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Sample records for flores population affinities

  1. The Flores Island tsunamis

    Science.gov (United States)

    Yeh, Harry; Imamura, Fumihiko; Synolakis, Costas; Tsuji, Yoshinobu; Liu, Philip; Shi, Shaozhong

    On December 12, 1992, at 5:30 A.M. GMT, an earthquake of magnitude Ms 7.5 struck the eastern region of Flores Island, Indonesia (Figure 1), a volcanic island located just at the transition between the Sunda and Banda Island arc systems. The local newspaper reported that 25-m high tsunamis struck the town of Maumere, causing substantial casualties and property damage. On December 16, television reports broadcast in Japan via satellite reported that 1000 people had been killed in Maumere and twothirds of the population of Babi Island had been swept away by the tsunamis.The current toll of the Flores earthquake is 2080 deaths and 2144 injuries, approximately 50% of which are attributed to the tsunamis. A tsunami survey plan was initiated within 3 days of the earthquake, and a cooperative international survey team was formed with four scientists from Indonesia, nine from Japan, three from the United States, one from the United Kingdom, and one from Korea.

  2. Genetic affinities between endogamous and inbreeding populations of Uttar Pradesh

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    Borkar Minal

    2007-04-01

    Full Text Available Abstract Background India has experienced several waves of migration since the Middle Paleolithic. It is believed that the initial demic movement into India was from Africa along the southern coastal route, approximately 60,000–85,000 years before present (ybp. It has also been reported that there were two other major colonization which included eastward diffusion of Neolithic farmers (Elamo Dravidians from Middle East sometime between 10,000 and 7,000 ybp and a southern dispersal of Indo Europeans from Central Asia 3,000 ybp. Mongol entry during the thirteenth century A.D. as well as some possible minor incursions from South China 50,000 to 60,000 ybp may have also contributed to cultural, linguistic and genetic diversity in India. Therefore, the genetic affinity and relationship of Indians with other world populations and also within India are often contested. In the present study, we have attempted to offer a fresh and immaculate interpretation on the genetic relationships of different North Indian populations with other Indian and world populations. Results We have first genotyped 20 tetra-nucleotide STR markers among 1800 north Indian samples of nine endogamous populations belonging to three different socio-cultural strata. Genetic distances (Nei's DA and Reynold's Fst were calculated among the nine studied populations, Caucasians and East Asians. This analysis was based upon the allelic profile of 20 STR markers to assess the genetic similarity and differences of the north Indian populations. North Indians showed a stronger genetic relationship with the Europeans (DA 0.0341 and Fst 0.0119 as compared to the Asians (DA 0.1694 and Fst – 0.0718. The upper caste Brahmins and Muslims were closest to Caucasians while middle caste populations were closer to Asians. Finally, three phylogenetic assessments based on two different NJ and ML phylogenetic methods and PC plot analysis were carried out using the same panel of 20 STR markers and 20

  3. PENENTUAN VEKTOR MALARIA DI FLORES

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    Harijani A. Marwoto

    2012-09-01

    Full Text Available A field study on entomology has been conducted in 6 villages which were located in coastal and in-land areas of Sikka Regency of Central Flores since April 1990 - October 1991. The results of this study showed that the suspected malaria vectors in those areas were An. sundaicus, An. subpictus, An. barbirostris, An. aconitus and An. maculatus. Only 3 species were confirmed as vector using ELISA test, i.e. An. sundaicus, An. barbirostris and An. subpictus with sporosoite rates of 4.2%, 2.1% and 0.1% respectively. An. aconitus, a potential malaria vector in Java and in some onther places was not confirmed as vector in Flores yet. The 3 confirmed vectors were also found positive with sporozoites in West Flores and also found predominant in East Flores.

  4. Genetic affinities of the central Indian tribal populations.

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    Gunjan Sharma

    Full Text Available BACKGROUND: The central Indian state Madhya Pradesh is often called as 'heart of India' and has always been an important region functioning as a trinexus belt for three major language families (Indo-European, Dravidian and Austroasiatic. There are less detailed genetic studies on the populations inhabited in this region. Therefore, this study is an attempt for extensive characterization of genetic ancestries of three tribal populations, namely; Bharia, Bhil and Sahariya, inhabiting this region using haploid and diploid DNA markers. METHODOLOGY/PRINCIPAL FINDINGS: Mitochondrial DNA analysis showed high diversity, including some of the older sublineages of M haplogroup and prominent R lineages in all the three tribes. Y-chromosomal biallelic markers revealed high frequency of Austroasiatic-specific M95-O2a haplogroup in Bharia and Sahariya, M82-H1a in Bhil and M17-R1a in Bhil and Sahariya. The results obtained by haploid as well as diploid genetic markers revealed strong genetic affinity of Bharia (a Dravidian speaking tribe with the Austroasiatic (Munda group. The gene flow from Austroasiatic group is further confirmed by their Y-STRs haplotype sharing analysis, where we determined their founder haplotype from the North Munda speaking tribe, while, autosomal analysis was largely in concordant with the haploid DNA results. CONCLUSIONS/SIGNIFICANCE: Bhil exhibited largely Indo-European specific ancestry, while Sahariya and Bharia showed admixed genetic package of Indo-European and Austroasiatic populations. Hence, in a landscape like India, linguistic label doesn't unequivocally follow the genetic footprints.

  5. Congruence of genomic and ethnolinguistic affinities among five tribal populations of Madhya Pradesh (India)

    Indian Academy of Sciences (India)

    Namita Mukherjee; Mitashree Mitra; Madan Chakraborty; Partha P. Majumder

    2000-08-01

    The central Indian state of Madhya Pradesh is home to a large number of tribal populations of diverse linguistic and ethnic backgrounds. With a view to examining how well genomic affinities among tribal populations of this state correspond with their ethnic and linguistic affinities, we analysed DNA samples of individuals drawn from five tribes with diverse, but reasonably well-documented, ethnohistorical and linguistic backgrounds. Each DNA sample was scored at 16 biallelic DNA marker loci. On the basis of these data, genomic affinities among these populations were estimated. We have found an extremely good correspondence between the genomic and ethnolinguistic affinities.

  6. The 1992 Flores Earthquake and the Flores Backthrust

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    Cummins, P. R.; Koulali, A.; Hossen, J.; Latief, H.

    2014-12-01

    The 1992 Flores earthquake (Mw=7.8) occurred on a back arc thrust near the island of Flores, Indonesia, causing widespread coastal uplift and subsidence, and generating a local tsunami with maximum runup height of over 25 meters that killed over 2,000 people. The event has been the subject of numerous publications on its various aspects, including the earthquake source mechanism determined from seismic data, and modelling of inundation and tide gauge study data to study generation of the tsunami. To date, however, no studies have quantitatively assessed the constraints placed on the source mechanism by all the different types of data - seismic, geodetic and tsunami tide gauge waveforms and inundation. The seismic and coastal uplift data provide strong constraints on the location and orientation of the earthquake fault that are inconsistent with most published information on the "Flores Thrust". In this talk we re-examine the constraints on the earthquake fault, and consider these in light of recent GPS and seismicity data, to suggest the existence of an active fault at depth beneath Flores Island itself.

  7. First fossil insectivores from Flores

    NARCIS (Netherlands)

    Hoek Ostende, van den L.W.; Berch, van der G.; Awe Due, R.

    2006-01-01

    The hominid bearing strata from the Liang Bua cave on Flores have yielded a large amount of microvertebrate remains. Among these are three mandibles of shrews, the first record of fossil insectivores from the island. The fossils, representing two different species, are not referable to any of the

  8. The avifauna of Flores (Lesser Sunda Islands)

    NARCIS (Netherlands)

    Mees, G.F.

    2006-01-01

    The avifauna of the island of Flores (Lesser Sunda Islands) is reviewed. Introductory sections, which include a chapter on the history of ornithological discovery, are followed by the main part, a systematic account in which each species and subspecies known from Flores is treated separately. A disc

  9. 1992 Flores Region, Maumere, Indonesia Images

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — On December 12, 1992, a magnitude 7.5 Ms (USGS) earthquake at 05:29 UT occurred in the Flores, Indonesia, region producing a tsunami that reached shore in five...

  10. en flores de ginger (Alpinia purpurata

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    Helga Blanco-Metzler

    2007-01-01

    Full Text Available Se estudió el efecto de 3 condiciones de luz (completa-548,63 W m-2, media luz-280,02 W m-2, sombra-76,38 W m-2, el uso de repelentes (ajo más chile, neem y pichichío y el uso de bolsas de exclusión, en el daño de Cholus pilicauda a las flores de ginger rosado (Alpinia purpurata en una plantación asociada con poró (Erythrina poeppigiana. El embolse de las flores redujo significativamente el número de flores dañadas, independientemente de la intensidad lumínica. No se encontró diferencias entre el número de flores dañadas con el uso de Azatina®flores dañadas. La sombra densa resultó en un mayor número de flores dañadas, seguida por luz completa y la media.

  11. Immunoglobulin allotypes among Taiwan aborigines: evidence of malarial selection could affect studies of population affinity.

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    Schanfield, Moses S; Ohkura, Koji; Lin, Marie; Shyu, Ryhyuan; Gershowitz, Henry

    2002-06-01

    The aborigines of Taiwan represent the indigenous inhabitants of the island at the time of the arrival of the Chinese from the mainland. Linguistically, the aboriginal Taiwanese are related to the Malayo-Polynesian-speaking inhabitants of Indonesia and the Philippines. Three tribes occupied lowland areas while six tribes occupied highland areas. Previous studies indicate that genetic markers associated with malaria occur in lowland populations. Though the GM haplotypes are demonstrated to be very useful in the measure of population affinities, the possibility of malarial selection on this locus could affect studies of population affinity. The present work is a case study to see whether a subdivided insular population under a possible selective load will provide divergent clustering analysis depending on the population sampled. Immunoglobulin allotype (GM and KM) profiles were generated on 230 lowland and 407 highland Taiwan Aborigines from the nine tribes. A highly significant difference in GM haplotype distribution was detected between lowland and highland populations (adjusted G = 69.408, 2 df [degrees of freedom], p < 0.00001). There were no significant differences in KM*1 frequency by altitude. The Taiwan Aboriginal GM and KM frequencies were compared to data from Indonesians, Vietnamese, Thai, Malay, Chinese from Taiwan, and Ryukyu Islanders from Okinawa using cluster analysis. The lowland populations plot among the Thai (N, NC) and Malayan Aborigines. In contrast, the highland and total Taiwan Aborigine samples plot with the Indonesian, Vietnamese, and Malayan Negrito samples. Thus, depending on the populations of Taiwan Aborigines used, different conclusions could be reached. The highland population supports the published linguistic ties; however, the lowland population does not support the linguistic relationship with Indonesian populations but is more closely related to Thai and Malays, or reflects a similar selection history.

  12. Sahara: Barrier or corridor? Nonmetric cranial traits and biological affinities of North African late Holocene populations.

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    Nikita, Efthymia; Mattingly, David; Lahr, Marta Mirazón

    2012-02-01

    The Garamantes flourished in southwestern Libya, in the core of the Sahara Desert ~3,000 years ago and largely controlled trans-Saharan trade. Their biological affinities to other North African populations, including the Egyptian, Algerian, Tunisian and Sudanese, roughly contemporary to them, are examined by means of cranial nonmetric traits using the Mean Measure of Divergence and Mahalanobis D(2) distance. The aim is to shed light on the extent to which the Sahara Desert inhibited extensive population movements and gene flow. Our results show that the Garamantes possess distant affinities to their neighbors. This relationship may be due to the Central Sahara forming a barrier among groups, despite the archaeological evidence for extended networks of contact. The role of the Sahara as a barrier is further corroborated by the significant correlation between the Mahalanobis D(2) distance and geographic distance between the Garamantes and the other populations under study. In contrast, no clear pattern was observed when all North African populations were examined, indicating that there was no uniform gene flow in the region.

  13. Fitopatología en flores

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    Zapata Ángela Cristina

    1999-11-01

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    La generación de nuevos empleos y mayores divisas para el país, han sido los objetivos principales de las empresas dedicadas a la exportación de flores, actividad que ha pasado a ocupar un lugar importante en la economía colombiana; por tal razón, se hace necesario el estudio a fondo de la biología y el control de los patógenos que más afectan este sector de la agricultura ya que uno de los factores limitantes en la producción de flores de corte son las enfermedades causadas por hongos, bacterias, nernatodos y virus.

  14. Tropical Volcanic Soils From Flores Island, Indonesia

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    Hikmatullah

    2010-01-01

    Full Text Available Soils that are developed intropical region with volcanic parent materials have many unique properties, and high potential for agricultural use.The purpose of this study is to characterize the soils developed on volcanic materials from Flores Island, Indonesia,and to examine if the soils meet the requirements for andic soil properties. Selected five soils profiles developed fromandesitic volcanic materials from Flores Island were studied to determine their properties. They were compared intheir physical, chemical and mineralogical characteristics according to their parent material, and climatic characteristicdifferent. The soils were developed under humid tropical climate with ustic to udic soil moisture regimes withdifferent annual rainfall. The soils developed from volcanic ash parent materials in Flores Island showed differentproperties compared to the soils derived from volcanic tuff, even though they were developed from the sameintermediary volcanic materials. The silica contents, clay mineralogy and sand fractions, were shown as the differences.The different in climatic conditions developed similar properties such as deep solum, dark color, medium texture, andvery friable soil consistency. The soils have high organic materials, slightly acid to acid, low to medium cationexchange capacity (CEC. The soils in western region have higher clay content and showing more developed than ofthe eastern region. All the profiles meet the requirements for andic soil properties, and classified as Andisols order.The composition of sand mineral was dominated by hornblende, augite, and hypersthenes with high weatherablemineral reserves, while the clay fraction was dominated by disordered kaolinite, and hydrated halloysite. The soilswere classified into subgroup as Thaptic Hapludands, Typic Hapludands, and Dystric Haplustands

  15. ANALISIS PERIKANAN HUHATE DI PERAIRAN LARANTUKA, FLORES

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    Mohamad Adha Akbar

    2016-11-01

    Full Text Available Informasi mengenai beberapa aspek perikanan huhate sangat diperlukan sebagai bahan untuk perencanaan pengelolaan perikanan yang berkelanjutan. Penelitian ini dilakukan di Larantuka, Flores Timur pada tahun 2014 dengan tujuan untuk menganalisis perikanan huhate sebagai salah satu tulang punggung perikanan TCT. Kegiatan penelitian diprioritaskan pada analisis unit alat tangkap, daerah penangkapan, komposisi hasil tangkapan dan estimasi Total Faktor Produktivitas (TFP perikanan huhate. Basis data pengukuran adalah himpunan  data pendaratan dan observasi lapang. Hasil penelitian menunjukan bahwa karakteristik armada terdiri dari kapal yang terbuat dari fibreglass dengan kisaran bobot kapal 6 - 30 GT. Daerah penangkapan di sekitar perairan Laut Sawu dan Laut Flores. Hasil tangkapan utama didominansi oleh cakalang (Katsuwonus pelamis sebanyak 82%, juwana tuna (Thunnus spp. 17% dan tongkol (Auxis spp. 1% serta hasil tangkapan ikutan lemadang (Coryphaena hippurus dan marlin (Makaira spp. < 1%. Hasil analisis tangkapan per unit upaya (CPUE memberikan nilai rata-rata sebesar 1,1 ton/trip (0,4-1,7 ton/trip dengan nilai tertinggi terjadi pada Februari, sedangkan terendah terjadi pada Januari. Hasil penelitian menunjukkan terdapat hubungan yang signifikan antara tren bulanan CPUE dan nilai TFP.

  16. Y-chromosome and mtDNA genetics reveal significant contrasts in affinities of modern Middle Eastern populations with European and African populations.

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    Danielle A Badro

    Full Text Available The Middle East was a funnel of human expansion out of Africa, a staging area for the Neolithic Agricultural Revolution, and the home to some of the earliest world empires. Post LGM expansions into the region and subsequent population movements created a striking genetic mosaic with distinct sex-based genetic differentiation. While prior studies have examined the mtDNA and Y-chromosome contrast in focal populations in the Middle East, none have undertaken a broad-spectrum survey including North and sub-Saharan Africa, Europe, and Middle Eastern populations. In this study 5,174 mtDNA and 4,658 Y-chromosome samples were investigated using PCA, MDS, mean-linkage clustering, AMOVA, and Fisher exact tests of F(ST's, R(ST's, and haplogroup frequencies. Geographic differentiation in affinities of Middle Eastern populations with Africa and Europe showed distinct contrasts between mtDNA and Y-chromosome data. Specifically, Lebanon's mtDNA shows a very strong association to Europe, while Yemen shows very strong affinity with Egypt and North and East Africa. Previous Y-chromosome results showed a Levantine coastal-inland contrast marked by J1 and J2, and a very strong North African component was evident throughout the Middle East. Neither of these patterns were observed in the mtDNA. While J2 has penetrated into Europe, the pattern of Y-chromosome diversity in Lebanon does not show the widespread affinities with Europe indicated by the mtDNA data. Lastly, while each population shows evidence of connections with expansions that now define the Middle East, Africa, and Europe, many of the populations in the Middle East show distinctive mtDNA and Y-haplogroup characteristics that indicate long standing settlement with relatively little impact from and movement into other populations.

  17. Population Studies of Intact Vitamin D Binding Protein by Affinity Capture ESI-TOF-MS

    Science.gov (United States)

    Borges, Chad R.; Jarvis, Jason W.; Oran, Paul E.; Rogers, Stephen P.; Nelson, Randall W.

    2008-01-01

    Blood plasma proteins with molecular weights greater than approximately 30 kDa are refractory to comprehensive, high-throughput qualitative characterization of microheterogeneity across human populations. Analytical techniques for obtaining high mass resolution for targeted, intact protein characterization and, separately, high sample throughput exist, but efficient means of coupling these assay characteristics remain rather limited. This article discusses the impetus for analyzing intact proteins in a targeted manner across populations and describes the methodology required to couple mass spectrometric immunoassay with electrospray ionization mass spectrometry for the purpose of qualitatively characterizing a prototypical large plasma protein, vitamin D binding protein, across populations. PMID:19137103

  18. Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow.

    Science.gov (United States)

    Saha, Anjana; Sharma, Swarkar; Bhat, Audesh; Pandit, Awadesh; Bamezai, Ramesh

    2005-01-01

    Four binary polymorphisms and four multiallelic short tandem repeat (STR) loci from the nonrecombining region of the human Y-chromosome were typed in different Indian population groups from Uttar Pradeh (UP), Bihar (BI), Punjab (PUNJ), and Bengal (WB) speaking the Indo-Aryan dialects and from South India (SI) with the root in the Dravidian language. We identified four major haplogroups [(P) 1+, (C and F) 2+, (R1a) 3, (K) 26+] and 114 combinations of Y-STR haplotypes. Analyses of the haplogroups indicated no single origin from any lineage but a result of a conglomeration of different lineages from time to time. The phylogenetic analyses indicate a high degree of population admixture and a greater genetic proximity for the studied population groups when compared with other world populations.

  19. Flores hominid: new species or microcephalic dwarf?

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    Martin, Robert D; Maclarnon, Ann M; Phillips, James L; Dobyns, William B

    2006-11-01

    The proposed new hominid "Homo floresiensis" is based on specimens from cave deposits on the Indonesian island Flores. The primary evidence, dated at approximately 18,000 y, is a skull and partial skeleton of a very small but dentally adult individual (LB1). Incomplete specimens are attributed to eight additional individuals. Stone tools at the site are also attributed to H. floresiensis. The discoverers interpreted H. floresiensis as an insular dwarf derived from Homo erectus, but others see LB1 as a small-bodied microcephalic Homo sapiens. Study of virtual endocasts, including LB1 and a European microcephalic, purportedly excluded microcephaly, but reconsideration reveals several problems. The cranial capacity of LB1 ( approximately 400 cc) is smaller than in any other known hominid < 3.5 Ma and is far too small to derive from Homo erectus by normal dwarfing. By contrast, some associated tools were generated with a prepared-core technique previously unknown for H. erectus, including bladelets otherwise associated exclusively with H. sapiens. The single European microcephalic skull used in comparing virtual endocasts was particularly unsuitable. The specimen was a cast, not the original skull (traced to Stuttgart), from a 10-year-old child with massive pathology. Moreover, the calotte does not fit well with the rest of the cast, probably being a later addition of unknown history. Consideration of various forms of human microcephaly and of two adult specimens indicates that LB1 could well be a microcephalic Homo sapiens. This is the most likely explanation for the incongruous association of a small-brained recent hominid with advanced stone tools.

  20. Genetic structure of Rajaka caste and affinities with other caste populations of Andhra Pradesh, India.

    Science.gov (United States)

    Parvatheesam, C; Babu, B V; Babu, M C

    1997-01-01

    The present study gives an account of the genetic structure in terms of distribution of a few genetic markers, viz., A1A2B0, Rh(D), G6PD deficiency and haemoglobin among the Rajaka caste population of Andhra Pradesh, India. The genetic relationships of the Rajaka caste with other Andhra caste populations were investigated in terms of genetic distance, i.e., Sq B (mn) of Balakrishnan and Sanghvi. Relatively lesser distance was established between the Rajaka and two Panchama castes. Also, the pattern of genetic distance corroborates the hierarchical order of the Hindu varna system.

  1. Genetic and linguistic affinities between human populations in Eurasia and West Africa.

    Science.gov (United States)

    Nettle, Daniel; Harriss, Louise

    2003-06-01

    This study examines the relationship between genetic distance and linguistic affiliation for five regional sets of populations from Eurasia and West Africa. Human genetic and linguistic diversity have been proposed to be generally correlated, either through a direct link, whereby linguistic and genetic affiliations reflect the same past population processes, or an indirect one, where the evolution of the two types of diversity is independent but conditioned by the same geographical factors. By controlling for proximity, indirect correlations due to common geography are eliminated, and any residual relationships found are likely to reflect common linguistic-genetic processes. Clear relationships between genetic distances and linguistic relatedness are detectable in Europe and East and Central Asia, but not in the Middle East, Southeast Asia, or West Africa. We suggest that linguistic and genetic affiliations will only be correlated under specific conditions, such as where there have been large-scale demic diffusions in the last few thousand years, and relative sedentism in the subsequent period.

  2. Polymorphisms of HLA genes in Western Javanese (Indonesia): close affinities to Southeast Asian populations.

    Science.gov (United States)

    Yuliwulandari, R; Kashiwase, K; Nakajima, H; Uddin, J; Susmiarsih, T P; Sofro, A S M; Tokunaga, K

    2009-01-01

    Identification of human leukocyte antigen (HLA) antigens that are known as the highest polymorphic genes has become a valuable tool for tissue transplantation, platelet transfusion, disease susceptibility or resistance, and forensic and anthropological studies. In the present study, the allele and haplotype frequencies of HLA-A, HLA-B, and HLA-DRB1 were studied in 237 unrelated healthy Western Javanese (Indonesia) by the high-resolution polymerase chain reaction-Luminex method. A total of 18 A, 40 B, and 20 DRB1 alleles were identified. The most frequent HLA-A, -B, and -DRB1 alleles were HLA-A*2407 (21.6%), HLA-B*1502 (11.6%) and HLA-B*1513 (11.2%), and DRB1*1202 (37.8%), respectively. The most frequent two-locus haplotypes were HLA-A*2407-B*3505 (7%) and HLA-B*1513-DRB1*1202 (9.2%), and three-locus haplotypes were HLA-A*3401-B*1521-DRB1*150201 (4.6%), HLA-A*2407-B*3505-DRB1*1202 (4.3%), and HLA-A*330301-B*440302-DRB1*070101 (4.2%). HLA allele and haplotype frequencies in addition to phylogenetic tree and principal component analyses based on the four-digit sequence-level allele frequencies for HLA-A, HLA-B, and HLA-DRB1 showed that Western Javanese (Indonesia) was closest to Southeast Asian populations.

  3. Magmatic Evolution of the Western Azores Islands (Corvo and Flores)

    Science.gov (United States)

    Larrea, P.; Galé, C.; Ubide, T.; Widom, E.; Lago, M.; França, Z.; Tierz, P.

    2012-12-01

    Corvo and Flores islands belong to the western group of the Azores archipelago, to the west of the Mid-Atlantic Ridge. Several studies have proposed a common magmatic evolution for both islands. However, most of these studies focus on other Azorean islands. In order to investigate the processes that control the evolution of Corvo and Flores we have studied representative samples of the whole volcanostratigraphical sequence in both islands, including lava flows and dikes. Similarly to other oceanic islands, Corvo and Flores are made up of an alternation of porphyritic rocks and microlitic rocks. The former are picrobasalts and basalts with 5 to 60 volume fraction of large (2-15 mm), primitive antecrysts of olivine, clinopyroxene and plagioclase. The latter are Mg-poor hawaites to trachytes. The Mg-rich composition of the porphyritic rocks is due to the accumulation of primitive antecrysts within a more evolved groundmass. In contrast, the composition of the microlitic rocks provides information on the differentiation processes that controlled the evolution of both islands. The microlitic rocks present holocrystalline to hypocrystalline textures with a mineral assemblage mainly composed of microcrysts of plagioclase, olivine, clinopyroxene opaque minerals and accessory amphibole and apatite. Their major element whole rock composition can be best modeled by a polybaric fractional crystallization process (MELTS software) starting at 500 MPa with cooling steps of 5 degrees Celsius and a water content of 1 %, starting from the most primitive analyzed microlitic rock (MgO: 9.04%; Cr: 630 ppm; Ni: 200 ppm). Hence, we confirm that both islands derived from a common primary magma. The crystallization of the antecrysts included in the porphyritic rocks was probably related to the initial stages of the differentiation process. On the other hand, the microlitic rocks and the groundmass of the porphyritic rocks are related to the residual melts of the polybaric fractional

  4. Age and context of the oldest known hominin fossils from Flores

    DEFF Research Database (Denmark)

    Brumm, Adam; van den Bergh, Gerrit D.; Storey, Michael

    2016-01-01

    Recent excavations at the early Middle Pleistocene site of Mata Menge in the So'a Basin of central Flores, Indonesia, have yielded hominin fossils attributed to a population ancestral to Late Pleistocene Homo floresiensis. Here we describe the age and context of the Mata Menge hominin specimens...... and associated archaeological findings. The fluvial sandstone layer from which the in situ fossils were excavated in 2014 was deposited in a small valley stream around 700 thousand years ago, as indicated by 40Ar/39 Ar and fission track dates on stratigraphically bracketing volcanic ash and pyroclastic density...... current deposits, in combination with coupled uranium-series and electron spin resonance dating of fossil teeth. Palaeoenvironmental data indicate a relatively dry climate in the So'a Basin during the early Middle Pleistocene, while various lines of evidence suggest the hominins inhabited a savannah...

  5. Genetic structure of four socio-culturally diversified caste populations of southwest India and their affinity with related Indian and global groups

    Directory of Open Access Journals (Sweden)

    Rajkumar Revathi

    2004-08-01

    Full Text Available Abstract Background A large number of microsatellites have been extensively used to comprehend the genetic diversity of different global groups. This paper entails polymorphism at 15 STR in four predominant and endogamous populations representing Karnataka, located on the southwest coast of India. The populations residing in this region are believed to have received gene flow from south Indian populations and world migrants, hence, we carried out a detailed study on populations inhabiting this region to understand their genetic structure, diversity related to geography and linguistic affiliation and relatedness to other Indian and global migrant populations. Results Various statistical analyses were performed on the microsatellite data to accomplish the objectives of the paper. The heretozygosity was moderately high and similar across the loci, with low average GST value. Iyengar and Lyngayat were placed above the regression line in the R-matrix analysis as opposed to the Gowda and Muslim. AMOVA indicated that majority of variation was confined to individuals within a population, with geographic grouping demonstrating lesser genetic differentiation as compared to linguistic clustering. DA distances show the genetic affinity among the southern populations, with Iyengar, Lyngayat and Vanniyar displaying some affinity with northern Brahmins and global migrant groups from East Asia and Europe. Conclusion The microsatellite study divulges a common ancestry for the four diverse populations of Karnataka, with the overall genetic differentiation among them being largely confined to intra-population variation. The practice of consanguineous marriages might have attributed to the relatively lower gene flow displayed by Gowda and Muslim as compared to Iyengar and Lyngayat. The various statistical analyses strongly suggest that the studied populations could not be differentiated on the basis of caste or spatial location, although, linguistic affinity was

  6. Notes et contributions à la flore de Corse, XXII

    OpenAIRE

    Jeanmonod, Daniel; Schüssel, André

    2008-01-01

    Les "notes" traitent de 66 taxons intéressants dont 9 néophytes nouveaux pour la flore sauvage de l'île: Aloe arborescens, Armoracia rusticana, Chasmanthe bicolor, C. floribunda, Erigeron annuus, Kalanchoe delagoensis, Ludwigia peploides, Securigera varia et Tillaea alata. De nouvelles stations sont données d'une part pour 23 taxons tenus pour "très rares" (RR) dont 7 (Crataegus laevigata, Fumana laevipes, Iris foetidissima, Lonicera japonica, Medicago arborea, Oxalis articulata et Phyllostac...

  7. Actividad antioxidante de flores de Vochysia discolor Mart

    OpenAIRE

    NAJEH M. KHALIL; Petacci, Fernando; Leite, Rafaela R. S.; Silva, Ediany; Souza, Grínia F. de; Oliveira, Rina E. L. de; Costa, Flaviana; Rocha, Vinicius A.; Mendonça Filho,Carlos V

    2006-01-01

    En este estudio fue evaluada la propiedad antioxidante del extracto alcohólico de flores de Vochysia discolor Mart. (Vochysiaceae) por los ensayos de i) decoloración del radical monocatiónico [2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)] (ABTS+) y ii) supresión del ácido hipocloroso por el método del ácido 5-tio-2-nitro-benzóico (TNB). Nuestros resultados muestran, por primera vez, la existencia de propiedades antioxidantes en una especie del género Vochysia, hecho que, debido ...

  8. Projetos de Prefácios de As Flores do Mal, de Charles Baudelaire

    Directory of Open Access Journals (Sweden)

    Charles Baudelaire

    2009-04-01

    Full Text Available RESUMO: O trabalho consiste na tradução dos quatro projetos de prefácios que Baudelaire escreveu para As Flores do Mal, cujos rascunhos foram publicados apenas postumamente. PALAVRAS-CHAVE: Charles Baudelaire, As Flores do Mal, Crítica literária, Poesia, Tradução.

  9. Projetos de Prefácios de As Flores do Mal, de Charles Baudelaire

    OpenAIRE

    Charles Baudelaire; Grace Alves da Paixão

    2009-01-01

    RESUMO: O trabalho consiste na tradução dos quatro projetos de prefácios que Baudelaire escreveu para As Flores do Mal, cujos rascunhos foram publicados apenas postumamente. PALAVRAS-CHAVE: Charles Baudelaire, As Flores do Mal, Crítica literária, Poesia, Tradução.

  10. La pintura de flores de Miguel Parra (1780-1846

    Directory of Open Access Journals (Sweden)

    López Terrada, María José

    2013-06-01

    Full Text Available Although Miguel Parra Abril (Valencia, 1780-Madrid, 1846 is one of the most important Valencian School painters of floral still lifes, this aspect of his work remains little known. The present article addresses this oversight in two ways. First, by offering an overview of his oeuvre as a painter of floral subjects from his student days at the Fine Arts Academy of Valencia through his mature works. Second, by analyzing two heretofore-unpublished floral compositions in relation to his more familiar works, particularly those located in private collections until recent years.Aunque Miguel Parra Abril (Valencia, 1780-Madrid, 1846 es uno de los pintores de flores más importantes de la Escuela valenciana, esta faceta pictórica de su producción es todavía poco conocida. El presente artículo trata de paliar esta situación ofreciendo, en primer lugar, una visión general de su obra como pintor de flores desde su proceso de aprendizaje en la Academia de Bellas Artes valenciana hasta sus composiciones de madurez. En segundo lugar, se presenta el análisis de dos composiciones florales inéditas y su relación con las obras conocidas hasta el momento, especialmente con aquellas que hasta hace pocos años se encontraban en colecciones particulares.

  11. Danko Brncic and the flower-flies Danko Brncic y las moscas de las flores

    Directory of Open Access Journals (Sweden)

    HAMPTON L. CARSON

    2001-03-01

    Full Text Available This is a personal essay commemorating Brncic as a keen naturalist/evolutionist in the best Darwinian sense. His innate curiosity, so important in a scientist, led him to the discovery of cenain unique drosophilid flies in Chile. The life cycle of one species of flower-fly (Drosophila flavopilosa is of special interest. Females oviposit in fresh flowers of a solanaceous plant that is widespread in Chilean valleys. Twenty years of combined ecological and genetic work, carried out on this species, pioneers the use of a highly specialized Drosophila species in the study of population genetics and evolution. Many eco-genetic features are revealed that are important supplements to observations made on the widely-studied generalist species of the genusEs este un ensayo de naturaleza personal, celebrando a Danko Brncic como un natualista y evolucionista de la mejor calidad en la verdadera tradición darwiniana. Su curiosidad inata tan importante para el científico, lo Ilevó a descubrir algunos drosofilideos chilenos con propiedades únicas. Especial interés tiene el ciclo vital de Drosophila flavopilosa, especie adaptada a flores: la hembra deposita sus huevos en las flores de una solanacea ampliamente distribuida en los valles de Chile. Veinte años de investigación geno-ecológica sobre esta especie resultaron en datos pioneros, con el uso de especies altamente especializadas para aclarar cuestiones generales de genética y evolución de poblaciones. Muchos hechos importantes fueron revelados, distintos de aquellos observados en las especies generalistas y ampliamente distribuidas

  12. Epidemiology of Plasmodium infections in Flores Island, Indonesia using real-time PCR.

    Science.gov (United States)

    Kaisar, Maria M M; Supali, Taniawati; Wiria, Aprilianto E; Hamid, Firdaus; Wammes, Linda J; Sartono, Erliyani; Luty, Adrian J F; Brienen, Eric A T; Yazdanbakhsh, Maria; van Lieshout, Lisette; Verweij, Jaco J

    2013-05-24

    DNA-based diagnostic methods have been shown to be highly sensitive and specific for the detection of malaria. An 18S-rRNA-based, real-time polymerase chain reaction (PCR) was used to determine the prevalence and intensity of Plasmodium infections on Flores Island, Indonesia. Microscopy and real-time multiplex PCR for the detection of Plasmodium species was performed on blood samples collected in a population-based study in Nangapanda Flores Island, Indonesia. A total 1,509 blood samples were analysed. Real-time PCR revealed prevalence for Plasmodium falciparum, Plasmodium vivax, and Plasmodium malariae to be 14.5%, 13.2%, and 1.9% respectively. Sub-microscopic parasitaemia were found in more than 80% of all positive cases. The prevalence of P. falciparum and P. vivax was significantly higher in subjects younger than 20 years (p ≤ 0.01). In the present study, among non-symptomatic healthy individuals, anaemia was strongly correlated with the prevalence and load of P. falciparum infections (p ≤ 0.01; p = 0.02) and with the load of P. vivax infections (p = 0.01) as detected with real-time PCR. Subjects with AB blood group tend to have a higher risk of being infected with P. falciparum and P. vivax when compared to other blood groups. The present study has shown that real-time PCR provides more insight in the epidemiology of Plasmodium infections and can be used as a monitoring tool in the battle against malaria. The unsurpassed sensitivity of real-time PCR reveals that sub microscopic infections are common in this area, which are likely to play an important role in transmission and control. Trials number ISRCTN83830814.

  13. The Liang Bua faunal remains: a 95k.yr. sequence from Flores, East Indonesia.

    Science.gov (United States)

    van den Bergh, G D; Meijer, H J M; Due Awe, Rokhus; Morwood, M J; Szabó, K; van den Hoek Ostende, L W; Sutikna, T; Saptomo, E W; Piper, P J; Dobney, K M

    2009-11-01

    Excavations at Liang Bua, a limestone cave on the island of Flores, East Indonesia, have yielded a well-dated archaeological and faunal sequence spanning the last 95k.yr., major climatic fluctuations, and two human species -H. floresiensis from 95 to 17k.yr.(1), and modern humans from 11k.yr. to the present. The faunal assemblage comprises well-preserved mammal, bird, reptile and mollusc remains, including examples of island gigantism in small mammals and the dwarfing of large taxa. Together with evidence from Early-Middle Pleistocene sites in the Soa Basin, it confirms the long-term isolation, impoverishment, and phylogenetic continuity of the Flores faunal community. The accumulation of Stegodon and Komodo dragon remains at the site in the Pleistocene is attributed to Homo floresiensis, while predatory birds, including an extinct species of owl, were largely responsible for the accumulation of the small vertebrates. The disappearance from the sequence of the two large-bodied, endemic mammals, Stegodon florensis insularis and Homo floresiensis, was associated with a volcanic eruption at 17 ka and precedes the earliest evidence for modern humans, who initiated use of mollusc and shell working, and began to introduce a range of exotic animals to the island. Faunal introductions during the Holocene included the Sulawesi warty pig (Sus celebensis) at about 7ka, followed by the Eurasian pig (Sus scrofa), Long-tailed macaque, Javanese porcupine, and Masked palm civet at about 4ka, and cattle, deer, and horse - possibly by the Portuguese within historic times. The Holocene sequence at the site also documents local faunal extinctions - a result of accelerating human population growth, habitat loss, and over-exploitation.

  14. (/sup 3/H)pirenzepine selectively identifies a high affinity population of muscarinic cholinergic receptors in the rat cerebral cortex

    Energy Technology Data Exchange (ETDEWEB)

    Watson, M.; Roeske, W.R.; Yamamura, H.I.

    1982-11-01

    The specific binding of (/sup 3/H)pirenzepine was investigated in homogenates of rat cerebral cortex, cerebellar cortex, and heart. Specific binding of (/sup 3/H)pirenzepine in the cerebral cortex as defined by displacement with atropine sulfate (1..mu..M) was of high affinity (K/sub d/ = 4-10 nM, receptor density = 1.06 pmoles/mg protein), stereoselective, and competitive with drugs specific for the muscarinic receptor. In contrast, few (/sup 3/H)pirenzepine binding sites were demonstrated in cerebellar and heart homogenates.

  15. Cadeia de flores e plantas ornamentais de jardim em Pareci Novo - Rio Grande do Sul

    OpenAIRE

    2002-01-01

    O Rio Grande do Sul, além de ser o Estado que mais consome flores e plantas ornamentais no país, é um dos maiores produtores do Brasil. Essa produção tem aumentado visivelmente nos últimos cinco anos. Recentemente, houve um acréscimo considerável de consumo de flores e plantas ornamentais de jardim. Este trabalho teve como objetivo analisar a produção e a comercialização de uma cadeia de flores e plantas ornamentais de jardim para a região de Pareci Novo, a qual foi escolhida por ser uma das ...

  16. Genetic structure of the Mon-Khmer speaking groups and their affinity to the neighbouring Tai populations in Northern Thailand

    Directory of Open Access Journals (Sweden)

    Seielstad Mark

    2011-06-01

    Full Text Available Abstract Background The Mon-Khmer speaking peoples inhabited northern Thailand before the arrival of the Tai speaking people from southern China in the thirteenth century A.D. Historical and anthropological evidence suggests a close relationship between the Mon-Khmer groups and the present day majority northern Thai groups. In this study, mitochondrial and Y-chromosomal DNA polymorphisms in more than 800 volunteers from eight Mon-Khmer and ten Tai speaking populations were investigated to estimate the degree of genetic divergence between these major linguistic groups and their internal structure. Results A large fraction of genetic variation is observed within populations (about 80% and 90% for mtDNA and the Y-chromosome, respectively. The genetic divergence between populations is much higher in Mon-Khmer than in Tai speaking groups, especially at the paternally inherited markers. The two major linguistic groups are genetically distinct, but only for a marginal fraction (1 to 2% of the total genetic variation. Genetic distances between populations correlate with their linguistic differences, whereas the geographic distance does not explain the genetic divergence pattern. Conclusions The Mon-Khmer speaking populations in northern Thailand exhibited the genetic divergence among each other and also when compared to Tai speaking peoples. The different drift effects and the post-marital residence patterns between the two linguistic groups are the explanation for a small but significant fraction of the genetic variation pattern within and between them.

  17. Providing affinity

    DEFF Research Database (Denmark)

    Guglielmi, Michel; Johannesen, Hl

    2004-01-01

    This paper will introduce a project sourced by an ideas competition called Landmark East England. It was open to anyone with the ability to develop and deliver a visionary idea for a landmark. A sustainable icon representing a new region in England, which comprises Bedfordshire, Cambridgeshire......, Essex, Hertfordshire, Norfolk and Suffolk. Research found that there was a lack of identity or sense of belonging and nothing anchoring people to the region as a whole. Common affinity is somehow forced to the people of East England and thereby we came to the conclusion that a single landmark...... or a series of landmarks would do little to achieve true affinity. Therefore, we based our design strategy in trying to elaborate an alternatereality based on fabulation, virtualization and narratives that we subtly interweaved into architectonic structures (fabric) of the real. We have created plots...

  18. Between the Baltic and Danubian Worlds: the genetic affinities of a Middle Neolithic population from central Poland.

    Directory of Open Access Journals (Sweden)

    Wiesław Lorkiewicz

    Full Text Available For a long time, anthropological and genetic research on the Neolithic revolution in Europe was mainly concentrated on the mechanism of agricultural dispersal over different parts of the continent. Recently, attention has shifted towards population processes that occurred after the arrival of the first farmers, transforming the genetically very distinctive early Neolithic Linear Pottery Culture (LBK and Mesolithic forager populations into present-day Central Europeans. The latest studies indicate that significant changes in this respect took place within the post-Linear Pottery cultures of the Early and Middle Neolithic which were a bridge between the allochthonous LBK and the first indigenous Neolithic culture of north-central Europe--the Funnel Beaker culture (TRB. The paper presents data on mtDNA haplotypes of a Middle Neolithic population dated to 4700/4600-4100/4000 BC belonging to the Brześć Kujawski Group of the Lengyel culture (BKG from the Kuyavia region in north-central Poland. BKG communities constituted the border of the "Danubian World" in this part of Europe for approx. seven centuries, neighboring foragers of the North European Plain and the southern Baltic basin. MtDNA haplogroups were determined in 11 individuals, and four mtDNA macrohaplogroups were found (H, U5, T, and HV0. The overall haplogroup pattern did not deviate from other post-Linear Pottery populations from central Europe, although a complete lack of N1a and the presence of U5a are noteworthy. Of greatest importance is the observed link between the BKG and the TRB horizon, confirmed by an independent analysis of the craniometric variation of Mesolithic and Neolithic populations inhabiting central Europe. Estimated phylogenetic pattern suggests significant contribution of the post-Linear BKG communities to the origin of the subsequent Middle Neolithic cultures, such as the TRB.

  19. Between the Baltic and Danubian Worlds: the genetic affinities of a Middle Neolithic population from central Poland.

    Science.gov (United States)

    Lorkiewicz, Wiesław; Płoszaj, Tomasz; Jędrychowska-Dańska, Krystyna; Żądzińska, Elżbieta; Strapagiel, Dominik; Haduch, Elżbieta; Szczepanek, Anita; Grygiel, Ryszard; Witas, Henryk W

    2015-01-01

    For a long time, anthropological and genetic research on the Neolithic revolution in Europe was mainly concentrated on the mechanism of agricultural dispersal over different parts of the continent. Recently, attention has shifted towards population processes that occurred after the arrival of the first farmers, transforming the genetically very distinctive early Neolithic Linear Pottery Culture (LBK) and Mesolithic forager populations into present-day Central Europeans. The latest studies indicate that significant changes in this respect took place within the post-Linear Pottery cultures of the Early and Middle Neolithic which were a bridge between the allochthonous LBK and the first indigenous Neolithic culture of north-central Europe--the Funnel Beaker culture (TRB). The paper presents data on mtDNA haplotypes of a Middle Neolithic population dated to 4700/4600-4100/4000 BC belonging to the Brześć Kujawski Group of the Lengyel culture (BKG) from the Kuyavia region in north-central Poland. BKG communities constituted the border of the "Danubian World" in this part of Europe for approx. seven centuries, neighboring foragers of the North European Plain and the southern Baltic basin. MtDNA haplogroups were determined in 11 individuals, and four mtDNA macrohaplogroups were found (H, U5, T, and HV0). The overall haplogroup pattern did not deviate from other post-Linear Pottery populations from central Europe, although a complete lack of N1a and the presence of U5a are noteworthy. Of greatest importance is the observed link between the BKG and the TRB horizon, confirmed by an independent analysis of the craniometric variation of Mesolithic and Neolithic populations inhabiting central Europe. Estimated phylogenetic pattern suggests significant contribution of the post-Linear BKG communities to the origin of the subsequent Middle Neolithic cultures, such as the TRB.

  20. Genetic affinities between trans-oceanic populations of non-buoyant macroalgae in the high latitudes of the Southern Hemisphere.

    Directory of Open Access Journals (Sweden)

    Ceridwen I Fraser

    Full Text Available Marine biologists and biogeographers have long been puzzled by apparently non-dispersive coastal taxa that nonetheless have extensive transoceanic distributions. We here carried out a broad-scale phylogeographic study to test whether two widespread Southern Hemisphere species of non-buoyant littoral macroalgae are capable of long-distance dispersal. Samples were collected from along the coasts of southern Chile, New Zealand and several subAntarctic islands, with the focus on high latitude populations in the path of the Antarctic Circumpolar Current or West Wind Drift. We targeted two widespread littoral macroalgal species: the brown alga Adenocystisutricularis (Ectocarpales, Heterokontophyta and the red alga Bostrychiaintricata (Ceramiales, Rhodophyta. Phylogenetic analyses were performed using partial mitochondrial (COI, chloroplast (rbcL and ribosomal nuclear (LSU / 28S DNA sequence data. Numerous deeply-divergent clades were resolved across all markers in each of the target species, but close phylogenetic relationships - even shared haplotypes - were observed among some populations separated by large oceanic distances. Despite not being particularly buoyant, both Adenocystisutricularis and Bostrychiaintricata thus show genetic signatures of recent dispersal across vast oceanic distances, presumably by attachment to floating substrata such as wood or buoyant macroalgae.

  1. Eddies spatial variability at Makassar Strait – Flores Sea

    Science.gov (United States)

    Nuzula, F.; Syamsudin, M. L.; Yuliadi, L. P. S.; Purba, N. P.; Martono

    2017-01-01

    This study was aimed to get the distribution of eddies spatially and temporally from Makassar Waters (MW) to Flores Sea (FS), as well as its relations with the upwelling, the downwelling, and chlorophyll-a concentration. The study area extends from 115º–125º E to 2.5º–8º S. The datasets were consisted of monthly geostrophic currents, sea surface heights, sea surface temperatures, and chlorophyll-a from 2008 – 2012. The results showed that eddies which found at Makassar Strait (MS) has the highest diameter and speed of 255.3 km and 21.4 cm/s respectively, while at the southern MW has 266.4 km and 15.6 cm/s, and at FS has 182.04 km and 11.4 cm/s. From a total of 51 eddies found, the majority of eddies type was anticyclonic. At MS and FS, eddies formed along the year, whereas at southern MW were found missing in West Season. Moreover, the chlorophyll-a concentration was consistently higher at the eddies area. Even though, the correlation among eddies and the upwelling downwelling phenomena was not significantly as shown by sea surface temperatures value.

  2. Brugia timori INFECTION IN LEKEBAI, FLORES: clinical aspects

    Directory of Open Access Journals (Sweden)

    Arbain Joesoef

    2012-09-01

    Full Text Available Pengamatan filariasis pada penduduk Nualolo-Lekebai, Pulau Flores telah dilakukan pada bulan Februari 1975. Kampung Nualolo-Lekebai berpenduduk 680 jiwa, pekerjaan bertani dan menganut agama Nasrani. Kebiasaan hidup di antara penduduk di daerah ini adalah menyerahkan pelaksanaan pekerjaan berat pada kaum wanita, baik di rumah ataupun di kebun. Dalam perjalanan jauh baik ke kebun atau ke pasar, kaum wanitanya selalu berjalan kaki sedangkan kaum prianya menunggang kuda. Sejumlah 80% dari penduduk kampung ini telah diperiksa terhadap infeksi parasit filaria dan terhadap gejala filariasis. Dari hasil yang ditemukan ternyata penduduk kampung ini menderita infeksi Brugia timori dengan angka derajat infeksi sebesar 7.0% dan angka derajat elephantiasis sebesar 10.3%. Hal yang menarik yang ditemukan dalam pengamatan ini adalah tingginya angka derajat elephantiasis pada kaum wanita dibandingkan dengan pada kaum pria. Fenomena ini mungkin disebabkan oleh kebiasaan hidup kaum wanita di daerah ini sehari-hari yang bekerja lebih berat dan berjalan kaki lebih sering dan lebih jauh dibandingkan kaum prianya.

  3. Age and context of the oldest known hominin fossils from Flores.

    Science.gov (United States)

    Brumm, Adam; van den Bergh, Gerrit D; Storey, Michael; Kurniawan, Iwan; Alloway, Brent V; Setiawan, Ruly; Setiyabudi, Erick; Grün, Rainer; Moore, Mark W; Yurnaldi, Dida; Puspaningrum, Mika R; Wibowo, Unggul P; Insani, Halmi; Sutisna, Indra; Westgate, John A; Pearce, Nick J G; Duval, Mathieu; Meijer, Hanneke J M; Aziz, Fachroel; Sutikna, Thomas; van der Kaars, Sander; Flude, Stephanie; Morwood, Michael J

    2016-06-09

    Recent excavations at the early Middle Pleistocene site of Mata Menge in the So'a Basin of central Flores, Indonesia, have yielded hominin fossils attributed to a population ancestral to Late Pleistocene Homo floresiensis. Here we describe the age and context of the Mata Menge hominin specimens and associated archaeological findings. The fluvial sandstone layer from which the in situ fossils were excavated in 2014 was deposited in a small valley stream around 700 thousand years ago, as indicated by (40)Ar/(39)Ar and fission track dates on stratigraphically bracketing volcanic ash and pyroclastic density current deposits, in combination with coupled uranium-series and electron spin resonance dating of fossil teeth. Palaeoenvironmental data indicate a relatively dry climate in the So'a Basin during the early Middle Pleistocene, while various lines of evidence suggest the hominins inhabited a savannah-like open grassland habitat with a wetland component. The hominin fossils occur alongside the remains of an insular fauna and a simple stone technology that is markedly similar to that associated with Late Pleistocene H. floresiensis.

  4. Flora de capões e hymenoptera (abelhas e vespas) visitantes de flores no Pantanal do Miranda-Abobral

    OpenAIRE

    Boff, Samuel Vieira

    2008-01-01

    Foram estudadas ao longo de 12 meses as abelhas e vespas visitantes de flores em vegetação da borda de 10 capões nas sub-regiões de Miranda-Abobral, Pantanal. As abelhas e vespas que coletaram recursos nessas flores foram coletadas e identificadas. Foi estudada também a biologia floral, bem como os visitantes florais (abelhas e vespas) associados às flores de Couepia uiti (Chrysobalanaceae), trazendo notas sobre freqüência de visitas às flores, bem como sobre o comportamento durante as visita...

  5. Affinity driven social networks

    Science.gov (United States)

    Ruyú, B.; Kuperman, M. N.

    2007-04-01

    In this work we present a model for evolving networks, where the driven force is related to the social affinity between individuals of a population. In the model, a set of individuals initially arranged on a regular ordered network and thus linked with their closest neighbors are allowed to rearrange their connections according to a dynamics closely related to that of the stable marriage problem. We show that the behavior of some topological properties of the resulting networks follows a non trivial pattern.

  6. Incidencia de infecciones quiescentes de Botrytis cinerea en flores y

    Directory of Open Access Journals (Sweden)

    MolinaG. Gilma Sandra

    2004-12-01

    Full Text Available

    Se aisló Botrytis cinerea de flores y frutos asintomáticos de mora de castilla ( Rubus glaucus Benth. en  seis estados fenológicos desde botón cerrado hasta fruto maduro. Estas infecciones quiescentes ocurrieron raramente en botones florales cerrados, pero cuando éstos abren las estructuras florales aparecen colonizadas. La alta frecuencia de infecciones quiescentes en frutos en desarrollo y frutos maduros es atribuible a infecciones tempranas en estructuras florales. Inoculaciones hechas con conidias de B. cinerea marcadas con calcofluor produjeron infecciones en todos los estados fenológicos; la germinación de conidias en los seis estados fenológicos se inició a las 10 horas después de

  7. LA RIQUEZA DE LAS PLANTAS CON FLORES DE COLOMBIA

    Directory of Open Access Journals (Sweden)

    J. ORLANDO RANGEL-CH.

    2015-01-01

    Full Text Available Con base en los inventarios florísticos a nivel regional que se adelantan desde 1991 se documentaron los patrones de riqueza (distribución, concentración a nivel de familia de las plantas con flores en Colombia y en sus regiones naturales extra-andinas. En Colombia están representadas 238 de las 414 familias de plantas con flores reconocidas a nivel global, lo cual significa el 57.7% de esta riqueza. De las regiones naturales incluidas en este estudio, la Amazonia es la más rica en número de especies y la de mayor superficie y en el Caribe se alcanzó el mayor número de familias (201. El índice de riqueza a nivel de familia fue mayor en el Caribe (15.6 x 10-4 y el de especies fue mayor en el Chocó (3.4x10-2 y menor en la Orinoquia (1.7x 10-2.. En la Orinoquia están ausentes 65 familias, en la Amazonia 49, en el Chocó 59 y en el Caribe 35 respectivamente. En cuanto a distintividad taxonómica a nivel de familias, en el Caribe se encuentran 19 familias con distribución restringida, en Amazonia cinco, en el Chocó y en la Orinoquia una en cada caso. No se comprobó una relación directa entre superficie del área de la región natural y las expresiones de la riqueza y de la distintividad taxonómica. Se confirma el patrón alto de riqueza en un número reducido de familias, en las 50 familias más ricas en todas las regiones naturales se concentran los valores de riqueza específica por encima del 82%. Entre las familias con mayor concentración de especies en Colombia, en comparación con la situación a nivel del mundo cabe destacar a Metteniusaceae, grupo que presenta siete de las nueve especies registradas en el mundo e igualmente a Brunelliaceae, Siparunaceae, Cyclanthaceae, Heliconiaceae, Myristicaceae, Marcgraviaceae, Gunneraceae, Humiriaceae, Rapateaceae y Tropaeolaceae. Una comparación de los patrones de riqueza a nivel de familia en los países megadiversos de Suramérica, muestra que en Brasil 41 familias tienen mayor n

  8. Raja Servus of Larantuka, Flores, Eastern Indonesia Le raja Servus de Larantuka, à Flores, en Indonésie orientale

    Directory of Open Access Journals (Sweden)

    Robert H. Barnes

    2012-07-01

    Full Text Available The Dutch deposed Raja Lorenzo II of Larantuka, Flores, in 1904 and exiled him to Java. After his son Servus reached maturity, they appointed him Raja. By then the office had largely been reduced to a principally administrative function at the bottom of the colonial bureaucracy, although the Dutch called the rajas in the Dutch East Indies “self-governors”.Servus seems to have been demoralized by an attack on his life which he survived only after six hours of swimming in the sea. Eventually both the Dutch officials and the local Catholic missionaries became dissatisfied with him and he was forced to resign. Later the Dutch were forced to leave and the Indonesian state completed the job of bureaucratizing local administration by abolishing the office of raja.Les Hollandais ont déposé le raja Lorenzo II de Larantuka en 1904 et l’ont exilé à Java. Lorsque son fils Servus a atteint sa maturité, ils l’ont nommé raja. Alors, le poste avait été largement réduit à une fonction surtout administrative au bas de la bureaucratie coloniale, même si les Hollandais appelaient les rajas des Indes orientales Hollandaises « gouverneurs autonomes ». Servus semble avoir perdu le moral après une agression à laquelle il ne survécut qu’après une nage de six heures dans la mer. Au final, il déçut à la fois les fonctionnaires hollandais et les missionnaires catholiques locaux qui l’obligèrent à démissionner. Par la suite, les Hollandais furent contraints au départ et l’état indonésien termina le travail de bureaucratisation de l’administration locale en mettant fin à la fonction de raja.

  9. PRODUCCIÓN DE FLORES EN LA AGRICULTURA URBANA DE SAN JOSÉ DE LAS LAJAS, CUBA

    Directory of Open Access Journals (Sweden)

    Ania Yong Chou

    2014-01-01

    Full Text Available El creciente aumento en el consumo de flores en el municipio San José de las Lajas ha provocado que se incluyan nuevas especies de flores de corte en los sistemas agrícolas, y con ello nuevas tecnologías de manejo. La capacitación in situ de los agricultores, facilitada por investigadores y por productores con mayor experiencia en este renglón productivo, fue llevada a cabo a través de talleres participativos y visitas de intercambio. Se consiguió incrementar la diversidad en tres especies (clavel chino, rosa y nardo y se identificaron seis experimentos diseñados y conducidos por los productores y relacionados con la introducción de especies de flores, asociaciones y rotaciones, arreglos espaciales y conservación de semilla.

  10. The origins and persistence of Homo floresiensis on Flores: biogeographical and ecological perspectives

    Science.gov (United States)

    Dennell, Robin W.; Louys, Julien; O'Regan, Hannah J.; Wilkinson, David M.

    2014-07-01

    The finding of archaeological evidence predating 1 Ma and a small hominin species (Homo floresiensis) on Flores, Indonesia, has stimulated much research on its origins and ancestry. Here we take a different approach and examine two key questions - 1) how did the ancestors of H. floresiensis reach Flores and 2) what are the possibilities for estimating the likelihood of hominin persistence for over 1 million years on a small island? With regard to the first question, on the basis of the biogeography we conclude that the mammalian, avian, and reptilian fauna on Flores arrived from a number of sources including Java, Sulawesi and Sahul. Many of the terrestrial taxa were able to float or swim (e.g. stegodons, giant tortoises and the Komodo dragon), while the rodents and hominins probably accidentally rafted from Sulawesi, following the prevailing currents. The precise route by which hominins arrived on Flores cannot at present be determined, although a route from South Asia through Indochina, Sulawesi and hence Flores is tentatively supported on the basis of zoogeography. With regards to the second question, we find the archaeological record equivocal. A basic energetics model shows that a greater number of small-bodied hominins could persist on Flores than larger-bodied hominins (whether H. floresiensis is a dwarfed species or a descendent of an early small-bodied ancestor is immaterial here), which may in part explain their apparent long-term success. Yet the frequent tsunamis and volcanic eruptions in the region would certainly have affected all the taxa on the island, and at least one turnover event is recorded, when Stegodon sondaari became extinct. The question of the likelihood of persistence may be unanswerable until we know much more about the biology of H. floresiensis.

  11. A small skull from Flores dated to the 20th century

    DEFF Research Database (Denmark)

    Villa, Chiara; Persson, Liselott; Alexandersen, Verner

    2012-01-01

    A human skull with mandible from the Ngada District on the island of Flores, Indonesia, is described in order to contribute to the knowledge of variation in cranial architecture, which is important in interpretations of evolutionary cerebralisation. The skull was excavated in 1924 and sent...... to the National Museum in Copenhagen. The "Copenhagen Flores" (CF) male skull is radiocarbon-dated and of modern age. The cranium is small, but larger than e.g. Liang Bua skull (LB1) in every measurement. The (CT-scan based) cranial capacity of 1258 ml is normal for modern humans, but somewhat lower than values...

  12. Características de flores, néctar y visitantes de Kerianthera preclara (Rubiaceae)

    OpenAIRE

    MARQUES-SOUZA,Antonio Carlos; Absy, María Lúcia; Miranda, Ires Pauta de A; Küchmeister, Heike E C

    2016-01-01

    Se observó el crecimiento del tubo corolar, la producción de néctar y los visitantes en las flores de Keriant hera preclara Kirkibride (Rubiaceae). Se constató que el desárrollo del tubo de la corola duró de siete a ocho semanas hasta su apenura. Los principales visitantes en las flores fueron abejas sin aguijón (Apidae: Meliponinae), colibries (Trochilidae), avispas (Vespidae), hormigas (Formicidae) y algunos curculiónidos (Curculionidae). La abeja Trigona willana fue la única que además del...

  13. Evolved developmental homeostasis disturbed in LB1 from Flores, Indonesia, denotes Down syndrome and not diagnostic traits of the invalid species Homo floresiensis

    Science.gov (United States)

    Henneberg, Maciej; Eckhardt, Robert B.; Chavanaves, Sakdapong; Hsü, Kenneth J.

    2014-08-01

    Human skeletons from Liang Bua Cave, Flores, Indonesia, are coeval with only Homo sapiens populations worldwide and no other previously known hominins. We report here for the first time to our knowledge the occipitofrontal circumference of specimen LB1. This datum makes it possible to link the 430-mL endocranial volume of LB1 reported by us previously, later confirmed independently by other investigators, not only with other human skeletal samples past and present but also with a large body of clinical data routinely collected on patients with developmental disorders. Our analyses show that the brain size of LB1 is in the range predicted for an individual with Down syndrome (DS) in a normal small-bodied population from the geographic region that includes Flores. Among additional diagnostic signs of DS and other skeletal dysplasiae are abnormally short femora combined with disproportionate flat feet. Liang Bua Cave femora, known only for LB1, match interlimb proportions for DS. Predictions based on corrected LB1 femur lengths show a stature normal for other H. sapiens populations in the region.

  14. A new subspecies of Accipiter virgatus (Temminck) from Flores, Lesser Sunda Islands, Indonesia (Aves: Accipitridae)

    NARCIS (Netherlands)

    Mees, G.F.

    1984-01-01

    A new subspecies of Accipiter virgatus (Temminck) is described from Flores (Lesser Sunda Islands). In addition some notes are given on the distribution of A. virgatus in south-eastern Burma and adjacent parts of Thailand, supplementary to an earlier paper (Mees, 1981).

  15. Socio-economic modelling of rabies control in Flores Island, Indonesia

    NARCIS (Netherlands)

    Wera, Ewaldus

    2017-01-01

    Rabies is a zoonotic viral disease that can cause encephalomyelitis both in animals and humans. Since its introduction in Flores Island, Indonesia in 1997, it has been a serious public health threat with significant economic consequences. To control the disease, annual dog vaccination campaigns have

  16. Costs of Rabies Control: An Economic Calculation Method Applied to Flores Island

    NARCIS (Netherlands)

    Wera, E.; Velthuis, A.G.J.; Geong, M.; Hogeveen, H.

    2013-01-01

    Background: Rabies is a zoonotic disease that, in most human cases, is fatal once clinical signs appear. The disease transmits to humans through an animal bite. Dogs are the main vector of rabies in humans on Flores Island, Indonesia, resulting in about 19 human deaths each year. Currently, rabies

  17. Overstated Optimism: Arizona's Structured English Immersion Program under "Horne v. Flores"

    Science.gov (United States)

    Mora, Jill Kerper

    2010-01-01

    This article is an analysis of the educational implications of the Supreme Court (USSC) decision in "Horne v. Flores" (2009). The USSC remanded the Arizona case to the lower court, requiring a rehearing of petitioners' request for relief from the court's oversight of AZ's "structured English immersion" (SEI) program mandated under HB2064. The…

  18. The Court versus Consent Decrees? Schools, "Horne v. Flores" and Judicial Strategies of Institutional Reform Litigation

    Science.gov (United States)

    Chilton, Bradley; Chwialkowski, Paul

    2014-01-01

    Is the U.S. Supreme Court inviting litigants to take aim at unraveling injunctions in institutional reform litigation--especially consent decrees in the schools? In "Horne v. Flores" (2009), the court remanded a 17-year-old school reform case to a federal judge with orders to look beyond consent decrees on financing, reducing class…

  19. "Keeping up the Good Fight": The Said and Unsaid in "Flores v. Arizona"

    Science.gov (United States)

    Thomas, Melinda Hollis; Aletheiani, Dinny Risri; Carlson, David Lee; Ewbank, Ann Dutton

    2014-01-01

    The authors' purpose in this article is to interrogate the mediated and political discourses that emerged alongside the "Flores v. Arizona" case. The authors endeavor to offer another voice, framework and approach that may help sustain a continuous, paramount conversation concerning the educational rights of English language…

  20. The Many Faces of Compliance: The Supreme Court's Decision in "Horne v. Flores"

    Science.gov (United States)

    Thro, William E.

