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Sample records for generally showed smaller

  1. Size Matters a Lot: Drought-Affected Italian Oaks Are Smaller and Show Lower Growth Prior to Tree Death

    Science.gov (United States)

    Colangelo, Michele; Camarero, Jesús J.; Borghetti, Marco; Gazol, Antonio; Gentilesca, Tiziana; Ripullone, Francesco

    2017-01-01

    Hydraulic theory suggests that tall trees are at greater risk of drought-triggered death caused by hydraulic failure than small trees. In addition the drop in growth, observed in several tree species prior to death, is often interpreted as an early-warning signal of impending death. We test these hypotheses by comparing size, growth, and wood-anatomy patterns of living and now-dead trees in two Italian oak forests showing recent mortality episodes. The mortality probability of trees is modeled as a function of recent growth and tree size. Drift-diffusion-jump (DDJ) metrics are used to detect early-warning signals. We found that the tallest trees of the anisohydric Italian oak better survived drought contrary to what was predicted by the theory. Dead trees were characterized by a lower height and radial-growth trend than living trees in both study sites. The growth reduction of now-dead trees started about 10 years prior to their death and after two severe spring droughts during the early 2000s. This critical transition in growth was detected by DDJ metrics in the most affected site. Dead trees were also more sensitive to drought stress in this site indicating different susceptibility to water shortage between trees. Dead trees did not form earlywood vessels with smaller lumen diameter than surviving trees but tended to form wider latewood vessels with a higher percentage of vessel area. Since living and dead trees showed similar competition we did not expect that moderate thinning and a reduction in tree density would increase the short-term survival probability of trees. PMID:28270816

  2. Game Show Mathematics: Specializing, Conjecturing, Generalizing, and Convincing

    Science.gov (United States)

    Lane, Catherine Pullin; Harkness, Shelly Sheats

    2012-01-01

    This article describes the authors' use of three game shows--"Survivor," "The Biggest Loser," and "Deal or No Deal?"--to determine to what degree students engaged in mathematical thinking: specializing, conjecturing, generalizing, and convincing (Burton, 1984). Student responses to the task of creating winning strategies to these shows were…

  3. Neutrino Radiation Showing a Christodoulou Memory Effect in General Relativity

    CERN Document Server

    Bieri, Lydia

    2013-01-01

    We describe neutrino radiation in general relativity by introducing the energy-momentum tensor of a null fluid into the Einstein equations. Investigating the geometry and analysis at null infinity, we prove that a component of the null fluid enlarges the Christodoulou memory effect of gravitational waves. The description of neutrinos in general relativity as a null fluid can be regarded as a limiting case of a more general description using the massless limit of the Einstein-Vlasov system. The present authors with co-authors have work in progress to generalize the results of this paper using this more general description. Gigantic neutrino bursts occur in our universe in core-collapse supernovae and in the mergers of neutron star binaries.

  4. Towards smaller gap microbulks

    CERN Document Server

    Attié, D.; Dafni, T; Ferrer-Ribas, E.; Ferrer-Ribas, E; Ferry, S; Giomataris, Y; Herrera, D C; Iguaz, F J; Irastorza, I G; Kebbiri, M; Papaevangelou, T; de Oliveira, R; Seguí, L; Tomás, A

    2014-01-01

    Small gap Micromegas detectors ( < 50 μm) are expected to be optimal for high pressure applications. Combining the microbulk manufacturing technique with a small gap can result in attractive detectors for rare event detection, in particular double beta decay or dark matter searches. We present novel results obtained with small gap microbulks (25 and 12.5 μm) that have been manufactured recently. For the first time for this type of detectors, we show experimentally that for each amplification gap there is an optimal pressure and that smaller gaps are more suitable for higher pressures.

  5. Weather Station and Sensor Locations, Kansas Weather Stations, Published in 2005, Smaller than 1:100000 scale, Kansas Adjutant General's Department.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Weather Station and Sensor Locations dataset, published at Smaller than 1:100000 scale, was produced all or in part from Published Reports/Deeds information as...

  6. Time to tackle the incumbency advantage in science: A survey of scientists shows strong support for funding policies that would distribute funds more evenly among laboratories and thereby benefit new and smaller research groups

    OpenAIRE

    Ballabeni, Andrea; Hemenway, David; Scita, Giorgio

    2016-01-01

    The fact that larger, well‐established labs have more success securing research grants creates an unfair situation for younger researchers. A survey shows that many scientists favour alternative funding schemes that would distribute grant money more equally or based on the merit of the individual.

  7. Chernobyl birds have smaller brains.

    Science.gov (United States)

    Møller, Anders Pape; Bonisoli-Alquati, Andea; Rudolfsen, Geir; Mousseau, Timothy A

    2011-02-04

    Animals living in areas contaminated by radioactive material from Chernobyl suffer from increased oxidative stress and low levels of antioxidants. Therefore, normal development of the nervous system is jeopardized as reflected by high frequencies of developmental errors, reduced brain size and impaired cognitive abilities in humans. Alternatively, associations between psychological effects and radiation have been attributed to post-traumatic stress in humans. Here we used an extensive sample of 550 birds belonging to 48 species to test the prediction that even in the absence of post-traumatic stress, there is a negative association between relative brain size and level of background radiation. We found a negative association between brain size as reflected by external head volume and level of background radiation, independent of structural body size and body mass. The observed reduction in brain size in relation to background radiation amounted to 5% across the range of almost a factor 5,000 in radiation level. Species differed significantly in reduction in brain size with increasing background radiation, and brain size was the only morphological character that showed a negative relationship with radiation. Brain size was significantly smaller in yearlings than in older individuals. Low dose radiation can have significant effects on normal brain development as reflected by brain size and therefore potentially cognitive ability. The fact that brain size was smaller in yearlings than in older individuals implies that there was significant directional selection on brain size with individuals with larger brains experiencing a viability advantage.

  8. Storm Sewage Dilution in Smaller Streams

    DEFF Research Database (Denmark)

    Larsen, Torben; Vestergaard, Kristian

    1987-01-01

    A numerical model has been used to show how dilution in smaller streams can be effected by unsteady hydraulic conditions caused by a storm sewage overflow.......A numerical model has been used to show how dilution in smaller streams can be effected by unsteady hydraulic conditions caused by a storm sewage overflow....

  9. Chernobyl birds have smaller brains.

    Directory of Open Access Journals (Sweden)

    Anders Pape Møller

    Full Text Available BACKGROUND: Animals living in areas contaminated by radioactive material from Chernobyl suffer from increased oxidative stress and low levels of antioxidants. Therefore, normal development of the nervous system is jeopardized as reflected by high frequencies of developmental errors, reduced brain size and impaired cognitive abilities in humans. Alternatively, associations between psychological effects and radiation have been attributed to post-traumatic stress in humans. METHODOLOGY/PRINCIPAL FINDING: Here we used an extensive sample of 550 birds belonging to 48 species to test the prediction that even in the absence of post-traumatic stress, there is a negative association between relative brain size and level of background radiation. We found a negative association between brain size as reflected by external head volume and level of background radiation, independent of structural body size and body mass. The observed reduction in brain size in relation to background radiation amounted to 5% across the range of almost a factor 5,000 in radiation level. Species differed significantly in reduction in brain size with increasing background radiation, and brain size was the only morphological character that showed a negative relationship with radiation. Brain size was significantly smaller in yearlings than in older individuals. CONCLUSIONS/SIGNIFICANCE: Low dose radiation can have significant effects on normal brain development as reflected by brain size and therefore potentially cognitive ability. The fact that brain size was smaller in yearlings than in older individuals implies that there was significant directional selection on brain size with individuals with larger brains experiencing a viability advantage.

  10. Wellness strategies for smaller businesses.

    Science.gov (United States)

    Neely, Marc

    2012-01-01

    While innovative smaller companies are implementing employee wellness programs, many smaller firms may point to a lack of resources, such as staffing and financial resources, to establish and sustain a wellness program. The uncertain economy and rising health care costs have caused many smaller businesses to focus on core business strategies to keep the doors open and the business going. However, innovative companies realize that building a culture of health is a long-term business strategy directly related to improving the bottom line. This article highlights one company's approach to wellness and the results of the company's programs. It also outlines the components of a successful wellness program and suggests practical implementation steps for smaller businesses.

  11. Anhedonia and general distress show dissociable ventromedial prefrontal cortex connectivity in major depressive disorder.

    Science.gov (United States)

    Young, C B; Chen, T; Nusslock, R; Keller, J; Schatzberg, A F; Menon, V

    2016-05-17

    Anhedonia, the reduced ability to experience pleasure in response to otherwise rewarding stimuli, is a core symptom of major depressive disorder (MDD). Although the posterior ventromedial prefrontal cortex (pVMPFC) and its functional connections have been consistently implicated in MDD, their roles in anhedonia remain poorly understood. Furthermore, it is unknown whether anhedonia is primarily associated with intrinsic 'resting-state' pVMPFC functional connectivity or an inability to modulate connectivity in a context-specific manner. To address these gaps, a pVMPFC region of interest was first identified using activation likelihood estimation meta-analysis. pVMPFC connectivity was then examined in relation to anhedonia and general distress symptoms of depression, using both resting-state and task-based functional magnetic resonance imaging involving pleasant music, in current MDD and healthy control groups. In MDD, pVMPFC connectivity was negatively correlated with anhedonia but not general distress during music listening in key reward- and emotion-processing regions, including nucleus accumbens, ventral tegmental area/substantia nigra, orbitofrontal cortex and insula, as well as fronto-temporal regions involved in tracking complex sound sequences, including middle temporal gyrus and inferior frontal gyrus. No such dissociations were observed in the healthy controls, and resting-state pVMPFC connectivity did not dissociate anhedonia from general distress in either group. Our findings demonstrate that anhedonia in MDD is associated with context-specific deficits in pVMPFC connectivity with the mesolimbic reward system when encountering pleasurable stimuli, rather than a static deficit in intrinsic resting-state connectivity. Critically, identification of functional circuits associated with anhedonia better characterizes MDD heterogeneity and may help track of one of its core symptoms.

  12. Smaller plates, less food waste

    DEFF Research Database (Denmark)

    Hansen, Pelle Guldborg; Schmidt, Karsten; Skov, Laurits Rhoden

    With roughly one-third of food produced for human consumption lost or wasted globally (about 1.3 billion tons per year), the impact on the environment cannot be anymore neglected. Actions at all points in the production chain are now urgent, including reductions in food waste at home, by retailer...... the hypothesis that dishware size plays an important role in the amount of food wasted among Danish adults in a self-service eating setting. This finding has PHN implications: slight changes in the foodscape can contribute to sustainable food consumption goals....... was to investigate whether the size of the dishware would non-reflectively influence the amount of foods taken from an “ad-libitum” buffet and the resulting amount of waste. Sample consisted of Danish business leaders that took part in a congress in Copenhagen, Denmark. Two buffet tables were set up on two separate....... All food waste was collected in designated trash bags (different colour in each floor) and weighted in bulk by students. Smaller plates appear to have decreased food waste by 26% compared to the standard sized plates at a single serving in a self-service eating setting. This pilot study supports...

  13. Smaller Fleas: Viruses of Microorganisms

    OpenAIRE

    Paul Hyman; Stephen T. Abedon

    2012-01-01

    Life forms can be roughly differentiated into those that are microscopic versus those that are not as well as those that are multicellular and those that, instead, are unicellular. Cellular organisms seem generally able to host viruses, and this propensity carries over to those that are both microscopic and less than truly multicellular. These viruses of microorganisms, or VoMs, in fact exist as the world’s most abundant somewhat autonomous genetic entities and include the viruses of domain B...

  14. Mammals evolve faster on smaller islands.

    Science.gov (United States)

    Millien, Virginie

    2011-07-01

    Island mammals often display remarkable evolutionary changes in size and morphology. Both theory and empirical data support the hypothesis that island mammals evolve at faster rates than their mainland congeners. It is also often assumed that the island effect is stronger and that evolution is faster on the smallest islands. I used a dataset assembled from the literature to test these assumptions for the first time. I show that mammals on smaller islands do indeed evolve more rapidly than mammals on larger islands, and also evolve by a greater amount. These results fit well the theory of an evolutionary burst due to the opening of new ecological opportunities on islands. This evolutionary burst is expected to be the strongest on the smallest islands where the contrast between the island and the mainland environments is the most dramatic.

  15. Drug reaction with eosinophilia and systemic symptoms syndrome is not uncommon and shows better clinical outcome than generally recognised.

    Science.gov (United States)

    Nam, Y H; Park, M R; Nam, H J; Lee, S K; Kim, K H; Roh, M S; Um, S-J; Son, C-H

    2015-01-01

    Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare disease which can cause severe morbidity and mortality. The aim of this study is to evaluate the clinical manifestation and course of DRESS syndrome. We conducted a retrospective analysis of prospectively collected data in 45 patients with DRESS syndrome diagnosed between September 2009 and August 2011. The most common causative drug group was antibiotics (n=13, 28.9%), followed by anticonvulsants (n=12, 26.7%), antituberculosis drugs (n=6, 13.3%), non-steroidal anti-inflammatory drugs (n=4, 8.9%), undetermined agents (n=4, 8.9%), allopurinol (n=3, 6.7%), and others (n=3, 6.7%). The latency period ranged from 2 to 120 days, with a mean of 20.2 ± 24.3 days. The longest latency period was noted for the antituberculosis drug group, at 46.5 ± 29.9 days. Eosinophilia in peripheral blood examination was noted in 35 subjects (77.8%). Atypical lymphocytosis was noted in 16 patients (35.6%), and thrombocytopenia in seven patients (15.6%). Hepatic involvement was noted in 39 (86.7%) study patients, kidney in eight (17.8%), lung in four (8.9%), and central nervous system in one (2.3%). Systemic corticosteroids were administered to 10 patients (22.2%). Forty-three patients (95.6%) showed complete recovery, while two patients had poor outcomes. DRESS syndrome was not more uncommon than generally recognised. Antibiotics were the most frequently implicated drug group, followed by anticonvulsants. Most patients with this disease showed a better clinical outcome than that which had been generally expected. Copyright © 2013 SEICAP. Published by Elsevier Espana. All rights reserved.

  16. Strategies for selling smaller pools of loans

    OpenAIRE

    McCarthy, John

    2006-01-01

    Proceedings of the Conference on the Secondary Market for Community Development Loans In September 2006, the Federal Reserve hosted a conference on secondary markets for community development loans. A theme that emerged was that techniques, programs, and structures that work for large loans do not necessarily work for small ones. In this article, I briefly outline why smaller deals can be more difficult to finance, and describe two ways in which the Community Preservation Corporation (CPC) ha...

  17. Selective Loss of Smaller Spines in Schizophrenia.

    Science.gov (United States)

    MacDonald, Matthew L; Alhassan, Jamil; Newman, Jason T; Richard, Michelle; Gu, Hong; Kelly, Ryan M; Sampson, Alan R; Fish, Kenneth N; Penzes, Peter; Wills, Zachary P; Lewis, David A; Sweet, Robert A

    2017-06-01

    Decreased density of dendritic spines in adult schizophrenia subjects has been hypothesized to result from increased pruning of excess synapses in adolescence. In vivo imaging studies have confirmed that synaptic pruning is largely driven by the loss of large or mature synapses. Thus, increased pruning throughout adolescence would likely result in a deficit of large spines in adulthood. Here, the authors examined the density and volume of dendritic spines in deep layer 3 of the auditory cortex of 20 schizophrenia and 20 matched comparison subjects as well as aberrant voltage-gated calcium channel subunit protein expression linked to spine loss. Primary auditory cortex deep layer 3 spine density and volume was assessed in 20 pairs of schizophrenia and matched comparison subjects in an initial and replication cohort (12 and eight pairs) by immunohistochemistry-confocal microscopy. Targeted mass spectrometry was used to quantify postsynaptic density and voltage-gated calcium channel protein expression. The effect of increased voltage-gated calcium channel subunit protein expression on spine density and volume was assessed in primary rat neuronal culture. Only the smallest spines are lost in deep layer 3 of the primary auditory cortex in subjects with schizophrenia, while larger spines are retained. Levels of the tryptic peptide ALFDFLK, found in the schizophrenia risk gene CACNB4, are inversely correlated with the density of smaller, but not larger, spines in schizophrenia subjects. Consistent with this observation, CACNB4 overexpression resulted in a lower density of smaller spines in primary neuronal cultures. These findings require a rethinking of the overpruning hypothesis, demonstrate a link between small spine loss and a schizophrenia risk gene, and should spur more in-depth investigations of the mechanisms that govern new or small spine generation and stabilization under normal conditions as well as how this process is impaired in schizophrenia.

  18. A high aggression strategy for smaller males.

    Directory of Open Access Journals (Sweden)

    P Andreas Svensson

    Full Text Available Male-male conflict is common among animals, but questions remain as to when, how and by whom aggression should be initiated. Factors that affect agonistic strategies include residency, the value of the contested resource and the fighting ability of the two contestants. We quantified initiation of aggression in a fish, the desert goby, Chlamydogobius eremius, by exposing nest-holding males to a male intruder. The perceived value of the resource (the nest was manipulated by exposing half of the residents to sexually receptive females for two days before the trial. Resident male aggression, however, was unaffected by perceived mating opportunities. It was also unaffected by the absolute and relative size of the intruder. Instead resident aggression was negatively related to resident male size. In particular, smaller residents attacked sooner and with greater intensity compared to larger residents. These results suggest that resident desert goby males used set, rather than conditional, strategies for initiating aggression. If intruders are more likely to flee than retaliate, small males may benefit from attacking intruders before these have had an opportunity to assess the resident and/or the resource.

  19. Hearing Impairment Is Associated with Smaller Brain Volume in Aging

    Science.gov (United States)

    Rigters, Stephanie C.; Bos, Daniel; Metselaar, Mick; Roshchupkin, Gennady V.; Baatenburg de Jong, Robert J.; Ikram, M. Arfan; Vernooij, Meike W.; Goedegebure, André

    2017-01-01

    Although recent studies show that age-related hearing impairment is associated with cerebral changes, data from a population perspective are still lacking. Therefore, we studied the relation between hearing impairment and brain volume in a large elderly cohort. From the population-based Rotterdam Study, 2,908 participants (mean age 65 years, 56% female) underwent a pure-tone audiogram to quantify hearing impairment. By performing MR imaging of the brain we quantified global and regional brain tissue volumes (total brain volume, gray matter volume, white matter (WM) volume, and lobe-specific volumes). We used multiple linear regression models, adjusting for age, sex, head size, time between hearing test and MR imaging, and relevant cognitive and cardiovascular covariates. Furthermore, we performed voxel-based morphometry to explore sub-regional differences. We found that a higher pure-tone threshold was associated with a smaller total brain volume [difference in standardized brain volume per decibel increase in hearing threshold in the age-sex adjusted model: -0.003 (95% confidence interval -0.004; -0.001)]. Specifically, WM volume was associated. Both associations were more pronounced in the lower frequencies. All associations were consistently present in all brain lobes in the lower frequencies and in most lobes in the higher frequencies, and were independent of cognitive function and cardiovascular risk factors. In voxel-based analyses we found associations of hearing impairment with smaller white volumes and some smaller and larger gray volumes, yet these were statistically non-significant. Our findings demonstrate that hearing impairment in elderly is related to smaller total brain volume, independent of cognition and cardiovascular risk factors. This mainly seems to be driven by smaller WM volume, throughout the brain.

  20. Individual Differences in the Speed of Facial Emotion Recognition Show Little Specificity but Are Strongly Related with General Mental Speed: Psychometric, Neural and Genetic Evidence.

    Science.gov (United States)

    Liu, Xinyang; Hildebrandt, Andrea; Recio, Guillermo; Sommer, Werner; Cai, Xinxia; Wilhelm, Oliver

    2017-01-01

    Facial identity and facial expression processing are crucial socio-emotional abilities but seem to show only limited psychometric uniqueness when the processing speed is considered in easy tasks. We applied a comprehensive measurement of processing speed and contrasted performance specificity in socio-emotional, social and non-social stimuli from an individual differences perspective. Performance in a multivariate task battery could be best modeled by a general speed factor and a first-order factor capturing some specific variance due to processing emotional facial expressions. We further tested equivalence of the relationships between speed factors and polymorphisms of dopamine and serotonin transporter genes. Results show that the speed factors are not only psychometrically equivalent but invariant in their relation with the Catechol-O-Methyl-Transferase (COMT) Val158Met polymorphism. However, the 5-HTTLPR/rs25531 serotonin polymorphism was related with the first-order factor of emotion perception speed, suggesting a specific genetic correlate of processing emotions. We further investigated the relationship between several components of event-related brain potentials with psychometric abilities, and tested emotion specific individual differences at the neurophysiological level. Results revealed swifter emotion perception abilities to go along with larger amplitudes of the P100 and the Early Posterior Negativity (EPN), when emotion processing was modeled on its own. However, after partialling out the shared variance of emotion perception speed with general processing speed-related abilities, brain-behavior relationships did not remain specific for emotion. Together, the present results suggest that speed abilities are strongly interrelated but show some specificity for emotion processing speed at the psychometric level. At both genetic and neurophysiological levels, emotion specificity depended on whether general cognition is taken into account or not. These

  1. Individual Differences in the Speed of Facial Emotion Recognition Show Little Specificity but Are Strongly Related with General Mental Speed: Psychometric, Neural and Genetic Evidence

    Directory of Open Access Journals (Sweden)

    Xinyang Liu

    2017-08-01

    Full Text Available Facial identity and facial expression processing are crucial socio-emotional abilities but seem to show only limited psychometric uniqueness when the processing speed is considered in easy tasks. We applied a comprehensive measurement of processing speed and contrasted performance specificity in socio-emotional, social and non-social stimuli from an individual differences perspective. Performance in a multivariate task battery could be best modeled by a general speed factor and a first-order factor capturing some specific variance due to processing emotional facial expressions. We further tested equivalence of the relationships between speed factors and polymorphisms of dopamine and serotonin transporter genes. Results show that the speed factors are not only psychometrically equivalent but invariant in their relation with the Catechol-O-Methyl-Transferase (COMT Val158Met polymorphism. However, the 5-HTTLPR/rs25531 serotonin polymorphism was related with the first-order factor of emotion perception speed, suggesting a specific genetic correlate of processing emotions. We further investigated the relationship between several components of event-related brain potentials with psychometric abilities, and tested emotion specific individual differences at the neurophysiological level. Results revealed swifter emotion perception abilities to go along with larger amplitudes of the P100 and the Early Posterior Negativity (EPN, when emotion processing was modeled on its own. However, after partialling out the shared variance of emotion perception speed with general processing speed-related abilities, brain-behavior relationships did not remain specific for emotion. Together, the present results suggest that speed abilities are strongly interrelated but show some specificity for emotion processing speed at the psychometric level. At both genetic and neurophysiological levels, emotion specificity depended on whether general cognition is taken into account

  2. Individual Differences in the Speed of Facial Emotion Recognition Show Little Specificity but Are Strongly Related with General Mental Speed: Psychometric, Neural and Genetic Evidence

    Science.gov (United States)

    Liu, Xinyang; Hildebrandt, Andrea; Recio, Guillermo; Sommer, Werner; Cai, Xinxia; Wilhelm, Oliver

    2017-01-01

    Facial identity and facial expression processing are crucial socio-emotional abilities but seem to show only limited psychometric uniqueness when the processing speed is considered in easy tasks. We applied a comprehensive measurement of processing speed and contrasted performance specificity in socio-emotional, social and non-social stimuli from an individual differences perspective. Performance in a multivariate task battery could be best modeled by a general speed factor and a first-order factor capturing some specific variance due to processing emotional facial expressions. We further tested equivalence of the relationships between speed factors and polymorphisms of dopamine and serotonin transporter genes. Results show that the speed factors are not only psychometrically equivalent but invariant in their relation with the Catechol-O-Methyl-Transferase (COMT) Val158Met polymorphism. However, the 5-HTTLPR/rs25531 serotonin polymorphism was related with the first-order factor of emotion perception speed, suggesting a specific genetic correlate of processing emotions. We further investigated the relationship between several components of event-related brain potentials with psychometric abilities, and tested emotion specific individual differences at the neurophysiological level. Results revealed swifter emotion perception abilities to go along with larger amplitudes of the P100 and the Early Posterior Negativity (EPN), when emotion processing was modeled on its own. However, after partialling out the shared variance of emotion perception speed with general processing speed-related abilities, brain-behavior relationships did not remain specific for emotion. Together, the present results suggest that speed abilities are strongly interrelated but show some specificity for emotion processing speed at the psychometric level. At both genetic and neurophysiological levels, emotion specificity depended on whether general cognition is taken into account or not. These

  3. Automated measurement of hippocampal subfields in PTSD: Evidence for smaller dentate gyrus volume.

    Science.gov (United States)

    Hayes, Jasmeet P; Hayes, Scott; Miller, Danielle R; Lafleche, Ginette; Logue, Mark W; Verfaellie, Mieke

    2017-09-09

    Smaller hippocampal volume has been consistently observed as a biomarker of posttraumatic stress disorder (PTSD). However, less is known about individual volumes of the subfields composing the hippocampus such as the dentate gyrus and cornu ammonis (CA) fields 1-4 in PTSD. The aim of the present study was to examine the hypothesis that volume of the dentate gyrus, a region putatively involved in distinctive encoding of similar events, is smaller in individuals with PTSD versus trauma-exposed controls. Ninety-seven recent war veterans underwent structural imaging on a 3T scanner and were assessed for PTSD using the Clinician-Administered PTSD Scale. The hippocampal subfield automated segmentation program available through FreeSurfer was used to segment the CA4/dentate gyrus, CA1, CA2/3, presubiculum, and subiculum of the hippocampus. Results showed that CA4/dentate gyrus subfield volume was significantly smaller in veterans with PTSD and scaled inversely with PTSD symptom severity. These results support the view that dentate gyrus abnormalities are associated with symptoms of PTSD, although additional evidence is necessary to determine whether these abnormalities underlie fear generalization and other memory alterations in PTSD. Published by Elsevier Ltd.

  4. A Japanese child with asymptomatic elevation of serum creatine kinase shows PTRF-CAVIN mutation matching with congenital generalized lipodystrophy type 4.

    Science.gov (United States)

    Dwianingsih, Ery Kus; Takeshima, Yasuhiro; Itoh, Kyoko; Yamauchi, Yumiko; Awano, Hiroyuki; Malueka, Rusdy Ghazali; Nishida, Atsushi; Ota, Mitsunori; Yagi, Mariko; Matsuo, Masafumi

    2010-01-01

    Congenital generalized lipodystrophy (CGL), characterized by generalized absence of adipose tissue, has heterogeneous causes. Recently, a novel type of CGL complicated by muscular dystrophy was categorized as CGL4 caused by PTRF-CAVIN deficiency. However, it is unknown whether CGL4 exhibits clinical abnormalities during the infantile period. Here, we describe the youngest Japanese case of CGL4-a Japanese girl with asymptomatic high serum creatine kinase (CK) levels at 3months old. She was referred to our hospital at 5months of age because of her elevated serum CK (2528IU/L). Generalized absence of adipose tissue was first recognized at 2years of age. Mutation analysis of genes known to be responsible for CGL1-3 failed to disclose any abnormalities. Instead, analysis of the PTRF-CAVIN gene encoding PTRF-CAVIN revealed compound heterozygous mutations, one allele contained an insertion (c.696_697insC) and the other allele harbored a novel nonsense mutation (c.512C>A). Our patient had low serum leptin and adiponectin levels and insulin resistance. Pathological studies on biopsied muscle disclosed mild dystrophic change and highly reduced expression of PTRF-CAVIN. It was concluded that our PTRF-CAVIN deficient patient showed not only CGL but also asymptomatic elevation of serum CK because of her mild muscle dystrophic change. Copyright © 2010 Elsevier Inc. All rights reserved.

  5. Development of a contour map showing generalized skew coefficients of annual peak discharges of rural, unregulated streams in New York, excluding Long Island

    Science.gov (United States)

    Lumia, Richard; Baevsky, Yvonne H.

    2000-01-01

    Flood-frequency relations that are developed by fitting the logarithms of annual peak discharges to a Pearson Type-III distribution are sensitive to skew coefficients. Estimates of population skew for a site are improved when computed from the weighted average of (1) the sample (station) skew, and (2) an unbiased, generalized skew estimate. A weighting technique based on the number of years of record at each of 226 sites was used to develop a contour map of unbiased, generalized skew coefficients for New York. An attempt was made to group (regionalize) the station skew coefficients into five hydrologically similar areas of New York, but the statewide version proved to be as accurate as the regionalized version and therefore was adopted as the final generalized skew-coefficient map for New York. An error analysis showed the statewide contour map to have lower MSE?s (mean square errors) than those computed from (1) the five regional skewcoefficient contour maps, (2) a previously used (1982) nationwide skew coefficient map, and (3) the weighted mean of skew coefficients for sites within each of five hydrologically uniform, but distinct areas of New York.

  6. The fading affect bias shows positive outcomes at the general but not the individual level of analysis in the context of social media.

    Science.gov (United States)

    Gibbons, Jeffrey A; Horowitz, Kyle A; Dunlap, Spencer M

    2017-08-01

    Unpleasant affect fades faster than pleasant affect (e.g., Walker, Vogl, & Thompson, 1997); this effect is referred to as the Fading Affect Bias (FAB; Walker, Skowronski, Gibbons, Vogl, & Thompson, 2003a). Research shows that the FAB is consistently related to positive/healthy outcomes at a general but not at a specific level of analysis based on event types and individual differences (e.g., Gibbons et al., 2013). Based on the positive outcomes for FAB and negative outcomes for social media (Bolton et al., 2013; Huang, 2010), the current study examined FAB in the context of social media events along with related individual differences. General positive outcomes were shown in the form of robust FAB effects across social media and non-social media events, a larger FAB for non-social media events than for social media events, negative correlations of FAB with depression, anxiety, and stress as well as a positive correlation of FAB with self-esteem. However, the lack of a negative correlation between FAB and anxiety for social media events in a 3-way interaction did not show positive outcomes at a specific level of analysis. Rehearsal ratings mediated the 3-way interaction. Implications are discussed. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Analysis of large new South African dataset using two host-specificity indices shows generalism in both adult and larval ticks of mammals.

    Science.gov (United States)

    Espinaze, Marcela P A; Hellard, Eléonore; Horak, Ivan G; Cumming, Graeme S

    2016-03-01

    Ticks and tick-borne pathogens can have considerable impacts on the health of livestock, wildlife and people. Knowledge of tick-host preferences is necessary for both tick and pathogen control. Ticks were historically considered as specialist parasites, but the range of sampled host species has been limited, infestation intensity has not been included in prior analyses, and phylogenetic distances between hosts have not been previously considered. We used a large dataset of 35 604 individual collections and two host-specificity indices to assess the specificity of 61 South African tick species, as well as distinctions between adult and juvenile ticks, for 95 mammalian hosts. When accounting for host phylogeny, most adult and juvenile ticks behaved as generalists, with juveniles being significantly more generalist than adults. When we included the intensity of tick infestation, ticks exhibited a wider diversity of specificity in all life stages. Our results show that ticks of mammals in South Africa tend to behave largely as generalists and that adult ticks are more host-specific. More generally, our analysis shows that the incorporation of life-stage differences, infestation intensity and phylogenetic distances between hosts, as well as the use of more than one specificity index, can all contribute to a deeper understanding of host-parasite interactions.

  8. Health promotion in smaller workplaces in the United States.

    Science.gov (United States)

    Harris, Jeffrey R; Hannon, Peggy A; Beresford, Shirley A A; Linnan, Laura A; McLellan, Deborah L

    2014-01-01

    Most American workplaces are smaller, with fewer than 1,000 employees. Many of these employees are low-wage earners and at increased risk for chronic diseases. Owing to the challenges smaller workplaces face to offering health-promotion programs, their employees often lack access to health-promotion opportunities available at larger workplaces. Many smaller employers do not offer health insurance, which is currently the major funding vehicle for health-promotion services. They also have few health-promotion vendors to serve them and low internal capacity for, and commitment to, delivery of on-site programs. The programs they offer, whether aimed at health promotion alone or integrated with health protection, are rarely comprehensive and are understudied. Research priorities for health promotion in smaller workplaces include developing programs feasible for the smallest workplaces with fewer than 20 employees. Policy priorities include incentives for smaller workplaces to implement comprehensive programs and an ongoing system for monitoring and evaluation.

  9. Show Time

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正> Story: Show Time!The whole class presents the story"Under the Sea".Everyone is so excited and happy.Both Leo and Kathy show their parentsthe characters of the play."Who’s he?"asks Kathy’s mom."He’s the prince."Kathy replies."Who’s she?"asks Leo’s dad."She’s the queen."Leo replieswith a smile.

  10. Snobbish Show

    Institute of Scientific and Technical Information of China (English)

    YIN PUMIN

    2010-01-01

    @@ The State Administration of Radio,Film and Television (SARFT),China's media watchdog,issued a new set of mles on June 9 that strictly regulate TV match-making shows,which have been sweeping the country's primetime programming. "Improper social and love values such as money worship should not be presented in these shows.Humiliation,verbal attacks and sex-implied vulgar content are not allowed" the new roles said.

  11. Clicking-Machine Operator (boot & show; leather prod.) 6-62.055--Technical Report on Standardization of the General Aptitude Test Battery.

    Science.gov (United States)

    Manpower Administration (DOL), Washington, DC. U.S. Training and Employment Service.

    The United States Training and Employment Service General Aptitude Test Battery (GATB), first published in 1947, has been included in a continuing program of research to validate the tests against success in many different occupations. The GATB consists of 12 tests which measure nine aptitudes: General Learning Ability; Verbal Aptitude; Numerical…

  12. Inspection considerations for holes 0. 040 inch and smaller

    Energy Technology Data Exchange (ETDEWEB)

    1980-03-01

    The accurate inspection of hole size and location for holes smaller than 0.040 inch necessitates several considerations beyond those normally encountered for larger holes. The technical aspects are described herein.

  13. Pheromone Chemistry of the Smaller European Elm Bark Beetle.

    Science.gov (United States)

    Beck, Keith

    1978-01-01

    Discusses the aggregation pheromone of the smaller European elm bark beetle, Scolytus multistriatus (Marsham), with emphasis on information that could be used in the classroom as a practical application of organic chemistry. (Author/GA)

  14. Defining Space Mission Architects for the Smaller Missions

    Science.gov (United States)

    Anderson, C.

    1999-01-01

    The definition of the Space Mission Architect (SMA) must be clear in both technical and human terms if we expect to train and/or to find people needed to architect the numbers of smaller missions expected in the future.

  15. Are LIGO's Black Holes Made From Smaller Black Holes?

    Science.gov (United States)

    Kohler, Susanna

    2017-05-01

    all the hierarchical mergers are so-called major mergers i.e., the smaller black hole of the pair is at least 70% of the mass of the larger one.Distribution of spins for 4th-generation mergers, with two different mass ratios (q= 0.7 and q= 1) and initial first-generation spins (non-spinning and maximally spinning). [Fishbach et al. 2017]The authors find that hierarchical major mergers result in a distribution of spins with a distinctive shape, peaking at a spin of a 0.7 with relatively low contribution from spins below a 0.5. Intriguingly, this distribution is universal if you include several generations of mergers, the resulting spin distribution converges to the same shape every time. This is true regardless of the details of the hierarchical merger scenario, like the exact black hole mass ratio (as long as only major mergers occur) or the initial spin distributions.Testing the ModelWhat does this tell us? Since the hierarchical merger model predicts a very specific distribution of spins for the black holes detected by LIGO, we can compare future LIGO detections to see if theyre consistent with this model.The authors calculate the statistics to show that after order 100 LIGO detections, we should be able to tell whether these black holes are consistent with a hierarchical merger formation model or not. With luck, this could mean that we will have solved this mystery within a few years of advanced LIGO operations!CitationMaya Fishbach et al 2017 ApJL 840 L24. doi:10.3847/2041-8213/aa7045

  16. EROBATIC SHOW

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    Visitors look at plane models of the Commercial Aircraft Corp. of China, developer of the count,s first homegrown large passenger jet C919, during the Singapore Airshow on February 16. The biennial event is the largest airshow in Asia and one of the most important aviation and defense shows worldwide. A number of Chinese companies took part in the event during which Okay Airways, the first privately owned aidine in China, signed a deal to acquire 12 Boeing 737 jets.

  17. Library Homepage Design at Smaller Bachelor of Arts Institutions

    Science.gov (United States)

    Jones, Scott L.; Leonard, Kirsten

    2011-01-01

    This study examined the homepages of the libraries of 175 smaller bachelor of arts institutions, coding for the presence of 98 design elements. By reporting and examining the frequency of these features, the authors noted what is and is not common practice at these libraries. They found that only fourteen elements were present on at least half of…

  18. Does Studying Vocabulary in Smaller Sets Increase Learning?

    Science.gov (United States)

    Nakata, Tatsuya; Webb, Stuart

    2016-01-01

    The present study examined the effects of part and whole learning on the acquisition of second language (L2, English) vocabulary. In whole learning, the materials to be learned are repeated in one large block, whereas, in part learning, the materials are divided into smaller blocks and repeated. Experiment 1 compared the effects of the following…

  19. Trends and patterns in smaller companies: The Danish perspective

    DEFF Research Database (Denmark)

    Ulhøi, John Parm; Madsen, Henning

    2000-01-01

    This paper presents the empirical findings of a recent survey of Danish managers, with a special focus on managers in smaller companies. The survey, called the 'Danish Management Barometer', is part of a joint research programme between the Aarhus School of Business and the Danish Association...

  20. The Underreported Use of Integrated Marketing Communication by Smaller Businesses.

    Science.gov (United States)

    Johnson, Ed

    This research suggests integrated marketing communication (IMC) is widely used by small business. In a survey of Midwest businesses, it was found that smaller business tend to integrate their marketing communication to the same extent as do larger businesses. Their advertising, P.R., and sales promotion are as likely to present a unified message,…

  1. Does Studying Vocabulary in Smaller Sets Increase Learning?

    Science.gov (United States)

    Nakata, Tatsuya; Webb, Stuart

    2016-01-01

    The present study examined the effects of part and whole learning on the acquisition of second language (L2, English) vocabulary. In whole learning, the materials to be learned are repeated in one large block, whereas, in part learning, the materials are divided into smaller blocks and repeated. Experiment 1 compared the effects of the following…

  2. Pride and Prejudice: The Choice for the Smaller Law School.

    Science.gov (United States)

    Veitch, Edward

    1981-01-01

    The means required to establish a small, but quality, local law school are discussed. Facts about the Faculty of Law at the University of New Brunswick and arguments in favor of the enhancement in quality of the smaller law schools are presented. (MLW)

  3. Smaller Schools: How Much More than a Fad?

    Science.gov (United States)

    Muir, Edward

    2001-01-01

    The movement back to smaller schools is not just another fad, but there are many questions about the effects of school size that need to be addressed (e.g., the effect of school size on student achievement; the importance networking between students, parents, and teachers; cost differences; and long-term social benefits for students). (SM)

  4. Honors Programs at Smaller Colleges. 3rd Edition. National Collegiate Honors Council Monograph Series

    Science.gov (United States)

    Schuman, Samuel

    2011-01-01

    This monograph focuses upon areas of special concern to those working with honors at smaller colleges and universities: mission, recruitment, facilities, administration, budget, and curriculum. In each area, the author makes some general suggestions about overall operating principles, note specific issues that can lead to difficulties, and suggest…

  5. Quality of the log-geometric distribution extrapolation for smaller undiscovered oil and gas pool size

    Science.gov (United States)

    Chenglin, L.; Charpentier, R.R.

    2010-01-01

    The U.S. Geological Survey procedure for the estimation of the general form of the parent distribution requires that the parameters of the log-geometric distribution be calculated and analyzed for the sensitivity of these parameters to different conditions. In this study, we derive the shape factor of a log-geometric distribution from the ratio of frequencies between adjacent bins. The shape factor has a log straight-line relationship with the ratio of frequencies. Additionally, the calculation equations of a ratio of the mean size to the lower size-class boundary are deduced. For a specific log-geometric distribution, we find that the ratio of the mean size to the lower size-class boundary is the same. We apply our analysis to simulations based on oil and gas pool distributions from four petroleum systems of Alberta, Canada and four generated distributions. Each petroleum system in Alberta has a different shape factor. Generally, the shape factors in the four petroleum systems stabilize with the increase of discovered pool numbers. For a log-geometric distribution, the shape factor becomes stable when discovered pool numbers exceed 50 and the shape factor is influenced by the exploration efficiency when the exploration efficiency is less than 1. The simulation results show that calculated shape factors increase with those of the parent distributions, and undiscovered oil and gas resources estimated through the log-geometric distribution extrapolation are smaller than the actual values. ?? 2010 International Association for Mathematical Geology.

  6. DDO 68: A Flea with Smaller Fleas that on Him Prey

    Science.gov (United States)

    Annibali, Francesca; Nipoti, Carlo; Ciotti, Luca; Tosi, Monica; Aloisi, Alessandra; Bellazzini, Michele; Cignoni, Michele; Cusano, Felice; Paris, Diego; Sacchi, Elena

    2016-08-01

    We present new photometry of the dwarf irregular galaxy DDO 68, one of the most metal-poor and least massive dwarfs, located in the Lynx-Cancer Void. The images were acquired with the Large Binocular Telescope in the g and r passbands and show unequivocally that DDO 68 has previously unknown stellar streams related to the accretion of at least two smaller companions: a flea with smaller fleas biting it, to put it in Jonathan Swift’s words (from Jonathan Swift’s On Poetry: a Rhapsody: So, naturalists observe, a flea/has smaller fleas that on him prey/and these have smaller still to bite em/and so proceed ad infinitum). Our data provide direct observational evidence of multiple galaxy merging occurring at very low galactic mass scales. We present the results of an N-body simulation of the interaction of three dwarf galaxies that reproduce well the main morphological features of DDO 68.

  7. A big alligator snacks on a smaller alligator

    Science.gov (United States)

    1998-01-01

    A large alligator attacks and eats a smaller one in a natural display of cannibalism. Although this event has been observed infrequently by Kennedy Space Center's staff photographers, it is common feeding behavior among the wild alligator population on the space center. Alligators are carnivorous and will eat any living thing that crosses their paths and is small enough for them to kill. For this reason, it is dangerous to feed wild alligators, and in Florida, it is also illegal. Kennedy Space Center is located on the Merritt Island National Wildlife Refuge which is operated by the U.S. Fish and Wildlife Service.

  8. Maximizing LSST's Scientific Return: Ensuring Participation from Smaller Institutions

    CERN Document Server

    Liu, Charles T; Pepper, Joshua; Rutkowski, Michael; Norman, Dara; Cruz, Kelle; Bochanski, John; Lee, Hyun-chul; Isler, Jedidah; Gizis, John; Smith, J Allyn; Moustakas, John; Wehner, Elizabeth; Alfred, Marcus; McGruder, Charles; Hoffman, Jennifer L; Kwitter, Karen; Carini, Michael; Bary, Jeff; Covey, Kevin R; Finn, Rose; Penprase, Brian; Gelderman, Richard; Schuler, Simon

    2014-01-01

    The remarkable scientific return and legacy of LSST, in the era that it will define, will not only be realized in the breakthrough science that will be achieved with catalog data. This Big Data survey will shape the way the entire astronomical community advances -- or fails to embrace -- new ways of approaching astronomical research and data. In this white paper, we address the NRC template questions 4,5,6,8 and 9, with a focus on the unique challenges for smaller, and often under-resourced, institutions, including institutions dedicated to underserved minority populations, in the efficient and effective use of LSST data products to maximize LSST's scientific return.

  9. Smaller superior temporal gyrus volume specificity in schizotypal personality disorder

    Science.gov (United States)

    Goldstein, Kim E.; Hazlett, Erin A.; New, Antonia S.; Haznedar, M. Mehmet; Newmark, Randall E.; Zelmanova, Yuliya; Passarelli, Vincent; Weinstein, Shauna R.; Canfield, Emily L.; Meyerson, David A.; Tang, Cheuk Y.; Buchsbaum, Monte S.; Siever, Larry J.

    2009-01-01

    Background Superior temporal gyrus (STG/BA22) volume is reduced in schizophrenia and to a milder degree in schizotypal personality disorder (SPD), representing a less severe disorder in the schizophrenia-spectrum. SPD and Borderline personality disorder (BPD) are severe personality disorders characterized by social and cognitive dysfunction. However, while SPD is characterized by social withdrawal/anhedonia, BPD is marked by hyper-reactivity to interpersonal stimuli and hyper-emotionality. This is the first morphometric study to directly compare SPD and BPD patients in temporal volume. Methods We compared three age-gender- and education-matched groups: 27 unmedicated SPD individuals with no BPD traits, 52 unmedicated BPD individuals with no SPD traits, and 45 healthy controls. We examined gray matter volume of frontal and temporal lobe Brodmann areas (BAs), and dorsal/ventral amygdala from 3T magnetic resonance imaging. Results In the STG, an auditory association area reported to be dysfunctional in SPD and BPD, the SPD patients had significantly smaller volume than healthy controls and BPD patients. No group differences were found between BPD patients and controls. Smaller BA22 volume was associated with greater symptom severity in SPD patients. Reduced STG volume may be an important endophenotype for schizophrenia-spectrum disorders. SPD is distinct from BPD in terms of STG volume abnormalities which may reflect different underlying pathophysiological mechanisms and could help discriminate between them. PMID:19473820

  10. VLSI technology for smaller, cheaper, faster return link systems

    Science.gov (United States)

    Nanzetta, Kathy; Ghuman, Parminder; Bennett, Toby; Solomon, Jeff; Dowling, Jason; Welling, John

    1994-01-01

    Very Large Scale Integration (VLSI) Application-specific Integrated Circuit (ASIC) technology has enabled substantially smaller, cheaper, and more capable telemetry data systems. However, the rapid growth in available ASIC fabrication densities has far outpaced the application of this technology to telemetry systems. Available densities have grown by well over an order magnitude since NASA's Goddard Space Flight Center (GSFC) first began developing ASIC's for ground telemetry systems in 1985. To take advantage of these higher integration levels, a new generation of ASIC's for return link telemetry processing is under development. These new submicron devices are designed to further reduce the cost and size of NASA return link processing systems while improving performance. This paper describes these highly integrated processing components.

  11. Portal pressure liver transplantation utilizing smaller grafts than before.

    Science.gov (United States)

    Ogura, Yasuhiro; Hori, Tomohide; El Moghazy, Walid M; Yoshizawa, Atsushi; Oike, Fumitaka; Mori, Akira; Kaido, Toshimi; Takada, Yasutsugu; Uemoto, Shinji

    2010-06-01

    To prevent small-for-size syndrome in adult-to-adult living donor liver transplantation (A-LDLT), larger grafts (ie, right lobe grafts) have been selected in many transplant centers. However, some centers are investigating the benefits of portal pressure modulation. Five hundred sixty-six A-LDLT procedures using right or left lobe grafts were performed between 1998 and 2008. In 2006, we introduced intentional portal pressure control, and we changed the graft selection criteria to include a graft/recipient weight ratio >0.7% instead of the original value of >0.8%. All recipients were divided into period I (1998-2006, the era of unintentional portal pressure control; n = 432) and period II (2006-2008, the era of intentional portal pressure control; n = 134). The selection of small-for-size grafts increased from 7.8% to 23.9%, and the selection of left lobe grafts increased from 4.9% to 32.1%. Despite the increase in the number of smaller grafts in period II, 1-year patient survival was significantly improved (87.9% versus 76.2%). In 129 recipients in period II, portal pressure was monitored. Patients with a portal pressure or=15 mm Hg (n = 43, 66.3%). The recovery from hyperbilirubinemia and coagulopathy after transplantation was significantly better in patients with a portal pressure graft-based A-LDLT to controlled portal pressure-based A-LDLT with smaller grafts. A portal pressure <15 mm Hg seems to be a key for successful A-LDLT.

  12. An Analysis of Substance Use among Adolescents from Smaller Places.

    Science.gov (United States)

    Donnermeyer, Joseph F.; Scheer, Scott D.

    2001-01-01

    Examines substance use trends among rural 12th-grade students, 1976-97, based on the national triennial study "Monitoring the Future." Finds that youth from more rural locations generally displayed lower rates of substance use, but as urbanization spread, differences declined. Compares data on farm, rural nonfarm, and small-town youth in both…

  13. Sexual selection and senescence: male size-dimorphic ungulates evolved relatively smaller molars than females.

    Science.gov (United States)

    Carranza, Juan; Pérez-Barbería, F Javier

    2007-09-01

    As a general rule, males of sexually dimorphic ungulate species have evolved larger body size than females but shorter reproductive life spans as elements of their strategy for intrasexual competition for mating opportunities. Evolutionary theories of senescence predict that the durability of somatic structures should relate to the length of reproductive life span. This prediction has recently been tested for red deer (Cervus elaphus): molariform teeth of males are smaller and less durable than those of females, which corresponds with sex differences in reproductive life span. However, general evidence that male teeth are smaller than expected by allometric rules as a consequence of sexual selection for increasing male body mass requires an interspecific comparison between dimorphic and nondimorphic ungulates. Here we investigate the relationship between cheek-teeth size (occlusal surface area; OSA) and body mass in 123 species of extant ungulates. We found lower slopes for dimorphic species compared with nondimorphic ones and smaller OSA, relative to body mass, in males of dimorphic species compared with females of dimorphic species. Rates of evolution of OSA relative to rates of evolution of body mass were greater in females than in males and also greater in nondimorphic than in dimorphic species. Our results are consistent with the hypothesis that sexual selection in polygynous male ungulates favors body size more than tooth size, with possible consequences in male senescence via early depletion of male teeth compared to females.

  14. Media bias under direct and indirect government control: when is the bias smaller?

    OpenAIRE

    Abhra Roy

    2015-01-01

    We present an analytical framework to compare media bias under direct and indirect government control. In this context, we show that direct control can lead to a smaller bias and higher welfare than indirect control. We further show that the size of the advertising market affects media bias only under direct control. Media bias, under indirect control, is not affected by the size of the advertising market.

  15. More, smaller bacteria in response to ocean's warming?

    KAUST Repository

    Moran, Xose Anxelu G.

    2015-06-10

    Heterotrophic bacteria play a major role in organic matter cycling in the ocean. Although the high abundances and relatively fast growth rates of coastal surface bacterioplankton make them suitable sentinels of global change, past analyses have largely overlooked this functional group. Here, time series analysis of a decade of monthly observations in temperate Atlantic coastal waters revealed strong seasonal patterns in the abundance, size and biomass of the ubiquitous flow-cytometric groups of low (LNA) and high nucleic acid (HNA) content bacteria. Over this relatively short period, we also found that bacterioplankton cells were significantly smaller, a trend that is consistent with the hypothesized temperature-driven decrease in body size. Although decadal cell shrinking was observed for both groups, it was only LNA cells that were strongly coherent, with ecological theories linking temperature, abundance and individual size on both the seasonal and interannual scale. We explain this finding because, relative to their HNA counterparts, marine LNA bacteria are less diverse, dominated by members of the SAR11 clade. Temperature manipulation experiments in 2012 confirmed a direct effect of warming on bacterial size. Concurrent with rising temperatures in spring, significant decadal trends of increasing standing stocks (3% per year) accompanied by decreasing mean cell size (-1% per year) suggest a major shift in community structure, with a larger contribution of LNA bacteria to total biomass. The increasing prevalence of these typically oligotrophic taxa may severely impact marine foodwebs and carbon fluxes by an overall decrease in the efficiency of the biological pump. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  16. Neonatal morbidity in growth-discordant monochorionic twins: comparison between the larger and the smaller twin.

    Science.gov (United States)

    Lopriore, Enrico; Sluimers, Carolien; Pasman, Suzanne A; Middeldorp, Johanna M; Oepkes, Dick; Walther, Frans J

    2012-08-01

    Fetal growth restriction in singletons has been shown to enhance fetal lung maturation and reduce the risk of respiratory distress syndrome due to increased endogenous steroid production. However, data on lung maturation in growth-discordant monochorionic (thus, identical) twins are lacking. Our objective was to compare the risk of severe neonatal morbidity between the larger and the smaller twin in monochorionic twins with birth weight discordance (BWD). We included in the study all consecutive monochorionic diamniotic pregnancies with severe BWD (≥25%) and two live-born twins delivered at our center (n=47 twin pairs). We compared the incidence of neonatal morbidity, particularly respiratory distress syndrome (RDS), and cerebral lesions between the larger and the smaller co-twin. The incidence of severe neonatal morbidity in the larger and smaller twin was 38% (18/47) and 19% (9/47), respectively (odds ratio (OR) 2.66, 95% confidence interval (CI) 0.94-7.44) and was due primarily to the higher incidence of RDS, 32% (15/47) and 6% (3/47), respectively (OR 6.88, 95% CI 1.66-32.83). In conclusion, this study shows that the larger twin in monochorionic twin pairs with BWD is at increased risk of severe neonatal morbidity, particularly RDS, compared to the smaller twin.

  17. Does multiple seed loading in Blue Jays result in selective dispersal of smaller acorns?

    Science.gov (United States)

    Bartlow, Andrew W; Kachmar, Michael; Lichti, Nathanael; Swihart, Robert K; Stratford, Jeffrey A; Steele, Michael A

    2011-09-01

    Studies from both tropical and temperate systems show that scatter-hoarding rodents selectively disperse larger seeds farther from their source than smaller seeds, potentially increasing seedling establishment in larger-seeded plants. Size-biased dispersal is evident in many oaks (Quercus) and is true both across and within species. Here, we predict that intraspecifc variation in seed size also influences acorn dispersal by the Blue Jay (Cyanocitta cristata Linnaeus), but in an opposite manner. Blue Jays are gape-limited and selectively disperse smaller acorn species (e.g. pin oaks [Quercus palustris Münchh]), but often carry several acorns in their crop during a single dispersal event. We predict that jays foraging on smaller acorns will load more seeds per trip and disperse seeds to greater distances than when single acorns are carried in the bill. To test this, we presented free-ranging Blue Jays with pin oak acorns of different sizes over a 2-year period. In each of 16 experimental trials, we monitored the birds at a feeding station with remote cameras and determined the number of acorns removed and the distance acorns were dispersed when cached. Jays were significantly more likely to engage in multiple seed loading with smaller seeds in both years of the study. During the second year, these smaller acorns were dispersed farther than larger acorns, and during the first year, larger acorns were dispersed farther, revealing an inconsistent response to seed size during our study. We suggest that in some circumstances, multiple seed loading by Blue Jays may favor dispersal in some plant species.

  18. DDO 68: A flea with smaller fleas that on him prey

    CERN Document Server

    Annibali, F; Ciotti, L; Tosi, M; Aloisi, A; Bellazzini, M; Cignoni, M; Cusano, F; Paris, D; Sacchi, E

    2016-01-01

    We present new photometry of the dwarf irregular galaxy DDO 68, one of the most metal-poor and least massive dwarfs, located in the Lynx-Cancer Void. The images were acquired with the Large Binocular Telescope in the g and r passbands, and show unequivocally that DDO 68 has previously unknown stellar streams related to the accretion of at least two smaller companions: a flea with smaller fleas biting it, to put it in Jonathan Swift's words. Our data provide direct observational evidence of multiple merging occurring at very low galactic mass scales. We present the results of an N-body simulation of the interaction of three dwarf galaxies which reproduces well the main morphological features of DDO 68.

  19. DEVELOPMENT OF NEW SERVICES IN SMALLER ORGANISATIONS: THEY DO JUST HAPPEN

    Directory of Open Access Journals (Sweden)

    Patrik Gottfridsson

    2011-10-01

    Full Text Available The aim of this study is to investigate how new services are actually developed in real life in small companies. Although conventional models of service development emphasise the importance of formal and structured processes, it is unclear whether most service development really is conducted in this way, and whether these formal models might merely represent theoretical structures that have been retrospectively imposed on the actual process. In particular, it is unclear whether the conventional view of formal and structured processes is applicable to smaller organisations with fewer employees. The present study therefore presents the findings from in-depth case studies of service development in eleven small Swedish companies. The study concludes that that it is difficult to identify any clear intention to pursue formal development processes in the companies studied here. Rather, service development could generally be described as ‘unstructured’ in all phases (planning, development, and market launch. Moreover, these phases overlap and impinge on one another in a flexible, unstructured, and informal manner. The study examines and explains the reasons for this generally unstructured approach to service development in smaller firms.

