WorldWideScience

Sample records for fifty years 1876-1926

  1. Fifty years in neonatology.

    Science.gov (United States)

    Manley, Brett J; Doyle, Lex W; Davies, Mark W; Davis, Peter G

    2015-01-01

    Neonatology, the care and study of newborn infants, is a 'young' specialty. Over the last 50 years, there have been many advances in the way that neonatologists care for newborn infants, particularly those born preterm, leading to dramatic improvements in mortality. To illustrate these advances, we describe four eras in neonatology from the point of view of the junior hospital doctor.

  2. PAs: Fifty years young.

    Science.gov (United States)

    Mandel, Ellen D; North, Shannon

    2017-10-01

    The PA profession is 50 years young. Practicing PAs and current students hail from several generational categories ranging from Builders to Generation Z. This article reviews how different generations may have experienced PA program expansion, professional identity, state licensing, and prescription delegation. The authors sampled a cohort of PA program applicants about their views on what evokes optimism and concern for the PA profession. These themes mirror the recently paved professional road, while posing the all-important question: What construction lies on the horizon?

  3. Normalization Fifty Years Beyond

    DEFF Research Database (Denmark)

    Bonfils, Inge Storgaard; Tøssebro, Jan; Teittinen, Antti

    2012-01-01

    toward larger group homes and congregations, inequality across municipalities, marketization, and new public management, but also an increasing emphasis on consumer rights and the use of the personal assistance scheme in services for people with ID. The authors conclude that diverging trends coexist......, with improvements going together with significant setbacks. They explore the trends from a political science perspective and, in particular, note how they relate to recent shifts in public management and changing drivers of change....... test of the reforms is not what happens during reform years, but after the reform energy decreases and political attention fades. Thus, developments after 2000 are of particular interest. The comparative analysis is based on research reviews in the five Nordic countries. The analysis observed a trend...

  4. Lasers: The next fifty years

    NARCIS (Netherlands)

    Kärtner, Franz; Pollnau, Markus; Ueda, Ken-ichi; van Driel, Henry

    This year marks the 50th anniversary of the laser — the first coherent radiation source in the optical domain. This anniversary of this historic development is being celebrated this year through “Laserfest‿ in which the Optical Society is a major partner. The laser enabled a straightforward

  5. Fifty years of polymer science

    NARCIS (Netherlands)

    Prez, Du Filip; Hoogenboom, Richard; Klumperman, Bert; Meier, Michael; Monteiro, Michael; Müller, Alejandro; Vancso, Julius

    2015-01-01

    The European Polymer Journal (EPJ) has been serving the scientific community for 50 years, which makes it one of the older macromolecular journals with a broad focus. Since its launch 50 years ago, EPJ has provided a distinguished forum for publications in polymer research, including chemistry, phys

  6. Lasers: The next fifty years

    NARCIS (Netherlands)

    Kärtner, Franz; Pollnau, Markus; Ueda, Ken-ichi; Driel, van Henry

    2010-01-01

    This year marks the 50th anniversary of the laser — the first coherent radiation source in the optical domain. This anniversary of this historic development is being celebrated this year through “Laserfest” in which the Optical Society is a major partner. The laser enabled a straightforward extensio

  7. Vannevar Bush: Fifty Years Later

    Science.gov (United States)

    Lagowski, J. J.

    1995-12-01

    It is ironic that the 50th anniversary year of Vannevar Bush's Report to President Truman entitled "Science the Endless Frontier", which put into motion the eminently successful current system of education of scientists in this country occurs at a time when serious questions are being asked about the usefulness of that very system. Bush viewed his proposal to establish a national research foundation (later to be called the National Science Foundation) as a "social compact." Judgment of scientific merit would be delegated to expert peers in return for scientific progress, which would ultimately benefit the nation in terms of scientific needs--military security, economic productivity, and enhanced quality of life. Bush wanted the funding of basic research intertwined with training, and preferred to use universities for this purpose rather than industrial or national labs. Bush viewed college and university scientists as teachers and investigators. He believed university-based research would uniquely encourage and engage the next generation of scientists as no other institutional arrangement could. Bush did not trust industry's commitment to basic research, an instinct that proved prophetic. The academic reserve of scientists (PhD's in training and postdoctoral students) that existed before World War II, and upon which the United States could draw for its needs, which were primarily associated with defense efforts, was probably one of the defining factors in Bush's suggested strategy. Currently, that reserve of talent has gotten so large that it is the obvious throttle in the pipeline slowing the continued development of the university research enterprise. Since 1977, the rate at which we have trained new scientists exceeds an average of 4% annually. Since 1987, the "science work force"--PhD's--has grown at three times the rate of the general labor supply. Temporary positions for postdoctoral scientists have grown even faster (over 5% per year since 1989). To compound

  8. Fifty years of shear zones

    Science.gov (United States)

    Graham, Rodney

    2017-04-01

    We are here, of course, because 1967 saw the publication of John Ramsay's famous book. Two years later a memorable field trip from Imperial College to the Outer Hebrides saw John on a bleak headland on the coast of North Uist where a relatively undeformed metadolerite within Lewisian (Precambrian) gneisses contained ductile shear zones with metamorphic fabrics in amphibolite facies. One particular outcrop was very special - a shear zone cutting otherwise completely isotropic, undeformed metadolerite, with an incremental foliation starting to develop at 45° to the deformation zone, and increasing in intensity as it approached the shear direction. Here was proof of the process of simple shear under ductile metamorphic conditions - the principles of simple shear outlined in John Ramsay's 1967 book clearly visible in nature, and verified by Ramsay's mathematical proofs in the eventual paper (Ramsay and Graham, 1970). Later work on the Lewisian on the mainland of Scotland, in South Harris, in Africa, and elsewhere applied Ramsay's simple shear principles more liberally, more imprecisely and on larger scale than at Caisteal Odair, but in retrospect it documented what seems now to be the generality of mid and lower crustal deformation. Deep seismic reflection data show us that on passive margins hyper-stretched continental crust (whether or not cloaked by Seaward Dipping Reflectors) seems to have collapsed onto the mantle. Crustal faults mostly sole out at or above the mantle - so the Moho is a detachment- an 'outer marginal detachment', if you like, and, of course, it must be a ductile shear. On non-volcanic margins this shear zone forms the first formed ocean floor before true sea floor spreading gets going to create real oceanic crust. Gianreto Manatschal, Marcel Lemoine and others realised that the serpentinites described in parts of the Alps are exposed remnants of this ductile shear zone. Associated ophicalcite breccias tell of sea floor exposure, while high

  9. Information Systems Curricula: A Fifty Year Journey

    Science.gov (United States)

    Longenecker, Herbert E., Jr.; Feinstein, David; Clark, Jon D.

    2013-01-01

    This article presents the results of research to explore the nature of changes in skills over a fifty year period spanning the life of Information Systems model curricula. Work begun in 1999 was expanded both backwards in time, as well as forwards to 2012 to define skills relevant to Information Systems curricula. The work in 1999 was based on job…

  10. Human space exploration the next fifty years.

    Science.gov (United States)

    Williams, David R; Turnock, Matthew

    2011-06-01

    Preparation for the fiftieth anniversary of human spaceflight in the spring of 2011 provides the space faring nations with an opportunity to reflect on past achievements as well as consider the next fifty years of human spaceflight. The International Space Station is a unique platform for long duration life science research that will play a critical role in preparing for future human space exploration beyond low earth orbit. Some feel the future path back to the Moon and on to Mars may be delayed with the current commitment of the United States to support the development of human-rated commercial spacecraft. Others see this as a unique opportunity to leverage the capability of the private sector in expanding access to space exploration. This article provides an overview of the past achievements in human spaceflight and discusses future missions over the next fifty years and the role space medicine will play in extending the time-distance constant of human space exploration.

  11. Essay: fifty years of condensed matter physics.

    Science.gov (United States)

    Cohen, Marvin L

    2008-12-19

    Since the birth of Physical Review Letters fifty years ago, condensed matter physics has seen considerable growth, and both the journal and the field have flourished during this period. In this essay, I begin with some general comments about condensed matter physics and then give some personal views on the conceptual development of the field and list some highlights. The focus is mostly on theoretical developments.

  12. First Fifty Years of Chemoresistive Gas Sensors

    Directory of Open Access Journals (Sweden)

    Giovanni Neri

    2015-01-01

    Full Text Available The first fifty years of chemoresistive sensors for gas detection are here reviewed, focusing on the main scientific and technological innovations that have occurred in the field over the course of these years. A look at advances made in fundamental and applied research and leading to the development of actual high performance chemoresistive devices is presented. The approaches devoted to the synthesis of novel semiconducting materials with unprecedented nanostructure and gas-sensing properties have been also presented. Perspectives on new technologies and future applications of chemoresistive gas sensors have also been highlighted.

  13. Fifty Years After, Hidden Children Speak

    Directory of Open Access Journals (Sweden)

    Léa Marcou

    2008-06-01

    Full Text Available “For fifty years, I have not spoken of my childhood years in France during the second world war. A hidden child, I lived under a false name amongst unknown people, being careful – as I had been taught – not to reveal, by a gesture or by a word, that I was Jewish. I knew I was in danger, still not understanding why and I was constantly afraid. I didn't know whether I would see again one day my parents from whom I had been suddenly taken away. Nonetheless what were my pains compared to those of...

  14. Psychotherapists and the clergy: Fifty years later.

    Science.gov (United States)

    Spiegelman, J M

    1984-03-01

    Jung's two powerful articles on psychotherapy and the clergy, written in 1928 and 1932. are looked at from the vantage point of fifty years later and the author's experience in conducting analysis with many people from both vocations. He notes that relatively few people achieve the kind of integration of the ego that Jung writes about-an essentially religious experience-wherein the center of their existence now gravitates about the Self. Yet Jung's work and views have had a profound effect on spiritually inclined people of all ages. The predictions of Jung's articles, regarding therapy, the dissemination of pyschology to the masses, and other issues are examined.

  15. Cryogenic engineering fifty years of progress

    CERN Document Server

    Reed, Richard

    2007-01-01

    Cryogenic Engineering: Fifty Years of Progress is a benchmark reference work which chronicles the major developments in the field. Starting with an historical background dating to the 1850s, this book reviews the development of data resources now available for cryogenic fields and properties of materials. The advances in cryogenic fundamentals are covered by reviews of cryogenic principles, cryogenic insulation, low-loss storage systems, modern liquefaction processes, helium cryogenics and low-temperature thermometry. Several well-established applications resulting from cryogenic advances include aerospace cryocoolers and refrigerators, use of LTS and HTS systems in electrical applications, and recent changes in cryopreservation. Extensive references are provided for the readers interested in the details of these cryogenic engineering advances.

  16. [Fifty years of clinical use of warfarin].

    Science.gov (United States)

    Quintero-González, Jesús Alberto

    2010-06-01

    Warfarin is the most utilized oral anticoagulant for the long term prophylaxes of thrombosis. Its use has been increased as new clinical conditions, capable of leading to thrombosis, have been detected. Due to the special characteristics of warfarin, such as the variability of doses for each individual, the narrow margin between adequate and inadequate doses, interaction with multiple pharmaceutical products, interference of its action by vitamin K present in the diet and the possibility of hemorrhagic complications or thrombotic recurrence, this drug requires a very careful dosage and strict laboratory and clinical monitoring. Despite being in the market for more than de fifty years and its many disadvantages, warfarin has not been substituted for the new oral anticoagulants. In 1999, warfarin was positioned eleventh on the list of the most used medicines in the world.

  17. Fifty years of science, memories, and events

    CERN Multimedia

    2004-01-01

    In 2004 CERN celebrates its 50th anniversary. More precisely, on Wednesday 29 September 2004, the signature of the convention that established CERN will be 50 years old. During this special year, CERN's public web site will host a celebratory Fiftieth Anniversary web site.

  18. The Road Was Fifty Years Long

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    TIBET has always been a place of worldconcern. After the Democratic Reformin 1959, Tibet turned into a socialist societyfrom the former feudal serf system, whichwas an unprecedented historical step. Forforty years since then, the peace anddevelopment of Tibet have received specialattention and concern from the centralgovernment. Du Qiyuan, the president ofTibet Women’s Federation who grew up andhas worked in Tibet for years told me about

  19. Fifty years of allergy: 1965-2015.

    Science.gov (United States)

    Campbell, Dianne E; Mehr, Sam

    2015-01-01

    The last 50 years in allergy could almost be considered the first 50 years. Over this time period, we have witnessed the emergence of allergy as a subspecialty, have seen and continue to observe a tremendous change in prevalence of allergic disease and have gained insight into the mechanisms that underlie allergic predisposition and disease manifestation. We have improved the care of children with many forms of allergic disease and now sit poised to be able to alter the natural history of allergic disease with the use of specific immunotherapy. There is much left to do in the next 50 years including understanding what underlies both the predisposition to atopic disease and its natural resolution and identifying the environmental cofactors involved in the 'allergic epidemic' and therefore targets for effective primary prevention.

  20. Fifty Years of Innovation in Plastic Surgery

    Directory of Open Access Journals (Sweden)

    Richard M Kwasnicki

    2016-03-01

    Full Text Available BackgroundInnovation has molded the current landscape of plastic surgery. However, documentation of this process only exists scattered throughout the literature as individual articles. The few attempts made to profile innovation in plastic surgery have been narrative, and therefore qualitative and inherently biased. Through the implementation of a novel innovation metric, this work aims to identify and characterise the most prevalent innovations in plastic surgery over the last 50 years.MethodsPatents and publications related to plastic surgery (1960 to 2010 were retrieved from patent and MEDLINE databases, respectively. The most active patent codes were identified and grouped into technology areas, which were subsequently plotted graphically against publication data. Expert-derived technologies outside of the top performing patents areas were additionally explored.ResultsBetween 1960 and 2010, 4,651 patents and 43,118 publications related to plastic surgery were identified. The most active patent codes were grouped under reconstructive prostheses, implants, instruments, non-invasive techniques, and tissue engineering. Of these areas and other expert-derived technologies, those currently undergoing growth include surgical instruments, implants, non-invasive practices, transplantation and breast surgery. Innovations related to microvascular surgery, liposuction, tissue engineering, lasers and prostheses have all plateaued.ConclusionsThe application of a novel metric for evaluating innovation quantitatively outlines the natural history of technologies fundamental to the evolution of plastic surgery. Analysis of current innovation trends provides some insight into which technology domains are the most active.

  1. Fifty years ago: the Vaiont night

    Directory of Open Access Journals (Sweden)

    Valerio Spagna

    2012-07-01

    Full Text Available A geologist at the beginning of his career in the early 1960’s was a teacher of mineralogy and geology at the Agordo “Follador” Mining Institute in the Dolomites area. It was 50 years ago now when he observed the building of the Vaiont dam, and here he tells us of the night of October 9, 1963, when he rushed to the Piave Valley together with the first-aid teams, to confront the remains of Longarone. Did the dam collapse? Everybody thinks so, but the moon was not shining enough to allow an understanding of what had happened. It was only the first faint light of dawn that revealed that the dam was still standing: it was only edged by the water, from the shaping of the tremendous wave that was raised by the Mount Toc landslide when it entered the basin at 100 km/h. The dam edge contributed to the projection of the wave onto the opposite slopes, where once the water mass was released from the narrow Vaiont canyon, it raised solidly into the air, grazing the Casso village and precipitated as a massive block on the Longarone area. Everybody looked upwards with hate and despair, at the residual water streamlets that were overflowing along the concrete wall of the dam. Over the white bare esplanade people appeared extremely small. Pitiful people, gathered around the bodies wrenched from the devastated houses, denuded and buried in the mud.

  2. Atoms for Peace after Fifty Years

    Energy Technology Data Exchange (ETDEWEB)

    Joeck, N; Lehman, R; Vergino, E; Schock, R

    2004-03-15

    President Eisenhower's hopes for nuclear technology still resonate, but the challenges to fulfilling them are much different today. On December 8, 1953, President Eisenhower, returning from his meeting with the leaders of Britain and France at the Bermuda Summit, flew directly to New York to address the United Nations General Assembly. His presentation, known afterwards as the ''Atoms for Peace'' speech, was bold, broad, and visionary. Eisenhower highlighted dangers associated with the further spread of nuclear weapons and the end of the thermonuclear monopoly, but the president also pointed to opportunities. Earlier that year, Stalin had died and the Korean War armistice was signed. Talks on reunification of Austria were about to begin. The speech sought East-West engagement and outlined a framework for reducing nuclear threats to security while enhancing the civilian benefits of nuclear technology. One specific proposal offered to place surplus military fissile material under the control of an ''international atomic energy agency'' to be used for peaceful purposes, especially economic development. Eisenhower clearly recognized the complex interrelationships between different nuclear technologies and the risks and the benefits that accrue from each. The widespread use of civilian nuclear technology and absence of any use of a nuclear weapon during the next half-century reflects success in his approach. Today, the world faces choices about nuclear technology that have their parallels in the Eisenhower calculus and its legacy. Although his specific fissile material proposal was never implemented, his broader themes gave impetus to agreements such as the nuclear Non-Proliferation Treaty (NPT) and institutions such as the International Atomic Energy Agency (IAEA). The resulting governance process has promoted some and restricted other nuclear technology. Perhaps even more influential was Eisenhower's overarching

  3. Fifty years of Jaynes-Cummings physics

    Science.gov (United States)

    Greentree, Andrew D.; Koch, Jens; Larson, Jonas

    2013-11-01

    electromagnetic modes, arrays of coupled cavities [5-7], and optomechanical systems [8] have further enriched the physics of the Jaynes-Cummings model. From the early interests in masers and the consistent quantum description of radiation and atom-photon interaction, the Jaynes-Cummings model has evolved into a cornerstone of quantum state engineering [9]. The authors of this editorial had not been born when Jaynes and Cummings wrote their remarkable paper. It is, therefore, a special honour for us to be able to draw the reader's attention to the accompanying reminiscence contributed by Frederick Cummings where he gives us a glimpse of the early history of the Jaynes-Cummings model from his perspective [11]. By now, the original 1963 paper by Jaynes and Cummings has gathered numerous citations and, at the time of writing, the number of articles involving Jaynes-Cummings physics is approaching 15 000.1 This special issue does not attempt to review this impressive wealth of research. The interested reader, however, is urged to consult the definitive article by Shore and Knight [10] for a comprehensive review of the first 30 years of Jaynes-Cummings physics. The collection of 26 papers presented in this issue, showcases a snapshot of some of the most recent and continuing research devoted to Jaynes-Cummings physics. We begin our special issue with Professor Cumming's recollections [11]. We then have six papers on quantum information aspects of the Jaynes-Cummings model [12-17]. The next topic includes seven papers on the Dicke and generalized Jaynes-Cummings models [18-24], followed by six papers on circuit QED, which is one of the most important experimental frameworks for Jaynes-Cummings systems [25-30]. Finally, we have six papers on the extension to many cavities, the Jaynes-Cummings-Hubbard model [31-36]. The snapshot of research captured in this special issue illustrates the unifying language provided by the Jaynes-Cummings model, tying together research in a number of

  4. EDITORIAL: Semiconductor lasers: the first fifty years Semiconductor lasers: the first fifty years

    Science.gov (United States)

    Calvez, S.; Adams, M. J.

    2012-09-01

    Anniversaries call for celebrations. Since it is now fifty years since the first semiconductor lasers were reported, it is highly appropriate to celebrate this anniversary with a Special Issue dedicated to the topic. The semiconductor laser now has a major effect on our daily lives since it has been a key enabler in the development of optical fibre communications (and hence the internet and e-mail), optical storage (CDs, DVDs, etc) and barcode scanners. In the early 1960s it was impossible for most people (with the exception of very few visionaries) to foresee any of these future developments, and the first applications identified were for military purposes (range-finders, target markers, etc). Of course, many of the subsequent laser applications were made possible by developments in semiconductor materials, in the associated growth and fabrication technology, and in the increased understanding of the underlying fundamental physics. These developments continue today, so that the subject of semiconductor lasers, although mature, is in good health and continues to grow. Hence, we can be confident that the pervasive influence of semiconductor lasers will continue to develop as optoelectronics technology makes further advances into other sectors such as healthcare, security and a whole host of applications based on the global imperatives to reduce energy consumption, minimise environmental impact and conserve resources. The papers in this Special Issue are intended to tell some of the story of the last fifty years of laser development as well as to provide evidence of the current state of semiconductor laser research. Hence, there are a number of papers where the early developments are recalled by authors who played prominent parts in the story, followed by a selection of papers from authors who are active in today's exciting research. The twenty-fifth anniversary of the semiconductor laser was celebrated by the publication of a number of papers dealing with the early

  5. Fifty years of Cuba's medical diplomacy: from idealism to pragmatism.

    Science.gov (United States)

    Feinsilver, Julie M

    2010-01-01

    Medical diplomacy, the collaboration between countries to simultaneously produce health benefits and improve relations, has been a cornerstone of Cuban foreign policy since the outset of the revolution fifty years ago. It has helped Cuba garner symbolic capital (goodwill, influence, and prestige) well beyond what would have been possible for a small, developing country, and it has contributed to making Cuba a player on the world stage. In recent years, medical diplomacy has been instrumental in providing considerable material capital (aid, credit, and trade), as the oil-for-doctors deals with Venezuela demonstrates. This has helped keep the revolution afloat in trying economic times. What began as the implementation of the one of the core values of the revolution, namely health as a basic human right for all peoples, has continued as both an idealistic and a pragmatic pursuit. This article examines the factors that enabled Cuba to conduct medical diplomacy over the past fifty years, the rationale behind the conduct of this type of soft power politics, the results of that effort, and the mix of idealism and pragmatism that has characterized the experience. Moreover, it presents a typology of medical diplomacy that Cuba has used over the past fifty years.

  6. Women, Fertility and Economics: Fifty Years of Research

    OpenAIRE

    Felipe Del Río; Nelson Alvis; Martha Yánez; Raúl Quejada; Karina Acevedo

    2010-01-01

    This paper provides a systematic review of the scientific literature on fertility and its relationship with economics. We explore theoretical and empirical frameworks developed in the last fifty years, emphasizing on the classical (Becker, Easterling) and unorthodox approaches (Bongaarts, Iannaccone, Lehrer). This literature review focused on journals of economics, sociology and demography indexed in the Journal Storage database (JSTOR), Elsevier’s research database (ScienceDirect), Elton B. ...

  7. Fifty years of mathematical physics selected works of Ludvig Faddeev

    CERN Document Server

    Niemi, Antti J

    2016-01-01

    This unique volume summarizes with a historical perspective several of the major scientific achievements of Ludwig Faddeev, with a foreword by Nobel Laureate C N Yang. The volume that spans over fifty years of Faddeev's career begins where he started his own scientific research, in the subject of scattering theory and the three-body problem. It then continues to describe Faddeev's contributions to automorphic functions, followed by an extensive account of his many fundamental contributions to quantum field theory including his original article on ghosts with Popov. Faddeev's contributions to soliton theory and integrable models are then described, followed by a survey of his work on quantum groups. The final scientific section is devoted to Faddeev's contemporary research including articles on his long-term interest in constructing knotted solitons and understanding confinement. The volume concludes with his personal view on science and mathematical physics in particular.

  8. Modigliani's life-cycle theory of savings fifty years later

    Directory of Open Access Journals (Sweden)

    Mauro Baranzini

    2005-01-01

    Full Text Available In the 1950s, Modigliani proposed a theory of spending in which people make intelligent choices about their spending at each age limited by the resources available over their lives. By using assets and debts, working people can provide for their retirement and tailor their spending to their needs at each age independent of income at each age. The theory predicts that national saving depends on the growth of national income, not its level, and that aggregate wealth depends on the length of retirement. Fifty years later, the life-cycle hypothesis remains an essential part of economists' thinking. Without it, we would have much less to say about the private and public provision of social security, the effects of the stock market on the economy, the effects of demographic change on national saving, the role of saving in economic growth, and the determinants of national wealth.

  9. Fifty Years of Climate Curricular Confusion and Pedagogical Gaps

    Science.gov (United States)

    McCaffrey, M. S.; Buhr, S. S.; Niepold, F.

    2008-12-01

    The processes of weather and climate, including the greenhouse effect and the potential for significant, even catastrophic human impacts on the climate system, were sufficiently understood in 1958 during the International Geophysical Year that the authors of the science education booklet, Planet Earth, The Mystery with 100,000 Clues, published by the U.S. National Academy of Sciences, were confident to predict that continued emissions of carbon dioxide into the atmosphere could, in time, melt icecaps and glaciers and rise sea levels. This important scientific insight was further studied by climatologists, but is largely missing as an integral, important component of science education. Now, fifty years later, with a global population that has doubled, fossil fuel emissions that have tripled, and current energy consumption and emission trajectories that are above the IPCC Business as Usual scenario, leading politicians still doubt that our global economy can impact the climate system. NRC estimates that up to 40 percent of the approximately $10 trillion U.S. economy is affected by weather and climate events annually, making it a crucial if not dominant factor in our economic well-being, particularly for future generations. Despite the long term and short term importance of climate in our lives, society is essentially illiterate about climate science and confused about the connections between energy, economy and climate, as numerous public opinion polls and studies have shown. A key reason is that education programs and pedagogical content knowledge focusing on the basics of climate, including natural variability as well as human induced climate change, are largely missing from K12 and undergraduate education. Climate has fallen through disciplinary cracks, been avoided because of perceived controversy, and neglected because most educators lack training or expertise in the subject matter. With a focus on climate in formal education, this paper will provide an overview

  10. The Proton Synchrotron, going strong at fifty years

    CERN Multimedia

    Django Manglunki

    It was on the evening of 24 November 1959 that an incredulous Hildred Blewett, on detachment to CERN from the Brookhaven laboratory, exclaimed “Yes! We’re through transition!” The first beam of ten billion protons had not only broken through the 5.2 GeV barrier but gone on all the way to 24 GeV, the machine’s top energy at that time.   An operational screenshot from the PS, taken on its 50th anniversary. The three white peaks depict different phases (cycles) of the PS’s operation. In the first and third cycle, the PS is producing a very low-intensity beam for LHC commissioning. In the second cycle, protons are being spilled out for use in the East Area. Fifty years ago the PS, the first strong-focusing proton synchrotron using alternating gradient technology, first began to circulate beams at an unprecedented level of energy. Over the years, a complex of linear and circular accelerators and storage rings grew up around the PS. In the mid-1990s ...

  11. Fifty years of numerical modeling of baroclinic ocean

    Science.gov (United States)

    Sarkisyan, A. S.

    2012-02-01

    This paper presents a brief critical analysis of the main historical stages of numerical modeling for the last fifty years. It was a half a century ago that the numerical simulation of an actual baroclinic ocean was initiated by the author and his students [1, 2]. In meteorology, studies on the numerical modeling of a baroclinic atmosphere existed much earlier [21, 22]. Despite this, a similar move in oceanography was met with strong resistance. At that time, there were many studies on the calculation of the total mass transport. The founders of this field, V.B. Shtokman, H. Sverdrup, and W. Munk, were mistaken in believing that they addressed baroclinic models of the ocean. The author preferred works by V. Ekman [12] and I. Sandström and B. Helland-Hansen [19]. A generalization of recent studies made it possible to come to some conclusions on the need to use the level of the free oceanic surface as a basis rather than the function of total mass transport, on the role of the baroclinic β effect (BARBE), on the joint effect of baroclinicity and bottom relief (JEBAR), etc. The author conditionally divides these fifty years into the following three stages. (1) The first stage was 1961-1969, when the author and his students performed almost exclusively diagnostic and adaptation calculations of climatic characteristics. (2) The second stage began with papers by K. Bryan [23] and his students. This is an important and promising stage involving mainly prognostic studies and four-dimensional analysis. The major advances in modeling at this stage (the Gulf Stream separation point [61], the Kuroshio seasonal evolution [63], the formation of the cold intermediate layer in the Black Sea [80], the subsurface countercurrent in the Caspian Sea [25], the realistic four-dimensional analysis of the Kara Sea [60], etc.) were due to high-resolution and/or data assimilation with an adequate period of integration. (3) The third stage began with the activities of international

  12. Revisiting fifty years of research on pheromone signaling in ciliates.

    Science.gov (United States)

    Luporini, Pierangelo; Pedrini, Bill; Alimenti, Claudio; Vallesi, Adriana

    2016-08-01

    Among protists, pheromones have been identified in a great variety of algal species for their activity in driving gamete-gamete interactions for fertilization. Analogously in ciliates, pheromones have been identified for their activity in inducing the sexual phenomenon of conjugation. Although this identification was pioneered by Kimball more than fifty years ago, an effective isolation and chemical characterization of ciliate pheromones has remained confined to species of Blepharisma, Dileptus and Euplotes. In Euplotes species, in which the molecular structures have been determined, pheromones form species-specific families of structurally homologous helical, cysteine-rich, highly-stable proteins. Being structurally homologous, they can bind cells in competition with one another, raising interesting functional analogies with the families of growth factors and cytokines that regulate cell differentiation and development in higher organisms. In addition to inducing conjugation by binding cells in heterologous fashion, Euplotes pheromones act also as autocrine growth factors by binding to, and promoting the vegetative reproduction of the same cells from which they originate. This autocrine activity is most likely primary, providing a concrete example of how the original function of a molecule can be obscured during evolution by the acquisition of a new one.

  13. DMPD: Fifty years of interferon research: aiming at a moving target. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 16979566 Fifty years of interferon research: aiming at a moving target. Vilcek J. I...mmunity. 2006 Sep;25(3):343-8. (.png) (.svg) (.html) (.csml) Show Fifty years of interferon research: aiming... at a moving target. PubmedID 16979566 Title Fifty years of interferon research: aiming at a moving target.

  14. Fifty Years of Space Weather Forecasting from Boulder

    Science.gov (United States)

    Berger, T. E.

    2015-12-01

    The first official space weather forecast was issued by the Space Disturbances Laboratory in Boulder, Colorado, in 1965, ushering in an era of operational prediction that continues to this day. Today, the National Oceanic and Atmospheric Administration (NOAA) charters the Space Weather Prediction Center (SWPC) as one of the nine National Centers for Environmental Prediction (NCEP) to provide the nation's official watches, warnings, and alerts of space weather phenomena. SWPC is now integral to national and international efforts to predict space weather events, from the common and mild, to the rare and extreme, that can impact critical technological infrastructure. In 2012, the Strategic National Risk Assessment included extreme space weather events as low-to-medium probability phenomena that could, unlike any other meteorogical phenomena, have an impact on the government's ability to function. Recognizing this, the White House chartered the Office of Science and Technology Policy (OSTP) to produce the first comprehensive national strategy for the prediction, mitigation, and response to an extreme space weather event. The implementation of the National Strategy is ongoing with NOAA, its partners, and stakeholders concentrating on the goal of improving our ability to observe, model, and predict the onset and severity of space weather events. In addition, work continues with the research community to improve our understanding of the physical mechanisms - on the Sun, in the heliosphere, and in the Earth's magnetic field and upper atmosphere - of space weather as well as the effects on critical infrastructure such as electrical power transmission systems. In fifty years, people will hopefully look back at the history of operational space weather prediction and credit our efforts today with solidifying the necessary developments in observational systems, full-physics models of the entire Sun-Earth system, and tools for predicting the impacts to infrastructure to protect

  15. [Fifty years of treating stuttering in young children].

    Science.gov (United States)

    Franken, M C

    2004-08-14

    Developmental stuttering involves a disruption in the smooth connection of sounds or syllables that is characterised by multiple interruptions within a word, such as repetitions of sounds, syllables and parts of words, elongation of words and blockades. During the course of the past fifty years, three phases can be distinguished in the management of developmental stuttering, characterised by a shift in stress from the environmental factors to the role of the organic, i.e. non-psychological, factors. Initially, the parents of toddlers and pre-school children were advised to pay no attention to stuttering behaviour. Then the problem would disappear the quickest of its own accord. After 1985, the stress came to be placed on reducing the level of expectations, for example by speaking to the child more slowly and using shorter and less complex sentences. Another new aspect was that the parents learned to discuss stuttering with the child in a sympathetic and accepting manner. Since 2000, an approach has been introduced in the Netherlands in which parents are taught to respond verbally to both fluent and non-fluent speech. Emphasis is given to rewarding fluent speech, such as in the Australian Lidcombe Program, but the parents are also taught to react to stuttered speech once in a while. At present, early treatment is accepted as a way of preventing chronic stuttering, even if this means that some children will be treated that would have recovered in any case and even though the exact yield is not yet clear. Clinical practice shows that early treatment almost always succeeds in limiting the severity of stuttering to a mild form.

  16. Fifty years of fuzzy logic and its applications

    CERN Document Server

    Rishe, Naphtali; Kandel, Abraham

    2015-01-01

    This book presents a comprehensive report on the evolution of Fuzzy Logic since its formulation in Lotfi Zadeh’s seminal paper on “fuzzy sets,” published in 1965. In addition, it features a stimulating sampling from the broad field of research and development inspired by Zadeh’s paper. The chapters, written by pioneers and prominent scholars in the field, show how fuzzy sets have been successfully applied to artificial intelligence, control theory, inference, and reasoning. The book also reports on theoretical issues; features recent applications of Fuzzy Logic in the fields of neural networks, clustering, data mining, and software testing; and highlights an important paradigm shift caused by Fuzzy Logic in the area of uncertainty management. Conceived by the editors as an academic celebration of the fifty years’ anniversary of the 1965 paper, this work is a must-have for students and researchers willing to get an inspiring picture of the potentialities, limitations, achievements and accomplishments...

  17. Editorial: “Fifty years Annals of Forest Science”

    OpenAIRE

    Leban, Jean-Michel; Peiffer, Marianne; Bontemps, Jean-Daniel; Dreyer, Erwin

    2016-01-01

    Annals of Forest Science is publishing a series of review papers to celebrate 50 years of activities as a journal in forest and wood science. The reviews emphasize the extent to which forest and wood sciences changed and developed as a large array of disciplines devoted to complex objects with sometimes many conflicting issues.

  18. Marriage and Fertility in Tianjin, China: Fifty Years of Transition.

    Science.gov (United States)

    Pasternak, Burton

    A report of research conducted in Tianjin, People's Republic of China (September 1981-January 1982) describes and analyses changes in family structure, marriage, post-marital residence, and fertility in a neighborhood of factory workers over a 50-year period. Social and economic changes such as delayed marriage, increased access to education, and…

  19. Fifty years of CERN history in the spotlight

    CERN Multimedia

    2004-01-01

    The programme of events for CERN's Golden Jubilee year was officially unveiled at a press conference on 8 March. The first of these events took place the following day, when the Swiss commemorative postage stamp issued in the Laboratory's honour went on sale in post offices throughout Switzerland.

  20. [Fifty years of mortality or the result of social inequality].

    Science.gov (United States)

    Jimenez Ornelas, R

    1993-01-01

    An average of 30 years has been added to Mexican life expectancy in the past five decades. Women and men born in 1940 had life expectancies of 41.5 and 39.5 years, respectively, compared to 72.8 and 66.7 in 1990. Mortality declined most sharply between 1940 and 1960, and declined at varying rates in the subsequent decades. In the decade from 1980 to 1990, the mortality decline slowed. The differential in life expectancy between men and women amounted to 6.2 years in 1980 and 6.1 in 1990. The high life expectancy of women means that future advances will be more difficult to achieve. The greater survival of Mexicans over the five decades is due to improvements in living conditions, advances in preventive and curative medicine, and social policy. The slower pace of mortality decline in the past decade may perhaps have been due to deteriorating living conditions, reduced priority accorded to social policies in the areas of health and education, and declining real incomes. Mexican health, education, and other social policies have favored the urban and industrial centers, increasing regional disparities. A comparison of life expectancies in Oaxaca, one of the most impoverished states of Mexico, and Puebla, which has somewhat better conditions, with life expectancies in the wealthy state of Nuevo Leon and the Federal District demonstrates the influence of the level of development on life expectancy. Life expectancy in 1990 in Oaxaca and Puebla was the equivalent of that for all of Mexico ten years earlier. Men in Oaxaca live five years less on average than men in Nuevo Leon. But the gain in life expectancy for males was higher in Oaxaca between 1980 and 1990 than in the other states.

  1. Water chemistry: fifty years of change and progress.

    Science.gov (United States)

    Brezonik, Patrick L; Arnold, William A

    2012-06-05

    Water chemistry evolved from early foundations in several related disciplines. Although it is difficult to associate a precise date to its founding, several events support the argument that the field as we know it today developed in the mid-20th century--at the dawn of the "environmental era"--that is, ∼1960. The field in its modern incarnation thus is about 50 years old. In celebration of this half-centenary, we examine here the origins of water chemistry, how the field has changed over the past 50 years, and the principal driving forces for change, focusing on both the "practice" of water chemistry and ways that teaching the subject has evolved.

  2. Fifty years of wilderness science: An international perspective

    Science.gov (United States)

    Steve Carver; Steve McCool; Zdenka Krenova; Mark Fisher; Stephen. Woodley

    2014-01-01

    The 50th Anniversary of the U.S. Wilderness Act is a cause for celebration, not least of which is the scientific use recognized in Section 4(b) of the act. This year also marks the 20th anniversary of publication of the International Journal of Wilderness (IJW). IJW plays a unique role in wilderness stewardship, science, and advocacy, providing a forum for presentation...

  3. Bibliometric analysis of fifty years of physica status solidi

    Energy Technology Data Exchange (ETDEWEB)

    Marx, Werner [Max Planck Institute for Solid State Research, Stuttgart (Germany); Hoffmann, Dieter [Max Planck Institute for the History of Sciences, Berlin (Germany)

    2011-12-15

    Bibliometric methods are used to analyze quantitatively the journal physica status solidi (pss) 50 years after its inception. First, the coverage of the journal by the relevant citation indices accessible under the Web of Science (WoS) and the field-specific INSPEC database is examined. The number of papers published per year by the journal as a whole and by the specific pss series is given. The time evolution of the pss output in terms of papers per year is compared with the output evolution of some major competing journals in the field of condensed-matter physics. The top-12 most frequently cited pss papers published within the complete time period 1961-2010 and within the two separate time periods 1974-1989 and 1990-2010 (before and after the German reunification) are listed. The citation time curves (citation history) of the three most frequently cited pss papers are presented. Furthermore, the Journal Impact Factors (JIFs) of the pss journal series (a) and (b) are discussed and their time evolution is shown. Moreover, the distribution of the pss papers over their document types and the authors is given. The countries of authors are ranked for the complete time period 1961-2010 as well as for the time periods 1973-1989 and 1990-2010. The complete ensemble of the citing papers of the pss papers is analyzed and discussed. The journals citing most often the pss papers published in the year 2000 are listed. Finally, the distribution of the pss papers over the various subject areas and classification terms based on the INSPEC database is tabled. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  4. Fifty years of the CERN Proton Synchrotron Volume 2

    CERN Document Server

    Gilardoni, Simone; CERN. Geneva; Burnet, Jean-Paul; Carli, Christian; Chanel, Michel; Garoby, Roland; Giovannozzi, Massimo; Hancock, Steven; Haseroth, Helmut; Hübner, Kurt; Küchler, Detlef; Lewis, Julian; Lombardi, Alessandra; Martini, Michel; Maury, Stephan; Métral, Elias; Möhl, Dieter; Plass, Günther; Rinolfi, Louis; Scrivens, Richard; Steerenberg, Rende; Steinbach, Charles; Vretenar, Maurizio; Zickler, Thomas

    2013-08-12

    This report sums up in two volumes the first 50 years of operation of the CERN Proton Synchrotron. After an introduction on the genesis of the machine, and a description of its magnet and powering systems, the first volume focuses on some of the many innovations in accelerator physics and instrumentation that it has pioneered, such as transition crossing, RF gymnastics, extractions, phase space tomography, or transverse emittance measurement by wire scanners. The second volume describes the other machines in the PS complex: the proton linear accelerators, the PS Booster, the LEP pre-injector, the heavy-ion linac and accumulator, and the antiproton rings.

