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Sample records for genetic distance

  1. Inferring Pedigree Graphs from Genetic Distances

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    Tamura, Takeyuki; Ito, Hiro

    In this paper, we study a problem of inferring blood relationships which satisfy a given matrix of genetic distances between all pairs of n nodes. Blood relationships are represented by our proposed graph class, which is called a pedigree graph. A pedigree graph is a directed acyclic graph in which the maximum indegree is at most two. We show that the number of pedigree graphs which satisfy the condition of given genetic distances may be exponential, but they can be represented by one directed acyclic graph with n nodes. Moreover, an O(n3) time algorithm which solves the problem is also given. Although phylogenetic trees and phylogenetic networks are similar data structures to pedigree graphs, it seems that inferring methods for phylogenetic trees and networks cannot be applied to infer pedigree graphs since nodes of phylogenetic trees and networks represent species whereas nodes of pedigree graphs represent individuals. We also show an O(n2) time algorithm which detects a contradiction between a given pedigreee graph and distance matrix of genetic distances.

  2. Recovering geography from a matrix of genetic distances

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    Serva, M.; Vergni, D.; Volchenkov, D.; Vulpiani, A.

    2017-05-01

    Given a population of N elements with their geographical positions and the genetic (or lexical) distances between couples of elements (inferred, for example, from lexical differences between dialects which are spoken in different towns or from genetic differences between animal populations living in different faunal areas) a very interesting problem is to reconstruct the geographical positions of individuals using only genetic/lexical distances. From a technical point of view the program consists in extracting from the genetic/lexical distances a set of reconstructed geographical positions to be compared with the real ones. We show that geographical recovering is successful when the genetic/lexical distances are not a simple consequence of phylogenesis but also of horizontal transfers as, for example, vocabulary borrowings between different languages. Our results go well beyond the simple observation that geographical distances and genetic/lexical distances are correlated. The ascertainment of a correlation, in our perspective, merely is a prerequisite.

  3. Genetic distance sampling: a novel sampling method for obtaining core collections using genetic distances with an application to cultivated lettuce

    NARCIS (Netherlands)

    Jansen, J.; Hintum, van T.J.L.

    2007-01-01

    This paper introduces a novel sampling method for obtaining core collections, entitled genetic distance sampling. The method incorporates information about distances between individual accessions into a random sampling procedure. A basic feature of the method is that automatically larger samples are

  4. Measuring genetic distances between breeds: use of some distances in various short term evolution models

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    SanCristobal Magali

    2002-07-01

    Full Text Available Abstract Many works demonstrate the benefits of using highly polymorphic markers such as microsatellites in order to measure the genetic diversity between closely related breeds. But it is sometimes difficult to decide which genetic distance should be used. In this paper we review the behaviour of the main distances encountered in the literature in various divergence models. In the first part, we consider that breeds are populations in which the assumption of equilibrium between drift and mutation is verified. In this case some interesting distances can be expressed as a function of divergence time, t, and therefore can be used to construct phylogenies. Distances based on allele size distribution (such as (δμ2 and derived distances, taking a mutation model of microsatellites, the Stepwise Mutation Model, specifically into account, exhibit large variance and therefore should not be used to accurately infer phylogeny of closely related breeds. In the last section, we will consider that breeds are small populations and that the divergence times between them are too small to consider that the observed diversity is due to mutations: divergence is mainly due to genetic drift. Expectation and variance of distances were calculated as a function of the Wright-Malécot inbreeding coefficient, F. Computer simulations performed under this divergence model show that the Reynolds distance [57]is the best method for very closely related breeds.

  5. Topological Bias in Distance-Based Phylogenetic Methods: Problems with Over- and Underestimated Genetic Distances

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    Xuhua Xia

    2006-01-01

    Full Text Available I show several types of topological biases in distance-based methods that use the least-squares method to evaluate branch lengths and the minimum evolution (ME or the Fitch-Margoliash (FM criterion to choose the best tree. For a 6-species tree, there are two tree shapes, one with three cherries (a cherry is a pair of adjacent leaves descending from the most recent common ancestor, and the other with two. When genetic distances are underestimated, the 3-cherry tree shape is favored with either the ME or FM criterion. When the genetic distances are overestimated, the ME criterion favors the 2-cherry tree, but the direction of bias with the FM criterion depends on whether negative branches are allowed, i.e. allowing negative branches favors the 3-cherry tree shape but disallowing negative branches favors the 2-cherry tree shape. The extent of the bias is explored by computer simulation of sequence evolution.

  6. Genetic distance as an alternative to physical distance for definition of gene units in association studies.

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    Rodriguez-Fontenla, Cristina; Calaza, Manuel; Gonzalez, Antonio

    2014-05-28

    Some association studies, as the implemented in VEGAS, ALIGATOR, i-GSEA4GWAS, GSA-SNP and other software tools, use genes as the unit of analysis. These genes include the coding sequence plus flanking sequences. Polymorphisms in the flanking sequences are of interest because they involve cis-regulatory elements or they inform on untyped genetic variants trough linkage disequilibrium. Gene extensions have customarily been defined as ±50 Kb. This approach is not fully satisfactory because genetic relationships between neighbouring sequences are a function of genetic distances, which are only poorly replaced by physical distances. Standardized recombination rates (SRR) from the deCODE recombination map were used as units of genetic distances. We searched for a SRR producing flanking sequences near the ±50 Kb offset that has been common in previous studies. A SRR≥2 was selected because it led to gene extensions with median length=45.3 Kb and the simplicity of an integer value. As expected, boundaries of the genes defined with the ±50 Kb and with the SRR≥2 rules were rarely concordant. The impact of these differences was illustrated with the interpretation of top association signals from two large studies including many hits and their detailed analysis based in different criteria. The definition based in genetic distance was more concordant with the results of these studies than the based in physical distance. In the analysis of 18 top disease associated loci form the first study, the SRR≥2 genes led to a fully concordant interpretation in 17 loci; the ±50 Kb genes only in 6. Interpretation of the 43 putative functional genes of the second study based in the SRR≥2 definition only missed 4 of the genes, whereas the based in the ±50 Kb definition missed 10 genes. A gene definition based on genetic distance led to results more concordant with expert detailed analyses than the commonly used based in physical distance. The genome coordinates for each

  7. Estimation of genetic distance of rabbit by morphometric analysis

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    B Brahmantiyo

    2006-10-01

    Full Text Available The observation on morphological body conformation of English Spot (ES, Flemish Giant (FG, New Zealand White (NZWm, and Rex (Rexm from Magelang, Central Java, and New Zealand White (NZWb, Rex (Rexb, Satin (Satin and RS (RS from Balitnak-Ciawi, were carried out to determine estimation of Mahalanobis genetic distance. This research was held in Magelang (Central Java and Balitnak-Ciawi (West Java, 237 heads of Rabbits were used. Eleven different body parts were measured, those were head (length and width, ear (length and width, chest (girth, depth, and width, humerus length, radius-ulna length, tibia length and body length. General Linear Models were used in this observation (SAS package program. Simple discriminant analyses as further analyses were done for head (length and width, chest (girth, depth, and width, humerus length, radius-ulna length, tibia length and body length. ES, FG and NZWm rabbits had morphological size bigger than others. Mahalanobis genetic distance showed that NZWm and NZWb, Rexm and Rexb were had differences with genetic distances of 5.89139 and 6.75571 respectively. Rabbits from Magelang and from Balitnak were different on morphometric with mahalanobis distance of that region ranges were 4.89426 to 6.96749. Results from canonical analysis showed that the most discriminant variables were obtained by chest girth, chest width and humerus length on first canonical and head length on second cannonical.

  8. Genetic distance and species formation in evolving populations.

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    Higgs, P G; Derrida, B

    1992-11-01

    We compare the behavior of the genetic distance between individuals in evolving populations for three stochastic models. In the first model reproduction is asexual and the distribution of genetic distances reflects the genealogical tree of the population. This distribution fluctuates greatly in time, even for very large populations. In the second model reproduction is sexual with random mating allowed between any pair of individuals. In this case, the population becomes homogeneous and the genetic distance between pairs of individuals has small fluctuations which vanish in the limit of an infinitely large population. In the third model reproduction is still sexual but instead of random mating, mating only occurs between individuals which are genetically similar to each other. In that case, the population splits spontaneously into species which are in reproductive isolation from one another and one observes a steady state with a continual appearance and extinction of species in the population. We discuss this model in relation to the biological theory of speciation and isolating mechanisms. We also point out similarities between these three models of evolving populations and the theory of disordered systems in physics.

  9. Kin discrimination increases with genetic distance in a social amoeba.

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    Elizabeth A Ostrowski

    2008-11-01

    Full Text Available In the social amoeba Dictyostelium discoideum, thousands of cells aggregate upon starvation to form a multicellular fruiting body, and approximately 20% of them die to form a stalk that benefits the others. The aggregative nature of multicellular development makes the cells vulnerable to exploitation by cheaters, and the potential for cheating is indeed high. Cells might avoid being victimized if they can discriminate among individuals and avoid those that are genetically different. We tested how widely social amoebae cooperate by mixing isolates from different localities that cover most of their natural range. We show here that different isolates partially exclude one another during aggregation, and there is a positive relationship between the extent of this exclusion and the genetic distance between strains. Our findings demonstrate that D. discoideum cells co-aggregate more with genetically similar than dissimilar individuals, suggesting the existence of a mechanism that discerns the degree of genetic similarity between individuals in this social microorganism.

  10. Morphological profile and estimation of genetic distance of Simmental crossbred

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    Paskah Partogi Agung

    2014-06-01

    Full Text Available Research was done to study the profile of morphological characteristics of Simmental cross cattle in West Sumatera on several age categories and estimating the genetic distance compared to Simmental pure breed based on morphological parameters. Several morphological parameters of the 82 of Simmental cross cattle in West Sumatera and the 23 of Simmental pure breed has been measured. To analyze morphological data and the genetic distance a discriminant analysis was done. Based on statistical tests (t-test, body length, body height, hip height, hip width, chest circumference, chest width, chest depth, head length, and head height had significant difference (P<0.05 between 24-60 months Simmental pure breed and Simmental cross cattle bulls. Based on the similarity phenotypic analysis, it is known that all subpopulations of cattle in this research had a relatively high value (73.68-78.57%. Chest depth was the highest different morphometric factor (0.910. Morphological distribution map indicated that the Simmental cross cattle (subpopulations Agam and Lima Puluh Kota evenly distributed across all quadrants (I-IV while the Simmental pure breed (subpopulations BIB Lembang and BIBD Tuah Sakato distributed only in the I quadrants and II quadrants. The highest genetic distance was identified between cattle in Agam and BIBD Tuah Sakato while the lowest genetic distance was identified between cattle in Agam and Lima Puluh Kota. Based on phenogram tree structure, the observed Simmental cattle could be classified into 2 clusters, subpopulations of BIBD Tuah Sakato and BIB Lembang that represent Simmental pure breed configured their own cluster as well as a subpopulation of Agam and Lima Puluh Kota that represent Simmental cross cattle configured the others.

  11. Behaviour characteristics estimation tool of genetic distance between sheep breeds

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    Eko Handiwirawan

    2014-12-01

    Full Text Available Information on the estimation of genetic distances and differentiation among sheep breeds are needed in crossing and conservation programs. This research aims to study of utilizing behaviour characteristic variables to differentiate and estimate genetic distance between the sheep breeds. The study was conducted at Cilebut and Bogor Animal House of Indonesian Research Institute for Animal Production. Five sheep breeds used were Barbados Black Belly Cross (BC, Garut Composite (KG, Garut Local (LG, Sumatera Composite (KS and St. Croix Cross (SC, with total sample of 50 heads. A total of 10 variables of behavior traits were observed in this study. Analysis of variances and significance tests were applied to compare between sheep breeds and performed for all of behavior traits using PROC GLM of SAS Program ver. 9.0. PROC CANDISC was used for canonical discriminant analyses, the hierarchical clustering was performed using the PROC CLUSTER by Average Linkage method (Unweighted Pair-Group Method Using Arithmetic Averages, UPGMA, and the dendogram for the five sheep breeds was described using PROC TREE. The differentiator variables for the behavior traits were standing and feeding duration. The canonical plotting based on behavioral characteristics could differentiate BC, KS and LG (with KG and SC sheeps. Estimation of genetic distance based on the behavior traits is less accurate for grouping of sheep breeds.

  12. Using Genetic Distance to Infer the Accuracy of Genomic Prediction.

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    Marco Scutari

    2016-09-01

    Full Text Available The prediction of phenotypic traits using high-density genomic data has many applications such as the selection of plants and animals of commercial interest; and it is expected to play an increasing role in medical diagnostics. Statistical models used for this task are usually tested using cross-validation, which implicitly assumes that new individuals (whose phenotypes we would like to predict originate from the same population the genomic prediction model is trained on. In this paper we propose an approach based on clustering and resampling to investigate the effect of increasing genetic distance between training and target populations when predicting quantitative traits. This is important for plant and animal genetics, where genomic selection programs rely on the precision of predictions in future rounds of breeding. Therefore, estimating how quickly predictive accuracy decays is important in deciding which training population to use and how often the model has to be recalibrated. We find that the correlation between true and predicted values decays approximately linearly with respect to either FST or mean kinship between the training and the target populations. We illustrate this relationship using simulations and a collection of data sets from mice, wheat and human genetics.

  13. Enhancing the Internationalisation of Distance Education in the Biological Sciences: The DUNE Project and Genetic Engineering.

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    Leach, C. K.; And Others

    1997-01-01

    Describes the Distance Educational Network of Europe (DUNE) project that aims at enhancing the development of distance education in an international context. Highlights issues relating to the delivery of distance-learning courses in a transnational forum. Describes the genetic engineering course that aims at explaining the core techniques of…

  14. CDPOP: A spatially explicit cost distance population genetics program

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    Erin L. Landguth; S. A. Cushman

    2010-01-01

    Spatially explicit simulation of gene flow in complex landscapes is essential to explain observed population responses and provide a foundation for landscape genetics. To address this need, we wrote a spatially explicit, individual-based population genetics model (CDPOP). The model implements individual-based population modelling with Mendelian inheritance and k-allele...

  15. Effects of crossing distance and genetic relatedness on pollen performance in Alstroemeria aurea (Alstroemeriaceae).

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    Souto, Cintia P; Aizen, Marcelo A; Premoli, Andrea C

    2002-03-01

    Prezygotic barriers may represent effective mechanisms to avoid the deleterious effects of inbreeding. This study reports the existence of distance-dependent prezygotic barriers in self-compatible Alstroemeria aurea, a clonal herb native to temperate forests of the southern Andes. We analyzed pollen germination and tube growth as indicators of donor-recipient affinity using crossing distances of 1, 10, and 100 m. We used allozyme electrophoresis to determine the actual genetic relatedness between donor and recipient ramets. Pollen germination was not affected by distance between mates, but the number of pollen tubes reaching the base of the style increased strongly with distance between donor and recipient. This pattern was related to an increase in genetic dissimilarity with distance between mates. In contrast, pollen tube-style interactions did not change with distance when we restricted analysis to individuals at different distances that appeared to be genetically identical. This test implied genetic dissimilarity as the critical factor affecting pollen performance. We propose that the existence of prezygotic barriers might contribute to the high degree of genetic mixing exhibited by some clonal species.

  16. [A Study of the Relationship Among Genetic Distances, NIR Spectra Distances, and NIR-Based Identification Model Performance of the Seeds of Maize Iinbred Lines].

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    Liu, Xu; Jia, Shi-qiang; Wang, Chun-ying; Liu, Zhe; Gu, Jian-cheng; Zhai, Wei; Li, Shao-ming; Zhang, Xiao-dong; Zhu, De-hai; Huang, Hua-jun; An, Dong

    2015-09-01

    This paper explored the relationship among genetic distances, NIR spectra distances and NIR-based identification model performance of the seeds of maize inbred lines. Using 3 groups (total 15 pairs) of maize inbred lines whose genetic distaches are different as experimental materials, we calculates the genetic distance between these seeds with SSR markers and uses Euclidean distance between distributed center points of maize NIR spectrum in the PCA space as the distances of NIR spectrum. BPR method is used to build identification model of inbred lines and the identification accuracy is used as a measure of model identification performance. The results showed that, the correlation of genetic distance and spectra distancesis 0.9868, and it has a correlation of 0.9110 with the identification accuracy, which is highly correlated. This means near-Infrared spectrum of seedscan reflect genetic relationship of maize inbred lines. The smaller the genetic distance, the smaller the distance of spectrum, the poorer ability of model to identify. In practical application, near infrared spectrum analysis technology has the potential to be used to analyze maize inbred genetic relations, contributing much to genetic breeding, identification of species, purity sorting and so on. What's more, when creating a NIR-based identification model, the impact of the maize inbred lines which have closer genetic relationship should be fully considered.

  17. Molecular marker heterozygosities and genetic distances as correlates of production traits in F1 bovine crosses

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    Daniella Tambasco-Talhari

    2005-01-01

    Full Text Available Several studies have investigated the relationship between heterozygosity, genetic distance and production traits. The objective of the present study was to evaluate the influence of the degree of heterozygosity and genetic distance on growth, carcass and reproductive related features in F1 bovine crosses. We tested 10 polymorphic markers in 330 purebred cattle (Nelore, Canchim, Aberdeen Angus and Simental and 256 crossbred cattle belonging to four crossbred groups. Individual heterozygosities (Hi and multilocus genetic similarity (Dm were estimated and used in correlation analysis against individual phenotypic measurements. Significant (p < 0.05 Hi effects occurred for birth weight, 15 to 18 month weight, hot carcass weight and longissimus rib eye area. The extent to which increased heterozygosity (deltaH in F1 crosses can be predicted from the genetic distance of parental breeds was also investigated using Nei's standard genetic distance (Ds and standard heterozygosity (Hs. High correlations were found between deltaHi, deltaHs and the Ds of the parental breeds. Our results suggest that heterozygosity of the ten molecular markers used in this study may affect live weight during at least one growth phase. Parental genetic distance was a suitable predictor of the degree of progeny heterozygosity.

  18. Comparison of distance matrices in studies of population structure and genetic microdifferentiation: quadratic assignment.

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    Dow, M M; Cheverud, J M

    1985-11-01

    Questions concerning the relative effects of various evolutionary forces in molding the genetic variability exhibited by groups of human populations have typically been investigated by comparing a variety of genetic and cultural/historical "distance" matrices. A major methodological difficulty has been the lack of formal testing procedures with which to assess the degree of confirmation or disconfirmation of an estimated measure of relationship between such matrices. In this paper, we examine a very flexible matrix combinatorial procedure which generates statistical significance levels for correlational measures of pattern similarity between distance matrices. A recent generalization of the basic procedure to the three-matrix case allows questions concerning which of two matrices best fits a third matrix to be formally tested. Applications of these hypothesis testing and inference procedures to two separate sets of genetic, geographic, and cultural distance matrices illustrates their potential for finally solving a long-standing problem in anthropological genetics.

  19. Nonstationary patterns of isolation-by-distance: inferring measures of local genetic differentiation with Bayesian kriging.

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    Duforet-Frebourg, Nicolas; Blum, Michael G B

    2014-04-01

    Patterns of isolation-by-distance (IBD) arise when population differentiation increases with increasing geographic distances. Patterns of IBD are usually caused by local spatial dispersal, which explains why differences of allele frequencies between populations accumulate with distance. However, spatial variations of demographic parameters such as migration rate or population density can generate nonstationary patterns of IBD where the rate at which genetic differentiation accumulates varies across space. To characterize nonstationary patterns of IBD, we infer local genetic differentiation based on Bayesian kriging. Local genetic differentiation for a sampled population is defined as the average genetic differentiation between the sampled population and fictive neighboring populations. To avoid defining populations in advance, the method can also be applied at the scale of individuals making it relevant for landscape genetics. Inference of local genetic differentiation relies on a matrix of pairwise similarity or dissimilarity between populations or individuals such as matrices of FST between pairs of populations. Simulation studies show that maps of local genetic differentiation can reveal barriers to gene flow but also other patterns such as continuous variations of gene flow across habitat. The potential of the method is illustrated with two datasets: single nucleotide polymorphisms from human Swedish populations and dominant markers for alpine plant species.

  20. THE RELATIONSHIP BETWEEN HETEROSIS AND GENETIC DISTANCES BASED ON SSR MARKERS IN HELIANTHUS ANNUUS

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    A. V. Usatov

    2014-01-01

    Full Text Available Identifying the best inbred combinations for the development of commercial hybrid of sunflower remains the main challenge to sunflower breeders. In the present research the level of heterosis of F1 hybrids, genetic diversity of parental lines based on SSR markers, as well as its connection with specific combining ability of sunflower were studied. Ten sunflower elite inbred lines (3 restorer lines and 7 cytoplasmic male sterility lines and their hybrids were examined for plant height, seed yield, thousand seed mass, oil content and husk content. Field tests were carried out in 5-6 seasons. The level of heterosis was calculated using measurement of midparent heterosis. Genetic distance between pairs of tested sunflower inbred lines ranged from 0.45 to 0.74. Significant positive correlation was found between genetic distances among lines, measured using SSR markers and midparent heterosis for seed yield of hybrids (r = 0.79 p<0.05. The correlation between genetic distances and the level of midparent heterosis for other studied agronomic traits was not reliable. The dependence of seed yield of hybrids on genetic distances among parental lines may be used for planning of effective crossbreeding of sunflower. Further research is needed to determine the best inbred combinations for the development of commercial hybrid of sunflower.

  1. Migration distance rather than migration rate explains genetic diversity in human patrilocal groups.

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    Marks, Sarah J; Levy, Hila; Martinez-Cadenas, Conrado; Montinaro, Francesco; Capelli, Cristian

    2012-10-01

    In patrilocal groups, females preferentially move to join their mate's paternal relatives. The gender-biased gene flow generated by this cultural practice is expected to affect genetic diversity across human populations. Greater female than male migration is predicted to result in a larger decrease in between-group differentiation for mitochondrial DNA (mtDNA) than for the non-recombining part of the Y chromosome (NRY). We address the question of how patrilocality affects the distribution of genetic variation in human populations controlling for confounding factors such as ethno-linguistic heterogeneity and geographic distance which possibly explain the contradictory results observed in previous studies. By combining genetic and bio-demographic data from Lesotho and Spain, we show that preferential female migration over short distances appears to minimize the impact of a generally higher female migration rate in patrilocal communities, suggesting patrilocality might influence genetic variation only at short ranges.

  2. The distribution of pairwise genetic distances: a tool for investigating disease transmission.

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    Worby, Colin J; Chang, Hsiao-Han; Hanage, William P; Lipsitch, Marc

    2014-12-01

    Whole-genome sequencing of pathogens has recently been used to investigate disease outbreaks and is likely to play a growing role in real-time epidemiological studies. Methods to analyze high-resolution genomic data in this context are still lacking, and inferring transmission dynamics from such data typically requires many assumptions. While recent studies have proposed methods to infer who infected whom based on genetic distance between isolates from different individuals, the link between epidemiological relationship and genetic distance is still not well understood. In this study, we investigated the distribution of pairwise genetic distances between samples taken from infected hosts during an outbreak. We proposed an analytically tractable approximation to this distribution, which provides a framework to evaluate the likelihood of particular transmission routes. Our method accounts for the transmission of a genetically diverse inoculum, a possibility overlooked in most analyses. We demonstrated that our approximation can provide a robust estimation of the posterior probability of transmission routes in an outbreak and may be used to rule out transmission events at a particular probability threshold. We applied our method to data collected during an outbreak of methicillin-resistant Staphylococcus aureus, ruling out several potential transmission links. Our study sheds light on the accumulation of mutations in a pathogen during an epidemic and provides tools to investigate transmission dynamics, avoiding the intensive computation necessary in many existing methods.

  3. Genetic Distance and Genetic Identity between Hindu and Muslim populations of Barak Valley for ABO and Rh genes

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    Supriyo CHAKRABORTY

    2010-09-01

    Full Text Available A genetic study was carried out in two endogamous populations namely Hindus and Muslims in the Barak Valley Zone of Assam in India. Nei�s genetic distance and genetic identity between two populations were calculated on the basis of estimated allele frequencies of ABO and Rh blood group genes. The genetic distance between Hindus and Muslims was 0.12% for ABO gene and 0.10% for Rh gene. The genetic identity between two populations was estimated as 99.88% for ABO gene and 99.90% for Rh gene suggesting very high genetic similarity between these two populations. Observed heterozygosity estimate was higher in Hindus (0.5598 for ABO gene and 0.2822 for Rh gene than Muslims (0.5346 for ABO gene and 0.2408 for Rh gene indicating lesser inbreeding in Hindus than Muslims. Fixation index was lower in Hindus (16.02% for ABO gene and 43.56% for Rh gene than Muslims (19.80% for ABO gene and 51.84% for Rh gene. Panmictic index was higher in Hindus than Muslims for both the genes. Fixation and panmictic indices revealed that during evolutionary process the Hindus maintained more outbreeding feature than the Muslims in the valley. In this study, the concepts of genetic load of a population and genotype fitness were extended to alleles to estimate the magnitude of allele genetic load (GL and allele fitness for 3 alleles in ABO gene and for 2 alleles in Rh gene in two populations. The genetic load for O, A and B alleles were lower in Hindus than Muslims. Similar results for genetic load were found for the alleles of Rh gene in the comparison of two populations. The fitness estimates of O, A and B alleles for ABO gene and D and d alleles for Rh gene were higher in Hindus than Muslims. A population with low allele genetic load (GL and high allele fitness (AF might have greater survival advantage in nature in the absence of heterozygote advantage and higher adaptive value of the allele with increased frequency.

  4. Genetic distances between Chinese populations calculated on gene frequencies of 38 loci

    Institute of Scientific and Technical Information of China (English)

    杜若甫; 肖春杰; L. L. Cavalli-Sforza

    1997-01-01

    Genetic distances were calculated for Han subpopulations in different provinces, cities and au-tonomous regions and ethnic minorities in China by using gene frequency data of 38 loci, and genetic trees were con-structed. The results showed that, among both Han and ethnic minorities, there were two types, i.e. southern and northern Mongoloids, with Yangtze River as boundary. Therefore, both African origin theory and local origin theory about the modern man should answer the question; when did these two types separate and how did they develop. This paper also conclusively proved genetically that the Han subpopulations in different regions are genetically close to the lo-cal ethnic minorities, which indicates that much blood of ethnic minorities has mixed into Han, at the same time, some blood of Han also has mixed into the local ethnic minorities.

  5. Automatic multi-resolution image registration based on genetic algorithm and Hausdorff distance

    Institute of Scientific and Technical Information of China (English)

    Famao Ye; Lin Su; Shukai Li

    2006-01-01

    @@ Image registration is a crucial step in all image analysis tasks in which the final information is gained from the combination of various data sources, and it is difficult to automatically register due to the complexity of image. An approach based on genetic algorithm and Hausdorff distance to automatic image registration is presented. We use a multi-resolution edge tracker to find out the fine-quality edges and utilize the Hausdorff distance between the input image and the reference image as similarity measure. We use wavelet decomposition and genetic algorithm, which combine local search methods with global ones balancing exploration and exploitation, to speed up the search of the best transformation parameters.Experimental results show that the proposed approach is a promising method for registration of image.

  6. The interrelation between plus-hybrid effect on grain yield and genetic distance of studied hybrids

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    Božinović Sofija

    2010-01-01

    Full Text Available The combined effect of cytoplasmic male sterility and xenia is referred to as the Plus-Hybrid effect. A mixture of hybrids, in which one is a sterile female component and the other is a fertile pollinator, was sown. The objective of the present study was to determine whether the increase of a hybrid genetic distance would result in the increased gain from Plus-hybrid effects on grain yield. Two ZP hybrids (ZP 1 and ZP 2, i.e. their sterile and fertile counterparts, as well as, five hybrid pollinators (ZP 1, ZP 2, ZP 3, ZP 4 and ZP 5 were selected for the studies. The three-replicate trail was set up according to the randomized split-plot design at Zemun Polje in 2009. SSR markers were used to determine the genetic distance between hybrids. Ten out of total 12 applied primers gave results. Coefficients of similarity were estimated according to Dice and Jaccard. The greatest (0.37, i.e. smallest genetic distance (0.08, according to Dice, was obtained between hybrids ZP 1 and ZP 5, i.e. ZP 1 and ZP 4, respectively. Values of genetic distance according to Jaccard were between 0.14 (ZP 1 and ZP 4 and 0.54 (ZP 1 i ZP 5 . By using the cluster analysis, four hybrids (ZP 1, ZP 4, ZP 3 and ZP 2 were grouped into one sub-cluster that was loosely linked to ZP 5. The Plus-hybrid effect on grain yield of the hybrid ZP 1 was negative. The greatest gain was detected in the ZP 2st ' ZP 1 combination, between two hybrids that were genetically very similar and belonged to the same sub-cluster, and then in ZP 2st x ZP 3 and ZP 2st x ZP 4 combinations, between hybrids that also belonged to the same sub-cluster. It can be concluded that the Plus-hybrid effect, after all, depends not on the hybrid genetic distance but on the hybrid genotype.

  7. Habitat adaptation rather than genetic distance correlates with female preference in fire salamanders (Salamandra salamandra

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    Weitere Markus

    2009-06-01

    Full Text Available Abstract Background Although some mechanisms of habitat adaptation of conspecific populations have been recently elucidated, the evolution of female preference has rarely been addressed as a force driving habitat adaptation in natural settings. Habitat adaptation of fire salamanders (Salamandra salamandra, as found in Middle Europe (Germany, can be framed in an explicit phylogeographic framework that allows for the evolution of habitat adaptation between distinct populations to be traced. Typically, females of S. salamandra only deposit their larvae in small permanent streams. However, some populations of the western post-glacial recolonization lineage use small temporary ponds as larval habitats. Pond larvae display several habitat-specific adaptations that are absent in stream-adapted larvae. We conducted mate preference tests with females from three distinct German populations in order to determine the influence of habitat adaptation versus neutral genetic distance on female mate choice. Two populations that we tested belong to the western post-glacial recolonization group, but are adapted to either stream or pond habitats. The third population is adapted to streams but represents the eastern recolonization lineage. Results Despite large genetic distances with FST values around 0.5, the stream-adapted females preferred males from the same habitat type regardless of genetic distance. Conversely, pond-adapted females did not prefer males from their own population when compared to stream-adapted individuals of either lineage. Conclusion A comparative analysis of our data showed that habitat adaptation rather than neutral genetic distance correlates with female preference in these salamanders, and that habitat-dependent female preference of a specific pond-reproducing population may have been lost during adaptation to the novel environmental conditions of ponds.

  8. Sensitive dependencies and separation distances for genetically modified herbicide-tolerant crops.

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    Perry, Joe N

    2002-06-07

    The amount of land available for the coexistent growing of both organic and genetically modified herbicide-tolerant (GMHT) crops depends on the separation distance between the two types of crop. The form of the decline in the proportion of land available for growing one of these crop types due to increasing separation distance is linear on a suitable scale, but with a slope and intercept that are sensitively dependent on the proportion of the other crop already present. Spatially explicit simulations from realistic scenarios indicate that a major increase in separation distances, currently under review by the UK government, may have serious implications for the future coexistence of organic and GMHT crops in the UK.

  9. Population genetic structure and long-distance dispersal of a recently expanding migratory bird.

    Science.gov (United States)

    Ramos, Raül; Song, Gang; Navarro, Joan; Zhang, Ruiying; Symes, Craig T; Forero, Manuela G; Lei, Fumin

    2016-06-01

    Long-distance dispersal events and their derivable increases of genetic diversity have been highlighted as important ecological and evolutionary determinants that improve performances of range-expanding species. In the context of global environmental change, specific dispersal strategies have to be understood and foreseen if we like to prevent general biodiversity impoverishment or the spread of allochthonous diseases. We explored the genetic structure and potential population mixing on the recently range-expanding European bee-eater Merops apiaster. In addition, the species is suspected of harbouring and disseminating the most relevant disease for bees and apiculture, Nosema microsporidia. In agreement with complementary ringing recovery data and morphometric measurements, genetic results on two mitochondrial genes and 12 microsatellites showed a reasonably well-structured population partitioning along its breeding distribution. Microsatellite results indicated that not only did a few birds recently disperse long distance during their return migrations and change their natal breeding areas, but also that a group of allochthonous birds together founded a new colony. Although we did not provide evidence on the direct implication of birds in the widespread of Nosema parasites, our finding on the long-distance dispersal of bird flocks between remote breeding colonies adds concern about the role of European bee-eaters in the spread of such disease at a large, inter-continental scale.

  10. EPR Distance Measurements in Native Proteins with Genetically Encoded Spin Labels.

    Science.gov (United States)

    Schmidt, Moritz J; Fedoseev, Artem; Bücker, Dennis; Borbas, Julia; Peter, Christine; Drescher, Malte; Summerer, Daniel

    2015-12-18

    The genetic encoding of nitroxide amino acids in combination with electron paramagnetic resonance (EPR) distance measurements enables precise structural studies of native proteins, i.e. without the need for mutations to create unique reactive sites for chemical labeling and thus with minimal structural perturbation. We here report on in vitro DEER measurements in native E. coli thioredoxin (TRX) that establish the nitroxide amino acid SLK-1 as a spectroscopic probe that reports distances and conformational flexibilities in the enzyme with nonmutated catalytic centers that are not accessible by the use of the traditional methanethiosulfonate spin label (MTSSL). We generated a rotamer library for SLK-1 that in combination with molecular dynamics (MD) simulation enables predictions of distance distributions between two SLK-1 labels incorporated into a target protein. Toward a routine use of SLK-1 for EPR distance measurements in proteins and the advancement of the approach to intracellular environments, we study the stability of SLK-1 in E. coli cultures and lysates and establish guidelines for protein expression and purification that offer maximal nitroxide stability. These advancements and insights provide new perspectives for facile structural studies of native, endogenous proteins by EPR distance measurements.

  11. Genetic distances and phylogenetic trees of different Awassi sheep populations based on DNA sequencing.

    Science.gov (United States)

    Al-Atiyat, R M; Aljumaah, R S

    2014-01-01

    This study aimed to estimate evolutionary distances and to reconstruct phylogeny trees between different Awassi sheep populations. Thirty-two sheep individuals from three different geographical areas of Jordan and the Kingdom of Saudi Arabia (KSA) were randomly sampled. DNA was extracted from the tissue samples and sequenced using the T7 promoter universal primer. Different phylogenetic trees were reconstructed from 0.64-kb DNA sequences using the MEGA software with the best general time reverse distance model. Three methods of distance estimation were then used. The maximum composite likelihood test was considered for reconstructing maximum likelihood, neighbor-joining and UPGMA trees. The maximum likelihood tree indicated three major clusters separated by cytosine (C) and thymine (T). The greatest distance was shown between the South sheep and North sheep. On the other hand, the KSA sheep as an outgroup showed shorter evolutionary distance to the North sheep population than to the others. The neighbor-joining and UPGMA trees showed quite reliable clusters of evolutionary differentiation of Jordan sheep populations from the Saudi population. The overall results support geographical information and ecological types of the sheep populations studied. Summing up, the resulting phylogeny trees may contribute to the limited information about the genetic relatedness and phylogeny of Awassi sheep in nearby Arab countries.

  12. Linkage disequilibrium and the genetic distance in livestock populations: the impact of inbreeding

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    Baret Philippe V

    2004-05-01

    Full Text Available Abstract Genome-wide linkage disequilibrium (LD is subject to intensive investigation in human and livestock populations since it can potentially reveal aspects of a population history, permit to date them and help in fine-gene mapping. The most commonly used measure of LD between multiallelic loci is the coefficient D'. Data based on D' were recently published in humans, livestock and model animals. However, the properties of this coefficient are not well understood. Its sampling distribution and variance has received recent attention, but its expected behaviour with respect to genetic or physical distance remains unknown. Using stochastic simulations of populations having a finite size, we show that D' fits an exponential function having two parameters of simple biological interpretation: the residual value (rs towards which D' tends as the genetic distance increases and the distance R at which this value is reached. Properties of this model are evaluated as a function of the inbreeding coefficient (F. It was found that R and rs increase when F increases. The proposed model offers opportunities to better understand the patterns and the origins of LD in different populations and along different chromosomes.

  13. Population genetic structure and isolation by distance of Helicobacter pylori in Senegal and Madagascar.

    Science.gov (United States)

    Linz, Bodo; Vololonantenainab, Clairette Romaine Raharisolo; Seck, Abdoulaye; Carod, Jean-François; Dia, Daouda; Garin, Benoit; Ramanampamonjy, Rado Manitrala; Thiberge, Jean-Michel; Raymond, Josette; Breurec, Sebastien

    2014-01-01

    Helicobacter pylori has probably infected the human stomach since our origins and subsequently diversified in parallel with their human hosts. The genetic population history of H. pylori can therefore be used as a marker for human migration. We analysed seven housekeeping gene sequences of H. pylori strains isolated from 78 Senegalese and 24 Malagasy patients and compared them with the sequences of strains from other geographical locations. H. pylori from Senegal and Madagascar can be placed in the previously described HpAfrica1 genetic population, subpopulations hspWAfrica and hspSAfrica, respectively. These 2 subpopulations correspond to the distribution of Niger-Congo speakers in West and most of subequatorial Africa (due to Bantu migrations), respectively. H. pylori appears as a single population in Senegal, indicating a long common history between ethnicities as well as frequent local admixtures. The lack of differentiation between these isolates and an increasing genetic differentiation with geographical distance between sampling locations in Africa was evidence for genetic isolation by distance. The Austronesian expansion that started from Taiwan 5000 years ago dispersed one of the 10 subgroups of the Austronesian language family via insular Southeast Asia into the Pacific and Madagascar, and hspMaori is a marker for the entire Austronesian expansion. Strain competition and replacement of hspMaori by hpAfrica1 strains from Bantu migrants are the probable reasons for the presence of hspSAfrica strains in Malagasy of Southeast Asian descent. hpAfrica1 strains appear to be generalist strains that have the necessary genetic diversity to efficiently colonise a wide host spectrum.

  14. Optimal combined overcurrent and distance relays co-ordination using a new genetic algorithm method

    Energy Technology Data Exchange (ETDEWEB)

    Kamangar, S.S.H.; Abyaneh, H.A.; Chabanloo, R.M. [Amirkabir Univ. of Technology, Tehran (Iran, Islamic Republic of). Dept. of Electrical Engineering; Razavi, F. [Tafresh Univ. (Iran, Islamic Republic of). Dept. of Electrical Engineering

    2010-04-15

    This paper introduced a new method to optimize the coordination of overcurrent (OC) relays using genetic algorithm (GA). GA is an intelligent optimization technique that can adjust the setting of relays without being based on an initial guess or trapped in the local minimum values, which is the disadvantage of linear programming techniques, such as simplex, 2-phase simplex, and dual simplex techniques. The objective function (OF) of GA is modified by adding a new term to OF to fulfill the coordination of both OC and distance relays. Two power network systems were analyzed using the new computer program, and the results that were obtained show that the method is both efficient and accurate. Transmission and subtransmission protection systems commonly use OC and distance relays. 12 refs., 6 tabs., 5 figs.

  15. A nearest neighbour approach by genetic distance to the assignment of individual trees to geographic origin.

    Science.gov (United States)

    Degen, Bernd; Blanc-Jolivet, Céline; Stierand, Katrin; Gillet, Elizabeth

    2017-03-01

    During the past decade, the use of DNA for forensic applications has been extensively implemented for plant and animal species, as well as in humans. Tracing back the geographical origin of an individual usually requires genetic assignment analysis. These approaches are based on reference samples that are grouped into populations or other aggregates and intend to identify the most likely group of origin. Often this grouping does not have a biological but rather a historical or political justification, such as "country of origin". In this paper, we present a new nearest neighbour approach to individual assignment or classification within a given but potentially imperfect grouping of reference samples. This method, which is based on the genetic distance between individuals, functions better in many cases than commonly used methods. We demonstrate the operation of our assignment method using two data sets. One set is simulated for a large number of trees distributed in a 120km by 120km landscape with individual genotypes at 150 SNPs, and the other set comprises experimental data of 1221 individuals of the African tropical tree species Entandrophragma cylindricum (Sapelli) genotyped at 61 SNPs. Judging by the level of correct self-assignment, our approach outperformed the commonly used frequency and Bayesian approaches by 15% for the simulated data set and by 5-7% for the Sapelli data set. Our new approach is less sensitive to overlapping sources of genetic differentiation, such as genetic differences among closely-related species, phylogeographic lineages and isolation by distance, and thus operates better even for suboptimal grouping of individuals. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  16. Multivariate analysis to determine the genetic distance among backcross papaya (Carica papaya) progenies.

    Science.gov (United States)

    Ramos, H C C; Pereira, M G; Gonçalves, L S A; Berilli, A P C G; Pinto, F O; Ribeiro, E H

    2012-05-14

    Morpho-agronomic and molecular (RAPD and ISSR markers) data were used to evaluate genetic distances between papaya backcross progenies in order to help identify agronomically superior genotypes. Thirty-two papaya progenies were evaluated based on 15 morpho-agronomic characteristics, 20 ISSR and 19 RAPD primers. Manhattan, Jaccard and Gower distances were used to estimate differences based on continuous and binary data and combined analyses, respectively. Except for production, there were significant differences in the continuous variables among the genotypes. The molecular analysis revealed 193 dominant markers (ISSR and RAPD), being 53 polymorphic loci. Among the various clusters that were generated, the one based on a combined analysis of morpho-agronomic and molecular data gave the highest cophenetic correlation (0.72) compared to individual analysis, consistently allocating the progenies into six groups. We found that the Gower algorithm was more coherent in the discrimination of the genotypes, demonstrating that a combination of molecular and agronomic data is valuable for studies of genetic dissimilarity in papaya.

  17. Correlation among genetic, Euclidean, temporal, and herd ownership distances of porcine reproductive and respiratory syndrome virus strains in Quebec, Canada

    Directory of Open Access Journals (Sweden)

    Lambert Marie-Ève

    2012-06-01

    Full Text Available Abstract Background Porcine reproductive and respiratory syndrome (PRRS is a viral disease that has a major economic impact for the swine industry. Its control is mostly directed towards preventing its spread which requires a better understanding of the mechanisms of transmission of the virus between herds. The objectives of this study were to describe the genetic diversity and to assess the correlation among genetic, Euclidean and temporal distances and ownership to better understand pathways of transmission. Results A cross-sectional study was conducted on sites located in a high density area of swine production in Quebec. Geographical coordinates (longitude/latitude, date of submission and ownership were obtained for each site. ORF5 sequencing was attempted on PRRSV positive sites. Proportion of pairwise combinations of strains having ≥98% genetic homology were analysed according to Euclidean distances and ownership. Correlations between genetic, Euclidean and temporal distances and ownership were assessed using Mantel tests on continuous and binary matrices. Sensitivity of the correlations between genetic and Euclidean as well as temporal distances was evaluated for different Euclidean and temporal distance thresholds. An ORF5 sequence was identified for 132 of the 176 (75% PRRSV positive sites; 122 were wild-type strains. The mean (min-max genetic, Euclidean and temporal pairwise distances were 11.6% (0–18.7, 15.0 km (0.04-45.7 and 218 days (0–852, respectively. Significant positive correlations were observed between genetic and ownership, genetic and Euclidean and between genetic and temporal binary distances. The relationship between genetic and ownership suggests either common sources of animals or semen, employees, technical services or vehicles, whereas that between genetic and Euclidean binary distances is compatible with area spread of the virus. The latter correlation was observed only up to 5 km. Conclusions This study

  18. Trans-National Genetic Distance and Genetic Identity of Barak Valley Hindus en Route the Journey of Mankind from Africa for ABO Gene

    Directory of Open Access Journals (Sweden)

    Supriyo CHAKRABORTY

    2011-08-01

    Full Text Available The present study aimed at estimating the genetic distance and genetic identity between Barak Valley Hindus and other twenty four nations for ABO blood group gene along the route of historic journey of mankind from Africa as proposed by Stephen Oppenheimer to gain insights on the evolutionary relationship and genetic closeness of the Hindus with other nations. Barak Valley Zone, located in southern part of Assam state in North East India, has inhabited the major endogamous group, the Hindus, for several centuries. Over the last few decades, they have maintained distinct culture and life style. This study used ABO gene frequency data of these populations to estimate Neis standard genetic distance and genetic identity of population genetics between Barak Valley Hindus and other nations. The historic journey of mankind commenced from Africa about 200,000 years ago (www.bradshawfoundation.com. Genetic distance estimate ranged from 0.07 to 5.18%. Barak Valley Hindus (BVH showed relatively low genetic distance for ABO gene with the populations of Saudi Arabia (0.07%, India (0.13%, Borneo (0.40%, Russia (0.59%, Central Asia (0.60%, Siberia (0.60%, South China (0.71% and Sri Lanka (0.93% suggesting high genetic identity and possible evolutionary relationship of BVH during migration with these nations. But the BVH showed highest genetic distance with Australia (5.18% followed by Norway (4.13%, Sudan (3.89% and Sweden (3.60% indicating low genetic identity of BVH with these nations. Migration was not the key determining factor in changing the ABO gene frequency in human populations.

  19. Decomposed pairwise regression analysis of genetic and geographic distances reveals a metapopulation structure of stream-dwelling Dolly Varden charr.

    Science.gov (United States)

    Koizumi, Itsuro; Yamamoto, Shoichiro; Maekawa, Koji

    2006-10-01

    Isolation by distance is usually tested by the correlation of genetic and geographic distances separating all pairwise populations' combinations. However, this method can be significantly biased by only a few highly diverged populations and lose the information of individual population. To detect outlier populations and investigate the relative strengths of gene flow and genetic drift for each population, we propose a decomposed pairwise regression analysis. This analysis was applied to the well-described one-dimensional stepping-stone system of stream-dwelling Dolly Varden charr (Salvelinus malma). When genetic and geographic distances were plotted for all pairs of 17 tributary populations, the correlation was significant but weak (r(2) = 0.184). Seven outlier populations were determined based on the systematic bias of the regression residuals, followed by Akaike's information criteria. The best model, 10 populations included, showed a strong pattern of isolation by distance (r(2) = 0.758), suggesting equilibrium between gene flow and genetic drift in these populations. Each outlier population was also analysed by plotting pairwise genetic and geographic distances against the 10 nonoutlier populations, and categorized into one of the three patterns: strong genetic drift, genetic drift with a limited gene flow and a high level of gene flow. These classifications were generally consistent with a priori predictions for each population (physical barrier, population size, anthropogenic impacts). Combined the genetic analysis with field observations, Dolly Varden in this river appeared to form a mainland-island or source-sink metapopulation structure. The generality of the method will merit many types of spatial genetic analyses.

  20. Does genetic distance between parental species influence outcomes of hybridization among coral reef butterflyfishes?

    Science.gov (United States)

    Montanari, Stefano R; Hobbs, Jean-Paul A; Pratchett, Morgan S; Bay, Line K; Van Herwerden, Lynne

    2014-06-01

    Christmas Island is located at the overlap of the Indian and Pacific Ocean marine provinces and is a hot spot for marine hybridization. Here, we evaluate the ecological framework and genetic consequences of hybridization between butterflyfishes Chaetodon guttatissimus and Chaetodon punctatofasciatus. Further, we compare our current findings to those from a previous study of hybridization between Chaetodon trifasciatus and Chaetodon lunulatus. For both species groups, habitat and dietary overlap between parental species facilitate frequent heterospecific encounters. Low abundance of potential mates promotes heterospecific pair formation and the breakdown of assortative mating. Despite similarities in ecological frameworks, the population genetic signatures of hybridization differ between the species groups. Mitochondrial and nuclear data from C. guttatissimus × C. punctatofasciatus (1% divergence at cyt b) show bidirectional maternal contributions and relatively high levels of introgression, both inside and outside the Christmas Island hybrid zone. In contrast, C. trifasciatus × C. lunulatus (5% cyt b divergence) exhibit unidirectional mitochondrial inheritance and almost no introgression. Back-crossing of hybrid C. guttatissimus × C. punctatofasciatus and parental genotypes may eventually confound species-specific signals within the hybrid zone. In contrast, hybrids of C. trifasciatus and C. lunulatus may coexist with and remain genetically distinct from the parents. Our results, and comparisons with hybridization studies in other reef fish families, indicate that genetic distance between hybridizing species may be a factor influencing outcomes of hybridization in reef fish, which is consistent with predictions from terrestrially derived hybridization theory. © 2014 John Wiley & Sons Ltd.

  1. Diagnostic Genetics at a Distance: Von Hippel-Lindau Disease and a Novel Mutation

    Directory of Open Access Journals (Sweden)

    Clare Brookes

    2013-01-01

    Full Text Available Genetic testing at a distance is commonplace where members of a family with a segregating germline mutation are geographically separated. For the most part, this challenge is addressed through the intervention of health professionals in taking and/or processing blood samples for subsequent couriering of DNA to a referral laboratory. In some circumstances, however, the collecting of pivotal clinical material may involve direct patient involvement. We describe such a situation where noninvasive saliva samples were provided by members of a family manifesting Von Hippel-Lindau (VHL disease. The analysis identified a novel mutation in the VHL gene that was used to exclude other family members as being at risk of VHL disease.

  2. The Real maccoyii: Identifying Tuna Sushi with DNA Barcodes – Contrasting Characteristic Attributes and Genetic Distances

    Science.gov (United States)

    Lowenstein, Jacob H.; Amato, George; Kolokotronis, Sergios-Orestis

    2009-01-01

    Background The use of DNA barcodes for the identification of described species is one of the least controversial and most promising applications of barcoding. There is no consensus, however, as to what constitutes an appropriate identification standard and most barcoding efforts simply attempt to pair a query sequence with reference sequences and deem identification successful if it falls within the bounds of some pre-established cutoffs using genetic distance. Since the Renaissance, however, most biological classification schemes have relied on the use of diagnostic characters to identify and place species. Methodology/Principal Findings Here we developed a cytochrome c oxidase subunit I character-based key for the identification of all tuna species of the genus Thunnus, and compared its performance with distance-based measures for identification of 68 samples of tuna sushi purchased from 31 restaurants in Manhattan (New York City) and Denver, Colorado. Both the character-based key and GenBank BLAST successfully identified 100% of the tuna samples, while the Barcode of Life Database (BOLD) as well as genetic distance thresholds, and neighbor-joining phylogenetic tree building performed poorly in terms of species identification. A piece of tuna sushi has the potential to be an endangered species, a fraud, or a health hazard. All three of these cases were uncovered in this study. Nineteen restaurant establishments were unable to clarify or misrepresented what species they sold. Five out of nine samples sold as a variant of “white tuna” were not albacore (T. alalunga), but escolar (Lepidocybium flavorunneum), a gempylid species banned for sale in Italy and Japan due to health concerns. Nineteen samples were northern bluefin tuna (T. thynnus) or the critically endangered southern bluefin tuna (T. maccoyii), though nine restaurants that sold these species did not state these species on their menus. Conclusions/Significance The Convention on International Trade

  3. The real maccoyii: identifying tuna sushi with DNA barcodes--contrasting characteristic attributes and genetic distances.

    Directory of Open Access Journals (Sweden)

    Jacob H Lowenstein

    Full Text Available BACKGROUND: The use of DNA barcodes for the identification of described species is one of the least controversial and most promising applications of barcoding. There is no consensus, however, as to what constitutes an appropriate identification standard and most barcoding efforts simply attempt to pair a query sequence with reference sequences and deem identification successful if it falls within the bounds of some pre-established cutoffs using genetic distance. Since the Renaissance, however, most biological classification schemes have relied on the use of diagnostic characters to identify and place species. METHODOLOGY/PRINCIPAL FINDINGS: Here we developed a cytochrome c oxidase subunit I character-based key for the identification of all tuna species of the genus Thunnus, and compared its performance with distance-based measures for identification of 68 samples of tuna sushi purchased from 31 restaurants in Manhattan (New York City and Denver, Colorado. Both the character-based key and GenBank BLAST successfully identified 100% of the tuna samples, while the Barcode of Life Database (BOLD as well as genetic distance thresholds, and neighbor-joining phylogenetic tree building performed poorly in terms of species identification. A piece of tuna sushi has the potential to be an endangered species, a fraud, or a health hazard. All three of these cases were uncovered in this study. Nineteen restaurant establishments were unable to clarify or misrepresented what species they sold. Five out of nine samples sold as a variant of "white tuna" were not albacore (T. alalunga, but escolar (Lepidocybium flavorunneum, a gempylid species banned for sale in Italy and Japan due to health concerns. Nineteen samples were northern bluefin tuna (T. thynnus or the critically endangered southern bluefin tuna (T. maccoyii, though nine restaurants that sold these species did not state these species on their menus. CONCLUSIONS/SIGNIFICANCE: The Convention on

  4. Genetics of recent habitat contraction and reduction in population size: does isolation by distance matter?

    Science.gov (United States)

    Leblois, Raphael; Estoup, Arnaud; Streiff, Rejane

    2006-10-01

    Fragmentation and loss of natural habitats are recognized as major threats to contemporary flora and fauna. Detecting past or current reductions in population size is therefore a major aim in conservation genetics. Statistical methods developed to this purpose have tended to ignore the effects of spatial population structure. However in many species, individual dispersal is restricted in space and fine-scale spatial structure such as isolation by distance (IBD) is commonly observed in continuous populations. Using a simulation-based approach, we investigated how comparative and single-point methods, traditionally used in a Wright-Fisher (WF) population context for detecting population size reduction, behave for IBD populations. We found that a complex 'quartet' of factors was acting that includes restricted dispersal, population size (i.e. habitat size), demographic history, and sampling scale. After habitat reduction, IBD populations were characterized by a stronger inertia in the loss of genetic diversity than WF populations. This inertia increases with the strength of IBD, and decreases when the sampling scale increases. Depending on the method used to detect a population size reduction, a local sampling can be more informative than a sample scaled to habitat size or vice versa. However, IBD structure led in numerous cases to incorrect inferences on population demographic history. The reanalysis of a real microsatellite data set of skink populations from fragmented and intact rainforest habitats confirmed most of our simulation results.

