

Central online quality assurance in radiology. An IT solution exemplified by the German Breast Cancer Screening Program

International Nuclear Information System (INIS)

Czwoydzinski, J.; Girnus, R.; Sommer, A.; Heindel, W.; Lenzen, H.; Universitaetsklinikum Muenster

2011-01-01

Purpose: Physical-technical quality assurance is one of the essential tasks of the National Reference Centers in the German Breast Cancer Screening Program. For this purpose the mammography units are required to transfer the measured values of the constancy tests on a daily basis and all phantom images created for this purpose on a weekly basis to the reference centers. This is a serious logistical challenge. To meet these requirements, we developed an innovative software tool. Materials and Methods: By the end of 2005, we had already developed web-based software (MammoControl) allowing the transmission of constancy test results via entry forms. For automatic analysis and transmission of the phantom images, we then introduced an extension (MammoControl DIANA). This was based on Java, Java Web Start, the NetBeans Rich Client Platform, the Pixelmed Java DICOM Toolkit and the ImageJ library. Results: MammoControl DIANA was designed to run locally in the mammography units. This allows automated on-site image analysis. Both results and compressed images can then be transmitted to the reference center. We developed analysis modules for the daily and monthly consistency tests and additionally for a homogeneity test. Conclusion: The software we developed facilitates the immediate availability of measurement results, phantom images, and DICOM header data in all reference centers. This allows both targeted guidance and short response time in the case of errors. We achieved a consistent IT-based evaluation with standardized tools for the entire screening program in Germany. (orig.)

Beginning German in Grade Three: MLA Teacher's Guide. A Course of Study Including Methods, Materials, and Aids for Teaching Conversational German to Third-Grade Children.

Science.gov (United States)

Wittman, Nora E.; And Others

This guide is planned to help the FLES teacher develop pleasurable language learning experiences in spoken German for children at the third-grade level. Experiences included in this guide present German in life situations, as well as insight into German culture. The guide offers suggestions for classroom procedures, and detailed directions are…

Attitudes of members of the German Society for Palliative Medicine toward complementary and alternative medicine for cancer patients.

Science.gov (United States)

Conrad, A C; Muenstedt, K; Micke, O; Prott, F J; Muecke, R; Huebner, J

2014-07-01

A high proportion of cancer patients use complementary and alternative medicine (CAM). In oncology, risks of CAM are side effects and interactions. Our aim was to conduct a survey on professionals in palliative care regarding attitudes toward CAM. An internet-based survey with a standardized questionnaire was sent to all members of the German Society for Palliative Care. The questionnaire collected data on attitude toward CAM and experiences. Six hundred and ninety questionnaires (19 %) were returned (49 % physicians, 35 % nurses, 3 % psychologists). Acceptance of CAM is high (92 % for complementary and 54 % for alternative medicine). Most participants had already been asked on CAM by patients (95 %) and relatives (89 %). Forty-four percent already had used complementary methods and 5 % alternative methods. Only 21 % think themselves adequately informed. Seventy-four percent would use complementary methods in a patient with advanced tumor, and 62 % would use alternative therapy in patients if there was no other therapy. Even from those who are skeptical 45 % would treat a patient with alternative methods. In order to inform patients on CAM and to further patients' autonomy, evidence on benefits and harms of CAM must be provided. As awareness of risks from CAM is low and critical appraisal especially of alternative medicine missing, but interest on information on CAM is high, experts should provide evidence-based recommendations for CAM in palliative care to members of different professions. This could be done by a curriculum focusing on the most often used CAM methods.

Breast Cancer Overview

Science.gov (United States)

... are here Home > Types of Cancer > Breast Cancer Breast Cancer This is Cancer.Net’s Guide to Breast Cancer. Use the menu below to choose the Overview/ ... social workers, and patient advocates. Cancer.Net Guide Breast Cancer Introduction Statistics Medical Illustrations Risk Factors and Prevention ...

Statistical analysis of the early phase of SBO accident for PWR

Energy Technology Data Exchange (ETDEWEB)

Kozmenkov, Yaroslav, E-mail: y.kozmenkov@hzdr.de; Jobst, Matthias, E-mail: m.jobst@hzdr.de; Kliem, Soeren, E-mail: s.kliem@hzdr.de; Schaefer, Frank, E-mail: f.schaefer@hzdr.de; Wilhelm, Polina, E-mail: p.wilhelm@hzdr.de

2017-04-01

Highlights: • Best estimate model of generic German PWR is used in ATHLET-CD simulations. • Uncertainty and sensitivity analysis of the early phase of SBO accident is presented. • Prediction intervals for occurrence of main events are evaluated. - Abstract: A statistical approach is used to analyse the early phase of station blackout accident for generic German PWR with the best estimate system code ATHLET-CD as a computation tool. The analysis is mainly focused on the timescale uncertainties of the accident events which can be detected at the plant. The developed input deck allows variations of all input uncertainty parameters relevant to the case. The list of identified and quantified input uncertainties includes 30 parameters related to the simulated physical phenomena/processes. Time uncertainties of main events as well as the major contributors to these uncertainties are defined. The uncertainty in decay heat has the highest contribution to the uncertainties of the analysed events. A linear regression analysis is used for predicting times of future events from detected times of occurred/past events. An accuracy of event predictions is estimated and verified. The presented statistical approach could be helpful for assessing and improving existing or elaborating additional emergency operating procedures aimed to prevent severe damage of reactor core.

Lungworm Infections in German Dairy Cattle Herds — Seroprevalence and GIS-Supported Risk Factor Analysis

Science.gov (United States)

Schunn, Anne-Marie; Conraths, Franz J.; Staubach, Christoph; Fröhlich, Andreas; Forbes, Andrew; Strube, Christina

2013-01-01

In November 2008, a total of 19,910 bulk tank milk (BTM) samples were obtained from dairy farms from all over Germany, corresponding to about 20% of all German dairy herds, and analysed for antibodies against the bovine lungworm Dictyocaulus viviparus by use of the recombinant MSP-ELISA. A total number of 3,397 (17.1%; n = 19,910) BTM samples tested seropositive. The prevalences in individual German federal states varied between 0.0% and 31.2% positive herds. A geospatial map was drawn to show the distribution of seropositive and seronegative herds per postal code area. ELISA results were further analysed for associations with land-use and climate data. Bivariate statistical analysis was used to identify potential spatial risk factors for dictyocaulosis. Statistically significant positive associations were found between lungworm seropositive herds and the proportion of water bodies and grassed area per postal code area. Variables that showed a statistically significant association with a positive BTM test were included in a logistic regression model, which was further refined by controlled stepwise selection of variables. The low Pseudo R2 values (0.08 for the full model and 0.06 for the final model) and further evaluation of the model by ROC analysis indicate that additional, unrecorded factors (e.g. management factors) or random effects may substantially contribute to lungworm infections in dairy cows. Veterinarians should include lungworms in the differential diagnosis of respiratory disease in dairy cattle, particularly those at pasture. Monitoring of herds through BTM screening for antibodies can help farmers and veterinarians plan and implement appropriate control measures. PMID:24040243

A German Perspective on Security Research

Science.gov (United States)

Thoma, Klaus; Hiller, Daniel; Leismann, Tobias; Drees, Birgit

Prior to 2007, there was no coherent federal approach to conceptualise and fund security research in Germany. This changed with the initiation of the national program for civil security research, managed by the German Ministry for Education and Research (BMBF). Over the course of only four years a continuous build-up of national capacities on civil security was established to better protect German citizens, commodities and infrastructures against terrorism, organised crime and the effects of man-made and natural disasters.

China as A Growing Strategic Market for German Business

Institute of Scientific and Technical Information of China (English)

Zhu Zijun

2011-01-01

@@ German Companies view China as a more strategically important market, despite their concerns over China's regulatory environment, according to a re-port from the German Chamber of Commerce in China.

Dictionary of heat exchanger technology. English-German, German-English. Woerterbuch der Waermeaustauschertechnik. Englisch-Deutsch, Deutsch-Englisch

Energy Technology Data Exchange (ETDEWEB)

Schmitz, H P [comp.

1989-01-01

This dictionary contains more than 6,000 terms and numerous explanations and comprises all types of shell-and-tube and tubular heat exchangers including condensers, feedwater heaters, air heaters, evaporators, vaporizers, steam generators, steam boilers as well as plate-and-frame heat exchangers, cooling towers, and special designs, and the related technical fields such as thermal and mass transfer, thermodynamics, fluids engineering, and strength calculation. Part 1 contains the English-German version, Part 2 the German-English version and Annex 1 the figures for explaining the most important heat exchanger designs. (orig.).

Testing Language, Testing Ethnicity? Policies and Practices Surrounding the Ethnic German "Aussiedler"

Science.gov (United States)

Schupbach, Doris

2009-01-01

"Aussiedler" are ethnic Germans from the former Soviet Union and other Eastern European countries who are granted the right to resettle in the Federal Republic of Germany (FRG) if they can provide evidence of German ancestry, attachment to the German language and culture, and ongoing assertion of German ethnicity. This article outlines…

On the contrast between Germanic and Romance negated quantifiers

OpenAIRE

Robert Cirillo

2009-01-01

Universal quantifiers can be stranded in the manner described by Sportiche (1988), Giusti (1990) and Shlonsky (1991) in both the Romance and Germanic languages, but a negated universal quantifier can only be stranded in the Germanic languages. The goal of this paper is to show that this contrast between the Romance and the Germanic languages can be explained if one adapts the theory of sentential negation in Zeijlstra (2004) to constituent (quantifier) negation. According to Zeijlstra’s theor...

Diabetes and onset of natural menopause: results from the European Prospective Investigation into Cancer and Nutrition.

Science.gov (United States)

Brand, J S; Onland-Moret, N C; Eijkemans, M J C; Tjønneland, A; Roswall, N; Overvad, K; Fagherazzi, G; Clavel-Chapelon, F; Dossus, L; Lukanova, A; Grote, V; Bergmann, M M; Boeing, H; Trichopoulou, A; Tzivoglou, M; Trichopoulos, D; Grioni, S; Mattiello, A; Masala, G; Tumino, R; Vineis, P; Bueno-de-Mesquita, H B; Weiderpass, E; Redondo, M L; Sánchez, M J; Castaño, J M Huerta; Arriola, L; Ardanaz, E; Duell, E J; Rolandsson, O; Franks, P W; Butt, S; Nilsson, P; Khaw, K T; Wareham, N; Travis, R; Romieu, I; Gunter, M J; Riboli, E; van der Schouw, Y T

2015-06-01

Do women who have diabetes before menopause have their menopause at an earlier age compared with women without diabetes? Although there was no overall association between diabetes and age at menopause, our study suggests that early-onset diabetes may accelerate menopause. Today, more women of childbearing age are being diagnosed with diabetes, but little is known about the impact of diabetes on reproductive health. We investigated the impact of diabetes on age at natural menopause (ANM) in 258 898 women from the European Prospective Investigation into Cancer and Nutrition (EPIC), enrolled between 1992 and 2000. Determinant and outcome information was obtained through questionnaires. Time-dependent Cox regression analyses were used to estimate the associations of diabetes and age at diabetes diagnosis with ANM, stratified by center and adjusted for age, smoking, reproductive and diabetes risk factors and with age from birth to menopause or censoring as the underlying time scale. Overall, no association between diabetes and ANM was found (hazard ratio (HR) = 0.94; 95% confidence interval (CI) 0.89-1.01). However, women with diabetes before the age of 20 years had an earlier menopause (10-20 years: HR = 1.43; 95% CI 1.02-2.01, France); German Cancer Aid, German Cancer Research Center (DKFZ) and Federal Ministry of Education and Research (BMMF) (Germany); Ministry of Health and Social Solidarity, Stavros Niarchos Foundation and Hellenic Health Foundation (Greece); Italian Association for Research on Cancer (AIRC) and National Research Council (Italy); Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), Statistics Netherlands (The Netherlands); ERC-2009-AdG 232997 and Nordforsk, Nordic Centre of Excellence programme on Food, Nutrition and Health (Norway); Health Research Fund (FIS), Regional Governments of Andaluc

Creating a German–Basque Electronic Dictionary for German ...