  5. Fifty years of the CERN Proton Synchrotron Volume 1

    CERN Document Server

    CERN. Geneva; Carli, Christian; Chanel, Michel; Garoby, Roland; Gilardoni, Simone; Giovannozzi, Massimo; Hancock, Steven; Haseroth, Helmut; Hübner, Kurt; Küchler, Detlef; Lewis, Julian; Lombardi, Alessandra; Manglunki, Django; Martini, Michel; Maury, Stephan; Métral, Elias; Möhl, Dieter; Plass, Günther; Rinolfi, Louis; Scrivens, Richard; Steerenberg, Rende; Steinbach, Charles; Vretenar, Maurizio; Zickler,Thomas

    2011-01-01

    This report sums up in two volumes the first 50 years of operation of the CERN Proton Synchrotron. After an introduction on the genesis of the machine, and a description of its magnet and powering systems, the first volume focuses on some of the many innovations in accelerator physics and instrumentation that it has pioneered, such as transition crossing, RF gymnastics, extractions, phase space tomography, or transverse emittance measurement by wire scanners. The second volume describes the other machines in the PS complex: the proton linear accelerators, the PS Booster, the LEP pre-injector, the heavy-ion linac and accumulator, and the antiproton rings.

  6. Fifty years of IAA History Symposia (1967-2016)

    Science.gov (United States)

    Skoog, A. Ingemar; Hall, R. Cargill

    2017-05-01

    The International Academy of Astronautics (IAA) Symposia on the History of Rocketry and Astronautics have been held annually at the International Astronautical Congresses since 1967. During these past 50 years nearly 800 papers have been presented and subsequently published in the proceedings. With a 20-year rule imposed for historical presentations, the first 10 symposia concentrated on pre-World War II and early 1950s activities. A surprisingly large number of papers on early, less well-known Soviet-Russian contributions to rocketry and astronautics were presented in the first symposia, despite the ongoing Space Race between the U.S and USSR. Another important element in these symposia involved memoir papers offered by pre- and post-war rocket and astronautics pioneers from many countries, and the participation of many of these pioneers in person. In sum, the history of national space and rocket projects from some 40 countries were presented over the years in IAA History Symposia. These 50 symposia have provided a platform for scholars and professional and non-professional historians to meet and discuss the history of rocketry and astronautics, and to personally interview many space pioneers, most of whom today are deceased. Their personal recollections have since been shared with a large audience. Over time, IAA history papers divided into recognizable periods: ancient times through the 19th century, and the 20th and 21st centuries, which separate among actions and events that took place before 1945, in 1945 to 1957, and after 1957 (which marked the beginning of the space age). Proceedings of the IAA History Symposia have been published in English, ultimately in the History Series of the American Astronautical Society (AAS) and its publishing arm, Univelt Inc., under an agreement secured with the IAA. This paper presents an overview of the IAA History Symposia. It examines the early years of the history committee and its first symposium, the evolution of

  7. [From conventional cytogenetics to microarrays. Fifty years of Philadelphia chromosome].

    Science.gov (United States)

    Hernández, Jesús M; Granada, Isabel; Solé, Francesc

    2011-07-23

    In 1960 Ph-chromosome was found associated with the presence of chronic myelogenous leukemia. In these 50 years an increasing number of cytogenetic abnormalities have been found associated with hematological malignancies. The presence of these abnormalities is not only important for the diagnosis of the patient, but it also contributes to the prognosis of patients with leukemia or lymphoma. For this reason the WHO classification of hematological disease has included these studies for the correct characterization of leukemias and lymphomas. In addition, the use of FISH and micromatrix methodologies have refined the genetic lesions present in these malignancies. The cytogenetic changes observed also provide further information in relation to the therapy.

  8. The right to health fifty years on: still skeptical?

    Science.gov (United States)

    Kirby, M

    1999-01-01

    The drafting of the Universal Declaration of Human Rights was a crucial step in the recognition of a legal right to health. Although the past 50 years have revealed weaknesses in the Declaration, it has been an important catalyst for social and legal change worldwide and for new thinking about public health. Recently, the struggle against the HIV/AIDS epidemic has taught us that protecting the human rights of those most at risk is, in fact, a most effective means of preventing the spread of HIV. Traditional public health problems, as well as those involving new biotechnologies, must today be addressed with specific attention to human rights.

  9. Fifty years of fuel quality and vehicle emissions

    Energy Technology Data Exchange (ETDEWEB)

    Rose, K. [CONCAWE, Brussels (Belgium)

    2013-04-01

    In the late 1970s, with growing emphasis on urban air quality in Europe, CONCAWE embarked on new research related to fuels and vehicles. After only a few years, it became clear that fuel properties and specifications would be increasingly important to the future of the European refining industry, and considerable research was completed in the 1970s to better understand the impact of fuel composition on vehicle performance and emissions. This early work led to the formation of the first Fuels and Emissions Management Group (FEMG) in 1982, almost 20 years after the formation of the CONCAWE Association. Since these early days, FEMG has been responsible for ensuring CONCAWE's strategic outlook on future vehicle and fuel developments, monitoring regulatory and vehicle developments, and overseeing a diverse portfolio of fuel quality and vehicle emissions research. Since the 1980s, tremendous progress has been made in improving European air quality, in part by reducing emissions from road transport and other sectors, and major improvements in European fuel qualities have contributed to these reductions. Nevertheless, many challenges are still ahead, especially further reductions in pollutant emissions from vehicles while also reducing greenhouse gas (GHG) emissions from transport. In the near-term, these GHG reductions will largely come from improvements in engine and vehicle fuel consumption and by blending of GHG-reducing bio-blending components. Dealing with these challenges to fuel quality and performance will require a continuing focus on CONCAWE's founding principles: sound science, cost effectiveness and transparency.

  10. Fifty years of the Korean Society for Parasitology.

    Science.gov (United States)

    Cho, Seung-Yull

    2009-10-01

    In 1959, the Korean Society for Parasitology was founded by clinical scientists, specialists of public health, and 5 core parasitologists with experience in American science and medicine. The Society this year celebrates its 50th anniversary. Due to public health importance at the time of foundation, medical parasitology was the main stream for next 3 decades. Domestic problems of niche parasitic diseases, unlisted in 6 tropical diseases of major importance, had been studied by own efforts. To cope with the demand of parasite control, evaluation system for control activity was built up. Control activity against soil-transmitted nematodes, conducted for almost 3 decades, was evaluated as a success. Evaluation of praziquantel efficacy for clonorchiasis, paragonimiasis, and neurocysticercosis, population dynamics of Ascaris lumbricoides infection in a situation of continuous reinfections, diagnostic modalities of antibody tests combined with brain imaging developed for helminthiasis of the central nervous system and researches on intestinal trematodes were achievements in the first 30 years. During the recent 2 decades, science researches, such as cell and molecular biology of parasites and immunology of parasitic infections have been studied especially on parasitic allergens and proteolytic and anti-oxidant enzymes. Experiences of international cooperation for world health have been accumulated and would be expanded in the future.

  11. [Fifty years of cooperation--FEBS and Polish Biochemical Society].

    Science.gov (United States)

    Barańska, Jolanta

    2014-01-01

    This year, the Federation of European Biochemical Societies (FEBS) celebrates its 50th anniversary. The Polish Biochemical Society, represented by the Society's President, Kazimierz Zakrzewski, was a founding member of the organization. The text presents a history of collaboration between FEBS and Polish Biochemical Society, the participation of Polish Biochemical Society members in different FEBS activities, as well as the role they played in running the Federation. Author describes FEBS Congresses which taken place in Warsaw, the first 3rd FEBS Meeting in 1966 and then 29th Congress in 2004. The profiles of Jakub Karol Parnas, the founding father of the Polish biochemistry and some crucial Presidents of the Society, are also presented. The text describes Parnas Conferences, organized jointly by Polish and Ukrainian Biochemical Societies from 1996, and growing from 2011 into three-nation event with participation of Ukrainian, Israeli and Polish scientists, largely due to significant help from FEBS. Summarizing the last few years, author judge the cooperation between the Federation and the Polish Biochemical Society as optimal.

  12. Fifty Years of the Spectrum Problem: Survey and New Results

    CERN Document Server

    Durand, Arnaud; Makowsky, Johann; More, Malika

    2009-01-01

    In 1952, Heinrich Scholz published a question in the Journal of Symbolic Logic asking for a characterization of spectra, i.e., sets of natural numbers that are the cardinalities of finite models of first order sentences. G\\"unter Asser asked whether the complement of a spectrum is always a spectrum. These innocent questions turned out to be seminal for the development of finite model theory and descriptive complexity. In this paper we survey developments over the last 50-odd years pertaining to the spectrum problem. Our presentation follows conceptual developments rather than the chronological order. Originally a number theoretic problem, it has been approached in terms of recursion theory, resource bounded complexity theory, classification by complexity of the defining sentences, and finally in terms of structural graph theory. Although Scholz' question was answered in various ways, Asser's question remains open. One appendix paraphrases the contents of several early and not easily accesible papers by G. Ass...

  13. Changes in sunflower breeding over the last fifty years

    Directory of Open Access Journals (Sweden)

    Vear Felicity

    2016-03-01

    Full Text Available This article discusses changes in sunflower breeding objectives since the introduction of hybrid varieties 50 years ago. After a reminder of the importance of some early programmes, Canadian in particular, the present situation for each breeding objective is compared with those encountered earlier. Breeding for yield has changed from maximum possible yield under intensive agriculture to yield with resistance to abiotic stresses, moderate droughts and shallow soils in particular, helped by collaboration with agronomists to produce crop models. Breeding for oil has changed from quantity to quality and the value of seed meal is again becoming economically important. Necessary disease resistances vary with agronomic practises and selection pressure on pathogens according to varietal genetics. The possibilities of new types of sunflower are also discussed. Advances in genomics will change breeding procedures, but with rapidly changing molecular techniques, international collaboration is particularly important.

  14. Perspectives on Erving Goffman's "Asylums" fifty years on.

    Science.gov (United States)

    Adlam, John; Gill, Irwin; Glackin, Shane N; Kelly, Brendan D; Scanlon, Christopher; Mac Suibhne, Seamus

    2013-08-01

    Erving Goffman's "Asylums" is a key text in the development of contemporary, community-orientated mental health practice. It has survived as a trenchant critique of the asylum as total institution, and its publication in 1961 in book form marked a further stage in the discrediting of the asylum model of mental health care. In this paper, some responses from a range of disciplines to this text, 50 years on, are presented. A consultant psychiatrist with a special interest in cultural psychiatry and mental health legislation, two collaborating psychotherapists in adult and forensic mental health, a philosopher, and a recent medical graduate, present their varying responses to the text. The editors present these with the hope of encouraging further dialogue and debate from service users, carers, clinicians, and academics and researchers across a range of disciplines.

  15. Poly(N-isopropylacrylamide) Phase Diagrams: Fifty Years of Research.

    Science.gov (United States)

    Halperin, Avraham; Kröger, Martin; Winnik, Françoise M

    2015-12-14

    In 1968, Heskins and Guillet published the first systematic study of the phase diagram of poly(N-isopropylacrylamide) (PNIPAM), at the time a "young polymer" first synthesized in 1956. Since then, PNIPAM became the leading member of the growing families of thermoresponsive polymers and of stimuli-responsive, "smart" polymers in general. Its thermal response is unanimously attributed to its phase behavior. Yet, in spite of 50 years of research, a coherent quantitative picture remains elusive. In this Review we survey the reported phase diagrams, discuss the differences and comment on theoretical ideas regarding their possible origins. We aim to alert the PNIPAM community to open questions in this reputably mature domain.

  16. Fifty years of federal radioactive waste management: Policies and practices

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, R.G.

    1997-04-01

    This report provides a chronological history of policies and practices relating to the management of radioactive waste for which the US Atomic Energy Commission and its successor agencies, the Energy Research and Development Administration and the Department of Energy, have been responsible since the enactment of the Atomic Energy Act in 1946. The defense programs and capabilities that the Commission inherited in 1947 are briefly described. The Commission undertook a dramatic expansion nationwide of its physical facilities and program capabilities over the five years beginning in 1947. While the nuclear defense activities continued to be a major portion of the Atomic Energy Commission`s program, there was added in 1955 the Atoms for Peace program that spawned a multiplicity of peaceful use applications for nuclear energy, e.g., the civilian nuclear power program and its associated nuclear fuel cycle; a variety of industrial applications; and medical research, diagnostic, and therapeutic applications. All of these nuclear programs and activities generated large volumes of radioactive waste that had to be managed in a manner that was safe for the workers, the public, and the environment. The management of these materials, which varied significantly in their physical, chemical, and radiological characteristics, involved to varying degrees the following phases of the waste management system life cycle: waste characterization, storage, treatment, and disposal, with appropriate transportation linkages. One of the benefits of reviewing the history of the waste management program policies and practices if the opportunity it provides for identifying the lessons learned over the years. Examples are summarized at the end of the report and are listed in no particular order of importance.

  17. Chemical Hydrogeology: Fifty Years of Advances, Breakthroughs, and Innovation

    Science.gov (United States)

    Brusseau, M. L.

    2015-12-01

    Chemical hydrogeology focuses on the composition, properties, and biogeochemical processes inherent to water in subsurface environments. Multiple avenues of research coalesced in the 1960's to foment the development of chemical hydrogeology as a distinct field. In the intervening 50 years, chemical hydrogeology principles have been applied to innumerable issues and problems, and concomitantly, the field has continually experienced advances, breakthroughs, and innovations in theory, analysis, and application. An overarching theme to chemical hydrogeology in both theory and application is integration--- integration of disciplines (interdisciplinary, multidisciplinary), integration of approaches (theoretical, experimental, analytical), and integration of scales (spatial, temporal). Chemical hydrogeology has never been more relevant and more challenged as today, as we face critical issues related to for example water scarcity and availability of clean water, impacts of energy development, production and storage, and human interactions with ecosystem services. This presentation will illustrate recent advances in chemical hydrogeology, ranging from application of advanced imaging for characterization of pore-scale multiphase systems to integrated physical and biogeochemical assessments of field-scale contaminant transport.

  18. Fifty Years of Quasars: Physical Insights and Potential for Cosmology

    CERN Document Server

    Sulentic, J W; Dultzin, D; D'Onofrio, M; del Olmo, A

    2014-01-01

    Last year (2013) was more or less the 50th anniversary of the discovery of quasars. It is an interesting time to review what we know (and don't know) about them both empirically and theoretically. These compact sources involving line emitting plasma show extraordinary luminosities extending to one thousand times that of our Milky Way in emitting volumes of a few solar system diameters (bolometric luminosity log L$_{bol} \\sim $ 44-48 [erg s$^{-1}$]: D=1-3 light months $\\sim$ $10^3$ - $10^4$ gravitational radii). The advent of 8-10 meter class telescopes enables us to study them spectroscopically in ever greater detail. In 2000 we introduced a 4D Eigenvector 1 parameters space involving optical, UV and X-Ray measures designed to serve as a 4D equivalent of the 2D Hertzsprung-Russell diagram so important for depicting the diversity of stellar types and evolutionary states. This diagram has revealed a principal sequence of quasars distinguished by Eddington ratio (proportional to the accretion rate per unit mass)...

  19. Fifty years of progress in speech understanding systems

    Science.gov (United States)

    Zue, Victor

    2004-10-01

    Researchers working on human-machine interfaces realized nearly 50 years ago that automatic speech recognition (ASR) alone is not sufficient; one needs to impart linguistic knowledge to the system such that the signal could ultimately be understood. A speech understanding system combines speech recognition (i.e., the speech to symbols conversion) with natural language processing (i.e., the symbol to meaning transformation) to achieve understanding. Speech understanding research dates back to the DARPA Speech Understanding Project in the early 1970s. However, large-scale efforts only began in earnest in the late 1980s, with government research programs in the U.S. and Europe providing the impetus. This has resulted in many innovations including novel approaches to natural language understanding (NLU) for speech input, and integration techniques for ASR and NLU. In the past decade, speech understanding systems have become major building blocks of conversational interfaces that enable users to access and manage information using spoken dialogue, incorporating language generation, discourse modeling, dialogue management, and speech synthesis. Today, we are at the threshold of developing multimodal interfaces, augmenting sound with sight and touch. This talk will highlight past work and speculate on the future. [Work supported by an industrial consortium of the MIT Oxygen Project.

  20. Marijuana: A Fifty-Year Personal Addiction Medicine Perspective.

    Science.gov (United States)

    Smith, David E

    2016-01-01

    As of September 2015, the cultivation, possession, and/or use of marijuana is illegal under U.S. federal law as a Schedule I narcotic; however, it is legal in four states and Washington, D.C. Forty-six states allow some form of medicinal marijuana or decriminalization. Marijuana has been used medicinally for thousands of years; Marijuana's regulation by law enforcement in the U.S., rather than the medical community, led to an almost complete halt to academic and scientific research after the 1930s. The late 1960s saw an upsurge in recreational marijuana use by middle-class youth, the majority of whom experienced minimal adverse effects aside from arrest and attendant legal complications. Since the mid-1990s, the use of medicinal marijuana for certain conditions has gained increasing acceptance. Stronger strains and formulations of marijuana pose a risk to the developing brains of adolescents. Within the addiction medicine community, there is currently no consensus on marijuana. In the East, the feeling is primarily that marijuana continue to be proscribed. In the West, where clinicians must face the realities of medicalization, decriminalization, and/or legalization, as well as widespread recreational use, there is more of a movement to minimize adverse effects, particularly on youth.

  1. Fifty Years of THERP and Human Reliability Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring

    2012-06-01

    In 1962 at a Human Factors Society symposium, Alan Swain presented a paper introducing a Technique for Human Error Rate Prediction (THERP). This was followed in 1963 by a Sandia Laboratories monograph outlining basic human error quantification using THERP and, in 1964, by a special journal edition of Human Factors on quantification of human performance. Throughout the 1960s, Swain and his colleagues focused on collecting human performance data for the Sandia Human Error Rate Bank (SHERB), primarily in connection with supporting the reliability of nuclear weapons assembly in the US. In 1969, Swain met with Jens Rasmussen of Risø National Laboratory and discussed the applicability of THERP to nuclear power applications. By 1975, in WASH-1400, Swain had articulated the use of THERP for nuclear power applications, and the approach was finalized in the watershed publication of the NUREG/CR-1278 in 1983. THERP is now 50 years old, and remains the most well known and most widely used HRA method. In this paper, the author discusses the history of THERP, based on published reports and personal communication and interviews with Swain. The author also outlines the significance of THERP. The foundations of human reliability analysis are found in THERP: human failure events, task analysis, performance shaping factors, human error probabilities, dependence, event trees, recovery, and pre- and post-initiating events were all introduced in THERP. While THERP is not without its detractors, and it is showing signs of its age in the face of newer technological applications, the longevity of THERP is a testament of its tremendous significance. THERP started the field of human reliability analysis. This paper concludes with a discussion of THERP in the context of newer methods, which can be seen as extensions of or departures from Swain’s pioneering work.

  2. Fifty-one Years of Hawaiian Hotspot Debate

    Science.gov (United States)

    Hofmann, A. W.; Farnetani, C. G.

    2014-12-01

    Tuzo Wilson's ground breaking realization that the progressively increasing ages of volcanism along linear chains of Pacific islands are best explained by movement of the Pacific plate over a stationary heat source was followed by Jason Morgan's physically more plausible plume theory. Hawaii, the "mother" of all plumes/hotspots, has become the focus of a continuing burden-of-proof battle about the existence of mantle plumes. The monotonic age progression of this island chain has been amply confirmed, but the hotspot locus is not perfectly fixed, and this has been taken to be a failed test of the plume model. Numerous numerical experiments in bottom-heated settings have demonstrated that plumes are a physically natural mode of convection, but antiplumers focus on the fact that in internally heated media, plumes are unlikely. Early proposals of propagating lithospheric fractures with magma tapped from the underlying asthenosphere have never been sufficiently developed to seriously compete with the convection models. Geochemists eagerly adopted the plume model and developed highly model-dependent criteria for identifying mantle plumes, but these are easily knocked down, because most geochemical tracers carry no information about the specific mantle depth being sampled. Conversely, petrological-geochemical models invoking exclusively asthenospheric magma sources have not explained how, in the absence of a Bunsen burner, high melt production can be localized in one geographic spot for 108 years. Our work has focussed on using dynamic modelling to trace the path of geochemical heterogeneities from the base of the mantle to the volcanoes. We find that large-scale heterogeneities existing in the lower thermal boundary layer are drawn into close proximity in the plume conduit and in the erupting volcanoes. Geochemistry cannot prove mantle plumes, but plumes offer a promising path to understanding the geochemistry of the deep mantle.

  3. Deterrence, denuclearization, and proliferation: Alternative visions of the next fifty years

    Energy Technology Data Exchange (ETDEWEB)

    Lehman, R.F. II

    1994-02-12

    The great library of Alexandria may have contained fewer volumes than the number which have been written on the subject of nuclear weapons in the Cold War. With the end of the Cold War, a new nuclear library is in the making. Much thought is being given to the next steps in nuclear policy, strategy, forces, arms control, and nonproliferation. For this very distinguished conference, however, I have been asked to look further ahead indeed, forward fifty-years. Prognostication is always a risky business. Detailed predictions beyond the shortest duration are difficult to label as ``scientific`` even in the social sciences. Forecasting ahead fifty years in an age of ever accelerating change would seem to be hopeless. Projecting the future of nuclear weapons, however, may not be as complex as one might think. Detailing the future fifty years from now is not necessary. We want to inform upcoming decisions by examining the possibilities, not write a history in advance of what is to happen. Our look forward con benefit from a brief look back fifty years. In retrospect, those years passed quickly, and with each additional year, analysts make them appear more simple than they seemed at the time. This paper contributes further to this process of oversimplification, as we say, ``for heuristic purposes.`` When in doubt, I have erred on the side of being provocative.

  4. Domain analysis of computational science - Fifty years of a scientific computing group

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, M.

    2010-02-23

    I employed bibliometric- and historical-methods to study the domain of the Scientific Computing group at Brookhaven National Laboratory (BNL) for an extended period of fifty years, from 1958 to 2007. I noted and confirmed the growing emergence of interdisciplinarity within the group. I also identified a strong, consistent mathematics and physics orientation within it.

  5. Fifty years of continuous improvement: (What has DOE done for analytical chemistry?)

    Energy Technology Data Exchange (ETDEWEB)

    Shults, W.D.

    1993-11-01

    Over the past fifty years, analytical scientist within the DOE complex have had a tremendous impact on the field of analytical chemistry. This paper suggests six ``high impact`` research/development areas that either originated within or were brought to maturity within the DOE laboratories. ``High impact`` means they lead to new subdisciplines or to new ways of doing business.

  6. Darrell Huff and Fifty Years of How to Lie with Statistics

    OpenAIRE

    Steele, J. Michael

    2005-01-01

    Over the last fifty years, How to Lie with Statistics has sold more copies than any other statistical text. This note explores the factors that contributed to its success and provides biographical sketches of its creators: author Darrell Huff and illustrator Irving Geis.

  7. Fifty Years Later: Comments on the Further Development of a Science of Verbal Behavior

    Science.gov (United States)

    Leigland, Sam

    2007-01-01

    Fifty years after the publication of Skinner's "Verbal Behavior", some possibilities for the future of Skinner's "science of verbal behavior" are considered. Specifically, certain areas of development or advancement are examined which might be of special importance to the expansion and influence of the functional analysis of verbal behavior.…

  8. Fifty Ninth Annual Report: United States Department of Labor. Fiscal Year 1971.

    Science.gov (United States)

    Department of Labor, Washington, DC.

    This fifty-ninth annual report of the United States Department of Labor for the fiscal year 1971 contains a 6-page report by the Secretary of Labor, 11 separate Federal Department reports, and a variety of appended tables covering such areas as enrollments and funding for various government programs. Detailing the initiation or improvement of a…

  9. Fifty years of entomological publications in the Revista de Biología Tropical.

    Science.gov (United States)

    Hanson, Paul

    2002-01-01

    Over its fifty year history nearly twenty percent of the papers published in the Revista de Biología Tropical have been about insects and arachnids. In the 1950's papers on arthropods of medical importance were dominant, in the 1960's there was a poliferation of papers on bees, and in more recent years the subjects have become increasingly diverse. In terms of nationality of contributing authors, the journal appears to have become increasingly international in later years.

  10. [Fifty years ago, the double helix gave birth to molecular biology].

    Science.gov (United States)

    Lunardi, J

    2003-01-01

    Fifty years ago, a paper signed by two young scientists, James Watson and Francis Crick, and reporting a model for DNA based on a double helix structure was published in the scientific review Nature in date of april 25, 1953. Although this model of striking simplicity and rare elegance was actually worked out in a few months by the two men, it was the result of quite 100 years of research aimed at the definition of the structure of the genetic material present in living organisms. The double helix was the outcome of a multidisciplinary approach initiated in the mid 19th century by the genetic laws of Gregor Mendel and the discovery of the chemical nature of the desoxyribonucleic acid by Johann Friedrich Miesher. The discovery of the DNA structure had been at the origin of major scientific progress regarding mechanisms that rule the replication and the expression of the genetic information. Theses researches have given birth to a new scientific field, molecular biology, which everyone will see very soon is actually part in a quasi symbiotic manner of all other biological fields dealing with life. The spectacular development of molecular biology during the last fifty years was in great part possible thanks to a concomitant enormous development of the different methods of investigation of the biological molecules and structure. The present rising of biotechnology applications is the direct consequence of the tremendous amount of fundamental knowledge gained during the last few decennia. They open very important and attractive perspectives both on medical or on socio-economic point of views. There is no doubt that the next fifty years will be as fruitful as the last ones.

  11. CASTLE BRAVO: Fifty Years of Legend and Lore. A Guide to Off-Site Radiation Exposures

    Science.gov (United States)

    2013-01-31

    Commander, TG7.1), Bob Campbell (TG7.1 J-6), Carl Lyon (TG7.1 J-3), Garry Higgins (TG7.1 TU-12), and Roger Ray (TG7.1 J-3). Hal Plank (TG7.1 TU-1...scrupulously clear to other laboratory staff members ( Campbell 1985). January 2013 CASTLE BRAVO: Fifty Years of Legend and Lore Introduction 3 Soon...regular mess line for meals and had the same ration as the crew. The meat course was the least popular. The majority of the party asked for more soup

  12. Learning from the Past: A Fifty-year Perspective on Pakistan's Development

    OpenAIRE

    Pervez Hasan

    1997-01-01

    In some ways, Pakistan’s economic growth since 1947 has been remarkable. The country’s economic viability was considered, in some quarters,1 in serious doubt at its emergence, but it has managed, despite a quadrupling of the population, to bring about significant improvement in the average living standards. Per capita GNP growth, on average around 2 percent per annum over a long stretch of nearly fifty years, has been the best among countries of the subcontinent. This growth has meant an incr...

  13. The continuous time random walk, still trendy: fifty-year history, state of art and outlook

    Science.gov (United States)

    Kutner, Ryszard; Masoliver, Jaume

    2017-03-01

    In this article we demonstrate the very inspiring role of the continuous-time random walk (CTRW) formalism, the numerous modifications permitted by its flexibility, its various applications, and the promising perspectives in the various fields of knowledge. A short review of significant achievements and possibilities is given. However, this review is still far from completeness. We focused on a pivotal role of CTRWs mainly in anomalous stochastic processes discovered in physics and beyond. This article plays the role of an extended announcement of the Eur. Phys. J. B Special Issue [http://epjb.epj.org/open-calls-for-papers/123-epj-b/1090-ctrw-50-years-on">http://epjb.epj.org/open-calls-for-papers/123-epj-b/1090-ctrw-50-years-on] containing articles which show incredible possibilities of the CTRWs. Contribution to the Topical Issue "Continuous Time Random Walk Still Trendy: Fifty-year History, Current State and Outlook", edited by Ryszard Kutner and Jaume Masoliver.

  14. Fifty Years Remembered: The First 50 Years of the Tulsa District, U.S. Army Corps of Engineers

    Science.gov (United States)

    1989-07-01

    District Engineer! Col. Frank Patete Project Manager! Beverly Leland Author! Ann Patton Managing Editor! Larry Silvey Production Manager! Michael Shelton...youngsters and fishermen, Pat Mayse raft riders, Keystone Triathe/on swimmers , Broken Bow hikers, and Keystone campers. SECTION 1: FIFTY YEARS OF...representative of construction contractor Hensel Phelps sign the contract for repairs to begin. REBUILDING TINKER’S 3001 It was the largest and most

  15. Fifty Years of Progress, 1937-1987 [Lawrence Berkeley Laboratory (LBL, LBNL)

    Science.gov (United States)

    Budinger, T. F. (ed.)

    1987-01-01

    This booklet was prepared for the 50th anniversary of medical and biological research at the Donner Laboratory and the Lawrence Berkeley Laboratory of the University of California. The intent is to present historical facts and to highlight important facets of fifty years of accomplishments in medical and biological sciences. A list of selected scientific publications from 1937 to 1960 is included to demonstrate the character and lasting importance of early pioneering work. The organizational concept is to show the research themes starting with the history, then discoveries of medically important radionuclides, then the use of accelerated charged particles in therapy, next human physiology studies then sequentially studies of biology from tissues to macromolecules; and finally studies of the genetic code.

  16. Advances in Cotton Breeding for Resistance to Fusarium and Verticillium Wilt in the Last Fifty Years in China

    Institute of Scientific and Technical Information of China (English)

    JIAN Gui-liang; MA Cun; ZHENG Chuan-lin; ZOU Ya-fei

    2003-01-01

    This review summarizes the main advances in cotton breeding for resistance to fusarium andverticillium wilt in the last fifty years in China. The topics discussed include main achievements, experiences,problems and countermeasures for solving.

  17. FOREWORD: Fifty years of atomic time-keeping: 1955 to 2005

    Science.gov (United States)

    Quinn, Terry

    2005-06-01

    The year 2005 is the centenary of Einstein's four famous papers that were published in 1905. This anniversary is being widely celebrated all over the world and, indeed, 2005 has been dubbed World Year of Physics. The year 2005, however, also marks the fiftieth anniversary of the first operation of Essen and Parry's caesium beam atomic frequency standard at the NPL in May 1955. While Einstein's papers signalled a revolution in physics and in our understanding of the natural world, the first atomic clock signalled a revolution in time-keeping that has become, among other things, one of the most powerful tools in pushing back the frontiers of Einstein's theories of special and general relativity. The atomic clock has also had consequences for navigation comparable to those brought about by Harrison's mechanical clocks almost exactly two hundred years before. Harrison's H3 was completed in 1757 and H4 in 1759. The atomic clock, and the creation of an atomic time scale that quickly followed, led ten years later to the adoption of an atomic definition for the SI second in Resolution 1 of the 13th General Conference on Weights and Measures, 1967/68. This marked the end of time-keeping based on the movements of the heavenly bodies that had beaten the rhythm of the days and the seasons since the dawn of human civilization. Fifty years on is a good occasion to look back, to look forward and at the same time to examine where we are today, in terms of measuring time. While we still arrange for our atomic clocks to show noon when the sun is overhead on the Greenwich meridian, everything else has changed in the fifty years since 1955. In this special issue of Metrologia the reader will find articles on the development of the atomic clock, its theory and practice, how the first atomic time scale was devised and formally introduced and how we maintain atomic time today, as well as articles looking forward to even more accurate clocks and time scales. Included also are articles on

  18. Fifty years of co-evolution and beyond: integrating co-evolution from molecules to species.

    Science.gov (United States)

    Carmona, Diego; Fitzpatrick, Connor R; Johnson, Marc T J

    2015-11-01

    Fifty years after Ehrlich and Raven's seminal paper, the idea of co-evolution continues to grow as a key concept in our understanding of organic evolution. This concept has not only provided a compelling synthesis between evolutionary biology and community ecology, but has also inspired research that extends beyond its original scope. In this article, we identify unresolved questions about the co-evolutionary process and advocate for the integration of co-evolutionary research from molecular to interspecific interactions. We address two basic questions: (i) What is co-evolution and how common is it? (ii) What is the unit of co-evolution? Both questions aim to explore the heart of the co-evolutionary process. Despite the claim that co-evolution is ubiquitous, we argue that there is in fact little evidence to support the view that reciprocal natural selection and coadaptation are common in nature. We also challenge the traditional view that co-evolution only occurs between traits of interacting species. Co-evolution has the potential to explain evolutionary processes and patterns that result from intra- and intermolecular biochemical interactions within cells, intergenomic interactions (e.g. nuclear-cytoplasmic) within species, as well as intergenomic interactions mediated by phenotypic traits between species. Research that bridges across these levels of organization will help to advance our understanding of the importance of the co-evolutionary processes in shaping the diversity of life on Earth. © 2015 John Wiley & Sons Ltd.

  19. From pharmaceutical standardizing to clinical research: 20 years of experience with fifty-millesimal potencies

    Directory of Open Access Journals (Sweden)

    Wania Papile Galhardi

    2009-12-01

    Full Text Available Background: 20 years ago we began to standardize the procedures of preparation and use of fifty-millesimal dilutions (LM or Q according to indications in the 6th edition of Hahnemann’s Organon. Aim: to describe the main stages in standardization as well as our teaching and research experience on Organon 6th edition. Results: with the use of standardized LM dilutions we observed a lower incidence of homeopathic aggravation than with our earlier experience with non standardized preparations. Organon.modus, a clinical-pharmaceutical protocol derived from the standardization was adequate for the teaching of homeopathy at Faculty of Medicine of Jundiai (São Paulo, the first Brazilian medical school with a graduate course on homeopathy. A randomized double-blind trial comparing individualized homeopathic medicines prescribed in LM dilutions and fluoxetine showed the former not be inferior to the latter in the treatment of moderate-to-severe depression. Conclusion: protocol Organon.modus showed to be adequate to graduate-level teaching of homeopathy and efficient in a controlled clinical trials, favoring its use as common denominator between the art of healing and medical science.

  20. Fifty years of the integrated control concept: moving the model and implementation forward in Arizona.

    Science.gov (United States)

    Naranjo, Steven E; Ellsworth, Peter C

    2009-12-01

    Fifty years ago, Stern, Smith, van den Bosch and Hagen outlined a simple but sophisticated idea of pest control predicated on the complementary action of chemical and biological control. This integrated control concept has since been a driving force and conceptual foundation for all integrated pest management (IPM) programs. The four basic elements include thresholds for determining the need for control, sampling to determine critical densities, understanding and conserving the biological control capacity in the system and the use of selective insecticides or selective application methods, when needed, to augment biological control. Here we detail the development, evolution, validation and implementation of an integrated control (IC) program for whitefly, Bemisia tabaci (Genn.), in the Arizona cotton system that provides a rare example of the vision of Stern and his colleagues. Economic thresholds derived from research-based economic injury levels were developed and integrated with rapid and accurate sampling plans into validated decision tools widely adopted by consultants and growers. Extensive research that measured the interplay among pest population dynamics, biological control by indigenous natural enemies and selective insecticides using community ordination methods, predator:prey ratios, predator exclusion and demography validated the critical complementary roles played by chemical and biological control. The term 'bioresidual' was coined to describe the extended environmental resistance from biological control and other forces possible when selective insecticides are deployed. The tangible benefits have been a 70% reduction in foliar insecticides, a >$200 million saving in control costs and yield, along with enhanced utilization of ecosystem services over the last 14 years.

  1. Emerging frontiers of pharmacy education in Saudi Arabia: The metamorphosis in the last fifty years

    Science.gov (United States)

    Asiri, Yousif A.

    2010-01-01

    The trends in the quality of biomedical education in pharmacy schools have witnessed significant changes in the 21st century. With the advent of continuous revision and standardization processes of medical curricula throughout the world, the focus has been on imparting quality education. This pedagogic paradigm has shifted to pharmacy schools. In Saudi Arabia, the concept of “medical and pharmacy education” is relatively new as mainstream pharmacy curriculum and universities were established only half a century ago. This period has seen major changes in the dimension of “pharmacy education” to keep pace with the education systems in the United States and Europe. As our knowledge and perceptions about pharmaceuticals change with time, this motivates educators to search for better teaching alternatives to the ever increasing number of enthusiastic and budding pharmacists. Recently, the academic system in Saudi Arabian Pharmacy has adopted a more clinically-oriented Pharm. D. curriculum. This paper deals with the major changes from the inception of a small pharmacy faculty in 1959, the College of Pharmacy at the King Saud University, Riyadh, to the model of progress and a prototype of pharmacy colleges in Saudi Arabia. The fifty year chronological array can be regarded as an epitome of progress in pharmacy education in Saudi Arabia from its traditional curriculum to the modern day Pharm. D. curriculum with a high population growth and expanding health care sector, the demand for qualified pharmacists is growing and is projected to grow considerably in the future. The number of pharmacy graduates is increasing each year by many folds and to meet the needs the system lays stress upon a constant revising and updating of the current curriculum from a global perspective. PMID:23960737

  2. Reflections on fifty years of publications on the history of general biology and special embryology.

    Science.gov (United States)

    Oppenheimer, J M

    1975-12-01

    The publications of fifty years (1925-1974) of the histroy of biology and embryology are surveyed. In America, the earliest background for work during this period was provided by the collectors, mainly physicians, of books into extensive private libraries. The collectors, for instance Osler, Cushing, and Fulton in this country and Geoffrey Keynes abroad, became expert technical bibliographers during the early part of the half-century under consideration. High standards for medical, thus biological history, insofar as these fields overlap, were also set earlier by Sudhoff's Institut für Geschichte der Medizin in Leipzig, and American historical studies benefited when Sigerist came from Leipzig to Baltimore in the early 1930's. Textbooks of medical history are omitted from discussion here, but a number of more or less general histories of biology published within the specified period are briefly evaluated. The discussion next turns to histories of embryology, general and special. Recent monographs on the classical embryologists, Wolff and von Baer, are enumerated, as are a number of biographies and autobiographies of important embryologists published here or abroad during our half-century. Then general histories of embryology are discussed, and finally some specialized ones. Needham, Roger, and Adelmann are singled out as the most important contributors to the history of embryology, in the West, during the period covered. Few of the contributors to the history of biology and medicine during the years of 1925 through 1974 were trained as historians while students. It is concluded that the History of Science Society has performed an important contribution in professionalizing the history of biology and embryology, but it is pointed out that a great new challenge faces it in the necessity to counteract anti-historical and anti-intellectual moods and movements of today.

  3. Through the Looking Glass: Adult Education through the Lens of the Australian Journal of Adult Learning over Fifty Years

    Science.gov (United States)

    Harris, Roger; Morrison, Anne

    2011-01-01

    In this paper we review fifty years of articles published in Australian Journal of Adult Learning in its various iterations. We examine the different roles of the journal: to illuminate the history and trends of adult education authors; to be the flagship of the adult education profession in Australia; to reflect on significant national events;…

  4. A Fifty-Year Love Affair with Organic Chemistry (by William S. Johnson)

    Science.gov (United States)

    Kauffman, Reviewed By George B.; Kauffman, Laurie M.

    1999-12-01

    This latest volume is the 20th in Jeff Seeman's projected 22-volume series of autobiographies of 20th-century organic chemists that began publication in 1990 (Kauffman, G. B. J. Chem. Educ. 1991, 68, A21). Unfortunately, Johnson did not live to see this volume in print. Ted Bartlett and Ray Conrow reviewed the final manuscript, galleys, and page proofs; and Ted Bartlett, Paul Bartlett, John D. Roberts, and Gilbert Stork contributed an epilogue that complements Johnson's own words, adds a warm, personal final touch that he was unable to provide, and incorporates his final research into the volume. Born in New Rochelle, New York, on February 24, 1913, William Summer Johnson attended Amherst College with the aid of a scholarship and various odd jobs such as tending furnace, washing dishes, and playing saxophone in dance bands (he seriously considered becoming a professional musician). Here he became enamored with organic chemistry, which he taught as an instructor for a year after his graduation magna cum laude in 1936. He then worked with a fellowship under Louis Fieser, who sparked his interest in steroids, at Harvard University, from which he received his M.A. (1938) and Ph.D. (1940) degrees. In 1940 Johnson joined the faculty at the University of Wisconsin, where he rose through the ranks, eventually becoming Homer Adkins Professor of Chemistry (1954-60). He began the total synthesis of steroids, the main subject of his life's work, "which soon proved to be the hottest synthetic target of the time". In 1960 he accepted an invitation to become head of and to upgrade the Stanford University Chemistry Department. With faculty recruiting as his primary concern, he was able to add Carl Djerassi, Paul J. Flory, Harden M. McConnell, Henry Taube, and Eugene E. van Tamelen to the department, resulting in its spectacular rise from 15th to 5th place in the nation. He remained at Stanford for the rest of his career, serving as department head for nine years. He died at the

  5. Fifty Years of "Comparative Education Review" Bibliographies: Reflections on the Field

    Science.gov (United States)

    Raby, Rosalind Latiner

    2007-01-01

    For the past three years, the "Comparative Education Review" ("CER") has published annual bibliographic essays reflecting the changes in the field over the previous year. This year, to mark the 50th anniversary of the Comparative and International Education Society (CIES), the author analyzed "CER" bibliographies since 1959, in addition to…

  6. Fifty years of language maintenance and language dominance in bilingual Hispanic immigrants.

    Science.gov (United States)

    Bahrick, H P; Hall, L K; Goggin, J P; Bahrick, L E; Berger, S A

    1994-09-01

    Spanish language tests of 801 Cuban and Mexican immigrants showed no evidence of language loss during 50 years of U.S. residence; a few years after immigration, their English vocabulary approximated that of English monolinguals. The critical-age hypothesis was not supported for the acquisition of English vocabulary when English schooling and language usage were controlled by multiple regression. Most Ss continued to speak about as much Spanish as English; but read, wrote, and heard (on television and radio) far more English than Spanish. Under these conditions, Ss maintained Spanish dominance on tests of vocabulary recognition, lexical decision, and oral comprehension. Dominance was task specific and shifted to English on a category generation task about 12 years after immigration. No evidence of bilingual language interference was found; this is attributed to the strong Spanish foundation of the participants.