  20. Enhanced MRI of breast cancer smaller than 3 cm

    Energy Technology Data Exchange (ETDEWEB)

    Ikeda, Yukio; Yoshida, Shouji (Hyogo Medical Center for Adults (Japan)); Narabayashi, Isamu (and others)

    1991-11-01

    Twenty-two patients with breast cancers were studied using magnetic resonance (MR) imaging with a cylindrical surface coil at 1.5 Tesla. All were examined with the FE sequence and Gd-DTPA as a contrast medium. These images were compared with micrographs of the specimens. All cancers were enhanced clearly, and demarcated margins or spiculations of the tumors were seen as clearly on MR images as on micrographs of the specimens. In 12 patients (9 carcinomas, 2 fibroadenomas and 1 benign phyllodes tumor), dynamic studies were performed after the intravenous injection of Gd-DTPA. All nine carcinomas showed enhancement characterized by a sudden increase in signal intensity on the order of 100% or more with the first 2 minutes after injection. Two fibroadenomas were enhanced slowly. Thirteen patients with breast cancers were examined with several sequences (FE, T{sub 1}-weighted SE, T{sub 2}-weighted SE and STIR) with or without Gd-DTPA. The most clearly delineated images of the tumors were those of FE images with Gd-DTPA enhancement. A phantom constituted of various concentrations of Gd-DTPA in 20% albumin solution was measured by signal intensities with T{sub 1}-weighted SE sequence and FE sequence. The ratio of enhancement of the 20% albumin solution relative to the Gd-DTPA concentration was higher with the FE sequence than with the SE sequence. The sensitivity of the FE sequence to Gd-DTPA enhancement was 1.5 times that of the SE sequence under the usual concentration of Gd-DTPA. (author).

  1. Ultrafast acoustics in the middle UV range: coherent phonons at higher frequencies and in smaller objects.

    Science.gov (United States)

    Ayrinhac, S; Devos, A; Le Louarn, A; Mante, P-A; Emery, P

    2010-10-15

    We show that the propagation of coherent acoustic phonons generated by femtosecond optical excitation can be clearly resolved using a probe laser in the middle UV (MUV) range. The MUV probe is easily produced from a high-repetition-rate femtosecond laser and a homemade frequency tripler. We present various experimental results that demonstrate efficient and high frequency detection of acoustic phonons. Thus, we show that the MUV range offers a unique way to reach higher frequencies and probe smaller objects in ultrafast acoustics.

  2. Addressing the multiplication makes bigger and division makes smaller misconceptions via prediction and clickers

    Science.gov (United States)

    Lim, Kien H.

    2011-12-01

    This article presents a lesson that uses prediction items, clickers and visuals via PowerPoint slides to help prospective middle-school teachers address two common misconceptions: multiplication makes bigger and division makes smaller (MMB-DMS). Classroom research was conducted to explore the viability of such a lesson. Results show that the lesson was effective in creating awareness that multiplication does not always make bigger and division does not always makes smaller, uncovering students' misconceptions, and providing opportunities for students to learn from mistakes. Students liked the activity for various reasons, such as getting to learn certain mathematical ideas, to think about the problems, to work in groups and to have fun. The lesson was implemented slightly differently in two classes. The class with an additional phase involving prediction and voting via clickers in the PowerPoint lesson showed a gain of 36 points (an effect size of 1.3 standard deviations, SDs) from the pre-test to the exit-test whereas, the comparison class showed a gain of 25 points (an effect size of 0.87 SDs). In terms of students' written responses with regards to addressing the MMB-DMS misconceptions, there was however not much difference between the two classes.

  3. The problem is not just sample size: the consequences of low base rates in policing experiments in smaller cities.

    Science.gov (United States)

    Hinkle, Joshua C; Weisburd, David; Famega, Christine; Ready, Justin

    2013-01-01

    Hot spots policing is one of the most influential police innovations, with a strong body of experimental research showing it to be effective in reducing crime and disorder. However, most studies have been conducted in major cities, and we thus know little about whether it is effective in smaller cities, which account for a majority of police agencies. The lack of experimental studies in smaller cities is likely in part due to challenges designing statistically powerful tests in such contexts. The current article explores the challenges of statistical power and "noise" resulting from low base rates of crime in smaller cities and provides suggestions for future evaluations to overcome these limitations. Data from a randomized experimental evaluation of broken windows policing in hot spots are used to illustrate the challenges that low base rates present for evaluating hot spots policing programs in smaller cities. Analyses show low base rates make it difficult to detect treatment effects. Very large effect sizes would be required to reach sufficient power, and random fluctuations around low base rates make detecting treatment effects difficult, irrespective of power, by masking differences between treatment and control groups. Low base rates present strong challenges to researchers attempting to evaluate hot spots policing in smaller cities. As such, base rates must be taken directly into account when designing experimental evaluations. The article offers suggestions for researchers attempting to expand the examination of hot spots policing and other microplace-based interventions to smaller jurisdictions.

  4. Generalized BPS magnetic monopoles

    CERN Document Server

    Casana, R; da Hora, E

    2012-01-01

    We show the existence of Bogomol'nyi-Prasad-Sommerfield (BPS) magnetic monopoles in a generalized Yang-Mills-Higgs model which is controlled by two positive functions. This effective model, in principle, would describe the dynamics of the nonabelian fields in a chromoelectric media. We check the consistency of our generalized construction by analyzing an explicit case ruled by a real parameter. We also use the well-known spherically symmetric Ansatz to attain the corresponding self-dual equations describing the topological solutions. The overall conclusion is that the new solutions behave around the canonical one, with smaller or greater characteristic length.

  5. Diversity of larger consumers enhances interference competition effects on smaller competitors.

    Science.gov (United States)

    Nascimento, Francisco J A; Karlson, Agnes M L; Näslund, Johan; Elmgren, Ragnar

    2011-06-01

    Competition between large and small species for the same food is common in a number of ecosystems including aquatic ones. How diversity of larger consumers affects the access of smaller competitors to a limiting resource is not well understood. We tested experimentally how species richness (0-3 spp.) of benthic deposit-feeding macrofauna changes meiofaunal ostracods' incorporation of fresh organic matter from a stable-isotope-labeled cyanobacterial bloom, using fauna from the species-poor Baltic Sea. Presence of macrofauna mostly decreased meiofaunal incorporation of bloom material, depending on the macrofauna species present. As expected, the species identity of macrofauna influenced the incorporation of organic matter by meiofauna. Interestingly, our results show that, in addition, species richness of the macrofauna significantly reduced meiofauna incorporation of freshly settled nitrogen and carbon. With more than one macrofauna species, the reduction was always greater than expected from the single-species treatments. Field data from the Baltic Sea showed a negative correlation between macrofauna diversity and meiofaunal ostracod abundance, as expected from the experimental results. We argue that this is caused by interference competition, due to spatial niche differentiation between macrofauna species reducing the sediment volume in which ostracods can feed undisturbed by larger competitors. Interference from macrofauna significantly reduces organic matter incorporation by meiofauna, indicating that diversity of larger consumers is an important factor controlling the access of smaller competitors to a limiting food resource.

  6. Toll-like receptor 4 deficiency: Smaller infarcts, but nogain in function

    Directory of Open Access Journals (Sweden)

    Hoeft Andreas

    2007-06-01

    Full Text Available Abstract Backgound It has been reported that Toll-like receptor 4 (TLR4 deficiency reduces infarct size after myocardial ischemia/reperfusion (MI/R. However, measurement of MI/R injury was limited and did not include cardiac function. In a chronic closed-chest model we assessed whether cardiac function is preserved in TLR4-deficient mice (C3H/HeJ following MI/R, and whether myocardial and systemic cytokine expression differed compared to wild type (WT. Results Infarct size (IS in C3H/HeJ assessed by TTC staining after 60 min ischemia and 24h reperfusion was significantly smaller than in WT. Despite a smaller infarct size, echocardiography showed no functional difference between C3H/HeJ and WT. Left-ventricular developed pressure measured with a left-ventricular catheter was lower in C3H/HeJ (63.0 ± 4.2 mmHg vs. 77.9 ± 1.7 mmHg in WT, p Conclusion These results demonstrate that, although a mutant TLR4 signaling cascade reduces myocardial IS and serum cytokine levels, it does not preserve myocardial function. The change in inflammatory response, secondary to a non-functional TLR-4 receptor, may contribute to the observed dichotomy between infarct size and function in the TLR-4 mutant mouse.

  7. Detection of airborne Stachybotrys chartarum macrocyclic trichothecene mycotoxins on particulates smaller than conidia.

    Science.gov (United States)

    Brasel, T L; Douglas, D R; Wilson, S C; Straus, D C

    2005-01-01

    Highly respirable particles (diameter, water-damaged buildings. The presence of airborne Stachybotrys chartarum trichothecene mycotoxins on particles smaller than conidia (e.g., fungal fragments) was therefore investigated. Cellulose ceiling tiles with confluent Stachybotrys growth were placed in gas-drying containers through which filtered air was passed. Exiting particulates were collected by using a series of polycarbonate membrane filters with decreasing pore sizes. Scanning electron microscopy was employed to determine the presence of conidia on the filters. A competitive enzyme-linked immunosorbent assay (ELISA) specific for macrocyclic trichothecenes was used to analyze filter extracts. Cross-reactivity to various mycotoxins was examined to confirm the specificity. Statistically significant (P trichothecenes at concentrations of 50 and 5 ng/ml and 500 pg/ml (58.4 to 83.5% inhibition). Of the remaining toxins tested, only verrucarol and diacetylverrucarol (nonmacrocyclic trichothecenes) demonstrated significant binding (18.2 and 51.7% inhibition, respectively) and then only at high concentrations. The results showed that extracts from conidium-free filters demonstrated statistically significant (P trichothecene mycotoxins can become airborne in association with intact conidia or smaller particles. These findings may have important implications for indoor air quality assessment.

  8. Smaller calcite lattice deformation caused by occluded organic material in coccoliths than in mollusk shell

    DEFF Research Database (Denmark)

    Frølich, Simon; Sørensen, Henning Osholm; Hakim, Sepideh Sadat

    2015-01-01

    coccoliths. We compare the results with data on chalk from the extensively studied mussel Pinna nobilis that served as a control. Using high resolution synchrotron powder X-ray diffraction combined with in situ heating, the influence of organic compounds on the structure of the inorganic phase was probed...... and the coccolithophorids. These differences were reflected in lattice deformation (macrostrain), structure (microstrain), and atomic disorder distributions (δorganic). The influence of the biological macromolecules on the inorganic phase was consistently smaller in the P. carterae compared to P. nobilis....... Two heating cycles allow us to differentiate the effects of thermal agitation and organic molecules. Single peak analysis and Rietveld refinement were combined to show significant differences resulting from the occluded biomolecules on the mineral phase in biogenic calcite in the mollusk shell...

  9. Scattering and Absorption Properties of Polydisperse Wavelength-sized Particles Covered with Much Smaller Grains

    Science.gov (United States)

    Dlugach, Jana M.; Mishchenko, Michael I.; Mackowski, Daniel W.

    2012-01-01

    Using the results of direct, numerically exact computer solutions of the Maxwell equations, we analyze scattering and absorption characteristics of polydisperse compound particles in the form of wavelength-sized spheres covered with a large number of much smaller spherical grains.The results pertain to the complex refractive indices1.55 + i0.0003,1.55 + i0.3, and 3 + i0.1. We show that the optical effects of dusting wavelength-sized hosts by microscopic grains can vary depending on the number and size of the grains as well as on the complex refractive index. Our computations also demonstrate the high efficiency of the new superposition T-matrix code developed for use on distributed memory computer clusters.

  10. Smaller-loss planar SPP transmission line than conventional microstrip in microwave frequencies.

    Science.gov (United States)

    Zhang, Hao Chi; Zhang, Qian; Liu, Jun Feng; Tang, Wenxuan; Fan, Yifeng; Cui, Tie Jun

    2016-03-17

    Transmission line is a basic component in all passive devices, integrated circuits, and systems. Microstrip is the most popular transmission line in the microwave and millimeter-wave frequencies, and has been widely used in current electronic devices, circuits, and systems. One of the important issues to be solved in such applications is the relatively large transmission loss of microstrip. Here, we propose a method to reduce the loss of microwave transmission line based on the designable wavenumber of spoof surface plasmon polaritons (SPPs). Using this characteristic, we analyze and experimentally demonstrate the low-loss feature of the SPP transmission line through the perturbation method and S-parameter measurements, respectively. Both simulation and experimental results show that the SPP transmission line has much smaller transmission loss than traditional microstrip with the same size in the microwave frequencies. Hence, the spoof SPP transmission line may make a big step forward in the low-loss circuits and systems.

  11. The Composition of Business Establishment in Smaller and Larger Communities in Canada

    OpenAIRE

    Mendelson, Robert

    1999-01-01

    Between 1993 and 1996 there was a large number of business establishment starts in smaller and larger communities in Canada, indicating significant business establishment development in the post recessionary period of the 1990s. Between 1993 and 1996 smaller communities had a larger ratio of smaller establishments (under 10 employees) to population than larger communities. In today's economy, new establishments tend to have fewer employees (under 10 employees) and are located in the service a...

  12. Smaller external notebook mice have different effects on posture and muscle activity.

    Science.gov (United States)

    Oude Hengel, Karen M; Houwink, Annemieke; Odell, Dan; van Dieën, Jaap H; Dennerlein, Jack T

    2008-07-01

    Extensive computer mouse use is an identified risk factor for computer work-related musculoskeletal disorders; however, notebook computer mouse designs of varying sizes have not been formally evaluated but may affect biomechanical risk factors. Thirty adults performed a set of mouse tasks with five notebook mice, ranging in length from 75 to 105 mm and in width from 35 to 65 mm, and a reference desktop mouse. An electro-magnetic motion analysis system measured index finger (metacarpophalangeal joint), wrist and forearm postures, and surface electromyography measured muscle activity of three extensor muscles in the forearm and the first dorsal interosseus. The smallest notebook mice were found to promote less neutral postures (up to 3.2 degrees higher metacarpophalangeal joint adduction; 6.5 degrees higher metacarpophalangeal joint flexion, 2.3 degrees higher wrist extension) and higher muscle activity (up to 4.1% of maximum voluntary contraction higher wrist extensor muscle activity). Participants with smaller hands had overall more non-neutral postures than participants with larger hands (up to 5.6 degrees higher wrist extension and 5.9 degrees higher pronation); while participants with larger hands were more influenced by the smallest notebook mice (up to 3.6 degrees higher wrist extension and 5.5% of maximum voluntary contraction higher wrist extensor values). Self-reported ratings showed that while participants preferred smaller mice for portability; larger mice scored higher on comfort and usability. The smallest notebook mice increased the intensity of biomechanical exposures. Longer term mouse use could enhance these differences, having a potential impact on the prevention of work-related musculoskeletal disorders.

  13. Slower gait, slower information processing and smaller prefrontal area in older adults.

    NARCIS (Netherlands)

    Rosano, C.; Studenski, S.A.; Aizenstein, H.J.; Boudreau, R.M.; Longstreth Jr, W.T.; Newman, A.B.

    2012-01-01

    BACKGROUND: Slower gait in older adults is related to smaller volume of the prefrontal area (PFAv). The pathways underlying this association have not yet been explored. Understanding slowing gait could help improve function in older age. We examine whether the association between smaller PFAv and

  14. Slower gait, slower information processing and smaller prefrontal area in older adults.

    NARCIS (Netherlands)

    Rosano, C.; Studenski, S.A.; Aizenstein, H.J.; Boudreau, R.M.; Longstreth Jr, W.T.; Newman, A.B.

    2012-01-01

    BACKGROUND: Slower gait in older adults is related to smaller volume of the prefrontal area (PFAv). The pathways underlying this association have not yet been explored. Understanding slowing gait could help improve function in older age. We examine whether the association between smaller PFAv and sl

  15. Smaller Cigarette Pack as a Commitment to Smoke Less? Insights from Behavioral Economics.

    Directory of Open Access Journals (Sweden)

    Joachim Marti

    Full Text Available Cigarettes are commonly sold in packs of 20 units and therefore little is known about the potential impact of pack size on consumption. Using insights from behavioral economics, we suggest that cigarette packs smaller than the standard size may help some smokers cut back and/or quit, consistent with their long-term goals. Results from an online hypothetical purchase experiment conducted in a sample of US smokers reveal that over a third of smokers are willing to pay a price premium to purchase in smaller quantities. Further, a desire to quit smoking and high self-control is associated with preference for a smaller pack. While we provide some preliminary evidence that smaller packs may be beneficial to certain types of smokers, further research should be conducted to assess whether the smaller pack size should be considered in the arsenal of tobacco control policies to help current smokers quit (JEL: I18; I12; D12.

  16. Smaller Cigarette Pack as a Commitment to Smoke Less? Insights from Behavioral Economics.

    Science.gov (United States)

    Marti, Joachim; Sindelar, Jody

    2015-01-01

    Cigarettes are commonly sold in packs of 20 units and therefore little is known about the potential impact of pack size on consumption. Using insights from behavioral economics, we suggest that cigarette packs smaller than the standard size may help some smokers cut back and/or quit, consistent with their long-term goals. Results from an online hypothetical purchase experiment conducted in a sample of US smokers reveal that over a third of smokers are willing to pay a price premium to purchase in smaller quantities. Further, a desire to quit smoking and high self-control is associated with preference for a smaller pack. While we provide some preliminary evidence that smaller packs may be beneficial to certain types of smokers, further research should be conducted to assess whether the smaller pack size should be considered in the arsenal of tobacco control policies to help current smokers quit (JEL: I18; I12; D12).

  17. CERN on show

    CERN Multimedia

    2012-01-01

    Last week I was in Ankara to discuss Turkish accession to CERN, and to take part in the opening of CERN’s main travelling exhibition at the Middle East Technical University. I was astonished at the crowds of people the exhibition drew in, and I’m told that it’s a similar story wherever it goes. Our smaller exhibition stands are also much in demand across our Member States.   You don’t have to travel to Ankara, however, to experience the same phenomenon – just go to Building 33 any time from Monday to Saturday and you’ll get the idea. But although we’ve worked hard over recent years to increase our capacity for visits to a level approaching 80,000 per year, there’s still a long waiting list. And that’s a problem. The success of the Visits Service rests on the goodwill of all the CERNois who volunteer to be guides, as well as those who graciously allow increasing numbers of visitors into their workplaces...

  18. Indian Reservations, RBD, Published in 1985, Smaller than 1:100000 scale, BIA Western Regional Office.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Indian Reservations dataset, published at Smaller than 1:100000 scale, was produced all or in part from Other information as of 1985. It is described as 'RBD'....

  19. High proportion of smaller ranged hummingbird species coincides with ecological specialization across the Americas

    DEFF Research Database (Denmark)

    Sonne, Jesper; Martín González, Ana M.; Maruyama, Pietro K.

    2016-01-01

    Ecological communities that experience stable climate conditions have been speculated to preserve more specialized interspecific associations and have higher proportions of smaller ranged species (SRS). Thus, areas with disproportionally large numbers of SRS are expected to coincide geographicall...

  20. 100-Year Floodplains, Floodplain, Published in 2000, Smaller than 1:100000 scale, Taylor County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at Smaller than 1:100000 scale, was produced all or in part from Hardcopy Maps information as of 2000. It is described...

  1. Wind Power, Published in 2005, Smaller than 1:100000 scale, Garrett County Planning & Land Development.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wind Power dataset, published at Smaller than 1:100000 scale, was produced all or in part from Published Reports/Deeds information as of 2005. Data by this...

  2. Road Maintenance Districts, Published in 2006, Smaller than 1:100000 scale, Nevada Department of Transportation.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Road Maintenance Districts dataset, published at Smaller than 1:100000 scale, was produced all or in part from Published Reports/Deeds information as of 2006....

  3. Cellular Phone Towers, Published in 1990, Smaller than 1:100000 scale, Pitt County GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at Smaller than 1:100000 scale, was produced all or in part from Published Reports/Deeds information as of 1990. Data...

  4. Broadcast Service Areas, Cable, Published in 1990, Smaller than 1:100000 scale, Pitt County GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Broadcast Service Areas, Cable dataset, published at Smaller than 1:100000 scale, was produced all or in part from Published Reports/Deeds information as of...

  5. Smaller population size at the MRCA time for stationary branching processes

    CERN Document Server

    Chen, Yu-Ting

    2010-01-01

    We present an elementary model of random size varying population given by a stationary continuous state branching process. For this model we compute the joint distribution of: the time to the most recent common ancestor, the size of the current population and the size of the population just before the most recent common ancestor (MRCA). In particular we show a natural mild bottleneck effect as the size of the population just before the MRCA is stochastically smaller than the size of the current population. We also compute the number of old families which corresponds to the number of individuals involved in the last coalescent event of the genealogical tree. By studying more precisely the genealogical structure of the population, we get asymptotics for the number of ancestors just before the current time. We give explicit computations in the case of the quadratic branching mechanism. In this case, the size of the population at the MRCA is, in mean, less by 1/3 than size of the current population size. We also ...

  6. Randomized denoising autoencoders for smaller and efficient imaging based AD clinical trials

    Science.gov (United States)

    Ithapu, Vamsi K.; Singh, Vikas; Okonkwo, Ozioma; Johnson, Sterling C.

    2015-01-01

    There is growing body of research devoted to designing imaging-based biomarkers that identify Alzheimer’s disease (AD) in its prodromal stage using statistical machine learning methods. Recently several authors investigated how clinical trials for AD can be made more efficient (i.e., smaller sample size) using predictive measures from such classification methods. In this paper, we explain why predictive measures given by such SVM type objectives may be less than ideal for use in the setting described above. We give a solution based on a novel deep learning model, randomized denoising autoencoders (rDA), which regresses on training labels y while also accounting for the variance, a property which is very useful for clinical trial design. Our results give strong improvements in sample size estimates over strategies based on multi-kernel learning. Also, rDA predictions appear to more accurately correlate to stages of disease. Separately, our formulation empirically shows how deep architectures can be applied in the large d, small n regime — the default situation in medical imaging. This result is of independent interest. PMID:25485413

  7. Smaller Real Regional Income Gap than Nominal Income Gap: A Price-adjusted Study

    Institute of Scientific and Technical Information of China (English)

    Xiaojuan Jiang; Hui Li

    2006-01-01

    Two factors determining the level of living in different areas are income level and price level.Current studies on regional gaps concentrate on the gap in income levels. The present paper studies the impact of the two variables on the real living standards in different regions, with the real gap in the living standards calculated with price adjustment by taking into consideration only the deviations brought about by cash income. The basic conclusion is that, despite China's economy having witnessed rapid growth, the statistics at the macro level cannot disguise the obvious gaps among regions; therefore, as a result of the impact of income and price, the real gap in the living standards among different regions is smaller than the gap indicated by the nominal income level. As people are sensitive to cash income level, they have a low sensitivity to changes in real purchasing power. In other words, in areas that have the same real income levels, people tend to think that people live better when the nominal income and price are both high. The differences in price indices among different regions show that the same cash income can get different goods and services in different regions. This explains the rationale of the existence of floating workers among different regions. On this basis, we predict that people working in high-income areas who enjoy higher levels of social security might prefer to live in low-priceareas after retirement if the social security payment method becomes more flexible.

  8. Randomized denoising autoencoders for smaller and efficient imaging based AD clinical trials.

    Science.gov (United States)

    Ithapul, Vamsi K; Singh, Vikas; Okonkwo, Ozioma; Johnson, Sterling C

    2014-01-01

    There is growing body of research devoted to designing imaging-based biomarkers that identify Alzheimer's disease (AD) in its prodromal stage using statistical machine learning methods. Recently several authors investigated how clinical trials for AD can be made more efficient (i.e., smaller sample size) using predictive measures from such classification methods. In this paper, we explain why predictive measures given by such SVM type objectives may be less than ideal for use in the setting described above. We give a solution based on a novel deep learning model, randomized denoising autoencoders (rDA), which regresses on training labels y while also accounting for the variance, a property which is very useful for clinical trial design. Our results give strong improvements in sample size estimates over strategies based on multi-kernel learning. Also, rDA predictions appear to more accurately correlate to stages of disease. Separately, our formulation empirically shows how deep architectures can be applied in the large d, small n regime--the default situation in medical imaging. This result is of independent interest.

  9. Origin of giant viruses from smaller DNA viruses not from a fourth domain of cellular life.

    Science.gov (United States)

    Yutin, Natalya; Wolf, Yuri I; Koonin, Eugene V

    2014-10-01

    The numerous and diverse eukaryotic viruses with large double-stranded DNA genomes that at least partially reproduce in the cytoplasm of infected cells apparently evolved from a single virus ancestor. This major group of viruses is known as Nucleocytoplasmic Large DNA Viruses (NCLDV) or the proposed order Megavirales. Among the "Megavirales", there are three groups of giant viruses with genomes exceeding 500kb, namely Mimiviruses, Pithoviruses, and Pandoraviruses that hold the current record of viral genome size, about 2.5Mb. Phylogenetic analysis of conserved, ancestral NLCDV genes clearly shows that these three groups of giant viruses have three distinct origins within the "Megavirales". The Mimiviruses constitute a distinct family that is distantly related to Phycodnaviridae, Pandoraviruses originate from a common ancestor with Coccolithoviruses within the Phycodnaviridae family, and Pithoviruses are related to Iridoviridae and Marseilleviridae. Maximum likelihood reconstruction of gene gain and loss events during the evolution of the "Megavirales" indicates that each group of giant viruses evolved from viruses with substantially smaller and simpler gene repertoires. Initial phylogenetic analysis of universal genes, such as translation system components, encoded by some giant viruses, in particular Mimiviruses, has led to the hypothesis that giant viruses descend from a fourth, probably extinct domain of cellular life. The results of our comprehensive phylogenomic analysis of giant viruses refute the fourth domain hypothesis and instead indicate that the universal genes have been independently acquired by different giant viruses from their eukaryotic hosts.

  10. Ethanol injection is highly effective for hepatocellular carcinoma smaller than 2 cm

    Institute of Scientific and Technical Information of China (English)

    Maurizio Pompili; Gian Ludovico Rapaccini; Erica Nicolardi; Valeria Abbate; Luca Miele; Laura Riccardi; Marcello Covino; Nicoletta De Matthaeis; Antonio Grieco; Raffaele Landolfi

    2011-01-01

    AIM: To analyze the long-term prognosis in a cohort of western cirrhotic patients with single hepatocellular carcinoma treated with ethanol injection. METHODS: One-hundred forty-eight patients with solitary hepatocellular carcinoma were enrolled. The tumor diameter was lower than 2 cm in 47 patients but larger in the remaining 101 patients. The impact of some pretreatment clinical and laboratory parameters and of tumor recurrence on patients' survival was assessed. RESULTS: Among the pre-treatment parameters, only a tumor diameter of less than 2 cm was an independent prognostic factor of survival. The occurrence of new nodules in other liver segments and the neoplastic portal invasion were linked to a poorer prognosis at univariate analysis. Patients with a single hepatocellular carcinoma smaller than 2 cm showed a better 5-year cumulative survival (73.0% vs 47.9%) (P = 0.009), 3-year local recurrence rate (29.1% vs 51.5%) (P = 0.011), and 5-year distant intrahepatic recurrence rate (52.9% vs 62.8%) (P = 0.054) compared to patients with a larger tumor. CONCLUSION: The 5-year survival rate of patients with single hepatocellular carcinoma < 2 cm undergoing ethanol injection is excellent and comparable to that achieved using radiofrequency ablation.

  11. Application of a model for delivering occupational safety and health to smaller businesses: Case studies from the US.

    Science.gov (United States)

    Cunningham, Thomas R; Sinclair, Raymond

    2015-01-01

    Smaller firms are the majority in every industry in the US, and they endure a greater burden of occupational injuries, illnesses, and fatalities than larger firms. Smaller firms often lack the necessary resources for effective occupational safety and health activities, and many require external assistance with safety and health programming. Based on previous work by researchers in Europe and New Zealand, NIOSH researchers developed for occupational safety and health intervention in small businesses. This model was evaluated with several intermediary organizations. Four case studies which describe efforts to reach small businesses with occupational safety and health assistance include the following: trenching safety training for construction, basic compliance and hazard recognition for general industry, expanded safety and health training for restaurants, and fall prevention and respirator training for boat repair contractors. Successful efforts included participation by the initiator among the intermediaries' planning activities, alignment of small business needs with intermediary offerings, continued monitoring of intermediary activities by the initiator, and strong leadership for occupational safety and health among intermediaries. Common challenges were a lack of resources among intermediaries, lack of opportunities for in-person meetings between intermediaries and the initiator, and balancing the exchanges in the initiator-intermediary-small business relationships. The model offers some encouragement that initiator organizations can contribute to sustainable OSH assistance for small firms, but they must depend on intermediaries who have compatible interests in smaller businesses and they must work to understand the small business social system.

  12. Study on the measure to improve the arc stabilization in smaller current welding for the variable polarity GTAW power source

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The variable polarity power source which incorporates a constant current power and a secondary inverter does not need special apparatus for stabilizing arc. The pulse for stabilizing arc is created by the circuit structure itself. The paper analyzes the principle of acquiring the pulse, provides the better method to improve the arc stabilization under smaller welding current. Test shows the arc is highly stable , and the process has no high-frequency electromagnetic interference, which is suitable for automatic welding case.

  13. Transforming a large-class lecture course to a smaller-group interactive course.

    Science.gov (United States)

    Persky, Adam M; Pollack, Gary M

    2010-11-10

    To transition a large pharmacokinetics course that was delivered using a traditional lecture format into a smaller-group course with a discussion format. An e-book and Web-based multimedia learning modules were utilized to facilitate students' independent learning which allowed the number of classes they were required to attend to be reduced from 3 to 1 per week. Students were assigned randomly to 1 of 3 weekly class sessions. The majority of lecture time was replaced with active-learning activities including discussion, problem solving, and case studies to encourage higher-order learning. Changes in course delivery were assessed over a 4-year period by comparing students' grades and satisfaction ratings on course evaluations. Although student satisfaction with the course did not improve significantly, students preferred the smaller-group setting to a large lecture-based class. The resources and activities designed to shift responsibility for learning to the students did not affect examination grades even though a larger portion of examination questions focused on higher orders of learning (eg, application) in the smaller-group format. Transitioning to a smaller-group discussion format is possible in a pharmacokinetics course by increasing student accountability for acquiring factual content outside of the classroom. Students favored the smaller-class format over a large lecture-based class.

  14. The Health Show

    OpenAIRE

    Swann, David

    2011-01-01

    Dr David Swann interviewed on The Health Show, Series 1, Episode 5, 2011 for BBC World about the award-winning 21st Century Nursing Bag. BBC World News reaches 241million people every week, available in 296 million homes, 1.8 million hotel rooms and has the highest average viewership on a weekday of any international news channel. The Health Show is a new 26-part series for BBC World News covering the most important news stories from around the world.

  15. Fewer but not smaller schools in declining fish and krill populations.

    Science.gov (United States)

    Brierley, Andrew S; Cox, Martin J

    2015-01-05

    Many pelagic species (species that live in the water column), including herring and krill, aggregate to form schools, shoals, or swarms (hereafter simply "schools," although the words are not synonyms). Schools provide benefits to individual members, including locomotory economy and protection from predators that prey on individuals, but paradoxically make schooling species energetically viable and commercially attractive targets for predators of groups and for fishers. Large schools are easier to find and yield greater prey/catch than small schools, and there is a requirement from fields as diverse as theoretical ecology and fisheries management to understand whether and how aggregation sizes change with changing population size. We collated data from vertical echosounder surveys of taxonomically diverse pelagic stocks from geographically diverse ecosystems. The data contain common significant positive linear stock-biomass to school-number relationships. They show that the numbers of schools in the stocks change with changing stock biomass and suggest that the distributions of school sizes do not change with stock biomass. New data that we collected using a multibeam sonar, which can image entire schools, contained the same stock-biomass to school-number relationship and confirm that the distribution of school sizes is not related to changing stock size: put simply, as stocks decline, individuals are distributed among fewer schools, not smaller schools. Since school characteristics affect catchability (the ease or difficulty with which fishers can capture target species) and availability of prey to predators, our findings have commercial and ecological implications, particularly within the aspirational framework of ecosystem-based management of marine systems.

  16. Simulating the magnetized liner inertial fusion plasma confinement with smaller-scale experiments [Simulating the MagLIF plasma confinement with smaller-scale experiments

    Energy Technology Data Exchange (ETDEWEB)

    Ryutov, D. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Cuneo, M. E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Herrmann, M. C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sinars, D. B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Slutz, S. A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2012-06-20

    The recently proposed magnetized liner inertial fusion approach to a Z-pinch driven fusion [Slutz et al., Phys. Plasmas17, 056303 (2010)] is based on the use of an axial magnetic field to provide plasma thermal insulation from the walls of the imploding liner. The characteristic plasma transport regimes in the proposed approach cover parameter domains that have not been studied yet in either magnetic confinement or inertial confinement experiments. In this article, an analysis is presented of the scalability of the key physical processes that determine the plasma confinement. The dimensionless scaling parameters are identified and conclusion is drawn that the plasma behavior in scaled-down experiments can correctly represent the full-scale plasma, provided these parameters are approximately the same in two systems. Furthermore, this observation is important in that smaller-scale experiments typically have better diagnostic access and more experiments per year are possible.

  17. Risk Aversion in Game Shows

    DEFF Research Database (Denmark)

    2008-01-01

    We review the use of behavior from television game shows to infer risk attitudes. These shows provide evidence when contestants are making decisions over very large stakes, and in a replicated, structured way. Inferences are generally confounded by the subjective assessment of skill in some games......, and the dynamic nature of the task in most games. We consider the game shows Card Sharks, Jeopardy!, Lingo, and finally Deal Or No Deal. We provide a detailed case study of the analyses of Deal Or No Deal, since it is suitable for inference about risk attitudes and has attracted considerable attention....

  18. Generalized BPS magnetic monopoles

    Science.gov (United States)

    Casana, R.; Ferreira, M. M., Jr.; da Hora, E.

    2012-10-01

    We show the existence of Bogomol’nyi-Prasad-Sommerfield (BPS) magnetic monopoles in a generalized Yang-Mills-Higgs model which is controlled by two positive functions, g(ϕaϕa) and f(ϕaϕa). This effective model, in principle, would describe the dynamics of the nonabelian fields in a chromoelectric media. We check the consistency of our generalized construction by analyzing an explicit case ruled by a parameter β. We also use the well-known spherically symmetric Ansatz to attain the corresponding self-dual equations describing the topological solutions. The overall conclusion is that the new solutions behave around the canonical one, with smaller or greater characteristic length depending on the values of β.

  19. A Fashion Show

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    <正>Story: The yearly fashion show day.The children take turns to walk on the stage and show the class their favorite clothes.Now it’s Joe’s and Phoebe’s turn.Joe walks on the stage and says,“My shorts are blue.Do you like my blue shorts?”On the other side of the stage, Phoebe is wearing her favorite pink skirt.“My skirt is pink.Do you like my pink skirt?”asks

  20. Opportunities for smaller engineering companies despite globalization. Chancen kleiner Ingenieurbueros trotz Globalisierung

    Energy Technology Data Exchange (ETDEWEB)

    Lorentzen, P. (IPL Ingenieurbuero Peter Lorentzen, Frankfurt am Main (Germany))

    1999-06-01

    The trend to size is escalating into gigantism. The biggest in the branch merge to become the oversized. In view of this situation, the question which arises is what are the survival chances of the smaller players Will they all drop out of the running The answer to this question does not only concern the future order books of smaller companies, but in conjunction therewith and predominately the social security of employees, type and scope of assignments as well as the competitive situation and the consequences of all these on remuneration. (orig.)

  1. Diagnostic sensitivity of imaging modalities for hepatocellular carcinoma smaller than 2 cm

    Institute of Scientific and Technical Information of China (English)

    Keiji; Mita; Soo; Ryang; Kim; Masatoshi; Kudo; Susumu; Imoto; Taisuke; Nakajima; Kenji; Ando; Katsumi; Fukuda; Toshiyuki; Matsuoka; Yoko; Maekawa; Yoshitake; Hayashi

    2010-01-01

    AIM:To compare the imaging results with histology and to evaluate the diagnostic sensitivity of imaging modalities for hepatocellular carcinoma(HCC)smaller than 2 cm.METHODS:Nodules smaller than 2 cm(n=34)revealed by ultrasonography(US)in 29 patients with liver cirrhosis were analyzed.Histological diagnosis of HCC was performed by ultrasonographic guidance:moderately-differentiated HCC(n=24);well-differentiated HCC(n=10).The patterns disclosed by the four imaging modalities defined the conclusive diagnosis ...

  2. On not showing scalps

    DEFF Research Database (Denmark)

    Marselis, Randi Lorenz

    2016-01-01

    proposed by Janet Marstine, the editor of the Routledge Companion to Museum Ethics, I show how the museum succeeded in engaging users in questions of museum ethics. However, this specific debate on human remains in museums developed into an encounter between a global, museological discourse...

  3. Violence and TV Shows

    OpenAIRE

    ÖZTÜRK, Yrd. Doç. Dr. Şinasi

    2008-01-01

    This study aims to discuss theories on theviolent effects of TV shows on viewers, especiallyon children. Therefore, this study includes a briefdiscussion of definitions of violence, discussionof violence theories, main results of researcheson televised violence, measuring TV violence,perception of televised violence, individualdifferences and reactions to TV violence,aggressiveness and preferences for TV violence.

  4. Honored Teacher Shows Commitment.

    Science.gov (United States)

    Ratte, Kathy

    1987-01-01

    Part of the acceptance speech of the 1985 National Council for the Social Studies Teacher of the Year, this article describes the censorship experience of this honored social studies teacher. The incident involved the showing of a videotape version of the feature film entitled "The Seduction of Joe Tynan." (JDH)

  5. A Visionary Show

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Seduction. Distinction. Relax. Pulsation. These are the "style universes" on display at Première Vision, heralded as "The World’s Premiere Fabric Show." Started more than 35 years ago by 15 French weavers, Première Vision has expanded beyond its

  6. Honored Teacher Shows Commitment.

    Science.gov (United States)

    Ratte, Kathy

    1987-01-01

    Part of the acceptance speech of the 1985 National Council for the Social Studies Teacher of the Year, this article describes the censorship experience of this honored social studies teacher. The incident involved the showing of a videotape version of the feature film entitled "The Seduction of Joe Tynan." (JDH)

  7. Measurement of testicular volume in smaller testes: how accurate is the conventional orchidometer?

    Science.gov (United States)

    Lin, Chih-Chieh; Huang, William J S; Chen, Kuang-Kuo

    2009-01-01

    The aim of this study was to evaluate the accuracy of different methods, including the Seager orchidometer (SO) and ultrasonography (US), for assessing testicular volume of smaller testes (testes volume less than 18 mL). Moreover, the equations used for the calculations--the Hansen formula (length [L] x width [W](2) x 0.52, equation A), the prolate ellipsoid formula (L x W x height [H] x 0.52, equation B), and the Lambert equation (L x W x H x 0.71, equation C)--were also examined and compared with the gold standard testicular volume obtained by water displacement (Archimedes principle). In this study, 30 testes from 15 men, mean age 75.3 (+/-8.3) years, were included. They all had advanced prostate cancer and were admitted for orchiectomy. Before the procedure, all the testes were assessed using SO and US. The dimensions were then input into each equation to obtain the volume estimates. The testicular volume by water displacement was 8.1 +/- 3.5 mL. Correlation coefficients (R(2)) of the 2 different methods (SO, US) to the gold standard were 0.70 and 0.85, respectively. The calculated testicular volumes were 9.2 +/- 3.9 mL (measured by SO, equation A), 11.9 +/- 5.2 mL (measured by SO, equation C), 7.3 +/- 4.2 mL (measured by US, equation A), 6.5 +/- 3.3 mL (measured by US, equation B) and 8.9 +/- 4.5 mL (measured by US, equation C). Only the mean size measured by US and volume calculated with the Hansen equation (equation A) and the mean size measured by US and volume calculated with the Lambert equation (equation C) showed no significant differences when compared with the volumes estimated by water displacement (mean difference 0.81 mL, P = .053, and 0.81 mL, P = .056, respectively). Based on our measurements, we categorized testicular volume by different cutoff values (7.0 mL, 7.5 mL, 8.0 mL, and 8.5 mL) to calculate a new constant for use in the Hansen equation. The new constant was 0.59. We then reexamined the equations using the new 0.59 constant, and found

  8. Shanghai Shows Its Heart

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The city known as China’s economic powerhouse showed a more caring face as host of the Special Olympic Games Between October 2 and 11,the Special Olympics Summer Games were hosted in Shanghai,the first time the 40-year-old athletic com- petition for people with intellectual disabilities came to a developing country. This Special Olympics was also larger than all previous games in temps of the number of athletes.

  9. Smaller hippocampal volume as a vulnerability factor for the persistence of post-traumatic stress disorder

    NARCIS (Netherlands)

    van Rooij, S J H; Kennis, M; Sjouwerman, R; van den Heuvel, M P; Kahn, R S; Geuze, E

    2015-01-01

    BACKGROUND: Smaller hippocampal volume has often been observed in patients with post-traumatic stress disorder (PTSD). However, there is no consensus whether this is a result of stress/trauma exposure, or constitutes a vulnerability factor for the development of PTSD. Second, it is unclear whether h

  10. Smaller hippocampal volume as a vulnerability factor for the persistence of post-traumatic stress disorder

    NARCIS (Netherlands)

    Van Rooij, S. J H; Kennis, M.; Sjouwerman, R.; Van Den Heuvel, M. P.|info:eu-repo/dai/nl/304820466; Kahn, R. S.|info:eu-repo/dai/nl/073778532; Geuze, E.

    2015-01-01

    Background Smaller hippocampal volume has often been observed in patients with post-traumatic stress disorder (PTSD). However, there is no consensus whether this is a result of stress/trauma exposure, or constitutes a vulnerability factor for the development of PTSD. Second, it is unclear whether hi

  11. 40 CFR 246.200-2 - Recommended procedures: High-grade paper recovery from smaller offices.

    Science.gov (United States)

    2010-07-01

    ... offices. The recovery of high-grade paper generated by office facilities of less than 100 office workers... paper recovery from smaller offices. 246.200-2 Section 246.200-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES...

  12. Trends and patterns in contemporary management in smaller companies: The Danish perspective

    DEFF Research Database (Denmark)

    Ulhøi, John Parm; Madsen, Henning

    2001-01-01

    This paper reports empirical findings from a recent survey of Danish managers with a special focus on managers from smaller companies. The survey has been initiated in Denmark and it is called the 'Danish Management Barometer'. The project is a joint research program between the Aarhus School...

  13. Diffusion Approximation of a Multitype Re-entrant Line under Smaller-buffer-first-served Policy

    Institute of Scientific and Technical Information of China (English)

    Jian Kui YANG

    2011-01-01

    This paper studies a multitype re-entrant line under smaller-buffer-first-served policy,which is an extension of first-buffer-first-served re-entrant line.We prove a heavy traffic limit theorem.The key to the proof is to prove the uniform convergence of the corresponding critical fluid model.

  14. The role of interpretation in the internationalization of smaller brazilian firms

    NARCIS (Netherlands)

    R. Seifert; J. Child (John); S.B. Rodrigues (Suzana Braga)

    2012-01-01

    textabstractAbstract This study considers how decision-makers in smaller firms interpret the means and conditions of internationalization, and how different modes of interpretation are likely to inform action choices in this process. Drawing on 58 qualitative interviews with the leaders of Brazilian

  15. Smaller muscle ATP reduction in women than in men by repeated bouts of sprint exercise.

    Science.gov (United States)

    Esbjörnsson-Liljedahl, Mona; Bodin, Kristina; Jansson, Eva

    2002-09-01

    It was hypothesized that the reduction of high-energy phosphates in muscle after repeated sprints is smaller in women than in men. Fifteen healthy and physically active women and men with an average age of 25 yr (range of 19-42 yr) performed three 30-s cycle sprints (Wingate test) with 20 min of rest between sprints. Repeated blood and muscle samples were obtained. Freeze-dried pooled muscle fibers of types I and II were analyzed for high-energy phosphates and their breakdown products and for glycogen. Accumulation of plasma ATP breakdown products, plasma catecholamines, and blood lactate, as well as glycogen reduction in type I fibers, was all lower in women than in men during sprint exercise. Repeated sprints induced smaller reduction of ATP and smaller accumulation of IMP and inosine in women than in men in type II muscle fibers, with no gender differences in changes of ATP and its breakdown products during the bouts of exercise themselves. This indicates that the smaller ATP reduction in women than in men during repeated sprints was created during recovery periods between the sprint exercises and that women possess a faster recovery of ATP via reamination of IMP during these recovery periods.

  16. 75 FR 37779 - Office of Elementary and Secondary Education; Smaller Learning Communities Program; Notice...

    Science.gov (United States)

    2010-06-30

    ...On June 23, 2010, we published in the Federal Register (75 FR 35894) a notice inviting applications for new awards using fiscal year (FY) 2009 funds for the Smaller Learning Communities Program. There are errors in two of the dates in that notice. We are correcting those dates in this...

  17. Warming temperatures and smaller body sizes: synchronous changes in grwoth of North Sea fishes

    NARCIS (Netherlands)

    Baudron, A.; Needle, C.; Rijnsdorp, A.D.; Marshall, C.T.

    2014-01-01

    Decreasing body size has been proposed as a universal response to increasing temperatures. The physiology behind the response is well established for ectotherms inhabiting aquatic environments: as higher temperatures decrease the aerobic capacity, individuals with smaller body sizes have a reduced r

  18. Casimir experiments showing saturation effects

    CERN Document Server

    Sernelius, Bo E

    2009-01-01

    We address several different Casimir experiments where theory and experiment disagree. First out is the classical Casimir force measurement between two metal half spaces; here both in the form of the torsion pendulum experiment by Lamoreaux and in the form of the Casimir pressure measurement between a gold sphere and a gold plate as performed by Decca et al.; theory predicts a large negative thermal correction, absent in the high precision experiments. The third experiment is the measurement of the Casimir force between a metal plate and a laser irradiated semiconductor membrane as performed by Chen et al.; the change in force with laser intensity is larger than predicted by theory. The fourth experiment is the measurement of the Casimir force between an atom and a wall in the form of the measurement by Obrecht et al. of the change in oscillation frequency of a 87 Rb Bose-Einstein condensate trapped to a fused silica wall; the change is smaller than predicted by theory. We show that saturation effects can exp...

  19. HIV Distal Neuropathic Pain Is Associated with Smaller Ventral Posterior Cingulate Cortex.

    Science.gov (United States)

    Keltner, John R; Connolly, Colm G; Vaida, Florin; Jenkinson, Mark; Fennema-Notestine, Christine; Archibald, Sarah; Akkari, Cherine; Schlein, Alexandra; Lee, Jisu; Wang, Dongzhe; Kim, Sung; Li, Han; Rennels, Austin; Miller, David J; Kesidis, George; Franklin, Donald R; Sanders, Chelsea; Corkran, Stephanie; Grant, Igor; Brown, Gregory G; Atkinson, J Hampton; Ellis, Ronald J

    2017-03-01

    . Despite modern antiretroviral therapy, HIV-associated neuropathy is one of the most prevalent, disabling and treatment-resistant complications of HIV disease. The presence and intensity of distal neuropathic pain is not fully explained by the degree of peripheral nerve damage. A better understanding of brain structure in HIV distal neuropathic pain may help explain why some patients with HIV neuropathy report pain while the majority does not. Previously, we reported that more intense distal neuropathic pain was associated with smaller total cerebral cortical gray matter volumes. The objective of this study was to determine which parts of the cortex are smaller. . HIV positive individuals with and without distal neuropathic pain enrolled in the multisite (N = 233) CNS HIV Antiretroviral Treatment Effects (CHARTER) study underwent structural brain magnetic resonance imaging. Voxel-based morphometry was used to investigate regional brain volumes in these structural brain images. . Left ventral posterior cingulate cortex was smaller for HIV positive individuals with versus without distal neuropathic pain (peak P  = 0.017; peak t = 5.15; MNI coordinates x = -6, y = -54, z = 20). Regional brain volumes within cortical gray matter structures typically associated with pain processing were also smaller for HIV positive individuals having higher intensity ratings of distal neuropathic pain. . The posterior cingulate is thought to be involved in inhibiting the perception of painful stimuli. Mechanistically a smaller posterior cingulate cortex structure may be related to reduced anti-nociception contributing to increased distal neuropathic pain.

  20. Not a "reality" show.

    Science.gov (United States)

    Wrong, Terence; Baumgart, Erica

    2013-01-01

    The authors of the preceding articles raise legitimate questions about patient and staff rights and the unintended consequences of allowing ABC News to film inside teaching hospitals. We explain why we regard their fears as baseless and not supported by what we heard from individuals portrayed in the filming, our decade-long experience making medical documentaries, and the full un-aired context of the scenes shown in the broadcast. The authors don't and can't know what conversations we had, what documents we reviewed, and what protections we put in place in each televised scene. Finally, we hope to correct several misleading examples cited by the authors as well as their offhand mischaracterization of our program as a "reality" show.

  1. Dysfunctional lipoproteins from young smokers exacerbate cellular senescence and atherogenesis with smaller particle size and severe oxidation and glycation.

    Science.gov (United States)

    Park, Ki-Hoon; Shin, Dong-Gu; Cho, Kyung-Hyun

    2014-07-01

    Until now, there has been limited information on the effects of smoking on atherogenesis and senescence in the context of lipoprotein parameters, particularly in young smokers who have smoked fewer than 10 cigarettes per day for 3 years. In this study, lipoprotein profiles and functions were compared between smoker (n = 21) and control groups (n = 20). In the smoking group, ferric ion reduction abilities of serum and high-density lipoprotein (HDL) fractions were significantly reduced, and low-density lipoprotein (LDL) was severely oxidized. All lipoprotein particles from the smoker group showed higher advanced glycated end products with more triglyceride (TG) content compared with the control group. Lipoproteins from smokers showed faster agarose gel electromobility as well as greater smear band intensity in SDS-PAGE due to oxidation and glycation. LDL from smokers was more sensitive to oxidation and promoted foam cell forma-tion in macrophages. Gel filtration column chromatography revealed that the protein and cholesterol peaks of VLDL and LDL were elevated in the smoker group, whereas those of HDL were reduced. Human dermal fibroblast cells from the smoker group showed severe senescence following treatment with HDL2 and HDL3. Although HDL from young smokers showed impaired antioxidant ability, smaller particle size, and increased TG content, cholesteryl ester transfer protein activities were greatly enhanced in the serum and HDL fractions of the smoker group. In conclusion, smoking can cause production of dysfunctional lipoproteins having a smaller particle size that exacerbate senescence and atherogenic progress due to oxidation and glycation.

  2. Showing Value (Editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2009-06-01

    Full Text Available When Su Cleyle and I first decided to start Evidence Based Library and Information Practice, one of the things we agreed upon immediately was that the journal be open access. We knew that a major obstacle to librarians using the research literature was that they did not have access to the research literature. Although Su and I are both academic librarians who can access a wide variety of library and information literature from our institutions, we belong to a profession where not everyone has equal access to the research in our field. Without such access to our own body of literature, how can we ever hope for practitioners to use research evidence in their decision making? It would have been contradictory to the principles of evidence based library and information practice to do otherwise.One of the specific groups we thought could use such an open access venue for discovering research literature was school librarians. School librarians are often isolated and lacking access to the research literature that may help them prove to stakeholders the importance of their libraries and their role within schools. Certainly, school libraries have been in decline and the use of evidence to show value is needed. As Ken Haycock noted in his 2003 report, The Crisis in Canada’s School Libraries: The Case for Reform and Reinvestment, “Across the country, teacher-librarians are losing their jobs or being reassigned. Collections are becoming depleted owing to budget cuts. Some principals believe that in the age of the Internet and the classroom workstation, the school library is an artifact” (9. Within this context, school librarians are looking to our research literature for evidence of the impact that school library programs have on learning outcomes and student success. They are integrating that evidence into their practice, and reflecting upon what can be improved locally. They are focusing on students and showing the impact of school libraries and

  3. Are There Smaller Leverage Effects in Less-Developed Markets? Evidence from an Oil Exporting Country

    Directory of Open Access Journals (Sweden)

    Mosayeb Phalavani

    2010-01-01

    Full Text Available Problem statement: This study uses daily data from the Tehran Stock Market (TSM to illustrate the nature of stock market volatility in an undeveloped and young stock market. Although most studies suggest that a negative shock to stock prices will generate more volatility than a positive shock of equal magnitude but there is no evidence of asymmetric effect in TSM. Determine the nature of stock market volatility in an oil exporting country. Approach: Trading in Tehran Stock Market (TSM is based on orders sent by the brokers. The data consist of 2375 daily observations of the closing value of the Tehran stock market from 3/30/1998 to 5/04/2007. Our empirical finding shows that the unconditional variance is 0.18 but visual inspections of the time series suggests that volatility of the stock return rate displays the clustering phenomenon associated with GARCH processes. Results: The estimation and test results for all models suggest that the leverage effect term, γ, is not significant at 5% level. Although, in Asym. CARCH model based on normal distribution for errors, the estimated coefficient on the asymmetry term is -0.066 with a z-statistics of -1.749 recognized as significant at 10% level, but it has the wrong sign. It seems that good news and bad news has the same effect on stock prices in TSM, a result that is contradictory to other studies for developed countries. Conclusion: The estimated models containing TARCH, EGARCH, asymmetric CARCH and PARCH with different assumptions on error distributions suggest no strong and significant asymmetric effect. There are some reasons for this finding: (1 In Iran with Islamic laws, debt contracts are illegal or at least not enforced and Iranian firms do not have any financial leverage. As a result, we would expect to find smaller leverage effects in volatility in Iran than in the United States, for example. In deed the institutional differences with western financial markets manifest themselves in

  4. Public medical shows.

    Science.gov (United States)

    Walusinski, Olivier

    2014-01-01

    In the second half of the 19th century, Jean-Martin Charcot (1825-1893) became famous for the quality of his teaching and his innovative neurological discoveries, bringing many French and foreign students to Paris. A hunger for recognition, together with progressive and anticlerical ideals, led Charcot to invite writers, journalists, and politicians to his lessons, during which he presented the results of his work on hysteria. These events became public performances, for which physicians and patients were transformed into actors. Major newspapers ran accounts of these consultations, more like theatrical shows in some respects. The resultant enthusiasm prompted other physicians in Paris and throughout France to try and imitate them. We will compare the form and substance of Charcot's lessons with those given by Jules-Bernard Luys (1828-1897), Victor Dumontpallier (1826-1899), Ambroise-Auguste Liébault (1823-1904), Hippolyte Bernheim (1840-1919), Joseph Grasset (1849-1918), and Albert Pitres (1848-1928). We will also note their impact on contemporary cinema and theatre.

  5. Longer leukocyte telomere length is associated with smaller hippocampal volume among non-demented APOE ε3/ε3 subjects.

