75 FR 54656 - Government-Owned Inventions, Available for Licensing

Science.gov (United States)

2010-09-08

... availability of inventions for licensing. SUMMARY: Patent applications on the inventions listed below assigned..., Pasadena, CA 91109; telephone (818) 354-7770. NASA Case No.: NPO-46771-1: Diamond Heat-Spreader for...

75 FR 67985 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-11-04

... . Inhibition of Cell Motility, Angiogenesis and Metastasis Description of Invention: The present invention... SH2 domain-mediated interactions in the metastatic process and support the potential efficacy of this... Modality: Inhibition of cell motility-dependent processes, including angiogenesis and metastasis, in...

76 FR 18564 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-04-04

... Antibiotics: Naturally-Occurring Chrysophaetins and Their Analogues Description of Invention: This invention... the very limited number of new antibiotics developed in recent decades and the increased epidemic of infectious diseases. In fact, infectious diseases are the leading cause of death worldwide. In the United...

75 FR 44267 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-07-28

... inventions to extend market coverage for companies and may also be available for licensing. ADDRESSES..., PhD, at 301-435-3121 or [email protected] for more information. Software for Accurate Segmentation of Cell Nuclei in Breast Tissue Description of Invention: Automatic segmentation of cell nuclei is...

77 FR 31859 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-05-30

... inventions to extend market coverage for companies and may also be available for licensing. FOR FURTHER... three-dimensional segmentation approach for the quantitative interpretation of electron tomograms. IEEE...

76 FR 55069 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-09-06

... invention relates to an improved system for measuring bone mineral density (BMD). BMD measurement is an... vivo data available (animal) Inventors: Geraldo Kaplan (FDA), Krishnamurthy Konduru (FDA), et al...

75 FR 43992 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-07-27

... immune system may play an important role. This invention discloses that patients with AMD gain additional... of age related macular degeneration. This is in light of new findings that immune mechanisms appear...

78 FR 38352 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-06-26

...). The invention rat is superior to AD mice models because the rat has a larger sized brain to.... Licensing Contact: Patrick McCue, Ph.D.; 301-435-5560; [email protected] . Collaborative Research...

75 FR 44270 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-07-28

... belongs to a group of disorders in which the immune system may play an important role. This invention... agents in the treatment of age related macular degeneration. This is in light of new findings that immune...

75 FR 58401 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-09-24

..., attention deficit hyperactivity disorder (ADHD), and schizophrenia. Development of selective pharmacological... bipolar disorder, attention deficit disorder (ADD), and autism. Applications Method of diagnosis and... Disorders Description of Invention: The inventors have isolated and characterized an alkaloid, phantasmidine...

75 FR 58404 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-09-24

... the indicated licensing contact at the Office of Technology Transfer, National Institutes of Health... disorders (see above Description of Invention). Please contact NHGRI Technology Development Coordinator... for alcohol and drug addiction. Neuropsychiatric disorders including, for example, mood, anxiety...

76 FR 49777 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-08-11

... repress cell activation targets. Immunotherapy, although an effective treatment strategy, sometimes fails... inventions to extend market coverage for companies and may also be available for licensing. ADDRESSES... Target Validation Laboratory, DCTD, NCI, NIH, is seeking statements of capability or interest from...

78 FR 16690 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-03-18

... Ionizing Radiation Description of Technology: The invention relates to methods of using ketogenic compounds to protect against the adverse effects of radiation exposure, including ionizing radiation tissue... therapeutic efficacy of radiation therapies by protecting non-target tissues from incidental radiation damage...

78 FR 78370 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-12-26

... have developed a research tool, a murine cell line model (JygMC(A)) with a reporter construct, of... marrow transplantation, stem cell therapy, tissue regeneration) Competitive Advantages: Labeling markers... federally-funded research and development. Foreign patent applications are filed on selected inventions to...

78 FR 73549 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-12-06

... extend market coverage for companies and may also be available for licensing. FOR FURTHER INFORMATION... resistance due to the high sequence conservation of the target. More stable than thioesters. Development... makes this invention a novel and potential long-term therapeutic for restoration of exocrine gland...

78 FR 37554 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-06-21

... generation of self-renewing cells with a high proliferative capacity. Induced pluripotent stem cells (iPS... invention relates to a method of using CD47-modulating compounds to induce multipotent stem cells without..., please contact Denise Crooks at [email protected] . Method of Inducing Pluripotent or Multipotent...

75 FR 12764 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-17

..., lung, mammarys and kidney cancers. These mouse models serve as vehicles to test the efficacy of new... inventions to extend market coverage for companies and may also be available for licensing. ADDRESSES... applications. Spontaneously Transformed Mouse Epithelial Cancer Cell Lines Serving as Mouse Models: A New Model...

76 FR 40381 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-07-08

... inventions to extend market coverage for companies and may also be available for licensing. ADDRESSES... effective treatment option. EGFRvIII CARs can cross the blood-brain barrier, are expected to target only... squamous cell carcinomas. A personalized cancer treatment strategy for patients whose tumor cells express...

75 FR 21634 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-04-26

... interventional devices for delivery of drugs, cells, energy, or sutures through complex trajectories of the body... Ligands for Live Cell Imaging Description of Invention: Recently-developed protein tags enable the..., to fusion proteins containing these tags. For example, SNAP and CLIP tags bind O\\6\\-benzylguanine...

75 FR 26258 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-05-11

....gov for more information. Parvovirus B19 Codon Optimized Structural Proteins for Vaccine and Diagnostic Applications Description of Invention: Parvovirus B19 (B19V) is the only known pathogenic human parvovirus. Infection by this viral pathogen can cause transient aplastic crisis in individuals with high red...

75 FR 41501 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-07-16

... applications. A Transgenic Model of Human Basal Triple Negative Breast Cancer [C3(l)- tag mice] Description of Invention: Basal triple-negative breast cancer (TNBC) is a common form of human breast cancer for which..., causes a painful stimulation and incapacitates a person for only a brief period. This technology may...

76 FR 72713 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-11-25

...; Availability for Licensing AGENCY: National Institutes of Health, Public Health Service, HHS. ACTION: Notice... are thought to play a central role in this process. The subject invention is a novel method of... (CTLA4IgG) fusion protein to salivary glands. The system effectively blocks CTLA4 ligand interactions with...

78 FR 48692 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-08-09

... federally-funded research and development. Foreign patent applications are filed on selected inventions to... disrupts lipid homeostasis in liver. J Biol Chem. 2010 Apr 2;285(14):10880-9. [PMID 20097939]. Intellectual Property: HHS Reference No. E-465-2013/0--Research Tool. Patent protection is not being pursued for this...

75 FR 70010 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-11-16

... Appella (NCI), John K. Inman (NIAID), Deyun Wang (NIDDK), Lisa M. Miller Jenkins (NCI), Ryo Hayashi (NCI). Publications: 1. Miller Jenkins LM, et al. Nature Chemical Biology, in press. 2. Miller Jenkins LM, et al..., evaluate, or commercialize this invention. Please contact Dr. Henry Eden at [email protected] for more...

75 FR 12761 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-17

... inventions to extend market coverage for companies and may also be available for licensing. ADDRESSES..., ADP-ribosylated HNP-1 and other defensins are degraded rapidly in vivo due to the susceptibility of... at the level of approximately $6 billion a year and is expected to grow to $13 billion by the year...

76 FR 76741 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-12-08

... conditional knockout mutation can be cross-bred using, for example, Cre-expressing mice to generate tissue... anisotropy in yeast cells using double- pulsed field gradient MR. NMR Biomed. 2011 July 22. E-pub ahead of...

77 FR 69866 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-11-21

... system; (2) extracellular matrix remodeling; (3) moderation of inflammation by reducing levels of... is governed in large part by the regulation of host cell death. Lipid mediators called eicosanoids...

76 FR 15326 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-03-21

... Wnt signaling, which plays a role in kidney, lung, and vascular development, and they are likely to... protein involved in the signaling pathway of IL-17 cytokines. Interaction between CIKS and tumor necrosis...

77 FR 29668 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-05-18

... there are only three known A subtypes of influenza viruses (H1N1, H1N2, and H3N2) currently circulating... for Detection and Subtyping of Human Influenza Viruses Description of Technology: Available for licensing and commercial development are a novel influenza virus microarray and methods for using the...

76 FR 44939 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-07-27

... colorectal carcinomas, endometrial cancers and leukemia, particularly acute myeloid leukemia. Thus, huN-CoR is a potentially-valuable tool for cancer diagnosis, as well as a target for the development of huN.... Applications: Target for novel anti-cancer therapies. Use as a tool for prognosis and diagnosis of HuN-Cor...

75 FR 8313 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Science.gov (United States)

2010-02-24

... ``Method for producing Nanoparticles''; U.S. Patent Application Number 12/471,607 filed on May 26, 2009..., Business and Partnership Office, Office of Research and Technology Applications, Building 505, 22473... CONTACT: Mr. Paul Fritz, Office of Research and Technology Applications, Building 505, Naval Air Warfare...

75 FR 57274 - Financial Management and Assurance; Government Auditing Standards

Science.gov (United States)

2010-09-20

... GOVERNMENT ACCOUNTABILITY OFFICE Financial Management and Assurance; Government Auditing Standards.... Dalkin, Director, Financial Management and Assurance. [FR Doc. 2010-23374 Filed 9-17-10; 8:45 am] BILLING... financial and performance auditing drawn from all levels of government, private enterprise, public...

75 FR 75177 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-12-02

.... Adoptive immunotherapy is a promising new approach to cancer treatment that engineers an individual's... ten (10) known members of the SSX protein family designated SSX-1 through SSX-10. The T cell receptors... family members, including SSX-3, SSX-4, SSX-5, SSX-9, and/or SSX-10, and deliver a productive...

76 FR 10375 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-02-24

... epitopes. Cancer Immunol Immunother. 2010 Sept. 21, E-pub ahead of print, doi: 10.1007/s00262- 010-0916-z..., doi:10.1371/ journal.pbio.0030087. [PubMed: 15757365] Patent Status: Issued Australian Patent No...

78 FR 43216 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-07-19

... tissue for grafting. Potential Commercial Applications: Tissue engineering. Simulation of physiological... Lett. 2012 Oct 10;12(10):5192-5. [PMID 23016824]. 2. Grabow WW, et al. ``RNA Nanotechnology in Nanomedicine,'' in Nanomedicine and Drug Delivery (Recent Advances in Nanoscience and Nanotechnology), ed. M...

50 CFR 14.17 - Personally owned pet birds.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Personally owned pet birds. 14.17 Section 14.17 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR... Ports § 14.17 Personally owned pet birds. Any person may import a personally owned pet bird at any port...

75 FR 8082 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-02-23

... glycosyltransferases that can transfer a sugar residue with a chemically reactive functional group to N... carrying sugar moieties with reactive groups that can be used in the assembly of bio-nanoparticles to... . Collaborative Research Opportunity: The National Cancer Institute's Nanobiology Program is seeking statements of...

78 FR 28857 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-05-16

... need of lymphodepletion and exogenous cytokine support. Development Stage: Pre-clinical In vitro data... Chem Biol. 2012 Oct;8(10):839-47. [PMID 22922757] 2. Anastasiou D, et al. Inhibition of pyruvate kinase...

76 FR 61717 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-10-05

... Aug 30; 5(8): e1299; doi:10.1371/journal.pntd.0001299. 2. Klion AD, et al. Cloning and... untoward clinical events. Development Stage: Prototype. Inventors: James M. DeLeo and Patricia P. Sengstack...

77 FR 13344 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-03-06

... tumour necrosis factor alpha and systemic immune activation. Ann Rheum Dis. 2008 Oct;67(10):1437-1443... metastatic potential of these cells Identify transcription factors/genes activated in the tumor... tumor cells expressed at low frequency within a tumor and are resistant to conventional chemotherapies...

43 CFR 17.10 - Judicial review.

Science.gov (United States)

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Judicial review. 17.10 Section 17.10... Origin § 17.10 Judicial review. Action taken pursuant to section 602 of the act is subject to judicial review as provided in section 603 of the act. [29 FR 16293, Dec. 4, 1964] ...

10 CFR 784.5 - Waiver of identified inventions.

Science.gov (United States)

2010-01-01

... contractor has made or will make substantial investment of financial resources or technology developed at the contractor's private expense which will directly benefit the commercialization of the invention; (g) The... extent to which the Government has contributed to the field of technology of the invention; (e) The...

17 CFR 10.105 - Review by Commission on its own initiative.

Science.gov (United States)

2010-04-01

... own initiative. 10.105 Section 10.105 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... initiative. The Commission may on its own initiative, within 30 days after the initial decision has been... the Commission has directed review on its own initiative shall be served on all parties by the...

48 CFR 23.704 - Application to Government-owned or -leased facilities.

Science.gov (United States)

2010-10-01

... ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Application to Government... and Services 23.704 Application to Government-owned or -leased facilities. Executive Order 13101...

STATE-OWNED RURAL BANK PERFORMANCE: DO GOVERNMENT OWNERSHIP AND CORPORATE GOVERNANCE UNIQUENESS MATTER?

Directory of Open Access Journals (Sweden)

Azilsyah Noerdin

2016-12-01

Full Text Available It has been widely recognized that ownership structure has an impact on firm performance. This paper examines whether rural banks owned by government have poorer performance than those owned by private parties with the emphasis on corporate governance uniqueness of state-owned rural banks. 42 rural banks in Indonesia has been selected as the sample. MANOVA test is used to investigate the difference performance between the two types of the rural banks. The results show that state-owned rural banks perform poorer than their privately-owned counterparts. It is indicated by lower ROA ratio and higher OEOI and NPL ratios. The important implication of this finding suggets that government ownership impede boards of rural banks to implement good corporate governance practices in order to improve their banks performance.

75 FR 54346 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-09-07

... beam splitter of the technology include one or more pairs of axicons (also known as conical lenses... viruses (e.g. HIV, influenza, or hepatitis virus), bacteria (e.g. Listeria monocytogenes), or prozoans...

75 FR 81626 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-12-28

... include cardiac cells or cardiac-like cells derived from embryonic stem cells or mesenchymal stem cells... of federally-funded research and development. Foreign patent applications are filed on selected... irregularly or rarely spontaneously active cells into pacemakers generating rhythmic excitations. [[Page 81627...

76 FR 33769 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-06-09

... Application No. 61/452,364 filed March 14, 2011 (HHS Reference No. E-063-2011/0-US-01). Licensing Status...[alpha]-Targeted Therapy for Diabetes and Obesity Description of Technology: This technology describes... and treatment of diabetes. In obesity, the rapid expansion of adipose tissue outpaces the oxygen...

75 FR 81628 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-12-28

... National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), part of the National Institute of... 2010 (HHS Reference No. E-116-2010/0-US-01). Licensing Status: Available for licensing. Licensing...; [email protected] . Collaborative Research Opportunity: The National Institute of Diabetes and...

76 FR 36553 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-06-22

... Application No. 61/473,610 filed 08 Apr 2011 (HHS Reference No. E-129-2011/0-US-01). Licensing Status... be used for inducing immune suppression for autoimmune diseases like type I diabetes or multiple... diseases like type I Diabetes or Multiple sclerosis, where known target antigens have been identified...

75 FR 66106 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-10-27

... and HCC stem-cell subtype. Subsets of this metabolite/gene signature can distinguish HCC tumors from... early stage is defined as TNM stage I, prognose negative patient outcome, and identify a HCC stem cell... of Federally-funded research and development. Foreign patent applications are filed on selected...

76 FR 18561 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-04-04

... nanocomplexes) can effectively label stem cells, immune cells, tumor cells, or any other therapeutically... Clinical-- Cell-based therapy (e.g. stem cells, or immune cells therapy, genetic engineered cells); monitoring and [[Page 18563

75 FR 10286 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-05

... resulted in decreased apoptosis in irradiated tissues at 24 hours, preservation of hematopoietic stem cell... of federally-funded research and development. Foreign patent applications are filed on selected... development programs based on this approach and many research laboratories around the world conduct research...

76 FR 25697 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-05-05

.... Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell... of federally-funded research and development. Foreign patent applications are filed on selected... system that has been depleted by infection (e.g., HIV), chemotherapy, or progenitor cell transplantation...

77 FR 19299 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-03-30

... aggressive form of HCC, hepatic stem cell-like HCC subtype (HpSC HCC), which retains stem-cell features... of federally-funded research and development. Foreign patent applications are filed on selected... applications. MUC-1 Tumor Antigen Agonist Epitopes for Enhancing T-cell Responses to Human Tumors Description...

78 FR 3437 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-01-16

... dramatically improve research insights and the effectiveness of cell-based therapies. Zirconium-89 (\\89\\Zr) has... cells, natural killer T-cells, macrophages, dendritic cells, and stem cells, have been produced and... technology may significantly improve cell therapies, cell level diagnostics and aid research for non-cell...

75 FR 77884 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-12-14

... developments for various cancers. Diagnostic assays for various cancers. Regulation of embryonic stem cell... embryonic stem cells and/or cancer cells. Inventors: Matthew Boxer (NHGRI-NCGC); Min Shen (NHGRI-NCGC); Doug... of federally-funded research and development. Foreign patent applications are filed on selected...

78 FR 24756 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-04-26

..., Ph.D. at [email protected] . Novel Methods for Generating Retinal Pigment Epithelium Cells From Induced Pluripotent Stem Cells Description of Technology: High efficiency methods for producing retinal pigment epithelial cells (RPE) from induced pluripotent stem cells (iPSCs) are disclosed. The RPE is a...

77 FR 48997 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-08-15

.... Structuring feature space: a non- parametric method for volumetric transfer function generation. IEEE Trans... therapies for treating AMD focus on generating RPE cells from stem cells. This GPF-based plasmid can be inserted into growing stem cells, and the fluorescence marker can be used to detect and purify stem cells...

75 FR 10280 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-05

... has been demonstrated for this technology in dog and guinea pig models. Potential Applications and... effects in dogs and guinea pigs. J Clin Invest. 2009 Aug;119(8):2271-2280. [PubMed: 19620788] Patent.... Development of an siRNA-based therapy for ovarian cancer. Development Status: Discovery stage. Market: Ovarian...

75 FR 29766 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-05-27

... extremely useful for comparative biochemical analyses of cell culture systems in which the FLCN gene is... low to be detected by the aforementioned techniques. Available for licensing is an optimized an ISH... more than eight percent of total global pharmaceutical sales. [[Page 29768

77 FR 11137 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-02-24

... epithelial cells within a plane orthogonal to their apical-basal axis. Disruption of core PCP proteins leads... heterogeneity in physiological responses to chronic alcohol consumption. The inventors of the present technology...

78 FR 71625 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-11-29

... available. In vivo data available (animal). Inventors: Dimiter S. Dimitrov (NCI), Zhu Zhongyu (NCI), Pradman... . Collaborative Research Opportunity: The National Cancer Institute, Laboratory of Human Carcinogenesis, is... studies are of great importance for future pre-clinical and clinical studies of MJC13. Potential...

76 FR 66727 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-10-27

... this viral pathogen can cause transient aplastic crisis in individuals with high red cell turnover, pure red cell aplasia in immunosuppressed patients, and hydrops fetalis during pregnancy. In children, B19V most commonly causes erythema infectiosum, or fifth's disease. Infection can also cause...

76 FR 4921 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-01-27

... detection of other (protein, tissue, biochemical, or chemical) microarrays. Applications: DNA microarrays... patients, but it often ultimately fails to cure the disease since cancer cells can become resistant to the... effect of antitumor agents. Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a DNA repair enzyme involved in the...

75 FR 50768 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-08-17

... multiple functionalities. This technology provides a novel mechanism to treat a number of disorders related... of Diabetes and Digestive and Kidney Diseases, Laboratory of Bioorganic Chemistry, Molecular...

76 FR 22109 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-04-20

... properties. It plays a pivotal role in antitumorigenesis induced by chemopreventive compounds. Transgenic..., Swoger J, Stelzer EH. Basic building units and properties of a fluorescence single plane illumination microscope. Rev Sci Instrum. 2007 Feb;78(2):023705. [PubMed: 17578115] 3. Fahrbach F, Rohrbach A. Microscopy...

75 FR 10285 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-05

... fractures or bone degenerative diseases. Applications: Injectable bone-filling materials. Artificial bone... bone-filling materials, and enhancement of new bone generation. This composition has demonstrated.... Use of Modified Peptide Nucleic Acids for Visualizing DNA Description of Technology: The compounds...

76 FR 51376 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-08-18

... Computed Tomography Description of Technology: Vertebral fractures due to osteoporosis result in loss of... humanization required. Highly potent neutralizing antibodies. Biological materials available. Development Stage...; [email protected] . Methods of Treating Giardiasis Using FDA-Approved Compounds Description of...

78 FR 8547 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-02-06

... Prickett (NHGRI), and Steven Rosenberg (NCI). Publication: Prickett TD, et al. Exon capture analysis of G... Steven Rosenberg (NCI) Publication: Prickett TD, et al. Exon capture analysis of G-protein coupled... Steven Rosenberg (NCI) Publication: Cronin JC, et al. Frequent mutations in the MITF pathway in melanoma...

77 FR 40073 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-07-06

... Immunotherapy. For collaboration opportunities, please contact Steven A. Rosenberg, M.D., Ph.D. at [email protected], Richard A. Morgan, Steven A. Rosenberg (all of NCI). Intellectual Property: HHS Reference No. E-105-2012/0... contact Steven A. Rosenberg, M.D., Ph.D. at [email protected] . Antagonists of Hyaluronan Signaling for...

78 FR 20667 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-04-05

... serum/plasma testing could be used as a clinical marker of HIV disease status to predict/monitor the...-pass optical filter, digital camera, and electronic triggering system. Potential Commercial...

75 FR 55799 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-09-14

... licensing. Licensing Contact: Patrick P. McCue, PhD, (301) 435-5560; [email protected] . Collaborative... Reference No. E-051-2010/0-US-01). Licensing Status: Available for licensing. Licensing Contact: Patrick P... for the brain tumors or brain cancers indentified as gliomas, glioblastomas, or astrocytomas. This...

75 FR 4571 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-01-28

.... Applications: Therapies for tumors associated with NF1 (including brain and peripheral nervous system tumors...-US-01). Licensing Status: Available for licensing. Licensing Contact: Patrick P. McCue, Ph.D.; 301...

75 FR 63841 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-10-18

..., March 1996. 2. Du X, Dunxu Y, Cuihua L, Jing L. ``A novel approach to SVD-based image filtering...-4616; [email protected] . John Stansberry, PhD; 301-435-5236; [email protected] . Collaborative Research... from parties interested in collaborative research to implement the technology described above on...

75 FR 4570 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-01-28

... Y, Cuihua L, Jing L. ``A novel approach to SVD-based image filtering improvement,'' International... Stansberry, Ph.D.; 301-435-5236; [email protected] . Collaborative Research Opportunity: The National... in collaborative research to implement the technology described above on specific commercial...

75 FR 4569 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-01-28

... States this year. Women will be disproportionately affected constituting 76% of these new cases... to develop more accurate diagnostic tests to detect thyroid cancer. Inventors: Steven K. Libutti (NCI... necessarily limited to, cancer, inflammation, and tumor progression or regression. Inventors: Thomas H. Bugge...

75 FR 989 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-01-07

..., but may be triggered to proliferate through largely unknown factors. Inventors at the National... 192,370 women will be diagnosed with and 40,170 women will die of cancer of the breast in 2009... high probability of recurrence of metastatic disease leading to mortality. Inventors: Dalit Barkan and...

75 FR 66108 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-10-27

...; Availability for Licensing AGENCY: National Institutes of Health, Public Health Service, HHS. ACTION: Notice... immunological response to bacterial antigens in the gut microflora is thought to be involved. Present treatments... previous work, scientists at NIAID and FDA have shown that an Il-13 chimeric fusion protein linked to an...

77 FR 26294 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-05-03

...; Availability for Licensing AGENCY: National Institutes of Health, Public Health Service, HHS. ACTION: Notice.... Multiple myeloma is a malignancy of plasma cells. It is almost always incurable. A CAR is a fusion protein... mammalian cells. The toxicity thought to be a result of inhibition of multiple essential mammalian...

76 FR 10378 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-02-24

... the indicated licensing contact at the Office of Technology Transfer, National Institutes of Health... Residues From Recombinant Proteins Description of Technology: Affinity tags are commonly used to facilitate... inventors have now cloned, expressed and purified bovine carboxypeptidase B (BoCPB), which is specific for...

76 FR 55071 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-09-06

... Diagnosis of Autoimmune Inflammatory Diseases Description of Technology: Autoimmune inflammatory diseases... leukemia carcinomas. Research regent to study IGF-I and/or IGF-II binding and its association with tumor...

75 FR 66104 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-10-27

...--Expressing Leukemia Cells''. PCT Patent Application WO 2007/016150--``Mutated Pseudomonas Exotoxins with... development and to identify potential molecular targets for the diagnosis, prevention, and treatment of cancer... cancer diagnosis, prevention, and treatment. Testing kinase inhibitors and other novel drugs being...

78 FR 29388 - Government-Owned Inventions, Available for Licensing

Science.gov (United States)

2013-05-20

... Display and Decision Support Interface; NASA Case No.: ARC-16337-1: Method and Device for Biometric Subject Verification and Identification Based Upon Electrocardiographic Signals; NASA Case No.: ARC 16812...

77 FR 36282 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-06-18

... S, et al. Polymeric nanoparticle-based activatable near-infrared nanosensor for protease... consisting of one variant alpha subunit, which is soluble, and one invariant beta subunit, which is membrane...

77 FR 18833 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-03-28

... for microbial analytes identification via spectral pattern recognition. The device design includes a... cellular protein necessary for HCV replication and not the virus itself, the emergence of viral resistance.... In vitro data available. In vivo data available (animal). Inventors: Yves G. Pommier, Robert H...

77 FR 60442 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-10-03

... of Child Health and Human Development is seeking statements of capability or interest from parties..., such as organ graft rejection, type 1 diabetes and multiple sclerosis. Prior to transfusion, adoptive... autoimmune diseases, such as Graft vs. Host Disease, Organ Graft Rejection Type 1 Diabetes, Multiple...

76 FR 30731 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-05-26

.... Investigators at the Eunice Kennedy Shriver National Institute of Child Health and Human Development have... Shriver National Institute of Child Health and Human Development, Section on Cellular Neurobiology, is...-Glucosidase Chaperones and Inhibitors for Treatment of Pompe Disease and Type 2 Diabetes Description of...

78 FR 35290 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-06-12

... surface markers: programmed cell death protein 1 (PD-1; CD279), 4-1BB (CD137), T cell Ig- and mucin-domain... lack of suitable methods for screening hundreds, or even thousands, of cells expressing such proteins...) encodes a mammalian secreted protein comprising the same amino acid sequence. Synalleles are variants of a...

78 FR 56720 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-09-13

...: Prototype. In vivo data available (animal). In vivo data available (human). Inventors: Robert Lederman and... data available (animal). Inventors: Anu Puri (NCI) et al. Publications: 1. Yavlovich A, et al. Design... application in large part because delivery technologies for these therapies are not effective. Most nucleic...

78 FR 5818 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-01-28

... collaborative research to further develop, evaluate or commercialize retinoid-related orphan receptors (RORs... therapeutic agents Possible to follow the cell killing process in real time, using fluorescence lifetime...

77 FR 3273 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-01-23

... Technology: Available for licensing is a novel method using short-term treatment with a glucocorticoid...: Licensing information and copies of the U.S. patent applications listed below may be obtained by writing to... into memory cells and terminally differentiated plasma cells. Moreover, IL-21 has anti-tumor activity...

77 FR 54935 - Government-Owned Inventions, Available for Licensing

Science.gov (United States)

2012-09-06

... and Mobile Structures; NASA Case No.: LEW-17458-2: Compact Solid State Entangled Photon Source; NASA...; NASA Case No.: LEW-18248-1: Cellular Reflectarray Antenna and Method of Making Same; NASA Case No.: LEW...

77 FR 70788 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-11-27

...) within the HIV Gag protein and elicit strong, cross-clade cellular and humoral responses. The DNA vaccine... sequences elicited strong, cellular T-cell and humoral antibody immune responses. The Gag-specific antibody..., the ability to inhibit this process can be used to limit growth of solid tumors and as a therapy for...

77 FR 54578 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-09-05

... Endothelial Growth Factor-A (VEGF-A) is an angiogenic agent that drives blood vessel formation in solid tumors... antagonizes all VEGF-A-stimulated signaling events. Potential Commercial Applications: Therapy for solid...) that block signal transduction and associated cellular responses by competitive displacement of native...

75 FR 60761 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-10-01

... related to drug resistance. Inventors: Genbin Shi, Gary Shaw, Xinhua Ji (NCI). Patent Status: U.S... Publications: 1. Blaszczyk J, Shi G, Li Y, Yan H, Ji X. Reaction trajectory of pyrophosphoryl transfer...: 15016362]. 2. Blaszczyk J, Shi G, Yan H, Ji X. Catalytic center assembly of HPPK as revealed by the crystal...

77 FR 9668 - Government-Owned Inventions; Availability for Licensing

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2012-02-17

... of a histidyl residue under Mitsunobu conditions and synthesis of orthogonally protected histidine... during such conditions as diabetes, osteoporosis, menopause, hypertension, metabolic syndrome, chronic...

77 FR 12316 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-02-29

... to treat or prevent Secondary-progressive multiple sclerosis (SP-MS). Competitive Advantages: This... marrow transplantation as we do it today. Rather than using the current non-selective agent G-CSF (which... infiltrates at sites of inflammation. Competitive Advantages: Mobilization of HSPCs yielding high-level...

78 FR 59039 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-09-25

... molecules that act on the same cannabinoid receptors that recognize and mediate the effects of marijuana...: pharmacologically induced synthetic lethality. Cancer Cell. 2013 Feb 11;23(2):228-37. [PMID 23352416]. Intellectual...

76 FR 59410 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-09-26

...: Licensing information and copies of the U.S. patent applications listed below may be obtained by writing to...-402-0220. A signed Confidential Disclosure Agreement will be required to receive copies of the patent... to menopause, birth control, menstrual cycle/amenorrhea, fertility or endometriosis. Competitive...

75 FR 51823 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-08-23

...: Licensing information and copies of the U.S. patent applications listed below may be obtained by writing to.../402-0220. A signed Confidential Disclosure Agreement will be required to receive copies of the patent... infertility and irregular menstrual periods than in healthy women. The discovery of MATER as an important...

75 FR 10282 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-05

... Philadelphia chromosome-positive (Ph+) cancers like chronic myeloid leukemia (CML). Although imatinib is highly... Contact: Sabarni Chatterjee, Ph.D.; 301-435-5587; [email protected] . Collaborative Research Opportunity: The National Cancer Institute, Transport Biochemistry Section, Laboratory of Cell Biology, is...

77 FR 3275 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-01-23

... prognosis of ADHD treatments. In addition, signaling pathways delineated from these genetic sites can be... prediction of ADHD susceptibility, severity, and possibly patient response to treatment. Development Stage... treatment. Potential Commercial Applications Therapeutic for the treatment of various human diseases...

76 FR 4920 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-01-27

... sequences of microRNAs. The application also claims live attenuated chimeric flaviviruses, where the first... appear to be distinct from each other. Available for licensing is a Plk1 ELISA assay using peptide...

78 FR 24758 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-04-26

... metabolites in the urine of mice strongly correlated with tumor formation and reflected the progressive... special significance in a wide variety of biological and biomedical fields, which could lead the discovery... protein was recently shown to be encoded by the clag3 gene. This discovery opens the possibility of...

78 FR 57664 - Government-Owned Inventions, Available for Licensing

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2013-09-19

... Temperature and Fatigue Resistant Environmental Barrier Coating Bond Coat Systems for SiC/SiC Ceramic Matrix Composites; NASA Case No.: LEW-18844-1: Electrospun Nanofiber Coating of Fiber Materials: A Composite... Regulators; NASA Case No.: LEW-18964-1: High Temperature Lightweight Self- Healing Ceramic Composites for...

75 FR 63840 - Government-Owned Inventions; Availability for Licensing

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2010-10-18

... applications. Prevention and Treatment of Herpes Virus Infection by Inhibition of the JMJD2 Family of Histone..., shingles, CMV disease, mononucleosis, and Kaposi's sarcoma. Applications: Prevention or treatment of... of federally-funded research and development. Foreign patent applications are filed on selected...

77 FR 34392 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-06-11

... pneumonia viruses, and other viral infections. Potential Commercial Applications: Prevention and treatment... of federally-funded research and development. Foreign patent applications are filed on selected... INFORMATION: Licensing information and copies of the U.S. patent applications listed below may be obtained by...

77 FR 64810 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-10-23

... of improving the activity of topical antibiotics. Currently available topical antibiotic formulations... contact John Hewes, Ph.D. at [email protected] . Antimalarial Inhibitors That Target the Plasmodial... against malaria. Potential Commercial Applications: Antimalarial Drugs. Malaria Vaccine. Competitive...

75 FR 21636 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-04-26

... thermophilic enzymes for use in ancient and damaged DNA analysis and for novel applications with modified... effective study of ancient DNA and for use in forensic medicine. These enzymes are ubiquitous and are found... are of particular interest because the enzymes isolated from such species tend to be more stable, easy...

75 FR 29763 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-05-27

... Craniofacial Research, Laboratory of Sensory Biology, Neurobiology and Pain Therapeutics Section, is seeking... painstaking (and sometimes clumsy) manual dissection using needles or other micro-manipulation [[Page 29765...

75 FR 28664 - Government-Owned Inventions, Available for Licensing

Science.gov (United States)

2010-05-21

...; telephone (650) 604-5104; fax (650) 604-2767. NASA Case No. ARC-14653-1: Air Traffic Management Evaluation Tool (FACET). NASA Case No. ARC-16320-1: Model-Based Prognostics for Batteries. NASA Case No. ARC-16342-1: Advanced Sensor Technology for Algai Biotechnology (ASTAB). NASA Case No. ARC-16370-1: A Truss...

77 FR 57596 - Government-Owned Inventions, Available for Licensing

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2012-09-18

...; NASA Case No.: MFS-32865-4: Airfoil-Shaped Fluid Flow Tool for Use in Making Differential; NASA Case No...-32865-3: Star-Shaped Fluid Flow Tool for Use in Making Differential Measurements; NASA Case No.: MFS... 35812; telephone (256) 544-0013; fax (256) 544-0258. SUPPLEMENTARY INFORMATION: NASA Case No.: MFS-32757...

77 FR 54936 - Government-Owned Inventions, Available for Licensing

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2012-09-06

... POLARIZED MICROWAVE ANTENNA ELEMENT; NASA Case No.: GSC-14873-1: ADR SALT PILL DESIGN AND CRYSTAL GROWTH PROCESS FOR HYDRATED MAGNETIC SALTS; NASA Case No.: GSC-15660-1: SYSTEM, TOOL AND METHOD FOR INTEGRATED CIRCUIT AND COMPONENT MODELING; NASA Case No.: GSC-15934-1: SYSTEM AND METHOD FOR DETERMINING PHASE...

78 FR 18354 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-03-26

... the viral genome without inactivating the virus. Competitive Advantages: Most of the HEV vaccines... photoresist masks to make feature sizes below 20nm. Competitive Advantages: Improved ultrafine imaging... licensing in the U.S. in accordance with 35 U.S.C. 207 to achieve expeditious commercialization of results...

77 FR 67381 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-11-09

... viral infections, cancer stem cells, and genetically related diseases Research tool to study cancer or... biological fluids by fine-tuning chemical stability through substituting the DNA strands with chemical...

78 FR 13354 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-02-27

... such as chronic lymphocytic leukemia (CLL), hairy cell leukemia (HCL) and pediatric acute lymphoblastic... only on mature cells allows the avoidance of stem cell elimination during treatment Development Stage... cells which are the primary cause of cancer-related mortality. Vaccine can eliminate cancer stem cells...

77 FR 43601 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-07-25

... formulated for oral administration. Development Stage: Pre-clinical. In vitro data available. In vivo data... from simple expression vectors and without the production of infectious virus in eggs, and will.... Vaccine stimulated broadly neutralizing antibodies against the highly conserved epitope on the HA stem...

78 FR 9399 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-02-08

... Advantages Low cost production Lower cost vaccine Oral vaccine--no needles required Temperature-stable... limitations. This vaccine requires six injectable doses over 18 months to stimulate protective immunity...-characterized. Simple manufacturing process. Potential low-cost vaccine. Oral vaccine--avoids needles and can be...

77 FR 18831 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-03-28

... Technology: Inflammatory processes associated with the over-production of tumor necrosis-alpha (TNF-[alpha... treat insulin resistance. Insulin resistance is associated with reduced gene expression and production... and at low levels in normal melanocytes. MART-1 is a melanocyte differentiation antigen found on the...

78 FR 26791 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-05-08

... different characterization and differentiation assays. Competitive Advantages: These cells can serve as... production of B19V VP1 and VP2 capsid proteins. Co-expression of the two proteins produce empty virus-like...

75 FR 15711 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-30

.... Development of assisted reproduction technologies. Studies of early embryonic development. Development Status..., W Gong, P Proost, J Van Damme, WJ Murphy, and JM Wang. Bacterial lipopolysaccharide selectively up...

77 FR 54933 - Government-Owned Inventions, Available for Licensing

Science.gov (United States)

2012-09-06

... Gameplay Combining Different Means of Control; NASA Case No.: LAR-18016-1: Wireless Temperature Sensor....: LAR-17958-1: Wireless Open-Circuit In-Plane Strain and Displacement Sensor Requiring No Electrical... for Determining Relative Motion Between Two Bodies; NASA Case No.: LAR-17877-1: Autonomous Slat-Cove...

76 FR 47217 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-08-04

... filtration barrier. Podocyte damage and loss contribute to the initiation of glomerular diseases. Cyclin... markers. Furthermore, confluent CDK4-podocyte cultures show higher levels of gene expression for multiple podocyte differentiation genes compared with subconfluent or lower density culture. Development Stage...

77 FR 24497 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-04-24

... of federally-funded research and development. Foreign patent applications are filed on selected... of the patent applications. Small-Molecule Modulators of Lipid Storage for Treatment of Obesity, Atherosclerosis, Metabolic Syndrome and Lipid Storage Diseases Description of Technology: Lipid droplets are key...

78 FR 6120 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-01-29

... of federally-funded research and development. Foreign patent applications are filed on selected... development. Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):114-20. [PMID 21810478]. 3. Cao D, et al...-435- 5020; [email protected] . Collaborative Research Opportunity: The National Center for Advancing...

75 FR 81625 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-12-28

... of Federally-funded research and development. Foreign patent applications are filed on selected... of inflammation and improves blood vessel relaxation, lipid cholesterol profiles, and [email protected] . Collaborative Research Opportunity: The NIH Chemical Genomics Center (NCGC) is seeking...

78 FR 63229 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-10-23

... extend market coverage for companies and may also be available for licensing. FOR FURTHER INFORMATION... novel strategy to structurally modify CB1 inverse agonists with the goals of (1) limiting their brain... whose primary metabolite directly targets enzymes involved in inflammatory and fibrotic processes...

75 FR 41501 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-07-16

... manual processing. Proposed designs for instrumentation and automation. Inventors: David W. Dorward... transport, resulting in a cellular phenotype similar to that observed in the lysosomal storage disease...

75 FR 31791 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-06-04

... response in many melanoma tumors so that researchers can better understand how to boost immunogenicity... phenotypic analysis of the 888-mel cell line in order to better understand the nature of tumor cells that... learning and memory. The products are a transthyretin and other blood brain barrier impermeable proteins...

75 FR 21638 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-04-26

... been shown to play a role in bone morphogenesis, cardiovascular tissue generation, immune regulation... tissue generation. Means of studying the role of SMAD7 in immune regulation. Inventors: Marilyn Diaz (NIEHS). Related Publication: Dong C, Zhu S, Wang T, Yoon W, Li Z, Alvarez RJ, Dijke P, White B, Wigley...

75 FR 51823 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-08-23

... thicker skin on the palms and soles is regulated by underlying fibroblasts in those areas, specifically via a secreted factor (DKK1) that modulates Wnt signaling. Now, using microarray analysis to compare... and in an artificial skin model and regulates their growth, suggesting it is one of the major factors...

