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Sample records for gao ming wang

  1. Important contributions of M.C. Wang and C.S. Wang Chang to non-equilibrium statistical physics

    International Nuclear Information System (INIS)

    Liu Jixing

    2004-01-01

    In the middle of the 20th century two Chinese women physicists, Ming-Chen Wang and Cheng-Shu Wang Chang made great contributions to statistical physics. The famous review article 'On the theory of the Brownian motion II' by Ming-Chen Wang and G.E. Uhlenbeck published in Rev. of Mod. Phys. in 1945 provided a complete scientific classification of stochastic processes which is still adopted by the scientific community as the standard classification. The Wang-Chang-Uhlenbeck (WCU) equation proposed jointly by C.S. Wang-Chang and Uhlenbeck became the fundamental kinetic equation for the treatment of transport properties of multi-atomic gases with internal degrees of freedom in the physics literature. These important scientific contributions are analyzed and reviewed

  2. Zhu Qing Wang

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Zhu Qing Wang. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 543-548. Highly sensitive optical chemosensor for the detection of Cu using a rhodamine B spirolatam · Gen Hua Wu Dong Xiang Wang Da Yu Wu Yuan Gao Zhu Qing Wang.

  3. Tai An's Famous and Aristocratic Official Families in Korean---New Research on Wang Yiwen Family Adherent to the End of Ming Dynasty%流寓韩国的泰安名臣世家--明末遗民王以文族系新考

    Institute of Scientific and Technical Information of China (English)

    周郢

    2016-01-01

    韩国历史上著名之“九义士”,乃指明清之际随同朝鲜质子入境的九位明朝士人。其中之王以文,传系明臣王楫孙。王楫为明泰安州人,故里即今岱岳区范镇大王庄。范镇王氏所藏道光钞本《王氏族谱》中,不少内容堪与韩国史料相印证。两者在王楫及其先世的记述基本一致,而王楫之后则存在较大差异。入朝王氏系出于泰安范镇王氏家族洵无疑义,但王以文是否为王楫之孙,仍有进一步查证之余地。%The famous "nine righteous men" in Korean history was the nine scholars who had been ac-companying Korean hostage back to Korean at the end of Ming Dynasty. Wang Yiwen, the grandson of Wang Ji, the Ming minister who was from Da Wang Village of Fan County in Tai An. The book Wangs Pedigree of a Clan formed in Dao Guang of Qing Dynasty contained the same contents with Korean historical materials. Wang Ji and his ancestors' documents are generally the same, and his offspring's are different. So it is con-firmed that Wangs in Korea are from Tai An, but Wang Yiwen's origin should give further investigation.

  4. Wang Guowei's Application of Kant

    Directory of Open Access Journals (Sweden)

    JINLI HE

    2015-01-01

    Full Text Available Wang Guowei (1887-1927 was a late Qing scholar who assumed a pioneer role in introducing Western philosophy and is regarded as the founder of Chinese ideas about philosophical and literary-aesthetic modernity. His introduction and interpretation not only has been inspiring later scholars to be interested in European philosophy but also being a “showcase” of the “localness” of a cultural interpretation. This paper focuses on Kant’s influence on Wang Guowei, especially Wang’s use of Kant’s epistemological, ethical and aesthetic theories to reconstruct the important Chinese philosophical conceptions, such as, 'xing'性, 'li'理, 'ming'命, 'ya'雅 and what he called as Confucius’ 'meiyuzhuyi'美育主義(aesthetic educational-ism and aims to achieve a better grasp of the continuity and revolution that accompany the emergence of Chinese modernity as well as a better understanding of comparative culture (philosophy in its “primitive” phase.

  5. [Some problems concerning the population thought in the Ming and Quing dynasties].

    Science.gov (United States)

    Zhang, M R

    1982-09-29

    After the middle of the Ming dynasty, the Chinese feudal system began to show some influence of capitalism in its production models. Changes began to take place in its political and economic systems. In 1723, a new method of household taxation was adopted to replace the traditional taxation system, which had been based upon the population of each household. Under the new system, taxation was based upon the size of the land each household owned. As a result of this change, the population showed rapid growth. Intellectuals began to form the concept of curbing excessive population growth. They also began to pay attention to the problems of adequate material supplies, overpopulation, and possible solutions. Chinese intellectuals and scholars of the late Ming and Qing dynasties, including Xu Guangqi, Hong Liangji, Wang Shifeng, and Xue Fucheng realized the serious nature of population growth. In fact, the population figure doubledever 30 years on a regular basis. The rapid population growth caused a decline in the living standard, higher prices for consumer goods, unemployment, a decline in the population quality, and social disorders. Hong Liangji suggested that natural disasters such as floods and droughts could help reduce the population, and that improvement in agriculture, emigration, and tax reductions could promote production. Wang Shifeng was in favor of using severe laws and restrictions on marriage to control population. Xue Fucheng proposed the idea of imitating Western countries to develop capitalism and industries and increase employment opportunities to reduce the pressure of the rapid population growth.

  6. WAN-MING LIU

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. WAN-MING LIU. Articles written in Sadhana. Volume 41 Issue 7 July 2016 pp 713-719. Integrated fleet assignment and aircraft routing based on delay propagation · WAN-MING LIU XING-HUI ZHU YAN-LONG QI · More Details Abstract Fulltext PDF. Airlines' expensive resources, especially aircraft ...

  7. The Tūqmāq and the Ming China: The Tūqmāq and the Chinese Relations during the Ming Period (1394–1456)

    OpenAIRE

    Kenzheakhmet N.

    2017-01-01

    Objective: Little is known about diplomatic relations between the Jūchīd Ulūs and Ming China (1368–1644), even though some evidence of early tributary trade relations exists. The first extant Chinese account about the country of Salai (Saray) dates to around 1394, when accounts of diplomatic exchange between the Ming court and the Jūchīd Ulūs began to appear in the Ming shilu (The Veritable Records of the Ming). Research materials: This article analyzes the Ming shilu in order to understan...

  8. ming-fa hsieh

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. MING-FA HSIEH. Articles written in Bulletin of Materials Science. Volume 40 Issue 6 October 2017 pp 1179-1187. Preparation, characterization of chitosan/bamboo charcoal/poly(methacrylate) composite beads · DOROTHY CAMINOS-PERUELO WEI-CHIEH WANG ...

  9. The "Da Ming Hunyi Tu": Repurposing a Ming Map in Sino-African Diplomacy

    Directory of Open Access Journals (Sweden)

    Alexander Akin

    2016-12-01

    Full Text Available In 2002, an exhibition at South Africa’s parliament included a reproduction of the Da Ming Hunyi Tu (Amalgamated map of the Great Ming, citing it as the earliest world map to depict the entire African continent. As part of its broader efforts to shape a narrative of long-standing and peaceful international relations with Africa, the People’s Republic of China formally presented a replica of this map as a gift to the South African government in conjunction with the exhibition. In official statements and popular media coverage alike, the map was described as evidence of a distinctly Chinese approach to global relations, based on benevolence and mutual respect. In particular, the map was ahistorically intertwined with the legacy of Zheng He’s diplomatic expeditions, which reached the East African coast in the early 1400s. To the cartographic historian, however, the depiction of Africa in the Da Ming Hunyi Tu is clearly derived from non-Chinese sources that predate Zheng He’s expeditions. This article examines the ways in which the map has been divorced from its original context to suit modern needs, exemplifying the deployment of cartography to deflect anxieties about the nature of Chinese economic influence in South Africa.

  10. A STUDY ON PRINTMAKING IN MING AND QING DYNSTIES IN CHINA

    Institute of Scientific and Technical Information of China (English)

    赵丽媛

    2017-01-01

    Ming and Qing Dynasties printmaking have a unique form of expression, color and content. This article focuses on the artistic characteristics of the woodcut New Year paintings in the Ming and Qing Dynasties. Ming and Qing printmaking simple, natural, bold. Ming and Qing Dynasties folk woodcut New Year paintings of the composition of the pursuit of integrity, rich, sym-metrical, so that the composition of the screen harmony and unity. It is worth learning for our absorption.

  11. The Tūqmāq and the Ming China: The Tūqmāq and the Chinese Relations during the Ming Period (1394–1456

    Directory of Open Access Journals (Sweden)

    Kenzheakhmet N.

    2017-12-01

    Full Text Available Objective: Little is known about diplomatic relations between the Jūchīd Ulūs and Ming China (1368–1644, even though some evidence of early tributary trade relations exists. The first extant Chinese account about the country of Salai (Saray dates to around 1394, when accounts of diplomatic exchange between the Ming court and the Jūchīd Ulūs began to appear in the Ming shilu (The Veritable Records of the Ming. Research materials: This article analyzes the Ming shilu in order to understand the character of Chinese knowledge about the Jūchīd Ulūs during their years of contact between 1394 and 1456. Additional sources like geographic accounts and maps help define the extent of Chinese knowledge about the khanate, clarify the kinds of information that the Chinese sought and the reasons why, and measure the influence of cross-cultural contact on Ming Chinese understanding of the Jūchīd Ulūs. Results and novelty of the research: The Ming shilu suggests that at least by the end of the fourteenth and the early years of the fifteenth century, Salai (Saray became an integral, and possibly the most important, element in the name that the Ming court used for the country of the Jūchīd Ulūs. The Persian and Mongol historians used the term Tūqmāq and Togmog to refer to the Jūchīd Ulūs, while Ming Chinese historians used the term Tuohema to refer to the Jūchīd Ulūs or the whole Dasht-i Qipchāq, in post-Mongol Central Eurasia. The diplomatic contact between Ming China and the Tuohuma occurred through the Chinese system of tribute trade during the mid-fifteenth century. Under the reign of Yongle (1402–1424, Zhengtong (1435–1449, and Jingtai (1449–1457, the foundations for a flourishing relationship between Ming China and the Jūchīd Ulūs were established. At that time, the Chinese knew the Jūchīd Ulūs by the name Salai (Saray and Tuohuma (Tūqmāq. Despite the political turmoil that erupted after the fall of the Jūchīd Ul

  12. Eyebrow Shapes of Chinese Empresses of the Ming and Qing Dynasties.

    Science.gov (United States)

    Hwang, Kun; Yoo, Seong Kyung

    2018-03-14

    The aim of this study was to analyze eyebrow shapes in portraits of Chinese empresses of Ming and Qing dynasties.The frontal portraits of 20 Ming empresses and 24 of Qing in which the eye and eyebrows were identifiable were measured and analyzed. The arch shape did not differ significantly (P > 0.05) between Ming and Qing. The head-up type (66.6%) was significantly more common (P Qing empresses were classified as 5 arch types: L (Lamas), A (Anastasia), H (Hwang), M (Empress Ma), and D (Empress Du). In Ming, type-H (45.0%) was the most frequent, followed by type-D (25.0%). In Qing, type-L (45.8%) was the most frequent, followed by type-H (16.7%) and type-D (16.7%). The relative eyebrow width (REW) of Ming and Qing was 1.59 ± 0.28. The REW of Qing (1.63 ± 0.30) and Ming (1.55 ± 0.26) did not differ significantly. The relative medial height (RMH, 1.05 ± 0.20) and relative lateral height (RLH; 1.05 ± 0.21) were the same, and greater than the relative mid-pupillary height (RPH; 0.84 ± 0.19; P Qing (1.02 ± 0.16) did not differ significantly. The RLH likewise did not differ significantly between Ming (1.01 ± 0.21) and Qing (1.08 ± 0.22). However, the RPH of Ming (0.91 ± 0.21) was significantly (P = 0.042) greater than Qing (0.79 ± 0.17). The relative brow thickness (RBT) of Qing (0.13 ± 0.06) was significantly (p = 0.033) greater than Ming (0.17 ± 0.06). The RBT of Ming and Qing was 0.15 ± 0.06 and increased with time (P = 0.023).The results of this study may be useful for brow lift or the tattooing.

  13. A simple extension of “An alternative approach to sea surface aerodynamic roughness” by Zhiqiu Gao, Qing Wang, and Shouping Wang

    Science.gov (United States)

    Gao, Zhiqiu; Wang, Linlin; Bi, Xueyan; Song, Qingtao; Gao, Yuchao

    2012-08-01

    Based on the data previously collected during the Humidity Exchange over the Sea Main Experiment (HEXMAX), the methods used to parameterize aerodynamic roughness (z0), friction velocity (u*), and the neutral drag coefficient (CDN) under moderate wind speed conditions originally proposed by Gao et al. (2006) were extended by using the nondimensional significant wave height (gHs/u*2 or gHs/U10N2) instead of wave age (cp/u* or cp/U10N), where g is the acceleration of gravity, Hs is the significant wave height, U10Nis the horizontal wind speed at 10-m height under the neutral atmospheric condition, andcp is the phase velocity of the peak wave spectrum. The results show (1) u* = 0.024U10N(gHs/U10N2)-1/4, (2) z0 = 10 × exp[-4.797(gHs/u*2)1/6] or z0 = 10 × exp[-16.613(gHs/U10N2)1/4], and (3) CDN = 0.007(gHs/u*2)-1/3 or CDN = 5.76 × 10-4(gHs/U10N2)-1/2. The present parameterization schemes were experimentally tested.

  14. Qing Wang

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Qing Wang. Articles written in Bulletin of Materials Science. Volume 29 Issue 3 June 2006 pp 313-316 Composites. Anisotropic properties of aligned SWNT modified poly (methyl methacrylate) nanocomposites · Weixue Li Qing Wang Jianfeng Dai · More Details Abstract Fulltext ...

  15. A reviewof the pharmacologicalmechanism of traditional Chinese ...

    African Journals Online (AJOL)

    A reviewof the pharmacologicalmechanism of traditional Chinese medicine in the intervention of coronary heart disease and stroke. W Zhang, K Gao, K Gao, J Liu, J Liu, H Zhao, H Zhao, J Wang, J Wang, Y Li, Y Li, G Murtaza, G Murtaza, J Chen, J Chen, W Wang, W Wang ...

  16. GAO

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This paper reports that Venezuela's 1991 foreign investment reforms did little to encourage U.S. oil companies to invest there despite the overall investment attractiveness of the country's oil sector, says the U.S. General Accounting Office. In a report to Congress, GAO noted Venezuela's oil production peaked in 1970, declined through 1985, and since then has increased by about 21% through 1990. The primary factors affecting continued increases in production through 1996 include Petroleos de Venezuela SA's ability to encourage investment capital, the cost of producing and refining heavy and extra heavy crude oil., and the level of production quotas imposed by the Organization of Petroleum Exporting Countries, of which Venezuela is a member. GAO noted Venezuela implemented policy reforms in 1991 to encourage some foreign and private investment petroleum related ventures. However, these reforms have not yet succeeded in attracting U.S. investment in oil exploration, production, or refining in Venezuela

  17. A GAO hiding among the PAO

    DEFF Research Database (Denmark)

    McIlroy, Simon Jon; Albertsen, Mads; Stokholm-Bjerregaard, Mikkel

    “Candidatus Accumulibacter phosphatis” (Accumulibacter) and the model GAO being the gammaproteobacterial “Candidatus Competibacter phosphatis” (see Oehmen et al., 2007). Here, we report the discovery of a GAO from the genus Propionivibrio, which is closely related to Accumulibacter. Propionivibrio is often...

  18. Mr.Seah Moon Ming Leadership & Management

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Life and Work Philosophy Seah Moon Ming considers life a continuous journey of learning,adaptation and attainment of goals.He believes that as long as there are changes,you will need to learn - to learn to adapt and to play a useful role in a dynamic and ever-changing world.

  19. Effect of Qi Ming Granule on the choroidal circulation in diabetic patients

    Directory of Open Access Journals (Sweden)

    Ke-Jun Li

    2016-03-01

    Full Text Available AIM:To investigate the effect of a Chinese medicine(Qi Ming granuleon the retinal and choroidal circulation in diabetes patients. METHODS: According to the results of fundus fluorescein angiography(FFA, all the 45 diabetes patients were divided into no diabetic retinopathy(NDRgroup and nonproliferative diabetic retinopathy(NPDRgroup. All subjects were examined by FFA and indocyanine green angiography(ICGAat the same time. After taken Qi Ming granule for 3mo, all subjects were examined by the same method. FFA and ICGA were used to evaluate the retinal and choroidal circulation and their features. The key points were filling time for the retinal and choroidal circulation before and after treatments. The accuracy data was used to evaluate the effect.RESULTS: After taken Qi Ming granule for 3mo, there were significant decrease of the retina and the choroid filling time in NDR and NPDR groups. The occurrence rate of various abnormal angiographic features were significantly decreased. CONCLUSION: Qi Ming granule can accelerate the blood flow of retina and choroid, improve the blood circulation in diabetes patients, and delay the occurrence and development of diabetic retinopathy.

  20. [Chemical composition and chromaticity characteristic of Jilan glaze of Ming and Qing official kilns].

    Science.gov (United States)

    Wu, Jun-ming; Zhang, Mao-lin; Li, Qi-jiang; Wu, Juan; Quan, Kui-shan; Cao, Jian-wen

    2012-08-01

    Color glazes of Ming and Qing official kilns are excellent representatives of the famous ancient Chinese porcelains. The study of official ware with Jilan glaze has been an important topic. But it made slow progress due to the rarity of samples with strict production management and using system. The recipes, chemical composition and chromaticity characteristic of the Jilan samples excavated from official kilns in the Ming and Qing dynasties were first discussed by systematical testing with the energy dispersive X-ray fluorescence (EDXRF) and color difference meter. The results showed that the porcelain stone content in Jilan bodies of official kiln in the Ming dynasty is higher than the samples of the Qing dynasty. The manganese content in Jilan glazes of the Ming dynasty is higher than that in the Qing dynasty, while the glaze ash addition and the lightness value in the glaze are opposite.

  1. 4 CFR 25.3 - Admission to the GAO building.

    Science.gov (United States)

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Admission to the GAO building. 25.3 Section 25.3 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES CONDUCT IN THE GOVERNMENT ACCOUNTABILITY OFFICE BUILDING AND ON ITS GROUNDS § 25.3 Admission to the GAO building. A person may be admitted to the GAO Building...

  2. 78 FR 2478 - Culturally Significant Objects Imported for Exhibition Determinations: “Ming Masterpieces From...

    Science.gov (United States)

    2013-01-11

    ... ``Ming Masterpieces from the Shanghai Museum,'' imported from abroad for temporary exhibition within the... Determinations: ``Ming Masterpieces From the Shanghai Museum'' SUMMARY: Notice is hereby given of the following... at the Los Angeles County Museum of Art, Los Angeles, CA, from on or about March 3, 2013, until on or...

  3. [Textual research on circulation of the Ming edition of Li Heng's Xiu zhen fang (Pocket Formulary)].

    Science.gov (United States)

    Yang, Jinping; Liu, Peng; Lu, Mingjing; Lu, Xing; Li, Shaolin; Jin, Xiumei

    2015-03-01

    Xiu zhen fang (Pocket Formulary) is a recipe book of the Ming Dynasty, inspired and managed by Zhu Su, compiled by Li Heng of liangyisuo (good physician house) in Zhou wangfu (Zhou's royal palace). The book was compiled and published twice during the reigns of the Hongwu and Yongle Emperors of the Ming Dynasty. Because of its high practicability, there were some editions in circulation, and the book was published several times only in the Ming Dynasty. At present, the earliest extanteditionwas the little character version of Yongle, and the version in the 4(th) year of Zhengde Emperor of the Ming Dynasty was a reprinting edition based on the Yongle edition, sharingthe same edition system. Most of the editions appeared after the reign of Zhengtong Emperor of the Ming Dynasty, titled by "kui ben (head version)" and "da quan (complete edition)" were the editionspublished in the local bookshops, which had rather distinct differences from the Yongle edition system not only in the its format but also in its contents.

  4. Population growth, deforestation, and fuel substitution in Ming Beijing (Ecology, China)

    Energy Technology Data Exchange (ETDEWEB)

    Chiu, C.L. [Academy of Sinica, Taipei (Taiwan)

    2003-03-01

    This article investigates why people of Beijing started to burn coal instead of logs after the middle Ming Dynasty. The records of the city's population, illegal logging and the government's fuel policy showed the Beijing's population boom, which resulted in a stronger demand of cooking fuel and construction materials, had led to illegal logging. In the early 16th century, there were hardly any trees on the Yan Mountain north of Beijing. On the other hand, to provide huge amounts of fuel for the palace and offices, the government set up a charcoal works on the northern Tiahang Mountain, which is southwest of Beijing. In 1442, 57,000 tons firewood and charcoal were burned for official purposes. Even though the quantity declined later, it still consumed 30,000 tons firewood and charcoal a year during the middle of the 16th century. After the middle of the 15th century, forests around Beijing disappeared due to extensive logging. The prices of logs also went up. Therefore people started to use easily available coal. Since the late 15th century, written accounts of coal mining in the mountain west of Beijing were increasing. In the early Ming, Beijing's households burned logs. Since then, more and more adopted coal burning especially during the late Ming. The city became so dependent on West Mountain's coal mine that any northern invasion that crossed the Great Wall would cause a coal supply problem. Fuel substitution in Beijing throughout the Ming Dynasty was a good example of environmental change caused by urban development. After the loss of forests and the mass consumption of coal, the city's environment also changed. Ever since the late Ming, coal-burning-caused problems such as earth dumping and air pollution were worsening. Evidently, the city of Beijing was suffering from the decay of its environment since the late 16th century.

  5. Towards a Collective Intelligence: Transmediality and the Wu Ming Project

    Directory of Open Access Journals (Sweden)

    Melina Anne Masterson

    2014-11-01

    Full Text Available Dagli albori della Seconda Repubblica in Italia,  le strategie di dominio sui mass media dell’ex premier Silvio Berlusconi hanno avuto un effetto considerevole sull’immaginario culturale italiano. In un approccio multisensoriale e multimediale alla scrittura, il collettivo Wu Ming mette in questione i paradigmi culturali che negli ultimi venti anni sono diventati egemonici. L’esperienza di un romanzo dei Wu Ming va ben oltre la parola stampata poiché cerca di stimolare tutti i cinque sensi per arricchire il modo in cui il lettore vive quello che c’è sulla pagina, dimostrando esempi chiari della «convergence culture» coniata da Henry Jenkins. Questo saggio esamina l’interazione tra parola e immagine messa in atto dal collettivo tramite il sito Pinterest e illustra come questo aspetto del loro progetto rappresenti un microcosmo di un approccio complessivo alla creazione estetica e alla pratica culturale. Inoltre, questo saggio descrive in che modo il processo collettivo di consumo portato avanti dai Wu Ming contribuisca alla formazione delle «communities of sentiment» di Arjun Appadurai e alla «intelligenza collettiva» di Jenkins. Queste sono formazioni che rivitalizzano il concetto di cultura popolare per la nostra epoca digitale e offrono un’alternativa ad un immaginario culturale italiano sovra-determinato dalle pratiche del Berlusconismo.

  6. A Response to Stewart, McElwee, and Ming

    Science.gov (United States)

    Martin, Garry L.; Yu, C. T.

    2010-01-01

    In a recent article published in "The Behavior Analyst," Stewart, McElwee, and Ming (2010) suggested that "scientific experts in scientific contexts" should use more "technically accurate and precise labeling" when describing the Assessment of Basic Learning Abilities (ABLA) in published articles. They concluded by stating, "We believe that…

  7. Jun Wang

    Indian Academy of Sciences (India)

    0.32O2 solid solution on depositing -alumina washcoat on .... Volume 38 Issue 5 September 2015 pp 1435-1438. High-performance aqueous rechargeable batteries based on zinc anode and NiCo2O4 cathode · Jun Wang Zhijun Jia Songbo Li ...

  8. GAO Strategic Plan 2007-2012

    National Research Council Canada - National Science Library

    2007-01-01

    In keeping with GAO's commitment to update its strategic plan at least once every 3 years consistent with the Government Performance and Results Act this strategic plan describes our proposed goals...

  9. Designing Evaluations. 2012 Revision. Applied Research and Methods. GAO-12-208G

    Science.gov (United States)

    US Government Accountability Office, 2012

    2012-01-01

    GAO assists congressional decision makers in their deliberations by furnishing them with analytical information on issues and options. Many diverse methodologies are needed to develop sound and timely answers to the questions the Congress asks. To provide GAO evaluators with basic information about the more commonly used methodologies, GAO's…

  10. Study on elemental features of Longquan celadon at Fengdongyan kiln site in Yuan and Ming Dynasties by EDXRF

    Energy Technology Data Exchange (ETDEWEB)

    Li, L. [Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Lu, Beijing 100049 (China); Feng, S.L., E-mail: fengsl@ihep.ac.cn [Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Lu, Beijing 100049 (China); Feng, X.Q.; Xu, Q.; Yan, L.T.; Ma, B.; Liu, L. [Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Lu, Beijing 100049 (China)

    2012-12-01

    The energy dispersive X-ray fluorescence (EDXRF) is used to determine the chemical compositions of Longquan celadon body and glaze at Fengdongyan kiln in Yuan and Ming Dynasties. In order to analyze the elemental features in different cultural periods, 196 typical Longquan celadon shards are selected including the Early Yuan (EY), the Middle and Late Yuan (MLY), the Early Ming (EM) and the Middle Ming (MM) periods. The results indicate that the contents of K{sub 2}O, CaO, TiO{sub 2} and Fe{sub 2}O{sub 3} for celadon body and glaze are various in different cultural periods. The b values b=RO/(RO+R{sub 2}O), RO represents for alkali-earth metal elements and R{sub 2}O stands for alkali metal elements) show that the glazes of Longquan celadon in Yuan and Ming Dynasties belong to the category of calcium-alkali glaze. The principal component analysis (PCA) exhibits that the raw materials used for body and glaze in four periods have the inheritance relation. The only difference is that the raw materials for glaze in MM period were similar to those in EM period. The producing and firing technology of Longquan celadon had reached a higher level in the Early Ming Dynasty.

  11. [Professor GAO Yuchun's experience of acupuncture for headache].

    Science.gov (United States)

    Cui, Linhua; Xing, Xiao; Xue, Weihua; Wang, Yanjun; Xu, Cejun; Xuc, Jun; Gao, Yuchun; Kang, Suobin

    2015-12-01

    As one of the important founders of GAO's acupuncture academic school in YanZhao area, Professor GAO Yuchun 's experience of acupuncture for headache is summarized in this paper. In the opinion of Professor GAO, the treatment of headache should focus on eliminating evil and relieving pain, and the syndrome differentiation should be based on meridian differentiation, especially on three yang meridians of foot as well as liver meridian and kidney meridian. In the acupoint prescription, attention should be placed on strengthening the spleen and stomach. The midnight-midday ebb flow acupuncture is advocated. The combination between acupuncture order and movement of qi is emphasized. In the manipulation, the role of pressing hand, the stimulation during reinforcing and reducing methods, and needle-retention time are important. The breathing reinforcing and reducing method of acupuncture are also advocated.

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Hsinyu Lee. Articles written in Journal of Biosciences. Volume 37 Issue 1 March 2012 pp 157-165 Review. Autophagy: A double-edged sword in Alzheimer's disease · Ying-Tsen Tung Bo-Jeng Wang Ming-Kuan Hu Wen-Ming Hsu Hsinyu Lee Wei-Pang Huang Yung-Feng Liao.

  13. Wang Tiles in Computer Graphics

    CERN Document Server

    Lagae, Ares

    2009-01-01

    Many complex signals in computer graphics, such as point distributions and textures, cannot be efficiently synthesized and stored. This book presents tile-based methods based on Wang tiles and corner tiles to solve both these problems. Instead of synthesizing a complex signal when needed, the signal is synthesized beforehand over a small set of Wang tiles or corner tiles. Arbitrary large amounts of that signal can then efficiently be generated when needed by generating a stochastic tiling, and storing only a small set of tiles reduces storage requirements. A tile-based method for generating a

  14. Spatial chaos of Wang tiles with two symbols

    Science.gov (United States)

    Chen, Jin-Yu; Chen, Yu-Jie; Hu, Wen-Guei; Lin, Song-Sun

    2016-02-01

    This investigation completely classifies the spatial chaos problem in plane edge coloring (Wang tiles) with two symbols. For a set of Wang tiles B , spatial chaos occurs when the spatial entropy h ( B ) is positive. B is called a minimal cycle generator if P ( B ) ≠ 0̸ and P ( B ' ) = 0̸ whenever B ' ⫋ B , where P ( B ) is the set of all periodic patterns on ℤ2 generated by B . Given a set of Wang tiles B , write B = C 1 ∪ C 2 ∪ ⋯ ∪ C k ∪ N , where Cj, 1 ≤ j ≤ k, are minimal cycle generators and B contains no minimal cycle generator except those contained in C1∪C2∪⋯∪Ck. Then, the positivity of spatial entropy h ( B ) is completely determined by C1∪C2∪⋯∪Ck. Furthermore, there are 39 equivalence classes of marginal positive-entropy sets of Wang tiles and 18 equivalence classes of saturated zero-entropy sets of Wang tiles. For a set of Wang tiles B , h ( B ) is positive if and only if B contains a MPE set, and h ( B ) is zero if and only if B is a subset of a SZE set.

  15. Study on the property of the production for Fengdongyan kiln in Early Ming dynasty by INAA and EDXRF

    International Nuclear Information System (INIS)

    Li, L.; Huang, Y.; Sun, H.Y.; Yan, L.T.; Feng, S.L.; Xu, Q.; Feng, X.Q.

    2016-01-01

    A lot of official wares carved “Guan” or the dragon patterns were excavated on the strata of Ming dynasty of the Fengdongyan kiln site at Dayao County. The imperial porcelain was fired in Hongwu and Yongle eras. However, the emergence of this imperial porcelain has triggered academic debate about the property of Fengdongyan kiln in the Early Ming dynasty. Based on the differences of the official kiln management, some scholars have determined that the property of the production for this kiln was the civilian kiln. According to the historical textural records and typology, others preliminary confirmed that Fengdongyan kiln was the official kiln. In this paper, the elemental compositions of body and glaze in imperial and civilian porcelain are study by INAA and EDXRF for determining the property of the production for this kiln in Early Ming dynasty. After the processing of experimental data by geochemical analysis and principal component analysis, the result show that the raw materials for making body and glaze in imperial porcelain are similar with those of the civilian porcelain and the degrees of elutriation for body can be slightly different in HW-M period of Ming dynasty. The analytical results support the view that the Fengdongyan kiln is civilian not official.

  16. Study on the property of the production for Fengdongyan kiln in Early Ming dynasty by INAA and EDXRF

    Energy Technology Data Exchange (ETDEWEB)

    Li, L. [Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Lu, Beijing 100049 (China); Huang, Y.; Sun, H.Y. [Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Lu, Beijing 100049 (China); University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049 (China); Yan, L.T.; Feng, S.L.; Xu, Q. [Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Lu, Beijing 100049 (China); Feng, X.Q., E-mail: fengxq@ihep.ac.cn [Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Lu, Beijing 100049 (China)

    2016-08-15

    A lot of official wares carved “Guan” or the dragon patterns were excavated on the strata of Ming dynasty of the Fengdongyan kiln site at Dayao County. The imperial porcelain was fired in Hongwu and Yongle eras. However, the emergence of this imperial porcelain has triggered academic debate about the property of Fengdongyan kiln in the Early Ming dynasty. Based on the differences of the official kiln management, some scholars have determined that the property of the production for this kiln was the civilian kiln. According to the historical textural records and typology, others preliminary confirmed that Fengdongyan kiln was the official kiln. In this paper, the elemental compositions of body and glaze in imperial and civilian porcelain are study by INAA and EDXRF for determining the property of the production for this kiln in Early Ming dynasty. After the processing of experimental data by geochemical analysis and principal component analysis, the result show that the raw materials for making body and glaze in imperial porcelain are similar with those of the civilian porcelain and the degrees of elutriation for body can be slightly different in HW-M period of Ming dynasty. The analytical results support the view that the Fengdongyan kiln is civilian not official.

  17. [Effective acupoints for bulbar paralysis by professor GAO Weibin].

    Science.gov (United States)

    Kang, Lianru; Zheng, Shuang

    2016-04-01

    Professor GAO Weibin academically advocates, based on basic theory of TCM and theories of different schools, modern science technology should be used for the methods and principles of acupuncture and Chinese medicine for neuropathy, so as to explore and summarize the rules, characteristics and advantages of TCM for nervous system disease, especially bulbar paralysis. During the treatment of bulbar paralysis, professor GAO creatively proposes the effective acupuncture points such as Gongxue, Tunyan-1, Tunyan-2, Fayin, Tiyan and Zhifanliu from the aspects of neuroanatomy, and analyzes their anatomical structure and action mechanism.

  18. [Analysis of Xin'an imperial medical officials in the Ming and Qing Dynasties].

    Science.gov (United States)

    Wan, S M; Liu, B S; Lu, X

    2017-01-28

    Xin'an imperial medical officials of the Ming and Qing Dynasties was a special group of Xin'an doctors. It had exerted a positive and active impact on the development of traditional Chinese medicine. Rooted in the Xin'an region, with higher literacy and noble medical ethics and medical knowhow, through the imperial enlistment, examination, and other ways to enter the palace as imperial medical officials. During their tenure, they wrote books and communicated and merged with the folk medicine actively. After retiring, they were still involved actively in folk medicine activities, thus promoting and influencing the development of local medicine. The formation of Xin'an community of imperial medical officials in the Ming and Qing Dynasties was closely related to the prosperity of regional culture and commerce, and the development of medicine in Xin'an region.

  19. The Rubber Band Revisited: Wang-Landau Simulation

    OpenAIRE

    Ferreira, Lucas S.; Caparica, Alvaro A.; Neto, Minos A.; Galiceanu, Mircea D.

    2012-01-01

    In this work we apply Wang-Landau simulations to a simple model which has exact solutions both in the microcanonical and canonical formalisms. The simulations were carried out by using an updated version of the Wang-Landau sampling. We consider a homopolymer chain consisting of $N$ monomers units which may assume any configuration on the two-dimensional lattice. By imposing constraints to the moves of the polymers we obtain three different models. Our results show that updating the density of...

  20. The Images of Jesus in the Emergence of Christian Spirituality in Ming and Qing China

    Directory of Open Access Journals (Sweden)

    Xiaobai Chu

    2016-03-01

    Full Text Available Images of Jesus Christ played an important role in the emergence of Christian spirituality in Ming and Qing China. Of the great many images that we know from this period, this paper introduces five of them: Jesus as infant, criminal, gate, brother, and pig. The paper unfolds the historical, anthropological, and theological layers of these images to reveal the original tension between Christian spirituality and Chinese culture. The central thesis of the paper therefore is that this tension is reflected in the images of Jesus Christ and, moreover, that analyzing this tension allows us to achieve a more profound understanding of the emergence of Christian spirituality in Ming, Qing, and perhaps even today’s China.

  1. Growth, ion content and photosynthetic responses of two Elytrigia ...

    African Journals Online (AJOL)

    Jane

    2011-07-25

    Jul 25, 2011 ... Wang Zan, Zhang Geng, Wang Xue-min and Gao Hong-wen*. Institute of .... Dried leaf samples were ground to a fine powder and approximately. 0.1 g was .... structure and negative feedback by reduced sink activity. (Iyengar ...

  2. Status of GAO Recommendations to the Department of Defense (Fiscal Years 2001-2007)

    Science.gov (United States)

    2008-12-11

    Name-Brand, Fast - Food Restaurants 5 GAO-01-943 Defense Manufacturing Technology Program: More Joint Projects and Tracking of Results Could...Oversight of Contractors under Foreign Influence Is Sufficient 6 2 GAO-05-456 Interagency Contracting: Franchise Funds Provide Convenience, but Value to

  3. [Professor GAO Yuchun's experience on "sequential acupuncture leads to smooth movement of qi"].

    Science.gov (United States)

    Wang, Yanjun; Xing, Xiao; Cui, Linhua

    2016-01-01

    Professor GAO Yuchun is considered as the key successor of GAO's academic school of acupuncture and moxibustion in Yanzhao region. Professor GAO's clinical experience of, "sequential acupuncture" is introduced in details in this article. In Professor GAO's opinions, appropriate acupuncture sequence is the key to satisfactory clinical effects during treatment. Based on different acupoints, sequential acupuncture can achieve the aim of qi following needles and needles leading qi; based on different symptoms, sequential acupuncture can regulate qi movement; based on different body positions, sequential acupuncture can harmonize qi-blood and reinforcing deficiency and reducing excess. In all, according to the differences of disease condition and constitution, based on the accurate acupoint selection and appropriate manipulation, it is essential to capture the nature of diseases and make the order of acupuncture, which can achieve the aim of regulating qi movement and reinforcing deficiency and reducing excess.

  4. Highlights of GAO’s Corporate Governance, Transparency and Accountability Forum

    Science.gov (United States)

    2002-03-01

    the current accounting and reporting model does not adequately address (e.g., special purpose entities, uncovered arbitrage positions)? • Is there...TRANSPARENCY AND ACCOUNTABILITY FORUM a GAO-02-494SP Report Documentation Page Report Date 00MAR2002 Report Type N/A Dates Covered (from...its oversight in connection with these matters. In particular, the Congress and GAO are interested in changes that could serve to reduce the

  5. [The research on the edition of Daquanbencao (Complete Collection of Materia Medica)].

    Science.gov (United States)

    Li, Jian; Zhang, Wei; Zhang, Rui-xian

    2009-07-01

    Zhengleibencao (Classified Materia Medica) had been formed into several kinds of edition systems during its dissemination, among which there was the edition system of Daquanbencao (Complete Collection of Materia Medica). Daquanbencao was originally carved in the Jin dynasty, thereafter it was re-carved in the Yuan, Ming and Qing dynasties so as to form a series of editions such as the edition of Zhenyou in the second year of the Jin dynasty; the edition of the Zongwenshuyuan college in Dade renyan year of the Yuan dynasty; the WANG Qiu's carved edition of Shangyitang hall in the Ming dynasty; the carved edition of Jishanshuyuan, the Jishang mountain college in the Ming dynasty, the reprinted edition of PENG Duan-wu in the Ming dynasty, the supplementary edition of YANG Bi-da in the Qing dynasty;, and the carved edition of KE Feng-shi in the Qing dynasty. Among all the editions, Chongkanjingshizhengleidaquanbencao (Reprinted Classified Daquan Materia Medica from Historical Classics) was the representative one. As a representative of the above editions, the carved edition of WANG took the edition of the Zongwenshuyuan college of the Yuan dynasty as the original edition, but the images picture of materia medica adopted from the edition of Zhenghebencao (Materia Medica of the Zhenghe era).

  6. IEOH MING PEI: UNA IDEA, TRES VARIACIONES / Ieoh Ming Pei: one idea, three variations

    Directory of Open Access Journals (Sweden)

    Alberto Donaire Rodríguez

    2010-05-01

    Full Text Available RESUMENEl texto siguiente es un resumen de mi lección de despedida, el 18 de noviembre de 2006, al jubilarme en la Escuela de Arquitectura de Sevilla. Como no se grabó y nunca llevo escritas mis clases, ésta es una reconstrucción basada en mi guión y en las notas tomadas por algunos asistentes, a los que agradezco su interés. Por vez primera se celebraba en la Escuela un acto de esta naturaleza, por iniciativa del entonces Director, Jaime Navarro Casas. A él agradezco su presencia y sus palabras, e igualmente a Juan Luis Trillo de Leyva, que hizo una especie de recorrido sentimental de mi paso por la Escuela, que escuché con emoción. En el mismo curso dieron luego su lección de despedida dos profesores que han dejado en nosotros honda huella, Rafael Manzano y José Luis Manzanares. Estos actos son un bello colofón de una carrera académica. La clase fue una reflexión sobre la arquitectura, al hilo del comentario de tres obras del arquitecto Ieoh Ming Pei en tres ciudades diferentes: las ampliaciones de la National Gallery de Washington, del Museo del Louvre de París y del Deutsches Historisches Museum de Berlín. SUMMARYThe following text is a summary of my valedictory lecture, on 18 November 2006, on my retirement from the School of Architecture of Seville. As it was not recorded, and my never having written up my classes, this is a reconstruction based on my outline and the notes taken by some of those present, whom I thank for their interest. This was the first time an act of this nature was held in the School, on the initiative of the then Director, Jaime Navarro Casas. I thank him for his presence and his words, and also Juan Luis Trillo de Leyva, who made a sort of sentimental journey of my time at the School, to which I listened with emotion. Later, valedictory lectures were given by two teachers who have left a profound imprint on us, Rafael Manzano and José Luis Manzanares. These acts are a beautiful conclusion to an

  7. Effect of domains configuration on crystal structure in ferroelectric ...

    Indian Academy of Sciences (India)

    2017-09-09

    Sep 9, 2017 ... It is well known that domains and crystal structure control the physical properties of ferroelectrics. ... The as-prepared ceramics were crushed to fine pow- ders. ..... [1] Gao J, Xue D, Wang Y, Wang D, Zhang L, Wu H et al 2011.

  8. Editorial: Which Wei Wang?

    International Nuclear Information System (INIS)

    Sprouse, Gene D.

    2007-01-01

    The APS journals receive manuscripts from scientists all over the world. For authors whose names cannot be expressed in Latin characters, their names in the byline must be transliterated, a process that is not necessarily bidirectionally unique. For example, the eight Chinese names all transliterate as Wei Wang. To remove some of the ambiguity arising from this unfortunate degeneracy of names, APS will allow some authors the option to include their names in their own language in parentheses after the transliterated name, such as Wei Wang. The option to present names in the article byline in this manner is an experiment initially offered to Chinese, Japanese, and Korean authors, whose names can be expressed in Unicode characters. An example of a Japanese name is Tadanori Minamisono and a Korean name is Chang Kee Jung. In the English text the given name precedes the family name, while the reverse is true for the characters. As we gain experience, we may be able to broaden this offer to other languages. Authors who wish to try this option will need to prepare their manuscripts by following the special instructions at http://authors.aps.org/names.html

  9. Background Materials on Ching Ming Festival [And] Winter Festival [And] Dragon Boat Festival.

    Science.gov (United States)

    Lew, Helene

    This publication contains three background papers on Chinese festivals which are still celebrated by Chinese Americans. The first festival discussed--Ching Ming--is a celebration of the coming of spring and the occasion of the first outing of the year. This paper discusses the historical development of the festival since prehistoric times,…

  10. Effects of traditional Chinese medicine on rats with Type II diabetes ...

    African Journals Online (AJOL)

    Effects of traditional Chinese medicine on rats with Type II diabetes induced by high-fat diet and streptozotocin: A urine metabonomic study. H Zhao, Z Li, G Tian, K Gao, Li Zhiyong, B Zhao, J Wang, L Luo, Q Pan, W Zhang, Z Wu, J Chen, W Wang ...

  11. Micro SR-XRF analysis on underglaze copper red porcelain of ming dynasty

    International Nuclear Information System (INIS)

    Guan Li; Zhu Jian; Yang Yimin; Fan Changsheng; Chen Dongliang; Xu Wei; Zhang Jing; Wang Lihua

    2013-01-01

    Background: The firing techniques of producing underglaze copper red porcelain emerged in the Yuan dynasty and reached its maturity during the Ming and Qing Dynasties in Jingdezhen city. The technique of producing underglaze red porcelain was sensitive to the firing temperature and atmosphere, so it was very hard to produce and also difficult to display red color under the surface successfully. Purpose and Methods: The micro SR-XRF technique was employed to analysis a piece of sherd of underglaze copper red porcelain of early Ming dynasty. The Chemical compositions of glaze and color areas were presented, and the elemental contents in different color areas were obtained by using line-scanning techniques. Results: Some elements such as As and Pb were contained in raw materials, and the content of Cu had obviously increased with the color changing from gray to red. The results indicated that the nature mineral possibly used as the pigment for underglazed copper red porcelain coloration, and the color appearance also depends on the amount of copper in the pigments contained. Conclusions: This paper presents the advantage of the synchrotron radiation XRF technology and contributes to the science evidences for the Chinese ancient porcelain handcraft research. (authors)

  12. Research Laboratory of Electronics Annual Report Number 125.

    Science.gov (United States)

    1983-01-01

    approximation for modeling underwater acoustics. The summers of 1983 and 1984 mark the beginning of a series of geophysical and acoustic experiments in the...conditions, modifications in an adaptive noise cancelling algorithm such as the Widrow- Hoff least mean square algorithm, allows one to still reduce the...Stephanie Brown, Fielding Kanbe, Hiroshi Vaidyanathan, A. Ganesh Buchinger, Fritz Kayoun, Pierre H. Wang, Hong.Ming Cerrillo, Manuel V. Konrad, Cristina Wang

  13. New Wang-Landau approach to obtain phase diagrams for multicomponent alloys

    Science.gov (United States)

    Takeuchi, Kazuhito; Tanaka, Ryohei; Yuge, Koretaka

    2017-10-01

    We develop an approach to apply the Wang-Landau algorithm to multicomponent alloys in a semi-grand-canonical ensemble. Although the Wang-Landau algorithm has great advantages over conventional sampling methods, there are few applications to alloys. This is because calculating compositions in a semi-grand-canonical ensemble via the Wang-Landau algorithm requires a multidimensional density of states in terms of total energy and compositions, and constructing it is difficult from the viewpoints of both implementation and computational cost. In this study, we develop a simple approach to calculate the alloy phase diagram based on the Wang-Landau algorithm, and show that a number of one-dimensional densities of states could lead to compositions in a semi-grand-canonical ensemble as a multidimensional density of states could. Finally, we apply the present method to Cu-Au and Pd-Rh alloys and confirm that the present method successfully describes the phase diagram with high efficiency, validity, and accuracy.

  14. Dr. Yu Wang, Director, Natural Science Division, National Science Council, Taiwan

    CERN Document Server

    Patrice Loïez

    2001-01-01

    Photo 01: L. to r.: Dr. Philippe Bloch, CERN CMS ECAL Deputy Project Manager, Dr. Yu Wang, Dr. Etiennette Auffray, CERN, responsible of the CERN ECAL Regional Centre. Photo 02: L. to r.: Dr. Yu Wang, Dr. Philippe Bloch, Dr. Apollo GO, National Central University, Taiwan, Dr. Etiennette Auffray.

  15. The study of ancient porcelain of Hutian kiln site from Five dynasty (902-979) to Ming dynasty (1368-1644) by INAA

    International Nuclear Information System (INIS)

    Lin Cheng; Junling Wang; Rongwu Li; Meitian Li

    2015-01-01

    Minor and trace elements of 398 pieces of ancient porcelain of Hutian kiln site from Five dynasty (AD 902-979) to Ming dynasty (AD 1368-1644) were determined by instrumental neutron activate analysis (INAA). The data of INAA and PCA show the ages of all the porcelain can be divided into Five dynasty, Northern Song dynasty, Southern Song dynasty, Early Yuan dynasty, Later Yuan dynasty and Ming dynasty according to their chemical compositions. Moreover, some archaeological questions about the ancient porcelain are discussion also. (author)

  16. P chromosomes involved in intergenomic rearrangements of ...

    Indian Academy of Sciences (India)

    2014-04-08

    Apr 8, 2014 ... [Wang Q., Han H., Gao A., Yang X. and Li L. 2014 P chromosomes ... Y, were affected predominantly by ecological factors and altitude in nine populations of Kengyilia thoroldiana (Wang et al. 2012). To investigate the effects of different altitudes on .... AB51 0LX, UK) for improving the article linguistically.

  17. Stamatina Dimakopoulou onMing-QianMa’s Poetry as Re-Reading

    Directory of Open Access Journals (Sweden)

    2010-05-01

    Full Text Available Ming-Qian Ma. Poetry as Re-Reading: American Avant-Garde Poetry and the Poetics of Counter-Method. Evanston, Illinois: Northwestern University Press, 2008. Pp. 301. ISBN 978-0810124851In the Preface to the 1979 Enlarging the Temple: New Directions in American Poetry during the 1960s – Charles Altieri formulated a re-alignment that defined much criticism of postwar and contemporary American poetry to come. Altieri set “the work of Heidegger and the later Wittgenstein,” in resonance with the “i...

  18. The political Thought of José Gaos. The Criticism of Totalitarianism

    Directory of Open Access Journals (Sweden)

    Antolín Sánchez Cuervo

    2017-01-01

    Full Text Available Jose Gaos's diverse writings are reviewed, many of them scantily known and still unpublished, related to the area of the politics in the wide sense of the term. It was the case of some reflections motivated by the global protagonism of the war, the totalitarianism and the technocracy in the current manners of life, including those that are typical of the democratic western companies. In line with this protagonism, Gaos raised a genealogical review of the secularizing process of modern rationality, which will connect with some of his big worries, such as the possibility of the philosophy itself and the possibility of the Hispanic philosophy especially.

  19. Browse Title Index

    African Journals Online (AJOL)

    Items 4251 - 4300 of 11090 ... Vol 9, No 4 (2010), Effects of mowing utilization on forage yield and quality in five oat varieties in alpine area of the eastern Qinghai-Tibetan Plateau, Abstract PDF. W Gao-Lin, W Mei-Ru, G Ting, H Tian-Ming, G Davidson. Vol 7, No 17 (2008), Effects of municipal sewage sludge doses on the yield, ...

  20. Tropical Journal of Pharmaceutical Research - Vol 15, No 3 (2016)

    African Journals Online (AJOL)

    Wan Wu, Wei Chen, Qiong Jin, 447-451 ... Chung-Shih Chen, Mei-Lin Wang, Rosa Huang Liu, Shih-Pin Chen, Tsong-Ming Lu, Wei-Yu Tsai, Chien-Fu Huang, ... Yan-Qiong Li, Rui Hu, Li-Hui Zhong, Qian Sun, You-Ping Yan, 527-533.

  1. Cryptanalysis of Wang et al.’s lattice-based key exchange protocol

    Directory of Open Access Journals (Sweden)

    Daya Sagar Gupta

    2016-09-01

    Full Text Available Wang et al. proposed a new hard problem on lattices which is an extension of the small integer solution (SIS on lattices. This new generated hard problem is named to be bilateral in-homogeneous small integer solution (Bi-ISIS. Using the hardness of Bi-ISIS, Wang et al. proposed a new key exchange protocol, which is based on the lattice-based cryptography. In this paper, we signalize that Wang et al.’s lattice-based key exchange protocol is vulnerable to an attack, namely, man-in-the-middle (MITM attack. Through this attack, Eavesdropper can intercept the authenticated messages and communicate the unauthentic messages among the communicating parties.

  2. Solution of Contact Problems for Nonlinear Gao Beam and Obstacle

    Directory of Open Access Journals (Sweden)

    J. Machalová

    2015-01-01

    Full Text Available Contact problem for a large deformed beam with an elastic obstacle is formulated, analyzed, and numerically solved. The beam model is governed by a nonlinear fourth-order differential equation developed by Gao, while the obstacle is considered as the elastic foundation of Winkler’s type in some distance under the beam. The problem is static without a friction and modeled either using Signorini conditions or by means of normal compliance contact conditions. The problems are then reformulated as optimal control problems which is useful both for theoretical aspects and for solution methods. Discretization is based on using the mixed finite element method with independent discretization and interpolations for foundation and beam elements. Numerical examples demonstrate usefulness of the presented solution method. Results for the nonlinear Gao beam are compared with results for the classical Euler-Bernoulli beam model.

  3. Compendium of GAO’s Views on the Cost Saving Proposals of the Grace Commission. Volume 2. Individual Issue Analyses

    Science.gov (United States)

    1985-02-19

    fashion , linking it to other management processes such as budgeting and operational planning. III. GAO ASSESSMENT OF IMPLEMENTATION AUTHORITY...research which private industy is able to conduct on its own. Past GAO work has illustrated the costs of duplica- tion. A 1982 GAO report on UMTA...could be increased approximately $4.9 million, over 3 years, if the average concessioner franchise fee were increased from 2 to 4 percent of gross

  4. GAOS: Spatial optimisation of crop and nature within agricultural fields

    NARCIS (Netherlands)

    Bruin, de S.; Janssen, H.; Klompe, A.; Lerink, P.; Vanmeulebrouk, B.

    2010-01-01

    This paper proposes and demonstrates a spatial optimiser that allocates areas of inefficient machine manoeuvring to field margins thus improving the use of available space and supporting map-based Controlled Traffic Farming. A prototype web service (GAOS) allows farmers to optimise tracks within

  5. Nuclear Energy: Compendium of relevant GAO products on regulation, health, and safety

    International Nuclear Information System (INIS)

    1986-01-01

    This report presents findings, conclusions, and recommendations in the areas of (1) protecting worker health and safety, (2) planning for nuclear emergencies and coordinating response mechanisms in the event of a serious nuclear accident, (3) ensuring the safe design of facilities, and (4) monitoring the environment. GAO points out that impaired organizational independence of the oversight function, a lack of headquarters authority, and the decentralized nature of the oversight activities may constitute serious problems over the long term. More recent GAO work indicates that organizational independence of the oversight function may still be a problem area and is likely to receive increased scrutiny in the aftermath of the Chernobyl nuclear reactor accident in the Soviet Union

  6. Fabrication and characterization of drug-loaded nano-hydroxyapatite/polyamide 66 scaffolds modified with carbon nanotubes and silk fibroin

    Directory of Open Access Journals (Sweden)

    Yao MZ

    2016-11-01

    Full Text Available Meng-Zhu Yao,1 Ming-Yi Huang-Fu,1 Hui-Na Liu,1 Xia-Rong Wang,1 Xiaoxia Sheng,2 Jian-Qing Gao1 1Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, 2Hangzhou SoliPharma Co., Ltd, Hangzhou, Zhejiang, People’s Republic of China Abstract: Nano-hydroxyapatite/polyamide 66 (nHA/PA66 porous scaffolds were fabricated by a phase inversion method. Carbon nanotubes (CNTs and silk fibroin (SF were used to modify the surface of the nHA/PA66 scaffolds by freeze-drying and cross-linking. Dexamethasone was absorbed to the CNTs to promote the osteogenic differentiation of bone mesenchymal stem cells (BMSCs. The cell viability of BMSCs was investigated by changing the concentration of the CNT dispersion, and the most biocompatible scaffold was selected. In addition, the morphology and mechanical property of the scaffolds were investigated. The results showed that the nHA/PA66 scaffolds modified with CNTs and SF met the requirements of bone tissue engineering scaffolds. The dexamethasone-loaded CNT/SF-nHA/PA66 composite scaffold promoted the osteogenic differentiation of BMSCs, and the drug-loaded scaffolds are expected to function as effective bone tissue engineering scaffolds. Keywords: BMSCs, tissue engineering, porous scaffold, carbon nanotubes, silk fibroin, surface modification, dexamethasone

  7. Anti-hepatitis B viral activity of Phyllanthus niruri L (Phyllanthaceae ...

    African Journals Online (AJOL)

    Yong Li, Xin Li, Jia-Kun Wang, Yan Kuang and Ming-Xiu Qi*. Centers for Disease .... sarkosyl, 7 % 2-mercaptoethanol, 4 M guanidine ..... AK, Gane E, Hou JL, Jafri W, Jia J, Kim JH, Lai CL, Lee. HC, Lim SG, Liu CJ ... Shin MS, Kang EH, Lee YI.

  8. ‘Unable to think in my mother’s tongue’: immigrant daughters in Alice Pung’s 'Unpolished Gem' and Hsu-Ming Teo’s 'Behind the Moon'

    OpenAIRE

    Alice Healy

    2010-01-01

    This paper explores ‘the immigrant’s story in translation’ through the various instances of language spoken between parents and children. It analyses the experience of immigrant daughters in two ‘Asian-Australian’ texts – Alice Pung’s recent memoir Unpolished Gem and Hsu-Ming Teo’s Behind the Moon. I position these texts in the context of the reception of literature labelled ‘Asian-Australian’ in the market, exploring Hsu-Ming Teo’s critique of such positioning. Centrally, the paper examine...

  9. Evaluating Small Sphere Limit of the Wang-Yau Quasi-Local Energy

    Science.gov (United States)

    Chen, Po-Ning; Wang, Mu-Tao; Yau, Shing-Tung

    2018-01-01

    In this article, we study the small sphere limit of the Wang-Yau quasi-local energy defined in Wang and Yau (Phys Rev Lett 102(2):021101, 2009, Commun Math Phys 288(3):919-942, 2009). Given a point p in a spacetime N, we consider a canonical family of surfaces approaching p along its future null cone and evaluate the limit of the Wang-Yau quasi-local energy. The evaluation relies on solving an "optimal embedding equation" whose solutions represent critical points of the quasi-local energy. For a spacetime with matter fields, the scenario is similar to that of the large sphere limit found in Chen et al. (Commun Math Phys 308(3):845-863, 2011). Namely, there is a natural solution which is a local minimum, and the limit of its quasi-local energy recovers the stress-energy tensor at p. For a vacuum spacetime, the quasi-local energy vanishes to higher order and the solution of the optimal embedding equation is more complicated. Nevertheless, we are able to show that there exists a solution that is a local minimum and that the limit of its quasi-local energy is related to the Bel-Robinson tensor. Together with earlier work (Chen et al. 2011), this completes the consistency verification of the Wang-Yau quasi-local energy with all classical limits.