  7. Fifty-Year Flood-Inundation Maps for Santa Rosa de Aguan, Honduras

    Science.gov (United States)

    Mastin, Mark C.; Olsen, T.D.

    2002-01-01

    After the devastating floods caused by Hurricane Mitch in 1998, maps of the areas and depths of the 50-year-flood inundation at 15 municipalities in Honduras were prepared as a tool for agencies involved in reconstruction and planning. This report, which is one in a series of 15, presents maps of areas in the coastal municipality of Santa Rosa de Aguan that are prone to oceanic storm-surge flooding and wave action. The 50-year flood on the Rio Aguan (4,270 cubic meters per second), would inundate most of the area surveyed for this municipality and beyond. Therefore a detailed numerical hydraulic model was not developed for this municipality as it was for the others. The 50-year storm surge would likely produce higher water levels than the 50-year flood on the river during normal astronomical tides. The elevation of the 50-year storm surge was estimated to be 4.35 meters above normal sea level, based on hurricane probabilities and published storm-surge elevations associated with various hurricane categories. Flood-inundation maps, including areas of wave-action hazard and a color-shaded elevation map, were created from the available data and the estimated 50-year storm tide. Geographic Information System (GIS) coverages of the hazard areas are available on a computer in the municipality of Santa Rosa de Aguan as part of the Municipal GIS project and on the Internet at the Flood Hazard Mapping Data Web page (http://mitchnts1.cr.usgs.gov/projects/floodhazard.html). These coverages allow users to view the maps in much more detail than is possible using the maps in this report.

  8. Fifty-year follow-up and Strampelli anterior chamber intraocular lens.

    Science.gov (United States)

    Oakley, Carmen L; Nigro, Matthew A; Vote, Brendan J

    2015-01-01

    The Strampelli anterior chamber intraocular lens was created in 1953, and was primarily used to treat myopia and aphakia. Due to the positioning of the lens, it was associated with a number of complications, and was later modified to decrease the rate of significant complications, including endothelial cell loss. This paper describes a 62-year-old man, who has had a Strampelli intraocular lens (IOL) in situ for 52 years, with relatively few complications. The case provides a framework for reflection on the significant advances in the development of IOLs since the Strampelli era. The Strampelli anterior chamber intraocular lens was created in 1953, and was primarily used to treat myopia and aphakia. Due to the positioning of the lens, it was associated with a number of complications, and was later modified to decrease the rate of significant complications, including endothelial cell loss. This paper describes a 62-year-old man, who has had a Strampelli intraocular lens (IOL) in situ for 52 years, with relatively few complications. The case provides a framework for reflection on the significant advances in the development of IOLs since the Strampelli era.

  9. Fifty years of oil exploration in Nigeria: the paradox of plenty ...

    African Journals Online (AJOL)

    Yet over many years, it has been observed that nations rich in oil, gas, or mineral ... with rich endowments of natural resources [oil as in the case of Nigeria] often ... like this had given rise to other contemporary oil nations overtaking Nigeria.

  10. Visualizing DNA domains and sequences by microscopy: a fifty-year history of molecular cytogenetics.

    NARCIS (Netherlands)

    Jong, de J.H.S.G.M.

    2003-01-01

    This short review presents a historical perspective of chromosome research during the last 50 years. It shows how molecular knowledge and technology of DNA entered cytogenetics step by step making it now daily practice in almost every modem chromosome lab. A crucial milestone in these decades has be

  11. Fifty-Year Trends in the Chemical Industry: What Do They Mean for Chemical Education?

    Science.gov (United States)

    Tolman, Chadwick A.; Parshall, George W.

    1999-01-01

    Describes major changes that have occurred in the chemical industry over the last 50 years including trends in the development of products and processes, changes in chemical manufacturing, the globalization of business, and modifications of research laboratory practices. Discusses implications for chemistry education and predictions for future…

  12. Fifty-odd years of inter-group contact: from hypothesis to integrated theory.

    Science.gov (United States)

    Hewstone, Miles; Swart, Hermann

    2011-09-01

    We review 50-odd years of research on Allport's (1954)'contact hypothesis', to assess progress, problems, and prospects. We chart the progress that has been made in understanding two distinct forms of contact: direct and indirect. We highlight the progress made in understanding the effects of each type of contact, as well as both moderating and mediating factors, and emphasize the multiple impacts of direct contact, especially. We then consider some of the main critiques of inter-group contact, focusing on empirical issues and whether contact impedes social change, and provide a research agenda for the coming years. We conclude that this body of work no longer merits the modest title of 'hypothesis', but fully deserves acknowledgement as an integrated and influential theory.

  13. Fifty years with the Hamilton scales for anxiety and depression. A tribute to Max Hamilton

    DEFF Research Database (Denmark)

    Bech, P

    2009-01-01

    From the moment Max Hamilton started his psychiatric education, he considered psychometrics to be a scientific discipline on a par with biochemistry or pharmacology in clinical research. His clinimetric skills were in operation in the 1950s when randomised clinical trials were established...... as the method for the evaluation of the clinical effects of psychotropic drugs. Inspired by Eysenck, Hamilton took the long route around factor analysis in order to qualify his scales for anxiety (HAM-A) and depression (HAM-D) as scientific tools. From the moment when, 50 years ago, Hamilton published his first...... placebo-controlled trial with an experimental anti-anxiety drug, he realized the dialectic problem in using the total score on HAM-A as a sufficient statistic for the measurement of outcome. This dialectic problem has been investigated for more than 50 years with different types of factor analyses without...

  14. A new experimental proposal for {sup 235}U PFNS to answer a fifty years old question

    Energy Technology Data Exchange (ETDEWEB)

    Kornilov, N.; Massey, T.; Grimes, S.; Voinov, A. [Dept. of Physics and Astronomy, Ohio Univ., Athens, OH 45701 (United States)

    2011-07-01

    The Prompt Fission Neutron Spectrum (PFNS) from {sup 235}U(n,f) is very important for various nuclear applications. It has been investigated in different experiments. In spite of {approx}50 years of experimental efforts, a continuing conflict exists at thermal neutron energy. Microscopic experimental PFNS cannot describe macroscopic data. In this report we discuss the current status of this problem and suggest a new experiment, which could possibly resolve this problem. (authors)

  15. Fifty years of studying the Medvezhiy Glacier (West Pamirs) by the Institute of Geography, RAS

    OpenAIRE

    G. B. Osipova

    2015-01-01

    Overview of researches conducted over 50 years (1963–2012) by Institute of Geography RAS on the surging glacier Medvezhiy, the West Pamirs is given. Ground investigations (changes of its surface altitude, ice movement velocity, ablation, ice thickness, temperature and others) made after surge 1963 allowed finding the basic features of this glacier regime and calculating the mass balance of its surging part for the whole cycle from the recovery phase up to a surge. Using the results a quality ...

  16. The 1953 Stanley L. Miller Experiment: Fifty Years of Prebiotic Organic Chemistry

    Science.gov (United States)

    Lazcano, Antonio; Bada, Jeffrey L.

    2003-01-01

    The field of prebiotic chemistry effectively began with a publication in Science 50 years ago by Stanley L. Miller on the spark discharge synthesis of amino acids and other compounds using a mixture of reduced gases that were thought to represent the components of the atmosphere on the primitive Earth. On the anniversary of this landmark publication, we provide here an accounting of the events leading to the publication of the paper. We also discuss the historical aspects that lead up to the landmark Miller experiment.

  17. Fifty Years of Sino-Norwegian Cooperation——An Interview with Norwegian Ambassador

    Institute of Scientific and Technical Information of China (English)

    QiuJianghong

    2004-01-01

    Geographical distance has not hindered friendly relations, ongoing for more than two centuries, between China and Norway. Norway recognized the People's Republic of China on January 7, 1950 and diplomatic relations were established on October 5, 1954. In 1955, the two countries began to exchange ambassadors. Since then their political, economic and cultural cooperation has steadily advanced. The year 2004 marks the 50th anniversary of establishment of Sino-Norwegian diplomatic relations. In honor of the occasion, China Today spoke with Norwegian Ambassador Tor Chr. Hildan on bilateral trade and economic cooperation.

  18. A Fifty-Year Sustainability Assessment of Italian Agro-Forest Districts

    Directory of Open Access Journals (Sweden)

    Fabio Recanatesi

    2015-12-01

    Full Text Available As cropland management and land use shifted towards more intensive practices, global land degradation increased drastically. Understanding relationships between ecological and socioeconomic drivers of soil and landscape degradation within these landscapes in economically dynamic contexts such as the Mediterranean region, requires multi-target and multi-scalar approaches covering long-term periods. This study provides an original approach for identifying desertification risk drivers and sustainable land management strategies within Italian agro-forest districts. An Environmental Sensitivity Area (ESA approach, based on four thematic indicators (climate, soil, vegetation and land-use and a composite index of desertification risk (ESAI, was used to evaluate changes in soil vulnerability and landscape degradation between the years 1960 and 2010. A multivariate model was developed to identify the most relevant drivers causing changes in land susceptibility at the district scale. Larger districts, and those with a higher proportion of their total surface area classified as agro-forest, had a significantly lower increase in land susceptibility to degradation during the 50 years when compared with the remaining districts. We conclude that preserving economic viability and ecological connectivity of traditional, extensive agricultural systems is a key measure to mitigate the desertification risk in the Mediterranean region.

  19. Fifty years of studying the Medvezhiy Glacier (West Pamirs by the Institute of Geography, RAS

    Directory of Open Access Journals (Sweden)

    G. B. Osipova

    2015-01-01

    Full Text Available Overview of researches conducted over 50 years (1963–2012 by Institute of Geography RAS on the surging glacier Medvezhiy, the West Pamirs is given. Ground investigations (changes of its surface altitude, ice movement velocity, ablation, ice thickness, temperature and others made after surge 1963 allowed finding the basic features of this glacier regime and calculating the mass balance of its surging part for the whole cycle from the recovery phase up to a surge. Using the results a quality model for prediction of rapid motions of surging glaciers had been developed. Forecast of the next surge of the Medvezhiy Glacier made for 1973 on the basis of this model had been justified. As a result of the aerial and topographic monitoring (1989–1991 the glacier surge was quantitatively followed for the first time over its whole cycle, i.e. from a surge up to a next stage of its recovery. Results of our researches allowed formulating the foundations of the space monitoring of surging glaciers. In 2001 and 2011 surges of the glacier were detected and traced using the satellite imagery (MIR, ISS. In total for 50 years, five surges of this glacier and two full cycles of its life were investigated by various methods in different details.

  20. Fifty Years of Clinical Application of Newcastle Disease Virus: Time to Celebrate!

    Directory of Open Access Journals (Sweden)

    Volker Schirrmacher

    2016-07-01

    Full Text Available This review provides an overview of 50 years of basic and clinical research on an oncolytic avian virus, Newcastle Disease Virus (NDV, which has particular anti-neoplastic and immune stimulatory properties. Of special interest is the fact that this biological agent induces immunogenic cell death and systemic anti-tumor immunity. Furthermore, localized oncolytic virotherapy with NDV was shown to overcome systemic tumor resistance to immune checkpoint blockade immunotherapy. Clinical experience attests to low side effects and a high safety profile. This is due among others to the strong virus-induced type I interferon response. Other viral characteristics are lack of interaction with host cell DNA, lack of genetic recombination and independence of virus replication from cell proliferation. In this millennium, new recombinant strains of viruses are being produced with improved therapeutic properties. Clinical applications include single case observations, case series studies and Phase I to III studies.

  1. [Fifty years of psychiatry at the interface between psyche and soma: a SWOT analysis].

    Science.gov (United States)

    van Houdenhove, B; Luyten, P

    2008-01-01

    During the past 50 years the border area between psychiatry and somatic medicine has undergone remarkable changes. Theories have become better-founded, both psychologically and neurobiologically, research has become more sophisticated, and liaison-psychiatrists and health psychiatrist/behavioural medicine psychologists have played an increasingly active role in this domain. At the beginning of the 21st century modern psychosomatic medicine is facing new challenges; these include how to create a workable diagnostic classification system, how to instruct and educate both health professionals and lay-persons to an adequate level, how to utilize innovative research paradigms without having recourse to reductionism and how to implement in medical practice treatments that are geared to the needs of the individual patient.

  2. Invertebrate learning and memory: Fifty years of olfactory conditioning of the proboscis extension response in honeybees.

    Science.gov (United States)

    Giurfa, Martin; Sandoz, Jean-Christophe

    2012-02-01

    The honeybee Apis mellifera has emerged as a robust and influential model for the study of classical conditioning, thanks to the existence of a powerful Pavlovian conditioning protocol, the olfactory conditioning of the proboscis extension response (PER). In 2011, the olfactory PER conditioning protocol celebrates 50 years since it was first introduced by Kimihisa Takeda in 1961. Here, we review its origins, developments, and perspectives in order to define future research avenues and necessary methodological and conceptual evolutions. We show that olfactory PER conditioning has become a versatile tool for the study of questions in extremely diverse fields in addition to the study of learning and memory and that it has allowed behavioral characterizations, not only of honeybees, but also of other insect species, for which the protocol was adapted. We celebrate, therefore, Takeda's original work and prompt colleagues to conceive and establish further robust behavioral tools for an accurate characterization of insect learning and memory at multiple levels of analysis.

  3. World meat consumption patterns: An overview of the last fifty years (1961-2011).

    Science.gov (United States)

    Sans, P; Combris, P

    2015-11-01

    Driven by economic development and urbanisation, protein consumption has surged worldwide over the last 50years, rising from 61g per person per day in 1961 to 80g per person per day in 2011 [Corrected]. This contribution analyses the apparent convergence of dietary models worldwide with respect to the proportion of ABP and especially meat in intake. By using FAO data for 183 countries over the period 1961-2011, the authors show the connection between annual per capita GDP and the level of ABP (R2=0.62) and meat consumption (R2=0.62). They emphasise the surge in ABP intake in emerging countries (China, Brazil) which has partly replaced plant protein. However, for similar degrees of economic development, the composition of ABPs and the position of meat within this category vary significantly among countries, suggesting that historical, geographical, cultural and religious factors may be involved.

  4. Cognitive function fifty-six years after surgical treatment of temporal lobe epilepsy: A case study

    Directory of Open Access Journals (Sweden)

    Sarah Jane Banks

    2014-01-01

    Our investigation at 56 postoperative years focused on cognitive skills, with some emphasis on learning and memory; a clinical examination was also performed, and the anatomical extent of the resection was determined on 3-Tesla magnetic resonance imaging. Four age- and IQ-appropriate women were tested as healthy control subjects. The patient showed material-specific impairments in language and verbal memory compared with the control subjects and also compared with her own earlier performance, but her performance on other cognitive tasks did not differ from that of the control subjects. Thus, her specific deficits had worsened over time, and she was also impaired compared with healthy individuals of her age, but her deficits remained confined to the verbal sphere, consistent with her temporal lobe seizure focus and surgery.

  5. Fifty years of computer analysis in chest imaging: rule-based, machine learning, deep learning.

    Science.gov (United States)

    van Ginneken, Bram

    2017-03-01

    Half a century ago, the term "computer-aided diagnosis" (CAD) was introduced in the scientific literature. Pulmonary imaging, with chest radiography and computed tomography, has always been one of the focus areas in this field. In this study, I describe how machine learning became the dominant technology for tackling CAD in the lungs, generally producing better results than do classical rule-based approaches, and how the field is now rapidly changing: in the last few years, we have seen how even better results can be obtained with deep learning. The key differences among rule-based processing, machine learning, and deep learning are summarized and illustrated for various applications of CAD in the chest.

  6. Legend and legacy: Fifty years of defense production at the Hanford Site

    Energy Technology Data Exchange (ETDEWEB)

    Gerber, M.S.

    1992-09-01

    Today, the Hanford Site is engaged in the largest waste cleanup effort ever undertaken in human history. That in itself makes the endeavor historic and unique. The Hanford Site has been designated the ``flagship`` of Department of Energy (DOE) waste remediation endeavors. And, just as the wartime Hanford Project remains unmatched in history, no counterpart exists for the current waste cleanup enterprise. This report provides a summary of the extensive historical record, however, which does give a partial road map. The science of environmental monitoring pioneered at the Hanford Site, and records of this type are the most complete of any in the world, from private companies or public agencies, for the early years of Site operations. The Hanford Site was unique for establishing a detailed, scientific, and multi-faceted environmental monitoring program.

  7. Fifty years of immunisation in Australia (1964-2014): the increasing opportunity to prevent diseases.

    Science.gov (United States)

    Royle, Jenny; Lambert, Stephen B

    2015-01-01

    Medicine has seen dramatic changes in the last 50 years, and vaccinology is no different. Australia has made a significant contribution to world knowledge on vaccine-preventable diseases. Certain deadly diseases have disappeared or become rare in Australia following successful introduction of vaccines. As diseases become rarer, public knowledge about the diseases and their serious consequences has decreased, and concerns about potential vaccine side effects have increased. To maintain confidence in immunisations, sharing of detailed information about the vaccines and the diseases we are trying to prevent is integral to the continued success of our public health programme. Modern quality immunisation programmes need to communicate complex information to immunisation providers and also to the general community. Improving immunisation coverage rates and eliminating the gap in coverage and timeliness between Aboriginal and Torres Strait Islander peoples and non-Indigenous people has become a high priority.

  8. Hydro-Quebec and Quebec society: fifty years of shared history

    Energy Technology Data Exchange (ETDEWEB)

    Linteau, P. A. [Quebec Univ., Montreal, PQ (Canada)

    1993-12-31

    An historical overview of Hydro-Quebec, the giant electric utility, and its influence on Quebec society was provided on the occasion of the Corporation`s fiftieth anniversary. Its role in Quebec`s economic nationalism, especially since the 1960s, and its role and achievements in research through IREQ, the Quebec electricity research institute, were explained. The challenges facing the Corporation in the years to come in terms of meeting growing demands for power, in meeting expectations in terms of their role as the engine of Quebec`s economic well-being, environmental concerns, and no less importantly, dealing with native peoples` opposition to further development of lands they claim as their own, were briefly discussed. 6 refs., photos.

  9. One hundred and fifty years of sprint and distance running - Past trends and future prospects.

    Science.gov (United States)

    Weiss, Martin; Newman, Alexandra; Whitmore, Ceri; Weiss, Stephan

    2016-01-01

    Sprint and distance running have experienced remarkable performance improvements over the past century. Attempts to forecast running performances share an almost similarly long history but have relied so far on relatively short data series. Here, we compile a comprehensive set of season-best performances for eight Olympically contested running events. With this data set, we conduct (1) an exponential time series analysis and (2) a power-law experience curve analysis to quantify the rate of past performance improvements and to forecast future performances until the year 2100. We find that the sprint and distance running performances of women and men improve exponentially with time and converge at yearly rates of 4% ± 3% and 2% ± 2%, respectively, towards their asymptotic limits. Running performances can also be modelled with the experience curve approach, yielding learning rates of 3% ± 1% and 6% ± 2% for the women's and men's events, respectively. Long-term trends suggest that: (1) women will continue to run 10-20% slower than men, (2) 9.50 s over 100 m dash may only be broken at the end of this century and (3) several middle- and long-distance records may be broken within the next two to three decades. The prospects of witnessing a sub-2 hour marathon before 2100 remain inconclusive. Our results should be interpreted cautiously as forecasting human behaviour is intrinsically uncertain. The future season-best sprint and distance running performances will continue to scatter around the trends identified here and may yield unexpected improvements of standing world records.

  10. Fifty years dynamics of Russian forests: Impacts on the earth system

    Science.gov (United States)

    Shvidenko, Anatoly; Schepaschenko, Dmitry; Kraxner, Florian

    2015-04-01

    The paper presents a succinct history of Russian forests during the time period of 1960-2010 and reanalysis of their impacts on global carbon and nitrogen cycles. We present dynamics of land cover change (including major categories of forest land) and biometric characteristics of forests (species composition, age structure, growing stock volume etc.) based on reconciling all relevant information (data of forest and land inventories, official forest management statistics, multi-sensor remote sensing products, data of forest pathological monitoring etc.). Completeness and reliability of background information was different during the period of the study. Forest inventory data and official statistics were partially modified based on relevant auxiliary information and used for 1960-2000. The analysis for 2001-2010 was provided with a crucial use of multi-sensor remote sensing data. For this last period a hybrid forest mask was developed at resolution of 230m by integration of 8 remote sensing products and using geographical weighted regression and data of crowdsourcing. During the considered 50 years forested areas of Russia substantially increased by middle of 1990s and slightly declined (at about 5%) after. Indicators needed for assessment of carbon and nitrogen cycles of forest ecosystems were defined for the entire period (aggregated estimates by decades for 1960-2000 and yearly for 2001-2010) based on unified methodology with some peculiarities following from availability of information. Major results were obtained by landscape-ecosystem method that uses as comprehensive as possible empirical and semi-empirical information on ecosystems and landscapes in form of an Integrated Land Information System and complimentary combines pool- and flux-based methods. We discuss and quantify major drivers of forest cover change (socio-economic, environmental and climatic) including forest management (harvest, reforestation and afforestation), impacts of seasonal weather on

  11. Impacts of Climatic Change on River Runoff in Northern Xinjiang of China over Last Fifty Years

    Institute of Scientific and Technical Information of China (English)

    YANG Yuhui; CHEN Yaning; LI Weihong; WANG Minzhong; SUN Guili

    2010-01-01

    The characteristics of climatic change and river runoff, as well as the response of river runoff to climatic change in the northern Xinjiang are analyzed on the basis of the hydrological and meteorological data over the last 50 years by the methods of Mann-Kendall nonparametric test and the nonlinear regression model. The results show that: 1) The temperature and the precipitation increased significantly in the whole northern Xinjiang, but the precipitation displayed no obvious change, or even a decreasing trend in the northern mountainous area of the northern Xinjiang. 2) River runoff varied in different regions in the northern Xinjiang. It significantly increased in the northern slope of the Tianshan Mountains and the north of the northern Xinjiang (p=0.05), while slightly increased in the west of the northern Xinjiang. 3) North Atlantic Oscillation (NAO) affects river runoff by influencing temperature and precipita-tion. The NAO and precipitation had apparent significant correlations with the river runoff, but the temperature did not in the northern Xinjiang. Since the mid-1990s river runoff increase was mainly caused by the increasing temperature in the northern slope of the Tianshan Mountains and the north of the northern Xinjiang. Increased precipitation resulted in increased river runoff in the west of the northern Xinjiang.

  12. The Sertoli cell: one hundred fifty years of beauty and plasticity.

    Science.gov (United States)

    França, L R; Hess, R A; Dufour, J M; Hofmann, M C; Griswold, M D

    2016-03-01

    It has been one and a half centuries since Enrico Sertoli published the seminal discovery of the testicular 'nurse cell', not only a key cell in the testis, but indeed one of the most amazing cells in the vertebrate body. In this review, we begin by examining the three phases of morphological research that have occurred in the study of Sertoli cells, because microscopic anatomy was essentially the only scientific discipline available for about the first 75 years after the discovery. Biochemistry and molecular biology then changed all of biological sciences, including our understanding of the functions of Sertoli cells. Immunology and stem cell biology were not even topics of science in 1865, but they have now become major issues in our appreciation of Sertoli cell's role in spermatogenesis. We end with the universal importance and plasticity of function by comparing Sertoli cells in fish, amphibians, and mammals. In these various classes of vertebrates, Sertoli cells have quite different modes of proliferation and epithelial maintenance, cystic vs. tubular formation, yet accomplish essentially the same function but in strikingly different ways.

  13. Fifty years of hypersonics: where we've been, where we're going

    Energy Technology Data Exchange (ETDEWEB)

    Bertin, J.J.; Cummings, R.M. [United States Air Force Academy, CO (United States). Department of Aeronautics

    2003-10-01

    Hypersonic flight has been with us since 22 September 1963, when Robert M. White flew the North American X-15 at 4520 mph at an altitude of 354,200 ft - a Mach number of 6.7. This remarkable achievement was accomplished over six decades due to intensive research and development by a large number of scientists and engineers. In spite of that momentous achievement, designers have found the hypersonic environment to be harsh and non-forgiving. New programs since the 1960s have often uncovered the unknown unknowns, usually the hard way - early flights of new systems have often revealed problems of which the designers are unaware. Such problems include: the ineffectiveness of the body flap for the Space Shuttle Orbiter, the viscous/inviscid interactions produced by the umbilical fairings that damaged the conical section tile protection system of the Gemini Capsule, and the shock/shock interaction that damaged the X-15A-2 when it carried the hypersonic ramjet experiment. In order to continue to make advances in hypersonic flight a sustained and visionary effort is essential to generate required knowledge and technology. In order to better prepare for future developments in hypersonic flight, this article reviews the advances made within the past 50 years and then looks into the future, not just for new technological developments, but for new ways of thinking about the unknown challenges that lie ahead. (author)

  14. Fifty years of research in Balkan endemic nephropathy: where are we now?

    Energy Technology Data Exchange (ETDEWEB)

    Stefanovic, V.; Polenakovic, M. [Faculty of Medicine, Nish (Serbia)

    2009-07-01

    Despite broad investigations into the possible role of genetic factors, environmental agents and immune mechanisms, the etiology of Balkan endemic nephropathy (BEN) is only partially understood. An increased incidence of upper urothelial cancer in patients with BEN and in populations from endemic settlements has been demonstrated. Genetic studies have landed support for genetic predisposition to BEN. The similarity of the morphological and clinical pattern of BEN and Chinese herbs nephropathy has raised the possibility of a common etiologic agent, aristolochic acid (AA), described in 1969 by Ivic and confirmed by a recent study of AA-DNA adducts. Ochratoxin A (OTA) is studied extensively as the etiologic agent of BEN. Weathering of low-rank coals nearby the endemic villages produces water-soluble polycyclic aromatic hydrocarbons and aromatic amines, similar to metabolic products of acetaminophen, which has a causal relationship with analgesic nephropathy. AA is confirmed as the etiologic agent of BEN; however, it may not be the sole risk factor. More research is needed on the patterns of BEN over time and between different endemic places. Therefore, it is important to test etiological hypotheses in different endemic foci, preferably as a multicentric research. An international approach to solving the etiology of BEN is needed in the coming years. The geographic correlation and presence of AA-DNA adducts in both BEN and associated urothelial cancer support the hypothesis that these diseases share a common etiology.

  15. Fifty years of research on serotypes and mating types in Dileptus anser: A review.

    Science.gov (United States)

    Uspenskaya, Zoya I; Yudin, Alexander L

    2016-04-01

    The ciliate Dileptus anser is increasingly used as a laboratory model not only in protozoological research sensu stricto, but also in general biology. However, genetic studies of this ciliate have never been carried out, and this species is new to the comparative genetics of ciliates. This review describes the genetic experiments conducted at the Institute of Cytology of the Russian Academy of Sciences for the last 50 years. Two characters that are classical for the genetics of ciliates, serotypes and mating types were selected for analysis. The results presented do not fit into conventional genetic schemes and may have epigenetic nature. Features of this model that were revealed earlier (the simplest possible system of multiple mating types, full serial dominance of the alleles in the mat locus, the excretion of pheromones, etc.) are promising with regard to interesting comparisons of breeding systems in ciliates. The results obtained in studies of mating pheromones in D. anser have demonstrated that this model is a perspective one for further exploration of intercellular recognition in lower eukaryotes and of other related issues. Copyright © 2015 Elsevier GmbH. All rights reserved.

  16. Fifty-year trends in a box turtle population in Maryland

    Science.gov (United States)

    Hall, R.J.; Henry, P.F.P.; Bunck, C.M.

    1999-01-01

    A survey conducted in 1995 investigated long term declines reported in a population of box turtles Terrapene Carolina monitored each decade since 1945 in bottomland hardwood forest at the Patuxent Wildlife Research Center, Maryland. Methods duplicated past surveys in most respects, but were supplemented by radiotelemetry and a survey of dominant vegetation. Seventy different turtles were found on the 11.8 ha study area, a decline of >75% since peak populations were recorded in 1955. Searchers were less efficient in 1995 than in 1945-1975 for a variety of possible reasons. Among turtles recorded, approximately equal numbers persisted from each of the past five decades, with some individuals surviving >70 years. A sex ratio strongly favoring males was first recorded in 1975 and continued in 1995, but juveniles and subadults were found in greater proportion in 1995 than in any other survey. Six of nine radio-marked turtles left the bottomland study area and migrated to the adjoining bluffs to hibernate, suggesting more extensive movements and perhaps less stable home ranges than formerly thought. Age structure of trees indicated a gradual change to more shade-tolerant species. Examination of rates of change from survey data suggested that major losses probably resulted from changes in hydrology that exacerbated flooding in 1972, with recovery only beginning in 1995 and perhaps limited both by repeated flood events and successional changes in the forest. Slow recovery from losses may indicate that populations of the species would respond poorly to exploitation.

  17. Fifty years of population growth and absorption of labor in Brazil: from 1950 to 2000.

    Science.gov (United States)

    Paiva, P D

    1997-01-01

    For a long time, the Brazilian population has grown at a relatively high rate, and only recently has the process of demographic transition intensified in the country. While the associated decline in fertility could result in a future decline in the size of the working-age population, it could also lead to an increase in female participation in the labor market. Brazil's economy is performing well, with gross domestic product (GDP) growing at an average annual rate of 7.1% during 1947-80. Marked growth in industrial employment opportunities has accompanied this growth in GDP. The size of the informal sector, however, has not decreased in similar proportion, while the 1981-83 economic crisis caused urban employment levels to drop, especially in industry and construction. Moreover, the level of rural-urban migration has increased and the agricultural employment index has fallen. The author evaluates past growth trends of the Economically Active Population (EAP) and of employment in Brazil, and assesses the potential growth of the labor force until the year 2000.

  18. Homo cyborg: fifty years old Homo Ciborg: Cincuenta años después

    Directory of Open Access Journals (Sweden)

    Chris Hables Gray

    2011-12-01

    Full Text Available While the term “cyborg” is only 50 years old, the process that has produced cyborgization is much older: the evolution of the human. Humans have evolved to modify ourselves and our environment, especially through evolving culture and the technologies it creates. Culture is part of nature. Today’s mundane i-cyborgs, military drones, intimate human-machine merging and genetic engineering are a result of this; which in turn produce feelings of uncanniness, hubris, and fear. Contemporary politics must take this complex dynamic into account if we are to secure a sustainable, survivable, future for ourselves and our descendents. Social experiments such as Burning Man are a prefiguration of the kinds of (self conscious techno-social creativity needed.Mientras la terminología “ciborg” tiene apenas 50 años, son mucho más antiguos los procesos de “ciborgización”: la evolución humana. Los humanos evolucionaron para modificar su entorno y a sí mismos, especialmente a través de la cultura y las tecnologías. La cultura es parte de la naturaleza. De ella resultan los i-ciborgs mundanos de la actualidad,  los aviones militares no tripulados, la fusión íntima humano-máquina y la ingeniería genética: lo que a su vez produce sensaciones de inquietud, arrogancia y miedo. La política contemporánea debe de considerar si estamos asegurando un futuro sostenible y vivible para nuestros descendientes. Algunos experimentos sociales como el Burning Man son una prefiguración de esta necesidad creativa por la concienciación tecno-social.

  19. Comparing Socialist and Post-Socialist Television Culture. Fifty Years of Television in Croatia

    Directory of Open Access Journals (Sweden)

    Zrinjka Peruško

    2014-06-01

    Full Text Available This article builds a theoretical model for comparative analysis of media culture based on the notion of genre, and applies it to a comparative analysis of television as a cultural form in socialist and post-socialist Croatia. The paper explores how the shares and generic composition of program modes of information, entertainment and fiction change in time, and how the contribution of different genres to program flow and modes varies with the changes of political, economic and technological context. Longitudinal trends in television flows are comparatively evaluated in relation to trends in genre developments in Europe and their relationship to the changes in the cultural role of television. The results show a decrease in the information and an increase in the fiction mode between socialism and democracy, with some similarities of the Croatian and western television culture in relation to genre and mode composition and flow, albeit with a belated introduction of neo television genres. Notwithstanding the limited freedom of expression and ideological content, which necessarily influenced socialist media culture, television as a cultural form in Croatia developed in concert with the global program flows. The article is based on original content analysis of television schedules where the unit of analysis is a televisions program listing. The analogue television universe is represented by longitudinal data for 1959, 1969, 1979, 1989, 1999, and 2009. The stratified systematic sample (N=3934 for each chosen year consists of two constructed weeks from a universe of all listed programs broadcast on all free to air television channels with a national reach license.

  20. Fifty years of cytogenetics: a parallel view of the evolution of cytogenetics and genotoxicology.

    Science.gov (United States)

    Garcia-Sagredo, J M

    2008-01-01

    A parallelism exists between human cytogenetics and cytogenetic toxicology. The breakthroughs, mostly coming from and used in clinical genetics, are widely used in genetic toxicology. The birth of human cytogenetics occurred in 1956 when it was published that the diploid number of chromosomes in humans is 46. The first stage in chromosome-induced mutagenesis began in 1938 when Sax published the effects of X-rays on the chromosomes of Drosophila. In 1959, the cytogenetic anomalies for Down, Klinefelter, and Turner syndromes were described, and parallelly in 1960, the first publication on chromosomal aberrations in man caused by ionizing radiation appeared. The cytogenetic analysis of chromosomal aberrations in cell cultures is considered one of the primary methods to evaluate induced mutagenesis. At the end of the 1960s, banding techniques allowed chromosomes to be individually identified, in parallel, the sister chromatid exchange analysis technology was described. Another milestone in the history of induced mutagenesis was the discovery that mutagenic agents were able to alter chromosomal division and segregation in gonads inducing meiotic nondisjunction. Here we review new approaches and applications such as biological dosimetry, translocation scoring using FISH, and micronucleus test. Chromosomal aberrations and micronucleus test are now effective cytogenetic biomarkers of early effect used as cancer predictors. Human cytogenetics has proven to be effective over its 50-year lifespan and, although each new technique that has appeared seemed to announce its end, the fact is that the current state of cytogenetics is in reality a collection of techniques that, while common, are cheap, fast, and wide-ranging. Therefore, in genotoxicology, they continue to be useful to identify mutagenic agents as well as to evaluate and analyze exposed populations.

  1. Maternal health in fifty years of Tanzania independence: Challenges and opportunities of reducing maternal mortality.

    Science.gov (United States)

    Shija, Angela E; Msovela, Judith; Mboera, Leonard E G

    2011-12-01

    High rate of maternal death is one of the major public health concerns in Tanzania. Most of maternal deaths are caused by factors attributed to pregnancy, childbirth and poor quality of health services. More than 80% of maternal deaths can be prevented if pregnant women access essential maternity care and assured of skilled attendance at childbirth as well as emergency obstetric care. The objective of this review was to analyse maternal mortality situation in Tanzania during the past 50 years and to identify efforts, challenges and opportunities of reducing it. This paper was written through desk review of key policy documents, technical reports, publications and available internet-based literature. From 1961 to 1990 maternal mortality ratio in Tanzania had been on a downward trend from 453 to 200 per 100,000 live births. However, from 1990's there been an increasing trend to 578 per 100,000 live births. Current statistics indicate that maternal mortality ratio has dropped slightly in 2010 to 454 per 100,000 live births. Despite a high coverage (96%) in pregnant women who attend at least one antenatal clinic, only half of the women (51%) have access to skilled delivery. Coverage of emergence obstetric services is 64.5% and utilization of modern family planning method is 27%. Only about 13% of home deliveries access post natal check-up. Despite a number of efforts maternal mortality is still unacceptably high. Some of the efforts done to reduce maternal mortality in Tanzania included the following initiatives: reproductive and child survival; increased skilled delivery; maternal death audit; coordination and integration of different programs including maternal and child health services, family planning, malaria interventions, expanded program on immunization and adolescent health and nutrition programmes. These initiatives are however challenged by inadequate access to maternal health care services. In order to considerably reduce maternal deaths some of recommended

  2. Fifty Years of Botanical Gardens in China%中国植物园五十年

    Institute of Scientific and Technical Information of China (English)

    贺善安

    2002-01-01

    概述了中国140多个植物园过去50年发展的历史过程、分布和特征,以及植物园在研究、保护、展示和利用生物多样性等方面的功能.评述了中国植物园早期在经济作物烟草、药用植物薯蓣和野生果树资源研究中对社会和经济发展的贡献,以及近年来在种子科学、物种保护、经济植物引种驯化和育种等方面的理论和应用研究成果.介绍了中国植物园活植物收集的现状.其中木兰科、姜科、苏铁类、药用植物、猕猴桃属和杜鹃属等收集圃的建设已属世界领先.介绍了植物园科普和旅游的发展和中国植物园特有的盆景艺术园和硅化木收集园.%The development, distribution and features of one hundred and forty botanical gardens (BGs) in China are reported and their functions on research, conservation, display and utilization of biodiversity are summarized in this paper. The contributions to the social and economic development in the early stage of Chinese BGs with the researches of economic plant (tobacco), medicinal plant (yam) and wild fruit tree resources are evaluated. The theoretical and applied achievements in recent years in seed science, plant conservation, economic plant introduction, acclimatization and breeding are also described. A general scope of living plant collections in Chinese BGs is presented and the outstanding ones, including Magnoliaceae, Zingiberaceae, Cycadaceae, medicinal plants, Actinidia and Rhododendron are particularly mentioned. With special reference to Chinese penjing art garden and silicified wood garden, the development of scientific popularization and tourism in BGs is reviewed.

  3. Magnetite Biomineralization: Fifty years of progress, from beach-combing to the SQUID microscope

    Science.gov (United States)

    Kirschvink, J. L.; Dixson, A. D.; Raub, T.

    2012-12-01

    Magnetite biomineralization was first discovered 50 years ago as a hardening agent in the teeth of the Polyplacophoran molluscs (chitons) by the late Prof. Heinz A. Lowenstam of Caltech, when he noticed unusual erosional effects produced by their grazing in the intertidal zones of Palau (Lowenstam, 1962). Since then, biogenic magnetite has been detected in a broad range of organisms, including magnetotactic bacteria, protists, insects, fish, amphibians, reptiles, birds, and mammals including humans. In many species, the role of ferromagnetic material as a neurophysiological transducer is demonstrated clearly through the effects of pulse-remagnetization on behavior. A brief (1 uS), properly configured magnetic discharge from a rectified LC circuit, tailored to exceed the coercivity of the magnetite, will often abolish a magnetic behavioral response, or in some cases make the organism go the wrong way. This is a unique ferromagnetic effect. The genes controlling magnetite biomineralization are well characterized in several species of bacteria, and the ability of some of these bacterial genes to initiate magnetite precipitation in mammalian cell lines argues for a common descent, probably via a magnetotactic mitochondrial ancestor. Previous studies in fish reported the presence of single-domain magnetite crystals in cells near projections of the trigeminal nerve, co-located in the olfactory epithelium. Although the cells are rare, the recent development of a spinning magnetic field technique allows easy identification and isolation of these cells for individual study (Eder et al., 2012). The cells are surprisingly magnetic, with moments hundreds of times larger than typical magnetotactic bacteria. Subsequent efforts to identify the anatomical seat of magnetoreceptors have focused on the same locations in new organisms, excluding other areas. Using SQUID moment magnetometry and SQUID scanning microscopy, we report here the unexpected presence of biogenic magnetite in

  4. The big and little of fifty years of Moessbauer spectroscopy at Argonne.

    Energy Technology Data Exchange (ETDEWEB)

    Westfall, C.

