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Sample records for fredrik miegel tobias

  1. Tuppiap Qeqertaa (Tobias Island): a newly discovered island off northeast Greenland

    DEFF Research Database (Denmark)

    Bennike, O.; Mikkelsen, N.; Forsberg, René

    2006-01-01

    The small island of Tuppiap Qeqertaa, formerly known as Tobias circle divide or Tobias Island, is situated 80 km off the northeast Greenland coast. The island was discovered in 1993 and is approximately 2 km long and 1.5 km wide. Most of the island is covered by an ice cap that rises to 35 in abo...

  2. Tobias, Rudolf: Jonah's Mission / Warrack, John

    Index Scriptorium Estoniae

    Warrack, John

    1996-01-01

    Uuest heliplaadist "Tobias, Rudolf: Jonah's Mission. Pille Lill (sop), Urve Tauts (mez), Peter Svensson (ten), Raimo Laukka (bar), Mati Palm (bass); Tallinn Boys' Choir, Estonian Philharmonic Chamber Choir, Oratorio Choir, Estonian State Symphony Orchestra, Neeme Järvi" BIS CD 731/2 (two discs: 114 minutes: DDD)

  3. Tobias, Rudolf: Des Jona Sendung / Olivier Opdebeeck

    Index Scriptorium Estoniae

    Opdebeeck, Olivier

    1996-01-01

    Uuest heliplaadist "Tobias, Rudolf: Des Jona Sendung. Pille Lill (soprano), Urve Tauts (mezzo-soprano), Peter Svensson (tenor), Raimo Laukka (baryton), Mati Palm (basse); Choeur d'Oratorio, Choeur de chambre Philharmonique d'Estonie, Choeur de garcons de Tallinn, Orchestre Symphonique d'Etat d'Estonie, Neeme Järvi" BIS CD-731/732, distribution Arcade 8000 716 (2 CD: 290F). TT: 1h 54'13"

  4. Q & A with Ed Tech Leaders: Interview with Sigmund Tobias

    Science.gov (United States)

    Shaughnessy, Michael F.; Fulgham, Susan M.

    2016-01-01

    Sigmund Tobias came to the United States in 1948, after his family had fled to China from the Holocaust in Europe. His Memoir ("Strange Haven: A Jewish Childhood in Wartime Shanghai") describes that part of his life. He settled in New York, where he completed his B.A. and M.S. in School Psychology from the City College of New York, and a…

  5. Thomas Mann's "Tobias Mindernickel" in Light of Sartre's "Being-for-Others"

    Directory of Open Access Journals (Sweden)

    Beth Bjorklund

    1978-01-01

    Full Text Available Sartre's analysis of "Being-for-Others" in Being and Nothingness describes the Self-Other relationship as essentially one of conflict, with the Self attempting either to dominate or to be dominated by the Other. Subject-Object relations are a common theme also in the early works of Thomas Mann, who gives artistic expression to many of the same problems which Sartre later formalized in a philosophical theory. The sado-masochistic character, which is portrayed in several of Thomas Mann's narratives, receives its strongest expression in the story "Tobias Mindernickel," which is here singled out for analysis. Humiliation gives rise to aggression, as the protagonist feels both an attraction and a repulsion for his surrogate lover, a dog. The interpersonal relationships revealed here serve as paradigmatic illustration of Sartre's theory of "Concrete Relations with Others."

  6. Human radiation studies: Remembering the early years. Oral history of biophysicist Cornelius A. Tobias, Ph.D., January 16, 1995

    International Nuclear Information System (INIS)

    1995-07-01

    Dr. Cornelius A. Tobias was interviewed by representatives of US DOE Office of Human Radiation Experiments (OHRE). He was chosen for this interview because of his extensive biophysics and medical physics research activities while he was employed by the University of California, Berkeley and San Francisco and at the Donner Laboratory. He discusses his involvement in wartime studies of effects of high altitude on aviators, carbon monoxide with radioactive tracers, blood studies with radioactive iron, human use committees, heavy-ion research with the Bevatron, boron isotope research, classified research involving human subjects, heavy-particle radiography, heavy- particle beams and medical research, and pituitary irradiation studies,

  7. Human radiation studies: Remembering the early years. Oral history of biophysicist Cornelius A. Tobias, Ph.D., January 16, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    Dr. Cornelius A. Tobias was interviewed by representatives of US DOE Office of Human Radiation Experiments (OHRE). He was chosen for this interview because of his extensive biophysics and medical physics research activities while he was employed by the University of California, Berkeley and San Francisco and at the Donner Laboratory. He discusses his involvement in wartime studies of effects of high altitude on aviators, carbon monoxide with radioactive tracers, blood studies with radioactive iron, human use committees, heavy-ion research with the Bevatron, boron isotope research, classified research involving human subjects, heavy-particle radiography, heavy- particle beams and medical research, and pituitary irradiation studies,.

  8. Fatores Desarticuladores da Cooperação em Arranjos Produtivos Locais: Um Estudo Quantitativo no APL de Confecções de Tobias Barreto/SE

    Directory of Open Access Journals (Sweden)

    Abimael Magno Do Ouro Filho

    2015-01-01

    Full Text Available Em decorrência do ambiente competitivo e das suas limitações, as micro e pequenas empresas (MPE ́s têm procurado soluções por meio de novas formas de organização como os APLs (Arranjos Produtivos Locais. A maior parte da literatura sobre APL aponta para os fatores motivadores na criação desses arranjos. Entretanto poucos estudos focalizam os fatores que dificultam a cooperação neste tipo de rede. Sob essa perspectiva, o objetivo deste artigo é identificar quais os fatores que influenciam na desarticulaçãoentre os atores do APL de confecções em Tobias Barreto/SE. A pesquisa utilizou o método quantitativo, e foram aplicados 224 questionários a micro e pequenas empresas participantes do APL de Tobias Barreto. Na análise dos dados, foi utilizado o teste de Mann-Whitney para teste de hipóteses, e a regressão logística univariada. Os resultados da pesquisa demonstram que o número de participantes, a falta de confiança entre eles, os conflitos e o aparecimento do comportamento oportunista são fatores que contribuem para a desarticulação entre os atores dos arranjos produtivos locais.

  9. The Early Planetary Research of Tobias C. Owen

    Science.gov (United States)

    Cruikshank, Dale P.

    2017-10-01

    Tobias Chant Owen (Toby) was a graduate student of G. P. Kuiper, receiving his Ph.D. in the Dept. of Astronomy, University of Arizona, in 1965. His thesis was broadly titled "Studies of Planetary Spectra in the Photographic Infrared", and primarily presented a study of the composition and other properties of Jupiter, as well as the abundance and surface pressure of CO2 on Mars. The surface pressure on Mars was a topic of debate at that time, with a wide range of diverse observational results from several investigators. The Jupiter work in particular consisted of the analysis of Kuiper's unpublished spectra that were made with photographic plates pushed to the longest wavelength possible, about 1120 nm, with ammonia-hypersensitized Kodak Z emulsions. Toby used the long-pathlength absorption cells at the Lunar and Planetary Lab to study the spectra of CH4 and NH3 at pressures and temperatures relevant to Jupiter (and Saturn), as well as to search for spectral signatures of potential minor components of their atmospheres. Toby also obtained new spectra of Io, Ganymede, and Saturn and its rings, extended to the long-wavelength limit of photographic emulsions. No new molecular absorptions were found, although Owen basically confirmed Kuiper's earlier result that Saturn's rings are covered (or composed of) with H2O ice or frost. As he pursued a broad range of problems of planetary atmospheres, Toby used existing and newly acquired spectra of the planets in the photographic and near-infrared wavelength regions, together with data he obtained in the laboratory with long-pathlength absorption cells, to resolve some outstanding issues of unidentified spectral features and to clarify issues of the compositions, temperatures, and atmospheric pressures of several bodies. This work laid the foundation for his later decades of studies of planetary atmospheres and comets with spacecraft as an active participant in many US and European missions. He was very influential in shaping

  10. The polychrome works “Prayer of Tobias and Sarah” and “The Archangel Raphael reveals himself to Tobi and his son Tobias”, inside the Cathedral of Cosenza: diagnostic investigations and considerations on the conditions of conservation

    Directory of Open Access Journals (Sweden)

    Gianluca Nava

    2008-04-01

    Full Text Available The oil paintings and “Prayer of Tobias and Sarah” and “The Archangel Raphael reveals himself to Tobi and his son Tobias”, executed by Francesco Bruno at the end of the XVIII century on oval Conservation Science in Cultural Heritage 210 shaped canvas, were investigated by integrated physica-chemical and analytical methodologies in order to obtain scientific data capable of elucidating the state of conservation and the painting technique. Optical (OM and electronic (SEM-EDS microscopy, micro-FT-IR spectroscopy, were applied on some microfragments whilst the two whole paintings were analyzed by the non invasive IR reflectografy technique. The reflectography evidenced some pentimenti of author on the canvas “Prayer of Tobias and Sarah”, while invasive analysis made it possible to locate the stratigraphic sequence of each canvas and to characterise the constituent materials.

  11. 2011 International Infantry and Joint Services Small Arms Systems Symposium, Exhibition and Firing Demonstration

    Science.gov (United States)

    2011-05-26

    Kinetics Tungsten Carbide Material Research and Development of Small Arms Ammunition Armour Piercing, Mr. Fredrik Eringe, Nammo Talley 12818 - Tracer...Ammunition Armour Piercing Mr. Fredrik Eringe, Nammo Talley SMALL ARMS SYSTEMS AGENDA: 05/25/11 2:40 pm - 3:10 pm BREAK - EXHIBIT HALL 3:10 pm - 4:50...inroads within the academic community by way of word-of-mouth advertisement at the faculty and the student level  Ability to sponsor needed research

  12. Review of the East Palaearctic and North Oriental Psyttalia Walker, with the description of three new species (Hymenoptera, Braconidae, Opiinae).

    Science.gov (United States)

    Wu, Qiong; van Achterberg, Cornelis; Tan, Jiang-Li; Chen, Xue-Xin

    2016-01-01

    The East Palaearctic and North Oriental species of the genus Psyttalia Walker (Hymenoptera, Braconidae, Opiinae) are reviewed. Three new species are described and illustrated: Psyttalia latinervis Wu & van Achterberg, sp. n . and Psyttalia majocellata Wu & van Achterberg, sp. n . from China, and Psyttalia spectabilis van Achterberg, sp. n. from Japan. Coeloreuteus formosanus Watanabe, 1934, Opius (Lissosema) proclivis Papp, 1981, Opius (Psyttalia) subcyclogaster Tobias, 1998, Opius (Psyttalia) darasunicus Tobias, 1998, Opius (Psyttalia) cyclogastroides Tobias, 1998, Psyttalia extensa Weng & Chen, 2001, and Rhogadopsis longicaudifera Li & van Achterberg, 2013, are new synonyms of Psyttalia cyclogaster (Thomson, 1895); Opius (Psyttalia) ophthalmicus Tobias, 1977, and Opius (Psyttalia) brevitemporalis Tobias, 1998, of Psyttalia carinata (Thomson, 1895) and both Opius (Psyttalia) vacuus Tobias, 1998, and Opius (Lissosema) longurius Chen & Weng, 1995, of Rhogadopsis mediocarinata (Fischer, 1963). Phaedrotoma daghestanicum (Telenga, 1950), Rhogadopsis mediocarinata (Fischer, 1963) and Rhogadopsis mystica (Fischer, 1963) are new combinations. New records are Psyttalia carinata (Thomson, 1895) from The Netherlands and Norway, and Psyttalia cyclogaster (Thomson, 1895) from Japan. A lectotype is designated for Psyttalia carinata (Thomson, 1895) and Psyttalia cyclogaster (Thomson, 1895). A key to the East Palaearctic and North Oriental species of the genus Psyttalia Walker is included.

  13. Review of the East Palaearctic and North Oriental Psyttalia Walker, with the description of three new species (Hymenoptera, Braconidae, Opiinae

    Directory of Open Access Journals (Sweden)

    Qiong Wu

    2016-11-01

    Full Text Available The East Palaearctic and North Oriental species of the genus Psyttalia Walker (Hymenoptera, Braconidae, Opiinae are reviewed. Three new species are described and illustrated: P. latinervis Wu & van Achterberg, sp. n. and P. majocellata Wu & van Achterberg, sp. n. from China, and P. spectabilis van Achterberg, sp. n. from Japan. Coeloreuteus formosanus Watanabe, 1934, Opius (Lissosema proclivis Papp, 1981, O. (Psyttalia subcyclogaster Tobias, 1998, O. (P. darasunicus Tobias, 1998, O. (P. cyclogastroides Tobias, 1998, Psyttalia extensa Weng & Chen, 2001, and Rhogadopsis longicaudifera Li & van Achterberg, 2013, are new synonyms of Psyttalia cyclogaster (Thomson, 1895; Opius (Psyttalia ophthalmicus Tobias, 1977, and O. (P. brevitemporalis Tobias, 1998, of Psyttalia carinata (Thomson, 1895 and both O. (P. vacuus Tobias, 1998, and O. (Lissosema longurius Chen & Weng, 1995, of Rhogadopsis mediocarinata (Fischer, 1963. Phaedrotoma daghestanicum (Telenga, 1950, Rhogadopsis mediocarinata (Fischer, 1963 and R. mystica (Fischer, 1963 are new combinations. New records are Psyttalia carinata (Thomson, 1895 from The Netherlands and Norway, and P. cyclogaster (Thomson, 1895 from Japan. A lectotype is designated for Psyttalia carinata (Thomson, 1895 and P. cyclogaster (Thomson, 1895. A key to the East Palaearctic and North Oriental species of the genus Psyttalia Walker is included.

  14. Muusikamaailm : Barenboimi festival Berliinis. Lihavõtteaegu Luzernis, Viinis, Salzburgis, Hamburgis ja Londonis. Soome ooper 150 / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2002-01-01

    Wagneri ooperite "Festtage" Berliinis. Lihavõtteaegu toimunud kontsertidest Luzernis, Viinis, Salzburgis, Hamburgis ja Londonis. Soome ooperiloo esimesest ooperist Fredrik Paciuse "Kuningas Karli jahiretk" sünnist on möödunud 150

  15. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Arne Jensen1 2. Graduate School of Mathematical Sciences, University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8914, Japan; Department of Mathematical Sciences, Aalborg University, Fredrik Bajers Vej 7G, DK-9220 Aalborg Ø, Denmark ...

  16. Name and shame in new regime / Fredrik Davidsson

    Index Scriptorium Estoniae

    Davidsson, Fredrik

    2010-01-01

    Euroopa Komisjon on algatanud kampaania, mille kohaselt peetakse internetis nimekirja laevandusettevõtetest, kes ei täida ohutusnõudeid. Euroopa Komisjoni transpordivolinik Siim Kallas uuest eeskirjast

  17. Synthetic tsunamis along the Israeli coast.

    Science.gov (United States)

    Tobias, Joshua; Stiassnie, Michael

    2012-04-13

    The new mathematical model for tsunami evolution by Tobias & Stiassnie (Tobias & Stiassnie 2011 J. Geophys. Res. Oceans 116, C06026) is used to derive a synthetic tsunami database for the southern part of the Eastern Mediterranean coast. Information about coastal tsunami amplitudes, half-periods, currents and inundation levels is presented.

  18. Gazprom prirutshil ministra / Sergei Tushin

    Index Scriptorium Estoniae

    Tushin, Sergei

    2006-01-01

    Peaminister Fredrik Reinfeldti juhitav uus Rootsi valitsus läheb ajalukku kui kõige ebastabiilsem valitsus Euroopas. Välisminister Carl Bildt on keerulises olukorras, kahtlustatakse, et tuntud poliitik ei suuda Moskvaga suheldes jäika joont pidada, kuna seoses naftaäriga omab majanduslikke huvisid Venemaal

  19. bouwen aan morgen met het bouwmateriaal van gisteren: tobit 7-8 ...

    African Journals Online (AJOL)

    He realises that it will only be possible to share a future together if the chaos of Sarah's past can be transformed, which begins when Tobias kills the voracious fish in the Tigris. River, a symbolic representation of destructive chaos. Once this has been defeated, Tobias is also able to triumph over Asmodeus, the demon ...

  20. Bouwen aan morgen met het bouwmateriaal van gisteren: Tobit 7-8 ...

    African Journals Online (AJOL)

    He realises that it will only be possible to share a future together if the chaos of Sarah's past can be transformed, which begins when Tobias kills the voracious fish in the Tigris River, a symbolic representation of destructive chaos. Once this has been defeated, Tobias is also able to triumph over Asmodeus, the demon ...

  1. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Arne Jensen1 Gheorghe Nenciu2 3. Department of Mathematical Sciences, Aalborg University, Fredrik Bajers Vej 7G, DK-9220 Aalborg Ø, Denmark; Department of Theoretical Physics, University of Bucharest, P. O. Box MG11, 76900 Bucharest, Romania; Institute of Mathematics “Simion Stoilow” of the Romanian Academy, ...

  2. The Prosimetrum: Orally Derived Literature?

    DEFF Research Database (Denmark)

    Walther, Sabine Heidi

    2009-01-01

    In: Agneta Ney, Henrik Williams und Fredrik Charpentier Ljungqvist (Hg.): Á austrvega. Saga and East Scandinavia. Preprint papers of The 14th International Saga Conference, Uppsala 9th - 15th August 2009. Gävle: University fo Gävle (Papers from the Department of Humanities and Social Sciences, 14...

  3. Echi omerici nel libro di Tobia ?

    Directory of Open Access Journals (Sweden)

    Toloni, Giancarlo

    2007-06-01

    Full Text Available The journey home to Nineveh by Tobiah recalls Odysseus’ novstoı to Ithaca, a journey marked by dangers and adventures and by the ideas of love and the family. The biblical book stands as a historical-religious novel although the origin is to be sought in the literary genre of folktalle enriched with didactic, edifying, and prophetic elements. This elementary narrative structure could go back to the Odyssey – archetype of the modern novel – and particularly to the folktale of Odysseus. The hagiographer could have thus re-written in theological perspective the ancient story of Tobit and Tobiah from biblical and parabiblical tradition so as to answer the problems of the Israel of his time. The numerous analogies concerning the themes (the journey to the East, the dangers, the family feelings, etc. and the narrative elements (the relation father-son, the dog,the intermediaries, the drug, etc. show that the author must have known Odysseus’ novstoı, and also that he relied on his readers’ knowledge of it when he outlined the story of Tobiah following the scheme of the Greek hero’s journey. One should speak of an intelligent attempt to exploit the fame of the Homeric tale in order to confer authoritative status to his story, rather than of literary dependence or emulation. Indeed, the author of the story of Tobiah uses the folktale of Odysseus to revive the hope of the Jewish community to return to their land, just like Tobiah returned to Nineveh from Rages happily married with Sarah.

    El viaje de vuelta a casa de Tobías evoca el novstoı de Odiseo a Ítaca marcado igualmente por peligros y aventuras y por asuntos de amor y familia. Este libro bíblico es una novela históricoreligiosa, pero, en su origen se encuentra el género literario de cuento popular, enriquecido con elementos didácticos, edificantes y proféticos. Esta estructura narrativa elemental podría remontarse a la Odisea –arquetipo de la novela moderna– y particularmente al cuento popular de Odiseo. El hagiógrafo, por tanto, pudo haber reelaborado con perspectiva teológica esta antigua historia de Tobit y Tobías, recogida de la tradición bíblica y parabíblica, para responder a los problemas del Israel de su tiempo. Las numerosas analogías entre los temas (el viaje de Oriente, los peligros, los sentimientos familiares… y los elementos narrativos (la relación padre-hijo, el perro, los intermediarios, la medicina… confirman que el autor debió de conocer el novstoı de Odiseo. Se basaba en el conocimiento que sus lectores tenían de él para delinear la historia de Tobías sobre el esquema de viaje del héroe griego. Más que de una dependencia literaria o de una emulación, se trata de un intento inteligente de explotar la fama del relato homérico para poner un sello autoritativo a su historia. En ese sentido, parte del relato popular de Odiseo para revivir las expectativas de la comunidad judía hacia una diáspora oriental, sometida e incierta sobre su destino, previendo la vuelta de la deportación como Tobías, que volvió a Nínive desde Rages, feliz de haberse casado con Sara.

  4. Metabolomics and Prostate Cancer

    Science.gov (United States)

    2013-05-01

    PRINCIPAL INVESTIGATOR: Fredrik Wiklund CONTRACTING ORGANIZATION: Karolinska Institutet, SE-171 77 Stockholm, Sweden REPORT DATE: May 2013...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) B and Biostatistics, Karolinska Institutet, P.O. Box 281, SE-171 77 Stockholm, Sweden AND ADDRESS(ES) 8...PERFORMING ORGANIZATION REPORT NUMBER Karolinska Institutet SE-171 77 Stockholm Sweden 9. SPONSORING / MONITORING AGENCY

  5. Creating a "Latino" Artist Identity in-between Sweden and Latin America - A Comparative Approach

    Directory of Open Access Journals (Sweden)

    Susan Lindholm

    2015-11-01

    Full Text Available This article engages in a close comparative reading of the creation of a “Latino” artist identity by two Swedish artists – Fredrik FreddeRico Ekelund and Rodrigo Rodde Bernal. By focusing on the theoretical concept of white Swedish masculin- ity, it aims to deepen the understanding of how such identities are created within and against the background of specific historical contexts and locations.

  6. Uute sõidukite jaemüüjate TOP

    Index Scriptorium Estoniae

    2008-01-01

    Automüüjate TOP 35. Vt. samas: Signe Sillasoo. Järelturg kukkus 15%; Signe Sillasoo intervjuu Scania Eesti AS-i tegevjuhi Janno Karuga; Tiit Lillipuu. Müüjad üritavad lattu seisma jäänud sõidukeid kiirelt maha müüa; Lars Fredrik Johannes Kjellgren. Tarbesõidukite turul toimub kainenemine; Kadrin Karner. United Motors: meie import kasvab; ABC Motors: meil läheb hästi

  7. Imaging in drug discovery and early clinical trials

    National Research Council Canada - National Science Library

    Rudin, M

    2005-01-01

    ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Imaging modalities: principles and information content Tobias Schaeffter ... 15 Magnetic resonance and fluorescence based molecular imaging technologies David...

  8. Signal processing for mobile communications handbook

    CERN Document Server

    Ibnkahla, Mohamed

    2004-01-01

    INTRODUCTIONSignal Processing for Future Mobile Communications Systems: Challenges and Perspectives; Quazi Mehbubar Rahman and Mohamed IbnkahlaCHANNEL MODELING AND ESTIMATIONMultipath Propagation Models for Broadband Wireless Systems; Andreas F. Molisch and Fredrik TufvessonModeling and Estimation of Mobile Channels; Jitendra K. TugnaitMobile Satellite Channels: Statistical Models and Performance Analysis; Giovanni E. Corazza, Alessandro Vanelli-Coralli, Raffaella Pedone, and Massimo NeriMobile Velocity Estimation for Wireless Communications; Bouchra Senadji, Ghazem Azemi, and Boualem Boashash

  9. Gross and fine motor function in fibromyalgia and chronic fatigue syndrome

    OpenAIRE

    Rasouli, Omid; Fors, Egil Andreas; Borchgrevink, Petter Chr.; Öhberg, Fredrik; Stensdotter, Ann-Katrin

    2017-01-01

    Omid Rasouli,1,2 Egil A Fors,3 Petter Chr Borchgrevink,4,5 Fredrik Öhberg,6 Ann-Katrin Stensdotter1 1Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; 2Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; 3Department of Public Health and Nursing, General Practice Research Unit, Norwe...

  10. Avgang 2017: Don Giovanni i Operaen

    OpenAIRE

    2017-01-01

    Opera av W.A. Mozart, med våre MA-studenter og gjester. Medvirkende: Dagfinn Andersen (MA2), Emil Havold Næshagen (MA1), Hanne Korsbrekke Askeland (MA2), Nora Oleanne Sårheim (MA2?), Sara Aasen (MA2), Marcela Randem (MA1), Eilert Hasseldal (MA1). Gjester: Eirik Grøtvedt, Per Lindström, Pavels Trofimiks. Kostymer: Fredrik Straum Floen. Dessuten medvirker kor (NMH), strykere (Ensemble Allegri) og blåsere (Stabsmusikken i Oslo)

  11. A Vibration-Based Approach for Stator Winding Fault Diagnosis of Induction Motors: Application of Envelope Analysis

    Science.gov (United States)

    2014-10-02

    through a low-pass and an anti-aliasing filter embedded in each channel of the NI data acquisition system . Doing the tests in this way ensures that the...Ompusunggu 2 , Zongchang Liu 1 , Hossein D. Ardakani 1 , Fredrik Petré 2 , and Jay Lee 1 1 NSF I/UCRC Center for Intelligent Maintenance Systems (IMS...Cincinnati, OH, 45221,USA jinco@mail.uc.edu liuzc@mail.uc.edu davarihn@mail.uc.edu jay.lee@uc.edu 2 Flanders’ Mechatronics Technology Centre (FMTC

  12. Nuevas observaciones sobre un tercer foco de fiebre petequial en el hemisferio americano

    Directory of Open Access Journals (Sweden)

    Luis Patiño Camargo

    1941-11-01

    Full Text Available Se ha localizado un foco endémico de Rickettsiasis y se ha denominado fiebre petequial de Tobia, en el interior de Colombia, en zona rural calida de la hoya del Magdalena, a 118 kilómetros de Bogotá. La comarca es fértil, pero las condiciones de vida humana son precarias. El índice de mortalidad por la fiebre petequial de Tobia, es de 95%. Ocurre principalmente en individuos de 20 a 29 años de edad, sin distincion de sexos. Hay epidemias familiares. Las gentes considerando que el contagio reside en las chozas y enseres, cuando se repiten las muertes, incineran las viviendas. Abundan ectoparásitos humanos y animales.

  13. PARTNER project: Trained to battle cancer with particles

    CERN Multimedia

    2009-01-01

    The four CERN students participating in the PARTNER project. From left to right: Daniel Abler (Germany), Faustin Laurentiu Roman (Romania), Vassiliki Kanellopoulos (Greece/Germany) and Till Tobias Boehlen (Germany).

  14. Marketing with changed media habits : A qualitative study about what small businesses think about digital marketing

    OpenAIRE

    Hoffner, Fredrik; Maliqi, Petrit; Svensson, Jesper

    2015-01-01

    Sammanfattning Titel: Marknadsföring med ändrade medievanor: En kvalitativ studie om småföretags syn på digital marknadsföring. Författare: Fredrik Hoffner, Petrit Maliqi och Jesper Svensson Handledare: Institution: Managementhögskolan, Blekinge Tekniska Högskola Kurs: Kandidatarbete i Företagsekonomi, 15 högskolepoäng Syfte: Syftet med arbetet är att undersöka och analysera om småföretag inom byggbranschen anpassar sig till de ändrade medievanorna, samt varför eller varför inte de väljer att...

  15. Festivali erinevad palged / Niina Kotsarenko ; tõlk. Madis Kolk

    Index Scriptorium Estoniae

    Kotsarenko, Niina

    2007-01-01

    Mõnedest selleaastasele teatrifestivalile "Talveöö unenägu 2006" iseloomulikest joontest. Erinevatest meistriklassidest, lühidalt etendustest: "Söör Vantes. Donki Hot" - lavastaja Dmitri Krõmovislandi, "Saja-aastane maja" Fru Emilia Teatri esituses, jaapanlase Issei Ogata monoetendus "Linnaelu kataloog" - lavastaja Yuzo Morita, Ghana tantsuansambli Kusum Gboo tantsusetendus "Somu" Richard Danguah lavastuses. Vene teatrikriitikustNatalja Krõmovast, tema sidemetest Eestiga ja tema raamatu "Nimed" presentatsioonist Linnateatris. Lk. 36-38 lühiintervjuud lavastaja Dmitri Krõmovi, tõlkija ja dramaturg Fredrik Linde ning festivali kunstilise juhi Jaanus Rohumaaga

  16. Effects of Peer Group Counselling and Sex on the Self -Concept

    African Journals Online (AJOL)

    Elizabeth

    A pre-test, post test, control group design was employed in the study. Sixty-eight ... adults (Hatcher, Nadeau, Walsh, Reynolds, Galea & Marze, 1994; Lane,. 1999; and Tobias ..... APDI, Ibadan: Maritime Printers' Psychological Publications.

  17. SENTIDO FILOSÓFICO NO BRASIL DOS PRIMEIROS DEBATES ACERCA DA RELAÇÃO ENTRE MENTE E CORPO PHILOSOPHICAL MEANING OF THE EARLIER DISCUSSIONS ON MIND AND BODY RELATIONSHIP IN BRAZIL

    Directory of Open Access Journals (Sweden)

    Leonardo Ferreira Almada

    2010-10-01

    Full Text Available

    Nosso objetivo é destacar o sentido filosófico no Brasil dos primeiros debates suscitados pela ideia de uma psicologia científica. Para tanto, trabalharemos com os textos de dois autores em especial, Gonçalves de Magalhães e Tobias Barreto. Nosso interesse é o de demonstrar em que sentido estes filósofos foram capazes de oferecer oposição a uma tendência positiva vigente na Psicologia e, ao mesmo tempo, superar o caráter contemplativo da consciência de si inerente à Psicologia sob a égide dos Jesuítas, e em vista da necessidade de modernização filosófica no Brasil. Ao mesmo tempo, pretendemos mostrar que, a despeito da crítica de Tobias a Magalhães, ambos souberam reconhecer a significação do naturalismo em Psicologia, especialmente no que diz respeito à tarefa de inserir o pensamento brasileiro nos rumos da filosofia ocidental.

    Our aim is to point out the philosophical meaning in Brazil of the earlier discussions about the nature of Scientific Psychology. Therefore, we will work in particular with texts of two authors, Gonçalves de Magalhães and Tobias Barreto. Our interest it to demonstrate in what sense these philosophers were able to offer opposition to a current positive trend in Psychology and the same time, overcome the contemplative character of self-consciousness inherent in Psychology under the aegis of the Jesuits, in view of need for philosophical modernization in Brazil. At the same time, we intend to show that, despite the criticism of Tobias to Magalhães, both know recognize the significance of the naturalism in Psychology, especially with regard to the task of entering the Brazilian thought in the course of Western Philosophy.

  18. Ginsbergi vennaskond, värskelt ühendatud / Marko Mägi

    Index Scriptorium Estoniae

    Mägi, Marko

    2005-01-01

    Poetry slami laadis luuleõhtul "Poesie United" esinesid 21. mail KuKu klubis Wehwalt Koslovsky, Tobias Hoffmann (Saksamaa), Ben Porter Lewis, Milo Martin (USA), Antoine Faure (Prantsusmaa), fs, Asko Künnap, Jürgen Rooste

  19. Skype as a third language

    DEFF Research Database (Denmark)

    Thestrup, Klaus

    2017-01-01

    Blogpost med video og tekst omkring hvordan Skype kan forståes som et tredje sprog. Video er produceret af Tobias Cramer og teksten af Klaus Thestrup. Pernille Elving har kommenteret og samlet blogposten....

  20. Unistus saab reaalsuseks / Kadri Kaldam

    Index Scriptorium Estoniae

    Kaldam, Kadri

    2008-01-01

    Arhitektuuri ja disaini veebiportaali Architonic salong Kölni mööblimessil. Projekteerija: LAVA (Laboratory for Visionary Architecture, Stuttgart, Sydney). Arhitektid: Tobias Wallisser, Chris Bosse. Loov meeskond: Kadri Kaldam, Stephan M. Albrecht, Kristof Gavrielides

  1. An Anthropologist Looks at Malaria | Tobias | South African Medical ...

    African Journals Online (AJOL)

    Also, malaria may be associated with the lower levels of ATP (adenosine triphosphate) in the red blood cells of Blacks. Man's cultural evolution and especially the adoption of agriculture - may have played a big part in the establishment of areas of malarial hyperendemicity. Thus, indirectly, malaria may have helped the early ...

  2. Poesie United toob kirjanduspeo

    Index Scriptorium Estoniae

    2005-01-01

    23. mail toimub Tartus rahvusvaheline kirjanduspidu "International spoken word subversion 2005" eesti, saksa, prantsuse ja ameerika sõnakunstnikega: Wehwalt Koslovsky, Tobias Hoffmann, Ben Porter Lewis, Milo Martin, Antoine Faure. Vt ka Postimees, 21. mai, lk. 26

  3. Maru ühendatud : Poesie United esines Tartus / Priit Kruus

    Index Scriptorium Estoniae

    Kruus, Priit

    2005-01-01

    23. mail esinesid Tartus saksa, ameerika, prantsuse ja eesti luuletajad spoken word-kirjandusüritusega "Poesie united". Osalesid Wehwalt Koslovsky, Tobias Hoffmann, Milo Martin, Ben Porter Lewis, Antoine Faure, Jürgen Rooste, Asko Künnap ja fs

  4. Fulltext PDF

    Indian Academy of Sciences (India)

    stage when we can regard our methodology to be slightly more reliable than betting .... been corrected by feeding the observational data of polar fields into the theoretical model. .... Tobias, S., Hughes, D., Weiss, N. 2006, Nature, 442, 26.

  5. The braconid parasitoids (Hymenoptera: Braconidae) of Kermania pistaciella Amsel (Lepidoptera: Tineidae: Hieroxestinae) in Iran

    NARCIS (Netherlands)

    Achterberg, van C.; Mehrnejad, M.R.

    2002-01-01

    Two species of Braconidae (Chelonus kermakiae (Tobias, 2001) (Cheloninae) and Centistidea pistaciella spec. nov. (Miracinae)) have been reared from the pistachio twig borer moth (Kermania pistaciella Amsel) (Tineidae). Both species are described and illustrated; Centistidea pistaciella spec. nov. is

  6. First report of the genus Coeliniaspis Fischer (Hymenoptera, Braconidae, Alysiinae) from China and Russia

    NARCIS (Netherlands)

    Zheng, M.-L.; Chen, J.-H.; Achterberg, van C.

    2017-01-01

    Coeliniaspis Fischer, 2010 (Braconidae, Alysiinae, Dacnusini) is recorded from China and Russia for the first time. Coeliniaspis insularis (Tobias, 1998) is reported from China (Fujian), redescribed and illustrated. A key to the species of the genus Coeliniaspis Fischer is added. Coeliniaspis

  7. Inflammatory bowel disease Cape Town, 1975-1980

    African Journals Online (AJOL)

    1983-02-12

    Patients with hepatobiliary complications are being reported in a companion paper by Tobias el al. J) In addition to the 3 mentioned above,S patients died during this study; 2 had an acute fulminating course, 1 had a lymphoma ...

  8. Ka luule võib olla tantsitav / Aija Sakova

    Index Scriptorium Estoniae

    Sakova, Aija, 1980-

    2005-01-01

    21. ja 23. mail esinevad Tallinnas ja Tartus saksa, ameerika, prantsuse ja eesti luuletajad spoken word-kirjandusüritustega "Poesie united". Osalevad Wehwalt Koslovsky, Tobias Hoffmann, Milo Martin, Ben Porter Lewis, Antoine Faure, Jürgen Rooste, Asko Künnap ja fs

  9. A novel CYP1A1 gene polymorphism and the risk of head and neck ...

    African Journals Online (AJOL)

    Administrator

    2011-06-15

    Jun 15, 2011 ... 5274 Afr. J. Biotechnol. The principal enzymes ..... Amalio T, Paul I, Francine M, Tobias S, Thomas B (1993). Direct, automated .... Olshan A, Weissler M, Watson MA, Bell D (2000). GSTM1, GSTT1, ... Jr. JF, editors. Cancer ...

  10. Feminist Social Justice Orientation: An Indicator of Optimal Functioning?

    Science.gov (United States)

    Moradi, Bonnie

    2012-01-01

    This article underscores several themes evident in Yoder, Snell, and Tobias's research; these include the conceptualization of feminism and social justice as inextricably linked, the conceptualization and operationalization of optimal functioning at intrapersonal, interpersonal, and collective levels, and potential connections and disconnections…

  11. Scopus: Journal of East African Ornithology - Vol 36, No 2 (2016)

    African Journals Online (AJOL)

    Avifauna of Boni-Dodori National Reserves, Lamu and Garissa Counties, Kenya · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Tobias Otieno, Timothy Mwinami, Martha Ngala, Sandy Oduor, Fleur Ng'weno, Simon Musila, Charles Kimwele, 1-16 ...

  12. Saksa vaim Kunstihoones

    Index Scriptorium Estoniae

    2001-01-01

    Fotokunsti väljapanek "Ajastu vaim. Saksa moefotod 1945-1995". Kuraator F. C Gundlach. Esindatud kunstnikud Helmut Newton, Wolfgang Tillmans, Jürgen Teller, Charlotte Rohrbach, Norbert Leonard, Willy Maywald, Regi Relang, Hubs Flöter, Herbert Tobias, Rico Puhlmann, Will McBride, Charlotte March.

  13. Interview with Kortney Ryan Ziegler of the Trans*H4CK Project

    DEFF Research Database (Denmark)

    Raun, Tobias

    2014-01-01

    TSQ New Media editor Tobias Raun interviews Kortney Ryan Ziegler, the organizer of the Trans*H4CK hackathon, which took place in Oakland, California, in September 2013. The hackathon brought forty transgender, gender nonconforming, cisgender, and queer people together to create digital tools...

  14. International Disability Educational Alliance (IDEAnet)

    Science.gov (United States)

    2011-03-23

    Apomediation, and Openness. Journal of Medical Internet Research . July-September; 10(3): e22. 14 Kamel Boulous, Maged N. and Wheeler, Steve (2007...Participation, Apomediation, and Openness. Journal of Medical Internet Research . July-September; 10(3): e22. Fletcher, J.D.,;Tobias, S.; and Wisher, R. (2007

  15. Eesti Ekspressi singel 2. Eesti Ekspressi singel 3

    Index Scriptorium Estoniae

    2008-01-01

    Koos 30. okt. Eesti Ekspressiga ilmub tänavuse Superstaari konkurssi võitja Jana Kase esimene singel, rock-lugu "Leaving You For Me" (loonud Rootsis tegutsev laulukirjutajate-produtsentide tiim Tony Malm, Per Eklund, Fredrik Björk ja Martin Kesici, produtseerinud Alar Kotkas, Ilmar Laisaar, Pearu Paulus). 6. nov. ilmuva ajalehe vahel on metal-bändi Metsatöll singel "Merehunt" lisalooga "Alle-aa". Kõik singlid mängitakse ette Ekspressi raadiosaates "Magneet" neljapäeviti Kuku raadios algusega kell 13.00 ning kõik artistid esinevad singli ilmumispäeva õhtul telesaates "Värske Ekspress" neljapäeviti TV3-s algusega 21.30

  16. From hadron therapy to cosmic rays: a life in biophysics

    CERN Multimedia

    Christine Sutton

    2014-01-01

    In 1954 – the year CERN was founded – another scientific journey began at what is now the Lawrence Berkeley National Laboratory. Beams of protons from a particle accelerator were used for the first time by John Lawrence – a doctor and the brother of Ernest Lawrence, the physicist after whom the Berkeley lab is named – to treat patients with cancer. For many years, Eleanor Blakely has been one of the leaders of that journey. She visited CERN last week and spoke with the Bulletin about her life in biophysics.   Use of the cylcotron beam to mimic "shooting stars" seen by astronauts. Black hood on subject Cornelius Tobias keeps out light during neutron irradiation experiment at the 184-inch accelerator. Helping to position Tobias in the beam line are (left to right) John Lyman of Biomedical Division, and Ralph Thomas of Health Physics. (Photo courtesy of Lawrence Berkeley National Laboratory.) Interested in biophysics, which was still a new...

  17. Angels and Demons in the Book of Jubilees

    NARCIS (Netherlands)

    Ruiten, Jacques van; Reiterer, F.V.; Nicklas, T.; Schöpflin, K.

    2007-01-01

    Jacques van Ruiten, “Angels and Demons in the Book of Jubilees,” in Angels: The Concept of Celestial Beings – Origins, Development and Reception (ed. Friedrich V. Reiterer, Tobias Nicklas, and Karin Schöpflin; Deuterocanonical and Cognate Literature Yearbook 2007; Berlin and New York: de Gruyter,

  18. Bastard Culture! : How User Participation Transforms Cultural Production

    NARCIS (Netherlands)

    Schäfer, Mirko Tobias

    2011-01-01

    Nieuwe online technologieën brengen een grote belofte van bevrijding met zich mee. Leken en amateurs worden enthousiast als helden van het digitale tijdperk omhelsd. In dit boek analyseert Mirko Tobias Schäfer hoe de participatie van gebruikers daadwerkelijk vorm krijgt door deze in de context te

  19. Bastard Culture! How User Participation Transforms Cultural Production

    NARCIS (Netherlands)

    Schäfer, M.T.

    2011-01-01

    Nieuwe online technologieën brengen een grote belofte van bevrijding met zich mee. Leken en amateurs worden enthousiast als helden van het digitale tijdperk omhelsd.
    In dit boek analyseert Mirko Tobias Schäfer hoe de participatie van gebruikers daadwerkelijk vorm krijgt door deze in de context

  20. The Effects of Captions on EFL Learners' Comprehension of English-Language Television Programs

    Science.gov (United States)

    Rodgers, Michael P. H.; Webb, Stuart

    2017-01-01

    The Multimedia Principle (Fletcher & Tobias, 2005) states that people learn better and comprehend more when words and pictures are presented together. The potential for English language learners to increase their comprehension of video through the use of captions, which graphically display the same language as the spoken dialogue, has been…

  1. Finding Optimal Functioning in a Sexist World: A Social Justice Challenge

    Science.gov (United States)

    Yoder, Janice D.

    2012-01-01

    Focusing in on a point of convergence among the three reactions generously shared regarding Yoder, Snell, and Tobias (2012), the author revisits our original interpretation of the configuration we labeled awakening feminism as well as its implications for counseling practice. Rather than regard awakening feminism as a distressful stage through…

  2. Work-Life Balance: the Links with Management Practices and Productivity

    OpenAIRE

    Nick Bloom; Tobias Kretschmer; John Van Reenen

    2006-01-01

    Does good management and higher productivity come at the expense of work-life balance? Or is good work-life balance an important component of the management of successful firms? New research by Nick Bloom, Tobias Kretschmer and John Van Reenen finds evidence for a hybrid view between these two polar extremes.