    Directory of Open Access Journals (Sweden)

    Mikael Wikgren

    Full Text Available Telomere length shortens with cellular division, and leukocyte telomere length is used as a marker for systemic telomere length. The hippocampus hosts adult neurogenesis and is an important structure for episodic memory, and carriers of the apolipoprotein E ε4 allele exhibit higher hippocampal atrophy rates and differing telomere dynamics compared with non-carriers. The authors investigated whether leukocyte telomere length was associated with hippocampal volume in 57 cognitively intact subjects (29 ε3/ε3 carriers; 28 ε4 carriers aged 49-79 yr. Leukocyte telomere length correlated inversely with left (r(s = -0.465; p = 0.011, right (r(s = -0.414; p = 0.025, and total hippocampus volume (r(s = -0.519; p = 0.004 among APOE ε3/ε3 carriers, but not among ε4 carriers. However, the ε4 carriers fit with the general correlation pattern exhibited by the ε3/ε3 carriers, as ε4 carriers on average had longer telomeres and smaller hippocampi compared with ε3/ε3 carriers. The relationship observed can be interpreted as long telomeres representing a history of relatively low cellular proliferation, reflected in smaller hippocampal volumes. The results support the potential of leukocyte telomere length being used as a biomarker for tapping functional and structural processes of the aging brain.

  6. The Great Cometary Show

    Science.gov (United States)

    2007-01-01

    its high spatial and spectral resolution, it was possible to zoom into the very heart of this very massive star. In this innermost region, the observations are dominated by the extremely dense stellar wind that totally obscures the underlying central star. The AMBER observations show that this dense stellar wind is not spherically symmetric, but exhibits a clearly elongated structure. Overall, the AMBER observations confirm that the extremely high mass loss of Eta Carinae's massive central star is non-spherical and much stronger along the poles than in the equatorial plane. This is in agreement with theoretical models that predict such an enhanced polar mass-loss in the case of rapidly rotating stars. ESO PR Photo 06c/07 ESO PR Photo 06c/07 RS Ophiuchi in Outburst Several papers from this special feature focus on the later stages in a star's life. One looks at the binary system Gamma 2 Velorum, which contains the closest example of a star known as a Wolf-Rayet. A single AMBER observation allowed the astronomers to separate the spectra of the two components, offering new insights in the modeling of Wolf-Rayet stars, but made it also possible to measure the separation between the two stars. This led to a new determination of the distance of the system, showing that previous estimates were incorrect. The observations also revealed information on the region where the winds from the two stars collide. The famous binary system RS Ophiuchi, an example of a recurrent nova, was observed just 5 days after it was discovered to be in outburst on 12 February 2006, an event that has been expected for 21 years. AMBER was able to detect the extension of the expanding nova emission. These observations show a complex geometry and kinematics, far from the simple interpretation of a spherical fireball in extension. AMBER has detected a high velocity jet probably perpendicular to the orbital plane of the binary system, and allowed a precise and careful study of the wind and the shockwave

  7. Origin of the smaller conductances of Rh, Pb, and Co atomic junctions in hydrogen environment

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xue; Chen, Mingyan; Ye, Xiang; Xie, Yi-qun, E-mail: yqxie@shnu.edu.cn [Department of Physics, Shanghai Normal University, 100 Guilin Road, Shanghai 200232 (China); Ke, San-huang, E-mail: shke@tongji.edu.cn [MOE Key Laboratory of Advanced Microstructured Materials, School of Physics Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092 (China)

    2015-02-14

    We study theoretically the structural and electronic origins of the smaller conductances (one conductance quantum, G{sub 0}, and smaller) of Rh, Pb, and Co metal atomic junctions (MAJs) in a hydrogen environment, as were measured in recent experiments. For the Rh MAJs, the 1G{sub 0} conductance is attributed to a stable contact bridged by a single hydrogen molecule whose antibonding state provides a single transport channel. For the Pb and Co MAJs the 1G{sub 0} conductance is, however, ascribed to a linear atomic chain adsorbing two dissociated H atoms, which largely reduces the density of states at the Fermi energy with respect to the pure ones. On the other hand, the small conductances of 0.3G{sub 0} (Rh) and 0.2G{sub 0} (Co) are due to H-decorated atomic chains connected to electrodes by a H atom.

  8. Smaller pupil size and better proofreading performance with positive than with negative polarity displays.

    Science.gov (United States)

    Piepenbrock, Cosima; Mayr, Susanne; Buchner, Axel

    2014-01-01

    The 'positive polarity advantage' describes the fact that reading performance is better for dark text on light background (positive polarity) than for light text on dark background (negative polarity). We investigated the underlying mechanism by assessing pupil size and proofreading performance when reading positive and negative polarity texts. In particular, we tested the display luminance hypothesis which postulates that the typically greater brightness of positive compared to negative polarity displays leads to smaller pupil sizes and, hence, a sharper retinal image and better perception of detail. Indeed, pupil sizes were smaller and proofreading performance was better with positive than with negative polarity displays. The results are compatible with the hypothesis that the positive polarity advantage is an effect of display luminance. Limitations of the study are being discussed.

  9. How food marketers can sell smaller portions: Consumer insights and product innovation.

    Science.gov (United States)

    Riis, J; Fisher, J O; Rowe, S

    2016-08-01

    Food portion size has been shown to be an important driver of energy intake. Despite the well acknowledged role of portion control in weight management, large portion sizes remain ubiquitous in the marketplace. Moving consumers towards consumption of smaller portion sizes will require changes in consumer behavior as well as changes in products available to consumers in a variety of settings. This special supplement presents cutting edge research aimed at understanding consumer behavior around portion size and innovations in product design that may promote the selection and consumption of smaller portion sizes. We identify further research that will be needed to translate basic behavioral findings into real world settings and to viable product development.

  10. Leaning to the left makes the Eiffel Tower seem smaller: posture-modulated estimation.

    Science.gov (United States)

    Eerland, Anita; Guadalupe, Tulio M; Zwaan, Rolf A

    2011-12-01

    In two experiments, we investigated whether body posture influences people's estimation of quantities. According to the mental-number-line theory, people mentally represent numbers along a line with smaller numbers on the left and larger numbers on the right. We hypothesized that surreptitiously making people lean to the right or to the left would affect their quantitative estimates. Participants answered estimation questions while standing on a Wii Balance Board. Posture was manipulated within subjects so that participants answered some questions while they leaned slightly to the left, some questions while they leaned slightly to the right, and some questions while they stood upright. Crucially, participants were not aware of this manipulation. Estimates were significantly smaller when participants leaned to the left than when they leaned to the right.

  11. Participation of smaller size renewable generation in the electricity market trade in UK: Analyses and approaches

    DEFF Research Database (Denmark)

    Romanovsky, G.; Xydis, G.; Mutale, J.

    2011-01-01

    While there are presently different options for renewable and distributed generation (RES/DG) to participate in the UK electricity market, none of the market options is specifically tailored for such types of generation and in particular, the smaller (up to 5 MW) RES/DG. This is because the UK has...... a number of specific historical, technical and economic reasons that significantly influenced the ability of the smaller size RES/DG to participate in the electricity market and in provision of balancing services in accordance with the UK National Grid requirements. This paper discusses some perspectives...... and approaches aiming to help stand alone small size and clusters of RES and DG units to participate in the UK electricity market drawing on relevant experience from Denmark....

  12. Innovation centres as growth points for smaller towns and rural areas

    Directory of Open Access Journals (Sweden)

    Belova A. V.

    2012-01-01

    Full Text Available This article addresses the role of innovative centres in the development of surrounding areas beyond large cities. At the same time, the innovative development of rural areas should be of a composite nature; municipality development strategies take innovations into account. International practices serve as a an argument in favour of establishing innovative centres in smaller and medium-sized towns in order to facilitate the socioeconomic development of the territory and surrounding rural areas. Science parks created in smaller towns give a boost to socioeconomic development. The authors analyse the case of the science park in the town of Gusev in the Kaliningrad region and emphasise the role of development and adoption of legal acts at regional and municipal levels, for example, the law «On the production policy of the Kaliningrad region».

  13. Plant Proteins Are Smaller Because They Are Encoded by Fewer Exons than Animal Proteins

    Directory of Open Access Journals (Sweden)

    Obed Ramírez-Sánchez

    2016-12-01

    Full Text Available Protein size is an important biochemical feature since longer proteins can harbor more domains and therefore can display more biological functionalities than shorter proteins. We found remarkable differences in protein length, exon structure, and domain count among different phylogenetic lineages. While eukaryotic proteins have an average size of 472 amino acid residues (aa, average protein sizes in plant genomes are smaller than those of animals and fungi. Proteins unique to plants are ∼81 aa shorter than plant proteins conserved among other eukaryotic lineages. The smaller average size of plant proteins could neither be explained by endosymbiosis nor subcellular compartmentation nor exon size, but rather due to exon number. Metazoan proteins are encoded on average by ∼10 exons of small size [∼176 nucleotides (nt]. Streptophyta have on average only ∼5.7 exons of medium size (∼230 nt. Multicellular species code for large proteins by increasing the exon number, while most unicellular organisms employ rather larger exons (>400 nt. Among subcellular compartments, membrane proteins are the largest (∼520 aa, whereas the smallest proteins correspond to the gene ontology group of ribosome (∼240 aa. Plant genes are encoded by half the number of exons and also contain fewer domains than animal proteins on average. Interestingly, endosymbiotic proteins that migrated to the plant nucleus became larger than their cyanobacterial orthologs. We thus conclude that plants have proteins larger than bacteria but smaller than animals or fungi. Compared to the average of eukaryotic species, plants have ∼34% more but ∼20% smaller proteins. This suggests that photosynthetic organisms are unique and deserve therefore special attention with regard to the evolutionary forces acting on their genomes and proteomes.

  14. Spending Power on the rise in China’s Smaller Cities

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    China’s big spenders now far-flung by Yu Nan WIDELY recognized as one of the most beautiful cities in China,the coastal port of Dalian is a perfect example of a lowertier city becoming a growth hub for multinationals, owing to stronger purchasing power. That trend inspired Boston Consulting Group(BCG) to release a report,advising businessmen to look beyond the familiar mega-cities to the fast-growing smaller

  15. The Mass-Radius Relation Between 60 Exoplanets Smaller than 4 Earth Radii

    CERN Document Server

    Weiss, Lauren M

    2013-01-01

    We study the masses and radii of 60 exoplanets smaller than 4 Earth radii with orbital periods shorter than 100 days. We find a nearly linear mass-radius relation: M/M_E= 3.17 (R/R_E)^0.87, which is a shallower power-law index than in many previous mass-radius relations. The RMS of planet masses to this fit is 3.9 Earth masses, and our best fit has reduced chi squared = 3.1, indicating a diversity in planet compositions below 4 Earth radii. Fitting density vs. radius with a polynomial, we find planet density = 11.50 - 5.97 (R/R_E) + 0.84 (R/R_E)^2. The mass-radius and mass-density relations reflect that planet density decreases as radius increases, indicating that larger exoplanets have a significant fraction of volatiles by volume (such as H/He envelopes). Exoplanets have densities comparable to that of Earth at R = 1.5 R_E, indicating likely rocky compositions among planets smaller than 1.5 Earth radii. The scaling of the mass-radius relationship for exoplanets smaller than 1.5 Earth radii is not well-const...

  16. PLC/PC monitoring, control systems a boon for smaller NGL plants. [Programmable Logic Controllers and Personal Computers

    Energy Technology Data Exchange (ETDEWEB)

    Gill, M.R.; Sisk, L.B.; Warren, W.F. (Texaco Inc., Houston, TX (United States)); Simpson, T.W. (Texaco U.S.A., Velma, OK (United States))

    1993-11-01

    Experience of two plants operated by Texaco U.S.A. indicates that installing monitoring and control systems based on programmable-logic controllers and personal computers (PLC/PC) at smaller NGL plants can improve plant economics and processing of customers' gas and increase personnel safety. Such a system gives management a means to track the performance of a plant while making significant steps to enhance employee motivation, morale, and safety. The operator has access to a large amount of information that he or she can use to analyze alarms as well as optimize plant operation in terms of safety, income, and maintenance costs. In fact, because of his advanced awareness of the state of the plant, he generally functions more in an active than a reactive mode. With a significant amount of data available on which to base decisions, the operator can quickly see the results of his actions on the entire plant without leaving his station.

  17. Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study.

    Science.gov (United States)

    Brooks, S J; Benedict, C; Burgos, J; Kempton, M J; Kullberg, J; Nordenskjöld, R; Kilander, L; Nylander, R; Larsson, E-M; Johansson, L; Ahlström, H; Lind, L; Schiöth, H B

    2013-02-01

    Obesity adversely affects frontal lobe brain structure and function. Here we sought to show that people who are obese versus those who are of normal weight over a 5-year period have differential global and regional brain volumes. Using voxel-based morphometry, contrasts were done between those who were recorded as being either obese or of normal weight over two time points in the 5 years prior to the brain scan. In a post-hoc preliminary analysis, we compared scores for obese and normal weight people who completed the trail-making task. A total of 292 subjects were examined following exclusions (for example, owing to dementia, stroke and cortical infarcts) from the Prospective Investigation of the Vasculature in Uppsala Seniors cohort with a body mass index of normal weight (obese (30 kg m(-2)). People who were obese had significantly smaller total brain volumes and specifically, significantly reduced total gray matter (GM) volume (GMV) (with no difference in white matter or cerebrospinal fluid). Initial exploratory whole brain uncorrected analysis revealed that people who were obese had significantly smaller GMV in the bilateral supplementary motor area, bilateral dorsolateral prefrontal cortex (DLPFC), left inferior frontal gyrus and left postcentral gyrus. Secondary more stringent corrected analyses revealed a surviving cluster of GMV difference in the left DLPFC. Finally, post-hoc contrasts of scores on the trail-making task, which is linked to DLPFC function, revealed that obese people were significantly slower than those of normal weight. These findings suggest that in comparison with normal weight, people who are obese have smaller GMV, particularly in the left DLPFC. Our results may provide evidence for a potential working memory mechanism for the cognitive suppression of appetite that may lower the risk of developing obesity in later life.

  18. Why have not the hairs on the feet of gecko been smaller?

    Science.gov (United States)

    Su, Yewang; He, Shijie; Hwang, Keh-Chih; Ji, Baohua

    2012-10-01

    The nanometer size of the tiny hair is the key to the secret of strong stickiness of gecko's feet, by which the hair can achieve the maximum adhesion strength that is insensitive to the interfacial flaws with substrate surface. But the question why the hairs have not been smaller is not answered yet. In this study, we derived a geometric parameter of the surface structures considering lateral interaction among hairs, which gives a critical size below which these hairs will bunch together and cause failure of the adhesion, suggesting a lower limit of the dimension of hairs on gecko's feet.

  19. Polymersomes, smaller than you think: ferrocene as a TEM probe to determine core structure

    Energy Technology Data Exchange (ETDEWEB)

    Johnston, A. H., E-mail: ahj@soton.ac.u [University of Southampton, School of Biological Sciences (United Kingdom); Dalton, P. D. [Queensland University of Technology, Institute of Health and Biomedical Innovation (Australia); Newman, T. A. [University of Southampton, School of Medicine, Clinical Neurosciences (United Kingdom)

    2010-08-15

    By incorporating ferrocene into the hydrophobic membrane of PEG-b-PCL polymersome nanoparticles it is possible to selectively visualize their core using Transmission Electron Microscopy (TEM). Two different sizes of ferrocene-loaded polymersomes with mean hydrodynamic diameters of approximately 40 and 90 nm were prepared. Image analysis of TEM pictures of these polymersomes found that the mean diameter of the core was 4-5 times smaller than the mean hydrodynamic diameter. The values obtained also allow the surface diameter and internal volume of the core to be calculated.

  20. Further records of smaller mammals from the Kalahari Gemsbok National Park

    Directory of Open Access Journals (Sweden)

    I.L. Rautenbach

    1975-07-01

    Full Text Available An earlier paper (Rautenbach 1971 summarized documented distributional data on the smaller mammals in the Kalahari Gemsbok National Park, Republic of South Africa. Since then continued field- work in this Park (e.g. Nel and Rautenbach in press has yielded more information on the distribution of some previously recorded species,whilst other species have been recorded for the first time. Collecting hasbeen concentrated on two localities in the vicinity of Twee Rivieren, two near Nossob Camp, as well as at Dankbaar in the north-central portion of the Park.

  1. Smaller Cigarette Pack as a Commitment to Smoke Less? Insights from Behavioral Economics

    OpenAIRE

    Joachim Marti; Jody Sindelar

    2015-01-01

    Cigarettes are commonly sold in packs of 20 units and therefore little is known about the potential impact of pack size on consumption. Using insights from behavioral economics, we suggest that cigarette packs smaller than the standard size may help some smokers cut back and/or quit, consistent with their long-term goals. Results from an online hypothetical purchase experiment conducted in a sample of US smokers reveal that over a third of smokers are willing to pay a price premium to purchas...

  2. Winged queens replaced by reproductives smaller than workers in Mystrium ants

    Science.gov (United States)

    Molet, Mathieu; Peeters, Christian; Fisher, Brian L.

    2007-04-01

    In ants, winged queens that are specialized for independent colony foundation can be replaced by wingless reproductives better adapted for colony fission. We studied this shift in reproductive strategy by comparing two Mystrium species from Madagascar using morphometry, allometry and dissections. Mystrium rogeri has a single dealate queen in each colony with a larger thorax than workers and similar mandibles that allow these queens to hunt during non-claustral foundation. In contrast, Mystrium ‘red’ lacks winged queens and half of the female adults belong to a wingless ‘intermorph’ caste smaller and allometrically distinct from the workers. Intermorphs have functional ovaries and spermatheca while those of workers are degenerate. Intermorphs care for brood and a few mate and reproduce making them an all-purpose caste that takes charge of both work and reproduction. However, their mandibles are reduced and inappropriate for hunting centipedes, unlike the workers’ mandibles. This together with their small thorax disallow them to perform independent colony foundation, and colonies reproduce by fission. M. rogeri workers have mandibles polymorphic in size and shape, which allow for all tasks from brood care to hunting. In M. ‘red’, colonial investment in reproduction has shifted from producing expensive winged queens to more numerous helpers. M. ‘red’ intermorphs are the first case of reproductives smaller than workers in ants and illustrate their potential to diversify their caste system for better colonial economy.

  3. HIV-Associated Distal Neuropathic Pain is Associated with Smaller Total Cerebral Cortical Gray Matter

    Science.gov (United States)

    Keltner, John R.; Fennema-Notestine, Christine; Vaida, Florin; Wang, Dongzhe; Franklin, Donald R.; Dworkin, Robert H.; Sanders, Chelsea; McCutchan, J. Allen; Archibald, Sarah L.; Miller, David J.; Kesidis, George; Cushman, Clint; Kim, Sung Min; Abramson, Ian; Taylor, Michael J.; Theilmann, Rebecca J.; Julaton, Michelle D.; Notestine, Randy J.; Corkran, Stephanie; Cherner, Mariana; Duarte, Nichole A.; Alexander, Terry; Robinson-Papp, Jessica; Gelman, Benjamin B.; Simpson, David M.; Collier, Ann C.; Marra, Christina M.; Morgello, Susan; Brown, Greg; Grant, Igor; Atkinson, J. Hampton; Jernigan, Terry L.; Ellis, Ronald J.

    2014-01-01

    Despite modern antiretroviral therapy, HIV-associated sensory neuropathy affects over 50% of HIV patients. The clinical expression of HIV neuropathy is highly variable: many individuals report few symptoms, but about half report distal neuropathic pain (DNP), making it one of the most prevalent, disabling and treatment-resistant complications of HIV disease. The presence and intensity of pain is not fully explained by the degree of peripheral nerve damage, making it unclear why some patients do, and others do not, report pain. To better understand central nervous system contributions to HIV DNP, we performed a cross-sectional analysis of structural magnetic resonance imaging (MRI) volumes in 241 HIV-infected participants from an observational multi-site cohort study at five US sites (CNS HIV Antiretroviral Treatment Effects Research Study, CHARTER). The association between DNP and the structural imaging outcomes was investigated using both linear and nonlinear (Gaussian Kernel support vector) multivariable regression, controlling for key demographic and clinical variables. Severity of DNP symptoms was correlated with smaller total cerebral cortical gray matter volume (R = −0.24; p = 0.004). Understanding the mechanisms for this association between smaller total cortical volumes and DNP may provide insight into HIV DNP chronicity and treatment-resistance. PMID:24549970

  4. Kicking Velocity and Effect on Match Performance When using a Smaller, Lighter Ball in Women's Football.

    Science.gov (United States)

    Andersen, T B; Krustrup, P; Bendiksen, M; Orntoft, C O; Randers, M B; Pettersen, S A

    2016-11-01

    The present study evaluated the effect of a smaller, lighter ball on kicking speed and technical-tactical and physical match performance in high-level adult female footballers. In the laboratory test setting, the peak ball velocity was 6% higher with the new ball (NB) than the standard ball (SB) (26.5±0.5 vs. 25.1±0.5 m·s(-1), p0.05), blood lactate (90 min: 4.7±1.7 and 4.0±1.7 mmol·l(-1); p>0.05), total distance covered (10.6±0.9 and 10.4±0.8 km; p>0.05), intense running (>16 km/h) (2.08±0.42 and 1.94±0.38 km; p>0.05) and match-induced decrement in Yo-Yo IR1 performance (28 vs. 31%, respectively, p0.05). In conclusion, high-level adult female footballers had a higher kicking speed when using a smaller, lighter ball, but no differences were observed during match-play with the 2 ball types in respect of technical-tactical and physical match performance. The physical loading was high for the players when playing with both ball types. © Georg Thieme Verlag KG Stuttgart · New York.

  5. HIV-associated distal neuropathic pain is associated with smaller total cerebral cortical gray matter.

    Science.gov (United States)

    Keltner, John R; Fennema-Notestine, Christine; Vaida, Florin; Wang, Dongzhe; Franklin, Donald R; Dworkin, Robert H; Sanders, Chelsea; McCutchan, J Allen; Archibald, Sarah L; Miller, David J; Kesidis, George; Cushman, Clint; Kim, Sung Min; Abramson, Ian; Taylor, Michael J; Theilmann, Rebecca J; Julaton, Michelle D; Notestine, Randy J; Corkran, Stephanie; Cherner, Mariana; Duarte, Nichole A; Alexander, Terry; Robinson-Papp, Jessica; Gelman, Benjamin B; Simpson, David M; Collier, Ann C; Marra, Christina M; Morgello, Susan; Brown, Greg; Grant, Igor; Atkinson, J Hampton; Jernigan, Terry L; Ellis, Ronald J

    2014-06-01

    Despite modern antiretroviral therapy, HIV-associated sensory neuropathy affects over 50 % of HIV patients. The clinical expression of HIV neuropathy is highly variable: many individuals report few symptoms, but about half report distal neuropathic pain (DNP), making it one of the most prevalent, disabling, and treatment-resistant complications of HIV disease. The presence and intensity of pain is not fully explained by the degree of peripheral nerve damage, making it unclear why some patients do, and others do not, report pain. To better understand central nervous system contributions to HIV DNP, we performed a cross-sectional analysis of structural magnetic resonance imaging volumes in 241 HIV-infected participants from an observational multi-site cohort study at five US sites (CNS HIV Anti-Retroviral Treatment Effects Research Study, CHARTER). The association between DNP and the structural imaging outcomes was investigated using both linear and nonlinear (Gaussian Kernel support vector) multivariable regression, controlling for key demographic and clinical variables. Severity of DNP symptoms was correlated with smaller total cerebral cortical gray matter volume (r = -0.24; p = 0.004). Understanding the mechanisms for this association between smaller total cortical volumes and DNP may provide insight into HIV DNP chronicity and treatment-resistance.

  6. Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment

    Science.gov (United States)

    Nopoulos, Peggy C.; Aylward, Elizabeth H.; Ross, Christopher A.; Mills, James A.; Langbehn, Douglas R.; Johnson, Hans J.; Magnotta, Vincent A.; Pierson, Ronald K.; Beglinger, Leigh J.; Nance, Martha A.; Barker, Roger A.

    2011-01-01

    Huntington’s disease is an autosomal dominant brain disease. Although conceptualized as a neurodegenerative disease of the striatum, a growing number of studies challenge this classic concept of Huntington’s disease aetiology. Intracranial volume is the tissue and fluid within the calvarium and is a representation of the maximal brain growth obtained during development. The current study reports intracranial volume obtained from an magnetic resonance imaging brain scan in a sample of subjects (n = 707) who have undergone presymptomatic gene testing. Participants who are gene-expanded but not yet manifesting the disease (prodromal Huntington’s disease) are compared with subjects who are non-gene expanded. The prodromal males had significantly smaller intracranial volume measures with a mean volume that was 4% lower compared with controls. Although the prodromal females had smaller intracranial volume measures compared with their controls, this was not significant. The current findings suggest that mutant huntingtin can cause abnormal development, which may contribute to the pathogenesis of Huntington’s disease. PMID:20923788

  7. Comet 81p/Wild 2: The Updated Stardust Coma Dust Fluence Measurement for Smaller (Sub 10-Micrometre) Particles

    Science.gov (United States)

    Price, M. C.; Kearsley, A. T.; Burchell, M. J.; Horz, Friedrich; Cole, M. J.

    2009-01-01

    Micrometre and smaller scale dust within cometary comae can be observed by telescopic remote sensing spectroscopy [1] and the particle size and abundance can be measured by in situ spacecraft impact detectors [2]. Initial interpretation of the samples returned from comet 81P/Wild 2 by the Stardust spacecraft [3] appears to show that very fine dust contributes not only a small fraction of the solid mass, but is also relatively sparse [4], with a low negative power function describing grain size distribution, contrasting with an apparent abundance indicated by the on-board Dust Flux Monitor Instrument (DFMI) [5] operational during the encounter. For particles above 10 m diameter there is good correspondence between results from the DFMI and the particle size inferred from experimental calibration [6] of measured aerogel track and aluminium foil crater dimensions (as seen in Figure 4 of [4]). However, divergence between data-sets becomes apparent at smaller sizes, especially submicrometre, where the returned sample data are based upon location and measurement of tiny craters found by electron microscopy of Al foils. Here effects of detection efficiency tail-off at each search magnification can be seen in the down-scale flattening of each scale component, but are reliably compensated by sensible extrapolation between segments. There is also no evidence of malfunction in the operation of DFMI during passage through the coma (S. Green, personal comm.), so can the two data sets be reconciled?

  8. Comparison of flexible ureterorenoscopy and mini-percutaneous nephrolithotomy in treatment of lower calyceal stones smaller than 2 cm.

    Science.gov (United States)

    Akbulut, Fatih; Kucuktopcu, Onur; Kandemir, Emre; Sonmezay, Erkan; Simsek, Abdulmuttalip; Ozgor, Faruk; Binbay, Murat; Muslumanoglu, Ahmet Yaser; Gurbuz, Gokhan

    2016-01-01

    To compare the outcomes of flexible ureterorenoscopy (F-URS) and mini-percutaneous nephrolithotomy (mini-PNL) in the treatment of lower calyceal stones smaller than 2 cm. Patients who underwent F-URS and mini-PNL for the treatment of lower calyceal stones smaller than 2 cm between March 2009 and December 2014 were retrospectively evaluated. Ninety-four patients were divided into two groups by treatment modality: F-URS (Group 1: 63 patients) and mini-PNL (Group 2: 31 patients). All patients were preoperatively diagnosed with intravenous pyelography or computed tomography. Success rates for F-URS and mini-PNL at postoperative first month were 85.7% and 90.3%, respectively. Operation time, fluoroscopy time, and hospitalization time for F-URS and mini-PNL patients were 44.40 min, 2.9 min, 22.4 h, and 91.9 min, 6.4 min, and 63.8 h, respectively. All three parameters were significantly shorter among the F-URS group (p PNL group (0.39 mg/dL vs. 1.15 mg/dL, p = 0.001). A comparison of complications according to the Clavien classification demonstrated significant differences between the groups (p = 0.001). More patients in the F-URS groups require antibiotics due to urinary tract infection, and more patients in the mini-PNL group required ureteral double J catheter insertion under general anesthesia. Although both F-URS and mini-PNL have similar success rates for the treatment of lower calyceal stones, F-URS appears to be more favorable due to shorter fluoroscopy and hospitalization times; and lower hemoglobin drops. Multicenter and studies using higher patient volumes are needed to confirm these findings.

  9. Micrometeoroid Impacts on the Hubble Space Telescope Wide Field and Planetary Camera 2: Smaller Particle Impacts

    Science.gov (United States)

    Ross, D. K.; Anz-Meador, P.; Liou, J.C.; Opiela, J.; Kearsley, A. T.; Grime, G.; Webb, R.; Jeynes, C.; Palitsin, V.; Colaux, J.; hide

    2014-01-01

    The radiator shield on the Wide Field and Planetary Camera 2 (WFPC2) was subject to optical inspection following return from the Hubble Space Telescope (HST) in 2009. The survey revealed over 600 impact features of > 300 micrometers diameter, from exposure in space for 16 years. Subsequently, an international collaborative programme of analysis was organized to determine the origin of hypervelocity particles responsible for the damage. Here we describe examples of the numerous smaller micrometeoroid (MM) impact features (< 700 micrometers diameter) which excavated zinc orthotitanate (ZOT) paint from the radiator surface, but did not incorporate material from underlying Al alloy; larger impacts are described by [3]. We discuss recognition and interpretation of impactor remains, and MM compositions found on WFPC2.

  10. TouchGrid: Touchpad pointing by recursively mapping taps to smaller display regions

    DEFF Research Database (Denmark)

    Hertzum, Morten; Hornbæk, Kasper

    2005-01-01

    Touchpad devices are widely used but lacking in pointing efficiency. The TouchGrid, an instance of what we term cell cursors, replaces moving the cursor through dragging the finger on a touchpad with tapping in different regions of the touchpad. The touchpad regions are recursively mapped...... to smaller display regions and thereby enable high-precision pointing without requiring high tapping precision. In an experiment, six subjects used the TouchGrid and a standard touchpad across different numbers of targets, distances to targets, and target widths. Whereas standard touchpad operation follows...... Fitts’ law, target selection time with the TouchGrid is a linear function of the required number of taps. The TouchGrid was significantly faster for small targets and for tasks requiring one tap, and marginally faster for two-tap tasks. Error rates tended to be higher with the TouchGrid than...

  11. The Problem with Big Data: Operating on Smaller Datasets to Bridge the Implementation Gap

    Directory of Open Access Journals (Sweden)

    Richard Mann

    2016-12-01

    Full Text Available Big datasets have the potential to revolutionize public health. However, there is a mismatch between the political and scientific optimism surrounding big data and the public’s perception of its benefit. We suggest a systematic and concerted emphasis on developing models derived from smaller datasets to illustrate to the public how big data can produce tangible benefits in the long-term. In order to highlight the immediate value of a small data approach, we produced a proof-of-concept model predicting hospital length of stay. The results demonstrate that existing small datasets can be used to create models that generate a reasonable prediction, facilitating healthcare delivery. We propose that greater attention (and funding needs to be directed toward the utilization of existing information resources in parallel with current efforts to create and exploit ‘big data’.

  12. A step toward production of smaller diameter single wall carbon nanotubes

    Directory of Open Access Journals (Sweden)

    V. Lemos

    2003-01-01

    Full Text Available Single-wall carbon nanotubes were produced with, either, a bimetallic or a mixture of three catalysts. Raman scattering and high resolution transmission electron microscopy were used as characterization tools. The mixture LiNi0.5Co0.5O2 leaded to a sample relatively free from impurities with long bundles, each containing a few tubes. A narrow distribution of diameters for the sample produced with this mixture was evidenced by Raman scattering experiences. The mean tube diameter was found to be smaller than those measured for the nanotubes obtained with the bimetallic catalysts, Fe/Ni and Ni/Co. Possible chiralities were calculated for the semiconductor nanotubes formed. Assignments of the Raman radial breathing mode frequencies to the calculated structures are presented.

  13. Opportunities and barriers for smaller portions in food service: lessons from marketing and behavioral economics.

    Science.gov (United States)

    Riis, J

    2014-07-01

    This paper uses the frameworks and evidence from marketing and behavioral economics to highlight the opportunities and barriers for portion control in food service environments. Applying Kahneman's 'thinking fast and slow' concepts, it describes 10 strategies that can be effective in 'tricking' the consumer's fast cognitive system to make better decisions and in triggering the slow cognitive system to help prevent the fast system from making bad decisions. These strategies include shrinking defaults, elongating packages, increasing the visibility of small portions, offering more mixed virtue options, adding more small sizes, offering 'right-sized' standard portions, using meaningful size labels, adopting linear pricing, using temporal landmarks to push smaller portions and facilitating pre-commitment. For each of these strategies, I discuss the specific cost and revenue barriers that a food service operator would face if the strategy were adopted.

  14. An atlas of the smaller maps in orientable and nonorientable surfaces

    CERN Document Server

    Jackson, David

    2000-01-01

    Maps are beguilingly simple structures with deep and ubiquitous properties. They arise in an essential way in many areas of mathematics and mathematical physics, but require considerable time and computational effort to generate. Few collected drawings are available for reference, and little has been written, in book form, about their enumerative aspects. An Atlas of the Smaller Maps in Orientable and Nonorientable Surfaces is the first book to provide complete collections of maps along with their vertex and face partitions, number of rootings, and an index number for cross referencing. It provides an explanation of axiomatization and encoding, and serves as an introduction to maps as a combinatorial structure. The Atlas lists the maps first by genus and number of edges, and gives the embeddings of all graphs with at most five edges in orientable surfaces, thus presenting the genus distribution for each graph. Exemplifying the use of the Atlas, the authors explore two substantial conjectures with origins in ...

  15. Higher circulating parathormone is associated with smaller and weaker bones in obese children.

    Science.gov (United States)

    Radetti, Giorgio; Franceschi, Roberto; Adami, Silvano; Longhi, Silvia; Rossini, Maurizio; Gatti, Davide

    2014-07-01

    Obese children have disadvantageous bone geometry, bone of low quality, and reduced strength at non-weight-bearing skeletal sites. The aim of our study was to investigate the role of parathormone (PTH) and the Wnt/β-catenin signaling pathway and its inhibitors, sclerostin and Dickkopf-1 (DKK1), as negative modulators of fat mass on bone. This was a cross-sectional observational study performed in 44 (26 males and 18 females) obese subjects, aged 11.41 ± 2.61 years. Thirty-seven normal-weight, healthy children (22 males and 15 females) of the same chronological age served as controls for the biochemical parameters and bone markers, while the data on bone geometry were evaluated according to our normative data obtained previously in a group of 325 control children. Digitalized X-rays were evaluated at the level of the second metacarpal bone for the determination of bone geometry: total cross-sectional area (TCSA), cortical area (CA), medullary area (MA), and bone strength (bending breaking resistance index [BBRI]). Serum bone markers (intact procollagen-1N-terminal propeptide [P1NP] and serum carboxy-terminal telopeptide of collagen-1 [CTX]), sclerostin, DKK1, PTH, 25-hydroxyvitamin D and were also measured. Data for TCSA, CA, MA, and BBRI are expressed as a standard deviation score in order to normalize them for age and sex. TCSA (mean ± SD, -2.92 ± 2.71), CA (-0.60 ± 0.82), MA (-0.45 ± 1.14), and BBRI (-2.65 ± 2.31) were all significantly smaller than in controls (p Bone turnover is higher in obese children than in controls, and this is associated with smaller and apparently weaker bones. Higher PTH and lower sclerostin levels may be responsible for these findings.

  16. Smaller self-inflating bags produce greater guideline consistent ventilation in simulated cardiopulmonary resuscitation

    Directory of Open Access Journals (Sweden)

    Boyle Malcolm J

    2009-02-01

    Full Text Available Abstract Background Suboptimal bag ventilation in cardiopulmonary resuscitation (CPR has demonstrated detrimental physiological outcomes for cardiac arrest patients. In light of recent guideline changes for resuscitation, there is a need to identify the efficacy of bag ventilation by prehospital care providers. The objective of this study was to evaluate bag ventilation in relation to operator ability to achieve guideline consistent ventilation rate, tidal volume and minute volume when using two different capacity self-inflating bags in an undergraduate paramedic cohort. Methods An experimental study using a mechanical lung model and a simulated adult cardiac arrest to assess the ventilation ability of third year Monash University undergraduate paramedic students. Participants were instructed to ventilate using 1600 ml and 1000 ml bags for a length of two minutes at the correct rate and tidal volume for a patient undergoing CPR with an advanced airway. Ventilation rate and tidal volume were recorded using an analogue scale with mean values calculated. Ethics approval was granted. Results Suboptimal ventilation with the use of conventional 1600 ml bag was common, with 77% and 97% of participants unable to achieve guideline consistent ventilation rates and tidal volumes respectively. Reduced levels of suboptimal ventilation arouse from the use of the smaller bag with a 27% reduction in suboptimal tidal volumes (p = 0.015 and 23% reduction in suboptimal minute volumes (p = 0.045. Conclusion Smaller self-inflating bags reduce the incidence of suboptimal tidal volumes and minute volumes and produce greater guideline consistent results for cardiac arrest patients.

  17. Larger N2 and smaller early contingent negative variation during the processing of uncertainty about future emotional events.

    Science.gov (United States)

    Lin, Huiyan; Gao, Hongwei; You, Jin; Liang, Jiafeng; Ma, Junpeng; Yang, Nan; Xu, Huan; Jin, Hua

    2014-12-01

    Uncertainty increases individuals' anxiety and fear. Identifying its neural processing may contribute to understanding the detrimental effects of uncertainty on well-being and psychological symptoms. Using high temporal resolution event-related potentials (ERPs), employing the classical paradigm in which neutral signs were used as certain and uncertain cues and anticipating arousal-balanced positive and negative pictures, the present study aimed to further investigate the temporal dynamics of brain activation by uncertainty about future emotional events. ERPs were recorded while participants observed uncertain cues and certain cues about future positive and negative pictures. Results showed that the uncertain cues produced larger N2 than did the certain cues about both future positive and negative pictures, and uncertain cues produced smaller early contingent negative variation (CNV) than did the certain cues about future negative pictures. The results provide evidence that the specific processing of uncertainty about future emotional events occurs at different cognitive stages.

  18. 21 September 2010 - Chairman of the Pakistan Atomic Energy Commission A. Parvez, CERN Director-General R. Heuer, Staff Association President G. Deroma, Ambassador to the UN Z. Akram (showing a symbol of the funds raised by CERN Staff for Pakistan)and Adviser for Non-Member States R. Voss.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    21 September 2010 - Chairman of the Pakistan Atomic Energy Commission A. Parvez, CERN Director-General R. Heuer, Staff Association President G. Deroma, Ambassador to the UN Z. Akram (showing a symbol of the funds raised by CERN Staff for Pakistan)and Adviser for Non-Member States R. Voss.

  19. Smaller Footprint Drilling System for Deep and Hard Rock Environments; Feasibility of Ultra-High-Speed Diamond Drilling

    Energy Technology Data Exchange (ETDEWEB)

    TerraTek, A Schlumberger Company

    2008-12-31

    The two phase program addresses long-term developments in deep well and hard rock drilling. TerraTek believes that significant improvements in drilling deep hard rock will be obtained by applying ultra-high rotational speeds (greater than 10,000 rpm). The work includes a feasibility of concept research effort aimed at development that will ultimately result in the ability to reliably drill 'faster and deeper' possibly with smaller, more mobile rigs. The principle focus is on demonstration testing of diamond bits rotating at speeds in excess of 10,000 rpm to achieve high rate of penetration (ROP) rock cutting with substantially lower inputs of energy and loads. The significance of the 'ultra-high rotary speed drilling system' is the ability to drill into rock at very low weights on bit and possibly lower energy levels. The drilling and coring industry today does not practice this technology. The highest rotary speed systems in oil field and mining drilling and coring today run less than 10,000 rpm - usually well below 5,000 rpm. This document provides the progress through two phases of the program entitled 'Smaller Footprint Drilling System for Deep and Hard Rock Environments: Feasibility of Ultra-High-Speed Diamond Drilling' for the period starting 30 June 2003 and concluding 31 March 2009. The accomplishments of Phases 1 and 2 are summarized as follows: (1) TerraTek reviewed applicable literature and documentation and convened a project kick-off meeting with Industry Advisors in attendance (see Black and Judzis); (2) TerraTek designed and planned Phase I bench scale experiments (See Black and Judzis). Improvements were made to the loading mechanism and the rotational speed monitoring instrumentation. New drill bit designs were developed to provided a more consistent product with consistent performance. A test matrix for the final core bit testing program was completed; (3) TerraTek concluded small-scale cutting performance tests; (4

  20. Smaller hippocampal volumes in patients with bipolar disorder are masked by exposure to lithium: a meta-analysis.

    Science.gov (United States)

    Hajek, Tomas; Kopecek, Miloslav; Höschl, Cyril; Alda, Martin

    2012-09-01

    Smaller hippocampal volumes relative to controls are among the most replicated neuroimaging findings in individuals with unipolar but not bipolar depression. Preserved hippocampal volumes in most studies of participants with bipolar disorder may reflect potential neuroprotective effects of lithium (Li). To investigate hippocampal volumes in patients with bipolar disorder while controlling for Li exposure, we performed a meta-analysis of neuroimaging studies that subdivided patients based on the presence or absence of current Li treatment. To achieve the best coverage of literature, we categorized studies based on whether all or a majority, or whether no or a minority of patients were treated with Li. Hippocampal volumes were compared by combining standardized differences between means (Cohen d) from individual studies using random-effects models. Overall, we analyzed data from 101 patients with bipolar disorder in the Li group, 245 patients in the non-Li group and 456 control participants from 16 studies. Both the left and right hippocampal volumes were significantly larger in the Li group than in controls (Cohen d = 0.53, 95% confidence interval [CI] 0.18 to 0.88; Cohen d = 0.51, 95% CI 0.21 to 0.81, respectively) or the non-Li group (Cohen d = 0.93, 95% CI 0.56 to 1.31; Cohen d = 1.07, 95% CI 0.70 to 1.45, respectively), which had smaller left and right hippocampal volumes than the control group (Cohen d = -0.36, 95% CI -0.55 to -0.17; Cohen d = -0.38, 95% CI -0.63 to -0.13, respectively). There was no evidence of publication bias. Missing information about the illness burden or lifetime exposure to Li and polypharmacy in some studies may have contributed to statistical heterogeneity in some analyses. When exposure to Li was minimized, patients with bipolar disorder showed smaller hippocampal volumes than controls or Li-treated patients. Our findings provide indirect support for the negative effects of bipolar disorder on hippocampal volumes and are consistent

  1. Independent practice associations and physician-hospital organizations can improve care management for smaller practices.

    Science.gov (United States)

    Casalino, Lawrence P; Wu, Frances M; Ryan, Andrew M; Copeland, Kennon; Rittenhouse, Diane R; Ramsay, Patricia P; Shortell, Stephen M

    2013-08-01

    Pay-for-performance, public reporting, and accountable care organization programs place pressures on physicians to use health information technology and organized care management processes to improve the care they provide. But physician practices that are not large may lack the resources and size to implement such processes. We used data from a unique national survey of 1,164 practices with fewer than twenty physicians to provide the first information available on the extent to which independent practice associations (IPAs) and physician-hospital organizations (PHOs) might make it possible for these smaller practices to share resources to improve care. Nearly a quarter of the practices participated in an IPA or a PHO that accounted for a significant proportion of their patients. On average, practices participating in these organizations provided nearly three times as many care management processes for patients with chronic conditions as nonparticipating practices did (10.4 versus 3.8). Half of these processes were provided only by IPAs or PHOs. These organizations may provide a way for small and medium-size practices to systematically improve care and participate in accountable care organizations.

  2. Any effects of social orientation priming on object-location memory are smaller than initially reported.

    Science.gov (United States)

    Drouin, Héloïse; Davidson, Patrick S R

    2015-12-01

    It has previously been reported that priming a collectivistic social orientation (compared with an individualistic one) boosts object-location memory (Kühnen & Oyserman, 2002; Oyserman, Sorensen, Reber, & Chen, 2009). We conducted 4 experiments to replicate this reported effect, using the same methods as in those initial reports. In Experiment 1 (n = 145), we found a hint of a priming effect on object-location memory, but also an unanticipated interaction between priming and gender. In Experiment 2 (n = 90), we included gender as a formal factor and doubled the "dosage" of the priming, yet did not see any priming effects on memory. In Experiment 3 (n = 101), we octupled the priming "dosage" and again saw no significant effects on memory. Finally, in Experiment 4 (n = 102), we performed an exact replication of the methods of the original reports and again found no priming effects on memory. Any effects of this type of social orientation priming on object-location memory appear to be smaller and/or less robust than initially thought. (c) 2015 APA, all rights reserved).

  3. SMALLER FORAMINIFERS FROM THE LOWER PERMIAN EMARAT FORMATION, EAST OF FIRUZKUH (CENTRAL ALBORZ, IRAN

    Directory of Open Access Journals (Sweden)

    HAMED YARAHMADZAHI

    2016-10-01

    Full Text Available The uppermost Carboniferous-Lower Permian Dorud Group of the Gaduk section in Central Alborz (Iran is more than 44 m-thick; it includes thick succession of conglomerates, quartzarenites, calcareous sandstones, oncolitic fusulinid limestones, sandy limestones, sandstones and shales. The Toyeh, Emarat and Shah Zeid formations of this Group were dated from the Gzhelian to the Sakmarian. A review of the uppermost Gzhelian, Asselian and lower Sakmarian smaller foraminifers of the Emarat Formation of the Gaduk section is here presented. Three foraminiferal biozones are defined: the Nodosinelloides shikhanica-Geinitzina primitiva Zone is latest Gzhelian in age; the Nodosinelloides spp.-Geinitzina spp.-Pseudoacutella partoazari Zone is Asselian; the Rectogordius iranicus gadukensis-Endothyra cf. bamberi Zone is early Sakmarian in age. A new subspecies Rectogordius iranicus gadukensis n. subsp. is described, and the genera Pseudovidalina and Grovesella are discussed. The studied assemblages are correlated with those from the Carnic Alps (Austria-Italy, East European Platform of Russia, the Urals (Russia, Darvaz (Uzbekistan, the northern and central Pamirs (Tajikistan, Central Iran, northern Afghanistan and other classical regions of the Tethyan realm.

  4. Lattice with Smaller Momentum Compaction Factor for PEP-II High Energy Ring

    CERN Document Server

    Cai, Y; Nosochkov, Yu M

    2003-01-01

    At present, the PEP-II bunch length and vertical beta function at the Interaction Point (IP) are about of the same size. To increase luminosity, it is planned to gradually reduce the IP beta function. For the maximum effect, bunch length has to be also reduced to minimize luminosity loss caused by the hourglass effect at IP. One of the methods to achieve a smaller bunch length is to reduce momentum compaction factor. This paper discusses a lattice option for the High Energy Ring, where the nominal 60 degree cells in four arcs are replaced by 90 degree cells to reduce momentum compaction factor by 30% and bunch length by 16%. The increased focusing in 90 degree cells results in 40% stronger arc quadrupoles and 150% stronger arc sextupoles due to reduced dispersion and larger chromaticity. Tracking simulations predict that dynamic aperture for this lattice will be more than 10 times the rms size of a fully coupled beam for a horizontal emittance of 30 nm and IP beta function of 1cm. The lattice modification and...

  5. High proportion of smaller ranged hummingbird species coincides with ecological specialization across the Americas

    Science.gov (United States)

    Martín González, Ana M.; Maruyama, Pietro K.; Sandel, Brody; Vizentin-Bugoni, Jeferson; Schleuning, Matthias; Abrahamczyk, Stefan; Alarcón, Ruben; Araujo, Andréa C.; Araújo, Francielle P.; Mendes de Azevedo, Severino; Baquero, Andrea C.; Cotton, Peter A.; Ingversen, Tanja Toftemark; Kohler, Glauco; Lara, Carlos; Guedes Las-Casas, Flor Maria; Machado, Adriana O.; Machado, Caio Graco; Maglianesi, María Alejandra; Moura, Alan Cerqueira; Nogués-Bravo, David; Oliveira, Genilda M.; Oliveira, Paulo E.; Ornelas, Juan Francisco; Rodrigues, Licléia da Cruz; Rosero-Lasprilla, Liliana; Rui, Ana Maria; Sazima, Marlies; Timmermann, Allan; Varassin, Isabela Galarda; Wang, Zhiheng; Watts, Stella; Fjeldså, Jon; Svenning, Jens-Christian; Rahbek, Carsten; Dalsgaard, Bo

    2016-01-01

    Ecological communities that experience stable climate conditions have been speculated to preserve more specialized interspecific associations and have higher proportions of smaller ranged species (SRS). Thus, areas with disproportionally large numbers of SRS are expected to coincide geographically with a high degree of community-level ecological specialization, but this suggestion remains poorly supported with empirical evidence. Here, we analysed data for hummingbird resource specialization, range size, contemporary climate, and Late Quaternary climate stability for 46 hummingbird–plant mutualistic networks distributed across the Americas, representing 130 hummingbird species (ca 40% of all hummingbird species). We demonstrate a positive relationship between the proportion of SRS of hummingbirds and community-level specialization, i.e. the division of the floral niche among coexisting hummingbird species. This relationship remained strong even when accounting for climate, furthermore, the effect of SRS on specialization was far stronger than the effect of specialization on SRS, suggesting that climate largely influences specialization through species' range-size dynamics. Irrespective of the exact mechanism involved, our results indicate that communities consisting of higher proportions of SRS may be vulnerable to disturbance not only because of their small geographical ranges, but also because of their high degree of specialization. PMID:26842573

  6. Smaller Forbush Decreases in Solar Cycle 24: Effect of the Weak CME Field Strength?

    Science.gov (United States)

    Thakur, N.

    2015-12-01

    A Forbush decrease (FD) is a sudden depression in the intensity of galactic cosmic ray (GCR) background, followed by a gradual recovery. One of the major causes of FDs is the presence of magnetic structures such as magnetic clouds (MCs) or corotating interaction regions (CIRs) that have enhanced magnetic field, which can scatter particles away reducing the observed GCR intensity. Recent work (Gopalswamy et al. 2014, GRL 41, 2673) suggests that coronal mass ejections (CMEs) are expanding anomalously in solar cycle 24 due to the reduced total pressure in the ambient medium. One of the consequences of the anomalous expansion is the reduced magnetic content of MCs, so we expect subdued FDs in cycle 24. In this paper, we present preliminary results from a survey of FDs during MC events in cycle 24 in comparison with those in cycle 23. We find that only ~17% FDs in cycle 24 had an amplitude >3%, as compared to ~31% in cycle 23. This result is consistent with the difference in the maximum magnetic field intensities (Bmax) of MCs in the two cycles: only ~ 10% of MCs in cycle 24 have Bmax>20nT, compared to 22% in cycle 23, confirming that MCs of cycle 24 have weaker magnetic field content. Therefore, we suggest that weaker magnetic field intensity in the magnetic clouds of cycle 24 has led to FDs with smaller amplitudes.

  7. CONCEPTUAL DESIGN FOR A RADICALLY SMALLER, HIGHLY ADAPTIVE AND APPLICATION-FLEXIBLE MINING MACHINE FOR UTILITY AND DEVELOPMENT WORK

    Energy Technology Data Exchange (ETDEWEB)

    Andrew H. Stern

    2004-12-20

    The aim of this research project was to develop a preliminary ''conceptual design'' for a radically smaller, highly adaptive and application-flexible underground coal mining machine, for performing non-production utility work and/or also undertake limited production mining for the recovery of reserves that would otherwise be lost. Whereas historically, mining philosophies have reflected a shift to increasing larger mechanized systems [such as the continuous miner (CM)], specific mining operations that do not benefit from the economy of the large mining equipment are often ignored or addressed with significant inefficiencies. Developing this prototype concept will create a new class of equipment that can provide opportunities to re-think the very structure of the mining system across a broad range of possibilities, not able to be met by existing machinery. The approach involved pooling the collective input from mining professionals, using a structured listing of desired inputs in the form of a questionnaire, which was used to define the range of desired design specifications. From these inputs, a conceptual specification was blended, by the author, to embody the general concurrence of mission concepts for this machine.

  8. Faster diffraction-based overlay measurements with smaller targets using 3D gratings

    Science.gov (United States)

    Li, Jie; Kritsun, Oleg; Liu, Yongdong; Dasari, Prasad; Volkman, Catherine; Hu, Jiangtao

    2012-03-01

    Diffraction-based overlay (DBO) technologies have been developed to address the overlay metrology challenges for 22nm technology node and beyond. Most DBO technologies require specially designed targets that consist of multiple measurement pads, which consume too much space and increase measurement time. The traditional empirical approach (eDBO) using normal incidence spectroscopic reflectometry (NISR) relies on linear response of the reflectance with respect to overlay displacement within a small range. It offers convenience of quick recipe setup since there is no need to establish a model. However it requires three or four pads per direction (x or y) which adds burden to throughput and target size. Recent advances in modeling capability and computation power enabled mDBO, which allows overlay measurement with reduced number of pads, thus reducing measurement time and DBO target space. In this paper we evaluate the performance of single pad mDBO measurements using two 3D targets that have different grating shapes: squares in boxes and L-shapes in boxes. Good overlay sensitivities are observed for both targets. The correlation to programmed shifts and image-based overlay (IBO) is excellent. Despite the difference in shapes, the mDBO results are comparable for square and L-shape targets. The impact of process variations on overlay measurements is studied using a focus and exposure matrix (FEM) wafer. Although the FEM wafer has larger process variations, the correlation of mDBO results with IBO measurements is as good as the normal process wafer. We demonstrate the feasibility of single pad DBO measurements with faster throughput and smaller target size, which is particularly important in high volume manufacturing environment.

  9. Birds and Roads: Reduced Transit for Smaller Species over Roads within an Urban Environment

    Directory of Open Access Journals (Sweden)

    Christopher D. Johnson

    2017-05-01

    important role in determining species presence and crossing likelihood. Dense vegetation is known to benefit smaller species due to the provision of foraging resources and shelter from larger, more aggressive species.

  10. The moving minimum audible angle is smaller during self motion than during source motion.

    Directory of Open Access Journals (Sweden)

    W. Owen eBrimijoin

    2014-09-01

    Full Text Available We are rarely perfectly still: our heads rotate in three axes and move in three dimensions, constantly varying the spectral and binaural cues at the ear drums. In spite of this motion, static sound sources in the world are typically perceived as stable objects. This argues that the auditory system – in a manner not unlike the vestibulo-ocular reflex – works to compensate for self motion and stabilize our sensory representation of the world. We tested a prediction arising from this postulate: that self motion should be processed more accurately than source motion.We used an infrared motion tracking system to measure head angle, and real-time interpolation of head related impulse responses to create head-stabilized signals that appeared to remain fixed in space as the head turned. After being presented with pairs of simultaneous signals consisting of a man and a woman speaking a snippet of speech, normal and hearing impaired listeners were asked to report whether the female voice was to the left or the right of the male voice. In this way we measured the moving minimum audible angle (MMAA. This measurement was made while listeners were asked to turn their heads back and forth between ± 15° and the signals were stabilized in space. After this self-motion condition we measured MMAA in a second source-motion condition when listeners remained still and the virtual locations of the signals were moved using the trajectories from the first condition.For both normal and hearing impaired listeners, we found that the MMAA for signals moving relative to the head was ~1-2° smaller when the movement was the result of self motion than when it was the result of source motion, even though the motion with respect to the head was identical. These results as well as the results of past experiments suggest that spatial processing involves an ongoing and highly accurate comparison of spatial acoustic cues with self-motion cues.

  11. Generalized Orthogonal Matching Pursuit

    CERN Document Server

    Wang, Jian; Shim, Byonghyo

    2011-01-01

    As a greedy algorithm to recover sparse signals from compressed measurements, the orthogonal matching pursuit (OMP) algorithm has received much attention in recent years. In this paper, we introduce an extension of the orthogonal matching pursuit (gOMP) for pursuing efficiency in reconstructing sparse signals. Our approach, henceforth referred to as generalized OMP (gOMP), is literally a generalization of the OMP in the sense that multiple indices are identified per iteration. Owing to the selection of multiple "correct" indices, the gOMP algorithm is finished with much smaller number of iterations compared to the OMP. We show that the gOMP can perfectly reconstruct any $K$-sparse signals ($K > 1$), provided that the sensing matrix satisfies the RIP with $\\delta_{NK} < \\frac{\\sqrt{N}}{\\sqrt{K} + 2 \\sqrt{N}}$. We also demonstrate by empirical simulations that the gOMP has excellent recovery performance comparable to $\\ell_1$-minimization technique with fast processing speed and competitive computational com...