    2005-09-20

    Using radioactive materials obtained by chance, a turntable employing gears from Heidelberg's mechanical toy shops, and other minimal equipment available in post World War II Germany, in 1959 Rudolf Moessbauer confirmed his suspicion that his graduate research had yielded ground-breaking results. He published his conclusion: an atomic nucleus in a crystal undergoes negligible recoil when it emits a low energy gamma ray and provides the entire energy to the gamma ray. In the beginning Moessbauer's news might have been dismissed. As Argonne nuclear physicist Gilbert Perlow noted: ''Everybody knew that nuclei were supposed to recoil when emitting gamma rays--people made those measurements every day''. If any such effect existed, why had no one noticed it before? The notion that some nuclei would not recoil was ''completely crazy'', in the words of the eminent University of Illinois condensed matter physicist Frederich Seitz. Intrigued, however, nuclear physicists as well as condensed matter (or solid state) physicists in various locations--but particularly at the Atomic Energy Research Establishment at Harwell in Britain and at Argonne and Los Alamos in the U.S.--found themselves pondering the Moessbauer spectra with its nuclear and solid state properties starting in late 1959. After an exciting year during which Moessbauer's ideas were confirmed and extended, the physics community concluded that Moessbauer was right. Moessbauer won the Nobel Prize for his work in 1961. In the 1960s and 1970s Argonne physicists produced an increasingly clear picture of the properties of matter using the spectroscopy ushered in by Moessbauer. The scale of this traditional Moessbauer spectroscopy, which required a radioactive source and other simple equipment, began quite modestly by Argonne standards. For example Argonne hosted traditional Moessbauer spectroscopy research using mostly existing equipment in the early days and

  5. Normalization Fifty Years Beyond

    DEFF Research Database (Denmark)

    Bonfils, Inge Storgaard; Tøssebro, Jan; Teittinen, Antti

    2012-01-01

    The authors discuss recent developments in services for people with intellectual disabilities (ID) in the Nordic countries. They note that all of the countries saw important reforms during the 1990s, regarding both deinstitutionalization and decentralization. However, they posit that the litmus t...

  6. Fifty years later: Emerging functions of IgE antibodies in host defense, immune regulation, and allergic diseases.

    Science.gov (United States)

    Oettgen, Hans C

    2016-06-01

    Fifty years ago, after a long search, IgE emerged as the circulating factor responsible for triggering allergic reactions. Its extremely low concentration in plasma created significant hurdles for scientists working to reveal its identity. We now know that IgE levels are invariably increased in patients affected by atopic conditions and that IgE provides the critical link between the antigen recognition role of the adaptive immune system and the effector functions of mast cells and basophils at mucosal and cutaneous sites of environmental exposure. This review discusses the established mechanisms of action of IgE in pathologic immediate hypersensitivity, as well as its multifaceted roles in protective immunity, control of mast cell homeostasis, and its more recently revealed immunomodulatory functions.

  7. Editing and publishing activities of the Korean Physical Society during the first fifty years since its inauguration in 1952

    Directory of Open Access Journals (Sweden)

    Yoon Suk Koh

    2016-08-01

    Full Text Available This is a historical review concerning the development of the editing and publishing activities of the Korean Physical Society, unique in its kind in South Korea, during its first fifty years since inauguration. It was founded in 1952, in the midst of the Korean War, and issued its first publication only in 1961. Despite such a late start, the society made great efforts to boost its activities thereafter, developing five different periodicals, including two Science Citation Index-listed journals, established by 2002. It can be seen as a remarkable success story of the Korean physics community, having overcome many hardships, which included the meager human and material resources that it started with and also the social unrest and destruction owing to the Korean War and its aftermath. The development and progress of the Korean Physical Society during this period, with a main focus on its editing and publishing practices, are briefly described.

  8. Changes in Oxidative Stress and Inflammatory Biomarkers in Fragile Adults over Fifty Years of Age and in Elderly People Exclusively Fed Enteral Nutrition

    National Research Council Canada - National Science Library

    Mesa, Maria D; Olza, Josune; Gonzalez-Anton, Carolina; Aguilera, Concepcion M; Moreno-Torres, Rosario; Jimenez, Africa; Perez de la Cruz, Antonio; Ruperez, Azahara I; Gil, Angel

    2015-01-01

    ...) affects oxidative stress and the antioxidant defence system and may improve the levels of some relevant inflammatory, and cardiovascular biomarkers in frail adults over fifty years of age and in elderly subjects...

  9. The relentless past: The effect of chronic sexual abuse in childhood on fifty years of adolescent and adult development.

    Science.gov (United States)

    Colarusso, Calvin A

    2009-01-01

    Four sisters, now in their late fifties and early sixties, were sexually abused during childhood over a four-year span by the same priest. Until recently they told no one about their experience and never received any psychological diagnostic evaluations or treatment. The author conducted detailed psychiatric evaluations of each of the four women while serving as the plaintiffs' expert witness during their lawsuits against the Catholic Church. The suits have been settled, and the women have given written permission to tell their stories. This unique clinical material provides a rare opportunity to describe and understand the ongoing, pervasive effects of untreated, chronic childhood sexual abuse on developmental processes over half a century. In each instance the women were describing the details of the abuse and the effects on their development for the first time. The severity of the pathology and the intense shame and anxiety associated with discussing their experiences after so many years raises questions about the choice of treatment and technique, particularly in regard to transference and countertransference issues.

  10. Reconstructing and analyzing China's fifty-nine year (1951–2009 drought history using hydrological model simulation

    Directory of Open Access Journals (Sweden)

    Z. Y. Wu

    2011-02-01

    Full Text Available The recent fifty-nine year (1951–2009 drought history of China is reconstructed using daily soil moisture values generated by the Variable Infiltration Capacity (VIC land surface macroscale hydrology model. VIC is applied over a grid of 10 458 points with a spatial resolution of 30 km × 30 km, and is driven by observed daily maximum and minimum air temperature and precipitation from 624 long-term meteorological stations. The VIC soil moisture is used to calculate the Soil Moisture Anomaly Percentage Index (SMAPI, which can be used as a measure of the severity of agricultural drought on a global basis. We develop a SMAPI-based drought identification procedure for practical uses in the identification of both grid point and regional drought events. As the result, a total of 325 regional drought events varying in time and strength are identified from China's nine drought study regions. These drought events can thus be assessed quantitatively at different spatial and temporal scales. The result shows that the severe drought events of 1978, 2000 and 2006 are well reconstructed, indicating SMAPI is capable of indentifying the onset of a drought event, its progressing, as well as its ending. Spatial and temporal variations of droughts on China's nine drought study regions are studied. Our result shows that on average, up to 30% of the total area of China is prone to drought. Regionally, an upward trend in drought-affected areas has been detected in three regions Inner Mongolia, Northeast and North during the recent fifty-nine years. However, the decadal variability of droughts has been week in the rest five regions South, Southwest, East, Northwest, and Tibet. Xinjiang has even been wetting steadily since the 1950s. Two regional dry centers are discovered in China as the result of a combined analysis on the occurrence of drought events from both grid points and drought study regions. The first center is located in the area partially covered by two

  11. Florence Richardson Wyckoff (1905-1997), Fifty Years of Grassroots Social ActivismVolume III: Watsonville Years 1960-1985

    OpenAIRE

    1990-01-01

    Florence Wyckoff's three-volume oral history documents her remarkable, lifelong work as a social activist, during which she has become nationally recognized as an advocate of migrant families and children. From the depression years through the 1970s, she pursued grassroots, democratic, community-building efforts in the service of improving public health standards and providing health care, education, and housing for migrant families. Major legislative milestones in her career of advocacy were...

  12. Thirty-five-year results after Charnley total hip arthroplasty in patients less than fifty years old. A concise follow-up of previous reports.

    Science.gov (United States)

    Warth, Lucian C; Callaghan, John J; Liu, Steve S; Klaassen, Alison L; Goetz, Devon D; Johnston, Richard C

    2014-11-05

    We report the updated results for a previously described cohort of patients who were less than fifty years old at the time of the index Charnley total hip arthroplasty with cement. The original cohort consisted of ninety-three consecutive hips in sixty-nine patients. The patients were followed for a minimum of thirty-five years after surgery or until death. At the latest follow-up evaluation, there were forty-one total hip replacements (44%) in thirty-two living patients. Thirty-four (37%) of the ninety-three total hip replacements in the original cohort had been revised or removed. Twenty acetabular (22%) and seven femoral (8%) components had been revised for aseptic loosening. Since the twenty-five-year follow-up, the average six-minute-walk distance decreased from 395 m to 171 m, and this decrease correlated with increasing comorbidity. This study demonstrates the durability of cemented total hip replacements in a young patient population. Although 63% (fifty-nine) of the ninety-three original hip replacements were functioning at the latest follow-up or at the time of death, a significant decrease in activity level was seen over time (p < 0.001). Of the forty-one original implants in the patients who were alive at the time of the thirty-five-year follow-up, only 46% (nineteen) were retained. Copyright © 2014 by The Journal of Bone and Joint Surgery, Incorporated.

  13. Genetic diversity of rice cultivars (Oryza sativa L.) in China and the temporal trends in recent fifty years

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    To understand geographical distribution of the genetic diversity of rice cultivars (Oryza sativa L.) and its trends in recent fifty years in China, 453 accessions were analyzed by 36 microsatellites loci and 42 phenotypic traits. Results revealed that the genetic diversity by SSRs is highly consistent with that by phenotypic traits and the genetic diversity of indica cultivars was higher than that of japonica cultivars; the genetic diversity of cultivars declined from 1950s to 1980s and then increased greatly; among the six rice ecological zones (REZs), genetic diversity of REZⅡ was the highest and those of REZⅤ and REZⅥ were the lowest at both DNA and phenotypic level. Jiangsu and Jiangxi provinces in the middle and lower reaches of Yangtze River and Sichuan province in southwest of China were the areas with the highest genetic diversity. Breeders in REZⅤ which is an important japonica rice area but with very low genetic diversity should explore more gene resources to widen the genetic backgrounds of cultivars.

  14. Fifty Years of Magnetic Fusion Research (1958–2008: Brief Historical Overview and Discussion of Future Trends

    Directory of Open Access Journals (Sweden)

    Laila A. El-Guebaly

    2010-06-01

    Full Text Available Fifty years ago, the secrecy surrounding magnetically controlled thermonuclear fusion had been lifted allowing researchers to freely share technical results and discuss the challenges of harnessing fusion power. There were only four magnetic confinement fusion concepts pursued internationally: tokamak, stellarator, pinch, and mirror. Since the early 1970s, numerous fusion designs have been developed for the four original and three new approaches: spherical torus, field-reversed configuration, and spheromak. At present, the tokamak is regarded worldwide as the most viable candidate to demonstrate fusion energy generation. Numerous power plant studies (>50, extensive R&D programs, more than 100 operating experiments, and an impressive international collaboration led to the current wealth of fusion information and understanding. As a result, fusion promises to be a major part of the energy mix in the 21st century. The fusion roadmaps developed to date take different approaches, depending on the anticipated power plant concept and the degree of extrapolation beyond ITER. Several Demos with differing approaches will be built in the US, EU, Japan, China, Russia, Korea, India, and other countries to cover the wide range of near-term and advanced fusion systems.

  15. From conditioning to learning communities: implications of fifty years of research in e-learning interaction design

    Directory of Open Access Journals (Sweden)

    Andrew Ravenscroft

    2003-12-01

    Full Text Available This paper will consider e-learning in terms of the underlying learning processes and interactions that are stimulated, supported or favoured by new media and the contexts or communities in which it is used. We will review and critique a selection of research and development from the past fifty years that has linked pedagogical and learning theory to the design of innovative e-learning systems and activities, and discuss their implications. It will include approaches that are, essentially, behaviourist (Skinner and Gagné, cognitivist (Pask, Piaget and Papert, situated (Lave, Wenger and Seely-Brown, socioconstructivist (Vygotsky, socio-cultural (Nardi and Engestrom and community-based (Wenger and Preece. Emerging from this review is the argument that effective elearning usually requires, or involves, high-quality educational discourse, that leads to, at the least, improved knowledge, and at the best, conceptual development and improved understanding. To achieve this I argue that we need to adopt a more holistic approach to design that synthesizes features of the included approaches, leading to a framework that emphasizes the relationships between cognitive changes, dialogue processes and the communities, or contexts for e-learning.

  16. Fifty Years of Pulsar Candidate Selection: From simple filters to a new principled real-time classification approach

    CERN Document Server

    Lyon, R J; Cooper, S; Brooke, J M; Knowles, J D

    2016-01-01

    Improving survey specifications are causing an exponential rise in pulsar candidate numbers and data volumes. We study the candidate filters used to mitigate these problems during the past fifty years. We find that some existing methods such as applying constraints on the total number of candidates collected per observation, may have detrimental effects on the success of pulsar searches. Those methods immune to such effects are found to be ill-equipped to deal with the problems associated with increasing data volumes and candidate numbers, motivating the development of new approaches. We therefore present a new method designed for on-line operation. It selects promising candidates using a purpose-built tree-based machine learning classifier, the Gaussian Hellinger Very Fast Decision Tree (GH-VFDT), and a new set of features for describing candidates. The features have been chosen so as to i) maximise the separation between candidates arising from noise and those of probable astrophysical origin, and ii) be as...

  17. Fifty Years of Pulsar Candidate Selection: From simple filters to a new principled real-time classification approach

    Science.gov (United States)

    Lyon, R. J.; Stappers, B. W.; Cooper, S.; Brooke, J. M.; Knowles, J. D.

    2016-06-01

    Improving survey specifications are causing an exponential rise in pulsar candidate numbers and data volumes. We study the candidate filters used to mitigate these problems during the past fifty years. We find that some existing methods such as applying constraints on the total number of candidates collected per observation, may have detrimental effects on the success of pulsar searches. Those methods immune to such effects are found to be ill-equipped to deal with the problems associated with increasing data volumes and candidate numbers, motivating the development of new approaches. We therefore present a new method designed for on-line operation. It selects promising candidates using a purpose-built tree-based machine learning classifier, the Gaussian Hellinger Very Fast Decision Tree (GH-VFDT), and a new set of features for describing candidates. The features have been chosen so as to i) maximise the separation between candidates arising from noise and those of probable astrophysical origin, and ii) be as survey-independent as possible. Using these features our new approach can process millions of candidates in seconds (˜1 million every 15 seconds), with high levels of pulsar recall (90%+). This technique is therefore applicable to the large volumes of data expected to be produced by the Square Kilometre Array (SKA). Use of this approach has assisted in the discovery of 20 new pulsars in data obtained during the LOFAR Tied-Array All-Sky Survey (LOTAAS).

  18. 50 años de música electroacústica en Chile Electroacustic Music in Chile: Fifty years

    Directory of Open Access Journals (Sweden)

    Federico Schumacher Ratt

    2007-12-01

    Full Text Available Cincuenta años han pasado desde que León Schidlowsky compusiera Nacimiento, la primera obra electroacústica chilena. Cincuenta años de una historia a menudo desconocida, compuesta de algunos éxitos resonantes, de desarrollos a veces truncos y de silencios bastante expresivos. La música electroacústica en Chile ha tenido un desarrollo pendular: de momentos de gran pasión e interés ha pasado al desconocimiento casi absoluto, y viceversa. A pesar de ya medio siglo de historia en el país -y algo más en el mundo- pareciera que los alcances y posibilidades de la música electroacústica, o más bien del concepto que en ella subyace (la tecnología aplicada a la música, en este caso más precisamente, la informática musical, no son en nuestro medio aún lo suficientemente bien analizados, comprendidos y proyectados en cuanto a la producción musical actual y futura. En este artículo, intentamos aproximarnos a las posibilidades y exigencias que ofrece actualmente esta disciplina desde el punto de vista del análisis, de la composición y de la interpretación musical. Como ubicación, se revisará algo de nuestra historia poniendo el acento en los extremos, en sus inicios y en los años que nos son más próximosFifty years ago, León Schidlowsky wrote Nacimiento (Birth, the first electroacustic work in composed Chile. Fifty years have elapsed of a history which very frequently has been forgotten. It is mude up of resounding achievements, periods of development, sometimes interrupted, and very meaningful gaps. Like a pendulum, electroacustic music in Chile has swung from periods of great passion and interest to other periods when has been practically ignored, and viceversa. In spite of almost half a century of history in Chile and a slightly longer period in the world, it would seem that the extent and possibilities of electroacustic music or better, the concept underlying this music -a technology applied to music, or more precisely to

  19. The cost of postgraduate medical education and continuing medical education: re-examining the status fifty years back.

    Science.gov (United States)

    Walsh, Kieran

    2015-03-01

    The subject of the cost and value of medical education is becoming increasingly important. However, this subject is not a new one. Fifty years ago, Mr. DH Patey, Dr. OF Davies, and Dr. John Ellis published a report on the state of postgraduate medical education in the UK. The report was wide-ranging, but it made a considerable mention of cost. In this short article, I have presented the documentary research that I conducted on their report. I have analyzed it from a positivist perspective and have concentrated on the subject of cost, as it appears in their report. The authors describe reforms within postgraduate medical education; however, they are clear from the start that the issue of cost can often be a barrier to such reforms. They state the need for basic facilities for medical education, but then outline the financial barriers to their development. The authors then discuss the costs of library services for education. They state that the "annual spending on libraries varies considerably throughout the country." The authors also describe the educational experiences of newly graduated doctors. According to them, the main problem is that these doctors do not have time to attend formal educational events, and that this will not be possible until there is "a more graduated approach to responsible clinical work," something which is not possible without financial investment. While concluding their report, the authors state that the limited money invested in postgraduate medical education and continuing medical education has been well spent, and that this has had a dual effect on improving medical education as well as the standards of medical care.

  20. Long-term results of a modified Spitzy shelf operation for residual hip dysplasia and subluxation. A fifty year follow-up study of fifty six children and young adults.

    Science.gov (United States)

    Holm, Anne Guro Vreim; Reikerås, Olav; Terjesen, Terje

    2017-02-01

    The purposes of this study were to establish long-term outcome of the Spitzy shelf-operation and evaluate whether the procedure would delay osteoarthritis. During 1954-1976, 56 patients (70 hips) underwent Spitzy shelf operation at a mean age of 11.9 years (5 to 22). Indications included residual hip dysplasia or subluxation with Centre-Edge angle shelf operation. Survival was assessed by Cox regression. Univariable Cox regression was performed separately for each variable. Potential predictors (p-value shelf procedure was 39.9 years (21 to 53). Survival fell from 83 % 30 years post-operatively, to 22 % at 50 years. Fifty-three hips (76 %) had undergone total hip replacement at mean age of 49.4 years (33 to 64). Seventeen hips had not received total hip replacement, mean survival 47.9 years (39 to 53). The study showed that Spitzy shelf-operation had satisfactory long-term outcome with hip-survival in almost 90 % at patient age 40 years. The results indicate that Spitzy shelf-operation postpone total hip replacement. We consider Spitzy shelf-operation a good alternative in patients above 8 years. In younger children the procedure is not recommended due to increased frequency of graft resorption.

  1. An Ode to Stuart Hall's "The Supply of Demand": The Case of Post-Secondary Education in Ontario Fifty Years Later

    Science.gov (United States)

    FitzGerald Murphy, Maggie

    2016-01-01

    Despite the fact that over fifty years have passed since its publication, Stuart Hall's article "The Supply of Demand" (1960), is remarkably relevant today. The central message that society must not be blinded by "prosperity" such that it no longer envisions and demands a better world is especially pertinent in light of the…

  2. Secular Changes of Adiposity and Motor Development in Czech Preschool Children: Lifestyle Changes in Fifty-Five Year Retrospective Study

    OpenAIRE

    Petr Sedlak; Jana Pařízková; Robert Daniš; Hana Dvořáková; Jana Vignerová

    2015-01-01

    Secular trends of adiposity and motor development in preschool children since the fifties of the last century up to the beginning of this millennium were analyzed so as to reveal possible changes due to continuously differentiating lifestyle. In preschool children (n = 3678) height, weight, skinfold thickness over triceps, subscapular, and suprailiac were measured by Harpenden caliper in 1957, 1977, 1980, 1985, 1990, and 2012. Simultaneously, motor performance was tested by evaluating the ach...

  3. Fifty-year old and still ticking.... an interview with Emile Zuckerkandl on the 50th anniversary of the molecular clock. Interview by Giacomo Bernardi.

    Science.gov (United States)

    Zuckerkandl, Emile

    2012-06-01

    In 1962, a young post-doctoral fellow and a prominent Nobel Prize winner, Emile Zuckerkandl and Linus Pauling, published a seminal paper that described the relationship between the average number of aminoacid replacements and divergence time, known as the molecular clock (Zuckerkandl and Pauling 1962). Fifty years after the original publication, I was fortunate enough to interview Emile Zuckerkandl. We shared thoughts on his life and the historical events that led to the discovery of the molecular clock.

  4. Secular Changes of Adiposity and Motor Development in Czech Preschool Children: Lifestyle Changes in Fifty-Five Year Retrospective Study

    Science.gov (United States)

    Sedlak, Petr; Pařízková, Jana; Daniš, Robert; Dvořáková, Hana; Vignerová, Jana

    2015-01-01

    Secular trends of adiposity and motor development in preschool children since the fifties of the last century up to the beginning of this millennium were analyzed so as to reveal possible changes due to continuously differentiating lifestyle. In preschool children (n = 3678) height, weight, skinfold thickness over triceps, subscapular, and suprailiac were measured by Harpenden caliper in 1957, 1977, 1980, 1985, 1990, and 2012. Simultaneously, motor performance was tested by evaluating the achievements in broad jump and throwing a ball, as a marker of adaptation to changing level of physical activity, free games, and exercise. Along the period of five decades the values of skinfold thickness increased significantly until 2012, mainly on the trunk. Simultaneously, the level of motor performance significantly decreased. Modifications of the way of life during the mentioned five decades characterized by sedentarism and inadequate food intake as related to energy output influenced negatively both adiposity and motor performance already in preschool children. Mostly increased deposition of fat on the trunk which is considered as a marker of possible development of metabolic syndrome was apparent already in preschool age, indicating the importance of early intervention concerning also physical activity and availability for exercise since early life. PMID:26380296

  5. Secular Changes of Adiposity and Motor Development in Czech Preschool Children: Lifestyle Changes in Fifty-Five Year Retrospective Study.

    Science.gov (United States)

    Sedlak, Petr; Pařízková, Jana; Daniš, Robert; Dvořáková, Hana; Vignerová, Jana

    2015-01-01

    Secular trends of adiposity and motor development in preschool children since the fifties of the last century up to the beginning of this millennium were analyzed so as to reveal possible changes due to continuously differentiating lifestyle. In preschool children (n = 3678) height, weight, skinfold thickness over triceps, subscapular, and suprailiac were measured by Harpenden caliper in 1957, 1977, 1980, 1985, 1990, and 2012. Simultaneously, motor performance was tested by evaluating the achievements in broad jump and throwing a ball, as a marker of adaptation to changing level of physical activity, free games, and exercise. Along the period of five decades the values of skinfold thickness increased significantly until 2012, mainly on the trunk. Simultaneously, the level of motor performance significantly decreased. Modifications of the way of life during the mentioned five decades characterized by sedentarism and inadequate food intake as related to energy output influenced negatively both adiposity and motor performance already in preschool children. Mostly increased deposition of fat on the trunk which is considered as a marker of possible development of metabolic syndrome was apparent already in preschool age, indicating the importance of early intervention concerning also physical activity and availability for exercise since early life.

  6. Secular Changes of Adiposity and Motor Development in Czech Preschool Children: Lifestyle Changes in Fifty-Five Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    Petr Sedlak

    2015-01-01

    Full Text Available Secular trends of adiposity and motor development in preschool children since the fifties of the last century up to the beginning of this millennium were analyzed so as to reveal possible changes due to continuously differentiating lifestyle. In preschool children (n=3678 height, weight, skinfold thickness over triceps, subscapular, and suprailiac were measured by Harpenden caliper in 1957, 1977, 1980, 1985, 1990, and 2012. Simultaneously, motor performance was tested by evaluating the achievements in broad jump and throwing a ball, as a marker of adaptation to changing level of physical activity, free games, and exercise. Along the period of five decades the values of skinfold thickness increased significantly until 2012, mainly on the trunk. Simultaneously, the level of motor performance significantly decreased. Modifications of the way of life during the mentioned five decades characterized by sedentarism and inadequate food intake as related to energy output influenced negatively both adiposity and motor performance already in preschool children. Mostly increased deposition of fat on the trunk which is considered as a marker of possible development of metabolic syndrome was apparent already in preschool age, indicating the importance of early intervention concerning also physical activity and availability for exercise since early life.

  7. Recovery dynamics and invasibility of herbaceous plant communities after exposure to fifty-year climate extremes in different seasons

    Directory of Open Access Journals (Sweden)

    F. E. Dreesen

    2013-10-01

    Full Text Available Disturbance events such as climatic extremes may enhance the invasibility of plant communities, through the creation of gaps and the associated local increase in available resources. In this study, experimental herbaceous communities consisting of three species were subjected to 50 yr extreme drought and/or heat events, in spring, summer or autumn. In the year of the induced extremes, species mortality and end-of-season biomass were examined. In two subsequent years without further disturbances, establishment of new species was recorded. The drought and drought + heat extremes in summer and autumn induced greater plant mortality compared with the heat extremes in those seasons and compared with all extremes applied in spring, in all three originally planted species. Recovery in terms of biomass towards the end of the growing season, however, was species-specific. The dominant species, the nitrogen fixer Trifolium repens, recovered poorly from the drought and drought + heat extremes which governed the community response. Community biomass, which was heavily affected by the drought and especially by the drought + heat events in summer and autumn, reached control values already one year later. Invasibility was increased in the communities that underwent the drought + heat extremes in the first year following the extreme events, but no longer in the second year. During the two years of invasion, the community composition changed, but independently of the type and impact of the extreme event. In short, the extreme climate events greatly affected the survival and productivity of the species, modified the species composition and dominance patterns, and increased the invasibility of our plant communities. However, none of these community properties seemed to be affected in the long term, as the induced responses faded out after one or two years.

  8. 成批烧伤救治50年%Experiences in rescue and treatment of mass burn casualties in fifty years

    Institute of Scientific and Technical Information of China (English)

    周一平

    2008-01-01

    The article reviewed the history and the main experiences of rescue of mass burn casualties and their treatment during the past fifty years in China. Some issues including medical support for mass burn casually and treatment regime in future, such as the prevention of burn calamities, further elevation of the eure rate and lowering in the rate of disability, further development in network of burn care and preliminary scheme of rescue of mass burn casualties and their treatment, accelerating the development and study on the substitutes of allo-skin graft were discussed.

  9. The Meta-Analysis of Clinical Judgment Project: Fifty-Six Years of Accumulated Research on Clinical Versus Statistical Prediction

    Science.gov (United States)

    Aegisdottir, Stefania; White, Michael J.; Spengler, Paul M.; Maugherman, Alan S.; Anderson, Linda A.; Cook, Robert S.; Nichols, Cassandra N.; Lampropoulos, Georgios K.; Walker, Blain S.; Cohen, Genna; Rush, Jeffrey D.

    2006-01-01

    Clinical predictions made by mental health practitioners are compared with those using statistical approaches. Sixty-seven studies were identified from a comprehensive search of 56 years of research; 92 effect sizes were derived from these studies. The overall effect of clinical versus statistical prediction showed a somewhat greater accuracy for…

  10. Oak Ridge National Laboratory [ORNL] Review, Vol. 25, Nos. 3 and 4, 1992 [The First Fifty Years

    Science.gov (United States)

    Krause, C.(ed.)

    1992-01-01

    In observation of the 50th anniversary of Oak Ridge National Laboratory, this special double issue of the Review contains a history of the Laboratory, complete with photographs, drawings, and short accompanying articles. Table of contents include: Wartime Laboratory; High-flux Years; Accelerating Projects; Olympian Feats; Balancing Act; Responding to Social Needs; Energy Technologies; Diversity and Sharing; Global Outreach; Epilogue

  11. Fifty years of Brazilian Dental Materials Group: scientific contributions of dental materials field evaluated by systematic review

    OpenAIRE

    Wellington Luiz de Oliveira ROSA; Tiago Machado SILVA; Lima, Giana da Silveira; SILVA, Adriana Fernandes; Piva,Evandro

    2016-01-01

    ABSTRACT Objective A systematic review was conducted to analyze Brazilian scientific and technological production related to the dental materials field over the past 50 years. Material and Methods This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (Prisma) statement. Searches were performed until December 2014 in six databases: MedLine (PubMed), Scopus, LILACS, IBECS, BBO, and the Cochrane Library. Additionally, the Brazilian patent database (INPI -...

  12. Lauriston S. Taylor lecture: fifty years of scientific research: the importance of scholarship and the influence of politics and controversy.

    Science.gov (United States)

    Brent, Robert L

    2007-11-01

    Over the past 50 years our laboratory has performed and published many studies in the fields of teratology, radiation biology and radiation embryology. The early work took place when I was a research employee at the University of Rochester Manhattan Project in 1944 and where I had my introduction to embryology and genetics. Over the years our lab has provided consultations dealing with the risks of various environmental toxicant exposures during pregnancy. With the advent of the Internet, consulting has become more rapid and efficient. In the past year our pregnancy Web site of the Health Physics Society received approximately 154,000 hits, of which over a thousand contacts were still quite anxious after reading the Web site answers and requested a personal consultation. From this extensive experience we have learned that many physicians and other counselors are not prepared to counsel patients concerning radiation risks. Approximately 8% of the patient contacts who have consulted a professional have been provided with inaccurate information that would have resulted in an unnecessary interruption of a wanted pregnancy. There are five areas of radiation embryology that are considered to be controversial. 1) Can the fetus be harmed by ionizing radiation if the fetus is not directly exposed? 2) Is the production of mental retardation from radiation during pregnancy a threshold phenomenon? 3) Does fractionation and protraction of radiation decrease the magnitude of the reproductive and developmental risks? 4) Is there a period during pregnancy when radiation will result in an increased mortality but not an increase in malformations? 5) How sensitive is the fetus to the oncogenic effects of radiation? We utilize the scientific information obtained from studies in these five areas to counsel patients concerning pregnancy radiation risks. The willingness and persistence of scientists to debate the controversial aspects of this research and apply the best available

  13. A vision for the second fifty years of nuclear energy. Vision and strategies; Wizja drugiego piecdziesieciolecia energetyki jadrowej

    Energy Technology Data Exchange (ETDEWEB)

    Hori, M. [International Nuclear Societies Council (Poland)] [and others

    1997-12-31

    The paper is the Polish issue of the report worked out by International Nuclear Societies Council published in 1996. The report contains the experts opinion on development of nuclear energy and applications of radiation techniques and sources worldwide during the next 50 years. The worldwide energy demand prognosis as well as needs of different branches of industry, agriculture, medicine, etc. have been taken into account. The broad spectrum of aspects (safety assurance, economy, environmental impacts) connected with nuclear technology utilization has been also discussed. Transl., 24 refs, 6 figs, 6 tabs.

  14. Suicides in Serbia at the beginning of the 21st century and trends in the past fifty years

    Directory of Open Access Journals (Sweden)

    Penev Goran

    2007-01-01

    Full Text Available In 2006 in Serbia, 1444 persons committed suicide (19.5 per 100.000 population. Compared to the early 50s of the 20th century, the number of suicides has nearly doubled, but there has been a moderate decrease in the last 15 years. Similar, but somewhat more moderate tendencies are noted in the change of the value of the suicide rates. The lowest suicide rates were recorded during the 1950s, around 12 per 100.000, and the highest in the last decade of the 20th century when the rate reached 20 suicides per 100.000 inhabitants. The highest suicide rate is among the elderly, and there is also a noticeable tendency of increase in the share of the elderly in the total number of suicides, which is primarily the consequence of intense demographic aging. With youth, the last thirty years note a decline of both the number of suicides and the value of the suicide rates. The number of young people aged 15-24 who have committed suicide in 2006 is less than half of the number from 1971 (decreased from 150 to 66, and the values of suicide rates are also significantly low (decreased from 11.5 to 6.9 per 100.000. Despite certain changes in the values of age-specific suicide rates achieved in the last 50 years, their age patterns of suicide mortality can be characterized as stable. Men are dominant among persons who have committed suicide, with double the number of women, and the highest recorded value of the suicide rate of women never surpassed the value of the lowest suicide rate in men. In terms of marital status, the total rate of suicides is highest with widowers then divorced persons, married persons, and lowest rates are with celibates. In all four groups, suicide rates are at least 3 times higher for men. There is also a clear connection between the level of education and suicide rates for both sexes, with the suicide rate decreasing with higher educational level. In terms of total suicide rate, Serbia is currently in the top half of the European list of

  15. Extended radical mastectomy versus simple mastectomy followed by radiotherapy in primary breast cancer. A fifty-year follow-up to the Copenhagen Breast Cancer randomised study

    Energy Technology Data Exchange (ETDEWEB)

    Johansen, Helge; Kaae, Sigvard (Radium Center, Finsen Inst., Copenhagen (Denmark)); Jensen, Maj-Britt; Mouridsen, Henning T. (DBCG Registry, Copenhagen (Denmark))

    2008-05-15

    From November 1951 to December 1957, 666 consecutive patients with untreated primary breast cancer admitted to the Radium Center in Copenhagen were randomised before their operability was evaluated into two groups, simple mastectomy with postoperative radiotherapy or extended radical mastectomy. Following physical examination 241 of the patients were excluded, primarily due to tumours deemed inoperable due to clinical criteria (n =107) and due to poor general condition (n =69). Twenty-five years results of disease-free free survival and fifty years results of survival are presented, showing no difference between the two groups. Patients with clinical stage I did significantly better than patients with stage II-III tumours. Patients with grade I tumours had a better survival than patients with grade II-III. The breast cancer associated mortality was lower in premenopausal patients compared to postmenopausal patients. An excess mortality due to breast cancer was evident up to 20-25 years following the primary diagnosis

  16. Extended radical mastectomy versus simple mastectomy followed by radiotherapy in primary breast cancer. A fifty-year follow-up to the Copenhagen Breast Cancer randomised study.

    Science.gov (United States)

    Johansen, Helge; Kaae, Sigvard; Jensen, Maj-Britt; Mouridsen, Henning T

    2008-01-01

    From November 1951 to December 1957, 666 consecutive patients with untreated primary breast cancer admitted to the Radium Center in Copenhagen were randomised before their operability was evaluated into two groups, simple mastectomy with postoperative radiotherapy or extended radical mastectomy. Following physical examination 241 of the patients were excluded, primarily due to tumours deemed inoperable due to clinical criteria (n =107) and due to poor general condition (n =69). Twenty-five years results of disease-free free survival and fifty years results of survival are presented, showing no difference between the two groups. Patients with clinical stage I did significantly better than patients with stage II-III tumours. Patients with grade I tumours had a better survival than patients with grade II-III. The breast cancer associated mortality was lower in premenopausal patients compared to postmenopausal patients. An excess mortality due to breast cancer was evident up to 20-25 years following the primary diagnosis.

  17. Fifty years of Weibel-Palade bodies: the discovery and early history of an enigmatic organelle of endothelial cells.

    Science.gov (United States)

    Weibel, E R

    2012-06-01

    In 1962, a rod-shaped cytoplasmic organelle of endothelial cells, later called the Weibel-Palade body, was serendipitously discovered by electron microscopy. It contains a set of parallel tubules and is wrapped in a membrane. Subsequent studies in the following decades established the unique localization of this organelle in endothelial cells of all vertebrates studied, meaning that it could serve as a marker of endothelial cells in tissue cultures. However, these studies did not reveal its functional significance, except for an indication that it could be related to an undefined thromboplastic substance. Twenty years after its discovery as a structural entity, it was shown by others that it houses von Willebrand factor and is thus clearly related to the coagulation system. In this review, I provide a personal historical account of the discovery and the subsequent limited work that I carried out on the organelle, putting it in the perspective of the current state of knowledge after half a century of research by many scientists.

  18. Fifty years of Brazilian Dental Materials Group: scientific contributions of dental materials field evaluated by systematic review

    Directory of Open Access Journals (Sweden)

    Wellington Luiz de Oliveira ROSA

    Full Text Available ABSTRACT Objective A systematic review was conducted to analyze Brazilian scientific and technological production related to the dental materials field over the past 50 years. Material and Methods This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (Prisma statement. Searches were performed until December 2014 in six databases: MedLine (PubMed, Scopus, LILACS, IBECS, BBO, and the Cochrane Library. Additionally, the Brazilian patent database (INPI - Instituto Nacional de Propriedade Industrial was screened in order to get an overview of Brazilian technological development in the dental materials field. Two reviewers independently analyzed the documents. Only studies and patents related to dental materials were included in this review. Data regarding the material category, dental specialty, number of documents and patents, filiation countries, and the number of citations were tabulated and analyzed in Microsoft Office Excel (Microsoft Corporation, Redmond, Washington, United States. Results A total of 115,806 studies and 53 patents were related to dental materials and were included in this review. Brazil had 8% affiliation in studies related to dental materials, and the majority of the papers published were related to dental implants (1,137 papers, synthetic resins (681 papers, dental cements (440 papers, dental alloys (392 papers and dental adhesives (361 papers. The Brazilian technological development with patented dental materials was smaller than the scientific production. The most patented type of material was dental alloys (11 patents, followed by dental implants (8 patents and composite resins (7 patents. Conclusions Dental materials science has had a substantial number of records, demonstrating an important presence in scientific and technological development of dentistry. In addition, it is important to approximate the relationship between academia and industry to expand the technological development

  19. Fifty years of Brazilian Dental Materials Group: scientific contributions of dental materials field evaluated by systematic review

    Science.gov (United States)

    ROSA, Wellington Luiz de Oliveira; SILVA, Tiago Machado; LIMA, Giana da Silveira; SILVA, Adriana Fernandes; PIVA, Evandro

    2016-01-01

    ABSTRACT Objective A systematic review was conducted to analyze Brazilian scientific and technological production related to the dental materials field over the past 50 years. Material and Methods This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (Prisma) statement. Searches were performed until December 2014 in six databases: MedLine (PubMed), Scopus, LILACS, IBECS, BBO, and the Cochrane Library. Additionally, the Brazilian patent database (INPI - Instituto Nacional de Propriedade Industrial) was screened in order to get an overview of Brazilian technological development in the dental materials field. Two reviewers independently analyzed the documents. Only studies and patents related to dental materials were included in this review. Data regarding the material category, dental specialty, number of documents and patents, filiation countries, and the number of citations were tabulated and analyzed in Microsoft Office Excel (Microsoft Corporation, Redmond, Washington, United States). Results A total of 115,806 studies and 53 patents were related to dental materials and were included in this review. Brazil had 8% affiliation in studies related to dental materials, and the majority of the papers published were related to dental implants (1,137 papers), synthetic resins (681 papers), dental cements (440 papers), dental alloys (392 papers) and dental adhesives (361 papers). The Brazilian technological development with patented dental materials was smaller than the scientific production. The most patented type of material was dental alloys (11 patents), followed by dental implants (8 patents) and composite resins (7 patents). Conclusions Dental materials science has had a substantial number of records, demonstrating an important presence in scientific and technological development of dentistry. In addition, it is important to approximate the relationship between academia and industry to expand the technological development in

  20. Changes in Oxidative Stress and Inflammatory Biomarkers in Fragile Adults over Fifty Years of Age and in Elderly People Exclusively Fed Enteral Nutrition

    Directory of Open Access Journals (Sweden)

    Maria D. Mesa

    2016-01-01

    Full Text Available We aim to evaluate whether exclusive feeding of an enteral formula enriched with n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA affects oxidative stress and the antioxidant defence system and may improve the levels of some relevant inflammatory, and cardiovascular biomarkers in frail adults over fifty years of age and in elderly subjects. Fifty-five patients were divided into two groups and were exclusively fed a newly designed normoproteic and isocaloric enteral formula enriched with eicosapentaenoic (98 mg/d and docosahexaenoic acids (46 mg/d (n=26 or a reference enteral diet (n=29. Oxidative, inflammatory and cardiovascular risk biomarkers and red blood cell fatty acid profiles were determined at the beginning and after 90 and 180 days of feeding. The n-3 LC-PUFA percentage tended to be higher (P=0.053 in the experimental group than in the reference group. Administration of the n-3 LC-PUFA diet did not increase oxidative stress or modify plasma antioxidant capacity but decreased antioxidant enzymatic activities. MMP-9 plasma concentration decreased with both formulae, whereas tPAI-1 tended to decrease (P=0.116 with the administration of the experimental formula. In conclusion, administration of the new n-3 LC-PUFA-enriched product for 6 months did not negatively alter the oxidative status and improved some cardiovascular risk biomarkers.