  3. Angels and Demons in the Book of Jubilees

    OpenAIRE

    Ruiten, Jacques van; Reiterer, F.V.; Nicklas, T.; Schöpflin, K.

    2007-01-01

    Jacques van Ruiten, “Angels and Demons in the Book of Jubilees,” in Angels: The Concept of Celestial Beings – Origins, Development and Reception (ed. Friedrich V. Reiterer, Tobias Nicklas, and Karin Schöpflin; Deuterocanonical and Cognate Literature Yearbook 2007; Berlin and New York: de Gruyter, 2007), 585-609.

  4. Another Perspective: A Response to "Toward Convergence"

    Science.gov (United States)

    Regelski, Thomas A.

    2013-01-01

    This response by Thomas A. Regelski was solicited to complement the lead article in this issue, "Toward Convergence: Adapting Music Education to Contemporary Society and Participatory Culture" by Evan S. Tobias. The author notes that many interesting and vital questions and alternatives that are often studiously ignored, overlooked, or taken for…

  5. Spørgsmålet om teknikken og naturen

    DEFF Research Database (Denmark)

    Skiveren, Tobias; Gregersen, Martin

    2015-01-01

    Med afsæt i økokritikken kortlægger Tobias Skiveren og Martin Gregersen to strømninger i de aktuelle filmiske iscenesættelser af naturkatastrofen. Gennem analytiske punktnedslag i Lars von Triers "Melancholia", Scett Derricksons "The day the Earth Stood Still", Jan de Bonts "Twister" og Andrew...

  6. Muusikamaailm : Uus muusikasaal Philadelphias. Elgari teostekogu jätkatakse. Mortier tuleb ka Pariisi. Salonen loovutas Suomi-palkinto. Uusooper Dallases / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Philadelphia sai uue kontserdisaali. Londoni kirjastus Novello jätkab Edward Elgari kogutud teoste väljaandmist. Belgia teatrimees ja ooperiadministraator Gerard Mortierist saab Ruhri kunstidetriennaali juht. Esa-Pekka Salonen loovutas oma 100 000margalise preemia kolmele noorele soome heliloojale. Dallase Ooperis tuli maailmaesiettekandele USA helilooja Tobias Pickeri ooper "Therese Raquin"

  7. Developing a Professional Learning Community among Preservice Teachers

    Science.gov (United States)

    Bond, Nathan

    2013-01-01

    This action research study examined the development of a professional learning community (PLC) among 20 preservice secondary teachers as they met regularly during a semester-long, field-based education course to share artifacts of learning from their professional portfolios. The PLC model described by Hord and Tobia (2012) served as a framework…

  8. Dicty_cDB: Contig-U14279-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Dictyostelium discoideum cDNA clone:ddc30k04, 5' ... 200 6e-48 1 ( EW967860 ) LS_13_N05_T7 Headlice composite...tobia irritans 1st Instar Larvae H... 42 3.5 1 ( EW966307 ) SFHL_01_A10_T7 Headlice composite library with a

  9. Persisting aphasia, cerebral dominance, and painting in the famous artist Carl Fredrik Reuterswärd.

    Science.gov (United States)

    Colombo-Thuillard, F; Assal, G

    2007-01-01

    What about artistic creativity following a cerebral lesion? We studied the case of a prominent right-handed Swedish painter and sculptor who suffered a cerebral hemorrhage at the age of 55 years. The patient displayed a lesion of the left capsular lenticular region, which resulted in a right hemiplegia and sensory loss, with aphasia of the subcortical type. The linguistic impairments recovered well but at 1 year postonset, the right hand was still completely paralyzed. After a period of a few weeks, during which the patient refused to use his nondominant hand, he produced his first left-handed drawing, and by 1 year postonset, he had once again resumed an intensive artistic activity using his nondominant hand. The pictorial works were reviewed by several renowned art specialists: changes of style and even of contents were judged without loss of artistic quality. The result was described as a gain in emotional and artistic intensity. We discuss our observation in the context of the literature and focus on the crucial role of cerebral dominance and hand preference. We conclude that pictorial creativity and language are distinct forms of expressions.

  10. Case report

    African Journals Online (AJOL)

    animal surgery.r.Ed. St. Louis: Elsevier Saunders, 2004,PA 72-477. VIANNA, M.L. and TOBIAS, K.M. (2005):. Atresia ani in the dog: Aretrospective study. J Am Anim Hosp Assoc. 41:317-322. WYKES, P.M. and OLSON, P.N. (2003). Vagina, vestibule, and vulva. In: Textbook of Small Animal Surgery. Slatter DH, editor.

  11. Eesti Ekspressi singel 1. Eesti Ekspressi singel 2

    Index Scriptorium Estoniae

    2008-01-01

    Kaheksa nädala jooksul ilmub koos Eesti Ekspressiga ajalehekioskitesse üks Eesti artisti singelplaat, esimene neist on Tõnis Mägi ja Noorkuu "Pühendus" (ilmub 23. okt. lehe vahel, a-capella esituses). Koos 30. okt. Ekspressiga ilmub tänavuse Superstaari konkurssi võitja Jana Kase esimene singel, rock-lugu "Leaving You For Me" (loonud Rootsis tegutsev laulukirjutajate-produtsentide tiim Tony Malm, Per Eklund, Fredrik Björk ja Martin Kesici, produtseerinud Alar Kotkas, Ilmar Laisaar, Pearu Paulus). Kõik singlid mängitakse ette Ekspressi raadiosaates "Magneet" neljapäeviti Kuku raadios algusega kell 13.00 ning kõik artistid esinevad singli ilmumispäeva õhtul telesaates "Värske Ekspress" neljapäeviti TV3-s algusega 21.30

  12. A Model Stitching Architecture for Continuous Full Flight-Envelope Simulation of Fixed-Wing Aircraft and Rotorcraft from Discrete Point Linear Models

    Science.gov (United States)

    2016-04-01

    AND ROTORCRAFT FROM DISCRETE -POINT LINEAR MODELS Eric L. Tobias and Mark B. Tischler Aviation Development Directorate Aviation and Missile...Stitching Architecture for Continuous Full Flight-Envelope Simulation of Fixed-Wing Aircraft and Rotorcraft from Discrete -Point Linear Models 5...of discrete -point linear models and trim data. The model stitching simulation architecture is applicable to any aircraft configuration readily

  13. Extraction of toluene from aliphatic compounds using an ionic liquid as solvent: Influence of the alkane on the (liquid + liquid) equilibrium

    International Nuclear Information System (INIS)

    Gonzalez, Emilio J.; Calvar, Noelia; Dominguez, Irene; Dominguez, Angeles

    2011-01-01

    Research highlights: → An ionic liquid was analyzed as solvent for extraction of toluene from alkanes. → Liquid-liquid equilibrium data were measured at 298.15 K and atmospheric pressure. → Selectivity and solute distribution ratio were obtained and compared with literature. → The Othmer-Tobias equation was used to ascertain the experimental LLE data. → Experimental data were correlated using NRTL and UNIQUAC models. - Abstract: In this paper, the feasibility of using 1-ethyl-3-methylimidazolium ethylsulfate ionic liquid, [EMim][ESO 4 ], as solvent for the extraction of toluene from aliphatic compounds (hexane, heptane, octane, or nonane) was analyzed. (Liquid + liquid) equilibrium (LLE) data for the ternary systems {alkane (1) + toluene (2) + [EMim][ESO 4 ] (3)} were measured at T = 298.15 K and atmospheric pressure. Selectivity and solute distribution ratio were calculated from the experimental LLE data, and the obtained values were compared to those previously reported using other ionic liquids and sulfolane. The degree of consistency of the experimental LLE data was ascertained using the Othmer-Tobias equation. Finally, the experimental LLE data were satisfactorily correlated with NRTL and UNIQUAC models.

  14. Sustaining growth and profitability--The Economist fifth annual pharmaceuticals conference. 12-13 November 1998, London, UK.

    Science.gov (United States)

    Muhsin, M

    1999-01-01

    This two-day conference, organized by The Economist, focused on R and D productivity, strategic and innovative methodologies, M and A activities and knowledge management within the pharmaceutical industry. Key speakers within the industry addressed these issues to an audience of approximately 100 healthcare business executives. The first day was chaired by Barrie Haigh (Quintiles Translational Corp) and the second day by Tobias Rooney (Gemini Consulting).

  15. Dictionnaire biographique des musiciens / Baker, Theodore, Slonimsky, Nicolas

    Index Scriptorium Estoniae

    Baker, Theodore

    1995-01-01

    Eesti muusikutest: Aarne, Els (lk. 1). Aav, Evald (1). Aavik, Juhan (2). Eller, Heino (1149). Ernesaks, Gustav (1180). Järvi, Neeme (1951). Kapp. Artur (2036). Kapp, Eugen (2036). Kapp, Villem (2037). Kasemets, Udo (2050-2051). Mägi [Myagi], Ester (2923). Pärt, Arvo (3114-3115). Rääts, Jaan (3321). Saar, Mart (3558). Sumera, Lepo (4099). Tamberg, Eino (4151). Tobias, Rudolf (4240). Tubin, Eduard (4288)

  16. Semiannual Report, April 1, 1989 through September 30, 1989 (Institute for Computer Applications in Science and Engineering)

    Science.gov (United States)

    1990-02-01

    noise. Tobias B. Orloff Work began on developing a high quality rendering algorithm based on the radiosity method. The algorithm is similar to...previous progressive radiosity algorithms except for the following improvements: 1. At each iteration vertex radiosities are computed using a modified scan...line approach, thus eliminating the quadratic cost associated with a ray tracing computation of vortex radiosities . 2. At each iteration the scene is

  17. A new OH5 reconstruction with an assessment of its uncertainty.

    Science.gov (United States)

    Benazzi, Stefano; Bookstein, Fred L; Strait, David S; Weber, Gerhard W

    2011-07-01

    The OH5 cranium, holotype of Paranthropus boisei consists of two main portions that do not fit together: the extensively reconstructed face and a portion of the neurocranium. A physical reconstruction of the cranium was carried out by Tobias in 1967, who did not discuss problems related to deformation, although he noted a slight functional asymmetry. Nevertheless, the reconstructed cranium shows some anomalies, mainly due to the right skewed position of the upper calvariofacial fragment and uncertainty of the relative position of the neurocranium to the face, which hamper further quantitative analysis of OH5's cranial geometry. Here, we present a complete virtual reconstruction of OH5, using three-dimensional (3D) digital data, geometric morphometric (GM) methods and computer-aided design (CAD) techniques. Starting from a CT scan of Tobias's reconstruction, a semi-automatic segmentation method was used to remove Tobias's plaster. The upper calvariofacial fragment was separated from the lower facial fragment and re-aligned using superposition of their independent midsagittal planes in a range of feasible positions. The missing parts of the right hemiface were reconstructed using non-uniform rational basis-spline (NURBS) surface and subsequently mirrored using the midsagittal plane to arrive at a symmetrical facial reconstruction. A symmetric neurocranium was obtained as the average of the original shape and its mirrored version. The alignment between the two symmetric shapes (face and neurocranium) used their independent midsagittal plane and a reference shape (KNM-ER 406) to highly reduce their degrees of freedom. From the series of alternative reconstructions, we selected the middle of this rather small feasible range. When reconstructed as a range in this way, the whole cranial form of this unique specimen can be further quantified by comparative coordinate-based methods such as GM or can be used for finite element modeling (FEM) explorations of hypotheses about

  18. Review: Wilfried Breyvogel (Ed.) (2005). Einführung in Jugendkulturen. Veganismus und Tattoos [Introduction to Youth Cultures. Veganism and Tattoos

    OpenAIRE

    Sebastian Schröer

    2007-01-01

    Wilfried BREYVOGEL's introductory textbook combines three individual texts. As well as an historic overview of diverse "youth cultures" there are two extensive contributions devoted to veganism (Thomas SCHWARZ) and tattoos (Tobias LOBSTÄDT). BREYVOGEL's contribution is a literature-based study, whereas SCHWARZ and LOBSTÄDT present work based on original research. However, expectations of an introductory textbook are disappointed because the book does not contain a well-founded and "tight" the...

  19. Questionnaire-based evaluation of everyday competence in older adults

    OpenAIRE

    Kalisch, Tobias

    2011-01-01

    Tobias Kalisch1, Julia Richter3, Melanie Lenz1, Jan-Christoph Kattenstroth2, Izabela Kolankowska2, Martin Tegenthoff1, Hubert R Dinse21Department of Neurology, BG-Kliniken Bergmannsheil, 2Neural Plasticity Lab, Institute for Neuroinformatics, Department of Theoretical Biology, 3Faculty of Psychology, Department of Methods, Diagnostics and Evaluation, Ruhr-University Bochum, GermanyBackground: Gerontological research aims at understanding factors that are crucial for mediating “succe...

  20. Creating marketing strategies for wedding business unit of Amari Atrium Hotel

    OpenAIRE

    Suvagondha, Apiwat; Soparat, Pattamaporn

    2008-01-01

    Abstract Date: May 29, 2008 Course: Master Thesis (EFO 705) Authors: Apiwat Suvagondha 790819 Pattamaporn Soparat 840216 Tutor: Tobias Eltebrandt Title: Creating marketing strategies for wedding business unit of Amari Atrium Hotel Problem: What should be marketing strategies for wedding business unit of Amari Atrium Hotel? Purpose: The aim of our thesis is to analyze the wedding market in Bangkok together with consumer purchasing behavior of Thai’s couple regarding to wedding ceremony in orde...

  1. Formaalne kuraatorinäitus versus huvitavad rahvuspaviljonid / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2009-01-01

    53. Veneetsia biennaalist. Peanäitusest "Making Worlds"/"Tehes maailmu", kuraator Daniel Birnbaum. Eestit esindab Kristina Norman projektiga "After-War". Lühidalt Hispaania (Miquel Barcelo), Iiri (kunstnikeduo Kennedy Browne), Inglise (Steve McQueen), Prantsuse (Claude Leveque), Saksa (Liam Gillick), Serbia (Zoran Todorovic), Taani ja Põhjamaade, Tšehhi ja Slovaki (Roman Ondak), Tšiili (Ivan Navarro), USA (Bruce Nauman) paviljonidest. Biennaali peapreemiad pälvisid USA paviljon, saksa kunstnik Tobias Rehberger ja rootsi kunstnik Nathalie Djuberg

  2. Hovdabrekka Project II

    DEFF Research Database (Denmark)

    Hovden, Jan

    2008-01-01

    The Hovdabrekka group is a group of nordic researchers doing survey studies of Nordic journalism schools (2005,2008). This site is dedicated to information from this project. The current members are: Norway: Rune Ottosen,Gunn Bjørnsen and Jan Fredrik Hovden Sweden: Jenny Wiik Denmark: Ida Willig...... and Jannie Møller Hartley. Finland: Henrika Zilliacus-Tikkanen and Raimo Solokangas Former members: Jan Dyberg and Hanne Jørndrup (Denmark), Marina Ghersetti (Sweden) Project Hovdabrekka originated at the Nordic conference for journalist teachers at Hovdabrekka, Iceland September 2004, where a small group...... of scientists/lecturers assembled with a desire to do a comparative quantitative study of students at Nordic journalism schools. Until very recently, there existed little systematic knowledge on the students of journalism in the Nordic countries. For these reasons, the Hovdabrekka group planned and sent out...

  3. Die Reichstagswahl 2006 – Eine Zäsur in der schwedischen Parteiengeschichte

    Directory of Open Access Journals (Sweden)

    Sven Jochem

    2006-01-01

    Full Text Available Sweden is the social democratic model in Europe. Despite good economic conditions, the social democratic minority government under the leadership of Göran Persson lost the election on 17th September 2006. Since then, a four party coalition headed by the conservative Prime Minister Fredrik Reinfeldt is governing Sweden. In this contribution the electoral campaign as well as the electoral result is analysed. It will be shown that there occurred a paradigm shift in Swedish party history. A majority government has managed to overcome the programmatic differences in the bourgeois camp. It is further argued that the new government will hardly change the Swedish model at once. However, small but decisive reform steps will alter the contours of the Swedish welfare state and will make it more similar to welfare states in Continental Europe.

  4. The management of operational value at risk in banks / Ja'nel Tobias Esterhuysen

    OpenAIRE

    Esterhuysen, Ja'nel Tobias

    2006-01-01

    The measurement of operational risk has surely been one of the biggest challenges for banks worldwide. Most banks worldwide have opted for a value-at-risk (VaR) approach, based on the success achieved with market risk, to measure and quantify operational risk. The problem banks have is that they do not always find it difficult to calculate this VaR figure, as there are numerous mathematical and statistical methods and models that can calculate VaR, but they struggle to understa...

  5. Internet cases in EU private international law - developing a coherent approach / Tobias Lutzi

    Index Scriptorium Estoniae

    Lutzi, Tobias

    2017-01-01

    Internetiühenduse mõjust rahvusvahelisele eraõigusele ja selle toetumisest geograafilistele punktidele. Probleemidest rahvusvahelist eraõigust reguleerivate rahvusvaheliste õigusaktide valguses ja asjakohasest kohtupraktikast

  6. Reasons for elderly patients GP visits: results of a cross-sectional study

    OpenAIRE

    Frese, Thomas; Mahlmeister, Jarmila; Deutsch, Tobias; Sandholzer, Hagen

    2016-01-01

    Thomas Frese, Jarmila Mahlmeister, Tobias Deutsch, Hagen Sandholzer Department of General Practice, Medical Faculty, University of Leipzig, Leipzig, Germany Objective: The aim of this study is to describe the frequency of reasons for elderly patients visits to a general practice (GP) setting. Subjects and methods: Cross-sectional data from 8,877 randomly selected patients were assessed during a 1-year period by 209 GPs in the German federal state of Saxony. The reasons for visits, performed...

  7. Index to FAA Office of Aviation Medicine Reports: 1961 through 1998.

    Science.gov (United States)

    1999-01-01

    marihuana . AD775889 73-13 Tobias, J. V., and Irons, F. M: Reception of distorted speech. AD777564 73-14 Thackray, R. I., Jones, K. N., and...involved in midair collisions. ADAO16277 75-6 Lewis, M. F., Ferraro, D. P., Mertens, H. W., and Steen, J. A: Interaction between marihuana and...71-17. ... human tolerance, 62-6. ... marihuana effects on performance, 75-6. ... oxygen masks, efficiency of, 62-21, 66-7, 66-9, 66-20, 67-3, 67

  8. Adopted Koreans and the development of identity in the "third space"

    OpenAIRE

    Hübinette, Tobias

    2004-01-01

    Since 1953, 150,000 Korean children have been adopted to 15 main host countries in the West. They constitute the largest international adoptee group worldwide. An adopted Korean movement has existed on an international level since the 1990s and is today trying to formulate an identity and community of its own beyond Western adoption ideology and Korean nationalism. Tobias Hübinette outlines the history of international adoption from Korea, Western and Korean perspectives on international adop...

  9. Proceedings of the Frontiers of Retrovirology Conference 2016

    OpenAIRE

    Zurnic, Irena; H?tter, Sylvia; Lehmann, Ute; Stanke, Nicole; Reh, Juliane; Kern, Tobias; Lindel, Fabian; Gerresheim, Gesche; Hamann, Martin; M?llers, Erik; Lesbats, Paul; Cherepanov, Peter; Serrao, Erik; Engelman, Alan; Lindemann, Dirk

    2016-01-01

    Table of contents Oral presentations Session 1: Entry & uncoating O1 Host cell polo-like kinases (PLKs) promote early prototype foamy virus (PFV) replication Irena Zurnic, Sylvia H?tter, Ute Lehmann, Nicole Stanke, Juliane Reh, Tobias Kern, Fabian Lindel, Gesche Gerresheim, Martin Hamann, Erik M?llers, Paul Lesbats, Peter Cherepanov, Erik Serrao, Alan Engelman, Dirk Lindemann O2 A novel entry/uncoating assay reveals the presence of at least two species of viral capsids during synchronized HIV...

  10. Proceedings of the Frontiers of Retrovirology Conference 2016

    OpenAIRE

    Zurnic, Irena; Hütter, Sylvia; Lehmann, Ute; Stanke, Nicole; Reh, Juliane; Kern, Tobias; Lindel, Fabian; Gerresheim, Gesche; Hamann, Martin; Müllers, Erik; Lesbats, Paul; Cherepanov, Peter; Serrao, Erik; Engelman, Alan; Lindemann, Dirk

    2016-01-01

    Table of contents Oral presentations Session 1: Entry & uncoating O1 Host cell polo-like kinases (PLKs) promote early prototype foamy virus (PFV) replication Irena Zurnic, Sylvia Hütter, Ute Lehmann, Nicole Stanke, Juliane Reh, Tobias Kern, Fabian Lindel, Gesche Gerresheim, Martin Hamann, Erik Müllers, Paul Lesbats, Peter Cherepanov, Erik Serrao, Alan Engelman, Dirk Lindemann O2 A novel entry/uncoating assay reveals the presence of at least two species of viral capsids during synchronized HIV...

  11. The stuff of enlightening diagnoses; Stoff fuer erhellende Diagnosen

    Energy Technology Data Exchange (ETDEWEB)

    Huebner, Karl

    2017-07-01

    Doctors today already frequently rely on positron emission tomography - PET for short - in cancer diagnostics. However, in order to use this method for other diseases, too, they need suitable tracer substances containing radioactive fluorine-18 - a challenge for Tobias Ritter and his team at the Max Planck Institut fuer Kohlenforschung in Muelheim an der Ruhr. The chemists are searching for ways to label diverse molecules with fluorine-18 and thus expand the range of possibilities for medical specialists.

  12. The Relation of Batteries to Explosives.

    Science.gov (United States)

    1980-09-01

    addition, corrosion can occur within the system, slowly generating hydrogen gas by the reaction: Zn + H2 0 --- ZnO + H2 (4) In the lead dioxide-lead...277-305. 13Delahay, P., Tobias, C., ed., Advances in Electrochemistry and Electrochemical Engineering, Vol. 5 (New York: Wiley-Interscience...various anodes. 4-5 NSWC TR 80-455 TABLE I PASSIVATIIN FILMS ANODE MATERIAL Electrolyte Material Zinc Magnesium Lithium H2 0 ZnO MgO [Mg(OH) 2

  13. Index to FAA (Federal Aviation Administration) Office of Aviation Medicine Reports: 1961 through 1982,

    Science.gov (United States)

    1983-01-01

    endrin. AD431299 63-17 Tobias, J. V.: Application of a "relative" procedure to a problem in binaural beat perception. AD428899 63-18 Balke, B...distraction, 72-14. Audiology auditory fatigue, 63-19, 65-1, 65-2. binaural beat perception, 63-17. cockpit noise intensities, 68-21, 68-25. ear...recognition, 71-27, 71-32. impairment by sunscreen materials, 78-28. tests, 67-8. X-Chrom lens for improving, 78-22. Communication binaural beat perception

  14. Update on the REIPPPP, clean coal, nuclear, natural gas

    CSIR Research Space (South Africa)

    Milazi, Dominic

    2015-12-01

    Full Text Available , clean coal, nuclear, natural gas The Sustainable Energy Resource Handbook Volume 6 Dominic Milazi, Dr Tobias Bischof-Niemz, Abstract Since its release in 2011, the Integrated Resource Plan (IRP 2010-2030), or IRP 2010, has been the authoritative... text setting out South Africa’s electricity plan over the next 20 years. The document indicates timelines on the roll out of key supply side options such as renewable energy, the nuclear, natural gas and coal build programmes, as well as peaking...

  15. Equilibrium data on ethanol-water-solvent ternaries

    Directory of Open Access Journals (Sweden)

    I. Kirbaslar

    2000-06-01

    Full Text Available Experimental liquid-liquid equilibria of water-ethanol-1-nonanol and water-ethanol-1-decanol systems were investigated at 303.16± 0.20 K. The reliability of the experimental tie-line data was ascertained by using Othmer-Tobias and Hand plots. Distribution coefficients (Di and separation factors (S were evaluated for the immiscibility region. It is concluded that the solvents with high boiling point, 1-nonanol and 1-decanol, are suitable separating agents for dilute aqueous ethyl alcohol solutions.

  16. Towards Clean Diesel Engines. Second Symposium. Book of Abstracts.

    Science.gov (United States)

    1998-04-06

    E-Mail: choelle@bmw.co.at Rudolf HOLTBECKER R&D KoSt 7055 Wärtsilä NSD Switzerland Ltd. Postfach 414 CH-8401 Winterthur Switzerland Tel.: +41...49-5362 267 E-Mail: tim.strauss@volkswagen.de C. M. I. SPAANJAARS Dept. of Molecular + Laser Physics Rudolf STRUIS University of Nijmegen Paul...365 3017 Fax: +41-56-310 2199 Fax: +31-24-365 3311 E-Mail: struis@psi.ch E-Mail: charless@sci.kun.nl Gerrit SUCK Tobias STEINER Konzernforschung K

  17. To heal the mind's eye of hate--Dr. Ludwik Zamenhof.

    Science.gov (United States)

    Wincewicz, Andrzej; Sulkowska, Mariola; Sulkowski, Stanislaw

    2007-05-01

    Ludwik Zamenhof (1859-1917), born in Poland, invented and propagated Esperanto - an artificial, easy-to-learn language. Literally meaning "language of hope," Esperanto was constructed to avoid misunderstandings, establish communication and facilitate harmony among different nationalities. Simply, he wanted people to accept one another despite observed differences. He was a skilled ophthalmologist, but figuratively, he wished to heal the eyes of humankind to look without hate, just as the biblical Tobias removed the cataract from the corners of his father's eyes to restore his sight.

  18. Altar - jumala laud ja esindusobjekt / Reet Rast

    Index Scriptorium Estoniae

    Rast, Reet

    2005-01-01

    Altar kui kunstiline ülesanne. Altari teoloogiline sõnum. Püha õhtusöömaaeg - Kihelkonna kiriku altar (1591), Harju-Madise triptühhon (1631). Kristuse ristilöömine - Kärla kiriku altar (1591). Skulptuuriprogrammid, voorused. Keila kiriku altar (Tobias Heintze töökoda, 1632). Haapsalu Jaani kiriku altar (Joachim Winter, 1630). Ridala kiriku altar (Elert Thiele?, Berent Lorentz, 1678). Tallinna toomkiriku altar (Christian Ackermann, 1696, maalid: Ernst Wilhelm Londicer). Rootsi Mihkli kiriku altar (Joachim Armbrust, 1697). Juuru kiriku altar (Johann Siimsen, skulptuurid Quirinus Rabe, 1736). Bilbiograafia lk. 456-457

  19. The impact of society on Management Control Systems

    DEFF Research Database (Denmark)

    Greve, Jan; Ax, Christian; Dergård, Johan

    2014-01-01

    . This study contributes to accounting literature in three ways. First, it brings quantitative support to Whitley’s (1999a) theory about MCS as integrated parts of societal business systems. Second, it offers possible explanations to inconsistences in prior research and it also suggests the inclusion......‐Saxon economies and findings may be bounded to these societies. Authors: Jan Greve; Co-authors: Christian Ax; Johan Dergård; Tobias Johansson; Carsten Rohde; Torkel Strömsten; Jeanette Willert; Rolf Brühl; David Bedford; Angelo Ditillo; Andrea Dossi; Maurice Gosselin; Michael Hanzlick; Sophie Hoozee; Poul...

  20. Bankvärldens framtid : En studie kring hur banker utnyttjar den teknologiska utvecklingen och digitaliseringen av tjänster, samt dess påverkan på kundrelationer, förtroende och lojalitet

    OpenAIRE

    Grip, Sebastian; Hellström, Gustav; Skyttevall, Tobias

    2017-01-01

    Titel: Bankvärldens framtid: En studie kring hur banker utnyttjar den teknologiska utvecklingen och digitaliseringen av tjänster samt dess påverkan på kundrelationer, förtroende och lojalitet   Nivå: Kandidatuppsats i företagsekonomi   Akademi: Akademin för Ekonomi, Samhälle och Teknik, Mälardalens Högskola   Författare: Sebastian Grip, Gustav Hellström och Tobias Skyttevall (92/04/22), (94/02/28), (95/05/21) Handledare: Hadjikhani, Annoch   Datum: 05–06–17   Bakgrund: Att skapa en lojal kun...

  1. Studies on Synthesis and Dyeing Preformance of Acid Dyes Based on 4,7-Dihydroxy-1,10-Phenanthroline-2,9-Dione

    Directory of Open Access Journals (Sweden)

    B. V. Patel

    2008-01-01

    Full Text Available Some new azo acid dyes were prepared by coupling various diazotized acid components such as anthranilic acid, sulphanilic acid, laurent acid, peri acid, tobias acid, H-acid, J-acid, gamma acid, sulphotobias acid, 4-aminotoluiene-3-sulphonic acid, 5-sulpho- anthranilic acid, 2-naphthylamine-3,6,8-trisulphonic acid, bronner acid, metanilic acid and cleve acid with 4,7-dihydroxy-1,10-phenanthroline-2,9-dione. The dyes were characterized by elemental, IR and TLC analyses. Their dyeing performance as acid dyes has been assessed on viscose rayon, wool and cotton fibres.

  2. Mathematics in ancient Greece

    CERN Document Server

    Dantzig, Tobias

    2006-01-01

    More than a history of mathematics, this lively book traces mathematical ideas and processes to their sources, stressing the methods used by the masters of the ancient world. Author Tobias Dantzig portrays the human story behind mathematics, showing how flashes of insight in the minds of certain gifted individuals helped mathematics take enormous forward strides. Dantzig demonstrates how the Greeks organized their precursors' melange of geometric maxims into an elegantly abstract deductive system. He also explains the ways in which some of the famous mathematical brainteasers of antiquity led

  3. L’Entrepreneuriat au sein de la famille. Marchands et entrepreneurs en Inde Entrepreneurship in the Family Context: Merchants and Entrepreneurs in India

    Directory of Open Access Journals (Sweden)

    Harald Tambs-Lyche

    2013-06-01

    Full Text Available Malgré le déni de Max Weber, l’essor actuel de l’économie indienne montre que non seulement l’esprit du capitalisme, mais aussi l’entrepreneuriat, sont bien présents en Inde. Dans cet article, j’analyse les stratégies commerciales des Gauda Saraswat Brahmanes du Sud Kanara (autour de Mangalore, sur la côte Ouest de l’Inde, en utilisant le modèle d’entrepreneuriat proposé par Fredrik Barth (1962, 1967. Fidèle à la tradition du « capitalisme de portefeuille » (Baily 1989, ces marchands distribuent leur capital entre des filières sûres mais modérément rentables, et des projets novateurs et profitables mais risqués. L’entrepreneur, ici, n’est que rarement l’individu, car il s’agit le plus souvent d’une stratégie orchestrée par la famille, qui se confond à son tour avec la firme familiale. Cette orchestration exige des chefs de famille un souci constant de management qui se manifeste en écoutant les idées des cadets et en leur confiant des rôles qui les gratifient au sein de l’entreprise familiale, tout en gardant la main sur la stratégie globale de la firme.In spite of Max Weber’s views, the present growth in the Indian economy shows rather conclusively the presence both of the spirit of capitalism and of entrepreneurship in India. In this article, I analyse the commercial strategies of the Gauda Saraswat Brahmins of South Kanara (around Mangalore, on the West coast of India, using the model of entrepreneurship proposed by Fredrik Barth (1962, 1967. True to the tradition of portefeuille capitalism (Baily 1989, these merchants distribute their capital between safe but moderately remunerative ventures, and projects that are profitable but risky. The entrepreneur, here, is rarely an individual, rather we see a strategy orchestrated by the family, which in its turn corresponds to the family firm. This organisation demands constant attention from the head of the family, who must listen to the ideas of

  4. Synthesis and in vitro antimalarial activity of a series of bistriazine compounds / Marnitz Tobias Verwey.

    OpenAIRE

    Verwey, Marnitz Tobias

    2012-01-01

    Malaria persists to proliferate as an economic and social burden in the developing countries despite of a 17% decrease in the estimated number mortalities as reported by the World Health Organization in 2011. In the past decade the annually estimated number of malaria cases has never gone under 216 million, resulting in the mortality rate of more than 8,3 million people, 655 000 in 2011. This worldwide disease is endemic in 109 countries, is dominant in sub-Saharan Africa with 91% of reported...

  5. TU-G-210-02: TRANS-FUSIMO - An Integrative Approach to Model-Based Treatment Planning of Liver FUS

    Energy Technology Data Exchange (ETDEWEB)

    Preusser, T. [Fraunhofer MEVIS & Jacobs University (Germany)

    2015-06-15

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  6. TU-G-210-01: Modeling for Breast and Brain HIFU Treatment Planning

    International Nuclear Information System (INIS)

    Christensen, D.

    2015-01-01

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  7. TU-G-210-01: Modeling for Breast and Brain HIFU Treatment Planning

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, D. [University of Utah (United States)

    2015-06-15

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  8. TU-G-210-00: Treatment Planning Strategies, Modeling, Control

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  9. TU-G-210-02: TRANS-FUSIMO - An Integrative Approach to Model-Based Treatment Planning of Liver FUS

    International Nuclear Information System (INIS)

    Preusser, T.

    2015-01-01

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  10. TU-G-210-00: Treatment Planning Strategies, Modeling, Control

    International Nuclear Information System (INIS)

    2015-01-01

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  11. Human radiation studies: Remembering the early years. Oral history of Donner Lab Administrator Baird G. Whaley, August 15, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    Baird G. Whaley, Donner Lab Administrator, was interviewed by representatives of US DOE Office of Human Radiation Experiments (OHRE). The purpose of the interview was to capture the remembrances of Mr. Whaley concerning what he could relate on activities at the Donner Lab that pertain to the OHRE responsibilities. Following a brief biographical sketch, Mr. Whaley relates his experiences in administration at the LAB including funding activities, staffing concerns, intralaboraory politics, and remembrances of John Lawrence, John Gofman, Cornelius Tobias, Jim Born, Alex Margolis, B.V.A. Low- Beer, and Ed Alpen. Further patient care procedures for Donner Clinic Research Programs were discussed.

  12. Human radiation studies: Remembering the early years. Oral history of Donner Lab Administrator Baird G. Whaley, August 15, 1994

    International Nuclear Information System (INIS)

    1995-09-01

    Baird G. Whaley, Donner Lab Administrator, was interviewed by representatives of US DOE Office of Human Radiation Experiments (OHRE). The purpose of the interview was to capture the remembrances of Mr. Whaley concerning what he could relate on activities at the Donner Lab that pertain to the OHRE responsibilities. Following a brief biographical sketch, Mr. Whaley relates his experiences in administration at the LAB including funding activities, staffing concerns, intralaboraory politics, and remembrances of John Lawrence, John Gofman, Cornelius Tobias, Jim Born, Alex Margolis, B.V.A. Low- Beer, and Ed Alpen. Further patient care procedures for Donner Clinic Research Programs were discussed

  13. Studies on Synthesis and Dyeing Preformance of Acid Dyes Based on 4,7-Dihydroxy-3,8-di-α-naphthylazo-1,10-phenanthroline-2,9-Dione

    Directory of Open Access Journals (Sweden)

    B. V. Patel

    2007-01-01

    Full Text Available Some new azo acid dyes were prepared by coupling various diazotized acid components such as anthranilic acid, sulphanilic acid, laurentacid, peri acid, tobias acid, H-acid, J-acid, gamma acid, sulphotobias acid,4-aminotoluiene-3-sulphonic acid, 5-sulpho- anthranilic acid, 2-naphthylamine-3,6,8-trisulphonic acid, bronner acid, metanilic acid and cleve acid with 4,7-dihydroxy-3,8-di-α-naphthylazo-1,10-phenanthroline-2,9-dione. The dyes were characterized by elemental, IR and TLC analyses. Their dyeing performance as acid dyes has been assessed on viscose rayon, wool and cotton fibres.

  14. LIQUID-LIQUID EQUILIBRIA OF THE TERNARY SYSTEMS PROPIONIC ACID - WATER - SOLVENT (n-AMYL ALCOHOL AND n-AMYL ACETATE

    Directory of Open Access Journals (Sweden)

    Dilek ÖZMEN

    2005-02-01

    Full Text Available The experimental liquid-liquid equilibrium (LLE data have been obtained at 25 oC for ternary systems propionic acid-water-n-amyl alcohol and propionic acid-water-n-amyl acetate. The reliability of the experimental tie line data are checked using the methods of Othmer-Tobias and Hand. The distribution coefficients and separation factors were obtained from experimental results and are also reported. The predicted tie line data obtained by UNIFAC method are compared with experimental data. It is concluded that n-amyl alcohol and n-amyl acetate are suitable separating agents for dilute aqueous propionic acid solutions.

  15. Variation among early Homo crania from Olduvai Gorge and the Koobi Fora region.

    Science.gov (United States)

    Rightmire, G P

    1993-01-01

    Fossils recognized as early Homo were discovered first at Olduvai Gorge in 1959 and 1960. Teeth, skull parts and hand bones representing three individuals were found in Bed I, and more material followed from Bed I and lower Bed II. By 1964, L.S.B. Leakey, P.V. Tobias, and J.R. Napier were ready to name Homo habilis. But almost as soon as they had, there was confusion over the hypodigm of the new species. Tobias himself suggested that OH 13 resembles Homo erectus from Java, and he noted that OH 16 has teeth as large as those of Australopithecus. By the early 1970s, however, Tobias had put these thoughts behind him and returned to the opinion that all of the Olduvai remains are Homo habilis. At about this time, important discoveries began to flow from the Koobi Fora region in Kenya. To most observers, crania such as KNM-ER 1470 confirmed the presence of Homo in East Africa at an early date. Some of the other specimens were problematical. A.C. Walker and R.E. Leakey raised the possibility that larger skulls including KNM-ER 1470 differ significantly from smaller-brained, small-toothed individuals such as KNM-ER 1813. Other workers emphasized that there are differences of shape as well as size among the hominids from Koobi Fora. There is now substantial support for the view that in the Turkana and perhaps also in the Olduvai assemblages, there is more variation than would be expected among male and female conspecifics. One way to approach this question of sorting would be to compare all of the new fossils against the original material from Olduvai which was used to characterize Homo habilis in 1964. A problem is that the Olduvai remains are fragmentary, and none of them provides much information about vault form or facial structure. An alternative is to work first with the better crania, even if these are from other sites. I have elected to treat KNM-ER 1470 and KNM-ER 1813 as key individuals. Comparisons are based on discrete anatomy and measurements. Metric results

  16. Boundaries, Discrimination, and Interethnic Conflict in Xinjiang, China

    Directory of Open Access Journals (Sweden)

    Enze Han

    2010-12-01

    Full Text Available

    The Xinjiang Uighur Autonomous Region has been afflicted by Uighur political activism and ethnic violence for the past few decades. Interethnic relations between the Uighurs and Han Chinese have been extremely tense. Why is Xinjiang so vulnerable to interethnic violence? Why are intergroup
    dynamics between the Uighurs and Han Chinese so volatile? This paper examines Uighur–Han Chinese relations in contemporary Xinjiang and probes conditions that facilitate interethnic violence. Utilizing Fredrik Barth’s approach to ethnicity that emphasizes boundaries, this paper examines in detail how the rigid interethnic boundary between the Uighurs and Han Chinese has been constructed and strengthened in Xinjiang. Perceived differences have generated mutual distrust and discrimination between the two groups that make intergroup communication and understanding difficult and therefore very limited. In situations such as that in Xinjiang, where a rigid intergroup boundary is in place and civic engagements across groups are lacking, intergroup conflict is
    extremely hard to avoid.

  17. Book Reviews

    Directory of Open Access Journals (Sweden)

    James F. Weiner

    1988-10-01

    Full Text Available - A.P. Borsboom, Fredrik Barth, Cosmologies in the making; A generative approach to cultural variation in Inner New Guinea, Cambridge studies in social anthropology, Cambridge University Press, 1987, 99 pp., - H.J.M. Claessen, Paul van der Grijp, Sporen in de Antropologie; Liber Amicorum voor Jan Pouwer, Nijmegen: Instituut voor Kulturele en Sociale Antropologie, 1987. Bibl., tab., ill. 330 pp., Ton Lemaire, Albert Trouwborst (eds. - Simon Kooijman, Adrian Horridge, Outrigger canoes of Bali and Madura, Indonesia, Bishop museum special bulletin 77, Honolulu: Bishop museum press, 1987. xii + 178 pp., 4 maps, 1 colour photograph, 19 black and white photographs, 71 line drawings. - Jelle Miedema, D.K. Feil, The evolution of highland Papua New Guinea societies, Cambridge: University Press, 1987, xii + 313 pp. - Jelle Miedema, James F. Weiner, Mountain Papuans; Historical and comparitive perspectives from New Guinea fringe highlands societies. Ann Arbor: The University of Michigan Press, 1988, 230 pp. - Jetta Wille, Paulus M.F. van der Grijp, Produktie en denkwijzen in Polynesië; Sociale asymmetrie, ideologie en verandering op de Tonga-eilanden, Proefschrift Nijmegen, 1987.

  18. An assessment of fission product data for decay power calculation in fast reactors

    International Nuclear Information System (INIS)

    Sridharan, M.S.; Murthy, K.P.N.

    1987-01-01

    A review of our present capability at IGC, Kalpakkam to predict fission product decay power in fast reactors is presented. This is accomplished by comparing our summation calculations with the calculations of others and the reported experimental measurements. Our calculations are based on Chandy code developed at our Centre. The fission product data base of Chandy is essentially drawn from the yield data compiled by Crouch (1977) and the data on halflives etc. compiled by Tobias (1973). In general, we find good agreement amongst the different calculations (within ±5%) and our calculations also compare well with experimental measurements of AKIAMA et al and MURPHY et al

  19. Liquid-liquid equilibrium data in aqueous solutions of propionic and butyric acids with 1-heptanol at T=(298.15, 308.15, and 318.15) K

    Energy Technology Data Exchange (ETDEWEB)

    Gilani, Ali Ghanadzadeh; Gilani, Hossein Ghanadzadeh; Saadat, Seyedeh Laleh Seyed; Nasiri-Touli, Elham; Peer, Mahrokh [Faculty of Science, University of Guilan, Rasht (Iran, Islamic Republic of)

    2016-04-15

    Liquid-liquid phase equilibrium (LLE) data were determined for the (water+propionic or butyric acid+1- heptanol) ternary systems at T=(298.15, 308.15, and 318.15) K and p=101.3 kPa. For both systems, a type-1 LLE phase diagram was obtained. The quality of the experimental LLE data was determined through the Othmer-Tobias and Bancroft equations. The experimental tie-lines were fitted using the UNIQUAC and NRTL correlation models. For the studied systems, a comparison was made between the experimental and correlated distribution coefficients and separation factors. The LSER model of Katritzky was applied to obtain the contributions of intermolecular interactions in these systems.