  5. Phenotypic evolution by distance in fluctuating environments: The contribution of dispersal, selection and random genetic drift.

    Science.gov (United States)

    Engen, Steinar; Sæther, Bernt-Erik

    2016-06-01

    Here we analyze how dispersal, genetic drift, and adaptation to the local environment affect the geographical differentiation of a quantitative character through natural selection using a spatial dynamic model for the evolution of the distribution of mean breeding values in space and time. The variation in optimal phenotype is described by local Ornstein-Uhlenbeck processes with a given spatial autocorrelation. Selection and drift are assumed to be governed by phenotypic variation within areas with a given mean breeding value and constant additive genetic variance. Between such neighboring areas there will be white noise variation in mean breeding values, while the variation at larger distances has a spatial structure and a spatial scale that we investigate. The model is analyzed by solving balance equations for the stationary distribution of mean breeding values. We also present scaling results for the spatial autocovariance function for mean breeding values as well as that for the covariance between mean breeding value and the optimal phenotype expressing local adaption. Our results show in particular how these spatial scales depend on population density. For large densities the spatial scale of fluctuations in mean breeding values have similarities with corresponding results in population dynamics, where the effect of migration on spatial scales may be large if the local strength of density regulation is small. In our evolutionary model strength of density regulation corresponds to strength of local selection so that weak local selection may produce large spatial scales of autocovariances. Genetic drift and stochastic migration are shown to act through the population size within a characteristic area with much smaller variation in optimal phenotypes than in the whole population.

  6. Social Structure and Genetic Distance Mediate Nestmate Recognition and Aggressiveness in the Facultative Polygynous Ant Pheidole pallidula.

    Science.gov (United States)

    Fournier, Denis; de Biseau, Jean-Christophe; De Laet, Sophie; Lenoir, Alain; Passera, Luc; Aron, Serge

    2016-01-01

    In social insects, the evolutionary stability of cooperation depends on the privileged relationships between individuals of the social group, which is facilitated by the recognition of relatives. Nestmate recognition is based on genetically determined cues and/or environmentally derived chemical components present on the cuticle of individuals. Here, we studied nestmate recognition in the ant Pheidole pallidula, a species where both single-queen (monogyne) and multiple-queen (polygyne) colonies co-occur in the same population. We combined geographical, genetic and chemical analyses to disentangle the factors influencing the level of intraspecific aggressiveness. We show that encounters between workers from neighbouring colonies (i.e., nests less than 5 m away) are on average less aggressive than those between workers from more distant colonies. Aggressive behaviour is associated with the level of genetic difference: workers from monogyne colonies are more aggressive than workers from polygyne colonies, and the intensity of aggressiveness is positively associated with the genetic distance between colonies. Since the genetic distance is correlated with the spatial distance between pairs of colonies, the lower level of aggression toward neighbours may result from their higher relatedness. In contrast, the analysis of overall cuticular hydrocarbon profiles shows that aggressive behaviour is associated neither with the chemical diversity of colonies, nor with the chemical distances between them. When considering methyl-branched alkanes only, however, chemical distances differed between monogyne and polygyne colonies and were significantly associated with aggressiveness. Altogether, these results show that the social structure of colonies and the genetic distances between colonies are two major factors influencing the intensity of agonistic behaviours in the ant P. pallidula.

  7. Using Genealogical Mapping and Genetic Neighborhood Sizes to Quantify Dispersal Distances in the Neotropical Passerine, the Black-Capped Vireo.

    Science.gov (United States)

    Athrey, Giridhar; Lance, Richard F; Leberg, Paul L

    2015-01-01

    Dispersal is a key demographic process, ultimately responsible for genetic connectivity among populations. Despite its importance, quantifying dispersal within and between populations has proven difficult for many taxa. Even in passerines, which are among the most intensely studied, individual movement and its relation to gene flow remains poorly understood. In this study we used two parallel genetic approaches to quantify natal dispersal distances in a Neotropical migratory passerine, the black-capped vireo. First, we employed a strategy of sampling evenly across the landscape coupled with parentage assignment to map the genealogical relationships of individuals across the landscape, and estimate dispersal distances; next, we calculated Wright's neighborhood size to estimate gene dispersal distances. We found that a high percentage of captured individuals were assigned at short distances within the natal population, and males were assigned to the natal population more often than females, confirming sex-biased dispersal. Parentage-based dispersal estimates averaged 2400m, whereas gene dispersal estimates indicated dispersal distances ranging from 1600-4200 m. Our study was successful in quantifying natal dispersal distances, linking individual movement to gene dispersal distances, while also providing a detailed look into the dispersal biology of Neotropical passerines. The high-resolution information was obtained with much reduced effort (sampling only 20% of breeding population) compared to mark-resight approaches, demonstrating the potential applicability of parentage-based approaches for quantifying dispersal in other vagile passerine species.

  8. Parallelization and optimization of genetic analyses in isolation by distance web service

    Directory of Open Access Journals (Sweden)

    Otto James S

    2009-06-01

    Full Text Available Abstract Background The Isolation by Distance Web Service (IBDWS is a user-friendly web interface for analyzing patterns of isolation by distance in population genetic data. IBDWS enables researchers to perform a variety of statistical tests such as Mantel tests and reduced major axis regression (RMA, and returns vector based graphs. The more than 60 citations since 2005 confirm the popularity and utility of this website. Despite its usefulness, the data sets with over 65 populations can take hours or days to complete due to the computational intensity of the statistical tests. This is especially troublesome for web-based software analysis, since users tend to expect real-time results on the order of seconds, or at most, minutes. Moreover, as genetic data continue to increase and diversify, so does the demand for more processing power. In order to increase the speed and efficiency of IBDWS, we first determined which aspects of the code were most time consuming and whether they might be amenable to improvements by parallelization or algorithmic optimization. Results Runtime tests uncovered two areas of IBDWS that consumed significant amounts of time: randomizations within the Mantel test and the RMA calculations. We found that these sections of code could be restructured and parallelized to improve efficiency. The code was first optimized by combining two similar randomization routines, implementing a Fisher-Yates shuffling algorithm, and then parallelizing those routines. Tests of the parallelization and Fisher-Yates algorithmic improvements were performed on a variety of data sets ranging from 10 to 150 populations. All tested algorithms showed runtime reductions and a very close fit to the predicted speedups based on time-complexity calculations. In the case of 150 populations with 10,000 randomizations, data were analyzed 23 times faster. Conclusion Since the implementation of the new algorithms in late 2007, datasets have continued to

  9. Long-Distance Dispersal Shaped Patterns of Human Genetic Diversity in Eurasia.

    Science.gov (United States)

    Alves, Isabel; Arenas, Miguel; Currat, Mathias; Sramkova Hanulova, Anna; Sousa, Vitor C; Ray, Nicolas; Excoffier, Laurent

    2016-04-01

    Most previous attempts at reconstructing the past history of human populations did not explicitly take geography into account or considered very simple scenarios of migration and ignored environmental information. However, it is likely that the last glacial maximum (LGM) affected the demography and the range of many species, including our own. Moreover, long-distance dispersal (LDD) may have been an important component of human migrations, allowing fast colonization of new territories and preserving high levels of genetic diversity. Here, we use a high-quality microsatellite data set genotyped in 22 populations to estimate the posterior probabilities of several scenarios for the settlement of the Old World by modern humans. We considered models ranging from a simple spatial expansion to others including LDD and a LGM-induced range contraction, as well as Neolithic demographic expansions. We find that scenarios with LDD are much better supported by data than models without LDD. Nevertheless, we show evidence that LDD events to empty habitats were strongly prevented during the settlement of Eurasia. This unexpected absence of LDD ahead of the colonization wave front could have been caused by an Allee effect, either due to intrinsic causes such as an inbreeding depression built during the expansion or due to extrinsic causes such as direct competition with archaic humans. Overall, our results suggest only a relatively limited effect of the LGM contraction on current patterns of human diversity. This is in clear contrast with the major role of LDD migrations, which have potentially contributed to the intermingled genetic structure of Eurasian populations. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  10. Genetic recombination in Escherichia coli : II. Calculation of incorporation frequency and relative map distance by recombinant analysis

    NARCIS (Netherlands)

    Haan, P.G. de; Verhoef, C.

    1966-01-01

    In this paper a mathematical analysis based on the physical exchange of genetic material is presented for a four-factor cross. The incorporation frequency of donor markers and the relative map distances may be accurately estimated from the frequencies of the eight recombinant classes. The results ob

  11. Microsatellite genetic distances between oceanic populations of the humpback whale (Megaptera novaeangliae).

    Science.gov (United States)

    Valsecchi, E; Palsbøll, P; Hale, P; Glockner-Ferrari, D; Ferrari, M; Clapham, P; Larsen, F; Mattila, D; Sears, R; Sigurjonsson, J; Brown, M; Corkeron, P; Amos, B

    1997-04-01

    the fact that these alternative measures often contradict one another, we urge caution in the use of microsatellite data to quantify genetic distance.

  12. Landscape features influence gene flow as measured by cost-distance and genetic analyses: a case study for giant pandas in the Daxiangling and Xiaoxiangling Mountains

    OpenAIRE

    Wei Fuwen; Zhang Shanning; Meng Tao; Zhan Xiangjiang; Zhu Lifeng

    2010-01-01

    Abstract Background Gene flow maintains genetic diversity within a species and is influenced by individual behavior and the geographical features of the species' habitat. Here, we have characterized the geographical distribution of genetic patterns in giant pandas (Ailuropoda melanoleuca) living in four isolated patches of the Xiaoxiangling and Daxiangling Mountains. Three geographic distance definitions were used with the "isolation by distance theory": Euclidean distance (EUD), least-cost p...

  13. Genetic structure, mating system, and long-distance gene flow in heart of palm (Euterpe edulis Mart.).

    Science.gov (United States)

    Gaiotto, F A; Grattapaglia, D; Vencovsky, R

    2003-01-01

    We report a detailed analysis of the population genetic structure, mating system, and gene flow of heart of palm (Euterpe edulis Mart.-Arecaceae) in central Brazil. This palm is considered a keystone species because it supplies fruits for birds and rodents all year and is intensively harvested for culinary purposes. Two populations of this palm tree were examined, using 18 microsatellite loci. The species displays a predominantly outcrossed mating system (tm = 0.94), with a probability of full sibship greater than 70% within open-pollinated families. The following estimates of interpopulation genetic variation were calculated and found significant: FIT = 0.17, FIS = 0.12, FST = 0.06, and RST = 0.07. This low but significant level of interpopulation genetic variation indicates high levels of gene flow. Two adult trees were identified as likely seed parents (P > 99.9%) of juveniles located at a distance of 22 km. Gene flow over such distances has not been reported before for tropical tree species. The establishment and management of in situ genetic reserves or ex situ conservation and breeding populations for E. edulis should contemplate the collection of several hundreds open-pollinated maternal families from relatively few distant populations to maximize the genetic sampling of a larger number of pollen parents.

  14. Isolation by oceanic distance and spatial genetic structure in an overharvested international fishery

    NARCIS (Netherlands)

    Truelove, Nathan K.; Box, Stephen J.; Aiken, Karl A.; Blythe-Mallett, Azra; Boman, Erik M.; Booker, Catherine J.; Byfield, Tamsen T.; Cox, Courtney E.; Davis, Martha H.; Delgado, Gabriel A.; Glazer, Bob A.; Griffiths, Sarah M.; Kitson-Walters, Kimani; Kough, Andy S.; Pérez Enríquez, Ricardo; Preziosi, Richard F.; Roy, Marcia E.; Segura-García, Iris; Webber, Mona K.; Stoner, Allan W.

    2017-01-01

    Aim: A detailed understanding of spatial genetic structure (SGS) and the factors driving contemporary patterns of gene flow and genetic diversity are fundamental for developing conservation and management plans for marine fisheries. We performed a detailed study of SGS and genetic diversity

  15. Genetic isolation by distance among populations of the netted dog whelk Nassarius reticulatus (L.) along the European Atlantic coastline.

    Science.gov (United States)

    Couceiro, Lucía; Barreiro, Rodolfo; Ruiz, José M; Sotka, Erik E

    2007-01-01

    Estimates of the average distances by which marine larvae disperse are generally poorly described, despite the central role that larval dispersal plays in the demographic connectivity of populations across geographic space. Here, we describe the population genetic structure and average dispersal distance of the netted dog whelk Nassarius reticulatus (L.) (Mollusca, Gastropoda, Prosobranchia), a widespread member of European intertidal communities, using DNA sequence variation in a fragment of the mitochondrial gene cytochrome c oxidase subunit I (COI). An analysis of 156 individuals from 6 locations spread across approximately 1700 km of the European Atlantic coastline revealed weak and nonsignificant population structure (overall Phi(ST) = 0.00013). However, pairwise Phi(ST) values revealed a slight but significant increase in genetic isolation with geographic distance (IBD), suggesting that populations are not panmictic across the sampled geographic range. If we assume that the isolation by distance is maintained by a stable, stepping stone model of gene flow, then the slope of the IBD is consistent with an average larval dispersal distance of approximately 70 km per generation. The spatial scale of larval dispersal in N. reticulatus is consistent with the life cycle of the species (planktotrophic veliger lasting 30-60 days before competent to settle). A mismatch analysis of the COI sequences revealed a signature of an ancient demographic expansion that began 61 500-160,000 years ago, well before the most recent Pleistocene glaciation event. The greatest levels of genetic diversity occur within the middle latitudes of the whelk's geographic range, consistent with the notion that historic populations of N. reticulatus might have expanded northward and southward from the centrally located Bay of Biscay.

  16. Genetic evidence for high propagule pressure and long-distance dispersal in monk parakeet (Myiopsitta monachus) invasive populations.

    Science.gov (United States)

    Gonçalves da Silva, Anders; Eberhard, Jessica R; Wright, Timothy F; Avery, Michael L; Russello, Michael A

    2010-08-01

    The monk parakeet (Myiopsitta monachus) is a successful invasive species that does not exhibit life history traits typically associated with colonizing species (e.g., high reproductive rate or long-distance dispersal capacity). To investigate this apparent paradox, we examined individual and population genetic patterns of microsatellite loci at one native and two invasive sites. More specifically, we aimed at evaluating the role of propagule pressure, sexual monogamy and long-distance dispersal in monk parakeet invasion success. Our results indicate little loss of genetic variation at invasive sites relative to the native site. We also found strong evidence for sexual monogamy from patterns of relatedness within sites, and no definite cases of extra-pair paternity in either the native site sample or the examined invasive site. Taken together, these patterns directly and indirectly suggest that high propagule pressure has contributed to monk parakeet invasion success. In addition, we found evidence for frequent long-distance dispersal at an invasive site (approximately 100 km) that sharply contrasted with previous estimates of smaller dispersal distance made in the native range (approximately 2 km), suggesting long-range dispersal also contributes to the species' spread within the United States. Overall, these results add to a growing body of literature pointing to the important role of propagule pressure in determining, and thus predicting, invasion success, especially for species whose life history traits are not typically associated with invasiveness.

  17. Diverse spore rains and limited local mixing shaped fern genetic diversity in a recent habitat colonized by long-distance dispersal

    NARCIS (Netherlands)

    Groot, de G.A.; During, H.J.; Ansell, S.W.; Schneider, H.; Wubs, E.R.J.; Maas, J.W.; Korpelainen, H.; Erkens, R.H.J.

    2012-01-01

    Background and Aims: Populations established by long-distance colonization are expected to show low levels of genetic variation per population, but strong genetic differentiation among populations. Whether isolated populations indeed show this genetic signature of isolation depends on the amount and

  18. Genetic variation in Miscanthus x giganteus and the importance of estimating genetic distance tresholds for differentiating clones

    DEFF Research Database (Denmark)

    Glowacka, K; Clark, L; Adhikari, S;

    2015-01-01

    with samples of the parental species M. sacchariflorus and M. sinensis. Estimates of genotyping error rates were essential for distinguishing between experimental error and true genotypic differences among accessions. Given differences in estimated error rates and costs per marker for SSRs and RAD......-seq, the former is currently more cost-effective for determining if two accessions are genetically identical. We concluded that all of the Mxg legacy cultivars were derived via vegetative propagation from a single genet. In contrast with the Mxg legacy cultivars, genetic similarity to the type-specimen of eight...... new triploid Mxg progeny ranged from 0.46 to 0.56. Though genetic diversity among the Mxg legacy cultivars is critically low, new crosses can provide much-needed variation to growers...

  19. Migration and population genetics of the grain aphid Macrosiphum miscanti (Takahashi) in relation to the geographic distance and gene flow

    Institute of Scientific and Technical Information of China (English)

    GUO Wei; SHEN Zuorui; LI Zhihong; GAO Lingwang

    2005-01-01

    The population genetics of the grain aphid Macrosiphum miscanti (Takahashi) is analyzed by microsatellite markers.Samples collected from 15 locations in China have been examined at 5 polymorphic microsatellite loci. Overall, genetic diversity displays a relation between the migration and gene flow in the grain aphid: a free and frequent gene flow is found in the eastern populations, and gene isolation occurs in the two western populations, especially Datong population and Guiyang population. The natural barriers may present an insurmountable obstacle preventing gene flow and aphid migration. However, a spatial genetic differentiation between populations is correlated with their geographical separation, indicating the geographic differentiation may play an important role in shaping the genetic structure of M. miscanti populations. In addition, most populations of grain aphids are out of Hardy-Weinberg equilibrium and there is heterozygote deficit. Based on F statistics, the average genetic differentiation among different geographical populations is relatively low. It seems that the long distance migration of the grain aphid may enhance gene flow and decrease genetic differentiation among different populations.

  20. Influence of habitat discontinuity, geographical distance, and oceanography on fine-scale population genetic structure of copper rockfish (Sebastes caurinus).

    Science.gov (United States)

    Johansson, M L; Banks, M A; Glunt, K D; Hassel-Finnegan, H M; Buonaccorsi, V P

    2008-07-01

    The copper rockfish is a benthic, nonmigratory, temperate rocky reef marine species with pelagic larvae and juveniles. A previous range-wide study of the population-genetic structure of copper rockfish revealed a pattern consistent with isolation-by-distance. This could arise from an intrinsically limited dispersal capability in the species or from regularly-spaced extrinsic barriers that restrict gene flow (offshore jets that advect larvae offshore and/or habitat patchiness). Tissue samples were collected along the West Coast of the contiguous USA between Neah Bay, WA and San Diego, CA, with dense sampling along Oregon. At the whole-coast scale (approximately 2200 km), significant population subdivision (F(ST) = 0.0042), and a significant correlation between genetic and geographical distance were observed based on 11 microsatellite DNA loci. Population divergence was also significant among Oregon collections (approximately 450 km, F(ST) = 0.001). Hierarchical amova identified a weak but significant 130-km habitat break as a possible barrier to gene flow within Oregon, across which we estimated that dispersal (N(e)m) is half that of the coast-wide average. However, individual-based Bayesian analyses failed to identify more than a single population along the Oregon coast. In addition, no correlation between pairwise population genetic and geographical distances was detected at this scale. The offshore jet at Cape Blanco was not a significant barrier to gene flow in this species. These findings are consistent with low larval dispersal distances calculated in previous studies on this species, support a mesoscale dispersal model, and highlight the importance of continuity of habitat and adult population size in maintaining gene flow.

  1. Invasive chloroplast population genetics of Mikania micrantha in China: no local adaptation and negative correlation between diversity and geographic distance

    Directory of Open Access Journals (Sweden)

    Ting Wang

    2016-09-01

    Full Text Available Two fundamental questions on how invasive species are able to rapidly colonize novel habitat have emerged. One asks whether a negative correlation exists between the genetic diversity of invasive populations and their geographic distance from the origin of introduction. The other is whether selection on the chloroplast genome is important driver of adaptation to novel soil environments. Here, we addressed these questions in a study of the noxious invasive weed, Mikania micrantha, which has rapidly expanded in to southern China after being introduced to Hong Kong in 1884. Seven cpSSRs were used to investigate population genetics in twenty-eight populations of M. micrantha, which produced thirty-nine loci. The soil compositions for these populations, including Mg abundance, were measured. The results showed that M. micrantha possessed relatively high cpSSR variation and differentiation among populations. Multiple diversity indices were quantified, and none was significantly correlated with distance from the origin of introduction. No evidence for isolation by distance, significant spatial structure, bottlenecks, nor linkage disequilibrium was detected. We also were unable to identify loci on the chloroplast genome that exhibited patterns of differentiation that would suggest adaptive evolution in response to soil attributes. Soil Mg has only a genome-wide effect instead of being a selective factor, which highlighted the association between Mg and the successful invasion. This study characterizes the role of the chloroplast genome of M. micrantha during its recent invasion of southern China.

  2. Invasive Chloroplast Population Genetics of Mikania micrantha in China: No Local Adaptation and Negative Correlation between Diversity and Geographic Distance.

    Science.gov (United States)

    Wang, Ting; Wang, Zhen; Chen, Guopei; Wang, Chunbo; Su, Yingjuan

    2016-01-01

    Two fundamental questions on how invasive species are able to rapidly colonize novel habitat have emerged. One asks whether a negative correlation exists between the genetic diversity of invasive populations and their geographic distance from the origin of introduction. The other is whether selection on the chloroplast genome is important driver of adaptation to novel soil environments. Here, we addressed these questions in a study of the noxious invasive weed, Mikania micrantha, which has rapidly expanded in to southern China after being introduced to Hong Kong in 1884. Seven chloroplast simple sequence repeats (cpSSRs) were used to investigate population genetics in 28 populations of M. micrantha, which produced 39 loci. The soil compositions for these populations, including Mg abundance, were measured. The results showed that M. micrantha possessed relatively high cpSSR variation and differentiation among populations. Multiple diversity indices were quantified, and none was significantly correlated with distance from the origin of introduction. No evidence for "isolation by distance," significant spatial structure, bottlenecks, nor linkage disequilibrium was detected. We also were unable to identify loci on the chloroplast genome that exhibited patterns of differentiation that would suggest adaptive evolution in response to soil attributes. Soil Mg had only a genome-wide effect instead of being a selective factor, which highlighted the association between Mg and the successful invasion. This study characterizes the role of the chloroplast genome of M. micrantha during its recent invasion of southern China.

  3. Comparative epigenetic and genetic spatial structure of the perennial herb Helleborus foetidus: Isolation by environment, isolation by distance, and functional trait divergence.

    Science.gov (United States)

    Herrera, Carlos M; Medrano, Mónica; Bazaga, Pilar

    2017-08-16

    Epigenetic variation can play a role in local adaptation; thus, there should be associations among epigenetic variation, environmental variation, and functional trait variation across populations. This study examines these relationships in the perennial herb Helleborus foetidus (Ranunculaceae). Plants from 10 subpopulations were characterized genetically (AFLP, SSR markers), epigenetically (MSAP markers), and phenotypically (20 functional traits). Habitats were characterized using six environmental variables. Isolation-by-distance (IBD) and isolation-by-environment (IBE) patterns of genetic and epigenetic divergence were assessed, as was the comparative explanatory value of geographical and environmental distance as predictors of epigenetic, genetic, and functional differentiation. Subpopulations were differentiated genetically, epigenetically, and phenotypically. Genetic differentiation was best explained by geographical distance, while epigenetic differentiation was best explained by environmental distance. Divergence in functional traits was correlated with environmental and epigenetic distances, but not with geographical and genetic distances. Results are compatible with the hypothesis that epigenetic IBE and functional divergence reflected responses to environmental variation. Spatial analyses simultaneously considering epigenetic, genetic, phenotypic and environmental information provide a useful tool to evaluate the role of environmental features as drivers of natural epigenetic variation between populations. © 2017 Botanical Society of America.

  4. Population structure of the Chenchu and other south Indian tribal groups: relationships between genetic, anthropometric, dermatoglyphic, geographic, and linguistic distances.

    Science.gov (United States)

    Sirajuddin, S M; Duggirala, R; Crawford, M H

    1994-10-01

    We describe the genetic structure and interrelationships of nine south Indian tribal groups (seven from Andhra Pradesh and two from the adjoining states of Tamil Nadu and Kerala) using seven polymorphic loci (ABO, MN, RH, PGM, ACP, PGD, and LDH). R matrix analysis indicates that the Andhra Pradesh tribes are clustered and that the Kadar and Irula are genetically isolated from them. This dispersion of populations has been explained by the combination of relatively high frequencies of the alleles RH D and MN M in the Kadar and the relatively high proportions of the allele PGM*2 in the Irula. The Mahaboobnagar Chenchu subgroup is isolated from other Telugu-speaking groups because of high frequencies of the PGM*1 and ACP*A alleles. The regression of mean per locus heterozygosity (H) on distance from the gene frequency centroid (rii) reveals considerable levels of external gene flow among the Lambadi, the Yerukula, and the two Chenchu subgroups and more homogeneity in the Kolam, Koya, Yanadi, Irula, and Kadar. Mantel statistics were used to assess the relative effects of nonbiological processes (i.e., language and geography) on the morphological and genetic patterns of these subdivided populations. The significance of correlations was determined between different data sets (genetic, dermatoglyphic, anthropometric, geographic, and linguistic) at three levels involving nine, six, and five populations. Although multiple correlation analysis reveals significant combined effects of geography and language on genetics, anthropometrics, and dermatoglyphics, highly significant partial correlations suggest strong effects of geography on both anthropometry and genetics. Our analysis indicates that geographic factors have an overwhelming effect on the genetic differentiation of the south Indian tribal groups.

  5. Hierarchical structure of genetic distances: Effects of matrix size, spatial distribution and correlation structure among gene frequencies

    Directory of Open Access Journals (Sweden)

    Flávia Melo Rodrigues

    1998-06-01

    Full Text Available Geographic structure of genetic distances among local populations within species, based on allozyme data, has usually been evaluated by estimating genetic distances clustered with hierarchical algorithms, such as the unweighted pair-group method by arithmetic averages (UPGMA. The distortion produced in the clustering process is estimated by the cophenetic correlation coefficient. This hierarchical approach, however, can fail to produce an accurate representation of genetic distances among populations in a low dimensional space, especially when continuous (clinal or reticulate patterns of variation exist. In the present study, we analyzed 50 genetic distance matrices from the literature, for animal taxa ranging from Platyhelminthes to Mammalia, in order to determine in which situations the UPGMA is useful to understand patterns of genetic variation among populations. The cophenetic correlation coefficients, derived from UPGMA based on three types of genetic distance coefficients, were correlated with other parameters of each matrix, including number of populations, loci, alleles, maximum geographic distance among populations, relative magnitude of the first eigenvalue of covariance matrix among alleles and logarithm of body size. Most cophenetic correlations were higher than 0.80, and the highest values appeared for Nei's and Rogers' genetic distances. The relationship between cophenetic correlation coefficients and the other parameters analyzed was defined by an "envelope space", forming triangles in which higher values of cophenetic correlations are found for higher values in the parameters, though low values do not necessarily correspond to high cophenetic correlations. We concluded that UPGMA is useful to describe genetic distances based on large distance matrices (both in terms of elevated number of populations or alleles, when dimensionality of the system is low (matrices with large first eigenvalues or when local populations are separated

  6. Comparative Study of Nei�s D with other Genetic Distance Measures between Barak Valley Muslims and other Nations for ABO Locus

    Directory of Open Access Journals (Sweden)

    Supriyo CHAKRABORTY

    2012-02-01

    Full Text Available Quantification of the genetic distance between populations is essential in many genetic research programs. Several formulae were proposed for the estimation of genetic distance between populations using gene frequency data. But the selection of a suitable measure for estimating genetic distance between real-world human populations is a very difficult task despite the widely used measure Nei�s D. The present study was undertaken to estimate the genetic distance between Barak Valley Muslims (BVM and other twenty-four nations using seven different measures with ABO blood group gene frequency data for comparative analysis and to estimate the correlation coefficients between distance measures and to work out the linear regression equations. Seven genetic distance measures namely Nei�s D, Nei�s Nm, La, Nei�s Da, Dc, Re and Nei�s Ne were estimated between BVM and other 24 nations enroute the journey of mankind from Africa that commenced about 200,000 years ago (www.bradshawfoundation.com. Correlation coefficients between Nei�s D with other measures were estimated to find out which other genetic distance measures were closely related to Nei�s D. Nei�s D showed highly significant (p=0.01 positive correlation with Cavalli-Sforza and Edwards chord distance Dc (0.90, Reynolds Re (0.90, Nei�s Da (0.74 and Nei�s Ne (0.63 but negative correlation with Nei�s Nm and La. Linear regression equations of Nei�s D with other distance measures were estimated as Da = -0.80 + 1.34D, Dc = 1.91 + 4.44D, Re = -0.51 + 0.24D and Ne = -7.60 + 1.30D.

  7. Comparative Study of Nei�s D with other Genetic Distance Measures between Barak Valley Muslims and other Nations for ABO Locus

    Directory of Open Access Journals (Sweden)

    Supriyo CHAKRABORTY

    2012-02-01

    Full Text Available Quantification of the genetic distance between populations is essential in many genetic research programs. Several formulae were proposed for the estimation of genetic distance between populations using gene frequency data. But the selection of a suitable measure for estimating genetic distance between real-world human populations is a very difficult task despite the widely used measure Neis D. The present study was undertaken to estimate the genetic distance between Barak Valley Muslims (BVM and other twenty-four nations using seven different measures with ABO blood group gene frequency data for comparative analysis and to estimate the correlation coefficients between distance measures and to work out the linear regression equations. Seven genetic distance measures namely Neis D, Neis Nm, La, Neis Da, Dc, Re and Neis Ne were estimated between BVM and other 24 nations enroute the journey of mankind from Africa that commenced about 200,000 years ago (www.bradshawfoundation.com. Correlation coefficients between Neis D with other measures were estimated to find out which other genetic distance measures were closely related to Neis D. Neis D showed highly significant (p=0.01 positive correlation with Cavalli-Sforza and Edwards chord distance Dc (0.90, Reynolds Re (0.90, Neis Da (0.74 and Neis Ne (0.63 but negative correlation with Neis Nm and La. Linear regression equations of Neis D with other distance measures were estimated as Da = -0.80 + 1.34D, Dc = 1.91 + 4.44D, Re = -0.51 + 0.24D and Ne = -7.60 + 1.30D.

  8. Mother-offspring distances reflect sex differences in fine-scale genetic structure of eastern grey kangaroos.

    Science.gov (United States)

    King, Wendy J; Garant, Dany; Festa-Bianchet, Marco

    2015-05-01

    Natal dispersal affects life history and population biology and causes gene flow. In mammals, dispersal is usually male-biased so that females tend to be philopatric and surrounded by matrilineal kin, which may lead to preferential associations among female kin. Here we combine genetic analyses and behavioral observations to investigate spatial genetic structure and sex-biased dispersal patterns in a high-density population of mammals showing fission-fusion group dynamics. We studied eastern grey kangaroos (Macropus giganteus) over 2 years at Wilsons Promontory National Park, Australia, and found weak fine-scale genetic structure among adult females in both years but no structure among adult males. Immature male kangaroos moved away from their mothers at 18-25 months of age, while immature females remained near their mothers until older. A higher proportion of male (34%) than female (6%) subadults and young adults were observed to disperse, although median distances of detected dispersals were similar for both sexes. Adult females had overlapping ranges that were far wider than the maximum extent of spatial genetic structure found. Female kangaroos, although weakly philopatric, mostly encounter nonrelatives in fission-fusion groups at high density, and therefore kinship is unlikely to strongly affect sociality.

  9. Mother–offspring distances reflect sex differences in fine-scale genetic structure of eastern grey kangaroos

    Science.gov (United States)

    King, Wendy J; Garant, Dany; Festa-Bianchet, Marco

    2015-01-01

    Natal dispersal affects life history and population biology and causes gene flow. In mammals, dispersal is usually male-biased so that females tend to be philopatric and surrounded by matrilineal kin, which may lead to preferential associations among female kin. Here we combine genetic analyses and behavioral observations to investigate spatial genetic structure and sex-biased dispersal patterns in a high-density population of mammals showing fission–fusion group dynamics. We studied eastern grey kangaroos (Macropus giganteus) over 2 years at Wilsons Promontory National Park, Australia, and found weak fine-scale genetic structure among adult females in both years but no structure among adult males. Immature male kangaroos moved away from their mothers at 18–25 months of age, while immature females remained near their mothers until older. A higher proportion of male (34%) than female (6%) subadults and young adults were observed to disperse, although median distances of detected dispersals were similar for both sexes. Adult females had overlapping ranges that were far wider than the maximum extent of spatial genetic structure found. Female kangaroos, although weakly philopatric, mostly encounter nonrelatives in fission–fusion groups at high density, and therefore kinship is unlikely to strongly affect sociality. PMID:26045958

  10. Genome-wide patterns of genetic distances reveal candidate Loci contributing to human population-specific traits.

    Science.gov (United States)

    de Magalhães, João Pedro; Matsuda, Alex

    2012-03-01

    Modern humans originated in Africa before migrating across the world with founder effects and adaptations to new environments contributing to their present phenotypic diversity. Determining the genetic basis of differences between populations may provide clues about our evolutionary history and may have clinical implications. Herein, we develop a method to detect genes and biological processes in which populations most differ by calculating the genetic distance between modern populations and a hypothetical ancestral population. We apply our method to large-scale single nucleotide polymorphism (SNP) data from human populations of African, European and Asian origin. As expected, ancestral alleles were more conserved in the African populations and we found evidence of high divergence in genes previously suggested as targets of selection related to skin pigmentation, immune response, senses and dietary adaptations. Our genome-wide scan also reveals novel candidates for contributing to population-specific traits. These include genes related to neuronal development and behavior that may have been influenced by cultural processes. Moreover, in the African populations, we found a high divergence in genes related to UV protection and to the male reproductive system. Taken together, these results confirm and expand previous findings, providing new clues about the evolution and genetics of human phenotypic diversity. © 2011 The Authors Annals of Human Genetics © 2011 Blackwell Publishing Ltd/University College London.

  11. Genetic structuring of the moss Pseudoscleropodium purum sampled at different distances from a pollution source.

    Science.gov (United States)

    Boquete, M Teresa; Spagnuolo, Valeria; Fernández, J Ángel; Aboal, Jesús R; Imperatore, Ivana; Giordano, Simonetta

    2016-12-01

    In this study, we used amplified fragment length polymorphism analysis to investigate the genetic structure of the terrestrial moss Pseudoscleropodium purum (Hedw.) M. Fleish. naturally exposed to different levels of atmospheric deposition of heavy metals. We also determined the heavy metal concentrations in samples of this moss to evaluate whether there was a relationship between atmospheric pollution and population genetic diversity. A low level of genetic diversity and a limited gene flow among populations were observed which is in accordance to the prevalence of asexual reproduction in this species. In addition, no significant correlation was found between metal content and gene diversity in P. purum, probably because of the common history of the sampled populations and/or to the lack of a drastic reduction of the size of the population; nonetheless, a clear genetic structure was evident in relation to the existing pollution gradient. Thus, based on the results of the principal coordinate analysis and Bayesian analysis of the genotypes, the mixed structure of the second most polluted population would suggest an ongoing differentiation of metal-tolerant genotypes in the most polluted sites of the sampling area.

  12. Genetic recombination in Escherichia coli : I. Relation between linkage of unselected markers and map distance

    NARCIS (Netherlands)

    Verhoef, C.; Haan, P.G. de

    1966-01-01

    A relation between linkage frequency of an unselected marker and transfer time based on a physical exchange of genetic material was developed for Escherichia coli crosses. Crosses performed under standardised conditions have shown that the relation was valid. The linkage frequency is determined by t

  13. Genetic Distance and Heterosis through Evaluation Index in the Silkworm, Bombyx mori (L.

    Directory of Open Access Journals (Sweden)

    Ebrahim Talebi

    2009-01-01

    Full Text Available Problem statement: Synthesis of new-gene combinations by genetic manipulation is one of the powerful tools in exploiting the commercial qualities of plants and animals. Hybrid performance is evaluated from extensive yield trials that are costly and time consuming. Approach: Four silkworm races belonging to two different voltine groups (two multivoltine races namely Pure Mysore and Nistari and two bivoltine races namely C108 and NB4D2 and the twelve regular and reciprocal hybrids derived from them were reared under standard laboratory condition analyzing six quantitative traits namely cocoon weight, shell weight, shell ratio, filament length, denier and renditta. The data of the pure races was analysed for the estimation of evaluation index to study the genetic divergence between the races, where as evaluation index, heterosis and overdominance effects were studied in twelve hybrid combinations. Results: Varied heterotic effects were observed for different traits for hybrid combination. Cocoon weight and shell weight has maximum heterosis over the mid parent in Pure Mysore × Nistari (27 and 42% respectively, whereas C108 × Nistari have shown maximum shell ratio (30% among the hybrids. The maximum filament length for heterosis was observed in the Nistari × Pure Mysore. Heterosis for cocoon weight, shell weight, shell ratio, filament length, denier and renditta based on evaluation index confirmed the above results. Conclusion: The investigation indicates that optimum level of genetic divergence between parents is necessary to obtain heterosis in F1 generation.

  14. CONTRIBUTION OF MARITAL DISTANCE TO COMMUNITY INBREEDING, HOMOZYGOSIS, AND REPRODUCTIVE WASTAGE FOR RECESSIVELY INHERITED GENETIC DISORDERS IN MADHYA PRADESH, INDIA

    Directory of Open Access Journals (Sweden)

    R S Balgir

    2013-11-01

    Full Text Available Background: Recessively inherited genetic disorders such as sickle cell anemia and β-thalassemia are commonly encountered in heterozygous and homozygous form in India. These hemolytic disorders cause a high degree of reproductive wastage in vulnerable communities. Inbreeding is usually the mating between two related individuals. Homozygosis is antagonistic process of heterosis. Purpose: This study was aimed at finding reproductive outcome in carrier couples of sickle cell disease, and β-thalassemia in terms of reproductive wastage in relation to varied marital distance between partners in Madhya Pradesh. Methods: A total of 107 (35 and 72, respectively carrier couples of β-thalassemia major and sickle cell anemia with confirmed affected offspring after taking detailed reproductive history were studied following the standard methodology in a tertiary hospital in Central India during March 2010 to February 2013. Results: A majority of sickle cell and b-thalassemia carrier couples (77.8% and 65.7%, respectively had married within physical distance of radius less than 50 kms. away from their native places. It was found that as the marital distance between two carrier partners of above disorders decreases, the number of abortions, still-births, neonatal mortality, infant mortality, and mortality under 10 years age increases, and vice versa, implicating inbreeding and homozygosis. The overall reproductive wastage of 28.2% and 18.6% was recorded in carrier couples of sickle cell disease and β-thalassemia, respectively. Conclusions: Relative small population size clubbed with small marital distance leads to inbreeding resulting in homozygosity which increases chances of affected offspring by recessive or deleterious traits and contributes to decreased fitness of a couple or population in Central India.

  15. Comparison of the genetic relationship between nine Cephalopod species based on cluster analysis of karyotype evolutionary distance

    Directory of Open Access Journals (Sweden)

    Jin-hai Wang

    2017-07-01

    Full Text Available Karyotype analysis was carried out on gill cells of three species of octopods using a conventional air-drying method. The karyotype results showed that all the three species have the same diploid chromosome number, 2n=60, but with different karyograms as 2n=38M+6SM+8ST+8T, FN (fundamental number=104 (Cistopus chinensis Zheng et al., 2012, 2n=42M+6SM+4ST+8T, FN=108 (Octopus minor (Sasaki, 1920 and 2n=32M+16SM+12T, FN=108 (Amphioctopus fangsiao (d’Orbigny, 1839–1841. These findings were combined with data from earlier studies to infer the genetic relationships between nine species via cluster analysis using the karyotype evolutionary distance (De and resemblance-near coefficient (λ. The resulting tree revealed a clear distinction between different families and orders which was substantially consistent with molecular phylogenies. The smallest intraspecific evolutionary distance (De=0.2013, 0.2399 and largest resemblance-near coefficient (λ=0.8184, 0.7871 appeared between O. minor and C. chinensis, and Sepia esculenta Hoyle, 1885 and S. lycidas Gray, 1849, respectively, indicating that these species have the closest relationship. The largest evolutionary gap appeared between species with complicated karyotypes and species with simple karyotypes. Cluster analysis of De and λ provides information to supplement traditional taxonomy and molecular systematics, and it would serve as an important auxiliary for routine phylogenetic study.

  16. Investigation of Genetic Distance among Parental Lines of Hybrid Rice Based on Cluster Analysis of Morphological Traits

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    A. Baluch-Zehi

    2013-06-01

    Full Text Available conditions. Thus, these varieties could be suitable option for yield increase and an effective step toward food security. Selection of parental lines has essential role in developing ideal combinations. Therefore, it is essential to study the relationship and genetic diversity among parental lines in hybrid rice. Sixteen hybrid rice parental lines including 6 restorer lines (Poya, Sepidrud, Pajohesh, R2, R9 and IR50 and 5 CMS lines (Neda, Nemat, Dasht, Champa and Amol 3 with their 5 maintainers were studied at Research Farm of Sari Agricultural Sciences and Natural Resources University during 2011. Analysis of variance showed significant variations for all of the studied traits, which shows great diversity among the genotypes. The number of fertile tillers and length to width ratio of grain showed positive and significant correlation with yield. But, grain width showed negative and significant correlation with yield. Results of principal component analysis revealed that 3 components explained 75.64% of the total variations. Cluster analysis at 15 genetic distance criteria grouped genotypes in 4 clusters. In exploration of heterosis phenomenon, parents must be far away from each other. So, the results of this study suggested crosses between CMS lines of Neda A, Nemat A and Champa A with each of restorer lines R9, R2, IR50 and Poya for experimental hybrid seed production.

  17. Argument-predicate distance as a filter for enhancing precision in extracting predications on the genetic etiology of disease

    Science.gov (United States)

    Masseroli, Marco; Kilicoglu, Halil; Lang, François-Michel; Rindflesch, Thomas C

    2006-01-01

    Background Genomic functional information is valuable for biomedical research. However, such information frequently needs to be extracted from the scientific literature and structured in order to be exploited by automatic systems. Natural language processing is increasingly used for this purpose although it inherently involves errors. A postprocessing strategy that selects relations most likely to be correct is proposed and evaluated on the output of SemGen, a system that extracts semantic predications on the etiology of genetic diseases. Based on the number of intervening phrases between an argument and its predicate, we defined a heuristic strategy to filter the extracted semantic relations according to their likelihood of being correct. We also applied this strategy to relations identified with co-occurrence processing. Finally, we exploited postprocessed SemGen predications to investigate the genetic basis of Parkinson's disease. Results The filtering procedure for increased precision is based on the intuition that arguments which occur close to their predicate are easier to identify than those at a distance. For example, if gene-gene relations are filtered for arguments at a distance of 1 phrase from the predicate, precision increases from 41.95% (baseline) to 70.75%. Since this proximity filtering is based on syntactic structure, applying it to the results of co-occurrence processing is useful, but not as effective as when applied to the output of natural language processing. In an effort to exploit SemGen predications on the etiology of disease after increasing precision with postprocessing, a gene list was derived from extracted information enhanced with postprocessing filtering and was automatically annotated with GFINDer, a Web application that dynamically retrieves functional and phenotypic information from structured biomolecular resources. Two of the genes in this list are likely relevant to Parkinson's disease but are not associated with this disease

  18. Genetic distance and heterogenecity between quasispecies is a critical predictor to IFN response in Egyptian patients with HCV genotype-4

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    Fouad Inas

    2007-02-01

    Full Text Available Abstract Background HCV is one of the major health problems in Egypt, where it is highly prevalent. Genotype 4 is the most common genotype of HCV and its response to treatment is still a controversy. Methods HCV genotype 4 quasispecies diversity within the 5' untranslated region (5'UTR was studied in a series of 22 native Egyptian patients with chronic hepatitis C virus with no previous treatment who satisfied all NIH criteria for combined treatment of pegylated IFN and ribavirine and was correlated with the outcome of treatment. The study also included 7 control patients with no antiviral treatment. HCV sequencing was done using the TRUGENE HCV 5-NC genotyping kit. Results At the 48th week of treatment, 15 patients (68% showed virological response. Whereas HCV-RNA was still detected in 7 patients (32% in this period; of those, 6 experienced a partial virological response followed by viral breakthrough during treatment. Only one patient did not show any virological or chemical response. The four females included in this study were all responders. There was a significant correlation between the response rate and lower fibrosis (p = 0.026 as well as the total number of mutation spots (including all the insertions, deletions, transitions and transversions (p = 0.007, p = 0.035. Conclusion Patients who responded to interferon treatment had statistically significant less number in both transitions (p = 0.007 and the genetic distances between the quasispecies (p = 0.035. So, viral genetic complexity and variability may play a role in the response to IFN treatment. The consensus alignment of all three groups revealed no characteristic pattern among the three groups. However, the G to A transitions at 160 was observed among non responders who need further study to confirm this observation.

  19. Extracting samples of high diversity from thematic collections of large gene banks using a genetic-distance based approach.

    Science.gov (United States)

    Pessoa-Filho, Marco; Rangel, Paulo H N; Ferreira, Marcio E

    2010-06-24

    Breeding programs are usually reluctant to evaluate and use germplasm accessions other than the elite materials belonging to their advanced populations. The concept of core collections has been proposed to facilitate the access of potential users to samples of small sizes, representative of the genetic variability contained within the gene pool of a specific crop. The eventual large size of a core collection perpetuates the problem it was originally proposed to solve. The present study suggests that, in addition to the classic core collection concept, thematic core collections should be also developed for a specific crop, composed of a limited number of accessions, with a manageable size. The thematic core collection obtained meets the minimum requirements for a core sample - maintenance of at least 80% of the allelic richness of the thematic collection, with, approximately, 15% of its size. The method was compared with other methodologies based on the M strategy, and also with a core collection generated by random sampling. Higher proportions of retained alleles (in a core collection of equal size) or similar proportions of retained alleles (in a core collection of smaller size) were detected in the two methods based on the M strategy compared to the proposed methodology. Core sub-collections constructed by different methods were compared regarding the increase or maintenance of phenotypic diversity. No change on phenotypic diversity was detected by measuring the trait "Weight of 100 Seeds", for the tested sampling methods. Effects on linkage disequilibrium between unlinked microsatellite loci, due to sampling, are discussed. Building of a thematic core collection was here defined by prior selection of accessions which are diverse for the trait of interest, and then by pairwise genetic distances, estimated by DNA polymorphism analysis at molecular marker loci. The resulting thematic core collection potentially reflects the maximum allele richness with the smallest

  20. Extracting samples of high diversity from thematic collections of large gene banks using a genetic-distance based approach

    Directory of Open Access Journals (Sweden)

    Rangel Paulo HN

    2010-06-01

    Full Text Available Abstract Background Breeding programs are usually reluctant to evaluate and use germplasm accessions other than the elite materials belonging to their advanced populations. The concept of core collections has been proposed to facilitate the access of potential users to samples of small sizes, representative of the genetic variability contained within the gene pool of a specific crop. The eventual large size of a core collection perpetuates the problem it was originally proposed to solve. The present study suggests that, in addition to the classic core collection concept, thematic core collections should be also developed for a specific crop, composed of a limited number of accessions, with a manageable size. Results The thematic core collection obtained meets the minimum requirements for a core sample - maintenance of at least 80% of the allelic richness of the thematic collection, with, approximately, 15% of its size. The method was compared with other methodologies based on the M strategy, and also with a core collection generated by random sampling. Higher proportions of retained alleles (in a core collection of equal size or similar proportions of retained alleles (in a core collection of smaller size were detected in the two methods based on the M strategy compared to the proposed methodology. Core sub-collections constructed by different methods were compared regarding the increase or maintenance of phenotypic diversity. No change on phenotypic diversity was detected by measuring the trait "Weight of 100 Seeds", for the tested sampling methods. Effects on linkage disequilibrium between unlinked microsatellite loci, due to sampling, are discussed. Conclusions Building of a thematic core collection was here defined by prior selection of accessions which are diverse for the trait of interest, and then by pairwise genetic distances, estimated by DNA polymorphism analysis at molecular marker loci. The resulting thematic core collection

  1. Evaluation of reproductive barriers and realisation of interspecific hybridisations depending on genetic distances between species in the genus Helleborus.

    Science.gov (United States)

    Meiners, J; Winkelmann, T

    2012-07-01

    The genus Helleborus comprises 22 species, which are allocated to six sections. H. x hybridus and H. niger, which belong to different Helleborus sections, are economically important ornamentals. Several other species with minor impact exhibit interesting features, e.g. flower size, flower colour, foliage, scent and disease resistance, which should be introgressed into H. x hybridus or H. niger through interspecific hybridisation. The aims of this study were to investigate whether and which kind of hybridisation barriers occur in crosses between Helleborus species and if they differ in their manifestations, depending on the genetic distance of the respective partners. In order to obtain interspecific hybrids despite crossing barriers, a method to overcome these barriers should be developed. Crossing barriers in Helleborus were localised as predominantly post-zygotic according to in situ pollen tube staining with aniline blue. For certain crosses, pre-zygotic barriers could also be assumed, but pollen tube growth was not totally inhibited. Therefore, embryo rescue techniques via ovule culture were established to overcome the post-zygotic barriers. Ovules were isolated from maternal plants 5-7 weeks after pollination in most cases and then cultured in vitro. Overall, 219 hybrids were successfully obtained, of which 16 were derived from inter-sectional crosses. Hybrids were verified by flow cytometry and/or by molecular DNA markers. © 2012 German Botanical Society and The Royal Botanical Society of the Netherlands.

  2. Estimation of genetic parameters for racing speed at different distances in young and adult Spanish Trotter horses using the random regression model.

    Science.gov (United States)

    Gómez, M D; Menendez-Buxadera, A; Valera, M; Molina, A

    2010-10-01

    A total of 71 522 records (from 3154 horses) with the times per kilometre (TPK), recorded in Spanish Trotter horses (individual races) from racing performances held from 1991 to 2007, were available for this study. The TPK values for the different age groups (young and adult horses) and different distances (1600-2700 m) were considered as different traits, and a bi character random regression model (RRM) was applied to estimate the (co)variance components throughout the trajectory of age groups and distances. The following effects were considered as fixed: the combination of hippodrome-date of race (404 levels); sex of the animals (3 levels); type of start (2 levels) and a fixed regression of Legendre polynomials (order 2). Those considered as random effects were the random regression Legendre polynomial (order 1) for animals (9201 animals in the pedigree); the individual environment permanent (3154 animals with data) and the driver (n = 957 levels). The residual variance was considered as heterogeneous with two classes (ages). The heritability estimated by distance ranged from 0.12 to 0.34, with a different trajectory for the two age groups. Within each age group, the genetic correlations between adjacent distances were high (>0.90), but decreased when the differences between them were over 400 metres for both age groups. The genetic correlations for the same distance across the age groups ranged from 0.47 to 0.78. Accordingly, the analysed trait (TPK) can be considered as positive genetic correlated but as different traits along the trajectory of distance and age. Therefore, some re-ranking should be expected in the breeding value of the horses at different characteristics of the racing. The use of RRM is recommended because it allows us to estimate the breeding value along the whole trajectory of race competition.

  3. Phylogeography of postglacial range expansion in Juglans mandshurica (Juglandaceae) reveals no evidence of bottleneck, loss of genetic diversity, or isolation by distance in the leading-edge populations.