78 FR 46356 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-07-31

... disorders. Modafinil has attracted attention for the treatment of cognitive dysfunction in disorders such as attention-deficit/hyperactivity disorder (ADHD) as well as cocaine and methamphetamine dependence. However...) Therapeutic agent for attention/cognitive disorders (such as ADHD) Therapeutic agent for sleep disorders...

75 FR 32184 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-06-07

... spectrum of inherited diseases, with symptoms that can range from mild to very severe. Accumulated..., multiple sclerosis, chronic liver disease, and refractory celiac syndrome including that disease associated... sclerosis, celiac disease, and psoriasis as well as those with disorders associated with the retrovirus...

75 FR 4573 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-01-28

... differentiation. Inventors: Jinfang Zhu and William E. Paul (NIAID). Related Publication: J Zhu, TS Davidson, G Wei, D Jankovic, K Cui, DE Schones, L Guo, K Zhao, EM Shevach, WE Paul. Down-regulation of Gfi- 1... Standley, Ph.D.; 301-435-4074; [email protected] . Dated: January 21, 2010. Richard U. Rodriguez, Director...

75 FR 23272 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-05-03

... deep into the skin, causes more long-term effects such as wrinkles, skin aging and skin cancer... cellular structures. Tracking tissue during various physiological perturbations and observation of dynamic physiological processes. Physiological perturbations include metabolic substrates, drug delivery and anoxia...

75 FR 52756 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-08-27

... optical sectioning and imaging of biological samples. Development Status: Proof of concept has been... collaborative research to further develop improved hardware in terms of higher gradient & sweep frequencies and...

77 FR 21573 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-04-10

... Capillary Arrays for Calibration, Validation, and Quality Assurance of Quantitative Measurements from... reliable means for instrument calibration and data measurement validation of various MRI scanning... radiofrequency pulse. Competitive Advantages Allows sufficient quality assurance and instrument calibration not...

78 FR 29387 - Government-Owned Inventions, Available for Licensing

Science.gov (United States)

2013-05-20

... Heat Shield Having Edgewise Strips of Ablative Material; NASA Case No.: LAR-18166-1: Reactive... Case No.: LAR-18179-1: Processing Device for High-Speed Execution of an xRISC Computer Program. Sumara...

78 FR 69700 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-11-20

... receptor Improved bioavailability Development Stage: Early-stage. Inventors: Amy H. Newman, Ashwini Banala...: Early-stage Pre-clinical In vitro data available Inventors: Stephen M. Feinstone, Hongying Duan, Pei... recognition profiles. Vaccine. 2011 Dec 9;30(1):69-77. [PMID 22041300] 2. Duan H, et al. Amino acid residue...

76 FR 36549 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-06-22

... measured information in real-time. Applications: Transarterial chemoembolization Drug eluting bead Intravenous drug delivery Drug distribution monitoring Real-time imaging Inventors: Matthew Dreher, Elliot... a potential contribution of normal LRRK2 protein to the etiology of sporadic PD cases. Micro-RNAs...

75 FR 52758 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-08-27

... linked to chemical drugs or biological toxins thus providing cytotoxic delivery to malignant B-cells and... applications. An XMRV Tool Box: Expression Plasmids, Genes, and Proteins for All Components of the Xenotropic... International Corporation in Frederick, MD (SAIC-Frederick) have developed sixty four (64) protein expression...

76 FR 61714 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-10-05

... patent applications. Platform Technology Using Ubiquitin To Improve the Delivery and Efficacy of Cytosolic Targeted Toxins Description of Technology: Targeted toxins (TT) are hybrid protein drugs... malignant cells by inactivating cytosolic protein synthesis and inducing cell death. A major challenge in...

78 FR 3440 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-01-16

... no vaccine for malaria, and there is growing resistance to existing anti-malarial drugs. Sexual stage... Applications: Malaria vaccine, diagnostic and therapeutic. Competitive Advantages: Single protein malaria... candidate oral anthrax vaccine exists and would result in an easy-to-administer oral delivery system to...

76 FR 45839 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-08-01

... Derivatives Description of Technology: The delivery of DNA/RNA therapeutic drugs is still a major hurdle for... development of medical methods and drugs to treat diseases related to angiogenesis such as cancer, macular.... [PMID: 20725067]. 2. Gambardella L, et al. PI3K signaling through the dual GTPase- activating protein...

75 FR 36423 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-06-25

... injectable antibiotics. Interestingly, several big pharmaceutical companies have recently made strategic... al. An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. Science. 2008 Sept...

78 FR 52934 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-08-27

... low systemic toxicity. Potential Commercial Applications: Pharmaceutical compositions to selectively... (NCI), Rui Sousa (Univ. Texas Health Science Ctr) Publications: 1. Guajardo R, Sousa R. A model for the...

75 FR 32185 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-06-07

... experimental datasets in biomedical science using either gene arrays or proteomics. Omnimorph allows the user.... Applications: Development and screen for pharmaceutical drugs. Biomedical research. Development Status: The...

75 FR 4573 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-01-28

... not only inhibited the production of the mutant protein but also restored the normal, non-pathological... of vaccine-generated antibodies. J Virol. 2006 March;80(5): 2092-2099. [PubMed: 16474117]. 2. S...

75 FR 14168 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-24

... for better diagnosis of pathological conditions. The device which can readily be adapted to commercial.... at 301-435-3107 or [email protected] for more information. Dated: March 16, 2010. Richard U...

77 FR 28608 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-05-15

... Nanoparticles (NP) for HIV Treatment Description of Technology: RNA interference (RNAi) as a therapeutic agent... obtained by writing to the indicated licensing contact at the Office of Technology Transfer, National... inventors computationally and experimentally developed a new technology that utilizes two (or more) cognate...

76 FR 31616 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-06-01

... of federally-funded research and development. Foreign patent applications are filed on selected... stroke, venous thromboemblic diseases such as deep vein thrombosis (DVT), and pulmonary embolism (PE). Advantages: Due to the protection of the thrombolytic agent within the liposome structure until the time that...

76 FR 66726 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-10-27

... a Broader Cancer Patient Population Via TCR Adoptive Immunity Description of Technology: NIH scientists have developed T cell receptors (TCRs) that recognize melanoma antigen family A3 (MAGE-A3) or MAGE...-specific TCR adoptive immunotherapy. There are twelve MAGE-A superfamily antigens designated A1--A12. Their...

76 FR 10374 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-02-24

... magnetic resonance relaxation times T1 and T2 are selected that are sufficiently similar to actual patient... Sep 2010 (HHS Reference No. E-126-2010/0-US-01), entitled ``Evaluation of Breast Dynamic Contrast... Resonance Imaging Phantom for Quantitative Evaluation of Breast Imaging Techniques''. Licensing Status...

75 FR 50767 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-08-17

... MRI and CT scans; however, these scans cannot detect tumor type, i.e. glioblastoma vs. medulloblastoma...: Global cancer market is worth more than eight percent of total global pharmaceutical sales. Cancer...

75 FR 77882 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-12-14

... techniques such as MRI, CT-Scans, confocal microscopy, microCT, etc. The methods and software embodied in... offered for licensing relates to therapeutic compounds and related pharmaceutical compositions that can be...

78 FR 13352 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-02-27

... traceability for the receipt of raw materials from their source to the dispensing of finished pharmaceutical... MRI imaging Competitive Advantages: Improved resolution through composite imagery Background...

75 FR 77885 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-12-14

... techniques such as MRI, CT-Scans, confocal microscopy, microCT, etc. The methods and software embodied in... offered for licensing relates to therapeutic compounds and related pharmaceutical compositions that can be...

77 FR 8264 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-02-14

... Sialylation in Certain Muscular Atrophies, Kidney Disorders, Cancers or Poor Immune Function Description of... as inflammation, immune responses, as well as certain muscular atrophies (including hereditary... enhances successful systemic delivery, including to the central nervous system (crossing the blood-brain...

77 FR 56658 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-09-13

.... Potential Commercial Applications: Drug development for muscular disorders. Competitive Advantages... capillary-based device and system for measuring the rheological properties of solutions of synthetic and...

75 FR 75179 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-12-02

... before they can act to kill the cell. As a result, research has generally been directed to overcoming MDR... the cell long enough to exert their effects. However, compounds that inhibit ABC transporter activity... this cell line will allow researchers to decipher the biology of this gene as well as aid in the...

77 FR 11560 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-02-27

... controls without the mutation have been generated. The cell lines can be used to screen therapeutic targets... serve as useful tools to elucidate the biology driving the formation and maintenance of the PNC, and... intervention of metastasis in cancer. Use as tools to elucidate the biology of the PNC. Competitive Advantages...

77 FR 45363 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-07-31

... purposes (immunoblotting, immunoprecipitation) by those studying the biology and function of Gbeta5... plasma membrane and the cell interior, the function of the complex in the brain is largely unknown. The... studying the biology and function of RGS7. Competitive Advantages: High-titer, multi-epitope antibodies to...

76 FR 15324 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-03-21

... spontaneously immortalized renal tumor cell line that may be of great interest to industry for studying HLRCC... detection and measurement of angiogenesis (formation of new blood vessels) and metastasis (spread of cancer... (e.g. DOD). These studies could include expanding the complexity of a 3D co-culture by increasing the...

76 FR 36551 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-06-22

[email protected] . Collaborative Research Opportunity: The National Cancer Institute, Molecular Biology..., Laboratory of Molecular Biology, is seeking statements of capability or interest from parties interested in... Research, Laboratory of Molecular Biology, is seeking statements of capability or interest from parties...

75 FR 10283 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-03-05

... intraoperative sentinel lymph node mapping would improve the management of HNSCC by identifying patients for... isolated cells) of suspect lymph nodes. Applications: Use with sentinel lymph node mapping for rapid... during surgery increases effectiveness of intervention thereby reducing need for subsequent surgery...

76 FR 45838 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2011-08-01

...: Typical cancer treatments such as chemotherapy, radiation therapy and surgical resection are non-specific processes that kill healthy cells as well as diseased cells, ultimately resulting in discomfort and... overexpressed IL13-R[alpha]2, as well as other types of diseased cells (asthma, pulmonary fibrosis) which...

76 FR 59391 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Science.gov (United States)

2011-09-26

.... Patent No. 7,884,592: An Energy Efficient Method for Changing the Voltage of a DC Source to Another...: Hydrogen Generator Apparatus for an Underwater Vehicle Issued 5/10/2011//U.S. Patent No. 7,940,602...

37 CFR 1.293 - Statutory invention registration.

Science.gov (United States)

2010-07-01

... the date of publication of the statutory invention registration; (2) The required fee for filing a request for publication of a statutory invention registration as provided for in § 1.17 (n) or (o); (3) A... application. (b) Any request for publication of a statutory invention registration must include the following...

Preparedness of Government Owned Dental Clinics for the ...

African Journals Online (AJOL)

Preparedness of Government Owned Dental Clinics for the Management of Medical Emergencies: A Survey of Government Dental Clinics in Lagos. ... emergencies and the availability of emergency drugs and equipment in government dental ...

Science, technology and inventions: Children draw their own visions

Science.gov (United States)

D'Addezio, G.; Rubbia, G.; Marsili, A.

2013-12-01

Italian primary schools participated with enthusiasm to the drawing competition 'I'm a scientist too! Science and scientists from the children point of view' organized by the Laboratorio di Didattica e Divulgazione Scientifica of Istituto Nazionale di Geofisica e Vulcanologia (INGV) in Rome, Italy. The best drawings were awarded and published in the 2011 school calendar. Children were asked to realize a drawing, choosing among three suggestions: 1) How do you imagine a scientist, and how do you imagine the daily activities of a researcher? 2) What invention do you consider the most important among all those you know? 3) What would you invent? The topic 'invention' (#3) was the most successful. In fact, among the collected 1,000 drawings, 400 drawings depict scientists, nearly 150 depict scientists with their inventions, and other 350 depict inventions alone. A classification scheme was designed in order to synthetically describe this set of images and analyze it. The Draw-A-Scientist scheme, known from literature, was maintained but modified in order to characterize both inventors and inventions. A preliminary analysis about scientists reveals a persistent gender stereotype, since most of depicted persons were male and nearly half of girls draw men scientists. The image of 'mad scientist' is still present but it is mainly related to men. Women scientists are drawn by girls; they are represented as young, not crazy, usually good-looking. There are no particular differences between boys and girls in assigning research fields to scientists. Women scientists are often depicted as assistants, but when alone they are self-confident enough to give their name to an invention or to aspire for Nobel Prize. In this work we present the preliminary analysis performed on drawings containing inventions. What do girls and boys 6 to 11 years old invent? Robots, helping in housekeeping or in doing homework; rockets, space vehicles and time machines, but also fictional machines and

20 CFR 10.17 - Is a beneficiary who defrauds the Government in connection with a claim for benefits still...

Science.gov (United States)

2010-04-01

... connection with a claim for benefits, the beneficiary's entitlement to any further compensation benefits will... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Is a beneficiary who defrauds the Government in connection with a claim for benefits still entitled to those benefits? 10.17 Section 10.17...

75 FR 62412 - Notice of Proposed Information Collection: Comment Request; HUD-Owned Real Estate-Good Neighbor...

Science.gov (United States)

2010-10-08

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5380-N-36] Notice of Proposed Information Collection: Comment Request; HUD- Owned Real Estate-Good Neighbor Next Door Program AGENCY: Office... information: Title of Proposal: HUD-Owned Real Estate-Good Neighbor Next Door Program. OMB Control Number, if...

75 FR 62413 - Notice of Proposed Information Collection: Comment Request; HUD-Owned Real Estate-Dollar Home...

Science.gov (United States)

2010-10-08

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5380-N-38] Notice of Proposed Information Collection: Comment Request; HUD- Owned Real Estate--Dollar Home Sales Program AGENCY: Office of... information: Title of Proposal: HUD-Owned Real Estate--Dollar Home Sales Program. OMB Control Number, if...

76 FR 6488 - Notice of Submission of Proposed Information Collection to OMB; HUD-Owned Real Estate-Good...

Science.gov (United States)

2011-02-04

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5480-N-11] Notice of Submission of Proposed Information Collection to OMB; HUD-Owned Real Estate--Good Neighbor Next Door Program AGENCY... Lists the Following Information Title of Proposal: HUD-Owned Real Estate--Good Neighbor Next Door...

78 FR 57873 - 60-Day Notice of Proposed Information Collection: HUD-Owned Real Estate-Sales Contract and Addendums

Science.gov (United States)

2013-09-20

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5687-N-36] 60-Day Notice of Proposed Information Collection: HUD-Owned Real Estate--Sales Contract and Addendums AGENCY: Office of the Assistant... Information Collection Title of Information Collection: HUD-Owned Real Estate--Sales Contract and Addendums...

Hospital information system institutionalization processes in indonesian public, government-owned and privately owned hospitals.

Science.gov (United States)

Handayani, P W; Hidayanto, A N; Ayuningtyas, Dumilah; Budi, Indra

2016-11-01

The Hospital Information System (HIS) could help hospitals as a public entity to provide optimal health services. One of the main challenges of HIS implementation is an institutional change. Using institutional theory as the analytical lens, this study aims to explain the institutionalization of HIS as an instance of e-health initiatives in Indonesia. Furthermore, this paper aims for hospital management and researchers to improve the understanding of the social forces that influence hospital personnel's HIS acceptance within an organizational context. We use case studies from four public, government-owned hospitals and four privately owned (public and specialty) hospitals to explain the HIS institutionalization process by exploring the three concepts of institutional theory: institutional isomorphism, institutional logic, and institutional entrepreneurship. This study reveals that differences exist between public, government-owned and private hospitals with regard to the institutionalization process: public, government-owned hospitals' management is more motivated to implement HIS to comply with the regulations, while private hospitals' management views HIS as an urgent requirement that must be achieved. The study findings also reveal that various institutional isomorphism mechanisms and forms of institutional logic emerge during the process. Finally, three factors-self-efficacy, social influence, and management support-have a significant influence on the individual acceptance of HIS. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

78 FR 66040 - 30-Day Notice of Proposed Information Collection: HUD-Owned Real Estate-Sales Contract and Addendums

Science.gov (United States)

2013-11-04

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5683-N-91] 30-Day Notice of Proposed Information Collection: HUD-Owned Real Estate--Sales Contract and Addendums AGENCY: Office of the Chief... published a 30 day notice of proposed information collection entitled HUD-Owned Real Estate-Sales Contract...

77 FR 24499 - Government-Owned Inventions; Availability for Licensing: Mouse Models

Science.gov (United States)

2012-04-24

... growth hormone. Despite their similarities, they have many unique functions. Stat5a deficiency results in.... The fibroblast growth factor receptor 4 (fgfr-4) gene was inactivated by targeted disruption and... knockout mice show deficits in two hippocampus-dependent cognitive tasks, and exhibit reduced cerebral...

Post-traumatic and stress-induced osteolysis of the distal clavicle: MR imaging findings in 17 patients

International Nuclear Information System (INIS)

Puente, R. de la; Boutin, R.D.; Theodorou, D.J.; Hooper, A.; Resnick, D.; Schweitzer, M.

1999-01-01

Objective. To describe the MR imaging findings in patients with osteolysis of the distal clavicle and to compare the MR imaging appearance of clavicular osteolysis following acute injury with that related to chronic stress. Design and patients. MR imaging examinations were reviewed in 17 patients (14 men, 3 women; ages 16-55 years) with the diagnosis of post-traumatic or stress-induced osteolysis of the clavicle. A history of a single direct injury was present in seven patients and a history of weight-lifting, participation in sports, or repetitive microtrauma was present in 10 patients. Results. MR imaging showed edema in the distal clavicle in 17 patients and, of these, eight also had edema in the acromion. The edema was most evident in STIR and fat-suppressed T2-weighted pulse sequences. Other findings about the acromioclavicular (AC) joint were prominence of the joint capsule in 14, joint fluid in eight, cortical irregularity in 12, and bone fragmentation in six patients. No differences in the MR imaging features of post-traumatic and stress-induced osteolysis of the distal clavicle were observed. Conclusion. Post-traumatic and stress-induced osteolysis of the distal clavicle have similar appearances on MR imaging, the most common and conspicuous MR imaging feature being increased T2 signal intensity in the distal clavicle. (orig.)

Post-traumatic and stress-induced osteolysis of the distal clavicle: MR imaging findings in 17 patients

Energy Technology Data Exchange (ETDEWEB)

Puente, R. de la [Department of Radiology, University of California San Diego and Veterans Affairs Medical Center, San Diego, CA (United States)]|[Servicio de Radioloxia, CXH Cristal Pinor, Ourense (Spain); Boutin, R.D. [Department of Radiology, University of California San Diego and Veterans Affairs Medical Center, San Diego, CA (United States)]|[Department of Radiology, Veterans Affairs Medical Center, San Diego, CA (United States); Theodorou, D.J.; Hooper, A.; Resnick, D. [Department of Radiology, University of California San Diego and Veterans Affairs Medical Center, San Diego, CA (United States); Schweitzer, M. [Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA (United States)

1999-04-01

Objective. To describe the MR imaging findings in patients with osteolysis of the distal clavicle and to compare the MR imaging appearance of clavicular osteolysis following acute injury with that related to chronic stress. Design and patients. MR imaging examinations were reviewed in 17 patients (14 men, 3 women; ages 16-55 years) with the diagnosis of post-traumatic or stress-induced osteolysis of the clavicle. A history of a single direct injury was present in seven patients and a history of weight-lifting, participation in sports, or repetitive microtrauma was present in 10 patients. Results. MR imaging showed edema in the distal clavicle in 17 patients and, of these, eight also had edema in the acromion. The edema was most evident in STIR and fat-suppressed T2-weighted pulse sequences. Other findings about the acromioclavicular (AC) joint were prominence of the joint capsule in 14, joint fluid in eight, cortical irregularity in 12, and bone fragmentation in six patients. No differences in the MR imaging features of post-traumatic and stress-induced osteolysis of the distal clavicle were observed. Conclusion. Post-traumatic and stress-induced osteolysis of the distal clavicle have similar appearances on MR imaging, the most common and conspicuous MR imaging feature being increased T2 signal intensity in the distal clavicle. (orig.) With 5 figs., 1 tab., 19 refs.

Invention class

International Nuclear Information System (INIS)

Wang, Yeon Jung

1990-03-01

This book gives descriptions of whole conception of patent, which includes invention and human, the way to invent, ten commandments of invention, 50 well-known inventions and inventors, conception of industrial property right system, measures on industrial property right practice, measures on industrial property right invasion, the best 10 patent dispute in history, the best 10 real patent cases in history, field of patent invention, inventions and supporting system of technical development ; supporting by the patent and trademark office and the commerce-industry ministry.

Challenges of Corporate Governance in State-Owned Companies – Croatian Perspectives

Directory of Open Access Journals (Sweden)

Boris Crnković

2011-12-01

Full Text Available The term corporate governance is related to the agency problem, which is also known as the principalagent problem. In the microeconomic theory the relationship between principal and agent refers to the situation when the owner of the business and the manager running the business are not the same person. In such a case ownership and management are separated, which is a good situation for managers, who can use it to promote some of their own goals which do not necessarily have to correspond to the objectives of the business, i.e. owner of the business. The term corporate governance may also include the way in which owners of the business successfully motivate managers to act in the best interest of the owner of the business, thus maximising the company’s profit. The relationship between the principal and the agent in case of state-owned companies is two-fold (citizens – politicians and politicians – managers. Therefore corporate governance in state-owned companies faces specific challenges. From the perspective of the Republic of Croatia it is clear that progress in the privatisation process cannot be expected soon due to political and economic reasons. Therefore it is necessary to ensure an efficient system of corporate governance in state-owned companies to ensure protection of the interests of the state, i.e. the citizens in state-owned companies.

[Johan Engström. Revals Befästningsdhistoria sedd utifrån en maquett från 1682. Statens försvarshistoriska museer 2011. Skrift nr 17. ] / Ragnar Nurk, Robert Treufeld

Index Scriptorium Estoniae

Nurk, Ragnar

2014-01-01

Arvustus: Johan Engström. Revals Befästningsdhistoria sedd utifrån en maquett från 1682. Statens försvarshistoriska museer 2011. Skrift nr 17. 2011. Rootsi-aegsestest kindlustustest. Hilisema perioodi kindlustustest

To succeed with invention and patent which are my own idea

International Nuclear Information System (INIS)

Yu, Jae Bok

1999-07-01

This book introduces how to invent through various way such as successful story about the effect to invent, conception like everyone can be a inventor and this is invention. This book also explains all of process of patent such as application of patent, patent in Korea, Japan, the U.S and other countries, what is patent information, how to hunt patent, intellectual property right, priority system, international patent application is possible in Korea, other common sense on patent application, patent as a great power and questions and answers on patent.

48 CFR 1852.245-79 - Use of Government-owned property.

Science.gov (United States)

2010-10-01

...-owned facilities (real property or plant equipment), special test equipment, or special tooling... property. 1852.245-79 Section 1852.245-79 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... and Clauses 1852.245-79 Use of Government-owned property. As prescribed in 1845.106-70(i), insert the...

22 CFR 228.33 - Foreign government-owned organizations.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Foreign government-owned organizations. 228.33 Section 228.33 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND... commercial companies or other organizations (including nonprofit organizations other than public educational...

Cerebral oligodendroglioma: MR features indicating anaplastic changes

Energy Technology Data Exchange (ETDEWEB)

Choi, Choong Gon; Chang, Kee Hyun; Han, Moon Hee; Chi, Je Geun [Seoul National Univ., Seoul (Korea, Republic of); Yoon, Hyun Ki [Ulsan Univ., Seoul (Korea, Republic of)

1995-10-15

The purpose of this study is to find helpful MR findings for predicting anaplastic oligodendrogliomas. Retrospective analysis of 46 MR images and 37 CT scans was performed for 46 patients with pathologically-proven cerebral oligodendrogliomas. A neuropathologist graded the tumors as one of low-grade (n = 16), intermediate-grade (n = 12), or anaplastic oligodendroglioma (n 18). MR imaging features were retrospectively analysed with respect to histologic grading of the tumors. Contrast enhancement was observed always in anaplastic group (17/17), in a portion of intermediate-grade group (4/10) but not in low-grade group (0/4). Peritumoral edema was observed infrequently in anaplastic group (4/18) or intermediate-grade group (1/12). Cystic changes (25/46) or calcifications on CT Scans (14/37) were not related with histologic grading. Grossly identifiable hemorrhage was rare in this series (2/46). Among the various imaging features, only tumor enhancement and peritumoral edema were statistically significant for trend test ({rho} < 0.05). When considering the diagnosis of oligodendrogliomas, the presence of contrast enhancement or peritumoral edema is a helpful features suggesting anaplastic oligodendrogliomas.

77 FR 14303 - Federal Acquisition Regulation; Women-Owned Small Business (WOSB) Program

Science.gov (United States)

2012-03-09

... Economically Disadvantaged Women-Owned Small Business (EDWOSB) Concerns (APR 2012) (15 U.S.C. 637(m)).'' 4. On...: ``(25) 52.219-30, Notice of Set-Aside for Women-Owned Small Business (WOSB) Concerns Eligible Under the... Business Concerns Eligible Under the Women-Owned Small Business Program (APR 2012)'' [FR Doc. C1-2012-4475...

75 FR 33793 - Intent To Grant an Exclusive License of a U.S. Government-Owned Patent

Science.gov (United States)

2010-06-15

... DEPARTMENT OF DEFENSE Department of the Army Intent To Grant an Exclusive License of a U.S. Government-Owned Patent AGENCY: Department of the Army, DoD. ACTION: Notice. SUMMARY: In accordance with 35 U.S.C. 209(e) and 37 CFR 404.7 (a)(I)(i), announcement is made of the intent to grant a partially...

Interoperability in the e-Government Context

Science.gov (United States)

2012-01-01

TN-014 | 3 ing e- government systems focus primarily on these technical challenges [UNDP 2007a, p. 10; CS Transform 2009, p. 3]. More recently...Thailand’s government hits its own wall. Responding agencies and non- governmental groups are unable to share information vital to the rescue effort...Interoperability and Open Standards for e- Governance .” egov (Sep. 1, 2007): 17–19. [Secretary General, United Nations 2010] Secretary General, United

78 FR 17871 - Changes To Implement the Technical Corrections to the Leahy-Smith America Invents Act as to Inter...

Science.gov (United States)

2013-03-25

... Business Method Patents--Definition of Technological Invention, 77 FR 48734 (Aug. 14, 2012) (final rule... Inter Partes Review AGENCY: United States Patent and Trademark Office, Commerce. ACTION: Final rule..., United States Code (``AIA Technical Corrections Act''). Consistent with the statutory changes, this final...

Preoperative diagnosis of N-factor by MR in primary lung cancer

International Nuclear Information System (INIS)

Akata, Soichi; Amino, Saburo; Abe, Kimihiko

1993-01-01

We compared the accuracies of preoperative diagnosis of N-factor by CT and MR in 71 cases of primary lung cancer. Lymph nodes larger than 10 mm in diameter were defined as positive. As a result, CT and MR both achieved an accuracy of more than 80%. MR was inefficient in detecting calcification and showed lower spatial resolution than CT; however, MR was useful in detecting hilar lymph nodes because of the signal loss of blood vessels. MR should be used to detect the contralateral hilar lymph nodes swelling because the sensitivity in the hilus is 20% higher in MR than in CT and the information about the contralateral hilar lymph nodes is more important than ipsilateral hilar lymph nodes for operation. (author)

76 FR 42684 - Statutory Invention Registration

Science.gov (United States)

2011-07-19

... 3.00 Totals 8 10.00 There is annual (non-hour) cost burden in the way of filing fees associated with...) Filing fee $ cost burden (a) (b) (a x b) (c) Statutory Invention Registration (Requested prior to 2 $920...) respondent cost burden for this collection in the form of postage costs and filing fees will be $8,170. IV...

43 CFR 6.2 - Report of invention.

Science.gov (United States)

2010-10-01

... official working hours, the extent use was made of government facilities, equipment, funds, material or... withhold the report until the process or device is completely reduced to practice, reduction to practice... the Government and of the inventor. If an invention is reduced to practice after the invention report...

48 CFR 1852.245-70 - Contractor requests for Government-owned equipment.

Science.gov (United States)

2010-10-01

... the equipment and the reasons why contractor-owned property cannot be used, citing the applicable FAR... 1419, DOD Industrial Plant Equipment Requisition, or equivalent format, for each item requested and (ii... Government-owned equipment. 1852.245-70 Section 1852.245-70 Federal Acquisition Regulations System NATIONAL...

77 FR 73523 - HUD Acquisition Regulations (HUDAR)

Science.gov (United States)

2012-12-10

.... 48 CFR Part 2427 Government procurement, Inventions and patents. 48 CFR Part 2428 Government..., and women-owned small business; HUBZone small business; veteran-owned small business; and service... section 2426.7002. PART 2427--PATENTS, DATA, AND COPYRIGHTS 0 63. The authority citation for part 2427 is...

13 CFR 121.511 - What is the size standard for buying Government-owned petroleum?

Science.gov (United States)

2010-01-01

... buying Government-owned petroleum? 121.511 Section 121.511 Business Credit and Assistance SMALL BUSINESS... Government-owned petroleum? A concern is small for this purpose if it is primarily engaged in petroleum refining and meets the size standard for a petroleum refining business. ...

Quemaduras por frío: Revisión de 10 Años

OpenAIRE

EULUFÍ M, ALEX; PIÑEROS B, JOSÉ LUIS; CALDERÓN O, WILFREDO; CUADRA C, ÁLVARO; DANILLA E, STEFAN; LÉNIZ M, PATRICIO; ROCO M, HÉCTOR; ROA G, RICARDO; EULUFÍ M, CHRISTIAN

2006-01-01

La injuria por frío ha sido objeto de estudio desde la década de 1960, Este trabajo entrega los resultados de una revisión retrospectiva de un grupo de 10 pacientes ingresados al Hospital del Trabajador de Santiago (HTS) en un periodo de 10 años producto de accidentes laborales de distintas etiologías. Cabe señalar que solo encontramos reportes aislados de casos en la literatura revisada. Se revisaron retrospectivamente las fichas clínicas de 10 pacientes en el periodo 1993-2003. Las edades f...

75 FR 55576 - Intent To Grant Field of Use Exclusive License to U.S. Government-Owned Patents

Science.gov (United States)

2010-09-13

... DEPARTMENT OF DEFENSE Department of the Army Intent To Grant Field of Use Exclusive License to U.S. Government-Owned Patents AGENCY: Department of the Army, DoD. ACTION: Notice. SUMMARY: In accordance with 35... grant a field of use exclusive, revocable license for the field of prevention and/or therapeutic...

Do government owned banks trade market power for slack?

NARCIS (Netherlands)

Hackethal, A.; Koetter, M.; Vins, O.

2012-01-01

The 'Quiet Life Hypothesis (QLH)' posits that banks with market power have less incentives to maximize revenues and minimize cost. Especially government owned banks with a public mandate precluding profit maximization might succumb to a quiet life. We use a unified approach that simultaneously

Singapore: The Politics of Inventing National Identity

Directory of Open Access Journals (Sweden)

Stephan Ortmann

2009-01-01

Full Text Available This study wants to shed new light on the politics of Singapore’s national identity invention. Since independence in 1965, the Singaporean government has tried to generate a sense of national identity in Singapore. While at first, the priority was on pragmatic values to promote the economic development, this changed in the late 1980s when the government became concerned with the widespread materialism within the society. As an alternative, so-called Asian values sought to provide an ideological alternative and a new basis for a stronger national identity. At the same time, average Singaporeans have developed their own unique conceptions of the city-state’s national identity, which sometimes contradict the official nation-building efforts and thus constitute a subtle form of opposition. Many Singaporeans demand greater participation in the negotiation of their Singaporean identity, which demonstrates the difficulty of constructing a sustainable authoritarian civic national identity.

Advanced design of fast reactor-membrane reformer (FR-MR)

International Nuclear Information System (INIS)

Tashimo, M.; Hori, I.; Yasuda, I.; Shirasaki, Y.; Kobayashi, K.

2004-01-01

A new plant concept of nuclear-produced hydrogen is being studied using a Fast Reactor-Membrane Reformer (FR-MR). The conventional steam methane reforming (SMR) system is a three-stage process. The first stage includes the reforming, the second contains a shift reaction and the third is the separation process. The reforming process requires high temperatures of 800 ∼ 900 deg C. The shift process generates heat and is performed at around 200 deg C. The membrane reforming has only one process stage under a nonequilibrium condition by removing H2 selectively through a membrane tube. The steam reforming temperature can be decreased from 800 deg C to 550 deg C, which is a remarkable benefit offered by the non-equilibrium condition. With this new technology, the reactor type can be changed from a High Temperature Gas-cooled Reactor (HTGR) to a Fast Reactor (FR). A Fast Reactor-Membrane Reformer (FR-MR) is composed of a nuclear plant and a hydrogen plant. The nuclear plant is a sodium-cooled Fast Reactor with mixed oxide fuel and with a power of 240 MWt. The heat transport system contains two circuits, the primary circuit and the secondary circuit. The membrane reformer units are set in the secondary circuit. The heat, supplied by the sodium, can produce 200 000 Nm 3 /h by 2 units. There are two types of membranes. One is made of Pd another one (advanced) is made of, for example V, or Nb. The technology for the Pd membrane is already established in a small scale. The non-Pd type is expected to improve the performance. (author)

17 CFR 210.12-24 - Real estate owned and rental income. 1

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Real estate owned and rental... § 210.12-24 Real estate owned and rental income. 1 Part 1—Real estate owned at end of period Column A... In a separate schedule classify by states in which the real estate owned is located the total amounts...

Uncompensated care provided by for-profit, not-for-profit, and government owned hospitals.

Science.gov (United States)

Cram, Peter; Bayman, Levent; Popescu, Ioana; Vaughan-Sarrazin, Mary S; Cai, Xueya; Rosenthal, Gary E

2010-04-07

There is growing concern certain not-for-profit hospitals are not providing enough uncompensated care to justify their tax exempt status. Our objective was to compare the amount of uncompensated care provided by not-for-profit (NFP), for-profit (FP) and government owned hospitals. We used 2005 state inpatient data (SID) for 10 states to identify patients hospitalized for three common conditions: acute myocardial infarction (AMI), coronary artery bypass grafting (CABG), or childbirth. Uncompensated care was measured as the proportion of each hospital's total admissions for each condition that were classified as being uninsured. Hospitals were categorized as NFP, FP, or government owned based upon data obtained from the American Hospital Association. We used bivariate methods to compare the proportion of uninsured patients admitted to NFP, FP and government hospitals for each diagnosis. We then used generalized linear mixed models to compare the percentage of uninsured in each category of hospital after adjusting for the socioeconomic status of the markets each hospital served. Our cohort consisted of 188,117 patients (1,054 hospitals) hospitalized for AMI, 82,261 patients (245 hospitals) for CABG, and 1,091,220 patients for childbirth (793 hospitals). The percentage of admissions classified as uninsured was lower in NFP hospitals than in FP or government hospitals for AMI (4.6% NFP; 6.0% FP; 9.5% government; P < .001), CABG (2.6% NFP; 3.3% FP; 7.0% government; P < .001), and childbirth (3.1% NFP; 4.2% FP; 11.8% government; P < .001). In adjusted analyses, the mean percentage of AMI patients classified as uninsured was similar in NFP and FP hospitals (4.4% vs. 4.3%; P = 0.71), and higher for government hospitals (6.0%; P < .001 for NFP vs. government). Likewise, results demonstrated similar proportions of uninsured patients in NFP and FP hospitals and higher levels of uninsured in government hospitals for both CABG and childbirth. For the three conditions studied NFP

75 FR 60436 - Intent To Grant an Exclusive Field of Use License of U.S. Government-Owned Patents

Science.gov (United States)

2010-09-30

... DEPARTMENT OF DEFENSE Department of the Army Intent To Grant an Exclusive Field of Use License of U.S. Government-Owned Patents AGENCY: Department of the Army, DoD. ACTION: Notice. SUMMARY: In... of the intent to grant a field of use exclusive, revocable license for the field of vaccination of...

75 FR 27318 - Notice of Intent To Grant an Exclusive License; FIXMO U.S. INC.

Science.gov (United States)

2010-05-14

..., license to practice the following Government-Owned invention as described in U.S. Patent Application Serial No.11/999,050 entitled: ``Method of Tamper Detection for Digital Device,'' which was allowed by... above-mentioned invention is assigned to the United States Government as represented by the National...

Investigations of neutron-rich nuclei at the dripline through their analogue states : The cases of $^{10}$Li - $^{10}$Be (T=2) and $^{17}$C - $^{17}$N (T=5/2)

CERN Multimedia

2002-01-01

We propose to study the elastic resonance scattering reactions $^{9}$Li+p and $^{16}$C+p to investigate the energies, spins and parities of the lowest T=2 states in $^{10}$Be and the T=5/2 states in $^{17}$N. These are analogue states of the ground states and first excited states in $^{10}$Li and $^{17}$C.

75 FR 50751 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Science.gov (United States)

2010-08-17

... CFR part 404. Applications will be evaluated utilizing the following criteria: (1) Ability to... CONTACT: Dr. Charles Schlagel, Director, Office of Technology Transfer, Naval Medical Research Center, 503 Robert Grant Ave., Silver Spring, MD 20910-7500, telephone 301-319-7428 or e-mail at: charles.schlagel...

75 FR 17394 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Science.gov (United States)

2010-04-06

... CFR part 404. Applications will be evaluated utilizing the following criteria: (1) Ability to... Jean Miller, Edward Unsworth, William Hook, Thomas Walsh, Karen Gray, and Charles Macri; 12/634,119... CONTACT: Dr. Charles Schlagel, Director, Office of Technology Transfer, Naval Medical Research Center, 503...

75 FR 17396 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Science.gov (United States)

2010-04-06

... diagnostics and therapeutics for scrub typhus and HIV infections'', Inventors: Wei Mei Ching, Chien Chung Chao... orientia tsutsugamushi to be used as a vaccine component against scrub typhus'', Inventors: Wei Mei Ching..., ``Recombinant antigens for diagnosis and prevention of murine typhus'', Inventor: Wei Mei Ching, issued June 9...

75 FR 17395 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Science.gov (United States)

2010-04-06

... low power wired and wireless command, control and communication'' filed on November 24, 2008; U.S... Application Ser. No. 12/383,086 entitled ``System and method for controlling the power output of an internal... a DC source to another voltage in order to supply a load that requires a different voltage'' filed...

76 FR 37796 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Science.gov (United States)

2011-06-28

... Aircraft Division, Business and Partnership Office, Office of Research and Technology Applications... October 26, 2010 U.S. Patent Application No. 7,839,304 B2: Method and System for Alerting Aircrew to... Application No. 12/868,772: Colorimetric Method for Detection of Biodiesel in Fuel, Navy Case No. PAX37, filed...

76 FR 76743 - Government-Owned Inventions; Licensing and Collaborative Research Opportunity: Chemotoxins for...

Science.gov (United States)

2011-12-08

... extend market coverage for companies and may also be available for licensing. FOR FURTHER INFORMATION... antigen delivery strategy. The strategy uses formulations composed of chemokines fused to toxic moieties... used to cause inflammation to specifically target immune cells to increase immunogenicity for malignant...

78 FR 17187 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Science.gov (United States)

2013-03-20

... PAX80: JSF Engine actuator installation/remover tool, filed January 13, 2012//U.S. Patent Application... for data and inventor interviews should be directed to Naval Air Warfare Center Aircraft Division... FURTHER INFORMATION CONTACT: Naval Air Warfare Center Aircraft Division, Technology Transfer Office, 22473...