    2009-01-01

    At first blush, the Supreme Court's recent decision in "Horne v. Flores" (2009) appears to be about the proper standard for determining when to modify a previous judgment, a topic that would interest only civil procedure geeks. Yet, on closer examination, "Horne" is about giving local and state officials discretion to solve education problems and,…

  1. Uptake of Rabies Control Measures by Dog Owners in Flores Island, Indonesia

    NARCIS (Netherlands)

    Wera, Ewaldus; Mourits, M.C.M.; Hogeveen, Henk

    2015-01-01

    Rabies has been a serious public health threat in Flores Island, Indonesia since it was introduced in 1997. To control the disease, annual dog vaccination campaigns have been implemented to vaccinate all dogs free of charge. Nevertheless, the uptake rate of the vaccination campaigns has been low.

  2. San José de Flores: parada obligada desde y hacia Buenos Aires.

    Directory of Open Access Journals (Sweden)

    Ulises Camino

    2008-12-01

    Full Text Available The project Prehistoric and colonial period early in the origin of San Jose Flores, examines how these people (by the side of Camino Real, near Buenos Aires city joined the Global System. Here is presented the first data on the archaeological work and a historical synthesis of this Buenos Aires neighborhood, made so far.

  3. Helminth infections on Flores Island, Indonesia : associations with communicable and non-communicable diseases

    NARCIS (Netherlands)

    Wiria, Aprilianto Eddy

    2013-01-01

    In this thesis we reported our investigations of the relationship between soil-transmitted helminths (STH) and a number of outcomes, in particular malaria, insulin resistance (a marker for type-2 diabetes (T2D)) and atherosclerosis (a marker for cardiovascular diseases (CVD)) on Flores island, Indon

  4. Dinâmica floral e abortamento de flores em híbridos de canola e mostarda castanha

    Directory of Open Access Journals (Sweden)

    Rafael Battisti

    2013-02-01

    Full Text Available O objetivo deste trabalho foi avaliar a dinâmica floral e determinar o índice de abortamento de flores de híbridos de canola (Brassica napus e de mostarda castanha (Brassica juncea, bem como determinar suas relações com as condições meteorológicas do Sul do Brasil. Durante a floração, dez híbridos de canola e dois de mostarda foram avaliados a cada três dias quanto ao número de flores abertas, de síliquas e de flores abortadas. O número acumulado e relativo de flores foi usado para avaliação da dinâmica floral. A relação desses números com a soma térmica acumulada durante a floração foi determinada por meio de modelo logístico. A partir dos coeficientes desse modelo, identificaram-se grupos de genótipos com diferentes taxas de emissão de flores. O abortamento de flores entre híbridos variou de 10,53 a 45,96% e correlacionou-se com a temperatura e a demanda evaporativa da atmosfera. Genótipos com maiores tempos térmicos entre o período de máxima emissão de flores e o final da floração geralmente apresentam maiores percentagens de abortamento de flores. O ajuste dos dados de emissão de flores aos de soma térmica do período da floração, por meio de modelo logístico, permite simular a dinâmica floral de híbridos de canola e mostarda castanha.

  5. Biologia floral e fragrâncias das flores de Passiflora L

    OpenAIRE

    Villamil Montero, Daniel Antonio [UNESP

    2013-01-01

    As flores das espécies do gênero Passiflora têm recebido especial atenção por sua extraordinária beleza e complexidade da corola além de suas intensas fragrâncias. A presença de tecidos secretores de compostos voláteis (CVS) nas flores de Passiflora é muito variável, têm grande importância ecológica e prospecção econômica. Atualmente, só se tem registro dos CVs das fragrâncias florais de algumas poucas espécies, obtidos por meio de diferentes metodologias, com resultados variáveis. Durante os...

  6. Biologia floral e fragrâncias das flores de Passiflora L

    OpenAIRE

    Villamil Montero, Daniel Antonio

    2013-01-01

    As flores das espécies do gênero Passiflora têm recebido especial atenção por sua extraordinária beleza e complexidade da corola além de suas intensas fragrâncias. A presença de tecidos secretores de compostos voláteis (CVS) nas flores de Passiflora é muito variável, têm grande importância ecológica e prospecção econômica. Atualmente, só se tem registro dos CVs das fragrâncias florais de algumas poucas espécies, obtidos por meio de diferentes metodologias, com resultados variáveis. Durante os...

  7. Implication de la flore intestinale dans le métabolisme énergétique

    OpenAIRE

    Delzenne, Nathalie M; Cani, Patrice D.

    2008-01-01

    La flore intestinale est aujourd’hui considérée comme un organe à part entière, qui joue un rôle clé dans le métabolisme énergétique. La flore peut en effet augmenter la rentabilité énergétique des aliments ingérés qui ont échappé à la digestion dans la partie haute de l’intestin, via leur fermentation. Par ailleurs, le flux des acides gras et leur stockage adipocytaire sont contrôlés - notamment via le facteur FIAF (fastinginduced adipocyte factor), dont l’expression est tributaire de la pré...

  8. Modelling of historical tsunami in Eastern Indonesia: 1674 Ambon and 1992 Flores case studies

    Science.gov (United States)

    Pranantyo, Ignatius Ryan; Cummins, Phil; Griffin, Jonathan; Davies, Gareth; Latief, Hamzah

    2017-07-01

    In order to reliably assess tsunami hazard in eastern Indonesia, we need to understand how historical events were generated. Here we consider two such events: the 1674 Ambon and the 1992 Flores tsunamis. Firstly, Ambon Island suffered a devastating earthquake that generated a tsunami with 100 m run-up height on the north coast of the island in 1674. However, there is no known active fault around the island capable of generating such a gigantic wave. Rumphius' report describes that the initial wave was coming from three villages that collapsed immediately after the earthquake with width as far as a musket shot. Moreover, a very high tsunami was only observed locally. We suspect that a submarine landslide was the main cause of the gigantic tsunami on the north side of Ambon Island. Unfortunately, there is no data available to confirm if landslide have occurred in this region. Secondly, several tsunami source models for the 1992 Flores event have been suggested. However, the fault strike is quite different compare to the existing Flores back-arc thrust and has not been well validated against a tide gauge waveform at Palopo, Sulawesi. We considered a tsunami model based on Griffin, et al., 2015, extended with high resolution bathymetry laround Palopo, in order to validate the latest tsunami source model available. In general, the model produces a good agreement with tsunami waveforms, but arrives 10 minutes late compared to observed data. In addition, the source overestimates the tsunami inundation west of Maumere, and does not account for the presumed landslide tsunami on the east side of Flores Island.

  9. Very broadband seismic analysis of the 1992 Flores, Indonesia, earthquake (Mw = 7.9)

    Science.gov (United States)

    Beckers, Jos; Lay, Thorne

    1995-09-01

    The December 12, 1992, Flores Island earthquake (Mw = 7.9), which caused a destructive tsunami, is located in the back arc of the transition zone between the Sunda and Banda arcs, a region in active collision with the Australian continental margin. We study the earthquake using four seismological techniques spanning a period range of 1-1000 s and infer that the Flores event may be characterized as a shallow back arc thrust with fault plane strike 70°±30°, dip 28°±10° and rake 80° to 140° (linear trade-off with strike), a rupture consisting of three discrete pulses with a total duration of 70 s (centroid time 26.3 s) and an estimated moment release between 7.5×1020 and 8.0×1020 N m. From the slip vector we infer that compressional forces play an important role in the deformation mechanism of the back arc north of Flores Island. Body waves constrain the hypocentral depth to be 16 km with rupture mainly propagating updip to shallow depth and bilaterally along strike with most subevents located toward the northeast. Evidence for rupture directivity from surface wave deconvolutions is inconclusive, but the overall source function is consistent with body wave results. Our body wave finite fault model is in rough agreement with two models proposed to explain tsunami run-up observations. Normal mode modeling of W phase observations at periods longer than 70 s shows that slow slip is negligible. From this and the slip distribution determined from the body wave analysis we infer that the seismic source is an unlikely candidate to explain anomalously high tsunami run-ups measured on northeastern Flores Island.

  10. Marine algae of the island of Flores, Azores : ecology and floristics

    OpenAIRE

    Tittley, Ian; Neto, Ana I.; Farnham, William F.

    1998-01-01

    Proceedings of the 2nd Symposium of Fauna & Flora of the Atlantic Islands, Las Palmas, Fevereiro 1996. Preliminary results of an extensive field survey of the marine algal flora of Flores are presented. Intertidal and subtidal algal zonation and community structure were investigated by sampling quadrats along transect lines. Intertidal areas were characterised by successive zones of barnacles, algal turf (Gelidium spp., Centroceras clavulatum, Laurencia spp. and other algae), and Corallina...

  11. Homo floresiensis-like fossils from the early Middle Pleistocene of Flores.

    Science.gov (United States)

    van den Bergh, Gerrit D; Kaifu, Yousuke; Kurniawan, Iwan; Kono, Reiko T; Brumm, Adam; Setiyabudi, Erick; Aziz, Fachroel; Morwood, Michael J

    2016-06-09

    The evolutionary origin of Homo floresiensis, a diminutive hominin species previously known only by skeletal remains from Liang Bua in western Flores, Indonesia, has been intensively debated. It is a matter of controversy whether this primitive form, dated to the Late Pleistocene, evolved from early Asian Homo erectus and represents a unique and striking case of evolutionary reversal in hominin body and brain size within an insular environment. The alternative hypothesis is that H. floresiensis derived from an older, smaller-brained member of our genus, such as Homo habilis, or perhaps even late Australopithecus, signalling a hitherto undocumented dispersal of hominins from Africa into eastern Asia by two million years ago (2 Ma). Here we describe hominin fossils excavated in 2014 from an early Middle Pleistocene site (Mata Menge) in the So'a Basin of central Flores. These specimens comprise a mandible fragment and six isolated teeth belonging to at least three small-jawed and small-toothed individuals. Dating to ~0.7 Ma, these fossils now constitute the oldest hominin remains from Flores. The Mata Menge mandible and teeth are similar in dimensions and morphological characteristics to those of H. floresiensis from Liang Bua. The exception is the mandibular first molar, which retains a more primitive condition. Notably, the Mata Menge mandible and molar are even smaller in size than those of the two existing H. floresiensis individuals from Liang Bua. The Mata Menge fossils are derived compared with Australopithecus and H. habilis, and so tend to support the view that H. floresiensis is a dwarfed descendent of early Asian H. erectus. Our findings suggest that hominins on Flores had acquired extremely small body size and other morphological traits specific to H. floresiensis at an unexpectedly early time.

  12. Cuphea melvilla Lindlay (Lythraceae: uma espécie do Cerrado polinizada por beija-flores Cuphea melvilla Lindlay (Lythraceae: a Cerrado species pollinated by hummingbirds

    Directory of Open Access Journals (Sweden)

    Ana Flávia de Oliveira Melazzo

    2012-06-01

    Full Text Available Cuphea melvilla é uma espécie peculiar dentro de um gênero majoritariamente melitófilo. Dois agrupamentos de indivíduos, em bordas das matas de galeria do Córrego do Panga, Uberlândia, MG, foram estudados com o objetivo de investigar o sistema de polinização e sistema de reprodução da espécie na região. O estudo foi realizado de janeiro a junho de 1999. Cuphea melvilla é uma espécie arbustiva com características morfológicas e eventos florais que confirmam sua adaptação à polinização por beija-flores. A floração foi longa, com início em Janeiro, em plena estação chuvosa, e término em Julho, no início da seca. O tubo floral formado pelo hipanto é calcarado na base, onde se acumula o néctar produzido por nectário localizado na base do ovário. As flores são marcadamente protândricas, mas flores em diferentes fases podem ser encontradas nos racemos. Os dados mostraram que a espécie é autocompatível e não apomítica, mas devido à dicogamia marcada, necessita polinização ativa para formar frutos. Phaethornis pretrei, Amazilia fimbriata, Thalurania furcata, Eupetomena macroura e Chlorostilbon lucidus (fêmea foram as espécies de beija-flores observadas visitando e polinizando as flores de C. melvilla. Amazilia fimbriata e C. lucidus apresentaram ocasionalmente comportamento territorial, P. pretrei apresentou forrageamento em linhas de captura, e T. furcata e E. macroura apresentaram forrageamento do tipo oportunístico, visitando as populações estudadas esporadicamente. Amazilia fimbriata, C. lucidus e P. pretrei foram considerados os polinizadores mais importantes, dada a sua constância. As características morfológicas das flores de Cuphea melvilla relacionadas a adaptações aos beija-flores parecem ser derivadas no gênero, sendo que a polinização por beija-flores nas distintas seções indica adaptação convergente a este modo de polinização.Cuphea melvilla is a peculiar species of a mostly

  13. Intention of dog owners to participate in rabies control measures in Flores Island, Indonesia.

    Science.gov (United States)

    Wera, Ewaldus; Mourits, Monique C M; Hogeveen, Henk

    2016-04-01

    The success of a rabies control strategy depends on the commitment and collaboration of dog owners. In this study the theory of planned behaviour (TPB) was used to identify the factors, which are associated with the intention of dog owners to participate in rabies control measures in the Manggarai and Sikka regencies of Flores Island, Indonesia. Questionnaires were administered to 450 dog owners from 44 randomly selected villages in the two regencies. Ninety-six percent of the dog owners intended to participate in a free-of-charge vaccination campaign. The intention decreased to 24% when dog owners were asked to pay a vaccination fee equal to the market price of the vaccine (Rp 18.000 per dose=US$2). Approximately 81% of the dog owners intended to keep their dogs inside their house or to leash them day and night during a period of at least three months in case of an incidence of rabies in the dog population within their village. Only 40% intended to cull their dogs in case of a rabies incident within their village. Using multivariable logistic regression analysis, the attitude item 'vaccinating dogs reduces rabies cases in humans', and the perceived behavioural control items 'availability of time' and 'ability to confine dogs' were shown to be significantly associated with the intention to participate in a free-of-charge vaccination campaign. The attitude item 'culling dogs reduces rabies cases in humans' was significantly associated with the intention to participate in a culling measure. The attitude item 'leashing of dogs reduces human rabies cases' and perceived behavioural controls 'availability of time' and 'money to buy a leash' were associated with the intention to leash dogs during a rabies outbreak. As the attitude variables were often significantly associated with intention to participate in a rabies control measure, an educational rabies campaign focusing on the benefit of rabies control measures is expected to increase the intention of dog owners to

  14. Longevidade pós-colheita de pseudobulbos com flores de Dendrobium nobile (Orchidaceae.

    Directory of Open Access Journals (Sweden)

    Adriane Marinho De Assis

    2003-06-01

    Full Text Available As orquídeas são consideradas plantas ornamentais de grande destaque na floricultura, sendo utilizadas como plantas de vaso e flores de corte. O objetivo deste trabalho foi avaliar a longevidade pós-colheita de pseudobulbos com flores de Dendrobium nobile, pelo uso de soluções conservantes, contendo diferentes concentrações de sacarose. Os tratamentos realizados foram: T1 água destilada; T2 sem água; T3 10gL-1 de sacarose; T4 20gL-1 de sacarose; T5 30gL-1 de sacarose; T6 40gL-1 de sacarose; T7 80gL-1 de sacarose. A longevidade foi avaliada empregando-se o critério de notas. O delineamento experimental adotado foi o inteiramente casualizado, com sete tratamentos e dez repetições.As flores apresentaram longevidade de dez dias, a qual não foi influenciada pela utilização de soluções conservantes contendo sacarose.

  15. On affine rigidity

    CERN Document Server

    Gortler, Steven J; Liu, Ligang; Thurston, Dylan P

    2010-01-01

    We study the properties of affine rigidity of a hypergraph and prove a variety of fundamental results. First, we show that affine rigidity is a generic property (i.e., depends only on the hypergraph, not the particular embedding). Then we prove that a graph is generically neighborhood affinely rigid in d-dimensional space if it is (d+1)-vertex-connected. We also show neighborhood affine rigidity of a graph implies universal rigidity of its squared graph. Our results, and affine rigidity more generally, have natural applications in point registration and localization, as well as connections to manifold learning.

  16. On affine rigidity

    Directory of Open Access Journals (Sweden)

    Steven J. Gortler

    2013-12-01

    Full Text Available We study the properties of affine rigidity of a hypergraph and prove a variety of fundamental results. First, we show that affine rigidity is a generic property (i.e., depends only on the hypergraph, not the particular embedding. Then we prove that a graph is generically neighborhood affinely rigid in d-dimensional space if it is (d+1-vertex-connected. We also show neighborhood affine rigidity of a graph implies universal rigidity of its squared graph.  Our results, and affine rigidity more generally, have natural applications in point registration and localization, as well as connections to manifold learning.

  17. The antiphasic regulatory module comprising CDF5 and its antisense RNA FLORE links the circadian clock to photoperiodic flowering.

    Science.gov (United States)

    Henriques, Rossana; Wang, Huan; Liu, Jun; Boix, Marc; Huang, Li-Fang; Chua, Nam-Hai

    2017-07-31

    Circadian rhythms of gene expression are generated by the combinatorial action of transcriptional and translational feedback loops as well as chromatin remodelling events. Recently, long noncoding RNAs (lncRNAs) that are natural antisense transcripts (NATs) to transcripts encoding central oscillator components were proposed as modulators of core clock function in mammals (Per) and fungi (frq/qrf). Although oscillating lncRNAs exist in plants, their functional characterization is at an initial stage. By screening an Arabidopsis thaliana lncRNA custom-made array we identified CDF5 LONG NONCODING RNA (FLORE), a circadian-regulated lncRNA that is a NAT of CDF5. Quantitative real-time RT-PCR confirmed the circadian regulation of FLORE, whereas GUS-staining and flowering time evaluation were used to determine its biological function. FLORE and CDF5 antiphasic expression reflects mutual inhibition in a similar way to frq/qrf. Moreover, whereas the CDF5 protein delays flowering by directly repressing FT transcription, FLORE promotes it by repressing several CDFs (CDF1, CDF3, CDF5) and increasing FT transcript levels, indicating both cis and trans function. We propose that the CDF5/FLORE NAT pair constitutes an additional circadian regulatory module with conserved (mutual inhibition) and unique (function in trans) features, able to fine-tune its own circadian oscillation, and consequently, adjust the onset of flowering to favourable environmental conditions. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  18. Affine Dynamics with Torsion

    CERN Document Server

    Gultekin, Kemal

    2015-01-01

    In this study, we give a thorough analysis of a general affine gravity with torsion. After a brief exposition of the affine gravities considered by Eddington and Schroedinger, we construct and analyze different affine gravities based on determinants of the Ricci tensor, torsion tensor, Riemann tensor and their combinations. In each case we reduce equations of motion to their simplest forms and give a detailed analysis of their solutions. Our analyses lead to construction of the affine connection in terms of curvature and torsion tensors. Our solutions of the dynamical equations show that curvature tensors at different points are correlated via non-local, exponential rescaling factors determined by the torsion tensor.

  19. Exploration of Ulumbu geothermal field, Flores-east nusa tenggara, Indonesia

    Energy Technology Data Exchange (ETDEWEB)

    Sulasdi, Didi

    1996-01-26

    This paper describes the progress made in developing geothermal resources at Ulumbu Flores, Indonesia for utilization mini geothermal power generation. Two deep exploratory wells drilling drilled by PLN confirmed the existence of the resources. The well measurement carried out during drilling and after completion of the well indicated that the major permeable zone at around 680 m depth and that this zone is a steam cap zone, which is likely to produce high enthalpy steam. The above information indicates that well ULB-01 will produce a mass flow at least 40 tonnes per hour, which will ensure a 3 MW (E) Ulumbu mini geothermal power plant.

  20. Continuous affine processes

    DEFF Research Database (Denmark)

    Buchardt, Kristian

    2016-01-01

    Affine processes possess the property that expectations of exponential affine transformations are given by a set of Riccati differential equations, which is the main feature of this popular class of processes. In this paper we generalise these results for expectations of more general transformati...

  1. Axioms of affine buildings

    OpenAIRE

    Schwer, Petra N.

    2009-01-01

    We prove equivalence of certain axiom sets for affine buildings. Along the lines a purely combinatorial proof of the existence of a spherical building at infinity is given. As a corollary we obtain that ``being an affine building'' is independent of the metric structure of the space.

  2. Aplicabilidade do termo antocrono para representar a velocidade de abertura de flores em inflorescência

    Directory of Open Access Journals (Sweden)

    Natalia Teixeira Schwab

    2014-09-01

    Full Text Available O objetivo deste trabalho foi propor um termo para representar o intervalo de tempo de abertura entre flores sucessivas em inflorescências, e verificar a aplicabilidade deste termo a gladíolo de corte. O termo foi construído pela junção dos radicais gregos anto- (antos = flor e crono- (cronos = tempo, para corresponder ao tempo necessário para a abertura de flores sucessivas em ramos florais (inflorescências, tendo-se como unidade o tempo por flor. Para testar o conceito e a aplicabilidade do termo, dados do número acumulado de floretes abertos em espigas de gladíolo foram coletados em dois experimentos de campo, em Santa Maria, RS, de agosto de 2011 a novembro de 2013. Para cada parcela de seis plantas, realizou-se uma regressão linear simples entre o número acumulado de floretes abertos na haste floral e os dias após a emergência das plantas. O termo foi denominado "antocrono" e, em gladíolo, foi estimado como sendo o inverso do coeficiente angular da regressão linear, com a unidade dias por florete. O antocrono em gladíolo depende da cultivar e decresce com o aumento da temperatura do ar, durante o período de florescimento da espiga.

  3. Late Pleistocene songbirds of Liang Bua (Flores, Indonesia; the first fossil passerine fauna described from Wallacea

    Directory of Open Access Journals (Sweden)

    Hanneke J.M. Meijer

    2017-08-01

    Full Text Available Background Passerines (Aves: Passeriformes dominate modern terrestrial bird communities yet their fossil record is limited. Liang Bua is a large cave on the Indonesian island of Flores that preserves Late Pleistocene–Holocene deposits (∼190 ka to present day. Birds are the most diverse faunal group at Liang Bua and are present throughout the stratigraphic sequence. Methods We examined avian remains from the Late Pleistocene deposits of Sector XII, a 2 × 2 m area excavated to about 8.5 m depth. Although postcranial passerine remains are typically challenging to identify, we found several humeral characters particularly useful in discriminating between groups, and identified 89 skeletal elements of passerines. Results At least eight species from eight families are represented, including the Large-billed Crow (Corvus cf. macrorhynchos, the Australasian Bushlark (Mirafra javanica, a friarbird (Philemon sp., and the Pechora Pipit (Anthus cf. gustavi. Discussion These remains constitute the first sample of fossil passerines described in Wallacea. Two of the taxa no longer occur on Flores today; a large sturnid (cf. Acridotheres and a grassbird (Megalurus sp.. Palaeoecologically, the songbird assemblage suggests open grassland and tall forests, which is consistent with conditions inferred from the non-passerine fauna at the site. Corvus cf. macrorhynchos, found in the Homo floresiensis-bearing layers, was likely part of a scavenging guild that fed on carcasses of Stegodon florensis insularis alongside vultures (Trigonoceps sp., giant storks (Leptoptilos robustus, komodo dragons (Varanus komodoensis, and probably H. floresiensis as well.

  4. UMA “VIAGEM” AO MUNDO DOS ERP INSPIRADA EM WINOGRAD E FLORES

    Directory of Open Access Journals (Sweden)

    Gilson Ludmer

    2008-01-01

    Full Text Available Enterprise Resource Planning systems constitute a phenomenon of relevant dimension in the current business world and have been provoking radical changes in the market and in the administration ofinformation technology. This article analyses problems, limitations and new perspectives of the implementation of ERP (Enterprise Resource Planning in the organizations, through a parallel between selected ideas of Winograd and Flores’ classical work Understanding Computers and Cognition: a new foundation for design (1986, and the criticisms recently arisen to the implementation of these technologies. Criticisms and Winograd & Flores ideas are grouped in major themes. Central concerns are: the meaning of knowledge, as associated to ERP; the conditions to changes be made in a compatible way within its context; the problems of integration of ERP to cultural universe, processes and actions of the organizations. These concerns guided largely the choice of Winograd and Flores as reference for this essay. Almost 20 years after its publication, this work stays as influential exemple of how to recognize, in technological subjects, opportunities for the understanding of fundamental human and social processes

  5. El progresismo ecuatoriano en el siglo XIX. La reforma del presidente Antonio Flores (1888-1892

    Directory of Open Access Journals (Sweden)

    Mar\\u00EDa Cristina C\\u00E1rdenas Reyes

    2007-01-01

    Full Text Available La corriente política denominada progresismo en el siglo XIX ecuatoriano, una suerte de “tercera vía” distante de liberales y conservadores, se origina a mediados de siglo como proyecto republicano opuesto al autocratismo de Gabriel García Moreno. Luego del asesinato del mandatario, obtiene a fines de siglo un amplio reconocimiento en la esfera pública, movilizando un ideario reformador en que la categoría de progreso aparece como ideología, proceso y finalidad social. Alcanza su punto culminante con la presidencia de Antonio Flores en 1888, un católico liberal de formación europea apoyado desde Roma por el papa León XIII. Las reformas secularizantes de Flores originan su rechazo frontal por los depositarios del legado garciano, encabezados por la Iglesia ecuatoriana, y no llegan a concretarse en transformaciones institucionalizadas. La revolución liberal de 1895 en el país será en buena medida deudora de los avances impulsados por la corriente progresista

  6. The 1992 Flores Earthquake Revisited: From Earthquake Source to Tsunami Inundation

    Science.gov (United States)

    Latief, H.; Cummins, P. R.; Griffin, J.; Hossen, J.; Horspool, N.; Maher, N.; Fountain, L.; Hanung, R.; Rojali, A.; Kongko, W.

    2012-12-01

    The 1992 Flores earthquake (Mw=7.8) occurred on a back arc thrust near the island of Flores, Indonesia, causing widespread coastal uplift and subsidence, and generating a local tsunami with maximum runup height of over 25 meters that killed over 2,000 people. The event has been the subject of numerous publications on its various aspects, including the earthquake source mechanism determined from seismic data, and modelling of inundaiotn and tide gauge study data to study generation of the tsunami. To date, however, no studies have quantitatively assessed the constraints placed on the source mechanism by all the different types of data - seismic, geodetic and tsunami tide gauge waveforms and inundation. The opportunity to greatly improve the latter has presented itself recently through the availability of a high-resolution LiDAR data set for the topography along coastal strip near the earthquake. In this study we have undertaken a joint inversion of seismic and geodetic data available from this earthquake, and compared the results obtained to tsunami inundation and tide gauge data. We will present an assessment of what constraints the different data types place on the source mechanism, and how well these are compatible with the observed tsunami inundation results. Preliminary results suggest that the roughly 2 m inundation near Maumere is well explained, but the extreme tsunami run-up at Riang Kroko is not

  7. Two New Species of Simulium (Gomphostilbia) (Diptera: Simuliidae) From Flores, Indonesia.

    Science.gov (United States)

    Takaoka, Hiroyuki; Sofian-Azirun, Mohd; Chen, Chee Dhang; Lau, Koon Weng; Halim, Muhammad Rasul Abdullah; Low, Van Lun; Ya'cob, Zubaidah; Abdullah, Nurul Ashikin; Suana, I Wayan

    2017-05-01

    Two new species, Simulium (Gomphostilbia) sunapii and S. (G.) rangatense, are described based on adults, pupae, and mature larvae from Flores, in the eastern part of the Sunda Archipelago, Indonesia. Simulium (G.) sunapii sp. nov. is placed in the S. asakoae species-group, representing the easternmost geographical record for the group in this archipelago. It is characterized by a small number of male upper-eye large facets in eight or nine vertical columns and 12 horizontal rows. Simulium (G.) rangatense sp. nov. is placed in the S. ceylonicum species-group and is characterized by the pupal gill with six filaments. This new species, together with two related species of the S. ceylonicum species-group in Flores, suggests the species radiation of this species-group might have been accompanied by a reduction of the number of pupal gill filaments from eight to four through six. Taxonomic notes are provided to distinguish these two new species from related species. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com Version of Record, first published online December 14, 2016 with fixed content and layout in compliance with Art. 8.1.3.2 ICZN.

  8. Affine and Projective Geometry

    CERN Document Server

    Bennett, M K

    1995-01-01

    An important new perspective on AFFINE AND PROJECTIVE GEOMETRY. This innovative book treats math majors and math education students to a fresh look at affine and projective geometry from algebraic, synthetic, and lattice theoretic points of view. Affine and Projective Geometry comes complete with ninety illustrations, and numerous examples and exercises, covering material for two semesters of upper-level undergraduate mathematics. The first part of the book deals with the correlation between synthetic geometry and linear algebra. In the second part, geometry is used to introduce lattice theory

  9. Affinity in electrophoresis.

    Science.gov (United States)

    Heegaard, Niels H H

    2009-06-01

    The journal Electrophoresis has greatly influenced my approaches to biomolecular affinity studies. The methods that I have chosen as my main tools to study interacting biomolecules--native gel and later capillary zone electrophoresis--have been the topic of numerous articles in Electrophoresis. Below, the role of the journal in the development and dissemination of these techniques and applications reviewed. Many exhaustive reviews on affinity electrophoresis and affinity CE have been published in the last few years and are not in any way replaced by the present deliberations that are focused on papers published by the journal.

  10. The Hundred-Year Emotion War: Are Emotions Natural Kinds or Psychological Constructions? Comment on Lench, Flores, and Bench (2011)

    Science.gov (United States)

    Lindquist, Kristen A.; Siegel, Erika H.; Quigley, Karen S.; Barrett, Lisa Feldman

    2013-01-01

    For the last century, there has been a continuing debate about the nature of emotion. In the most recent offering in this scientific dialogue, Lench, Flores, and Bench (2011) reported a meta-analysis of emotion induction research and claimed support for the natural kind hypothesis that discrete emotions (e.g., happiness, sadness, anger, and…

  11. Review of Winograd and Flores'"Understanding Computers and Cognition": A Favorable Interpretation. ONR Technical Report #21.

    Science.gov (United States)

    Clancey, William J.

    Artificial Intelligence researchers and cognitive scientists commonly believe that thinking involves manipulating representations. Thinking involves search, inference, and making choices. This is how we model reasoning and what goes on in the brain is similar. Winograd and Flores present a radically different view, claiming that our knowledge is…

  12. Description of a new member of the Monarcha trivirgatа-group from Flores, Lesser Sunda Islands (Aves, Monarchinae)

    NARCIS (Netherlands)

    Mees, G.F.

    1973-01-01

    Amongst material from the island of Flores forwarded by the Rev. Fr. J. A. J. Verheijen SVD and the Rev. Fr. E. Schmutz SVD is a monarchine flycatcher which appears to represent an undescribed species. It may be known and diagnosed as follows. Monarcha sacerdotum species nova Type and unique specime

  13. Descripción del uso y manejo de plaguicidas en las empresas de flores afiliadas a Asocolflores

    National Research Council Canada - National Science Library

    Marcela E. Varona; Jorge E. Tolosa; Omayda Cárdenas; Carlos H. Torres; Darío Pardo; Gabriel Carrasquilla; Howard Frumkin

    2005-01-01

    ... pública debido al incremento de la demanda; esto ha ocasionado impacto en la salud de la población y en el ambiente. Objetivo. Describir los plaguicidas empleados y determinar su uso y manejo en las empresas de flores en la sabana...

  14. Affine dynamics with torsion

    Energy Technology Data Exchange (ETDEWEB)

    Gueltekin, Kemal [Izmir Institute of Technology, Department of Physics, Izmir (Turkey)

    2016-03-15

    In this study, we give a thorough analysis of a general affine gravity with torsion. After a brief exposition of the affine gravities considered by Eddington and Schroedinger, we construct and analyze different affine gravities based on the determinants of the Ricci tensor, the torsion tensor, the Riemann tensor, and their combinations. In each case we reduce equations of motion to their simplest forms and give a detailed analysis of their solutions. Our analyses lead to the construction of the affine connection in terms of the curvature and torsion tensors. Our solutions of the dynamical equations show that the curvature tensors at different points are correlated via non-local, exponential rescaling factors determined by the torsion tensor. (orig.)

  15. Melhoramento genético da mamona visando incremento de flores femininas

    Directory of Open Access Journals (Sweden)

    Fernanda Bertozzo

    2011-01-01

    Full Text Available O objetivo deste trabalho foi testar métodos de seleção visando ao aumento de flores femininas na população FCA-UNESP-PB de mamona (Ricinus communis L.. A seleção foi realizada no município de Botucatu (SP, na safrinha de 2007. Por meio de seleção massal, foram selecionadas plantas com racemo primário estritamente feminino. Destas plantas, as que tinham reversão sexual foram autofecundadas. As avaliações foram realizadas na safrinha de 2008 em Botucatu e São Manuel (SP, onde foram comparados os tratamentos: método de seleção massal; método de seleção massal com autofecundação e testemunha (racemos de plantas colhidos ao acaso, sem seleção. Foram avaliados: porcentagem de flores femininas do racemo primário (%, produtividade de grãos (kg ha-1 e teor de óleo das sementes (%. O delineamento experimental utilizado foi o de blocos casualizados com 30 repetições. Os dados foram submetidos à análise de variância individual para cada local e conjuntamente para os dois locais, pelo teste F a 1% de probabilidade. Mediante os resultados conclui- se que o método de seleção massal com autofecundação foi aquele que proporcionou maiores valores de porcentagem de flores femininas no racemo primário, com ganho fenotípico realizado de 18% em Botucatu e 29% em São Manuel (SP. Por meio dos métodos de seleção, notou-se comportamento diferencial em relação aos locais para a característica produtividade de grãos, e o método seleção massal com autofecundação proporcionou a menor produtividade. No teor de óleo não houve diferenças significativas entre os métodos e os locais avaliados.

  16. Affine and degenerate affine BMW algebras: Actions on tensor space

    CERN Document Server

    Daugherty, Zajj; Virk, Rahbar

    2012-01-01

    The affine and degenerate affine Birman-Murakami-Wenzl (BMW) algebras arise naturally in the context of Schur-Weyl duality for orthogonal and symplectic quantum groups and Lie algebras, respectively. Cyclotomic BMW algebras, affine and cyclotomic Hecke algebras, and their degenerate versions are quotients. In this paper we explain how the affine and degenerate affine BMW algebras are tantalizers (tensor power centralizer algebras) by defining actions of the affine braid group and the degenerate affine braid algebra on tensor space and showing that, in important cases, these actions induce actions of the affine and degenerate affine BMW algebras. We then exploit the connection to quantum groups and Lie algebras to determine universal parameters for the affine and degenerate affine BMW algebras. Finally, we show that the universal parameters are central elements--the higher Casimir elements for orthogonal and symplectic enveloping algebras and quantum groups.

  17. Entomofauna asociada a flores de berenjena y su papel en la producción de los frutos

    Directory of Open Access Journals (Sweden)

    Julianne MILLÉO

    2011-01-01

    Full Text Available El papel de los insectos polinizadores despierta interés, principalmente, en la reproducción de plantas tales como la berenjena. Este trabajo de recolección de la entomofauna asociada a las flores de Solanum melongena tuvo como objetivos identificar posibles agentes polinizadores locales y analizar el beneficio de los insectos antófilos a esta planta. Las observaciones y la colecta de los insectos visitantes de las flores fueron realizadas en febrero de 2008, entre las 7:00 y 17:15 horas, cada 45 minutos y en un área de 27 m2. El experimento para el análisis y la comparación entre autofecundación espontánea y polinización por medio de agentes bióticos fue realizado en el mismo sitio, de febrero a marzo de 2009. Fueron colectados 631 insectos que visitaban las flores de berenjena, se destacaron los coleópteros de los géneros Colaspis Fabricius, Astylus Laporte, Harmonia Mulsant, Epitrix Foudras y Diabrotica Chevrolat; y los himenópteros del género Bombus Latreille. El pico de visitación en Solanum melongena ocurrió entre las 9:00 y 11:00 horas y corresponde al 36% del muestreo. De las flores sometidas al test de autofecundación espontánea, el 39% formaron frutos, mientras que apenas el 11% de las flores emasculadas y expuestas al proceso de acción por medio de agentes bióticos fructificaron.

  18. Flore algale du Rhin canalisé : données récentes

    OpenAIRE

    Pierre, J.F.

    1996-01-01

    La communauté algale de trois stations du Rhin canalisé (Grand canal d'Alsace), au niveau du Centre de Production Nucléaire de Fessenheim, fait l'objet d'un suivi depuis 1977. Les présents résultats concernent la période 1988-1995. Ils mettent en évidence une stabilité de la flore algale au niveau de la diversité spécifique et de la répartition des espèces dominantes. L'inventaire diatomique s'enrichit d'une trentaine de taxons inédits pour ces stations. Ces données récentes confirment, au ni...

  19. Flore algale du Rhin canalisé : données récentes

    Directory of Open Access Journals (Sweden)

    PIERRE J. F.

    1996-04-01

    Full Text Available La communauté algale de trois stations du Rhin canalisé (Grand canal d'Alsace, au niveau du Centre de Production Nucléaire de Fessenheim, fait l'objet d'un suivi depuis 1977. Les présents résultats concernent la période 1988-1995. Ils mettent en évidence une stabilité de la flore algale au niveau de la diversité spécifique et de la répartition des espèces dominantes. L'inventaire diatomique s'enrichit d'une trentaine de taxons inédits pour ces stations. Ces données récentes confirment, au niveau de la communauté algale, l'absence d'impact visible du C R N . de Fessenheim.

  20. Diagnostico-Plan Regulador Cantón de Flores: Tomo 1

    OpenAIRE

    2013-01-01

    Este documento presenta datos, información y análisis propios de un diagnóstico que se elabora para diseñar un plan regulador cantonal de Flores, Costa Rica. También presenta los retos inmediatos y estratégicos que enfrentan los pobladores de la isla individual y colectivamente. Incluye múltiples partes: un diagnóstico biofísico que incluye mapas de uso del suelo. Una evaluación de los recursos biológicos, amenazas naturales, la orografía y topografía, la geología, capacidad de uso del suelo ...

  1. Gastronomía y cultura en la Ruta de Las Flores

    OpenAIRE

    Ventura Santos, Salomé Danilo

    2015-01-01

    Como resultado de una investigación socio territorial, este artículo contiene aspectos relevantes relacionados con la gastronomía y la cultura salvadoreña en particular de la Ruta de las Flores, ubicada en la zona occidental del país. Se realizó un recorrido y visitas de campo por los municipios que conforman esta ruta: Nahuizalco, Salcoatitán, Juayúa, Apaneca y Concepción de Ataco. Se conoció la riqueza gastronómica y cultural que posee esta región, donde por cierto aún se habla el idioma ná...

  2. Another Race between Islam and Christianity: The Case of Flores, Southeast Indonesia, 1900-1920

    Directory of Open Access Journals (Sweden)

    Karel Steenbrink

    2014-03-01

    Full Text Available Islam and Christianity arrived in the south-eastern islands of the Indonesian archipelago in two waves. The first wave started in about 1480 with the arrival of Arab and Indian (Gujerati traders in the spice islands of the Northern Moluccas: particularly in Ternate and Tidore. They arrived through the island of Flores, and probably very quickly moved across to the island of Timor as well, to engage in trade in sandalwood, horses and slaves. In south-east Indonesia, as in most regions of the archipelago, the arrival of Islam occurred somewhat earlier than the coming of the first Christians. At that time, the two main centers of trade in south-east Indonesia, which also became centers for the new religions, were the islands of Solor and Ende.Copyright (c 2014 by SDI. All right reserved.DOI: 10.15408/sdi.v9i1.674

  3. Estructura, ontogenia y vascularización de las flores e inflorescencias de Drimys granadensis (Winteraceae

    Directory of Open Access Journals (Sweden)

    Xavier Marquínez

    2014-08-01

    Full Text Available Drimys granadensis es una especie de amplia distribución en los bosques montanos de Sur y Centro América. En esta investigación se estudiaron, mediante microscopía óptica y electrónica de barrido, la estructura, ontogenia, filotaxis y vascularización de sus flores e inflorescencias, y fueron comparadas con las de Drimys winteri, especie distribuida en Chile y Argentina. Adicionalmente, se buscó evidencia para determinar la identidad bracteal o calicina de la caliptra de sus flores. Se confirmó la condición monotélica proliferante de la inflorescencia, descartando explicaciones alternativas de identidad de la flor terminal. Las uniflorescencias presentan un desarrollo acrópeto, hasta que el meristemo terminal se transforma en flor terminal, entonces esta flor se desarrolla rápidamente dando lugar a una uniflorescencia determinada. La vascularización es pseudosifonostélica para pedúnculos y pedicelos. Se encontró evidencia en la vascularización y estructura anatómica para considerar la caliptra como el producto de fusión de varias estructuras y, por tanto, de origen calicino. La caliptra presentó una filotaxis verticilada, pero los pétalos, estambres y carpelos presentaron una filotaxis espiralada; el cambio se explicó por el tiempo prolongado entre la iniciación de cáliz y corola. Las inflorescencias de D. granadensis y D. winteri son muy similares; siendo diferente el tiempo de inicio de la proliferación y la frecuente presencia de nomófilos en las inflorescencias de D. granadensis, en contraste con la presencia de brácteas y bracteolas reducidas en D. winteri.

  4. Diversidade de abelhas visitantes das flores de Citrus em pomares de laranjeira e tangerineira

    Directory of Open Access Journals (Sweden)

    Eduardo Tigre do Nascimento

    2011-03-01

    Full Text Available A presença de abelhas em culturas de valor comercial, no período de florescimento, é importante não apenas para garantir a polinização cruzada, quando indispensável, mas também para incrementar a produção de frutos e sementes. Nessa perspectiva, o presente trabalho teve a finalidade de identificar as abelhas visitantes das flores em pomar de laranjeira (Citrus sinensis e tangerineira (Citrus reticulata em Salinas - MG. O trabalho foi conduzido na fazenda experimental Santa Isabel, da Escola Agrotécnica Federal de Salinas - MG, em pomares de laranjeira com as variedades, pera, baía e baianinha, e de tangerineira, variedade poncã. As coletas das abelhas visitantes das culturas da laranjeira e tangerineira foram feitas nas floradas principais, entre os meses de agosto e outubro. Foram coletadas as abelhas que visitaram as flores nos horários entre 06 h e 18 h, totalizando 52 horas na laranjeira e 50 horas na tangerineira. No pomar de laranjeira, foram coletados 5.045 espécimes com riqueza de 12 espécies, e na tangerineira, 1.428 espécimes com 20 espécies. As espécies de abelhas de maior predominância e dominância em todos os horários amostrados foram Apis mellifera e Trigona spinipes na cultura da laranjeira e A. mellifera, T. spinipes e Tetragonisca angustula na cultura da tangerineira.

  5. Peñas arriba y flores en Otoño: el acceso al conocimiento

    Directory of Open Access Journals (Sweden)

    Barbara Sršen

    1991-12-01

    Full Text Available Después de unas diez páginas leídas de Peñas arriba de José María de Pereda se me ocurrió la idea de compararla con la novela Flores en otoño de Ivan Tavčar. Ni las obras nisus autores poseen relación alguna pero se pueden encontrar algunos puntos de contacto, que son interesantes, a pesar de que los planteamientos sean tan diferentes. Cuanto más profundizaba en ambas obras y buscaba sus cualidades y conexiones entre sí; así como los puntos de discordancia, mas me interesaba el asunto. Aparte la comparación de las dos novelas, surgían también algunas semejanzas en las vidas de ambos autores o en sus héroes literarios, pues en ambas hay datos autobiográficos indudables (sobre todo en Tavčar, con su abogado. Me pareció interesante el dato de que ambos autores escribieran sus novelas casi a la misma edad (Tavčar a los 65 años y Pereda a los 62 años de edad. A pesar de la diferencia de más de 20 años entre Peñas arriba y Flores en otoño y de Ia lejania en lo geográfico, que supone también distintos ambientes y diversas atmósferas sociales, no hay que olvidar el hecho (mencionado arriba de la edad de los autores al escribir las novelas respectivas.

  6. Caractérisation de flores microbiennes intestinale humaine et fromagère par méthode de métagénomique quantative

    OpenAIRE

    Almeida, Mathieu

    2013-01-01

    La flore microbienne est un ensemble de micro-organismes comme les bactéries, archées, eucaryotes inférieurs et virus, jouant un rôle important dans l’équilibre d’un écosystème. Cette flore reste encore mal définie car en 2012, seules ~30% des micro-organismes de la flore intestinale humaine étaient caractérisés, et moins de 50% des micro-organismes de la flore fromagère traditionnelle étaient caractérisés au niveau fonctionnel. Depuis 2006, les séquenceurs à ADN de seconde génération permett...

  7. Substrate affinity of photosensitizers derived from chlorophyll-a: the ABCG2 transporter affects the phototoxic response of side population stem cell-like cancer cells to photodynamic therapy.

    Science.gov (United States)

    Morgan, Janet; Jackson, Jennifer D; Zheng, Xiang; Pandey, Suresh K; Pandey, Ravindra K

    2010-10-04

    Photosensitizers (PS) synthesized with the aim of optimizing photodynamic therapy (PDT) of tumors do not always fulfill their potential when tested in vitro and in vivo in different tumor models. The ATP-dependent transporter ABCG2, a multidrug resistant pump expressed at variable levels in cancerous cells, can bind and efflux a wide range of structurally different classes of compounds including several PS used preclinically and clinically such as porphyrins and chlorins. ABCG2 may lower intracellular levels of substrate PS below the threshold for cell death in tumors treated by PDT, leaving resistant cells to repopulate the tumor. To determine some of the structural factors that affect substrate affinity of PS for ABCG2, we used an ABCG2-expressing cell line (HEK 293 482R) and its nonexpressing counterpart, and tyrosine kinase ABCG2 inhibitors in a simple flow cytometric assay to identify PS effluxed by the ABCG2 pump. We tested a series of conjugates of substrate PS with different groups attached at different positions on the tetrapyrrole macrocycle to examine whether a change in affinity for the pump occurred and whether such changes depended on the position or the structure/type of the attached group. PS without substitutions including pyropheophorbides and purpurinimides were generally substrates for ABCG2, but carbohydrate groups conjugated at positions 8, 12, 13, and 17 but not at position 3 abrogated ABCG2 affinity regardless of structure or linking moiety. At position 3, affinity was retained with the addition of iodobenzene, alkyl chains and monosaccharides, but not with disaccharides. This suggests that structural characteristics at position 3 may offer important contributions to requirements for binding to ABCG2. We examined several tumor cell lines for ABCG2 activity, and found that although some cell lines had negligible ABCG2 activity in bulk, they contained a small ABCG2-expressing side population (SP) thought to contain cells which are responsible

  8. Affine Sphere Relativity

    Science.gov (United States)

    Minguzzi, E.

    2016-11-01

    We investigate spacetimes whose light cones could be anisotropic. We prove the equivalence of the structures: (a) Lorentz-Finsler manifold for which the mean Cartan torsion vanishes, (b) Lorentz-Finsler manifold for which the indicatrix (observer space) at each point is a convex hyperbolic affine sphere centered on the zero section, and (c) pair given by a spacetime volume and a sharp convex cone distribution. The equivalence suggests to describe (affine sphere) spacetimes with this structure, so that no algebraic-metrical concept enters the definition. As a result, this work shows how the metric features of spacetime emerge from elementary concepts such as measure and order. Non-relativistic spacetimes are obtained replacing proper spheres with improper spheres, so the distinction does not call for group theoretical elements. In physical terms, in affine sphere spacetimes the light cone distribution and the spacetime measure determine the motion of massive and massless particles (hence the dispersion relation). Furthermore, it is shown that, more generally, for Lorentz-Finsler theories non-differentiable at the cone, the lightlike geodesics and the transport of the particle momentum over them are well defined, though the curve parametrization could be undefined. Causality theory is also well behaved. Several results for affine sphere spacetimes are presented. Some results in Finsler geometry, for instance in the characterization of Randers spaces, are also included.

  9. Affine stochastic mortality

    NARCIS (Netherlands)

    D.F. Schrager

    2006-01-01

    We propose a new model for stochastic mortality. The model is based on the literature on affine term structure models. It satisfies three important requirements for application in practice: analytical tractibility, clear interpretation of the factors and compatibility with financial option pricing m

  10. Genómica Funcional de Plantas: Estudio del Desarrollo de Flores y Frutos Genómica Funcional de Plantas: Estudio del Desarrollo de Flores y Frutos

    Directory of Open Access Journals (Sweden)

    Octavio Rubén Salazar Moya

    2012-02-01

    Full Text Available La última fase del desarrollo floral es la fertilización de los óvulos y la formación de los frutos,que son muy importantes tanto biológica como económicamente. Notoriamente, más del 80% de los alimentos que son consumidos por el ser humano proviene de flores y frutos.La obtención de conocimientos acerca de las bases moleculares del desarrollo de frutos en especies modelo es de gran interés científico, y un paso indispensable para poder facilitar investigaciones y de ser factible, aplicaciones en frutos de consumo humano. Especialmente en un país como México, con tal riqueza en la diversidad de frutos, este tipo de estudios es necesario y científicamente muy interesante, y tiene repercusiones económicas potenciales importantes. La meta del laboratorio es descubrir genes nuevos involucrados en el desarrollo de frutos, empleando los recursos que brindan plantas modelo como Arabidopsisthaliana. Se hace un enfoque especial en genes que afectan la identidad celular, morfología y que causan partenocarpia (frutos carentes de semillas, para más tarde estudiarlos enotras especies y hacer ensayos para conocer sus alcances en dichas especies.The last stages of fl oral development are ovule fertilization and fruit formation. Fruits are very important both biologically and economically. Notably, more than 80% of human food is obtained from flowers and fruits. Gathering basic knowledge about the molecular mechanisms of fruit development from model species is of great scientific interest, and is an essential step to facilitate research and, when feasible, applications in fruits consumed by humans. Especially in countries like Mexico, which has such a great diversity of fruits, this kind of research is both necessary and scientifically interesting, and has potentially important economic repercussions. The goal of the lab is to discover new genes that are involved inflower development, making use of the resources provided by model plants like

  11. Analyse de la flore, de la végétation ligneuse et des fonctions des ...

    African Journals Online (AJOL)

    zone péri-urbaine post-conflit (Ziguinchor, Sénégal). Maurice ... Mots clés : Vallées, végétation, flore, ménage, production agricole. Analysis of the flora, the ..... points d'eaux. La ... usées et d'un camp de la marine dans la vallée de Cobitène.

  12. A review of the evidence for genetic structure of cod ( Gadus morhua ) populations in the NW Atlantic and population affinities of larval cod off Newfoundland and the Gulf of St. Lawrence

    DEFF Research Database (Denmark)

    Ruzzante, D.E.; Taggart, C.T.; Cook, D.

    1999-01-01

    We review our recent studies on the genetic structure of Atlantic cod (Gadus morhua) populations in the NW Atlantic. Our conclusions are based on knowledge of polymorphism at microsatellite DNA loci combined with known aspects of cod biology and ecology and with known oceanographic features...... in the NW Atlantic. Three case studies illustrate genetic heterogeneity between cod populations at the meso- and large- scales of coastal embayments and offshore banks and at the small-scale of oceanographic features. Our results generally highlight the importance of combining genetic with physiological...... as barriers to gene-flow between and among neighboring and often contiguous cod populations in the NW Atlantic. We suggest that bathymetric and hydrodynamic/oceanographic structure represents a rational starting point for developing hypotheses aimed at assessing the genetic structure of high gene-flow marine...

  13. The subsurface three-dimensional modeling of volcano arc of Flores island based on gravity data analysis

    Science.gov (United States)

    Titi, Yopiter Lukas Alexander; Minarto, Eko

    2017-01-01

    The interpretation and three-dimensional modeling of the subsurface structure of the volcano arc of the Flores island based on the gravity data analysis have been done. This research is aimed for modeling subsurface structure utilized a secondary data of complete Bouguer anomaly gravity data obtained from Bureau Gravimetric International (BGI) using Grablox and Bloxer software. The modeling construction was performed by inversion technique applying the method of Singular Value Decomposition (SVD) and Occam inversion. The result indicates that Subsurface structure of the volcano area of the Flores island consists of sandstone, breccia and andesite have density value ranging from 2,42 g/cm3 to 2,62 g/cm3 and basaltic and lava have density values ranging from 2,65 g/cm3 to 3,24 g/cm3. The most dominating rocks in the study area are basaltic rocks have 2.73 g/cm3 point of average density. The existence of magma chamber in the volcanic arc of Flores island was estimated at a depth of 6 km.

  14. Affine and degenerate affine BMW algebras: The center

    CERN Document Server

    Daugherty, Zajj; Virk, Rahbar

    2011-01-01

    The degenerate affine and affine BMW algebras arise naturally in the context of Schur-Weyl duality for orthogonal and symplectic Lie algebras and quantum groups, respectively. Cyclotomic BMW algebras, affine Hecke algebras, cyclotomic Hecke algebras, and their degenerate versions are quotients. In this paper the theory is unified by treating the orthogonal and symplectic cases simultaneously; we make an exact parallel between the degenerate affine and affine cases via a new algebra which takes the role of the affine braid group for the degenerate setting. A main result of this paper is an identification of the centers of the affine and degenerate affine BMW algebras in terms of rings of symmetric functions which satisfy a "cancellation property" or "wheel condition" (in the degenerate case, a reformulation of a result of Nazarov). Miraculously, these same rings also arise in Schubert calculus, as the cohomology and K-theory of isotropic Grassmanians and symplectic loop Grassmanians. We also establish new inte...

  15. Hierarchical Affinity Propagation

    CERN Document Server

    Givoni, Inmar; Frey, Brendan J

    2012-01-01

    Affinity propagation is an exemplar-based clustering algorithm that finds a set of data-points that best exemplify the data, and associates each datapoint with one exemplar. We extend affinity propagation in a principled way to solve the hierarchical clustering problem, which arises in a variety of domains including biology, sensor networks and decision making in operational research. We derive an inference algorithm that operates by propagating information up and down the hierarchy, and is efficient despite the high-order potentials required for the graphical model formulation. We demonstrate that our method outperforms greedy techniques that cluster one layer at a time. We show that on an artificial dataset designed to mimic the HIV-strain mutation dynamics, our method outperforms related methods. For real HIV sequences, where the ground truth is not available, we show our method achieves better results, in terms of the underlying objective function, and show the results correspond meaningfully to geographi...

  16. Purely affine Gravity

    CERN Document Server

    Skirzewski, Aureliano

    2014-01-01

    We develop a topological theory of gravity with torsion where metric has a dynamical rather than a kinematical origin. This approach towards gravity resembles pre-geometrical approaches in which a fundamental metric does not exist, but the affine connection gives place to a local inertial structure. Such feature reminds us of Mach's principle, that assumes the inertial forces should have dynamical origin. Additionally, a Newtonian gravitational force is obtained in the non-relativistic limit of the theory.

  17. Flores, Fernández y Oliva: tres azulejeros para las obras reales de Felipe II

    Directory of Open Access Journals (Sweden)

    Pleguezuelo, Alfonso

    2002-06-01

    Full Text Available Que las obras de arquitectura promocionadas por Felipe II eran acabadas frecuentemente con revestimientos de azulejos es una idea conocida desde hace tiempo. El ejemplo más frecuentemente aducido es el de los aposentos del mismo rey en el Monasterio de San Lorenzo de El Escorial aunque podrían ser citados muchos más casos conservados y otros conocidos a través de la documentación. Este rasgo de la arquitectura filipina y el personal interés del rey por el asunto debió ser un importante acicate para el desarrollo de la azulejería española en la segunda mitad del siglo XVI. Tres artistas han sido citados desde hace años como autores de los azulejos para Felipe II. Por un lado, el flamenco Juan Flores, del que tan sólo se tenían unas pocas noticias literarias sobre su vida y su obra y que recientemente he tenido la oportunidad de revisar a luz de nuevos documentos y obras.…

  18. Characteristic of geothermal fluid at East Manggarai, Flores, East Nusa Tenggara

    Science.gov (United States)

    Iqbal, Mochamad; Herdianita, Niniek Rina; Risdianto, Dikdik

    2016-09-01

    The research area is located in East Manggarai and its surrounding area, Flores. In the study area there are two geothermal systems, i.e. Mapos geothermal system which is associated with Anak Ranakah volcano and Rana Masak geothermal systems which is associated with Watuweri volcano. The difference within these systems is shown by the relative content of conservative elements of Cl, Li and B. Geothermal surface manifestations in Mapos include 4 hot springs having temperatures of 34,3-51,4°C and bicarbonate and sulphate-bicarbonate waters; the discharge area in Rana Masak consist of 3 hot springs with temperatures of 38-46,6°C and chloride and chloride-bicarbonate water. Stable isotopes δ18O and δD analyses showed that the geothermal fluid derived from meteoric water. The Mapos geothermal system is a high temperature system having reservoir temperature of 250-270°C with natural heat loss of 230 kW. The Rana Masak geothermal system is a low temperature system having reservoir temperature of 120-140°C with natural heat loss of 120 kW.

  19. Estado gel do corpo ficcional em 'Rosa canina' e "Flores", de Mario Bellatin

    Directory of Open Access Journals (Sweden)

    Isabel Jasinski

    2015-06-01

    Full Text Available Mario Bellatin cria um espaço de sentido peculiar na ficção, relacionado à expressão visual e performática da linguagem. Assim, escrever se apresenta como linguagem do corpo em seu projeto literário, um território de significância constantemente desterritorializado por sensações conectadas ao jogo narrativo, com imagens e símbolos, nas ações literárias. Um sentido de destruição criativa constitui o paradoxo expresso pela ficção como corpo e pelo corpo como ficção, naquilo que consideramos a “escrita nômade” de Bellatin, por meio da anormalidade dos personagens, da sua sexualidade e sua religiosidade, como se pode comprovar em Flores (2000, especialmente em “Rosa canina”, publicado online pela Cosac Naify em 2009. A posição adotada pelo protagonista nessa obra parece indicar um “regime de significação” específico, como entende Josefina Ludmer, segundo o qual arte e realidade, ficção e biografia apagam suas fronteiras num “estado gel do intercâmbio”.

  20. ASPECTOS DA PRODUÇÃO E CONSUMO DE FLORES E PLANTAS ORNAMENTAIS NO BRASIL

    Directory of Open Access Journals (Sweden)

    AUGUSTO AKI

    2002-08-01

    Full Text Available O presente artigo tem por objetivo uma análise sobre a constituição do mercado de flores e plantas ornamentais no Brasil, aspectos de marketing envolvidos nessa evolução e a sistematização de informações sobre produção e consumo. Inicialmente, é apresentada a evolução desse mercado, elaborada a partir de estudos de técnicos e consultores da área. Segue-se a apresentação de dados e informações de estudos e pesquisas elaborados sobre a evolução da produção. A maioria das informações apresentada consta da pesquisa de campo “Prospecção de Produtos e Mercados: Cadeia Produtiva Nacional”, levada a efeito pelo Instituto Brasileiro de Floricultura (IBRAFLOR com o apoio da Agência de Promoção de Exportações (APEX, e publicada no início de 2003. Com base na estruturação do mercado, produção e consumo, são sugeridas ações visando à maior eficiência da cadeia.

  1. Fractal Analysis on the Correlation of Coastal Line Geometry and Tsunami Impact in Maumere, Flores, Indonesia

    Directory of Open Access Journals (Sweden)

    SARI BAHAGIARTI KUSUMAYUDHA

    2011-12-01

    Full Text Available Almost all of the Indonesian territories are high potential of geologic disaster, such as earthquake, tsunami, volcanic eruptions and landslides, because the country belongs to tectonically active areas of the world. There are three big lithosperic plates interacting one with one another and influencing the tectonic setting of Indonesia. The plates are Indo-Australia plate, Eurasia plate and Pacific plate. Indo-Australia plate moves relatively northward by about 9 cm/year, Eurasia plate creeps south eastward with approximately 7 cm/year speed, and Pacific plate moves to the west with around 11 cm/year velocity. In the meeting line of the plates, about 300 km to the south of Indonesian islands, there is the subduction zone that become places, where earthquake focuses are generated. Earthquakes from submarine source with more than 6.5 magnitude have the potential to generate tsunami. Areas situated along the south coast of Indonesia islands are vulnerable to tsunami, because directly facing the boundary lines between Eurasia plate and Indo-Australia plate. This study verified that there is positive correlation between coastal line geometry and the tsunami impact, based on fractal analysis. The case study is Maumere, Flores island, East Nusa Tenggara, Indonesia. Result of the study is expected to be used for predicting the tsunami impact intensiveness at other areas.

  2. Identifikasi longsoran bawah laut berdasarkan penafsiran seismik pantul di perairan Flores

    Directory of Open Access Journals (Sweden)

    Kris Budiono

    2014-06-01

    Full Text Available http://dx.doi.org/10.17014/ijog.vol4no1.20092Submarine sliding frequently cause tsunami or a high velocity big wave around the submarine slid- ing area which enable to reach a long distance. This sliding is not always as a causal factor for hazard and even associate with storm and earthquake. Some of them occur in a narrow area and it’s just formed due to gravitational movement. Different with mechanism of landslide, which is commonly due to water saturated soil, the submarine sliding is a more complex event. The submarine sliding is an important natural process which causes a big volume of sediment mass moves from a shallow area to a much deeper area of seafloor. There are many types and causal factors of seafloor instability, but the sliding terminology is predominantly used for the phenomena. A variety of seafloor materials, environments and sediment masses are some extreme influential factors in creat- ing the types of submarine sliding. The reflector of seismics is usefull to interpret the indications of the occurrence of geological structure and sub-marine slumping In case of the Flores Sea, earthquake is a major causal factor for creating submarine sliding. The bigger magnitude of earthquake, the greater the dimension of submarine sliding. Eventually, it may affect to the more possible occurrence of a potential hazardous tsunami.  

  3. Identifikasi longsoran bawah laut berdasarkan penafsiran seismik pantul di perairan Flores

    Directory of Open Access Journals (Sweden)

    Kris Budiono

    2014-06-01

    Full Text Available http://dx.doi.org/10.17014/ijog.vol4no1.20092Submarine sliding frequently cause tsunami or a high velocity big wave around the submarine slid- ing area which enable to reach a long distance. This sliding is not always as a causal factor for hazard and even associate with storm and earthquake. Some of them occur in a narrow area and it’s just formed due to gravitational movement. Different with mechanism of landslide, which is commonly due to water saturated soil, the submarine sliding is a more complex event. The submarine sliding is an important natural process which causes a big volume of sediment mass moves from a shallow area to a much deeper area of seafloor. There are many types and causal factors of seafloor instability, but the sliding terminology is predominantly used for the phenomena. A variety of seafloor materials, environments and sediment masses are some extreme influential factors in creat- ing the types of submarine sliding. The reflector of seismics is usefull to interpret the indications of the occurrence of geological structure and sub-marine slumping In case of the Flores Sea, earthquake is a major causal factor for creating submarine sliding. The bigger magnitude of earthquake, the greater the dimension of submarine sliding. Eventually, it may affect to the more possible occurrence of a potential hazardous tsunami.  

  4. On the Affine Isoperimetric Inequalities

    Indian Academy of Sciences (India)

    Wuyang Yu; Gangsong Leng

    2011-11-01

    We obtain an isoperimetric inequality which estimate the affine invariant -surface area measure on convex bodies. We also establish the reverse version of -Petty projection inequality and an affine isoperimetric inequality of $_{-p}K$.

  5. Affine morphisms at zero level

    CERN Document Server

    Das, Paramita; Gupta, Ved Prakash

    2010-01-01

    Given a finite index subfactor, we show that the {\\em affine morphisms at zero level} in the affine category over the planar algebra associated to the subfactor is isomorphic to the fusion algebra of the subfactor as a *-algebra.