  10. Metagenomics and in situ analyses reveal Propionivibrio spp. to be abundant GAO in biological wastewater treatment systems

    DEFF Research Database (Denmark)

    McIlroy, Simon Jon; Albertsen, Mads; Stokholm-Bjerregaard, Mikkel

    Enhanced biological phosphorus removal (EBPR) is widely applied for phosphorus removal from wastewater. The process relies on polyphosphate-accumulating organisms (PAOs) that are able to take up phosphorus in excess of what is needed for growth. However, glycogen-accumulating organisms (GAOs) may...... reduce the EBPR efficiency as they compete for substrates with PAOs, but do not store excess polyphosphate. “Candidatus Accumulibacter” is widely considered to be the important PAO. In this study a laboratory scale sequencing batch reactor was operated for EBPR for the enrichment of “Ca. Accumulibacter......”. Applying the PAOmix probe set, routinely applied to target the “Ca. Accumulibacter”, suggested a PAO enrichment of 70% of the biovolume by FISH. Known GAOs were detected in low abundance with FISH (PAO and GAO...

  11. Nd3-xBixFe4GaO12 (x = 2, 2.5 films on glass substrates prepared by MOD method

    Directory of Open Access Journals (Sweden)

    Yoshida T.

    2014-07-01

    Full Text Available We studied Nd3-XBiXFe4GaO12 films to obtain perpendicular magnetic anisotropy as well as large Faraday effect. NdBi2Fe4GaO12 (Bi2:NIGG and Nd0.5Bi2.5Fe4GaO12 (Bi2.5:NIGG films were obtained on Nd2BiFe4GaO12 (Bi1:NIGG layer prepared on glass substrates by metal-organic decomposition (MOD method. Bi2:NIGG and Bi2.5:NIGG films showed large Faraday rotation angles of 7.5 and 10.5 degree/µm, at a wavelength of 520 nm, respectively. Those films have perpendicular magnetic anisotropy with a coercivity of 350 Oe and a saturation magnetic field of 730 Oe.

  12. Properties, characterization, and decay of sticky rice–lime mortars from the Wugang Ming dynasty city wall (China)

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Ya [State Key Laboratory for Powder Metallurgy, Central South University, Changsha 410083 (China); Cultural Relics and Archaeology Institute of Hunan, Changsha 410083 (China); Fu, Xuan; Gu, Haibing [Cultural Relics and Archaeology Institute of Hunan, Changsha 410083 (China); Gao, Feng [State Key Laboratory for Powder Metallurgy, Central South University, Changsha 410083 (China); Liu, Shaojun, E-mail: liumatthew@csu.edu.cn [State Key Laboratory for Powder Metallurgy, Central South University, Changsha 410083 (China)

    2014-04-01

    Urgent restoration of the Wugang Ming dynasty city wall brings about the need for a study of the formulation and properties of mortars. In the present paper, mortar samples from the Wugang Ming dynasty city wall were characterized in a combination of sheet polarized light optical microscopy, scanning electron microscopy with X-ray energy dispersive spectrometer, thermogravimetric/differential scanning calorimetry, X-ray powder diffraction, Fourier transform infrared spectroscopy, and inductively coupled plasma emission spectroscopy. Results show that mortars are mainly built up from inorganic calcium carbonate based organic–inorganic hybrid material with a small amount of sticky rice, which plays a crucial role in forming dense and compact microstructure of mortars and effectively hindering penetration of water and air into mortars. Analysis of decayed products shows that the detrimental soluble salts originates from ambient environment. - Highlights: • Mortars used in the Wugang city wall are a calcium carbonate-sticky rice hybrid bonding material. • Carbonation processing is extremely slow due to dense and compact microstructure of mortars. • Decying of mortars results from the appearance of soluble salt from ambient environment.

  13. Properties, characterization, and decay of sticky rice–lime mortars from the Wugang Ming dynasty city wall (China)

    International Nuclear Information System (INIS)

    Xiao, Ya; Fu, Xuan; Gu, Haibing; Gao, Feng; Liu, Shaojun

    2014-01-01

    Urgent restoration of the Wugang Ming dynasty city wall brings about the need for a study of the formulation and properties of mortars. In the present paper, mortar samples from the Wugang Ming dynasty city wall were characterized in a combination of sheet polarized light optical microscopy, scanning electron microscopy with X-ray energy dispersive spectrometer, thermogravimetric/differential scanning calorimetry, X-ray powder diffraction, Fourier transform infrared spectroscopy, and inductively coupled plasma emission spectroscopy. Results show that mortars are mainly built up from inorganic calcium carbonate based organic–inorganic hybrid material with a small amount of sticky rice, which plays a crucial role in forming dense and compact microstructure of mortars and effectively hindering penetration of water and air into mortars. Analysis of decayed products shows that the detrimental soluble salts originates from ambient environment. - Highlights: • Mortars used in the Wugang city wall are a calcium carbonate-sticky rice hybrid bonding material. • Carbonation processing is extremely slow due to dense and compact microstructure of mortars. • Decying of mortars results from the appearance of soluble salt from ambient environment

  14. Microbial Impacts to the Near-Field Environment Geochemistry (MING): A Model for Estimating Microbial Communities in Repository Drifts at Yucca Mountain

    International Nuclear Information System (INIS)

    Jolley, D.M.; Ehrhorn, T.F.; Horn, J.

    2002-01-01

    Geochemical and microbiological modeling was performed to evaluate the potential quantities and impact of microorganisms on the geochemistry of the area adjacent to and within nuclear waste packages in the proposed repository drifts at Yucca Mountain, Nevada. The microbial growth results from the introduction of water, ground support, and waste package materials into the deep unsaturated rock. The simulations, which spanned one million years, were accomplished using a newly developed computer code, Microbial Impacts to the Near-Field Environment Geochemistry (MING). MING uses environmental thresholds for limiting microbial growth to temperatures below 120 C and above relative humidities of 90 percent in repository drifts. Once these thresholds are met, MING expands upon a mass balance and thermodynamic approach proposed by McKinley and others (1997), by using kinetic rates to supply constituents from design materials and constituent fluxes including solubilized rock components into the drift, to perform two separate mass-balance calculations as a function of time. The first (nutrient limit) assesses the available nutrients (C, N, P and S) and calculates how many microorganisms can be produced based on a microorganism stoichiometry of C 160 (H 280 O 80 )N 30 P 2 S. The second (energy limit) calculates the energy available from optimally combined redox couples for the temperature, and pH at that time. This optimization maximizes those reactions that produce > 15kJ/mol (limit on useable energy) using an iterative linear optimization technique. The final available energy value is converted to microbial mass at a rate of 1 kg of biomass (dry weight) for every 64 MJ of energy. These two values (nutrient limit and energy limit) are then compared and the smaller value represents the number of microorganisms that can be produced over a specified time. MING can also be adapted to investigate other problems of interest as the model can be used in saturated and unsaturated

  15. Author Details

    African Journals Online (AJOL)

    Wang, Ming-Rui. Vol 13, No 2 (2016) - Articles Effects of acupuncture on rheumatoid arthritis: a systematic review and meta-analysis. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

  16. Pinoresinol diglucoside exhibits protective effect on dexamethasone ...

    African Journals Online (AJOL)

    Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 ... Zhan-Feng Zhang, Ji-Kang Min, Dan Wang, Jian-Ming Zhong* .... mineral density meter (Beijing Zhongxi Yuanda ..... Svedbom A, Ivergård M, Hernlund E, Rizzoli R, Kanis JA. ... Pan Y, Niu Y, Li C, Zhai Y, Zhang R, Guo X, Mei Q. Du-.

  17. Estimating the Partition Function Zeros by Using the Wang-Landau Monte Carlo Algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung-Yeon [Korea National University of Transportation, Chungju (Korea, Republic of)

    2017-03-15

    The concept of the partition function zeros is one of the most efficient methods for investigating the phase transitions and the critical phenomena in various physical systems. Estimating the partition function zeros requires information on the density of states Ω(E) as a function of the energy E. Currently, the Wang-Landau Monte Carlo algorithm is one of the best methods for calculating Ω(E). The partition function zeros in the complex temperature plane of the Ising model on an L × L square lattice (L = 10 ∼ 80) with a periodic boundary condition have been estimated by using the Wang-Landau Monte Carlo algorithm. The efficiency of the Wang-Landau Monte Carlo algorithm and the accuracies of the partition function zeros have been evaluated for three different, 5%, 10%, and 20%, flatness criteria for the histogram H(E).

  18. Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment | Poster

    Science.gov (United States)

    Noriho Iida, Amiran Dzutsev, C. Andrew Stewart, Loretta Smith, Nicolas Bouladoux, Rebecca A. Weingarten, Daniel A. Molina, Rosalba Salcedo, Timothy Back, Sarah Cramer, Ren-Ming Dai, Hiu Kiu, Marco Cardone, Shruti Naik, Anil K. Patri, Ena Wang, Francesco M. Marincola, Karen M. Frank, Yasmine Belkaid, Giorgio Trinchieri, Romina S. Goldszmid Science 342(6161):967-970, 2013

  19. Download this PDF file

    African Journals Online (AJOL)

    cadewumi

    1,3, Wen-Chi Chen*4. 1Department of Urology, Chang Bing Show Chwan Memorial Hospital, 2Department of Life ..... with WLS was first recorded in the book written by Ken-Tang Wang entitled “Zheng Zhi Zhun Sheng” (standards of patterns and treatment) during the Ming Dynasty (late sixteenth century). Since that time, the ...

  20. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yan-Qin Xu Guo-Yan Wei Yin Zhou Fei Ge Guang-Ming Luo · More Details Fulltext PDF. pp e25-e28. Abundance and characteristics of microsatellite markers in Gansu zokor (Eospalax cansus), a fossorial rodent endemic to the Loess plateau, China · Junhu Su Limin Hua Jing Wang Dianne M. Gleeson Yanming Wei Robyn ...

  1. Rigorous lower bound on the dynamic critical exponent of some multilevel Swendsen-Wang algorithms

    International Nuclear Information System (INIS)

    Li, X.; Sokal, A.D.

    1991-01-01

    We prove the rigorous lower bound z exp ≥α/ν for the dynamic critical exponent of a broad class of multilevel (or ''multigrid'') variants of the Swendsen-Wang algorithm. This proves that such algorithms do suffer from critical slowing down. We conjecture that such algorithms in fact lie in the same dynamic universality class as the stanard Swendsen-Wang algorithm

  2. Shape tunable synthesis of Eu- and Sm-doped ZnO microstructures ...

    Indian Academy of Sciences (India)

    Shape tunable synthesis of Eu- and Sm-doped ZnO microstructures: a morphological ... different microstructures material at relatively low temper- ..... Chem. C 114. 2776. 5. Gao P X and Wang Z L 2003 J. Am. Chem. Soc. 125 11299. 6.

  3. Myometrial invasion and overall staging of endometrial carcinoma: assessment using fusion of T2-weighted magnetic resonance imaging and diffusion-weighted magnetic resonance imaging

    OpenAIRE

    Guo, Yu; Wang, Ping; Wang, Penghui; Gao, Wei; Li, Fenge; Yang, Xueling; Ni, Hongyan; Shen, Wen; Guo, Zhi

    2017-01-01

    Yu Guo,1,2 Ping Wang,2 Penghui Wang,2 Wei Gao,1 Fenge Li,3 Xueling Yang,1 Hongyan Ni,2 Wen Shen,2 Zhi Guo1 1Department of Interventional Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, 2Department of Radiology, Tianjin First Center Hospital, The First Central Clinical College of Tianjin Medical University,...

  4. Efficacy of Chinese herbal medicine Zengru Gao to promote breastfeeding: a multicenter randomized controlled trial.

    Science.gov (United States)

    Wang, Shuaishuai; Zhang, Chi; Li, Cuishan; Li, Daocheng; He, Ping; Su, Zhaojuan; Li, Yanling; Ding, Yiling; Lu, Aiping

    2018-02-06

    Breastfeeding is recommended worldwide but not fully practiced. The first week after childbirth is regarded as a critical period for increasing breast milk production. The aim of the study was to investigate whether Chinese herbal medicine Zengru Gao would result in more women breastfeeding in the first week after childbirth. A multicenter randomized controlled trial was conducted of 588 mothers considering breastfeeding in China. Among the mothers of the intervention group, the intervention included Chinese herbal medicine Zengru Gao; among those of the control group, it did not. Primary outcomes were the percentages of fully and partially breastfeeding mothers. Secondary outcome was baby's daily formula intake. At 3 d and 7 d after delivery, significant differences were found in favour of Zengru Gao group on the percentage of full/ partial breastfeeding (Z = - 3.0037, p = 0.0027). At day 7, the percentage of full/ partial breastfeeding of the active group increased to 71.48%/20.70% versus 58.67%/30.26% in the control group, the differences remained significant (Z = - 3.0037, p = 0.0027). No statistically significant differences were detected on primary measures at 1 d. While intake of formula differed between groups at 1 d and 3 d, this difference did not achieve statistical significance, but this difference was apparent by 7 d (55.45 ± 115.39 ml/day vs 90.66 ± 153.89 ml/day). In conclusion, Chinese Herbal medicine Zengru Gao enhanced breastfeeding success during one week postpartum. The approach is acceptable to participants and merits further evaluation. ChiCTR-IPR-15007376 , December 11, 2015.

  5. Pedestrian Dharma: Slowness and Seeing in Tsai Ming-Liang’s Walker

    Directory of Open Access Journals (Sweden)

    Teng-Kuan Ng

    2018-06-01

    Full Text Available This paper studies the ways that Walker, a short film by the Malaysian-Taiwanese auteur Tsai Ming-Liang, visualizes the relationship between Buddhism and modernity. Via detailed film analysis as well as attention to sources in premodern Buddhist traditions, this paper argues that its filmic performance of Zen walking meditation serves two functions: To present slowness and simplicity as prophetic counterpoints against the dizzying excesses of the contemporary metropolis; and to offer contemplative attentiveness as a therapeutic resource for life in the modern world. By instantiating and cultivating critical shifts in viewerly perspective in the manner of Buddhist ritual practice, Walker invites us to envision how a place of frenetic distraction or pedestrian mundaneness might be transfigured into a site of beauty, wonder, and liberation.

  6. Microbial Impacts to the Near-Field Environment Geochemistry (MING): A Model for Estimating Microbial Communities in Repository Drifts at Yucca Mountain

    Energy Technology Data Exchange (ETDEWEB)

    D.M. Jolley; T.F. Ehrhorn; J. Horn

    2002-03-19

    Geochemical and microbiological modeling was performed to evaluate the potential quantities and impact of microorganisms on the geochemistry of the area adjacent to and within nuclear waste packages in the proposed repository drifts at Yucca Mountain, Nevada. The microbial growth results from the introduction of water, ground support, and waste package materials into the deep unsaturated rock. The simulations, which spanned one million years, were accomplished using a newly developed computer code, Microbial Impacts to the Near-Field Environment Geochemistry (MING). MING uses environmental thresholds for limiting microbial growth to temperatures below 120 C and above relative humidities of 90 percent in repository drifts. Once these thresholds are met, MING expands upon a mass balance and thermodynamic approach proposed by McKinley and others (1997), by using kinetic rates to supply constituents from design materials and constituent fluxes including solubilized rock components into the drift, to perform two separate mass-balance calculations as a function of time. The first (nutrient limit) assesses the available nutrients (C, N, P and S) and calculates how many microorganisms can be produced based on a microorganism stoichiometry of C{sub 160}(H{sub 280}O{sub 80})N{sub 30}P{sub 2}S. The second (energy limit) calculates the energy available from optimally combined redox couples for the temperature, and pH at that time. This optimization maximizes those reactions that produce > 15kJ/mol (limit on useable energy) using an iterative linear optimization technique. The final available energy value is converted to microbial mass at a rate of 1 kg of biomass (dry weight) for every 64 MJ of energy. These two values (nutrient limit and energy limit) are then compared and the smaller value represents the number of microorganisms that can be produced over a specified time. MING can also be adapted to investigate other problems of interest as the model can be used in saturated

  7. Non-enzymatic hydrogen peroxide sensor based on Co 3 O 4 ...

    Indian Academy of Sciences (India)

    Author Affiliations. Guang Sheng Cao1 Lei Wang1 Pengfei Yuan1 Chao Gao1 Xiaojuan Liu1 Tong Li1 Tianmin Li1. Key Laboratory of Enhanced Oil and Gas Recovery of Ministry of Education, Northeast Petroleum University, Daqing 163318, China ...

  8. African Journal of Biotechnology - Vol 8, No 6 (2009)

    African Journals Online (AJOL)

    Single nucleotide polymorphism genotyping and its application on mapping and marker-assisted plant breeding ... HH Musa, Y Xu, B Dai, X Kang, C Zhu, G Zhu ... YJ Wang, ZQ Han, B Shui, GD Liu, TX Gao, SA Nwafili, S Watanabe, YP Zhang ...

  9. White-and-blud porcelain of Hutian kiln in Ming dynasty studied by PIXE

    International Nuclear Information System (INIS)

    Cheng Lin; Feng Songlin; Sha Yin; Cheng Huansheng

    2004-01-01

    The study of provenance, ages and distinguishing precious ancient porcelain from a fake of Chinese ancient porcelain by modern technologies arose greatly interesting in the circles of archaeologists and scientists in China. Concentration of major and trace elements of white-and-blue porcelain of Hutian kiln in Ming Dynasty were analyzed by PIXE, and elemental distributions of porcelain were analyzed by SPM. The results indicate the elemental distributions in the white glaze, blue glaze and body are homogeneous, respectively. It is a layer nearly 5-10 μm between the body and blue glaze. Probably, cobalt blue pigment used in the blue glaze comes from Jiangxi, Fujian province etc. (authors)

  10. [Exploration on an overview of history (from Chunqiu to Ming and Qing Dynasties) and species of Chinese exotic traditional medicine].

    Science.gov (United States)

    Jia, Min-Ru; Wang, Tian-Tian; Lu, Xiao-Lin; Ma, Yu-Ying

    2017-05-01

    This paper collected and analyzed literatures about starting of traditional medicine and trading of different medicine from Chunqiu Zhanguo to Ming and Qing Dynasties, in order to preliminarily explore on an overview of specie of chinese exotic traditional medicine and trade of different country in different dynasty(from Chunqiu to Ming and Qing Dynasties), as well as the amount of exotic medicine over two thousand years. (remove repeating and doubtful species), find peculiarity of exotic medicine, sreen species that used to develop the Silk Route and establish quality standards.Finally, We get conclusions are as follows. First, primary,.prosperous and declining stages of development of exotic traditional medicine are Qin and Han, Song-Jin-Yuan, Ming and Qing Dynasties, respectively. Second, according to literature, the stage that has the most species of exotic medicine is song dynasty,approximately have 300. Removing repeating and doubtful species, the believable species are approximate 230 to 250. Meanwhile, the unknown species are approximate 30, which may be different name of one medicine or processed goods, now these medicines are named as "doubtful species". Third, the medicinal parts of exotic medicine are different from Chinese medicine of Han nation. The number of Resin, fruits and seeds kind are more than root and rhizomes kind,mineral medicines are more than animal. Fourth, the major producing area of exotic medicine is some countries and territories related to the Silk Route in the history. Ultimately, this paper preliminarily figure out basic information of exotic medicine of different dynasty in China,that provide reference for learning study and decision of industrial development. Copyright© by the Chinese Pharmaceutical Association.

  11. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. YOU-LIANG ZHENG. Articles written in Journal of Genetics. Volume 92 Issue 1 April 2013 pp 151-154 Research Note. Identification of 40k -secalin genes · Peng-Fei Qi Qing Chen Thérèse Ouellet Cheng-Xing Le Jia Ai Yu-Ming Wei Ji-Rui Wang You-Liang Zheng · More Details Fulltext ...

  12. The γ-gliadin-like γ-prolamin genes in the tribe Triticeae

    Indian Academy of Sciences (India)

    Supplementary data: The γ-gliadin-like γ-prolamin genes in the tribe Triticeae. Peng-Fei Qi, Cheng-Xing Le, Zhao Wang, Yu-Bin Liu, Qing Chen, Zhen-Zhen Wei, Bin-Jie Xu, Zheng-Yuan Wei,. Shou-Fen Dai, Yu-Ming Wei and You-Liang Zheng. J. Genet. 93, 35–41. Table 1. The γ-prolamin genes of diploid Triticeae species.

  13. Influences of protective atmosphere on the characterization and ...

    Indian Academy of Sciences (India)

    tective atmosphere on the characterization and properties of the ceramics were investigated. All the ceramics showed ... Tian-Hang Zhang et al temperature and ..... Soc. 24 3731. 20. Wang Y, Zhang Y C, Hu Z J, Gao X, Guo X F and Jiang Y J.

  14. Silverization of China during the Ming-Qing Transition (ca. 1550-1700) and the Consequences for Research into the Babylonian Economy

    NARCIS (Netherlands)

    van Leeuwen, Bas; XU, Yi; Kleber, Kristin; Pirngruber, Reinhard

    2016-01-01

    In a recent publication, Prof. Van der Spek (2011) made an intriguing comparison between the flows of silver in the Chinese economy at the end of the Ming dynasty and in Babylonia ca. 400-60 BC. He concluded that in China the expansion of the silver economy worked positively for economic growth,

  15. On a conjecture of Chen-Guo-Wang

    OpenAIRE

    Ning, Bo; Zheng, Yu

    2015-01-01

    Towards confirming Sun's conjecture on the strict log-concavity of combinatorial sequence involving the n$th$ Bernoulli number, Chen, Guo and Wang proposed a conjecture about the log-concavity of the function $\\theta(x)=\\sqrt[x]{2\\zeta(x)\\Gamma(x+1)}$ for $x\\in (6,\\infty)$, where $\\zeta(x)$ is the Riemann zeta function and $\\Gamma(x)$ is the Gamma function. In this paper, we first prove this conjecture along the spirit of Zhu's previous work. Second, we extend Chen et al.'s conjecture in the ...

  16. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. G. D. Yang1 K. Yan1 B. J. Wu1 Y. H. Wang1 Y. X. Gao1 C. C. Zheng1. State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an, Shandong 271018, People's Republic of China ...

  17. A note on Wang et al's attack on Zhang et al's multiparty quantum secret sharing

    International Nuclear Information System (INIS)

    Gao Gan

    2012-01-01

    Recently, Wang et al (2008 Phys. Lett. A 373 65) proposed an attack on Zhang et al's (2007 Opt. Commun. 269 418) multiparty quantum secret sharing scheme, in which the first and the last agent are reported to be able to cooperatively eavesdrop on all the secret messages without being detected. In this paper, we show that in Wang et al's attack, on average no more than half the secret messages can be eavesdropped. (paper)

  18. Writers and Their Maps: The Construction of a GAO Report on Sexual Harassment.

    Science.gov (United States)

    Cook, Kelli Cargile

    2000-01-01

    Examines a 1994 General Accounting Office (GAO) report on sexual harassment at U.S. service academies to determine how power structures affected the report writers' rhetorical choices. Identifies what is valued and devalued in the report's contents. Describes Congress's reaction to the report and speculates on the report's impact on public…

  19. Research on the Distribution and Characteristics of Moso Ethnic Costume during the Ming and Qing Dynasties

    Institute of Scientific and Technical Information of China (English)

    YANG Linjun

    2014-01-01

    The “Moso” (麽些) during the Ming and Qing dynasties includes present day Naxi, as well as the present day Mongolians in the areas of Muli, Yanyuan, and the “Nari” and“Namuyi” branches of the Tibetan . The Moso were distributed in the present day area of Lijiang , Diqing, Nujiang;the Mangkang area of Changdu;the Muli, Yanyuan, and Yanbian areas of Liangs-han Prefecture; and Batang and Litang of Ganzi Prefecture .Due to the special geographic environ-ment as well as policies implemented by various dynasties regarding the ethnic people in the border areas, the Moso formed a kind of culture with their own characteristics during the long process of histo-ry.In different historical periods , the Moso's cos-tume and culture also differed-some parts there were passed down , but there was also innovation and development .The regional characteristics of the Moso costume were obvious during the Ming and Qing dynasties.This article, from the perspec-tive historical geography , will discuss the geo-graphical distribution , evolution and formation of Moso costume during the Ming and Qing periods .   Costume is a marker of an “ethnic group” , and it includes both clothes and ornaments .Seen from the vertical line of history , the costume of Moso people has various characteristics in various periods;and seen from the horizontal line of histo-ry, the costume has very obvious regional differ-ences.There are few records on Moso costumes before the Ming dynasty .Only a few records are found, for example, in the shiji· xinanyi liezhuan ( An Account of the Southwestern Yi in The Records of the Historian) , xintangshu· nanman zhuan ( An Account of the Southern Barbarians in the New Tang History) .Since the Ming dynasty , there are more records about the Moso in Han Chinese litera-ture in which new characteristics of Moso costume could be noted .A kind of regional distribution of Moso costume appeared , including the Lijiang cos-tume zone , and the Yanyuan

  20. Deterministic integer multiple firing depending on initial state in Wang model

    Energy Technology Data Exchange (ETDEWEB)

    Xie Yong [Institute of Nonlinear Dynamics, MSSV, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an 710049 (China)]. E-mail: yxie@mail.xjtu.edu.cn; Xu Jianxue [Institute of Nonlinear Dynamics, MSSV, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an 710049 (China); Jiang Jun [Institute of Nonlinear Dynamics, MSSV, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an 710049 (China)

    2006-12-15

    We investigate numerically dynamical behaviour of the Wang model, which describes the rhythmic activities of thalamic relay neurons. The model neuron exhibits Type I excitability from a global view, but Type II excitability from a local view. There exists a narrow range of bistability, in which a subthreshold oscillation and a suprathreshold firing behaviour coexist. A special firing pattern, integer multiple firing can be found in the certain part of the bistable range. The characteristic feature of such firing pattern is that the histogram of interspike intervals has a multipeaked structure, and the peaks are located at about integer multiples of a basic interspike interval. Since the Wang model is noise-free, the integer multiple firing is a deterministic firing pattern. The existence of bistability leads to the deterministic integer multiple firing depending on the initial state of the model neuron, i.e., the initial values of the state variables.

  1. Deterministic integer multiple firing depending on initial state in Wang model

    International Nuclear Information System (INIS)

    Xie Yong; Xu Jianxue; Jiang Jun

    2006-01-01

    We investigate numerically dynamical behaviour of the Wang model, which describes the rhythmic activities of thalamic relay neurons. The model neuron exhibits Type I excitability from a global view, but Type II excitability from a local view. There exists a narrow range of bistability, in which a subthreshold oscillation and a suprathreshold firing behaviour coexist. A special firing pattern, integer multiple firing can be found in the certain part of the bistable range. The characteristic feature of such firing pattern is that the histogram of interspike intervals has a multipeaked structure, and the peaks are located at about integer multiples of a basic interspike interval. Since the Wang model is noise-free, the integer multiple firing is a deterministic firing pattern. The existence of bistability leads to the deterministic integer multiple firing depending on the initial state of the model neuron, i.e., the initial values of the state variables

  2. Genetic variation of indigenous chicken breeds in China and a ...

    African Journals Online (AJOL)

    huis

    Genetic variation of indigenous chicken breeds in China and a Recessive White breed using AFLP fingerprinting. Yushi Gao. 1,2#. , Yunjie Tu. 1,2. , Haibin Tong. 1. , Kehua Wang. 1. , Xiujun Tang. 1 and Kuanwei Chen. 1. 1 Institute of Poultry, Academy of Agricultural Sciences in China, Yangzhou, 225003, Jiangsu, China.

  3. Proteomic identification of CIB1 as a potential diagnostic factor in ...

    Indian Academy of Sciences (India)

    Proteomic identification of CIB1 as a potential diagnostic factor in hepatocellular carcinoma. Tong Junrong Zhou Huancheng H E Feng Gao Yi Yang Xiaoqin Luo Zhengmao Zhang Hong Zeng Jianying Wang Yin Huang Yuanhang Zhang Jianlin Sun Longhua He Guolin. Articles Volume 36 Issue 4 September 2011 pp 659- ...

  4. The ABCs of Chinese Pop: Wang Leehom and the Marketing of a Global Chinese Celebrity

    Directory of Open Access Journals (Sweden)

    Grace Wang

    2012-06-01

    Full Text Available How did singer Wang Leehom, a Chinese American raised in the suburbs of New York, end up becoming one of the industry heavyweights of Mandopop (Mandarin-language pop music? This essay uses Wang as a case study to investigate how discourses of race, market, and belonging are reworked in global contexts. Drawing on Sau-ling Wong’s theoretical insights on transnational processes of race, citizenship, and belonging, it argues that Wang capitalizes on a fluid dynamic of sameness and difference to appeal to a heterogeneous Chinese-speaking audience that stretches across China to Taiwan, Hong Kong, Southeast Asia, and the greater Chinese diaspora. Through an examination of the racial and national contexts that frame Wang’s participation in Mandopop, this essay analyzes the particular calibrations of Chineseness that emerge from the singer’s music and public image and the imperfect translation of identities such as Chinese American, Chinese diasporic, and Chinese across diverse linguistic and national communities.

  5. Effects of Land Use Change on Sediment and Water Yields in Yang Ming Shan National Park, Taiwan

    Directory of Open Access Journals (Sweden)

    Thomas C. C. Huang

    2015-01-01

    Full Text Available The Soil and Water Assessment Tool (SWAT is a watershed-based, semi-distributed hydrologic model for simulating hydrological processes at different spatial scales. The SWAT hydrology and erosion/sediment components are first validated after the hydrologic components calibration. The SWAT model also utilizes geographic information system (GIS and digital elevation model (DEM to delineate watersheds and extract the stream network. This study applies SWAT model to assess the impacts of land use change on soil and water losses from Yang Ming Shan National Park Watershed in northern Taiwan. Although the government has formulated regulations to limit the development, however, intense human activities, such as farming and building construction, still continue to exist. This study utilized two land-use data periods, one in 1996 and another in 2007, along with the SWAT model to simulate soil and water losses in Yang Ming Shan National Park. Based on the baseline scenario, the SWAT model was also successful in simulating the future scenario. Study results for scenario 2007, as compared to 1996 baseline period indicate that land use change shows forest land decreases about 6.9%, agricultural land increases about 9.5%, and causes sediment yield increase of 0.25 t/ha. Human activities deserve more attention when assessing soil and water losses because of their inevitable impacts. Government needs to modify land development policies and plans for land use change detection using satellite imagery to avoid illegal development activities.

  6. THE APPLICATION OF SURVEY IN ER WANG TEMPLE RESTITUTING

    Directory of Open Access Journals (Sweden)

    W. Shuai

    2013-07-01

    Full Text Available Er Wang Temple, in World Heritage Site "Dujiang Weirs and Qingchengshan Mountai", was severely destroyed in Wenchuan earthquake of May 2008. There are several problems at different level in every building, such as structural distortion, foundation displacement, wall fracture, roof damage, etc. The stage was completely collapsed in the earthquake. Tableland the stage situated had a huge crack and slope collapse. This article is for the stage renovation. The survey of damage in earthquake is the basis of Er Wang Temple restituting. Survey including field survey after the earthquake and the measurement and investigation for the remained construction member of the main wood structure. For field survey, the basis of pillars which had not have significantly affects in earthquake could be seem as the reference points for measurement. The investigation of remained main wood construction member, especially the size of the key structures and site and manufacture method of the joints, is the important basis for recovery stage. Our team did our utmost to restore the original appearance of stage in design, materials and craft by various tools, which include measured drawings in different times, old images collection, fine measuring by 3D laser scan, measurement of leftover pieces, logical inference.

  7. Tropical Journal of Pharmaceutical Research - Vol 13, No 5 (2014)

    African Journals Online (AJOL)

    Optimization and Composition of Volatile Oil from Polygonatum odoratum (Mill Druce) using Supercritical Fluid Extraction · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. X Zhao, J Zeng, H Gao, Y Wang, 779-786. http://dx.doi.org/10.4314/tjpr.v13i5.19 ...

  8. [Professor WANG Fuchun's experience in the acupoint selection of clinical treatment with acupuncture and moxibustion].

    Science.gov (United States)

    Jiang, Hailin; Liu, Chengyu; Ha, Lijuan; Li, Tie

    2017-11-12

    Professor WANG Fuchun 's experience in the acupoint selection of clinical treatment with acupuncture and moxibustion was summarized. The main acupoints are selected by focusing on the chief symptoms of disease, the supplementary points are selected by differentiating the disorders. The acupoints are modified in terms of the changes of sickness. The effective acupoints are selected flexibly in accordance with the specific effects of points. The summary on the acupoint selection reflects professor WANG Fuchun 's academic thoughts and clinical experience and effectively instructs the clinical practice of acupuncture and moxibustion.

  9. [Experience summary of professor WANG Fuchun's "Zhenjing Anshen" acupuncture method for insomnia].

    Science.gov (United States)

    Li, Tie; Ha, Lijuan; Cao, Fang; Zhi, Mujun; Wang, Fuchun

    2015-11-01

    The experience of "Zhenjing Anshen" acupuncture method originally created by professor WANG Fuchun for treatment of insomnia was introduced in this paper. From aspects of insomnia pathogenesis, theoretical foundation, characteristics of acupoint selection, needing methods, needing time, etc., the experience of Professor WANG Fuchun for treatment of insomnia was explained. The "Zhenjing Anshen" acupuncture method proposed, for the first time, "new three layers" method of acupoint selection, including Sishencong (EX-HN 1), Shenmen (HT 7), Sanyinjiao (SP 6). This method presents the principles of acupoint selection along meridian, acupoint selection based on essence-qi-spirit, harmony of yin and yang. The acupuncture manipulation is emphasized, and treating time (the period of the day from 3 pm to 5 pm) is focused on; acupoint selection is simple but essential, and acupoint combination is scientific, which receives notable therapeutic effect in clinic.

  10. A power law of order 1/4 for critical mean field Swendsen-Wang dynamics

    CERN Document Server

    Long, Yun; Ning, Weiyang; Peres, Yuval

    2014-01-01

    The Swendsen-Wang dynamics is a Markov chain widely used by physicists to sample from the Boltzmann-Gibbs distribution of the Ising model. Cooper, Dyer, Frieze and Rue proved that on the complete graph K_n the mixing time of the chain is at most O(\\sqrt{n}) for all non-critical temperatures. In this paper the authors show that the mixing time is \\Theta(1) in high temperatures, \\Theta(\\log n) in low temperatures and \\Theta(n^{1/4}) at criticality. They also provide an upper bound of O(\\log n) for Swendsen-Wang dynamics for the q-state ferromagnetic Potts model on any tree of n vertices.

  11. The Dangers of 'Warming and Replenishing' (wenbu ) during the Ming to Qing Epistemic Transition.

    Science.gov (United States)

    de Vries, Leslie

    2015-01-01

    Through a case study of Zhao Xianke's One Principle through Medicine ( Yiguan ) (1617?) and Xu Dachun's (1693-1771) denouncements of this text, my article zooms in on divergent discourses on the safety and efficacy of medicinal substances and compounds in late imperial China. Although Xu Dachun's fierce attacks on the popular 'warming and replenishing' ( wenbu ) therapies can be situated in an epistemic shift from the cosmology of 'Song learning' ( songxue ) towards the philology of 'Han learning' ( hanxue ) and 'evidential research' ( kaozheng ), I argue that more complex issues were at stake as well. Changed political, social, ethical, and economic realities shaped new and multifaceted perceptions of the nature of medicine, the medical profession, and the usage of medicinals in the aftermath of the Ming to Qing transition.

  12. [Professor WANG Yin's academic thoughts and clinical application of acupuncture for spleen-sto-mach care].

    Science.gov (United States)

    Niu, Hua; Cao, Haibo; Wang, Yin

    Professor WANG Yin 's academic thoughts and clinical application for difficult and miscellaneous di-seases, especially acupuncture for spleen-stomach care, are introduced. Based on TCM basic theory and "ten needles for elderly" by WANG Yueting , Professor WANG Yin proposes the acupuncture for spleen-stomach care. In this method, three-element acupoint selection is applied; the conception vessel, spleen meridian of foot taiyin and stomach meridian of foot yangming were selected. The deep and penetration acupuncture with 0.4 mm×100 mm elongated needles is used at Zhongwan (CV 12), Qihai (CV 6) and Zigong (EX-CA 1), and the mild reinforcing-reducing method is used at remaining acupoints. According to the severity of diseases, fire acupuncture combined with blood-letting cupping is applied at Tianshu (ST 25), Xuehai (SP 10) and Yinlingquan (SP 9); gene-rally, two acupoints are selected and 1 to 3 mL blood-letting is appropriate. The modification based on this me-thod can be applied for various difficult and miscellaneous diseases, leading to superior efficacy.

  13. From Wang-Chen System with Only One Stable Equilibrium to a New Chaotic System Without Equilibrium

    Science.gov (United States)

    Pham, Viet-Thanh; Wang, Xiong; Jafari, Sajad; Volos, Christos; Kapitaniak, Tomasz

    2017-06-01

    Wang-Chen system with only one stable equilibrium as well as the coexistence of hidden attractors has attracted increasing interest due to its striking features. In this work, the effect of state feedback on Wang-Chen system is investigated by introducing a further state variable. It is worth noting that a new chaotic system without equilibrium is obtained. We believe that the system is an interesting example to illustrate the conversion of hidden attractors with one stable equilibrium to hidden attractors without equilibrium.

  14. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 85; Issue 6. Issue front cover thumbnail. Volume 85, Issue 6. December 2015, pages 1063-1259u. pp 1063-1072. Rogue wave solutions of the nonlinear Schrödinger eqution with variable coefficients · Changfu Liu Yan Yan Li Meiping Gao Zeping Wang Zhengde Dai ...

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2008-08-13

    Aug 13, 2008 ... Peng-Fei Yin1 2 Li-Li Sun1 3 You-Lu Gao2 Sheng-Yue Wang2. College of Science, Chongqing Jiaotong University, Chongqing 400074, P.R. China; Department of Physics, Southeast University, Nanjing 210096, P.R. China; Department of Physics, Third Military Medical University, Chongqing 400038, P.R. ...

  16. Autocrine and Paracrine Hh Signaling Regulate Prostate Development

    Science.gov (United States)

    2010-09-01

    Rev. Mol. Cell. Biol. 6, 306–317 7. Wang, B. E., Shou, J., Ross, S., Koeppen, H., De Sauvage, F. J., and Gao, W. Q. (2003) J. Biol. Chem. 278, 18506...and Placzek, M. (2006) Nat. Rev. Genet. 7, 841–850 13. Callahan, C. A., Ofstad, T., Horng, L.,Wang, J. K., Zhen, H. H., Coulombe , P. A., and Oro, A. E...Albig, A. R., and Schiemann, W. P. (2005)Mol. Biol. Cell 16, 609–625 45. Olsen, M. W., Ley , C. D., Junker, N., Hansen, A. J., Lund, E. L., and Krist

  17. [Discussion on professor SHAO Jing-Ming's academic opinion of focusing spirit].

    Science.gov (United States)

    Ma, Qiao-Lin; Gao, Xi-Yan; Shao, Su-Ju; Shao, Su-Xia; Hu, Bin

    2014-06-01

    During professor SHAO Jing-ming's academic research and medical practice, his academic opinion of focusing spirit is gradually developed. In terms of nurturing the spirit, attention should be paid on persistence as well as everyday health maintenance and exercise to nurture the spirit of physician. In terms of clinical diagnosis and treatment, patients' psychology, employment and life status should be observed and experienced, which could bring more methods to take essential care of patients' spirit. The treatment should work with psychological counseling, advocating that based on patients' qi and spirit, various forms of treatment methods should be properly used, such as acupuncture or moxibustion or combination of acupuncture and medicine, along with simple acupoint selection and harmony medication. Before clinical treatment of acupuncture, calming the mind is critically emphasized to make a clear diagnosis. During the acupuncture, calming and focusing the mind is necessary as well as emphasizing the details, so acupuncture could be integrated with Chi Gong to create a new warming-sensation technique. In a word, the academic opinion of focusing spirit is shedding an inspiring light upon further study.

  18. [Professor WANG Linpeng's experience of acupuncture for migraine based on different stages and types].

    Science.gov (United States)

    Wang, Shaosong

    2016-07-12

    By using the methods of experience summary and case report, professor WANG Linpeng 's clinical experience of acupuncture for migraine was summarized.Professor WANG proposed the different acupuncture plans should be established according to the active stage and remission stage of migraine; in the active stage acupuncture should be applied at gallbladder meridian with penetration needling technique to reinforce the stimulation intensity; in the remission stage the aim was to regulate zang-fu and back- shu points should be emphasized.In addition, attention should be paid on acupuncture technique and preventive treatment.For menstruation-type and psychological disorder-type migraine, different acupuncture plans should be adopted and regulating meridian and spirit was essential in the treatment.

  19. ADDRESSING THE DEFICIT: Updating the Budgetary Implications of Selected GAO Work

    Science.gov (United States)

    1996-06-01

    DGPS DI DLA DOD DOE DOT DUR EDWAA EM EPA FAIR FAA FAS FDIC FHWA FY GAO GSA HACCP HCFA HHS HMO HUD IDB IFAD INS IRS JCT...Marti, the broadcasts are constantly and effectively jammed , USIA’S research data shows that, mainly as a result of the jamming , the number of Cubans...hours (from 3:30 am to 8:00 am), but Cuban jamming also expanded. In an attempt to overcome jamming , TV Marti has plans to convert from VHF to UHF

  20. Spectrum-effect relationships between high performance liquid ...

    African Journals Online (AJOL)

    promoting effect on contractility of intestinal smooth was carried out to ... addition, the equation of spectrum-effect relationships {Y = 3.818 - 1.126X1 + ..... Peng W, Liu YJ, Wu N, Sun T, He XY, Gao YX, Wu CJ. ... Zheng QF, Zhao YL, Wang JB, Liu TT, Zhang B, Gong ... Zhao HY, Han X. Research thoughts and application.

  1. Yue Joseph Wang named Grant A. Dove Professor of Electrical and Computer Engineering

    OpenAIRE

    Owczarski, Mark

    2009-01-01

    Yue Joseph Wang, professor of electrical and computer engineering in the College of Engineering at Virginia Tech, has been named the Grant A. Dove Professor of Electrical and Computer Engineering by the Virginia Tech Board of Visitors.

  2. Multiple Walkers in the Wang-Landau Algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Brown, G

    2005-12-28

    The mean cost for converging an estimated density of states using the Wang-Landau algorithm is measured for the Ising and Heisenberg models. The cost increases in a power-law fashion with the number of spins, with an exponent near 3 for one-dimensional models, and closer to 2.4 for two-dimensional models. The effect of multiple, simultaneous walkers on the cost is also measured. For the one-dimensional Ising model the cost can increase with the number of walkers for large systems. For both the Ising and Heisenberg models in two-dimensions, no adverse impact on the cost is observed. Thus multiple walkers is a strategy that should scale well in a parallel computing environment for many models of magnetic materials.

  3. Influenza Pandemic: Gaps in Pandemic Planning and Preparedness Need to Be Addressed. Testimony before the Committee on Homeland Security, House of Representatives. GAO-09-909T

    Science.gov (United States)

    Steinhardt, Bernice

    2009-01-01

    As the current H1N1 outbreak underscores, an influenza pandemic remains a real threat to our nation. Over the past 3 years, the US Government Accountability Office (GAO) conducted a body of work, consisting of 12 reports and 4 testimonies, to help the nation better prepare for a possible pandemic. In February 2009, GAO synthesized the results of…

  4. Dynamics analysis of fractional order Yu-Wang system

    Science.gov (United States)

    Bhalekar, Sachin

    2013-10-01

    Fractional order version of a dynamical system introduced by Yu and Wang (Engineering, Technology & Applied Science Research, 2, (2012) 209-215) is discussed in this article. The basic dynamical properties of the system are studied. Minimum effective dimension 0.942329 for the existence of chaos in the proposed system is obtained using the analytical result. For chaos detection, we have calculated maximum Lyapunov exponents for various values of fractional order. Feedback control method is then used to control chaos in the system. Further, the system is synchronized with itself and with fractional order financial system using active control technique. Modified Adams-Bashforth-Moulton algorithm is used for numerical simulations.

  5. Formas retóricas de dizer: o jornalista Celso Ming e seus artigos de opinião

    OpenAIRE

    Santana, Maiara Pereira de

    2015-01-01

    Esta dissertação, produzida na linha Texto e discurso nas modalidades oral e escrita, do Programa de Estudos em Língua Portuguesa da Pontifícia Universidade Católica de São Paulo (PUC-SP), tem por objetivo realizar uma leitura retórica de artigo opinativo, especificamente, o de domínio econômico, escrito pelo jornalista Celso Ming para o jornal O Estado de São Paulo. Para análise, adota-se a perspectiva da retórica, arte e técnica grega, que se atém aos discursos que são passíveis de persuasã...

  6. ‘Unable to think in my mother’s tongue’: immigrant daughters in Alice Pung’s 'Unpolished Gem' and Hsu-Ming Teo’s 'Behind the Moon'

    Directory of Open Access Journals (Sweden)

    Alice Healy

    2010-05-01

    Full Text Available This paper explores ‘the immigrant’s story in translation’ through the various instances of language spoken between parents and children. It analyses the experience of immigrant daughters in two ‘Asian-Australian’ texts – Alice Pung’s recent memoir Unpolished Gem and Hsu-Ming Teo’s Behind the Moon. I position these texts in the context of the reception of literature labelled ‘Asian-Australian’ in the market, exploring Hsu-Ming Teo’s critique of such positioning. Centrally, the paper examines language in all the traditions and moral understandings that language applies, the transformative speech acts between parent and child, and the creative exploration of English as a spectre re-enforcing ‘white nationalism’.The experience of first generation Chinese Australians, in particular Chinese-Singaporeans, Chinese-Malaysians and Chinese-Cambodians, are explored in a reading of this novel and memoir. The point of connection between them is the very different languages between the generations, to the extent that the daughters think in different languages to their mothers, hence a shift in perceiving the world (and society around them.

  7. Nanotubular surface modification of metallic implants via electrochemical anodization technique

    OpenAIRE

    Wang, Lu-Ning; Jin, Ming; Zheng, Yudong; Guan, Yueping; Lu, Xin; Luo, Jing-Li

    2014-01-01

    Lu-Ning Wang,1 Ming Jin,1 Yudong Zheng,1 Yueping Guan,1 Xin Lu,1 Jing-Li Luo21School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, People’s Republic of China; 2Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, CanadaAbstract: Due to increased awareness and interest in the biomedical implant field as a result of an aging population, research in the field of implantable devices has grown rapidly in the...

  8. Symplocaceae

    African Journals Online (AJOL)

    There are only few reports on the chemical composition of ... However, literature searches have shown no report on ..... Jiang J, Feng Z, Wang Y, Zhang P. New phenolics from the roots of ... Song J, Li N, Xia Y, Gao Z, Zou SF, Kong L, Yao YJ, Jiao. YN, Yan YH ... Han YH, Kee JY, Park J, Kim HL, Jeong MY, Kim DS,. Jeon YD ...

  9. The Wang-Landau Sampling Algorithm

    Science.gov (United States)

    Landau, David P.

    2003-03-01

    Over the past several decades Monte Carlo simulations[1] have evolved into a powerful tool for the study of wide-ranging problems in statistical/condensed matter physics. Standard methods sample the probability distribution for the states of the system, usually in the canonical ensemble, and enormous improvements have been made in performance through the implementation of novel algorithms. Nonetheless, difficulties arise near phase transitions, either due to critical slowing down near 2nd order transitions or to metastability near 1st order transitions, thus limiting the applicability of the method. We shall describe a new and different Monte Carlo approach [2] that uses a random walk in energy space to determine the density of states directly. Once the density of states is estimated, all thermodynamic properties can be calculated at all temperatures. This approach can be extended to multi-dimensional parameter spaces and has already found use in classical models of interacting particles including systems with complex energy landscapes, e.g., spin glasses, protein folding models, etc., as well as for quantum models. 1. A Guide to Monte Carlo Simulations in Statistical Physics, D. P. Landau and K. Binder (Cambridge U. Press, Cambridge, 2000). 2. Fugao Wang and D. P. Landau, Phys. Rev. Lett. 86, 2050 (2001); Phys. Rev. E64, 056101-1 (2001).

  10. Prognostic role of microRNA-150 in various carcinomas: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Wang W

    2016-03-01

    Full Text Available Wei Wang, Xinshuai Wang, Yali Zhang, Dan Wang, Hui Gao, Lijuan Wang, Shegan Gao Henan Key Laboratory of Cancer Epigenetics, Cancer Institute, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan, People’s Republic of China Objective: MicroRNA-150 (miR-150 was revealed to be an attractive prognostic biomarker in recent studies. However, the prognostic significance of miR-150 expression in cancer remains inconclusive. The aim of this study was to summarize the global predicting role of miR-150 in survival in patients with various carcinomas.Methods: Eligible studies were identified through multiple search strategies. Data were extracted from the studies by investigating the relationship between miR-150 expression and survival in patients with cancer. A meta-analysis of the hazard ratio (HR was then performed to evaluate the prognostic role of miR-150 in different tumors. Pooled HRs of miR-150 for overall survival and progression-free survival were calculated to measure the effect of miR-150 expression on prognosis.Results: This meta-analysis included nine published studies concerning various carcinomas. Our results indicate that an elevated miR-150 expression is associated with an enhanced overall survival in the digestive tract cancer subgroup (HR =0.57, 95% confidence interval [CI]: 0.37–0.90 and a poor progression-free survival in various cancers (HR =3.08, 95% CI: 2.00–4.75.Conclusion: miR-150 may have the potential to become a new useful prognostic factor to monitor cancer prognosis and progression. However, given the current insufficient relevant data, further clinical studies are needed. Keywords: microRNA-150, carcinomas, prognosis, meta-analysis

  11. Hoisting the Sails, Shining the Bright Pearl——Interviewing LiQingPing, Vice Chairman of the Board of International Pearl Jadeite Jewelry Investment Company, General Manager & CEO of Ming Qin Jewelry Group

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Li Qingping was born in Wuning County, Jiangxi Province, in 1954. Now, he is Vice Chairman of the Board of International Pearl, Jadeite and Jewelry Investment Company, General Manager & CEO of Ming Qin Jewelry Group.

  12. An Interview with Shiang-Kwei Wang: Digital Immigrants versus Digital Natives

    OpenAIRE

    Shaughnessy, Michael F; Kleyn Kennedy, Cynthia Anne

    2015-01-01

    In the field of instructional technology and educational technology, there has always been a discussion about the “great divide“ between digital immigrants and digital natives. Teachers often express exasperation as to the lack of skills that students often possess, and the general consensus that purports that the pupils of today are technologically literate and that their “learning curve” is vastly superior to those of past generations. In this interview, Dr. Shiang-Wei Wang responds to ques...

  13. Multimedia over cognitive radio networks algorithms, protocols, and experiments

    CERN Document Server

    Hu, Fei

    2014-01-01

    PrefaceAbout the EditorsContributorsNetwork Architecture to Support Multimedia over CRNA Management Architecture for Multimedia Communication in Cognitive Radio NetworksAlexandru O. Popescu, Yong Yao, Markus Fiedler , and Adrian P. PopescuPaving a Wider Way for Multimedia over Cognitive Radios: An Overview of Wideband Spectrum Sensing AlgorithmsBashar I. Ahmad, Hongjian Sun, Cong Ling, and Arumugam NallanathanBargaining-Based Spectrum Sharing for Broadband Multimedia Services in Cognitive Radio NetworkYang Yan, Xiang Chen, Xiaofeng Zhong, Ming Zhao, and Jing WangPhysical Layer Mobility Challen

  14. Wang-Landau Reaction Ensemble Method: Simulation of Weak Polyelectrolytes and General Acid-Base Reactions.

    Science.gov (United States)

    Landsgesell, Jonas; Holm, Christian; Smiatek, Jens

    2017-02-14

    We present a novel method for the study of weak polyelectrolytes and general acid-base reactions in molecular dynamics and Monte Carlo simulations. The approach combines the advantages of the reaction ensemble and the Wang-Landau sampling method. Deprotonation and protonation reactions are simulated explicitly with the help of the reaction ensemble method, while the accurate sampling of the corresponding phase space is achieved by the Wang-Landau approach. The combination of both techniques provides a sufficient statistical accuracy such that meaningful estimates for the density of states and the partition sum can be obtained. With regard to these estimates, several thermodynamic observables like the heat capacity or reaction free energies can be calculated. We demonstrate that the computation times for the calculation of titration curves with a high statistical accuracy can be significantly decreased when compared to the original reaction ensemble method. The applicability of our approach is validated by the study of weak polyelectrolytes and their thermodynamic properties.

  15. Becoming an International Scientist in South Korea: Ho Wang Lee’s Research Activity about Epidemic Hemorrhagic Fever

    Directory of Open Access Journals (Sweden)

    Miyoung SHIN

    2017-04-01

    Full Text Available In the 1960-70s, South Korea was still in the position of a science latecomer. Although the scientific research environment in South Korea at that time was insufficient, there was a scientist who achieved outcomes that could be recognized internationally while acting in South Korea. He was Ho Wang Lee(1928~ who found Hantann Virus that causes epidemic hemorrhagic fever for the first time in the world. It became a clue to identify causative viruses of hemorrhagic diseases that were scattered here and there throughout the world. In addition, these outcomes put Ho Wang Lee on the global center of research into epidemic hemorrhagic fever. This paper examines how a Korean scientist who was in the periphery of virology could go into the central area of virology. Also this article shows the process through which the virus found by Ho Wang Lee was registered with the international academia and he proceeded with follow-up research based on this progress to reach the level at which he generalized epidemic hemorrhagic fever related studies throughout the world. While he was conducting the studies, experimental methods that he had never experienced encountered him as new difficulties. He tried to solve the new difficulties faced in his changed status through devices of cooperation and connection. Ho Wang Lee’s growth as a researcher can be seen as well as a view of a researcher that grew from a regional level to an international level and could advance from the area of non-mainstream into the mainstream. This analytic tool is meaningful in that it can be another method of examining the growth process of scientists in South Korea or developing countries.

  16. Higher Education: Actions Needed to Improve Access to Federal Financial Assistance for Homeless and Foster Youth. Report to the Ranking Member, Senate Committee on Health, Education, Labor, and Pensions. GAO-16-343

    Science.gov (United States)

    US Government Accountability Office, 2016

    2016-01-01

    Homeless youth and youth in foster care are often unprepared for the transition to adulthood. Given the economic benefits of college, the Government Accountability Office (GAO) was asked to examine the college experiences of these vulnerable youth. GAO examined: (1) college enrollment and completion for foster and homeless youth; (2) the extent to…

  17. The Chinese Armed Forces in the 21st Century

    Science.gov (United States)

    1999-12-01

    161-162; and Liu Mingtao and Yang Chengjun, Gao jushu zhanzheng zhong de daodan zhan (Missile Wars During High Tech Warfare), Beijing : Guofang daxue ...Guofang daxue chubanshe, 1996; Wang Pufeng, ed., Mao Zedong junshi zhanlue lun {On Mao Zedong’s Military Strategy), Beijing : Junshi kexue chubanshe...Science, Technology and Industry), Beijing : Guofang gongye chubanshe, pp. 157-159; Wu Jianguo, "Gaojishu zhanzheng zhong de he yinying bu rong

  18. Toxicity evaluation of biodegradable chitosan nanoparticles using a zebrafish embryo model

    OpenAIRE

    Hu YL; Qi W; Han F; Shao JZ; Gao JQ

    2011-01-01

    Yu-Lan Hu1, Wang Qi1, Feng Han2, Jian-Zhong Shao3, Jian-Qing Gao11Institute of Pharmaceutics, College of Pharmaceutical Sciences, 2Institute of Pharmacology, Toxicology and Biochemical Pharmaceutics, 3College of Life Sciences, Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaBackground: Although there are a number of reports regarding the toxicity evaluation of inorganic nanoparticles, knowledge on bi...

  19. Security analysis of boolean algebra based on Zhang-Wang digital signature scheme

    International Nuclear Information System (INIS)

    Zheng, Jinbin

    2014-01-01

    In 2005, Zhang and Wang proposed an improvement signature scheme without using one-way hash function and message redundancy. In this paper, we show that this scheme exits potential safety concerns through the analysis of boolean algebra, such as bitwise exclusive-or, and point out that mapping is not one to one between assembly instructions and machine code actually by means of the analysis of the result of the assembly program segment, and which possibly causes safety problems unknown to the software

  20. Security analysis of boolean algebra based on Zhang-Wang digital signature scheme

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Jinbin, E-mail: jbzheng518@163.com [School of Mathematics and Computer Science, Long Yan University, Longyan 364012 (China)

    2014-10-06

    In 2005, Zhang and Wang proposed an improvement signature scheme without using one-way hash function and message redundancy. In this paper, we show that this scheme exits potential safety concerns through the analysis of boolean algebra, such as bitwise exclusive-or, and point out that mapping is not one to one between assembly instructions and machine code actually by means of the analysis of the result of the assembly program segment, and which possibly causes safety problems unknown to the software.

  1. The Taiwanese Perspective in Investigating Korean Confucianism: Lee Ming-huei's Interpretation of Han Wonjin (1682–1750

    Directory of Open Access Journals (Sweden)

    Martina GREIF

    2014-12-01

    Full Text Available Numerous representatives of the contemporary Confucian revival from Taiwan are increasingly demonstrating the fact that the development of Confucian philosophy has to be viewed in a broader cultural context, especially in the context of different East Asian regions. While the development of the Japanese Confucian studies has been elaborated to a great extent during the last decades, studies in Korean Confucianism are still rare. Hence, the present article aims to offer a report on a pioneer contribution in this regard. It introduces Lee Ming-huei’s investigation into the work of one of the most influential Korean Confucians of the Joseon period; on the basis of Huang Chun-chieh’s methodology which exposes the contextualization paradigm, the article explains the main hypotheses and offers a theoretical reflection of the main issues discussed in this research work.