  20. On Baltic Slovenia and Adriatic Lithuania. A qualitative comparative analysis of patterns in post-communist transformation / Lars Fredrik Stöcker

    Index Scriptorium Estoniae

    Stöcker, Lars Fredrik, 1979-

    2014-01-01

    Arvustus: Norkus, Zenonas. On Baltic Slovenia and Adriatic Lithuania. A qualitative comparative analysis of patterns in post-communist transformation. Verlag Apostrofia Publishers, Central European University Press. Budapest und New York 2012

  1. Colloquium: cavity optomechanics

    CERN Multimedia

    2011-01-01

    Monday 14 November 2011, 17:00 Ecole de Physique, Auditoire Stueckelberg Université de Genève Cavity optomechanics: controlling micro mechanical oscillators with laser light Prof. Tobias Kippenberg EPFL, Lausanne Laser light can be used to cool and to control trapped ions, atoms and molecules at the quantum level. This has lead to spectacular advances such as the most precise atomic clocks. An outstanding frontier is the control with lasers of nano- and micro-mechancial systems. Recent advances in cavity optomechanics have allowed such elementary control for the first time, enabling mechanical systems to be ground state cooled leading to readout with quantum limited sensitivity and permitting to explore new device concepts resulting from radiation pressure.  

  2. Review: Wilfried Breyvogel (Ed. (2005. Einführung in Jugendkulturen. Veganismus und Tattoos [Introduction to Youth Cultures. Veganism and Tattoos

    Directory of Open Access Journals (Sweden)

    Sebastian Schröer

    2007-09-01

    Full Text Available Wilfried BREYVOGEL's introductory textbook combines three individual texts. As well as an historic overview of diverse "youth cultures" there are two extensive contributions devoted to veganism (Thomas SCHWARZ and tattoos (Tobias LOBSTÄDT. BREYVOGEL's contribution is a literature-based study, whereas SCHWARZ and LOBSTÄDT present work based on original research. However, expectations of an introductory textbook are disappointed because the book does not contain a well-founded and "tight" theoretical derivation on the topic of "youth cultures," and the two choice of the two exemplary youth cultures makes little sense. Furthermore, the individual contributions show flaws in both content and format. URN: urn:nbn:de:0114-fqs0703279

  3. COMPOSITION OF THE JOINT ADVISORY APPEALS BOARDS 2000/2001 EXERCISE

    CERN Multimedia

    Human Resources Division

    2001-01-01

    Appointed by the Director-General  Appointed by the Staff Association Members Fréderick Bordry /sl Irene Seis/it 1st deputies Christian Fabjan/ep Jean-Claude Carlier/tis 2nd deputies Sue Foffano Morna Robillard/hr Mr Bordry and Mrs Seis have drawn up the following list of staff members from among whom the Chairman of the Board may be chosen when required: Christophe Delamare/est Guy Maurin/ep Maria Dimou/it Mats Moller/as Tobias Dobers/est Alasdair smith/ep Luc Durieu/ps Marilena Streit-Bianchi/tis Lennart Jirden/spl John Poole/sl Mediators [see Administrative Circular N° 6 (Rev. 1) entitled 'Review procedure'] will also be selected from this list of ten staff members.

  4. As armas dos fracos: estratégias, táticas e repercussões identitárias na dinâmica do acesso à saúde na fronteira Brasil/Paraguai

    Directory of Open Access Journals (Sweden)

    Valdir Aragão Nascimento

    Full Text Available Resumo O presente artigo objetiva expor e discutir algumas táticas e estratégias adotadas por paraguaios indocumentados para ter acesso à saúde por meio do SUS no Brasil. A pesquisa de campo realizou-se especificamente entre a cidade paraguaia de Pedro Juan Caballero e a cidade brasileira de Ponta Porã. Outro objetivo é discutir as relações socioculturais de caráter identitário que essas táticas e estratégias engendram e oportunizam na faixa de fronteira em questão. No tocante às táticas e estratégias, elencamos as concepções teóricas de Michel de Certeau a respeito dessas categorias. Fredrik Barth e seus conceitos atinentes aos grupos étnicos dão a tônica de nossa análise acerca das diversas, e por vezes divergentes, identidades étnicas oriundas das inter-relações estabelecidas na dinâmica que propicia a existência de táticas e estratégias – no tocante ao acesso à saúde – na fronteira do Brasil com o Paraguai.

  5. The uncanny, alienation and strangeness: the entwining of political and medical metaphor.

    Science.gov (United States)

    Edgar, Andrew

    2011-08-01

    This paper offers a critical response to Fredrik Svenaeus' use of the Heideggerian uncanny to analyse the experience of illness. It is argued that the uncanny is part of a culture of concepts through which the condition of modernity has been analysed by philosophers, social theorists, writers and artists. All centre upon the idea of alienation, and thus not being at home in the society that should be one's home. This association will be exploited to offer a reinterpretation of Svenaeus' thesis as a sociological and political, rather than an ontological, one. By reviewing the work of Hegelian philosophers, Georg Simmel, and novelists, represented by Mann, Camus and McCullers, it will be argued that illness is bound up with social alienation, both as something that is caused by conditions of alienation and as an interpretative response to alienation. Seeing illness as a metaphor of the human condition in modernity allows the medical humanities to inform therapy, that would allow the patient to understand their illness, not as the ontological condition of Dasein, but rather as something mediated by modern social, economic and political conditions.

  6. Online devices and measuring systems for the automatic control of newspaper printing

    Science.gov (United States)

    Marszalec, Elzbieta A.; Heikkila, Ismo; Juhola, Helene; Lehtonen, Tapio

    1999-09-01

    The paper reviews the state-of-the-art color measuring systems used for the control of newspaper printing. The printing process requirements are specified and different off-line and on-line color quality control systems, commercially available and under development, are evaluated. Recent market trends in newspaper printing are discussed based on the survey. The study was made on information derived from: conference proceedings (TAGA, IARIGAI, SPIE and IS&T), journals (American Printer, Applied Optics), discussions with experts (GMI, QTI, HONEYWELL, TOBIAS, GretagMacbeth), IFRA Expo'98/Quality Measuring Technologies, commercial brochures, and the Internet. On the background of this review, three different measuring principles, currently, under investigation at VTT Information Technology, are described and their applicability to newspaper printing is evaluated.

  7. Die Reichweite der Haftungsprivilegien nach dem SGB VII außerhalb des klassischen Arbeitsunfalls / Tobias Matz ; Claudia Baumann

    Index Scriptorium Estoniae

    Matz, Tobias

    2016-01-01

    Ettevõtte ja kollektiivi vastutusest sotsiaalseadustiku § 104 jj tähenduses ebatraditsiooniliste tööõnnetuste korral (nt koolides õpilaste/õpetajate vigastused; praktikandid kutseõppes; loomade tekitatud vigastused jms)

  8. Université de Genève | Séminaire de physique corpusculaire | 27 November

    CERN Multimedia

    2013-01-01

    Dans le cadre de la procédure de nomination d'un-e professeur-e associé-e ou assistant-e au DPNC,     le mercredi 27 novembre 2013 Auditoire 1S059 - Sciences III - Boulevard d’Yvoy   9h – 10h  Colloque du Dr Tobias Golling "Life after Higgs" 10h – 11h  Colloque Lucia Masetti "Searches for New Physics with top Quarks: a two-way approach" 11h – 12h  Colloque du Dr Krisztian Peters "Higgs Physics at the Energy Frontier"   Les résumés des différents colloques sont disponibles ici. Les membres du corps enseignant et les étudiants sont invités aux colloques et peuvent faire part de leurs commentaires au Doyen de la Faculté.

  9. ESTUDIO DEL EQUILIBRIO LÍQUIDO-LÍQUIDO DE BENCENO + (HEXANO, HEPTANO Y CICLOHEXANO CON EL LÍQUIDO IÓNICO 1-ETIL-3-METILIMIDAZOLIO ETILSULFATO A 308,15 K

    Directory of Open Access Journals (Sweden)

    Marlon Martínez Reina

    2011-12-01

    Full Text Available Se determinó el equilibrio líquido-líquido(ELL de los sistemas ternarios benceno+ (hexano, heptano y ciclohexanocon el líquido iónico 1-etil-3-metilimidazolioetilsulfato (EMIM-EtSO4 a 308,15K; la selectividad (S y el coeficiente dedistribución (β se calcularon desde losdatos experimentales que se utilizaronpara determinar la capacidad del líquidoiónico como solvente para la separacióndel aromático desde sus mezclas con hidrocarburosalifáticos. La región de inmiscibilidadaumentó en el siguiente orden:ciclohexano consistencia de los datos experimentalesdel ELL es evaluado usando la ecuaciónde Othmer-Tobias. La composición delas fases en equilibrio se correlacionócon los modelos para coeficientes de actividadNRTL y Uniquac.

  10. A new species of Megalommum Szépligeti (Hymenoptera, Braconidae, Braconinae); a parasitoid of the pistachio longhorn beetle (Calchaenesthes pistacivora Holzschuh; Coleoptera, Cerambycidae) in Iran

    Science.gov (United States)

    van Achterberg, C.; Mehrnejad, M.R.

    2011-01-01

    Abstract A new species of the genus Megalommum Szépligeti (Hymenoptera: Braconidae: Braconinae), reared from the pistachio longhorn beetle (Calchaenesthes pistacivora Holzschuh; Coleoptera: Cerambycidae), is described and illustrated. The genera Curreia Ashmead, 1900 and Endovipio Turner, 1922 are new synonyms of Megalommum Szépligeti, 1900. Notes on the biology of Megalommum pistacivorae sp. n. and a key to the West Palaearctic and Oriental species are added. The following new combinations are given: Megalommum xanthoceps (Fahringer, 1928), comb. n., Megalommum jacobsoni (Tobias, 1968), comb. n., Megalommum ayyari (Watanabe, 1950), comb. n., Megalommum philippinense (Baker, 1917), comb. n., Megalommum dodecanesi(Ferrière, 1922), comb. n., Megalommum ceresense (Turner, 1922), comb. n., Megalommum inareatum (Granger, 1949), comb. n., Megalommum antefurcale (Szépligeti, 1915) comb. n. and Megalommum tibiale (Ashmead, 1906), comb. n. PMID:21976987

  11. Separation of benzene from alkanes by solvent extraction with 1-ethylpyridinium ethylsulfate ionic liquid

    International Nuclear Information System (INIS)

    Gomez, Elena; Dominguez, Irene; Calvar, Noelia; Dominguez, Angeles

    2010-01-01

    The (liquid + liquid) equilibrium (LLE) data for ternary mixtures {alkane + benzene + 1-ethylpyridinium ethylsulfate ([EPy][EtSO 4 ])} at T = (283.15 and 298.15) K and atmospheric pressure are presented. The alkanes used were hexane and heptane. The cloud point method was used to determinate the binodal curve, and the tie-line compositions were obtained by density measurements. The LLE data obtained were used to calculate distribution coefficients and selectivity values. The consistency of tie-line data was ascertained by applying the Othmer-Tobias and Hand equations. Correlation of the experimental tie-lines was conducted through the use of NRTL equation, which provides good correlation of the experimental data. The results show that [EPy][EtSO 4 ] can be used as an alternative solvent in liquid extraction processes for the removal of benzene from its mixtures with alkanes.

  12. Trained to battle cancer with particles

    CERN Multimedia

    2009-01-01

    The successful treatment of tumours with hadrons – hadron therapy – is only possible when accelerator experts, physicists, biologists and oncologists combine their efforts and share their expertises. The PARTNER project aims at training young students to become the future leaders in this field. Four of them are affiliated to CERN as fellows. The four CERN students participating in the PARTNER project. From left to right: Daniel Abler (Germany), Faustin Laurentiu Roman (Romania), Vassiliki Kanellopoulos (Greece/Germany) and Till Tobias Boehlen (Germany). Students attending the first course organised in June 2009 by the PARTNER Network in Valencia, Spain.Till (Germany), Faustin (Romania), Vassiliki (Greece/Germany) and Daniel (Germany) are the four PhD students based at CERN and working for PARTNER – a Marie Curie programme funded by the European Commission over four years. Its main goal is t...

  13. (Liquid + liquid) equilibria of aqueous solutions of butyric acid with n-heptane and toluene at T = (298.2, 308.2, and 318.2) K

    International Nuclear Information System (INIS)

    Ghanadzadeh Gilani, H.; Ghanadzadeh Gilani, A.; Janbaz, M.

    2013-01-01

    Highlights: ► Liquid equilibrium data of (water + butyric acid + n-heptane) were obtained. ► LLE data were correlated with NRTL and UNIQUAC models. ► Distribution coefficients and separation factors were evaluated. - Abstract: Solubility and tie line data for the (water + butyric acid + n-heptane) and (water + butyric acid + toluene) ternary systems were determined at T = (298.2, 308.2, and 318.2) K and atmospheric pressure. Solubility data were obtained by the cloud-point titration method. The concentration of each phase was determined by acidimetric titration, the Karl-Fischer technique, and refractive index measurements. The experimental tie-line data were correlated using the UNIQUAC and NRTL thermodynamic models. The reliability of the experimental data was determined through the Othmer–Tobias and Hand plots. Distribution coefficients and separation factors were evaluated for each system over the immiscibility regions.

  14. Nickel: makes stainless steel strong

    Science.gov (United States)

    Boland, Maeve A.

    2012-01-01

    Nickel is a silvery-white metal that is used mainly to make stainless steel and other alloys stronger and better able to withstand extreme temperatures and corrosive environments. Nickel was first identified as a unique element in 1751 by Baron Axel Fredrik Cronstedt, a Swedish mineralogist and chemist. He originally called the element kupfernickel because it was found in rock that looked like copper (kupfer) ore and because miners thought that "bad spirits" (nickel) in the rock were making it difficult for them to extract copper from it. Approximately 80 percent of the primary (not recycled) nickel consumed in the United States in 2011 was used in alloys, such as stainless steel and superalloys. Because nickel increases an alloy's resistance to corrosion and its ability to withstand extreme temperatures, equipment and parts made of nickel-bearing alloys are often used in harsh environments, such as those in chemical plants, petroleum refineries, jet engines, power generation facilities, and offshore installations. Medical equipment, cookware, and cutlery are often made of stainless steel because it is easy to clean and sterilize. All U.S. circulating coins except the penny are made of alloys that contain nickel. Nickel alloys are increasingly being used in making rechargeable batteries for portable computers, power tools, and hybrid and electric vehicles. Nickel is also plated onto such items as bathroom fixtures to reduce corrosion and provide an attractive finish.

  15. PREFACE: PASREG 2003: International Workshop on Processing and Applications of Superconducting (RE)BCO Large Grain Materials

    Science.gov (United States)

    Murakami, Masato; Cardwell, David; Salama, Kamel; Krabbes, Gernot; Habisreuther, Tobias; Gawalek, Wolfgang

    2005-02-01

    Superconducting melt-textured bulk (RE)BCO large grain materials are one of the most promising materials for power applications of high temperature superconductivity at the liquid nitrogen temperature range. Industrial applications are expected in high-speed low-loss magnetic bearings for flywheel energy storage devices, high-dynamic high-torque electric reluctance motors, and MAGLEV transportation systems. The material has high magnetic field trapping capability and therefore a new class of high-field superconducting permanent magnets will soon appear. However, there is still the need to improve the magnetic and mechanical material properties, as well as to increase the single domain size. This special issue contains papers concerning these topics presented at the International Workshop on the Processing and Applications of Superconducting (RE)BCO Large Grain Materials. The workshop was held on the 30 June-2 July 2003 in Jena, Germany, and was organized by the Institut fuer Physikalische Hochtechnologie, Jena. It was the fourth in the series of PASREG workshops after Cambridge, UK (1997), Morioka, Japan (1999), and Seattle, USA (2001). Sixty two contributions were presented at the workshop, 38 oral presentations and 24 poster presentations. This special issue contains 42 papers. The editors are grateful for the support of many colleagues who reviewed the manuscripts to guarantee their high technical quality. The editors also wish to thank Doris Litzkendorf and Tobias Habisreuther from Institut fuer Physikalische Hochtechnologie, Jena, for their assistance with the organization and handling of the manuscripts. Many thanks to the workshop co-chairman Gernot Krabbes from Leibniz-Institut fuer Festkoerper und Werkstoffforschung, Dresden, for hosting the workshop participants in Dresden. Finally, all attendees wish to acknowledge the efforts of Wolfgang Gawalek, Tobias Habisreuther, Doris Litzkendorf and the Team of Department Magnetics from the Institut fuer

  16. PREFACE: The 395th Wilhelm and Else Heraeus Seminar: `Time-dependent phenomena in Quantum Mechanics'

    Science.gov (United States)

    Kleber, Manfred; Kramer, Tobias

    2008-03-01

    The 395th Wilhelm and Else Heraeus Seminar: `Time-dependent phenomena in Quantum Mechanics' took place at the Heinrich Fabri Institute in Blaubeuren, Germany, 12-16 September 2007. The conference covered a wide range of topics connected with time-dependent phenomena in quantum mechanical systems. The 20 invited talks and 15 short talks with posters at the workshop covered the historical debate between Schrödinger, Dirac and Pauli about the role of time in Quantum Mechanics (the debate was carried out sometimes in footnotes) up to the almost direct observation of electron dynamics on the attosecond time-scale. Semiclassical methods, time-delay, monodromy, variational principles and quasi-resonances are just some of the themes which are discussed in more detail in the papers. Time-dependent methods also shed new light on energy-dependent systems, where the detour of studying the time-evolution of a quantum states allows one to solve previously intractable problems. Additional information is available at the conference webpage http://www.quantumdynamics.de The organizer would like to thank all speakers, contributors, session chairs and referees for their efforts in making the conference a success. We also gratefully acknowledge the generous financial support from the Wilhelm and Else Heraeus Foundation for the conference and the production of this special volume of Journal of Physics: Conference Series. Manfred Kleber Physik Department T30, Technische Universität München, 85747 Garching, Germany mkleber@ph.tum.de Tobias Kramer Institut I: Theoretische Physik, Universität Regensburg, 93040 Regensburg, Germany tobias.kramer@physik.uni-regensburg.de Guest Editors Front row (from left): W Schleich, E J Heller, J B Delos, H Friedrich, K Richter, M Kleber, P Kramer, M Man'ko, A del Campo, V Man'ko, M Efremov, A Ruiz, M O Scully Middle row: A Zamora, R Aganoglu, T Kramer, J Eiglsperger, H Cruz, P Raab, I Cirac, G Muga, J Larson, V Dodonov, W Becker Back row: A Eckardt, A

  17. (Liquid + liquid) equilibria for ternary mixtures of (water + propionic acid + organic solvent) at T = 303.2 K

    International Nuclear Information System (INIS)

    Ghanadzadeh, H.; Ghanadzadeh Gilani, A.; Bahrpaima, Kh.; Sariri, R.

    2010-01-01

    Experimental tie-line results and phase diagrams were obtained for the ternary systems of {water + propionic acid + organic solvent (cyclohexane, toluene, and methylcyclohexane)} at T = 303.2 K and atmospheric pressure. The organic solvents were two cycloaliphatic hydrocarbons (i.e., cyclohexane and methylcyclohexane) and an aromatic hydrocarbon (toluene). The experimental tie-lines values were also compared with those calculated by the UNIQUAC and NRTL models. The consistency of the values of the experimental tie-lines was determined through the Othmer-Tobias and Hands plots. Distribution coefficients and separation factors were evaluated over the immiscibility regions and a comparison of the extracting capabilities of the solvents was made with respect to distribution coefficients and separation factors. The Kamlet LSER model was applied to correlate distribution coefficients and separation factors in these ternary systems. The LSER model values showed a good regression to the experimental results.

  18. Summary of Session 7 'After Long Shutdown 1'

    International Nuclear Information System (INIS)

    Pojer, M; Schmidt, R

    2012-01-01

    After LS1 the energy will be about 6.5 TeV. The physics potential of LHC is determined by the integrated luminosity useful for the experiments and not only by the peak luminosity. The integrated luminosity is determined by the peak luminosity, the luminosity decay and the efficiency of operation (availability). In this session two of these parameters are addressed, the peak luminosity and the availability. Presentations related to peak luminosity: • Performance potential of the injectors after LS1, Heiko Damerau; • Performance reach of LHC after LS1, Werner Herr. Presentations related to availability: • Magnet powering with zero downtime - a dream? Markus Zerlauth; • Beam systems without failures – what can be done? Matteo Solfaroli and Jan Uythoven; • Will we still see SEEs? Marco Calviani; • UFOs – will they take over? Tobias Baer; • Quenches: will there be any? Arjan Verweij

  19. Separation of toluene from alkanes using 1-ethyl-3-methylpyridinium ethylsulfate ionic liquid at T = 298.15 K and atmospheric pressure

    International Nuclear Information System (INIS)

    Gonzalez, Emilio J.; Calvar, Noelia; Gonzalez, Begona; Dominguez, Angeles

    2010-01-01

    In this paper, the separation of toluene from aliphatic hydrocarbons (heptane, or octane, or nonane) was analyzed by solvent extraction with 1-ethyl-3-methylpyridinium ethylsulfate ionic liquid, [EMpy][ESO 4 ]. Liquid-liquid equilibrium (LLE) data for the ternary systems {heptane (1) + toluene (2) + [EMpy][ESO 4 ] (3)}, {octane (1) + toluene (2) + [EMpy][ESO 4 ] (3)}, and {nonane (1) + toluene (2) + [EMpy][ESO 4 ] (3)} were obtained by measurements at T = 298.15 K and atmospheric pressure. The selectivity, % removal of aromatic, and solute distribution ratio, obtained from experimental equilibrium results, were used to determine the ability of [EMpy][ESO 4 ] as a solvent. The degree of consistency of the experimental LLE values was ascertained using the Othmer-Tobias and Hand equations. The experimental results for the ternary systems were correlated with the NRTL model. Finally, the results obtained were compared with other ionic liquids and other solvents.

  20. Summary of Session 7 'After Long Shutdown 1'

    Energy Technology Data Exchange (ETDEWEB)

    Pojer, M; Schmidt, R [European Organization for Nuclear Research, Geneva (Switzerland)

    2012-07-01

    After LS1 the energy will be about 6.5 TeV. The physics potential of LHC is determined by the integrated luminosity useful for the experiments and not only by the peak luminosity. The integrated luminosity is determined by the peak luminosity, the luminosity decay and the efficiency of operation (availability). In this session two of these parameters are addressed, the peak luminosity and the availability. Presentations related to peak luminosity: • Performance potential of the injectors after LS1, Heiko Damerau; • Performance reach of LHC after LS1, Werner Herr. Presentations related to availability: • Magnet powering with zero downtime - a dream? Markus Zerlauth; • Beam systems without failures – what can be done? Matteo Solfaroli and Jan Uythoven; • Will we still see SEEs? Marco Calviani; • UFOs – will they take over? Tobias Baer; • Quenches: will there be any? Arjan Verweij.

  1. (Liquid + liquid) equilibrium data of (water + phosphoric acid + solvents) systems at T = (308.2 and 318.2) K

    International Nuclear Information System (INIS)

    Ghanadzadeh Gilani, H.; Ghanadzadeh Gilani, A.; Shekarsaraee, S.; Uslu, H.

    2012-01-01

    Highlights: ► Phase equilibria of the (water + PA + solvents) systems were investigated. ► Experimental LLE data were correlated with NRTL and UNIQUAC models. ► Distribution coefficients and separation factors were evaluated. - Abstract: Ternary equilibrium data for the mixtures of {water + phosphoric acid + organic solvent (cyclohexane, methylcyclohexane, and toluene)} were determined at T = (308.2 and 318.2) K and atmospheric pressure. Solubility data were determined by the cloud-point titration method. In order to obtain the tie-line data, the concentration of each phase was determined by acidimetric titration, the Karl–Fischer technique, and refractive index measurements. The experimental tie-line data were correlated using the UNIQUAC and NRTL models. The reliability of the experimental data was determined through the Othmer–Tobias and Hand plots. Distribution coefficients and separation factors were evaluated over the immiscibility regions. The Katritzky LSER model was applied to correlate distribution coefficients and separation factors in these ternary systems.

  2. Determinação eletroquímica do pesticida parationa metílica em águas de reservatório por voltametria de redissolução catódica

    Directory of Open Access Journals (Sweden)

    Silvanito A. Barbosa

    2011-12-01

    Full Text Available Methyl parathion is an organophosphorus compound widely used in Brazilian agriculture as antifouling agent. Given its importance, this paper presents the development and application of an electrochemical method for determination of the compound in natural waters. Results obtained during an initial optimization stage demonstrated the suitability of the technique for trace analysis, with limits of detection and quantification of 1.3 µg L-1 and 4.3 µg L-1, respectively. Samples were collected from the Jabiberi River (Tobias Barreto, State of Sergipe and were shown to contain methyl parathion concentrations of 96.9 µg L-1 (location 1 and 34.7 µg L-1 (location 2. These measurements are indicative of levels of contamination above those permitted by Brazilian legislation (CONAMA. Hence, in addition to assisting in the validation of the electroanalytical method as a tool for pesticide analysis, the results highlight the need for regulation and control of pesticide levels in natural waters.

  3. Critique of the War Reason

    DEFF Research Database (Denmark)

    Harste, Gorm

    was soldier and prisoner of war from age 15-17, would not write a “Der Krieg der Gesellschaft”. Yet the attempt to narrow this lacuna is indeed a heavy burden and a difficult task, in which, firstly, it is methodologically decisive to get the basic distinctions right about a second order observation of war......, and in social theory and sociology as well, there is a missing link in the lack of a sociology of war. A number of German systems theoreticians use Luhmann’s theory to fulfil that gap (Gertrud Brücher; Krysztof Matuszek; Rasmus Beckmann; Barbara Kuchler; Tobias Kohl; Klaus Dammann) Luhmann (born 1927), who...... as a conflict system – to be distinct from a military organisational system. This, I do initially with a reconceptualization of Carl von Clausewitz’ form analysis and self-description of war from Vom Kriege (1832). The central point, then, is to observe the self-reference of war, or how war became war about war...

  4. Далекое прошлое Эстонии / Адельберт Пооль

    Index Scriptorium Estoniae

    Пооль, Адельберт

    2008-01-01

    Eesti ajaloost ja kultuuritegelastest: 11. dets. (Narva), 15. dets. (Tallinn), 31. dets.; 2008: 8. jaan., 12.-15. jaan. (Eesti lipp ja hümn), 19.-22. jaan. (Eesti rahvussümbolid), 2.-5. veebr. (A. H. Tammsaare), 9. veebr. (O. W. Masing), 12. veebr. (K. J. Peterson), 16. veebr. (F. R. Faehlmann), 23. veebr. (K. Päts), 26. veebr. (F. R. Kreutzwald), 1. märts (J. V. Jannsen), 18. märts (J. Hurt), 1. apr. (K. R. Jakobson), 8. apr. (M. Veske), 12. apr. (A. Adamson), 15. apr. (E. Toll), 19. apr. (Toila Oru loss), 10. juuni (Kadriorg), 21. juuni (J. Mihkelson), 01. juuli (F. Bellingshausen), 5. juuli (O. von Kotzebue), 08. juuli (K. E. von Baer), 15. juuli (F. Wrangel), 19. juuli (E. Lents), 22. juuli (J. Köler), 26. juuli (A. Laikmaa, R. Tobias), 9. aug. (admiral S. Greig), 12. aug. (S. Julajev), 16. aug. (M. Barclay de Tolly), 19. aug. (F. G. V. Struve), 30. aug. (Nikolai Pirogov)

  5. Noise temperature improvement for magnetic fusion plasma millimeter wave imaging systems

    Energy Technology Data Exchange (ETDEWEB)

    Lai, J.; Domier, C. W.; Luhmann, N. C. [Department of Electrical and Computer Engineering, University of California at Davis, Davis, California 95616 (United States)

    2014-03-15

    Significant progress has been made in the imaging and visualization of magnetohydrodynamic and microturbulence phenomena in magnetic fusion plasmas [B. Tobias et al., Plasma Fusion Res. 6, 2106042 (2011)]. Of particular importance have been microwave electron cyclotron emission imaging and microwave imaging reflectometry systems for imaging T{sub e} and n{sub e} fluctuations. These instruments have employed heterodyne receiver arrays with Schottky diode mixer elements directly connected to individual antennas. Consequently, the noise temperature has been strongly determined by the conversion loss with typical noise temperatures of ∼60 000 K. However, this can be significantly improved by making use of recent advances in Monolithic Microwave Integrated Circuit chip low noise amplifiers to insert a pre-amplifier in front of the Schottky diode mixer element. In a proof-of-principle design at V-Band (50–75 GHz), significant improvement of noise temperature from the current 60 000 K to measured 4000 K has been obtained.

  6. Noise temperature improvement for magnetic fusion plasma millimeter wave imaging systems.

    Science.gov (United States)

    Lai, J; Domier, C W; Luhmann, N C

    2014-03-01

    Significant progress has been made in the imaging and visualization of magnetohydrodynamic and microturbulence phenomena in magnetic fusion plasmas [B. Tobias et al., Plasma Fusion Res. 6, 2106042 (2011)]. Of particular importance have been microwave electron cyclotron emission imaging and microwave imaging reflectometry systems for imaging T(e) and n(e) fluctuations. These instruments have employed heterodyne receiver arrays with Schottky diode mixer elements directly connected to individual antennas. Consequently, the noise temperature has been strongly determined by the conversion loss with typical noise temperatures of ~60,000 K. However, this can be significantly improved by making use of recent advances in Monolithic Microwave Integrated Circuit chip low noise amplifiers to insert a pre-amplifier in front of the Schottky diode mixer element. In a proof-of-principle design at V-Band (50-75 GHz), significant improvement of noise temperature from the current 60,000 K to measured 4000 K has been obtained.

  7. Noise temperature improvement for magnetic fusion plasma millimeter wave imaging systems

    International Nuclear Information System (INIS)

    Lai, J.; Domier, C. W.; Luhmann, N. C.

    2014-01-01

    Significant progress has been made in the imaging and visualization of magnetohydrodynamic and microturbulence phenomena in magnetic fusion plasmas [B. Tobias et al., Plasma Fusion Res. 6, 2106042 (2011)]. Of particular importance have been microwave electron cyclotron emission imaging and microwave imaging reflectometry systems for imaging T e and n e fluctuations. These instruments have employed heterodyne receiver arrays with Schottky diode mixer elements directly connected to individual antennas. Consequently, the noise temperature has been strongly determined by the conversion loss with typical noise temperatures of ∼60 000 K. However, this can be significantly improved by making use of recent advances in Monolithic Microwave Integrated Circuit chip low noise amplifiers to insert a pre-amplifier in front of the Schottky diode mixer element. In a proof-of-principle design at V-Band (50–75 GHz), significant improvement of noise temperature from the current 60 000 K to measured 4000 K has been obtained

  8. Energy technology of tomorrow. Strategies and concepts. Conference contributions; Energietechnik von morgen. Strategien und Konzepte. Konferenzbeitraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    Within the meeting 'Energy technology of tomorrow - Strategies and concepts' at 12th June, 2007 in Nuremberg (Federal Republic of Germany) the following lectures were held: (1) Cluster energy technology (Klaus Hassmann); (2) Dimension of future energy supply - prognoses/strategies/concepts (Ludger Mohrbach); (3) Future technologies for a CO{sub 2} reduced energy supply (Helmut Tschaffon); (4) Energy research - New specific targets and results (Hartmut Spliethoff); (5) Technological progress for future power plants at RWE (Frank Schwending); (6) Future potential of the generation of syngas with different energy sources (Sebastian Muschelknautz); (7) Innovations in plant engineering - on the way to a CO{sub 2} free power plant (Tobias Jockenhoevel); (8) Solar thermal power plants - status and prospects (Robert Piltz-Paal); (9) Perspectives of the generation of liquid hydrocarbons using nuclear energy (Kurt Kugeler); (10) Application of the MPG gasification technology in the refining of Canadian tar sands (Matthias Mueller-Hagedorn); (11) Perspectives for a sustainable supply with energy carriers (Ulrich Balfanz).

  9. Geneva Marathon

    CERN Document Server

    CERN Running and Fitness Clubs

    2010-01-01

    Congratulations to all the CERN participants in the Geneva marathon and half-marathon who ran on Sunday 9 May. CERN performed exceptionally well in the inter-enterprise category, collecting the 1st and 2nd places in the Marathon competition, and 2nd place in the half-marathon competition.   Some of the CERN Running Club participants after the Geneva Marathon 2010. From left to right: Junginger Tobias (marathon), Dore Graham (half-marathon), Cauphy Alain (marathon), Ruiz Camille (half-marathon), Ziogas Nicolas (marathon), Fluckiger Martin (marathon). More than 24 runners from CERN participated in either the Marathon or the half-Marathon. A successful but not easy day in Geneva, as reported by Nick Ziogas: “37 to 40 was very tough for me. My goal was to improve from last year and I improved by 3 minutes 10 seconds which is fantastic really. So I am delighted!”. Participants in the leading CERN teams in each category are listed below. MARATHON 1. CERN ...

  10. "Man müsse keine Statue Equestre machen": Abildgaard and Schadow in Copenhagen 1791

    Directory of Open Access Journals (Sweden)

    Kragelund, Patrick

    2011-03-01

    Full Text Available In connection with the project of erecting an equestrian statue for King Frederick the Great of Prussia, the Berlin sculptor Johann Gottfried Schadow was in the autumn 1791 sent on a research tour to the three Baltic capitals, Stockholm, St. Petersburg and Copenhagen. Here he studied and discussed similar recent projects with fellow artists, and brought reports back to Berlin on the equestrian statues by Pierre Hubert L'Archevêque and Johan Tobias Sergel (Gustavus Adolphus in Stockholm, by Étienne Maurice Falconet (Peter the Great in St. Petersburg and by Jacques François Joseph Saly (Frederick V in Copenhagen. Documents not previously published throw new light on the contacts Schadow during these travels established with the Danish painter Nicolai Abildgaard, a contact, it is here argued, that strengthened Schadow's commitment to use a historically accurate, more realistic and less idealised stylistic idiom when depicting great figures from the national past.

  11. Tobias Endler.  After 9/11:  Leading Political Thinkers about the World, the U.S. and Themselves, 17 Conversations.  

    Directory of Open Access Journals (Sweden)

    Joseph Michale Gratale

    2011-09-01

    Full Text Available This September marks ten years since the 9/11 terrorist attack against the U.S. back in 2001.  It is hard to believe that a decade has passed already; the images from that day seem so current, perhaps a result of their emotional resonance or constant reproduction and circulation in the world’s mediascapes.  For many, 9/11 was a watershed event which has defined the beginning of the twenty-first century, providing a political-ideological context from which to make sense of a world that had bee...

  12. Sorafenib inhibits tumor growth and vascularization of rhabdomyosarcoma cells by blocking IGF-1R-mediated signaling

    Directory of Open Access Journals (Sweden)

    Wessen Maruwge

    2008-11-01

    Full Text Available Wessen Maruwge1, Pádraig D’Arcy1, Annika Folin1,2, Slavica Brnjic1, Johan Wejde1, Anthony Davis1, Fredrik Erlandsson3, Jonas Bergh1,2, Bertha Brodin11Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden; 2Radiumhemmet, Karolinska University Hospital, Stockholm, Sweden; 3Bayer Pharmaceutical Corporation, SwedenAbstract: The growth of many soft tissue sarcomas is dependent on aberrant growth factor signaling, which promotes their proliferation and motility. With this in mind, we evaluated the effect of sorafenib, a receptor tyrosine kinase inhibitor, on cell growth and apoptosis in sarcoma cell lines of various histological subtypes. We found that sorafenib effectively inhibited cell proliferation in rhabdomyosarcoma, synovial sarcoma and Ewing’s sarcoma with IC50 values <5 µM. Sorafenib effectively induced growth arrest in rhabdomyosarcoma cells, which was concurrent with inhibition of Akt and Erk signaling. Studies of ligand-induced phosphorylation of Erk and Akt in rhabdomyosarcoma cells showed that insulin-like growth factor-1 is a potent activator, which can be blocked by treatment with sorafenib. In vivo sorafenib treatment of rhabdomyosarcoma xenografts had a significant inhibitory effect on tumor growth, which was associated with inhibited vascularization and enhanced necrosis in the adjacent tumor stroma. Our results demonstrate that in vitro and in vivo growth of rhabdomyosarcoma can be suppressed by treatment with sorafenib, and suggests the possibilities of using sorafenib as a potential adjuvant therapy for the treatment of rhabdomyosarcoma.Keywords: soft tissue sarcoma, kinase inhibitors, targeted therapy, vascularization

  13. Comparing patients with spinal cord infarction and cerebral infarction: clinical characteristics, and short-term outcome

    Directory of Open Access Journals (Sweden)

    Naess H

    2011-08-01

    Full Text Available Halvor Naess, Fredrik RomiDepartment of Neurology, Haukeland University Hospital, N-5021 Bergen, NorwayBackground: To compare the clinical characteristics, and short-term outcome of spinal cord infarction and cerebral infarction.Methods: Risk factors, concomitant diseases, neurological deficits on admission, and short-term outcome were registered among 28 patients with spinal cord infarction and 1075 patients with cerebral infarction admitted to the Department of Neurology, Haukeland University Hospital, Bergen, Norway. Multivariate analyses were performed with location of stroke (cord or brain, neurological deficits on admission, and short-term outcome (both Barthel Index [BI] 1 week after symptom onset and discharge home or to other institution as dependent variables.Results: Multivariate analysis showed that patients with spinal cord infarction were younger, more often female, and less afflicted by hypertension and cardiac disease than patients with cerebral infarction. Functional score (BI was lower among patients with spinal cord infarctions 1 week after onset of symptoms (P < 0.001. Odds ratio for being discharged home was 5.5 for patients with spinal cord infarction compared to cerebral infarction after adjusting for BI scored 1 week after onset (P = 0.019.Conclusion: Patients with spinal cord infarction have a risk factor profile that differs significantly from that of patients with cerebral infarction, although there are some parallels to cerebral infarction caused by atherosclerosis. Patients with spinal cord infarction were more likely to be discharged home when adjusting for early functional level on multivariate analysis.Keywords: spinal cord infarction, cerebral infarction, risk factors, short-term outcome

  14. „Keine Krankheit im üblichen Sinne“ – Männliche Homosexualität im Blickfeld des Bundestags, 1968–1982

    Directory of Open Access Journals (Sweden)

    Tobias Jakobi

    2014-12-01

    Full Text Available Tobias Jakobi concerns himself with the Bundestag’s view on male homosexuality during the 1970s in his article „Keine Krankheit im üblichen Sinne (not a desease in the usual sense“. His goal is to carve out a so called thread of discourse, which may serve as a link to further deepening of the topic within a broader context of discourse studies. The utilized sources are printed papers (Drucksachen and logs of plenary meetings (Plenarprotokolle. His enquiry focuses on four main topics: First, the Bundestag’s dealing with the liberalisation of paragraph 175 StGB. Second, the political discussions concerning pornography and the question, whether homosexuality can be regarded as pathological. Third, the Bundeswehr's way of dealing with homosexuality, and fourth, the questions concerning the prosecution of homosexuals during the so called Third Reich and the linked question, whether homosexuals should receive compensation. Jakobi shows that even though homosexuality was further decriminalised and depathologised during the 70s, no radical changes within society and therefore no normalisation of homosexuality took place.

  15. Separation of toluene and heptane by liquid-liquid extraction using z-methyl-N-butylpyridinium tetrafluoroborate isomers (z = 2, 3, or 4) at T = 313.2 K

    International Nuclear Information System (INIS)

    Garcia, Julian; Garcia, Silvia; Torrecilla, Jose S.; Oliet, Mercedes; Rodriguez, Francisco

    2010-01-01

    The (liquid + liquid) equilibrium (LLE) data for three ternary systems containing heptane, toluene, and a z-methyl-N-butylpyridinium tetrafluoroborate ionic liquid ([zbmpy][BF 4 ] IL, where z = 2, 3, or 4) were determined at T = 313.2 K and atmospheric pressure. The effect of IL cation isomers on the LLE data was evaluated for the first time. The selectivity and extractive capacity from these LLE data were calculated and compared to those previously reported in the literature for the systems (heptane + toluene + [4bmpy][BF 4 ]) and (heptane + toluene + sulfolane). The results show that the LLE data for the systems comprising the ILs with the metha- and para-substituted cations do not differ significantly from isomer to isomer. On the other hand, significant differences were observed among the systems with the ortho-substituted cation and the other two cation isomers. The degree of consistency of the experimental LLE data was ascertained by applying the Othmer-Tobias correlation. In addition, the LLE data were satisfactorily correlated by means of the thermodynamic NRTL model.

  16. Electron Transport Properties of Ge nanowires

    Science.gov (United States)

    Hanrath, Tobias; Khondaker, Saiful I.; Yao, Zhen; Korgel, Brian A.

    2003-03-01

    Electron Transport Properties of Ge nanowires Tobias Hanrath*, Saiful I. Khondaker, Zhen Yao, Brian A. Korgel* *Dept. of Chemical Engineering, Dept. of Physics, Texas Materials Institute, and Center for Nano- and Molecular Science and Technology University of Texas at Austin, Austin, Texas 78712-1062 e-mail: korgel@mail.che.utexas.edu Germanium (Ge) nanowires with diameters ranging from 6 to 50 nm and several micrometer in length were grown via a supercritical fluid-liquid-solid synthesis. Parallel electron energy loss spectroscopy (PEELS) was employed to study the band structure and electron density in the Ge nanowires. The observed increase in plasmon peak energy and peak width with decreasing nanowire diameter is attributed to quantum confinement effects. For electrical characterization, Ge nanowires were deposited onto a patterned Si/SiO2 substrate. E-beam lithography was then used to form electrode contacts to individual nanowires. The influence of nanowire diameter, surface chemistry and crystallographic defects on electron transport properties were investigated and the comparison of Ge nanowire conductivity with respect to bulk, intrinsic Ge will be presented.