  6. Affine and quasi-affine frames for rational dilations

    DEFF Research Database (Denmark)

    Bownik, Marcin; Lemvig, Jakob

    2011-01-01

    , the corresponding family of quasi-affine systems are frames with uniform frame bounds. We also prove a similar equivalence result between pairs of dual affine frames and dual quasi-affine frames. Finally, we uncover some fundamental differences between the integer and rational settings by exhibiting an example......In this paper we extend the investigation of quasi-affine systems, which were originally introduced by Ron and Shen [J. Funct. Anal. 148 (1997), 408-447] for integer, expansive dilations, to the class of rational, expansive dilations. We show that an affine system is a frame if, and only if...

  7. Affine Patches on Positroid Varieties and Affine Pipe Dreams (Thesis)

    CERN Document Server

    Snider, Michelle

    2010-01-01

    The objects of interest in this thesis are positroid varieties in the Grassmannian, which are indexed by juggling patterns. In particular, we study affine patches on these positroid varieties. Our main result corresponds these affine patches to Kazhdan-Lusztig varieties in the affine Grassmannian. We develop a new term order and study how these spaces are related to subword complexes and Stanley-Reisner ideals. We define an extension of pipe dreams to the affine case and conclude by showing how our affine pipe dreams are generalizations of Cauchon and Le diagrams.

  8. Follajes comercializados en dos mercados de flores del Altiplano Central Mexicano

    Directory of Open Access Journals (Sweden)

    Graciela Noemi Grenón-Cascales

    2015-07-01

    Full Text Available Los tradicionales mercados de flores Xochiquetzal del municipio de Tenancingo, Estado de México y Jamaica en el Distrito Federal, son importantes en la comercialización de especies de follajes, de los cuales se desconoce su filiación taxonómica, por lo que resulta relevante realizar su inventario. Para ello, se visitaron ambos mercados para la adquisición de las especies, y su posterior herborización e identifi cación taxonómica en el herbario de la facultad de Ciencias Agrícolas de la Universidad Autónoma del Estado de México. Adicionalmente se obtuvo información complementaria de cada una de ellas a través de encuestas aplicadas. Con los datos obtenidos se realizó el inventario y el catálogo de follajes de ambos mercados.Los resultados obtenidos muestran que el número de especies comercializadas en los dos mercados es de 87 especies, las cuales pertenecen a 57 géneros y 38 familias. El mayor número de especies de follajes se comercializan en forma de manojo (43% y el menor número corresponde a racimos de frutos (3%; el mayor número de especies de follajes se comercializan en el mercado de Jamaica (71% y sólo el 13% en el mercado de Tenancingo. La familia Araceae muestra un mayor número de especies de follajes (10%. Estos datos se deben a que sus especies tienen inflorescencias muy llamativas y que tienen una larga vida en florero. La información recopilada en el catálogo servirá de difusión y apoyo para establecer estrategias de conservación y uso sustentable de las especies comercializadas en los mercados, objeto de estudio.

  9. RELACIONES GENOMICAS ENTRE CUATRO ESPECIES DIPLOIDES DE TURNERA CON FLORES AMARILLAS (SERIE CANALIGERAE

    Directory of Open Access Journals (Sweden)

    Aveliano Mercedes Fernández

    2010-11-01

    Full Text Available

    Los rasgos morfológicos y citogenéticos de los híbridos artificiales entre cuatro especies diploides (2n = 10: T.concinna, T.Krapovickasii, T.scabra y T.subulata han sido estudiados. Los híbridos fueron intermedios en varios caracteres, como el color de las flores, la longitud, la anchura y forma de las semillas, en algunos rasgos se parecían a uno o al otro padre.
    Todos los híbridos interespecíficos mostraron un alto porcentaje de PMC con cinco bivalentes. La meiosis de T.subulata x T.scabra fue regular (5 II. En los otros híbridos fue grabada una baja frecuencia de trivalentes o cuadrivalentes; estos trivalentes y cuadrivalentes son evidencia de translocaciones recíprocas. Puentes y fragmentos en anafase I y II muestran la presencia de inversiones paracéntricas.
    Los análisis morfológicos y citogenéticos de los híbridos indican una estrecha relación entre T.scabra y T.subulata y entre T.concinna y T.Krapovickasii respectivamente. Esta última especie tiene un par de cromosomas con satélites grandes. T.scabra y T.concinna están más alejadas.
    El estudio citogenético de todos los híbridos entre estas especies confirmaría que son taxones independientes. Ellos tienen el mismo genoma básico, que designamos Asu Asu de T. subulata, Asc Asc para T.scabra, Ak Ak para T. Krapovickasii y Ac Ac para T.concinna.

  10. Esencia Floral a partir de Residuos Orgánicos (pétalos de flores

    Directory of Open Access Journals (Sweden)

    Amelia Vidales Olivo

    2003-01-01

    Full Text Available La perfumería es el arte de producir aromas mediante la combinación de sustancias odoríficas, esto se puede llevar a cabo cuando se recicla por separado los deshechos de pétalos frescos y secos, aplicando el proceso de extracción, para obtener los aromas (fragancias, agradables y característicos de las flores. Proceso aplicado a los diferentes pétalos recolectados, como materia prima; se conoció el rendimiento del producto obtenido. Las técnicas o métodos aplicados son a nivel laboratorio realizados en el área de química cualitativa basadas en microtécnicas de extracción de destilación, maceración en grasa y absorción en alcohol; efectuando el correspondiente estudio financiero para conocer los costos. Todo esto fue verificado bajo los más estrictos controles de calidad que establece la norma oficial mexicana que rigen a la perfumería. Las esencias concentradas, obtenidas fueron los volúmenes de (4, 8, 250 y 300 mililitros. Mismos que se probo su efectividad con los estudiantes seleccionados del instituto tecnológico; aplicándose de inmediato una encuesta, para saber si se tenían reacciones alérgicas con el producto y si el aroma fue del agrado, encontrando muy buena aceptación y comentarios positivos como la duración prolongada del aroma, con calificativos como: ésta muestra es olor dulce, fresca, agradable, con olor a rosas; se adiciona otro calificativo más de parte del equipo investigador, de ser muy económico.

  11. Affinity Purification of Insulin by Peptide-Ligand Affinity Chromatography

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The affinity heptapeptide (HWWWPAS) for insulin, selected from phage display library,was coupled to EAH Sepharose 4B gel and packed to a 1-mL column. The column was used for the affinity purification of insulin from protein mixture and commercial insulin preparation. It was observed that the minor impurity in the commercial insulin was removed by the affinity chromatography. Nearly 40 mg of insulin could be purified with the 1-mL affinity column. The results revealed the high specificity and capacity of the affinity column for insulin purification. Moreover, based on the analysis of the amino acids in the peptide sequence, shorter peptides were designed and synthesized for insulin chromatography. As a result, HWWPS was found to be a good alternative to HWWWPAS, while the other two peptides with three or four amino acids showed weak affinity for insulin. The results indicated that the peptide sequence of HWWWPAS was quite conservative for specific binding of insulin.

  12. Influence of storage temperature on Epidendrum ibaguense flowers = Influência da temperatura de armazenamento em flores de Epidendrum ibaguense.

    Directory of Open Access Journals (Sweden)

    Ana Maria Mapeli

    2011-01-01

    Full Text Available The present work was carried out to evaluate the influence oftemperature and wet-versus-dry storage on longevity, respiration and ethylene production during storage of E. ibaguense flowers. The inflorescences were harvested and stored at 5, 10, 15, 20, 25, 30, 35, and 40oC, in water or dry, until complete senescence. Respiration increased when inflorescences were treated with wet or dry storage. The Q10 factor for this flower, at temperatures ranging from 5 to 40°C, was similar to most fresh horticultural products, varying between 1.2 and 3.31 depending on storage temperature. Production of ethylene by the inflorescence was maximal at 20ºC for flowers maintained in water, and at 35°C for those flowers kept dry, followedby a sharp drop in both treatments. A maximal shelf life for cut flowers was obtained when the inflorescences were stored wet at 10°C. Symptoms of chilling were observed in flowers stored in water after six to seven days at 5°C, showing petal wilting and necrosis of the labellum. At 40°C, flowers stored dry showed severe petal wilting anddarkening of bud petals less than one day after harvest.O presente trabalho avaliou a influência da temperatura e armazenamento úmido e seco sobre a longevidade, respiração e produção de etileno de flores de Epidendrum ibaguense. As hastes foram colhidas, colocadas em vaso e armazenadas em temperatura de 5, 10, 15, 20, 25, 30, 35 e 40oC, em água ou a seco, até completa senescência das flores. A respiração aumentou quando as inflorescências foram tratadas com armazenamento úmido ou seco. O fator Q10 para estas flores, na faixa de temperatura de 5 a 40ºC, foi similar a da maioria dos produtos hortícolas, variando de 1,2 a 3,3, dependendo da temperatura de armazenamento. A produção de etileno foi máxima a 20ºC, para as flores mantidas em água, e a 35ºC para aquelasmantidas a seco, e a partir destas temperaturas houve redução em ambos os tratamentos. A longevidade foi m

  13. Jacobi Structures on Affine Bundles

    Institute of Scientific and Technical Information of China (English)

    J. GRABOWSKI; D. IGLESIAS; J. C. MARRERO; E. PADR(O)N; P. URBA(N)SKI

    2007-01-01

    We study affine Jacobi structures (brackets) on an affine bundle π: A→M, i.e. Jacobi brackets that close on affine functions. We prove that if the rank of A is non-zero, there is a one-to- one correspondence between affine Jacobi structures on A and Lie algebroid structures on the vector bundle A+=∪p∈M Aff(Ap, R) of affine functionals. In the case rank A = 0, it is shown that there is a one-to-one correspondence between affins Jacobi structures on A and local Lie algebras on A+. Some examples and applications, also for the linear case, are discussed. For a special type of affine Jacobi structures which are canonically exhibited (strongly-affine or affine-homogeneous Jacobi structures) over a real vector space of finite dimension, we describe the leaves of its characteristic foliation as the orbits of an affine representation. These afline Jacobi structures can be viewed as an analog of the Kostant-Arnold-LiouviUe linear Poisson structure on the dual space of a real finite-dimensional Lie algebra.

  14. Flores Celestes (1807: O livro secreto de José da Silva Lisboa, o visconde de Cairú

    Directory of Open Access Journals (Sweden)

    Iglesias Magalhães, Pablo Antonio

    2013-12-01

    Full Text Available The present article investigates the origins of a mysterious little book intitled Flores celestes colhidas entre os espinhos da sagrada coroa da augusta, veneravel e soberana cabeça do divino e immortal rei dos seculos Jesus Christo, of authorship of the enigmatic bahiense poet Jose Cortez Sol Posto, also known as Cigano da Bahia. The inquiry demonstrates that, under the layer of merciful poetries, the confessions of one of the most representative personages of the History of Brazil in century XIX are hidden.En este artículo se investiga el origen de un misterioso y pequeño libro titulado Flores celestes colhidas entre os espinhos da sagrada coroa da augusta, veneravel e soberana cabeça do divino e immortal rei dos seculos Jesus Christo, escrito por el enigmático poeta bahiense José Cortez Sol Posto, también conocido como Cigano da Bahia. La investigación muestra que, bajo el pretexto de la poesía piadosa, se esconden las confesiones de uno de los personajes más importantes de la historia de Brasil en el siglo XIX. [pt] O presente artigo investiga as origens de um livrinho misterioso intitulado Flores celestes colhidas entre os espinhos da sagrada coroa da augusta, veneravel e soberana cabeça do divino e immortal rei dos seculos Jesus Christo, de autoria do enigmático poeta bahiense José Cortez Sol Posto, também conhecido como Cigano da Bahia. A investigação demonstra que, sob a capa de poesias piedosas, escondem-se as confissões de um dos mais representativos personagens da História do Brasil no século XIX.

  15. Kernel Affine Projection Algorithms

    Directory of Open Access Journals (Sweden)

    José C. Príncipe

    2008-05-01

    Full Text Available The combination of the famed kernel trick and affine projection algorithms (APAs yields powerful nonlinear extensions, named collectively here, KAPA. This paper is a follow-up study of the recently introduced kernel least-mean-square algorithm (KLMS. KAPA inherits the simplicity and online nature of KLMS while reducing its gradient noise, boosting performance. More interestingly, it provides a unifying model for several neural network techniques, including kernel least-mean-square algorithms, kernel adaline, sliding-window kernel recursive-least squares (KRLS, and regularization networks. Therefore, many insights can be gained into the basic relations among them and the tradeoff between computation complexity and performance. Several simulations illustrate its wide applicability.

  16. Kernel Affine Projection Algorithms

    Science.gov (United States)

    Liu, Weifeng; Príncipe, José C.

    2008-12-01

    The combination of the famed kernel trick and affine projection algorithms (APAs) yields powerful nonlinear extensions, named collectively here, KAPA. This paper is a follow-up study of the recently introduced kernel least-mean-square algorithm (KLMS). KAPA inherits the simplicity and online nature of KLMS while reducing its gradient noise, boosting performance. More interestingly, it provides a unifying model for several neural network techniques, including kernel least-mean-square algorithms, kernel adaline, sliding-window kernel recursive-least squares (KRLS), and regularization networks. Therefore, many insights can be gained into the basic relations among them and the tradeoff between computation complexity and performance. Several simulations illustrate its wide applicability.

  17. Flores comestíveis: múltiplas utilizações do mais belo da natureza

    OpenAIRE

    2014-01-01

    As flores comestíveis têm vindo a tornar-se cada vez mais populares, o que se torna claramente evidente pelo aumento de livros de receitas, artigos de revistas e sites sobre o tema, para além do crescimento da investigação científica relacionada com o seu potencial nutricional. O foco principal é a alta gastronomia, atraindo a atenção de gourmets e chefs. Projecto bilateral FCT – CNPq, Portugal/Brazil 2014-2016

  18. Flores Celestes: o livro secreto de José da Silva Lisboa, o visconde de Cairú?

    Directory of Open Access Journals (Sweden)

    Pablo Antonio Iglesias Magalhães

    2012-06-01

    Full Text Available O presente artigo investiga as origens de um livrinho misterioso intitulado Flores celestes colhidas entre os espinhos da sagrada coroa da augusta, veneravel e soberana cabeça do divino e immortal rei dos seculos Jesus Christo, de autoria do enigmático poeta bahiense José Cortez Sol Posto, também conhecido como Cigano da Bahia. A investigação demonstra que, sob a capa de poesias piedosas, escondem-se as confissões de um dos mais representativos personagens da História do Brasil no século XIX.

  19. Adjoint affine fusion and tadpoles

    Science.gov (United States)

    Urichuk, Andrew; Walton, Mark A.

    2016-06-01

    We study affine fusion with the adjoint representation. For simple Lie algebras, elementary and universal formulas determine the decomposition of a tensor product of an integrable highest-weight representation with the adjoint representation. Using the (refined) affine depth rule, we prove that equally striking results apply to adjoint affine fusion. For diagonal fusion, a coefficient equals the number of nonzero Dynkin labels of the relevant affine highest weight, minus 1. A nice lattice-polytope interpretation follows and allows the straightforward calculation of the genus-1 1-point adjoint Verlinde dimension, the adjoint affine fusion tadpole. Explicit formulas, (piecewise) polynomial in the level, are written for the adjoint tadpoles of all classical Lie algebras. We show that off-diagonal adjoint affine fusion is obtained from the corresponding tensor product by simply dropping non-dominant representations.

  20. Adjoint affine fusion and tadpoles

    CERN Document Server

    Urichuk, Andrew

    2016-01-01

    We study affine fusion with the adjoint representation. For simple Lie algebras, elementary and universal formulas determine the decomposition of a tensor product of an integrable highest-weight representation with the adjoint representation. Using the (refined) affine depth rule, we prove that equally striking results apply to adjoint affine fusion. For diagonal fusion, a coefficient equals the number of nonzero Dynkin labels of the relevant affine highest weight, minus 1. A nice lattice-polytope interpretation follows, and allows the straightforward calculation of the genus-1 1-point adjoint Verlinde dimension, the adjoint affine fusion tadpole. Explicit formulas, (piecewise) polynomial in the level, are written for the adjoint tadpoles of all classical Lie algebras. We show that off-diagonal adjoint affine fusion is obtained from the corresponding tensor product by simply dropping non-dominant representations.

  1. Adjoint affine fusion and tadpoles

    Energy Technology Data Exchange (ETDEWEB)

    Urichuk, Andrew, E-mail: andrew.urichuk@uleth.ca [Physics and Astronomy Department, University of Lethbridge, Lethbridge, Alberta T1K 3M4 (Canada); Walton, Mark A., E-mail: walton@uleth.ca [Physics and Astronomy Department, University of Lethbridge, Lethbridge, Alberta T1K 3M4 (Canada); International School for Advanced Studies (SISSA), via Bonomea 265, 34136 Trieste (Italy)

    2016-06-15

    We study affine fusion with the adjoint representation. For simple Lie algebras, elementary and universal formulas determine the decomposition of a tensor product of an integrable highest-weight representation with the adjoint representation. Using the (refined) affine depth rule, we prove that equally striking results apply to adjoint affine fusion. For diagonal fusion, a coefficient equals the number of nonzero Dynkin labels of the relevant affine highest weight, minus 1. A nice lattice-polytope interpretation follows and allows the straightforward calculation of the genus-1 1-point adjoint Verlinde dimension, the adjoint affine fusion tadpole. Explicit formulas, (piecewise) polynomial in the level, are written for the adjoint tadpoles of all classical Lie algebras. We show that off-diagonal adjoint affine fusion is obtained from the corresponding tensor product by simply dropping non-dominant representations.

  2. Sobre el debate Habermas/Flores D’arcais en torno al papel de la religión en la esfera pública

    Directory of Open Access Journals (Sweden)

    José María Panea

    2015-01-01

    Full Text Available El filósofo P. Flores D’Arcais ha escrito, como si fuera Marx contra Feuerbach, once tesis contra Habermas. Sin embargo, el propio Habermas ha mostrado su perplejidad por tales críticas. En el presente trabajo analizamos ambas posiciones filosóficas. Tratamos de hacer justicia al pensamiento de Habermas en materia de religión y esfera pública, a la vez que señalamos las inconsistencias de la interpretación y de las propuestas de P. Flores en el contexto del patriotrismo constitucional.

  3. Beija-flores (Aves, Trochilidae) e seus recursos florais em uma área urbana do Sul do Brasil Hummingbirds (Aves, Trochilidae) and their flowers in an urban area of southern Brazil

    OpenAIRE

    Luciana Baza Mendonça; Luiz dos Anjos

    2005-01-01

    A assembléia de flores visitadas por beija-flores e a partilha de recursos entre estas aves foram estudadas em uma área urbana do sul do Brasil. Vinte e duas espécies de plantas, em sua maioria exóticas e/ou não-ornitófilas, receberam visitas dos beija-flores. As espécies de beija-flores registradas apresentaram diferentes combinações de características morfológicas (massa, comprimento do bico, comprimento da asa e relação bico/asa), que refletiram no conjunto de flores exploradas e no papel ...

  4. The Flores speleothem carbon isotope record: vegetation, volcanism and the demise of Homo floresiensis

    Science.gov (United States)

    Scroxton, N.; Gagan, M. K.; Ayliffe, L. K.; Hantoro, W. S.; Hellstrom, J. C.; Cheng, H.; Edwards, R. L.; Zhao, J. X.; Suwargadi, B. W.; Scott-Gagan, H.; Cowley, J. A.; Rifai, H.

    2015-12-01

    The last surviving non-human member of the Homo genus: Homo floresiensis, disappeared from the stratigraphic record in Liang Bua cave, Flores, Indonesia, between 17 and 10 kyr BP (Roberts et al. 2009, J. Hum. Evol.). The cause of the disappearance (e.g. climate change, volcanic catastrophe or human competition) has not been established. Here, we present a new 92,000-year long speleothem δ13C record for Liang Luar cave, 800m South of Liang Bua. Our record acts as a proxy for local environmental and vegetation health throughout H. floresiensis' occupation of the area. The Liang Luar speleothem δ13C record is primarily a record of vegetation productivity and soil respiration rates, highlighting local ecological responses to changing regional and global climate forcings such as temperature, atmospheric pCO2 and precipitation amount. Changes in speleothem δ13C can largely be considered an environmental response to climate change. Events that caused significant harm to the local environment and H. floresiensis are likely to be outside the natural range of variability: being quick enough or extreme enough that adaptation to new conditions is not possible. We identify disturbances to the vegetation system using two indicators in the speleothem record. 1) Abrupt positive δ13C excursions which indicate periods of reduced vegetative activity. 2) A loss of correlation between the δ13C and δ18O records, indicating that precipitation is no longer a dominant control on vegetation productivity. The largest (8‰) and longest (7 kyr) abrupt positive excursion, the 68 kyr event, sees positive speleothem δ13C values, due to increased bedrock contribution and/or C4 vegetation at this time. Crucially a H. floresiensis occupation interval dates to this period. The largest abrupt deterioration in vegetation (positive δ13C excursion) between 17 and 10 kyr BP is a 1 in 5kyr occurrence - An event of a magnitude that was likely encountered and survived by H. floresiensis multiple

  5. Importancia de los estudios fisiológicos en los cultivos de flores de exportación

    Directory of Open Access Journals (Sweden)

    Orozco de Amézquita Martha

    1992-12-01

    Full Text Available La Fisiologla Vegetal estudia el funcionamiento de las plantas y los procesos vitales que regulan su crecimiento, desarrollo y producción. En últimas, las respuestas de los vegetales dependen de lo que ocurre a nivel molecular, de organelos subcelulares, de células, de tejidos y órganos y de las
    interrelaciones entre ellos, todo ésto modulado por
    las condiciones ambientales. De la anterior definición, se deduce la importancia que tiene la investigación de los procesos fisiológicos en el desarrollo de la floricultura. En la actualidad, el manejo de plantas productoras de flores bajo
    invernadero en la Sabana de Bogotá está basado en el interés de los floricultores por mejorar y aumentar
    la calidad de la producción, lo cual ha originado un importante conocimiento emplrico, acompañado del empleo de técnicas recomendadas por expertos internacionales, que han suplido
    los requerimientos necesarios para la producción. Por lo anterior, Arbeláez (1985 opina que un aspecto de vital importancia en el desarrollo futuro de la industria de flores será el poder contar con investigación suficiente que genere la tecnologla adecuada a las necesidades y condiciones colombianas.

  6. Extreme tsunami runup simulation at Babi Island due to 1992 Flores tsunami and Okushiri due to 1993 Hokkido tsunami

    Science.gov (United States)

    Chule Kim, Dong; Choi, Byung Ho; Kim, Kyeong Ok; Pelinovsky, Efim

    2014-05-01

    This study is based on a series of three dimensional numerical modeling experiments to understand the tsunami run-up and inundation process at the circular shape Babi Island in the Indonesia caused by 1992 Flores earthquake tsunami and at Monai valley in Okushiri Island, west part of East (Japan) Sea caused by the 1993 Hokkaido Nansei-Oki earthquake. The wave field in the coastal area is modeled within the framework of fully nonlinear dispersive Reynolds-averaged Navier-Stokes (RANS) equations solved using the FLOW3D code. Boundary conditions for this model were extracted from computed wave characteristics obtained from the 2D tsunami propagation model based on the shallow water equations. This model has shown it effectivity to explain extreme runup characteristics during the 2004 Indian Ocean tsunami and 2011 Japan tsunami (Kim et al, 2013). In case of the 1992 Flores Island tsunami the results of numerical simulation run-up results are compared with field measured run-up heights. It has good agreement with measurement and computational run-up heights. The particle velocity distribution is also computed. In the case of 1993 Okushiri tsunami the numerical simulation reproduces extreme run-up at the Monai valley (31.7 m).

  7. Fungos e nematóides fitopatogênicos associados ao cultivo de flores tropicais em São Luís - MA

    Directory of Open Access Journals (Sweden)

    Diogo Herison Silva Sardinha

    2012-06-01

    Full Text Available Considerando a importância do cultivo de flores tropicais no contexto nacional e internacional, buscou-se realizar um levantamento da ocorrência de fungos e nematóides associados às mesmas, em áreas de cultivos de flores tropicais em São Luís - MA. Foram realizadas visitas periódicas, em intervalos bimestrais, nos locais onde a principal atividade era o cultivo de flores tropicais, para o monitoramento e coleta de plantas ou partes de plantas das espécies: Heliconia spp., Alpinia purpurata e Etlingera elatior com sintomatologia típica de doenças. Realizou-se, ainda, o teste de patogenicidade dos principais fungos detectados como agentes causais das manchas foliares. Os resultados obtidos confirmaram a existência de fungos associados aos cultivos de flores tropicais em São Luís, com destaque para Curvularia eragrostides (78 %, Pestalotiopsis sp. (68 % e Colletotrichum gloeosporioides (47 % como agentes causais de manchas foliares em espécies da família Heliconiaceae, e Curvularia eragrostides (75 %, Pestalotiopsis sp. (37 % em espécies da família Zingiberaceae. Foram registrados oito gêneros de nematóides, tanto na família Heliconiaceae, quanto na Zingiberaceae, destacando-se o gênero Meloidogyne.

  8. Variação no número de glândulas e produção de óleo em flores de Stigmaphyllon paralias A. Juss. (Malpighiaceae Variation in the number of glands and oil production in flowers of Stigmaphyllon paralias A. Juss. (Malpighiaceae

    Directory of Open Access Journals (Sweden)

    Paula Dib de Carvalho

    2005-06-01

    Full Text Available Foi estudada uma população de Stigmaphyllon paralias (Malpighiaceae em Feira de Santana, Bahia, Brasil, visando analisar a variação do número de glândulas e sua produção de óleo nas flores. Dos indivíduos analisados, 76% não variaram o número de glândulas entre suas flores, ocorrendo 41% de indivíduos com flores que possuem 10 glândulas, 31% com oito glândulas e 4% com nove glândulas. Nas flores dos morfos que apresentam oito e nove glândulas, as glândulas ausentes são sempre as da sépala inferior. Centris leprieuri e Epicharis sp. (Apidae: Centridini foram as únicas espécies que visitaram S. paralias, coletando óleo como recompensa. A sépala inferior localiza-se sob o abdome do polinizador quando pousado na flor, tornando-se inacessível à coleta de óleo. Sugerimos que a incapacidade de utilização de algumas glândulas pelos polinizadores possa ter possibilitado o aparecimento de morfos nas populações que não apresentam estas glândulas como caráter adaptativo por gerar economia de recursos na produção de recompensa não utilizada pelo polinizador. Todas as glândulas de todos os morfos são funcionais. As flores dos dois morfos principais com oito e 10 glândulas, produzem a mesma quantidade total de óleo. As glândulas das flores com oito glândulas aumentam a produção em cerca de 20%, compensando a produção total de óleo por flor.A population of Stigmaphyllon paralias (Malpighiaceae was studied in Feira de Santana, Bahia, Brazil. Variation of the number of oil glands and oil production in the flowers were analized. 76% of the individuals did not present variation on the number of glands among their flowers, 41% presented flowers with 10 glands, 31% with eight glands and 4% with nine glands. In the flowers of the morphs with eight or nine glands, the absent glands were always associated to the inferior sepal. Only Centris leprieuri and Epicharis sp. (Apidae: Centridini visited flowers of S. paralias

  9. Evolution des flores et de la végétation Tertiaires en Afrique, au nord de PEquateur

    Directory of Open Access Journals (Sweden)

    E. Boureau

    1983-12-01

    Full Text Available La repartition de la flore Tertiaire en Afrique, três différente de l’actuelle, se comprend si on tient compte de deux facteurs essentiels: la regression des mers épicontinentales vers le nord et la dérive du continent africain. II en résulte qu’á l'Eocêne inférieur, l’équateur se trouvait á environ 1 000 km au nord de sa position actuelle. Ces modifications aboutissent á des transformations importantes de l’environnement climatique et par consequent de la repartition des flores. Cela explique notamment la presence d’une mangrove en Libye avec Sonneratioxylon aubrevillei et en Egypte avec Nipa burtinii.La forêt dense est présente dans le Paléocêne du Tinrhert avec Entandrophragmoxylon normandii (comparable á l’actuel  Entandrophragma angolense. Les formations de foret dense, développées á l’Eocêne, surtout sur le rivage, sont suivies plus au sud, d’une savane qui s’étend davantage á I’Oligocêne et qui peut atteindre la mer. Cependant, on trouve encore en bordure de mer á l’Oligocêne, des espêces de forêt dense comme Entandrophragmoxylon magnieri (comparable á  Entandrophragma candollei espêce qui avoisine des dépóts deltaiques avec de grands troncs qui indiquent une flore plus sêche (Detarioxylon aegyptiacum, Combretoxylon bussonii et Pterocarpoxylon tibestiense (rapproché du Pterocarpus erinaceus de savane, mais parfois accompagnée de troncs de forêt-galerie (Atherospermoxylon aegyptiacum, Monimiacée. Au Miocene, l’assechement continue et la savane progresse. Les Palmiers apparaissent et des galeries forestieres subsistent, mais même á proximité de la mer, le biotope est sec au Miocene inférieur dans le Nord de l’Afrique. Ce n’est que vers le sud que la végétation hygrophile apparait au niveau du Tibesti avec Myristicoxylon vincentii. Ainsi. prês de la position présente de l’Equateur, la mangrove se retrouve au Sénégal dans le Paléogêne du Cap-Vert avec des pollens

  10. Determinação da dissimilaridade genética entre acessos de Capsicum chinense com base em características de flores

    Directory of Open Access Journals (Sweden)

    Carla Sigales de Vasconcelos

    2012-08-01

    Full Text Available As pimentas do gênero Capsicum apresentam grande importância para o mercado de condimentos e para o uso ornamental no Brasil. A estimativa da diversidade genética é importante na escolha de progenitores de programa de melhoramento genético. Este trabalho teve por objetivo verificar a eficiência de descritores multicategóricos de flores para estimar a dissimilaridade genética entre acessos de Capsicum chinense, do Banco Ativo de Germoplasma Capsicum, da Embrapa Clima Temperado. O experimento foi realizado no período de agosto de 2009 a março de 2010, no campo experimental da Embrapa Clima Temperado, em blocos ao acaso, utilizando-se 22 acessos, com dez plantas por parcela. Para a caracterização morfológica das flores, foram avaliadas cinco flores de cada planta, de dez plantas por acesso. Foram utilizados 15 descritores, sendo cinco quantitativos e dez qualitativos multicategóricos. Foram realizadas análises de comparação de médias, utilizando-se agrupamento pelos métodos UPGMA e de Tocher, para os dados quantitativos, e agrupamento pelo método de Tocher, para os dados qualitativos. Os acessos estudados apresentam ampla diversidade genética em relação a descritores de flores, existindo grande variabilidade entre os acessos avaliados, o que recomenda seu uso em programas de melhoramento genético. O uso de descritores multicategóricos de flores é eficiente para estimar a dissimilaridade genética entre acessos de Capsicum chinense.

  11. Realization of Fractal Affine Transformation

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This paper gives the definition of fractal affine transformation and presents a specific method for its realization and its cor responding mathematical equations which are essential in fractal image construction.

  12. Bounded contractions for affine buildings

    OpenAIRE

    Bestvina, Mladen; Savin, Gordan

    2017-01-01

    We consider affine buildings with refined chamber structure. For each vertex in the refined chamber structure we construct a contraction, based at the vertex, that is used to prove exactness of Schneider-Stuhler resolutions of arbitrary depth.

  13. Affinity chromatography of phosphorylated proteins.

    Science.gov (United States)

    Tchaga, Grigoriy S

    2008-01-01

    This chapter covers the use of immobilized metal ion affinity chromatography (IMAC) for enrichment of phosphorylated proteins. Some requirements for successful enrichment of these types of proteins are discussed. An experimental protocol and a set of application data are included to enable the scientist to obtain high-yield results in a very short time with pre-packed phospho-specific metal ion affinity resin (PMAC).

  14. Oriented angles in affine space

    Directory of Open Access Journals (Sweden)

    Włodzimierz Waliszewski

    2004-05-01

    Full Text Available The concept of a smooth oriented angle in an arbitrary affine space is introduced. This concept is based on a kinematics concept of a run. Also, a concept of an oriented angle in such a space is considered. Next, it is shown that the adequacy of these concepts holds if and only if the affine space, in question, is of dimension 2 or 1.

  15. Abundancia de colibríes y uso de flores en un bosque templado del sureste de México

    OpenAIRE

    Partida Lara, Ruth; Enríquez, Paula L.; Rangel-Salazar, José Luis; Lara, Carlos; Martínez Ico, Miguel

    2012-01-01

    La abundancia de los colibríes puede variar por la fenología de floración de las plantas de las que se alimentan. Sin embargo, la información sobre la interacción colibrí-flor es limitada en ambientes tropicales de montaña. En este estudio se evaluó la abundancia de colibríes con redes de niebla y se registró la fenología de floración mensual de las flores visitadas por los colibríes en tres ambientes (bosque de encino, de neblina y matorral) en la Reserva Ecológica Huitepec, Chiapas, México ...

  16. CLASTS OF UPPERMOST ALBIAN (VRACONIAN LIMESTONE IN THE EOCENE CUCCURU 'E FLORES CONGLOMERATE OF THE M. ALBO MASSIF (EASTERN SARDINIA

    Directory of Open Access Journals (Sweden)

    IGINIO DIENI

    2012-03-01

    Full Text Available Rare clasts of richly fossiliferous uppermost Albian (Vraconian auctt. glauconitic and phosphatic, ammonite-bearing limestone have been found in the Eocene Cuccuru ’e Flores Conglomerate in the area of M. Albo massif (eastern Sardinia. The limestone is wholly comparable in facies and fossil assemblage to the classical outcrop known in the Orosei area. The fossil content includes also brachiopods and abundant planktonic foraminifers of the Thalmanninella (formerly Rotalipora appenninica Zone. In the palaeontological part the brachiopods Orbirhynchia parkinsoni and Capillithyris capillata are described and discussed. Vraconian highly condensed deposits, characterized by basal erosional gaps of variable importance, have particular relevance, being known to be widely distributed in the northern Tethyan margin with common characteristics, such as authigenic glauconite, phosphatic nodules and a rich outer-shelf fauna. 

  17. Mercados públicos y competitividad: El Palmar y Las Flores de Ciudad Nezahualcóyotl

    Directory of Open Access Journals (Sweden)

    Laura Elena Garza-Bueno

    2013-01-01

    Full Text Available Con el propósito de modernizar los mercados públicos, el gobierno del Estado de México en alianza con el Colegio de Postgraduados estableció un programa de formación de recursos humanos. La metodología consistió en incorporar a los locatarios de los mercados El Palmar y Las Flores de Ciudad Nezahualcóyotl a un proceso de reflexión sobre las ventajas competitivas que ellos consideran poseer y las que señala su clientela. Estas últimas se obtuvieron mediante una encuesta. El artículo presenta los resultados de la reflexión y de la encuesta, así como de las acciones acordadas a partir de la confrontación de ambos resultados.

  18. Abundancia de colibríes y uso de flores en un bosque templado del sureste de México

    Directory of Open Access Journals (Sweden)

    Ruth Partida Lara

    2012-12-01

    Full Text Available La abundancia de los colibríes puede variar por la fenología de floración de las plantas de las que se alimentan. Sin embargo, la información sobre la interacción colibrí-flor es limitada en ambientes tropicales de montaña. En este estudio se evaluó la abundancia de colibríes con redes de niebla y se registró la fenología de floración mensual de las flores visitadas por los colibríes en tres ambientes (bosque de encino, de neblina y matorral en la Reserva Ecológica Huitepec, Chiapas, México de enero a agosto 2010. Cuatro especies de colibríes (Hylocharis leucotis, Lampornis amethystinus, Lamprolaima rhami y Eugenes fulgens se registraron y sus abundancias variaron entre ambientes (H3.8=14.8, p=0.001. Siete especies de plantas fueron visitadas por los colibríes, y presentaron una mayor floración formando parches durante la temporada de secas. En el matorral se concentró el mayor número de especies de plantas con flores. Fuchsia paniculata presentó el mayor periodo de floración aunque solo fue visitada por H. leucotis. Passiflora membranacea fue la única especie visitada por las cuatro especies de colibríes. La única asociación positiva fue la abundancia de E. fulgens con la floración de P. membranacea (rS=0.93, p=0.02. Las fluctuaciones de las abundancias de colibríes en este estudio están en cierta forma determinadas por las interacciones del recurso floral y su distribución en el ambiente

  19. ANTRACNOSE DO CAQUIZEIRO CAUSADA POR Colletotrichum horii: INCIDÊNCIA EM RAMOS, FOLHAS, FLORES E FRUTOS EM CAMPO

    Directory of Open Access Journals (Sweden)

    RENATO REZENDE YOUNG BLOOD

    2015-06-01

    Full Text Available O objetivo deste trabalho foi avaliar a incidência em várias partes da planta e o desenvolvimento da antracnose do caquizeiro causada por Colletotrichum horiinas cultivares Fuyu e Kakimel produzidas sob os sistemas orgânico e convencional, respectivamente, nas safras de 2010/2011 e 2011/2012, em Campina Grande do Sul, Paraná, Brasil. Em cada pomar, 10 plantas foram selecionadas aleatoriamente, e 10 ramos do ano por planta, distribuídos ao redor dacopa, foram marcados para as avaliações de incidência de antracnose em ramos e folhas, a cada 15 dias. A quantificação de frutos caídos com ou sem sintomas da doença foi a cada 15 dias, durante o período de crescimento de frutos até a colheita, relacionada com a produção total. C. horii em flores foi avaliada em campo e também após incubação no laboratório. Infecção latente foi observada em frutos verdes coletados aos 90; 120 e 150 dias após a floração. Em ambas as safras, observou-se a queda de frutos com sintomas de antracnose entre os meses de janeiro e abril. C. horii é capaz de infectar flores, permanecer latente e provocar sintomas de antracnose em frutos imaturos. Frutos colhidos sadios apresentaram sintomas em pós-colheita após a incubação.

  20. Organización de la comunidad de colibríes ermitaños (Trochilidae phaethorninae) y sus flores en bosques de tierra firme del Parque Nacional Natural Amacayacu (Amazonas, Colombia)

    OpenAIRE

    Rodríguez Flores Claudia Isabel; Stiles Frank Gary

    2004-01-01

    Se determinó la organización de la comunidad de colibríes ermitaños y sus recursos en bosques de tierra firme de la Amazonia colombiana, a partir de observaciones directas a las flores, cargas de polen de los ermitaños, medidas morfológicas de colibríes y flores, y conteo de flores
    en cinco sitios diferentes. La comunidad la conformaron siete especies de ermitaños (Phaethornis malaris, P. hispidus, P. bourcieri, P. atrimentalis, P. ruber, Glaucis hirsuta y Threnetes leucurus), y 44...

  1. Repartição de nutrientes nas flores, folhas e ramos da laranjeira cultivar Natal Repartition of nutrients in citrus flowers, leaves and branches

    Directory of Open Access Journals (Sweden)

    Eurípedes Malavolta

    2006-12-01

    Full Text Available As plantas cítricas produzem elevado número de flores, porém pequena porcentagem chega a fruto maduro. A fixação é influenciada por diversos fatores, com destaque para os nutricionais orgânicos e minerais. O objetivo do trabalho foi verificar a repartição de macro e micronutrientes nas flores, folhas e ramos de laranjeira e a contribuição nutricional das flores para os demais órgãos. Plantas de Citrus sinensis L., cultivar Natal sobre porta-enxerto de limoeiro cravo de 10 anos de idade, provenientes de pomar comercial, foram amostradas por ocasião do fluxo primaveril e separadas em flores, folhas e ramos. As flores representam dreno tanto para compostos orgânicos quanto para macro e micronutrientes. Sua massa seca na antese se iguala às das folhas e é maior que a dos ramos. A maior proporção de Ca, Mg e de Ni das três partes encontram-se nas flores de onde, possivelmente, passam em parte para o fruto em desenvolvimento. Sugere-se que aplicações foliares de cálcio, magnésio e níquel, em condições de deficiência, poderiam aumentar a produção através do seu efeito no florescimento.Citrus plants produce a number of flowers, but just a few of them however, become mature fruits. Many factors, as well as organic and inorganic nutrients, influence prebloom and flowers setting. The objective of this work was to evaluate the repartition of macro and micronutrients in citrus flowers, leaves and branches. Branches of "Natal" sweet orange (Citrus sinensis L. grafted on Rangpur lime rootstock were collected and separated in flowers, leaves and wood during anthesis. Orange flowers represent a drain for organic compounds and macro and micronutrients as well. Their dry matter on anthesis is equal to that of leaves and higher than that of the branches. The highest proportion of Ca, Mg and Ni of the three parts is found in the flowers where possibly migrate in part, into the developing fruits. It is thought that leaf sprays of

  2. Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling.

    Science.gov (United States)

    Hackel, Benjamin J; Kapila, Atul; Wittrup, K Dane

    2008-09-19

    The 10th type III domain of human fibronectin (Fn3) has been validated as an effective scaffold for molecular recognition. In the current work, it was desired to improve the robustness of selection of stable, high-affinity Fn3 domains. A yeast surface display library of Fn3 was created in which three solvent-exposed loops were diversified in terms of amino acid composition and loop length. The library was screened by fluorescence-activated cell sorting to isolate binders to lysozyme. An affinity maturation scheme was developed to rapidly and broadly diversify populations of clones by random mutagenesis as well as homologous recombination-driven shuffling of mutagenized loops. The novel library and affinity maturation scheme combined to yield stable, monomeric Fn3 domains with 3 pM affinity for lysozyme. A secondary affinity maturation identified a stable 1.1 pM binder, the highest affinity yet reported for an Fn3 domain. In addition to extension of the affinity limit for this scaffold, the results demonstrate the ability to achieve high-affinity binding while preserving stability and the monomeric state. This library design and affinity maturation scheme is highly efficient, utilizing an initial diversity of 2x10(7) clones and screening only 1x10(8) mutants (totaled over all affinity maturation libraries). Analysis of intermediate populations revealed that loop length diversity, loop shuffling, and recursive mutagenesis of diverse populations are all critical components.

  3. Gyriosomus granulipennis Pizarro-Araya & Flores 2004 (Coleoptera: Tenebrionidae: An extreme case to preserve Gyriosomus granulipennis Pizarro-Araya & Flores 2004 (Coleóptera: Tenebrionidae: Un caso extremo a conservar

    Directory of Open Access Journals (Sweden)

    JAIME PIZARRO-ARAYA

    2012-09-01

    Full Text Available The Choros Archipelago includes three islands: Choros, Damas and Gaviota and it is part of The Pingüino de Humboldt National Reserve. These insular ecosystems are within the Chilean transitional coastal (25°-32° S. Prior researches in the archipelago reported a species of Tenebrionidae (Coleoptera endemic to Choros island (29°15' S, 71°32' W described as Gyriosomus granulipennis Pizarro-Araya & Flores. The objective of this paper is to evaluate the vulnerability of this species in the archipelago through Conservation Priority Index (CPI, Environmental Ministery of Chile (MMA and Red List of IUCN. We concluded that G. granulipennis is Endangered by CPI index, and Vulnerable by MMA of Chile. Additionally, this species can be classiffied with Deficient Data (DD by IUCN because many of data are impossible or difficult to obtain for insects and can overestimate or underestimate the risk of extinction of this species. We consider important to monitoring the continuity of this species and the protection of habitat, for which we propose not allow access the tourists and eradication of European rabbit.El archipiélago de Los Choros, conformado por las islas Choros, Damas y Gaviota forma parte de la Reserva Nacional Pingüino de Humboldt y está situado dentro del desierto costero transicional de Chile (25°-32° S. Estudios recientes realizados en el archipiélago dan cuenta de una especie endémica de Tenebrionidae (Coleoptera de la isla Choros (29°15' S, 71°32' O descripta como Gyriosomus granulipennis Pizarro-Araya & Flores. El objetivo del presente trabajo es evaluar la prioridad de conservación de esta especie en el archipiélago mediante el análisis del Índice de Prioridad de Conservación (CPI, clasificación del Ministerio de Medio Ambiente (MMA de Chile y lista roja de la IUCN. Nuestros resultados sostienen que esta especie puede ser catalogada en categoría En peligro por el índice CPI y Vulnerable según el MMA. Según criterios

  4. Búsqueda y reconocimiento de los enemigos naturales y hospedantes alternos de las principales plagas en flores bajo invernadero en la Sabana de Bogotá

    Directory of Open Access Journals (Sweden)

    Briceño Jorge A.

    1989-06-01

    Full Text Available

    Las plagas que atacan cultivos de flores bajo invernadero son cada vez más importantes por la gravedad de su daño y por la alta densidad con que suelen presentarse. Para su control se ha acudido principalrnente a la utilización de productos químicos, lo cual conduce a un aumento en los costos de producción, a contaminar el medio ambiente, a afectar la salud humana y a crear resistencia de los insectos a los insecticidas. Debido a esto, es necesario incluir dentro de los programas de control a los reguladores naturales de las plagas: parasitoides, depredadores y microorganismos entornogenos. En el presente trabajo se registran los enemigos naturales más importantes de las principales plagas en flores bajo invernadero (crisantemo, rosa y clavel.

  5. Piscadelas de caveiras: a escatologia do Jardim das Flores Skull winks: the eschatology of the Garden of Flowers

    Directory of Open Access Journals (Sweden)

    John C. Dawsey

    2007-11-01

    Full Text Available No Jardim das Flores, na periferia de uma cidade do interior paulista, moradores interpretam o seu mundo por meio de histórias sobre o céu e o inferno, e a destruição e recriação do mundo. Como interpretar essas interpretações? A partir dessa questão a antropologia de Geertz propõe-se a fazer uma "descrição densa" em que seja possível distinguir um piscar de olhos de uma piscadela marota. As histórias que se contam no Jardim das Flores, porém, não são meras interpretações. Nelas se alojam vontades de interromper o próprio curso do mundo. Ao dizerem algo sobre o mundo, elas irrompem como provocações capazes de suscitar um abrir e fechar dos olhos, com efeitos de despertar. Por meio de imagens carregadas de tensões, uma descrição densa também adquire as qualidades de uma descrição tensa, um assombro. Não seriam as elipses, incoerências e emendas suspeitas - onde um texto parece desmanchar - os sinais do "baixo corporal" do texto que chamamos cultura? Talvez nesses lugares, como as histórias do Jardim das Flores revelam, encontrem-se os subsolos mais férteis de um texto, ou, ainda, o seu fundo escatológico.In the Garden of Flowers, a peripheral district of a city of the interior of São Paulo, people interpret their world, among other ways, by telling stories about heaven and earth, and the destruction and recreation of the world. How should one interpret these interpretations? As a way for dealing with this question, Geertz developed the notion of 'thick description,' by which one may distinguish a twitch from a wink. The stories told in the Garden of Flowers are not mere interpretations, however. They emerge from the will to interrupt the very course of the world. As they say something about the world, they also erupt as provocations, with awakening effects, causing one's eyes to close and reopen. By means of tension-filled images, 'thick description' may also acquire the qualities of tense description, provoking

  6. Affine Contractions on the Plane

    Science.gov (United States)

    Celik, D.; Ozdemir, Y.; Ureyen, M.

    2007-01-01

    Contractions play a considerable role in the theory of fractals. However, it is not easy to find contractions which are not similitudes. In this study, it is shown by counter examples that an affine transformation of the plane carrying a given triangle onto another triangle may not be a contraction even if it contracts edges, heights or medians.…

  7. Gravity theory through affine spheres

    Science.gov (United States)

    Minguzzi, E.

    2017-08-01

    In this work it is argued that in order to improve our understanding of gravity and spacetime our most successful theory, general relativity, must be destructured. That is, some geometrical assumptions must be dropped and recovered just under suitable limits. Along this line of thought we pursue the idea that the roundness of the light cone, and hence the isotropy of the speed of light, must be relaxed and that, in fact, the shape of light cones must be regarded as a dynamical variable. Mathematically, we apply some important results from affine differential geometry to this problem, the idea being that in the transition we should preserve the identification of the spacetime continuum with a manifold endowed with a cone structure and a spacetime volume form. To that end it is suggested that the cotangent indicatrix (dispersion relation) must be described by an equation of Monge-Ampère type determining a hyperbolic affine sphere, at least whenever the matter content is negligible. Non-relativistic spacetimes fall into this description as they are recovered whenever the center of the affine sphere is at infinity. In the more general context of Lorentz-Finsler theories it is shown that the lightlike unparametrized geodesic flow is completely determined by the distribution of light cones. Moreover, the transport of lightlike momenta is well defined though there could be no notion of affine parameter. Finally, we show how the perturbed indicatrix can be obtained from the perturbed light cone.

  8. Feeding behavior of hummingbirds and perching birds on Erythrina speciosa Andrews (Fabaceae flowers in an urban area, Londrina, Paraná, Brazil Comportamento alimentar de beija-flores e Passeriformes nas flores de Erytrhina speciosa Andrews (Fabaceae em uma área urbana de Londrina, Paraná, Brasil

    Directory of Open Access Journals (Sweden)

    Luciana Baza Mendonça

    2006-03-01

    Full Text Available Nine species of birds - seven hummingbirds (Trochilidae and two Passeriformes - were observed visiting the flowers of Erythrina speciosa Andrews (Fabaceae, a hummingbird-pollinated species present on the campus of Londrina State University, Paraná State, Brazil. Nectar in bagged flowers bore little relationship with nectar in flowers opened to foragers either regarding quantity or diurnal pattern of availability. Birds were more frequent early in the morning and their activity on flowers further declined, apparently following the pattern of nectar availability. The manner to which birds probed the flowers and, in consequence, their role on pollination were greatly determined by morphological traits and approaching behavior of birds. E. speciosa seemed best suited for pollination by long-billed hummingbirds but some short to medium-billed species may play some role on its pollination.Nove espécies de aves - sete beija-flores (Trochilidae e duas aves Passeriformes - foram observados visitando as flores de Erythrina speciosa Andrews (Fabaceae, uma espécie polinizada por beija-flores presente no campus da Universidade Estadual de Londrina, Paraná, Brasil. O néctar em flores ensacadas apresentou pouca relação com aquele em flores expostas aos visitantes, tanto em termos de quantidade como em temos de padrão diurno de disponibilidade. As aves foram mais freqüentes de manhã e sua atividade nas flores diminuiu no transcorrer do dia, coincidindo com o padrão de disponibilidade de néctar. O comportamento de visita das aves e, em conseqüência, sua atuação na polinização da espécie foram em grande parte determinadas por características morfológicas e comportamentais destas. E. speciosa parece ser adaptada para polinização por beija-flores de bicos longos, embora espécies com bicos de comprimento curto a médio possam ter algum papel em sua polinização.

  9. Fenologia do florescimento e características do perfume das flores de Passiflora quadrangularis l. (maracujá-melão

    Directory of Open Access Journals (Sweden)

    Daniel Antonio Villamil Montero

    2013-08-01

    Full Text Available Passiflora quadrangularis L. é uma espécie originária do neotrópico, conhecida no Brasil como maracujá-melão devido ao tamanho e formato dos seus frutos. Tem sido amplamente disseminada nas regiões tropicais do mundo onde é produzida em pequena escala para comercialização dos frutos, o que ocorre bem próximo às regiões de cultivo, em função da dificuldade de conservação pós-colheita. As plantas são trepadeiras bastante vigorosas, com flores abundantes, grandes e perfumadas, o que amplia o seu valor e a torna particularmente interessante para caramanchões e cercas-vivas. O uso efetivo de passifloras no mercado de plantas ornamentais depende de estudos da fenologia floral. Neste trabalho foram estudadas algumas características da fenologia floral e o perfume das flores de P. quadrangularis, sob cultivo protegido. São apresentados os dados relativos ao período de floração, picos de florescimento e intensidade relativa das flores, bem como algumas características do perfume floral. Conclui-se que a espécie representa uma nova alternativa de cultivo para fins ornamentais, por apresentar múltiplas flores em antese simultânea, abundantes, grandes, fragrantes e coloridas, com longo período de floração no ano, além de frutos comestíveis, folhas exuberantes e medicinais que oferecem amplo sombreamento para áreas externas de lazer e/ou outras plantas cultivadas.

  10. Análise de amostras de flores de Calêndula (Calendula officinalis L., Asteraceae comercializadas na grande Curitiba

    Directory of Open Access Journals (Sweden)

    Lais Mondadori Otramario Santos

    2015-10-01

    Full Text Available A espécie Calendula officinalis L. é uma planta herbácea pertencente à família Asteraceae, suas flores apresentam propriedades antimicrobianas, emolientes, antiinflamatórias e tonificantes da pele. Os flavonoides são utilizados como marcadores para avaliar a qualidade da droga vegetal. O objetivo do presente trabalho foi avaliar a identidade e qualidade de seis amostras de flores de C. officinalis L. comercializadas na Grande Curitiba (PR. Foram realizados os ensaios de identificação macroscópica e de pureza, determinação de flavonoides, perfil do extrato etanólico em cromatografia em camada delgada, avaliação das atividades antioxidante e atividade antibacteriana sobre Staphylococcus aureus ATCC 25923. Todas as seis amostras analisadas foram identificadas como C. officinalis L. e foram aprovadas no perfil cromatográfico, porém não atenderam aos requisitos farmacopeicos de pureza e teor de flavonoides, fatores que contribuíram para a diminuição da atividade antioxidante e antibacteriana. A má qualidade de plantas medicinais, decorrente de processos produtivos inadequados, pode ocasionar ausência ou diminuição do efeito terapêutico esperado, além de possíveis efeitos tóxicos.Palavras chaves: Calendula officinalis L. Flavonoides. Controle da Qualidade. Cromatografia em camada delgada. Atividade Antioxidante. Atividade Antibacteriana. ABSTRACT Calendula officinalis L., is an herbaceous plant belonging to the family Asteraceae, its flowers have antimicrobial, emollient, anti-inflammatory and toning of the skin properties. Flavonoids are used as chemical markers to evaluate the quality of plant drug. The aim of this study was to evaluate the identity and quality of six samples of C. officinalis L. flowers commercialized in Curitiba City and Metropolitan Area (State of Paraná, Brazil. Tests of macroscopic identification, purity, determination of flavonoids were performed, in addition to the profile of the ethanolic

  11. Descripción del uso y manejo de plaguicidas en las empresas de flores afiliadas a Asocolflores.

    Directory of Open Access Journals (Sweden)

    Marcela E. Varona

    2005-09-01

    Full Text Available Introducción. En Colombia, la exposición a plaguicidas se ha convertido en un problema de salud pública debido al incremento de la demanda; esto ha ocasionado impacto en la salud de la población y en el ambiente. Objetivo. Describir los plaguicidas empleados y determinar su uso y manejo en las empresas de flores en la sabana de Bogotá y Rionegro (Antioquia afiliadas a la Asociación Colombiana de Exportadores de Flores, Asocolflores. Materiales y métodos. Se realizó un estudio descriptivo en 84 empresas estratificadas por ubicación geográfica y por tamaño. Se recolectó información de la empresa y del trabajador, y se realizó una observación detallada del proceso de fumigación y utilización de los plaguicidas. Se llevó a cabo un análisis univariado, bivariado y la exploración de posibles asociaciones. Resultados. El 39,4% de los trabajadores de las empresas incluidas en el estudio pertenecían al sexo masculino y el 60,6% al femenino. Respecto a la categoría toxicológica, el 14,3% de los plaguicidas pertenecía a la categoría I, el 14,4% a la II, el 52,0% a la categoría III y el restante, 19,2%, a la categoría IV. Los plaguicidas más utilizados fueron los ditiocarbamatos con 11,7%. Los equipos más empleados para la aplicación de los plaguicidas eran la bomba móvil (92,8% y la lanza (92,9%. El seguimiento de la exposición a plaguicidas por pruebas de laboratorio, se realizaba por medio de la colinesterasa mediante la técnica de Michel-Aldrige en el 85,9% de las empresas. Conclusión. Este estudio describe la forma como se utilizan los plaguicidas en la industria floricultora en Colombia. Se hacen recomendaciones para mejorar su manejo y se proponen medidas para reducir la exposición de los trabajadores.

  12. El extracto etanólico de las flores de Laccopetalum giganteum (pacra-pacra aumenta la fertilidad en ratas

    Directory of Open Access Journals (Sweden)

    Jorge Arroyo

    2007-09-01

    Full Text Available Objetivos: Determinar si la administración por vía oral del extracto etanólico de flores de Laccopetalum giganteum (Pacra-pacra en ratas normales aumenta la fertilidad. Diseño: Estudio experimental. Lugar: Facultad de Medicina y Facultad de Farmacia y Bioquímica, Universidad Nacional Mayor de San Marcos. Material biológico: Ratas. Intervenciones: Cuarentiocho animales fueron divididos aleatoriamente en 2 grandes grupos, de 24 cada uno. El primero fue control, con solución salina fisiológica (SSF 5 mL/kg y el segundo con extracto vía oral, 300 mg/kg, durante 15 días. Cada grupo consideró 6 hembras y 6 machos juntos, y 6 hembras y 6 machos separados. Los animales que estuvieron juntos fueron sacrificados, para observar la presencia de fetos en el útero; y a los animales que estuvieron separados, se les extrajo muestra de sangre, para conocer el nivel de testosterona en machos y LH, FSH, estrógenos y progesterona en hembras, expresándose en µg/dL; el dosaje hormonal se realizó por el método de electroquimioluminiscencia. Asimismo, se determinó GOT, GPT, urea y creatinina, según las técnicas utilizadas en el laboratorio clínico. Principales medidas de resultados: Gravidez, FSH, LH, estrógenos y progesterona en ratas hembras; testosterona en ratas machos. Resultados: Los flavonoides, compuestos fenólicos y taninos estuvieron en mayor cantidad en el extracto etanólico. El 100% de ratas que recibió el extracto etanólico de la planta y estuvo junto a los machos resultó grávida; y, las separadas que recibieron el mismo extracto, presentaron incremento de FSH en las hembras y testosterona en los machos, comparativamente a los controles respectivos. Los niveles de GOT, GPT, urea y creatinina se encontraron dentro de los límites aceptados. Conclusiones: En condiciones experimentales, el extracto etanólico de las flores de Laccopetalum giganteum (pacra-pacra incrementó la fertilidad en ratas normales.

  13. Theoretical proton affinity and fluoride affinity of nerve agent VX.

    Science.gov (United States)

    Bera, Narayan C; Maeda, Satoshi; Morokuma, Keiji; Viggiano, Al A

    2010-12-23

    Proton affinity and fluoride affinity of nerve agent VX at all of its possible sites were calculated at the RI-MP2/cc-pVTZ//B3LYP/6-31G* and RI-MP2/aug-cc-pVTZ//B3LYP/6-31+G* levels, respectively. The protonation leads to various unique structures, with H(+) attached to oxygen, nitrogen, and sulfur atoms; among which the nitrogen site possesses the highest proton affinity of -ΔE ∼ 251 kcal/mol, suggesting that this is likely to be the major product. In addition some H(2), CH(4) dissociation as well as destruction channels have been found, among which the CH(4) + [Et-O-P(═O)(Me)-S-(CH(2))(2)-N(+)(iPr)═CHMe] product and the destruction product forming Et-O-P(═O)(Me)-SMe + CH(2)═N(+)(iPr)(2) are only 9 kcal/mol less stable than the most stable N-protonated product. For fluoridization, the S-P destruction channel to give Et-O-P(═O)(Me)(F) + [S-(CH(2))(2)-N-(iPr)(2)](-) is energetically the most favorable, with a fluoride affinity of -ΔE ∼ 44 kcal. Various F(-) ion-molecule complexes are also found, with the one having F(-) interacting with two hydrogen atoms in different alkyl groups to be only 9 kcal/mol higher than the above destruction product. These results suggest VX behaves quite differently from surrogate systems.

  14. Training for Future Esp Trainers: Evaluating the Training of Trainers (TOT Program in Labuan Bajo, Manggarai Barat, Flores

    Directory of Open Access Journals (Sweden)

    Irfan Rifai

    2013-04-01

    Full Text Available By cooperating with Yayasan Komodo Kita and Mandiri Bank, English department of Binus University was chiefly in charge of a 15 day Training Of Trainers (TOT program for 24 participants prepared for teaching English in Labuan Bajo, Flores. The training was aimed to prepare already fluent- in – English- teachers, tour guides, and university graduates with the right tools and method in teaching English. To assess the program, a set of evaluation questionnaire was given to the participants to know their responses on the training material, the trainers, and the program by using Likert’s scale type questions. An observational record was also used as a tool to measure participants’ achievement. The questionnaire reveals that the participants respond positively to the program and the material and favor the approaches made by the trainers during the training. However, the training shows various results in participants’ performance. It is assumed that the non teaching background of the majority of participants and the level of English as two key factors influencing their performance.  

  15. Jenis dan Status Konservasi Ikan Hiu yang Tertangkap di Tempat Pelelangan Ikan (TPI Labuan Bajo, Manggarai Barat, Flores

    Directory of Open Access Journals (Sweden)

    Ismail Syakurachman Alaydrus

    2016-03-01

    Full Text Available The study aimed to determine the types of sharks are caught, sold and conservation status in the fish auction place (TPI Labuan Bajo, West Manggarai, Flores, East Nusa Tenggara have been conducted in February and March 2014 in Labuan Bajo. The research method was the survey method and used Market Survey sampling techniques and identification by Rapid Assessment method. Descriptively analyzed data, displayed in the form of narration and a table. Based on the results of the study, found 114 individual sharks, 55 individual males, 59 females were classified into three orders, namely Orectolobiformes, Lamniformes, and Carcharhiniformes; 4 families that Carcharhinidae, Odontaspididae, Rhynchobatidae, and Ginglymostomatidae; 5 genera namely Carcharhinus, Triaenodon, Rhyncobatus, Prionace, and Rhizoprionodon and 9 types of sharks that Carcharhinus melanopterus, Triaenodon obesus, Carcharhinus limbatus, Carcharhinus taurus, Carcharhinus amblyrhynchos, Rhynchobatus australiae, Prionace glauca, Rhizoprionodon acutus, and Nebrius ferrugineus. Based on the state of conservation, shark found in Labuan Bajo TPI classified Vulnerable and Near Threatened, the dominant type of shark found is Carcharhinus melanopterus (91 fishes while the least was found is Rhynchobatus australiae, Prionace glauca, Rhizoprionodon acutus, and Nebrius ferrugineus (each 1 individual.

  16. UJI COBA PENEBARAN JASAD HAYATI NEMATODA ROMANOMERMIS IYENGARI DI PERINDUKAN VEKTOR MALARIA DAN FILARIASIS DI FLORES TIMUR

    Directory of Open Access Journals (Sweden)

    Widiarti Widiarti

    2012-09-01

    Full Text Available A study to evaluate the effect of R. iyengari, a parasitic nematod as a biological agent of vector control toward mosquito larvae in the sandpool, an ideal breeding places for malaria and fdariasis vectors, was conducted in East Flores. The aim of the present study was to determine : (1. The adaptability and recycling ability of post parasites stage of the nematode in the sandpool. (2. The ability of pre parasites (infective stage to parasitize Cx. quinquefasciatus (laboratory larvae in centinel cage and An. barbirostris (natural larvae/sandpool. The distribution of R. iyengari post parasites at a dosage of500 nematodes/m2 revealed that the nematodes mature to adults, mated and layed eggs (adapted, however recycling could not be observed yet. The infection rate of Cx. quinquefasciatus sentinel cages after release through dissections was observed in 70.55%, 48.68% and 3.64% respectively after 1 month, 2 months and 3 months. The mean monthly infection level for An. barbirostris was 28.24%, 16.66% and 31.25% for 1 month, 2 months and 3 months post release dissections respectively.

  17. Electron affinity of chlorine dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Babcock, L.M.; Pentecost, T.; Koppenol, W.H. (Louisiana State Univ., Baton Rouge (USA))

    1989-12-14

    The flowing afterglow technique was used to determine the electron affinity of chlorine dioxide. A value of 2.37 {plus minus} 0.10 eV was found by bracketing between the electron affinities of HS* and SF{sub 4} as a lower limit and that of NO{sub 2} as an upper limit. This value is in excellent agreement with 2.32 eV predicted from a simple thermodynamic cycle involving the reduction potential of the ClO{sub 2}/ClO{sub 2}{sup {minus}} couple and a Gibbs hydration energy identical with that of SO{sub 2}{sup {sm bullet}{minus}}.