  2. Plant landscape design and its social service function of Shanghai Qibao GaoXian Roof Garden Market

    Directory of Open Access Journals (Sweden)

    Dai Wenbin

    2017-02-01

    Full Text Available With the rapid development of urban social economy,the original green area of the cities has been decreasing continually. In order to meet the humanistic,natural and economic demands of the urban green space,this paper takes the Shanghai Qibao GaoXian Roof Garden Market as an example further studing the social service functions of the market such as leisure meeting,garden life,flower market,education on nature,festival exhibition and so on.

  3. Aviation Safety and Security: Challenges to Implementing the Recommendations of the White House Commission on Aviation Safety and Security -- GAO/T-RCED-97-90

    Science.gov (United States)

    1997-03-05

    This statement before Congress by Gerald L. Dillingham, Associate Director, : Transportation Issues, Resources, Community, and Economic Development Division, : General Accounting Office (GAO) assesses the recommendations contained in the : recently r...

  4. [The innovation of warm disease theory in the Ming Dynasty before Wen yi lun On Pestilence].

    Science.gov (United States)

    Zhang, Zhi-bin

    2008-10-01

    Some doctors of the Ming dynasty raised subversive doubts against the traditional viewpoints of "exogenous cold disease is warm-heat" before the emergence of Wen yi lun (On Pestilence), holding that warm-heat disease "is contracted in different seasons instead of being transformed from cold to warm and/or heat". The conception of the separation of warm-heat disease and exogenous cold disease had changed from obscure to clear. As the idea became clear, the recognition on the new affection of warm, heat, summer-heat, pestilent pathogen was formed, and the idea that the pathogens of summer-heat and warm entered the human body through the mouth and nostrils was put forward. The six-channel syndrome differentiation of warm disease and the five sweat-resolving methods in pestilence raised by the doctors of this period are the aspects of the differential diagnosis of syndrome and treatment in warm diseases, and deserve to be paid attention to.

  5. Review of GAO report on the Nuclear Non-Proliferation Act of 1978. Hearing before the Committee on Foreign Affairs, House of Representatives, Ninety-Seventh Congress, First Session, May 21, 1981

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    Three witnesses from the General Accounting Office (GAO) testified at a May 21, 1981 hearing on the results of a three-year review of the impact and implementation of the Nuclear Non-Proliferation Act (NNPA) of 1978. A total of 115 countries have ratified the Nuclear Non-Proliferation Treaty (NNPT), and some have urged a nuclear-weapons-free zone in Latin America. The GAO proposed recommendations for improving NNPA administration and developing a more coherent long-term policy. The GAO questions the need for additional enrichment capacity, and suggests a closer look at the need to complete the centrifuge facility. It notes only limited progress in multinational fuel-supply assurances and the establishment of international spent-fuel repositories. It urges the US to take a more-active role in these areas and in the international control system. A listing of US exports of highly enriched uranium from 1954 to 1981 follows the testimony

  6. Identity and Friendship in Hsu-Ming Teo´s Behind the Moon (2000

    Directory of Open Access Journals (Sweden)

    Catalina Ribas Segura

    2015-03-01

    Full Text Available In her second novel, Behind the Moon (2000, Hsu-Ming Teo explores the identity construction of three teenage friends and how they defy the notion of the „ideal‟ Australian as a heterosexual, Protestant, white, English-speaking, Australian-born of British ancestry young adult person. Set in the western suburbs of Sydney in the 1990s, the three friends are an example of the multicultural society of the time: Justin Cheong, the son of a Chinese-Singaporean family who arrived in Australia with the Business Migration Programme; Tien Ho, a refugee girl of Chinese-Vietnamese and Afro-CajunCreole-American ancestry; and Nigel „Gibbo‟ Gibson, the son of an Anglo-Australian father and an English mother. The novel tackles different relations among these characters and their families during their teenage years and especially as young adults. This paper seeks to analyse the evolution of the identities of Justin, Tien and „Gibbo‟ through the notions of belonging, gender construction and sexuality. In order to do so, the main theories applied will be the insights on homosexuality and on masculinities of Maria Pallotta-Chiarolli (1995 and Raewyn W. Connell (1995 and Manuel Castellsʼ (2010 identity construction theory

  7. Federal Student Loan Programs: Opportunities Exist to Improve Audit Requirements and Oversight Procedures. Report to Congressional Committees. GAO-10-668

    Science.gov (United States)

    Daly, Kay L.

    2010-01-01

    The Higher Education Opportunity Act of 2008, Pub. L. No. 110-315, mandated GAO (Government Accountability Office) to study the financial and compliance audits and reviews required or conducted for the Federal Family Education Loan (FFEL) program and the Federal Direct Student Loan (DL) program. The Department of Education's (Education) Office of…

  8. Selected papers on noise and stochastic processes

    CERN Document Server

    1954-01-01

    Six classic papers on stochastic process, selected to meet the needs of physicists, applied mathematicians, and engineers. Contents: 1.Chandrasekhar, S.: Stochastic Problems in Physics and Astronomy. 2. Uhlenbeck, G. E. and Ornstein, L. S.: On the Theory of the Browninan Motion. 3. Ming Chen Wang and Uhlenbeck, G. E.: On the Theory of the Browninan Motion II. 4. Rice, S. O.: Mathematical Analysis of Random Noise. 5. Kac, Mark: Random Walk and the Theory of Brownian Motion. 6. Doob, J. L.: The Brownian Movement and Stochastic Equations. Unabridged republication of the Dover reprint (1954). Pre

  9. Nuclear Structure in China 2010

    Science.gov (United States)

    Bai, Hong-Bo; Meng, Jie; Zhao, En-Guang; Zhou, Shan-Gui

    2011-08-01

    fragmentation at the intermediate energy / C. W. Ma ... [et al.].Systematic study of spin assignment and dynamic moment of inertia of high-j intruder band in [symbol]In / K. Y. Ma ... [et al.] -- Signals of diproton emission from the three-body breakup channel of [symbol]Al and [symbol]Mg / Ma Yu-Gang ... [et al.] -- Uncertainties of Th/Eu and Th/Hf chronometers from nucleus masses / Z. M. Niu ... [et al.] -- The chiral doublet bands with [symbol] configuration in A[symbol]100 mass region / B. Qi ... [et al.] -- [symbol] formation probabilities in nuclei and pairing collectivity / Chong Qi -- A theoretical prospective on triggered gamma emission from [symbol]Hf[symbol] isomer / ShuiFa Shen ... [et al.] -- Study of nuclear giant resonances using a Fermi-liquid method / Bao-Xi Sun -- Rotational bands in doubly odd [symbol]Sb / D. P. Sun ... [et al.] -- The study of the neutron N=90 nuclei / W. X. Teng ... [et al.] -- Dynamical modes and mechanisms in ternary reaction of [symbol]Au+[symbol]Au / Jun-Long Tian ... [et al.] -- Dynamical study of X(3872) as a D[symbol] molecular state / B. Wang ... [et al.] -- Super-heavy stability island with a semi-empirical nuclear mass formula / N. Wang ... [et al.] -- Pseudospin partner bands in [symbol]Sb / S. Y. Wang ... [et al.] -- Study of elastic resonance scattering at CIAE / Y. B. Wang ... [et al.] -- Systematic study of survival probability of excited superheavy nuclei / C. J. Xia ... [et al.] -- Angular momentum projection of the Nilsson mean-field plus nearest-orbit pairing interaction model / Ming-Xia Xie ... [et al.] -- Possible shape coexistence for [symbol]Sm in a reflection-asymmetric relativistic mean-field approach / W. Zhang ... [et al.] -- Nuclear pairing reduction due to rotation and blocking / Zhen-Hua Zhang -- Nucleon pair approximation of the shell model: a review and perspective / Y. M. Zhao ... [et al.] -- Band structures in doubly odd [symbol]I / Y. Zheng ... [et al.] -- Lifetimes of high spin states in [symbol]Ag / Y

  10. Recent development in clusters of rare earths and actinides. Chemistry and materials

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Zhiping (ed.) [Arizona Univ., Tucson, AZ (United States). Dept. of Chemistry and Biochemistry

    2017-02-01

    This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

  11. Recent development in clusters of rare earths and actinides. Chemistry and materials

    International Nuclear Information System (INIS)

    Zheng, Zhiping

    2017-01-01

    This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

  12. The Wang-Meng interacting model and the gravitational collapse

    International Nuclear Information System (INIS)

    Campos, Miguel de

    2013-01-01

    Full text: Several alternatives have appear in the literature to supply the accelerated process of universal expansion, and the simplest possibility is to consider the inclusion of a cosmological constant. The inclusion can be realized in both sides of the Einstein field equations, furnishing different physical interpretations in accord with the side of the Einstein field equations where the Λ is added. Considering the inclusion of the cosmological constant in the energy momentum tensor, this additional content is generally interpreted as the energy storage on the vacuum state of all fields in the universe. The inclusion of a vacuum component in the universal fluid furnishes an excellent description of the observed universe, but from the theoretical point of view we do not understand why the vacuum energy is so small and of the same order of magnitude of the matter density (cosmological constant problem). Depending on the point of view of the cosmological constant problem, competing approaches were developed considering a dynamical cosmological 'constant'. A more richer possibility is to consider a non-gravitational interaction models, where the interaction can occur between the dark components, the ordinary matter, and they do not evolve separately. The coupling between dark matter and dark energy has been considered in the literature in a three different ways: dark matter decaying to dark energy; dark energy decaying to dark matter; interacting in both directions. Wang and Meng (CQG 22, 283,2005) considered an alternative to the usual approach for the decay law of the Λ-term assuming the effect of the vacuum in the matter expansion rate. The simple manner adopt by the authors unified several current models that includes a vacuum decaying component interacting with matter content. The vacuum component alters the dynamics of the universal expansion process, then is a natural question: how is the influence of the vacuum energy in the gravitational collapse with a

  13. 消定膏治疗踝关节扭伤的临床观察%Clinical Observation on Treating Ankle Sprain with XiaoDingGao

    Institute of Scientific and Technical Information of China (English)

    王胡伟; 赵道洲; 张磊

    2011-01-01

    目的:观察消定膏外敷治疗踝关节扭伤的疗效.方法:将78名患者随机分为治疗组和对照组,治疗组用消定膏外敷,对照组用七叶皂苷钠凝胶外敷.结果:治疗组有效率为97.4%,对照组有效率为87.2%,2组相比差异有显著性意义(P<0.01).结论:消定膏外敷治疗踝关节扭伤疗效显著,无明显副作用.%Objective:To observe the efficacy of treaing ankle sprains with XiaoDingGao. Method:78 patients were randomly divided into two groups,the treatment group were treated with XiaoDingGao and the control group were treated with escin sodium gel.Result:The effective rate of the treatment group was 97.4%, more superior than the control group (effective rate was 87.2%), the differences between the two groups was significant (P<0.01).Conclusion:Treating ankle sprains with XiaoDingGao has significant effect and no significant side effects, it is worthy of further research and application.

  14. Two alternate proofs of Wang's lune formula for sparse distributed memory and an integral approximation

    Science.gov (United States)

    Jaeckel, Louis A.

    1988-01-01

    In Kanerva's Sparse Distributed Memory, writing to and reading from the memory are done in relation to spheres in an n-dimensional binary vector space. Thus it is important to know how many points are in the intersection of two spheres in this space. Two proofs are given of Wang's formula for spheres of unequal radii, and an integral approximation for the intersection in this case.

  15. ACCORDING TO HWC ON TURKISH WORDS ADOPTED FROM CHINE LANGUAGE / HANYU WAILAICI CIDIAN’a (HWC GÖRE ÇİNCEYE GEÇEN TÜRKÇE KELİMELER ÜZERİNE

    Directory of Open Access Journals (Sweden)

    Prof. Dr. Alimcan İNAYET

    2008-02-01

    Full Text Available Today, there exist thousands of loan words in Chinese language. Chinese linguists -Liu Zheng-yan, Gao Ming-kai, Mai Yong-qian and Shi You-wei- have determined ten thousand loan-words (with the different versions of the same word adopted by Chinese from various languages and published them in “A Dictionary of Loan Words and Hybrid Words in Chinese” in 1984. Among the considered words of this dictionary, there are also hundreds of words which were directly and indirectly adopted from Turkish language and Turkic dialects in various eras. Additionally, some of them are still be in use in Chinese language today. In this article, we have listed those Turkish words determined in this dictionary with the necessary explanations attached.

  16. Eesti ja hiina keel pärinevad ühest allikast : hiina keeleteadlane Gao Jingyi jätkab uurimistööd Eestis / Raimu Hanson

    Index Scriptorium Estoniae

    Hanson, Raimu, 1957-

    2009-01-01

    Hiina keeleteadlane Gao Jingyi on avaldanud raamatu, milles ta näitab, et hiina keel ning eesti keel ja teised läänemeresoome keeled mingil määral koos teiste uurali keeltega pärinevad ühisest allikast

  17. Ning Wang, Making a Market Economy; Yan Sun, Corruption and Market in Contemporary China

    OpenAIRE

    Guiheux, Gilles

    2008-01-01

    These two works shed light on the conditions under which, in the course of the last 25 years, the command economy has been dismantled and gradually replaced by a market system in China . Yan Sun, a professor of political science, is interested in corruption from a double perspective, both at the macro and the micro level. Ning Wang, a neo-institutionalist economist, asks how, thanks to the reforms, a region (Jingzhou, south of Hubei ) has been converted to pisciculture. Corruption is a crucia...

  18. Femtosecond Laser Microstructuring and Chalcogen Inclusion in Silicon

    Science.gov (United States)

    2011-02-12

    photodetectors. The authors would like to acknowledge Dr. Hao Chen, Ariane E. Beck , Dr. Shuling Wang, and Dr. Gauri V. Karve for helpful discussions. This...2002. 3Z. Huang, J. Oh, and J. C. Campbell, Appl. Phys. Lett. 85, 2386 2004. 4Z. Huang, N. Kong, X. Guo, N. Duan, M. Liu, A. L. Beck , S. K...surfaces microstructured in air," Appl. Phys. Lett. 81, 1999-2001 (2002) [doi:10.1063/1.1504868]. [49] S. Tong, X. N. Liu, T. Gao, X. M. Baa , Y

  19. A series solution of the Falkner-Skan equation using the crocco-wang transformation

    Science.gov (United States)

    Asaithambi, Asai

    A direct series solution for the Falkner-Skan equation is obtained by first transforming the problem using the Crocco-Wang transformation. The transformation converts the third-order problem to a second-order two-point boundary value problem. The method first constructs a series involving the unknown skin-friction coefficient α. Then, α is determined by using the secant method or Newton’s method. The derivative needed for Newton’s method is also computed using a series derived from the transformed differential equation. The method is validated by solving the Falkner-Skan equation for several cases reported previously in the literature.

  20. Influenza Pandemic: Continued Focus on the Nation's Planning and Preparedness Efforts Remains Essential. Testimony before the Ad Hoc Subcommittee on State, Local, and Private Sector Preparedness and Integration, Senate Committee on Homeland Security and Governmental Affairs. GAO-09-760T

    Science.gov (United States)

    Steinhardt, Bernice

    2009-01-01

    As the recent outbreak of the H1N1 (swine flu) virus underscores, an influenza pandemic remains a real threat to our nation and to the world. Over the past 3 years, the US Government Accountability Office (GAO) has conducted a body of work to help the nation better prepare for a possible pandemic. In a February 2009 report, GAO synthesized the…

  1. Science, Technology, Engineering, and Mathematics Education: Strategic Planning Needed to Better Manage Overlapping Programs across Multiple Agencies. Report to Congressional Requesters. GAO-12-108

    Science.gov (United States)

    Scott, George A.

    2012-01-01

    Science, technology, engineering, and mathematics (STEM) education programs help to enhance the nation's global competitiveness. Many federal agencies have been involved in administering these programs. Concerns have been raised about the overall effectiveness and efficiency of STEM education programs. GAO examined (1) the number of federal…

  2. Chen-Nester-Tung quasi-local energy and Wang-Yau quasi-local mass

    Science.gov (United States)

    Liu, Jian-Liang; Yu, Chengjie

    2017-10-01

    In this paper, we show that the Chen-Nester-Tung (CNT) quasi-local energy with 4D isometric matching references is closely related to the Wang-Yau (WY) quasi-local energy. As a particular example, we compute the second variation of the CNT quasi-local energy for axially symmetric Kerr-like spacetimes with axially symmetric embeddings at the obvious critical point (0 , 0) and find that it is a saddle critical point in most of the cases. Also, as a byproduct, we generalize a previous result about the coincidence of the CNT quasi-local energy and Brown-York mass for axially symmetric Kerr-like spacetimes by Tam and the first author Liu and Tam (2016) to general spacetimes.

  3. Epidemics in Ming and Qing China: Impacts of changes of climate and economic well-being.

    Science.gov (United States)

    Pei, Qing; Zhang, David D; Li, Guodong; Winterhalder, Bruce; Lee, Harry F

    2015-07-01

    We investigated the mechanism of epidemics with the impacts of climate change and socio-economic fluctuations in the Ming and Qing Dynasties in China (AD 1368-1901). Using long-term and high-quality datasets, this study is the first quantitative research that verifies the 'climate change → economy → epidemics' mechanism in historical China by statistical methods that include correlation analysis, Granger causality analysis, ARX, and Poisson-ARX modeling. The analysis provides the evidences that climate change could only fundamentally lead to the epidemics spread and occurrence, but the depressed economic well-being is the direct trigger of epidemics spread and occurrence at the national and long term scale in historical China. Moreover, statistical modeling shows that economic well-being is more important than population pressure in the mechanism of epidemics. However, population pressure remains a key element in determining the social vulnerability of the epidemics occurrence under climate change. Notably, the findings not only support adaptation theories but also enhance our confidence to address climatic shocks if economic buffering capacity can be promoted steadily. The findings can be a basis for scientists and policymakers in addressing global and regional environmental changes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Raman-scattering results from Y1-xCaxSr2Cu2GaO7

    International Nuclear Information System (INIS)

    Salamon, D.; Liu, R.; Klein, M.V.; Groenke, D.A.; Poeppelmeier, K.R.; Dabrowski, B.; Han, P.D.; Payne, D.A.

    1993-01-01

    We present a Raman-scattering study of Y 1-x Ca x Sr 2 Cu 2 GaO 7 for both the x=0 parent compound and doped compositions with x=0.25 and x=0.40. Extrapolation from YBa 2 Cu 3 O 7-d and other cuprates allows us to assign many of the Raman-active phonon modes in the x=0 material, as well as identify a two-magnon scattering peak, a second-order phonon scattering peak, and a Raman continuum out to 4000 cm -1 . Despite compositional inhomogeneities, the doped superconducting samples show some of the same low-energy phonon features as the x=0 material. There is, however, a doping-dependent shift in the positions of features in the 500--700 cm -1 range, possibly due to Ca locating on Sr sites instead of Y sites. The relative intensities of the phonon peaks in the doped material are also changed from the insulator (x=0), suggesting that a resonant Raman phenomenon is occurring. The temperature-dependent spectra show what appears to be a superconducting dip in the background intensity, but the low superconducting fractions in these samples make this difficult to verify. The doped material also has a Raman continuum out to 4000 cm -1 just as in the x=0 samples, but with the two-magnon and second-order phonon scattering peaks significantly reduced in intensity. This may be a result of changes in the long-range ordering, or another manifestation of the same resonance phenomena occurring at lower energies. Single-crystal samples of the doped material Y 1-x Ca x Sr 2 Cu 2 GaO 7 are necessary for a more conclusive Raman study

  5. Marriages Awakening the World and Shangdong’s Birthday Celebration Custom in Ming and Qing Dynasty%从«醒世姻缘传»看明清山东的寿诞礼俗

    Institute of Scientific and Technical Information of China (English)

    吕文娟; 魏红

    2014-01-01

    Marriages Awakening the World (Xingshi Yinyuan Zhuan )is an important novel aboutMmarriage and family life,published subsequent to J inpingmei Cihua and prior to A Dream of Redansions .Its vivid portrayal of etiquette in the Ming and Qing Dynasties provides bountiful material for the study on life etiquette of that historical period.This thesis makes a systematic probe into the folkways in Shandong reflected in Marriages Awakening the World so as to gain a good understanding of the panorama and characteristics of Shandong folk culture in the Ming and Qing Dynasties.To bemore exact,this study investigates birth- and birthday-celebrating customs in Shandong in detail,un-veiling their underlying cultural meanings.It also delves into the social,cultural and literary Asignificance of the life etiquette in Shandong in the Ming and Qing dynasties reflected in Marriageswakening the World .%«醒世姻缘传»是«金瓶梅词话»之后、«红楼梦»之前的一部重要的以婚姻家庭生活为题材的小说,生动地再现了当时民间礼俗的状态,为我们研究明清时期的人生礼俗提供了宝贵的资料。文章主要探讨该小说与明清山东的寿诞礼俗,分别对诞生礼俗和庆寿礼俗作了详细的描述,并揭示其中所蕴含着的文化意义;对«醒世姻缘传»所反映出的明清山东人生礼俗的社会、文化及文学意义进行阐释。

  6. GAO report and EDF cost revisions reignite debate on Hinkley Point C

    Energy Technology Data Exchange (ETDEWEB)

    Dalton, David [NucNet, The Independent Global Nuclear News Agency, Brussels (Belgium)

    2017-10-15

    The announcement by French state-controlled utility EDF that it has added pound 1.5 bn (Euro 1.7 bn, $ 1.9 bn) to its estimated costs for two new reactors at Hinkley Point C, has led to questions about whether the government should rethink the project, with some politicians calling for it to be abandoned. EDF's announcement came less than two weeks after a report from the Government Accountability Office (GAO) said the government's deal for the two EPR units, now estimated to be costing pound 19.6 bn (Euro 22.3 bn, $ 25.5 bn), has locked consumers into a risky and expensive project with uncertain strategic and economic benefits. The UK's Energy Technologies Institute (ETI), in a report prepared before the EDF announcement, had already said the requirement to improve the predictability and affordability of new nuclear power plants has never been stronger.

  7. GAO report and EDF cost revisions reignite debate on Hinkley Point C

    International Nuclear Information System (INIS)

    Dalton, David

    2017-01-01

    The announcement by French state-controlled utility EDF that it has added pound 1.5 bn (Euro 1.7 bn, $ 1.9 bn) to its estimated costs for two new reactors at Hinkley Point C, has led to questions about whether the government should rethink the project, with some politicians calling for it to be abandoned. EDF's announcement came less than two weeks after a report from the Government Accountability Office (GAO) said the government's deal for the two EPR units, now estimated to be costing pound 19.6 bn (Euro 22.3 bn, $ 25.5 bn), has locked consumers into a risky and expensive project with uncertain strategic and economic benefits. The UK's Energy Technologies Institute (ETI), in a report prepared before the EDF announcement, had already said the requirement to improve the predictability and affordability of new nuclear power plants has never been stronger.

  8. Higher Education: Improved Tax Information Could Help Families Pay for College. Report to the Committee on Finance, U.S. Senate. GAO-12-560

    Science.gov (United States)

    White, James R.; Scott, George A.

    2012-01-01

    The federal government provides billions of dollars in assistance each year to students and families through federal student aid programs authorized under Title IV of the Higher Education Act of 1965 and through tax expenditures, such as credits and deductions. GAO was asked to (1) describe the size and distribution of Title IV student aid and tax…

  9. Influence of yield on in vitro accumulation of aflatoxins in pecan (Carya illinoensis (Wang.) K. Koch) nutmeats.

    Science.gov (United States)

    McMeans, J L

    1983-02-01

    Pecans were harvested from trees (Carya illinoensis (Wang.) K. Koch) in November of 1977 through 1979. Kernel meals from high-, medium-, and low-yielding trees were inoculated with a spore suspension of Aspergillus parasiticus and incubated for 7 days at 25 degrees C. Significant differences in aflatoxin accumulation were found among the three substrates, with a direct correlation between high aflatoxin concentration and tree yield.

  10. Influence of yield on in vitro accumulation of aflatoxins in pecan (Carya illinoensis (Wang.) K. Koch) nutmeats.

    OpenAIRE

    McMeans, J L

    1983-01-01

    Pecans were harvested from trees (Carya illinoensis (Wang.) K. Koch) in November of 1977 through 1979. Kernel meals from high-, medium-, and low-yielding trees were inoculated with a spore suspension of Aspergillus parasiticus and incubated for 7 days at 25 degrees C. Significant differences in aflatoxin accumulation were found among the three substrates, with a direct correlation between high aflatoxin concentration and tree yield.

  11. District of Columbia Opportunity Scholarship Program: Additional Policies and Procedures Would Improve Internal Controls and Program Operations. Report to Congressional Requesters. GAO-08-9

    Science.gov (United States)

    Ashby, Cornelia M.; Franzel, Jeanette M.

    2007-01-01

    The D.C. School Choice Incentive Act created the first private kindergarten-through-grade-12 school-choice program supported by federal funds. The program was named the D.C. Opportunity Scholarship Program (OSP). The United States Government Accountability Office (GAO) was asked to assess the (1) accountability mechanisms governing the use of…

  12. Answer to Wang and Luo, "Polyploidization increases meiotic recombination frequency in Arabidopsis: a close look at statistical modelling and data analysis"

    Directory of Open Access Journals (Sweden)

    Pecinka Ales

    2012-04-01

    Full Text Available Abstract This article is a response to Wang and Luo. See correspondence article http://www.biomedcentral.com/1741-7007/10/30/ [WEBCITE] and the original research article http://www.biomedcentral.com/1741-7007/9/24 [WEBCITE].

  13. An explorative study of the ecological design of residence architecture in Ming and Qing dynasties in Yangzhou

    Directory of Open Access Journals (Sweden)

    Lu Man

    2017-01-01

    Full Text Available Presently ecologicalization has become a key aspect of architecture designs. As studies deepen, the bountiful ecological ideas and design methods represented in Chinese traditional architectural culture are increasingly valued. There remain as of today quite a few residence mansions built in Ming and Qing dynasties in Yangzhou-a city famous for its history and culture. The distinctive regional culture and architectural style that those architectures embody has received worldwide attention in the academic field. By weighing on the shaping of architectural forms, choice in connection genres and structuring measures as well as sorting through and studying on the ecologicalized architectural design practices such as reemploying local materials, deeper understanding of traditional architecture will be achieved for us to better inherit and develop traditional architectural culture. Hence in-depth studies on contemporary ecological architecture and sustainable development will be of greater practical significance. Furthermore, it is beneficial to expand ideas on ecological design, truly integrate architectures into the setting to give expression to the ecological and culture features of them and provide theoretic support for creating new architecture with diversified culture implications and ecological features in light of actual conditions in an orderly manner.

  14. Comments on "Adaptive resolution simulation in equilibrium and beyond" by H. Wang and A. Agarwal

    Science.gov (United States)

    Klein, R.

    2015-09-01

    Wang and Agarwal (Eur. Phys. J. Special Topics, this issue, 2015, doi: 10.1140/epjst/e2015-02411-2) discuss variants of Adaptive Resolution Molecular Dynamics Simulations (AdResS), and their applications. Here we comment on their report, addressing scaling properties of the method, artificial forcings implemented to ensure constant density across the full simulation despite changing thermodynamic properties of the simulated media, the possible relation between an AdResS system on the one hand and a phase transition phenomenon on the other, and peculiarities of the SPC/E water model.

  15. Public health impact of disease-behavior dynamics. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    Science.gov (United States)

    Wells, Chad R.; Galvani, Alison P.

    2015-12-01

    In a loop of dynamic feedback, behavior such as the decision to vaccinate, hand washing, or avoidance influences the progression of the epidemic, yet behavior is driven by the individual's and population's perceived risk of infection during an outbreak. In what we believe will become a seminal paper that stimulates future research as well as an informative teaching aid, Wang et. al. comprehensively review methodological advances that have been used to incorporate human behavior into epidemiological models on the effects of coupling disease transmission and behavior on complex social networks [1]. As illustrated by the recent outbreaks of measles and Middle Eastern Respiratory Syndrome (MERS), here we highlight the importance of coupling behavior and disease transmission that Wang et al. address.

  16. OPTIMIZATION-BASED APPROACH TO TILING OF FINITE AREAS WITH ARBITRARY SETS OF WANG TILES

    Directory of Open Access Journals (Sweden)

    Marek Tyburec

    2017-11-01

    Full Text Available Wang tiles proved to be a convenient tool for the design of aperiodic tilings in computer graphics and in materials engineering. While there are several algorithms for generation of finite-sized tilings, they exploit the specific structure of individual tile sets, which prevents their general usage. In this contribution, we reformulate the NP-complete tiling generation problem as a binary linear program, together with its linear and semidefinite relaxations suitable for the branch and bound method. Finally, we assess the performance of the established formulations on generations of several aperiodic tilings reported in the literature, and conclude that the linear relaxation is better suited for the problem.

  17. [Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu] / Ago Künnap

    Index Scriptorium Estoniae

    Künnap, Ago, 1941-

    2010-01-01

    Arvustus: Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu = Chinese language and languages of northern Europe. Beijing : Zhongguo she hui ke xue chu ban she, 2008

  18. GEOCHEMICAL EXPLORATION

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>20111936 Gao Yuyan(School of Earth Sciences and Resourses,China University of Geosciences,Beijing 100083,China);Wang Mingqi Study on the Geogas Composition of the Concealed Metal Deposit and Its Background Area:Taking Zhangquanzhuang Gold Deposit as an Example(Geological Survey and Research,ISSN1672-4135,CN12-1353/P,33(3),2010,p.198-206,4 illus.,6 tables,10 refs.)Key words:metal ores,geogas methods,Hebei ProvinceStudy on the ore-forming elements,trace elements,REE and their spatial distribution of the geogas in the Zhangquanzhuang gold deposit shows the anomaly compositions o

  19. Comparison of the Wang and Wachsmuth models for π production with measurements at 12 GeV/c

    International Nuclear Information System (INIS)

    Fernow, R.C.

    1996-01-01

    We converted the invariant cross section measurements of Blobel et al. at 12 GeV/c into the form d 2 σ/dΩdp as a function of the LAB total momentum p and p T . We adjusted the parameters of the pion production models of Wang and of Wachsmuth-Hagedorn-Ranft to obtain the best fit to the data. Neither model gave a statistically accurate fit to the data. copyright 1995 American Institute of Physics

  20. A mathematical view for ordinary differential equation models. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Fu, Guifang

    2017-03-01

    Qian Wang et al. have written an interesting article to propose a modeling framework named epiGame in this issue of Physics of Life Reviews [1]. The epiGame framework models how the methylation state of paternal and maternal genomes regulates the embryogenesis as an ecological system in which two highly distinct and specialized gametes coordinate through either cooperation or competition, or both, to maximize the fitness of embryos. Qian Wang et al. also provide solid simulation studies and real data analysis to validate the correctness of their epiGame framework. The importance of embryo development and fertility mechanism cannot be overemphasized, hence, I think that the present review by Qian Wang et al. will stand as a useful modeling guide for practicing biologists or researchers in fertility health to quantify how sperms and oocytes interact through epigenetic process to determine embryo development. In addition, it will serve as a source of many important references to work in the reproductive biology field.

  1. H.E. Professor Wang Liheng, Minister of Aviation of the People's Republic of China, President, China Aerospace Science & Technology Corporation

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    H. E. Professor Wang Liheng, Minister of Aviation, and President, China Aerospace Science & Technology Corporation, People's Republic of China (2nd from left) with (from left to right) Professor Hans Hofer, Professor Roger Cashmore, Research Director for Collider Programmes, Professor Samuel C. C. Ting, CERN and Professor Lei Gang, Secretary to the Minister, September 2001.

  2. Macroscopically constrained Wang-Landau method for systems with multiple order parameters and its application to drawing complex phase diagrams

    Science.gov (United States)

    Chan, C. H.; Brown, G.; Rikvold, P. A.

    2017-05-01

    A generalized approach to Wang-Landau simulations, macroscopically constrained Wang-Landau, is proposed to simulate the density of states of a system with multiple macroscopic order parameters. The method breaks a multidimensional random-walk process in phase space into many separate, one-dimensional random-walk processes in well-defined subspaces. Each of these random walks is constrained to a different set of values of the macroscopic order parameters. When the multivariable density of states is obtained for one set of values of fieldlike model parameters, the density of states for any other values of these parameters can be obtained by a simple transformation of the total system energy. All thermodynamic quantities of the system can then be rapidly calculated at any point in the phase diagram. We demonstrate how to use the multivariable density of states to draw the phase diagram, as well as order-parameter probability distributions at specific phase points, for a model spin-crossover material: an antiferromagnetic Ising model with ferromagnetic long-range interactions. The fieldlike parameters in this model are an effective magnetic field and the strength of the long-range interaction.

  3. Surface adsorption of lattice HP proteins: Thermodynamics and structural transitions using Wang-Landau sampling

    International Nuclear Information System (INIS)

    Li Yingwai; Landau, David P; Wüst, Thomas

    2012-01-01

    Wang-Landau sampling has been applied to investigate the thermodynamics and structural properties of a lattice hydrophobic-polar heteropolymer (the HP protein model) interacting with an attractive substrate. For simplicity, we consider a short HP sequence consisting of only 36 monomers interacting with a substrate which attracts all monomers in the sequence. The conformational “phase transitions” have been identified by a canonical analysis of the specific heat and suitable structural observables. Three major “transitions”, namely, adsorption, hydrophobic core formation and “flattening” of adsorbed structures, are observed. Depending on the surface attractive strength relative to the intra-protein attraction among the H monomers, these processes take place in different sequences upon cooling.

  4. Concentration-dependent effects of fullerenol on cultured hippocampal neuron viability

    Directory of Open Access Journals (Sweden)

    Zha YY

    2012-06-01

    Full Text Available Ying-ying Zha,1 Bo Yang,1 Ming-liang Tang,2 Qiu-chen Guo,1 Ju-tao Chen,1 Long-ping Wen,3 Ming Wang11CAS Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, 2Suzhou Institute of NanoTech and NanoBionics, Chinese Academy of Sciences, Suzhou, 3Laboratory of Nano-biology, School of Life Sciences, University of Science and Technology of China, Hefei, People's Republic of ChinaBackground: Recent studies have shown that the biological actions and toxicity of the water-soluble compound, polyhydroxyfullerene (fullerenol, are related to the concentrations present at a particular site of action. This study investigated the effects of different concentrations of fullerenol on cultured rat hippocampal neurons.Methods and results: Fullerenol at low concentrations significantly enhanced hippocampal neuron viability as tested by MTT assay and Hoechst 33342/propidium iodide double stain detection. At high concentrations, fullerenol induced apoptosis confirmed by Comet assay and assessment of caspase proteins.Conclusion: These findings suggest that fullerenol promotes cell death and protects against cell damage, depending on the concentration present. The concentration-dependent effects of fullerenol were mainly due to its influence on the reduction-oxidation pathway.Keywords: fullerenol, nanomaterial, neurotoxicity, neuroprotection, hippocampal neuron

  5. Interview with Xiaoli Wang PhD winner of CACA 2016 Young Investigator Award

    Directory of Open Access Journals (Sweden)

    Xiaoli Wang

    2016-07-01

    Full Text Available Xiaoli Wang is currently an R&D Senior Scientist in Agilent’s HPLC instrument R&D group at Agilent Technologies, Waldbronn, Germany. Prior to this, he was an R&D manager in Agilent’s CrossLab Group in the US focusing on development of novel chromatographic columns. He has a B.S. degree in Chemistry from Peking University, Beijing China and a PhD. degree in Analytical Chemistry from the University of Minnesota in 2006. He started his industrial career in the pharmaceutical industry at AstraZeneca for four years before joining Agilent Technologies in 2010. Recently, he won the prestigious 2016 Young Investigator Award from Chinese American Chromatography Association (CACA. This interview was conducted by Roland J.W. Meesters PhD, Editor-in-Chief of Journal of Applied Bioanalysis.

  6. Three-dimensional information extraction from GaoFen-1 satellite images for landslide monitoring

    Science.gov (United States)

    Wang, Shixin; Yang, Baolin; Zhou, Yi; Wang, Futao; Zhang, Rui; Zhao, Qing

    2018-05-01

    To more efficiently use GaoFen-1 (GF-1) satellite images for landslide emergency monitoring, a Digital Surface Model (DSM) can be generated from GF-1 across-track stereo image pairs to build a terrain dataset. This study proposes a landslide 3D information extraction method based on the terrain changes of slope objects. The slope objects are mergences of segmented image objects which have similar aspects; and the terrain changes are calculated from the post-disaster Digital Elevation Model (DEM) from GF-1 and the pre-disaster DEM from GDEM V2. A high mountain landslide that occurred in Wenchuan County, Sichuan Province is used to conduct a 3D information extraction test. The extracted total area of the landslide is 22.58 ha; the displaced earth volume is 652,100 m3; and the average sliding direction is 263.83°. The accuracies of them are 0.89, 0.87 and 0.95, respectively. Thus, the proposed method expands the application of GF-1 satellite images to the field of landslide emergency monitoring.

  7. [Comprehension and explanation of meridians and collaterals theory in the background of the spread of western medicine into the East in the Ming and Qing Dynasties].

    Science.gov (United States)

    Li, Su-Yun

    2010-06-01

    In the background of the spread of western medicine into the East in the Ming and Qing Dynasties, Chinese doctors who had accepted western medicine referred to western medical knowledge and began to use the methods of anatomical observation and demonstrating to explain the objective structure of meridians and collaterals. They tried to adopt the artery and vessel explaining the shape of meridian and the blood circle and pulmonary respiration explaining the circulation of Ying-Wei. When the anatomy structures could not perfectly equal to meridians and collaterals, some doctors put forward the gasification feature of meridian to explain the reason. These results suggest that there are difference between meridians and collaterals and pure anatomy concepts, which serves as significant reference and edification for later generations.

  8. Systematic errors due to linear congruential random-number generators with the Swendsen-Wang algorithm: a warning.

    Science.gov (United States)

    Ossola, Giovanni; Sokal, Alan D

    2004-08-01

    We show that linear congruential pseudo-random-number generators can cause systematic errors in Monte Carlo simulations using the Swendsen-Wang algorithm, if the lattice size is a multiple of a very large power of 2 and one random number is used per bond. These systematic errors arise from correlations within a single bond-update half-sweep. The errors can be eliminated (or at least radically reduced) by updating the bonds in a random order or in an aperiodic manner. It also helps to use a generator of large modulus (e.g., 60 or more bits).

  9. Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang’s Article “The Bustle and the Absence of Zhuyi”

    Directory of Open Access Journals (Sweden)

    Aleš Erjavec

    2017-09-01

    Full Text Available The article is a response to the article published in Filozofski vestnik in 2016 and written by Prof. Wanf Jianjiang who in recent years devoted much of his efforts to the influence of of Western aesthetics and philosophy on Chinese humanities. Thus a notion introduced by Prof. Wang Jianjiang – Zhuyi – became the center of discussion in the papers that are to be found in this volume of AM Journal. Prof. Jianjiang claims that Zhuyi has a similar meaning as Western -ism and argues that Chinese aestheticians and intellectuals in general must develop their own theories (-isms if they want to gain speech and not remain stuck with voice (cf. Jacques Rancière.   Article received: May 3, 2017; Article accepted: May 8, 2017; Published online: September 15, 2017 Original scholarly paper How to cite this article: Erjavec, Aleš. "Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang’s Article 'The Bustle and the Absence of Zhuyi'." AM Journal of Art and Media Studies 13 (2017: 111-121. doi: 10.25038/am.v0i13.189

  10. Predictive Control of the Blood Glucose Level in Type I Diabetic Patient Using Delay Differential Equation Wang Model.

    Science.gov (United States)

    Esna-Ashari, Mojgan; Zekri, Maryam; Askari, Masood; Khalili, Noushin

    2017-01-01

    Because of increasing risk of diabetes, the measurement along with control of blood sugar has been of great importance in recent decades. In type I diabetes, because of the lack of insulin secretion, the cells cannot absorb glucose leading to low level of glucose. To control blood glucose (BG), the insulin must be injected to the body. This paper proposes a method for BG level regulation in type I diabetes. The control strategy is based on nonlinear model predictive control. The aim of the proposed controller optimized with genetics algorithms is to measure BG level each time and predict it for the next time interval. This merit causes a less amount of control effort, which is the rate of insulin delivered to the patient body. Consequently, this method can decrease the risk of hypoglycemia, a lethal phenomenon in regulating BG level in diabetes caused by a low BG level. Two delay differential equation models, namely Wang model and Enhanced Wang model, are applied as controller model and plant, respectively. The simulation results exhibit an acceptable performance of the proposed controller in meal disturbance rejection and robustness against parameter changes. As a result, if the nutrition of the person decreases instantly, the hypoglycemia will not happen. Furthermore, comparing this method with other works, it was shown that the new method outperforms previous studies.

  11. United States Merchant Marine Academy: Internal Control Weaknesses Resulted in Improper Sources and Uses of Funds; Some Corrective Actions Are Under Way. Report to Congressional Committees. GAO-09-635

    Science.gov (United States)

    Franzel, Jeanette M.

    2009-01-01

    The U.S. Merchant Marine Academy (Academy), a component of the Department of Transportation's Maritime Administration (MARAD), is one of five U.S. service academies. The Academy is affiliated with 14 nonappropriated fund instrumentalities (NAFI) and two foundations. The US Government Accountability Office (GAO) was asked to determine whether…

  12. A systemic administration of liposomal curcumin inhibits radiation pneumonitis and sensitizes lung carcinoma to radiation

    Directory of Open Access Journals (Sweden)

    Shi HS

    2012-05-01

    Full Text Available Hua-shan Shi1,* Xiang Gao,1,3,* Dan Li,1,* Qiong-wen Zhang,1 Yong-sheng Wang,2 Yu Zheng,1 Lu-Lu Cai,1 Ren-ming Zhong,2 Ao Rui,1 Zhi-yong Li,1 Hao Zheng,1 Xian-cheng Chen,1 Li-juan Chen,11State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medicine School, Sichuan University, Chengdu, Sichuan, People's Republic of China; 2State Key Laboratory of Biotherapy and Department of Thoracic Oncology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China; 3Deparment of Pathophysiology, College of Preclinical and Forensic Medical Sciences, Sichuan University, Chengdu, People's Republic of China*These authors contributed equally to this workAbstract: Radiation pneumonitis (RP is an important dose-limiting toxicity during thoracic radiotherapy. Previous investigations have shown that curcumin is used for the treatment of inflammatory conditions and cancer, suggesting that curcumin may prevent RP and sensitize cancer cells to irradiation. However, the clinical advancement of curcumin is limited by its poor water solubility and low bioavailability after oral administration. Here, a water-soluble liposomal curcumin system was developed to investigate its prevention and sensitizing effects by an intravenous administration manner in mice models. The results showed that liposomal curcumin inhibited nuclear factor-κB pathway and downregulated inflammatory factors including tumor necrosis factor-α, interleukin (IL-6, IL-8, and transforming growth factor-β induced by thoracic irradiation. Furthermore, the combined treatment with liposomal curcumin and radiotherapy increased intratumoral apoptosis and microvessel responses to irradiation in vivo. The significantly enhanced inhibition of tumor growth also was observed in a murine lung carcinoma (LL/2 model. There were no obvious toxicities observed in mice. The current results indicate that liposomal curcumin can effectively

  13. Short communication: Experimental toxocarosis in Chinese Kun Ming mice: Dose-dependent larval distribution and modulation of immune responses.

    Science.gov (United States)

    Ma, Guangxu; Tan, Yancai; Hu, Ling; Luo, Yongfang; Zhu, Honghong; Zhou, Rongqiong

    2015-12-01

    Toxocarosis is an important parasitic zoonosis which is mainly caused by the infective larvae of Toxocara canis. To identify whether there are correlations among the infectious dose, the larval migrans and immune modulation in inbred Chinese Kun Ming (KM) mice, experimental infections were carried out with a range of dosages of 100, 500, 1000, 2000, and 3000 embryonated eggs (EE). Pathogenic reactions were observed in terms of physical and central nervous symptoms. Distributions of T. canis larvae in liver, lung, kidney, heart and brain organs were respectively detected by scanning tissue sections. Moreover, quantitative real-time PCR was employed to identify the variations of Th2 immune response. The results showed that high inocula resulted in advanced larval emergences and arrested migrations in liver, lung, kidney and brain. However, no larvae were found in any of the histological sections of heart tissues. Higher levels of interleukin (IL)-4, IL-5, and IL-10 were detected along with the increasing inoculation doses, but the heaviest inoculum (3000 EE in this study) resulted in the sharp reduction of these ILs. Although no neurological symptoms or mortalities were noticed, these results indicated dose-dependent distribution patterns and immune regulations of T. canis larvae infection in KM mice. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. 2. Sino-German workshop on fuel cells. Book of abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The CD-ROM contains the content of 13 lectures and 19 proposals for joint projects, which were presented on the second Sino-German Workshop on fuel cells. The topics of the 13 lectures are: Ab-initio calculations of oxygen species on low-index platinum surfaces (Pachenko, M.T.M. Koper, T.E. Shubina, S.J. Mitchell, E. Roduner). Cross-Linked (Composite) Polyaryl Blend Membranes for Membrane Fuel Cells. (J.A. Kerres, A. Ullrich, W. Zhang, M. Hein, V. Gogel, L. Joerissen, Th. Frey, A. Friedrich). Performance and Methanol Permeation of Direct Methanol Fuel Cells: Dependence on Operating Conditions and on Electrode Structure(V. Gogel, Th. Frey, K.A. Friedrich, L. Joerissen, J. Garche, Z. Yongsheng). Experimental Investigation of Flow Bed Configuration Effect on Performance of Liquid Feed Direct Methanol Fuel Cells. (H. Guo, C.F. Ma, M.H. Wang, F. Ye, J. Yu, Y. Wang, C.Y. Wang). Improvement of MEAs for DMFC by a tuned production sequence assisted by mathematical modelling (Lindermeir, G. Rosenthal, U. Kunz, U. Hoffmann). Performance of the self-breathing air DMFC with solution grafted PVDF-g-PSSA membranes (X. Qiu, G. Guo, W. Li, W. Zhu, L. Chen). Modeling the Effects of Methanol Crossover on DMFC (J. Zhang, Y. Wang). The characteristics of 40 kW PEM fuel cell engine for vehicle(M. Hou, P. Ming, H. Zhang). A New and Simple Method for Preparing Biocathode in Biofuel Cells (D. Sun, C. Cai, X. Li, W. Xing, T. Lu). Nonlinear Model Reduction of a Dynamic Two-dimensional Molten Carbonate Fuel Cell Model (M. Mangold, M. Sheng). Recent Advances in Design and Fabrication of Low-Temperature Solid Oxide Fuel Cells (C. Xia, G. Meng). Novel CVD Techniques for Micro- and IT-SOFC Fabrication (G. Meng, H. Song, Q. Dong, D. Peng). Fundamental properties of La{sub 0.6}Sr{sub 0.4}Co{sub 0.8}Fe{sub 0.2}O{sub 3-{delta}} at high temperatures (S. Wang, T.-L. Wen).

  15. [Research on Japanese monograph of comprehensive dietetic materia medica, the Pao chu bei yong wo ming ben cao (Japanese Materia Medica Prepared for Kitchen)].

    Science.gov (United States)

    Zhou, M; Ye, J

    2017-11-28

    Japanese physicians of Edo Period (1603-1867) wrote many dietetic books, by combining the knowledge system (content and compiling style) and thoughts of diet therapy from China with local condition in Japan. Among them, the Pao chu bei yong wo ming ben cao ( Japanese Materia Medica Prepared for Kitchen ), written by Mukai Genshou, a physician in the early Edo, is the earliest comprehensive work of dietetic materia medica. In this book, the choice and usage of Japanese dietetic materia medica reveals obvious Japanese local color, including the name, morphology, cultivation, collection, identification, nature and flavor, and indication etc., reflecting the sprouting idea of edible herbal plant at the beginning of Edo period and the characteristic of absorbing Chinese diet thoughts by Japanese physician. This is the important first-hand historical material to understand the development of Japanese dietetic herbalism in early Edo and its dietotherapy culture.

  16. Smoke (Paul Auster et Wayne Wang, 1995 : une œuvre à la croisée des arts

    Directory of Open Access Journals (Sweden)

    Delphine Letort

    2011-04-01

    Full Text Available The adaptation of the short story entitled “Auggie Wren’s Christmas Story” (1990 gathered the writer Paul Auster and the director Wayne Wang around a film project that allowed them to share their artistic practices in a collaborative work. This paper examines the question that underpins the narrative of the short-story by grappling with the appropriations of the real in other artistic modes. Paul Auster’s first encounter with the cinema points out the convergence between aural writing and cinematic writing, evoked through the double figure of the writer and that of the tale-teller/photographer in both the film and the short story.L’adaptation de la nouvelle « Auggie Wren’s Christmas Story » (1990 réunit l’écrivain Paul Auster et le réalisateur Wayne Wang autour d’un projet qui leur permit de croiser leurs pratiques artistiques dans un travail de collaboration. Cet article prolonge le questionnement artistique qui sous-tend le récit de la nouvelle en interrogeant les modalités de l’appropriation du réel par d’autres arts. La première rencontre entre Paul Auster et le cinéma met en relief les points de convergence entre écriture verbale et écriture cinématographique, évoqués autour de la double figure de l’écrivain et du conteur/photographe dans le film et dans la nouvelle.

  17. ¿Cómo podemos usar el móvil para comunicarnos mediante el pensamiento? Entrevista con Yijun Wang

    Directory of Open Access Journals (Sweden)

    Ángel Correa

    2011-01-01

    Full Text Available Un equipo de neurocientíficos ha desarrollado una interfaz cerebro ordenador basada en un teléfono móvil. Las personas con movilidad reducida podrían beneficiarse de este innovador sistema en un futuro próximo. En el experimento que aparece en la fotografía de portada, el participante utiliza únicamente su pensamiento para marcar un número de teléfono. Ciencia Cognitiva ha entrevistado al Dr. Yijun Wang, ingeniero biomédico de la Universidad de California en San Diego, que trabaja en este proyecto.

  18. De Hemingway au chinois classique : le travail de la langue de l’écrivain taïwanais Wang Wen-hsing

    Directory of Open Access Journals (Sweden)

    Sandrine Marchand

    2014-04-01

    Full Text Available Dans les années 1970, l’« occidentalisation » de Wang Wen-hsing lui attire les foudres de la critique. On lui reproche, entre autres choses, de mal écrire, d’être incompréhensible et d’écrire dans une langue occidentalisée. Lui-même semble prendre pour modèle son professeur de français, dont le niveau de chinois classique était très élevé. Entre chinois classique, moderne, dialecte de sa région natale (très proche du dialecte de Taïwan, anglais, et français idéalisé, Wang Wen-hsing invente sa propre langue. Dans les manuscrits de son premier roman, il recourt au syllabaire que les enfants utilisent en cours d’apprentissage de la langue chinoise pour remplacer les caractères d’écriture, syllabaire qui disparaît ensuite à la publication. Que nous apprend l’utilisation de ce syllabaire sur le travail créatif de l’auteur ?Wang Wen-hsing est un auteur qui, entre extrême précision et violence, consacre sa vie et toute son énergie au travail de la langue. Quelle langue tente-t-il d’approcher : le chinois normatif des temps anciens, la langue américaine de Hemingway, ou un mélange des deux ?Multilingue à l’intérieur de la langue chinoise moderne, elle-même langue encore proche du chinois classique, abandonné seulement au début du xxe siècle, l’écriture romanesque de Wang Wen-hsing, qui a pour critère de valeur le « tong-shun » (clarté et aisance, est le fruit de l’oralité et d’une langue expérimentale. Ce rapport à la langue vient-il de sa situation d’émigration, de son isolement des milieux politiques et intellectuels, comme cela lui a été reproché lorsque justement on l’accusait d’écrire dans une langue incompréhensible pour le lecteur ? Pourquoi ces romans sont-ils jugés incompréhensibles ? En raison du niveau du lecteur moyen ? Pour des raisons géopolitiques, car il est un émigré en position dominante dans l’île ? Parce que la langue chinoise est dans

  19. Effects of primary caregiver participation in vestibular rehabilitation for unilateral neglect patients with right hemispheric stroke: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Dai CY

    2013-04-01

    Full Text Available Chin-Ying Dai,1,2 Yu-Hui Huang,3,4 Li-Wei Chou,5,6 Shiao-Chi Wu,7 Ray-Yau Wang,8 Li-Chan Lin9 1School of Nursing, National Yang Ming University, Taipei, Taiwan; 2Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan; 3Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital, Taichung, Taiwan; 4School of Medicine, Chung Shan Medical University, Taichung, Taiwan; 5Department of Physical Medicine and Rehabilitation, China Medical University Hospital, Taichung, Taiwan; 6School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan; 7Institute of Health and Welfare Policy, National Yang-Ming University, Taipei, Taiwan; 8Department of Physical Therapy and Assistive Technology, National Yang-Ming University, Taipei, Taiwan; 9Institute of Clinical and Community Health Nursing, National Yang-Ming University, Taipei, Taiwan, Republic of China Introduction: The current study aims to investigate the effects of primary caregiver participation in vestibular rehabilitation (VR on improving the measures of neglect, activities of daily living (ADL, balance, and falls of unilateral neglect (UN patients. Methods: This study is a single-blind randomized controlled trial. Both experimental (n = 24 and control groups (n = 24 received conventional rehabilitation. The experimental group undertook VR for a month. During the first and second weeks, a registered nurse trained the experimental group in VR. The primary caregivers in the experimental group supervised and guided their patients in VR during the third and fourth weeks. The outcome measures were neglect, ADL, balance, and falls. Results: The two groups of UN patients showed a significant improvement in neglect, ADL, and balance over time. Based on the generalized estimating equations model, an interaction was observed between groups and times. Significant interactions were observed between the VR group

  20. The 2nd International Conference on Agricultural and Biological Sciences (ABS 2016

    Directory of Open Access Journals (Sweden)

    Lei Pei

    2016-10-01

    Salvia of Labiatae in China Xiaojuan Li, Ning Xu, Guofu Zhou, Ming Wan, Qi Lin, Fanyun Meng, Jianxiu Li 15 Three pulling resistance models of pioneer plant in landslide area Yichang Chen, Koayung Yu, Chunpin Chang 16 The comparison of physiological and biochemical mechanisms of Reaumuria soongorica and Salsola passerine in different growth pattern Zijuan Zhou, Peixi Su, Rui Shi, Tingting Xie 17 Resources use efficiency of the cosmopolitan plant Potentilla anserina L. in different alpine habitats in China Rui Shi, Peixi Su, Zijuan Zhou 18 Cloning of PPDK gene from Red Amaranand transformation of Alfalfa Xuelan Liu, Yan Zhang, Xiangfa Wei 19 Variation and cluster analysis of morphological characters and nutrient content of Chucrasia tabularis seed Chong Wu, Yanlei Yin, Lijuan Feng, Xuemei Yang, Fei Wang 20 Effect of the planting density of the areca nut on the growth of intercropped Vanilla Hua Wang, Huifa Zhuang, Zihui Zhu, Hui Wang

  1. Seclusions and Restraints: Selected Cases of Death and Abuse at Public and Private Schools and Treatment Centers. Testimony Before the Committee on Education and Labor, House of Representatives. GAO-09-719T

    Science.gov (United States)

    Kutz, Gregory D.

    2009-01-01

    The Government Accountability Office (GAO) recently testified before the Committee on Education and Labor, House of Representatives, regarding allegations of death and abuse at residential programs for troubled teens. The document presents the statement of Gregory D. Kutz, Managing Director, Forensic Audits and Special Investigations. Recent…

  2. ‘Deconstructing Gao Minglu: critical reflections on contemporaneity and associated exceptionalist readings of contemporary Chinese art’

    Directory of Open Access Journals (Sweden)

    Paul Gladston

    2014-06-01

    Full Text Available In this article, I shall seek to offer an ethically/politically focused critique of exceptionalist accounts of the development of contemporary Chinese art. I shall begin by giving a brief overview of thinking associated with the concept of contemporaneity. I shall then go on to analyze critically an essay by the historian and curator Gao Minglu, which asserts that contemporary Chinese art is open to localized Chinese interpretative perspectives separate from those of internationally dominant postmodernist discourses. In analyzing Gao’s essay, I shall not only argue that its exceptionalist account of the significance of contemporary Chinese art relies on highly selective readings of historical ‘fact’, but also that it is theoretically contradictory/inconsistent and therefore unsustainable as a categorical truth claim. I shall then conclude by examining the ethical/political implications of Gao’s exceptionalist account of the significance of contemporary Chinese art as well as advancing some first thoughts towards a general critique of contemporaneity.