  12. Rematching AGS Booster synchrotron injection lattice for smaller transverse beam emittances

    Energy Technology Data Exchange (ETDEWEB)

    Liu, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Beebe-Wang, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Brown, K. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gardner, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Huang, H. [Brookhaven National Lab. (BNL), Upton, NY (United States); Minty, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Schoefer, V. [Brookhaven National Lab. (BNL), Upton, NY (United States); Zeno, K. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-01-25

    The polarized proton beam is injected into the booster via the charge-exchange (H- to H+) scheme. The emittance growth due to scattering at the stripping foil is proportional to the beta functions at the foil. It was demonstrated that the current scheme of reducing the beta functions at the stripping foil preserves the emittance better; however the betatron tunes are above but very close to half integer. Due to concern of space charge and half integer in general, options of lattice designs aimed towards reducing the beta functions at the stripping foil with tunes at more favorable places are explored.

  13. Smaller than expected cognitive deficits in schizophrenia patients from the population-representative ABC catchment cohort.

    Science.gov (United States)

    Lennertz, Leonhard; An der Heiden, Wolfram; Kronacher, Regina; Schulze-Rauschenbach, Svenja; Maier, Wolfgang; Häfner, Heinz; Wagner, Michael

    2016-08-01

    Most neuropsychological studies on schizophrenia suffer from sample selection bias, with male and chronic patients being overrepresented. This probably leads to an overestimation of cognitive impairments. The present study aimed to provide a less biased estimate of cognitive functions in schizophrenia using a population-representative catchment area sample. Schizophrenia patients (N = 89) from the prospective Mannheim ABC cohort were assessed 14 years after disease onset and first diagnosis, using a comprehensive neuropsychological test battery. A healthy control group (N = 90) was carefully matched according to age, gender, and geographic region (city, rural surrounds). The present sample was representative for the initial ABC cohort. In the comprehensive neuropsychological assessment, the schizophrenia patients were only moderately impaired as compared to the healthy control group (d = 0.56 for a general cognitive index, d = 0.42 for verbal memory, d = 0.61 for executive functions, d = 0.69 for attention). Only 33 % of the schizophrenia patients scored one standard deviation unit below the healthy control group in the general cognitive index. Neuropsychological performance did not correlate with measures of the clinical course including age at onset, number of hospital admissions, and time in paid work. Thus, in this population-representative sample of schizophrenia patients, neuropsychological deficits were less pronounced than expected from meta-analyses. In agreement with other epidemiological studies, this suggests a less devastating picture of cognition in schizophrenia.

  14. Harvey, Mark S. (2003: Catalogue of the smaller arachnid orders of the world: Amblypygi, Uropygi, Schizomida, Palpigradi, Ricinulei and Solifugae

    Directory of Open Access Journals (Sweden)

    Blick, Theo

    2004-11-01

    Full Text Available book review: Harvey Mark S. (2003: Catalogue of the smaller arachnid orders of the world: Amblypygi, Uropygi, Schizomida, Palpigradi, Ricinulei and Solifugae. Includes checklists for Europe of: Amblypygi, Uropygi, Schizomida, Palpigradi, Solifugae.

  15. Sewerage Treatment Plants, Published in 1998, Smaller than 1:100000 scale, Peachtree City Water and Sewerage Authority.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Sewerage Treatment Plants dataset, published at Smaller than 1:100000 scale, was produced all or in part from Hardcopy Maps information as of 1998. Data by...

  16. Cellular Phone Towers, Published in 1995, Smaller than 1:100000 scale, Garrett County Planning & Land Development.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at Smaller than 1:100000 scale, was produced all or in part from Published Reports/Deeds information as of 1995. Data...

  17. Ravens, New Caledonian crows and jackdaws parallel great apes in motor self-regulation despite smaller brains.

    Science.gov (United States)

    Kabadayi, Can; Taylor, Lucy A; von Bayern, Auguste M P; Osvath, Mathias

    2016-04-01

    Overriding motor impulses instigated by salient perceptual stimuli represent a fundamental inhibitory skill. Such motor self-regulation facilitates more rational behaviour, as it brings economy into the bodily interaction with the physical and social world. It also underlies certain complex cognitive processes including decision making. Recently, MacLean et al. (MacLean et al. 2014 Proc. Natl Acad. Sci. USA 111, 2140-2148. (doi:10.1073/pnas.1323533111)) conducted a large-scale study involving 36 species, comparing motor self-regulation across taxa. They concluded that absolute brain size predicts level of performance. The great apes were most successful. Only a few of the species tested were birds. Given birds' small brain size-in absolute terms-yet flexible behaviour, their motor self-regulation calls for closer study. Corvids exhibit some of the largest relative avian brain sizes-although small in absolute measure-as well as the most flexible cognition in the animal kingdom. We therefore tested ravens, New Caledonian crows and jackdaws in the so-called cylinder task. We found performance indistinguishable from that of great apes despite the much smaller brains. We found both absolute and relative brain volume to be a reliable predictor of performance within Aves. The complex cognition of corvids is often likened to that of great apes; our results show further that they share similar fundamental cognitive mechanisms.

  18. Hepatocellular carcinomas smaller than 4 cm supplied by the intercostal artery: can we predict which intercostal artery supplies the tumor?

    Science.gov (United States)

    Hur, Saebeom; Kim, Hyo-Cheol; Chung, Jin Wook; Kim, Min-Uk; Kim, Ji Dae; Kim, Gyoung Min; Lee, In Joon; Kim, Young Il; Jae, Hwan Jun; Park, Jae Hyung

    2011-01-01

    To predict which intercostal artery supplies a tumor by examining the spatial relationship between hepatocellular carcinoma (HCC) and the intercostal artery feeding the tumor on transverse computed tomography (CT) images. Between January 2000 and September 2009, 46 intercostal arteries supplying HCCs smaller than 4 cm were noted in 44 patients, and CT scans and angiograms of these patients were retrospectively reviewed. The intercostal artery feeding the tumor was marked on the CT scan showing the center of the tumor. In addition, its spatial relationship with the tumor center was examined. The angle of the tumor location was measured on the transverse CT scan in the clockwise direction from the sagittal line on the virtual circle centered in the right hemithorax. Correlations between the angle of the tumor location and the level of the tumor-feeding intercostal artery were assessed with the Spearman rank coefficient. Of 46 intercostal arteries feeding HCC, 39 (85%) were the first ones observed from the tumor center in a counterclockwise direction on the transverse CT image containing the tumor center. The level of the tumor-feeding intercostal artery was significantly correlated with the angle of the tumor, as the posteriorly located tumor tends to be supplied by lower intercostal arteries, while the laterally located tumor by upper intercostal arteries (Spearman coefficient = -0.537; p intercostal artery encountered from the tumor center in a counterclockwise direction on a transverse CT image.

  19. Hepatocellular Carcinomas Smaller Than 4 cm Supplied by the Intercostal Artery: Can We Predict Which Intercostal Artery Supplies the Tumor?

    Energy Technology Data Exchange (ETDEWEB)

    Hur, Sae Beom; Kim, Hyo Cheol; Chung, Jin Wook [Seoul National University Hospital, Seoul National University College of Medicine, Seoul (Korea, Republic of); and others

    2011-11-15

    To predict which intercostal artery supplies a tumor by examining the spatial relationship between hepatocellular carcinoma (HCC) and the intercostal artery feeding the tumor on transverse computed tomography (CT) images. Between January 2000 and September 2009, 46 intercostal arteries supplying HCCs smaller than 4 cm were noted in 44 patients, and CT scans and angiograms of these patients were retrospectively reviewed. The intercostal artery feeding the tumor was marked on the CT scan showing the center of the tumor. In addition, its spatial relationship with the tumor center was examined. The angle of the tumor location was measured on the transverse CT scan in the clockwise direction from the sagittal line on the virtual circle centered in the right hemithorax. Correlations between the angle of the tumor location and the level of the tumor-feeding intercostal artery were assessed with the Spearman rank coefficient. Of 46 intercostal arteries feeding HCC, 39 (85%) were the first ones observed from the tumor center in a counterclockwise direction on the transverse CT image containing the tumor center. The level of the tumor-feeding intercostal artery was significantly correlated with the angle of the tumor, as the posteriorly located tumor tends to be supplied by lower intercostal arteries, while the laterally located tumor by upper intercostal arteries (Spearman coefficient = -0.537; p < 0.001). We can predict the tumor feeder with an accuracy of 85% as the first intercostal artery encountered from the tumor center in a counterclockwise direction on a transverse CT image.

  20. Mannose-binding lectin deficiency is associated with smaller infarction size and favorable outcome in ischemic stroke patients.

    Directory of Open Access Journals (Sweden)

    Michael Osthoff

    Full Text Available BACKGROUND: The Mannose-binding lectin (MBL pathway of complement plays a pivotal role in the pathogenesis of ischemia/reperfusion (I/R injury after experimental ischemic stroke. As comparable data in human ischemic stroke are limited, we investigated in more detail the association of MBL deficiency with infarction volume and functional outcome in a large cohort of patients receiving intravenous thrombolysis or conservative treatment. METHODOLOGY/PRINCIPAL FINDINGS: In a post hoc analysis of a prospective cohort study, admission MBL concentrations were determined in 353 consecutive patients with an acute ischemic stroke of whom 287 and 66 patients received conservative and thrombolytic treatment, respectively. Stroke severity, infarction volume, and functional outcome were studied in relation to MBL concentrations at presentation to the emergency department. MBL levels on admission were not influenced by the time from symptom onset to presentation (p = 0.53. In the conservative treatment group patients with mild strokes at presentation, small infarction volumes or favorable outcomes after three months demonstrated 1.5 to 2.6-fold lower median MBL levels (p = 0.025, p = 0.0027 and p = 0.046, respectively compared to patients with more severe strokes. Moreover, MBL deficient patients (<100 ng/ml were subject to a considerably decreased risk of an unfavorable outcome three months after ischemic stroke (adjusted odds ratio 0.38, p<0.05 and showed smaller lesion volumes (mean size 0.6 vs. 18.4 ml, p = 0.0025. In contrast, no association of MBL concentration with infarction volume or functional outcome was found in the thrombolysis group. However, the small sample size limits the significance of this observation. CONCLUSIONS: MBL deficiency is associated with smaller cerebral infarcts and favorable outcome in patients receiving conservative treatment. Our data suggest an important role of the lectin pathway in the pathophysiology

  1. Negotiating Managerial Legitimacy in Smaller Organizations: Management Education, Technical Skill, and Situated Competence.

    Science.gov (United States)

    Taylor, Scott; Thorpe, Richard; Down, Simon

    2002-01-01

    Case studies of four British companies showed that management legitimacy and authority were negotiated along the axes of technical expertise and abstract knowledge. Employees required evidence of management competence, and structural indicators such as management degrees or courses did not confer unquestioned legitimacy. (Contains 62 references.)…

  2. Neurons in the Fusiform Gyrus are Fewer and Smaller in Autism

    Science.gov (United States)

    van Kooten, Imke A. J.; Palmen, Saskia J. M. C.; von Cappeln, Patricia; Steinbusch, Harry W. M.; Korr, Hubert; Heinsen, Helmut; Hof, Patrick R.; van Engeland, Herman; Schmitz, Christoph

    2008-01-01

    Abnormalities in face perception are a core feature of social disabilities in autism. Recent functional magnetic resonance imaging studies showed that patients with autism could perform face perception tasks. However, the fusiform gyrus (FG) and other cortical regions supporting face processing in controls are hypoactive in patients with autism.…

  3. Neurons in the Fusiform Gyrus are Fewer and Smaller in Autism

    Science.gov (United States)

    van Kooten, Imke A. J.; Palmen, Saskia J. M. C.; von Cappeln, Patricia; Steinbusch, Harry W. M.; Korr, Hubert; Heinsen, Helmut; Hof, Patrick R.; van Engeland, Herman; Schmitz, Christoph

    2008-01-01

    Abnormalities in face perception are a core feature of social disabilities in autism. Recent functional magnetic resonance imaging studies showed that patients with autism could perform face perception tasks. However, the fusiform gyrus (FG) and other cortical regions supporting face processing in controls are hypoactive in patients with autism.…

  4. Analysis of Smaller UGR-A Meal Modules to Support Village Stability Operations

    Science.gov (United States)

    2013-09-09

    nutritionally  balanced menus.  For multiple  reasons, but most importantly the general chaos associated with early stage deployment supply chains  and the...Total Dess.  APPLE PIE, INDIVIDUAL SLICES  Case  1  48      0  0  0  0  0  0  0  0  0  1  0  0  0  0  0  0  1  5  Dess.  CHOCOLATE  CHUNK COOKIE  Case...2  24      0  1  0  0  0  0  0  0  0  0  0  0  0  0  0  0  1  5  Dess.  CHOCOLATE  CHUNK MACADAMIA  Case  2  24      0  0  0  0  0  0  0  0  0  0  1  0

  5. Master apical file size - smaller or larger: a systematic review of microbial reduction.

    Science.gov (United States)

    Aminoshariae, A; Kulild, J

    2015-11-01

    The purpose of this systematic review was to determine, in patients undergoing root canal treatment, whether apical enlargement of canals affected microbial reduction. A PICO (population, intervention, comparison and outcome) strategy was developed to identify previously published studies dealing with apical size of canal and microbial reduction. The MEDLINE, Embase, Cochrane and PubMed databases were searched. Additionally, the bibliographies of all relevant articles and textbooks were manually searched. Based on inclusion and exclusion criteria, two reviewers independently selected the relevant articles. Due to the variety of methodologies and different techniques used to measure outcome for master apical file enlargement, it was not possible to standardize the research data and to apply a meta-analysis. Seven articles were identified that met the inclusion criteria. Five of the seven articles generally concluded that canal enlargement reduced bioburden in the root canal system. Two articles reported no difference in canals enlarged to size 25 or 40. The results of the systematic review confirmed that more evidence-based research in this area is needed. With the limited information currently available, the best current available clinical evidence suggests that contemporary chemomechanical debridement techniques with canal enlargement techniques do not eliminate bacteria during root canal treatment at any size.

  6. Generalized Parabolas

    Science.gov (United States)

    Joseph, Dan; Hartman, Gregory; Gibson, Caleb

    2011-01-01

    In this article we explore the consequences of modifying the common definition of a parabola by considering the locus of all points equidistant from a focus and (not necessarily linear) directrix. The resulting derived curves, which we call "generalized parabolas," are often quite beautiful and possess many interesting properties. We show that…

  7. Generalized derivations and general relativity

    CERN Document Server

    Heller, M; Pysiak, L; Sasin, W

    2013-01-01

    We construct differential geometry (connection, curvature, etc.) based on generalized derivations of an algebra A. Such a derivation, introduced by Bresar in 1991, is given by a linear mapping u: A -> A such that there exists a usual derivation d of A satisfying the generalized Leibniz rule u(a b) = u(a) b + a d(b) for all a,b in A. The generalized geometry "is tested" in the case of the algebra of smooth functions on a manifold. We then apply this machinery to study the generalized general relativity. We define the Einstein-Hilbert action and deduce from it Einstein's field equations. We show that for a special class of metrics containing, besides the usual metric components, only one non-zero term, the action reduces to O'Hanlon action that is a Brans-Dicke action with potential and with the parameter \\omega equal to zero. We also show that the generalized Einstein equations (with zero energy-stress tensor) are equivalent to those of the Kaluza-Klein theory satisfying a "modified cylinder condition" and hav...

  8. CITM: Asian's Largest Travel Show

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Jointly hosted by China National Tourism Administration, Yunnan Provincial People's Government and General Administration of Civil Aviation of China, China International Travel Mart (CITM) is a major step to develop inbound tourism, to increase tourism receipts in foreign exchanges, and to enhance the international status of China's tourism industry.

  9. Accelerating Steered Molecular Dynamics: Toward Smaller Velocities in Forced Unfolding Simulations.

    Science.gov (United States)

    Mücksch, Christian; Urbassek, Herbert M

    2016-03-08

    The simulation of forced unfolding experiments, in which proteins are pulled apart, is conventionally done using steered molecular dynamics. We present here a hybrid scheme in which accelerated molecular dynamics is used together with steered molecular dynamics. We show that the new scheme changes the force-distance curves mainly in the region around the force maximum and thus demonstrate that the improved equilibration of the protein-solvent system brought about by using accelerated molecular dynamics makes the simulation more comparable to experimental data.

  10. Extracorporeal shockwave lithotripsy for lower pole calculi smaller than one centimeter

    Directory of Open Access Journals (Sweden)

    Christian Chaussy

    2008-01-01

    When complete stone-free status is the primary goal , follow-up examinations with new radiological technologies like spiral CT show that the stone-free rate of ESWL and endoscopically treated patients (RIRS does not differ significantly. However, in comparison to endoscopic stone removal, shockwave therapy is noninvasive, anesthesia-free and can be performed in an outpatient setup. Therefore, ESWL remains the first choice option for the treatment of lower caliceal stones up to 1 cm. The patient will definitely favour this procedure.

  11. Smaller calcite lattice deformation caused by occluded organic material in coccoliths than in mollusk shell

    DEFF Research Database (Denmark)

    Frølich, Simon; Sørensen, Henning Osholm; Hakim, Sepideh Sadat

    2015-01-01

    The growth and nucleation of biominerals are directed and affected by associated biological molecules. In this paper, we investigate the influence of occluded biomolecules on biogenic calcite from the coccolithophorid Pleurochrysis carterae and from chalk, a rock composed predominantly of fossil....... Two heating cycles allow us to differentiate the effects of thermal agitation and organic molecules. Single peak analysis and Rietveld refinement were combined to show significant differences resulting from the occluded biomolecules on the mineral phase in biogenic calcite in the mollusk shell....... This suggests that the interaction between biomolecules and calcite is not as tight in the coccoliths as in the shell. Although the shape of chalk has been preserved over millions of years, no major influence on the crystal lattice was observed in the chalk samples....

  12. Rising Threshold Shows Export Ambition

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Beginning from March 1 of this year,China only allows authorized manufacturers to engage in automobile exports in an effort to raise auto quality.The licensing system,jointly introduced by Ministry of Commerce,National Development and Reform Commission,General Administration of Customs,State Quality Inspection Administration and Certification and Accreditation Administration of China,aims to ensure that only large and credible auto manufacturers take part in auto exports.

  13. Dispositional mindfulness co-varies with smaller amygdala and caudate volumes in community adults.

    Directory of Open Access Journals (Sweden)

    Adrienne A Taren

    Full Text Available Mindfulness, a psychological process reflecting attention and awareness to what is happening in the present moment, has been associated with increased well-being and decreased depression and anxiety in both healthy and patient populations. However, little research has explored underlying neural pathways. Recent work suggests that mindfulness (and mindfulness training interventions may foster neuroplastic changes in cortico-limbic circuits responsible for stress and emotion regulation. Building on this work, we hypothesized that higher levels of dispositional mindfulness would be associated with decreased grey matter volume in the amgydala. In the present study, a self-report measure of dispositional mindfulness and structural MRI images were obtained from 155 healthy community adults. Volumetric analyses showed that higher dispositional mindfulness is associated with decreased grey matter volume in the right amygdala, and exploratory analyses revealed that higher dispositional mindfulness is also associated with decreased grey matter volume in the left caudate. Moreover, secondary analyses indicate that these amygdala and caudate volume associations persist after controlling for relevant demographic and individual difference factors (i.e., age, total grey matter volume, neuroticism, depression. Such volumetric differences may help explain why mindful individuals have reduced stress reactivity, and suggest new candidate structural neurobiological pathways linking mindfulness with mental and physical health outcomes.

  14. Mediterranean species of Caulerpa are polyploid with smaller genomes in the invasive ones.

    Directory of Open Access Journals (Sweden)

    Elena Varela-Álvarez

    Full Text Available Caulerpa species are marine green algae, which often act as invasive species with rapid clonal proliferation when growing outside their native biogeographical borders. Despite many publications on the genetics and ecology of Caulerpa species, their life history and ploidy levels are still to be resolved and are the subject of large controversy. While some authors claimed that the thallus found in nature has a haplodiplobiontic life cycle with heteromorphic alternation of generations, other authors claimed a diploid or haploid life cycle with only one generation involved. DAPI-staining with image analysis and microspectrophotometry were used to estimate relative nuclear DNA contents in three species of Caulerpa from the Mediterranean, at individual, population and species levels. Results show that ploidy levels and genome size vary in these three Caulerpa species, with a reduction in genome size for the invasive ones. Caulerpa species in the Mediterranean are polyploids in different life history phases; all sampled C. taxifolia and C. racemosa var. cylindracea were in haplophasic phase, but in C. prolifera, the native species, individuals were found in both diplophasic and haplophasic phases. Different levels of endopolyploidy were found in both C. prolifera and C. racemosa var. cylindracea. Life history is elucidated for the Mediterranean C. prolifera and it is hypothesized that haplophasic dominance in C. racemosa var. cylindracea and C. taxifolia is a beneficial trait for their invasive strategies.

  15. The more your mind wanders, the smaller your attentional blink: an individual differences study.

    Science.gov (United States)

    Thomson, David R; Ralph, Brandon C W; Besner, Derek; Smilek, Daniel

    2015-01-01

    The present studies investigate the hypothesis that individuals who frequently report experiencing episodes of mind wandering do so because they under-invest attentional/executive resources in the external environment. Here we examined whether self-reported instances of mind wandering predict the magnitude of the "attentional blink" (AB) in a rapid serial visual presentation (RSVP) task, since a prominent view is that the AB derives from an over-investment of attention in the information stream. Study 1 demonstrates that subjective reports of mind wandering in a sustained attention task have a negative predictive relation with respect to the magnitude of the AB measured in a subsequent RSVP task. In addition, using the Spontaneous and Deliberate Mind Wandering Questionnaire in Study 2, we were again able to show that trait-level mind wandering in everyday life negatively predicts AB magnitude. We suggest that mind wandering may be the behavioural outcome of an adaptive cognitive style intended to maximize the efficient processing of dynamic and temporally unpredictable events.

  16. The SE sector of the Middle Weichselian Eurasian Ice Sheet was much smaller than assumed

    Science.gov (United States)

    Räsänen, Matti E.; Huitti, Janne V.; Bhattarai, Saroj; Harvey, Jerry; Huttunen, Sanna

    2015-08-01

    Quaternary climatic and glacial history must be known in order to understand future environments. Reconstructions of the last Weichselian glacial cycle 117,000-11,700 years (kyr) ago propose that S Finland, adjacent Russia and the Baltic countries in the SE sector of the Eurasian Ice Sheet (EIS), were glaciated during the Middle Weichselian time [marine isotope stage (MIS) 4, 71-57 kyr ago] and that this glaciation was preceded in S Finland by an Early Weichselian interstadial (MIS 5c, 105-93 kyr ago) with pine forest. We apply glacial sequence stratigraphy to isolated Late Pleistocene onshore outcrop sections and show, that these events did not take place. The one Late Weichselian glaciation (MIS 2, 29-11 kyr ago) was preceded in S Finland by a nearly 90 kyr non-glacial period, featuring tundra with permafrost and probably birch forest. Our new Middle Weichselian paleoenvironmental scenario revises the configuration and hydrology of the S part of EIS and gives new setting for the evolution of Scandinavian biota. If future development during the coming glacial cycle proves to be similar, the high-level nuclear waste stored in the bedrock of SW Finland should be located deeper than currently planned, i.e. below any possible future permafrost.

  17. Support strengthening of the environment ISO acquisition of the smaller enterprises; Chushokigyo no kankyo ISO shutoku no shien kyoka

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    Tokyo Metropolis Tokyo Metropolis strengthens the support business of the environment load decrease activities for the smaller enterprises. It is because the degree of recognition that it faces in the environment ISO of the smaller enterprises rises the number of applications for 99 is 12 cases of the former year of 2 times by the authentication acquisition aid of the international environment control, inspection standard `ISO14001` begun in 1998. Furthermore, `a simple edition 14001 business` was introduced from April, and what acquired authentication individually on the cost side started support to the smaller enterprises, which it is difficult for, too. A part of the acquisition cost is granted by the authentication acquisition aid. (translated by NEDO)

  18. GENERAL EQUILIBRIUM

    Directory of Open Access Journals (Sweden)

    Monique Florenzano

    2008-09-01

    Full Text Available General equilibrium is a central concept of economic theory. Unlike partial equilibrium analysis which study the equilibrium of a particular market under the clause “ceteris paribus” that revenues and prices on the other markets stay approximately unaffected, the ambition of a general equilibrium model is to analyze the simultaneous equilibrium in all markets of a competitive economy. Definition of the abstract model, some of its basic results and insights are presented. The important issues of uniqueness and local uniqueness of equilibrium are sketched; they are the condition for a predictive power of the theory and its ability to allow for statics comparisons. Finally, we review the main extensions of the general equilibrium model. Besides the natural extensions to infinitely many commodities and to a continuum of agents, some examples show how economic theory can accommodate the main ideas in order to study some contexts which were not thought of by the initial model

  19. Small is beautiful but smaller is the aim: Review of a life of research

    Directory of Open Access Journals (Sweden)

    Curtis A. S. G.

    2004-10-01

    Full Text Available Background and origins of research of Adam Curtis. One persisting theme has been the pursuit of different landscapes at different scales to discover the routes to explain how the body is built. His research life fell in a fortunate period during which techniques and concepts for investigating structure have improved year by year. His most fortunate encounter was with Michael Abercrombie and his views on the social behaviour of cells, aims for quantitation, and statistical testing. Adam worked in various environments - in turn Geology as an undergraduate, Biophysics Ph.D. in a Genetics department and various departments in turn from anatomy via zoology to Cell Biology. Adam started his Ph.D. work in cell adhesion, studying cell movement, trapping and reaggregation phenomena, having an early start from the physico-chemical viewpoint. He made quantitative measurements of cell adhesion by kinetic methods. Interference reflection microscopy (IRM and related optical interference techniques were brought into the field of biology by him. In turn this led with Chris Wilkinson, a long term colleague, to the use of micro- and nanofabrication for biological research. Polscope and photoelastic measurements were introduced to biology recently in his laboratory. One long term theme has been to map the adhesion of cells to substrates to discover contact areas. Early data came from IRM and then TIRF (Total Internal Reflection Fluorescence Microscopy and then from Forster Resonance Energy Microscopy (FRET. Another important theme was the time scale that needed to be measured - very short indeed in suspension. This was very difficult and has only become possible very recently but hydrodynamic calculation shows it must be very short. The attractions of the Derjagin-Landau-Verwey-Overbeek theory (DLVO theory are that they explain many features of biological adhesion. The main test of this theory depends upon the energy of the adhesion at various different separation

  20. Interpretation of Continental Scale Gravity Signatures from GOCE at Smaller Scale Mineral Hosting outcrops

    Science.gov (United States)

    Braitenberg, C. F.

    2014-12-01

    The GOCE gravity field is globally homogeneous at the resolution of about 50km or better allowing for the first time to analyze tectonic structures on the continental scale. Geologic correlation studies propose to continue the tectonic lineaments across continents to the pre-breakup position. Tectonic events that induce density changes, as metamorphic events and magmatic events, should then show up in the gravity field. Applying geodynamic plate reconstructions to the GOCE gravity field places today's observed field at the pre-breakup position (Braitenberg, 2014). The same reconstruction can be applied to the seismic velocity models, to allow a joint gravity-velocity analysis. The geophysical fields bear information to control the likeliness of the hypothesized continuation of lineations. Total absence of a signal, makes the cross-continental continuation of the lineament unprobable, as continental-wide lineaments are controlled by rheologic and compositional differences of crust and upper mantle. Special attention is given to Greenstone belts, which are associated to a class of important mineralizations. The outcrops are limited in extent, but are associated with a much broader gravity signature, which cannot be explained by the outcropping masses alone. The gravity requires a mass source residing at lower crustal level, giving evidence of the mantle-crust melting processes influencing the tectonic characteristic at surface. The study is carried out over the African and South American continents. Reference Braitenberg C. (2014). Exploration of tectonic structures with GOCE in Africa and across-continents. International Journal of Applied Earth Observation and Geoinformation, doi:10.1016/j.jag.2014.013

  1. Kicking Velocity and Effect on Match Performance When using a Smaller, Lighter Ball in Women’s Football

    DEFF Research Database (Denmark)

    Andersen, Thomas Bull; Krustrup, Peter; Bendiksen, Mads;

    2016-01-01

    The present study evaluated the effect of a smaller, lighter ball on kicking speed and technical-tactical and physical match performance in high-level adult female footballers. In the laboratory test setting, the peak ball velocity was 6% higher with the new ball (NB) than the standard ball (SB...... in passing success rate (NB: 68±1% and SB: 68±1%, p>0.05). In conclusion, high-level adult female footballers had a higher kicking speed when using a smaller, lighter ball, but no differences were observed during match-play with the 2 ball types in respect of technical-tactical and physical match performance...

  2. Planning a Successful Tech Show

    Science.gov (United States)

    Nikirk, Martin

    2011-01-01

    Tech shows are a great way to introduce prospective students, parents, and local business and industry to a technology and engineering or career and technical education program. In addition to showcasing instructional programs, a tech show allows students to demonstrate their professionalism and skills, practice public presentations, and interact…

  3. Measuring performance at trade shows

    DEFF Research Database (Denmark)

    Hansen, Kåre

    2004-01-01

    Trade shows is an increasingly important marketing activity to many companies, but current measures of trade show performance do not adequately capture dimensions important to exhibitors. Based on the marketing literature's outcome and behavior-based control system taxonomy, a model is built...... that captures a outcome-based sales dimension and four behavior-based dimensions (i.e. information-gathering, relationship building, image building, and motivation activities). A 16-item instrument is developed for assessing exhibitors perceptions of their trade show performance. The paper presents evidence...

  4. Leading the Way. Report of Employers Whose Companies and Employees Took Part in the Learning in Smaller Companies (LISC) Project.

    Science.gov (United States)

    Seagraves, Liz, Ed.

    This document is written by employers whose companies participated in the Learning in Smaller Companies (LISC) project, during which a university and two further education colleges created a number of work-based learning schemes for employers in small and medium-sized enterprises in Scotland. The foreword (Peter Swinson) discusses the importance…

  5. Tokyo Motor Show 2003; Tokyo Motor Show 2003

    Energy Technology Data Exchange (ETDEWEB)

    Joly, E.

    2004-01-01

    The text which follows present the different techniques exposed during the 37. Tokyo Motor Show. The report points out the great tendencies of developments of the Japanese automobile industry. The hybrid electric-powered vehicles or those equipped with fuel cells have been highlighted by the Japanese manufacturers which allow considerable budgets in the research of less polluting vehicles. The exposed models, although being all different according to the manufacturer, use always a hybrid system: fuel cell/battery. The manufacturers have stressed too on the intelligent systems for navigation and safety as well as on the design and comfort. (O.M.)

  6. Smaller than a gnat

    CERN Multimedia

    2006-01-01

    "CERN in Geneva is the largest research center for particle physics in the world; the Institute is a Mecca for scientists. Particle are projected into each other in gigantic ring accelerators to gain information from their reactions about the force and relations inside the elements. These experiments require high vacuum - Oerlikon Leybold Vacuum recently competed in a Eyropean call for bids for the Large Hadron Collider (LHC) and won the contract." (1,5 page)

  7. Making Microbiology Even Smaller!

    Science.gov (United States)

    Young, Linda Mull; Motz, Vicki Abrams

    2013-01-01

    We outline protocols for producing slant-minis (SLINIs) and mini-deeps (MEEPs) and examples of their use in simple microbiology experiments suitable for high school students. The principal benefits of these protocols are decreased cost associated with significantly reduced media use; easier, less expensive disposal of waste; and increased safety…

  8. Sharing Smaller Pies.

    Science.gov (United States)

    Bender, Tom

    This paper details the unfavorable predicament of the United States as a consequence of using much of its own non-renewable material and energy resources. As a consequence, the United States will soon be subject to the political and economic conditions imposed upon it by other nations. The United States must begin to implement adjustments to the…

  9. Making Microbiology Even Smaller!

    Science.gov (United States)

    Young, Linda Mull; Motz, Vicki Abrams

    2013-01-01

    We outline protocols for producing slant-minis (SLINIs) and mini-deeps (MEEPs) and examples of their use in simple microbiology experiments suitable for high school students. The principal benefits of these protocols are decreased cost associated with significantly reduced media use; easier, less expensive disposal of waste; and increased safety…

  10. Risk Aversion in Game Shows

    DEFF Research Database (Denmark)

    Andersen, Steffen; Lau, Morten I.; Rutström, E. Elisabet

    2008-01-01

    , and the dynamic nature of the task in most games. We consider the game shows Card Sharks, Jeopardy!, Lingo, and finally Deal Or No Deal. We provide a detailed case study of the analyses of Deal Or No Deal, since it is suitable for inference about risk attitudes and has attracted considerable attention....

  11. Phyllodes tumor showing intraductal growth.

    Science.gov (United States)

    Makidono, Akari; Tsunoda, Hiroko; Mori, Miki; Yagata, Hiroshi; Onoda, Yui; Kikuchi, Mari; Nozaki, Taiki; Saida, Yukihisa; Nakamura, Seigo; Suzuki, Koyu

    2013-07-01

    Phyllodes tumor of the breast is a rare fibroepithelial lesion and particularly uncommon in adolescent girls. It is thought to arise from the periductal rather than intralobular stroma. Usually, it is seen as a well-defined mass. Phyllodes tumor showing intraductal growth is extremely rare. Here we report a girl who has a phyllodes tumor with intraductal growth.

  12. Pembrolizumab Shows Promise for NSCLC.

    Science.gov (United States)

    2015-06-01

    Data from the KEYNOTE-001 trial show that pembrolizumab improves clinical outcomes for patients with advanced non-small cell lung cancer, and is well tolerated. PD-L1 expression in at least 50% of tumor cells correlated with improved efficacy.

  13. Create a Polarized Light Show.

    Science.gov (United States)

    Conrad, William H.

    1992-01-01

    Presents a lesson that introduces students to polarized light using a problem-solving approach. After illustrating the concept using a slinky and poster board with a vertical slot, students solve the problem of creating a polarized light show using Polya's problem-solving methods. (MDH)

  14. Reality show: um paradoxo nietzschiano

    Directory of Open Access Journals (Sweden)

    Ilana Feldman

    2011-01-01

    Full Text Available

    O fenômeno dos reality shows - e a subseqüente relação entre imagem e verdade - assenta-se sobre uma série de paradoxos. Tais paradoxos podem ser compreendidos à luz do pensamento do filósofo alemão Friedrich Nietzsche, que, através dos usos de formulações paradoxais, concebia a realidade como um mundo de pura aparência e a verdade como um acréscimo ficcional, como um efeito. A ficção é então tomada, na filosofia de Nietzsche, não em seu aspecto falsificante e desrealizador - como sempre pleiteou nossa tradição metafísica -, mas como condição necessária para que certa espécie de invenção possa operar como verdade. Sendo assim, a própria expressão reality show, através de sua formulação paradoxal, engendra explicitamente um mundo de pura aparência, em que a verdade, a parte reality da proposição, é da ordem do suplemento, daquilo que se acrescenta ficcionalmente - como um adjetivo - a show. O ornamento, nesse caso, passa a ocupar o lugar central, apontando para o efeito produzido: o efeito-de-verdade. Seguindo, então, o pensamento nietzschiano e sua atualização na contemporaneidade, investigaremos de que forma os televisivos “shows de realidade” operam paradoxalmente, em consonância com nossas paradoxais práticas culturais.

  15. Picasso on Show in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    A staff member of the National Picasso Museum of France checks one of the great Spanish artist Pablo Picasso’s works at the China Pavilion inside the site of the 2010 World Expo in Shanghai on October 12.Sixty-two priceless paintings and statues selected from the works of the renowned artist have been brought to the pavilion for an upcoming exhibition to premiere on October 18.Besides these representative masterpieces,50 valuable photographs showing the artist’s whole life will also be presented.The exhibition’s estimated value is 678 million euros ($934 million).It will be held until January 10,2012.

  16. Reality shows: uma abordagem psicossocial

    Directory of Open Access Journals (Sweden)

    Marília Pereira Bueno Millan

    Full Text Available Desde os primórdios da civilização, o ser humano mostra necessidade de representar cenicamente seus dramas pessoais e vicissitudes existenciais. O "reality show" é uma das versões pós-modernas da encenação da vida humana. Este artigo, por meio de uma pesquisa bibliográfica, analisa criticamente as relações existentes entre o "reality show" e aspectos psicossociais do comportamento humano. Conclui-se que tais programas televisivos são o retrato da contemporaneidade, ou seja, revelam a morte do sujeito, a fugacidade das experiências vividas, a desvalorização da história e o culto à imagem e à superficialidade. Por meio da sedução do espectador, mobilizam-se aspectos primitivos de seu psiquismo, fazendo com que ele se sinta narcisicamente poderoso e onipotente e se acredite dono do destino dos participantes do programa. Sugerem-se novos estudos que contribuam para a reflexão crítica e maior conscientização.

  17. "Medicine show." Alice in Doctorland.

    Science.gov (United States)

    1987-01-01

    This is an excerpt from the script of a 1939 play provided to the Institute of Social Medicine and Community Health by the Library of Congress Federal Theater Project Collection at George Mason University Library, Fairfax, Virginia, pages 2-1-8 thru 2-1-14. The Federal Theatre Project (FTP) was part of the New Deal program for the arts 1935-1939. Funded by the Works Progress Administration (WPA) its goal was to employ theater professionals from the relief rolls. A number of FTP plays deal with aspects of medicine and public health. Pageants, puppet shows and documentary plays celebrated progress in medical science while examining social controversies in medical services and the public health movement. "Medicine Show" sharply contrasts technological wonders with social backwardness. The play was rehearsed by the FTP but never opened because funding ended. A revised version ran on Broadway in 1940. The preceding comments are adapted from an excellent, well-illustrated review of five of these plays by Barabara Melosh: "The New Deal's Federal Theatre Project," Medical Heritage, Vol. 2, No. 1 (Jan/Feb 1986), pp. 36-47.

  18. From “Smaller is Stronger” to “Size-Independent Strength Plateau”: Towards Measuring the Ideal Strength of Iron

    KAUST Repository

    Han, Wei-Zhong

    2015-04-17

    The trend from “smaller is stronger” to “size-independent strength plateau” is observed in the compression of spherical iron nanoparticles. When the diameter of iron nanospheres is less than a critical value, the maximum contact pressure saturates at 10.7 GPa, corresponding to a local shear stress of ≈9.4 GPa, which is comparable to the theoretical shear strength of iron.

  19. Smaller splenium in children with nonverbal learning disability compared to controls, high-functioning autism and ADHD.

    Science.gov (United States)

    Fine, Jodene Goldenring; Musielak, Kayla A; Semrud-Clikeman, Margaret

    2014-01-01

    The current study investigated morphological differences in the corpus callosum in children ages 8 to 18 years old with nonverbal learning disability (NLD; n = 19), high-functioning autism (HFA; n = 23), predominantly inattentive ADHD (ADHD:PI; n = 23), and combined type ADHD (ADHD:C; n = 25), as well as those demonstrating typical development (n = 57). Midsagittal area of the corpus callosum and five midsagittal anterior-to-posterior corpus callosum segments were examined using magnetic resonance imaging. Controlling for midsagittal brain area and age, no group differences were found for total corpus callosum area. This finding indicates that higher functioning children on the autistic spectrum do not have smaller corpus callosi as has been found in previous research with heterogeneous samples. Following segmentation of the corpus callosum, the NLD group was observed to have significantly smaller splenia compared to all other groups. Smaller splenia in the NLD group was associated with lower WASI PIQ scores but not WASI VIQ scores. Children with HFA were observed to have larger midbody areas than children with NLD and neurotypically developing children. Children with HFA and NLD demonstrated behavioral symptoms of inattention and hyperactivity similar to the ADHD groups indicating that corpus callosum differences seen in the NLD and HFA groups are not related to these behaviors.

  20. Geoinformation Generalization by Aggregation

    Directory of Open Access Journals (Sweden)

    Tomislav Jogun

    2016-12-01

    Full Text Available Geoinformation generalization can be divided into model generalization and cartographic generalization. Model generalization is the supervised reduction of data in a model, while cartographic generalization is the reduction of the complexity of map content adapted to the map scale, and/or use by various generalization operators (procedures. The topic of this paper is the aggregation of geoinformation. Generally, aggregation is the joining of nearby, congenial objects, when the distance between them is smaller than the minimum sizes. Most researchers in geoinformation generalization have focused on line features. However, the appearance of web-maps with point features and choropleth maps has led to the development of concepts and algorithms for the generalization of point and polygonal features. This paper considers some previous theoretical premises and actual examples of aggregation for point, line and polygonal features. The algorithms for aggregation implemented in commercial and free GIS software were tested. In the conclusion, unresolved challenges that occur in dynamic cartographic visualizations and cases of unusual geometrical features are highlighted.

  1. Generalized Probability Functions

    Directory of Open Access Journals (Sweden)

    Alexandre Souto Martinez

    2009-01-01

    Full Text Available From the integration of nonsymmetrical hyperboles, a one-parameter generalization of the logarithmic function is obtained. Inverting this function, one obtains the generalized exponential function. Motivated by the mathematical curiosity, we show that these generalized functions are suitable to generalize some probability density functions (pdfs. A very reliable rank distribution can be conveniently described by the generalized exponential function. Finally, we turn the attention to the generalization of one- and two-tail stretched exponential functions. We obtain, as particular cases, the generalized error function, the Zipf-Mandelbrot pdf, the generalized Gaussian and Laplace pdf. Their cumulative functions and moments were also obtained analytically.

  2. Level and Contamination Assessment of Environmentally Sensitive Elements in Smaller than 100 μm Street Dust Particles from Xining, China

    Directory of Open Access Journals (Sweden)

    Ni Zhao

    2014-02-01

    Full Text Available Concentrations of the environmentally sensitive elements (ESEs As, Co, Cu, Mn, Ni, Pb, V and Zn in smaller than 100 μm street dust particles from Xining were measured using X-ray fluorescence spectrometry and their contamination levels were assessed based on enrichment factor (EF, geoaccumulation index (Igeo and pollution load index (PLI. The concentrations of As, Co, Cu, Mn, Ni, Pb, V and Zn in smaller than 100 μm street dust particles from Xining are 0.1–0.8, 2.7–10.9, 0.7–5.2, 0.3–1.1, 0.6–2.5, 1.2–11.1, 0.7–1.3 and 0.4–2.9 times the background values of Qinghai soil, respectively. The calculated EF and Igeo values reveal the order Co > Pb > Cu > Zn > V > Ni > Mn > As. The EF and Igeo values of Co, Cu, Pb and Zn are higher indicating that there is considerable pollution by these elements in smaller than 100 μm street dust particles, especially for Co. The EF and Igeo of Mn, Ni and V are lower and the assessment results indicate an absence of distinct Mn, Ni and V pollution in the studied samples. The mean value of PLIsite is 1.14, indicating a slightly pollution in the whole city of Xining. The order of PLIarea for the five tested districts is Center District (CD > East District (ED > West District (WD > North District (ND > South District (SD, showing that ESEs pollution in the South District is the lightest while it is the highest in the Central District.

  3. General Dentist

    Science.gov (United States)

    ... Some general dentists work in government health services, research programs, higher education, corporations and even the military. ?xml:namespace> What kind of procedures do general dentists provide? ?xml:namespace> Many general dentists are ...

  4. Global and regional associations of smaller cerebral gray and white matter volumes with gait in older people.

    Directory of Open Access Journals (Sweden)

    Michele L Callisaya

    Full Text Available BACKGROUND: Gait impairments increase with advancing age and can lead to falls and loss of independence. Brain atrophy also occurs in older age and may contribute to gait decline. We aimed to investigate global and regional relationships of cerebral gray and white matter volumes with gait speed, and its determinants step length and cadence, in older people. METHODS: In a population-based study, participants aged >60 years without Parkinson's disease or brain infarcts underwent magnetic resonance imaging and gait measurements using a computerized walkway. Linear regression was used to study associations of total gray and white matter volumes with gait, adjusting for each other, age, sex, height and white matter hyperintensity volume. Other covariates considered in analyses included weight and vascular disease history. Voxel-based morphometry was used to study regional relationships of gray and white matter with gait. RESULTS: There were 305 participants, mean age 71.4 (6.9 years, 54% male, mean gait speed 1.16 (0.22 m/s. Smaller total gray matter volume was independently associated with poorer gait speed (p = 0.001 and step length (p<0.001, but not cadence. Smaller volumes of cortical and subcortical gray matter in bilateral regions important for motor control, vision, perception and memory were independently associated with slower gait speed and shorter steps. No global or regional associations were observed between white matter volume and gait independent of gray matter volume, white matter hyperintensity volume and other covariates. CONCLUSION: Smaller gray matter volume in bilaterally distributed brain networks serving motor control was associated with slower gait speed and step length, but not cadence.

  5. Smaller Anterior Cruciate Ligament Diameter Is a Predictor of Subjects Prone to Ligament Injuries: An Ultrasound Study

    Directory of Open Access Journals (Sweden)

    Parag Suresh Mahajan

    2015-01-01

    Full Text Available Purpose. To test if diameter of normal anterior cruciate ligament (ACL can be measured by ultrasound (US, to see if there is a relationship between smaller ACL diameter and ACL injury, and to assess agreement between radiologists in measuring ACL diameter in cases and matched controls. Materials and Methods. In this ethics committee-approved study, maximum diameter of ACL near tibial insertion site was measured by static and dynamic US study in 25 normal contralateral knees of subjects who suffered noncontact ACL injury and in 25 matched control subjects. Results. ACL was visualized as a thick linear hypoechoic band inserted approximately 11 mm caudal to the tibial plateau and the intercondylar eminence. Maximum diameter of contralateral ACL near tibial insertion site among injured subjects was significantly smaller than in noninjured subjects (0.62 ± 0.07 cm versus 0.81 ± 0.06 cm; P<0.0001. In the regression analysis, the diameter of ACL near tibial insertion site was found significantly proportional to body weight and not significantly associated to height, gender, and age. Conclusion. Diameter of normal ACL near tibial insertion site can be measured by US and the maximum diameter is significantly smaller among subjects with noncontact ACL injury. US is a promising modality that can be used as an excellent screening test to detect subjects especially aspiring athletes prone to ACL injury. Very strong agreement was observed between radiologists in measuring ACL diameter.

  6. Why bacteria are smaller in the epilimnion than in the hypolimnion? A hypothesis comparing temperate and tropical lakes

    Directory of Open Access Journals (Sweden)

    Roberto Bertoni

    2012-01-01

    Full Text Available Bacterial size and morphology are controlled by several factors including predation, viral lysis, UV radiation, and inorganic nutrients. We observed that bacterial biovolume from the hypolimnion of two oligotrophic lakes is larger than that of bacteria living in the layer from surface to 20 m, roughly corresponding to the euphotic/epilimnetic zone. One lake is located in the temperate region at low altitude (Lake Maggiore, Northern Italy and the other in the tropical region at high altitude (Lake Alchichica, Mexico. The two lakes differ in oxygen, phosphorus and nitrogen concentrations and in the temperature of water column. If we consider the two lakes separately, we risk reducing the explanation of bacterial size variation in the water column to merely regional factors. Comparing the two lakes, can we gather a more general explanation for bacterial biovolume variation. The results showed that small bacteria dominate in the oxygenated, P-limited epilimnetic waters of both lakes, whereas larger cells are more typical of hypolimnetic waters where phosphorus and nitrogen are not limiting. Indeed, temperature per se cannot be invoked as an important factor explaining the different bacterial size in the two zones. Without excluding the top-down control mechanism of bacterial size, our data suggest that the average lower size of bacterial cells in the epilimnion of oligotrophic lakes is controlled by outcompetition over the larger cells at limiting nutrients.

  7. Bite my art to show your love

    OpenAIRE

    Kim, Hye yeon

    2012-01-01

    Two years ago, I came to the States for MFA program in UCSD. At first, I started making instructions for performance to communicate with people in my clumsy English, but it soon became my general process of working. In this show, I present a room surrounded by five video projections and drawings. They are documentation of performances concerning the balance of relationship. I performed two with Josh Aaron, other two with Josh Tonies, and one by myself. The performance done by myself reveals t...

  8. Pain in lambs castrated at 2 days using novel smaller and tighter rubber rings without and with local anaesthetic.

    Science.gov (United States)

    Molony, Vince; Kent, Joyce E; Viñuela-Fernández, Ignacio; Anderson, Claire; Dwyer, Cathy M

    2012-07-01

    Without effective pain relief, rubber ring castration of lambs is acutely painful and can also produce chronic pain. The potential of novel, smaller rubber rings to reduce this pain substantially has been investigated. Three groups of eight 2-3 day old lambs, were castrated either with conventional rubber rings (cRR), or novel smaller rubber rings without (nRR) and with local anaesthetic treatment (nRR+La). Behavioural responses and chronic lesions indicative of pain were compared. No major reductions in behavioural responses were produced by castration with nRRs compared with cRRs, but injection of local anaesthetic did reduce these responses significantly. Lambs in all groups developed chronic inflammatory lesions but behavioural evidence of chronic pain was rarely seen. After 28 days, 6/8 necrotic scrotums had been shed by nRR+La; 4/8 by nRR and 2/8 by cRR lambs. The dimensions of rubber rings on necrotic scrotums, suggest that cRRs contracted to their un-stretched size before being shed, whereas nRRs did not. It is concluded that neither of these rubber rings exerted sufficient pressure on trapped nerves to produce anaesthesia rapidly and this may be explained by the physical properties of the tissues at the neck of the scrotum which support the ring. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Two phosphoenolpyruvate carboxykinases coexist in the Crassulacean Acid Metabolism plant Ananas comosus. Isolation and characterization of the smaller 65 kDa form.

    Science.gov (United States)

    Martín, Mariana; Rius, Sebastián Pablo; Podestá, Florencio Esteban

    2011-06-01

    Two phosphoenolpyruvate carboxykinase (PEPCK, EC 4.1.1.49) isoforms of 74 and 65 kDa were found to coexist in vivo in pineapple leaves, a constitutive Crassulacean Acid Metabolism plant. The 65 kDa form was not the result of proteolytic cleavage of the larger form since extraction methods reported to prevent PEPCK proteolysis in other plant tissues failed to yield a single immunoreactive PEPCK polypeptide in leaf extracts. In this work, the smaller form of 65 kDa was purified to homogeneity and physically and kinetically characterized and showed parameters compatible with a fully active enzyme. The specific activity was nearly twice higher for decarboxylation of oxaloacetate when compared to carboxylation of phosphoenolpyruvate. Kinetic parameters fell within the range of those estimated for other plant PEPCKs. Its activity was affected by several metabolites, as shown by inhibition by 3-phosphoglycerate, citrate, malate, fructose-1,6-bisphosphate, l-asparagine and activation of the decarboxylating activity by succinate. A break in the Arrhenius plot at about 30°C indicates that PEPCK structure is responsive to changes in temperature. The results indicate that pineapple leaves contain two PEPCK forms. The biochemical characterization of the smaller isoform performed in this work suggests that it could participate in both carbon and nitrogen metabolism in vivo by acting as a decarboxylase.

  10. Initial basal cell carcinomas diagnosed in the National Campaign for Skin Cancer Prevention are smaller than those identified by the conventional medical referral system*

    Science.gov (United States)

    Wakiyama, Thweicyka Pinheiro; França, Maria Laura Marconi; Carvalho, Larissa Pierri; Marques, Mariangela Esther Alencar; Miot, Hélio Amante; Schmitt, Juliano Vilaverde

    2017-01-01

    BACKGROUND Basal cell carcinoma is the malignant tumor most often diagnosed in the National Campaign for Skin Cancer Prevention (NCSCP). Little is known about the profile of these lesions compared to the profile of lesions diagnosed by conventional routes of public dermatological care. OBJECTIVE To identify if basal cell carcinomas identified in prevention campaigns and referred to surgery are smaller than those routinely removed in a same medical institution. METHODS Cross-sectional study including tumors routed from 2011-2014 campaigns and 84 anatomopathological reports of outpatients. RESULTS The campaigns identified 223 individuals with suspicious lesions among 2,531 examinations (9%), with 116 basal cell carcinomas removed. Anatomopathological examinations revealed that the primary lesions identified in the national campaigns were smaller than those referred to surgery by the conventional routes of public health care (28 [13-50] x 38 [20-113] mm2, p <0.01). On the other hand, after a mean follow-up of 15.6 ± 10.3 months, 31% of cases identified in campaigns showed new basal cell carcinoma lesions. STUDY LIMITATIONS Retrospective study and inaccuracies in the measurements of the lesions. CONCLUSIONS The NCSCP promotes an earlier treatment of basal cell carcinomas compared to patients referred to surgery by the conventional routes of public health care, which can result in lower morbidity rates and better prognosis. PMID:28225952

  11. Organizational resilience: Sustained institutional effectiveness among smaller, private, non-profit US higher education institutions experiencing organizational decline.

    Science.gov (United States)

    Moran, Kenneth A

    2016-06-04

    Recent changes in the United States (US) economy have radically disrupted revenue generation among many institutions within higher education within the US. Chief among these disruptions has been fallout associated with the financial crisis of 2008-2009, which triggered a change in the US higher education environment from a period of relative munificence to a prolonged period of scarcity. The hardest hit by this disruption have been smaller, less wealthy institutions which tend to lack the necessary reserves to financially weather the economic storm. Interestingly, a review of institutional effectiveness among these institutions revealed that while many are struggling, some institutions have found ways to not only successfully cope with the impact of declining revenue, but have been able to capitalize on the disruption and thrive. Organizational response is an important factor in successfully coping with conditions of organizational decline. The study examined the impacts of organizational response on institutional effectiveness among higher education institutions experiencing organizational decline. The study's research question asked why some US higher educational institutions are more resilient at coping with organizational decline than other institutions operating within the same segment of the higher education sector. More specifically, what role does organizational resilience have in helping smaller, private non-profit institutions cope and remain effective during organizational decline? A total of 141 US smaller, private non-profit higher educational institutions participated in the study; specifically, the study included responses from participant institutions' key administrators. 60-item survey evaluated administrator responses corresponding to organizational response and institutional effectiveness. Factor analysis was used to specify the underlying structures of rigidity response, resilience response, and institutional effectiveness. Multiple regression

  12. Application of Periapse Maps for the Design of Trajectories Near the Smaller Primary in Multi-Body Regimes

    Directory of Open Access Journals (Sweden)

    Kathleen C. Howell

    2012-01-01

    Full Text Available The success of the Genesis spacecraft, as well as the current Artemis mission, continue to generate interest in expanding the trajectory options for future science and exploration goals throughout the solar system. Incorporating multi-body dynamics into the preliminary design can potentially offer flexibility and influence the maneuver costs to achieve certain objectives. In the current analysis, attention is focused on the development and application of design tools to facilitate preliminary trajectory design in a multi-body environment. Within the context of the circular restricted three-body problem, the evolution of a trajectory in the vicinity of the smaller primary is investigated. Introduced previously, periapse Poincaré maps have emerged as a valuable resource to predict both short- and long-term trajectory behaviors. By characterizing the trajectories in terms of radius and periapse orientation relative to the 1-2 line, useful trajectories with a particular set of desired characteristics can be identified and computed.