  18. The electron affinity of tungsten

    Energy Technology Data Exchange (ETDEWEB)

    Lindahl, A.O.; Andersson, P.; Klason, P.; Hanstorp, D. [Department of Physics, University of Gothenburg (Sweden); Diehl, C. [Institut fur Physik, Johannes Gutenberg-Universitat, Mainz (Germany); Present Address: Max-Planck-Institut fur Kernphysik, Heidelberg (Germany); Forstner, O. [Faculty of Physics, University of Vienna, Wien (Austria)

    2010-11-15

    The electron affinity of tungsten has been measured using laser photodetachment threshold spectroscopy in a collinear geometry. The electron affinity was determined to 6583.6(6) cm{sup -1} by observing the onset of the process when W{sup -} ions in the 5d{sup 5}6s{sup 2} {sup 6}S{sub 5/2} ground state are photo-detached producing neutral W atoms in the 5d{sup 4}6s{sup 2} {sup 5}D{sub 0} ground state. The measured value is in agreement with previous measurements and improves the accuracy by almost two orders of magnitude. Further, a photodetachment signal below the ground state photodetachment threshold was found, which indicates the existence of a bound excited state in W{sup -}. (authors)

  19. Affine density in wavelet analysis

    CERN Document Server

    Kutyniok, Gitta

    2007-01-01

    In wavelet analysis, irregular wavelet frames have recently come to the forefront of current research due to questions concerning the robustness and stability of wavelet algorithms. A major difficulty in the study of these systems is the highly sensitive interplay between geometric properties of a sequence of time-scale indices and frame properties of the associated wavelet systems. This volume provides the first thorough and comprehensive treatment of irregular wavelet frames by introducing and employing a new notion of affine density as a highly effective tool for examining the geometry of sequences of time-scale indices. Many of the results are new and published for the first time. Topics include: qualitative and quantitative density conditions for existence of irregular wavelet frames, non-existence of irregular co-affine frames, the Nyquist phenomenon for wavelet systems, and approximation properties of irregular wavelet frames.

  20. Lectin affinity chromatography of glycolipids

    Energy Technology Data Exchange (ETDEWEB)

    Torres, B.V.; Smith, D.F.

    1987-05-01

    Since glycolipids (GLs) are either insoluble or form mixed micelles in water, lectin affinity chromatography in aqueous systems has not been applied to their separation. They have overcome this problem by using tetrahydrofuran (THF) in the mobile phase during chromatography. Affinity columns prepared with the GalNAc-specific Helix pomatia agglutinin (HPA) and equilibrated in THF specifically bind the (/sup 3/H)oligosaccharide derived from Forssman GL indicating that the immobilized HPA retained its carbohydrate-binding specificity in this solvent. Intact Forssman GL was bound by the HPA-column equilibrated in THF and was specifically eluted with 0.1 mg/ml GalNAc in THF. Purification of the Forssman GL was achieved when a crude lipid extract of sheep erythrocyte membranes was applied to the HPA-column in THF. Non-specifically bound GLs were eluted from the column using a step gradient of aqueous buffer in THF, while the addition of GalNAc was required to elute the specifically bound GLs. Using this procedure the A-active GLs were purified from a crude lipid extract of type A human erythrocytes in a single chromatographic step. The use of solvents that maintain carbohydrate-binding specificity and lipid solubility will permit the application of affinity chromatography on immobilized carbohydrate-binding proteins to intact GLs.

  1. Affine connections on involutive G-structures

    OpenAIRE

    Merkulov, Sergey A.

    1995-01-01

    This paper is a review of the twistor theory of irreducible G-structures and affine connections. Long ago, Berger presented a very restricted list of possible irreducibly acting holonomies of torsion-free affine connections. His list was complete in the part of metric connections, while the situation with holonomies of non-metric torsion-free affine connections was and remains rather unclear. One of the results discussed in this review asserts that any torsion-free holomorphic affine connecti...

  2. The Quasi—affine Maps and Fractals

    Institute of Scientific and Technical Information of China (English)

    LunhaiLONG; GangCHEN

    1997-01-01

    In this paper,we discuss the discretization of the affine maps in R2,that is ,we consider a class of maps in Z2,which are induced by affine maps and called the quasi-affine maps.We investigate the properties and the dynamical behaviour of such maps,and give a sort of construction of complicated fractals by using quasi-affine maps.

  3. Manifolds with integrable affine shape operator

    Directory of Open Access Journals (Sweden)

    Daniel A. Joaquín

    2005-05-01

    Full Text Available This work establishes the conditions for the existence of vector fields with the property that theirs covariant derivative, with respect to the affine normal connection, be the affine shape operatorS in hypersurfaces. Some results are obtained from this property and, in particular, for some kind of affine decomposable hypersurfaces we explicitely get the actual vector fields.

  4. Topological conjugacy classes of affine maps

    OpenAIRE

    2008-01-01

    A map $f: \\ff^n \\to \\ff^n$ over a field $\\ff$ is called affine if it is of the form $f(x)=Ax+b$, where the matrix $A \\in \\ff^{n\\times n}$ is called the linear part of affine map and $b \\in \\ff^n$. The affine maps over $\\ff=\\rr$ or $\\cc$ are investigated. We prove that affine maps having fixed points are topologically conjugate if and only if their linear parts are topologically conjugate. If affine maps have no fixed points and $n=1$ or 2, then they are topologically conjugate if and only if ...

  5. Using Affinity Diagrams to Evaluate Interactive Prototypes

    DEFF Research Database (Denmark)

    Lucero, Andrés

    2015-01-01

    Affinity diagramming is a technique used to externalize, make sense of, and organize large amounts of unstructured, far-ranging, and seemingly dissimilar qualitative data. HCI and interaction design practitioners have adopted and used affinity diagrams for different purposes. This paper discusses...... our particular use of affinity diagramming in prototype evaluations. We reflect on a decade’s experience using affinity diagramming across a number of projects, both in industry and academia. Our affinity diagramming process in interaction design has been tailored and consists of four stages: creating...

  6. SOIL PROPERTIES OF THE EASTERN TOPOSEQUENCE OF MOUNT KELIMUTU, FLORES ISLAND, EAST NUSA TENGGARA AND THEIR POTENTIAL FOR AGRICULTURAL USE

    Directory of Open Access Journals (Sweden)

    Hikmatullah Hikmatullah

    2016-10-01

    Full Text Available Kelimutu stratovolcano is one of the young volcanoes extensively found in Flores island. Studies on volcanic soil properties and their suitability for agricultural development in the whole island are lacking. The research was conducted to evaluate the relationship of elevation and soil properties,  and suitability for agricultural development. Five representative pedons at elevation of 550, 1,000, 1,200, 1,400, and 1,600 m above sea level (asl, respectively, were studied in the field, and 22 soil samples were analyzed in the laboratory. The results indicated that elevation significantly affected soil properties and degree of soil weathering. With decreasing elevation, sand content, amorphous material content, and phosphate retention decreased. Concomitantly, clay content, H2O-pH, exchangeable Ca and Mg, base saturation, and soil-CEC increased. A highly positive correlation was shown between P retention and NaFpH, Al, and (Al+0.5 Fe contents extracted by acid ammonium oxalate. Soil-CEC also showed significant positive correlation with clay and silt contents, organic carbon, and exchangeable Ca and Mg. Degree of weathering increased with decreasing elevation as reflected by decreasing silt/clay ratio. Soils developed from Entisols (Lithic Udorthents at 1,600 m asl, to Andisols (Typic Hapludands at 1,000-1,400 m asl, and Mollisols (Typic Hapludolls at lower elevation down to 550 m asl. Soils at 1,400-1,600 m asl are unsuitable for  agriculture. Soils at 1,000-1,200 m are moderately suitable for food crops, horticulture, and estate crops. Dominant limiting factors are steep slopes and P retention. Soils at 550 m asl are suitable for food and estate crops, and also lowland horticulture.

  7. Determinação da dissimilaridade genética entre acessos de Capsicum chinense com base em características de flores

    OpenAIRE

    2012-01-01

    As pimentas do gênero Capsicum apresentam grande importância para o mercado de condimentos e para o uso ornamental no Brasil. A estimativa da diversidade genética é importante na escolha de progenitores de programa de melhoramento genético. Este trabalho teve por objetivo verificar a eficiência de descritores multicategóricos de flores para estimar a dissimilaridade genética entre acessos de Capsicum chinense, do Banco Ativo de Germoplasma Capsicum, da Embrapa Clima Temperado. O experimento f...

  8. Efeito da desfolha de ramos sobre a indução de brotos e flores em atemóia (Anonna cherimola Mill x Anonna squamosa L.)

    OpenAIRE

    2003-01-01

    Avaliou-se o efeito do desfolhamento de ramos na produção de brotos e flores em plantas adultas de atemóia (Anonna cherimola Mill x Anonna squamosa L.) var. Gefner. O experimento foi realizado em plantio comercial no município de Maceió - AL. Foram utilizadas 24 plantas podadas com altura de 1.5 m e espaçadas de 4 x 2 m. Os ramos maduros tiveram seus ápices removidos na altura da 4ª folha, sendo depois submetidos aos seguintes tratamentos de desfolha manual: 1) desfolha total dos ramos; 2) re...

  9. PurificaÃÃo e caracterizaÃÃo de um inibidor de tripsina das flores de Cassia fistula Linn. com atividade antimicrobiana

    OpenAIRE

    Lucas Pinheiro Dias

    2012-01-01

    As plantas sintetizam proteÃnas que possuem propriedades antimicrobianas, podendo ser utilizadas em substituiÃÃo aos defensivos quÃmicos no campo e como fonte de novas drogas para o controle de infecÃÃes bacterianas em humanos. Dentre as diversas estruturas vegetais, ÃrgÃos reprodutivos como as flores parecem ser uma fonte promissora de tais molÃculas ativas contra patÃgenos, particularmente se considerado o seu relevante papel fisiolÃgico, o qual deve ser preservado. Nesse contexto, a prese...

  10. PurificaÃÃo e caracterizaÃÃo de um inibidor de tripsina das flores de Cassia fistula Linn. com atividade antimicrobiana

    OpenAIRE

    Lucas Pinheiro Dias

    2012-01-01

    As plantas sintetizam proteÃnas que possuem propriedades antimicrobianas, podendo ser utilizadas em substituiÃÃo aos defensivos quÃmicos no campo e como fonte de novas drogas para o controle de infecÃÃes bacterianas em humanos. Dentre as diversas estruturas vegetais, ÃrgÃos reprodutivos como as flores parecem ser uma fonte promissora de tais molÃculas ativas contra patÃgenos, particularmente se considerado o seu relevante papel fisiolÃgico, o qual deve ser preservado. Nesse contexto, a prese...

  11. Uso medicinal de las plantas por los otomíes del municipio de Nicolás Flores, Hidalgo, México

    OpenAIRE

    A. Sánchez-González; D. Granados-Sánchez; R. Simón-Nabor

    2008-01-01

    El conocimiento de las plantas medicinales por los otomíes (hñähñü) de Nicolás Flores, Hidalgo se ha mantenido a través de las generaciones. La influencia de la medicina alópata está restringida principalmente a la prevención de enfermedades como poliomielitis, sarampión, viruela y paludismo. La medicina tradicional es más viable ante las condiciones socioeconómicas, fisiográficas y culturales en esta región. El objetivo de este estudio fue identificar las especies de plantas que utilizan los...

  12. Presencia del elemento genético transponible dTdic1 en Dianthus caryophyllus con flores variegadas y no variegadas

    Directory of Open Access Journals (Sweden)

    Karen Rocío López Castro

    2012-08-01

    Full Text Available Título en inglés: Presence of the transposable genetic element  dTdic1 in Dianthus caryophyllus with  variegated and no variegated flowers Resumen: El objetivo de este trabajo era la búsqueda del  EGT (Elemento Genético Transponible dTdic1 que ha sido asociado con la variegación del color de las flores de clavel y su relación con dos genes que codifican para enzimas involucradas en la biosíntesis de antocianinas,  Chalcona isomerasa (CHI y Dihidroflavonol reductasa (DFR.  Su presencia y expresión se evaluó en siete genotipos con flores variegadas (líneas híbridas y en cuatro genotipos de flores no variegadas (una línea híbrida y tres cultivares comerciales.  Un alto número (indefinido de copias del elemento dTdic1 se detectó en todas las líneas variegadas y no variegadas.  En consecuencia, la sola presencia de este EGT no pudo asociarse directamente con la variegación de los pigmentos florales de flores de clavel.  Adicionalmente, dTdic1 se encontró interrumpiendo el gen CHI en cuatro genotipos variegados y uno no variegado. No se observó evidencia de inserción de dTdic1 en el gen DFR en ninguno de los genotipos. Palabras clave: Transposones; chalcona isomerasa; antocianinas Abstract: The objective of this work was to search for the EGT (Transposable Genetic Element dTdic1 that has been associated with color variegation of carnation flowers and its relationship with two genes that code for enzymes involved in the synthesis of anthocyanins, Chalcona isomerase (CHI and Dihidroflavonol reductase (DFR. Its presence and expression was evaluated in seven genotypes of variegated flowers and four no variegated flower genotypes (one hybrid line and three commercial cultivars. A high number of copies (undefined of copies of the dTdic1 element was detected in variegaated and no variegated lines. Therefore, the main presence of this EGT was not associated directly with variegation of floral pigments. Additionally, dTdic1 was

  13. Análisis de competitividad del sector de la producción y exportación de plantas y flores de orquídeas

    OpenAIRE

    Santacruz Quevedo, Genoveva

    2011-01-01

    El propósito principal de este trabajo es hacer un análisis de la competitividad en el sector de la producción y exportación de plantas y flores de orquídeas en el Ecuador. Para cumplir este propósito se realiza un estudioteórico de las cinco fuerzas de Porter y, a partir de una exploración e investigación del sector se logra un conocimiento claro sobre la realidad de las barreras contra la entrada y la salida delaindustria, datos que permitieron conocer que tan rentable y r...

  14. Diseño de un manual de procedimeintos contables para la Empresa Florícola Flores del Ecuador S.A..

    OpenAIRE

    Chillan Cusi, Miriam Elizabeth

    2005-01-01

    Toda empresa como resultado de sus operaciones genera información contable y financiera. Para que esta información sea veraz razonable y objetiva requiere de un desempeño y utilización eficiente de sus recursos humanos, materiales y financieros, sumado a esto un adecuado sistema de control interno para la detección de desviaciones. Por lo expuesto, el objetivo general de esta investigación es diseñar un manual de procedimientos contables para la empresa florícola Flores del Ecuador qu...

  15. Aspectos de la relación entre thalurania furcata colombica (aves trochilidae) y las flores en que liba, en un bosque subandino

    OpenAIRE

    Ayala R., Ana Victoria

    2012-01-01

    El mayor nivel de coadaptación ave nectarívora-flor conocido hasta el momento, se ha logrado en los Trochilidae (VAN DER PIJL & DODSON,1969; FEINSINGER et al., 1979) ; tanto, que se ha hablado de flores adaptadas a la polinización por una especie particular de colibrí, y de colibríes que dependen para su alimentación de una sola clase de flor (SNOW & SNOW, 1980).Los factores principales que afectan la selección de alimento por parte de los colibríes están relacionados con: hábitat y e...

  16. Resistance of Biomphalaria occidentalis from Varzea das Flores dam, Minas Gerais, to Schistosoma mansoni infection detected by low stringency polymerase chain reaction

    Directory of Open Access Journals (Sweden)

    Cecilia Pereira de Souza

    2001-04-01

    Full Text Available Biomphalaria occidentalis Paraense, 1981 from Varzea das Flores dam, MG, Brazil, was exposed to infection with Schistosoma mansoni. Individual infection was performed with 140 B. occidentalis and 100 B. glabrata snails using LE and SJ strains. Two groups of B. occidentalis were killed after seven day-miracidia exposure to detect S. mansoni DNA, through the low stringency polymerase chain reaction (LS-PCR, and were negative. The infection rates were 69.2% (LE strain and 96.7% (SJ strain for B. glabrata and 0% for B. occidentalis. LS-PCR enabled early resistance diagnosis.

  17. The electron affinity of phosphorus

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, P [Department of Physics, Goeteborg University, SE-412 96, Goeteborg (Sweden); Lindahl, A O [Department of Physics, Goeteborg University, SE-412 96, Goeteborg (Sweden); Alfredsson, C [Department of Physics, Goeteborg University, SE-412 96, Goeteborg (Sweden); Rogstroem, L [Department of Physics, Goeteborg University, SE-412 96, Goeteborg (Sweden); Diehl, C [Institut fuer Physik, Johannes Gutenberg-Universitaet, Mainz, D-55099 Mainz (Germany); Pegg, D J [Department of Physics, University of Tennessee, Knoxville, TN 37996 (United States); Hanstorp, D [Department of Physics, Goeteborg University, SE-412 96, Goeteborg (Sweden)

    2007-10-28

    We have measured the energies of all three fine structure components in the {sup 3}P{sub J} ground state of the negative ion of phosphorus using laser photodetachment threshold spectroscopy. The experiment yielded an electron affinity of 746.68(6) meV. The {delta}J = 2-0, 2-1 and 1-0 fine structure splittings were determined to be 32.73(7) meV, 22.48(7) meV and 10.25(3) meV, respectively. In the experiment, a mass selected beam of P{sup -} ions was merged with the output from a pulsed infrared optical parametric oscillator. The residual atoms produced in the photodetachment process were detected and used as a monitor of the photon-energy dependence of the relative cross section. The Wigner law was fitted to each of the three observed onsets of production of neutrals in order to extract the threshold energies.

  18. Beija-flores (Aves, Trochilidae e seus recursos florais em uma área urbana do Sul do Brasil Hummingbirds (Aves, Trochilidae and their flowers in an urban area of southern Brazil

    Directory of Open Access Journals (Sweden)

    Luciana Baza Mendonça

    2005-03-01

    Full Text Available A assembléia de flores visitadas por beija-flores e a partilha de recursos entre estas aves foram estudadas em uma área urbana do sul do Brasil. Vinte e duas espécies de plantas, em sua maioria exóticas e/ou não-ornitófilas, receberam visitas dos beija-flores. As espécies de beija-flores registradas apresentaram diferentes combinações de características morfológicas (massa, comprimento do bico, comprimento da asa e relação bico/asa, que refletiram no conjunto de flores exploradas e no papel comunitário desempenhado por cada espécie. De um modo geral, beija-flores com nichos tróficos mais amplos foram também os mais freqüentes na área de estudo, indicando que o ambiente urbano pode ser mais favorável às espécies generalistas.The main purpose of this study was to identify the assemblage of flowers used by hummingbirds in an urban area of southern Brazil, as well as describe the patterns of resource partitioning among the hummingbird species. Twenty two plant species were recorded, which flowers are visited by ten hummingbird species. Most of these plants are exotics and regarded as non-ornithophilous. The hummingbirds displayed different combinations of morphological features (mass, bill length, wing length and relation bill/wing, which were reflected in the sets of flowers visited and the community role played by each species. In general, hummingbirds with largest niche breadths were also the most frequent ones, indicating that urban areas could be more suitable for generalist species.

  19. Multipole solutions in metric-affine gravity

    CERN Document Server

    Socorro, J; Macías, A; Mielke, E W; Socorro, José; Lämmerzahl, Claus; Macías, Alfredo; Mielke, Eckehard W.

    1998-01-01

    Above Planck energies, the spacetime might become non--Riemannian, as it is known fron string theory and inflation. Then geometries arise in which nonmetricity and torsion appear as field strengths, side by side with curvature. By gauging the affine group, a metric affine gauge theory emerges as dynamical framework. Here, by using the harmonic map ansatz, a new class of multipole like solutions in the metric affine gravity theory (MAG) is obtained.

  20. Ordinary differential equations in affine geometry

    Directory of Open Access Journals (Sweden)

    Salvador Gigena

    1996-05-01

    Full Text Available The method of qualitative analysis is used, as applied to a class of fourth order, nonlinear ordinary differential equations, in order to classify, both locally and globally, two classes of hypersurfaces of decomposable type in affine geometry: those with constant unimodular affine mean curvature L , and those with constant Riemannian scalar curvature R. This allows to provide a large number of new examples of hypersurfaces in affine geometry.

  1. Ordinary differential equations in affine geometry

    OpenAIRE

    Salvador Gigena

    1996-01-01

    The method of qualitative analysis is used, as applied to a class of fourth order, nonlinear ordinary differential equations, in order to classify, both locally and globally, two classes of hypersurfaces of decomposable type in affine geometry: those with constant unimodular affine mean curvature L , and those with constant Riemannian scalar curvature R. This allows to provide a large number of new examples of hypersurfaces in affine geometry.

  2. Affine connections, midpoint formation, and point reflection

    DEFF Research Database (Denmark)

    Kock, Anders

    2011-01-01

    We describe some differential-geometric structures in combinatorial terms: namely affine connections and their torsion and curvature, and we show that torsion free affine connections may equivalently be presented in terms of some simpler combinatorial structure: midpoint formation, and point refl...... reflection (geodesic symmetry). The method employed is that of synthetic differential geometry, which is briefly explained.......We describe some differential-geometric structures in combinatorial terms: namely affine connections and their torsion and curvature, and we show that torsion free affine connections may equivalently be presented in terms of some simpler combinatorial structure: midpoint formation, and point...

  3. A Novel Vertex Affinity for Community Detection

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Andy [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sanders, Geoffrey [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Henson, Van [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vassilevski, Panayot [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-05

    We propose a novel vertex affinity measure in this paper. The new vertex affinity quantifies the proximity between two vertices in terms of their clustering strength and is ideal for such graph analytics applications as community detection. We also developed a framework that combines simple graph searches and resistance circuit formulas to compute the vertex affinity efficiently. We study the properties of the new affinity measure empirically in comparison to those of other popular vertex proximity metrics. Our results show that the existing metrics are ill-suited for community detection due to their lack of fundamental properties that are essential for correctly capturing inter- and intra-cluster vertex proximity.

  4. Measurement of the electron affinity of lanthanum

    Energy Technology Data Exchange (ETDEWEB)

    Covington, A.M.; Calabrese, D.; Thompson, J.S. [Department of Physics and Chemical Physics Programme, University of Nevada, Reno, NV 89557-0058 (United States); Kvale, T.J. [Department of Physics and Astronomy, University of Toledo, OH 43606-3390 (United States)

    1998-10-28

    The electron affinity of lanthanum has been measured using laser photoelectron energy spectroscopy. This is the first electron affinity measurement for lanthanum and one of the first measurements of an electron affinity of a rare-earth series element. The electron affinity of lanthanum was measured to be 0.47{+-}0.02 eV. At least one bound excited state of La{sup -} was also observed in the photoelectron spectra, and the binding energy relative to the ground state of lanthanum was measured as 0.17{+-}0.02 eV. The present experimental measurements are compared to a recent calculation. (author). Letter-to-the-editor.

  5. Floral Morphogenesis of Anemone rivularis Buch.-Ham. ex DC. var.flore-minore Maxim. (Ranunculaceae) with Special Emphasis on Androecium Developmental Sequence

    Institute of Scientific and Technical Information of China (English)

    Hong-Li CHANG; Yi REN; An-Min LU

    2005-01-01

    The floral morphogenesis and androecium developmental sequence of Anemone rivularis Buch.-Ham. ex DC. var. flore-minore Maxim. were observed under a scanning electron microscope (SEM)and by means of histological methods in order to expand our knowledge of the morphogenesis and development of the floral organs of the Ranunculaceae. The initiation of the floral elements is a centripetal spiral and the direction of the spiral is clockwise or anti-clockwise. However, the development of the androecium is highly unusual: in a longitudinal series of four stamens, the second stamen develops first from the inner to outer, then the third one, the fourth one and the first one in turn. The microsporogenesis and anther maturation follows the same developmental sequence. The tepals are different from the bracts and the stamens in both shape and size in the early developmental stage, but there is no difference between the stamens and carpels in the early developmental stage. Therefore, we established a spatio-temporal process of the floral morphogenesis of4. rivularis var.flore-minore and offer another meaning of the floral diversity patterns attributed to the level of the genus.

  6. Effect of silicon on the quality of flowers of Dendrobium nobile (OrchidaceaeEfeito do silício na qualidade de flores de Dendrobium nobile (Orchidaceae

    Directory of Open Access Journals (Sweden)

    Patricia Reiners Carvalho

    2013-09-01

    Full Text Available The orchid Dendrobium nobile Lindl is widely cultivated throughout the world as cut and potted flowers. Silicon (Si has demonstrated beneficial effects on various crops, increasing cell stiffness, giving protection to pathogens, increasing photosynthetic capacity and drought tolerance, promoting higher growth and longevity. The aim of this study was to evaluate the effect of different concentrations of silicon on Dendrobium nobile orchid flowers. Treatments were performed with magnesium silicate (SiMg at the following concentrations: 0.0, 0.16; 0.32; 0.48 and 0.64 g L-1. The foliar applications were carried out fortnightly totaling four applications two months before flowering. The variables evaluated were: longevity of flowers, number of flowers per pot and number of shoots per plant. The experimental design was completely randomized with five treatments and ten replications. The foliar applications of SiMg increased 59% flower production and shoots up to 66%, being more efficient with the increasing of concentrations. The increasing of longevity of the flowers in the dose 0.45 g L-1 was up to four days. A orquídea Dendrobium nobile Lindl é amplamente cultivada pelo mundo como flor de corte e em vasos. O silício (Si tem demonstrado efeito benéfico em diversas culturas, como por exemplo: aumentando a rigidez celular, conferindo proteção à fitopatógenos, aumento da capacidade fotossintética, tolerância à seca, promoção de maior crescimento e conservação pós-colheita. O objetivo deste trabalho foi avaliar o efeito do silício em diferentes concentrações na qualidade de flores da orquídea Dendrobium nobile. Os tratamentos foram realizados com silicato de magnésio (SiMg nas seguintes concentrações: 0,0; 0,16; 0,32; 0,48 e 0,64g L-1. As aplicações foram realizadas quinzenalmente via foliar, totalizando quatro aplicações dois meses antes do florescimento. As variáveis avaliadas foram: longevidade das flores, número de

  7. Structure of classical affine and classical affine fractional W-algebras

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Uhi Rinn, E-mail: uhrisu1@math.snu.ac.kr [Department of Mathematical Sciences, Seoul National University, GwanAkRo 1, Gwanak-Gu, Seoul 151-747 (Korea, Republic of)

    2015-01-15

    We introduce a classical BRST complex (See Definition 3.2.) and show that one can construct a classical affine W-algebra via the complex. This definition clarifies that classical affine W-algebras can be considered as quasi-classical limits of quantum affine W-algebras. We also give a definition of a classical affine fractional W-algebra as a Poisson vertex algebra. As in the classical affine case, a classical affine fractional W-algebra has two compatible λ-brackets and is isomorphic to an algebra of differential polynomials as a differential algebra. When a classical affine fractional W-algebra is associated to a minimal nilpotent, we describe explicit forms of free generators and compute λ-brackets between them. Provided some assumptions on a classical affine fractional W-algebra, we find an infinite sequence of integrable systems related to the algebra, using the generalized Drinfel’d and Sokolov reduction.

  8. Scaling analysis of affinity propagation.

    Science.gov (United States)

    Furtlehner, Cyril; Sebag, Michèle; Zhang, Xiangliang

    2010-06-01

    We analyze and exploit some scaling properties of the affinity propagation (AP) clustering algorithm proposed by Frey and Dueck [Science 315, 972 (2007)]. Following a divide and conquer strategy we setup an exact renormalization-based approach to address the question of clustering consistency, in particular, how many cluster are present in a given data set. We first observe that the divide and conquer strategy, used on a large data set hierarchically reduces the complexity O(N2) to O(N((h+2)/(h+1))) , for a data set of size N and a depth h of the hierarchical strategy. For a data set embedded in a d -dimensional space, we show that this is obtained without notably damaging the precision except in dimension d=2 . In fact, for d larger than 2 the relative loss in precision scales such as N((2-d)/(h+1)d). Finally, under some conditions we observe that there is a value s* of the penalty coefficient, a free parameter used to fix the number of clusters, which separates a fragmentation phase (for ss*) of the underlying hidden cluster structure. At this precise point holds a self-similarity property which can be exploited by the hierarchical strategy to actually locate its position, as a result of an exact decimation procedure. From this observation, a strategy based on AP can be defined to find out how many clusters are present in a given data set.

  9. Meet Rudy Flores.

    Science.gov (United States)

    Power, Jane

    1980-01-01

    The problems and satisfactions of teaching deaf children are discussed in this interview with a teacher of the deaf. Uses of Ameslon and signed English, talking, and valuable teaching approaches are offered. (JD)

  10. Phosphopeptide enrichment by immobilized metal affinity chromatography

    DEFF Research Database (Denmark)

    Thingholm, Tine E.; Larsen, Martin R.

    2016-01-01

    Immobilized metal affinity chromatography (IMAC) has been the method of choice for phosphopeptide enrichment prior to mass spectrometric analysis for many years and it is still used extensively in many laboratories. Using the affinity of negatively charged phosphate groups towards positively...

  11. Dyes with high affinity for polylactide

    Institute of Scientific and Technical Information of China (English)

    Liang He; Shu Fen Zhang; Bing Tao Tang; Li Li Wang; Jin Zong Yang

    2007-01-01

    Attempts were made to develop dyes with high affinity for polylactide as an alternative to the existent commercial disperse dyes.The dyes synthesized according to the affinity concept of dye to polylactide exhibited excellent dyeing properties on polylactide compared with the commercial disperse dyes.

  12. Porosity of Self-affine Sets

    Institute of Scientific and Technical Information of China (English)

    Lifeng XI

    2008-01-01

    In this paper,it is proved that any self-affine set satisfying the strong separation condition is uniformly porous.The author constructs a self-affine set which is not porous,although the open set condition holds.Besides,the author also gives a C1 iterated function system such that its invariant set is not porous.

  13. On affine non-negative matrix factorization

    DEFF Research Database (Denmark)

    Laurberg, Hans; Hansen, Lars Kai

    2007-01-01

    We generalize the non-negative matrix factorization (NMF) generative model to incorporate an explicit offset. Multiplicative estimation algorithms are provided for the resulting sparse affine NMF model. We show that the affine model has improved uniqueness properties and leads to more accurate...

  14. Affine processes on positive semidefinite matrices

    CERN Document Server

    Cuchiero, Christa; Mayerhofer, Eberhard; Teichmann, Josef

    2009-01-01

    This paper provides the mathematical foundation for stochastically continuous affine processes on the cone of positive semidefinite symmetric matrices. These matrix-valued affine processes have arisen from a large and growing range of useful applications in finance, including multi-asset option pricing with stochastic volatility and correlation structures, and fixed-income models with stochastically correlated risk factors and default intensities.

  15. Improving image segmentation by learning region affinities

    Energy Technology Data Exchange (ETDEWEB)

    Prasad, Lakshman [Los Alamos National Laboratory; Yang, Xingwei [TEMPLE UNIV.; Latecki, Longin J [TEMPLE UNIV.

    2010-11-03

    We utilize the context information of other regions in hierarchical image segmentation to learn new regions affinities. It is well known that a single choice of quantization of an image space is highly unlikely to be a common optimal quantization level for all categories. Each level of quantization has its own benefits. Therefore, we utilize the hierarchical information among different quantizations as well as spatial proximity of their regions. The proposed affinity learning takes into account higher order relations among image regions, both local and long range relations, making it robust to instabilities and errors of the original, pairwise region affinities. Once the learnt affinities are obtained, we use a standard image segmentation algorithm to get the final segmentation. Moreover, the learnt affinities can be naturally unutilized in interactive segmentation. Experimental results on Berkeley Segmentation Dataset and MSRC Object Recognition Dataset are comparable and in some aspects better than the state-of-art methods.

  16. Reflectable bases for affine reflection systems

    CERN Document Server

    Azam, Saeid; Yousofzadeh, Malihe

    2011-01-01

    The notion of a "root base" together with its geometry plays a crucial role in the theory of finite and affine Lie theory. However, it is known that such a notion does not exist for the recent generalizations of finite and affine root systems such as extended affine root systems and affine reflection systems. As an alternative, we introduce the notion of a "reflectable base", a minimal subset $\\Pi$ of roots such that the non-isotropic part of the root system can be recovered by reflecting roots of $\\Pi$ relative to the hyperplanes determined by $\\Pi$. We give a full characterization of reflectable bases for tame irreducible affine reflection systems of reduced types, excluding types $E_{6,7,8}$. As a byproduct of our results, we show that if the root system under consideration is locally finite then any reflectable base is an integral base.

  17. The Homo Floresiensis Cranium (LB1): Size, Scaling, and Early Homo Affinities

    National Research Council Canada - National Science Library

    Adam D. Gordon; Lisa Nevell; Bernard Wood

    2008-01-01

    The skeletal remains of a diminutive small-brained hominin found in Late Pleistocene cave deposits on the island of Flores, Indonesia were assigned to a new species, Homo floresiensis [Brown P, et al. (2004...

  18. Non-Zenoness of piecewise affine dynamical systems and affine complementarity systems with inputs

    Institute of Scientific and Technical Information of China (English)

    Le Quang THUAN

    2014-01-01

    In the context of continuous piecewise affine dynamical systems and affine complementarity systems with inputs, we study the existence of Zeno behavior, i.e., infinite number of mode transitions in a finite-length time interval, in this paper. The main result reveals that continuous piecewise affine dynamical systems with piecewise real-analytic inputs do not exhibit Zeno behavior. Applied the achieved result to affine complementarity systems with inputs, we also obtained a similar conclusion. A direct benefit of the main result is that one can apply smooth ordinary differential equations theory in a local manner for the analysis of continuous piecewise affine dynamical systems with inputs.

  19. Optimización del tratamiento de aguas residuales de cultivos de flores usando humedales construidos de flujo subsuperficial horizontal

    Directory of Open Access Journals (Sweden)

    Mónica L. Jaramillo-Gallego

    2016-02-01

    Full Text Available Resumen Objetivo: optimizar un sistema de tratamiento de aguas residuales de cultivos de flores, con el fin de mejorar la eficiencia en la remoción de los contaminantes, usando humedales construidos de flujo subsuperficial-horizontal. Metodología: se realizó un estudio de tipo exploratorio experimental en dos etapas, en la primera se efectuó el acondicionamiento fisicoquímico y biológico del sistema de tratamiento, en la segunda, se llevó a cabo el seguimiento de la remoción de los contaminantes durante nueve meses, para lo cual se monitoreó la demanda química de oxígeno, demanda biológica de oxígeno, sólidos totales, sólidos suspendidos totales, pH y oxígeno disuelto. Resultados: Se logró mejorar la eficiencia del sistema de tratamiento en 7,1% para la Demanda biológica de oxígeno, 4,1% Demanda química de oxígeno, 56,9% sólidos totales y 117,2% solidos suspendidos totales. Conclusión: La concentración de DQO disminuyó con el tratamiento primario (Precipitación y oxidación química y favoreció la eficiencia del sistema de tratamiento secundario, dado que las aguas a tratar tenían valores muy altos de DQO que pueden saturar los humedales con contaminantes persistentes. Se podrían obtener mayores eficiencias, si se logra mejorar el sistema de tratamiento primario. Abstract Objective: to optimize the wastewater treatment system of flower crops in order to improve pollutant removal efficiency, using a horizontal subsurface flow constructed wetland. Methodology: An exploratory experimental study was conducted in two stages; in the first stage the treatment system was conditioned physically, chemically and biologically. In the second stage pollutant removal was monitored for nine months. To achieve this, chemical oxygen demand, biological oxygen demand, total solids, total suspended solids, pH and dissolved oxygen were monitored. Results: It was possible to improve the efficiency of the treatment system in 7.1% for

  20. Produção de flores cortadas no estado de Minas Gerais Production of cut flowers in the state o Minas Gerais

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Correa Landgraf

    2009-02-01

    Full Text Available As flores de corte são importantes produtos da floricultura brasileira, as características da produção mineira são, no entanto, desconhecidas. Objetivou-se realizar um estudo da produção de flores de corte no estado de Minas Gerais, aplicou-se um questionário aos produtores do Estado , no período de 2003 a 2005. As visitas foram feitas in loco e os produtores foram identificados por meio de visitas nas áreas produtivas e os questionários foram respondidos por eles próprios. Analisando-se as respostas contidas nos questionários, identificou-se que a produção de flores de corte no estado de Minas Gerais é uma atividade realizada por 188 produtores, numa área plantada de aproximadamente 290,6836 ha As principais espécies cultivadas no Estado são: rosa (151,5710, sempre-vivas (57,26 ha, copo-de-leite (16,0255 ha, cravo (12,6290 ha e helicônia (11,7600 ha. A produção é vendida para o todo o Brasil e também exportada para países da Europa, Ásia e América do Norte. Os principais produtos exportados são: rosas de corte, orquídeas de corte e sempre-vivas.Cut flowers are important products of Brazilian floriculture. The characteristics of Minas Gerais production are, nevertheless, unknown. So, with the purpose of performing a study of the cut flower production in the state of Minas Gerais, a questionnaire was applied to flower growers of Minas Gerais state, in the period of 2003 to 2005. The visits were paid in loco and the growers were identified by means of visits to the flower-growing areas and the questionnaires were answered by them. By analyzing the answers contained in the questionnaires, it was identified that the cut flower production in the state of Minas Gerais is a business accomplished by 188 growers in a planted area of about 290.6836 ha. The main species grown in the state are: rose (151.5710 ha, sempre-vivas (57.26 ha, cala lilly flowers (16.0255 ha, carnation (12.6290 ha and heliconia (11.7600 ha. The

  1. The Cutting Edge of Affinity Electrophoresis Technology

    Directory of Open Access Journals (Sweden)

    Eiji Kinoshita

    2015-03-01

    Full Text Available Affinity electrophoresis is an important technique that is widely used to separate and analyze biomolecules in the fields of biology and medicine. Both quantitative and qualitative information can be gained through affinity electrophoresis. Affinity electrophoresis can be applied through a variety of strategies, such as mobility shift electrophoresis, charge shift electrophoresis or capillary affinity electrophoresis. These strategies are based on changes in the electrophoretic patterns of biological macromolecules that result from interactions or complex-formation processes that induce changes in the size or total charge of the molecules. Nucleic acid fragments can be characterized through their affinity to other molecules, for example transcriptional factor proteins. Hydrophobic membrane proteins can be identified by means of a shift in the mobility induced by a charged detergent. The various strategies have also been used in the estimation of association/disassociation constants. Some of these strategies have similarities to affinity chromatography, in that they use a probe or ligand immobilized on a supported matrix for electrophoresis. Such methods have recently contributed to profiling of major posttranslational modifications of proteins, such as glycosylation or phosphorylation. Here, we describe advances in analytical techniques involving affinity electrophoresis that have appeared during the last five years.

  2. The Cutting Edge of Affinity Electrophoresis Technology

    Science.gov (United States)

    Kinoshita, Eiji; Kinoshita-Kikuta, Emiko; Koike, Tohru

    2015-01-01

    Affinity electrophoresis is an important technique that is widely used to separate and analyze biomolecules in the fields of biology and medicine. Both quantitative and qualitative information can be gained through affinity electrophoresis. Affinity electrophoresis can be applied through a variety of strategies, such as mobility shift electrophoresis, charge shift electrophoresis or capillary affinity electrophoresis. These strategies are based on changes in the electrophoretic patterns of biological macromolecules that result from interactions or complex-formation processes that induce changes in the size or total charge of the molecules. Nucleic acid fragments can be characterized through their affinity to other molecules, for example transcriptional factor proteins. Hydrophobic membrane proteins can be identified by means of a shift in the mobility induced by a charged detergent. The various strategies have also been used in the estimation of association/disassociation constants. Some of these strategies have similarities to affinity chromatography, in that they use a probe or ligand immobilized on a supported matrix for electrophoresis. Such methods have recently contributed to profiling of major posttranslational modifications of proteins, such as glycosylation or phosphorylation. Here, we describe advances in analytical techniques involving affinity electrophoresis that have appeared during the last five years.

  3. Affinization of category O for quantum groups

    CERN Document Server

    Young, C A S

    2012-01-01

    Let g be a simple Lie algebra. We consider the category O-hat of those modules over the affine quantum group Uq(g-hat) whose Uq(g)-weights have finite multiplicity and lie in a finite union of cones generated by negative roots. We show that many properties of the category of the finite-dimensional representations naturally extend to the category O-hat. In particular, we develop the theory of q-characters and define the minimal affinizations of parabolic Verma modules. In types ABCFG we classify these minimal affinizations and conjecture a Weyl denominator type formula for their characters.

  4. Corner Transfer Matrices and Quantum Affine Algebras

    CERN Document Server

    Foda, O E; Foda, Omar; Miwa, Tetsuji

    1992-01-01

    Let H be the corner-transfer-matrix Hamiltonian for the six-vertex model in the anti-ferroelectric regime. It acts on the infinite tensor product W = V . V . V ....., where is the 2-dimensional irreducible representation of the quantum affine sl(2). We observe that H is the derivation of quantum affine sl(2), and conjecture that the eigenvectors of H form the level-1 vacuum representation of quantum affine sl(2). We report on checks in support of our conjecture.

  5. Cultivo de flores com o uso de água residuária e suplementação mineral Flower cultivation using wasterwater and mineral supplementation

    Directory of Open Access Journals (Sweden)

    Salomão de S. Medeiros

    2010-12-01

    Full Text Available Este trabalho visa a avaliar o efeito da adubação nitrogenada e potássica na produção de gérbera (Gerbera jamesonni, tipo comercial Rambo, utilizando-se de dois tipos de águas (residuária de origem urbana e de abastecimento para irrigação. O experimento foi realizado em casa de vegetação, na Universidade Federal de Campina Grande, de outubro de 2006 a janeiro de 2007, abrangendo um ciclo completo de produção. O delineamento experimental utilizado foi o de blocos casualizados, com três repetições, e os tratamentos foram dispostos em esquema fatorial 3 x 4 x 2, em que os fatores estudados foram: níveis crescente de nitrogênio (N1 = 100; N2 = 200 e N3 = 300 mg L-1 e potássio (K1 = 100; K2 = 200; K3 = 300 e K4 = 400 mg L-1 adicionados a uma solução contendo fósforo (P1 = 50 mg L-1; com a utilização de dois tipos de água (A1 = abastecimento, e A2 = residuária de origem urbana. As variáveis monitoradas foram: número de botões florais emitidos e intervalo de emissão; número de flores colhidas e intervalo entre colheitas; diâmetro das flores e comprimento das hastes. O incremento de nitrogênio, apesar de propiciar incremento no número de botões e reduzir o tempo de emissão de botões, ocasionou efeito negativo quanto à qualidade das flores produzidas; já o incremento de potássio foi benéfico. O uso de água residuária possibilitou melhoria significativa na produtividade e redução no tempo de colheita sem efeito significativo na qualidade das flores produzidas. Não foram observadas interações significativas entre os fatores estudados.This study aimed to evaluate the effect of nitrogen and potassium in production of Gerbera (Gerbera jamesonni, commercial type Rambo, using two types of water (residual of urban origin and muncipality supply water for irrigation. The experiment was conducted in a greenhouse, at the Federal University of Campina Grande, from October 2006 to January 2007, covering a complete cycle

  6. A produÃÃo de flores no estado do Cearà em BaturitÃ, redenÃÃo e SÃo Benedito

    OpenAIRE

    Luzianny Borges Rocha

    2006-01-01

    Esta pesquisa analisa, em especial, o processo da produÃÃo de flores nos municÃpios de BaturitÃ, RedenÃÃo e SÃo Benedito, no Estado do CearÃ. A escolha destes, como objeto de anÃlise do ponto de vista geogrÃfico, deve-se ao destaque no espaÃo cearense, no que se refere Ãs metamorfoses na estrutura produtiva e espacial, que sÃo reflexos das polÃticas pÃblicas e privadas que criam as condiÃÃes favorÃveis para a reproduÃÃo ampliada do capital. Diante disso, questiona-se a respeito da expansÃo da...

  7. A produÃÃo de flores no estado do Cearà em BaturitÃ, redenÃÃo e SÃo Benedito

    OpenAIRE

    Luzianny Borges Rocha

    2006-01-01

    Esta pesquisa analisa, em especial, o processo da produÃÃo de flores nos municÃpios de BaturitÃ, RedenÃÃo e SÃo Benedito, no Estado do CearÃ. A escolha destes, como objeto de anÃlise do ponto de vista geogrÃfico, deve-se ao destaque no espaÃo cearense, no que se refere Ãs metamorfoses na estrutura produtiva e espacial, que sÃo reflexos das polÃticas pÃblicas e privadas que criam as condiÃÃes favorÃveis para a reproduÃÃo ampliada do capital. Diante disso, questiona-se a respeito da expansÃo da...

  8. Intérêt de l'étude de la flore des diatomées du lieu de submersion dans le diagnostic de noyade

    Directory of Open Access Journals (Sweden)

    LUDES B.

    1996-04-01

    Full Text Available La recherche de diatomées dans les tissus de la victime pour contribuer au diagnostic de noyade doit être accompagnée de l'analyse d'un échantillon d'eau prélevé sur les lieux de précipitation ou de découverte du corps. Cet échantillon permet d'établir un inventaire représentatif de la flore du lieu de découverte ou de submersion, et d'effectuer les comparaisons avec les taxons trouvés dans les tissus. De plus, la détermination de taxons dominants dans l'échantillon d'eau peut avoir une valeur indicative du lieu de découverte.

  9. Variations in Organic Matter Burial and Composition in Sediments from the Indian Ocean Continental Margin Off SW Indonesia (Sumatra - Java - Flores) Since the Last Glacial Maximum

    Science.gov (United States)

    Jennerjahn, T. C.; Gesierich, K.; Schefuß, E.; Mohtadi, M.

    2014-12-01

    Global climate change is a mosaic of regional changes to a large extent determined by region-specific feedbacks between climate and ecosystems. At present the ocean is forming a major sink in the global carbon cycle. Organic matter (OM) storage in sediments displays large regional variations and varied over time during the Quaternary. Upwelling regions are sites of high primary productivity and major depocenters of organic carbon (OC), the least understood of which is the Indian Ocean upwelling off Indonesia. In order to reconstruct the burial and composition of OM during the Late Quaternary, we analyzed five sediment cores from the Indian Ocean continental margin off the Indonesian islands Sumatra to Flores spanning the last 20,000 years (20 kyr). Sediments were analyzed for bulk composition, stable carbon and nitrogen isotopes of OM, amino acids and hexosamines and terrestrial plant wax n-alkanes and their stable carbon isotope composition. Sedimentation rates hardly varied over time in the western part of the transect. They were slightly lower in the East during the Last Glacial Maximum (LGM) and deglaciation, but increased strongly during the Holocene. The amount and composition of OM was similar along the transect with maximum values during the deglaciation and the late Holocene. High biogenic opal covarying with OM content indicates upwelling-induced primary productivity dominated by diatoms to be a major control of OM burial in sediments in the East during the past 20 kyr. The content of labile OM was low throughout the transect during the LGM and increased during the late Holocene. The increase was stronger and the OM less degraded in the East than in the West indicating that continental margin sediments off Java and Flores were the major depocenter of OC burial along the Indian Ocean margin off SW Indonesia. Temporal variations probably resulted from changes in upwelling intensity and terrestrial inputs driven by variations in monsoon strength.

  10. Estado peronista y cooperativismo eléctrico: El caso de la Cooperativa Eléctrica de Las Flores entre 1946 y 1951

    Directory of Open Access Journals (Sweden)

    Luis Rodrigo La Scaleia

    2006-01-01

    Full Text Available El rubro de la electricidad fue uno de los sectores más dinámicos para la transformación económica que experimentó la Argentina en la década del 40. Al mismo tiempo fue una de las ramas en las que se desarrolló más fuertemente el cooperativismo, que jugó un papel esencial en la provisión de energía eléctrica, fuera de los grandes centros urbanos. En este trabajo se estudia el desenvolvimiento de la Cooperativa Eléctrica de Las Flores destinada al suministro de energía del partido homónimo, en el interior de la Provincia de Buenos Aires entre 1946 y 1951. Finalmente el trabajo analiza la política energética primero en la Provincia de Buenos Aires durante al Gobierno de Domingo Mercante y segundo en el ámbito nacional, durante la primera presidencia de Juan Perón.The sector of electricity was one of the more dynamics for the economic transformation, which Argentine had experimented in the 40ies. At the same time, it was a brnch in which the cooperativism was strongly developed, being extremely important for the provision of electric energy, out of the huge urben centres. In this work it is studied the development of the electric cooperative of Las Flores destinated to the suministry of energy of the similar district, in the inner of the Buenos Aires Province between 1946 and 1951. Finally the study analyses the energetic politic, firstly in the Province of Buenos Aires during Domingo Mercante's government and secondly in the national circuit, during Juan Perón's presidency.

  11. Fatty acid and drug binding to a low-affinity component of human serum albumin, purified by affinity chromatography

    DEFF Research Database (Denmark)

    Vorum, H; Pedersen, A O; Honoré, B

    1992-01-01

    of two albumin components about 40% of the albumin having high affinity and about 60% having low affinity. By affinity chromatography we succeeded in purifying the low-affinity component from the mixture. The high-affinity component, however, could not be isolated. We further analyzed the fatty acid...

  12. Protein electrophoretic markers in Israel: compilation of data and genetic affinities.

    Science.gov (United States)

    Zoossmann-Diskin, A; Joel, A; Liron, M; Kerem, B; Shohat, M; Peleg, L

    2002-01-01

    A considerable body of data has been accumulated since the 1960s on protein electrophoretic markers in the Jewish populations of Israel. However, in some Jewish communities and for some markers insufficient information has been available. In addition, studies that tried to explore the genetic affinities of various Jewish populations mainly employed antigenic markers and frequently used a small and unrepresentative number of non-Jewish populations as comparisons. The primary objectives of the present study were to create a comprehensive database for protein electrophoretic markers in Israel and thereby to explore the genetic affinities of different Jewish populations. Published information on red cell enzyme and serum protein polymorphisms in Israeli Jewish populations was combined with new data obtained by protein electrophoresis and DNA PCR (polymerase chain reaction) methods to create the database. The genetic affinities were investigated by two methods. Ten Jewish populations were classified in a discriminant analysis based on nine markers and 65 non-Jewish populations. The same markers and populations were also used in a genetic distance analysis. The database contains new information on 15 protein electrophoretic markers in 14 Israeli populations, including three Jewish populations from Turkey, Tunisia and the Caucasus region, for which no or only scarce data were previously available. The discriminant analysis resulted in only two Jewish populations, from Iraq and Yemen, being classified within the Middle Eastern group. According to their genetic distances, no particular genetic similarity was observed between the various Jewish study populations. In contrast to the conclusions of several previous studies, there was no evidence for close genetic affinities among the Jewish populations or for a Middle Eastern origin for most of them. Since the study is the first to use only the more reliable protein electrophoretic markers, and an appropriately comprehensive

  13. Scaling laws in phytoplankton nutrient uptake affinity

    DEFF Research Database (Denmark)

    Lindemann, Christian; Fiksen, Øyvind; Andersen, Ken Haste

    2016-01-01

    instantaneously. Here we provide empirical evidence that the perfect sink strategy is not common in phytoplankton. Although small cells are indeed favored by a large surface to volume ratio, we show that they are punished by higher relative investment cost in order to fully benefit from the larger surface......Nutrient uptake affinity affects the competitive ability of microbial organisms at low nutrient concentrations. From the theory of diffusion limitation it follows that uptake affinity scales linearly with the cell radius. This is in conflict with some observations suggesting that uptake affinity...... to volume ratio. We show that there are two reasons for this. First, because the small cells need a higher transporter density in order to maximize their affinity, and second because the relative cost of a transporter is higher for a small than for a large cell. We suggest that this might explain why...

  14. Estimating affinities of calcium ions to proteins

    Directory of Open Access Journals (Sweden)

    Stefan Franke

    2010-03-01

    Full Text Available Stefan Franke, Julia Herfurth, Daniel HoffmannDepartment of Bioinformatics/Centre for Medical Biotechnology, University of Duisburg-Essen, Essen, GermanyAbstract: Ca2+-ions have a range of affinities to different proteins, depending on the various functions of these proteins. This makes the determination of Ca2+-protein affinities an interesting subject for functional studies. We have investigated the performance of two methods – Fold-X and AutoDock vina – in the prediction of Ca2+-protein affinities. Both methods, although based on different energy functions, showed virtually the same correlation with experimental affinities. Guided by insight from experiment, we further derived a simple linear model based on thesolvent accessible surface of Ca2+ that had practically the same performance in terms of absolute errors as the more complex docking methods.Keywords: metal ions, binding, free energy, crystal structure, solvent accessible surface

  15. Estimating affinities of calcium ions to proteins

    Science.gov (United States)

    Franke, Stefan; Herfurth, Julia; Hoffmann, Daniel

    2010-01-01

    Ca2+-ions have a range of affinities to different proteins, depending on the various functions of these proteins. This makes the determination of Ca2+-protein affinities an interesting subject for functional studies. We have investigated the performance of two methods – Fold-X and AutoDock vina – in the prediction of Ca2+-protein affinities. Both methods, although based on different energy functions, showed virtually the same correlation with experimental affinities. Guided by insight from experiment, we further derived a simple linear model based on the solvent accessible surface of Ca2+ that had practically the same performance in terms of absolute errors as the more complex docking methods. PMID:21918621

  16. Protein purification using PDZ affinity chromatography.

    Science.gov (United States)

    Walkup, Ward G; Kennedy, Mary B

    2015-04-01

    PDZ domains function in nature as protein-binding domains within scaffold and membrane-associated proteins. They comprise approximately 90 residues and undergo specific, high-affinity interactions with complementary C-terminal peptide sequences, other PDZ domains, and/or phospholipids. We have previously shown that the specific, strong interactions of PDZ domains with their ligands make them well suited for use in affinity chromatography. This unit provides protocols for the PDZ affinity chromatography procedure that are applicable for the purification of proteins that contain PDZ domains or PDZ domain-binding ligands, either naturally or introduced by genetic engineering. We detail the preparation of affinity resins composed of PDZ domains or PDZ domain peptide ligands coupled to solid supports. These resins can be used to purify proteins containing endogenous or genetically introduced PDZ domains or ligands, eluting the proteins with free PDZ domain peptide ligands.

  17. Fan affinity laws from a collision model

    CERN Document Server

    Bhattacharjee, Shayak

    2012-01-01

    The performance of a fan is usually estimated from hydrodynamical considerations. The calculations are long and involved and the results are expressed in terms of three affinity laws. In this work we use kinetic theory to attack this problem. A hard sphere collision model is used, and subsequently a correction to account for the flow behaviour of air is incorporated. Our calculations prove the affinity laws and provide numerical estimates of the air delivery, thrust and drag on a rotating fan.

  18. APPROXIMATE OUTPUT REGULATION FOR AFFINE NONLINEAR SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Yali DONG; Daizhan CHENG; Huashu QIN

    2003-01-01

    Output regulation for affine nonlinear systems driven by an exogenous signal is investigated in this paper. In the absence of the standard exosystem hypothesis, we assume availability of the instantaneous values of the exogenous signal and its first time-derivative for use in the control law.For affine nonlinear systems, the necessary and sufficient conditions of the solvability of approximate output regulation problem are obtained. The precise form of the control law is presented under some suitable assumptions.

  19. Applications of new affine invariant for polytopes

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    To study the Schneider's projection problem,Lutwak,Yang and Zhang recently introduced a new .affine invariant functional U(P) for convex polytopes in Rn.In the paper,we obtain the analytic expression of the affine-invariant U(P) defined on a specific subclass of origin-symmetric convex polytopes in Rn and give an application of U(P) to the Lp-Minkowski problem.

  20. A new series of emodin derivatives with bone affinity

    Institute of Scientific and Technical Information of China (English)

    Hong Chen; Ying Wang; Ling Leng; Mao Sheng Cheng; Peng Fei Yu; Jing Ze Zhang

    2007-01-01

    A new series of bone affinity compounds were synthesized by linking emodin with 5-fluorouracil derivatives. Their bone affinities were established by hydroxyapative (HA) affinity experiment in vitro, and their cytostatic effects were shown by the MTT assay.

  1. Synthesis of a New Series of Bone Affinity Compounds

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A new series of bone affinity compounds were synthesized by linking chrysophanol with 5-fluorouracil derivatives. Their bone affinity was established by hydroxyapafive (HA)affinity experiment in vitro, and their cytostatic effects were shown by the MTT assay.

  2. Short-term desensitization of muscarinic cholinergic receptors in mouse neuroblastoma cells: selective loss of agonist low-affinity and pirenzepine high-affinity binding sites

    Energy Technology Data Exchange (ETDEWEB)

    Cioffi, C.L.; el-Fakahany, E.E.

    1986-09-01

    The effects of brief incubation with carbamylcholine on subsequent binding of (/sup 3/H)N-methylscopolamine were investigated in mouse neuroblastoma cells (clone N1E-115). This treatment demonstrated that the muscarinic receptors in this neuronal clone can be divided into two types; one which is readily susceptible to regulation by receptor agonists, whereas the other is resistant in this regard. In control cells, both pirenzepine and carbamylcholine interacted with high- and low-affinity subsets of muscarinic receptors. Computer-assisted analysis of the competition between pirenzepine and carbamylcholine with (/sup 3/H)N-methylscopolamine showed that the receptor sites remaining upon desensitization are composed mainly of pirenzepine low-affinity and agonist high-affinity binding sites. Furthermore, there was an excellent correlation between the ability of various muscarinic receptor agonists to induce a decrease in consequent (/sup 3/H)N-methylscopolamine binding and their efficacy in stimulating cyclic GMP synthesis in these cells. Thus, only the agonists that are known to recognize the receptor's low-affinity conformation in order to elicit increases in cyclic GMP levels were capable of diminishing ligand binding. Taken together, our present results suggest that the receptor population that is sensitive to regulation by agonists includes both the pirenzepine high-affinity and the agonist low-affinity receptor binding states. In addition, the sensitivity of these receptor subsets to rapid regulation by agonists further implicates their involvement in desensitization of muscarinic receptor-mediated cyclic GMP formation.

  3. The connection between metal ion affinity and ligand affinity in integrin I domains

    DEFF Research Database (Denmark)

    Vorup-Jensen, Thomas; Waldron, TT; Astrof, N;

    2007-01-01

    Integrins are cell-surface heterodimeric proteins that mediate cell-cell, cell-matrix, and cell-pathogen interactions. Half of the known integrin alpha subunits contain inserted domains (I domains) that coordinate ligand through a metal ion. Although the importance of conformational changes within...... isolated I domains in regulating ligand binding has been reported, the relationship between metal ion binding affinity and ligand binding affinity has not been elucidated. Metal and ligand binding by several I domain mutants that are stabilized in different conformations are investigated using isothermal...... titration calorimetry and surface plasmon resonance studies. This work suggests an inverse relationship between metal ion affinity and ligand binding affinity (i.e. constructs with a high affinity for ligand exhibit a low affinity for metal). This trend is discussed in the context of structural studies...

  4. Dinâmica floral e abortamento de flores em híbridos de canola e mostarda castanha Floral dynamics and flower abortion in hybrids of canola and Indian mustard

    Directory of Open Access Journals (Sweden)

    Rafael Battisti

    2013-02-01

    Full Text Available O objetivo deste trabalho foi avaliar a dinâmica floral e determinar o índice de abortamento de flores de híbridos de canola (Brassica napus e de mostarda castanha (Brassica juncea, bem como determinar suas relações com as condições meteorológicas do Sul do Brasil. Durante a floração, dez híbridos de canola e dois de mostarda foram avaliados a cada três dias quanto ao número de flores abertas, de síliquas e de flores abortadas. O número acumulado e relativo de flores foi usado para avaliação da dinâmica floral. A relação desses números com a soma térmica acumulada durante a floração foi determinada por meio de modelo logístico. A partir dos coeficientes desse modelo, identificaram-se grupos de genótipos com diferentes taxas de emissão de flores. O abortamento de flores entre híbridos variou de 10,53 a 45,96% e correlacionou-se com a temperatura e a demanda evaporativa da atmosfera. Genótipos com maiores tempos térmicos entre o período de máxima emissão de flores e o final da floração geralmente apresentam maiores percentagens de abortamento de flores. O ajuste dos dados de emissão de flores aos de soma térmica do período da floração, por meio de modelo logístico, permite simular a dinâmica floral de híbridos de canola e mostarda castanha.The objective of this work was to evaluate the floral dynamics and to determine the index of flower abortion in canola (Brassica napus and Indian mustard (Brassica juncea hybrids, as well as to determine their relation with meteorological conditions of southern Brazil. During flowering, ten hybrids of canola and two of Indian mustard were evaluated every three days as to the number of open flowers, pods, and aborted flowers. The cumulative and the relative number of flowers were used to evaluate floral dynamics. The relation of these numbers with the accumulated thermal sum during flowering was determined with a logistic model. Groups of genotypes with different

  5. Patrimony and production in the rural environments of Buenos Aires. San José de Flores, 1800-1875 Patrimonio y producción en los entornos rurales de Buenos Aires. San José de Flores, 1800-1875

    Directory of Open Access Journals (Sweden)

    Valeria Ciliberto

    2007-01-01

    Full Text Available In the present article, I aim to reconstruct the productive characteristics of the crop and grain farms in San Jose de Flores district through the analysis of the information provided by wills and testaments and postmortem inventories. In addition, I approach the study of the investment schemes of the proprietors and/or tenants of these farms in order to outline a socioeconomic and political profile, focusing on those tenants that have obtained the legal property of the lands.En el presente artículo reconstruimos a partir de la información proporcionada por testamentos e inventarios post mortem las características productivas de los establecimientos frutihortícolas y cerealeros del partido de San José de Flores. Abordamos, además, el estudio de los esquemas de inversión de los propietarios y/o arrendatarios de estas unidades esbozando su perfil socioeconómico y político, deteniéndonos especialmente en aquellos que han accedido a la propiedad legal de los terrenos.

  6. Shark Attack: high affinity binding proteins derived from shark vNAR domains by stepwise in vitro affinity maturation.

    Science.gov (United States)

    Zielonka, Stefan; Weber, Niklas; Becker, Stefan; Doerner, Achim; Christmann, Andreas; Christmann, Christine; Uth, Christina; Fritz, Janine; Schäfer, Elena; Steinmann, Björn; Empting, Martin; Ockelmann, Pia; Lierz, Michael; Kolmar, Harald

    2014-12-10

    A novel method for stepwise in vitro affinity maturation of antigen-specific shark vNAR domains is described that exclusively relies on semi-synthetic repertoires derived from non-immunized sharks. Target-specific molecules were selected from a CDR3-randomized bamboo shark (Chiloscyllium plagiosum) vNAR library using yeast surface display as platform technology. Various antigen-binding vNAR domains were easily isolated by screening against several therapeutically relevant antigens, including the epithelial cell adhesion molecule (EpCAM), the Ephrin type-A receptor 2 (EphA2), and the human serine protease HTRA1. Affinity maturation was demonstrated for EpCAM and HTRA1 by diversifying CDR1 of target-enriched populations which allowed for the rapid selection of nanomolar binders. EpCAM-specific vNAR molecules were produced as soluble proteins and more extensively characterized via thermal shift assays and biolayer interferometry. Essentially, we demonstrate that high-affinity binders can be generated in vitro without largely compromising the desirable high thermostability of the vNAR scaffold.

  7. The fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes.

    Science.gov (United States)

    Wensveen, Felix M; van Gisbergen, Klaas P J M; Eldering, Eric

    2012-09-01

    Lymphocyte activation via the antigen receptor is associated with radical shifts in metabolism and changes in requirements for nutrients and cytokines. Concomitantly, drastic changes occur in the expression of pro-and anti-apoptotic proteins that alter the sensitivity of lymphocytes to limiting concentrations of key survival factors. Antigen affinity is a primary determinant for the capacity of activated lymphocytes to access these vital resources. The shift in metabolic needs and the variable access to key survival factors is used by the immune system to eliminate activated low-affinity cells and to generate an optimal high-affinity response. In this review, we focus on the control of apoptosis regulators in activated lymphocytes by nutrients, cytokines, and costimulation. We propose that the struggle among individual clones that leads to the formation of high-affinity effector cell populations is in effect an 'invisible' fourth signal required for effective immune responses.