Human fascioliasis: MR imaging findings of hepatic lesions

International Nuclear Information System (INIS)

Cevikol, Can; Karaali, Kamil; Senol, Utku; Kabaalioglu, Adnan; Apaydin, Ali; Lueleci, Ersin; Saba, Rabin

2003-01-01

Our objective was to describe MR imaging findings of liver lesions in human fascioliasis. The MR imaging of the liver was performed in 29 patients with fascioliasis. Seventeen patients were women and 12 were men, with a mean age of 47.5 years (age range 17-75 years). Hepatic lesions were grouped into five types based on their signal characteristics. Three patients had normal imaging findings. One or more lesions were observed in the other 26 patients. The lesion types and the frequency of appearances were as follows: hyperintensity of the liver capsule on T2-weighted images (n=16, 55.2%); ill-defined slightly hyperintense areas on T2-weighted images (n=18, 62.1%); lesions which were hypointense on T1-weighted and hyperintense on T2-weighted images (n=10, 34.5%); hypointense on T1-weighted images and centrally hypo- or hyperintense, surrounded by peripherally less hyperintense area on T2-weighted images (n=4, 13.8%); and hypointense foci or ill-defined hypointense areas on T1- and T2-weighted images (n=10, 34.5%). We describe the MR imaging features of the disease. Our findings may help the differential diagnosis in which fascioliasis should be added to the list. (orig.)

Revisit the landscape of protonated water clusters H+(H2O)n with n = 10-17: An ab initio global search

Science.gov (United States)

Shi, Ruili; Li, Keyao; Su, Yan; Tang, Lingli; Huang, Xiaoming; Sai, Linwei; Zhao, Jijun

2018-05-01

Using a genetic algorithm incorporated with density functional theory, we explore the ground state structures of protonated water clusters H+(H2O)n with n = 10-17. Then we re-optimize the isomers at B97-D/aug-cc-pVDZ level of theory. The extra proton connects with a H2O molecule to form a H3O+ ion in all H+(H2O)10-17 clusters. The lowest-energy structures adopt a monocage form at n = 10-16 and core-shell structure at n = 17 based on the MP2/aug-cc-pVTZ//B97-D/aug-cc-pVDZ+ZPE single-point-energy calculation. Using second-order vibrational perturbation theory, we further calculate the infrared spectra with anharmonic correction for the ground state structures of H+(H2O)10-17 clusters at the PBE0/aug-cc-pVDZ level. The anharmonic correction to the spectra is crucial since it reproduces the experimental results quite well. The extra proton weakens the O-H bond strength in the H3O+ ion since the Wiberg bond order of the O-H bond in the H3O+ ion is smaller than that in H2O molecules, which causes a red shift of the O-H stretching mode in the H3O+ ion.

MR findings of brainstem injury

Energy Technology Data Exchange (ETDEWEB)

Park, Man Soo; Hwang, Woo Cheol; Park, Choong Ki [Hallym University College of Medicine, Seoul (Korea, Republic of); Suh, Dae Chul [University of Ulsan College of Medicine, Seoul (Korea, Republic of); Kim, Sang Joon [Dankook University of College of Medicine, Cheonan (Korea, Republic of)

1995-02-15

To analyze the characteristics of traumatic brainstem injury by CT and MR. CT and MR studies of 10 patients with traumatic brainstem lesion in MR were retrospectively reviewed, particularly attended to location, signal intensity and associated lesions. CT failed to depict 8 of 10 brainstem lesions. All lesions were detected in MR images with T2-weighted images showing higher detection rate (n = 10) (100%) than T1-weighted images (n = 3) (30%) or CT (n = 2) (20%). The brainstem lesions located in the dorsolateral aspects of the rostral brainstem (mid brain and upper pons) in 7 (70%) cases, in ventral aspects of rostral brain in 2 (20%) cases and in median portion of pons in 1 (10%) case. Corpus callosal (n = 5), lobar white matter (n = 5) diffuse axonal injury, and 2 hemorrhagic lesions in basal ganglia were the associated findings. MR imaging is more helpful than CT in the detection of brainstem injury, especially T2 weighted images. Primary brainstem lesions were typically located in the dorsolateral aspect of rostral brainstem (midbrain and upper pons). Corpus callosum and white matter lesions were frequently associated.

MR Imaging in symptomatic osteochondromas

Energy Technology Data Exchange (ETDEWEB)

Kim, Soo Young; Kim, Jee Young; Kim, Sang Heum; Chun, Kyung Ah; Park, Young Ha [Catholic University of Korea, Seoul (Korea, Republic of)

1998-06-01

The purpose of this study is to assess the MR findings of symptomatic osteochondromas. We evaluated 31 patients who between July, 1994 and May, 1997 underwent MR imaging for symptomatic osteochondroma. Fourteen were males and 17 were females, and their ages ranged from 8 to 49 (mean, 23) years. Using T1WI, T2WI and gadolinium-DTPA-enhanced T1WI, images were analysed according to signal intensity in the osseous component of the osteochondroma, thickness of the cartilage cap, and associated change in surrounding soft tissue. Clinical manifestation included a palpable mass or tendency to grow (n=22) and pain on movement (n=9). Complications were of three types : that which followed change in the osseous component of the tumor, associated change in surrounding soft tissue, and malignant transformation. In the osseous component, bone marrow edema or contusion was seen in 21 cases (67.7%), and in two (65%), fracture was observed. In surrounding soft tissue, muscle impingement was seen in 21 cases (67.7%), bursitis was in 7 cases (22.6 %), tenosynovitis in seven (22.6 %), and vascular compression in five (16.1 %). In three cases (9.7%), transformation to chondrosarcoma had occurred; two of these were derived from osteochondromatosis and one from a single osteochondroma. The thickness of the cartilage cap was as follow : < 5 mm (n=16), 5-10 mm (n=12), and > 10 mm (n=3). In patients with symptomatic osteochondroma, MR imaging is useful for detecting both complications and malignant transformation. (author). 21 refs., 1 tab., 6 figs.

Corporate governance of the state-owned enterprises in an emerging country: Risk management and related issues

Directory of Open Access Journals (Sweden)

Noluthando Shirley Matsiliza

2017-07-01

Full Text Available This article assesses the extent to which state owned enterprises (SOE have complied with corporate governance codes, as recommended by King III in South Africa. Corporate governance in the post-apartheid era has changed irrevocably. The development path which is the agenda to transform state owned enterprises has been a trial and error (trend in South Africa. This paper argues that the South African State Owned Enterprises (SOEs have applied the King III principles of corporate governance, while grappling with structural changes that impact in their practice regarding their organisational performance on risk and corporate governance. Along with regulatory measures on corporate governance, the SOEs are looking at strategies to translate the concept of corporate governance into practical solutions that involve stakeholders and government support. Using a qualitative approach, this theoretical paper employed document analysis for data collection and analysis. This paper calls for more risk intelligent management of agencies so that future opportunities and threats are recognized and addressed promptly and effectively. The value of this paper is based on its contribution to the existing knowledge area on corporate governance and leadership

Perceptions of the Invention Disclosure Process at a Federal Laboratory after the America Invents Act of 2011

Science.gov (United States)

Rice-Moore, Sharla V.

The America Invents Act of 2011 reformed the patent process in the United States. This study focused on the effect of one provision which allows the first inventor to file the application of patent to become the owner of the intellectual property. Prior to this, the Patent and Trademark Act of 1980 allowed small businesses, universities, and non-profit institutions to pursue ownership of intellectual property developed from federally funded research. The new regulations could influence government employees' disclosure of invention and new technology. There is limited research on the disclosure of technology process for government employees. This study examined 1,389 invention disclosure forms from March 2009 to March 2015 during three phases of the law: before it was signed, before the implementation of the first inventor to file provision in 2013, and after full enactment. The reported State of Development showed significant changes prior to implementation for large companies. The findings reveal disclosures were filed at an earlier stage of development, but no change was noted in the significance of the technology. A survey was also distributed using the framework of Organizational Justice theory. The results showed the disclosure reporting process was fair and unbiased. The research supports the efforts of management to keep employees informed about the disclosure process and the importance of technology transfer of government developed innovation. Key words: America Invents Act, Organizational Justice, patent process.

MR investigation of recurrent cholesteatomas

International Nuclear Information System (INIS)

Doyon, D.; Chan, K.Y.; Attia, M.; Halimi, P.; Sigal, R.; Bobin, S.; Sterkers, J.M.

1989-01-01

Nine cases of recurrent petrous cholesteatomas have been studied by a 1.5 T MR unit. Gadolinium was injected in 1 case. In all cases, comparison between MR, CT and clinical findings were made. MR allows for accurate topographic study and assessment of cholesteatomas extension, in particular in the posterior fossa and skull base. Relationships with the internal carotid artery and the jugular vein are clearly depicted [fr

17 CFR 240.14d-10 - Equal treatment of security holders.

Science.gov (United States)

2010-04-01

...: (1) Affect dissemination under Rule 14d-4 (§ 240.14d-4); or (2) Prohibit a bidder from making a... protection of investors. [51 FR 25882, July 17, 1986, as amended at 71 FR 65408, Nov. 8, 2006] ...

Teaching Case: Initial Public Offering and Implementation of a Corporate Governance System in a Family Business

Directory of Open Access Journals (Sweden)

Isaac Gezer Silva de Oliveira

2016-01-01

Full Text Available Prime Hospitality Group (PHG is a family-owned company, which was founded 17 years ago by Mr. Milton Albuquerque, with hotels and resorts scattered in different regions of Brazil. Recently, the company decided to go public in BM&FBOVESPA. Conducting an IPO, however, requires many changes in the company’s structure. These changes generate costs and change the view of family members and different stakeholders involved in the process. This case proposes an assessment of the impact caused by the implementation of a corporate governance mechanism after the completion of an IPO of a family-run company.

Case-mix and quality indicators in Chinese elder care homes: are there differences between government-owned and private-sector facilities?

Science.gov (United States)

Liu, Chang; Feng, Zhanlian; Mor, Vincent

2014-02-01

To assess the association between ownership of Chinese elder care facilities and their performance quality and to compare the case-mix profile of residents and facility characteristics in government-owned and private-sector homes. Cross-sectional study. Census of elder care homes surveyed in Nanjing (2009) and Tianjin (2010). Elder care facilities located in urban Nanjing (n = 140, 95% of all) and urban Tianjin (n = 157, 97% of all). A summary case-mix index based on activity of daily living (ADL) limitations and cognitive impairment was created to measure levels of care needs of residents in each facility. Structure, process, and outcome measures were selected to assess facility-level quality of care. A structural quality measure, understaffing relative to resident levels of care needs, which indicates potentially inadequate staffing given resident case-mix, was also developed. Government-owned homes had significantly higher occupancy rates, presumably reflecting popular demand for publicly subsidized beds, but served residents who, on average, have fewer ADL and cognitive functioning limitations than those in private-sector facilities. Across a range of structure, process, and outcome measures of quality, there is no clear evidence suggesting advantages or disadvantages of either ownership type, although when staffing-to-resident ratio is gauged relative to resident case-mix, private-sector facilities were more likely to be understaffed than government-owned facilities. In Nanjing and Tianjin, private-sector homes were more likely to be understaffed, although their residents were sicker and frailer on average than those in government facilities. It is likely that the case-mix differences are the result of selective admission policies that favor healthier residents in government facilities than in private-sector homes. © 2014, Copyright the Authors Journal compilation © 2014, The American Geriatrics Society.

A Cost Simulation Tool for Estimating the Cost of Operating Government Owned and Operated Ships

Science.gov (United States)

1994-09-01

Horngren , C.T., Foster, G., Datar, S.M., Cost Accounting : A Management Emphasis, Prentice-Hall, Englewood Cliffs, NJ, 1994 IBM Corporation, A Graphical...4. TITLE AND SUBTITLE A COST SIMULATION TOOL FOR 5. FUNDING NUMBERS ESTIMATING THE COST OF OPERATING GOVERNMENT OWNED AND OPERATED SHIPS 6. AUTHOR( S ...normally does not present a problem to the accounting department. The final category, the cost of operating the government owned and operated ships is

How Hybridity has Evolved in the Governance of State-owned Enterprises

DEFF Research Database (Denmark)

Tolstrup Christensen, Lene

2017-01-01

This paper focuses on the evolution of the governance of state-owned enterprises (SOEs) in passenger rail services. Two opposite cases are presented: one from Sweden and the other from Denmark. Using institutional change theory, the paper shows how the SOEs' hybrid character changed over time. Th...

75 FR 54330 - Intent To Grant an Exclusive Field of Use License of a U.S. Government-Owned Patent Application

Science.gov (United States)

2010-09-07

... DEPARTMENT OF DEFENSE Department of the Army Intent To Grant an Exclusive Field of Use License of a U.S. Government-Owned Patent Application AGENCY: Department of the Army, DoD. ACTION: Notice... intent to grant an exclusive, revocable license for the field of use in the research reagent market to...

75 FR 39668 - Intent To Grant a Field of Use Exclusive License of a U.S. Government-Owned Patent Application

Science.gov (United States)

2010-07-12

... DEPARTMENT OF DEFENSE Department of the Army Intent To Grant a Field of Use Exclusive License of a U.S. Government-Owned Patent Application AGENCY: Department of the Army, DoD. ACTION: Notice... intent to grant a field of use exclusive, revocable license for the field of shigella vaccine development...

22 CFR 228.54 - Suppliers of services-foreign government-owned organizations.

Science.gov (United States)

2010-04-01

... organizations. 228.54 Section 228.54 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE... interested in competing for the contract. (c) Services are not available from any other source. (d) Foreign... might be placed or any conflict of interest that might arise by permitting a foreign government-owned...

10 CFR 455.141 - Grant awards for units of local government, public care institutions, and coordinating agencies.

Science.gov (United States)

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Grant awards for units of local government, public care... CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND HOSPITALS AND BUILDINGS OWNED BY UNITS OF LOCAL GOVERNMENT AND PUBLIC CARE INSTITUTIONS Grant Awards § 455.141 Grant awards for units of local government, public care...

76 FR 66728 - Government-Owned Inventions; Licensing and Collaborative Research Opportunity for PANVAC-Cancer...

Science.gov (United States)

2011-10-27

... identification of molecular targets associated with cancer, the focus of drug development has shifted from... Immunology and Biology, Center for Cancer Research, NCI. The CRADA partner will (a) generate and characterize...; Licensing and Collaborative Research Opportunity for PANVAC--Cancer Vaccine for the Prevention and Treatment...

Dynamic MR-mammography in invasive lobular breast cancer; Dynamische MR-Mammographie beim invasiv lobulaeren Mammakarzinom bei 1,0 T

Energy Technology Data Exchange (ETDEWEB)

Sittek, H.; Perlet, C.; Kessler, M.; Reiser, M. [Institut fuer Radiologische Diagnostik, Klinikum Grossenhadern, Ludwig-Maximilians-Univ., Muenchen (Germany); Untch, M. [Klinik und Poliklinik fuer Frauenheilkunde und Geburtshilfe, Klinikum Grossenhadern, Ludwig-Maximilians-Univ., Muenchen (Germany)

1998-12-31

Material and Methods: We carried out 1505 MR mammographoes in 1357 patients. Biopsy was indicated in 413 cases. Among the malignancies, 23/214 (10%) were ILC. MR-M was performed with a 1.0 T whole body MRI system with a dynamic FLASH-3D sequence. Relative signal enhancement within lesions detected and morphologic pattern of contrast enhancement (mep) were determined. Three types of mep were distinguished: type 1 without contrast enhancement, type 2 with focal contrast enhancement, and type 3 with diffuse contrast enhancement of the glandular body. Results: Within MR-M alone, 19/23 (82.6%) of ILC were detected due to a mep type 2. Four ILC were false negative on MR-M (2 cases show mep type 1 or mep type 3). The sensitivity of Mx alone was 86.9% (20/23). When both Mx and MR-M were combined, all 23 ILC were detected. The addition of MR-M to Mx may increase sensitivity to about 100% in the detection of ILC. (orig.) [Deutsch] Material und Methode: Im Zeitraum 05/1993 bis 06/1996 fuehrten wir bei 1357 Patientinnen 1505 MR-Mammographien durch. In 413 Faellen wurde eine Probeexzision indiziert. Die histologische Untersuchung ergab in 214 Faellen einen malignen Tumor. Darunter befanden sich 23 ILC. Die MR-M wurden an einem 1,0 T MRT-System (Impact, Siemens, Erlangen) mit einer dynamischen FLASH 3D Sequenz durchgefuehrt. Neben dem prozentualen Anstieg der Signalintensitaet innerhalb einer Laesion haben wir fuer die Diagnostik folgende morphologische Befundmuster (BM) unterschieden: Typ 1: Keine Aufnahme, Typ 2: Fokale Aufnahme, Typ 3: Diffuse Aufnahme des Druesenkoerpers in der MR-M. Ergebnisse: Mit der MR-M konnten 19/23 (82,6%) der ILC anhand einer fokalen Zunahme der Signalintensitaet richtig positiv erkannt werden (BM Typ 2). Vier der ILC waren in der MR-M falsch negativ. In zwei Faellen (2/23) war keine Zunahme der Signalintensitaet zu verzeichnen (BM Typ 1). In zwei weiteren Faellen (2/23) maskierte eine diffuse Signalintensitaetszunahme des Druesenkoerpers (BM Typ 3

45 CFR 650.19 - Electronic invention handling.

Science.gov (United States)

2010-10-01

... Report or a Final Invention Statement and Certification. (b) Questions on use of iEdison and requests for... 45 Public Welfare 3 2010-10-01 2010-10-01 false Electronic invention handling. 650.19 Section 650... PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information...

Invention note and patent note

International Nuclear Information System (INIS)

Chang, Sung Su

1997-09-01

This book deals with origin of invention and term related patent and invention, making idea, brain storming, 10 laws of invention skill, attitude of inventors, invention order, making good inventions, patent system, preparation of application, procedure and method of patent, management of patent, patent and trademark office, patent lawyer, copyright, new intellectual property right, industrial property right, trademark, invasion of industrial property right, patent, Judgment, preparation of items, application of industrial property right and effect of inventor and related people.

Background story of the invention of efficient blue InGaN light emitting diodes

Energy Technology Data Exchange (ETDEWEB)

Nakamura, Shuji [University of California, Santa Barbara, CA (United States)

2015-06-15

Shuji Nakamura discovered p-type doping in Gallium Nitride (GaN) and developed blue, green, and white InGaN based light emitting diodes (LEDs) and blue laser diodes (LDs). His inventions made possible energy efficient, solid-state lighting systems and enabled the next generation of optical storage. Together with Isamu Akasaki and Hiroshi Amano, he is one of the three recipients of the 2014 Nobel Prize in Physics. In his Nobel lecture, Shuji Nakamura gives an overview of this research and the story of his inventions. (copyright 2015 by WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

MR appearance of cartilage defects of the knee: preliminary results of a spiral CT arthrography-guided analysis

International Nuclear Information System (INIS)

Berg, B.C. vande; Lecouvet, F.E.; Maldague, B.; Malghem, J.

2004-01-01

The aim of this study was to determine signal intensity patterns of cartilage defects at MR imaging. The MR imaging (3-mm-thick fat-suppressed intermediate-weighted fast spin-echo images) was obtained in 31 knees (21 male and 10 female patients; mean age 45.5 years) blindly selected from a series of 252 consecutive knees investigated by dual-detector spiral CT arthrography. Two radiologists determined in consensus the MR signal intensity of the cartilage areas where cartilage defects had been demonstrated on the corresponding reformatted CT arthrographic images. There were 83 cartilage defects at spiral CT arthrography. In 52 (63%) lesion areas, the MR signal intensity was higher than that of adjacent normal cartilage with signal intensity equivalent to (n=31) or lower than (n=21) that of articular fluid. The MR signal intensity was equivalent to that of adjacent normal cartilage in 17 (20%) lesion areas and lower than that of adjacent cartilage in 8 (10%) lesion areas. In 6 (7%) lesion areas, mixed low and high signal intensity was observed. The MR signal intensity of cartilage defects demonstrated on spiral CT arthrographic images varies from low to high on fat-suppressed intermediate-weighted fast spin-echo MR images obtained with our equipment and MR parameters. (orig.)

76 FR 37376 - Sunshine Act Meeting Federal Register Citation of Previous Announcement: 76 FR 35472, June 17, 2011

Science.gov (United States)

2011-06-27

... DEPARTMENT OF JUSTICE Parole Commission Sunshine Act Meeting Federal Register Citation of Previous Announcement: 76 FR 35472, June 17, 2011 PREVIOUSLY ANNOUNCED TIME AND DATE OF THE MEETING: 10 a.m., Tuesday, June 21, 2011. CHANGES IN THE MEETING: Removal of agenda item 5: Discussion and vote on a final rule on...

Envelope composition of Salmonella typhimurium 395 MS and 395 MR10 assesses by X-ray photoelectron spectroscopy (ESCA)

International Nuclear Information System (INIS)

Magnusson, K.F.; Johansson, L.

1977-01-01

The Salmonella typhimurium 395 MS and MR10 bacteria and lipopolysaccharide (LPS) were studied by X-ray photoelectron spectroscopy with the aid of the ESCA technique for the in situ analysis of chemical elements (C, O and N) at the surface. The nitrogen peak was large in both bacteria implying the presence of protein in the very outer part of the bacterial envelope due to the surface-sensitive measurement. The nitrogen peak was larger in the MR10 than in the MS bacteria, presumably reflecting an increased exposure of proteins concomitantly with the reduction of the LPS in MR10. After corrections for background and sensitivity of detection the relative intensities of the peaks agreed appreciably well with the proposed chemical structure of the LPS, indicating that at least semiquantitative relationships between the elements were obtained. (author)

10 CFR 603.860 - Rights to inventions.

Science.gov (United States)

2010-01-01

... approved by assigned intellectual property counsel. (c) Taking past investments as an example, the... DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms Related to Other Administrative Matters Intellectual Property § 603.860 Rights to inventions. (a) The...

An experimental study of exogenous lipoid pneumonia : sequential changes in high-resolution CT and MR findings

International Nuclear Information System (INIS)

Kim, Kyeong Ah; Kang, Eun Young; Kim, Dae Hyun; Park, Sang Woo; Choi, Jeong Cheol; Kim, Ae Ree; Kim, Han Kyum; Cha, In Ho

1999-01-01

To evaluate sequential changes in high-resolution CT(HRCT) and MR findings of exogenous lipoid pneumonia in rabbits and to compare the radiologic and histopathologic findings. A single endobronchial administration of shark liver oil(0.5 or 1 ml/kg of body weight) was given to 25 rabbits. HRCT scans were obtained immediately(n=17), at 1 day(n=14), 3 days(n=10), 1 week(n=15), 2 weeks(n=10), 4 weeks(n=9), 6 weeks(n=5), 8 weeks(n=6), 10 weeks(n=4), 12 weeks(n=2), 14 weeks(n=3), and 16 weeks(n=2) after administration. Changes in distribution, extent, and attenuation were assessed on HRCT scans. MR scans were obtained immediately(n=12), at 1 day(n=9), 3 days(n=9), 1 week(n=15), 2 weeks(n=9), 4 weeks(n=11), 6 weeks(n=5), 8 weeks(n=7), 10 weeks(n=3), 14 weeks(n=3), and at 16 weeks(n=2) after administration. Changes in distribution, extent, and signal intensity were assessed on MR scans. In 16 rabbits, CT and MR findings were compared with histopatholo-gic findings obtained in the same plane. HRCT findings included consolidation with air-bronchogram, ground-glass attenuation and fat attenuation within the lesion at earlier stages(immediate-2 weeks). The extent of lesions was greatest at 1 week, and was then seen to gradually decrease on follow-up CT scans. T1-weighted MR images(T1WI) showed high or intermediate signal intensity(SI) at earlier stages and intermediate SI at later stages, while T2-weighted MR images(T2WI) showed high SI at both earlier and later stages. Histopathologic correlation showed that ground-glass attenuation and consolidation on HRCT reflected intraalveolar lipid-laden macrophages, cuboidal metaplasia of alveolar epithelial cells, and alveolar septal widening with inflammatory cell infiltration. Maximal infiltration of oil in the lung correlated closely with the peak low-attenuation seen on CT scans and the high signal intensity seen on T1WI. Shark liver oil-induced exogenous lipoid pneumonia in rabbits is reliably diagnosed by HRCT and MR during

MR Imaging in symptomatic osteochondromas

International Nuclear Information System (INIS)

Kim, Soo Young; Kim, Jee Young; Kim, Sang Heum; Chun, Kyung Ah; Park, Young Ha

1998-01-01

The purpose of this study is to assess the MR findings of symptomatic osteochondromas. We evaluated 31 patients who between July, 1994 and May, 1997 underwent MR imaging for symptomatic osteochondroma. Fourteen were males and 17 were females, and their ages ranged from 8 to 49 (mean, 23) years. Using T1WI, T2WI and gadolinium-DTPA-enhanced T1WI, images were analysed according to signal intensity in the osseous component of the osteochondroma, thickness of the cartilage cap, and associated change in surrounding soft tissue. Clinical manifestation included a palpable mass or tendency to grow (n=22) and pain on movement (n=9). Complications were of three types : that which followed change in the osseous component of the tumor, associated change in surrounding soft tissue, and malignant transformation. In the osseous component, bone marrow edema or contusion was seen in 21 cases (67.7%), and in two (65%), fracture was observed. In surrounding soft tissue, muscle impingement was seen in 21 cases (67.7%), bursitis was in 7 cases (22.6 %), tenosynovitis in seven (22.6 %), and vascular compression in five (16.1 %). In three cases (9.7%), transformation to chondrosarcoma had occurred; two of these were derived from osteochondromatosis and one from a single osteochondroma. The thickness of the cartilage cap was as follow : 10 mm (n=3). In patients with symptomatic osteochondroma, MR imaging is useful for detecting both complications and malignant transformation. (author). 21 refs., 1 tab., 6 figs

MR-imaging of anterior tibiotalar impingement syndrome: Agreement, sensitivity and specificity of MR-imaging and indirect MR-arthrography

Energy Technology Data Exchange (ETDEWEB)

Haller, Joerg [Department of Radiology, Hanusch Hospital, Heinrich Collin-Strasse 30, A-1140 Vienna (Austria); Ludwig Boltzmann Institute for Osteology, Hanusch Hospital, Heinrich Collin-Strasse 30, A-1140 Vienna (Austria); Bernt, Reinhard [Department of Radiology, Hanusch Hospital, Heinrich Collin-Strasse 30, A-1140 Vienna (Austria)]. E-mail: reinhard.bernt@wgkk.sozvers.at; Seeger, Thomas [Department of Trauma Surgery, Hanusch Hospital, Heinrich Collin-Strasse 30, A-1140 Vienna (Austria); Weissenbaeck, Alexander [Department of Trauma Surgery, Hanusch Hospital, Heinrich Collin-Strasse 30, A-1140 Vienna (Austria); Tuechler, Heinrich [Ludwig Boltzmann Institute for Hematology, Hanusch Hospital, Heinrich Collin-Strasse 30, A-1140 Vienna (Austria); Resnick, Donald [Department of Radiology, VA Medical Center, UCSD, 3350 La Jolla Village Dr, San Diego, CA 92161 (United States)

2006-06-15

Objective: To clarify the role of MR-imaging in the diagnosis of anterior ankle impingement syndromes. Materials and methods: We prospectively examined 51 consecutive patients with chronic ankle pain by MR-imaging. Arthroscopy was performed in 29 patients who previously underwent non-enhanced MR-imaging; in 11 patients, indirect MR-arthrography additionally was performed. MR-examinations were correlated with clinical findings; MR and arthroscopy scores were statistically compared, agreement was measured. Results: Arthroscopy demonstrated granulation tissue in the lateral gutter (38%) and anterior recess (31%), lesions of the anterior tibiofibular (31%) and the anterior talofibular ligament (21%) as well as intraarticular bodies (10%). Stenosing tenosynovitis and a ganglionic cyst were revealed as extraarticular causes for chronic ankle pain by MR-examination (17%). Agreement of MR-imaging and arthroscopy was fair for the anterior talofibular ligament and the anterior joint cavity (kappa 0.40). Major discrepancy was found for non-enhanced MR scans (kappa 0.49) when compared with indirect MR-arthrography (kappa 0.03) in the anterior cavity. The sensitivity for lesions of the anterior talofibular and calcaneofibular ligament and the anterior cavity (0.91-0.87) detected by MR-imaging was superior in comparison to lesions of the anterior tibiofibular ligament and anteromedial cavity (0.50-0.24). Conclusion: MR-imaging provides additional information about the mechanics of chronic ankle impingement rather than an accurate diagnosis of this clinical entity. The method is helpful in differentiating extra- from intra-articular causes of ankle impingement. Indirect MR-arthrography has little or no additional value in patients with ankle impingement syndrome.

MR-imaging of anterior tibiotalar impingement syndrome: Agreement, sensitivity and specificity of MR-imaging and indirect MR-arthrography

International Nuclear Information System (INIS)

Haller, Joerg; Bernt, Reinhard; Seeger, Thomas; Weissenbaeck, Alexander; Tuechler, Heinrich; Resnick, Donald

2006-01-01

Objective: To clarify the role of MR-imaging in the diagnosis of anterior ankle impingement syndromes. Materials and methods: We prospectively examined 51 consecutive patients with chronic ankle pain by MR-imaging. Arthroscopy was performed in 29 patients who previously underwent non-enhanced MR-imaging; in 11 patients, indirect MR-arthrography additionally was performed. MR-examinations were correlated with clinical findings; MR and arthroscopy scores were statistically compared, agreement was measured. Results: Arthroscopy demonstrated granulation tissue in the lateral gutter (38%) and anterior recess (31%), lesions of the anterior tibiofibular (31%) and the anterior talofibular ligament (21%) as well as intraarticular bodies (10%). Stenosing tenosynovitis and a ganglionic cyst were revealed as extraarticular causes for chronic ankle pain by MR-examination (17%). Agreement of MR-imaging and arthroscopy was fair for the anterior talofibular ligament and the anterior joint cavity (kappa 0.40). Major discrepancy was found for non-enhanced MR scans (kappa 0.49) when compared with indirect MR-arthrography (kappa 0.03) in the anterior cavity. The sensitivity for lesions of the anterior talofibular and calcaneofibular ligament and the anterior cavity (0.91-0.87) detected by MR-imaging was superior in comparison to lesions of the anterior tibiofibular ligament and anteromedial cavity (0.50-0.24). Conclusion: MR-imaging provides additional information about the mechanics of chronic ankle impingement rather than an accurate diagnosis of this clinical entity. The method is helpful in differentiating extra- from intra-articular causes of ankle impingement. Indirect MR-arthrography has little or no additional value in patients with ankle impingement syndrome

Study on volumetry by MR images using our own making phantoms of known volume

International Nuclear Information System (INIS)

Tsuji, Akio; Matsuo, Michimasa; Kuroda, Yasumasa; Nishiki, Shigeo; Iwaya, Kazuo; Tada, Katsunori; Matsushita, Yoko; Okayama, Yukinari

1990-01-01

The volumetry of the left atrium has been attempted with various methods including CT, ultrasonography or angiography in patients with the heart diseases. However, there are still some controversies in the results estimated because of complicated shape of the left atrium. MR imaging has also become expecting for its less invasiveness and capability of cine-mode display. To solve the basic problem, we performed experimental studies on the self-made phantoms; one for simulation volumetry and the other for examining the inhomogeneity of the magnetic field. The data analysis system consists of a personal computer (PC 9801VX, NEC) hooked into a 1.0 tesla MR unit (Magnetom M10, Siemens), and a commercially-available software for the three-dimensional reconstruction. The results included; 1) good correlation between the true phantom volume and the measured, 2) excellent reproducibility in the maneuver of tracing the contour of the phantom on CRT screen among five different persons, 3) overestimation of MR volumetry on more oblique slices likely due to partial volume phenomenon, and 4) maximum difference of localization remaining to measure several millimeters within the atrium phantom. These results suggest that the presented method can be clinically applied to the left atrial volumetry in each cardiac phase, if necessary. (author)

MR-guided percutaneous biopsy of solitary pulmonary lesions using a 1.0-T open high-field MRI scanner with respiratory gating

Energy Technology Data Exchange (ETDEWEB)

Liu, Ming; Huang, Jie; Xu, Yujun; He, Xiangmeng; Lue, Yubo; Liu, Qiang; Li, Chengli [Department of Interventional MRI, Shandong Medical Imaging Research Institute affiliated to Shandong University, Shandong Key Laboratory of Advanced Medical Imaging Technologies and Applications, Jinan, Shandong (China); Li, Lei [Qingdao Central Hospital, Department of Interventional Radiology, Qingdao, Shandong (China); Blanco Sequeiros, Roberto [Turku University Hospital, The South Western Finland Imaging Centre, Turku (Finland)

2017-04-15

To prospectively evaluate the feasibility, safety and accuracy of MR-guided percutaneous biopsy of solitary pulmonary lesions using a 1.0-T open MR scanner with respiratory gating. Sixty-five patients with 65 solitary pulmonary lesions underwent MR-guided percutaneous coaxial cutting needle biopsy using a 1.0-T open MR scanner with respiratory gating. Lesions were divided into two groups according to maximum lesion diameters: ≤2.0 cm (n = 31) and >2.0 cm (n = 34). The final diagnosis was established in surgery and subsequent histology. Diagnostic accuracy, sensitivity and specificity were compared between the groups using Fisher's exact test. Accuracy, sensitivity and specificity of MRI-guided percutaneous pulmonary biopsy in diagnosing malignancy were 96.9 %, 96.4 % and 100 %, respectively. Accuracy, sensitivity and specificity were 96.8 %, 96.3 % and 100 % for lesions 2.0 cm or smaller and 97.1 %, 96.4 % and 100 %, respectively, for lesions larger than 2.0 cm. There was no significant difference between the two groups (P > 0.05). Biopsy-induced complications encountered were pneumothorax in 12.3 % (8/65) and haemoptysis in 4.6 % (3/65). There were no serious complications. MRI-guided percutaneous biopsy using a 1.0-T open MR scanner with respiratory gating is an accurate and safe diagnostic technique in evaluation of pulmonary lesions. (orig.)

MR imaging of posttraumatic spinal ligament injury

International Nuclear Information System (INIS)

Pathria, M.N.; Emery, S.; Masaryk, T.J.; Wilber, R.G.; Bohlman, H.

1988-01-01

The accuracy of MR imaging in the detection of ligamentous injury was evaluated in 29 patients (24 male, five female) with spinal injury resulting in fractures (n=27), evidence of instability (n=11), or neurologic deficit (n=2). MR examinations were performed acutely (average, 7.5 days posttrauma) with T1- and T2-weighted imaging and were blindly evaluated. Subsequently, plain films (n=27), tomograms (n=10), and CT scans (n=22) were evaluated. Eighteen patients underwent surgery. Fourteen patients had torn ligaments as indicated by clinical and surgical findings. MR imaging demonstrated ligament damage in 13. One case imaged 40 days following trauma was not detected. No patients with intact ligaments had evidence of ligamentous damage on MR images. MR imaging demonstrated retropulsed fractures in six patients in whom the posterior longitudinal ligament was intact but displaced from the vertebra. MR imaging was more reliable than radiography and CT for detection of ligamentous injury, and T2- weighted sequences are essential in such cases

CT and MR imaging findings of sinonasal angiomatous polyps

Energy Technology Data Exchange (ETDEWEB)

Zou, Jing [Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong (China); Man, Fengyuan [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing (China); Deng, Kai [Department of Radiology, Qingdao No. 4 People' s Hospital, Qingdao, Shandong (China); Zheng, Yuanyuan [Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong (China); Hao, Dapeng, E-mail: haodp_2009@163.com [Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong (China); Xu, Wenjian, E-mail: cjr.xuwenjian@vip.163.com [Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong (China)

2014-03-15

Objective: To characterize the CT and MR imaging findings of patients with sinonasal angiomatous polyps (SAPs) and evaluate their respective clinical value in the diagnosis of SAP. Methods: CT and MR imaging findings of 15 patients with pathologically proven SAP were examined. Assessed image features included location, size, margin, attenuation, and change of the bony walls of the sinonasal cavity on CT, and signal intensity and enhancement pattern on MR. Results: On CT, the SAP was mostly isoattenuated with patches of slight hyperattenuation. Most lesions caused changes in the adjacent bone, including expansile remodeling (n = 8), defect or destruction (n = 7), and hyperostosis (n = 6). All lesions examined by MR showed heterogeneous isointense signal intensity on T1-weighted images and mixed obvious hyperintense and hypointense signal intensity with linear hypointense septum internally (n = 10), and hypointense peripheral rim on T2-weighted images (n = 10). Postcontrast MR images demonstrated areas of heterogeneous and marked enhancement with an unenhanced hypointense rim and septa (n = 7). Conclusions: CT and MR imaging have respective advantages in the diagnosis of SAP. Combined application of CT and MR examinations is necessary for patients with suspected SAP.

CT and MR imaging findings of sinonasal angiomatous polyps

International Nuclear Information System (INIS)

Zou, Jing; Man, Fengyuan; Deng, Kai; Zheng, Yuanyuan; Hao, Dapeng; Xu, Wenjian

2014-01-01

Objective: To characterize the CT and MR imaging findings of patients with sinonasal angiomatous polyps (SAPs) and evaluate their respective clinical value in the diagnosis of SAP. Methods: CT and MR imaging findings of 15 patients with pathologically proven SAP were examined. Assessed image features included location, size, margin, attenuation, and change of the bony walls of the sinonasal cavity on CT, and signal intensity and enhancement pattern on MR. Results: On CT, the SAP was mostly isoattenuated with patches of slight hyperattenuation. Most lesions caused changes in the adjacent bone, including expansile remodeling (n = 8), defect or destruction (n = 7), and hyperostosis (n = 6). All lesions examined by MR showed heterogeneous isointense signal intensity on T1-weighted images and mixed obvious hyperintense and hypointense signal intensity with linear hypointense septum internally (n = 10), and hypointense peripheral rim on T2-weighted images (n = 10). Postcontrast MR images demonstrated areas of heterogeneous and marked enhancement with an unenhanced hypointense rim and septa (n = 7). Conclusions: CT and MR imaging have respective advantages in the diagnosis of SAP. Combined application of CT and MR examinations is necessary for patients with suspected SAP

Humanisme : inventer l'avenir

Science.gov (United States)

Mayor, Federico

2014-06-01

Humanism: inventing the future - Humanity is still confronted by the scourges of poverty, hunger, violence and inequality. If we are to invent a better future, we must first understand the past, recalling the missed opportunities of 1918, 1945 and 1989, at the end of two world wars and a cold war. This article summarises the proposals put forward by the author on several occasions during his career. He expresses a forceful confidence in humankind's ability to take control of its destiny and shake off government that puts economic interest before universal human values. The twenty-first century should be the era of rebellion in cyberspace, one in which more women and young people are involved in decision making, heralding a future of freedom and happiness for all.

1 CFR 11.4 - The United States Government Manual.

Science.gov (United States)

2010-01-01

... Documents under the general direction of the Administrative Committee. The online edition of the Manual... Government Printing Office (44 U.S.C. 4101). [54 FR 9677, Mar. 7, 1989, as amended at 58 FR 64872, Dec. 10...

MR evaluation of CSF fistulae

International Nuclear Information System (INIS)

Gupta, V.; Goyal, M.; Mishra, N.; Gaikwad, S.; Sharma, A.

1997-01-01

Purpose: To evaluate the role of MR imaging in the localisation of cerebrospinal fluid (CSF) fistulae. Material and Methods: A total of 36 consecutive unselected patients with either clincally proven CSF leakage (n=26) or suspected CSF fistula (n=10) were prospectively evaluated by MR. All MR examinations included fast spin-echo T2-weighted images in the 3 orthogonal planes. Thin-section CT was performed following equivocal or negative MR examination. MR and CT findings were correlated with surgical results in 33 patients. Results: CSF fistula was visualised as a dural-bone defect with hyperintense fluid signal continuous with that in the basal cisterns on T2-weighted images. MR was positive in 26 cases, in 24 of which the fistula was confirmed surgically. In 2 patients the CSF leakage was directly demonstrated on MR. MR sensitivity of 80% compared favourably with the reported 46-81% of CT cisternography (CTC). No significant difference in MR sensitivity in detecting CSF fistula was found between active and inactive leaks. (orig.)