  3. Modifying tetramethyl–nitrophenyl–imidazoline with amino acids: design, synthesis, and 3D-QSAR for improving inflammatory pain therapy

    Directory of Open Access Journals (Sweden)

    Jiang X

    2015-04-01

    Full Text Available Xueyun Jiang,1 Yuji Wang,1 Haimei Zhu,1 Yaonan Wang,1 Ming Zhao,1,2 Shurui Zhao,1 Jianhui Wu,1 Shan Li,1 Shiqi Peng11Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, College of Pharmaceutical Sciences, Capital Medical University, Beijing, People’s Republic of China; 2Faculty of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, TaiwanAbstract: With the help of pharmacophore analysis and docking investigation, 15 novel 1-(4,4,5,5-tetramethyl-2-(3-nitrophenyl-4,5-dihydroimidazol-1-yl-oxyacetyl-L-amino acids (6a–o were designed, synthesized, and assayed. On tail-flick and xylene-induced ear edema models, 10 µmol/kg 6a–o exhibited excellent oral anti-inflammation and analgesic activity. The dose-dependent assay of their representative 6f indicates that the effective dose should be 3.3 µmol/kg. The correlation of the three-dimensional quantitative structure–activity relationship with the docking analysis provides a basis for the rational design of drugs to treat inflammatory pain.Keywords: tetramethylimidazoline, analgesic, anti-inflammatory, 3D-QSAR

  4. New contributions to the knowledge of Chinese flea beetle fauna (III): Revision of Meishania Chen & Wang with description of five new species (Coleoptera: Chrysomelidae: Galerucinae)

    Science.gov (United States)

    The flea beetle genus Meishania Chen & Wang is revised and five new species - M. cangshanensis sp. nov., M. flavipennis sp. nov., M. fulvotigera sp. nov., and M. sichuanica sp. nov. from China and M. bhutanensis sp. nov. from Bhutan - are described. All species of Meishania are illustrated and a key...

  5. Un imaginaire dévoilé/déphasé. Stratégies narratives et mémoire culturelle dans le roman 54 des Wu Ming

    Directory of Open Access Journals (Sweden)

    Matteo Martelli

    2015-02-01

    Full Text Available This essay analyses the narrative strategies through which cultural memory is portrayed in 54, a novel in which Wu Ming (a collective of four Italian fiction writers suggests a literary mapping of the Fifties. This is obtained by a recovery of a shared imaginary tradition which is close to the reader, mixing fictional and historical characters, films, books, different genres of popular literature. Nevertheless, the rewriting of these imaginary traditions involves their displacement, a presentation which is constantly created from an unusual point of view. Thus, shifting the image of what is already known, the text inquires into several modalities of a questioning about cultural memory and its redefinition in relation to contemporary culture. By focusing on these elements, this study proposes an analysis which starts from the construction of the characters, the role of suspense and the adoption of multiple traditions of novel writing.

  6. Grateloupia ramosa Wang & Luan sp. nov. (Halymeniaceae, Rhodophyta), a new species from China based on morphological evidence and comparative rbcL sequences

    Science.gov (United States)

    Cao, Cuicui; Liu, Miao; Guo, Shaoru; Zhao, Dan; Luan, Rixiao; Wang, Hongwei

    2016-03-01

    Grateloupia ramosa Wang & Luan sp. nov. (Halymeniaceae, Rhodophyta) is newly described from Hainan Province, southern China. The organism has the following morphological features: (1) purplish red, cartilaginous and lubricous thalli 5-10 cm in height; (2) compressed percurrent axes bearing abundant branches with opposite arrangement; (3) claw-like apices on top, constricted to 2-4 cm at the base; (4) cortex consisting of 3-6 layers of elliptical or anomalous cells and a medulla covered by compact medullary filaments; (5) reproductive structures distributed throughout the thallus, especially centralized at the bottom of the end portion of the branches; and (6) 4-celled Carpogonial branches and 3-celled auxiliary-cell branches, both of the Grateloupia-type. The morphological diff erences were supported by molecular phylogenetics based on ribulose-1, 5-bisphosphate carboxylase/oxygenase ( rbcL) gene sequence analysis. There was only a 1 bp divergence between specimens collected from Wenchang and Lingshui of Hainan province. The new species was embedded in the large Grateloupia clade of the Halymeniaceae. The pairwise distances between G. ramosa and other species within Grateloupia ranged from 26 to 105 bp, within pairwise distances of 13-111 bp between species of the large genus Grateloupia in Halymeniaceae. Thus, we propose this new species as G. ramosa Wang & Luan sp. nov.

  7. Military Training: Continued Actions Needed to Guide DOD's Efforts to Improve Language Skills and Regional Proficiency. Testimony Before the Subcommittee on Oversight and Investigations, Committee on Armed Services, House of Representatives. GAO-10-879T

    Science.gov (United States)

    Pickup, Sharon L.

    2010-01-01

    Today, and in the foreseeable future, military operations require U.S. personnel to work alongside multinational partners and among local populations. The Department of Defense (DOD) has placed a greater emphasis on transforming language and regional proficiency capabilities, which includes cultural awareness. GAO's prior work has found that…

  8. Guided Image Filtering-Based Pan-Sharpening Method: A Case Study of GaoFen-2 Imagery

    Directory of Open Access Journals (Sweden)

    Yalan Zheng

    2017-12-01

    Full Text Available GaoFen-2 (GF-2 is a civilian optical satellite self-developed by China equipped with both multispectral and panchromatic sensors, and is the first satellite in China with a resolution below 1 m. Because the pan-sharpening methods on GF-2 imagery have not been a focus of previous works, we propose a novel pan-sharpening method based on guided image filtering and compare the performance to state-of-the-art methods on GF-2 images. Guided image filtering was introduced to decompose and transfer the details and structures from the original panchromatic and multispectral bands. Thereafter, an adaptive model that considers the local spectral relationship was designed to properly inject spatial information back into the original spectral bands. Four pairs of GF-2 images acquired from urban, water body, cropland, and forest areas were selected for the experiments. Both quantitative and visual inspections were used for the assessment. The experimental results demonstrated that for GF-2 imagery acquired over different scenes, the proposed approach consistently achieves high spectral fidelity and enhances spatial details, thereby benefitting the potential classification procedures.

  9. HPLC–MS and HPLC–MS/MS analysis of seven active constituents of Xiao-Xu-Ming decoction and application to a pharmacokinetic study after oral administration to rat

    Directory of Open Access Journals (Sweden)

    Yilin Wang

    2012-04-01

    Full Text Available Xiao-xu-ming decoction (XXMD is a traditional Chinese medicine that has been widely used to treat theoplegia and its sequelae. This paper reports the development of three separate assays based on reversed phase high-performance liquid chromatography–mass spectrometry (HPLC–MS and HPLC–MS/MS for the determination of seven active constituents of XXMD viz oroxylin A-7-O-glucuronide, wogonoside, liquiritigenin, cimifugin, 5-O-methylvisammiol, glycyrrhizic acid and glycyrrhetinic acid in rat plasma. All calibration curves were linear (r >0.99 with lower limits of quantitation (LLOQs<12.4 ng/mL. Intra- and inter-day precisions (as relative standard deviation were all <10.7% with recoveries in the range of 88.7–113%. In addition, the seven analytes were shown to be stable in rat plasma samples under relevant storage conditions. The validated methods were successfully applied to a pharmacokinetic study in rat after oral administration of XXMD.

  10. Reply to Comment on ``Effects of fast and slow solar wind on the correlations between interplanetary medium and geomagnetic activity'' by C. B. Wang and J. K. Chao

    Science.gov (United States)

    Ballatore, Paola

    2003-10-01

    The paper [2002] (the paper commented) shows that the statistical significance of the correlations between the interplanetary parameters and the geomagnetic indices (Kp or Dst) is generally less significant during the fastest solar wind. On the other hand, at these fast solar wind periods, the significance of the Kp versus Dst correlation is equal to or higher than during slower solar wind. These results, together with further observations related to substorm periods and with previously published findings, are interpreted in terms of a difference in the interplanetary-magnetospheric coupling for solar wind faster or slower than a certain threshold (identified between about 500 and 600 km/s). Specifically, it is suggested that a possible linear approximation of the geomagnetic-interplanetary coupling is more appropriate during solar wind speed (Vsw) slower than this threshold, being nonlinear processes more dominant during the fastest speeds. This reply highlights that the correlation coefficients shown by [2003] are in agreement with these findings. In addition, Wang and Chao show that the statistical significance of the difference between the correlation coefficients for Vsw ≥ 550 km/s and those for Vsw Wang and Chao is wrong. Moreover, Wang and Chao recalculate the correlations between the interplanetary parameters and the ΔDst instead of Dst; in fact they note that the time derivative of this index (not the index itself) is driven by the interplanetary medium. Here we note that on the contrary, they show that the correlation coefficients between interplanetary parameters and Dst are larger than those obtained using ΔDst and we suggest a possible interpretation in terms of nonlinearity.

  11. All-atom simulation study of protein PTH(1-34) by using the Wang-Landau sampling method

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung-Yeon [Korea National University of Transportation, Chungju (Korea, Republic of); Kwak, Woo-Seop [Chosun University, Gwangju (Korea, Republic of)

    2014-12-15

    We perform simulations of the N-terminal 34-residue protein fragment PTH(1-34), consisting of 581 atoms, of the 84-residue human parathyroid hormone by using the all-atom ECEPP/3 force field and the Wang-Landau sampling method. Through a massive high-performance computation, the density of states and the partition function Z(T), as a continuous function of T, are obtained for PTH(1-34). From the continuous partition function Z(T), the partition function zeros of PTH(1-34) are evaluated for the first time. From both the specific heat and the partition function zeros, two characteristic transition temperatures are obtained for the all-atom protein PTH(1-34). The higher transition temperature T{sub 1} and the lower transition temperature T{sub 2} of PTH(1-34) can be interpreted as the collapse temperature T{sub θ} and the folding temperature T{sub f} , respectively.

  12. A Study of the Documents of the Supervisors of Jingdezhen Imperial Porcelain Factory of Ming and Qing Dynasties%明清时期景德镇御窑厂督陶官的文献考察

    Institute of Scientific and Technical Information of China (English)

    陈宁; 徐波

    2011-01-01

    在景德镇设官监造,宋时已有,元代还成立了专门的官办监陶机构"浮梁磁局"。但是宋元时期监陶官的主要职责是收取地方瓷器生产税,设置目的是为了增加国家财政收入,这与明清时期御窑厂督陶官有很大不同。明清时期,朝廷在景德镇建立御窑厂,专门烧造宫廷用瓷,并委派官员督陶。督陶官作为御窑厂的直接负责人,在御器生产过程中担当着至关重要的角色,对景德镇瓷业乃至中国瓷业的发展有着重要影响。本文通过收集和整理大量的文献史料,对明清时期景德镇御窑厂督陶官及其督陶情况进行了全面梳理和比较分析,使读者对其有一个全面清晰的认识和更为深入的理解,填补了陶瓷史中这部分研究的缺漏。%The practice of assigning porcelain production supervisors in Jingdezhen started from Song Dynasty and Yuan Dynasty saw the founding of a porcelain production watchdog, namely, Fuliang Porcelain Bureau. However, the major responsibility of supervisors of Song and Yuan Dynasties was mainly to collect porcelain production taxes so as to increase the national revenue, which differed greatly from that of supervisors of Ming and Qing dynasties. During Ming and Qing Dynasties, the courts decreed to establish the Impedal Porcelain Factory in Jingdezhen to produce porcelain exclusively for imperial use and to assign supervisors for porcelain production. As the direct managers of the Imperial Porcelain Factory, these supervisors played a vital role in the production of porcelain for imperial use and in the development of the porcelain industry of Jingdezhen and that of China at large. This paper has collected and summarized a great many of documents and made a thorough and comparative analysis of all the supervisors of Ming and Qing Dynasties and their supervision so as to present readers a full, clear and better understanding of this field and to fill the gap of this field in the study

  13. Mutation of a vitelline membrane protein, BmEP80, is responsible for the silkworm "Ming" lethal egg mutant.

    Science.gov (United States)

    Chen, Anli; Gao, Peng; Zhao, Qiaoling; Tang, Shunming; Shen, Xingjia; Zhang, Guozheng; Qiu, Zhiyong; Xia, Dingguo; Huang, Yongping; Xu, Yunmin; He, Ningjia

    2013-02-25

    The egg stage is an important stage in the silkworm (Bombyx mori) life cycle. Normal silkworm eggs are usually short, elliptical, and laterally flattened, with a sometimes hollowed surface on the lateral side. However, the eggs laid by homozygous recessive "Ming" lethal egg mutants (l-e(m)) lose water and become concaved around 1h, ultimately exhibiting a triangular shape on the egg surfaces. We performed positional cloning, and narrowed down the region containing the gene responsible for the l-e(m) mutant to 360 kb on chromosome 10 using 2287 F(2) individuals. Using expression analysis and RNA interference, the best l-e(m) candidate gene was shown to be BmEP80. The results of the inverse polymerase chain reaction showed that an ~1.9 kb region from the 3' untranslated region of BmVMP23 to the forepart of BmEP80 was replaced by a >100 kb DNA fragment in the l-e(m) mutant. Several eggs laid by the normal moths injected with BmEP80 small interfering RNAs were evidently depressed and exhibited a triangular shape on the surface. The phenotype exhibited was consistent with the eggs laid by the l-e(m) mutant. Moreover, two-dimensional gel electrophoresis showed that the BmEP80 protein was expressed in the ovary from the 9th day of the pupa stage to eclosion in the wild-type silkworm, but was absent in the l-e(m) mutant. These results indicate that BmEP80 is responsible for the l-e(m) mutation. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Early-Ming Era tsunami destruction along the Northern Coast of Aceh, Indonesia: New evidence from Archeology

    Science.gov (United States)

    Sieh, K.; Daly, P.; McKinnon, E. E.; Tai, Y. S.; Feener, R. M.; Ishmail, N.

    2017-12-01

    Our colleagues and we have reconstructed partial earthquake and tsunami histories along the coast of Aceh, Sumatra. Chlieh et al (2006) documented and modeled deformation of offshore islands associated with the 2004 rupture. Meltzner et al (2010) found coral evidence of uplifts in 1394±2 and 1450±3 CE. Sieh et al. (2015) documented associated tsunami that destroyed a structure built in 1366±3 CE, 40 km east of Banda Aceh at Lamreh. Since 2015, our landscape archaeology survey of 43 coastal villages over a 40-km reach of the coast has revealed 995 archaeological sites ranging from 10th century to present and containing over 5,000 carved gravestones and 50,000 ceramic sherds. The distribution of ceramic material suggests 7 discrete areas of cultural activity before the 1394 tsunami. Six of these appear to be villages that used imported ceramics and have been populated since the 10th century. However, detailed analysis indicates a clear reduction in activity between 1360 and 1450 CE. This suggests that one or both of the 1394 and 1450 tsunami disrupted the villages. The distribution of post-1500 CE ceramic material shows a gradual repopulation of pre-tsunami sites and a significant expansion of activity starting at the end of the 16th Century, for all areas except Lamreh. Only at on the elevated Lambaro highlands, above modern Lamreh, does material conclusively date between the 1394 and 1450 CE tsunamis. This historic trading site of "Lambri" contains large quantities of ceramics ranging from the early 11th century until the early 16th century, including precisely dated early-Ming (1403-1425 CE) material, some of which is distinctive imperial trade ceramics. We suspect that after the 1394 tsunami destroyed the other coastal settlements, the relatively safe highlands of Lambri were the only areas of the coast utilized for at least 50 years. After about 1450 CE, however, these highlands were abandoned, while the low-lying coastal communities began once again to

  15. GAO's Estimate of the Costs of the "Parental and Medical Leave Act of 1987" (S. 249). Testimony before the Subcommittee on Children, Families, Drugs, and Alcoholism, Committee on Labor and Human Resources, United States Senate.

    Science.gov (United States)

    Gainer, William J.

    The General Accounting Office (GAO) estimates that the cost of S.249, the Parental and Medical Leave Act of 1987, will be, at most, 500 million dollars annually, a figure which reflects the cost of continuing health insurance coverage for employees on unpaid leave. S.249 is legislation which aims to provide to workers at firms with 15 or more…

  16. A Hydrological Tomography Collocated with Time-varying Gravimetry for Hydrogeology -An Example in Yun-Lin Alluvial Plain and Ming-Ju Basin in Taiwan

    Science.gov (United States)

    Chen, K. H.; Cheng, C. C.; Hwang, C.

    2016-12-01

    A new inversion technique featured by the collocation of hydrological modeling and gravimetry observation is presented in this report. Initially this study started from a project attempting to build a sequence of hydrodynamic models of ground water system, which was applied to identify the supplement areas of alluvial plains and basins along the west coast of Taiwan. To calibrate the decent hydro-geological parameters for the modeling, geological evolution were carefully investigated and absolute gravity observations, along with other on-site hydrological monitoring data were specially introduced. It was discovered in the data processing that the time-varying gravimetrical data are highly sensitive to certain boundary conditions in the hydrodynamic model, which are correspondent with respective geological features. A new inversion technique coined by the term "hydrological tomography" is therefore developed by reversing the boundary condition into the unknowns to be solved. An example of accurate estimate for water storage and precipitation infiltration of a costal alluvial plain Yun-Lin is presented. In the mean time, the study of an anticline structure of the upstream basin Ming-Ju is also presented to demonstrate how a geological formation is outlined when the gravimetrical data and hydrodynamic model are re-directed into an inversion.

  17. Estimation of typhoon rainfall in GaoPing River: A Multivariate Maximum Entropy Method

    Science.gov (United States)

    Pei-Jui, Wu; Hwa-Lung, Yu

    2016-04-01

    The heavy rainfall from typhoons is the main factor of the natural disaster in Taiwan, which causes the significant loss of human lives and properties. Statistically average 3.5 typhoons invade Taiwan every year, and the serious typhoon, Morakot in 2009, impacted Taiwan in recorded history. Because the duration, path and intensity of typhoon, also affect the temporal and spatial rainfall type in specific region , finding the characteristics of the typhoon rainfall type is advantageous when we try to estimate the quantity of rainfall. This study developed a rainfall prediction model and can be divided three parts. First, using the EEOF(extended empirical orthogonal function) to classify the typhoon events, and decompose the standard rainfall type of all stations of each typhoon event into the EOF and PC(principal component). So we can classify the typhoon events which vary similarly in temporally and spatially as the similar typhoon types. Next, according to the classification above, we construct the PDF(probability density function) in different space and time by means of using the multivariate maximum entropy from the first to forth moment statistically. Therefore, we can get the probability of each stations of each time. Final we use the BME(Bayesian Maximum Entropy method) to construct the typhoon rainfall prediction model , and to estimate the rainfall for the case of GaoPing river which located in south of Taiwan.This study could be useful for typhoon rainfall predictions in future and suitable to government for the typhoon disaster prevention .

  18. Epigenetic information in gametes: Gaming from before fertilization. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Shi, Junchao; Zhang, Xudong; Liu, Ying; Chen, Qi

    2017-03-01

    In their interesting article [1] Wang et al. proposed a mathematical model based on evolutionary game theory [2] to tackle the fundamental question in embryo development, that how sperm and egg interact with each other, through epigenetic processes, to form a zygote and direct successful embryo development. This work is based on the premise that epigenetic reprogramming (referring to the erasure and reconstruction of epigenetic marks, such as DNA methylation and histone modifications) after fertilization might be of paramount importance to maintain the normal development of embryos, a premise we fully agree, given the compelling experimental evidence reported [3]. Wang et al. have specifically chosen to employ the well-studied DNA methylation reprogramming process during mammalian early embryo development, as a basis to develop their mathematical model, namely epigenetic game theory (epiGame). They concluded that the DNA methylation pattern in mammalian early embryo could be formulated and quantified, and their model can be further used to quantify the interactions, such as competition and/or cooperation of expressed genes that maximize the fitness of embryos. The efforts by Wang et al. in quantitatively and systematically analyzing the beginning of life apparently hold value and represent a novel direction for future embryo development research from both theoretical and experimental biologists. On the other hand, we see their theory still at its infancy, because there are plenty more parameters to consider and there are spaces for debates, such as the cases of haploid embryo development [4]. Here, we briefly comment on the dynamic process of epigenetic reprogramming that goes beyond DNA methylation, a dynamic interplay that involves histone modifications, non-coding RNAs, transposable elements et al., as well as the potential input of the various types of 'hereditary' epigenetic information in the gametes - a game that has started before the fertilization.

  19. Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta): a new species from South China Sea based on morphological observation and rbcL gene sequences analysis.

    Science.gov (United States)

    Yu, Ling; Wang, Hongwei; Luan, Rixiao

    2013-01-01

    Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1) thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2) cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3) the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81-108 bp from the sequences of other samples in Grateloupia; there are 114-133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia.

  20. Entropic sampling of simple polymer models within Wang-Landau algorithm

    International Nuclear Information System (INIS)

    Vorontsov-Velyaminov, P N; Volkov, N A; Yurchenko, A A

    2004-01-01

    In this paper we apply a new simulation technique proposed in Wang and Landau (WL) (2001 Phys. Rev. Lett. 86 2050) to sampling of three-dimensional lattice and continuous models of polymer chains. Distributions obtained by homogeneous (unconditional) random walks are compared with results of entropic sampling (ES) within the WL algorithm. While homogeneous sampling gives reliable results typically in the range of 4-5 orders of magnitude, the WL entropic sampling yields them in the range of 20-30 orders and even larger with comparable computer effort. A combination of homogeneous and WL sampling provides reliable data for events with probabilities down to 10 -35 . For the lattice model we consider both the athermal case (self-avoiding walks, SAWs) and the thermal case when an energy is attributed to each contact between nonbonded monomers in a self-avoiding walk. For short chains the simulation results are checked by comparison with the exact data. In WL calculations for chain lengths up to N = 300 scaling relations for SAWs are well reproduced. In the thermal case distribution over the number of contacts is obtained in the N-range up to N = 100 and the canonical averages - internal energy, heat capacity, excess canonical entropy, mean square end-to-end distance - are calculated as a result in a wide temperature range. The continuous model is studied in the athermal case. By sorting conformations of a continuous phantom freely joined N-bonded chain with a unit bond length over a stochastic variable, the minimum distance between nonbonded beads, we determine the probability distribution for the N-bonded chain with hard sphere monomer units over its diameter a in the complete diameter range, 0 ≤ a ≤ 2, within a single ES run. This distribution provides us with excess specific entropy for a set of diameters a in this range. Calculations were made for chain lengths up to N = 100 and results were extrapolated to N → ∞ for a in the range 0 ≤ a ≤ 1.25

  1. Comment on "Electron impact excitation of N-like ions from the ICFT R-matrix calculation" by HB Wang, G Jiang, XF Li, and ZC He in At. Data Nucl. Data Tables 120 (2018) 373-429

    Science.gov (United States)

    Aggarwal, Kanti M.

    2018-03-01

    The paper "Electron impact excitation of N-like ions from the ICFT R-matrix calculation" by Wang et al. [1] lacks details of calculations, presents only limited data, and has a few anomalies, as listed below.

  2. MicroRNA-142-3p is involved in regulation of MGMT expression in glioblastoma cells

    Directory of Open Access Journals (Sweden)

    Lee YY

    2018-04-01

    Full Text Available Yi-Yen Lee,1,2,* Aliaksandr A Yarmishyn,3,4,* Mong-Lien Wang,3,4 Hsiao-Yun Chen,4,5 Shih-Hwa Chiou,3–5 Yi-Ping Yang,4,5 Chun-Fu Lin,1,2 Pin-I Huang,2,6 Yi-Wei Chen,2,6 Hsin-I Ma,7 Ming-Teh Chen1,2 1Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, 2Faculty of Medicine, National Yang-Ming University, 3Institute of Pharmacology, National Yang-Ming University, 4Department of Medical Research, Taipei Veterans General Hospital, 5Institute of Clinical Medicine, National Yang Ming University, 6Cancer Center, Radiation Oncology Division, Taipei Veterans General Hospital, 7Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan *These authors contributed equally to this work Background: Glioblastoma multiforme (GBM is the most malignant brain tumor, and there is no effective treatment strategy. Patients with GBM have a median overall survival of only 14.6 months. Current treatment consists of safe and maximal surgical excision, followed by concurrent chemoradiotherapy and maintenance chemotherapy. There are several obstacles that hinder the effectiveness of this aggressive treatment. Temozolomide (TMZ is an oral alkylating drug that acts through alkylating the O6 position of guanine in DNA that leads to cell death. However, the expression and enzymatic activity of the DNA repair protein MGMT limits the therapeutic benefit from treatment with TMZ. MGMT reduces the efficacy of alkylating drugs by removing the methyl or alkyl group from damaged O6-methylguanine. Expression levels of MGMT play an important role in the outcome of GBM patients. miRNAs are a group of small regulatory RNAs that control target gene expression by binding to mRNAs. miR-142-3p has been found to be an important factor in the development and maintenance of the oncogenic state. Results: In this study, we sought to investigate whether miR-142-3p can regulate MGMT gene expression in GBM cells

  3. Preclinical evaluation of a urokinase plasminogen activator receptor-targeted nanoprobe in rhesus monkeys

    Directory of Open Access Journals (Sweden)

    Chen Y

    2015-10-01

    Full Text Available Yushu Chen,1 Li Gong,2 Ning Gao,3 Jichun Liao,1 Jiayu Sun,1 Yuqing Wang,1 Lei Wang,1 Pengjin Zhu,1 Qing Fan,1 Yongqiang Andrew Wang,4 Wen Zeng,2 Hui Mao,3 Lily Yang,5 Fabao Gao11Molecular Imaging Center, Department of Radiology, West China Hospital, Sichuan University, Chengdu, 2Sichuan Primed Bio-Tech Group Co, Ltd, Chengdu, People’s Republic of China; 3Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, 4Ocean NanoTech, LLC, San Diego, CA, 5Department of Surgery, Emory University School of Medicine, Atlanta, GA, USAPurpose: To translate a recombinant peptide containing the amino-terminal fragment (ATF of urokinase plasminogen activator receptor-targeted magnetic iron oxide (IO nanoparticles (uPAR-targeted human ATF-IONPs into clinical applications, we conducted a pilot study to evaluate the toxicity and pharmacokinetics of this nanoparticle in normal rhesus monkeys.Methods: We assessed the changes in the following: magnetic resonance imaging (MRI signals from pretreatment stage to 14 days posttreatment, serum iron concentrations from 5 minutes posttreatment to 12 weeks posttreatment, routine blood examination and serum chemistry analysis results from pretreatment stage to 12 weeks after administration, and results of staining of the liver with Perls’ Prussian Blue and hematoxylin–eosin at 24 hours and 3 months posttreatment in two rhesus monkeys following an intravenous administration of the targeted nanoparticles either with a polyethylene glycol (ATF-PEG-IONP or without a PEG (ATF-IONP coating.Results: The levels of alkaline phosphatase, alanine transaminase, and direct bilirubin in the two monkeys increased immediately after the administration of the IONPs but returned to normal within 20 days and stayed within the normal reference range 3 months after the injection. The creatinine levels of the two monkeys stayed within the normal range during the study. In addition, red blood cells

  4. Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta: A New Species from South China Sea Based on Morphological Observation and rbcL Gene Sequences Analysis

    Directory of Open Access Journals (Sweden)

    Ling Yu

    2013-01-01

    Full Text Available Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1 thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2 cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3 the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81–108 bp from the sequences of other samples in Grateloupia; there are 114–133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia.

  5. Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta): A New Species from South China Sea Based on Morphological Observation and rbcL Gene Sequences Analysis

    Science.gov (United States)

    Wang, Hongwei; Luan, Rixiao

    2013-01-01

    Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1) thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2) cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3) the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81–108 bp from the sequences of other samples in Grateloupia; there are 114–133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia. PMID:24455703

  6. Pengaruh insektisida deltametrin terhadap perilaku orientasi parasitoid Anagrus nilaparvatae (Pang et Wang (Hymenoptera: Mymaridae

    Directory of Open Access Journals (Sweden)

    Araz Meilin

    2016-09-01

    Full Text Available Host searching behaviour by a parasitoid includes orientation to the volatile compounds (odor relesead by host or host plant. The aim of this study was to determine the changes in the orientation behaviour of Anagrus nilaparvatae (Pang et Wang, the egg parasitoid of rice brown planthoppers (Nilaparvata lugens (Stål, after being exposed to sublethal concentrations of deltamethrin. The impact of residue on plants to the behaviour of parasitoid was also studied. The sublethal concentrations (LC10 and LC40 used were 0.023 ppm and 2.235 ppm, respectively. Deltamethrin applied to the rice plants were 12.5 ppm and 6.25 ppm, and its effect was observed at 3 hours, 1, 3 and 7 days after application. Orientation behavior was studied using Y-tube olfactometer. Application of deltamethrin at subletal concentration reduced the ability of surviving A. nilaparvatae to detect odors (volatile ompounds released by the host, N. lugens. The higher the concentration of deltamethrin applied to the parasitoid or to the rice plants, the more prominent effect observed in the changing in the parasitoid behavious, in particular disruption to the parasitoid’s orientation to find their host. As consequences, effects of deltamethrin may lead to reduce the effectiveness of A. nilaparvatae as biological control agents in the field as a result of declining their searching capacity. 

  7. PI3K/Akt Pathway Contributes to Neurovascular Unit Protection of Xiao-Xu-Ming Decoction against Focal Cerebral Ischemia and Reperfusion Injury in Rats

    Directory of Open Access Journals (Sweden)

    Rui Lan

    2013-01-01

    Full Text Available In the present study, we used a focal cerebral ischemia and reperfusion rat model to investigate the protective effects of Xiao-Xu-Ming decoction (XXMD on neurovascular unit and to examine the role of PI3K (phosphatidylinositol 3-kinase/Akt pathway in this protection. The cerebral ischemia was induced by 90 min of middle cerebral artery occlusion. Cerebral infarct area was measured by tetrazolium staining, and neurological function was observed at 24 h after reperfusion. DNA fragmentation assay, combined with immunofluorescence, was performed to evaluate apoptosis of neuron, astrocyte, and vascular endothelial cell which constitute neurovascular unit. The expression levels of proteins involved in PI3K/Akt pathway were detected by Western blot. The results showed that XXMD improved neurological function, decreased cerebral infarct area and neuronal damage, and attenuated cellular apoptosis in neurovascular unit, while these effects were abolished by inhibition of PI3K/Akt with LY294002. We also found that XXMD upregulated p-PDKl, p-Akt, and p-GSK3β expression levels, which were partly reversed by LY294002. In addition, the increases of p-PTEN and p-c-Raf expression levels on which LY294002 had no effect were also observed in response to XXMD treatment. The data indicated the protective effects of XXMD on neurovascular unit partly through the activation of PI3K/Akt pathway.

  8. 五鍼刺法원리 및 임상응용에 관한 연구 I 원리에 관한 연구

    Directory of Open Access Journals (Sweden)

    Ahn Chang-beohm

    2008-09-01

    Full Text Available Objective : To review the theoretic basis of the Sa -Ahm 5 Element acupuncture devised about 360 years ago, papers and books were researched. Methods : Total of 59 books and papers ranging from ancient Huang Di nei jing to modern Bio Medical Acupuncture for Pain Management were researched to study the basic theory of it in relation to the 5 Shu points, Results : Gao-mu in Chinese Ming dynasty, for the 1st time, had used 5 Shu points based on creation cycle as tonification and sedation treatment respectively and named it as ‘tonification and sedation treatment of self meridian’ but since then, this method, without special reasons, has been rarely used until Sa -Ahm’s new doctrine that include the concept of destruction cycle was asserted. Conclusions : Sa - Ahm 5 Element acupuncture is a method which uses 5 Shu points from the viewpoints of simultaneous tonification and sedation methods which are based on promotion and control cycles. Though it is nowadays mostly-used method in accordance with practitioner’s points, it needs to be set guidelines by which to effectively practice Sa -Ahm acupuncture.

  9. Migration, Displacement, and Movements in the Global Space: Ming-Yuen S. Ma’s Multi-Media Project Xin Lu: A Travelogue in Four Parts

    Directory of Open Access Journals (Sweden)

    Xiaojing Zhou

    2012-06-01

    Full Text Available In her recent work, Sau-ling Cynthia Wong draws critical attention to the implications of the formation of an Asian American “diaporic community” in cyberspace, where race still operates as an organizing principle of power relations. Although cyberspace is not confined by national borders, Wong examines how subversion of and intervention in race- and sex-based hierarchies in cyberspace can articulate Asian American identities in relation to diasporas and the nation-state. This essay explores the politics of artistic invention in diasporas as embedded in the disruption, dislocation, and fragmentation in Ming-Yuen S. Ma’s multi-media project, Xin Lu: A Travelogue in Four Parts—a series of four experimental videos about Chinese diasporas. It argues that by moving outside the nation-space into the experiential and virtual “global space” of diasporas, Ma’s work addresses Wong’s concerns and enacts a viable “virtual mediation” that situates Chinese diasporas in the historical contexts of British colonialism and American racial exploitation and exclusion. This movement also entails confronting other forms of oppression, including sexism and heterosexism in both the East and West. While giving voice and visibility to the struggles of racial and sexual minorities across national borders, Ma demonstrates the possibilities of a historicized critical approach to diasporas, one which underlies Wong’s insistence in critiquing gendered and racialized power structures both within and outside the nation-state.

  10. Effect of magnetic nanoparticles on apoptosis and cell cycle induced by wogonin in Raji cells

    Directory of Open Access Journals (Sweden)

    Wang XM

    2012-02-01

    Full Text Available Lei Wang1,2,*, Haijun Zhang1,2,*, Baoan Chen1,2, Guohua Xia1,2, Shuai Wang1,2, Jian Cheng1,2, Zeye Shao1,2, Chong Gao1,2, Wen Bao1,2, Liang Tian1,2, Yanyan Ren1,2, Peipei Xu1,2, Xiaohui Cai1,2, Ran Liu1,2, Xuemei Wang3 1Department of Hematology and Oncology, Zhongda Hospital, Medical School, 2Faculty of Oncology, Medical School, 3State Key Laboratory of Bioelectronics (Chien-Shiung Wu Laboratory, Southeast University, Nanjing, China*These authors contributed equally to this workAbstract: Traditional Chinese medicine is gradually becoming a new source of anticancer drugs. One such example is wogonin, which is cytotoxic to various cancer cell lines in vitro. However, due to its low water solubility, wogonin is restricted to clinical administration. Recently, the application of drug-coated magnetic nanoparticles (MNPs to increase water solubility of the drug and to enhance its chemotherapeutic efficiency has attracted much attention. In this study, wogonin was conjugated with the drug delivery system of MNPs by mechanical absorption polymerization to fabricate wogonin-loaded MNPs. It was demonstrated that MNPs could strengthen wogonin-induced cell inhibition, apoptosis, and cell cycle arrest in Raji cells by methylthiazol tetrazolium assay, flow cytometer assay, and nuclear 4',6-diamidino-2-phenylindole staining. Furthermore, the molecular mechanisms of these phenomena were explored by western blot, in which the protein levels of caspase 8 and caspase 3 were increased significantly while those of survivin and cyclin E were decreased significantly in wogonin-MNPs group. These findings suggest that the combination of wogonin and MNPs provides a promising strategy for lymphoma therapy.Keywords: wogonin, magnetic nanoparticles, Raji cell, apoptosis, cell cycle, caspase 8, caspase 3, survivin, cyclin E

  11. Reflection and transmission characteristics of a layer obeying the two-pressure field poroelastic phenomenological model of Berryman and Wang.

    Science.gov (United States)

    Kachkouch, F; Franklin, H; Tinel, A

    2018-07-01

    The characteristics of the reflection and transmission by a fluid-loaded double porosity layer are studied. The medium obeys the two-pressure field poroelastic phenomenological model of Berryman and Wang. The open pore hydraulic conditions applied at the interfaces yield factorized expressions for the coefficients exhibiting on the one hand a separation allowing to distinguish between symmetrical and antisymmetrical motions and on the other hand the way each of the three dilatational waves associate with the shear wave. The numerical study done for a layer of Berea sandstone saturated by water shows clearly the role of each of the dilatational waves. There are peculiarities such as the absence of the fundamental antisymmetrical mode (zero order) and a singular behaviour of the symmetrical fundamental mode. The low frequency approximation for this latter is derived from the proposed formulas and compared with the numerical results. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. Suppression of synaptic plasticity by fullerenol in rat hippocampus in vitro

    Directory of Open Access Journals (Sweden)

    Wang XX

    2016-09-01

    Full Text Available Xin-Xing Wang,1,2,* Ying-Ying Zha,3,* Bo Yang,1 Lin Chen,1,2 Ming Wang1,2 1CAS Key Laboratory of Brain Function and Diseases, 2Auditory Research Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China; 3Cell Electrophysiology Laboratory, Wannan Medical College, Wuhu, Anhui, People’s Republic of China *These authors contributed equally to this work Abstract: Fullerenol, a water-soluble fullerene derivative, has attracted much attention due to its bioactive properties, including the antioxidative properties and free radical scavenging ability. Due to its superior nature, fullerenol represents a promising diagnostic, therapeutic, and protective agent. Therefore, elucidation of the possible side effects of fullerenol is important in determining its potential role. In the present study, we investigated the acute effects of 5 µM fullerenol on synaptic plasticity in hippocampal brain slices of rats. Incubation with fullerenol for 20 minutes significantly decreased the peak of paired-pulse facilitation and long-term potentiation, indicating that fullerenol suppresses the short- and long-term synaptic plasticity of region I of hippocampus. We found that fullerenol depressed the activity and the expression of nitric oxide (NO synthase in hippocampus. In view of the important role of NO in synaptic plasticity, the inhibition of fullerenol on NO synthase may contribute to the suppression of synaptic plasticity. These findings may facilitate the evaluation of the side effects of fullerenol. Keywords: fullerenol, hippocampal slice, nitric oxide synthase, synaptic plasticity, oxidative stress

  13. Nuclear health and safety. Status of GAO's environmental, safety, and health recommendations to DOE

    International Nuclear Information System (INIS)

    England-Joseph, Judy; Bannerman, Carl J.; Fenzel, William F.; Brack, David L.; Harter, Frederick A.

    1990-04-01

    DOE's operations are carried out at many contractor-operated sites around the country, including major sites within the nuclear weapons complex that are involved in the production of nuclear material for weapons and naval fuel. At these sites DOE contractors routinely use and generate large quantities of a wide range of hazardous and radioactive materials. Because these materials require special handling by workers. Also pursuant to Mar. 15, 1989, request, we provided you a report entitled Nuclear Health and Safety: Need for Improved Responsiveness to Problems at DOE Sites (GAO/RCED-90-101, Mar. 28, 1990). to prevent exposure to themselves or releases into the environment, DOE's weapons complex, considered in its entirety, is among the potentially more dangerous industrial operations in the world. Over the last decade, at the request of the Congress, we have carried out a series of assessments and evaluations of various aspects of the complex. In over 60 reports and testimonies published since 1990, we have called attention to the mounting problems facing DOE's nuclear weapons complex. This body of work includes (1) identifying serious, costly, and widespread environmental, safety, and health problems at DOE facilities, (2) calling for outside independent oversight of DOE's nuclear operations, and (3) making recommendations to DOE to strengthen its oversight, providing more detailed information and plans to the Congress, and improving its management and accounting practices. In total, our reports and testimonies have included 54 recommendations to DOE, in addition to recommendations to the Congress, concerning environmental, safety, and health matters at the complex. We consider 23 of the 54 recommendations to be still open. The open recommendations call for improvements such as tighter program controls and clearer standards and policies related to environmental, safety, and health matters

  14. Synchrotron radiation-based multi-analytical approach for studying underglaze color: The microstructure of Chinese Qinghua blue decors (Ming dynasty)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, T. [CEMES, CNRS, Toulouse University, Toulouse (France); Zhu, T.Q., E-mail: zhutq@mail.sysu.edu.cn [School of Sociology and Anthropology of Sun Yat-sen University, Guangzhou (China); Feng, Z.Y. [School of Sociology and Anthropology of Sun Yat-sen University, Guangzhou (China); Fayard, B. [Laboratoire de Physique des Solides, Université Paris-Sud, CNRS – UMR 8502, 91405 Orsay (France); Pouyet, E. [European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38000 Grenoble (France); Cotte, M. [European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38000 Grenoble (France); Sorbonne Universités, UPMC Univ Paris 06, CNRS, UMR 8220, Laboratoire d' archéologie moléculaire et structurale (LAMS), 4 place Jussieu, 75005 Paris (France); De Nolf, W.; Salomé, M. [European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38000 Grenoble (France); Sciau, Ph., E-mail: philippe.sciau@cemes.fr [CEMES, CNRS, Toulouse University, Toulouse (France)

    2016-07-20

    In this paper, we develop a methodological approach combining macro-X-ray fluorescence and synchrotron radiation-based techniques (μXRF, full-field XANES and μXRD) to determine the composition and microstructure of underglaze decors of Qinghua porcelains (Ming dynasty). Various transition metal elements (Fe, Mn, Co) are present in the blue decoration of these ceramics and the approach proposed allows for establishing the feature of each. Thus it shows that Fe ions are distributed homogeneously over the whole glaze without any significant difference in blue and white parts. They do not play a significant role in the color. In contrast, Co ions exhibit a heterogeneous distribution with CoAl{sub 2}O{sub 4} particles close to the body/glaze interphase. These particles play a key role in the blue color and, the hue variations seem in greater part to link to their density and repartition. Co dispersed in the glassy matrix is also bivalent and mainly in tetragonal coordination, leading also to a blue color. Mn ion distribution is similar to the one of Co but without presenting local high concentrations associated to Mn based particles. Mn affects the darkness of the color and for the sample without CoAl{sub 2}O{sub 4} particle; it is the main color contribution. The presence of CoAl{sub 2}O{sub 4} crystals was confirmed by μXRD, which revealed, in addition, a variation of cell parameters certainly linking to a Co partial substitution. - Highlights: • A new methodological approach to describe and determine the underglaze porcelain decors is proposed. • SR-μXRF and FF-XANES allow identifying the speciation of colorant ions and mapping their distribution. • Co in tetragonal coordination is the main cause of blue color of Qinghua porcelains. • The density and the repartition of CoAl{sub 2}O{sub 4} particles define the density of blue color. • Mn ions have an influence on the color darkness.

  15. Passing through the renal clearance barrier: toward ultrasmall sizes with stable ligands for potential clinical applications

    Directory of Open Access Journals (Sweden)

    Zhang XD

    2014-04-01

    Full Text Available Xiao-Dong Zhang,1 Jiang Yang,2 Sha-Sha Song,1 Wei Long,1 Jie Chen,1 Xiu Shen,1 Hao Wang,1 Yuan-Ming Sun,1 Pei-Xun Liu,1 Saijun Fan11Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, People's Republic of China; 2Department of Biological Systems Engineering, University of Wisconsin-Madison, Madison, WI, USAAbstract: The use of nanoparticles holds promise for medical applications, such as X-ray imaging, photothermal therapy and radiotherapy. However, the in vivo toxicity of inorganic nanoparticles raises some concern regarding undesirable side effects which prevent their further medical application. Ultrasmall sub-5.5 nm particles can pass through the barrier for renal clearance, minimizing their toxicity. In this letter we address some recent interesting work regarding in vivo toxicity and renal clearance, and discuss the possible strategy of utilizing ultrasmall nanomaterials. We propose that small hydrodynamic sized nanoclusters can achieve both nontoxic and therapeutic clinical features.Keywords: in vivo clearance, gold nanoparticles, small size

  16. Simple deterministic models and applications. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    Science.gov (United States)

    Yang, Hyun Mo

    2015-12-01

    Currently, discrete modellings are largely accepted due to the access to computers with huge storage capacity and high performance processors and easy implementation of algorithms, allowing to develop and simulate increasingly sophisticated models. Wang et al. [7] present a review of dynamics in complex networks, focusing on the interaction between disease dynamics and human behavioral and social dynamics. By doing an extensive review regarding to the human behavior responding to disease dynamics, the authors briefly describe the complex dynamics found in the literature: well-mixed populations networks, where spatial structure can be neglected, and other networks considering heterogeneity on spatially distributed populations. As controlling mechanisms are implemented, such as social distancing due 'social contagion', quarantine, non-pharmaceutical interventions and vaccination, adaptive behavior can occur in human population, which can be easily taken into account in the dynamics formulated by networked populations.

  17. 王弼《老子注》的詮釋辨證/ Interpretative Dialectics of Wang Bi’s Exegesis of Lao-Tzu

    Directory of Open Access Journals (Sweden)

    Jung-Tao TSAI

    2012-09-01

    Wang Bi, the most prominent scholar of metaphysics of the Wei and Jin Dynasties, was an unprecedented genius throughout the history of Chinese philosophy. In this article, the author examines the brilliant contributions made by Lin Li Zhen, Yu Dun Kang and Rudolf G. Wagner, who are noticed for their research of Exegesis of Lao-Tzu. It is a synthesis of the directions of investigation, approaches, and significant findings they have come up with. Among the three interpretations, Lin focuses on the explanation of Wang’s metaphysic thinking while Yu emphasizes Wang’s secular concerns by proposing the “philosophy of thoroughness” and political holism. As for Wagner, he approaches this work with the views of linguistic philosophy and suggests refined stylistics as interpretative strategy, which functions to enrich the textual contents.

  18. Epigenetic battle of the sexes. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Wu, Song

    2017-03-01

    Qian Wang et al. present an interesting framework, named epigenetic game theory, for modeling sex-based epigenetic dynamics during embryogenesis from a new viewpoint of evolutionary game theory [1]. That is, epigenomes of sperms and oocytes may coordinate through either cooperation or competition, or both, to affect the fitness of embryos. The work uses a set of ordinary differential equations (ODEs) to describe longitudinal trajectories of DNA methylation levels in both parental and maternal gametes and their dependence on each other. The insights gained from this review, i.e. dynamic methylation profiles and their interaction are potentially important to many fields, such as biomedicine and agriculture.

  19. Essays on Korean online game communities: A sense of place: Media and motivation in Korea by the Wang-tta effect; Order and chaos in an ethnography of Korean online game communities

    OpenAIRE

    Chee, Florence

    2005-01-01

    Essay 1 : This paper presents an ethnographic analysis of the different ways Korean game players establish community. I look at Korean PC game rooms as "third places,", and peer relations associated with online video gaming activities. A synthesis of the Korean concept "Wang-tta" and application of the TEDA Ethos protocol provides extra insight into the motivations to excel at digital games and one of the strong drivers of such community membership. Essay 2: This paper explores the dichotomy ...

  20. Terrorism/Criminalogy/Sociology via Magnetism-Hamiltonian ``Models''?!: Black Swans; What Secrets Lie Buried in Magnetism?; ``Magnetism Will Conquer the Universe?''(Charles Middleton, aka ``His Imperial Majesty The Emperior Ming `The Merciless!!!''

    Science.gov (United States)

    Carrott, Anthony; Siegel, Edward Carl-Ludwig; Hoover, John-Edgar; Ness, Elliott

    2013-03-01

    Terrorism/Criminalogy//Sociology : non-Linear applied-mathematician (``nose-to-the grindstone / ``gearheadism'') ''modelers'': Worden,, Short, ...criminologists/counter-terrorists/sociologists confront [SIAM Conf. on Nonlinearity, Seattle(12); Canadian Sociology Conf,. Burnaby(12)]. ``The `Sins' of the Fathers Visited Upon the Sons'': Zeno vs Ising vs Heisenberg vs Stoner vs Hubbard vs Siegel ''SODHM''(But NO Y!!!) vs ...??? Magntism and it turn are themselves confronted BY MAGNETISM,via relatively magnetism/metal-insulator conductivity / percolation-phase-transitions critical-phenomena -illiterate non-linear applied-mathematician (nose-to-the-grindstone/ ``gearheadism'')''modelers''. What Secrets Lie Buried in Magnetism?; ``Magnetism Will Conquer the Universe!!!''[Charles Middleton, aka ``His Imperial Majesty The Emperior Ming `The Merciless!!!']'' magnetism-Hamiltonian phase-transitions percolation-``models''!: Zeno(~2350 BCE) to Peter the Pilgrim(1150) to Gilbert(1600) to Faraday(1815-1820) to Tate (1870-1880) to Ewing(1882) hysteresis to Barkhausen(1885) to Curie(1895)-Weiss(1895) to Ising-Lenz(r-space/Localized-Scalar/ Discrete/1911) to Heisenberg(r-space/localized-vector/discrete/1927) to Priesich(1935) to Stoner (electron/k-space/ itinerant-vector/discrete/39) to Stoner-Wohlfarth (technical-magnetism hysteresis /r-space/ itinerant-vector/ discrete/48) to Hubbard-Longuet-Higgins (k-space versus r-space/

  1. The negative cell cycle regulator, Tob (transducer of ErbB-2), is involved in motor skill learning

    International Nuclear Information System (INIS)

    Wang Xinming; Gao Xiang; Zhang Xuehan; Tu Yanyang; Jin Meilei; Zhao Guoping; Yu Lei; Jing Naihe; Li Baoming

    2006-01-01

    Tob (transducer of ErbB-2) is a negative cell cycle regulator with anti-proliferative activity in peripheral tissues. Our previous study identified Tob as a protein involved in hippocampus-dependent memory consolidation (M.L. Jin, X.M. Wang, Y.Y. Tu, X.H. Zhang, X. Gao, N. Guo, Z.Q. Xie, G.P. Zhao, N.H. Jing, B.M. Li, Y.Yu, The negative cell cycle regulator, Tob (Transducer of ErbB-2), is a multifunctional protein involved in hippocampus-dependent learning and memory, Neuroscience 131 (2005) 647-659). Here, we provide evidence that Tob in the central nervous system is engaged in acquisition of motor skill. Tob has a relatively high expression in the cerebellum. Tob expression is up-regulated in the cerebellum after rats receive training on a rotarod-running task. Rats infused with Tob antisense oligonucleotides into the 4th ventricle exhibit a severe deficit in running on a rotating rod or walking across a horizontally elevated beam

  2. Iron oxide magnetic nanoparticles combined with actein suppress non-small-cell lung cancer growth in a p53-dependent manner

    Directory of Open Access Journals (Sweden)

    Wang MS

    2017-10-01

    Full Text Available Ming-Shan Wang,1 Liang Chen,2 Ya-Qiong Xiong,2 Jing Xu,2 Ji-Peng Wang,2 Zi-Li Meng2 1Department of Oncology, Huaiyin Hospital of Huai’an City, Huai’an, China; 2Department of Respiration, Huai’an First People’s Hospital, Nanjing Medical University, Huai’an, China Abstract: Actein (AT is a triterpene glycoside isolated from the rhizomes of Cimicifuga foetida that has been investigated for its antitumor effects. AT treatment leads to apoptosis in various cell types, including breast cancer cells, by regulating different signaling pathways. Iron oxide (Fe3O4 magnetic nanoparticles (MNPs are nanomaterials with biocompatible activity and low toxicity. In the present study, the possible benefits of AT in combination with MNPs on non-small-cell lung cancer (NSCLC were explored in in vitro and in vivo studies. AT-MNP treatment contributed to apoptosis in NSCLC cells, as evidenced by activation of the caspase 3-signaling pathway, which was accompanied by downregulation of the antiapoptotic proteins Bcl2 and BclXL, and upregulation of the proapoptotic signals Bax and Bad. The death receptors of TRAIL were also elevated following AT-MNP treatment in a p53-dependent manner. Furthermore, a mouse xenograft model in vivo revealed that AT-MNP treatment exhibited no toxicity and suppressed NSCLC growth compared to either AT or MNP monotherapies. In conclusion, this study suggests a novel therapy to induce apoptosis in suppressing NSCLC growth in a p53-dependent manner by combining AT with Fe3O4 MNPs. Keywords: actein, Fe3O4 magnetic nanoparticles, NSCLC, apoptosis, p53

  3. Effects of surface charges of gold nanoclusters on long-term in vivo biodistribution, toxicity, and cancer radiation therapy

    Directory of Open Access Journals (Sweden)

    Wang JY

    2016-07-01

    Full Text Available Jun-Ying Wang,1 Jie Chen,1 Jiang Yang,2 Hao Wang,1 Xiu Shen,1 Yuan-Ming Sun,1 Meili Guo,3 Xiao-Dong Zhang4 1Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 2Environment, Energy and Natural Resources Center, Department of Environmental Science and Engineering, Fudan University, Shanghai, 3Department of Physics, School of Science, Tianjin Chengjian University, 4Department of Physics, School of Science, Tianjin University, Tianjin, People’s Republic of China Abstract: Gold nanoclusters (Au NCs have exhibited great advantages in medical diagnostics and therapies due to their efficient renal clearance and high tumor uptake. The in vivo effects of the surface chemistry of Au NCs are important for the development of both nanobiological interfaces and potential clinical contrast reagents, but these properties are yet to be fully investigated. In this study, we prepared glutathione-protected Au NCs of a similar hydrodynamic size but with three different surface charges: positive, negative, and neutral. Their in vivo biodistribution, excretion, and toxicity were investigated over a 90-day period, and tumor uptake and potential application to radiation therapy were also evaluated. The results showed that the surface charge greatly influenced pharmacokinetics, particularly renal excretion and accumulation in kidney, liver, spleen, and testis. Negatively charged Au NCs displayed lower excretion and increased tumor uptake, indicating a potential for NC-based therapeutics, whereas positively charged clusters caused transient side effects on the peripheral blood system. Keywords: gold clusters, in vivo toxicity, long-term, cancer therapy

  4. 明代朝鲜使臣与辽东百姓交往研究%The Research Of Communications Between Korean Envoys And Liaodong People In Ming Dynasty

    Institute of Scientific and Technical Information of China (English)

    刘春丽

    2012-01-01

    Liaodong was the only way which must be passed for Korean Envoys to pay tribute to Ming Dynasty by land route.When Korean Envoys passed through,both Korean Envoys and Liaodong people grasped the friendly attitudes.However,misunderstandings and unfriendly behaviors occurred occasionally.This article shows communications between Korean Envoys and Liaodong people, which may help us to know more about the relationship history of Northeast China and Korean.%明代辽东是朝鲜使臣陆路进贡明朝的必经之路,朝鲜使臣行经辽东过程中,频频接触辽东百姓。朝鲜使臣与辽东百姓交往的过程中,双方都能秉持友好态度,友好交往是主旋律,但也存在着误读和不友好行为。对此,梳理朝鲜使臣与辽东百姓交往情况,以期有助于中国东北与朝鲜关系史的研究。同时,对当今的中朝、中韩两国人民间的交往有一定的现实借鉴意义。

  5. Witnessing Solar Rejuvenation

    Science.gov (United States)

    Kohler, Susanna

    2015-09-01

    At the end of last year, the Suns large-scale magnetic field suddenly strengthened, reaching its highest value in over two decades. Here, Neil Sheeley and Yi-Ming Wang (both of the Naval Research Laboratory) propose an explanation for why this happened and what it predicts for the next solar cycle.Magnetic StrengtheningUntil midway through 2014, solar cycle 24 the current solar cycle was remarkably quiet. Even at its peak, it averaged only 79 sunspots per year, compared to maximums of up to 190 in recent cycles. Thus it was rather surprising when, toward the end of 2014, the Suns large-scale magnetic field underwent a sudden rejuvenation, with its mean field leaping up to its highest values since 1991 and causing unprecedentedly large numbers of coronal loops to collapse inward.Yet in spite of the increase we observed in the Suns open flux (the magnetic flux leaving the Suns atmosphere, measured from Earth), there was not a significant increase in solar activity, as indicated by sunspot number and the rate of coronal mass ejections. This means that the number of sources of magnetic flux didnt increase so Sheeley and Wang conclude that flux must instead have been emerging from those sources in a more efficient way! But how?Aligned ActivityWSO open flux and the radial component of the interplanetary magnetic field (measures of the magnetic flux leaving the Suns photosphere and heliosphere, respectively), compared to sunspot number (in units of 100 sunspots). A sudden increase in flux is visible after the peak of each of the last four sunspot cycles. Click for a larger view! [Sheeley Wang 2015]The authors show that the active regions on the solar surface in late 2014 lined up in such a way that the emerging flux was enhanced, forming a strong equatorial dipole field that accounts for the sudden rejuvenation observed.Interestingly, this rejuvenation of the Suns open flux wasnt just a one-time thing; similar bursts have occurred shortly after the peak of every sunspot

  6. Risky choice with heuristics: reply to Birnbaum (2008), Johnson, Schulte-Mecklenbeck, and Willemsen (2008), and Rieger and Wang (2008).