  8. Proton Affinity Calculations with High Level Methods.

    Science.gov (United States)

    Kolboe, Stein

    2014-08-12

    Proton affinities, stretching from small reference compounds, up to the methylbenzenes and naphthalene and anthracene, have been calculated with high accuracy computational methods, viz. W1BD, G4, G3B3, CBS-QB3, and M06-2X. Computed and the currently accepted reference proton affinities are generally in excellent accord, but there are deviations. The literature value for propene appears to be 6-7 kJ/mol too high. Reported proton affinities for the methylbenzenes seem 4-5 kJ/mol too high. G4 and G3 computations generally give results in good accord with the high level W1BD. Proton affinity values computed with the CBS-QB3 scheme are too low, and the error increases with increasing molecule size, reaching nearly 10 kJ/mol for the xylenes. The functional M06-2X fails markedly for some of the small reference compounds, in particular, for CO and ketene, but calculates methylbenzene proton affinities with high accuracy.

  9. Classification of neocortical interneurons using affinity propagation

    Science.gov (United States)

    Santana, Roberto; McGarry, Laura M.; Bielza, Concha; Larrañaga, Pedro; Yuste, Rafael

    2013-01-01

    In spite of over a century of research on cortical circuits, it is still unknown how many classes of cortical neurons exist. In fact, neuronal classification is a difficult problem because it is unclear how to designate a neuronal cell class and what are the best characteristics to define them. Recently, unsupervised classifications using cluster analysis based on morphological, physiological, or molecular characteristics, have provided quantitative and unbiased identification of distinct neuronal subtypes, when applied to selected datasets. However, better and more robust classification methods are needed for increasingly complex and larger datasets. Here, we explored the use of affinity propagation, a recently developed unsupervised classification algorithm imported from machine learning, which gives a representative example or exemplar for each cluster. As a case study, we applied affinity propagation to a test dataset of 337 interneurons belonging to four subtypes, previously identified based on morphological and physiological characteristics. We found that affinity propagation correctly classified most of the neurons in a blind, non-supervised manner. Affinity propagation outperformed Ward's method, a current standard clustering approach, in classifying the neurons into 4 subtypes. Affinity propagation could therefore be used in future studies to validly classify neurons, as a first step to help reverse engineer neural circuits. PMID:24348339

  10. Scaling laws in phytoplankton nutrient uptake affinity

    Directory of Open Access Journals (Sweden)

    Christian eLindemann

    2016-03-01

    Full Text Available Nutrient uptake affinity affects the competitive ability of microbial organisms at low nutrient concentrations. From the theory of diffusion limitation it follows that uptake affinity scales linearly with the cell radius. This is in conflict with some observations suggesting that uptake affinity scales to a quantity that is closer to the square of the radius, i.e. to cell surface area. We show that this apparent conflict can be resolved by nutrient uptake theory. Pure diffusion limitation assumes that the cell is a perfect sink which means that it is able to absorb all encountered nutrients instantaneously. Here we provide empirical evidence that the perfect sink strategy is not common in phytoplankton. Although small cells are indeed favored by a large surface to volume ratio, we show that they are punished by higher relative investment cost in order to fully benefit from the larger surface to volume ratio. We show that there are two reasons for this. First, because the small cells need a higher transporter density in order to maximize their affinity, and second because the relative cost of a transporter is higher for a small than for a large cell. We suggest that this might explain why observed uptake affinities do not scale linearly with the cell radius.

  11. Classification of neocortical interneurons using affinity propagation.

    Science.gov (United States)

    Santana, Roberto; McGarry, Laura M; Bielza, Concha; Larrañaga, Pedro; Yuste, Rafael

    2013-01-01

    In spite of over a century of research on cortical circuits, it is still unknown how many classes of cortical neurons exist. In fact, neuronal classification is a difficult problem because it is unclear how to designate a neuronal cell class and what are the best characteristics to define them. Recently, unsupervised classifications using cluster analysis based on morphological, physiological, or molecular characteristics, have provided quantitative and unbiased identification of distinct neuronal subtypes, when applied to selected datasets. However, better and more robust classification methods are needed for increasingly complex and larger datasets. Here, we explored the use of affinity propagation, a recently developed unsupervised classification algorithm imported from machine learning, which gives a representative example or exemplar for each cluster. As a case study, we applied affinity propagation to a test dataset of 337 interneurons belonging to four subtypes, previously identified based on morphological and physiological characteristics. We found that affinity propagation correctly classified most of the neurons in a blind, non-supervised manner. Affinity propagation outperformed Ward's method, a current standard clustering approach, in classifying the neurons into 4 subtypes. Affinity propagation could therefore be used in future studies to validly classify neurons, as a first step to help reverse engineer neural circuits.

  12. Craniodental affinities of Southeast Asia's "negritos" and the concordance with their genetic affinities.

    Science.gov (United States)

    Bulbeck, David

    2013-01-01

    Genetic research into Southeast Asia's "negritos" has revealed their deep-rooted ancestry, with time depth comparable to that of Southwest Pacific populations. This finding is often interpreted as evidence that negritos, in contrast to other Southeast Asians, can trace much of their ancestry directly back to the early dispersal of Homo sapiens in the order of 70 kya from Africa to Pleistocene New Guinea and Australia. One view on negritos is to lump them and Southwest Pacific peoples into an "Australoid" race whose geographic distribution had included Southeast Asia prior to the Neolithic incursion of "Mongoloid" farmers. Studies into Semang osteology have revealed some hints of Southwest Pacific affinities in cranial shape, dental morphology, and dental metrical "shape." On the other hand, the Andamanese have been shown to resemble Africans in their craniometrics and South Asians in their dental morphology, while Philippine negritos resemble Mongoloid Southeast Asians in these respects and also in their dental metrics. This study expands the scope of negrito cranial comparisons by including Melayu Malays and additional coverage of South Asians. It highlights the distinction between the Mongoloid-like Philippine negritos and the Andamanese and Semang (and Senoi of Malaya) with their non-Mongoloid associations. It proposes that the early/mid-Holocene dispersal of the B4a1a mitochondrial DNA clade across Borneo, the Philippines, and Taiwan may be important for understanding the distinction between Philippine and other negritos.

  13. Stepparents' Affinity-Seeking and Affinity-Maintaining Strategies with Stepchildren.

    Science.gov (United States)

    Ganong, Lawrence; Coleman, Marilyn; Fine, Mark; Martin, Patricia

    1999-01-01

    Examines the strategies that stepparents use to develop and maintain affinity with stepchildren and the effects that these strategies have on the development of stepparent-stepchildren relationships. Thirty-one affinity-seeking strategies are identified. Results show that dyadic activities worked best, but it is important that stepchildren…

  14. Stepparents' Affinity-Seeking and Affinity-Maintaining Strategies with Stepchildren.

    Science.gov (United States)

    Ganong, Lawrence; Coleman, Marilyn; Fine, Mark; Martin, Patricia

    1999-01-01

    Examines the strategies that stepparents use to develop and maintain affinity with stepchildren and the effects that these strategies have on the development of stepparent-stepchildren relationships. Thirty-one affinity-seeking strategies are identified. Results show that dyadic activities worked best, but it is important that stepchildren…

  15. Modelling and simulation of affinity membrane adsorption.

    Science.gov (United States)

    Boi, Cristiana; Dimartino, Simone; Sarti, Giulio C

    2007-08-24

    A mathematical model for the adsorption of biomolecules on affinity membranes is presented. The model considers convection, diffusion and adsorption kinetics on the membrane module as well as the influence of dead end volumes and lag times; an analysis of flow distribution on the whole system is also included. The parameters used in the simulations were obtained from equilibrium and dynamic experimental data measured for the adsorption of human IgG on A2P-Sartoepoxy affinity membranes. The identification of a bi-Langmuir kinetic mechanisms for the experimental system investigated was paramount for a correct process description and the simulated breakthrough curves were in good agreement with the experimental data. The proposed model provides a new insight into the phenomena involved in the adsorption on affinity membranes and it is a valuable tool to assess the use of membrane adsorbers in large scale processes.

  16. On Affine Fusion and the Phase Model

    Directory of Open Access Journals (Sweden)

    Mark A. Walton

    2012-11-01

    Full Text Available A brief review is given of the integrable realization of affine fusion discovered recently by Korff and Stroppel. They showed that the affine fusion of the su(n Wess-Zumino-Novikov-Witten (WZNW conformal field theories appears in a simple integrable system known as the phase model. The Yang-Baxter equation leads to the construction of commuting operators as Schur polynomials, with noncommuting hopping operators as arguments. The algebraic Bethe ansatz diagonalizes them, revealing a connection to the modular S matrix and fusion of the su(n WZNW model. The noncommutative Schur polynomials play roles similar to those of the primary field operators in the corresponding WZNW model. In particular, their 3-point functions are the su(n fusion multiplicities. We show here how the new phase model realization of affine fusion makes obvious the existence of threshold levels, and how it accommodates higher-genus fusion.

  17. New opioid affinity labels containing maleoyl moiety.

    Science.gov (United States)

    Szatmári, I; Orosz, G; Rónai, A Z; Makó, E; Medzihradszky, K; Borsodi, A

    1999-01-01

    Opioid receptor binding properties and pharmacological profiles of novel peptides containing maleoyl function were determined in order to develop new affinity labels. Based on the enkephalin structure peptide ligands were synthesized and tested. Both in in vitro receptor binding experiments and pharmacological studies, all ligands showed agonist character with relatively high affinity (Ki values in the nanomolar range) and good to moderate selectivity. Replacement of Gly2 in the enkephalin frame with D-Ala led to higher affinities with a small decrease in selectivity. The longer peptide chains resulted in compounds with high percentage (up to 86%) of irreversible binding. The selectivity pattern of the ligands is in good agreement with the data obtained from the pharmacological assays (guinea pig ileum and mouse vas deferens bioassays). The newly synthesized peptides could be used in further studies in order to determine more detailed characteristics of the ligand-receptor interaction.

  18. Poisson Morphisms and Reduced Affine Poisson Group Actions

    Institute of Scientific and Technical Information of China (English)

    YANG Qi Lin

    2002-01-01

    We establish the concept of a quotient affine Poisson group, and study the reduced Poisson action of the quotient of an affine Poisson group G on the quotient of an affine Poisson G-variety V. The Poisson morphisms (including equivariant cases) between Poisson affine varieties are also discussed.

  19. Phosphopeptide enrichment by immobilized metal affinity chromatography

    DEFF Research Database (Denmark)

    Thingholm, Tine E.; Larsen, Martin R.

    2016-01-01

    Immobilized metal affinity chromatography (IMAC) has been the method of choice for phosphopeptide enrichment prior to mass spectrometric analysis for many years and it is still used extensively in many laboratories. Using the affinity of negatively charged phosphate groups towards positively...... charged metal ions such as Fe3+, Ga3+, Al3+, Zr4+, and Ti4+ has made it possible to enrich phosphorylated peptides from peptide samples. However, the selectivity of most of the metal ions is limited, when working with highly complex samples, e.g., whole-cell extracts, resulting in contamination from...

  20. Periodic cyclic homology of affine Hecke algebras

    CERN Document Server

    Solleveld, Maarten

    2009-01-01

    This is the author's PhD-thesis, which was written in 2006. The version posted here is identical to the printed one. Instead of an abstract, the short list of contents: Preface 5 1 Introduction 9 2 K-theory and cyclic type homology theories 13 3 Affine Hecke algebras 61 4 Reductive p-adic groups 103 5 Parameter deformations in affine Hecke algebras 129 6 Examples and calculations 169 A Crossed products 223 Bibliography 227 Index 237 Samenvatting 245 Curriculum vitae 253

  1. Affine Invariant Character Recognition by Progressive Removing

    Science.gov (United States)

    Iwamura, Masakazu; Horimatsu, Akira; Niwa, Ryo; Kise, Koichi; Uchida, Seiichi; Omachi, Shinichiro

    Recognizing characters in scene images suffering from perspective distortion is a challenge. Although there are some methods to overcome this difficulty, they are time-consuming. In this paper, we propose a set of affine invariant features and a new recognition scheme called “progressive removing” that can help reduce the processing time. Progressive removing gradually removes less feasible categories and skew angles by using multiple classifiers. We observed that progressive removing and the use of the affine invariant features reduced the processing time by about 60% in comparison to a trivial one without decreasing the recognition rate.

  2. Control and estimation of piecewise affine systems

    CERN Document Server

    Xu, Jun

    2014-01-01

    As a powerful tool to study nonlinear systems and hybrid systems, piecewise affine (PWA) systems have been widely applied to mechanical systems. Control and Estimation of Piecewise Affine Systems presents several research findings relating to the control and estimation of PWA systems in one unified view. Chapters in this title discuss stability results of PWA systems, using piecewise quadratic Lyapunov functions and piecewise homogeneous polynomial Lyapunov functions. Explicit necessary and sufficient conditions for the controllability and reachability of a class of PWA systems are

  3. Separation of Proteins by Electrophoretic Affinity Chromatography

    Institute of Scientific and Technical Information of China (English)

    邺韶骅; 刘铮; 丁富新; 袁乃驹

    1999-01-01

    A new kind of electrophoretic affinity chromatography (EAC) for bioseparation was proposed,Separation by EAC was conducted in a multicompartment electrolyzer in which the affinity gel media were packed in one of the central compartments.The presence of an electric field accelerated the migration of proteins inside the gel matrix during adsorption and descrption processes,This led to the increase of the overall speed of separation,The present study was focused on the effect of the strength of the electric field on adsorption and desorption processes.

  4. Adsorption affinity of anions on metal oxyhydroxides

    Science.gov (United States)

    Pechenyuk, S. I.; Semushina, Yu. P.; Kuz'mich, L. F.

    2013-03-01

    The dependences of anion (phosphate, carbonate, sulfate, chromate, oxalate, tartrate, and citrate) adsorption affinity anions from geometric characteristics, acid-base properties, and complex forming ability are generalized. It is shown that adsorption depends on the nature of both the anions and the ionic medium and adsorbent. It is established that anions are generally grouped into the following series of adsorption affinity reduction: PO{4/3-}, CO{3/2-} > C2O{4/2-}, C(OH)(CH2)2(COO){3/3-}, (CHOH)2(COO){2/2-} > CrO{4/2-} ≫ SO{4/2-}.

  5. Einstein's gravity from an affine model

    CERN Document Server

    Castillo-Felisola, Oscar

    2015-01-01

    We show that the effective field equations for a recently formulated affine model of gravity, in the sector of a metric (torsion-free) connection, accept general Einstein manifolds --- with or without cosmological constant --- as solutions. Moreover, these effective field equations coincide with the ones obtained from a gravitational Yang--Mills theory known as Stephenson--Kilmister--Yang theory. Additionally, we find an equivalence between a minimally coupled massless scalar field in General Relativity with a "minimally" coupled scalar field in this affine model.

  6. Genetic affinities of Ukrainians from the maternal perspective.

    Science.gov (United States)

    Pshenichnov, Andrey; Balanovsky, Oleg; Utevska, Olga; Metspalu, Ene; Zaporozhchenko, Valery; Agdzhoyan, Anastasia; Churnosov, Mikhail; Atramentova, Lyubov; Balanovska, Elena

    2013-12-01

    The area of what is now the Ukraine has been the arena of large-scale demographic processes that may have left their traces in the contemporary gene pool of Ukrainians. In this study, we present new mitochondrial DNA data for 607 Ukrainians (hypervariable segment I sequences and coding region polymorphisms). To study the maternal affinities of Ukrainians at the level of separate mitochondrial haplotypes, we apply an original technique, the haplotype co-occurrence analysis. About 20% of the Ukrainian maternal gene pool is represented by lineages highly specific to Ukrainians, but is scarcely found in other populations. About 9% of Ukrainian mtDNA lineages are typical for peoples of the Volga region. We also identified minor gene pool strata (1.6-3.3%), each of which is common in Lithuanians, Estonians, Saami, Nenets, Cornish, and the populations of the North Caucasus.

  7. Evidence of multi-affinity in the Japanese stock market

    Science.gov (United States)

    Katsuragi, Hiroaki

    2000-04-01

    Fluctuations of the Japanese stock market (Tokyo Stock Price Index: TOPIX) are analyzed using a multi-affine analysis method. In the research to date, only some simulated self-affine models have shown multi-affinity. In most experiments using observations of self-affine fractal profiles, multi-affinity has not been found. However, we find evidence of multi-affinity in fluctuations of the Japanese stock market (TOPIX). The qth-order Hurst exponent Hq varies with changes in q. This multi-affinity indicates that there are plural mechanisms that affect the same time scale as stock market price fluctuation dynamics.

  8. Crossing Chris: Some Markerian Affinities

    Directory of Open Access Journals (Sweden)

    Adrian Martin

    2010-01-01

    -pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

    Abstract (E: This essay creatively explores a group of artists, writers, and other special individuals whose work or life story can be described as having an intriguing affinity with the protean career of Chris Marker. Avoiding the ‘usual suspects’ (such as Godard or Sebald, it discusses gossip columnist Milt Machlin, record collector Harry Smith, painter Gianfranco Baruchello, writer-filmmaker Edgardo Cozarinsky, and several others. From this constellation, a particular view of Markerian poetics emerges, touching upon the meanings of anonymity, storytelling, history and archiving.

     

    Abstract (F: Cet essai brosse de manière créative le portrait d’un groupe d'artistes, d'écrivains et d'autres personnes particulières dont le travail ou la biographie peuvent être décrits comme montrant une étrange mais certaine connivence avec la carrière protéiforme de Chris Marker. Evitant les lieux communs (comme Godard ou Sebald, cet article trace des références moins attendues :

  9. Note préliminaire sur quelques flores Stéphaniennes de la bordure nord des Léonides dans les montagnes Cantabriques. (Espagne du Nord-Ouest)

    NARCIS (Netherlands)

    Amerom, van H.W.J.

    1965-01-01

    Dans le cadre des recherches géologiques effectuées dans le nord-ouest de l’Espagne par l’Institut géologique de Leiden, une collection de plantes carbonifères a été rassemblée au cours de l’été des années 1960, 1961, 1962 et 1963. Toutes les flores proviennent de quelques petits bassins

  10. Organización de la comunidad de colibríes ermitaños (Trochilidae phaethorninae y sus flores en bosques de tierra firme del Parque Nacional Natural Amacayacu (Amazonas, Colombia

    Directory of Open Access Journals (Sweden)

    Rodríguez Flores Claudia Isabel

    2004-12-01

    Full Text Available Se determinó la organización de la comunidad de colibríes ermitaños y sus recursos en bosques de tierra firme de la Amazonia colombiana, a partir de observaciones directas a las flores, cargas de polen de los ermitaños, medidas morfológicas de colibríes y flores, y conteo de flores
    en cinco sitios diferentes. La comunidad la conformaron siete especies de ermitaños (Phaethornis malaris, P. hispidus, P. bourcieri, P. atrimentalis, P. ruber, Glaucis hirsuta y Threnetes leucurus, y 44 especies vegetales (Heliconiaceae, Gesneriaceae, Rubiaceae, Acanthaceae y Costaceae, fueron las familias con mayor número de especies. Los patrones de forrajeo de los colibríes permitieron separar la comunidad en cuatro grupos de ermitaños y plantas, donde el ajuste morfológico y la intensidad de uso del recurso aparecieron como factores explicativos de las agrupaciones: Phaethornis bourcieri, P. atrimentalis y P. ruber, junto con los recursos más intensamente visitados por estos, formó cada uno una asociación; mientras que Glaucis hirsuta, Threnetes leucurus,
    Phaethornis hispidus y P. malaris, junto a 33 recursos, conformaron un cuarto grupo. Los patrones de forrajeo de las especies estuvieron influenciados adicionalmente por la oferta del recurso (número de flores y las características del hábitat. Interacciones más fuertes entre grupos de
    colibríes con ciertos grupos de plantas apoyaron la hipótesis de la coevolución difusa como mecanismo modelador de las interacciones en esta comunidad.

  11. Abelhas (Hymenoptera: apoidea visitantes das flores de goiaba em pomar comercial in Salinas, MG Bee diversity in a commercial guava orchard in Salinas, Minas Gerais State, Brazil

    Directory of Open Access Journals (Sweden)

    Rosemeire Alves Guimarães

    2009-01-01

    Full Text Available As abelhas são responsáveis por cerca de 80% a 100% da polinização de culturas agrícolas, especialmente aquelas relacionadas com a produção de sementes e frutos. A investigação da diversidade de abelhas em pomares de goiaba pode ser subsídio para estratégias de incremento da produtividade. Nesta perspectiva, o objetivo deste estudo foi identificar a diversidade de abelhas visitantes das flores de goiaba (Psidium guajava, em pomar comercial em Salinas (MG. O trabalho foi desenvolvido em maio de 2005 e foram coletadas as abelhas visitantes das flores nos horários entre 6h e 18h, totalizando-se 44 horas de coleta. Coletaram-se 705 abelhas de 17 espécies, sendo Trigona spinipes a mais freqüente e dominante na cultura da goiaba. Apis mellifera, Melipona quadrifasciata e Tetragonisca angustula foram consideradas acessórias. Aproximadamente 84% dos indivíduos foram coletados da manhã, de 6h às 10h.Pollination is an important factor in agricultural systems, especially in growing fruits and seed production, which depend greatly on bee visiting during blossom season; highly successful gains within these activities varies between 80 and nearly 100 per cent, owing to the bees. The assessment of bee diversity in commercial orchards of guava may contribute to a more desirable strategic design and consequent improvement of production. The aim of the study was identify the diversity of visiting bees to guava flowers (Psidium guajava in a commercial orchard in Salinas, State of Minas Gerais, Brazil. The work was carried during blossom season of May - 2005. Field works occurred between 6:00 am to 6:00 pm, counting with 44 hours of collection, when 705 bees were collected. The richness observed was of 17 species, the most frequent and dominant being Trigona spinipes. Among the collection there were some considered accessory species: Apis mellifera, Melipona quadrifasciata and Tetragonisca angustula. Most of individual bees have been captured

  12. Post-harvest longevity of Oncidium varicosum (Orchidaceae flowers/ Longevidade pós-colheita de flores de Oncidium varicosum (Orchidaceae

    Directory of Open Access Journals (Sweden)

    Ricardo Tadeu Faria

    2006-06-01

    Full Text Available Oncidium varicosum from the Orchidaceae family has been widely used as pot flower, and, most recently, as cut flower. The objective of this work was to evaluate the longevity of the Oncidium varicosum, due to its low post-harvest resistance, after being conditioned in preservation solutions with different concentrations of sucrose. Oncidium varicosum stems grown in Holambra (SP were transported to Londrina (PR in climatized trucks at 5-7oC. Pre-treatment with pulsing (15% sucrose for 24 hours followed by conditioning in maintenance solution (1, 2, 3, and 4% of sucrose as well as conditioning in maintenance solution without pre-treatment were evaluated. Flower stems were distributed in an entirely casualized design, with ten treatments and five replications. Flowers were evaluated daily, using a score system developed to compare and verify the conservation of visual aspects. No treatment was superior to the control in maintaining the longevity of the flowers.A orquídea Oncidium varicosum é bastante utilizada como flor de vaso e atualmente vem se destacando como flor de corte. Devido sua baixa resistência pós-colheita, o objetivo deste trabalho foi avaliar a longevidade de Oncidium varicosum após o acondicionamento em soluções conservantes com diferentes concentrações de sacarose. As hastes de Oncidium varicosum, produzidas em Holambra (SP, foram transportadas para Londrina (PR em caminhão climatizado a 5-7°C. Foram avaliadas a utilização de prétratamento com “pulsing” (15% de sacarose por 24 horas seguido de acondicionamento em solução de manutenção (1, 2, 3 e 4% de sacarose e o acondicionamento em solução de manutenção sem prétratamento. As hastes florais foram distribuídas em delineamento inteiramente casualizado, com dez tratamentos e cinco repetições. As avaliações das flores foram diárias, sob critério de notas definido para comparar e verificar a conservação dos aspectos visuais. Nenhum dos tratamentos

  13. Angiogenic activity of Calendula officinalis flowers L. in rats Atividade angiogênica das flores da Calendula officinalis L. em ratos

    Directory of Open Access Journals (Sweden)

    Leila Maria Leal Parente

    2011-02-01

    Full Text Available Purpose: In this work, angiogenic activity of Calendula officinalis L. (Asteraceae ethanolic extract and dichloromethane and hexanic fractions were evaluated, considering medicinal properties, especially healing activity, are attributed to this plant. Methods: Models using 36 rats and 90 embryonated eggs were used to evaluate healing and angiogenic activities of extracts and fractions of the plant, through the induction of skin wounds and the chorioallantoic membrane, respectively. The effect of vascular proliferation was also tested from the study to verify the intensity of expression of vascular endothelial growth factor (VEGF in cutaneous wounds in rats. Results: The angiogenic activity of the extract and the fractions was evidenced in both experimental models. It was verified that this effect is not directly related to the expression of VEGF and it could be associated to other pro-angiogenic factors. Conclusion: The healing activity referred to C. officinalis is related, among other factors, to its positive effect on angiogenesis, characterized by the induction of neovascularization.Objetivo: Neste trabalho a atividade sobre a angiogênese do extrato etanólico (EEC e das frações diclorometano e hexânica das flores de Calendula officinalis L. (Asteraceae cultivada no Brasil foram avaliados, visto que propriedades medicinais têm sido atribuídas às flores da planta, destacando-se a atividade cicatrizante. Métodos: Modelos utilizando 36 ratos e 90 ovos embrionados foram usados para avaliar as atividades cicatrizante e angiogênica dos extratos e frações da planta, por meio da indução de feridas cutâneas e da membrana corioalantóide, respectivamente. O efeito proliferativo vascular foi também testado a partir do estudo imunoistoquímico, realizado para verificar a intensidade da expressão do fator de crescimento endotelial vascular (VEGF na derme de ratos. Resultados: A atividade angiogênica do extrato e das frações foi

  14. CARACTERIZACIÓN DE LA DIVERSIDAD DE CULTIVOS CON VISTAS A LA ADOPCIÓN DE NUEVAS ESPECIES Y/O VARIEDADES DE FLORES DE CORTE EN DIFERENTES SISTEMAS PRODUCTIVOS DEL MUNICIPIO SAN JOSÉ DE LAS LAJAS

    Directory of Open Access Journals (Sweden)

    Ania Yong

    2007-01-01

    Full Text Available Se realizó un trabajo de diagnóstico con el objetivo de caracterizar la diversidad de cultivos en huertos, parcelas y patios de los Consejos Norte, Sur y Jamaica de San José de las Lajas, con vistas a la selección participativa, adaptación o adopción de nuevas especies y variedades de flores de corte, en sistemas de producción de la agricultura urbana del municipio. Los principales cultivos establecidos en los diferentes sistemas productivos fueron las hortalizas, seguido por los frutales y las flores. De manera general, puede considerarse que los conocimientos acerca de las tecnologías de producción de flores aún son insuficientes, aunque se realiza un trabajo de capacitación con los productores, de acuerdo con sus necesidades y condiciones, fomentando el empleo de tecnologías adecuadas para el incremento de sus producciones. A través de las encuestas realizadas a los productores, también se pudo conocer que el 80 % sobrepasa los 60 años de edad, existen diferentes niveles de estudio y únicamente tres de ellos son del territorio.

  15. Colliding waves in metric-affine gravity

    CERN Document Server

    García, A; Macías, A; Mielke, E W; Socorro, J; García, Alberto; Lämmerzahl, Claus; Macías, Alfredo; Mielke, Eckehard W.; Socorro, José

    1998-01-01

    We generalize the formulation of the colliding gravitational waves to metric-affine theories and present an example of such kind of exact solutions. The plane waves are equipped with five symmetries and the resulting geometry after the collision possesses two spacelike Killing vectors.

  16. Classification of neocortical interneurons using affinity propagation

    Directory of Open Access Journals (Sweden)

    Roberto eSantana

    2013-12-01

    Full Text Available In spite of over a century of research on cortical circuits, it is still unknown how many classes of cortical neurons exist. Neuronal classification has been a difficult problem because it is unclear what a neuronal cell class actually is and what are the best characteristics are to define them. Recently, unsupervised classifications using cluster analysis based on morphological, physiological or molecular characteristics, when applied to selected datasets, have provided quantitative and unbiased identification of distinct neuronal subtypes. However, better and more robust classification methods are needed for increasingly complex and larger datasets. We explored the use of affinity propagation, a recently developed unsupervised classification algorithm imported from machine learning, which gives a representative example or exemplar for each cluster. As a case study, we applied affinity propagation to a test dataset of 337 interneurons belonging to four subtypes, previously identified based on morphological and physiological characteristics. We found that affinity propagation correctly classified most of the neurons in a blind, non-supervised manner. In fact, using a combined anatomical/physiological dataset, our algorithm differentiated parvalbumin from somatostatin interneurons in 49 out of 50 cases. Affinity propagation could therefore be used in future studies to validly classify neurons, as a first step to help reverse engineer neural circuits.

  17. Vygotsky's and Buber's Pedagogical Perspectives: Some Affinities

    Science.gov (United States)

    Bartholo, Roberto; Tunes, Elizabeth; Tacca, Maria Carmen Villela Rosa

    2010-01-01

    The purpose of this paper is to examine the dialogical and creative character of pedagogic work by analyzing the affinities between Martin Buber's "I-Thou relation" and Lev Semenovich Vygotsky's "Zone of Proximal Development". Backed up by empirical studies on the teacher-student relation, we understand that education can only result in students'…

  18. Fan Affinity Laws from a Collision Model

    Science.gov (United States)

    Bhattacharjee, Shayak

    2012-01-01

    The performance of a fan is usually estimated using hydrodynamical considerations. The calculations are long and involved and the results are expressed in terms of three affinity laws. In this paper we use kinetic theory to attack this problem. A hard sphere collision model is used, and subsequently a correction to account for the flow behaviour…

  19. Fan Affinity Laws from a Collision Model

    Science.gov (United States)

    Bhattacharjee, Shayak

    2012-01-01

    The performance of a fan is usually estimated using hydrodynamical considerations. The calculations are long and involved and the results are expressed in terms of three affinity laws. In this paper we use kinetic theory to attack this problem. A hard sphere collision model is used, and subsequently a correction to account for the flow behaviour…

  20. Affine Quantization and the Initial Cosmological Singularity

    CERN Document Server

    Fanuel, Michaël

    2012-01-01

    A toy model for quantum cosmology is suggested and quantized in the light of the Affine Coherent State Quantization procedure. The quantum corrections to the classical dynamics seem to provide a potential barrier term, as already suggested in other models studied in the literature. The possible application of this method to more realistic minisuperspace models is envisaged.

  1. Modern affinity reagents: Recombinant antibodies and aptamers.

    Science.gov (United States)

    Groff, Katherine; Brown, Jeffrey; Clippinger, Amy J

    2015-12-01

    Affinity reagents are essential tools in both basic and applied research; however, there is a growing concern about the reproducibility of animal-derived monoclonal antibodies. The need for higher quality affinity reagents has prompted the development of methods that provide scientific, economic, and time-saving advantages and do not require the use of animals. This review describes two types of affinity reagents, recombinant antibodies and aptamers, which are non-animal technologies that can replace the use of animal-derived monoclonal antibodies. Recombinant antibodies are protein-based reagents, while aptamers are nucleic-acid-based. In light of the scientific advantages of these technologies, this review also discusses ways to gain momentum in the use of modern affinity reagents, including an update to the 1999 National Academy of Sciences monoclonal antibody production report and federal incentives for recombinant antibody and aptamer efforts. In the long-term, these efforts have the potential to improve the overall quality and decrease the cost of scientific research. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Binding affinities of anti-acetylcholine receptor autoantibodies in myasthenia gravis

    Energy Technology Data Exchange (ETDEWEB)

    Bray, J.J.; Drachman, D.B.

    1982-01-01

    Antibodies directed against acetylcholine (ACh) receptors are present in the sera of nearly 90% of patients with myasthenia gravis (MG), and are involved in the pathogenesis of this autoimmune disease. However, the antibody titers measured by the standard radioimmunoassay correspond poorly with the clinical severity of the disease. To determine whether this disparity could be accounted for by differences in the binding affinities of anti-ACh receptor antibodies in different patients, we have measured the binding affinities of these autoantibodies in 15 sera from MG patients. The affinity constants (K/sub o/), as determined by Scatchard analysis, were all in the range of 10/sup 10/ M/sup -1/, comparable to the highest values reported in immunized animals. The affinity constants were truly representative of the population of autoantibodies detected by the radioimmunoassay, as shown by the remarkable linearity of the Scatchard plots (r/sup 2/>0.90) and the close correlation between the antibody titers determined by extrapolation of the Scatchard plots and by saturation analysis (r = 0.99; p < 0.001). There was only a 6-fold variation in affinity constants measured in this series of patients despite widely differing antibody titers and severity of the disease. Factors other than the titer and affinity of anti-ACh receptor antibodies may correlate better with the clinical manifestations of MG.

  3. Congophilicity (Congo red affinity) of different beta2-microglobulin conformations characterized by dye affinity capillary electrophoresis

    DEFF Research Database (Denmark)

    Heegaard, N H; Sen, J W; Nissen, Mogens Holst

    2000-01-01

    The amyloidogenic protein beta-microglobulin was characterized by affinity capillary electrophoresis (CE). CE could separate conformational variants of beta2-microglobulin and with the amyloid-specific dye Congo red as a buffer additive it was possible to measure different Congo red-affinities of......The amyloidogenic protein beta-microglobulin was characterized by affinity capillary electrophoresis (CE). CE could separate conformational variants of beta2-microglobulin and with the amyloid-specific dye Congo red as a buffer additive it was possible to measure different Congo red...

  4. Efeito da desfolha de ramos sobre a indução de brotos e flores em atemóia (Anonna cherimola Mill x Anonna squamosa L.

    Directory of Open Access Journals (Sweden)

    Lemos Eurico Eduardo Pinto de

    2003-01-01

    Full Text Available Avaliou-se o efeito do desfolhamento de ramos na produção de brotos e flores em plantas adultas de atemóia (Anonna cherimola Mill x Anonna squamosa L. var. Gefner. O experimento foi realizado em plantio comercial no município de Maceió - AL. Foram utilizadas 24 plantas podadas com altura de 1.5 m e espaçadas de 4 x 2 m. Os ramos maduros tiveram seus ápices removidos na altura da 4ª folha, sendo depois submetidos aos seguintes tratamentos de desfolha manual: 1 desfolha total dos ramos; 2 remoção das cinco primeiras folhas dos ramos a partir dos ápices podados; 3 remoção de cinco folhas compreendidas entre 6ª a 10ª gemas dos ramos; 4 controle = sem desfolha dos ramos. Os resultados coletados 30 dias após a desfolha mostraram que o número de brotações nos tratamentos com desfolha total e desfolha das cinco gemas superiores foi estatisticamente superior aos tratamentos sem desfolha e desfolha da 6ª à 10ª gema. O tratamento com desfolha das cinco gemas superiores apresentou o maior número de ramos florados (61%.

  5. Etnografías de la Muerte y las Culturas en América Latina (Juan Antonio Flores Martos y Luisa Abad González, Coord.

    Directory of Open Access Journals (Sweden)

    Lorenzo Mariano Juárez

    2008-05-01

    Full Text Available Curiosamente, la muerte ha sido usualmente pensada y construida desde perspectivas y lógicas universalizadoras como uno de los escasos acontecimientos comunes a la humanidad, una visión estruendosa que ha dotado a la muerte de cierto carácter homogeneizador que en muchas ocasiones vela sentimientos y opaca la riqueza que atesoran matices y susurros particulares. Mucho tiempo ha transcurrido desde el trabajo pionero en antropología de Robert Hertz y la muerte se ha constituido en estas décadas como un campo temático clásico de la disciplina. Los coordinadores de este libro, Juan Antonio Flores Martos y Luisa Abad González –de la Universidad de Castilla-La Mancha- , hoy lo hacen presente, presentándonos una serie de trabajos encaminados hacia la ruptura de esa visión uniforme y gris de la muerte en el contexto general de la actual y convulsa América Latina.

  6. USAHA PENANGGULANGAN VEKTOR MALARIA DAN FILARIASIS MELALUI PENYULUHAN KESEHATAN DI SEKOLAH DASAR DI KECAMATAN WULANGGITANG, KABUPATEN FLORES TIMUR NUSA TENGGARA TIMUR

    Directory of Open Access Journals (Sweden)

    Suskamdani Suskamdani

    2012-09-01

    Full Text Available A study to evaluate the effectiveness of school health education for mosquito borne diseases vector control program was conducted in East Flores Regency, East Nusa Tenggara Province. The method of study include education program for the teachers and 4th through 6th grade students from 2 primary schools and another school in the area was chosen as control. The evaluation was made through responses obtained from the questionaires given before and after the education program for malaria and filariasis regarding their sign, symptoms, the vector and prevention. The results show that there are 3,82% and 4,10% increase in knowledge about malaria and filaria respectively after the education program. This means the education material was well accepted. Although there was an overall increase in knowledge about malaria, no similar response was noted for filariasis. Thus the education material for filariasis should be improved. The result of the study suggest that a continous education program for malaria and filariasis should be incorporated into the regular School Health Education curicullum in the endemic areas.

  7. DIVERSIDAD DE LEVADURAS ASOCIADAS A INFLORESCENCIAS DE MANGO Y FLORES DE 'LULO ARBÓREO' DIVERSIDADE DE LEVEDURAS ASSOCIADAS A INFLORESCÊNCIAS DE MANGA E FLORES DE 'LULO ARBÓREO' YEAST DIVERSITY ASSOCIATED TO INFLORESCENCES OF MANGO AND FLOWERS OF 'LULO ARBOREO'

    Directory of Open Access Journals (Sweden)

    JACKELINE GAVIRIA V.

    2012-12-01

    Full Text Available En Colombia, el conocimiento de levaduras ha sido limitado a especies de interés clínico. El micro-hábitat aéreo de las flores, presenta un área de gran interés para el aislamiento de levaduras con importancia en el campo industrial, por su potencial uso como controlador biológico. El objetivo de este trabajo es analizar la diversidad de levaduras asociadas a inflorescencia de Mango (Mangífera índica y flores de Lulo arbóreo (Solanum wrightii. Para dicha finalidad se trabajó con 96 aislados, a los cuales se les realizó caracterización fenotípica y posteriores pruebas de MSP-PCR Fingerprinting. Estas pruebas fueron complementadas con amplificación parcial y secuenciación del segmento 26S del ADNr para identificación a nivel de especie. El patrón de diversidad encontrado refleja una dominancia de la especie Candida leandrae en flores de lulo arbóreo, también se presentaron especies como Cryptococcus laurentii, Candida parazyma, Aeurobasidium pullulans y Pseudozyma tsukubaensis. Las inflorescencias de mango presentaron especies como Sydowia eucalypti, Cryptococcus flavescens, C. laurentii, C. nemorosus, C. heveanensis, Pichia kluyveri, Pseudozyma tsukubaensis y Candida asparagi. Se logró identificar hasta el nivel taxonómico de especie el total de los aislados encontrados, además se hallaron especies con potencial uso biotecnológico.Na Colômbia, o conhecimento das leveduras é limitado a espécies de interesse clinico. O micro-habitat aéreo das flores apresenta um interessante campo para o isolamento de leveduras com importância na indústria pelo seu potencial uso em controle biológico. O objetivo deste trabalho foi analisar a diversidade de leveduras associadas a inflorescências de Manga (Mangifera indica e flores de 'lulo' (Solanum wrightii. Para isso, foram analisados 96 isolados, que foram caracterizados com testes fenotípicos e MSP-PCR Fingerprinting complementadas com sequenciamento parcial da região 26S do r

  8. Boronic acid lectin affinity chromatography (BLAC). 2. Affinity micropartitioning-mediated comparative glycosylation profiling.

    Science.gov (United States)

    Monzo, Alex; Olajos, Marcell; De Benedictis, Lorenzo; Rivera, Zuly; Bonn, Guenther K; Guttman, András

    2008-09-01

    As a continuation of our work on boronic acid lectin affinity chromatography (BLAC), in this paper we introduce an automated affinity micropartitioning approach using combined boronic acid and concanavalin A (BLAC/Con A) resin-filled micropipette tips to isolate and enrich human serum glycoproteins. The N-linked oligosaccharides of the partitioned glycoproteins were removed by PNGase F enzyme digestion, followed by 8-aminopyrene-1,3,6-trisulfonic acid labeling. Capillary gel electrophoresis with blue LED-induced fluorescence detection was applied in a multiplexed format for comparative glycan profiling. The efficiency of BLAC affinity micropartitioning was compared with that of the individual lectin and pseudolectin affinity enrichment. Finally, we report on our findings in glycosylation differences in human serum samples from healthy and prostate cancer patients by applying BLAC/Con A micropipette tip-based enrichment and comparative multicapillary gel electrophoresis analysis of the released and labeled glycans.

  9. Étude des vestiges ligneux et leur apport à la connaissance de la dynamique de la flore et de l’architecture ancienne grassfields à l’Ouest -Cameroun

    Directory of Open Access Journals (Sweden)

    Bienvenu Denis Nizesete

    2015-02-01

    Full Text Available

    Résumé: Entre 1988 et 2012, nous avons prélevé dans la région de l’Ouest-Cameroun, 450 fragments ligneux sur divers anciens objets manufacturés. Ils ont ensuite fait l’objet d’une identification anatomique en vue de la détermination botanique des arbres d’où ils étaient issus. Les analyses scientifiques dans des laboratoires spécialisés, ont révélé la présence des essences de bois aux caractéristiques physiques, mécaniques, technologiques et esthétiques plurielles et convenant aux usages les plus variés. Elles ont également permis d’observer la présence de certaines espèces d’arbres caractéristiques d’une flore forestière aujourd’hui disparue dans les Grassfields. De ce fait, il ressort que la flore forestière primaire de l’Ouest- Cameroun a progressivement cédé la place à un couvert végétal moins arborescent. Sous l’effet de plusieurs siècles de déboisement intensif, conduite par une population anciennement installée et à la croissance démographique soutenue, le potentiel ligneux a connu une forte réduction mais n’a pas totalement disparu. Dans les lambeaux de ce couvert végétal composite en mutation constante, les hommes ont exploité des arbres aux caractéristiques physiques, mécaniques, technologiques et esthétiques diverses. Leur parfaite connaissance de ces ressources, fruit de plusieurs siècles d’observation et d’expérience, leur a permis d’affecter avec compétence, un bois donné à un usage particulier: sculpture, architecture, récipients, tabourets, outils agricoles, ponts, combustibles, etc. L’étude particulière de l’architecture à travers la case bamiléké, est une parfaite illustration du savoir et du savoir-faire des artisans bamiléké, en matière de gestion des ressources ligneuses dans un environnement naturel dynamique et dans un secteur d’activité requérant pour chacune de ses composantes, des bois adaptés à des usages sp

  10. Local structure of self-affine sets

    CERN Document Server

    Bandt, Christoph

    2011-01-01

    The structure of a self-similar set with open set condition does not change under magnification. For self-affine sets the situation is completely different. We consider planar self-affine Cantor sets E of the type studied by Bedford, McMullen, Gatzouras and Lalley, for which the projection onto the horizontal axis is an interval. We show that within small square neighborhoods of almost each point x in E, with respect to many product measures on address space, E is well approximated by product sets of an interval and a Cantor set. Even though E is totally disconnected, the limit sets have the product structure with interval fibres, reminiscent to the view of attractors of chaotic differentiable dynamical systems.

  11. Artificial Affinity Proteins as Ligands of Immunoglobulins

    Directory of Open Access Journals (Sweden)

    Barbara Mouratou

    2015-01-01

    Full Text Available A number of natural proteins are known to have affinity and specificity for immunoglobulins. Some of them are widely used as reagents for detection or capture applications, such as Protein G and Protein A. However, these natural proteins have a defined spectrum of recognition that may not fit specific needs. With the development of combinatorial protein engineering and selection techniques, it has become possible to design artificial affinity proteins with the desired properties. These proteins, termed alternative scaffold proteins, are most often chosen for their stability, ease of engineering and cost-efficient recombinant production in bacteria. In this review, we focus on alternative scaffold proteins for which immunoglobulin binders have been identified and characterized.

  12. Weight Representations of Admissible Affine Vertex Algebras

    Science.gov (United States)

    Arakawa, Tomoyuki; Futorny, Vyacheslav; Ramirez, Luis Enrique

    2017-08-01

    For an admissible affine vertex algebra {V_k{(\\mathfrak{g})}} of type A, we describe a new family of relaxed highest weight representations of {V_k{(\\mathfrak{g})}}. They are simple quotients of representations of the affine Kac-Moody algebra {\\widehat{\\mathfrak{g}}} induced from the following {\\mathfrak{g}}-modules: (1) generic Gelfand-Tsetlin modules in the principal nilpotent orbit, in particular all such modules induced from {\\mathfrak{sl}_2}; (2) all Gelfand-Tsetlin modules in the principal nilpotent orbit that are induced from {\\mathfrak{sl}_3}; (3) all simple Gelfand-Tsetlin modules over {\\mathfrak{sl}_3}. This in particular gives the classification of all simple positive energy weight representations of {V_k{(\\mathfrak{g})}} with finite dimensional weight spaces for {\\mathfrak{g}=\\mathfrak{sl}_3}.

  13. Integrating Structured Metadata with Relational Affinity Propagation

    CERN Document Server

    Plangprasopchok, Anon; Getoor, Lise

    2010-01-01

    Structured and semi-structured data describing entities, taxonomies and ontologies appears in many domains. There is a huge interest in integrating structured information from multiple sources; however integrating structured data to infer complex common structures is a difficult task because the integration must aggregate similar structures while avoiding structural inconsistencies that may appear when the data is combined. In this work, we study the integration of structured social metadata: shallow personal hierarchies specified by many individual users on the SocialWeb, and focus on inferring a collection of integrated, consistent taxonomies. We frame this task as an optimization problem with structural constraints. We propose a new inference algorithm, which we refer to as Relational Affinity Propagation (RAP) that extends affinity propagation (Frey and Dueck 2007) by introducing structural constraints. We validate the approach on a real-world social media dataset, collected from the photosharing website ...

  14. Recent Results Regarding Affine Quantum Gravity

    CERN Document Server

    Klauder, John R

    2012-01-01

    Recent progress in the quantization of nonrenormalizable scalar fields has found that a suitable non-classical modification of the ground state wave function leads to a result that eliminates term-by-term divergences that arise in a conventional perturbation analysis. After a brief review of both the scalar field story and the affine quantum gravity program, examination of the procedures used in the latter surprisingly shows an analogous formulation which already implies that affine quantum gravity is not plagued by divergences that arise in a standard perturbation study. Additionally, guided by the projection operator method to deal with quantum constraints, trial reproducing kernels are introduced that satisfy the diffeomorphism constraints. Furthermore, it is argued that the trial reproducing kernels for the diffeomorphism constraints may also satisfy the Hamiltonian constraint as well.

  15. Folding defect affine Toda field theories

    CERN Document Server

    Robertson, C

    2013-01-01

    A folding process is applied to fused a^(1)_r defects to construct defects for the non-simply laced affi?ne Toda ?field theories of c^(1)_n, d^(2)_n and a^(2)_n at the classical level. Support for the hypothesis that these defects are integrable in the folded theories is provided by the observation that transmitted solitons retain their form. Further support is given by the demonstration that energy and momentum are conserved.

  16. Mepanipyrim haptens and antibodies with nanomolar affinity

    OpenAIRE

    Esteve Turrillas, Francesc Albert; Mercader Badia, Josep Vicent; Agulló, Consuelo; Abad Somovilla, Antonio; Abad Fuentes, Antonio

    2013-01-01

    Mepanipyrim is an anilinopyrimidine fungicide used worldwide for crop protection. With the aim of developing useful immunoreagents for mepanipyrim immunoanalysis, two new functionalized derivatives were prepared and antibodies were generated. Affinity and specificity were assessed by direct and indirect competitive ELISA using homologous and heterologous conjugates. Although all antibodies were selective for the target analyte, the immunizing hapten structure was revealed as a determinant for...

  17. Couplings in Affine Toda Field Theories

    OpenAIRE

    1992-01-01

    We present a systematic derivation for a general formula for the n-point coupling constant valid for affine Toda theories related to any simple Lie algebra {\\bf g}. All n-point couplings with $n \\geq 4$ are completely determined in terms of the masses and the three-point couplings. A general fusing rule, formulated in the root space of the Lie algebra, is derived for all n-point couplings.

  18. Thermodynamics. Using Affinities to define reversible processes

    CERN Document Server

    Ritacco, Hernán A

    2016-01-01

    In this article a definition of reversible processes in terms of differences in intensive Thermodynamics properties (Affinities) is proposed. This definition makes it possible to both define reversible processes before introducing the concept of entropy and avoid the circularity problem that follows from the Clausius definition of entropy changes. The convenience of this new definition compared to those commonly found in textbooks is demonstrated with examples.

  19. AFFINE TRANSFORMATION IN RANDOM ITERATED FUNCTION SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    熊勇; 史定华

    2001-01-01

    Random iterated function systems (IFSs) is discussed, which is one of the methods for fractal drawing. A certain figure can be reconstructed by a random IFS. One approach is presented to determine a new random IFS, that the figure reconstructed by the new random IFS is the image of the origin figure reconstructed by old IFS under a given affine transformation. Two particular examples are used to show this approach.

  20. Integral affine Schur-Weyl reciprocity

    CERN Document Server

    Fu, Qiang

    2012-01-01

    Let ${\\boldsymbol{\\mathfrak D}_{\\vartriangle}}(n)$ be the double Ringel--Hall algebra of the cyclic quiver $\\triangle(n)$ and let $\\dot{\\boldsymbol{\\mathfrak D}_{\\vartriangle}}(n)$ be the modified quantum affine algebra of ${\\boldsymbol{\\mathfrak D}_{\\vartriangle}}(n)$. We will construct an integral form $\\dot{{\\mathfrak D}_{\\vartriangle}}(n)$ for $\\dot{\\boldsymbol{\\mathfrak D}_{\\vartriangle}}(n)$ such that the natural algebra homomorphism from $\\dot{{\\mathfrak D}_{\\vartriangle}}(n)$ to the integral affine quantum Schur algebra is surjective. Furthermore, we will use Hall algebras to construct the integral form ${\\mathcal U}_{\\mathbb Z}(\\hat{\\frak{gl}}_n)$ of the universal enveloping algebra ${\\mathcal U}(\\hat{\\frak{gl}}_n)$ of the loop algebra $\\hat{\\frak{gl}}_n=\\frak{gl}_n({\\mathbb Q})\\otimes\\mathbb Q[t,t^{-1}]$, and prove that the natural algebra homomorphism from ${\\mathcal U}_\\mathbb Z(\\hat{\\frak{gl}}_n)$ to the affine Schur algebra over $\\mathbb Z$ is surjective.

  1. Overview of affinity biosensors in food analysis.

    Science.gov (United States)

    Patel, Pradip D

    2006-01-01

    The 4 major driving forces that are expected to lead to increased use of affinity biosensors that meet crucial industrial test specifications, e.g., fast, reliable, cost-effective, and use of low-skilled personnel, are (1) strict legislative framework, e.g., recent changes proposed to the European food safety and hygiene legislation, EC No. 178/2002; (2) industrial shift from quality control to quality assurance procedures, e.g., Hazard Analysis Critical Control Point, ensuring effective positioning in the global competitive trade; (3) just-in-time production resulting in 'right' product every time; and (4) consumer demand for safe and wholesome products. The affinity biosensors field has expanded significantly over the past decade, with a projected global biosensors market growth from $6.1 billion in 2004 to $8.2 billion in 2009, representing major industrial sectors (e.g., Pharma, Medicare, and Food). This brief review is targeted to affinity biosensors developed for the food industry and includes research and development leading to biosensors for microbiological and chemical analytes of industrial concern, commercial biosensors products on the market, and examples of future prospects in this diagnostic field.

  2. On constructing purely affine theories with matter

    Science.gov (United States)

    Cervantes-Cota, Jorge L.; Liebscher, D.-E.

    2016-08-01

    We explore ways to obtain the very existence of a space-time metric from an action principle that does not refer to it a priori. Although there are reasons to believe that only a non-local theory can viably achieve this goal, we investigate here local theories that start with Schrödinger's purely affine theory (Schrödinger in Space-time structure. Cambridge UP, Cambridge, 1950), where he gave reasons to set the metric proportional to the Ricci curvature aposteriori. When we leave the context of unified field theory, and we couple the non-gravitational matter using some weak equivalence principle, we can show that the propagation of shock waves does not define a lightcone when the purely affine theory is local and avoids the explicit use of the Ricci tensor in realizing the weak equivalence principle. When the Ricci tensor is substituted for the metric, the equations seem to have only a very limited set of solutions. This backs the conviction that viable purely affine theories have to be non-local.

  3. On constructing purely affine theories with matter

    CERN Document Server

    Cervantes-Cota, Jorge L

    2016-01-01

    We explore ways to obtain the very existence of a space-time metric from an action principle that does not refer to it a priori. Although there are reasons to believe that only a non-local theory can viably achieve this goal, we investigate here local theories that start with Schroedinger's purely affine theory [21], where he gave reasons to set the metric proportional to the Ricci curvature aposteriori. When we leave the context of unified field theory, and we couple the non-gravitational matter using some weak equivalence principle, we can show that the propagation of shock waves does not define a lightcone when the purely affine theory is local and avoids the explicit use of the Ricci tensor in realizing the weak equivalence principle. When the Ricci tensor is substituted for the metric, the equations seem to have only a very limited set of solutions. This backs the conviction that viable purely affine theories have to be non-local.

  4. Programa e estratégia da revolução mexicana em Ricardo Flores Magón

    Directory of Open Access Journals (Sweden)

    Fabio Santos

    2010-12-01

    ="Subtle Emphasis" />

    No decênio anterior a explosão da Revolução Mexicana (1910, Ricardo Flores Magón (1874-1922 liderou o Partido Liberal Mexicano em uma trajetória de radicalização política e ideológica, evoluindo da denúncia de cunho jurídico dos abusos da ditadura até afirmar-se como oposição revolucionária ao Porfiriato. Constrangido ao exílio nos Estados Unidos, Ricardo planejou duas

  5. Experimental investigation of streamer affinity for dielectric surfaces

    NARCIS (Netherlands)

    Trienekens, D.J.M.; Nijdam, S.; Akkermans, G.; Plompen, I.; Christen, T.; Ebert, U.

    2015-01-01

    We have experimentally investigated the affinity of streamers for dielectric surfaces using stroboscopic imaging and stereo photography. Affinity of streamers for dielectric surfaces was found to depend on a wide set of parameters, including pressure, voltage, dielectric material and di

  6. Diversidade de abelhas visitantes das flores de Citrus em pomares de laranjeira e tangerineira Diversity of flowers visiting bees of Citrus in salinas, state of minas gerais

    Directory of Open Access Journals (Sweden)

    Eduardo Tigre do Nascimento

    2011-03-01

    Full Text Available A presença de abelhas em culturas de valor comercial, no período de florescimento, é importante não apenas para garantir a polinização cruzada, quando indispensável, mas também para incrementar a produção de frutos e sementes. Nessa perspectiva, o presente trabalho teve a finalidade de identificar as abelhas visitantes das flores em pomar de laranjeira (Citrus sinensis e tangerineira (Citrus reticulata em Salinas - MG. O trabalho foi conduzido na fazenda experimental Santa Isabel, da Escola Agrotécnica Federal de Salinas - MG, em pomares de laranjeira com as variedades, pera, baía e baianinha, e de tangerineira, variedade poncã. As coletas das abelhas visitantes das culturas da laranjeira e tangerineira foram feitas nas floradas principais, entre os meses de agosto e outubro. Foram coletadas as abelhas que visitaram as flores nos horários entre 06 h e 18 h, totalizando 52 horas na laranjeira e 50 horas na tangerineira. No pomar de laranjeira, foram coletados 5.045 espécimes com riqueza de 12 espécies, e na tangerineira, 1.428 espécimes com 20 espécies. As espécies de abelhas de maior predominância e dominância em todos os horários amostrados foram Apis mellifera e Trigona spinipes na cultura da laranjeira e A. mellifera, T. spinipes e Tetragonisca angustula na cultura da tangerineira.The presence of bees on cultures with commercial value during flowering is important to ensure the cross-pollination, when necessary, but also to increase the production of fruits and seeds. This work aimed to identify flowers' visiting bees on orange and tangerine orchards in Salinas - MG. The work was leaded on Santa Isabel experimental farm of the Federal Agro-technical School of Salinas - MG, on orange orchards (Citrus sinensis with pear, bahia and baianinha varieties in the spacing of 5,0 x 6,0, and on tangerine orchards (C. reticulate using poncã variety in the spacing of 5,0 x 5,0. The sampling of visiting bees from orange and tangerine

  7. Morphology and anatomy of flowers and seeds of Lippia alba Morfología y anatomía de las flores y semillas de pronto alivio

    Directory of Open Access Journals (Sweden)

    Sánchez Manuel Salvador

    2007-03-01

    Full Text Available For description three accesions of L. alba from Llanos Orientales and Valle (Colombia and Costa Rica (Central America were used. The inflorescences are simples and racemoses. The flowers are small, sessiles, lilac color, disposed trought of the rachis, localizated in the axillas, coupled and apposited. The flowers in primary, secondary and tertiary branches present two white sepals, pubescents with 1.5 mm of length. There is a green bract covering the sepals with a length between 3.0 and 5.0 mm. An openned flower measures up to 7.0 mm and between 3.0 and 4.0 mm of wide. They are gamopetalous, zygomorphic, pubescents, tubulars, bilabiates, with four petals, hypogynous, syncarpic gynaeceum with two carpels, upper ovary, white-green style, yellow - greenish stigma. The anthers measure 0.2 mm of length. The fruit is a diachene, with two small seeds, its fruit size is around 2.0 mm of length and 1.8 mm of wide; white, hard and dry coffee pericarp, pubescent and hard epicarp. The seed had a triangular form which measure between 0,8 mm in length and 0,3 mm wide. Keywords: Lippia alba, Verbenaceae, floral biology, seeds.En la descripción se utilizaron tres accesiones de Lippia alba provenientes de Llanos Orientales y Valle (Colombia y Costa Rica (Centro América. Las inflorescencias son espigas racemosas simples, de flores sésiles, color lila pálido y dispuestas a lo largo del raquis, localizadas en las axilas, en pares y opuestas. Las flores dispuestas en ramas principales, secundarias y terciarias presentan dos sépalos blancos, pubescentes y miden 1.5 mm de longitud. Cubriendo cada par de sépalos hay una bráctea verde, ovada y posee una longitud entre 3 y 5 mm. Una flor abierta mide hasta 7.0 mm y entre 3 y 4 mm de ancho. Son gamopétalas, zigomorfas, pubescentes, tubulares, de color lila, bilabiadas, con cuatro pétalos, hipóginas, gineceo sincárpico y bicarpelar, ovario súpero, verde blanquecino, estilo blanquecino y estigma amarillo

  8. EFEITO DO ESTÁGIO DE DESENVOLVIMENTO DAS FLORES E DA APLICAÇÃO DE FUNGICIDAS NO CONTROLE DA PODRIDÃO FLORAL DOS CITROS

    Directory of Open Access Journals (Sweden)

    ROBERTO SÉRGIO RUFFO

    2001-01-01

    Full Text Available O presente trabalho teve por objetivo determinar os melhores estágios do desenvolvimento das flores de laranja-doce para o controle da Podridão Floral dos Citros (PFC, avaliando-se diversas épocas de aplicação e doses de fungicidas. Os estudos foram realizados em pomares de laranjas-'Natal' e 'Pêra' (Citrus sinensis [L.] Osbeck, onde foram marcados aleatoriamente ramos florais pertencentes à florada temporã (janeiro de 1994, caracterizando as fases de desenvolvimento de cada botão floral. Em um primeiro ensaio, avaliou-se o controle da doença através de pulverizações manuais, onde foram aplicados os seguintes tratamentos (doses por 1 L: a testemunha; b benomyl 0,5 g, no dia de marcação dos ramos (aplicação normal; c benomyl 0,5 g, 3 a 4 dias depois da marcação (aplicação tardia; e d benomyl 0,5 g em 2 aplicações, uma na marcação dos botões e outra uma semana depois. As aplicações foram feitas com pulverizadores manuais, molhando-se apenas os ramos com flores marcados. Em um segundo ensaio, avaliou-se o controle da doença através de pulverizações tratorizadas. Na laranja-'Natal', estudaram-se os seguintes tratamentos (doses por 2.000 L: a testemunha; b benomyl 1 kg em 4/jan; c benomyl 1 kg em 4 e 11/jan; e d benomyl 1 kg em 8/jan. Na laranja-'Pêra', os seguintes tratamentos foram aplicados (doses por 2.000 L: a testemunha; b benomyl 1 kg, 4/jan; c benomyl 1 kg, 4 e 10/jan; d benomyl 1 kg + captan 3,5 kg, 4/jan; e benomyl 0,75 kg + captan 2,5 kg, 4/jan; f benomyl 1 kg + captan 2,5 kg, 4/jan; g benomyl 1 kg + captan 2,5 kg, 4/jan + benomyl 1 kg, 10/jan; h benomyl 1,5 kg, 4/jan; e i benomyl 1,5 kg, 4 e 10/jan. Avaliaram-se, em intervalos de dois dias, a freqüência e a época de ocorrência das lesões nas pétalas dos botões florais, a porcentagem de pegamento e o índice de cálices retidos de cada parcela. Pelos resultados, pôde-se concluir que o benomyl é eficiente no controle da PFC em doses de 0,5-0,75 g

  9. Actividad antiinflamatoria de flores y hojas de Caesalpinia pulcherrima L. (Swartz Anti-inflammatory activity of flowers and leaves of Caesalpinia pulcherrima L. (Swartz

    Directory of Open Access Journals (Sweden)

    Germán Eduardo Matiz

    2011-12-01

    Full Text Available Introducción: Partes aéreas de la planta Caesalpinia pulcherrima L. (Swartz han sido usadas en medicina tradicional al sur del Departamento de Cundinamarca para el tratamiento de afecciones inflamatorias. Objetivo: Evaluar la actividad antiinflamatoria de flores, hojas y frutos verdes de Caesalpinia pulcherrima para cuantificar su actividad antiinflamatoria en modelos murinos de inflamación aguda y subcrónica. Metodología: Este estudio cuantificó la actividad antiinflamatoria de diferentes extractos de tejidos aéreos de esta especie encontrada en Colombia por dos modelos de inflamación aguda, el edema auricular inducido por TPA (acetato de 12-O-tetradecanoil-forbol y el edema plantar inducido por carragenina; así como el modelo de inflamación sub-crónico de granuloma inducido por pellet de algodón. Resultados: Los extractos de flores mostraron la mayor actividad antiinflamatoria en el modelo del TPA, en tanto que las hojas fueron más efectivas en disminuir el granuloma, en el modelo del pellet de algodón. No se observó ninguna actividad antiinflamatoria de ningún extracto en el modelo de carragenina. Los frutos verdes no mostraron actividad en ningún modelo. Conclusión: Los resultados demostraron la efectividad que el uso etnobotánico le atribuye a esta planta. Los extractos activos obtenidos mostraron el potencial uso de esta planta en la fabricación fitoterapéuticos efectivos. Salud UIS 2011; 43 (3: 281-287Introduction: Aerial parts of Caesalpinia pulcherrima L. (Swartz have been used in traditional medicine in southern Cundinamarca Department for the treatment of inflammatory diseases. Objective: Evaluate the antiinflammatory activity of flowers, leaves and green fruits of the plant to quantify inflammatory activity of acute and subchronic murine inflammation models. Methodology: This study quantified the anti-inflammatory activity of different extracts of aerial tissues of this species for two models of acute

  10. Fractal-Based Exponential Distribution of Urban Density and Self-Affine Fractal Forms of Cities

    CERN Document Server

    Chen, Yanguang

    2016-01-01

    Urban population density always follows the exponential distribution and can be described with Clark's model. Because of this, the spatial distribution of urban population used to be regarded as non-fractal pattern. However, Clark's model differs from the exponential function in mathematics because that urban population is distributed on the fractal support of landform and land-use form. By using mathematical transform and empirical evidence, we argue that there are self-affine scaling relations and local power laws behind the exponential distribution of urban density. The scale parameter of Clark's model indicating the characteristic radius of cities is not a real constant, but depends on the urban field we defined. So the exponential model suggests local fractal structure with two kinds of fractal parameters. The parameters can be used to characterize urban space filling, spatial correlation, self-affine properties, and self-organized evolution. The case study of the city of Hangzhou, China, is employed to ...