Functional MR imaging in the patients with complex partial seizures

International Nuclear Information System (INIS)

Chung, Jin Il; Chang, Kee Hyun; Song, In Chan; Goo, Jin Mo; Chung, Chun Kee; Lee, Sang Kun; Kim, Hong Dae; Han, Moon Hee; Kim, Sam Soo

1999-01-01

To evaluate the clinical usefulness of functional MR imaging (fMRI) for localization of the cerebral motor and sensory cortices and language center in patients with complex partial seizure. A total of 47 fMRIs were obtained in 14 patients (M:F = 9:5; age 15-50 years; 13 right handed and 1 ambidextrous) with complex partial seizure (6 temporal lobe epilepsy, 6 frontal lobe epilepsy, 1 occipitotemporal lobe epilepsy, 1 hemispheric epilepsy). Conventional MR imaging revealed no abnormality in four patients, localized cerebral atrophy in one, hippocampal sclerosis in four, and benign neoplasm in the remaining five. fMRI was performed on a 1.5 T MR scanner (GE Signa Horizon) using gradient-echo singleshot EPI. Nineteen fMRIs were obtained in eight patients who performed the language task, 16 fMRIs in ten who performed the motor task and 12 fMRIs in ten who performed the somatosensory task. The activation task consisted of three language tasks (silent picture naming , word generation from a character, categorical word generation), motor tasks (opposition of thumb and index finger for hand/dorsifexion or extension for foot), and sensory tasks (passive tactile stimulation of hand or foot using a toothbrush). The data were analyzed using z-score (p<0.05), clustering, and cross-correlation analysis based upon homemade software, IDL 5.1. The success rate for obtaining meaningful fMRI was evaluated and activated regions were assessed on the basis of each fMRI obtained during, language, motor, and somatosensory tasks. fMRI findings were compared with those of the Wada test (n = 7) for language lateralization and with invasive cortical mapping (n = 3) for the localization of eloquent cerebral cortex, especially around the central sulcus. The overall success rate of fMRI was 79 % (37/47); success rates of fMRI with language, sensory, and motor task were 89% (17/19), 83 % (10/12), and 63 % (10/16), respectively. Areas activated during language tasks (n=17) included the

Invitation to the IAEA FR17 Conference on Fast Reactors, Russia, 2017

International Nuclear Information System (INIS)

Rachkov, V.

2013-01-01

Russian Federation has a large successful experience of peaceful application of nuclear power and it is a leader in development of fast reactors that permit to create sustainable and safe base for future world nuclear power. Russian Government approved in 2010 a Federal Target Program “Nuclear power technologies of a new generation for period of 2010-2015 and with outlook to 2020” aimed at creation of new technological platform for future nuclear power based on fast reactors. State Atomic Energy Corporation “Rosatom” supports activities of the IAEA on strengthening international collaboration on fast reactors and invites IAEA to host next FR17 Conference on FRs in Russia in 2017

MR imaging of pineal cysts

International Nuclear Information System (INIS)

Ahn, Yong Sik; Yu, Hyeon; Kim, Wan Tae; Bae, Jin Woo; Moon, Hee Jung; Shin, Hyun Ja

1999-01-01

To evaluate the incidence and characteristic findings of pineal cyst incidentally detected on magnetic resonance (MR) imaging. Brain MR images obtained in 2432 patients were retrospectively reviewed to determine the incidence and MR findings of pineal cysts, which were evaluated according to their size, shape, location, signal intensity, interval change, contrast enhancement and mass effect on adjacent structures. Cysts were encountered in 107(4.4 %) of 2432 patients evaluated. their size ranged from 1 X 1 X 1 to 15 X 8 X 9 (mean, 5.97 X 3.82 X 4.82)mm. All were spherical (n=53) or oval (n=54) in shape. Their margin was smooth and they were homogeneous in nature. On T1-weighted images, the cysts were seen to be hyperintense (n=57) or isointense (n=50) to cerebrospinal fluid, but less so than brain parenchyma. T2-weighted images showed them to be isointense (n=51)or hyperintense (n=56) to cerebrospinal fluid. The cysts were centrally located in 65 cases and eccentrically in 42. Compression of the superior colliculi of the tectum was demonstrated in 17 cases (15.9 %). NO patients presented clinical symptoms or signs related to either pineal or tectal lesions. Peripheral enhancement around the cyst after Gd-DTPA injection was demonstrated in 51 cases(100 %). Follow-up examinations in 19 cases demonstrated no interval change. The incidence of pineal cysts was 4.4 %. The MR characteristics of simple pineal cysts include: (1) an oval or spherical shape, (2) a smooth outer margin and homogeneous nature, (3) isosignal or slightly high signal intensity to cerebrospinal fluid on whole pulse sequences, (4) ring enhancement after contrast injection, (5) an absence of interval change, as seen during follow up MR study. These MR appearances of pineal cysts might be helpful for differentiating them from pineal tumors

77 FR 4026 - Intent To Grant an Exclusive License of U.S. Government-Owned Invention

Science.gov (United States)

2012-01-26

... Application No. PCT/US2009/060852 entitled ``Method and Device for Detection of Bioavailable Drug... of Tennessee with its principal place of business at UT Conference Center, Suite 211, 600 Henley Street, Knoxville, TN 37996-4122. ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command...

78 FR 11164 - Intent To Grant an Exclusive License of U.S. Government-Owned Invention

Science.gov (United States)

2013-02-15

... Specificities to Protein and Lipid Epitopes,'' to Avanti Polar Lipids with its principal place of business at 700 Industrial Park Drive, Alabaster, AL 35007. ADDRESSES: Commander, U.S. Army Medical Research and... FURTHER INFORMATION CONTACT: For licensing issues, Dr. Paul Mele, Office of Research & Technology...

76 FR 34968 - Intent to Grant an Exclusive License of U.S. Government-Owned Inventions

Science.gov (United States)

2011-06-15

... (Publication Number WO 2010/042780), entitled ``Methods and Compositions for Treating Status Epilepticus and Seizures Causing Status Epilepticus'', to Biomedisyn Corporation with its principal place of business at 12...

Characterization of the March 2017 tank 10 surface sample (combination of HTF-10-17-30 AND HTF-10-17-31) and variable depth sample (combination of HTF-10-17-32 and HTF-10-17-33)

Energy Technology Data Exchange (ETDEWEB)

Reboul, S. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-07-19

Two surface samples (HTF-10-17-30 and HTF-10-17-31) and two variable depth samples (HTF-10-17-32 and HTF-10-17-33) were collected from SRS Tank 10 during March 2017 and submitted to SRNL for characterization. At SRNL, the two surface samples were combined in one container, the two variable depth samples (VDSs) were combined in another container, and then the two composite samples were each characterized by a series of physical, ionic, radiological, and elemental analysis methods. The surface sample composite was characterized primarily for Tank Farm corrosion control purposes, while the VDS composite was characterized primarily for Tank Closure Cesium Removal (TCCR) purposes.

41 CFR 102-74.75 - May Federal agencies sell tobacco products in vending machines in Government-owned and leased space?

Science.gov (United States)

2010-07-01

... sell tobacco products in vending machines in Government-owned and leased space? 102-74.75 Section 102... Services § 102-74.75 May Federal agencies sell tobacco products in vending machines in Government-owned and leased space? No. Section 636 of Public Law 104-52 prohibits the sale of tobacco products in vending...

7 CFR 981.10 - Almonds received for his own account.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Almonds received for his own account. 981.10 Section... SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE ALMONDS GROWN IN CALIFORNIA Order Regulating Handling Definitions § 981.10 Almonds received for his own account...

Appearance of medial plica of the knee on MR images

International Nuclear Information System (INIS)

Barton, J.; Pope, C.F.; Jokl, P.; Lynch, K.

1989-01-01

To assess the appearance of the abnormal plica, a rare but important cause of knee pain, the authors have reviewed 1.5-T MR images of 17 patients (mean age, 33 years) who had arthroscopically confirmed abnormal plicae involving the medial aspect of the patella pouch. Asymmetry in the medial wall of the patella pouch was seen in 17 of 17; 10 of 17 had a discernible edge, and four of 17 had sufficient fluid to surround the plica. When sufficient intraarticular fluid was present, the plica was easily detected. Asymmetry in the medial wall of the patella pouch was a helpful MR characteristic to account for unexplained knee pain

75 FR 11627 - Order Granting Temporary Exemptions From Certain Government Securities Act Provisions and...

Science.gov (United States)

2010-03-11

... DEPARTMENT OF THE TREASURY Order Granting Temporary Exemptions From Certain Government Securities... Department of the Treasury (Treasury) is granting temporary exemptions from certain Government Securities Act...).pdf. \\8\\ 75 FR 4626, January 28, 2010 Order Granting a Temporary Exemption from Certain Government...

MR imaging in hemophilic arthropathy

International Nuclear Information System (INIS)

Baunin, C.; Railhac, J.J.; Younes, I.; Gaubert, J.; DuBoullay, C.; Dirat, G.; Robert, A.

1990-01-01

This paper reports on twenty children with hemophilia examined to determine if MR imaging could be used to assess hemophilic arthropathy. Twenty-eight joints were imaged (17 knees, 10 ankles, 1 elbow) with plain radiography, US, CT, and MR imaging. The results were compared with the surgical view and histologic study of the articular components when synovectomy was done. These results show the usefulness of MR imaging: fluid collections in the joint space were evaluated, and it was possible to distinguish blood from inflammatory fluid. Synovial hypertrophy was appreciated, and findings correlated well with histologic study. Anomalies of articular cartilage, joint-space narrowing, and bone lesions were demonstrated early, when plain radiography findings were still normal

Bladder carcinoma. Apport MR imaging

International Nuclear Information System (INIS)

Roy, C.; Spittler, G.; Jacqmin, D.; Morel, M.

1991-01-01

Bladder carcinoma is the second most commun cause of urogenital tumor. It is suspected by abdominal ultrasound and prouved by cystoscopy with biopsy. At present, MR Imaging is the most accurate diagnostic modality for loco-regional staging. Urography is still useful to appreciate urinary tract [fr

Governing Board of the Pension Fund

CERN Multimedia

2005-01-01

The Governing Board of the Pension Fund held its 133rd and 134th meetings on 20 April and 17 May respectively. The President of the CERN Council, Professor E. Iarocci, attended part of the first of these two meetings in order to inform the members of the Governing Board in person of the decisions affecting the Pension Fund taken at the March Session of Council. He underlined that the Council, meeting in Restricted Session, had approved an amendment to the procedure for the appointment of the Chairman of the Governing Board of the Pension Fund as well as the setting of a limit on the terms of office of members of the Board. He further informed the Board that the Council had unanimously decided to set up a new Working Group, "Osnes II", composed of four Council representatives (Professor E. Osnes, (Chair), Professor J. Niederle, Mr C. Van Riel and Mr P. Williams) and of four Fund members: one member appointed by the Director-General (Dr E. Chiaveri); one member appointed by the Staff Association (Dr J.-P. Math...

MR imaging findings of patients with mesial temporal sclerosis

Energy Technology Data Exchange (ETDEWEB)

Kim, Min Jung; Kim, Sun Yong; Suh, Jung Ho [School of Medicine, Ajou University, Suwon (Korea, Republic of)

2000-06-01

To evaluate the MR imaging findings of patients with mesial temporal sclerosis. We retrospectively reviewed the MR imaging findings of 116 patients diagnosed by MRI as suffering from mesial temporal sclerosis. In 18 of these, the condition was also histologically proven. Among the 116 patients, volume loss of the hippocampus was found in 95 (81.9%) and signal changes of the hippocampus in 53 (45.7%). Decreased signal intensity in the hippocampus on T1-weighted images was found in 13 (11.2%) and increased signal on T2-weighted images in 50 (43.1%). Signal abnormality in the hippocampus on both T1- and T2-weighted images was found in ten, and associated extrahippocampal abnormalities, as follows, in 20 (17.2%): atrophy of fornix (n=3D10), atrophy of the mammillary body (n=3D8), atrophy of the amygdala (n=3D10), atrophy or increased T2 signal intensity of the anterior thalamic nuclei (n=3D2), atrophy of the cingulate gyrus (n=3D2), atrophy or increased signal intensity of the anterior temporal lobe (n=3D8), and cerebral hemiatrophy (n=3D4). A high T2 signal and atrophy of the hippocampus are the most common and important MRI findings of mesial temporal sclerosis. Other abnormal findings, if any, which may be found in extrahippocampal structures such as the fornix, mammillary body and temporal lobe, should, however, also be carefully observed. (author)

Functional evaluation of transplanted kidneys by Gd-DTPA enhanced turbo FLASH MR imaging

International Nuclear Information System (INIS)

Nakashima, Rumi; Yamashita, Yasuyuki; Tomiguchi, Seiji; Tsuji, Akinori; Takahashi, Mutsumasa

1996-01-01

We evaluated the usefulness of dynamic turbo FLASH MR imaging in the differential diagnosis of complications after renal transplantation in 17 patients (10 from living relatives and 7 from cadavers). Coronal turbo FLASH dynamic images were obtained every 5 sec for 5 min after an intravenous bolus injection of Gd-DTPA. Corticomedullary differentiation (CMD) on spin echo coronal T 1 -weighted images and MR renogram patterns of the renal cortex and medulla were obtained for quantitative analysis of the Gd-DTPA-enhanced dynamic turbo-FLASH images. The signal intensity ratio of the medulla to cortex after Gd-DTPA enhancement was compared among four groups: normal (n=9), acute tubular necrosis (ATN) or cyclosporine A (CyA) tubulopathy (n=6), acute rejection (AR) in the living related donor kidney (n=4), and AR in the cadaveric kidney (n=5). Although loss of CMD was seen in severe renal dysfunction in the transplanted kidneys, there was considerable overlap among the four groups. On dynamic study, there was significant differences in the signal intensity ratio of the medulla to cortex between normally functioning kidneys or ATN/CyA tubulopathy and AR (p<0.01). In patients with severe renal dysfunction, the arterial cortical peak was indistinct. In conclusion, MR renograms obtained from dynamic turbo FLASH MR imaging played a significant role in evaluating dysfunction of the renal transplant. (author)

Drug-induced MR urography: the effects of furosemide and intravenous saline injection on MR urography of obstructed and non-obstructed urinary tract

Energy Technology Data Exchange (ETDEWEB)

Park, Jeong Ha; Lee, Myung Jun; Lee, Chang Joon [National Medical Center, Seoul (Korea, Republic of)

2001-10-01

To determine the usefulness of MR urography technique for the evaluation of urinary systems in patients with obstructed urinary tract and normal volunteers with non-obstructed urinary tract after intravenous normal saline and diuretic injection. Three normal volunteers and 12 patients with urinary tract obstruction [ureteral calculi (n=8), extraurinary mass (n=1), ureteral tumor invasion (n=3)] underwent MR urography using a 1.0T scanner and a 2D non-breath-hold heavily T2-weighted fast spin-cho sequence. These acquisition were post-processed with a maximum intensity projection (MIP) algorithm. Two acquisitions were performed, the first prior to saline solution infusion following standard MR urography procedures, and the second, within 2-3 minutes of the infusion of 250 ml saline solution followed by 20 mg of Lasix administered intravenously. For this latter, drug-induced MR urography procedures were followed. In healthy volunteer (n=3) and those experiencing partial obstruction (n=4) by a urinary stone, drug-induced MR urography provided better images of the urinary tract than did standard MR urography. In those in whom a urinary stone or tumor had caused complete obstruction (n=8), standard MR urography provided good images, as did drug-induced MR urography. In patients with a partially or non-obstructed urinary tract, drug-induced MR urography provided better anatomic and functional details of the kidney and urinary tract than did standard MR urography. In those experiencing complete obstruction of the urinary tract, however, standard or drug-induced MR urography permitted very adequate evaluation of the tract, and drug-induced MR urography was unnecessary.

MR imaging findings of diffuse axonal injury: comparison of T2-weighted gradient images and T1- and T2-weighted spin-echo images

Energy Technology Data Exchange (ETDEWEB)

Park, Seo Young; Lee, Ghi Jai; Kim, Jeong Seok; Shim, Jae Chan; Kim, Ho Kyun [Inje Univ. College of Medicine, Seoul (Korea, Republic of)

1998-10-01

To compare T2-weighted images with spin-echo T1- and turbo spin-echo (TSE) T2-weighted images in patients with diffuse axonal injury(DAI). Using a 1.0T MR unit, SE T1-, TSE T2-, and and FLASH T2-weighted images were obtained from 69 patients with a history of head trauma. In 18MR images of 17 patients with imaging findings of DAI, T2-weighted images were retrospectively compared with SE T1- and TSE T2-weighted images. The interval between trauma and MR scan varied from 5 days to 24(mean, 11) months. Focusing on the number of lesions, and their location and signal intensity, as weel as associated findings, three images were simultaueously evaluated. In 18 MR images of 17 patients with MR imaging findings of DAI, 21 lesions were detected on T1-weighted images, 28 on TSE T2-weighted images, and 70 on T2-weighted images;the last of these revealed all lesions detected on the other two. Most lesions were hypointense on T1-weighted images(17/21), hyperintense on TSE T2-weighted (21/28), and hypointense on T2-weighted (63/70). Common locations for DAI were the frontal lobe (n=3D35) and corpus callosum (n=3D22). Associated brain injuries were cortical contusion (n=3D5), brainstem injury (n=3D3), deep gray matter injury (n=3D2), and subdural hematoma(n=3D1). In patients with DAI. T2-weighted images can detect more lesions and associated petechial hemorrhage than can TSE T2-weighted images. This modality is thus useful for the evaluation of patients with head trauma.=20.

7 CFR 1160.505 - Patents, copyrights, inventions and publications.

Science.gov (United States)

2010-01-01

... funds collected under the provisions of this subpart are the property of the United States Government as... the rental, sale, leasing, franchising, or other uses of such patents, copyrights, inventions, or...

United States Army Medical Department Journal, January-March 2010

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2010-03-01

uti - lization of government-owned inventions by licensing inventions to the private sector. Licensing of federally owned inventions and other...physical therapists, podiatrists, optometrists, clinical dieticians, social workers, clinical pharmacists , clinical psychologists, occupational

Evaluation of ambiguous genitalia with MR imaging

International Nuclear Information System (INIS)

Secaf, E.; Nuruddin, R.; Hricak, H.; Conte, F.A.

1989-01-01

To assess the potential of MR imaging in the evaluation of patients with ambiguous genitalia. Twenty-three consecutive patients with ambiguous genitalia at birth or phenotypic anomalies at puberty were included in this study. MR imaging was performed on a 1.5-T unit using T1- (600/30) and T2- (2,500/70) weighted sequences. In patients aged 5 years or less, 3-mm contiguous sagittal and transaxial sections were obtained. The same imaging planes at 5-mm intervals were obtained in older patients. MR findings were compared to those of surgery (n = 14) or biochemical assays (n = 9). Diagnoses included true hermaphroditism (n = 2), pseudohermaphroditism (n = 6), Turner syndrome (n = 2), testicular feminization (n = 2), adrenogenital syndrome (n = 3), vaginal agenesis (n = 3), cloacal abnormality (n = 2), microphallus (n = 2), and double phallus (n = 1. MR imaging correctly identified the presence or absence of the vagina (n = 10) and uterus (n = 9), thus helping in the diagnosis and management of patients with ambiguous genitalia. Demonstration of development of corpora cavernosa, corpora spongiosa, undescended testis, or partial vaginal agenesis assisted in the surgical approach

7 CFR 1230.88 - Patents, copyrights, inventions, and publications.

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2010-01-01

... provisions of this subpart shall be the property of the United States Government as represented by the Board..., leasing, franchising, or other uses of such patents, copyrights, inventions, or publications inure to the...

78 FR 75335 - Intent To Grant an Exclusive License for a U.S. Government-Owned Invention

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2013-12-11

..., ``Automated Inhalation Toxicology Exposure System and Method,'' and related foreign rights. The intended licensee is Biaera Technologies, LLC, with its principal place of business at 277 Eastern Boulevard North, Suite 3, Hagerstown, MD 21740. ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command...

78 FR 1848 - Intent To Grant an Exclusive License of a U.S. Government-Owned Invention

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2013-01-09

..., entitled ``Method of Diagnosing of Exposure to Toxic Agents by Measuring Distinct Pattern in the Levels of..., Inc., with its principal place of business at 4938 Hampden Lane 319, Bethesda, Maryland 20814-2914. ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, ATTN: Command Judge Advocate, MCMR-JA...

75 FR 69060 - Intent To Grant an Exclusive License for a U.S. Government-Owned Invention

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2010-11-10

.... 12/670,250, entitled ``Obstetrics Simulation and Training Method and System,'' filed on January 22... Company, Inc., with its principal place of business at 14700 SW 136 Street, Miami, FL 33196- 5691. ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, ATTN: Command Judge Advocate, MCMR-JA...

75 FR 70915 - Intent To Grant an Exclusive License for a U.S. Government-Owned Invention

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2010-11-19

... Vaccine, Methods of Making and Use Thereof,'' to Merck Sharp & Dohme Corp., with its principal place of business at One Merck Drive, Whitehouse Station, NJ 08889-3400. ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick...

MR imaging of avascular necrosis of the femoral head: Correlation with radiography, radionuclide scan and clinical finding

Energy Technology Data Exchange (ETDEWEB)

Kim, Jung Sik; Woo, Young Hoon; Joo, Yang Goo; Lee, Sung Moon; Zeon, Seok Kil; Suh, Soo Jhi; Kang, Chang Soo [School of Medicine, Keimyung University, Taegu (Korea, Republic of)

1992-03-15

To explore the ability of magnetic resonance imaging(MRI) in the diagnosis of avascular necrosis(AVN) of the femoral head, we compared appearances on MRI of 85 proven AVN lesions with those on radiographs(n=79) and radionuclide scans(n=75). Clinical symptoms(n=85) were also correlated. All MR studies included coronal and axial T1WI and coronal T2WI. All lesions involved the anterosuperterior aspect of the femoral head and were surrounded by a low signal intensity rim on both T1 and T2WI. The signal intensity of the lesions was variable depending on the disease course, and the lesions were divided into four classes according to the classification suggested by Mitchell. Radiographs were normal in 16%(13/79) of the lesions which were in MR class A(10), B(1), C(2). The radionuclide scans showed normal in 16%(12/75) of the lesions which were in MR class A(8). B(1), C(2), D(1). On the other hand, 93% of the lesions with MR class A(27/29) showed stage 1 and 2 lesions on radiographs. Clinical symptoms were absent in 25%(21/85) of the lesions, and among these,81%(17/21) were MR class A. Conclusively, MR is superior to the radiography and radionuclide scan in the early detection of AVN, and can also show the exact location, extent and signal characteristic of the lesion. Therefore, Mr is essential in diagnosis and management of AVN.

MR imaging of avascular necrosis of the femoral head: Correlation with radiography, radionuclide scan and clinical finding

International Nuclear Information System (INIS)

Kim, Jung Sik; Woo, Young Hoon; Joo, Yang Goo; Lee, Sung Moon; Zeon, Seok Kil; Suh, Soo Jhi; Kang, Chang Soo

1992-01-01

To explore the ability of magnetic resonance imaging(MRI) in the diagnosis of avascular necrosis(AVN) of the femoral head, we compared appearances on MRI of 85 proven AVN lesions with those on radiographs(n=79) and radionuclide scans(n=75). Clinical symptoms(n=85) were also correlated. All MR studies included coronal and axial T1WI and coronal T2WI. All lesions involved the anterosuperterior aspect of the femoral head and were surrounded by a low signal intensity rim on both T1 and T2WI. The signal intensity of the lesions was variable depending on the disease course, and the lesions were divided into four classes according to the classification suggested by Mitchell. Radiographs were normal in 16%(13/79) of the lesions which were in MR class A(10), B(1), C(2). The radionuclide scans showed normal in 16%(12/75) of the lesions which were in MR class A(8). B(1), C(2), D(1). On the other hand, 93% of the lesions with MR class A(27/29) showed stage 1 and 2 lesions on radiographs. Clinical symptoms were absent in 25%(21/85) of the lesions, and among these,81%(17/21) were MR class A. Conclusively, MR is superior to the radiography and radionuclide scan in the early detection of AVN, and can also show the exact location, extent and signal characteristic of the lesion. Therefore, Mr is essential in diagnosis and management of AVN

Inventing the future: Energy and the CO2 "greenhouse" effect

Science.gov (United States)

Davis, E. E., Jr.

Dennis Gabor, A winner of the Nobel Prize for Physics, once remarked that man cannot predict the future, but he can invent it. The point is that while we do not know with certainty how things will turn out, our own actions can play a powerful role in shaping the future. Naturally, Gabor had in mind the power of science and technology, and the model includes that of correction or feedback. It is an important: Man does not have the gift of prophecy. Any manager or government planner would err seriously by masterminding a plan based unalterably on some vision of the future, without provision for mid-course correction. It is also a comforting thought. With man's notorious inability to create reliable predictions about such matters as elections, stock markets, energy supply and demand, and, of course, the weather, it is a great consolation to feel that we can still retain some control of the future.

MR arthrographic findings in tenosynovitis of the long bicipital tendon of the shoulder

International Nuclear Information System (INIS)

Gueckel, C.; Nidecker, A.

1998-01-01

Purpose. To assess the MR arthrographic findings of bicipital tenosynovitis in correlation with arthroscopy. Design and patients. The shoulder MR arthrographies of 500 consecutive patients were retrospectively analyzed for signs of bicipital tenosynovitis and associated pathologies. Forty patients (8%) had MR evidence of bicipital tenosynovitis, but only 17 (3%) with arthroscopic confirmation were included in the study. The MR findings in these patients were compared with those of 10 patients with rotator cuff lesions but arthroscopically normal long biceps tendons. MR arthrography was performed with 10-15 ml of a 250 mmol/l gadoterate meglumine (Gd-DOTA) solution injected under fluoroscopic guidance, and transaxial, oblique coronal and sagittal MR sequences were obtained. Results. All 17 patients showed one or more abnormal findings: signal increase in the tendon with or without fusiform distension was seen in 12, surface irregularities in six, adhesions in 11 and noncommunicating effusions of the tendon sheath in six. Associated abnormalities of the rotator cuff were present in 16 while the seventeenth patient had glenohumeral synovitis without rotator cuff pathology. MR arthrograms correlated with arthroscopic findings in the joint but comparison was not possible in the intertubercular groove portion of the biceps tendon. None of the 10 patients with an arthroscopically normal biceps tendon showed any of the MR findings of bicipital tenosynovitis. Conclusion. Bicipital tenosynovitis is detectable by MR arthrography. In most cases it is an associated finding of rotator cuff abnormalities and likely to have a similar etiology. When lesions of the anterior rotator cuff are recognized, the biceps tendon should be scrutinized for inflammatory changes. (orig.)

MR-guided facet joint injection therapy using an open 1.0-T MRI system: an outcome study

International Nuclear Information System (INIS)

Freyhardt, Patrick; Bucourt, Maximilian de; Maurer, Martin; Renz, Diane; Gebauer, Bernhard; Hamm, Bernd; Streitparth, Florian; Hartwig, Tony; Teichgraeber, Ulf K.M.

2013-01-01

To evaluate the accuracy, safety and efficacy of magnetic resonance imaging (MRI)-guided facet joint injection therapy using a 1.0-T open MRI. One hundred and sixty-six facet joint blocks in 45 patients with lower back pain were performed under MR fluoroscopic guidance using a proton-density-weighted turbo-spin-echo sequence. An in-room monitor, wireless MR-mouse for operator-controlled multiplanar navigation, a flexible surface coil and MR-compatible 20-G needle were used. Clinical outcome was evaluated by questionnaire before intervention and after 1 week, 3, 6 and 12 months using a numerical visual analogue scale (VAS). All facet joint blocks were considered technically successful with distribution of the injectant within and/or around the targeted facet joint. No major complications occurred. The final outcome analysis included 38 patients. An immediate effect was reported by 63 % of the patients. A positive mid-/long-term effect was seen in 13 patients (34 %) after 6 months and in 9 patients (24 %) after 12 months. Mean VAS was reduced from 7.1 ± 1.7 (baseline) to 3.5 ± 2.2, 4.1 ± 3.0, 3.8 ± 2.9 and 4.6 ± 2.9 at 1 week, 3, 6 and 12 months (P < 0.01). MR-guided facet joint injection therapy of the lumbosacral spine is accurate, safe and efficient in the symptomatic treatment of lower back pain. (orig.)

45 CFR 7.1 - Duty of employee to report inventions.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Duty of employee to report inventions. 7.1 Section 7.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION EMPLOYEE INVENTIONS § 7.1 Duty of employee to report inventions. Every Department employee is required to report to...

Was the Monetarist Tradition Invented?

OpenAIRE

George S. Tavlas

1998-01-01

In 1969, Harry Johnson charged that Milton Friedman 'invented' a Chicago oral quantity theory tradition, the idea being that in order to launch a monetarist counter-revolution, Friedman needed to establish a linkage with pre-Keynesian orthodoxy. This paper shows that there was a distinct pre-Keynesian Chicago quantity-theory tradition that advocated increased government expenditure during the Great Depression in order to put money directly into circulation. This policy stance distinguished th...

Evaluación por rendimiento de 12 genotipos promisorios de fríjol voluble (Phaseolus vulgaris L. tipo Bola roja y Reventón para las zonas frías de Colombia

Directory of Open Access Journals (Sweden)

López Jesús Edgardo

2006-12-01

Full Text Available

10.0pt; font-family: ";Cambria";,";serif";; mso-ascii-theme-font: major-latin; mso-fareast-font-family: Baskerville; mso-hansi-theme-font: major-latin; mso-bidi-font-family: Baskerville;">El fríjol común (10.0pt; font-family: ";Cambria";,";serif";; mso-ascii-theme-font: major-latin; mso-fareast-font-family: Baskerville-Italic; mso-hansi-theme-font: major-latin; mso-bidi-font-family: Baskerville-Italic;">Phaseolus vulgaris 10.0pt; font-family: ";Cambria";,";serif";; mso-ascii-theme-font: major-latin; mso-fareast-font-family: Baskerville; mso-hansi-theme-font: major-latin; mso-bidi-font-family: Baskerville;">L. es un alimento básico en la región Andina por ser una fuente rica en proteína y de bajo costo. La investigación para incrementar rendimientos en esta leguminosa es una opción para mejorar la competitividad en el mercado mundial. El objetivo principal de este trabajo fue evaluar por rendimiento los genotipos promisorios de fríjol voluble, tipos Bola roja y Reventón, para las zonas frías de Colombia mediante el análisis de sendero. Se realizó un diseño de bloques completos al azar con tres réplicas para evaluar 10 genotipos promisorios de fríjol voluble. El análisis de sendero para el rendimiento por planta y las correlaciones entre el rendimiento y sus componentes mostraron que el carácter número de vainas por planta es el de mayor importancia sobre la determinación del rendimiento, en comparación con los caracteres peso de 100 semillas y número de semillas por vaina, tanto en los genotipos de fríjol voluble tipo Bola roja como tipo Reventón. 

The Software Invention Cube: A classification scheme for software inventions

NARCIS (Netherlands)

Bergstra, J.A.; Klint, P.

2008-01-01

The patent system protects inventions. The requirement that a software invention should make ‘a technical contribution’ turns out to be untenable in practice and this raises the question, what constitutes an invention in the realm of software. The authors developed the Software Invention Cube

MR arthrographic findings in tenosynovitis of the long bicipital tendon of the shoulder

Energy Technology Data Exchange (ETDEWEB)

Gueckel, C. [Department of Radiology, University Hospital of Basel, Petersgraben 4, CH-4031 Basel (Switzerland); Nidecker, A. [MRI Institut Rebgasse, Untere Rebgasse 18, CH-4058 Basel (Switzerland)

1998-01-01

Purpose. To assess the MR arthrographic findings of bicipital tenosynovitis in correlation with arthroscopy. Design and patients. The shoulder MR arthrographies of 500 consecutive patients were retrospectively analyzed for signs of bicipital tenosynovitis and associated pathologies. Forty patients (8%) had MR evidence of bicipital tenosynovitis, but only 17 (3%) with arthroscopic confirmation were included in the study. The MR findings in these patients were compared with those of 10 patients with rotator cuff lesions but arthroscopically normal long biceps tendons. MR arthrography was performed with 10-15 ml of a 250 mmol/l gadoterate meglumine (Gd-DOTA) solution injected under fluoroscopic guidance, and transaxial, oblique coronal and sagittal MR sequences were obtained. Results. All 17 patients showed one or more abnormal findings: signal increase in the tendon with or without fusiform distension was seen in 12, surface irregularities in six, adhesions in 11 and noncommunicating effusions of the tendon sheath in six. Associated abnormalities of the rotator cuff were present in 16 while the seventeenth patient had glenohumeral synovitis without rotator cuff pathology. MR arthrograms correlated with arthroscopic findings in the joint but comparison was not possible in the intertubercular groove portion of the biceps tendon. None of the 10 patients with an arthroscopically normal biceps tendon showed any of the MR findings of bicipital tenosynovitis. Conclusion. Bicipital tenosynovitis is detectable by MR arthrography. In most cases it is an associated finding of rotator cuff abnormalities and likely to have a similar etiology. When lesions of the anterior rotator cuff are recognized, the biceps tendon should be scrutinized for inflammatory changes. (orig.) With 4 figs., 4 tabs., 22 refs.

10 CFR 600.7 - Small and disadvantaged and women-owned business participation.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Small and disadvantaged and women-owned business... ASSISTANCE RULES General § 600.7 Small and disadvantaged and women-owned business participation. (a) DOE encourages the participation in financial assistance awards of small businesses, including those owned by...

78 FR 27882 - VA Veteran-Owned Small Business (VOSB) Verification Guidelines

Science.gov (United States)

2013-05-13

... Verification Self-Assessment Tool that walks the veteran through the regulation and how it applies to the...) Verification Guidelines AGENCY: Department of Veterans Affairs. ACTION: Advanced notice of proposed rulemaking... regulations governing the Department of Veterans Affairs (VA) Veteran-Owned Small Business (VOSB) Verification...

Estudio de corrosión bajo tensión en los aceros inoxidables 17-4PH y 17-7PH en presencia de NaCl y NaOH (20 % a 90 °C

Directory of Open Access Journals (Sweden)

Gaona-Tiburcio, Citlalli

2000-04-01

Full Text Available One of the problems that affects to the electric industry is the not programmed stoppages in the power plants, due to the failure of any main component: boiler, turbine and generator. In the turbine, the combined action of a corrosive agent (humid polluted vapor and a mechanical effort generally will result in Stress Corrosion Cracking (SCC. In this work the SCC susceptibility of the precipitation hardening stainless steels 17-4PH and 17- 7PH, thoroughly used in steam turbine blades of power stations is analyzed. The specimens were tested in the presence of NaCl and NaOH (20 % to 90 °C and different pH. The CERT test (Constant Extension Rate Test was used, at 10^-6 s^-1 supplementing it with electrochemical noise; the aim was to identify the conditions of maximum susceptibility and the performance of the studied materials. The fractographic analysis revealed ductile and brittle fracture. Intergranular crackings, characteristic of the anodic dissolution mechanism of the material was observed. Nevertheless, the main mechanism responsible the failure was hydrogen embrittlement.

Uno de los problemas que afecta a la industria eléctrica es el de los paros no programados en las plantas generadoras de electricidad, debidos al fallo de algún componente principal: caldera, turbina y generador. En la turbina, la acción combinada de un agente corrosivo (vapor húmedo contaminado y un esfuerzo mecánico, generalmente provocará corrosión bajo tensión (CBT. En este trabajo se analiza la susceptibilidad a la CBT de los aceros inoxidables, endurecibles por precipitación, 17-4PH y 17-7PH, ampliamente usados en alabes de turbina de vapor de centrales termoeléctricas. Las muestras se ensayaron en presencia de NaCl y NaOH (20 % a 90 °C, y distintos valores de pH. Se empleó el ensayo CERT (Constant Extensión Rate Test, a velocidades de 10^-6 s^-1, complementándolo con ruido electroquímico, buscando

25 CFR 213.17 - Government reserves right to purchase minerals produced.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Government reserves right to purchase minerals produced... Leases § 213.17 Government reserves right to purchase minerals produced. In time of war or other public... prevailing market price on the date of sale all or any part of the minerals produced under any lease. Rents...

Valuation of dynamic MR imaging for diagnosis of pituitary microadenomas

International Nuclear Information System (INIS)

Lu Wu; Zhou Shengli; Liu Yusheng

2003-01-01

Objective: To evaluate the use of keyhole dynamic magnetic resonance (MR) imaging in evaluation of pituitary microadenomas. Methods: Fifty-three patients with pituitary microadenomas proved by operation or clinical findings such as headache, amenorrhea, lactating, fat or acromegaly were retrospectively studied on dynamic MR, conventional contrast enhanced MR, and unenhanced MR. Then the image data were analyzed by two experienced doctors who didn't know the details and three degrees were made as follows: grade 0, no evidence of the tumor; grade I, asymmetry signals in the pituitary; and grade II, nodulated or sheets signals in the pituitary. The grading data were compared with statistical methods. Results: In dynamic MR grading system: grade 0 was revealed in 1 patient, grade I in 29 patients and grade II in 23 patients. In conventional enhanced MR: grade 0 in 26 patients, grade I in 17 patients and grade II in 10 patients. In conventional unenhanced MR: grade 0 in 39 patients, grade I in 10 patients and grade II in 4 patients. The diagnostic rate of dynamic MR, conventional enhanced MR, and unenhanced MR was 98.1%, 51.9%, and 26.4%, respectively. (P < 0.005). Dynamic MR can increase the grade of tumor compared to the other two, which is significant statistically. Conclusion: Keyhole dynamic MR can increase the diagnostic accuracy of pituitary microadenomas while decreasing the uncertainty. So dynamic MR should become a routine examination for pituitary microadenoma when suspected by clinical findings but negative in conventional MR

MR staging of malignant musculoskeletal tumors: An experimental study on MR and pathologic correlation of rabbit VX-2 carcinoma

International Nuclear Information System (INIS)

Kang, Heung Sik; Chung, Sung Hoon; KIm, Cheol Woo; Kim, Seong Moon; Im, Jung Gi; Han, Man Chung

1993-01-01

To evaluate the reliability of MR imaging in tissue characterization and depiction of tumor boundaries, we performed MR pathologic correlation using parosteally implanted VX-2 carcinoma in 17 rabbit thighs. T1-weighted, T2-weighted and Gd-DTPA enhanced T1-weighted axial images were obtained 10-30 days after tumor implantation. After the animals were killed, frozen and sectioned along the MR imaging planes, and histopathologic examination were done. For accurate MR pathologic correlation, rabbit were fixed on the cardboard plate to minimize position change during the procedure. Tumor boundaries depicted on MR images were larger than those depicted on the specimen. Small tumors were surrounded by capsule-like loose connective tissue. Loose connective tissue became compact with tumor growth. This connective tissue showed high signal intensity on both T2-weighted and Gd-DTPA enhanced T1-weighted images. Muscle atrophy with fatty tissue accumulation around the tumor also contributed to the high signal intensity on MR images. Peritumoral edema and inflammatory reaction were not remarkable. Six of 8 cases with bone marrow fibrosis were detected on MR images. We concluded that peritumoral loose connective tissue and muscle atrophy exaggerated the size of experimentally induced malignant musculoskeletal tumors on MR images

MR imaging of simple bone cysts in children: not so simple

Energy Technology Data Exchange (ETDEWEB)

Margau, R. [Faculty of Medicine, University of Toronto, Toronto, ON (Canada); Babyn, P. [Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON (Canada); Cole, W.; Lee, F. [Division of Orthopaedic Surgery, Department of Surgery, The Hospital for Sick Children and University of Toronto, Toronto, ON (Canada); Smith, C. [Department of Pathology, The Hospital for Sick Children and University of Toronto, Toronto, ON (Canada)

2000-08-01

Objective. The unicameral bone cyst (UBC) is a common cystic bone lesion seen in children. We review and summarize its MR findings, focusing on their appearance following contrast enhancement, and correlating them to known histologic features of UBC. Subjects and methods. A retrospective review of 20 cases (13 boys, 7 girls; age range, 1-17 years; mean age, 8.9) diagnosed as UBC was conducted. Clinical histories, radiographic and MR features, follow-up data, and available pathologic findings were noted. Results. At initial presentation 18 (90 %) of the patients with UBC had a history of acute or remote pathologic fracture. Cysts with history of fracture displayed heterogeneous fluid signals on T1- (n = 9, 50 %), and T2-weighted (n = 15, 83 %) MR images. Gadolinium-enhanced images were obtained in 15 of the 18 UBC cases with history of previous fracture. All showed enhancement with focal, thick peripheral, heterogeneous, or subcortical patterns. Focal nodules of homogeneous enhancement (diameter > 1 cm) within the UBC (n = 5) correlated with areas of ground-glass opacification on plain film. Other interesting MR features were fluid-fluid levels (n = 11), ''fallen-leaf'' sign (n = 1), soft-tissue changes (n = 2), and detection of septations not seen on plain film (n = 2). Conclusion. UBCs frequently appear complicated on MR imaging, with heterogeneous fluid signals and regions of nodular and thick peripheral enhancement related to previous pathologic fracture and early healing. (orig.)