  13. The Transit Light Curve Project. IX. Evidence for a Smaller Radius of the Exoplanet XO-3b

    CERN Document Server

    Winn, Joshua N; Torres, Guillermo; McCullough, Peter; Johns-Krull, Christopher M; Latham, David W; Shporer, Avi; Mazeh, Tsevi; Garcia-Melendo, Enrique; Foote, Cindy; Esquerdo, Gil; Everett, Mark

    2008-01-01

    We present photometry of 13 transits of XO-3b, a massive transiting planet on an eccentric orbit. Previous data led to two inconsistent estimates of the planetary radius. Our data strongly favor the smaller radius, with increased precision: R_p = 1.217 +/- 0.073 R_Jup. A conflict remains between the mean stellar density determined from the light curve, and the stellar surface gravity determined from the shapes of spectral lines. We argue the light curve should take precedence, and revise the system parameters accordingly. The planetary radius is about 1 sigma larger than the theoretical radius for a hydrogen-helium planet of the given mass and insolation. To help in planning future observations, we provide refined transit and occultation ephemerides.

  14. Smaller kidney size at birth in South Asians: findings from the Born in Bradford birth cohort study.

    Science.gov (United States)

    Roderick, Paul J; Jeffrey, Robin F; Yuen, Ho M; Godfrey, Keith M; West, Jane; Wright, John

    2016-03-01

    Rates of advanced chronic kidney disease and renal replacement therapy are higher in South Asian than in white British populations. Low birth weight is also more frequent in South Asian populations and has been associated with increased risks of kidney disease, perhaps due to a reduced nephron endowment. Using ultrasound scans at 34 weeks of gestation, we measured fetal kidney dimensions (transverse and anteroposterior diameters, length and circumference) and derived volume in a random sample of 872 white British and 715 South Asian participants in the Born in Bradford cohort study. Kidney measurements were compared between ethnic groups. Birth weight for gestational age at 40 weeks was 200 g less in South Asian babies compared with white British babies. The mean kidney volume for gestational age was 16% lower in South Asian than in white British babies [8.79 versus 10.45 cm(3), difference 1.66 cm(3) (95% confidence interval 1.40-1.93, P < 0.001)]. The difference was robust after adjustment for maternal age, socio-economic factors, marital status, body mass index, smoking and alcohol use in pregnancy, parity, baby's gender and birth weight for gestational age [adjusted difference 1.38 cm(3) (0.97-1.84), P < 0.001]. There were smaller reductions in other fetal measures. South Asian babies have smaller kidneys compared with white British babies, even after adjusting for potential confounders including birth weight. This finding may contribute to increased risks of adult kidney disease in South Asian populations. © The Author 2015. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

  15. Stone Matrix Asphalt (SMA is a gap-graded mix that is gaining popularity worldwide. Generally, gap graded mixes are thought to be weak in fatigue resistance. In this study, cellulose fibers were pre-blended in PG64-22 binder with fiber proportions of 0.2%, 0.4%, 0.6%, 0.8% and 1.0% by weight of aggregates. The fiber-modified binder showed improved rheological properties and showed that the PG64-22 binder can be modified and raised to PG70-22 grade. The cellulose oil palm fiber (COPF was found to improve the diameteral fatigue performance of SMA design mix. The fatigue life increased to a maximum at a fiber content of about 0.6%, whilst the tensile stress and stiffness also showed a similar trend in performance. The initial strains of the mix were lowest at a fiber content of 0.6%.

    Directory of Open Access Journals (Sweden)

    Ratnasamy Muniandy

    2006-01-01

    Full Text Available Stone Matrix Asphalt (SMA is a gap-graded mix that is gaining popularity worldwide. Generally, gap graded mixes are thought to be weak in fatigue resistance. In this study, cellulose fibers were pre-blended in PG64-22 binder with fiber proportions of 0.2%, 0.4%, 0.6%, 0.8% and 1.0% by weight of aggregates. The fiber-modified binder showed improved rheological properties and showed that the PG64-22 binder can be modified and raised to PG70-22 grade. The cellulose oil palm fiber (COPF was found to improve the diameteral fatigue performance of SMA design mix. The fatigue life increased to a maximum at a fiber content of about 0.6%, whilst the tensile stress and stiffness also showed a similar trend in performance. The initial strains of the mix were lowest at a fiber content of 0.6%.

  16. Prevalence of mastitis and brucellosis in cattle in Awassa and the peri-urban areas of two smaller towns.

    Science.gov (United States)

    Abebe, G; Ike, A C; Siegmund-Schultze, M; Mané-Bielfeldt, A; Valle Zárate, A

    2010-08-01

    The prevalence of mastitis and brucellosis in urban and peri-urban settings was studied in Awassa and two smaller nearby towns in southern Ethiopia, because milk-born diseases are causing a risk for human health, besides direct impacts on animal production. Mastitis was investigated by examining 80 cows (320 udder quarters) using California mastitis test (CMT) and somatic cell count (SCC). The prevalence of brucellosis was assessed by sampling 177 cattle in Awassa and its peri-urban areas using serological methods. Logistic regression was used to analyse risk factors associated with mastitis. Prevalence of clinical mastitis on quarter level was 0.9%, and 1.9% of quarters were non-functional or blocked. Prevalence of sub-clinical mastitis at quarter level in urban and peri-urban areas was significantly different (P CMT (42.5%) was close to the percentage-positive detected by SCC (41.2%). Prevalence of brucellosis was 3.9% in the peri-urban area, while no brucellosis cases were detected in Awassa. More frequent use of artificial insemination in the urban than in peri-urban area might have contributed to the absence of brucellosis in the urban location. The extent of mastitis is, however, a threat to the dairy enterprise in and around Awassa. Pasteurization of milk and milk products is indicated in some parts of the area because of the danger of brucellosis.

  17. Higher media multi-tasking activity is associated with smaller gray-matter density in the anterior cingulate cortex.

    Directory of Open Access Journals (Sweden)

    Kep Kee Loh

    Full Text Available Media multitasking, or the concurrent consumption of multiple media forms, is increasingly prevalent in today's society and has been associated with negative psychosocial and cognitive impacts. Individuals who engage in heavier media-multitasking are found to perform worse on cognitive control tasks and exhibit more socio-emotional difficulties. However, the neural processes associated with media multi-tasking remain unexplored. The present study investigated relationships between media multitasking activity and brain structure. Research has demonstrated that brain structure can be altered upon prolonged exposure to novel environments and experience. Thus, we expected differential engagements in media multitasking to correlate with brain structure variability. This was confirmed via Voxel-Based Morphometry (VBM analyses: Individuals with higher Media Multitasking Index (MMI scores had smaller gray matter density in the anterior cingulate cortex (ACC. Functional connectivity between this ACC region and the precuneus was negatively associated with MMI. Our findings suggest a possible structural correlate for the observed decreased cognitive control performance and socio-emotional regulation in heavy media-multitaskers. While the cross-sectional nature of our study does not allow us to specify the direction of causality, our results brought to light novel associations between individual media multitasking behaviors and ACC structure differences.

  18. Using a smaller dining plate does not suppress food intake from a buffet lunch meal in overweight, unrestrained women.

    Science.gov (United States)

    Yip, Wilson; Wiessing, Katy R; Budgett, Stephanie; Poppitt, Sally D

    2013-10-01

    The aim of the study was to determine whether plate size affects ad libitum energy intake (EI) at a buffet-style lunch in overweight, yet unrestrained women. Twenty overweight/obese (BMI=25-40 kg/m(2)) women attended two study visits, and were randomly assigned to small (19.5 cm) or large (26.5 cm) diameter plate size at a free choice lunch meal. At 9 am participants were given a small (0.5 MJ) breakfast, followed at 12 noon by the lunch meal from which they ate ad lib until comfortably full. Mean (SEM) EI at lunch was 3975 (239)kJ and 3901 (249) kJ respectively for small and large plate size. There was no detectable difference in EI between the two plate sizes (P>0.05). When in a raised state of hunger and offered a palatable buffet meal, altering the diameter of the dining plate onto which food was self-served did not significantly alter ad lib EI. We conclude there was no evidence that a smaller plate suppressed EI in a group of unrestrained, overweight women encouraged to eat to appetite from a wide choice of items. Whether plate size is a useful cue for portion size, and hence control of EI, in individuals actively restricting intake however remains possible, and requires investigation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Bubbling bed catalytic hydropyrolysis process utilizing larger catalyst particles and smaller biomass particles featuring an anti-slugging reactor

    Science.gov (United States)

    Marker, Terry L; Felix, Larry G; Linck, Martin B; Roberts, Michael J

    2014-09-23

    This invention relates to a process for thermochemically transforming biomass or other oxygenated feedstocks into high quality liquid hydrocarbon fuels. In particular, a catalytic hydropyrolysis reactor, containing a deep bed of fluidized catalyst particles is utilized to accept particles of biomass or other oxygenated feedstocks that are significantly smaller than the particles of catalyst in the fluidized bed. The reactor features an insert or other structure disposed within the reactor vessel that inhibits slugging of the bed and thereby minimizes attrition of the catalyst. Within the bed, the biomass feedstock is converted into a vapor-phase product, containing hydrocarbon molecules and other process vapors, and an entrained solid char product, which is separated from the vapor stream after the vapor stream has been exhausted from the top of the reactor. When the product vapor stream is cooled to ambient temperatures, a significant proportion of the hydrocarbons in the product vapor stream can be recovered as a liquid stream of hydrophobic hydrocarbons, with properties consistent with those of gasoline, kerosene, and diesel fuel. Separate streams of gasoline, kerosene, and diesel fuel may also be obtained, either via selective condensation of each type of fuel, or via later distillation of the combined hydrocarbon liquid.

  20. Large males have a mating advantage in a species of darter with smaller, allopaternal males Etheostoma olmstedi

    Directory of Open Access Journals (Sweden)

    Kelly A. STIVER,Suzanne H. ALONZO

    2010-02-01

    Full Text Available Theory suggests that males that are larger than their competitors may have increased mating success, due to both greater competitive ability and increased attractiveness to females. We examined how male mating success varies with male size in the tessellated darter Etheostoma olmstedi. Previous work has shown that large males tend to move around and breed in vacant breeding sites, and consequently provide less care for their eggs, while smaller individuals can be allopaternal, caring for the eggs of other males as well as for their own. We studied female egg deposition in a natural breeding population using artificial breeding sites and in the laboratory, where female choice of spawning site was restricted to two breeding sites tended by two males of different sizes. In both the field and the laboratory, nests tended by larger males were more likely to receive new eggs. Additionally, the mean size of males associated with a nest was positively correlated with both the maximum coverage of eggs at the nest and the number of times new eggs were deposited. We discuss how the increased mating success of larger males, despite their decreased parental care, may help explain allopaternal care in this species [Current Zoology 56 (1: 1–5 2010].

  1. Generalized product

    OpenAIRE

    Greco,Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  2. Generalized product

    OpenAIRE

    Greco, Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  3. SMALLER FOOTPRINT DRILLING SYSTEM FOR DEEP AND HARD ROCK ENVIRONMENTS; FEASIBILITY OF ULTRA-HIGH SPEED DIAMOND DRILLING

    Energy Technology Data Exchange (ETDEWEB)

    Alan Black; Arnis Judzis

    2004-10-01

    The two phase program addresses long-term developments in deep well and hard rock drilling. TerraTek believes that significant improvements in drilling deep hard rock will be obtained by applying ultra-high (greater than 10,000 rpm) rotational speeds. The work includes a feasibility of concept research effort aimed at development and test results that will ultimately result in the ability to reliably drill ''faster and deeper'' possibly with rigs having a smaller footprint to be more mobile. The principle focus is on demonstration testing of diamond bits rotating at speeds in excess of 10,000 rpm to achieve high rate of penetration rock cutting with substantially lower inputs of energy and loads. The project draws on TerraTek results submitted to NASA's ''Drilling on Mars'' program. The objective of that program was to demonstrate miniaturization of a robust and mobile drilling system that expends small amounts of energy. TerraTek successfully tested ultrahigh speed ({approx}40,000 rpm) small kerf diamond coring. Adaptation to the oilfield will require innovative bit designs for full hole drilling or continuous coring and the eventual development of downhole ultra-high speed drives. For domestic operations involving hard rock and deep oil and gas plays, improvements in penetration rates is an opportunity to reduce well costs and make viable certain field developments. An estimate of North American hard rock drilling costs is in excess of $1,200 MM. Thus potential savings of $200 MM to $600 MM are possible if drilling rates are doubled [assuming bit life is reasonable]. The net result for operators is improved profit margin as well as an improved position on reserves. The significance of the ''ultra-high rotary speed drilling system'' is the ability to drill into rock at very low weights on bit and possibly lower energy levels. The drilling and coring industry today does not practice this technology

  4. SMALLER FOOTPRINT DRILLING SYSTEM FOR DEEP AND HARD ROCK ENVIRONMENTS; FEASIBILITY OF ULTRA-HIGH SPEED DIAMOND DRILLING

    Energy Technology Data Exchange (ETDEWEB)

    Alan Black; Arnis Judzis

    2004-10-01

    The two phase program addresses long-term developments in deep well and hard rock drilling. TerraTek believes that significant improvements in drilling deep hard rock will be obtained by applying ultra-high (greater than 10,000 rpm) rotational speeds. The work includes a feasibility of concept research effort aimed at development and test results that will ultimately result in the ability to reliably drill ''faster and deeper'' possibly with rigs having a smaller footprint to be more mobile. The principle focus is on demonstration testing of diamond bits rotating at speeds in excess of 10,000 rpm to achieve high rate of penetration rock cutting with substantially lower inputs of energy and loads. The project draws on TerraTek results submitted to NASA's ''Drilling on Mars'' program. The objective of that program was to demonstrate miniaturization of a robust and mobile drilling system that expends small amounts of energy. TerraTek successfully tested ultrahigh speed ({approx}40,000 rpm) small kerf diamond coring. Adaptation to the oilfield will require innovative bit designs for full hole drilling or continuous coring and the eventual development of downhole ultra-high speed drives. For domestic operations involving hard rock and deep oil and gas plays, improvements in penetration rates is an opportunity to reduce well costs and make viable certain field developments. An estimate of North American hard rock drilling costs is in excess of $1,200 MM. Thus potential savings of $200 MM to $600 MM are possible if drilling rates are doubled [assuming bit life is reasonable]. The net result for operators is improved profit margin as well as an improved position on reserves. The significance of the ''ultra-high rotary speed drilling system'' is the ability to drill into rock at very low weights on bit and possibly lower energy levels. The drilling and coring industry today does not practice this technology

  5. Theoretical analysis of aqueous solutions of mixed strong electrolytes by a smaller-ion shell electrostatic model.

    Science.gov (United States)

    Fraenkel, Dan

    2014-02-07

    In spite of the great importance of mixed electrolytes in science and technology, no compelling theoretical explanation has been offered yet for the thermodynamic behavior of such systems, such as their deviation from ideality and the variation of their excess functions with ionic composition and concentration. Using the newly introduced Smaller-ion Shell treatment - an extension of the Debye-Hückel theory to ions of dissimilar size (hence DH-SiS) - simple analytic mathematical expressions can be derived for the mean and single-ion activity coefficients of binary electrolyte components of ternary ionic systems. Such expressions are based on modifying the parallel DH-SiS equations for pure binary ionic systems, by adding to the three ion-size parameters - a (of counterions), b+ (of positive coions), and b- (of negative coions) - a fourth parameter. For the (+ + -) system, this is "b++," the contact distance between non-coion cations. b++ is derived from fits with experiment and, like the other b's, is constant at varying ion concentration and combination. Four case studies are presented: (1) HCl-NaCl-H2O, (2) HCl-NH4Cl-H2O, (3) (0.01 M HX)-MX-H2O with X = Cl, Br, and with M = Li, Na, K, Cs, and (4) HCl-MCln-H2O with n = 2, M = Sr, Ba; and n = 3, M = Al, Ce. In all cases, theory is fully consistent with experiment when using a of the measured binary electrolyte as the sole fitting parameter. DH-SiS is thus shown to explain known "mysteries" in the behavior of ternary electrolytes, including Harned rule, and to adequately predict the pH of acid solutions in which ionized salts are present at different concentrations.

  6. 47 CFR 1.701 - Show cause orders.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Show cause orders. 1.701 Section 1.701..., and Reports Involving Common Carriers General § 1.701 Show cause orders. (a) The Commission may... order to show cause. The order shall contain a statement of the particulars and matters concerning...

  7. General relativity from three-forms in seven dimensions

    Science.gov (United States)

    Krasnov, Kirill

    2017-09-01

    We consider a certain theory of 3-forms in 7 dimensions, and study its dimensional reduction to 4D, compactifying the 7-dimensional manifold on the 3-sphere of a fixed radius. We show that the resulting 4D theory is (Riemannian) General Relativity (GR) in Plebanski formulation, modulo corrections that are negligible for curvatures smaller than Planckian. Possibly the most interesting point of this construction is that the dimensionally reduced theory is GR with a non-zero cosmological constant, and the value of the cosmological constant is directly related to the size of S3. Realistic values of Λ correspond to S3 of Planck size.

  8. General Relativity from Three-Forms in Seven Dimensions

    CERN Document Server

    Krasnov, Kirill

    2016-01-01

    We consider a certain theory of 3-forms in 7 dimensions, and study its dimensional reduction to 4D, compactifying the 7-dimensional manifold on the 3-sphere of a fixed radius. We show that the resulting 4D theory is General Relativity (GR) in Plebanski formulation, modulo corrections that are negligible for curvatures smaller than Planckian. Possibly the most interesting point of this construction is that the dimensionally reduced theory is GR with a non-zero cosmological constant, and the value of the cosmological constant is directly related to the size of S^3. Realistic values of Lambda correspond to S^3 of Planck size.

  9. General Conformity

    Science.gov (United States)

    The General Conformity requirements ensure that the actions taken by federal agencies in nonattainment and maintenance areas do not interfere with a state’s plans to meet national standards for air quality.

  10. General Anesthesia

    Science.gov (United States)

    ... unconscious and unable to feel pain during medical procedures. General anesthesia usually uses a combination of intravenous drugs ... 1998-2017 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.

  11. Show Horse Welfare: Horse Show Competitors' Understanding, Awareness, and Perceptions of Equine Welfare.

    Science.gov (United States)

    Voigt, Melissa A; Hiney, Kristina; Richardson, Jennifer C; Waite, Karen; Borron, Abigail; Brady, Colleen M

    2016-01-01

    The purpose of this study was to gain a better understanding of stock-type horse show competitors' understanding of welfare and level of concern for stock-type show horses' welfare. Data were collected through an online questionnaire that included questions relating to (a) interest and general understanding of horse welfare, (b) welfare concerns of the horse show industry and specifically the stock-type horse show industry, (c) decision-making influences, and (d) level of empathic characteristics. The majority of respondents indicated they agree or strongly agree that physical metrics should be a factor when assessing horse welfare, while fewer agreed that behavioral and mental metrics should be a factor. Respondent empathy levels were moderate to high and were positively correlated with the belief that mental and behavioral metrics should be a factor in assessing horse welfare. Respondents indicated the inhumane practices that most often occur at stock-type shows include excessive jerking on reins, excessive spurring, and induced excessive unnatural movement. Additionally, respondents indicated association rules, hired trainers, and hired riding instructors are the most influential regarding the decisions they make related to their horses' care and treatment.

  12. Hydrogeology, Regional aquifer boundaries, Published in 2002, Smaller than 1:100000 scale, NC DENR / Div. of Water Resources / Ground Water Management Section.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Hydrogeology dataset, published at Smaller than 1:100000 scale, was produced all or in part from Field Observation information as of 2002. It is described as...

  13. Road and Street Centerlines, Berrien Road Centerlines, Published in 2004, Smaller than 1:100000 scale, Southeast Georgia Regional Development Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — , published at Smaller than 1:100000 scale, was produced all or in part from Field Survey/GPS information as of 2004. It is described as 'Berrien Road Centerlines'....

  14. Road and Street Centerlines, Brantley Road Centerlines, Published in 2003, Smaller than 1:100000 scale, Southeast Georgia Regional Development Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — , published at Smaller than 1:100000 scale, was produced all or in part from Field Survey/GPS information as of 2003. It is described as 'Brantley Road Centerlines'....

  15. Hydrography, Artificial Drainage,Lakes,Ponds,Rivers,Streams, Published in unknown, Smaller than 1:100000 scale, Adroitec information systems Ltd..

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Hydrography dataset, published at Smaller than 1:100000 scale, was produced all or in part from Hardcopy Maps information as of unknown. It is described as...

  16. Aerial Photography and Imagery, Ortho-Corrected, 2006 NAIPs for all counties we serve., Published in 2006, Smaller than 1:100000 scale, Prairie Land Electric COOP, Inc..

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Aerial Photography and Imagery, Ortho-Corrected dataset, published at Smaller than 1:100000 scale, was produced all or in part from Orthoimagery information as...

  17. Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: “Herniated” HDL, a common feature in diabetes

    Science.gov (United States)

    Amigó, Núria; Mallol, Roger; Heras, Mercedes; Martínez-Hervás, Sergio; Blanco-Vaca, Francisco; Escolà-Gil, Joan Carles; Plana, Núria; Yanes, Óscar; Masana, Lluís; Correig, Xavier

    2016-01-01

    Recent studies have shown that pharmacological increases in HDL cholesterol concentrations do not necessarily translate into clinical benefits for patients, raising concerns about its predictive value for cardiovascular events. Here we hypothesize that the size-modulated lipid distribution within HDL particles is compromised in metabolic disorders that have abnormal HDL particle sizes, such as type 2 diabetes mellitus (DM2). By using NMR spectroscopy combined with a biochemical volumetric model we determined the size and spatial lipid distribution of HDL subclasses in a cohort of 26 controls and 29 DM2 patients before and after two drug treatments, one with niacin plus laropiprant and another with fenofibrate as an add-on to simvastatin. We further characterized the HDL surface properties using atomic force microscopy and fluorescent probes to show an abnormal lipid distribution within smaller HDL particles, a subclass particularly enriched in the DM2 patients. The reduction in the size, force cholesterol esters and triglycerides to emerge from the HDL core to the surface, making the outer surface of HDL more hydrophobic. Interestingly, pharmacological interventions had no effect on this undesired configuration, which may explain the lack of clinical benefits in DM2 subjects. PMID:26778677

  18. Generalized polygons

    CERN Document Server

    Van Maldeghem, Hendrik

    1998-01-01

    Generalized Polygons is the first book to cover, in a coherent manner, the theory of polygons from scratch. In particular, it fills elementary gaps in the literature and gives an up-to-date account of current research in this area, including most proofs, which are often unified and streamlined in comparison to the versions generally known. Generalized Polygons will be welcomed both by the student seeking an introduction to the subject as well as the researcher who will value the work as a reference. In particular, it will be of great value for specialists working in the field of generalized polygons (which are, incidentally, the rank 2 Tits-buildings) or in fields directly related to Tits-buildings, incidence geometry and finite geometry. The approach taken in the book is of geometric nature, but algebraic results are included and proven (in a geometric way!). A noteworthy feature is that the book unifies and generalizes notions, definitions and results that exist for quadrangles, hexagons, octagons - in the ...

  19. On the second weight of generalized Reed-Muller codes

    DEFF Research Database (Denmark)

    Geil, Hans Olav

    2008-01-01

    Not much is known about theweight distribution of the generalized Reed-Muller code RMq (s,m) when q > 2, s > 2 and m ≥ 2. Even the second weight is only known for values of s being smaller than or equal to q/2. In this paper we establish the second weight for values of s being smaller than q. For...

  20. General Relativity

    CERN Document Server

    Canuto, V

    2015-01-01

    This is an English translation of the Italian version of an encyclopedia chapter that appeared in the Italian Encyclopedia of the Physical Sciences, edited by Bruno Bertotti (1994). Following requests from colleagues we have decided to make it available to a more general readership. We present the motivation for constructing General Relativity, provide a short discussion of tensor algebra, and follow the set up of Einstein equations. We discuss briefly the initial value problem, the linear approximation and how should non gravitational physics be described in curved spacetime.

  1. Colonies of Bumble Bees (Bombus impatiens Produce Fewer Workers, Less Bee Biomass, and Have Smaller Mother Queens Following Fungicide Exposure

    Directory of Open Access Journals (Sweden)

    Olivia M. Bernauer

    2015-06-01

    Full Text Available Bees provide vital pollination services to the majority of flowering plants in both natural and agricultural systems. Unfortunately, both native and managed bee populations are experiencing declines, threatening the persistence of these plants and crops. Agricultural chemicals are one possible culprit contributing to bee declines. Even fungicides, generally considered safe for bees, have been shown to disrupt honey bee development and impair bumble bee behavior. Little is known, however, how fungicides may affect bumble bee colony growth. We conducted a controlled cage study to determine the effects of fungicide exposure on colonies of a native bumble bee species (Bombus impatiens. Colonies of B. impatiens were exposed to flowers treated with field-relevant levels of the fungicide chlorothalonil over the course of one month. Colony success was assessed by the number and biomass of larvae, pupae, and adult bumble bees. Bumble bee colonies exposed to fungicide produced fewer workers, lower total bee biomass, and had lighter mother queens than control colonies. Our results suggest that fungicides negatively affect the colony success of a native bumble bee species and that the use of fungicides during bloom has the potential to severely impact the success of native bumble bee populations foraging in agroecosystems.

  2. General Assembly

    CERN Multimedia

    Staff Association

    2016-01-01

    5th April, 2016 – Ordinary General Assembly of the Staff Association! In the first semester of each year, the Staff Association (SA) invites its members to attend and participate in the Ordinary General Assembly (OGA). This year the OGA will be held on Tuesday, April 5th 2016 from 11:00 to 12:00 in BE Auditorium, Meyrin (6-2-024). During the Ordinary General Assembly, the activity and financial reports of the SA are presented and submitted for approval to the members. This is the occasion to get a global view on the activities of the SA, its financial management, and an opportunity to express one’s opinion, including taking part in the votes. Other points are listed on the agenda, as proposed by the Staff Council. Who can vote? Only “ordinary” members (MPE) of the SA can vote. Associated members (MPA) of the SA and/or affiliated pensioners have a right to vote on those topics that are of direct interest to them. Who can give his/her opinion? The Ordinary General Asse...

  3. General discussion

    NARCIS (Netherlands)

    Jagers op Akkerhuis, Gerard A.J.M.

    2016-01-01

    The general discussion focuses on some aspects that are of overarching relevance for all the preceding chapters. The fi rst subject that is discussed is the relationship between systems theory and the philosophy of science. After a short summary of the principles of system science and the

  4. Generale preventie

    NARCIS (Netherlands)

    1949-01-01

    In part I of this study a survey has veen given of what Dutch authors have written since 1870, when capital punishment was abolished, on subjects concerning the general preventive effect of punishment. This historical survey ends where, during the years 1940-1945, under the stress of the occupation

  5. 41 CFR 60-300.64 - Show cause notices.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Show cause notices. 60... VETERANS General Enforcement and Complaint Procedures § 60-300.64 Show cause notices. When the Deputy Assistant Secretary has reasonable cause to believe that the contractor has violated the Act or this...

  6. 41 CFR 60-250.64 - Show cause notices.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Show cause notices. 60... VETERANS General Enforcement and Complaint Procedures § 60-250.64 Show cause notices. When the Deputy Assistant Secretary has reasonable cause to believe that the contractor has violated the Act or this...

  7. 41 CFR 60-741.64 - Show cause notices.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Show cause notices. 60... INDIVIDUALS WITH DISABILITIES General Enforcement and Complaint Procedures § 60-741.64 Show cause notices. When the Deputy Assistant Secretary has reasonable cause to believe that the contractor has...

  8. Longitudinal peak strain detects a smaller risk area than visual assessment of wall motion in acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Brudin Lars

    2010-01-01

    Full Text Available Abstract Background Opening of an occluded infarct related artery reduces infarct size and improves survival in acute ST-elevation myocardial infarction (STEMI. In this study we performed tissue Doppler analysis (peak strain, displacement, mitral annular movement (MAM and compared with visual assessment for the study of the correlation of measurements of global, regional and segmental function with final infarct size and transmurality. In addition, myocardial risk area was determined and a prediction sought for the development of infarct transmurality ≥50%. Methods Twenty six patients with STEMI submitted for primary percutaneous coronary intervention (PCI were examined with echocardiography on the catheterization table. Four to eight weeks later repeat echocardiography was performed for reassessment of function and magnetic resonance imaging for the determination of final infarct size and transmurality. Results On a global level, wall motion score index (WMSI, ejection fraction (EF, strain, and displacement all showed significant differences (p ≤ 0.001, p ≤ 0.001, p ≤ 0.001 and p = 0.03 between the two study visits, but MAM did not (p = 0.17. On all levels (global, regional and segmental and both pre- and post PCI, WMSI showed a higher correlation with scar transmurality compared to strain. We found that both strain and WMSI predicted the development of scar transmurality ≥50%, but strain added no significant information to that obtained with WMSI in a logistic regression analysis. Conclusions In patients with acute STEMI, WMSI, EF, strain, and displacement showed significant changes between the pre- and post PCI exam. In a ROC-analysis, strain had 64% sensitivity at 80% specificity and WMSI around 90% sensitivity at 80% specificity for the detection of scar with transmurality ≥50% at follow-up.

  9. [General psychotherapy].

    Science.gov (United States)

    Vymetal, J

    2003-01-01

    Nowadays a theoretical psychotherapeutical thinking develops from the eclectic practice and uses particularly the research of the effective factors of the therapy. Best they can be characterized as differentiate, synthetic, integrative and exceeding other approaches. The development in question goes on with attempts of creating a general model of the psychotherapy that could be a basis for models of special psychotherapies. The aim of such a model is to describe all that is present as important factor for inducing a desirable change of a human in all psychotherapeutical approaches. Among general models we can mention the generic model of D. E. Orlinski and K. I. Howard, Grawe's cube (the author is K. Grawe) and the equation of the psychotherapy.

  10. Generalized polygons

    CERN Document Server

    Maldeghem, Hendrik

    1998-01-01

    This book is intended to be an introduction to the fascinating theory ofgeneralized polygons for both the graduate student and the specialized researcher in the field. It gathers together a lot of basic properties (some of which are usually referred to in research papers as belonging to folklore) and very recent and sometimes deep results. I have chosen a fairly strict geometrical approach, which requires some knowledge of basic projective geometry. Yet, it enables one to prove some typically group-theoretical results such as the determination of the automorphism groups of certain Moufang polygons. As such, some basic group-theoretical knowledge is required of the reader. The notion of a generalized polygon is a relatively recent one. But it is one of the most important concepts in incidence geometry. Generalized polygons are the building bricks of Tits buildings. They are the prototypes and precursors of more general geometries such as partial geometries, partial quadrangles, semi-partial ge­ ometries, near...

  11. Smaller genitals at school age in boys whose mothers were exposed to non-persistent pesticides in early pregnancy

    DEFF Research Database (Denmark)

    Veje, Christine Wohlfahrt; Andersen, H R; Jensen, Tina Kold

    2012-01-01

    Endocrine disrupting chemicals are believed to play a role in the development of the testicular dysgenesis syndrome. Many pesticides are known to have endocrine disrupting abilities. In a previous study, sons of women who were occupationally exposed to non-persistent pesticides in early pregnancy...... showed signs of impaired reproductive function (reduced genital size and altered serum hormone concentrations) at three months of age. To assess the possible long-term effects of prenatal pesticide exposure, the boys were re-examined at 6-11 years. The 94 boys (59 exposed, 35 unexposed) underwent genital...... penile length (95% CI: -16.8; -1.1) compared with the unexposed. The testicular volume and penile length at school age could be tracked to measures from the same boys made at 3 months, e.g. those that had small testes at school age also had small testes at 3 months. Pituitary and testicular hormone serum...

  12. Catching up with wonderful women: The women-are-wonderful effect is smaller in more gender egalitarian societies.

    Science.gov (United States)

    Krys, Kuba; Capaldi, Colin A; van Tilburg, Wijnand; Lipp, Ottmar V; Bond, Michael Harris; Vauclair, C-Melanie; Manickam, L Sam S; Domínguez-Espinosa, Alejandra; Torres, Claudio; Lun, Vivian Miu-Chi; Teyssier, Julien; Miles, Lynden K; Hansen, Karolina; Park, Joonha; Wagner, Wolfgang; Yu, Angela Arriola; Xing, Cai; Wise, Ryan; Sun, Chien-Ru; Siddiqui, Razi Sultan; Salem, Radwa; Rizwan, Muhammad; Pavlopoulos, Vassilis; Nader, Martin; Maricchiolo, Fridanna; Malbran, María; Javangwe, Gwatirera; Işık, İdil; Igbokwe, David O; Hur, Taekyun; Hassan, Arif; Gonzalez, Ana; Fülöp, Márta; Denoux, Patrick; Cenko, Enila; Chkhaidze, Ana; Shmeleva, Eleonora; Antalíková, Radka; Ahmed, Ramadan A

    2017-03-14

    Inequalities between men and women are common and well-documented. Objective indexes show that men are better positioned than women in societal hierarchies-there is no single country in the world without a gender gap. In contrast, researchers have found that the women-are-wonderful effect-that women are evaluated more positively than men overall-is also common. Cross-cultural studies on gender equality reveal that the more gender egalitarian the society is, the less prevalent explicit gender stereotypes are. Yet, because self-reported gender stereotypes may differ from implicit attitudes towards each gender, we reanalysed data collected across 44 cultures, and (a) confirmed that societal gender egalitarianism reduces the women-are-wonderful effect when it is measured more implicitly (i.e. rating the personality of men and women presented in images) and (b) documented that the social perception of men benefits more from gender egalitarianism than that of women.

  13. Is smaller necessarily better? A systematic review comparing the effects of minilaparoscopic and conventional laparoscopic cholecystectomy on patient outcomes

    DEFF Research Database (Denmark)

    McCloy, R.; Randall, D.; Schug, S.A.;

    2008-01-01

    cosmetic result (largely patient rated). There was a significantly greater likelihood of conversion to conventional LC or to open cholecystectomy in the MLC group than there was of conversion to open cholecystectomy in the conventional LC group [OR 4.71 (95% confidence interval 2.67-8.31), p ... using MEDLINE and EmBASE. Only randomized controlled trials in English, investigating minilaparoscopic versus conventional LC (total size of trocar incision > or = 25 mm) and reporting pain scores were included. Quantitative analyses (meta-analyses) were performed on postoperative pain scores and other...... patient outcomes from more than one study where feasible and appropriate. Qualitative analyses consisted of assessing the number of studies showing a significant difference between the techniques. RESULTS: Thirteen trials met the inclusion criteria. There was a trend towards reduced pain with MLC compared...

  14. Alternative splicing generates a smaller assortment of CaV2.1 transcripts in cerebellar Purkinje cells than in the cerebellum.

    Science.gov (United States)

    Kanumilli, Srinivasan; Tringham, Elizabeth W; Payne, C Elizabeth; Dupere, Jonathan R B; Venkateswarlu, Kanamarlapudi; Usowicz, Maria M

    2006-01-12

    P/Q-type calcium channels control many calcium-driven functions in the brain. The CACNA1A gene encoding the pore-forming CaV2.1 (alpha1A) subunit of P/Q-type channels undergoes alternative splicing at multiple loci. This results in channel variants with different phenotypes. However, the combinatorial patterns of alternative splice events at two or more loci, and hence the diversity of CaV2.1 transcripts, are incompletely defined for specific brain regions and types of brain neurons. Using RT-PCR and splice variant-specific primers, we have identified multiple CaV2.1 transcript variants defined by different pairs of splice events in the cerebellum of adult rat. We have uncovered new splice variations between exons 28 and 34 (some of which predict a premature stop codon) and a new variation in exon 47 (which predicts a novel extended COOH-terminus). Single cell RT-PCR reveals that each individual cerebellar Purkinje neuron also expresses multiple alternative CaV2.1 transcripts, but the assortment is smaller than in the cerebellum. Two of these variants encode different extended COOH-termini which are not the same as those previously reported in Purkinje cells of the mouse. Our patch-clamp recordings show that calcium channel currents in the soma and dendrites of Purkinje cells are largely inhibited by a concentration of omega-agatoxin IVA selective for P-type over Q-type channels, suggesting that the different transcripts may form phenotypic variants of P-type calcium channels in Purkinje cells. These results expand the known diversity of CaV2.1 transcripts in cerebellar Purkinje cells, and propose the selective expression of distinct assortments of CaV2.1 transcripts in different brain neurons and species.

  15. When men appear smaller or larger than they really are: preliminary evidence that women are fooled by size illusions in attractiveness judgment tasks

    Directory of Open Access Journals (Sweden)

    Ludwig Yannick S.

    2014-12-01

    Full Text Available In humans, studies have shown that contrast illusions can affect perceptions of facial attractiveness and dominance. In non-human animals, recent research found that contrast illusions of size positively affected male mate value. In humans, male height is a potentially important indicator of mate value, with women preferring men taller than themselves. We tested in two studies whether height contrast illusions could affect women’s perceptions of male height and mate value, particularly attractiveness, dominance, and muscularity. Using computer-generated images of men of different heights standing in groups of three, 104 female participants rated targets either surrounded by shorter, same height, or taller distractors in a within-subject design. The second experiment (N=80 replicated and extended the first by making the images more realistic and adding natural backgrounds, suggesting that when participants are given a visual anchor, in order to get a better sense of the absolute height of the targets, the effects remain. In both studies, results showed that, compared with same height distractors, male targets were rated as taller when surrounded by shorter distractors, and as shorter when surrounded by taller distractors. Additionally, attractiveness, dominance, and muscularity perceptions were affected in a similar manner, with most of the differences in these appraisals being mediated by the perceived height differences. Therefore, differently sized distractors affected the perceived height and mate value of the targets, which were in effect all of the same constant size. These findings indicate that context dependent effects could potentially influence attractiveness judgments. The same man might thus be perceived as more attractive when surrounded by men of similar or smaller height, as opposed to when surrounded by men who are taller.

  16. STM verification of the reduction of the Young's modulus of CdS nanoparticles at smaller sizes

    Science.gov (United States)

    Hazarika, A.; Peretz, E.; Dikovsky, V.; Santra, P. K.; Shneck, R. Z.; Sarma, D. D.; Manassen, Y.

    2014-12-01

    We demonstrate the first STM evaluation of the Young's modulus (E) of nanoparticles (NPs) of different sizes. The sample deformation induced by tip-sample interaction has been determined using current-distance (I-Z) spectroscopy. As a result of tip-sample interaction, and the induced surface deformations, the I-z curves deviates from pure exponential dependence. Normally, in order to analyze the deformation quantitatively, the tip radius must be known. We show, that this necessity is eliminated by measuring the deformation on a substrate with a known Young's modulus (Au(111)) and estimating the tip radius, and afterwards, using the same tip (with a known radius) to measure the (unknown) Young's modulus of another sample (nanoparticles of CdS). The Young's modulus values found for 3 NP's samples of average diameters of 3.7, 6 and 7.5 nm, were E ~ 73%, 78% and 88% of the bulk value, respectively. These results are in a good agreement with the theoretically predicted reduction of the Young's modulus due to the changes in hydrostatic stresses which resulted from surface tension in nanoparticles with different sizes. Our calculation using third order elastic constants gives a reduction of E which scales linearly with 1/r (r is the NP's radius). This demonstrates the applicability of scanning tunneling spectroscopy for local mechanical characterization of nanoobjects. The method does not include a direct measurement of the tip-sample force but is rather based on the study of the relative elastic response.

  17. 47 CFR 76.7 - General special relief, waiver, enforcement, complaint, show cause, forfeiture, and declaratory...

    Science.gov (United States)

    2010-10-01

    ... FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE... to resolve the problem, except where the only relief sought is a clarification or interpretation of..., such as oral argument or evidentiary hearing directed to particular aspects, as it deems...

  18. Hybrid fibre lighting - directed towards a smaller ecological foot print; Hybrid fiber belysning - rettet mod et mindre oekologisk fodaftryk

    Energy Technology Data Exchange (ETDEWEB)

    Bjarklev, A.; Scolari, L. (DTU Fotonik, Kgs. Lyngby (Denmark)); Bjarklev, A.; Kjaer, T.; Andersen, Jan (RUC-ENSPAC, Roskilde (Denmark)); Trolle, H.; Laursen, K.; Riisberg, V. (Designskolen Kolding, Kolding (Denmark)); Ibsen, P. (IBSEN El-anlaeg ApS, Roskilde (Denmark))

    2010-09-15

    Building on one of the world-leading technologies in fiber optics this project uncovers, whether it is realistic under Danish conditions to exploit opportunities within hybrid fiber illumination - i.e. systems that directly moves the sun indoors via fiber optics. Hybrid lighting is a combination of four technologies: the collection of sunlight (daylight), generation of artificial light, assembly, transportation and distribution of light where needed, and operational control of both natural and artificial light. Some of the significant findings from this project are a design of a hybrid system based on a solar optical system and LED technology, and design and development of fixtures that could combine both daylight and artificial light. The analysis showed that a system based on only LEDs could save 36% energy compared with a system based on the T5 (fluorescent lamps), which today is considered the best available technology. The analysis further indicates an energy saving of 59% when you combine a solar optical system with LED technology in a hybrid system. It is found that there is great potential for further design and applications which can be based for a hybrid lighting combined with the two technologies mentioned above (optical fibers and LEDs). It was also found that hybrid lighting systems are in a very early stage of the innovation life cycle and that one of the most important barriers for successful implementation is the considerably high price. However, this is a typical problem that arises with new technologies and, therefore, further development followed by pilot test projects could bring this technology fast to a more competitive phase, even if one as the basis selects systems based on the T5 technology. There is widespread acceptance of the hybrid system by office users in many areas where it is not possible to have windows, but to make the system work in other sectors, it is necessary to continue research in design that can provide a greater light

  19. Schumpeter's general theory of social evolution

    DEFF Research Database (Denmark)

    Andersen, Esben Sloth

    The recent neo-Schumpeterian and evolutionary economics appears to cover a much smaller range of topics than Joseph Schumpeter confronted. Thus, it has hardly been recognised that Schumpeter wanted to develop a general theory that served the analysis of evolution in any sector of social life as w...

  20. Cosmic Solenoids Minimal Cross-Section and Generalized Flux Quantization

    CERN Document Server

    Davidson, A; Davidson, Aharon; Karasik, David

    1999-01-01

    A self-consistent general relativistic configuration describing a finite cross-section magnetic flux tube is constructed. The cosmic solenoid is modeled by an elastic superconductive surface which separates the Melvin core from the surrounding flat conic structure. We show that a given amount $\\Phi$ of magnetic flux cannot be confined within a cosmic solenoid of circumferential radius smaller than $\\frac{\\sqrt{3G}}{2\\pi c^2}\\Phi$ without creating a conic singularity. Gauss-Codazzi matching conditions are derived by means of a self-consistent action. The source term, representing the surface currents, is sandwiched between internal and external gravitational surface terms. Surface superconductivity is realized by means of a Higgs scalar minimally coupled to projective electromagnetism. Trading the 'magnetic' London phase for a dual 'electric' surface vector potential, the generalized quantization condition reads: $e/{hc} \\Phi + 1/e Q=n$ with $Q$ denoting some dual 'electric' charge, thereby allowing for a non-...

  1. Deaf Individuals Show a Leftward Bias in Numerical Bisection.

    Science.gov (United States)

    Cattaneo, Zaira; Cecchetto, Carlo; Papagno, Costanza

    2016-01-01

    Consistent evidence suggests that deaf individuals conceive of numerical magnitude as a left-to-right-oriented mental number line, as typically observed in hearing individuals. When accessing this spatial representation of numbers, normally hearing individuals typically show an attentional bias to the left (pseudoneglect), resembling the attentional bias they show in physical space. Deaf individuals do not show pseudoneglect in representing external space, as assessed by a visual line bisection task. However, whether deaf individuals show attentional biases in representing numerical space has never been investigated before. Here we instructed groups of deaf and hearing individuals to quickly estimate (without calculating) the midpoint of a series of numerical intervals presented in ascending and descending order. Both hearing and deaf individuals were significantly biased toward lower numbers (i.e., the leftward side of the mental number line) in their estimations. Nonetheless, the underestimation bias was smaller in deaf individuals than in the hearing when bisecting pairs of numbers given in descending order. This result may depend on the use of different strategies by deaf and hearing participants or a less pronounced lateralization of deaf individuals in the control of spatial attention.

  2. Reconstruction of peak water levels, peak discharges and long-term occurrence of extreme- as well as smaller pre-instrumental flood events of river Aare, Limmat, Reuss, Rhine and Saane in Switzerland. Part I

    Science.gov (United States)

    Wetter, Oliver; Tuttenuj, Daniel

    2016-04-01

    systematically analysed the period from 1446-1542 and could prove a large number of pre-instrumental flood events of river Rhine, Birs, Birsig and Wiese in Basel. All in all the weekly led account books contained 54 Rhine flood events, whereas chroniclers and annalists only recorded seven floods during the same period. This is a ratio of almost eight to one. This large difference points to the significantly sharper "observation skills" of the account books towards smaller floods, which may be explained by the fact that bridges can be endangered by relatively small floods because of driftwood, whereas it is known that chroniclers or annalists were predominantly focussing on spectacular (extreme) flood events. We [Oliver Wetter and Daniel Tuttenuj] are now able to present first preliminary results of reconstructed peak water levels and peak discharges of pre instrumental river Aare-, Emme-, Limmat-, Reuss-, Rhine- and Saane floods. These first results clearly show the strengths as well as the limits of the data and method used, depending mainly on the river types. Of the above mentioned rivers only the floods of river Emme could not be reconstructed whereas the long-term development of peak water levels and peak discharges of the other rivers clearly correlate with major local and supra-regional Swiss flood corrections over time. PhD student Daniel Tuttenuj is going to present the results for river Emme and Saane (see Abstract Daniel Tuttenuj), whereas Dr Oliver Wetter is going to present the results for the other rivers and gives a first insight on long-term recurring periods of smaller river Birs-, Birsig-, Rhine- and Wiese flood events based on the analysis of the weekly led account books "Wochenausgabenbücher der Stadt Basel" (see also Abstract of Daniel Tuttenuj).

  3. Reconstruction of peak water levels, peak discharges and long-term occurrence of extreme- as well as smaller pre-instrumental flood events of river Aare, Limmat, Reuss, Rhine and Saane in Switzerland. Part II.

    Science.gov (United States)

    Tuttenuj, Daniel; Wetter, Oliver

    2016-04-01

    contained 54 Rhine flood events, whereas chroniclers and annalists only recorded seven floods during the same period. This is a ratio of almost eight to one. This large difference points to the significantly sharper "observation skills" of the account books towards smaller floods, which may be explained by the fact that bridges can be endangered by relatively small floods because of driftwood, whereas it is known that chroniclers or annalists were predominantly focussing on spectacular (extreme) flood events. We [Oliver Wetter and Daniel Tuttenuj] are now able to present first preliminary results of reconstructed peak water levels and peak discharges of pre instrumental river Aare-, Emme-, Limmat-, Reuss-, Rhine- and Saane floods. These first results clearly show the strengths as well as the limits of the data and method used, depending mainly on the river types. Of the above mentioned rivers only the floods of river Emme could not be reconstructed whereas the long-term development of peak water levels and peak discharges of the other rivers clearly correlate with major local and supra-regional Swiss flood corrections over time. PhD student Daniel Tuttenuj is going to present the results of river Emme and Saane, whereas Dr Oliver Wetter is going to present the results for the other rivers and gives a first insight on long-term recurring periods of smaller river Birs, Birsig, Rhine and Wiese flood events based on the analysis of the weekly led account books "Wochenausgabenbücher der Stadt Basel" (see Abstract Oliver Wetter).

  4. Generalized Galilean Genesis

    CERN Document Server

    Nishi, Sakine

    2015-01-01

    The galilean genesis scenario is an alternative to inflation in which the universe starts expanding from Minkowski in the asymptotic past by violating the null energy condition stably. Several concrete models of galilean genesis have been constructed so far within the context of galileon-type scalar-field theories. We give a generic, unified description of the galilean genesis scenario in terms of the Horndeski theory, i.e., the most general scalar-tensor theory with second-order field equations. In doing so we generalize the previous models to have a new parameter (denoted by {\\alpha}) which results in controlling the evolution of the Hubble rate. The background dynamics is investigated to show that the generalized galilean genesis solution is an attractor, similarly to the original model. We also study the nature of primordial perturbations in the generalized galilean genesis scenario. In all the models described by our generalized genesis Lagrangian, amplification of tensor perturbations does not occur as ...

  5. General Relativity

    CERN Document Server

    Khriplovich, I. B

    2005-01-01

    This book offers an alternative to other textbooks on the subject, providing a more specific discussion of numerous general relativistic effects for readers who have knowledge of classical mechanics and electrodynamics, including special relativity. Coverage includes gravitational lensing, signal retardation in the gravitational field of the Sun, the Reissner-Nordström solution, selected spin effects, the resonance transformation of an electromagnetic wave into a gravitational one, and the entropy and temperature of black holes. The book includes numerous problems at various levels of difficulty, making it ideal also for independent study by a broad readership of advanced students and researchers. I.B. Khriplovich is Chief Researcher, Budker Institute of Nuclear Physics, Novosibirsk, and Chair of Theoretical Physics at Novosibirsk University. Dr. Khriplovich is a Corresponding Member of the Russian Academy of Sciences. He has been awarded the Dirac Medal ``For the advancement of theoretical physics'' by Univ...

  6. [General anesthesia].

    Science.gov (United States)

    Feiss, P

    2001-04-30

    General anaesthesia is a reversible loss of consciousness induced and maintained with a hypnotic drug given either by venous injection and infusion, or by inhalation. A potent opioid is usually associated to inhibit the transmission of pain and thus to lessen sympathetic and endocrine reactions to nociceptive stimuli. Myorelaxation is used to facilitate tracheal intubation and surgery. Whatever the anaesthetic protocol use, the patient and anaesthesia machine require close monitoring. In addition to vital signs, the depth of anaesthesia may be monitored using automated electroencephalographic analysis and myorelaxation should always be monitored using a nerve stimulator, but pain or analgesia evaluation is only based on clinical signs of sympathetic stimulation. Because anaesthesia-related death and morbidity have decreased considerably, future improvements in outcome should concern perioperative comfort, i.e. prevention of cognitive disturbances, nausea, vomiting and pain.

  7. General artificial neuron

    Science.gov (United States)

    Degeratu, Vasile; Schiopu, Paul; Degeratu, Stefania

    2007-05-01

    In this paper the authors present a model of artificial neuron named the general artificial neuron. Depending on application this neuron can change self number of inputs, the type of inputs (from excitatory in inhibitory or vice versa), the synaptic weights, the threshold, the type of intensifying functions. It is achieved into optoelectronic technology. Also, into optoelectronic technology a model of general McCulloch-Pitts neuron is showed. The advantages of these neurons are very high because we have to solve different applications with the same neural network, achieved from these neurons, named general neural network.

  8. Allowable Generalized Quantum Gates

    Institute of Scientific and Technical Information of China (English)

    LONG Gui-Lu; LIU Yang; WANG Chuan

    2009-01-01

    In this paper, we give the most general duality gates, or generalized quantum gates in duality quantum computers. Here we show by explicit construction that a n-bit duality quantum computer with d slits can be simulated perfectly with an ordinary quantum computer with n qubits and one auxiliary qudit. Using this model, we give the most general form of duality gates which is of the form Σ(d-1)(i=0)piUi, and the Pi's are complex numbers with module less or equal to I and constrained by |Σipi|≤1.

  9. Generalized Klein-Nishina formula

    CERN Document Server

    Krajewska, K; Kamiński, J Z

    2015-01-01

    The generalized Klein-Nishina formula for Compton scattering of charged particles by a finite train of pulses is derived in the framework of quantum electrodynamics. The formula also applies to classical Thomson scattering provided that frequencies of generated radiation are smaller that the cut-off frequency. The validity of the formula for incident pulses of different durations is illustrated by numerical examples. The positions of the well-resolved Compton peaks, with the clear labeling by integer orders, opens up the possibility of the precise diagnostics of properties of relativistically intense, short laser pulses. This includes their peak intensity, the carrier-envelope phase, and their polarization properties.

  10. Identified motor terminals in Drosophila larvae show distinct differences in morphology and physiology

    Science.gov (United States)

    Lnenicka, G. A.; Keshishian, H.

    2000-01-01

    In Drosophila, the type I motor terminals innervating the larval ventral longitudinal muscle fibers 6 and 7 have been the most popular preparation for combining synaptic studies with genetics. We have further characterized the normal morphological and physiological properties of these motor terminals and the influence of muscle size on terminal morphology. Using dye-injection and physiological techniques, we show that the two axons supplying these terminals have different innervation patterns: axon 1 innervates only muscle fibers 6 and 7, whereas axon 2 innervates all of the ventral longitudinal muscle fibers. This difference in innervation pattern allows the two axons to be reliably identified. The terminals formed by axons 1 and 2 on muscle fibers 6 and 7 have the same number of branches; however, axon 2 terminals are approximately 30% longer than axon 1 terminals, resulting in a corresponding greater number of boutons for axon 2. The axon 1 boutons are approximately 30% wider than the axon 2 boutons. The excitatory postsynaptic potential (EPSP) produced by axon 1 is generally smaller than that produced by axon 2, although the size distributions show considerable overlap. Consistent with vertebrate studies, there is a correlation between muscle fiber size and terminal size. For a single axon, terminal area and length, the number of terminal branches, and the number of boutons are all correlated with muscle fiber size, but bouton size is not. During prolonged repetitive stimulation, axon 2 motor terminals show synaptic depression, whereas axon 1 EPSPs facilitate. The response to repetitive stimulation appears to be similar at all motor terminals of an axon. Copyright 2000 John Wiley & Sons, Inc.

  11. Smaller plates, less food waste

    DEFF Research Database (Denmark)

    Hansen, Pelle Guldborg; Schmidt, Karsten; Skov, Laurits Rhoden

    and producers. Northern European consumers are among the most environmentally concerned consumers, however, their concerns do not always translate in more sustainable food-related behaviours. Furthermore, food choices are not always rational and could be non-reflective. Hence, the objective of this pilot study......With roughly one-third of food produced for human consumption lost or wasted globally (about 1.3 billion tons per year), the impact on the environment cannot be anymore neglected. Actions at all points in the production chain are now urgent, including reductions in food waste at home, by retailers...... was to investigate whether the size of the dishware would non-reflectively influence the amount of foods taken from an “ad-libitum” buffet and the resulting amount of waste. Sample consisted of Danish business leaders that took part in a congress in Copenhagen, Denmark. Two buffet tables were set up on two separate...

  12. Smaller magnets for smarter minds?

    Science.gov (United States)

    Muggleton, Neil; Walsh, Vincent

    2012-09-01

    Human brain stimulation for therapeutic purposes has many short- and long-term limitations. The possibility of implanting magnetic, rather than electrical, stimulation devices would present a possible solution to some of the problems. The development of a new microscopic magnetic stimulation device provides a glimpse of the realisation.

  13. Fabrics China Creation Show Hold in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ On August 5-6th.the 3rd Fabrics China Creation Show(one series events of Reach & Touch),organized by China National Textile & Apparel Council and National Textile Development Center,was held in Shanghai,aiming to providing textile producers and designers a platform to show their inspirations and creative ideas in fabric design.

  14. Serving Up Activities for TV Cooking Shows.

    Science.gov (United States)

    Katchen, Johanna E.

    This paper documents a presentation given on the use of English-language television cooking shows in English-as-a-Second-Language (ESL) and English-as-a-Foreign-Language (EFL) classrooms in Taiwan. Such shows can be ideal for classroom use, since they have a predictable structure consisting of short segments, are of interest to most students,…

  15. Voyeurismo Televisivo, Reality Shows e Brasilidade Televisiva

    Directory of Open Access Journals (Sweden)

    Suzana Kilpp

    2008-12-01

    Full Text Available In the last years we watched a boom of reality shows in the media and also in the academic production specialized in this subject. It remains, however, a epistemological gap related to the aesthetic and techniques (which are related to the televisions grammars that TV uses in these programs to enunciate ethics directions to its own voyeurism, that goes far beyond reality shows, having repercussions on social imaginary of transparency and surveillance, and the redesign of public and private spaces. In this gap, the article points out the debate of Brazilian reality shows in the perspective of the televisions grammars.