  11. Glycation of the high affinity NGF-receptor and RAGE leads to reduced ligand affinity.

    Science.gov (United States)

    Bennmann, Dorit; Kannicht, Christoph; Fisseau, Claudine; Jacobs, Kathleen; Navarette-Santos, Alexander; Hofmann, Britt; Horstkorte, Rüdiger

    2015-09-01

    AGEs are posttranslational modifications generated by irreversible non-enzymatic crosslinking reactions between sugars and proteins - a reaction referred to as glycation. Glycation, a feature of ageing, can lead to non-degradable and less functional proteins and enzymes and can additionally induce inflammation and further pathophysiological processes such as neurodegeneration. In this study we investigated the influence of glycation on the high affinity NGF-receptor TrkA and the AGE-receptor RAGE. We quantified the binding affinity of the TrkA-receptor and RAGE to their ligands by surface plasmon resonance (SPR) and compared these to the binding affinity after glycation. At the same time, we established a glycation procedure using SPR. We found that glycation of TrkA reduced the affinity to NGF by a factor of three, which could be shown to lead to a reduction of NGF-dependent neurite outgrowth in PC12 cells. Glycation of RAGE reduced binding affinity of AGEs by 10-fold.

  12. Affine Structures on a Ringed Space and Schemes

    Institute of Scientific and Technical Information of China (English)

    Fengwen AN

    2011-01-01

    The author first introduces the notion of affine structures on a ringed space and then obtains several related properties. Affine structures on a ringed space, arising from complex analytical spaces of algebraic schenes, behave like differential structures on a smooth nanifold.As one does for differential manifolds, pseudogroups of affine transformations are used to define affine atlases on a ringed space. An atlas on a space is said to be an affine structure if it is maximal. An affine structure is said to be admissible if there is a sheaf on the underlying space such that they are coincide on all affine charts, which are in deed affine open sets of a scheme. In a rigour manner, a scheme is defined to be a ringed space with a specified affine structure if the affine structures make a contribution to the cases such as analytical spaces of algebraic schemes. Particularly, by the whole of affine structures on a pace, two necessary and sufficient conditions, that two spaces are homeomorphic and that two schemes are isomorphic, coming from the main theorems of the paper, are obtained respectively. A conclusion is drawn that the whole of affine structures on a space and a scheme, as local data, encode and reflect the global properties of the space and the scheme,respectively.

  13. Spatial model of affinity maturation in germinal centers

    NARCIS (Netherlands)

    Kesmir, C.; Boer, R.J. de

    2003-01-01

    Affinity maturation of humoral responses to T-cell-dependent antigens occurs in germinal centers (GC). In GCs antigen-specific B cells undergo rounds of somatic mutations that alter their affinity. High-affinity mutants take over GCs very soon after they appear; the replacement rate is as high as 4

  14. Duals of Affine Grassmann Codes and Their Relatives

    DEFF Research Database (Denmark)

    Beelen, P.; Ghorpade, S. R.; Hoholdt, T.

    2012-01-01

    Affine Grassmann codes are a variant of generalized Reed-Muller codes and are closely related to Grassmann codes. These codes were introduced in a recent work by Beelen Here, we consider, more generally, affine Grassmann codes of a given level. We explicitly determine the dual of an affine Grassm...

  15. Aplicación de compost de residuos de flores en suelos ácidos cultivados con maíz (Zea mays

    Directory of Open Access Journals (Sweden)

    Martha Constanza Daza Torres

    2014-01-01

    Full Text Available Los suelos ácidos tropicales se caracterizan por su baja fertilidad y presencia de minerales fijadores que limitan la disponibilidad de nutrientes. El presente estudio fue llevado a cabo con el propósito de estudiar la aplicación de compost de residuos de flores en propiedades químicas de un Oxisol proveniente de los Llanos Orientales colombianos y en variables agronómicas de maíz (Zea mays. El experimento consistió en siete tratamientos: testigo, compost, cal, fertilizante inorgánico, compost + cal, compost + fertilizante inorgánico y compost + fertilizante inorgánico + cal con tres repeticiones en un diseño de bloques completos al azar donde las propiedades químicas del suelo evaluadas fueron pH, acidez intercambiable, materia orgánica, fósforo disponible y las relaciones C/N y C/P al inicio, a la quinta y décima semana después de la siembra. También algunas propiedades agronómicas del cultivo fueron evaluadas como altura de planta, peso de masa seca y contenido foliar de nutrientes. Los resultados mostraron que al combinar el compost con el fertilizante inorgánico se obtuvieron mejores condiciones en el suelo para el desarrollo del maíz aunque a las diez semanas el suelo tendió a su estado inicial, indicando la necesidad de aplicaciones periódicas de enmiendas para sostener su productividad.

  16. Triagem fitoquímica e avaliação da atividade antibacteriana de extratos das flores de Sambucus nigra L. (Caprifoliaceae

    Directory of Open Access Journals (Sweden)

    A.K. MATTE

    2015-01-01

    Full Text Available RESUMO O presente trabalho teve como objetivo realizar a triagem fitoquímica e avaliar a atividade antibacteriana de extratos das flores de Sambucus nigraL. Os extratos; aquoso (10 %, etanólico (5 % e Acetato de etila (5 % foram submetidos a testes colorimétricos para triagem fitoquímica e a avaliação da atividade antibacteriana foi realizada pelo método de disco-difusão em ágar. Os resultados mostraram que nas concentrações de 6 e 12 mg o extrato aquoso apresentou halos significativos de inibição para Staphylococcus aureus, Pseudomonas aeruginosa e Streptococcus pyogenes, porém, quando comparado aos medicamentos usados como referência a atividade não foi satisfatória, e, ainda, evidenciou a ausência de inibição para todas as cepas testadas com o aumento da concentração para 18 e 24 mg. A análise da triagem fitoquímica evidenciou a presença de flavonoides com intensa reação de cor no extrato aquoso e etanólico, e de fraca intensidade no extrato acetato de etila. Nos mesmos extratos, pelos testes realizados, não foram detectados taninos, saponinas, antraquinonas e alcaloides. Concluiu-se que o extrato aquoso apresentou melhor efeito inibitório para Staphylococcus aureus, Pseudomonas aeruginosa e Streptococcus pyogenes, porém insuficiente para promover a inativação eficiente quando comparado aos controles.

  17. Alteraciones citogenéticas en trabajadoras con riesgo ocupacional de exposición a plaguicidas en cultivos de flores en Bogotá.

    Directory of Open Access Journals (Sweden)

    Marcela Varona

    2003-06-01

    Full Text Available Se determinó la frecuencia de alteraciones citogenéticas (micronúcleos y aberraciones cromosómicas, deficiencias en la reparación del ADN y actividad de la acetilcolinesterasa como biomarcadores de exposición a plaguicidas organofosforados y carbamatos en trabajadoras de cultivos de flores en Bogotá. Se realizó un estudio descriptivo en 31 trabajadoras con riesgo ocupacional de exposición a plaguicidas y 30 sin riesgo; la información se obtuvo por medio de una entrevista. Se emplearon como pruebas citogenéticas estándar la frecuencia de aberraciones cromosómicas y de micronúcleos; la prueba de reto (challenge assay se utilizó para determinar la respuesta a los rayos gamma y como indicador de deficiencias en la reparación del ADN. Los datos se analizaron por porcentaje de células aberrantes, frecuencia de aberraciones cromosómicas y rompimiento cromatídico en 100 células en metafase analizadas en cada trabajadora. En los ensayos citogenéticos, se encontró que el grupo expuesto presentó frecuencias mayores de células con aberraciones cromosómicas y micronúcleos que el grupo no expuesto, con diferencias significativas (p=0,02; sin embargo, con la prueba de reto, la diferencia no fue significativa (p>0,1. Estos hallazgos requieren ser confirmados por estudios de tipo analítico que involucren exámenes clínicos; además, es necesario un mayor número de biomarcadores para la monitorización de trabajadores expuestos a plaguicidas en cualquier situación.

  18. Avaliação da atividade antibacteriana de extratos etanólico e de ciclohexano a partir das flores de camomila (Matricaria chamomilla L.

    Directory of Open Access Journals (Sweden)

    A.F. Carvalho

    2014-09-01

    Full Text Available Devido à crescente seleção de microrganismos resistentes aos antimicrobianos atuais, tem-se valorizado a busca por alternativas naturais. O presente estudo teve por objetivo avaliar a atividade antibacteriana de extratos etanólico e de ciclohexano de flores de camomila, espécie vegetal de uso antigo pela medicina tradicional, frente às bactérias ATCC Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli e Salmonella enterica subsp. enterica sorovar Typhimurium pelas técnicas de difusão em ágar e diluição em caldo. Foi observada inibição do crescimento de P. aeruginosa frente ao extrato etanólico bruto (1g/mL na técnica de diluição em caldo, e confirmada pela técnica de difusão em ágar (halo de inibição de 10 mm de diâmetro. Para as demais bactérias testadas, os extratos e suas diluições não apresentaram efeito bacteriostático em nenhuma das técnicas. Pode-se concluir que o extrato etanólico bruto da camomila apresentou atividade antibacteriana frente à P. aeruginosa, porém não foi eficaz frente à S. aureus, E. coli e Salmonella enterica subsp. enterica sorovar Typhimurium. Portanto, são necessários novos estudos com diferentes linhagens de microrganismos, com o intuito de corroborar e assegurar os resultados apresentados, para definir o potencial antimicrobiano do extrato da camomila.

  19. A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination.

    Science.gov (United States)

    Baumgartner, Christina K; Yagita, Hideo; Malherbe, Laurent P

    2012-09-01

    Diverse Ag-specific memory TCR repertoires are essential for protection against pathogens. Subunit vaccines that combine peptide or protein Ags with TLR agonists are very potent at inducing T cell immune responses, but their capacity to elicit stable and diverse memory CD4 T cell repertoires has not been evaluated. In this study, we examined the evolution of a complex Ag-specific population during the transition from primary effectors to memory T cells after peptide or protein vaccination. Both vaccination regimens induced equally diverse effector CD4 TCR repertoires, but peptide vaccines skewed the memory CD4 TCR repertoire toward high-affinity clonotypes whereas protein vaccines maintained low-affinity clonotypes in the memory compartment. CD27-mediated signaling was essential for the maintenance of low-affinity clonotypes after protein vaccination but was not sufficient to promote their survival following peptide vaccination. The rapid culling of the TCR repertoire in peptide-immunized mice coincided with a prolonged proliferation phase during which low-affinity clonotypes disappeared despite exhibiting no sign of enhanced apoptosis. Our study reveals a novel affinity threshold for memory CD4 T cell differentiation following vaccination and suggests a role for nonapoptotic cell death in the regulation of CD4 T cell clonal selection.

  20. Radiosynthesis and Evaluation of [(11)C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites

    DEFF Research Database (Denmark)

    Jensen, Claus H; Hansen, Hanne D; Bay, Tina

    2017-01-01

    the (11)C-labeling and subsequent evaluation of [(11)C]HOCPCA in a domestic pig, as a PET-radioligand for visualization of the high-affinity GHB binding sites in the live pig brain. To investigate the regional binding of HOCPCA in pig brain prior to in vivo PET studies, in vitro quantitative......γ-Hydroxybutyric acid (GHB) is an endogenous neuroactive substance and proposed neurotransmitter with affinity for both low- and high-affinity binding sites. A radioligand with high and specific affinity toward the high-affinity GHB binding site would be a unique tool toward a more complete...... understanding of this population of binding sites. With its high specific affinity and monocarboxylate transporter (MCT1) mediated transport across the blood-brain barrier in pharmacological doses, 3-hydroxycyclopent-1-enecarboxylic acid (HOCPCA) seems like a suitable PET radiotracer candidate. Here, we report...

  1. Analysis of affinely equivalent Boolean functions

    Institute of Scientific and Technical Information of China (English)

    MENG QingShu; ZHANG HuanGuo; YANG Min; WANG ZhangYi

    2007-01-01

    By some basic transforms and invariant theory, we give two results: 1) an algorithm,which can be used to judge if two Boolean functions are affinely equivalent and to obtain the equivalence relationship if they are equivalent. This is useful in studying Boolean functions and in engineering. For example, we classify all 8-variable homogeneous bent functions of degree 3 into two classes; 2) Reed-Muller codes R(4,6)/R(1,6), R(3,7)/R(1,7) are classified efficiently.

  2. Affine Coherent States in Quantum Cosmology

    CERN Document Server

    Malkiewicz, Przemyslaw

    2015-01-01

    A brief summary of the application of coherent states in the examination of quantum dynamics of cosmological models is given. We discuss quantization maps, phase space probability distributions and semiclassical phase spaces. The implementation of coherent states based on the affine group resolves the hardest singularities, renders self-adjoint Hamiltonians without boundary conditions and provides a completely consistent semi-classical description of the involved quantum dynamics. We consider three examples: the closed Friedmann model, the anisotropic Bianchi Type I model and the deep quantum domain of the Bianchi Type IX model.

  3. Latest European coelacanth shows Gondwanan affinities.

    Science.gov (United States)

    Cavin, Lionel; Forey, Peter L; Buffetaut, Eric; Tong, Haiyan

    2005-06-22

    The last European fossil occurrence of a coelacanth is from the Mid-Cretaceous of the English Chalk (Turonian, 90 million years ago). Here, we report the discovery of a coelacanth from Late Cretaceous non-marine rocks in southern France. It consists of a left angular bone showing structures that imply close phylogenetic affinities with some extinct Mawsoniidae. The closest relatives are otherwise known from Cretaceous continental deposits of southern continents and suggest that the dispersal of freshwater organisms from Africa to Europe occurred in the Late Cretaceous.

  4. Metric-affine gravitation theory and superpotentials

    Energy Technology Data Exchange (ETDEWEB)

    Giachetta, G.; Mangiarotti, L.; Saltarelli, A. [Camerino, Univ. (Italy). Dipt. di Matematica e Fisica

    1997-05-01

    They consider a metric-affine theory of gravity in which the dynamical fields are the Lorentzian metrics and the non-symmetric linear connections on the worked manifold X. Working with a Lagrangian density which is invariant under general covariant transformations and using standard tools of the calculus of variations, they study the corresponding currents. They find that the superpotential takes a nice form involving the torsion of the linear connection in a simple way and generalizing the well-known Komar superpotential. A feature of our approach is the use of the Poincare`-Cartan form in relation to the first variational formula of the calculus of variations.

  5. Affinity chromatography with an immobilized RNA enzyme.

    OpenAIRE

    Vioque, A; Altman, S

    1986-01-01

    M1 RNA, the catalytic subunit of Escherichia coli RNase P, has been covalently linked at its 3' terminus to agarose beads. Unlike M1 RNA, which is active in solution in the absence of the protein component (C5) of RNase P, the RNA linked to the beads is active only in the presence of C5 protein. Affinity chromatography of crude extracts of E. coli on a column prepared from the beads to which the RNA has been crosslinked results in the purification of C5 protein in a single step. The protein h...

  6. Affine Fullerene C60 in a GS-Quasigroup

    Directory of Open Access Journals (Sweden)

    Vladimir Volenec

    2014-01-01

    Full Text Available It will be shown that the affine fullerene C60, which is defined as an affine image of buckminsterfullerene C60, can be obtained only by means of the golden section. The concept of the affine fullerene C60 will be constructed in a general GS-quasigroup using the statements about the relationships between affine regular pentagons and affine regular hexagons. The geometrical interpretation of all discovered relations in a general GS-quasigroup will be given in the GS-quasigroup C(1/2(1+5.

  7. Affinity filtration coupled with capillary-based affinity purification for the isolation of protein complexes.

    Science.gov (United States)

    Qureshi, M S; Sheikh, Q I; Hill, R; Brown, P E; Dickman, M J; Tzokov, S B; Rice, D W; Gjerde, D T; Hornby, D P

    2013-08-01

    The isolation of complex macromolecular assemblies at the concentrations required for structural analysis represents a major experimental challenge. Here we present a method that combines the genetic power of site-specific recombination in order to selectively "tag" one or more components of a protein complex with affinity-based rapid filtration and a final step of capillary-based enrichment. This modified form of tandem affinity purification produces highly purified protein complexes at high concentrations in a highly efficient manner. The application of the method is demonstrated for the yeast Arp2/3 heptameric protein complex involved in mediating reorganization of the actin cytoskeleton.

  8. Dendrobium 'Brazilian Fire 101' - New option of color of flowers for the orchid market Dendrobium 'Brazilian Fire 101' - Nova opção de coloração de flores para o mercado de orquídeas

    Directory of Open Access Journals (Sweden)

    Jean C Cardoso

    2012-09-01

    Full Text Available Establishment of germplasm banks of ornamental species, together with breeding programs is fundamental for the growth of competitive cultivars of flowers that are the same or better quality than those developed in other countries. Around 100 progenies from a crossing between the cultivars Dendrobium 'Tong Chai Gold' and Dendrobium 'Black Jack' were obtained, from 50 plants which were selected and grown in pots in greenhouse conditions to evaluate the blooming stage and to select the progenies. Selection of vigorous growing plants and without disease symptoms were made in the period of cultivation. Also, there were evaluated the growing characteristics, rooting, early blooming, as well as the color, number and size of flowers in the first and second blooming. Six progenies with superior characteristics were chosen, from which Dendrobium 'Brazilian Fire 101' was obtained. This cultivar shows fast growth, good rooting, early flowering and high quality flowers, with predominantly yellow color, showing the ribs, the center of flowers and lip with red color. The durability of the flowers was 45-60 days after anthesis.O estabelecimento de bancos de germoplasma de espécies ornamentais, consorciado a programas de melhoramento genético é fundamental para a produção de cultivares de flores competitivas em meio àquelas desenvolvidas no exterior. Foram obtidas 100 progênies provenientes de um cruzamento entre as cultivares Dendrobium 'Tong Chai Gold' e Dendrobium 'Black Jack', das quais 50 foram selecionadas e cultivadas em vaso e condições de estufa até o momento da floração e seleção de progênies. As seleções de plantas com crescimento vigoroso e sem sintomas de doenças foram realizadas ao longo do tempo de cultivo. Nessas, também foram avaliadas as características de crescimento, enraizamento, floração precoce, além de coloração, número e tamanho de flores na primeira e segunda floração. Foram escolhidas seis progênies com

  9. Extraction of haemoglobin from human blood by affinity precipitation using a haptoglobin-based stimuli-responsive affinity macroligand.

    Science.gov (United States)

    Stocker-Majd, Gisela; Hilbrig, Frank; Freitag, Ruth

    2008-06-13

    Affinity precipitation was compared to affinity chromatography and batch adsorption as the final purification step in a protocol for the isolation of haemoglobin from human blood. Haptoglobin was the affinity ligand. The first steps on the process were realized by traditional methods (lyses of red blood cells followed by ammonium sulphate precipitation). For affinity chromatography (and batch adsorption) the ligand was linked to Sepharose, for affinity precipitation to a thermoresponsive polymer, namely poly(N-isopropylacrylamide). Five haptoglobin-poly(N-isopropylacrylamide) bioconjugates (affinity macroligands) were constructed with different polymer: haptoglobin-coupling ratios. Conjugation of haptoglobin to the soluble poly(N-isopropylacrylamide) apparently does not change the interaction thermodynamics with haemoglobin, as the haemoglobin binding constants calculated by a Scatchard analysis for the affinity macroligand were of the same order of magnitude as those described in the literature for the haemoglobin-haptoglobin complex in solution. Two elution protocols were used for haemoglobin release from the various affinity materials, one at pH 2, the other with 5 M urea at pH 11. Both affinity chromatography and affinity precipitation yielded a pure haemoglobin of high quality. Compared to the affinity chromatography, affinity precipitation showed a significantly higher ligand efficiency (ratio of the experimental capacity to the theoretical one). The method thus makes better use of the expensive affinity ligands. As affinity precipitation only requires small temperature changes to bring about precipitation/redissolution of the affinity complexes and a centrifugation step for recovery of the precipitate, the method in addition has advantages in term of scalability and simplicity.

  10. Affine conformal vectors in space-time

    Science.gov (United States)

    Coley, A. A.; Tupper, B. O. J.

    1992-05-01

    All space-times admitting a proper affine conformal vector (ACV) are found. By using a theorem of Hall and da Costa, it is shown that such space-times either (i) admit a covariantly constant vector (timelike, spacelike, or null) and the ACV is the sum of a proper affine vector and a conformal Killing vector or (ii) the space-time is 2+2 decomposable, in which case it is shown that no ACV can exist (unless the space-time decomposes further). Furthermore, it is proved that all space-times admitting an ACV and a null covariantly constant vector (which are necessarily generalized pp-wave space-times) must have Ricci tensor of Segré type {2,(1,1)}. It follows that, among space-times admitting proper ACV, the Einstein static universe is the only perfect fluid space-time, there are no non-null Einstein-Maxwell space-times, and only the pp-wave space-times are representative of null Einstein-Maxwell solutions. Otherwise, the space-times can represent anisotropic fluids and viscous heat-conducting fluids, but only with restricted equations of state in each case.

  11. Cyclage, catabolism, and the affine Hecke algebra

    CERN Document Server

    Blasiak, Jonah

    2010-01-01

    We identify a subalgebra \\pH_n of the extended affine Hecke algebra \\eH_n of type A. The subalgebra \\pH_n is a \\u-analogue of the monoid algebra of \\S_n \\ltimes \\ZZ_{\\geq 0}^n and inherits a canonical basis from that of \\eH_n. We show that its left cells are naturally labeled by tableaux filled with positive integer entries having distinct residues mod n, which we term \\emph{positive affine tableaux} (PAT). We then exhibit a cellular subquotient \\R_{1^n} of \\pH_n that is a \\u-analogue of the ring of coinvariants \\CC[y_1,...,y_n]/(e_1,...,e_n) with left cells labeled by PAT that are essentially standard Young tableaux with cocharge labels. Multiplying canonical basis elements by a certain element \\pi \\in \\pH_n corresponds to rotations of words, and on cells corresponds to cocyclage. We further show that \\R_{1^n} has cellular quotients \\R_\\lambda that are \\u-analogues of the Garsia-Procesi modules R_\\lambda with left cells labeled by (a PAT version of) the \\lambda-catabolizable tableaux. We give a conjectural d...

  12. Spherical functions on affine Lie groups

    CERN Document Server

    Etingof, P; Kirillov, A A; Pavel Etingof; Igor Frenkel; Alexander Kirillov Jr

    1994-01-01

    We show that the space of holomorphic functions of a fixed degree on an affine Lie group which take values in a finite-dimensional representation of this group and are equivariant with respect to (twisted) conjugacy coin- cides with the space of conformal blocks of the Wess-Zumino-Witten conformal field theory on an elliptic curve with punctures, or, equivalently,with the space of states of the Chern-Simons topological field theory in genus 1. This provides a group-theoretic realization of the Segal modular functor for elliptic curves. We also show that the the radial part of the second order Laplace operator on an affine Lie group acting in the space of equivariant functions coincides with the operator defining the Knizhnik-Zamolodchikov connection on conformal blocks on elliptic curves, and its eigenfunctions coincide with the correlation functions of conformal blocks. At the critical value of the degree (minus the dual Coxeter number of the underlying simple Lie algebra) there exist higher order Laplace op...

  13. Affine Mirkovi\\'c-Vilonen polytopes

    CERN Document Server

    Baumann, Pierre; Tingley, Peter

    2011-01-01

    Each integrable lowest weight representation of a symmetrizable Kac-Moody Lie algebra g has a crystal in the sense of Kashiwara, which describes its combinatorial properties. For a given g, there is a limit crystal, usually denoted by B(-\\infty), which contains all the other crystals. When g is finite dimensional, a convex polytope, called the Mirkovi\\'c-Vilonen polytope, can be associated to each element in B(-\\infty). This polytope sits in the dual space of a Cartan subalgebra of g, and its edges are parallel to the roots of g. In this paper, we generalize this construction to the case where g is a symmetric affine Kac-Moody algebra. The datum of the polytope must however be complemented by partitions attached to the edges parallel to the imaginary root \\delta. We prove that these decorated polytopes are characterized by conditions on their normal fans and on their 2-faces. In addition, we discuss how our polytopes provide an analog of the notion of Lusztig datum for affine Kac-Moody algebras. Our main tool...

  14. Affinity Crystallography: A New Approach to Extracting High-Affinity Enzyme Inhibitors from Natural Extracts.

    Science.gov (United States)

    Aguda, Adeleke H; Lavallee, Vincent; Cheng, Ping; Bott, Tina M; Meimetis, Labros G; Law, Simon; Nguyen, Nham T; Williams, David E; Kaleta, Jadwiga; Villanueva, Ivan; Davies, Julian; Andersen, Raymond J; Brayer, Gary D; Brömme, Dieter

    2016-08-26

    Natural products are an important source of novel drug scaffolds. The highly variable and unpredictable timelines associated with isolating novel compounds and elucidating their structures have led to the demise of exploring natural product extract libraries in drug discovery programs. Here we introduce affinity crystallography as a new methodology that significantly shortens the time of the hit to active structure cycle in bioactive natural product discovery research. This affinity crystallography approach is illustrated by using semipure fractions of an actinomycetes culture extract to isolate and identify a cathepsin K inhibitor and to compare the outcome with the traditional assay-guided purification/structural analysis approach. The traditional approach resulted in the identification of the known inhibitor antipain (1) and its new but lower potency dehydration product 2, while the affinity crystallography approach led to the identification of a new high-affinity inhibitor named lichostatinal (3). The structure and potency of lichostatinal (3) was verified by total synthesis and kinetic characterization. To the best of our knowledge, this is the first example of isolating and characterizing a potent enzyme inhibitor from a partially purified crude natural product extract using a protein crystallographic approach.

  15. Development of translating ribosome affinity purification for zebrafish.

    Science.gov (United States)

    Tryon, Robert C; Pisat, Nilambari; Johnson, Stephen L; Dougherty, Joseph D

    2013-03-01

    The regulation of transcription and translation by specific cell types is essential to generate the cellular diversity that typifies complex multicellular organisms. Tagging and purification of ribosomal proteins has been shown to be an innovative and effective means of characterizing the ribosome bound transcriptome of highly specific cell populations in vivo. To test the feasibility of using translating ribosome affinity purification (TRAP) in zebrafish, we have generated both a ubiquitous TRAP line and a melanocyte-specific TRAP line using the native zebrafish rpl10a ribosomal protein. We have demonstrated the capacity to capture mRNA transcripts bound to ribosomes, and confirmed the expected enrichment of melanocyte specific genes and depletion of non-melanocyte genes when expressing the TRAP construct with a cell specific promoter. We have also generated a generic EGFP-rpl10a Tol2 plasmid construct (Tol2-zTRAP) that can be readily modified to target any additional cell populations with characterized promoters in zebrafish. Copyright © 2012 Wiley Periodicals, Inc.

  16. Determinación de razas fisiológicas de Fusariumoxysporumf.sp. Dianthien suelos cultivados y en variedades de clavel en la finca "flores las palmas".

    Directory of Open Access Journals (Sweden)

    Benavides Joaquín L.

    1995-06-01

    Full Text Available

     

    EI problema fitosanitario más Limitante del cultivo del clavel en Colombia es el marchitamiento vascular ocasionado por Fusarium oxysporum f.sp. dianthi con pérdidas económicas muy importantes. EI objetivo del trabajo fue la determinación de las razas fisiológicas del patógeno en la línea "Flores Las Palmas·, localizada en el Municipio de Tocancipá, Cundinamarca, a partir de muestras de plantas de clavel afectadas y de suelo. La investigación consistió en la obtención de 50 aislamientos del hongo a partir de plantas afectadas por la enfermedad y de 50 alistamientos de suelo, los cuales se inocularon en las variedades diferenciales de clavel lbiza, Taiga, Raggio di Sole, Pink Calypso, Niki y San Remo. Los resultados mostraron que 41

    (82% de los 50 aislamientos del hongo obtenidos de plantas enfermas de clavel estándar se clasificaron como raza 2 del patógeno, cinco aislamientos (10% se caracterizaron como de baja patogenicidad, por l0 cual no fue posible determinar la raza a la cual pertenecen y cuatro aislamientos (8% se caracterizaron por no ser patogénicos en plantas de clavel. De los 50 aislamientos del hongo obtenidos a partir de muestras de suelo, solamente uno de ellos (2% Jue patogénico en plantas de clavel y se clasifico como raza 2, siendo los demás aislamientos no patogénicos en plantas de clavel.

  17. Manejo da queima das flores e da podridão-parda do pessegueiro cultivado em sistema orgânico

    Directory of Open Access Journals (Sweden)

    Genuino Negri

    2011-10-01

    Full Text Available O presente trabalho objetivou avaliar o uso de fosfitos, iodo, calda sulfocálcica e Trichothecium roseum no manejo da Queima das flores e da Podridão-Parda do pessegueiro, doenças causadas por Monilinia fructicola, nas cultivares Granada e Chimarrita, em cultivo orgânico. Os tratamentos foram: 1 calda sulfocálcica + iodo (aplicada na floração e na pré-colheita; 2 alternância entre calda sulfocálcica + iodo, fosfito de CaB e T. roseum (aplicados na floração e Fosfito de K e T. roseum (aplicados na pré-colheita; 3 T. roseum (aplicado na floração e na pré-colheita; 4 testemunha. Os tratamentos foram paralisados uma semana antes do início da colheita. A doença foi quantificada pela incidência da doença nas fases de floração, de frutos verdes, de colheita e de pós-colheita. A incidência da doença na testemunha, na fase de floração, variou de 22 a 72%; nos frutos verdes, de 19 a 30%, e na colheita, de 18 a 61%. Todos os tratamentos reduziram a doença nas fases de floração e de frutos verdes, em ambas as cultivares, na ordem de 49 a 73% na floração e de 57 a 84% na fase de frutos verdes em relação à testemunha. Resultados significativos foram obtidos também em pós-colheita, na cultivar Granada, com reduções da doença em 54% no tratamento 1, e 30% no tratamento 2. Nenhum dos tratamentos foi eficiente na redução da incidência da doença na colheita.

  18. Affine connection form of Regge calculus

    CERN Document Server

    Khatsymovsky, V M

    2015-01-01

    Regge action is represented analogously to how the Palatini action for general relativity (GR) as some functional of the metric and a general connection as independent variables represents the Einstein-Hilbert action. The piecewise flat (or simplicial) spacetime of Regge calculus is equipped with some world coordinates and some piecewise affine metric which is completely defined by the set of edge lengths and the world coordinates of the vertices. The conjugate variables are the general nondegenerate matrices on the 3-simplices which play a role of a general discrete connection. Our previous result on some representation of the Regge calculus action in terms of the local Euclidean (Minkowsky) frame vectors and orthogonal connection matrices as independent variables is somewhat modified for the considered case of the general linear group GL(4,R) of the connection matrices. As a result, we have some action invariant w. r. t. arbitrary change of coordinates of the vertices (and related GL(4,R) transformations in...

  19. Gravitational Goldstone fields from affine gauge theory

    CERN Document Server

    Tresguerres, R

    2000-01-01

    In order to facilitate the application of standard renormalization techniques, gravitation should be decribed, if possible, in pure connection formalism, as a Yang-Mills theory of a certain spacetime group, say the Poincare or the affine group. This embodies the translational as well as the linear connection. However, the coframe is not the standard Yang-Mills type gauge field of the translations, since it lacks the inhomogeneous gradient term in the gauge transformations. By explicitly restoring the "hidden" piece responsible for this behavior within the framework of nonlinear realizations, the usual geometrical interpretation of the dynamical theory becomes possible, and in addition one can avoid the metric or coframe degeneracy which would otherwise interfere with the integrations within the path integral. We claim that nonlinear realizations provide a general mathematical scheme clarifying the foundations of gauge theories of spacetime symmetries. When applied to construct the Yang-Mills theory of the aff...

  20. Automatic gesture analysis using constant affine velocity.

    Science.gov (United States)

    Cifuentes, Jenny; Boulanger, Pierre; Pham, Minh Tu; Moreau, Richard; Prieto, Flavio

    2014-01-01

    Hand human gesture recognition has been an important research topic widely studied around the world, as this field offers the ability to identify, recognize, and analyze human gestures in order to control devices or to interact with computer interfaces. In particular, in medical training, this approach is an important tool that can be used to obtain an objective evaluation of a procedure performance. In this paper, some obstetrical gestures, acquired by a forceps, were studied with the hypothesis that, as the scribbling and drawing movements, they obey the one-sixth power law, an empirical relationship which connects path curvature, torsion, and euclidean velocity. Our results show that obstetrical gestures have a constant affine velocity, which is different for each type of gesture and based on this idea this quantity is proposed as an appropriate classification feature in the hand human gesture recognition field.

  1. Self-affinity and nonextensivity of sunspots

    Energy Technology Data Exchange (ETDEWEB)

    Moret, M.A., E-mail: mamoret@gmail.com [Programa de Modelagem Computacional, SENAI, Cimatec, Av. Orlando Gomes, 1845, Piatã, 41650-010 Salvador, Bahia (Brazil); UNEB, Rua Silveira Martins, 2555, Cabula, 41150-000 Salvador, Bahia (Brazil)

    2014-01-24

    In this paper we study the time series of sunspots by using two different approaches, analyzing its self-affine behavior and studying its distribution. The long-range correlation exponent α has been calculated via Detrended Fluctuation Analysis and the power law vanishes to values greater than 11 years. On the other hand, the distribution of the sunspots obeys a q-exponential decay that suggests a non-extensive behavior. This observed characteristic seems to take an alternative interpretation of the sunspots dynamics. The present findings suggest us to propose a dynamic model of sunspots formation based on a nonlinear Fokker–Planck equation. Therefore its dynamic process follows the generalized thermostatistical formalism.

  2. Affine and Projective Tree Metric Theorems

    CERN Document Server

    Harel, Matan; Pachter, Lior

    2011-01-01

    The tree metric theorem provides a combinatorial four point condition that characterizes dissimilarity maps derived from pairwise compatible split systems. A similar (but weaker) four point condition characterizes dissimilarity maps derived from circular split systems (Kalmanson metrics). The tree metric theorem was first discovered in the context of phylogenetics and forms the basis of many tree reconstruction algorithms, whereas Kalmanson metrics were first considered by computer scientists, and are notable in that they are a non-trivial class of metrics for which the traveling salesman problem is tractable. We present a unifying framework for these theorems based on combinatorial structures that are used for graph planarity testing. These are (projective) PC-trees, and their affine analogs, PQ-trees. In the projective case, we generalize a number of concepts from clustering theory, including hierarchies, pyramids, ultrametrics and Robinsonian matrices, and the theorems that relate them. As with tree metric...

  3. Affine trajectory correction for nonholonomic mobile robots

    CERN Document Server

    Pham, Quang-Cuong

    2011-01-01

    Planning trajectories for nonholonomic systems is difficult and computationally expensive. When facing unexpected events, it may therefore be preferable to deform in some way the initially planned trajectory rather than to re-plan entirely a new one. We suggest here a method based on affine transformations to make such deformations. This method is exact and fast: the deformations and the resulting trajectories can be computed algebraically, in one step, and without any trajectory re-integration. To demonstrate the possibilities offered by this new method, we use it to derive position correction, orientation correction, obstacle avoidance and feedback control algorithms for the general class of planar wheeled robots and for a tridimensional underwater vehicle.

  4. Dynamic friction of self-affine surfaces

    Science.gov (United States)

    Schmittbuhl, Jean; Vilotte, Jean-Pierre; Roux, Stéphane

    1994-02-01

    We investigate the velocity dependence of the friction between two rigid blocks limited by a self-affine surface such as the one generated by a crack. The upper solid is subjected either to gravity or to an external elastic stiffness, and is driven horizontally at constant velocity, V, while the lower solid is fixed. For low velocities, the apparent friction coefficient is constant. For high velocities, the apparent friction is shown to display a velocity weakening. The weakening can be related to the variation of the mean contact time due to the occurrence of jumps during the motions. The cross-over between these two regimes corresponds to a characteristic velocity which depends on the geometry of the surfaces and on the mean normal force. In the case of simple gravity loading, the velocity dependence of the apparent friction at high velocities is proportional to 1/V^2 where V is the imposed tangential velocity. In the case of external elastic stiffness, two velocity weakening regimes can be identified, the first is identical to the gravity case with a 1/V^2 dependence, the second appears at higher velocities and is characterized by a 1/V variation. The characteristic velocity of this second cross-over depends on the roughness and the elastic stiffness. The statistical distribution of ballistic flight distances is analysed, and is shown to reveal in all cases the self-affinity of the contacting surfaces. Nous analysons la dépendence en vitesse du frottement entre deux solides limités par une surface rugueuse auto-affine comme celle d'une surface de fracture. Le solide supérieur est soumis soit à la gravité, soit à une raideur élastique externe, et est entraîné à vitesse horizontale constante V sur le solide inférieur fixe. A faible vitesse, le coefficient de friction apparent, est constant. A forte vitesse, le coefficient de friction apparent devient inversement proportionnel à la vitesse. Cette dépendance peut être reliée à la variation du temps

  5. Data Stream Clustering With Affinity Propagation

    KAUST Repository

    Zhang, Xiangliang

    2014-07-09

    Data stream clustering provides insights into the underlying patterns of data flows. This paper focuses on selecting the best representatives from clusters of streaming data. There are two main challenges: how to cluster with the best representatives and how to handle the evolving patterns that are important characteristics of streaming data with dynamic distributions. We employ the Affinity Propagation (AP) algorithm presented in 2007 by Frey and Dueck for the first challenge, as it offers good guarantees of clustering optimality for selecting exemplars. The second challenging problem is solved by change detection. The presented StrAP algorithm combines AP with a statistical change point detection test; the clustering model is rebuilt whenever the test detects a change in the underlying data distribution. Besides the validation on two benchmark data sets, the presented algorithm is validated on a real-world application, monitoring the data flow of jobs submitted to the EGEE grid.

  6. Bees visitors of three species of Clusia (Clusiaceae flowers in Central Amazonia Abelhas visitantes de flores de três espécies de Clusia (Clusiacea na Amazônia Central

    Directory of Open Access Journals (Sweden)

    Ana Claudia Kaminski

    2006-01-01

    Full Text Available Observations on bees visitors to three species of Clusia (Clusiaceae flowers in the Reserva Adolpho Ducke, Manaus, Amazonas, Brazil were made during three two-week periods. The three species of Clusia, namely C. grandiflora, C. panapanari and C. insignis, presented variations regarding the species of bee visitors. A total of 23 bee species visited the three species of Clusia. The Euglossini and Meliponinae bees were the most frequent visitors of the Clusia flowers. Bee collecting behavior of floral resources is described.Durante seis semanas foram realizadas observações das abelhas visitantes de flores de três espécies de Clusia (Clusiaceae, na Reserva Florestal Adolpho Ducke, em Manaus. As três espécies de Clusia: C. grandiflora Splitg., C. panapanari (Aubl. e C. insignis Mart. apresentaram diferenças com relação às visitas de espécies de abelhas, tendo sido visitadas por 23 espécies. Abelhas Euglossini e Meliponinae foram os visitantes mais freqüentes em flores de Clusia. O comportamento de coleta de recursos florais é descrito.

  7. Indefinite Affine Hyperspheres Admitting a Pointwise Symmetry. Part 2

    Directory of Open Access Journals (Sweden)

    Christine Scharlach

    2009-10-01

    Full Text Available An affine hypersurface M is said to admit a pointwise symmetry, if there exists a subgroup G of Aut(T_pM for all p in M, which preserves (pointwise the affine metric h, the difference tensor K and the affine shape operator S. Here, we consider 3-dimensional indefinite affine hyperspheres, i.e. S = HId (and thus S is trivially preserved. In Part 1 we found the possible symmetry groups G and gave for each G a canonical form of K. We started a classification by showing that hyperspheres admitting a pointwise Z_2 × Z_2 resp. R-symmetry are well-known, they have constant sectional curvature and Pick invariant J < 0 resp. J = 0. Here, we continue with affine hyperspheres admitting a pointwise Z_3- or SO(2-symmetry. They turn out to be warped products of affine spheres (Z_3 or quadrics (SO(2 with a curve.

  8. Gravitation, Electromagnetism and the Cosmological Constant in Purely Affine Gravity

    Science.gov (United States)

    Popławski, Nikodem J.

    The Eddington Lagrangian in the purely affine formulation of general relativity generates the Einstein equations with the cosmological constant. The Ferraris-Kijowski purely affine Lagrangian for the electromagnetic field, which has the form of the Maxwell Lagrangian with the metric tensor replaced by the symmetrized Ricci tensor, is dynamically equivalent to the Einstein-Maxwell Lagrangian in the metric formulation. We show that the sum of the two affine Lagrangians is dynamically inequivalent to the sum of the analogous Lagrangians in the metric-affine/metric formulation. We also show that such a construction is valid only for weak electromagnetic fields. Therefore the purely affine formulation that combines gravitation, electromagnetism and the cosmological constant cannot be a simple sum of terms corresponding to separate fields. Consequently, this formulation of electromagnetism seems to be unphysical, unlike the purely metric and metric-affine pictures, unless the electromagnetic field couples to the cosmological constant.

  9. Classical affine W-algebras associated to Lie superalgebras

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Uhi Rinn, E-mail: uhrisu1@math.snu.ac.kr [Department of Mathematical Sciences, Seoul National University, GwanAkRo 1, Gwanak-Gu, Seoul 151-747 (Korea, Republic of)

    2016-02-15

    In this paper, we prove classical affine W-algebras associated to Lie superalgebras (W-superalgebras), which can be constructed in two different ways: via affine classical Hamiltonian reductions and via taking quasi-classical limits of quantum affine W-superalgebras. Also, we show that a classical finite W-superalgebra can be obtained by a Zhu algebra of a classical affine W-superalgebra. Using the definition by Hamiltonian reductions, we find free generators of a classical W-superalgebra associated to a minimal nilpotent. Moreover, we compute generators of the classical W-algebra associated to spo(2|3) and its principal nilpotent. In the last part of this paper, we introduce a generalization of classical affine W-superalgebras called classical affine fractional W-superalgebras. We show these have Poisson vertex algebra structures and find generators of a fractional W-superalgebra associated to a minimal nilpotent.

  10. Entomofauna asociada a flores de berenjena y su papel en la producción de los frutos Insects associated with eggplant flowers and their role in fruit production

    Directory of Open Access Journals (Sweden)

    Julianne Milléo

    2011-06-01

    Full Text Available El papel de los insectos polinizadores despierta interés, principalmente, en la reproducción de plantas tales como la berenjena. Este trabajo de recolección de la entomofauna asociada a las flores de Solanum melongena tuvo como objetivos identificar posibles agentes polinizadores locales y analizar el beneficio de los insectos antófilos a esta planta. Las observaciones y la colecta de los insectos visitantes de las flores fueron realizadas en febrero de 2008, entre las 7:00 y 17:15 horas, cada 45 minutos y en un área de 27 m². El experimento para el análisis y la comparación entre autofecundación espontánea y polinización por medio de agentes bióticos fue realizado en el mismo sitio, de febrero a marzo de 2009. Fueron colectados 631 insectos que visitaban las flores de berenjena, se destacaron los coleópteros de los géneros Colaspis Fabricius, Astylus Laporte, Harmonia Mulsant, Epitrix Foudras y Diabrotica Chevrolat; y los himenópteros del género Bombus Latreille. El pico de visitación en Solanum melongena ocurrió entre las 9:00 y 11:00 horas y corresponde al 36% del muestreo. De las flores sometidas al test de autofecundación espontánea, el 39% formaron frutos, mientras que apenas el 11% de las flores emasculadas y expuestas al proceso de acción por medio de agentes bióticos fructificaron.The interest in the role of insect pollination is growing, mainly in the reproduction of plants of economic interest, such as the eggplant. This study about the entomofauna associated with flowers of Solanum melongena has as objectives to identify possible pollinators' agents and to analyze the benefit of the anthophile insects to this plant. The observations and the survey of the flower visitors' insects were made in February 2008, between 7:00 am and 5:15 pm, every 45 minutes, in an area of 27 m². The experiment for analysis and comparison between spontaneous self pollination and by biological agents was made at the same place, from

  11. Interactions between carpenter bees and orchid bees (Hymenoptera: Apidae in flowers of Bertholletia excelsa Bonpl. (Lecythidaceae Interações entre abelhas carpinteiras e abelhas das orquídeas (Hymenoptera: Apidae em flores de Bertholletia excelsa Bonpl. (Lecythidaceae

    Directory of Open Access Journals (Sweden)

    Charles Fernando dos Santos

    2012-03-01

    Full Text Available Competition between two species of bees for the same type of floral resource may generate antagonistic behavior between them, especially in cultivated areas where food resources are limited, seasonally and locally. In this study, was tested the hypothesis of antagonism between two solitary bee species of the family Apidae, Eulaema mocsaryi (Euglossini and Xylocopa frontalis (Xylocopini, visiting the Brazil nut flowers (Bertholletia excelsa: Lecythidaceae in a central Amazonia agricultural area. The visitation time was analyzed to detect the possible temporal overlap in the foraging of these bees. Furthermore, was analyzed their interspecific interactions for manipulating flower species visited by an opponent species, as well as attempts to attack this opponent. The individuals of Xylocopa frontalis visited the Brazil nut flowers before Eulaema mocsaryi, although the peak visitation of both did not presented significant differences. Neither of the species manipulated flowers recently visited by opponent species, and there were practically no antagonistic interactions between them. Thus, X. frontalis and E. mocsaryi shared the same food source in the flowers of B. excelsa due to differences in their time of visits and non-aggressive way of interacting with the opponent. This result has important implications for pollinating the Brazil nut, and a possible management of X. frontalis and E. mocsaryi, since these two were the most abundant pollinators in the studied locality.A competição entre duas espécies de abelhas por um mesmo tipo de recurso floral pode gerar comportamentos antagônicos entre elas, principalmente, dentro de áreas cultivadas, onde o recurso alimentar é limitado sazonalmente e localmente. No presente trabalho, foi testada a hipótese de antagonismo entre duas espécies de abelhas solitárias da família Apidae, Eulaema mocsaryi (Euglossini e Xylocopa frontalis (Xylocopini em flores da castanheira do Brasil (Bertholletia

  12. Surfaces in 4-space from the affine differential geometry viewpoint

    OpenAIRE

    Luis Florial Espinoza Sánchez

    2014-01-01

    In this thesis, we study locally strictly convex surfaces from the affine differential viewpoint and generalize some tools for locally strictly submanifolds of codimension 2. We introduce a family of affine metrics on a locally strictly convex surface M in affine 4-space. Then, we define the symmetric and antisymmetric equiaffine planes associated with each metric. We show that if M is immersed in a locally atrictly convex hyperquadric, then the symmetric and the antisymmetric planes coincid...

  13. Fast Affinity Propagation Clustering based on Machine Learning

    OpenAIRE

    Shailendra Kumar Shrivastava; J. L. Rana; DR.R.C.JAIN

    2013-01-01

    Affinity propagation (AP) was recently introduced as an un-supervised learning algorithm for exemplar based clustering. In this paper a novel Fast Affinity Propagation clustering Approach based on Machine Learning (FAPML) has been proposed. FAPML tries to put data points into clusters based on the history of the data points belonging to clusters in early stages. In FAPML we introduce affinity learning constant and dispersion constant which supervise the clustering process. FAPML also enforces...

  14. Abacus models for parabolic quotients of affine Weyl groups

    CERN Document Server

    Hanusa, Christopher R H

    2011-01-01

    We introduce abacus diagrams that describe minimal length coset representatives in affine Weyl groups of types B, C, and D. These abacus diagrams use a realization of the affine Weyl group of type C due to Eriksson to generalize a construction of James for the symmetric group. We also describe several combinatorial models for these parabolic quotients that generalize classical results in affine type A related to core partitions.

  15. Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing

    Science.gov (United States)

    Reshetova, Polina; van Schaik, Barbera D. C.; Klarenbeek, Paul L.; Doorenspleet, Marieke E.; Esveldt, Rebecca E. E.; Tak, Paul-Peter; Guikema, Jeroen E. J.; de Vries, Niek; van Kampen, Antoine H. C.

    2017-01-01

    Immunoglobulin repertoire sequencing has successfully been applied to identify expanded antigen-activated B-cell clones that play a role in the pathogenesis of immune disorders. One challenge is the selection of the Ag-specific B cells from the measured repertoire for downstream analyses. A general feature of an immune response is the expansion of specific clones resulting in a set of subclones with common ancestry varying in abundance and in the number of acquired somatic mutations. The expanded subclones are expected to have BCR affinities for the Ag higher than the affinities of the naive B cells in the background population. For these reasons, several groups successfully proceeded or suggested selecting highly abundant subclones from the repertoire to obtain the Ag-specific B cells. Given the nature of affinity maturation one would expect that abundant subclones are of high affinity but since repertoire sequencing only provides information about abundancies, this can only be verified with additional experiments, which are very labor intensive. Moreover, this would also require knowledge of the Ag, which is often not available for clinical samples. Consequently, in general we do not know if the selected highly abundant subclone(s) are also the high(est) affinity subclones. Such knowledge would likely improve the selection of relevant subclones for further characterization and Ag screening. Therefore, to gain insight in the relation between subclone abundancy and affinity, we developed a computational model that simulates affinity maturation in a single GC while tracking individual subclones in terms of abundancy and affinity. We show that the model correctly captures the overall GC dynamics, and that the amount of expansion is qualitatively comparable to expansion observed from B cells isolated from human lymph nodes. Analysis of the fraction of high- and low-affinity subclones among the unexpanded and expanded subclones reveals a limited correlation between

  16. Inhibition of Xanthine Oxidase Activity by Gnaphalium Affine Extract

    Institute of Scientific and Technical Information of China (English)

    Wei-qing Lin; Jian-xiang Xie; Xiao-mu Wu; Lin Yang; Hai-dong Wang

    2014-01-01

    Objective To evaluate the inhibitory effect of Gnaphalium affine extracts on xanthine oxidase (XO) activity in vitro and to analyze the mechanism of this effect. Methods In this in vitro study, Kinetic measurements were performed in 4 different inhibitor concentrations and 5 different xanthine concentrations (60, 100, 200, 300, 400 μmol/L). Dixon and Lineweaver-Burk plot analysis were used to determine Ki values and the inhibition mode for the compounds isolated from Gnaphalium affine extract. Results Four potent xanthine oxidase inhibitors were found in 95% ethanolic (v/v) Gnaphalium affine extract. Among them, the flavone Eupatilin exhibited the strongest inhibitory effect on XO with a inhibition constant (Ki) of 0.37μmol/L, lower than the Ki of allopurinol (4.56 mol/L), a known synthetic XO inhibitor. Apigenin (Ki of 0.56μmol/L, a proportion of 0.0053‰in Gnaphalium affine), luteolin (Ki of 2.63 μmol/L, 0.0032‰ in Gnaphalium affine) and 5-hydroxy-6,7,3’,4’-tetramethoxyflavone (Ki of 3.15μmol/L, 0.0043‰ in Gnaphalium affine) also contributed to the inhibitory effect of Gnaphalium affine extract on XO activity. Conclusions These results suggest that the use of Gnaphalium affine in the treatment of gout could be attributed to its inhibitory effect on XO. This study provides a rational basis for the traditional use of Gnaphalium affine against gout.

  17. Ganglioside embedded in reconstituted lipoprotein binds cholera toxin with elevated affinity.

    Science.gov (United States)

    Bricarello, Daniel A; Mills, Emily J; Petrlova, Jitka; Voss, John C; Parikh, Atul N

    2010-09-01

    The ability to exogenously present cell-surface receptors in high-affinity conformations in a synthetic system offers an opportunity to provide host cells with protection from pathogenic toxins. This strategy requires improvement of the synthetic receptor binding affinity against its native counterpart, particularly with polyvalent toxins where clustering of membrane receptors can hinder binding. Here we demonstrate that reconstituted lipoprotein, nanometer-sized discoidal lipid bilayers bounded by apolipoprotein and functionalized by incorporation of pathogen receptors, provides a means to enhance toxin-receptor binding through molecular-level control over the receptor microenvironment (specifically, its rigidity, composition, and heterogeneity). Using a Foerster Resonance Energy Transfer (FRET)-based assay, we found that reconstituted lipoprotein incorporating low concentrations of ganglioside monosialotetrahexosylganglioside (GM1) binds polymeric cholera toxin with significantly higher affinity than liposomes or supported lipid bilayers, most likely a result of the enhanced control over receptor clustering provided by the lipoprotein platform. Using wide-area epifluorescence, we found that this enhanced binding capacity can be effectively utilized to divert cholera toxin away from populations of healthy mammalian cells. In summary, we found that reconstitutions of high-density lipoprotein can be engineered to include specific pathogen receptors; that their pathogen binding affinity is altered, presumably due to attenuation of receptor aggregation; and that these assemblies are effective at protecting cells from biological toxins.

  18. A robust assay to measure DNA topology-dependent protein binding affinity.

    Science.gov (United States)

    Litwin, Tamara R; Solà, Maria; Holt, Ian J; Neuman, Keir C

    2015-04-20

    DNA structure and topology pervasively influence aspects of DNA metabolism including replication, transcription and segregation. However, the effects of DNA topology on DNA-protein interactions have not been systematically explored due to limitations of standard affinity assays. We developed a method to measure protein binding affinity dependence on the topology (topological linking number) of supercoiled DNA. A defined range of DNA topoisomers at equilibrium with a DNA binding protein is separated into free and protein-bound DNA populations using standard nitrocellulose filter binding techniques. Electrophoretic separation and quantification of bound and free topoisomers combined with a simple normalization procedure provide the relative affinity of the protein for the DNA as a function of linking number. Employing this assay we measured topology-dependent DNA binding of a helicase, a type IB topoisomerase, a type IIA topoisomerase, a non-specific mitochondrial DNA binding protein and a type II restriction endonuclease. Most of the proteins preferentially bind negatively supercoiled DNA but the details of the topology-dependent affinity differ among proteins in ways that expose differences in their interactions with DNA. The topology-dependent binding assay provides a robust and easily implemented method to probe topological influences on DNA-protein interactions for a wide range of DNA binding proteins.

  19. The cohomology of the affine Deligne-Lusztig varieties in the affine flag manifold of $GL_2$

    CERN Document Server

    Ivanov, Alexander

    2009-01-01

    This paper studies affine Deligne-Lusztig varieties in the affine flag manifold of GL_2. At first we determine all such varieties up to isomorphy. After this we investigate the representations of the sigma-stabilizer of an element b of the group on the etale cohomology of the affine Deligne-Lusztig variety X_w(b). We describe such representations as inductions from compact subgroups and in terms of noncuspidal representations.

  20. Aspectos de la relación entre Thalurania Furcata Colombica (Aves Trochilidae y las flores en que liba, en un bosque subandino Aspectos de la relación entre Thalurania Furcata Colombica (Aves Trochilidae y las flores en que liba, en un bosque subandino

    Directory of Open Access Journals (Sweden)

    Ayala R. Ana Victoria

    1986-06-01

    Full Text Available El mayor nivel de coadaptación ave nectarívora-flor conocido hasta el momento, se ha logrado en los Trochilidae (VAN DER PIJL & DODSON,1969; FEINSINGER et al., 1979 ; tanto, que se ha hablado de flores adaptadas a la polinización por una especie particular de colibrí, y de colibríes que dependen para su alimentación de una sola clase de flor (SNOW & SNOW, 1980.Los factores principales que afectan la selección de alimento por parte de los colibríes están relacionados con: hábitat y estratificación de la vegetación (STILES & VVOLF,1970; FEINSINGER & CoLWELL, 1978, distribución espacial y características de las flores (FEINSINGER & COLYVELL,1978; FEINSINGER et al., 1979, distribución temporal del alimento (WOLF et al., 1976, morfología del pico del ave (FEINSINGER & COLWELL, 1978; STILES, 1978 a; FEINSINGER et al., 1979, tamaño del cuerpo (VVOLF et al., 1976, "disco de sustentación del ala" (wing disc loading y, finalmente, la energía que el colibrí requiere para sustentarse en el aire (EPTING & CASEY, 1973; WOLF et al., 1976. Colombia está incluida en el área central de evolución de los Trochilidae (SNOW & SNOW,- 1980 y posee numerosas especies así como riqueza de hábitats ocupados por ellos. Al igual que trabajos anteriores (SNOW & SNOW, 1980; MURCIA, 1983, el presente aporta al conocimiento de la ecología de los colibríes en este país; especificamente, trata algunos aspectos de la interacción Thalurania furcata colombica-flor proveedora de alimento en un Bosque Subandino. Between April and September 1983 observations were made on the relations between Thalurcnia furcata colombica and flowers in the laguna de Pedro Palo area (Cundinamarca, Colombia. The hummingbird was seen visiting 15 species of plants (beloging to 13 families situated mainly on the edge of forest, among which the following species showed a high degree of ornithophily: Besleria solanoides (Gesneriaceae, Bomarea racemose (Amaryllidaceae

  1. Composição físico-química do vinho Bordô de Flores da Cunha, RS, elaborado com uvas maturadas em condições de baixa precipitação Physicochemical composition of Bordô wines from Flores da Cunha, RS, made with grapes matured in low rain conditions

    Directory of Open Access Journals (Sweden)

    Francine Maria Tecchio

    2007-10-01

    Full Text Available O Bordô é, depois do Isabel, o vinho de mesa de maior importância econômica na Serra Gaúcha, pois existe um considerável segmento de mercado que o aprecia, especialmente por seu sabor frutado e por sua cor intensa e matiz violeta. Devido a isso e às condições de estiagem que ocorreram no verão de 2005, quando as chuvas corresponderam a 38% da normal climatológica, analisaram-se vinhos Bordô do município de Flores da Cunha, RS, um dos mais importantes produtores da Serra Gaúcha. Os vinhos analisados eram varietalmente puros e elaborados segundo a tecnologia de cada vinícola. Avaliaram-se 39 variáveis, das quais os resultados mais expressivos foram os seguintes: álcool 10,58% v/v; acidez total 91meq L-1; acidez volátil 7,3meq L-1; pH 3,21; extrato seco 24,24g L-1; açúcares redutores 2,90g L-1; extrato seco reduzido 22,34g L-1; cinzas 2,09g L-1; ácido tartárico 5,35g L-1; DO 420 0,480; DO 520 1,296; DO 620 0,184; taninos 1,41g L-1; antocianinas 778,8mg L-1; etanal 14,9mg L-1; acetato de etila 59,3mg L-1; metanol 290,9mg L-1; 1-propanol 24,9mg L-1; 2-metiL-1-propanol 40,6mg L-1; 2-metiL-1-butanol 45,9mg L-1; 3-metiL-1-butanol 149,1mg L-1; soma dos álcoois superiores 260,5mg L-1; e K 953mg L-1.The Bordô, after Isabel, is the table wine presenting the greater economic importance in the Serra Gaúcha region, because there is a segment of the market that likes its characteristics, specially its fruity flavor, color intensity, and violet hue. Due to these aspects and to the very dry climatic conditions in the 2005 summer, where rain represented 38% of the climatological normal, Bordô wines were analyzed from the commune of Flores da Cunha, RS, Brazil, one of the most important producers of the Serra Gaúcha region. Analyzed wines were varietal ones and made according to the technology of each winery. Thirty nine variables were evaluated and the average parameters of the most expressive ones were the following: alcohol 10.58% v

  2. Affine connection form of Regge calculus

    Science.gov (United States)

    Khatsymovsky, V. M.

    2016-12-01

    Regge action is represented analogously to how the Palatini action for general relativity (GR) as some functional of the metric and a general connection as independent variables represents the Einstein-Hilbert action. The piecewise flat (or simplicial) spacetime of Regge calculus is equipped with some world coordinates and some piecewise affine metric which is completely defined by the set of edge lengths and the world coordinates of the vertices. The conjugate variables are the general nondegenerate matrices on the three-simplices which play the role of a general discrete connection. Our previous result on some representation of the Regge calculus action in terms of the local Euclidean (Minkowsky) frame vectors and orthogonal connection matrices as independent variables is somewhat modified for the considered case of the general linear group GL(4, R) of the connection matrices. As a result, we have some action invariant w.r.t. arbitrary change of coordinates of the vertices (and related GL(4, R) transformations in the four-simplices). Excluding GL(4, R) connection from this action via the equations of motion we have exactly the Regge action for the considered spacetime.

  3. Platelet affinity for burro aorta collagen

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, M.D.

    1977-10-01

    Despite ingenious concepts, there are no unequivocal clues as to what, when, and how some undefined biochemical factor(s) or constituent(s) that localizes in the arterial wall can precipitate a thromboatheromatous lesion or arterial disease. The present study focused on the extraction, partial purification, and characterization of a collagen-active platelet stimulator from the aortas of aged burros. The aggregator moiety in the aorta extracts invariably had a higher affinity for platelets in citrated platelet-rich plasma of human beings than for platelets of homologous burros. The platelet-aggregating factor(s) in the aorta extract was retained by incubation with ..cap alpha..-chymotrypsin. Platelet-aggregating activity was rapidly abolished after incubation with collagenase, as determined by platelet-aggregometry tests. Evidence based on light microscope and polysaccharide histochemical reactions indicates a probability that the intracellular amorphous matrix (PAS-positive) and filamentous components (PTAH-positive) expelled from smooth muscle cells disrupted during homogenization of the aorta may be a principal source of a precursor collagen species which is a potent inducer of platelet aggregation.

  4. Affinity of guanosine derivatives for polycytidylate revisited

    Science.gov (United States)

    Kanavarioti, A.; Hurley, T. B.; Baird, E. E.

    1995-01-01

    Evidence is presented for complexation of guanosine 5'-monophosphate 2-methylimidazolide (2-MeImpG) with polycytidylate (poly(C)) at pH 8.0 and 23 degrees C in the presence of 1.0 M NaCl2 and 0.2 M MgCl2 in water. The association of 2-MeImpG with poly(C) was investigated using UV-vis spectroscopy as well as by monitoring the kinetics of the nucleophilic substitution reaction of the imidazole moiety by amines. The results of both methods are consistent with moderately strong poly(C) 2-MeImpG complexation and the spectrophotometric measurements allowed the construction of a binding isotherm with a concentration of 2-MeImpG equal to 5.55 +/- 0.15 mM at half occupancy. UV spectroscopy was employed to establish the binding of other guanosine derivatives on poly(C). These derivatives are guanosine 5'-monophosphate (5'GMP), guanosine 5'-monophosphate imidazolide (ImpG), and guanosine 5'-monophosphate morpholidate (morpG). Within experimental error these guanosine derivatives exhibit the same affinity for poly(C) as 2-MeImpG.