    Science.gov (United States)

    Brandstätter, Eduard; Gigerenzer, Gerd; Hertwig, Ralph

    2008-01-01

    E. Brandstätter, G. Gigerenzer, and R. Hertwig (2006) showed that the priority heuristic matches or outperforms modifications of expected utility theory in predicting choice in 4 diverse problem sets. M. H. Birnbaum (2008) argued that sets exist in which the opposite is true. The authors agree--but stress that all choice strategies have regions of good and bad performance. The accuracy of various strategies systematically depends on choice difficulty, which the authors consider a triggering variable underlying strategy selection. Agreeing with E. J. Johnson, M. Schulte-Mecklenbeck, and M. C. Willemsen (2008) that process (not "as-if") models need to be formulated, the authors show how quantitative predictions can be derived and test them. Finally, they demonstrate that many of Birnbaum's and M. O. Rieger and M. Wang's (2008) case studies championing their preferred models involved biased tests in which the priority heuristic predicted data, whereas the parameterized models were fitted to the same data. The authors propose an adaptive toolbox approach of risky choice, according to which people first seek a no-conflict solution before resorting to conflict-resolving strategies such as the priority heuristic. (c) 2008 APA, all rights reserved

  7. Measuring and Reporting Leadership and Core Competency Domains

    Science.gov (United States)

    2015-09-04

    Management : Defense’s System for Army Military Payroll Is Unreliable,” GAO-93-32 (Washington, D.C.: GAO, September 30, 1993). 7 GAO, “DoD Systems...Deficiencies in Controls over Army Active Duty Military Payroll ,” GAO-13-28, (Washington, D.C.: GAO, December 2012); GAO, “DOD Financial Management : The...culture, regional/technical, and leadership/influence.   Examining the numerous military personnel information management systems across DoD, IDA found

  8. Clinical significance of promoter region hypermethylation of microRNA-148a in gastrointestinal cancers

    Directory of Open Access Journals (Sweden)

    Sun JX

    2014-05-01

    Full Text Available Jingxu Sun,1,* Yongxi Song,1,* Zhenning Wang,1 Guoli Wang,2 Peng Gao,1 Xiaowan Chen,1 Zhaohua Gao,1 Huimian Xu1 1Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Biochemistry and Molecular Biology, China Medical University, Shenyang, People’s Republic of China *These authors contributed equally to this work Background: MicroRNAs are associated with tumor genesis and progression in various carcinomas. MicroRNA-148a (miR-148a was reported to have low expression in gastrointestinal cancers, and might be regulated by promoter region DNA methylation. Methods: Bisulfite-modified sequencing was used to determine the promoter region DNA methylation status of human gastrointestinal cancer cell lines. Expression levels of miR-148a in cell lines treated with 5-aza-2′-deoxycytidine were determined by quantitative real-time polymerase chain reaction. Total DNA was extracted from the tissues of 64 patients with gastric cancer and 51 patients with colorectal cancer. Methylation status was determined by methylation-specific polymerase chain reaction. All statistical analyses were performed with SPSS 17.0 software. Results: The promoter regions of genes in human gastrointestinal cancer cell lines were all hypermethylated, except for HT-29, and the expression of miR-148a tended to be higher than in controls after treatment with 5-aza-2′-deoxycytidine. The methylation-specific polymerase chain reaction results showed that 56.25% of gastric cancer tissues and 19.61% of colorectal cancer tissues were hypermethylated. A strong correlation was found between the expression of miR-148a and the methylation status of promoter regions (P<0.001, chi-square test and Pearson’s correlation. Furthermore, promoter region CpG site hypermethylation of miR-148a was correlated with increased tumor size (P=0.01 in gastric cancer after analyzing the correlation between

  9. Principal Component Analysis of Chinese Porcelains from the Five Dynasties to the Qing Dynasty

    Science.gov (United States)

    Yap, C. T.; Hua, Younan

    1992-10-01

    This is a study of the possibility of identifying antique Chinese porcelains according to the period or dynasty, using major and minor chemical components (SiO2 , Al2O3 , Fe2O3 , K2O, Na2O, CaO and MgO) from the body of the porcelain. Principal component analysis is applied to published data on 66 pieces of Chinese procelains made in Jingdezhen during the Five Dynasties and the Song, Yuan, Ming and Qing Dynasties. It is shown that porcelains made during the Five Dynasties and the Yuan (or Ming) and Qing Dynasties can be segregated completely without any overlap. However, there is appreciable overlap between the Five Dynasties and the Song Dynasty, some overlap between the Song and Ming Dynasties and also between the Yuan and Ming Dynasties. Interestingly, Qing procelains are well separated from all the others. The percentage of silica in the porcelain body decreases and that of alumina increases with recentness with the exception of the Yuan and Ming Dynasties, where this trend is reversed.

  10. A new concept: Epigenetic game theory. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Zheng, Xiu-Deng; Tao, Yi

    2017-03-01

    The evolutionary significance of the interaction between paternal and maternal genomes in fertilized zygotes is a very interesting and challenging question. Wang et al. developed the concept of epigenetic game theory, and they try to use this concept to explain the interaction between paternal and maternal genomes in fertilized zygotes [1]. They emphasize that the embryogenesis can be considered as an ecological system in which two highly distinct and specialized gametes coordinate through either cooperation or competition, or both, to maximize the fitness of embryos under Darwinian selection. More specifically, they integrate game theory to model the pattern of coordination of paternal genome and maternal genomes mediated by DNA methylation dynamics, and they called this epigenetic game theory.

  11. 王友仁点穴开合按动法针对踝关节扭伤推拿经验浅析%Discussion on WANG You-ren's Treatment for Sprain of Ankle with Andong Therapy of Pressing Acupoint Combined with Joint Switching

    Institute of Scientific and Technical Information of China (English)

    包庆旭

    2017-01-01

    This article focused on WANG You-ren chief physician's Andong therapy theory system, systematically summarized the treatment ideas and characteristics of acute phase for the sprain of ankle. Combined with typical cases, details of WANG You-ren chief physician's treatment with specific press method, remote press method, holographic press method, and corresponding to the press method for the acupoints principle were introduced. WANG You-ren chief physician also proposed early treatment and active protection when people have sprain of ankle, with a purpose to achieve the good efficacy, such as relieve acute pain, reduce swelling, and few sequelae.%本文重点对王友仁主任医师以按动疗法理论体系为纲要,对踝关节扭伤急性期的治疗思路和特色手法进行系统总结,并结合典型病例,详细介绍王友仁主任医师用特定按动法、远端按动法、全息按动法、对应按动法为取穴原则,以达到点穴镇痛在先、开合按动顺筋归位在后的推拿治疗方法.王友仁主任医师提出踝关节扭伤后应及早治疗、积极防护,达到急者镇痛、消肿,缓者后遗症少的理念,在临床上获得满意疗效.

  12. Мао без головы / Мэлор Стуруа

    Index Scriptorium Estoniae

    Стуруа, Мэлор, 1928-

    2010-01-01

    Hiina skulptoritest Gao Zhenist ja Gao Qiangist, kes esinevad kunstnikunime Gao Vennad (Gao Brothers) all. Vendade dissidentlikust loomingust, nende skulptuurist "Mao süü" (Mao's Guilt), mis kujutab diktaator Mao Zedongi põlvili ja eemaldatava-külgekruvitava peaga

  13. Using game theory to investigate the epigenetic control mechanisms of embryo development: Comment on: "Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition" by Qian Wang et al.

    Science.gov (United States)

    Zhang, Le; Zhang, Shaoxiang

    2017-03-01

    A body of research [1-7] has already shown that epigenetic reprogramming plays a critical role in maintaining the normal development of embryos. However, the mechanistic quantitation of the epigenetic interactions between sperms and oocytes and the related impact on embryo development are still not clear [6,7]. In this study, Wang et al., [8] develop a modeling framework that addresses this question by integrating game theory and the latest discoveries of the epigenetic control of embryo development. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

    Science.gov (United States)

    Zhang, Y. P.; Liu, Yi; Luo, X. B.; Isobe, M.; Yuan, G. L.; Liu, Y. Q.; Hua, Y.; Song, X. Y.; Yang, J. W.; Li, X.; Chen, W.; Li, Y.; Yan, L. W.; Song, X. M.; Yang, Q. W.; Duan, X. R.

    2014-05-01

    A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y. Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team, Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported.

  15. Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Y. P., E-mail: zhangyp@swip.ac.cn; Liu, Yi; Yuan, G. L.; Song, X. Y.; Yang, J. W.; Li, X.; Chen, W.; Li, Y.; Yan, L. W.; Song, X. M.; Yang, Q. W.; Duan, X. R. [Southwestern Institute of Physics, P.O. Box 432, Chengdu 610041 (China); Luo, X. B.; Liu, Y. Q.; Hua, Y. [Institute of Nuclear Science and Technology, Sichuan University, Chengdu 610041 (China); Isobe, M. [National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5259 (Japan)

    2014-05-15

    A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y. Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team , Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported.

  16. Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

    International Nuclear Information System (INIS)

    Zhang, Y. P.; Liu, Yi; Yuan, G. L.; Song, X. Y.; Yang, J. W.; Li, X.; Chen, W.; Li, Y.; Yan, L. W.; Song, X. M.; Yang, Q. W.; Duan, X. R.; Luo, X. B.; Liu, Y. Q.; Hua, Y.; Isobe, M.

    2014-01-01

    A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y. Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team , Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported

  17. Process optimization and evaluation of novel baicalin solid nanocrystals

    Directory of Open Access Journals (Sweden)

    Yue PF

    2013-08-01

    Full Text Available Peng-Fei Yue,1,2 Yu Li,1 Jing Wan,1 Yong Wang,1 Ming Yang,1 Wei-Feng Zhu,1 Chang-Hong Wang,2 Hai-Long Yuan31Key Lab of Modern Preparation of TCM, Jiangxi University of Traditional Chinese Medicine, Nanchang, 2Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 3302 Hospital of PLA Institute of Chinese Materia Medica, Beijing, People's Republic of ChinaAbstract: The objective of this study was to prepare baicalin solid nanocrystals (BCN-SNS to enhance oral bioavailability of baicalin. A Box–Behnken design approach was used for process optimization. The physicochemical properties and pharmacokinetics of the optimal BCN-SNS were investigated. Multiple linear regression analysis for process optimization revealed that the fine BCN-SNS was obtained wherein the optimal values of homogenization pressure (bar, homogenization cycles (cycles, amount of TPGS to drug (w/w, and amount of MCCS to drug (w/w were 850 bar, 25 cycles, 10%, and 10%, respectively. Transmission electron microscopy and scanning electron microscopy results indicated that no significant aggregation or crystal growth could be observed in the redispersed freeze-dried BCN-SNS. Differential scanning calorimetry and X-ray diffraction results showed that BCN remained in a crystalline state. Dissolution velocity of the freeze-dried BCN-SNS powder was distinctly superior compared to those of the crude powder and physical mixture. The bioavailability of BCN in rats was increased remarkably after oral administration of BCN-SNS (P < 0.05, compared with those of BCN or the physical mixture. The SNS might be a good choice for oral administration of poorly soluble BCN, due to an improvement of the bioavailability and dissolution velocity of BCN-SNS.Keywords: baicalin, solid nanocrystals, optimization, in vivo/vitro evaluation

  18. Yi Qi Qing Re Gao-containing serum inhibits lipopolysaccharide-induced rat mesangial cell proliferation by suppressing the Wnt pathway and TGF-β1 expression.

    Science.gov (United States)

    Yang, Liping; Sun, Xueyan; Zhan, Yongli; Liu, Huijie; Wen, Yumin; Mao, Huimin; Dong, X I; Li, Ping

    2016-04-01

    The aim of the present study was to investigate the effect of Yi Qi Qing Re Gao-containing serum (YQ-S) on rat mesangial cell (MC) proliferation and to investigate the underlying mechanism. MCs were divided into the control, lipopolysaccharide (LPS)-stimulated, YQ-S and fosinopril-containing serum (For-S) groups, and cultured for 48 h. An MTT assay was used to evaluate the proliferation of MCs. In addition, reverse transcription-quantitative polymerase chain reaction and western blot analysis were conducted to detect the expression levels of Wnt4, β-catenin and transforming growth factor (TGF)-β1 in MCs. The results indicated that YQ-S inhibited LPS-induced MC proliferation. The Wnt4 and TGF-β1 mRNA expression levels were reduced in the YQ-S group (P<0.01 or P<0.05). Furthermore, the Wnt4, β-catenin and TGF-β1 protein expression levels were suppressed in the YQ-S group (P<0.01 or P<0.05). Therefore, YQ-S appears to inhibit MC proliferation, and its mechanism may involve the inhibition of the Wnt signaling pathway and downregulation of TGF-β1 expression.

  19. Local sustained delivery of acetylsalicylic acid via hybrid stent with biodegradable nanofibers reduces adhesion of blood cells and promotes reendothelialization of the denuded artery

    Directory of Open Access Journals (Sweden)

    Lee CH

    2014-01-01

    Full Text Available Cheng-Hung Lee,1,2 Yu-Huang Lin,3 Shang-Hung Chang,1 Chun-Der Tai,3 Shih-Jung Liu,2 Yen Chu,4 Chao-Jan Wang,5 Ming-Yi Hsu,5 Hung Chang,6 Gwo-Jyh Chang,7 Kuo-Chun Hung,1 Ming-Jer Hsieh,1 Fen-Chiung Lin,1 I-Chang Hsieh,1 Ming-Shien Wen,1 Yenlin Huang81Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Linkou, 2Department of Mechanical Engineering, 3Graduate Institute of Medical Mechatronics, Chang Gung University, 4Laboratory of Cardiovascular Physiology, Division of Thoracic and Cardiovascular Surgery, 5Department of Medical Imaging and Intervention, 6Hematology-Oncology Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, 7Graduate Institute of Clinical Medicinal Sciences, Chang Gung University College of Medicine, Linkou, 8Department of Anatomical Pathology, Chang Gung Memorial Hospital, Linkou, Tao-Yuan, TaiwanAbstract: Incomplete endothelialization, blood cell adhesion to vascular stents, and inflammation of arteries can result in acute stent thromboses. The systemic administration of acetylsalicylic acid decreases endothelial dysfunction, potentially reducing thrombus, enhancing vasodilatation, and inhibiting the progression of atherosclerosis; but, this is weakened by upper gastrointestinal bleeding. This study proposes a hybrid stent with biodegradable nanofibers, for the local, sustained delivery of acetylsalicylic acid to injured artery walls. Biodegradable nanofibers are prepared by first dissolving poly(D,L-lactide-co-glycolide and acetylsalicylic acid in 1,1,1,3,3,3-hexafluoro-2-propanol. The solution is then electrospun into nanofibrous tubes, which are then mounted onto commercially available bare-metal stents. In vitro release rates of pharmaceuticals from nanofibers are characterized using an elution method, and a high-performance liquid chromatography assay. The experimental results suggest that biodegradable nanofibers

  20. A 10-year retrospective study of alterative aeroallergens sensitization spectrum in urban children with allergic rhinitis

    Directory of Open Access Journals (Sweden)

    Yang LF

    2018-02-01

    Full Text Available Li-Fen Yang,1,* Liang-Ming Cai,1,* Ming Li,2,* Jin-Tao Liu,3 Zhao-Ni Wang,1 Wei-Hao Wang,4 Qin-tai Yang,4 Zhuang-Gui Chen1,5 1Department of Pediatrics Intensive Care Unit and Respiratory Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Department of Pulmonary Diseases, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China; 3Department of Population and Quantitative Health Science, Case Western Reserve University, Cleveland, OH, USA; 4Department of Otorhinolaryngology-Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People’s Republic of China; 5Institution of Respiratory Diseases of Sun Yat-sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Objective: To investigate the alterative spectrum and trends of aeroallergens sensitization in children with allergic rhinitis (AR in Guangzhou, China in the past 10 years.Participants and methods: In this retrospective study, 4,111 children with complaints of nasal hyper-reactivity who visited the Pediatric Department and/or Otolaryngology Department from January 2007 to November 2016 were enrolled. Serum specific immunoglobulin E was measured and positive detection was made in 3,328 patients, who were, therefore, diagnosed with AR. Positive rates and trends of different aeroallergens sensitization were assessed. The tendency of positive rates changing over the years, and the difference and trends in positive rate of aeroallergen sensitization that occurred in subgroups of gender, age, and season were determined and analyzed with logistic regression.Results: The percentage of detected common aeroallergens in AR children was (from high to low 81.07%, 34.44%, 14.72%, 11.81%, 6.04%, and 3.70% for house dust mites (HDMs, cat–dog dander, cockroach, mold mixture, tree pollen mixture, and herb pollen mixture

  1. Patterns of HIV prevalence among injecting drug users in the cross-border area of Lang Son Province, Vietnam, and Ning Ming County, Guangxi Province, China

    Directory of Open Access Journals (Sweden)

    Hoang Tran V

    2005-08-01

    Full Text Available Abstract Background To assess patterns of injecting drug use and HIV prevalence among injecting drug users (IDUs in an international border area along a major heroin trans-shipment route. Methods Cross-sectional surveys of IDUs in 5 sites in Lang Son Province, Vietnam (n = 348 and 3 sites in Ning Ming County, Guangxi Province, China (n = 308. Respondents were recruited through peer referral ("snowball" methods in both countries, and also from officially recorded lists of IDUs in Vietnam. A risk behavior questionnaire was administered and HIV counseling and testing conducted. Results Participants in both countries were largely male, in their 20s, and unmarried. A majority of subjects in both countries were members of ethnic minority groups. There were strong geographic gradients for length of drug injecting and for HIV seroprevalence. Both mean years injecting and HIV seroprevalence declined from the Vietnamese site farthest from the border to the Chinese site farthest from the border. 10.6% of participants in China and 24.5% of participants in Vietnam reported crossing the international border in the 6 months prior to interview. Crossing the border by IDUs was associated with (1 distance from the border, (2 being a member of an ethnic minority group, and (3 being HIV seropositive among Chinese participants. Conclusion Reducing the international spread of HIV among IDUs will require programs at the global, regional, national, and "local cross border" levels. At the local cross border level, the programs should be coordinated on both sides of the border and on a sufficient scale that IDUs will be able to readily obtain clean injection equipment on the other side of the border as well as in their country of residence.

  2. Targeting cancer stem cells: emerging role of Nanog transcription factor

    Directory of Open Access Journals (Sweden)

    Wang ML

    2013-09-01

    Full Text Available Mong-Lien Wang,1 Shih-Hwa Chiou,2,3 Cheng-Wen Wu1,4–61Institute of Biochemistry and Molecular Biology, 2Institute of Pharmacology, National Yang Ming University, Taipei, Taiwan; 3Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan; 4Institute of Microbiology and Immunology, 5Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan; 6Institute of Biomedical Science, Academia Sinica, Taipei, TaiwanAbstract: The involvement of stemness factors in cancer initiation and progression has drawn much attention recently, especially after the finding that introducing four stemness factors in somatic cells is able to reprogram the cells back to an embryonic stem cell-like state. Following accumulating data revealing abnormal elevated expression levels of key stemness factors, like Nanog, Oct4, and Sox2, in several types of cancer stem cells; the importance and therapeutic potential of targeting these stemness regulators in cancers has turned to research focus. Nanog determines cell fate in both embryonic and cancer stem cells; activating Nanog at an inappropriate time would result in cancer stem cells rather than normal pluripotent stem cells or differentiated somatic cells. Upregulated Nanog is correlated with poor survival outcome of patients with various types of cancer. The discoveries of downstream regulatory pathways directly or indirectly mediated by Nanog indicate that Nanog regulates several aspects of cancer development such as tumor cell proliferation, self-renewal, motility, epithelial-mesenchymal transition, immune evasion, and drug-resistance, which are all defined features for cancer stem cells. The current review paper illustrates the central role of Nanog in the regulatory networks of cancer malignant development and stemness acquirement, as well as in the communication between cancer cells and the surrounding stroma. Though a more defined model is needed to test the

  3. ‘Quadrilateral’ in Philosophy and Bie-modernism (Comments on Aleš Erjavec’s “Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang's Article ‘The Bustle and the Absence of Zhuyi’”

    Directory of Open Access Journals (Sweden)

    Wang Jianjiang

    2017-09-01

    Full Text Available Aleš Erjavec proposed the global philosophical quadrilateral, giving Chinese philosophy, aesthetics, and humanities an expectation. However, the realization of this expectation hinges on the question whether Chinese philosophy as well as aesthetics and the humanities can rid themselves of the staggering level of ‘voice’ and develop their ‘speech’. To make ‘speech’, any nation should have its own idea, theory and Zhuyi. How to overcome the embarrassment that ‘quadrilateral’ expectation implies? Time spatialization and four-phase development theories of the Bie-modern, and great leap forward pause theory have provided an answer. The quadrilateral expectation as shown by Aleš Erjavec, is encountering the antagonism between ‘cosmopolitanism’ and ‘nationalism’. The key to resolving this antagonism is ‘my’ original achievement consisting of ‘Chinese traditional philosophy, Western philosophy, Marxism and I (myself’. Bie-modernism is a Zhuyi of self-regulation, self-renewal and self-transcendence and of their practical implementation.   Article received: May 21, 2017; Article accepted: May 24, 2017; Original scholarly paper How to cite this article: Jianjiang, Wang. "‘Quadrilateral’ in Philosophy and Bie-modernism (Comments on Aleš Erjavec’s “Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang's Article ‘The Bustle and the Absence of Zhuyi’”." AM Journal of Art and Media Studies 13 (2017: 123-142. doi: 10.25038/am.v0i13.190

  4. 从“辽燕旧界”到“华夷大界”——朝鲜人笔下的山海关意象%From "the Boundary Beween Liao and Yan" to "the Boundary Beween Hua and Yi" : Shanhaiguan as Described by Koreans in the Ming and Qing Dynasties

    Institute of Scientific and Technical Information of China (English)

    黄普基

    2012-01-01

    明朝时期,朝鲜人并无以山海关为界、关内外华夷不同的“分界”概念。但明清易代,政治局面的巨变促使朝鲜人大大地强化了华夷分界的意识,以致最终认定山海关为明晰的“界线”。具体而言,清时期朝鲜人对关内的种种自然、人文景观往往表现出令人惊叹的宽容和肯定;相反,对关外却持着过于苛刻的否定态度。然而,有趣的是,清时期朝鲜人对关内外分界意识逐渐强化之时,两地的文化差距实际上却在日益缩小。而且,关内永平府与关外辽西之间,其相似性甚至大于差异性。%The concept that Shanhaiguan was the boundary between Chinese and foreigners did not exist at all among Koreans in the Ming Dynasty, but the concept was greatly strengthened but great political changes during the Ming-Qing transition. Koreans was surprisingly tolerant and positive towards the natural and humane landscape inside the Pass, but was overly severe and negative towards the landscape outside the Pass in the Qing Dynasty. Interestingly, the cultural distinction between inside the Pass and outside the Pass was reduced day by day while the boundary conception was gradually being strengthened in the Qing Dynasty, even though the resemblance was more than the distinction between inside the Pass and outside the Pass.

  5. Mortal Ancestors, Immortal Images: Zhang Dai’s Biographical Portraits

    OpenAIRE

    Duncan M. Campbell

    2012-01-01

    Towards the end of his long life, the prolific late-Ming historian and essayist Zhang Dai 張岱 (1597-?1684) completed a book that he had been working on for many years. Entitled Portraits of the Eminent and Worthy Immortals of Zhejiang During the Ming Dynasty (You Ming yuyue san bu xiu tuzan 有明於越三不朽名賢圖贊) the book included the short biographies (with poetic panegyrics) and portraits of 109 men and women of Zhang Dai’s hometown of Shaoxing, one of the epicentres of China’s élite cultural life. Th...

  6. Retracted: Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation, by L Wang, SG Zellmer, DM Printzenhoff and NA Castle. British Journal of Pharmacology, volume 172(20): 4905-4918, published in October 2015; DOI 10.1111/bph.13259.

    Science.gov (United States)

    2018-07-01

    The above article, published by the British Journal of Pharmacology in October 2015 (https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13259), has been retracted by agreement between the authors, the journal Editor in Chief and John Wiley & Sons Limited. The retraction has been agreed owing to the discovery of errors in the chemical structure of the synthetic compounds generated. The corrected structure is now available in the article PF-06526290 can both enhance and inhibit conduction through voltage gated sodium channels by L Wang, SG Zellmer, DM Printzenhoff and NA Castle, 2018, https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14338. Reference Wang L, Zellmer SG, Printzenhoff DM, Castle NA (2015). Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation. Br J Pharmacol 172: 4905-4918. https://doi.org/10.1111/bph.13259. © 2018 The British Pharmacological Society.

  7. 古今文献中与“尪痹”相关的病证名研究%A Study on the Disorders Relevant with“ Wang Bi”in the Ancient and Modern Literatures

    Institute of Scientific and Technical Information of China (English)

    孟小燕; 王育林

    2016-01-01

    Differentiation of disease and differentiation of syndrome are equally important in the di-agnosis and treatment of TCM. Disease is the entire process of some abnormal life state and syndrome is a cer-tain stage in the abnormal process in the life. The terms of disease and syndrome are related with each other. In the study of the ancient and modern literatures on the term Wang Bi(尪痹),it was found that the term for syndrome was also involved. Wang Bi(尪痹)is the new term of a disease proposed by TCM master,Jiao Shude. By investigating the name and origin of the disease,Wan Bi was identified as the term of syndrome. The connection of Wang Bi(尪痹)and Wan Bi was attempted to build so as to contribute to the correct un-derstanding of the disease and construction of medical history in TCM.%中医诊治强调辨病与辨证并重,中医学探讨某病时兼及“病”“证”。疾病指人体某种异常生命状态的全过程,而证候是这个全部生命异常过程中的某个阶段。病证名即与病、证发生发展相关的称谓。在考察古今文献中与“尪痹”相关称谓时,发现还有证名的存在,因此为客观全面,该文使用了“病证名”而非“病名”的概念。“尪痹”是已故中医学家焦树德提出的新病名,考察古今文献中与“尪痹”相关的称谓,可以发现还有证名的存在。对这些病证的名实与源流进行考察,考证“尪痹”之源,辨析病证名“顽痹”。力图呈现与“尪痹”相关病证名的大致面貌,以利于准确把握这一疾病,俾于中医疾病史的建构。

  8. DOD Civilian and Contractor Workforces: Additional Cost Savings Data and Efficiencies Plan are Needed

    Science.gov (United States)

    2016-10-01

    Enterprise-wide Contractor Manpower Reporting Application (ECMRA) across all its components, and which will continue to improve reporting of...costs: Not applicable yes (estimated) no (estimated) Source: GAO analysis of DOD’s February 2016 status report | GAO-17-128 aNumber of...and interviewed DOD officials. What GAO Recommends GAO previously recommended that DOD fully address ongoing section 955 requirements, such as

  9. 通过韩半岛铁搭看明清时代江南的水田农业%Paddy Field Farming of the Jiangnan Region in the Ming and Qing Dynasties Seen from the Pitchfork from Korean Penninsula

    Institute of Scientific and Technical Information of China (English)

    崔德卿

    2012-01-01

    Pitchfork, firstly appeari ng in Wangzhen Agriculture Books, was distributed around the southern region of the Korean peninsula since the 2nd century BC and from there went over to China before the Tang dynasty. This is far different in production technique from the pitchfork of China after the Yuan dynasty, and the production technique and the shape of the pitchfork of the Korean peninsula in those days are still continuing up to this time. There are multiple factors in the widespread distribution of pitchfork in Jiangnan re- gion. Before anything else, the change in social circumstances of the Ming and Qing dynasties decreased the household landholding area and increased the production of commercial crops and the chances for employed labor. It therefore provided for the conditions to supplement the loss from the failure to use cattle ploughing and to compensate the labor productivity of hoes with the mutually-aided farming. The paddy fields' strong clay soil also made it unsuitable to introduce the ploughs from Jiangdong. In the farming in Jiangnan of the Ming and Qing dynasties, as a result, the pitchfork came to establish itself as a main farming tool for the deep ploughing and heavy fertilizer.%铁搭是具有2—4个铁齿的耕地专用农具,是一种为江南水田的深耕起到决定性作用的代耕用具。本文论证铁搭在唐朝时期由韩半岛的济州岛传播到中国的过程。明清时代的铁搭可与江东犁媲美,它时于引领江南农业经济发展所起的实质性作用是功不可没的。而韩半岛南部则早在一世纪起就已出现铁搭,因为和汉魏王朝的交易活跃的原因,铁搭虽然有很早传来的可能性,但根据在北宋时期扬州的铁搭形态上猜测,比起三韩时代,三国时代(韩)即中国唐代之前传来的可能性更高。

  10. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. MING-HSIANG SHIH. Articles written in Sadhana. Volume 33 Issue 6 December 2008 pp 767-779. Development of digital image correlation method to analyse crack variations of masonry wall · Shih-Heng Tung Ming-Hsiang Shih Wen-Pei Sung · More Details Abstract Fulltext PDF. The detection ...

  11. The Reality Of The Homeland Security Enterprise Information Sharing Environment

    Science.gov (United States)

    2017-12-01

    Related Information to Protect the Homeland (GAO 15- 290) (Washington, DC: U.S. Government Accountability Office, 2015), http://www.gao.gov/ assets...Government Accountability Office [GAO], Information Sharing Environment Better Road Map Needed to Guide Implementation and Investments (GAO-11-455...and its ISE PM would have clearer accountability for information sharing lapses and a faster ability to reform or develop domestic information -sharing

  12. Image Mosaicking Approach for a Double-Camera System in the GaoFen2 Optical Remote Sensing Satellite Based on the Big Virtual Camera.

    Science.gov (United States)

    Cheng, Yufeng; Jin, Shuying; Wang, Mi; Zhu, Ying; Dong, Zhipeng

    2017-06-20

    The linear array push broom imaging mode is widely used for high resolution optical satellites (HROS). Using double-cameras attached by a high-rigidity support along with push broom imaging is one method to enlarge the field of view while ensuring high resolution. High accuracy image mosaicking is the key factor of the geometrical quality of complete stitched satellite imagery. This paper proposes a high accuracy image mosaicking approach based on the big virtual camera (BVC) in the double-camera system on the GaoFen2 optical remote sensing satellite (GF2). A big virtual camera can be built according to the rigorous imaging model of a single camera; then, each single image strip obtained by each TDI-CCD detector can be re-projected to the virtual detector of the big virtual camera coordinate system using forward-projection and backward-projection to obtain the corresponding single virtual image. After an on-orbit calibration and relative orientation, the complete final virtual image can be obtained by stitching the single virtual images together based on their coordinate information on the big virtual detector image plane. The paper subtly uses the concept of the big virtual camera to obtain a stitched image and the corresponding high accuracy rational function model (RFM) for concurrent post processing. Experiments verified that the proposed method can achieve seamless mosaicking while maintaining the geometric accuracy.

  13. Scaling behavior can be tricky: Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

    Science.gov (United States)

    Hui, Pak Ming; Xu, Chen

    2015-09-01

    Evolutionary game theory is a powerful tool for studying the emergence of cooperation among competing individuals [1]. Popularly studied games include the prisoner's dilemma [2], snowdrift game [3] and stag hunt game [4]. They have been extensively studied for the extent of cooperative behavior under different dilemma strengths. Generally, the games can be defined by a 2 × 2 matrix and thus four payoff elements, T, R, P, and S, for the possible payoffs to players when they use pure strategies against each other. Detailed definitions of the four payoffs are given in the review by Wang et al. [5]. For simplicity, it is often the case that fewer parameters are invoked, e.g. a single parameter [3] and more generally two parameters [6]. Generally speaking, reducing the number of parameters has the effect of restricting the system to a certain subspace of the unreduced case. In addition, the spatial structures, such as a well-mixed population or a population forming a complex network, that govern the competing relationship and environment of the agents, and the evolutionary rules, that govern how agents update their strategies, are vital in determining how cooperation evolves, as well documented in the references of [5].

  14. PREFACE: MRS International Materials Research Conference (IMRC-2008)

    Science.gov (United States)

    Wang, Zhanguo; Qiu, Yong; Li, Yongxiang

    2009-03-01

    This volume contains selected papers presented at the MRS International Materials Research Conference (IMRC-2008) held in Chongqing, China, 9-12 June 2008. IMRC-2008 included 9 symposia of A. Eco/Environmental Materials, B. Sustainable Energy Materials, C. Electronic Packaging Materials, D. Electronic Materials, E. Materials and Processes for Flat-panel Displays, F. Functional Ceramics, G. Transportation Materials, H. Magnesium and I. Biomaterials for Medical Applications. Nearly 1200 participants from 33 countries attended the conference, and the conference organizers received more than 700 papers. After the peer review processes, 555 papers were selected to be published in 9 Journals or proceedings, including J. of Materials Research (JMR), Rare Metal Materials and Engineering, J. of Univ. Science and Technology Beijing, Biomedical Materials: Materials for Tissue Engineering and Regenerative Medicine, Chinese Journal of Aeronautics, Materials Science Forum, and Journal of Physics: Conference Series. Among the 555 selected papers, 91 papers are published in this volume, and the topics mainly cover electronic matrials, processes for flat-panel displays and functional ceramics. The editors would like to give special thanks to the graduate students Liwu Jiang, Ming Li and Di He from Beihang University for their hard work compiling and typesetting each paper in this volume. Zhanguo Wang, Yong Qiu and Yongxiang Li Editors

  15. Current applications and future prospects of nanomaterials in tumor therapy

    Directory of Open Access Journals (Sweden)

    Huang Y

    2017-03-01

    Full Text Available Yu Huang,1 Chao-Qiang Fan,1 Hui Dong,1 Su-Min Wang,1 Xiao-Chao Yang,2 Shi-Ming Yang1 1Department of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, People’s Republic of China; 2Department of Biomedical Materials Science, School of Biomedical Engineering, Third Military Medical University, Chongqing, People’s Republic of China Abstract: Tumors are one of the most serious human diseases and cause numerous global deaths per year. In spite of many strategies applied in tumor therapy, such as radiation therapy, chemotherapy, surgery, and a combination of these treatments, tumors are still the foremost killer worldwide among human diseases, due to their specific limitations, such as multidrug resistance and side effects. Therefore, it is urgent and necessary to develop new strategies for tumor therapy. Recently, the fast development of nanoscience has paved the way for designing new strategies to treat tumors. Nanomaterials have shown great potential in tumor therapy, due to their unique properties, including passive targeting, hyperthermia effects, and tumor-specific inhibition. This review summarizes the recent progress using the innate antitumor properties of metallic and nonmetallic nanomaterials to treat tumors, and related challenges and prospects are discussed. Keywords: tumor, nanomaterials, nanoparticles, nanotechnology

  16. Global Production: The Case of Offshore Programming

    DEFF Research Database (Denmark)

    Nørbjerg, Jacob; Havn, Erling; Bansler, Jørgen P.

    1997-01-01

    of software is no exception.In this paper, we present a newly started research project on offshore program-ming, that is the practice of sending software development “offshore,” to India or other low wage areas. The project focuses on the organisation of offshore program-ming and, particularly, on the role...

  17. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Ming-Hsiang Shih. Articles written in Sadhana. Volume 33 Issue 6 December 2008 pp 767-779. Development of digital image correlation method to analyse crack variations of masonry wall · Shih-Heng Tung Ming-Hsiang Shih Wen-Pei Sung · More Details Abstract Fulltext PDF. The detection of ...

  18. The Education and Lifestyle of the Chinese Literati. Lesson Plan.

    Science.gov (United States)

    Smithsonian Institution, Washington, DC. Arthur M. Sackler Gallery.

    This teaching package describes the education and lifestyle of the Chinese literati, popular from the Ming to the Qing dynasties (1368-1911). It consists of four lesson plans and a teacher's guide to a slide set. The latter illustrates painting formats popular during the late Ming period (1573-1644), hanging scrolls, handscrolls, the album leaf,…

  19. Biochemical Conservation and Evolution of Germacrene A Oxidase in Asteraceae*

    Science.gov (United States)

    Nguyen, Don Trinh; Göpfert, Jens Christian; Ikezawa, Nobuhiro; MacNevin, Gillian; Kathiresan, Meena; Conrad, Jürgen; Spring, Otmar; Ro, Dae-Kyun

    2010-01-01

    Sesquiterpene lactones are characteristic natural products in Asteraceae, which constitutes ∼8% of all plant species. Despite their physiological and pharmaceutical importance, the biochemistry and evolution of sesquiterpene lactones remain unexplored. Here we show that germacrene A oxidase (GAO), evolutionarily conserved in all major subfamilies of Asteraceae, catalyzes three consecutive oxidations of germacrene A to yield germacrene A acid. Furthermore, it is also capable of oxidizing non-natural substrate amorphadiene. Co-expression of lettuce GAO with germacrene synthase in engineered yeast synthesized aberrant products, costic acids and ilicic acid, in an acidic condition. However, cultivation in a neutral condition allowed the de novo synthesis of a single novel compound that was identified as germacrene A acid by gas and liquid chromatography and NMR analyses. To trace the evolutionary lineage of GAO in Asteraceae, homologous genes were further isolated from the representative species of three major subfamilies of Asteraceae (sunflower, chicory, and costus from Asteroideae, Cichorioideae, and Carduoideae, respectively) and also from the phylogenetically basal species, Barnadesia spinosa, from Barnadesioideae. The recombinant GAOs from these genes clearly showed germacrene A oxidase activities, suggesting that GAO activity is widely conserved in Asteraceae including the basal lineage. All GAOs could catalyze the three-step oxidation of non-natural substrate amorphadiene to artemisinic acid, whereas amorphadiene oxidase diverged from GAO displayed negligible activity for germacrene A oxidation. The observed amorphadiene oxidase activity in GAOs suggests that the catalytic plasticity is embedded in ancestral GAO enzymes that may contribute to the chemical and catalytic diversity in nature. PMID:20351109

  20. Student Loans: Oversight of Servicemembers Interest Rate Cap Could Be Strengthened

    Science.gov (United States)

    2016-11-01

    McDonald (Analyst-in-Charge), Jeffrey G. Miller, and Jill Yost. Additional assistance was provided by Susan Aschoff, James Bennett, Mark Bird...correspondence. To have GAO e-mail you a list of newly posted products, go to http://www.gao.gov and select “E-mail Updates.” The price of each GAO publication...printed in color or black and white. Pricing and ordering information is posted on GAO’s website, http://www.gao.gov/ordering.htm. Place orders by

  1. Nuclear Weapons: DOD Assessed the Need for Each Leg of the Strategic Triad and Considered Other Reductions to Nuclear Forces

    Science.gov (United States)

    2016-09-01

    check, or money order. Call for additional information. Connect with GAO on Facebook , Flickr, Twitter, and YouTube. Subscribe to our RSS Feeds or E...GAO Reports and Testimony Order by Phone Connect with GAO To Report Fraud , Waste, and Abuse in Federal Programs Congressional Relations Public

  2. The identification of Chenghua white and blue porcelain by using PIXE and multivariate statistical analysis

    International Nuclear Information System (INIS)

    Cheng Huansheng; Zhang Zhengquan; Yao Hua

    2001-01-01

    The major and minor chemical compositions of ancient white and blue porcelain made in Chenghua empire, Ming Dynasty and in Kangxi empire, Qing Dynasty have been determined by PIXE. Experimental results show that a real precious Chenghua white and blue porcelain made in Ming Dynasty at Kuan Kiln can be distinguished from the fakes made in Kangxi empire, Qing Dynasty

  3. Index of Reports and Testimony: Fiscal Year 1991.

    Science.gov (United States)

    1991-12-01

    74FS, Apr. 24 U.S.-Mexico Trade: Some U.S. Wood Furniture Firms Relocated From Los Angeles Area to Mexico GAO NSIAD-91-191 Apr. 24 El Comercio Entre U.S...Testimony: Fiscal Year 1991 El Comercio Entry Los EE. UU. y Mexico: Informacion acerca de la reglamentacion ambiental y su cumplimiento GAO NSIAi)-91-227SV...Considerations GAO/RCED-91-240 Sept. 17 Air Traffic Control: FAA’s Transition of Communications System to Digital Technology GAO/IMTEC-91-77FS Sept. 26

  4. Design Genetic Algorithm Optimization Education Software Based Fuzzy Controller for a Tricopter Fly Path Planning

    Science.gov (United States)

    Tran, Huu-Khoa; Chiou, Juing -Shian; Peng, Shou-Tao

    2016-01-01

    In this paper, the feasibility of a Genetic Algorithm Optimization (GAO) education software based Fuzzy Logic Controller (GAO-FLC) for simulating the flight motion control of Unmanned Aerial Vehicles (UAVs) is designed. The generated flight trajectories integrate the optimized Scaling Factors (SF) fuzzy controller gains by using GAO algorithm. The…

  5. Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells

    Directory of Open Access Journals (Sweden)

    Tang XJ

    2016-10-01

    Full Text Available Xiang-Jun Tang,1,* Kuan-Ming Huang,1,* Hui Gui,1,* Jun-Jie Wang,2 Jun-Ti Lu,1 Long-Jun Dai,1,3 Li Zhang,1 Gang Wang2 1Department of Neurosurgery, TaiHe Hospital, Hubei University of Medicine, Shiyan, 2Department of Pharmaceutics, Shanghai Eighth People’s Hospital, Jiangsu University, Shanghai, People’s Republic of China; 3Department of Surgery, University of British Columbia, Vancouver, BC, Canada *These authors contributed equally to this work Abstract: As one of the natural herbal flavonoids, myricetin has attracted much research interest, mainly owing to its remarkable anticancer properties and negligible side effects. It holds great potential to be developed as an ideal anticancer drug through improving its bioavailability. This study was performed to investigate the effects of Pluronic-based micelle encapsulation on myricetin-induced cytotoxicity and the mechanisms underlying its anticancer properties in human glioblastoma cells. Cell viability was assessed using a methylthiazol tetrazolium assay and a real-time cell analyzer. Immunoblotting and quantitative reverse transcriptase polymerase chain reaction techniques were used for determining the expression levels of related molecules in protein and mRNA. The results indicated that myricetin-induced cytotoxicity was highly potentiated by the encapsulation of myricetin. Mitochondrial apoptotic pathway was demonstrated to be involved in myricetin-induced glioblastoma cell death. The epidermal growth factor receptor (EGFR/PI3K/Akt pathway located in the plasma membrane and cytosol and the RAS-ERK pathway located in mitochondria served as upstream and downstream targets, respectively, in myricetin-induced apoptosis. MiR-21 inhibitors interrupted the expression of EGFR, p-Akt, and K-Ras in the same fashion as myricetin-loaded mixed micelles (MYR-MCs and miR-21 expression were dose-dependently inhibited by MYR-MCs, indicating the interaction of miR-21 with MYR-MCs. This study provided evidence

  6. Low acetate concentrations favor polyphosphate-accumulating organisms over glycogen-accumulating organisms in enhanced biological phosphorus removal from wastewater.

    Science.gov (United States)

    Tu, Yunjie; Schuler, Andrew J

    2013-04-16

    Glycogen-accumulating organisms (GAOs) are thought to compete with polyphosphate-accumulating organisms (PAOs) in enhanced biological phosphorus removal (EBPR) wastewater treatment systems. A laboratory sequencing batch reactor (SBR) was operated for one year to test the hypothesis that PAOs have a competitive advantage at low acetate concentrations, with a focus on low pH conditions previously shown to favor GAOs. PAOs dominated the system under conventional SBR operation with rapid acetate addition (producing high in-reactor concentrations) and pH values of 7.4-8.4. GAOs dominated when the pH was decreased (6.4-7.0). Decreasing the acetate addition rate led to very low reactor acetate concentrations, and PAOs recovered, supporting the study hypothesis. When the acetate feed rate was increased, EBPR failed again. Dominant PAOs and GAOs were Candidatus Accumulibacter phosphatis and Defluviicoccus Cluster 2, respectively, according to fluorescent in situ hybridization and 454 pyrosequencing. Surprisingly, GAOs were not the immediate causes of PAO failures, based on functional and population measurements. Pyrosequencing results suggested Dechloromonas and Tetrasphaera spp. may have also been PAOs, and additional potential GAOs were also identified. Full-scale systems typically have lower in-reactor acetate concentrations than laboratory SBRs, and so, previous laboratory studies may have overestimated the practical importance of GAOs as causes of EBPR failure.

  7. Elections: DOD Needs More Comprehensive Planning to Address Military and Overseas Absentee Voting Challenges

    Science.gov (United States)

    2016-04-01

    Acknowledgments Contact Acknowledgments Related GAO Products Page 75 GAO-16-378 DOD Overseas Absentee Voting U.S. Postal Service: Actions... Products Page 76 GAO-16-378 DOD Overseas Absentee Voting Election Reform: Nine States’ Experiences Implementing Federal Requirements for...ELECTIONS DOD Needs More Comprehensive Planning to Address Military and Overseas Absentee Voting Challenges

  8. Game theory in epigenetic reprogramming. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Hsu, Fei-Man; Chen, Pao-Yang

    2017-03-01

    Von Neumann and Morgenstern published the Theory of Games and Economic Behavior in 1944, describing game theory as a model in which intelligent rational decision-makers manage to find their best strategies in conflict, cooperative or other mutualistic relationships to acquire the greatest benefit [1]. This model was subsequently incorporated in ecology to simulate the ;fitness; of a species during natural selection, designated evolutionary game theory (EGT) [2]. Wang et al. proposed ;epiGame;, taking paternal and maternal genomes as ;intelligent; players that compete, cooperate or both during embryogenesis to maximize the fitness of the embryo [3]. They further extended game theory to an individual or single cell environment. During early zygote development, DNA methylation is reprogrammed such that the paternal genome is demethylated before the maternal genome. After the reset, the blastocyst is re-methylated during embryogenesis. At that time, the paternal and maternal genomes have a conflict of interest related to the expression of their own genes. The proposed epiGame models such interactive regulation between the parental genomes to reach a balance for embryo development (equation (2)).

  9. oreans’ Perception of the Liaodong Region During the Chosŏn Dynasty

    Directory of Open Access Journals (Sweden)

    Jungshin Lee

    2016-02-01

    Full Text Available Liaodong refers to the southeastern part of Liaoning Province today. During the Three Kingdoms Era, this area was part of Koguryŏ territory, and after the collapse of Koguryŏ, it belonged to Parhae. However, when Parhae fell at the hands of the Jurchens, the Koryŏ dynasty was unable to secure Liaodong. Afterwards, with the rise of the Chinese Yuan dynasty, King Ch’ungsŏn of Koryŏ was appointed by the Yuan emperor as the King of Shenyang, and the movement to reclaim Liaodong began to gain momentum in Korea. Succeeding Koryŏ, the Chosŏn dynasty claimed to support Ming China under the principle of sadae, but this did not mean that relations between Chosŏn and Ming were stabilized. As a result, Chosŏn could not but worry about the fact that if the Ming were to suppress the Jurchens, Chosŏn would be Ming’s next target. To prevent a Ming invasion of Korea, Chosŏn had to make an ally of the Jurchens and launch a preemptive attack to annex Liaodong. With this in mind, Chŏng Tojŏn joined hands with T’aejo Yi Sŏnggye and planned to conquer Liaodong but failed due to Yi Pangwŏn’s coup. During the reign of T’aejong, Ming established Jianzhou Guard in Liaodong to control the Jurchens. While the Jurchens were embroiled in a dispute, King Sejong also established four districts and six garrisons and, he changed the geographical records from the previous dynasties and kingdoms to appear as if they had existed in the land south of the Amnok River in an attempt to protect the regions south of Amnok from the Ming invasion. This was recorded in Sejong sillok chiriji, Tongguk yŏji sŭngnam, and Koryŏsa.

  10. Missile Defense: Assessment of DODs Reports on Status of Efforts and Options for Improving Homeland Missile Defense

    Science.gov (United States)

    2016-02-17

    serving as an integrator and will need to weigh the pros and cons of competing for an integrator role vice a supplier role. In addition, shifting to an... YouTube . Subscribe to our RSS Feeds or E-mail Updates. Listen to our Podcasts . Visit GAO on the web at www.gao.gov. Contact: Website: www.gao.gov

  11. Nuclear Weapons Sustainment: Improvements Made to Budget Estimates Report, but Opportunities Remain to Further Enhance Transparency

    Science.gov (United States)

    2015-12-01

    Enhance Transparency Report to Congressional Committees December 2015 GAO-16-23 United States Government Accountability Office United...SUSTAINMENT Improvements Made to Budget Estimates Report, but Opportunities Remain to Further Enhance Transparency Why GAO Did This Study DOD and DOE are...modernization plans and (2) complete, transparent information on the methodologies used to develop those estimates. GAO analyzed the departments

  12. Veterans Justice Outreach Program: VA Could Improve Management by Establishing Performance Measures and Fully Assessing Risks

    Science.gov (United States)

    2016-04-01

    Assessing Risks Report to Congressional Requesters April 2016 GAO-16-393 United States Government Accountability Office United States...Government Accountability Office Highlights of GAO-16-393, a report to congressional requesters April 2016 VETERANS JUSTICE OUTREACH PROGRAM...quality, timeliness, efficiency, cost of service, and outcome. GAO, Tax Administration: IRS Needs to Further Refine Its Tax Filing Season

  13. A critical assessment of the microorganisms proposed to be important to enhanced biological phosphorus removal in full-scale wastewater treatment systems

    DEFF Research Database (Denmark)

    Stokholm-Bjerregaard, Mikkel; McIlroy, Simon Jon; Nierychlo, Marta

    2017-01-01

    accumulating organisms (PAOs). Also considered important to EBPR are the glycogen accumulating organisms (GAOs), which are theorized to compete with the PAOs for resources at the expense of P removal efficiency. Numerous studies have sought to identify the PAOs and their GAOs competitors, with several...... sequencing. The microbial community structure in all plants was relatively stable over time. Evidence for the role of the proposed PAOs and GAOs in EBPR varies and is critically assessed, in light of their calculated amplicon abundances, to indicate which of these are important in full-scale systems...... plants. Despite observed high abundances of GAOs (periodically exceeding 20% of the amplicon reads), P removal performance was maintained, indicating that these organisms were not outcompeting the PAOs in these EBPR systems. Phylogenetic diversity within each of the PAOs and GAOs genera was observed...

  14. Labor-Management Relations: Strikes and the Use of Permanent Strike Replacements in the 1970s and 1980s

    Science.gov (United States)

    1991-01-01

    Labor Violations Throughout the United States (GAO/HRD-90-i 16;, Apr. 30, 1990). Child Labor Violations and Sweatshops in the U.S. (GAO/T-11RD-90-18...Mar. 16,1990). How Well Does OSIIA Protect Workers From Reprisal: Inspector Opin- ions (GAO/T-HI1)-q0-8, Nov. 16, 1989). " Sweatshops " in the U.S

  15. Military Personnel: DOD Needs More Complete Data on Active-Duty Servicemembers Use of Food Assistance Programs

    Science.gov (United States)

    2016-07-01

    four installations that were selected based on size, cost of living, and presence of food assistance programs. What GAO Recommends GAO... criteria . In an April 2010 report, GAO identified 18 government programs that provide food assistance to low-income households. Servicemembers may apply...Vary 7 DOD Does Not Know the Extent to Which Servicemembers Use Food Assistance Programs 13 Military Officials at Selected Installations Cited

  16. Veterans’ Health Care: Limited Progress Made to Address Concerns That Led to High Risk Designation

    Science.gov (United States)

    2017-03-15

    Women Veterans. GAO-17-52. Washington , D.C.: December 2, 2016. Veterans Health Care: Improvements Needed in Operationalizing Strategic Goals and...Access to Primary Care. GAO-16-328. Washington , D.C.: March 18, 2016. DOD and VA Health Care: Actions Needed to Help Ensure Appropriate Medication...ET Wednesday, March 15, 2017 GAO-17-473T United States Government Accountability Office United States Government Accountability Office

  17. Nanoscale polysaccharide derivative as an AEG-1 siRNA carrier for effective osteosarcoma therapy

    Directory of Open Access Journals (Sweden)

    Wang F

    2018-02-01

    Full Text Available Fen Wang,1,* Jia-Dong Pang,2,* Lei-lei Huang,1 Ran Wang,1 Dan Li,3 Kang Sun,4 Lian-tang Wang,1,* Li-Ming Zhang2,* 1Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, 2PCFM Lab and GDHPPC Lab, School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, 3Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 4School of Engineering, Sun Yat-sen University, Guangzhou, China *These authors contributed equally to this work Background: Nanomedicine, which is the application of nanotechnology in medicine to make medical diagnosis and treatment more accurate, has great potential for precision medicine. Despite some improvements in nanomedicine, the lack of efficient and low-toxic vectors remains a major obstacle. Objective: The aim of this study was to prepare an efficient and low-toxic vector which could deliver astrocyte elevated gene-1 (AEG-1 small interfering RNA (siRNA; siAEG-1 into osteosarcoma cells effectively and silence the targeted gene both in vitro and in vivo. Materials and methods: We prepared a novel polysaccharide derivative by click conjugation of azidized chitosan with propargyl focal point poly (L-lysine dendrons (PLLD and subsequent coupling with folic acid (FA; Cs-g-PLLD-FA. We confirmed the complexation of siAEG-1and Cs-g-PLLD or Cs-g-PLLD-FA by gel retardation assay. We examined the cell cytotoxicity, cell uptake, cell proliferation and invasion abilities of Cs-g-PLLD-FA/siAEG-1 in osteosarcoma cells. In osteosarcoma 143B cells tumor-bearing mice models, we established the therapeutic efficacy and safety of Cs-g-PLLD-FA/siAEG-1. Results: Cs-g-PLLD-FA could completely encapsulate siAEG-1 and showed low cytotoxicity in osteosarcoma cells and tumour-bearing mice. The Cs-g-PLLD-FA/siAEG-1 nanocomplexes were capable of transferring siAEG-1 into osteosarcoma cells efficiently, and the knockdown of AEG-1

  18. Rural older people had lower mortality after accidental falls than non-rural older people

    Directory of Open Access Journals (Sweden)

    Huang JW

    2017-01-01

    Full Text Available Jen-Wu Huang,1,2 Yi-Ying Lin,2,3 Nai-Yuan Wu,4 Yu-Chun Chen5–7 1Department of Surgery, National Yang-Ming University Hospital, National Yang-Ming University, Yilan, Taiwan; 2Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 3Department of Pediatrics, Heping Fuyou Branch, Taipei City Hospital, Taipei, Taiwan; 4Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan; 5Department of Medical Research and Education, National Yang-Ming University Hospital, Yilan, Taiwan; 6Faculty of Medicine and School of Medicine, National Yang-Ming University, Taipei, Taiwan; 7Institute of Hospital and Health Care Administration, School of Medicine, National Yang-Ming University, Taipei, Taiwan Objective: This study aimed to investigate the mortality rate after falls of rural and non-rural older people and to explore the risk factors of mortality after falls among older people. Patients and methods: This population-based case–control study identified two groups from a nationwide claim database (National Health Insurance Research Database in Taiwan: a rural group and a non-rural group, which included 3,897 and 5,541 older people, respectively, who were hospitalized for accidental falls (The International Classification of Diseases, Ninth Revision, Clinical Modification: E880–E888 during 2006–2009. Both groups were followed up for 4 years after falls. Four-year cumulative all-cause mortality rate after falls was calculated, and the demographic factor, comorbidity, and medications were considered as the potential risk factors of mortality after falls. Results: The rural group had a significantly higher frequency of fall-related hospitalizations (7.4% vs 4.3%, P<0.001, but a lower 4-year cumulative all-cause mortality rate after falls than the non-rural group (8.8% vs 23.4%, P<0.001. After adjusting for age, gender, comorbidity, and medication use, the rural group had

  19. Degradable gene delivery systems based on Pluronics-modified low-molecular-weight polyethylenimine: preparation, characterization, intracellular trafficking, and cellular distribution

    Directory of Open Access Journals (Sweden)

    Ding X

    2012-02-01

    Full Text Available Wei Fan1,2,*, Xin Wu1,*, Baoyue Ding3,*, Jing Gao4, Zhen Cai1, Wei Zhang1, Dongfeng Yin1, Xiang Wang1, Quangang Zhu1, Jiyong Liu1, Xueying Ding4, Shen Gao1 1Department of Pharmaceutics, Changhai Hospital, Second Military Medical University, Shanghai, 2Department of Pharmaceutics, The 425th Hospital of PLA, Sanya, 3Department of Pharmaceutics, Medical College of Jiaxing University, Jiaxing, 4Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China*These authors contributed equally to this workBackground: Cationic copolymers consisting of polycations linked to nonionic amphiphilic block polymers have been evaluated as nonviral gene delivery systems, and a large number of different polymers and copolymers of linear, branched, and dendrimeric architectures have been tested in terms of their suitability and efficacy for in vitro and in vivo transfection. However, the discovery of new potent materials still largely relies on empiric approaches rather than a rational design. The authors investigated the relationship between the polymers' structures and their biological performance, including DNA compaction, toxicity, transfection efficiency, and the effect of cellular uptake.Methods: This article reports the synthesis and characterization of a series of cationic copolymers obtained by grafting polyethyleneimine with nonionic amphiphilic surfactant polyether-Pluronic® consisting of hydrophilic ethylene oxide and hydrophobic propylene oxide blocks. Transgene expression, cytotoxicity, localization of plasmids, and cellular uptake of these copolymers were evaluated following in vitro transfection of HeLa cell lines with various individual components of the copolymers.Results: Pluronics can exhibit biological activity including effects on enhancing DNA cellular uptake, nuclear translocation, and gene expression. The Pluronics with a higher hydrophilic-lipophilic balance value lead to

  20. MicroRNA-205 downregulates mixed-lineage-AF4 oncogene expression in acute lymphoblastic leukemia

    Directory of Open Access Journals (Sweden)

    Dou L

    2013-08-01

    Full Text Available Liping Dou,1,* Jingxin Li,1,* Dehua Zheng,2,* Yonghui Li,1 Xiaoning Gao,1 Chengwang Xu,1 Li Gao,1 Lili Wang,1 Li Yu1 1Department of Hematology, Chinese PLA General Hospital, Beijing, People's Republic of China; 2Department of Hepatobiliary Surgery, Organ Transplant Center, Chinese PLA 309th Hospital, Beijing, People's Republic of China*These authors contributed equally to this workAbstract: Myeloid/lymphoid or mixed-lineage AF4 acute lymphoblastic leukemia (MLL-AF4 ALL is a pediatric leukemia that occurs rarely in adults. MLL-AF4 ALL is typically characterized by the presence of chromosomal translocation (t(4;11(q21;q23, leading to expression of MLL-AF4 fusion protein. Although MLL-AF4 fusion protein triggers a molecular pathogenesis and hematological presentations that are unique to leukemias, the precise role of this oncogene in leukemogenesis remains unclear. Previous studies have indicated that microRNAs (miRs might modulate the expression of MLL-AF4 ALL fusion protein, thereby suggesting the involvement of miR in progression or suppression of MLL-AF4 ALL. We have previously demonstrated that miR-205 negatively regulates transcription of an MLL-AF4 luciferase reporter. Here, we report that exogenous expression of miR-205 in MLL-AF4 human cell lines (RS4;11 and MV4-11 inversely regulates the expression of MLL-AF4 at both messenger RNA (mRNA and protein level. Furthermore, miR-205 significantly induced apoptosis in MLL-AF4 cells as evidenced by Annexin V staining using fluorescence-activated cell sorting (FACS analysis. The proliferative capacity of leukemic cells was suppressed by miR-205. The addition of an miR-205 inhibitor was able to restore the observed effects. In conclusion, these findings demonstrate that miR-205 may have potential value as a novel therapeutic agent in the treatment of MLL-AF4 ALL.Keywords: miR-205, MLL-AF4, leukemia, microRNA, oncogene expression, untranslated regions, proliferation

  1. An Analysis of Internal Controls for DoD Contract Management

    Science.gov (United States)

    2015-12-01

    alternative control activities to reduce the risk of fraud ( COSO , 2013; GAO, 2014). Also, the Office of Management and Budget (OMB), which contains an...force. Since 1992, the Government Accountability Office (GAO) has identified contract management within the DOD as an area for high risk in fraud...force. Since 1992, the Government Accountability Office (GAO) has identified contract management within the DOD as an area for high risk in fraud

  2. Yan Sun, Corruption and Market in Contemporary China, Ithaca (N.Y.), Cornell University Press, 2004 et Ning Wang, Making a Market Economy. The Institutional Transformation of a Freshwater Fishery in a Chinese Community, Londres et New York, Routledge, 200

    OpenAIRE

    Guiheux, Gilles

    2008-01-01

    Ces deux ouvrages éclairent les conditions dans lesquelles, au cours des 25 dernières années, l’économie de commande a été démantelée et remplacée progressivement par un système de marché. Yan Sun, professeur de sciences politiques, s’intéresse à la corruption dans une double perspective macro et micro. Ning Wang, économiste néo-institutionnaliste, se demande comment, à la faveur des réformes, une région (Jingzhou, au sud du Hubei) s’est convertie à la pisciculture. La corruption est une ques...