  1. Fifty Years of Matter Waves

    Science.gov (United States)

    Medicus, Heinrich A.

    1974-01-01

    Discusses the origin of de Broglie's concept and its influences on his contemporaries, notably on Einstein, Schrodinger, Elsasser, Davisson, and Thomson. Indicates that the theory served not only as the starting point of quantum mechanics, but also opened new experimental possibilities. Historical inaccuracies are corrected with new material…

  2. A ten years follow-up of the results of surgery for Dupuytren's disease. A study of fifty-eight cases.

    Science.gov (United States)

    Norotte, G; Apoil, A; Travers, V

    1988-01-01

    Fifty-eight patients (52 males and 6 females) operated on for Dupuytren contracture were examined by the same author with a more than ten year follow-up. At time of surgery the average was 55 years old. 69 hands (169 fingers) rated 4.33 according to the simplified Tubiana's score were treated by the same operative procedure: Mac Indoe's incision, digital Z plasty (if needed), subtotal fasciectomy and physiotherapy beginning 8 days postoperatively. At long term, recurrence appears for 49 hands (71%) one every two in the two first postoperative years, one out of five after five years. 24 of them were graded stage I. The recurrence appeared 14 times associated with an extension of the disease and the earlier, the higher was the initial stage. Some factors seem to be of a bad prognosis regarding recurrence: age (93% of recurrence under 50 years old) Ledderhose or Lapeyronie (100%) other associated diseases (Alcoholism, diabetes mellitus, epilepsy) and severe preoperative stage. Subjective results are good: 45 patients are satisfied and only 3 underwent a second operation.

  3. 郭沫若文学研究五十年%Retrospect on Studies of Guo Mo-ruo' Writings in the Past Fifty Years

    Institute of Scientific and Technical Information of China (English)

    朱寿桐

    2001-01-01

    郭沫若文学研究是中国现代文学研究的一个重要组成部分。新中国成立后的50年间,它应合着中国现代文学学科的发展节拍而发展。三次研究高潮取得了堪称辉煌的学术成就,演化了一个逐步摆脱政治化规约的建构学术品格的历史。%Studies of Guo Mo-Ruo' writings form essential parts in academic studies of modern Chinese literature. Since the foundation of New China in 1949, researches in both fields have been developing with almost the same speed. In the past fifty years, there have been three high tides in the studies of Guo Mo-ruo''s writings, which gained brilliant academic achievements. It is also a history of constructing high academic quality and style by gradually shaking off the bonds of political interference.

  4. [Fifty years of research on tuberculosis. Lessons I have learnt during 50 years and topics to be investigated in the future].

    Science.gov (United States)

    Shimao, T

    2000-07-01

    I have engaged in the research on tuberculosis for 50 years, and lessons I have learnt during this period could be summarized in the following ten topics. First is great research achievements by our predecessors on the establishment of so-called primary infection theory on the pathogenesis of TB, planning of TB control principles based on the theory and development of new technologies used for TB control, such as mass miniature X-ray examination and BCG vaccination in 1920s and 1930s. TB control law was enforced in 1951, and the modern TB programme was initiated. Second, the field is a treasure house of interesting data. Several interesting data on TB soon after the World War II in Tokyo and a rural area were collected and analyzed from the mass health examination. Third, looking at the increase of tuberculin positivity with age, it was found that the tuberculin negativity decreased as the exponential function of age, and the current concept of the annual risk of TB infection was already developed in late 1940s. It was 18.1% in male and 11.6% in female in Tokyo in late 1940s. Based on this concept, age specific TB mortality was analyzed by the type of TB, and the rates of miliary TB and TB meningitis were similar to the rate of newly infected to the total population, while the rate of all forms could be divided into early and late death as shown in Fig. 1. Fourth, I suffered from TB by myself from 1951 to 1953, receiving first thoracoplasty in two stages under local anaesthesia, then right upper lobectomy and segmentectomy of superior segment of right lower lobe. From this experience, I learnt a lot about the psychology and suffering of TB patients. Fifth, the importance of recognition of real magnitude of the problem in such a disease as TB in which many TB cases did not aware of their disease. The answer to this was the first TB prevalence survey in 1953 using stratified random sampling method, and based on the results of the survey, the mass health examination

  5. Fifty not out

    Science.gov (United States)

    2009-12-01

    What have the DESY laboratory in Germany, Richard Feynman's visionary lecture on nanotechnology, the discovery of the Aharonov-Bohm effect and the "two cultures" debate got in common? The answer is that they are all half a century old this year. The DESY lab was officially launched on 18 December 1959 and is marking its 50th anniversary with a series of events that included the official opening of the PETRA III synchrotron last month. Initially a particle-physics lab pure and simple, DESY is now changing its focus to accelerator science and is set to open its massive new 1bn European X-ray Free Electron Laser in 2014 (p12).

  6. DMT at fifty.

    Science.gov (United States)

    Szára, Stephen

    2007-12-01

    The steps taken for the discovery of the hallucinogenic effects of N.N-Dimethyl-tryptamine (DMT) is described. DMT had a difficult first 50 years in medical research primarily for legal reasons as it was classified as one of the "drugs of abuse" by authorities in the USA and by the World Health Organization. It has not proved to be a "schizotoxin" as it was first suspected, but the book is not closed on its potential role in some other, high level function as an endogenous neuromodulator. Further clinical work may even substantiate its usefulness in therapeutic application, such as an adjunct to psychotherapy, perhaps not by itself, but in a modified form, or in combination with other substances.

  7. Hydrology and Ecology of the Colorado River Delta in the Face of Changing Climate and Land Use Practices: the Next Fifty Years

    Science.gov (United States)

    Nagler, P. L.; Glenn, E. P.

    2007-12-01

    The Lower Colorado River Delta in the U.S. and Mexico is an internationally important aquatic biome, supporting fresh water and estuarine wetlands and a riparian corridor rich in avian and other wildlife. These rich ecosystems could be severely harmed by invasive species interacting with projected climate change and land use practices over the next 50 years. It is critical to measure land cover and monitor ecosystem and land use changes because these ecosystems are supported by fresh and brackish water flows originating from flood control releases and agricultural return flows in the U.S. and Mexico. Most climate models project a drying trend in the Colorado River watershed due to global warming, decreasing the frequency of flood releases to the Delta. Total basin water storage in the reservoir system is expected to be reduced by 32-40 percent, and flow volume is expected to meet demands in only 59-75 percent of years in 50 years. The frequency of spills (years in which water is released from the reservoirs to the Delta) will decrease under a global warming scenario. However, the Pacific Decadal Oscillation and ENSO events will continue to introduce variability into river flows, and there will still be years in which water is spilled to the Delta. Agricultural return flows will decrease as more water is diverted from agriculture to metropolitan use in both countries. The salinity of the ground water in Mexico, which currently supports cottonwood and willow trees in the riparian corridor, is increasing at a rate of about 20 ppm per year, and in 50 years it might be too saline for cottonwoods and willows. The riparian zone may become dominated by saltcedar and other salt-tolerant shrubs, degrading the habitat for birds and other wildlife. As flows to the Delta diminish, monitoring and active restoration projects to maintain trees and wetlands will be needed to preserve habitat value.

  8. Parity non-conservation in beta-decay of nuclei: revisiting experiment and theory fifty years after. IV. Parity breaking models

    CERN Document Server

    Georgiev, Mladen

    2008-01-01

    This part offers a survey of models proposed to cope with the symmetry-breaking challenge. Among them are the two-component neutrinos, the neutrino twins, the universal Fermi interaction, etc. Moreover, the broken discrete symmetries in physics are very much on the agenda and may occupy considerable time for LHC experiments next year aimed at revealing the symmetry-breaking mechanisms.

  9. Use of porous tantalum components in Paprosky two and three acetabular revision. A minimum five-year follow-up of fifty one hips.

    Science.gov (United States)

    Flecher, Xavier; Appy, Benjamin; Parratte, Sébastien; Ollivier, Matthieu; Argenson, Jean-Noel

    2017-05-01

    Recent studies have reported short-term favourable results of tantalum-made components in acetabular revisions with bone loss. However, there is a lack of information regarding the mid to long-term results of such components. The objective of this study was to analyse the outcome and survivorship of acetabular revision hip arthroplasty using tantalum components for loosening associated with bone loss at a minimum of five-year follow-up. We retrospectively reviewed 51 consecutive patients (51 hips) who had an acetabular revision using porous tantalum components at a minimum follow-up of five years. The mean age was 64 years (range, 31-87). There were 27 males and 24 females, 47 right hips and four left hips. Twenty-five (49 %) included a femoral revision. According to Paprosky's classification 18 hips were classified type 2A, 11 type 2B, ten type 2C, seven type 3A and five type 3B. No bone grafting was performed. Sixteen hips (31.3 %) required the use of additional tantalum-made augments stabilized by screws and cement at the cup-augment interface. At a mean followup of 6.8 years (range, 5.1-10 years), the Harris hip score improved from 44 pre- operatively (range, 23-72) to 84 post-operatively (range, 33-98). The mean post-operative hip centre position in relation to the teardrop was 29 mm (range, 20-43 mm) horizontally and 21 mm (range, 8-36 mm) vertically. The mean acetabular inclination was 42° (range, 17-60°). Six hips (11.7 %) required a re-operation without component revision (two for chronic instability, one ossification removal, one haematoma, one deep infection and one periprosthetic femoral fracture). One patient required a cup re-revision for septic loosening. No aseptic loosening occurred. At last followup the radiological analysis showed one evolutive osteolysis and one screw breakage. The global survivorship was 92.3 % at 64 months. If only aseptic loosening was defined as the end-point the survivorship was 100 % at 64 months. When

  10. 中国虫生真菌应用50年简史%Fifty years of application of entomogenous fungi in China

    Institute of Scientific and Technical Information of China (English)

    李增智

    2007-01-01

    In China, there is a long history over 2300 years of entomogenous fungi used as medicines,but their use against insect pests did not start until mid 1950′s.In 1970,the central government held a workshop to encourage the use of Beauveria bassiana against pine caterpillars,making the year a milestone in Chinese history of microbial pest control.Since then, quite a few fungi have been tried for control of over 60 forest and crop pests.In the past decades,low tech production has been being improved towards commercial production with higher techniques.Until 2006,5 products of fungal insecticides have been registered.Meanwhile,large scale application techniques have been being improved with molecular ecological approach towards a rational application strategy.

  11. The Relationship of Anterior Cruciate Ligament Lesions and Osteochondral Lesions with Meniscal Tears in Patients Younger than Fifty Years of Age

    Directory of Open Access Journals (Sweden)

    Samed Ordu

    2014-09-01

    Full Text Available Aim: The purpose of this study was to determine the incidence of anterior cruciate ligament (ACL lesions and osteochondral lesions according to type and localization of the meniscal tear and age, gender in patients who have been arthroscopicaly treated, besides, to make the coexisting lesions more predictable in these patients. Methods: We retrospectively investigated 352 patients under 50 years of age who underwent surgery for a meniscal tear between 2008 and 2012. We scanned the surgical operation notes, preoperative questionnaires and the magnetic resonance imaging findings. We recorded patients who had ACL lesions, such as elongation, partial rupture and total rupture. Osteochondral lesions were classified according to the Outerbridge classification from grade 1 to grade 4. Results: Chondral lesions were present in 77.4% of patients with degenerative meniscal tears and in 63% of patients with radial meniscal tears. One the other hand, osteochondral lesions were observed in only 33.9% of patients with other types of meniscal tears. 46.6% of ACL lesions accompanied by meniscal tears with longitudinal pattern, such as longitudinal tears, bucket handle tears and root tears. For the other types of meniscal tears, this percentage was 20.7. When we excluded degenerative type meniscal tears, the mean age of the patients with radial tears was 40.86±9.03 years and the mean age of the patients with other types of tear was 35.44±9.44 years. The difference was statistically significant. Conclusion: We found close relationship between osteoarthritic chondral lesions and radial tears in the root of the posterior horn of the medial meniscus. On the other side, longitudinal tears were related with ACL lesions. (The Me­di­cal Bul­le­tin of Ha­se­ki 2014; 52: 177-80

  12. Fifty-year follow-up of mortality among a cohort of iron-ore miners in Sweden, with specific reference to myocardial infarction mortality.

    Science.gov (United States)

    Björ, B; Burström, L; Jonsson, H; Nathanaelsson, L; Damber, L; Nilsson, T

    2009-04-01

    This study investigates both general mortality and mortality from myocardial infarction among men employed in iron-ore mines in Sweden. The mortality of employees (surface and underground workers) at the iron-ore mines in Malmberget and Kiruna, Sweden was investigated. The study cohort comprised men who had been employed for at least 1 year between 1923 and 1996. The causes of death were obtained from the national cause of death register from 1952 to 2001. Indirect standardised mortality ratios (SMR) were calculated for four main causes. Mortality specifically from myocardial infarction was also analysed. 4504 deaths in the cohort gave an SMR for total mortality of 1.05 (95% CI 1.02 to 1.09). Mortality was significantly higher for lung cancer (SMR 1.73, 95% CI 1.52 to 1.97). There was an increased risk of injuries and poisonings (SMR 1.34, 95% CI 1.24 to 1.46) and respiratory diseases (SMR 1.14, 95% CI 1.00 to 1.28). There were 1477 cases of myocardial infarction, resulting in an SMR of 1.12 (95% CI 1.07 to 1.18). SMR was higher (1.35, 95% CI 1.22 to 1.50) for men aged 60 years of age (1.06, 95% CI 1.00 to 1.13). Mortality from myocardial infarction was higher than expected. There was also an increased risk of death from injuries and poisonings, lung cancer and respiratory diseases, as well as higher general mortality. Our findings support the results of previous studies that there is an association between working in the mining industry and adverse health outcomes.

  13. Fifty years of changes in reef flat habitats of the Grand Récif of Toliara (SW Madagascar) and the impact of gleaning

    Science.gov (United States)

    Andréfouët, S.; Guillaume, M. M. M.; Delval, A.; Rasoamanendrika, F. M. A.; Blanchot, J.; Bruggemann, J. H.

    2013-09-01

    The Grand Récif of Toliara (GRT) in Madagascar is a large (33 km2) barrier reef system of the SW Indian Ocean that had been well investigated in the 1960s and early 1970s. A massive degradation of the reef has been reported since at least the early 1980s, just a few years after research activities ceased in the area. Examination of historical aerial photographs and modern high-resolution remote sensing images confirms a continuous loss of coral habitat on GRT outer reef flats between 1962 and 2011, with an average loss of 65 % and a range of 37-79 % loss during this 50-year period. The usual suspects of coral community declines (cyclones, bleaching and sedimentation) may have contributed to the demise of the GRT. However, an independent study (Salimo 1997) suggests that the chronic pressure of fisherman gleaning on reef flats with destructive tools is the main driver of the observed changes. Salimo's reported level of frequentation (6.8 fishermen per day and per km-2) and rates of destruction per fisherman (7.7 m2 of coral habitat h-1) yield a cumulated overall loss in agreement with the image-based rates of habitat loss. The GRT is unlikely to recover because this chronic stress is unlikely to decrease in the near future. Indeed, the GRT daily provides subsistence fishery resources for local Vezo people and to agriculturalist or pastoralist ethnic groups who have turned to exploiting coastal resources due to increasing aridity and dwindling agricultural and livestock production.

  14. The 1.3-m Robotically Controlled Telescope (RCT) at Kitt Peak - A Fifty year old dream Realized: Telescope Characteristics, Current Research and Education Progr

    Science.gov (United States)

    Guinan, Edward; Gelderman, Richard; Strolger, Louis-Gregory; Carini, Michael T.; McGruder, Charles, III; Campbell, Rachel; Walter, Donald K.; Davis, Donald R.; Tedesco, Edward F.; Engle, Scott G.

    2011-03-01

    The 1.3 m Robotically Controlled Telescope (RCT) on Kitt Peak has a rich history, including its role as a prototype for remotely controlled telescopes during the 1960s. As such, the RCT could be considered one of the first - Telescopes from Afar. The telescope, originally called the Remotely Controlled Telescope, has been renamed the Robotically Controlled Telescope to reflect the change in operational control and mode of use. The RCT was a conceptual precursor of today's robotic telescopes, but the actual operation of a remotely controlled telescope was technologically premature for its time, and was subsequently manually operated primarily to conduct optical and infrared observations as well being used as a test bed for new spectroscopic and photometric instruments. In 1995 budget constraints forced the closing of the telescope as part of the Kitt Peak National Observatory (KPNO), following nearly 30 years of distinguished service to KPNO. A request for proposals to operate this telescope was issued to the science community. The RCT consortium, lead by Western Kentucky University, was the successful proposer for operation of the telescope. After several difficult years of retrofitting, refurbishing, and automating the telecope and observatory dome, the telescope has returned to routine science operations in November 2009. The RCT has operated smoothly since that time, with no major interruptions. Observations of objects of interest to the consortium partners (including: comets & asteroids, variable & binary stars, exoplanets, supernovae, quasars & blazars) are being routinely obtained and evaluated. One of the distinguishing features of the RCT is that it is an autonomous observatory designed to handle diverse optical imaging and photometry programs. These include being able to automatically deal with a wide range of observing parameters such as -integration time, sky conditions, repetitions, return visits, filters, air mass, non-sidereal objects, transients etc

  15. Fifty years after the Nuremberg Nazi Doctors' Trial: reviewing how the laws of the Third Reich applied to individuals with oral clefts.

    Science.gov (United States)

    Wyszynski, D F

    1998-02-01

    The Nazi Doctors' Trial, held in the city of Nuremberg 50 years ago, is a landmark in the history of medicine and science. For the first time, the horrors inflicted by a group of German scientists on innocent victims became widely known. Most of the defendants received sentences that ranged from relatively short imprisonment to death. The Trial also provided elements to develop standards for permissible medical experimentation, known as the Nuremberg Code. The atrocities judged in the Nazi Doctors' Trial, however, were not isolated. They were part of an overall eugenic system that encouraged euthanasia, compulsory sterilization, and selective marriages based on "genetic health" and "racial hygiene." Individuals with oral clefts were considered subject to these laws and suffered their consequences. This paper describes the main features of the Trial, reviews the state of knowledge on oral clefts in the 1930s and 1940s, presents how the laws of the Third Reich impacted the lives of individuals with oral clefts, and speculates on the implications of past and present eugenic policies in the future of humankind.

  16. Long-term trends in sodium and chloride in the Mohawk River, New York: the effect of fifty years of road-salt application.

    Science.gov (United States)

    Godwin, K S; Hafner, S D; Buff, M F

    2003-01-01

    Ecological studies have demonstrated the adverse effects of road-salt, primarily NaCl, on water quality, flora, and fauna. In this study, we quantified changes in ionic composition and solute flux of water draining the Mohawk River Basin (9103 km(2)) in New York State, from 1952 to 1998. Using various statistical, graphical, and modeling techniques, we showed that concentrations ofNa+ and Cl- have increased by 130 and 243%, respectively, while other constituents have decreased or remained constant. The use of de-icing salt on roads within the watershed, which we estimate at 39 kg km(-2) day(-1), appears to be the primary mechanism responsible for reported increases, accounting for the increase in NaCl export from 16 to 46 kg km(-2) day(-1) over the 47-year period.Moreover, despite population decline within this rural upstate watershed, increased environmental stewardship, and The Clean Water Act, concentrations of Na+ and Cl- still increased during the 1990s.

  17. Adolescent Self-Organization and Adult Smoking and Drinking over Fifty Years of Follow-Up: The British 1946 Birth Cohort.

    Science.gov (United States)

    Nishida, Atsushi; Cadar, Dorina; Xu, Man K; Croudace, Timothy; Jones, Peter B; Kuh, Diana; Richards, Marcus

    2016-01-01

    Variations in markers of adolescent self-organization predict a range of economic and health-related outcomes in general population studies. Using a population-based birth cohort study we investigated associations between adolescent self-organization and two common factors over adulthood influencing health, smoking and alcohol consumption. The MRC National Survey of Health and Development (the British 1946 birth cohort) was used to test associations between a dimensional measure of adolescent self-organization derived from teacher ratings, and summary longitudinal measures of smoking and alcohol consumption over the ensuing five decades. Multinomial regression models were adjusted for sex, adolescent emotional and conduct problems, occupational social class of origin, childhood cognition, educational attainment and adult occupational social class. With all covariates adjusted, higher adolescent self-organization was associated with fewer smoking pack years, although not with quitting; there was no association with alcohol consumption across adulthood (none or heavy compared with light to moderate). Adolescent self-organization appears to be protective against smoking, but not against heavy alcohol consumption. Interpretation of this differential effect should be embedded in an understanding of the social and sociodemographic context in which these health behaviours occur over time.

  18. [Effects of fire recurrence on fire behaviour in cork oak woodlands (Quercus suber L.) and Mediterranean shrublands over the last fifty years].

    Science.gov (United States)

    Schaffhauser, Alice; Pimont, François; Curt, Thomas; Cassagne, Nathalie; Dupuy, Jean-Luc; Tatoni, Thierry

    2015-12-01

    Past fire recurrence impacts the vegetation structure, and it is consequently hypothesized to alter its future fire behaviour. We examined the fire behaviour in shrubland-forest mosaics of southeastern France, which were organized along a range of fire frequency (0 to 3-4 fires along the past 50 years) and had different time intervals between fires. The mosaic was dominated by Quercus suber L. and Erica-Cistus shrubland communities. We described the vegetation structure through measurements of tree height, base of tree crown or shrub layer, mean diameter, cover, plant water content and bulk density. We used the physical model Firetec to simulate the fire behaviour. Fire intensity, fire spread, plant water content and biomass loss varied significantly according to fire recurrence and vegetation structure, mainly linked to the time since the last fire, then the number of fires. These results confirm that past fire recurrence affects future fire behaviour, with multi-layered vegetation (particularly high shrublands) producing more intense fires, contrary to submature Quercus woodlands that have not burnt since 1959 and that are unlikely to reburn. Further simulations, with more vegetation scenes according to shrub and canopy covers, will complete this study in order to discuss the fire propagation risk in heterogeneous vegetation, particularly in the Mediterranean area, with a view to a local management of these ecosystems.

  19. An exponential growth of computational phantom research in radiation protection, imaging, and radiotherapy: a review of the fifty-year history.

    Science.gov (United States)

    Xu, X George

    2014-09-21

    Radiation dose calculation using models of the human anatomy has been a subject of great interest to radiation protection, medical imaging, and radiotherapy. However, early pioneers of this field did not foresee the exponential growth of research activity as observed today. This review article walks the reader through the history of the research and development in this field of study which started some 50 years ago. This review identifies a clear progression of computational phantom complexity which can be denoted by three distinct generations. The first generation of stylized phantoms, representing a grouping of less than dozen models, was initially developed in the 1960s at Oak Ridge National Laboratory to calculate internal doses from nuclear medicine procedures. Despite their anatomical simplicity, these computational phantoms were the best tools available at the time for internal/external dosimetry, image evaluation, and treatment dose evaluations. A second generation of a large number of voxelized phantoms arose rapidly in the late 1980s as a result of the increased availability of tomographic medical imaging and computers. Surprisingly, the last decade saw the emergence of the third generation of phantoms which are based on advanced geometries called boundary representation (BREP) in the form of Non-Uniform Rational B-Splines (NURBS) or polygonal meshes. This new class of phantoms now consists of over 287 models including those used for non-ionizing radiation applications. This review article aims to provide the reader with a general understanding of how the field of computational phantoms came about and the technical challenges it faced at different times. This goal is achieved by defining basic geometry modeling techniques and by analyzing selected phantoms in terms of geometrical features and dosimetric problems to be solved. The rich historical information is summarized in four tables that are aided by highlights in the text on how some of the most

  20. Fifty Years in the Technology of Acoustic Emission(1961--2011)%声发射技术五十年(1961-2011)

    Institute of Scientific and Technical Information of China (English)

    Allen T Green; 张磊

    2012-01-01

    This paper has a description of some of the Acoustic Emission projects that I have been involved with during the past 50 years. While my career in AE started with determining the residual strength of a glass and epoxy composite cylindrical pressure vessel it quickly expanded into many different materials, products and structures. In this paper I present information on efforts in; non-metallic and metallic pressure vessels; factors effecting AE; identification of modes of deformation; noise rejection methods; leak detection in Above Ground Storage Tanks; combining AE with UT; Acousto-Ultrasonic examination of wood particle boards; in-flight monitoring of Aircraft structure; and determination of water stress in grape plants and others.%文章对过去50年笔者所涉及的一些声发射项目做了回顾。笔者的声发射生涯是从检验玻璃环氧树脂圆柱形压力容器的剩余强度开始的,然后很快地延伸到了其它的很多材料、制品和结构中去。笔者在文中会介绍尽量多的信息,诸如:非金属和金属压力容器、影响声发射的因素、变型模式的识别、降噪技术、地上储罐泄漏探测、结合AE与UT、木材颗粒板的声-超声检验、飞行中飞机结构的监测以及葡萄科植物的缺水探测等。

  1. [Mercury and copper accumulation during last fifty years and their potential ecological risk assessment in sediment of mangrove wetland of Shenzhen, China].

    Science.gov (United States)

    Li, Rui-Li; Chai, Min-Wei; Qiu, Guo-Yu; He, Bei

    2012-12-01

    The processes of sediment transport and deposition can record some relative anthropogenic information in gulf region. Chronological analysis of the sediment core collected from mangrove wetland in Shenzhen Bay showed that the sedimentation rate was about 1.38 cm x a(-1). Soil buck density, pH, electrical conductivity (EC) and total organic carbon (TOC) changed in range of 0.36-0.71 g x cm(-3), 6-7, 2.93 x 10(3) -4.97 x 10(3) microS x cm(-1), and 1.5% - 3.8%, respectively. With the increase of soil depth, the soil buck density and EC increased gradually. However, the TOC decreased, with no significant change of pH. Contents of Hg and Cu in the whole depth of core ranged between 92-196 ng x g(-1) and 29-83 microg x g(-1), respectively. And both of them in sediment increased firstly and then decreased with the increasing soil depth. At 14 cm depth, contents of Hg and Cu reached up to the highest levels. Correspondingly, the ecological risk of Hg and Cu changed similarly with the contents of Hg and Cu. At 14 cm depth, the ecological risk indexes of Hg and Cu were at the highest levels of 39.10 and 13.85, respectively. The potential ecological risks of both Hg and Cu in sediments were mild. The rapid economical development of Hong Kong in 1960-1985 and Shenzhen in 1985-2000 contributed much to the Hg and Cu accumulation in mangrove wetland of Shenzhen Bay, China. Since the year of 2000, the reduction in contents of Hg and Cu has been expected as a consequence of the adoption of contamination control policies, improving the environment for growth of mangrove. In conclusion, the variations of core sediment heavy metal contents and its ecological risk assessment along the vertical profile reveal the interaction processes and extent of anthropogenic influences from the areas around the Shenzhen Bay and the catchments.

  2. Chemists in Rijeka Together for Fifty Years

    Directory of Open Access Journals (Sweden)

    Milin, C.

    2009-06-01

    Full Text Available Whatever part of the World you come from, when you come to Rijeka you came to the heart of Europe. Rijeka is waiting for you with the scent of its sea and the hospitality of its people. Rijeka is a town of unusual, turbulent and intersected history. At the end of the IX Century the area of Rijeka was one of the most powerful industrial zones in Europe. Prof. Eugen Cerkovnikov, Ph. D., a much-respected chemist, first Head of the Department for Chemistry and Biochemistry on the then newly established Medical School in Rijeka, launched the initiative to form a branch-office of the Croatian Chemist Society in Rijeka. On 18 January, 1958 in the Big Classroom of the Medical School in Rijeka the Founding Assembly was held, and many respected scientists of that period were present.In 1960, the Rijeka branch-office of the Croatian Chemist Society merged with the Society of Chemists and Technologists and in 1973 the Biochemists section joined. In the five decades of its existence, the love towards chemistry, biochemistry, molecular biology, technology and chemical engineering, the love towards the basis of natural sciences and the wish to educate new, progressive generations formed the mission of the Society. The Society does not want to be closed in a guild organisation; its aim is to open its doors towards all those striving to progress.Former presidents of the Society were: Eugen Cerkovnikov (1958-1974, Marijan Kolombo (1974-1980, Josip Šilipeter (1980-1984, Marinko Oršia (1984-1996 i Nikola Bla?evia (1996-; and each one of them marked his era. Transitional circumstances have shut down forever many, until recently, extremely powerful industries in Rijeka. Today, Rijeka is searching for new paths, and we believe that our Society will continue to work on and give its contribution to this search.

  3. Fifty Years of Discoveries in Nuclear Structure

    Science.gov (United States)

    Hamilton, J. H.; Ramayya, A. V.

    The complementary nature of the Vanderbilt experimental work and the theoretical work of the Frankfurt group on the rotation-vibration model, the generalized collective model, shape coexistence and cluster radioactivity is described. Recent discoveries in neutron-rich nuclei γ-vibrational bands compared with RVM and GCM are presented. Ultimate examples of cluster radioactivity in cold binary and ternary fission are discussed. Finally, we present evidence for the evolution from axial symmetry in 101Y to maximum triaxialilty in 113Rh and for chiral doublet bands in neutron-rich triaxial even-even nuclei between A=106 - 112.

  4. Military Aptitude Testing: The Past Fifty Years

    Science.gov (United States)

    1993-06-01

    Enhanced Computer-Administered Testing ECFA Examen Calificacion de Feurzas Armadas EST Enlistment Screening Test ETP Enlistment Testing Program GAO...qualification standards and in part on the needs of the Service. Qualification standards are more complex than just mental standards; they also include medical...and moral standards. Mental standards include educational level as well as aptitude test scores. The military testing program (MTP) began with the

  5. Fifty years of the renormalization group

    CERN Document Server

    Shirkov, D V

    2001-01-01

    Renormalization was the breakthrough that made quantum field theory respectable in the late 1940s. Since then, renormalization procedures, particularly the renormalization group method, have remained a touchstone for new theoretical developments. This work relates the history of the renormalization group. (17 refs).

  6. Thurstones's Discriminal Processes Fifty Years Later

    Science.gov (United States)

    Luce, R. Duncan

    1977-01-01

    Thurstone's landmark papers on psychophysics, published in the twenties, are discussed in this presidential address to the Psychometric Society. The development of psychophysics from Thurstone to the present is presented in some detail. (JKS)

  7. Energy Resources and the Next Fifty Years

    Science.gov (United States)

    Landon, S. M.

    2002-05-01

    At this time, approximately 85 percent of the energy needs of the United States are supplied by fossil fuels. Crude oil currently supports transportation, generally as gasoline or jet fuel. The United States is importing roughly 60 percent of the crude oil we are now using and our domestic refining capacity is declining. Coal is providing more than 56 percent of the nation's electricity, although the use of natural gas as a fuel for electricity generation has been increasing. Natural gas, with today's technology, is considered a cleaner fuel as we continue to move toward decarbonization. The next logical phase in this historical progress will probably be the transition to pure hydrogen as an energy source, chiefly as a fuel for fuel cells. The initial source of hydrogen will probably be natural gas, given the existing infrastructure for natural gas, its cost, and its availability. Demand for natural gas is expected to peak in approximately 2050. But in the transition to an affordable, efficient, reliable, market-driven, carbon-free energy economy, substantial demand will still exist for coal and crude oil, even as these energy fuels are phased out. A massive requirement will exist for natural gas as the transition fuel since renewables will probably continue to supply only about 10 percent of our nation's electricity demand. The implied demand for coal and oil in the U. S. and the World can readily be met with existing known or probable resources; the challenge will be in assuring supplies that are secure, priced reasonably, and made ever cleaner. The implied demand for natural gas, however, exceeds the currently estimated resource base both in the U. S. and globally. For example, the currently estimated remaining resource of natural gas in the U. S. is about 2,000 TCF. The implied demand for natural gas in a methane economy, during the transition to a non-fossil source of hydrogen, is on the order of 3,000 to 4,000 TCF, half again to twice currently estimated volumes, assuming likely population growth, average economic growth of 3 percent annually, average energy efficiency of 2 percent annually, and a contribution of natural gas of more than 50 percent of total energy used. Potential additions to the resource base are from such sources as basin-centered formations, coalbed methane, sub-volcanic reservoirs, methane hydrates, among others; but many of these sources are not well understood and the practicality and cost of their availability are not known.

  8. Fifty Years of Scholarship in Media Ethics

    Science.gov (United States)

    Christians, Clifford G.

    1977-01-01

    Describes changing attitudes toward the role of mass media ethics, as reflected in the literature. Available from: Journal of Communication, The Annenberg School of Communications, University of Pennsylvania, 3620 Walnut Street, Philadelphia, PA 19104, $15.00 yr; $4.00 sc. (KS)

  9. Medical sociology: a personal fifty year perspective.

    Science.gov (United States)

    Straus, R

    1999-06-01

    This paper reviews the author's experience in becoming a medical sociologist before the field had become formalized. The contributions to medical sociology of sociologist Selden D. Bacon and physician and medical educator William R. Willard are described. The relationship of medical sociology to medical behavioral science, as experienced at the University of Kentucky, is discussed. Finally, the thesis of the author's 1957 paper on the nature and status of medical sociology is re-examined.

  10. The Fifty Year Rehabilitation of the Egg

    Directory of Open Access Journals (Sweden)

    Donald J. McNamara

    2015-10-01

    Full Text Available The 1968 American Heart Association announced a dietary recommendation that all individuals consume less than 300 mg of dietary cholesterol per day and no more than three whole eggs per week. This recommendation has not only significantly impacted the dietary patterns of the population, but also resulted in the public limiting a highly nutritious and affordable source of high quality nutrients, including choline which was limited in the diets of most individuals. The egg industry addressed the egg issue with research documenting the minimal effect of egg intake on plasma lipoprotein levels, as well as research verifying the importance of egg nutrients in a variety of issues related to health promotion. In 2015 dietary cholesterol and egg restrictions have been dropped by most health promotion agencies worldwide and recommended to be dropped from the 2015 Dietary Guidelines for Americans.

  11. Impacts of Climate Change on Water Resources in Shaanxi Province During Past Fifty Years Based on Regression Models%基于评估模型的陕西省水资源气候影响分析

    Institute of Scientific and Technical Information of China (English)

    程肖侠; 孙娴; 方建刚; 毛明策; 梁奇琛

    2012-01-01

    利用陕西省1961—2009年96个观测站的年降水、气温资料以及1997—2006年水利部公布的水资源资料,基于线性拟合、水资源丰枯评价指标、变差系数及产水模数等方法和指标,对陕西省近50 a来的水资源状况进行了气候影响分析。结果表明,基于降水、气温的水资源评估模型能够对陕西省水资源状况进行评估,且评估效果好于只考虑降水的评估模型。近50 a来陕西省气候趋于暖干,年平均气温自20世纪90年代升高,1996年前后发生突变;年降水自20世纪80年代中后期减少,1988年前后发生突变。受气温升高,降水减少影响,近50 a来陕西省水资源量呈减少趋势,1991年前后发生突变,水资源量显著减少。20世纪90年代之前,陕西省水资源量正常偏多,之后水资源正常偏枯,且年际变化显著,年水资源量不稳定。陕西省属于旱年缺水类型,天然供水量的减少增加了水资源利用率,水资源供需压力增大。%Employing the annual mean precipitation and temperature data from 96 meteorological stations in Shaanxi Province during the period from 1961 to 2009,and the water resource data published by Chinese Ministry of Water Resources from 1997 to 2006,the impacts of climate change on water resources of Shaanxi Province were analyzed by linear regression,water resource evaluation index,variation coefficient,and water mode.The results show that,the water resource assessment model based on both precipitation and temperature data was more reasonable in evaluation than the one merely based on precipitation data.The climate had become warmer and drier in the past fifty years,the annual mean temperature increases substantially around 1996 and the annual precipitation decreases sharply around 1988.With the declining precipitation and increasing temperature,the water resources had gradually reduced in the past 50 years,and worsened around 1991.The water resources were more than enough

  12. 亚裔美国史学五十年:反思与展望%Fifty Years of Asian- American Historiography: Reflecting on the Past and Looking into the Future

    Institute of Scientific and Technical Information of China (English)

    王心扬

    2012-01-01

    This essay aims to examine the merits and problems of Asian -American historiography in the past 50 years. In the early days, a major problem in the field was an ideology -guided, monistic approach to academic research. By only focusing on racial discrimination and by deterring others from exploring Asian immigration history from different or additional perspectives, this approach dominated the field for nearly three decades at the cost of a fuller and more balanced picture of historical events. In recent years, however, there have emerged some new trends challenging the dogmatic approach to Asian - American studies. By examining the relationships between whites, blacks, and Asians as a triangulated relationship instead of a binary one, scholars writing since the mid - 1990s have refuted the traditional "black and white" theory on race relations in America. Meanwhile, those who explore Asian - American history from a transnational perspective have argued, persuasively, that Asian immigrants had dual nationalism and dual- cultural identities. In particular, they have discovered that Japanese immigration and Japanese expansionism were closely intertwined. Behind the decision to relocate the Japanese during World War II, "military necessity" did exist, ese new trends indicate that Asian- American historiography is headed toward maturity.%回顾和检讨亚裔美国史学在过去半个世纪里所走过的道路可以发现,早期亚裔美国史学中一个最突出的问题是以意识形态为主导的一元论历史观。在近30年的时间里,学者大都仅仅从“种族歧视”这一个角度去诠释历史事件,反对从其他视野去观察亚洲移民的经历。不过,最近15年来,这个领域中出现了冲破一元论历史观束缚的趋势。新一代学者提出了白人、黑人和亚裔之间三角形关系的论点,从而否定了“有色对白种”的双重种族关系理论模式。从“跨国主义”的视野观察

  13. 近50年来祁连山及河西走廊极端气温的季节变化特征%Seasonal Characteristics of Extreme Temperature Changes in Qilian Mountains and Hexi Corridor During Last Fifty Years

    Institute of Scientific and Technical Information of China (English)

    贾文雄

    2012-01-01

    Based on daily temperature data of 18 meteorological stations in Qilian Mountains and Hexi Corri- dor from 1960 to 2009, the seasonal characteristics of extreme temperature change were analyzed by methods of linear trend, Morlet wavelet and Mann-Kendall. The results indicate that extreme high temperature days in each season are on the rise significantly, especially increased with larger scales after the middle of 1980s. But that is contrary to extreme low temperature days, which decreased with larger scales after the middle of 1980s in spring and summer, and decreased after the middle and later of 1960s in autumn and winter. The changing scale of extreme temperature days is the largest in winter, and the changes of them are before ten years in win- ter than in other seasons, which indicated that the significant change of extreme temperature days took place in winter firstly. The cycle changes of extreme temperature days in different seasons are different, but they are grouped in 6-10 a, 12-16 a and 18-22 a. The major cycle of extreme high temperature days in spring, summer, autumn and winter are changing respectivelywith 8 a, 14 a, 16 a and 16 a, and that of extreme low temperature days are changing respectively with 14 a, 16 a, 14 a and 6 a. The mutation of extreme high temperature days in spring, summer, autumn and winter increased in 2002, 1997, 1994, 1986, respectively, but that of extreme low temperature days decreased in 2002, 1997, 1987, 1986, respectively. Except autumn, the abrupt changes of ex- treme high temperature days and extreme low temperature days in other seasons are coincident. The response to global warming of extreme temperature days is earlier in autumn and winter than that in spring and summer. The change of extreme temperature days will bring some effect to the Qilian Mountains and Hexi Corridor. The increase of extreme high temperature days will add pressure of preventing fire for forest and grasslands in Qilian Mountains. The decrease of

  14. The Progresses of Seaport City Studies in the Last Fifty Years%20世纪60年代以来海港城市研究进展

    Institute of Scientific and Technical Information of China (English)

    王海壮; 栾维新

    2011-01-01

    As a special urban type,seaport cities have aroused wide concern from academic communities at home and abroad since the 1960s.Nowadays,there are plenty of academic outputs in this field,which are classi-fied into several research topics such as port-city relationship,port development and evolution,integrated plan-ning of port and city,and spatial structure of port cities.Although several scholars reviewed some subjects in this field recently,there is not a complete literature review of seaport city studies.This paper collected academic works related in recent more than 50 years,sorted them out in term of study topics firstly,and then summed up,analyzed and compared these subjects to show the research context and to find study shortages and future direc-tions in this field.After reviewing,we can draw the following conclusions.Firstly,the attention to seaport cities is increasing worldwide,but it lacks coherence at home.Secondly,research perspective has transferred from port-city evolution to port-city relationship,but the latter is relatively confined at home.Thirdly,the study meth-od has changed from qualitative to quantitative analysis,but still lacks interdisciplinary approach.Fourthly,spa-tial analysis is an essential method all the time,and scale and indicators shall be supplemented in the future study.Finally,there are many studies in this field that focus on evolution process and status of seaport cities,but there are relatively few studies on theories and their applications to newly built seaport cities.%作为一种特殊的城市类型,海港城市自20世纪60年代开始就受到国内外学术界的广泛关注,如今已有较为丰富的学术产出,可大体划归为港城关系、港口地域演化、港城一体规划和港城空间结构等研究主题,尽管前人曾对某一方面的研究进展作过评述性的工作,但仍缺乏比较系统全面的海港城市研究综述。本文搜集半个多世纪的国内外相关文献,根据研究主

  15. Fifty challenging problems in probability with solutions

    CERN Document Server

    Mosteller, Frederick

    1987-01-01

    Can you solve the problem of ""The Unfair Subway""? Marvin gets off work at random times between 3 and 5 p.m. His mother lives uptown, his girlfriend downtown. He takes the first subway that comes in either direction and eats dinner with the one he is delivered to. His mother complains that he never comes to see her, but he says she has a 50-50 chance. He has had dinner with her twice in the last 20 working days. Explain. Marvin's adventures in probability are one of the fifty intriguing puzzles that illustrate both elementary ad advanced aspects of probability, each problem designed to chall

  16. Fifty years of fiscal planning and implementation in the Netherlands

    NARCIS (Netherlands)

    Beetsma, R.; Giuliodori, M.; Walschot, M.; Wierts, P.