African Journals Online (AJOL)

user

For German as a foreign language, the first text book written in German ..... In GFL production, it is often not the meaning but the syntactic properties ..... Hacia la creación de un corpus digitalizado, paralelo, trilingüe (alemán–español– uuskera) ...

The German Economy and U.S.-German Economic Relations

Science.gov (United States)

2009-11-30

Should the SPD and The Left overcome existing differences, the grouping could represent a leftward shift in German politics. Alliance ’90 / The...and replaced it with less generous social assistance benefits already available to poor individuals, regardless of employment history . These changes...director at Volkswagen . 48Hans-Werner Sinn, Can Germany Be Saved?, p. 108. 49 Alister Miskimmon and Walter E. Paterson, “Conclusion: coping with the

Breast Cancer -- Male

Science.gov (United States)

... Home > Types of Cancer > Breast Cancer in Men Breast Cancer in Men This is Cancer.Net’s Guide to Breast Cancer in Men. Use the menu below to choose ... social workers, and patient advocates. Cancer.Net Guide Breast Cancer in Men Introduction Statistics Risk Factors and Prevention ...

[Causes of death of German refugee children in 1945].

Science.gov (United States)

Lylloff, K

2000-02-28

In the last months of the second World War, 250,000 German refugees landed in Denmark. A third of them were children under the age of 15. Seven thousand German refugee children under the age of five died in Denmark in 1945. Using birth certificates and death certificates from the Danish national archives and burial lists from the German refugee cemetaries I have collected data to reveal causes of death, age distributions and time of the deaths of the 7000 fatal cases among children under the age of five. Three thousand children under the age of one, 2000 children one year old and 2000 children 2-4 years old died. Most of them died just before and after the German surrender, but many died in the months following the German surrender. The infant mortality was extremely high all during 1945. The infants died from diseases due to malnutrition, but the older the children the more likely the causes of death were due to infectious diseases such as pneumonia, measles, diphtheria and gastroenteritis.

The French-German initiative for Chernobyl: Overview of the French-German initiative

Energy Technology Data Exchange (ETDEWEB)

Biesold, H.; Friederichs, H.G.; Pretzsch, G. [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Dept. International Programmes, Berlin (Germany); Deville-Cavelin, G.; Lhomme, V.; Rutschkowsky, N.; Tirmarche, M. [Institut de Radioprotection et de Surete Nucleaire (IRSN), Dept. International Relations, 92 - Clamart (France); Bazyka, D.; Chabanyuk, V.; Seleznev, A. [Chornobyl Center (CC), Kiev regoin (Ukraine); Kellerer, A.M. [Munchen Univ., Strahlenbiologisches Institut (Germany)

2006-07-01

- Purpose: The main purpose of the French-German Initiative is to assist in the collection and validation of the existing data in Ukraine, Belarus and Russia for developing a reliable and objective basis useful for the planning of counter-measures, for information of the public, and for future work. - Coordination: GRS (Gesellschaft fuer Anlagen- und Reaktorsicherheit), supported in programme 3 by SBI (Strahlenbiologisches Institut der Universitaet Muenchen) and IRSN (Institut de radioprotection et de surete nucleaire) are coordinating the projects on the Western side. The CC (Chernobyl Center for Nuclear Safety, Radioactive Waste and Radioecology) as Eastern coordinator is also the beneficiary. German Support by Bundesministerium fuer Umwelt, Naturschutz und Reaktorsicherheit (BMU), Vereinigung Deutscher Elektrizitaetswerke (VDEW) e.V.; French Support by Institut de radioprotection et de surete nucleaire (IRSN), Electricite de France (EdF). - Programmes: Three scientific and technical co-operation programmes are financed with a total budget of about 6 million Euro within the frame work of the French- German Initiative: Programme 1: SARCOPHAGUS: Safety of the Chernobyl 'Sarcophagus', Programme 2: RADIOECOLOGY: Study of the radioecological consequences of the accident,Programme 3: HEALTH: Study of health effects. - Background: At the IAEA conference in Vienna in April 1996 - 10 years after the Chernobyl accident - the French and German Environment Ministers jointly announced their co-operation initiative with the Ukraine, Belarus and Russia over scientific programmes concerning the aftermath of the Chernobyl disaster. Numerous scientific studies have been conducted in the affected republics of the former USSR with and without the participation of international organisations, but largely with insufficient real co-ordination. For some of the studies, results have never been publicly documented. There are still incoherent or even contradictory reports on the

Axillary staging for breast cancer during pregnancy

DEFF Research Database (Denmark)

Han, S N; Amant, F; Cardonick, E H

2018-01-01

BACKGROUND: Safety of sentinel lymph node (SLN) biopsy for breast cancer during pregnancy is insufficiently explored. We investigated efficacy and local recurrence rate in a large series of pregnant patients. PATIENTS AND METHODS: Women diagnosed with breast cancer who underwent SLN biopsy during...... pregnancy were identified from the International Network on Cancer, Infertility and Pregnancy, the German Breast Group, and the Cancer and Pregnancy Registry. Chart review was performed to record technique and outcome of SLN biopsy, locoregional and distant recurrence, and survival. RESULTS: We identified...... were alive and free of disease. Eleven patients experienced a locoregional relapse, including 1 isolated ipsilateral axillary recurrence (0.7%). Eleven (7.6%) patients developed distant metastases, of whom 9 (6.2%) died of breast cancer. No neonatal adverse events related to SLN procedure during...

HIGHER CHOREOGRAPHIC EDUCATION: THE EXPERIENCE OF GERMAN-SPEAKING COUNTRIES

Directory of Open Access Journals (Sweden)

Iryna Tkachenko

2017-03-01

Full Text Available The current state of higher choreographic education and features of professional training of choreographers in the German-speaking countries, in particular Austria, Germany and Switzerland were analyzed. It is found that most of the German-speaking countries are Germany, Austria and Switzerland, which became the object of study. The considered the structure of higher choreographic education in the German-speaking countries. Universities, higher dance schools and higher art schools are functioning in Germany. Universities and academies are functioning in Austria and Switzerland. The institutions of theatre sciences, faculty of pedagogy and psychology, departments of performing arts are the structural units of the universities. The institutions of higher education have both private and state ownership. It is found out that the main areas for which training is future choreographers in the German-speaking countries there is a "Dance", "Dance pedagogy", "Modern dance", "Science of dance", "Choreography". German-speaking countries recognized by the training of specialists in the specialty choreography of Modern dance that has no analogues in Ukraine. The term of study is four (bachelor and two (master years. Higher choreographic education in these countries has a different approach and aims at mastering a separate specialty that provides future dance instructors completely and thoroughly master the basic knowledge and skills in this specialty. Specific conditions and rules of admission to the higher educational institutions of German-speaking countries.

German 450: Introduction to Business Operations in Germany. Initiating the Integration Process into the International Business Environment for German Majors at the Undergraduate and Graduate Levels.

Science.gov (United States)

Becker, Claudia A.

The redesign of a course on German business, taught at the University of Illinois at Chicago, is described. The course, intended for both undergraduate and graduate German majors, initially described and defined German institutions and common business practices and explored differences in historical and cultural backgrounds. Course revision…

Why Do German Men Marry Women from Less Developed Countries? An Analysis of Transnational Partner Search Based on the German Socio-Economic Panel

OpenAIRE

Glowsky, David

2007-01-01

This paper examines why German men marry women from countries which are less economically developed. Two hypotheses deduced from exchange theory and the economic theory of the family are tested: 1. Low physical and social attractiveness as well as reduced opportunities to meet German partners lead to marriage with a woman from a poorer country. 2. Because of the economic gap between their countries of origin, German men can marry comparatively more attractive women on the international marria...

Political Education in the Former German Democratic Republic.

Science.gov (United States)

Dumas, Wayne; Dumas, Alesia

1996-01-01

Investigates civic education curricular reform in the former German Democratic Republic (GDR). Discusses the problems inherent in reforming an entire educational system, from textbooks to teachers, originally designed for Marxist-Leninist purposes. Examines the German state educational structure and the role that the main political parties play in…

The Use of Film in Teaching German Culture

Science.gov (United States)

Figge, Richard C.

1977-01-01

Some of the possibilities of teaching German culture through the medium of the fictional film are suggested. Brief descriptions are provided of German films found useful in communicating some aspect or problem of twentieth-century culture. A select bibliography of works containing extensive analyses and interpretations is provided. (SW)

Great Britain and German-Polish Relations, 1929–1931

Directory of Open Access Journals (Sweden)

Zotova Ekaterina

2014-12-01

Full Text Available The article deals with the study of British-German relations during the period of exacerbation of territorial disputes between Germany and Poland in 1929-1931. Germany was making plans for revising the eastern borders. It sought to enlist the support of the new Labour government. Britain didn’t only approve of Germany's intention to carry out revision of the Treaty of Versailles (reparation issue, the evacuation of the Rhineland and the change in the German-Polish border, but also supported the strengthening of the political and economic situation in Germany as a whole. Assistance to Germany was advantageous for Britain. Firstly, the British support helped to improve the capacity of the purchasing power of the German market as one of the traditional markets of the English sale. Secondly, the strengthening of the position of the German cabinet meant failure of the French policy in Europe at this stage. The defeat of France in a dispute on the issue of early evacuation of the Rhineland would seriously devalue the foreign policy initiatives of Paris. Thirdly, the British government hoped that Germany will go into orbit of British political influence. The identity of the positions of the German and the British cabinets were considered as the components of British policy success not only in relations with France and Italy, but also with Czechoslovakia and Poland. Since the formation of the MacDonald’s cabinet, anti-Polish moods increased in the British course for the settlement of German-Polish relations. However, the threat of an attack on Poland by Germany was regarded by the government of Britain as unacceptable way of resolving the German-Polish conflict. Britain tried to follow the traditional foreign policy concept of “balance of power”, but the inefficiency of British policy “mediation” in European affairs was clearly shown in times of growing financial and economic crisis. The issue of the German-Polish border remained unsolved.

Industry 4.0: The Digital German Ideology

Directory of Open Access Journals (Sweden)

Christian Fuchs

2018-02-01

Full Text Available Especially in Germany, a vivid public debate about “industry 4.0” has developed in recent years. It advances the argument that industry 4.0 is the fourth industrial revolution that follows on from technological revolutions brought about by water and steam power (industrial revolution 1.0, electric power (industrial revolution 2.0, and computing/computerised automation (industrial revolution 3.0. In 1845/46, Marx and Engels wrote The German Ideology. 170 years later, we live in the time of digital capitalism that has its own peculiar forms of ideology. This paper argues that “industry 4.0” is the new German ideology, the digital German ideology. Image: By ChristophRoser, AllAboutLean.com, CC BY-SA 4.0, via Wikimedia Commons

Safety and safeguards aspects on retrievability: A German study

International Nuclear Information System (INIS)

Biurrun, E.; Engelmann, H.-J.; Brennecke, P.; Kranz, H.

2000-01-01

The article refers shortly to the definition of the term 'retrievability' and shows two different possibilities of retrieval scenarios, their advantages and detriments. The second part lists the Safeguards aspects of retrievability, gives a short outlook on the present German Safeguards Reference Concept in the post-closure phase of a repository in a salt dome and about the results of German studies concerning some proposed Safeguards methods. Furthermore, Planned investigations on Safeguards in the post-closure phase of a repository are mentioned. The third and main part finally describes the results of the German Retrievability Study, which was elaborated in the middle of the nineties by DBE on behalf of the German Federal Ministry of Education, Science, Research and Technology, BMBF, under an R and D contract. (author)

Current cancer research. Reports from the German Cancer Research Center 1998; Krebsforschung heute. Berichte aus dem Deutschen Krebsforschungszentrum 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-12-31

Topics from the Contents: The Fight against Cancer in Germany - A Critical Review. Conditions and Structures in Research. Familial Breast Cancer - A Critical Assessment. Research without Animal Experiments. Cancer Prevention. New Approaches for Tumor Therapy. Genes, Chromosomes and Cancer. Therapy of Brain Tumors with Laser Neurosurgery. The Genome Project. (orig.) [Deutsch] Krebsbekaempfung in Deutschland - kritische Ueberlegungen. Forschungsbedingungen und -strukturen. Forschung ohne Tierversuche. Familiaerer Brustkrebs - eine Risikoabschaetzung. Krebspraevention. Neue Therapieansaetze. Laser-Neurochirurgie bei Hirntumoren. Das Genomprojekt. Gene, Chromosomen und Krebs. (orig.)