  17. (Liquid + liquid) equilibrium data for the ternary systems (cycloalkane + ethylbenzene + 1-ethyl-3-methylimidazolim ethylsulfate) at T = 298.15 K and atmospheric pressure

    International Nuclear Information System (INIS)

    Gonzalez, Emilio J.; Calvar, Noelia; Dominguez, Irene; Dominguez, Angeles

    2011-01-01

    Research highlights: → [EMim][ESO 4 ] was studied as solvent to extract ethylbenzene from cycloalkanes. → (Liquid + liquid) equilibrium data were measured at 298.15K and atmospheric pressure. → Selectivity and solute distribution ratio were obtained and compared with literature. → Experimental data were satisfactorily correlated using NRTL and UNIQUAC models. → [EMim][ESO 4 ] can be used as solvent for the studied (liquid + liquid) extraction. - Abstract: In this paper, (liquid + liquid) equilibrium (LLE) data for the ternary systems (cyclohexane, or cyclooctane, or methylcyclohexane + ethylbenzene + 1-ethyl-3-methylimidazolium ethylsulfate) have been determined experimentally at T = 298.15 K and atmospheric pressure. The solubility curves and the tie-line compositions of the conjugate phases were obtained by means of density. The degree of consistency of the tie-lines was tested using the Othmer-Tobias equation, and the Non-Random Two-Liquid (NRTL) and the Universal Quasi-Chemical (UNIQUAC) models were used to correlate the phase equilibrium in the systems. Selectivity and solute distribution ratio were evaluated for the immiscible region.

  18. Distributions of hit-numbers in single targets

    Energy Technology Data Exchange (ETDEWEB)

    Fowler, J F [Postgraduate Medical School, Hammersmith Hospital, London (United Kingdom)

    1966-07-01

    Very general models can be proposed for relating the surviving proportion of an irradiated population of cells or bacteria to the absorbed dose, but if the number of free parameters is large the model can never be tested experimentally (Zimmer; Zirkie; Tobias). A relatively simple model is therefore proposed here, based on the physical facts of energy deposition in small volumes which are currently under active investigation (Rossi), and on cell-survival experiments over a wide range of LET (e.g. Barendsen et al.; Barendsen). It is not suggested that the model is correct or final, but only that its shortcomings should be demonstrated by comparison with experimental results before more complicated models are worth pursuing. It is basically a multihit model applied first to a single target volume, but also applicable to the situation where only one out of many potential target volumes has to be inactivated to kill the organism. It can be extended to two or more target volumes if necessary. Emphasis is placed upon the amount of energy locally deposited in certain sensitive volumes called 'target volumes'.

  19. Polyether ether ketone implants achieve increased bone fusion when coated with nano-sized hydroxyapatite: a histomorphometric study in rabbit bone

    Directory of Open Access Journals (Sweden)

    Johansson P

    2016-04-01

    Full Text Available Pär Johansson,1 Ryo Jimbo,1 Yoshihito Naito,2 Per Kjellin,3 Fredrik Currie,3 Ann Wennerberg1 1Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden; 2Oral Implant Center, Tokushima University Hospital, Tokushima, Japan; 3Promimic AB, Stena Center, Göteborg, Sweden Abstract: Polyether ether ketone (PEEK possesses excellent mechanical properties similar to those of human bone and is considered the best alternative material other than titanium for orthopedic spine and trauma implants. However, the deficient osteogenic properties and the bioinertness of PEEK limit its fields of application. The aim of this study was to limit these drawbacks by coating the surface of PEEK with nano-scaled hydroxyapatite (HA minerals. In the study, the biological response to PEEK, with and without HA coating, was investigated. Twenty-four screw-like and apically perforated implants in the rabbit femur were histologically evaluated at 3 weeks and 12 weeks after surgery. Twelve of the 24 implants were HA coated (test, and the remaining 12 served as uncoated PEEK controls. At 3 weeks and 12 weeks, the mean bone–implant contact was higher for test compared to control (P<0.05. The bone area inside the threads was comparable in the two groups, but the perforating hole showed more bone area for the HA-coated implants at both healing points (P<0.01. With these results, we conclude that nano-sized HA coating on PEEK implants significantly improved the osteogenic properties, and in a clinical situation this material composition may serve as an implant where a rapid bone fusion is essential. Keywords: HA, PEEK, osseointegration, histology, orthopedics, in vivo

  20. Liquid–liquid equilibria study of the (water + phosphoric acid + hexyl or cyclohexyl acetate) systems at T = (298.15, 308.15, and 318.15) K: Measurement and thermodynamic modelling

    International Nuclear Information System (INIS)

    Ghanadzadeh Gilani, A.; Ghanadzadeh Gilani, H.; Shekarsaraee, S.; Nasiri-Touli, E.; Seyed Saadat, S.L.

    2016-01-01

    Highlights: • Tie line data for aqueous solutions of phosphoric acid with esters were obtained. • The LLE data were correlated using the UNIQUAC and NRTL models. • The quality of the LLE data was validated using the appropriate equations. • Separation factors were calculated for the chosen solvents. - Abstract: Liquid–liquid equilibrium (LLE) data for the (water + phosphoric acid + n-hexyl acetate or cyclohexyl acetate) ternary systems were determined at T = (298.15, 308.15 and 318.15) K and p = 101.3 kPa. The cloud point method was used to obtain the solubility and the Karl-Fischer, acidimetric titration, and refractive index methods were used to determine the tie-line values. Both the ternary systems exhibit type-1 behavior of LLE. The experimental values were regressed and acceptably correlated using the UNIQUAC and NRTL models. The reliability of the experimental tie lines was confirmed using the Othmer–Tobias plot. Experimental distribution coefficients and separation factors were fitted using the Kamlet–Taft LSER model. The influence of temperature on the biphasic area and separation factor was found to be minor. As a result, both the esters are suitable separating agents for aqueous phosphoric acid mixtures.

  1. Tie line data for the (water + butyric acid + n-butyl alcohol or amyl alcohol) at T = (298.2, 308.2, and 318.2) K and (water + butyric acid + isoamyl alcohol) at T = 298.2 K

    International Nuclear Information System (INIS)

    Ghanadzadeh Gilani, A.; Ghanadzadeh Gilani, H.; Amouzadeh, F.

    2014-01-01

    Highlights: • Liquid equilibrium data of (water + BA + alcohols) systems were measured. • Experimental LLE data were correlated with NRTL and UNIQUAC models. • Distribution coefficients and separation factors were evaluated. -- Abstract: In this study, solubility and tie-line data of the (water + butyric acid + n-butyl alcohol or amyl alcohol) ternary systems were determined at T = (298.2, 308.2, and 318.2) K and p = 101.3 kPa for the first time. Due to the structural similarity, the tie-line data for (water + butyric acid + isoamyl alcohol) system were also measured and correlated at T = 298.2 K. The ternary systems investigated display type-1 behaviour of LLE. The cloud point method was used to measure the solubility data and the Karl-Fischer, acidimetric titration, and refractive index methods were used to determine the tie-line data. For each system, the experimental tie-line data were correlated using the UNIQUAC and NRTL models. The Othmer–Tobias and Hand correlations equations were used to establish the quality of the LLE data. Experimental distribution coefficients and separation factors were evaluated over the immiscibility regions

  2. Quanta 5; Quanten 5

    Energy Technology Data Exchange (ETDEWEB)

    Kleinknecht, Konrad (ed.) [Heisenberg Gesellschaft e.V., Muenchen (Germany)

    2017-07-01

    ''Quanta 5'' contains the two speeches on the member meeting of the Heisenberg society in october 2016. Reinhard Werner talked about the meaning of Heisenberg's uncertainty relation and its interpretation in the framework of quantum mechanics. Johannes Bluemer reported about the works on cosmic radiation, which were performed during the second world war in Berlin and after the war in the Max-Planck institute for physics in Goettingen, as well as about the results of the latest experiments on the cosmic radiation. Reprinted is furthermore Heisenberg's speech ''Wandlungen der Grundlagen der exakten Naturwissenschaft in juengster Zeit'', which he gave in the meeting of the natural researchers at 17.9.1934 in Hanover. It is the reaction of Heisenberg on the attacks by Johannes Stark and Philipp Lenard on Jewish scientists and on the developments of modern Physics, especially on Einstein's relativity theory and quantum mechanics. The closure of the volume forms an essay of Tobias Jung about the importance of Heisenberg's house in Urfeld above the Bavarian Walchensee.

  3. Environmental political targets of the EU: German-French contributions for the achievement of the EU goals. Proceedings; Umweltpolitische Ziele der EU: Deutsch-franzoesische Beitraege zur Zielerreichung. Concepts franco-allemands pour atteindre les objectifs environnementaux de l'UE. Tagungsband. Actes

    Energy Technology Data Exchange (ETDEWEB)

    Cail, Sylvain; Moest, Dominik; Fichtner, Wolf; Percebois, Jacques (eds.)

    2009-07-01

    The first German-French workshop on energy economy and sustainability on January 29 and 30, 2009 at Karlsruhe (Federal Republic of Germany) comprised the following lectures: (1) Systematic evaluation of the sustainability in energy projects (Volker Stelzer); (2) Comparative value of various mechanisms of promoting renewable energy sources (Jacques Percebois, Olivier Rousse); (3) Communities as actors in climate protection (Lioba Markl, Nurten Avci); (4) The chain of value of photovoltaic systems containing crystalline silicon (Christin Oeser); (5) The wind power industry as an example of the German-French cooperation for the achievement of environmental political targets of the EU (Katharina Braig, Markus Jenne); (6) A short history of the future of biomass and biofuels in relation to white biotechnologies (Gerard Goma, Carole Molina-Jouve); (7) Generation and feeding of methane from biomass (Frank Graf); (8) Energy evaluation of the thickening of the biomass by rapid pyrolysis (Guillain Mauviel et al.); (9) Future role of renewable energies in European electricity supply (Dominik Moest et al.); (10) A systematic evaluation of the potentials for reducing CO{sub 2} as an element of company management (Sarah Schwarz); (11) A system dynamics model of the German electricity market (Tobias Jaeger).

  4. Quanta 5

    International Nuclear Information System (INIS)

    Kleinknecht, Konrad

    2017-01-01

    ''Quanta 5'' contains the two speeches on the member meeting of the Heisenberg society in october 2016. Reinhard Werner talked about the meaning of Heisenberg's uncertainty relation and its interpretation in the framework of quantum mechanics. Johannes Bluemer reported about the works on cosmic radiation, which were performed during the second world war in Berlin and after the war in the Max-Planck institute for physics in Goettingen, as well as about the results of the latest experiments on the cosmic radiation. Reprinted is furthermore Heisenberg's speech ''Wandlungen der Grundlagen der exakten Naturwissenschaft in juengster Zeit'', which he gave in the meeting of the natural researchers at 17.9.1934 in Hanover. It is the reaction of Heisenberg on the attacks by Johannes Stark and Philipp Lenard on Jewish scientists and on the developments of modern Physics, especially on Einstein's relativity theory and quantum mechanics. The closure of the volume forms an essay of Tobias Jung about the importance of Heisenberg's house in Urfeld above the Bavarian Walchensee.

  5. The self invented personality? Reflections on authenticity and writing analytic papers.

    Science.gov (United States)

    Astor, James

    2005-09-01

    One of the great themes of American literature is the self-invented personality, whether it is Scott Fitzgerald's Gatsby or one of Philip Roth's alter egos, such as Nathaniel Zuckerman. This is just one of several approaches which novelists employ. They take a problem from life, perhaps their own, and then embark on solving the problem of the book-which is how to write about this. Sometimes, as in Tobias Wolff's novel Old School, the personality of the narrator is woven into an exploration of the creative process itself. Wolff's novel concerns itself not just with writing but with how to become a writer. I explore how this process is similar to both writing about analysis and becoming an analyst. In doing this I discuss issues of authenticity, fiction, art, the effects of identification, the power of the super-ego, supervision and learning, integrity of life and work, envy and the xenocidal impulse, the regulation of our profession and the loss of trust, and in so doing join in discussion with Plaut, Wharton, Tuckett and others about professional communications, the internal world and the mysteriousness of our relation to our internal objects.

  6. Ecoturismo de aventura: un turismo regional asociativo

    Directory of Open Access Journals (Sweden)

    Javier Gómez

    2003-11-01

    Full Text Available En Colombia se empezó a hablar de turismo de aventura hacia el año de 1994, cuando en San Gil (Santander se inicia la operación de productos turísticos que incluían actividades como rafting, rappel, escalada, caminatas y espeleología. Dados los buenos resultados, este tipo de turismo va encontrando nuevos escenarios en el río Negro, en Tobia, y en el río Bogotá, en Suesca, dos municipios ubicados en el departamento de Cundinamarca. Posteriormente, en el río Sumapaz (municipio de Melgar, Tolima, con el apoyo de algunas cajas de compensación. Estas experiencias han generado procesos de capacitación en varias regiones del país, cuyo fin es que los pobladores creen empresas mediante formas asociativas y encuentren en el ecoturismo y en el turismo de aventura nuevas posibilidades de desarrollo. Estas dos formas de turismo exigen de un trabajo concertado con las comunidades receptoras; debe existir un compromiso de los actores para asegurar la sostenibilidad de los destinos y consolidar beneficios reales para sus habitantes.

  7. Spinal anesthesia after intraoperative cardiac arrest during general anesthesia in an infant

    Directory of Open Access Journals (Sweden)

    Whitaker EE

    2017-03-01

    Full Text Available Emmett E Whitaker,1,2 Veronica Miler,1,2 Jason Bryant,1,2 Stephanie Proicou,1 Rama Jayanthi,3,4 Joseph D Tobias1,2 1Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, 2Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, 3Division of Pediatric Urology, Nationwide Children’s Hospital, 4Department of Urology, The Ohio State University College of Medicine, Columbus, OH, USA Abstract: Although generally safe and effective, severe perioperative complications, including cardiac arrest, may occur during general anesthesia in infants. With the emergence of evidence that specific anesthetic agents may affect future neurocognitive outcomes, there has been an increased focus on alternatives to general anesthesia, including spinal anesthesia. We present a case of cardiac arrest during general anesthesia in an infant who required urologic surgery. During the subsequent anesthetic care, spinal anesthesia was offered as an alternative to general anesthesia. The risks of severe perioperative complications during general anesthesia are reviewed, etiologic factors for such events are presented, and the use of spinal anesthesia as an alternative to general anesthesia is discussed. Keywords: child, pediatric anesthesia, complications

  8. Book Reviews

    Directory of Open Access Journals (Sweden)

    S. Husin Ali

    1977-04-01

    Full Text Available - G.A. Nagelkerke, Gerard J. Telkamp, Bouwstoffen voor de sociaal-economische geschiedenis van Indonesië van ca. 1900 tot 1940; een beschrijvende bibliografie; Koloniale studiën, 1916-1941; Koloniaal tijdschrift, 1912-1941. Amsterdam, Koninklijk Instituut voor de Tropen, 1977. 89 pp. - H.J. de Graaf, W.Ph. Coolhaas, Generale Missiven van Gouverneur-Generaal en Raden aan Heren XVII der Verenigde Oostindische Compagnie. Deel VI: 1698-1713. Uitgegeven door Dr. W.Ph. Coolhaas. Martinus Nijhoff, ‘s-Gravenhage 1976. XVI & 1000 blzn. Rijks Geschiedkundige Publicatiën. Grote Serie no. 159. - C.D. Grijns, John H. Wolff, Beginning Indonesian. Two parts, Southeast Asia Program, Cornell University, Ithaca, New York, 1971, 534 + 556 pp. tapes. - A. Ploeg, Fredrik Barth, Ritual and knowledge among the Baktaman of New Guinea. Universitetsforlaget, Oslo / Yale University Press, New Haven, 1975, 292 pp., maps, plates, figures, appendices, index. - A. Teeuw, Harry Aveling, Contemporary Indonesian poetry. Poems in Bahasa Indonesia and English by W.S. Rendra, Ajip Rosidi, Subagio Sastrowardojo, Toeti Heraty, Taufiq Ismail, Goenawan Mohamad, Sapardi Djoko Damono. Edited and translated by Harry Aveling. University of Queensland Press, Asian and Pacific Writing 5, St Lucia, Queensland 1975. 261 pp. - C. van Dijk, C. Smit, De dekolonisatie van Indonesië. H.D. Tjeenk (edition, Oxford University Press, 176 pp. - H.J.M. Claessen, S. Husin Ali, Malay peasant society and leadership. Kuala Lumpur: Oxford University Press, 1975. 192 pp. Bibliography, register, maps, tables, figures. - J.J. Romkes, Rodney Needham, Belief, language and experience. Basil Blackwell, Oxford 1972. XVII, 269 p. - J.B. Avé, Erik Jensen, The Iban and their Religion. Oxford Monographs on social anthropology. Oxford at the Clarendon Press, 1974, VIII, 242 pp.

  9. PREFACE: 12th European Workshop on Advanced Control and Diagnosis (ACD 2015)

    Science.gov (United States)

    Straka, Ondřej; Punčochář, Ivo; Duník, Jindřich

    2015-11-01

    The 12th European Workshop on Advanced Control and Diagnosis (ACD 2015) took place at the Research Centre NTIS - New Technologies for the Information Society, Faculty of Applied Sciences, University of West Bohemia, Pilsen, Czech Republic, on November 19 - 20, 2015. The annual European Workshop on Advanced Control and Diagnosis has been organized since 2003 by Control Engineering departments of several European universities in Germany, France, the UK, Poland, Italy, Hungary, and Denmark to bring together senior and junior academics and engineers from diverse fields of automatic control, fault detection, and signal processing. The workshop provides an opportunity for researchers and developers to present their recent theoretical developments, practical applications, or even open problems. It also offers a great opportunity for industrial partners to express their needs and priorities and to review the current activities in the fields. A total of 74 papers have been submitted for ACD 2015. Based on the peer reviews 48 papers were accepted for the oral presentation and 10 papers for the poster presentation. The accepted papers covered areas of control theory and applications, identification, estimation, signal processing, and fault detection. In addition, four excellent plenary lectures were delivered by Prof. Fredrik Gustafsson (Automotive Sensor Mining for Tire Pressure Monitoring), Prof. Vladimír Havlena (Advanced Process Control for Energy Efficiency), Prof. Silvio Simani (Advanced Issues on Wind Turbine Modelling and Control), and Prof. Robert Babuška (Learning Control in Robotics). The ACD 2015 was for the first time in the workshop history co-sponsored by the International Federation of Automatic Control (IFAC). On behalf of the ACD 2015 organising committee, we would like to thank all those who prepared and submitted papers, participated in the peer review process, supported, and attended the workshop.

  10. Energy efficiency. A constant challenge to science and practice. Proceedings. 2. ed.; Energieeffizienz. Eine stete Herausforderung an Wissenschaft und Praxis. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Ulrich (ed.)

    2011-07-01

    Within the meeting ''Energy efficiency'' of the Research Center for Energy Economics (Munich, Federal Republic of Germany) from 12th to 13th May, 2011, at the Munich Residenz (Munich, Federal Republic of Germany) the following lectures were presented: (1) Innovation and research for an enhanced energy efficiency - New accents in the energy research politics of the Federal Government (Knut Kuebler); (2) Revolution of efficiency in the monastery St. Ottilien (Wolfgang Mauch); (3) From the maser plan to the local plan of energy utilization (Tobias Schmid); (4) The life cycle approach as a driver for innovative energy contracting (Alfred Gayer); (5) Energy efficiency networks (Anna Gruber); (6) Grid expansion for an enhanced utilization of renewable energies (Martin Fuchs); (7) Storage requirement in the electrical grid; (8) Scenarios for the development of the electromobility in Munich (Stephan Brunnert); (9) Li ion batteries for electrified automobiles - Demands and status (Peter Lamp); (10) Marketing of wind power (Serafin von Roon); (11) Demand side management in non-residential buildings (Johannes Jungwirth); (12) Energy future 2050 (Ulrich Wagner); (13) Decentral and renewable power generation (Ulli Arndt); (14) Electromobility - is that the future? (Markus Lienkamp); (14) Electric power - Reason or solution of the climate problem? (Harald Lesch).

  11. Alkylsulfate-based ionic liquids in the liquid–liquid extraction of aromatic hydrocarbons

    International Nuclear Information System (INIS)

    García, Silvia; Larriba, Marcos; García, Julián; Torrecilla, José S.; Rodríguez, Francisco

    2012-01-01

    Highlights: ► Values of α 2,1 for the four R-SO 4 ionic liquids are higher than those of sulfolane. ► Values of D 2 for all the ionic liquids are lower than those of sulfolane. ► Values of D 2 for [emim][C 2 H 5 SO 4 ] are the highest among the R-SO 4 ionic liquids. - Abstract: The (liquid + liquid) equilibrium data (LLE) for the extraction of toluene from heptane with different ionic liquids (ILs) based on the alkylsulfate anion (R-SO 4 ) was determined at T = 313.2 K and atmospheric pressure. The effect of more complex R-SO 4 anions on capacity of extraction and selectivity in the liquid–liquid extraction of toluene from heptane was studied. The ternary systems were formed by {heptane + toluene + 1,3-dimethylimidazolium methylsulfate ([mmim][CH 3 SO 4 ]), 1-ethyl-3-methylimidazolium hydrogensulfate ([emim][HSO 4 ]), 1-ethyl-3-methylimidazolium methylsulfate ([emim][CH 3 SO 4 ]), or 1-ethyl-3-methylimidazolium ethylsulfate ([emim][C 2 H 5 SO 4 ])}. The degree of quality of the experimental LLE data was ascertained by applying the Othmer–Tobias correlation. The phase diagrams for the ternary systems were plotted, and the tie lines correlated with the NRTL model compare satisfactorily with the experimental data.

  12. Energy efficiency. A constant challenge to science and practice. Proceedings. 2. ed.; Energieeffizienz. Eine stete Herausforderung an Wissenschaft und Praxis. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Ulrich [ed.

    2011-07-01

    Within the meeting ''Energy efficiency'' of the Research Center for Energy Economics (Munich, Federal Republic of Germany) from 12th to 13th May, 2011, at the Munich Residenz (Munich, Federal Republic of Germany) the following lectures were presented: (1) Innovation and research for an enhanced energy efficiency - New accents in the energy research politics of the Federal Government (Knut Kuebler); (2) Revolution of efficiency in the monastery St. Ottilien (Wolfgang Mauch); (3) From the maser plan to the local plan of energy utilization (Tobias Schmid); (4) The life cycle approach as a driver for innovative energy contracting (Alfred Gayer); (5) Energy efficiency networks (Anna Gruber); (6) Grid expansion for an enhanced utilization of renewable energies (Martin Fuchs); (7) Storage requirement in the electrical grid; (8) Scenarios for the development of the electromobility in Munich (Stephan Brunnert); (9) Li ion batteries for electrified automobiles - Demands and status (Peter Lamp); (10) Marketing of wind power (Serafin von Roon); (11) Demand side management in non-residential buildings (Johannes Jungwirth); (12) Energy future 2050 (Ulrich Wagner); (13) Decentral and renewable power generation (Ulli Arndt); (14) Electromobility - is that the future? (Markus Lienkamp); (14) Electric power - Reason or solution of the climate problem? (Harald Lesch).

  13. Final report on the Swedish participation in Annex 37 of the International Energy Agency (IEA), 2010 - 2012; Slutrapport oever svensk medverkan i Internationella energiraadets (IEA) Annex 37, 2010 - 2012

    Energy Technology Data Exchange (ETDEWEB)

    Persson, Tobias

    2012-07-01

    The National Team Leader within the International Energy Agency (IEA) task 37 during 2010 - 2012 has been Anneli Petersson and Tobias Persson from Swedish Gas Technology Center (SGC). In total 14 countries and the EU have been members within the task. The following countries have been members in Task 37 during 2010 - 2012: Brazil, Denmark, Ireland, Canada, France, Finland, The Netherlands, Norway, Turkey, Germany, Switzerland, United Kingdom, Sweden, Austria. The meetings within the task have been situated in the new member countries to get insight into the biogas situation and biogas development in these countries. The work within the group has been focused on eight areas: Substrates for biogas production, Optimisation of digestion processes, Biogas upgrading and pipeline injection, Digestate processing and quality, Emissions from biogas installations, Information and education, Workshops and seminars, Joint projects with other IEA Bioenergy tasks. All presentations from the meetings and workshops and other published material can be downloaded from the home page of task 37 www.iea-biogas.net. During the period 2010 - 2012 has the following brochures been published: 1. Biogas from crop digestion. 2. Utilisation of digestate from biogas plants as bio fertiliser. 3. Quality management of digestate from biogas plants used as fertiliser.

  14. Separation of benzene from alkanes using 1-ethyl-3-methylpyridinium ethylsulfate ionic liquid at several temperatures and atmospheric pressure: Effect of the size of the aliphatic hydrocarbons

    International Nuclear Information System (INIS)

    Gonzalez, Emilio J.; Calvar, Noelia; Gomez, Elena; Dominguez, Angeles

    2010-01-01

    The ionic liquid 1-ethyl-3-methylpyridinium ethylsulfate, [EMpy][ESO 4 ], was studied for the separation of benzene from aliphatic hydrocarbons (octane or nonane) by solvent extraction through the determination of the (liquid + liquid) equilibrium (LLE) of the ternary systems: {octane (1) + benzene (2) + [EMpy][ESO 4 ] (3)} and {nonane (1) + benzene (2) + [EMpy][ESO 4 ] (3)} at T = (283.15 and 298.15) K and atmospheric pressure. Binodal curves were determined using the 'cloud point' method, and tie-line compositions were obtained by density measurements. The values of selectivity and distribution coefficient, derived from the tie-line data, were used to decide if this ionic liquid can be used as potential solvent for the separation of benzene from aliphatic hydrocarbons using liquid extraction. These results were analyzed and compared to those previously reported for the systems {hexane + benzene + [EMpy][ESO 4 ]} and {heptane + benzene + [EMpy][ESO 4 ]}. The experimental results show that this ionic liquid is suitable for the extraction of benzene from mixtures containing octane and nonane. The consistency of tie-line data was ascertained by applying the Othmer-Tobias and Hand equations. The experimental results for the ternary systems were well correlated with the NRTL model. No literature data were found for the mixtures discussed in this paper.

  15. Edinburgh, the Scottish pioneers of anatomy and their lasting influence in South Africa.

    Science.gov (United States)

    Correia, J C; Wessels, Q; Vorster, W

    2013-11-01

    The history of the origin of anatomy education in South Africa is the history of an arduous journey through time. The lasting influence of Edinburgh came in the form of Robert Black Thomson. He was a student and assistant of Sir William Turner who gave rise to the first chair of anatomy and the establishment of a department at the South African College, known today as University of Cape Town. Thomson was later succeeded by Matthew Drennan, a keen anthropologist, who was revered by his students. This Scottish link prevailed over time with the appointment of Edward Philip Stibbe as the chair of anatomy at the South African School of Mines and Technology, which later became the University of the Witwatersrand. Stibbe's successor, Raymond Arthur Dart, a graduate of the University of Sydney, was trained in an anatomy department sculpted on that of Edinburgh by Professor James Thomas Wilson. Wilson's influence at the University of Sydney can be traced back to Edinburgh and William Turner through Thomas Anderson Stuart. Both Dart and Robert Broom, another Scot, were considered as Africa's wild men by the late Professor Tobias. Here, the authors explore the Scottish link and origins of anatomy pedagogy in South Africa.

  16. Intelligent and efficient use of renewable energy sources in Saxonia and Czech Republic. Technical, economic and legal aspects; Intelligenter und effizienter Einsatz von (er)neu(erbar)en Energien in Sachsen und Tschechien. Technische, wirtschaftliche und rechtliche Aspekte

    Energy Technology Data Exchange (ETDEWEB)

    Gramlich, Ludwig; Orantek, Kerstin (eds.)

    2011-07-01

    Within the meeting in Oberwiesenthal (Federal Republic of Germany) between 30th September and 02nd October, 2011, the following lectures were held: (a) Utilization of renewable energy sources in Czech Republic (Martin Neruda); (b) Scenarios of energy and ecology development in the next 20 years (Behumir Stedron); (c) Climatic protection and emission trading (Rainer Wolf); (d) Nuclear energy - suicide mission or glimmer of hope (Michael Hietschold); (e) Energetic questions in areas near to the area (Martin Maslaton); (f) Climatic protection and renewable energy sources in the Vogtland district - State of the art and problems (Tobias Pohl); (g) Complex reconstruction of plate buildings - economic and energetic potential (Jan Antonin); (h) Ecologic forms of traffic and their preferential treatment in metropolises (Jana Halirova); (i) Utilization of renewable energy sources in air traffic (Rosina Kasica); (j) Smart Metering - on the way to an economical technology? (Uwe Goetze); (k) Integration of an enhanced number of electric vehicles in the low voltage network (Jens Teuscher); (l) Intelligent electric cars and the concept of green energy (Zdenek Votruba); (m) Smart grids under the conditions of Czech Republic (Petr Marecek); (n) Possibilities of utilization of nuclear power plants as a source for a central heat supply of neighbouring agglomerations - with focus on Czech Republic (Tomas Kralik).

  17. Stakeholder analysis of perceived relevance of connectivity - the implication to your research

    Science.gov (United States)

    Smetanova, Anna; Müller, Eva Nora Nora; Fernández-Getino, Ana Patricia; José Marqués, María; Vericat, Damià; Dugodan, Recep; Kapovic, Marijana; Ljusa, Melisa; Ferreira, Carla Sofia; Cavalli, Marco; Marttila, Hannu; Broja, Manuel Esteban Lucas; Święchowicz, Jolanta; Zumr, David

    2016-04-01

    conducting interview with a stakeholder: Charles Bielders (Catholic University Louvain, Belgium), Frédéric Darboux (Department of Soil Science Orléans, INRA, France), Dragana Dordevic (Centre of Chemistry, University of Belgrade, Serbia), Tobias Heckmann (Catholic University of Eichstätt-Ingolstadt, Germany), Anna Kidová (Institute of Geography, Slovak Academy of Sciences, Slovakia), Tobias Krüger (Integrative Research Institute on Transformations of Human-Environment Systems, Humboldt University, Germany), Carly Maynard (Department of Geography and the Lived Environment, University of Edinburgh, UK), Eva Mockler, (School of Civil, Structural and Environmental Engineering , University College Dublin, Ireland), Tony Parsons, (Department of Geography, University Sheffield, UK), Thorunn Petursdottir (RECARE, Soil Conservation Service of Iceland, Iceland), Ronald Pöppel (Institute of Geography and Regional Research, University Vienna, Austria), Jerzy Rejman (Institute of Agronomy, Polish Academy of Sciences, Poland), Jose López-Tarazón (Institute of Earth and Environmental Sciences, University of Potsdam, Germany), Sophie Tindale (Department of Geography, University, Durham, UK), Brigitta Tóth (Department of Crop Production and Soil Sciences, Pannonian University, Hungary) and Marco Vainu (Institute of Ecology, Tallinn University, Estonia). The project was supported by COST-STSM-ECOST-STSM-ES1306-011215-063624.

  18. Separation of toluene from cyclic hydrocarbons using 1-butyl-3-methylimidazolium methylsulfate ionic liquid at T = 298.15 K and atmospheric pressure

    International Nuclear Information System (INIS)

    Dominguez, Irene; Calvar, Noelia; Gomez, Elena; Dominguez, Angeles

    2011-01-01

    Highlights: → [BMim][MSO 4 ] was studied as solvent to extract toluene from cyclic hydrocarbons. → (Liquid + liquid) equilibrium data were measured at 298.15K and atmospheric pressure. → Selectivity and solute distribution ratio were obtained and compared with literature. → Experimental data were satisfactorily correlated using NRTL and UNIQUAC models. → [BMim][MSO 4 ] can be used as solvent for the studied (liquid + liquid) extraction. - Abstract: In this paper the extraction of toluene from cyclic hydrocarbons (cyclohexane, or methylcyclohexane, or cyclooctane, or cyclohexene) was analyzed by liquid extraction with 1-butyl-3-methylimidazolium methylsulfate ionic liquid, [BMim][MSO 4 ], as solvent. The experimental (liquid + liquid) equilibrium (LLE) data were determined at T = 298.15 K and atmospheric pressure. Solubility curves were obtained by the cloud point method and tie-line compositions were determined by density measurement. An analysis of the influence of different cyclic hydrocarbons on the extraction was performed. The effectiveness of the extraction of toluene from cyclic hydrocarbons was evaluated by means of the solute distribution ratio and selectivity values. The degree of consistency of the experimental LLE data was ascertained using the Othmer-Tobias and Hand equations. The experimental data for the (liquid + liquid) equilibria of the ternary systems were correlated with the Non-Random Two-Liquid (NRTL) and UNIversal QUAsi-Chemical (UNIQUAC) thermodynamic models.

  19. (Liquid + liquid) equilibria of four alcohol–water systems containing 1,8-cineole at T = 298.15 K

    International Nuclear Information System (INIS)

    Li, Hengde; Feng, Zhangni; Wan, Li; Huang, Cheng; Zhang, Tianfei; Fang, Yanxiong

    2016-01-01

    Graphical abstract: (Liquid + liquid) equilibria of C_1–C_4 alcohol–water systems containing 1,8-cineole are presented. Distribution ratios of alcohol in the mixtures are examined. The immiscible region of the LLE systems is evaluated and discussed. - Highlights: • Ternary (liquid + liquid) equilibria containing 1,8-cineole are presented. • Distribution ratios of C_1–C_4 alcohol in the mixtures are examined. • The LLE values were correlated using the NRTL and UNIQUAC models. - Abstract: As an eco-friendly compound from essential oils, 1,8-cineole (cineole, eucalyptol) has the potential to replace the ozone depleting industrial solvents. This paper presents experimental (liquid + liquid) equilibrium (LLE) data for four alcohol–water systems containing 1,8-cineole. To evaluate the phase equilibrium properties of 1,8-cineole in aqueous alcohol mixtures, LLE values for the ternary systems (water + methanol or ethanol or 1-propanol or 1-butanol + 1,8-cineole) were determined with a tie-line method at T = 298.15 K under atmospheric pressure. The well-known Hand, Bachman and Othmer–Tobias equations were used to test the reliability of the experimental results. The binodal curves and distribution ratios of alcohol in the mixtures are shown and discussed. The experimental LLE values were satisfactorily correlated by the NRTL and UNIQUAC models.

  20. Síndrome de sobrecarga y grado de funcionalidad familiar en cuidadores de personas con cáncer del hospital de niños Rafael Tobías Guevara de Barcelona, estado Anzoátegui, Venezuela | Caregiver burden syndrome and degree of family functionality in caregivers of people with cancer of children´s hospital Rafael Tobías Guevara in Barcelona, Anzoátegui state, Venezuela

    Directory of Open Access Journals (Sweden)

    Ramón Marcano Caraballo

    2017-11-01

    Full Text Available When a family member assumes the role of caregiver, it is the family cohesion one of the key elements in the development of caregiver burden syndrome, being in turn the adaptive response of the family a factor that positively affects the course of the disease. Therefore, the objective of the study was to determine the presence of caregiver burden syndrome and its relation to the level of family functionality present in caregivers of patients with cancer at the oncology unit of Children's Hospital Rafael Tobias Guevara located in Barcelona, Anzoátegui state. The study was performed between February and April 2015, through a transversal and descriptive research. The data were collected through the Zarit Caregiver Burden Interview and family APGAR questionnaire. From the 23 cases evaluated, the female gender predominated among caregivers of cancer patients, the age group 18-30 years and caring times between 13-24 months. Regarding the level of caregiver burden syndrome in caregivers, 14 cases (60.86% showed it, represented by seven cases (30.43% with mild caregiver burden and seven cases (30.43% with intense caregiver burden. It was concluded that a greater degree of family functioning promoted a lower prevalence of caregiver burden syndrome. In addition, a direct relationship was shown between the time spent on patient care and the level of caregiver burden syndrome present in the caregiver.

  1. Light-ion therapy in the US: From the Bevalac to ??

    International Nuclear Information System (INIS)

    Alonso, Jose R.; Castro, Joseph R.

    2002-01-01

    While working with E.O. Lawrence at Berkeley, R.R. Wilson in 1946 noted the potential for using the Bragg-peak of protons (or heavier ions) for radiation therapy. Thus began the long history of contributions from Berkeley to this field. Pioneering work by C.A. Tobias et al at the 184-Inch Synchrocyclotron led ultimately to clinical applications of proton and helium beams, with over 1000 patients treated through 1974 with high-energy plateau radiation; placing the treatment volume (mostly pituitary fields) at the rotational center of a sophisticated patient positioner. In 1974 the SuperHILAC and Bevatron accelerators at the Lawrence Berkeley Laboratory were joined by the construction of a 250-meter transfer line, forming the Bevalac, a facility capable of accelerating ions of any atomic species to relativistic energies. With the advent of these new beams, and better diagnostic tools capable of more precise definition of tumor volume and determination of the stopping point of charged-particle beams, large-field Bragg-peak therapy with ion beams became a real possibility. A dedicated Biomedical experimental area was developed, ultimately consisting of three distinct irradiation stations; two dedicated to therapy and one to radiobiology and biophysics. These facilities included dedicated support areas for patient setup and staging of animal and cell samples, and a central control area linked to the main Bevatron control room

  2. Workshop presentations

    International Nuclear Information System (INIS)

    Sanden, Per-Olof; Edland, Anne; Reiersen, Craig; Mullins, Peter; Ingemarsson, Karl-Fredrik; Bouchard, Andre; Watts, Germaine; Johnstone, John; Hollnagel, Erik; Ramberg, Patric; Reiman, Teemu

    2009-01-01

    An important part of the workshop was a series of invited presentations. The presentations were intended to both provide the participants with an understanding of various organisational approaches and activities as well as to stimulate the exchange of ideas during the small group discussion sessions. The presentation subjects ranged from current organisational regulations and licensee activities to new organisational research and the benefits of viewing organisations from a different perspective. There were more than a dozen invited presentations. The initial set of presentations gave the participants an overview of the background, structure, and aims of the workshop. This included a short presentation on the results from the regulatory responses to the pre-workshop survey. Representatives from four countries (Sweden, Canada, Finland, and the United Kingdom) expanded upon their survey responses with detailed presentations on both regulatory and licensee safety-related organisational activities in their countries. There were also presentations on new research concerning how to evaluate safety critical organisations and on a resilience engineering perspective to safety critical organisations. Below is the list of the presentations, the slides of which being available in Appendix 2: 1 - Workshop Welcome (Per-Olof Sanden); 2 - CSNI Working Group on Human and Organisational Factors (Craig Reiersen); 3 - Regulatory expectations on justification of suitability of licensee organisational structures, resources and competencies (Anne Edland); 4 - Justifying the suitability of licensee organisational structures, resources and competencies (Karl-Fredrik Ingemarsson); 5 - Nuclear Organisational Suitability in Canada (Andre Bouchard); 6 - Designing and Resourcing for Safety and Effectiveness (Germaine Watts); 7 - Organisational Suitability - What do you need and how do you know that you've got it? (Craig Reiersen); 8 - Suitability of Organisations - UK Regulator's View (Peter

  3. Perceived stress at transition to workplace: a qualitative interview study exploring final-year medical students’ needs

    Directory of Open Access Journals (Sweden)

    Moczko TR

    2016-01-01

    Full Text Available Tobias R Moczko,1,2,* Till J Bugaj,1,* Wolfgang Herzog,1 Christoph Nikendei1 1Department for General Internal and Psychosomatic Medicine, University Hospital of Heidelberg, Heidelberg, 2School of Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany *These authors contributed equally to this work Objectives: This study was designed to explore final-year medical students’ stressors and coping strategies at the transition to the clinical workplace. Methods: In this qualitative study, semi-standardized interviews with eight final-year medical students (five male, three female; aged 25.9±1.4 years were conducted during their internal medicine rotation. After verbatim transcription, a qualitative content analysis of students’ impressions of stress provoking and easing factors during final-year education was performed. Results: Students’ statements regarding burdens and dealing with stress were classified into four main categories: A perceived stressors and provoking factors, B stress-induced consequences, C personal and external resources for preventing and dealing with stress, and D final-year students’ suggestions for workplace improvement. Conclusion: Final-year medical students perceived different types of stress during their transition to medical wards, and reported both negative consequences and coping resources concerning perceived stress. As supervision, feedback, and coping strategies played an important role in the students’ perception of stress, final-year medical education curricula development should focus on these specifically. Keywords: undergraduate medical education, stress prevention, final-year medical education, workplace learning, qualitative research

  4. Application of [HMim][NTf2], [HMim][TfO] and [BMim][TfO] ionic liquids on the extraction of toluene from alkanes: Effect of the anion and the alkyl chain length of the cation on the LLE

    International Nuclear Information System (INIS)

    Corderí, Sandra; González, Emilio J.; Calvar, Noelia; Domínguez, Ángeles

    2012-01-01

    Highlights: ► Several ionic liquids were studied as solvent to extract toluene from heptane and cyclohexane. ► (Liquid + liquid) equilibrium data were measured at 298.15 K and atmospheric pressure. ► Selectivity and solute distribution ratio were calculated and compared with those found in literature for sulfolane. ► Experimental data were correlated using NRTL and UNIQUAC thermodynamic models. - Abstract: In this paper, the separation of toluene from the aliphatic hydrocarbons heptane and cyclohexane employing the ionic liquids 1-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, [HMim][NTf 2 ], 1-hexyl-3-methylimidazolium trifluoromethanesulfonate, [HMim][TfO] and 1-butyl-3-methylimidazolium trifluoromethanesulfonate, [BMim][TfO], as solvents was studied and discussed. Liquid–liquid equilibrium data for the ternary systems {heptane, or cyclohexane + toluene + [HMim][NTf 2 ], or [HMim][TfO], or [BMim][TfO]} and {heptane + cyclohexane + [HMim][NTf 2 ], or [HMim][TfO], or [BMim][TfO]} were measured at T = 298.15 K and atmospheric pressure. The degree of consistency of the tie-lines was tested using the Othmer–Tobias equation. The solute distribution ratio and selectivity, derived from the experimental tie-lines, were used to determine if these ionic liquids can be used as potential solvents on the extraction of toluene from aliphatic hydrocarbons; a comparison with literature data where sulfolane is used as solvent was also included. Finally, the experimental data were correlated with the NRTL and UNIQUAC thermodynamic models.