    Science.gov (United States)

    Wang, Wen-Ting; Xu, Bing; Zhang, Da-Yong; Bai, Wei-Ning

    2016-09-01

    The past studies of postglacial recolonization patterns in high latitude regions have revealed a significant role of dispersal capacity in shaping the genetic diversity and population structure of temperate trees. However, most of these studies have focused on species with long-distance dispersal followed by exponential population growth and were therefore unable to reveal the patterns in the case of a gradual expansion. Here we studied the impacts of postglacial range expansions on the distribution of genetic diversity in the Manchurian walnut (Juglans mandshurica), a common tree of East Asian cool-temperate deciduous forests that apparently lacks long-distance seed dispersal ability. The genetic diversity and structure of 19 natural walnut populations in Northeast China and the Korean Peninsula were examined using 17 nuclear simple sequence repeat (SSR) loci. Potential habitats under current and past climatic conditions were predicted using the ecological niche modelling (ENM) method. Bayesian clustering analysis revealed three groups, which were inferred to have diverged through multiple glacial-interglacial cycles in multiple refugia during the Quaternary Period. ENM estimated a southward range shift at the LGM, but high suitability scores still occurred in the western parts of the Changbai Mountains (Northeast China), the Korean peninsula and the exposed seafloor of the Yellow Sea. In contrast to most other cool-temperate trees co-occurring in the same region, the Manchurian walnut did not show any evidence of a population bottleneck, loss of genetic diversity or isolation by distance during the postglacial expansion. Our study clearly indicates that current northern populations originated from one glacial lineage and recolonization via a gradually advancing front due to the lack of a long-distance seed dispersal mechanism led to no latitudinal decrease in genetic diversity.

  4. Representing distance, consuming distance

    DEFF Research Database (Denmark)

    Larsen, Gunvor Riber

    to mobility and its social context. Such an understanding can be approached through representations, as distance is being represented in various ways, most noticeably in maps and through the notions of space and Otherness. The question this talk subsequently asks is whether these representations of distance...... are being consumed in the contemporary society, in the same way as places, media, cultures and status are being consumed (Urry 1995, Featherstone 2007). An exploration of distance and its representations through contemporary consumption theory could expose what role distance plays in forming...... are present in theoretical and empirical elaborations on mobility, but these remain largely implicit and unchallenged (Bauman 1998). This talk will endeavour to unmask distance as a theoretical entity by exploring ways in which distance can be understood and by discussing distance through its representations...

  5. Multilocus phylogeography (mitochondrial, autosomal and Z-chromosomal loci) and genetic consequence of long-distance male dispersal in Black-throated tits (Aegithalos concinnus).

    Science.gov (United States)

    Dai, C; Wang, W; Lei, F

    2013-05-01

    Multilocus data from the different genomes are essential to understand the phylogeographic history of species, particularly when a species has the male-biased dispersal pattern. Although Black-throated tits (Aegithalos concinnus) are socially monogamous and cooperatively breeding birds, limited observational data suggested that males may have the ability of long-distance dispersal. We have previously detected three highly supported mitochondrial populations within two subspecies of Black-throated tits (A. c. concinnus and A. c. talifuensis). Here, we used several genetic markers with different inheritance patterns to gain insights about their phylogeographic history. Phylogenetic and individual-based Bayesian analysis showed weak geographical structure amongst nuclear sequences (autosomal and Z-chromosomal loci). Coalescent analysis revealed high levels of gene flow among mitochondrial populations, even between allopatric populations. These results strongly suggested that male-biased gene flow was responsible for the discordant cytonuclear phylogeographic patterns. Consistent with expectation on the genetic consequence of long-distance male dispersal, mantel tests revealed a significant pattern of isolation by distance for mitochondrial sequences, but failed to provide a similar pattern for nuclear genes within a continuous population; female Black-throated tits showed a stronger but not significantly different relationship of isolation by distance than males when using mitochondrial DNA alone. We discussed the contribution of male juveniles with delayed dispersal to the non-significantly different IBD patterns between sexes. Our results using multilocus genetic data revealed aspects of the complex evolutionary history of Black-throated tits and the important role of long-distance male dispersal in the population structuring.

  6. The estimation of genetic distance and discriminant variables on breed of duck (Alabio, Bali, Khaki Campbell, Mojosari and Pegagan by morphological analysis

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    B Brahmantiyo

    2003-03-01

    Full Text Available A study on morphological body conformation of Alabio, Bali, Khaki Campbell, Mojosari and Pegagan ducks was carried out to determine the genetic distance and discriminant variables. This research was held in Research Institute for Animal Production, Ciawi, Bogor using 65 Alabio ducks, 40 Bali ducks, 36 Khaki Campbell ducks, 60 Mojosari ducks and 30 Pegagan ducks. Seven different body parts were measured, they were the length of femur, tibia, tarsometatarsus, the circumference of tarsometatarsus, the length of third digits, wing and maxilla. General Linear Models and simple discriminant analysis were used in this observation (SAS package program. Male and female Pegagan ducks had morphological size bigger than Alabio, Bali, Khaki Campbell and Mojosari ducks. Khaki Campbell ducks were mixed with Bali ducks (47.22% and Pegagan ducks from isolated location in South Sumatera were lightly mixed with Alabio and Bali. Mahalanobis genetic distance showed that Bali and Khaki Campbell ducks, also, Alabio and Mojosari ducks had similarity, with genetic distance of 1.420 and 1.548, respectively. Results from canonical analysis showed that the most discriminant variables were obtained from the length of femur, tibia and third digits.

  7. Information-theoretic indices and an approximate significance test for testing the molecular clock hypothesis with genetic distances.

    Science.gov (United States)

    Xia, Xuhua

    2009-09-01

    Distance-based phylogenetic methods are widely used in biomedical research. However, distance-based dating of speciation events and the test of the molecular clock hypothesis are relatively underdeveloped. Here I develop an approximate test of the molecular clock hypothesis for distance-based trees, as well as information-theoretic indices that have been used frequently in model selection, for use with distance matrices. The results are in good agreement with the conventional sequence-based likelihood ratio test. Among the information-theoretic indices, AICu is the most consistent with the sequence-based likelihood ratio test. The confidence in model selection by the indices can be evaluated by bootstrapping. I illustrate the usage of the indices and the approximate significance test with both empirical and simulated sequences. The tests show that distance matrices from protein gel electrophoresis and from genome rearrangement events do not violate the molecular clock hypothesis, and that the evolution of the third codon position conforms to the molecular clock hypothesis better than the second codon position in vertebrate mitochondrial genes. I outlined evolutionary distances that are appropriate for phylogenetic reconstruction and dating.

  8. Distance learning training in genetics and genomics testing for Italian health professionals: results of a pre and post-test evaluation

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    Maria Benedetta Michelazzo

    2015-09-01

    Full Text Available BackgroundProgressive advances in technologies for DNA sequencing and decreasing costs are allowing an easier diffusion of genetic and genomic tests. Physicians’ knowledge and confidence on the topic is often low and not suitable for manage this challenge. Tailored educational programs are required to reach a more and more appropriate use of genetic technologies.MethodsA distance learning course has been created by experts from different Italian medical associations with the support of the Italian Ministry of Health. The course was directed to professional figures involved in prescription and interpretation of genetic tests. A pretest-post-test study design was used to assess knowledge improvement. We analyzed the proportion of correct answers for each question pre and post-test, as well as the mean score difference stratified by gender, age, professional status and medical specialty.ResultsWe reported an improvement in the proportion of correct answers for 12 over 15 questions of the test. The overall mean score to the questions significantly increased in the post-test, from 9.44 to 12.49 (p-value < 0.0001. In the stratified analysis we reported an improvement in the knowledge of all the groups except for geneticists; the pre-course mean score of this group was already very high and did not improve significantly.ConclusionDistance learning is effective in improving the level of genetic knowledge. In the future, it will be useful to analyze which specialists have more advantage from genetic education, in order to plan more tailored education for medical professionals.

  9. Effect of distance and depth on soil microbial biomass, N mineralization and genetic diversity of Rhizobia under Acacia senegal Tree

    Energy Technology Data Exchange (ETDEWEB)

    Fall, D.; Faye, A.; Sall, S. N.; Diouf, D.

    2009-07-01

    The relations between plants and soil biota involve positive and negative feedbacks between soil organisms, their chemical environment, and plants. Then, the characterization of microbial community functioning and their diversity are important to understand these linkages. An experiment was conducted in a field system for two years (2005 and 2006) to investigate the effect of distance from tree stem on soil microbial biomass, N mineral content and the diversity of rhizobia associated to Acacia senegal. (Author)

  10. Relationship Between F1, F2 Hybrid Yield, Heterosis and Genetic Distance Measured by Molecular Markers and Parent Performance in Cotton

    Institute of Scientific and Technical Information of China (English)

    WU Yao-ting; ZHANG Tian-zhen; ZHU Xie-fei; WANG Guang-ming

    2002-01-01

    Genetic distance among 36 cotton cultivars measured by molecular markers of RAPDs, ISSRs,and SSRs was from 0.0701 to 0.4255 with the mean of 0.2844, and from 2.18 to 12.60 with the mean of 7.04 based on the genotype performance in two-year field experiments, which has a significant positive correlation (r = 0.3350). The correlative coefficients for boll number per plant, boll weight, yield per plant, lint percent and lint yield per plant were 0. 8035,0. 8877,0. 7135,0. 9640 and 0. 8956 between F1 and F2 hybrid performance assessed by three-environment field experiments, respectively. The mean of F1 and F2 hybrid heterosis of yield per plant and lint yield per plant were 13.62%, 16.31%, 7.90% and 9.02%, and the correlative coefficients between them were 0.3689 and 0.3787, respectively. The correlation between the genetic distance and heterosis was low, and influenced directly by the selected parents.

  11. Genotyping-by-sequencing approach indicates geographic distance as the main factor affecting genetic structure and gene flow in Brazilian populations of Grapholita molesta (Lepidoptera, Tortricidae).

    Science.gov (United States)

    Silva-Brandão, Karina Lucas; Silva, Oscar Arnaldo Batista Neto E; Brandão, Marcelo Mendes; Omoto, Celso; Sperling, Felix A H

    2015-06-01

    The oriental fruit moth Grapholita molesta is one of the major pests of stone and pome fruit species in Brazil. Here, we applied 1226 SNPs obtained by genotyping-by-sequencing to test whether host species associations or other factors such as geographic distance structured populations of this pest. Populations from the main areas of occurrence of G. molesta were sampled principally from peach and apple orchards. Three main clusters were recovered by neighbor-joining analysis, all defined by geographic proximity between sampling localities. Overall genetic structure inferred by a nonhierarchical amova resulted in a significant ΦST value = 0.19109. Here, we demonstrate for the first time that SNPs gathered by genotyping-by-sequencing can be used to infer genetic structure of a pest insect in Brazil; moreover, our results indicate that those markers are very informative even over a restricted geographic scale. We also demonstrate that host plant association has little effect on genetic structure among Brazilian populations of G. molesta; on the other hand, reduced gene flow promoted by geographic isolation has a stronger impact on population differentiation.

  12. Testing DNA barcode performance in 1000 species of European lepidoptera: large geographic distances have small genetic impacts.

    Science.gov (United States)

    Huemer, Peter; Mutanen, Marko; Sefc, Kristina M; Hebert, Paul D N

    2014-01-01

    This study examines the performance of DNA barcodes (mt cytochrome c oxidase 1 gene) in the identification of 1004 species of Lepidoptera shared by two localities (Finland, Austria) that are 1600 km apart. Maximum intraspecific distances for the pooled data were less than 2% for 880 species (87.6%), while deeper divergence was detected in 124 species. Despite such variation, the overall DNA barcode library possessed diagnostic COI sequences for 98.8% of the taxa. Because a reference library based on Finnish specimens was highly effective in identifying specimens from Austria, we conclude that barcode libraries based on regional sampling can often be effective for a much larger area. Moreover, dispersal ability (poor, good) and distribution patterns (disjunct, fragmented, continuous, migratory) had little impact on levels of intraspecific geographic divergence. Furthermore, the present study revealed that, despite the intensity of past taxonomic work on European Lepidoptera, nearly 20% of the species shared by Austria and Finland require further work to clarify their status. Particularly discordant BIN (Barcode Index Number) cases should be checked to ascertain possible explanatory factors such as incorrect taxonomy, hybridization, introgression, and Wolbachia infections.

  13. Karakterisasi Morfometrik dan Jarak Genetik Rumpun-Rumpun Kelinci di Jawa Barat (MORPHOMETRIC CHARACTERIZATION AND GENETIC DISTANCE OF RABBIT BREEDS IN WEST JAVA

    Directory of Open Access Journals (Sweden)

    Rudi Dedi Iskandar

    2017-01-01

    Full Text Available The objectives of this study were to assess morphometric characteristics, breeds relationship andvariables that distinguished among breeds of rabbits raised in West Java. This research used 419 rabbitsconsisted of Angora (AG, Dutch (DT, Flemish Giant (FG, Lop (LP, Netherland Dwarf (ND, Composite(PX, Rex (RX, Satin (ST, Reza (XA and New Zealand White (ZW. Head length (PK, head width (LK, earlength (PTL, ear width (LTL, chest width (LD, chest depth (DD, chest circumference (LKD, body length(PB , hips width (LP, length of the scapula bone (PS, humerus length (PH, radius-ulna length (PRU,femur length (PF and tibia length (PT were observed. Data were analyzed with analysis of variance,discriminant and canonical analysis using SAS program ver. 9.1.3 and MEGA5 program to get theconstruction of phenogram tree. FG and ST rabbits were generally larger in size and shape than the otherrabbits breeds, while ND rabbit had the smallest morphological size than other rabbits breeds, except forLK, LD and DD. Results of discriminant analysis showed that LP, RX, ND and XA had a high similarityvalue, otherwise DT, FG, ST, PX, AG and ZW had no the value. The closest genetic distance matrix valueindicated by PX-ZW breeds (1,53 and the farthest genetic distance indicated by FG-ND breeds (6,62.Phenogram tree construction showed that the breeds rabbits divided into five clusters, namely cluster ND,DT; ST clusters; FG cluster; cluster LP, PX, ZW and cluster AG, XA, RX. Phenotypic size that had stronginfluence on the differentiation of rabbit breeds were PTL, LTL, PRU, PH and PF on the canonical 1 alsoPT and PS on canonical 2.

  14. Influence of long-distance seed dispersal on the genetic diversity of seed rain in fragmented Pinus densiflora populations relative to pollen-mediated gene flow.

    Science.gov (United States)

    Ozawa, Hajime; Watanabe, Atsushi; Uchiyama, Kentaro; Saito, Yoko; Ide, Yuji

    2013-01-01

    Long-distance dispersal (LDD) of seeds has a critical impact on species survival in patchy landscapes. However, relative to pollen dispersal, empirical data on how seed LDD affects genetic diversity in fragmented populations have been poorly reported. Thus, we attempted to indirectly evaluate the influence of seed LDD by estimating maternal and paternal inbreeding in the seed rain of fragmented 8 Pinus densiflora populations. In total, the sample size was 458 seeds and 306 adult trees. Inbreeding was estimated by common parentage analysis to evaluate gene flow within populations and by sibship reconstruction analysis to estimate gene flow within and among populations. In the parentage analysis, the observed probability that sampled seeds had the same parents within populations was significantly larger than the expected probability in many populations. This result suggested that gene dispersal was limited to within populations. In the sibship reconstruction, many donors both within and among populations appeared to contribute to sampled seeds. Significant differences in sibling ratios were not detected between paternity and maternity. These results suggested that seed-mediated gene flow and pollen-mediated gene flow from outside population contributed some extent to high genetic diversity of the seed rain (H E > 0.854). We emphasize that pine seeds may have excellent potential for gene exchange within and among populations.

  15. Genetic distances in soybean based on RAPD markers Distâncias genéticas em soja com base em marcadores RAPD

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    RONAN XAVIER CORRÊA

    1999-01-01

    Full Text Available Four methods were applied to determine pairwise genetic distances among five soybean genotypes which are potential genitors for a mapping population. Additionally, individual plants from the most divergent pair of genotypes were evaluated by the RAPD technique to determine their degree of homozygosity. Genetic distances based on RAPD data were calculated by the modified Rogers' distance, and also by the following arithmetical complements of similarity: simple match, Nei and Li, and Gower. These genetic distances were similar, presenting a correlation coefficient ranging from 0.99 to 1.00. In all four methods lines UFV 91-717 and Ichigowase were the most divergent ones (4.53 to 21.43%. DNA samples from five plants from each of the two most divergent genotypes were amplified with 28 different primers. Among the amplified products, only five were polymorphic in each group (2.10%, demonstrating their high intragroup degree of homozygosity. These homozygosity were maintained when DNA samples from 12 plants from each of the two most divergent genotypes were amplified. These parameters were extremely useful for the confirmation of the chosen pair of genitors to generate a mapping population.Aplicaram-se quatro métodos para determinar as distâncias genéticas entre cinco cultivares de soja, que são genitores potenciais para uma população de mapeamento genético. Adicionalmente, o grau de homozigose do par de genótipos mais divergente foi avaliado por meio da técnica de RAPD. Calcularam-se as distâncias genéticas fundadas em dados obtidos pela técnica de RAPD pela distância modificada de Rogers e pelos seguintes complementos aritméticos de similaridade: distância simples; Nei e Li, e Gower. As distâncias genéticas foram similares, apresentando valores de coeficiente de correlação de 0,99 a 1,00. Nos quatro métodos, as linhagens UFV 91-717 e Ichigowase foram as mais divergentes (4,53 to 21,43%. Amostras de DNA de cinco plantas de cada

  16. Simple Genetic Distance-Optimized Field Deployments for Clonal Seed Orchards Based on Microsatellite Markers: As a Case of Chinese Pine Seed Orchard.

    Directory of Open Access Journals (Sweden)

    Huwei Yuan

    Full Text Available Chinese pine seed orchards are in a period of transition from first-generation to advanced-generations. How to effectively select populations for second-generation seed orchards and significantly increase genetic gain through rational deployment have become major issues. In this study, we examined open- and control-pollinated progeny of the first-generation Chinese pine seed orchards in Zhengning (Gansu Province, China and Xixian (Shanxi Province, China to address issues related to phenotypic selection for high volume growth, genetic diversity analysis and genetic distance-based phylogenetic analysis of the selections by simple sequence repeats (SSRs, and phylogenetic relationship-based field deployment for advanced-generation orchards. In total, 40, 28, 20, and 13 superior individuals were selected from the large-scale no-pedigree open-pollinated progeny of Zhengning (ZN-NP, open-pollinated families of Zhengning (ZN-OP, open-pollinated families of Xixian (XX-OP, and control-pollinated families of Xixian, with mean volume dominance ratios of 0.83, 0.15, 0.25, and 0.20, respectively. Phylogenetic relationship analysis of the ZN-NP and XX-OP populations showed that the 40 superior individuals in the ZN-NP selected population belonged to 23 families and could be further divided into five phylogenetic groups, and that families in the same group were closely related. Similarly, 20 families in the XX-OP population were related to varying degrees. Based on these results, we found that second-generation Chinese pine seed orchards in Zhengning and Xixian should adopt a grouped, unbalanced, complete, fixed block design and an unbalanced, incomplete, fixed block design, respectively. This study will provide practical references for applying molecular markers to establishing advanced-generation seed orchards.

  17. Genetics

    Science.gov (United States)

    ... Inheritance; Heterozygous; Inheritance patterns; Heredity and disease; Heritable; Genetic markers ... The chromosomes are made up of strands of genetic information called DNA. Each chromosome contains sections of ...

  18. Real-Time Pathogen Detection in the Era of Whole-Genome Sequencing and Big Data: Comparison of k-mer and Site-Based Methods for Inferring the Genetic Distances among Tens of Thousands of Salmonella Samples.

    Science.gov (United States)

    Pettengill, James B; Pightling, Arthur W; Baugher, Joseph D; Rand, Hugh; Strain, Errol

    2016-01-01

    The adoption of whole-genome sequencing within the public health realm for molecular characterization of bacterial pathogens has been followed by an increased emphasis on real-time detection of emerging outbreaks (e.g., food-borne Salmonellosis). In turn, large databases of whole-genome sequence data are being populated. These databases currently contain tens of thousands of samples and are expected to grow to hundreds of thousands within a few years. For these databases to be of optimal use one must be able to quickly interrogate them to accurately determine the genetic distances among a set of samples. Being able to do so is challenging due to both biological (evolutionary diverse samples) and computational (petabytes of sequence data) issues. We evaluated seven measures of genetic distance, which were estimated from either k-mer profiles (Jaccard, Euclidean, Manhattan, Mash Jaccard, and Mash distances) or nucleotide sites (NUCmer and an extended multi-locus sequence typing (MLST) scheme). When analyzing empirical data (whole-genome sequence data from 18,997 Salmonella isolates) there are features (e.g., genomic, assembly, and contamination) that cause distances inferred from k-mer profiles, which treat absent data as informative, to fail to accurately capture the distance between samples when compared to distances inferred from differences in nucleotide sites. Thus, site-based distances, like NUCmer and extended MLST, are superior in performance, but accessing the computing resources necessary to perform them may be challenging when analyzing large databases.

  19. Distance Learning

    Science.gov (United States)

    1997-12-01

    A study reviewing the existing Army Distance Learning Plan (ADLP) and current Distance Learning practices, with a focus on the Army’s training and...educational challenges and the benefits of applying Distance Learning techniques. The ASB study panel makes six specific recommendations, the most

  20. Isolation by distance, web service

    OpenAIRE

    Bohonak Andrew J; Jensen Jeffrey L; Kelley Scott T

    2005-01-01

    Abstract Background The population genetic pattern known as "isolation by distance" results from spatially limited gene flow and is a commonly observed phenomenon in natural populations. However, few software programs exist for estimating the degree of isolation by distance among populations, and they tend not to be user-friendly. Results We have created Isolation by Distance Web Service (IBDWS) a user-friendly web interface for determining patterns of isolation by distance. Using this site, ...

  1. Information Distance

    CERN Document Server

    Bennett, Charles H; Li, Ming; Vitanyi, Paul M B; Zurek, Wojciech H

    2010-01-01

    While Kolmogorov complexity is the accepted absolute measure of information content in an individual finite object, a similarly absolute notion is needed for the information distance between two individual objects, for example, two pictures. We give several natural definitions of a universal information metric, based on length of shortest programs for either ordinary computations or reversible (dissipationless) computations. It turns out that these definitions are equivalent up to an additive logarithmic term. We show that the information distance is a universal cognitive similarity distance. We investigate the maximal correlation of the shortest programs involved, the maximal uncorrelation of programs (a generalization of the Slepian-Wolf theorem of classical information theory), and the density properties of the discrete metric spaces induced by the information distances. A related distance measures the amount of nonreversibility of a computation. Using the physical theory of reversible computation, we give...

  2. Genetics

    DEFF Research Database (Denmark)

    Christensen, Kaare; McGue, Matt

    2016-01-01

    The sequenced genomes of individuals aged ≥80 years, who were highly educated, self-referred volunteers and with no self-reported chronic diseases were compared to young controls. In these data, healthy ageing is a distinct phenotype from exceptional longevity and genetic factors that protect...

  3. [A simple method to correct genetic distance between linked genes and a correction of calculating data in tetrad analysis in Neurospora crassa].

    Science.gov (United States)

    Li, You-Yong; Zhao, Yuan-Zeng

    2003-05-01

    The present paper is dealing with a simple method to correct the distance of linked genes in tetrad analysis in Neurospora crassa. It is suggested that the data of 4-thread double crossing over should be added in two single crossing over respectively in centromere maping when calculating crossover value of the two genes locating across the centromere.

  4. 玉米自交系籽粒的遗传距离与其近红外光谱距离和品种鉴别模型性能的关系研究%A Study of the Relationship Among Genetic Distances,NIR Spectra Distances,and NIR-Based Identification Model Performance of the Seeds of Maize Iinbred Lines

    Institute of Scientific and Technical Information of China (English)

    刘旭; 黄华军; 安冬; 贾仕强; 王春英; 刘哲; 顾建成; 翟伟; 李绍明; 张晓东; 朱德海

    2015-01-01

    从玉米自交系种子的遗传距离、近红外光谱距离、品种鉴别模型性能三方面进行分析,探索三者间的关系。采用三组(共15对)遗传关系远近不同的玉米自交系种子作为实验材料,通过简单重复序列(simple sequence repeats,SSR)标记计算自交系种子间的遗传距离;种子的近红外光谱经预处理后降维到主成分分析(principal component analysis,PCA)空间中,计算各个自交系种子样本中心点之间的欧氏距离,作为对应的近红外光谱距离;使用仿生模式识别方法建立鉴别模型,用模型的鉴别正确率评价模型的性能。分析结果表明,自交系种子间遗传距离与近红外光谱距离相关性为0.9868,与模型鉴别正确率的相关性为0.9110,相关性显著。说明近红外光谱可以反映出玉米自交系种子之间的遗传关系,遗传关系的远近影响品种鉴别模型的性能,遗传距离越小,近红外光谱距离越小,模型鉴别能力也越差。实际应用中有望利用近红外光谱技术分析玉米自交系的遗传关系,对遗传育种、品种识别、纯度分选等具有重要意义;且建立品种鉴别模型时,应充分考虑遗传关系较近的玉米自交系对模型性能的影响。%This paper explored the relationship among genetic distances,NIR spectra distances and NIR-based identification model performance of the seeds of maize inbred lines.Using 3 groups (total 15 pairs)of maize inbred lines whose genetic dis-taches are different as experimental materials,we calculates the genetic distance between these seeds with SSR markers and uses Euclidean distance between distributed center points of maize NIR spectrum in the PCA space as the distances of NIR spectrum. BPR method is used to build identification model of inbred lines andthe identification accuracy is used as a measure of model iden-tification performance.The results showed that the

  5. Genotyping-by-sequencing approach indicates geographic distance as the main factor affecting genetic structure and gene flow in Brazilian populations of Grapholita molesta (Lepidoptera, Tortricidae)

    OpenAIRE

    Silva-Brandão, Karina Lucas; Oscar Arnaldo Batista Neto E Silva; Brandão, Marcelo Mendes; Omoto, Celso; Sperling, Felix A. H.

    2015-01-01

    The oriental fruit moth Grapholita molesta is one of the major pests of stone and pome fruit species in Brazil. Here, we applied 1226 SNPs obtained by genotyping-by-sequencing to test whether host species associations or other factors such as geographic distance structured populations of this pest. Populations from the main areas of occurrence of G. molesta were sampled principally from peach and apple orchards. Three main clusters were recovered by neighbor-joining analysis, all defined by g...

  6. High genetic diversity of Vibrio cholerae in the European lake Neusiedler See is associated with intensive recombination in the reed habitat and the long-distance transfer of strains.

    Science.gov (United States)

    Pretzer, Carina; Druzhinina, Irina S; Amaro, Carmen; Benediktsdóttir, Eva; Hedenström, Ingela; Hervio-Heath, Dominique; Huhulescu, Steliana; Schets, Franciska M; Farnleitner, Andreas H; Kirschner, Alexander K T

    2017-01-01

    Coastal marine Vibrio cholerae populations usually exhibit high genetic diversity. To assess the genetic diversity of abundant V. cholerae non-O1/non-O139 populations in the Central European lake Neusiedler See, we performed a phylogenetic analysis based on recA, toxR, gyrB and pyrH loci sequenced for 472 strains. The strains were isolated from three ecologically different habitats in a lake that is a hot-spot of migrating birds and an important bathing water. We also analyzed 76 environmental and human V. cholerae non-O1/non-O139 isolates from Austria and other European countries and added sequences of seven genome-sequenced strains. Phylogenetic analysis showed that the lake supports a unique endemic diversity of V. cholerae that is particularly rich in the reed stand. Phylogenetic trees revealed that many V. cholerae isolates from European countries were genetically related to the strains present in the lake belonging to statistically supported monophyletic clades. We hypothesize that the observed phenomena can be explained by the high degree of genetic recombination that is particularly intensive in the reed stand, acting along with the long distance transfer of strains most probably via birds and/or humans. Thus, the Neusiedler See may serve as a bioreactor for the appearance of new strains with new (pathogenic) properties. © 2016 The Authors. Environmental Microbiology published by Society for Applied Microbiology and John Wiley & Sons Ltd.

  7. Pendugaan Jarak Genetik Kelinci (Hyla, Hycole, Hycolex NZW, Rex, dan Satin Melalui Analisis Morfometrik (ESTIMATION OF RABBIT GENETIC DISTANCE (HYLA, HYCOLE, HYCOLEXNZW, NZW, REX AND SATIN THROUGH MORPHOMETRIC ANALYSIS

    Directory of Open Access Journals (Sweden)

    Bram Brahmantiyo

    2016-07-01

    Full Text Available The observation on morphological body conformation of Hyla (CC, Hycole (FF, HycolexNZW (FN,New Zealand White (NN, Rex (RR, and Satin (SS were carried out to determine estimation of mahalanobisgenetic distance. This research was held in Ciawi Bogor Livestock Research Institute (Balai PenelitianTernak Ciawi, Bogor which 95 head of male rabbits were used. Fourteen different body parts measuredwere head (length, width, and height, ear (length and width, chest (depth, girth, and width, scapulalength, ulna length, femur length, tibia length, body length, and hips wide. CC, FF, FN, and NN rabbits hadbigger morphological size than RR and SS rabbits. Mahalanobis genetic distance showed that geneticdistance of FF and SS rabbits was the biggest (4.36. Result of canonical analysis showed that the mostdiscriminate variables were obtained by head width, ear length, ulna length, tibia length, body length, andhips wide for first canonical. The conclusion of this study that Rex and Satin rabbits were have differentgenetic distance with Hyla, Hycole, HycolexNZW and NZW rabbits.

  8. Superclone Expansion, Long-Distance Clonal Dispersal and Local Genetic Structuring in the Coral Pocillopora damicornis Type β in Reunion Island, South Western Indian Ocean

    Science.gov (United States)

    Gélin, Pauline; Fauvelot, Cécile; Mehn, Vincent; Bureau, Sophie; Rouzé, Héloïse; Magalon, Hélène

    2017-01-01

    The scleractinian coral Pocillopora damicornis type β is known to present a mixed reproduction mode: through sexual reproduction, new genotypes are created, while asexual reproduction insures their propagation. In order to investigate the relative proportion of each reproduction mode in P. damicornis type β populations from Reunion Island, Indian Ocean, clonal propagation along the west coast was assessed through four sampling sites with increasing geographical distance between sites. Coral colonies were sampled either exhaustively, randomly or haphazardly within each site, and genotypic diversity was assessed using 13 microsatellite loci over a total of 510 P. damicornis type β determined a posteriori from their mtDNA haplotype (a 840 bp sequenced fragment of the Open Reading Frame). Overall, 47% of all the sampled colonies presented the same multi-locus genotype (MLG), a superclone, suggesting that asexual propagation is extremely important in Reunion Island. Within each site, numerous MLGs were shared by several colonies, suggesting local clonal propagation through fragmentation. Moreover, some of these MLGs were found to be shared among several sites located 40 km apart. While asexual reproduction by fragmentation seems unlikely over long distances, our results suggest a production of parthenogenetic larvae. Despite shared MLGs, two differentiated clusters were enclosed among populations of the west coast of Reunion Island, revealing the necessity to set up appropriate managing strategies at a local scale. PMID:28068406

  9. 改进遗传算法在输气管道运行优化中的应用%Application of Improved Genetic Algorithm in Optimal Operation of Long-distance Natural Gas Pipelines

    Institute of Scientific and Technical Information of China (English)

    蒋毅; 陈次昌; 陈芬

    2009-01-01

    Aiming at the issues existed in conventional genetic algorithm(GA)widely used in operation optimization of natural gas pipelines,improvement is made combined with operational characteristics of the pipelines.Optimized calculation with the improved GA is carried out to actual gas pipeline and results show that the improved GA is better than dynamic programming method and conventional genetic algorithm,which demonstrates a practical value in the process of operational optimization of long distance gas pipelines.%针对在天然气长输管道运行优化中广泛使用的传统遗传算法存在的诸多问题,结合天然气长输管道的运行特点,对传统遗传算法加以改进.使用改进后的遗传算法对管道运行优化的计算结果表明,改进遗传算法优于动态规划算法和传统遗传算法,在天然气长输管道的运行优化过程中具有实用价值.

  10. Isolation by distance, web service

    Directory of Open Access Journals (Sweden)

    Bohonak Andrew J

    2005-03-01

    Full Text Available Abstract Background The population genetic pattern known as "isolation by distance" results from spatially limited gene flow and is a commonly observed phenomenon in natural populations. However, few software programs exist for estimating the degree of isolation by distance among populations, and they tend not to be user-friendly. Results We have created Isolation by Distance Web Service (IBDWS a user-friendly web interface for determining patterns of isolation by distance. Using this site, population geneticists can perform a variety of powerful statistical tests including Mantel tests, Reduced Major Axis (RMA regression analysis, as well as calculate FST between all pairs of populations and perform basic summary statistics (e.g., heterozygosity. All statistical results, including publication-quality scatter plots in Postscript format, are returned rapidly to the user and can be easily downloaded. Conclusion IBDWS population genetics analysis software is hosted at http://phage.sdsu.edu/~jensen/ and documentation is available at http://www.bio.sdsu.edu/pub/andy/IBD.html. The source code has been made available on Source Forge at http://sourceforge.net/projects/ibdws/.

  11. Encyclopedia of distances

    CERN Document Server

    Deza, Michel Marie

    2016-01-01

    This 4th edition of the leading reference volume on distance metrics is characterized by updated and rewritten sections on some items suggested by experts and readers, as well a general streamlining of content and the addition of essential new topics. Though the structure remains unchanged, the new edition also explores recent advances in the use of distances and metrics for e.g. generalized distances, probability theory, graph theory, coding theory, data analysis. New topics in the purely mathematical sections include e.g. the Vitanyi multiset-metric, algebraic point-conic distance, triangular ratio metric, Rossi-Hamming metric, Taneja distance, spectral semimetric between graphs, channel metrization, and Maryland bridge distance. The multidisciplinary sections have also been supplemented with new topics, including: dynamic time wrapping distance, memory distance, allometry, atmospheric depth, elliptic orbit distance, VLBI distance measurements, the astronomical system of units, and walkability distance. Lea...

  12. Optimal Selection of Nonuniform Code of Radar Based on Euclidean Distance-adaptive Genetic Algorithm%基于欧式距离约束自适应遗传算法的参差码搜索

    Institute of Scientific and Technical Information of China (English)

    张明博; 罗丰

    2009-01-01

    提出了一种基于欧式距离约束的自适应遗传算法(Euclidean distance-Adaptive Genetic Algorithm,EAGA),该算法将欧式距离引入自适应交叉概率,使交叉概率随适应度和个体之间的相似度自适应变化,更好地增强种群的多样性,保存优良个体;为了防止EAGA在优化过程中出现退化现象,通过融合按照一定规则产生的新个体对算法进行了改进.采用EAGA选择最优参差比,使滤波器的零点尽可能的浅,在有效抑制杂波的同时避免目标丢失.同标准遗传算法相比,EAGA表现出了较好的搜索性能.

  13. Distance Education Council.

    Science.gov (United States)

    Indira Gandhi National Open University, New Delhi (India). Distance Education Council.

    Since its inception in India in 1962, distance education has grown in popularity. The Distance Education Council (DEC) directs distance learning within India's higher education system. The DEC's promotion, coordination, and maintenance of standards for distance education are its three major roles. Its initiatives include grants, support for…

  14. Training for Distance Teaching through Distance Learning.

    Science.gov (United States)

    Cadorath, Jill; Harris, Simon; Encinas, Fatima

    2002-01-01

    Describes a mixed-mode bachelor degree course in English language teaching at the Universidad Autonoma de Puebla (Mexico) that was designed to help practicing teachers write appropriate distance education materials by giving them the experience of being distance students. Includes a course outline and results of a course evaluation. (Author/LRW)

  15. Encyclopedia of distances

    CERN Document Server

    Deza, Michel Marie

    2014-01-01

    This updated and revised third edition of the leading reference volume on distance metrics includes new items from very active research areas in the use of distances and metrics such as geometry, graph theory, probability theory and analysis. Among the new topics included are, for example, polyhedral metric space, nearness matrix problems, distances between belief assignments, distance-related animal settings, diamond-cutting distances, natural units of length, Heidegger’s de-severance distance, and brain distances. The publication of this volume coincides with intensifying research efforts into metric spaces and especially distance design for applications. Accurate metrics have become a crucial goal in computational biology, image analysis, speech recognition and information retrieval. Leaving aside the practical questions that arise during the selection of a ‘good’ distance function, this work focuses on providing the research community with an invaluable comprehensive listing of the main available di...

  16. Distances from Planetary Nebulae

    CERN Document Server

    Ciardullo, R

    2003-01-01

    The [O III] 5007 planetary nebula luminosity function (PNLF) occupies an important place on the extragalactic distance ladder. Since it is the only method that is applicable to all the large galaxies of the Local Supercluster, it is uniquely useful for cross-checking results and linking the Population I and Population II distance scales. We review the physics underlying the method, demonstrate its precision, and illustrate its value by comparing its distances to distances obtained from Cepheids and the Surface Brightness Fluctuation (SBF) method. We use the Cepheid and PNLF distances to 13 galaxies to show that the metallicity dependence of the PNLF cutoff is in excellent agreement with that predicted from theory, and that no additional systematic corrections are needed for either method. However, when we compare the Cepheid-calibrated PNLF distance scale with the Cepheid-calibrated SBF distance scale, we find a significant offset: although the relative distances of both methods are in excellent agreement, th...

  17. A generalized evidence distance

    Institute of Scientific and Technical Information of China (English)

    Hongming Mo; Xi Lu; Yong Deng

    2016-01-01

    How to efficiently measure the distance between two basic probability assignments (BPAs) is an open issue. In this paper, a new method to measure the distance between two BPAs is proposed, based on two existing measures of evidence distance. The new proposed method is comprehen-sive and generalized. Numerical examples are used to ilus-trate the effectiveness of the proposed method.

  18. Tourists consuming distance

    DEFF Research Database (Denmark)

    Larsen, Gunvor Riber

    The environmental impact of tourism mobility is linked to the distances travelled in order to reach a holiday destination, and with tourists travelling more and further than previously, an understanding of how the tourists view the distance they travel across becomes relevant. Based on interviews...... contribute to an understanding of how it is possible to change tourism travel behaviour towards becoming more sustainable. How tourists 'consume distance' is discussed, from the practical level of actually driving the car or sitting in the air plane, to the symbolic consumption of distance that occurs when...... travelling on holiday becomes part of a lifestyle and a social positioning game. Further, different types of tourist distance consumers are identified, ranging from the reluctant to the deliberate and nonchalant distance consumers, who display very differing attitudes towards the distance they all travel...

  19. Learning string edit distance

    CERN Document Server

    Ristad, E S; Ristad, Eric Sven; Yianilos, Peter N.

    1996-01-01

    In many applications, it is necessary to determine the similarity of two strings. A widely-used notion of string similarity is the edit distance: the minimum number of insertions, deletions, and substitutions required to transform one string into the other. In this report, we provide a stochastic model for string edit distance. Our stochastic model allows us to learn a string edit distance function from a corpus of examples. We illustrate the utility of our approach by applying it to the difficult problem of learning the pronunciation of words in conversational speech. In this application, we learn a string edit distance with one fourth the error rate of the untrained Levenshtein distance. Our approach is applicable to any string classification problem that may be solved using a similarity function against a database of labeled prototypes. Keywords: string edit distance, Levenshtein distance, stochastic transduction, syntactic pattern recognition, prototype dictionary, spelling correction, string correction, ...

  20. Interface Simulation Distances

    Directory of Open Access Journals (Sweden)

    Pavol Černý

    2012-10-01

    Full Text Available The classical (boolean notion of refinement for behavioral interfaces of system components is the alternating refinement preorder. In this paper, we define a distance for interfaces, called interface simulation distance. It makes the alternating refinement preorder quantitative by, intuitively, tolerating errors (while counting them in the alternating simulation game. We show that the interface simulation distance satisfies the triangle inequality, that the distance between two interfaces does not increase under parallel composition with a third interface, and that the distance between two interfaces can be bounded from above and below by distances between abstractions of the two interfaces. We illustrate the framework, and the properties of the distances under composition of interfaces, with two case studies.

  1. Keeping Your Distance

    Directory of Open Access Journals (Sweden)

    Glen Gatin

    2013-06-01

    Full Text Available This analysis began with inquiries into the substantive area of distance education using the classic grounded theory method. Analysis revealed a pattern of problemsolving behavior, from which the theory Keeping Your Distance emerged. The theory is an integrated set of concepts referring to the conscious and unconscious strategiesthat people use to regulate distance, physical and representative, in their everyday lives. Strategies are used to control physical, emotional, and psychological realities and to conserve personal energy in interactions with individuals and/or institutions.For all social interactions, people use a personalized algorithm of engagement that mitigates conditions and consequences and preserves optimal distance. Keeping Your Distance provides a theoretical starting point for considerations of the changing notions of distance. In part, these changes have been brought about bydevelopments in the fields of Information and Communication Technology (ICT and online social networking.

  2. Numerical distance protection

    CERN Document Server

    Ziegler, Gerhard

    2011-01-01

    Distance protection provides the basis for network protection in transmission systems and meshed distribution systems. This book covers the fundamentals of distance protection and the special features of numerical technology. The emphasis is placed on the application of numerical distance relays in distribution and transmission systems.This book is aimed at students and engineers who wish to familiarise themselves with the subject of power system protection, as well as the experienced user, entering the area of numerical distance protection. Furthermore it serves as a reference guide for s

  3. Normalized information distance

    NARCIS (Netherlands)

    Vitányi, P.M.B.; Balbach, F.J.; Cilibrasi, R.L.; Li, M.; Emmert-Streib, F.; Dehmer, M.

    2009-01-01

    The normalized information distance is a universal distance measure for objects of all kinds. It is based on Kolmogorov complexity and thus uncomputable, but there are ways to utilize it. First, compression algorithms can be used to approximate the Kolmogorov complexity if the objects have a string

  4. Normalized information distance

    NARCIS (Netherlands)

    Vitányi, P.M.B.; Balbach, F.J.; Cilibrasi, R.L.; Li, M.

    2008-01-01

    The normalized information distance is a universal distance measure for objects of all kinds. It is based on Kolmogorov complexity and thus uncomputable, but there are ways to utilize it. First, compression algorithms can be used to approximate the Kolmogorov complexity if the objects have a string

  5. Incremental Distance Transforms (IDT)

    NARCIS (Netherlands)

    Schouten, Theo E.; van den Broek, Egon; Erçil, A.; Çetin, M.; Boyer, K.; Lee, S.-W.

    2010-01-01

    A new generic scheme for incremental implementations of distance transforms (DT) is presented: Incremental Distance Transforms (IDT). This scheme is applied on the cityblock, Chamfer, and three recent exact Euclidean DT (E2DT). A benchmark shows that for all five DT, the incremental implementation r

  6. ORDERED WEIGHTED DISTANCE MEASURE

    Institute of Scientific and Technical Information of China (English)

    Zeshui XU; Jian CHEN

    2008-01-01

    The aim of this paper is to develop an ordered weighted distance (OWD) measure, which is thegeneralization of some widely used distance measures, including the normalized Hamming distance, the normalized Euclidean distance, the normalized geometric distance, the max distance, the median distance and the min distance, etc. Moreover, the ordered weighted averaging operator, the generalized ordered weighted aggregation operator, the ordered weighted geometric operator, the averaging operator, the geometric mean operator, the ordered weighted square root operator, the square root operator, the max operator, the median operator and the min operator axe also the special cases of the OWD measure. Some methods depending on the input arguments are given to determine the weights associated with the OWD measure. The prominent characteristic of the OWD measure is that it can relieve (or intensify) the influence of unduly large or unduly small deviations on the aggregation results by assigning them low (or high) weights. This desirable characteristic makes the OWD measure very suitable to be used in many actual fields, including group decision making, medical diagnosis, data mining, and pattern recognition, etc. Finally, based on the OWD measure, we develop a group decision making approach, and illustrate it with a numerical example.

  7. Duty and Distance

    NARCIS (Netherlands)

    C. Binder (C.); C. Heilmann (Conrad)

    2017-01-01

    markdownabstractEver since the publication of Peter Singer’s article ‘‘Famine, Affluence, and Morality’’ has the question of whether the (geographical) distance to people in need affects our moral duties towards them been a hotly debated issue. Does geographical distance affect our moral duties?

  8. Biomechanics of Distance Running.

    Science.gov (United States)

    Cavanagh, Peter R., Ed.

    Contributions from researchers in the field of running mechanics are included in the 13 chapters of this book. The following topics are covered: (1) "The Mechanics of Distance Running: A Historical Perspective" (Peter Cavanagh); (2) "Stride Length in Distance Running: Velocity, Body Dimensions, and Added Mass Effects" (Peter Cavanagh, Rodger…

  9. Distance Learning Environment Demonstration.

    Science.gov (United States)

    1996-11-01

    The Distance Learning Environment Demonstration (DLED) was a comparative study of distributed multimedia computer-based training using low cost high...measurement. The DLED project provides baseline research in the effective use of distance learning and multimedia communications over a wide area ATM/SONET

  10. Duty and Distance

    NARCIS (Netherlands)

    C. Binder (C.); C. Heilmann (Conrad)

    2017-01-01

    markdownabstractEver since the publication of Peter Singer’s article ‘‘Famine, Affluence, and Morality’’ has the question of whether the (geographical) distance to people in need affects our moral duties towards them been a hotly debated issue. Does geographical distance affect our moral

  11. Estimating distances from parallaxes

    Science.gov (United States)

    Astraatmadja, Tri L.; Bailer-Jones, Coryn

    2017-01-01

    In astrometric surveys such as Gaia and LSST, parallaxes will be measured for about a billion stars, but zero distances will be measured. Distances must be inferred from the parallaxes, and the common inference practice is by inverting the parallax. This, however, is only appropriate when there is no noise present. As noise will always be present and most stars in future surveys will have non-negligible fractional parallax uncertainties, we must treat distance estimation as an inference problem. The usage of prior assumptions become unavoidable. In this talk I will present a method on how to infer distances using Bayesian inference. Three minimalists, isotropic priors are used, as well an anisotropic prior derived from the observability of stars in a Milky Way model. The performance of these priors are investigated using a simulated Gaia-like catalogue. Recent results of distance estimation using the parallaxes of 2 million Gaia DR1 stars will also be discussed.

  12. Normalized Information Distance

    CERN Document Server

    Vitanyi, Paul M B; Cilibrasi, Rudi L; Li, Ming

    2008-01-01

    The normalized information distance is a universal distance measure for objects of all kinds. It is based on Kolmogorov complexity and thus uncomputable, but there are ways to utilize it. First, compression algorithms can be used to approximate the Kolmogorov complexity if the objects have a string representation. Second, for names and abstract concepts, page count statistics from the World Wide Web can be used. These practical realizations of the normalized information distance can then be applied to machine learning tasks, expecially clustering, to perform feature-free and parameter-free data mining. This chapter discusses the theoretical foundations of the normalized information distance and both practical realizations. It presents numerous examples of successful real-world applications based on these distance measures, ranging from bioinformatics to music clustering to machine translation.

  13. Estimating distances from parallaxes

    CERN Document Server

    Bailer-Jones, C A L

    2015-01-01

    Astrometric surveys such as Gaia and LSST will measure parallaxes for hundreds of millions of stars. Yet they will not measure a single distance. Rather, a distance must be estimated from a parallax. In this didactic article, I show that doing this is not trivial once the fractional parallax error is larger than about 20%, which will be the case for about 80% of stars in the Gaia catalogue. Estimating distances is an inference problem in which the use of prior assumptions is unavoidable. I investigate the properties and performance of various priors and examine their implications. A supposed uninformative uniform prior in distance is shown to give very poor distance estimates (large bias and variance). Any prior with a sharp cut-off at some distance has similar problems. The choice of prior depends on the information one has available - and is willing to use - concerning, for example, the survey and the Galaxy. I demonstrate that a simple prior which decreases asymptotically to zero at infinite distance has g...

  14. MOTIVATION FOR DISTANCE EDUCATION

    Directory of Open Access Journals (Sweden)

    R zvan TEF NESCU

    2009-10-01

    Full Text Available Beginning with the 1980’s the new information, communication and computer based technologies stimulated the development of the distance education. In Romania the universities adapted rapidly to this type of learning that became an important financing source for most of them. In this article we approach the causes of attraction for the distance education. For this purpose we use an investigation we did on a group of students at Distance Education including interviews regarding their reasons for choosing this type of learning.

  15. Distance learning perspectives.

    Science.gov (United States)

    Pandza, Haris; Masic, Izet

    2013-01-01

    The development of modern technology and the Internet has enabled the explosive growth of distance learning. distance learning is a process that is increasingly present in the world. This is the field of education focused on educating students who are not physically present in the traditional classrooms or student's campus. described as a process where the source of information is separated from the students in space and time. If there are situations that require the physical presence of students, such as when a student is required to physically attend the exam, this is called a hybrid form of distance learning. This technology is increasingly used worldwide. The Internet has become the main communication channel for the development of distance learning.

  16. Learning Pullback HMM Distances.

    Science.gov (United States)

    Cuzzolin, Fabio; Sapienza, Michael

    2014-07-01

    Recent work in action recognition has exposed the limitations of methods which directly classify local features extracted from spatio-temporal video volumes. In opposition, encoding the actions' dynamics via generative dynamical models has a number of attractive features: however, using all-purpose distances for their classification does not necessarily deliver good results. We propose a general framework for learning distance functions for generative dynamical models, given a training set of labelled videos. The optimal distance function is selected among a family of pullback ones, induced by a parametrised automorphism of the space of models. We focus here on hidden Markov models and their model space, and design an appropriate automorphism there. Experimental results are presented which show how pullback learning greatly improves action recognition performances with respect to base distances.

  17. Presence at a distance.

    Science.gov (United States)

    Haddouk, Lise

    2015-01-01

    Nowadays in the context of the cyberculture, computer-mediated inter-subjective relationships are part of our everyday lives, in both the professional and personal spheres, and for all age groups. In the clinical field, many applications have been developed to facilitate the exchange of informations and mediate the relationship between patient and therapist. In psychology, more or less immersive technologies are used, to encourage the feeling of presence among the users, and to trigger certain psychological processes. In our research, we have explored the remote clinical interview through videoconferencing, with the development and utilisation of the iPSY platform, totally focused on this objective. In this context, we have considered the notion of intersubjectivity, despite the physical absence. This research is leading us today to envision the notions of distance and presence, and possibly to redefine them. Thus, can we still oppose physical distance to psychological distance? Can we still affirm that the physical absence does not permit a psychological co-presence in certain interactions, like this observed in video interviews? The results show that the psychological processes, activated in this context, are similar to those observed in "traditional" clinical consults between the patient and the therapist. However, certain specifics have led us to consider the concept of distance, here influenced by the framework, and to observe its effects. This distance could possibly constitute a therapeutic lever for some patients, notably for those who have difficulties establishing the right psychological distance in their relationships with others. According to these results, can "distance" still be opposed to "presence", or could it be re-defined? This also opens up questions on the more general concept of digital relationships, and the definition of their specificities.

  18. Distance learning for similarity estimation

    NARCIS (Netherlands)

    Yu, J.; Amores, J.; Sebe, N.; Radeva, P.; Tian, Q.

    2008-01-01

    In this paper, we present a general guideline to find a better distance measure for similarity estimation based on statistical analysis of distribution models and distance functions. A new set of distance measures are derived from the harmonic distance, the geometric distance, and their generalized

  19. Stereoscopic distance perception

    Science.gov (United States)

    Foley, John M.

    1989-01-01

    Limited cue, open-loop tasks in which a human observer indicates distances or relations among distances are discussed. By open-loop tasks, it is meant tasks in which the observer gets no feedback as to the accuracy of the responses. What happens when cues are added and when the loop is closed are considered. The implications of this research for the effectiveness of visual displays is discussed. Errors in visual distance tasks do not necessarily mean that the percept is in error. The error could arise in transformations that intervene between the percept and the response. It is argued that the percept is in error. It is also argued that there exist post-perceptual transformations that may contribute to the error or be modified by feedback to correct for the error.

  20. Distances to Dark Clouds: Comparing Extinction Distances to Maser Parallax Distances

    CERN Document Server

    Foster, Jonathan B; Benjamin, Robert A; Hoare, Melvin G; Jackson, James M

    2012-01-01

    We test two different methods of using near-infrared extinction to estimate distances to dark clouds in the first quadrant of the Galaxy using large near infrared (2MASS and UKIDSS) surveys. VLBI parallax measurements of masers around massive young stars provide the most direct and bias-free measurement of the distance to these dark clouds. We compare the extinction distance estimates to these maser parallax distances. We also compare these distances to kinematic distances, including recent re-calibrations of the Galactic rotation curve. The extinction distance methods agree with the maser parallax distances (within the errors) between 66% and 100% of the time (depending on method and input survey) and between 85% and 100% of the time outside of the crowded Galactic center. Although the sample size is small, extinction distance methods reproduce maser parallax distances better than kinematic distances; furthermore, extinction distance methods do not suffer from the kinematic distance ambiguity. This validatio...