THE PLIGHT OF GERMAN MISSIONS IN MANDATE CAMEROON: AN HISTORICAL ANALYSIS

Directory of Open Access Journals (Sweden)

Lang Michael Kpughe

2017-09-01

Full Text Available The First World War and its resultant Mandate and Trusteeship systems greatly affected the German mission enterprise in Cameroon. Apart from causing the forceful ousting of German missionaries from Cameroon, the British and the French whom the League of Nations and United Nations successively chose as administering powers within the Mandate and Trusteeship frameworks adopted hostile policies towards German missions. From the beginning of the war to the post-Second World War era, the foundation of German missions was seriously threatened. This paper critically examines the treatment of German missions in both British and French Cameroons during the Mandate and Trusteeship periods, focusing especially on the opposing attitudes of both administering powers towards the missions in their spheres of influence. The paper establishes that the administering powers’ treatment of German missions, which was underpinned by imperial and nationalist exigencies, roiled the attainment of the triple missionization agenda of planting self-supporting, self-governing and self-evangelizing churches. It thus argues that the First World War triggered the mistreatment of German missions, with some missions forced to terminate their activities while others were allowed to continue their mission work under difficult conditions.

'Good Hunting': German submarine offensives and South African ...

African Journals Online (AJOL)

By the latter half of 1942, the High Command of the German U-boats (BdU) realised that the 'sinking results' of the North Atlantic had decreased immensely. The successes of the Allied anti-submarine operations in the North Atlantic precluded the successful employment of the German submarines in said waters.

Skin Cancer Foundation

Science.gov (United States)

... Host a Fundraising Event | About Us | Store The Skin Cancer Foundation The Skin Cancer Foundation is the ... Handbook A "Sunscreen Gene"? Skin Cancer Facts & Statistics Skin Cancer Treatment Glossary Information on medications and procedures ...

German Registry for Acute Aortic Dissection Type A (GERAADA)--new software design, parameters and their definitions.

Science.gov (United States)

Weigang, E; Görgen, C; Kallenbach, K; Dapunt, O; Karck, M

2011-03-01

The working group for aortic surgery and interventional vascular surgery of the German Society for Thoracic and Cardiovascular Surgery (GSTCVS) initiated the web-based German Registry for Acute Aortic Dissection type A (GERAADA). It is the project's aim to collect standardized data from a large pool of patients with acute aortic dissections type A (AADA) to gain a deeper insight and knowledge to improve surgical therapies and perioperative management for these patients in the future. In addition to new medical insights, the working group has gained more experience over the last 4 years in how to collect valid and high-quality data. This experience led us to revise the database completely. In this article we describe the new version of GERAADA, providing an overview as well as defining the parameters, and explaining the new features. This overview fulfills a request by the users of GERAADA in the participating centers. Since its inception, 50 cardiac centers in Germany, Austria and Switzerland have provided over 2000 records and the first statistical results have been published. GERAADA's new design allows it to stay abreast of changes in medicine and to focus on the essentials necessary for statistically relevant results, while keeping the work load low for the data providers at each cardiac center. © Georg Thieme Verlag KG Stuttgart · New York.

Intransparent German number words complicate transcoding - a translingual comparison with Japanese.

Science.gov (United States)

Moeller, Korbinian; Zuber, Julia; Olsen, Naoko; Nuerk, Hans-Christoph; Willmes, Klaus

2015-01-01

Superior early numerical competencies of children in several Asian countries have (amongst others) been attributed to the higher transparency of their number word systems. Here, we directly investigated this claim by evaluating whether Japanese children's transcoding performance when writing numbers to dictation (e.g., "twenty five" → 25) was less error prone than that of German-speaking children - both in general as well as when considering language-specific attributes of the German number word system such as the inversion property, in particular. In line with this hypothesis we observed that German-speaking children committed more transcoding errors in general than their Japanese peers. Moreover, their error pattern reflected the specific inversion intransparency of the German number-word system. Inversion errors in transcoding represented the most prominent error category in German-speaking children, but were almost absent in Japanese-speaking children. We conclude that the less transparent German number-word system complicates the acquisition of the correspondence between symbolic Arabic numbers and their respective verbal number words.

German Foreign Fighters in Syria and Iraq

Science.gov (United States)

2016-03-01

depressed and less integrated into their new societies.29 Germany’s Turkish population exemplifies this integration deficit. Of Germany’s 4.3 million...the German Chancellor in a YouTube video, for example), the German press tends to abandon their earlier self-restraint and freely publishes the...Germany’s most well-known Salafist preachers. In addition to being mentored by Pierre Vogel, Cuspert appeared in YouTube recordings at Islam

German power options: Lack of clarity will be costly

International Nuclear Information System (INIS)

Schuelke, Christian

2010-01-01

The German environment minister Norbert Roettgen (CDU) revived the German debate about the future of nuclear power in February when he argued for a limited lifetime extension of Germany's nuclear plants. His statements created much dissent in his own party and with the coalition partner FDP. The government will not take a formal decision before the autumn, but the contradicting messages from inside the government send highly ambiguous signals to electricity utilities with investment plans in Germany. What does the German government want the companies to do?

German genes and Turkish traits: ethnicity, infertility, and reproductive politics in Germany.

Science.gov (United States)

Vanderlinden, Lisa K

2009-07-01

This ethnographic study uses the lens of ethnic difference to examine the experience of infertility and the cultural politics of belonging in modern Germany. The data are derived from participant observation and interviews conducted with forty-one ethnic Germans and thirty-three German Turks undergoing biomedical treatment for infertility at a fertility clinic in Berlin (1998-2000). Through their illness narratives, men and women symbolically link their loss of biological parenthood to losses in other life arenas, such as gender identity, social status and cultural acceptance. Results reveal that while both German Turks and ethnic Germans experience disruption and social suffering from their inability to conform to procreative norms, German Turkish sufferers exhibit higher levels of distress, which directly relates to their dual stigma as outsiders in both German Turkish culture and mainstream German culture. The findings suggest that the tensions surrounding individual reproductive practices are reflective of larger national tensions regarding the constitution of the body politic in an increasingly multicultural Germany.

Structure of the German electricity industry

International Nuclear Information System (INIS)

1992-01-01

The German integrated association is a union of those electric power supply utilities in the Federal Republic of Germany which cooperate in the integrated operation of 220 kV and 380 kV. The German integrated association (DVG) was founded in 1948. Its main task is to create the technical, operational and legal conditions for the cooperation in the national and international integrated system. The inclusion of the new Federal States has been practiced for the first time with the 320 MW power station in Offleben. (DG) [de

Statistical and Multidimensional Body Composition Parameter Analysis in Young Childhood Cancer Survivors

Directory of Open Access Journals (Sweden)

Topczewska Magdalena

2014-12-01

Full Text Available This article concerns the problem of assessing selected body compo- sition parameters after completion of antitumor therapy and comparing them with the same parameters of healthy children. A high percentage of overweight and obesity, as well as abnormal fat distribution in convalescents with cancer shows a significant adverse effect of therapy on body composition and suggests the need for early intervention in terms of diet and exercise, which would help patients to quickly achieve the proper parameters of body composition. Two main problems will be mentioned during the presented data analysis. Firstly, in each group there was a small number of observations. Because of this, the real differences between examined subgroups may have been omitted. Secondarily, many variables are correlated and are not normally distributed. Therefore, be- side the standard statistical tests to compare two groups, principal component analysis was applied to reduce the dimensions of the attribute space and to attempt to classify two groups of patients.

Latest German-English Terminology in CADCAM and Robotics

International Nuclear Information System (INIS)

Hussain, S M

2014-01-01

As a technical translator who speaks German fluently, the author would like to study and display the latest bilingual technical terminology in German being used in hardware, software and process technology involved in CADCAM and ROBOTICS. This will greatly help technical translators to correctly translate difficult texts from this area of technology

An empirical analysis of the German interest rate

NARCIS (Netherlands)

den Butter, F.A.G.; Jansen, P.W.

2004-01-01

The short run and long run influences of the main determinants of the German long-term interest rate are estimated using quarterly data for the period 1982-2001. A major reason for the focus on the German interest rate is that this rate, and hence its determinants, will be dominant in explaining the

ECONOMIC ASPECTS OF RUSSIAN-GERMAN RELATIONS IN 2000-2013

Directory of Open Access Journals (Sweden)

Юлия Олеговна Пучинская

2016-12-01

Full Text Available The effective collaboration between the Russian Federation and Germany at the beginning of the 21st century would be impossible without mutually beneficial economic cooperation of the two countries. The analysis of basic stages in the economic relations, achievements and problems are considered by the author to be important for lining-up an all-round picture of the Russian-German relations in the period under review. The main purpose of this article is the consideration and analysis of the economic aspects in the Russian foreign policy towards Germany. The problem considered in the article is of current importance, because in 2000-2013 the economic collaboration of Russia and the German Federal Republic was brought to a high level, but at the same time some considerable potential of cooperation was not fulfilled. With regard to complementarity of the Russian and German economies and their centuries-old experience of collaboration and mutual financial interest, it is possible to suppose that the economic sphere in particular would be a basis of optimization of the Russian-German relations in the long term. In such a way, this article deals with the basic directions of the Russian-German economic cooperation in 2000-2013.The contractual legal base of financial relations is examined with the purpose to reveal strengths and weaknesses as well as perspective possibilities of the optimization in the Russian-German relations in the future.

Heisenberg's war. The secret history of the German bomb

International Nuclear Information System (INIS)

Powers, T.

1993-01-01

The history of Second World War Germany's 'Uranium Project', which often is referred to as the 'myth of the German atomic bomb', has been attracting the mind's of secret service men, futurologists, historians and journalists since after the end of the war it has become possible to lift the veil of secrecy. Powers book adds another one to the many investigations published since them. His approach to the piece of history starts with Heisenberg's visit to the U.S.A. in summer 1939, describes the plans of the German Heereswaffenamt pursued with the Uranium Project, and their counterpart on the side of the Allied Forces where German scientists, as immigrants in England and in the U.S.A., were doing their best to launch research for the development of an atomic bomb. The end of this 'competition' is marked by the internment of the ten German scientists and bomb specialists in Fall Hall. The leading story of the book centers on the small group of scientists around Heisenberg, who cleverly 'torpedoed' the development of the German atomic bomb in the years from 1939 until 1944. (HP) [de

Revitalization of ethnic identity among the Germans in Sremski Karlovci

Directory of Open Access Journals (Sweden)

Krel Aleksandar

2009-01-01

Full Text Available During the 1990's, many members of the German national minority have awaken from the several decades long sleep in 'ethnic hibernation'. Several associations have been founded at that time, with an aim to gather and encourage ethnic feelings of the Germans living in Vojvodina. These associations work toward revitalization and reconstruction of the German ethnic and cultural identity. There are quite a few of such institutions today, and one of them is German association promoting good neighbor relations Karlowitz, Sremski Karlovci. This paper will discuss transformation of an ethnic identity strategy among the Germans in Sremski Karlovci; in addition, I will analyze modus operandi by which this local association aims at keeping and encouraging certain elements of the ethnic and cultural particulars. The results of the research point out how a relatively small group, without social power, can define and redefine its own identity, in regards to historical, social and economic conditions.