  5. SHP-1 phosphatase activity counteracts increased T cell receptor affinity.

    Science.gov (United States)

    Hebeisen, Michael; Baitsch, Lukas; Presotto, Danilo; Baumgaertner, Petra; Romero, Pedro; Michielin, Olivier; Speiser, Daniel E; Rufer, Nathalie

    2013-03-01

    Anti-self/tumor T cell function can be improved by increasing TCR-peptide MHC (pMHC) affinity within physiological limits, but paradoxically further increases (K(d) affinity for the tumor antigen HLA-A2/NY-ESO-1, we investigated the molecular mechanisms underlying this high-affinity-associated loss of function. As compared with cells expressing TCR affinities generating optimal function (K(d) = 5 to 1 μM), those with supraphysiological affinity (K(d) = 1 μM to 15 nM) showed impaired gene expression, signaling, and surface expression of activatory/costimulatory receptors. Preferential expression of the inhibitory receptor programmed cell death-1 (PD-1) was limited to T cells with the highest TCR affinity, correlating with full functional recovery upon PD-1 ligand 1 (PD-L1) blockade. In contrast, upregulation of the Src homology 2 domain-containing phosphatase 1 (SHP-1/PTPN6) was broad, with gradually enhanced expression in CD8(+) T cells with increasing TCR affinities. Consequently, pharmacological inhibition of SHP-1 with sodium stibogluconate augmented the function of all engineered T cells, and this correlated with the TCR affinity-dependent levels of SHP-1. These data highlight an unexpected and global role of SHP-1 in regulating CD8(+) T cell activation and responsiveness and support the development of therapies inhibiting protein tyrosine phosphatases to enhance T cell-mediated immunity.

  6. High affinity retinoic acid receptor antagonists: analogs of AGN 193109.

    Science.gov (United States)

    Johnson, A T; Wang, L; Gillett, S J; Chandraratna, R A

    1999-02-22

    A series of high affinity retinoic acid receptor (RAR) antagonists were prepared based upon the known antagonist AGN 193109 (2). Introduction of various phenyl groups revealed a preference for substitution at the para-position relative to the meta-site. Antagonists with the highest affinities for the RARs possessed hydrophobic groups, however, the presence of polar functionality was also well tolerated.

  7. Striving for Empathy: Affinities, Alliances and Peer Sexuality Educators

    Science.gov (United States)

    Fields, Jessica; Copp, Martha

    2015-01-01

    Peer sexuality educators' accounts of their work reveal two approaches to empathy with their students: affinity and alliance. "Affinity-based empathy" rests on the idea that the more commonalities sexuality educators and students share (or perceive they share), the more they will be able to empathise with one another, while…

  8. Ordinary matter in nonlinear affine gauge theories of gravitation

    CERN Document Server

    Tiemblo, A; Tiemblo, A; Tresguerres, R

    1994-01-01

    We present a general framework to include ordinary fermionic matter in the metric--affine gauge theories of gravity. It is based on a nonlinear gauge realization of the affine group, with the Lorentz group as the classification subgroup of the matter and gravitational fields.

  9. Isolation of bovine serum albumin from whey using affinity chromatography

    NARCIS (Netherlands)

    Besselink, T.; Janssen, A.E.M.; Boom, R.M.

    2015-01-01

    The adsorption of bovine serum albumin (BSA) to a chromatography resin with immobilised llama antibody fragments as affinity ligands was investigated. The maximum adsorption capacity of the affinity resin was 21.6 mg mL-1 with a Langmuir equilibrium constant of 20.4 mg mg-1. Using packed bed chromat

  10. Striving for Empathy: Affinities, Alliances and Peer Sexuality Educators

    Science.gov (United States)

    Fields, Jessica; Copp, Martha

    2015-01-01

    Peer sexuality educators' accounts of their work reveal two approaches to empathy with their students: affinity and alliance. "Affinity-based empathy" rests on the idea that the more commonalities sexuality educators and students share (or perceive they share), the more they will be able to empathise with one another, while…

  11. Convergence of generic infinite products of affine operators

    Directory of Open Access Journals (Sweden)

    S. Reich

    1999-01-01

    Full Text Available We establish several results concerning the asymptotic behavior of random infinite products of generic sequences of affine uniformly continuous operators on bounded closed convex subsets of a Banach space. In addition to weak ergodic theorems we also obtain convergence to a unique common fixed point and more generally, to an affine retraction.

  12. Gray-Scale Image Colorization Using Various Affinity Functions

    Directory of Open Access Journals (Sweden)

    Imron Rosyadi

    2012-02-01

    Full Text Available In this paper, we have proposed, implemented, and compared some affinity functions for an image colorization algorithm. The colorization qualityof the proposed affinityfunctions was just slightly behind the original functions, while one of the proposed functions performed faster than the original affinity function. We also implemented the colorization algorithm for coloring an Indonesian historical image.

  13. Affine group formulation of the Standard Model coupled to gravity

    Energy Technology Data Exchange (ETDEWEB)

    Chou, Ching-Yi, E-mail: l2897107@mail.ncku.edu.tw [Department of Physics, National Cheng Kung University, Taiwan (China); Ita, Eyo, E-mail: ita@usna.edu [Department of Physics, US Naval Academy, Annapolis, MD (United States); Soo, Chopin, E-mail: cpsoo@mail.ncku.edu.tw [Department of Physics, National Cheng Kung University, Taiwan (China)

    2014-04-15

    In this work we apply the affine group formalism for four dimensional gravity of Lorentzian signature, which is based on Klauder’s affine algebraic program, to the formulation of the Hamiltonian constraint of the interaction of matter and all forces, including gravity with non-vanishing cosmological constant Λ, as an affine Lie algebra. We use the hermitian action of fermions coupled to gravitation and Yang–Mills theory to find the density weight one fermionic super-Hamiltonian constraint. This term, combined with the Yang–Mills and Higgs energy densities, are composed with York’s integrated time functional. The result, when combined with the imaginary part of the Chern–Simons functional Q, forms the affine commutation relation with the volume element V(x). Affine algebraic quantization of gravitation and matter on equal footing implies a fundamental uncertainty relation which is predicated upon a non-vanishing cosmological constant. -- Highlights: •Wheeler–DeWitt equation (WDW) quantized as affine algebra, realizing Klauder’s program. •WDW formulated for interaction of matter and all forces, including gravity, as affine algebra. •WDW features Hermitian generators in spite of fermionic content: Standard Model addressed. •Constructed a family of physical states for the full, coupled theory via affine coherent states. •Fundamental uncertainty relation, predicated on non-vanishing cosmological constant.

  14. Self-affine roughness influence on redox reaction charge admittance

    NARCIS (Netherlands)

    Palasantzas, G

    2005-01-01

    In this work we investigate the influence of self-affine electrode roughness on the admittance of redox reactions during facile charge transfer kinetics. The self-affine roughness is characterized by the rms roughness amplitude w, the correlation length xi and the roughness exponent H (0

  15. Frame-independent mechanics:geometry on affine bundles

    OpenAIRE

    Grabowska, K.; Grabowski, J.; Urbanski, P.

    2005-01-01

    Main ideas of the differential geometry on affine bundles are presented. Affine counterparts of Lie algebroid and Poisson structures are introduced and discussed. The developed concepts are applied in a frame-independent formulation of the time-dependent and the Newtonian mechanics.

  16. Synthesis of tetracycline analogs and their bone affinities

    Institute of Scientific and Technical Information of China (English)

    Wen Cai Huang; Hu Zheng; Ling Ling Weng

    2008-01-01

    Tetracycline analogs were designed and synthesized and their bone affinities were tested on hydroxyapatite. The results showedthat the carbonyl-amide-enol structure in A ring and phenol-ketone structure in BCD ring may be responsible for tetracycline's highbone affinity and either A ring or BCD ring has a planar conformation is essential.

  17. The Affine Complete Hypersurfaces of Constant Gauss-Kronecker Curvature

    Institute of Scientific and Technical Information of China (English)

    Bao Fu WANG

    2009-01-01

    Given a bounded convex domain Ω with C∞ boundary and a function φ∈ C∞ ( partial deriv Ω), Li-Simon-Chen can construct an Euclidean complete and W-complete convex hypersurface M with constant affine Gauss-Kronecker curvature, and they guess the M is also affine complete. In this paper, we give a confirmation answer.

  18. Germinal center reaction: antigen affinity and presentation explain it all.

    Science.gov (United States)

    Oropallo, Michael A; Cerutti, Andrea

    2014-07-01

    The selection and expansion of B cells undergoing affinity maturation in the germinal center is a hallmark of humoral immunity. A recent paper in Nature provides new insights into the relationships between the affinity of the immunoglobulin receptor for antigen, the ability of B cells to present antigen to T cells, and the processes of selection, mutation, and clonal expansion in the germinal center.

  19. Peptide Nucleic Acids Having Enhanced Binding Affinity and Sequence Specificity

    DEFF Research Database (Denmark)

    1998-01-01

    A novel class of compounds, known as peptide nucleic acids, bind complementary DNA and RNA strands more strongly than a corresponding DNA strand, and exhibit increased sequence specificity and binding affinity. Methods of increasing binding affinity and sequence specificity of peptide nucleic aci...

  20. Downstream processing of polysaccharide degrading enzymes by affinity chromatography.

    NARCIS (Netherlands)

    Somers, W.A.C.

    1992-01-01

    The objective of this study was the development of affinity matrices to isolate and purify a number of polysaccharide degrading enzymes and the application of these adsorbents in the large- scale purification of the enzymes from fermentation broths. Affinity adsorbents were developed for endo-polyga

  1. THE REPRESENTATION OF THE DIVINE AND HUMAN BEING IMAGERY IN THE ENTITY OF RITUS SA’O NGAZA IN GURU SINA, NGADA, FLORES

    Directory of Open Access Journals (Sweden)

    Watu Yohanes Vianey

    2012-11-01

    Full Text Available This dissertation discusses the representation of the Divine and human being imagery in theentity of ritus Sa’o Ngaza in the village of Guru Sina in Ngada Regency, Flores. The empiricproblems of this dissertasion are connected with the marginalized phenomenon of the local religionthat submerged in the entity of ritus Sa’o Ngaza and its ritual practices. This probelm is relevant tobe investigated from the perspectives cultural studies.The problems raised in this study are : 1 the representation of the Divine and human beingimagery in the entity of ritus Sa’o Ngaza, 2 the representation of the relationhip between the Divineand human being in ritual practices of Sa’o Ngaza, and 3 the meaning of the representation of theDivine and human being imagery in the entity of ritus Sa’o Ngaza. This study applies the qualitativemethod and the data collection was done using techniques of intensive interview, participationobservation,and documentation. The data were analyzed using the theory of ritus, the theory ofprocess,the theory of semiotics, and the theory of deconstruction.The findings of the study can be explained as follows. Firstly, the representation of theDivine imagery is dyadic and triadic. In the dyadic imagery representation, The Divine is depicted as’The Giver of an Unlimited Love and at the same time as ’The Unpredictable Taker of Love’. In thetriadic representation, The Divine is depicted as The Sacred, in the attributive as ‘The Beginning’,‘The End’, and ‘The Present Throughout’. In the dyadic imagery, the human being consists of theelements of the body and the soul, and in the triadic imagery, the human being consists of theelements of the body, the psyche, and the spirit.Secondly, the relation between the Divine and human being is representatively revealed inthe ritual practices of legitimating Sa’o Ngaza. This relation centers in the methapor of relationshipbetween the simbolic body dan the religious body, and

  2. Insectos asociados con flores de malezas del Jardín Botánico de Santiago de Cuba, con énfasis en Hymenoptera

    Directory of Open Access Journals (Sweden)

    José L. Fernández T.

    2001-12-01

    Full Text Available Se estudiaron los insectos visitantes en flores de nueve especies de malezas del Jardín Botánico de Santiago de Cuba, Cuba Oriental, durante 1993 (marzo a junio, en primavera y 1994 (enero a marzo, final del invierno y comienzo de la primavera. Se contabilizaron unas 50 horas de recolecta en tres horarios diferentes (0900-0930 hr en 1993; 0900-0930 hr, 1200-1230 hr y 1500-1530 hr en 1994. Se identificaron más de 140 especies y por lo menos 37 familias; Hymenoptera fue el orden mejor representado (con más de la mitad de los individuos rerecolectados, seguido de Diptera, Coleoptera y Lepidoptera. Dentro de Hymenoptera las abejas (Apoidea fueron mayoritarias, especialmente Apis mellifera L.; seguidas de avispas (Vespidae, Pompilidae, Sphecidae e icneumónidos (Ichneumonidae; los microhimenópteros no se recolectaron. Se comparó la himenopterofauna en cuanto a diversidad, similitud, especies dominantes y subdominantes, preferencia de horarios, eficiencia de los muestreos, etc. Cada especie de planta sustentó una fauna característica. Casi un tercio de los himenópteros visitantes fueron controles biológicos de plagas agrícolas, y la mayoría pueden considerarse polinizadores. Especies afines filogenéticamente presentaron patrones de actividad diaria semejante. El horario 0900 -0930 hr fue el de mayor biodiversidad en cuanto a número de especies visitantes. Al analizar el número de especies con relación al número de especímenes rerecolectados, así como el total de especies y número de muestreos realizados, las funciones de mejor ajuste fueron polinomiales de segundo grado (r² = 0.9734 y r² = 0.9573 respectivamente, p The insect visitors of flowers in nine weeds species were studied in the Botanical Garden of Santiago de Cuba, Eastern Cuba, during 1993 (March - June, spring season and 1994 (January - March, end of winter and beginning of spring season. About 50 hours of collecting efforts were made at three times (0900-0930 hr in

  3. Volatility Components, Affine Restrictions and Non-Normal Innovations

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Jacobs, Kris; Dorian, Christian

    Recent work by Engle and Lee (1999) shows that allowing for long-run and short-run components greatly enhances a GARCH model's ability fit daily equity return dynamics. Using the risk-neutralization in Duan (1995), we assess the option valuation performance of the Engle-Lee model and compare...... it to the standard one-component GARCH(1,1) model. We also compare these non-affine GARCH models to one- and two- component models from the class of affine GARCH models developed in Heston and Nandi (2000). Using the option pricing methodology in Duan (1999), we then compare the four conditionally normal GARCH...... models to four conditionally non-normal versions. As in Hsieh and Ritchken (2005), we find that non-affine models dominate affine models both in terms of fitting return and in terms of option valuation. For the affine models we find strong evidence in favor of the component structure for both returns...

  4. Affinity Monolith-Integrated Microchips for Protein Purification and Concentration.

    Science.gov (United States)

    Gao, Changlu; Sun, Xiuhua; Wang, Huaixin; Qiao, Wei; Hu, Bo

    2016-01-01

    Affinity chromatography is a valuable method to purify and concentrate minute amount of proteins. Monoliths with epoxy groups for affinity immobilization were prepared by direct in-situ photopolymerization of glycidyl methacrylate and ethylene glycol dimethacrylate in porogenic solvents consisting of 1-dodecanol and cyclohexanol. By integrating affinity monoliths onto a microfluidic system, targeted biomolecules can be captured and retained on affinity column, while other biomolecules having no specific interactions toward the immobilized ligands flow through the microchannel. Therefore, proteins which remain on the affinity column are purified and concentrated, and then eluted by appropriate solutions and finally, separated by microchip capillary electrophoresis. This integrated microfluidic device has been applied to the purification and separation of specific proteins (FITC-labeled human serum albumin and IgG) in a mixture.

  5. IMPLEMENTASI ENKRIPSI DEKRIPSI ALGORITMA AFFINE CIPHER BERBASIS ANDROID

    Directory of Open Access Journals (Sweden)

    Sasono Wibowo

    2014-11-01

    Full Text Available Perkembangan Teknologi Informasi yang cukup pesat khususnya dalam bidang komunikasi menjadikan komunikasi sangat mudah namun dalam implementasinya perlu adanya keamanan tentang informasi yang disampaikan. Dalam komunikasi antar orang pasti memiliki pembicaraan informasi yang bersifat privat atau orang lain tidak boleh tahu tentang pembicaraan yang terjadi. Diperlukannya keamanan untuk menjaga kerahasiaan informasi pada saat komunikasi. Masyarakat lebih sering menggunakan komunikasi dengan telepon seluler karena dinilai mudah dibawa dan tidak repot menggunakannya. Kriptografi yang biasa dikenal sebagai ilmu yang mempelajari bagaimana cara menyembunyikan pesan bisa diterapkan dalam aplikasi pada telepon seluler sebagai contoh smartphone android. Dengan mengimplementasikan algoritma affine cipher maka aplikasi yang akan dibuat bisa mengubah isi pesan yang ada dan dapat mengamankan informasi yang ada. Algoritma affine cipher merupakan perkembangan dari algoritma caesar dimana algoritma affine cipher menggunakan dua kunci. Dengan mengimplementasikan algoritma affine cipher ke dalam android maka diharapkan kita bisa menyimpan informasi dari siapapun tanpa terbaca. Kata Kunci : Kriptografi, Affine Cipher, android, Implementasi, Informasi

  6. When hummingbirds are the thieves: visitation effect on the reproduction of Neotropical snowbell Styrax ferrugineus Nees & Mart (Styracaceae Quando os beija-flores são os ladrões: efeito da visitação na reprodução de uma planta Neotropical Styrax ferrugineus Nees & Mart (Styracaceae

    Directory of Open Access Journals (Sweden)

    Pietro Kiyoshi Maruyama

    2012-03-01

    Full Text Available The spectrum of floral visitors associated with a particular plant is frequently larger than predicted by the traditional concept of floral syndromes and the role that unpredicted visitors play in plant reproduction deserves attention. Hummingbirds are frequently recorded visiting flowers with distinct floral syndromes, especially in some hummingbird flower poor ecosystem such as the Cerrado. In this study we investigated the effect of frequent hummingbird visits on the reproduction of melittophilous Styrax ferrugineus. The flowers were visited by many different insect groups and visits by hummingbirds were frequent, especially early in the morning when nectar availability was higher. Nectar parameters varied considerably during the flower life span, and was probably affected by the temperature variation during the day. Hummingbird exclusion experiments showed no effect in the fruit-set of the plant. The inability of hummingbirds to deplete all of the nectar produced in this mass-flowering plant, and the existence of another resource (pollen for the primary pollinator (large bees, are possible reasons why there was no perceptible hindrance of plant reproduction by the hummingbirds. Although no effect in the fruit-set was observed, the use of non-ornithophilous flowers must be important for hummingbirds, which are specialized nectar consumers.O espectro de visitantes florais associados a uma planta é frequentemente maior que o esperado pelo conceito tradicional de síndromes florais e o papel desses visitantes inesperados tem recebido mais atenção. Os beija-flores freqüentemente visitam flores com síndromes florais distintas, especialmente em alguns ecossistemas pobre em flores ornitófilas como o Cerrado. Investigamos aqui o efeito das visitas de beija-flores na reprodução de Styrax ferrugineus, uma espécie melitófila. As flores foram visitadas por diferentes grupos de insetos e as visitas por beija-flores foram frequentes

  7. Gravitation, Electromagnetism and Cosmological Constant in Purely Affine Gravity

    Science.gov (United States)

    Popławski, Nikodem J.

    2009-03-01

    The Ferraris-Kijowski purely affine Lagrangian for the electromagnetic field, that has the form of the Maxwell Lagrangian with the metric tensor replaced by the symmetrized Ricci tensor, is dynamically equivalent to the metric Einstein-Maxwell Lagrangian, except the zero-field limit, for which the metric tensor is not well-defined. This feature indicates that, for the Ferraris-Kijowski model to be physical, there must exist a background field that depends on the Ricci tensor. The simplest possibility, supported by recent astronomical observations, is the cosmological constant, generated in the purely affine formulation of gravity by the Eddington Lagrangian. In this paper we combine the electromagnetic field and the cosmological constant in the purely affine formulation. We show that the sum of the two affine (Eddington and Ferraris-Kijowski) Lagrangians is dynamically inequivalent to the sum of the analogous ( ΛCDM and Einstein-Maxwell) Lagrangians in the metric-affine/metric formulation. We also show that such a construction is valid, like the affine Einstein-Born-Infeld formulation, only for weak electromagnetic fields, on the order of the magnetic field in outer space of the Solar System. Therefore the purely affine formulation that combines gravity, electromagnetism and cosmological constant cannot be a simple sum of affine terms corresponding separately to these fields. A quite complicated form of the affine equivalent of the metric Einstein-Maxwell- Λ Lagrangian suggests that Nature can be described by a simpler affine Lagrangian, leading to modifications of the Einstein-Maxwell- ΛCDM theory for electromagnetic fields that contribute to the spacetime curvature on the same order as the cosmological constant.

  8. Chasing polys: Interdisciplinary affinity and its connection to physics identity

    Science.gov (United States)

    Scott, Tyler D.

    This research is based on two motivations that merge by means of the frameworks of interdisciplinary affinity and physics identity. First, a goal of education is to develop interdisciplinary abilities in students' thinking and work. But an often ignored factor is students interests and beliefs about being interdisciplinary. Thus, this work develops and uses a framework called interdisciplinary affinity. It encompasses students interests in making connections across disciplines and their beliefs about their abilities to make those connections. The second motivation of this research is to better understand how to engage more students with physics. Physics identity describes how a student sees themselves in relation to physics. By understanding how physics identity is developed, researchers and educators can identify factors that increase interest and engagement in physics classrooms. Therefore, physics identity was used in conjunction with interdisciplinary affinity. Using a mixed methods approach, this research used quantitative data to identify the relationships interdisciplinary affinity has with physics identity and the physics classroom. These connections were explored in more detail using a case study of three students in a high school physics class. Results showed significant and positive relationships between interdisciplinary affinity and physics identity, including the individual interest and recognition components of identity. It also identified characteristics of physics classrooms that had a significant, positive relationship with interdisciplinary affinity. The qualitative case study highlighted the importance of student interest to the relationship between interdisciplinary affinity and physics identity. It also identified interest and mastery orientation as key to understanding the link between interdisciplinary affinity and the physics classroom. These results are a positive sign that by understanding interdisciplinary affinity and physics identity

  9. Optimal affine-invariant matching: performance characterization

    Science.gov (United States)

    Costa, Mauro S.; Haralick, Robert M.; Shapiro, Linda G.

    1992-04-01

    The geometric hashing scheme proposed by Lamdan and Wolfson can be very efficient in a model-based matching system, not only in terms of the computational complexity involved, but also in terms of the simplicity of the method. In a recent paper, we discussed errors that can occur with this method due to quantization, stability, symmetry, and noise problems. These errors make the original geometric hashing technique unsuitable for use on the factory floor. Beginning with an explicit noise model, which the original Lamdan and Wolfson technique lacks, we derived an optimal approach that overcomes these problems. We showed that the results obtained with the new algorithm are clearly better than the results from the original method. This paper addresses the performance characterization of the geometric hashing technique, more specifically the affine-invariant point matching, applied to the problem of recognizing and determining the pose of sheet metal parts. The experiments indicate that with a model having 10 to 14 points, with 2 points of the model undetected and 10 extraneous points detected, and with the model points perturbed by Gaussian noise of standard deviation 3 (0.58 of range), the average amount of computation required to obtain an answer is equivalent to trying 11 of the possible three-point bases. The misdetection rate, measured by the percentage of correct bases matches that fail to verify, is 0.9. The percentage of incorrect bases that successfully produced a match that did verify (false alarm rate) is 13. And, finally, 2 of the experiments failed to find a correct match and verify it. Results for experiments with real images are also presented.

  10. Affinity capillary electrophoresis: the theory of electromigration.

    Science.gov (United States)

    Dubský, Pavel; Dvořák, Martin; Ansorge, Martin

    2016-12-01

    We focus on the state-of-the-art theory of electromigration under single and multiple complexation equilibrium. Only 1:1 complexation stoichiometry is discussed because of its unique status in the field of affinity capillary electrophoresis (ACE). First, we summarize the formulas for the effective mobility in various ACE systems as they appeared since the pioneering days in 1992 up to the most recent theories till 2015. Disturbing phenomena that do not alter the mobility of the analyte directly but cause an unexpected peak broadening have been studied only recently and are also discussed in this paper. Second, we turn our attention to the viscosity effects in ACE. Change in the background electrolyte viscosity is unavoidable in ACE but numerous observations scattered throughout the literature have not been reviewed previously. This leads to an uncritical employment of correction factors that may or may not be appropriate in practice. Finally, we consider the ionic strength effects in ACE, too. Limitations of the current theories are also discussed and the tasks identified where open problems still prevail. Graphical Abstract A weak base (A) undergoes an acidic-basic equilibria (in blue) and migrates with an electrophoretic mobility of [Formula: see text]. Simultaneously, it interacts with a selector (sel) while the analyte-selector complex migrates with an electrophoretic mobility of [Formula: see text]. The strength of the interaction (in orange) is governed by the binding constant, K A , and the concentration of the selector, c sel . This all gives the analyte an effective mobility of [Formula: see text] and moves it out of the zero position (EOF; right top insert). The interaction of the positively charged analyte with the neutral selector slows down the analyte with increasing selector concentration (right bottom insert).

  11. Electrochemical Affinity Biosensors in Food Safety

    Directory of Open Access Journals (Sweden)

    Susana Campuzano

    2017-02-01

    Full Text Available Safety and quality are key issues of today’s food industry. Since the food chain is becoming more and more complex, powerful analytical methods are required to verify the performance of food safety and quality systems. Indeed, such methods require high sensitivity, selectivity, ability for rapid implementation and capability of automatic screening. Electroanalytical chemistry has, for decades, played a relevant role in food safety and quality assessment, taking more and more significance over time in the solution of analytical problems. At present, the implementation of electrochemical methods in the food is evident. This is in a large part due to the relevant results obtained by combining the attractive advantages of electrochemical transduction strategies (in terms of relatively simple hardware, versatility, interface with automatic logging and feasibility of application outside the laboratory environment with those from biosensors technology. Important examples of enzyme electrochemical biosensors are those dedicated to the determination of glucose, alcohol or cholesterol are important examples. In addition, other types of different electrochemical biosensing approaches have emerged strongly in the last years. Among these, the strategies involving affinity interactions have been shown to possess a large number of applications. Therefore, electrochemical immunosensors and DNA-based biosensors have been widely used to determine major and minor components in foodstuffs, providing sufficient data to evaluate food freshness, the quality of raw materials, or the origin of samples, as well as to determine a variety of compounds at trace levels related to food safety such as micotoxins, allergens, drugs residues or pathogen microorganisms. This review discusses some critical examples of the latest advances in this area, pointing out relevant methodologies related to the measurement techniques, including the use of nanostructured electrodes and

  12. Convulsant bicuculline modifies CNS muscarinic receptor affinity

    Directory of Open Access Journals (Sweden)

    Rodríguez de Lores Arnaiz Georgina

    2006-04-01

    Full Text Available Abstract Background Previous work from this laboratory has shown that the administration of the convulsant drug 3-mercaptopropionic acid (MP, a GAD inhibitor, modifies not only GABA synthesis but also binding of the antagonist [3H]-quinuclidinyl benzilate ([3H]-QNB to central muscarinic receptors, an effect due to an increase in affinity without modifications in binding site number. The cholinergic system has been implicated in several experimental epilepsy models and the ability of acetylcholine to regulate neuronal excitability in the neocortex is well known. To study the potential relationship between GABAergic and cholinergic systems with seizure activity, we analyzed the muscarinic receptor after inducing seizure by bicuculline (BIC, known to antagonize the GABA-A postsynaptic receptor subtype. Results We analyzed binding of muscarinic antagonist [3H]-QNB to rat CNS membranes after i.p. administration of BIC at subconvulsant (1.0 mg/kg and convulsant (7.5 mg/kg doses. Subconvulsant BIC dose failed to develop seizures but produced binding alteration in the cerebellum and hippocampus with roughly 40% increase and 10% decrease, respectively. After convulsant BIC dose, which invariably led to generalized tonic-clonic seizures, binding increased 36% and 15% to cerebellar and striatal membranes respectively, but decreased 12% to hippocampal membranes. Kd value was accordingly modified: with the subconvulsant dose it decreased 27% in cerebellum whereas it increased 61% in hippocampus; with the convulsant dose, Kd value decreased 33% in cerebellum but increased 85% in hippocampus. No change in receptor number site was found, and Hill number was invariably close to unity. Conclusion Results indicate dissimilar central nervous system area susceptibility of muscarinic receptor to BIC. Ligand binding was modified not only by a convulsant BIC dose but also by a subconvulsant dose, indicating that changes are not attributable to the seizure process

  13. Verifying the self-affine nature of regional seismicity using nonextensive Tsallis statistics

    CERN Document Server

    Minadakis, G; Stonham, J; Nomicos, C; Eftaxias, K

    2012-01-01

    The aspect of self-affine nature of faulting and fracture is widely documented from the data analysis of both field observations and laboratory experiments. In this direction, Huang and Turcotte have stated that the statistics of regional seismicity could be merely a macroscopic reflection of the physical processes in earthquake source, namely, the activation of a single fault is a reduced self-affine image of regional seismicity. This work verifies the aforementioned proposal. More precisely we show that the population of: (i) the earthquakes that precede of a significant event and occur around its the epicentre, and (ii) the "fracto-electromagnetic earthquakes" that are emerged during the fracture of strong entities distributed along the activated single fault sustaining the system follow the same statistics, namely, the relative cumulative number of earthquakes against magnitude. The analysis is mainly performed by means of a recently introduced nonextensive model for earthquake dynamics which leads to a G...

  14. Construcciones sociales del espacio turístico recreativo. Un estudio interpretativo sobre las prácticas recreativas en el Parque Nacional Molino de Flores Nezahualcóyotl, México

    Directory of Open Access Journals (Sweden)

    Rafael Hernández Espinosa

    2016-12-01

    Full Text Available Como cualquier otro espacio, los espacios turístico-recreativos se construyen socialmente, y dichas construcciones se generan en función de los significados, las prácticas e interacciones de quienes los visitan, principalmente. Desde esta premisa, este trabajo tiene como objetivo conocer las construcciones sociales, turísticas y recreativas de un destino en particular mediante la observación y el análisis de la experiencia, las prácticas y las interacciones sociales de sus visitantes. Los hallazgos se discuten a partir de un caso de estudio en el Parque Nacional Molino de Flores Nezahualcóyotl, México. A partir de las interacciones con el lugar y con los otros, el lugar es construido por los visitantes como un espacio de recreación familiar y de observación cultural, principalmente.

  15. Cianamida hidrogenada no raleio químico de flores e frutos de pessegueiros (Prunus persica, L. Batsch cv. Eldorado Hydrogen cyanamide on chemical thinning of peach-tree (Prunus persica, L. Batsch Flowers and fruits of Eldorado cultivar

    Directory of Open Access Journals (Sweden)

    Alexandre Couto Rodrigues

    1999-12-01

    Full Text Available O trabalho foi realizado com o objetivo de avaliar o efeito da cianamida hidrogenada (CH2N2 no raleio de flores e frutos de pessegueiros do cultivar Eldorado. Utilizaram-se plantas com idade de 6 anos, conduzidas sob a forma de vaso e espaçamento de 6,0 x 4,0m, localizadas no Centro Agropecuário da Palma - UFPel. Os tratamentos (0; 0,15; 0,3; 0,45 e 0,6% de CH2N2 foram pulverizados em cobertura sobre ramos selecionados aleatoriamente, até o início de gotejamento, quando 100% das flores encontravam-se totalmente abertas. O produto comercial utilizado foi o Dormex (52% de CH2N2. O delineamento experimental foi o inteiramente casualizado, com três repetições. As variáveis avaliadas foram: percentual de flores raleadas 36 dias após a aplicação do produto e percentual de frutos raleados, peso médio, coloração, diâmetro, firmeza da polpa e sólidos solúveis totais por ocasião da colheita. A maior intensidade de raleio de flores (50,96% foi obtida com utilização de 0,5% de CH2N2. Na percentagem de frutos raleados, observou-se valor máximo de 9,53%, utilizando-se CH2N2 a 0,6%. O peso dos frutos aumentou com o raleio químico, porém, este não interferiu nos sólidos solúveis totais, firmeza de polpa e índice de cor dos frutos.The objective of this research was to evaluate the effect of hydrogen cyanamide (CH2N2 on the chemical thinning of peach-tree flowers and fruits of Eldorado cultivar. Six-year plants localized at Agricultural Center of Palma - UFPel were used and conducted in vase with spacing of 6.0 x 4.0m. Treatments with 0, 0.15, 0.3, 0.45 and 0.6% of CH2N2 were sprayed on randomly selected shoots until drip point, when 100% of the flowers were totally blown. Dormex (52% of hydrogen cyanamide was the commercial chemical used. A completely randomized experimental design was used, with three replications. Percentage of flowers thinned 36 days after chemical application and percentage of thinned fruits, mean fruit weight

  16. Estudo de algumas caracteristicas bioquimicas de levedura isoladas de bebidas alcoolicas andinas e brasileiras e de amostras de flores, frutas, melaço e mosto de usinas de açucar e alcool

    OpenAIRE

    Carmen Josefina Contreras Castillo

    1990-01-01

    Resumo: O objetivo desta pesquisa foi estudar leveduras componentes da microbiota de bebidas alcoólicas, melaço e mosto de usinas de açúcar e álcool, frutas e flores e sua provável utilização em processos de fermentação. Foi estudado com especial ênfase as bebidas alcoólicas andinas provenientes da região montanhosa dos Andes situada em países como Peru, Chile, Bolívia e Colômbia que são até hoje elaboradas artesanalmentee. Foram isoladas 511 cepas de leveduras, sendo 132 provenientes de 45 a...

  17. Abundancia de colibríes y uso de flores en un bosque templado del sureste de México Hummingbird abundance and flowers use in a template forest from Southeast Mexico

    OpenAIRE

    Ruth Partida Lara; Enríquez, Paula L.; José Luis Rangel-Salazar; Carlos Lara; Miguel Martínez Ico

    2012-01-01

    La abundancia de los colibríes puede variar por la fenología de floración de las plantas de las que se alimentan. Sin embargo, la información sobre la interacción colibrí-flor es limitada en ambientes tropicales de montaña. En este estudio se evaluó la abundancia de colibríes con redes de niebla y se registró la fenología de floración mensual de las flores visitadas por los colibríes en tres ambientes (bosque de encino, de neblina y matorral) en la Reserva Ecológica Huitepec, Chiapas, México ...

  18. The sodium ion affinities of asparagine, glutamine, histidine and arginine

    Science.gov (United States)

    Wang, Ping; Ohanessian, Gilles; Wesdemiotis, Chrys

    2008-01-01

    The sodium ion affinities of the amino acids Asn, Gln, His and Arg have been determined by experimental and computational approaches (for Asn, His and Arg). Na+-bound heterodimers with amino acid and peptide ligands (Pep1, Pep2) were produced by electrospray ionization. From the dissociation kinetics of these Pep1-Na+-Pep2 ions to Pep1-Na+ and Pep2-Na+, determined by collisionally activated dissociation, a ladder of relative affinities was constructed and subsequently converted to absolute affinities by anchoring the relative values to known Na+ affinities. The Na+ affinities of Asn, His and Arg, were calculated at the MP2(full)/6-311+G(2d,2p)//MP2/6-31G(d) level of ab initio theory. The resulting experimental and computed Na+ affinities are in excellent agreement with one another. These results, combined with those of our previous studies, yield the sodium ion affinities of 18 out of the 20 [alpha]-amino acids naturally occurring in peptides and proteins of living systems.

  19. Tetrahydroprotoberberine alkaloids with dopamine and σ receptor affinity.

    Science.gov (United States)

    Gadhiya, Satishkumar; Madapa, Sudharshan; Kurtzman, Thomas; Alberts, Ian L; Ramsey, Steven; Pillarsetty, Nagavara-Kishore; Kalidindi, Teja; Harding, Wayne W

    2016-05-01

    Two series of analogues of the tetrahydroprotoberberine (THPB) alkaloid (±)-stepholidine that (a) contain various alkoxy substituents at the C10 position and, (b) were de-rigidified with respect to (±)-stepholidine, were synthesized and evaluated for affinity at dopamine and σ receptors in order to evaluate effects on D3 and σ2 receptor affinity and selectivity. Small n-alkoxy groups are best tolerated by D3 and σ2 receptors. Among all compounds tested, C10 methoxy and ethoxy analogues (10 and 11 respectively) displayed the highest affinity for σ2 receptors as well as σ2 versus σ1 selectivity and also showed the highest D3 receptor affinity. De-rigidification of stepholidine resulted in decreased affinity at all receptors evaluated; thus the tetracyclic THPB framework is advantageous for affinity at dopamine and σ receptors. Docking of the C10 analogues at the D3 receptor, suggest that an ionic interaction between the protonated nitrogen atom and Asp110, a H-bond interaction between the C2 phenol and Ser192, a H-bond interaction between the C10 phenol and Cys181 as well as hydrophobic interactions of the aryl rings to Phe106 and Phe345, are critical for high affinity of the compounds.

  20. Genetic Algorithm-based Affine Parameter Estimation for Shape Recognition

    Directory of Open Access Journals (Sweden)

    Yuxing Mao

    2014-06-01

    Full Text Available Shape recognition is a classically difficult problem because of the affine transformation between two shapes. The current study proposes an affine parameter estimation method for shape recognition based on a genetic algorithm (GA. The contributions of this study are focused on the extraction of affine-invariant features, the individual encoding scheme, and the fitness function construction policy for a GA. First, the affine-invariant characteristics of the centroid distance ratios (CDRs of any two opposite contour points to the barycentre are analysed. Using different intervals along the azimuth angle, the different numbers of CDRs of two candidate shapes are computed as representations of the shapes, respectively. Then, the CDRs are selected based on predesigned affine parameters to construct the fitness function. After that, a GA is used to search for the affine parameters with optimal matching between candidate shapes, which serve as actual descriptions of the affine transformation between the shapes. Finally, the CDRs are resampled based on the estimated parameters to evaluate the similarity of the shapes for classification. The experimental results demonstrate the robust performance of the proposed method in shape recognition with translation, scaling, rotation and distortion.

  1. Affinity Thresholds for Membrane Fusion Triggering by Viral Glycoproteins▿

    OpenAIRE

    Hasegawa, Kosei; Hu, Chunling; Nakamura, Takafumi; Marks, James D.; Russell, Stephen J.; Peng, Kah-Whye

    2007-01-01

    Enveloped viruses trigger membrane fusion to gain entry into cells. The receptor affinities of their attachment proteins vary greatly, from 10−4 M to 10−9 M, but the significance of this is unknown. Using six retargeted measles viruses that bind to Her-2/neu with a 5-log range in affinity, we show that receptor affinity has little impact on viral attachment but is nevertheless a key determinant of infectivity and intercellular fusion. For a given cell surface receptor density, there is an aff...

  2. Volatility Components, Affine Restrictions and Non-Normal Innovations

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Jacobs, Kris; Dorian, Christian;

    Recent work by Engle and Lee (1999) shows that allowing for long-run and short-run components greatly enhances a GARCH model's ability fit daily equity return dynamics. Using the risk-neutralization in Duan (1995), we assess the option valuation performance of the Engle-Lee model and compare...... models to four conditionally non-normal versions. As in Hsieh and Ritchken (2005), we find that non-affine models dominate affine models both in terms of fitting return and in terms of option valuation. For the affine models we find strong evidence in favor of the component structure for both returns...

  3. Notes on affine isometric actions of discrete groups

    CERN Document Server

    Neretin, Yu A

    1997-01-01

    Consider a lattice $\\Gamma$ in a group $G = SL_2(\\R), SO(1,n), SU(1,n)$, $SL_2(\\Q_p)$. We discuss actions of $\\Gamma$ by affine isometric transformations of Hilbert spaces. We show that for irreducible affine isometric action of $G$ its restriction to $\\Gamma$ is irreducible. We prove the existence of canonical irreducible affine isometric actions of $\\Gamma$ associated to actions of $\\Gamma$ on $\\R$- trees. Using such actions we construct irreducible representations of semigroup of probabilistic measures on diffeomorphisms of Riemann surfaces enumerated by the points of Thurston compactification of Teichmüller (Teichmuller) space.

  4. Moment-Based Method to Estimate Image Affine Transform

    Institute of Scientific and Technical Information of China (English)

    FENG Guo-rui; JIANG Ling-ge

    2005-01-01

    The estimation of affine transform is a crucial problem in the image recognition field. This paper resorted to some invariant properties under translation, rotation and scaling, and proposed a simple method to estimate the affine transform kernel of the two-dimensional gray image. Maps, applying to the original, produce some correlative points that can accurately reflect the affine transform feature of the image. Furthermore, unknown variables existing in the kernel of the transform are calculated. The whole scheme only refers to one-order moment,therefore, it has very good stability.

  5. Affine structures and a tableau model for E_6 crystals

    CERN Document Server

    Jones, Brant

    2009-01-01

    We provide the unique affine crystal structure for type E_6^{(1)} Kirillov-Reshetikhin crystals corresponding to the multiples of fundamental weights s Lambda_1, s Lambda_2, and s Lambda_6 for all s \\geq 1 (in Bourbaki's labeling of the Dynkin nodes, where 2 is the adjoint node). Our methods introduce a generalized tableaux model for classical highest weight crystals of type E and use the order three automorphism of the affine E_6^{(1)} Dynkin diagram. In addition, we provide a conjecture for the affine crystal structure of type E_7^{(1)} Kirillov-Reshetikhin crystals corresponding to the adjoint node.

  6. ODE/IM correspondence and modified affine Toda field equations

    CERN Document Server

    Ito, Katsushi

    2014-01-01

    We study the two-dimensional affine Toda field equations for affine Lie algebra $\\hat{\\mathfrak{g}}$ modified by a conformal transformation and the associated linear equations. In the conformal limit, the associated linear problem reduces to a (pseudo-)differential equation. For classical affine Lie algebra $\\hat{\\mathfrak{g}}$, we obtain a (pseudo-)differential equation corresponding to the Bethe equations for the Langlands dual of the Lie algebra $\\mathfrak{g}$, which were found by Dorey et al. in study of the ODE/IM correspondence.

  7. An improved affine projection algorithm for active noise cancellation

    Science.gov (United States)

    Zhang, Congyan; Wang, Mingjiang; Han, Yufei; Sun, Yunzhuo

    2017-08-01

    Affine projection algorithm is a signal reuse algorithm, and it has a good convergence rate compared to other traditional adaptive filtering algorithm. There are two factors that affect the performance of the algorithm, which are step factor and the projection length. In the paper, we propose a new variable step size affine projection algorithm (VSS-APA). It dynamically changes the step size according to certain rules, so that it can get smaller steady-state error and faster convergence speed. Simulation results can prove that its performance is superior to the traditional affine projection algorithm and in the active noise control (ANC) applications, the new algorithm can get very good results.

  8. Analysis of high affinity self-association by fluorescence optical sedimentation velocity analytical ultracentrifugation of labeled proteins: opportunities and limitations.

    Directory of Open Access Journals (Sweden)

    Huaying Zhao

    Full Text Available Sedimentation velocity analytical ultracentrifugation (SV is a powerful first-principle technique for the study of protein interactions, and allows a rigorous characterization of binding stoichiometry and affinities. A recently introduced commercial fluorescence optical detection system (FDS permits analysis of high-affinity interactions by SV. However, for most proteins the attachment of an extrinsic fluorophore is an essential prerequisite for analysis by FDS-SV. Using the glutamate receptor GluA2 amino terminal domain as a model system for high-affinity homo-dimerization, we demonstrate how the experimental design and choice of fluorescent label can impact both the observed binding constants as well as the derived hydrodynamic parameter estimates for the monomer and dimer species. Specifically, FAM (5,6-carboxyfluorescein was found to create different populations of artificially high-affinity and low-affinity dimers, as indicated by both FDS-SV and the kinetics of dimer dissociation studied using a bench-top fluorescence spectrometer and Förster Resonance Energy Transfer. By contrast, Dylight488 labeled GluA2, as well as GluA2 expressed as an EGFP fusion protein, yielded results consistent with estimates for unlabeled GluA2. Our study suggests considerations for the choice of labeling strategies, and highlights experimental designs that exploit specific opportunities of FDS-SV for improving the reliability of the binding isotherm analysis of interacting systems.

  9. Affinity (tropism) of caprine arthritis encephalitis virus for brain cells ...

    African Journals Online (AJOL)

    Affinity (tropism) of caprine arthritis encephalitis virus for brain cells. ... chain reaction (RTPCR) and transmission electron microscopy (TEM techniques). ... CAE virus infection of goat brain cells to that of HIV infection in humans thus suggesting ...

  10. Elective affinities and economic thought: 1870-1914

    Directory of Open Access Journals (Sweden)

    João Antônio de Paula

    2006-01-01

    Full Text Available This article seeks to demonstrate that the concept of "elective affinities" can be applied to the relations between economic thought, literature, and philosophy. Emphasis is given to Institutionalist thought, the German historical school, and neoclassical thought.

  11. ASIFT: An Algorithm for Fully Affine Invariant Comparison

    Directory of Open Access Journals (Sweden)

    Guoshen Yu

    2011-02-01

    Full Text Available If a physical object has a smooth or piecewise smooth boundary, its images obtained by cameras in varying positions undergo smooth apparent deformations. These deformations are locally well approximated by affine transforms of the image plane. In consequence the solid object recognition problem has often been led back to the computation of affine invariant image local features. The similarity invariance (invariance to translation, rotation, and zoom is dealt with rigorously by the SIFT method The method illustrated and demonstrated in this work, Affine-SIFT (ASIFT, simulates a set of sample views of the initial images, obtainable by varying the two camera axis orientation parameters, namely the latitude and the longitude angles, which are not treated by the SIFT method. Then it applies the SIFT method itself to all images thus generated. Thus, ASIFT covers effectively all six parameters of the affine transform.

  12. Dirac equation in gauge and affine-metric gravitation theories

    CERN Document Server

    Giachetta, G

    1995-01-01

    We show that the covariant derivative of Dirac fermion fields in the presence of a general linear connection on a world manifold is universal for Einstein's, gauge and affine-metric gravitation theories.

  13. REFINABLE DISTRIBUTIONS SUPPORTED ON SELF-AFFINE TILES

    Institute of Scientific and Technical Information of China (English)

    DaiXinrong

    2002-01-01

    In this paper,some conditions which assure the compactly supported refinable distributions supported on a self-affine tile to be Lebesgue-Stieltjes measures or absolutely continuous measures with respect to Lebesgue-Stieltjes measures are given.

  14. A thermodynamic approach to the affinity optimization of drug candidates.

    Science.gov (United States)

    Freire, Ernesto

    2009-11-01

    High throughput screening and other techniques commonly used to identify lead candidates for drug development usually yield compounds with binding affinities to their intended targets in the mid-micromolar range. The affinity of these molecules needs to be improved by several orders of magnitude before they become viable drug candidates. Traditionally, this task has been accomplished by establishing structure activity relationships to guide chemical modifications and improve the binding affinity of the compounds. As the binding affinity is a function of two quantities, the binding enthalpy and the binding entropy, it is evident that a more efficient optimization would be accomplished if both quantities were considered and improved simultaneously. Here, an optimization algorithm based upon enthalpic and entropic information generated by Isothermal Titration Calorimetry is presented.

  15. Taking Advantage: High Affinity B cells in the Germinal Center Have Lower Death Rates, But Similar Rates of Division Compared to Low Affinity Cells1

    OpenAIRE

    2009-01-01

    B lymphocytes producing high affinity antibodies (Abs) are critical for protection from extracellular pathogens, such as bacteria and parasites. The process by which high affinity B cells are selected during the immune response has never been elucidated. Though it has been shown that high affinity cells directly outcompete low affinity cells in the germinal center (GC)2, whether there are also intrinsic differences between these cells has not been addressed. It could be that higher affinity c...

  16. Affine A(1)3 N = 2 Monopole as the D Module and Affine ADHMN Sheaf

    Institute of Scientific and Technical Information of China (English)

    SONG Xiao-Shu; HOU Bo-Yu; GUO Yun-Dong; HOU Bo-Yuan; LING-HU Rong-Feng; L(U) Bing; CHENG Xin-Lu; YANG Xiang-Dong

    2008-01-01

    A Higgs-Yang-Mills monopole scattering spherical symmetrically Mong light cones is given. The left incoming anti-self-dual α plane fields are holomorphic, but the right outgoing SD fl plane fields are antiholomorphic, meanwhile the diffeomorphism symmetry is preserved with mutual inverse a/fine rapidity parameters μ and μ-1. The Dirac wave function scattering in this background also factorized respectively into the (anti)holomorphic amplitudes. The holomorphic anomaly is realized by the center term of a quasi Hopf algebra corresponding to an integrable conformal a/fine massive field. We find explicit Nahm transformation matrix (Fourier-Mukai transformation) between the Higgs YM BPS (fiat) bundles (D modules) and the affinized blow up ADHMN twistors (perverse sheafs). Thus we establish the algebra for the 't Hooft Hecke operators in the Hecke correspondence of the geometric Langfands program.

  17. Affinity purification of sequence-specific DNA binding proteins.

    OpenAIRE

    1986-01-01

    We describe a method for affinity purification of sequence-specific DNA binding proteins that is fast and effective. Complementary chemically synthesized oligodeoxynucleotides that contain a recognition site for a sequence-specific DNA binding protein are annealed and ligated to give oligomers. This DNA is then covalently coupled to Sepharose CL-2B with cyanogen bromide to yield the affinity resin. A partially purified protein fraction is combined with competitor DNA and subsequently passed t...

  18. Some Inequalities for Lp-mixed Affine Surface Area

    Institute of Scientific and Technical Information of China (English)

    ZHU Xian-yang

    2012-01-01

    In this paper,the concepts of the ith Lp-mixed affine surface area and Lp-polar curvature images are introduced,some new inequalities connecting these new notions with Lp-centroid bodies and p-Blaschke bodies are showed.Moreover,a Blaschke-Santaló type inequality for Lp-mixed affine surface area is established.Our results also imply the similar to the inequalities for Marcus-Lopes,Bergstrom and Ky Fan.

  19. Implementasi Kombinasi Caesar dan Affine Cipher untuk Keamanan Data Teks

    Directory of Open Access Journals (Sweden)

    Dian Rachmawati

    2015-11-01

    Full Text Available Petukaran data yang terjadi secara offline maupunonline sangat rentan dengan ancaman pencurian data. KombinasiCaesar dan Affine Cipher diharapkan mampu untuk menanganiisu keamanan data. Caesar Cipher bekerja denganmemanfaatkan pergeseran atau dikenal dengan shift ciphersementara Affine Cipher bekerja dengan menggunakan kunci duabuah bilangan integer. Kombinasi dua buah algoritma ini mampumengamankan data dan mengembalikan kembali ke bentukaslinya (plainteks, sehingga tidak menyebabkan integritasdatanya hilang. Kata Kunci—plainteks, cipherteks, Caesar cipher, Affinecipher.

  20. High affinity ligands for 'diazepam-insensitive' benzodiazepine receptors.

    Science.gov (United States)

    Wong, G; Skolnick, P

    1992-01-14

    Structurally diverse compounds have been shown to possess high affinities for benzodiazepine receptors in their 'diazepam-sensitive' (DS) conformations. In contrast, only the imidazobenzodiazepinone Ro 15-4513 has been shown to exhibit a high affinity for the 'diazepam-insensitive' (DI) conformation of benzodiazepine receptors. We examined a series of 1,4-diazepines containing one or more annelated ring systems for their affinities at DI and DS benzodiazepine receptors, several 1,4-diazepinone carboxylates including Ro 19-4603, Ro 16-6028 and Ro 15-3505 were found to possess high affinities (Ki approximately 2.6-20 nM) for DI. Nonetheless, among the ligands examined, Ro 15-4513 was the only substance with a DI/DS potency ratio approximately 1; other substances had ratios ranging from 13 to greater than 1000. Ligands with high to moderate affinities at DI were previously classified as partial agonists, antagonists, or partial inverse agonists at DS benzodiazepine receptors, but behaved as 'GABA neutral' (antagonist) substances at DI. The identification of several additional high affinity ligands at DI benzodiazepine receptors may be helpful in elucidating the pharmacological and physiological importance of these sites.

  1. Affinity Solvents for Intensified Organics Extraction: Development Challenges and Prospects

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In most organics extraction processes, the commonly used solvents employ solely physical interactions. Therefore, for the recovery and purification of products from complex mixtures, the selectivity and/or capacity of classical solvents towards the desired solutes is usually insufficient, enforcing the need for complex and thus expensive separation schemes. Significant simplification and cost-reduction can be achieved when affinity solvents would be available that are able to recognize the solutes of interest by their molecular structure. The main development challenges to establish such affinity solvents are: Selection and incorporation of molecular recognition and complexation capabilities; Evaluation of extraction capabilities; Efficient recovery and recycling of the affinity solvents; Implementation in industrial extraction equipment. This paper presents how these development challenges are addressed at the University of Twente, going all the way from affinity solvent design and synthesis, via high throughput screening and characterization up to pilot plant evaluation. Essential in the successful development of affinity solvents are structural cooperations with molecular chemists and custom synthesis companies for their design and synthesis. The various aspects are illustrated by several examples where newly developed environmentally benign affinity solvents appeared able to create major breakthroughs. The applications addressed involve oxygenates, sugars, and pharmaceutical ingredients, such as optical isomers and biomolecules.

  2. Reconstitution of high-affinity opioid agonist binding in brain membranes

    Energy Technology Data Exchange (ETDEWEB)

    Remmers, A.E.; Medzihradsky, F. (Univ. of Michigan Medical School, Ann Arbor (United States))

    1991-03-15

    In synaptosomal membranes from rat brain cortex, the {mu} selective agonist ({sup 3}H)dihydromorphine in the absence of sodium, and the nonselective antagonist ({sup 3}H)naltrexone in the presence of sodium, bound to two populations of opioid receptor sites with K{sub d} values of 0.69 and 8.7 nM for dihydromorphine, and 0.34 and 5.5 nM for naltrexone. The addition of 5 {mu}M guanosine 5{prime}-({gamma}-thio)triphosphate (GTP({gamma}S)) strongly reduced high-affinity agonist but not antagonist binding. Exposure of the membranes to high pH reduced the number of GTP({gamma}-{sup 35}S) binding sites by 90% and low K{sub m}, opioid-sensitive GTPase activity by 95%. In these membranes, high-affinity agonist binding was abolished and modulation of residual binding by GTP({gamma}S) was diminished. Alkali treatment of the glioma cell membranes prior to fusion inhibited most of the low K{sub m} GTPase activity and prevented the reconstitution of agonist binding. The results show that high-affinity opioid agonist binding reflects the ligand-occupied receptor - guanine nucleotide binding protein complex.

  3. Colony stimulating factor (CSF) from human leukemic urine: affinity chromatography and isoelectric focusing.

    Science.gov (United States)

    Kellar, K L; Vogler, W R; Kinkade, J M

    1975-12-01

    Biological activities associated with colony-stimulating factor (CSF) from human leukemic urine were found to be selectively retained on an affinity adsorbent of Con A-Sepharose. Elution of activity was achieved using a linear gradient of eith alpha-methyl-D-mannopyranoside (alphaMM) or alpha-methyl-D-glucopyranoside (alphaMG), and resulted in significant increases in specific biological activity. Rechromatography of appropriate fractions indicated that retention of CSF activities was not artifactual. Pretreatment of the affinity matrix with alphaMM completely inhibited binding of CSF. Affinity chromatography of CSF on a Blue Dextran-Sepharose adsorbent was found to be an effective method for removing albumin, a major protein contaminant in urinary preparations. Treatment of CSF with neuraminidase had no effect on its in vitro activity; however, such treatment resulted in an increase in the isoelectric point of CSF from pH 3.5 to pH 4.7, as determined using both sucrose and polyacrylamide gel stabilized pH gradients. Relatively broad regions of biological activity were observed following isoelectric focusing of both neuraminidase-treated and untreated CSF, suggesting that activity was associated with a heterogeneous/polydisperse population of molecular species.

  4. Lapa vermelha IV Hominid 1: morphological affinities of the earliest known American

    Directory of Open Access Journals (Sweden)

    Neves Walter A.

    1999-01-01

    Full Text Available Several studies concerning the extra-continental morphological affinities of Paleo-Indian skeletons, carried out independently in South and North America, have indicated that the Americas were first occupied by non-Mongoloids that made their way to the New World through the Bering Strait in ancient times. The first South Americans show a clear resemblance to modern South Pacific and African populations, while the first North Americans seem to be at an unresolved morphological position between modern South Pacific and Europeans. In none of these analyses the first Americans show any resemblance to either northeast Asians or modern native Americans. So far, these studies have included affirmed and putative early skeletons thought to date between 8,000 and 10,000 years B.P. In this work the extra-continental morphological affinities of a Paleo-Indian skeleton well dated between 11,000 and 11,500 years B.P. (Lapa Vermelha IV Hominid 1, or "Luzia" is investigated, using as comparative samples Howells' (1989 world-wide modern series and Habgood's (1985 Old World Late Pleistocene fossil hominids. The comparison between Lapa Vermelha IV Hominid 1 and Howells' series was based on canonical variate analysis, including 45 size-corrected craniometric variables, while the comparison with fossil hominids was based on principal component analysis, including 16 size-corrected variables. In the first case, Lapa Vermelha IV Hominid 1 exhibited an undisputed morphological affinity firstly with Africans and secondly with South Pacific populations. In the second comparison, the earliest known American skeleton had its closest similarities with early Australians, Zhoukoudian Upper Cave 103, and Taforalt 18. The results obtained clearly confirm the idea that the Americas were first colonized by a generalized Homo sapiens population which inhabited East Asia in the Late Pleistocene, before the definition of the classic Mongoloid morphology.

  5. Genetic affinities of Helicobacter pylori isolates from ethnic Arabs in Kuwait

    Directory of Open Access Journals (Sweden)

    Albert M John

    2010-07-01

    Full Text Available Abstract Helicobacter pylori is one of the most genetically diverse of bacterial species, and since the 5'-end of cagA gene and the middle allele of vacA gene of H. pylori from different populations exhibit considerable polymorphisms, these sequence diversities were used to gain insights into the genetic affinities of this gastric pathogen from different populations. Because the genetic affinity of Arab strains from the Arabian Gulf is not known, we carried out genetic analysis based on sequence diversities of the cagA and the vacA genes of H. pylori from 9 ethnic Arabs in Kuwait. The analysis showed that the Kuwaiti isolates are closely related to the Indo-European group of strains, although some strains have a tendency to form a separate cluster close to the Indo- European group, but clearly distinct from East Asian strains. However, these results need to be confirmed by analyses of neutral markers (house-keeping genes in a multi-locus sequence typing [MLST] platform. The profiling of virulence-associated genes may have resulted from ecologically distinct populations due to human migration and geographical separation over long periods of time.

  6. Supervised Machine Learning Methods Applied to Predict Ligand- Binding Affinity.

    Science.gov (United States)

    Heck, Gabriela S; Pintro, Val O; Pereira, Richard R; de Ávila, Mauricio B; Levin, Nayara M B; de Azevedo, Walter F

    2017-01-01

    Calculation of ligand-binding affinity is an open problem in computational medicinal chemistry. The ability to computationally predict affinities has a beneficial impact in the early stages of drug development, since it allows a mathematical model to assess protein-ligand interactions. Due to the availability of structural and binding information, machine learning methods have been applied to generate scoring functions with good predictive power. Our goal here is to review recent developments in the application of machine learning methods to predict ligand-binding affinity. We focus our review on the application of computational methods to predict binding affinity for protein targets. In addition, we also describe the major available databases for experimental binding constants and protein structures. Furthermore, we explain the most successful methods to evaluate the predictive power of scoring functions. Association of structural information with ligand-binding affinity makes it possible to generate scoring functions targeted to a specific biological system. Through regression analysis, this data can be used as a base to generate mathematical models to predict ligandbinding affinities, such as inhibition constant, dissociation constant and binding energy. Experimental biophysical techniques were able to determine the structures of over 120,000 macromolecules. Considering also the evolution of binding affinity information, we may say that we have a promising scenario for development of scoring functions, making use of machine learning techniques. Recent developments in this area indicate that building scoring functions targeted to the biological systems of interest shows superior predictive performance, when compared with other approaches. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  7. AID activity in B cells strongly correlates with polyclonal antibody affinity maturation in-vivo following pandemic 2009-H1N1 vaccination in humans.

    Science.gov (United States)

    Khurana, Surender; Frasca, Daniela; Blomberg, Bonnie; Golding, Hana

    2012-09-01

    The role of Activation-Induced Cytidine Deaminase (AID) in somatic hypermutation and polyclonal antibody affinity maturation has not been shown for polyclonal responses in humans. We investigated whether AID induction in human B cells following H1N1pdm09 vaccination correlated with in-vivo antibody affinity maturation against hemagglutinin domains in plasma of young and elderly individuals. AID was measured by qPCR in B cells from individuals of different ages immunized with the H1N1pdm09 influenza vaccine. Polyclonal antibody affinity in human plasma for the HA1 and HA2 domains of the H1N1pdm09 hemagglutinin was measured by antibody-antigen complex dissociation rates using real time kinetics in Surface Plasmon Resonance. Results show an age-related decrease in AID induction in B cells following H1N1pdm09 vaccination. Levels of AID mRNA before vaccination and fold-increase of AID mRNA expression after H1N1pdm09 vaccination directly correlated with increase in polyclonal antibody affinity to the HA1 globular domain (but not to the conserved HA2 stalk). In the younger population, significant affinity maturation to the HA1 globular domain was observed, which associated with initial levels of AID and fold-increase in AID after vaccination. In some older individuals (>65 yr), higher affinity to the HA1 domain was observed before vaccination and H1N1pdm09 vaccination resulted in minimal change in antibody affinity, which correlated with low AID induction in this age group. These findings demonstrate for the first time a strong correlation between AID induction and in-vivo antibody affinity maturation in humans. The ability to generate high affinity antibodies could have significant impact on the elucidation of age-specific antibody responses following vaccination and eventual clinical efficacy and disease outcome.

  8. Affine kinematics in planar fibrous connective tissues: an experimental investigation.

    Science.gov (United States)

    Jayyosi, C; Affagard, J-S; Ducourthial, G; Bonod-Bidaud, C; Lynch, B; Bancelin, S; Ruggiero, F; Schanne-Klein, M-C; Allain, J-M; Bruyère-Garnier, K; Coret, M

    2017-03-29

    The affine transformation hypothesis is usually adopted in order to link the tissue scale with the fibers scale in structural constitutive models of fibrous tissues. Thanks to the recent advances in imaging techniques, such as multiphoton microscopy, the microstructural behavior and kinematics of fibrous tissues can now be monitored at different stretching within the same sample. Therefore, the validity of the affine hypothesis can be investigated. In this paper, the fiber reorientation predicted by the affine assumption is compared to experimental data obtained during mechanical tests on skin and liver capsule coupled with microstructural imaging using multiphoton microscopy. The values of local strains and the collagen fibers orientation measured at increasing loading levels are used to compute a theoretical estimation of the affine reorientation of collagen fibers. The experimentally measured reorientation of collagen fibers during loading could not be successfully reproduced with this simple affine model. It suggests that other phenomena occur in the stretching process of planar fibrous connective tissues, which should be included in structural constitutive modeling approaches.

  9. Selective affinity of pirenzepine analogues for subtypes of muscarinic receptors

    Energy Technology Data Exchange (ETDEWEB)

    Stubbins, J.F.; Smith, J.D.; Liu, W.S.; Gulya, K.; Yamamura, H.I.

    1986-03-05

    Pirenzepine (PZ), telenzepine (TZ) and quinuclidinyl xanthene-9-carboxylate (QNX) are antimuscarinic agents containing a tricyclic ring system and a basic side chain that have been reported to have selective affinity for the M/sub 1/ subtype of receptor. They have prepared and examined seven new PZ analogues containing modifications in either the tricyclic ring system, the side-chain, or both. Affinity for M/sub 1/ type receptors was determined by displacement of specifically-bound (/sup 3/H)PZ from rat cerebral cortex homogenates. Affinity for M/sub 2/ type receptors was measured on rat heart homogenate using (/sup 3/H)(-)quinuclidinyl benzilate. The ratio of the K/sub i/'s for M/sub 1/ and M/sub 2/ receptors were calculated and compared to PZ. All of the compounds had a higher affinity for M/sub 1/ than M/sub 2/ receptors. Three of the compounds were comparable to PZ in selectivity, but the more selective compounds had a weaker affinity for M/sub 1/ receptors. TZ and QNX were less selective than PZ.