  5. Liquid–liquid extraction of toluene from alkane with pyridinium based ionic liquid ([BPy][NO3] and [HPy][NO3]) at 298.15 K and atmospheric pressure

    International Nuclear Information System (INIS)

    Enayati, Mobin; Mokhtarani, Babak; Sharifi, Ali; Anvari, Sanam; Mirzaei, Mojtaba

    2016-01-01

    Highlights: • Extraction of toluene from alkane with pyridinium based ionic liquid was studied. • The ionic liquids [BPy][NO 3 ] and [HPy][NO 3 ] were used. • The effect of alkane chain length on selectivity of toluene was evaluated. • The effect of alkyl chain length of ionic liquids on toluene selectivity was investigated. • The experimental data were correlated with the NRTL model. - Abstract: The focus of this paper is to study the liquid−liquid extraction process for the separation of toluene from alkane employing the ionic liquids N-butylpyridinium nitrate, [BPy][NO 3 ], and N-hexylpyridinium nitrate, [HPy][NO 3 ], as a new solvents. New experimental data for the ternary systems of {[BPy][NO 3 ] (1) + heptane, or octane, or decane (2) + toluene (3)} and {[HPy][NO 3 ] (1) + heptane, or octane, or decane (2) + toluene (3)} at T = 298.15 K and atmospheric pressure are reported. The Othmer-Tobias and Hand correlation are examined to check the reliability of the experimental LLE data. The toluene distribution ratios and selectivity were calculated form the experimental data. The selectivity values are higher than unity which indicates the ILs, [BPy][NO 3 ] and [HPy][NO 3 ], used in this work are potential solvents to separate toluene from alkane. Besides, the effect of the alkane chain length in the selectivity values was evaluated. In addition, the result of the NRTL thermodynamic modeling shows, the experimental data were satisfactorily correlated.

  6. Spinal anesthesia instead of general anesthesia for infants undergoing tendon Achilles lengthening

    Directory of Open Access Journals (Sweden)

    AlSuhebani M

    2018-05-01

    Full Text Available Mohammad AlSuhebani,1 David P Martin,1,2 Lance M Relland,1,2 Tarun Bhalla,1,2 Allan C Beebe,3 Amanda T Whitaker,3 Walter Samora,3 Joseph D Tobias1,2 1Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 2Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USA; 3Department of Orthopedic Surgery, Nationwide Children’s Hospital and The Ohio State University College of Medicine, Columbus, OH, USA Abstract: Spinal anesthesia (SA has been used relatively sparingly in the pediatric population, as it is typically reserved for patients in whom the perceived risk of general anesthesia is high due to comorbid conditions. Recently, concern has been expressed regarding the potential long-term neurocognitive effects of general anesthesia during the early stages of life. In view of this, our center has developed a program in which SA may be used as the sole agent for applicable surgical procedures. While this approach in children is commonly used for urologic or abdominal surgical procedures, there have been a limited number of reports of its use for orthopedic procedures in this population. We present the use of SA for 6 infants undergoing tendon Achilles lengthening, review the use of SA in orthopedic surgery, describe our protocols and dosing regimens, and discuss the potential adverse effects related to this technique. Keywords: spinal anesthesia, orthopedic surgery, tendon Achilles lengthening

  7. Influence of the temperature on the (liquid + liquid) phase equilibria of (water + 1-propanl + linalool or geraniol)

    International Nuclear Information System (INIS)

    Wan, Li; Li, Hengde; Huang, Cheng; Feng, Yuqing; Chu, Guoqiang; Zheng, Yuying; Tan, Wei; Qin, Yanlin; Sun, Dalei; Fang, Yanxiong

    2017-01-01

    Highlights: • Ternary LLEs containing linalool and geraniol are presented. • Distribution ratios of 1-propanol in the mixtures are examined. • Influence of the temperature on the LLE is studied. • The LLE data were correlated using the NRTL and UNIQUAC models. - Abstract: Linalool and geraniol are the primary components of rose oil, palmarosa oil, and citronella oil and many other essential oils, and two important compounds used in the flavour and fragrance, cosmetic or pharmaceutical industries. Phase equilibria (LLE, VLE, solubility, etc.) and related thermodynamic properties of a mixture are essential in the processes design and control of mass transfer process. In this work, experimental (liquid + liquid) equilibria data of the systems (water + 1-propanl + linalool) and (water + 1-propanl + geraniol) are presented. The (liquid + liquid) equilibria of both systems were determined with a tie-line method at T = (283.15, 298.15 and 313.15) K under atmospheric pressure. The well-known Hand, Bachman and Othmer–Tobias equations were used to test the reliability of the experimental values. The influence of the temperature on the (liquid + liquid) phase equilibria of the mixtures, the binodal curves and distribution ratios of 1-propanl are shown and discussed. Moreover, the NRTL and UNIQUAC models were applied to fit the data for both ternary systems. The interaction parameters obtained from both models successfully correlated the equilibrium compositions. Furthermore, the ternary systems could be represented using the binary parameters of the thermodynamic model with a function of temperature.

  8. Using Feedback to Promote Physical Activity: The Role of the Feedback Sign.

    Science.gov (United States)

    Kramer, Jan-Niklas; Kowatsch, Tobias

    2017-06-02

    Providing feedback is a technique to promote health behavior that is emphasized by behavior change theories. However, these theories make contradicting predictions regarding the effect of the feedback sign-that is, whether the feedback signals success or failure. Thus, it is unclear whether positive or negative feedback leads to more favorable behavior change in a health behavior intervention. The aim of this study was to examine the effect of the feedback sign in a health behavior change intervention. Data from participants (N=1623) of a 6-month physical activity intervention was used. Participants received a feedback email at the beginning of each month. Feedback was either positive or negative depending on the participants' physical activity in the previous month. In an exploratory analysis, change in monthly step count averages was used to evaluate the feedback effect. The feedback sign did not predict the change in monthly step count averages over the course of the intervention (b=-84.28, P=.28). Descriptive differences between positive and negative feedback can be explained by regression to the mean. The feedback sign might not influence the effect of monthly feedback emails sent out to participants of a large-scale physical activity intervention. However, randomized studies are needed to further support this conclusion. Limitations as well as opportunities for future research are discussed. ©Jan-Niklas Kramer, Tobias Kowatsch. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 02.06.2017.

  9. TU-G-210-03: Acoustic Simulations in Transcranial MRgFUS: Treatment Prediction and Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Vyas, U. [Stanford University (United States)

    2015-06-15

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO - An Integrative Approach to Model-Based Treatment Planning of Liver FUS Urvi Vyas – Acoustic Simulations in Transcranial MRgFUS: Treatment Prediction and Analysis Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  10. The sedimentological changes caused by human impact at the artificial channel of Medjerda-River (Coastal zone of Medjerda, Tunisia)

    Science.gov (United States)

    Benmoussa, Thouraya; Amrouni, Oula; Dezileau, Laurent; Mahé, Gil; Abdeljaouad, Saâdi

    2018-04-01

    Recent sedimentary and morphological changes at the new mouth of Medjerda-River (Gulf of Tunis) are investigated using a multiproxy approach of sediment cores complited by 210Pbex and 137Cs method dating. The subject of the study is to focus on surveying the sedimentary evolution of Medjerda-Raoued Delta caused by the human intervention in the management of the main tributaries of the Medjerda-River (artificial channel of Henchir Tobias). Sediment cores (CEM-1 and CEM-3) were subjected to both multiproxy approaches (Grain size, geochemical analysis and dating radiometric 210Pbex and 137Cs). The sedimentological analysis of the new deltaic deposits shows a progradation sequence with the silt and clay deposits on the historic sandy substratum. The mean grain size evolution on the old beach profile shows a decreasing trend from backshore (CEM-3) to nearshore (CEM-1). The geochemical results show varying concentrations of chemical elements such as Fe, K, Rb, Nb, Cr, Ti, Ba, Ca, Sr, Zr, V, and potentially toxic metal trace elements such as Pb, Zn and the As. The Principal component Analysis (PCA) applied in the geochemical elements evolution confirms the marine origin of the sand deposits in the basic layers of the two cores. The chronological method (210Pbex and 137Cs) affirms that the first fluvial deposits were set up only after 1950. The sedimentological and geochemical result confirm the actual unless of coarser fluvial supplies under the human activities leading the negative coastal sediment balance and the shoreline retreat as well.

  11. Evaluation of skill at simulating heatwave and heat-humidity indices in Global and Regional Climate Models

    Science.gov (United States)

    Goldie, J. K.; Alexander, L. V.; Lewis, S. C.; Sherwood, S. C.

    2017-12-01

    A wide body of literature now establishes the harm of extreme heat on human health, and work is now emerging on the projection of future health impacts. However, heat-health relationships vary across different populations (Gasparrini et al. 2015), so accurate simulation of regional climate is an important component of joint health impact projection. Here, we evaluate the ability of nine Global Climate Models (GCMs) from CMIP5 and the NARCliM Regional Climate Model to reproduce a selection of 15 health-relevant heatwave and heat-humidity indices over the historical period (1990-2005) using the Perkins skill score (Perkins et al. 2007) in five Australian cities. We explore the reasons for poor model skill, comparing these modelled distributions to both weather station observations and gridded reanalysis data. Finally, we show changes in the modelled distributions from the highest-performing models under RCP4.5 and RCP8.5 greenhouse gas scenarios and discuss the implications of simulated heat stress for future climate change adaptation. ReferencesGasparrini, Antonio, Yuming Guo, Masahiro Hashizume, Eric Lavigne, Antonella Zanobetti, Joel Schwartz, Aurelio Tobias, et al. "Mortality Risk Attributable to High and Low Ambient Temperature: A Multicountry Observational Study." The Lancet 386, no. 9991 (July 31, 2015): 369-75. doi:10.1016/S0140-6736(14)62114-0. Perkins, S. E., A. J. Pitman, N. J. Holbrook, and J. McAneney. "Evaluation of the AR4 Climate Models' Simulated Daily Maximum Temperature, Minimum Temperature, and Precipitation over Australia Using Probability Density Functions." Journal of Climate 20, no. 17 (September 1, 2007): 4356-76. doi:10.1175/JCLI4253.1.

  12. The buffering-out effect and phase separation in aqueous solutions of EPPS buffer with 1-propanol, 2-propanol, or 2-methyl-2-propanol at T = 298.15 K

    International Nuclear Information System (INIS)

    Taha, Mohamed; Teng, Han-Lan; Lee, Ming-Jer

    2012-01-01

    Highlights: ► Buffering-out is a new liquid–liquid phase separation containing biological buffer. ► EPPS buffer-induced phase separation of aqueous solutions of aliphatic alcohols. ► Phase diagrams of EPPS + water + 1-propanol/2-propanol/2-methyl-2-propanol are studied. ► EPPS breaks the 1-propanol + water and 2-methyl-2-propanol + water azeotropes. ► The (liquid + liquid) equilibria can be well correlated by the NRTL model. - Abstract: Buffering-out is a new liquid–liquid phase separation phenomenon observed in mixtures containing a buffer as a mass separating agent. The (liquid + liquid) equilibrium (LLE) and (solid + liquid + liquid) equilibrium (SLLE) data were measured for the ternary systems {3-[4-(2-hydroxyethyl)piperazin-1-yl]propanesulfonic acid (EPPS) buffer + 1-propanol, 2-propanol, or 2-methyl-2-propanol + water} at T = 298.15 K under atmospheric pressure. The phase boundary data were fitted to an empirical equation relating to the concentrations of organic solvent and buffer. The effective excluded volume (EEV) values of EPPS were obtained from the phase boundary data. The phase-separation abilities of the investigated aliphatic alcohols were discussed. The reliability of the experimental tie-lines was satisfactorily confirmed by the Othmer–Tobias correlation. The experimental tie-lines data for the ternary systems have been correlated using the NRTL activity coefficient model. The separation of these aliphatic alcohols from their azeotropic aqueous mixtures is of particular interest to industrial process. The addition of the EPPS as an auxiliary agent breaks the (1-propanol + water) and (2-methyl-2-propanol + water) azeotropes. The possibility of using the new phase separation systems in the extraction process is demonstrated by using different dyestuffs.

  13. (Liquid + liquid), (solid + liquid), and (solid + liquid + liquid) equilibria of systems containing cyclic ether (tetrahydrofuran or 1,3-dioxolane), water, and a biological buffer MOPS

    International Nuclear Information System (INIS)

    Altway, Saidah; Taha, Mohamed; Lee, Ming-Jer

    2015-01-01

    Graphical abstract: - Highlights: • MOPS buffer induced liquid phase splitting for mixtures of water with THF or 1,3-dioxolane. • Phase boundaries of LLE, SLE, and SLLE were determined experimentally. • Tie-lines at LLE and at SLLE were also measured. • Phase diagrams of MOPS + water + THF or 1,3-dioxolane are prepared. • LLE tie-line data are correlated satisfactorily with the NRTL model. - Abstract: Two liquid phases were formed as the addition of a certain amount of biological buffer 3-(N-morpholino)propane sulfonic acid (MOPS) in the aqueous solutions of tetrahydrofuran (THF) or 1,3-dioxolane. To evaluate the feasibility of recovering the cyclic ethers from their aqueous solutions with the aid of MOPS, we determined experimentally the phase diagrams of the ternary systems of {cyclic ether (THF or 1,3-dioxolane) + water + MOPS} at T = 298.15 K under atmospheric pressure. In this study, the solubility data of MOPS in water and in the mixed solvents of water/cyclic ethers were obtained from the results of a series of density measurements, while the (liquid + liquid) and the (solid + liquid + liquid) phase boundaries were determined by visually inspection. Additionally, the tie-line results for (liquid + liquid) equilibrium (LLE) and for (solid + liquid + liquid) equilibrium (SLLE) were measured using an analytical method. The reliability of the experimental LLE tie-line results data was validated by using the Othmer–Tobias correlation. These LLE tie-line values were correlated well with the NRTL model. The phase diagrams obtained from this study reveal that MOPS is a feasible green auxiliary agent to recover the cyclic ethers from their aqueous solutions, especially for 1,3-dioxolane

  14. Governança e Cooperação em Arranjos Produtivos Locais: Um Estudo de Múltiplos Casos em Sergipe

    Directory of Open Access Journals (Sweden)

    Aline de Aragão Zambrana

    2013-03-01

    Full Text Available Os Arranjos Produtivos Locais (APLs têm se apresentado como estratégia para as micro, pequenas e médias empresas aumentarem suas chances de sobrevivência e superarem as barreiras para seu crescimento. O presente estudo pretendeu analisar como a governança e a cooperação entre os agentes institucionais e econômicos podem influenciar o desenvolvimento de APLs no Estado de Sergipe. Foram utilizados os procedimentos metodológicos relativos ao estudo de casos múltiplos. O nível de análise considerado foi o APL, e a unidade de análise foram os agentes institucionais e os agentes econômicos. Foram realizadas 32 entrevistas semiestruturadas com os agentes dos APLs de Sergipe. Com base na análise dos casos, observouse que nos APLs estudados predominam as micro e pequenas empresas com baixo nível tecnológico e que utilizam os mercados local/regional e regional/nacional como destinos da produção. Os maiores aglomerados, em número de unidades produtivas existentes e de empregos formais gerados, foram o de Cerâmica Vermelha de Itabaianinha e o de Confecções de Tobias Barreto. A natureza da coordenação e articulação entre as empresas localizadas tende a ser baixa e é caracterizada por competição descomedida e baixos níveis de confiança. Constatou-se que a prática da concorrência desleal tem provocado o isolamento dos empresários e reduzido a probabilidade de ocorrência de ações conjuntas.

  15. Fixed combination of bimatoprost and timolol in patients with primary open-angle glaucoma or ocular hypertension with inadequate IOP adjustment

    Directory of Open Access Journals (Sweden)

    Gerrett Brief

    2010-09-01

    Full Text Available Gerrett Brief1, Tobias Lammich2, Edgar Nagel3, Sabine Pfennigsdorf4, Christoph W Spraul5, Selwyn Ho61Facharzt für Augenheilkunde, Dortmund, Germany; 2Neubrandenburg, Germany; 3Augenarztpraxis Rudolstadt, Germany; 4Polch, Germany; 5Geiselhart, Ulm, Germany; 6Allergan Europe, Marlow, UKObjective: To assess the efficacy and tolerability of a fixed combination of bimatoprost and timolol (BTFC in a large patient sample in a clinical setting.Methods: In this multicenter, observational, noncontrolled, open-label study, patients (n = 1862 with primary open-angle glaucoma or ocular hypertension were treated with BTFC. Assessments were made at baseline, six weeks, and three months.Results: Prior to starting BTFC, 92.3% of patients were taking other ocular hypotensive medications. In the overall group at three months, mean intraocular pressure was reduced from baseline (21.7 ± 4.5 mmHg and 21.8 ± 4.9 mmHg for the right and left eye, respectively to 16.1 ± 3.0 mmHg for each eye (P < 0.0001. The majority of patients (92% reported no adverse events. The most commonly reported adverse events (in >1% of patients were eye irritation, and ocular and conjunctival hyperemia. Adherence to treatment was generally better than (35.4% or the same as (57.5% with prior therapy. BTFC tolerability was rated as excellent or good by 92.3% of physicians and 85.8% of patients.Conclusions: In a large group of patients with primary open-angle glaucoma or ocular hypertension, treatment with BTFC was associated with consistent reductions in IOP, improved adherence to treatment, and good tolerability.Keywords: bimatoprost, timolol, intraocular pressure, fixed combination, glaucoma

  16. Piano training in youths with hand motor impairments after damage to the developing brain

    Directory of Open Access Journals (Sweden)

    Lampe R

    2015-08-01

    Full Text Available Renée Lampe,1,* Anna Thienel,2 Jürgen Mitternacht,1 Tobias Blumenstein,1 Varvara Turova,1 Ana Alves-Pinto1,* 1Research Unit for Paediatric Neuroorthopaedics and Cerebral Palsy, Orthopaedics Department, Klinikum Rechts der Isar, Technische Universität München, 2Department Sonderpädagogik, Ludwig Maximilians-Universität München, Munich, Germany *These authors contributed equally to this work Abstract: Damage to the developing brain may lead to impairment of the hand motor function and negatively impact on patients’ quality of life. Development of manual dexterity and finger and hand motor function may be promoted by learning to play the piano. The latter brings together music with the intensive training of hand coordination and fine finger mobility. We investigated if learning to play the piano helped to improve hand motor skills in 18 youths with hand motor disorders resulting from damage during early brain development. Participants trained 35–40 minutes twice a week for 18 months with a professional piano teacher. With the use of a Musical Instrument Digital Interface piano, the uniformity of finger strokes could be objectively assessed from the timing of keystrokes. The analysis showed a significant improvement in the uniformity of keystrokes during the training. Furthermore, the youths showed strong motivation and engagement during the study. This is nevertheless an open study, and further studies remain needed to exclude effects of growth and concomitant therapies on the improvements observed and clarify which patients will more likely benefit from learning to play the piano. Keywords: manual skill, cerebral palsy, neurodevelopmental disorder, music, rehabilitation

  17. Gross and fine motor function in fibromyalgia and chronic fatigue syndrome

    Directory of Open Access Journals (Sweden)

    Rasouli O

    2017-02-01

    Full Text Available Omid Rasouli,1,2 Egil A Fors,3 Petter Chr Borchgrevink,4,5 Fredrik Öhberg,6 Ann-Katrin Stensdotter1 1Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; 2Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; 3Department of Public Health and Nursing, General Practice Research Unit, Norwegian University of Science and Technology, Trondheim, Norway; 4Department of Circulation and Medical Imaging, Pain and Palliation Research Group, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; 5National Competence Centre for Complex Symptom Disorders, St. Olav’s University Hospital, Trondheim, Norway; 6Department of Radiation Sciences, Biomedical Engineering, Umeå University, Umeå, Sweden Purpose: This paper aimed to investigate motor proficiency in fine and gross motor function, with a focus on reaction time (RT and movement skill, in patients with fibromyalgia (FM and chronic fatigue syndrome (CFS compared to healthy controls (HC.Methods: A total of 60 individuals (20 CFS, 20 FM, and 20 HC, age 19–49 years, participated in this study. Gross motor function in the lower extremity was assessed using a RT task during gait initiation in response to an auditory trigger. Fine motor function in the upper extremity was measured during a precision task (the Purdue Pegboard test where the number of pins inserted within 30 s was counted.Results: No significant differences were found between FM and CFS in any parameters. FM and CFS groups had significantly longer RT than HC in the gait initiation (p=0.001, and p=0.004 respectively. In the Purdue Pegboard test, 20% in the FM group, 15% in the CFS groups, and 0% of HC group, scored below the threshold of the accepted performance. However, there were no

  18. Economic impact of longer battery life of cardiac resynchronization therapy defibrillators in Sweden

    Directory of Open Access Journals (Sweden)

    Gadler F

    2016-10-01

    Full Text Available Fredrik Gadler,1 Yao Ding,2 Nathalie Verin,3 Martin Bergius,4 Jeffrey D Miller,5 Gregory M Lenhart,5 Mason W Russell5 1Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden; 2Truven Health Analytics, an IBM Company, Bethesda, MD, USA; 3Boston Scientific Corporation, Hemel Hempstead, Hertfordshire, UK; 4Boston Scientific Nordic AB, Helsingborg, Sweden; 5Truven Health Analytics, an IBM Company, Cambridge, MA, USA Objective: The objective of this study was to quantify the impact that longer battery life of cardiac resynchronization therapy defibrillator (CRT-D devices has on reducing the number of device replacements and associated costs of these replacements from a Swedish health care system perspective.Methods: An economic model based on real-world published data was developed to estimate cost savings and avoided device replacements for CRT-Ds with longer battery life compared with devices with industry-standard battery life expectancy. Base-case comparisons were performed among CRT-Ds of three manufacturers – Boston Scientific Corporation, St. Jude Medical, and Medtronic – over a 6-year time horizon, as per the available clinical data. As a sensitivity analysis, we evaluated CRT-Ds as well as single-chamber implantable cardioverter defibrillator (ICD-VR and dual-chamber implantable cardioverter defibrillator (ICD-DR devices over a longer 10-year period. All costs were in 2015 Swedish Krona (SEK discounted at 3% per annum.Results: Base-case analysis results show that up to 603 replacements and up to SEK 60.4 million cumulative-associated costs could be avoided over 6 years by using devices with extended ­battery life. The pattern of savings over time suggests that savings are modest initially but increase rapidly beginning in the third year of follow-up with each year’s cumulative savings two to three times the previous year. Evaluating CRT-D, ICD-VR, and ICD-DR devices together over a longer 10-year period, the

  19. Severe forms of fibromyalgia with acute exacerbation of pain: costs, comorbidities, and length of stay in inpatient care

    Directory of Open Access Journals (Sweden)

    Romeyke T

    2017-06-01

    Full Text Available Tobias Romeyke,1,2 Elisabeth Noehammer,1 Hans Christoph Scheuer,2 Harald Stummer1,3 1Institute for Management and Economics in Health Care, University of Health Sciences, Medical Informatics and Technology (UMIT, Hall in Tirol, Austria; 2Waldhausklinik Deuringen, Acute Hospital for Internal Medicine, Pain Therapy, Complementary, and Individualized Patient-Centered Medicine, Stadtbergen, Germany; 3Institute for Management and Innovation in Healthcare, University Schloss Seeburg, Seekirchen/Wallersee, Austria Background and purpose: As a disease of the musculoskeletal system, fibromyalgia is becoming increasingly important, because of the direct and indirect costs to health systems. The purpose of this study of health economics was to obtain information about staff costs differentiated by service provider, and staff and material costs of the nonmedical infrastructure in inpatient care.Patients and methods: This study looked at 263 patients who received interdisciplinary inpatient treatment for severe forms of fibromyalgia with acute exacerbation of pain between 2011 and 2014. Standardized cost accounting and an analysis of additional diagnoses were performed.Results: The average cost per patient was €3,725.84, with staff and material costs of the nonmedical infrastructure and staff costs of doctors and nurses accounting for the highest proportions of the costs. Each fibromyalgia patient had an average of 6.1 additional diagnoses.Conclusion: Severe forms of fibromyalgia are accompanied by many concomitant diseases and associated with both high clinical staff costs and high medical and nonmedical infrastructure costs. Indication-based cost calculations provide important information for health policy and hospital managers if they include all elements that incur costs in both a differentiated and standardized way. Keywords: fibromyalgia, DRG, cost, length of stay, comorbidities, interdisciplinary care, inpatient care, musculoskeletal, pain

  20. Ionic liquid 1-hexyl-3-methylimidazolium hexafluorophosphate, an efficient solvent for extraction of acetone from aqueous solutions

    International Nuclear Information System (INIS)

    Saien, Javad; Badieh, Marjan Mohammadi Sarab; Norouzi, Mahdi; Salehzadeh, Sadegh

    2015-01-01

    Highlights: • The use of HMIMPF_6 as a green ionic was feasible in the extraction of acetone from water. • The binodal curves were determined by cloud point measurement method. • High level separation factor of acetone between the ionic liquid and water were achieved. • The thermodynamic properties of HMIMPF_6 were obtained by the Density Functional Theory calculations. • The NRTL and UNIQUAC models were applied satisfactorily to correlate the equilibrium data. - Abstract: (Liquid + liquid) equilibrium (LLE) of the chemical system of {water + acetone + 1-Hexyl-3-methylimidazolium hexafluorophosphate (HMIMPF_6) ionic liquid} was studied at different temperatures of (293.2, 298.2 and 303.2) K and under atmospheric pressure of 81.5 kPa. The results show that HMIMPF_6 provides the acetone distribution coefficient and separation factor values within (0.8813 to 1.2351) and (3.0 to 54.4), respectively; indicating the high capability of the ionic liquid for extraction of acetone from aqueous solutions. In most cases, acetone solubility in the ionic liquid is higher than in water, especially at higher solute concentrations. Meanwhile, higher separation factor is relevant to the lower temperature due to lower (water + ionic liquid) miscibility. The consistency of tie line data, at each temperature, was examined with Othmer–Tobias correlation. The values were nicely reproduced with the well-known NRTL and UNIQUAC models. Accordingly, the required thermodynamic properties of HMIMPF_6 were obtained by the Density Functional Theory (DFT) calculations, carried out at the M06/6-311++G"∗"∗ level of theory. The root mean square deviations (RMSD) between experimental and model concentration values were 0.0192 and 0.0255, respectively; indicating close agreement of the both models.

  1. Characteristics of dune-paleosol-sequences in Fuerteventura. - What should be questioned?

    Science.gov (United States)

    Faust, Dominik; Willkommen, Tobias; Yanes, Yurena; Richter, David; Zöller, Ludwig

    2013-04-01

    Characteristics of dune-paleosol-sequences in Fuerteventura. - What should be questioned? Dominik Faust, TU Dresden, Germany Tobias Willkommen, TU Dresden, Germany Yurena Yanes, CSIC Granada/Cincinatti, Spain/USA David Richter, TU Dresden, Germany Ludwig Zöller, Uni Bayreuth, Germany The northern part of Fuerteventura is characterized by large dune fields. We investigated dune-paleosol-sequences in four pits to establish a robust stratigraphy and to propose a standard section. An interaction of processes like dune formation, soil formation and redeposition of soils and sand are most important to understand the principles of landscape development in the study area. To our mind a process cycle seem to be important: First climbing-dunes are formed by sand of shelf origin. Then soil formation could have taken place. Soil and/or sand were then eroded and deposited at toe slope position. This material in turn is the source of new sand supply and dune formation. The described cycle may be repeated several times and this ping-pong-process holds on. The results are sections composed of dune layers, paleosols and colluvial material interbedded. Fundamental questions still remain unanswered: Is climate change responsable for changes in process combination (e.g. from dune formation to soil formation)? Or are these features due to divergence phenomenon, where different effects/results (dune and soils) may be linked to similar causes (here: climate)? Assuming that different features (soils and dunes) were formed under one climate, increasing soil forming intensity could be mainly a function of decreasing sand supply. This in turn could be caused by reduced sand production (s. ZECH et al. accepted). However geochemical data and mollusc assemblages point to changing environments in space and even climate modifications in time.

  2. Galileo's Medicean Moons (IAU S269)

    Science.gov (United States)

    Barbieri, Cesare; Chakrabarti, Supriya; Coradini, Marcello; Lazzarin, Monica

    2010-11-01

    Preface; 1. Galileo's telescopic observations: the marvel and meaning of discovery George V. Coyne, S. J.; 2. Popular perceptions of Galileo Dava Sobel; 3. The slow growth of humility Tobias Owen and Scott Bolton; 4. A new physics to support the Copernican system. Gleanings from Galileo's works Giulio Peruzzi; 5. The telescope in the making, the Galileo first telescopic observations Alberto Righini; 6. The appearance of the Medicean Moons in 17th century charts and books. How long did it take? Michael Mendillo; 7. Navigation, world mapping and astrometry with Galileo's moons Kaare Aksnes; 8. Modern exploration of Galileo's new worlds Torrence V. Johnson; 9. Medicean Moons sailing through plasma seas: challenges in establishing magnetic properties Margaret G. Kivelson, Xianzhe Jia and Krishan K. Khurana; 10. Aurora on Jupiter: a magnetic connection with the Sun and the Medicean Moons Supriya Chakrabarti and Marina Galand; 11. Io's escaping atmosphere: continuing the legacy of surprise Nicholas M. Schneider; 12. The Jovian Rings Wing-Huen Ip; 13. The Juno mission Scott J. Bolton and the Juno Science Team; 14. Seeking Europa's ocean Robert T. Pappalardo; 15. Europa lander mission: a challenge to find traces of alien life Lev Zelenyi, Oleg Korablev, Elena Vorobyova, Maxim Martynov, Efraim L. Akim and Alexander Zakahrov; 16. Atmospheric moons Galileo would have loved Sushil K. Atreya; 17. The study of Mercury Louise M. Prockter and Peter D. Bedini; 18. Jupiter and the other giants: a comparative study Thérèse Encrenaz; 19. Spectroscopic and spectrometric differentiation between abiotic and biogenic material on icy worlds Kevin P. Hand, Chris McKay and Carl Pilcher; 20. Other worlds, other civilizations? Guy Consolmagno, S. J.; 21. Concluding remarks Roger M. Bonnet; Posters; Author index; Object index.

  3. Heavy ion-induced lesions in DNA: A theoretical model for the initial induction of DNA strand breaks and chromatin breaks

    International Nuclear Information System (INIS)

    Schmidt, J.B.

    1993-01-01

    A theoretical model has been developed and used to calculate yields and spatial distributions of DNA strand breaks resulting from the interactions of heavy ions with chromatin in aqueous systems. The three dimensional spatial distribution of ionizing events has been modeled for charged particles as a function of charge and velocity. Chromatin has been modeled as a 30 nm diameter solenoid of nucleosomal DNA. The Monte Carlo methods used by Chatterjee et al. have been applied to DNA in a chromatin conformation. Refinements to their methods include: a combined treatment of primary and low energy (<2 keV) secondary electron interactions, an improved low energy delta ray model, and the combined simulation of direct energy deposition on the DNA and attack by diffusing hydroxyl radicals. Individual particle tracks are treated independently, which is assumed to be applicable to low fluence irradiations in which multiple particle effects are negligible. Single strand break cross section open-quotes hooksclose quotes seen in experiments at very high LET appear to be due to the collapsing radial extent of the track, as predicted in the open-quotes deep sieveclose quotes hypothesis proposed by Tobias et al. Spatial distributions of lesions produced by particles have been found to depend on chromatin structure. In the future, heavy ions may be used as a tool to probe the organization of DNA in chromatin. A Neyman A-binomial variation of the open-quotes cluster modelclose quotes for the distribution of chromatin breaks per irradiated cell has been theoretically tested. The model includes a treatment of the chromatin fragment detection technique's resolution, which places a limitation on the minimum size of fragments which can be detected. The model appears to fit some of the experimental data reasonably well. However, further experimental and theoretical refinements are desirable

  4. The evolution of the upright posture and gait—a review and a new synthesis

    Science.gov (United States)

    Niemitz, Carsten

    2010-03-01

    During the last century, approximately 30 hypotheses have been constructed to explain the evolution of the human upright posture and locomotion. The most important and recent ones are discussed here. Meanwhile, it has been established that all main hypotheses published until the last decade of the past century are outdated, at least with respect to some of their main ideas: Firstly, they were focused on only one cause for the evolution of bipedality, whereas the evolutionary process was much more complex. Secondly, they were all placed into a savannah scenario. During the 1990s, the fossil record allowed the reconstruction of emerging bipedalism more precisely in a forested habitat (e.g., as reported by Clarke and Tobias (Science 269:521-524, 1995) and WoldeGabriel et al. (Nature 412:175-178, 2001)). Moreover, the fossil remains revealed increasing evidence that this part of human evolution took place in a more humid environment than previously assumed. The Amphibian Generalist Theory, presented first in the year 2000, suggests that bipedalism began in a wooded habitat. The forests were not far from a shore, where our early ancestor, along with its arboreal habits, walked and waded in shallow water finding rich food with little investment. In contrast to all other theories, wading behaviour not only triggers an upright posture, but also forces the individual to maintain this position and to walk bipedally. So far, this is the only scenario suitable to overcome the considerable anatomical and functional threshold from quadrupedalism to bipedalism. This is consistent with paleoanthropological findings and with functional anatomy as well as with energetic calculations, and not least, with evolutionary psychology. The new synthesis presented here is able to harmonise many of the hitherto competing theories.

  5. Process Damping Parameters

    International Nuclear Information System (INIS)

    Turner, Sam

    2011-01-01

    The phenomenon of process damping as a stabilising effect in milling has been encountered by machinists since milling and turning began. It is of great importance when milling aerospace alloys where maximum surface speed is limited by excessive tool wear and high speed stability lobes cannot be attained. Much of the established research into regenerative chatter and chatter avoidance has focussed on stability lobe theory with different analytical and time domain models developed to expand on the theory first developed by Trusty and Tobias. Process damping is a stabilising effect that occurs when the surface speed is low relative to the dominant natural frequency of the system and has been less successfully modelled and understood. Process damping is believed to be influenced by the interference of the relief face of the cutting tool with the waveform traced on the cut surface, with material properties and the relief geometry of the tool believed to be key factors governing performance. This study combines experimental trials with Finite Element (FE) simulation in an attempt to identify and understand the key factors influencing process damping performance in titanium milling. Rake angle, relief angle and chip thickness are the variables considered experimentally with the FE study looking at average radial and tangential forces and surface compressive stress. For the experimental study a technique is developed to identify the critical process damping wavelength as a means of measuring process damping performance. For the range of parameters studied, chip thickness is found to be the dominant factor with maximum stable parameters increased by a factor of 17 in the best case. Within the range studied, relief angle was found to have a lesser effect than expected whilst rake angle had an influence.

  6. Enhancement of the Microscopy Facilities at the NSLS X1A Beamline

    International Nuclear Information System (INIS)

    Jacobson, Chris

    1999-01-01

    As originally proposed, the authors constructed a new Scanning Transmission X-ray Microscope, STXM IV. The design and construction was led by Chris Jacobsen, and involved graduate students Michael Feser, Mary Carlucci-Dayton and Tobias Beetz. This microscope has the following new features: It has a new and improved high resolution scanning stage that should make it possible to perform higher resolution imaging without distortions. Preliminary results indicate that the stage performs as designed. It has an enclosure that can be evacuated and backfilled with helium. This makes it possible to perform imaging in the neighborhood of the nitrogen and oxygen edges without interference from residual air. It has a motorized detector stage for easy interchange of detectors and alignment microscope. We expect to use this to align the new segmented detector which makes it possible to perform brightfield and dark field microscopy simultaneously, and to record images in differential phase contrast as well. The microscope is located upstream of cryoSTXM, the instrument we use to examine specimens in a frozen hydrated state. The design of STXM IV is such that it makes it quick and easy to switch between STXM IV and cryo-STXM operations and vice versa. IEEE488 based control electronics provides multiple channels of data collection. The microscope is run from a LINUX PC with all new software, developed in-house. The stages for the zone plate and the order sorting aperture (OSA) have kinematic mounts. This way different sets of zone plates (optimized for different wavelengths and working distances) can be exchanged without the need for complete realignment of the instrument. The enclosure can be used as a glove-box, making it possible to examine specimens which require anaerobic handling

  7. Similar long-term survival of consecutive in-hospital and out-of-hospital cardiac arrest patients treated with targeted temperature management

    Directory of Open Access Journals (Sweden)

    Engsig M

    2016-11-01

    Full Text Available Magaly Engsig,1 Helle Søholm,2 Fredrik Folke,3,4 Peter J Gadegaard,1 Julie Therese Wiis,5 Rune Molin,6 Thomas Mohr,1 Frederik N Engsig7 1Department of Anaesthesiology and Intensive Care, Copenhagen University Hospital, Hellerup, 2Department of Cardiology, Copenhagen University Hospital, Herlev, 3Department of Cardiology, Copenhagen University Hospital, Hellerup, 4Pre-Hospital Emergency Medical Services, Capital Region of Denmark, Ballerup, 5Department of Intensive Care, Copenhagen University Hospital, Copenhagen, 6Department of Anaesthesiology, Copenhagen University Hospital, Hillerød, 7Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark Objective: The long-term survival of in-hospital cardiac arrest (IHCA patients treated with targeted temperature management (TTM is poorly described. The aim of this study was to compare the outcomes of consecutive IHCA with out-of-hospital cardiac arrest (OHCA patients treated with TTM. Design, setting, and patients: Retrospectively collected data on all consecutive adult patients treated with TTM at a university tertiary heart center between 2005 and 2011 were analyzed. Measurements: Primary endpoints were survival to hospital discharge and long-term survival. Secondary endpoint was neurological outcome assessed using the Pittsburgh cerebral performance category (CPC. Results: A total of 282 patients were included in this study; 233 (83% OHCA and 49 (17% IHCA. The IHCA group presented more often with asystole, received bystander cardiopulmonary resuscitation (CPR in all cases, and had shorter time to return of spontaneous circulation (ROSC. Survival to hospital discharge was 54% for OHCA and 53% for IHCA (adjusted odds ratio 0.98 [95% confidence interval {CI}; 0.43–2.24]. Age ≤60 years, bystander CPR, time to ROSC ≤10 min, and shockable rhythm at presentation were associated with survival to hospital discharge. Good neurologic outcome among survivors was achieved by 86

  8. Frequency and clinical relevance of human bocavirus infection in acute exacerbations of chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Felix C Ringshausen

    2009-02-01

    Full Text Available Felix C Ringshausen1, Ai-Yui M Tan1, Tobias Allander2, Irmgard Borg1, Umut Arinir1, Juliane Kronsbein1, Barbara M Hauptmeier1, Gerhard Schultze-Werninghaus1, Gernot Rohde11Clinical Research Group “Significance of viral infections in chronic respiratory diseases of children and adults,” University Hospital Bergmannsheil, Department of Internal Medicine III–Pneumology, Allergology and Sleep Medicine, Bochum, Germany; 2Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, and Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, SwedenObjective: Human bocavirus (HBoV is a recently discovered parvovirus associated with acute respiratory tract infections in children. The objective of the present study was to determine the frequency and clinical relevance of HBoV infection in adult patients with acute exacerbation of chronic obstructive pulmonary disease (AE-COPD.Methods: We retrospectively tested 212 COPD patients, 141 (66.5% with AE-COPD and 71 (33.5% with stable disease, of whom nasal lavage and induced sputum had been obtained for the presence of HBoV deoxyribonucleic acid (DNA. The specificity of positive polymerase chain reaction results was confirmed by sequencing.Results: Two hundred two of 212 patients for whom PCR results were available both for nasal lavage and induced sputum samples were eligible for data analysis. HBoV DNA was detected in three patients (1.5%. Of those, only one patient had AE-COPD. Thus, the frequency of HBoV infection demonstrated to be low in both AE-COPD (0.8% and stable COPD (2.9%. HBoV was found in two sputum and one nasal lavage sample in different patients, respectively. Sequencing revealed >99% sequence identity with the reference strain.Conclusion: HBoV detection was infrequent. Since we detected HBoV in both upper and lower respiratory tract specimens and in AE-COPD as well as stable disease, a major role of HBoV infection in adults with AE-COPD is unlikely

  9. Solubility and phase separation of 4-morpholinepropanesulfonic acid (MOPS), and 3-morpholino-2-hydroxypropanesulfonic acid (MOPSO) in aqueous 1,4-dioxane and ethanol solutions

    International Nuclear Information System (INIS)

    Taha, Mohamed; Lee, Ming-Jer

    2011-01-01

    Highlights: → Solubilities of MOPS and MOPSO buffers in aqueous 1,4-dioxane and ethanol solutions. → We found that MOPS-induced phase separation of aqueous solution of 1,4-dioxane. → The phase diagram of (MOPS + water + 1,4-dioxane) system at 298.15 K is documented. → The tie-lines within the two-liquid phase region were also determined at 298.15 K. → The effective excluded volume theory was applied to correlate the binodal LLE data. - Abstract: The buffers 4-morpholinepropanesulfonic acid (MOPS) and 3-morpholino-2-hydroxypropanesulfonic acid (MOPSO) are useful biological zwitterionic buffers within the pH range of 6.5 to 7.9 and 6.2 to 7.6, respectively. The solubilities of these buffers were determined in binary mixtures (1,4-dioxane + water) and (ethanol + water) at T = 298.15 K by using the results of density measurements. It has been observed that MOPS induced liquid-liquid phase splitting for the mixtures of 40% to 90% (w/w) 1,4-dioxane in water. The two-liquid phase formation was visualized with disperse orange 25. The phase equilibrium boundaries, including the regions of one liquid, two liquids, (one liquid + one solid) and (two liquids + one solid), for the (MOPS + water + 1,4-dioxane) system have been determined experimentally at T = 298.15 K. The tie lines of the (liquid + liquid) equilibrium were also measured. The Othmer-Tobias and Bancroft equation were used to evaluate the reliability of the tie-line data. The binodal curve was fitted to an empirical equation and the effective excluded volume (EEV) model. The apparent free energies of transfer (ΔG tr ' ) of MOPS and MOPSO from water to 1,4-dioxane and ethanol solutions have been calculated from the solubility data. These ΔG tr ' values were compared with those of some related biological buffers (TRIS, TAPS, TAPSO, and TABS). Furthermore, we also calculated the contribution of transfer free energies (Δg tr ' ) of -OH group from water to 1,4-dioxane and ethanol solutions.