Abridged version of the AWMF guideline for the medical clinical diagnostics of indoor mould exposure: S2K Guideline of the German Society of Hygiene, Environmental Medicine and Preventive Medicine (GHUP) in collaboration with the German Association of Allergists (AeDA), the German Society of Dermatology (DDG), the German Society for Allergology and Clinical Immunology (DGAKI), the German Society for Occupational and Environmental Medicine (DGAUM), the German Society for Hospital Hygiene (DGKH), the German Society for Pneumology and Respiratory Medicine (DGP), the German Mycological Society (DMykG), the Society for Pediatric Allergology and Environmental Medicine (GPA), the German Federal Association of Pediatric Pneumology (BAPP), and the Austrian Society for Medical Mycology (ÖGMM).

Science.gov (United States)

Wiesmüller, Gerhard A; Heinzow, Birger; Aurbach, Ute; Bergmann, Karl-Christian; Bufe, Albrecht; Buzina, Walter; Cornely, Oliver A; Engelhart, Steffen; Fischer, Guido; Gabrio, Thomas; Heinz, Werner; Herr, Caroline E W; Kleine-Tebbe, Jörg; Klimek, Ludger; Köberle, Martin; Lichtnecker, Herbert; Lob-Corzilius, Thomas; Merget, Rolf; Mülleneisen, Norbert; Nowak, Dennis; Rabe, Uta; Raulf, Monika; Seidl, Hans Peter; Steiß, Jens-Oliver; Szewszyk, Regine; Thomas, Peter; Valtanen, Kerttu; Hurraß, Julia

2017-01-01

This article is an abridged version of the AWMF mould guideline "Medical clinical diagnostics of indoor mould exposure" presented in April 2016 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine ( Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP ), in collaboration with the above-mentioned scientific medical societies, German and Austrian societies, medical associations and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established. Apart from allergic bronchopulmonary aspergillosis (ABPA) and mould-caused mycoses, only sufficient evidence for an association between moisture/mould damage and the following health effects has been established: allergic respiratory disease, asthma (manifestation, progression and exacerbation), allergic rhinitis, hypersensitivity pneumonitis (extrinsic allergic alveolitis), and increased likelihood of respiratory infections/bronchitis. In this context the sensitizing potential of moulds is obviously low compared to other environmental allergens. Recent studies show a comparatively low sensitizing prevalence of 3-10% in the general population across Europe. Limited or suspected evidence for an association exist with respect to mucous membrane irritation and atopic eczema (manifestation, progression and exacerbation). Inadequate or insufficient evidence for an association exist for chronic obstructive pulmonary disease, acute idiopathic pulmonary hemorrhage in children, rheumatism/arthritis, sarcoidosis and cancer. The risk of infection posed by moulds regularly occurring indoors is low for healthy persons; most species are in risk group 1 and a few in risk group 2 ( Aspergillus fumigatus, A. flavus ) of the German Biological Agents Act ( Biostoffverordnung ). Only moulds that are potentially able to form toxins can be triggers of toxic

Statistical Analysis of the Impact of Wind Power on Market Quantities and Power Flows

DEFF Research Database (Denmark)

Pinson, Pierre; Jónsson, Tryggvi; Zugno, Marco

2012-01-01

In view of the increasing penetration of wind power in a number of power systems and markets worldwide, we discuss some of the impacts that wind energy may have on market quantities and cross-border power flows. These impacts are uncovered through statistical analyses of actual market and flow data...... of load and wind power forecasts on Danish and German electricity markets....

The development by the German Transactional Analysis Association of a scientifically-based online evaluation system of transactional analysis training

Directory of Open Access Journals (Sweden)

Norbert Nagel

2017-07-01

Full Text Available The authors present the development and statistical analysis, conducted under the auspices of the German Transactional Analysis Association (DGTA, of an online evaluation system of transactional analysis training.  The understanding of evaluation research is clarified, and the data-entry form and its grounding in the theory of transactional analysis are presented. Emphasis is placed on the development of the competence concept, the definition of competence categories, and the representation of the foundations of a transactional-analytic educational theory.  The scientific examination of the validity and reliability of the scales, the research process with pre-test and re-test, and the evaluation of the data in the system of online evaluation are extensively documented.  In conclusion, it is claimed that this online-based DGTA evaluation is one of the few result-oriented teaching evaluation instruments in the German-speaking countries which meets scientific control criteria and is published. Citation - APA format: Nagel, N., König, J., Ottmann, S., & Hahnle, A. (2017. The development by the German Transactional Analysis Association of a scientifically-based online evaluation system of transactional analysis training. International Journal of Transactional Analysis Research & Practice, 8(2, 3-23.

The Social Stratification of the German VET System

Science.gov (United States)

Protsch, Paula; Solga, Heike

2016-01-01

Germany is widely known for its vocational education and training (VET) system and its dual apprenticeship system in particular. What is often overlooked, however, is the vertical stratification within the German VET system. This is the focus of this study. Our analysis shows that the VET system, like the German school system, is highly…

Education and employment in patients with juvenile idiopathic arthritis - a standardized comparison to the German general population.

Science.gov (United States)

Schlichtiger, Jenny; Haas, Johannes-Peter; Barth, Swaantje; Bisdorff, Betty; Hager, Lisa; Michels, Hartmut; Hügle, Boris; Radon, Katja

2017-05-22

Although several studies show that JIA-patients have significantly lower employment rates than the general population, the research on educational and occupational attainments in patients with juvenile idiopathic arthritis (JIA) remain conflicting most likely due to small sample sizes. Therefore, aim of this study is to compare the educational achievements and employment status of 3698 JIA-patients with the German general population (GGP). "SEPIA" was a large cross-sectional study on the current status of a historic cohort of JIA-patients treated in a single center between 1952 and 2010. For the analyses of education and employment a sub-cohort was extracted, including only adult cases with a confirmed diagnosis of JIA (N = 2696). Participants were asked to fill out a standardized written questionnaire on education and employment. Outcome measures (education/unemployment) were directly standardized to the GGP using data obtained from the National Educational Panel Study 2013 (N = 11,728) and the German Unemployment Statistics 2012 of the Federal Statistical Office (N = 42,791,000). After age- and sex-standardization, 3% (95% Confidence Interval 1.9 to 4.1%) more of the JIA-patients (26%) than of the GGP (23%) had only reached primary education. In contrast, parents of JIA-patients had similar levels of education as parents in the GGP. With a standardized difference of 0.2% (95% CI: 0.16 to 0.19%), the unemployment rate in JIA-patients was slightly, but not significantly higher than in the GGP. Stratifying for disease duration and the current treatment status, differences were confirmed for persons diagnosed before 2001, whilst for patients diagnosed after 2000, differences were found only in JIA-patients with ongoing disease. Medium and high educational achievements did not differ statistically significant between JIA patients and the GPP. Educational achievements in German JIA-patients are significantly lower than in the GGP. Furthermore we were able to

Vestibular morphology in the German Waltzing guinea pig.

Science.gov (United States)

Kawaguchi, Sachie; Hultcrantz, Malou; Jin, Zhe; Ulfendahl, Mats; Suzuki, Mamoru

2010-04-01

The German waltzing guinea pig is a special strain of animal with a recessively inherited inner ear defect, resulting in deafness and a severe vestibular dysfunction. The hearing loss in the cochlea of the German strain is a result of a collapse of the Reissner membrane and the absence of scala media. The vestibular organ has not yet been described. German waltzing guinea pigs (homozygote and heterozygote) of different ages ranging from embryologic age 25 days to adulthood were investigated. The living animals were tested with four different vestibular tests, and the fetuses were controlled according to breeding. The morphology of the vestibular parts (ampulla, saccule, and utricle) was observed by using the light and transmission electron microscopy. Collapse of the membranous labyrinth was found already at embryologic age 50 days and progressed over time. Vestibular dysfunction was noted already from birth. Vestibular atelectasis has been shown to have the same morphology as the reported vestibular dysfunction in the German waltzing guinea pig. Owing to this similarity, this animal can be a good model for vestibular research.

Annual report 1993 of the German Atomic Forum

International Nuclear Information System (INIS)

Petroll, M.

1994-01-01

In retrospect it is stated that in 1993 the hopes of an energy policy consensus between the political parties have not come true; the operation of existing plants continues to be politically endangered, and the future of nuclear energy continues to be unclear. Particularly depressing is the large number of nuclear installations whose fate is undecided. To save German industry from serious harm, an energy policy consensus has to be found which the German Atomic Forum seeks to bring about. An account is given of organized events and working groups, of international cooperation and cooperation with other organizations. In 1993 German nuclear power plants generated more than 153,5 thousand million kilowatt-hours, thus contributing, as the year before, more than one third (34%) to power supply. In Western Germany this percentage even amounted to almost 40%. The use of nuclear energy made it possible in 1993 to avoid release of more than 150 million tons of carbon dioxide, that is about 15% of German overall emissions. (orig./HSCH) [de

On the intonation of German intonation questions

DEFF Research Database (Denmark)

Petrone, Caterina; Niebuhr, Oliver

2014-01-01

German questions and statements are distinguished not only by lexical and syntactic but also by intonational means. This study revisits, for Northern Standard German, how questions are signalled intonationally in utterances that have neither lexical nor syntactic cues. Starting from natural......, but represents a separate attitudinal meaning dimension. Moreover, the findings support that both prenuclear and nuclear fundamental frequency (F0) patterns must be taken into account in the analysis of tune meaning....

Univariate characterization of the German business cycle 1955-1994

OpenAIRE

Weihs, Claus; Garczarek, Ursula

2002-01-01

We present a descriptive analysis of stylized facts for the German business cycle. We demonstrate that simple ad-hoc instructions for identifying univariate rules characterizing the German business cycle 1955-1994 lead to an error rate comparable to standard multivariate methods.

Male suicide rates in German prisons and the role of citizenship.

Science.gov (United States)

Radeloff, Daniel; Lempp, Thomas; Kettner, Mattias; Rauf, Amna; Bennefeld-Kersten, Katharina; Freitag, Christine M

2017-01-01

Prisoners are at a particularly high risk of suicide. In contrast to other psychosocial risk factors it remains unclear to what degree the risk of suicide differs between prisoners with local citizenship and foreigners. In order to provide more detailed information for suicide prevention in prisons, this study aims to compare suicide rates (SR) between these populations in German criminal custody. Based on a German national database of completed suicide in custody, suicides by prisoners were analysed and compared with epidemiological data of the prison population and the general population, stratified for German and foreign citizenship. Data analysis was adjusted for differences in the age distribution of both populations by calculating standard mortality ratios (SMR) for suicide. SR were higher in prisoners with German citizenship than those with foreign citizenship (SR = 76.5 vs. SR = 42.8, Pcitizenship was comparable in juvenile and adult prisoners, indicating its relevance to both the juvenile and adult detention systems. Imprisonment is associated with a substantially increased risk of suicide in both German and non-German citizens, a finding which needs to be taken into consideration by the justice system. The lower suicide risk in non-German citizens is independent of whether or not they are in custody.

Male suicide rates in German prisons and the role of citizenship

Science.gov (United States)

Lempp, Thomas; Kettner, Mattias; Rauf, Amna; Bennefeld-Kersten, Katharina; Freitag, Christine M.

2017-01-01

Purpose Prisoners are at a particularly high risk of suicide. In contrast to other psychosocial risk factors it remains unclear to what degree the risk of suicide differs between prisoners with local citizenship and foreigners. In order to provide more detailed information for suicide prevention in prisons, this study aims to compare suicide rates (SR) between these populations in German criminal custody. Methods Based on a German national database of completed suicide in custody, suicides by prisoners were analysed and compared with epidemiological data of the prison population and the general population, stratified for German and foreign citizenship. Data analysis was adjusted for differences in the age distribution of both populations by calculating standard mortality ratios (SMR) for suicide. Results SR were higher in prisoners with German citizenship than those with foreign citizenship (SR = 76.5 vs. SR = 42.8, Pcitizenship was comparable in juvenile and adult prisoners, indicating its relevance to both the juvenile and adult detention systems. Conclusion Imprisonment is associated with a substantially increased risk of suicide in both German and non-German citizens, a finding which needs to be taken into consideration by the justice system. The lower suicide risk in non-German citizens is independent of whether or not they are in custody. PMID:28591187

Genesis and Evolution of the Romance-Germanic Language Border in Europe.