    2010-01-01

    Using real-time data from the annual budget over the period 1958-2009, we explore the planning and realization of fiscal policy in the Netherlands. Our key findings are the following. First, planned surpluses are on average unbiased, although they are overoptimistic during the first half of the samp

  17. The lure of local SETI: Fifty years of field experiments

    Science.gov (United States)

    Ailleris, Philippe

    2011-01-01

    With the commemoration in October 2007 of the Sputnik launch, space exploration celebrated its 50th anniversary. Despite impressive technological and scientific achievements the fascination for space has weakened during the last decades. One contributing factor has been the gradual disappearance of mankind's hope of discovering extraterrestrial life within its close neighbourhood. In striking contrast and since the middle of the 20th century, a non-negligible proportion of the population have already concluded that intelligent beings from other worlds do exist and visit Earth through space vehicles popularly called Unidentified Flying Objects (UFOs). In light of the continuous public interest for the UFO enigma symbolized by the recent widely diffused media announcements on the release of French and English governmental files; and considering the approach of broadening the strategies of the "Active SETI" approach and the existence of a rich multi-disciplinary UFO documentation of potential interest for SETI; this paper describes some past scientific attempts to demonstrate the physical reality of the phenomena and potentially the presence on Earth of probes of extraterrestrial origin. Details of the different instrumented field studies deployed by scientists and organizations during the period 1950-1990 in the USA, Canada and Europe are provided. In conclusion it will be argued that while continuing the current radio/optical SETI searches, there is the necessity to maintain sustaining attention to the topic of anomalous aerospace phenomena and to develop new rigorous research approaches.

  18. Fifty-one years of Los Alamos Spacecraft

    Energy Technology Data Exchange (ETDEWEB)

    Fenimore, Edward E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-09-04

    From 1963 to 2014, the Los Alamos National Laboratory was involved in at least 233 spacecraft. There are probably only one or two institutions in the world that have been involved in so many spacecraft. Los Alamos space exploration started with the Vela satellites for nuclear test detection, but soon expanded to ionospheric research (mostly barium releases), radioisotope thermoelectric generators, solar physics, solar wind, magnetospheres, astrophysics, national security, planetary physics, earth resources, radio propagation in the ionosphere, and cubesats. Here, we present a list of the spacecraft, their purpose, and their launch dates for use during RocketFest

  19. 50 (Fifty) Years of Research on Man in Flight

    Science.gov (United States)

    1985-06-01

    authorized a Vito Commander position in March 1972. Colonel Dt-)pelt was appointed the first Vice Commander of the Laboratory. Colonel D oppelt wa-is...Clauser, 7184, 1972) " Development of the Systems Analysis Integrated Network ot Tasks ( SAINT ). First man system model for predicting nuclear S V effects

  20. Fifty Years of IMF Variation: The Intermediate-Mass Stars

    CERN Document Server

    Scalo, J

    2004-01-01

    I track the history of star count estimates of the Milky Way field star and open cluster IMFs, concentrating on the neglected mass range from 1 to 15 M${_\\odot}$. The prevalent belief in a universal IMF appears to be without basis for this mass range. Two recent estimates of the field star IMF using different methods and samples give values of the average logarithmic slope $\\Gamma$ between -1.7 and -2.1 in the mass range 1.1 to 4 M${_\\odot}$. Two older estimates between 2 and 15 M${_\\odot}$ disagree severely; the field IMF in this range is essentially unknown from star counts. Variations in $\\Gamma$ among open cluster IMFs in this mass range have not decreased despite numerous detailed studies, even for studies using homogeneous data and reduction procedures and including only clusters with a significant mass range. These cluster variations \\textit{might} be due to the combined effects of sampling, systematic errors, stellar evolution uncertainties, dynamical evolution, and unresolved binaries. If so, then th...

  1. Fifty years later: A neurodynamic explanation of Fitts' law.

    Science.gov (United States)

    Beamish, Dan; Bhatti, Shabana Ali; MacKenzie, I Scott; Wu, Jianhong

    2006-10-22

    An intrinsic property of human motor behaviour is a trade-off between speed and accuracy. This is classically described by Fitts' law, a model derived by assuming the human body has a limited capacity to transmit information in organizing motor behaviour. Here, we propose an alternative foundation, based on the neurodynamics of the motor circuit, wherein Fitts' law is an approximation to a more general relationship. In this formulation, widely observed inconsistencies with experimental data are a consequence of psychomotor delay. The methodology developed additionally provides a method to estimate the delay within the motor circuit from the speed-accuracy trade-off alone.

  2. The Laser: fifty years already; Le Laser: deja cinquante ans

    Energy Technology Data Exchange (ETDEWEB)

    Pocholle, J.P. [Thales Research and Technology, 91 - Palaiseau (France)

    2010-09-15

    The fiftieth anniversary celebration has this characteristic which it makes it possible to carry a retrospective glance on the evolution of a subject. From this point of view, the LASER, as a scientific concept or a technological tool, does not escape the rule. This article recalls the historical contributions leading to the first demonstration of the laser effect by Theodore Maiman in 1960, starting from a theoretical concept established by Albert Einstein in 1917. This demonstration naturally opened a strong activity in the laboratories. It resulted in the creation of instruments which took part in the enrichment of knowledge in the fields of physics, chemistry and the biomedical one. In our daily life, the communications, the information storage, the imagery, lighting and the industrial tools profited from the properties of the coherent or quasi-coherent emission of the light. Each one of these applications to follow-up its own evolutions which we will also try to describe in this article. (author)

  3. Fifty years of crop protection, 1950-2000

    NARCIS (Netherlands)

    Zadoks, J.C.

    2002-01-01

    We detected the presence of fructosamine in human and bovine semen. In seminal plasma of healthy normozoospermic men (N = 17) fructosamine was found in 53% of the cases (fru+). In fru+ semen samples the concentration of fructosamine was (mean ± S.E.M., N = 9) 0.45 ± 0.09 mmol/L and varied from 0.15

  4. Ion Channels, from Fantasy to Fact in Fifty Years1

    Science.gov (United States)

    Jordan, Peter C.

    Biologists have long recognized that the transport of ions and of neutral species across cell membranes is central to physiological function. Cells rely on their biomembranes, which separate the cytoplasm from the extracellular medium, to maintain the two electrolytes at very different composition. Specialized molecules, essentially biological nanodevices, have evolved to selectively control the movement of all the major physiological species. As should be clear, there have to be at least two distinct modes of transport. To maintain the disequilibrium, there must be molecular assemblies that drive ions and other permeable species against their electrochemical potential gradients. Such devices require energy input, typically coupling a vectorial pump with a chemical reaction, the dephosphorylation of ATP (adenosine triphosphate). These enzymes (biochemical catalysts) control highly concerted, and relatively slow, process, with turnovers of ≫ 100 s¡ 1.

  5. Recent nonmetropolitan population change in fifty-year perspective.

    Science.gov (United States)

    Johnson, K M; Purdy, R L

    1980-02-01

    Post-1970 nonmetropolitan population shifts are examined by dividing nonmetropolitan counties into ten cohorts based on the duration and direction of consistent population change since 1920. Analysis indicates that the post-1970 gains reported by Beale are pervasive in nonmetropolitan America, occurring even in a majority of the counties that lost population consistently from 1920 to 1970. Growth was greatest in countries adjacent to metropolitan areas but was more than urban spillover effect. In a clear break with traditional patterns, net inmigration contributed significantly to overall population gain and was particularly strong among countries without an urban center. The rate of natural increase continued to slow in the post-1970 period, with natural decrease becoming common among countries with protracted histories of population decline.

  6. Beyond the Ionosphere: Fifty Years of Satellite Communication

    Science.gov (United States)

    Butrica, Andrew J. (Editor)

    1997-01-01

    The three overlapping stages of satellite communications development outlined provide the three-part framework for the organization of the papers contained in this book. Part 1, 'Passive Origins,' treats the first stage of satellite communications development, extending from the 1940s into the early 1960s, when passive artificial and natural satellites funded by the military and private enterprise established the field. Part 2, 'Creating the Global, Regional, and National Systems,' addresses events that constituted the second stage of development. Early in this stage, which stretched from the 1960s into the 1970s, satellite systems began to make their appearance in the United States, while domestic and international efforts sought to bring order to this new but chaotic, field in the form of Comsat and Intelsat. Part 3, 'The Unfolding of the World System,' explores the development of satellite communications in the remainder of the world, with a strong emphasis on Asia.

  7. Hashing in computer science fifty years of slicing and dicing

    CERN Document Server

    Konheim, Alan G

    2009-01-01

    Written by one of the developers of the technology, Hashing is both a historical document on the development of hashing and an analysis of the applications of hashing in a society increasingly concerned with security. The material in this book is based on courses taught by the author, and key points are reinforced in sample problems and an accompanying instructor s manual. Graduate students and researchers in mathematics, cryptography, and security will benefit from this overview of hashing and the complicated mathematics that it requires

  8. Fifty years of nuclear fission: Nuclear data and measurements series

    Energy Technology Data Exchange (ETDEWEB)

    Lynn, J.E.

    1989-06-01

    This report is the written version of a colloquium first presented at Argonne National Laboratory in January 1989. The paper begins with an historical preamble about the events leading to the discovery of nuclear fission. This leads naturally to an account of early results and understanding of the fission phenomena. Some of the key concepts in the development of fission theory are then discussed. The main theme of this discussion is the topography of the fission barrier, in which the interplay of the liquid-drop model and nucleon shell effects lead to a wide range of fascinating phenomena encompassing metastable isomers, intermediate-structure effects in fission cross-sections, and large changes in fission product properties. It is shown how study of these changing effects and theoretical calculations of the potential energy of the deformed nucleus have led to broad qualitative understanding of the nature of the fission process. 54 refs., 35 figs.

  9. Fifty years of oxacalix[3]arenes: A review

    Directory of Open Access Journals (Sweden)

    Kevin Cottet

    2012-02-01

    Full Text Available Hexahomotrioxacalix[3]arenes, commonly called oxacalix[3]arenes, were first reported in 1962. Since then, their chemistry has been expanded to include numerous derivatives and complexes. This review describes the syntheses of the parent compounds, their derivatives, and their complexation behaviour towards cations. Extraction data are presented, as are crystal structures of the macrocycles and their complexes with guest species. Applications in fields as diverse as ion selective electrode modifiers, fluorescence sensors, fullerene separations and biomimetic chemistry are described.

  10. Fifty years of illumination about the natural levels of adaptation

    DEFF Research Database (Denmark)

    Boomsma, Jacobus Jan

    2016-01-01

    A visionary Darwinian ahead of his time, George C. Williams developed in his 1966 book Adaptation and Natural Selection the essentials of a unifying theory of adaptation that remains robust today and has inspired immense progress in understanding how natural selection works....

  11. Fifty years of CFD for room air distribution

    DEFF Research Database (Denmark)

    Nielsen, Peter Vilhelm

    2015-01-01

    , and to addressing situations with more steady-state solutions. The article finishes with a number of different case studies such as design of air supply openings, smoke management in buildings, cross-infection risks from the exhalation of particles and calculation of people moving in a room. The use of benchmark...

  12. Fifty-year study of the Peierls-Nabarro stress

    CSIR Research Space (South Africa)

    Nabarro, FRN

    1997-08-30

    Full Text Available The origin of the Peierls model and its relation to that of Frenkel and Kontorova are described. Within this model there are three essentially different formulae for the stress required to move a dislocation rigidly through a perfect lattice...

  13. Fifty years of Szigeti's dielectric theory – A review

    Indian Academy of Sciences (India)

    D B Sirdeshmukh; L Sirdeshmukh; K G Subhadra

    2007-10-01

    During the period 1949–1961 Szigeti published four seminal papers on the dielectric behaviour of crystals. Szigeti's theory is applicable to isotropic and anisotropic, ionic and covalent crystals with different structures. Szigeti's theory connects dielectric, spectroscopic and elastic properties. An important outcome of Szigeti's theory is the concept of the effective ionic charge (). It is pointed out that correlates with a number of physical properties and is a measure of ionicity of the interatomic bond. Since Szigeti's work, several theoretical models have been proposed to account for the fact that < 1. These models provide an insight into the complex polarization mechanisms in solids. This review summarizes Szigeti's work and the work that followed; the implications and applications of Szigeti's theory are discussed. Some new results are also included.

  14. Fifty years of fiscal planning and implementation in the Netherlands

    NARCIS (Netherlands)

    Beetsma, R.; Giuliodori, M.; Walschot, M.; Wierts, P.

    2012-01-01

    Using real-time data from the annual budgets over the period 1958-2009, we explore budgetary planning and implementation in the Netherlands. Three fiscal policy regimes are distinguished. Our key findings are the following. First, plans are on average unbiased, although they are overoptimistic durin

  15. Fifty years of fiscal planning and implementation in the Netherlands

    NARCIS (Netherlands)

    Beetsma, R.; Giuliodori, M.; Walschot, M.; Wierts, P.

    2013-01-01

    Using real-time data from the annual budgets over the period 1958-2009, we explore budgetary planning and implementation in the Netherlands. Three fiscal policy regimes are distinguished. Our key findings are the following. First, plans are on average unbiased, although they are overoptimistic durin

  16. The Journal of The Experimental Analysis of Behavior at Fifty

    Science.gov (United States)

    Laties, Victor G

    2008-01-01

    The Journal of the Experimental Analysis of Behavior was founded in 1958 by a group of male psychologists, mainly from the northeastern USA and connected with either Harvard or Columbia. Fifty years later about 20% of both editors and authors reside outside this country and almost the same proportion is made up of women. Other changes in the journal include having its own website for more than a decade and now publishing online as well as on paper. A recent connection with PubMed Central of the National Library of Medicine has made possible the completely free electronic presentation of the entire archive of about 3,800 articles. PMID:18338677

  17. Fifty shades of exploitation: Fan labor and Fifty Shades of Grey

    Directory of Open Access Journals (Sweden)

    Bethan Jones

    2014-03-01

    Full Text Available This exploration of the debates that have taken place in fandom over the ethics of pulling fan fiction and publishing it as original work draws on the notion of the fannish gift economy, which postulates that gifts such as fan fiction and fan art have value in the fannish community because they are designed to create and cement its social structure. Tension exists between fans who subscribe to the notion of a fannish gift economy and those who exploit fandom by using it to sell their pulled-to-publish works. An examination of E. L. James's 2012 Fifty Shades trilogy (comprising the books Fifty Shades of Grey, Fifty Shades Darker, and Fifty Shades Freed, which began as Twilight fan fiction, in addition to Twilight fan art sold through sites such as Redbubble and Etsy, demonstrates a tension between the two modes of fan expression: sale of artworks appears to be an acceptable practice in fandom, but the commercial sale of fan fic, even when marketed as original fiction, is widely contested.

  18. Nuclear histochemistry: Its history in fifty volumes

    Directory of Open Access Journals (Sweden)

    M.G. Manfredi Romanini

    2014-01-01

    Full Text Available The fiftieth anniversary of the double helix was marked two years ago. The elucidation of the structure of DNA by Watson and Crick can rightfully be considered to be "the" milestone in modern biology because it has conditioned the explosive growth in our understanding of the molecular mechanisms regulating the structural and functional organization of single cells and multicellular organisms....

  19. 55岁以下成年移位股骨颈骨折内固定术后失败的研究分析%Failure of internal fixation on displaced femoral neck fractures in adults under fifty-five years old

    Institute of Scientific and Technical Information of China (English)

    俞银贤; 马金忠; 朱力波; 陆海明; 桑伟林

    2012-01-01

    目的:回顾性研究年龄55岁以下成年患者移位股骨颈骨折内固定治疗失败病例以提高对其治疗的重视.方法:2007年1月至2010年6月治疗55岁以下移位股骨颈骨折内固定术后失败患者18例,男13例,女5例;年龄27~55岁,平均(48.0±6.0)岁;空心钉治疗17例,髓内钉治疗1例.入院时诊断为股骨头坏死16例,骨不连合并股骨头坏死2例.结果:18例患者内固定术后至手术失败时间8~32个月,平均23个月.复位内固定术后Garden指数不佳;入院时髋关节Harris评分33~80分,平均(56.0±12.5)分.8例股骨头坏死病例和2例骨不连合并股骨头坏死病例接受了全髋关节置换术,5例股骨头坏死病例接受了表面髋关节置换术,3例虽然影像学有股骨头坏死征象但临床症状不明显,接受了保守治疗.所有行髋关节表面置换和全髋关节置换的病例术后随访12~53个月,平均34个月,术后Harris评分(94.0±3.0)分(89~96分).结论:股骨头坏死是55岁以下成年移位股骨颈骨折闭合复位内固定术后常见并发症,必须提高对青壮年股骨颈骨折闭合复位内固定治疗的重视.%Objective:To investigate the failure of internal fixation on displaced femoral neck fractures in adults under fifty-five years old retrospectively inorder to pay more attention to the treatment of these fractures. Methods: From Junary 2007 to June 2010,18 failed cases of internal fixation on displaced femoral neck fractures in adults under fifty-five years old were treated,there were 13 males and 5 females with an average age of (48.0±6.0) years old ranging from 27 to 55. Among them, 17 patients were treated with cannulated screws and ) patient was treated with intramedullaiy nail; 16 patients were diagnosed as osteonecrosis and 2 patients as osteonecrosis associated with nonunion. Results:The average time from internal fixation to failure was 23 months (ranged, 8 to 32 months). The quality of fracture reduction in

  20. The "Journal of the Experimental Analysis of Behavior" at Zero, Fifty, and One Hundred

    Science.gov (United States)

    Catania, A. Charles

    2008-01-01

    The experimental content areas represented in "JEAB" in its first volume (1958) and fifty 50 years later in Volume 87 are in many ways similar with regard to research on schedules of reinforcement, research with human subjects, and several other topics. Experimental analysis has not been displaced by quantitative analysis. Much less research on…

  1. Women's Heart Disease: Cindy Parsons and Follow the Fifty

    Science.gov (United States)

    ... this page please turn JavaScript on. Feature: Women's Heart Disease Cindy Parsons and Follow the Fifty Past Issues / ... Program, knowing that her personal risk factors for heart disease, including family history, were high. She watched her ...

  2. Transformationer i mediekulturen - Fifty Shades som fanfænomen

    OpenAIRE

    Matthiasen, Anja Falkner; Barding, Antonia; Eliasen, Kristina Maria Danielsen

    2015-01-01

    This project examines the Fifty Shades phenomenon where fan cultures and community building surrounding this particular universe are a few of the keywords to understanding this said phenomenon. Through Henry Jenkins’ transmedia storytelling and worldbuilding theory and Donald Horton & Richard Wohl’s theory on parasocial interactions as well as John B. Thompson’s non-reciprocal relation theory it can be concluded that the fans are what’s keeping the Fifty Shades universe alive and still rapidl...

  3. Sexist Attitudes Among Emerging Adult Women Readers of Fifty Shades Fiction.

    Science.gov (United States)

    Altenburger, Lauren E; Carotta, Christin L; Bonomi, Amy E; Snyder, Anastasia

    2017-02-01

    Stereotypical sexist representations of men and women in popular culture reinforce rigid views of masculinity (e.g., males as being strong, in control, masterful, and aggressive) and femininity (e.g., women as being fragile and weak, unassertive, peaceful, irrational, and driven by emotions). The present study examined associations between the fictional series Fifty Shades-one popular culture mechanism that includes pervasive traditional gender role representations-and underlying sexist beliefs among a sample of 715 women ages 18-24 years. Analyses revealed associations between Fifty Shades readership and sexism, as measured through the Ambivalent Sexism Inventory. Namely women who reported reading Fifty Shades had higher levels of ambivalent, benevolent, and hostile sexism. Further, those who interpreted Fifty Shades as "romantic" had higher levels of ambivalent and benevolent sexism. Our findings support prior empirical studies noting associations between interacting with aspects of popular culture, such as television and video games, and individual beliefs and behaviors.

  4. Carpal tunnel syndrome - electrodiagnostic aspects of fifty seven symptomatic hands.

    OpenAIRE

    1999-01-01

    Electrodiagnostic data of fifty seven symptomatic extremities with carpal tunnel syndrome (CTS) are described. Practice recommendations made by American Academy of Neurology, American Association of Electrodiagnostic Medicine and American Academy of Physical Medicine and Rehabilitation regarding electrodiagnostic studies were considered while confirming CTS diagnosis by electrodiagnostic studies. Median sensory nerve conduction studies were the commonest abnormalities noted. The median orthod...

  5. 1977 flywheel technology symposium proceedings. [Fifty-two papers

    Energy Technology Data Exchange (ETDEWEB)

    Chang, G.C.; Stone, R.G. (eds.)

    1978-03-01

    Fifty-two papers, four paper abstracts, and four brief summaries of panel discussions are presented on flywheel energy storage technology. A separate abstract was prepared for each of 41 papers for inclusion in DOE Energy Research Abstracts (ERA). Eleven papers were processed previously for inclusion in the data base. (PMA)

  6. Mathematical card magic fifty-two new effects

    CERN Document Server

    Mulcahy, Colm

    2013-01-01

    Mathematical card effects offer both beginning and experienced magicians an opportunity to entertain with a minimum of props. Featuring mostly original creations, Mathematical Card Magic: Fifty-Two New Effects presents an entertaining look at new mathematically based card tricks. Each chapter contains four card effects, generally starting with simple applications of a particular mathematical principle and ending with more complex ones. Practice a handful of the introductory effects and, in no time, you'll establish your reputation as a ""mathemagician."" Delve a little deeper into each chapter

  7. From 2000 Bush-Gore to 2006 Italian elections: Voting at fifty-fifty and the Contrarian Effect

    CERN Document Server

    Galam, S

    2007-01-01

    A sociophysical model for opinion dynamics is shown to embody a series of recent western hung national votes all set at the unexpected and very improbable edge of a fifty-fifty score. It started with the Bush-Gore 2000 American presidential election, followed by the 2002 Stoiber-Schr\\H{o}der, then the 2005 Schr\\H{o}der-Merkel German elections, and finally the 2006 Prodi-Berlusconi Italian elections. In each case, the country was facing drastic choices, the running competing parties were advocating very different programs and millions of voters were involved. Moreover, polls were given a substantial margin for the predicted winner. While all these events were perceived as accidental and isolated, our model suggests that indeed they are deterministic and obey to one single universal phenomena associated to the effect of contrarian behavior on the dynamics of opinion forming. The not hung Bush-Kerry 2005 presidential election is shown to belong to the same universal frame. To conclude, the existence of contraria...

  8. Carpal tunnel syndrome - electrodiagnostic aspects of fifty seven symptomatic hands.

    Directory of Open Access Journals (Sweden)

    Murthy J

    1999-10-01

    Full Text Available Electrodiagnostic data of fifty seven symptomatic extremities with carpal tunnel syndrome (CTS are described. Practice recommendations made by American Academy of Neurology, American Association of Electrodiagnostic Medicine and American Academy of Physical Medicine and Rehabilitation regarding electrodiagnostic studies were considered while confirming CTS diagnosis by electrodiagnostic studies. Median sensory nerve conduction studies were the commonest abnormalities noted. The median orthodromic sensory latencies were prolonged in 86% and sensory nerve action potential amplitude abnormalities were seen in 82%. Prolongation of the conduction in the short segment across the wrist in the median nerve was seen in 96.5% and the difference in the conduction between median and ulnar nerve across the wrist was significant in all the 57 extremities. The median motor latencies were prolonged in 67% of hands. Higher incidence of electrodiagnostic abnormalities observed in this study might be due to inclusion of patients with severe disease.

  9. The decision book fifty models for strategic thinking

    CERN Document Server

    Krogerus, Mikael

    2011-01-01

    Most of us face the same questions every day: What do I want? And how can I get it? How can I live more happily and work more efficiently? A worldwide bestseller, The Decision Book distils into a single volume the fifty best decision-making models used on MBA courses and elsewhere that will help you tackle these important questions - from the well known (the Eisenhower matrix for time management) to the less familiar but equally useful (the Swiss Cheese model). It will even show you how to remember everything you will have learned by the end of it. Stylish and compact, this little black book is a powerful asset. Whether you need to plot a presentation, assess someone's business idea or get to know yourself better, this unique guide will help you simplify any problem and take steps towards the right decision.

  10. EUPHEMISTIC AND DYSPHEMISTIC LANGUAGE IN FIFTY SHADES OF GREY TRILOGY

    Directory of Open Access Journals (Sweden)

    Raquel Sánchez Ruiz

    2015-01-01

    Full Text Available The popularity of Fifty Shades of Grey trilogy is beyond doubt. This great impact has also been reflected on academic literature dealing with the novel from different perspectives. However, while there is substantial research on the novels, little attention has been paid to the author's usage of language. Bearing in mind that erotic stories are a common euphemistic and dysphemistic ground, the aim of this paper is to explore euphemism, dysphemism and x-phemism (quasieuphemism and quasidysphemism in a corpus which consists of the three books of the mentioned trilogy so as to observe if the use of these devices depends on sexes and how these phenomena merge with metaphorical or metonymical devices to avoid a possible loss of face or highlight a taboo. The conclusions will show that the male and female main characters in the novels use language differently and employ these verbal devices with several intentions.

  11. TREATMENT OF CHRONIC BRONCHITIS WITH FIFTY-YING-ACUPUNCTURE THERAPY

    Institute of Scientific and Technical Information of China (English)

    袁民

    2001-01-01

    Objective: To observe the clinical effect of Fifty-ying acupuncture therapy for treatment of chronic bronchitis, and to explore its underlying mechanisms. Methods: A total of 36 out- and in-patients with chronic bronchitis including 10 cases of asthma were subjected into this study. Among them, 20 cases were qi-deficiency type and 16 qi-yin-deficiency with phlegm-clamp type. The changes of symptoms, T-lymphocyte subgroups of CD3+, CD4+, CD8+,CD4+/CD8+, soluble interleuki-2 receptor ( SIL-2R), interleukin-6(IL-6), IgG, IgA and IgM before and after treatment were observed and detected using monoclonal indirect fluorescence method, enzyme linked immunosorbent assay (ELISA) and nephelometry respectively. Results: (1)The effective rate of qi-dificiency type was 100% and that of qi-yin-deficiency with phlegm-damp type 87.5%. (2) After acupuncture treatment, in qi-deficiency type patients, serum IgG, IgA and IgM contents increased significantly (P< 0. 001) in comparison with pre-treatment and in qi-yin-deficiency with phlegm-damp type patients, IgG level lowered obviously. Serum SIL-2R and CD4+/CD8+ decreased obviously(P<0.01, 0.001), CD3+, CD4+ and CD8+ increased evidently (P<0.01). Conclusion: The Fifty-ying acupuncture therapy can better clinical symptoms of chronic bronchitis patients through its resultant up-regulation of the immune system function.

  12. The Journal of the Experimental Analysis of Behavior at fifty

    National Research Council Canada - National Science Library

    Laties, Victor G

    2008-01-01

    ...: behavior analysis history, women as journal editors, geographical distribution of editors, online publishing, B.F. Skinner I have lived my professional life by decades. It was 60 years ago, in 1928, that I arrived at Harvard as a graduate student in psychology. Behaviorism was then only 15 years old. Ten years later, in 1938, I published The Behav...

  13. Temporal and spatial change of climate extremes in Qilian Mountains and Hexi Corridor during last fifty years%近50a来祁连山及河西走廊极端气候的时空变化研究

    Institute of Scientific and Technical Information of China (English)

    贾文雄

    2012-01-01

    Under the condition of global warming, the frequency of extreme climate and damage of meteorological disasters are increasing. Based on daily temperature and precipitation data of 20 weather stations in the Qilian Mountains and Hexi Corridor from 1960 to 2009, the inter-annual change trends of climate extremes were studied by methods of regression analysis and five years moving average, and the spatial distribution characteristics of inter-annual change trends and its significance of climate extremes were analyzed by method of Spline interpolation under ArcGIS environment, and the cycles of climate extremes were discussed by method of Morlet wavelet analysis under Matlab environment, so as to bring scientific accordance for local governments to deal with climate change and disaster prevention and alleviation. The results indicate the annual number of extreme high temperature days ( EHTD) is on the significant rise by the rate of 0. 79 d/a, and the trend of inter-annual change of EHTD is accelerative by larger waving scale after the middle-late of 1980s, especially the rate of EHTD getting higher after the middle-late of 1990s. This is contrary to the extreme low temperature days (ELTD) , the annual number of ELTD is decreasing significantly by the rate of -0. 54 d/a and the trend of inter-annual change of ELTD is reducing by larger waving scale after the middle-latte of 1980s, and the rate of ELTD is lower after the middle-late of 1980s. The annual number of extreme precipitation days (EPD) is increasing significantly by the rate of 0.02 d/a, and the trend of inter-annual change of EPD is rising by larger and smaller waving scale before and after the middle of 1980s respectively, but the trend became contrary after the middle-late of 1990s, and the rate of EPD is higher after the middle of 1970s. The spatial distribution characteristics of inter-annual change trends and its significance of climate extremes have some differences, but the response to the global

  14. Mercury and Copper Accumulation During Last Fifty Years and Their Potential Ecological Risk Assessment in Sediment of Mangrove Wetland of Shenzhen,China%近50年来深圳湾红树林湿地Hg、Cu累积及其生态危害评价

    Institute of Scientific and Technical Information of China (English)

    李瑞利; 柴民伟; 邱国玉; 贺蓓

    2012-01-01

    pH.Contents of Hg and Cu in the whole depth of core ranged between 92-196 ng·g-1 and 29-83 μg·g-1,respectively.And both of them in sediment increased firstly and then decreased with the increasing soil depth.At 14 cm depth,contents of Hg and Cu reached up to the highest levels.Correspondingly,the ecological risk of Hg and Cu changed similarly with the contents of Hg and Cu.At 14 cm depth,the ecological risk indexes of Hg and Cu were at the highest levels of 39.10 and 13.85,respectively.The potential ecological risks of both Hg and Cu in sediments were mild.The rapid economical development of Hong Kong in 1960-1985 and Shenzhen in 1985-2000 contributed much to the Hg and Cu accumulation in mangrove wetland of Shenzhen Bay,China.Since the year of 2000,the reduction in contents of Hg and Cu has been expected as a consequence of the adoption of contamination control policies,improving the environment for growth of mangrove.In conclusion,the variations of core sediment heavy metal contents and its ecological risk assessment along the vertical profile reveal the interaction processes and extent of anthropogenic influences from the areas around the Shenzhen Bay and the catchments.

  15. Fifty Interesting Years: Higher Education Funding and Financial Management 1961-2011

    Science.gov (United States)

    Williams, Gareth

    2012-01-01

    During the half century of the AUA's existence UK universities have experienced the fastest rate of growth and most far-reaching changes in their history. Funding arrangements in particular have changed radically. Since 1961 the finance office has been transformed from a small group of bean counters into a key management group at the heart of all…

  16. Fifty-thousand-year vegetation and climate history of Noel Kempff Mercado National Park, Bolivian Amazon

    Science.gov (United States)

    Burbridge, Rachel E.; Mayle, Francis E.; Killeen, Timothy J.

    2004-03-01

    Pollen and charcoal records from two large, shallow lakes reveal that throughout most of the past 50,000 yr Noel Kempff Mercado National Park, in northeastern lowland Bolivia (southwestern Amazon Basin), was predominantly covered by savannas and seasonally dry semideciduous forests. Lowered atmospheric CO 2 concentrations, in combination with a longer dry season, caused expansion of dry forests and savannas during the last glacial period, especially at the last glacial maximum. These ecosystems persisted until the mid-Holocene, although they underwent significant species reassortment. Forest communities containing a mixture of evergreen and semideciduous species began to expand between 6000 and 3000 14C yr B.P. Humid evergreen rain forests expanded to cover most of the area within the past 2000 14C yr B.P., coincident with a reduction in fire frequencies. Comparisons between modern pollen spectra and vegetation reveal that the Moraceae-dominated rain forest pollen spectra likely have a regional source area at least 2-3 km beyond the lake shore, whereas the grass- and sedge-dominated savanna pollen spectra likely have a predominantly local source area. The Holocene vegetation changes are consistent with independent paleoprecipitation records from the Bolivian Altiplano and paleovegetation records from other parts of southwestern Amazonia. The progressive expansion in rain forests through the Holocene can be largely attributed to enhanced convective activity over Amazonia, due to greater seasonality of insolation in the Southern Hemisphere tropics driven by the precession cycle according to the Milankovitch Astronomical Theory.

  17. Fifty years after: some experiences of the medical care of prisoners of war.

    Science.gov (United States)

    Girdwood, R H

    1993-08-01

    Mention is made of Italian prisoners-of-war treated in Catterick military hospital but in October 1943 Italy joined the Allied side. An account is given of the medical condition of 78 Japanese POWs and of 228 members of the Japanese Indian Forces (JIFs) in a transit hospital in eastern India (now Bangladesh). Tropical sprue appeared to occur in an epidemic form each June and July in Burma and eastern India, but did not seem to have affected the Japanese or JIFs. A brief account is given of the condition of 180 European or Australian service men who had survived harsh conditions in Japanese POW camps until liberation in September 1945, then being admitted to a military hospital in Rangoon en route for home. Some had suffered from blindness as a result of malnutrition, the precise reason being uncertain, but there was some improvement after the injection of crude liver extract.

  18. Cryogenics for high-energy particle accelerators: highlights from the first fifty years

    Science.gov (United States)

    Lebrun, Ph

    2017-02-01

    Applied superconductivity has become a key technology for high-energy particle accelerators, allowing to reach higher beam energy while containing size, capital expenditure and operating costs. Large and powerful cryogenic systems are therefore ancillary to low-temperature superconducting accelerator devices – magnets and high-frequency cavities – distributed over multi-kilometre distances and operating generally close to the normal boiling point of helium, but also above 4.2 K in supercritical and down to below 2 K in superfluid. Additionally, low-temperature operation in accelerators may also be required by considerations of ultra-high vacuum, limited stored energy and beam stability. We discuss the rationale for cryogenics in high-energy particle accelerators, review its development over the past half-century and present its outlook in future large projects, with reference to the main engineering domains of cryostat design and heat loads, cooling schemes, efficient power refrigeration and cryogenic fluid management.

  19. Draft Budget of the Organization for the Fifty-First Financial Year 2005

    CERN Document Server

    2004-01-01

    A sa réunion du 15 septembre 2004 , le Comité des finances a recommandé au Conseil d'approuver le projet préliminaire de budget 2005 aux prix de 2004. La présente version tient compte des transferts du budget 2004 présentés dans le document "Budget 2004 - Transferts et dépassements de crédits" , du prélèvement dans la réserve pour imprévus pour le LHC indiqué dans le document "Réserve pour imprévus pour le LHC" et de divers ajustements mineurs. En conséquence, il est demandé au Comité des finances de recommander au Conseil d'approuver les modifications par rapport au projet préliminaire de budget 2005 présentées dans les tableaux de l'annexe 1.

  20. Fifty years of computer analysis in chest imaging: rule-based, machine learning, deep learning

    NARCIS (Netherlands)

    Ginneken, B. van

    2017-01-01

    Half a century ago, the term "computer-aided diagnosis" (CAD) was introduced in the scientific literature. Pulmonary imaging, with chest radiography and computed tomography, has always been one of the focus areas in this field. In this study, I describe how machine learning became the dominant techn

  1. One family's use of domestic fuels - a fifty year history

    Energy Technology Data Exchange (ETDEWEB)

    Tipler, W.

    1999-03-01

    The paper provides a detailed account of energy use (or rather energy purchased, since the records were of bills paid) in a family home since 1948 and discusses the lessons learned. From 1948-1958 the family lived in a 3-bed semi-detached house, from 1959-1967 in three 5-bed detached houses, from mid-1977 to late 1987 in a three-bedroomed terraced house on three floors and a three-bedroom detached house in Norfolk and from 1987 onwards lived in a detached house in London. (UK)

  2. Perspective: Fifty years of density-functional theory in chemical physics.

    Science.gov (United States)

    Becke, Axel D

    2014-05-14

    Since its formal inception in 1964-1965, Kohn-Sham density-functional theory (KS-DFT) has become the most popular electronic structure method in computational physics and chemistry. Its popularity stems from its beautifully simple conceptual framework and computational elegance. The rise of KS-DFT in chemical physics began in earnest in the mid 1980s, when crucial developments in its exchange-correlation term gave the theory predictive power competitive with well-developed wave-function methods. Today KS-DFT finds itself under increasing pressure to deliver higher and higher accuracy and to adapt to ever more challenging problems. If we are not mindful, however, these pressures may submerge the theory in the wave-function sea. KS-DFT might be lost. I am hopeful the Kohn-Sham philosophical, theoretical, and computational framework can be preserved. This Perspective outlines the history, basic concepts, and present status of KS-DFT in chemical physics, and offers suggestions for its future development.

  3. Essay: Fifty years of atomic, molecular and optical physics in Physical Review Letters.

    Science.gov (United States)

    Haroche, Serge

    2008-10-17

    The fiftieth anniversary of Physical Review Letters is a good opportunity to review the extraordinary progress of atomic, molecular, and optical physics reported in this journal during the past half-century. As both a witness and an actor of this story, I recall personal experiences and reflect about the past, present, and possible future of my field of research.