  1. Sets avoiding integral distances

    CERN Document Server

    Kurz, Sascha

    2012-01-01

    We study open point sets in Euclidean spaces $\\mathbb{R}^d$ without a pair of points an integral distance apart. By a result of Furstenberg, Katznelson, and Weiss such sets must be of Lebesgue upper density zero. We are interested in how large such sets can be in $d$-dimensional volume. We determine the lower and upper bounds for the volumes of the sets in terms of the number of their connected components and dimension, and also give some exact values. Our problem can be viewed as a kind of inverse to known problems on sets with pairwise rational or integral distances.

  2. Distance Teaching on Bornholm

    DEFF Research Database (Denmark)

    Hansen, Finn J. S.; Clausen, Christian

    2001-01-01

    The case study represents an example of a top-down introduction of distance teaching as part of Danish trials with the introduction of multimedia in education. The study is concerned with the background, aim and context of the trial as well as the role and working of the technology and the organi......The case study represents an example of a top-down introduction of distance teaching as part of Danish trials with the introduction of multimedia in education. The study is concerned with the background, aim and context of the trial as well as the role and working of the technology...

  3. Distances to star forming regions

    CERN Document Server

    Loinard, Laurent

    2014-01-01

    The determination of accurate distances to star-forming regions are discussed in the broader historical context of astronomical distance measurements. We summarize recent results for regions within 1 kpc and present perspectives for the near and more distance future.

  4. Signaling Over Distances.

    Science.gov (United States)

    Saito, Atsushi; Cavalli, Valeria

    2016-02-01

    Neurons are extremely polarized cells. Axon lengths often exceed the dimension of the neuronal cell body by several orders of magnitude. These extreme axonal lengths imply that neurons have mastered efficient mechanisms for long distance signaling between soma and synaptic terminal. These elaborate mechanisms are required for neuronal development and maintenance of the nervous system. Neurons can fine-tune long distance signaling through calcium wave propagation and bidirectional transport of proteins, vesicles, and mRNAs along microtubules. The signal transmission over extreme lengths also ensures that information about axon injury is communicated to the soma and allows for repair mechanisms to be engaged. This review focuses on the different mechanisms employed by neurons to signal over long axonal distances and how signals are interpreted in the soma, with an emphasis on proteomic studies. We also discuss how proteomic approaches could help further deciphering the signaling mechanisms operating over long distance in axons. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  5. Weighted Feature Distance

    DEFF Research Database (Denmark)

    Ortiz-Arroyo, Daniel; Yazdani, Hossein

    2017-01-01

    The accuracy of machine learning methods for clustering depends on the optimal selection of similarity functions. Conventional distance functions for the vector space might cause an algorithm to being affected by some dominant features that may skew its final results. This paper introduces a flexib...

  6. Encyclopedia of Distance Learning

    Science.gov (United States)

    Howard, Caroline, Ed.; Boettecher, Judith, Ed.; Justice, Lorraine, Ed.; Schenk, Karen, Ed.; Rogers, Patricia, Ed.; Berg, Gary, Ed.

    2005-01-01

    The innovations in computer and communications technologies combined with on-going needs to deliver educational programs to students regardless of their physical locations, have lead to the innovation of distance education programs and technologies. To keep up with recent developments in both areas of technologies and techniques related to…

  7. Accreditation of Distance Learning

    Science.gov (United States)

    Demirel, Ergün

    2016-01-01

    The higher education institutes aspire to gain reputation of quality having accreditation from internationally recognized awarding bodies. The accreditation leads and provides quality assurance for education. Although distance learning becomes a significant part of the education system in the 21st century, there is still a common opinion that the…

  8. Prospect of Distance Learning

    Science.gov (United States)

    Rahman, Monsurur; Karim, Reza; Byramjee, Framarz

    2015-01-01

    Many educational institutions in the United States are currently offering programs through distance learning, and that trend is rising. In almost all spheres of education a developing country like Bangladesh needs to make available the expertise of the most qualified faculty to her distant people. But the fundamental question remains as to whether…

  9. Rapport in Distance Education

    Science.gov (United States)

    Murphy, Elizabeth; Rodriguez-Manzanares, Maria A.

    2012-01-01

    Rapport has been recognized as important in learning in general but little is known about its importance in distance education (DE). The study we report on in this paper provides insights into the importance of rapport in DE as well as challenges to and indicators of rapport-building in DE. The study relied on interviews with 42 Canadian…

  10. Misconceptions of Astronomical Distances

    Science.gov (United States)

    Miller, Brian W.; Brewer, William F.

    2010-01-01

    Previous empirical studies using multiple-choice procedures have suggested that there are misconceptions about the scale of astronomical distances. The present study provides a quantitative estimate of the nature of this misconception among US university students by asking them, in an open-ended response format, to make estimates of the distances…

  11. Distance Concentration-Based Artificial Immune Algorithm

    Institute of Scientific and Technical Information of China (English)

    LIU Tao; WANG Yao-cai; WANG Zhi-jie; MENG Jiang

    2005-01-01

    The diversity, adaptation and memory of biological immune system attract much attention of researchers. Several optimal algorithms based on immune system have also been proposed up to now. The distance concentration-based artificial immune algorithm (DCAIA) is proposed to overcome defects of the classical artificial immune algorithm (CAIA) in this paper. Compared with genetic algorithm (GA) and CAIA, DCAIA is good for solving the problem of precocity,holding the diversity of antibody, and enhancing convergence rate.

  12. Comparison of multiallelic distances for the quantification of genetic diversity in the papaya = Comparação de distâncias multi-alélicas sobre a quantificação da diversidade genética em mamão

    Directory of Open Access Journals (Sweden)

    Helaine Christine Cancela Ramos

    2011-01-01

    Full Text Available This study aimed to compare multiallelic distances to quantify genetic diversity in papaya. We evaluated forty-three individuals in the S2 generation, from the backcross between F1 (Cariflora x SS783 and Cariflora, and four accessions from the UENF/Caliman GermplasmBank. Genetic distances used were Smouse and Peakall (1999, Kosman and Leonard (2005 and weighted index. Clustering among genotypes was performed using the hierarchical unweighted pair-group method with arithmetic mean analysis (UPGMA and projection of the distance onthe bidimensional plan. A high correlation between genetic distances was observed; however, through UPGMA group analysis, the distance determined by the weighted index provided the complete separation of 52BC1S2-08, 52BC1S2-29 and 52BC1S2-34 inbred lines. Throughprojection of distances in the plan, Kosman and Leonard (2005 coefficients and weighted allowed the differentiation of individuals in the S2 generation (52BC1S2-08, 52BC1S2-29 and 52BC1S2-34, the progenitor (‘Cariflora’ and ‘SS783’, and the four germplasm bank accessions in a different manner than the Smouse and Peakall (1999 index, which did not provide this discrimination among the accessed genotypes. We conclude that the Kosman and Leonard (2005 coefficient and weighted index are more efficient than the Smouse and Peakall (1999 algorithm on the disposition of the accessed genotypes in dendrograms and in the Cartesian axis displaying genetic similarity.O presente trabalho visou à comparação de distâncias multi-alélicas sobre a quantificação da diversidade genética em mamão. Para tanto, foram avaliados 43 indivíduos da geração S2, oriunda do retrocruzamento entre F1 dos (‘Cariflora’ x ‘SS783’ e ‘Cariflora’, e quatro acessos do Banco de Germoplasma da UENF/Caliman. As distâncias genéticas utilizadas foram: Smouse e Peakall (1999, Kosman e Leonard (2005 e índice ponderado. Posteriormente foi realizado o agrupamento entre os gen

  13. Fuzzy clustering with Minkowski distance

    NARCIS (Netherlands)

    P.J.F. Groenen (Patrick); U. Kaymak (Uzay); J.M. van Rosmalen (Joost)

    2006-01-01

    textabstractDistances in the well known fuzzy c-means algorithm of Bezdek (1973) are measured by the squared Euclidean distance. Other distances have been used as well in fuzzy clustering. For example, Jajuga (1991) proposed to use the L_1-distance and Bobrowski and Bezdek (1991) also used the L_inf

  14. The sound of distance.

    Science.gov (United States)

    Rabaglia, Cristina D; Maglio, Sam J; Krehm, Madelaine; Seok, Jin H; Trope, Yaacov

    2016-07-01

    Human languages may be more than completely arbitrary symbolic systems. A growing literature supports sound symbolism, or the existence of consistent, intuitive relationships between speech sounds and specific concepts. Prior work establishes that these sound-to-meaning mappings can shape language-related judgments and decisions, but do their effects generalize beyond merely the linguistic and truly color how we navigate our environment? We examine this possibility, relating a predominant sound symbolic distinction (vowel frontness) to a novel associate (spatial proximity) in five studies. We show that changing one vowel in a label can influence estimations of distance, impacting judgment, perception, and action. The results (1) provide the first experimental support for a relationship between vowels and spatial distance and (2) demonstrate that sound-to-meaning mappings have outcomes that extend beyond just language and can - through a single sound - influence how we perceive and behave toward objects in the world. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Tolman's Luminosity-Distance, Poincare's Light-Distance and Cayley-Klein's Hyperbolic Distance

    CERN Document Server

    Pierseaux, Yves

    2009-01-01

    We deduce Tolman's formula of luminosity-distance in Cosmology from Poincare's definition of light-distance with Lorentz Transformation (LT).In Minkowskian metric, if distance is proper time (as it is often argued) then light-distance must be also the shortest distance, like proper duration (unlike Einstein's longest length within rest system). By introducing Poincare's proper light-distance in Einstein's basic synchronization we deduce a dilated distance between observer and receding mirror (with relativistic Doppler factor). Such a distance corresponds not to an Euclidean distance (Einstein's rigid rod) but to an Hyperbolic distance (Cayley-Klein) with a Lobatchevskian Horizon. From a basic proportionality hyperbolic distance-velocity, we deduce the law of Hubble. By following Penrose's Lobatchevskian representation of LT, we transform Special Relativity (SR) into an Hyperbolic Cosmological Relativity (HCR). by using only the LT but the whole LT. In Hyperbolic Rotation motion (basic active LT or Einstein's ...

  16. Distance, Borders, and Time

    DEFF Research Database (Denmark)

    Skillicorn, David; Walther, Olivier; Zheng, Quan

    is a combination of the physical geography of the target environment, and the mental and physical cost of following a seemingly random pattern of attacks. Focusing on the distance and time between attacks and taking into consideration the transaction costs that state boundaries impose, we wish to understand what......” of North and West Africa that depicts the permeability to violence. A better understanding of how location, time, and borders condition attacks enables planning, prepositioning, and response....

  17. A Distance Measure for Genome Phylogenetic Analysis

    Science.gov (United States)

    Cao, Minh Duc; Allison, Lloyd; Dix, Trevor

    Phylogenetic analyses of species based on single genes or parts of the genomes are often inconsistent because of factors such as variable rates of evolution and horizontal gene transfer. The availability of more and more sequenced genomes allows phylogeny construction from complete genomes that is less sensitive to such inconsistency. For such long sequences, construction methods like maximum parsimony and maximum likelihood are often not possible due to their intensive computational requirement. Another class of tree construction methods, namely distance-based methods, require a measure of distances between any two genomes. Some measures such as evolutionary edit distance of gene order and gene content are computational expensive or do not perform well when the gene content of the organisms are similar. This study presents an information theoretic measure of genetic distances between genomes based on the biological compression algorithm expert model. We demonstrate that our distance measure can be applied to reconstruct the consensus phylogenetic tree of a number of Plasmodium parasites from their genomes, the statistical bias of which would mislead conventional analysis methods. Our approach is also used to successfully construct a plausible evolutionary tree for the γ-Proteobacteria group whose genomes are known to contain many horizontally transferred genes.

  18. Monge Distance between Quantum States

    CERN Document Server

    Zyczkowski, K; Zyczkowski, Karol; Slomczynski, Wojciech

    1998-01-01

    We define a metric in the space of quantum states taking the Monge distance between corresponding Husimi distributions (Q--functions). This quantity fulfills the axioms of a metric and satisfies the following semiclassical property: the distance between two coherent states is equal to the Euclidean distance between corresponding points in the classical phase space. We compute analytically distances between certain states (coherent, squeezed, Fock and thermal) and discuss a scheme for numerical computation of Monge distance for two arbitrary quantum states.

  19. The DDO IVC Distance Project

    CERN Document Server

    Gladders, M D; Burns, C R; Attard, A; Casey, M P; Hamilton, D; Mallén-Ornelas, G; Karr, J L; Poirier, S M; Sawicki, M; Barrientos, F; Barkhouse, W A; Brodwin, M; Clark, J; McNaughton, R; Ruetalo-Pacheco, M; Mochnacki, S W; Gladders, Michael D.; Clarke, Tracy E.; Burns, Christopher R.; Attard, Allen; Casey, Michael P.; Hamilton, Devon; Mallen-Ornelas, Gabriela; Karr, Jennifer L.; Poirier, Sara M.; Sawicki, Marcin; Barrientos, Felipe; Barkhouse, Wayne; Brodwin, Mark; Clark, Jason; Naughton, Rosemary Mc; Ruetalo-Pacheco, Marcelo; Mochnacki, Stefan W.

    1998-01-01

    We present the first set of distance limits from the David Dunlap Observatory Intermediate Velocity Cloud (DDO IVC) distance project. Such distance measures are crucial to understanding the origins and dynamics of IVCs, as the distances set most of the basic physical parameters for the clouds. Currently there are very few IVCs with reliably known distances. This paper describes in some detail the basic techniques used to measure distances, with particular emphasis on the the analysis of interstellar absorption line data, which forms the basis of our distance determinations. As an example, we provide a detailed description of our distance determination for the Draco Cloud. Preliminary distance limits for a total of eleven clouds are provided.

  20. Advanced hierarchical distance sampling

    Science.gov (United States)

    Royle, Andy

    2016-01-01

    In this chapter, we cover a number of important extensions of the basic hierarchical distance-sampling (HDS) framework from Chapter 8. First, we discuss the inclusion of “individual covariates,” such as group size, in the HDS model. This is important in many surveys where animals form natural groups that are the primary observation unit, with the size of the group expected to have some influence on detectability. We also discuss HDS integrated with time-removal and double-observer or capture-recapture sampling. These “combined protocols” can be formulated as HDS models with individual covariates, and thus they have a commonality with HDS models involving group structure (group size being just another individual covariate). We cover several varieties of open-population HDS models that accommodate population dynamics. On one end of the spectrum, we cover models that allow replicate distance sampling surveys within a year, which estimate abundance relative to availability and temporary emigration through time. We consider a robust design version of that model. We then consider models with explicit dynamics based on the Dail and Madsen (2011) model and the work of Sollmann et al. (2015). The final major theme of this chapter is relatively newly developed spatial distance sampling models that accommodate explicit models describing the spatial distribution of individuals known as Point Process models. We provide novel formulations of spatial DS and HDS models in this chapter, including implementations of those models in the unmarked package using a hack of the pcount function for N-mixture models.

  1. Distance Metric Tracking

    Science.gov (United States)

    2016-03-02

    520, 2004. 16 [12] E.C. Hall and R.M. Willett. Online convex optimization in dynamic environ- ments. Selected Topics in Signal Processing, IEEE Journal...Conference on Machine Learning, pages 1160–1167. ACM, 2008. [25] Eric P Xing, Michael I Jordan, Stuart Russell, and Andrew Y Ng. Distance metric...whereBψ is any Bregman divergence and ηt is the learning rate parameter. From ( Hall & Willett, 2015) we have: Theorem 1. G` = max θ∈Θ,`∈L ‖∇f(θ)‖ φmax = 1

  2. Long distance tunneling

    CERN Document Server

    Ivlev, B I

    2005-01-01

    Quantum tunneling between two potential wells in a magnetic field can be strongly increased when the potential barrier varies in the direction perpendicular to the line connecting the two wells and remains constant along this line. A periodic structure of the wave function is formed in the direction joining the wells. The resulting motion can be coherent like motion in a conventional narrow band periodic structure. A particle penetrates the barrier over a long distance which strongly contrasts to WKB-like tunneling. The whole problem is stationary. The coherent process can be influenced by dissipation.

  3. Distances on Lozenge Tilings

    CERN Document Server

    Bodini, Olivier; Fernique, Thomas

    2009-01-01

    In this paper, a structural property of the set of lozenge tilings of a 2n-gon is highlighted. We introduce a simple combinatorial value called Hamming-distance, which is a lower bound for the flipdistance (i.e. the number of necessary local transformations involving three lozenges) between two given tilings. It is here proven that, for n5, We show that there is some deficient pairs of tilings for which the flip connection needs more flips than the combinatorial lower bound indicates.

  4. Distance Teaching on Bornholm

    DEFF Research Database (Denmark)

    Hansen, Finn J. S.; Clausen, Christian

    2001-01-01

    and the organisational set-up. It is debated which kind of social learning that has taken place. The innovation process was based on the implementation of an inflexible video-conference system without any proactive considerations of organisational change or pedagocical development. User appropriation of the technology......The case study represents an example of a top-down introduction of distance teaching as part of Danish trials with the introduction of multimedia in education. The study is concerned with the background, aim and context of the trial as well as the role and working of the technology...

  5. Distance Learning. Volume I: Distance Learning Analysis Study.

    Science.gov (United States)

    1998-09-01

    The primary focus of this project is the determination of the feasibility and cost effectiveness of applying Distance Learning strategies to 22...selected PPSCP courses and development of a Distance Learning Analysis Procedures Manual.

  6. PERBANDINGAN EUCLIDEAN DISTANCE DENGAN CANBERRA DISTANCE PADA FACE RECOGNITION

    Directory of Open Access Journals (Sweden)

    Sendhy Rachmat Wurdianarto

    2014-08-01

    Full Text Available Perkembangan ilmu pada dunia komputer sangatlah pesat. Salah satu yang menandai hal ini adalah ilmu komputer telah merambah pada dunia biometrik. Arti biometrik sendiri adalah karakter-karakter manusia yang dapat digunakan untuk membedakan antara orang yang satu dengan yang lainnya. Salah satu pemanfaatan karakter / organ tubuh pada setiap manusia yang digunakan untuk identifikasi (pengenalan adalah dengan memanfaatkan wajah. Dari permasalahan diatas dalam pengenalan lebih tentang aplikasi Matlab pada Face Recognation menggunakan metode Euclidean Distance dan Canberra Distance. Model pengembangan aplikasi yang digunakan adalah model waterfall. Model waterfall beriisi rangkaian aktivitas proses yang disajikan dalam proses analisa kebutuhan, desain menggunakan UML (Unified Modeling Language, inputan objek gambar diproses menggunakan Euclidean Distance dan Canberra Distance. Kesimpulan yang dapat ditarik adalah aplikasi face Recognation menggunakan metode euclidean Distance dan Canverra Distance terdapat kelebihan dan kekurangan masing-masing. Untuk kedepannya aplikasi tersebut dapat dikembangkan dengan menggunakan objek berupa video ataupun objek lainnya.   Kata kunci : Euclidean Distance, Face Recognition, Biometrik, Canberra Distance

  7. Minimal distances between SCFTs

    Energy Technology Data Exchange (ETDEWEB)

    Buican, Matthew [Department of Physics and Astronomy, Rutgers University,Piscataway, NJ 08854 (United States)

    2014-01-28

    We study lower bounds on the minimal distance in theory space between four-dimensional superconformal field theories (SCFTs) connected via broad classes of renormalization group (RG) flows preserving various amounts of supersymmetry (SUSY). For N=1 RG flows, the ultraviolet (UV) and infrared (IR) endpoints of the flow can be parametrically close. On the other hand, for RG flows emanating from a maximally supersymmetric SCFT, the distance to the IR theory cannot be arbitrarily small regardless of the amount of (non-trivial) SUSY preserved along the flow. The case of RG flows from N=2 UV SCFTs is more subtle. We argue that for RG flows preserving the full N=2 SUSY, there are various obstructions to finding examples with parametrically close UV and IR endpoints. Under reasonable assumptions, these obstructions include: unitarity, known bounds on the c central charge derived from associativity of the operator product expansion, and the central charge bounds of Hofman and Maldacena. On the other hand, for RG flows that break N=2→N=1, it is possible to find IR fixed points that are parametrically close to the UV ones. In this case, we argue that if the UV SCFT possesses a single stress tensor, then such RG flows excite of order all the degrees of freedom of the UV theory. Furthermore, if the UV theory has some flavor symmetry, we argue that the UV central charges should not be too large relative to certain parameters in the theory.

  8. The Distance to M51

    CERN Document Server

    McQuinn, Kristen B W; Dolphin, Andrew E; Berg, Danielle; Kennicutt, Robert

    2016-01-01

    Great investments of observing time have been dedicated to the study of nearby spiral galaxies with diverse goals ranging from understanding the star formation process to characterizing their dark matter distributions. Accurate distances are fundamental to interpreting observations of these galaxies, yet many of the best studied nearby galaxies have distances based on methods with relatively large uncertainties. We have started a program to derive accurate distances to these galaxies. Here we measure the distance to M51 - the Whirlpool galaxy - from newly obtained Hubble Space Telescope optical imaging using the tip of the red giant branch method. We measure the distance modulus to be 8.58+/-0.10 Mpc (statistical), corresponding to a distance modulus of 29.67+/-0.02 mag. Our distance is an improvement over previous results as we use a well-calibrated, stable distance indicator, precision photometry in a optimally selected field of view, and a Bayesian Maximum Likelihood technique that reduces measurement unce...

  9. Improved directional-distance filter

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    This paper proposes a new spatial-distance weighting function.By combining the weighting function and the traditional directional-distance filter (DDF) in a novel way,a new vector filter-the adaptive distance-weighted directional-distance filter (ADWDDF)-is presented.The experimental results show that the proposed solution provides better filtering performance and preserves better image chromaticity and edge or detail information compared with the traditional DDF and some other typical vector filters.

  10. Comparison of hybrid vigor based on parental distance in SSR markers and agronomic traits in mungbean (Vigna radiata (L. Wilczek

    Directory of Open Access Journals (Sweden)

    Worawit Sorajjapinun

    2012-02-01

    Full Text Available Heterosis of seed yield in mungbean (Vigna radiata (L. Wilczek has created an interest among plant breeders todevelop hybrid mungbean cultivars. The objective of this study was to compare levels of heterosis among four F1 hybrids ofmungbeans with different genetic distance. The hybrids were developed by using Sukhothai (SKT as the female parent andpollinated by male parents of different genetic distance as revealed by SSR markers. They were H192 (close distance, C357(moderate distance, TC1965 (high distance and W166 (very high distance. The results revealed that the F1 from the parentswith larger genetic distance showed higher heterosis in yield per plant and number of pods per plant. Thus SSR markerscombined with yield components can be used to identify parental lines with high genetic distance for hybrid seed productionin mungbean. This approach potentially helps to reduce the amount of fieldwork required for evaluation of F1 hybrids.

  11. Reconsidering Moore's Transactional Distance Theory

    Science.gov (United States)

    Giossos, Yiannis; Koutsouba, Maria; Lionarakis, Antonis; Skavantzos, Kosmas

    2009-01-01

    One of the core theories of distance education is Michael Graham Moore's "Theory of Transactional Distance" that provides the broad framework of the pedagogy of distance education and allows the generation of almost infinite number of hypotheses for research. However, the review of the existing studies relating to the theory showed the use of a…

  12. Robust Estimation of Evolutionary Distances with Information Theory.

    Science.gov (United States)

    Cao, Minh Duc; Allison, Lloyd; Dix, Trevor I; Bodén, Mikael

    2016-05-01

    Methods for measuring genetic distances in phylogenetics are known to be sensitive to the evolutionary model assumed. However, there is a lack of established methodology to accommodate the trade-off between incorporating sufficient biological reality and avoiding model overfitting. In addition, as traditional methods measure distances based on the observed number of substitutions, their tend to underestimate distances between diverged sequences due to backward and parallel substitutions. Various techniques were proposed to correct this, but they lack the robustness against sequences that are distantly related and of unequal base frequencies. In this article, we present a novel genetic distance estimate based on information theory that overcomes the above two hurdles. Instead of examining the observed number of substitutions, this method estimates genetic distances using Shannon's mutual information. This naturally provides an effective framework for balancing model complexity and goodness of fit. Our distance estimate is shown to be approximately linear to elapsed time and hence is less sensitive to the divergence of sequence data and compositional biased sequences. Using extensive simulation data, we show that our method 1) consistently reconstructs more accurate phylogeny topologies than existing methods, 2) is robust in extreme conditions such as diverged phylogenies, unequal base frequencies data, and heterogeneous mutation patterns, and 3) scales well with large phylogenies. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Keeping Your Distance is Hard

    OpenAIRE

    Burke, Kyle; Heubach, Silvia; Huggan, Melissa; Huntemann, Svenja

    2016-01-01

    We study the computational complexity of distance games, a class of combinatorial games played on graphs. A move consists of colouring an uncoloured vertex subject to it not being at certain distances determined by two sets, D and S. D is the set of forbidden distances for colouring vertices in different colors, while S is the set of forbidden distances for the same colour. The last player to move wins. Well-known examples of distance games are Node-Kayles, Snort, and Col, whose complexities ...

  14. Distance learning and perioperative nursing.

    Science.gov (United States)

    Gruendemann, Barbara J

    2007-03-01

    Distance learning in nursing education is arriving with unprecedented speed, which has led to much uncertainty among educators. This article provides an overview of distance learning and its application to perioperative nursing. Lack of face-to-face interaction is of foremost concern in distance learning, and educators must develop new teaching strategies to address this problem. Models for assessing outcomes and effectiveness are important tools to use when implementing a distance learning program. Basic perioperative nursing concepts, skills, procedures, and recommended practices can be introduced effectively with online distance learning modalities and then reinforced through a clinical component.

  15. New distances to RAVE stars

    CERN Document Server

    Binney, James; Kordopatis, Georges; McMillan, Paul J; Sharma, Sanjib; Zwitter, Tomaz; Bienayme, Olivier; Bland-Hawthorn, Joss; Steinmetz, Matthias; Gilmore, Gerry; Williams, Mary E K; Navarro, Julio; Grebel, Eva K; Helmi, Amina; Parker, Quentin; Reid, Warren A; Seabroke, George; Watson, Fred; Wyse, Rosie F G

    2013-01-01

    Probability density functions are determined from new stellar parameters for the distance moduli of stars for which the RAdial Velocity Experiment (RAVE) has obtained spectra with S/N>=10. The expectation value of distance is larger than the distance implied by the expectation of distance modulus; the latter is itself larger than the distance implied by the expectation value of the parallax. Our parallaxes of Hipparcos stars agree well with the values measured by Hipparcos, so the expectation of parallax is the most reliable distance indicator. The latter are improved by taking extinction into account. We provide one- two- or three-Gaussian fits to the distance pdfs. The effective temperature absolute-magnitude diagram of our stars is significantly improved when these pdfs are used to make the diagram. We use the method of kinematic corrections devised by Schoenrich, Binney & Asplund to check for systematic errors in our estimators for ordinary stars and confirm the conclusion reached from the Hipparcos s...

  16. Fast computation of distance estimators

    Directory of Open Access Journals (Sweden)

    Lagergren Jens

    2007-03-01

    Full Text Available Abstract Background Some distance methods are among the most commonly used methods for reconstructing phylogenetic trees from sequence data. The input to a distance method is a distance matrix, containing estimated pairwise distances between all pairs of taxa. Distance methods themselves are often fast, e.g., the famous and popular Neighbor Joining (NJ algorithm reconstructs a phylogeny of n taxa in time O(n3. Unfortunately, the fastest practical algorithms known for Computing the distance matrix, from n sequences of length l, takes time proportional to l·n2. Since the sequence length typically is much larger than the number of taxa, the distance estimation is the bottleneck in phylogeny reconstruction. This bottleneck is especially apparent in reconstruction of large phylogenies or in applications where many trees have to be reconstructed, e.g., bootstrapping and genome wide applications. Results We give an advanced algorithm for Computing the number of mutational events between DNA sequences which is significantly faster than both Phylip and Paup. Moreover, we give a new method for estimating pairwise distances between sequences which contain ambiguity Symbols. This new method is shown to be more accurate as well as faster than earlier methods. Conclusion Our novel algorithm for Computing distance estimators provides a valuable tool in phylogeny reconstruction. Since the running time of our distance estimation algorithm is comparable to that of most distance methods, the previous bottleneck is removed. All distance methods, such as NJ, require a distance matrix as input and, hence, our novel algorithm significantly improves the overall running time of all distance methods. In particular, we show for real world biological applications how the running time of phylogeny reconstruction using NJ is improved from a matter of hours to a matter of seconds.

  17. Planning with Reachable Distances

    KAUST Repository

    Tang, Xinyu

    2009-01-01

    Motion planning for spatially constrained robots is difficult due to additional constraints placed on the robot, such as closure constraints for closed chains or requirements on end effector placement for articulated linkages. It is usually computationally too expensive to apply sampling-based planners to these problems since it is difficult to generate valid configurations. We overcome this challenge by redefining the robot\\'s degrees of freedom and constraints into a new set of parameters, called reachable distance space (RD-space), in which all configurations lie in the set of constraint-satisfying subspaces. This enables us to directly sample the constrained subspaces with complexity linear in the robot\\'s number of degrees of freedom. In addition to supporting efficient sampling, we show that the RD-space formulation naturally supports planning, and in particular, we design a local planner suitable for use by sampling-based planners. We demonstrate the effectiveness and efficiency of our approach for several systems including closed chain planning with multiple loops, restricted end effector sampling, and on-line planning for drawing/sculpting. We can sample single-loop closed chain systems with 1000 links in time comparable to open chain sampling, and we can generate samples for 1000-link multi-loop systems of varying topology in less than a second. © 2009 Springer-Verlag.

  18. Genetic Discrimination

    Science.gov (United States)

    ... in Genetics Archive Regulation of Genetic Tests Genetic Discrimination Overview Many Americans fear that participating in research ... I) and employment (Title II). Read more Genetic Discrimination and Other Laws Genetic Discrimination and Other Laws ...

  19. Distance learning for similarity estimation.

    Science.gov (United States)

    Yu, Jie; Amores, Jaume; Sebe, Nicu; Radeva, Petia; Tian, Qi

    2008-03-01

    In this paper, we present a general guideline to find a better distance measure for similarity estimation based on statistical analysis of distribution models and distance functions. A new set of distance measures are derived from the harmonic distance, the geometric distance, and their generalized variants according to the Maximum Likelihood theory. These measures can provide a more accurate feature model than the classical Euclidean and Manhattan distances. We also find that the feature elements are often from heterogeneous sources that may have different influence on similarity estimation. Therefore, the assumption of single isotropic distribution model is often inappropriate. To alleviate this problem, we use a boosted distance measure framework that finds multiple distance measures which fit the distribution of selected feature elements best for accurate similarity estimation. The new distance measures for similarity estimation are tested on two applications: stereo matching and motion tracking in video sequences. The performance of boosted distance measure is further evaluated on several benchmark data sets from the UCI repository and two image retrieval applications. In all the experiments, robust results are obtained based on the proposed methods.

  20. On distances between phylogenetic trees

    Energy Technology Data Exchange (ETDEWEB)

    DasGupta, B. [Rutgers Univ., Camden, NJ (United States); He, X. [SUNY, Buffalo, NY (United States); Jiang, T. [McMaster Univ., Hamilton, Ontario (Canada)] [and others

    1997-06-01

    Different phylogenetic trees for the same group of species are often produced either by procedures that use diverse optimality criteria or from different genes in the study of molecular evolution. Comparing these trees to find their similarities and dissimilarities, i.e. distance, is thus an important issue in computational molecular biology. The nearest neighbor interchange distance and the subtree-transfer distance are two major distance metrics that have been proposed and extensively studied for different reasons. Despite their many appealing aspects such as simplicity and sensitivity to tree topologies, computing these distances has remained very challenging. This article studies the complexity and efficient approximation algorithms for computing the nni distance and a natural extension of the subtree-transfer distance, called the linear-cost subtree-transfer distance. The linear-cost subtree-transfer model is more logical than the subtree-transfer model and in fact coincides with the nni model under certain conditions. The following results have been obtained as part of our project of building a comprehensive software package for computing distances between phylogenies. (1) Computing the nni distance is NP-complete. This solves a 25 year old open question appearing again and again in, for example, under the complexity-theoretic assumption of P {ne} NP. We also answer an open question regarding the nni distance between unlabeled trees for which an erroneous proof appeared in. We give an algorithm to compute the optimal nni sequence in time O(n{sup 2} logn + n {circ} 2{sup O(d)}), where the nni distance is at most d. (2) Biological applications require us to extend the nni and linear-cost subtree-transfer models to weighted phylogenies, where edge weights indicate the length of evolution along each edge. We present a logarithmic ratio approximation algorithm for nni and a ratio 2 approximation algorithm for linear-cost subtree-transfer, on weighted trees.

  1. DISTANCE EDUCATOR: A Multiskill Personality

    Directory of Open Access Journals (Sweden)

    Sangeeta MALIK

    2013-01-01

    Full Text Available When we talk about a distance educator and a conventional educator the difference we found nd about both of them is that, a distance educator needs to play multiple roles as compared to a conventional educator. They require more skills and knowledge cater to the needs of the learner. In this article we will cover all the responsible areas of a distance educator & why we should consider them as a multiskill personality?

  2. Doctoral education from a distance.

    Science.gov (United States)

    Effken, Judith A

    2008-12-01

    This article describes the environmental factors that have contributed to the recent rapid growth of nursing doctoral education at a distance. Early and recent efforts to deliver distance doctoral education are discussed, using The University of Arizona College of Nursing experience as the key exemplar. The Community of Inquiry model is introduced as an appropriate model for doctoral education and then used as a framework to evaluate the current state of the art in distance doctoral nursing education. Successes and challenges in delivering doctoral education from a distance are described.

  3. The Extended Edit Distance Metric

    CERN Document Server

    Fuad, Muhammad Marwan Muhammad

    2007-01-01

    Similarity search is an important problem in information retrieval. This similarity is based on a distance. Symbolic representation of time series has attracted many researchers recently, since it reduces the dimensionality of these high dimensional data objects. We propose a new distance metric that is applied to symbolic data objects and we test it on time series data bases in a classification task. We compare it to other distances that are well known in the literature for symbolic data objects. We also prove, mathematically, that our distance is metric.

  4. Transactional Distance and Autonomy in a Distance Learning Environment

    Science.gov (United States)

    Vasiloudis, G.; Koutsouba, M.; Giossos, Y.; Mavroidis, I.

    2015-01-01

    This paper studies the transactional distance between the students and the tutor as well as the autonomy of students in a postgraduate course of the Hellenic Open University (HOU). The aim of the paper is to examine how the relation between autonomy and transactional distance evolves during an academic year and how this relation is affected by…

  5. Distance spectra and Distance energy of Integral Circulant Graphs

    CERN Document Server

    c, Aleksandar Ili\\'

    2011-01-01

    The distance energy of a graph $G$ is a recently developed energy-type invariant, defined as the sum of absolute values of the eigenvalues of the distance matrix of $G$. There was a vast research for the pairs and families of non-cospectral graphs having equal distance energy, and most of these constructions were based on the join of graphs. A graph is called circulant if it is Cayley graph on the circulant group, i.e. its adjacency matrix is circulant. A graph is called integral if all eigenvalues of its adjacency matrix are integers. Integral circulant graphs play an important role in modeling quantum spin networks supporting the perfect state transfer. In this paper, we characterize the distance spectra of integral circulant graphs and prove that these graphs have integral eigenvalues of distance matrix $D$. Furthermore, we calculate the distance spectra and distance energy of unitary Cayley graphs. In conclusion, we present two families of pairs $(G_1, G_2)$ of integral circulant graphs with equal distanc...

  6. Generalising Ward’s Method for Use with Manhattan Distances

    Science.gov (United States)

    Strauss, Trudie; von Maltitz, Michael Johan

    2017-01-01

    The claim that Ward’s linkage algorithm in hierarchical clustering is limited to use with Euclidean distances is investigated. In this paper, Ward’s clustering algorithm is generalised to use with l1 norm or Manhattan distances. We argue that the generalisation of Ward’s linkage method to incorporate Manhattan distances is theoretically sound and provide an example of where this method outperforms the method using Euclidean distances. As an application, we perform statistical analyses on languages using methods normally applied to biology and genetic classification. We aim to quantify differences in character traits between languages and use a statistical language signature based on relative bi-gram (sequence of two letters) frequencies to calculate a distance matrix between 32 Indo-European languages. We then use Ward’s method of hierarchical clustering to classify the languages, using the Euclidean distance and the Manhattan distance. Results obtained from using the different distance metrics are compared to show that the Ward’s algorithm characteristic of minimising intra-cluster variation and maximising inter-cluster variation is not violated when using the Manhattan metric. PMID:28085891

  7. Virtual Bioinformatics Distance Learning Suite

    Science.gov (United States)

    Tolvanen, Martti; Vihinen, Mauno

    2004-01-01

    Distance learning as a computer-aided concept allows students to take courses from anywhere at any time. In bioinformatics, computers are needed to collect, store, process, and analyze massive amounts of biological and biomedical data. We have applied the concept of distance learning in virtual bioinformatics to provide university course material…

  8. The Psychology of Psychic Distance

    DEFF Research Database (Denmark)

    Håkanson, Lars; Ambos, Björn; Schuster, Anja

    2016-01-01

    and their theoretical underpinnings assume psychic distances to be symmetric. Building on insights from psychology and sociology, this paper demonstrates how national factors and cognitive processes interact in the formation of asymmetric distance perceptions. The results suggest that exposure to other countries...

  9. The Distance to M104

    Science.gov (United States)

    McQuinn, Kristen. B. W.; Skillman, Evan D.; Dolphin, Andrew E.; Berg, Danielle; Kennicutt, Robert

    2016-11-01

    M104 (NGC 4594; the Sombrero galaxy) is a nearby, well-studied elliptical galaxy included in scores of surveys focused on understanding the details of galaxy evolution. Despite the importance of observations of M104, a consensus distance has not yet been established. Here, we use newly obtained Hubble Space Telescope optical imaging to measure the distance to M104 based on the tip of the red giant branch (TRGB) method. Our measurement yields the distance to M104 to be 9.55 ± 0.13 ± 0.31 Mpc equivalent to a distance modulus of 29.90 ± 0.03 ± 0.07 mag. Our distance is an improvement over previous results as we use a well-calibrated, stable distance indicator, precision photometry in a optimally selected field of view, and a Bayesian maximum likelihood technique that reduces measurement uncertainties. The most discrepant previous results are due to Tully-Fisher method distances, which are likely inappropriate for M104 given its peculiar morphology and structure. Our results are part of a larger program to measure accurate distances to a sample of well-known spiral galaxies (including M51, M74, and M63) using the TRGB method. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained from the Data Archive at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

  10. The Distance to M51

    Science.gov (United States)

    McQuinn, Kristen. B. W.; Skillman, Evan D.; Dolphin, Andrew E.; Berg, Danielle; Kennicutt, Robert

    2016-07-01

    Great investments of observing time have been dedicated to the study of nearby spiral galaxies with diverse goals ranging from understanding the star formation process to characterizing their dark matter distributions. Accurate distances are fundamental to interpreting observations of these galaxies, yet many of the best studied nearby galaxies have distances based on methods with relatively large uncertainties. We have started a program to derive accurate distances to these galaxies. Here we measure the distance to M51—the Whirlpool galaxy—from newly obtained Hubble Space Telescope optical imaging using the tip of the red giant branch method. We measure the distance modulus to be 8.58 ± 0.10 Mpc (statistical), corresponding to a distance modulus of 29.67 ± 0.02 mag. Our distance is an improvement over previous results as we use a well-calibrated, stable distance indicator, precision photometry in a optimally selected field of view, and a Bayesian Maximum Likelihood technique that reduces measurement uncertainties. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained from the Data Archive at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

  11. Quality Content in Distance Education

    Science.gov (United States)

    Yildiz, Ezgi Pelin; Isman, Aytekin

    2016-01-01

    In parallel with technological advances in today's world of education activities can be conducted without the constraints of time and space. One of the most important of these activities is distance education. The success of the distance education is possible with content quality. The proliferation of e-learning environment has brought a need for…

  12. Virtual Bioinformatics Distance Learning Suite

    Science.gov (United States)

    Tolvanen, Martti; Vihinen, Mauno

    2004-01-01

    Distance learning as a computer-aided concept allows students to take courses from anywhere at any time. In bioinformatics, computers are needed to collect, store, process, and analyze massive amounts of biological and biomedical data. We have applied the concept of distance learning in virtual bioinformatics to provide university course material…

  13. Distance labeling schemes for trees

    DEFF Research Database (Denmark)

    Alstrup, Stephen; Gørtz, Inge Li; Bistrup Halvorsen, Esben;

    2016-01-01

    We consider distance labeling schemes for trees: given a tree with n nodes, label the nodes with binary strings such that, given the labels of any two nodes, one can determine, by looking only at the labels, the distance in the tree between the two nodes. A lower bound by Gavoille et al. [Gavoill...

  14. New distances to RAVE stars

    NARCIS (Netherlands)

    Binney, J.; Burnett, B.; Kordopatis, G.; McMillan, P. J.; Sharma, S.; Zwitter, T.; Bienayme, O.; Bland-Hawthorn, J.; Steinmetz, M.; Gilmore, G.; Williams, M. E. K.; Navarro, J.; Grebel, E. K.; Helmi, A.; Parker, Q.; Reid, W. A.; Seabroke, G.; Watson, F.; Wyse, R. F. G.

    Probability density functions (pdfs) are determined from new stellar parameters for the distance moduli of stars for which the RAdial Velocity Experiment (RAVE) has obtained spectra with S/N >= 10. Single-Gaussian fits to the pdf in distance modulus suffice for roughly half the stars, with most of

  15. Distance labeling schemes for trees

    DEFF Research Database (Denmark)

    Alstrup, Stephen; Gørtz, Inge Li; Bistrup Halvorsen, Esben

    2016-01-01

    variants such as, for example, small distances in trees [Alstrup et al., SODA, 2003]. We improve the known upper and lower bounds of exact distance labeling by showing that 1/4 log2(n) bits are needed and that 1/2 log2(n) bits are sufficient. We also give (1 + ε)-stretch labeling schemes using Theta...

  16. Faculty Attitudes about Distance Education

    Science.gov (United States)

    Smidt, Esther; McDyre, Brian; Bunk, Jennifer; Li, Rui; Gatenby, Tanya

    2014-01-01

    In recent years, there has been a dramatic increase in distance learning in higher education. Given this, it is extremely important to understand faculty attitudes about distance education, not only because they can vary widely, but also because it is the faculty, through their design and implementation of online courses, that will shape the…

  17. Distance-constrained grid colouring

    Directory of Open Access Journals (Sweden)

    Aszalós László

    2016-06-01

    Full Text Available Distance-constrained colouring is a mathematical model of the frequency assignment problem. This colouring can be treated as an optimization problem so we can use the toolbar of the optimization to solve concrete problems. In this paper, we show performance of distance-constrained grid colouring for two methods which are good in map colouring.

  18. Hierarchical traits distances explain grassland Fabaceae species’ ecological niches distances

    Directory of Open Access Journals (Sweden)

    Florian eFort

    2015-02-01

    Full Text Available Fabaceae species play a key role in ecosystem functioning through their capacity to fix atmospheric nitrogen via their symbiosis with Rhizobium bacteria. To increase benefits of using Fabaceae in agricultural systems, it is necessary to find ways to evaluate species or genotypes having potential adaptations to sub-optimal growth conditions. We evaluated the relevance of phylogenetic distance, absolute trait distance and hierarchical trait distance for comparing the adaptation of 13 grassland Fabaceae species to different habitats, i.e. ecological niches. We measured a wide range of functional traits (root traits, leaf traits and whole plant traits in these species. Species phylogenetic and ecological distances were assessed from a species-level phylogenetic tree and species’ ecological indicator values, respectively. We demonstrated that differences in ecological niches between grassland Fabaceae species were related more to their hierarchical trait distances than to their phylogenetic distances. We showed that grassland Fabaceae functional traits tend to converge among species with the same ecological requirements. Species with acquisitive root strategies (thin roots, shallow root systems are competitive species adapted to non-stressful meadows, while conservative ones (coarse roots, deep root systems are able to tolerate stressful continental climates. In contrast, acquisitive species appeared to be able to tolerate low soil-P availability, while conservative ones need high P availability. Finally we highlight that traits converge along the ecological gradient, providing the assumption that species with similar root-trait values are better able to coexist, regardless of their phylogenetic distance.

  19. Distance labeling schemes for trees

    DEFF Research Database (Denmark)

    Alstrup, Stephen; Gørtz, Inge Li; Bistrup Halvorsen, Esben

    2016-01-01

    We consider distance labeling schemes for trees: given a tree with n nodes, label the nodes with binary strings such that, given the labels of any two nodes, one can determine, by looking only at the labels, the distance in the tree between the two nodes. A lower bound by Gavoille et al. [Gavoille...... variants such as, for example, small distances in trees [Alstrup et al., SODA, 2003]. We improve the known upper and lower bounds of exact distance labeling by showing that 1/4 log2(n) bits are needed and that 1/2 log2(n) bits are sufficient. We also give (1 + ε)-stretch labeling schemes using Theta......(log(n)) bits for constant ε> 0. (1 + ε)-stretch labeling schemes with polylogarithmic label size have previously been established for doubling dimension graphs by Talwar [Talwar, STOC, 2004]. In addition, we present matching upper and lower bounds for distance labeling for caterpillars, showing that labels...

  20. New Genetics

    Science.gov (United States)

    ... Home > Science Education > The New Genetics The New Genetics Living Laboratories Classroom Poster Order a Free Copy ... Piece to a Century-Old Evolutionary Puzzle Computing Genetics Model Organisms RNA Interference The New Genetics is ...

  1. The Distance Field Model and Distance Constrained MAP Adaptation Algorithm

    Institute of Scientific and Technical Information of China (English)

    YUPeng; WANGZuoying

    2003-01-01

    Spatial structure information, i.e., the rel-ative position information of phonetic states in the feature space, is long to be carefully researched yet. In this pa-per, a new model named “Distance Field” is proposed to describe the spatial structure information. Based on this model, a modified MAP adaptation algorithm named dis-tance constrained maximum a poateriori (DCMAP) is in-troduced. The distance field model gives large penalty when the spatial structure is destroyed. As a result the DCMAP reserves the spatial structure information in adaptation process. Experiments show the Distance Field Model improves the performance of MAP adapta-tion. Further results show DCMAP has strong cross-state estimation ability, which is used to train a well-performed speaker-dependent model by data from only part of pho-

  2. The Distance to M104

    CERN Document Server

    McQuinn, Kristen B W; Dolphin, Andrew E; Berg, Danielle; Kennicutt, Robert

    2016-01-01

    M104 (NGC 4594; the Sombrero galaxy) is a nearby, well-studied elliptical galaxy included in scores of surveys focused on understanding the details of galaxy evolution. Despite the importance of observations of M104, a consensus distance has not yet been established. Here, we use newly obtained Hubble Space Telescope optical imaging to measure the distance to M104 based on the tip of the red giant branch method. Our measurement yields the distance to M104 to be 9.55 +/- 0.13 +/- 0.31 Mpc equivalent to a distance modulus of 29.90 +/- 0.03 +/- 0.07 mag. Our distance is an improvement over previous results as we use a well-calibrated, stable distance indicator, precision photometry in a optimally selected field of view, and a Bayesian Maximum Likelihood technique that reduces measurement uncertainties. The most discrepant previous results are due to Tully-Fisher method distances, which are likely inappropriate for M104 given its peculiar morphology and structure. Our results are part of a larger program to measu...

  3. Reducing the distance in distance-caregiving by technology innovation

    Directory of Open Access Journals (Sweden)

    Lazelle E Benefield

    2007-07-01

    Full Text Available Lazelle E Benefield1, Cornelia Beck21College of Nursing, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA; 2Pat & Willard Walker Family Memory Research Center, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USAAbstract: Family caregivers are responsible for the home care of over 34 million older adults in the United States. For many, the elder family member lives more than an hour’s distance away. Distance caregiving is a growing alternative to more familiar models where: 1 the elder and the family caregiver(s may reside in the same household; or 2 the family caregiver may live nearby but not in the same household as the elder. The distance caregiving model involves elders and their family caregivers who live at some distance, defined as more than a 60-minute commute, from one another. Evidence suggests that distance caregiving is a distinct phenomenon, differs substantially from on-site family caregiving, and requires additional assistance to support the physical, social, and contextual dimensions of the caregiving process. Technology-based assists could virtually connect the caregiver and elder and provide strong support that addresses the elder’s physical, social, cognitive, and/or sensory impairments. Therefore, in today’s era of high technology, it is surprising that so few affordable innovations are being marketed for distance caregiving. This article addresses distance caregiving, proposes the use of technology innovation to support caregiving, and suggests a research agenda to better inform policy decisions related to the unique needs of this situation.Keywords: caregiving, family, distance, technology, elders

  4. Molecular evidence for long-distance colonization in an Indo-Pacific seahorse lineage

    Digital Repository Service at National Institute of Oceanography (India)

    Teske, P.R.; Hamilton, H.; Palsboll, P.J.; Choo, C.K.; Gabr, H.; Lourie, S.A.; Santos, M.; Sreepada, R.A.; Cherry, M.I.; Matthee, C.A.

    of relative population ages, tests for evidence of population expansion, pair-wise migration rates and divergence times, as well as relationships between genetic and geographic distances. The mtDNA data indicate that all populations have undergone recent...

  5. Genetic toxicology: web resources.

    Science.gov (United States)

    Young, Robert R

    2002-04-25

    Genetic toxicology is the scientific discipline dealing with the effects of chemical, physical and biological agents on the heredity of living organisms. The Internet offers a wide range of online digital resources for the field of Genetic Toxicology. The history of genetic toxicology and electronic data collections are reviewed. Web-based resources at US National Library of Medicine (NLM), including MEDLINE, PUBMED, Gateway, Entrez, and TOXNET, are discussed. Search strategies and Medical Subject Headings (MeSH) are reviewed in the context of genetic toxicology. The TOXNET group of databases are discussed with emphasis on those databases with genetic toxicology content including GENE-TOX, TOXLINE, Hazardous Substances Data Bank, Integrated Risk Information System, and Chemical Carcinogenesis Research Information System. Location of chemical information including chemical structure and linkage to health and regulatory information using CHEMIDPLUS at NLM and other databases is reviewed. Various government agencies have active genetic toxicology research programs or use genetic toxicology data to assist fulfilling the agency's mission. Online resources at the US Food and Drug Administration (FDA), the US Environmental Protection Agency (EPA), the National Institutes of Environmental Health Sciences, and the National Toxicology Program (NTP) are outlined. Much of the genetic toxicology for pharmaceuticals, industrial chemicals and pesticides that is performed in the world is regulatory-driven. Regulatory web resources are presented for the laws mandating testing, guidelines on study design, Good Laboratory Practice (GLP) regulations, and requirements for electronic data collection and reporting. The Internet provides a range of other supporting resources to the field of genetic toxicology. The web links for key professional societies and journals in genetic toxicology are listed. Distance education, educational media resources, and job placement services are also

  6. Distance Learning for Special Populations

    Science.gov (United States)

    Bates, Rodger A.

    2012-01-01

    Distance education strategies for remotely deployed, highly mobile, or institutionalized populations are reviewed and critiqued. Specifically, asynchronous, offline responses for special military units, Native Americans on remote reservations, prison populations and other geographically, temporally or technologically isolated niche populations are…

  7. ECONOMICS OF DISTANCE EDUCATION RECONSIDERED

    Directory of Open Access Journals (Sweden)

    Wolfram LAASER

    2008-07-01

    Full Text Available ABSTRACT According to Gartner a certain hype of e-Learning was followed by a downturn but eLearning will continue to be an important factor in learning scenarios. However the economic viability of e-learning projects will be questioned with more scrutiny than in earlier periods. Therefore it seems to be a good opportunity to see what can be learned from past experience in costing distance learning projects and what aspects are added by current attempts to measure economic efficiency. After reviewing early research about costing distance learning some more recent approaches will be discussed, such as eLearning ROI-calculators and the concept of total cost of ownership. Furthermore some microeconomic effects referring to localization of distance learning courses are outlined. Finally several unsolved issues in costing distance education are summarized.