Science.gov (United States)

van Durme, Luc

2002-01-01

Discusses various language border theories for the Belgian-Northern French area, and summarizes the results of 40 years of research into the development of the Romance-Germanic language border at large. Suggests that a late Roman Latin-Germanic opposition has functioned as a direct predisposition for the early medieval Romance-Germanic language…

Retraining in Business German through the Goethe Institute in West Germany.

Science.gov (United States)

Clay, Gudrun; Schutte, Lilith

A college language instructor recounts his experience in a retraining program in business German at the West Germany's Goethe Institute. Twenty-eight individuals from the United States and from five European countries participated in a program that offered (1) a 14-day immersion into business-related German, (2) establishment of German business…

Oral cancer statistics in India on the basis of first report of 29 population-based cancer registries

Science.gov (United States)

Sharma, Swati; Satyanarayana, L; Asthana, Smitha; Shivalingesh, KK; Goutham, Bala Subramanya; Ramachandra, Sujatha

2018-01-01

Objectives: To summarize and provide an overview of age-specific oral cancer incidence reported in 29 population-based cancer registry in India. Materials and Methods: Secondary data on age-adjusted rates (AARs) of incidence of oral cancer and other associated sites for all ages (0–75 years) were collected from the report of the National Cancer Registry Programme 2012–2014 in 29 population-based control registries. Results: Among both males and females, mouth cancer had maximum Age adjusted incidence rates (64.8) in the central zone, while oropharynx cancer had minimum AAR (0) in all regions. Conclusion: Oral cancer incidence increases with age with typical pattern of cancer of associated sites of oral cavity seen in the northeast region. PMID:29731552

School of German Language

Directory of Open Access Journals (Sweden)

Sergei V. Evteev

2014-01-01

Full Text Available Department of German is one of the oldest language departments at MGIMO. Since its foundation in 1944 the military experienced teachers of the department, most of whom were native speakers, have begun to develop a unique method of teaching the German language, thereby revolutionize learning this foreign language. The first steps made under the supervision of the Department of Antonina V. Celica. The department refused to conventional time and is still used in universities such as the Moscow Linguistic University, separate teaching phonetics, grammar and vocabulary, which was due to the specific objectives set for the teaching staff: prepare for short term specialists in international relations, active Germanspeaking. The department can be proud of its graduates, many of whom continue his career in the walls of native high school. Many graduates have dedicated their lives to serving the State in the Ministry of Foreign Affairs.

Generational Aspects of German National Socialism, 1919-33.

Science.gov (United States)

Madden, Paul

1982-01-01

Examines the theory that pre-Hitler Nazism was part of a generational revolt. Research shows that, among new recruits to the National Socialist German Workers Party in that period, there were more than twice as many who were under 30 years old. Socioeconomic and historical factors which made Nazism attractive to German youth are discussed. (AM)

German Culture and Civilization, Foreign Language: 7536.14.

Science.gov (United States)

Dade County Public Schools, Miami, FL.

This is a guide to a realization and appreciation of the German culture, gained through the use of oral and written German. Four areas of language instruction are emphasized: (1) listening, (2) speaking, (3) reading, and (4) writing. The guide is divided into five sections: (1) broad goals and performance objectives, which include a breakdown of…

Optical Properties of Tm(3+) Ions in Alkali Germanate Glass

Science.gov (United States)

Walsh, Brian M.; Barnes, Norman P.; Reichle, Donald J.; Jiang, Shibin

2006-01-01

Tm-doped alkali germanate glass is investigated for use as a laser material. Spectroscopic investigations of bulk Tm-doped germanate glass are reported for the absorption, emission and luminescence decay. Tm:germanate shows promise as a fiber laser when pumped with 0.792 m diodes because of low phonon energies. Spectroscopic analysis indicates low nonradiative quenching and pulsed laser performance studies confirm this prediction by showing a quantum efficiency of 1.69.

Alexithymia in the German general population.

Science.gov (United States)

Franz, Matthias; Popp, Kerstin; Schaefer, Ralf; Sitte, Wolfgang; Schneider, Christine; Hardt, Jochen; Decker, Oliver; Braehler, Elmar

2008-01-01

The Toronto-Alexithymia-Scale (TAS-20) is used worldwide as a valid measurement of alexithymia. Until now, population-based standardization and cut-off values of the German TAS-20 version have not been available. This study provides these by means of a representative German sample and by investigating the factorial structure of the TAS-20. Data were generated from a representative random sample of the German general population (1,859 subjects aged between 20 and 69). The TAS-20 sum score was normally distributed. The mean value was 49.5 (SD=9.3) in men and 48.2 (SD=9.2) in women. Divorce, single and low social status were associated with enhanced sum scores. Ten percent of the population exceeded the TAS-20 sum score threshold of >or=61. The 66th percentile reached 53 for men and 52 for women. Factor analysis identified three factors that match the scales of the English original version. An additional fourth factor ("importance of emotional introspection") was extracted. Total explanation of variance by these four factors was 52.27%. The sum score of the German TAS-20 version is suited for the standardized measure of alexithymia. For selecting alexithymic individuals in experimental studies, the cut-off >or=61 is possibly too restrictive. Therefore, we propose the 66th percentile for the identification of high alexithymics. The TAS-20 sum score is associated with important socio-demographic variables. The factorial structure is reliable; the fourth factor ("importance of emotional introspection") provides differentiation of content and allows for enhanced explanation of variance.

Intransparent German number words complicate transcoding - A translingual comparison with Japanese

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Korbinian eMoeller

2015-06-01

Full Text Available Superior early numerical competencies of children in several Asian countries have (amongst others been attributed to the higher transparency of their number word systems. Here, we directly investigated this claim by evaluating whether Japanese children’s transcoding performance when writing numbers to dictation (e.g., twenty five  25 was less error prone than that of German-speaking children; both in general as well as when considering language-specific attributes of the German number word system such as the inversion property, in particular. In line with this hypothesis we observed that German-speaking children committed more transcoding errors in general than their Japanese peers. Moreover, their error pattern reflected the specific inversion intransparency of the German number-word system. Inversion errors in transcoding represented the most prominent error category in German-speaking children, but were almost absent in Japanese-speaking children. We conclude that the less transparent German number-word system complicates the acquisition of the correspondence between symbolic Arabic numbers and their respective verbal number words.

[German-Japanese scientific exchange in urology in the early 20th century].

Science.gov (United States)

Halling, T; Umehara, H; Moll, F

2014-01-01

This paper analyzes the importance of the German language and German culture and institutional development of urology in Japan in the early 20th century, starting from the development of the medical school for Japanese in Germany and their function in the process of modernization of the Meiji period (1868-1912). Examples of bi-directional German-Japanese relations in medicine, which also included an integrated knowledge transfer, are shown. The study is based mainly on Japanese and German sources about Japanese physicians in Germany as well as contemporary publications in German and international medical journals. Methodologically, the article combines quantitative analysis with individual biographical aspects.

Paleontology and Darwin's Theory of Evolution: The Subversive Role of Statistics at the End of the 19th Century.

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Tamborini, Marco

2015-11-01

This paper examines the subversive role of statistics paleontology at the end of the 19th and the beginning of the 20th centuries. In particular, I will focus on German paleontology and its relationship with statistics. I argue that in paleontology, the quantitative method was questioned and strongly limited by the first decade of the 20th century because, as its opponents noted, when the fossil record is treated statistically, it was found to generate results openly in conflict with the Darwinian theory of evolution. Essentially, statistics questions the gradual mode of evolution and the role of natural selection. The main objections to statistics were addressed during the meetings at the Kaiserlich-Königliche Geologische Reichsanstalt in Vienna in the 1880s. After having introduced the statistical treatment of the fossil record, I will use the works of Charles Léo Lesquereux (1806-1889), Joachim Barrande (1799-1833), and Henry Shaler Williams (1847-1918) to compare the objections raised in Vienna with how the statistical treatment of the data worked in practice. Furthermore, I will discuss the criticisms of Melchior Neumayr (1845-1890), one of the leading German opponents of statistical paleontology, to show why, and to what extent, statistics were questioned in Vienna. The final part of this paper considers what paleontologists can derive from a statistical notion of data: the necessity of opening a discussion about the completeness and nature of the paleontological data. The Vienna discussion about which method paleontologists should follow offers an interesting case study in order to understand the epistemic tensions within paleontology surrounding Darwin's theory as well as the variety of non-Darwinian alternatives that emerged from the statistical treatment of the fossil record at the end of the 19th century.

Assessing met and unmet needs in the oldest-old and psychometric properties of the German version of the Camberwell assessment of need for the elderly (CANE)--a pilot study.

Science.gov (United States)

Stein, Janine; Luppa, Melanie; König, Hans-Helmut; Riedel-Heller, Steffi G

2014-02-01

The current demographic and social developments in our society will lead to a significant increase in treatment and healthcare needs in the future, particularly in the elderly population. The Camberwell Assessment of Need for the Elderly (CANE) was developed in the United Kingdom to measure physical-, psychological-, and environment-related treatment as well as healthcare needs of older people in order to identify their unmet needs. So far, the German version of the CANE has not been established in health services research. Major reasons for this are a lack of publications of CANE's German version and the missing validation of the instrument. The aims of the present study were to evaluate the currently available German version of the CANE in a sample of older primary care patients. Descriptive statistics and inference-statistical analyses were calculated. Patients reported unmet needs mostly in CANE's following sections: mobility/falls, physical health, continence, company, and intimate relationships. Agreement level between patients' and relatives' ratings in CANE was moderate to low. Evidence for the construct validity of CANE was found in terms of significant associations between CANE and other instruments or scores. The study results provide an important basis for studies aiming at the assessment of met and unmet needs in the elderly population. Using the German version of the CANE may substantially contribute to an effective and good-quality health and social care as well as an appropriate allocation of healthcare resources in the elderly population.

DEGRO practical guidelines for radiotherapy of breast cancer I. Breast-conserving therapy

International Nuclear Information System (INIS)

Sautter-Bihl, M.L.; Budach, W.; Dunst, J.; Feyer, P.; Haase, W.; Harms, W.; Sedlmayer, F.; Souchon, R.; Wenz, F.; Sauer, R.

2007-01-01

Background: The present paper is an update of the practical guidelines for radiotherapy of breast cancer published in 2006 by the breast cancer expert panel of the German Society of Radiation Oncology (DEGRO). These recommendations have been elaborated on the basis of the S3 guidelines of the German Cancer Society that were revised in March 2007 by an interdisciplinary panel. Methods: The DEGRO expert panel performed a comprehensive survey of the literature, comprising lately published meta-analyses, data from recent randomized trials and guidelines of international breast cancer societies, referring to the criteria of evidence-based medicine. In addition to the more general statements of the German Cancer Society, this paper emphasizes specific radiotherapeutic aspects. It is focused on radiotherapy after breast-conserving surgery. Technique, targeting, and dose are described in detail. Results: Postoperative radiotherapy significantly reduces rates of local recurrence. The more pronounced the achieved reduction is, the more substantially it translates into improved survival. Four prevented local recurrences result in one avoided breast cancer death. This effect is independent of age. An additional boost provides a further absolute risk reduction for local recurrence irrespective of age. Women > 50 years have a hazard ratio of 0.59 in favor of the boost. For DCIS, local recurrence was 2.4% per patient year even in a subgroup with favorable prognostic factors leading to premature closure of the respective study due to ethical reasons. For partial-breast irradiation as a sole method of radiotherapy, results are not yet mature enough to allow definite conclusions. Conclusion: After breast-conserving surgery, whole-breast irradiation remains the gold standard of treatment. The indication for boost irradiation should no longer be restricted to women ≤ 50 years. Partial-breast irradiation is still an experimental treatment and therefore discouraged outside controlled

On the contrast between Germanic and Romance negated quantifiers

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Robert Cirillo

2009-01-01

Full Text Available Universal quantifiers can be stranded in the manner described by Sportiche (1988, Giusti (1990 and Shlonsky (1991 in both the Romance and Germanic languages, but a negated universal quantifier can only be stranded in the Germanic languages. The goal of this paper is to show that this contrast between the Romance and the Germanic languages can be explained if one adapts the theory of sentential negation in Zeijlstra (2004 to constituent (quantifier negation. According to Zeijlstra’s theory, a negation marker in the Romance languages is the head of a NegP that dominates vP, whereas in the Germanic languages a negation marker is a maximal projection that occupies the specifier position of a verbal phrase. I will show that the non-occurrence of stranded negated quantifiers in the Romance languages follows from the fact that negation markers in the Romance languages are highly positioned syntactic heads.