  10. Analytical strategies for discovery and replication of genetic effects in pharmacogenomic studies

    Directory of Open Access Journals (Sweden)

    Kohler JR

    2014-08-01

    Full Text Available Jared R Kohler, Tobias Guennel, Scott L MarshallBioStat Solutions, Inc., Frederick, MD, USAAbstract: In the past decade, the pharmaceutical industry and biomedical research sector have devoted considerable resources to pharmacogenomics (PGx with the hope that understanding genetic variation in patients would deliver on the promise of personalized medicine. With the advent of new technologies and the improved collection of DNA samples, the roadblock to advancements in PGx discovery is no longer the lack of high-density genetic information captured on patient populations, but rather the development, adaptation, and tailoring of analytical strategies to effectively harness this wealth of information. The current analytical paradigm in PGx considers the single-nucleotide polymorphism (SNP as the genomic feature of interest and performs single SNP association tests to discover PGx effects – ie, genetic effects impacting drug response. While it can be straightforward to process single SNP results and to consider how this information may be extended for use in downstream patient stratification, the rate of replication for single SNP associations has been low and the desired success of producing clinically and commercially viable biomarkers has not been realized. This may be due to the fact that single SNP association testing is suboptimal given the complexities of PGx discovery in the clinical trial setting, including: 1 relatively small sample sizes; 2 diverse clinical cohorts within and across trials due to genetic ancestry (potentially impacting the ability to replicate findings; and 3 the potential polygenic nature of a drug response. Subsequently, a shift in the current paradigm is proposed: to consider the gene as the genomic feature of interest in PGx discovery. The proof-of-concept study presented in this manuscript demonstrates that genomic region-based association testing has the potential to improve the power of detecting single SNP or

  11. Safety and efficacy of nurse-controlled analgesia in patients less than 1 year of age

    Directory of Open Access Journals (Sweden)

    Walia H

    2016-06-01

    Full Text Available Hina Walia,1 Dmitry Tumin,1 Sharon Wrona,1 David Martin,1,2 Tarun Bhalla,1,2 Joseph D Tobias,1-3 1Department of Anesthesiology and Pain Medicine, Nationwide Children’s Hospital, 2Department of Anesthesiology and Pain Medicine, 3Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA Background: The management of acute pain presents unique challenges in the younger pediatric population. Although patient-controlled devices are frequently used in patients ≥6 years of age, alternative modes of analgesic delivery are needed in infants.Objective: To examine the safety and efficacy of nurse-controlled analgesia (NCA in neonates less than 1 year of age.Methods: Data from patients <1 year of age receiving NCA as ordered by the Acute Pain Service at our institution were collected over a 5-year period and reviewed retrospectively. The primary outcomes were activation of the institution’s Rapid Response Team (RRT or Code Blue, signifying severe adverse events. Pain score after NCA initiation was a secondary outcome.Results: Among 338 girls and 431 boys, the most common opioid used for NCA was fentanyl, followed by morphine and hydromorphone. There were 39 (5% cases involving RRT or Code Blue activation, of which only one (Code Blue was activated due to a complication of NCA (apnea. Multivariable logistic regression demonstrated morphine NCA to be associated with greater odds of RRT activation (OR=3.29, 95% CI=1.35, 8.03, P=0.009 compared to fentanyl NCA. There were no statistically significant differences in pain scores after NCA initiation across NCA agents.Conclusion: NCA is safe in neonates and infants, with comparable efficacy demonstrated for the three agents used. The elevated incidence of RRT activation in patients receiving morphine suggests caution in its use and consideration of alternative agents in this population. Keywords: nurse-controlled analgesia, pain medicine, Rapid Response Team

  12. Fibromyalgia with severe forms of progression in a multidisciplinary therapy setting with emphasis on hyperthermia therapy – a prospective controlled study

    Directory of Open Access Journals (Sweden)

    Romeyke T

    2014-12-01

    Full Text Available Tobias Romeyke, Hans Christoph Scheuer, Harald Stummer Department of Public Health and Health Technology Assessment, Division for Organizational Behavior Research and Workplace Health Promotion, University for Health Sciences, Medical Informatics and Technology, Vienna, Austria Introduction: Fibromyalgia syndrome (FMS is a multi-factorial disease involving physiological as well as psychological factors. The aim of the study was to investigate a multidisciplinary inpatient treatment with emphasis on hyperthermia therapy by patients with widespread pain.Materials and methods: The study involved 104 patients suffering from severely progressive FMS. A convenience sample and a prospective cohort design were used. The patients were treated in an acute hospital focusing on rheumatologic pain therapy and multidisciplinary complementary medicine. One patient group was treated with inclusion of hyperthermia therapy and the other group without. The therapy density (number of performed therapies per patient was determined for every patient. Functional capacity measured by the Hannover functional status questionnaire (Funktionsfragebogen Hannover and symptoms (von Zerssen complaint list were analyzed for both groups on admission and on discharge.Results: On admission, no significant difference could be established between control group (CG; multimodal without hyperthermia and hyperthermia group (HG; multimodal with hyperthermia (functional capacity, P=0.936. Functional capacity improved for the CG and the HG. On discharge, there was a significant difference between the two groups (functional capacity, P=0.039. There were no significant differences in fibromyalgia symptoms between CG (mean 41.8 and HG (mean 41.8 on their admission to hospital (P=0.988. On discharge, there was a significant difference (P=0.024 between the two groups (HG, mean 30.6; CG, mean 36.6. The inpatient therapy of patients with severely progressive fibromyalgia is characterized by a

  13. Use of complementary and alternative medicine before and after organ removal due to urologic cancer

    Directory of Open Access Journals (Sweden)

    Mani J

    2015-10-01

    Full Text Available Jens Mani,1 Eva Juengel,1 Ilhan Arslan,1 Georg Bartsch,1 Natalie Filmann,2 Hanns Ackermann,2 Karen Nelson,3 Axel Haferkamp,1 Tobias Engl,1,* Roman A Blaheta1,* 1Department of Urology, 2Institute of Biostatistics and Mathematical Modeling, 3Department of Vascular and Endovascular Surgery, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany *These authors contributed equally to this work Objective: Many patients use complementary and alternative medicine (CAM as primary treatment or symptom relief for a variety of illnesses. This study was designed to investigate the influence of surgical removal of a tumor-bearing urogenital organ on CAM use.Methods: From 2007 to 2011, 350 patients underwent major urological surgery for kidney, prostate, or bladder cancer at the Goethe-University Hospital, Frankfurt, Germany. Data from 172 patients (49%, who returned a questionnaire, were retrospectively evaluated using the hospital information system along with the questionnaire to objectify CAM use 2 years before and after surgery.Results: From the 172 patients returning questionnaires, 56 (33% used CAM before and/or after surgery and 116 (67% never used CAM. Of the 56 CAM users, 30 (54% used CAM presurgery and 53 (95% used CAM postsurgery, indicating a significant change of mind about CAM use. Patients of German nationality used CAM significantly more than patients of other nationalities. Higher educational status (high-school diploma or higher was a significant factor in favor of CAM use. The most common type of CAM used before/after surgery was an alternative medical system (63/49%, a manipulative and body-based method (50/19%, and a biological-based therapy (37/32%. Information about CAM, either provided by medical professionals or by other sources, was the main reason determining whether patients used CAM or not.Conclusion: The number of patients using CAM almost doubled after surgical removal of a cancer-bearing organ. Better awareness and

  14. A study on the efficacy and safety of combining dental surgery with tonsillectomy in pediatrics

    Directory of Open Access Journals (Sweden)

    Syed F

    2018-03-01

    Full Text Available Faizaan Syed,1 Joshua C Uffman,1,2 Dmitry Tumin,1 Catherine M Flaitz,3,4 Joseph D Tobias,1,2 Vidya T Raman1,2 1Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, 2Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, 3Department of Dentistry, Nationwide Children’s Hospital, 4Division of Dentistry, The Ohio State University College of Dentistry, Columbus, OH, USA Purpose: Few data exist on combining pediatric surgical procedures under a single general anesthetic encounter (general anesthesia. We compared perioperative outcomes of combining dental surgical procedures with tonsillectomy during one anesthetic vs separate encounters. Methods: We classified elective tonsillectomy ± adenoidectomy and restorative dentistry as combined (group C or separate (group S. Outcomes included anesthesia time, recovery duration, the need for overnight hospital stay, and postoperative complications. Results: Patients aged 4±1 years underwent tonsillectomy and dental surgery in combination (n=7 or separately (n=27. No differences were noted in total anesthesia time (C: median: 150, interquartile range [IQR]: 99, 165 vs S: median: 109, IQR: 92, 132; 95% CI of difference in median: –58, +10 minutes; P=0.115 and total recovery time (C: median: 54, IQR: 40, 108 vs S: median: 72, IQR: 58, 109; 95% CI of difference in median: –16, +48 minutes; P=0.307. The need for overnight stay (C: 4 of 7, S: 20 of 27; P=0.394 did not differ between the groups. No postoperative complications were noted in either group. Conclusion: These preliminary data support the potential feasibility of combining dental procedures with tonsillectomy during a single anesthetic encounter. Such care may not only reduce costs but also limit parental work absences and increase convenience for patient families. When compared with procedures performed separately, combined procedures did not result in increased morbidity or

  15. Effects of short-term piano training on measures of finger tapping, somatosensory perception and motor-related brain activity in patients with cerebral palsy

    Directory of Open Access Journals (Sweden)

    Alves-Pinto A

    2017-10-01

    Full Text Available Ana Alves-Pinto,1 Stefan Ehrlich,2 Gordon Cheng,2 Varvara Turova,1 Tobias Blumenstein,1 Renée Lampe1 1Research Unit of the Buhl-Strohmaier Foundation for Paediatric Neuroorthopaedics and Cerebral Palsy, Department of Orthopaedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; 2Chair for Cognitive Systems, Department of Electrical and Computer Engineering, Technical University of Munich, Munich, Germany Abstract: Playing a musical instrument demands the integration of sensory and perceptual information with motor processes in order to produce a harmonic musical piece. The diversity of brain mechanisms involved and the joyful character of playing an instrument make musical instrument training a potential vehicle for neurorehabilitation of motor skills in patients with cerebral palsy (CP. This clinical condition is characterized by motor impairments that can affect, among others, manual function, and limit severely the execution of basic daily activities. In this study, adolescents and adult patients with CP, as well as a group of typically developing children learned to play piano for 4 consecutive weeks, having completed a total of 8 hours of training. For ten of the participants, learning was supported by a special technical system aimed at helping people with sensorimotor deficits to better discriminate fingers and orient themselves along the piano keyboard. Potential effects of piano training were assessed with tests of finger tapping at the piano and tests of perception of vibratory stimulation of fingers, and by measuring neuronal correlates of motor learning in the absence of and after piano training. Results were highly variable especially among participants with CP. Nevertheless, a significant effect of training on the ability to perceive the localization of vibrations over fingers was found. No effects of training on the performance of simple finger tapping sequences at the piano or on motor

  16. Gabapentin for once-daily treatment of post-herpetic neuralgia: a review

    Directory of Open Access Journals (Sweden)

    Beal B

    2012-07-01

    Full Text Available Benjamin Beal,1 Tobias Moeller-Bertram,1,2 Jan M Schilling,1 Mark S Wallace11Division of Pain Medicine, Department of Anesthesiology, University of California, 2VA San Diego Healthcare System, San Diego, CA, USAAbstract: Post-herpetic neuralgia is a neuropathic pain syndrome resulting from an insult to the peripheral and central nervous systems caused by the varicella zoster virus. Spontaneous pain may result in the persistent sensation of burning, tingling, or aching and may be associated with thermally or mechanically provoked pain, resulting in hyperalgesia or allodynia. The majority of cases occur in patients over the age of 50 years. Gabapentin is a structural analog of gamma aminobutyric acid that binds to the α2-δ site of voltage-dependent calcium channels and modulates the influx of calcium, with a resulting reduction in excitatory neurotransmitter release. Gabapentin is effective in reducing neuropathic pain due to post-herpetic neuralgia when given at least three times per day, due to its short half-life, resulting in demonstrable fluctuations in plasma levels. Gabapentin has dose-limiting side effects that prevent some patients from achieving therapeutic plasma levels, such as somnolence (27.4%, dizziness (23.9%, and ataxia (7.1%. Gralise™ is a once-daily extended-release formulation of gabapentin that has been developed using AcuForm™ technology. AcuForm is a polymer-based drug delivery system that retains the tablet in the stomach and upper gastrointestinal tract for a sustained period of time. Once-daily dosing has been shown to provide comparable drug exposure with an identical daily dose of the immediate-release formulation when administered three times daily. Participants given Gralise 1800 mg daily had a statistically significant reduction in average daily pain intensity scores compared with placebo, reduced sleep interference due to pain, and a greater percent of participants reporting being much or very much improved on

  17. El Bocavirus humano: un nuevo virus respiratorio Human bocavirus: a new respiratory virus

    Directory of Open Access Journals (Sweden)

    Carlos Aguirre Muñoz

    2006-01-01

    Full Text Available Las infecciones respiratorias agudas son una causa muy importante de morbilidad y mortalidad, especialmente en los niños y en los países en desarrollo. Con los métodos de laboratorio actuales, aproximadamente una tercera parte de estas infecciones se queda sin diagnóstico etiológico. Se acepta que los virus juegan un papel cardinal y que más de 200 virus, pertenecientes a seis familias virales están implicados en la génesis de este problema. La familia Parvoviridae se conoce desde mediados del siglo XX. El Parvovirus humano B19, identificado en 1980 y causante de enfermedades febriles y exantemáticas, fue considerado por muchos años como el único miembro de esta familia capaz de afectar a la especie humana. Sin embargo, un grupo de investigadores suecos comandado por Tobías Allander informó en agosto de 2005 el hallazgo de un nuevo Parvovirus, denominado provisionalmente Bocavirus humano, relacionado con infección respiratoria aguda en niños. En este artículo se resumen las características de este nuevo agente, se resalta la importancia de su hallazgo y de la técnica de investigación empleada. Respiratory tract infections are a leading cause of morbidity and mortality, mainly in children and also in developing countries. The aethiology of approximately 30% of these infections remains obscure, using current laboratory methods. It has been accepted that viruses play an important role and more than 200 viruses, belonging to 6 viral families are implied in the pathogenesis of this problem. Parvoviridae family has been known since the middle of the XX century. Human Parvovirus B19 was identified in 1980; it causes rashes and febrile diseases and it was considered for many years as the only member of this family able to affect humans. However, Dr. Tobias Allander and colleagues, at Karolinska Institut, have discovered a previously unknown parvovirus, called Human Bocavirus, that has been found to affect children, causing lower

  18. Extracellular biosynthesis of silver nanoparticles using the cell-free filtrate of nematophagous fungus Duddingtonia flagrans

    Directory of Open Access Journals (Sweden)

    Costa Silva LP

    2017-08-01

    Full Text Available Laryssa Pinheiro Costa Silva,1 Jairo Pinto Oliveira,2 Wanderson Juvencio Keijok,2 André Romero da Silva,3 Anderson Rocha Aguiar,1 Marco Cesar Cunegundes Guimarães,2 Carolina Magri Ferraz,1 Jackson Victor Araújo,4 Fernando Luiz Tobias,5 Fábio Ribeiro Braga1 1Department of Parasitology, University Vila Velha, Vila Velha, Espírito Santo, Brazil; 2Morphology Department, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil; 3Federal Institute of Education, Science and Technology of Espírito Santo, Aracruz, Espírito Santo, Brazil; 4Department of Veterinary Medicine, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil; 5Department of Microbiology, University Vila Velha, Vila Velha, Espírito Santo, Brazil Abstract: The biosynthesis of metallic nanoparticles (NPs using biological systems such as fungi has evolved to become an important area of nanobiotechnology. Herein, we report for the first time the extracellular synthesis of highly stable silver NPs (AgNPs using the nematophagous fungus Duddingtonia flagrans (AC001. The fungal cell-free filtrate was analyzed by the Bradford method and 3,5-dinitrosalicylic acid assay and used to synthesize the AgNPs in the presence of a 1 mM AgNO3 solution. They have been characterized by UV–Vis spectroscopy, X-ray diffraction, transmission electron microscopy, dynamic light scattering, Zeta potential measurements, Fourier-transform infrared, and Raman spectroscopes. UV–Vis spectroscopy confirmed bioreduction, while X-ray diffractometry established the crystalline nature of the AgNPs. Dynamic light scattering and transmission electron microscopy images showed approximately 11, 38 nm monodisperse and quasispherical AgNPs. Zeta potential analysis was able to show a considerable stability of AgNPs. The N–H stretches in Fourier-transform infrared spectroscopy indicate the presence of protein molecules. The Raman bands suggest that chitinase was involved in the growth and

  19. Untypical Undergraduate Research: Player Motion Analysis in Sports

    Science.gov (United States)

    Loerke, Dinah

    There is significant concern about the degree of attrition in STEM disciplines from the start of K-12 through to the end of higher education, and the analysis of the `leaky pipeline' from the various institutions has identified a critical decline - which may be as high as 60 percent - between the fraction of students who identify as having an interest in a science or engineering major at the start of college/university, and the fraction of students who ultimately graduate with a STEM degree. It has been shown that this decline is even more dramatic for women and underrepresented minorities (Blickenstaff 2005, Metcalf 2010). One intervention which has been proven to be effective for retention of potential STEM students is early research experience, particularly if it facilitates the students' integration into a STEM learning community (Graham et al. 2013, Toven-Lindsey et al. 2015). In other words, to retain students in STEM majors, we would like to encourage them to `think of themselves as scientists', and simultaneously promote supportive peer networks. The University of Denver (DU) already has a strong undergraduate research program. However, while the current program provides valuable training for many students, it likely comes too late to be effective for student retention in STEM, because it primarily serves older students who have already finished the basic coursework in their discipline; within physics, we know that the introductory physics courses already serve as gatekeeper courses that cause many gifted but `non-typical' students to lose interest in pursuing a STEM major (Tobias 1990). To address this issue, my lab is developing a small research spinoff program in which we apply spatiotemporal motion analysis to the motion trajectories of players in sports, using video recordings of DU Pioneer hockey games. This project aims to fulfill a dual purpose: The research is framed in a way that we think is attractive and accessible for beginning students who

  20. Intrathecal morphine attenuates acute opioid tolerance secondary to remifentanil infusions during spinal surgery in adolescents

    Directory of Open Access Journals (Sweden)

    Tripi PA

    2015-09-01

    Full Text Available Paul A Tripi,1 Matthew E Kuestner,1 Connie S Poe-Kochert,2 Kasia Rubin,1 Jochen P Son-Hing,2 George H Thompson,2 Joseph D Tobias3 1Division of Pediatric Anesthesiology, 2Division of Pediatric Orthopaedic Surgery, Rainbow Babies and Children's Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, 3Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA Introduction: The unique pharmacokinetic properties of remifentanil with a context-sensitive half-life unaffected by length of infusion contribute to its frequent use during anesthetic management during posterior spinal fusion in children and adolescents. However, its intraoperative administration can lead to increased postoperative analgesic requirements, which is postulated to be the result of acute opioid tolerance with enhancement of spinal N-methyl-D-aspartate receptor function. Although strategies to prevent or reduce tolerance have included the coadministration of longer acting opioids or ketamine, the majority of these studies have demonstrated little to no benefit. The current study retrospectively evaluates the efficacy of intrathecal morphine (ITM in preventing hyperalgesia following a remifentanil infusion.Methods: We retrospectively analyzed 54 patients undergoing posterior spinal fusion with segmental spinal instrumentation, to evaluate the effects of ITM on hyperalgesia from remifentanil. Patients were divided into two groups based on whether they did or did not receive remifentanil during the surgery: no remifentanil (control group (n=27 and remifentanil (study group (n=27. Data included demographics, remifentanil dose and duration, Wong–Baker visual analog scale postoperative pain scores, and postoperative intravenous morphine consumption in the first 48 postoperative hours.Results: The demographics of the two study groups were similar. There were no differences in the Wong–Baker visual analog

  1. Adherence to oral anticoagulant therapy in secondary stroke prevention – impact of the novel oral anticoagulants

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    Luger S

    2015-11-01

    Full Text Available Sebastian Luger,1 Carina Hohmann,2 Daniela Niemann,1 Peter Kraft,3 Ignaz Gunreben,3 Tobias Neumann-Haefelin,2 Christoph Kleinschnitz,3 Helmuth Steinmetz,1 Christian Foerch,1 Waltraud Pfeilschifter1 1Department of Neurology, University Hospital Frankfurt, Frankfurt am Main, 2Department of Neurology, Klinikum Fulda gAG, Fulda, 3Department of Neurology, University Hospital Würzburg, Würzburg, Germany Background: Oral anticoagulant therapy (OAT potently prevents strokes in patients with atrial fibrillation. Vitamin K antagonists (VKA have been the standard of care for long-term OAT for decades, but non-VKA oral anticoagulants (NOAC have recently been approved for this indication, and raised many questions, among them their influence on medication adherence. We assessed adherence to VKA and NOAC in secondary stroke prevention. Methods: All patients treated from October 2011 to September 2012 for ischemic stroke or transient ischemic attack with a subsequent indication for OAT, at three academic hospitals were entered into a prospective registry, and baseline data and antithrombotic treatment at discharge were recorded. At the 1-year follow-up, we assessed the adherence to different OAT strategies and patients’ adherence to their respective OAT. We noted OAT changes, reasons to change treatment, and factors that influence persistence to the prescribed OAT. Results: In patients discharged on OAT, we achieved a fatality corrected response rate of 73.3% (n=209. A total of 92% of these patients received OAT at the 1-year follow-up. We observed good adherence to both VKA and NOAC (VKA, 80.9%; NOAC, 74.8%; P=0.243 with a statistically nonsignificant tendency toward a weaker adherence to dabigatran. Disability at 1-year follow-up was an independent predictor of lower adherence to any OAT after multivariate analysis, whereas the choice of OAT did not have a relevant influence. Conclusion: One-year adherence to OAT after stroke is strong (>90% and patients

  2. Questionnaire-based evaluation of everyday competence in older adults

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    Tobias Kalisch

    2011-01-01

    Full Text Available Tobias Kalisch1, Julia Richter3, Melanie Lenz1, Jan-Christoph Kattenstroth2, Izabela Kolankowska2, Martin Tegenthoff1, Hubert R Dinse21Department of Neurology, BG-Kliniken Bergmannsheil, 2Neural Plasticity Lab, Institute for Neuroinformatics, Department of Theoretical Biology, 3Faculty of Psychology, Department of Methods, Diagnostics and Evaluation, Ruhr-University Bochum, GermanyBackground: Gerontological research aims at understanding factors that are crucial for mediating “successful aging”. This term denotes the absence of significant disease and disabilities, maintenance of high levels of physical and cognitive function, and preservation of social and productive activities. Preservation of an active lifestyle is considered an effective means through which everyday competence can be attained. In this context, it is crucial to obtain ratings of modern day older adults’ everyday competence by means of appropriate assessments. Here, we introduce the Everyday Competence Questionnaire (ECQ, designed to assess healthy older adults' everyday competence.Methods: The ECQ includes 17 items, covering housekeeping, leisure activities, sports, daily routines, manual skills, subjective well-being, and general linguistic usage. The ECQ was administered to a population of 158 healthy subjects aged 60–91 years, who were divided into groups on the basis of their physical activity. These groups were community-dwelling subjects, those living independently and having a sedentary lifestyle, those living independently but characterized by a general lifestyle without any noteworthy physical activity, and those living independently and exercising regularly. Age, gender, and education levels were balanced between the groups.Results: Using the ECQ, we could identify and distinguish different everyday competence levels between the groups tested: Subjects characterized by an active lifestyle outperformed all other groups. Subjects characterized by a general

  3. Caregivers’ knowledge and acceptance of complementary and alternative medicine in a tertiary care pediatric hospital

    Directory of Open Access Journals (Sweden)

    Trifa M

    2018-03-01

    Full Text Available Mehdi Trifa,1,2 Dmitry Tumin,1,3 Hina Walia,1 Kathleen L Lemanek,4 Joseph D Tobias,1,3 Tarun Bhalla1,3 1Department of Anesthesiology and Pain Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 2Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia; 3Department of Anesthesiology and Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USA; 4Department of Pediatric Psychology and Neuropsychology, Nationwide Children’s Hospital, Columbus, OH, USA Background: The use of complementary and alternative medicine (CAM therapies has increased in children, especially in those with chronic health conditions. However, this increase may not translate into acceptance of CAM in the perioperative setting. We surveyed caregivers of patients undergoing surgery to determine their knowledge and acceptance of hypnotherapy, acupuncture, and music therapy as alternatives to standard medication in the perioperative period. Materials and methods: An anonymous, 12-question survey was administered to caregivers of children undergoing procedures under general anesthesia. Caregivers reported their knowledge about hypnotherapy, music therapy, and acupuncture and interest in one of these methods during the perioperative period. CAM acceptance was defined as interest in one or more CAM methods.Results: Data from 164 caregivers were analyzed. The majority of caregivers were 20–40 years of age (68% and mothers of the patient (82%. Caregivers were most familiar with acupuncture (70%, followed by music therapy (60% and hypnotherapy (38%. Overall CAM acceptance was 51%. The acceptance of specific CAM modalities was highest for music therapy (50%, followed by hypnotherapy (17% and acupuncture (13%. In multivariable logistic regression, familiarity with music therapy was associated with greater odds of CAM acceptance (odds ratio=3.36; 95% CI: 1.46, 7.74; P=0.004.Conclusion: Overall CAM acceptance among caregivers of children

  4. Lung vital capacity and oxygen saturation in adults with cerebral palsy

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    Lampe R

    2014-12-01

    Full Text Available Renée Lampe,1,2 Tobias Blumenstein,2 Varvara Turova,2 Ana Alves-Pinto2 1Markus Würth Stiftungsprofessur, Technical University of Munich, Munich, Germany; 2Research Unit for Cerebral Palsy and Children Neuroorthopaedics of the Buhl-Strohmaier Foundation, Orthopedic Department of the Clinic “rechts der Isar” of the Technical University of Munich, Munich, Germany Background: Individuals with infantile cerebral palsy have multiple disabilities. The most conspicuous syndrome being investigated from many aspects is motor movement disorder with a spastic gait pattern. The lung function of adults with spasticity attracts less attention in the literature. This is surprising because decreased thoracic mobility and longstanding scoliosis should have an impact on lung function. With increasing age and the level of disability, individuals become susceptible to lung infections and reflux illness, and these are accompanied by increased aspiration risk. This study examined, with different methods, to what extent adults with congenital cerebral palsy and acquired spastic paresis – following traumatic brain injury – showed restriction of lung function. It also assessed the contribution of disability level on this restriction.Methods: The oxygen saturation of 46 adults with a diagnosis of cerebral palsy was measured with an oximeter. Lung vital capacity was measured with a mobile spirometer and excursion of the thorax was clinically registered. The gross motor function levels and the presence or absence of scoliosis were determined.Results: A significantly positive correlation between lung vital capacity and chest expansion was established. Both the lung vital capacity and the thorax excursion decreased with increases in gross motor function level. Oxygen saturation remained within the normal range in all persons, in spite of reduced values of the measured lung parameters. No statistically significant dependency between lung vital capacity and oxygen

  5. Long-term structural retinal changes in patients with optic neuritis related to multiple sclerosis

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    Andersen MR

    2017-08-01

    Full Text Available Maria Rene Andersen,1 Malte Roar,2,3 Tobias Sejbaek,2,3 Zsolt Illes,2,3 Jakob Grauslund1,3 1Department of Ophthalmology, Odense University Hospital, Odense, Denmark; 2Department of Neurology, Odense University Hospital, Odense, Denmark; 3Department of Clinical Research, University of Southern Denmark, Odense, Denmark Purpose: To evaluate the long-term structural and functional outcome in patients with multiple sclerosis (MS with and without a history of optic neuritis (ON.Methods: This was a cross-sectional study of 82 patients diagnosed with MS between 2000 and 2006 from a tertiary hospital center in Denmark. Patients gave a self-reported history of ON, and functional (visual acuity and color vision and structural (spectra domain optical coherence tomography markers of vision were tested.Results: Median age and MS duration at the time of the clinical examination were 49.9 years (range 30.7–72.6 years and 13 years (range 9–15 years, respectively. ON was not associated with impairment of visual acuity or color vision. Twenty-three patients had a history of ON in at least one eye. Compared to non-affected patients, these had a lower inferior (109 vs 113 µm, P=0.04 and temporal retinal nerve fiber layer (RNFL thickness (56 vs 67 µm, P=0.01. In an age- and sex-adjusted logistic regression model, lower inferior and temporal RNFL were associated with a higher risk of ON (odds ratio [OR] 1.56 [95% confidence interval {CI} 1.01–2.41] and OR 1.74 [95% CI 1.10–2.77] per 10 µm decrement in RNFL thickness, respectively. Twenty patients had a history of ON in one eye. Compared to the non-affected eye, this eye had a lower RNFL (109 vs 115 µm, P=0.04 and a higher central retinal thickness/mean RNFL ratio (2.7 vs 2.4, P=0.04.Conclusion: Although patients with long-term MS and a previous history of ON did not have any functional loss of vision, structural neurodegeneration could be demonstrated in the affected eye. Keywords: optic neuritis

  6. Aqueous two-phase (polyethylene glycol + sodium sulfate) system for caffeine extraction: Equilibrium diagrams and partitioning study

    International Nuclear Information System (INIS)

    Araujo Sampaio, Daniela de; Mafra, Luciana Igarashi; Yamamoto, Carlos Itsuo; Forville de Andrade, Eriel; Oberson de Souza, Michèle; Mafra, Marcos Rogério; Castilhos, Fernanda de

    2016-01-01

    Highlights: • Binodal curves of PEG (400, 4000 and 6000) + Na_2SO_4 ATPS were determined. • Tie-lines were experimentally determined for aqueous (PEG 400 + Na_2SO_4) system. • Influence of caffeine on LLE of aqueous (PEG 400 + Na_2SO_4) system was investigated. • Partitioning of caffeine in aqueous (PEG 400 + Na_2SO_4) system was investigated. • Caffeine partition showed to be dependent on temperature and TLL. - Abstract: Environmental friendly methods for liquid–liquid extraction have been taken into account due to critical conditions and ecotoxicological effects potentially produced by organic solvents applied in traditional methods. Liquid–liquid extraction using aqueous two phase systems (ATPSs) presents advantages when compared to traditional liquid–liquid extraction. (Polyethylene glycol (PEG) + sodium sulfate + water) ATPS was applied to study partition of caffeine. Binodal curves for ATPSs composed of PEG of different molecular weights (400 g · mol"−"1, 4000 g · mol"−"1 and 6000 g · mol"−"1) sodium sulfate + water were determined by cloud point method at three different temperatures (293.15, 313.15 and 333.15) K. Liquid–liquid equilibrium (LLE) data (tie-lines, slope of the tie-line and tie-lines length) were obtained applying a gravimetric method proposed by Merchuck and co-workers at the same temperatures for aqueous (PEG 400 + sodium sulfate) and aqueous (PEG 400 + sodium sulfate + caffeine) systems. Reliability of the experimental tie-line (TL) data was evaluated using the equations reported by Othmer–Tobias and satisfactory linearity was obtained. Concerning to aqueous (PEG + sodium sulfate) system, the results pointed out that the higher PEG molecular weight the largest is the heterogeneous region. Moreover, temperature showed not to be relevant on binodal curves behavior, but it influenced on tie-line slopes. Partitioning of caffeine in aqueous (PEG 400 + sodium sulfate) system was investigated at different temperatures

  7. Estimation of the depth of the thoracic epidural space in children using magnetic resonance imaging

    Directory of Open Access Journals (Sweden)

    Wani TM

    2017-03-01

    Full Text Available Tariq M Wani,1,2 Mahmood Rafiq,1 Arif Nazir,1 Hatem A Azzam,1 Usama Al Zuraigi,1 Joseph D Tobias2 1Department of Anesthesia, King Fahad Medical City, Riyadh, Saudi Arabia; 2Department of Anesthesiology and Pain Medicine, Nationwide Children’s Hospital, Columbus, OH, USA Background: The estimation of the distance from the skin to the thoracic epidural space or skin to epidural depth (SED may increase the success rate and decrease the incidence of complications during placement of a thoracic epidural catheter. Magnetic resonance imaging (MRI is the most comprehensive imaging modality of the spine, allowing for the accurate determination of tissue spaces and distances. The present study uses MRI-derived measurements to measure the SED and define the ratio between the straight and inclined SEDs at two thoracic levels (T6–7 and T9–10 in children.Methods: The T2-weighed sagittal MRI images of 109 children, ranging in age from 1 month to 8 years, undergoing radiological evaluation unrelated to spine pathology were assessed. The SEDs (inclined and straight were determined, and a comparison between the SEDs at two thoracic levels (T6–7 and T9–10 was made. Univariate and multivariate linear regression models were used to assess the relationship of the inclined thoracic T6–7 and T9–10 SED measurements with age, height, and weight.Results: Body weight demonstrated a stronger association with the SED than did the age or height with R2 values of 0.6 for T6–7 and 0.5 for T9–10. The formulae describing the relationship between the weight and the inclined SED were T6–7 inclined (mm = 7 + 0.9 × kg and T9–10 inclined (mm = 7 + 0.8 × kg.Conclusion: The depth of the pediatric thoracic epidural space shows a stronger correlation with weight than with age or height. Based on the MRI data, the predictive weight-based formulas can serve as guide to clinicians for placement of thoracic epidural catheters. Keywords: thoracic epidural space

  8. Gender-specific estimates of COPD prevalence: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Ntritsos G

    2018-05-01

    Full Text Available Georgios Ntritsos,1 Jacob Franek,2 Lazaros Belbasis,1 Maria A Christou,1 Georgios Markozannes,1 Pablo Altman,3 Robert Fogel,3 Tobias Sayre,2 Evangelia E Ntzani,1 Evangelos Evangelou1,4 1Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece; 2Doctor Evidence, Client Solutions, Santa Monica, CA, USA; 3Global Medical Affairs, Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA; 4Department of Epidemiology and Biostatistics, Imperial College London, London, UK Rationale: COPD has been perceived as being a disease of older men. However, >7 million women are estimated to live with COPD in the USA alone. Despite a growing body of literature suggesting an increasing burden of COPD in women, the evidence is limited. Objectives: To assess and synthesize the available evidence among population-based epidemiologic studies and calculate the global prevalence of COPD in men and women. Materials and methods: A systematic review and meta-analysis reporting gender-specific prevalence of COPD was undertaken. Gender-specific prevalence estimates were abstracted from relevant studies. Associated patient characteristics as well as custom variables pertaining to the diagnostic method and other important epidemiologic covariates were also collected. A Bayesian random-effects meta-analysis was performed investigating gender-specific prevalence of COPD stratified by age, geography, calendar time, study setting, diagnostic method, and disease severity. Measurements and main results: Among 194 eligible studies, summary prevalence was 9.23% (95% credible interval [CrI]: 8.16%–10.36% in men and 6.16% (95% CrI: 5.41%–6.95% in women. Gender prevalences varied widely by the World Health Organization Global Burden of Disease subregions, with the highest female prevalence found in North America (8.07% vs 7.30% and in participants in urban settings (13.03% vs 8.34%. Meta

  9. Does canopy mean N concentration explain differences in light use efficiency in 14 eddy-covariance sites?

    Science.gov (United States)

    Peltoniemi, Mikko; Pulkkinen, Minna; Kolari, Pasi; Mäkelä, Annikki

    2010-05-01

    . Mean growing season VPD was the only climatic variable which correlated significantly with the largest actual LUE; none of them correlated with potential LUE. Inclusion of nitrogen in the Prelued-model structure did not improve the goodness of fit of the model. According to our results LUE correlates with mean canopy N concentration. The correlation of mean VPD with the largest actual LUE can also be explained with the model accounting for daily variation in climate, as was made with Prelued-model for the potential LUE. Further studies utilising seasonal values of canopy N are called upon. *Acknowledgements: Eero Nikinmaa, Pertti Hari, Timo Vesala, Tuomas Laurila, Fredrik Lagergren, Meelis Mölder, Anders Lindroth, Thomas Grünwald, Christian Bernhofer, Denis Loustau, Paul Berbigier, Beverly Law, Alison Dunn, Steve Wofsy, Torbjörn Johansson, Torben Christensen, Terry Callaghan, Hans Verbeeck, Remko Duursma, Leonardo Montagnani, Dario Papale, Andreas Ibrom, Ebba Dellwik, Kim Pilegaard, Kentaro Takagi, Eva van Gorsel, Heather Keith, Sonia Wharton, Matthias Falk, Kya Tha Paw U, Matt Schroeder, Jon Lloyd

  10. The Potential of Mobile Apps for Improving Asthma Self-Management: A Review of Publicly Available and Well-Adopted Asthma Apps.

    Science.gov (United States)

    Tinschert, Peter; Jakob, Robert; Barata, Filipe; Kramer, Jan-Niklas; Kowatsch, Tobias

    2017-08-02

    components; highest correlation: r 36 =.80, Pmanagement. However, many apps suffer from low quality. Therefore, app reviews should be considered as a decision support tool before deciding which app to integrate into a patient's asthma self-management. Furthermore, several research-practice gaps were identified that app developers should consider addressing in future asthma apps. ©Peter Tinschert, Robert Jakob, Filipe Barata, Jan-Niklas Kramer, Tobias Kowatsch. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 02.08.2017.

  11. Engagement Within a Mobile Phone-Based Smoking Cessation Intervention for Adolescents and its Association With Participant Characteristics and Outcomes.

    Science.gov (United States)

    Paz Castro, Raquel; Haug, Severin; Filler, Andreas; Kowatsch, Tobias; Schaub, Michael P

    2017-11-01

    over all three models, with greater reductions in daily tobacco use than nonengagement. The majority of tobacco-smoking adolescents engaged extensively with a mobile phone-based smoking cessation program. However, not only stable engagement but also decreasing engagement with a program might be an indicator of behavioral change. Measures to avoid nonengagement among adolescents appear especially necessary for older smokers with an immigrant background who do not drink excessively. In addition, future studies should not only examine the use of specific program components but also users' engagement trajectories to better understand the mechanisms behind behavioral change. ©Raquel Paz Castro, Severin Haug, Andreas Filler, Tobias Kowatsch, Michael P Schaub. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 01.11.2017.

  12. Desert Dust Outbreaks in Southern Europe: Contribution to Daily PM10 Concentrations and Short-Term Associations with Mortality and Hospital Admissions

    Science.gov (United States)

    Stafoggia, Massimo; Zauli-Sajani, Stefano; Pey, Jorge; Samoli, Evangelia; Alessandrini, Ester; Basagaña, Xavier; Cernigliaro, Achille; Chiusolo, Monica; Demaria, Moreno; Díaz, Julio; Faustini, Annunziata; Katsouyanni, Klea; Kelessis, Apostolos G.; Linares, Cristina; Marchesi, Stefano; Medina, Sylvia; Pandolfi, Paolo; Pérez, Noemí; Querol, Xavier; Randi, Giorgia; Ranzi, Andrea; Tobias, Aurelio; Forastiere, Francesco

    2015-01-01

    , Katsouyanni K, Kelessis AG, Linares C, Marchesi S, Medina S, Pandolfi P, Pérez N, Querol X, Randi G, Ranzi A, Tobias A, Forastiere F, MED-PARTICLES Study Group. 2016. Desert dust outbreaks in Southern Europe: contribution to daily PM10 concentrations and short-term associations with mortality and hospital admissions. Environ Health Perspect 124:413–419; http://dx.doi.org/10.1289/ehp.1409164 PMID:26219103

  13. Desert Dust Outbreaks in Southern Europe: Contribution to Daily PM₁₀ Concentrations and Short-Term Associations with Mortality and Hospital Admissions.

    Science.gov (United States)

    Stafoggia, Massimo; Zauli-Sajani, Stefano; Pey, Jorge; Samoli, Evangelia; Alessandrini, Ester; Basagaña, Xavier; Cernigliaro, Achille; Chiusolo, Monica; Demaria, Moreno; Díaz, Julio; Faustini, Annunziata; Katsouyanni, Klea; Kelessis, Apostolos G; Linares, Cristina; Marchesi, Stefano; Medina, Sylvia; Pandolfi, Paolo; Pérez, Noemí; Querol, Xavier; Randi, Giorgia; Ranzi, Andrea; Tobias, Aurelio; Forastiere, Francesco

    2016-04-01

    rez N, Querol X, Randi G, Ranzi A, Tobias A, Forastiere F, MED-PARTICLES Study Group. 2016. Desert dust outbreaks in Southern Europe: contribution to daily PM10 concentrations and short-term associations with mortality and hospital admissions. Environ Health Perspect 124:413-419; http://dx.doi.org/10.1289/ehp.1409164.