  3. Denitrifying capability and community dynamics of glycogen accumulating organisms during sludge granulation in an anaerobic-aerobic sequencing batch reactor

    Science.gov (United States)

    Bin, Zhang; Bin, Xue; Zhigang, Qiu; Zhiqiang, Chen; Junwen, Li; Taishi, Gong; Wenci, Zou; Jingfeng, Wang

    2015-08-01

    Denitrifying capability of glycogen accumulating organisms (GAOs) has received great attention in environmental science and microbial ecology. Combining this ability with granule processes would be an interesting attempt. Here, a laboratory-scale sequencing batch reactor (SBR) was operated to enrich GAOs and enable sludge granulation. The results showed that the GAO granules were cultivated successfully and the granules had denitrifying capability. The batch experiments demonstrated that all NO3--N could be removed or reduced, some amount of NO2--N were accumulated in the reactor, and N2 was the main gaseous product. SEM analysis suggested that the granules were tightly packed with a large amount of tetrad-forming organisms (TFOs); filamentous bacteria served as the supporting structures for the granules. The microbial community structure of GAO granules was differed substantially from the inoculant conventional activated sludge. Most of the bacteria in the seed sludge grouped with members of Proteobacterium. FISH analysis confirmed that GAOs were the predominant members in the granules and were distributed evenly throughout the granular space. In contrast, PAOs were severely inhibited. Overall, cultivation of the GAO granules and utilizing their denitrifying capability can provide us with a new approach of nitrogen removal and saving more energy.

  4. Effects of 90-day feeding of transgenic Bt rice TT51 on the reproductive system in male rats.

    Science.gov (United States)

    Wang, Er Hui; Yu, Zhou; Hu, Jing; Xu, Hai Bin

    2013-12-01

    Rice is a staple food crop; however, the threat of pests leads to a serious decline in its output and quality. The CryAb/CryAc gene, encodes a synthetic fusion Bacillus thuringiensis (Bt) crystal protein, was introduced into rice MingHui63 to produce insect-resistant rice TT51. This study was undertaken to investigate potential unintended effects of TT51 on the reproductive system in male rats. Male rats were treated with diets containing 60% of either TT51 or MingHui63 by weight, nutritionally balanced to an AIN93G diet, for 90days. An additional negative control group of rats were fed with a rice-based AIN93G diet. Body weights, food intake, hematology, serum chemistry, serum hormone levels, sperm parameters and relative organ/body weights were measured, and gross as well as microscopic pathology were examined. No diet-related significant differences in the values of response variables were observed between rats that were fed with diet containing transgenic TT51, MingHui63 and the control in this 90-day feeding study. In addition, necropsy and histopathology examination indicated no treatment-related changes. The results from the present study indicated that TT51 does not appear to exert any effect on the reproductive system in male rats compared with MingHui63 or the control. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Business Systems Modernization: DOD Needs to Fully Define Policies and Procedures for Institutionally Managing Investments

    National Research Council Canada - National Science Library

    Hite, Randolph C; Doherty, Neil; Fraser, Nalani; Glover, Nancy; Holland, Michael; Lakhmani, Neelaxi; Mai, Jacqueline; Paul, Sabine; Tandon, Niti; Stavros-Turner, Jennifer

    2007-01-01

    ... (IT) business system investment management. To support GAO's legislative mandate to review DoD's efforts, GAO assessed whether the department's corporate investment management approach comports with relevant federal guidance...

  6. Taxonomic review on the subgenus Tripodura Townes (Diptera: Chironomidae: Polypedilum) from China with eleven new species and a supplementary world checklist.

    Science.gov (United States)

    Zhang, Ruilei; Song, Chao; Qi, Xin; Wang, Xinhua

    2016-07-05

    The subgenus Tripodura Townes of Polypedilum Kieffer from China including 26 species is reviewed. Eleven new species, named P. (T.) absensilobum Zhang & Wang sp. n., P. (T.) apiculusetosum Zhang & Wang sp. n., P. (T.) arcuatum Zhang & Wang sp. n., P. (T.) bilamella Zhang & Wang sp. n., P. (T.) conghuaense Zhang & Wang sp. n., P. (T.) dengae Zhang & Wang sp. n., P. (T.) mengmanense Zhang & Wang sp. n., P. (T.) napahaiense Zhang & Wang sp. n., P. (T.) parallelum Zhang & Wang sp. n., P. (T.) pollicium Zhang & Wang sp. n. and P. (T.) trapezium Zhang & Wang sp. n. are described and illustrated based on male imagines. Three species, P. (T.) quadriguttatum Kieffer, P. (T.) unifascia (Tokunaga) and P. (T.) udominutum Niitsuma are firstly recorded in China. A key to known male imagines of Chinese species and an updated world checklist of subgenus Tripodura are presented.

  7. Absorption of SO/sub 2/ by pecan (Carya illinoensis (Wang) K. Koch) and alfalfa (Medicago sativa L. ) and its effect on net photosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Sisson, W.B.; Booth, J.A.; Throneberry, G.O.

    1981-06-01

    Absorption rates of SO/sub 2/ by pecan (Carya illinoensis (Wang) K. Koch) leaflets exposed to 2.6, 5.2, and 7.8 mg SO/sub 2/ m/sup -3/ were measured over a 2 h period. SO/sub 2/ was rapidly absorbed by the leaflets in all treatments during the initial 30-50 min; the rate of uptake decreased to a rather constant level thereafter. Total SO/sub 2/ absorbed during the 2 h period was 15.6, 25.6, and 38.9 nmol cm/sup -2/ for the low, medium, and high SO/sub 2/ concentrations, respectively. Reductions in net photosynthetic rates were proportional to ambient SO/sub 2/ concentrations and total SO/sub 2/ absorbed. Partial photosynthetic recovery occurred in all treatments during a 2 hr post-treatment period and full recovery occurred during a 12 h dark period. Exposure to SO/sub 2/ resulted in slight increases in stomatal and boundary layer resistances to CO/sub 2/ and substantial increases in residual resistances. Absorption rates of SO/sub 2/ by alfalfa (Medicago sativa L.) exposed to 5.2 mg SO/sub 2/ m/sup -3/ for 1 h were approximately double those of pecan exposed to the same ambient SO/sub 2/ concentration. Alfalfa net photosynthetic rates were reduced 74% after 1 h exposure to 5.2 mg SO/sub 2/ m/sup -3/ while a depression of 42% occurred in pecan.

  8. Analisis senyawa volatil dari ekstrak tanaman yang berpotensi sebagai atraktan parasitoid telur wereng batang coklat, Anagrus nilaparvatae (Pang et Wang (Hymenoptera: Mymaridae

    Directory of Open Access Journals (Sweden)

    Surjani Wonorahardjo

    2015-09-01

    Full Text Available Plants produce volatiles as communication cues intra- or inter- species. Infested plants by herbivores will produce volatiles as indirect defense mechanism that attracts natural enemies of herbivores. Analysis of volatiles compounds produced by rice plant as result of infested brown plant hopper (BPH, Nilaparvata lugens Stâl, was done to identify compounds in the volatiles that potentially can be used as attractant for egg parasitoids of BPH, Anagrus nilaparvatae (Pang et Wang (Hymenoptera: Mymaridae. This research was an early stage to develop formulation of parasitoid attractant. The research activities include volatiles extraction of infested rice stem by BPH eggs using acetone, n-hexane as the extraction solvents; analyses of volatile compounds with GC-MS; and bioassay of parasitoid orientation behavior to the volatiles using olfactometer methods. Extraction methods applied were maceration and continuous extraction followed by concentration. Bioassay on the parasitoid orientation behavior was done by using Y-tube olfactometer and every lot of bioassay using 30 parasitoid females with 3 replicates. The results showed that the volatile compounds of extract of infested rice stem by BPH eggs comprise of 16 components. The highest proportion of the components extracted with acetone is 2-Pentanone, 4-hydroxy-4-methyl (19,9%, while those with n-hexane is Hexanedioic acid, dioctyl ester (65%. A. nilaparvatae showed positive response to the volatiles extracted from infested rice plant by N. lugens eggs. Therefore, the volatiles can be used as an attractant for the egg A. nilaparvatae to support rice pest management.

  9. Human Capital: Additional Actions Needed to Enhance DOD’s Efforts to Address Mental Health Care Stigma

    Science.gov (United States)

    2016-04-01

    Civilians (n=21) 6 5 8 2 h) Substance abuse (alcohol or drugs ) Servicemembers (n= 186) 43 53 82 8 Civilians (n=22) 9 8 4 1 Source: GAO | GAO...Efforts to Address Mental Health Care Stigma Why GAO Did This Study A 2010 DOD task force on suicide prevention concluded that stigma—the negative...Representatives A 2010 Department of Defense (DOD) Task Force on the Prevention of Suicide by Members of the Armed Forces concluded that

  10. Littoral Combat Ship and Frigate: Slowing Planned Frigate Acquisition Would Enable Better Informed Decisions

    Science.gov (United States)

    2016-12-08

    weld seam from tugboat LCS 8 October 2016 Hull damage during Panama Canal transit Source: GAO analysis of Navy documentation. | GAO-17-279T However...these types of major incidents are not limited to the past 12 months. For example, LCS 4 also rubbed against the sides of the Panama Canal locks...Connect with GAO To Report Fraud, Waste, and Abuse in Federal Programs Congressional Relations Public Affairs Strategic Planning and External Liaison Please Print on Recycled Paper .

  11. [The affinity between Le family of Tong Ren Tang and acu-moxibustion as viewed from Mian xue tang zhen jiu ji cheng (Mian Xuetang's Synthetic Work of Acu-moxibustion)].

    Science.gov (United States)

    Huang, L X

    2017-11-28

    This compilation process of Mian xue tang zhen jiu ji cheng ( Mian Xuetang ' s Synthetic Work of Acu - moxibustion )was quite mysterious, the book's advent coincidentally met with several major historical events which made its value of decoding its historical functions far beyond its academic value. The editor of this book is Le Xianyang, the founder of Tong Ren Tang. While compiling this book, he also made a replica of Ming-Dynasty's Zhengtong bronze statue. More than 200 years later, Le Jingyu, the 12th generation of the Le family revised Ming Tang Tu inherited from his ancestors and engraved Ming Tang Tu on the stone for its standardization. This great achievement of Le family was no less than the recasting of the Tiansheng bronze statue and the reengraving Tong ren shu xue zhen jiu tu jing ( Illustrated Manual of Acupuncture Points of the Bronze Figure ) by support of state power for building the Beijing Imperial Hospital in the eighth year of the Zhengtong reign (1443).

  12. 75 FR 71567 - Public Availability of Government Accountability Office Records

    Science.gov (United States)

    2010-11-24

    ... the GAO Forensic Audits and Special Investigations (GAO FraudNet) are an example of records that could... occasionally collects, during the course of its audits and investigations, records from law enforcement...

  13. Defense Acquisitions. Missile Defense Needs a Better Balance between Flexibility and Accountability

    National Research Council Canada - National Science Library

    Francis, Paul

    2007-01-01

    .... Congress requires GAO to assess MDA's progress annually. GAO's March 2007 report addressed MDA's progress during fiscal year 2006 and followed up on program oversight issues and the current status of MDA's quality assurance program...

  14. Military Operations: DOD Needs to Address Contract Oversight and Quality Assurance Issues for Contracts Used to Support Contingency Operations

    National Research Council Canada - National Science Library

    Solis, William M; Coffey, Carole; Baker, Sarah; Brown, Renee; Junek, Larry; La Due Lake, Ronald; Lenane, Katherine; Mason, Susan; Sawyer, Jr., Connie W; Thornton, Karen

    2008-01-01

    .... In its fiscal year 2007 report, the House Appropriations Committee directed GAO to examine the link between the growth in DOD's operation and maintenance costs and DOD's increased reliance on service contracts. GAO determined (1...

  15. FISCAL YEAR 2003 BUDGET REQUEST. U.S. General Accounting Office

    National Research Council Canada - National Science Library

    2002-01-01

    .... General Accounting Office (GAO) to report on GAO's fiscal year 2001 performance and results, current challenges and future plans, and budget request for fiscal year 2003 to support the Congress and serve the American public...

  16. A novel preparation method for drug nanocrystals and characterization by ultrasonic spray assisted electrostatic adsorption

    Directory of Open Access Journals (Sweden)

    Gao B

    2013-10-01

    Full Text Available Bing Gao,1–3 Jun Wang,2 Dunju Wang,1,2 Ziqiang Zhu,1,2 Zhiqiang Qiao,2 Guangcheng Yang,2 Fude Nie21School of Material Science and Engineering, Southwest University of Science and Technology, Mianyang, People's Republic of China, 2Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang, Sichuan, People's Republic of China, 3Si Chuan Research Center of New Materials, Mianyang, People's Republic of ChinaPurpose: The purpose of this study was to develop a novel and continuous method for preparing a nanosized particle of drug crystals and to characterize its properties.Materials and methods: A new apparatus was introduced to crystallize nanosized drug crystals of amitriptyline hydrochloride as a model drug. The samples were prepared in the pure state by ultrasonic spray, and elaborated deposition was completed via electrostatic adsorption. Scanning electron microscopy, X-ray powder diffraction, and atomic force microscopy were used to characterize the size of the particles; this was subsequently followed by differential scanning calorimetry.Results and discussion: Nanoparticles of drug crystals were successfully prepared. The size of the drug crystals ranged from 20 nm to 400 nm; the particle size of amitriptyline hydrochloride was approximately 71 nm. The particles were spherical and rectangular in shape. Moreover, the melting point of the nanoparticles decreased from 198.2°C to 196.3°C when compared to raw particle crystals. Furthermore, the agglomeration effect was also attenuated as a result of electrostatic repulsion among each particle when absorbed, and depositing on the inner wall of the gathering unit occurred under the electrostatic effect.Conclusion: Ultrasonic spray-assisted electrostatic adsorption is a very effective and continuous method to produce drug nanocrystals. This method can be applied to poorly water-soluble drugs, and it can also be a very effective alternative for industrial production. Once the

  17. The 2nd International Conference on Water Resource and Environment (WRE 2016

    Directory of Open Access Journals (Sweden)

    Zhouli Liu

    2016-11-01

    Full Text Available Table of contents 01 The eco-toxicological effects of cadmium stress on five ornamental plants Zhouli Liu, Wei Chen, Xingyuan He, Shuai Yu, Weihang Ding 02 Study on the formation and release mechanisms of hydrogen sulfide in Longtan coal mine Jianjun Liu, Yuliang Wu, Kaixiang Fan 03 Coral bleaching in the North Reef of China’s Xisha Islands in 2014 Yuanchao Li, Xinqing Zheng, Shiquan Chen, Haiqun Xie 04 Soil chemical characteristics in a Cunninghamia lanceolata stand suffering from ice-snow damage Jie Li, Zhuomin Wang, Li Xue 05 Diversity of understory vegetation was under a Cunninghamia lanceolata stand suffering from ice-snow damage Zhiyang Lie, Weilong Huang, Tongtong Zhou, Li Xue 06 The effect of water, nitrogen and harvesting time on yield and biomass allocation of Helianthus tuberosus L. Kai Gao, Tiexia Zhu 07 The vertical variation of microbial communities in the sediment of sea cucumber pond Weiteng Mao, Pei Yu, Xinfang Lv, Yunchun Li 08 Indicating significances of alpine plant functional groups to environmental change Peixi Su, Rui Shi 09 Research on the daily CH4 fluxes of soil in summer mangrove community at Yingluogang of Guangxi, China Yong Jiang, Xingbin Chen, Shichu liang 10 Beach protection structures in middle and lower reaches of Yangtze River Junfeng Xu 11 Social responsibility management of large dam project with owner as core: an empirical case in China Jiwei Zhu, Zhao Zhai, Linan Zhou, Yun Le, Li Cao 12 The ecological function value assessment analysis of urban waterfront Jiwei Zhu, Ping Lu, Zhiqian Huang, Bei Zhou 13 Mechanism of diurnal osmotic potential changes and adjustment of three Caragana species in different habitats of the Inner Mongolia Plateau Zhirong Zheng, Shihai Lv, Chaoyang Feng 14 Biodiversity of phytoplankton and environmental influences analysis of Longfeng Wetland, China Nan Song, Yan Liu, Xinxin Lu, Yawen Fan 15 The effect of human activities on culturable soil microbes from Yaoquan Mountain in

  18. Non-destructive analysis and appraisal of ancient Chinese porcelain by PIXE

    International Nuclear Information System (INIS)

    Cheng, H.S.; Zhang, Z.Q.; Xia, H.N.; Jiang, J.C.; Yang, F.J.

    2002-01-01

    This paper reports the results of the PIXE analysis on ancient Chinese blue and white porcelain fired at Kuan Kiln (Jingdezhen, Jiangxi province) during 13-19th century. The major, minor and trace element of porcelain body, white glaze and blue glaze were determined by PIXE. In this paper the chemical compositions of porcelain body, white glaze and blue glaze measured from Yuan (AD 1206-1368), Ming (AD 1368-1644) and Qing (AD 1616-1911) blue and white porcelain are present. The cobalt blue pigment used in Yuan, Ming and Qing are also discussed

  19. International Conference on the Physics of Electronic and Atomic Collisions (14th) Held in Palo Alto, California on 24-30 July 1985 (Electronic and Atomic Collisions. Invited Papers)

    Science.gov (United States)

    1985-07-30

    76] A. Zastawny, Acta . Phys. Polonica , A46 (1974) 39. 77] R. GrUnberg, Z. Naturforsch., A24 (169) 1039. 78] R. Grnberg, Z. Naturforsch., A 3 (1978...Rev. A12 (1975) 1825. 24) A.K. Pradhan, Phys. Rev. Lett. 32 (1983) 84. 47 (1981) 79. 25) Jia-Ming Li(C.M. Lee), Acta Physica Sinica 32 (1983) 84. 26...1985) XXX. 33) H. Bethe, Ann. Physik 5(1930) 325. 34) M. Inokuti, Rev. Mod. Phys. 43 (1971) 279. 35) Bo-Cang Tian, Jia-Ming Li(C.M. Lee), Acta Physica

  20. Non-destructive analysis and appraisal of ancient Chinese porcelain by PIXE

    Science.gov (United States)

    Cheng, H. S.; Zhang, Z. Q.; Xia, H. N.; Jiang, J. C.; Yang, F. J.

    2002-05-01

    This paper reports the results of the PIXE analysis on ancient Chinese blue and white porcelain fired at Kuan Kiln (Jingdezhen, Jiangxi province) during 13-19th century. The major, minor and trace element of porcelain body, white glaze and blue glaze were determined by PIXE. In this paper the chemical compositions of porcelain body, white glaze and blue glaze measured from Yuan (AD 1206-1368), Ming (AD 1368-1644) and Qing (AD 1616-1911) blue and white porcelain are present. The cobalt blue pigment used in Yuan, Ming and Qing are also discussed.

  1. Stereotactic body radiation therapy via helical tomotherapy to replace brachytherapy for brachytherapy-unsuitable cervical cancer patients – a preliminary result

    Directory of Open Access Journals (Sweden)

    Hsieh CH

    2013-02-01

    Full Text Available Chen-Hsi Hsieh,1–3 Hui-Ju Tien,1 Sheng-Mou Hsiao,4 Ming-Chow Wei,4 Wen-Yih Wu,4 Hsu-Dong Sun,4 Li-Ying Wang,5 Yen-Ping Hsieh,6 Yu-Jen Chen,3,7–9 Pei-Wei Shueng1,101Department of Radiation Oncology, Far Eastern Memorial Hospital, Taipei, Taiwan; 2Department of Medicine, 3Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 4Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, Taipei, Taiwan; 5School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan; 6Department of Senior Citizen Service Management, National Taichung University of Science and Technology, Taichung, Taiwan; 7Department of Radiation Oncology, 8Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; 9Graduate Institute of Sport Coaching Science, Chinese Culture University, Taipei, Taiwan; 10Department of Radiation Oncology, National Defense Medical Center, Taipei, TaiwanAim: To review the experience and to evaluate the results of stereotactic body radiation therapy (SBRT via helical tomotherapy (HT, for the treatment of brachytherapy-unsuitable cervical cancer.Methods: Between September 1, 2008 to January 31, 2012, nine cervical cancer patients unsuitable for brachytherapy were enrolled. All of the patients received definitive whole pelvic radiotherapy with or without chemotherapy, followed by SBRT via HT.Results: The actuarial locoregional control rate at 3 years was 78%. The mean biological equivalent dose in 2-Gy fractions of the tumor, rectum, bladder, and intestines was 76.0 ± 7.3, 73.8 ± 13.2, 70.5 ± 10.0, and 43.1 ± 7.1, respectively. Only two had residual tumors after treatment, and the others were tumor-free. Two patients experienced grade 3 acute toxicity: one had diarrhea; and another experienced thrombocytopenia. There were no grade 3 or 4 subacute toxicities. Three patients suffered from manageable rectal bleeding in

  2. Partial stereotactic ablative boost radiotherapy in bulky non-small cell lung cancer: a retrospective study

    Directory of Open Access Journals (Sweden)

    Bai Y

    2018-05-01

    Full Text Available Yun Bai,1 Xian-shu Gao,1 Shang-bin Qin,1 Jia-yan Chen,1 Meng-meng Su,1 Qing Liu,2 Xiu-bo Qin,2 Ming-wei Ma,1 Bo Zhao,1 Xiao-bin Gu,1 Mu Xie,1 Ming Cui,1 Xin Qi,1 Xiao-ying Li1 1Department of Radiation Oncology, Peking University First Hospital, Beijing, China; 2Department of Medical Imaging, Peking University First Hospital, Beijing, China Purpose: Bulky non-small cell lung cancer (NSCLC is difficult to achieve effective local control by conventionally fractionated radiotherapy (CRT. The present work aims to evaluate the safety and efficacy of partial stereotactic ablative boost radiotherapy (P-SABR in bulky NSCLC. Patients and methods: From December 2012 through August 2017, 30 patients with bulky NSCLC treated with P-SABR technique were analyzed. The P-SABR plan consisted of one partial SABR plan (5–9 Gy/f, 3–6 fractions to gross tumor boost (GTVb, followed by one CRT plan to the planning target volume (PTV. GTVb was the max volume receiving SABR to guarantee the dose of organs-at-risks (OARs falloff to about 3 Gy/f. The total dose of PTV margin was planned to above 60 Gy. The simply CRT plans were created using the same planning parameters as the original plan, with the goal to achieve comparable OARs doses and PTV margin dose to the P-SABR plan. Dosimetric variables were acquired in both P-SABR and compared CRT plans. Toxicity, local control, and survival were also evaluated. Results: Median follow-up in survivors was 10.3 months (range=2.3–39.4 months. Eleven patients (36.7% had partial response (PR and ten patients (33.3% had stable disease (SD. Two-year overall survival was 55.6%. Two-year local control rate was 85.7%. No severe acute side effects .CTCAE Grade III were observed. Compared to the simply CRT plan, P-SABR plans achieved similar doses to the OARs and Dmin, but increased dose at the isocenter, Dmean, Dmax, and biological equivalent dose (BED significantly (P<0.05. BED in the tumor center could reach 107.3 Gy (93.2–132

  3. 77 FR 27774 - Health Information Technology Policy Committee Vacancy

    Science.gov (United States)

    2012-05-11

    ... GOVERNMENT ACCOUNTABILITY OFFICE Health Information Technology Policy Committee Vacancy AGENCY... American Recovery and Reinvestment Act of 2009 (ARRA) established the Health Information Technology Policy.... ADDRESSES: GAO: [email protected] . GAO: 441 G Street NW., Washington, DC 20548. FOR FURTHER INFORMATION...

  4. Developmental immunotoxicity is not associated with the consumption of transgenic Bt rice TT51 in rats.

    Science.gov (United States)

    Hu, Jing; Liang, Chunlai; Zhang, Xiaopeng; Zhang, Qiannan; Cui, Wenming; Yu, Zhou

    2018-04-01

    TT51 is a transgenic strain of Bt rice generated by fusing a synthetic CryAb/Ac gene into MingHui rice. In this study, rats from F0, F1, and F2 generations were fed a diet with 60% TT51 rice, MingHui rice, or nominal-origin rice. The study focused on developmental immunotoxicity in F1 and F2 offspring after long-term consumption of TT51. A wide range of immunological parameters was monitored in this two-generation study on reproductive toxicity. The experiments were performed on F1 and F2 offspring at postnatal days 21 and 42. No adverse clinical effects were observed in any of the experimental groups. In addition, histopathology observations and immunotoxicity tests, including hematological indicators, spleen lymphocyte subsets, natural killer cell activity, lymphoproliferative response, and plaque-forming cell assay, revealed no significant difference between the groups. These results indicated that developmental immunotoxicity was not associated with a diet of transgenic Bt rice TT51, compared to the parental MingHui rice. Copyright © 2018 Elsevier Inc. All rights reserved.

  5. Defense Budget: DOD Needs to Improve Reporting of Operation and Maintenance Base Obligations

    Science.gov (United States)

    2016-08-01

    10For additional information on DOD’s planning, programming, budgeting, and execution process, see GAO, DOD Service Acquisition ...check, or money order. Call for additional information. Connect with GAO on Facebook , Flickr, Twitter, and YouTube. Subscribe to our RSS Feeds or E

  6. Topological phase transition in the two-dimensional anisotropic Heisenberg model: A study using the Replica Exchange Wang-Landau sampling

    Science.gov (United States)

    Figueiredo, T. P.; Rocha, J. C. S.; Costa, B. V.

    2017-12-01

    Although the topological Berezinskii-Kosterlitz-Thouless transition was for the first time described by 40 years ago, it is still a matter of discussion. It has been used to explain several experiments in the most diverse physical systems. In contrast with the ordinary continuous phase transitions the BKT-transition does not break any symmetry. However, in some contexts it can easily be confused with other continuous transitions, in general due to an insufficient data analysis. The two-dimensional XY (or sometimes called planar rotator) spin model is the fruit fly model describing the BKT transition. As demonstrated by Bramwell and Holdsworth (1993) the finite-size effects are more important in two-dimensions than in others due to the logarithmic system size dependence of the properties of the system. Closely related is the anisotropic two dimensional Heisenberg model (AH). Although they have the same Hamiltonian the spin variable in the former has only two degrees of freedom while the AH has three. Many works treat the AH model as undergoing a transition in the same universality class as the XY model. However, its characterization as being in the BKT class of universality deserve some investigation. This paper has two goals. First, we describe an analytical evidence showing that the AH model is in the BKT class of universality. Second, we make an extensive simulation, using the numerical Replica Exchange Wang-Landau method that corroborate our analytical calculations. From our simulation we obtain the BKT transition temperature as TBKT = 0 . 6980(10) by monitoring the susceptibility, the two point correlation function and the helicity modulus. We discuss the misuse of the fourth order Binder's cumulant to locate the transition temperature. The specific heat is shown to have a non-critical behavior as expected in the BKT transition. An analysis of the two point correlation function at low temperature, C(r) ∝r - η(T), shows that the exponent, η, is consistent

  7. Petrochemistry and zircon U-Pb geochronology of granitic rocks in the Wang Nam Khiao area, Nakhon Ratchasima, Thailand: Implications for petrogenesis and tectonic setting

    Science.gov (United States)

    Fanka, Alongkot; Tsunogae, Toshiaki; Daorerk, Veerote; Tsutsumi, Yukiyasu; Takamura, Yusuke; Sutthirat, Chakkaphan

    2018-05-01

    Carboniferous biotite granite, Late Permian hornblende granite, and Triassic biotite-hornblende granite, all of which belong to the Eastern Granite Belt, expose in the Wang Nam Khiao area, Nakhon Ratchasima, northeastern Thailand. The Carboniferous biotite granite is dominated by quartz, K-feldspar, plagioclase, and biotite. The Late Permian hornblende granite contains dominant assemblages of plagioclase, quartz, K-feldspar, hornblende, and minor amount of biotite, while the Triassic biotite-hornblende granite consists of quartz, plagioclase, K-feldspar with small amounts of biotite, and hornblende. The REE patterns with steep decrease from light to heavy REE together with the LILE (e.g. K, Sr) enrichment and depletion of some particular HFSE (e.g. Nb, Ti) indicate low degree of partial melting. Mineral chemistry of biotite and hornblende in the granites reflects crystallization from hydrous calc-alkaline arc-derived magmas possibly formed by subduction. Amphibole-plagioclase thermometry and Al-in-hornblende barometry indicate that the Late Permian hornblende granite and the Triassic biotite-hornblende granite may have equilibrated at 3.0-5.8 kbar/700-820 °C and 2.0-3.2 kbar/600-750 °C, respectively, in the middle-upper crust (about 10-15 km depth). Zircon U-Pb geochronology of the Carboniferous biotite granite, Late Permian hornblende granite and Triassic biotite-hornblende granite yielded intrusion ages of 314.6-284.9 Ma, 253.4 Ma, and 237.8 Ma, respectively, which implies multiple episodes of arc-magmatism formed by Palaeo-Tethys subduction beneath Indochina Terrane during Late Carboniferous/Early Permian, Late Permian and Middle Triassic.

  8. Population dynamics of bacteria involved in enhanced biological phosphorus removal in Danish wastewater treatment plants.

    Science.gov (United States)

    Mielczarek, Artur Tomasz; Nguyen, Hien Thi Thu; Nielsen, Jeppe Lund; Nielsen, Per Halkjær

    2013-03-15

    The enhanced biological phosphorus removal (EBPR) process is increasingly popular as a sustainable method for removal of phosphorus (P) from wastewater. This study consisted of a comprehensive three-year investigation of the identity and population dynamics of polyphosphate-accumulating organisms (PAOs) and glycogen-accumulating organisms (GAOs) in 28 Danish municipal wastewater treatment plants with nutrient removal. Fluorescence in situ hybridization was applied to quantify ten probe-defined populations of PAO and GAO that in total constituted a large fraction (30% on average) of the entire microbial community targeted by the EUBmix probes. Two PAO genera, Accumulibacter and Tetrasphaera, were very abundant in all EBPR plants (average of 3.7% and 27% of all bacteria, respectively), and their abundance was relatively stable in the Danish full-scale plants without clear temporal variations. GAOs were occasionally present in some plants (Competibacter in 11 plants, Defluviicoccus in 6 plants) and were consistent in only a few plants. This shows that these were not core species in the EBPR communities. The total GAO abundance was always lower than that of Accumulibacter. In plants without EBPR design, the abundance of PAO and GAO was significantly lower. Competibacter correlated in general with high fraction of industrial wastewater. In specific plants Accumulibacter correlated with high C/P ratio of the wastewater and Tetrasphaera with high organic loading. Interestingly, the relative microbial composition of the PAO/GAO species was unique to each plant over time, which gives a characteristic plant-specific "fingerprint". Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Federal Employees’ Compensation Act: DOD Access to DOL Data is Generally Sufficient, but Monitoring Timelines Could Help Return-to-Work Efforts

    Science.gov (United States)

    2016-09-01

    including reimbursement for transportation costs incurred in obtaining medical treatment or rehabilitation services, or nursing and other...Flickr, Twitter, and YouTube . Subscribe to our RSS Feeds or E-mail Updates. Listen to our Podcasts. Visit GAO on the web at www.gao.gov. Contact

  10. “Candidatus Propionivibrio aalborgensis”

    DEFF Research Database (Denmark)

    Albertsen, Mads; McIlroy, Simon Jon; Stokholm-Bjerregaard, Mikkel

    2016-01-01

    by wasting the biomass. However, glycogen accumulating organisms (GAOs) may reduce the EBPR efficiency as they compete for substrates with PAOs, but do not store excessive amounts of polyphosphate. PAOs and GAOs are thought to be phylogenetically unrelated, with the model PAO being the betaproteobacterial...

  11. Improving the security of a quantum secret sharing protocol between multiparty and multiparty without entanglement

    International Nuclear Information System (INIS)

    Han Lianfang; Liu Yimin; Shi Shouhua; Zhang Zhanjun

    2007-01-01

    Recently Yan and Gao [F.L. Yan, T. Gao, Phys. Rev. A 72 (2005) 012304] have proposed a quantum secret sharing protocol which allows a secret message to be shared between one group of m parties and another group of n parties. The protocol is claimed to be secure. In this Letter, first we show that any subgroup consisting of evil cooperative parties (or one and only one evil party) can successfully cheat other parties to obtain the secret message without being detected. Then we improve the original Yan-Gao protocol such that the insider's cheats are prevented

  12. Evolved Expendable Launch Vehicle: DOD Is Assessing Data on Worldwide Launch Market to Inform New Acquisition Strategy

    Science.gov (United States)

    2016-07-22

    order. Call for additional information. Connect with GAO on Facebook , Flickr, Twitter, and YouTube. Subscribe to our RSS Feeds or E-mail Updates...Phone Connect with GAO To Report Fraud , Waste, and Abuse in Federal Programs Congressional Relations Public Affairs Please Print on Recycled Paper.

  13. The application of hyaluronic acid-derivatized carbon nanotubes in hematoporphyrin monomethyl ether-based photodynamic therapy for in vivo and in vitro cancer treatment

    Directory of Open Access Journals (Sweden)

    Shi J

    2013-07-01

    Full Text Available Jinjin Shi,* Rourou Ma,* Lei Wang, Jing Zhang, Ruiyuan Liu, Lulu Li, Yan Liu, Lin Hou, Xiaoyuan Yu, Jun Gao, Zhenzhong Zhang School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, People's Republic of China*These authors contributed equally to this workAbstract: Carbon nanotubes (CNTs have shown great potential in both photothermal therapy and drug delivery. In this study, a CNT derivative, hyaluronic acid-derivatized CNTs (HA-CNTs with high aqueous solubility, neutral pH, and tumor-targeting activity, were synthesized and characterized, and then a new photodynamic therapy agent, hematoporphyrin monomethyl ether (HMME, was adsorbed onto the functionalized CNTs to develop HMME-HA-CNTs. Tumor growth inhibition was investigated both in vivo and in vitro by a combination of photothermal therapy and photodynamic therapy using HMME-HA-CNTs. The ability of HMME-HA-CNT nanoparticles to combine local specific photodynamic therapy with external near-infrared photothermal therapy significantly improved the therapeutic efficacy of cancer treatment. Compared with photodynamic therapy or photothermal therapy alone, the combined treatment demonstrated a synergistic effect, resulting in higher therapeutic efficacy without obvious toxic effects to normal organs. Overall, it was demonstrated that HMME-HA-CNTs could be successfully applied to photodynamic therapy and photothermal therapy simultaneously in future tumor therapy.Keywords: photodynamic therapy, photothermal therapy, HA-derivatized carbon nanotubes, tumor targeting, synergistic effect, hematoporphyrin monomethyl ether

  14. A Critical Assessment of the Microorganisms Proposed to be Important to Enhanced Biological Phosphorus Removal in Full-Scale Wastewater Treatment Systems.

    Science.gov (United States)

    Stokholm-Bjerregaard, Mikkel; McIlroy, Simon J; Nierychlo, Marta; Karst, Søren M; Albertsen, Mads; Nielsen, Per H

    2017-01-01

    Understanding the microbiology of phosphorus (P) removal is considered essential to knowledge-based optimization of enhanced biological P removal (EBPR) systems. Biological P removal is achieved in these systems by promoting the growth of organisms collectively known as the polyphosphate accumulating organisms (PAOs). Also considered important to EBPR are the glycogen accumulating organisms (GAOs), which are theorized to compete with the PAOs for resources at the expense of P removal efficiency. Numerous studies have sought to identify the PAOs and their GAOs competitors, with several candidates proposed for each over the last few decades. The current study collectively assessed the abundance and diversity of all proposed PAOs and GAOs in 18 Danish full-scale wastewater treatment plants with well-working biological nutrient removal over a period of 9 years using 16S rRNA gene amplicon sequencing. The microbial community structure in all plants was relatively stable over time. Evidence for the role of the proposed PAOs and GAOs in EBPR varies and is critically assessed, in light of their calculated amplicon abundances, to indicate which of these are important in full-scale systems. Bacteria from the genus Tetrasphaera were the most abundant of the PAOs. The " Candidatus Accumulibacter" PAOs were in much lower abundance and appear to be biased by the amplicon-based method applied. The genera Dechloromonas, Microlunatus , and Tessaracoccus were identified as abundant putative PAO that require further research attention. Interestingly, the actinobacterial Micropruina and sbr-gs28 phylotypes were among the most abundant of the putative GAOs. Members of the genera Defluviicoccus, Propionivibrio , the family Competibacteraceae, and the spb280 group were also relatively abundant in some plants. Despite observed high abundances of GAOs (periodically exceeding 20% of the amplicon reads), P removal performance was maintained, indicating that these organisms were not

  15. Capsaicin-loaded nanolipoidal carriers for topical application: design, characterization, and in vitro/in vivo evaluation

    Directory of Open Access Journals (Sweden)

    Wang XR

    2017-05-01

    Full Text Available Xia-Rong Wang,1 Si-Qian Gao,1 Xiao-Qian Niu,1 Long-Jian Li,2 Xiao-Ying Ying,1 Zhong-Jie Hu,2 Jian-Qing Gao1,3 1Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 2Zhejiang Provincial Corps Hospital of Chinese People’s Armed Police Forces, Jiaxing, Zhejiang, 3Jiangsu Engineering Research Center for New-Type External and Transdermal Preparations, Jiangsu, People’s Republic of China Abstract: Capsaicin has been used in clinical applications for the treatment of pain disorders and inflammatory diseases. Given the strong pungency and high oil/water partition coefficient of capsaicin, capsaicin-loaded nanolipoidal carriers (NLCs were designed to increase permeation and achieve the analgesic, anti-inflammatory effect with lower skin irritation. Capsaicin-loaded NLCs were prepared and later optimized by the Box–Behnken design. The physicochemical characterizations, morphology, and encapsulation of the capsaicin-loaded NLCs were subsequently confirmed. Capsaicin-loaded NLCs and capsaicin-loaded NLCs gel exhibited sustained release and no cytotoxicity properties. Also, they could significantly enhance the penetration amount, permeation flux, and skin retention amounts of capsaicin due to the application of NLCs. To study the topical permeation mechanism of capsaicin, 3,3'-dioctadecyloxacarbocyanine perchlorate (Dio was used as a fluorescent dye. Dio-loaded NLCs and Dio-loaded NLCs gel could effectively deliver Dio up to a skin depth of 260 and 210 µm, respectively, primarily through the appendage route on the basis of version skin sections compared with Dio solution, which only delivered Dio up to 150 µm. In vivo therapeutic experiments demonstrated that capsaicin-loaded NLCs and capsaicin-loaded NLCs gel could improve the pain threshold in a dose-dependent manner and inhibit inflammation, primarily by reducing the prostaglandin E2 levels in the tissue compared with capsaicin cream and capsaicin solution

  16. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. XINFENG GAO. Articles written in Journal of Genetics. Volume 96 Issue 2 June 2017 pp 341-351 RESEARCH ARTICLE. Molecular characterization, expression profile of the FSHR gene and its association with egg production traits in muscovy duck · JIGUO XU XINFENG GAO XING LI ...

  17. Army Corps of Engineers: Additional Steps Needed for Review and Revision of Water Control Manuals

    Science.gov (United States)

    2016-07-01

    Techniques, GAO-14-741 (Washington, D.C.: Sept. 12, 2014). The Department of Defense agreed with our recommendation to evaluate the pros and cons of...Visa, check, or money order. Call for additional information. Connect with GAO on Facebook, Flickr, Twitter, and YouTube . Subscribe to our RSS

  18. More DoD Oversight Needed for Purchases Made Through the Department of Energy

    Science.gov (United States)

    2010-12-03

    obligations or to liquidate prior valid obligations. However, expired funds are not available for new obligations nor can they be used for new requirements...Oversight Would Enable The Department of Homeland Security To Address Risks,” September 2006 GAO Report No. GAO-05-456, “Interagency Contracting Franchise

  19. Utilization of BIA-Derived Bone Mineral Estimates Exerts Minimal Impact on Body Fat Estimates via Multicompartment Models in Physically Active Adults.

    Science.gov (United States)

    Nickerson, Brett S; Tinsley, Grant M

    2018-03-21

    The purpose of this study was to compare body fat estimates and fat-free mass (FFM) characteristics produced by multicompartment models when utilizing either dual energy X-ray absorptiometry (DXA) or single-frequency bioelectrical impedance analysis (SF-BIA) for bone mineral content (BMC) in a sample of physically active adults. Body fat percentage (BF%) was estimated with 5-compartment (5C), 4-compartment (4C), 3-compartment (3C), and 2-compartment (2C) models, and DXA. The 5C-Wang with DXA for BMC (i.e., 5C-Wang DXA ) was the criterion. 5C-Wang using SF-BIA for BMC (i.e., 5C-Wang BIA ), 4C-Wang DXA (DXA for BMC), 4C-Wang BIA (BIA for BMC), and 3C-Siri all produced values similar to 5C-Wang DXA (r > 0.99; total error [TE] FFM characteristics (i.e., FFM density, water/FFM, mineral/FFM, and protein/FFM) for 5C-Wang DXA and 5C-Wang BIA were each compared with the "reference body" cadavers of Brozek et al. 5C-Wang BIA FFM density differed significantly from the "reference body" in women (1.103 ± 0.007 g/cm 3 ; p FFM and mineral/FFM were significantly lower in men and women when comparing 5C-Wang DXA and 5C-Wang BIA with the "reference body," whereas protein/FFM was significantly higher (all p ≤ 0.001). 3C-Lohman BIA and 3C-Lohman DXA produced error similar to 2C models and DXA and are therefore not recommended multicompartment models. Although more advanced multicompartment models (e.g., 4C-Wang and 5C-Wang) can utilize BIA-derived BMC with minimal impact on body fat estimates, the increased accuracy of these models over 3C-Siri is minimal. Copyright © 2018 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

  20. Jänkid, minge põrgu! / Toomas Alatalu

    Index Scriptorium Estoniae

    Alatalu, Toomas, 1942-

    2009-01-01

    Ameerika riikide organisatsiooni (OEA) välisministrid kogunesid EL Salvadori pealinna, et osaleda Ladina-Ameerika uue vasakpoolse presidendi Mauricio Funesi ametisseastumise tseremoonial ning arutada Kuuba tagasivõtmist organisatsiooni

  1. Sexual Assault: Better Resource Management Needed to Improve Prevention and Response in the Army National Guard and Army Reserve

    Science.gov (United States)

    2017-02-01

    depression , and homelessness. Page 34 GAO-17-217 Sexual Assault in Army Reserve Components In our survey of full-time SARCs and VAs in the...or money order. Call for additional information. Connect with GAO on Facebook, Flickr, LinkedIn, Twitter, and YouTube . Subscribe to our RSS Feeds or

  2. Health Reports.

    Science.gov (United States)

    1992-09-01

    Futui’e Structure of Veterans’ Health Program (Aug. 11, 1992, GAO/T-HRD-92-53). Recombinant Bovine Growth Hormone: FDA Approval Should be Withheld Until...the Mastitis Issue Is Resolved (Aug. 6, 1992, GAO/PEMD-92-26). VA Health Care: Inadequate Controls Over Scarce Medical Specialist Contracts (Aug. 5

  3. Military Personnel: Oversight Framework and Evaluations Needed for DOD and the Coast Guard to Help Increase the Number of Female Officer Applicants

    Science.gov (United States)

    2015-11-01

    skills—such as physicians, dentists, nurses , lawyers, and Page 8 GAO-16-55 Women in the Officer Corps chaplains—who do not in all cases...Connect with GAO on Facebook, Flickr, Twitter, and YouTube . Subscribe to our RSS Feeds or E-mail Updates. Listen to our Podcasts and read The

  4. Strong Internal Controls at Service Delivery Level Will Help Prevent CETA-Type Fraud and Abuse in Job Training Partnership Act Programs. Report to Senator Sam Nunn, Ranking Minority Member, Permanent Subcommittee on Investigations, Senate Committee on Governmental Affairs.

    Science.gov (United States)

    General Accounting Office, Washington, DC.

    The Government Accounting Office (GAO) conducted an examination of patterns and causes of fraud in Comprehensive Employment and Training Act (CETA) programs to determine how implementation of Job Training Partnership Act (JTPA) programs might be made less vulnerable to exploitation. GAO's investigation found that fraud and abuse in CETA programs…

  5. Warfighter Support: Army Has Taken Steps to Improve Reset Process, but More Complete Reporting of Equipment and Future Cost Is Needed

    Science.gov (United States)

    2012-05-01

    asphalt spreaders ), other semi-trucks and trailers, palletized loading systems, and heavy equipment transports. As table 3 shows, the actual reset...Copies of GAO Reports and Testimony Order by Phone Connect with GAO To Report Fraud, Waste, and Abuse in Federal Programs Congressional Relations Public Affairs Please Print on Recycled Paper.

  6. Procurement: National Institute of Education's Procurement Practices. Report to the Chairman, Subcommittee on Intergovernmental Relations and Human Resources, Committee on Government Operations, House of Representatives.

    Science.gov (United States)

    General Accounting Office, Washington, DC. Div. of Human Resources.

    This document comprises the General Accounting Office's (GAO) report to the House Subcommittee on Intergovernmental Relations concerning the GAO's review of the contract awarding process of the National Institute of Education (NIE) for fiscal year 1983. The review focused on 39 of NIE's 52 newly negotiated procurement contracts; a sample of…

  7. Report of the Comptroller General of the United States. Comments on selected aspects of the Administration's proposal for government assistance to private uranium enrichment groups

    International Nuclear Information System (INIS)

    1976-01-01

    This report presents GAO's views on matters raised by the Vice Chairman, Joint Committee on Atomic Energy, related to the private ownership of uranium enrichment and reemphasizes GAO's belief that the Government should add on to one of its existing enrichment plants to provide the next increment of enrichment capacity

  8. Mortal Ancestors, Immortal Images: Zhang Dai’s Biographical Portraits

    Directory of Open Access Journals (Sweden)

    Duncan M. Campbell

    2012-11-01

    Full Text Available Towards the end of his long life, the prolific late-Ming historian and essayist Zhang Dai 張岱 (1597-?1684 completed a book that he had been working on for many years. Entitled Portraits of the Eminent and Worthy Immortals of Zhejiang During the Ming Dynasty (You Ming yuyue san bu xiu tuzan 有明於越三不朽名賢圖贊 the book included the short biographies (with poetic panegyrics and portraits of 109 men and women of Zhang Dai’s hometown of Shaoxing, one of the epicentres of China’s élite cultural life. The book was organised according to the “Three Immortalities of Life”: moral force, meritorious service, and wise words. Zhang also included a number of his own friends and family members in this collection. This paper discusses aspects the relationship between text and image in this late-imperial Chinese work, both in the context of Zhang Dai’s practice as a biographer who had a strong visual sense and in regard to his particular historical plight as someone who had survived the collapse of one dynasty and who had lived on under its successor regime.

  9. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 4. CuO/TiO2 nanocrystals grown on graphene as visible-light responsive photocatalytic hybrid materials. Yuan Fang Rijing Wang Guohua Jiang He Jin Yin Wang Xinke Sun Sheng Wang Tao Wang. Volume 35 Issue 4 August 2012 pp 495-499 ...

  10. [History of hot spring bath treatment in China].

    Science.gov (United States)

    Hao, Wanpeng; Wang, Xiaojun; Xiang, Yinghong; Gu Li, A Man; Li, Ming; Zhang, Xin

    2011-07-01

    As early as the 7th century B.C. (Western Zhou Dynasty), there is a recording as 'spring which contains sulfur could treat disease' on the Wentang Stele written by WANG Bao. Wenquan Fu written by ZHANG Heng in the Easten Han Dynasty also mentioned hot spring bath treatment. The distribution of hot springs in China has been summarized by LI Daoyuan in the Northern Wei Dynasty in his Shuijingzhu which recorded hot springs in 41 places and interpreted the definition of hot spring. Bencao Shiyi (by CHEN Cangqi, Tang Dynasty) discussed the formation of and indications for hot springs. HU Zai in the Song Dynasty pointed out distinguishing hot springs according to water quality in his book Yuyin Conghua. TANG Shenwei in the Song Dynasty noted in Jingshi Zhenglei Beiji Bencao that hot spring bath treatment should be combined with diet. Shiwu Bencao (Ming Dynasty) classified hot springs into sulfur springs, arsenicum springs, cinnabar springs, aluminite springs, etc. and pointed out their individual indications. Geologists did not start the work on distribution and water quality analysis of hot springs until the first half of the 20th century. There are 972 hot springs in Wenquan Jiyao (written by geologist ZHANG Hongzhao and published in 1956). In July 1982, the First National Geothermal Conference was held and it reported that there were more than 2600 hot springs in China. Since the second half of the 20th century, hot spring sanatoriums and rehabilitation centers have been established, which promoted the development of hot spring bath treatment.

  11. School Lunch Program: Role and Impacts of Private Food Service Companies. United States General Accounting Office Report to Congressional Committees.

    Science.gov (United States)

    General Accounting Office, Washington, DC. Resources, Community, and Economic Development Div.

    In the Healthy Meals for Healthy Americans Act of 1994, Congress directed the Government Accounting Office (GAO) to examine the use of private food establishments and caterers by schools participating in federal programs for school meals. In conducting its review, the GAO relied primarily on questionnaires returned by food authorities that had…

  12. 77 FR 15298 - Rule Concerning Disclosures Regarding Energy Consumption and Water Use of Certain Home Appliances...

    Science.gov (United States)

    2012-03-15

    ... amendments would require retail Web sites to post the full EnergyGuide or Lighting Facts label online.\\29... many showroom products do not have EnergyGuide labels attached. Specifically, GAO visits to 30 stores...\\ Following the GAO report, FTC staff conducted its own examination of more than 8,500 appliances in 89 retail...

  13. Homeless Mentally Ill: Problems and Options in Estimating Numbers and Trends. Report to the Chairman, Committee on Labor and Human Resources, U.S. Senate.

    Science.gov (United States)

    General Accounting Office, Washington, DC. Program Evaluation and Methodology Div.

    In response to a request by the United States Senate Committee on Labor and Human Resources, the General Accounting Office (GAO) examined the methodological soundness of current population estimates of the number of homeless chronically mentally ill persons, and proposed several options for estimating the size of this population. The GAO reviewed…

  14. Student Financial Aid. High Risk Series.

    Science.gov (United States)

    General Accounting Office, Washington, DC.

    This report discusses the continuing concerns of the U.S. General Accounting Office (GAO) in regard to the Department of Education's management and oversight of postsecondary student financial aid programs, especially the Federal Family Education Loan, the Ford Direct Loan, and the Federal Pell Grant Programs. GAO commends the department for its…

  15. An Application of Technological Maturity Assessment to ROKAF T-50 Aircraft Production Program

    National Research Council Canada - National Science Library

    Maeng, Honjae

    2005-01-01

    .... Finally the US GAO methodology assesses the production readiness of a program by examining the status of Statistical Process Quality Control (SPQC) procedures. This thesis also presents to the ROKAF decision maker an independent knowledge-based estimation of the ROKAF T-50 program by applying the US GAO methodology to the T-50 program.

  16. VA Health Care: Processes to Evaluate, Implement, and Monitor Organizational Structure Changes Needed

    Science.gov (United States)

    2016-09-01

    their families , such as medallions and markers for headstones that signify veterans’ service. Page 3 GAO-16-803 VHA Organizational ... Research Oversight, and Chief Nursing Page 8 GAO-16-803 VHA Organizational Structure Officer. Also, the Chief Financial Officer and...VA HEALTH CARE Processes to Evaluate, Implement, and Monitor Organizational Structure Changes Needed Report to

  17. DMPD: Endogenous ligands of Toll-like receptors. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 15178705 Endogenous ligands of Toll-like receptors. Tsan MF, Gao B. J Leukoc Biol. ...2004 Sep;76(3):514-9. Epub 2004 Jun 3. (.png) (.svg) (.html) (.csml) Show Endogenous ligands of Toll-like re...ceptors. PubmedID 15178705 Title Endogenous ligands of Toll-like receptors. Authors Tsan MF, Gao B. Publicat

  18. DOD Business Systems Modernization: Progress Continues to Be Made in Establishing Corporate Management Controls, but Further Steps are Needed

    Science.gov (United States)

    2007-05-01

    Officer BEA business enterprise architecture BEP business enterprise priority BTA Business Transformation Agency CIO chief information...Board IT information technology ITIM Information Technology Investment Management framework NCES Net-Centric Enterprise Services OMB...18GAO, Information Technology Investment Management: A Framework for Assessing and Improving Process Maturity, GAO-04-394G (Washington, D.C.: March 2004

  19. Contracting Data Analysis: Assessment of Government-Wide Trends

    Science.gov (United States)

    2017-03-01

    CONTRACTING DATA ANALYSIS Assessment of Government -wide Trends Report to Congressional Addressees March 2017...Office Highlights of GAO-17-244SP, a report to congressional addressees March 2017 CONTRACTING DATA ANALYSIS Assessment of Government -wide...Trends What GAO Found GAO’s analysis of government -wide contracting data found that while defense obligations to buy products and services

  20. DOD Service Acquisition: Improved Use of Available Data Needed to Better Manage and Forecast Service Contract Requirements

    Science.gov (United States)

    2016-02-01

    Requirements Report to Congressional Committees February 2016 GAO-16-119 United States Government Accountability Office United States...Government Accountability Office Highlights of GAO-16-119, a report to congressional committees February 2016 DOD SERVICE ACQUISITION Improved...attention on government operations that it identifies as high risk due to their greater vulnerabilities to fraud , waste, abuse, and mismanagement or

  1. A Theoretical Manpower Optimization Model for the Air Force Installation Contracting Agency (AFICA)

    Science.gov (United States)

    2017-12-01

    Government Accountability Office (GAO). (2011). Opportunities to reduce potential duplication in government programs, save tax dollars, and enhance revenue... Accounting Code FAR Federal Acquisition Regulation FPDS-NG Federal Procurement Data System-Next Generation FSS Federal Supply Schedule FSSI Federal...Strategic Sourcing Initiative FY Fiscal Year GAO Government Accountability Office GPC Government Purchase Card GPO Group Purchasing Organization GSA

  2. VA Health Care: Improved Monitoring Needed for Effective Oversight of Care for Women Veterans

    Science.gov (United States)

    2016-12-01

    Congressional Requesters December 2016 GAO-17-52 United States Government Accountability Office United States Government Accountability Office...VHA officials said not all facilities require onsite gynecologists and facilities may authorize gynecological services from non-VA providers. They...including previously closed combat positions, which could contribute to the increase in the women veteran population. See GAO, Military Personnel: DOD Is

  3. Structures and self-activating photoluminescent properties of Sr3−xAxGaO4F (A=Ba, Ca) materials

    International Nuclear Information System (INIS)

    Green, Robert; Vogt, Thomas

    2012-01-01

    The synthesis, structures and photoluminescent properties of mixed oxyfluorides of the type Sr 3−x A x GaO 4 F are compared to Sr 3−x A x AlO 4 F (A=Ca, Ba) materials. In these compounds the F − and O 2− ions are ordered and located on two distinct crystallographic sites. When substituting Sr 2+ by Ba 2+ and Ca 2+ , we find in Sr 3−x A x GaO 4 F materials an ordering of the alkaline earth cations over the two crystallographic sites. The amount of Ba 2+ ions that can be substituted into Sr 3−x A x GaO 4 F is x≤1.2, which is slightly more than can be incorporated into the previously reported Al-analog Sr 3−x A x AlO 4 F (x=1.0). Conversely, the amount of Ca 2+ ions that can be substituted into Sr 3−x Ca x GaO 4 F (x=0.3) is significantly less than in Sr 3−x Ca x AlO 4 F (x=1.0). A post-synthesis reduction step causes these materials to exhibit self-activating broad band photoluminescence where the emitted colors vary with the amount of ions substituted into the host lattice. - Graphical abstract: TOC Statement The structures of the self-activating phosphors Sr 3−x A x MO 4 F (A=Ba, Ca and M=Al, Ga) can be rationalized as alternating layers of bond compression and elongation, which impact the photoluminescence. Highlights: ► Comparison of the structural changes in Sr 3−x A x AlO 4 F and Sr 3−x A x GaO 4 F (A=Ba, Ca) and its influence on the photoluminescence of these self-activating phosphors. ► Analysis of the Global Instability Index of the Sr 3−x A x AlO 4 F and Sr 3−x A x GaO 4 F (A=Ba, Ca). ► Comparison of the photoluminescence between the self-activating phosphors Sr 3−x A x AlO 4 F and Sr 3−x A x GaO 4 F (A=Ba, Ca).