'German Angst' vs 'Danish Easy Going'?

DEFF Research Database (Denmark)

Fersch, Barbara

2012-01-01

national lines. Whereas insecurity and its related fear and anxiety played a huge role in the German interviews (‘German Angst’), the Danish freelancers attached less importance to the topic of insecurity and showed almost no sign of related anxiety (‘Danish Easy-going’). Some reasons for this can be found...... in the different social security backgrounds and welfare state programmes of the two countries, but these differences cannot explain the very different ways of talking about and dealing with the topic. Therefore, I suggest that the differences can be understood in the context of trust as a multi...

German financial media's responsiveness to Deutsche Bank's cultural change

NARCIS (Netherlands)

Strauß, N.

2015-01-01

Based on first-order and second-order agenda building theory, this study analyzes the responsiveness of German financial media to frames of the "cultural change" proclaimed in the banking industry, exemplified by Deutsche Bank. Findings suggest a difference between the two major German financial

Cross-Linguistic Differences in Prosodic Cues to Syntactic Disambiguation in German and English

Science.gov (United States)

O'Brien, Mary Grantham; Jackson, Carrie N.; Gardner, Christine E.

2014-01-01

This study examined whether late-learning English-German second language (L2) learners and late-learning German-English L2 learners use prosodic cues to disambiguate temporarily ambiguous first language and L2 sentences during speech production. Experiments 1a and 1b showed that English-German L2 learners and German-English L2 learners used a…

German and Korean mothers' sensitivity and related parenting beliefs

Science.gov (United States)

Ziehm, Jeanette; Trommsdorff, Gisela; Heikamp, Tobias; Park, Seong-Yeon

2013-01-01

This study contributes to a differentiated understanding of maternal sensitivity in cultural and situational context. We investigated differences and similarities in German and Korean mothers' maternal sensitivity. We interviewed 92 German and 100 Korean mothers of first graders about their preference for proactive (anticipating children's needs) or reactive sensitivity (responding to children's direct cues) in different scenarios. Related parenting beliefs were assessed by asking the mothers to explain the reasons why they would prefer specific parenting behaviors. Results revealed significant cultural differences in reactive vs. proactive sensitivity preferences. Overall, German mothers were more likely to indicate that a mother should respond reactively and less likely to report that a mother should act proactively than were Korean mothers. Korean mothers gave preference to both reactive and proactive sensitivity depending on the scenario. With regard to parenting beliefs, analyses revealed that German and Korean mothers who preferred reactive sensitivity mainly explained their choices as attempts to encourage children's development of independence. In contrast, Korean and German mothers with a preference for proactive sensitivity were more likely to report that mothers would assist their children due to their immaturity in dealing with emotional distress. Results are discussed in the framework of the different meanings and functions of maternal sensitivity for socialization in different cultural contexts. PMID:23986740

German Television in the U.S. and Abroad

Science.gov (United States)

Ecke, Peter

2008-01-01

In this article, I review the options that teachers and students have to obtain German TV in the U.S.: through satellite and cable networks and by streaming, downloading, or recording TV programs through the internet. I also address how one can access TV programs over the air in the German-speaking countries by using a notebook PC and TV card.

German Television in the United States and Abroad

Science.gov (United States)

Ecke, Peter

2008-01-01

In this article, I review the options that teachers and students have to obtain German TV in the U.S.: through satellite and cable networks and by streaming, downloading, or recording TV programs through the internet. I also address how one can access TV programs over the air in the German-speaking countries by using a notebook PC and TV card.

A comparison of South African and German extrinsic and intrinsic motivation

Directory of Open Access Journals (Sweden)

Robin Snelgar

2017-04-01

Aim: The main objective of this study was to investigate similarities and differences concerning extrinsic and intrinsic motivation in the workplace between German and South African cultures by examining individuals with working experience and tertiary education specifically. In addition, the research investigated differences in the motivation of respondents with regard to demographics such as gender, age and income. Setting: The setting took place in South Africa and Germany. Methods: In the study, exploratory factor analysis was utilised to prove validity of Cinar, Bektas and Aslan’s two-dimensional measure of extrinsic and intrinsic motivation. Moreover, analysis of variance and t-tests were used to show differences among demographic variables. Descriptive statistics such as means, central tendency and Cronbach’s alpha were also utilised. Results: The results revealed preferences for intrinsic motivational factors for the whole sample with higher levels of intrinsic motivation for the South African respondents compared to German respondents. Demographic characteristics played a minor role in determining levels of intrinsic motivation within individuals. Culture, however, played the biggest role in determining one’s levels of intrinsic or extrinsic motivation. Conclusion: These findings play an important role in explaining differences in motivation between the two countries Germany and South Africa. It highlights the important role that cultural differences play in shaping one’s form of motivation.

German crowd-investing platforms: Literature review and survey

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David Grundy

2016-12-01

Full Text Available This article presents a comprehensive overview of the current German crowd-investing market drawing on a data-set of 31 crowd-investing platforms including the analysis of 265 completed projects. While crowd-investing market still only represents a niche in the German venture capital market, there is potential for an increase in both market volume and in average project investment. The market share is distributed among a few crowd-investing platforms with high entry barriers for new platforms although platforms that specialise in certain sectors have managed to successfully enter the market. German crowd-investing platforms are found to promote mainly internet-based enterprises (36% followed by projects in real estate (24% and green projects (19%, with the median money raised 100,000 euro.

Retrieval and the development of German federalism in the postwar period

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O. A. Mayor

2014-05-01

Full Text Available The path to understanding the nature of the German federal state is the analysis of its historical development. The process of establishing the federal structure of the German territory is long and quite complex , due to complex factors of social , legal and political nature. Federal relations on German soil in a given historical period is a reflection of political realities and lessons of the previous state . This paper considers the problem of revival of federal structures in the context of the new German state. Author determined arguments in favor of the federal structure of the state at the time. Established a task that had set the parents creators of the Weimar constitution. It is noted that much attention has been given implementation mechanisms controlling the balance of power and authority , not the vertical distribution of competencies. The features of the functioning of West German federalism. This paper analyzes the main structural problems and dysfunctions in the system of German federalism, which found its expression in the post­war period ; considered federal principles in Eastern Germany, who were in the tension field of centralist ideological trends in the postwar period. The author points out that the revival of German federalism influenced by factors such as domestic and foreign policy issues and concludes on the need for transformation of the federal system.

Globalization and the German model of capitalism--erosion or survival?

Science.gov (United States)

Lane, C

2000-06-01

The German business system has been regarded as a particularly tightly coupled system, with embeddedness of even multinational companies (MNCs) in their home base as particularly deep. A study of the impact of companies' changing internationalization, if not globalization, strategies is therefore especially suited to test competing claims about their effects on the German business system. Are we experiencing an erosion of this system, an adaptation in a largely path-dependent way, or even a greater specialization and stronger crystallization of the German business system? To investigate these questions, the paper examines a small number of German MNCs in their domestic and international context. More particularly, the work focuses on whether and how their emergent globalization activities affect the reproduction or erosion of the three institutional complexes which shape the factors of production: the financial system; the innovation system; and the industrial relations system. The paper concludes that a new type of transformation--hybridization--is emerging. It is regarded as a consequence of German companies' growing integration into a global economic system.

Importance of core/concrete interactions for German risk investigations and experimental verification

International Nuclear Information System (INIS)

Rohde, J.; Hicken, E.F.; Friederichs, H.G.; Schroedl, E.

1987-01-01

The relevance of Molten Core Concrete Interactions (MCCI) for risk oriented investigations of German LWR-plants is evaluated. The problems of MCCI have been intensely investigated since the mid seventies in connection with the German Risk Study, Phase A and B on PWR plants of German design. Many examinations of both theoretical and experimental nature have led to the development of computer codes like WECHSL. The basis for verification is the internationally well accepted BETA experiment. Code WECHSL and the knowledge gained from the BETA experiment have been applied for the final investigations in German Risk Study, Phase B. Knowledge gained will be illustrated and its importance MCCI for German LWR-concepts will be shown

German Cinema as a Vehicle for Teaching Culture, Literature and History.

Science.gov (United States)

Duncan, Annelise M.

The use of German film in four instructional contexts, based on experiences in developing a university course, is discussed. One use is as part of a German culture course taught in German, emphasizing the role of film as a cultural statement of its time, intended to be either a social criticism or a propaganda tool. A second use is integration of…

On Quality Intensification Expression Means in German And Lithuanian

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Ernesta Račienė

2013-12-01

Full Text Available The paper presents the analysis of German Adjectives’ derivational means, which intensify the meaning of quality, and which are compared with functional equivalents in Lithuanian. The intensification of quality is treated as the functional semantic category, implemented in various language levels. This semantics may be expressed morphologically, by lexical and syntactic means, as well as by stress and intonation. The German language has many first components of compound adjectives, representing the intensification of quality, such as: stock-, blitz-, hoch-, brand-, grund-, etc. The rendering function of this semantics is typical of German adjectives prefixes erz-, ur- as well as prefixes of foreign origin super-, ultra-, extra-, mega-, hyper-, top-. In the Lithuanian language, the intensifying meaning of quality is realized by syntactic com-pounds, while on the morphological level it can be conveyed by diminutive suffixes. The paper presents the comparison of German and Lithuanian quality intensification expression means in order to highlight typological similarities and differences.

The German version of the Camberwell Assessment of Need for the Elderly (CANE): evaluation of content validity and adaptation to the German-speaking context.

Science.gov (United States)

Stein, Janine; Luppa, Melanie; König, Hans-Helmut; Riedel-Heller, Steffi G

2015-11-01

The Camberwell Assessment of Need for the Elderly (CANE) was developed for the assessment of physical-, psychological-, and environment-related needs in the elderly. The aim of this study was to revise and adapt the German version of the CANE with regard to the content validity of the instrument. Following a multistage approach, face-to-face interviews using the CANE, an expert survey and a multidisciplinary consensus conference were conducted in order to evaluate the frequency and relevance of met and unmet needs in the German elderly population, and to modify the content of the CANE for the German-speaking countries. In Germany, unmet physical needs including physical health, medication, eyesight/hearing/communication, mobility/falls, self-care, and continence were found to have top priority closely followed by social needs (company, intimate relationships, daytime activities, information, and abuse/neglect). Psychological needs were the lowest ranked care category. Experts' proposals for the improvement of the German version of the CANE were collected. All findings were discussed and integrated in the multidisciplinary consensus conference with the result of a revised and adapted CANE that is applicable in the German-speaking context. The provision of an adapted and improved German version of the CANE may substantially contribute to a comprehensive and valid assessment of needs in the elderly population. The results of this study represent an important basis for comprehensive needs assessment in the elderly in the theoretical and practical field of healthcare and health services research.

Allergenic characterization of a novel allergen, homologous to chymotrypsin, from german cockroach.