  8. Distance Education in Technological Age

    Directory of Open Access Journals (Sweden)

    R .C. SHARMA

    2005-04-01

    Full Text Available Distance Education in Technological AgeRomesh Verma (Editor, New Delhi: Anmol Publications, 2005, ISBN 81-261-2210-2, pp. 419 Reviewed by R C SHARMARegional DirectorIndira Gandhi National Open University-INDIA The advancements in information and communication technologies have brought significant changes in the way the open and distance learning are provided to the learners. The impact of such changes is quite visible in both developed and developing countries. Switching over to online mode, joining hands with private initiatives and making a presence in foreign waters, are some of the hallmarks of the open and distance education (ODE institutions in developing countries. The compilation of twenty six essays on themes as applicable to ODE has resulted in the book, “Distance Education in Technological Age”. These essays follow a progressive style of narration, starting from describing conceptual framework of distance education, how the distance education was emerged on the global scene and in India, and then goes on to discuss emergence of online distance education and research aspects in ODE. The initial four chapters provide a detailed account of historical development and growth of distance education in India and State Open University and National Open University Model in India . Student support services are pivot to any distance education and much of its success depends on how well the support services are provided. These are discussed from national and international perspective. The issues of collaborative learning, learning on demand, life long learning, learning-unlearning and re-learning model and strategic alliances have also given due space by the authors. An assortment of technologies like communication technology, domestic technology, information technology, mass media and entertainment technology, media technology and educational technology give an idea of how these technologies are being adopted in the open universities. The study

  9. KNOWLEDGE DISTANCE IN INFORMATION SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Yuhua QIAN; Jiye LIANG; Chuangyin DANG; Feng WANG; Wei XU

    2007-01-01

    In this paper, we first introduce the concepts of knowledge closeness and knowledge distance for measuring the sameness and the difference among knowledge in an information system, respectively.The relationship between these two concepts is a strictly mutual complement relation. We then investigate some important properties of knowledge distance and perform experimental analyses on two public data sets, which show the presented measure appears to be well suited to characterize the nature of knowledge in an information system. Finally, we establish the relationship between the knowledge distance and knowledge granulation, which shows that two variants of the knowledge distance can also be used to construct the knowledge granulation. These results will be helpful for studying uncertainty in information systems.

  10. Graph distance for complex networks

    Science.gov (United States)

    Shimada, Yutaka; Hirata, Yoshito; Ikeguchi, Tohru; Aihara, Kazuyuki

    2016-10-01

    Networks are widely used as a tool for describing diverse real complex systems and have been successfully applied to many fields. The distance between networks is one of the most fundamental concepts for properly classifying real networks, detecting temporal changes in network structures, and effectively predicting their temporal evolution. However, this distance has rarely been discussed in the theory of complex networks. Here, we propose a graph distance between networks based on a Laplacian matrix that reflects the structural and dynamical properties of networked dynamical systems. Our results indicate that the Laplacian-based graph distance effectively quantifies the structural difference between complex networks. We further show that our approach successfully elucidates the temporal properties underlying temporal networks observed in the context of face-to-face human interactions.

  11. Are contemporary tourists consuming distance?

    DEFF Research Database (Denmark)

    Larsen, Gunvor Riber

    2012. Background The background for this research, which explores how tourists represent distance and whether or not distance can be said to be consumed by contemporary tourists, is the increasing leisure mobility of people. Travelling for the purpose of visiting friends and relatives is increasing...... of understanding mobility at a conceptual level, and distance matters to people's manifest mobility: how they travel and how far they travel are central elements of their movements. Therefore leisure mobility (indeed all mobility) is the activity of relating across distance, either through actual corporeal...... that is an inherent part of manifest mobility. Numerous definitions and conceptualisations of tourism have been discussed over the years, with MacCannell (1976) pioneering studies of tourism and leisure travel through to Lash and Urry's (1994) post tourist and Jansson's (2002) hyper-tourist. These definitions...

  12. Academy Distance Learning Tools (IRIS)

    Data.gov (United States)

    Department of Transportation — IRIS is a suite of front-end web applications utilizing a centralized back-end Oracle database. The system fully supports the FAA Academy's Distance Learning Program...

  13. Distance education: turf and technology.

    Science.gov (United States)

    Pickard, M R

    1992-07-01

    Distance learning fits with the mission and strategic plan of the University of Texas at Arlington. We believe these educational opportunities in nursing are highly desirable. The Board of Nurse Examiners for the State of Texas has approved this project and the Texas Higher Education Coordinating Board has approved it as a pilot project. The school will continue evaluation and creative problem-solving in the use of distance education.

  14. Categorical perception of tactile distance

    OpenAIRE

    Knight, F. L. C.; Longo, M. R.; Bremner, A.J.

    2014-01-01

    The tactile surface forms a continuous sheet covering the body. And yet, the perceived distance between two touches varies across stimulation sites. Perceived tactile distance is larger when stimuli cross over the wrist, compared to when both fall on either the hand or the forearm. This effect could reflect a categorical distortion of tactile space across body-part boundaries (in which stimuli crossing the wrist boundary are perceptually elongated) or may simply reflect a localised increased ...

  15. Categorical perception of tactile distance.

    Science.gov (United States)

    Knight, Frances Le Cornu; Longo, Matthew R; Bremner, Andrew J

    2014-05-01

    The tactile surface forms a continuous sheet covering the body. And yet, the perceived distance between two touches varies across stimulation sites. Perceived tactile distance is larger when stimuli cross over the wrist, compared to when both fall on either the hand or the forearm. This effect could reflect a categorical distortion of tactile space across body-part boundaries (in which stimuli crossing the wrist boundary are perceptually elongated) or may simply reflect a localised increased in acuity surrounding anatomical landmarks (in which stimuli near the wrist are perceptually elongated). We tested these two interpretations across two experiments, by comparing a well-documented bias to perceive mediolateral tactile distances across the forearm/hand as larger than proximodistal ones along the forearm/hand at three different sites (hand, wrist, and forearm). According to the 'categorical' interpretation, tactile distances should be elongated selectively in the proximodistal axis thus reducing the anisotropy. According to the 'localised acuity' interpretation, distances will be perceptually elongated in the vicinity of the wrist regardless of orientation, leading to increased overall size without affecting anisotropy. Consistent with the categorical account, we found a reduction in the magnitude of anisotropy at the wrist, with no evidence of a corresponding localised increase in precision. These findings demonstrate that we reference touch to a representation of the body that is categorically segmented into discrete parts, which consequently influences the perception of tactile distance.

  16. Center—Distance Continuous Probability Models and the Distance Measure

    Institute of Scientific and Technical Information of China (English)

    郑方; 吴文虎; 等

    1998-01-01

    In this paper,a new statistic model named Center-Distance Continuous Probability Model(CDCPM)for speech recognition is described,which is based on Center-Distance Normal(CDN)distribution.In a CDCPM,the probability transition matrix is omitted,and the observation probability density function(PDF)in each state is in the form of embedded multiple-model(EMM)based on the Nearest Neighbour rule.The experimental results on two giant real-world Chinese speech databases and a real-world continuous-manner 2000 phrase system show that this model is a powerful one.Also,a distance measure for CDPMs is proposed which is based on the Bayesian minimum classification error(MCE) discrimination.

  17. Long-distance effects of insertional mutagenesis.

    Directory of Open Access Journals (Sweden)

    Ruchi Singhal

    Full Text Available BACKGROUND: Most common systems of genetic engineering of mammalian cells are associated with insertional mutagenesis of the modified cells. Insertional mutagenesis is also a popular approach to generate random alterations for gene discovery projects. A better understanding of the interaction of the structural elements within an insertional mutagen and the ability of such elements to influence host genes at various distances away from the insertion site is a matter of considerable practical importance. METHODOLOGY/PRINCIPAL FINDINGS: We observed that, in the context of a lentiviral construct, a transcript, which is initiated at an internal CMV promoter/enhancer region and incorporates a splice donor site, is able to extend past a collinear viral LTR and trap exons of host genes, while the polyadenylation signal, which is naturally present in the LTR, is spliced out. Unexpectedly, when a vector, which utilizes this phenomenon, was used to produce mutants with elevated activity of NF-κB, we found mutants, which owed their phenotype to the effect of the insert on a gene located tens or even hundreds of kilobases away from the insertion site. This effect did not result from a CMV-driven transcript, but was sensitive to functional suppression of the insert. Interestingly, despite the long-distance effect, expression of loci most closely positioned to the insert appeared unaffected. CONCLUSIONS/SIGNIFICANCE: We concluded that a polyadenylation signal in a retroviral LTR, when occurring within an intron, is an inefficient barrier against the formation of a hybrid transcript, and that a vector containing a strong enhancer may selectively affect the function of genes far away from its insertion site. These phenomena have to be considered when experimental or therapeutic transduction is performed. In particular, the long-distance effects of insertional mutagenesis bring into question the relevance of the lists of disease-associated retroviral integration

  18. Conceptualizing Educational Research in Distance Education.

    Science.gov (United States)

    Watkins, Ryan; Schlosser, Charles

    2003-01-01

    Suggests a starting place for formal inquiry into distance education. Topics covered include: background on educational research and research on distance education; research paradigms that are applicable to distance education; subsystems of a distance education program; and a matrix for conceptualizing distance education research. (MES)

  19. Computing Distances between Probabilistic Automata

    Directory of Open Access Journals (Sweden)

    Mathieu Tracol

    2011-07-01

    Full Text Available We present relaxed notions of simulation and bisimulation on Probabilistic Automata (PA, that allow some error epsilon. When epsilon is zero we retrieve the usual notions of bisimulation and simulation on PAs. We give logical characterisations of these notions by choosing suitable logics which differ from the elementary ones, L with negation and L without negation, by the modal operator. Using flow networks, we show how to compute the relations in PTIME. This allows the definition of an efficiently computable non-discounted distance between the states of a PA. A natural modification of this distance is introduced, to obtain a discounted distance, which weakens the influence of long term transitions. We compare our notions of distance to others previously defined and illustrate our approach on various examples. We also show that our distance is not expansive with respect to process algebra operators. Although L without negation is a suitable logic to characterise epsilon-(bisimulation on deterministic PAs, it is not for general PAs; interestingly, we prove that it does characterise weaker notions, called a priori epsilon-(bisimulation, which we prove to be NP-difficult to decide.

  20. Distance sampling methods and applications

    CERN Document Server

    Buckland, S T; Marques, T A; Oedekoven, C S

    2015-01-01

    In this book, the authors cover the basic methods and advances within distance sampling that are most valuable to practitioners and in ecology more broadly. This is the fourth book dedicated to distance sampling. In the decade since the last book published, there have been a number of new developments. The intervening years have also shown which advances are of most use. This self-contained book covers topics from the previous publications, while also including recent developments in method, software and application. Distance sampling refers to a suite of methods, including line and point transect sampling, in which animal density or abundance is estimated from a sample of distances to detected individuals. The book illustrates these methods through case studies; data sets and computer code are supplied to readers through the book’s accompanying website.  Some of the case studies use the software Distance, while others use R code. The book is in three parts.  The first part addresses basic methods, the ...

  1. Individual differences in distance perception.

    Science.gov (United States)

    Jackson, Russell E

    2009-05-07

    Distance perception is among the most pervasive mental phenomena and the oldest research topics in behavioural science. However, we do not understand well the most pervasive finding of distance perception research, that of large individual differences. There are large individual differences in acrophobia (fear of heights), which we commonly assume consists of an abnormal fear of stimuli perceived normally. Evolved navigation theory (ENT) instead suggests that acrophobia consists of a more normal fear of stimuli perceived abnormally. ENT suggests that distance perception individual differences produce major components of acrophobia. Acrophobia tested over a broad range in the present study predicted large individual differences in distance estimation of surfaces that could produce falls. This fear of heights correlated positively with distance estimates of a vertical surface-even among non-acrophobic individuals at no risk of falling and without knowledge of being tested for acrophobia. Acrophobia score predicted magnitude of the descent illusion, which is thought to reflect the risk of falling. These data hold important implications in environmental navigation, clinical aetiology and the evolution of visual systems.

  2. Genetic algorithms

    Science.gov (United States)

    Wang, Lui; Bayer, Steven E.

    1991-01-01

    Genetic algorithms are mathematical, highly parallel, adaptive search procedures (i.e., problem solving methods) based loosely on the processes of natural genetics and Darwinian survival of the fittest. Basic genetic algorithms concepts are introduced, genetic algorithm applications are introduced, and results are presented from a project to develop a software tool that will enable the widespread use of genetic algorithm technology.

  3. Genetic Mapping

    Science.gov (United States)

    ... Fact Sheets Fact Sheets En Español: Mapeo Genético Genetic Mapping What is genetic mapping? How do researchers create ... genetic map? What are genetic markers? What is genetic mapping? Among the main goals of the Human Genome ...

  4. Asymmetric distances for binary embeddings.

    Science.gov (United States)

    Gordo, Albert; Perronnin, Florent; Gong, Yunchao; Lazebnik, Svetlana

    2014-01-01

    In large-scale query-by-example retrieval, embedding image signatures in a binary space offers two benefits: data compression and search efficiency. While most embedding algorithms binarize both query and database signatures, it has been noted that this is not strictly a requirement. Indeed, asymmetric schemes that binarize the database signatures but not the query still enjoy the same two benefits but may provide superior accuracy. In this work, we propose two general asymmetric distances that are applicable to a wide variety of embedding techniques including locality sensitive hashing (LSH), locality sensitive binary codes (LSBC), spectral hashing (SH), PCA embedding (PCAE), PCAE with random rotations (PCAE-RR), and PCAE with iterative quantization (PCAE-ITQ). We experiment on four public benchmarks containing up to 1M images and show that the proposed asymmetric distances consistently lead to large improvements over the symmetric Hamming distance for all binary embedding techniques.

  5. Ghost imaging with broad distance

    Institute of Scientific and Technical Information of China (English)

    段德洋; 张路; 杜少将; 夏云杰

    2015-01-01

    We present a scheme that is able to achieve the ghost imaging with broad distance. The physical nature of our scheme is that the different wavelength beams are separated in free space by an optical media according to the slow light or dispersion principle. Meanwhile, the equality of the optical distance of the two light arms is not violated. The photon correlation is achieved by the rotating ground glass plate (RGGP) and spatial light modulator (SLM), respectively. Our work shows that a monochromic ghost image can be obtained in the case of RGGP. More importantly, the position (or distance) of the object can be ascertained by the color of the image. Thus, the imaging and ranging processes are combined as one process for the first time to the best of our knowledge. In the case of SLM, we can obtain a colored image regardless of where the object is.

  6. Euclidean distance geometry an introduction

    CERN Document Server

    Liberti, Leo

    2017-01-01

    This textbook, the first of its kind, presents the fundamentals of distance geometry:  theory, useful methodologies for obtaining solutions, and real world applications. Concise proofs are given and step-by-step algorithms for solving fundamental problems efficiently and precisely are presented in Mathematica®, enabling the reader to experiment with concepts and methods as they are introduced. Descriptive graphics, examples, and problems, accompany the real gems of the text, namely the applications in visualization of graphs, localization of sensor networks, protein conformation from distance data, clock synchronization protocols, robotics, and control of unmanned underwater vehicles, to name several.  Aimed at intermediate undergraduates, beginning graduate students, researchers, and practitioners, the reader with a basic knowledge of linear algebra will gain an understanding of the basic theories of distance geometry and why they work in real life.

  7. Virtual bioinformatics distance learning suite*.

    Science.gov (United States)

    Tolvanen, Martti; Vihinen, Mauno

    2004-05-01

    Distance learning as a computer-aided concept allows students to take courses from anywhere at any time. In bioinformatics, computers are needed to collect, store, process, and analyze massive amounts of biological and biomedical data. We have applied the concept of distance learning in virtual bioinformatics to provide university course material over the Internet. Currently, we provide two fully computer-based courses, "Introduction to Bioinformatics" and "Bioinformatics in Functional Genomics." Here we will discuss the application of distance learning in bioinformatics training and our experiences gained during the 3 years that we have run the courses, with about 400 students from a number of universities. The courses are available at bioinf.uta.fi.

  8. The Distance Geometry of Music

    CERN Document Server

    Demaine, Erik D; Meijer, Henk; Rappaport, David; Taslakian, Perouz; Toussaint, Godfried T; Winograd, Terry; Wood, David R

    2007-01-01

    We demonstrate relationships between the classic Euclidean algorithm and many other fields of study, particularly in the context of music and distance geometry. Specifically, we show how the structure of the Euclidean algorithm defines a family of rhythms which encompass over forty timelines (\\emph{ostinatos}) from traditional world music. We prove that these \\emph{Euclidean rhythms} have the mathematical property that their onset patterns are distributed as evenly as possible: they maximize the sum of the Euclidean distances between all pairs of onsets, viewing onsets as points on a circle. Indeed, Euclidean rhythms are the unique rhythms that maximize this notion of \\emph{evenness}. We also show that essentially all Euclidean rhythms are \\emph{deep}: each distinct distance between onsets occurs with a unique multiplicity, and these multiplicies form an interval $1,2,...,k-1$. Finally, we characterize all deep rhythms, showing that they form a subclass of generated rhythms, which in turn proves a useful prop...

  9. Cultural interaction and biological distance in postclassic period Mexico.

    Science.gov (United States)

    Ragsdale, Corey S; Edgar, Heather J H

    2015-05-01

    Economic, political, and cultural relationships connected virtually every population throughout Mexico during Postclassic period (AD 900-1520). Much of what is known about population interaction in prehistoric Mexico is based on archaeological or ethnohistoric data. What is unclear, especially for the Postclassic period, is how these data correlate with biological population structure. We address this by assessing biological (phenotypic) distances among 28 samples based upon a comparison of dental morphology trait frequencies, which serve as a proxy for genetic variation, from 810 individuals. These distances were compared with models representing geographic and cultural relationships among the same groups. Results of Mantel and partial Mantel matrix correlation tests show that shared migration and trade are correlated with biological distances, but geographic distance is not. Trade and political interaction are also correlated with biological distance when combined in a single matrix. These results indicate that trade and political relationships affected population structure among Postclassic Mexican populations. We suggest that trade likely played a major role in shaping patterns of interaction between populations. This study also shows that the biological distance data support the migration histories described in ethnohistoric sources. © 2015 Wiley Periodicals, Inc.

  10. Adaptive Distance Protection for Microgrids

    DEFF Research Database (Denmark)

    Lin, Hengwei; Guerrero, Josep M.; Quintero, Juan Carlos Vasquez

    2015-01-01

    Due to the increasing penetration of distributed generation resources, more and more microgrids can be found in distribution systems. This paper proposes a phasor measurement unit based distance protection strategy for microgrids in distribution system. At the same time, transfer tripping scheme...... is adopted to accelerate the tripping speed of the relays on the weak lines. The protection methodology is tested on a mid-voltage microgrid network in Aalborg, Denmark. The results show that the adaptive distance protection methodology has good selectivity and sensitivity. What is more, this system also has...

  11. Genetic Counseling

    Science.gov (United States)

    Genetic counseling provides information and support to people who have, or may be at risk for, genetic disorders. A ... meets with you to discuss genetic risks. The counseling may be for yourself or a family member. ...

  12. Fast Exact Euclidean Distance (FEED) Transformation

    NARCIS (Netherlands)

    Schouten, Theo; Broek, van den Egon; Kittler, J.; Petrou, M.; Nixon, M.

    2004-01-01

    Fast Exact Euclidean Distance (FEED) transformation is introduced, starting from the inverse of the distance transformation. The prohibitive computational cost of a naive implementation of traditional Euclidean Distance Transformation, is tackled by three operations: restriction of both the number o

  13. Genetic landscapes GIS Toolbox: tools to map patterns of genetic divergence and diversity.

    Science.gov (United States)

    Vandergast, Amy G.; Perry, William M.; Lugo, Roberto V.; Hathaway, Stacie A.

    2011-01-01

    The Landscape Genetics GIS Toolbox contains tools that run in the Geographic Information System software, ArcGIS, to map genetic landscapes and to summarize multiple genetic landscapes as average and variance surfaces. These tools can be used to visualize the distribution of genetic diversity across geographic space and to study associations between patterns of genetic diversity and geographic features or other geo-referenced environmental data sets. Together, these tools create genetic landscape surfaces directly from tables containing genetic distance or diversity data and sample location coordinates, greatly reducing the complexity of building and analyzing these raster surfaces in a Geographic Information System.

  14. Distância genética entre linhagens avançadas de germoplasma de algodão com uso de marcadores de RAPD e microssatélites Genetic distance among advanced lineages of cotton germplasm using RAPD and microsatellite markers

    Directory of Open Access Journals (Sweden)

    Ivandilson Pessoa Pinto de Menezes

    2008-10-01

    Full Text Available O objetivo deste trabalho foi selecionar coeficientes de similaridade para serem aplicados a conjuntos de genótipos de algodoeiro com baixa diversidade genética. Analisou-se um conjunto de 65 linhagens e 4 cultivares de algodão, com marcadores de RAPD e SSR, e estimou-se a similaridade genética de acordo com sete coeficientes de similaridade: Coincidência Simples, Rogers & Tanimoto, Ochiai, Hamman, Jaccard, Dice e Russel & Rao. A adequação dos coeficientes ao conjunto de genótipos foi verificada por correlação entre as matrizes de distância, índice de consenso entre os dendrogramas e otimização de Tocher. As análises mostraram que o coeficiente de Russel e Rao foi divergente em relação aos demais e seu uso não é recomendável. Entre os parâmetros usados para avaliar a qualidade de informação de cada coeficiente, apenas o índice de consenso estabeleceu diferenças e os classificou em dois grupos: aquele em que a ausência simultânea é considerada e aquele em que ela é desconsiderada. Considerando-se a presença de apenas dois alelos microssatélites por loco e os maiores índices de consenso, os coeficientes de Coincidência Simples, Hamman e Rogers & Tanimoto devem ser preferidos, quando em conjuntos de genótipos de algodoeiro melhorados e com baixa diversidade.The objective of this work was to select similarity coefficients to be used among sets of cotton genotypes with low genetic diversity. Sixty-five lineages and four cotton cultivars were analyzed by RAPD and SSR markers; and the genetic similarity was estimated by seven similarity coefficients: Simple Matching, Rogers & Tanimoto, Ochiai, Hamman, Jaccard, Dice and Russel & Rao. The adequacy of the use of each coefficient to the collected data was verified by correlation between the distance matrices, the consensus index between the dendrograms and the Tocher's optimization method. The coefficient of Russel & Rao was the most divergent, and its use is not

  15. The Future of Distance Education.

    Science.gov (United States)

    Saba, Farhad

    2000-01-01

    Examines factors that will influence how distance education is practiced in the first few decades of this new century. Discusses developments in digital technology; the exponential growth of knowledge about the brain, as well as physiology, chemistry, and psychology of learning; the system relationship between individual learners and instructors;…

  16. Using Podcasts in Distance Education

    Science.gov (United States)

    Koppelman, Herman

    2013-01-01

    This paper discusses three possible ways of applying podcasts in distance education: podcasts of recordings of virtual classes, podcasts produced for specific pedagogical aims, and podcasts produced by external organizations. Through a survey we gained insight in the (until now limited) experiences of our distant students with podcasts, and also…

  17. Distance Education Instructional Model Applications.

    Science.gov (United States)

    Jackman, Diane H.; Swan, Michael K.

    1995-01-01

    A survey of graduate students involved in distance education on North Dakota State University's Interactive Video Network included 80 on campus and 13 off. The instructional models rated most effective were role playing, simulation, jurisprudential (Socratic method), memorization, synectics, and inquiry. Direct instruction was rated least…

  18. Distance, Lending Relationships, and Competition

    NARCIS (Netherlands)

    Degryse, H.A.; Ongena, S.

    2003-01-01

    A recent string of theoretical papers has highlighted the importance of geographical distance in explaining loan rates for small firms.Lenders located in the vicinity of small firms face significantly lower transportation and monitoring costs, and hence wield considerable market power, if competing

  19. Favourite distances in high dimensions

    CERN Document Server

    Swanepoel, Konrad J

    2011-01-01

    Let $S$ be a set of $n$ points in $d$-dimensional Euclidean space. Assign to each $x\\in S$ an arbitrary distance $r(x)>0$. Let $e_r(x,S)$ denote the number of points in $S$ at distance $r(x)$ from $x$. Avis, Erd\\"os and Pach (1988) introduced the extremal quantity $f_d(n)=\\max\\sum_{x\\in S}e_r(x,S)$, where the maximum is taken over all $n$-point sets $S$ in $d$-dimensional space and all assignments $r\\colon S\\to(0,\\infty)$ of distances. We give a quick derivation of the asymptotics of the error term of $f_d(n)$ using only the analogous asymptotics of the maximum number of unit distance pairs in a set of $n$ points, which improves on previous results of Avis, Erd\\"os and Pach (1988) and Erd\\"os and Pach (1990). Then we prove a stability result for $d\\geq 4$, asserting that if $(S,r)$ with $|S|=n$ satisfies $e_r(S)=f_d(n)-o(n^2)$, then, up to $o(n)$ points, $S$ is a Lenz construction with $r$ constant. Finally we use stability to show that for $n$ sufficiently large (depending on $d$) the pairs $(S,r)$ that atta...

  20. Lessons in Developing Distance Learning.

    Science.gov (United States)

    Gant, Lenora Peters

    1996-01-01

    Describes the use of video teletraining (VTT) for distance learning in the Department of Defense. Topics include planning and organizing the VTT facility, staff development, site facilitators, the necessity of protocol, instructional design and development strategies, student involvement and interactivity, and evaluation and assessment. (LRW)

  1. Communication Barriers in Distance Education

    Science.gov (United States)

    Isman, Aytekin; Dabaj, Fahme; Altinay, Fahriye; Altinay, Zehra

    2003-01-01

    Communication is a key concept as being the major tool for people in order to satisfy their needs. It is an activity which refers as process and effective communication requires qualified communication with the elimination of communication barriers. As it is known, distance education is a new trend by following contemporary facilities and tools…

  2. Distance Learning: Untried and Untrue

    Science.gov (United States)

    Halfond, Jay A.

    2010-01-01

    G. K. Chesterton famously once said: "Christianity has not been tried and found wanting; it has been found difficult and not tried." This, the author believes, applies to distance learning as well. There is far too much self-congratulatory hyperbole about the growth and pervasiveness of online learning--which exaggerates reality and overlooks the…

  3. Curriculum Control in Distance Education.

    Science.gov (United States)

    Chesterton, Paul

    1985-01-01

    The nature of distance education is to shift the locus of curriculum control toward the institution and its staff and away from the students. This imposes a responsibility on the institution to examine and evaluate the values and assumptions underlying the decision-making and the implications of the patterns of control that emerge. (Author/MSE)

  4. Distance, Lending Relationships and Competition

    NARCIS (Netherlands)

    Degryse, H.A.; Ongena, S.

    2002-01-01

    A recent string of theoretical papers highlights the importance of geographical distance in explaining pricing and availability of loans to small firms.Lenders located in the vicinity of small firms have significantly lower monitoring and transaction costs, and hence considerable market power if com

  5. On Maximum Lee Distance Codes

    OpenAIRE

    Alderson, Tim L.; Svenja Huntemann

    2013-01-01

    Singleton-type upper bounds on the minimum Lee distance of general (not necessarily linear) Lee codes over ℤq are discussed. Two bounds known for linear codes are shown to also hold in the general case, and several new bounds are established. Codes meeting these bounds are investigated and in some cases characterised.

  6. Video Surveillance using Distance Maps

    NARCIS (Netherlands)

    Schouten, Theo E.; Kuppens, Harco C.; Broek, van den Egon L.; Kehtarnavaz, Nasser; Laplante, Phillip A.

    2006-01-01

    Human vigilance is limited; hence, automatic motion and distance detection is one of the central issues in video surveillance. Hereby, many aspects are of importance, this paper specially addresses: efficiency, achieving real-time performance, accuracy, and robustness against various noise factors.

  7. Gesture Interaction at a Distance

    NARCIS (Netherlands)

    Fikkert, F.W.

    2010-01-01

    The aim of this work is to explore, from a perspective of human behavior, which gestures are suited to control large display surfaces from a short distance away; why that is so; and, equally important, how such an interface can be made a reality. A well-known example of the type of interface that is

  8. The Perception of Ideological Distance

    NARCIS (Netherlands)

    Granberg, Donald; Brown, Thad A.

    1992-01-01

    Data from national election studies in Britain, the Netherlands, Sweden, and the U.S. were analyzed to test hypotheses concerning the perception of ideological distance between parties and candidates. The first hypothesis, derived from Sherif's social judgment theory and Heider's balance theory, was

  9. Video surveillance using distance maps

    NARCIS (Netherlands)

    Schouten, Theo E.; Kuppens, Harco C.; van den Broek, Egon; Kehtarnavaz, Nasser; Laplante, Phillip A,

    2006-01-01

    Human vigilance is limited; hence, automatic motion and distance detection is one of the central issues in video surveillance. Hereby, many aspects are of importance, this paper specially addresses: efficiency, achieving real-time performance, accuracy, and robustness against various noise factors.

  10. Genetic drift and the population history of the Irish travellers.

    Science.gov (United States)

    Relethford, John H; Crawford, Michael H

    2013-02-01

    The Irish Travellers are an itinerant group in Ireland that has been socially isolated. Two hypotheses have been proposed concerning the genetic origin of the Travellers: (1) they are genetically related to Roma populations in Europe that share a nomadic lifestyle or (2) they are of Irish origin, and genetic differences from the rest of Ireland reflect genetic drift. These hypotheses were tested using data on 33 alleles from 12 red blood cell polymorphism loci. Comparison with other European, Roma, and Indian populations shows that the Travellers are genetically distinct from the Roma and Indian populations and most genetically similar to Ireland, in agreement with earlier genetic analyses of the Travellers. However, the Travellers are still genetically distinct from other Irish populations, which could reflect some external gene flow and/or the action of genetic drift in a small group that was descended from a small number of founders. In order to test the drift hypothesis, we analyzed genetic distances comparing the Travellers to four geographic regions in Ireland. These distances were then compared with adjusted distances that account for differential genetic drift using a method developed by Relethford (Hum Biol 68 (1996) 29-44). The unadjusted distances show the genetic distinctiveness of the Travellers. After adjustment for the expected effects of genetic drift, the Travellers are equidistant from the other Irish samples, showing their Irish origins and population history. The observed genetic differences are thus a reflection of genetic drift, and there is no evidence of any external gene flow.

  11. A Streaming Distance Transform Algorithm for Neighborhood-Sequence Distances

    Directory of Open Access Journals (Sweden)

    Nicolas Normand

    2014-09-01

    Full Text Available We describe an algorithm that computes a “translated” 2D Neighborhood-Sequence Distance Transform (DT using a look up table approach. It requires a single raster scan of the input image and produces one line of output for every line of input. The neighborhood sequence is specified either by providing one period of some integer periodic sequence or by providing the rate of appearance of neighborhoods. The full algorithm optionally derives the regular (centered DT from the “translated” DT, providing the result image on-the-fly, with a minimal delay, before the input image is fully processed. Its efficiency can benefit all applications that use neighborhood- sequence distances, particularly when pipelined processing architectures are involved, or when the size of objects in the source image is limited.

  12. Effective Teaching in Distance Education. ERIC Digest.

    Science.gov (United States)

    Mielke, Dan

    Distance education is an alternative method for delivering academic course work to students unable to attend traditional campus-based classes. This Digest presents information on the many forms of distance education and keys to successful teaching with distance education. Distance education is a method of education in which the learner is…

  13. The intractability of computing the Hamming distance

    NARCIS (Netherlands)

    Manthey, Bodo; Reischuk, Rüdiger

    2005-01-01

    Given a string x and a language L, the Hamming distance of x to L is the minimum Hamming distance of x to any string in L. The edit distance of a string to a language is analogously defined. First, we prove that there is a language in $AC^0$ such that both Hamming and edit distance to this language

  14. Distance Education Use in Rural Schools

    Science.gov (United States)

    Hannum, Wallace H.; Irvin, Matthew J.; Banks, Jonathan B.; Farmer, Thomas W.

    2009-01-01

    A national survey of rural school systems in the United States was conducted to determine the extent to which distance education is being utilized by rural schools, the technologies used, the curriculum areas impacted, the perceived needs for distance education, their satisfaction with distance education, and the barriers to distance education…

  15. History and Heritage in Distance Education

    Science.gov (United States)

    Anderson, Bill; Simpson, Mary

    2012-01-01

    Distance education's history is a tremendous resource for all involved in distance education. Some aspects of that history provide enduring touchstones for present distance educators, creating a heritage that should not be overlooked as distance education continues to develop and expand. In this article we draw on the concept of generational…

  16. Determining distances using asteroseismic methods

    CERN Document Server

    Aguirre, V Silva; Basu, S; Campante, T L; Chaplin, W J; Huber, D; Miglio, A; Serenelli, A M; WG#1, KASC

    2012-01-01

    Asteroseismology has been extremely successful in determining the properties of stars in different evolutionary stages with a remarkable level of precision. However, to fully exploit its potential, robust methods for estimating stellar parameters are required and independent verification of the results is needed. In this talk, I present a new technique developed to obtain stellar properties by coupling asteroseismic analysis with the InfraRed Flux Method. Using two global seismic observables and multi-band photometry, the technique determines masses, radii, effective temperatures, bolometric fluxes, and thus distances for field stars in a self-consistent manner. Applying our method to a sample of solar-like oscillators in the {\\it Kepler} field that have accurate {\\it Hipparcos} parallaxes, we find agreement in our distance determinations to better than 5%. Comparison with measurements of spectroscopic effective temperatures and interferometric radii also validate our results, and show that our technique can ...

  17. Managerial Distance and Virtual Ownership

    DEFF Research Database (Denmark)

    Hansmann, Henry; Thomsen, Steen

    Industrial foundations are autonomous nonprofit entities that own and control one or more conventional business firms. These foundations are common in Northern Europe, where they own a number of internationally prominent companies. Previous studies have indicated, surprisingly, that companies con......, but corporate governance and fiduciary behavior more generally....... on differences among the industrial foundations themselves. We work with a rich data set comprising 113 foundation-owned Danish companies over the period 2003-2008. We focus in particular on a composite structural factor that we term “managerial distance.” We propose this as a measure of the extent to which......-seeking outside owners of the company. Consistent with this hypothesis, our empirical analysis shows a positive, significant, and robust association between managerial distance and the economic performance of foundation owned companies. The findings appear to illuminate not just foundation governance...

  18. Theological Librarianship from a Distance

    Directory of Open Access Journals (Sweden)

    Melody Diehl Detar

    2015-08-01

    Full Text Available This essay examines distance theological librarianship and the field’s suitability for remote librarians. A brief introduction to the landscape of online programs in theological education is followed by an overview of virtual librarianship and how theological librarians may serve students while working from a distance themselves. The essay then describes a method for initiating a remote librarian position in a theological library context, and then reviews the steps of determining whether remote work is feasible and desirable at an institution, approaching leadership with a plan, setting up a trial remote work period, and assessing its success. Particular emphasis is given to communication expectations, modes of virtual reference and instruction, campus committee service and meaningful ways of remaining part of the campus community.

  19. Moral distance in dictator games

    Directory of Open Access Journals (Sweden)

    Fernando Aguiar

    2008-04-01

    Full Text Available We perform an experimental investigation using a dictator game in which individuals must make a moral decision --- to give or not to give an amount of money to poor people in the Third World. A questionnaire in which the subjects are asked about the reasons for their decision shows that, at least in this case, moral motivations carry a heavy weight in the decision: the majority of dictators give the money for reasons of a consequentialist nature. Based on the results presented here and of other analogous experiments, we conclude that dicator behavior can be understood in terms of moral distance rather than social distance and that it systematically deviates from the egoism assumption in economic models and game theory. %extit{JEL}: A13, C72, C91

  20. Students’ Role in Distance Learning

    OpenAIRE

    Beers Fägersten, Kristy

    2008-01-01

    1. IntroductionMuch of the support that students have in a traditional classroom is absent in a distance learning course. In the traditional classroom, the learner is together with his or her classmates and the teacher; learning is socially embedded. Students can talk to each other and may learn from each other as they go through the learning process together. They also witness the teacher’s expression of the knowledge firsthand. The class participants communicate to each other not ...

  1. Distance probes of dark energy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, A. G.; Padmanabhan, N.; Aldering, G.; Allen, S. W.; Baltay, C.; Cahn, R. N.; D’Andrea, C. B.; Dalal, N.; Dawson, K. S.; Denney, K. D.; Eisenstein, D. J.; Finley, D. A.; Freedman, W. L.; Ho, S.; Holz, D. E.; Kasen, D.; Kent, S. M.; Kessler, R.; Kuhlmann, S.; Linder, E. V.; Martini, P.; Nugent, P. E.; Perlmutter, S.; Peterson, B. M.; Riess, A. G.; Rubin, D.; Sako, M.; Suntzeff, N. V.; Suzuki, N.; Thomas, R. C.; Wood-Vasey, W. M.; Woosley, S. E.

    2015-03-01

    This document presents the results from the Distances subgroup of the Cosmic Frontier Community Planning Study (Snowmass 2013). We summarize the current state of the field as well as future prospects and challenges. In addition to the established probes using Type Ia supernovae and baryon acoustic oscillations, we also consider prospective methods based on clusters, active galactic nuclei, gravitational wave sirens and strong lensing time delays.

  2. Hardware Euclidean Distance Transform Implementation

    Institute of Scientific and Technical Information of China (English)

    XIE Ying-hua; ZENG Pei-feng; TANG Li-ping

    2004-01-01

    Based on an efficient algorithm of Euclidean distance transform for binary images, a circuit of O(N2) size is proposed. With in-place calculation, both the intermediate data storing and the result output use the same memory with the input data. This reduces the amount of memory largely. By replacing multipliers with counters, comparators, and adders, the circuit size is further reduced and its calculation speed is improved also.

  3. Distance Probes of Dark Energy

    CERN Document Server

    Kim, A; Aldering, G; Allen, S; Baltay, C; Cahn, R; D'Andrea, C; Dalal, N; Dawson, K; Denney, K; Eisenstein, D; Finley, D; Freedman, W; Ho, S; Holz, D; Kent, A; Kasen, D; Kessler, R; Kuhlmann, S; Linder, E; Martini, P; Nugent, P; Perlmutter, S; Peterson, B; Riess, A; Rubin, D; Sako, M; Suntzeff, N; Suzuki, N; Thomas, R; Wood-Vasey, W M; Woosley, S

    2013-01-01

    This document presents the results from the Distances subgroup of the Cosmic Frontier Community Planning Study (Snowmass 2013). We summarize the current state of the field as well as future prospects and challenges. In addition to the established probes using Type IA supernovae and baryon acoustic oscillations, we also consider prospective methods based on clusters, active galactic nuclei, gravitational wave sirens and strong lensing time delays.

  4. Distance effects in electrochemical micromachining

    OpenAIRE

    2016-01-01

    Considering exponential dependence of currents on double-layer voltage and the feedback effect of the electrolyte resistance, a distance effect in electrochemical micromachining is found, namely that both time constant and double-layer voltage depend on the separation of electrodes. The double-layer voltage is the real voltage used in processing. Under DC voltage, the apparent voltages between two electrodes are constant for different separations, but the real voltages change with the separat...

  5. The Magnetotail at Lunar Distance

    Science.gov (United States)

    Sibeck, D. G.

    2015-12-01

    This presentation reviews some of the single-point observations of the magnetotail at lunar distances made by ALSEP, Explorer 33, 35, ISEE-3, and Geotail that form the framework for interpreting more recent dual-spacecraft ARTEMIS observations. Earth's distant magnetotail flaps, twists, and flattens in response to variations in the solar wind flow direction and interplanetary magnetic field (IMF) orientation. It may even disappear leaving nothing more than a wake during strongly northward IMF orientations. Standing slow mode expansion fans provide for a gradual transition between magnetotail lobe and magnetosheath plasma and magnetic field parameters. The distant neutral line may at times reside at lunar distances, creating jets of sunward-streaming plasma within the cislunar plasma sheet and layers of streaming energetic particles on its boundaries. Reconnection at near-Earth neutral lines releases antisunward-moving plasmoids that transit lunar distances, briefly expanding the diameter of the plasma sheet and magnetotail. Taken as a whole, the distant magnetotail is a fascinating plasma laboratory and a region of great important to the magnetosphere.

  6. Support Services for Distance Education

    Directory of Open Access Journals (Sweden)

    Sandra Frieden

    1999-01-01

    Full Text Available The creation and operation of a distance education support infrastructure requires the collaboration of virtually all administrative departments whose activities deal with students and faculty, and all participating academic departments. Implementation can build on where the institution is and design service-oriented strategies that strengthen institutional support and commitment. Issues to address include planning, faculty issues and concerns, policies and guidelines, approval processes, scheduling, training, publicity, information-line operations, informational materials, orientation and registration processes, class coordination and support, testing, evaluations, receive site management, partnerships, budgets, staffing, library and e-mail support, and different delivery modes (microwave, compressed video, radio, satellite, public television/cable, video tape and online. The process is ongoing and increasingly participative as various groups on campus begin to get involved with distance education activities. The distance education unit must continuously examine and revise its processes and procedures to maintain the academic integrity and service excellence of its programs. It’s a daunting prospect to revise the way things have been done for many years, but each department has an opportunity to respond to new ways of serving and reaching students.

  7. Fingerprinting with Minimum Distance Decoding

    CERN Document Server

    Lin, Shih-Chun; Gamal, Hesham El

    2007-01-01

    This work adopts an information theoretic framework for the design of collusion-resistant coding/decoding schemes for digital fingerprinting. More specifically, the minimum distance decision rule is used to identify 1 out of t pirates. Achievable rates, under this detection rule, are characterized in two distinct scenarios. First, we consider the averaging attack where a random coding argument is used to show that the rate 1/2 is achievable with t=2 pirates. Our study is then extended to the general case of arbitrary $t$ highlighting the underlying complexity-performance tradeoff. Overall, these results establish the significant performance gains offered by minimum distance decoding as compared to other approaches based on orthogonal codes and correlation detectors. In the second scenario, we characterize the achievable rates, with minimum distance decoding, under any collusion attack that satisfies the marking assumption. For t=2 pirates, we show that the rate $1-H(0.25)\\approx 0.188$ is achievable using an ...

  8. Editorial ~ Global Diversity of Distance Education

    OpenAIRE

    2001-01-01

    In a panel presentation at the recent International Council for Open and Distance Education (ICDE) world conference in Dusseldorf, Germany, I had the opportunity to explain the unique role and mission of International Review of Research in Open and Distance Learning (IRRODL) vis – vis our more established sister journals: Open Praxis, Open Learning, Journal of Distance Education, Distance Education, and American Journal of Distance Education. Although all of these journals share a common comm...

  9. The Monge distance between quantum states

    Energy Technology Data Exchange (ETDEWEB)

    Zyczkowski, Karol [Institute for Plasma Research, University of Maryland, College Park, MD (United States); Slomczynski, Wojciech [Instytut Matematyki, Uniwersytet Jagiellonski, Cracow (Poland)

    1998-11-13

    We define a metric in the space of quantum states taking the Monge distance between corresponding Husimi distributions (Q-functions). This quantity fulfils the axioms of a metric and satisfies the following semiclassical property: the distance between two coherent states is equal to the Euclidean distance between corresponding points in the classical phase space. We compute analytically distances between certain states (coherent, squeezed, Fock and thermal) and discuss a scheme for numerical computation of Monge distance for two arbitrary quantum states. (author)

  10. GENETIC DIVERSITY AND ECO-GEOGRAPHICAL DISTRIBUTION ...

    African Journals Online (AJOL)

    ACSS

    3Department of Plant Biology and Biodiversity Management, Addis Ababa University, Ethiopia ... Allelic frequency based inter-species genetic distance analysis, showed wider .... taxonomy, evolution and origin of the species ...... Age International (P) Limited, New Delhi, India ... Integrated analysis environment for genetic.

  11. Mattig's relation and dynamical distance indicators

    CERN Document Server

    Teerikorpi, Pekka

    2016-01-01

    We discuss how the redshift (Mattig) method in Friedmann cosmology relates to dynamical distance indicators based on Newton's gravity (Teerikorpi 2011). It belongs to the class of indicators where the relevant length inside the system is the distance itself (in this case the proper metric distance). As the Friedmann model has Newtonian analogy, its use to infer distances has instructive similarities to classical dynamical distance indicators. In view of the theoretical exact linear distance-velocity law, we emphasize that it is conceptually correct to derive the cosmological distance via the route: redshift (primarily observed) --> space expansion velocity (not directly observed) --> metric distance (physical length in "cm"). Important properties of the proper metric distance are summarized.

  12. An overview on distance and pseudo distance functions and their applications

    Institute of Scientific and Technical Information of China (English)

    ZHU Xiangyang; DING Han; ZHONG Binglin; XIONG Youlun

    2003-01-01

    The fast and accurate collision detection and distance calculation between geometric models is fundamental in robotics, manufacturing and computer-simulated environments. This paper surveys the state of the art in the theory and algorithms of distance and pseudo distance functions between convex sets. An overview on the existing results, including fast algorithms for distance calculation, definitions and properties of various pseudo distance functions (the J-function, the growth distance, and the pseudo minimum translational distance), is presented. The distance and pseudo distance functions are versatile in a wide range of areas. Their applications in robot motion planning, grasp analysis/synthesis, form error evaluation, and engineering optimization is demonstrated.

  13. Distance Measurement Solves Astrophysical Mysteries

    Science.gov (United States)

    2003-08-01

    Location, location, and location. The old real-estate adage about what's really important proved applicable to astrophysics as astronomers used the sharp radio "vision" of the National Science Foundation's Very Long Baseline Array (VLBA) to pinpoint the distance to a pulsar. Their accurate distance measurement then resolved a dispute over the pulsar's birthplace, allowed the astronomers to determine the size of its neutron star and possibly solve a mystery about cosmic rays. "Getting an accurate distance to this pulsar gave us a real bonanza," said Walter Brisken, of the National Radio Astronomy Observatory (NRAO) in Socorro, NM. Monogem Ring The Monogem Ring, in X-Ray Image by ROSAT satellite CREDIT: Max-Planck Institute, American Astronomical Society (Click on Image for Larger Version) The pulsar, called PSR B0656+14, is in the constellation Gemini, and appears to be near the center of a circular supernova remnant that straddles Gemini and its neighboring constellation, Monoceros, and is thus called the Monogem Ring. Since pulsars are superdense, spinning neutron stars left over when a massive star explodes as a supernova, it was logical to assume that the Monogem Ring, the shell of debris from a supernova explosion, was the remnant of the blast that created the pulsar. However, astronomers using indirect methods of determining the distance to the pulsar had concluded that it was nearly 2500 light-years from Earth. On the other hand, the supernova remnant was determined to be only about 1000 light-years from Earth. It seemed unlikely that the two were related, but instead appeared nearby in the sky purely by a chance juxtaposition. Brisken and his colleagues used the VLBA to make precise measurements of the sky position of PSR B0656+14 from 2000 to 2002. They were able to detect the slight offset in the object's apparent position when viewed from opposite sides of Earth's orbit around the Sun. This effect, called parallax, provides a direct measurement of

  14. Variable Distance Angular Symbology Reader

    Science.gov (United States)

    Schramm, Harry F., Jr. (Inventor); Corder, Eric L. (Inventor)

    2006-01-01

    A variable distance angular symbology, reader utilizes at least one light source to direct light through a beam splitter and onto a target. A target may be angled relative to the impinging light beam up to and maybe even greater than 45deg. A reflected beam from the target passes through the beam splitter and is preferably directed 90deg relative to the light source through a telecentric lens to a scanner which records an image of the target such as a direct part marking code.

  15. Genetic Structure of Acetobacter diazotrophicus Populations and Identification of a New Genetically Distant Group

    OpenAIRE

    Caballero-Mellado, J.; Fuentes-Ramirez, L. E.; Reis, V. M.; Martinez-Romero, E.

    1995-01-01

    A total of 55 isolates of Acetobacter diazotrophicus recovered from diverse sucrose-rich host plants and from mealybugs associated with sugarcane plants were characterized by the electrophoretic mobilities of 12 metabolic enzymes. We identified seven different electrophoretic types (ETs), six of which are closely related within a genetic distance of 0.195 and exhibit high DNA-DNA homology. The seventh ET was largely divergent, separated at a genetic distance of 0.53, and had only 54% DNA homo...

  16. Anxiety and Resistance in Distance Learning

    Directory of Open Access Journals (Sweden)

    Nazime Tuncay

    2010-06-01

    Full Text Available The purpose of this study was to investigate students' anxiety and resistance towards learning through distance education.Specifically, the study sought answers to the following questions: -What are the reasons of students not choosing distancelearning courses? -Which symptoms of anxiety, if any, do distance learner’s exhibit towards distance learning? Does genderhave any significant relationships with distance learners' perception of factors that affect their anxiety and resistance? A totalof 120 distance education students in Near East University were observed and 96 of them were interviewed. Computer anxiety,language anxiety, social anxiety were observed to be among the reasons of students’ resistance to distance learning.

  17. A note on the path interval distance.

    Science.gov (United States)

    Coons, Jane Ivy; Rusinko, Joseph

    2016-06-01

    The path interval distance accounts for global congruence between locally incongruent trees. We show that the path interval distance provides a lower bound for the nearest neighbor interchange distance. In contrast to the Robinson-Foulds distance, random pairs of trees are unlikely to be maximally distant from one another under the path interval distance. These features indicate that the path interval distance should play a role in phylogenomics where the comparison of trees on a fixed set of taxa is becoming increasingly important.

  18. Lightweight Distance Bounding Protocol against Relay Attacks

    Science.gov (United States)

    Kim, Jin Seok; Cho, Kookrae; Yum, Dae Hyun; Hong, Sung Je; Lee, Pil Joong

    Traditional authentication protocols are based on cryptographic techniques to achieve identity verification. Distance bounding protocols are an enhanced type of authentication protocol built upon both signal traversal time measurement and cryptographic techniques to accomplish distance verification as well as identity verification. A distance bounding protocol is usually designed to defend against the relay attack and the distance fraud attack. As there are applications to which the distance fraud attack is not a serious threat, we propose a streamlined distance bounding protocol that focuses on the relay attack. The proposed protocol is more efficient than previous protocols and has a low false acceptance rate under the relay attack.

  19. Genetic Disorders

    Science.gov (United States)

    ... This can cause a medical condition called a genetic disorder. You can inherit a gene mutation from ... during your lifetime. There are three types of genetic disorders: Single-gene disorders, where a mutation affects ...

  20. Genetic modification and genetic determinism.

    Science.gov (United States)

    Resnik, David B; Vorhaus, Daniel B

    2006-06-26

    In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism. Since these strong deterministic assumptions are false, the arguments against genetic modification, which assume and depend upon these assumptions, are therefore unsound. Serious discussion of the morality of genetic modification, and the development of sound science policy, should be driven by arguments that address the actual consequences of genetic modification for individuals and society, not by ones propped up by false or misleading biological assumptions.

  1. Imaging Genetics

    Science.gov (United States)

    Munoz, Karen E.; Hyde, Luke W.; Hariri, Ahmad R.

    2009-01-01

    Imaging genetics is an experimental strategy that integrates molecular genetics and neuroimaging technology to examine biological mechanisms that mediate differences in behavior and the risks for psychiatric disorder. The basic principles in imaging genetics and the development of the field are discussed.

  2. Genetic principles.

    Science.gov (United States)

    Abuelo, D

    1987-01-01

    The author discusses the basic principles of genetics, including the classification of genetic disorders and a consideration of the rules and mechanisms of inheritance. The most common pitfalls in clinical genetic diagnosis are described, with emphasis on the problem of the negative or misleading family history.

  3. Imaging Genetics

    Science.gov (United States)

    Munoz, Karen E.; Hyde, Luke W.; Hariri, Ahmad R.

    2009-01-01

    Imaging genetics is an experimental strategy that integrates molecular genetics and neuroimaging technology to examine biological mechanisms that mediate differences in behavior and the risks for psychiatric disorder. The basic principles in imaging genetics and the development of the field are discussed.

  4. Three-Distance Sequences with Three Symbols

    OpenAIRE

    SAKAMOTO, Kuniko

    2003-01-01

    We will show that every $3$ dimensional cutting sequence is a three-distance sequence, and there are uncountable many periodic or aperiodic three-distance sequences (with $3$-symbols) which are not $3$ dimensional cutting sequences.

  5. A Cognitively Grounded Measure of Pronunciation Distance

    NARCIS (Netherlands)

    Wieling, M.; Nerbonne, J.; Bloem, J.; Gooskens, C.; Heeringa, W.; Baayen, R.H.