MR imaging of simple bone cysts in children: not so simple

International Nuclear Information System (INIS)

Margau, R.; Babyn, P.; Cole, W.; Lee, F.; Smith, C.

2000-01-01

Objective. The unicameral bone cyst (UBC) is a common cystic bone lesion seen in children. We review and summarize its MR findings, focusing on their appearance following contrast enhancement, and correlating them to known histologic features of UBC. Subjects and methods. A retrospective review of 20 cases (13 boys, 7 girls; age range, 1-17 years; mean age, 8.9) diagnosed as UBC was conducted. Clinical histories, radiographic and MR features, follow-up data, and available pathologic findings were noted. Results. At initial presentation 18 (90 %) of the patients with UBC had a history of acute or remote pathologic fracture. Cysts with history of fracture displayed heterogeneous fluid signals on T1- (n = 9, 50 %), and T2-weighted (n = 15, 83 %) MR images. Gadolinium-enhanced images were obtained in 15 of the 18 UBC cases with history of previous fracture. All showed enhancement with focal, thick peripheral, heterogeneous, or subcortical patterns. Focal nodules of homogeneous enhancement (diameter > 1 cm) within the UBC (n = 5) correlated with areas of ground-glass opacification on plain film. Other interesting MR features were fluid-fluid levels (n = 11), ''fallen-leaf'' sign (n = 1), soft-tissue changes (n = 2), and detection of septations not seen on plain film (n = 2). Conclusion. UBCs frequently appear complicated on MR imaging, with heterogeneous fluid signals and regions of nodular and thick peripheral enhancement related to previous pathologic fracture and early healing. (orig.)

MR cholangiopancreatography. Comparison of images obtained with 1.0 and 1.5 tesla units

International Nuclear Information System (INIS)

Yasui, Masayasu; Ito, Katsuyoshi; Koike, Shinji; Matsunaga, Naofumi

2002-01-01

The purpose of this study was to compare the image quality and visualization obtained in MR cholangiopancreatography (MRCP) using different high-field strength (1.0 vs. 1.5 Tesla) MR units and to assess the effect of field strength on MRCP. This study population included 10 healthy volunteers and 37 patients suspected of having pancreatobiliary diseases. MRCP images were obtained using two MR units with different high-field strengths (1.0 and 1.5 Tesla), with half-Fourier acquisition single-shot turbo spin-echo (HASTE) and rapid acquisition by relaxation enhancement (RARE) sequences. The image quality and visualization of each portion of the pancreatobiliary system were graded and recorded using a four-point scale. Additionally, the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were measured. The SNR and CNR in HASTE sequences acquired with the 1.5 Tesla (T) unit were significantly higher than those acquired with the 1.0 T unit (p=0.001). In qualitative analysis, there were no statistically significant differences in image quality or visualization of the ducts in either HASTE or RARE sequences between 1.0 T and 1.5 T. Our study showed that visual image quality provided by MRCP was equivalent at 1.0 and 1.5 T. (author)

MR study of acute myocardial infarction with injection of Gd-DOTA (Fifteen patients)

International Nuclear Information System (INIS)

Richoz, B.; Delcour, C.; Depelchin, P.; Lenaers, A.; Jacquemin, C.; Gusella, P.; Struyven, J.; Richoz, B.

1990-01-01

We studied 15 patients 4 to 8 days after myocardial infarction by using ECG gated MR before and after administration of 0.2 mmol/kg Gd-DOTA. The diagnosis in each patient was confirmed by electrocardiographic criteria, elevated levels of fractionated creatine kinase (CK) isoenzyme, thallium scintigraphy, ventriculography and coronarography. T1-weighted, spin-echo images, were obtained before and immediately after injection of Gd-DOTA and were repeated 15 min later. The site of infarction was visualized in 10 patients as an area of high signal intensity after the injection of Gd-DOTA. Contrast between normal and infarcted myocardium was greatest 15 min after injection. Three patients were excluded because of failure to acquire adequate MR studies. In 2 other patients, the infarct were not detected. Before injection of Gd-DOTA, only 2 infarcts were detected. These results suggest that Gd-DOTA can improve MR visualization and detection of acute myocardial infarction [fr

78 FR 69703 - 10-Day Notice of Proposed Information Collection: Generic Customer Satisfaction Surveys; Physical...

Science.gov (United States)

2013-11-20

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5683-N-102] 10-Day Notice of Proposed Information Collection: Generic Customer Satisfaction Surveys; Physical Inspection Pilot Program...

MR imaging of sports-related muscle pain

International Nuclear Information System (INIS)

Fleckenstein, J.L.; Weatherall, P.T.; Parkey, R.W.; Peshock, R.M.

1988-01-01

Muscle pain following exercise occurs acutely or after a significant delay. MR imaging of the lower extremities was performed in acute strains (N=3); runners after a 30-km marathon (N=10); and sedentary subjects, 3-5 days after brief ankle plantarflexion (N=5). Serum creatine kinase (CK) levels were determined in groups 2 and 3. Abnormal signal intensity was evident in all groups. The increase in CK level was associated in time with onset of signal increase in group 3. MR imaging is useful in defining the distribution, extent, and natural history of exercise-induced muscle injury

17 CFR 274.303 - Form N-27I-2, notice of withdrawal right and statement of charges for variable life insurance...

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2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-27I-2, notice of withdrawal right and statement of charges for variable life insurance contractholders required pursuant to... variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). [41 FR...

The Impact of Governance Practices on the Operating Performance: A Study on the Indonesian State-Owned Enterprises

Directory of Open Access Journals (Sweden)

Dezie L. Warganegara

2012-04-01

Full Text Available This study aims to investigate the corporate governance practices on State-Owned Enterprises (SOEs and to find out their impacts on the operating performance of the firms. This study finds out the substantial improvements of the quality of corporate governance practices in public-listed Indonesian SOEs. Total corporate governance (CG compliance score and each component score show an upward trend improvement. With regard to the relationship between CG compliance and operating performance, as represented by Return on Assets, Net Profit Margin, and Assets Turnover, this study finds out that there is a direct relationship between the governance quality and operating performance. This positive relationship is cpused by the reduction of the operating cost and not coused by the increase of sales or the better use of assets.

The Impact of Governance Practices on the Operating Performance:A Study on the Indonesian State-Owned Enterprises

Directory of Open Access Journals (Sweden)

Dezie L. Warganegara

2012-04-01

Full Text Available This study aims to investigate the corporate governance practices on State-Owned Enterprises (SOEs and to find out their impacts on the operating performance of the firms. This study finds out the substantial improvements of the quality of corporate governance practices in public-listed Indonesian SOEs. Total corporate governance (CG compliance score and each component score show an upward trend improvement. With regard to the relationship between CG compliance and operating performance, as represented by Return on Assets, Net Profit Margin, and Assets Turnover, this study finds out that there is a direct relationship between the governance quality and operating performance. This positive relationship is cpused by the reduction of the operating cost and not coused by the increase of sales or the better use of assets.

Mutiple sclerosios of the spinal cord: MR imaging findings

International Nuclear Information System (INIS)

Kim, Young Hoon; Chang, Kee Hyun; Kim, Sam Soo; Park, Byung Kwan; Seong, Chang Kyu; Han, Moon Hee; Cho, Yong Jin; Jeon, Beom Seok

1998-01-01

To evaluate the MR appearance of multiple sclerosis in the spinal cord. Between January 1990 and December 1996, we retrospectively analyzed 27 spinal MR images of 18 patients in whom-on the basis of Poser's diagnostic critera-multiple sclerosis of the spinal cord had been diagnosed. Eleven patients were men and seven were women, and they were aged between 18 and 58(mean, 37) years. Using T1-weighted sagittal(n=3D27), T2-weighted axial(n=3D26) and sagittal(n=3D27), and contrast enhanced T1-weighted(n=3D14) images, lesions were analyzed for multiplicity, location, length, cross-sectional area and location, cord size, and enhancement pattern. Brain MR images(n=3D15) were also evaluated. In 14 of 18 patients, a solitary lesion was seen on initial MR imaging. Four of the 14 had double lesions, and on follow-up MR imaging at 2-5 months, five were seen to have double lesions. Eleven lesions were found in the cervical cord, and 12 in the thoracic cord, two were in the cervicothoracic and two in the thoracolumbar region. The length of 12 lesions was less than two vertebral heights, while 15 extended for more than two vertebral heights. Six lesions occupied less than 50% of the cross-sectional area of the cord and the other 20 occupied more than 50% of this area. Cord size was enlarged in 17 cases, unchanged in eight, and atrophic in two. Eight lesions in 14 patients who underwent enhanced MR imaging showed focal contrast enhancement; there was patchy enhacement in two, nodular enhancement in two, and linear enhancement in four. Among 15 MR images of the brain, high-signal intensity lesions, compatible with multiple sclerosis, were demonstrated in seven cases. Multiple sclerosis plaques in the spinal cord frequently extend for more than two vertebral body heights of either the cervical or thoracic level, occupy more than 50% of the cross-sectional area and manifest as enlarged cord. But the MR imaging findings, however, are nonspecific. Abnormalities were seen in

MR imaging of sacrococcygeal pilonidal sinus

International Nuclear Information System (INIS)

Kim, Sun Mi; Shin, Myung Jin; Choi, Soo Jung; Kim, Sung Moon

2000-01-01

The purpose of this study is to evaluate the characteristic MR findings of sacrococcygeal pilonidal is simus. Eight MR images of pathologically proven sacrococcygeal pilonidal sinus were retrospectively reviewed [M:F 7:1 ; age range 9-41(median, 17) years]. In all cases, a sacrococcygeal mass was present. Five of the eight patients experienced pain, and in three was discharge. MR findings were evaluated with regard to the location and extent of the lesion, and the presence of sinus or cyst, and the results were compared with the pathologic findings. According to the clinical manifestations, each case was assigned to one of four groups: the first type (n=3) showed dermal thickening with subcutaneous fatty infiltration of the ipsilateral natal cleft while pathologically, a follicular cyst with dermal fibrosis and multiple fatty lobules with fibrous septa were found to be present. In the secone type (n=3), fluid was observed in the sinus tract, while the pathologic findings demonstrated the presence of an abscess in this area. In the third type (n=1), a cystic lesion with air-fluid level was present; pathologically, an abscess was revealed. The fourth type (n=1) showed only a low signal intensity sinus tract on both T1 and T2-weighted images, while the pathologic findings indicated the presence of hairs and follicles within the tract. The MR findings of sacrococcygeal pilonidal sinus depend on the clinical mainfestation and include subcutaneous fatty infiltration, a sinus tract with or without fluid retention, and a cystic lesion with air fluid level. These findings could be helpful for differentiating between this and other sacrococcygeal lesions

MR-Guided PTA in Experimental Bilateral Rabbit Renal Artery Stenosis and MR Angiography Follow-Up Versus Histomorphometry

International Nuclear Information System (INIS)

Le Blanche, Alain-Ferdinand; Rossert, Jerome; Wassef, Michel; Levy, Bernard; Bigot, Jean-Michel; Boudghene, Frank

2000-01-01

Purpose: To assess in vivo 1) MR-guided percutaneous transluminal renal angioplasty (PTRA) in experimental bilateral rabbit renal artery stenosis (RAS); 2) postprocedural follow-up by gadolinium-enhanced MR angiography versus histomorphometry.Methods: Fifteen male NZW rabbits of mean weight 4.0 kg (range 3.5-4.2 kg) underwent bilateral RAS induction by combined overdilation-deendothelialization with a gadolinium-filled balloon, passively MR-guided by the artifact of a 0.014-inch guidewire. After 4 weeks the rabbits were randomized into two groups: group A (n = 8) underwent right-sided PTRA for treatment of RAS, group B (n = 7) underwent left-sided PTRA. After another 4 weeks the rabbits were killed to assess by histomorphometry recurrent stenosis and contralateral induction injury stenosis lesions. Each step was preceded by gadolinium-enhanced three-dimensional MR angiography, and the cortex-to-aorta (C/A) signal intensity ratio was calculated.Results: RAS induction was successful in all cases. Fourteen arteries developed restenosis and 13 only initial stenosis. MR-guided PTRAs were feasible in 22 arteries (73%). For a successful catheterization of the ostium (20 arteries, 66% success rate), 10-25 steps were required. Five to eight steps were required for balloon localization and inflation for each PTRA. The restenosis effect was reflected by a 16% (12%-27%) decrease in C/A values on MR angiograms (p < 0.05).Conclusion: MR guidance and MR angiography represent a feasible, less invasive alternative for performing and assessing experimental PTRA in RAS

46 CFR 111.105-17 - Wiring methods for hazardous locations.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Wiring methods for hazardous locations. 111.105-17... ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-17 Wiring methods for... made with dust-tight cable entrance seals approved for the installation. [CGD 94-108, 61 FR 28284, June...

10 CFR 603.690 - Requirements for Federally-owned property.

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2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Requirements for Federally-owned property. 603.690 Section 603.690 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms Affecting Participants' Financial, Property, and Purchasing Systems Property § 603.690...

MR imaging and MR spectroscopy for characterization of cardiomyopathies in adolescents - preliminary results

International Nuclear Information System (INIS)

Beer, M.; Buchner, S.; Fuchs, J.; Machann, W.; Ritter, C.O.; Beissert, M.; Darge, K.; Hahn, D.; Koestler, H.; Wirbelauer, J.

2007-01-01

Purpose: Cardiomyopathy is a rare but life-threatening disease in children and adolescents. Recent studies reported morphological, functional or metabolic alterations of the heart. We discuss a combined MR imaging and 31 P MR spectroscopy (MRS) protocol allowing the analysis of interdependencies between these parameters. Since normal values of cardiac MR parameters in this age group are not available, we included studies of age-matched healthy adolescents. Materials and Methods: 2D-CINE was used to assess left ventricular (LV) parameters. Additional 3D-Chemical Shift Imaging (3D-CSI) and Spectral Localization with Optimal Pointspread Function (SLOOP) reconstruction allowed quantification of the cardiac energy metabolism. Patients (n = 4; all male; age 16.8 ± 2.9 years) were included on the basis of an echocardiographic diagnosis of possible cardiomyopathy. The same protocol was applied to healthy young volunteers (n = 4; 1 female, 3 male; age 15.5 ± 0.6 years). Results: The patients had a significantly higher LV mass index compared to the control group (147 ± 41 g/m2 versus 97 ± 16 g/m2; p = 0.04). The other LV parameters (including LV EF with 59 ± 22 % versus 67 ± 10 %) showed no significant differences. The phosphocreatine to adenosine triphosphate ratio (PCr/ATP-ratio) of the patients was reduced to 1.71 ± 0.40 versus 2.44 ± 0.30 (p = 0.01), combined with a tendency towards decreased PCr concentrations of 9.1 ± 2.5 versus 7.9 ± 1.0 mmol/kg. Conclusion: The combination of 31 P MR spectroscopy and MR imaging allows quantitative determination of morphologic, functional and metabolic alterations in adolescents with suspected cardiomyopathy in one examination procedure. The reduction of energy metabolism combined with unaltered global function may indicate a primary role of metabolism in the pathogenesis of cardiomyopathies in adolescents. (orig.)

25 CFR 1000.43 - May a Tribe/Consortium use its own resources to meet its self-governance planning and negotiation...

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2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false May a Tribe/Consortium use its own resources to meet its self-governance planning and negotiation expenses? 1000.43 Section 1000.43 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN...

78 FR 48182 - 60-Day Notice of Proposed Information Collection: Promise Zones

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2013-08-07

... initiative, the federal government will invest and partner with high-poverty urban, rural, and tribal... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5690-N-10] 60-Day Notice of Proposed... Officer, QDAM, Department of Housing and Urban Development, 451 7th Street SW., Room 4176, Washington, DC...

MR findings of tuberculous arthritis; significance of tuberculoma

International Nuclear Information System (INIS)

Jang, Han Won; Kim, Jeen Woo; Cho, Kil Ho

2001-01-01

To determine the magnetic resonance (MR) imaging findings of tuberculous arthritis, and the frequency-in such cases-with which tuberculoma occurs. MR images of 26 patients (M;F, 14;12: mean age, 46.2 years) with pathologically proven tuberculous arthritis were retrospectively reviewed. The presence of joint effusion, subchondral erosion, synovial proliferation and soft tissue abscess, and whether the inner wall of this abscess was smooth, were assessed. In particular, we determined whether a nodular lesion which showed low SI on T1WI, central low SI with peripheral hjigh SI on T2WI, and rim enhancement on contrast study, was a tuberculoma. The joints involved were those of the knee (n=7), hip (n=7), shoulder (n=4), sacroiliac region (n=3), elbow (n=3), and ankle (n=2). Joint effusion was noted in 15 cases (58%), and subchondral erosion in 24 (92%). synovial proliferation was found in 23 cases (88%), and soft tissue abscess in 24 (92%). The inner wall of this abscess was irregular in 17 cases (71%). A tuberculoma was present in intra-or extra-or extra-articular soft tissue in 18 cases (69%). The MR findings of tuberculous arthritis were subchondral erosion, synovial proliferation, and soft tissue abscess. The presence of a tuberculoma in intra-or extra-articular soft tissue, a specific finding in tuberculous arthritis, was noted in 69% of our cases

MR findings of tuberculous arthritis; significance of tuberculoma

Energy Technology Data Exchange (ETDEWEB)

Jang, Han Won; Kim, Jeen Woo; Cho, Kil Ho [Yeungnam Univ. College of Medicine, Taegu (Korea, Republic of)

2001-02-01

To determine the magnetic resonance (MR) imaging findings of tuberculous arthritis, and the frequency-in such cases-with which tuberculoma occurs. MR images of 26 patients (M;F, 14;12: mean age, 46.2 years) with pathologically proven tuberculous arthritis were retrospectively reviewed. The presence of joint effusion, subchondral erosion, synovial proliferation and soft tissue abscess, and whether the inner wall of this abscess was smooth, were assessed. In particular, we determined whether a nodular lesion which showed low SI on T1WI, central low SI with peripheral hjigh SI on T2WI, and rim enhancement on contrast study, was a tuberculoma. The joints involved were those of the knee (n=7), hip (n=7), shoulder (n=4), sacroiliac region (n=3), elbow (n=3), and ankle (n=2). Joint effusion was noted in 15 cases (58%), and subchondral erosion in 24 (92%). synovial proliferation was found in 23 cases (88%), and soft tissue abscess in 24 (92%). The inner wall of this abscess was irregular in 17 cases (71%). A tuberculoma was present in intra-or extra-or extra-articular soft tissue in 18 cases (69%). The MR findings of tuberculous arthritis were subchondral erosion, synovial proliferation, and soft tissue abscess. The presence of a tuberculoma in intra-or extra-articular soft tissue, a specific finding in tuberculous arthritis, was noted in 69% of our cases.

Chordoma versus chondrosarcoma of the central skull base: MR and CT findings

International Nuclear Information System (INIS)

Choi, Guk Myeong; Han, Moon Hee; Chang, Kee Hyun; Kim, Hong Dae; Yeon, Kyung Mo; Kim, Sam Soo

1998-01-01

It is known that due to both their imaging and pathologic features, the accurate differentiation of chondrosarcoma from chordoma is difficult. Through an analysis of MR and CT finding, this study aims to determine the differential points between these two tumors. In 21 patients, CT and MR imaging studies of chordoma (n=12) and chondrosarcoma (n=9) at the base of the skull were retrospectively reviewed. Diagnosis had been established by histologic examination of surgically removed specimens. Eleven of the chordomas were subclassified as conventional and one as chondroid ; eight chondrosarcoma were conventional and one was myxoid. Four chordoma patients underwent CT and MR ; in six, only MR was in one, only CT was performed. All scans were retrospectively evaluated for the location (midline/off-midline), direction of extension, margin and shape, bony destruction and calcification, MR signal intensity and enhancement patterns of the tumors. Degree of calcification was graded from I to II. Although MR and CT findings were similar in both types of tumor, location and degree of calcification may be features which usefully distinguish chordoma from chondrosarcoma. (author). 17 refs., 2 tabs., 5 figs

ESGAR consensus statement on liver MR imaging and clinical use of liver-specific contrast agents

Energy Technology Data Exchange (ETDEWEB)

Neri, E.; Boraschi, P.; Bartolozzi, C. [University of Pisa, Department of Diagnostic and Interventional Radiology, Pisa (Italy); Bali, M.A.; Matos, C. [Hopital Erasme, MRI Clinics, Department of Radiology, Bruxelles (Belgium); Ba-Ssalamah, A. [The General Hospital of the Medical University of Vienna, Department of Biomedical Imaging and Image-guided Therapy, Vienna (Austria); Brancatelli, G. [University of Palermo, Department of Radiology, Palermo (Italy); Alves, F.C. [University Hospital of Coimbra, Medical Imaging Department and Faculty of Medicine, Coimbra (Portugal); Grazioli, L. [Spedali Civili di Brescia, Department of Radiology, Brescia (Italy); Helmberger, T. [Academic Teaching Hospital of the Technical University, Department of Diagnostic and Interventional Radiology and Nuclear Medicine, Klinikum Bogenhausen, Munich (Germany); Lee, J.M. [Seoul National University College of Medicine, Division of Abdominal Imaging, Department of Radiology, Seoul (Korea, Republic of); Manfredi, R. [University of Verona, Department of Radiology, Verona (Italy); Marti-Bonmati, L. [Hospital Universitario y Politecnico La Fe, Area Clinica de Imagen Medica, Valencia (Spain); Merkle, E.M. [Universitaetsspital Basel, Klinik fuer Radiologie und Nuklearmedizin, Basel (Switzerland); Op De Beeck, B. [Antwerp University Hospital, Department of Radiology, Edegem (Belgium); Schima, W. [KH Goettlicher Heiland, Krankenhaus der Barmherzigen Schwestern and Sankt Josef-Krankenhaus, Department of Diagnostic and Interventional Radiology, Vienna (Austria); Skehan, S. [St Vincent' s University Hospital, Department of Radiology, Dublin (Ireland); Vilgrain, V. [Assistance Publique-Hopitaux de Paris, APHP, Hopital Beaujon, Radiology Department, Clichy, Paris (France); Zech, C. [Universitaetsspital Basel, Abteilungsleiter Interventionelle Radiologie, Klinik fuer Radiologie und Nuklearmedizin, Basel (Switzerland)

2016-04-15

To develop a consensus and provide updated recommendations on liver MR imaging and the clinical use of liver-specific contrast agents. The European Society of Gastrointestinal and Abdominal Radiology (ESGAR) formed a multinational European panel of experts, selected on the basis of a literature review and their leadership in the field of liver MR imaging. A modified Delphi process was adopted to draft a list of statements. Descriptive and Cronbach's statistics were used to rate levels of agreement and internal reliability of the consensus. Three Delphi rounds were conducted and 76 statements composed on MR technique (n = 17), clinical application of liver-specific contrast agents in benign, focal liver lesions (n = 7), malignant liver lesions in non-cirrhotic (n = 9) and in cirrhotic patients (n = 18), diffuse and vascular liver diseases (n = 12), and bile ducts (n = 13). The overall mean score of agreement was 4.84 (SD ±0.17). Full consensus was reached in 22 % of all statements in all working groups, with no full consensus reached on diffuse and vascular diseases. The consensus provided updated recommendations on the methodology, and clinical indications, of MRI with liver specific contrast agents in the study of liver diseases. (orig.)

French government to trim direct stake in Total

International Nuclear Information System (INIS)

Anon.

1992-01-01

This paper reports that the French government has decided to slash its direct stake in partly state owned oil company Total to 5% from 31.7%, a surprise move expected to raise 10 billion francs ($1.8 billion). At the same time, other state owned entities will be asked to boost their combined 2.2% stake in Total to 10%, leaving the government with a net 15% interest in Total vs. the current 34%. Initially, state owned insurance companies Groupe des Assurances Nationales and Assurances Generale de France will be asked to hike their stakes in Total, but others could be asked to join if needed to meet the 10% target. The government the its phase-down of participation in Total, established in 1924 to manage French interests in Iraq Petroleum Co., was prompted by the evolution of the oil context, which differs greatly from what had prompted a significant stake of the state in Total's capital

76 FR 2889 - Notice of Intent To Grant Exclusive and Co-Exclusive Patent License; NanoDynamics Life Sciences...

Science.gov (United States)

2011-01-18

... Patent License; NanoDynamics Life Sciences, Inc. AGENCY: Department of the Navy, DOD. ACTION: Notice. SUMMARY: The Department of the Navy hereby gives notice of its intent to grant to NanoDynamics Life Sciences, Inc. a revocable, nonassignable, exclusive license to practice the Government-owned inventions...

MR imaging in chronic epicondylitis humeri radialis at 1.0 T: is Gd-DTPA administration useful?

International Nuclear Information System (INIS)

Herber, S.; Kalden, P.; Kreitner, K.-F.; Thelen, M.

2001-01-01

Purpose: Evaluation of the diagnostic value and confidence of contrast-enhanced MR imaging in patients with lateral epicondylitis in comparison to clinical diagnosis. Material and Methods: 42 consecutive patients with clinically proven chronic lateral epicondylitis and 10 elbow joints of healthy controls have been examined on a 1.0 T MR-unit. Criteria for inclusion in the prospective study were: persistant pain and a failed conservative therapy. The MR protocol included STIR sequence, a native, T 2 -weighted, fat-supressed TSE sequence, and a flash-2-D sequence. Also, fat-supressed, T 1 -weighted SE sequences before and after administration of Gd-DTPA contrast media have been recorded. Results: In 39/42 patients the STIR sequence showed an increased SI of the common extensor tendom. Increased MR signal of the lateral collateral ligament combined with a thickening and a partial rupture or a full thickness tear have been observed in 15/42 cases. A bone marrow edema at the lateral epicondylus was noticed in 6 of the studied patients and a joint effusion in 18/42 patients. After administration of contrast media we noticed an average increase of SI by about 150%. However, enhanced MR imaging did not provide additional information. Conclusion: In MR imaging of chronic epicondylitis administration of gadolinium-DTPA does not provide additional information. (orig.) [de

7Li(18O, 17N8Be reaction and the 17N + 8Be-potential

Directory of Open Access Journals (Sweden)

A. T. Rudchik

2010-12-01

Full Text Available Angular distributions of the 7Li(18O, 17N8Be reaction were measured for the transitions to the ground states of 8Be and 17N and excited states of 17N at the energy Elab(18O = 114 MeV. The data were analyzed with coupled-reaction-channels method for one- and two-step transfers of nucleons and clusters. In the analysis, the 7Li + 18O potential de-duced in the analysis of the elastic 7Li + 18O-scattering data as well as shell-model spectroscopic amplitudes of trans-ferred nucleons and clusters were used. Parameters of the 8Be + 17N potential were deduced using the reaction data. Contributions of different one- and two-step transfers in the 7Li(18O, 17N8Be reaction cross-section was studied.

43 CFR 6.54 - Use or manufacture by or for the Government.

Science.gov (United States)

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Use or manufacture by or for the... REGULATIONS Licenses § 6.54 Use or manufacture by or for the Government. A license is not required with respect to the manufacture or use of any invention assigned or required to be assigned without...

Feasibility of a 2"n"d generation MR-compatible manipulator for transrectal prostate biopsy guidance

International Nuclear Information System (INIS)

Bomers, J.G.R.; Yakar, D.; Bosboom, D.G.H.; Tigelaar, G.H.; Sabisch, J.; Fuetterer, J.J.

2017-01-01

To assess the feasibility of a 2"n"d generation MR-compatible, remote-controlled manipulator (RCM) as an aid to perform MR-guided transrectal prostate biopsy in males with suspicion of prostate cancer (PCa). This prospective phase I study was approved by the local ethical committee and written informed consent was obtained from each patient. Twenty patients with ≥1 cancer suspicious region (CSR) with a PI-RADS score of ≥3 detected on the diagnostic multi-parametric MRI and no prior prostate treatment underwent MR-guided biopsy with the aid of the RCM. Complications were classified according to the modified Clavien system for reporting surgical complications. For evaluation of the workflow, procedure- and manipulation times were recorded. All CSR's (n=20) were reachable with the MR-compatible RCM and the cancer detection rate was 70 %. The median procedure time was 36:44 minutes (range, 23 - 61 minutes) and the median manipulation time for needle guide movement was 5:48 minutes (range, 1:15 - 18:35 minutes). Two Clavien grade 1 complications were reported. It is feasible and safe to perform transrectal MR-guided prostate biopsy using a MR-compatible RCM as an aid. It is a fast and efficient way to biopsy suspicious prostate lesions with a minimum number of biopsies per patient. (orig.)

MR and pathologic correlation of rabbit VX-2 carconoma

International Nuclear Information System (INIS)

Kang, H.S.; Kim, S.M.; Im, J.G.; Kim, C.W.; Han, M.C.

1991-01-01

This paper evaluates the reliability of MR imaging in tissue characterization and depiction of tumor boundaries. The authors performed MR-pathologic correlation using parosteally implanted VX-2 carcinoma in 17 rabbit thighs. T1-weighted, T2-weighted, and Gd-DTPA-enhanced T1-weighted axial images were obtained 10-20 days after tumor implantation. After the animals were killed, freezing, sectioning along the MR imaging planes, and histopathologic examination were done. For accurate MR-pathologic correlation, rabbits were fixed on the cardboard plate to minimize position change during the procedures. Tumor boundaries depicted on MR images were larger than those depicted on the specimen. Small tumors were surrounded by capsule-like, hypervascular (mainly lymphatics), loose connective tissue. Loose connective tissue became compact with tumor growth. This connective tissue showed high signal intensity on both T2-weighted and Gd-DTPA-enhanced T1-weighted images. Muscle atrophy with development of lymphatics around the tumor also contributed high signal intensity on MR images. Peritumoral edema and inflammatory reaction were not remarkable. Peritumoral lymphatics, rich connective tissue, and muscle atrophy exaggerated the size of experimentally induced malignant musculoskeletal tumors on MR images

MR imaging of cerebral palsy

International Nuclear Information System (INIS)

Saginoya, Toshiyuki; Yamaguchi, Keiichiro; Kuniyoshi, Kazuhide

1996-01-01

We evaluated 35 patients with cerebral palsy on the basis of MR imaging findings in the brain. The types of palsy were spastic quadriplegia (n=11), spastic diplegia (n=9), spastic hemiplegia (n=2), double hemiplegia (n=1), athetosis (n=10) and mixed (n=2). Of all patients, 28 (80%) generated abnormal findings. In spastic quadriplegia, although eight cases revealed severe brain damage, two cases showed no abnormal findings in the brain. One of the three had cervical cord compression caused by atlanto-axial subluxation. In spastic diplegia, the findings were divided according to whether the patient was born at term or preterm. If the patient had been born prematurely, the findings showed periventricular leukomalacia and abnormally high intensity in the posterior limbs of the internal capsule on T2-weighted images. MR imaging in spastic hemiplegia revealed cerebral infarction. In the athetoid type, half of all cases showed either no abnormal findings or slight widening of the lateral ventricle. Three cases showed abnormal signals of the basal ganglia. The reason why athetoid-type palsy did not show severe abnormality is unknown. We believe that MR imaging is a useful diagnostic modality to detect damage in the brain in cerebral palsy and plays an important role in the differentiation of cerebral palsy from the spastic palsy disease. (author)

MR imaging of cerebral palsy

Energy Technology Data Exchange (ETDEWEB)

Saginoya, Toshiyuki [Urasoe General Hospital, Okinawa (Japan); Yamaguchi, Keiichiro; Kuniyoshi, Kazuhide [and others

1996-06-01

We evaluated 35 patients with cerebral palsy on the basis of MR imaging findings in the brain. The types of palsy were spastic quadriplegia (n=11), spastic diplegia (n=9), spastic hemiplegia (n=2), double hemiplegia (n=1), athetosis (n=10) and mixed (n=2). Of all patients, 28 (80%) generated abnormal findings. In spastic quadriplegia, although eight cases revealed severe brain damage, two cases showed no abnormal findings in the brain. One of the three had cervical cord compression caused by atlanto-axial subluxation. In spastic diplegia, the findings were divided according to whether the patient was born at term or preterm. If the patient had been born prematurely, the findings showed periventricular leukomalacia and abnormally high intensity in the posterior limbs of the internal capsule on T2-weighted images. MR imaging in spastic hemiplegia revealed cerebral infarction. In the athetoid type, half of all cases showed either no abnormal findings or slight widening of the lateral ventricle. Three cases showed abnormal signals of the basal ganglia. The reason why athetoid-type palsy did not show severe abnormality is unknown. We believe that MR imaging is a useful diagnostic modality to detect damage in the brain in cerebral palsy and plays an important role in the differentiation of cerebral palsy from the spastic palsy disease. (author)

78 FR 75336 - Notice of Intent To Grant an Exclusive License; Aviation Devices and Electronic Components, L.L.C.

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2013-12-11

..., exclusive license throughout all the contracting states of the European Patent Convention, Japan, India... America in all fields of use the Government-Owned inventions described in Patent Cooperation Treaty (PCT... authorized Department of Defense Partnership Intermediary. Authority: 35 U.S.C. 207, 37 CFR Part 404. [[Page...

Build Your Own Payment Model.

Science.gov (United States)

Berlin, Joey

2017-07-01

Physicians participating in MACRA have a unique opportunity to create and submit their own alternative payment models to the government and take command of their own future payments. At least one Texas physician is taking a crack at developing his own model.

MR imaging of the central nervous system in diving-related decompression illness

International Nuclear Information System (INIS)

Reuter, M.; Hutzelmann, A.; Steffens, J.C.; Heller, M.; Fritsch, G.

1997-01-01

Purpose: This investigation was conducted to determine whether MR imaging showed cerebral or spinal damage in acute diving-related decompression illness, a term that includes decompressions sickness (DCS) and arterial gas embolism (AGE). Material and Methods: A total of 16 divers with dysbaric injuries were examined after the initiation of therapeutic recompression. Their injuries comprised: neurological DCS II n=8; AGE n=7; combined cerebral-AGE/spinal-DCS n=1. T1- and T2-weighted images of the brain were obtained in 2 planes. In addition, the spinal cord was imaged in 7 subjects. The imaging findings were correlated with the neurological symptoms. Results: MR images of the head showed ischemic cerebrovascular lesions in 6/8 patients with AGE but showed focal hyperintensities in only 2/8 divers with DCS. Spinal-cord involvement was detected in 1/7 examinations, which was the combined cerebral-AGE/spinal-DCS case. There was agreement between the locations of the documented lesions and the clinical manifestations. Conclusion: MR readily detects cerebral damage in AGE but yields low sensitivity in DCS. A negative MR investigation cannot rule out AGE or DCS. However, MR is useful in the examination of patients with decompression illness. (orig.)

Communication of 10 May 2005 received from the Government of Sweden on behalf of the participating Governments of the Nuclear Suppliers Group

International Nuclear Information System (INIS)

2005-01-01

The Director General has received a letter dated 10 May 2005 from the Government of Sweden on behalf of participating Governments of the 'Nuclear Suppliers Group (NSG).' Attached to this letter is an updated version of a paper entitled 'The Nuclear Suppliers Group: Its Origins, Role and Activities.' The original version of this paper was issued as INFCIRC/539 on 15 September 1997, and revisions were issued on 17 April 2000 and 16 September 2003. In the light of the wish expressed at the end of the letter, the revised version of the paper, attached hereto, is being circulated to Member States of the IAEA

Non-small-cell lung cancer resectability: diagnostic value of PET/MR

International Nuclear Information System (INIS)

Fraioli, Francesco; Menezes, Leon; Kayani, Irfan; Syed, Rizwan; O'Meara, Celia; Barnes, Anna; Bomanji, Jamshed B.; Punwani, Shonit; Groves, Ashley M.; Screaton, Nicholas J.; Janes, Samuel M.; Win, Thida; Zaccagna, Fulvio

2015-01-01

To assess the diagnostic performance of PET/MR in patients with non-small-cell lung cancer. Fifty consecutive consenting patients who underwent routine 18 F-FDG PET/CT for potentially radically treatable lung cancer following a staging CT scan were recruited for PET/MR imaging on the same day. Two experienced readers, unaware of the results with the other modalities, interpreted the PET/MR images independently. Discordances were resolved in consensus. PET/MR TNM staging was compared to surgical staging from thoracotomy as the reference standard in 33 patients. In the remaining 17 nonsurgical patients, TNM was determined based on histology from biopsy, imaging results (CT and PET/CT) and follow-up. ROC curve analysis was used to assess accuracy, sensitivity and specificity of the PET/MR in assessing the surgical resectability of primary tumour. The kappa statistic was used to assess interobserver agreement in the PET/MR TNM staging. Two different readers, without knowledge of the PET/MR findings, subsequently separately reviewed the PET/CT images for TNM staging. The generalized kappa statistic was used to determine intermodality agreement between PET/CT and PET/MR for TNM staging. ROC curve analysis showed that PET/MR had a specificity of 92.3 % and a sensitivity of 97.3 % in the determination of resectability with an AUC of 0.95. Interobserver agreement in PET/MR reading ranged from substantial to perfect between the two readers (Cohen's kappa 0.646 - 1) for T stage, N stage and M stage. Intermodality agreement between PET/CT and PET/MR ranged from substantial to almost perfect for T stage, N stage and M stage (Cohen's kappa 0.627 - 0.823). In lung cancer patients PET/MR appears to be a robust technique for preoperative staging. (orig.)

Leisure Time Invention

DEFF Research Database (Denmark)

Davis, Lee N.; Davis, Jerome D.; Hoisl, Karin

2013-01-01

the employee is away from the workplace. We build on existing theory in the fields of organizational creativity and knowledge recombination, especially work relating context to creativity. The paper’s main theoretical contribution is to extend our understanding of the boundaries of employee creativity......This paper studies the contextual factors that influence whether invention occurs during work time or leisure time. Leisure time invention, a potentially important but thus far largely unexplored source of employee creativity, refers to invention where the main underlying idea occurs while...... by adding to the discussion of how access to and exploitation of different types of resources—during work hours or during leisure time — may affect creativity. Based on survey data from more than 3,000 inventions from German employee inventors, we find that leisure time inventions are more frequently...

'Pop-Up' Governance: developing internal governance frameworks for consortia: the example of UK10K.

Science.gov (United States)

Kaye, Jane; Muddyman, Dawn; Smee, Carol; Kennedy, Karen; Bell, Jessica

2015-01-01

Innovations in information technologies have facilitated the development of new styles of research networks and forms of governance. This is evident in genomics where increasingly, research is carried out by large, interdisciplinary consortia focussing on a specific research endeavour. The UK10K project is an example of a human genomics consortium funded to provide insights into the genomics of rare conditions, and establish a community resource from generated sequence data. To achieve its objectives according to the agreed timetable, the UK10K project established an internal governance system to expedite the research and to deal with the complex issues that arose. The project's governance structure exemplifies a new form of network governance called 'pop-up' governance. 'Pop-up' because: it was put together quickly, existed for a specific period, was designed for a specific purpose, and was dismantled easily on project completion. In this paper, we use UK10K to describe how 'pop-up' governance works on the ground and how relational, hierarchical and contractual governance mechanisms are used in this new form of network governance.