  4. Pediatric oncology at Hospital Infantil de Mexico: fifty-five years of accomplishment.

    Science.gov (United States)

    Medina-Sanson, A; Martínez-Avalos, A; Gallegos-Castorena, S; Juárez-Villegas, L E; González-Montalvo, P; Perales-Arroyo, A; Gallegos-González, E; Ayometzi-Ouchi, M T

    2002-09-01

    The Department of Oncology at Hospital Infantil de México Federico Gómez (HIMFG) was the first unit in our country, and one of the first in Latin America, to specialize in the management of children with cancer. The HIMFG is part of the National Institutes of Health of Mexico, and is a reference hospital with research, educative, and tertiary care medical function. To date, the HIMFG and the Instituto Nacional de Pediatria are the principal medical centers in which children with cancer receive comprehensive care.

  5. Fifty Years since the Coleman Report: Rethinking the Relationship between Schools and Inequality

    Science.gov (United States)

    Downey, Douglas B.; Condron, Dennis J.

    2016-01-01

    In the half century since the 1966 Coleman Report, scholars have yet to develop a consensus regarding the relationship between schools and inequality. The Coleman Report suggested that schools play little role in generating achievement gaps, but social scientists have identified many ways in which schools provide better learning environments to…

  6. Selection and Classification of United States Military Officers: A fifty-Year Bibliography (1937-1986)

    Science.gov (United States)

    1989-03-01

    Printing Office. 64 Michael , W.B. (1947). An investigation of the contribution of factors to tests and to their predictive value in two Army Air Forces...and criterion variables. Educational and Psychological Measurement, 9, 95-111. 83 Michael , W.o. (1949). Factor analyses of tests and criteria: A...Washington, DC: National Research Council, Committee on Selection and Training of Aircraft Pilots. 834 Taussig , J.K., Jr. (1942). A proposed method of

  7. Fifty years since the nuclear accident in Palomares (Almeria). Medical repercussions.

    Science.gov (United States)

    Laynez-Bretones, F; Lozano-Padilla, C

    2017-02-22

    In January 1966, 2 US military aircraft collided over the skies of Palomares (Almeria). One of them carried thermonuclear bombs, which released plutonium and other radioactive materials upon striking the ground. The most contaminated earth and plants were immediately removed. The Indalo Project was launched to study the effects of nuclear material on the inhabitants and environment of Palomares. A total of 1,077 inhabitants have been monitored since then, and the official version is that the ionising radiation has not been related to any type of disease. However, secrecy has surrounded much of the investigations, and no trustworthy epidemiological study has been conducted in the area. Approximately 500g of plutonium and americium remains in Palomares. Although the risk for the population appears to be low, this radioactive material should be removed as soon as possible.

  8. Islamic state or state Islam? Fifty years of state-Islam relations in Indonesia

    NARCIS (Netherlands)

    Bruinessen, M.M. van

    1996-01-01

    In what appeared like a dramatic reversal of previous policies towards organised Islam, President Soeharto in December 1990 gave his personal endorsement to the establishment of the Association of Indonesian Muslim Intellectuals (Ikatan Cendekiawan Muslim Se-Indonesia, ICMI), a body in

  9. Fifty Years of Yang-Mills Theory and my Contribution to it

    CERN Document Server

    Jackiw, Roman W

    2004-01-01

    On the fiftieth anniversary of Yang-Mills theory, I review the contribution to its understanding by my collaborators and me. Contents: 1.Gauge Theories and Quantum Anomalies; 2.Mathematical Connections; 3. Gauge Field Dynamics other than Yang-Mills; 4. Gauge Formalism for General Relativity Variables; A. Christoffel connection as a gauge potential, B. Gravitational Chern-Simons term from gauge theory Chern-Simons term, C. Coordinate transformations in general relativity and gauge theory, (i) Response to changes in coordinates (ii) Invariant fields and constants of motion. References.

  10. Review: Fifty Years Plus of Accelerometer History for Shock and Vibration (1940–1996

    Directory of Open Access Journals (Sweden)

    Patrick L. Walter

    1999-01-01

    Full Text Available This article summarizes the history of accelerometer development and the subsequent evolution of the commercial accelerometer industry. The focus is primarily on piezoelectric and piezoresistive accelerometers, although early resistance-bridge-type accelerometers are also described. The pioneer accelerometer manufacturing companies are identified and a chronology of technology development through today is presented.

  11. Fifty Years of Quasars From Early Observations and Ideas to Future Research

    CERN Document Server

    Marziani, Paola; Sulentic, Jack

    2012-01-01

    The 50th anniversary of the discovery of quasars in 1963 presents an interesting opportunity to ask questions about the current state of quasar research. Formatted as a series of interviews with noted researchers in the field, each of them asked to address a specific set of questions covering topics selected by the editors, this book deals with the historical development of quasar research and discusses how advances in instrumentation and computational capabilities have benefitted quasar astronomy and have changed our basic understanding of quasars. In the last part of the book the interviews address the current topic of the role of quasars in galaxy evolution. They summarise open issues in understanding active galactic nuclei and quasars and present an outlook regarding what future observational facilities both on the ground and in space might reveal. Its interview format, the fascinating topic of quasars and black holes, and the lively recollections and at times controversial views of the contributors make ...

  12. Islands as model systems in ecology and evolution: prospects fifty years after MacArthur-Wilson

    NARCIS (Netherlands)

    B.H. Warren; D Simberloff; R.E. Ricklefs; R. Aguilée; F.L. Condamine; D. Gravel; H. Morlon; N. Mouquet; J. Rosindell; J. Casquet; E. Conti; J. Cornuault; J.M. Fernández-Palacios; T. Hengl; S.J. Norder; K.F. Rijsdijk; I. Sanmartin; D. Strasberg; K.A. Trantis; L.M. Valente; R.J. Whittaker; R.G. Gillespie; B.C. Emerson; C. Thébaud

    2015-01-01

    The study of islands as model systems has played an important role in the development of evolutionary and ecological theory. The 50th anniversary of MacArthur and Wilson's (December 1963) article, ‘An equilibrium theory of insular zoogeography’, was a recent milestone for this theme. Since 1963, isl

  13. Fifty Years of Silent Service: A Peek Inside the CIA Library.

    Science.gov (United States)

    Newlen, Robert R.

    1998-01-01

    Describes the CIA (Central Intelligence Agency) library. Highlights include security measures, a day in the life of two CIA librarians, sample reference questions, collection development, the Historical Intelligence Collection, the CIA Web site, and library modernization. (JAK)

  14. Fifty years of tobacco carcinogenesis research: from mechanisms to early detection and prevention of lung cancer.

    Science.gov (United States)

    Hecht, Stephen S; Szabo, Eva

    2014-01-01

    The recognition of the link between cigarette smoking and lung cancer in the 1964 Surgeon General's Report initiated definitive and comprehensive research on the identification of carcinogens in tobacco products and the relevant mechanisms of carcinogenesis. The resultant comprehensive data clearly illustrate established pathways of cancer induction involving carcinogen exposure, metabolic activation, DNA adduct formation, and consequent mutation of critical genes along with the exacerbating influences of inflammation, cocarcinogenesis, and tumor promotion. This mechanistic understanding has provided a framework for the regulation of tobacco products and for the development of relevant tobacco carcinogen and toxicant biomarkers that can be applied in cancer prevention. Simultaneously, the recognition of the link between smoking and lung cancer paved the way for two additional critical approaches to cancer prevention that are discussed here: detection of lung cancer at an early, curable stage, and chemoprevention of lung cancer. Recent successes in more precisely identifying at-risk populations and in decreasing lung cancer mortality with helical computed tomography screening are notable, and progress in chemoprevention continues, although challenges with respect to bringing these approaches to the general population exist. Collectively, research performed since the 1964 Report demonstrates unequivocally that the majority of deaths from lung cancer are preventable.

  15. The development of soviet optics and spectroscopy during the past fifty years.

    Science.gov (United States)

    Frish, S

    1967-11-01

    A history of Soviet spectroscopy is given, with special emphasis on various areas indicating the earliest workers in each specialty and their principal successors; for example, the work of Rozhdestvenskii (anomalous dispersion); Fok (self-consistant field calculations), Terenin (photochemistry, atomic beams), Mandelstam (combination scattering), Vavilov (luminescence, quantum properties of light), Cerenkov (radiation), Chaika (atomic lifetimes), Gross (excitons), and Volkenstein (molecular vibrations).

  16. Fifty years of Water Resources Research: Legacy and perspectives for the science of hydrology

    National Research Council Canada - National Science Library

    Montanari, Alberto; Bahr, Jean; Blöschl, Günter; Cai, Ximing; Mackay, D. Scott; Michalak, Anna M; Rajaram, Harihar; Sander, Graham

    2015-01-01

    We present an overview of the contributions collected to celebrate the fiftieth anniversary of Water Resources Research along with a critical discussion of the legacy and perspectives for the science...

  17. Fifty years of Yang-Mills Theories: a phenomenological point of view

    CERN Document Server

    De Rújula, Alvaro

    2005-01-01

    On the occasion of the celebration of the first half-century of Yang--Mills theories, I am contributing a personal recollection of how the subject, in its early times, confronted physical reality, that is, its "phenomenology". There is nothing original in this work, except, perhaps, my own points of view. But I hope that the older practitioners of the field will find here grounds for nostalgia, or good reasons to disagree with me. Younger addicts may learn that history does not resemble at all what is reflected in current textbooks: it was orders of magnitude more fascinating.

  18. Fifty years of chasing lizards: new insights advance optimal escape theory.

    Science.gov (United States)

    Samia, Diogo S M; Blumstein, Daniel T; Stankowich, Theodore; Cooper, William E

    2016-05-01

    Systematic reviews and meta-analyses often examine data from diverse taxa to identify general patterns of effect sizes. Meta-analyses that focus on identifying generalisations in a single taxon are also valuable because species in a taxon are more likely to share similar unique constraints. We conducted a comprehensive phylogenetic meta-analysis of flight initiation distance in lizards. Flight initiation distance (FID) is a common metric used to quantify risk-taking and has previously been shown to reflect adaptive decision-making. The past decade has seen an explosion of studies focused on quantifying FID in lizards, and, because lizards occur in a wide range of habitats, are ecologically diverse, and are typically smaller and differ physiologically from the better studied mammals and birds, they are worthy of detailed examination. We found that variables that reflect the costs or benefits of flight (being engaged in social interactions, having food available) as well as certain predator effects (predator size and approach speed) had large effects on FID in the directions predicted by optimal escape theory. Variables that were associated with morphology (with the exception of crypsis) and physiology had relatively small effects, whereas habitat selection factors typically had moderate to large effect sizes. Lizards, like other taxa, are very sensitive to the costs of flight.

  19. Fifty Years Later: The Sequence, Structure and Function of Lacewing Cross-beta Silk

    Energy Technology Data Exchange (ETDEWEB)

    Weisman, Sarah; Okada, Shoko; Mudie, Stephen T.; Huson, Mickey G.; Trueman, Holly E.; Sriskantha, Alagacone; Haritos, Victoria S.; Sutherland, Tara D.; (CSIRO/MSE); (CSIRO)

    2009-12-01

    Classic studies of protein structure in the 1950s and 1960s demonstrated that green lacewing egg stalk silk possesses a rare native cross-beta sheet conformation. We have identified and sequenced the silk genes expressed by adult females of a green lacewing species. The two encoded silk proteins are 109 and 67 kDa in size and rich in serine, glycine and alanine. Over 70% of each protein sequence consists of highly repetitive regions with 16-residue periodicity. The repetitive sequences can be fitted to an elegant cross-beta sheet structural model with protein chains folded into regular 8-residue long beta strands. This model is supported by wide-angle X-ray scattering data and tensile testing from both our work and the original papers. We suggest that the silk proteins assemble into stacked beta sheet crystallites bound together by a network of cystine cross-links. This hierarchical structure gives the lacewing silk high lateral stiffness nearly threefold that of silkworm silk, enabling the egg stalks to effectively suspend eggs and protect them from predators.

  20. Islamic state or state Islam? Fifty years of state-Islam relations in Indonesia

    NARCIS (Netherlands)

    Bruinessen, M.M. van

    2007-01-01

    In what appeared like a dramatic reversal of previous policies towards organised Islam, President Soeharto in December 1990 gave his personal endorsement to the establishment of the Association of Indonesian Muslim Intellectuals (Ikatan Cendekiawan Muslim Se-Indonesia, ICMI), a body in which former

  1. Cryogenics for high-energy particle accelerators: highlights from the first fifty years

    CERN Document Server

    AUTHOR|(CDS)2067931

    2016-01-01

    Applied superconductivity has become a key technology for high-energy particle accelerators, allowing to reach higher beam energy while containing size, capital expenditure and operating costs. Large and powerful cryogenic systems are therefore ancillary to low-temperature superconducting accelerator devices – magnets and high-frequency cavities – distributed over multi-kilometre distances and operating generally close to the normal boiling point of helium, but also above 4.2 K in supercritical and down to below 2 K in superfluid. Additionally, low-temperature operation in accelerators may also be required by considerations of ultra-high vacuum, limited stored energy and beam stability. We discuss the rationale for cryogenics in high-energy particle accelerators, review its development over the past half-century and present its outlook in future large projects, with reference to the main engineering domains of cryostat design and heat loads, cooling schemes, efficient power refrigeration and cryogenic flu...

  2. Fifty years of plutonium exposure to the Mahattan Project plutonium workers: An update

    Energy Technology Data Exchange (ETDEWEB)

    Voelz, G.L.; Lawrence, J.N.P.; Johnson, E.R. [Los Alamos National Lab., TN (United States)

    1997-10-01

    Twenty-six white male workers who did the original plutonium research and development work at Los Alamos have been examined periodically over the past 50 y to identify possible health effects from internal plutonium depositions. Their effective doses range from 0.1 to 7.2 Sv with a median value of 1.25 Sv. As of the end of 1994, 7 individuals have died compared with an expected 16 deaths based on mortality rates of U.S. white males in the general population. The standardized mortality ratio (SMR) is 0.43. When compared with 876 unexposed Los Alamos workers of the same period, the plutonium worker`s mortality rate was also not elevated (SMR = 0.77). The 19 living persons have diseases and physical changes characteristic of a male population with a median age of 72 y (range = 69 to 86 y). Eight of the twenty-six workers have been diagnosed as having one or more cancers, which is within the expected range. The underlying cause of death in three of the seven deceased persons was from cancer, namely cancer of prostate, lung, and bone. Mortality from all cancers was not statistically elevated. The effective doses from plutonium to these individuals are compared with current radiation protection guidelines. 28 refs., 5 tabs.

  3. The jewel on the mountaintop the European Southern Observatory through fifty years

    CERN Document Server

    Madsen, Claus

    2013-01-01

    Authored by ESO senior advisor Claus Madsen, the present book comprises 576 action-packed pages of ESO history and dramatic stories about the people behind the organisation. This is the ultimate historical account about ESO and its telescopes in the southern hemisphere, but also about a truly remarkable European success story in research. Spanning the range from the first telescopes to the future platforms of the next generation, it shows how the improvement of the telescopes leads to a continuously changing view of the Universe. With 150 photos and illustrations. Produced especially for ESO's

  4. Draft Budget of the Organization for the Fifty-third Financial Year 2007

    CERN Document Server

    2006-01-01

    At its meeting of 18 October 20061, the Finance Committee recommended the Council to approve the 2007 Budget2 at 2006 prices. The present version has been up-dated to take into account the transfers from the 2006 Budget as per â? ?2006 Budget, Transfers and Expenditure in Excess of Provisionsâ??3 and various adjustments. The Finance Committee is invited to recommend Council to approve the 2007 Budget as shown in the document reviewed by this Committee in October and the additional up-dating of the present document.

  5. Fifty Years since the Coleman Report: Rethinking the Relationship between Schools and Inequality

    Science.gov (United States)

    Downey, Douglas B.; Condron, Dennis J.

    2016-01-01

    In the half century since the 1966 Coleman Report, scholars have yet to develop a consensus regarding the relationship between schools and inequality. The Coleman Report suggested that schools play little role in generating achievement gaps, but social scientists have identified many ways in which schools provide better learning environments to…

  6. Fifty years of CPGs: two neuroethological papers that shaped the course of neuroscience

    Directory of Open Access Journals (Sweden)

    Brian Mulloney

    2010-07-01

    Full Text Available Half a century ago, two independent papers that described unexpected results of experiments on locomotion in insects and crayfish appeared almost simultaneously. Together these papers demonstrated that an animal’s central nervous system (CNS was organized to produce behaviorally important motor output without the need for constant sensory feedback. These results contradicted the established line of thought that was based on interpretations of reflexes and ablation experiments, and established that in these animals the CNS contained neural circuits that could produce complex, periodic, multisegmental patterns of activity. These papers stimulated a flowering of research on central pattern-generating mechanisms that displaced reflex-based thinking everywhere except in medical physiology texts. Here we review these papers and their influence on thinking in the 1960s, 1970s, and today. We follow the development of ideas about central organization and control of expression of motor patterns, the roles of sensory input to central pattern-generating circuits, and integration of continuous sensory signals into a periodic motor system. We also review recent work on limb coordination that provides detailed cellular explanations of observations and speculations contained in those original papers.

  7. Fifty years of Moessbauer spectroscopy: from alloys and oxides to glasses and nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, C. E., E-mail: cjohnson@utsi.edu [University of Tennessee Space Institute, Center for Laser Applications (United States); Johnson, J. A. [University of Tennessee Space Institute, Department of Mechanical, Aerospace and Biomedical Engineering (United States)

    2012-03-15

    The Moessbauer Effect was discovered in 1957. In 1960 Moessbauer spectroscopy was born when two important papers appeared on (i) the magnetic hyperfine interaction and (ii) the electric monopole (isomer shift) and quadrupole interactions. These transformed an interesting phenomenon into a method for probing solids. Applications to magnetism, metals and alloys, chemical compounds, biological molecules, geology, archaeology and other sciences followed and are still of current interest. Two areas of research where Moessbauer spectroscopy is making unique contributions are in determining oxidation states in (i) glasses and (ii) nanoparticles. Some recent measurements are described.

  8. Fifty years of computer analysis in chest imaging: rule-based, machine learning, deep learning

    NARCIS (Netherlands)

    Ginneken, B. van

    2017-01-01

    Half a century ago, the term "computer-aided diagnosis" (CAD) was introduced in the scientific literature. Pulmonary imaging, with chest radiography and computed tomography, has always been one of the focus areas in this field. In this study, I describe how machine learning became the dominant

  9. Fifty million years of herbivory on coral reefs: fossils, fish and functional innovations

    Science.gov (United States)

    Bellwood, D. R.; Goatley, C. H. R.; Brandl, S. J.; Bellwood, O.

    2014-01-01

    The evolution of ecological processes on coral reefs was examined based on Eocene fossil fishes from Monte Bolca, Italy and extant species from the Great Barrier Reef, Australia. Using ecologically relevant morphological metrics, we investigated the evolution of herbivory in surgeonfishes (Acanthuridae) and rabbitfishes (Siganidae). Eocene and Recent surgeonfishes showed remarkable similarities, with grazers, browsers and even specialized, long-snouted forms having Eocene analogues. These long-snouted Eocene species were probably pair-forming, crevice-feeding forms like their Recent counterparts. Although Eocene surgeonfishes likely played a critical role as herbivores during the origins of modern coral reefs, they lacked the novel morphologies seen in modern Acanthurus and Siganus (including eyes positioned high above their low-set mouths). Today, these forms dominate coral reefs in both abundance and species richness and are associated with feeding on shallow, exposed algal turfs. The radiation of these new forms, and their expansion into new habitats in the Oligocene–Miocene, reflects the second phase in the development of fish herbivory on coral reefs that is closely associated with the exploitation of highly productive short algal turfs. PMID:24573852

  10. Fifty Interesting Years: Higher Education Funding and Financial Management 1961-2011

    Science.gov (United States)

    Williams, Gareth

    2012-01-01

    During the half century of the AUA's existence UK universities have experienced the fastest rate of growth and most far-reaching changes in their history. Funding arrangements in particular have changed radically. Since 1961 the finance office has been transformed from a small group of bean counters into a key management group at the heart of all…

  11. [Fifty years of public service for Quebec community psychiatry services. Part I].

    Science.gov (United States)

    Lesage, Alain

    2015-01-01

    This essay comprises 2 parts. It aims to recognize the public service of psychiatrists of the Département de psychiatrie de l'Université de Montréal who served at the provincial level of the Ministry of Health and Social Services for deinstitutionalisation of policies and organisation of services, at the service of people with severe mental disorders. First with Dr. Camille Laurin post-face of the 1962 book Les fous crient au secours! (Mentally ill patients cry for help); then the insight on the latest phase of differentiated specialised clinics by Dr. Denis Lazure, who participated in 1962 to the Bédard, Lazure, Roberts commission that launched community psychiatry, but who will also be Social Affairs Minister in the late '70 s; Dr. Arthur Amyot will sail through the budgetary issues when in the beginning of the '80s the mental health directorate was under Social Affairs; Dr. Luc Blanchet will be associated to a rich production of interdisciplinary reports by the advisory Mental Health Committee until its dismissal in 2003; and finally, Dr. André Delorme, who probably has the record of longevity at the head of the mental health directorate, transferred in 2003 under the deputy minister for medical and university affairs.The essay will propose since the beginning a grid or referential of four health services analysis. First; the arguments for community care by British and Italian psychiatrists and researchers, Thornicroft and Tansella. Second; system issues of mental health reforms proposed by Canadian psychiatric nurse and researcher Paula Goering. Third; the model of socio-political regulation of health system proposed by the Université de Montréal' health administration researcher Dr. André-Pierre Contandriopoulos; and Fourth; the structural tension between the medical and social sector signaled by the American medical sociologist, Leutz.The same phases of deinstitutionalization in other countries as UK, took place as followed: a) the asylum phase (before 1960); b) the psychiatry community (1960-2000); and c) the differentiated system (since 2000). The essay will evidence the long march towards hospitals without walls, interdisciplinary work, tension between cure and rehabilitation and a relative decreasing budget. This in conjunction with vulnerability in organisation and leadership, attributed to tension or burn out has revealed system deficits like the trans-institution towards homelessness or towards the judiciary system. The essay will conclude with a discussion on the opportunities and challenges of the very new Law 10 that reforms the general governance of the provincial and regional health and social services and hopes for a more balanced mental health care system in Quebec.

  12. Viewpoint – Fifty Years of Hydroelectric Development in Chile: A History of Unlearned Lessons

    Directory of Open Access Journals (Sweden)

    Michael Nelson

    2013-06-01

    Full Text Available The development of hydroelectricity in Chile illustrates a situation where water resources can be both well and badly managed when a private or public utility company, in this case ENDESA, is powerful enough to operate largely outside standard policy and bureaucratic processes. It successfully increased hydroelectric capacity more than fourfold over three decades characterised by periods of significant political instability. This was done without noticeable conflict due to its recognised efficiency and absence of environmental concerns in Chilean policy until the late 1980s. Since that time there has been increasing pressure from international agencies and NGOs to place more emphasis on environmental dimensions in development. The interplay among the diversity of agendas and tactics adopted by the interest groups attempting to influence decision on hydroelectric projects has, in some cases, been counterproductive. ENDESA chose to withhold information and modify EIA procedures as tactics to reduce costs. The NGOs’ single-minded dedication to preclusion of dam proposals tended to distort public debate. The government, presumably due to risk aversion, proved unwilling to take a proactive stance by not specifying and implementing requirements for approval of a dam project, providing a comprehensive policy framework for debate or facilitating dialogue on the issues.

  13. Fifty years of human space travel: implications for bone and calcium research.

    Science.gov (United States)

    Smith, S M; Abrams, S A; Davis-Street, J E; Heer, M; O'Brien, K O; Wastney, M E; Zwart, S R

    2014-01-01

    Calcium and bone metabolism remain key concerns for space travelers, and ground-based models of space flight have provided a vast literature to complement the smaller set of reports from flight studies. Increased bone resorption and largely unchanged bone formation result in the loss of calcium and bone mineral during space flight, which alters the endocrine regulation of calcium metabolism. Physical, pharmacologic, and nutritional means have been used to counteract these changes. In 2012, heavy resistance exercise plus good nutritional and vitamin D status were demonstrated to reduce loss of bone mineral density on long-duration International Space Station missions. Uncertainty continues to exist, however, as to whether the bone is as strong after flight as it was before flight and whether nutritional and exercise prescriptions can be optimized during space flight. Findings from these studies not only will help future space explorers but also will broaden our understanding of the regulation of bone and calcium homeostasis on Earth.

  14. Reflections on Over Fifty Years in Research and Development; Some Lessons Learned

    Science.gov (United States)

    2012-02-01

    man is an island, entire of itself…” John Donne, Meditation XVII A statement similar to Donne’s can be made about researchers and research...Feynman’s Lectures in Physics and the Berkeley Course in Physics. These were helpful, but I would have benefited more from classroom study. I

  15. [National Academy of Medicine, one hundred and fifty-four academic year].

    Science.gov (United States)

    Mansilla-Olivares, Armando

    2017-01-01

    El incalculable valor que atesora la Academia Nacional de Medicina, su enorme influencia y repercusión sobre la toma de decisiones médico-científico-epidemiológicas, radica única y exclusivamente en el dominio del conocimiento, la mente científica y el talento de todos y cada uno de sus miembros, desde su fundación en 1864 hasta nuestros días.

  16. The Armed Forces Epidemiological Board: Its First Fifty Years, 1940-1990

    Science.gov (United States)

    1990-02-01

    Alexander D. Langmuir, James M. Ruegsegger, and Elias Strauss. Pending the construction ot a Commission laboratory at Fort Bragg, the group spent...Sanders \\1 , Gulli’.er, F D. Forchhiimer, !- 1. , Alexander . R C IEpilenliL KuratoLonjuncti’. iti, CliiaI aand I’.perimental Stud% of anl Outbreak in...fluid of chick embryos infected with influenza virus B. Proc. Soc Exper Biol. & ,... 19,15, 59, 192-195. Meiklejohn , G , Eaton, M. D, and ,an Herick, W

  17. A mathematical medley fifty easy pieces on mathematics

    CERN Document Server

    Szpiro, George G

    2010-01-01

    Szpiro's book provides a delightful, well-written, eclectic selection of mathematical tidbits that makes excellent airplane reading for anyone with an interest in mathematics, regardless of their mathematical background. Excellent gift material. -Keith Devlin, Stanford University, author of The Unfinished Game and The Language of Mathematics It is great to have collected in one volume the many varied, insightful and often surprising mathematical stories that George Szpiro has written in his mathematical columns for the newspapers through the years. -Marcus du Sautoy, Oxford University, author

  18. Fifty Shades of Green: Pathway to Healthy Urban Living.

    Science.gov (United States)

    Nieuwenhuijsen, Mark J; Khreis, Haneen; Triguero-Mas, Margarita; Gascon, Mireia; Dadvand, Payam

    2017-01-01

    Currently half the world population lives in cities, and this proportion is expected to increase rapidly to 70% over the next years. Over the years, we have created large, mostly grey cities with many high-rise buildings and little green space. Disease rates tend to be higher in urban areas than in rural areas. More green space in cities could reduce these rates. Here, we describe the importance of green space for health, and make recommendations for further research. Green space has been associated with many beneficial health effects, including reduced all-cause and cardiovascular mortality and improved mental health, possibly through mediators, such as reduced air pollution, temperature and stress, and increased physical activity, social contacts, and restoration. Additional studies are needed to strengthen the evidence base and provide further guidelines to transport planners, urban planners, and landscape architects. We need more longitudinal studies and intervention studies, further understanding of the contribution of various mechanisms toward health, and more information on susceptible populations and on where, when, how much, and what type of green space is needed. Also needed are standardized methods for green space quality assessments and evaluations of effectiveness of green prescriptions in clinical practice. Many questions are ideally suited for environmental epidemiologists, who should work with other stakeholders to address the right questions and translate knowledge into action. In conclusion, a growing evidence base supports the hypothesis that greener cities are healthier cities.

  19. The Colima Economy from fifties to the eighties

    Directory of Open Access Journals (Sweden)

    José Luis Villa Aguijosa

    2008-03-01

    Full Text Available The economic development of Colima, from 50s to 80s decades, was characterized for three stages which are differentiated for some certain features given by the roll that plays the economic sectors from the behaviour of some basic indicators of economic activities like port, agricultural, tourism, mining and industry, an for the economic strategy proposed during these years.In the 50s and 60s years, the economic of Colima took two fundamental characteristics which transcendent to the 70s decade: the supremacy in the participation in the agricultural sector in the gross state product, specialy given with impulse of the industrialization agricultural, and the mining activation, transforming in the base of economic development to Colima. The second stage, is in the 70s decade, and is characterized by the dynamic that industrial stage takes above other sectors with more slowly growing tax, besides it is characterized for one reduction of the growth tax of the gross estate product.The characteristics of economic development of Colima during these years are: standstill of the agricultural activity, trade and services, growth of industry, the urbanization and new economic profile, and makes the bases from the new economic profile of the 80s, in the context of the trade opening. The economy of Colima presented a regional polarization of the activities, a deficient communications and transports, a tourist potential misuse, an important growing of the industrial activities, and the necessity to expand the potential of the Manzanillo port and their big expectatives in the Mexican pacific, and an important growing of an industrial sector highly polarized. This panorama impacted in the profile of the development of Colima in the next decade.The third moment which crosses the economic of Colima, and is presented in the decade of the 80s, is characterized by the beginning of an economic model based in the planning which ;designs; an integrated Colima to the

  20. Fifty most-cited articles in anterior cruciate ligament research.

    Science.gov (United States)

    Voleti, Pramod B; Tjoumakaris, Fotios P; Rotmil, Gayle; Freedman, Kevin B

    2015-04-01

    The number of times an article has been cited in the peer-reviewed literature is indicative of its impact on its respective medical specialty. No study has used citation analysis to determine the most influential studies pertaining to the anterior cruciate ligament (ACL). The primary aims of this study were to identify the classic works in ACL research using citation analysis and to characterize these articles to determine which types of studies have had the most influence on the field. A systematic query of ISI Web of Science (Thomson Reuters, Philadelphia, Pennsylvania) was performed for articles pertaining to the ACL, and the 50 most-cited articles were selected for evaluation. The following characteristics were determined for each article: number of citations, citation density, journal, publication year, country of origin, language, article type, article subtype, and level of evidence. The number of citations ranged from 219 to 1073 (mean, 326), and the citation densities ranged from 4.9 to 55.6 citations per year (mean, 18.2). All articles were published in 1 of 11 journals, with the most being published in The American Journal of Sports Medicine (46%) and The Journal of Bone and Joint Surgery American (30%). The most common decades of publication were the 1990s (34%), 1980s (28%), and 2000s (26%). The majority (68%) of articles originated from the United States, and all were written in English. By article type, 42% were basic science, and 58% were clinical. Of the clinical articles, 3% were Level I, 17% were Level II, 28% were Level III, and 52% were Level IV. The articles were heterogeneous with regard to article type, article subtype, and level of evidence and tended to have the following characteristics: high-impact journal of publication, recent publication year, US origin, English language, and low level of evidence. These works represent some of the most popular scientific contributions to ACL research. This list may aid residency and fellowship

  1. Sylvia Plath's The Bell Jar: a Mirror of American Fifties

    Directory of Open Access Journals (Sweden)

    Ghandeharion A.

    2015-12-01

    Full Text Available With its portrayal of a talented yet frustrated young American woman in the 1950s, Sylvia Plath's The Bell Jar (1963 depicts the experiences of a nineteen-year-old girl before her mental breakdown. Benefitting from a Friedanian second wave feminism, this paper aims to trace the root of disappointment and identity crisis in Plath's heroine, Esther Greenwood. It is understood that besides being a personal issue, her frustration is the outcome of sociocultural factors. The lack of role models and the contradictory messages sent by the media lead to her anxiety, disillusionment, and uncertainty. The Bell Jar proposes a solution: it is indeed possible for a woman to hold a fulfilling career and at the same time be a caring wife and a loving mother. And this is the answer Esther tries to figure out at a time when the boundaries between the domestic sphere and the outside world are clearly defined for women.

  2. Lateral root development in Arabidopsis: fifty shades of auxin.

    Science.gov (United States)

    Lavenus, Julien; Goh, Tatsuaki; Roberts, Ianto; Guyomarc'h, Soazig; Lucas, Mikaël; De Smet, Ive; Fukaki, Hidehiro; Beeckman, Tom; Bennett, Malcolm; Laplaze, Laurent

    2013-08-01

    The developmental plasticity of the root system represents a key adaptive trait enabling plants to cope with abiotic stresses such as drought and is therefore important in the current context of global changes. Root branching through lateral root formation is an important component of the adaptability of the root system to its environment. Our understanding of the mechanisms controlling lateral root development has progressed tremendously in recent years through research in the model plant Arabidopsis thaliana (Arabidopsis). These studies have revealed that the phytohormone auxin acts as a common integrator to many endogenous and environmental signals regulating lateral root formation. Here, we review what has been learnt about the myriad roles of auxin during lateral root formation in Arabidopsis.

  3. The fifty highest cited papers in anterior cruciate ligament injury.

    Science.gov (United States)

    Vielgut, Ines; Dauwe, Jan; Leithner, Andreas; Holzer, Lukas A

    2017-07-01

    The anterior cruciate ligament (ACL) is one of the most common injured knee ligaments and at the same time, one of the most frequent injuries seen in the sport orthopaedic practice. Due to the clinical relevance of ACL injuries, numerous papers focussing on this topic including biomechanical-, basic science-, clinical- or animal studies, were published. The purpose of this study was to determine the most frequently cited scientific articles which address this subject, establish a ranking of the 50 highest cited papers and analyse them according to their characteristics. The 50 highest cited articles related to Anterior Cruciate Ligament Injury were searched in Thomson ISI Web of Science® by the use of defined search terms. All types of scientific papers with reference to our topic were ranked according to the absolute number of citations and analyzed for the following characteristics: journal title, year of publication, number of citations, citation density, geographic origin, article type and level of evidence. The 50 highest cited articles had up to 1624 citations. The top ten papers on this topic were cited 600 times at least. Most papers were published in the American Journal of Sports Medicine. The publication years spanned from 1941 to 2007, with the 1990s and 2000s accounting for half of the articles (n = 25). Seven countries contributed to the top 50 list, with the USA having by far the most contribution (n = 40). The majority of articles could be attributed to the category "Clinical Science & Outcome". Most of them represent a high level of evidence. Scientific articles in the field of ACL injury are highly cited. The majority of these articles are clinical studies that have a high level of evidence. Although most of the articles were published between 1990 and 2007, the highest cited articles in absolute and relative numbers were published in the early 1980s. These articles contain well established scoring- or classification systems. The

  4. Competitiveness across the life span: the feisty fifties.

    Science.gov (United States)

    Mayr, Ulrich; Wozniak, Dave; Davidson, Casey; Kuhns, David; Harbaugh, William T

    2012-06-01

    Existing theories on life span changes in confidence or motivation suggest that individuals' preferences to enter competitive situations should gradually decline with age. We examined competitive preferences in a field experiment using real financial stakes in 25- to 75-year-olds (N = 543). The critical dependent variable was whether participants chose to perform a simple mental arithmetic task either under a piece-rate payment schedule (i.e., $.25 per solved item) or a competitive payment schedule ($.50 per solved item if the overall score is better than that of a randomly selected opponent, $0 otherwise). Results revealed that competitive preferences increased across the life span until they peaked around age 50, and dropped thereafter. We also found that throughout, men had a substantially larger preference for competing than women-extending previous findings on college-aged participants. The age/gender differences in preferences were neither accounted for by actual differences in performance nor individuals' subjective confidence. This first systematic attempt to characterize age differences in competitive behavior suggests that a simple decline conception of competitiveness needs to be reconsidered. PsycINFO Database Record (c) 2012 APA, all rights reserved

  5. "Double crap!" abuse and harmed identity in Fifty Shades of Grey.

    Science.gov (United States)

    Bonomi, Amy E; Altenburger, Lauren E; Walton, Nicole L

    2013-09-01

    While intimate partner violence (IPV) affects 25% of women and impairs health, current societal conditions-including the normalization of abuse in popular culture such as novels, film, and music-create the context to support such violence. Fifty Shades of Grey, a best-selling novel, depicts a "romantic" and "erotic" relationship involving 28-year-old megamillionaire, Christian Grey, and a 22-year-old college student, Anastasia Steele. We argue that the relationship is characterized by IPV, which is harmful to Anastasia. All authors engaged in iterative readings of the text, and wrote narrative summaries to elucidate themes. Validity checks included double review of the first eight chapters of the novel to establish consistency in our analysis approach, iterative discussions in-person and electronically to arbitrate discrepancies, and review of our analysis with other abuse and sexual practice experts. To characterize IPV, we used the U.S. Centers for Disease Control and Prevention's definitions of emotional abuse (intimidation/threats; isolation; stalking; and humiliation) and sexual violence (forced sex acts/contact against a person's will, including using alcohol/drugs or intimidation/pressure). To characterize harm, we used Smith's conceptualizations of perceived threat, managing, altered identity, yearning, entrapment, and disempowerment experienced by abused women. Emotional abuse is present in nearly every interaction, including: stalking (Christian deliberately follows Anastasia and appears in unusual places, uses a phone and computer to track Anastasia's whereabouts, and delivers expensive gifts); intimidation (Christian uses intimidating verbal and nonverbal behaviors, such as routinely commanding Anastasia to eat and threatening to punish her); and isolation (Christian limits Anastasia's social contact). Sexual violence is pervasive-including using alcohol to compromise Anastasia's consent, as well as intimidation (Christian initiates sexual encounters

  6. [Witchcraft medicine and folklore in Wushierbingfang ('Prescriptions for fifty-two diseases')].

    Science.gov (United States)

    Jia, Hai-yan

    2010-03-01

    One important characteristic of early stage of TCM is the intermixture of witches medicine and folklore. A few witch prescriptions in Wushierbingfang ('Prescriptions for fifty-two diseases') indicated the residual traces of the mixture of witch and medicine in the medical literatures. The witch prescriptions recorded in Wushierbingfang ('Prescriptions for fifty-two diseases') could be divided into supplication, Yu-step, exorcism, Nuo ritual and peach wood charms etc. Witchcraft developed into folklore and the application of witchcraft sometimes manifested as the form of folklore, which were also reflected in the records of ('Prescriptions for fifty-two diseases').

  7. Fiction or not? Fifty Shades is associated with health risks in adolescent and young adult females.

    Science.gov (United States)

    Bonomi, Amy E; Nemeth, Julianna M; Altenburger, Lauren E; Anderson, Melissa L; Snyder, Anastasia; Dotto, Irma

    2014-09-01

    No prior study has empirically characterized the association between health risks and reading popular fiction depicting violence against women. Fifty Shades--a blockbuster fiction series--depicts pervasive violence against women, perpetuating a broader social narrative that normalizes these types of risks and behaviors in women's lives. The present study characterized the association between health risks in women who read and did not read Fifty Shades; while our cross-sectional study design precluded causal determinations, an empirical representation of the health risks in women consuming the problematic messages in Fifty Shades is made. Females ages 18 to 24 (n=715), who were enrolled in a large Midwestern university, completed a cross-sectional online survey about their health behaviors and Fifty Shades' readership. The analysis included 655 females (219 who read at least the first Fifty Shades novel and 436 who did not read any part of Fifty Shades). Age- and race-adjusted multivariable models characterized Fifty Shades' readers and nonreaders on intimate partner violence victimization (experiencing physical, sexual and psychological abuse, including cyber-abuse, at some point during their lifetime); binge drinking (consuming five or more alcoholic beverages on six or more days in the last month); sexual practices (having five or more intercourse partners and/or one or more anal sex partner during their lifetime); and using diet aids or fasting for 24 or more hours at some point during their lifetime. One-third of subjects read Fifty Shades (18.6%, or 122/655, read all three novels, and 14.8%, or 97/655, read at least the first novel but not all three). In age- and race-adjusted models, compared with nonreaders, females who read at least the first novel (but not all three) were more likely than nonreaders to have had, during their lifetime, a partner who shouted, yelled, or swore at them (relative risk [RR]=1.25) and who delivered unwanted calls/text messages

  8. Fifty Shades a way readers put sex back in their lives

    DEFF Research Database (Denmark)

    Knudsen, Gry Høngsmark

    2014-01-01

    This is a guest blog from Gry Høngsmark Knudsen, a former student, who visited my “Women’s Economy” class this winter to report on her project about the reception of Fifty Shades of Grey. We all enjoyed her report, so I asked her to write a short blog for Double X Readers....