    2014-01-01

    In this study we develop pronunciation distances based on naive discriminative learning (NDL). Measures of pronunciation distance are used in several subfields of linguistics, including psycholinguistics, dialectology and typology. In contrast to the commonly used Levenshtein algorithm, NDL is groun

  6. Modeling seed dispersal distances: implications for transgenic Pinus taeda.

    Science.gov (United States)

    Williams, Claire G; LaDeau, Shannon L; Oren, Ram; Katul, Gabriel G

    2006-02-01

    Predicting forest-tree seed dispersal across a landscape is useful for estimating gene flow from genetically engineered (GE) or transgenic trees. The question of biocontainment has yet to be resolved, although field-trial permits for transgenic forest trees are on the rise. Most current field trials in the United States occur in the Southeast where Pinus taeda L., an indigenous species, is the major timber commodity. Seed dispersal distances were simulated using a model where the major determinants were: (1) forest canopy height at seed release, (2) terminal velocity of the seeds, (3) absolute seed release, and (4) turbulent-flow statistics, all of which were measured or determined within a P. taeda plantation established from seeds collected from wild forest-tree stands at the Duke Forest near Durham, North Carolina, USA. In plantations aged 16 and 25 years our model results showed that most of the seeds fell within local-neighborhood dispersal distances, with estimates ranging from 0.05 to 0.14 km from the source. A fraction of seeds was uplifted above the forest canopy and moved via the long-distance dispersal (LDD) process as far as 11.9-33.7 km. Out of 10(5) seeds produced per hectare per year, roughly 440 seeds were predicted to be uplifted by vertical eddies above the forest canopy and transported via LDD. Of these, 70 seeds/ha traveled distances in excess of 1 km from the source, a distance too great to serve as a biocontainment zone. The probability of LDD occurrence of transgenic conifer seeds at distances exceeding 1 km approached 100%.

  7. THE INFLUENCE OF WOMEN ON DISTANCE EDUCATION

    OpenAIRE

    2014-01-01

    The impact of distance education on women has been significant. Distance education has been a viable means for helping women reach their educational ambitions. Over the last 40 years distance education has increased the ease of access and control over study time. With geographical and time barriers removed, women in particular were able to add the role of student to their list of responsibilities. Women have defeated educational barriers through educational opportunities presented by distance...

  8. Distance-based classification of keystroke dynamics

    Science.gov (United States)

    Tran Nguyen, Ngoc

    2016-07-01

    This paper uses the keystroke dynamics in user authentication. The relationship between the distance metrics and the data template, for the first time, was analyzed and new distance based algorithm for keystroke dynamics classification was proposed. The results of the experiments on the CMU keystroke dynamics benchmark dataset1 were evaluated with an equal error rate of 0.0614. The classifiers using the proposed distance metric outperform existing top performing keystroke dynamics classifiers which use traditional distance metrics.

  9. Genetic modification and genetic determinism

    OpenAIRE

    Vorhaus Daniel B; Resnik David B

    2006-01-01

    Abstract In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism. Since these strong deterministic assumptions are false, the arguments against genetic modification, which assume and depend upon these assumptions, are therefore unsound....

  10. Distance effects in electrochemical micromachining

    Science.gov (United States)

    Xu, Lizhong; Pan, Yue; Zhao, Chuanjun

    2016-09-01

    Considering exponential dependence of currents on double-layer voltage and the feedback effect of the electrolyte resistance, a distance effect in electrochemical micromachining is found, namely that both time constant and double-layer voltage depend on the separation of electrodes. The double-layer voltage is the real voltage used in processing. Under DC voltage, the apparent voltages between two electrodes are constant for different separations, but the real voltages change with the separations. Small separations exert substantial effects on the real voltages. Accordingly, a DC-voltage small-separation electrochemical micromachining technique was proposed. The double-layer voltage drops sharply as the small separation increases. Thus, the electrochemical reactions are confined to electrode regions in very close proximity even under DC voltage. The machining precision can be significantly enhanced by reducing the voltage and separation between electrodes. With this technique, the machining of conducting materials with submicrometre precision was achieved.

  11. Normalized Compression Distance of Multiples

    CERN Document Server

    Cohen, Andrew R

    2012-01-01

    Normalized compression distance (NCD) is a parameter-free similarity measure based on compression. The NCD between pairs of objects is not sufficient for all applications. We propose an NCD of finite multisets (multiples) of objacts that is metric and is better for many applications. Previously, attempts to obtain such an NCD failed. We use the theoretical notion of Kolmogorov complexity that for practical purposes is approximated from above by the length of the compressed version of the file involved, using a real-world compression program. We applied the new NCD for multiples to retinal progenitor cell questions that were earlier treated with the pairwise NCD. Here we get significantly better results. We also applied the NCD for multiples to synthetic time sequence data. The preliminary results are as good as nearest neighbor Euclidean classifier.

  12. Time delay and distance measurement

    Science.gov (United States)

    Abshire, James B. (Inventor); Sun, Xiaoli (Inventor)

    2011-01-01

    A method for measuring time delay and distance may include providing an electromagnetic radiation carrier frequency and modulating one or more of amplitude, phase, frequency, polarization, and pointing angle of the carrier frequency with a return to zero (RZ) pseudo random noise (PN) code. The RZ PN code may have a constant bit period and a pulse duration that is less than the bit period. A receiver may detect the electromagnetic radiation and calculate the scattering profile versus time (or range) by computing a cross correlation function between the recorded received signal and a three-state RZ PN code kernel in the receiver. The method also may be used for pulse delay time (i.e., PPM) communications.

  13. Elasticity of Long Distance Travelling

    DEFF Research Database (Denmark)

    Knudsen, Mette Aagaard

    2011-01-01

    With data from the Danish expenditure survey for 12 years 1996 through 2007, this study analyses household expenditures for long distance travelling. Household expenditures are examined at two levels of aggregation having the general expenditures on transportation and leisure relative to five other...... aggregated commodities at the highest level, and the specific expenditures on plane tickets and travel packages at the lowest level. The Almost Ideal Demand System is applied to determine the relationship between expenditures on transportation and leisure and all other purchased non-durables within...... packages has higher income elasticity of demand than plane tickets but also higher than transportation and leisure in general. The findings within price sensitiveness are not as sufficient estimated, but the model results indicate that travel packages is far more price elastic than plane tickets which...

  14. Perspectives of Research on Distance Education.

    Science.gov (United States)

    Holmberg, Borje

    The history of research on distance education was studied. Major research done on distance education in such diverse areas as the United States, Venezuela, and Europe was analyzed. It was discovered that the earliest attempts to develop theories of distance education were mainly concerned with identifying its very concept. Like most educational…

  15. Rough Way for Academics: Distance Education

    Science.gov (United States)

    Gursul, Fatih

    2010-01-01

    This study aims to compare the academics' perceptions about face to face and distance education, beside finding out the contributions of distance education to them, difficulties they experience in synchronous and asynchronous distance education environments and suggestions for possible solutions of the existing problems. The sample consists of 52…

  16. Global continuation for distance geometry problems

    Energy Technology Data Exchange (ETDEWEB)

    More, J.J.; Wu, Zhijun

    1995-03-01

    Distance geometry problems arise in the interpretation of NMR data and in the determination of protein structure. The authors formulate the distance geometry problem as a global minimization problem with special structure, and show the global smoothing techniques and a continuation approach for global optimization can be used to determine solutions of distance geometry problems with a nearly 100% probability of success.

  17. Analysing designed experiments in distance sampling

    Science.gov (United States)

    Stephen T. Buckland; Robin E. Russell; Brett G. Dickson; Victoria A. Saab; Donal N. Gorman; William M. Block

    2009-01-01

    Distance sampling is a survey technique for estimating the abundance or density of wild animal populations. Detection probabilities of animals inherently differ by species, age class, habitats, or sex. By incorporating the change in an observer's ability to detect a particular class of animals as a function of distance, distance sampling leads to density estimates...

  18. Phylogeny and geometry of languages from normalized Levenshtein distance

    CERN Document Server

    Serva, Maurizio

    2011-01-01

    The idea that the distance among pairs of languages can be evaluated from lexical differences seems to have its roots in the work of the French explorer Dumont D'Urville. He collected comparative words lists of various languages during his voyages aboard the Astrolabe from 1826 to 1829 and, in his work about the geographical division of the Pacific, he proposed a method to measure the degree of relation between languages. The method used by the modern lexicostatistics, developed by Morris Swadesh in the 1950s, measures distances from the percentage of shared cognates, which are words with a common historical origin. The weak point of this method is that subjective judgment plays a relevant role. Recently, we have proposed a new automated method which is motivated by the analogy with genetics. The new approach avoids any subjectivity and results can be easily replicated by other scholars. The distance between two languages is defined by considering a renormalized Levenshtein distance between pair of words with...

  19. A virtual computer lab for distance biomedical technology education

    Science.gov (United States)

    Locatis, Craig; Vega, Anibal; Bhagwat, Medha; Liu, Wei-Li; Conde, Jose

    2008-01-01

    Background The National Library of Medicine's National Center for Biotechnology Information offers mini-courses which entail applying concepts in biochemistry and genetics to search genomics databases and other information sources. They are highly interactive and involve use of 3D molecular visualization software that can be computationally taxing. Methods Methods were devised to offer the courses at a distance so as to provide as much functionality of a computer lab as possible, the venue where they are normally taught. The methods, which can be employed with varied videoconferencing technology and desktop sharing software, were used to deliver mini-courses at a distance in pilot applications where students could see demonstrations by the instructor and the instructor could observe and interact with students working at their remote desktops. Results Student ratings of the learning experience and comments to open ended questions were similar to those when the courses are offered face to face. The real time interaction and the instructor's ability to access student desktops from a distance in order to provide individual assistance and feedback were considered invaluable. Conclusion The technologies and methods mimic much of the functionality of computer labs and may be usefully applied in any context where content changes frequently, training needs to be offered on complex computer applications at a distance in real time, and where it is necessary for the instructor to monitor students as they work. PMID:18366629

  20. Geographic distance affects dispersal of the patchy distributed greater long-tailed hamster (Tscherskia triton).

    Science.gov (United States)

    Xue, Huiliang; Zhong, Min; Xu, Jinhui; Xu, Laixiang

    2014-01-01

    Dispersal is a fundamental process in ecology influencing the genetic structure and the viability of populations. Understanding how variable factors influence the dispersal of the population is becoming an important question in animal ecology. To date, geographic distance and geographic barriers are often considered as main factors impacting dispersal, but their effects are variable depending on different conditions. In general, geographic barriers affect more significantly than geographic distance on dispersal. In rapidly expanding populations, however, geographic barriers have less effect on dispersal than geographic distance. The effects of both geographic distance and geographic barriers in low-density populations with patchy distributions are poorly understood. By using a panel of 10 microsatellite loci we investigated the genetic structure of three patchy-distributed populations of the Greater long-tailed hamster (Tscherskia triton) from Raoyang, Guan and Shunyi counties of the North China Plain. The results showed that (i) high genetic diversity and differentiation exist in three geographic populations with patchy distributions; (ii) gene flow occurs among these three populations with physical barriers of Beijing city and Hutuo River, which potentially restricted the dispersal of the animal; (iii) the gene flow is negatively correlated with the geographic distance, while the genetic distance shows the positive correlation. Our results suggest that the effect of the physical barriers is conditional-dependent, including barrier capacity or individual potentially dispersal ability. Geographic distance also acts as an important factor affecting dispersal for the patchy distributed geographic populations. So, gene flow is effective, even at relatively long distances, in balancing the effect of geographic barrier in this study.

  1. Genetic variation of Porphyra yezoensis by using AFLP1

    Institute of Scientific and Technical Information of China (English)

    Rui Yang; Biqian Liu; Qijun Luo; Yajun Wang; Jiamei Bao

    2003-01-01

    Genetic variation of 11 lines of Porphyra yezoensis from the coastline of Kagoshima ofJapan, Qingdao, Nantong, Putuo and Nanji Islands of China were studied by using amplified fragmentlength polymorphism (AFLP). 778 bands were obtained with AFLP analysis of 16 primer combina-tions, among which 15 were unique, about 98.07% were polymorphic. The AFLP data showed thatthe closest genetic distance was 0.180 between two Kagoshima samples, and the farthest one was 0.397between Kagoshima No. 1 and Nantong No. 9 line. The genetic distance showed that the variation waswithin the inner species scope. Neighbor-joining cluster and UPGMA cluster indicated that samples fromKagoshima and Qingdao were with high similarity and either with the samples of Nantong, Putuo andNanji Islands. P. yezoensis in China shared high genetic diversity, and the genetic distance showed posi-tive correlation with the geographic distance.

  2. From language identification to language distance

    Science.gov (United States)

    Gamallo, Pablo; Pichel, José Ramom; Alegria, Iñaki

    2017-10-01

    In this paper, we define two quantitative distances to measure how far apart two languages are. The distance measure that we have identified as more accurate is based on the perplexity of n-gram models extracted from text corpora. An experiment to compare forty-four European languages has been performed. For this purpose, we computed the distances for all the possible language pairs and built a network whose nodes are languages and edges are distances. The network we have built on the basis of linguistic distances represents the current map of similarities and divergences among the main languages of Europe.

  3. Continuity Properties of Distances for Markov Processes

    DEFF Research Database (Denmark)

    Jaeger, Manfred; Mao, Hua; Larsen, Kim Guldstrand

    2014-01-01

    In this paper we investigate distance functions on finite state Markov processes that measure the behavioural similarity of non-bisimilar processes. We consider both probabilistic bisimilarity metrics, and trace-based distances derived from standard Lp and Kullback-Leibler distances. Two desirable...... continuity properties for such distances are identified. We then establish a number of results that show that these two properties are in conflict, and not simultaneously fulfilled by any of our candidate natural distance functions. An impossibility result is derived that explains to some extent...

  4. Kinematic Distance of Galactic Planetary Nebulae

    CERN Document Server

    Yang, A Y; Zhu, H; Leahy, D A; Wu, D

    2016-01-01

    We construct \\HI~absorption spectra for 18 planetary nebulae (PNe) and their background sources using the data from the International Galactic Plane Survey. We estimate the kinematic distances of these PNe, among which 15 objects' kinematic distances are obtained for the first time. The distance uncertainties of 13 PNe range from 10% to 50%, which is a significant improvement with uncertainties of a factor two or three smaller than most of previous distance measurements. We confirm that PN G030.2-00.1 is not a PN because of its large distance found here.

  5. Experimental Population Genetics in the Introductory Genetics Laboratory Using "Drosophila" as a Model Organism

    Science.gov (United States)

    Johnson, Ronald; Kennon, Tillman

    2009-01-01

    Hypotheses of population genetics are derived and tested by students in the introductory genetics laboratory classroom as they explore the effects of biotic variables (physical traits of fruit flies) and abiotic variables (island size and distance) on fruit fly populations. In addition to this hypothesis-driven experiment, the development of…

  6. Experimental Population Genetics in the Introductory Genetics Laboratory Using "Drosophila" as a Model Organism

    Science.gov (United States)

    Johnson, Ronald; Kennon, Tillman

    2009-01-01

    Hypotheses of population genetics are derived and tested by students in the introductory genetics laboratory classroom as they explore the effects of biotic variables (physical traits of fruit flies) and abiotic variables (island size and distance) on fruit fly populations. In addition to this hypothesis-driven experiment, the development of…

  7. Learner characteristics involved in distance learning

    Energy Technology Data Exchange (ETDEWEB)

    Cernicek, A.T.; Hahn, H.A.

    1991-01-01

    Distance learning represents a strategy for leveraging resources to solve educational and training needs. Although many distance learning programs have been developed, lessons learned regarding differences between distance learning and traditional education with respect to learner characteristics have not been well documented. Therefore, we conducted a survey of 20 distance learning professionals. The questionnaire was distributed to experts attending the second Distance Learning Conference sponsored by Los Alamos National Laboratory. This survey not only acquired demographic information from each of the respondents but also identified important distance learning student characteristics. Significant distance learner characteristics, which were revealed statistically and which influence the effectiveness of distance learning, include the following: reading level, student autonomy, and self-motivation. Distance learning cannot become a more useful and effective method of instruction without identifying and recognizing learner characteristics. It will be important to consider these characteristics when designing all distance learning courses. This paper will report specific survey findings and their implications for developing distance learning courses. 9 refs., 6 tabs.

  8. Critical Points in Distance Learning System

    Directory of Open Access Journals (Sweden)

    Airina Savickaitė

    2013-08-01

    Full Text Available Purpose – This article presents the results of distance learning system analysis, i.e. the critical elements of the distance learning system. The critical points of distance learning are a part of distance education online environment interactivity/community process model. The most important is the fact that the critical point is associated with distance learning participants. Design/methodology/approach – Comparative review of articles and analysis of distance learning module. Findings – A modern man is a lifelong learner and distance learning is a way to be a modern person. The focus on a learner and feedback is the most important thing of learning distance system. Also, attention should be paid to the lecture-appropriate knowledge and ability to convey information. Distance system adaptation is the way to improve the learner’s learning outcomes. Research limitations/implications – Different learning disciplines and learning methods may have different critical points. Practical implications – The information of analysis could be important for both lecturers and students, who studies distance education systems. There are familiar critical points which may deteriorate the quality of learning. Originality/value – The study sought to develop remote systems for applications in order to improve the quality of knowledge. Keywords: distance learning, process model, critical points. Research type: review of literature and general overview.

  9. Distance Education at Silesian University of Technology

    Directory of Open Access Journals (Sweden)

    Piotr Klosowski

    2008-12-01

    Full Text Available This paper presents Distance Learning Platform used by Silesian University of Technology. Distance Learning Platform is based on modular object-oriented dynamic learning environment, represents LMS (Learning Management Systems technology, a software package designed to help educators create quality online courses. Currently on Distance Learning Platform at Silesian University of Technology are available over 520 online courses created for students of twelve University's faculties. Number of Distance Learning Platform users exceeds 12000. Distance Learning Platform works as typically asynchronous e-learning service, but in the future more synchronous e-learning services will be added. Distance Learning Platform has great potential to create a successful elearning experience by providing a plethora of excellent tools that can be used to enhance conventional classroom instruction, in hybrid courses, or any distance learning arrangements.

  10. Distance Education at Silesian University of Technology

    Directory of Open Access Journals (Sweden)

    Piotr Klosowski

    2008-12-01

    Full Text Available This paper presents Distance Learning Platform used by Silesian University of Technology. Distance Learning Platform is based on modular object-oriented dynamic learning environment, represents LMS (Learning Management Systems technology, a software package designed to help educators create quality online courses. Currently on Distance Learning Platform at Silesian University of Technology are available over 520 online courses created for students of twelve University's faculties. Number of Distance Learning Platform users exceeds 12000. Distance Learning Platform works as typically asynchronous e-learning service, but in the future more synchronous e-learning services will be added. Distance Learning Platform has great potential to create a successful elearning experience by providing a plethora of excellent tools that can be used to enhance conventional classroom instruction, in hybrid courses, or any distance learning arrangements.

  11. Correlation Analysis Between Heterosis and Genetic Distance Evaluated by Genome-Wide SNP Chip inBrassica napus%利用全基因组SNP芯片分析油菜遗传距离与杂种优势的关系

    Institute of Scientific and Technical Information of China (English)

    桑世飞; 王会; 梅德圣; 刘佳; 付丽; 王军; 汪文祥; 胡琼

    2015-01-01

    Objective] To investigate the feasibility of heterosis prediction by single nucleotide polymorphism (SNP) markers in rapeseed, the 60K SNP chip covering the whole genome ofBrassica napus was used to estimate the genetic distance (GD) of elite parental lines ofB. napus, and the correlation between GD and heterosis was analyzed for the guidance of hybrid development of rapeseed.[Method] Forty-six F1 hybrids were produced using six maintainer lines (1019B, 1055B, 6098B, 8908B, 6019B and ZS11B) and eight restorer lines (R1, R2, R3, R6, R9, R10, R11 and OR1) of Polima cytoplasmic male sterility (CMS) in an incomplete diallel cross design. All the parents and F1s were grown in three different ecological conditions which are located in Wuhan, Guiyang, and Chaohu. Ten yield-related traits including plant height (PH), branch height (BH), number of effective primary branches (NEPB), silique density (SD), effective length of main inflorescence (ELMI), number of effective siliques on main inflorescence (ESMI), number of effective siliques per plant (ESPP), seed per silique (SPS), 1 000-seed weight (TSW) and yield per plant (YPP) were investigated for mid-parent heterosis and high-parent heterosis. The 14 parental lines were genotyped by 60K SNP chip ofBrassicas. GD based on SNP genotyping was estimated with MEGA5.0 software, and cluster analysis was carried out using unweighted pair group method arithmetic averages (UPGMA) method. Correlation analysis between GD and heterosis was conducted by SAS9.1 statistical analysis software.[Result]There were 40 201 loci selected from 52 157 SNP loci as being effective for genetic distance calculation and cluster analysis after quality determination. GDs of the 14 parental lines ranged from 0.1883 to 0.8811, with an average of 0.5217. The GD between 6098B and 6019B was the smallest and that between ZS11B and R6 was the largest. The parental lines were divided into four groups, with six maintainers in one big group, four restorer lines R2

  12. Ocean currents help explain population genetic structure

    Science.gov (United States)

    White, Crow; Selkoe, Kimberly A.; Watson, James; Siegel, David A.; Zacherl, Danielle C.; Toonen, Robert J.

    2010-01-01

    Management and conservation can be greatly informed by considering explicitly how environmental factors influence population genetic structure. Using simulated larval dispersal estimates based on ocean current observations, we demonstrate how explicit consideration of frequency of exchange of larvae among sites via ocean advection can fundamentally change the interpretation of empirical population genetic structuring as compared with conventional spatial genetic analyses. Both frequency of larval exchange and empirical genetic difference were uncorrelated with Euclidean distance between sites. When transformed into relative oceanographic distances and integrated into a genetic isolation-by-distance framework, however, the frequency of larval exchange explained nearly 50 per cent of the variance in empirical genetic differences among sites over scales of tens of kilometres. Explanatory power was strongest when we considered effects of multiple generations of larval dispersal via intermediary locations on the long-term probability of exchange between sites. Our results uncover meaningful spatial patterning to population genetic structuring that corresponds with ocean circulation. This study advances our ability to interpret population structure from complex genetic data characteristic of high gene flow species, validates recent advances in oceanographic approaches for assessing larval dispersal and represents a novel approach to characterize population connectivity at small spatial scales germane to conservation and fisheries management. PMID:20133354

  13. Genetic barcodes

    Energy Technology Data Exchange (ETDEWEB)

    Weier, Heinz -Ulrich G

    2015-08-04

    Herein are described multicolor FISH probe sets termed "genetic barcodes" targeting several cancer or disease-related loci to assess gene rearrangements and copy number changes in tumor cells. Two, three or more different fluorophores are used to detect the genetic barcode sections thus permitting unique labeling and multilocus analysis in individual cell nuclei. Gene specific barcodes can be generated and combined to provide both numerical and structural genetic information for these and other pertinent disease associated genes.

  14. Open and Distance Learning Today. Routledge Studies in Distance Education Series.

    Science.gov (United States)

    Lockwood, Fred, Ed.

    This book contains the following papers on open and distance learning today: "Preface" (Daniel); "Big Bang Theory in Distance Education" (Hawkridge); "Practical Agenda for Theorists of Distance Education" (Perraton); "Trends, Directions and Needs: A View from Developing Countries" (Koul); "American Distance Education" (Moore); "Creating the…

  15. Long-Distance Free Fall

    Science.gov (United States)

    Gallant, Joseph

    1999-04-01

    One of the goals of physics education is to instill a sense of wonder in our students. We hope our natural curiosity will rub off on them and that they will apply the critical thinking skills we teach them to other aspects of their lives outside the classroom. As an example of this, consider the situation described in Milton's epic poem ``Paradise Lost''. Milton wrote that when the devil was cast out of heaven, he fell for nine days before landing in hell. In Milton's universe, hell is a separate place from Earth, but many people place hell at the center of the Earth. Based on these ideas, we can apply Newton's laws of motion to calculate the distance from heaven to Earth. This exercise is an example of the kind of intellectual exercise a physicist (or a physics student) might carry out when confronted with such information. We apply the basic principles of physics to a situation described in work of literature while making no attempt to validate or refute any philosophy, theology or ideology.

  16. Giant Sparks at Cosmological Distances?

    CERN Document Server

    Kulkarni, S R; Neill, J D; Zheng, Z; Juric, M

    2014-01-01

    [Abridged] Millisecond duration bright radio pulses in the 1.4-GHz band and with inferred dispersion measures (DM) well in excess of Galactic values have been reported by Lorimer et al. and Thornton et al.. The all-sky rate of these events is large, ~10^4 per day above ~1 Jy. To add to the mystery there now exists "Perytons'' -- also pulsed and dispersed sources but most certainly of local (artificial or atmospheric) origin. The suggested models now range from sources originating in the Earth's atmosphere, in stellar coronae, in other galaxies and at even cosmological distances. Using a series of physically motivated assumptions combined with the observed properties of these bursts, we explore possible constraints on sites or processes that can account for such high DMs. In our analysis, we focus on the first such reported event by Lorimer et al.: a 30 Jy, 5-ms duration burst with a dispersion measure of 375 cm^-3 pc and exhibiting a steep frequency-dependent pulse width (hereafter dubbed as the Sparker). Ass...

  17. The redshift-distance relation.

    Science.gov (United States)

    Segal, I E

    1993-06-01

    Key predictions of the Hubble law are inconsistent with direct observations on equitable complete samples of extragalactic sources in the optical, infrared, and x-ray wave bands-e.g., the predicted dispersion in apparent magnitude is persistently greatly in excess of its observed value, precluding an explanation via hypothetical perturbations or irregularities. In contrast, the predictions of the Lundmark (homogeneous quadratic) law are consistent with the observations. The Lundmark law moreover predicts the deviations between Hubble law predictions and observation with statistical consistency, while the Hubble law provides no explanation for the close fit of the Lundmark law. The flux-redshift law F [symbol, see text] (1 + z)/z appears consistent with observations on equitable complete samples in the entire observed redshift range, when due account is taken of flux limits by an optimal statistical method. Under the theoretical assumption that space is a fixed sphere, as in the Einstein universe, this law implies the redshift-distance relation z = tan2(r/2R), where R is the radius of the spherical space. This relation coincides with the prediction of chronometric cosmology, which estimates R as 160 +/- 40 Mpc (1 parsec = 3.09 x 10(16) m) from the proper motion to redshift relation of superluminal sources. Tangential aspects, including statistical methodology, fundamental physical theory, bright cluster galaxy samples, and proposed luminosity evolution, are briefly considered.

  18. THE GOULD'S BELT DISTANCE SURVEY

    Directory of Open Access Journals (Sweden)

    L. Loinard

    2011-01-01

    Full Text Available Observaciones que utilizan la interferometría de muy larga línea de base (VLBI por sus siglas en ingl´es pueden proveer la posición de radiofuentes compactas con una precisión del orden de 50 micro-segundos de arco. Esto es suficiente para medir la paralaje trigonométrica y los movimientos propios de cualquier objeto localizado hasta 500 pc del Sol con una precisión mejor que unos porcientos. Por ser magnéticamente activas, las estrellas jóvenes a menudo emiten emisión radio compacta detectable usando técnicas VLBI. Aquí, mostraremos cómo observaciones VLBI ya han restringido la distancia a las regiones de formación estelar cercanas más frecuentemente estudiadas (Tauro, Ofiuco, Orión, etc. y han empezado a revelar su estructura y su cinemática interna. Luego, describiremos un gran proyecto (llamado The Gould's Belt Distance Survey diseñado para proveer una vista detallada de la formación estelar en la vecindad Solar, usando observaciones VLBI.

  19. Distance-weighted city growth.

    Science.gov (United States)

    Rybski, Diego; García Cantú Ros, Anselmo; Kropp, Jürgen P

    2013-04-01

    Urban agglomerations exhibit complex emergent features of which Zipf's law, i.e., a power-law size distribution, and fractality may be regarded as the most prominent ones. We propose a simplistic model for the generation of citylike structures which is solely based on the assumption that growth is more likely to take place close to inhabited space. The model involves one parameter which is an exponent determining how strongly the attraction decays with the distance. In addition, the model is run iteratively so that existing clusters can grow (together) and new ones can emerge. The model is capable of reproducing the size distribution and the fractality of the boundary of the largest cluster. Although the power-law distribution depends on both, the imposed exponent and the iteration, the fractality seems to be independent of the former and only depends on the latter. Analyzing land-cover data, we estimate the parameter-value γ≈2.5 for Paris and its surroundings.

  20. Considering reefscape configuration and composition in biophysical models advance seascape genetics

    National Research Council Canada - National Science Library

    Simon Van Wynsberge; Serge Andréfouët; Nabila Gaertner-Mazouni; Josina Tiavouane; Daphné Grulois; Jérôme Lefèvre; Malin L Pinsky; Cécile Fauvelot

    2017-01-01

    Previous seascape genetics studies have emphasized the role of ocean currents and geographic distances to explain the genetic structure of marine species, but the role of benthic habitat has been more rarely considered...

  1. Genetic modification and genetic determinism

    Directory of Open Access Journals (Sweden)

    Vorhaus Daniel B

    2006-06-01

    Full Text Available Abstract In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism. Since these strong deterministic assumptions are false, the arguments against genetic modification, which assume and depend upon these assumptions, are therefore unsound. Serious discussion of the morality of genetic modification, and the development of sound science policy, should be driven by arguments that address the actual consequences of genetic modification for individuals and society, not by ones propped up by false or misleading biological assumptions.

  2. Robotic laboratory for distance education

    Science.gov (United States)

    Luciano, Sarah C.; Kost, Alan R.

    2016-09-01

    This project involves the construction of a remote-controlled laboratory experiment that can be accessed by online students. The project addresses a need to provide a laboratory experience for students who are taking online courses to be able to provide an in-class experience. The chosen task for the remote user is an optical engineering experiment, specifically aligning a spatial filter. We instrument the physical laboratory set up in Tucson, AZ at the University of Arizona. The hardware in the spatial filter experiment is augmented by motors and cameras to allow the user to remotely control the hardware. The user interacts with a software on their computer, which communicates with a server via Internet connection to the host computer in the Optics Laboratory at the University of Arizona. Our final overall system is comprised of several subsystems. These are the optical experiment set-up, which is a spatial filter experiment; the mechanical subsystem, which interfaces the motors with the micrometers to move the optical hardware; the electrical subsystem, which allows for the electrical communications from the remote computer to the host computer to the hardware; and finally the software subsystem, which is the means by which messages are communicated throughout the system. The goal of the project is to convey as much of an in-lab experience as possible by allowing the user to directly manipulate hardware and receive visual feedback in real-time. Thus, the remote user is able to learn important concepts from this particular experiment and is able to connect theory to the physical world by actually seeing the outcome of a procedure. The latter is a learning experience that is often lost with distance learning and is one that this project hopes to provide.

  3. Genetic structure of Rajaka caste and affinities with other caste populations of Andhra Pradesh, India.

    Science.gov (United States)

    Parvatheesam, C; Babu, B V; Babu, M C

    1997-01-01

    The present study gives an account of the genetic structure in terms of distribution of a few genetic markers, viz., A1A2B0, Rh(D), G6PD deficiency and haemoglobin among the Rajaka caste population of Andhra Pradesh, India. The genetic relationships of the Rajaka caste with other Andhra caste populations were investigated in terms of genetic distance, i.e., Sq B (mn) of Balakrishnan and Sanghvi. Relatively lesser distance was established between the Rajaka and two Panchama castes. Also, the pattern of genetic distance corroborates the hierarchical order of the Hindu varna system.

  4. Genetic Engineering

    Science.gov (United States)

    Phillips, John

    1973-01-01

    Presents a review of genetic engineering, in which the genotypes of plants and animals (including human genotypes) may be manipulated for the benefit of the human species. Discusses associated problems and solutions and provides an extensive bibliography of literature relating to genetic engineering. (JR)

  5. Genetic Counseling

    Science.gov (United States)

    ... for certain types of genetic conditions (such as Down syndrome) in the baby if mother-to-be is 35 years of age or more, or is concerned at any age about her chances of having a child with a genetic condition To learn about the ...

  6. Distance and Cable Length Measurement System

    Directory of Open Access Journals (Sweden)

    Jonay Toledo

    2009-12-01

    Full Text Available A simple, economic and successful design for distance and cable length detection is presented. The measurement system is based on the continuous repetition of a pulse that endlessly travels along the distance to be detected. There is a pulse repeater at both ends of the distance or cable to be measured. The endless repetition of the pulse generates a frequency that varies almost inversely with the distance to be measured. The resolution and distance or cable length range could be adjusted by varying the repetition time delay introduced at both ends and the measurement time. With this design a distance can be measured with centimeter resolution using electronic system with microsecond resolution, simplifying classical time of flight designs which require electronics with picosecond resolution. This design was also applied to position measurement.

  7. Distance and Cable Length Measurement System

    Science.gov (United States)

    Hernández, Sergio Elias; Acosta, Leopoldo; Toledo, Jonay

    2009-01-01

    A simple, economic and successful design for distance and cable length detection is presented. The measurement system is based on the continuous repetition of a pulse that endlessly travels along the distance to be detected. There is a pulse repeater at both ends of the distance or cable to be measured. The endless repetition of the pulse generates a frequency that varies almost inversely with the distance to be measured. The resolution and distance or cable length range could be adjusted by varying the repetition time delay introduced at both ends and the measurement time. With this design a distance can be measured with centimeter resolution using electronic system with microsecond resolution, simplifying classical time of flight designs which require electronics with picosecond resolution. This design was also applied to position measurement. PMID:22303169

  8. The Distance to the Draco Cloud

    CERN Document Server

    Gladders, M D; Burns, C R; Attard, A; Casey, M P; Hamilton, D; Mallén-Ornelas, G; Karr, J L; Poirier, S M; Sawicki, M; Barrientos, L F; Mochnacki, S W; Gladders, Michael D.; Burns, Christopher R.; Hamilton, Devon; Mallén-Ornelas, Gabriela; Poirier, Sara M.; Sawicki, Marcin; Mochnacki, Stefan W.

    1998-01-01

    The understanding of the nature of intermediate and high velocity gas in the Milky Way is hampered by a paucity of distance estimates to individual clouds. A project has been started at the David Dunlap Observatory to address this lack of distance measures by observing early-type stars along the line of sight towards these clouds and searching for sodium doublet absorption at the clouds' systemic velocities. Distances to foreground stars (no absorption) and background stars (with absorption) are estimated from spectroscopic parallax, and thus the distance to the bracketed cloud is estimated. In this Letter, we present the first result from this ongoing project, a measurement of the distance to the Draco Cloud, which is the most studied of the intermediate velocity clouds. The result presented here is the first distance bracket which tightly constrains the position of the Draco Cloud. We briefly describe our target selection and observing methodology, and then demonstrate absorption at the velocity of the Drac...

  9. Genetic Romanticism

    DEFF Research Database (Denmark)

    Tupasela, Aaro

    2016-01-01

    . This article compares and contrasts the work of two doctors in Finland, Elias Lönnrot and Reijo Norio, working over a century and a half apart, to examine the ways in which they have contributed to the formation of national identity and unity. The notion of genetic romanticism is introduced as a term...... to complement the notion of national romanticism that has been used to describe the ways in which nineteenth-century scholars sought to create and deploy common traditions for national-romantic purposes. Unlike national romanticism, however, strategies of genetic romanticism rely on the study of genetic...... inheritance as a way to unify populations within politically and geographically bounded areas. Thus, new genetics have contributed to the development of genetic romanticisms, whereby populations (human, plant, and animal) can be delineated and mobilized through scientific and medical practices to represent...

  10. Long distance signaling using axionlike particles

    Science.gov (United States)

    Stancil, Daniel D.

    2007-12-01

    The possible existence of axionlike particles could lead to a new type of long-distance communication. In this work, basic antenna concepts are defined and a Friis-like equation is derived to facilitate long-distance link calculations. An example calculation is presented showing that communication over distances of 1000 km or more may be possible for ma5×10-8GeV-1.

  11. Inverse Distance Weighted Interpolation Involving Position Shading

    OpenAIRE

    Li, Zhengquan; WU Yaoxiang

    2015-01-01

    Considering the shortcomings of inverse distance weighted (IDW) interpolation in practical applications, this study improved the IDW algorithm and put forward a new spatial interpolation method that named as adjusted inverse distance weighted (AIDW). In interpolating process, the AIDW is capable of taking into account the comprehensive influence of distance and position of sample point to interpolation point, by adding a coefficient (K) into the normal IDW formula. The coefficient (K) is used...

  12. Sublinear distance labeling for sparse graphs

    DEFF Research Database (Denmark)

    Alstrup, Stephen; Dahlgaard, Søren; Knudsen, Mathias Bæk Tejs;

    2015-01-01

    between pairs of nodes that are at distance at least $D$ from each other. In this paper we consider distance labeling schemes for the classical case of unweighted and undirected graphs. We present the first distance labeling scheme of size $o(n)$ for sparse graphs (and hence bounded degree graphs......). This addresses an open problem by Gavoille et. al. [J. Algo. 2004], hereby separating the complexity from general graphs which require $\\Omega(n)$ size Moon [Proc. of Glasgow Math. Association 1965]. As an intermediate result we give a $O(\\frac{n}{D}\\log^2 D)$ $D$-preserving distance labeling scheme, improving...

  13. A Cognitively Grounded Measure of Pronunciation Distance

    Science.gov (United States)

    Wieling, Martijn; Nerbonne, John; Bloem, Jelke; Gooskens, Charlotte; Heeringa, Wilbert; Baayen, R. Harald

    2014-01-01

    In this study we develop pronunciation distances based on naive discriminative learning (NDL). Measures of pronunciation distance are used in several subfields of linguistics, including psycholinguistics, dialectology and typology. In contrast to the commonly used Levenshtein algorithm, NDL is grounded in cognitive theory of competitive reinforcement learning and is able to generate asymmetrical pronunciation distances. In a first study, we validated the NDL-based pronunciation distances by comparing them to a large set of native-likeness ratings given by native American English speakers when presented with accented English speech. In a second study, the NDL-based pronunciation distances were validated on the basis of perceptual dialect distances of Norwegian speakers. Results indicated that the NDL-based pronunciation distances matched perceptual distances reasonably well with correlations ranging between 0.7 and 0.8. While the correlations were comparable to those obtained using the Levenshtein distance, the NDL-based approach is more flexible as it is also able to incorporate acoustic information other than sound segments. PMID:24416119

  14. A cognitively grounded measure of pronunciation distance.

    Science.gov (United States)

    Wieling, Martijn; Nerbonne, John; Bloem, Jelke; Gooskens, Charlotte; Heeringa, Wilbert; Baayen, R Harald

    2014-01-01

    In this study we develop pronunciation distances based on naive discriminative learning (NDL). Measures of pronunciation distance are used in several subfields of linguistics, including psycholinguistics, dialectology and typology. In contrast to the commonly used Levenshtein algorithm, NDL is grounded in cognitive theory of competitive reinforcement learning and is able to generate asymmetrical pronunciation distances. In a first study, we validated the NDL-based pronunciation distances by comparing them to a large set of native-likeness ratings given by native American English speakers when presented with accented English speech. In a second study, the NDL-based pronunciation distances were validated on the basis of perceptual dialect distances of Norwegian speakers. Results indicated that the NDL-based pronunciation distances matched perceptual distances reasonably well with correlations ranging between 0.7 and 0.8. While the correlations were comparable to those obtained using the Levenshtein distance, the NDL-based approach is more flexible as it is also able to incorporate acoustic information other than sound segments.

  15. Maximum likelihood estimates of pairwise rearrangement distances.

    Science.gov (United States)

    Serdoz, Stuart; Egri-Nagy, Attila; Sumner, Jeremy; Holland, Barbara R; Jarvis, Peter D; Tanaka, Mark M; Francis, Andrew R

    2017-06-21

    Accurate estimation of evolutionary distances between taxa is important for many phylogenetic reconstruction methods. Distances can be estimated using a range of different evolutionary models, from single nucleotide polymorphisms to large-scale genome rearrangements. Corresponding corrections for genome rearrangement distances fall into 3 categories: Empirical computational studies, Bayesian/MCMC approaches, and combinatorial approaches. Here, we introduce a maximum likelihood estimator for the inversion distance between a pair of genomes, using a group-theoretic approach to modelling inversions introduced recently. This MLE functions as a corrected distance: in particular, we show that because of the way sequences of inversions interact with each other, it is quite possible for minimal distance and MLE distance to differently order the distances of two genomes from a third. The second aspect tackles the problem of accounting for the symmetries of circular arrangements. While, generally, a frame of reference is locked, and all computation made accordingly, this work incorporates the action of the dihedral group so that distance estimates are free from any a priori frame of reference. The philosophy of accounting for symmetries can be applied to any existing correction method, for which examples are offered. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. A cognitively grounded measure of pronunciation distance.

    Directory of Open Access Journals (Sweden)

    Martijn Wieling

    Full Text Available In this study we develop pronunciation distances based on naive discriminative learning (NDL. Measures of pronunciation distance are used in several subfields of linguistics, including psycholinguistics, dialectology and typology. In contrast to the commonly used Levenshtein algorithm, NDL is grounded in cognitive theory of competitive reinforcement learning and is able to generate asymmetrical pronunciation distances. In a first study, we validated the NDL-based pronunciation distances by comparing them to a large set of native-likeness ratings given by native American English speakers when presented with accented English speech. In a second study, the NDL-based pronunciation distances were validated on the basis of perceptual dialect distances of Norwegian speakers. Results indicated that the NDL-based pronunciation distances matched perceptual distances reasonably well with correlations ranging between 0.7 and 0.8. While the correlations were comparable to those obtained using the Levenshtein distance, the NDL-based approach is more flexible as it is also able to incorporate acoustic information other than sound segments.

  17. National Wind Distance Learning Collaborative

    Energy Technology Data Exchange (ETDEWEB)

    Dr. James B. Beddow

    2013-03-29

    Executive Summary The energy development assumptions identified in the Department of Energy's position paper, 20% Wind Energy by 2030, projected an exploding demand for wind energy-related workforce development. These primary assumptions drove a secondary set of assumptions that early stage wind industry workforce development and training paradigms would need to undergo significant change if the workforce needs were to be met. The current training practice and culture within the wind industry is driven by a relatively small number of experts with deep field experience and knowledge. The current training methodology is dominated by face-to-face, classroom based, instructor present training. Given these assumptions and learning paradigms, the purpose of the National Wind Distance Learning Collaborative was to determine the feasibility of developing online learning strategies and products focused on training wind technicians. The initial project scope centered on (1) identifying resources that would be needed for development of subject matter and course design/delivery strategies for industry-based (non-academic) training, and (2) development of an appropriate Learning Management System (LMS). As the project unfolded, the initial scope was expanded to include development of learning products and the addition of an academic-based training partner. The core partners included two training entities, industry-based Airstreams Renewables and academic-based Lake Area Technical Institute. A third partner, Vision Video Interactive, Inc. provided technology-based learning platforms (hardware and software). The revised scope yielded an expanded set of results beyond the initial expectation. Eight learning modules were developed for the industry-based Electrical Safety course. These modules were subsequently redesigned and repurposed for test application in an academic setting. Software and hardware developments during the project's timeframe enabled redesign providing

  18. Research on Distance Education Development in China

    Science.gov (United States)

    Xin, Ding; Jian, Niu; Yanhui, Han

    2010-01-01

    Distance education is among the significant fields for the application of educational technology. Distance education in China has gone through three phases, namely: correspondence-based education, radio and TV-based education and online education. This paper was based on educational technology application, and the historical, dialectic and…

  19. Binding Principle for Long-Distance Anaphors.

    Science.gov (United States)

    Choi, Dong-Ik

    1997-01-01

    An analysis of long-distance anaphora, a binding phenomenon in which reflexives find their antecedents outside their local domain, is presented, using data from English, Chinese, Japanese, Korean, Russian, Icelandic, and Italian. It is found that no approach deals with long-distance anaphors exclusively and elegantly. The binding domain…

  20. Isolation by language and distance in Belgium.

    Science.gov (United States)

    Barrai, I; Rodriguez-Larralde, A; Manni, F; Ruggiero, V; Tartari, D; Scapoli, C

    2004-01-01

    The isonymy structure of trilingual Belgium was studied using the surname distributions for 1,118,004 private telephone users. The users were distributed in 77 Flemish, 76 French, and 3 German speaking towns, selected on a geographic basis to form an approximately regular grid over Belgium. Lasker's distance was found to be considerably higher between languages than within languages. For the whole of Belgium, irrespective of language, it was highly correlated with linear geographic distance, with r = 0.721+/-0.014, which is the highest correlation observed in European countries to date. Within Belgium and within languages, the correlation was highest among the Flemish (r = 0.878 +/- 0.007), and lowest among the French (r = 0.631+/-0.020). Isolation by distance in Belgium is the highest we have found in Europe, and as high as in Switzerland where the different languages are separated by geographical barriers. This is not the case in Belgium, so that the considerable isolating power of languages emerges clearly from the present analysis. From the comparison of Lasker's distance between (9.48) and within (8.16) languages, and from its regression over geographic distance (b = 0.01206), it was possible to establish a quantitative relationship between the isolating power of languages and that of geographic distance as (9.48-8.16)/0.01206 = 109 kilometres. This transformation of language distance into an equivalent geographic distance, given here for Belgium, can be applied to any similar geo-linguistic situation.

  1. Language Distance Learning for the Digital Generation

    Science.gov (United States)

    Duran-Cerda, Dolores

    2010-01-01

    The purpose of this article was to shed light on the potential of distance learning to overcome challenges in distance, space, time, and human and economic resources that limit access to language learning opportunities in cultural, literary, historical, geographical, and cross-cultural frames. Language and literature educators collectively have…

  2. Designing legible fonts for distance reading

    DEFF Research Database (Denmark)

    Beier, Sofie

    2016-01-01

    This chapter reviews existing knowledge on distance legibility of fonts, and finds that for optimal distance reading, letters and numbers benefit from relative wide shapes, open inner counters and a large x-height; fonts should further be widely spaced, and the weight should not be too heavy or t...

  3. Sensor Network Localization with Imprecise Distances

    NARCIS (Netherlands)

    Cao, M.; Morse, A.S.; Anderson, B.D.O.

    2006-01-01

    An approach to formulate geometric relations among distances between nodes as equality constraints is introduced in this paper to study the localization problem with imprecise distance information in sensor networks. These constraints can be further used to formulate optimization problems for distan

  4. A Survey on Distance Vector Routing Protocols

    CERN Document Server

    Tang, Linpeng

    2011-01-01

    In this paper we give a brief introduction to five different distance vector routing protocols (RIP, AODV, EIGRP, RIP-MTI and Babel) and give some of our thoughts on how to solve the count to infinity problem. Our focus is how distance vector routing protocols, based on limited information, can prevent routing loops and the count to infinity problem.

  5. Who Graduates from Irish Distance University Education?

    Science.gov (United States)

    Delaney, Lorraine

    2015-01-01

    This paper outlines results from an online survey of recent distance graduates. The study, based in Dublin City University (DCU) addresses a gap in the research on this cohort of graduates. Findings indicate that distance graduates are primarily from lower socio economic backgrounds, a group largely under-represented in full-time university…

  6. Distance Education for People with Visual Impairments

    Science.gov (United States)

    Liakou, Maria; Manousou, Evaggelia

    2015-01-01

    This paper studies the standards of higher Distance Education, focusing on the Hellenic Open University, for people who have visual impairments, so that it becomes fully accessible and thus helps reduce social exclusion. Specifically, it aims to study the operational context of Distance Education, the possibilities that modern technology provides…

  7. Audiences and Providers of Distance Education

    Science.gov (United States)

    Nazarinia Roy, R. Roudi; Schumm, Walter R.

    2011-01-01

    As noted by Moore (2007, xxiii), the fifth section of the second edition of the "Handbook of Distance Education" focused on "some of the main consumers and suppliers of distance education programs," including elementary and secondary education, community colleges, universities, the corporate sector, continuing professional…

  8. Investigating Distance Education Students' Study Skills

    Science.gov (United States)

    Poyraz, Cengiz

    2013-01-01

    Distance education, which is a planned way of teaching in which students and instructors are brought face to face in a classroom environment in several different ways by means of technology, has started to become widespread in many fields today. In distance education, students and instructors reside in different locations. Students can learn at…

  9. Applying Leadership Theories to Distance Education Leadership

    Science.gov (United States)

    Nworie, John

    2012-01-01

    The instructional delivery mode in distance education has been transitioning from the context of a physical classroom environment to a virtual learning environment or maintaining a hybrid of the two. However, most distance education programs in dual mode institutions are situated in traditional face-to-face instructional settings. Distance…

  10. Distance Education Report, 2011-2012

    Science.gov (United States)

    California Community Colleges, Chancellor's Office, 2013

    2013-01-01

    This is a report on distance education in the California Community College. This is the seventh report to the California Community Colleges Board of Governors (BOG) per BOG Standing Order 409 (b) "that evaluates the effectiveness of distance education and education technology system wide and provides analysis of data demographically (by age,…

  11. Three Generations of Distance Education Pedagogy

    Science.gov (United States)

    Anderson, Terry; Dron, Jon

    2011-01-01

    This paper defines and examines three generations of distance education pedagogy. Unlike earlier classifications of distance education based on the technology used, this analysis focuses on the pedagogy that defines the learning experiences encapsulated in the learning design. The three generations of cognitive-behaviourist, social constructivist,…

  12. Institutional and specialized Distance learning program accreditation

    Directory of Open Access Journals (Sweden)

    Mehzabul Hoque Nahid

    2015-09-01

    Full Text Available Teaching and learning are no longer confined to the classroom or the school day. There are many technologies that can offer a great deal of flexibility in when, where, and how education is distributed. The Teacher's Guide to Distance Learning is intended for K-12 educators who are interested in implementing distance learning technologies. It provides an overview of the advantages and characteristics of the various technologies now being used to reach remote learners. Distance learning provides "access to learning when the source of information and the learners are separated by time and distance, or both." Distance education courses that require a physical on-site presence for any reason (excluding taking examinations may be referred to as hybrid or blended courses of study. Massive open online courses (MOOCs, aimed at large-scale interactive participation and open access via the web or other network technologies, are recent developments in distance education. A number of other terms are used roughly synonymously with distance education. However distance is the oldest and mostly commonly used term globally. It is also the broadest term and has the largest collection of related research articles. The main objective of this paper is develop an understanding of the characteristics and needs of distant students with little first-hand experience and limited, if any, face-to-face contact.

  13. When Do Distance Effects Become Empirically Observable?

    DEFF Research Database (Denmark)

    Beugelsdijk, Sjoerd; Nell, Phillip C.; Ambos, Björn

    2017-01-01

    , on average, distance is unrelated to value added by headquarters but that this effect is contingent upon the extent to which the subsidiary is locally embedded. Only after a certain threshold level of subsidiary embeddedness, distance is negatively related to headquarters value added. This effect is more...

  14. Measuring Distances to Remote Galaxies and Quasars.

    Science.gov (United States)

    McCarthy, Patrick J.

    1988-01-01

    Describes the use of spectroscopy and the redshift to measure how far an object is by measuring how fast it is receding from earth. Lists the most distant quasars yet found. Tables include "Redshift vs. Distance" and "Distances to Celestial Objects for Various Cosmologies." (CW)

  15. NASA Langley/CNU Distance Learning Programs.

    Science.gov (United States)

    Caton, Randall; Pinelli, Thomas E.

    NASA Langley Research Center and Christopher Newport University (CNU) provide, free to the public, distance learning programs that focus on math, science, and/or technology over a spectrum of education levels from K-adult. The effort started in 1997, and currently there are a suite of five distance-learning programs. This paper presents the major…

  16. Measuring Norwegian dialect distances using acoustic features

    NARCIS (Netherlands)

    Heeringa, Wilbert; Johnson, Keith; Gooskens, Charlotte

    2009-01-01

    Levenshtein distance has become a popular tool for measuring linguistic dialect distances, and has been applied to Irish Gaelic, Dutch, German and other dialect groups. The method, in the current state of the art, depends upon phonetic transcriptions, even when acoustic differences are used the numb

  17. Spectral distance on the Moyal plane

    Energy Technology Data Exchange (ETDEWEB)

    Martinetti, Pierre [Universitaet Goettingen (Germany). Courant Centre

    2010-07-01

    We compute the spectral distance, defined in Connes' noncommutative geometry, in the Moyal plane. We find that the distance between the eigenstates m,m+1 of the quantum harmonic oscillator is proportional to m{sup -1/2}. We also show how to truncate the Moyal spectral triple in order to obtain quantum metric spaces in the sense of Rieffel.

  18. Applying Leadership Theories to Distance Education Leadership

    Science.gov (United States)

    Nworie, John

    2012-01-01

    The instructional delivery mode in distance education has been transitioning from the context of a physical classroom environment to a virtual learning environment or maintaining a hybrid of the two. However, most distance education programs in dual mode institutions are situated in traditional face-to-face instructional settings. Distance…

  19. Cultural Distance Asymmetry in Expatriate Adjustment

    DEFF Research Database (Denmark)

    Selmer, Jan; Chiu, Randy K.; Shenkar, Oded

    2007-01-01

    Purpose - The current literature implicitly assumes a symmetric impact of cultural distance (CD) on expatriate adjustment. By using distance as a predictor of adjustment, the literature has rendered the direction of the flow irrelevant: a US expatriate in Germany is presumed to face the same hurd...