MR angiography, MR imaging and proton MR spectroscopy in-vivo assessment of skeletal muscle ischemia in diabetic rats.

Directory of Open Access Journals (Sweden)

Stefano Delli Pizzi

Full Text Available To prospectively evaluate the feasibility of using magnetic resonance (MR techniques for in-vivo assessing a rat diabetic model of limb ischemia. Unilateral hind limb ischemia was induced by ligation of the iliac-femoral artery in male streptozotocin-treated and non-diabetic control rats. Four weeks after ligation, rats underwent MR Angiography (MRA, T(1-weighted and Short Time Inversion Recovery (STIR sequences and muscle Proton MR Spectroscopy ((1H-MRS on both hind limbs. After MR examinations, immunoblotting and immunofluorescence analysis were performed. MRA showed a signal void due to flow discontinuation distal to the artery ligation. T(1-weighted and STIR images showed, respectively, the presence of tissue swelling (p = 0.018 for non-diabetic; p = 0.027 for diabetic rats and signal hyperintensity in tissue affected by occlusion. Mean total creatine/water for the occluded limb was significantly lower than for the non-occluded limbs in both non-diabetic (5.46×10(-4 vs 1.14×10(-3, p = 0.028 and diabetic rats (1.37×10(-4 vs 1.10×10(-3; p = 0.018. MR Imaging and (1H-MRS changes were more pronounced in diabetic than in non-diabetic occluded limbs (p = 0.032. MR findings were confirmed by using histological findings. Combined MR techniques can be used to demonstrate the presence of structural and metabolic changes produced by iliac-femoral artery occlusion in rat diabetic model of limb ischemia.

WE-G-17A-05: Real-Time Catheter Localization Using An Active MR Tracker for Interstitial Brachytherapy

Energy Technology Data Exchange (ETDEWEB)

Wang, W; Damato, A; Viswanathan, A; Cormack, R [Dana Farber Cancer Institute / Brigham and Women' s Hospital, Boston, MA (United States); Harvard Medical School, Boston, MA (United States); Penzkofer, T; Schmidt, E [Brigham and Women' s Hospital, Boston, MA (United States); Pan, L; Gilson, W [Siemens Corporation, Corporate Technology, Baltimore, MD (United States); Seethamraju, R [Siemens Healthcare, Boston, MA (United States)

2014-06-15

Purpose: To develop a novel active MR-tracking system which can provide accurate and rapid localization of brachytherapy catheters, and assess its reliability and spatial accuracy in comparison to standard catheter digitization using MR images. Methods: An active MR tracker for brachytherapy was constructed by adding three printed-circuit micro-coils to the shaft of a commercial metallic stylet. A gel phantom with an embedded framework was built, into which fifteen 14-Gauge catheters were placed, following either with parallel or crossed paths. The tracker was inserted sequentially into each catheter, with MR-tracking running continuously. Tracking was also performed during the tracker's removal from each catheter. Catheter trajectories measured from the insertion and the removal procedures using the same micro-coil were compared, as well as trajectories obtained using different micro-coils. A 3D high-resolution MR image dataset of the phantom was acquired and imported into a treatment planning system (TPS) for catheter digitization. A comparison between MR-tracked positions and positions digitized from MR images by TPS was performed. Results: The MR tracking shows good consistency for varying catheter paths and for all micro-coils (mean difference ∼1.1 mm). The average distance between the MR-tracking trajectory and catheter digitization from the MR images was 1.1 mm. Ambiguity in catheter assignment from images due to crossed paths was resolved by active tracking. When tracking was interleaved with imaging, real-time images were continuously acquired at the instantaneous tip positions and displayed on an external workstation. Conclusion: The active MR tracker may be used to provide an independent measurement of catheter location in the MR environment, potentially eliminating the need for subsequent CT. It may also be used to control realtime imaging of catheter placement. This will enable MR-based brachytherapy planning of interstitial implants without

WE-G-17A-05: Real-Time Catheter Localization Using An Active MR Tracker for Interstitial Brachytherapy

International Nuclear Information System (INIS)

Wang, W; Damato, A; Viswanathan, A; Cormack, R; Penzkofer, T; Schmidt, E; Pan, L; Gilson, W; Seethamraju, R

2014-01-01

Purpose: To develop a novel active MR-tracking system which can provide accurate and rapid localization of brachytherapy catheters, and assess its reliability and spatial accuracy in comparison to standard catheter digitization using MR images. Methods: An active MR tracker for brachytherapy was constructed by adding three printed-circuit micro-coils to the shaft of a commercial metallic stylet. A gel phantom with an embedded framework was built, into which fifteen 14-Gauge catheters were placed, following either with parallel or crossed paths. The tracker was inserted sequentially into each catheter, with MR-tracking running continuously. Tracking was also performed during the tracker's removal from each catheter. Catheter trajectories measured from the insertion and the removal procedures using the same micro-coil were compared, as well as trajectories obtained using different micro-coils. A 3D high-resolution MR image dataset of the phantom was acquired and imported into a treatment planning system (TPS) for catheter digitization. A comparison between MR-tracked positions and positions digitized from MR images by TPS was performed. Results: The MR tracking shows good consistency for varying catheter paths and for all micro-coils (mean difference ∼1.1 mm). The average distance between the MR-tracking trajectory and catheter digitization from the MR images was 1.1 mm. Ambiguity in catheter assignment from images due to crossed paths was resolved by active tracking. When tracking was interleaved with imaging, real-time images were continuously acquired at the instantaneous tip positions and displayed on an external workstation. Conclusion: The active MR tracker may be used to provide an independent measurement of catheter location in the MR environment, potentially eliminating the need for subsequent CT. It may also be used to control realtime imaging of catheter placement. This will enable MR-based brachytherapy planning of interstitial implants without

Energy-Related Inventions Program: an overview of the evaluation

Energy Technology Data Exchange (ETDEWEB)

Soderstrom, E.J.; Bronfman, L.M.; Rorke, M.G.

1983-09-01

The Energy-Related Inventions Program (ERIP) is jointly administered by the US Departments of Energy and Commerce. Grants were awarded for 165 of 208 inventions recommended by the National Bureau of Standards (NBS). Of the 165 inventions, 46 have been able to acquire follow-on financing from a variety of sources. Further, 35 of the inventions have reached the marketplace, and their cumulative sales to date total $178 million. An additional 10 inventions are now starting into production. Jobs that have been created directly by production related to the inventions total 756; additional spin-off jobs attributable to the inventions include component and material suppliers, jobbers, franchisees, and distributors. The program was recently evaluated at Oak Ridge National Laboratory, with the following conclusions: (1) the evaluation process at NBS has been successful in identifying technically and economically feasible inventions, (2) the success rate for the program is about equivalent to the reported success rates of private venture capital firms, (3) the program is supporting inventions at a point in their development where they are supported by neither the venture capital community nor industry, and (4) the one-time DOE grants and the associated ERIP support to inventors have been successful in readying inventors for follow-on financing from the private sector.

MR imaging of the injured meniscus of the knee

International Nuclear Information System (INIS)

Sakai, Naotaka; Imamura, Kiyohiko; Uematsu, Koichi; Iwamura, Yuichi; Ohniwa, Hideo; Ishii, Masayoshi

1992-01-01

MR imagings (0.5 Tesla 5 mm slice, TR/TE: 510-620 msec/27-30) of the injured menisci in 38 knees of 38 patients (28 men and 10 women, with an average age of 25.9) were compared with their arthroscopic findings and classified into two types, the one with linear high-density area and the non-linear one. Menisci with longitudinal tears in 10 knees of 17 and with horizontal tears in 4 of 8 showed a linear high-density area in MRI, but the others including menisci with transverse tears (in 8 knees) or bucket-handle tears (in 7 knees) showed a non-linear high density area. These results may be due to both the angle between the tear and the slice lines of MR imaging, and the degeneration of menisci. The MRI of normal menisci in 10 knees were also investigated. A false-positive high-density area was often seen at the synovia-meniscal junction in the coronal plane of MR imaging and was seen at the posterior or anterior menisci in the saggital plane. (author)

48 CFR 1852.227-85 - Invention reporting and rights-Foreign.

Science.gov (United States)

2010-10-01

... and complete technical information concerning the invention as is necessary to enable an understanding of the nature and operation thereof. (c) The Contractor hereby grants to the Government of the United... the State in which this contract is to be performed. As to such State, Contractor hereby grants to the...

Diagnostic value of combined static-excretory MR Urography in children with hydroneph

Directory of Open Access Journals (Sweden)

Sally Emad-Eldin

2015-03-01

Full Text Available The aim of this study was to determine the feasibility, accuracy and diagnostic potential of combined static-excretory MR Urography in children with sonographically detected hydronephrosis. We prospectively evaluated 28 children (11 girls and 17 boys, mean age 8.3 years (range 2 months–16 years. Static-excretory MR Urography was performed in all cases. The results of MR Urography were compared with the results of other imaging modalities, cystoscopy and surgery. In 28 children, 61 renal units were evaluated by MR Urography (the renal unit is the kidney and its draining ureter. The final diagnoses included: normal renal units (n = 23; uretropelvic junction obstruction (n = 14; megaureter (n = 8; midureteric stricture (n = 1, complicated duplicated systems (n = 5, post ESWL non-obstructive dilation (n = 2, extrarenal pelvis (n = 4, dysplastic kidney (n = 4. Complex pathology and more than one disease entity in were found in 7 children. The MRI diagnosis correlated with the final diagnosis in 57 units, with diagnostic accuracy 93.4%. In conclusions static and excretory MRU give both morphological and functional information in a single examination without exposure to ionizing radiation and iodinated contrast agent. It is a valuable imaging technique for children with upper urinary tract dilatation; especially in cases of complex congenital pathologies and severely hydronephrotic kidney.

How James Watt invented the copier forgotten inventions of our great scientists

CERN Document Server

Schils, René

2012-01-01

Features 25 different scientists and the ideas which may not have made them famous, but made history… Typically, we remember our greatest scientists from one single invention, one new formula or one incredible breakthrough. This narrow perspective does not give justice to the versatility of many scientists who also earned a reputation in other areas of science. James Watt, for instance, is known for inventing the steam engine, yet most people do not know that he also invented the copier. Alexander Graham Bell of course invented the telephone, but only few know that he invented artificial breathing equipment, a prototype of the ‘iron lung’. Edmond Halley, whose name is associated with the comet that visits Earth every 75 years, produced the first mortality tables, used for life insurances. This entertaining book is aimed at anyone who enjoys reading about inventions and discoveries by the most creative minds. Detailed illustrations of the forgotten designs and ideas enrich the work throughout.

17 CFR 10.108 - Settlements.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Settlements. 10.108 Section 10... to the Commission; Settlements § 10.108 Settlements. (a) When offers may be made. Parties may at any time during the course of the proceeding propose offers of settlement. All offers of settlement shall...

Whole body MR in patients with multiple myeloma

International Nuclear Information System (INIS)

Piekarek, A.; Sosnowski, P.; Nowicki, A.; Komarnicki, M.

2009-01-01

Background: Multiple myeloma is a cancer of plasma cells which leads to bone marrow infiltration. Aim: Whole-body MR is the most sensitive imaging method available to detect multiple myeloma lesions. Ma terial and methods: MR scans were performed in 100 patients with multiple myeloma who were receiving treatment in the Haematology Clinic in Poznan in the years 2005 - 2006. Whole-body MR scans were performed with general coil 1.0 T in STIR sequences and T1 sequences, in coronal and sagittal planes with scanning area covering the head, neck, trunk and the limbs (FOV for specific regions was 36 -48 cm). The bone lesions were classified as focal (monofocal/multifocal lesions), infiltrative, mixed and 'salt and pepper' type. Depending on the size of the lesions the patients were included in one of three groups according to Salmon-Durie Plus classification. Results: Four main types of multiple myeloma were distinguished based on MR scans: focal (48 patients; monofocal in 10 patients), infiltrative (17 patients), mixed type (19 patients) and 'salt and pepper' type (4 patients). The remaining 12 patients had no multiple myeloma lesions in the bone marrow. Additionally, in 18% of patients a soft tissue mass could be observed. According to Salmon-Durie Plus categorisation 27 subjects were classified as having stage I, 16 patients stage and 57 patients stage III disease. In 12% of patients MR data changed the disease staging. Conclusions: WB MR is a sensitive and effective diagnostic method with an important impact on staging and further treatment of multiple myeloma. (authors)

41 CFR 102-192.10 - What authority governs this part?

Science.gov (United States)

2010-07-01

... MANAGEMENT Introduction to this Part § 102-192.10 What authority governs this part? This part is governed by... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What authority governs this part? 102-192.10 Section 102-192.10 Public Contracts and Property Management Federal Property...

MR imaging evaluation of diabetic foot

International Nuclear Information System (INIS)

Beltran, J.; Campanini, D.S.; McCalla, M.; Knight, C.T.

1988-01-01

Fourteen diabetic patients with suspected foot infection and/or neuropathic joint were evaluated with MR imaging to identify the presence and extent of infection and also to exclude coexistent infection in the neuropathic joint. Osteomyelitis (n = 8), abscess (n = 7), septic arthritis (n = 4), tenosynovitis (n = 4), and neuropathic joint (n = 5) were diagnosed with MR imaging. Osteomyelitis and/or abscess were excluded by MR findings in 13 instances. Most patients with infection had one more than one site of involvement. Clinical or surgical confirmation of the MR diagnoses was obtained in all but nine of the infection sites or cases of neuropathic joint. Only one false-negative diagnosis of osteomyelitis was made in this series. It is concluded that MR imaging provided accurate information regarding the presence and extent of infection and that this information was decisive in patient management

PET/MRI for Oncologic Brain Imaging: A Comparison of Standard MR-Based Attenuation Corrections with a Model-Based Approach for the Siemens mMR PET/MR System.

Science.gov (United States)

Rausch, Ivo; Rischka, Lucas; Ladefoged, Claes N; Furtner, Julia; Fenchel, Matthias; Hahn, Andreas; Lanzenberger, Rupert; Mayerhoefer, Marius E; Traub-Weidinger, Tatjana; Beyer, Thomas

2017-09-01

The aim of this study was to compare attenuation-correction (AC) approaches for PET/MRI in clinical neurooncology. Methods: Forty-nine PET/MRI brain scans were included: brain tumor studies using 18 F-fluoro-ethyl-tyrosine ( 18 F-FET) ( n = 31) and 68 Ga-DOTANOC ( n = 7) and studies of healthy subjects using 18 F-FDG ( n = 11). For each subject, MR-based AC maps (MR-AC) were acquired using the standard DIXON- and ultrashort echo time (UTE)-based approaches. A third MR-AC was calculated using a model-based, postprocessing approach to account for bone attenuation values (BD, noncommercial prototype software by Siemens Healthcare). As a reference, AC maps were derived from patient-specific CT images (CTref). PET data were reconstructed using standard settings after AC with all 4 AC methods. We report changes in diagnosis for all brain tumor patients and the following relative differences values (RDs [%]), with regards to AC-CTref: for 18 F-FET (A)-SUVs as well as volumes of interest (VOIs) defined by a 70% threshold of all segmented lesions and lesion-to-background ratios; for 68 Ga-DOTANOC (B)-SUVs as well as VOIs defined by a 50% threshold for all lesions and the pituitary gland; and for 18 F-FDG (C)-RD of SUVs of the whole brain and 10 anatomic regions segmented on MR images. Results: For brain tumor imaging (A and B), the standard PET-based diagnosis was not affected by any of the 3 MR-AC methods. For A, the average RDs of SUV mean were -10%, -4%, and -3% and of the VOIs 1%, 2%, and 7% for DIXON, UTE, and BD, respectively. Lesion-to-background ratios for all MR-AC methods were similar to that of CTref. For B, average RDs of SUV mean were -11%, -11%, and -3% and of the VOIs 1%, -4%, and -3%, respectively. In the case of 18 F-FDG PET/MRI (C), RDs for the whole brain were -11%, -8%, and -5% for DIXON, UTE, and BD, respectively. Conclusion: The diagnostic reading of PET/MR patients with brain tumors did not change with the chosen AC method. Quantitative accuracy of

Secret of success for invention technology

International Nuclear Information System (INIS)

Kim, Gwan Hyeong

1990-12-01

This book deals with importance, meaning, history of invention technology, technique of invention technology, and invention in connection with the duties. It covers importance, meaning, flow of invention technology development, basis of invention technology development, development, development investment, development workforce of invention technology, and development of invention technology introduction. It also contains outline, research, management of technology development information, outline, research, management of patent information, and reality of invention technology research development.

77 FR 32642 - Patents and Inventions; Delegation of Authority

Science.gov (United States)

2012-06-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Patents and... Prevention (CDC), the Deputy Director, DLPP, LSPPPO, OSELS, CDC, and the Chief, Technology Management Branch... regarding the invention and patent program of CDC and the authority to make determinations of rights in...

MR-guided MR arthrography of the shoulder

International Nuclear Information System (INIS)

Tratting, S.; Breitenseher, M.; Pretterklieber, M.; Kontaxis, G.; Rand, T.; Imhof, H.

1996-01-01

Purpose: To develop an MR-guided technique for joint puncture in MR arthrography of the shoulder and to confirm the intracapsular position of the needle tip by visualization of the flow of contrast media into the joint. Materials and methods: Three unfixed human shoulder joint specimens were examined on a 1.0 T unit. The optimal point of entrance and depth for joint puncture were estimated by means of MR-compatible markers on the skin. Needle orientation and localization of the needle tip (MR-compatible 22-gauge needle) in the shoulder joint were monitored by rapid localizer gradient-echo sequences in two orthogonal planes. To confirm the intracapsular position of the needle tip, diluted gadolinium-DTPA was administered via a long connecting tube and the flow of contrast media into the joint was viewed directly on an LCD screen using real-time MR imaging (local look technique). Results: The MR-compatible markers on the skin allowed determination of the optimal point of entrance and estimation of the depth for joint puncture. Passive visualization of the MR-compatible needle due to spin dephasing and signal loss provided adequate localization of the intra-articular needle tip position in all specimens, although significant artefacts were present on rapid localizer gradient-echo sequences with an increase in width of the apparent needle shaft. Real-time MR imaging of the flow of contrast media was possible using the local look technique and the LCD screen of the MR unit and allowed confirmation of the intracapsular position. Conclusion: MR-guided joint puncture and real-time MR-assisted contrast media application results in improved MR arthrography and may replace conventional fluoroscopic guidance. (orig.) [de

12 CFR 1710.10 - Law applicable to corporate governance.

Science.gov (United States)

2010-01-01

... AND URBAN DEVELOPMENT SAFETY AND SOUNDNESS CORPORATE GOVERNANCE Corporate Practices and Procedures § 1710.10 Law applicable to corporate governance. (a) General. The corporate governance practices and... Enterprise shall follow the corporate governance practices and procedures of the law of the jurisdiction in...

12 CFR 621.10 - Monitoring of performance categories and other property owned.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Monitoring of performance categories and other property owned. 621.10 Section 621.10 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ACCOUNTING AND REPORTING REQUIREMENTS Loan Performance and Valuation Assessment § 621.10 Monitoring of...

MR-guided lumbar sympathicolysis

Energy Technology Data Exchange (ETDEWEB)

Koenig, Claudius W.; Schott, Ulrich G.; Pereira, Philippe L.; Truebenbach, Jochen; Claussen, Claus D.; Duda, Stephan H. [Department of Diagnostic Radiology, University of Tuebingen (Germany); Schneider, Wilke [Department of Vascular Surgery, University of Tuebingen (Germany)

2002-06-01

The aim of this study was to demonstrate the feasibility of MR-guided lumbar sympathicolysis (LSL) in a non-selected patient population. One hundred one MR-guided LSL procedures were performed in 89 patients according to Haaga's technique using a horizontally open clinical MR system (0.2 T) and non-ferromagnetic 20-G cannulas (neurolysis, n=93; blockade, n=8). Only gradient-recalled sequences in either single or multislice mode [fast imaging with steady-state precession (FISP) and fast low-angle shot] were applied for anatomical survey and needle guiding. Bupivacaine injection was monitored with MR fluoroscopically. Fluid distribution was subsequently documented in a CT scan in 65 patients. Ninety-one LSL procedures could be successfully completed. Ten patients were not treated using MR due to patient inconvenience, severe motion artifacts (n=4 each), excessive spondylophytes, and retroperitoneal hematoma (n=1 each). One case of ureteral necrosis occurred. Motion artifacts were rated less severe in single-slice FISP sequences and in obese patients. An average of 3.48 sequence measurements were required for definitive needle placement. Average table time was 32.3 min. An MR-guided LSL is feasible and can be performed with acceptable safety and time effort. It can be recommended for repeated sympathetic blockades in younger patients to avoid cumulative irradiation associated with CT guidance. (orig.)

MR-guided lumbar sympathicolysis

International Nuclear Information System (INIS)

Koenig, Claudius W.; Schott, Ulrich G.; Pereira, Philippe L.; Truebenbach, Jochen; Claussen, Claus D.; Duda, Stephan H.; Schneider, Wilke

2002-01-01

The aim of this study was to demonstrate the feasibility of MR-guided lumbar sympathicolysis (LSL) in a non-selected patient population. One hundred one MR-guided LSL procedures were performed in 89 patients according to Haaga's technique using a horizontally open clinical MR system (0.2 T) and non-ferromagnetic 20-G cannulas (neurolysis, n=93; blockade, n=8). Only gradient-recalled sequences in either single or multislice mode [fast imaging with steady-state precession (FISP) and fast low-angle shot] were applied for anatomical survey and needle guiding. Bupivacaine injection was monitored with MR fluoroscopically. Fluid distribution was subsequently documented in a CT scan in 65 patients. Ninety-one LSL procedures could be successfully completed. Ten patients were not treated using MR due to patient inconvenience, severe motion artifacts (n=4 each), excessive spondylophytes, and retroperitoneal hematoma (n=1 each). One case of ureteral necrosis occurred. Motion artifacts were rated less severe in single-slice FISP sequences and in obese patients. An average of 3.48 sequence measurements were required for definitive needle placement. Average table time was 32.3 min. An MR-guided LSL is feasible and can be performed with acceptable safety and time effort. It can be recommended for repeated sympathetic blockades in younger patients to avoid cumulative irradiation associated with CT guidance. (orig.)

Nanotechnological inventions considerably improve performance characteristics

Directory of Open Access Journals (Sweden)

VLASOV Vladimir Alexeevich

2014-06-01

Full Text Available The invention «The method of production of carbon nanomaterial (RU 2509053» can be used as an additive for concretes and polymers which significantly improves their performance characteristics. The method of production of carbon nanomaterial consists of the following stages: preliminary preparation of sphagnous moss when it is refined from foreign admixtures, dried up to 10% humidity and ground, then ground material is exposed to pyrolysis under the temperature 850–950оC for 1–2 hours and cooled up to the environment temperature. After that amorphous carbon obtained in pyrolysis is treated with mechanical activation in the variable planetary mill for 7–10 hours. The invention makes it possible to provide increased outcome of nanotubes with high cleanliness. The invention «The method of production of nanodispersed metal powders and alloys of them (RU 2509626» relates to the powder metallurgy. Powder metal chloride or powder mixture at least of two metal chlorides is treated in the environment of the water steam which is supplied in reaction space at the rate of 50–100 ml/min at the temperature 400–800оC at the presence of absorbent carbon or introducing carbon oxide (II obtained during dissolution of formic acid HCOOH. The invention provides reliable production of nanodispersed metal powders and alloys of them from 3-d metal range: Ni, Co, Cu, Fe, Zn which can be used in powder metallurgy to improve baking process, in chemical industry as the fillers of polymers and reaction catalysts; as additives to anticorrosive covers, etc.

Avascular necrosis of the femoral heads: Initial screening and postoperative evaluation with MR imaging

International Nuclear Information System (INIS)

Cohen, J.M.; Weinreb, J.C.; Muschler, G.; Erdman, W.A.

1986-01-01

Fifty subjects with suspected avascular necrosis (AVN) of the femoral heads underwent MR imaging (0.35 T) of the hips in transverse and coronal planes. Studies were performed utilizing relatively T1-and T2-weighted spin-echo images. AVN was diagnosed in 42 patients (61 femurs) on the basis of decreased signal intensity in the femoral head. MR imaging was the most sensitive technique in detecting AVN when compared with plain radiography (n=31), axial CT (n=17), and technetium bone scanning (n=24). The use of T1-and T2-weighted images helped identify joint effusions and differentiate them from capsular thickening. Six subjects were restudied 6-12 months after core decompression

29 September 2015 - Vice-President of the Government of Spain S. Sáenz de Santamaría in the ATLAS visitor centre, the Synchrocyclotron, the Data Centre visit point and the LHC magnet facility with CERN Director-General R. Heuer and Technology Department Head J.M. Jiménez.

CERN Multimedia

Bennett, Sophia Elizabeth

2015-01-01

Were also present from Spain: Sra. Carmen Vela, Secretaria de Estado de Investigación, Desarrollo e Innovación, Sr. D. Bernardo de Sicart Escoda Embajador de España en Berna, Sra. Da Ana Menéndez Pérez, Embajadora Representante Permanente de España ante Naciones Unidas y OOII con sede en Ginebra, Sra. Da María Pico Directora del Gabinete de la Vicepresidenta and Sr. D. Miguel Temboury Redondo Subsecretario de Economía y Competitividad. And from CERN: Dr Maria Alandes Pradillo, Information Technology Department, Dr Maria Barroso-Lopez Deputy Group Leader, IT-PES, Dr Frédérick Bordry, Director of Accelerators and Technology, Dr Borja Fernandez Adiego Engineering Department, Prof. Maria Jose Garcia Borge ISOLDE Collaboration Spokesperson, Dr Fabiola Gianotti Director-General elect 2016-2020, Mr Frédéric Hemmer Information Technology Department Head, Prof. Mario Martinez, Spanish Scientific Delegate to CERN Council Mr Guillermo Merino Fernandez, Technology Department Mr Lluis Miralles, General Infrast...

THE PERCEPTION OF ADOPTING AN INFORMATION TECHNOLOGY INNOVATION ON RURAL BANKS OWNED BY THE LOCAL GOVERNMENT

Directory of Open Access Journals (Sweden)

Elen Puspitasari

2014-05-01

Full Text Available The performance of rural banks owned by the local government showed progress veryproud. Therefore, policies and strategies for the future development of rural banks directedin accordance with the fundamental characteristics of rural banks, which is rural banks ascommunity banks are healthy, strong, productive and spread throughout Indonesia and focusedin the provision of financial services the small, micro and medium enterprises (SME’s andlocal communities, especially in rural areas.The purpose of this study was to find out whichvariables are to be determinant to measure the user’s perceptions of adopting an informationtechnology (IT innovation on the rural banks owned by local government. Respondents in this study were employees as user’s adoption of IT on rural banks. Data obtained from respondents’ answers to the questionnaire. The factors that influence adopting an information technologyinnovation, which is voluntariness, relative advantage, compatibility, image, ease of use, resultdemonstrability, visibility, trial ability, and facilitating conditions to be determined by principlecomponent analysis under Factor Analysis Techniques.The adoption of information technologiesby individuals and organizations has been an area of substantial research to extend informationsystem. One of the important strategies that need to be done by the rural banks in order toincrease competitiveness and outreach is empowering of supporting infrastructure industriesowned by rural banks effectively, especially in information technology.

MR imaging of septic sacroiliitis

Energy Technology Data Exchange (ETDEWEB)

Stuerzenbecher, A.; Hamm, B.; Bollow, M. [Humboldt-Universitaet, Berlin (DD). Bereich Medizin (Charite); Braun, J. [Freie Univ. Berlin (Germany). Universitaetsklinikum Benjamin Franklin; Paris, S. [Unfallkrankenhaus Berlin (Germany). Dept. of Radiology; Biedermann, T. [Krankenhaus Berlin-Buch (Germany). II. Kinderklinik

2000-08-01

Objective. To investigate the diagnostic value of magnetic resonance (MR) imaging in detecting septic sacroiliitis and to determine whether the MR characteristics allow this entity to be differentiated from sacroiliitis in spondylarthropathy (SpA).Patients and design. The imaging findings of 11 patients with septic sacroiliitis were retrospectively analyzed by two experienced radiologists. Radiographic surveys of the pelvis as well as computed tomography (CT) and MR images of the sacroiliac joints were available in all cases. Seven of the patients additionally underwent a follow-up MR examination. The MR imaging protocol comprised combinations of coronal and transverse T1-weighted spin-echo (SE) or fast SE sequences, T2-weighted gradient-echo (GE) sequences and short tau inversion recovery sequence (STIR) sequences as well as dynamic contrast- enhanced T1-weighted acquisitions.Results. Three patients with a short disease history showed anterior and/or posterior subperiosteal infiltrations (''lava cleft phenomenon''), transcapsular infiltrations of juxta-articular muscle layers, which obscured the fasciae, and periarticular bone marrow edema. The eight patients with more advanced stages of sacroiliitis additionally showed abscess formation, sequestration, and erosion. At follow-up MR examination (n=7) under systemic antibiotic treatment, the morphologic characteristics showed progression (n=1), regression (n=4), unchanged findings (n=1), or a mixed response (n=1). Clinical improvement precedes resolution of the MR findings.Conclusions. Anterior and/or posterior subperiosteal infiltrations and transcapsular infiltrations of juxta-articular muscle layers were depicted in all patients. These MR imaging findings are characteristic of septic sacroiliitis and may be used to differentiate this entity from sacroiliitis in SpA. (orig.)

A novel photoaffinity ligand for the phencyclidine site of the N-methyl-D-aspartate receptor labels a Mr 120,000 polypeptide

International Nuclear Information System (INIS)

Sonders, M.S.; Barmettler, P.; Lee, J.A.; Kitahara, Y.; Keana, J.F.; Weber, E.

1990-01-01

A radiolabeled photoaffinity ligand has been developed for the N-methyl-D-aspartate (NMDA)-preferring excitatory amino acid receptor complex. [3H]3-Azido-(5S, 10R)(+)-5-methyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine [3H]3-azido-MK-801 demonstrated nearly identical affinity, density of binding sites, selectivity, pH sensitivity, and pharmacological profile in reversible binding assays with guinea pig brain homogenates to those displayed by its parent compound, MK-801. When employed in a photo-labeling protocol designed to optimize specific incorporation, [3H]3-azido-MK-801 labeled a single protein band which migrated in sodium dodecyl sulfate-polyacrylamide gels with Mr = 120,000. Incorporation of tritium into this band was completely inhibited when homogenates and [3H]3-azido-MK-801 were coincubated with 10 microM phencyclidine. These data suggest that the phencyclidine site of the NMDA receptor complex is at least in part comprised of a Mr = 120,000 polypeptide

L’invention instrumentale

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Jacques Dewitte

2011-03-01

Full Text Available L’instrument de musique n’a pas d’identité déterminée avant qu’il ne soit joué par un musicien concret, ou utilisé dans une œuvre singulière. Pour Stravinsky, l’instrument de musique « n’est rien en soi ». C’est l’œuvre, comme invention et création, qui donne à l’instrument son identité, sur la base de propriétés organologiques préexistantes. Les œuvres de Stravinsky pour petite formation illustrent cette idée d’une invention de l’instrument de musique par l’œuvre qu’il joue, ainsi que son amour pour des instruments nouveaux ou « nouveaux pour lui » (le cymbalum. L’invention instrumentale (qui n’est pas ici création d’un nouvel instrument consiste à faire sonner de manière neuve un instrument déjà existant. Cette invention suppose une « érotique » musicale, un amour spécifique pour les instruments et les altérités dont ils sont porteurs. Tout se passe alors comme si un a priori (une possibilité musicale enfouie dans l’instrumentA musical instrument has no specific identity until it is played by a concrete musician or used in a singular work. According to Stravinsky, a musical instrument is « nothing in itself ». Only a work, as a process of invention and creation, gives an instrument its identity on the basis of pre-existing organologic properties. Stravinsky’s works for small ensembles show how musical instruments may be invented by the work which they play, as well as the composer’s love for instruments that are new or “new for him” (such as the cymbalo. Musical invention (which does not mean here the creation of a new instrument consists in giving a new ring to an existing instrument. This kind of invention implies a notion of musical “eroticism”, that is a specific love for instruments and the otherness they may bear. Everything is happening as though an a priori quality (a musical possibility buried in the instrument appeared only a posteriori

Intrahepatic and hilar mass-forming cholangiocarcinoma: Qualitative and quantitative evaluation with diffusion-weighted MR imaging

Energy Technology Data Exchange (ETDEWEB)

Fattach, Hassan El, E-mail: hassangreenmed@gmail.com [Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris (France); Dohan, Anthony, E-mail: anthony.dohan@lrb.aphp.fr [Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris (France); Université Paris-Diderot, Sorbonne Paris Cité, 10 Avenue de Verdun, 75010 Paris (France); UMR INSERM 965-Paris 7 “Angiogenèse et recherche translationnelle”, 2 rue Amboise Paré, 75010 Paris (France); Guerrache, Youcef, E-mail: docyoucef05@yahoo.fr [Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris (France); Dautry, Raphael, E-mail: raphael.dautry@lrb.aphp.fr [Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris (France); Université Paris-Diderot, Sorbonne Paris Cité, 10 Avenue de Verdun, 75010 Paris (France); and others

2015-08-15

Highlights: • DW-MR imaging helps depicts all intrahepatic or hilar mass-forming cholangiocarcinomas. • DW-MRI provides best conspicuity of intrahepatic or hilar mass-forming cholangiocarcinomas than the other MRI sequences (P < 0.001). • The use of normalized ADC using the liver as reference organ results in the most restricted distribution of ADC values of intrahepatic or hilar mass-forming cholangiocarcinomas (variation coefficient = 16.6%). - Abstract: Objective: To qualitatively and quantitatively analyze the presentation of intrahepatic and hilar mass-forming cholangiocarcinoma with diffusion-weighted magnetic resonance imaging (DW-MRI). Materials and methods: Twenty-eight patients with histopathologically proven mass-forming cholangiocarcinoma (hilar, n = 17; intrahepatic, n = 11) underwent hepatic DW-MRI at 1.5-T using free-breathing acquisition and three b-values (0,400,800 s/mm{sup 2}). Cholangiocarcinomas were evaluated qualitatively using visual analysis of DW-MR images and quantitatively with conventional ADC and normalized ADC measurements using liver and spleen as reference organs. Results: All cholangiocarcinomas (28/28; 100%) were visible on DW-MR images. DW-MRI yielded best conspicuity of cholangiocarcinomas than the other MRI sequences (P < 0.001). Seven cholangiocarcinomas (7/11; 64%) showed hypointense central area on DW-MR images. Conventional ADC value of cholangiocarcinomas (1.042 × 10{sup −3} mm{sup 2}/s ± 0.221 × 10{sup −3} mm{sup 2}/s; range: 0.616 × 10{sup −3} mm{sup 2}/s to 2.050 × 10{sup −3} mm{sup 2}/s) was significantly lower than that of apparently normal hepatic parenchyma (1.362 × 10{sup −3} mm{sup 2}/s ± 0.187 × 10{sup −3} mm{sup 2}/s) (P < 0.0001), although substantial overlap was found. No significant differences in ADC and normalized ADC values were found between intrahepatic and hilar cholangiocarcinomas. The use of normalized ADC using the liver as reference organ resulted in the most restricted

Intrahepatic and hilar mass-forming cholangiocarcinoma: Qualitative and quantitative evaluation with diffusion-weighted MR imaging

International Nuclear Information System (INIS)

Fattach, Hassan El; Dohan, Anthony; Guerrache, Youcef; Dautry, Raphael

2015-01-01

Highlights: • DW-MR imaging helps depicts all intrahepatic or hilar mass-forming cholangiocarcinomas. • DW-MRI provides best conspicuity of intrahepatic or hilar mass-forming cholangiocarcinomas than the other MRI sequences (P < 0.001). • The use of normalized ADC using the liver as reference organ results in the most restricted distribution of ADC values of intrahepatic or hilar mass-forming cholangiocarcinomas (variation coefficient = 16.6%). - Abstract: Objective: To qualitatively and quantitatively analyze the presentation of intrahepatic and hilar mass-forming cholangiocarcinoma with diffusion-weighted magnetic resonance imaging (DW-MRI). Materials and methods: Twenty-eight patients with histopathologically proven mass-forming cholangiocarcinoma (hilar, n = 17; intrahepatic, n = 11) underwent hepatic DW-MRI at 1.5-T using free-breathing acquisition and three b-values (0,400,800 s/mm 2 ). Cholangiocarcinomas were evaluated qualitatively using visual analysis of DW-MR images and quantitatively with conventional ADC and normalized ADC measurements using liver and spleen as reference organs. Results: All cholangiocarcinomas (28/28; 100%) were visible on DW-MR images. DW-MRI yielded best conspicuity of cholangiocarcinomas than the other MRI sequences (P < 0.001). Seven cholangiocarcinomas (7/11; 64%) showed hypointense central area on DW-MR images. Conventional ADC value of cholangiocarcinomas (1.042 × 10 −3 mm 2 /s ± 0.221 × 10 −3 mm 2 /s; range: 0.616 × 10 −3 mm 2 /s to 2.050 × 10 −3 mm 2 /s) was significantly lower than that of apparently normal hepatic parenchyma (1.362 × 10 −3 mm 2 /s ± 0.187 × 10 −3 mm 2 /s) (P < 0.0001), although substantial overlap was found. No significant differences in ADC and normalized ADC values were found between intrahepatic and hilar cholangiocarcinomas. The use of normalized ADC using the liver as reference organ resulted in the most restricted distribution of ADC values of cholangiocarcinomas (variation

Pathological Corporate Governance Deficiencies in South Africa's State-Owned Companies: A Critical Reflection

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Tebello

2018-01-01

Full Text Available Globally, states use state-owned companies (SOCs or public corporations to provide public goods, limit private and foreign control of the domestic economy, generate public funds for the fiscus, increase service delivery and encourage economic development and industrialisation. Particularly given its unique socio-political and economic dynamics, a country such as South Africa clearly needs this type of strategic enterprise. Yet, that does not mean that everything at our SOCs is as it should be. The beleaguered South African Broadcasting Corporation (SABC has recently seen the resignation of board members, shareholder interference in its operational affairs, and a high turnover of chief accounting officers and other executive management members. Due to non-performance, it has also received several cash injections from its shareholder to enable it to continue to deliver its services. In addition, the shareholder minister took it upon herself to amend the SABC's memorandum of incorporation, conferring upon herself the authority to appoint, suspend or even dismiss key executive members. South African Airways (SAA, in turn, has had seven CEOs in less than four years, has had to be bailed out at a cost of R550 million, and has in addition been granted a R5 billion guarantee by the shareholder for a restructuring exercise. Other SOCs such as Eskom, the Post Office and Telkom have also experienced high board and executive management turnover, perennial underperformance necessitating regular bailouts, and challenges regarding the division of power between their boards and the various shareholder ministers. Another issue that seems to plague South Africa's SOCs is the appointment of board members and executive officials with questionable qualifications. By critically examining the corporate governance challenges besetting the SABC, SAA and Eskom in particular, this article seeks to explore the root causes of the corporate governance deficiencies of SOCs

Non-Intentional Invention: The Promethean, Trickster, and Improvisational Invention Heuristics of Academic Writers and Poets

Science.gov (United States)

Wirtz, Jason

2013-01-01

This essay introduces a novel way to conceptualize writerly invention -- invention as adopting a non-intentional intellectual stance wherein heuristics are experienced as acting upon the writer as opposed to being enacted by the writer. This view of invention complicates and extends the traditional, Aristotelian view of invention as discreet…

75 FR 40819 - Records Governing Off-the-Record Communications; Public Notice

Science.gov (United States)

2010-07-14

...-24-10 Lee Emery.\\1\\ 2. P-739-000 6-15-10 Kristen Murphy.\\2\\ 3. P-2621-009 6-24-10 Alicia M. Rowe. 4... regarding Natural Dam hydroelectric project. Kimberly D. Bose, Secretary. [FR Doc. 2010-17098 Filed 7-13-10...