  16. Fecal Transplant Shows Early Promise Against Autism

    Science.gov (United States)

    ... 163263.html Fecal Transplant Shows Early Promise Against Autism Small study found giving healthy gut bacteria to ... study suggests a novel treatment for kids with autism: Give these young patients a fresh supply of ...

  17. Poverty Harder on Women's Hearts, Research Shows

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_163168.html Poverty Harder on Women's Hearts, Research Shows Poor females ... reduce the burden of cardiovascular disease around the world," Peters said. The study findings were published online ...

  18. Diabetes Drug Shows Promise Against Parkinson's

    Science.gov (United States)

    ... fullstory_167612.html Diabetes Drug Shows Promise Against Parkinson's Byetta improved symptoms of motor disease in small, ... may do double duty as a treatment for Parkinson's disease, a new study suggests. "This is a ...

  19. UV Photography Shows Hidden Sun Damage

    Science.gov (United States)

    ... mcat1=de12", ]; for (var c = 0; c UV photography shows hidden sun damage A UV photograph gives ... developing skin cancer and prematurely aged skin. Normal photography UV photography 18 months of age: This boy's ...

  20. Study Shows How Zika Attacks Infant Brain

    Science.gov (United States)

    ... gov/news/fullstory_162514.html Study Shows How Zika Attacks Infant Brain Virus can copy itself thousands ... New research paints a chilling portrait of how Zika ravages the infant brain. Scientists from the U.S. ...

  1. Fabrics China Creation Show Held in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    On August 5-6th,the 3rd Fabrics China Creation Show (one series events of Reach & Touch),organized by China National Textile & Apparel Council and National Textile Development Center,was held in Shanghai,

  2. Voyeurismo Televisivo, Reality Shows e Brasilidade Televisiva

    OpenAIRE

    Suzana Kilpp

    2008-01-01

    In the last years we watched a boom of reality shows in the media and also in the academic production specialized in this subject. It remains, however, a epistemological gap related to the aesthetic and techniques (which are related to the televisions grammars) that TV uses in these programs to enunciate ethics directions to its own voyeurism, that goes far beyond reality shows, having repercussions on social imaginary of transparency and surveillance, and the redesign of public and private s...

  3. Generalized Higher Gauge Theory

    CERN Document Server

    Ritter, Patricia; Schmidt, Lennart

    2015-01-01

    We study a generalization of higher gauge theory which makes use of generalized geometry and seems to be closely related to double field theory. The local kinematical data of this theory is captured by morphisms of graded manifolds between the canonical exact Courant Lie 2-algebroid $TM\\oplus T^*M$ over some manifold $M$ and a semistrict gauge Lie 2-algebra. We discuss generalized curvatures and their infinitesimal gauge transformations. Finite gauge transformation as well as global kinematical data are then obtained from principal 2-bundles over 2-spaces. As dynamical principle, we consider first the canonical Chern-Simons action for such a gauge theory. We then show that a previously proposed 3-Lie algebra model for the six-dimensional (2,0) theory is very naturally interpreted as a generalized higher gauge theory.

  4. Generalizing the Lorentz transformations

    CERN Document Server

    Chappell, James M; Iannella, Nicolangelo; Hartnett, John G; Iqbal, Azhar; Abbott, Derek

    2016-01-01

    In this paper we develop a framework allowing a natural extension of the Lorentz transformations. To begin, we show that by expanding conventional four-dimensional spacetime to eight-dimensions that a natural generalization is indeed obtained. We then find with these generalized coordinate transformations acting on Maxwell's equations that the electromagnetic field transformations are nevertheless unchanged. We find further, that if we assume the absence of magnetic monopoles, in accordance with Maxwell's theory, our generalized transformations are then restricted to be the conventional ones. While the conventional Lorentz transformations are indeed recovered from our framework, we nevertheless provide a new perspective into why the Lorentz transformations are constrained to be the conventional ones. Also, this generalized framework may assist in explaining several unresolved questions in electromagnetism as well as to be able to describe quasi magnetic monopoles found in spin-ice systems.

  5. A Generalization of Generalized Fibonacci and Generalized Pell Numbers

    Science.gov (United States)

    Abd-Elhameed, W. M.; Zeyada, N. A.

    2017-01-01

    This paper is concerned with developing a new class of generalized numbers. The main advantage of this class is that it generalizes the two classes of generalized Fibonacci numbers and generalized Pell numbers. Some new identities involving these generalized numbers are obtained. In addition, the two well-known identities of Sury and Marques which…

  6. GENERAL GEOLOGY

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>20110727 Dai Deqiu (Institute of Geology, Hunan University of Science and Technology, Xiangtan 411201, China); Wang Daode The Evolvement Models and Progress of Research on Formation of Ca-,Al-Rich inclusions in Chondrites (Geological Review, ISSN0371-5736, CN11-1952/P, 56(3), 2010, p.374-383, 2 illus., 1 table, 72 refs.)Key words: chondrites Ca-, Al-rich inclusions (CAIs) are the earliest assemblages formed in the solar nebula. The formation models of CAIs include gas-soild condensation, crystallization from melting or partial melting and high-temperature evaporating residues. The latest study shows similar distribution patterns of the petrographic types and sizes of CAIs in various chondrites. The petrographic characters argue that CAIs in various chemical groups of chondrites formed under similar processes and conditions probably in a same region in the solar nebula.

  7. Comparison of retrograde intrarenal surgery and mini-percutaneous nephrolithotomy in management of lower-pole renal stones with a diameter of smaller than 15 mm.

    Science.gov (United States)

    Kirac, Mustafa; Bozkurt, Ömer Faruk; Tunc, Lutfi; Guneri, Cagri; Unsal, Ali; Biri, Hasan

    2013-06-01

    The aim of this study was to compare the outcomes of retrograde intrarenal surgery (RIRS) and miniaturized percutaneous nephrolithotomy (mini-PNL) in management of lower-pole renal stones with a diameter smaller than 15 mm. Between December 2009 and July 2012, the patients with the diagnosis of lower-pole stones were evaluated by ultrasonography, intravenous pyelography and computed tomography. The records of 73 evaluable patients who underwent mini-PNL (n = 37) or RIRS (n = 36) for lower-pole (LP) stones with diameter smaller than 15 mm were reviewed retrospectively. Of the 73 patients, 37 underwent mini-PNL and 36 underwent RIRS. The stone-free rates were 89.1 and 88.8 % for mini-PNL and RIRS groups, respectively. The mean operation time was 53.7 ± 14.5 in the mini-PNL group but 66.4 ± 15.8 in the RIRS group (P = 0.01). The mean fluoroscopy times and hospitalization times were significantly higher in the mini-PNL group. There was no major complication in any patient. RIRS and mini-PNL are safe and effective methods for treatment of LP calculi with a diameter smaller than 15 mm. RIRS is a non-invasive and feasible treatment option, and has also short hospitalization time, low morbidity and complication rate. It may be an alternative of mini-PNL in the treatment LP calculi with smaller than 15 mm.

  8. Online Italian fandoms of American TV shows

    Directory of Open Access Journals (Sweden)

    Eleonora Benecchi

    2015-06-01

    Full Text Available The Internet has changed media fandom in two main ways: it helps fans connect with each other despite physical distance, leading to the formation of international fan communities; and it helps fans connect with the creators of the TV show, deepening the relationship between TV producers and international fandoms. To assess whether Italian fan communities active online are indeed part of transnational online communities and whether the Internet has actually altered their relationship with the creators of the original text they are devoted to, qualitative analysis and narrative interviews of 26 Italian fans of American TV shows were conducted to explore the fan-producer relationship. Results indicated that the online Italian fans surveyed preferred to stay local, rather than using geography-leveling online tools. Further, the sampled Italian fans' relationships with the show runners were mediated or even absent.

  9. 2008 LHC Open Days Physics: the show

    CERN Document Server

    2008-01-01

    A host of events and activities await visitors to the LHC Open Days on 5 and 6 April. A highlight will be the physics shows funded by the European Physical Society (EPS), which are set to surprise and challenge children and adults alike! School children use their experience of riding a bicycle to understand how planets move around the sun (Copyright : Circus Naturally) Participating in the Circus Naturally show could leave a strange taste in your mouth! (Copyright : Circus Naturally) The Rino Foundation’s experiments with liquid nitrogen can be pretty exciting! (Copyright: The Rino Foundation)What does a bicycle have in common with the solar system? Have you ever tried to weigh air or visualise sound? Ever heard of a vacuum bazooka? If you want to discover the answers to these questions and more then come to the Physics Shows taking place at the CERN O...

  10. Liquid Crystal Research Shows Deformation By Drying

    Science.gov (United States)

    2003-01-01

    These images, from David Weitz's liquid crystal research, show ordered uniform sized droplets (upper left) before they are dried from their solution. After the droplets are dried (upper right), they are viewed with crossed polarizers that show the deformation caused by drying, a process that orients the bipolar structure of the liquid crystal within the droplets. When an electric field is applied to the dried droplets (lower left), and then increased (lower right), the liquid crystal within the droplets switches its alignment, thereby reducing the amount of light that can be scattered by the droplets when a beam is shone through them.

  11. The use of generalized functions and distributions in general relativity

    Energy Technology Data Exchange (ETDEWEB)

    Steinbauer, R [Department of Mathematics, University of Vienna, Nordbergstrasse 15, A-1090 Wien (Austria); Vickers, J A [School of Mathematics, University of Southampton, Southampton SO17 1BJ (United Kingdom)

    2006-05-21

    We review the extent to which one can use classical distribution theory in describing solutions of Einstein's equations. We show that there are a number of physically interesting cases which cannot be treated using distribution theory but require a more general concept. We describe a mathematical theory of nonlinear generalized functions based on Colombeau algebras and show how this may be applied in general relativity. We end by discussing the concept of singularity in general relativity and show that certain solutions with weak singularities may be regarded as distributional solutions of Einstein's equations. (topical review)

  12. A Talk Show from the Past.

    Science.gov (United States)

    Gallagher, Arlene F.

    1991-01-01

    Describes a two-day activity in which elementary students examine voting rights, the right to assemble, and women's suffrage. Explains the game, "Assemble, Reassemble," and a student-produced talk show with five students playing the roles of leaders of the women's suffrage movement. Profiles Elizabeth Cady Stanton, Lucretia Mott, Susan…

  13. The Last Great American Picture Show

    NARCIS (Netherlands)

    Elsaesser, Thomas; King, Noel; Horwath, Alexander

    2004-01-01

    The Last Great American Picture Show brings together essays by scholars and writers who chart the changing evaluations of the American cinema of the 1970s, sometimes referred to as the decade of the lost generation, but now more and more recognized as the first New Hollywood, without which the cinem

  14. Gene Therapy Shows Promise for Aggressive Lymphoma

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_163824.html Gene Therapy Shows Promise for Aggressive Lymphoma Over one-third ... TUESDAY, Feb. 28, 2017 (HealthDay News) -- An experimental gene therapy for aggressive non-Hodgkin lymphoma beat back more ...

  15. Development, management and economy of show caves.

    Directory of Open Access Journals (Sweden)

    Cigna Arrigo A.

    2000-01-01

    Full Text Available The problems concerning the development of show caves are here considered by taking into account different aspects of the problem. A procedure to carry out an Environmental Impact Assessment (EIA has been established in the last decade and it is now currently applied. Such an assessment starts with a pre-operational phase to obtain sufficient information on the undisturbed status of a cave to be developed into a show cave. Successively a programme for its development is established with the scope to optimise the intervention on the cave at the condition that its basic environmental parameters are not irreversibly modified. The last phase of the assessment is focussed to assure a feedback through a monitoring network in order to detect any unforeseen difference or anomaly between the project and the effective situation achieved after the cave development. Some data on some of the most important show caves in the world are reported and a tentative evaluation of the economy in connection with the show caves business is eventually made.

  16. Show Them You Really Want the Job

    Science.gov (United States)

    Perlmutter, David D.

    2012-01-01

    Showing that one really "wants" the job entails more than just really wanting the job. An interview is part Broadway casting call, part intellectual dating game, part personality test, and part, well, job interview. When there are 300 applicants for a position, many of them will "fit" the required (and even the preferred) skills listed in the job…

  17. TV-Show Retrieval and Classification

    NARCIS (Netherlands)

    Musto, C.; Narducci, F.; Lops, P.; Semeraro G.; Gemmis, M. de; Barbieri, M.; Korst, J.H.M.; Pronk, S.P.P.; Clout, R.A.W.

    2012-01-01

    Recommender systems are becoming popular tools to aid users in finding interesting and relevant TV-shows and other digital video assets,based on implicitly learned user preferences. In this context, a common assumption is that user preferences can be specified by program types (movie, sports, ...) a

  18. The British Show in Australia, 1985

    Directory of Open Access Journals (Sweden)

    Anthony Bond

    2016-07-01

    Full Text Available In 1984–85, The British Show, an exhibition largely made up of New British Sculpture, was curated for Australia and New Zealand. This essay discusses the context and effects of the exhibition on art in Australia. It also seeks to define the sources of originality and innovation of the artists included.

  19. Laser entertainment and light shows in education

    Science.gov (United States)

    Sabaratnam, Andrew T.; Symons, Charles

    2002-05-01

    Laser shows and beam effects have been a source of entertainment since its first public performance May 9, 1969, at Mills College in Oakland, California. Since 1997, the Photonics Center, NgeeAnn Polytechnic, Singapore, has been using laser shows as a teaching tool. Students are able to exhibit their creative skills and learn at the same time how lasers are used in the entertainment industry. Students will acquire a number of skills including handling three- phase power supply, operation of cooling system, and laser alignment. Students also acquire an appreciation of the arts, learning about shapes and contours as they develop graphics for the shows. After holography, laser show animation provides a combination of the arts and technology. This paper aims to briefly describe how a krypton-argon laser, galvanometer scanners, a polychromatic acousto-optic modulator and related electronics are put together to develop a laser projector. The paper also describes how students are trained to make their own laser animation and beam effects with music, and at the same time have an appreciation of the operation of a Class IV laser and the handling of optical components.

  20. Generalized Quantization Condition

    Institute of Scientific and Technical Information of China (English)

    LIANG Zheng; CAO Zhuang-Qi; DENG Xiao-Xu; SHEN Qi-Shun

    2005-01-01

    @@ On the basis of analytical transfer matrix theory, we fine a generalized quantization condition. By introducing a new type of modified momentum, our quantization condition has the same form as the Bohr-Sommerfeld formula.Numerical and analytical comparisons show that the present method is exact.

  1. One pass learning for generalized classifier neural network.

    Science.gov (United States)

    Ozyildirim, Buse Melis; Avci, Mutlu

    2016-01-01

    Generalized classifier neural network introduced as a kind of radial basis function neural network, uses gradient descent based optimized smoothing parameter value to provide efficient classification. However, optimization consumes quite a long time and may cause a drawback. In this work, one pass learning for generalized classifier neural network is proposed to overcome this disadvantage. Proposed method utilizes standard deviation of each class to calculate corresponding smoothing parameter. Since different datasets may have different standard deviations and data distributions, proposed method tries to handle these differences by defining two functions for smoothing parameter calculation. Thresholding is applied to determine which function will be used. One of these functions is defined for datasets having different range of values. It provides balanced smoothing parameters for these datasets through logarithmic function and changing the operation range to lower boundary. On the other hand, the other function calculates smoothing parameter value for classes having standard deviation smaller than the threshold value. Proposed method is tested on 14 datasets and performance of one pass learning generalized classifier neural network is compared with that of probabilistic neural network, radial basis function neural network, extreme learning machines, and standard and logarithmic learning generalized classifier neural network in MATLAB environment. One pass learning generalized classifier neural network provides more than a thousand times faster classification than standard and logarithmic generalized classifier neural network. Due to its classification accuracy and speed, one pass generalized classifier neural network can be considered as an efficient alternative to probabilistic neural network. Test results show that proposed method overcomes computational drawback of generalized classifier neural network and may increase the classification performance. Copyright

  2. La mujer, en los talk shows

    Directory of Open Access Journals (Sweden)

    Antrop. José Gamboa Cetina

    2001-01-01

    Full Text Available Dentro de los medios de comunicación, uno de los que más ha impactado a la población latinoamericana ha sido la televisión, y en la barra programática de las televisoras ha surgido un tipo de programas denominados talk shows. En los últimos meses, la sociedad mexicana ha vivido el "boom" de los talk shows, que en poco tiempo han saturado la barra de la programación vespertina de las dos principales empresas televisivas de la república mexicana. Este fenómeno puede estudiarse desde diversas perspectivas. Sin embargo, por motivos de espacio, en esta ocasión analizaremos su impacto en las mujeres, desde diferentes dimensiones.

  3. 2009 Hands Across Pacific Show Held

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    <正>The 2009 Hands Across the Pacific Show co-sponsored by the Canadian International Cultural Exchanges (CICEX) and Hunan Provincial People’s Association for Friendship with Foreign Countries(HPPAFFC) was held respectively in the Tower Hall of Tokyo,Japan from July 2 to 7 and in the Hunan Provincial Museum from August 1 to 5.Jing Dunquan,Vice President of the

  4. The People's Show: A Critical Analysis

    OpenAIRE

    Robin Francis

    1996-01-01

    The 1990s heralded a new form of museum exhibition: "The People's Show." A light-hearted celebration of popular culture, the concept has had phenomenal success throughout the United Kingdom. Beneath the humour, however, are more complex and radical agendas relating to cultural rights. The paper explores the issues associated with the rise and possible wane of this museum-based popular cultural phenomenon.

  5. Reality, ficción o show

    Directory of Open Access Journals (Sweden)

    Sandra Ruíz Moreno

    2002-01-01

    Full Text Available Para tener un punto de vista claro y objetivo frente a la polémica establecida en torno al programa “Protagonistas de novela” y la tendiente proliferación de los reality show en las parrillas de programación de la televisión colombiana, se realizó un análisis de texto y contenido de dicho programa, intentando definirlo desde sus posibilidades de realidad, ficción y show. Las unidades de análisis y el estudio de su tratamiento arrojaron un alto contenido que gira en torno a las emociones del ser humano relacionadas con la convivencia, tratadas a manera de show y con algunos aportes textuales de ficción, pero sin su elemento mediador básico, el actor, quitándole toda la posibilidad de tener un tratamiento con la profundidad, distancia y ética que requieren los temas de esta índole. El resultado es un formato que sólo busca altos índices de sintonía y que pertenece más a la denominada televisión “trash”, que a una búsqueda de realidad del hombre y mucho menos de sociedad.

  6. Generalized galilean genesis

    Energy Technology Data Exchange (ETDEWEB)

    Nishi, Sakine; Kobayashi, Tsutomu [Department of Physics, Rikkyo University, Toshima, Tokyo 175-8501 (Japan)

    2015-03-31

    The galilean genesis scenario is an alternative to inflation in which the universe starts expanding from Minkowski in the asymptotic past by violating the null energy condition stably. Several concrete models of galilean genesis have been constructed so far within the context of galileon-type scalar-field theories. We give a generic, unified description of the galilean genesis scenario in terms of the Horndeski theory, i.e., the most general scalar-tensor theory with second-order field equations. In doing so we generalize the previous models to have a new parameter (denoted by α) which results in controlling the evolution of the Hubble rate. The background dynamics is investigated to show that the generalized galilean genesis solution is an attractor, similarly to the original model. We also study the nature of primordial perturbations in the generalized galilean genesis scenario. In all the models described by our generalized genesis Lagrangian, amplification of tensor perturbations does not occur as opposed to what happens in quasi-de Sitter inflation. We show that the spectral index of curvature perturbations is determined solely from the parameter α and does not depend on the other details of the model. In contrast to the original model, a nearly scale-invariant spectrum of curvature perturbations is obtained for a specific choice of α.

  7. Whistler-Mode Waves Growth by a Generalized Relativistic Kappa-Type Distribution

    Institute of Scientific and Technical Information of China (English)

    ZHOU Qing-Hua; JIANG Bin; SHI Xiang-Hua; LI Jun-Qiu

    2009-01-01

    The instability of field-aligned Whistler-mode waves in space plasmas is studied by using a recently developed generalized relativistic kappa-type (KT) distribution. Numerical calculations are performed for a direct compar-ison between the new KT distribution and the current kappa distribution. We show that the wave growth for the KT distribution tends to occur in the lower wave frequency (e.g., ω 0.1Ωe) due to a larger fractional num-ber of the resonant electrons ηrel (which controls the wave growth), while primarily locating in the higher wave frequency for the kappa distribution. Moreover, the relativistic anisotropy Arel by the KT distribution is found to be smaller than that by the kappa distribution, leading to a smaller peak of wave growth. The results present a further understanding of plasma wave instability particularly in those plasmas where relativistic electrons are present.

  8. Showing and Saying. An Aesthetic Difference

    Directory of Open Access Journals (Sweden)

    Vicente Sanfélix Vidarte

    2013-05-01

    Full Text Available Wittgenstein’s distinction between saying and showing and the associated thesis, what can be shown cannot be said, were crucial to his first philosophy, persisted throughout the evolution of his whole thought and played a key role in his views on aesthetics. The objective of art is access to the mystical, forcing us to become aware of the uniqueness of our own experience and life. When art is good is a perfect expression and the work of art becomes like a tautology. An important consequence of this understanding of art is the irreducibility of the aesthetic to the scientific perspective.

  9. Latest European coelacanth shows Gondwanan affinities.

    Science.gov (United States)

    Cavin, Lionel; Forey, Peter L; Buffetaut, Eric; Tong, Haiyan

    2005-06-22

    The last European fossil occurrence of a coelacanth is from the Mid-Cretaceous of the English Chalk (Turonian, 90 million years ago). Here, we report the discovery of a coelacanth from Late Cretaceous non-marine rocks in southern France. It consists of a left angular bone showing structures that imply close phylogenetic affinities with some extinct Mawsoniidae. The closest relatives are otherwise known from Cretaceous continental deposits of southern continents and suggest that the dispersal of freshwater organisms from Africa to Europe occurred in the Late Cretaceous.

  10. Quantifying causal emergence shows that macro can beat micro.

    Science.gov (United States)

    Hoel, Erik P; Albantakis, Larissa; Tononi, Giulio

    2013-12-01

    Causal interactions within complex systems can be analyzed at multiple spatial and temporal scales. For example, the brain can be analyzed at the level of neurons, neuronal groups, and areas, over tens, hundreds, or thousands of milliseconds. It is widely assumed that, once a micro level is fixed, macro levels are fixed too, a relation called supervenience. It is also assumed that, although macro descriptions may be convenient, only the micro level is causally complete, because it includes every detail, thus leaving no room for causation at the macro level. However, this assumption can only be evaluated under a proper measure of causation. Here, we use a measure [effective information (EI)] that depends on both the effectiveness of a system's mechanisms and the size of its state space: EI is higher the more the mechanisms constrain the system's possible past and future states. By measuring EI at micro and macro levels in simple systems whose micro mechanisms are fixed, we show that for certain causal architectures EI can peak at a macro level in space and/or time. This happens when coarse-grained macro mechanisms are more effective (more deterministic and/or less degenerate) than the underlying micro mechanisms, to an extent that overcomes the smaller state space. Thus, although the macro level supervenes upon the micro, it can supersede it causally, leading to genuine causal emergence--the gain in EI when moving from a micro to a macro level of analysis.

  11. Congenital myotonic dystrophy can show congenital fiber type disproportion pathology.

    Science.gov (United States)

    Tominaga, Kayo; Hayashi, Yukiko K; Goto, Kanako; Minami, Narihiro; Noguchi, Satoru; Nonaka, Ikuya; Miki, Tetsuro; Nishino, Ichizo

    2010-04-01

    Congenital myotonic dystrophy (CDM) is associated with markedly expanded CTG repeats in DMPK. The presence of numerous immature fibers with peripheral halo is a characteristic feature of CDM muscles together with hypotrophy of type 1 fibers. Smaller type 1 fibers with no structural abnormality are a definitive criterion of congenital fiber type disproportion (CFTD). Nonetheless, we recently came across a patient who was genetically confirmed as CDM, but had been earlier diagnosed as CFTD when he was an infant. In this study, we performed clinical, pathological, and genetic analyses in infantile patients pathologically diagnosed as CFTD to evaluate CDM patients indistinguishable from CFTD. We examined CTG repeat expansion in DMPK in 28 infantile patients pathologically diagnosed as CFTD. Mutation screening of ACTA1 and TPM3 was performed, and we compared clinical and pathological findings of 20 CDM patients with those of the other cohorts. We identified four (14%) patients with CTG expansion in DMPK. ACTA1 mutation was identified in four (14%), and TPM3 mutation was found in two (7%) patients. Fiber size disproportion was more prominent in patients with ACTA1 or TPM3 mutations as compared to CFTD patients with CTG expansion. A further three patients among 20 CDM patients showed pathological findings similar to CFTD. From our results, CDM should be excluded in CFTD patients.

  12. Devices for separation of particle emissions from biofuel plants smaller than 10 MW - Today's technology and potential for development; Stoftreningsteknik foer biobraensleanlaeggningar mindre aen 10 MW - tekniklaege och utvecklingspotential

    Energy Technology Data Exchange (ETDEWEB)

    Roennbaeck, Marie; Gustavsson, Lennart; Martinsson, Lars; Tullin, Claes; Johansson, Linda

    2002-09-01

    towards separation of smaller particles are beds filled with gravel or granulate for ionised flue gas, found installed in Sweden and in a research plant in Denmark. In Germany a combined cyclone/fabric filter/catalytic converter is developed, with the requested ability to separate submicron particles. In Norway a panel bed filter has been tested, working on the same principle as a fabric filter showing good abilities to separate submicron particles. It is uncertain if any of these mentioned new technologies will show to be competitive besides the already established ones. The knowledge of how particles are formed, how load and operation of the specific plant influence on the formation, how the particles are distributed in size and mass and their chemical composition, is limited. To meet the demand for good air quality at the same time as combustion of biofuel in small scale plants is increased, there is a need for more research and more measurements to cast light on both mechanisms for formation and separation. Possibilities have to be given to realise new ideas and to test them in practise.

  13. Generalized Erdos Numbers

    CERN Document Server

    Morrison, Greg

    2010-01-01

    We propose a simple real-valued generalization of the well known integer-valued Erdos number as a topological, non-metric measure of the `closeness' felt between two nodes in an undirected, weighted graph. These real-valued Erdos numbers are asymmetric and are able to distinguish between network topologies that standard distance metrics view as identical. We use this measure to study some simple analytically tractable networks, and show the utility of our measure to devise a ratings scheme based on the generalized Erdos number that we deploy on the data from the NetFlix prize, and find a significant improvement in our ratings prediction over a baseline.

  14. Lectures in general algebra

    CERN Document Server

    Kurosh, A G; Stark, M; Ulam, S

    1965-01-01

    Lectures in General Algebra is a translation from the Russian and is based on lectures on specialized courses in general algebra at Moscow University. The book starts with the basics of algebra. The text briefly describes the theory of sets, binary relations, equivalence relations, partial ordering, minimum condition, and theorems equivalent to the axiom of choice. The text gives the definition of binary algebraic operation and the concepts of groups, groupoids, and semigroups. The book examines the parallelism between the theory of groups and the theory of rings; such examinations show the

  15. Generalized periodic and generalized Boolean rings

    Directory of Open Access Journals (Sweden)

    Howard E. Bell

    2001-01-01

    Full Text Available We prove that a generalized periodic, as well as a generalized Boolean, ring is either commutative or periodic. We also prove that a generalized Boolean ring with central idempotents must be nil or commutative. We further consider conditions which imply the commutativity of a generalized periodic, or a generalized Boolean, ring.

  16. Figure of Beijing ABP Showing up

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Last year, there were many good news from Beijing Advanced Business Park(ABP): on October 29, 2005, Xu Weiping, Chairman of the Board of ABP, was chosen as the"2005 Ten Major Chinese Administrative Person in News";On November 8,2005,CCIM (American Certified Commercial Investment Member) invited 40 world famous real estate investors to visit ABS and they showed will to cooperate; On November 22, 2005, Johnson Controls, Inc., one of World Top 500, signed the contract with Zhongguan Village Fengtai Garden that the headquarter of JCI energy administration China Branch will move to ABP to improve the energy administration and radiate all the nation; on December 10,2005, "CEO Salon" co-organized by Phoenix Satellite Television and ABP, was held in the meeting room of ABP, over 120CEOs met here to discuss the trend of China economic development and the development opportunities brought by 11th Five-Year Plan for enterprises.

  17. Lemurs and macaques show similar numerical sensitivity

    Science.gov (United States)

    Jones, Sarah M.; Pearson, John; DeWind, Nicholas K.; Paulsen, David; Tenekedjieva, Ana-Maria; Brannon, Elizabeth M.

    2013-01-01

    We investigated the precision of the approximate number system (ANS) in three lemur species (Lemur catta, Eulemur mongoz, and Eulemur macaco flavifrons), one Old World monkey species (Macaca mulatta) and humans (Homo sapiens). In Experiment 1, four individuals of each nonhuman primate species were trained to select the numerically larger of two visual arrays on a touchscreen. We estimated numerical acuity by modeling Weber fractions (w) and found quantitatively equivalent performance among all four nonhuman primate species. In Experiment 2, we tested adult humans in a similar procedure, and they outperformed the four nonhuman species but showed qualitatively similar performance. These results indicate that the ANS is conserved over the primate order. PMID:24068469

  18. Star Shows It Has The Right Stuff

    Science.gov (United States)

    2004-01-01

    Astronomers have used an observation by NASA's Chandra X-ray Observatory to make the best case yet that a star can be engulfed by its companion star and survive. This discovery will help astronomers better understand how closely coupled stars, and perhaps even stars and planets, evolve when one of the stars expands enormously in its red giant phase. The binary star system known as V471 Tauri comprises a white dwarf star (the primary) in a close orbit -- one thirtieth of the distance between Mercury and the Sun -- with a normal Sun-like star (the secondary). Chandra's data showed that the hot upper atmosphere of the secondary star has a deficit of carbon atoms relative to nitrogen atoms. "This deficit of carbon atoms is the first clear observational evidence that the normal star was engulfed by its companion in the past," according to Jeremy Drake of the Smithsonian Astrophysical Observatory in Cambridge, MA, who coauthored an article on V471 in The Astrophysical Journal Letters with Marek Sarna of the N. Copernicus Astronomical Center in Poland. The white dwarf star was once a star several times as massive as the Sun. Nuclear fusion reactions in the core of such a star convert carbon into nitrogen over a period of about a billion years. When the fuel in the core of the star is exhausted, the core collapses, triggering more energetic nuclear reactions that cause the star to expand and transform into a red giant before eventually collapsing to become a white dwarf. The carbon-poor material in the core of the red giant is mixed with outer part of the star, so its atmosphere shows a deficit of carbon, as compared with Sun-like stars. The X-ray spectra of a red giant star (top panel) and a Sun-like star (bottom panel) show the large difference in the peaks due to carbon atoms in the two stars. Theoretical calculations indicate that a red giant in a binary system can completely envelop its companion star and dramatically affect its evolution. During this common envelope

  19. Ancient bacteria show evidence of DNA repair

    DEFF Research Database (Denmark)

    Johnson, Sarah Stewart; Hebsgaard, Martin B; Christensen, Torben R

    2007-01-01

    Recent claims of cultivable ancient bacteria within sealed environments highlight our limited understanding of the mechanisms behind long-term cell survival. It remains unclear how dormancy, a favored explanation for extended cellular persistence, can cope with spontaneous genomic decay over......-term survival of bacteria sealed in frozen conditions for up to one million years. Our results show evidence of bacterial survival in samples up to half a million years in age, making this the oldest independently authenticated DNA to date obtained from viable cells. Additionally, we find strong evidence...... that this long-term survival is closely tied to cellular metabolic activity and DNA repair that over time proves to be superior to dormancy as a mechanism in sustaining bacteria viability....

  20. VLA's Sharpened Vision Shows Details of Still-Forming Star

    Science.gov (United States)

    2001-01-01

    available for routine astronomical observations last autumn. In late November, the scientists pointed the sharpened vision of the combined telescopes at an object called G192.16-3.82, more than 6,000 light-years distant in the constellation Orion. First observed in 1990, G192.16-3.82 was found to be a massive young star powering one of the largest stellar outflows -- extending more than 30 light years from end to end -- in the entire Milky Way Galaxy. Earlier observations showed the young star is surrounded by a large, rotating disk with a diameter greater than 1,000 times the Sun-Earth distance. Astronomers, however, believed that the outflow had to originate from a structure much smaller than this disk. The VLA-Pie Town system gave them their first glimpse of the suspected smaller structure, another disk slightly larger than our own Solar System containing enough gas and dust to make 20 Suns. In addition, they saw the inner portion of the outflow of material powered by that disk. The new observations also showed that the smaller disk probably is truncated by the gravitational pull of another, previously-unseen young star less massive than the first. Close to the larger protostar, the outflow is wide, covering an angle of about 40 degrees. "With smaller protostars, the outflow begins wide but then is narrowed down to a thin jet relatively close to its origin. However, when the protostar is more massive, the outflow tends to remain wide," Shepherd said. "We think that magnetic fields narrow down the flow from the smaller protostars. It's possible that when the flow contains much more mass, such as in this system, the magnetic fields may be just too weak in most cases to get this done," she said. "Our new observations now make it possible to test this idea by comparing computer simulations to what we see in the real universe," Shepherd said. The VLA is a system of 27 radio-telescope antennas distributed over the high desert west of Socorro, NM, in the shape of a giant "Y

  1. General(es) remisión de V. escuelas general(es).

    OpenAIRE

    2011-01-01

    [ES] Definición del término General(es) remisión de V. escuelas general(es). en el diccionario Dicter. [EN] Definition of the word General(es) remisión de V. escuelas general(es). in the dictionary Dicter.

  2. NASA GIBS Use in Live Planetarium Shows

    Science.gov (United States)

    Emmart, C. B.

    2015-12-01

    The American Museum of Natural History's Hayden Planetarium was rebuilt in year 2000 as an immersive theater for scientific data visualization to show the universe in context to our planet. Specific astrophysical movie productions provide the main daily programming, but interactive control software, developed at AMNH allows immersive presentation within a data aggregation of astronomical catalogs called the Digital Universe 3D Atlas. Since 2006, WMS globe browsing capabilities have been built into a software development collaboration with Sweden's Linkoping University (LiU). The resulting Uniview software, now a product of the company SCISS, is operated by about fifty planetariums around that world with ability to network amongst the sites for global presentations. Public presentation of NASA GIBS has allowed authoritative narratives to be presented within the range of data available in context to other sources such as Science on a Sphere, NASA Earth Observatory and Google Earth KML resources. Specifically, the NOAA supported World Views Network conducted a series of presentations across the US that focused on local ecological issues that could then be expanded in the course of presentation to national and global scales of examination. NASA support of for GIBS resources in an easy access multi scale streaming format like WMS has tremendously enabled particularly facile presentations of global monitoring like never before. Global networking of theaters for distributed presentations broadens out the potential for impact of this medium. Archiving and refinement of these presentations has already begun to inform new types of documentary productions that examine pertinent, global interdependency topics.

  3. The great American medicine show revisited.

    Science.gov (United States)

    Tomes, Nancy

    2005-01-01

    Since the late 1800s, changes in the advertising and marketing of medicinal drugs have produced heated debates in the United States. With the emergence of the modern prescription drug between 1938 and 1951, concerns that once focused primarily on patients' use of over-the-counter drugs were broadened to include physicians and their "doctors' drugs" as well. The medical profession's growing control over their patients' drug choices inevitably heightened the scrutiny of their own performance as consumers. Although deeply divided over issues of the patient's role in medical decision making, consumer activists and physician reformers expressed similar concerns about the impact of aggressive pharmaceutical marketing and advertising on the doctor-patient relationship, and starting in the late 1950s they employed strikingly similar strategies to counter the new corporate "medicine show." Yet their efforts to promote a more rational use of prescription drugs have usually been too little and too late to offset the effectiveness of pharmaceutical advertising and mar-keting activities.

  4. Tetrahydrobiopterin shows chaperone activity for tyrosine hydroxylase.

    Science.gov (United States)

    Thöny, Beat; Calvo, Ana C; Scherer, Tanja; Svebak, Randi M; Haavik, Jan; Blau, Nenad; Martinez, Aurora

    2008-07-01

    Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of catecholamine neurotransmitters. Primary inherited defects in TH have been associated with l-DOPA responsive and non-responsive dystonia and infantile parkinsonism. In this study, we show that both the cofactor (6R)-l-erythro-5,6,7,8-tetrahydrobiopterin (BH(4)) and the feedback inhibitor and catecholamine product dopamine increase the kinetic stability of human TH isoform 1 in vitro. Activity measurements and synthesis of the enzyme by in vitro transcription-translation revealed a complex regulation by the cofactor including both enzyme inactivation and conformational stabilization. Oral BH(4) supplementation to mice increased TH activity and protein levels in brain extracts, while the Th-mRNA level was not affected. All together our results indicate that the molecular mechanisms for the stabilization are a primary folding-aid effect of BH(4) and a secondary effect by increased synthesis and binding of catecholamine ligands. Our results also establish that orally administered BH(4) crosses the blood-brain barrier and therapeutic regimes based on BH(4) supplementation should thus consider the effect on TH. Furthermore, BH(4) supplementation arises as a putative therapeutic agent in the treatment of brain disorders associated with TH misfolding, such as for the human TH isoform 1 mutation L205P.

  5. The earliest published electrocardiogram showing ventricular preexcitation.

    Science.gov (United States)

    Von Knorre, Georg H

    2005-03-01

    When in 1930, Wolff, Parkinson, and White published what is today known as the WPW, or preexcitation syndrome, they, and subsequently others, found few comparable cases in the preceding literature. Among these the report of Cohn and Fraser, published in 1913, was the earliest. However, another even earlier documentation in a 1909 article by Hoffmann escaped notice till now. The ECG of a patient with paroxysmal tachycardia reveals a short PR interval and a delta-wave-induced widening of the QRS complex, even though the reproduced tachycardia was not preexcitation related. The interpretation of this poorly reproduced ECG can be confirmed by another and more detailed description of the patient in an electrocardiography textbook published in 1914 by the same author. Thus, the earliest publication of an ECG showing ventricular preexcitation now can be dated back to 1909. Moreover, the Hoffmann monograph contains two additional examples of the WPW syndrome not noticed until now. All three cases published by Hoffmann had their first ECG recordings in 1912 or earlier.

  6. Ribavirin shows immunomodulatory effects on activated microglia.

    Science.gov (United States)

    Savic, Danijela; Stojiljkovic, Mirjana; Lavrnja, Irena; Parabucki, Ana; Bjelobaba, Ivana; Nedeljkovic, Nadezda; Herdegen, Thomas; Pekovic, Sanja

    2014-12-01

    Abstract Ribavirin (RBV) is synthetic purine nucleoside analogue, licensed as anti-viral drug that displays immunomodulatory actions on various immune cells. Our previous ex vivo studies have demonstrated immunosuppressive effects of RBV on reactive T-lymphocytes in experimental autoimmune encephalomyelitis. Here, we examined the effects of RBV on inflammatory response of microglia. RBV potency to down-regulate microglia inflammatory response was assessed by measuring microglia cell body size, and the production of nitric oxide (NO) and pro- and anti-inflammatory cytokines. RBV exerted cytotoxic effects on LPS-stimulated microglia, leaving non-stimulated microglia unaffected. The exposure of activated microglia to RBV led to: decrease in the level of NO as a result of decreased cell number, lower average cell surface, the reduction of membrane ruffling, the suppression of interleukin-6 release and promoted interleukin-10 production. On the other hand, RBV promoted LPS-induced interleukin-1 beta release. Our results imply that RBV is a complex immunomodulator showing both anti- and pro-inflammatory effects on activated microglia.

  7. Generalized gravity from modified DFT

    CERN Document Server

    Sakatani, Yuho; Yoshida, Kentaroh

    2016-01-01

    Recently, generalized equations of type IIB supergravity have been derived from the requirement of classical kappa-symmetry of type IIB superstring theory in the Green-Schwarz formulation. These equations are covariant under generalized T-duality transformations and hence one may expect a formulation similar to double field theory (DFT). In this paper, we consider a modification of the DFT equations of motion by relaxing a condition for the generalized covariant derivative with an extra generalized vector. In this modified double field theory (mDFT), we show that the flatness condition of the modified generalized Ricci tensor leads to the NS-NS part of the generalized equations of type IIB supergravity. In particular, the extra vector fields appearing in the generalized equations correspond to the extra generalized vector in mDFT. We also discuss duality symmetries and a modification of the string charge in mDFT.

  8. Generalized uncertainty principles

    CERN Document Server

    Machluf, Ronny

    2008-01-01

    The phenomenon in the essence of classical uncertainty principles is well known since the thirties of the last century. We introduce a new phenomenon which is in the essence of a new notion that we introduce: "Generalized Uncertainty Principles". We show the relation between classical uncertainty principles and generalized uncertainty principles. We generalized "Landau-Pollak-Slepian" uncertainty principle. Our generalization relates the following two quantities and two scaling parameters: 1) The weighted time spreading $\\int_{-\\infty}^\\infty |f(x)|^2w_1(x)dx$, ($w_1(x)$ is a non-negative function). 2) The weighted frequency spreading $\\int_{-\\infty}^\\infty |\\hat{f}(\\omega)|^2w_2(\\omega)d\\omega$. 3) The time weight scale $a$, ${w_1}_a(x)=w_1(xa^{-1})$ and 4) The frequency weight scale $b$, ${w_2}_b(\\omega)=w_2(\\omega b^{-1})$. "Generalized Uncertainty Principle" is an inequality that summarizes the constraints on the relations between the two spreading quantities and two scaling parameters. For any two reason...

  9. Effect of larval growth conditions on adult body mass and long-distance flight endurance in a wood-boring beetle: Do smaller beetles fly better?

    Science.gov (United States)

    Brown, Stav; Soroker, Victoria; Ribak, Gal

    2017-04-01

    The tropical fig borer, Batocera rufomaculata De Geer, is a large beetle that is a pest on a number of fruit trees, including fig and mango. Adults feed on the leaves and twigs and females lay their eggs under the bark of the tree. The larvae bore into the tree trunk, causing substantial damage that may lead to the collapse and death of the host tree. We studied how larval development under inferior feeding conditions (experienced during development in dying trees) affects flight endurance in the adult insect. We grew larvae either in their natural host or on sawdust enriched with stale fig tree twigs. Flight endurance of the adults was measured using a custom-built flight-mill. Beetles emerging from the natural host were significantly larger but flew shorter distances than beetles reared on less favourable substrates. There was no difference in the allometric slope of wing area with body mass between the beetles groups; however flight muscle mass scaled with total body mass with an exponent significantly lower than 1.0. Hence, smaller beetles had proportionally larger flight muscles. These findings suggest that beetles that developed smaller as a result from poor nutritional conditions in deteriorating hosts, are better equipped to fly longer distances in search of a new host tree.

  10. Computing excess functions of ionic solutions: the smaller-ion shell model versus the primitive model. 2. Ion-size parameters.

    Science.gov (United States)

    Fraenkel, Dan

    2015-01-13

    A recent Monte Carlo (MC) simulation study of the primitive model (PM) of ionic solutions ( Abbas, Z. et al. J. Phys. Chem. B 2009 , 113 , 5905 ) has resulted in an extensive "mapping" of real aqueous solutions of 1-1, 2-1, and 3-1 binary electrolytes and a list of "recommended ionic radii" for many ions. For the smaller cations, the model-experiment fitting process gave much larger radii than the respective crystallographic radii, and those cations were therefore claimed to be hydrated. In Part 1 (DOI 10.1021/ct5006938 ) of the present work, the above study for the unrestricted PM - dubbed MC-UPM - has been confronted with the Smaller-ion Shell (SiS) treatment ( Fraenkel, D. Mol. Phys. 2010 , 108 , 1435 ), or "DH-SiS", by comparing the range and quality of model-experiment fits of the mean ionic activity coefficient as a function of ionic concentration. Here I compare the ion-size parameters (ISPs) of "best fit" of the two models and argue that since ISPs derived from DH-SiS are identical with (or close to) crystallographic or thermochemical ionic diameters for both cations and anions, and they do not depend on the counterion - they are more reliable, as physicochemical entities, than the PM-derived "recommended ionic radii".

  11. MRI shows clodronate-liposomes attenuating liverinjuryinratswithsevereacutepancreatitis

    Institute of Scientific and Technical Information of China (English)

    Jian-Xin Zhang; Sheng-Chun Dang; Yong Zhang; Xin Sha; Li-Rong Zhang; Chuan-She Wei; Min Chen; De-Li Jiang

    2010-01-01

    BACKGROUND: Studies have revealed that macrophages play an important role in the development of severe acute pancreatitis (SAP). Activated macrophages can lead to a systemic inlfammatory response, induce lipid peroxidation, impair membrane structure, result in injury to the liver and the other extrahepatic organs, and eventually result in multiple organ dysfunction syndrome by promoting excessive secretion of cytokines. Liver injury can further aggravate the systemic inlfammatory response and increase mortality by affecting the metabolism of toxins and the release of excessive inlfammatory mediators. Clodronate is a synthetic bisphosphonate, which is often used for treating bone changes caused by osteoporosis and other factors. In the current study, we created liposomes containing superparamagnetic iron oxide particles (SPIOs) for macrophage labeling and magnetic resonance imaging, using a novel method that can bind the clodronate to induce apoptosis and deplete macrophages. METHODS: Superparamagnetic Fe3O4 nanoparticles were prepared by chemical coprecipitation. SPIO-containing liposomes and SPIO-clodronate-containing liposomes were prepared by the thin iflm method. SAP models were prepared by injection of sodium taurocholate (2 ml/kg body weight) into the subcapsular space of the pancreas. Sprague-Dawley rats were randomly divided into a control group, a SAP plus SPIO-liposome group, and a SAP plus SPIO-clodronate-containing group. Two and six hours after SAP models were available, T2-weighted MRI scans (in the same plane) of the livers of rats in each group were performed. At the end of the scans, 2 ml of blood was taken from the superior mesenteric vein to measure the levels of serum amylase, ALT, AST, TNF-α, and IL-6. Pathological changes in the liver and pancreas were assessed. RESULTS: Transmission electron microscopy showed that the liposomes had a uniform size. No pathological changes in the pancreata of rats in the control group were noted. The

  12. Highly reflective reasoners show no signs of belief inhibition.

    Science.gov (United States)

    Svedholm-Häkkinen, Annika M

    2015-01-01

    The processes underlying individual differences in reasoning performance are not entirely understood. What do people who do well on reasoning tasks where beliefs and logic conflict do differently from other people? Because abundant evidence shows that even poorer reasoners detect these conflicts, it has been suggested that individual differences in reasoning performance arise from inhibition failures later in the reasoning process. The present paper argues that a minority of highly skilled reasoners may deviate from this general reasoning process from an early stage. Two studies investigated signs of belief inhibition using a lexical access paradigm (Study 1) and a negative priming paradigm (Study 2). Study 1 showed that while other people exhibited signs of belief inhibition following a belief-logic conflict, people with the highest disposition for cognitive reflection did not. In Study 2, this finding was replicated and similar results were also obtained when comparing groups with higher and lower general cognitive ability. Two possible explanations are discussed. The reasoners with a highly reflective cognitive style or high general cognitive ability may have engaged and inhibited belief processing but if so, they may have been exceptionally efficient at recovering from it, wherefore no belief inhibition effects were found. An alternative account is that these reasoners started Type 2 processing directly, without first engaging in and then inhibiting belief-based processing. Under either explanation, the results indicate that individual differences in reasoning may partly arise from differences that occur early in the reasoning process.

  13. The Phase Space Elementary Cell in Classical and Generalized Statistics

    Directory of Open Access Journals (Sweden)

    Piero Quarati

    2013-10-01

    Full Text Available In the past, the phase-space elementary cell of a non-quantized system was set equal to the third power of the Planck constant; in fact, it is not a necessary assumption. We discuss how the phase space volume, the number of states and the elementary-cell volume of a system of non-interacting N particles, changes when an interaction is switched on and the system becomes or evolves to a system of correlated non-Boltzmann particles and derives the appropriate expressions. Even if we assume that nowadays the volume of the elementary cell is equal to the cube of the Planck constant, h3, at least for quantum systems, we show that there is a correspondence between different values of h in the past, with important and, in principle, measurable cosmological and astrophysical consequences, and systems with an effective smaller (or even larger phase-space volume described by non-extensive generalized statistics.

  14. A general relativistic signature in the galaxy bispectrum

    CERN Document Server

    Umeh, Obinna; Maartens, Roy; Clarkson, Chris

    2016-01-01

    Next-generation galaxy surveys will increasingly rely on the galaxy bispectrum to improve cosmological constraints, especially on primordial non-Gaussianity. A key theoretical requirement that remains to be developed is the analysis of general relativistic effects on the bispectrum, which arise from observing galaxies on the past lightcone. Here we compute for the first time all the local relativistic corrections to the bispectrum, from Doppler, gravitational potential and higher-order effects. For the galaxy bispectrum, the problem is much more complex than for the power spectrum, since we need the lightcone corrections at second order. Mode-coupling contributions at second order mean that relativistic corrections can be non-negligible at smaller scales than in the case of the power spectrum. In a primordial Gaussian universe, we show that the relativistic bispectrum for a moderately squeezed shape can differ from the Newtonian prediction by $\\sim 30\\%$ when the short modes are at the equality scale. For the...

  15. Complete synchronization and generalized synchronization of one-way coupled time-delay systems.

    Science.gov (United States)

    Zhan, Meng; Wang, Xingang; Gong, Xiaofeng; Wei, G W; Lai, C-H

    2003-09-01

    The complete synchronization and generalized synchronization (GS) of one-way coupled time-delay systems are studied. We find that GS can be achieved by a single scalar signal, and its synchronization threshold for different delay times shows the parameter resonance effect, i.e., we can obtain stable synchronization at a smaller coupling if the delay time of the driven system is chosen such that it is in resonance with the driving system. Near chaos synchronization, the desynchronization dynamics displays periodic bursts with the period equal to the delay time of the driven system. These features can be easily applied to the recovery of time-delay systems.

  16. Generalized Lindley Distribution

    Directory of Open Access Journals (Sweden)

    H. Zakerzadeh

    2009-06-01

    Full Text Available In this paper, we introduce a three–parameter generalization of the Lindley distribution. This includes as special cases the exponential and gamma distributions. The distribution exhibits decreasing, increasing and bathtub hazard rate depending on its parameters. We study various properties of the new distribution and provide numerical examples to show the flexibility of the model. We also derive a bivariate version of the proposed distribution.

  17. Generalization of Hasimoto's transformation

    CERN Document Server

    Molitor, Mathieu

    2012-01-01

    In this paper, we generalize the famous Hasimoto's transformation by showing that the dynamics of a closed unidimensional vortex filament embedded in a three-dimensional manifold of constant curvature gives rise under Hasimoto's transformation to the non-linear Schrodinger equation. We also give a natural interpretation of the function \\psi introduced by Hasimoto in terms of moving frames associated to a natural complex bundle over the filament.

  18. Leadership and cooperation at the general medicine department of LMU Munich: Good grades despite difficult conditions.

    Science.gov (United States)

    Schelling, Jörg; Braun, Susanne

    2011-01-01

    The relevance of general medicine at German universities will increase over the next few years. Consequently, the discussion of teaching content and even more the improvement of the structures within the still small and dependent departments of general medicine are of major importance. The example of our department at LMU Munich shows which challenges for leadership and cooperation result from lack of financial and personnel structure. The project "cooperation culture" that the department has conducted in collaboration with the LMU Center for Leadership and People Management is presented as a means to promote leadership and cooperation. This project can serve as an inspiration for the coordinators of smaller departments of general medicine at other German universities that are also striving to improve their structure and their position within the university.

  19. The generalized Fubini instanton

    Energy Technology Data Exchange (ETDEWEB)

    Yurova, A.A. [Department of Higher Mathematics, Kaliningrad State Technical University, 236000, Soviet Avenue 1, Kaliningrad (Russian Federation)], E-mail: yurov@freemail.ru; Yurov, A.V. [Department of Theoretical Physics, Russian State University of I. Kant, 236041, Aleksandra Nevskogo street 14, Kaliningrad (Russian Federation)], E-mail: artyom_yurov@mail.ru

    2008-06-02

    We show that (1+2) nonlinear Klein-Gordon equation with negative coupling admits an exact solution which appears to be the linear superposition of the plane wave and the nonsingular rational soliton. We show that the same approach allows to construct the solution of similar properties for the Euclidean {phi}{sup 4} model with broken symmetry. Interestingly, this regular solution will be of instanton type only in the D{<=}5 Euclidean space. Thus one can use the generalized Fubini instantons (in quantum cosmology for example) only for the case of the single infinite extra dimension.

  20. A Selection for Assembly Reveals That a Single Amino Acid Mutant of the Bacteriophage MS2 Coat Protein Forms a Smaller Virus-like Particle.

    Science.gov (United States)

    Asensio, Michael A; Morella, Norma M; Jakobson, Christopher M; Hartman, Emily C; Glasgow, Jeff E; Sankaran, Banumathi; Zwart, Peter H; Tullman-Ercek, Danielle

    2016-09-14

    Virus-like particles are used to encapsulate drugs, imaging agents, enzymes, and other biologically active molecules in order to enhance their function. However, the size of most virus-like particles is inflexible, precluding the design of appropriately sized containers for different applications. Here, we describe a chromatographic selection for virus-like particle assembly. Using this selection, we identified a single amino acid substitution to the coat protein of bacteriophage MS2 that mediates a uniform switch in particle geometry from T = 3 to T = 1 icosahedral symmetry. The resulting smaller particle retains the ability to be disassembled and reassembled in vitro and to be chemically modified to load cargo into its interior cavity. The pair of 27 and 17 nm MS2 particles will allow direct examination of the effect of size on function in established applications of virus-like particles, including drug delivery and imaging.

  1. Computational Procedure to Replace a Bulky Flywheel for a Process Machine by a Combination of Appropriately Controlled VVVf Drive for Motor and a Smaller Flywheel

    Directory of Open Access Journals (Sweden)

    Manjusha Viraj Palandurkar

    2012-06-01

    Full Text Available Process machines with tougher duty cycles are subjected to wide fluctuations in load torque. These often need a bulky flywheel for torque equalization with disadvantages of torsional oscillations. This results into fatigue of mechanical power transmission elements leading subsequently to equipment failure causing prolonged and frequent down time which results into financial losses. A simpler acceptable alternative is proposed in this article. Suitably monitored VVVf drives and low moment of inertia offer a much better alternative, for improving the system behavior drastically. Controlling the power input to the main electric drive with VVVf technique can generate almost matching demand torque characteristics. A much smaller flywheel is able to improve the accuracy to have better torque matching. This paper deals with estimation of necessary moment of inertia of flywheel in view of minimizing the difference in the required demand torque characteristics and the generated supply torque characteristics.