  14. Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function

    Directory of Open Access Journals (Sweden)

    Waschki B

    2017-03-01

    Full Text Available Benjamin Waschki,1–3 Henrik Watz,2,3 Olaf Holz,4,5 Helgo Magnussen,2,3 Beata Olejnicka,6 Tobias Welte,5,7 Klaus F Rabe,1,3 Sabina Janciauskiene5,7 1Pneumology, LungenClinic Grosshansdorf, Grosshansdorf, Germany; 2Pulmonary Research Institute at LungenClinic Grosshansdorf, Grosshansdorf, Germany; 3Airway Research Center North (ARCN, German Center for Lung Research (DZL, Grosshansdorf, Germany; 4Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany; 5Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH, German Center for Lung Research (DZL, Hannover, Germany; 6Department of Medicine, Trelleborg Hospital, Trelleborg, Sweden; 7Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany Introduction: Plasminogen activator inhibitor-1 (PAI-1, a major inhibitor of fibrinolysis, is associated with thrombosis, obesity, insulin resistance, dyslipidemia, and premature aging, which all are coexisting conditions of chronic obstructive pulmonary disease (COPD. The role of PAI-1 in COPD with respect to metabolic and cardiovascular functions is unclear. Methods: In this study, which was nested within a prospective cohort study, the serum levels of PAI-1 were cross-sectionally measured in 74 stable COPD patients (Global Initiative for Chronic Obstructive Lung Disease [GOLD] Stages I–IV and 18 controls without lung disease. In addition, triglycerides, high-density lipoprotein cholesterol, fasting plasma glucose, waist circumference, blood pressure, smoking status, high-sensitive C-reactive protein (hs-CRP, adiponectin, ankle–brachial index, N-terminal pro-B-type natriuretic peptide, and history of comorbidities were also determined. Results: The serum levels of PAI-1 were significantly higher in COPD patients than in controls, independent of a broad spectrum of possible confounders including metabolic and cardiovascular dysfunction. A multivariate regression analysis revealed

  15. Biodegradable rifampicin-releasing coating of surgical meshes for the prevention of bacterial infections

    Directory of Open Access Journals (Sweden)

    Reinbold J

    2017-09-01

    Full Text Available Jochen Reinbold,1 Teresa Hierlemann,1 Lukas Urich,1 Ann-Kristin Uhde,1 Ingrid Müller,2 Tobias Weindl,3 Ulrich Vogel,4 Christian Schlensak,1 Hans Peter Wendel,1 Stefanie Krajewski1 1Department of Thoracic and Cardiovascular Surgery, University Hospital Tübingen, Tübingen, 2Department of Pharmaceutical Engineering, Albstadt-Sigmaringen University of Applied Science, Albstadt, 3Aimecs® GmbH Medical Solutions, Pfarrkirchen, 4Institute of Pathology and Neuropathology, Tübingen, Germany Abstract: Polypropylene mesh implants are routinely used to repair abdominal wall defects or incisional hernia. However, complications associated with mesh implantation, such as mesh-related infections, can cause serious problems and may require complete surgical removal. Hence, the aim of the present study was the development of a safe and efficient coating to reduce postoperative mesh infections. Biodegradable poly(lactide-co-glycolide acid microspheres loaded with rifampicin as an antibacterial agent were prepared through single emulsion evaporation method. The particle size distribution (67.93±3.39 µm for rifampicin-loaded microspheres and 64.43±3.61 µm for unloaded microspheres was measured by laser diffraction. Furthermore, the encapsulation efficiency of rifampicin (61.5%±2.58% was detected via ultraviolet–visible (UV/Vis spectroscopy. The drug release of rifampicin-loaded microspheres was detected by UV/Vis spectroscopy over a period of 60 days. After 60 days, 92.40%±3.54% of the encapsulated rifampicin has been continuously released. The viability of BJ fibroblasts after incubation with unloaded and rifampicin-loaded microspheres was investigated using an MTT (3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide assay, which showed no adverse effects on the cells. Furthermore, the antibacterial impact of rifampicin-loaded microspheres and mesh implants, coated with the antibacterial microspheres, was investigated using an agar diffusion

  16. Access to diagnosis, treatment, and supportive services among pharmacotherapy-treated children/adolescents with ADHD in Europe: data from the Caregiver Perspective on Pediatric ADHD survey

    Directory of Open Access Journals (Sweden)

    Fridman M

    2017-03-01

    Full Text Available Moshe Fridman,1 Tobias Banaschewski,2 Vanja Sikirica,3 Javier Quintero,4 Kristina S Chen5 1AMF Consulting, Inc., Los Angeles, CA, USA; 2Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany; 3Global Health Economics Outcomes Research and Epidemiology, Shire, Wayne, PA, USA; 4Psychiatry Department, Hospital Universitario Infanta Leonor, Complutense University, Madrid, Spain; 5Global Health Economics Outcomes Research and Epidemiology, Shire, Lexington, MA, USA Background: Attention-deficit/hyperactivity disorder (ADHD is one of the most common childhood psychiatric disorders and negatively impacts caregivers’ lives. Factors including barriers to accessing care, dissatisfaction with support services, and lack of caregiver resources may contribute to this.Objectives: To report caregivers’ experiences of ADHD diagnosis, behavioral therapy (BT, and supportive care for children/adolescents with ADHD.Methods: The Caregiver Perspective on Pediatric ADHD (CAPPA survey included caregivers of children/adolescents (6–17 years from ten European countries who were currently receiving/had received ADHD pharmacotherapy in the previous 6 months. Caregivers reported experiences of obtaining an ADHD diagnosis, access to BT, availability of caregiver resources, and level of health care/school support. Pan-EU and country-specific descriptive statistics are reported; responses were compared across countries.Results: Of 3,616 caregivers, 66% were female. Mean age of children/adolescents was 11.5 years; 80% were male. Mean time from the first doctor visit to diagnosis was 10.8 (95% confidence interval 10.2, 11.3 months; 31% of caregivers reported the greatest degrees of difficulty in obtaining an ADHD diagnosis; 44% of children/adolescents did not receive BT. Forty-seven percent of caregivers reported that sufficient resources were available

  17. Atomoxetine affects transcription/translation of the NMDA receptor and the norepinephrine transporter in the rat brain – an in vivo study

    Directory of Open Access Journals (Sweden)

    Udvardi PT

    2013-12-01

    Full Text Available Patrick T Udvardi,1,2 Karl J Föhr,3 Carolin Henes,1,2 Stefan Liebau,2 Jens Dreyhaupt,4 Tobias M Boeckers,2 Andrea G Ludolph11Department of Child and Adolescent Psychiatry and Psychotherapy, 2Institute of Anatomy and Cell Biology, 3Department of Anaesthesiology, 4Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, GermanyAbstract: Attention-deficit/hyperactivity disorder (ADHD is the most frequently diagnosed neurodevelopmental disorder. The norepinephrine transporter (NET inhibitor atomoxetine, the first nonstimulant drug licensed for ADHD treatment, also acts as an N-methyl-D-aspartate receptor (NMDAR antagonist. The compound's effects on gene expression and protein levels of NET and NMDAR subunits (1, 2A, and 2B are unknown. Therefore, adolescent Sprague Dawley rats were treated with atomoxetine (3 mg/kg, intraperitoneal injection [ip] or saline (0.9%, ip for 21 consecutive days on postnatal days (PND 21–41. In humans, atomoxetine's earliest clinical therapeutic effects emerge after 2–3 weeks. Material from prefrontal cortex, striatum (STR, mesencephalon (MES, and hippocampus (HC was analyzed either directly after treatment (PND 42 or 2 months after termination of treatment (PND 101 to assess the compound's long-term effects. In rat brains analyzed immediately after treatment, protein analysis exhibited decreased levels of the NET in HC, and NMDAR subunit 2B in both STR and HC; the transcript levels were unaltered. In rat brains probed 2 months after final atomoxetine exposure, messenger RNA analysis also revealed significantly reduced levels of genes coding for NMDAR subunits in MES and STR. NMDAR protein levels were reduced in STR and HC. Furthermore, the levels of two SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins, synaptophysin and synaptosomal-associated protein 25, were also significantly altered in both treatment groups. This in vivo study detected atomoxetine's effects

  18. Long-term outcome of laparoscopic and open surgery in patients with Crohn’s disease

    Directory of Open Access Journals (Sweden)

    Hoffmann M

    2017-11-01

    Full Text Available Martin Hoffmann,1 Dina Siebrasse,1 Erik Schlöricke,2 Ralf Bouchard,1 Tobias Keck,1 Claudia Benecke1 1Department of Surgery, University Medical Center Schleswig-Holstein, Campus Lübeck, Lübeck, 2Department of Surgery, Westküstenklinikum Heide, Heide, Germany Aim: To investigate, via data analysis, the long-term outcome of patients who underwent either laparoscopic or open surgery for Crohn’s disease.Methods: A total of 113 patients who had undergone first abdominal surgery due to Crohn’s disease between January 2000 and December 2010 in a maximum care provider facility, were included in the statistical analysis. All patients provided their informed consent prior to inclusion. Data were collected from a database. Follow-up data included data from central mortality registries, general practitioners and a specialized clinic. Statistical analysis of the general patient data and the different operations and approaches were performed with the use of chi-square test, Fisher’s exact test, and the Mann–Whitney U test.Results: The median follow-up period in case of open and laparoscopic surgery was found to be 9 and 6 years, respectively. Statistically significant differences were observed for the following parameters in case of open and laparoscopic surgery, respectively: age (median=44 vs. 36 years, range=15–76 vs. 15–72 years; p=0.007, urgency of operation (23 out of 34 planned vs. 6 out of 70 planned; p<0.001, year of resection (median=2003 vs. 2006, range=2000–2010 vs. 2000–2010; p=0.001. The length of stay in hospital was significantly shorter in the laparoscopic group than that of open surgery group (8 vs. 11 days, respectively; p<0.0001. We did not control for factors such as age and comorbidities in our statistical analysis. We also did not find any differences with regard to perioperative and 90-day mortality, surgical complications, length of specimen, stoma, surgical recurrence rate (10% in both groups and number of re

  19. Tolerability of NGX-4010, a capsaicin 8% patch, in conjunction with three topical anesthetic formulations for the treatment of neuropathic pain

    Directory of Open Access Journals (Sweden)

    Webster LR

    2012-01-01

    Full Text Available Lynn R Webster1, John F Peppin2, Frederick T Murphy3,4, Jeffrey K Tobias5, Geertrui F Vanhove51Lifetree Clinical Research and Pain Clinic, Lifetree Medical Inc, Salt Lake City, UT, USA; 2Clinical Research Division, The Pain Treatment Center of the Bluegrass, Lexington, KY, USA; 3Altoona Center for Clinical Research, Duncansville, PA, USA; 4University of Pennsylvania, School of Medicine, Philadelphia, PA, USA; 5NeurogesX Inc, San Mateo, CA, USABackground: The objective of this study was to assess the safety, tolerability, and preliminary efficacy of NGX-4010, a capsaicin 8% patch, following pretreatment with three different topical anesthetics in patients with peripheral neuropathic pain.Methods: This open-label, multicenter study enrolled 117 patients with post-herpetic neuralgia, HIV-associated distal sensory polyneuropathy, or painful diabetic neuropathy. Patients received pretreatment with one of three lidocaine 4%-based topical anesthetics (L.M.X.4® [Ferndale Laboratories Inc, Ferndale, MI], Topicaine® Gel [Estela Basso, Jupiter, FL], or Betacaine Enhanced Gel 4 [Tiberius Inc, Tampa, FL] for 60 minutes followed by a single 60- or 90-minute NGX-4010 application, and were followed for 12 weeks. Tolerability and safety measures included “pain now” Numeric Pain Rating Scale (NPRS scores, dermal assessments, medication use for treatment-related pain, adverse events (AEs, clinical laboratory parameters, physical examinations, and vital signs. The primary efficacy variable was the percentage change in mean NPRS scores for “average pain for the past 24 hours” from baseline to weeks 2 through 12.Results: Treatment with NGX-4010 following pretreatment with any of the three topical anesthetics was generally safe and well tolerated. Nearly all patients completed ≥90% of the planned NGX-4010 application duration. The most common treatment-related AEs, application-site burning and application-site pain, were transient, mostly mild or moderate

  20. Development and in vitro characterization of poly(lactide-co-glycolide microspheres loaded with an antibacterial natural drug for the treatment of long-term bacterial infections

    Directory of Open Access Journals (Sweden)

    Reinbold J

    2016-09-01

    Full Text Available Jochen Reinbold,1 Teresa Hierlemann,1 Helena Hinkel,1 Ingrid Müller,2 Martin E Maier,3 Tobias Weindl,4 Christian Schlensak,1 Hans Peter Wendel,1 Stefanie Krajewski1 1Department of Thoracic, Cardiac and Vascular Surgery, University Hospital Tuebingen, Tuebingen, 2Department of Pharmaceutical Engineering, Albstadt-Sigmaringen University, Sigmaringen, 3Institute of Organic Chemistry, University Tuebingen, Tuebingen, 4Aimecs GmbH, Pfarrkirchen, Germany Abstract: Biodegradable polymers, especially poly(lactide-co-glycolide (PLGA, have good biocompatibility and toxicological properties. In combination with active ingredients, a specialized drug delivery system can be generated. The aim of the present study was to develop a drug delivery system consisting of PLGA microspheres loaded with the natural active ingredient totarol, which has several antimicrobial mechanisms. Totarol, isolated from the Podocarpus totara tree, was purified using column chromatography, and the eluate was checked for purity using thin layer chromatography. The spherically shaped microspheres with mean diameters of 147.21±3.45 µm and 131.14±3.69 µm (totarol-loaded and -unloaded microspheres, respectively were created using the single emulsion evaporation method. Furthermore, the encapsulation efficiency, in a range of 84.72%±6.68% to 92.36%±0.99%, was measured via UV/vis spectroscopy. In a 90-day in vitro drug release study, the release of totarol was investigated by UV/vis spectroscopy as well, showing a release of 53.76%. The toxicity on cells was determined using BJ fibroblasts or Human Embryonic Kidney cells and an 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide assay, which showed no influence on the cell growth. The minimal inhibitory concentration was ascertained. A totarol concentration between 64 µg/mL and 128 µg/mL was necessary to inhibit the bacterial growth over a period of 24 hours. Biofilm formation on the surface of totarol

  1. Caregiver perspective on pediatric attention-deficit/hyperactivity disorder: medication satisfaction and symptom control

    Directory of Open Access Journals (Sweden)

    Fridman M

    2017-02-01

    Full Text Available Moshe Fridman,1 Tobias Banaschewski,2 Vanja Sikirica,3 Javier Quintero,4 M Haim Erder,3 Kristina S Chen5 1AMF Consulting, Inc., Los Angeles, CA, USA; 2Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany; 3Global Health Economics Outcomes Research and Epidemiology, Shire, Wayne, PA, USA; 4Psychiatry Department, Hospital Universitario Infanta Leonor, Complutense University, Madrid, Spain; 5Global Health Economics Outcomes Research and Epidemiology, Shire, Lexington, MA, USA Abstract: The caregiver perspective on pediatric attention-deficit/hyperactivity disorder (ADHD study (CAPPA was a web-based, cross-sectional survey of caregivers of children and adolescents (6–17 years of age with ADHD and was conducted in 10 European countries. CAPPA included caregiver assessments of global medication satisfaction, global symptom control, and satisfaction with ADHD medication attributes. Overall, 2,326 caregiver responses indicated that their child or adolescent was currently receiving ADHD medication and completed the “off medication” assessment required for inclusion in the present analyses. Responses to the single-item global medication satisfaction question indicated that 88% were satisfied (moderately satisfied to very satisfied with current medication and 18% were “very satisfied” on the single-item question. Responses to the single-item global symptom control question indicated that 47% and 19% of caregivers considered their child or adolescent’s symptoms to be “controlled” or “very well controlled”, respectively. Significant variations in response to the questions of medication satisfaction and symptom control were observed between countries. The correlation between the global medication satisfaction and global symptom control questions was 0.677 (P<0.001. Global medication satisfaction was significantly

  2. Characterizing Active Ingredients of eHealth Interventions Targeting Persons With Poorly Controlled Type 2 Diabetes Mellitus Using the Behavior Change Techniques Taxonomy: Scoping Review.

    Science.gov (United States)

    Kebede, Mihiretu M; Liedtke, Tatjana P; Möllers, Tobias; Pischke, Claudia R

    2017-10-12

    explicit to avoid ambiguity. Response: Checked and avoided of a certain behavior Author: Please note that the journal discourages the use of parenthesis to denote either and/or and prefers to be explicit to avoid ambiguity. Response: Checked and avoided "and/or" and prefers to be explicit to avoid ambiguity. Response: Checked and avoided, and feedback on outcomes of behavior. Our results suggest that the majority of BCTs employed in interventions targeting persons with T2DM revolve around the promotion of self-regulatory behavior to manage the disease or to assist patients in performing health behaviors necessary to prevent further complications of the disease. Detailed reporting of the BCTs included in interventions targeting this population may facilitate the replication and further investigation of such interventions. ©Mihiretu M Kebede, Tatjana P Liedtke, Tobias Möllers, Claudia R Pischke. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 12.10.2017.

  3. Safety in the energy economy. In memoriam Peter J. Tettinger; Sicherheit in der Energiewirtschaft. In memoriam Peter J. Tettinger

    Energy Technology Data Exchange (ETDEWEB)

    Pielow, Johann-Christian (ed.)

    2007-07-01

    safety for power plants (Christian Stenneken); (q) Legal problems of the guarantee in the supply of wind energy plants (Peter Salje); (r) Is a price or quantity supply of renewable energy to be preferred from environmentally political and energetically political view? (Helmut Karl); (s) Energy efficiency as a contribution of housing sector to the securing of energy - legal obstacles with the transition for commercial heat supply (Michael Lippert); (t) The legal regime of wind energy in Spain (Masao Javier Lopez Sako); (u) Securing of nuclear facilities in the Japanese law (Yoriaki Narito); (v) The conditions for the transmission of electricity according the atomic law (Tobias Leidinger); (w) The protection of nuclear facilities against attacks of terror considering the actual legislation (Gregor Franssen, Axel Pottschmidt); (x) The intrinsically securing obligation of the paragraph 7 sect. 2 no. 5 Atomic Energy Act (Wolfgang Otten); (y) Obligation of cooperation of persons concerned by mining and the consequences of non-compliance with this (Bettina Keienburg).

  4. Non-immunogenic dextran-coated superparamagnetic iron oxide nanoparticles: a biocompatible, size-tunable contrast agent for magnetic resonance imaging

    Directory of Open Access Journals (Sweden)

    Unterweger H

    2017-07-01

    Full Text Available Harald Unterweger,1,* Christina Janko,1,* Marc Schwarz,2 László Dézsi,3 Rudolf Urbanics,4 Jasmin Matuszak,1 Erik Őrfi,3 Tamás Fülöp,3 Tobias Bäuerle,2 János Szebeni,3,4 Clément Journé,5 Aldo R Boccaccini,6 Christoph Alexiou,1 Stefan Lyer,1 Iwona Cicha1 1Cardiovascular Nanomedicine Unit, Section of Experimental Oncology und Nanomedicine (SEON, Else Kröner-Fresenius-Stiftung-Professorship, ENT Department, University Hospital Erlangen, Friedrich-Alexander-Universitaet Erlangen-Nuernberg, 2Preclinical Imaging Platform Erlangen (PIPE, Institute of Radiology, University Hospital Erlangen, Erlangen, Germany; 3Nanomedicine Research and Education Center, Semmelweis University, 4SeroScience Ltd., Budapest, Hungary; 5Inserm U1148, Fédération de Recherche en Imagerie Multimodalités (FRIM, X Bichat Hospital, Paris Diderot University, Paris, France; 6Institute of Biomaterials, Department of Materials Science and Engineering, University Erlangen-Nuremberg, Erlangen, Germany *These authors contributed equally to this work Abstract: Iron oxide-based contrast agents have been in clinical use for magnetic resonance imaging (MRI of lymph nodes, liver, intestines, and the cardiovascular system. Superparamagnetic iron oxide nanoparticles (SPIONs have high potential as a contrast agent for MRI, but no intravenous iron oxide-containing agents are currently approved for clinical imaging. The aim of our work was to analyze the hemocompatibility and immuno-safety of a new type of dextran-coated SPIONs (SPIONdex and to characterize these nanoparticles with ultra-high-field MRI. Key parameters related to nanoparticle hemocompatibility and immuno-safety were investigated in vitro and ex vivo. To address concerns associated with hypersensitivity reactions to injectable nanoparticulate agents, we analyzed complement activation-related pseudoallergy (CARPA upon intravenous administration of SPIONdex in a pig model. Furthermore, the size-tunability of SPIONdex and

  5. Post hoc analyses of the impact of previous medication on the efficacy of lisdexamfetamine dimesylate in the treatment of attention-deficit/hyperactivity disorder in a randomized, controlled trial

    Directory of Open Access Journals (Sweden)

    Coghill DR

    2014-10-01

    Full Text Available David R Coghill,1 Tobias Banaschewski,2 Michel Lecendreux,3 César Soutullo,4 Alessandro Zuddas,5 Ben Adeyi,6 Shaw Sorooshian7 1Division of Neuroscience, University of Dundee, Dundee, UK; 2Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; 3Paediatric Sleep Centre and National Reference Centre for Orphan Diseases: Narcolepsy, Idiopathic Hypersomnia and Kleine-Levin Syndrome, Robert-Debré University Hospital, Paris, France; 4Child and Adolescent Psychiatry Unit, Department of Psychiatry and Medical Psychology, University of Navarra Clinic, Pamplona, Spain; 5Department of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy; 6Shire, Wayne, PA, USA; 7Shire, Eysins, Switzerland Background: Following the approval of lisdexamfetamine dimesylate (LDX in several European countries for the treatment of attention-deficit/hyperactivity disorder (ADHD in children and adolescents with an inadequate response to methylphenidate (MPH treatment, the aim of the present analysis was to establish the response to LDX in subgroups of patients with different ADHD medication histories. Methods: This was a post hoc subgroup analysis of data from a 7-week, European, double-blind, dose-optimized, Phase III study. Patients aged 6–17 years were randomized 1:1:1 to LDX, placebo, or osmotic-release oral system methylphenidate (OROS-MPH. OROS-MPH was included as a reference arm rather than as a direct comparator. Efficacy was assessed in patients categorized according to their ADHD medication history using the ADHD Rating Scale IV and Clinical Global Impressions-Improvement (CGI-I scores. Results: The difference between active drug and placebo in least-squares mean change from baseline to endpoint in ADHD Rating Scale IV total score (95% confidence interval was similar between the overall study population (n

  6. What Older People Like to Play: Genre Preferences and Acceptance of Casual Games.

    Science.gov (United States)

    Chesham, Alvin; Wyss, Patric; Müri, René Martin; Mosimann, Urs Peter; Nef, Tobias

    2017-04-18

    characteristics, casual puzzle and simulation games were given significantly higher game-play ratings than casual action games. Similarly, participants' control ratings for casual puzzle games were significantly higher than that for casual action and simulation games. Finally, ownership was rated significantly higher for casual puzzle and strategy games than for casual action games. The findings of this study show that CVGs have characteristics that are suitable and enjoyable for older adults. In addition, genre was found to influence enjoyment and ratings of CVG characteristics, indicating that puzzle games are particularly easy to understand, learn, and play, and are enjoyable. Future studies should continue exploring the potential of CVG interventions for older adults in improving cognitive function, everyday functioning, and well-being. We see particular potential for CVGs in people suffering from cognitive impairment due to dementia or brain injury. ©Alvin Chesham, Patric Wyss, René Martin Müri, Urs Peter Mosimann, Tobias Nef. Originally published in JMIR Serious Games (http://games.jmir.org), 18.04.2017.

  7. Factors associated with caregiver burden among pharmacotherapy-treated children/adolescents with ADHD in the Caregiver Perspective on Pediatric ADHD survey in Europe

    Directory of Open Access Journals (Sweden)

    Fridman M

    2017-02-01

    Full Text Available Moshe Fridman,1 Tobias Banaschewski,2 Vanja Sikirica,3 Javier Quintero,4 M Haim Erder,3 Kristina S Chen5 1AMF Consulting, Inc., Los Angeles, CA, USA; 2Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany; 3Global Health Economics Outcomes Research and Epidemiology, Shire, Wayne, PA, USA; 4Psychiatry Department, Hospital Universitario Infanta Leonor, Complutense University, Madrid, Spain; 5Global Health Economics Outcomes Research and Epidemiology, Shire, Lexington, MA, USA Background: Burden on caregivers of children/adolescents with attention-deficit/hyperactivity disorder (ADHD is multidimensional, but incompletely understood. Objective: To analyze caregiver burden across the concepts of work, social/family life, and parental worry/stress, in relation to selected contributing factors. Methods: The online Caregiver Perspective on Pediatric ADHD survey was fielded in ten European countries. Analysis included children/adolescents (6–17 years who were receiving/had received ADHD pharmacotherapy in the previous 6 months. Caregivers recorded their child’s/adolescent’s symptoms “on”/“off” medication (ie, when the caregiver reported that the child/adolescent forgot/chose not to take medication, before the onset of medication effect, or medication worn off. Effects of ADHD severity, comorbidities, and medication adherence on each burden outcome were assessed (multiple regression models. Results: In total, 2,326 caregivers were included (children/adolescents’ mean age: 11.5 years, 80% male. Caregivers reported missed/altered work, avoiding social activity, increased parental worry/stress, and strain on family life, despite using ADHD pharmacotherapy. Child/adolescent comorbidities and ADHD severity were significantly related to all burden concepts measured; the strongest comorbidity associations were with altered

  8. Quantum Field Theory in Curved Spacetime

    Science.gov (United States)

    Reynolds, Sally C.; Gallagher, Andrew

    2012-03-01

    List of contributors; Foreword J. T. Francis Thackeray; 1. African genesis: an evolving paradigm Sally C. Reynolds; 2. Academic genealogy Peter Ungar and Phillip V. Tobias; Part I. In Search of Origins: Evolutionary Theory, New Species, and Paths into the Past: 3. Speciation in hominin evolution Colin Groves; 4. Searching for a new paradigm for hominid origins in Chad (Central Africa) Michel Brunet; 5. From hominoid arboreality to hominid bipedalism Brigitte Senut; 6. Orrorin and the African ape/hominid dichotomy Martin Pickford; 7. A brief history and results of 40 years of Sterkfontein excavations Ronald J. Clarke; Part II. Hominin Morphology Through Time: Brains, Bodies and Teeth: 8. Hominin brain evolution, 1925-2011: an emerging overview Dean Falk; 9. The issue of brain reorganisation in Australopithecus and early hominids: Dart had it right Ralph L. Holloway; 10. The mass of the human brain: is it a spandrel? Paul R. Manger, Jason Hemingway, Muhammad Spocter and Andrew Gallagher; 11. Origin and diversity of early hominin bipedalism Henry M. McHenry; 12. Forelimb adaptations in Australopithecus afarensis Michelle S. M. Drapeau; 13. Hominin proximal femur morphology from the Tugen Hills to Flores Brian G. Richmond and William L. Jungers; 14. Daily rates of dentine formation and root extension rates in Paranthropus boisei, KNM-ER 1817, from Koobi Fora, Kenya M. Christopher Dean; 15. On the evolutionary development of early hominid molar teeth and the Gondolin Paranthropus molar Kevin L. Kuykendall; 16. Digital South African fossils: morphological studies using reference-based reconstruction and electronic preparation Gerhard W. Weber, Philipp Gunz, Simon Neubauer, Philipp Mitteroecker and Fred L. Bookstein; Part III. Modern Human Origins: Patterns, and Processes: 17. Body size in African Middle Pleistocene Homo Steven E. Churchill, Lee R. Berger, Adam Hartstone-Rose and Headman Zondo; 18. The African origin of recent humanity Milford H. Wolpoff and Sang-Hee Lee

  9. Femoral nerve blockade using various concentrations of local anesthetic for knee arthroscopy in the pediatric population

    Directory of Open Access Journals (Sweden)

    Veneziano G

    2016-11-01

    Full Text Available Giorgio Veneziano,1,2 Jennifer Tripi,1 Dmitry Tumin,1 Mumin Hakim,1 David Martin,1,2 Ralph Beltran,1,2 Kevin Klingele,3,4 Tarun Bhalla,1,2 Joseph D Tobias1,2 1Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, 2Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, 3Department of Orthopedic Surgery, Nationwide Children’s Hospital, 4Department of Orthopedic Surgery, The Ohio State University College of Medicine, Columbus, OH, USA Background: Femoral nerve blockade (FNB provides effective postoperative analgesia in children undergoing arthroscopic knee surgery as evidenced by their opioid-sparing effects and decreased postoperative pain scores. Increasing the local anesthetic concentration in peripheral nerve blockade for adults undergoing orthopedic surgery has been shown to be beneficial, increasing block success rate, and providing a longer duration of analgesia. The effect of increasing the concentration of local anesthetic in extremity blocks in children remains largely unexplored.Methods: We retrospectively evaluated the effectiveness of FNB using three concentrations of local anesthetic (ropivacaine 0.2%, bupivacaine 0.25%, and ropivacaine 0.5% in children and adolescents undergoing arthroscopic knee surgery. The primary outcome evaluated was postoperative opioid consumption before discharge. Secondary outcomes included post-anesthesia care unit (PACU and hospital discharge times, first pain score in PACU, and the incidence of adverse events.Results: Two hundred and sixty-nine children and adolescents who received a FNB for arthroscopic knee surgery from January 2010 to December 2013 were included for analysis. Local anesthetic used in FNB was ropivacaine 0.2% in 116 (43% cases, ropivacaine 0.5% in 75 (28% cases, and bupivacaine 0.25% in 78 (29% cases. Median postoperative opioid consumption (mg/kg intravenous morphine equivalents in the ropivacaine 0.5% group was 0

  10. A Mobile Phone-Based Life Skills Training Program for Substance Use Prevention Among Adolescents: Pre-Post Study on the Acceptance and Potential Effectiveness of the Program, Ready4life.

    Science.gov (United States)

    Haug, Severin; Paz Castro, Raquel; Meyer, Christian; Filler, Andreas; Kowatsch, Tobias; Schaub, Michael P

    2017-10-04

    . The mean number of interactive program activities that participants engaged in was 15.5 (SD 13.3) out of a total of 39 possible activities. Follow-up assessments were completed by 436 of the 877 (49.7%) participants. GEE analyses revealed decreased perceived stress (odds ratio, OR=0.93; 95% CI 0.87-0.99; P=.03) and increases in several life skills addressed between baseline and the follow-up assessment. The proportion of adolescents with at-risk alcohol use declined from 20.2% at baseline to 15.5% at follow-up (OR 0.70, 95% CI 0.53-0.93; P=.01), whereas no significant changes were obtained for tobacco (OR 0.94, 95% CI 0.65-1.36; P=.76) or cannabis use (OR 0.91, 95% CI 0.67-1.24; P=.54). These results reveal high-level acceptance and promising effectiveness of this interventional approach, which could be easily and economically implemented. A reasonable next step would be to test the efficacy of this program within a controlled trial. ©Severin Haug, Raquel Paz Castro, Christian Meyer, Andreas Filler, Tobias Kowatsch, Michael P Schaub. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 04.10.2017.

  11. Research for energy optimized building. Status seminar; Forschung fuer Energieoptimiertes Bauen. Statusseminar

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    ); (17) Quality assurance for geothermal probes for heating and cooling (Manfred Reuss, Markus Proell, Roland Koenigsdorff); (18) Phase change fluids for heat storage in the air conditioning of buildings (Stefan Gschwander, Peter Schossig); (19) Thermochemical storages for heating, air conditioning and dehumidification (Andreas Hauer); (20) A survey of solar storage applications (Klaus Vajen et al.); (21) Application of phase change materials (PCM) in the construction of wooden buildings in order to avoid an overheating in summer (Christoph Kempkes, Stephan Schlitzberger); (22) The air cross-flowed boulders storage - Innovation in the aeration of buildings (Mario Reichel, Ronny Stieber); (23) GeoTU6 - Utilization of geotheremal energy in tunnels in the areas of cities using the tram system tunnel Stuttgart-Fasanenhof (U69) as an example (Marcus Schneider et al.); (24) A simulation-based automation and optimization of operation (Ursula Eicker et al.); (25) Model-based operation analysis of buildings - Methods for the recognition of mistakes and optimization in the facility management (Christian Neumann, Dirk Jacob); (26) Optimization of operation of university buildings (Werner Jensch et al.); (27) EnBop - Energetic optimization of operation (Stefan Plesser, M. Norbert Fisch); (27) Monitoring at DVZ Barnim in Eberswalde (Tobias Haeusler); (28) Joint project: An energy optimized illumination at simultaneous improvement of the life quality using daylight and new lamp technology and series technology (Heinrich Kaase et al.).

  12. Epic Allies, a Gamified Mobile Phone App to Improve Engagement in Care, Antiretroviral Uptake, and Adherence Among Young Men Who Have Sex With Men and Young Transgender Women Who Have Sex With Men: Protocol for a Randomized Controlled Trial.

    Science.gov (United States)

    LeGrand, Sara; Muessig, Kathryn E; Platt, Alyssa; Soni, Karina; Egger, Joseph R; Nwoko, Nkechinyere; McNulty, Tobias; Hightow-Weidman, Lisa B

    2018-04-05

    primary outcome measure is viral suppression. Secondary outcome measures include engagement in care, ART uptake, ART adherence, and psychosocial barriers to engagement in care and ART adherence, including psychological distress, stigma, and social support. Baseline enrollment began in September 2015 and was completed in September 2016 (n=146), and assessment of intervention outcomes continued through August 2017. Results for primary and secondary outcome measures are expected to be reported in ClinicalTrials.gov by April 30, 2018. If successful, Epic Allies will represent a novel adherence intervention for a group disproportionately impacted by HIV in the United States. Adherent patients would require less frequent clinic visits and experience fewer HIV-related secondary infections, thereby reducing health care costs and HIV transmission. Epic Allies could easily be expanded and adopted for use among larger populations of YMSM and YTWSM, other HIV-positive populations, and for those diagnosed with other chronic diseases such as diabetes and hypertension. ClinicalTrials.gov NCT02782130; https://clinicaltrials.gov/ct2/show/NCT02782130 (Archived by Webcite at http://www.webcitation.org/6yGODyerk). ©Sara LeGrand, Kathryn E Muessig, Alyssa Platt, Karina Soni, Joseph R Egger, Nkechinyere Nwoko, Tobias McNulty, Lisa B Hightow-Weidman. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 05.04.2018.

  13. 3D Visualization Tools to Support Soil Management In Relation to Sustainable Agriculture and Ecosystem Services

    Science.gov (United States)

    Wang, Chen

    2017-04-01

    game engines as tools for supporting archaeology and the reconstruction of cultural heritage - the case-study of the Roman villa of Casal de Freiria, Journal of Archaeological Science, 38(12): 3296-3308. Wang, C., Miller, D.R., Brown I., Jiang Y., Castellazzi M, "Visualisation Techniques to Support Public Interpretation of Future Climate Change and Land Use Choices: A Case Study from N-E Scotland", International Journal of Digital Earth, Volume 9, Issue 6, pp.586-605, 2016. VLT, http://www.hutton.ac.uk/learning/exhibits/vlt Scotland's soil, http://www.soils-scotland.gov.uk/ Wang, C., Miller, D.R., Jiang Y., Donaldson-Selby, "Use of 3D Visualisation Tools for Representing Urban Greenspace Spatial Planning", 2015 IEEE International Conference on Information Science and Control Engineering Shanghai, China, April 24-26, 2015. Tobias, S., Buser, T., Buchecker, M. (2016) Does real-time visualization support local stakeholders in developing landscape visions? Environment and Planning B:Planning and Design, 43: 84¨ C197. Li.Y, Zhu. A-Xing, Shi. Z, Liu. J and Du. F, "Supplemental sampling for digital soil mapping based on prediction uncertainty from both the feature domain and the spatial domain", The Global Journal of Soil Science, Volume 284, pp 73-84, 2016. Warren-Kretzschmar. B and Haaren, C, "Communicating spatial planning decisions at the landscape and farm level with landscape visualization", Journal of Biogeosciences and Forestry, volume 7, pp 434-442, 2014.

  14. VizieR Online Data Catalog: New standards in 18th century astrometry (Lequeux, 2014)

    Science.gov (United States)

    Lequeux, J.

    2014-05-01

    named lacaillefund.dat. La Caille's complete survey of the southern sky (lacaisur.dat): During his stay in Cape Town in 1751-1752, La Caille made the first systematic survey of the sky ever, in the modern sense. 244 stars over 9766. La Caille's catalogue of zodiacal stars (lacaizod.dat): When La Caille returned from his southern expedition in 1754, he undertook the construction of a catalogue of zodiacal stars. Mayer's zodiacal catalogue (mayer.dat): At exactly the same time as La Caille, Tobias Mayer (1723-1762) in Gottingen undertook a similar catalogue of zodiacal stars, using a 6-feet radius mural quadrant made by John Bird (1709-1776). 200 stars over 998. Bradley's stellar catalogue (bradley.dat): James Bradley (1693-1762) is famous for his discovery of aberration and nutation. From 1750 to his death in 1762, he built a large stellar catalogue, from observations first with an old mural sector and after 1753 with the Bird 8-ft mural sector located in Greenwich, where it 215 stars over 3220. Piazzi's stellar catalogue (piazzi.dat): Giuseppe Piazzi (1746-1846) built a large catalogue containing 7646 stars from 1792 to 1813, observed in Palermo with an altazimuthal circle of Jesse Ramsden (1735-1800) can still be seen. 202 stars over 7646. Lalande's stellar catalogue (lalande.dat): L'Histoire celeste francaise de Lalande (Lalande 1801), which contains the unreduced observations of approximately 40,000 stars, is the first very large stellar catalogue. 198 stars over ~45000. (10 data files).

  15. Biogas in the agriculture. State of the art. Proceedings; Biogas in der Landwirtschaft. Stand und Perspektiven. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    fermentation of renewable raw materials effect organic soil carbon? (Peter Dominik et al.); (20) Efficiency of composting of residues of fermentation (Helmut Doehler et al.); (21) Feeding biogas in the natural gas grid: actual market developments in the area of gas processing and line feeding (Wolfgang Urban); (22) Practical experiences in the substitution of natural gas by bio methane in Germany (Michael Beil); (23) Biogas plants - the technical view of the network access (Uwe Klaus, Andreas Schrader); (24) Optimized cultivation of energy plants for biogas plants (Christoph Strauss); (25) Deintegration procedure - Expenditure and utility for the generation of biogas (Bjoern Schwarz et al.); (26) Biogas substrate - Which exotics have the potential for the future? (Armin Vetter); (27) The step of hydrolyse in the fermentation of renewable raw materials - Does it enhance the efficiency? (Hans Oechsner et al.); (28) Quality silage for the production of biogas (Christiane Herrmann et al.); (29) Possibilities of the optimization of mixtures of raw materials (Thomas Amon); (30) Ignition jet cogeneration plant - State of the art and perspectives using the effective post power generation of waste gas (Wolfram Dreier, Kai Liesendahl); (31) Gas-fuelled spark ignition engine - state of the art and perspectives (Thomas Elsenbruch); (32) Power generation from biogas in a fuel cell (Peter Landgraf); (33) Micro gas turbine - state of the art (Tobias Panne, Axel Widenhorn); (34) Possibilities of the reduction of the energy demand of biogas plants (Andreas Lehner, Matthias Effenberger); (35) EEG conform utilization of waste heat of agricultural biogas plants (Wolfgang Schulz). Beside these lectures twenty six poster contributions were exhibited.

  16. EDITORIAL: The next photonic revolution The next photonic revolution

    Science.gov (United States)

    Zheludev, Nikolay I.

    2009-11-01

    dependence upon active and switchable photonic metamaterials and nanophotonic devices. This revolution will lead to dramatic new science and applications on a global scale in all technologies using light, from data storage to optical processing of information, from sensing to light harvesting and energy conversion. Five plenary talks at the conference outlined its topical boundaries. They were given by Sir Michael Berry, Bristol University, UK, who spoke on the new topic of optical super-oscillations; Harry A Atwater, California Institute of Technology, USA, who gave an overview of recent developments in plasmonics; Christian Colliex, Université Paris-Sud, France, who presented the concept of electron energy-loss spectroscopy for the study of localized plasmons; Xiang Zhang, University of California at Berkeley, USA, who talked about recent achievements in the optical super-lens, and Antoinette Taylor, National Laboratory, Los Alamos, USA, who discussed recent work on tunable terahertz metamaterials. In the specially assigned `breakthrough' talks Steven Anlage, University of Maryland, USA, introduced the emerging field of superconducting meta-materials, Tobias Kippenberg, Max-Planck-Institut, Garching, Germany, talked about cavity optomechanics on a chip, while Misha Lukin, Harvard University, USA, explored the field of quantum plasmonics and Victor Prinz, Russian Academy of Science, Russia, introduced a novel class of metamaterials based on three-dimensional semiconductor nanostructures. The topical scope of this special section, to a great extent, echoes the paradigm shift in the NANOMETA community and includes papers on nanofabrication of plasmonic structure, transformation optics and invisibility, mapping of fields in nanostructures, nonlinear and magnetoplasmonic media, coherent effects in metamaterials, loss compensation in nanostructures, slow light and ultrafast switching of plasmon signals, and many other topics. The Guest Editor of this special section and the co

  17. PREFACE: Structure and dynamics determined by neutron and x-ray scattering Structure and dynamics determined by neutron and x-ray scattering

    Science.gov (United States)

    Müller-Buschbaum, Peter

    2011-06-01

    structure of pyroxene-type MnGeO3 G J Redhammer, A Senyshyn, G Tippelt and G Roth Nanostructured diblock copolymer films with embedded magnetic nanoparticles Xin Xia, Ezzeldin Metwalli, Matthias A Ruderer, Volker Körstgens, Peter Busch, Peter Böni and Peter Müller-Buschbaum Thermal expansion of a La-based bulk metallic glass: insight from in situ high-energy x-ray diffraction J Bednarcik, S Michalik, M Sikorski, C Curfs, X D Wang, J Z Jiang and H Franz The slow short-time motions of phospholipid molecules with a focus on the influence of multiple scattering and fitting artefacts Sebastian Busch and Tobias Unruh Quasi-elastic scattering under short-range order: the linear regime and beyond Michael Leitner and Gero Vogl Structural relaxation as seen by quasielastic neutron scattering on viscous Zr-Ti-Cu-Ni-Be droplets F Yang, T Kordel, D Holland-Moritz, T Unruh and A Meyer In situ observation of cluster formation during nanoparticle solution casting on a colloidal film S V Roth, G Herzog, V Körstgens, A Buffet, M Schwartzkopf, J Perlich, M M Abul Kashem, R Döhrmann, R Gehrke, A Rothkirch, K Stassig, W Wurth, G Benecke, C Li, P Fratzl, M Rawolle and P Müller-Buschbaum Inelastic neutron and x-ray scattering from incommensurate magnetic systems Peter Böni, Bertrand Roessli and Klaudia Hradil Development of magnetic moments in Fe1-xNix-alloys Benjamin Glaubitz, Stefan Buschhorn, Frank Brüssing, Radu Abrudan and Hartmut Zabel Modified mode-coupling theory for the collective dynamics of simple liquids B Schmid and W Schirmacher Inelastic neutron and low-frequency Raman scattering in niobium-phosphate glasses: the role of spatially fluctuating elastic and elasto-optic constants A Schulte, W Schirmacher, B Schmid and T Unruh The effect of heat treatment on the internal structure of nanostructured block copolymer films A Sepe, E T Hoppe, S Jaksch, D Magerl, Q Zhong, J Perlich, D Posselt, D-M Smilgies and C M Papadakis Hydrogen release from sodium alanate observed by time

  18. Overview of Light-Ion Beam Therapy

    International Nuclear Information System (INIS)

    Chu, William T.