The use of MR in cardiological diagnostics

International Nuclear Information System (INIS)

Smith, Hans-Joergen

2004-01-01

Image diagnostics is playing an important role in cardiology, and magnetic resonance tomography (MR) is one of many methods used in examinations of the heart. Based on studies of the literature and his own experience the author surveys the potential of MR in today's and tomorrow's diagnostics of heart diseases. Among the image diagnostic methods MR is the one that can give the most extensive information about the heart's anatomy and function. In a non-invasive way and without the use of ionizing radiation, MR can represent the anatomy in selectable planes, visualize and quantify the heart's pumping function and functioning of the cardiac valves, and give detailed information about the regional contractility, blood flow and viability of myocard. MR is capable of giving important and to some extent unique contributions to heart diseases, both congenital and contracted heart disease. Because of failing availability and competence MR is still little used in cardiological diagnostics, but the method undoubtedly has the potential to play a very important role in the future

Proton MR spectroscopy in patients with acute temporal lobe seizures.

Science.gov (United States)

Castillo, M; Smith, J K; Kwock, L

2001-01-01

Decreases in N-acetyl aspartate (NAA) as seen by proton MR spectroscopy are found in hippocampal sclerosis, and elevated levels of lipids/lactate have been observed after electroconvulsive therapy. Our purpose was to determine whether increased levels of lipids/lactate are found in patients with acute seizures of hippocampal origin. Seventeen patients with known temporal lobe epilepsy underwent proton MR spectroscopy of the mesial temporal lobes within 24 hours of their last seizure. Four of them were restudied when they were seizure-free. Five healthy individuals were used as control subjects. All MR spectroscopy studies were obtained using a single-voxel technique with TEs of 135 and 270. The relationship between the presence of lipids/lactate and seizures was tested using Fisher's exact test. Mean and standard deviations for NAA/creatine (Cr) were obtained in the hippocampi in patients with seizures on initial and follow-up studies and these values were compared with those in the control subjects. Seizure lateralization was obtained in 15 patients. Of the 17 seizure locations that involved hippocampi, 16 showed lipids/lactate by proton MR spectroscopy. Of the 13 hippocampi not directly affected by seizures, 10 showed no lipids/lactate and three showed lipids/lactate. The relationship between lipids/lactate and seizure location was confirmed. A comparison of NAA/Cr ratios for the involved hippocampi with those in control subjects showed significant differences on initial MR spectroscopy; however, no significant difference was found between acute and follow-up NAA/Cr ratios in hippocampi affected by seizures. Lipids/lactate were present in the hippocampi of patients with acute seizures and decreased when the patients were seizure-free. Thus, lipids/lactate may be a sensitive marker for acute temporal lobe seizures.

Transport, monitoring, and successful brain MR imaging in unsedated neonates

International Nuclear Information System (INIS)

Mathur, Amit M.; Neil, Jeffrey J.; McKinstry, Robert C.; Inder, Terrie E.

2008-01-01

Neonatal cerebral MR imaging is a sensitive technique for evaluating brain injury in the term and preterm infant. In term encephalopathic infants, MR imaging reliably detects not only the pattern of brain injury but might also provide clues about the timing of injury. In premature infants, MR imaging has surpassed US in the detection of white matter injury, a common lesion in this population. Concerns remain about the safety and transport of sedated neonates for MR examination to radiology suites, which are usually located at a distance from neonatal intensive care units. We present our own institutional experience and guidelines used to optimize the performance of cerebral MR examinations in neonates without sedation or anesthesia. (orig.)

39 CFR 230.10 - What do these rules govern?

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false What do these rules govern? 230.10 Section 230.10 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION OFFICE OF INSPECTOR GENERAL Rules Governing Compliance With Subpoenas, Summonses, and Court Orders by Postal Employees Within the...

Unsteady flow damping force prediction of MR dampers subjected to sinusoidal loading

Science.gov (United States)

Yu, M.; Wang, S. Q.; Fu, J.; Peng, Y. X.

2013-02-01

So far quasi-steady models are usually used to design magnetorheological (MR) dampers, but these models are not sufficient to describe the MR damper behavior under unsteady dynamic loading, for fluid inertia is neglected in quasi-steady models, which will bring more error between computer simulation and experimental results. Under unsteady flow model, the fluid inertia terms will bring error calculated upto 10%, so it is necessary to be considered in the governing equation. In this paper, force-stroke behavior of MR damper with flow mode due to sinusoidal loading excitation is mainly investigated, to simplify the analysis, the one-dimensional axisymmetric annular duct geometry of MR dampers is approximated as a rectangular duct. The rectangular duct can be divided into 3 regions for the velocity profile of the incompressible MR fluid flow, in each region, a partial differential equation is composed of by Navier-Stokes equations, boundary conditions and initial conditions to determine the velocity solution. In addition, in this work, not only Bingham plastic model but the Herschel—Bulkley model is adopted to analyze the MR damper performance. The damping force resulting from the pressure drop of unsteady MR dampers can be obtained and used to design or size MR dampers. Compared with the quasi-steady flow damping force, the damping force of unsteady MR dampers is more close to practice, particularly for the high-speed unsteady movement of MR dampers.

Unsteady flow damping force prediction of MR dampers subjected to sinusoidal loading

International Nuclear Information System (INIS)

Yu, M; Fu, J; Wang, S Q; Peng, Y X

2013-01-01

So far quasi-steady models are usually used to design magnetorheological (MR) dampers, but these models are not sufficient to describe the MR damper behavior under unsteady dynamic loading, for fluid inertia is neglected in quasi-steady models, which will bring more error between computer simulation and experimental results. Under unsteady flow model, the fluid inertia terms will bring error calculated upto 10%, so it is necessary to be considered in the governing equation. In this paper, force-stroke behavior of MR damper with flow mode due to sinusoidal loading excitation is mainly investigated, to simplify the analysis, the one-dimensional axisymmetric annular duct geometry of MR dampers is approximated as a rectangular duct. The rectangular duct can be divided into 3 regions for the velocity profile of the incompressible MR fluid flow, in each region, a partial differential equation is composed of by Navier-Stokes equations, boundary conditions and initial conditions to determine the velocity solution. In addition, in this work, not only Bingham plastic model but the Herschel—Bulkley model is adopted to analyze the MR damper performance. The damping force resulting from the pressure drop of unsteady MR dampers can be obtained and used to design or size MR dampers. Compared with the quasi-steady flow damping force, the damping force of unsteady MR dampers is more close to practice, particularly for the high-speed unsteady movement of MR dampers.

Cervicofacial tissue infarction in patients with acute invasive fungal sinusitis: prevalence and characteristic MR imaging findings.

Science.gov (United States)

Seo, Jungmin; Kim, Hyung-Jin; Chung, Seung-Kyu; Kim, Eunhee; Lee, Hanbee; Choi, Jin Wook; Cha, Ji Hoon; Kim, Hye Jung; Kim, Sung Tae

2013-03-01

Tissue infarction is known as one of the characteristic features of invasive fungal sinusitis (IFS). The purpose of this study was to investigate the prevalence and characteristic MR imaging findings of cervicofacial tissue infarction (CFTI) associated with acute IFS. We retrospectively reviewed MR images in 23 patients with histologically or microbiologically proven acute IFS. CFTI was defined as an area of lack of enhancement in and around the sinonasal tract on contrast-enhanced T1-weighted images. We divided CFTI into two groups, i.e., intrasinonasal and extrasinonasal. Particular attention was paid to the location of extrasinonasal CFTI and the signal intensity of CFTI on T1- and T2-weighted images. The presence of bone destruction on CT scans was also recorded. CFTI was found in 17 (74%) of 23 patients. All of these 17 patients had intrasinonasal CFTI, and 13 patients also had extrasinonasal CFTI. All 13 patients with extrasinonasal CFTI died of disease directly related to IFS. Various locations were involved in the 13 patients with extrasinonasal CFTI, including the orbit (n = 8), infratemporal fossa (n = 7), intracranial cavity (n = 3), and oral cavity and/or facial soft tissue (n = 4). Various signal intensities were noted at the area of CFTI on T1- and T2-weighted images. Bone destruction was found on CT scans in only 3 of 17 patients with CFTI. CFTI with preservation of the bony wall of the involved sinonasal tract may be a characteristic MR imaging finding of acute IFS. The mortality is very high once the lesion extends beyond the sinonasal tract.

Appearance of abdominal wall endometriosis on MR imaging

International Nuclear Information System (INIS)

Busard, Milou P.H.; Kuijk, Cees van; Waesberghe, Jan Hein T.M. van; Mijatovic, Velja; Hompes, Peter G.A.

2010-01-01

Abdominal wall endometriosis (AWE) is defined as endometrial tissue that is superficial to the peritoneum. AWE is often difficult to diagnose, mimicking a broad spectrum of diseases. The aim of this study was to describe the appearance of AWE on magnetic resonance (MR) imaging. We present ten patients with AWE (12 lesions) in which MR imaging was used for diagnosis. MR imaging included T2-weighted imaging and T1-weighted imaging with fat suppression. To assess the value of diffusion-weighted imaging (DWI) in endometriosis, four patients underwent additional DWI. The apparent diffusion coefficient (ADC) was calculated using b values of 50, 400, 800 and 1,200 s/mm 2 . In most cases, the lesion was located ventral or dorsal to the aponeurosis of the rectus oblique muscle (n=6) or in the rectus abdominis (n = 5). MR of AWE lesions showed isointense or slightly hyperintense signal compared with muscle on T2-weighted images and showed isointense or slightly hyperintense signal compared with muscle on T1-weighted images with foci of high signal intensity, indicative of haemorrhage. The mean ADC value of AWE was 0.93 x 10 -3 /mm 2 /s. MR imaging seems to be useful in determining the location and depth of infiltration in surrounding tissue preoperatively. (orig.)

Chondrosarcoma : MR imaging findings correlated with pathologic classification and grade

International Nuclear Information System (INIS)

Cho, Seong Whi; Kang, Heung Sik; Kim, Sam Soo; Lee, Sang Hyun; Cho, Jeong Yeon; Yeon, Kyung Mo

1996-01-01

To evaluate the MR imaging findings of chondrosarcomas by correlation with pathologic classification and grade. We performed MR imaging-pathologic correlation of nineteen chondrosarcomas. Conventional chondrosarcomas accounted for 15 cases (grade I:6, II:6, III:3) and the mesenchymal and dedifferentiated types each accounted for two. MR signal intensity (SI) of the tumor on T1- and T2-weighted images (T1WI and T2WI, respectively), was classified as homogeneous or heterogeneous low-, iso- or high SI, and enhancing pattern as marginal, marginal and septal, marginal and nodular, or diffuse enhancement. Eighteen cases of chondrosarcomas (95%) showed homogeneous or heterogeneous low- or iso SI on T1WI and high SI on T2WI. Low grade conventional chondrosarcomas showed marginal and septal (n=8/10) or marginal (n=2/10) enhancement on Gd-enhanced MR images. Grade III conventional chondrosarcomas showed marginal or marginal and nodular enhancement. Dedifferentiated and mesenchymal chondrosarcomas showed marginal and nodular or diffuse enhancement. Chondrosarcomas showed iso- or low SI on T1WI and high SI on T2WI. Marginal and septal enhancement was demonstrated on Gd-enhanced MR images of grade I and II conventional chondrosarcomas. If a tumor showed a marginal and nodular or diffuse enhancing pattern, this suggested it was a of high grade chondrosarcoma

Measurement of N and C diffusion in Sm2Fe17 by magnetic relaxation

International Nuclear Information System (INIS)

Mommer, N.; Hirscher, M.; Gerlach, M.; Van Lier, J.; Kronmueller, H.; Kubis, M.; Mueller, K.-H.

1998-01-01

Magnetic after-effect (MAE) measurements of nitrided and carburized Sm 2 Fe 17 compounds were performed in the temperature range of 140 K to 480 K. Both nitrided and carburized compounds show relaxation maxima at 285 and 300 K, respectively, which are absent in pure Sm 2 Fe 17 compounds. Therefore, these relaxation maxima are attributed to jumps of interstitially dissolved nitrogen or carbon atoms. Numerical evaluation yielded an activation enthalpy Q N (0.84±0.05) eV and a pre-exponential factor τ 0 N =3.10 -15±1 s for the short-range diffusion of N atoms. The corresponding values for the carbon diffusion are Q C =(0.91±0.05) eV and τ 0 C =1.10 -15±1 s. The carbon and nitrogen content of the samples was determined from the increase in mass during nitrogenation or carburization to Sm 2 Fe 17 N 1.2 and Sm 2 Fe 17 C 2.6 . (orig.)

Usefulness of MR imaging in pathologic fracture of long bone

International Nuclear Information System (INIS)

Lim, Hyo Soon; Park, Jin Gyoon; Song, Jae Min; Chung, Tae Woong; Yoon, Woong; Kang, Heoung Kyun

2002-01-01

The purpose of this study was to evaluate the usefulness of MR imaging of pathologic fractures of the long bones. In 18 patients aged between four and 75 (mean, 25.8) years with histologically confirmed pathologic fractures of the long bones, plain radiographs and MR images were retrospectively analyzed. The former were examined with regard to location and type of fracture, and the presence or absence of underlying disease causing fracture; and the latter in terms of underlying disease, extraosseous mass formation, and soft tissue change. The long bones involved were the femur in nine patients, the humerus in six, and the tibia in three. Underlying diseases were metastatic tumor (n=6), benign bone tumor (n=5), primary malignant bone tumor (n=4), osteomyelitis (n=2), and eosinophilic granuloma (n=1). Plain radiographs showed the fracture site as the metaphysis in ten cases, the disphysis in five, and the metadisphysis in one. Fractures were either transverse (n=10), oblique (n=3), spiral (n=1), vertical (n=1), or telescopic (n=1). In two cases, the fracture line was not visible. MR images revealed underlying diseases in all cases. Two benign bone tumors took the form of a cystic mass, hematoma was seen in three cases. Where pathologic fracture of a long bone had occurred, or a pathologic fracture in which the findings of plain radiography were equivocal, MR imaging was useful for evaluating the pattern and extent of an underlying lesion

Pediatric blunt cerebrovascular injury: the McGovern screening score.

Science.gov (United States)

Herbert, Joseph P; Venkataraman, Sidish S; Turkmani, Ali H; Zhu, Liang; Kerr, Marcia L; Patel, Rajan P; Ugalde, Irma T; Fletcher, Stephen A; Sandberg, David I; Cox, Charles S; Kitagawa, Ryan S; Day, Arthur L; Shah, Manish N

2018-03-16

OBJECTIVE The objective of this study was to assess the incidence, diagnosis, and treatment of pediatric blunt cerebrovascular injury (BCVI) at a busy Level 1 trauma center and to develop a tool for accurately predicting pediatric BCVI and the need for diagnostic testing. METHODS This is a retrospective cohort study of a prospectively collected database of pediatric patients who had sustained blunt trauma (patient age range 0-15 years) and were treated at a Level 1 trauma center between 2005 and 2015. Digital subtraction angiography, MR angiography, or CT angiography was used to confirm BCVI. Recently, the Utah score has emerged as a screening tool specifically targeted toward evaluating BCVI risk in the pediatric population. Using logistical regression and adding mechanism of injury as a logit, the McGovern score was able to use the Utah score as a starting point to create a more sensitive screening tool to identify which pediatric trauma patients should receive angiographic imaging due to a high risk for BCVI. RESULTS A total of 12,614 patients (mean age 6.6 years) were admitted with blunt trauma and prospectively registered in the trauma database. Of these, 460 (3.6%) patients underwent angiography after blunt trauma: 295 (64.1%), 107 (23.3%), 6 (1.3%), and 52 (11.3%) patients underwent CT angiography, MR angiography, digital subtraction angiography, and a combination of imaging modalities, respectively. The BCVI incidence (n = 21; 0.17%) was lower than that in a comparable adult group (p tools for BCVI, misclassified 6 (28.6%), 6 (28.6%), 7 (33.3%), and 10 (47.6%) patients with BCVI, respectively, as "low risk" and not in need of subsequent angiographic imaging. By incorporating the mechanism of injury into the score, the McGovern score only misclassified 4 (19.0%) children, all of whom were managed conservatively with no treatment or aspirin. CONCLUSIONS With a low incidence of pediatric BCVI and a nonsurgical treatment paradigm, a more conservative approach

Evaluation of the pedal artery: comparison of three-dimensional gadolinium-enhanced MR angiography with digital subtraction angiography

Energy Technology Data Exchange (ETDEWEB)

Lee, Jeong Min; Kang, Sung Gwon; Byun, Joo Nam; Kim, Young Cheol; Choi, Jeong Yeol; Kim, Dong Hyun [College of Medicine, Chosun Univ., Kwangju (Korea, Republic of)

2002-07-01

To compare the three-dimensional gadolinium-enhanced MR angiography with digital subtraction angiography (DSA) for evaluation of the pedal artery. In 12 extremities of 11 patients, both digital subtraction angiography (DSA) and contrast-enhanced MR angiography (CE-MR angiography) were performed during the same week. Among ten of the 11 patients, the following conditions were present: atherosclerosis (n=4), diabetic foot (n=3), Buerger's disease (n=1), calciphylactic arteriopathy (n=1) and arteriovenous malformation of the foot (n=1). The remaining patient underwent angiography prior to flap surgery. For MR angiography, a 1.5T system using an extremity or head coil was used. A three-dimensional FISP (fast imaging with steady state precession) sequence was obtained before enhancement, followed by four sequential acquisitions (scan time, 20 secs, scan interval time, 10 secs) 10 seconds after intravenous bolus injection of normal saline (total 10 cc), following intravenous administration of gadolinium (0.02 mmol/kg, 3 ml/sec). Arterial segments of the ankle and foot were classified as the anterior or posterior tibial artery, the distal peroneal artery, the medial or lateral plantar artery, the pedal arch, and the dorsalis pedis artery. Two radiologists independently analysed visualization of each arteraial segment and the mean of visible arterial segments in one extreminty using CE-MR angiography and DSA. Among 84 arterial segments, 16 were invisible at both CE-MR angiography and DSA, while 39 were demonstrated by both modalities. Twenty-six segments were visible only at CE-MR angiography and three only at DSA. CE-MR angiography displayed a higher number of arterial segments than DSA (mean, 5.42 vs. mean 3.50, respectively), a difference which was statistically significant (p<0.000). The difference between each arterial segment was not statistically significant, except for the dorsalis pedis artery (t test, p<0.000). In that it provides additional information for

17 CFR 270.3a-3 - Certain investment companies owned by companies which are not investment companies.

Science.gov (United States)

2010-04-01

... the definition of the term “investment company” by section 3(b)(1) or 3(b)(2) of the Act (15 U.S.C... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Certain investment companies owned by companies which are not investment companies. 270.3a-3 Section 270.3a-3 Commodity and...

17 CFR 242.201 - Price test.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Price test. 242.201 Section...-Regulation of Short Sales § 242.201 Price test. Link to an amendment published at 75 FR 11323, Mar. 10, 2010. (a) No short sale price test, including any short sale price test of any self-regulatory organization...

Invention/Re-invention

OpenAIRE

Mera, M.

2009-01-01

This article examines the relationship between texts that are re-invented for different media and/or contexts including: film remakes, prequels and sequels, video games that become films and vice versa, internet mashups, and television series that move across geographical borders. The article points to significant sources in this emerging field and presents some of the challenges that arise in relation to its study. In particular questions of originality, fidelity, repetition and difference a...

Re-Inventing Shared Governance: Implications for Organisational Culture and Institutional Leadership

Science.gov (United States)

Stensaker, Bjorn; Vabo, Agnete

2013-01-01

Shared governance has been a key historical characteristic of higher education although this form of governance has come under increased pressure in recent decades. It is often argued that shared governance is less relevant for tackling the challenges related to a more dynamic environment of the sector. This paper discusses underlying premises for…

MR and CT imaging of pulmonary valved conduits in children and adolescents: normal appearance and complications

Energy Technology Data Exchange (ETDEWEB)

Tenisch, Estelle V.; Alamo, Leonor T.; Gudinchet, Francois [Lausanne University Hospital, Department of Medical Imaging, Lausanne (Switzerland); Sekarski, Nicole [Lausanne University Hospital, Department of Pediatrics, Lausanne (Switzerland); Hurni, Michel [Lausanne University Hospital, Department of Cardiovascular Surgery, Lausanne (Switzerland)

2014-12-15

The Contegra registered is a conduit made from the bovine jugular vein and then interposed between the right ventricle and the pulmonary artery. It is used for cardiac malformations in the reconstruction of right ventricular outflow tract. To describe both normal and pathological appearances of the Contegra registered in radiological imaging, to describe imaging of complications and to define the role of CT and MRI in postoperative follow-up. Forty-three examinations of 24 patients (17 boys and 7 girls; mean age: 10.8 years old) with Contegra registered conduits were reviewed. Anatomical description and measurements of the conduits were performed. Pathological items examined included stenosis, dilatation, plicature or twist, thrombus or vegetations, calcifications and valvular regurgitation. Findings were correlated to the echographic gradient through the conduit when available. CT and MR work-up showed Contegra registered stenosis (n = 12), dilatation (n = 9) and plicature or twist (n = 7). CT displayed thrombus or vegetations in the Contegra registered in three clinically infected patients. Calcifications of the conduit were present at CT in 12 patients and valvular regurgitation in three patients. The comparison between CT and/or MR results showed a good correlation between the echographic gradient and the presence of stenosis in the Contegra registered. CT and MR bring additional information about permeability and postoperative anatomy especially when echocardiography is inconclusive. Both techniques depict the normal appearance of the conduit, and allow comparison and precise evaluation of changes in the postoperative follow-up. (orig.)

Cardiac MRI in addition to MR angiography: a longitudinal study in vascular risk patients; Kardiale MRT als Ergaenzung zur MR-Angiografie: Eine longitudinale Studie bei vaskulaeren Risikopatienten

Energy Technology Data Exchange (ETDEWEB)

Seeger, A.; Grimm, F.; Fenchel, M.; Kramer, U.; Doering, J.S.; Klumpp, B.; Claussen, C.D.; Miller, S. [Abt. fuer Radiologische Diagnostik, Eberhard-Karls-Univ. Tuebingen (Germany); Scheule, A. [Abt. fuer Herz-, Thorax- und Gefaesschirurgie, Eberhard-Karls-Univ. Tuebingen (Germany); May, A.E. [Abt. fuer Kardiologie, Eberhard-Karls-Univ. Tuebingen (Germany)

2008-05-15

Purpose: the aim of the study was to assess the feasibility and additional diagnostic information of cardiac MRI as a supplement to state-of-the-art MR angiography (MRA) in the case of vascular risk patients. Therefore, the prevalence of delayed myocardial enhancement (DE) was determined in patients suffering from peripheral artery disease (PAD) and a clinical follow-up was evaluated after 2 years. Materials and method: 87 consecutive patients (ages 66 {+-} 10 years, 67 males) with symptomatic peripheral arterial occlusive disease (n = 68) or abdominal aortic aneurysm (n = 19) were examined using delayed cardiac enhancement (DE) within the clinical indication of MRA at a 1.5T system. A follow-up examination was carried out two years later (24 months {+-} 4 months) with regards to cardiac events (cardiac death, myocardial infarction or acute coronary syndrome, heart insufficiency, coronary revascularization). Results: in total, 40/87 patients had myocardial infarctions shown in MRI (46%). In 25 patients (29%), the myocardial infarction was already known, while in 15 patients (17%) an occult progressing infarction was diagnosed (38% of the myocardial infarcts). Follow-up data was able to be obtained after 2 years for 82 patients. 15 patients had a major cardiac event during the follow-up period, and 10 (67%) of them already showed DE in the MRI. In the group with occult progressing infarctions, cardiac events occurred in 40% (6/15 patients, cardiac death n = 1, ischemia n = 4, heart insufficiency n = 1, bypass n = 1), in patients with known infarction in 17% (4/23 patients, cardiac death n = 1, ischemia n = 3, bypass n = 2) and in 11% of patients without myocardial scars (5/44 patients, cardiac death n = 1, ischemia n = 2, heart insufficiency n = 2). (orig.)

22 CFR 901.10 - Act.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Act. 901.10 Section 901.10 Foreign Relations FOREIGN SERVICE GRIEVANCE BOARD GENERAL Meanings of Terms As Used in This Chapter § 901.10 Act. Act means the Foreign Service Act of 1980 (Pub. L. 96-465, October 17, 1980), as amended. [56 FR 55458, Oct. 28...

17 CFR 401.5 - Exemption for corporate credit unions transacting limited government securities business with...

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption for corporate credit unions transacting limited government securities business with other credit unions. 401.5 Section 401.5... government securities business with other credit unions. (a)(1) Subject to the requirements of paragraph (b...

Protecting Government Works: The Copyright Issue

National Research Council Canada - National Science Library

Manz, Paul C; Zelenka, Michael J; Wittig, Raymond S; Smith, Sally A

2002-01-01

The federal government, through its employees and contractors, produces commercially valuable inventions and information every day, often without any protection of the intellectual property involved...

Inventors and Inventions.

Science.gov (United States)

Dawson, Tom

An 8-day unit introduces middle school students to American inventors and inventions. In separate lessons, students examine the patenting process, women inventors, minority inventors, Native American inventors, the airplane, Thomas Edison, and the impact of inventions on America's growth. A brief outline of daily lesson plans precedes a section of…

Simultaneous invention and the patent law

DEFF Research Database (Denmark)

Howells, John

inventions they often find this to challenge the idea that patent law (which rewards only the first inventor with exclusive rights) is needed to encourage invention and innovation. We review the empirical evidence alleged to show that simultaneous invention is prevalent for important inventions. In general...... is typical of important pioneer inventions in both survey evidence and alleged illustrative cases of simultaneous invention. We show this in the cases of Edison, the Wright brothers, the Selden automobile patent vis a vis Ford, Watt and the steam engine. We then point out that patent law inherently ensures...... that patent protection is not extended to near simultaneous inventions. There remain a number of simultaneous inventions discovered through interference proceedings but we find the number too small to mount a serious challenge to the general operation of patent law....

Health systems performance in sub-Saharan Africa: governance, outcome and equity.

Science.gov (United States)

Olafsdottir, Anna E; Reidpath, Daniel D; Pokhrel, Subhash; Allotey, Pascale

2011-04-16

The literature on health systems focuses largely on the performance of healthcare systems operationalised around indicators such as hospital beds, maternity care and immunisation coverage. A broader definition of health systems however, needs to include the wider determinants of health including, possibly, governance and its relationship to health and health equity. The aim of this study was to examine the relationship between health systems outcomes and equity, and governance as a part of a process to extend the range of indicators used to assess health systems performance. Using cross sectional data from 46 countries in the African region of the World Health Organization, an ecological analysis was conducted to examine the relationship between governance and health systems performance. The data were analysed using multiple linear regression and a standard progressive modelling procedure. The under-five mortality rate (U5MR) was used as the health outcome measure and the ratio of U5MR in the wealthiest and poorest quintiles was used as the measure of health equity. Governance was measured using two contextually relevant indices developed by the Mo Ibrahim Foundation. Governance was strongly associated with U5MR and moderately associated with the U5MR quintile ratio. After controlling for possible confounding by healthcare, finance, education, and water and sanitation, governance remained significantly associated with U5MR. Governance was not, however, significantly associated with equity in U5MR outcomes. This study suggests that the quality of governance may be an important structural determinant of health systems performance, and could be an indicator to be monitored. The association suggests there might be a causal relationship. However, the cross-sectional design, the level of missing data, and the small sample size, forces tentative conclusions. Further research will be needed to assess the causal relationship, and its generalizability beyond U5MR as a health

Health systems performance in sub-Saharan Africa: governance, outcome and equity

Directory of Open Access Journals (Sweden)

Pokhrel Subhash

2011-04-01

Full Text Available Abstract Background The literature on health systems focuses largely on the performance of healthcare systems operationalised around indicators such as hospital beds, maternity care and immunisation coverage. A broader definition of health systems however, needs to include the wider determinants of health including, possibly, governance and its relationship to health and health equity. The aim of this study was to examine the relationship between health systems outcomes and equity, and governance as a part of a process to extend the range of indicators used to assess health systems performance. Methods Using cross sectional data from 46 countries in the African region of the World Health Organization, an ecological analysis was conducted to examine the relationship between governance and health systems performance. The data were analysed using multiple linear regression and a standard progressive modelling procedure. The under-five mortality rate (U5MR was used as the health outcome measure and the ratio of U5MR in the wealthiest and poorest quintiles was used as the measure of health equity. Governance was measured using two contextually relevant indices developed by the Mo Ibrahim Foundation. Results Governance was strongly associated with U5MR and moderately associated with the U5MR quintile ratio. After controlling for possible confounding by healthcare, finance, education, and water and sanitation, governance remained significantly associated with U5MR. Governance was not, however, significantly associated with equity in U5MR outcomes. Conclusion This study suggests that the quality of governance may be an important structural determinant of health systems performance, and could be an indicator to be monitored. The association suggests there might be a causal relationship. However, the cross-sectional design, the level of missing data, and the small sample size, forces tentative conclusions. Further research will be needed to assess the

MR imaging of pontine infarction within 2 weeks after ictus

Energy Technology Data Exchange (ETDEWEB)

Uchino, Akira; Hata, Hirofumi; Ohno, Masato (Kyushu Rosai Hospital, Fukuoka (Japan))

1991-08-01

Magnetic resonance (MR) images of 10 patients with pontine infarction were reviewed. A total of 17 examinations were performed on a 1.5 Tesla high-field scanner (GE) within two weeks after ictus. The infarcted area was detected by MR as early as 20 hours after stroke in one case. However, MR images obtained in two cases three and nine hours after onset were unremarkable. It is therefore suggested that follow-up study should be performed when initial MR images within 20 hours postictus are normal. T{sub 1}-weighted images at four, nine and twelve days after ictus were interpreted as normal. In two of these three examinations, the infarcted areas were clearly demonstrated as hyperintense lesions on T{sub 2}-weighted images. In the other examination, however, an area of mildly increased signal intensity was seen on T{sub 2}-weighted images. This case suggests that the fogging effect is also observed on MR imaging and that a small pontine infarction may be overlooked during the subacute stage. Basilar artery occlusion was detected as an absence-of-flow void in three of the ten patients. In conclusion, MR imaging proved to be a relatively useful diagnostic modality for evaluating acute and subacute pontine infarction. (author).

Outcome After Pneumonectomy in 17 Dogs and 10 Cats: A Veterinary Society of Surgical Oncology Case Series.

Science.gov (United States)

Wavreille, Vincent; Boston, S E; Souza, C; Ham, K; Chanoit, G; Rossetti, D; Takacs, J; Milner, R

2016-08-01

To report the signalment, presenting clinical signs, surgical complications, histologic diagnosis, postoperative complications, and outcome of dogs and cats undergoing pneumonectomy. Retrospective case series; multicenter study. Client-owned dogs (n=17) and cats (n=10). Signalment, clinical signs, side affected, surgical data, preoperative diagnostic tests (including complete blood count, serum biochemistry, cytologic diagnosis, chest radiographs, and computed tomography), histologic diagnosis, surgical complications, adjunctive therapy, and date and cause of death were collected from records of dogs and cats that underwent pneumonectomy. Survival estimates and complication were assessed. Seventeen animals had a left-sided pneumonectomy performed (12 dogs, 5 cats) and 10 animals had a right-sided pneumonectomy (5 dogs, 5 cats). Fourteen animals were diagnosed with neoplasia (52%). The overall incidence of complications for dogs and cats were 76 and 80%, respectively, with major complications in 41 and 50%, respectively. Respiratory complications (persistent pleural effusion, oxygen dependence, persistent increased respiratory rate, or coughing) were the most frequent complications. No animals died or were euthanatized intraoperative or within the first 24 hours postoperative. One dog (6%) and 2 cats (20%) died, or were euthanatized in the first 2 weeks postoperative. Based on this case series, right and left pneumonectomy can be performed with low perioperative mortality in dogs and cats, with some animals experiencing prolonged survival. © Copyright 2016 by The American College of Veterinary Surgeons.

Invention party of students 1

International Nuclear Information System (INIS)

Wang, Yeon Jung

2000-02-01

The contents of this book are story about making a mistake by friends, o dear! my mistake, shower and platform for crocks of sauces and condiments, good thing and bad thing when it appears, dream and invention of JuMok, failure is another discovery, a certain goal, idea in a life, addition and subtraction, a little hint is a great invention, question : why? This book gives advices and encouragement how to invent and what to invent to students.

Seasonal influenza A/H3N2 virus infection and IL-1Β, IL-10, IL-17, and IL-28 polymorphisms in Iranian population.

Science.gov (United States)

Rogo, Lawal Dahiru; Rezaei, Farhad; Marashi, Seyed Mahdi; Yekaninejad, Mir Saeed; Naseri, Maryam; Ghavami, Nastaran; Mokhtari-Azad, Talat

2016-12-01

Increased blood cytokines is the main immunopathological process that were attributed to severe clinical outcomes in cases of influenza A/H3N2 virus infection. The study was aimed to investigate the polymorphisms of IL-1β, IL-10, IL-17, and IL-28 genes to find the possibility of their association with the clinical outcome of influenza A/H3N2 virus infection among the infected patients in Iran. This is a Case-Control study in which influenza A/H3N2 virus positive confirmed with real-time PCR were the cases. DNA samples from groups were genotyped for polymorphisms in rs16944 (IL-1β), rs1800872 (IL-10), rs2275913 (IL-17), and rs8099917 (IL-28). Confidence interval (95%CI) and Odds ratio (OR) were calculated. IL-17 rs2275913 (GG and AG) were associated with risk of infection with that were statistically significant (P rs16944) (GG) was associated with reduced risk of infection (P < 0.01, OR = 0.46). Genotype GG and GT of IL-10 (rs1800872) were associated with increased risk of infection with influenza A/H3N2 virus (P < 0.05, OR = 2.04-2.58). In addition, IL-28 (rs8099917) genotypes GG (P < 0.05, OR = 0.49) and TG (P < 0.05, OR = 0.59) were associated with reduced risk of ILI symptom while genotype TT (P < 0.01, OR = 4.31) was associated with increased risk of ILI symptom. The results of this study demonstrated that polymorphisms of genes involved in the inflammatory and anti-inflammatory process affect the outcome of disease caused by influenza A/H3N2 virus. Thorough insight on host immune response at the time of influenza A virus infection is required to ensure adequate patient care in the case of feature outbreaks. J. Med. Virol. 88:2078-2084, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Oculomotor paralysis: 3D-CISS MR imaging with MPR in the evaluation of neuralgic manifestation and the adjacent structures

Energy Technology Data Exchange (ETDEWEB)

Sun Xiaoli; Liang Changhu [Shandong Medical Imaging Research Institute, Shandong University, Jing-wu Road No. 324, Jinan 250021 (China); Liu Cheng [Shandong Medical Imaging Research Institute, Shandong University, Jing-wu Road No. 324, Jinan 250021 (China)], E-mail: sdsxl2005@126.com; Liu Shuwei; Deng Kai; He Jingzhen [Shandong Medical Imaging Research Institute, Shandong University, Jing-wu Road No. 324, Jinan 250021 (China)

2010-02-15

Purpose: To evaluate the value of three-dimensional (3D) constructive interference in steady-state (CISS) magnetic resonance (MR) imaging with multi-planar reconstruction (MPR) in displaying the relationship between the oculomotor nerve and its adjacent structures for patients with oculomotor paralysis. Materials and methods: 17 consecutive patients with oculomotor paralysis were examined with 3D-CISS and conventional spin-echo (SE) sequences on a 1.5-Tesla MR system. Original transverse and MPR images were used for image interpretation. The features of the oculomotor nerve and its adjacent structures were identified. The diagnosis was surgically confirmed in all patients. Results: Through 3D-CISS with MPR images, obvious relationship of the oculomotor nerve and its adjacent structures was demonstrated on 17 patients. Of those oculomotor nerves, 15 were compressed by the arteries (n = 15), one by the craniopharyngioma (n = 1), and another one by the neurofibroma (n = 1). Conclusion: 3D-CISS MR imaging with MPR provides an excellent way to characterize the relationship between the nerve and its adjacent structures in the cisternal segment of the oculomotor nerve in the patients with oculomotor paralysis. Moreover, this method shows anatomical details for imaging diagnosis and surgical procedure.

Oculomotor paralysis: 3D-CISS MR imaging with MPR in the evaluation of neuralgic manifestation and the adjacent structures

International Nuclear Information System (INIS)

Sun Xiaoli; Liang Changhu; Liu Cheng; Liu Shuwei; Deng Kai; He Jingzhen

2010-01-01

Purpose: To evaluate the value of three-dimensional (3D) constructive interference in steady-state (CISS) magnetic resonance (MR) imaging with multi-planar reconstruction (MPR) in displaying the relationship between the oculomotor nerve and its adjacent structures for patients with oculomotor paralysis. Materials and methods: 17 consecutive patients with oculomotor paralysis were examined with 3D-CISS and conventional spin-echo (SE) sequences on a 1.5-Tesla MR system. Original transverse and MPR images were used for image interpretation. The features of the oculomotor nerve and its adjacent structures were identified. The diagnosis was surgically confirmed in all patients. Results: Through 3D-CISS with MPR images, obvious relationship of the oculomotor nerve and its adjacent structures was demonstrated on 17 patients. Of those oculomotor nerves, 15 were compressed by the arteries (n = 15), one by the craniopharyngioma (n = 1), and another one by the neurofibroma (n = 1). Conclusion: 3D-CISS MR imaging with MPR provides an excellent way to characterize the relationship between the nerve and its adjacent structures in the cisternal segment of the oculomotor nerve in the patients with oculomotor paralysis. Moreover, this method shows anatomical details for imaging diagnosis and surgical procedure.

The Invention Convention: Mind Meets Simple Machines.

Science.gov (United States)

Hadi-Tabassum, Samina

1997-01-01

Describes an Earth Day celebration where students had to design an invention made of simple machines that could crush an empty aluminum can through 10 rapid mechanical movements using materials foraged from the students' homes. (JRH)

MR of experimental cerebral ischemia

International Nuclear Information System (INIS)

DeLaPaz, R.; Steinberg, G.; Rocklage, S.; Glover, G.H.

1990-01-01

This paper reports on MR imaging of cerebral ischemia and treatment with N-methyl-D-aspartate (NMDA) antagonists in an animal model. Forty-four New Zealand white rabbits underwent 1-hour transorbital ICA-MCA-ACA occlusion and pretreatment or immediate posttreatment with systemic dextromethorphan (DM, n = 14), dextrorphan (DX, n = 14), or normal saline (NS, n = 16). Serial MR studies (1.5 T) were performed 1--6 hours after occlusion with T1- and T2-weighted spinecho, IVIM (b = 1,352), gradient recalled acquisition in a steady-state, and chemical shift sequences (for magnetic susceptibility, T2* and T2') and DyDTPA-BMA intravenous contrast material (Salutar). Spatial correlation between MR findings, histologic findings (ischemic neuronal damage), and regional cerebral blood flow (microspheres) was done

Design and Construction Rules for Mechanical components of FBR nuclear islands: RCC-MR. Tome 1, Volume A: generalities

International Nuclear Information System (INIS)

1985-06-01

The French Rules of Mechanical equipments of Fast Neutron nuclear Reactors (RCC-MR) aims at equipments included in a safety classification. The equipments concerned are those of the nuclear boiler and its auxiliaries: tanks, vessels, internal equipments of the reactor, exchangers, pumps, fittings, pipes, and supports. The present edition of the RCC-MR comprises 12 books presented in the present one in the volume A. The chapter RA 3000 defines the documents to be established in application of the RCC-MR rules. The chapter RA 5000 defines the requirements to take into account to establish and carry out quality Assurance programs according to the RCC-MR rules [fr

Appearance of abdominal wall endometriosis on MR imaging

Energy Technology Data Exchange (ETDEWEB)

Busard, Milou P.H.; Kuijk, Cees van; Waesberghe, Jan Hein T.M. van [VU Medical Center, Department of Radiology, Endometriosis Center VUMC, Amsterdam (Netherlands); Mijatovic, Velja; Hompes, Peter G.A. [VU Medical Center, Department of Gynecology, Endometriosis Center, Amsterdam (Netherlands)

2010-05-15

Abdominal wall endometriosis (AWE) is defined as endometrial tissue that is superficial to the peritoneum. AWE is often difficult to diagnose, mimicking a broad spectrum of diseases. The aim of this study was to describe the appearance of AWE on magnetic resonance (MR) imaging. We present ten patients with AWE (12 lesions) in which MR imaging was used for diagnosis. MR imaging included T2-weighted imaging and T1-weighted imaging with fat suppression. To assess the value of diffusion-weighted imaging (DWI) in endometriosis, four patients underwent additional DWI. The apparent diffusion coefficient (ADC) was calculated using b values of 50, 400, 800 and 1,200 s/mm{sup 2}. In most cases, the lesion was located ventral or dorsal to the aponeurosis of the rectus oblique muscle (n=6) or in the rectus abdominis (n = 5). MR of AWE lesions showed isointense or slightly hyperintense signal compared with muscle on T2-weighted images and showed isointense or slightly hyperintense signal compared with muscle on T1-weighted images with foci of high signal intensity, indicative of haemorrhage. The mean ADC value of AWE was 0.93 x 10{sup -3}/mm{sup 2}/s. MR imaging seems to be useful in determining the location and depth of infiltration in surrounding tissue preoperatively. (orig.)