  10. Protein purification by aminosquarylium cyanine dye-affinity chromatography.

    Science.gov (United States)

    Silva, M S; Graça, V C; Reis, L V; Santos, P F; Almeida, P; Queiroz, J A; Sousa, F

    2013-12-01

    The most selective purification method for proteins and other biomolecules is affinity chromatography. This method is based on the unique biological-based specificity of the biomolecule-ligand interaction and commonly uses biological ligands. However, these ligands may present some drawbacks, mainly because of their cost and lability. Dye-affinity chromatography overcomes the limitations of biological ligands and is widely used owing to the low cost of synthetic dyes and to their resistance to biological and chemical degradation. In this work, immobilized aminosquarylium cyanine dyes are used in order to exploit affinity interactions with standard proteins such as lysozyme, α-chymotrypsin and trypsin. These studies evaluate the affinity interactions occurring between the immobilized ligand and the different proteins, as a reflection of the sum of several molecular interactions, namely ionic, hydrophobic and van der Waals, spread throughout the structure, in a defined spatial manner. The results show the possibility of using an aminosquarylium cyanine dye bearing a N-hexyl pendant chain, with a ligand density of 1.8 × 10(-2) mmol of dye/g of chromatographic support, to isolate lysozyme, α-chymotrypsin and trypsin from a mixture. The application of a decreasing ammonium sulfate gradient resulted in the recovery of lysozyme in the flowthrough. On the other hand, α-chymotrypsin and trypsin were retained, involving different interactions with the ligand. In conclusion, this study demonstrates the potential applicability of ligands such as aminosquarylium cyanine dyes for the separation and purification of proteins by affinity chromatography.

  11. The proton affinities of saturated and unsaturated heterocyclic molecules

    Science.gov (United States)

    Kabli, Samira; van Beelen, Eric S. E.; Ingemann, Steen; Henriksen, Lars; Hammerum, Steen

    2006-03-01

    The proton affinities derived from G3-calculations of 23 five-membered ring heteroaromatic molecules agree well with the experimentally determined values available in the literature. The calculated local proton affinities show that the principal site of protonation of the heteroaromatic compounds examined is an atom of the ring, carbon when there is only one heteroatom in the ring, and nitrogen where there are two or more heteroatoms. The experimental proton affinities of non-aromatic cyclic ethers, amines and thioethers are also in excellent agreement with the calculated values, with two exceptions (oxetane, N-methylazetidine). The literature proton affinities of the four simple cyclic ethers, oxetane, tetrahydrofuran, tetrahydropyran and oxepane were confirmed by Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry, in order to examine the disagreement between the values predicted by extrapolation or additivity for tetrahydrofuran and tetrahydropyran and those determined by experiment and by calculation. The proton affinity differences between the pairs tetrahydropyran/1,4-dioxane, piperidine/morpholine and related compounds show that introduction of an additional oxygen atom in the ring considerably lowers the basicity.

  12. Queima das flores e podridão parda em pessegueiro sob sistema de cultivo orgânico Blossom blight and brown rot on organic peach production system

    Directory of Open Access Journals (Sweden)

    Cláudio Keske

    2010-08-01

    Full Text Available A queima das flores e a podridão parda, causadas por Monilinia fructicola, são as doenças mais importantes na cultura do pessegueiro. Este estudo teve como objetivo verificar a incidência de queima das flores e podridão parda latente em frutos verdes e na colheita sob condições naturais de infecção, em relação à posição dos ramos em pomar com cultivares de pessegueiro sob sistema de cultivo orgânico. As avaliações foram realizadas com as cultivares 'Aurora', 'Flordaking', 'Marli' e 'Della Nona' em 2006, e 'Aurora' e 'Marli' em 2007 e 2008 e conduzidas em sistema orgânico em Rio do Sul, Santa Catarina (SC. Foram monitorados semanalmente os conídios do patógeno em armadilhas tipo "cata-vento". A incidência média da doença na floração foi de 0,8 ('Della Nona' a 19,1% ('Marli'. A incidência na colheita foi de 15,4('Della Nona' a 65,7% ('Flordaking'. Correlações positivas e significativas foram verificadas entre número de conídios e fases fenológicas variando de 0,67 ('Flordaking a 0,99 ('Aurora'. A posição do ramo no pomar, na linha ou na entrelinha não influenciou a incidência da doença nas flores e nos frutos. A maior concentração de conídios foi observada na fase de maturação dos frutos.The blossom blight and brown rot caused by Monilinia fructicola are the most important diseases of peach tree. This study aimed to verify the incidence of the blossom blight on flowers and latent brown rot in green fruits, and at harvest under natural infection, in relation to the position of branches in the orchard with peach cultivars under organic system. The evaluations were carried out with the cultivars 'Aurora', 'Flordaking', 'Marli' and 'Della Nona' in 2006, 'Aurora' and 'Marli' in 2007 and 2008 and conducted in an organic syste m in Rio do Sul, SC. Conidia were monitored weekly by "winddriven" traps. At flowering the average incidence was 0.8 ('Della Nona' to 19.1% ('Marli'. The incidence at harvest was 15

  13. Pistillate Flower Abcission Symptoms of ‘Serr’ Walnut (Juglans RegiaL. Sintomatología del Aborto en flores Pistiladas de Nogal (Juglans regiaL. ‘Serr’

    Directory of Open Access Journals (Sweden)

    Cristián González R

    2008-06-01

    Full Text Available Pistillate flower abscission (PFA severely affects walnut (Juglans regia L. production, mainly of the cultivar ‘Serr’. A study on symptoms of flower abortion in walnut ‘Serr’, induced by excess or lack of pollen, was carried out following the evolution of flowers and peduncles. Hand pollinated flowers, with different pollen concentrations: 0, 1, 5, 25, 50 and 100% pollen diluted (w/w in talcum powder, showed external and internal abortion symptoms. External symptoms were recorded directly from the tree, while for internal symptoms, flower excisions stained with blue Toluidin-O at 0.05%, were analyzed under an optical microscope. Excess pollen abortion produced flowers with rapid damage. The growth rate was very low, involucre brightness was lost and the stigma turned necrotic, in contrast to the flower aborted from lack of pollen. Normal flowers continued growing to fruit harvest, without losing brightness. Excess pollen abortion induced flower drop, with or without attached peduncle. Two separation zones can be present: the distal and proximal areas of the peduncle. Peduncle scars allowed for differentiating abortion induced from excess or lack of pollen, or other reasons.El aborto en flores postiladas (PFA por exceso de polen que afecta al nogal (Juglans regia L., disminuye considerablemente la producción de nueces, principalmente en el cultivar ‘Serr’. Se estudió la sintomatología del aborto por exceso y falta de polinización en flores y pedúnculo de este cultivar. Para esto se realizó polinización manual, utilizando diferentes concentraciones de polen sobre flores en diferentes estados de receptividad. Las concentraciones se obtuvieron mediante diluciones (peso/peso de polen combinado con talco. Las concentraciones utilizadas fueron 0; 1; 5; 25; 50 y 100% de polen. Se observó la sintomatología externa e interna de la flor, mediante apreciación visual en el árbol y a través de cortes longitudinales en la flor para

  14. Viabilidade dos grãos de pólen de flores de pinheira (Annona squamosa em diferentes horários Viability of the sugar apple (Annona squamosa pollen grains at different hours of the day

    Directory of Open Access Journals (Sweden)

    Silvia Nietsche

    2009-04-01

    Full Text Available No manejo do cultivo da pinha (Annona squamosa, a polinização artificial é uma prática preconizada para, obter maior pegamento dos frutos bem como uniformização do formato dos mesmos. Nesse sentido, conduziu-se este trabalho, com o objetivo de avaliar a viabilidade dos grãos de pólen de flores de pinheira em diferentes horários de coleta. O pólen foi obtido a partir de flores no estádio funcionalmente estaminada. Foram avaliados oito horários de coleta de pólen: zero hora, 1 hora, 2 horas, 3 horas, 4 horas, 5 horas, 6 horas e 7 horas da manhã. Foi utilizado meio de cultura padrão para germinação de pólen, com concentração de 10% de sacarose. As flores foram coletadas nos horários estabelecidos e os grãos de pólen foram retirados das anteras com auxílio de um pincel número 2 e em seguida inoculados em placas de Petri contendo o meio de cultura. O delineamento experimental foi inteiramente casualizado com quatro repetições, sendo cada parcela experimental constituída por duas placas Petri. Foram contados 100 grãos de pólen por placa. Após 6 horas de inoculação, os grãos de pólen foram visualizados sob lupa. Foram considerados germinados os grãos de pólen que possuíam tubo polínico com tamanho igual ou superior ao diâmetro do próprio pólen. Não foram observadas diferenças significativas entre o horário de coleta dos grãos de pólen. A percentagem média da germinação variou de 46,75% a 53,62% dos grãos de pólen germinados.In the management of the sugar apple (Annona squamosa crop, the artificial pollination is a preconized practice to obtain higher establishment of the fruits as well as their standardization. This study was carried out to evaluate the viability of sugar apple pollen grains at different collecting times. The pollens were obtained from the flowers at the functional staminate stage. The pollen grains were collected every hour, starting from 00:00am and ending at 07:00am, totalizing 8

  15. Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells.

    Science.gov (United States)

    Anderson, Shannon M; Khalil, Ashraf; Uduman, Mohamed; Hershberg, Uri; Louzoun, Yoram; Haberman, Ann M; Kleinstein, Steven H; Shlomchik, Mark J

    2009-12-01

    B lymphocytes producing high-affinity Abs are critical for protection from extracellular pathogens, such as bacteria and parasites. The process by which high-affinity B cells are selected during the immune response has never been elucidated. Although it has been shown that high-affinity cells directly outcompete low-affinity cells in the germinal center (GC), whether there are also intrinsic differences between these cells has not been addressed. It could be that higher affinity cells proliferate more rapidly or are more likely to enter cell cycle, thereby outgrowing lower affinity cells. Alternatively, higher affinity cells could be relatively more resistant to cell death in the GC. By comparing high- and low-affinity B cells for the same Ag, we show here that low-affinity cells have an intrinsically higher death rate than do cells of higher affinity, even in the absence of competition. This suggests that selection in the GC reaction is due at least in part to the control of survival of higher affinity B cells and not by a proliferative advantage conferred upon these cells compared with lower affinity B cells. Control over survival rather than proliferation of low- and high-affinity B cells in the GC allows greater diversity not only in the primary response but also in the memory response.

  16. Mesozooplankton affinities in a recovering freshwater estuary

    Science.gov (United States)

    Chambord, Sophie; Maris, Tom; Colas, Fanny; Van Engeland, Tom; Sossou, Akoko-C.; Azémar, Frédéric; Le Coz, Maïwen; Cox, Tom; Buisson, Laetitia; Souissi, Sami; Meire, Patrick; Tackx, Michèle

    2016-08-01

    for their decline. Water quality improvement in the freshwater Scheldt estuary has led to environmental, post-heavy polluted conditions, under which no data on zooplankton populations in this estuary were available. This has indicated a plasticity in the temperature tolerance of E. affinis.

  17. A fast quantum algorithm for the affine Boolean function identification

    Science.gov (United States)

    Younes, Ahmed

    2015-02-01

    Bernstein-Vazirani algorithm (the one-query algorithm) can identify a completely specified linear Boolean function using a single query to the oracle with certainty. The first aim of the paper is to show that if the provided Boolean function is affine, then one more query to the oracle (the two-query algorithm) is required to identify the affinity of the function with certainty. The second aim of the paper is to show that if the provided Boolean function is incompletely defined, then the one-query and the two-query algorithms can be used as bounded-error quantum polynomial algorithms to identify certain classes of incompletely defined linear and affine Boolean functions respectively with probability of success at least 2/3.

  18. Single-cell measurement of red blood cell oxygen affinity

    CERN Document Server

    Caprio, Di; Higgins, John M; Schonbrun, Ethan

    2015-01-01

    Oxygen is transported throughout the body by hemoglobin in red blood cells. While the oxygen affinity of blood is well understood and is routinely assessed in patients by pulse oximetry, variability at the single-cell level has not been previously measured. In contrast, single-cell measurements of red blood cell volume and hemoglobin concentration are taken millions of times per day by clinical hematology analyzers and are important factors in determining the health of the hematologic system. To better understand the variability and determinants of oxygen affinity on a cellular level, we have developed a system that quantifies the oxygen saturation, cell volume and hemoglobin concentration for individual red blood cells in high-throughput. We find that the variability in single-cell saturation peaks at an oxygen partial pressure of 2.5%, which corresponds to the maximum slope of the oxygen-hemoglobin dissociation curve. In addition, single-cell oxygen affinity is positively correlated with hemoglobin concentr...

  19. Enhancing Community Detection By Affinity-based Edge Weighting Scheme

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Andy [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sanders, Geoffrey [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Henson, Van [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vassilevski, Panayot [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-05

    Community detection refers to an important graph analytics problem of finding a set of densely-connected subgraphs in a graph and has gained a great deal of interest recently. The performance of current community detection algorithms is limited by an inherent constraint of unweighted graphs that offer very little information on their internal community structures. In this paper, we propose a new scheme to address this issue that weights the edges in a given graph based on recently proposed vertex affinity. The vertex affinity quantifies the proximity between two vertices in terms of their clustering strength, and therefore, it is ideal for graph analytics applications such as community detection. We also demonstrate that the affinity-based edge weighting scheme can improve the performance of community detection algorithms significantly.

  20. Affinity chromatography of acetylcholinesterase. The importance of hydrophobic interactions.

    Science.gov (United States)

    Massoulié, J; Bon, S

    1976-09-15

    An easily prepared affinity column for acetylcholinesterase is described, which may be operated at ionic strength high enough to prevent aggregation of the asymmetric forms of the enzyme. Specific elution by tetraethylammonium or decamethonium was quantitative. The performance of this column is comparable to that of the column described by Dudai and Silman. It is shown that the hexyl 'spacer arm' strongly participates in the enzyme binding and that its replacement with the more hydrophilic spermine chain lowers the affinity. The hexyl chain itself is shown to bind acetylcholinesterase, although with lower affinity and capacity than the complete column. This binding is also partly reversed by inhibitors. Such hydrophobic columns bind the native asymmetric forms of the enzyme more strongly than the lytic globular ones. The aromatic quaternary ligang inhibits Electrophorus but not Torpedo acetylcholinesterase; therefore the column does not retain the Torpedo enzyme. Differences in Km between acetylcholinesterases of the two species also point to differences in their active sites.

  1. Fast Affinity Propagation Clustering based on Machine Learning

    Directory of Open Access Journals (Sweden)

    Shailendra Kumar Shrivastava

    2013-01-01

    Full Text Available Affinity propagation (AP was recently introduced as an un-supervised learning algorithm for exemplar based clustering. In this paper a novel Fast Affinity Propagation clustering Approach based on Machine Learning (FAPML has been proposed. FAPML tries to put data points into clusters based on the history of the data points belonging to clusters in early stages. In FAPML we introduce affinity learning constant and dispersion constant which supervise the clustering process. FAPML also enforces the exemplar consistency and one of 'N constraints. Experiments conducted on many data sets such as Olivetti faces, Mushroom, Documents summarization, Thyroid, Yeast, Wine quality Red, Balance etc. show that FAPML is up to 54 % faster than the original AP with better Net Similarity.

  2. The Affine Structure of Gravitational Theories: Symplectic Groups and Geometry

    CERN Document Server

    Capozziello, Salvatore; De Laurentis, Mariafelicia

    2014-01-01

    We give a geometrical description of gravitational theories from the viewpoint of symmetries and affine structure. We show how gravity, considered as a gauge theory, can be consistently achieved by the nonlinear realization of the conformal-affine group in an indirect manner: due the partial isomorphism between $CA\\left( 3,1\\right) $ and the centrally extended $Sp\\left( 8\\right) $, we perform a nonlinear realization of the centrally extended (CE)$Sp\\left( 8\\right) $ in its semi-simple version. In particular, starting from the bundle structure of gravity, we derive the conformal-affine Lie algebra and then, by the non-linear realization, we define the coset field transformations, the Cartan forms and the inverse Higgs constraints. Finally we discuss the geometrical Lagrangians where all the information on matter fields and their interactions can be contained.

  3. k-Schur functions and affine Schubert calculus

    CERN Document Server

    Lam, Thomas; Morse, Jennifer; Schilling, Anne; Shimozono, Mark; Zabrocki, Mike

    2014-01-01

    This book gives an introduction to the very active field of combinatorics of affine Schubert calculus, explains the current state of the art, and states the current open problems. Affine Schubert calculus lies at the crossroads of combinatorics, geometry, and representation theory. Its modern development is motivated by two seemingly unrelated directions. One is the introduction of k-Schur functions in the study of Macdonald polynomial positivity, a mostly combinatorial branch of symmetric function theory. The other direction is the study of the Schubert bases of the (co)homology of the affine Grassmannian, an algebro-topological formulation of a problem in enumerative geometry. This is the first introductory text on this subject. It contains many examples in Sage, a free open source general purpose mathematical software system, to entice the reader to investigate the open problems. This book is written for advanced undergraduate and graduate students, as well as researchers, who want to become familiar with ...

  4. Generalized Rogers-Ramanujan identities for twisted affine algebras

    Science.gov (United States)

    Genish, Arel; Gepner, Doron

    2017-07-01

    The characters of parafermionic conformal field theories are given by the string functions of affine algebras, which are either twisted or untwisted algebras. Expressions for these characters as generalized Rogers-Ramanujan algebras have been established for the untwisted affine algebras. However, we study the identities for the string functions of the twisted affine Lie algebras. A conjecture for the string functions was proposed by Hatayama et al., for the unit fields, which expresses the string functions as Rogers-Ramanujan type sums. Here we propose to check the Hatayama et al. conjecture, using Lie algebraic theoretic methods. We use Freudenthal’s formula, which we computerized, to verify the identities for all the algebras at low rank and low level. We find complete agreement with the conjecture.

  5. Super-Affine Hierarchies and their Poisson Embeddings

    CERN Document Server

    Toppan, F

    1998-01-01

    The link between (super)-affine Lie algebras as Poisson brackets structures and integrable hierarchies provides both a classification and a tool for obtaining superintegrable hierarchies. The lack of a fully systematic procedure for constructing matrix-type Lax operators, which makes the supersymmetric case essentially different from the bosonic counterpart, is overcome via the notion of Poisson embeddings (P.E.), i.e. Poisson mappings relating affine structures to conformal structures (in their simplest version P.E. coincide with the Sugawara construction). A full class of hierarchies can be recovered by using uniquely Lie-algebraic notions. The group-algebraic properties implicit in the super-affine picture allow a systematic derivation of reduced hierarchies by imposing either coset conditions or hamiltonian constraints (or possibly both).

  6. Properties of the Affine Invariant Ensemble Sampler in high dimensions

    CERN Document Server

    Huijser, David; Brewer, Brendon J

    2015-01-01

    We present theoretical and practical properties of the affine-invariant ensemble sampler Markov chain Monte Carlo method. In high dimensions the affine-invariant ensemble sampler shows unusual and undesirable properties. We demonstrate this with an $n$-dimensional correlated Gaussian toy problem with a known mean and covariance structure, and analyse the burn-in period. The burn-in period seems to be short, however upon closer inspection we discover the mean and the variance of the target distribution do not match the expected, known values. This problem becomes greater as $n$ increases. We therefore conclude that the affine-invariant ensemble sampler should be used with caution in high dimensional problems. We also present some theoretical results explaining this behaviour.

  7. REPRESENTATIONS OF AFFINE HECKE ALGEBRAS OF TYPE G2

    Institute of Scientific and Technical Information of China (English)

    Xi Nanhua

    2009-01-01

    Let k be a field and q a nonzero element in k such that the square roots of q are in k.We use Hq to denote an affine Hecke algebra over k of type G2 with parameter q.The purpose of this paper is to study representations of Hq by using based rings of two-sided cells of an affine Weyl group W of type G2.We shall give the classification of irreducible representations of Hq.We also remark that a calculation in [11] actually shows that Theorem 2 in [1] needs a modification, a fact is known to Grojnowski and Tanisaki long time ago.In this paper we also show an interesting relation between Hq and an Hecke algebra corresponding to a certain Coxeter group.Apparently the idea in this paper works for all affine Weyl groups, but that is the theme of another paper.

  8. Neuroprotective effects of high affinity Σ1 receptor selective compounds.

    Science.gov (United States)

    Luedtke, Robert R; Perez, Evelyn; Yang, Shao-Hua; Liu, Ran; Vangveravong, Suwanna; Tu, Zhude; Mach, Robert H; Simpkins, James W

    2012-03-02

    We previously reported that the antipsychotic drug haloperidol, a multifunctional D2-like dopamine and sigma receptor subtype antagonist, has neuroprotective properties. In this study we further examined the association between neuroprotection and receptor antagonism by evaluating a panel of novel compounds with varying affinity at sigma and D2-like dopamine receptors. These compounds were evaluated using an in vitro cytotoxicity assay that utilizes a hippocampal-derived cell line, HT-22, in the presence or absence of varying concentrations (5 to 20 mM) of glutamate. While haloperidol was found to be a potent neuroprotective agent in this in vitro cell assay, the prototypic sigma 1 receptor agonist (+)-pentazocine was found not to be neuroprotective. Subsequently, the potency for the neuroprotection of HT-22 cells was evaluated for a) three SV series indoles which have nMolar affinity at D2-like receptors but varying affinity at sigma 1 receptor and b) two benzyl phenylacetamides sigma 1 receptor selective compounds which bind with low affinity at D2-like receptors but have nMolar affinity for the sigma 1 receptor. We observed that cytoprotection correlated with the affinity of the compounds for sigma 1 receptors. Based upon results from the HT-22 cell-based in vitro assay, two phenylacetamides, LS-127 and LS-137, were further evaluated in vivo using a transient middle cerebral artery occlusion (t-MCAO) model of stroke. At a dose of 100 μg/kg, both LS-127 and LS-137 attenuated infarct volume by approximately 50%. These studies provide further evidence that sigma 1 receptor selective compounds can provide neuroprotection in cytotoxic situations. These results also demonstrate that sigma 1 receptor selective benzyl phenylacetamides are candidate pharmacotherapeutic agents that could be used to minimize neuronal death after a stroke or head trauma.

  9. A multiobjective evolutionary algorithm to find community structures based on affinity propagation

    Science.gov (United States)

    Shang, Ronghua; Luo, Shuang; Zhang, Weitong; Stolkin, Rustam; Jiao, Licheng

    2016-07-01

    Community detection plays an important role in reflecting and understanding the topological structure of complex networks, and can be used to help mine the potential information in networks. This paper presents a Multiobjective Evolutionary Algorithm based on Affinity Propagation (APMOEA) which improves the accuracy of community detection. Firstly, APMOEA takes the method of affinity propagation (AP) to initially divide the network. To accelerate its convergence, the multiobjective evolutionary algorithm selects nondominated solutions from the preliminary partitioning results as its initial population. Secondly, the multiobjective evolutionary algorithm finds solutions approximating the true Pareto optimal front through constantly selecting nondominated solutions from the population after crossover and mutation in iterations, which overcomes the tendency of data clustering methods to fall into local optima. Finally, APMOEA uses an elitist strategy, called "external archive", to prevent degeneration during the process of searching using the multiobjective evolutionary algorithm. According to this strategy, the preliminary partitioning results obtained by AP will be archived and participate in the final selection of Pareto-optimal solutions. Experiments on benchmark test data, including both computer-generated networks and eight real-world networks, show that the proposed algorithm achieves more accurate results and has faster convergence speed compared with seven other state-of-art algorithms.

  10. Strength through unity: spatial affinity between morphs improves fitness in incompatible heterostylous Melochia (Malvaceae) species.

    Science.gov (United States)

    Faife-Cabrera, Michel; Navarro, Luis; Ferrero, Victoria

    2015-01-01

    In heterostylous plants, both stylar polymorphism and incompatibility system favor legitimate pollination among individuals. Weak or partial expression of incompatibility may ensure progeny when mates or pollinators are scarce in unstable habitats, but under these conditions plants with heteromorphic incompatibility would be in disadvantage. In this work we determine how the spatial distribution of morphs and the effect of proximity to the nearest potential mates affect plants' reproductive output in four Melochia species. The general prediction of decreasing reproductive success with an increasing isolation of floral morphs in plants with heteromorphic incompatibility was corroborated only in one species (i.e. M. tomentosa). Meanwhile, the other species exhibit a spatial affinity between morphs (i.e. the number of individuals with the nearest neighbor of the opposite morph exceeds expectations upon a random distribution). For M. savannarum and M. villosa we could not detect any effect of proximity to potential mates on the seed-ovule ratio. This may be due to: (1) existence of pollinators with long flying distances, like butterflies, in the populations and/or, (2) the possible occurrence of resource limitation. Spatial affinity between morphs in populations of heterostylous plants with heteromorphic incompatibility system increases reproductive success and may facilitate colonization of ephemeral habitats.

  11. Ancient DNA from European early neolithic farmers reveals their near eastern affinities.

    Directory of Open Access Journals (Sweden)

    Wolfgang Haak

    Full Text Available In Europe, the Neolithic transition (8,000-4,000 B.C. from hunting and gathering to agricultural communities was one of the most important demographic events since the initial peopling of Europe by anatomically modern humans in the Upper Paleolithic (40,000 B.C.. However, the nature and speed of this transition is a matter of continuing scientific debate in archaeology, anthropology, and human population genetics. To date, inferences about the genetic make up of past populations have mostly been drawn from studies of modern-day Eurasian populations, but increasingly ancient DNA studies offer a direct view of the genetic past. We genetically characterized a population of the earliest farming culture in Central Europe, the Linear Pottery Culture (LBK; 5,500-4,900 calibrated B.C. and used comprehensive phylogeographic and population genetic analyses to locate its origins within the broader Eurasian region, and to trace potential dispersal routes into Europe. We cloned and sequenced the mitochondrial hypervariable segment I and designed two powerful SNP multiplex PCR systems to generate new mitochondrial and Y-chromosomal data from 21 individuals from a complete LBK graveyard at Derenburg Meerenstieg II in Germany. These results considerably extend the available genetic dataset for the LBK (n = 42 and permit the first detailed genetic analysis of the earliest Neolithic culture in Central Europe (5,500-4,900 calibrated B.C.. We characterized the Neolithic mitochondrial DNA sequence diversity and geographical affinities of the early farmers using a large database of extant Western Eurasian populations (n = 23,394 and a wide range of population genetic analyses including shared haplotype analyses, principal component analyses, multidimensional scaling, geographic mapping of genetic distances, and Bayesian Serial Simcoal analyses. The results reveal that the LBK population shared an affinity with the modern-day Near East and Anatolia, supporting

  12. The growth rate of symplectic homology and affine varieties

    CERN Document Server

    McLean, Mark

    2010-01-01

    We will show that the cotangent bundle of an integrally hyperbolic manifold is not symplectomorphic to any smooth affine variety. We will also show that the unit cotangent bundle of such a manifold is not Stein fillable by a Stein domain whose completion is symplectomorphic to a smooth affine variety. For instance, these results hold when our manifolds are simply connected with at least one Betti number greater than the corresponding Betti number of the n torus. We use an invariant called the growth rate of symplectic homology to prove this result.

  13. Affine group representation formalism for four dimensional, Lorentzian, quantum gravity

    CERN Document Server

    Ching-Yi, Chou; Soo, Chopin

    2012-01-01

    The Hamiltonian constraint of 4-dimensional General Relativity is recast explicitly in terms of the Chern--Simons functional and the local volume operator. In conjunction with the algebraic quantization program, application of the affine quantization concept due to Klauder facilitates the construction of solutions to all of the the quantum constraints in the Ashtekar variables and their associated Hilbert space. A physical Hilbert space is constructed for Lorentzian signature gravity with nonzero cosmological constant in the form of unitary, irreducible representations of the affine group.

  14. Affine transformation crossed product like algebras and noncommutative surfaces

    CERN Document Server

    Arnlind, Joakim

    2009-01-01

    Several classes of *-algebras associated to the action of an affine transformation are considered, and an investigation of the interplay between the different classes of algebras is initiated. Connections are established that relate representations of *-algebras, geometry of algebraic surfaces, dynamics of affine transformations, graphs and algebras coming from a quantization procedure of Poisson structures. In particular, algebras related to surfaces being inverse images of fourth order polynomials (in R^3) are studied in detail, and a close link between representation theory and geometric properties is established for compact as well as non-compact surfaces.

  15. Solid support resins and affinity purification mass spectrometry.

    Science.gov (United States)

    Havis, Spencer; Moree, Wilna J; Mali, Sujina; Bark, Steven J

    2017-02-28

    Co-affinity purification-mass spectrometry (CoAP-MS) is a primary technology for elucidating the protein-protein interactions that form the basis of all biological processes. A critical component of CoAP-MS is the affinity purification (AP) of the bait protein, usually by immobilization of an antibody to a solid-phase resin. This Minireview discusses common resins, reagents, tagging methods, and their consideration for successful AP of tagged proteins. We discuss our experiences with different solid supports, their impact in AP experiments, and propose areas where chemistry can advance this important technology.

  16. Affinity Labeling of Membrane Receptors Using Tissue-Penetrating Radiations

    Science.gov (United States)

    Wong, Franklin C.; Boja, John; Ho, Beng; Kuhar, Michael J.; Wong, Dean F.

    2013-01-01

    Photoaffinity labeling, a useful in vivo biochemical tool, is limited when applied in vivo because of the poor tissue penetration by ultraviolet (UV) photons. This study investigates affinity labeling using tissue-penetrating radiation to overcome the tissue attenuation and irreversibly label membrane receptor proteins. Using X-ray (115 kVp) at low doses (affinity labeling of membrane receptors in a manner similar to UV with photoreactive ligands of the dopamine transporter, D2 dopamine receptor (D2R), and peripheral benzodiazepine receptor (PBDZR). It may provide specific noninvasive irreversible block or stimulation of a receptor using tissue-penetrating radiation targeting selected anatomic sites. PMID:23936811

  17. Affine diffusions and related processes simulation, theory and applications

    CERN Document Server

    Alfonsi, Aurélien

    2015-01-01

    This book gives an overview of affine diffusions, from Ornstein-Uhlenbeck processes to Wishart processes and it considers some related diffusions such as Wright-Fisher processes. It focuses on different simulation schemes for these processes, especially second-order schemes for the weak error. It also presents some models, mostly in the field of finance, where these methods are relevant and provides some numerical experiments. The book explains the mathematical background to understand affine diffusions and analyze the accuracy of the schemes.  

  18. Ferromagnetic Levan Composite: An Affinity Matrix to Purify Lectin

    Directory of Open Access Journals (Sweden)

    Renata Angeli

    2009-01-01

    Full Text Available A simple and inexpensive procedure used magnetite and levan to synthesize a composite recovered by a magnetic field. Lectins from Canavalia ensiformis (Con A and Cratylia mollis (Cramoll 1 and Cramoll 1,4 did bind specifically to composite. The magnetic property of derivative favored washing out contaminating proteins and recovery of pure lectins with glucose elution. Cramoll 1 was purified by this affinity binding procedure in two steps instead of a previous three-step protocol with ammonium sulfate fractionation, affinity chromatography on Sephadex G-75, and ion exchange chromatography through a CM-cellulose column.

  19. Whole transcriptome analysis for T cell receptor-affinity and IRF4-regulated clonal expansion of T cells

    Directory of Open Access Journals (Sweden)

    Wei Shi

    2014-12-01

    Full Text Available Clonal population expansion of T cells during an immune response is dependent on the affinity of the T cell receptor (TCR for its antigen [1]. However, there is little understanding of how this process is controlled transcriptionally. We found that the transcription factor IRF4 was induced in a manner dependent on TCR-affinity and was critical for the clonal expansion and maintenance of effector function of antigen-specific CD8+ T cells. We performed a genome-wide expression profiling experiment using RNA sequencing technology (RNA-seq to interrogate global expression changes when IRF4 was deleted in CD8+ T cells activated with either a low or high affinity peptide ligand. This allowed us not only to determine IRF4-dependent transcriptional changes but also to identify transcripts dependent on TCR-affinity [2]. Here we describe in detail the analyses of the RNA-seq data, including quality control, read mapping, quantification, normalization and assessment of differential gene expression. The RNA-seq data can be accessed from Gene Expression Omnibus database (accession number GSE49929.

  20. Preferential affinity of /sup 3/H-2-oxo-quazepam for type I benzodiazepine recognition sites in the human brain

    Energy Technology Data Exchange (ETDEWEB)

    Corda, M.G.; Giorgi, O.; Longoni, B.; Ongini, E.; Montaldo, S.; Biggio, G.

    1988-01-01

    The hypnotic drug quazepam and its active metabolite 2-oxo-quazepam (2-oxo-quaz) are two benzodiazepines (BZ) containing a trifluoroethyl moiety on the ring nitrogen at position 1, characterized by their preferential affinity for Type I BZ recognition sites. In the present study we characterized the binding of /sup 3/H-2-oxo-quaz in discrete areas of the human brain. Saturation analysis demonstrated specific and saturable binding of /sup 3/H-2-oxo-quaz to membrane preparations from human cerebellum. Hill plot analysis of displacement curves of /sup 3/H-flunitrazepam binding by 2-oxo-quaz yielded Hill coefficients of approximately 1 in the cerebellum and significantly less than 1 in the cerebral cortex, hippocampus, caudate nucleus, thalamus and pons. Self and cross displacement curves for /sup 3/H-FNT and /sup 3/H-2-oxo-quaz binding in these brain areas indicated that 2-oxo-quaz binds with different affinities to two populations of binding sites. High affinity binding sites were more abundant in the cerebellum, cerebral cortex, hippocampus and thalamus, whereas low affinity sites were predominant in the caudate nucleus and pons. Competition studies of /sup 3/H-2-oxo-quaz and /sup 3/H-FNT using unlabelled ligands indicated that compounds which preferentially bind to Type I sites are more potent at displacing /sup 3/H-2-oxo-quaz than /sup 3/H-FNT from cerebral cortex membrane preparations. 26 references, 2 figures, 3 tables.

  1. Origens do pensamento radical na América Latina: um estudo comparativo entre José Martí, Juan B. Justo e Ricardo Flores Magón

    Directory of Open Access Journals (Sweden)

    Fabio Luis Barbosa dos Santos

    2015-01-01

    Full Text Available Resumo Este artigo condensa os resultados, no plano ideológico, de uma pesquisa que analisa, em uma perspectiva comparada, como nascem, evoluem e são frustrados três projetos de democratização radical na América Latina nos primórdios do Imperialismo. José Martí (1853-1895 em Cuba, Juan B. Justo (1865-1928 na Argentina e Ricardo Flores Magón (1874-1922 no México lideraram esforços intelectuais e políticos visando superar os constrangimentos à integração nacional legados pela origem colonial, expressando-se em um pensamento que fundamentou a atuação dos partidos por eles dirigidos. Nossa hipótese é que esses autores, partindo de premissas ideológicas e políticas distintas mas orientados por um desígnio democrático comum, sugeriram balizas que referenciavam a máxima consciência possível da militância radical no continente, naquele contexto.

  2. The "Black Portuguese" on Pulau Flores and its Neighboring Islands%印尼弗洛勒斯及其附近岛屿上的"黑色葡萄牙人"

    Institute of Scientific and Technical Information of China (English)

    何平

    2006-01-01

    @@ 在印度尼西亚的弗洛勒斯岛(Pulau Flores)上,有一个族群特别引人注目,他们的皮肤是黑色的,面孔却又是欧洲人的样子,信奉的宗教也是天主教.在当地,许多人把他们称为"黑色葡萄牙人",说明他们是由葡萄牙人与当地民族混血而形成的一个新族群.但是,这个族群是什么时候以及怎样形成的?他们在当地发展、演变的历史如何?许多人并不十分清楚.因此,笔者根据所掌握的资料,对这个族群的由来以及他们的历史变迁做一个简要的论述.

  3. Comercialização de flores e plantas ornamentais no segmento varejista no município de Lavras/MG Flowes and ornamentals plantas commercialization in retailer segment at Lavras/MG

    Directory of Open Access Journals (Sweden)

    Marina Ceratti

    2007-08-01

    Full Text Available O mercado brasileiro de flores e plantas ornamentais apresenta-se com perspectivas de crescimento e conseqüente incremento para os principais segmentos da cadeia produtiva: produção, distribuição e comercialização. Esta previsão, bastante otimista, vem atraindo para o setor novos empreendedores, com conseqüente aumento da concorrência e a constante necessidade da busca por novos produtos e serviços. Com o objetivo de compreender a nova tendência da cadeia de flores e plantas ornamentais e de avaliar a estrutura do segmento varejista no município de Lavras (MG, realizou-se um levantamento de informações junto aos estabelecimentos que comercializam flores e plantas ornamentais, no primeiro semestre de 2003. Para tanto, utilizou-se de uma pesquisa de caráter exploratório, com perguntas voltadas à estrutura operacional da empresa, além de questões sociais sobre o florista, podendo-se citar o nível de conhecimento na área e preocupação com atualização. No município não há estabelecimentos com auto-serviço de flores e plantas ornamentais, apenas floriculturas comerciais, que totalizam 11 estabelecimentos, dentre os quais, 64% realizam projetos paisagísticos, 73% oferecem trabalhos de jardinagem, e 45% possuem produção própria, sendo que esta se caracteriza, de modo geral, por plantios protegidos em pequenas áreas, voltados para o próprio abastecimento, apenas com cultivos orgânicos, simplificados, de mudas para jardim. Assim, todos dependem do fornecimento regular de plantas, em sua maioria realizado diretamente por grandes atacadistas, ponto a ponto. De maneira geral, observou-se que os varejistas limitam-se à participação na disputa de preços, mostrando-se preocupados com os altos níveis de competitividade em que o mercado encontra-se e menos interessados na diversificação dos produtos e serviços e estratégias de marketing. Por outro lado, há poucos comerciantes voltados para a oferta de produtos com

  4. Prediction of peptide bonding affinity: kernel methods for nonlinear modeling

    CERN Document Server

    Bergeron, Charles; Sundling, C Matthew; Krein, Michael; Katt, Bill; Sukumar, Nagamani; Breneman, Curt M; Bennett, Kristin P

    2011-01-01

    This paper presents regression models obtained from a process of blind prediction of peptide binding affinity from provided descriptors for several distinct datasets as part of the 2006 Comparative Evaluation of Prediction Algorithms (COEPRA) contest. This paper finds that kernel partial least squares, a nonlinear partial least squares (PLS) algorithm, outperforms PLS, and that the incorporation of transferable atom equivalent features improves predictive capability.

  5. Self-affine roughness influence on the Casimir effect

    NARCIS (Netherlands)

    Palasantzas, G

    2005-01-01

    In this work we investigate the influence of self-affine roughness on the Casimir energy for plate-plate geometry. The plate roughness is characterized by the rms roughness amplitude w, the lateral correlation length xi, and the roughness exponent H. It is shown that the latter has a prominent effec

  6. An axially symmetric solution of metric-affine gravity

    CERN Document Server

    Vlachynsky, E J; Obukhov, Yu N; Hehl, F W

    1996-01-01

    We present an exact stationary {\\it axially symmetric} vacuum solution of metric-affine gravity (MAG) which generalises the recently reported spherically symmetric solution. Besides the metric, it carries nonmetricity and torsion as post-Riemannian geometrical structures. The parameters of the solution are interpreted as mass and angular momentum and as dilation, shear and spin charges.

  7. Smooth surfaces from bilinear patches: Discrete affine minimal surfaces

    KAUST Repository

    Käferböck, Florian

    2013-06-01

    Motivated by applications in freeform architecture, we study surfaces which are composed of smoothly joined bilinear patches. These surfaces turn out to be discrete versions of negatively curved affine minimal surfaces and share many properties with their classical smooth counterparts. We present computational design approaches and study special cases which should be interesting for the architectural application. 2013 Elsevier B.V.

  8. Affinity purification of polysaccharide degrading enzymes with crosslinked substrates

    NARCIS (Netherlands)

    Rozie, H.J.

    1992-01-01

    The aim of this work was to find economically favourable, affinity based, purification methods for several polysaccharide splitting bulk enzymes. The framework in which this study is done is described in Chapter 1.

    Chapter 2 describes the adsorption of endo-polygalacturonase (endoPG

  9. Combinatorial Vector Fields for Piecewise Affine Control Systems

    DEFF Research Database (Denmark)

    Wisniewski, Rafal; Larsen, Jesper Abildgaard

    2008-01-01

    This paper is intended to be a continuation of Habets and van Schuppen (2004) and Habets, Collins and van Schuppen (2006), which address the control problem for piecewise-affine systems on an arbitrary polytope or a family of these. Our work deals with the underlying combinatorics of the underlyi...

  10. Lie algebras and degenerate Affine Hecke Algebras of type A

    CERN Document Server

    Arakawa, T

    1997-01-01

    We construct a family of exact functors from the BGG category of representations of the Lie algebra sl to the category of finite-dimensional representations of the degenerate (or graded) affine Hecke algebra H of GL. These functors transform Verma modules to standard modules or zero, and simple modules to simple modules or zero. Any simple H-module can be thus obtained.

  11. Affinity purification of polysaccharide degrading enzymes with crosslinked substrates

    NARCIS (Netherlands)

    Rozie, H.J.

    1992-01-01

    The aim of this work was to find economically favourable, affinity based, purification methods for several polysaccharide splitting bulk enzymes. The framework in which this study is done is described in Chapter 1.

    Chapter 2 describes the adsorption of endo-polygalacturonase

  12. Self-Affine Sets with Positive Lebesgue Measure

    NARCIS (Netherlands)

    Dajani, Karma; Jiang, Kan; Kempton, Tom

    2014-01-01

    Using techniques introduced by C. G ̈unt ̈urk, we prove that the attractors of a family of overlapping self-affine iterated function systems contain a neighbourhood of zero for all parameters in a certain range. This corresponds to giving conditions under which a single sequence may serve as a ‘simu

  13. T-Duality in Affine NA Toda Models

    CERN Document Server

    Gomes, J F; Zimerman, A H

    2004-01-01

    The construction of Non Abelian affine Toda models is discussed in terms of its underlying Lie algebraic structure. It is shown that a subclass of such non conformal two dimensional integrable models naturally leads to the construction of a pair of actions which share the same spectra and are related by canonical transformations.

  14. Algebraic and analytic Dirac induction for graded affine Hecke algebras

    NARCIS (Netherlands)

    Ciubotaru, D.; Opdam, E.M.; Trapa, P.E.

    2014-01-01

    We define the algebraic Dirac induction map IndD for graded affine Hecke algebras. The map IndD is a Hecke algebra analog of the explicit realization of the Baum-Connes assembly map in the K-theory of the reduced C∗-algebra of a real reductive group using Dirac operators. The definition of IndD is

  15. On global asymptotic controllability of planar affine nonlinear systems

    Institute of Scientific and Technical Information of China (English)

    SUN Yimin; GUO Lei

    2005-01-01

    In this paper, we present a necessary and sufficient condition for globally asymptotic controllability of the general planar affine nonlinear systems with single-input.This result is obtained by introducing a new method in the analysis, which is based on the use of some basic results in planar topology and in the geometric theory of ordinary differential equations.

  16. Reconfigurable Control of Input Affine Nonlinear Systems under Actuator Fault

    DEFF Research Database (Denmark)

    Tabatabaeipour, Mojtaba; Galeazzi, Roberto

    2015-01-01

    This paper proposes a fault tolerant control method for input-affine nonlinear systems using a nonlinear reconfiguration block (RB). The basic idea of the method is to insert the RB between the plant and the nominal controller such that fault tolerance is achieved without re-designing the nominal...

  17. Affine group formulation of the Standard Model coupled to gravity

    CERN Document Server

    Chou, Ching-Yi; Soo, Chopin

    2013-01-01

    Using the affine group formalism, we perform a nonperturbative quantization leading to the construction of elements of a physical Hilbert space for full, Lorentzian quantum gravity coupled to the Standard Model in four spacetime dimensions. This paper constitutes a first step toward understanding the phenomenology of quantum gravitational effects stemming from a consistent treatment of minimal couplings to matter.

  18. Poincare series of subsets of affine Weyl groups

    OpenAIRE

    Viswanath, Sankaran

    2006-01-01

    In this note, we identify a natural class of subsets of affine Weyl groups whose Poincare series are rational functions. This class includes the sets of minimal coset representatives of reflection subgroups. As an application, we construct a generalization of the classical length-descent generating function, and prove its rationality.

  19. Electrochemical affinity biosensors for detection of mycotoxins: A review.

    Science.gov (United States)

    Vidal, Juan C; Bonel, Laura; Ezquerra, Alba; Hernández, Susana; Bertolín, Juan R; Cubel, Carlota; Castillo, Juan R

    2013-11-15

    This review discusses the current state of electrochemical biosensors in the determination of mycotoxins in foods. Mycotoxins are highly toxic secondary metabolites produced by molds. The acute toxicity of these results in serious human and animal health problems, although it has been only since early 1960s when the first studied aflatoxins were found to be carcinogenic. Mycotoxins affect a broad range of agricultural products, most important cereals and cereal-based foods. A majority of countries, mentioning especially the European Union, have established preventive programs to control contamination and strict laws of the permitted levels in foods. Official methods of analysis of mycotoxins normally requires sophisticated instrumentation, e.g. liquid chromatography with fluorescence or mass detectors, combined with extraction procedures for sample preparation. For about sixteen years, the use of simpler and faster analytical procedures based on affinity biosensors has emerged in scientific literature as a very promising alternative, particularly electrochemical (i.e., amperometric, impedance, potentiometric or conductimetric) affinity biosensors due to their simplicity and sensitivity. Typically, electrochemical biosensors for mycotoxins use specific antibodies or aptamers as affinity ligands, although recombinant antibodies, artificial receptors and molecular imprinted polymers show potential utility. This article deals with recent advances in electrochemical affinity biosensors for mycotoxins and covers complete literature from the first reports about sixteen years ago.

  20. Efficient importance sampling in low dimensions using affine arithmetic

    OpenAIRE

    Everitt, Richard G.

    2017-01-01

    Despite the development of sophisticated techniques such as sequential Monte Carlo, importance sampling (IS) remains an important Monte Carlo method for low dimensional target distributions. This paper describes a new technique for constructing proposal distributions for IS, using affine arithmetic. This work builds on the Moore rejection sampler to which we provide a comparison.

  1. HAUSDORFF DIMENSION OF GENERALIZED STATISTICALLY SELF-AFFINE FRACTALS

    Institute of Scientific and Technical Information of China (English)

    余旌胡; 丁立新

    2004-01-01

    The authors consider generalized statistically self-affine recursive fractals K with random numbers of subsets on each level. They obtain the Hausdorff dimensions of K without considering whether the subsets on each level are non-overlapping or not. They also give some examples to show that many important sets are the special cases of their models.

  2. An Affine Invariant $k$-Nearest Neighbor Regression Estimate

    CERN Document Server

    Biau, Gérard; Dujmovic, Vida; Krzyzak, Adam

    2012-01-01

    We design a data-dependent metric in $\\mathbb R^d$ and use it to define the $k$-nearest neighbors of a given point. Our metric is invariant under all affine transformations. We show that, with this metric, the standard $k$-nearest neighbor regression estimate is asymptotically consistent under the usual conditions on $k$, and minimal requirements on the input data.

  3. Affinity membranes for hormone removal from aqueous solutions

    NARCIS (Netherlands)

    Urmenyi, A.M.; Poot, Andreas A.; Wessling, Matthias; Mulder, M.H.V.

    2005-01-01

    A novel affinity membrane was prepared by covalent binding of antibodies (against 17--estradiol) to a micro-porous poly(ethylene vinyl alcohol) (EVAL) membrane, taking benefit from the high surface area of EVAL membranes and the large number of reactive groups available for further surface

  4. Properties of an affine transport equation and its holonomy

    Science.gov (United States)

    Vines, Justin; Nichols, David A.

    2016-10-01

    An affine transport equation was used recently to study properties of angular momentum and gravitational-wave memory effects in general relativity. In this paper, we investigate local properties of this transport equation in greater detail. Associated with this transport equation is a map between the tangent spaces at two points on a curve. This map consists of a homogeneous (linear) part given by the parallel transport map along the curve plus an inhomogeneous part, which is related to the development of a curve in a manifold into an affine tangent space. For closed curves, the affine transport equation defines a "generalized holonomy" that takes the form of an affine map on the tangent space. We explore the local properties of this generalized holonomy by using covariant bitensor methods to compute the generalized holonomy around geodesic polygon loops. We focus on triangles and "parallelogramoids" with sides formed from geodesic segments. For small loops, we recover the well-known result for the leading-order linear holonomy (˜ Riemann × area), and we derive the leading-order inhomogeneous part of the generalized holonomy (˜ Riemann × area^{3/2}). Our bitensor methods let us naturally compute higher-order corrections to these leading results. These corrections reveal the form of the finite-size effects that enter into the holonomy for larger loops; they could also provide quantitative errors on the leading-order results for finite loops.

  5. Several Affinity Tags Commonly Used in Chromatographic Purification

    Directory of Open Access Journals (Sweden)

    Xinyu Zhao

    2013-01-01

    Full Text Available Affinity tags have become powerful tools from basic biological research to structural and functional proteomics. They were widely used to facilitate the purification and detection of proteins of interest, as well as the separation of protein complexes. Here, we mainly discuss the benefits and drawbacks of several affinity or epitope tags frequently used, including hexahistidine tag, FLAG tag, Strep II tag, streptavidin-binding peptide (SBP tag, calmodulin-binding peptide (CBP, glutathione S-transferase (GST, maltose-binding protein (MBP, S-tag, HA tag, and c-Myc tag. In some cases, a large-size affinity tag, such as GST or MBP, can significantly impact on the structure and biological activity of the fusion partner protein. So it is usually necessary to excise the tag by protease. The most commonly used endopeptidases are enterokinase, factor Xa, thrombin, tobacco etch virus, and human rhinovirus 3C protease. The proteolysis features of these proteases are described in order to provide a general guidance on the proteolytic removal of the affinity tags.

  6. "The Hunger Games": Literature, Literacy, and Online Affinity Spaces

    Science.gov (United States)

    Curwood, Jen Scott

    2013-01-01

    This article examines adolescent literacy practices related to "The Hunger Games," a young adult novel and the first of a trilogy. By focusing on the interaction of social identities, discourses, and media paratexts within an online affinity space, this ethnographic study offers insight into how young adults engage with contemporary…

  7. Affinity maturation of antibodies assisted by in silico modeling

    NARCIS (Netherlands)

    Barderas, R.; Desmet, J.; Timmerman, P.; Meloen, R.; Casal, J.I.

    2008-01-01

    Rational engineering methods can be applied with reasonable success to optimize physicochemical characteristics of proteins, in particular, antibodies. Here, we describe a combined CDR3 walking randomization and rational design-based approach to enhance the affinity of the human anti-gastrin TA4

  8. Demazure modules and vertex models the affine sl(2) case

    CERN Document Server

    Foda, O E; Okado, M; Foda, Omar; Misra, Kailash C; Okado, Masato

    1996-01-01

    We characterize, in the case of affine sl(2), the crystal base of the Demazure module E_w(\\La) in terms of extended Young diagrams or paths for any dominant integral weight \\La and Weyl group element w. Its character is evaluated via two expressions, 'bosonic' and 'fermionic'.

  9. Evaluation Codes from an Affine Veriety Code Perspective

    DEFF Research Database (Denmark)

    Geil, Hans Olav

    2008-01-01

    Evaluation codes (also called order domain codes) are traditionally introduced as generalized one-point geometric Goppa codes. In the present paper we will give a new point of view on evaluation codes by introducing them instead as particular nice examples of affine variety codes. Our study...

  10. Student Engagement and Neoliberalism: Mapping an Elective Affinity

    Science.gov (United States)

    Zepke, Nick

    2015-01-01

    The purpose of this article is to argue that student engagement, an important area for research about learning and teaching in formal higher education, has an elective affinity with neoliberalism, a hegemonic ideology in many countries of the developed world. The paper first surveys an extensive research literature examining student engagement and…

  11. Linear independence measure of logarithms over affine groups

    OpenAIRE

    Huicochea, Mario

    2015-01-01

    Linear forms in logarithms over connected commutative algebraic groups over the algebraic numbers field have been studied widely. However, the theory of linear forms in logarithms over noncommutative algebraic groups have not been developed as the one of the commutative algebraic groups and in this paper we start studying linear forms in logarithms over affine groups.

  12. Radiosynthesis and Evaluation of [(11)C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites.

    Science.gov (United States)

    Jensen, Claus H; Hansen, Hanne D; Bay, Tina; Vogensen, Stine B; Lehel, Szabolcs; Thiesen, Louise; Bundgaard, Christoffer; Clausen, Rasmus P; Knudsen, Gitte M; Herth, Matthias M; Wellendorph, Petrine; Frølund, Bente

    2017-01-18

    γ-Hydroxybutyric acid (GHB) is an endogenous neuroactive substance and proposed neurotransmitter with affinity for both low- and high-affinity binding sites. A radioligand with high and specific affinity toward the high-affinity GHB binding site would be a unique tool toward a more complete understanding of this population of binding sites. With its high specific affinity and monocarboxylate transporter (MCT1) mediated transport across the blood-brain barrier in pharmacological doses, 3-hydroxycyclopent-1-enecarboxylic acid (HOCPCA) seems like a suitable PET radiotracer candidate. Here, we report the (11)C-labeling and subsequent evaluation of [(11)C]HOCPCA in a domestic pig, as a PET-radioligand for visualization of the high-affinity GHB binding sites in the live pig brain. To investigate the regional binding of HOCPCA in pig brain prior to in vivo PET studies, in vitro quantitative autoradiography on sections of pig brain was performed using [(3)H]HOCPCA. In vivo evaluation of [(11)C]HOCPCA showed no brain uptake, possibly due to a limited uptake of HOCPCA by the MCT1 transporter at tracer doses of [(11)C]HOCPCA.

  13. Semiempirical Theories of the Affinities of Negative Atomic Ions

    Science.gov (United States)

    Edie, John W.

    1961-01-01

    The determination of the electron affinities of negative atomic ions by means of direct experimental investigation is limited. To supplement the meager experimental results, several semiempirical theories have been advanced. One commonly used technique involves extrapolating the electron affinities along the isoelectronic sequences, The most recent of these extrapolations Is studied by extending the method to Include one more member of the isoelectronic sequence, When the results show that this extension does not increase the accuracy of the calculations, several possible explanations for this situation are explored. A different approach to the problem is suggested by the regularities appearing in the electron affinities. Noting that the regular linear pattern that exists for the ionization potentials of the p electrons as a function of Z, repeats itself for different degrees of ionization q, the slopes and intercepts of these curves are extrapolated to the case of the negative Ion. The method is placed on a theoretical basis by calculating the Slater parameters as functions of q and n, the number of equivalent p-electrons. These functions are no more than quadratic in q and n. The electron affinities are calculated by extending the linear relations that exist for the neutral atoms and positive ions to the negative ions. The extrapolated. slopes are apparently correct, but the intercepts must be slightly altered to agree with experiment. For this purpose one or two experimental affinities (depending on the extrapolation method) are used in each of the two short periods. The two extrapolation methods used are: (A) an isoelectronic sequence extrapolation of the linear pattern as such; (B) the same extrapolation of a linearization of this pattern (configuration centers) combined with an extrapolation of the other terms of the ground configurations. The latter method Is preferable, since it requires only experimental point for each period. The results agree within

  14. Distance and affinity dependence of triplex-induced recombination.

    Science.gov (United States)

    Knauert, Melissa P; Lloyd, Janice A; Rogers, Faye A; Datta, Hirock J; Bennett, Michael L; Weeks, Daniel L; Glazer, Peter M

    2005-03-15

    Triplex-forming oligonucleotides (TFOs) have the potential to serve as gene therapeutic agents on the basis of their ability to mediate site-specific genome modification via induced recombination. However, high-affinity triplex formation is limited to polypurine/polypyrimidine sites in duplex DNA. Because of this sequence restriction, careful analysis is needed to identify suitable TFO target sites within or near genes of interest. We report here an examination of two key parameters which influence the efficiency of TFO-induced recombination: (1) binding affinity of the TFO for the target site and (2) the distance between the target site and the mutation to be corrected. To test the influence of binding affinity, we compared induced recombination in human cell-free extracts by a series of G-rich oligonucleotides with an identical base composition and an increasing number of mismatches in the third strand binding code. As the number of mismatches increased and, therefore, binding affinity decreased, induced recombination frequency also dropped. There was an apparent threshold at an equilibrium dissociation constant (K(d)) of 1 x 10(-)(7) M. In addition, TFO chemical modification with N,N-diethylethylenediamine (DEED) internucleoside linkages to confer improved binding was found to yield increased levels of induced recombination. To test the ability of triplex formation to induce recombination at a distance, episomal targets with informative reporter genes were constructed to contain polypurine TFO target sites at varying distances from the mutations to be corrected. TFO-induced recombination in mammalian cells between a plasmid vector and a donor oligonucleotide was detected at distances ranging from 24 to 750 bp. Together, these results indicate that TFO-induced recombination requires high-affinity binding but can affect sites hundreds of base pairs away from the position of triplex formation.

  15. PDZ affinity chromatography: a general method for affinity purification of proteins based on PDZ domains and their ligands.

    Science.gov (United States)

    Walkup, Ward G; Kennedy, Mary B

    2014-06-01

    PDZ (PSD-95, DiscsLarge, ZO1) domains function in nature as protein binding domains within scaffold and membrane-associated proteins. They comprise ∼90 residues and make specific, high affinity interactions with complementary C-terminal peptide sequences, with other PDZ domains, and with phospholipids. We hypothesized that the specific, strong interactions of PDZ domains with their ligands would make them well suited for use in affinity chromatography. Here we describe a novel affinity chromatography method applicable for the purification of proteins that contain PDZ domain-binding ligands, either naturally or introduced by genetic engineering. We created a series of affinity resins comprised of PDZ domains from the scaffold protein PSD-95, or from neuronal nitric oxide synthase (nNOS), coupled to solid supports. We used them to purify heterologously expressed neuronal proteins or protein domains containing endogenous PDZ domain ligands, eluting the proteins with free PDZ domain peptide ligands. We show that Proteins of Interest (POIs) lacking endogenous PDZ domain ligands can be engineered as fusion products containing C-terminal PDZ domain ligand peptides or internal, N- or C-terminal PDZ domains and then can be purified by the same method. Using this method, we recovered recombinant GFP fused to a PDZ domain ligand in active form as verified by fluorescence yield. Similarly, chloramphenicol acetyltransferase (CAT) and β-Galactosidase (LacZ) fused to a C-terminal PDZ domain ligand or an N-terminal PDZ domain were purified in active form as assessed by enzymatic assay. In general, PDZ domains and ligands derived from PSD-95 were superior to those from nNOS for this method. PDZ Domain Affinity Chromatography promises to be a versatile and effective method for purification of a wide variety of natural and recombinant proteins.

  16. Immunotherapy Expands and Maintains the Function of High-Affinity Tumor-Infiltrating CD8 T Cells In Situ.

    Science.gov (United States)

    Moran, Amy E; Polesso, Fanny; Weinberg, Andrew D

    2016-09-15

    Cancer cells harbor high-affinity tumor-associated Ags capable of eliciting potent antitumor T cell responses, yet detecting these polyclonal T cells is challenging. Therefore, surrogate markers of T cell activation such as CD69, CD44, and programmed death-1 (PD-1) have been used. We report in this study that in mice, expression of activation markers including PD-1 is insufficient in the tumor microenvironment to identify tumor Ag-specific T cells. Using the Nur77GFP T cell affinity reporter mouse, we highlight that PD-1 expression can be induced independent of TCR ligation within the tumor. Given this, we characterized the utility of the Nur77GFP model system in elucidating mechanisms of action of immunotherapies independent of PD-1 expression. Coexpression of Nur77GFP and OX40 identifies a polyclonal population of high-affinity tumor-associated Ag-specific CD8(+) T cells, which produce more IFN-γ in situ than OX40 negative and doubles in quantity with anti-OX40 and anti-CTLA4 mAb therapy but not with anti-PD-1 or programmed death ligand-1. Moreover, expansion of these high-affinity CD8 T cells prolongs survival of tumor-bearing animals. Upon chronic stimulation in tumors and after adoptive cell therapy, CD8 TCR signaling and Nur77GFP induction is impaired, and tumors progress. However, this can be reversed and overall survival significantly enhanced after adoptive cell therapy with agonist OX40 immunotherapy. Therefore, we propose that OX40 agonist immunotherapy can maintain functional TCR signaling of chronically stimulated tumor-resident CD8 T cells, thereby increasing the frequency of cytotoxic, high-affinity, tumor-associated Ag-specific cells.

  17. Cell-Type-Specific mRNA Purification by Translating Ribosome Affinity Purification (TRAP)

    Science.gov (United States)

    Heiman, Myriam; Kulicke, Ruth; Fenster, Robert J.; Greengard, Paul; Heintz, Nathaniel

    2014-01-01

    Cellular diversity and architectural complexity create barriers to understanding the function of the mammalian central nervous system (CNS) at a molecular level. To address this problem, we recently developed a methodology that provides the ability to profile the entire translated mRNA complement of any genetically defined cell population. This methodology, which we termed translating ribosome affinity purification, or TRAP, combines cell-type-specific transgene expression with affinity purification of translating ribosomes. TRAP can be used to study the cell-type-specific mRNA profiles of any genetically defined cell type, and has been successfully used to date in organisms ranging from D. melanogaster to mice and human cultured cells. Unlike other methodologies that rely upon micro-dissection, cell panning, or cell sorting, the TRAP methodology bypasses the need for tissue fixation or single-cell suspensions (and potential artifacts these treatments introduce), and reports on mRNAs in the entire cell body. This protocol provides a step-by-step guide to implementing the TRAP methodology, which takes two days to complete once all materials are in hand. PMID:24810037

  18. Algorithm-Architecture Affinity - Parallelism Changes the Picture

    DEFF Research Database (Denmark)

    Abildgren, Rasmus; Šaramentovas, Aleksandras; Ruzgys, Paulius;

    Reducing the time-to-market factor is a challenge for many embedded systems designers. In that respect, hardwaresoftware partitioning is a key issue which has been studied during the last two decades. In this paper we present an extension to recent works dealing with metrics for guiding...... the hardware-software partitioning step. This extension builds upon and complement our own work with metrics in the Design Trotter project, and is combined with the affinity metric approach. We show that the proposed extension improves the original affinity metric in terms of parallelism detection, and thus...... can help system designers to make wiser hardware-software partitioning decisions, which in turn reduces the time-to-market factor....

  19. Improved Energy-Momentum Currents in Metric-Affine Spacetime

    CERN Document Server

    Hecht, R D; McCrea, J D; Mielke, E W; Ne'eman, Yuval; Hecht, Ralf; Hehl, Friedrich W.; Mielke, Eckehard W.; Ne'eman, Yuval

    1992-01-01

    In Minkowski spacetime it is well-known that the canonical energy-momentum current is involved in the construction of the globally conserved currents of energy-momentum and total angular momentum. For the construction of conserved currents corresponding to (approximate) scale and proper conformal symmetries, however, an improved energy-momentum current is needed. By extending the Minkowskian framework to a genuine metric-affine spacetime, we find that the affine Noether identities and the conformal Killing equations enforce this improvement in a rather natural way. So far, no gravitational dynamics is involved in our construction. The resulting dilation and proper conformal currents are conserved provided the trace of the energy-momentum current satisfies a (mild) scaling relation or even vanishes.

  20. Reflection symmetry detection using locally affine invariant edge correspondence.

    Science.gov (United States)

    Wang, Zhaozhong; Tang, Zesheng; Zhang, Xiao

    2015-04-01

    Reflection symmetry detection receives increasing attentions in recent years. The state-of-the-art algorithms mainly use the matching of intensity-based features (such as the SIFT) within a single image to find symmetry axes. This paper proposes a novel approach by establishing the correspondence of locally affine invariant edge-based features, which are superior to the intensity based in the aspects that it is insensitive to illumination variations, and applicable to textureless objects. The locally affine invariance is achieved by simple linear algebra for efficient and robust computations, making the algorithm suitable for detections under object distortions like perspective projection. Commonly used edge detectors and a voting process are, respectively, used before and after the edge description and matching steps to form a complete reflection detection pipeline. Experiments are performed using synthetic and real-world images with both multiple and single reflection symmetry axis. The test results are compared with existing algorithms to validate the proposed method.