Science.gov (United States)

Jeong, Kyoung Yong; Son, Mina; Lee, Jae Hyun; Hong, Chein Soo; Park, Jung Won

2015-05-01

Cockroach feces are known to be rich in IgE-reactive components. Various protease allergens were identified by proteomic analysis of German cockroach fecal extract in a previous study. In this study, we characterized a novel allergen, a chymotrypsin-like serine protease. A cDNA sequence homologous to chymotrypsin was obtained by analysis of German cockroach expressed sequence tag (EST) clones. The recombinant chymotrypsins from the German cockroach and house dust mite (Der f 6) were expressed in Escherichia coli using the pEXP5NT/TOPO vector system, and their allergenicity was investigated by ELISA. The deduced amino acid sequence of German cockroach chymotrypsin showed 32.7 to 43.1% identity with mite group 3 (trypsin) and group 6 (chymotrypsin) allergens. Sera from 8 of 28 German cockroach allergy subjects (28.6%) showed IgE binding to the recombinant protein. IgE binding to the recombinant cockroach chymotrypsin was inhibited by house dust mite chymotrypsin Der f 6, while it minimally inhibited the German cockroach whole body extract. A novel allergen homologous to chymotrypsin was identified from the German cockroach and was cross-reactive with Der f 6.

The Fifth German Oral Health Study (Fünfte Deutsche Mundgesundheitsstudie, DMS V) - rationale, design, and methods.

Science.gov (United States)

Jordan, Rainer A; Bodechtel, Constanze; Hertrampf, Katrin; Hoffmann, Thomas; Kocher, Thomas; Nitschke, Ina; Schiffner, Ulrich; Stark, Helmut; Zimmer, Stefan; Micheelis, Wolfgang

2014-12-29

Oral diseases rank among the most prevalent non-communicable diseases in modern societies. In Germany, oral epidemiological data show that both dental caries and periodontal diseases are highly prevalent, though significant improvements in oral health has been taking in the population within the last decades, particularly in children. It is, therefore, the aim of the Fifth German Oral Health Study (DMS V) to actualize the data on current oral health status and to gather information on oral health behavior and risk factors. In addition to current oral health monitoring, the study will also permit conclusions about trends in the development of oral health in Germany between 1989 and 2014. DMS V is a cross-sectional, multi-center, nationwide representative, socio-epidemiological study to investigate the oral health status und behavior of the German resident population in four age cohorts. Study participants are children (12-year-olds), adults (35- to 44-year-olds), young olds (65- to 74-year-olds), and old olds (75- to 100-year-olds) who are drawn from local residents' registration offices. Social-science investigation parameters concern subjective perceptions and attitudes regarding oral health and nutrition, sense of coherence, and socio-demographic data. Clinical oral parameters are tooth loss, caries and periodontitis, prosthodontic status, further developmental and acquired dental hard tissue and mucosal lesions. To ensure reproducibility, the dental investigators are trained and calibrated by experts and multiple reliability checks are performed throughout the field phase. Statistical analyses are calculated according to a detailed statistical analysis plan. The DMS studies first performed in 1989, 1992 and repeated in 1997 and 2005 are the only cross-sectional oral health studies conducted in Germany on a population-based national representative level. Updated prevalence and trend analyses of key oral diseases are, therefore, of major epidemiological and health

CD8+ T cell infiltration in breast and colon cancer: A histologic and statistical analysis.

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James Ziai

Full Text Available The prevalence of cytotoxic tumor infiltrating lymphocytes (TILs has demonstrated prognostic value in multiple tumor types. In particular, CD8 counts (in combination with CD3 and CD45RO have been shown to be superior to traditional UICC staging in colon cancer patients and higher total CD8 counts have been associated with better survival in breast cancer patients. However, immune infiltrate heterogeneity can lead to potentially significant misrepresentations of marker prevalence in routine histologic sections. We examined step sections of breast and colorectal cancer samples for CD8+ T cell prevalence by standard chromogenic immunohistochemistry to determine marker variability and inform practice of T cell biomarker assessment in formalin-fixed, paraffin-embedded (FFPE tissue samples. Stained sections were digitally imaged and CD8+ lymphocytes within defined regions of interest (ROI including the tumor and surrounding stroma were enumerated. Statistical analyses of CD8+ cell count variability using a linear model/ANOVA framework between patients as well as between levels within a patient sample were performed. Our results show that CD8+ T-cell distribution is highly homogeneous within a standard tissue sample in both colorectal and breast carcinomas. As such, cytotoxic T cell prevalence by immunohistochemistry on a single level or even from a subsample of biopsy fragments taken from that level can be considered representative of cytotoxic T cell infiltration for the entire tumor section within the block. These findings support the technical validity of biomarker strategies relying on CD8 immunohistochemistry.

[King's Parkinson's disease pain scale : Intercultural adaptation in the German language].

Science.gov (United States)

Jost, W H; Rizos, A; Odin, P; Löhle, M; Storch, A

2018-02-01

Pain is a frequent symptom of idiopathic Parkinson's disease and has a substantial impact on quality of life. The King's Parkinson's disease pain scale (KPPS) has become internationally established and is an English-language, standardized, reliable and valid scale for evaluation of pain in idiopathic Parkinson's disease. This article presents a validated version in German. The German translation was adapted interculturally and developed using an internationally recognized procedure in consultation with the authors of the original publication. The primary text was first translated by two bilingual neuroscientists independently of one another. Thereafter, the two versions were collated to generate a consensus version, which was accepted by the translators and preliminarily trialled with 10 patients. Hereafter, the German version was re-translated back into English by two other neurologists, again independently of one another, and a final consensus was agreed on using these versions. This English version was then compared with the original text by all of the translators, a process which entailed as many linguistic modifications to the German version as the translators considered necessary to generate a linguistically acceptable German version that was as similar as possible to the original English version. After this test text had been subsequently approved by the authors, the German text was applied to 50 patients in two hospitals, and reviewed as to its practicability and comprehensibility. This work led to the successful creation of an inter-culturally adapted and linguistically validated German version of the KPPS. The German version presented here is a useful scare for recording and quantifying pain in empirical studies, as well as in clinical practice.

German for Professional Purposes at the University of NSW.

Science.gov (United States)

Fischer, Gerhard

1992-01-01

A professionally oriented language course at the University of New South Wales (Australia) is described that is designed for students who have studied German in high school and wish to continue studying it to enhance their employment prospects. Both linguistic proficiency and German business culture are emphasized. (LB)

The German energy market: chronicle of a promised liberalization

International Nuclear Information System (INIS)

Heuraux, Ch.

2002-01-01

This book treats of: the German energy sector, its historical evolution since its creation during the second industrial revolution, the German energy market, the nuclear energy policy and its debate in the public opinion, and the present day trend towards the development of renewable energy sources. (J.S.)

[German medicine of the age of romanticism (1797-1848) as research problem].

Science.gov (United States)

Płonka-Syroka, B

1997-01-01

In the period between 1797 and 1848, German medicine was considerably influenced by philosophy. It absorbed ideas deriving from neo-Platonism and vitalism, as well as the modern philosophy of nature (Naturphilosophie), especially the ideas of Schelling. The article presents the main tendencies in the German medicine of that period: the distinct character of German medical thought as compared to the rest of Europe, the deductive character of medical theories, the grounding of medical thought in non-materialist philosophy and its close ties with the Protestant religion. The author's aim is investigate how German medicine of the period evolved away from European standards set by the model of medicine as an empirical science, based on the inductive method of research. The article presents the state of German medicine of the first half of the nineteenth century against the background of socio-cultural factors and relates German medical theory of the period to the social awareness of that time.

Enteric methane emissions from German dairy cows

DEFF Research Database (Denmark)

Dammgen, U; Rosemann, C; Haenel, H D

2012-01-01

Up to now, the German agricultural emission inventory used a model for the assessment of methane emissions from enteric fermentation that combined an estimate of the energy and feed requirements as a function of performance parameters and diet composition, with the constant methane conversion rate......, as stated by IPCC. A methane emission model was selected here that is based on German feed data. It was combined with the hitherto applied model describing energy requirements. The emission rates thus calculated deviate from those previously obtained. In the new model, the methane conversion rate is back......-calculated from emission rates and gross energy intake rates. For German conditions of animal performance and diet composition, the national means of methane conversion rates range between 71 kJ MJ(-1) and 61 kJ MJ(-1) for low and high performances (4700 kg animal(-1) a(-1) in 1990 to 7200 kg animal(-1) a(-1...

Interaction of oxygen vacancies in yttrium germanates

KAUST Repository

Wang, Hao

2012-01-01

Forming a good Ge/dielectric interface is important to improve the electron mobility of a Ge metal oxide semiconductor field-effect transistor. A thin yttrium germanate capping layer can improve the properties of the Ge/GeO 2 system. We employ electronic structure calculations to investigate the effect of oxygen vacancies in yttrium-doped GeO 2 and the yttrium germanates Y 2Ge 2O 7 and Y 2GeO 5. The calculated densities of states indicate that dangling bonds from oxygen vacancies introduce in-gap states, but the system remains insulating. However, yttrium-doped GeO 2 becomes metallic under oxygen deficiency. Y-doped GeO 2, Y 2Ge 2O 7 and Y 2GeO 5 are calculated to be oxygen substoichiometric under low Fermi energy conditions. The use of yttrium germanates is proposed as a way to effectively passivate the Ge/dielectric interface. This journal is © 2012 the Owner Societies.

D-1 report: The first German spacelab mission

Science.gov (United States)

1985-01-01

Introduction of a new popular magazine on the DI mission, the first West German Space mission. The DI project office publishes the magazine. The German sponsored astronauts are to study the gravitational effects of reduced gravity on the human generated processes of the environment. Other areas of concern are boundary surface and transport phenomena, physical chemisty and process engineering, metals and composite materials, and single crystals.

The new German radiation protection ordinance

International Nuclear Information System (INIS)

Pfeffer, W.; Weimer, G.

2003-01-01

According to European law, the Basic Safety Standards (BSS) published by the European Council in 1996 and the Council Directive on health protection of individuals against dangers of ionising radiation in relation to medical exposure had to be transferred into national law within due time. In 2001 the new Ordinance for the Implementation of the Euratom Guidelines on Radiation Protection] was published, which replaces the old Radiation Protection Ordinance. The new German Ordinance adapts the European Directive to German law, covering the general principles but even giving more details in many fields of radiation protection. The BSS scope certainly is much broader than the prescriptions important for the field of radiation protection in nuclear power plants. According to the scope of this workshop on occupational exposure in nuclear power plants - and as the BSS most probably will be quite familiar to all of you - after a short general overview on relevant contents of the German Ordinance, this presentation will focus on the main issues important in the operation of NPP and especially on some areas which may give rise to necessary changes caused by the new Ordinance. (A.L.B.)

The Strategic Challenge of Capacity for German Decommissioning

International Nuclear Information System (INIS)

Thomauske, Bruno; Moloney, Barry; Charlier, Frank

2016-01-01

Full text of publication follows: Experience of decommissioning across the world has allowed the nuclear industry to develop and enhance most of the technologies required for safe and efficient dismantling of Nuclear Power Plants (NPPs). One strategic challenge confronting the industry now is how to scale up implementation to address the burgeoning demand for dismantling of full size NPPs during the period 2016-2040. The German decommissioning programme will provide early evidence of whether the European industry can rise to this strategic challenge. It is widely reported in the media that German utilities will spend some Euro 30-40 Bn decommissioning NPPs during the next 25 years. In total, 22 NPPs will progress through the typical three stage programme encompassing post operations, dismantling and site clearance, with a peak occurring in the 2020's. Politically, immediate dismantling is strongly preferred as the strategy for the NPPs, so there will be a surge in decommissioning expenditure starting as soon as 2017. A critical issue is whether the German nuclear industry has sufficient capacity to deliver the programme, and where utilities may seek participation by other European companies. Innovation may be required, perhaps at a non-technical level. The circumstances of the German market require a thorough understanding. While the market is apparently open and receptive to international participation, three factors make it hard for foreign companies to penetrate. The political and regulatory environment is tough and for many foreign companies difficult to understand quickly. Utilities are mostly pursuing self-perform decommissioning strategies to preserve employment for their skilled workforce, limiting scope for some contractors. Finally, an innovative and highly experienced German nuclear industry can present formidable competition. Yet, this industry does not possess all the capacity needed for the utilities' programmes. Risks for new entrants can

19th Biannual Symposium of the German Aerospace Aerodynamics Association (STAB) and the German Society for Aeronautics and Astronautics (DGLR)

CERN Document Server

Heller, Gerd; Krämer, Ewald; Wagner, Claus; Breitsamter, Christian

2016-01-01

This book presents contributions to the 19th biannual symposium of the German Aerospace Aerodynamics Association (STAB) and the German Society for Aeronautics and Astronautics (DGLR). The individual chapters reflect ongoing research conducted by the STAB members in the field of numerical and experimental fluid mechanics and aerodynamics, mainly for (but not limited to) aerospace applications, and cover both nationally and EC-funded projects. Special emphasis is given to collaborative research projects conducted by German scientists and engineers from universities, research-establishments and industries. By addressing a number of cutting-edge applications, together with the relevant physical and mathematics fundamentals, the book provides readers with a comprehensive overview of the current research work in the field. Though the book’s primary emphasis is on the aerospace context, it also addresses further important applications, e.g. in ground transportation and energy. .