77 FR 46615 - Changes To Implement Miscellaneous Post Patent Provisions of the Leahy-Smith America Invents Act

Science.gov (United States)

2012-08-06

... the Leahy-Smith America Invents Act AGENCY: United States Patent and Trademark Office, Commerce. ACTION: Final rule. SUMMARY: The Leahy-Smith America Invents Act (AIA) expands the scope of information... instituted. Section 6(a) and (d) of the Leahy-Smith American Invents Act also contains provisions (35 U.S.C...

Economy and Transparency: The Model Invention

Directory of Open Access Journals (Sweden)

Mahmud Hassan TALUKDAR

2013-12-01

Full Text Available Relation of Transparency and Economic growth is a long global debate in the society. Theoretically, policy makers, scholars and researchers argue that there is a close relation among these two variables. However, the quantitative relation and any global model is yet unrevealed. So, the main aim of this paper is to ascertain the nature, dimension and extent of the relationship between economy and Transparency as well as to invent a global model. This paper is useful for researchers, planners, policy makers and scholars who are directly or indirectly involved or willing to involve in the thrust for quantitative relation of these two variables. Literature review is the main source of information of this study. In introductory section, this paper briefly describes theoretical relationship of economy and Transparency as well as it also describes the proxy variables.GDP (2012 of different countries are used as proxy of Economy and Corruption Perception Index (CPI scores (2012 of different countries are used as proxy of level of Transparency. In methodology section this paper describes the detail methodology, sampling procedure and level of analysis. This study randomly selects 30 countries (10 from higher CPI scores+10 from moderate CPI scores+ 10 from lower CPI scores around the globe as sample. In the third section, this research presents the correlation value which divulge that there is a positive correlation (p=.047 with 95% confidence level. That reveals, if the level of transparency of any country increase, the GDP also increase accordingly. Then in this section two quantitative models are developed using linear regression analysis. First invented model is: Economy (GDP in billion US$ = [(8.983*Level of transparency -108.11]. This paper termed the first invented model as “Mahmud EcoT Model-1”. This model calibrates that one unit improvement of transparency leads 8.98 billion US$ improvement in the GDP of a country. Then taking this unit

17 CFR 170.10 - Proficiency examinations (sections 4p and 17(p) of the Act).

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Proficiency examinations (sections 4p and 17(p) of the Act). 170.10 Section 170.10 Commodity and Securities Exchanges COMMODITY... examinations (sections 4p and 17(p) of the Act). A futures association may prescribe different training...

Invention through Form and Function Analogy

Science.gov (United States)

Rule, Audrey C.

2015-01-01

"Invention through Form and Function Analogy" is an invention book for teachers and other leaders working with youth who are involving students in the invention process. The book consists of an introduction and set of nine learning cycle formatted lessons for teaching the principles of invention through the science and engineering design…

Quantitative comparison of PET performance—Siemens Biograph mCT and mMR

Energy Technology Data Exchange (ETDEWEB)

Karlberg, Anna M.; Sæther, Oddbjørn [Department of Radiology and Nuclear Medicine, St. Olavs Hospital, Olav Kyrres gt 17, 7006 Trondheim (Norway); Eikenes, Live [Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Postbox 8905, 7491 Trondheim (Norway); Goa, Pål Erik [Department of Radiology and Nuclear Medicine, St. Olavs Hospital, Olav Kyrres gt 17, 7006 Trondheim (Norway); Department of Physics, Norwegian University of Science and Technology, Trondheim (Norway)

2016-02-25

Integrated clinical whole-body PET/MR systems were introduced in 2010. In order to bring this technology into clinical usage, it is of great importance to compare the performance with the well-established PET/CT. The aim of this study was to evaluate PET performance, with focus on image quality, on Siemens Biograph mMR (PET/MR) and Siemens Biograph mCT (PET/CT). A direct quantitative comparison of the performance characteristics between the mMR and mCT system was performed according to National Electrical Manufacturers Association (NEMA) NU 2-2007 protocol. Spatial resolution, sensitivity, count rate and image quality were evaluated. The evaluation was supplemented with additional standardized uptake value (SUV) measurements. The spatial resolution was similar for the two systems. Average sensitivity was higher for the mMR (13.3 kcps/MBq) compared to the mCT system (10.0 kcps/MBq). Peak noise equivalent count rate (NECR) was slightly higher for the mMR (196 kcps @ 24.4 kBq/mL) compared to the mCT (186 kcps @ 30.1 kBq/mL). Scatter fractions in the clinical activity concentration range yielded lower values for the mCT (34.9 %) compared to those for the mMR (37.0 %). Best image quality of the systems resulted in approximately the same mean hot sphere contrast and a difference of 19 percentage points (pp) in mean cold contrast, in favour of the mCT. In general, point spread function (PSF) increased hot contrast and time of flight (TOF) increased both hot and cold contrast. Highest hot contrast for the smallest sphere (10 mm) was achieved with the combination of TOF and PSF on the mCT. Lung residual error was higher for the mMR (22 %) than that for the mCT (17 %), with no effect of PSF. With TOF, lung residual error was reduced to 8 % (mCT). SUV was accurate for both systems, but PSF caused overestimations for the 13-, 17- and 22-mm spheres. Both systems proved good performance characteristics, and the PET image quality of the mMR was close to that of the m

17 CFR 270.30b1-2 - Semi-annual report for totally-owned registered management investment company subsidiary of...

Science.gov (United States)

2010-04-01

...-owned registered management investment company subsidiary of registered management investment company...-owned registered management investment company subsidiary of registered management investment company... subsidiary of a registered management investment company need not file a semi-annual report on Form N-SAR if...

76 FR 59115 - Notice of Availability of Patent Fee Changes Under the Leahy-Smith America Invents Act

Science.gov (United States)

2011-09-23

... Availability of Patent Fee Changes Under the Leahy- Smith America Invents Act AGENCY: United States Patent and... of the Leahy-Smith America Invents Act (i.e., September 26, 2011) by operation of the fifteen percent... in effect sixty days after the date of enactment of the Leahy-Smith America Invents Act (i.e...

Overcome IMF crisis with idea and invention

International Nuclear Information System (INIS)

Wang, Yeon Jung

1998-01-01

This book introduces the invention as a tool to overcome IMF crisis. These are the titles of the way to create invention and idea : what is idea? everyone can create something, have a confidence, this is patent, replace or change something, invention is not logical, challenge the normal law, throw away stereotype, movement of idea, original imagination, there are a lot of solutions, there is no expert, have a positive thought, why does inventor invent? necessity is invention of mother, three stage of idea and invention and imitation for invention.

Overcome IMF crisis with idea and invention

Energy Technology Data Exchange (ETDEWEB)

Wang, Yeon Jung

1998-01-15

This book introduces the invention as a tool to overcome IMF crisis. These are the titles of the way to create invention and idea : what is idea? everyone can create something, have a confidence, this is patent, replace or change something, invention is not logical, challenge the normal law, throw away stereotype, movement of idea, original imagination, there are a lot of solutions, there is no expert, have a positive thought, why does inventor invent? necessity is invention of mother, three stage of idea and invention and imitation for invention.

17 CFR 401.7 - Temporary exemption for certain government securities brokers and dealers terminating business on...

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Temporary exemption for certain government securities brokers and dealers terminating business on or before October 31, 1987. 401... government securities brokers and dealers terminating business on or before October 31, 1987. During the...

77 FR 65545 - Mr. Jesse S. Capel and Mr. Hilton J. Cochran; EWP LLC; Notice of Transfer of Exemption

Science.gov (United States)

2012-10-29

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 4815-009] Mr. Jesse S. Capel and Mr. Hilton J. Cochran; EWP LLC; Notice of Transfer of Exemption 1. By application filed on July 30, 2012 and supplemented on August 14, 2012, Mr. Jesse S. Capel and Mr. Hilton J. Cochran and EWP...

MR myelography of sacral meningeal cysts

International Nuclear Information System (INIS)

Tsuchiya, K.; Katase, S.; Hachiya, J.

1999-01-01

Purpose: To describe the findings of sacral meningeal cysts (SMCs) on MR myelography and assess its value for the diagnosis of SMCs. Material and Methods: We evaluated the MR images and MR myelograms obtained from 10 patients with SMC. MR myelograms were obtained using a 2D or 3D single-shot fast spin-echo sequence. In 5 patients, X-ray myelograms and postmyelographic CT images were compared with the MR myelograms. Results: A total of 33 SMCs were diagnosed within the spinal canal and/or sacral foramen. MR myelograms clearly revealed each cyst as a well-defined mass showing hyperintensity (10 cysts) or isointensity (23 cysts) compared to cerebrospinal fluid. MR myelograms demonstrated SMCs better than X-ray myelograms and postmyelographic CT images in 3 of the 5 patients. Conclusion: MR myelography can be an adjunct to conventional imaging techniques when surgical treatment is indicated, because it can precisely delineate the extent of SMCs. (orig.)

MR findings in patients with disabling musculocutaneous chronic graft-versus-host disease

Energy Technology Data Exchange (ETDEWEB)

Horger, M.; Boss, A.; Claussen, C.D. [Eberhard-Karls-University, Department of Diagnostic Radiology, Tuebingen (Germany); Bethge, W.; Faul, C.; Vogel, W. [Eberhard-Karls-University, Department of Internal Medicine-Oncology, Tuebingen (Germany); Fierlbeck, G. [Eberhard-Karls-University, Department of Dermatology, Tuebingen (Germany); Bornemann, A. [Eberhard-Karls-University, Insitute for Brain Research, Tuebingen (Germany)

2008-10-15

To describe musculocutaneous MR-findings responsible for disability in chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic cell transplantation (HCT). Between June 2005 and February 2008, we performed whole-body musculoskeletal magnetic resonance imaging (MRI; n = 12) or regional MRI (n = 4) in 16 consecutive patients presenting with disabling sclerodermatous cGVHD (e.g., skin edema, fixed deep dermal sclerosis, joint contractures, painful muscular contractures, or myalgia). In all patients, MRI showed musculocutaneous abnormalities reflecting different degrees of inflammation and collagen tissue involvement of the skin (n = 10), subcutaneous fat tissue (n = 13), muscle fasciae (n = 16), subfascial muscular septae (n = 6), or findings compatible with myositis (n = 3). The most frequently involved muscle fasciae comprised those of the vastus lateralis muscle (n = 12), biceps femoris muscle (n = 11), gastrocnemius medialis muscle (n = 8), serratus anterior muscle, and latissimus dorsi muscle (each, n = 5). Increased signal of involved tissues on STIR-images and fat-saturated postgadolinium T1-weighted images represented the most frequent MR-signal abnormalities. MR imaging of musculocutaneous cGVHD allows accurate evaluation including assessment of deep tissue infiltration and assists in the differential diagnosis. (orig.)

MR findings in patients with disabling musculocutaneous chronic graft-versus-host disease

International Nuclear Information System (INIS)

Horger, M.; Boss, A.; Claussen, C.D.; Bethge, W.; Faul, C.; Vogel, W.; Fierlbeck, G.; Bornemann, A.

2008-01-01

To describe musculocutaneous MR-findings responsible for disability in chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic cell transplantation (HCT). Between June 2005 and February 2008, we performed whole-body musculoskeletal magnetic resonance imaging (MRI; n = 12) or regional MRI (n = 4) in 16 consecutive patients presenting with disabling sclerodermatous cGVHD (e.g., skin edema, fixed deep dermal sclerosis, joint contractures, painful muscular contractures, or myalgia). In all patients, MRI showed musculocutaneous abnormalities reflecting different degrees of inflammation and collagen tissue involvement of the skin (n = 10), subcutaneous fat tissue (n 13), muscle fasciae (n = 16), subfascial muscular septae (n = 6), or findings compatible with myositis (n = 3). The most frequently involved muscle fasciae comprised those of the vastus lateralis muscle (n = 12), biceps femoris muscle (n = 11), gastrocnemius medialis muscle (n = 8), serratus anterior muscle, and latissimus dorsi muscle (each, n = 5). Increased signal of involved tissues on STIR-images and fat-saturated postgadolinium T1-weighted images represented the most frequent MR-signal abnormalities. MR imaging of musculocutaneous cGVHD allows accurate evaluation including assessment of deep tissue infiltration and assists in the differential diagnosis. (orig.)

17 CFR 210.2-03 - Examination of financial statements by foreign government auditors.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Examination of financial statements by foreign government auditors. 210.2-03 Section 210.2-03 Commodity and Securities Exchanges... auditors. Notwithstanding any requirements as to examination by independent accountants, the financial...

Bibliometric analysis of the Spanish MR radiological production (2001-2007)

International Nuclear Information System (INIS)

Miguel-Dasit, Alberto; Marti-Bonmati, Luis; Sanfeliu, Pilar

2008-01-01

Objective: To evaluate the number and characteristics of papers on MR imaging written by radiologists in Spain and published in 2001-2007 Medline-indexed journals, including a comparison with the MR research output from German radiological departments. Materials and methods: Specific search profiles were devised to retrieve items from the Medline database. Relationship with the topic and major thematic areas of the articles, publication year, journal, language of publication, and mean impact factors were analyzed. Spanish and the German institutions with the highest MR productivity were identified. Also, the number of articles from Spain and Germany published in their respective official journals (Radiologia and ROFO) was recorded. Results: There were 332 Spanish articles published in 101 different journals. The higher number of papers was published in Spanish radiology and non-radiology journals (n = 105, 32%, mean IF: 0.191). The journal with the higher number of articles was Radiologia (n = 51, 15%). 'Neuroradiology' was the most frequent topic (n = 139, 42%). The Spanish productivity on MR imaging was yearly stable (p = 0.67), with the higher percentage of papers (17%) published in 2006. The topic with the higher IF was 'neuroradiology' (IF: 2.317). There were no yearly variations for the three major thematic areas ('Neuro imaging': p = 0.64; 'Body imaging': p = 0.91; and 'Non-clinical miscellanea': p = 0.46). The highest number of MR publications was found in two Spanish institutions (Dr. Peset University Hospital and Vall d'Hebron Hospital) (both, n = 28, 8%). In comparison, there were 1681 articles on MR imaging from Germany, having the two most productive institutions more than 150 papers in this period (University Hospital Essen and Eberhard-Karls University of Tuebingen). The adjusted number of articles per million populations was 20.4 for Germany and 8.1 for Spain. A total of 395 (23%) articles originating from Germany were published in the official

Tolerance of magnetic resonance imaging in children and adolescents performed in a 1.5 Tesla MR scanner with an open design

International Nuclear Information System (INIS)

Adamietz, B.; Cavallaro, A.; Radkow, T.; Alibek, S.; Bautz, W.A.; Holter, W.; Staatz, G.

2007-01-01

Purpose: To investigate the tolerance of MR examinations in children and adolescents performed in a 1.5 Tesla MR scanner with an expanded bore diameter. Method and Materials: 163 patients, ages 4 to 25, underwent MR examinations in a 1.5 Tesla MR scanner with an open design (MAGNETOM Espree, Siemens, Erlangen, Germany), characterized by a compact length of 125 cm and an expanded 70 cm bore diameter. MR imaging of the brain was carried out in most cases (78.5 %), followed by examinations of the spinal canal (9.8 %), the extremities (9.2 %) and the neck (2.5 %). The patients were divided into four age groups and the success rate, motion artifacts and diagnostic quality of the MR examinations were assessed using a 3-grade scale. Results: In 119 of 163 patients (73.0 %), MR examination was possible without any motion artifacts. With respect to the different age groups, 41.7 % of the 4 - 7-year-old children, 67.6 % of the 8 - 10-year-old children, 84.1 % of the 11 - 16-year-old children and 95.8 % of the patients older than 17 showed tolerance grade I without motion artifacts and excellent diagnostic image quality. In 39 of 163 children (23.9 %), the MR images showed moderate motion artifacts but had sufficient diagnostic quality. With regard to the different age groups, 52.8 % of the 4 - 7-year-old children, 26.5 % of the 8 - 10-year-old children, 15.9 % of the 11 - 16-year-old children and none of the patients older than 17 showed tolerance grade II with moderate motion artifacts and sufficient diagnostic image quality. In only 4 of 124 children 10 years old, the MR examination was not feasible and had to be repeated under sedation. Conclusion: Pediatric MR imaging using a 1.5 Tesla MR scanner with an open design can be conducted in children and adolescents with excellent acceptance. The failure rate of 3.0 % of cases for pediatric MR imaging is comparable to that of a conventional low-field open MR scanner. (orig.)

75 FR 11899 - Certificate of Alternative Compliance for the Tugboat MR JOE

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2010-03-12

... clicking ''Search.'' FOR FURTHER INFORMATION CONTACT: If you have questions on this notice, call CWO2 David Mauldin, District Eight, Prevention Branch, U.S. Coast Guard, telephone 504-671-2153. If you have... issued for the tugboat MR JOE, O.N. 1218724. Full compliance with 72 COLREGS and Inland Rules Act would...

78 FR 31989 - Government In the Sunshine Meeting Notice

Science.gov (United States)

2013-05-28

... Be Considered (Closed to the Public 10:15 a.m.) 1. Finance Project--Chile 2. Finance Project--Chile 3. Finance Project--Malaysia 4. Finance Project--Uruguay 5. Minutes of the Closed Session of the March 21..., 2013. Connie M. Downs, Corporate Secretary, Overseas Private Investment Corporation. [FR Doc. 2013...

Communication of 10 January 2008 received from the Permanent Mission of the United Kingdom regarding the Export of Nuclear Material and of Certain Categories of Equipment and Other Material

International Nuclear Information System (INIS)

2008-01-01

The Director General has received a note ver bale from the Permanent Mission of the United Kingdom, dated 10 January 2008, in which it requests that the Agency circulate to all Member States a letter of 12 December 2006 from the Chairman of the Zangger Committee, Mr. Pavel Klucky, to the Director General, on behalf of the Governments of Argentina, Australia, Austria, Belgium, Bulgaria, Canada, China, Croatia, Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Republic of Korea, Luxemburg, the Netherlands, Norway, Poland, Portugal, Romania, Russian Federation, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America, concerning the export of nuclear material and of certain categories of equipment and other material [fr

Scientific work on the level of inventions

Energy Technology Data Exchange (ETDEWEB)

Piven' , G.I.; Pustovit, Yu.A.

1980-06-01

Describes the organizational scheme of the Ukrainian Research Scientific Coal-Chemical Institute patent department. The department evaluates new technological inventions patented abroad and associated with the coking industry, prepares information on new patents for the Institute's scientific staff. The department also helps employees of the Institute in formal patenting of their inventions. Inventions in the following fields are discussed: selective crushing of coal for coking, preheating of the coal charge, coal preparation (15 inventions) coal preparation before the coking process (45 inventions), modelling the optimum parameters of coking (6 inventions), production of formed coke (25 inventions) and smokeless and dustless charging of coal in coking ovens (6 invections). Twenty-one inventions are associated with using the waste products of coal preparation and coking, and environmental protection in conjunction with coking plants. (In Polish)

17 CFR 210.3-09 - Separate financial statements of subsidiaries not consolidated and 50 percent or less owned persons.

Science.gov (United States)

2010-04-01

... financial statements of subsidiaries not consolidated and 50 percent or less owned persons. (a) If any of... consolidated financial statements required by §§ 210.3-01 and 3-02. However, these separate financial... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Separate financial statements...

MR findings in acute disseminated encephalomyelitis in children

International Nuclear Information System (INIS)

Kim, Wha Young; Kim, In One; Kim, Woo Sun; Yeon, Kyung Mo

2006-01-01

We reviewed the distribution of lesion and the characteristics of the MR findings of acute disseminated encephalomyelitis (ADEM) in children. We evaluated the differences in the imaging findings and the clinical outcomes between the patients with deep gray matter involvement and the patients without deep gray matter involvement. We retrospectively reviewed the 62 MR examinations of 21 patients who were discharged with the clinical diagnosis of ADEM. The patients were aged from 13 months to 12 years old (mean age: 4.5 years). Follow-up MR examinations were done one to 5 times (mean: 3 times) for 2 weeks to 4 years (mean: 3 months) after the initial examination. We compared the signal intensity on T2WI, the enhancement and residue on the MR images and the clinical outcomes between the patients with deep gray matter involvement and the patients without deep gray matter involvement. A total of 21 patients had white matter abnormalities on their initial MR. Fifteen patients (71%) had foci of increased signal intensity on T2WI in the deep gray matter: thalamus (n=15), globus pallidus (n=14) and putamen (n=10). On the follow-up images, all patients showed decreased signal intensity and enhancement of their lesion. We could not find the significant differences in signal intensity, enhancement and residue on the MRIs and also the clinical outcomes between the patients with deep gray matter involvement and the patients without deep gray matter involvement (<.05). There were no significant differences in the characteristics of the imaging and the clinical outcomes between the ADEM patients with deep gray matter involvement and those ADEM patients without deep gray matter involvement

MR elastography: high rate of technical success in pediatric and young adult patients

Energy Technology Data Exchange (ETDEWEB)

Joshi, Madalsa [British Columbia Children' s Hospital, Department of Radiology, Vancouver, BC (Canada); Dillman, Jonathan R.; Towbin, Alexander J.; Serai, Suraj D.; Trout, Andrew T. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, MLC 5031, Cincinnati, OH (United States)

2017-06-15

Magnetic resonance (MR) elastography allows the noninvasive assessment of liver stiffness, which is a surrogate for fibrosis. The purpose of this study was to describe our experience using liver MR elastography in a large pediatric population with attention to the frequency and causes of exam failure. Imaging records were searched for patients ≤18 years of age who underwent 2-D gradient recalled echo (GRE) MR elastography of the liver between September 2011 and August 2015 on one of two 1.5-T MRI platforms. Imaging reports and clinical records were reviewed for failed MR elastography acquisitions, factor(s) resulting in failure and whether a subsequent successful examination had been performed. Four hundred sixty-eight MR elastography examinations were performed in 372 patients between 1.5 months and 18 years of age during the study period. Ninety-six percent (450/468) of the examinations were successful. There was no significant difference in mean age (12.6±3.6 vs. 11.2±4.1 years, P=0.12) or body mass index (BMI) (28.2±12.4 vs. 29.5±10 kg/m{sup 2}, P=0.6) between patients with and without successful examinations. MR elastography failures were due to poor paddle positioning resulting in inadequate generation of hepatic shear waves (n=5), iron overload (n=4), patient inability to tolerate MRI (n=3), patient breathing/motion (n=3), artifact from implanted hardware (n=1) and technical malfunction (n=2). Seven of nine (78%) repeat examinations were successful (78%). Hepatic 2-D GRE MR elastography at 1.5 T is technically robust in children. Exam failure is infrequent and largely reflects patient specific factors, some of which can be mitigated with careful technique. (orig.)

MR-guided discography using an open 1 Tesla MRI system

International Nuclear Information System (INIS)

Streitparth, Florian; Bucourt, M. de; Hamm, B.; Teichgraeber, U.; Hartwig, T.; Strube, P.; Putzier, M.; Schnackenburg, B.; Chopra, S.

2011-01-01

To evaluate the feasibility of MR-guided discography using an open 1 Tesla MRI system. 48 disc segments of 41 patients scheduled for intradiscal thermal treatment, total disc replacement or spondylodesis were examined. A 1.0-T open MRI was used for instrument guidance and imaging. After primary disc puncture under guidance of interactive PDw TSE imaging, 1-2 ml of gadolinium contrast saline mixture was injected into the disc. The occurrence of memory pain during injection was recorded. Axial and sagittal T1w TSE images with and without fat saturation were obtained. All MRI discograms were analysed by two readers, who were blinded to the clinical findings. Overall, the placement of the puncture needle in the targeted disc was accurate under real-time MR guidance. Injections were technically successful in all cases. No major complications occurred. The mean procedure time was 17 min (range 13-34 min). Image quality of contrast-enhanced MR discograms was excellent when using an optimized gadolinium contrast saline mixture of 1:600. Memory pain was detected in 16 out of 48 affected segments. MR-guided discography is accurate and safe. Multiplanar dynamic imaging facilitates the puncture of discs and provides high-quality MR discograms. (orig.)

MR angiography of the TMJ in asymptomatic volunteers

International Nuclear Information System (INIS)

Takagi, Ritsuo; Ohashi, Yasushi; Westesson, P.L.; Togashi, Hirosuke

1998-01-01

To evaluate the vascular anatomy of the temporomandibular joint (TMJ) and surrounding soft tissue non-invasively, we applied magnetic resonance (MR) angiography for delineating the arterial architecture around the TMJ. MR angiograms of the left and right TMJs in asymptomatic volunteers were obtained using 3D/Time-of-flight (TOF) (First Field Echo, TR/TE/FLIP=46 ms/6.8 ms/17 deg) with intravenous contrast. These MR angiograms were compared with experimental angiograms of human TMJ autopsy specimens in order to identify each of the branches of the arteries on the MR angiograms. This study enabled the depiction by MR angiography of arterial vessels around the TMJ region to some degree. In conclusion, MR angiography appears promising as a non-invasive tool to evaluate the vascular anatomy of the TMJ. (author)

Discrete-time sliding mode control for MR vehicle suspension system

Energy Technology Data Exchange (ETDEWEB)

Sohn, J W; Choi, S B [Smart Structures and Systems Laboratory, Department of Mechanical Engineering, Inha University, Incheon 402-751 (Korea, Republic of); Wereley, N M [Smart Structures Laboratory, Department of Aerospace Engineering, University of Maryland, College Park, MD 20742 (United States)], E-mail: seungbok@inha.ac.kr

2009-02-01

This paper presents control performance of a full-vehicle suspension system featuring magnetorheological (MR) dampers via a discrete-time sliding mode control algorithm (DSMC). A cylindrical MR damper is designed by incorporating Bingham model of the MR fluid and the field-dependent damping characteristics of the MR damper are evaluated. A full-vehicle suspension model installed with independent four MR dampers is constructed and the governing equations which include vertical, pitch and roll motion are derived. A discrete-time control model is established with considering system uncertainties and a discrete-time sliding mode controller which has inherent robustness to model uncertainty and external disturbance is formulated. Vibration control performances under bump excitation are evaluated and presented.

Discrete-time sliding mode control for MR vehicle suspension system

International Nuclear Information System (INIS)

Sohn, J W; Choi, S B; Wereley, N M

2009-01-01

This paper presents control performance of a full-vehicle suspension system featuring magnetorheological (MR) dampers via a discrete-time sliding mode control algorithm (DSMC). A cylindrical MR damper is designed by incorporating Bingham model of the MR fluid and the field-dependent damping characteristics of the MR damper are evaluated. A full-vehicle suspension model installed with independent four MR dampers is constructed and the governing equations which include vertical, pitch and roll motion are derived. A discrete-time control model is established with considering system uncertainties and a discrete-time sliding mode controller which has inherent robustness to model uncertainty and external disturbance is formulated. Vibration control performances under bump excitation are evaluated and presented.

50 CFR Table 5 (south) to Part 660... - 2009-2010 Trip Limits for Open Access Gears South of 40°10′ N. Lat.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false 2009-2010 Trip Limits for Open Access Gears South of 40°10â² N. Lat. 5 Table 5 (South) to Part 660, Subpart G Wildlife and Fisheries FISHERY... Trip Limits for Open Access Gears South of 40°10′ N. Lat. Link to an amendment published at 75 FR 60995...

50 CFR Table 5 (north) to Part 660... - 2009-2010 Trip Limits for Open Access Gears North of 40°10′ N. Lat.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false 2009-2010 Trip Limits for Open Access Gears North of 40°10â² N. Lat. 5 Table 5 (North) to Part 660, Subpart G Wildlife and Fisheries FISHERY... Trip Limits for Open Access Gears North of 40°10′ N. Lat. Link to an amendment published at 75 FR 60995...

Ergonomics productivity enhancement at government-owned sugar cane factories in east Java, Indonesia.

Science.gov (United States)

Manuaba, A

1995-06-01

To cope, both with the increasing demand for sugar and to win the global competition as well, government-owned sugar cane limited number xxi-xxii, has decided to enhance its productivity, among other things, by implementing ergonomics principles within their factories. In the execution, ergonomics application have been carried out since 1992, which resulted in safer, healthier, and more efficient working conditions and environment. Some of the improvements yielded economic gains through higher productivity via increased output, lower cost, faster processing, etc. Improvements related to cane transloading and unloading processes resulted in a higher amount of cane being transferred from the trucks to the lorries as well as from the lorries to the cane table. Fewer clinical visits, lower health care costs, more efficient inspection, and fewer fatigue complaints are also achieved by improvement steps, which increase the productivity as end results. With all those economic gains, full and long lasting management's concern and commitment could be created without a doubt.

Why Is Hard To Patent An Invention?

Directory of Open Access Journals (Sweden)

2007-01-01

Full Text Available When employed by a company, in almost all the cases a new employee has to sign an agreement giving the company exclusive rights to any intellectual property developed as part of their work assignments. This agreement could extend beyond a change of jobs and cause conflict of interests in new employment situations. A patent is a government-granted monopoly given to an inventor as both a reward for the intellectual and financial investment, and a stimulus to innovate. As a monopoly, the patent has legal power to exclude others from exploiting the invention in any way for a period of 20 years from the time the patent application has been filed. A trademark provides instant recognition of a product or company; a service mark provides instant recognition of a service. They both have unlimited lifetime. But the owner must renew or confirm continuous use at the end of five years, and every 10 years thereafter. A trade secret is information keep secret by the owner to give him advantage over competitors. Since it is secret, a trade secret protection has unlimited lifetime.

MR-guided direct arthrography of the glenohumeral joint

International Nuclear Information System (INIS)

Soh, E.; Bearcroft, P.W.P.; Graves, M.J.; Black, R.; Lomas, D.J.

2008-01-01

Aim: To evaluate the feasibility of magnetic resonance (MR)-guided direct arthrography of the glenohumeral joint with a 1.5 T MR system, performing the entire procedure in a single MR examination. Materials and methods: MR-guided direct arthrography was performed on 11 patients. MR imaging guidance and interactive MR fluoroscopy, with in-room control and display system, were used for needle placement and contrast medium injection. The outcome measures were success or failure of joint puncture, the time taken for introduction of contrast medium, and the diagnostic quality of the subsequent MR arthrography images. Results: Contrast medium was successfully instilled into the joint and diagnostic quality MR arthrography images were obtained in all cases. The median time from initial placement of the skin marker to introduction of the contrast medium was 17 min (range 11-29 min). There were no immediate post-procedure complications. Conclusion: Accurate needle placement is feasible in a single MR examination on a commercial 1.5 T closed-bore MR system, using an in-room control and display system together with interactive fluoroscopic imaging, and this was used to provide direct MR arthrography in this study

Magnetoresistance and anomalous Hall effect of reactive sputtered polycrystalline Ti1 - XCrxN films

KAUST Repository

Duan, Xiaofei

2013-09-01

The reactive-sputtered polycrystalline Ti1 - xCrxN films with 0.17 ≤ x ≤ 0.51 are ferromagnetic and at x = 0.47 the Curie temperature TC shows a maximum of ~ 120 K. The films are metallic at 0 ≤ x ≤ 0.47, while the films with x = 0.51 and 0.78 are semiconducting-like. The upturn of resistivity below 70 K observed in the films with 0.10 ≤ x ≤ 0.47 is from the effects of the electron-electron interaction and weak localization. The negative magnetoresistance (MR) of the films with 0.10 ≤ x ≤ 0.51 is dominated by the double-exchange interaction, while at x = 0.78, MR is related to the localized magnetic moment scattering at the grain boundaries. The scaling ρxyA/n ∝ ρxx2.19 suggests that the anomalous Hall effect in the polycrystalline Ti1 - xCrxN films is scattering-independent. © 2013 Elsevier B.V. All rights reserved.

MR imaging of spinal trauma

International Nuclear Information System (INIS)

Buchberger, W.; Springer, P.; Birbamer, G.; Judmaier, W.; Kathrein, A.; Daniaux, H.

1995-01-01

To assess the value of MR imaging in the acute and chronic stages of spinal trauma. 126 MR examinations of 120 patients were evaluated retrospectively. In 15 cases of acute spinal cord injury, correlation of MR findings with the degree of neurological deficit and eventual recovery was undertaken. Cord anomalies in the acute stage were seen in 16 patients. Intramedullary haemorrhage (n=6) and cord transection (n=2) were associated with complete injuries and poor prognosis, whereas patients with cord oedema (n=7) had incomplete injuries and recovered significant neurological function. In the chronic stage, MR findings included persistent cord compression in 8 patients, syringomyelia or post-traumatic cyst in 12, myelomalacia in 6, cord atrophy in 9, and cord transection in 7 patients. In acute spinal trauma, MR proved useful in assessing spinal cord compression and instability. In addition, direct visualisation and characterisation of posttraumatic changes within the spinal cord may offer new possibilities in establishing the prognosis for neurological recovery. In the later stages, potentially remediable causes of persistent or progressive symptoms, such as chronic spinal cord compression or syringomyelia can be distinguished from other sequelae of spinal trauma, such as myelomalacia, cord transection or atrophy. (orig.) [de

Fast FLAIR MR images of intracranial hemorrhage

International Nuclear Information System (INIS)

Chun, Eun Ju; Choi, Hye Young; Cho, Young A; Kim, Wha Young

1998-01-01

The purpose of this study is to evaluate the signal characteristics of intracranial hemorrhage, as seen on fluid attenuated inversion recovery (FLAIR) MR imaging according to various stages, and to compare FLAIR imaging with spin-echo T1- and T2-weighted MR imaging. We retrospectively evaluated fast FLAIR images along with spin-echo T1- and T2 weighted MR images of 32 lesions in 25 patients (12 males and 14 females, aged 3 - 84 yrs) with intracranial hemorrhagic lesions. For imaging, 1.5 T unit was used, and the nature of the lesions was found to be as follows : intracranial hemorrhage (n=15); tumor (n=9); infarction (n=4); arteriovenous malformation (n=3); and arachnoid cyst with hemorrhage (n=1). On the basis of spin-echo MR imaging, lesions were classified as acute, early subacute, late subacute, early chronic, or late chronic stage. The signal characteristics of intracranial hemorrhage were analysed in accordance with each staging, as seen on MR FLAIR imaging, and compared to the staging seen on spin-echo T1- and T-2 weighted MR imaging. The signal intensity of intracranial hemorrhage, as seen on FLAIR imaging, was not characteristic; it was similar to that of T2WI during the acute and subacute stages, and similiar to that of T1WI during the chronic stage. When used together with spin-echo T1- and T2-weighted MR imaging, however, FLAIR imaging may be useful for the classification of chronic intracranial hemorrhage as either early or late stage. (author). 20 refs., 2 tabs., 6 figs

MR imaging of the juvenile temporomandibular joint before orthodontic treatment

International Nuclear Information System (INIS)

Lieberman, J.M.; Hans, M.G.; Rozencweig, G.; Goldberg, J.S.; Bellon, E.M.

1990-01-01

This paper determines the prevalence of internal derangement (ID) of the temporomandibular joint (TM) in a population of children prior to orthodontic therapy. Thirty-two children, aged 7-15 years, with a variety of orthodontic disorders underwent both MR imaging and physical examination to assess ID of the TMJ. With MR imaging, the disks were graded as normal, borderline anterior displaced, or anterior displaced. Fifty-nine TMJs in 32 patients were successfully imaged. Five TMJ MR examinations could not be interpreted because of patient motion. Fifty seven of the 59 joints (97%) were normal. One disk (1.7%) was anterior displaced, and one (1.7%) was considered borderline

The Invention Notebook Challenge

Science.gov (United States)

Roman, Harry T.

2018-01-01

Like scientists who keep lab notebooks detailing their experiments, inventors keep invention notebooks that chronologically detail the inception, development, and refinement of their inventions. These notebooks are legal documents that can help prove one inventor's precedent over another. Scenarios like these are very real, as the author has had…

Rómulo Betancourt, Juan D. Perón y el 17 de octubre de 1945

Directory of Open Access Journals (Sweden)

Ricardo Alberto Rivas

2005-11-01

Full Text Available Rómulo Betancourt y Juan D. Perón lideraron movimientos políticos considerados génesis de la democracia de masas en sus respectivos países, jalonada por sendos mítines populares del 17 de octubre de 1945 en Caracas y Buenos Aires, cuyo significado fue realzado como causa del proceso político ulterior. Pese a las diferencias, se destacan algunas semejanzas, tales como el contenido popular de ambos movimientos y cierta base de sustentación castrense. Se incluye un marco explicativo del proceso político venezolano precedente pero, en lo sustancial, el análisis se centra en el breve periodo transcurrido entre finales de la Segunda Guerra y el inicio de la Guerra Fría, cuando se produjeron cambios políticos en Argentina y Venezuela con un gran protagonismo de ambos dirigentes en sus respectivos países y en las recíprocas intromisiones que llevaron a cabo, enfatizando la oposición expresa de Betancourt hacia Perón desde el golpe de Estado del 4 de junio de 1943.

Intra-Arterial MR Perfusion Imaging of Meningiomas: Comparison to Digital Subtraction Angiography and Intravenous MR Perfusion Imaging.

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Mark A Lum

Full Text Available To evaluate the ability of IA MR perfusion to characterize meningioma blood supply.Studies were performed in a suite comprised of an x-ray angiography unit and 1.5T MR scanner that permitted intraprocedural patient movement between the imaging modalities. Patients underwent intra-arterial (IA and intravenous (IV T2* dynamic susceptibility MR perfusion immediately prior to meningioma embolization. Regional tumor arterial supply was characterized by digital subtraction angiography and classified as external carotid artery (ECA dural, internal carotid artery (ICA dural, or pial. MR perfusion data regions of interest (ROIs were analyzed in regions with different vascular supply to extract peak height, full-width at half-maximum (FWHM, relative cerebral blood flow (rCBF, relative cerebral blood volume (rCBV, and mean transit time (MTT. Linear mixed modeling was used to identify perfusion curve parameter differences for each ROI for IA and IV MR imaging techniques. IA vs. IV perfusion parameters were also directly compared for each ROI using linear mixed modeling.18 ROIs were analyzed in 12 patients. Arterial supply was identified as ECA dural (n = 11, ICA dural (n = 4, or pial (n = 3. FWHM, rCBV, and rCBF showed statistically significant differences between ROIs for IA MR perfusion. Peak Height and FWHM showed statistically significant differences between ROIs for IV MR perfusion. RCBV and MTT were significantly lower for IA perfusion in the Dural ECA compared to IV perfusion. Relative CBF in IA MR was found to be significantly higher in the Dural ICA region and MTT significantly lower compared to IV perfusion.

Aristotle's "Rhetoric": Reinterpreting Invention.

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Quandahl, Ellen

1986-01-01

Shows that Aristotle's common topics are part of a theory of interpretation rather than a collection of devices for invention. Argues that it is more Aristotelian and more useful to understand composing as interpretation and not invention. Uses scholarship to inform pedagogy and to reorient composing toward acts of reading. (EL)