  4. A Critical Assessment of the Microorganisms Proposed to be Important to Enhanced Biological Phosphorus Removal in Full-Scale Wastewater Treatment Systems

    Directory of Open Access Journals (Sweden)

    Per H. Nielsen

    2017-04-01

    Full Text Available Understanding the microbiology of phosphorus (P removal is considered essential to knowledge-based optimization of enhanced biological P removal (EBPR systems. Biological P removal is achieved in these systems by promoting the growth of organisms collectively known as the polyphosphate accumulating organisms (PAOs. Also considered important to EBPR are the glycogen accumulating organisms (GAOs, which are theorized to compete with the PAOs for resources at the expense of P removal efficiency. Numerous studies have sought to identify the PAOs and their GAOs competitors, with several candidates proposed for each over the last few decades. The current study collectively assessed the abundance and diversity of all proposed PAOs and GAOs in 18 Danish full-scale wastewater treatment plants with well-working biological nutrient removal over a period of 9 years using 16S rRNA gene amplicon sequencing. The microbial community structure in all plants was relatively stable over time. Evidence for the role of the proposed PAOs and GAOs in EBPR varies and is critically assessed, in light of their calculated amplicon abundances, to indicate which of these are important in full-scale systems. Bacteria from the genus Tetrasphaera were the most abundant of the PAOs. The “Candidatus Accumulibacter” PAOs were in much lower abundance and appear to be biased by the amplicon-based method applied. The genera Dechloromonas, Microlunatus, and Tessaracoccus were identified as abundant putative PAO that require further research attention. Interestingly, the actinobacterial Micropruina and sbr-gs28 phylotypes were among the most abundant of the putative GAOs. Members of the genera Defluviicoccus, Propionivibrio, the family Competibacteraceae, and the spb280 group were also relatively abundant in some plants. Despite observed high abundances of GAOs (periodically exceeding 20% of the amplicon reads, P removal performance was maintained, indicating that these organisms

  5. ENSO events are induced by the Global Atmosphere Oscillation

    Science.gov (United States)

    Serykh, Ilya; Byshev, Vladimir; Neiman, Victor; Romanov, Juri

    2014-05-01

    The large-scale anomalies in the planetary fields of the principal hydro-meteorological characteristics were found to appear prior the beginning and during the main phase of the El Niño - Southern Oscillation (ENSO) phenomenon in the Pacific Ocean. The anomalies were interpreted as manifestation of the interannual Global Atmosphere Oscillation (GAO) in dynamics of the modern climatic system. The key feature of the GAO baric structure is a large-scale positive anomaly in tropical area (30N-30S, 50W-170E) surrounded by negative anomaly bending its outer boundaries. Eventually, such reconstruction of the atmospheric pressure field over tropical zone as a consequence of the GAO leads to Walker circulation cell reversal which is immediately followed by the next El Niño process starting. Spatio-temporal structure of the anomalous hydro-meteorological fields developing under impact of the GAO was analyzed using the monthly-mean atmospheric pressure data at sea level (HadSLP2) and near-surface temperature (CRUTEM4) prepared by GB Met Office Hadley Centre for period of 1948-2012, also we used wind data from US NCEP/NCAR reanalysis for the same period. Due to the presence of feed-forwards and feedbacks in the climate dynamics, the large-scale anomalies of characteristics appearing after the GAO cause their back effect on the system of interaction of the ocean-atmosphere-land. This is the secondary impact which can be implemented either by direct exchange of properties between the adjacent areas (this is seen most explicitly in the Indo-Pacific Region), or owing to teleconnections between the concrete climatic subsystems in different parts of the Earth. It is apparently that the secondary, or indirect, GAO impact spreading through the system of general atmospheric circulation has a certain phase shift in different areas, which depends first on the distance from the respective climatic anomalies, in particular, from the most intensive of them, appearing in the equatorial

  6. Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy

    Directory of Open Access Journals (Sweden)

    Shan L

    2015-09-01

    Full Text Available Lingling Shan,1 Ming Liu,2 Chao Wu,1 Liang Zhao,1 Siwen Li,3 Lisheng Xu,1 Wengen Cao,1 Guizhen Gao,1 Yueqing Gu3 1Institute of Pharmaceutical Biotechnology, School of Biology and Food Engineering, Suzhou University, Suzhou, People’s Republic of China; 2Department of Biology, University of South Dakota, Vermillion, SD, USA; 3Department of Biomedical Engineering, School of Life Science and Technology, China Pharmaceutical University, Nanjing, People’s Republic of China Abstract: In response to the challenges of cancer chemotherapeutics, including poor physicochemical properties, low tumor targeting ability, and harmful side effects, we developed a new tumor-targeted multi-small molecule drug delivery platform. Using paclitaxel (PTX as a model therapeutic, we prepared two prodrugs, ie, folic acid-fluorescein-5(6-isothiocyanate-arginine-paclitaxel (FA-FITC-Arg-PTX and folic acid-5-aminofluorescein-glutamic-paclitaxel (FA-5AF-Glu-PTX, composed of folic acid (FA, target, amino acids (Arg or Glu, linker, and fluorescent dye (fluorescein in vitro or near-infrared fluorescent dye in vivo in order to better understand the mechanism of PTX prodrug targeting. In vitro and acute toxicity studies demonstrated the low toxicity of the prodrug formulations compared with the free drug. In vitro and in vivo studies indicated that folate receptor-mediated uptake of PTX-conjugated multi-small molecule carriers induced high antitumor activity. Notably, compared with free PTX and with PTX-loaded macromolecular carriers from our previous study, this multi-small molecule-conjugated strategy improved the water solubility, loading rate, targeting ability, antitumor activity, and toxicity profile of PTX. These results support the use of multi-small molecules as tumor-targeting drug delivery systems. Keywords: multi-small molecules, paclitaxel, prodrugs, targeting, tumor therapy

  7. Characterization, pharmacokinetics, and hypoglycemic effect of berberine loaded solid lipid nanoparticles

    Directory of Open Access Journals (Sweden)

    Xue M

    2013-12-01

    Full Text Available Mei Xue, Ming-xing Yang, Wei Zhang, Xiu-min Li, De-hong Gao, Zhi-min Ou, Zhi-peng Li, Su-huan Liu, Xue-jun Li, Shu-yu Yang Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, Xiamen, People’s Republic of China Abstract: The high aqueous solubility, poor permeability, and absorption of berberine (BBR result in its low plasma level after oral administration, which greatly limits its clinical application. BBR solid lipid nanoparticles (SLNs were prepared to achieve improved bioavailability and prolonged effect. Developed SLNs showed homogeneous spherical shapes, small size (76.8 nm, zeta potential (7.87 mV, encapsulation efficiency (58%, and drug loading (4.2%. The power of X-ray diffraction combined with 1H nuclear magnetic resonance spectroscopy was employed to analyze chemical functional groups and the microstructure of BBR-SLNs, and indicated that the drug was wrapped in a lipid carrier. Single dose (50 mg/kg oral pharmacokinetic studies in rats showed significant improvement (P<0.05 in the peak plasma concentration, area under the curve, and variance of mean residence time of BBR-SLNs when compared to BBR alone (P<0.05, suggesting improved bioavailability. Furthermore, oral administration of both BBR and BBR-SLNs significantly suppressed body weight gain, fasting blood glucose levels, and homeostasis assessment of insulin resistance, and ameliorated impaired glucose tolerance and insulin tolerance in db/db diabetic mice. BBR-SLNs at high dose (100 mg/kg showed more potent effects when compared to an equivalent dose of BBR. Morphologic analysis demonstrated that BBR-SLNs potentially promoted islet function and protected the islet from regeneration. In conclusion, our study demonstrates that by entrapping BBR into SLNs the absorption of BBR and its anti-diabetic action were effectively enhanced. Keywords: berberine, solid lipid nanoparticles, pharmacokinetic, hypoglycemic effect

  8. Fake "Returnee" Earns 4 Million through Fraudulent Marriages: More than Ten Women Fall for His Claims of Being a Boss and Possessing a House and Car

    Science.gov (United States)

    Chinese Education and Society, 2005

    2005-01-01

    This article discusses the case of Wang Ruiliang. Ms. Huang filed a case against Wang Jun, alleging that he had defrauded her. Ms. Huang met a man named Wang Jun in April 2002 through a certain matrimonial agency. Before they had been together for very long, Wang Jun asked to borrow money from Ms. Huang, claiming that he was having difficulties in…

  9. Call for Papers and Announcement Joint International Conference of Industrial Engineering and Engineering Management (IE&EM'2002)And International Conference on Electronic Commerce Engineering (ICECE'2002)%“2002年工业工程与工程管理国际会议(IE&EM’2002)”暨“2002年电子商务工程国际会议(IceCE’2002)”征文通知

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Metropolitan University, UK Members: (in alphabetic order) Fukuda Shuichi (Japan) Ning Ruxin (China) Qi Ershi (China) Mitchell M. Tseng (HK) G. Doumeingts (France) Richard Harrison (UK) Jim Browne (Ireland) F.-L Krause (Germany) Lei Yuanzhong (NSFC, China) Li Ming (NSFC, China) Li Peigeng (China) Liu Fei (China) Lin Zhongqin(863/automation, China) Roddy MacLeod (UK) Chris McMahon (UK) Martin Moltrecht(Germany) Sun Jiaguang (863/automation, China) Tang Xiaoqing (China) Wang Ruigang (CMES, China) Wang Yingluo(China) Wen Yuping (Tsinghua, Taiwan) Xia Guoping (China) Yan Junqi (China) Organizing Committee Chairman: Zheng Li, Tsinghua University (China) Co-Chairmen: Kai Cheng (UK) Jiang Pingyu (China) Guoquan Huang (Hong Kong) Li Congdong (China) Members: (in alphabetic order) Richard Bateman (UK) Liu Dacheng (China) Pan P.Y. (UK) Jeremy Toussaint (UK) Wu Shu(China) Yu Ming (China)Secretariat: General Secretary: Yu Ming (China) Members: Cai Linning (China) Jiang Zhibin (China) Yi Shuping (China) Zeng Haiming(China) Zhang Wei (China) Zhao Huanmai (China) Submissions Submitted papers should be in English and will be accepted in two types: regular papers limited to 8 pages, after that S|100 per additional page, but no more than 12 pages, and short papers limited to 4 pages. Papers submitted should be in MS Word or its compressed (zip) form. The format of submitted papers is: A4, 20mm margin at left side and 28mm at right side; double column, each 81mm wide with a 8mm space between columns; 18pt Times New Roman for the title; 10.5pt Times New Roman for text, author(s), affiliation(s), mailing address(es) and e-mail address(es); the space between lines is single space and the space between words is standard. On the first page, the top 50mm of both columns should be reserved for the title, author(s), affiliation(s), mailing address(es) and email address(es), which should be centered across both columns; on the second and subsequent pages, the text or illustrations should begin at the top

  10. Photodynamic antimicrobial chemotherapy for Staphylococcus aureus and multidrug-resistant bacterial burn infection in vitro and in vivo

    Directory of Open Access Journals (Sweden)

    Mai B

    2017-08-01

    Full Text Available Bingjie Mai,1,2 Yiru Gao,1,2 Min Li,1,2 Xiaobing Wang,1,2 Kun Zhang,1,2 Quanhong Liu,1,2 Chuanshan Xu,3 Pan Wang1,2 1Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry, Ministry of Education, 2National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi’an, 3School of Chinese Medicine, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China Background and objectives: Antibiotic resistance has emerged as one of the most important determinants of outcome in patients with serious infections, along with the virulence of the underlying pathogen. Photodynamic antimicrobial chemotherapy (PACT has been proposed as an alternative approach for the inactivation of bacteria. This study aims to evaluate the antibacterial effect of sinoporphyrin sodium (DVDMS-mediated PACT on Staphylococcus aureus and multidrug resistant S. aureus in vitro and in vivo.Materials and methods: Bacteria were incubated with DVDMS and exposed to treatment with light. After PACT treatment, colony-forming units were counted to estimate the bactericidal effect. Intracellular reactive oxygen-species production was detected by flow cytometry. Flow cytometry and fluorescence-microscopy detection of bacterial cell-membrane permeability. Enzyme-linked immunosorbent assays were used to determine expression of VEGF, TGFβ1, TNFα, IL6, and bFGF factors in burn infection.Results: DVDMS-PACT effectively killed bacterial proliferation. Intracellular ROS levels were enhanced obviously in the PACT-treatment group. SYTO 9 and propidium iodide staining showed a decrease in the ratio of green:red fluorescence intensity in the PACT-treatment group in comparison to the control group. Enzyme-linked immunosorbent-assay results revealed that in the healing process, the expression of bFGF, TGFβ1, and VEGF in the treatment group were higher than in the control group

  11. CXCL12 suppresses cisplatin-induced apoptosis through activation of JAK2/STAT3 signaling in human non-small-cell lung cancer cells

    Directory of Open Access Journals (Sweden)

    Wang M

    2017-06-01

    Full Text Available Meng Wang,1 Tie Lin,2 Yicun Wang,3 Song Gao,4 Zhaoyang Yang,1 Xuan Hong,1 Gongyan Chen1 1Department of Respiratory Medicine, Harbin Medical University Cancer Hospital, 2Department of Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, 3Jilin Provincial Key Laboratory on Molecular and Chemical Genetics, The Second Hospital of Jilin University, Changchun, 4Department of Clinical Oncology, Shengjing Hospital, China Medical University, Shenyang, People’s Republic of China Aims: Poor efficacy of chemotherapy drugs in non-small-cell lung cancer (NSCLC is the key reason for the failure of treatment, but the mechanism of this remains largely unknown. Stromal cell-derived factor 1-alpha (SDF-1α/CXCL12 is a small chemotactic cytokine protein that plays an important role in tumor progression. In this study, we investigated the anti-apoptotic mechanism of the CXCL12/CXCR4 axis in response to cisplatin, a commonly used chemotherapeutic drug, in human lung adenocarcinoma A549 cells.Methods: CXCL12 blocks cisplatin-induced apoptosis in A549, and the results were shown by propidium iodide/annexin V staining in vitro. The mechanism of CXCL12 stimulating phosphorylation of STAT3 through CXCR4/JAK2 was demonstrated by immunofluorescence and Western blotting. The expression of CXCL12 and p-STAT3 in clinical specimens was examined by immunohistochemistry.Results: CXCL12 significantly decreased the ratio of apoptotic cells and stimulation of phospho-signal transducer and activator of transcription (p-STAT-3 in a time-dependent manner through interaction with CXCR4. Among the signaling molecules downstream of CXCR4, the JAK2/STAT3 pathway plays a predominant role in the anti-apoptotic effect of CXCL12. Analysis of clinical specimens revealed that increased CXCL12 and p-STAT3 expression correlates with enhanced lung cancer progression.Conclusion: These data suggest that CXCR4 contributes to CXCL12-mediated anti-apoptosis by activating JAK2

  12. Role of presurgical targeted molecular therapy in renal cell carcinoma with an inferior vena cava tumor thrombus

    Directory of Open Access Journals (Sweden)

    Peng C

    2018-04-01

    Full Text Available Cheng Peng,1,* Liangyou Gu,1,* Lei Wang,2 Qingbo Huang,1 Baojun Wang,1 Gang Guo,1 Yang Fan,1 Yu Gao,1 Xin Ma,1 Xu Zhang1 1Department of Urology, State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Chinese PLA Medical Academy, Beijing, People’s Republic of China; 2Department of Urology, Chinese PLA 534 Hospital, Luoyang, People’s Republic of China *These authors contributed equally to this work Purpose: The clinical benefit of targeted molecular therapy (TMT in renal cell carcinoma (RCC with an inferior vena cava (IVC tumor thrombus remains controversial. The aim of this study was to investigate the effects of presurgical TMT on the heights and levels of IVC thrombi, and to assess its impact on surgical strategy. Patients and methods: We retrospectively reviewed data from 18 patients with RCC involving IVC tumor thrombi who were treated at our hospital with presurgical TMT followed by an IVC thrombectomy. The changes in heights and levels of the IVC thrombi were compared using computed tomography or magnetic resonance imaging. Clinicopathological factors were also evaluated to assess their association with TMT efficacy. Results: The tumor thrombus levels before TMT were stage I in 1 patient (5.6%, II in 12 patients (66.7%, III in 4 patients (22.2%, and IV in 1 patient (5.6%. After a median of two treatment cycles (range: 1–3, the thrombus height decreased measurably in 11 patients (61.1% with an average shrinkage of 17.7%. The thrombus height remained stable in five patients (27.8% and was enlarged in two (11.1%. Downstaging of the thrombus level occurred in four patients (22.2%; the surgical strategy was modified in three patients (16.7% to avoid cardiopulmonary bypass and complicated liver mobilization under robot-assisted laparoscopy. Furthermore, a higher neutrophil count tended to be associated with a worse clinical TMT-associated outcome (P=0.056. Conclusion: Our data suggest a limited influence of presurgical TMT

  13. Information Technology: Opportunities for Improving Acquisitions and Operations

    Science.gov (United States)

    2017-04-01

    1GAO, Federal Chief Information Officers : Opportunities Exist to Improve Role in Information Technology Management, GAO-11-634...approach and a collaborative relationship among agency executives (e.g., Chief Financial Officer and agency component leadership) had stopped 45...executives, including Chief Financial Officers and executives of major bureaus and component agencies for whom the technology is serving, to ensure that

  14. DOD Business Systems Modernization: Further Actions Needed to Address Challenges and Improve Accountability

    Science.gov (United States)

    2013-05-01

    to Lack Adequate Validation Page 35 GAO-13-557 DOD Business Systems Modernization provided a compliance dashboard to document BEA...campaigns, execute marketing campaigns, and measure and evaluate the performance of marketing campaigns. Order-to- Cash Accept and process customer... dashboards reflected related GAO reports. In addition, the department’s fiscal year 2014 investment management guidance issued by the Office of the

  15. Defense Infrastructure: DOD Efforts to Prevent and Mitigate Encroachment at Its Installations

    Science.gov (United States)

    2016-11-01

    installation size and projected population growth . What GAO Recommends GAO is not making recommendations in this report. DOD provided technical...Projected Population Growth at 33 Selected Installations (2015 to 2020) 32 Table 4: Summary of Benefits Reported by Readiness and Environmental...installation of interest because of the existence of or potential for future incompatible land use, and (4) projected population growth in adjacent

  16. Master investor Takes Charge

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    China’s market-oriented operation of its for- eign exchange reserves, the world’s largest,made substantial progress with the inauguration of a long- awaited investment ann on September 29.Among the company’s star-studded management team is Gao Xiqing,a former Wall Street lawyer,who is tasked with day-to-day investment decisions. Gao has been designated as gen-

  17. Defense Acquisitions: Assessments of Selected Weapon Programs

    Science.gov (United States)

    2017-03-01

    Figure 17: Examples of Knowledge Scorecards 61 Page vi GAO-17-333SP Assessments of Selected Weapon Programs...programs. Page 61 GAO-17-333SP Assessments of Selected Weapon Programs Figure 17: Examples of Knowledge Scorecards Pursuant to a...had direct access to the USD AT&L and other senior acquisition officials, and some approval authorities were delegated to lower levels. For example

  18. Casualty Assistance: DOD and the Coast Guard Need to Develop Policies and Outreach Goals and Metrics for Program Supporting Servicemembers Survivors

    Science.gov (United States)

    2016-06-01

    Government Accountability Office United States Government Accountability Office Highlights of GAO-16-569, a report to the Committee on Armed...active duty, officials told us that Military OneSource provides grief counseling, tax assistance (such as Page 9 GAO-16-569 Gold Star...Advocates assistance with filing the deceased servicemember’s final tax return), and assistance with obtaining benefits. There are also organizations

  19. DOD Major Automated Information Systems: Improvements Can Be Made in Reporting Critical Changes and Clarifying Leadership Responsibility

    Science.gov (United States)

    2016-03-01

    Leadership Responsibility Report to Congressional Committees March 2016 GAO-16-336 United States Government Accountability Office United...INFORMATION SYSTEMS Improvements Can Be Made in Reporting Critical Changes and Clarifying Leadership Responsibility Why GAO Did This Study The National...milestone decisions for MAIS programs. AT&L can delegate decision authority for MAIS programs to a component head who may further delegate the authority

  20. Grafting functional antioxidants on highly crosslinked polyethylene

    Science.gov (United States)

    Al-Malaika, S.; Riasat, S.; Lewucha, C.

    2016-05-01

    The problem of interference of antioxidants, such as hindered phenols, with peroxide-initiated crosslinking of polyethylene was addressed through the use of functional (reactive) graftable antioxidants (g-AO). Reactive derivatives of hindered phenol and hindered amine antioxidants were synthesised, characterised and used to investigate their grafting reactions in high density polyethylene; both non-crosslinked (PE) and highly peroxide-crosslinked (PEXa). Assessment of the extent of in-situ grafting of the antioxidants, their retention after exhaustive solvent extraction in PE and PEXa, and the stabilising performance of the grafted antioxidants (g-AO) in the polymer were examined and benchmarked against conventionally stabilised crosslinked & non-crosslinked polyethylene. It was shown that the functional antioxidants graft to a high extent in PEXa, and that the level of interference of the g-AOs with the polymer crosslinking process was minimal compared to that of conventional antioxidants which bear the same antioxidant function. The much higher level of retention of the g-AOs in PEXa after exhaustive solvent extraction, compared to that of the corresponding conventional antioxidants, accounts for their superior long-term thermal stabilising performance under severe extractive conditions.

  1. Recent Trends in the Adequacy of Nuclear Plant Decommissioning Funding

    International Nuclear Information System (INIS)

    Williams, D. G.

    2002-01-01

    Concerned about the potential cost and sufficiency of funds to decommission the nation's nuclear power plants, the Congress asked the U.S. General Accounting Office (GAO) to assess the adequacy, as of December 31, 1997, of electric utilities'; funds to eventually decommission their plants. GAO's report (GAO/RCED-99-75) on this issue addressed three alternative assumption scenarios--baseline (most likely), optimistic, and pessimistic; and was issued in May 1999. This paper updates GAO's baseline assessment of fund adequacy in 1997, and extends the analysis through 2000. In 2000, we estimate that the present value cost to decommission the nation's nuclear plants is about $35 billion; utility fund balances are about $29 billion. Both our two measures of funding adequacy for utilities are on average not only much above ideal levels, but also overall have greatly improved since 1997. However, certain utilities still show less than ideal fund balances and annual contributions. We suggest that the range of these results among the individual utilities is a more important policy measure to assess the adequacy of decommissioning funding than is the funding adequacy for the industry as a whole

  2. Two new genera and three new species of Epipaschiinae Meyrick from China (Lepidoptera, Pyralidae

    Directory of Open Access Journals (Sweden)

    Mingqiang Wang

    2017-12-01

    Full Text Available Two new genera of Epipaschiinae are described. The genus Arcanusa Wang, Chen & Wu, gen. n. is established for Ar. apexiarcanusa Wang, Chen & Wu, sp. n. and Ar. sinuosa (Moore, 1888, comb. n., described in Scopocera Moore, 1888 (junior synonym of Stericta Lederer, 1863. The female genitalia of Ar. sinuosa (Moore, 1888, comb. n. are described for the first time. Androconia Wang, Chen & Wu, gen. n. is erected, including two new species, An. rallusa Wang, Chen & Wu, sp. n. and An. morulusa Wang, Chen & Wu, sp. n. Illustrations of all adults and their genitalia, and a key to the two new genera are provided.

  3. Stability of embossed PEI-(PSS-PDADMAC) 20 multilayer films versus storage time and versus a change in ionic strength

    Science.gov (United States)

    Ladhari, Nadia; Hemmerlé, Joseph; Haikel, Youssef; Voegel, Jean-Claude; Schaaf, Pierre; Ball, Vincent

    2008-12-01

    The use of microstructured films increased markedly in many areas of science and technology, notably in the design of microfluidic channels and in the design of parallel biosensing arrays. The concept of imprinting polyelectrolyte multilayer films (PEMs) has been introduced recently [C. Gao, B. Wang, J. Feng, J. Shen, Macromolecules 37 (2004) 8836]. These irreversibly imprinted films, obtained by plastic deformation, have to keep their size and shape after contact with fluids having physicochemical properties comparable to those of biological fluids in order to be used as microfluidic channels. We demonstrate herein that PEI-(PSS-PDADMAC) 20 PEMs built-up by the spray deposition from NaCl 1 M solutions and subsequently imprinted with polydimethylsiloxane stamps keep their morphology over time (up to 9 months) when stored in the dry state. In addition the depth of the imprinted channels does not change over this time duration. When the embossed films are immersed in NaCl 0.15 M solutions, mimicking biological fluids, the depth of the imprinted channels also does not significantly change. But, when the imprinted films prepared in the presence of 1 M NaCl are subsequently dipped in a 4 M NaCl solution, partial film loss and subsequent disappearance of the imprinted channels are observed. An explanation for these findings is furnished by means of FTIR spectroscopy in the attenuated total reflection mode (ATR-FTIR). These observations should offer large opportunities for the use of the imprinted multilayer films as microfluidic channels.

  4. The Role of SIRT1 In Breast Cancer Stem Cells

    Science.gov (United States)

    2016-09-01

    2009;9:123-8. 56. Ma W, Xiao GG, Mao J, Lu Y, Song B, Wang L, Fan S, Fan P, Hou Z, Li J, Yu X, 20 Wang B, Wang H, Wang H, Xu F, Li Y, Liu Q, Li L...Int J Biol Sci. 2010;6:599-612. 63. Zhang Y, Zhang M, Dong H, Yong S, Li X, Olashaw N, Kruk PA, Cheng JQ, Bai W, Chen J, Nicosia SV, Zhang X

  5. Bid Protests on DoD Source Selections

    Science.gov (United States)

    2017-06-13

    values, Government Accountability Office 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF 18. NUMBER a. REPORT b. ABSTRACT c. THIS PAGE ABSTRACT OF...Logistics (AT&L) closely monitors the Government Accountability Office (GAO) Bid Protest statistics for trends. These statistics combined with our trend...protests, cost claims, and requests for reconsideration. This report discusses protests only. The GAO reports case types by docket numbers (B-#) where

  6. Quantitative Risks

    Science.gov (United States)

    2015-02-24

    design failure modes and effects analysis (DFMEA), (b) Fault Tree Analysis ( FTA ) for all essential functions listed in the Failure Definition and...subsystem reliability date from Accomplishment 3, completed (a) updated DFMEA, (b) updated FTA , (c) updated reliability and maintainability estimates, (d...www.gao.gov/assets/660/658615.pdf [4] Karen Richey. Update to GAO’s Cost Estimating Assessment Guide and Scheduling Guide (draft). GAO. Mar 2013

  7. Patriot Modernization: Oversight Mechanism Needed to Track Progress and Provide Accountability

    Science.gov (United States)

    2016-08-01

    2013 and 2021 for Patriot Ongoing Upgrades to Address Obsolescence Issues 19 Figure 5: Fielding Schedule and Breakdown of Total $827.6 Million in...upgrade efforts. To conduct this review, GAO examined Army and program documents including test plans and schedules . GAO also interviewed Department...are intended to improve the system’s performance, reliability, and communications as well as address obsolescence and sustainment issues. The figure

  8. Defense Weather Satellites: DOD Faces Acquisition Challenges for Addressing Capability Needs

    Science.gov (United States)

    2016-07-07

    and compare the operational effectiveness and life cycle costs of potential solutions. This testimony is based on a report GAO issued in March...Technology, House of Representatives For Release on Delivery Expected at 10 a.m. ET Thursday, July 7, 2016 GAO-16-769T United States...Environment, Committee on Science, Space, and Technology, House of Representatives July 2016 DEFENSE WEATHER SATELLITES DOD Faces Acquisition

  9. Developing a Comprehensive Approach Could Help DOD Better Manage National Security Risks in the Supply Chain

    Science.gov (United States)

    2016-02-01

    supply chains for rare earths.20 According to Industrial Analysis Center officials, only 10 percent of surveys sent to prime contractors for 79...the Supply Chain Report to Congressional Committees February 2016 GAO-16-161 United States Government Accountability Office United...Developing a Comprehensive Approach Could Help DOD Better Manage National Security Risks in the Supply Chain Why GAO Did This Study DOD depends on

  10. Counterterrorism: DOD Should Enhance Management of and Reporting on Its Global Train and Equip Program

    Science.gov (United States)

    2016-04-01

    this work may contain copyrighted images or other material , permission from the copyright holder may be necessary if you wish to reproduce this... material separately. Page 1 GAO-16-368 Counterterrorism 441 G St. N.W. Washington, DC 20548 April 18, 2016 Congressional Committees...The fiscal year 2015 National Defense Authorization Act (NDAA) included a provision for GAO to conduct biennial audits of programs conducted pursuant

  11. The Port Security Grant Program: Good Enough, or Can it be Made Better

    Science.gov (United States)

    2016-06-01

    Statement of William O. Jenkins , Jr., Director Homeland Security and Justice, GAO 12-526T (Washington, DC, 2012) 4- 11, http://www.gao.gov/assets/590...127 de Rugy, “What Does Homeland Security Spending Buy?,” 13. 128 Yacov Haimes, Joost Santos, Kenneth Crowther, Matthew Henry ...Preparedness Grants and Assessing National Capabilities: Continuing Challenges Impede FEMA’s Progress, Statement of William O. Jenkins , Jr

  12. Government Support for Synthetic Pipeline Gas Uncertain and Needs Attention.

    Science.gov (United States)

    1982-05-14

    coal gas. Tear Sheetii RECOMMENDATIONS GAO recommends that the Secretary of Energy - --establish a plan to guide future support of high-Btu coal...recognizes that there are basic dif- ferences expected from large and small scale research projects, GAO believes that the report recognizes these...transportation, including the pipeline system. In its price-setting, or ratemaking function, it represents the interests of gas customers, sometimes

  13. Using datamining approaches to selectacupoints in acupuncture ...

    African Journals Online (AJOL)

    Using datamining approaches to selectacupoints in acupuncture and Moxibustion for knee osteoarthritis. Changyan Liu, Youxin Su, Jian He, Yanan Li, Shaoqing Chen, Yingjie Zhang, Ziyi Zhang, Meili Lu, Zhen He, Wenting Wang, Yiru Wang, Lu Sheng, Zhengxuan Zhan, Xu Wang, Naixi Zheng ...

  14. Local structure of gallate proton conductors

    International Nuclear Information System (INIS)

    Giannici, F; Messana, D; Martorana, A; Longo, A; Sciortino, L

    2009-01-01

    Lanthanum barium gallate proton conductors are based on disconnected GaO 4 groups. The insertion of hydroxyls in the LaBaGaO 4 network proceeds through self-doping with Ba 2+ , consequent O 2- vacancy formation to fulfill charge neutrality. With a structural investigation on self-doped LaBaGaO 4 oxides using synchrotron XRD and EXAFS on the Ga K-edge, we find that: (a) the GaO 4 tetrahedra retain their size throughout the whole series; (b) the GaO 4 tetrahedra rotate as rigid bodies on hydration, leading to the formation of a network of shorter O-O configurations that are stabilized by hydrogen bonds; (c) contraction of the lattice occurs along the a unit cell axis, as a consequence of an overall structural rearrangement of the hydrated solid.

  15. Local structure of gallate proton conductors

    Science.gov (United States)

    Giannici, F.; Messana, D.; Longo, A.; Sciortino, L.; Martorana, A.

    2009-11-01

    Lanthanum barium gallate proton conductors are based on disconnected GaO4 groups. The insertion of hydroxyls in the LaBaGaO4 network proceeds through self-doping with Ba2+, consequent O2- vacancy formation to fulfill charge neutrality. With a structural investigation on self-doped LaBaGaO4 oxides using synchrotron XRD and EXAFS on the Ga K-edge, we find that: (a) the GaO4 tetrahedra retain their size throughout the whole series; (b) the GaO4 tetrahedra rotate as rigid bodies on hydration, leading to the formation of a network of shorter O-O configurations that are stabilized by hydrogen bonds; (c) contraction of the lattice occurs along the a unit cell axis, as a consequence of an overall structural rearrangement of the hydrated solid.

  16. Unsteady Model for Transverse Fluid Elastic Instability of Heat Exchange Tube Bundle

    Directory of Open Access Journals (Sweden)

    Jun Liu

    2014-01-01

    Full Text Available From the viewpoint of practical application, based on the unsteady analytical model for transverse fluid elastic instability of tube array proposed by Yetisir and the linear attenuation function introduced by Li Ming, a new explicit model based on nonsteady state “streamtube” hypothesis is proposed and solved using complex number method. In the model, numerical integral is avoided and inappropriate aspects in Li Ming model are modified. Using the model, the fluid elastic instability analysis of a single flexible tube is made. The stability graphs for four typical types of tube array are plotted and contrasted with experimental results. It is found that the current explicit model is effective in the analysis of transverse fluid elastic instability of tube bundle.

  17. [Brief introduction of geo-authentic herbs].

    Science.gov (United States)

    Liang, Fei; Li, Jian; Zhang, Wei; Zhang, Rui-Xian

    2013-05-01

    The science of geo-authentic herbs is a characteristic discipline of traditional Chinese medicine established during thousands of years of clinical practices. It has a long history under the guidance of profound theories of traditional Chinese medicine. The words of "geo-authentic product" were derived from an administrative division unit in the ancient times, which layed stress on the good quality of products in particular regions. In ancient records of traditional Chinese medicine, the words of "geo-authentic product" were first found in Concise Herbal Foundation Compilation of the Ming dynasty, and the words of "geo-authentic herbs" were first discovered in Peony Pavilion of the late Ming dynasty. After all, clinical effect is the fundamental evaluation standard of geo-authentic herbs.

  18. The Body As Cogito: A Certain Contemporary Film In The Light of Merleau-Ponty

    Directory of Open Access Journals (Sweden)

    Julio Bezerra

    2014-04-01

    Full Text Available Contemporary film is displaying a kind of "transnational new wave" that seems unique since the mid-60s. Filmmakers as diverse as Tsai Ming-Liang, Karim Aïnouz, and Apichatpong Weerasethakul, show a similar sensitivity towards the values of the world and of the cinema. What brings the work of these directors together is the taste for a realism more focused on the phenomenon of experience, on issues of skin and surface, and a different look at the body. Our hypothesis is that the phenomenology of Merleau-Ponty provides us with valuable tools to broaden the debate. The discussion will be carried out by an analysis of the work of Tsai Ming-Liang, Apichatpong Weerasethakul and Karim Aïnouz.

  19. Growth, yield and quality responses to gibberellic acid (GA3)of Wax ...

    African Journals Online (AJOL)

    Administrator

    2011-09-26

    Sep 26, 2011 ... acids (GAs) have been shown to increase fruit set and growth (Zabadal and ..... 350. El-Sese AMA (2005). Effect of gibberellic acid 3 (GAs) on yield and fruit ... Wang CF, You YF, Chen XS, Wang-Lu J, Wang J (2004). Adjusting.

  20. 论王安石“善恶由习”人性论的理论渊源及其内容%On the Theoretical Origins and Contents of Wang Anshi's Theory of Human Nature on the Good and Evil Emerged from the Habit and Custom

    Institute of Scientific and Technical Information of China (English)

    欧阳辉纯

    2012-01-01

    Traditional ethical thinking theory of human nature provided theoretical basis for Wang Anshi' s. The theory of human nature in traditional ethical thinking history is mainly as follows, that is, the theory advanced by Mencius that human nature is good from birth, the theory put forward by Xunzi that human nature is evil from birth, the theory put forward by Sh- ishuo that human nature is both good and evil from birth, the Sanpin theory advanced by Dong Zhongshu, the theory put for-ward by Yangxiong that human nature is mixed goodness and evilness, and the Sanpin theory of disposition advanced by Hanyu. Wang Anshi's theory of human nature on the good and evil emerged from the habit and custom originates from critical-ly drawing on the results of previous theory of human nature. It is to the traditional theory of human nature to inject new mean-ing, to open up new realm, and thus it has an important position in traditional ethical thinking history in China.%传统人性论是王安石人性论形成的理论来源。传统伦理思想史上的人性论主要有孟子的性善论、告子的性无善无恶论、苟子的性恶论、世硕的性有善有恶论、董仲舒的性三品论、扬雄的性善恶混论和韩愈的性情三品说。王安石批判地吸收了前人的人性论成果,形成了他的“善恶由习”的人性论。他的人性论给传统人性论注入了新的内涵,开拓了新的境界,因而在中国伦理思想史上具有重要的地位。

  1. F-35 Joint Strike Fighter: Preliminary Observations on Program Progress

    Science.gov (United States)

    2016-03-23

    current fighter aircraft. The cost of extending the lives of current fighter aircraft and acquiring other major weapon systems, while continuing to... Norway . Ongoing Manufacturing and Reliability Progress Continue Page 12 GAO-16-489T rework, and repair costs have remained steady over...Program Progress Why GAO Did This Study With estimated acquisition costs of nearly $400 billion, the F-35 Joint Strike Fighter—also known as the

  2. Foreign Affairs: Specific Action Plan Needed to Improve Response to Parental Child Abductions

    Science.gov (United States)

    2000-03-01

    the child or prejudice to interested parties; (3) secure the voluntary return of the child or to bring about an amicable resolution of the issues, and...FOREIGN AFFAIRS Specific Action Plan Needed to Improve Response to Parental Child Abductions DISTRIBUTION STATEMENT A Approved for Public Release...International Parental Child Abduction 17 Page 1 GAO/NSIAD-00-10 Parental Child Abduction Page 2 GAO/NSIAD-00-10 Parental Child Abduction GAP

  3. Evaluation of Contracting and Production Activities at: The Defense Logistics Agency’s Defense Supply Centers. Volume 3. Defense Personnel Support Center Review.

    Science.gov (United States)

    1984-03-01

    with GAO; GAO sustained only 1. The Maybank Amendment also complicates both the bidding and award process. Normally, the DoD Appropriation Act...precludes DoD from paying a price differential on contracts awarded for labor surplus area (LSA) set-asides. This restriction, known as the Maybank Amendment...personnel believe that the frequency of bid protests has increased as a consequence of the bidding complica- tions introduced by the Maybank revision

  4. Computer Security: Virus Highlights Need for Improved Internet Management

    Science.gov (United States)

    1989-06-01

    Kingdom. Page 47 GAO/IMTEC-89-57 Internet Computer Virus Appendix III Major Contributors to This Report Information Management and Technology ...resources; disrupts the intended use of the Internet ; or wastes resources, destroys the integrity of computer -based information , or compromises users...and information from the other party in order to assist in preparation for trial. Page 32 GAO/IMTEC-89-57 Internet Computer Virus Chapter 3 Factors

  5. VA Disability Benefits: Additional Planning Would Enhance Efforts to Improve the Timeliness of Appeals Decisions

    Science.gov (United States)

    2017-03-01

    must manually review and correct most incoming cases due to issues with labeling, mismatched dates, and missing files. Via an internal study, VA...individuals acclimate to their jobs —and factored this into the modeling assumptions used to project the number of Board staff needed. More...Needed to Promote Increased User Satisfaction . GAO-15-582 (Washington, D.C.: September 1, 2015). Page 29 GAO-17-234 VA Disability

  6. DOD Financial Management: Continued Actions Needed to Address Congressional Committee Panel Recommendations

    Science.gov (United States)

    2015-09-01

    which was intended to fundamentally transform DOD’s financial management operations and achieve clean financial 12GAO-15-290. 13GAO-15-290. 14Pub...Actions to Implement the Panel on Defense Financial Management and Auditability Reform Recommendations valuations for these assets. For example, DOD’s...governance, the department is managing its business systems, including ERP systems, as portfolios of investments . The goal is to aggregate data from

  7. Study on the chemical composition features of Longquan celadon excavated from the Chuzhou site of Huai'an City in Jiangsu Province by EDXRF

    Science.gov (United States)

    Li, Li; Feng, Song-Lin; Feng, Xiang-Qian; Xu, Qing; Yan, Ling-Tong; Ma, Bo; Huo, Hua

    2011-07-01

    A mass of Longquan celadon shards were excavated from the Chuzhou site of Huai'an City in Jiangsu Province, China. These celadon shards were fired during the period of the Late Yuan Dynasty to the Tianshun era of the Ming Dynasty, as identified by archaeologists at Nanjing Museum. In order to research the chemical composition features of this ancient celadon porcelain, energy dispersive X-ray fluorescence (EDXRF) for non-destructive analysis was used to determine the chemical composition of the porcelain body and glaze in these shards. The results indicate that Ti and Fe in the body of Longquan celadon are characteristic elements which can distinguish porcelain produced during the Late Yuan Dynasty from those produced in the Ming Dynasties. The results of the principal component analysis (PCA) show that different body and glaze raw materials were used for the production of porcelain in different periods and the raw materials of the body and glaze are also different for various vessel shapes. The chemical compositions in the porcelain body of civilian ware are slightly different. The imperial and civilian Longquan celadon porcelains produced during the Hongwu era to the Tianshun era of the Ming Dynasty are distinguishable by the MnO, Fe2O3, Rb2O and SrO content in their porcelain glaze.

  8. Browse Title Index

    African Journals Online (AJOL)

    Items 201 - 250 of 449 ... Vol 65 (2012), Nano-Fe3O4/O2: Green, Magnetic and Reusable Catalytic System for the ... Vol 70 (2017), Novel silver-doped NiTiO3: auto-combustion synthesis, ... K Wang, H Wang, R Wang, J Key, V Linkov, S Ji.

  9. Comments on H.R. 2480

    International Nuclear Information System (INIS)

    Rezendes, V.S.

    1990-10-01

    GAO testified on H.R. 2480, the Uranium Enrichment Reorganization Act, which would restructure DOE's uranium enrichment program as a government corporation. Specifically, this legislation would allow the corporation to set prices to maximize long-term returns; establish a fund to meet future decontamination, decommissioning, and remedial action costs associated with past uranium enrichment activities. and require the government to pay its share of the costs to clean up mining waste generated under past government contracts. GAO believes that H.R. 2480 takes needed steps toward establishing clear objectives for the enrichment program and would allow the new corporation to better operate as a business entity. The bill would also resolve several long-term issues that seriously challenge the program's future, including the need to pay billions of dollars in environmental and decommissioning costs at a time when competition is expected to increase. However, GAO believes that the bill could be strengthened by including a specific cost recovery provision. Because DOE projects that the corporation's future earnings could be substantial, GAO suggests that Congress require the repayment of $3 billion, rather than rely solely on unspecified dividends and/or uncertain future stock sales that may not materialize unless problems related to licensing uncertainties, increased competition, and billions of dollars in liabilities are adequately resolved

  10. Nuclear energy: Environmental issues at DOE's nuclear defense facilities

    International Nuclear Information System (INIS)

    1986-01-01

    GAO's review of nine Department of Energy defense facilities identified a number of significant environmental issues: (1) eight facilities have groundwater contaminated with radioactive and/or hazardous substances to high levels; (2) six facilities have soil contamination in unexpected areas, including offsite locations; (3) four facilities are not in full compliance with the Clean Water Act; and (4) all nine facilities are significantly changing their waste disposal practices to obtain a permit under the Resource Conservation and Recovery Act. GAO is recommending that DOE develop and overall groundwater and soil protection strategy that would provide a better perspective on the environmental risks and impacts associated with operating DOE's nuclear defense facilities. GAO also recommends that DOE allow outside independent inspections of the disposal practices used for any waste DOE self-regulates and revise its order governing the management of hazardous and mixed waste

  11. Photodetachment cross-section of in a three-dimensional cubical ...

    Indian Academy of Sciences (India)

    DE-HUA WANG

    2017-10-19

    Oct 19, 2017 ... DE-HUA WANG. ∗. , PANG-ZHI .... on the surfaces along x, y, z directions, respectively. Then the ..... [20] Y Han, L F Wang, S Y Ran and G C Yang, Physica B. 405, 3082 ... [36] D H Wang, Y J Yu and S L Lin, Chin. Opt. Lett.

  12. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. LIANG WANG. Articles written in Journal of Genetics. Volume 92 Issue 3 December 2013 pp 395-402 Research Article. Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene × gender interaction · Ke-Sheng Wang Liang Wang Xuefeng Liu Min Zeng.

  13. Comportamento de 16 porta-enxertos para o tangor Murcott na região de Itirapina-SP Behavior of sixteen rootstocks for Murcott in Itirapina, SP, Brazil

    Directory of Open Access Journals (Sweden)

    José Orlando de Figueiredo

    2006-04-01

    Full Text Available Foi monitorado o comportamento de 16 porta-enxertos para o tangor Murcott [Citrus reticulata Blanco x C. sinensis (L. Osbeck], do clone nucelar J, em experimento instalado em 1990, na Fazenda Raio de Sol, Itirapina-SP. Os porta-enxertos foram: tangelo 'Orlando' (C. reticulata Blanco x C. paradisi Macf., laranja 'Caipira DAC' [C. sinensis (L. Osbeck], limão 'Cravo'(C. limonia Osbeck, os trifoliatas 'Kryder 8-5'e 'EEL'[Poncirus trifoliata (L. Raf.] e as tangerinas 'Cleópatra' (C. reshni hort. ex. Tanaka, 'Sunki' [C. sunki (Hayata hort. ex. Tanaka], 'Batangas', 'Oneco', 'Swatow', 'Szinkon', 'Satsuma', 'Cravo', 'Dancy', 'Suen Kat' e 'Pook Ling Ming' (C. reticulata Blanco. As produções foram avaliadas de 1996 a 2003 e as maiores médias foram proporcionadas pelas plantas enxertadas nas tangerinas 'Cleópatra', 'Suen Kat', 'Pook Ling Ming' e 'Sunki' (>40 kg planta-1. Dentre os porta-enxetos que induziram as mais baixas produções, estão os dois trifoliatas, a 'Caipira DAC' e a tangerina 'Cravo' (Sixteen rootstocks were compared in a trial started in 1990, for Murcott tangor, nucellar clone "J", in Itirapina, Brazil. The rootstocks tested were Orlando tangelo (Citrus reticulata Blanco x C. paradisi Macf., sweet orange [C. sinensis (L. Osbeck] cv. Caipira DAC, Rangpur lime (C. limonia Osbeck, Poncirus trifoliata (L. Raf. cv. Kryder 8-5, P. trifoliata (L. Raf. cv. EEL and the mandarins Cleopatra (C. reshni hort. ex. Tanaka, Sunki [C. sunki (Hayata hort. ex. Tanaka] and Batangas, Oneco, Swatow, Szinkon, Satsuma, Cravo, Dancy, Suen Kat and Pook Ling Ming (C. reticulata Blanco. Fruit yield was measured per plant, in a period of seven years (1996-2003. The best yielding rootstocks were Cleopatra, Suen Kat, Pook Ling Ming and Sunki mandarins (> 40 kg tree-1. The two Trifoliate, sweet orange cv. Caipira DAC and Cravo mandarin presented the lowest yields (< 25 kg tree-1. No significant variation was observed for fruit quality characteristics of trees on

  14. Landmine Warfare in Support of Multi-domain Battle: Balancing Discrimination and Military Effectiveness

    Science.gov (United States)

    2017-05-25

    31 Government Accountability Office, “Military Operations: Information on US Use of Land Mines in the Persian Gulf War” (GAO-02...James T. Cobb, “Is Field Artillery Prepared?” 35-37. 67 Sean MacFarland, Michael Shields, and Jeffery Snow, “The King and I: The Impending Crisis in...2006. Government Accountability Office. GAO-02-1003, Military Operations: Information on US Use of Land Mines in the Persian Gulf War. Washington

  15. Security Clearances: Additional Mechanisms May Aid Federal Tax-Debt Detection

    Science.gov (United States)

    2015-03-18

    it is requesting disclosure , and, as such, the agency may not obtain the complete tax -debt history of the individual nor would it be of use during...BagdoyanS@gao.gov. Contact points for our Offices of Congressional Relations and Public Affairs may be found on the last page of this statement...Connect with GAO To Report Fraud, Waste, and Abuse in Federal Programs Congressional Relations Public Affairs Please Print on Recycled Paper.

  16. Proliferative Activity and Neuroprotective Effect of Ligustrazene ...

    African Journals Online (AJOL)

    Proliferative Activity and Neuroprotective Effect of. Ligustrazene Derivative by Irritation of Vascular. Endothelial Growth Factor Expression in Middle Cerebral. Artery Occlusion Rats. Zhang Huazheng1, Wang Penglong2, Ren Liwei1, Wang Xiaobo2, Li Guoliang2,. Wang Mina1, Chu Fuhao2, Gong Yan2, Xu Bing2, Bi Siling1, ...

  17. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. Jinping Wang. Articles written in Journal of Genetics. Volume 91 Issue 3 December 2012 pp 303-312 Research Article. Conditional QTL mapping of protein content in wheat with respect to grain yield and its components · Lin Wang Fa Cui Jinping Wang Li Jun Anming Ding Chunhua ...

  18. Wang Haili, The History of Egypt

    Institute of Scientific and Technical Information of China (English)

    Han Jianwei[1

    2015-01-01

    The History of Egypt is the first monograph on Egyptian history written by a single Chinese author. As a comprehensive study both in Egyptology and in Egyptian history, it represents a new level of Egyptian historical research in Chinese academia.

  19. DONG JIE Zhang, LIANG Wang, ZHON

    Indian Academy of Sciences (India)

    User

    development, hairless nude skin, and short life (Abitbol et al., 2015; Bryson et al., 2013). On the ... Foxn1 maintains TECs to support T-cell development via mcm2 ... were ligated upstream of the firefly luciferase gene in the plasmid pGL3-Basic.

  20. Genetics Home Reference: 3q29 microduplication syndrome

    Science.gov (United States)

    ... Schmidt KR, Tervo R, Escobar LF, Friedrich CA, McDonald M, Campbell L, Ming JE, Zackai EH, Bejjani ... 10 All Bulletins Features What is direct-to-consumer genetic testing? What are genome editing and CRISPR- ...

  1. Genetics Home Reference: 3q29 microdeletion syndrome

    Science.gov (United States)

    ... Schmidt KR, Tervo R, Escobar LF, Friedrich CA, McDonald M, Campbell L, Ming JE, Zackai EH, Bejjani ... 10 All Bulletins Features What is direct-to-consumer genetic testing? What are genome editing and CRISPR- ...

  2. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. YANG LUO. Articles written in Journal of Genetics. Volume 90 Issue 2 August 2011 pp 339-342 Research Note. Novel vitamin D 1-hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient · Lihua Cao Fang Liu Yu Wang Jian Ma Shusen Wang Libo Wang ...

  3. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Conditional QTL mapping of protein content in wheat with respect to grain yield and its components · Lin Wang Fa Cui Jinping Wang Li Jun ... The association study of nonsyndromic cleft lip with or without cleft palate identified risk variants of the GLI3 gene in a Chinese population · YIRUI WANG YIMIN SUN YONGQING ...

  4. Resource-Bounded Information Acquisition and Learning

    Science.gov (United States)

    2012-05-01

    Different combinations of voting and confidence evaluation schemes...H. Wang, ... Facial Expression Decomposition..., ICCV, 2003. (E)..., H. Wang, ... Tensor Approximation..., SIGGRAPH. 2005. (F)..., H. Wang, ... High...two of the possible schemes for combining the evidence in the output space. In the first scheme, we take a majority 67 vote , i.e., the class with the

  5. HOTEL INFORMATION

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Tiantan Hotel Wang Ping has been named as assistant general manager of Tiantan Hotel. With a Master's degree, Wang has more than 20 years of experience in hotel management, having served as department manager, assistant general manager and vice general manager in various hospitality establishments. Wang published an article on hotel management and mar-

  6. Browse Title Index

    African Journals Online (AJOL)

    Items 501 - 550 of 1309 ... HH Tamboura, B Bayala, M Lompo, IP Guissou, L Sawadogo ... X Wang, Y-G Chen, L Ma, Z-H Li, J-Y Li, X-G Liu, J-L Zou, J-H Wu. Vol 11, No 2 ... Zhi-Jiang Wang, Wei Xu, Jian-Wen Liang, Cai-Sheng Wang, Yani Kang.

  7. Phenology-based Spartina alterniflora mapping in coastal wetland of the Yangtze Estuary using time series of GaoFen satellite no. 1 wide field of view imagery

    Science.gov (United States)

    Ai, Jinquan; Gao, Wei; Gao, Zhiqiang; Shi, Runhe; Zhang, Chao

    2017-04-01

    Spartina alterniflora is an aggressive invasive plant species that replaces native species, changes the structure and function of the ecosystem across coastal wetlands in China, and is thus a major conservation concern. Mapping the spread of its invasion is a necessary first step for the implementation of effective ecological management strategies. The performance of a phenology-based approach for S. alterniflora mapping is explored in the coastal wetland of the Yangtze Estuary using a time series of GaoFen satellite no. 1 wide field of view camera (GF-1 WFV) imagery. First, a time series of the normalized difference vegetation index (NDVI) was constructed to evaluate the phenology of S. alterniflora. Two phenological stages (the senescence stage from November to mid-December and the green-up stage from late April to May) were determined as important for S. alterniflora detection in the study area based on NDVI temporal profiles, spectral reflectance curves of S. alterniflora and its coexistent species, and field surveys. Three phenology feature sets representing three major phenology-based detection strategies were then compared to map S. alterniflora: (1) the single-date imagery acquired within the optimal phenological window, (2) the multitemporal imagery, including four images from the two important phenological windows, and (3) the monthly NDVI time series imagery. Support vector machines and maximum likelihood classifiers were applied on each phenology feature set at different training sample sizes. For all phenology feature sets, the overall results were produced consistently with high mapping accuracies under sufficient training samples sizes, although significantly improved classification accuracies (10%) were obtained when the monthly NDVI time series imagery was employed. The optimal single-date imagery had the lowest accuracies of all detection strategies. The multitemporal analysis demonstrated little reduction in the overall accuracy compared with the

  8. Verification of the utility of molecular markers linked to the multiple ...

    African Journals Online (AJOL)

    GREGORY

    2010-08-30

    Aug 30, 2010 ... Feng Hui*, Wang Lili, Wei Peng, Liu Zhiyong, Li Chengyu, Wang Yugang, Ji Ruiqin and Zhang. Huaqing ..... Chin. Agric. Sci. Bull. 22: 377-379. Li CY, Feng H, Wei P, Wang LL, Zhang J, Yang HN, Jiang N (2009). Directional transfer of the genic multiple allele inherited male sterile line in Chinese cabbage.

  9. Antioxidant and Anti-proliferative Activities of Flavonoids from ...

    African Journals Online (AJOL)

    significant growth inhibitory effect on RKO cells with IC50 of 39.08 μmol/L and 17.68 μmol/L, respectively ..... YJ.. Essential oil from rhizomes of Ligusticum chuanxiong induces apoptosis in hypertrophic scar ... Liu H, Mou Y, Zhao J, Wang J, Zhou L, Wang M, Wang. D, Han J, Yu Z, Yang F. Flavonoids from Halostachys.

  10. F F Sun

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. F F Sun. Articles written in Bulletin of Materials Science. Volume 37 Issue 1 February 2014 pp 71-76. Study of electroless copper plating on ABS resin surface modified by heterocyclic organosilane self-assembled film · H N Zhang J Wang F F Sun D Liu H Y Wang F Wang.

  11. On the world stage | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-07-08

    social capital,” such as mutual assistance and civic participation, in helping ... Lu Ming's paper has also been accepted for publication in a forthcoming issue of CESifo Economic Studies, produced by one of Europe's foremost ...