  20. Cosmological distance indicators by coalescing binaries

    CERN Document Server

    De Laurentis, Mariafelicia; De Martino, Ivan; Formisano, Michelangelo

    2011-01-01

    Gravitational waves detected from well-localized inspiraling binaries would allow to determine, directly and independently, both binary luminosity and redshift. In this case, such systems could behave as "standard candles" providing an excellent probe of cosmic distances up to z < 0.1 and thus complementing other indicators of cosmological distance ladder.

  1. Distance Education for People with Visual Impairments

    Science.gov (United States)

    Liakou, Maria; Manousou, Evaggelia

    2015-01-01

    This paper studies the standards of higher Distance Education, focusing on the Hellenic Open University, for people who have visual impairments, so that it becomes fully accessible and thus helps reduce social exclusion. Specifically, it aims to study the operational context of Distance Education, the possibilities that modern technology provides…

  2. Introduction : The Metaphor of Historical Distance

    NARCIS (Netherlands)

    Den Hollander, Jaap; Paul, Herman; Peters, Rik

    2011-01-01

    What does "historical distance" mean? Starting with Johan Huizinga, the famous Dutch historian who refused to lecture on contemporary history, this introductory article argues that "historical distance" is a metaphor used in a variety of intellectual contexts. Accordingly, the metaphor has ontologic

  3. Exploring Cloud Computing for Distance Learning

    Science.gov (United States)

    He, Wu; Cernusca, Dan; Abdous, M'hammed

    2011-01-01

    The use of distance courses in learning is growing exponentially. To better support faculty and students for teaching and learning, distance learning programs need to constantly innovate and optimize their IT infrastructures. The new IT paradigm called "cloud computing" has the potential to transform the way that IT resources are utilized and…

  4. Distance Education in India Present and Future.

    Science.gov (United States)

    Datt, Ruddar

    Distance education is offered by 4 universities and 34 institutes/directorates in India. All open universities have been brought under the direction of the Indira Gandhi National Open University with regard to networking and determination of grants. The networking has avoided unnecessary duplication of course preparation costs. Distance education…

  5. Challenges Encountered by a Distance Learning Organisation

    Science.gov (United States)

    Malik, Sangeeta

    2012-01-01

    Distance learning as the name indicates is a learning, learner gets from distant places. In this learning system, learner and educators are separated by space & time. Lots of distance learning organizations are spreading to meet the increased demand of current & future needs of adult education. The rapid spread of these organizations doesn't mean…

  6. Effects of Distance Learning on Learning Effectiveness

    Science.gov (United States)

    Liu, Hong-Cheng; Yen, Jih-Rong

    2014-01-01

    The development of computers in the past two decades has resulted in the changes of education in enterprises and schools. The advance of computer hardware and platforms allow colleges generally applying distance courses to instruction that both Ministry of Education and colleges have paid attention to the development of Distance Learning. To…

  7. Key Instructional Design Elements for Distance Education.

    Science.gov (United States)

    Zheng, Lihua; Smaldino, Sharon

    2003-01-01

    Suggests that distance education instructors need to understand and apply important instructional design elements in order to successfully fulfill their role as instructional designers. Reviews the most recent literature pertaining to designing instruction in distance education. Identifies some key instructional design elements for teaching at a…

  8. Measuring Norwegian dialect distances using acoustic features

    NARCIS (Netherlands)

    Heeringa, Wilbert; Johnson, Keith; Gooskens, Charlotte

    Levenshtein distance has become a popular tool for measuring linguistic dialect distances, and has been applied to Irish Gaelic, Dutch, German and other dialect groups. The method, in the current state of the art, depends upon phonetic transcriptions, even when acoustic differences are used the

  9. Modes of Production: Fordism and Distance Education.

    Science.gov (United States)

    Farnes, Nick

    1993-01-01

    Analyzes the historical development of economic and educational systems and considers the relationship between industrialization and distance education. Modes of production and stages of conventional and distance education development are described, and future possibilities of mass higher and continuing education through the use of computer-based…

  10. Exploring Cloud Computing for Distance Learning

    Science.gov (United States)

    He, Wu; Cernusca, Dan; Abdous, M'hammed

    2011-01-01

    The use of distance courses in learning is growing exponentially. To better support faculty and students for teaching and learning, distance learning programs need to constantly innovate and optimize their IT infrastructures. The new IT paradigm called "cloud computing" has the potential to transform the way that IT resources are utilized and…

  11. A Roman Dodecahedron for measuring distance

    CERN Document Server

    Sparavigna, Amelia Carolina

    2012-01-01

    Here I am discussing a possible use of a Roman Dodecahedron, a bronze artifact of gallo-roman origin, for measuring distance. A dodecahedron, found at Jublains, the ancient Nouiodunum, dating from the 2nd or 3rd century AD, is used to create a model. Looking through the model, it is possible to test it for measurements of distance based on similar triangles.

  12. New Strategy of the Distance Education

    Science.gov (United States)

    Bunyatova, Fatma Khanim; Salamov, Gulbala

    2014-01-01

    This article is dedicated to new strategy of distance education. The article deals with the possibilities of ICT (Information and Communication Technologies) in teaching specially distance education. In the article, ICT technological tools and their methods of application in educational process are looked over; discrepancy of intellectual…

  13. DISTANCES IN THE SPACES OF STATISTICAL DATA

    Directory of Open Access Journals (Sweden)

    Orlov A. I.

    2014-09-01

    Full Text Available The core of applied statistics is statistics in spaces of arbitrary nature, based on the use of distances and optimization problems. This article discusses the various distances in spaces of statistical data, in particular, their conclusions on the basis of appropriate systems of axioms. The conditions and proofs of theorems first published in scientific periodicals

  14. Genetic Breakthrough

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A new calf breeding technique shows promise for treating malignant tumors Chinese scientists have successfully bred a genetically altered cow capable of producing cancer-curing proteins for human beings.

  15. Three Generations of Distance Education Pedagogy

    Directory of Open Access Journals (Sweden)

    Terry Anderson

    2011-03-01

    Full Text Available This paper defines and examines three generations of distance education pedagogy. Unlike earlier classifications of distance education based on the technology used, this analysis focuses on the pedagogy that defines the learning experiences encapsulated in the learning design. The three generations of cognitive-behaviourist, social constructivist, and connectivist pedagogy are examined, using the familiar community of inquiry model (Garrison, Anderson, & Archer, 2000 with its focus on social, cognitive, and teaching presences. Although this typology of pedagogies could also be usefully applied to campus-based education, the need for and practice of openness and explicitness in distance education content and process makes the work especially relevant to distance education designers, teachers, and developers. The article concludes that high-quality distance education exploits all three generations as determined by the learning content, context, and learning expectations.

  16. Automatic analysis of distance bounding protocols

    CERN Document Server

    Malladi, Sreekanth; Kothapalli, Kishore

    2010-01-01

    Distance bounding protocols are used by nodes in wireless networks to calculate upper bounds on their distances to other nodes. However, dishonest nodes in the network can turn the calculations both illegitimate and inaccurate when they participate in protocol executions. It is important to analyze protocols for the possibility of such violations. Past efforts to analyze distance bounding protocols have only been manual. However, automated approaches are important since they are quite likely to find flaws that manual approaches cannot, as witnessed in literature for analysis pertaining to key establishment protocols. In this paper, we use the constraint solver tool to automatically analyze distance bounding protocols. We first formulate a new trace property called Secure Distance Bounding (SDB) that protocol executions must satisfy. We then classify the scenarios in which these protocols can operate considering the (dis)honesty of nodes and location of the attacker in the network. Finally, we extend the const...

  17. Simple expressions for the long walk distance

    CERN Document Server

    Chebotarev, Pavel; Balaji, R

    2011-01-01

    The walk distances in graphs are defined as the result of appropriate transformations of the $\\sum_{k=0}^\\infty(tA)^k$ proximity measures, where $A$ is the weighted adjacency matrix of a connected weighted graph and $t$ is a sufficiently small positive parameter. The walk distances are graph-geodetic, moreover, they converge to the shortest path distance and to the so-called long walk distance as the parameter $t$ approaches its limiting values. In this paper, simple expressions for the long walk distance are obtained. They involve the generalized inverse, minors, and inverses of submatrices of the symmetric irreducible singular M-matrix ${\\cal L}=\\rho I-A,$ where $\\rho$ is the Perron root of $A.$

  18. Mitochondrial genetics

    OpenAIRE

    Chinnery, Patrick Francis; Hudson, Gavin

    2013-01-01

    Introduction In the last 10 years the field of mitochondrial genetics has widened, shifting the focus from rare sporadic, metabolic disease to the effects of mitochondrial DNA (mtDNA) variation in a growing spectrum of human disease. The aim of this review is to guide the reader through some key concepts regarding mitochondria before introducing both classic and emerging mitochondrial disorders. Sources of data In this article, a review of the current mitochondrial genetics literature was con...

  19. Distance Learning. Volume II: Course Analysis Manual for Conversion to Distance Learning.

    Science.gov (United States)

    1998-09-01

    The primary focus of this project is the determination of the feasibility and cost effectiveness of applying Distance Learning strategies to 22...selected PPSCP courses and development of a Distance Learning Analysis Procedures Manual.

  20. Euglossine bees mediate only limited long-distance gene flow in a tropical vine.

    Science.gov (United States)

    Opedal, Øystein H; Falahati-Anbaran, Mohsen; Albertsen, Elena; Armbruster, W Scott; Pérez-Barrales, Rocío; Stenøien, Hans K; Pélabon, Christophe

    2017-03-01

    Euglossine bees (Apidae: Euglossini) have long been hypothesized to act as long-distance pollinators of many low-density tropical plants. We tested this hypothesis by the analysis of gene flow and genetic structure within and among populations of the euglossine bee-pollinated vine Dalechampia scandens. Using microsatellite markers, we assessed historical gene flow by the quantification of regional-scale genetic structure and isolation by distance among 18 populations, and contemporary gene flow by the estimation of recent migration rates among populations. To assess bee-mediated pollen dispersal on a smaller scale, we conducted paternity analyses within a focal population, and quantified within-population spatial genetic structure in four populations. Gene flow was limited to certain nearby populations within continuous forest blocks, whereas drift appeared to dominate on larger scales. Limited long-distance gene flow was supported by within-population patterns; gene flow was biased towards nearby plants, and significant small-scale spatial genetic structure was detected within populations. These findings suggest that, although female euglossine bees might be effective at moving pollen within populations, and perhaps within forest blocks, their contribution to gene flow on the regional scale seems too limited to counteract genetic drift in patchily distributed tropical plants. Among-population gene flow might have been reduced following habitat fragmentation.

  1. The ideal subject distance for passport pictures.

    Science.gov (United States)

    Verhoff, Marcel A; Witzel, Carsten; Kreutz, Kerstin; Ramsthaler, Frank

    2008-07-04

    In an age of global combat against terrorism, the recognition and identification of people on document images is of increasing significance. Experiments and calculations have shown that the camera-to-subject distance - not the focal length of the lens - can have a significant effect on facial proportions. Modern passport pictures should be able to function as a reference image for automatic and manual picture comparisons. This requires a defined subject distance. It is completely unclear which subject distance, in the taking of passport photographs, is ideal for the recognition of the actual person. We show here that the camera-to-subject distance that is perceived as ideal is dependent on the face being photographed, even if the distance of 2m was most frequently preferred. So far the problem of the ideal camera-to-subject distance for faces has only been approached through technical calculations. We have, for the first time, answered this question experimentally with a double-blind experiment. Even if there is apparently no ideal camera-to-subject distance valid for every face, 2m can be proposed as ideal for the taking of passport pictures. The first step would actually be the determination of a camera-to-subject distance for the taking of passport pictures within the standards. From an anthropological point of view it would be interesting to find out which facial features allow the preference of a shorter camera-to-subject distance and which allow the preference of a longer camera-to-subject distance.

  2. On Properties of the Generalized Wasserstein Distance

    Science.gov (United States)

    Piccoli, Benedetto; Rossi, Francesco

    2016-12-01

    The Wasserstein distances W p ( p {≥q} 1), defined in terms of a solution to the Monge-Kantorovich problem, are known to be a useful tool to investigate transport equations. In particular, the Benamou-Brenier formula characterizes the square of the Wasserstein distance W 2 as the infimum of the kinetic energy, or action functional, of all vector fields transporting one measure to the other. Another important property of the Wasserstein distances is the Kantorovich-Rubinstein duality, stating the equality between the distance W 1( μ, ν) of two probability measures μ, ν and the supremum of the integrals in d( μ - ν) of Lipschitz continuous functions with Lipschitz constant bounded by one. An intrinsic limitation of Wasserstein distances is the fact that they are defined only between measures having the same mass. To overcome such a limitation, we recently introduced the generalized Wasserstein distances {W_p^{a,b}}, defined in terms of both the classical Wasserstein distance W p and the total variation (or L 1) distance, see (Piccoli and Rossi in Archive for Rational Mechanics and Analysis 211(1):335-358, 2014). Here p plays the same role as for the classic Wasserstein distance, while a and b are weights for the transport and the total variation term. In this paper we prove two important properties of the generalized Wasserstein distances: (1) a generalized Benamou-Brenier formula providing the equality between {W_2^{a,b}} and the supremum of an action functional, which includes a transport term (kinetic energy) and a source term; (2) a duality à la Kantorovich-Rubinstein establishing the equality between {W_1^{1,1}} and the flat metric.

  3. Distance software: design and analysis of distance sampling surveys for estimating population size.

    Science.gov (United States)

    Thomas, Len; Buckland, Stephen T; Rexstad, Eric A; Laake, Jeff L; Strindberg, Samantha; Hedley, Sharon L; Bishop, Jon Rb; Marques, Tiago A; Burnham, Kenneth P

    2010-02-01

    1.Distance sampling is a widely used technique for estimating the size or density of biological populations. Many distance sampling designs and most analyses use the software Distance.2.We briefly review distance sampling and its assumptions, outline the history, structure and capabilities of Distance, and provide hints on its use.3.Good survey design is a crucial prerequisite for obtaining reliable results. Distance has a survey design engine, with a built-in geographic information system, that allows properties of different proposed designs to be examined via simulation, and survey plans to be generated.4.A first step in analysis of distance sampling data is modelling the probability of detection. Distance contains three increasingly sophisticated analysis engines for this: conventional distance sampling, which models detection probability as a function of distance from the transect and assumes all objects at zero distance are detected; multiple-covariate distance sampling, which allows covariates in addition to distance; and mark-recapture distance sampling, which relaxes the assumption of certain detection at zero distance.5.All three engines allow estimation of density or abundance, stratified if required, with associated measures of precision calculated either analytically or via the bootstrap.6.Advanced analysis topics covered include the use of multipliers to allow analysis of indirect surveys (such as dung or nest surveys), the density surface modelling analysis engine for spatial and habitat modelling, and information about accessing the analysis engines directly from other software.7.Synthesis and applications. Distance sampling is a key method for producing abundance and density estimates in challenging field conditions. The theory underlying the methods continues to expand to cope with realistic estimation situations. In step with theoretical developments, state-of-the-art software that implements these methods is described that makes the methods

  4. Rethinking Distance Learning Activities: A Comparison of Transactional Distance Theory and Activity Theory

    Science.gov (United States)

    Kang, Haijun; Gyorke, Allan S.

    2008-01-01

    Despite its invaluable guidance to distance education development, transactional distance (TD) theory is not seamlessly synchronised with current field practice and lacks a social component. After it has provided over 30 years of guidance, there is now a need to re-appraise TD's propositions about distance learning activities. The social-cultural…

  5. The Cost of Distance Education. IEC Broadsheets on Distance Learning No. 17.

    Science.gov (United States)

    Perraton, Hilary

    One of a series offering practical advice and information on distance teaching, this broadsheet first looks at the reasons for trying to measure distance teaching costs and the methodological and economic difficulties involved in such measurements. Broadcasting and print costs in distance teaching are discussed, and evidence about the costs of…

  6. Secondary Education at a Distance. IEC Broadsheets on Distance Learning No. 12.

    Science.gov (United States)

    Perraton, Hilary

    One of a series offering practical advice and information on distance teaching, this broadsheet focuses on the ways in which distance teaching can support, expand, and change secondary education. Traditional criticisms of secondary schools are examined, including their irrelevancy, inefficiency, and inequity. Issues of distance education…

  7. Horizontal Distance Travelled by a Mobile Experiencing a Quadratic Drag Force: Normalized Distance and Parametrization

    Science.gov (United States)

    Vial, Alexandre

    2007-01-01

    We investigate the problem of the horizontal distance travelled by a mobile experiencing a quadratic drag force. We show that by introducing a normalized distance, the problem can be greatly simplified. In order to parametrize this distance, we use the Pearson VII function, and we find that the optimal launch angle as a function of the initial…

  8. Secondary Education at a Distance. IEC Broadsheets on Distance Learning No. 12.

    Science.gov (United States)

    Perraton, Hilary

    One of a series offering practical advice and information on distance teaching, this broadsheet focuses on the ways in which distance teaching can support, expand, and change secondary education. Traditional criticisms of secondary schools are examined, including their irrelevancy, inefficiency, and inequity. Issues of distance education…

  9. The Cost of Distance Education. IEC Broadsheets on Distance Learning No. 17.

    Science.gov (United States)

    Perraton, Hilary

    One of a series offering practical advice and information on distance teaching, this broadsheet first looks at the reasons for trying to measure distance teaching costs and the methodological and economic difficulties involved in such measurements. Broadcasting and print costs in distance teaching are discussed, and evidence about the costs of…

  10. Has Distance Learning Become More Flexible? Reflections of a Distance Learning Student

    Science.gov (United States)

    Thomas, Theda

    2012-01-01

    This paper provides insight into the way in which distance learning had changed over the past 30 years from the perspective of the author as a distance learning student. The question is then asked as to whether current practice is reducing flexibility for distance learning students? The paper starts with a discussion of flexible learning and the…

  11. Labour Market Theories and Distance Education I: Industrialization and Distance Education.

    Science.gov (United States)

    Rumble, Greville

    1995-01-01

    Addresses industrialization and distance education and how they relate to the modernist and postmodernist models of work, Fordism, neo-Fordism and post-Fordism. Concludes that not all distance education is industrialized; traditional education is not always a craft; and Fordism does not adequately explain the development of distance education.…

  12. The small genetic world of Seriatopora hystrix

    Directory of Open Access Journals (Sweden)

    Stuart Kininmonth

    2012-03-01

    Full Text Available The exchange of genetic information among coral reefs, through the transport of larvae, is critical to the function of Australia's Great Barrier Reef because it influences recruitment rates and resilience to disturbance. For many species the genetic composition is not homogeneous and is determined, in part, by the character of the complex dispersal pathways that connect the populations situated on each coral reef. One method of measuring these genetic connections is to examine the microsatellite composition of individual corals and then statistically compare populations across the region. We use these connection strengths, derived from a population similarity measure, to create complex networks to describe and analyse the genetic exchange of the brooding coral, Seriatopora hystrix. The network, based on determining the putative parental origin of individual coral colonies, involved sampling 2163 colonies from 47 collection sites and examining 10 microsatellites. A dispersal network was created from the genetic distance DLR values that measure the genetic similarity of each population (defined by the local sampling effort to every other sampled population based on the microsatellite composition. Graph theory methods show that this network exhibited infrequent long distance links and population clustering which is commonly referred to as small world topology. Comparison with a hydrodynamic based network indicates that the genetic population network topology is similar. This approach shows the genetic structure of the S. hystrix coral follows a small world pattern which supports the results derived from previous hydrodynamic modelling.

  13. Approximate Graph Edit Distance in Quadratic Time.

    Science.gov (United States)

    Riesen, Kaspar; Ferrer, Miquel; Bunke, Horst

    2015-09-14

    Graph edit distance is one of the most flexible and general graph matching models available. The major drawback of graph edit distance, however, is its computational complexity that restricts its applicability to graphs of rather small size. Recently the authors of the present paper introduced a general approximation framework for the graph edit distance problem. The basic idea of this specific algorithm is to first compute an optimal assignment of independent local graph structures (including substitutions, deletions, and insertions of nodes and edges). This optimal assignment is complete and consistent with respect to the involved nodes of both graphs and can thus be used to instantly derive an admissible (yet suboptimal) solution for the original graph edit distance problem in O(n3) time. For large scale graphs or graph sets, however, the cubic time complexity may still be too high. Therefore, we propose to use suboptimal algorithms with quadratic rather than cubic time for solving the basic assignment problem. In particular, the present paper introduces five different greedy assignment algorithms in the context of graph edit distance approximation. In an experimental evaluation we show that these methods have great potential for further speeding up the computation of graph edit distance while the approximated distances remain sufficiently accurate for graph based pattern classification.

  14. GLOBALIZATION, DISTANCE EDUCATION AND HEGEMONIC FUTURES

    Directory of Open Access Journals (Sweden)

    Glenn RUSSELL

    2007-10-01

    Full Text Available ABSTRACT Consideration of the place of theory in distance education suggests that existing definitions do not adequately account for economic, cultural and historical factors. The application of the notion of hegemonic valency to distance education highlights the ways in which tools, technological systems and online environments operate in predictable ways. Historically, the imperatives of market forces and social justice have displayed a tension that is continued in contemporary contexts including virtual learning environments. A characteristic of this tension can be seen in the forces and interactions associated with globalisation and technology. These forces, in association with others, have contributed to a null curriculum in which some alternatives open to distance education practitioners remain invisible. It is likely that this situation is further compounded by the difficulty of ascertaining what distance education practices are actually operating world-wide at any identifiable time. Available options for distance educators can be understood in terms of instrumental and interpersonal axes that can potentially indicate the relative consideration that can be given to these factors. This approach is suggested as one way to understand available options at a time when there has been an apparent increase in instrumental approaches to distance education at the expense of interpersonal approaches and issues of social justice. While this problem is of concern, it is more appropriate to reflect on the unintended consequences of distance education for society and identify them than it is to uncritically oppose globalisation and its adherents.

  15. Distance-based features in pattern classification

    Directory of Open Access Journals (Sweden)

    Lin Wei-Yang

    2011-01-01

    Full Text Available Abstract In data mining and pattern classification, feature extraction and representation methods are a very important step since the extracted features have a direct and significant impact on the classification accuracy. In literature, numbers of novel feature extraction and representation methods have been proposed. However, many of them only focus on specific domain problems. In this article, we introduce a novel distance-based feature extraction method for various pattern classification problems. Specifically, two distances are extracted, which are based on (1 the distance between the data and its intra-cluster center and (2 the distance between the data and its extra-cluster centers. Experiments based on ten datasets containing different numbers of classes, samples, and dimensions are examined. The experimental results using naïve Bayes, k-NN, and SVM classifiers show that concatenating the original features provided by the datasets to the distance-based features can improve classification accuracy except image-related datasets. In particular, the distance-based features are suitable for the datasets which have smaller numbers of classes, numbers of samples, and the lower dimensionality of features. Moreover, two datasets, which have similar characteristics, are further used to validate this finding. The result is consistent with the first experiment result that adding the distance-based features can improve the classification performance.

  16. Producing Knowledge to Reduce Rhetorical Distance

    DEFF Research Database (Denmark)

    Kampf, Constance

    Producing Knowledge to Reduce Rhetorical Distance: Extending Identity and Engaging Mainstream Ideology via the Web Constance Kampf, Department of Research Knowledge Communication, Aarhus School of Business, Denmark McLuhan describes technologies as extensions -the wheel being an extension...... writers a larger public forum into which they can extend their identity. When the identity being extended represents a minority group, the web offers an opportunity for members of that group to engage mainstream ideology and work at reducing the rhetorical distance between their identity and mainstream...... the opportunity for engaging mainstream ideologies in order to reduce the rhetorical distance between minority and majority cultures....

  17. Transforming distance education curricula through distributive leadership

    Directory of Open Access Journals (Sweden)

    Mike Keppell

    2010-12-01

    Full Text Available This paper examines a core leadership strategy for transforming learning and teaching in distance education through flexible and blended learning. It focuses on a project centred on distributive leadership that involves collaboration, shared purpose, responsibility and recognition of leadership irrespective of role or position within an organisation. Distributive leadership was a core principle in facilitating the transformation of learning and teaching through a Teaching Fellowship Scheme that empowered leaders across a regional distance education university. In parallel, a design-based research project analysed the perceptions of the Teaching Fellows in relation to blended learning, time/space, peer learning, innovation and equity issues in relation to distance education.

  18. Robustness of Distance-to-Default

    DEFF Research Database (Denmark)

    Jessen, Cathrine; Lando, David

    2013-01-01

    Distance-to-default is a remarkably robust measure for ranking firms according to their risk of default. The ranking seems to work despite the fact that the Merton model from which the measure is derived produces default probabilities that are far too small when applied to real data. We use....... A notable exception is a model with stochastic volatility of assets. In this case both the ranking of firms and the estimated default probabilities using distance-to-default perform significantly worse. We therefore propose a volatility adjustment of the distance-to-default measure, that significantly...... improves the ranking of firms with stochastic volatility....

  19. Pragmatic Distance and Appropriateness of Utterance Politeness

    Institute of Scientific and Technical Information of China (English)

    吴丽丽

    2014-01-01

    The Politeness Principle proposed by Leech complements Grice ’ Cooperative Principle to a cer-tain extent in explaining the indirectness of language .However , the nature of politeness is its relativity . Determined by various factors such as social and cultural ones , the appropriateness of politeness at utter-ance level is affected by the appropriateness of the pragmatic distance between the participants .Different from the interpersonal relationships , pragmatic distance is calculated and determined in the process of communication varying with the variation of the communicative factors .Pragmatic distance is dynamic and can be maintained and altered by participants by using certain linguistic expressions to achieve the appro -priateness of politeness in communication .

  20. A New Line Symmetry Distance and Its Application to Data Clustering

    Institute of Scientific and Technical Information of China (English)

    Sriparna Saha; Sanghamitra Bandyopadhyay

    2009-01-01

    In this paper, at first a new line-symmetry-based distance is proposed. The properties of the proposed distance are then elaborately described. Kd-tree-based nearest neighbor search is used to reduce the complexity of computing the proposed line-symmetry-based distance. Thereafter an evolutionary clustering technique is developed that uses the new linesymmetry-based distance measure for assigning points to different clusters. Adaptive mutation and crossover probabilities are used to accelerate the proposed clustering technique. The proposed GA with line-symmetry-distance-based (GALSD)clustering technique is able to detect any type of clusters, irrespective of their geometrical shape and overlapping nature,as long as they possess the characteristics of line symmetry. GALSD is compared with the existing well-known K-means clustering algorithm and a newly developed genetic point-symmetry-distance-based clustering technique (GAPS) for three artificial and two real-life data sets. The efficacy of the proposed line-symmetry-based distance is then shown in recognizing human face from a given image.

  1. Genetic GIScience

    DEFF Research Database (Denmark)

    Jacquez, Geoffrey; Sabel, Clive E; Shi, Chen

    2015-01-01

    The exposome, defined as the totality of an individual's exposures over the life course, is a seminal concept in the environmental health sciences. Although inherently geographic, the exposome as yet is unfamiliar to many geographers. This article proposes a place-based synthesis, genetic...... geographic information science (genetic GIScience), that is founded on the exposome, genome+, and behavome. It provides an improved understanding of human health in relation to biology (the genome+), environmental exposures (the exposome), and their social, societal, and behavioral determinants (the behavome......). Genetic GIScience poses three key needs: first, a mathematical foundation for emergent theory; second, process-based models that bridge biological and geographic scales; third, biologically plausible estimates of space?time disease lags. Compartmental models are a possible solution; this article develops...

  2. GENETIC CONSEQUENCES OF SEED DISPERSAL IN THREE SYMPATRIC FOREST HERBS. I. HIERARCHICAL POPULATION-GENETIC STRUCTURE.

    Science.gov (United States)

    Williams, Charles F; Guries, Raymond P

    1994-06-01

    To examine the effects of seed dispersal on spatial genetic structure, we compare three sympatric species of forest herbs in the family Apiaceae whose fruits differ widely in morphological adaptations for animal-attached dispersal. Cryptotaenia canadensis has smooth fruits that are gravity dispersed, whereas Osmorhiza claytonii and Sanicula odorata fruits have appendages that facilitate their attachment to animals. The relative seed-dispersal ability among species, measured as their ability to remain attached to mammal fur, is ranked Sanicula > Osmorhiza > Cryptotaenia. We use a nested hierarchical sampling design to analyze genetic structure at spatial scales ranging from a few meters to hundreds of kilometers. Genetic differentiation among population subdivisions, estimated by average genetic distance and hierarchical F-statistics, has an inverse relationship with dispersal ability such that Cryptotaenia > Osmorhiza > Sanicula. In each species, genetic differentiation increases with distance among population subdivisions. Stochastic variation in gene flow, arising from seed dispersal by attachment to animals, may partly explain the weak relationship between pairwise spatial and genetic distance among populations and heterogeneity in estimates of single locus F-statistics. A hierarchical island model of gene flow is invoked to describe the effects of seed dispersal on population genetic structure. Seed dispersal is the predominant factor affecting variation in gene flow among these ecologically similar, taxonomically related species. © 1994 The Society for the Study of Evolution.

  3. Research in Distance Education: A Status Report

    Directory of Open Access Journals (Sweden)

    Farhad Saba

    2000-06-01

    Full Text Available Since the 1950s and expansion of social science research, distance education has been studied in comparison to face-to-face or classroom instruction. Although researchers continue to conduct comparative studies, their usefulness in revealing more information has diminished over the years; invariably, they have returned a “no significant difference” result between various forms of instruction. In recent years, researchers have moved beyond atheoretical, experimental comparative studies and have introduced new methods, such as discourse analysis, and in-depth interview of learners. These new methods overcome many methodological and theoretical limitations of the physical science view of distance education. These studies have further revealed the complexity of distance education, indicating the many variables involved in the concept. Starting with the core issue of instructional interaction and grounded on the theory of transactional distance, a new strand of research using methods related to systems dynamics, hierarchy and complexity theories, promises a more comprehensive understanding.

  4. Environmental Impact of Long Distance Travel

    DEFF Research Database (Denmark)

    Christensen, Linda

    2016-01-01

    This paper presents an analysis of the CO2 emission resulting from long distance travel by Danes. The emissions are analysed as the Danes’ footprint the whole way from Denmark to the final destination. International travel represents 31% of the Danes’ CO2 emission from passenger travel and the cl......This paper presents an analysis of the CO2 emission resulting from long distance travel by Danes. The emissions are analysed as the Danes’ footprint the whole way from Denmark to the final destination. International travel represents 31% of the Danes’ CO2 emission from passenger travel...... and the climate burden from long overseas distances is especially high even though only few travel overseas. The travel activity is furthermore increasing much more for long distances than for European destinations. Domestic travel activity with overnight stay is nearly stagnating. The study furthermore shows...

  5. Long distance travel ‘today’

    DEFF Research Database (Denmark)

    Christensen, Linda

    2014-01-01

    This paper presents an overview of the Dane’s long distance travel. It is a part of the Drivers and Limits project about long distance travel. Long distance travel is in the project defined as infrequent travel with overnight stay. Danes 15-85 years-old travel in average 5.5 long distance travel...... per year og which a third is for international destinations, a third is for domestic second homes and a third are other domestic trips. However, 87% of the kilometres are for international destinations and only 4% are for domestic second homes. Travel activity is very uneven distributed with only half...... of the population having had a journey during the last three month. At the other hand 60% have travelled internationally during the last year and only 2% have never travelled abroad. The paper presents among other things how the travel activity is distributed on travel purpose and mode and how the mode choice...

  6. Producing Knowledge to Reduce Rhetorical Distance

    DEFF Research Database (Denmark)

    Kampf, Constance

    Producing Knowledge to Reduce Rhetorical Distance: Extending Identity and Engaging Mainstream Ideology via the Web Constance Kampf, Department of Research Knowledge Communication, Aarhus School of Business, Denmark McLuhan describes technologies as extensions -the wheel being an extension...

  7. LEVEL SET METHODS BASED ON DISTANCE FUNCTION

    Institute of Scientific and Technical Information of China (English)

    王德军; 唐云; 于洪川; 唐泽圣

    2003-01-01

    Some basic problems on the level set methods were discussed, such as the method used to preserve the distance function, the existence and uniqueness of solution for the level set equations. The main contribution is to prove that in a neighborhood of the initial zero level set, the level set equations with the restriction of the distance function have a unique solution, which must be the signed distance function with respect to the evolving surface. Some skillful approaches were used: Noticing that any solution for the original equation was a distance function, the original level set equations were transformed into a simpler alternative form. Moreover, since the new system was not a classical one, the system was transforned into an ordinary one, for which the implicit function method was adopted.

  8. Institutional Distance and the Internationalization Process

    DEFF Research Database (Denmark)

    Pogrebnyakov, Nicolai; Maitland, Carleen

    2011-01-01

    This paper applies the institutional lens to the internationalization process model. It updates the concept of psychic distance in the model with a recently developed, theoretically grounded construct of institutional distance. Institutions are considered simultaneously at the national and industry...... levels. It also aims to understand whether the internationalization process of service firms is different from the behavior predicted by the model, which was developed for the manufacturing context. We empirically test the model using proportional hazard analysis with 130 instances of entry and presence...... of mobile operators in Europe and South America over 13 years. Influences of regulative, normative and cognitive institutional aspects were disaggregated and shown to have differing effect on internationalization. This suggests that institutional distance is a viable alternative to other distance measures...

  9. Convergence of Distance Education and Conventional Learning ...

    African Journals Online (AJOL)

    Convergence of Distance Education and Conventional Learning: Innovations ... using various blended learning media including print, ICTs, electronic platforms, ... Admittedly, the blending of offline and online learning enhances significantly ...

  10. Project Work in Networked Distance Education

    DEFF Research Database (Denmark)

    Knudsen, Morten; Helbo, Jan; Jensen, Lars Peter

    2000-01-01

    . As the experience since then has proven this to be a very successful innovation in higher education [1], it seems to be an obvious idea also to base our new distance educations on the project study form. Traditionally, however, distance education has been characterized by one-way communication and self......-study, whereas the project study form is based on collaboration and dialogue. Consequently, successful implementation of project work in distance education requires extensive utilisation of new information and communication technology. In this paper the experiences of project work in a new Master of Industrial...... Information Technology distance education is described. The program is offered through Open University, and the students have a BSc degree or equivalent and at least 2 years of relevant professional experience - and a full-time job. The students are assumed to study 20 hours per week, half of the time being...

  11. Mahalanobis Distance Based Iterative Closest Point

    DEFF Research Database (Denmark)

    Hansen, Mads Fogtmann; Blas, Morten Rufus; Larsen, Rasmus

    2007-01-01

    the notion of a mahalanobis distance map upon a point set with associated covariance matrices which in addition to providing correlation weighted distance implicitly provides a method for assigning correspondence during alignment. This distance map provides an easy formulation of the ICP problem that permits......This paper proposes an extension to the standard iterative closest point method (ICP). In contrast to ICP, our approach (ICP-M) uses the Mahalanobis distance to align a set of shapes thus assigning an anisotropic independent Gaussian noise to each point in the reference shape. The paper introduces...... a fast optimization. Initially, the covariance matrices are set to the identity matrix, and all shapes are aligned to a randomly selected shape (equivalent to standard ICP). From this point the algorithm iterates between the steps: (a) obtain mean shape and new estimates of the covariance matrices from...

  12. A glocal distance for network comparison

    CERN Document Server

    Jurman, Giuseppe; Riccadonna, Samantha; Filosi, Michele; Furlanello, Cesare

    2012-01-01

    When comparing networks (with the same number of nodes) with direct methods, a number of possible distances is already available in literature. Among others, two of the most common families are the set of edit-like distances and the spectral distances. The functions in the former family quantitatively evaluate the differences between two networks in terms of minimum number of edit operations (with possibly different costs) transforming one network into the other, that is, deletion and insertion of links, while spectral measures relies on functions of the eigenvalues of one of the connectivity matrices of the underlying graph. A noticeable issue affecting edit distance is the fact of being local, i.e. not taking into account the global structure of the networks but only summing the contributions coming from each single link. On the other hand, spectral measures cannot distinguish isomorphic or isospectral graphs. We propose here a possible solution to overcome both issues: combining together an edit and a spec...

  13. Manifold Learning by Preserving Distance Orders.

    Science.gov (United States)

    Ataer-Cansizoglu, Esra; Akcakaya, Murat; Orhan, Umut; Erdogmus, Deniz

    2014-03-01

    Nonlinear dimensionality reduction is essential for the analysis and the interpretation of high dimensional data sets. In this manuscript, we propose a distance order preserving manifold learning algorithm that extends the basic mean-squared error cost function used mainly in multidimensional scaling (MDS)-based methods. We develop a constrained optimization problem by assuming explicit constraints on the order of distances in the low-dimensional space. In this optimization problem, as a generalization of MDS, instead of forcing a linear relationship between the distances in the high-dimensional original and low-dimensional projection space, we learn a non-decreasing relation approximated by radial basis functions. We compare the proposed method with existing manifold learning algorithms using synthetic datasets based on the commonly used residual variance and proposed percentage of violated distance orders metrics. We also perform experiments on a retinal image dataset used in Retinopathy of Prematurity (ROP) diagnosis.

  14. EXAMINING POLICY GUIDELINES FOR DISTANCE EDUCATION IN ...

    African Journals Online (AJOL)

    User

    The study reports a case of distance education policy in the Kwame Nkrumah University of Sci- ... used to obtain information from 21 purposively selected key informants in the University. Policy ... practice must contain values among which is.

  15. Professional development of distance education professionals ...

    African Journals Online (AJOL)

    Erna Kinsey

    profile of functions of ETD practitioners at distance education institutions. Firstly, the .... and studied to gain a clear understanding of existing practices at. TSA. ..... (NB: Assessment has been cited as an important function in the literature, but ...

  16. Distance learning techniques for medical informatics

    Science.gov (United States)

    Hersh, W

    2000-01-01

    A growing number of health care professionals (e.g., physicians, nurses, librarians, and administrators) desire to enhance their skills and knowledge in medical informatics. These individuals are usually in established careers with limited time as well as inability to relocate to one of the small number of health science universities which offer informatics training. As a result of inquiries about distance learning in medical informatics and a market survey which documented and detailed such interest, a distance learning program was launched by the medical informatics program at Oregon Health Sciences University (OHSU). In the 1999-2000 academic year, two graduate-level medical informatics courses in the OHSU program have been taught by distance learning. In the 2000-2001 academic year, an eight-course certificate program will be launched. Further information can be found at: http://www. ohsu.edu/bicc-informatics/distance/ PMID:11080024

  17. Distance function selection in several clustering algorithrms

    Institute of Scientific and Technical Information of China (English)

    LU Yu

    2004-01-01

    Most clustering algorithms need to describe the similarity of objects by a predefined distance function. Three distance functions which are widely used in two traditional clustering algorithms k-means and hierarchical clustering were investigated.Both theoretical analysis and detailed experimental results were given. It is shown that a distance function greatly affects clustering results and can be used to detect the outlier of a cluster by the comparison of such different results and give the shape information of clusters. In practice situation, it is suggested to use different distance function separately, compare the clustering results and pick out the "swing points". And such points may leak out more information for data analysts.

  18. Improving Pulsar Distances by Modelling Interstellar Scattering

    CERN Document Server

    Deshpande, A A

    1998-01-01

    We present here a method to study the distribution of electron density fluctuations in pulsar directions as well as to estimate pulsar distances. The method, based on a simple two-component model of the scattering medium discussed by Gwinn et al. (1993), uses scintillation & proper motion data in addition to the measurements of angular broadening & temporal broadening to solve for the model parameters, namely, the fractional distance to a discrete scatterer and the ascociated relative scattering strength. We show how this method can be used to estimate pulsar distances reliably, when the location of a discrete scatterer (e.g. an HII region), if any, is known. Considering the specific example of PSR B0736-40, we illustrate how a simple characterization of the Gum nebula region (using the data on the Vela pulsar) is possible and can be used along with the temporal broadening measurements to estimate pulsar distances.

  19. Perspectives on Group Work In Distance Learning

    OpenAIRE

    Hausstätter, Rune Sarromaa; NORDKVELLE, Yngve Troye

    2015-01-01

    Current distance education benefits greatly from educational software that makes group work possible for students who are separated in time and space. However, some students prefer distance education because they can work on their own. This paper explores how students react to expectations on behalf of the course provider to do their assignments in collaborative groups. They are seemingly both positively surprised by the challenges that group work offer, and they are less positive to the down...

  20. Unit distances and diameters in Euclidean spaces

    CERN Document Server

    Swanepoel, Konrad J

    2007-01-01

    We show that the maximum number of unit distances or of diameters in a set of n points in d-dimensional Euclidean space is attained only by specific types of Lenz constructions, for all d >= 4 and n sufficiently large, depending on d. As a corollary we determine the exact maximum number of unit distances for all even d >= 6, and the exact maximum number of diameters for all d >= 4, for all $n$ sufficiently large, depending on d.

  1. On the inversion-indel distance.

    Science.gov (United States)

    Willing, Eyla; Zaccaria, Simone; Braga, Marília D V; Stoye, Jens

    2013-01-01

    The inversion distance, that is the distance between two unichromosomal genomes with the same content allowing only inversions of DNA segments, can be computed thanks to a pioneering approach of Hannenhalli and Pevzner in 1995. In 2000, El-Mabrouk extended the inversion model to allow the comparison of unichromosomal genomes with unequal contents, thus insertions and deletions of DNA segments besides inversions. However, an exact algorithm was presented only for the case in which we have insertions alone and no deletion (or vice versa), while a heuristic was provided for the symmetric case, that allows both insertions and deletions and is called the inversion-indel distance. In 2005, Yancopoulos, Attie and Friedberg started a new branch of research by introducing the generic double cut and join (DCJ) operation, that can represent several genome rearrangements (including inversions). Among others, the DCJ model gave rise to two important results. First, it has been shown that the inversion distance can be computed in a simpler way with the help of the DCJ operation. Second, the DCJ operation originated the DCJ-indel distance, that allows the comparison of genomes with unequal contents, considering DCJ, insertions and deletions, and can be computed in linear time. In the present work we put these two results together to solve an open problem, showing that, when the graph that represents the relation between the two compared genomes has no bad components, the inversion-indel distance is equal to the DCJ-indel distance. We also give a lower and an upper bound for the inversion-indel distance in the presence of bad components.

  2. Redshift-distance relation in inhomogeneous cosmology

    CERN Document Server

    Scharf, Günter

    2015-01-01

    We continue to study a cosmological model with large-scale inhomogeneity. Working in the cosmic rest frame we determine null geodesics, redshift and area and luminosity distance. Combining the result with Hubble's law enables us to calculate the distance of the local group of galaxies from the origin where the Big Bang gas taken place. We obtain a surprisingly small value of about 2 million light years.

  3. Auditory Perception in Open Field: Distance Estimation

    Science.gov (United States)

    2013-07-01

    the distance and spaciousness estimation cues can be ambiguous (e.g., sound intensity, sound spectrum) or are fairly weak (e.g., binaural cues...Invariance in Sound Perception. Acta Psychologica Fennica 1951, 1, 9–20. Florentine, M.; Epstein, M. Ecological Loudness. Binaural Loudness Constancy...8, 145–149. 50 Lu, Y-Ch.; Cooke, M. Binaural Estimation of Sound Source Distance via the Direct-to- Reverberant Energy Ratio for Static and Moving

  4. Markets, Distance Education, and Australian Higher Education

    OpenAIRE

    2005-01-01

    The paper argues that the Australian university system is unstable. There will be significant change as government implements its reform agenda and even more radical change if it moves to new deregulation. The role of distance education in university education needs to be analyzed against this ‘market’ agenda of government in terms of characteristics of markets and market behavior. After a scan of the current role, the paper looks at two scenarios (regulated and deregulated) for distance educ...

  5. Designing legible fonts for distance reading

    DEFF Research Database (Denmark)

    Beier, Sofie

    2016-01-01

    This chapter reviews existing knowledge on distance legibility of fonts, and finds that for optimal distance reading, letters and numbers benefit from relative wide shapes, open inner counters and a large x-height; fonts should further be widely spaced, and the weight should not be too heavy or too...... light. Research also indicates that serifs on the vertical extremes improve legibility under such reading conditions....

  6. Radial Distance Estimation with Tapered Whisker Sensors.

    Science.gov (United States)

    Ahn, Sejoon; Kim, DaeEun

    2017-07-19

    Rats use their whiskers as tactile sensors to sense their environment. Active whisking, moving whiskers back and forth continuously, is one of prominent features observed in rodents. They can discriminate different textures or extract features of a nearby object such as size, shape and distance through active whisking. There have been studies to localize objects with artificial whiskers inspired by rat whiskers. The linear whisker model based on beam theory has been used to estimate the radial distance, that is, the distance between the base of the whisker and a target object. In this paper, we investigate deflection angle measurements instead of forces or moments, based on a linear tapered whisker model to see the role of tapered whiskers found in real animals. We analyze how accurately this model estimates the radial distance, and quantify the estimation errors and noise sensitivity. We also compare the linear model simulation and nonlinear numerical solutions. It is shown that the radial distance can be estimated using deflection angles at two different positions on the tapered whisker. We argue that the tapered whisker has an advantage of estimating the radial distance better, as compared to an untapered whisker, and active sensing allows that estimation without the whisker's material property and thickness or the moment at base. In addition, we investigate the potential of passive sensing for tactile localization.

  7. On distance variation effects on graphene bilayers

    Science.gov (United States)

    Naji, S.; Bhihi, M.; Labrim, H.; Belhaj, A.; Benyoussef, A.; El Kenz, A.; Loulidi, M.

    2014-06-01

    The opening of the energy gap and the total energy of the graphene-like bilayers are investigated using ab initio calculations. The studied model consists of a static single layer of graphene interacting with an extra dynamic one placed at a varying vertical distance d in the (AB) stacking arrangement. The effects of the vertical distance variation on the energy gap and the total energy of the system are discussed first. Starting from a distance around the van der Waals length, the energy gap does not depend on the vertical distance variation and the system exhibits graphene-like properties with minor deformations in the lattice size parameter and the energy dispersion behaviour around K points. However, it has been shown that the diagonal distance variation of the graphene-like bilayer modifies the electronic structure properties. This modification depends on an intermediate stacking arrangement between the (AA) and the (AB) configurations. It has been shown that the diagonal distance variation has an influence on the states of pz electrons in the (AB) arrangement and it can be explored to open the energy gap.

  8. Worms under stress: unravelling genetic complex traits through perturbation

    NARCIS (Netherlands)

    Rodriguez Sanchez, M.

    2014-01-01

    The genetic architecture of an organism could be considered ‘the most amazing piece of engineering’ existing in nature. Looking from a certain distance, the genetic complexity of an organism could be described as an immense jigsaw puzzle. As in a real jigsaw, the connection between two p

  9. Ancient split of major genetic lineages of European Black Pine

    NARCIS (Netherlands)

    Naydenov, Krassimir D.; Naydenov, Michel K.; Alexandrov, Alexander; Vasilevski, Kole; Gyuleva, Veselka; Matevski, Vlado; Nikolic, Biljana; Goudiaby, Venceslas; Bogunic, Faruk; Paitaridou, Despina; Christou, Andreas; Goia, Irina; Carcaillet, Christopher; Alcantara, Adrian Escudero; Ture, Cengiz; Gulcu, Suleyman; Peruzzi, Lorenzo; Kamary, Salim; Bojovic, Srdjan; Hinkov, Georgi; Tsarev, Anatoly

    2016-01-01

    The European Black Pine (Pinus nigra Arn.) has a long and complex history. Genetic distance and frequency analyses identified three differentiated genetic groups, which corresponded to three wide geographical areas: Westerns Mediterranean, Balkan Peninsula and Asia Minor. These groups shared comm

  10. Application of a Genetic Algorithm to Nearest Neighbour Classification

    NARCIS (Netherlands)

    Simkin, S.; Verwaart, D.; Vrolijk, H.C.J.

    2005-01-01

    This paper describes the application of a genetic algorithm to nearest-neighbour based imputation of sample data into a census data dataset. The genetic algorithm optimises the selection and weights of variables used for measuring distance. The results show that the measure of fit can be improved by

  11. Biochemical genetics in marine fisheries management and conservation

    Digital Repository Service at National Institute of Oceanography (India)

    Menezes, M.R.

    genetic distance dendrogram showing genetic relationships. Nei estimated that for local races of a species, D ranges from nearly 0 to 0.05, for subspecies D =0.02 to 0.2, and for full species D=O. I to 2.0. For genera. D is usually greater than I. 184...

  12. Worms under stress: unravelling genetic complex traits through perturbation

    NARCIS (Netherlands)

    Rodriguez Sanchez, M.

    2014-01-01

    The genetic architecture of an organism could be considered ‘the most amazing piece of engineering’ existing in nature. Looking from a certain distance, the genetic complexity of an organism could be described as an immense jigsaw puzzle. As in a real jigsaw, the connection between two p

  13. Analysis of genetic structure of white croaker using amplified ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-09-15

    Sep 15, 2009 ... The population with the highest Nei's genetic diversity and. Shannon diversity index ... fish assemblages off the coasts of China and Japan, supporting an ..... genetic distances. graphic structure of populations may be influenced by ... the sea-level-induced environmental signal was amplified in the marginal ...

  14. RNA genetics

    Energy Technology Data Exchange (ETDEWEB)

    Domingo, E. (Instituto de Biologia Molecular, Facultad de Ciencias, Universidad Autonoma de Madrid, Canto Blanco, Madrid (ES)); Holland, J.J. (California Univ., San Diego, La Jolla, CA (USA). Dept. of Biology); Ahlquist, P. (Wisconsin Univ., Madison, WI (USA). Dept. of Plant Pathology)

    1988-01-01

    This book contains the proceedings on RNA genetics: RNA-directed virus replication Volume 1. Topics covered include: Replication of the poliovirus genome; Influenza viral RNA transcription and replication; and Relication of the reoviridal: Information derived from gene cloning and expression.

  15. Genetic counseling

    Science.gov (United States)

    ... MF, eds. Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice . 7th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 30. Review Date 1/25/2016 Updated by: Chad Haldeman-Englert, MD, FACMG, Fullerton Genetics Center, Asheville, NC. Review provided by VeriMed Healthcare ...

  16. Alignment-free phylogenetics and population genetics.

    Science.gov (United States)

    Haubold, Bernhard

    2014-05-01

    Phylogenetics and population genetics are central disciplines in evolutionary biology. Both are based on comparative data, today usually DNA sequences. These have become so plentiful that alignment-free sequence comparison is of growing importance in the race between scientists and sequencing machines. In phylogenetics, efficient distance computation is the major contribution of alignment-free methods. A distance measure should reflect the number of substitutions per site, which underlies classical alignment-based phylogeny reconstruction. Alignment-free distance measures are either based on word counts or on match lengths, and I apply examples of both approaches to simulated and real data to assess their accuracy and efficiency. While phylogeny reconstruction is based on the number of substitutions, in population genetics, the distribution of mutations along a sequence is also considered. This distribution can be explored by match lengths, thus opening the prospect of alignment-free population genomics.

  17. Integrating order and distance relationships from heterogeneous maps.

    Science.gov (United States)

    Graves, M

    1993-01-01

    There is no automatic mechanism to integrate information between heterogeneous genome maps. Currently, integration is a difficult, manual process. We have developed a process for knowledge base design, and we use this to integrate order and distance relationships between genetic linkage, radiation hybrid, and physical maps. Until now, the only way to develop a persistent, knowledge-intensive application was to either develop a new knowledge base from scratch or coerce the application to fit an existing knowledge base. This was not from lack of interest by the knowledge base or database community, but merely from a lack of theoretical tools powerful enough to tackle the problem. We import formalisms from knowledge representation, natural language semantics, programming language research, and databases. These form a strong, theoretical foundation for knowledge base design upon which we have implemented the knowledge base design tool called WEAVE.