  2. New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients

    Directory of Open Access Journals (Sweden)

    Kim YK

    2017-09-01

    Full Text Available Yu Kyong Kim,1 Anhye Kim,1,2 Shin Jung Park,3 Howard Lee1,4 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Clinical Trial Center, Ajou University Medical Center, Suwon, 3Research Institute, Chong Kun Dang Pharmaceutical Corp, Yongin, 4Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Suwon, Republic of Korea Abstract: To evaluate the pharmacokinetic (PK and tolerability profiles of a new tablet formulation of tacrolimus and its interindividual variability (IIV in the systemic exposure, and to compare them with those of the conventional capsule formulation, a randomized, open-label, two-treatment, two-period, two-sequence, crossover study was performed in 47 healthy males. The capsule or tablet formulation of tacrolimus was orally administered, and serial blood samples were collected up to 96 hours after dosing. Whole-blood tacrolimus concentration was determined using liquid chromatography–tandem mass spectrometry. The maximum whole-blood tacrolimus concentration (Cmax and the area under the whole-blood tacrolimus concentration–time curve from 0 hour to the last quantifiable concentration (AUClast were compared between the two formulations. The similarity factor (f2 of the in vitro dissolution profiles was calculated. The geometric mean ratio (90% confidence interval of tablet to capsule was 0.9680 (0.8873–1.0560 and 1.0322 (0.9359–1.1385 for Cmax and AUClast, respectively. The IIV of Cmax and AUClast of the tablet was smaller than the capsule. The f2 values were >50 in all media. Both formulations were well tolerated. Thus, the tablet formulation of tacrolimus has smaller IIV in the systemic exposure than capsule, while having comparable PK and tolerability profiles, which may render it as a better treatment option for organ transplant patients. Keywords: new formulation, incrementally

  3. Ultrasound-Guided Fine-Needle Aspiration Biopsy of Thyroid Nodules Smaller Than 5 mm in the Maximum Diameter: Assessment of Efficacy and Pathological Findings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dong Wook; Park, Auh Whan; Lee, Eun Joo; Choo, Hye Jung; Kim, Sang Hyo; Lee, Sang Hyub; Eom, Jae Wook [Busan Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of)

    2009-10-15

    The aim of this study was to determine the efficacy of the use of an ultrasound-guided fine-needle aspiration biopsy (US-FNAB) to diagnose thyroid nodules smaller than 5 mm in the maximum diameter and to evaluate pathological findings of small thyroid malignancies. From May 2007 to April 2008, we evaluated the findings of US-FNABs of small thyroid nodules less than 5 mm in the maximum diameter. The cytopathological findings were retrospectively reviewed and the diagnostic performance of the use of an US-FNAB was examined in all patients. Of 201 small thyroid nodules in 180 patients, there were 162 adequate specimens (81%). Among 180 patients, 75 patients underwent thyroid surgery and 50 malignant and 33 benign nodules were identified based on a pathological examination. All small malignant thyroid nodules were identified as papillary thyroid microcarcinomas (PTMCs). There were 34 (55%) true positive, 0 (0%) false positive, 23 (37%) true negative and five (8%) false negative results for malignancy after performing a first US-FNAB in 62 surgically confirmed nodules. The sensitivity (87%), specificity (100%), positive predictive value (100%), negative predictive value (82%), accuracy (92%), false positive rate (0%) and false negative rate (8%) for an US-FNAB were determined. In 23 patients with a primary PTMC, capsular invasion (9%, 2 of 23), a perithyroidal lymph node metastasis (30%, 7 of 23), the rate of multifocality (9%, 2 of 23) and bilaterality (4%, 1 of 23) were also determined. An US-FNAB of thyroid nodules smaller than 5 mm in the maximum diameter is an effective diagnostic procedure.

  4. General form of quantum evolution

    CERN Document Server

    Chruscinski, Dariusz

    2010-01-01

    We propose a complete treatment of a local in time dynamics of open quantum systems. In this approach Markovian evolution turns out to be a special case of a general non-Markovian one. We provide a general representation of the local generator which generalizes well known Lindblad representation for the Markovian dynamics. It shows that the structure of non-Markovian generators is highly intricate and the problem of their classification is still open. Simple examples illustrate our approach.

  5. Chronic pulmonary thromboembolism pathologically showing homogeneous cellular alveolitis.

    Science.gov (United States)

    Miwa, Seiichi; Shirai, Masahiro; Kobayashi, Shigeru; Kaida, Yusuke; Suda, Takafumi; Hayakawa, Hiroshi; Chida, Kingo

    2011-01-01

    A 60-year-old man was admitted to our hospital complaining of general malaise. Examination of arterial blood gases on room air revealed hypoxia. Pulmonary function test showed restrictive abnormality. Chest high-resolution CT showed diffuse mosaic attenuation without evident pulmonary artery abnormality on contrast chest CT. Based on these findings, interstitial pneumonia or chronic pulmonary thromboembolism was suspected. The findings of bronchoalveolar lavage revealed 4.4×10(5) cells/mL, including 89.6% macrophages, 9.4% lymphocytes, and 1.0% neutrophils. TBLB showed marked alveolitis. Moreover video-assisted thoracoscopic surgical biopsy was performed. Biopsies of the lung specimen showed focal infarct with surrounding mild mononuclear cell infiltrates (homogenous cellular alveolitis). (99m)Tc pulmonary perfusion and (81m)Kr ventilation scintigraphy showed V/Q mismatch. Furthermore, pulmonary angiography also revealed inadequate artery flow corresponding to the mismatch area of scintigraphy. Collagen vascular diseases and abnormality of coagulation factors were not detected. Multiple perfusion defects persisted for more than 6 months. Thus, finally the patient was diagnosed with chronic pulmonary thromboembolism, pathologically showing homogenous cellular alveolitis.

  6. Learning View Generalization Functions

    CERN Document Server

    Breuel, Thomas M

    2007-01-01

    Learning object models from views in 3D visual object recognition is usually formulated either as a function approximation problem of a function describing the view-manifold of an object, or as that of learning a class-conditional density. This paper describes an alternative framework for learning in visual object recognition, that of learning the view-generalization function. Using the view-generalization function, an observer can perform Bayes-optimal 3D object recognition given one or more 2D training views directly, without the need for a separate model acquisition step. The paper shows that view generalization functions can be computationally practical by restating two widely-used methods, the eigenspace and linear combination of views approaches, in a view generalization framework. The paper relates the approach to recent methods for object recognition based on non-uniform blurring. The paper presents results both on simulated 3D ``paperclip'' objects and real-world images from the COIL-100 database sho...

  7. 14 CFR Section 4 - General

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false General Section 4 Section 4 Aeronautics and... Section 4 General (a) The balance sheet accounts are designed to show the financial condition of the air... prescribed in this system of accounts for each air carrier group are set forth in Section 3, Chart of Balance...

  8. Neuro-Behcet's disease showing severe atrophy of the cerebrum.

    Science.gov (United States)

    Miyakawa, T; Murayama, E; Deshimaru, M; Shikai, I; Kozuma, S

    1976-03-15

    A 38-year-old female died 6 years after the onset of what was, clinically and histopathologically, consistent with neuro-Behcet's disease. Pathologically the cerebrum showed severe atrophy. The main changes were observed in the grey and white matter, the diencephalon and the basal ganglia by light microscopy. All these changes originated in softenings around blood vessels, especially small vessels or capillaries. These foci fused together to form large regions of softening. Glial or mesenchymal reactions were minimal. In the white matter there was slight perivascular-infiltration, mainly consisting of lymphocytes. In view of these findings, it is suggested that these changes were caused by an allergic vasculitis. The present case of Neuro-Behcet's disease is the first one showing general atrophy of the cerebrum. It is very important in relation to demyelinating encephalitis.

  9. Face and body recognition show similar improvement during childhood.

    Science.gov (United States)

    Bank, Samantha; Rhodes, Gillian; Read, Ainsley; Jeffery, Linda

    2015-09-01

    Adults are proficient in extracting identity cues from faces. This proficiency develops slowly during childhood, with performance not reaching adult levels until adolescence. Bodies are similar to faces in that they convey identity cues and rely on specialized perceptual mechanisms. However, it is currently unclear whether body recognition mirrors the slow development of face recognition during childhood. Recent evidence suggests that body recognition develops faster than face recognition. Here we measured body and face recognition in 6- and 10-year-old children and adults to determine whether these two skills show different amounts of improvement during childhood. We found no evidence that they do. Face and body recognition showed similar improvement with age, and children, like adults, were better at recognizing faces than bodies. These results suggest that the mechanisms of face and body memory mature at a similar rate or that improvement of more general cognitive and perceptual skills underlies improvement of both face and body recognition.

  10. General Information about Pituitary Tumors

    Science.gov (United States)

    ... Tumors Treatment Pituitary Tumors Treatment (PDQ®)–Patient Version General Information About Pituitary Tumors Go to Health Professional ... by many other glands in the body. Enlarge Anatomy of the inside of the brain, showing the ...

  11. General Information about Prostate Cancer

    Science.gov (United States)

    ... Screening Research Prostate Cancer Treatment (PDQ®)–Patient Version General Information About Prostate Cancer Go to Health Professional ... fluid that is part of the semen . Enlarge Anatomy of the male reproductive and urinary systems, showing ...

  12. Beyond generalized Proca theories

    CERN Document Server

    Heisenberg, Lavinia; Tsujikawa, Shinji

    2016-01-01

    We consider higher-order derivative interactions beyond second-order generalized Proca theories that propagate only the three desired polarizations of a massive vector field besides the two tensor polarizations from gravity. These new interactions follow the similar construction criteria to those arising in the extension of scalar-tensor Horndeski theories to Gleyzes-Langlois-Piazza-Vernizzi (GLPV) theories. On the maximally symmetric space-time, we perform the Hessian and Hamiltonian analysis and show the presence of a second-class constraint that removes the would-be ghost associated with the temporal component of the vector field. Furthermore, we study the behavior of linear perturbations on top of the homogeneous and isotropic cosmological background in the presence of a matter perfect fluid and find the same number of propagating degrees of freedom as in generalized Proca theories. Moreover, we obtain the conditions for the avoidance of ghosts and Laplacian instabilities of tensor, vector, and scalar per...

  13. Measuring mimicry: general corticospinal facilitation during observation of naturalistic behaviour.

    Science.gov (United States)

    van Schaik, J E; Sacheli, L M; Bekkering, H; Toni, I; Aglioti, S M

    2017-07-01

    Mimicry of others' postures and behaviours forms an implicit yet indispensable component of social interactions. However, whereas numerous behavioural studies have investigated the occurrence of mimicry and its social sensitivity, the underlying neurocognitive mechanisms remain elusive. In this study, single-pulse transcranial magnetic stimulation was used to measure corticospinal facilitation during a naturalistic behaviour observation task adapted from the behavioural mimicry literature. Motor evoked potentials (MEPs) in participants' right hands were measured as they observed stimulus videos of a confederate describing photographs. MEPs were recorded while confederates were and were not carrying out hand and leg behaviours that also differed in spatial extent (i.e. large behaviours: face rubbing and leg crossing; small behaviours: finger tapping and foot bouncing). Importantly, the cover task instructions did not refer to the behaviours but instead required participants to focus on the confederates' photograph descriptions in order to later perform a recognition test. A general arousal effect was found, with higher MEPs during stimulus video observation than during a fixation-cross baseline, regardless of whether or not the confederate was carrying out a behaviour at the time of the pulse. When controlling for this general arousal effect, results showed that MEPs during observation of the larger two behaviours were significantly higher than the smaller two behaviours, irrespective of effector. Thus, using a controlled yet naturalistic paradigm, this study suggests that general sensorimotor arousal during social interactions could play a role in implicit behavioural mimicry. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  14. Non-adiabatic oscillations of compact stars in general relativity

    CERN Document Server

    Gualtieri, L; Miniutti, G

    2004-01-01

    We have developed a formalism to study non-adiabatic, non-radial oscillations of compact stars in the frequency domain including the effects of thermal diffusion in a general relativistic framework. When a general equation of state depending on temperature is used, the perturbations of the fluid result in heat flux which is coupled with the spacetime geometry through the Einstein field equations. Our results show that the frequency of the first pressure (p) and gravity (g) oscillation modes is significantly affected by thermal diffusion, while that of the fundamental (f) mode is basically unaltered due to the global nature of that oscillation. The damping time of the oscillations is generally much smaller than in the adiabatic case (more than two orders of magnitude for the p- and g-modes) reflecting the effect of thermal dissipation. Both the isothermal and adiabatic limits are recovered in our treatment and we study in more detail the intermediate regime. Our formalism finds its natural astrophysical applic...

  15. Hyperuniformity and its generalizations.

    Science.gov (United States)

    Torquato, Salvatore

    2016-08-01

    Disordered many-particle hyperuniform systems are exotic amorphous states of matter that lie between crystal and liquid: They are like perfect crystals in the way they suppress large-scale density fluctuations and yet are like liquids or glasses in that they are statistically isotropic with no Bragg peaks. These exotic states of matter play a vital role in a number of problems across the physical, mathematical as well as biological sciences and, because they are endowed with novel physical properties, have technological importance. Given the fundamental as well as practical importance of disordered hyperuniform systems elucidated thus far, it is natural to explore the generalizations of the hyperuniformity notion and its consequences. In this paper, we substantially broaden the hyperuniformity concept along four different directions. This includes generalizations to treat fluctuations in the interfacial area (one of the Minkowski functionals) in heterogeneous media and surface-area driven evolving microstructures, random scalar fields, divergence-free random vector fields, and statistically anisotropic many-particle systems and two-phase media. In all cases, the relevant mathematical underpinnings are formulated and illustrative calculations are provided. Interfacial-area fluctuations play a major role in characterizing the microstructure of two-phase systems (e.g., fluid-saturated porous media), physical properties that intimately depend on the geometry of the interface, and evolving two-phase microstructures that depend on interfacial energies (e.g., spinodal decomposition). In the instances of random vector fields and statistically anisotropic structures, we show that the standard definition of hyperuniformity must be generalized such that it accounts for the dependence of the relevant spectral functions on the direction in which the origin in Fourier space is approached (nonanalyticities at the origin). Using this analysis, we place some well-known energy

  16. Hyperuniformity and its generalizations

    Science.gov (United States)

    Torquato, Salvatore

    2016-08-01

    Disordered many-particle hyperuniform systems are exotic amorphous states of matter that lie between crystal and liquid: They are like perfect crystals in the way they suppress large-scale density fluctuations and yet are like liquids or glasses in that they are statistically isotropic with no Bragg peaks. These exotic states of matter play a vital role in a number of problems across the physical, mathematical as well as biological sciences and, because they are endowed with novel physical properties, have technological importance. Given the fundamental as well as practical importance of disordered hyperuniform systems elucidated thus far, it is natural to explore the generalizations of the hyperuniformity notion and its consequences. In this paper, we substantially broaden the hyperuniformity concept along four different directions. This includes generalizations to treat fluctuations in the interfacial area (one of the Minkowski functionals) in heterogeneous media and surface-area driven evolving microstructures, random scalar fields, divergence-free random vector fields, and statistically anisotropic many-particle systems and two-phase media. In all cases, the relevant mathematical underpinnings are formulated and illustrative calculations are provided. Interfacial-area fluctuations play a major role in characterizing the microstructure of two-phase systems (e.g., fluid-saturated porous media), physical properties that intimately depend on the geometry of the interface, and evolving two-phase microstructures that depend on interfacial energies (e.g., spinodal decomposition). In the instances of random vector fields and statistically anisotropic structures, we show that the standard definition of hyperuniformity must be generalized such that it accounts for the dependence of the relevant spectral functions on the direction in which the origin in Fourier space is approached (nonanalyticities at the origin). Using this analysis, we place some well-known energy

  17. Multiparticle Generalization of Teleportation

    Institute of Scientific and Technical Information of China (English)

    YANG Chui-Ping; GUO Guang-Can

    2000-01-01

    A scheme for teleporting an unknown quantum state of many particles is proposed. The scheme operates es sentially by prearranging the sharing of an Einstein-Podolsky-Rosen-correlated pair of particles every time. We show that after performing a series of Bell-state measurements and single-particle unitary transformations, the unknown state of many particles, which was destroyed at one place, can be reconstructed at another place. Our scheme is actually obtained by generalizing an earlier scheme of Bennett et al. [Phys. Rev. Lett. 70 (1993) 1895; 76 (1996) 722] known as quantum teleportation to the multiparticle case.

  18. Generalized Superfield Lagrangian Quantization

    CERN Document Server

    Lavrov, P M; Moshin, P Y

    2002-01-01

    We consider an extension of the gauge-fixing procedure in the framework of the Lagrangian superfield BRST and BRST-antiBRST quantization schemes for arbitrary gauge theories, taking into account the possible ambiguity in the choice of the superfield antibracket. We show that this ambiguity is fixed by the algebraic properties of the antibracket and the form of the BRST and antiBRST transformations, realized in terms of superspace translations. The Ward identities related to the generalized gauge-fixing procedure are obtained.

  19. An extension of the generalized nonlocal theory for the mode analysis of plasmonic waveguides at telecommunication frequency

    Science.gov (United States)

    Teng, Da; Cao, Qing; Wang, Kai

    2017-05-01

    We present an extension of the generalized nonlocal (GNL) optical response theory for the mode analysis of several plasmonic waveguides. We show that, compared with the local description, the imaginary part of the effective mode index is enlarged using the GNL response model. We ascribe this enlargement to the ‘effective’ surface modification and the induced charge diffusion. This result is quite different from that of the hydrodynamic model, where the imaginary part becomes smaller compared with that of the local model. Further, we investigate the influence of geometry parameters on propagation properties and find that the nonlocal effects are much more remarkable for smaller gap and sharper tip. Although the introduction of diffusion has a negative impact on the propagation length, it reveals the true physical insight and should be taken care when dealing with nanoplasmonic waveguide for photonic integration applications.

  20. Generalized Maximum Entropy

    Science.gov (United States)

    Cheeseman, Peter; Stutz, John

    2005-01-01

    A long standing mystery in using Maximum Entropy (MaxEnt) is how to deal with constraints whose values are uncertain. This situation arises when constraint values are estimated from data, because of finite sample sizes. One approach to this problem, advocated by E.T. Jaynes [1], is to ignore this uncertainty, and treat the empirically observed values as exact. We refer to this as the classic MaxEnt approach. Classic MaxEnt gives point probabilities (subject to the given constraints), rather than probability densities. We develop an alternative approach that assumes that the uncertain constraint values are represented by a probability density {e.g: a Gaussian), and this uncertainty yields a MaxEnt posterior probability density. That is, the classic MaxEnt point probabilities are regarded as a multidimensional function of the given constraint values, and uncertainty on these values is transmitted through the MaxEnt function to give uncertainty over the MaXEnt probabilities. We illustrate this approach by explicitly calculating the generalized MaxEnt density for a simple but common case, then show how this can be extended numerically to the general case. This paper expands the generalized MaxEnt concept introduced in a previous paper [3].

  1. Beyond generalized Proca theories

    Directory of Open Access Journals (Sweden)

    Lavinia Heisenberg

    2016-09-01

    Full Text Available We consider higher-order derivative interactions beyond second-order generalized Proca theories that propagate only the three desired polarizations of a massive vector field besides the two tensor polarizations from gravity. These new interactions follow the similar construction criteria to those arising in the extension of scalar–tensor Horndeski theories to Gleyzes–Langlois–Piazza–Vernizzi (GLPV theories. On the isotropic cosmological background, we show the existence of a constraint with a vanishing Hamiltonian that removes the would-be Ostrogradski ghost. We study the behavior of linear perturbations on top of the isotropic cosmological background in the presence of a matter perfect fluid and find the same number of propagating degrees of freedom as in generalized Proca theories (two tensor polarizations, two transverse vector modes, and two scalar modes. Moreover, we obtain the conditions for the avoidance of ghosts and Laplacian instabilities of tensor, vector, and scalar perturbations. We observe key differences in the scalar sound speed, which is mixed with the matter sound speed outside the domain of generalized Proca theories.

  2. Beyond generalized Proca theories

    Science.gov (United States)

    Heisenberg, Lavinia; Kase, Ryotaro; Tsujikawa, Shinji

    2016-09-01

    We consider higher-order derivative interactions beyond second-order generalized Proca theories that propagate only the three desired polarizations of a massive vector field besides the two tensor polarizations from gravity. These new interactions follow the similar construction criteria to those arising in the extension of scalar-tensor Horndeski theories to Gleyzes-Langlois-Piazza-Vernizzi (GLPV) theories. On the isotropic cosmological background, we show the existence of a constraint with a vanishing Hamiltonian that removes the would-be Ostrogradski ghost. We study the behavior of linear perturbations on top of the isotropic cosmological background in the presence of a matter perfect fluid and find the same number of propagating degrees of freedom as in generalized Proca theories (two tensor polarizations, two transverse vector modes, and two scalar modes). Moreover, we obtain the conditions for the avoidance of ghosts and Laplacian instabilities of tensor, vector, and scalar perturbations. We observe key differences in the scalar sound speed, which is mixed with the matter sound speed outside the domain of generalized Proca theories.

  3. 41 CFR 102-37.70 - How should a transferee account for the receipt of a larger or smaller number of items than...

    Science.gov (United States)

    2010-07-01

    ... PROPERTY General Provisions Donation Overview § 102-37.70 How should a transferee account for the receipt... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How should a transferee....70 Section 102-37.70 Public Contracts and Property Management Federal Property Management...

  4. In vivo microvascular mosaics show air embolism reduction after perfluorocarbon emulsion treatment.

    Science.gov (United States)

    Torres Filho, Ivo P; Torres, Luciana N; Spiess, Bruce D

    2012-11-01

    Massive arteriolar gas embolism (AGE) has never been evaluated in vivo using intravital microscopy and previous perfluorocarbon (PFC) emulsions were only effective in AGE when administered before AGE. We implemented a new system for quantitative studies of massive AGE using brightfield microscopy and tested a treatment with a third-generation PFC emulsion after massive AGE. We studied bubble dynamics in cremaster muscles from anesthetized rats after AGE was induced by direct air injection into the femoral artery ipsilateral to the studied muscle. Using a motorized microscope stage and a color camera, in vivo microvascular mosaics were produced on-line from over 2000 digital images to evaluate multiple networks in order to investigate the distribution, lodging, breaking, reduction and moving of 105 air bubbles in microvessels. Thirty minutes after PFC treatment, there was a reduction of 80% in bubble volume while untreated and saline-treated rats showed significantly smaller decreases of 33% and 40%, respectively (pbubbles also dissolved into a larger number of smaller bubbles after PFC treatment. The proposed methodology may prove useful for rapid in vivo data acquisition from large networks. Since large air bubbles broke-up, decreased in length and volume, and moved toward smaller microvessels, the study provides quantitative data to support a mechanism by which PFC may improve tissue blood flow following massive AGE. The findings suggest that this new generation of PFC emulsions administered after severe AGE may reach compromised microvascular networks and provide help to alleviate microvascular obstruction by increasing air bubble reabsorption.

  5. Protein Thermostability Is Owing to Their Preferences to Non-Polar Smaller Volume Amino Acids, Variations in Residual Physico-Chemical Properties and More Salt-Bridges.

    Directory of Open Access Journals (Sweden)

    Anindya Sundar Panja

    Full Text Available Protein thermostability is an important field for its evolutionary perspective of mesophilic versus thermophilic relationship and for its industrial/ therapeutic applications.Presently, a total 400 (200 thermophilic and 200 mesophilic homologue proteins were studied utilizing several software/databases to evaluate their amino acid preferences. Randomly selected 50 homologous proteins with available PDB-structure of each group were explored for the understanding of the protein charges, isoelectric-points, hydrophilicity, hydrophobicity, tyrosine phosphorylation and salt-bridge occurrences. These 100 proteins were further probed to generate Ramachandran plot/data for the gross secondary structure prediction in and comparison between the thermophilic and mesophilic proteins.Present results strongly suggest that nonpolar smaller volume amino acids Ala (χ2 = 238.54, p<0.001 and Gly (χ2 = 73.35, p<0.001 are highly and Val moderately (χ2 = 144.43, p<0.001 occurring in the 85% of thermophilic proteins. Phospho-regulated Tyr and redox-sensitive Cys are also moderately distributed (χ2~20.0, p<0.01 in a larger number of thermophilic proteins. A consistent lower distribution of thermophilicity and discretely higher distribution of hydrophobicity is noticed in a large number of thermophilic versus their mesophilic protein homolog. The mean differences of isoelectric points and charges are found to be significantly less (7.11 vs. 6.39, p<0.05 and 1 vs. -0.6, p<0.01, respectively in thermophilic proteins compared to their mesophilic counterpart. The possible sites for Tyr phosphorylation are noticed to be 25% higher (p<0.05 in thermophilic proteins. The 60% thermophiles are found with higher number of salt bridges in this study. The average percentage of salt-bridge of thermophiles is found to be higher by 20% than their mesophilic homologue. The GLU-HIS and GLU-LYS salt-bridge dyads are calculated to be significantly higher (p<0.05 and p<0

  6. Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volume.

    Directory of Open Access Journals (Sweden)

    Sophie J Bernelot Moens

    Full Text Available Exotosin (EXT proteins are involved in the chain elongation step of heparan sulfate (HS biosynthesis, which is intricately involved in organ development. Loss of function mutations (LOF in EXT1 and EXT2 result in hereditary exostoses (HME. Interestingly, HS plays a role in pancreas development and beta-cell function, and genetic variations in EXT2 are associated with an increased risk for type 2 diabetes mellitus. We hypothesized that loss of function of EXT1 or EXT2 in subjects with hereditary multiple exostoses (HME affects pancreatic insulin secretion capacity and development. We performed an oral glucose tolerance test (OGTT followed by hyperglycemic clamps to investigate first-phase glucose-stimulated insulin secretion (GSIS in HME patients and age and gender matched non-affected relatives. Pancreas volume was assessed with magnetic resonance imaging (MRI. OGTT did not reveal significant differences in glucose disposal, but there was a markedly lower GSIS in HME subjects during hyperglycemic clamp (iAUC HME: 0.72 [0.46-1.16] vs. controls 1.53 [0.69-3.36] nmol·l-1·min-1, p<0.05. Maximal insulin response following arginine challenge was also significantly attenuated (iAUC HME: 7.14 [4.22-10.5] vs. controls 10.2 [7.91-12.70] nmol·l-1·min-1 p<0.05, indicative of an impaired beta-cell reserve. MRI revealed a significantly smaller pancreatic volume in HME subjects (HME: 72.0±15.8 vs. controls 96.5±26.0 cm3 p = 0.04. In conclusion, loss of function of EXT proteins may affect beta-cell mass and insulin secretion capacity in humans, and render subjects at a higher risk of developing type 2 diabetes when exposed to environmental risk factors.

  7. Effect of solvent permittivity on the thermodynamic behavior of HCl solutions: analysis using the smaller-ion shell model of strong electrolytes.

    Science.gov (United States)

    Fraenkel, Dan

    2011-12-15

    The recently introduced smaller-ion shell (SiS) treatment of strong binary electrolyte solutions [Fraenkel, D. Mol. Phys. 2010, 108, 1435] that extends the Debye-Hückel theory to size-dissimilar ions is very effective for many electrolytes of various families up to moderate ionic concentration. The (molal) mean ionic activity coefficient, γ(±), as a function of the reciprocal screening length, κ, hence ionic strength, I, is given by an analytic mathematical expression that incorporates the three ion-size parameters (ISPs). Experimental γ(±) data are fitted with calculated values derived from ISPs that seem to adequately represent the relevant mean effective ionic sizes. The SiS analysis has been lately shown effective for aqueous HCl, HBr, HI, and HClO(4) at 25 °C, at which the solvent permittivity, ε, is 78.4 [Fraenkel, D. J. Phys. Chem. B 2011, 115, 557]. In this paper, the behavior of HCl in solvents ranging in ε between approximately 10 and 80 is analyzed and discussed. The SiS treatment is found again suitable for computing γ(±) values that agree with experiment. Within the concentration range of the available experimental data, ion pairing is not indicated and, contrary to literature claims, HCl appears fully ionized even at 0.5 m (molal) with ε ion ISPs increase linearly with 1/ε. The chemical nature of the solution has no observable effect on γ(±) and on ISPs. The present analysis supports the view that electrolyte theories in which the solvent is considered at the McMillan-Mayer level can be successful and valuable.

  8. Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction

    Science.gov (United States)

    Elmonem, Mohamed A.; Khalil, Ramzi; Khodaparast, Ladan; Khodaparast, Laleh; Arcolino, Fanny O.; Morgan, Joseph; Pastore, Anna; Tylzanowski, Przemko; Ny, Annelii; Lowe, Martin; de Witte, Peter A.; Baelde, Hans J.; van den Heuvel, Lambertus P.; Levtchenko, Elena

    2017-01-01

    The human ubiquitous protein cystinosin is responsible for transporting the disulphide amino acid cystine from the lysosomal compartment into the cytosol. In humans, Pathogenic mutations of CTNS lead to defective cystinosin function, intralysosomal cystine accumulation and the development of cystinosis. Kidneys are initially affected with generalized proximal tubular dysfunction (renal Fanconi syndrome), then the disease rapidly affects glomeruli and progresses towards end stage renal failure and multiple organ dysfunction. Animal models of cystinosis are limited, with only a Ctns knockout mouse reported, showing cystine accumulation and late signs of tubular dysfunction but lacking the glomerular phenotype. We established and characterized a mutant zebrafish model with a homozygous nonsense mutation (c.706 C > T; p.Q236X) in exon 8 of ctns. Cystinotic mutant larvae showed cystine accumulation, delayed development, and signs of pronephric glomerular and tubular dysfunction mimicking the early phenotype of human cystinotic patients. Furthermore, cystinotic larvae showed a significantly increased rate of apoptosis that could be ameliorated with cysteamine, the human cystine depleting therapy. Our data demonstrate that, ctns gene is essential for zebrafish pronephric podocyte and proximal tubular function and that the ctns-mutant can be used for studying the disease pathogenic mechanisms and for testing novel therapies for cystinosis. PMID:28198397

  9. Cosmology in beyond-generalized Proca theories

    Science.gov (United States)

    Nakamura, Shintaro; Kase, Ryotaro; Tsujikawa, Shinji

    2017-05-01

    The beyond-generalized Proca theories are the extension of second-order massive vector-tensor theories (dubbed generalized Proca theories) with two transverse vector modes and one longitudinal scalar besides two tensor polarizations. Even with this extension, the propagating degrees of freedom remain unchanged on the isotropic cosmological background without an Ostrogradski instability. We study the cosmology in beyond-generalized Proca theories by paying particular attention to the dynamics of late-time cosmic acceleration and resulting observational consequences. We derive conditions for avoiding ghosts and instabilities of tensor, vector, and scalar perturbations and discuss viable parameter spaces in concrete models allowing the dark energy equation of state smaller than -1 . The propagation speeds of those perturbations are subject to modifications beyond the domain of generalized Proca theories. There is a mixing between scalar and matter sound speeds, but such a mixing is suppressed during most of the cosmic expansion history without causing a new instability. On the other hand, we find that derivative interactions arising in beyond-generalized Proca theories give rise to important modifications to the cosmic growth history. The growth rate of matter perturbations can be compatible with the redshift-space distortion data due to the realization of gravitational interaction weaker than that in generalized Proca theories. Thus, it is possible to distinguish the dark energy model in beyond-generalized Proca theories from the counterpart in generalized Proca theories as well as from the Λ CDM model.

  10. Impact Factors Show Increased Use of AGU Journals in 2008

    Science.gov (United States)

    Ford, Barbara Meyers

    2009-07-01

    The latest numbers released from Journal Citation Reports (JCR), published annually by Thomson Reuters, show large increases in the impact factor (IF) for several AGU journals. IFs are one way for publishers to know that readers have found their journals useful and of value in research. A journal's IF is calculated by taking the total number of citations to articles published by a given journal in the past 2 years and dividing it by the total number of papers published by the journal in the same time period. More generally, it can be seen as the frequency with which articles in a journal have been cited over the past year. The numbers speak for themselves (see Table 1).

  11. General Nuclear Medicine

    Science.gov (United States)

    ... Physician Resources Professions Site Index A-Z General Nuclear Medicine Nuclear medicine imaging uses small amounts of ... limitations of General Nuclear Medicine? What is General Nuclear Medicine? Nuclear medicine is a branch of medical ...

  12. General Ultrasound Imaging

    Science.gov (United States)

    ... Physician Resources Professions Site Index A-Z General Ultrasound Ultrasound imaging uses sound waves to produce pictures ... limitations of General Ultrasound Imaging? What is General Ultrasound Imaging? Ultrasound is safe and painless, and produces ...

  13. Calfornia General Plans Rural

    Data.gov (United States)

    California Department of Resources — We undertook creating the first ever seamless statewide General Plan map for California. All county general plans and many city general plans were integrated into 1...

  14. Calfornia General Plans

    Data.gov (United States)

    California Department of Resources — We undertook creating the first ever seamless statewide General Plan map for California. All county general plans and many city general plans were integrated into 1...

  15. Calfornia General Plans

    Data.gov (United States)

    California Department of Resources — We undertook creating the first ever seamless statewide General Plan map for California. All county general plans and many city general plans were integrated into 1...

  16. Tomato Fruits Show Wide Phenomic Diversity but Fruit Developmental Genes Show Low Genomic Diversity.

    Science.gov (United States)

    Mohan, Vijee; Gupta, Soni; Thomas, Sherinmol; Mickey, Hanjabam; Charakana, Chaitanya; Chauhan, Vineeta Singh; Sharma, Kapil; Kumar, Rakesh; Tyagi, Kamal; Sarma, Supriya; Gupta, Suresh Kumar; Kilambi, Himabindu Vasuki; Nongmaithem, Sapana; Kumari, Alka; Gupta, Prateek; Sreelakshmi, Yellamaraju; Sharma, Rameshwar

    2016-01-01

    Domestication of tomato has resulted in large diversity in fruit phenotypes. An intensive phenotyping of 127 tomato accessions from 20 countries revealed extensive morphological diversity in fruit traits. The diversity in fruit traits clustered the accessions into nine classes and identified certain promising lines having desirable traits pertaining to total soluble salts (TSS), carotenoids, ripening index, weight and shape. Factor analysis of the morphometric data from Tomato Analyzer showed that the fruit shape is a complex trait shared by several factors. The 100% variance between round and flat fruit shapes was explained by one discriminant function having a canonical correlation of 0.874 by stepwise discriminant analysis. A set of 10 genes (ACS2, COP1, CYC-B, RIN, MSH2, NAC-NOR, PHOT1, PHYA, PHYB and PSY1) involved in various plant developmental processes were screened for SNP polymorphism by EcoTILLING. The genetic diversity in these genes revealed a total of 36 non-synonymous and 18 synonymous changes leading to the identification of 28 haplotypes. The average frequency of polymorphism across the genes was 0.038/Kb. Significant negative Tajima'D statistic in two of the genes, ACS2 and PHOT1 indicated the presence of rare alleles in low frequency. Our study indicates that while there is low polymorphic diversity in the genes regulating plant development, the population shows wider phenotype diversity. Nonetheless, morphological and genetic diversity of the present collection can be further exploited as potential resources in future.

  17. Spontaneously induced general relativity with holographic interior and general exterior

    CERN Document Server

    Shen, Xiao-Qing; Yang, Guo-Hong

    2012-01-01

    The general relativity (GR) might be viewed as a spontaneously induced theory from the scalar-tensor gravity, in which the would-have-been horizon connects the exterior solution of GR with a novel core of vanishing spatial volume. Using a simple but robust analytic method, we give the nontrivial core metric for the general exterior. Then we show that all the nontrivial features of the core, including the locally holographic entropy packing, are not influenced by the general exterior. We also investigate whether other modified theories of gravity can permit the nontrivial core.

  18. GENERALIZED DERIVATIONS ON PARABOLIC SUBALGEBRAS OF GENERAL LINEAR LIE ALGEBRAS

    Institute of Scientific and Technical Information of China (English)

    陈正新

    2014-01-01

    Let P be a parabolic subalgebra of a general linear Lie algebra gl(n, F) over a field F, where n ≥ 3, F contains at least n different elements, and char(F) 6= 2. In this article, we prove that generalized derivations, quasiderivations, and product zero derivations of P coincide, and any generalized derivation of P is a sum of an inner derivation, a central quasiderivation, and a scalar multiplication map of P. We also show that any commuting automorphism of P is a central automorphism, and any commuting derivation of P is a central derivation.

  19. The Geometric Nonlinear Generalized Brazier Effect

    DEFF Research Database (Denmark)

    Nikolajsen, Jan Ánike; Lauridsen, Peter Riddersholm; Damkilde, Lars

    2016-01-01

    denoted the generalized Brazier effect. The original work of Brazier dealt with very large deformations that changed the cross section significantly and hereby also the bending moment of inertia and the bending moment capacity. In this paper the aim is to describe the Brazier effect for smaller...... that the generalized Brazier effect is a local effect not influencing the overall mechanical behavior of the structure significantly. The offset is a nonlinear geometric beam-type Finite Element calculation, which takes into account the large displacements and rotations. The beam-type model defines the stresses which...... deformation not taking into account the change in moment of inertia. However, the generalized Brazier effect gives additional stresses directed perpendicular to the beam axis. In composite structures these extra stresses may influence the fatigue life significantly. The paper demonstrates a linearized method...

  20. Kaluza's theory in generalized coordinates

    CERN Document Server

    García-Perciante, A L; García-Colin, L S; Garcia-Perciante, Ana Laura; Sandoval-Villalbazo, Alfredo

    2001-01-01

    Maxwell's equations can be obtained in generalized coordinates by considering the electromagnetic field as an external agent. The work here presented shows how to obtain the electrodynamics for a charged particle in generalized coordinates eliminating the concept of external force. Based on Kaluza's formalism, the one here presented extends the 5x5 metric into a 6x6 space-time giving enough room to include magnetic monopoles in a very natural way.

  1. Mixtures of thermostable enzymes show high performance in biomass saccharification.

    Science.gov (United States)

    Kallioinen, Anne; Puranen, Terhi; Siika-aho, Matti

    2014-07-01

    Optimal enzyme mixtures of six Trichoderma reesei enzymes and five thermostable enzyme components were developed for the hydrolysis of hydrothermally pretreated wheat straw, alkaline oxidised sugar cane bagasse and steam-exploded bagasse by statistically designed experiments. Preliminary studies to narrow down the optimization parameters showed that a cellobiohydrolase/endoglucanase (CBH/EG) ratio of 4:1 or higher of thermostable enzymes gave the maximal CBH-EG synergy in the hydrolysis of hydrothermally pretreated wheat straw. The composition of optimal enzyme mixtures depended clearly on the substrate and on the enzyme system studied. The optimal enzyme mixture of thermostable enzymes was dominated by Cel7A and required a relatively high amount of xylanase, whereas with T. reesei enzymes, the high proportion of Cel7B appeared to provide the required xylanase activity. The main effect of the pretreatment method was that the required proportion of xylanase was higher and the proportion of Cel7A lower in the optimized mixture for hydrolysis of alkaline oxidised bagasse than steam-exploded bagasse. In prolonged hydrolyses, less Cel7A was generally required in the optimal mixture. Five-component mixtures of thermostable enzymes showed comparable hydrolysis yields to those of commercial enzyme mixtures.

  2. Dogs show left facial lateralization upon reunion with their owners.

    Science.gov (United States)

    Nagasawa, Miho; Kawai, Emi; Mogi, Kazutaka; Kikusui, Takefumi

    2013-09-01

    Domestic dogs demonstrate behavioral laterality in response to emotional stimuli; those responses include tail wagging and head turning. The dog is the species with the closest relationship to humans; dogs can express strong social emotions (e.g., attachment and separation anxiety) to specific persons, such as their owners. In this study, we examined whether dogs demonstrate more facial laterality when reunited with their owners than when they encounter an unfamiliar person in an unfamiliar situation. We also examined whether the observed laterality was specific to positive social stimuli (i.e., the owner) or a general response to nonsocial positive stimuli (i.e., toys). The dogs' facial expressions were recorded by a high-speed video camera during the presentation of emotional stimuli and the acceleration rates of parts of their faces were analyzed. The results showed that the left eyebrow moved more when the owner was present than at baseline. No bias in terms of eyebrow movement was observed when the dogs saw attractive toys. These results suggest that dogs show facial laterality in response to emotional stimuli. This laterality was specific to social stimuli, probably reflecting the dog's attachment to the owner.

  3. Categorical Generalization and Physical Structuralism

    CERN Document Server

    Lal, Raymond

    2014-01-01

    Category theory has become central to certain aspects of theoretical physics. Bain [Synthese, 190:1621--1635 (2013)] has recently argued that this has significance for ontic structural realism. We argue against this claim. In so doing, we uncover two pervasive forms of category-theoretic generalization. We call these `generalization by duality' and `generalization by categorifying physical processes'. We describe in detail how these arise, and explain their significance using detailed examples. We show that their significance is two-fold: the articulation of high-level physical concepts, and the generation of new models.

  4. GENERALIZED WEAK FUNCTIONS

    Institute of Scientific and Technical Information of China (English)

    丁夏畦; 罗佩珠

    2004-01-01

    In this paper the authors introduce some new ideas on generalized numbers and generalized weak functions. They prove that the product of any two weak functions is a generalized weak function. So in particular they solve the problem of the multiplication of two generalized functions.

  5. Generalized holomorphic structures

    Science.gov (United States)

    Wang, Yicao

    2014-12-01

    We define the notion of generalized holomorphic principal bundles and establish that their associated vector bundles of holomorphic representations are generalized holomorphic vector bundles defined by M. Gualtieri. Motivated by our definition, several examples of generalized holomorphic structures are constructed. A reduction theorem of generalized holomorphic structures is also included.

  6. How general is general information construct?

    Directory of Open Access Journals (Sweden)

    Predrag Zarevski

    2005-04-01

    Full Text Available There is a small number of constructs in the field of differential psychology that have raised so much debate between psychologists and professionals in related disciplines as is the case of general (verbal information construct. It seemed reasonable to test the validity of this construct measured with general information test in comparison with other measures of knowledge (cultural knowledge, vocabulary, knowledge of the most recent events, foreign language knowledge, and a standard verbal type g test. A sample of 376 candidates for state services was tested in a selection situation. Three analyses were conducted to determine the position of general information test in the space of other verbal competency measures. The first analysis questioned latent structure of the space of four tests having the same format and asking about the knowledge of international terms, general culture, knowledge of most recent events, and general information. The second analysis included the g-factor intelligence test so to see how the above described structure changes when this new test is introduced. The third analysis introduced an English language test. In all of the three component analyses only one eigenvalue was larger than 1 and it explained between 52 and 64% of variance. In all analyses general information test had the highest projection on the only significant latent dimension of these cognitive spaces. In other words, it can be concluded that the construct of general information is in the center of this hyperconus. That is why we consider measurement of general information knowledge, as well as the construct itself, to be an important question in psychological diagnostics. Thus, it is important to go further with the investigation of this construct because it does not seem that it is named general information by accident.

  7. Mining Frequent Generalized Itemsets and Generalized Association Rules Without Redundancy

    Institute of Scientific and Technical Information of China (English)

    Daniel Kunkle; Donghui Zhang; Gene Cooperman

    2008-01-01

    This paper presents some new algorithms to efficiently mine max frequent generalized itemsets (g-itemsets) and essential generalized association rules (g-rules). These are compact and general representations for all frequent patterns and all strong association rules in the generalized environment. Our results fill an important gap among algorithms for frequent patterns and association rules by combining two concepts. First, generalized itemsets employ a taxonomy of items, rather than a fiat list of items. This produces more natural frequent itemsets and associations such as (meat, milk) instead of (beef, milk), (chicken, milk), etc. Second, compact representations of frequent itemsets and strong rules, whose result size is exponentially smaller, can solve a standard dilemma in mining patterns: with small threshold values for support and confidence, the user is overwhelmed by the extraordinary number of identified patterns and associations; but with large threshold values, some interesting patterns and associations fail to be identified. Our algorithms can also expand those max frequent g-itemsets and essential g-rules into the much larger set of ordinary frequent g-itemsets and strong g-rules. While that expansion is not recommended in most practical cases, we do so in order to present a comparison with existing algorithms that only handle ordinary frequent g-itemsets. In this case, the new algorithm is shown to be thousands, and in some cases millions, of the time faster than previous algorithms. Further, the new algorithm succeeds in analyzing deeper taxonomies, with the depths of seven or more. Experimental results for previous algorithms limited themselves to taxonomies with depth at most three or four. In each of the two problems, a straightforward lattice-based approach is briefly discussed and then a classificationbased algorithm is developed. In particular, the two classification-based algorithms are MFGI_class for mining max frequent g-itemsets and EGR

  8. Introduction to general and generalized linear models

    CERN Document Server

    Madsen, Henrik

    2010-01-01

    IntroductionExamples of types of data Motivating examples A first view on the modelsThe Likelihood PrincipleIntroduction Point estimation theory The likelihood function The score function The information matrix Alternative parameterizations of the likelihood The maximum likelihood estimate (MLE) Distribution of the ML estimator Generalized loss-function and deviance Quadratic approximation of the log-likelihood Likelihood ratio tests Successive testing in hypothesis chains Dealing with nuisance parameters General Linear ModelsIntroduction The multivariate normal distribution General linear mod

  9. OLEDS FOR GENERAL LIGHTING

    Energy Technology Data Exchange (ETDEWEB)

    Anil Duggal; Don Foust; Chris Heller; Bill Nealon; Larry Turner; Joe Shiang; Nick Baynes; Tim Butler; Nalin Patel

    2004-02-29

    The goal of this program was to reduce the long term technical risks that were keeping the lighting industry from embracing and developing organic light-emitting diode (OLED) technology for general illumination. The specific goal was to develop OLEDs for lighting to the point where it was possible to demonstrate a large area white light panel with brightness and light quality comparable to a fluorescence source and with an efficacy comparable to that of an incandescent source. it was recognized that achieving this would require significant advances in three area: (1) the improvement of white light quality for illumination, (2) the improvement of OLED energy efficiency at high brightness, and (3) the development of cost-effective large area fabrication techniques. The program was organized such that, each year, a ''deliverable'' device would be fabricated which demonstrated progress in one or more of the three critical research areas. In the first year (2001), effort concentrated on developing an OLED capable of generating high illumination-quality white light. Ultimately, a down-conversion method where a blue OLED was coupled with various down-conversion layers was chosen. Various color and scattering models were developed to aid in material development and device optimization. The first year utilized this approach to deliver a 1 inch x 1 inch OLED with higher illumination-quality than available fluorescent sources. A picture of this device is shown and performance metrics are listed. To their knowledge, this was the first demonstration of true illumination-quality light from an OLED. During the second year, effort concentrated on developing a scalable approach to large area devices. A novel device architecture consisting of dividing the device area into smaller elements that are monolithically connected in series was developed. In the course of this development, it was realized that, in addition to being scalable, this approach made the device

  10. Can recurrence networks show small-world property?

    Energy Technology Data Exchange (ETDEWEB)

    Jacob, Rinku, E-mail: rinku.jacob.vallanat@gmail.com [Department of Physics, The Cochin College, Cochin, 682002 (India); Harikrishnan, K.P., E-mail: kp_hk2002@yahoo.co.in [Department of Physics, The Cochin College, Cochin, 682002 (India); Misra, R., E-mail: rmisra@iucaa.in [Inter University Centre for Astronomy and Astrophysics, Pune, 411007 (India); Ambika, G., E-mail: g.ambika@iiserpune.ac.in [Indian Institute of Science Education and Research, Pune, 411008 (India)

    2016-08-12

    Recurrence networks are complex networks, constructed from time series data, having several practical applications. Though their properties when constructed with the threshold value ϵ chosen at or just above the percolation threshold of the network are quite well understood, what happens as the threshold increases beyond the usual operational window is still not clear from a complex network perspective. The present Letter is focused mainly on the network properties at intermediate-to-large values of the recurrence threshold, for which no systematic study has been performed so far. We argue, with numerical support, that recurrence networks constructed from chaotic attractors with ϵ equal to the usual recurrence threshold or slightly above cannot, in general, show small-world property. However, if the threshold is further increased, the recurrence network topology initially changes to a small-world structure and finally to that of a classical random graph as the threshold approaches the size of the strange attractor. - Highlights: • Properties of recurrence networks at intermediate-to-large values of recurrence threshold are analyzed from a complex network perspective. • Using a combined plot of characteristic path length and clustering coefficient, it is shown that the recurrence network constructed with recurrence threshold equal to or just above the percolation threshold cannot, in general, display small-world property. • As the recurrence threshold is increased from its usual operational window, the resulting network makes a smooth transition initially to a small-world network for an intermediate range of thresholds and finally to the classical random graph as the threshold becomes comparable to the size of the attractor.

  11. Invariants and flavour in the general Two Higgs Doublet Model

    Energy Technology Data Exchange (ETDEWEB)

    Botella, F.J., E-mail: fbotella@uv.es [Departament de Física Teòrica and IFIC, Universitat de València-CSIC, E-46100, Burjassot (Spain); Branco, G.C., E-mail: gustavo.branco@cern.ch [Departamento de Física and Centro de Física Teórica de Partículas (CFTP), Instituto Superior Técnico, Av. Rovisco Pais, P-1049-001 Lisboa (Portugal); Rebelo, M.N., E-mail: margarida.rebelo@cern.ch [Universidade Técnica de Lisboa, Centro de Física Teórica de Partículas (CFTP), Instituto Superior Técnico, Av. Rovisco Pais, P-1049-001 Lisboa (Portugal)

    2013-05-13

    The flavour structure of the general Two Higgs Doublet Model (2HDM) is analysed and a detailed study of the parameter space is presented, showing that flavour mixing in the 2HDM can be parametrized by various unitary matrices which arise from the misalignment in flavour space between pairs of various Hermitian flavour matrices which can be constructed within the model. This is entirely analogous to the generation of the CKM matrix in the Standard Model (SM). We construct weak basis invariants which can give insight into the physical implications of any flavour model, written in an arbitrary weak basis (WB) in the context of 2HDM. We apply this technique to two special cases, models with MFV and models with NNI structures. In both cases non-trivial CP-odd WB invariants arise in a mass power order much smaller than what one encounters in the SM, which can have important implications for baryogenesis in the framework of the general 2HDM.

  12. Generalized Nonlinear Yule Models

    Science.gov (United States)

    Lansky, Petr; Polito, Federico; Sacerdote, Laura

    2016-10-01

    With the aim of considering models related to random graphs growth exhibiting persistent memory, we propose a fractional nonlinear modification of the classical Yule model often studied in the context of macroevolution. Here the model is analyzed and interpreted in the framework of the development of networks such as the World Wide Web. Nonlinearity is introduced by replacing the linear birth process governing the growth of the in-links of each specific webpage with a fractional nonlinear birth process with completely general birth rates. Among the main results we derive the explicit distribution of the number of in-links of a webpage chosen uniformly at random recognizing the contribution to the asymptotics and the finite time correction. The mean value of the latter distribution is also calculated explicitly in the most general case. Furthermore, in order to show the usefulness of our results, we particularize them in the case of specific birth rates giving rise to a saturating behaviour, a property that is often observed in nature. The further specialization to the non-fractional case allows us to extend the Yule model accounting for a nonlinear growth.

  13. General Composite Higgs Models

    CERN Document Server

    Marzocca, David; Shu, Jing

    2012-01-01

    We construct a general class of pseudo-Goldstone composite Higgs models, within the minimal $SO(5)/SO(4)$ coset structure, that are not necessarily of moose-type. We characterize the main properties these models should have in order to give rise to a Higgs mass at around 125 GeV. We assume the existence of relatively light and weakly coupled spin 1 and 1/2 resonances. In absence of a symmetry principle, we introduce the Minimal Higgs Potential (MHP) hypothesis: the Higgs potential is assumed to be one-loop dominated by the SM fields and the above resonances, with a contribution that is made calculable by imposing suitable generalizations of the first and second Weinberg sum rules. We show that a 125 GeV Higgs requires light, often sub-TeV, fermion resonances. Their presence can also be important for the model to successfully pass the electroweak precision tests. Interestingly enough, the latter can be passed also by models with a heavy Higgs around 320 GeV. The composite Higgs models of the moose-type conside...

  14. Generalized Nonlinear Yule Models

    Science.gov (United States)

    Lansky, Petr; Polito, Federico; Sacerdote, Laura

    2016-11-01

    With the aim of considering models related to random graphs growth exhibiting persistent memory, we propose a fractional nonlinear modification of the classical Yule model often studied in the context of macroevolution. Here the model is analyzed and interpreted in the framework of the development of networks such as the World Wide Web. Nonlinearity is introduced by replacing the linear birth process governing the growth of the in-links of each specific webpage with a fractional nonlinear birth process with completely general birth rates. Among the main results we derive the explicit distribution of the number of in-links of a webpage chosen uniformly at random recognizing the contribution to the asymptotics and the finite time correction. The mean value of the latter distribution is also calculated explicitly in the most general case. Furthermore, in order to show the usefulness of our results, we particularize them in the case of specific birth rates giving rise to a saturating behaviour, a property that is often observed in nature. The further specialization to the non-fractional case allows us to extend the Yule model accounting for a nonlinear growth.

  15. Generalized Ideal Gas Equations for Structureful Universe

    Directory of Open Access Journals (Sweden)

    Khalid Khan

    2006-09-01

    Full Text Available We have derived generalized ideal gas equations for a structureful universe consistingof all forms of matters. We have assumed a universe that contains superclusters. Superclusters arethen made of clusters. Each cluster can be further divided into smaller ones and so on. We havederived an expression for the entropy of such a universe. Our model is rather independent of thegeometry of the intermediate clusters. Our calculations are valid for a non-interacting universewithin non-relativistic limits. We suggest that structure formation can reduce the expansion rateof the universe.

  16. Schumpeter's general theory of social evolution

    DEFF Research Database (Denmark)

    Andersen, Esben Sloth

    The recent neo-Schumpeterian and evolutionary economics appears to cover a much smaller range of topics than Joseph Schumpeter confronted. Thus, it has hardly been recognised that Schumpeter wanted to develop a general theory that served the analysis of evolution in any sector of social life...... as well as the analysis of the evolution of social life as a whole. This paper demonstrates this ambition by studying his first two books (from 1908 and 1912, partly available in recent English translations). Schumpeter's starting point was the Walrasian System, which he generalised for the study of any...

  17. Introduction to general relativity

    CERN Document Server

    Parthasarthy, R

    2016-01-01

    INTRODUCTION TO GENERAL RELATIVITY begins with a description of the geometry of curved space, explaining geodesics, parallel transport, covariant differentiation, geodesic deviation and spacetime symmetry by killing vectors. It then introduces Einstein's theory of gravitation followed by Schwarzschild solution with its relevance to Positive Mass theorem. The three tests for Einstein's gravity are explained. Other exact solutions such as Vaidya, Kerr and Reisner - Nordstrom metric are included. In the Chapter on cosmological solutions, a detailed description of Godel metric is provided. It then introduces five dimensional spacetime of Kaluza showing the unification of gravity with electromagnetism. This is extended to include non-Abelian gauge theory by invoking compact extra dimensions. Explicit expressions in this case for Christoffel connections and ricci tensor are derived and the higher dimensional gravity action is shown to compactification are given.

  18. Nanotechnologies a general introduction

    CERN Document Server

    CERN. Geneva; Ferrari, M; Li Bassi, A

    2007-01-01

    After a brief description of what is nanotechnology (a triple definition will be attempted) and of its importance for the society, this first lecture manly aims at showing how nanoscience makes various nanotechnologies possible. The surprising story of direct imaging and manipulation of atoms (scanning probe microscopies will be the specific subject of the third lecture by prof. Andrea Li Bassi) is told to naturally introduce the crucial role of quantum confinement and surface defects. The electronic and vibrational properties of nanostructures are then discussed to understand the connection between the deeply modified (with respect to the bulk) quantum spectra and the physico-chemical properties of nanoscopic objects. In this context the concept of superatom (and its generalizations) is stressed. The essential role of both size and size control is finally emphasized discussing some significant applications in the fields of materials, devices and medicine. To this last argument (nanomedicine) the second lectu...

  19. GENERALIZED DOUBLE PARETO SHRINKAGE.

    Science.gov (United States)

    Armagan, Artin; Dunson, David B; Lee, Jaeyong

    2013-01-01

    We propose a generalized double Pareto prior for Bayesian shrinkage estimation and inferences in linear models. The prior can be obtained via a scale mixture of Laplace or normal distributions, forming a bridge between the Laplace and Normal-Jeffreys' priors. While it has a spike at zero like the Laplace density, it also has a Student's t-like tail behavior. Bayesian computation is straightforward via a simple Gibbs sampling algorithm. We investigate the properties of the maximum a posteriori estimator, as sparse estimation plays an important role in many problems, reveal connections with some well-established regularization procedures, and show some asymptotic results. The performance of the prior is tested through simulations and an application.