  12. Defense Management: Further Analysis Needed to Identify Guam’s Public Infrastructure Requirements and Costs for DOD’s Realignment Plan

    Science.gov (United States)

    2013-12-01

    47U.S. Department of the Interior Office of Inspector General, Tax Collection Activities Government of Guam: Revitalized Tax...A-11: Planning, Budgeting, and Acquisition of Capital Assets, app . 8 (ver. 3.0 (July 2013). 62GAO-09-3SP, pp. i and 182. DOD’s Cost Estimate to...Capital Assets, app . 8 (V 3.0 July 2013). According to our cost estimating guide, a reliable cost estimate is critical to successfully 64GAO-09-3SP

  13. Veterans Health Care: Improvements Needed in Operationalizing Strategic Goals and Objectives

    Science.gov (United States)

    2016-10-01

    sess. (2016) (statement of Robert McDonald , Secretary, U.S. Department of Veterans Affairs). The other priorities include delivering a unified veteran...posted products, go to http://www.gao.gov and select “E-mail Updates.” The price of each GAO publication reflects GAO’s actual cost of production...and distribution and depends on the number of pages in the publication and whether the publication is printed in color or black and white. Pricing and

  14. Atomic Scale Picture of the Ion Conduction Mechanism in Tetrahedral Network of Lanthanum Barium Gallate

    Energy Technology Data Exchange (ETDEWEB)

    Jalarvo, Niina H [ORNL; Gourdon, Olivier [ORNL; Bi, Zhonghe [ORNL; Gout, Delphine J [ORNL; Ohl, Michael E [ORNL; Paranthaman, Mariappan Parans [ORNL

    2013-01-01

    Combined experimental study of impedance spectroscopy, neutron powder diffraction and quasielastic neutron scattering was performed to shed light into the atomic scale ion migration processes in proton and oxide ion conductor; La0.8Ba1.2GaO3.9 . This material consist of tetrahedral GaO4 units, which are rather flexible and rocking motion of these units promotes the ionic migration process. The oxide ion (vacancy) conduction takes place on channels along c axis, involving a single elementary step, which occurs between adjacent tetrahedron (inter-tetrahedron jump). The proton conduction mechanism consists of intra-tetrahedron and inter-tetrahedron elementary processes. The intra-tetrahedron proton transport is the rate-limiting process, with activation energy of 0.44 eV. The rocking motion of the GaO4 tetrahedron aids the inter-tetrahedral proton transport, which has the activation energy of 0.068 eV.

  15. Nuclear safety and health

    International Nuclear Information System (INIS)

    England-Joseph, J.A.

    1991-03-01

    The full extent of nonconforming parts usage in the federal government is unknown. However, large and small companies, both foreign and domestic, have sold nonconforming parts-including counterfeit and substandard items-to nuclear power plants, commercial and military aircraft, naval ships, weapons systems, and the space shuttle. Accidents resulting from the failure of nonconforming parts could be devastating, GAO testified. To eliminate this problem, GAO believes that an aggressive, government wide approach is needed, one that would ensure that federal agencies cooperate and share information about nonconforming products. This paper reports that while a centralized information system may not stop the proliferation of nonconforming products, it should help federal agencies make informed decisions about potential suppliers and products. GAO concludes that the Office of Management and Budget is in the best position to develop an effective, appropriate, and cost-beneficial plan to help resolve the problem of nonconforming parts

  16. AHP 40: Review: CHINA FROM EMPIRE TO NATION-STATE

    Directory of Open Access Journals (Sweden)

    Tristan G Brown

    2016-02-01

    Full Text Available Michael Gibbs Hill's excellent translation of the introduction to Wang Hui's four-volume opus, The Rise of Modern Chinese Thought 现代中 国思想的兴起 provides a substantial contribution to scholars of China and intellectual historians by bringing another of Wang Hui's critical works into English (for other such examples, see Wang and Huters 2003 and 2011. The task of translating could not have been easy, as Wang Hui frequently cites works from Chinese antiquity and translated texts from abroad, making Hill's results truly exceptional. The translation is accessible and painstakingly executed, with many important phrases explained for non-specialists alongside transliterated key terms. The Rise of Modern Chinese Thought demonstrates the need for translation work in the fields of area studies by making the important works of non-English speakers available to Anglophone audiences. As Zhang Yongle pointed out in his review on the work in toto, "It can safely be said that nothing comparable to Wang Hui's work has appeared in China since the late Qing-early Republican period" (Zhang 2010:71. Wang Hui, while exploring the links between China and its past through the country's rich intellectual traditions, manages to deftly discuss China in global terms and historical contexts. Hill's helpful introduction contextualizes Wang's writing style in the zeitgeist of the post Tiananmen period from 1990 to 2010. ...

  17. Ethylene- and diethylene glycol metabolism, toxicity and treatment

    International Nuclear Information System (INIS)

    Wiener, H.L.

    1986-01-01

    Each year numerous men and domestic animals suffer from ethylene glycol (EG) poisoning. The present approach to treating EG poisoning by administering ethanol is aimed at preventing the oxidation of EG to glycolate, the toxic mediator. When treatment is delayed or the amount of EG consumed is large, successful treatment is rarely obtained, since the concentration of glycolate becomes excessive. In an effort to develop a better approach to treating EG poisoning, studies were conducted to determine the feasibility of using pig liver glycolic acid oxidase (GAO) as a means of enzyme therapy in male rats receiving EG. Pig liver GAO was active in vitro in rat blood, oxidizing glycolate to glyoxylate. When injected intravenously into male rats, GAO had an approximate half-life of twenty five minutes and its elimination followed first order kinetics. Despite activity in vitro, native pig liver GAO did not display detectable activity in vivo. Diethylene glycol (DEG) when ingested also results in toxicity. The metabolism and toxicity of DEG was investigated in male Wistar rats using [ 14 C]-DEG synthesized from [U- 14 C]-EG and ethylene oxide and purified by high performance liquid chromatography. (2-Hydroxyethoxy)acetic acid (HEAA) was identified as the major product of DEG oxidation. These results suggest that the treatment of DEG poisoning should follow the same regimen as treatment for EG poisoning

  18. Earth fissures in Qinglong Graben in Yuncheng Basin, China

    Indian Academy of Sciences (India)

    Jianwei Qiao

    2018-02-14

    Feb 14, 2018 ... Key Laboratory of Western China Mineral Resources and Geological Engineering, Xi'an 710 054, Shaanxi, China. *Corresponding .... first to appear in edge and then extended to the center. ..... Miao D Y, Li Y L, Lv S H, Tian J M, Wang Y R and Si ... Wang J M, Wang C M and Liu K 2001 Progress in ground.

  19. Browse Title Index

    African Journals Online (AJOL)

    Items 7351 - 7400 of 11090 ... Vol 10, No 65 (2011), Molecular cloning and sequence analysis of VP6 gene of giant panda rotavirus strain CH-1, Abstract PDF. Y Lie, S Chen, CD Wang, Z Zhang, CD Wang, W Guo, X Wang, L Guo, Q Yan. Vol 11, No 23 (2012), Molecular cloning, characterization and expression analysis of heat ...

  20. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; Department of Mechanical Engineering, Ming Chi University of Technology, Taipei, Taiwan; Department of Orthopaedic Surgery, School of Medicine, National Taiwan University, Taipei, Taiwan; Department of Mechanical Engineering, Lunghwa ...

  1. 21. sajandi hiina laine ja minimalistlik interjöör / Leila Pärtelpoeg

    Index Scriptorium Estoniae

    Pärtelpoeg, Leila, 1927-

    2006-01-01

    Nüüdisaegne minimalism ja Hiina Ming dünastia aegadest pärinev materjalikäsitlus ühilduvad moodsas hiinalikus interjööris. Sisekujundus: Leila Pärtelpoeg. Stilist Madis Liplap. 6 ill, 5 värv.

  2. Electron paramagnetic resonance parameters and local structure for ...

    Indian Academy of Sciences (India)

    HUA-MING ZHANG. 1. , GUANG-DUO LU. 1 ... the above ZFSs, the local structure information for the impurity Gd. 3+ is obtained, i.e., .... parameters, extended X-ray absorption fine-structure (EXAFS) measurements and crystal-field spectrum ...

  3. Development of neutron detectors and neutron radiography at ...

    Indian Academy of Sciences (India)

    BARC, Department of Atomic Energy units and some universities and research institutes in India and .... by Solid State Physics Division for various applications, using the 400 kW swim- ming pool type reactor, Apsara as the neutron source.

  4. Irinotecan and 5-fluorouracil-co-loaded, hyaluronic acid-modified layer-by-layer nanoparticles for targeted gastric carcinoma therapy

    Directory of Open Access Journals (Sweden)

    Gao Z

    2017-09-01

    Full Text Available Zhuanglei Gao,1 Zhaoxia Li,2 Jieke Yan,3 Peilin Wang1 1Department of General Surgery, 2Department of Pediatrics, 3Department of Renal Transplantation, The Second Hospital of Shandong University, Jinan, Shandong, People’s Republic of China Abstract: For targeted gastric carcinoma therapy, hyaluronic acid (HA-modified layer-by-layer nanoparticles (NPs are applied for improving anticancer treatment efficacy and reducing toxicity and side effects. The aim of this study was to develop HA-modified NPs for the co-loading of irinotecan (IRN and 5-fluorouracil (5-FU. A novel polymer–chitosan (CH–HA hybrid formulation (HA–CH–IRN/5-FU NPs consisting of poly(D,L-lactide-co-glycolide (PLGA and IRN as the core, CH and 5-FU as a shell on the core and HA as the outmost layer was prepared. Its morphology, average size, zeta potential and drug encapsulation ability were evaluated. Human gastric carcinoma cells (MGC803 cells and cancer-bearing mice were used for the testing of in vitro cytotoxicity and in vivo antitumor efficiency of NPs. HA–CH–IRN/5-FU NPs displayed enhanced antitumor activity in vitro and in vivo than non-modified NPs, single drug-loaded NPs and drugs solutions. The results demonstrate that HA–CH–IRN/5-FU NPs can achieve impressive antitumor activity and the novel targeted drug delivery system offers a promising strategy for the treatment of gastric cancer. Keywords: gastric carcinoma, irinotecan, 5-fluorouracil, hyaluronic acid, layer-by-layer nanoparticles

  5. Lanchester-Type Models of Warfare. Volume II

    Science.gov (United States)

    1980-10-01

    ii7 L HOWES and THRALL (1972) ,HT n HTY HT m HTX jini ijl HOLTER (1973) and ANDERSON (1979) CHA HAx Y tAs in the preceding table, SPUDICH (1968) - the...detail can one afford? A recent U. S. General Accounting Office ( GAO ) report [150, pp. 28-29] points out that there is a strong inconsistency between...further details). 65. A recent U. S. Getueral Accounting Office ( GAO ) [1501 study has emphasized that empirical study is necessary to strengthen the

  6. Remote Possibilities: Explaining Innovations in Airpower

    Science.gov (United States)

    2012-06-01

    GAO-06-391), March 2006, 67 available at htp ://www.gao.gov/new.items/d06391.pdf]. The U.S. Air Force lists the jet’s price tag as $143M, but that...Board’s pronouncement, Air Force Manual 1-8, Strategic Air Operations, stated the manned bomber was the “primary offensive manifestation of national power...surface-to-surface missiles. The Air Force interpreted this as a victory, reasoning that since it had the strategic bombardment mission, it was the

  7. Additional improvements needed in physical security at nuclear powerplants

    International Nuclear Information System (INIS)

    1983-01-01

    Since the middle 1970's, the Nuclear Regulatory Commission and powerplant operators have taken measures to reduce the vulnerability of powerplants to attempted acts of sabotage. GAO's evaluation disclosed that further improvements can be made by screening nuclear plant employees to reduce the number of potential saboteurs and strengthening the physical security systems to ensure their compatibility with other plant safety systems. The Commission has taken two initiatives addressing these improvements. Therefore, GAO is not making recommendations at this time

  8. Properties and structure of Faraday rotating glasses for magneto optical current transducer

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Q.; Ma, Q.; Wang, H.; Wang, Q.; Hao, Y.; Chen, Q.

    2017-07-01

    High heavy metal oxides (60–100mol.%) ternary PbO–Bi2O3–B2O3 (PBB) glasses were fabricated and characterized. Using a homemade single lightway DC magnetic setup, Verdet constants of PBB glasses were measured to be 0.0923–0.1664min/G cm at 633nm wavelengths. Glasses with substitution of PbO by Bi2O3 were studied in terms of their Faraday effects. PbO–Bi2O3–B2O3 = 50–40–10mol.% exhibited good thermal stability, high Verdet constant (0.1503min/G cm) and good figure of merit (0.071). Based on this glass, a magneto optical current sensor prototype was constructed and its sensitivity at different currents was evaluated to be 8.31nW/A. © 2. (Author)

  9. Epigenetic game theory and its application in plants. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Zhang, Yuan-Ming; Zhang, Yinghao; Guo, Mingyue

    2017-03-01

    Wang's et al. article [1] is the first to integrate game theory (especially evolutionary game theory) with epigenetic modification of zygotic genomes. They described and assessed a modeling framework based on evolutionary game theory to quantify, how sperms and oocytes interact through epigenetic processes, to determine embryo development. They also studied the internal mechanisms for normal embryo development: 1) evolutionary interactions between DNA methylation of the paternal and maternal genomes, and 2) the application of game theory to formulate and quantify how different genes compete or cooperate to regulate embryogenesis through methylation. Although it is not very comprehensive and profound regarding game theory modeling, this article bridges the gap between evolutionary game theory and the epigenetic control of embryo development by powerful ordinary differential equations (ODEs). The epiGame framework includes four aspects: 1) characterizing how epigenetic game theory works by the strategy matrix, in which the pattern and relative magnitude of the methylation effects on embryogenesis, are described by the cooperation and competition mechanisms, 2) quantifying the game that the direction and degree of P-M interactions over embryo development can be explained by the sign and magnitude of interaction parameters in model (2), 3) modeling epigenetic interactions within the morula, especially for two coupled nonlinear ODEs, with explicit functions in model (4), which provide a good fit to the observed data for the two sexes (adjusted R2 = 0.956), and 4) revealing multifactorial interactions in embryogenesis from the coupled ODEs in model (2) to triplet ODEs in model (6). Clearly, this article extends game theory from evolutionary game theory to epigenetic game theory.

  10. One scholar's story | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-07-08

    Jul 8, 2011 ... ... in China, with enormous regional differences and rural-urban dualism, and ... Lu Ming credits the Poverty Research Network with playing a part in his ... CASE STUDY: Nepal — A cleaner city and better health in Kathmandu.

  11. Nobel laureate in literature visits CERN

    CERN Multimedia

    Anaïs Schaeffer

    2015-01-01

    Gao Xingjian, winner of the Nobel Prize for Literature in 2000, was invited to visit CERN as part of European Researchers’ Night. During his visit to the Laboratory, he took time out to give us a dose of his optimism.   Gao Xingjian in IdeaSquare's bus during his visit to CERN.   “The idea of bringing scientists and artists together is wonderful!” An enthusiastic first-time visitor to the Laboratory, Gao Xingjian regaled his audience with his thoughts on human reality at the conference 'Made of Shadow and Light', in which he took part on 24 September, alongside Sergio Bertolucci, CERN’s Director for Research and Computing. Interested in science since his childhood (his marks in physics and maths at school were excellent, he explains with a smile), he draws an interesting parallel between human consciousness and dark matter: “The concept of dark matter makes complete sense to me,”&nbs...

  12. Novel Power Flow Problem Solutions Method’s Based on Genetic Algorithm Optimization for Banks Capacitor Compensation Using an Fuzzy Logic Rule Bases for Critical Nodal Detections

    Directory of Open Access Journals (Sweden)

    Nasri Abdelfatah

    2011-01-01

    Full Text Available The Reactive power flow’s is one of the most electrical distribution systems problem wich have great of interset of the electrical network researchers, it’s  cause’s active power transmission reduction, power losses decreasing, and  the drop voltage’s increase. In this research we described the efficiency of the FLC-GAO approach to solve the optimal power flow (OPF combinatorial problem. The proposed approach employ tow algorithms, Fuzzy logic controller (FLC algorithm for critical nodal detection and gentic algorithm  optimization (GAO algorithm for optimal seizing capacitor.GAO method is more efficient in combinatory problem solutions. The proposed approach has been examined and tested on the standard IEEE 57-bus the resulats show the power loss minimization denhancement, voltage profile, and stability improvement. The proposed approach results have been compared to those that reported in the literature recently. The results are promising and show the effectiveness and robustness of the proposed approach.

  13. Characterization of potential zones of dust generation at eleven stations in the southern Sahara

    Science.gov (United States)

    Clark, I.; Assamoi, P.; Bertrand, J.; Giorgi, F.

    Synoptic wind data for multi-decadal periods at eleven stations located in the southern Sahara region (Agadez, Atar, Bilma, Dori, Gao, Kayes, Nema, Niamey, Nouadhibou, Ouagadougou and Tessalit) are used to study the monthly dust deflation power over the region. We found that, regardless of the conditions of the soil, the deflation power (or wind efficiency) is not sufficient to generate significant amounts of aerosols south of 15°N. North of this latitude, the deflation power is much larger, with potential zones of either very strong deflation (Nouadhibou and Bilma) or severe deflation (Gao, Tessalit, Nema, Atar, Agadez). Stations in the Sahel region such as Gao, Agadez and Tessalit are characterized by a gradual reinforcement of the deflation power between 1970 and 1984 in correspondence of increasing desertification over the region. During this same period, Bilma, a well know region of dust source, experienced a major reduction in deflation power due to shifts in large scale wind patterns.

  14. Rapid adaptation of activated sludge bacteria into a glycogen accumulating biofilm enabling anaerobic BOD uptake.

    Science.gov (United States)

    Hossain, Md Iqbal; Paparini, Andrea; Cord-Ruwisch, Ralf

    2017-03-01

    Glycogen accumulating organisms (GAO) are known to allow anaerobic uptake of biological oxygen demand (BOD) in activated sludge wastewater treatment systems. In this study, we report a rapid transition of suspended activated sludge biomass to a GAO dominated biofilm by selective enrichment using sequences of anaerobic loading followed by aerobic exposure of the biofilm to air. The study showed that within eight weeks, a fully operational, GAO dominated biofilm had developed, enabling complete anaerobic BOD uptake at a rate of 256mg/L/h. The oxygen uptake by the biofilm directly from the atmosphere had been calculated to provide significant energy savings. This study suggests that wastewater treatment plant operators can convert activated sludge systems readily into a "passive aeration" biofilm that avoids costly oxygen transfer to bulk wastewater solution. The described energy efficient BOD removal system provides an opportunity to be coupled with novel nitrogen removal processes such as anammox. Copyright © 2016. Published by Elsevier Ltd.

  15. Comparison of zero-profile anchored spacer versus plate-cage construct in treatment of cervical spondylosis with regard to clinical outcomes and incidence of major complications: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Liu WJ

    2015-09-01

    Full Text Available Weijun Liu,1,* Ling Hu,2,* Junwen Wang,1 Ming Liu,1 Xiaomei Wang3 1Department of Orthopedics, Pu Ai Hospital, Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 2Department of Anesthesiology, Tianyou Hospital, Affiliated to Wuhan University of Science and Technology, 3Department of Biological Science and Technology, Wuhan Bioengineering Institute, Wuhan, People’s Republic of China *These authors contributed equally to this work Purpose: Meta-analysis was conducted to evaluate whether zero-profile anchored spacer (Zero-P could reduce complication rates, while maintaining similar clinical outcomes compared to plate-cage construct (PCC in the treatment of cervical spondylosis. Methods: All prospective and retrospective comparative studies published up to May 2015 that compared the clinical outcomes of Zero-P versus PCC in the treatment of cervical spondylosis were acquired by a comprehensive search in PubMed and EMBASE. Exclusion criteria were non-English studies, noncomparative studies, hybrid surgeries, revision surgeries, and surgeries with less than a 12-month follow-up period. The main end points including Japanese Orthopedic Association (JOA and Neck Disability Index (NDI scores, cervical lordosis, fusion rate, subsidence, and dysphagia were analyzed. All studies were analyzed with the RevMan 5.2.0 software. Publication biases of main results were examined using Stata 12.0. Results: A total of 12 studies were included in the meta-analysis. No statistical difference was observed with regard to preoperative or postoperative JOA and NDI scores, cervical lordosis, and fusion rate. The Zero-P group had a higher subsidence rate than the PCC group (P<0.05, risk difference =0.13, 95% confidence interval [CI] 0.00–0.26. However, the Zero-P group had a significantly lower postoperative dysphagia rate than the PCC group within the first 2 weeks (P<0.05, odds ratio [OR] =0.64, 95% CI 0.45–0.91, at the 6th month [P

  16. LincRNA-ROR promotes metastasis and invasion of esophageal squamous cell carcinoma by regulating miR-145/FSCN1

    Directory of Open Access Journals (Sweden)

    Shang M

    2018-01-01

    Full Text Available Muhe Shang, Xianghu Wang, Ying Zhang, Zhikui Gao, Tian Wang, Ran Liu Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu, China Background and objective: In an attempt to discover a new biomarker for early diagnosis and prognosis of esophageal squamous cell carcinoma (ESCC, the regulation mechanism of large intergenic non-coding RNA–regulator of reprogramming (lincRNA-ROR as a microRNA (miRNA sponge was studied.Patients and methods: ROR expression in 91 pairs of ESCC tissue samples and matched adjacent tissues was quantified with real-time fluorescent quantitative polymerase chain reaction (qRT-PCR. The ROR–miRNA–mRNA regulatory network was built with 161 esophageal cancer (EC tissues and 11 adjacent tumor tissues from The Cancer Genome Atlas (TCGA database. A total of 96 cases of ESCC from TCGA database were collected for analysis on survival rates. The regulatory relationship between ROR, miR-145 and FSCN1 was verified in ESCC cells via qRT-PCR, dual luciferase reporter (DLR assay, RNA immunoprecipitation (RIP and Western blotting. The transwell method was used to detect cell migration and invasion.Results: ROR expression in ESCC tumor tissues was significantly higher than in the adjacent tissues, p<0.001. The survival rate of ESCC patients with high ROR expression levels was lower than that of patients with low ROR expression levels (p<0.001. ROR overexpression could downregulate miR-145 by up to 50% was proven by RIP, DLR assay, and qRT-PCR. Two effective binding sites of ROR to miR-145 were verified by DLR assay. One of the sites has never been cited in the literature. The Western blotting results showed that FSCN1 was a downstream target of ROR/miR-145 (p<0.05. Transwell assays were used to show that overexpression of ROR enhanced migration and invasion behavior of ESCC and miR-145 hindered these effects.Conclusion: ROR acted as a competitive

  17. In vitro characterization and in vivo evaluation of nanostructured lipid curcumin carriers for intragastric administration

    Directory of Open Access Journals (Sweden)

    Fang M

    2012-10-01

    Full Text Available Min Fang, Yilin Jin, Wei Bao, Hui Gao, Mengjin Xu, Di Wang, Xia Wang, Ping Yao, Liegang LiuDepartment of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, and Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, People’s Republic of ChinaBackground: Curcumin has a variety of pharmacological effects. However, poor water solubility and low oral bioavailability limit its clinical utility. A delivery system for nanostructured lipid carriers has been reported to be a promising approach to enhancing the oral absorption of curcumin. The aim of the present study was to investigate the pharmacokinetics, tissue distribution, and relative bioavailability of curcumin in rats after a single intragastric dose of a nanostructured lipid curcumin carrier formulation.Methods: Nanostructured lipid curcumin carriers were prepared using the ethanol dripping method and characterized in terms of the particle size, polydispersity index, zeta potential, differential scanning calorimetry, drug-loading capacity, encapsulation efficiency, and in vitro release. The pharmacokinetics and tissue distribution of nanostructured lipid curcumin carriers and curcumin suspension were compared after intragastric administration.Results: Nanostructured lipid curcumin carriers showed a significantly higher peak plasma concentration (564.94 ± 14.98 ng/mL versus 279.43 ± 7.21 ng/mL, P < 0.01, a shorter time taken to reach peak plasma concentration (0.5 ± 0.01 hour versus 1.0 ± 0.12 hour, P < 0.01, and a greater AUC0–∞ (820.36 ± 25.11 mg × hour/L versus 344.11 ± 10.01 mg × hour/L, P < 0.05 compared with curcumin suspension. In the tissue distribution studies, curcumin could be detected in the spleen, heart, liver, kidneys, lungs, and brain. Following intragastric administration of the nanostructured lipid curcumin

  18. Biocompatibility of Fe3O4@Au composite magnetic nanoparticles in vitro and in vivo

    Directory of Open Access Journals (Sweden)

    Li Y

    2011-11-01

    Full Text Available Yuntao Li1,2, Jing Liu1, Yuejiao Zhong3, Jia Zhang1, Ziyu Wang1, Li Wang1, Yanli An1, Mei Lin1, Zhiqiang Gao2, Dongsheng Zhang11School of Medicine, Southeast University, Nanjing, Jiangsu Province, People's Republic of China; 2Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, People's Republic of China; 3Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research, Nanjing, Jiangsu Province, People's Republic of ChinaPurpose: This research was conducted to assess the biocompatibility of the core-shell Fe3O4@Au composite magnetic nanoparticles (MNPs, which have potential application in tumor hyperthermia. Methods: Fe3O4@Au composite MNPs with core-shell structure were synthesized by reduction of Au3+ in the presence of Fe3O4-MNPs prepared by improved co-precipitation. Cytotoxicity assay, hemolysis test, micronucleus (MN assay, and detection of acute toxicity in mice and beagle dogs were then carried out.Results: The result of cytotoxicity assay showed that the toxicity grade of this material on mouse fibroblast cell line (L-929 was classified as grade 1, which belongs to no cytotoxicity. Hemolysis rates showed 0.278%, 0.232%, and 0.197%, far less than 5%, after treatment with different concentrations of Fe3O4@Au composite MNPs. In the MN assay, there was no significant difference in MN formation rates between the experimental groups and negative control (P > 0.05, but there was a significant difference between the experimental groups and the positive control (P < 0.05. The median lethal dose of the Fe3O4@Au composite MNPs after intraperitoneal administration in mice was 8.39 g/kg, and the 95% confidence interval was 6.58-10.72 g/kg, suggesting that these nanoparticles have a wide safety margin. Acute toxicity testing in beagle dogs also showed no significant difference in body weight between the treatment groups at 1, 2, 3, and 4 weeks after liver injection and no behavioral changes. Furthermore, blood

  19. Subject Index

    Indian Academy of Sciences (India)

    user1

    Multi-Wavelength Studies on H2O Maser Host Galaxies (J. S. Zhang & J. .... N(HI) and Jet Power/Emission in AGNs (Zhongzu Wu, Minfeng Gu & Ming Zhu), 319 .... Emanuela Orrù, David Rafferty, Huub Röttgering, Anna Scaife, Aleksandar ...

  20. African Journal of Biotechnology - Vol 14, No 28 (2015)

    African Journals Online (AJOL)

    Connecting DNA Origami Structures Using the Biotin-Streptavidin Specific Binding · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. G Amoako, Z Ming, Y Rian, P Mensah-Amoah, A Twum, F Sam, 2258-2264 ...

  1. Dentocacial deformities and orthognathic surgery in an Asian population

    NARCIS (Netherlands)

    Chew, Ming Tak

    2007-01-01

    Er zijn maar weinig onderzoeksgegevens beschikbaar over het voorkomen en de behande­ling van aangezichtsafwijkingen onder de Aziatische bevolking, veroorzaakt door tandheel­kundige problemen. UMCG-promovendus Ming Tak Chew verrichtte onderzoek op dit vlak. Op basis van tandheelkundige dossiers

  2. scrotal reconstruction with a pedicled gracilis muscle flap after

    African Journals Online (AJOL)

    nonviable tissue is removed and a granulation bed suitable for .... The pedicled or free greater omental flap as well as scrotal tissue ... Bien-keem Tan, Mohammed ZulfikarRasheed,. WofflesT.L.Wu ... Honda Hsu Chih Ming Lin, Tzong-Bon Sun,.

  3. Consumer Products Advertised to Save Energy--Let the Buyer Beware.

    Science.gov (United States)

    1981-07-24

    AD-AL06 653 GENERAL ACCOUNTING OFFICE WASHINGTON DC HUMAN RESOUR--ETC F/G 5/3 CONSUMER PRODUCTS ADVERTISED TO SAVE ENERGY--LET THE BUYER BEWA-ETC...COMPTROLLER GENERAL’S CONSUMER PRODUCTS ADVERTISED REPORT TO THE CONGRESS TO SAVE ENERGY- - LET THE BUYER BEWARE D IG E ST In efforts to reduce energy costs...and comparable, GAO believes that the best ad- vice for consumers is "let the buyer beware." (See p. 42.) F’TC ’S COMMENTS FTC said that GAO

  4. Nuclear Regulatory Commission: more aggressive leadership needed

    International Nuclear Information System (INIS)

    Staats, E.B.

    1980-01-01

    The Energy Reorganization Act of 1974 which established the Nuclear Regulatory Commission required GAO to evaluate the Commission's performance by January 18, 1980. This report responds to that requirement. GAO concluded that, although improvements have been made, the Commission's nuclear regulatory performance can be characterized best as slow, indecisive, cautious - in a word, complacent. This has largely resulted from a lack of aggressive leadership as evidenced by the Commissioners' failure to establish regulatory goals, control policymaking, and most importantly, clearly define their roles in nuclear regulation

  5. Defense Infrastructure: Actions Needed to Strengthen Utility Resilience Planning

    Science.gov (United States)

    2016-11-01

    Climate change Yes 18.0 13.9 22.1 No 78.1 73.8 82.5 Don’t know 3.8 2.1 6.4 Poor condition of the infrastructure Yes 58.3 53.2 63.4 No 39.0...the pole itself – was corroded and covered with salt, dust and debris. The salt and dirt formed a conductive layer on the insulator that can create a...GAO Contact and Staff Acknowledgments Page 84 GAO-17-27 Defense Infrastructure Defense Infrastructure: Changes in Funding Priorities and

  6. The clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Zhang M

    2018-01-01

    Full Text Available Ming Zhang,1 Jingjing Tang,1 Jiafeng Yin,2 Xiaoying Wang,3 Xiangli Feng,1 Xia Yang,1 Hu Shan,1 Qiuhong Zhang,1 Jie Zhang,1 Yali Li1 1Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 2Department of Laboratory Examination, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 3Health Examination Center, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China Background: Cyclophilin A (CyPA is a secreted molecule that is regulated by inflammatory stimuli. Although inflammation has an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD, little is known regarding the relationship between serum CyPA and COPD. Methods: Ninety-three COPD patients with acute exacerbation were enrolled in the study and were reassessed during the convalescence phase. Eighty-eight controls were matched for age, gender, body mass index, smoking index and comorbidity. The basic clinical information and pulmonary function of all participants were collected. Serum levels of CyPA and other inflammation indexes were further measured. Results: Serum CyPA was significantly increased in convalescent COPD patients compared to healthy controls, and further elevated in COPD patients with acute exacerbation. Serum CyPA positively correlated with serum interleukin-6, matrix metalloproteinase-9 and high-sensitivity C-reactive protein in both the exacerbation and convalescence phases of COPD. Furthermore, it negatively correlated with percent value of forced expiratory volume in 1 second (FEV1% predicted and FEV1/forced vital capacity in convalescent COPD patients. Conclusion: These results suggest that serum CyPA can be used as a potential inflammatory biomarker for COPD and assessment of serum CyPA may reflect the severity of inflammation in COPD. Keywords: cyclophilin A, chronic obstructive pulmonary disease

  7. Historical droughts in northern Vietnam captured by variability in speleothem δ18O

    Science.gov (United States)

    Hardt, B. F.; McGee, D.; Burns, S. J.; Hieu, N.; Hieu, D. T.

    2015-12-01

    Speleothem records overlapping with the historical period offer valuable comparisons of documentary evidence with speleothem proxy data. These records provide opportunities to 'ground-truth' the paleo-record, fill in gaps in the historical record, and more confidently extent the paleo-record into deeper time. Here we present isotopic results from a stalagmite collected in northern Vietnam spanning 1200 to 1950 CE, a period with a rich historical record in Vietnam. This sample adds significantly to the relatively sparse paleoclimate record from Southeast Asia. The record includes several multi-decadal positive excursions of ≥1 per mille in calcite δ18O. A preliminary age model, based on six U/Th ages, suggests possible correspondence to noted droughts from the historical record, including the Angkor Droughts, the Ming Dynasty Drought, the Strange Parallels Drought, and the Victorian Holocaust Drought. As modeling studies indicate a strong correlation between rainfall δ18O and both the intensity of summer monsoon winds and summer rainfall over northern Vietnam (e.g., Liu et al., 2014), these excursions are consistent with a decrease in regional precipitation. The Vietnam record shows an overall negative trend during the Little Ice Age. The study site is located well south of the westerly wind belt, ruling out a shift between monsoonal and mid-latitude circulation systems as a likely explanation for the northern Vietnam record. We explore the correspondence between our record and other proxy data from Southeast Asia and suggest possible implications of the differences between Vietnamese and Chinese speleothem records during the Little Ice Age. References cited: Liu Z., Wen X., Brady E. C., Otto-Bliesner B., Yu G., Lu H., Cheng H., Wang Y., Zheng W., Ding Y., Edwards R. L., Cheng J., Liu W. and Yang H. (2014) Chinese cave records and the East Asia Summer Monsoon. Quaternary Science Reviews 83, 115-128.

  8. A Study on Expression and Tyrosine 705 phosphorylation of STAT3 ...

    African Journals Online (AJOL)

    Fas- and Bcl-2-positive cells counts on the one hand, and apoptosis-positive nerve cells count in IP and. IC, on the ..... Chen Z, Li L, Mo X, Zhang L, Xie Y, Guo Q, Wang Y. Non-invasive ... Du W, Hong J, Wang YC, Zhang YJ, Wang P, Su YW,. Lin YW, Lu R, ... Jo M, Park MH, Kollipara PS, An BJ, Song HS, Han SB,. Kim JH ...

  9. GAO Performance and Accountability Report 2001

    National Research Council Canada - National Science Library

    2001-01-01

    The U.S. General Accounting Office is an independent, professional, nonpartisan agency in the legislative branch that is commonly called the investigative arm of the Congress or the Congress's "watchdog...

  10. Hybrid Chaos Synchronization of Four-Scroll Systems via Active Control

    Science.gov (United States)

    Karthikeyan, Rajagopal; Sundarapandian, Vaidyanathan

    2014-03-01

    This paper investigates the hybrid chaos synchronization of identical Wang four-scroll systems (Wang, 2009), identical Liu-Chen four-scroll systems (Liu and Chen, 2004) and non-identical Wang and Liu-Chen four-scroll systems. Active control method is the method adopted to achieve the hybrid chaos synchronization of the four-scroll chaotic systems addressed in this paper and our synchronization results are established using Lyapunov stability theory. Since the Lyapunov exponents are not required for these calculations, the active control method is effective and convenient to hybrid synchronize identical and different Wang and Liu-Chen four-scroll chaotic systems. Numerical simulations are also shown to illustrate and validate the hybrid synchronization results derived in this paper.

  11. New Jurassic tettigarctid cicadas from China with a novel example of disruptive coloration

    Directory of Open Access Journals (Sweden)

    Jun Chen

    2016-12-01

    Full Text Available Tettigarctidae is the most primitive family of Cicadoidea, with only two relict species. Although they are relatively well known from Eurasia, Australia, Africa, and South America, their Mesozoic examples are typically preserved only as isolated forewings. Herein, a new genus Sanmai Chen, Zhang, and B. Wang with three new species (Sanmai kongi Chen, Zhang, and B. Wang, S. mengi Chen, Zhang, and B. Wang, and S. xuni Chen, Zhang, and B. Wang are described based on fossil specimens from the Middle–Upper Jurassic of northeastern China, with well-preserved body structures, forewing and hindwing venations, making it the hitherto best known extinct tettigarctid taxon. The new genus, provisionally assigned to the tribe Turutanoviini, provides some new information about the evolution and palaeobiogeography of Mesozoic Tettigarctidae. The genus Paraprosbole is synonymized with Shuraboprosbole. In addition, the coloration pattern of forewing, prominent on some specimens of Sanmai kongi Chen, Zhang, and B. Wang sp. nov. and Sanmai xuni Chen, Zhang, and B. Wang sp. nov., represents a novel example of disruptive coloration in Tettigarctidae, which can effectively break up the body outline as well as surface, and so likely enabled these cicadas to reduce the detectability of potential predators.

  12. RASSF1A hypermethylation is associated with ASXL1 mutation and indicates an adverse outcome in non-M3 acute myeloid leukemia

    Directory of Open Access Journals (Sweden)

    Liu F

    2017-08-01

    Full Text Available Fang Liu,1,* Ming Gong,2,* Li Gao,2,* Xiaoping Cai,3 Hui Zhang,2 Yigai Ma2 1Department of Oncology, Chinese PLA General Hospital, 2Department of Hematology, China-Japan Friendship Hospital, 3Department of Geriatric Medicine, Army General Hospital, Beijing, People’s Republic of China *These authors contributed equally to this work Objective: The purpose of this study was to evaluate the frequency of RASSF1A hypermethylation in patients with acute myeloid leukemia (AML, in an attempt to modify the current molecular model for disease prognosis.Materials and methods: Aberrant RASSF1A promoter methylation levels were assessed in 226 newly diagnosed non-M3 AML patients and 30 apparently healthy controls, by quantitative methylation-specific polymerase chain reaction. Meanwhile, RASSF1A mRNA levels were detected by real-time quantitative polymerase chain reaction. Furthermore, hematological characteristics, cytogenetic abnormalities, and genetic aberrations were assessed. Finally, associations of RASSF1A hypermethylation with clinical outcomes were evaluated.Results: RASSF1A hypermethylation was observed in 23.0% of patients with non-M3 AML (52/226, but not in controls. Meanwhile, hypermethylation of the RASSF1A promoter was significantly associated with ASXL1 mutation. Furthermore, the log-rank test revealed that RASSF1A hypermethylation indicated decreased relapse-free survival (RFS and overall survival (OS in patients with non-M3 AML (P=0.012 and P=0.014, respectively. In multivariate analysis, RASSF1A hypermethylation was an independent prognostic factor for RFS (P=0.040, but not for OS (P=0.060.Conclusion: Hypermethylation of the RASSF1A promoter is associated with ASXL1 mutation in non-M3 AML patients, likely indicating poor outcome. These findings provide a molecular basis for stratified diagnosis and prognostic evaluation. Keywords: RASSF1A, hypermethylation, acute myeloid leukemia, clinical outcome, survival

  13. Experiment list: SRX1090864 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ming || cell type=intermediate stage of somatic cell reprogramming || chip antibody...5,12.8,491 GSM1816301: pre-iPS rep.H3.MNase-ChIP-Seq; Mus musculus; ChIP-Seq source_name=intermediate stage of somatic cell reprogram

  14. Oscillating solitons in nonlinear optics

    Indian Academy of Sciences (India)

    Author Affiliations. Lin Xiao-Gang1 Liu Wen-Jun2 Lei Ming2. Key Laboratory of Optoelectronic Technology & Systems (Chongqing University), Ministry of Education, Chongqing, China; School of Science, Beijing University of Posts and Telecommunications, P.O. Box 122, Beijing 100876, China ...

  15. DNA damage and decrease of cellular oxidase activity in piglet ...

    African Journals Online (AJOL)

    DNA damage and decrease of cellular oxidase activity in piglet sertoli cells exposed to gossypol. Ming Zhang, Hui Yuan, Zuping He, Liyun Yuan, Jine Yi, Sijun Deng, Li Zhu, Chengzhi Guo, Yin Lu, Jing Wu, Lixin Wen, Qiang Wei, Liqun Xue ...

  16. [Study of changes in Chinese herbal medicine distribution channel].

    Science.gov (United States)

    Lv, Hua; Yang, Guang; Huang, Lu-Qi

    2014-07-01

    Distribution channel of Chinese herbal medicines has been changing. From Han to Ming Dynasty, Chinese herbal medicine were mainly trafficked to urban by dealers or farmers; From the Ming Dynasty to the foundation of new China, distribution channels are primarily intermediated with township "bazaar" and national distribution center with fixed place and regularly trading hours. In the planned economy period, the state-owned herbal medicine company was the sole medium with monopoly nature. From the mid1980s to the end of last century, planned economy and market economy have been co-existing. Stepping into 21st century, producing area highlighted in the distribution channels. Presence or absence and rise or fall of different types of distribution market went throughout the changing process of distribution channels, which became an important clue. Changes were motivated by economical consideration of channel subject, which originated from commodity characteristic and social environment changes.

  17. Cone-beam computed tomography study of the root and canal morphology of mandibular permanent anterior teeth in a Chongqing population [Corrigendum

    Directory of Open Access Journals (Sweden)

    Yang ZY

    2016-03-01

    Full Text Available Zhengyan Yang, Keke Lu, Fei Wang, Yueheng Li, Zhi ZhouDepartment of Preventive Dentistry, The College of Stomatology, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, People’s Republic of ChinaOn page 19, the author’s names were listed incorrectly as Yang Zhengyan, Lu Keke, Wang Fei, Li Yueheng, Zhou Zhi.The correct names are Zhengyan Yang, Keke Lu, Fei Wang, Yueheng Li, Zhi Zhou.View the original paper here.

  18. Consumer evaluation of imported organic food products in emerging economies in Asia

    OpenAIRE

    Pedersen, Susanne; Aschemann-Witzel, Jessica; Thøgersen, John

    2017-01-01

    Consumer evaluation of imported organic food products in emerging economies in Asia Introduction Consumers in emerging economies such as Thailand and China have started to demand organic food products – mainly due to food safety reasons (Ortega, Wang, Wu, & Hong, 2015; Roitner-Schobesberger, Darnhofer, Somsook, & Vogl, 2008; C. L. Wang, Li, Barnes, & Ahn, 2012; O. Wang, De Steur, Gellynck, & Verbeke, 2015). However, since the domestic organic markets are still not well-establi...

  19. Correlation of primary tumor FDG uptake with histopathologic features of advanced gastric cancer

    International Nuclear Information System (INIS)

    Kim, Hae Won; Won, Kyoung Sook; Song, Bong Il; Kang, Yu Na

    2015-01-01

    Histopathologic features could affect the FDG uptake of primary gastric cancer and detection rate on FDG PET/CT. The aim of this study was to evaluate the FDG uptake of primary gastric cancer by correlating it with the histopathologic features of the tumors. Fifty patients with locally advanced gastric adenocarcinoma who were referred for preoperative FDG-PET/CT scans were enrolled in this study. The detection rate of PET/CT and maximum standardized uptake values (SUV max ) of the primary tumor were compared using the WHO, Lauren, Ming and Borrmann classifications and tumor size and location. In 45 of the 50 patients (90 %), the primary gastric tumors were detected by FDG PET/CT. On comparison using the WHO classification, the detection rate and SUV max of the tubular type were significantly higher than those of the poorly cohesive type. On comparison using the Lauren and Ming classifications, the SUV maxs of the intestinal type and expanding type were significantly higher than those of the diffuse and infiltrative type, respectively. On comparison using the Borrmann classification and tumor size and location, there was no significant difference in the detection rate and SUV max of primary gastric tumors. This study demonstrates that the poorly cohesive type according to the WHO classification, diffuse type according to the Lauren classification and infiltrative type according to the Ming classification have low FDG uptake in patients with locally advanced gastric carcinoma. Understanding the relationship between primary tumor FDG uptake and histopathologic features would be helpful in detecting the primary tumor by FDG PET/CT in patients with gastric cancer

  20. A new approximate algorithm for image reconstruction in cone-beam spiral CT at small cone-angles

    International Nuclear Information System (INIS)

    Schaller, S.; Flohr, T.; Steffen, P.

    1996-01-01

    This paper presents a new approximate algorithm for image reconstruction with cone-beam spiral CT data at relatively small cone-angles. Based on the algorithm of Wang et al., our method combines a special complementary interpolation with filtered backprojection. The presented algorithm has three main advantages over Wang's algorithm: (1) It overcomes the pitch limitation of Wang's algorithm. (2) It significantly improves z-resolution when suitable sampling schemes are applied. (3) It avoids the waste of applied radiation dose inherent to Wang's algorithm. Usage of the total applied dose is an important requirement in medical imaging. Our method has been implemented on a standard workstation. Reconstructions of computer-simulated data of different phantoms, assuming sampling conditions and image quality requirements typical to medical CT, show encouraging results

  1. Polymeric implant of methylprednisolone for spinal injury ...

    African Journals Online (AJOL)

    Polymeric implant of methylprednisolone for spinal injury: preparation and characterization. Bo Yin, Jian-Jun Ji, Ming Yang. Abstract. Purpose: To improve the effectiveness and reduce the systemic side effects of methylprednisolone in traumatic spinal injuries, its polymeric implants were prepared using chitosan and sodium ...

  2. Preparation and characterization of LaNiO3 films grown by metal ...

    Indian Academy of Sciences (India)

    Administrator

    Keywords. Conductive films; LaNiO3; metal–organic deposition; texture. 1. Introduction ... films on Si (111) and quartz substrates were first prepared with the 2-ethyl hexanotes of ..... Li A, Ge C, Lü P and Ming N 1996a Appl. Phys. Lett. 68. 1347.

  3. A Self-Adaptive Energy-Efficient Framework for Large Unattended Wireless Sensor Networks

    Science.gov (United States)

    2014-11-06

    Transactions on Vehicular Technology, (10 2011): 3919. doi: 10.1109/ TVT .2011.2166093 Miao Zhao, Yuanyuan Yang. Optimization-Based DistributedAlgorithms for...Networks, IEEE Transactions on Vehicular Technology, (05 2013): 0. doi: 10.1109/ TVT .2012.2229309 Miao Zhao, Ming Ma, Yuanyuan Yang. Applying

  4. Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor

    OpenAIRE

    Wang,Guang-Yu; Li,Ling; Liu,Bo; Han,Xiao; Wang,Chunhua; Wang,Jiwen

    2018-01-01

    Guang-Yu Wang,1,* Ling Li,2,* Bo Liu,1 Xiao Han,1 Chun-Hua Wang,1 Ji-Wen Wang3 1Department of Neurosurgery, 2Department of Pediatrics, Qilu Children’s Hospital of Shandong University, Jinan, Shandong, 3Department of Neurology, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Pudong New District, Shanghai, People’s Republic of China *These authors contributed equally to this work Purpose: This study aimed to explore ...

  5. Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor

    OpenAIRE

    Wang G; Li L; Liu B; Han X; Wang CH; Wang JW

    2018-01-01

    Guang-Yu Wang,1,* Ling Li,2,* Bo Liu,1 Xiao Han,1 Chun-Hua Wang,1 Ji-Wen Wang3 1Department of Neurosurgery, 2Department of Pediatrics, Qilu Children’s Hospital of Shandong University, Jinan, Shandong, 3Department of Neurology, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Pudong New District, Shanghai, People’s Republic of China *These authors contributed equally to this work Purpose: This study aimed to explore significant gene...

  6. Reforming China’s Criminal Procedure Law

    OpenAIRE

    Winckler, Hugo

    2014-01-01

    Sources:- Wang Jianxun, “The provisions of the reform of criminal procedural law legalising secret investigations are a step backwards,” Caijing wang, 5 September 2011.- Chen Youxi, “The legalisation of secret investigations is an important violation of political integrity,” Zhongguo wangluo dianshitai – CNTV web site, Opinion section, 27 November 2011.- Wu Zhehua, “Chen Weidong discusses reform of the criminal procedure law: Behind each article there is a story,” Zhongguoguangbo wang, 8 Marc...

  7. DOE management

    International Nuclear Information System (INIS)

    Rezendes, V.S.

    1991-07-01

    This paper reports that GAO, as well as the Department of Energy's Inspector General, have pointed out the need for major improvement in the University of California's management of the three DOE laboratories-Lawrence Livermore, Los Alamos, and Lawrence Berkeley- and DOE oversight of that management effort. GAO found problems with University of California controls over laboratory operations, such as managing property, protecting classified documents, and ensuring that subcontractors are not subject to foreign influence, which might lead to transfers of nuclear technology to foreign influence, which might lead to transfers of nuclear technology or materials to foreign countries. In addition, clauses in the University of California contracts hamper DOE's ability to effectively manage the laboratories. DOE has addressed many of the specific problems that GAO identified and has tried to improve overall contract management. Negotiations with the University of California to extend the laboratory contracts will present another opportunity for DOE to take a firm stance on the need for management improvements. Having appropriate procedures and resources in place would also help DOE carry out its administration of contracts

  8. Cleaning up commingled uranium mill tailings: is Federal assistance necessary

    International Nuclear Information System (INIS)

    1979-01-01

    GAO was asked to determine whether Federal assistance should be given to operating mill owners that have processed uranium for sale to both government and industry and, thus, generated residual radioactive wastes. The wastes generated for both government and commercial use are called commingled uranium mill tailings. GAO recommends that the Congress provide assistance to active mill owners to share in the cost of cleaning up that portion of the tailings which were produced under Federal contract. Further, GAO believes that the Congress should also consider having the Federal government assist those mills who acted in good faith in meeting all legal requirements pertaining to controlling the mill tailings that were generated for commercial purposes and for which the Federal government is now requiring retroactive remedial action. At the same time, the Congress should make sure that this action establishes no precedent for the Federal government assuming the financial responsibility of cleaning up other non-Federal nuclear facilities and wastes, including those mill tailings generated after the date when the Federal government notified industry that the failings should be controlled

  9. Wide Band Gap Semiconductors Symposium Held in Boston, Massachusetts on 2-6 December 1991. Materials Research Society Symposium Proceedings. Volume 242

    Science.gov (United States)

    1992-01-01

    AND PROPERTIES OF WIDE BAND-GAP Il-VI STRAINED- LAYER SUPERLATTICE 227 Hailong Wang. Jie Cui. Aidong Shen. Liang Xu, Yunliang Chen. and Yuhua Shen IN...WANG JIE CUI AIDONG SHEN LIANG XU YUNLIANG CHEN AND YUHUA SHEN Shanghai Institute of Optics and Fine Mechanics, Academia Sinica P.O.Box 800-216 Shanghai...He Zujou, Cao Huazhe, Su Wuda, Chen Zhongcai, Zhon Feng and Wang Erguang, Thin Solid Films, 139,261(1986). 22) Xin Li and T.L.Tansley, J.AppI.Phys

  10. The Role of Retinal Determination Gene Network (RDGN) in Hormone Signaling Transduction and Prostate Tumorigenes

    Science.gov (United States)

    2015-12-01

    S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, Wang C, McMahon SB, Pestell RG...MP, Wang C, Pestell RG. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. Oncotarget...MP, Quong A, Ertel A, Pestell RG. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Res. 2014;74(3):829

  11. ADP Regulates the Structure and Function of the Protein KaiC

    Science.gov (United States)

    2016-08-11

    LiWang lab exploited this in vitro clock system to gain an atomic -resolution understanding of a circadian clock. The rationale is that fundamental...researchers are Hispanic. On a peer-reviewed research article from the LiWang lab, a Hispanic undergraduate student was an author, as were two non...Using both NMR and fluorescence spectroscopy , the LiWang lab showed that KaiA enhances KaiB-KaiC binding, and KaiC enhances KaiA-KaiB binding (Tseng et

  12. Performing "Chinese-ness" in Singkawang

    NARCIS (Netherlands)

    Ong, C.E.; Ormond, M.E.; Sulianti, Dian

    2017-01-01

    Through an examination of two festivals – Qing Ming and Cap Go Meh – in the town of Singkawang in Indonesian Borneo (Kalimantan), we show how Singkawang-bound Chinese Indonesian tourists and their Singkawang-based relatives produce a diasporic heritage network through ‘moorings’ generated by both

  13. A generalized solution for groundwater head fluctuation in a tidal ...

    Indian Academy of Sciences (India)

    Mo-Hsiung Chuang1 and Hund-Der Yeh2,∗. 1Department of Urban Planning and Disaster Management, Ming-Chuan University,. Gweishan District, Taoyuan, Taiwan. 2Institute of Environmental Engineering, National Chiao Tung University, Hsinchu, Taiwan. ∗. Corresponding author. e-mail: hdyeh@mail.nctu.edu.tw.

  14. Broad-Band Spectral Indices Variability of BL Lacertae by Wavelet ...

    Indian Academy of Sciences (India)

    by Wavelet Method. Hao-Jing Zhang1,2,∗, Jing-Ming Bai1, Yu-Ying Bao3 & Xiong Zhang2. 1Yunnan Astronomical Observatory, National Astronomical Observatory, ... 3Department of Physics, Yuxi Teachers' College, Yuxi, Yunnan 653100, China. ∗ ... broad-band spectral indices—periodic variation—methods: numerical:.

  15. A Review of Research on Problematic Internet Use and Well-Being: With Recommendations for the U.S. Air Force

    Science.gov (United States)

    2015-01-01

    ADHD attention deficit hyperactivity disorder ...Yueh Wu, and Ming-Jen Yang, “The Comorbid Psychiatric Symptoms of Internet Addiction: Attention Deficit and Hyperactivity 42 Disorder ( ADHD ... disorder or combination of disorders , such as major depression or attention deficit hyperactivity disorder . The evidence is quite strong that people

  16. Landform affects on profile distribution of soil properties in black locust

    African Journals Online (AJOL)

    STORAGESEVER

    2009-07-06

    Jul 6, 2009 ... Wei Xiao-rong1, Shao Ming-an1*, Zhang Xing-chang1 and Shao Hong-bo1,2,3*. 1State Key Laboratory of Soil ... temperature regime, plant structure and erosion and sedi- .... The soil in the area is fine silt in texture and.

  17. Kinoonud esitlevad unenäolist kogumikku

    Index Scriptorium Estoniae

    2008-01-01

    Tartus Athena keskuses esitletakse täna 10 filmikatkest koosnevat DVD-kogumikku "Akadeemik Obruchevi unenägu" (produtsent Urmas Reisberg, režissöörid Martin Liira, Urmas Nimetu ja Richard Meitern), mille aluseks on Andres Ehini luuletus "Dr. Lü-Ming ja Saatus", tootjaks Kinoonud

  18. Silk, porcelain and lacquer : China and Japan and their trade with Western Europe and the New World, 1500-1644. A survey of documentary and material evidence

    NARCIS (Netherlands)

    Llorens Planella, Maria Teresa (Teresa Canepa)

    2015-01-01

    This dissertation focused on the prolific early European trade and consumption of three Asian manufactured goods: Chinese silk and porcelain, and Japanese lacquer in the sixteenth and early seventeenth centuries, and has shown how the material cultures of late Ming China and Momoyama/early Edo Japan

  19. Risk of spacecraft on-orbit obsolescence: Novel framework, stochastic modeling, and implications

    Science.gov (United States)

    Dubos, Gregory F.; Saleh, Joseph H.

    2010-07-01

    The Government Accountability Office (GAO) has repeatedly noted the difficulties encountered by the Department of Defense (DOD) in keeping its acquisition of space systems on schedule and within budget. Among the recommendations provided by GAO, a minimum Technology Readiness Level (TRL) for technologies to be included in the development of a space system is advised. The DOD considers this recommendation impractical arguing that if space systems were designed with only mature technologies (high TRL), they would likely become obsolete on-orbit fairly quickly. The risk of on-orbit obsolescence is a key argument in the DOD's position for dipping into low technology maturity for space acquisition programs, but this policy unfortunately often results in the cost growth and schedule slippage criticized by the GAO. The concept of risk of on-orbit obsolescence has remained qualitative to date. In this paper, we formulate a theory of risk of on-orbit obsolescence by building on the traditional notion of obsolescence and adapting it to the specificities of space systems. We develop a stochastic model for quantifying and analyzing the risk of on-orbit obsolescence, and we assess, in its light, the appropriateness of DOD's rationale for maintaining low TRL technologies in its acquisition of space assets as a strategy for mitigating on-orbit obsolescence. Our model and results contribute one step towards the resolution of the conceptual stalemate on this matter between the DOD and the GAO, and we hope will inspire academics to further investigate the risk of on-orbit obsolescence.

  20. Study on sources of colored glaze of Xiyue Temple in Shanxi province by INAA and multivariable statistical analysis

    International Nuclear Information System (INIS)

    Cheng Lin; Feng Songlin

    2005-01-01

    The major, minor and trace elements in the bodies of ancient colored glazes which came from the site of Xiyue Temple and Lidipo kiln in Shanxi province, and were unearthed from the stratums of Song, Yuan, Ming, Early Qing and Late Qing dynasty were analyzed by instrumental neutron activation analysis (INAA). The results of multivariable statistical analyses show that the chemical compositions of the colored glaze bodies are steady from Song to Early Qing dynasty, but distinctly different from that in Late Qing. Probably, the sources of fired material of ancient colored glaze from Song to Early Qing came from the site of Xiyue Temple. The chemical compositions of three pieces of colored glazes in Ming dynasty and that in Late Qing are similar to that of Lidipo kiln. From this, authors could conclude that the sources of the materials of ancient coloured glazes of Xiyue Temple in Late Qing dynasty were fired in Lidipo kiln. (authors)