Darwin: German mystic or French rationalist?

Science.gov (United States)

Ghiselin, Michael T

2015-01-01

The notion that Charles Darwin embraced the German Romantic tradition seems plausible, given the early influence of Alexander von Humboldt. But this view fails to do justice to other scientific traditions. Darwin was a protégé of the Englishman John Stevens Henslow and was a follower of the Scott Charles Lyell. He had important debts to French scientists, notably Henri Milne-Edwards, Etienne and Isidore Geoffroy Saint-Hilaire, and Alphonse de Candolle. Many Germans were quite supportive of Darwin, but not all of these were encumbered by idealistic metaphysical baggage. Both Darwin and Anton Dohrn treated science as very much a cosmopolitan enterprise.

German family policy at the crossroads

DEFF Research Database (Denmark)

Wüst, Miriam

2009-01-01

Comparative studies of welfare reforms encounter two problems. First, the counterfactual problem is that in the real world schemes and their reforms do not coexist simultaneously and are hard to compare. Second, the contextual problem derives from the absence of comparable measures for change. Mi...... introduce a new concept of fairness and a focus on gender equality to German family policies........ Microsimulation helps to overcome these problems. It compares policy options - actual reforms or reform plans - simultaneously and provides a comparable measure: the disposable income of model families. This article uses a type-case approach to investigate recent reforms of the German parental leave benefit...

[The German guideline "legal evaluation after closed head injury"].

Science.gov (United States)

Wallesch, C W; Fries, W; Marx, P; du Mesnil de Rochemont, R; Roschmann, R; Schmidt, R; Schwerdtfeger, K; Tegenthoff, M; Widder, B

2013-09-01

In 2005, the "Deutsche Gesellschaft für Neurowissenschaftliche Begutachtung" (German Society for Neuroscientific Legal Evaluation) together with other Societies published a guideline for the legal evaluation of patients with closed head injuries. Meanwhile, not only scientific progress in imaging techniques but also in other fields such as neuropsychology has necessitated a revision, which is presented here. In the mean time, the handling of guidelines has been systematised in Germany so that a registration with the Cooperation of German Medical Learned Societies is applied for and publication in the German Guideline Registry is expected. © Georg Thieme Verlag KG Stuttgart · New York.

Recent mortality statistics for distally exposed A-bomb survivors: The lifetime cancer risk for exposure under 50 cGy (rad)

International Nuclear Information System (INIS)

Nussbaum, R.H.; Belsey, R.E.; Koehnlein, W.

1990-01-01

An analysis of mortality statistics from the most recent Life Span Study reports of Hiroshima and Nagasaki survivors (covering both the 1950-1982 and the 1950-1985 follow-up periods) indicates a significant difference (p < 0.001) in cancer mortality rates between two distally exposed groups of survivors with organ-absorbed radiation doses under 40 cSv. This implies a mean incremental lifetime cancer risk (exclusive of leukemias) of about 25 excess fatal cancers per 10,000 persons exposed to one additional cSv (rem) of ionizing radiation for persons who had been exposed to doses in the range 1-40 cSv above background levels. This risk value is independent of whether the original (T65DR) dosimetry assignments (choosing a value of 10 for the relative biological effectiveness of neutrons) or the new dosimetry estimates (DS86) are used. The present estimate of A-bomb survivor radiogenic cancer risk associated with low dose exposure was obtained directly from the observed cancer deaths in the low-dose exposure groups without reliance on model-dependent extrapolation from high-dose data. This low-dose risk estimate is about ten times larger than the risk estimates adopted previously by national and international radiation commissions as a basis for current radiation safety guidelines for workers and the general public. (author)

Germans or Jews? German-Speaking Jews in Post-War Europe: An Introduction

Czech Academy of Sciences Publication Activity Database

Čapková, Kateřina; Rechter, D.

2017-01-01

Roč. 62, November (2017), s. 69-74 ISSN 0075-8744 Institutional support: RVO:68378114 Keywords : Jews * Germans * post- war period Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings) https://academic.oup.com/leobaeck/issue/volume/62?browseBy=volume

Germans or Jews? German-Speaking Jews in Post-War Europe: An Introduction

Czech Academy of Sciences Publication Activity Database

Čapková, Kateřina; Rechter, D.

2017-01-01

Roč. 62, November (2017), s. 69-74 ISSN 0075-8744 Institutional support: RVO:68378114 Keywords : Jews * Germans * post-war period Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings) https://academic.oup.com/leobaeck/issue/volume/62?browseBy=volume

[Cases and duration of mechanical ventilation in German hospitals : An analysis of DRG incentives and developments in respiratory medicine].

Science.gov (United States)

Biermann, A; Geissler, A

2016-09-01

Diagnosis-related groups (DRGs) have been used to reimburse hospitals services in Germany since 2003/04. Like any other reimbursement system, DRGs offer specific incentives for hospitals that may lead to unintended consequences for patients. In the German context, specific procedures and their documentation are suspected to be primarily performed to increase hospital revenues. Mechanical ventilation of patients and particularly the duration of ventilation, which is an important variable for the DRG-classification, are often discussed to be among these procedures. The aim of this study was to examine incentives created by the German DRG-based payment system with regard to mechanical ventilation and to identify factors that explain the considerable increase of mechanically ventilated patients in recent years. Moreover, the assumption that hospitals perform mechanical ventilation in order to gain economic benefits was examined. In order to gain insights on the development of the number of mechanically ventilated patients, patient-level data provided by the German Federal Statistical Office and the German Institute for the Hospital Remuneration System were analyzed. The type of performed ventilation, the total number of ventilation hours, the age distribution, mortality and the DRG distribution for mechanical ventilation were calculated, using methods of descriptive and inferential statistics. Furthermore, changes in DRG-definitions and changes in respiratory medicine were compared for the years 2005-2012. Since the introduction of the DRG-based payment system in Germany, the hours of ventilation and the number of mechanically ventilated patients have substantially increased, while mortality has decreased. During the same period there has been a switch to less invasive ventilation methods. The age distribution has shifted to higher age-groups. A ventilation duration determined by DRG definitions could not be found. Due to advances in respiratory medicine, new

Storytelling and German Culture.

Science.gov (United States)

Cooper, Connie S. Eigenmann

The genre of fairytales, one structured form of storytelling, has been labeled "Marchen." German culture is orally transmitted in this generic form, and can be traced to a collection of 210 fairytales, the Grimm brothers'"Kinder-und Taus-Marchen," first published shortly after 1800. For this study, research questions were posed…

Statistical methods for quality assurance

International Nuclear Information System (INIS)

Rinne, H.; Mittag, H.J.

1989-01-01

This is the first German-language textbook on quality assurance and the fundamental statistical methods that is suitable for private study. The material for this book has been developed from a course of Hagen Open University and is characterized by a particularly careful didactical design which is achieved and supported by numerous illustrations and photographs, more than 100 exercises with complete problem solutions, many fully displayed calculation examples, surveys fostering a comprehensive approach, bibliography with comments. The textbook has an eye to practice and applications, and great care has been taken by the authors to avoid abstraction wherever appropriate, to explain the proper conditions of application of the testing methods described, and to give guidance for suitable interpretation of results. The testing methods explained also include latest developments and research results in order to foster their adoption in practice. (orig.) [de

Comparison of calculation methods for estimating annual carbon stock change in German forests under forest management in the German greenhouse gas inventory.

Science.gov (United States)

Röhling, Steffi; Dunger, Karsten; Kändler, Gerald; Klatt, Susann; Riedel, Thomas; Stümer, Wolfgang; Brötz, Johannes

2016-12-01

The German greenhouse gas inventory in the land use change sector strongly depends on national forest inventory data. As these data were collected periodically 1987, 2002, 2008 and 2012, the time series on emissions show several "jumps" due to biomass stock change, especially between 2001 and 2002 and between 2007 and 2008 while within the periods the emissions seem to be constant due to the application of periodical average emission factors. This does not reflect inter-annual variability in the time series, which would be assumed as the drivers for the carbon stock changes fluctuate between the years. Therefore additional data, which is available on annual basis, should be introduced into the calculations of the emissions inventories in order to get more plausible time series. This article explores the possibility of introducing an annual rather than periodical approach to calculating emission factors with the given data and thus smoothing the trajectory of time series for emissions from forest biomass. Two approaches are introduced to estimate annual changes derived from periodic data: the so-called logging factor method and the growth factor method. The logging factor method incorporates annual logging data to project annual values from periodic values. This is less complex to implement than the growth factor method, which additionally adds growth data into the calculations. Calculation of the input variables is based on sound statistical methodologies and periodically collected data that cannot be altered. Thus a discontinuous trajectory of the emissions over time remains, even after the adjustments. It is intended to adopt this approach in the German greenhouse gas reporting in order to meet the request for annually adjusted values.

Writings from the Margins: German-Jewish Women Poets from the Bukovina

Directory of Open Access Journals (Sweden)

Amy Colin

1997-01-01

Full Text Available Emerging at the crossroads of heterogeneous languages and cultures, German-Jewish women's poetry from the Bukovina displays the characteristics of its fascinating multilingual contextuality, yet it also bears the stigma of a double marginalization, for its representatives became time and again targets of both anti-Semitic attacks as well as gender discrimination. The present essay explores the untiring struggles of German-Jewish women authors from the Bokovina for acceptance within the Jewish and non-Jewish community. It analyzes their attempts to cope with social barriers, prejudices, and their difficult situation as both women and Jews. The essay also sets their poetry against the background of their multilingual contextuality. It is the Bukovinian biotope, where Ruthenians, Romanians, Germans, Jews, Armenians, Magyars, Poles, Lipovanes, and Hutsuls peacefully coexisted for many centuries, producing a variegated Romanian, Ruthenian, Austro-German, German-Jewish, and Yiddish literature as well as poets who were fluent in several languages.

From Idea to Implementation - Destination Finland : Developing a package holiday for German tourists

OpenAIRE

Preda, Tuija

2013-01-01

Topic of the present thesis is to develop customer-oriented tourism product proposals for German tourists travelling to Finland. In addition potential new upcoming segments are estimated. German tourism and German tourists are evaluated to figure out the segments of German tourists which are potentially interesting for Finnish tourism industry. The theory presents the customer oriented approach for product development in tourism industry. Moreover, customer orientation and customer orient...

Russian War Prisoners of the First World War in German Camps

OpenAIRE

Gulzhaukhar Kokebayeva; Erke Kartabayeva; Nurzipa Alpysbayeva

2014-01-01

The article considers the problem of the custody of Russian war prisoners in German camps. The German authorities treated Russian war prisoners in accordance with the ‘Provision of War Prisoners Custody’, approved by the Emperor on 11 August, 1914. The content of this document mainly corresponded to the Hague Convention Respecting the Laws and Customs of War on Land. But German authorities discriminated the war prisoners of different nationalities.

Lessons learnt from the MAGNET Malawian-German Hospital Partnership: the German perspective on contributions to patient care and capacity development.