    2006-01-01

    compared to those in conventional (photon) treatments. Wilson wrote his personal account of this pioneering work in 1997. In 1954 Cornelius Tobias and John Lawrence at the Radiation Laboratory (former E.O. Lawrence Berkeley National Laboratory) of the University of California, Berkeley performed the first therapeutic exposure of human patients to hadron (deuteron and helium ion) beams at the 184-Inch Synchrocyclotron. By 1984, or 30 years after the first proton treatment at Berkeley, programs of proton radiation treatments had opened at: University of Uppsala, Sweden, 1957; the Massachusetts General Hospital-Harvard Cyclotron Laboratory (MGH/HCL), USA, 1961; Dubna (1967), Moscow (1969) and St Petersburg (1975) in Russia; Chiba (1979) and Tsukuba (1983) in Japan; and Villigen, Switzerland, 1984. These centers used the accelerators originally constructed for nuclear physics research. The experience at these centers has confirmed the efficacy of protons and light ions in increasing the tumor dose relative to normal tissue dose, with significant improvements in local control and patient survival for several tumor sites. M.R. Raju reviewed the early clinical studies. In 1990, the Loma Linda University Medical Center in California heralded in the age of dedicated medical accelerators when it commissioned its proton therapy facility with a 250-MeV synchrotron. Since then there has been a relatively rapid increase in the number of hospital-based proton treatment centers around the world, and by 2006 there are more than a dozen commercially-built facilities in use, five new facilities under construction, and more in planning stages. In the 1950s larger synchrotrons were built in the GeV region at Brookhaven (3-GeV Cosmotron) and at Berkeley (6-GeV Bevatron), and today most of the world's largest accelerators are synchrotrons. With advances in accelerator design in the early 1970s, synchrotrons at Berkeley and Princeton accelerated ions with atomic numbers between 6 and 18, at

  19. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2004-07-01

    , and modernity in Dominican history. Stanford CA: Stanford University Press, 2003. x + 384 pp. -Eric Paul Roorda, Bernardo Vega, Almoina, Galíndez y otros crímenes de Trujillo en el extranjero. Santo Domingo: Fundación Cultural Dominicana, 2001. 147 pp.''Diario de una misión en Washington. Santo Domingo: Fundación Cultural Dominicana, 2002. 526 pp. -Gerben Nooteboom, Aspha Bijnaar, Kasmoni: Een spaartraditie in Suriname en Nederland. Amsterdam: Uitgeverij Bert Bakker, 2002. 378 pp. -Dirk H.A. Kolff, Chan E.S. Choenni ,Hindostanen: Van Brits-Indische emigranten via Suriname tot burgers van Nederland. The Hague: Communicatiebureau Sampreshan, 2003. 224 pp., Kanta Sh. Adhin (eds -Dirk H.A. Kolff, Sandew Hira, Het dagboek van Munshi Rahman Khan. The Hague: Amrit/Paramaribo: NSHI, 2003. x + 370 pp. -William H. Fisher, Neil L. Whitehead, Dark Shamans: Kanaimà and the poetics of violent death. Durham NC: Duke University Press, 2002. 309 pp. -David Scott, A.J. Simoes da Silva, The luxury of nationalist despair: George Lamming's fiction as decolonizing project. Amsterdam: Rodopi, 2000. 217 pp. -Lyn Innes, Maria Cristina Fumagalli, The flight of the vernacular. Amsterdam: Rodopi, 2001. xvi + 303 pp. -Maria Cristina Fumagalli, Tobias Döring, Caribbean-English passages: Intertextuality in a postcolonial tradition. London: Routledge, 2002. xii + 236 pp. -A. James Arnold, Celia Britton, Race and the unconscious: Freudianism in French Caribbean thought. Oxford: Legenda, 2002. 115 pp. -Nicole Roberts, Dorothy E. Mosby, Place, language, and identity in Afro-Costa Rican literature. Columbia: University of Missouri Press, 2003. xiii + 248 pp. -Stephen Steumpfle, Philip W. Scher, Carnival and the formation of a Caribbean transnation. Gainesville: University Press of Florida, 2003. xvi + 215 pp. -Peter Manuel, Frances R. Aparicho ,Musical migrations: transnationalism and cultural hybridity in Latin/o America, Volume 1. With Maria Elena Cepeda. New York: Palgrave Macmillan, 2003. 216

  20. Review of Apanteles sensu stricto (Hymenoptera, Braconidae, Microgastrinae from Area de Conservación Guanacaste, northwestern Costa Rica, with keys to all described species from Mesoamerica

    Directory of Open Access Journals (Sweden)

    Jose Fernandez-Triana

    2014-02-01

    , Elachistidae and Crambidae (Lepidoptera. About 90% of the wasp species with known host records seem to be monophagous or oligophagous at some level, parasitizing just one host family and commonly, just one species of caterpillar. Only 15 species (9% parasitize species in more than one family, and some of these cases are likely to be found to be species complexes. We have used several information sources and techniques (traditional taxonomy, molecular, software-based, biology, and geography to accelerate the process of finding and describing these new species in a hyperdiverse group such as Apanteles.The following new taxonomic and nomenclatural acts are proposed. Four species previously considered to be Apanteles are transferred to other microgastrine genera: Dolichogenidea hedyleptae (Muesebeck, 1958 comb. n., Dolichogenidea politiventris (Muesebeck, 1958 comb. n., Rhygoplitis sanctivincenti (Ashmead, 1900 comb. n., and Illidops scutellaris (Muesebeck, 1921 comb. rev. One European species that is a secondary homonym to a Mesoamerican species is removed from Apanteles and transferred to another genus: Iconella albinervis (Tobias, 1964 stat. rev. The name Apanteles albinervican Shenefelt, 1972, is an invalid replacement name for Apanteles albinervis (Cameron, 1904 stat. rev., and thus the later name is reinstated as valid. The following 186 species, all in Apanteles and all authored by Fernández-Triana, are described as species nova: adelinamoralesae, adrianachavarriae, adrianaguilarae, adrianguadamuzi, aichagirardae, aidalopezae, albanjimenezi, alejandromasisi, alejandromorai, minorcarmonai, alvarougaldei, federicomatarritai, anabellecordobae, rostermoragai, anamarencoae, anamartinesae, anapiedrae, anariasae, andreacalvoae, angelsolisi, arielopezi, bernardoespinozai, bernyapui, bettymarchenae, bienvenidachavarriae, calixtomoragai, carloscastilloi, carlosguadamuzi, eliethcantillanoae, carlosrodriguezi, carlosviquezi, carloszunigai, carolinacanoae, christianzunigai

  1. Overview of Light-Ion Beam Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Chu, William T.

    2006-03-16

    treatment volume compared to those in conventional (photon) treatments. Wilson wrote his personal account of this pioneering work in 1997. In 1954 Cornelius Tobias and John Lawrence at the Radiation Laboratory (former E.O. Lawrence Berkeley National Laboratory) of the University of California, Berkeley performed the first therapeutic exposure of human patients to hadron (deuteron and helium ion) beams at the 184-Inch Synchrocyclotron. By 1984, or 30 years after the first proton treatment at Berkeley, programs of proton radiation treatments had opened at: University of Uppsala, Sweden, 1957; the Massachusetts General Hospital-Harvard Cyclotron Laboratory (MGH/HCL), USA, 1961; Dubna (1967), Moscow (1969) and St Petersburg (1975) in Russia; Chiba (1979) and Tsukuba (1983) in Japan; and Villigen, Switzerland, 1984. These centers used the accelerators originally constructed for nuclear physics research. The experience at these centers has confirmed the efficacy of protons and light ions in increasing the tumor dose relative to normal tissue dose, with significant improvements in local control and patient survival for several tumor sites. M.R. Raju reviewed the early clinical studies. In 1990, the Loma Linda University Medical Center in California heralded in the age of dedicated medical accelerators when it commissioned its proton therapy facility with a 250-MeV synchrotron. Since then there has been a relatively rapid increase in the number of hospital-based proton treatment centers around the world, and by 2006 there are more than a dozen commercially-built facilities in use, five new facilities under construction, and more in planning stages. In the 1950s larger synchrotrons were built in the GeV region at Brookhaven (3-GeV Cosmotron) and at Berkeley (6-GeV Bevatron), and today most of the world's largest accelerators are synchrotrons. With advances in accelerator design in the early 1970s, synchrotrons at Berkeley and Princeton accelerated ions with atomic numbers

  2. EDITORIAL: Focus on Quantum Information and Many-Body Theory

    Science.gov (United States)

    Eisert, Jens; Plenio, Martin B.

    2010-02-01

    and F Verstraete SIMULATION AND DYNAMICS A quantum differentiation of k-SAT instances B Tamir and G Ortiz Classical Ising model test for quantum circuits Joseph Geraci and Daniel A Lidar Exact matrix product solutions in the Heisenberg picture of an open quantum spin chain S R Clark, J Prior, M J Hartmann, D Jaksch and M B Plenio Exact solution of Markovian master equations for quadratic Fermi systems: thermal baths, open XY spin chains and non-equilibrium phase transition Tomaž Prosen and Bojan Žunkovič Quantum kinetic Ising models R Augusiak, F M Cucchietti, F Haake and M Lewenstein ENTANGLEMENT AND SPECTRAL PROPERTIES Ground states of unfrustrated spin Hamiltonians satisfy an area law Niel de Beaudrap, Tobias J Osborne and Jens Eisert Correlation density matrices for one-dimensional quantum chains based on the density matrix renormalization group W Münder, A Weichselbaum, A Holzner, Jan von Delft and C L Henley The invariant-comb approach and its relation to the balancedness of multipartite entangled states Andreas Osterloh and Jens Siewert Entanglement scaling of fractional quantum Hall states through geometric deformations Andreas M Läuchli, Emil J Bergholtz and Masudul Haque Entanglement versus gap for one-dimensional spin systems Daniel Gottesman and M B Hastings Entanglement spectra of critical and near-critical systems in one dimension F Pollmann and J E Moore Macroscopic bound entanglement in thermal graph states D Cavalcanti, L Aolita, A Ferraro, A García-Saez and A Acín Entanglement at the quantum phase transition in a harmonic lattice Elisabeth Rieper, Janet Anders and Vlatko Vedral Multipartite entanglement and frustration P Facchi, G Florio, U Marzolino, G Parisi and S Pascazio Entropic uncertainty relations—a survey Stephanie Wehner and Andreas Winter Entanglement in a spin system with inverse square statistical interaction D Giuliano, A Sindona, G Falcone, F Plastina and L Amico APPLICATIONS Time-dependent currents of one-dimensional bosons

  3. EMRS Spring Meeting 2014 Symposium D: Phonons and fluctuations in low dimensional structures

    International Nuclear Information System (INIS)

    2014-01-01

    on 8th and 9th September 2011, attended by 55 researchers and (4) the 3rd Workshop on Phonons and Fluctuations, held in Saint Feliux de Guixols (Girona, Spain) during 21 to 24th May 2012 attended by 65 participants from Europe and the USA. These papers in this proceeding are examples of the work presented at the symposium. They represent the tip of the iceberg, as the symposium attracted over 100 abstracts. The meeting room was usually full with an audience varying between 40 and 100 participants. The plenary presentation was given by Prof. Gang Chen (MIT) on ''Ballistic and Coherent Phonon Heat Conduction in Bulk Materials and Nanostructures'', which was warmly welcome by an eager and highly motivated audience. The invited speakers were: Prof. Thomas Dehoux (U. Bordeaux), Dr S. Chung (U. New South Wales, Australia), Prof. A. Goni (CSIC-ICMAB), Prof. Giuliano Benenti (U. Insubria), Dr. Davide Donadio (Max Planck Institute for Polymer Research, Mainz), Prof. George Fytas (University of Crete), Prof. Dr. Tobias Kippenberg (EPFL, Switzerland), Prof. Bernard Perrin (INSP, Paris), Prof. Gyaneshwar P. Srivastava, U. Exeter) and Prof. Dr. Achim Kittel (U. Oldenburg). The organisers are very grateful to them for supporting the symposium and sharing their latest research results with the symposium participants. The symposium organisers recognised the participation of students and awarded prizes to the two Best Student Presentations, which went to Valeria Lacatena (IEMN, Lille) with an invited presentation entitled ''Efficient reduction of thermal conductivity in silicon using phononic-engineered membranes'' and to Yan Qing Liu (Institute Neel, Grenoble) who presented the talk entitled ''Sensitive 3-omega measurements of epitaxial thermoelectric thin films''. The poster session had about fifty posters and the four best poster prizes went to: Konstanze Hahn et al. (U. Cagliari) poster title ''Determination of

  4. Jornais de internet simulam o papel

    Directory of Open Access Journals (Sweden)

    Luciana Moherdaui

    2015-09-01

    news. Journal of Peace Research, vol. 1. Noruega, 1965. p. 64-90. Disponível em http://bit.ly/Ak9NGw. Acesso jul. 2015. GANS, H. Deciding what´s news. A study of CBS Evening News, NBC Nightly News, News, Newsweek and Time. New York: Pantheon Books, 1979. GIBSON, W. Neuromancer. São Paulo: Editora Aleph, 2003. JOHNSON, S. Cultura da interface: como o computador transforma nossa maneira de criar e comunicar. Rio de Janeiro: Jorge Zahar, 2001. KUNCZIK, M. Conceitos de jornalismo. São Paulo: Edusp, 1997. LÉVY, P. Cibercultura. São Paulo: Editora 34, 1999. LIPPMAN, W. Opinião pública. Petrópolis: Vozes, 2008. MANOVICH, L. Software takes command. Software Studies, EUA, 20 nov. 2008 In: http://bit.ly/1TPMWID Acesso jul. 2015. MOHERDAUI, L. Guia de estilo web: produção e edição de notícias on-line. 3ª ed. São Paulo: Senac, 2007. MONACHESI, J. Contra a clicagem burra. Folha de S. Paulo, São Paulo, jan. 2004, p. 8 - 9 - 18. NELSON, T. Deeper Cosmology, Deeper Documents, 2001. The Twelfth ACM Conference on Hypertext and Hypermedia, Dinamarca, 14-18 ago. 2001 http://bit.ly/xpgIMR. Acesso jul. 2015. PAUL, N. The elements of digital story making. Universidade de Minsesota, EUA, 2005. ____________. New News retrospective: Is online news reaching its potential? Online Journalism Review, Califórnia, 24 mar. 2005. Disponível em http://bit.ly/1Iec9E5. Acesso jul. 2015. SCHUDSON, M. The Sociology of News. New York: Jeffrey C. Alexander, 2003. SHIRKY, C. A cultura da participação. Rio de Janeiro: Zahar, 2010. SOUSA, J. P. Tobias Peucer. Progenitor da Teoria do Jornalismo. Biblioteca On-Line de Ciências da Comunicação. Portugal, 2004. Disponível em: http://bit.ly/y5USBi. Acesso jul. 2015. TIM Berners-Lee on the next web. TED 2009, EUA. Disponível em http://bit.ly/1cwDl7M. Acesso 24 ago. 2015. TUCHMAN, G. Making news: a study in the construction of reality. New York: Press. 1978. TWITTER noticiou morte de Bin Laden antes de Obama. Infoexame, São Paulo, 2 mai. 2011

  5. EMRS Spring Meeting 2014 Symposium D: Phonons and fluctuations in low dimensional structures

    Science.gov (United States)

    2014-11-01

    September 2011, attended by 55 researchers and (4) the 3rd Workshop on Phonons & Fluctuations, held in Saint Feliux de Guixols (Girona, Spain) during 21 to 24th May 2012 attended by 65 participants from Europe and the USA. These papers in this proceeding are examples of the work presented at the symposium. They represent the tip of the iceberg, as the symposium attracted over 100 abstracts. The meeting room was usually full with an audience varying between 40 and 100 participants. The plenary presentation was given by Prof. Gang Chen (MIT) on ''Ballistic and Coherent Phonon Heat Conduction in Bulk Materials and Nanostructures'', which was warmly welcome by an eager and highly motivated audience. The invited speakers were: Prof. Thomas Dehoux (U. Bordeaux), Dr S. Chung (U. New South Wales, Australia), Prof. A. Goni (CSIC-ICMAB), Prof. Giuliano Benenti (U. Insubria), Dr. Davide Donadio (Max Planck Institute for Polymer Research, Mainz), Prof. George Fytas (University of Crete), Prof. Dr. Tobias Kippenberg (EPFL, Switzerland), Prof. Bernard Perrin (INSP, Paris), Prof. Gyaneshwar P. Srivastava, U. Exeter) and Prof. Dr. Achim Kittel (U. Oldenburg). The organisers are very grateful to them for supporting the symposium and sharing their latest research results with the symposium participants. The symposium organisers recognised the participation of students and awarded prizes to the two Best Student Presentations, which went to Valeria Lacatena (IEMN, Lille) with an invited presentation entitled ''Efficient reduction of thermal conductivity in silicon using phononic-engineered membranes'' and to Yan Qing Liu (Institute Neel, Grenoble) who presented the talk entitled ''Sensitive 3-omega measurements of epitaxial thermoelectric thin films''. The poster session had about fifty posters and the four best poster prizes went to: Konstanze Hahn et al. (U. Cagliari) poster title ''Determination of Thermal conductivity in (nanostructured) SiGe materials'', Florian Doehring et al. (U

  6. EDITORIAL: Focus on Quantum Cryptography: Theory and Practice FOCUS ON QUANTUM CRYPTOGRAPHY: THEORY AND PRACTICE

    Science.gov (United States)

    Lütkenhaus, N.; Shields, A. J.

    2009-04-01

    distribution network in Vienna M Peev, C Pacher, R Alléaume, C Barreiro, J Bouda, W Boxleitner, T Debuisschert, E Diamanti, M Dianati, J F Dynes, S Fasel, S Fossier, M Fürst, J-D Gautier, O Gay, N Gisin, P Grangier, A Happe, Y Hasani, M Hentschel, H Hübel, G Humer, T Länger, M Legré, R Lieger, J Lodewyck, T Lorünser, N Lütkenhaus, A Marhold, T Matyus, O Maurhart, L Monat, S Nauerth, J-B Page, A Poppe, E Querasser, G Ribordy, S Robyr, L Salvail, A W Sharpe, A J Shields, D Stucki, M Suda, C Tamas, T Themel, R T Thew, Y Thoma, A Treiber, P Trinkler, R Tualle-Brouri, F Vannel, N Walenta, H Weier, H Weinfurter, I Wimberger, Z L Yuan, H Zbinden and A Zeilinger Stable quantum key distribution with active polarization control based on time-division multiplexing J Chen, G Wu, L Xu, X Gu, E Wu and H Zeng Controlling passively quenched single photon detectors by bright light Vadim Makarov Information leakage via side channels in freespace BB84 quantum cryptography Sebastian Nauerth, Martin Fürst, Tobias Schmitt-Manderbach, Henning Weier and Harald Weinfurter Standardization of quantum key distribution and the ETSI standardization initiative ISG-QKD Thomas Länger and Gaby Lenhart Entangled quantum key distribution with a biased basis choice Chris Erven, Xiongfeng Ma, Raymond Laflamme and Gregor Weihs Finite-key analysis for practical implementations of quantum key distribution Raymond Y Q Cai and Valerio Scarani Field test of a continuous-variable quantum key distribution prototype S Fossier, E Diamanti, T Debuisschert, A Villing, R Tualle-Brouri and P Grangier Physics and application of photon number resolving detectors based on superconducting parallel nanowires F Marsili, D Bitauld, A Gaggero, S Jahanmirinejad, R Leoni, F Mattioli and A Fiore Device-independent quantum key distribution secure against collective attacks Stefano Pironio, Antonio Acín, Nicolas Brunner, Nicolas Gisin, Serge Massar and Valerio Scarani 1310 nm differential-phase-shift QKD system using

  7. EDITORIAL: CAMOP: Quantum Non-Stationary Systems CAMOP: Quantum Non-Stationary Systems

    Science.gov (United States)

    Dodonov, Victor V.; Man'ko, Margarita A.

    2010-09-01

    QED. Another rapidly growing research field (although its origin can be traced to the beginning of the 1980s) is the quantum control of evolution at the microscopic level. These examples show that quantum non-stationary systems continue to be a living and very interesting part of quantum physics, uniting researchers from many different areas. Thus it is no mere chance that several special scientific meetings devoted to these topics have been organized recently. One was the international seminar 'Time-Dependent Phenomena in Quantum Mechanics' organized by Manfred Kleber and Tobias Kramer in 2007 at Blaubeuren, Germany. The proceedings of that event were published in 2008 as volume 99 of Journal of Physics: Conference Series. Another recent meeting was the International Workshop on Quantum Non-Stationary Systems, held on 19-23 October 2009 at the International Center for Condensed Matter Physics (ICCMP) in Brasilia, Brazil. It was organized and directed by Victor Dodonov (Institute of Physics, University of Brasilia, Brazil), Vladimir Man'ko (P N Lebedev Physical Institute, Moscow, Russia) and Salomon Mizrahi (Physics Department, Federal University of Sao Carlos, Brazil). This event was accompanied by a satellite workshop 'Quantum Dynamics in Optics and Matter', organized by Salomon Mizrahi and Victor Dodonov on 25-26 October 2009 at the Physics Department of the Federal University of Sao Carlos, Brazil. These two workshops, supported by the Brazilian federal agencies CAPES and CNPq and the local agencies FAP-DF and FAPESP, were attended by more than 120 participants from 16 countries. Almost 50 invited talks and 20 poster presentations covered a wide area of research in quantum mechanics, quantum optics and quantum information. This special issue of CAMOP/Physica Scripta contains contributions presented by some invited speakers and participants of the workshop in Brasilia. Although they do not cover all of the wide spectrum of problems related to quantum non

  8. Boosted-jet reconstruction methods in a search for Higgs-boson production in association with a top-quark-antiquark pair at the CMS experiment

    Energy Technology Data Exchange (ETDEWEB)

    Riese, Felix

    2017-01-31

    In 2012, the ATLAS and CMS collaborations discovered a new particle at the Large Hadron Collider (LHC). It is likely to be the Higgs boson predicted by the standard model of particle physics (SM). The Yukawa coupling between top quarks and the Higgs boson can be measured in the Higgs-boson production in association with a top-quark-antiquark pair (t anti tH). This thesis is based on a CMS t anti tH analysis at a center-of-mass energy of 13 TeV. The t anti tH decay is studied with the Higgs-boson decaying into a bottom-quarkantiquark pair and the t and anti t each decaying into a bottom quark and a W boson. One of the W bosons decays hadronically into two quarks, and one of the W bosons decays leptonically into a lepton and a neutrino. The focus of this thesis is the analysis of particles which decay hadronically into jets. If the mother particle has a large transverse momentum, the jets of the decay products are likely to merge into one large-radius jet. To reconstruct the substructure of these so-called boosted jets, substructure algorithms are implemented for the reconstruction of the boosted hadronically decaying top quark and the boosted Higgs boson. The main objectives of this thesis are to study the use of jets generated by the anti-κ{sub T} algorithm (ak4 jets) in the boosted reconstruction and possible improvements on the boosted Higgs-boson reconstruction. First, a geometric matching between ak4 jets and the subjets of the boosted object reconstruction was performed. Over 94% of all boosted candidate subjets can be matched with ak4 jets. Most of the non-matched candidate subjets are jets with a low transverse momentum. One interpretation is that most of these non-matched subjets occur from pileup. The high correlation of the b-tag discriminant output values of both ak4 jets and boosted candidate subjets shows that the b-tag discriminant corrections affect both ak4 jets and subjets similarly. This is a follow-up study on the thesis by Tobias Pfotzer. In

  9. Generation, ascent and eruption of magma on the Moon: New insights into source depths, magma supply, intrusions and effusive/explosive eruptions (Part 2: Predicted emplacement processes and observations)

    Science.gov (United States)

    Head, James W.; Wilson, Lionel

    2017-02-01

    , inhibiting dike emplacement and surface eruptions. In contrast to small dike volumes and low propagation velocities in terrestrial environments, lunar dike propagation velocities are typically sufficiently high that shallow sill formation is not favored; local low-density breccia zones beneath impact crater floors, however, may cause lateral magma migration to form laccoliths (e.g., Vitello Crater) and sills (e.g., Humboldt Crater) in floor-fractured craters. Dikes emplaced into the shallow crust may stall and produce crater chains due to active and passive gas venting (e.g., Mendeleev Crater Chain) or, if sufficiently shallow, may create a near-surface stress field that forms linear and arcuate graben, often with pyroclastic and small-scale effusive eruptions (e.g., Rima Parry V). Effusive eruptions are modulated by effusion rates, eruption durations, cooling and supply limitations to flow length, and pre-existing topography. Relatively low effusion rate, cooling-limited flows lead to small shield volcanoes (e.g., Tobias Mayer, Milicius); higher effusion rate, cooling-limited flows lead to compound flow fields (e.g., most mare basins) and even higher effusion rate, long-duration flows lead to thermal erosion of the vent, effusion rate enhancement, and thermal erosion of the substrate to produce sinuous rilles (e.g., Rimae Prinz). Extremely high effusion rate flows on slopes lead to volume-limited flow with lengths of many hundreds of kilometers (e.g., the young Imbrium basin flows). Explosive, pyroclastic eruptions are common on the Moon. The low pressure environment in propagating dike crack-tips can cause gas formation at great depths and throughout dike ascent; at shallow crustal depths both the smelting reaction and the recently documented abundant magmatic volatiles in mare basalt magmas contribute to significant shallow degassing and pyroclastic activity associated with the dike as it erupts at the surface. Dikes penetrating to the surface produce a wide range of

  10. E-publishing and multimodalities

    Directory of Open Access Journals (Sweden)

    Yngve Nordkvelle

    2008-12-01

    knowledge can be explored by the use of a tailor-made Information and Communication Technology (ICT-tool. In constructing content to this particular internet- based resource a clinician expert physiotherapist contributed with a detailed analysis of her own practice and its underpinning rationale, displayed by film and text simultaneously. The paper investigates the ways that led to how her "looking into her own practice" with "critical friends", mediated in a transparent mode showed a valuable learning potential for herself and others. Trine Ungermann Fredskild also presents a paper related to the health professions, namely nursing. In her paper "Distance learning students in "communities of practice" she investigates differences in attitudes among nursing students toward particular ways of performing their studies. She compares nursing education offered in three different learning programmes: full time, distance education students and credit transfer students and how they cope with issues of independent study, discipline of studying and cooperative activities. She demonstrates significant differences on a variety of factors and relates this also to how they use their respective Learning Management Systems.Tobias Werler presents a different style of educational reflection. In his paper "On the hidden curriculum of the mouse click: An anthropologically drama " he explores the philosophical and anthropological grounds of why media and ICT changes the ways we experience and learn in the digital age. It pinpoints the "click of the mouse" as one of the basic control options of how man and machine interact. Last we present a quantitative study of how Norwegian boys and girls use the Internet and mobile phones. In the paper titled: "Gender profiles of Internet and mobile phone use among Norwegian adolescents" the  group of authors, Reidulf G. Watten, Jo Kleiven, Knut Inge Fostervold, Halvor Fauskeand Frode Volden, look into gender profiles in the use of ICT among Norwegian

  11. The Dark Side of Nature: the Crime was Almost Perfect

    Science.gov (United States)

    2006-12-01

    Astrofisico di Arcetri, Italy), Guido Chincarini (INAF, Osservatorio Astronomico di Brera & Università degli Studi di Milano-Bicocca, Italy), Nino Panagia (Space Telescope Science Institute, USA), Gianpiero Tagliaferri, Dino Fugazza, Sergio Campana, Stefano Covino, and Paolo D'Avanzo (INAF, Osservatorio Astronomico di Brera, Italy), Daniele Malesani (SISSA/ISAS, Italy and Dark Cosmology Centre, Copenhagen), Vincenzo Testa, L. Angelo Antonelli, Silvia Piranomonte, and Luigi Stella (INAF, Osservatorio Astronomico di Roma, Italy), Vanessa Mangano (INAF/IASF Palermo, Italy), Kevin Hurley (University of California, Berkeley, USA), I. Felix Mirabel (ESO), and Leonardo J. Pellizza (Instituto de Astronomia y Fisica del Espacio). The Danish-led team is composed of Johan P. U. Fynbo, Darach Watson, Christina C. Thöne, Tamara M. Davis, Jens Hjorth, José Mará Castro Cerón, Brian L. Jensen, Maximilian D. Stritzinger, and Dong Xu (Dark Cosmology Centre, University of Copenhagen, Denmark), Jesper Sollerman (Dark Cosmology Centre and Department of Astronomy, Stockholm University, Sweden), Uffe G. Jørgensen, Tobias C. Hinse, and Kristian G. Woller (Niels Bohr Institute, University of Copenhagen), Joshua S. Bloom, Daniel Kocevski, Daniel Perley (Department of Astronomy, University of California at Berkeley, USA), Páll Jakobsson (Centre for Astrophysics Research, University of Hertfordshire, UK), John F. Graham and Andrew S. Fruchter (Space Telescope Science Institute, Baltimore, USA), David Bersier (Astrophysics Research Institute, Liverpool John Moores University, UK), Lisa Kewley (University of Hawaii, Institute of Astronomy, USA), Arnaud Cassan and Marta Zub (Astronomisches Rechen-Institut, Zentrum für Astronomie der Universität Heidelberg, Germany), Suzanne Foley (School of Physics, University College Dublin, Ireland), Javier Gorosabel (Instituto de Astrofisica de Andalucia, Granada, Spain), Keith D. Horne (SUPA Physics/Astronomy, University of St Andrews, Scotland, UK), Sylvio

  12. Editorial

    Directory of Open Access Journals (Sweden)

    Lars Råmunddal

    2015-11-01

    Full Text Available This second issue of Scandinavian Journal of Leadership and Theology (SJLT contains a total of seven peer-reviewed articles. Two of the articles focus on non-conformist ecclesiology; two papers discuss issues connected to how church development can be thought of and practiced today; and finally, the last three articles have leadership as their main theme. In the article Frikyrklig ecklesiologi (A Free Church Ecclesiology Fredrik Lindé discusses whether the Swedish Pentecostal pastor and author Peter Halldorf’s ecclesiology can really be regarded as non-conformist or whether it is more specifically seen as Baptist ecclesiology. It is well known that in recent years Halldorf has been inspired by ways of thinking about spirituality that are rooted in the Orthodox church tradition, a tradition that many perceive as quite far from the one Halldorf himself comes from. Lindé asks what the relationship is between the ‘Orthodox’ Halldorf and his Pentecostal-Baptist background and identity. What could a thorough understanding of Baptist ecclesiology inspired by the Baptist theologian John Howard Yoder have brought to Halldorf’s ecclesiastical thinking, Lindé asks. His response – and for that matter his suggestion to both Halldorf and the Swedish Pentecostal movement – is that Yoder could have deepened and entrenched Halldorf’s ecclesiology and understanding of spirituality in a theological tradition that is closer to his own than the Orthodox Church. In the article Evangelikalismen utfordret (Evangelism Challenged Bjørn Øyvind Fjeld discusses the theory of knowledge found in James K.A. Smith and indirectly in the Radical Orthodoxy movement. Fjeld’s analysis consists of a comparison between Smith’s theory of knowledge and that of the Evangelical theologian D.A. Carson. Fjeld uses Swedish theologian M. Stenmark’s theory of knowledge to evaluate the stances of Smith and Carson. Fjeld’s conclusion is that traditional Evangelicalism

  13. Seeking a Rational Approach to a Regional Refugee Crisis: Lessons from the Summer 2014 “Surge” of Central American Women and Children at the US-Mexico Border

    Directory of Open Access Journals (Sweden)

    Karen Musalo

    2017-03-01

    arrangements for unaccompanied children as required by federal law. Images of children crowded shoulder to shoulder in US Customs and Border Patrol holding cells generated a sense of urgency across the political spectrum (e.g., Fraser-Chanpong 2014; Tobias 2014. Responses to this “surge,” and explanations for it, varied widely in policy, media, and government circles. Two competing narratives emerged, rooted in two very disparate views of the “crisis.” One argues that “push” factors in the home countries of El Salvador, Honduras, and Guatemala drove children and families to flee as bona fide asylum seekers; the other asserted that “pull” factors drew these individuals to the United States. For those adopting the “push” factor outlook, the crisis is a humanitarian one, reflecting human rights violations and deprivations in the region, and the protection needs of refugees (UNHCR 2015b; UNHCR 2014; Musalo et al. 2015. While acknowledging that reasons for migration may be mixed, this view recognizes the seriousness of regional refugee protection needs. For those focusing on “pull” factors, the crisis has its roots in border enforcement policies that were perceived as lax by potential migrants, and that thereby acted as an inducement to migration (Harding 2014; Navarette, Jr. 2014. Each narrative, in turn, suggests a very different response to the influx of women and children at US borders. If “push” factors predominately drive migration, then protective policies in accordance with international and domestic legal obligations toward refugees must predominately inform US reaction. Even apart from the legal and moral rightness of this approach, any long-term goal of lowering the number of Central American migrants at the US-Mexico border, practically speaking, would have to address the root causes of violence in their home countries. On the other hand, if “pull” factors are granted greater causal weight, it would seem that stringent enforcement

  14. New Observations of Comet Hale-Bopp from La Silla

    Science.gov (United States)

    1998-10-01

    to the large size of the nucleus, probably 40 - 60 km in diameter, it will be possible to observe this comet with large optical telescopes for many years to come. Information about Hale-Bopp on the web Additional information about Comet Hale-Bopp is available on the web at many sites. Some of the most comprehensive websites may be accessed via the ESO Hale-Bopp site. Notes: [1] Other scientists involved in the long-term radio monitoring of Comet Hale-Bopp are Nicolas Biver (Institute for Astronomy, University of Hawaii, USA), Pierre Colom, Jacques Crovisier, Eric Gérard, Benoit Germain, Emmanuel Lellouch (Observatoire de Paris, France), Didier Despois (Observatoire de Bordeaux, France), Gabriel Paubert (IRAM, Granada, Spain), Raphael Moreno, Joern E. Wink (IRAM, Grenoble, France), John K. Davies (JAC, Hawaii, USA), William R.F. Dent (Royal Observatory, Edinburgh, UK), Hans Rickman, Marcus Gunnarsson (Uppsala Astronomiska Observatorium, Sweden), Per Bergman, Lars E.B. Johansson (OSO, Sweden), Fredrik Rantakyroe (SEST, La Silla), Darek C. Lis, David Mehringer, Dominic Benford, Martin Gardner, Tom G. Phillips (CSO, USA), Heike Rauer (DLR, Berlin, Germany). [2] The figure appears in N. Biver et al. : "Long-term Monitoring of the Outgassing of C/1995 O1 (Hale-Bopp) at Radio Wavelengths", a poster paper presented at the DPS meeting on October 11-16, 1998 (Madison, Wisconsin, USA) and to be published in Vol. 30 of the Bulletin of the American Astronomical Society . How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: http://www.eso.org ). ESO Press Photos may be reproduced, if credit is given to the European Southern Observatory.

  15. Editorial 01/2013 Normen und Normierungen

    Directory of Open Access Journals (Sweden)

    Christian Swertz

    2013-03-01

    Gottes normativ als wichtigste Instanz der Wahrheit begriffen haben, dem die Schrift untergeordnet war. Er rekapituliert dabei im Rekurs auf Michel Foucaults Ordnung der Dinge das moderne Aufkommen einer schrift- und d. h. am Alphabet orientierten Medientheorie etwa bei Jacques Derrida und Friedrich Kittler und expliziert die sozialdisziplinierende und normierende Rolle der Pädagogik, die bis in die Gegenwart reicht. Diese Normierungen existieren auch, so Friesen, in den aktuellen Debatten zur computeraffinen Generation der Digital Natives für die indes andere (medienkompetente Normen der (Medien-pädagogik gelten als für historische Generationen.Und so untersuchen auch Sascha Trültsch und Daniela Pscheida mit ihrem Beitrag die Frage nach Normen und Normierungen im Blick auf die Geschichte und Gegenwart des privaten Lebens. Dabei zeigen sie in vier Schritten, dass Privatheit etwa in der (publizistischen Fotografie seit jeher eine – auch skandalöse oder verletzende – Rolle gespielt hat und heben hervor, dass es dabei immer um normierende Mediennutzung ging und geht. Der Bereich des Geheimen und seiner Aufklärung wird dabei ebenso analysiert wie der Problembereich der kommunikativen Übertragung(en zwischen Privatem und Öffentlichem. So scheint mit der TV-Sendung Big Brother eine gläserne Durchsichtigkeit und Normierung der Intimität erreicht zu sein, die einen markanten Einschnitt in der Mediengeschichte der „veröffentlichten Privatheit“ darstellt, womit auch eine tiefe Veränderung normativer Konzepte einhergeht. Doch damit nicht genug, halten die AutorInnen anhand breiter empirischer Daten fest, dass wir es heute zwar mit Normverschiebungen und -lockerungen zu tun haben, nicht aber mit einer grundsätzlichen Auflösung von Normen und Normierungen in der Wissens- und Informationsgesellschaft.Hier setzen auch Christian Filk und Fredrik Gundelsweiler an, wenn sie analysieren, wie der seit Jahren anhaltende Technologisierungs- beziehungsweise

  16. List of Participants

    Science.gov (United States)

    2008-11-01

    WyderKatholieke Universiteit Leuven Ahmed YoussefAstroParticule et Cosmologie (APC), Université Paris Diderot Daniela ZanonUniversità Degli Studi di Milano Andrea ZanziPhysikalisches Institut, Universität Bonn Andrey ZayakinInstitute for Theoretical and Experimental Physics (ITEP), Moscow Tobias ZinggUniversity of Iceland Dimitrios ZoakosUniversidade de Santiago de Compostela Emanuele ZorzanUniversità di Milano Konstantinos ZoubosNiels Bohr Institute, København

  17. Authentic Learning Enviroment in Analytical Chemistry Using Cooperative Methods and Open-Ended Laboratories in Large Lecture Courses

    Science.gov (United States)

    Wright, John C.

    1996-09-01

    , etc. It requires a change in the way that faculty and students view themselves (4). It is clear that this course model is an example of one that replaces the traditional model of passive learners and inspired lecturers by a model where the students take an active and responsible part in the learning process and faculty members facilitate learning by preparing a learning environment that will challenge and empower students. These changes are fundamental and represent new traditions that guide students and faculty into a new approach to education. It is important to extend such approaches to other upper-level courses in the chemistry curriculum. Acknowledgment This work was supported by the National Science Foundation under grant 94-50615. Literature Cited 1. Moll, M. M.; Allen, R. D. J. College Sci. Teach. 1982, 11, 219-222. 2. Tobias, S. Revitalizing Undergraduate Science: Why Some Things Work and Most Don't; Research Corporation: Tucson, AZ, 1992. 3. Tobias, S. They're Not Dumb, They're Different: Stalking the Second Tier; Research Corporation: Tucson, AZ, 1990. 4. MacGregor, J. New Directions for Teaching and Learning 1990, 42, 19 -30. 5. Bunce, D.M. J. Chem. Educ. 1993, 70, 179 and associated papers. 6. Newmann, F. M. Phi Delta Kappan, 1991, 72, 458-463. 7. Walters, J. P. Anal. Chem. 1991, 63, 977A-985A, 1077A-1087A, 1179A-1191A. 8. Ricci, R. W.; Ditzler, M. A. J. Chem. Educ. 1991, 68, 228-232. 9. Laws, P. W. Physics Today, Dec. 1991, pp 24-31. 10. Pickering, M. J. Chem. Educ. 1985, 62, 874-875. 11. Alty, L. T. J. Chem. Educ. 1993, 70, 663-665. 12. Yamazaki, H.; Sperline, R. P.; Freiser, H. Anal. Chem. 1992, 64, 12720-2725. 13. Kagan, S. Cooperative Learning; Resources for Teachers, Inc.: San 1Juan Capistrano, CA, 1992. 14. Johnson, D. W. ; Johnson, R. T.; Smith, K. A. Active Learning: 1Cooperation in the College Classroom; Interaction Book Co.: Edina, 1MN, 1991. 15. Mazur, E. Peer Instruction: A User's Manual (Department of Physics, Harvard University, Cambridge

  18. Editorial

    Directory of Open Access Journals (Sweden)

    Fernando Mezadri

    2016-07-01

    ênero e a aprovar a paridade na composição das suas direções. Empregando uma série de técnicas de pesquisa diferentes na produção de dados, a autora conclui que mecanismos intrapartidários de reserva de vagas impactam de maneira rápida e assertiva a composição das direções partidárias, mas isolados não resolvem o problema da representação substantiva, pois há elementos de natureza simbólica e relacionados à divisão sexual do trabalho, que atuam como barreiras à atuação política das mulheres. Espraiando-se pela linha de estudos sobre diferenças e discriminação, Bruno Gontyjo de Couto publica ‘O debate sobre meio e raça na geração intelectual de 1870: a construção de um projeto de civilização para o Brasil’. Nesse texto, ele analisa desestruturas materiais e simbólicas erigidas no contexto do império do Brasil e a concomitante emersão da chamada geração intelectual de 1870 que assume a missão de formular análises e perspectivas sobre o país com intuito de se desenhar um caminho que constituiria o Brasil como um país civilizado. Em suas análises, esse grupo intelectual, encabeçado por Tobias Barreto, professor da escola de direito do Recife, descobre o “problema” da indefinição racial e da falta de integração nacional como obstáculos a serem superados nesse sentido, propondo uma série de projetos de intervenção. Escrito a quatro mãos, ‘Transexualidades: os rostos do estigma e da exclusão social’, resulta da pesquisa elabora por Jaime Alonso Caravaca Morera e Maria Itayra Padilha. Os autores fazem uma análise das diferentes manifestações do estigma e da exclusão social entre a população transexual. Munidos da noção de controle heterocisnormativo de orientação no patriacarcalismo, expõe os estigmas e exclusão no âmbito transexual derivados de aspectos pessoais, cognitivos, emocionais, estruturais e comportamentais que emergem como consequência direta da implantação da ideologia psiquiatrizante

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