  18. Physiological vagility: correlations with dispersal and population genetic structure of amphibians.

    Science.gov (United States)

    Hillman, Stanley S; Drewes, Robert C; Hedrick, Michael S; Hancock, Thomas V

    2014-01-01

    Physiological vagility represents the capacity to move sustainably and is central to fully explaining the processes involved in creating fine-scale genetic structure of amphibian populations, because movement (vagility) and the duration of movement determine the dispersal distance individuals can move to interbreed. The tendency for amphibians to maintain genetic differentiation over relatively short distances (isolation by distance) has been attributed to their limited dispersal capacity (low vagility) compared with other vertebrates. Earlier studies analyzing genetic isolation and population differentiation with distance treat all amphibians as equally vagile and attempt to explain genetic differentiation only in terms of physical environmental characteristics. We introduce a new quantitative metric for vagility that incorporates aerobic capacity, body size, body temperature, and the cost of transport and is independent of the physical characteristics of the environment. We test our metric for vagility with data for dispersal distance and body mass in amphibians and correlate vagility with data for genetic differentiation (F'(ST)). Both dispersal distance and vagility increase with body size. Differentiation (F'(ST)) of neutral microsatellite markers with distance was inversely and significantly (R2=0.61) related to ln vagility. Genetic differentiation with distance was not significantly related to body mass alone. Generalized observations are validated with several specific amphibian studies. These results suggest that interspecific differences in physiological capacity for movement (vagility) can contribute to genetic differentiation and metapopulation structure in amphibians.

  19. Genetic diversity in the Yangtze finless porpoise by RAPD analysis

    Institute of Scientific and Technical Information of China (English)

    He Shunping; Wang Ding; Wang Wei; Chen Daoquan; Zhao Qingzhong; Gong Weiming

    2005-01-01

    To estimate the genetic diversity in the Yangtze finless porpoise (Neophocaenaphocaenoides asiaeorientalis), the randomly amplified polymorphic DNA techniquewas applied to examine ten animals captured from the Yangtze River. Out of 20 arbitrary primers used in the experiment, seventeen produced clearly reproducible bged from 0.0986 to 0.5634. Compared with other cetacean populations, this genetic distance is quite low. Such a low genetic diversity suggests that this population may be suffering from reduced genetic variation, and be very fragile. More studiesare needed for understanding the basis for this apparent low genetic diversity and to help protect this endangered, unique population.

  20. Genetic structure of nine horse populations

    Directory of Open Access Journals (Sweden)

    Monika Burócziová

    2008-01-01

    Full Text Available In the present study was estimate the genetic diversity and relationships among nine horses breeds in Czech and Slovak Republic.In conclusion, the main objective of study was to show the level of genetic distance among the horse breeds with different history of breeding of each country. Furthermore, it should be clarified whether these populations and subpopulations are distinct enough from each other to justify defining separate breeds. This research concerns the variability of microsatellite markers in genotypes of horse. We compared the genetic diversity and distance among nine horse breeds Czech and Slovak Warmblood both of Czech origin, Slovak Warmblood of Slovak origin, Hucul, Hafling, Furioso, Noriker, Silesian Noriker and Bohemian-Moravian Belgian Horse.In total, 932 animals were genotyped for 17 microsatellites markers (AHT4, AHT5, ASB2, HMS3, HMS6, HMS7, HTG4, HTG10, VHL20, HTG6, HMS2, HTG7, ASB17, ASB23, CA425, HMS1, LEX3 recommended by the International Society of Animal Genetics.In the different population size, the allele frequencies, observed and expected heterozygosity, test for deviations from Hardy-Weinberg equilibrium and Polymorphism information content have been calculated for each breed. We analyzed genetic distance and diversity among them on the base of the dataset of highly polymorphic set of microsatellites representing all autozomes using set of PowerMar­ker v3.25 analysis tools and Structure 2.2. programme for results comparison.

  1. Albatross Long-Distance Navigation: Comparing Adults And Juveniles

    Science.gov (United States)

    Åkesson, Susanne; Weimerskirch, Henri

    2005-09-01

    Albatrosses are known for their extreme navigation performance enabling them to locate isolated breeding islands after long-distance migrations across open seas. Little is known about the migration of young albatrosses and how they reach the adults' navigation and foraging skills during the period of immaturity lasting several years and spent permanently flying across the open ocean. We tracked by satellite telemetry the dispersal and migration of 13 juvenile wandering albatrosses from the Crozet Islands during their first year at sea. The young albatrosses covered an average distance of 184,000 km during the first year, restricting their dispersal movement to the unproductive and low wind subtropical Indian Ocean and Tasman Sea. The juveniles initiated the migration by an innate phase of rapid dispersal encoded as a fixed flight direction assisted by southerly winds towards north and northeast. Thereafter each individual restricted its movement to a particular zone of the ocean that will possibly be used until they start breeding 7 10 years later and return in contact with breeding adults. This dispersal in young birds corresponds well with movements observed for adult non-breeding wandering albatrosses. The results show clearly an inherited ability to navigate back to already visited areas in young wandering albatrosses. The juvenile dispersal behaviour and migration at sea suggest a genetically based migration program, encoding navigation to a destination area used throughout the life.

  2. Assessment of Genetic Diversity and Population Genetic Structure of Corylus mandshurica in China Using SSR Markers.

    Directory of Open Access Journals (Sweden)

    Jian-Wei Zong

    Full Text Available Corylus mandshurica, also known as pilose hazelnut, is an economically and ecologically important species in China. In this study, ten polymorphic simple sequence repeat (SSR markers were applied to evaluate the genetic diversity and population structure of 348 C. mandshurica individuals among 12 populations in China. The SSR markers expressed a relatively high level of genetic diversity (Na = 15.3, Ne = 5.6604, I = 1.8853, Ho = 0.6668, and He = 0.7777. According to the coefficient of genetic differentiation (Fst = 0.1215, genetic variation within the populations (87.85% were remarkably higher than among populations (12.15%. The average gene flow (Nm = 1.8080 significantly impacts the genetic structure of C. mandshurica populations. The relatively high gene flow (Nm = 1.8080 among wild C. mandshurica may be caused by wind-pollinated flowers, highly nutritious seeds and self-incompatible mating system. The UPGMA (unweighted pair group method of arithmetic averages dendrogram was divided into two main clusters. Moreover, the results of STRUCTURE analysis suggested that C. mandshurica populations fell into two main clusters. Comparison of the UPGMA dendrogram and the Bayesian STRUCTURE analysis showed general agreement between the population subdivisions and the genetic relationships among populations of C. mandshurica. Group I accessions were located in Northeast China, while Group II accessions were in North China. It is worth noting that a number of genetically similar populations were located in the same geographic region. The results further showed that there was obvious genetic differentiation among populations from Northeast China to North China. Results from the Mantel test showed a weak but still significant positive correlation between Nei's genetic distance and geographic distance (km among populations (r = 0.419, P = 0.005, suggesting that genetic differentiation in the 12 C. mandshurica populations might be related to geographic

  3. Averaging of random sets based on their distance functions

    NARCIS (Netherlands)

    Baddeley, A.J.; Molchanov, I.S.

    1995-01-01

    A new notion of expectation (or distance average) of random closed sets based on their distance function representation is introduced. A general concept of the distance function is exploited to define the expectation, which is the set whose distance function is closest to the expected distance funct

  4. A Foundation for Efficient Indoor Distance-Aware Query Processing

    DEFF Research Database (Denmark)

    Lu, Hua; Cao, Xin; Jensen, Christian Søndergaard

    2012-01-01

    indoor distances. However, existing indoor space models do not account well for indoor distances. To address this shortcoming, we propose a data management infrastructure that captures indoor distance and facilitates distance-aware query processing. In particular, we propose a distance-aware indoor space...

  5. 14 CFR 25.113 - Takeoff distance and takeoff run.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Takeoff distance and takeoff run. 25.113... and takeoff run. (a) Takeoff distance on a dry runway is the greater of— (1) The horizontal distance... include a clearway, the takeoff run is equal to the takeoff distance. If the takeoff distance includes...

  6. Estimating Distances from Parallaxes. III. Distances of Two Million Stars in the Gaia DR1 Catalogue

    Science.gov (United States)

    Astraatmadja, Tri L.; Bailer-Jones, Coryn A. L.

    2016-12-01

    We infer distances and their asymmetric uncertainties for two million stars using the parallaxes published in the Gaia DR1 (GDR1) catalogue. We do this with two distance priors: A minimalist, isotropic prior assuming an exponentially decreasing space density with increasing distance, and an anisotropic prior derived from the observability of stars in a Milky Way model. We validate our results by comparing our distance estimates for 105 Cepheids which have more precise, independently estimated distances. For this sample we find that the Milky Way prior performs better (the rms of the scaled residuals is 0.40) than the exponentially decreasing space density prior (rms is 0.57), although for distances beyond 2 kpc the Milky Way prior performs worse, with a bias in the scaled residuals of -0.36 (versus -0.07 for the exponentially decreasing space density prior). We do not attempt to include the photometric data in GDR1 due to the lack of reliable color information. Our distance catalog is available at http://www.mpia.de/homes/calj/tgas_distances/main.html as well as at CDS. This should only be used to give individual distances. Combining data or testing models should be done with the original parallaxes, and attention paid to correlated and systematic uncertainties.

  7. Absolute Orientation Based on Distance Kernel Functions

    Directory of Open Access Journals (Sweden)

    Yanbiao Sun

    2016-03-01

    Full Text Available The classical absolute orientation method is capable of transforming tie points (TPs from a local coordinate system to a global (geodetic coordinate system. The method is based only on a unique set of similarity transformation parameters estimated by minimizing the total difference between all ground control points (GCPs and the fitted points. Nevertheless, it often yields a transformation with poor accuracy, especially in large-scale study cases. To address this problem, this study proposes a novel absolute orientation method based on distance kernel functions, in which various sets of similarity transformation parameters instead of only one set are calculated. When estimating the similarity transformation parameters for TPs using the iterative solution of a non-linear least squares problem, we assigned larger weighting matrices for the GCPs for which the distances from the point are short. The weighting matrices can be evaluated using the distance kernel function as a function of the distances between the GCPs and the TPs. Furthermore, we used the exponential function and the Gaussian function to describe distance kernel functions in this study. To validate and verify the proposed method, six synthetic and two real datasets were tested. The accuracy was significantly improved by the proposed method when compared to the classical method, although a higher computational complexity is experienced.

  8. Constraining the Correlation Distance in Quantum Measurements

    CERN Document Server

    Schneider, Jean

    2010-01-01

    Standard Quantum Physics states that the outcome of measurements for some distant entangled subsystems are instantaneously statistically correlated, whatever their mutual distance. This correlation presents itself as if there were a correlation at a distance with infinite speed. It is expressed by the Bell Theorem. It has been experimentally verified over distances up to 18 km with a time resolution of a few picosecond, which can be translated into an apparent effective correlation speed larger than 10^7 c. The purpose of the present White Paper is to discuss the scientific interest and the feasibility to extend the correlation distance up to the Earth-Moon distance, i.e. 2 10^4 times larger than in present experiments. We are thus led to propose to install on the Moon a polarimter and a high performance photon detector with a high temporal resolution. Such an exploratory experiment would provide new tests of Quantum Physics and could perhaps discriminate between standard Quantum Physics and for instance the ...

  9. INVESTIGATING DISTANCE EDUCATION STUDENTS’ STUDY SKILLS

    Directory of Open Access Journals (Sweden)

    Cengiz POYRAZ

    2013-10-01

    Full Text Available Distance education, which is a planned way of teaching in which students and instructors are brought face to face in a classroom environment in several different ways by means of technology, has started to become widespread in many fields today. In distance education, students and instructors reside in different locations. Students can learn at their pace and control their learning path, content and load of what they have learned and evaluate it. However, they should adopt strategies for effective studying in order not to waste their time and efforts. Because study skills, motivation, time management, exam preparation and coping with exam stress have an impact on students’ success. In this context, distance education students’ study skills are foregrounded in today’s widespread use of distance education. In accordance with this, this study aims to investigate some variables which are influential on the dimensions of distance education students’ motivation, time management, exam preparation and coping with exam stress. A personal information form and the Study Skills scale were used for data collection. This study was designed in survey model and SPSS16.0 statistical package program was used for the statistical analyses of the research data. The research findings were discussed in line with the literature and some suggestions were presented for further research and researchers.

  10. A NEW METHOD FOR MEASURING EXTRAGALACTIC DISTANCES

    Energy Technology Data Exchange (ETDEWEB)

    Yoshii, Yuzuru; Minezaki, Takeo [Institute of Astronomy, School of Science, University of Tokyo, 2-21-1 Osawa, Mitaka, Tokyo 181-0015 (Japan); Kobayashi, Yukiyasu [National Astronomical Observatory, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Koshida, Shintaro [Center of Astro Engineering and Department of Electrical Engineering, Pontificia Univercsidad Catolica de Chile, Av. Vicuna Mackenna 4868 (Chile); Peterson, Bruce A., E-mail: yoshii@ioa.s.u-tokyo.ac.jp [Mount Stromlo Observatory, Research School of Astronomy and Astrophysics, Australian National University, Weston Creek P.O., ACT 2611 (Australia)

    2014-03-20

    We have pioneered a new method for the measurement of extragalactic distances. This method uses the time lag between variations in the short wavelength and long wavelength light from an active galactic nucleus (AGN), based on a quantitative physical model of dust reverberation that relates the time lag to the absolute luminosity of the AGN. We use the large homogeneous data set from intensive monitoring observations in optical and near-infrared wavelength bands with the dedicated 2 m MAGNUM telescope to obtain the distances to 17 AGNs in the redshift range z = 0.0024 to z = 0.0353. These distance measurements are compared with distances measured using Cepheid variable stars, and are used to infer that H {sub 0} = 73 ± 3 (random) km s{sup –1} Mpc{sup –1}. The systematic error in H {sub 0} is examined, and the uncertainty in the size distribution of dust grains is the largest source of the systematic error, which is much reduced for a sample of AGNs for which their parameter values in the model of dust reverberation are individually measured. This AGN time lag method can be used beyond 30 Mpc, the farthest distance reached by extragalactic Cepheids, and can be extended to high-redshift quasi-stellar objects.

  11. KINEMATIC DISTANCE ASSIGNMENTS WITH H I ABSORPTION

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Courtney; Dickey, John M. [School of Mathematics and Physics, Private Bag 37, University of Tasmania, Hobart 7000 (Australia)

    2012-07-01

    Using H I absorption spectra from the International Galactic Plane Survey, a new method is implemented to resolve the kinematic distance ambiguity for 75 H II regions with known systemic velocities from radio recombination lines. A further 40 kinematic distance determinations are made for H II region candidates without known systemic velocities through an investigation of the presence of H I absorption around the terminal velocity. New kinematic distance determinations can be used to further constrain spiral arm parameters and the location and extent of other structures in the Milky Way disk. H I absorption toward continuum sources beyond the solar circle is also investigated. Follow-up studies of H I at higher resolution than the 1' to 2' of existing Galactic Plane Surveys will provide kinematic distances to many more H II regions on the far side of the Galactic center. On the basis of the velocity channel summation technique developed in this paper, a much larger sample of H II regions will be analyzed in a future paper to remove the near-far distance ambiguity.

  12. Refocusing distance of a standard plenoptic camera.

    Science.gov (United States)

    Hahne, Christopher; Aggoun, Amar; Velisavljevic, Vladan; Fiebig, Susanne; Pesch, Matthias

    2016-09-19

    Recent developments in computational photography enabled variation of the optical focus of a plenoptic camera after image exposure, also known as refocusing. Existing ray models in the field simplify the camera's complexity for the purpose of image and depth map enhancement, but fail to satisfyingly predict the distance to which a photograph is refocused. By treating a pair of light rays as a system of linear functions, it will be shown in this paper that its solution yields an intersection indicating the distance to a refocused object plane. Experimental work is conducted with different lenses and focus settings while comparing distance estimates with a stack of refocused photographs for which a blur metric has been devised. Quantitative assessments over a 24 m distance range suggest that predictions deviate by less than 0.35 % in comparison to an optical design software. The proposed refocusing estimator assists in predicting object distances just as in the prototyping stage of plenoptic cameras and will be an essential feature in applications demanding high precision in synthetic focus or where depth map recovery is done by analyzing a stack of refocused photographs.

  13. Stochastic model updating using distance discrimination analysis

    Institute of Scientific and Technical Information of China (English)

    Deng Zhongmin; Bi Sifeng; Sez Atamturktur

    2014-01-01

    This manuscript presents a stochastic model updating method, taking both uncertainties in models and variability in testing into account. The updated finite element (FE) models obtained through the proposed technique can aid in the analysis and design of structural systems. The authors developed a stochastic model updating method integrating distance discrimination analysis (DDA) and advanced Monte Carlo (MC) technique to (1) enable more efficient MC by using a response surface model, (2) calibrate parameters with an iterative test-analysis correlation based upon DDA, and (3) utilize and compare different distance functions as correlation metrics. Using DDA, the influence of distance functions on model updating results is analyzed. The proposed sto-chastic method makes it possible to obtain a precise model updating outcome with acceptable cal-culation cost. The stochastic method is demonstrated on a helicopter case study updated using both Euclidian and Mahalanobis distance metrics. It is observed that the selected distance function influ-ences the iterative calibration process and thus, the calibration outcome, indicating that an integra-tion of different metrics might yield improved results.

  14. Validity of Self-Reported Running Distance.

    Science.gov (United States)

    Dideriksen, Mette; Soegaard, Cristina; Nielsen, Rasmus O

    2016-06-01

    It is unclear whether there is a difference between subjective evaluation and objective global positioning systems (GPS) measurement of running distance. The purpose of this study was to investigate if such difference exists. A total of 100 participants (51% men; median age, 41.5; body mass, 78.1 kg ±13.8 SD) completed a run of free choice, then subjectively reported the distance in kilometer (km). This information was subsequently compared with the distance derived from a nondifferential GPS watch using paired t-tests and Bland-Altman's 95% limits of agreement. No significant difference was found between the mean paired differences between subjective evaluations and GPS measurements (1.86%, 95% confidence interval = -1.53%; 5.25%, p = 0.96). The Bland-Altman 95% limits of agreement revealed considerable variation (lower limit = -28% and upper limit = 40%). Such variation exceeds the clinical error range of 10%. In conclusion, the mean running distance (km) is similar between self-reporting and GPS measurements. However, researchers should consider using GPS measurements in favor of subjective reporting of running distance because of considerable variation on an individual level.

  15. Genetic divergence among pumpkin landraces

    Directory of Open Access Journals (Sweden)

    Rebeca Lourenço de Oliveira

    2016-04-01

    Full Text Available Estimating the genetic variability in germplasm collections is important not only for conserving genetic resources, but also for plant breeding purposes. However, generating a large number of different categories data (qualitative and quantitative often complicate the analysis and results interpretation, resulting in an incomplete distinction of accessions. This study reports the characterization and evaluation of 14 pumpkin (Cucurbita moschata accessions collected from farms in the northern region of Rio de Janeiro state. Genetic diversity among accessions was also estimated using qualitative and quantitative variables considering joint analysis. The plants were grown under field conditions in a randomized block design with three replications and six plants per plot. Eight qualitative traits (leaf size; seed shape; seed color; color of the fruit pulp; hollow; fruit shape; skin color, and fruit skin texture and eight quantitative traits (fruit weight; fruit length; fruit diameter; soluble solids, 100 seed weight, and wall thickness measured in the middle and in the lower stem were evaluated. The data were analyzed considering the Gower distance, and cluster analysis was performed using unweighted pair group method with arithmetic mean (UPGMA. Variability among accessions was observed considering morphoagronomic data. The Gower distance together with UPGMA cluster allowed for good discrimination between accessions in the groups, demonstrating that the simultaneous analysis of qualitative and quantitative data is feasible and may increase the understanding of the variation among accessions.

  16. Long-distance seed dispersal by straw-coloured fruit bats varies by season and landscape

    Directory of Open Access Journals (Sweden)

    Michael Abedi-Lartey

    2016-07-01

    Full Text Available On-going fragmentation of tropical forest ecosystems and associated depletion of seed dispersers threatens the long-term survival of animal-dispersed plants. These threats do not only affect biodiversity and species abundance, but ultimately ecosystem functions and services. Thus, seed dispersers such as the straw-coloured fruit bat, E. helvum, which traverse long distances across fragmented landscapes, are particularly important for maintaining genetic connectivity and colonizing new sites for plant species. Using high-resolution GPS-tracking of movements, field observations and gut retention experiments, we quantify dispersal distances for small- and large-seeded fruits foraged by E. helvum during periods of colony population low (wet season and high (dry season in an urban and a rural landscape in the forest zone of Ghana. Gut passage time averaged 116 min (range 4–1143 min, comparable to other fruit bats. Movements were generally longer in the urban than in the rural landscape and also longer in the dry than in the wet season. As the majority of seeds are dispersed only to feeding roosts, median dispersal distances were similar for both large (42–67 m and small (42–65 m seeds. However, small seeds were potentially dispersed up to 75.4 km, four times further than the previous maximum distance estimated for a similar-sized frugivore. Maximum seed dispersal distances for small seeds were almost twice as long in the rural (49.7 km compare to the urban (31.2 km landscape. Within the urban landscape, estimated maximum dispersal distances for small seeds were three times longer during the dry season (75.4 km compared to the wet season (22.8 km; in contrast, distances in the rural landscape were three times longer in the wet season (67 km compared to the dry season (24.4. Dispersal distances for large seeds during the dry season (551 m in the rural landscape were almost twice that in the wet season (319 m. We found no influence of food

  17. Melanoma genetics

    DEFF Research Database (Denmark)

    Read, Jazlyn; Wadt, Karin A W; Hayward, Nicholas K

    2016-01-01

    Approximately 10% of melanoma cases report a relative affected with melanoma, and a positive family history is associated with an increased risk of developing melanoma. Although the majority of genetic alterations associated with melanoma development are somatic, the underlying presence...... of heritable melanoma risk genes is an important component of disease occurrence. Susceptibility for some families is due to mutation in one of the known high penetrance melanoma predisposition genes: CDKN2A, CDK4, BAP1, POT1, ACD, TERF2IP and TERT. However, despite such mutations being implicated...... in a combined total of approximately 50% of familial melanoma cases, the underlying genetic basis is unexplained for the remainder of high-density melanoma families. Aside from the possibility of extremely rare mutations in a few additional high penetrance genes yet to be discovered, this suggests a likely...

  18. Distance Duality Relation from Strong Gravitational Lensing

    CERN Document Server

    Liao, Kai; Cao, Shuo; Biesiada, Marek; Zheng, Xiaogang; Zhu, Zong-Hong

    2015-01-01

    Under very general assumptions of metric theory of spacetime, photons traveling along null geodesics and photon number conservation, two observable concepts of cosmic distance, i.e. the angular diameter and the luminosity distances are related to each other by the so called distance duality relation (DDR) $D^L=D^A(1+z)^2$. Observational validation of this relation is quite important because any evidence of its violation could be a signal of new physics. In this letter we introduce a new method to test DDR based on strong gravitational lensing systems and supernovae Ia. Using a new compilation of strong lensing systems and JLA compilation of SNe Ia we found no evidence of DDR violation. However, not so much the final result but the method itself is worth attention, because unlike previously proposed techniques, it does not depend on prior assumptions concerning the details of cosmological model and galaxy cluster modelling.

  19. Optimal architectures for long distance quantum communication.

    Science.gov (United States)

    Muralidharan, Sreraman; Li, Linshu; Kim, Jungsang; Lütkenhaus, Norbert; Lukin, Mikhail D; Jiang, Liang

    2016-02-15

    Despite the tremendous progress of quantum cryptography, efficient quantum communication over long distances (≥ 1000 km) remains an outstanding challenge due to fiber attenuation and operation errors accumulated over the entire communication distance. Quantum repeaters (QRs), as a promising approach, can overcome both photon loss and operation errors, and hence significantly speedup the communication rate. Depending on the methods used to correct loss and operation errors, all the proposed QR schemes can be classified into three categories (generations). Here we present the first systematic comparison of three generations of quantum repeaters by evaluating the cost of both temporal and physical resources, and identify the optimized quantum repeater architecture for a given set of experimental parameters for use in quantum key distribution. Our work provides a roadmap for the experimental realizations of highly efficient quantum networks over transcontinental distances.

  20. Length and distance on a quantum space

    CERN Document Server

    Martinetti, Pierre

    2012-01-01

    This contribution is an introduction to the metric aspect of noncommutative geometry, with emphasize on the Moyal plane. Starting by questioning "how to define a standard meter in a space whose coordinates no longer commute?", we list several recent results regarding Connes's spectral distance calculated between eigenstates of the quantum harmonic oscillator arXiv:0912.0906, as well as between coherent states arXiv:1110.6164. We also question the difference (which remains hidden in the commutative case) between the spectral distance and the notion of quantum length inherited from the length operator defined in various models of noncommutative space-time (DFR and \\theta-Minkowski). We recall that a standard procedure in noncommutative geometry, consisting in doubling the spectral triple, allows to fruitfully confront the spectral distance with the quantum length. Finally we refine the idea of discrete vs. continuous geodesics in the Moyal plane, introduced in arXiv:1106.0261.

  1. Spectral Clustering with Local Projection Distance Measurement

    Directory of Open Access Journals (Sweden)

    Chen Diao

    2015-01-01

    Full Text Available Constructing a rational affinity matrix is crucial for spectral clustering. In this paper, a novel spectral clustering via local projection distance measure (LPDM is proposed. In this method, the Local-Projection-Neighborhood (LPN is defined, which is a region between a pair of data, and other data in the LPN are projected onto the straight line among the data pairs. Utilizing the Euclidean distance between projective points, the local spatial structure of data can be well detected to measure the similarity of objects. Then the affinity matrix can be obtained by using a new similarity measurement, which can squeeze or widen the projective distance with the different spatial structure of data. Experimental results show that the LPDM algorithm can obtain desirable results with high performance on synthetic datasets, real-world datasets, and images.

  2. A note on the injection distance

    DEFF Research Database (Denmark)

    Bulygin, Stanislav; Geil, Hans Olav; Ruano Benito, Diego

    2009-01-01

    . Recently, Silva and Kschischang introduced in [D. Silva and F.R. Kschischang, "On Metrics for Error Correction in Network Coding," To appear in IEEE Trans. Inform. Theory, ArXiv: 0805.3824v4[cs.IT], 2009] the injection distance to give a detailed picture of what happens in noncoherent network coding. We......Koetter and Kschischang showed in [R. Koetter and F.R. Kschischang, "Coding for Errors and Erasures in Random Network Coding," IEEE Trans. Inform. Theory, {54(8), 2008] that the network coding counterpart of Gabidulin codes performs asymptotically optimal with respect to the subspace distance...... show that the above codes are also asymptotically optimal with respect to this distance....

  3. Distance dependence of fluorescence resonance energy transfer

    Indian Academy of Sciences (India)

    R S Swathi; K L Sebastian

    2009-09-01

    Deviations from the usual -6 dependence of the rate of fluorescence resonance energy transfer (FRET) on the distance between the donor and the acceptor have been a common scenario in the recent times. In this paper, we present a critical analysis of the distance dependence of FRET, and try to illustrate the non--6 type behaviour of the rate for the case of transfer from a localized electronic excitation on the donor, a dye molecule to three different energy acceptors with delocalized electronic excitations namely, graphene, a two-dimensional semiconducting sheet and the case of such a semiconducting sheet rolled to obtain a nanotube. We use simple analytic models to understand the distance dependence in each case.

  4. Distance-Based Opportunistic Mobile Data Offloading

    Science.gov (United States)

    Lu, Xiaofeng; Lio, Pietro; Hui, Pan

    2016-01-01

    Cellular network data traffic can be offload onto opportunistic networks. This paper proposes a Distance-based Opportunistic Publish/Subscribe (DOPS) content dissemination model, which is composed of three layers: application layer, decision-making layer and network layer. When a user wants new content, he/she subscribes on a subscribing server. Users having the contents decide whether to deliver the contents to the subscriber based on the distance information. If in the meantime a content owner has traveled further in the immediate past time than the distance between the owner and the subscriber, the content owner will send the content to the subscriber through opportunistic routing. Simulations provide an evaluation of the data traffic offloading efficiency of DOPS. PMID:27314361

  5. Scenario Crisis Cases in Distance Learning Sessions

    Science.gov (United States)

    Antunes, A.

    2013-04-01

    We discuss early results using student-lead role-play of crises and disaster scenarios to encourage engagement in distance learning sessions. The disadvantage of distance learning via web interface—the lack of face-to-face and the ease with which a student can remain quiet—is balanced by the wealth of Internet-accessible media reports of past mission disasters. Capitol College minimizes the lecture component to simply frame each session's open-ended crisis in our Mission Operations engineering course. The students are presented with a historical ‘disaster’ but not its resolution; they present their course of action, then the lecturer steps in to debrief. With a wealth of past cases available on the web, use of scenarios rather than lectures shows early signs of being viable model for encouraging discussion and interaction within distance learning for a variety of course topics.

  6. Estimating shot distance from limited pellets pattern.

    Science.gov (United States)

    Plebe, Alessio; Compagnini, Domenico

    2012-10-10

    Several methods are available for shooting range estimation based on pellets pattern on the target that have a remarkable degree of accuracy. The task is usually approached working under the assumption that the entire distribution of pellets is available for examination. These methods fail, however, when the victim has been hit by a portion of the pattern only. The problem can be solved with reasonable accuracy when there are areas of void in the victim that are adjacent to the area struck by pellets. This study presents a method that can be used in precisely this type of situation, allowing the estimation of shot distance in cases of partial pellet patterns. It is based on collecting distributions in test shots at several distances, and taking samples in the targets, constrained by the shape of the void and the pellet hit areas. Statistical descriptors of patterns are extracted from such samples, and fed into a neural network classifier, estimating shot ranges of distance.

  7. Short distance behaviour of the effective string

    CERN Document Server

    Caselle, M; Panero, M

    2004-01-01

    We study the Polyakov loop correlator in the (2+1) dimensional Z_2 gauge model. A novel algorithm that we have presented recently, allows us to reach high precision results for a large range of distances and temperatures, giving us a unique opportunity to test predictions of the effective Nambu-Goto string model. Here we focus on the regime of low temperatures and small distances. In contrast to the high temperature, large distance regime, we find that our numerical results are not well described by the two loop-prediction of the Nambu-Goto model. In addition we compare our data with those for the SU(2) and SU(3) gauge models in (2+1) dimensions obtained by other authors. We generalize the result of Luscher and Weisz for a boundary term in the interquark potential to the finite temperature case.

  8. [Panorama of nursing distance education in Brazil].

    Science.gov (United States)

    Rojo, Priscila Tagliaferro; Vieira, Sheila de Souza; Zem-Mascarenhas, Silvia Helena; Sandor, Elisane Regina; Vieira, Carla Roberta Sola de Paula

    2011-12-01

    The development of distance education is associated with the popularization and democratization of the accessibility to information and communication technologies. Nursing has been using this modality of education in both undergraduate and graduate courses, which has provided knowledge about other technologies, an easier accessibility, flexibility of time and space, and reduced costs. The objective of this study is map the national higher education distance nursing courses. This exploratory, descriptive study was developed by visiting governmental, non-governmental and institutional websites. Two undergraduate and nine graduate courses in nursing were found, which is considered to be a low number, considering that distance education is an appropriate pedagogical tool that permits to prepare a large number of nurses who are geographically dispersed and who do not have access to the conventional educational processes.

  9. The social distance theory of power.

    Science.gov (United States)

    Magee, Joe C; Smith, Pamela K

    2013-05-01

    We propose that asymmetric dependence between individuals (i.e., power) produces asymmetric social distance, with high-power individuals feeling more distant than low-power individuals. From this insight, we articulate predictions about how power affects (a) social comparison, (b) susceptibility to influence, (c) mental state inference and responsiveness, and (d) emotions. We then explain how high-power individuals' greater experienced social distance leads them to engage in more abstract mental representation. This mediating process of construal level generates predictions about how power affects (a) goal selection and pursuit, (b) attention to desirability and feasibility concerns, (c) subjective certainty, (d) value-behavior correspondence, (e) self-control, and (f) person perception. We also reassess the approach/inhibition theory of power, noting limitations both in what it can predict and in the evidence directly supporting its proposed mechanisms. Finally, we discuss moderators and methodological recommendations for the study of power from a social distance perspective.

  10. Optimal architectures for long distance quantum communication

    Science.gov (United States)

    Muralidharan, Sreraman; Li, Linshu; Kim, Jungsang; Lütkenhaus, Norbert; Lukin, Mikhail D.; Jiang, Liang

    2016-02-01

    Despite the tremendous progress of quantum cryptography, efficient quantum communication over long distances (≥1000 km) remains an outstanding challenge due to fiber attenuation and operation errors accumulated over the entire communication distance. Quantum repeaters (QRs), as a promising approach, can overcome both photon loss and operation errors, and hence significantly speedup the communication rate. Depending on the methods used to correct loss and operation errors, all the proposed QR schemes can be classified into three categories (generations). Here we present the first systematic comparison of three generations of quantum repeaters by evaluating the cost of both temporal and physical resources, and identify the optimized quantum repeater architecture for a given set of experimental parameters for use in quantum key distribution. Our work provides a roadmap for the experimental realizations of highly efficient quantum networks over transcontinental distances.

  11. Spatial genetic structure of a symbiotic beetle-fungal system: toward multi-taxa integrated landscape genetics.

    Directory of Open Access Journals (Sweden)

    Patrick M A James

    Full Text Available Spatial patterns of genetic variation in interacting species can identify shared features that are important to gene flow and can elucidate co-evolutionary relationships. We assessed concordance in spatial genetic variation between the mountain pine beetle (Dendroctonus ponderosae and one of its fungal symbionts, Grosmanniaclavigera, in western Canada using neutral genetic markers. We examined how spatial heterogeneity affects genetic variation within beetles and fungi and developed a novel integrated landscape genetics approach to assess reciprocal genetic influences between species using constrained ordination. We also compared landscape genetic models built using Euclidean distances based on allele frequencies to traditional pair-wise Fst. Both beetles and fungi exhibited moderate levels of genetic structure over the total study area, low levels of structure in the south, and more pronounced fungal structure in the north. Beetle genetic variation was associated with geographic location while that of the fungus was not. Pinevolume and climate explained beetle genetic variation in the northern region of recent outbreak expansion. Reciprocal genetic relationships were only detectedin the south where there has been alonger history of beetle infestations. The Euclidean distance and Fst-based analyses resulted in similar models in the north and over the entire study area, but differences between methods in the south suggest that genetic distances measures should be selected based on ecological and evolutionary contexts. The integrated landscape genetics framework we present is powerful, general, and can be applied to other systems to quantify the biotic and abiotic determinants of spatial genetic variation within and among taxa.

  12. Regularisation of 3D Signed Distance Fields

    DEFF Research Database (Denmark)

    Paulsen, Rasmus Reinhold; Bærentzen, Jakob Andreas; Larsen, Rasmus

    2009-01-01

    Signed 3D distance fields are used a in a variety of domains. From shape modelling to surface registration. They are typically computed based on sampled point sets. If the input point set contains holes, the behaviour of the zero-level surface of the distance field is not well defined...... Cholesky factorisation. It is demonstrated that the zero-level surface will act as a membrane after the proposed regularisation. This effectively closes holes in a predictable way. Finally, the performance of the method is tested with a set of synthetic point clouds of increasing complexity....

  13. Contextual Distance Refining for Image Retrieval

    KAUST Repository

    Islam, Almasri

    2014-09-16

    Recently, a number of methods have been proposed to improve image retrieval accuracy by capturing context information. These methods try to compensate for the fact that a visually less similar image might be more relevant because it depicts the same object. We propose a new quick method for refining any pairwise distance metric, it works by iteratively discovering the object in the image from the most similar images, and then refine the distance metric accordingly. Test show that our technique improves over the state of art in terms of accuracy over the MPEG7 dataset.

  14. Human recognition at a distance in video

    CERN Document Server

    Bhanu, Bir

    2010-01-01

    Most biometric systems employed for human recognition require physical contact with, or close proximity to, a cooperative subject. Far more challenging is the ability to reliably recognize individuals at a distance, when viewed from an arbitrary angle under real-world environmental conditions. Gait and face data are the two biometrics that can be most easily captured from a distance using a video camera. This comprehensive and logically organized text/reference addresses the fundamental problems associated with gait and face-based human recognition, from color and infrared video data that are

  15. Normalized Information Distance is Not Semicomputable

    CERN Document Server

    Terwijn, Sebastiaan A; Vitanyi, Paul M B

    2010-01-01

    Normalized information distance (NID) uses the theoretical notion of Kolmogorov complexity, which for practical purposes is approximated by the length of the compressed version of the file involved, using a real-world compression program. This practical application is called 'normalized compression distance' and it is trivially computable. It is a parameter-free similarity measure based on compression, and is used in pattern recognition, data mining, phylogeny, clustering, and classification. The complexity properties of its theoretical precursor, the NID, have been open. We show that the NID is neither upper semicomputable nor lower semicomputable.

  16. Nonapproximablity of the Normalized Information Distance

    CERN Document Server

    Terwijn, Sebastiaan A; Vitanyi, Paul M B

    2009-01-01

    Normalized information distance (NID) uses the theoretical notion of Kolmogorov complexity, which for practical purposes is approximated by the length of the compressed version of the file involved, using a real-world compression program. This practical application is called `normalized compression distance' and it is trivially computable. It is a parameter-free similarity measure based on compression, and is used in pattern recognition, data mining, phylogeny, clustering, and classification. The complexity properties of its theoretical precursor, the NID, have been open. We show that the NID is neither upper semicomputable nor lower semicomputable up to any reasonable precision.

  17. An Introduction to Distance Measurement in Astronomy

    CERN Document Server

    de Grijs, Richard

    2011-01-01

    Distance determination is an essential technique in astronomy, and is briefly covered in most textbooks on astrophysics and cosmology. It is rarely covered as a coherent topic in its own right. When it is discussed the approach is frequently very dry, splitting the teaching into, for example, stars, galaxies and cosmologies, and as a consequence, books lack depth and are rarely comprehensive. Adopting a unique and engaging approach to the subject An Introduction to distance Measurement in Astronomy will take the reader on a journey from the solar neighbourhood to the edge of the Universe, dis

  18. PERSPECTIVES ON GROUP WORK IN DISTANCE LEARNING

    Directory of Open Access Journals (Sweden)

    Rune Sarromaa HAUSSTÄTTER

    2007-01-01

    Full Text Available Current distance education benefits greatly from educational software that makes group work possible for students who are separated in time and space. However, some students prefer distance education because they can work on their own. This paper explores how students react to expectations on behalf of the course provider to do their assignments in collaborative groups. They are seemingly both positively surprised by the challenges that group work offer, and they are less positive to the downsides of group work. The paper discusses both sides of the experiences and suggests why this might be a paradox to live with.

  19. Explorations in Physics and Distance Learning

    Science.gov (United States)

    Caviness, Kenneth

    2010-02-01

    How can the activity-based directed inquiry model be applied in a distance learning class? Lessons learned during a two-year pilot program (2007-2009) using the ``Explorations in Physics'' curriculum (David P. Jackson, Priscilla W. Laws, Scott V. Franklin) for a class taught over the internet using VCAM technology. The author reports on the successes, difficulties and surprises of teaching an exploratory physics class at a distance, where teacher-student interaction occurred via high-definition camera and big screen, two-way sight and sound carried by high-speed internet. )

  20. Short-Distance Structure of Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Douglas Higinbotham, Eliazer Piasetzky, Stephen Wood

    2011-06-01

    One of Jefferson Lab's original missions was to further our understanding of the short-distance structure of nuclei. In particular, to understand what happens when two or more nucleons within a nucleus have strongly overlapping wave-functions; a phenomena commonly referred to as short-range correlations. Herein, we review the results of the (e,e'), (e,e'p) and (e,e'pN) reactions that have been used at Jefferson Lab to probe this short-distance structure as well as provide an outlook for future experiments.

  1. DISTANCE FORMAT OF PSYCHOLOGICAL COMPETENCIES DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Yunona M. Ilina

    2010-08-01

    Full Text Available The paper is focused on the conceptual model of the distance learning course (DLC “Success” aimed at the development of psychological competencies. The course was developed on the basis of design technology method and intended for adults that are in need of psychological competencies development, i.e. inhabitants of villages, towns, people with special needs, university faculty, trainers and social workers, educators, who want to use DLC in the process of psychological competencies development that are the result in enhancement of life quality. The structure of the distance learning course “Success” and underlying principles is described.

  2. Robustness of Distance-to-Default

    DEFF Research Database (Denmark)

    Jessen, Cathrine; Lando, David

    2015-01-01

    Distance-to-default (DD) is a measure of default risk derived from observed stock prices and book leverage using the structural credit risk model of Merton (1974). Despite the simplifying assumptions that underlie its derivation, DD has proven empirically to be a strong predictor of default. We use...... is successful in ranking firms’ default probabilities, even if the underlying model assumptions are altered. A possibility of large jumps in asset value or stochastic volatility challenge the robustness of DD. We propose a volatility adjustment of the distance-to-default measure that significantly improves...... the ranking of firms with stochastic volatility, but this measure is less robust to model misspecifications than DD....

  3. Markets, Distance Education, and Australian Higher Education

    Directory of Open Access Journals (Sweden)

    Ted Nunan

    2005-03-01

    Full Text Available The paper argues that the Australian university system is unstable. There will be significant change as government implements its reform agenda and even more radical change if it moves to new deregulation. The role of distance education in university education needs to be analyzed against this ‘market’ agenda of government in terms of characteristics of markets and market behavior. After a scan of the current role, the paper looks at two scenarios (regulated and deregulated for distance education in university teaching and learning in Australia.

  4. Genetic Differences of Mitten Crabs Based on RFLP Analysis on Mitochondrial Cytochrome Oxidase Subunit I (COI) Gene

    Institute of Scientific and Technical Information of China (English)

    HU Pengfei; WANG Qian; DAI Wei; WANG Xiaomei

    2008-01-01

    The genetic differences of 15 mitten crab populations from 6 river systems in mainland China and 1 population from Russia were studied based on RFLP analysis of mitochondrial cytochrome oxidase subunit I (COI).The results showed that Tas I-RFLP pattern could be used as a genetic marker to distinguish Eriocheir hepuensis from Eriocheir sinensis, Eriocheirjaponica and Eriocheir leptognathus;genetic distances among 13 populations ofEriocheir sinensis range from 0 to 0.015, indicating that they were different geographic strains;the subspecies status ofEriocheir sinensis and Eriocheir hepuensis (population from Nanliujiang) were considered owning to their genetic distances of 0.02-0.044,indicating that genetic divergence between them was low; Eriocheir leptognathus (population from Nanpaihe, Tianjin) was the most distant taxon with genetic distances value of 0.147-0.195,which could be defined as genetic distances between species in genus Eriocheir.

  5. Conservation genetics of managed ungulate populations

    Science.gov (United States)

    Scribner, Kim T.

    1993-01-01

    Natural populations of many species are increasingly impacted by human activities. Perturbations are particularly pronunced for large ungulates due in part to sport and commercial harvest, to reductions and fragmentation of native habitat, and as the result of reintroductions. These perturbations affect population size, sex and age composition, and population breeding structure, and as a consequence affect the levels and partitioning of genetic variation. Three case histories highlighting long-term ecological genetic research on mule deer Odocoileus hemionus (Rafinesque, 1817), white-tailed deer O. virginianus (Zimmermann, 1780), and Alpine ibex Capra i. ibex Linnaeus, 1758 are presented. Joint examinations of population ecological and genetic data from several populations of each species reveal: (1) that populations are not in genetic equilibrium, but that allele frequencies and heterozygosity change dramatically over time and among cohorts produced in successive years, (2) populations are genetically structured over short and large geographic distances reflecting local breeding structure and patterns of gene flow, respectively; however, this structure is quite dynamic over time, due in part to population exploitation, and (3) restocking programs are often undertaken with small numbers of founding individuals resulting in dramatic declines in levels of genetic variability and increasing levels of genetic differentiation among populations due to genetic drift. Genetic characteristics have and will continue to provide valuable indirect sources of information relating enviromental and human perturbations to changes in population processes.

  6. Challenges in the Provision of Library Services for Distance ...

    African Journals Online (AJOL)

    Challenges in the Provision of Library Services for Distance Education: A Case Study of ... focus has turned to the role of libraries in the distance learning process. ... and those who design and implement such distance education programmes.

  7. Genetic Testing for ALS

    Science.gov (United States)

    ... Involved Donate Familial Amyotrophic Lateral Sclerosis (FALS) and Genetic Testing By Deborah Hartzfeld, MS, CGC, Certified Genetic Counselor ... in your area, please visit www.nsgc.org . Genetic Testing Genetic testing can help determine the cause of ...

  8. Genetic Science Learning Center

    Science.gov (United States)

    ... Mouse Party on Learn.Genetics.utah.edu Students doing the Tree of Genetic Traits activity Learn.Genetics is one of the most widely used science education websites in the world The Community Genetics ...

  9. Deciphering the Distance between Distance Education and Working Professionals in Difficult Geographies

    Science.gov (United States)

    Pandey, Jatin; Singh, Manjari

    2015-01-01

    This study investigates the factors that draw working professionals towards distance education programs, and the factors that sustain their distance education experience. The study is conducted in difficult terrains of Uttarakhand, a hilly state in India which helps us investigate the phenomenon in difficult geographies. Through interviews of ten…

  10. Fast Exact Euclidean Distance (FEED) : A new class of adaptable distance transforms

    NARCIS (Netherlands)

    Schouten, Theo E.; van den Broek, Egon L.

    2014-01-01

    A new unique class of foldable distance transforms of digital images (DT) is introduced, baptized: Fast Exact Euclidean Distance (FEED) transforms. FEED class algorithms calculate the DT startingdirectly from the definition or rather its inverse. The principle of FEED class algorithms is introduced,

  11. Fast Exact Euclidean Distance (FEED): A new class of adaptable distance transforms

    NARCIS (Netherlands)

    Schouten, Theo E.; Broek, van den Egon L.

    2014-01-01

    A new unique class of foldable distance transforms of digital images (DT) is introduced, baptized: Fast Exact Euclidean Distance (FEED) transforms. FEED class algorithms calculate the DT starting directly from the definition or rather its inverse. The principle of FEED class algorithms is introduced

  12. Fast Exact Euclidean Distance (FEED): A new class of adaptable distance transforms

    NARCIS (Netherlands)

    Schouten, Theo E.; van den Broek, Egon

    2014-01-01

    A new unique class of foldable distance transforms of digital images (DT) is introduced, baptized: Fast Exact Euclidean Distance (FEED) transforms. FEED class algorithms calculate the DT starting directly from the definition or rather its inverse. The principle of FEED class algorithms is

  13. Making Distance Visible: Assembling Nearness in an Online Distance Learning Programme

    Science.gov (United States)

    Ross, Jen; Gallagher, Michael Sean; Macleod, Hamish

    2013-01-01

    Online distance learners are in a particularly complex relationship with the educational institutions they belong to (Bayne, Gallagher, & Lamb, 2012). For part-time distance students, arrivals and departures can be multiple and invisible as students take courses, take breaks, move into independent study phases of a programme, find work or…

  14. The Lesotho Distance Teaching Centre: Five Years' Learning. IEC Broadsheets on Distance Learning No. 16.

    Science.gov (United States)

    Murphy, Paud

    This report describes the activities of the first 5 years of the Lesotho Distance Teaching Center, which uses distance teaching methods to bring education to more people in Lesotho. Also described are the Center's internal organization, its relationship to other organizations in Lesotho, its costs, and some evaluation findings. Background…

  15. The Lesotho Distance Teaching Centre: Five Years' Learning. IEC Broadsheets on Distance Learning No. 16.

    Science.gov (United States)

    Murphy, Paud

    This report describes the activities of the first 5 years of the Lesotho Distance Teaching Center, which uses distance teaching methods to bring education to more people in Lesotho. Also described are the Center's internal organization, its relationship to other organizations in Lesotho, its costs, and some evaluation findings. Background…

  16. Cultural Differences in Transactional Distance Preference by Arab and American Distance Learners

    Science.gov (United States)

    Al-Harthi, Aisha S.

    2010-01-01

    This study investigated the differences between Arab and American distance learners' preference in the 2 components of transactional distance (structure and interaction) and their relation to learners' self-efficacy and help seeking. The study sample consisted of 95 cases from each group (N = 190). Study results indicated significant differences…

  17. Who Am I as a Distance Tutor? An Investigation of Distance Tutors' Professional Identity in China

    Science.gov (United States)

    Xiao, Junhong

    2016-01-01

    Much research has been conducted in the area of teacher professional identity in the past decades. Nonetheless, very little attention has been paid to the professional identity of tutors in distance education. Using interviews, this study set out to investigate distance tutors' claimed and assigned professional identities, their actual, ought and…

  18. Population genetic structure of a three-host tick, Amblyomma dissimile, in eastern Venezuela.

    Science.gov (United States)

    Lampo, M; Rangel, Y; Mata, A

    1998-12-01

    Patterns of genetic variation for the tick Amblyomma dissimile were analyzed from a total of 200 ticks collected on 12 toads (Bufo marinus), 14 snakes (Boa constrictor), and 8 lizards (Iguana iguana) at 11 localities. The analyses were performed on electrophoretic data from 8 isozyme loci. Mean heterozygosity per locus was 6% (+/-3.1) per population. Differences in allelic frequencies among ticks from different individual hosts were the major source of genetic variability in this study. Host species was a smaller source of genetic variation. Genetic distances between localities varied according to which host species was present in each locality, and these appeared to be related to the extent of habitat overlap between host species. The smallest genetic distances between samples from different host species were recorded for I. iguana and B. constrictor. In contrast, the genetic distances between tick samples from B. marinus and either of the reptile species were significantly larger than between tick samples from this amphibian species. Ecological variables or the geographic distance did not explain the local patterns of differentiation observed in A. dissimile. Major genetic differences between island and mainland sites (0.03702) suggested an association between genetic distances and geographic isolation. The consistency between patterns of genetic variation and those of host home range overlap suggests that host dispersion is the main force structuring the genetic variation within this tick species.

  19. Genetic Diversity and Spatial Genetic Structure of the Grassland Perennial Saxifraga granulata along Two River Systems.

    Directory of Open Access Journals (Sweden)

    Sascha van der Meer

    Full Text Available Due to changes in land use, the natural habitats of an increasing number of plant species have become more and more fragmented. In landscapes that consist of patches of suitable habitat, the frequency and extent of long-distance seed dispersal can be expected to be an important factor determining local genetic diversity and regional population structure of the remaining populations. In plant species that are restricted to riparian habitats, rivers can be expected to have a strong impact on the dynamics and spatial genetic structure of populations as they may enable long-distance seed dispersal and thus maintain gene flow between fragmented populations. In this study, we used polymorphic microsatellite markers to investigate the genetic diversity and the spatial genetic structure of 28 populations of Saxifraga granulata along two rivers in central Belgium. We hypothesized that rivers might be essential for gene flow among increasingly isolated populations of this species. Genetic diversity was high (HS = 0.68, which to a certain extent can be explained by the octoploid nature of S. granulata in the study area. Populations along the Dijle and Demer rivers were also highly differentiated (G"ST = 0.269 and 0.164 and DEST = 0.190 and 0.124, respectively and showed significant isolation-by-distance, indicating moderate levels of gene flow primarily between populations that are geographically close to each other. Along the river Demer population genetic diversity was higher upstream than downstream, suggesting that seed dispersal via the water was not the primary mode of dispersal. Overall, these results indicate that despite increasing fragmentation populations along both rivers were highly genetically diverse. The high ploidy level and longevity of S. granulata have most likely buffered negative effects of fragmentation on genetic diversity and the spatial genetic structure of populations in riparian grasslands.

  20. Genetic Diversity and Spatial Genetic Structure of the Grassland Perennial Saxifraga granulata along Two River Systems.

    Science.gov (United States)

    van der Meer, Sascha; Jacquemyn, Hans

    2015-01-01

    Due to changes in land use, the natural habitats of an increasing number of plant species have become more and more fragmented. In landscapes that consist of patches of suitable habitat, the frequency and extent of long-distance seed dispersal can be expected to be an important factor determining local genetic diversity and regional population structure of the remaining populations. In plant species that are restricted to riparian habitats, rivers can be expected to have a strong impact on the dynamics and spatial genetic structure of populations as they may enable long-distance seed dispersal and thus maintain gene flow between fragmented populations. In this study, we used polymorphic microsatellite markers to investigate the genetic diversity and the spatial genetic structure of 28 populations of Saxifraga granulata along two rivers in central Belgium. We hypothesized that rivers might be essential for gene flow among increasingly isolated populations of this species. Genetic diversity was high (HS = 0.68), which to a certain extent can be explained by the octoploid nature of S. granulata in the study area. Populations along the Dijle and Demer rivers were also highly differentiated (G"ST = 0.269 and 0.164 and DEST = 0.190 and 0.124, respectively) and showed significant isolation-by-distance, indicating moderate levels of gene flow primarily between populations that are geographically close to each other. Along the river Demer population genetic diversity was higher upstream than downstream, suggesting that seed dispersal via the water was not the primary mode of dispersal. Overall, these results indicate that despite increasing fragmentation populations along both rivers were highly genetically diverse. The high ploidy level and longevity of S. granulata have most likely buffered negative effects of fragmentation on genetic diversity and the spatial genetic structure of populations in riparian grasslands.