  20. Natural generalized mirage mediation

    CERN Document Server

    Baer, Howard; Serce, Hasan; Tata, Xerxes

    2016-01-01

    In the supersymmetric scenario known as mirage mediation (MM), the soft SUSY breaking terms receive comparable anomaly-mediation and moduli-mediation contributions leading to the phenomenon of mirage unification. The simplest MM SUSY breaking models which are consistent with the measured Higgs mass and sparticle mass constraints are strongly disfavoured by fine-tuning considerations. However, while MM makes robust predictions for gaugino masses, the scalar sector is quite sensitive to specific mechanisms for moduli stabilization and potential uplifting. We suggest here a broader setup of generalized mirage mediation (GMM), where heretofore discrete parameters are allowed as continuous to better parametrize these other schemes. We find that natural SUSY spectra consistent with both the measured value of m(h). as well as LHC lower bounds on superpartner masses are then possible. We explicitly show that models generated from natural GMM may be beyond the reach of even high-luminosity LHC searches. In such a case...

  1. WILL THE CLIMATE CHANGE SMALLER THAN THE PROJECTION?%我国气候变化将比模式预期的小吗?

    Institute of Scientific and Technical Information of China (English)

    王会军; 王涛; 姜大膀; 富元海

    2009-01-01

    从当今国际上不同的气候系统模式模拟的全新世大暖期和末次盛冰期我国气候变化量级和复原资料结果的对比,以及从目前气候变化的趋势(包括温室气体、气温、海洋温度、海平面高度、冰川等),来评述我国区域气候未来变化的鼍级.从以上两个方面的情况看,我国区域的未来气候变化量级可能比现有模式预估的还要大.文章最后讨论了我国的气候变化脆弱区以及关键的气候变化要素问题.%The Intergovernmental panel for Climate Change(IPCC) Report Series issued stronger and stronger conclusion that the climate change in the 20~(th) century is very much likely the largest climate change in recent 1000 years and warming the 20~(th) century is attributed to the green house gases increase. Recent studies suggest that the climate change is accelerated and the future climate change may well be larger than previously projected. However, there are opposite opinions as well both abroad and domestic. This article will discuss the issue of will the future climate change in China lager or smaller than projected. Our analyses will based on the climate model behavior in simulating the last glacial maximum and the mid-Holocene climates, as well as the recent changes in temperature, sea level, green house gases, mountain glaciers, and so on. All these information seems to lead to a conclusion that the future climate change in China might larger than projected by the state-of-the-art climate models. In order to better adjust to the climate change, recognizing the key vulnerable regions to climate change is essential. The paper suggests several key vulnerable regions, including the source region of the three major rivers (Yangtze River,Yellow River, and Lantsang River) ,the Central North China, North East China, North West China, and South Eastern China. Key issues for the source region of the three rivers include the fast melting of the mountain glaciers in the

  2. Generalized adjoint systems

    CERN Document Server

    Serakos, Demetrios

    2015-01-01

    This book defines and develops the generalized adjoint of an input-output system. It is the result of a theoretical development and examination of the generalized adjoint concept and the conditions under which systems analysis using adjoints is valid. Results developed in this book are useful aids for the analysis and modeling of physical systems, including the development of guidance and control algorithms and in developing simulations. The generalized adjoint system is defined and is patterned similarly to adjoints of bounded linear transformations. Next the elementary properties of the generalized adjoint system are derived. For a space of input-output systems, a generalized adjoint map from this space of systems to the space of generalized adjoints is defined. Then properties of the generalized adjoint map are derived. Afterward the author demonstrates that the inverse of an input-output system may be represented in terms of the generalized adjoint. The use of generalized adjoints to determine bounds for ...

  3. Dentist Offices, This file contains the name, address, license number and plan participation for Maryland Medicaid dentists., Published in 2009, Smaller than 1:100000 scale, Maryland Department of Health and Mental Hygiene.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Dentist Offices dataset, published at Smaller than 1:100000 scale, was produced all or in part from Other information as of 2009. It is described as 'This file...

  4. Hydrography, 500K Great Salt Lake Shoreline --This data set represents the geographic extent of the Great Salt Lake shoreline varying water levels., Published in 1978, Smaller than 1:100000 scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Hydrography dataset, published at Smaller than 1:100000 scale, was produced all or in part from Hardcopy Maps information as of 1978. It is described as '500K...

  5. Geophysical Investigations, Scientific, UT-Oil and gas pools in the state of Utah with CO2 capacities, Published in 2006, Smaller than 1:100000 scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Geophysical Investigations, Scientific dataset, published at Smaller than 1:100000 scale as of 2006. It is described as 'UT-Oil and gas pools in the state of...

  6. Government Districts, Other, CO-To provide estimates of CO2 sequestration capacity of oil and gas pools in Colorado, Published in 2006, Smaller than 1:100000 scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Government Districts, Other dataset, published at Smaller than 1:100000 scale, was produced all or in part from Other information as of 2006. It is described...

  7. Mollusk Distribution and Habitat, Layer contains quantitative survey results of freshwater mussel in the Delaware River, between Petty Island and Chester, PA., Published in 2013, Smaller than 1:100000 scale, Pennsylvania Coastal Resources Management Program.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Mollusk Distribution and Habitat dataset, published at Smaller than 1:100000 scale, was produced all or in part from Field Survey/GPS information as of 2013. It...

  8. Assisted Living Facilities, This file contains the name, address and some licensing information for the Nursing Homes for Maryland., Published in 2010, Smaller than 1:100000 scale, Maryland Department of Health and Mental Hygiene.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Assisted Living Facilities dataset, published at Smaller than 1:100000 scale, was produced all or in part from Other information as of 2010. It is described as...

  9. Assisted Living Facilities, This file contains the name, address, contact and some licensing information for the Assisted Living Facilites for the State of Maryland., Published in 2010, Smaller than 1:100000 scale, Maryland Department of Health and Mental Hygiene.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Assisted Living Facilities dataset, published at Smaller than 1:100000 scale, was produced all or in part from Other information as of 2010. It is described as...

  10. Telephone Service Areas, TelephoneServiceAreas-This data set represents the service areas of companies providing (dial tone) telephone service in Utah., Published in 2001, Smaller than 1:100000 scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Telephone Service Areas dataset, published at Smaller than 1:100000 scale, was produced all or in part from Other information as of 2001. It is described as...

  11. Pest Locations, Plant disease and insect pest survey data aggregated to county level., Published in 2009, Smaller than 1:100000 scale, Wisconsin Department of Agriculture, Trade & Consumer Protection.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Pest Locations dataset, published at Smaller than 1:100000 scale, was produced all or in part from Field Survey/GPS information as of 2009. It is described as...

  12. Aggregate and Mineral Resources, PhosphateDeposits1988-This data set represents phosphate deposit areas in Utah., Published in 2001, Smaller than 1:100000 scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Aggregate and Mineral Resources dataset, published at Smaller than 1:100000 scale, was produced all or in part from Hardcopy Maps information as of 2001. It is...

  13. Substance Abuse, This file contains the name, address and limited licensing information for the Substance Abuse facilities in Maryland., Published in 2010, Smaller than 1:100000 scale, Maryland Department of Health and Mental Hygiene.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Substance Abuse dataset, published at Smaller than 1:100000 scale, was produced all or in part from Other information as of 2010. It is described as 'This file...

  14. Cultural Resources, RecreationAreasESRI-This data set represents the recreational areas found in Utah, including campgrounds, golf courses and ski resorts., Published in 2001, Smaller than 1:100000 scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cultural Resources dataset, published at Smaller than 1:100000 scale, was produced all or in part from Published Reports/Deeds information as of 2001. It is...

  15. On generalized extending modules

    Institute of Scientific and Technical Information of China (English)

    ZENG Qing-yi

    2007-01-01

    A module M is called generalized extending if for any submodule N of M, there is a direct summand K of M such that N≤K and K/N is singular. Any extending module and any singular module are generalized extending. Any homomorphic image of a generalized extending module is generalized extending. Any direct sum of a singular (uniform) module and a semi-simple module is generalized extending. A ring R is a right Co-H-ring ifand only ifall right R modules are generalized extending modules.

  16. 45 CFR 1302.5 - Notice for show cause and hearing.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Notice for show cause and hearing. 1302.5 Section... GRANTEES, AND FOR SELECTION OF REPLACEMENT GRANTEES General § 1302.5 Notice for show cause and hearing. (a... this chapter, to show cause why such action should not be taken. (b) The responsible HHS official...

  17. Generalized Entropy Concentration for Counts

    CERN Document Server

    Oikonomou, Kostas N

    2016-01-01

    We consider the phenomenon of entropy concentration under linear constraints in a discrete setting, using the "balls and bins" paradigm, but without the assumption that the number of balls allocated to the bins is known. Therefore instead of \\ frequency vectors and ordinary entropy, we have count vectors with unknown sum, and a certain generalized entropy. We show that if the constraints bound the allowable sums, this suffices for concentration to occur even in this setting. The concentration can be either in terms of deviation from the maximum generalized entropy value, or in terms of the norm of the difference from the maximum generalized entropy vector. Without any asymptotic considerations, we quantify the concentration in terms of various parameters, notably a tolerance on the constraints which ensures that they are always satisfied by an integral vector. Generalized entropy maximization is not only compatible with ordinary MaxEnt, but can also be considered an extension of it, as it allows us to address...

  18. General Ultrasound Imaging

    Medline Plus

    Full Text Available ... are the limitations of General Ultrasound Imaging? What is General Ultrasound Imaging? Ultrasound is safe and painless, ... through the blood vessels. top of page How is the procedure performed? For most ultrasound exams, you ...

  19. General IC Symptoms

    Science.gov (United States)

    ... IC Symptoms of IC General IC Symptoms General IC Symptoms Symptoms of interstitial cystitis (IC) differ from ... news and events. Please leave this field empty Interstitial Cystitis Association 7918 Jones Branch Drive, Suite 300 McLean, ...

  20. Delphi General Ledger -

    Data.gov (United States)

    Department of Transportation — Delphi general ledger contains the following data elements, but is not limited to the United States Standard General Ledger (USSGL) chart of accounts, stores actual,...

  1. Generalized convexity, generalized monotonicity recent results

    CERN Document Server

    Martinez-Legaz, Juan-Enrique; Volle, Michel

    1998-01-01

    A function is convex if its epigraph is convex. This geometrical structure has very strong implications in terms of continuity and differentiability. Separation theorems lead to optimality conditions and duality for convex problems. A function is quasiconvex if its lower level sets are convex. Here again, the geo­ metrical structure of the level sets implies some continuity and differentiability properties for quasiconvex functions. Optimality conditions and duality can be derived for optimization problems involving such functions as well. Over a period of about fifty years, quasiconvex and other generalized convex functions have been considered in a variety of fields including economies, man­ agement science, engineering, probability and applied sciences in accordance with the need of particular applications. During the last twenty-five years, an increase of research activities in this field has been witnessed. More recently generalized monotonicity of maps has been studied. It relates to generalized conve...

  2. Behaviour of heart rate and electrical muscle activity in the simultaneous dynamic action of larger and smaller sets of muscles in the permanent performance threshold range.

    Science.gov (United States)

    Weber, H; Naumann, H J; Jentsch, A; Tröger, B; Wunderlich, H

    1987-01-01

    This study was undertaken to assess more comprehensively and with greater differentiation the reduction in the absolute electrical muscle activity (aEA) determined by different investigations in the permanent performance threshold range of the cardiovascular system (HKS) by means of the behaviour of the aEA of the highly stressed leg muscles and little stressed forearm muscles. Six healthy, untrained male subjects operated a hand ergograph alone in one test, and, in four more tests, in combination with a constant bicycle ergometer load of 40, 60, 80, and 100 W, respectively. As a result of these tests, a relative reduction in aEA for the leg muscles and an absolute reduction in aEA for the forearm muscles could be identified in the permanent performance threshold range of the HKS. Therefore, aEA is also considered to be an indicator of general stress that can define the permanent performance threshold range of the HKS more completely. The reduction in aEA is probably an expression of a negative feedback from the cardiovascular system to the neuromuscular system induced by the central nervous system.

  3. Application of Generalized Space-Time Autoregressive Model on GDP Data in West European Countries

    Directory of Open Access Journals (Sweden)

    Nunung Nurhayati

    2012-01-01

    Full Text Available This paper provides an application of generalized space-time autoregressive (GSTAR model on GDP data in West European countries. Preliminary model is identified by space-time ACF and space-time PACF of the sample, and model parameters are estimated using the least square method. The forecast performance is evaluated using the mean of squared forecast errors (MSFEs based on the last ten actual data. It is found that the preliminary model is GSTAR(2;1,1. As a comparison, the estimation and the forecast performance are also applied to the GSTAR(1;1 model which has fewer parameter. The results showed that the ASFE of GSTAR(2;1,1 is smaller than that of the order (1;1. However, the t-test value shows that the performance is significantly indifferent. Thus, due to the parsimony principle, the GSTAR(1;1 model might be considered as a forecasting model.

  4. Forces in General Relativity

    Science.gov (United States)

    Ridgely, Charles T.

    2010-01-01

    Many textbooks dealing with general relativity do not demonstrate the derivation of forces in enough detail. The analyses presented herein demonstrate straightforward methods for computing forces by way of general relativity. Covariant divergence of the stress-energy-momentum tensor is used to derive a general expression of the force experienced…

  5. Forces in General Relativity

    Science.gov (United States)

    Ridgely, Charles T.

    2010-01-01

    Many textbooks dealing with general relativity do not demonstrate the derivation of forces in enough detail. The analyses presented herein demonstrate straightforward methods for computing forces by way of general relativity. Covariant divergence of the stress-energy-momentum tensor is used to derive a general expression of the force experienced…

  6. Generalized Poisson sigma models

    CERN Document Server

    Batalin, I; Batalin, Igor; Marnelius, Robert

    2001-01-01

    A general master action in terms of superfields is given which generates generalized Poisson sigma models by means of a natural ghost number prescription. The simplest representation is the sigma model considered by Cattaneo and Felder. For Dirac brackets considerably more general models are generated.

  7. Generalized Fourier transforms classes

    DEFF Research Database (Denmark)

    Berntsen, Svend; Møller, Steen

    2002-01-01

    The Fourier class of integral transforms with kernels $B(\\omega r)$ has by definition inverse transforms with kernel $B(-\\omega r)$. The space of such transforms is explicitly constructed. A slightly more general class of generalized Fourier transforms are introduced. From the general theory...

  8. Fossil mice and rats show isotopic evidence of niche partitioning and change in dental ecomorphology related to dietary shift in Late Miocene of Pakistan.

    Science.gov (United States)

    Kimura, Yuri; Jacobs, Louis L; Cerling, Thure E; Uno, Kevin T; Ferguson, Kurt M; Flynn, Lawrence J; Patnaik, Rajeev

    2013-01-01

    Stable carbon isotope analysis in tooth enamel is a well-established approach to infer C3 and C4 dietary composition in fossil mammals. The bulk of past work has been conducted on large herbivorous mammals. One important finding is that their dietary habits of fossil large mammals track the late Miocene ecological shift from C3 forest and woodland to C4 savannah. However, few studies on carbon isotopes of fossil small mammals exist due to limitations imposed by the size of rodent teeth, and the isotopic ecological and dietary behaviors of small mammals to climate change remain unknown. Here we evaluate the impact of ecological change on small mammals by fine-scale comparisons of carbon isotope ratios (δ(13)C) with dental morphology of murine rodents, spanning 13.8 to ∼2.0 Ma, across the C3 to C4 vegetation shift in the Miocene Siwalik sequence of Pakistan. We applied in-situ laser ablation GC-IRMS to lower first molars and measured two grazing indices on upper first molars. Murine rodents yield a distinct, but related, record of past ecological conditions from large herbivorous mammals, reflecting available foods in their much smaller home ranges. In general, larger murine species show more positive δ(13)C values and have higher grazing indices than smaller species inhabiting the same area at any given age. Two clades of murine rodents experienced different rates of morphological change. In the faster-evolving clade, the timing and trend of morphological innovations are closely tied to consumption of C4 diet during the vegetation shift. This study provides quantitative evidence of linkages among diet, niche partitioning, and dental morphology at a more detailed level than previously possible.

  9. Fossil mice and rats show isotopic evidence of niche partitioning and change in dental ecomorphology related to dietary shift in Late Miocene of Pakistan.

    Directory of Open Access Journals (Sweden)

    Yuri Kimura

    Full Text Available Stable carbon isotope analysis in tooth enamel is a well-established approach to infer C3 and C4 dietary composition in fossil mammals. The bulk of past work has been conducted on large herbivorous mammals. One important finding is that their dietary habits of fossil large mammals track the late Miocene ecological shift from C3 forest and woodland to C4 savannah. However, few studies on carbon isotopes of fossil small mammals exist due to limitations imposed by the size of rodent teeth, and the isotopic ecological and dietary behaviors of small mammals to climate change remain unknown. Here we evaluate the impact of ecological change on small mammals by fine-scale comparisons of carbon isotope ratios (δ(13C with dental morphology of murine rodents, spanning 13.8 to ∼2.0 Ma, across the C3 to C4 vegetation shift in the Miocene Siwalik sequence of Pakistan. We applied in-situ laser ablation GC-IRMS to lower first molars and measured two grazing indices on upper first molars. Murine rodents yield a distinct, but related, record of past ecological conditions from large herbivorous mammals, reflecting available foods in their much smaller home ranges. In general, larger murine species show more positive δ(13C values and have higher grazing indices than smaller species inhabiting the same area at any given age. Two clades of murine rodents experienced different rates of morphological change. In the faster-evolving clade, the timing and trend of morphological innovations are closely tied to consumption of C4 diet during the vegetation shift. This study provides quantitative evidence of linkages among diet, niche partitioning, and dental morphology at a more detailed level than previously possible.

  10. Do mothers prefer helpers or smaller litters? Birth sex ratio and litter size adjustment in cotton-top tamarins (Saguinus oedipus).

    Science.gov (United States)

    Boulton, Rebecca A; Fletcher, Alison W

    2015-02-01

    Sex allocation theory has been a remarkably productive field in behavioral ecology with empirical evidence regularly supporting quantitative theoretical predictions. Across mammals in general and primates in particular, however, support for the various hypotheses has been more equivocal. Population-level sex ratio biases have often been interpreted as supportive, but evidence for small-scale facultative adjustment has rarely been found. The helper repayment (HR) also named the local resource enhancement (LRE) hypothesis predicts that, in cooperatively breeding species, mothers invest more in the sex which assists with rearing future offspring and that this bias will be more pronounced in mothers who require extra assistance (i.e., due to inexperience or a lack of available alloparents). We tested these hypotheses in captive cotton-top tamarins (Saguinus oedipus) utilizing the international studbook and birth records obtained through a questionnaire from ISIS-registered institutions. Infant sex, litter size, mother's age, parity, and group composition (presence of nonreproductive subordinate males and females) were determined from these records. The HR hypothesis was supported over the entire population, which was significantly biased toward males (the "helpful" sex). We found little support for helper repayment at the individual level, as primiparous females and those in groups without alloparents did not exhibit more extreme tendencies to produce male infants. Primiparous females were, however, more likely to produce singleton litters. Singleton births were more likely to be male, which suggests that there may be an interaction between litter size adjustment and sex allocation. This may be interpreted as supportive of the HR hypothesis, but alternative explanations at both the proximate and ultimate levels are possible. These possibilities warrant further consideration when attempting to understand the ambiguous results of primate sex ratio studies so far.

  11. Generalization Rough Set Theory

    Institute of Scientific and Technical Information of China (English)

    XIAO Di; ZHANG Jun-feng; HU Shou-song

    2008-01-01

    In order to avoid the discretization in the classical rough set theory, a generlization rough set theory is proposed.At first, the degree of general importance of an attribute and attribute subsets are presented.Then, depending on the degree of general importance of attribute, the space distance can be measured with weighted method.At last, a generalization rough set theory based on the general near neighborhood relation is proposed.The proposed theory partitions the universe into the tolerant modules, and forms lower approximation and upper approximation of the set under general near neighborhood relationship, which avoids the discretization in Pawlak's rough set theory.

  12. Dynamics of generalized coherent states

    CERN Document Server

    De Martino, S; Illuminati, F; De Martino, S; De Siena, S; Illuminati, F

    1995-01-01

    We show that generalized coherent states follow Schr\\"{o}dinger dynamics in time-dependent potentials. The normalized wave-packets follow a classical evolution without spreading; in turn, the Schr\\"{o}dinger potential depends on the state through the classical trajectory. This feedback mechanism with continuous dynamical re-adjustement allows the packets to remain coherent indefinetely.

  13. Probing General Relativity with Accreting Black Holes

    CERN Document Server

    Fabian, A C

    2012-01-01

    Most of the X-ray emission from luminous accreting black holes emerges from within 20 gravitational radii. The effective emission radius is several times smaller if the black hole is rapidly spinning. General Relativistic effects can then be very important. Large spacetime curvature causes strong lightbending and large gravitational redshifts. The hard X-ray, power-law-emitting corona irradiates the accretion disc generating an X-ray reflection component. Atomic features in the reflection spectrum allow gravitational redshifts to be measured. Time delays between observed variations in the power-law and the reflection spectrum (reverberation) enable the physical scale of the reflecting region to be determined. The relative strength of the reflection and power-law continuum depends on light bending. All of these observed effects enable the immediate environment of the black hole where the effects of General Relativity are on display to be probed and explored.

  14. Pineapple and banana pectins comprise fewer homogalacturonan building blocks with a smaller degree of polymerization as compared with yellow passion fruit and lemon pectins: implication for gelling properties.

    Science.gov (United States)

    Yapo, Beda M

    2009-04-13

    Pectins are viewed as multiblock cobiopolymers of different pectic polysaccharides, notably, homogalacturonan (HG) and rhamnogalacturonan I (RG I). Furthermore, on the basis of HGs isolated from different (pectins from) dicot cell walls, HG is supposed to have an average degree of polymerization (DP) of approximately 100 irrespective of the plant source. To validate or invalidate these suppositions, pectins from both monocot (pineapple and banana) and dicot (yellow passion fruit and lemon) cell walls were examined. The results show that all the extracted pectins comprise HGs as well as type I and II arabinogalactan side chain-containing RGs I, but of significantly (p properties of pectin.

  15. Energy dissipation at the silica glass/compressed aerogel interface: The fate of Wild 2 mineral grains and fragments smaller than ~100 nm

    Science.gov (United States)

    Rietmeijer, Frans J. M.

    2016-07-01

    Allocation FC6,0,10,0,26 from Stardust track 10 shows a slightly wavy silica glass/compressed silica aerogel interface exposing a patchwork of compressed silica aerogel domains and domains of silica glass with embedded Wild 2 materials in ultra-thin TEM sections. This interface is where molten silica encountered compressed silica aerogel at temperatures allocation form core-ring grains with a gap between the iron core and a surrounding ring of thermally modified aerogel. This structure was caused when rapid, thermal expansion of the core heated the surrounding compressed aerogel that upon rapid cooling remained fixed in place while the iron core shrank back to its original size. The well-known volume expansion of pure iron allowed reconstruction of the quench temperature for individual core-ring grains. These temperatures showed the small scale of thermal energy loss at the silica glass/compressed silica aerogel interface. The data support fragmentation of olivine, plagioclase, and iron and Fe ± low-Ni grains from comet 81P/Wild 2 during hypervelocity capture.

  16. Chinese hotel general managers' perspectives on energy-saving practices

    Science.gov (United States)

    Zhu, Yidan

    As hotels' concern about sustainability and budget-control is growing steadily, energy-saving issues have become one of the important management concerns hospitality industry face. By executing proper energy-saving practices, previous scholars believed that hotel operation costs can decrease dramatically. Moreover, they believed that conducting energy-saving practices may eventually help the hotel to gain other benefits such as an improved reputation and stronger competitive advantage. The energy-saving issue also has become a critical management problem for the hotel industry in China. Previous research has not investigated energy-saving in China's hotel segment. To achieve a better understanding of the importance of energy-saving, this document attempts to present some insights into China's energy-saving practices in the tourist accommodations sector. Results of the study show the Chinese general managers' attitudes toward energy-saving issues and the differences among the diverse hotel managers who responded to the study. Study results indicate that in China, most of the hotels' energy bills decrease due to the implementation of energy-saving equipments. General managers of hotels in operation for a shorter period of time are typically responsible for making decisions about energy-saving issues; older hotels are used to choosing corporate level concerning to this issue. Larger Chinese hotels generally have official energy-saving usage training sessions for employees, but smaller Chinese hotels sometimes overlook the importance of employee training. The study also found that for the Chinese hospitality industry, energy-saving practices related to electricity are the most efficient and common way to save energy, but older hotels also should pay attention to other ways of saving energy such as water conservation or heating/cooling system.

  17. Energy dissipation at the silica glass/compressed aerogel interface: The fate of Wild 2 mineral grains and fragments smaller than ~100 nm

    Science.gov (United States)

    Rietmeijer, Frans J. M.

    2016-10-01

    Allocation FC6,0,10,0,26 from Stardust track 10 shows a slightly wavy silica glass/compressed silica aerogel interface exposing a patchwork of compressed silica aerogel domains and domains of silica glass with embedded Wild 2 materials in ultra-thin TEM sections. This interface is where molten silica encountered compressed silica aerogel at temperatures glass. A Mg-, Al-, Ca-, K-bearing silica globule moved independently as a single object. Two clusters of pure iron, low-Ni iron, and low-Ni, low-sulfur Fe-Ni-S grains also survived intact and came to rest right at the interface between silica glass/compressed silica aerogel. There are numerous Fe-Ni-S nanograins scattered throughout MgO-rich magnesiosilica glass, but compositionally similar Fe-Ni-S are also found in the compressed silica aerogel, where they are not supposed to be. This work could not establish how deep they had penetrated the aerogel. Iron nanograins in this allocation form core-ring grains with a gap between the iron core and a surrounding ring of thermally modified aerogel. This structure was caused when rapid, thermal expansion of the core heated the surrounding compressed aerogel that upon rapid cooling remained fixed in place while the iron core shrank back to its original size. The well-known volume expansion of pure iron allowed reconstruction of the quench temperature for individual core-ring grains. These temperatures showed the small scale of thermal energy loss at the silica glass/compressed silica aerogel interface. The data support fragmentation of olivine, plagioclase, and iron and Fe ± low-Ni grains from comet 81P/Wild 2 during hypervelocity capture.

  18. Non-syndromic occurrence of true generalized microdontia with mandibular mesiodens - a rare case.

    Science.gov (United States)

    Bargale, Seema D; Kiran, Shital D P

    2011-10-28

    Abnormalities in size of teeth and number of teeth are occasionally recorded in clinical cases. True generalized microdontia is rare case in which all the teeth are smaller than normal. Mesiodens is commonly located in maxilary central incisor region and uncommon in the mandible. In the present case a 12 year-old boy was healthy; normal in appearance and the medical history was noncontributory. The patient was examined and found to have permanent teeth that were smaller than those of the average adult teeth. The true generalized microdontia was accompanied by mandibular mesiodens. This is a unique case report of non-syndromic association of mandibular hyperdontia with true generalized microdontia.

  19. Doing more with less: General quantitative properties of urban metabolism

    Science.gov (United States)

    Bettencourt, L. M.

    2011-12-01

    The fast urbanization of human societies worldwide is bringing about some of the greatest historic changes in our relationship with the Earth's natural environments, with potentially irreversible and unpredictable consequences. From the human point of view urbanization is intimately connected to socio-economic development, transitioning people away from subsistence agriculture and integrating them into large-scale diversified economies. These processes change the demands placed by human societies on natural environments in terms of energy and material flows, land use and other effects associated with climate change (CO2 emissions) and loss of biodiversity. Urbanization offers at once a host of new problems and solutions. On the one hand living standards associated with developed urbanized societies are higher, usually implying greater consumption of energy and materials. On the other hand cities allow and encourage the pursuit of more efficient solutions to human settlement and transportation and emphasize to a growing extent information and creativity as measures of human socioeconomic wellbeing. The concept of urban metabolism - the relationship between energy and material resource use to socioeconomic output - offers an integrated view of these tradeoffs. While the metaphor has a long history, the increasing availability of data on urban systems worldwide is opening new opportunities in making the concept quantitative and a useful instrument of scientific analysis. In this talk I will discuss a large amount of quantitative evidence from urban systems worldwide showing general patterns in energy use, infrastructure and socioeconomic output, which together define what cities are. I will show how cities can save on material infrastructure by using distribution networks more intensely and will detail some of the emerging patterns in urban energy usage and CO2 emissions for several nations. I will also show that larger cities show on average display higher

  20. Beurling generalized numbers

    CERN Document Server

    Diamond, Harold G; Cheung, Man Ping

    2016-01-01

    "Generalized numbers" is a multiplicative structure introduced by A. Beurling to study how independent prime number theory is from the additivity of the natural numbers. The results and techniques of this theory apply to other systems having the character of prime numbers and integers; for example, it is used in the study of the prime number theorem (PNT) for ideals of algebraic number fields. Using both analytic and elementary methods, this book presents many old and new theorems, including several of the authors' results, and many examples of extremal behavior of g-number systems. Also, the authors give detailed accounts of the L^2 PNT theorem of J. P. Kahane and of the example created with H. L. Montgomery, showing that additive structure is needed for proving the Riemann hypothesis. Other interesting topics discussed are propositions "equivalent" to the PNT, the role of multiplicative convolution and Chebyshev's prime number formula for g-numbers, and how Beurling theory provides an interpretation of the ...

  1. Conformal General Relativity

    CERN Document Server

    Pervushin, V

    2001-01-01

    The inflation-free solution of problems of the modern cosmology (horizon, cosmic initial data, Planck era, arrow of time, singularity,homogeneity, and so on) is considered in the conformal-invariant unified theory given in the space with geometry of similarity where we can measure only the conformal-invariant ratio of all quantities. Conformal General Relativity is defined as the $SU_c(3)\\times SU(2)\\times U(1)$-Standard Model where the dimensional parameter in the Higgs potential is replaced by a dilaton scalar field described by the negative Penrose-Chernikov-Tagirov action. Spontaneous SU(2) symmetry breaking is made on the level of the conformal-invariant angle of the dilaton-Higgs mixing, and it allows us to keep the structure of Einstein's theory with the equivalence principle. We show that the lowest order of the linearized equations of motion solves the problems mentioned above and describes the Cold Universe Scenario with the constant temperature T and z-history of all masses with respect to an obser...

  2. [General review of rhinolithiases].

    Science.gov (United States)

    Kharoubi, S

    2008-02-01

    The aim of this study was to analyze the clinical presentation and characteristics of rhinolithiasis, a rare and forgotten entity. Between 1990 and 2007, 20 cases of rhinolithiasis presented for consultation. The clinical course noted chronic nasal discharge associated with nasal obstruction. The protocol was the same for all patients: history of disease, meticulous endonasal endoscopy and plain radiography (+/-CT scan). Rhinolithiasis was found in adults (55%), females, patients living in rural areas (66%) with unfavorable socioeconomic conditions. The diagnosis delay varied between six months and eight years. The examination showed the rhinolith in the form of a grey concretion, primarily unilateral and on the right-hand side in 60% of the patients. Only one bilateral case presented following destruction of the posterior nasal septum. The rhinolith measured between 5 and 50mm in diameter with only three associated foreign bodies (15%). The rhinolith was extracted through the natural pathways under local anesthesia in 60% of the cases. Complications were rare (epistaxis 10%) and favorable progression without recurrence was generally observed after a mean 16 months of follow-up (range, six months to 11 years). Chronic nasal discharge without a history of rhinologic disease requires an endonasal examination under good conditions after retraction. Rhinolithiasis is easily recognized, in particular on imaging studies. Treatment is simple and curative in the majority of cases.

  3. How General Is Holography?

    CERN Document Server

    Riegler, Max

    2016-01-01

    In this thesis I explore the generality of the holographic principle in 2+1 (bulk) dimensions by looking at the possibility of having holographic correspondences for non-AdS (higher-spin) spacetimes. The first part focuses on Lobachevsky spacetimes with $\\mathfrak{sl}(4,\\mathbb{R})$ as well as $\\mathcal{W}^{(2)}_N$ symmetries, the asymptotic symmetry algebras and their unitary representations. This results in a family of unitary $\\mathcal{W}^{(2)}_N$ models that can have both small and large central charge. The focus of the second part is a possible holographic correspondence in asymptotically flat spacetimes. This part covers limits from known AdS$_3$ results to flat space as well as a NO-GO result that forbids having flat space, higher-spins and unitarity at the same time. In addition this part shows how to consistently add (higher-spin) chemical potentials to flat space. As a non-trivial check of a holographic correspondence in flat space I provide a way to determine entanglement entropy (as well as therma...

  4. Natural generalized mirage mediation

    Science.gov (United States)

    Baer, Howard; Barger, Vernon; Serce, Hasan; Tata, Xerxes

    2016-12-01

    In the supersymmetric scenario known as mirage mediation (MM), the soft supersymmetry (SUSY) breaking terms receive comparable anomaly-mediation and moduli-mediation contributions leading to the phenomenon of mirage unification. The simplest MM SUSY breaking models which are consistent with the measured Higgs mass and sparticle mass constraints are strongly disfavored by fine-tuning considerations. However, while MM makes robust predictions for gaugino masses, the scalar sector is quite sensitive to specific mechanisms for moduli stabilization and potential uplifting. We suggest here a broader setup of generalized mirage mediation (GMM), where heretofore discrete parameters are allowed as continuous to better parametrize these other schemes. We find that natural SUSY spectra consistent with both the measured value of mh as well as LHC lower bounds on superpartner masses are then possible. We explicitly show that models generated from natural GMM may be beyond the reach of even high-luminosity LHC searches. In such a case, the proposed International Linear e+e- Collider will be required for natural SUSY discovery via higgsino pair production reactions. We also outline prospects for detection of higgsino-like WIMPs from natural GMM.

  5. Binding studies of alpha-GalNAc-specific lectins to the alpha-GalNAc (Tn-antigen) form of porcine submaxillary mucin and its smaller fragments.

    Science.gov (United States)

    Dam, Tarun K; Gerken, Thomas A; Cavada, Benildo S; Nascimento, Kyria S; Moura, Tales R; Brewer, C Fred

    2007-09-21

    Isothermal titration microcalorimetry (ITC) and hemagglutination inhibition measurements demonstrate that a chemically and enzymatically prepared form of porcine submaxillary mucin that possesses a molecular mass of approximately 10(6) daltons and approximately 2300 alpha-GalNAc residues (Tn-PSM) binds to the soybean agglutinin (SBA) with a K(d) of 0.2 nm, which is approximately 10(6)-fold enhanced affinity relative to GalNAcalpha1-O-Ser (Tn), the pancarcinoma carbohydrate antigen. The enzymatically derived 81 amino acid tandem repeat domain of Tn-PSM containing approximately 23 alpha-GalNAc residues binds with approximately 10(3)-fold enhanced affinity, while the enzymatically derived 38/40 amino acid cleavage product(s) of Tn-PSM containing approximately 11-12 alpha-GalNAc residues shows approximately 10(2)-fold enhanced affinity. A natural carbohydrate decorated form of PSM (Fd-PSM) containing 40% of the core 1 blood group type A tetrasaccharide, and 58% peptide-linked GalNAcalpha1-O-Ser/Thr residues, with 45% of the peptide-linked alpha-GalNAc residues linked alpha-(2,6) to N-glycolylneuraminic acid, shows approximately 10(4) enhanced affinity for SBA. Vatairea macrocarpa lectin (VML), which is also a GalNAc binding lectin, displays a similar pattern of binding to the four forms of PSM, although there are quantitative differences in its affinities as compared with SBA. The higher affinities of SBA and VML for Tn-PSM relative to Fd-PSM indicate the importance of carbohydrate composition and epitope density of mucins on their affinities for lectins. The higher affinities of SBA and VML for Tn-PSM relative to its two shorter chain analogs demonstrate that the length of a mucin polypeptide and hence total carbohydrate valence determines the affinities of the three Tn-PSM analogs. The results suggest a binding model in which lectin molecules "bind and jump" from alpha-GalNAc residue to alpha-GalNAc residue along the polypeptide chain of Tn-PSM before dissociating

  6. A generalization of vortex lines

    CERN Document Server

    Fecko, Marian

    2016-01-01

    Helmholtz theorem states that, in ideal fluid, vortex lines move with the fluid. Another Helmholtz theorem adds that strength of a vortex tube is constant along the tube. The lines may be regarded as integral surfaces of an 1-dimensional integrable distribution (given by the vorticity 2-form). In general setting of theory of integral invariants, due to Poincare and Cartan, one can find $d$-dimensional integrable distribution whose integral surfaces show both properties of vortex lines: they move with (abstract) fluid and, for appropriate generalization of vortex tube, strength of the latter is constant along the tube.

  7. Remarks on generalized toric codes

    CERN Document Server

    Little, John B

    2011-01-01

    This note presents some new information on how the minimum distance of the generalized toric code corresponding to a fixed set of integer lattice points S in R^2 varies with the base field. The main results show that in some cases, over sufficiently large fields, the minimum distance of the code corresponding to a set S will be the same as that of the code corresponding to the convex hull of S. In an example, we will also discuss a [49,12,28] generalized toric code over GF(8), better than any previously known code according to M. Grassl's online tables, as of July 2011.

  8. Unsupervised Learning and Generalization

    DEFF Research Database (Denmark)

    Hansen, Lars Kai; Larsen, Jan

    1996-01-01

    The concept of generalization is defined for a general class of unsupervised learning machines. The generalization error is a straightforward extension of the corresponding concept for supervised learning, and may be estimated empirically using a test set or by statistical means-in close analogy ...... with supervised learning. The empirical and analytical estimates are compared for principal component analysis and for K-means clustering based density estimation...

  9. General surgery career resource.

    Science.gov (United States)

    Parsee, Ana M; Ross, Sharona B; Gantt, Nancy L; Kichler, Kandace; Hollands, Celeste

    2013-11-01

    General surgery residency training can lead to a rewarding career in general surgery and serve as the foundation for careers in several surgical subspecialties. It offers broad-based training with exposure to the cognitive and technical aspects of several surgical specialties and prepares graduating residents for a wide range of career paths. This career development resource discusses the training aspects of general surgery. Copyright © 2013 Elsevier Inc. All rights reserved.

  10. Generalized Group Signature Scheme

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The concept of generalized group signature scheme will bepresent. Based on the generalized secret sharing scheme proposed by Lin and Ha rn, a non-interactive approach is designed for realizing such generalized group signature scheme. Using the new scheme, the authorized subsets of the group in w hich the group member can cooperate to produce the valid signature for any messa ge can be randomly specified

  11. Generalized quasi variational inequalities

    Energy Technology Data Exchange (ETDEWEB)

    Noor, M.A. [King Saud Univ., Riyadh (Saudi Arabia)

    1996-12-31

    In this paper, we establish the equivalence between the generalized quasi variational inequalities and the generalized implicit Wiener-Hopf equations using essentially the projection technique. This equivalence is used to suggest and analyze a number of new iterative algorithms for solving generalized quasi variational inequalities and the related complementarity problems. The convergence criteria is also considered. The results proved in this paper represent a significant improvement and refinement of the previously known results.

  12. Do the Young Live in a "Smaller World" Than the Old? Age-Specific Degrees of Separation in a Large-Scale Mobile Communication Network

    CERN Document Server

    Dong, Yuxiao; Chawla, Nitesh V

    2016-01-01

    That any two persons are separated by a relatively small number of intermediary contacts -- the "small-world" phenomenon -- is a surprising but well established regularity in human social networks. To date, network science has ignored the question of whether the small world phenomenon manifests itself in similar ways across dyadic classes defined by individual traits, such as age or sex. To address this gap in the literature, we explore the phenomenon of "age-specific small worlds" by employing a mobile phone network built from billions of communication events approximating interaction patterns at a societal scale. We observe the average distance between any pair of users is 9.52, corresponding to nine-and-a-half degrees of separation. More importantly, we show that there is a systematic relationship between age and the average distance connecting that person to others, with some age groups falling below this average quantity while others falling above. Young people live in the "smallest world," being separat...

  13. Percutaneous ethanol injection therapy is comparable to radiofrequency ablation in hepatocellular carcinoma smaller than 1.5 cm: A matched case-control comparative analysis.

    Science.gov (United States)

    Yu, Su Jong; Yoon, Jung-Hwan; Lee, Jeong Min; Lee, Jae Young; Kim, Se Hyung; Cho, Young Youn; Yoo, Jeong-Ju; Lee, Minjong; Lee, Dong Hyeon; Cho, Yuri; Cho, Eun Ju; Lee, Jeong-Hoon; Kim, Yoon Jun; Kim, Chung Yong

    2016-08-01

    Although percutaneous ethanol injection therapy (PEIT) is best indicated for patients with small hepatocellular carcinoma (HCC), the survival advantage of PEIT needs confirmation in real-world practice. This study was approved by the institutional review board, and the informed consent was waived. The study included 535 consecutive patients with newly diagnosed early stage (Barcelona Clinic Liver Cancer [BCLC] 0 or A) HCC who underwent initially radiofrequency ablation (RFA) (n = 288) or PEIT (n = 247) from January 2005 to December 2010. The primary outcome was overall survival (OS) and the secondary outcome was time to progression (TTP). The longest diameters of tumors of the groups differed significantly and larger for RFA group than PEIT group (P HR], 1.690; 95% confidence interval [CI], 0.828-3.449; P = 0.149) and time to progression (HR, 1.160; 95% CI, 0.773-1.740; P = 0.474). PEIT and RFA show equal effectiveness in treating HCCs <1.5 cm in terms of OS and time to progression.

  14. Academy of General Dentistry

    Science.gov (United States)

    ... continuing education. BECOME A FELLOW OR MASTER Continuing Education Access the latest CE opportunities, including live and on-demand webinars, specifically designed for the general dentist. BROWSE ...

  15. Generalized Fibonacci zone plates

    CERN Document Server

    Ke, Jie; Zhu, Jianqiang

    2015-01-01

    We propose a family of zone plates which are produced by the generalized Fibonacci sequences and their axial focusing properties are analyzed in detail. Compared with traditional Fresnel zone plates, the generalized Fibonacci zone plates present two axial foci with equal intensity. Besides, we propose an approach to adjust the axial locations of the two foci by means of different optical path difference, and further give the deterministic ratio of the two focal distances which attributes to their own generalized Fibonacci sequences. The generalized Fibonacci zone plates may allow for new applications in micro and nanophotonics.

  16. Map Service Showing Geology and Geologic Provinces of South Asia

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The geology data set for this map includes arcs, polygons, and labels that outline and describe the general geologic age and rock type for South Asia. The geologic...

  17. Decay of ground motion peak values is faster for smaller magnitude events: investigation of the role played by the attenuation and the scattering effects

    Science.gov (United States)

    Dujardin, A.; Courboulex, F.; Causse, M.; Traversa, P.

    2013-12-01

    The decay of ground motion peak values (PGA, PGV ...) with distance is a parameter of great importance in the prediction of ground motion for seismic hazard assessment. This decay appears to be dependent on the size of the earthquakes: faster for small than for large earthquakes. This has been observed many times in real databases and is now included in most of the Ground Motion Prediction Equations (GMPEs). Nevertheless, the physical causes of these differences have never been clearly identified. In order to understand and quantify this effect we explore the influence two of major processes: the anelastic attenuation and the scattering effects. We first performed synthetic tests using the stochastic simulation program SMSIM (Boore 2003) and we generate temporal series at different distances and different magnitudes for different values of the quality factor (Q(f)) which describe the anelastic attenuation. We observe that the decay of ground motion peak values (especially PGA and PGV) is strongly dependent on the spectral shape of the Fourier spectrum. Due to the fact that the small earthquakes have higher frequency content, they are more affected by attenuation than larger earthquakes, and therefore the decay of PGA with distance is faster. We propose an analytical formulation that predicts this effect with a given stress drop and a Q factor value and assuming an omega square spectrum for the source. We then test the influence of the combination of source and path effects (i.e. interactions between Green and source functions) and the generation of constructive and destructive interferences in complex medium. We realized simulations by means of the discrete wave number technique in a 1D layered medium. If the medium is complex enough, interactions between Green's and source function lead to constructive interferences. This effect is more important when the source duration is longer (i.e. the magnitude is important), and we show that even without anelastic

  18. 20 CFR 416.1821 - Showing that you are married when you apply for SSI.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Showing that you are married when you apply for SSI. 416.1821 Section 416.1821 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL... Showing that you are married when you apply for SSI. (a) General rule: Proof is unnecessary. If you tell...

  19. 20 CFR 416.1826 - Showing that you are not married when you apply for SSI.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Showing that you are not married when you apply for SSI. 416.1826 Section 416.1826 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL... Showing that you are not married when you apply for SSI. (a) General rule: Proof is unnecessary. If you do...

  20. 32 CFR 552.78 - “Show cause” hearing.

    Science.gov (United States)

    2010-07-01

    ....78 “Show cause” hearing. Before suspending the solicitation privilege, the company and the agent will have a chance to show cause why the action should not be taken. “Show cause” is an opportunity for...

  1. Food Safety Not Always on Menu of TV Cooking Shows

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_161980.html Food Safety Not Always on Menu of TV Cooking Shows ... shows. They also noted whether the shows mentioned food safety. The findings were published in the November-December ...

  2. On Generalized Bell Polynomials

    Directory of Open Access Journals (Sweden)

    Roberto B. Corcino

    2011-01-01

    Full Text Available It is shown that the sequence of the generalized Bell polynomials Sn(x is convex under some restrictions of the parameters involved. A kind of recurrence relation for Sn(x is established, and some numbers related to the generalized Bell numbers and their properties are investigated.

  3. Generalizing Experimental Findings

    Science.gov (United States)

    2015-06-01

    new method using propensity score stratified sampling. Journal of Research on Educational Effectiveness 7 114–135. 11 ...Generalizing Experimental Findings Judea Pearl University of California, Los Angeles Computer Science Department Los Angeles, CA, 90095-1596, USA...Selection Bias The classical problem of generalizing experimental findings from the trial sample to the population as a whole, also known as the problem

  4. Assessment of General Education

    Science.gov (United States)

    Furman, Tanya

    2013-01-01

    The assessment of general education is often approached through broad surveys or standardized instruments that fail to capture the learning goals most faculty members desire for this portion of the curriculum. The challenge in remedying this situation lies, first, in defining general education in meaningful ways that can be both articulated and…

  5. Communication: General Semantics Perspectives.

    Science.gov (United States)

    Thayer, Lee, Ed.

    This book contains the edited papers from the eleventh International Conference on General Semantics, titled "A Search for Relevance." The conference questioned, as a central theme, the relevance of general semantics in a world of wars and human misery. Reacting to a fundamental Korzybski-ian principle that man's view of reality is distorted by…

  6. Reliability Generalization: "Lapsus Linguae"

    Science.gov (United States)

    Smith, Julie M.

    2011-01-01

    This study examines the proposed Reliability Generalization (RG) method for studying reliability. RG employs the application of meta-analytic techniques similar to those used in validity generalization studies to examine reliability coefficients. This study explains why RG does not provide a proper research method for the study of reliability,…

  7. Certificateless Generalized Signcryption

    Science.gov (United States)

    Ji, Huifang; Han, Wenbao; Zhao, Long

    Generalized Signcryption is a fresh cryptographic primitive that not only can obtain encryption and signature in a single operation, but also provide encryption or signature model alone when needed. This paper proposed a formal definition of certificateless generalized signcryption(CLGSC), then provide the security model of CLGSC. A concrete CLGSC scheme is also given in this paper.

  8. On generalized topological spaces

    OpenAIRE

    Piȩkosz, Artur

    2009-01-01

    In this paper a systematic study of the category GTS of generalized topological spaces (in the sense of H. Delfs and M. Knebusch) and their strictly continuous mappings begins. Some completeness and cocompleteness results are achieved. Generalized topological spaces help to reconstruct the important elements of the theory of locally definable and weakly definable spaces in the wide context of weakly topological structures.

  9. Generalizing: The descriptive struggle

    Directory of Open Access Journals (Sweden)

    Barney G. Glaser, Ph.D.; Hon Ph.D.

    2006-11-01

    Full Text Available The literature is not kind to the use of descriptive generalizations. Authors struggle and struggle to find and rationalize a way to use them and then fail in spite of trying a myriad of work-arounds. And then we have Lincoln and Guba’s famous statement: “The only generalization is: there is no generalization” in referring to qualitative research. (op cit, p. 110 They are referring to routine QDA yielding extensive descriptions, but which tacitly include conceptual generalizations without any real thought of knowledge about them. In this chapter I wish to explore this struggle for the purpose of explaining that the various contra arguments to using descriptive generalizations DO NOT apply to the ease of using conceptual generalizations yielded in SGT and especially FGT. I will not argue for the use of descriptive generalization. I agree with Lincoln and Guba with respect to QDA, “the only generalization is: there is no generalization.” It is up to the QDA methodologists, of whom there are many; to continue the struggle and I wish them well.

  10. Generalized connectivity of graphs

    CERN Document Server

    Li, Xueliang

    2016-01-01

    Noteworthy results, proof techniques, open problems and conjectures in generalized (edge-) connectivity are discussed in this book. Both theoretical and practical analyses for generalized (edge-) connectivity of graphs are provided. Topics covered in this book include: generalized (edge-) connectivity of graph classes, algorithms, computational complexity, sharp bounds, Nordhaus-Gaddum-type results, maximum generalized local connectivity, extremal problems, random graphs, multigraphs, relations with the Steiner tree packing problem and generalizations of connectivity. This book enables graduate students to understand and master a segment of graph theory and combinatorial optimization. Researchers in graph theory, combinatorics, combinatorial optimization, probability, computer science, discrete algorithms, complexity analysis, network design, and the information transferring models will find this book useful in their studies.

  11. Generalized Kahler geometry

    CERN Document Server

    Gualtieri, Marco

    2010-01-01

    Generalized Kahler geometry is the natural analogue of Kahler geometry, in the context of generalized complex geometry. Just as we may require a complex structure to be compatible with a Riemannian metric in a way which gives rise to a symplectic form, we may require a generalized complex structure to be compatible with a metric so that it defines a second generalized complex structure. We explore the fundamental aspects of this geometry, including its equivalence with the bi-Hermitian geometry on the target of a 2-dimensional sigma model with (2,2) supersymmetry, as well as the relation to holomorphic Dirac geometry and the resulting derived deformation theory. We also explore the analogy between pre-quantum line bundles and gerbes in the context of generalized Kahler geometry.

  12. General relativity and cosmology

    CERN Document Server

    Bucher, Martin

    2015-01-01

    This year marks the hundredth anniversary of Einstein's 1915 landmark paper "Die Feldgleichungen der Gravitation" in which the field equations of general relativity were correctly formulated for the first time, thus rendering general relativity a complete theory. Over the subsequent hundred years physicists and astronomers have struggled with uncovering the consequences and applications of these equations. This contribution, which was written as an introduction to six chapters dealing with the connection between general relativity and cosmology that will appear in the two-volume book "One Hundred Years of General Relativity: From Genesis and Empirical Foundations to Gravitational Waves, Cosmology and Quantum Gravity," endeavors to provide a historical overview of the connection between general relativity and cosmology, two areas whose development has been closely intertwined.

  13. Inductive, Analogical, and Communicative Generalization

    Directory of Open Access Journals (Sweden)

    Adri Smaling

    2003-03-01

    Full Text Available Three forms of inductive generalization - statistical generalization, variation-based generalization and theory-carried generalization - are insufficient concerning case-to-case generalization, which is a form of analogical generalization. The quality of case-to-case generalization needs to be reinforced by setting up explicit analogical argumentation. To evaluate analogical argumentation six criteria are discussed. Good analogical reasoning is an indispensable support to forms of communicative generalization - receptive and responsive (participative generalization — as well as exemplary generalization.

  14. Northwest Europe`s operators show creativity in new developments

    Energy Technology Data Exchange (ETDEWEB)

    Knott, D.

    1997-08-25

    Northwest Europe`s offshore operators have boosted their oil and gas production dramatically in recent years, and while the area is now mature, a steady stream of developments continues. In the boom days of the late 1970s and 1980s, a typical North Sea installation was a large platform, which occasionally a new pipeline or, more commonly, a tie-in to the area`s massive export grids. These days, now that technical developments have enabled operators to justify developments of smaller, once uneconomic, discoveries, it is pointless to talk of a typical offshore development. Northwest Europe`s offshore operators have learned that it is worthwhile to rack their brains for the most economic development concepts. This creativity is reflected in recent development plans. While operators are now snatching up the small accumulations in and around the mature North Sea producing fields, they are also seeking develop frontier regions. The paper discusses development activities in UK, Ireland, Denmark and Greenland, and Norway in gas, oil, and gas condensate deposits.

  15. Mass extinctions show selective patterns in crinoid body size

    Science.gov (United States)

    Soto, A.; Tang, C.; Pelagio, M.; Heim, N. A.; Payne, J.

    2013-12-01

    There have been five major extinctions on planet Earth: the end of the Ordovician, late Devonian, late Permian, late Triassic and the late Cretaceous and through all of these, Crinoids have still managed to prosper. Our project attempts to find a correlation between these five mass extinctions and the body size of Crinoids. Past research has shown that bigger animals are more prone to extinction compared to smaller sized ones because of their complex environmental niches. We hypothesized that small-sized Crinoids would have a higher possibility of survival compared to the larger-sized Crinoids. We first graphed Crinoids' maximum body size and the five major extinctions throughout time for any visual correlation between them. We then used t-tests as our statistical analyses to find any differences between the size of survivors and. There was no mean difference between the mean size of victims and survivors with the exception of the end of the Triassic extinction. There are many possible explanations for this difference in the end of the Triassic such as 1) a rise in atmospheric CO2, 2) a combination was volcanic CO2 and catastrophic dissociation of gas hydrate, and/or 3) a cooling in temperature and oceanic changes occurred.

  16. 21 CFR 1314.150 - Order To show cause.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Order To show cause. 1314.150 Section 1314.150... CHEMICAL PRODUCTS Order to Show Cause § 1314.150 Order To show cause. (a) If, upon information gathered by... upon the regulated seller or distributor an order to show cause why the regulated seller or...

  17. 29 CFR 34.41 - Notice to Show Cause.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Notice to Show Cause. 34.41 Section 34.41 Labor Office of... Show Cause. (a) The Director may issue a Notice to Show Cause to a recipient failing to comply with the... compliance review. (b) The Notice to Show Cause shall contain: (1) A description of the violation and...

  18. "The George Lopez Show": The Same Old Hispano?

    Science.gov (United States)

    Markert, John

    2007-01-01

    "The George Lopez Show" is the first successful television show with a Latino in a leading role that features Hispanic material since Freddie Prinze's thirty-year-old sitcom, "Chico and the Man." This study seeks to assess how Latinos are presented on "The George Lopez Show." A content analysis reveals that the show perpetuates some of the…

  19. Isolation and structural characterization of the smaller-size oligosaccharides from desialylated human κ-casein. Establishment of a novel type of core for a mucin-type carbohydrate chain

    NARCIS (Netherlands)

    Vliegenthart, J.F.G.; Halbeek, H. van; Fiat, A.-M.; Jollès, P.

    1985-01-01

    Alkaline borohydride reductive cleavage (beta-elimination) of desialylated human kappa-caseinoglycopeptide resulted in the release of a series of oligosaccharides. The smaller-size compounds among them were purified to virtual homogeneity by gel filtration followed by high-performance liquid chromat

  20. Smaller Communities Program: Grant and Wheeler Counties, Oregon. Combined Economic Base Report and Applicant Potential Report; An Evaluation of the Economic and Human Resources of a Rural Oregon County.

    Science.gov (United States)

    Oregon State Dept. of Employment, Salem.

    Prepared by the Smaller Communities Services Program of the Oregon Department of Employment, this 1968 report summarizes the program findings with relation to Grant and Wheeler counties, Oregon. As stated, the overall objective of the program was promotion of the economic adjustment of specific rural, low-income areas--including the occupational…