  9. The Elementary and Secondary Education Act at Fifty: A Changing Federal Role in American Education

    Science.gov (United States)

    Nelson, Adam R.

    2016-01-01

    For this first "History of Education Quarterly Policy Forum," we invited participants in the special Plenary Session at the 2015 Annual Meeting of the History of Education Society (HES) in St. Louis to publish their remarks on the historical significance of the Elementary and Secondary Education Act (ESEA) at fifty. Organized and…

  10. Understanding the Morphological Changes in the Polypropylene/Polyamide 6 Fifty/Fifty Blends by Interfacial Modifiers Based on Grafted Atactic Polypropylenes: Microscopic, Mechanical, and Thermal Characterization

    Directory of Open Access Journals (Sweden)

    E. P. Collar

    2015-01-01

    Full Text Available The main aim of the present work is to correlate the morphological changes observed in the modified PP/PA6 fifty/fifty blends molded at confined flow conditions with both their mechanical and thermal properties and the kind and the amount of the interfacial modifiers used. Both transmitted light optical microscopy in the positive phase contrast mode, PC TOM, and field emission scanning electronic microscopy, FE SEM, were the used techniques for, respectively, general morphology overview and fractures surface analysis. The interfacial modifiers, a succinic anhydride, aPP-SA, and a succinyl-fluorescein, aPP-SF/SA, grafted atactic polypropylenes obtained and well characterized in authors’ laboratories came from the chemical modification of an atactic polypropylene industrial by-product. The amounts of any of both the interfacial modifiers came coded by the Box-Wilson experiment design methodology applied to the overall PP/PA6 binary system, watching that the interfacial agent was not a third component on a ternary blend but a true interfacial modifier in a binary one. All the studies were carried out over suitable specimens according to each test procedure with no further material manipulations to preserve at any moment the morphology of the blends as they emerge from the compression molding step at confined flow conditions.

  11. Fifty Shades of Unsaid: Women’s Explicit and Implicit Attitudes Towards Sexual Morality

    OpenAIRE

    Tiziana Lanciano; Emanuela Soleti; Francesca Guglielmi; Ivan Mangiulli; Antonietta Curci

    2016-01-01

    The movie Fifty Shades of Grey has created a great deal of controversy which has reignited the debate on unusual and alternative sexual practices such as bondage. Erotophobic individuals have negative affect towards the type of sexual libertinism conveyed by the movie, while erotophilic persons have a positive attitude and emotional feelings towards this kind of sexual emancipation. Using the Implicit Association Test, this study aimed to explore the extent to which there is a difference in w...

  12. Extreme Markup: The Fifty US Hospitals With The Highest Charge-To-Cost Ratios.

    Science.gov (United States)

    Bai, Ge; Anderson, Gerard F

    2015-06-01

    Using Medicare cost reports, we examined the fifty US hospitals with the highest charge-to-cost ratios in 2012. These hospitals have markups (ratios of charges over Medicare-allowable costs) approximately ten times their Medicare-allowable costs compared to a national average of 3.4 and a mode of 2.4. Analysis of the fifty hospitals showed that forty-nine are for profit (98 percent), forty-six are owned by for-profit hospital systems (92 percent), and twenty (40 percent) operate in Florida. One for-profit hospital system owns half of these fifty hospitals. While most public and private health insurers do not use hospital charges to set their payment rates, uninsured patients are commonly asked to pay the full charges, and out-of-network patients and casualty and workers' compensation insurers are often expected to pay a large portion of the full charges. Because it is difficult for patients to compare prices, market forces fail to constrain hospital charges. Federal and state governments may want to consider limitations on the charge-to-cost ratio, some form of all-payer rate setting, or mandated price disclosure to regulate hospital markups. Project HOPE—The People-to-People Health Foundation, Inc.

  13. Year 2001 Tropical Cyclones of the World

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Year 2001 Tropical Cyclones of the World poster. During calendar year 2001, fifty tropical cyclones with sustained surface winds of at least 64 knots were observed...

  14. Fifty Cases of Parkinson's Disease Treated by Acupuncture Combined with Madopar

    Institute of Scientific and Technical Information of China (English)

    REN Xiao-ming

    2008-01-01

    objective;To search for an effective therapy for trealing motor disorder due to Parkinson's disease(PD).Methods;Fifty cases in a treatrnent group were treated by acupuncture combined with madopar,and 30 cases in a control group treated by madopar only.Results;A total effective rate of 92%was achieved with obvious alleviation of motor disorder in the treatment group,which was significantly higher than that in the control group(P<0.05).Conclusion;Acupuncture can enhance therapeutic effects of western medicine and lessen the dose of the medicine needed.

  15. Photography and modernization of the press in Brazilian capital: the first fifty years of the 20th Century

    Directory of Open Access Journals (Sweden)

    Silvana Louzada

    2009-12-01

    Full Text Available The process which created the conditions for the development of mass media press in Brazil was consolidated in the first half of the 20th Century with the emergence of newspaper companies based on an industrial form of production, the modernization of the writing style and design, plus the use of photography as a newsy element. There was a strong investment in technology in order to modernize the nation and photography, as a technical image par excellence, started to portray the acceleration of the passage of time that was accentuated by the 1890’s. In the beginning of the 20th century a new technological trend occurred mediated by the photographic apparatus and diffused through the newspaper and illustrated magazines pages that were multiplying in the nation’s capital, Rio de Janeiro. The press used photography and a series of technological artifacts to acquire the status of a modern entity and multiply the number of readers, changing its forms of production and its auto-referential discourse, starting to be more and more the icon of modernity. The technologies capable of giving a wider dimension to the concept of time and space were decisive in shaping the new symbolic world which emerged since the turn of the century. The world got closer and more visible, the perception of the “other” changed gradually and temporality took on a new dimension. This article traces a panorama of the use of photography by the main newspapers published in the capital of Brazil in the first half of the 20th century, seeking in photography the reflection of the modernizing process that Brazilian society desired and underwent.

  16. PHOTOGRAPHY AND MODERNIZATION OF THE PRESS IN BRAZILIAN CAPITAL: The First Fifty Years of the 20th Century

    Directory of Open Access Journals (Sweden)

    Silvana Louzada

    2009-12-01

    Full Text Available The process which created the conditions for the development ofmass media press in Brazil was consolidated in the first half of the 20th Century with the emergence of newspaper companies based on an industrial form of production, the modernization of the writing style and design, plus the use of photography as a newsy element. There was a strong investment in technology in order to modernize the nation and photography, as a technical image par excellence, started to portray the acceleration of the passage of time that was accentuated by the 1890’s. In the beginning of the 20th century a new technological trend occurred mediated by the photographic apparatus and diffused through the newspaper and illustrated magazines pages that were multiplying in the nation’s capital, Rio de Janeiro1. The press used photography and a series of technological artifacts to acquire the status of a modern entity and multiply the number of readers, changing its forms of production and its auto-referential discourse, starting to be more and more the icon of modernity. The technologies capable of giving a wider dimension to the concept of time and space were decisive in shaping the new symbolic world which emerged since the turn of the century. The world got closer and more visible, the perception of the “other” changed gradually and temporality took on a new dimension. This article traces a panorama of the use of photography by the main newspapers published in the capital of Brazil in the first half of the 20th century, seeking in photography the reflection of the modernizing process that Brazilian society desired and underwent.

  17. Report of NRL Progress. Fifty Years of Science for the Navy and the Nation, 1923-1973

    Science.gov (United States)

    1973-07-01

    available earlier, and more widely used. Window was the code name of the aluminum foil strips cut to be resonant in the Wuizburg frequency band...RESEARCH features that have been incorporated in later designs. It used all- aluminum construction and propellant tanks integral with the skin. The...propellant-type shaving creams and deodorants , something on the order of 30 pounds of fluorinated propellants of un- determined composition would

  18. Assessing Fifty Years of General Health Surveillance of Roe Deer in Switzerland: A Retrospective Analysis of Necropsy Reports

    Science.gov (United States)

    Pewsner, Mirjam; Origgi, Francesco Carlo; Frey, Joachim; Ryser-Degiorgis, Marie-Pierre

    2017-01-01

    General wildlife health surveillance is a valuable source of information on the causes of mortality, disease susceptibility and pathology of the investigated hosts and it is considered to be an essential component of early warning systems. However, the representativeness of data from such surveillance programs is known to be limited by numerous biases. The roe deer (Capreolus capreolus capreolus) is the most abundant ungulate and a major game species all over Europe. Yet, internationally available literature on roe deer pathology is scarce. The aims of this study were (1) to provide an overview of the causes of mortality or morbidity observed in roe deer in Switzerland and to assess potential changes in the disease pattern over time; and (2) to evaluate the value and limitations of a long term dataset originating from general wildlife health surveillance. We compiled 1571 necropsy reports of free ranging roe deer examined at the Centre for Fish and Wildlife Health in Switzerland from 1958 to 2014. Descriptive data analysis was performed considering animal metadata, submitter, pathologist in charge, laboratory methods, morphological diagnoses and etiologies. Recurrent causes of mortality and disease pictures included pneumonia, diarrhea, meningoencephalitis, actinomycosis, blunt trauma, predation, neoplasms and anomalies. By contrast, other diagnoses such as fatal parasitic gastritis, suspected alimentary intoxication and reproductive disorders appeared only in earlier time periods. Diseases potentially relevant for other animals or humans such as caseous lymphadenitis (or pseudotuberculosis), salmonellosis, paratuberculosis and listeriosis were sporadically observed. The disease pattern in roe deer from Switzerland was largely in accordance with previous reports. The observed fluctuations were consistent with methodical and/or personnel changes and varying disease awareness. Nevertheless, despite such limitations, the compiled data provide a valuable baseline. To facilitate comparison among studies, we recommend systematically archiving all case documents and fixed tissues and to perform data analyses more regularly and in a harmonized way. PMID:28103325

  19. From My Place: Teaching the Holocaust and Judaism at the University of Mississippi Fifty-Three Years after James Meredith

    Science.gov (United States)

    Johnson, Willa M.

    2016-01-01

    This essay explores classroom dynamics when students identify and connect their own painful experiences to structural racism or ethnocentrism exhibited in the Holocaust or parts of Jewish history. The intrusion of this proximal knowledge can be an obstacle to student learning. If engaged by professors, however, I argue that proximal knowledge can…

  20. Fifty-year spatiotemporal analysis of landscape changes in the Mont Saint-Hilaire UNESCO Biosphere Reserve (Quebec, Canada).

    Science.gov (United States)

    Béliveau, Marc; Germain, Daniel; Ianăş, Ana-Neli

    2017-05-01

    Diachronic analysis with a GIS-based classification of land-use changes based on aerial photographs, orthophotos, topographic maps, geotechnical reports, urban plans, and using landscape metrics has permitted insight into the driving forces responsible for landscape fragmentation in the Mont Saint-Hilaire (MSH) Biosphere Reserve over the period 1958-2015. Although the occurrence of exogenous factors, such as extreme weather and fires, can have a significant influence on the fragmentation of the territory in time and space, the accelerated development of the built environment (+470%) is nevertheless found to be primarily responsible for landscape fragmentation and the loss of areas formerly occupied by orchards, agriculture, and woodlands. The landscape metrics used corroborate these results, with a simplification of the shape of polygons, and once again reveal the difficulties of harmonizing different land uses. MSH has become somewhat of a forest island in a sea of residential development and agriculture. To counter this isolation of fragmented habitat components, forest corridors have been proposed and developed for the Biosphere Reserve and particularly for the core area. Two corridors, to the north and south, are used to connect the protected area and other wooded areas at the regional scale, in order to promote genetic exchange between populations of various species. In that regard, the forest buffer zone around the hill continues to play a key role and has great ecological value for species and ecological preservation and conservation. However, appropriate management and landscape preservation actions should recognize and focus on landscape composition and the associated geographical configuration.

  1. Reconstructing and analyzing China's fifty-nine year (1951–2009 drought history using hydrological model simulation

    Directory of Open Access Journals (Sweden)

    Z. Y. Wu

    2011-09-01

    Full Text Available The 1951–2009 drought history of China is reconstructed using daily soil moisture values generated by the Variable Infiltration Capacity (VIC land surface macroscale hydrology model. VIC is applied over a grid of 10 458 points with a spatial resolution of 30 km × 30 km, and is driven by observed daily maximum and minimum air temperature and precipitation from 624 long-term meteorological stations. The VIC soil moisture is used to calculate the Soil Moisture Anomaly Percentage Index (SMAPI, which can be used as a measure of the severity of agricultural drought on a global basis. We have developed a SMAPI-based drought identification procedure for practical uses in the identification of both grid point and regional drought events. As a result, a total of 325 regional drought events varying in time and strength are identified from China's nine drought study regions. These drought events can thus be assessed quantitatively at different spatial and temporal scales. The result shows that the severe drought events of 1978, 2000 and 2006 are well reconstructed, which indicates that the SMAPI is capable of identifying the onset of a drought event, its progression, as well as its termination. Spatial and temporal variations of droughts in China's nine drought study regions are studied. Our result shows that on average, up to 30% of the total area of China is prone to drought. Regionally, an upward trend in drought-affected areas has been detected in three regions (Inner Mongolia, Northeast and North from 1951–2009. However, the decadal variability of droughts has been weak in the rest of the five regions (South, Southwest, East, Northwest, and Tibet. Xinjiang has even been showing steadily wetter since the 1950s. Two regional dry centres are discovered in China as the result of a combined analysis on the occurrence of drought events from both grid points and drought study regions. The first centre is located in the area partially covered by the North and the Northwest, which extends to the southeastern portion of Inner Mongolia and the southwest part of Northeast. The second one is found on the central to southern portion of the South. Our study demonstrates the applicability and the value of using modeled soil moisture for reconstructing drought histories, and the SMAPI is useful for analyzing drought at different spatial and temporal scales.

  2. Fifty seven years of follow-up of the Israeli cohort of Laron Syndrome patients-From discovery to treatment.

    Science.gov (United States)

    Laron, Zvi; Kauli, Rivka

    2016-06-01

    Clinical and laboratory investigations of dwarfed children newly Jewish immigrants from Yemen and Middle East and who resembled patients with isolated growth hormone deficiency were started by our group in 1958. In 1963 when we found that they have high serum levels of hGH, we knew that we had discovered a new disease of primary GH insensitivity. It was subsequently coined Laron Syndrome (LS, OMIM #262500). The etiopathogenesis was disclosed by 2 liver biopsies demonstrating a defect in the GH receptor. Subsequent investigations demonstrated deletions or mutations in the GHR gene. The defect lead to an inability of IGF-I generation, resulting in severe dwarfism, obesity, and other morphologic and biochemical pathologies due to IGF-I deficiency. With the biosynthesis of IGF-I in 1986, therapeutic trials started. Following closely our cohort of 69 patients with LS enabled us to study its features in untreated and IGF-I treated patients. This syndrome proved to be a unique model to investigate the effects of IGF-I dissociated from GH stimulation. In recent studies we found that homozygous patients for the GHR mutations are protected lifelong from developing malignancies, opening new directions of research.

  3. Fifty Years of Soviet and Russian Drilling Activity in Polar and Non-Polar Ice: A Chronological History

    Science.gov (United States)

    2007-10-01

    86 Dzhantuganskoye Firn Plateau (Central Caucasus, drilling site #C5).....................................86 1984: Vavilov...32 Figure 13. Core auger used at Druznaya Station for drilling in firn . ..............................................34 Figure 14. Drilling...in October of 1956 just outside Mirny (Kapitsa 1958; Model 1959). Two holes to depths of 23.5 and 86.5 m were drilled using a conventional GP-1

  4. Fifty years of geophysical researches of glaciers in Institute of Geography, the Russian Academy of Sciences, 1966–2016

    Directory of Open Access Journals (Sweden)

    V. M. Kotlyakov

    2016-01-01

    Full Text Available In 1967‑2015, Institute of Geography of the USSR/Russian Academy of Sciences together with other organizations carried out field expeditions in different areas of mountain and polar glaciations in many regions: the Polar Urals, Caucasus, Pamir, Zailiysky and Jungar Alatau, Tien‑Shan, Pamir‑Alai, the Kamchatka Peninsula, the Pyrenees, the Arctic – Spitsbergen, Novaya Zemlya, Franz Josef and Severnaya Zemlya, and Antarctica – on the ice flow B, and in the sub‑Antarctic – Islands King George, Galindez, and Livingston. The gravimetric and ground and aerial radar observations were made in these expeditions. About 300 glaciers of different morphological types and sizes with cold, subpolar and temperate thermal regime were studied. Basic results of these studies are the following: (1 the new data on the ice thicknesses, ice volumes, subglacial relief, internal structure, and thermal state of the glaciers were obtained; (2 the two‑layered (polythermal glaciers consisting of the upper layer of cold ice and the lower layer of temperate water‑filled ice had been revealed in Svalbard for the first time; spatial distribution of cold, polythermal and temperate glaciers had been determined; (3 the evidences were obtained that measured changes in thickness of the upper cold ice layer in polythermal glaciers can be used to estimate the long‑period variations of regional climates and serve as regional paleothermometers; (4 methods for estimating the water content in temperate and polythermal glaciers from the RES data were developed; and its space‑time variations in temperate ices of the Svaldbald glaciers were estimated since even small water content inside of them can noticeably change their dynamic behavior; (5 methods for estimating the ice volume within glaciers in large regions of mountain and polar glaciations had been created; the ice storages were estimated in Svalbard, Franz Josef Land, Dzhungrsky Alatau, the Great Caucasus, and Mt. Elbrus; (6 detailed data on the ice thicknesses and the subglacial relief had been obtained for 40 glaciers in framework of different national and international programs and projects; the data can be used to solve a wide range of practical and theoretical problems, including numerical modeling. These studies demonstrated the following: (1 the use of monopulse radars VIRL‑6 and VIRL‑7 of decameter range (the central frequency is 20 MHz with digital recording of the radar and GPS data is quite efficient for ground‑based and airborne (from helicopters radio‑echo sounding of mountain and polar glaciers with their ice thicknesses up to 500–600 m; (2 it was found that thicknesses of glaciers in the Caucasus and Tien Shan can reach 330–430 m, while in regions of mountain, ice‑sheet and transitional glaciation on the Spitsbergen Archipelago – 300, 560 and 600 m, respectively, on the ice caps of the Franz‑Josef Land and Severnaya Zemlya – 450 and 813 m, and on King George and Livingston Islands (Sub‑Antarctica – 330 and 500 m; (3 large parts of ice caps and outlet glaciers in Svalbard, Franz Josef Land, Severnaya Zemlya which beds were located below the sea level were found. Precisely these parts can be undergone quick shortening due to climate warming, and, thus, cause formation of icebergs making threats for ships and gas‑oil marine platforms in the Barents and Kara seas; (4 data of the measurements made possible to calculate volumes of a number of investigated glaciers and ice caps and to estimate the ice storages in large areas of mountain and polar glaciations (the Jungar Alatau, Great Caucasus, Spitsbergen, Franz Josef Land; (5 decreasing of glacier volumes on the Franz Josef Land and some Spitsbergen glaciers for the last decades had been estimated. Analysis of the data obtained had shown that considerable part of polythermal glaciers in Spitsbergen belong to type of surging glaciers; they have the winter englacial runoff and form the near‑glacier icings. It allows considering such glaciers as dynamically unstable, predisposed to surges as well as possible sources of winter water supply and additional sources of paleoinformation about long‑period variations of regional climate.

  5. Philippe Aries's Discovery of Childhood after Fifty Years: The Impact of a Classic Study on Educational Research

    Science.gov (United States)

    Dekker, Jeroen J. H.; Groenendijk, Leendert F.

    2012-01-01

    This article looks at the impact of Philippe Aries's classic "L'Enfant et la vie familiale sous l'ancien regime", published in 1960. His well-known idea of the emergence of "Le sentiment de l'enfance" caused a lively debate among historians and social scientists resulting in fundamental contributions to our knowledge about the early phase of the…

  6. Fifty-year sedimentary record of heavy metal pollution in the lagoon of Oualidia (Moroccan Atlantic coast)

    Science.gov (United States)

    Zourarah, B.; Maanan, M.; Carruesco, C.; Aajjane, A.; Mehdi, K.; Conceição Freitas, M.

    2007-03-01

    The Oualidia lagoon is known for its heavy metal pollution resulting from mining and smelting activities since the late 19th century. Here, we report 137Cs and 210Pb activities and heavy metal concentration depth profiles from sediment cores retrieved in 1997. High mean sedimentation rates of 0.6-1 cm/y are indicated by 210Pb and 137Cs dating. The lagoon sediments have recorded heavy metal deposition and thus allow establishment of a connection between the temporal evolution of the heavy metal pollution and historical changes in smelting and waste-treatment proceedings. Through a study of the evolution of heavy metal contents, we can distinguish between two categories of metals: Al, Fe and Cr contents have varied around a mean value over the last seven decades and could have natural origins. Pb, Zn, Cu and Hg have relatively more elevated contents than those of the natural geochemical background, especially in the station in front of illegal sewerage discharges. These metals are enriched at depths between 20 and 30 cm; this corresponds to the period between 1960 and 1975, which was characterized by the setting up of the main suburbs and the first aquaculture farms that surround the lagoon. The pollution intensity of the lagoon is determined by enrichment factors and the geo-accumulation index, which show that the lagoon of Oualidia is unpolluted to moderately polluted on the Geo-I scale of Müler (1979. Schwermetalle in den Sedimenten, des Rheins-Veränderungen seit 1971. Umschau 79 (24), 778-783.).

  7. Secular Changes of Adiposity and Motor Development in Czech Preschool Children: Lifestyle Changes in Fifty-Five Year Retrospective Study

    National Research Council Canada - National Science Library

    Sedlak, Petr; Pařízková, Jana; Daniš, Robert; Dvořáková, Hana; Vignerová, Jana

    2015-01-01

    ..., for example, by Cattaneo et al. [11] and Parizkova et al. [12, 13], the increase of adiposity characterized by skinfold thickness was found already in preschool age, due also to decreasing age of adiposity rebound (AR) [14, 15]. All these changes concerning increasing adiposity have been accompanied by the worsening of motor dev...

  8. Õige valu õiges kohas. Lahinguväljal näeme! Noor veri vemmeldab : Slide-Fifty

    Index Scriptorium Estoniae

    2006-01-01

    9.-10. juunil Järvakandis toimuval festivalil Rabarock esinevatest ansamblitest: The Skreppers, Metsatöll, Slide Fifty (vt. www. rabarock. ee, www.skreppers.com, www.metsatoll.ee, www.slidefifty.com)

  9. Õige valu õiges kohas. Lahinguväljal näeme! Noor veri vemmeldab : Slide-Fifty

    Index Scriptorium Estoniae

    2006-01-01

    9.-10. juunil Järvakandis toimuval festivalil Rabarock esinevatest ansamblitest: The Skreppers, Metsatöll, Slide Fifty (vt. www. rabarock. ee, www.skreppers.com, www.metsatoll.ee, www.slidefifty.com)

  10. What makes a champion! over fifty extraordinary individuals share their insights

    CERN Document Server

    2014-01-01

    What drives great and successful individuals — be they athletes, artists, or scientists — or businesses, to achieve the extraordinary? Over fifty champions from all walks of life, brought together by Allan Snyder, draw on their experiences to explore the secrets of success in this inspiring, revealing and thought-provoking book. Hear from the authors what made a McDonalds' branch become the most successful in the world; how a cottage business is catapulted into a world brand; how a visual artist's works crosses almost every medium imaginable; how an Ernst and Young setup becomes a top-notch employer; or why many geniuses or brilliant individuals never become champions, while many 'ordinary' individuals do; why many people don't know about their talent; what constitutes a champion outcome; and the neurological explanation for championship. Straddling academia and practitioners in all fields — government, entertainment, sports, business, arts, education, medicine, media — the authors include business...

  11. Evaluating Efficiency of Tehran Stock Exchange: Case Study for Top Fifty Most Active Companies (TSE-50

    Directory of Open Access Journals (Sweden)

    Reza TALEBLOO

    2014-12-01

    Full Text Available Economics of information has been developing increasingly in economics literature in recent decades. Accordingly, the information plays a crucial role in efficiency of any market particularly capital market which deals more with this issue. As for the importance of information in stock exchange efficiency, the market efficiency is studied under three data sets in three forms including: 1- Information concerning the past prices, 2- All the released information and, 3- General Information and Confidential private information. Given these three types of information, market efficiency is checked in three weak, semi-strong and strong levels, respectively. This paper in order to examine the efficiency in the weak level employs a decomposed pattern with two stochastic and random terms for Top Fifty most active companies (TSE-50 in Tehran stock exchange based on both long and short horizons. The findings demonstrate that the indicator does not have efficiency in long horizon. This is while; the efficiency is verified in short horizon.

  12. Fifty Shades of Unsaid: Women's Explicit and Implicit Attitudes Towards Sexual Morality.

    Science.gov (United States)

    Lanciano, Tiziana; Soleti, Emanuela; Guglielmi, Francesca; Mangiulli, Ivan; Curci, Antonietta

    2016-11-01

    The movie Fifty Shades of Grey has created a great deal of controversy which has reignited the debate on unusual and alternative sexual practices such as bondage. Erotophobic individuals have negative affect towards the type of sexual libertinism conveyed by the movie, while erotophilic persons have a positive attitude and emotional feelings towards this kind of sexual emancipation. Using the Implicit Association Test, this study aimed to explore the extent to which there is a difference in women's attitudes towards sexual morality on an explicit and implicit level. Our findings found that erotophobic and erotophilic women differed only on an explicit level of sex guilt and moral evaluation, while no difference in the implicit measure was found.

  13. Fifty Shades of Unsaid: Women’s Explicit and Implicit Attitudes Towards Sexual Morality

    Directory of Open Access Journals (Sweden)

    Tiziana Lanciano

    2016-11-01

    Full Text Available The movie Fifty Shades of Grey has created a great deal of controversy which has reignited the debate on unusual and alternative sexual practices such as bondage. Erotophobic individuals have negative affect towards the type of sexual libertinism conveyed by the movie, while erotophilic persons have a positive attitude and emotional feelings towards this kind of sexual emancipation. Using the Implicit Association Test, this study aimed to explore the extent to which there is a difference in women's attitudes towards sexual morality on an explicit and implicit level. Our findings found that erotophobic and erotophilic women differed only on an explicit level of sex guilt and moral evaluation, while no difference in the implicit measure was found.

  14. Fifty Shades of Unsaid: Women’s Explicit and Implicit Attitudes Towards Sexual Morality

    Science.gov (United States)

    Lanciano, Tiziana; Soleti, Emanuela; Guglielmi, Francesca; Mangiulli, Ivan; Curci, Antonietta

    2016-01-01

    The movie Fifty Shades of Grey has created a great deal of controversy which has reignited the debate on unusual and alternative sexual practices such as bondage. Erotophobic individuals have negative affect towards the type of sexual libertinism conveyed by the movie, while erotophilic persons have a positive attitude and emotional feelings towards this kind of sexual emancipation. Using the Implicit Association Test, this study aimed to explore the extent to which there is a difference in women's attitudes towards sexual morality on an explicit and implicit level. Our findings found that erotophobic and erotophilic women differed only on an explicit level of sex guilt and moral evaluation, while no difference in the implicit measure was found. PMID:27872666

  15. Age-related changes in the macula. A histopathological study of fifty Indian donor eyes

    Directory of Open Access Journals (Sweden)

    Biswas Jyotirmay

    2002-01-01

    Full Text Available PURPOSE: Age-related macular degeneration (ARMD is clinically less common in India compared to the West. Therefore, clinicians are unfamiliar with histopathologic evidence of age-related macular changes in the Indian population. METHODS: Fifty consecutive human donor eyes removed for corneal grafting were studied for gross, microscopic and histochemical features of age-related changes in the macula in the Indian population. A horizontal block was cut from the globe including the optic disc, and the macula. Six sections, 6 microns thick, were cut from three levels in the macula at a distance of 140 microns. These were stained with haemotoxylin-eosin, periodic acid-Schiff, Mallory, Masson trichrome, alcian blue and von Kossa stains. The presence of basal laminar deposits, drusen and thickening and calcification of Bruch′s membrane in the macula were assessed at 400 x magnification using a modified version of Sark′s classification. RESULTS: Twenty-four donor eyes (48% had some form of age-related macular change. These included basal laminar deposits, hard drusen, soft drusen, extensive retinal pigment epithelium atrophy of the macula, and disciform degeneration of macula. A combination of changes was often seen. Age-related changes were more common in the seventh and eighth decade. CONCLUSION: Our study shows that histological changes characteristic of the early stages of age-related macular degeneration are fairly common in the Indian population. However, advanced macular changes are significantly rare.

  16. Community Energy Systems and the Law of Public Utilities. Volume Fifty. West Virginia

    Energy Technology Data Exchange (ETDEWEB)

    Feurer, D.A.; Weaver, C.L.

    1981-01-01

    A detailed description is presented of the laws and programs of the State of West Virginia governing the regulation of public energy utilities, the siting of energy generating and transmission facilities, the municipal franchising of public energy utilities, and the prescription of rates to be charged by utilities including attendant problems of cost allocations, rate base and operating expense determinations, and rate of return allowances. These laws and programs are analyzed to identify impediments which they may present to the implementation of Integrated Community Energy Systems (ICES). This report is one of fifty-one separate volumes which describe such regulatory programs at the Federal level and in each state as background to the report entitled Community Energy Systems and the Law of Public Utilities - Volume One: An Overview. This report also contains a summary of a strategy described in Volume One - An Overview for overcoming these impediments by working within the existing regulatory framework and by making changes in the regulatory programs to enhance the likelihood of ICES implementation.

  17. Community Energy Systems and the Law of Public Utilities. Volume Fifty-one. Wisconsin

    Energy Technology Data Exchange (ETDEWEB)

    Feurer, D.A.; Weaver, C.L.

    1981-01-01

    A detailed description is presented of the laws and programs of the State of Wisconsin governing the regulation of public energy utilities, the siting of energy generating and transmission facilities, the municipal franchising of public energy utilities, and the prescription of rates to be charged by utilities including attendant problems of cost allocations, rate base and operating expense determinations, and rate of return allowances. These laws and programs are analyzed to identify impediments which they may present to the implementation of Integrated Community Energy Systems (ICES). This report is one of fifty-one separate volumes which describe such regulatory programs at the Federal level and in each state as background to the report entitled Community Energy Systems and the Law of Public Utilities - Volume One: An Overview. This report also contains a summary of a strategy described in Volume One - An Overview for overcoming these impediments by working within the existing regulatory framework and by making changes in the regulatory programs to enhance the likelihood of ICES implementation.

  18. Quantitative analysis of digitopalmar dermatoglyphics in fifty male psoriatic spondylitis patients.

    Science.gov (United States)

    Cvjetičanin, Miljenko; Jajić, Zrinka

    2012-01-01

    By the quantitative dermatoglyphic analysis of digitopalmar ridge count in fifty male psoriatic spondylitis patients were researched 25 dermatoglyphics traits: number of epidermal ridges on the all ten fingers, their sum for five and ten fingers, four traits on the both palms, i.e. between a-b, b-c, c-d and a-d triradii, and atd angles and their bilateral sum in degrees. The data obtained were compared with those recorded in a control group of 200 pairs of imprints of phenotypically healthy males from the Zagreb area. Statistically significant differences to control were found in 13 variables in decreased ridge count in second, third, fourth and fifth finger on the right palm, and in their sum on the all five fingers, than in second, third, fourth and fifth finger on the left palm, and in their sum in the all fingers, and in the all ten fingers. Atd angle was decreased on the left palm, and on the both palm together. Accordingly a polygenetic system identical in some loci to polygenetic system predisposing to male psoriatic spondylitis susceptibility might be found responsible for dermatogliyphic pattern development.

  19. Fifty-eight cases of ocular ischemic diseases caused by carotid artery stenosis

    Institute of Scientific and Technical Information of China (English)

    LUO Rong-jiang; LIU Shao-rui; LI Xiao-min; ZHUO Ye-hong; TIAN Zhen

    2010-01-01

    Background The blood supply to the eye comes from the retinal central vascular system of the ophthalmic artery and the ciliary vascular system. The ophthalmic artery stems from the ipsilateral internal carotid artery. If occlusion or stenosis occurs in the carotid artery, the blood perfusion to the ophthalmic artery becomes insufficient, leading to signs and symptoms of anterior and posterior ocular ischemia. The objective of this study was to evaluate the clinical characteristics and risk factors of ocular ischemic diseases caused by carotid artery stenosis.Methods This study was a retrospective review of 145 patients with carotid artery stenosis. Fifty-eight patients who had symptoms of ocular ischemic disease caused by carotid artery stenosis formed group A and the other 87 patients who only had carotid artery stenosis formed group B. We analyzed the causes and course of disease, and relative risk factors,by comparing the two groups.Results The degree of carotid artery stenosis in group A was higher than that in group B. And group A had a greater decrease of ophthalmic artery flow. Male, hypertension, hyperlipidemia, and smoking were significantly related to carotid artery stenosis. Amaurosis fugax was the most common ocular symptom in group A. The ocular ischemic diseases mainly included ischemic optic neuropathy, central/branch retinal artery occlusion, ophthalmoplegia externa, and ocular ischemic syndrome.Conclusions Carotid artery stenosis correlates with ocular ischemic diseases. Ophthalmologists must observe for ocular symptoms, which were the onset symptoms in some patients.

  20. Community Energy Systems and the Law of Public Utilities. Volume Fifty-two. Wyoming

    Energy Technology Data Exchange (ETDEWEB)

    Feurer, D.A.; Weaver, C.L.

    1981-01-01

    A detailed description is presented of the laws and programs of the State of Wyoming governing the regulation of public energy utilities, the siting of energy generating and transmission facilities, the municipal franchising of public energy utilities, and the prescription of rates to be charged by utilities including attendant problems of cost allocations, rate base and operating expense determinations, and rate of return allowances. These laws and programs are analyzed to identify impediments which they may present to the implementation of Integrated Community Energy Systems (ICES). This report is one of fifty-one separate volumes which describe such regulatory programs at the Federal level and in each state as background to the report entitled Community Energy Systems and the Law of Public Utilities - Volume One: An Overview. This report also contains a summary of a strategy described in Volume One - An Overview for overcoming these impediments by working within the existing regulatory framework and by making changes in the regulatory programs to enhance the likelihood of ICES implementation.

  1. Fifty Shades: ambivalence about birth control in an erotic bestseller and its cultural implications.

    Science.gov (United States)

    Maierhofer, Waltraud; Israel, Emanuella

    2017-04-01

    The Fifty Shades trilogy by E.L. James has taken the world by storm and become a cultural phenomenon. The lack of contraceptive use in the erotic fiction, first pointed out by bloggers, is analysed in this article and compared to medical information. James may be praised for sexualising condom use. However, her protagonist makes poor choices in terms of hormonal contraception and is negligent about its use, resulting in an unintended pregnancy and resolved in marital bliss and motherhood. What is of more interest here than a possible message about contraceptive use, is the outcome that the fiction's negligence in birth control and responsibility affirms an ideology in which female sexuality and sexual experimentation can only be tolerated within the context of procreation and affirmation of motherhood. Subsequently, the cultural significance of the trilogy's popularity and its tension between sexual exploration, birth control and fertility is explored. In a globally popular fantasy published more than five decades after the introduction of the pill, the protagonist's lack of attention to reliable birth control leads to a telling dichotomy that combines adventurous exploration of female sexuality and affirmation of the nuclear family.

  2. 26 CFR 1.414(r)-4 - Qualified separate line of business-fifty-employee and notice requirements.

    Science.gov (United States)

    2010-04-01

    ...-employee and notice requirements. 1.414(r)-4 Section 1.414(r)-4 Internal Revenue INTERNAL REVENUE SERVICE... Bonus Plans, Etc. § 1.414(r)-4 Qualified separate line of business—fifty-employee and notice... business (as determined under § 1.414(r)-3) satisfies the 50-employee and notice requirements of §...

  3. Fifty Cases of Child Restless Syndrome Treated with the Integrated Method of Chinese Herbal Drugs and Auricular-Plaster Therapy

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Fifty cases of child restless syndrome were treated with oral administration of Chinese traditional herbal drugs plus auricular-plaster therapy from December 1998 to November 2001, and another 47 cases were treated with oral administration of methylphenidate as controls. The result is reported as follows.

  4. Fifty-Five Years of Pediatric Endocrinology and 50 Years of the Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases in Slovenia.

    Science.gov (United States)

    Battelino, Tadej

    2015-06-01

    Paediatric endocrinology started its independent development early in the general development of this specialty, with a strong focus on research and clinical excellence. Slovenian paediatric endocrinology was an integral part of the European paediatric endocrinology from its beginnings and a founding member of the first 'International Study Group for Diabetes in Children and Adolescents'. After the pioneering work of Prof. Lev Matajc, Prof. Ciril Kržišnik firmly integrated the Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases at the University Children's Hospital in Ljubljana in the international scientific community. In the last decade, the department participates in cutting-edge research and provides clinical services at highest international standards.

  5. The new algorithm for calculation of median lethal dose (LD50 and effective dose fifty (ED50 of Micrarus fulvius venom and anti-venom in mice

    Directory of Open Access Journals (Sweden)

    Saganuwan Alhaji Saganuwan

    2016-06-01

    Full Text Available One million people throughout the world are bitten yearly by poisonous snakes. Of this, one-tenth died and three-tenth suffer some forms of disabilities. In view of this, anti-snake venoms are currently being developed against viper and colubrid snake venoms using mice. Therefore, a new algorithm for calculation of median lethal dose (LD50 and effective dose fifty (ED50 was developed for Micrarus fulvius venom and antivenom respectively. This paper compared the formula of effective dose fifty (ED50 developed by Spearman and Karber with ideal median lethal dose (IMLD50 formula developed by Saganuwan with a view to bringing out their difference and similarity in calculation of ED50 that could be used to develop a new median lethal dose formula for calculation of Micrarus fulvius venom in mice. The findings revealed that ED50 value (477 mg/kg from Spearman and Karber’s formula (ED50=logED50=logX100-logFDn(Σt-n/2 is comparatively similar with ideal median lethal dose value (428.75 mg/kg from Saganuwan’s formula (MLD50 + MSD50/2. The new LD50 formula (LD50=ED503×Wm×10-4 yielded value (0.29 mg/kg of comparative significance with reported value (0.32 mg/kg. When ED50 is equal to 2LD50, the denominator of ED503 becomes 2. In conclusion, the new formula would yield low doses of snake anti-venoms with reduced possibility of hypersensitivity reaction.

  6. The Trainee Teacher and His Practice Class. Fifty Pointers for the Student-Teacher.

    Science.gov (United States)

    Rees, Alun L. W.

    1969-01-01

    This handbook, based on the author's experience of supervising the English practice-classes of trainee teachers, was originally compiled for the specific use of students at the National University of Trujillo, Peru, and consists of a list of pointers embracing the most prevalent of trainees' shortcomings observed over a period of years at all…

  7. Expanding the Education Universe: A Fifty-State Strategy for Course Choice

    Science.gov (United States)

    Brickman, Michael

    2014-01-01

    After twenty years of expanding school-choice options, state leaders, educators, and families have a new tool: course choice, a strategy for students to learn from unconventional providers that might range from top-tier universities or innovative community colleges to local employers, labs, or hospitals. In "Expanding the Education Universe:…

  8. Fifty-Six Cases of Acne Treated by Auricular Needle-Embedding

    Institute of Scientific and Technical Information of China (English)

    侯慧先; 吴童

    2002-01-01

    @@ Acne is an inflammatory disease often affecting the boys and girls at the pubescent age, with a tendency of affecting the females aged 30-45 years. We have treated 56 cases of acne by auricular needle-embedding with satisfactory therapeutic results as reported in the following.

  9. Harlequin, vampírur og mömmuklám. Um formúlu Twilight og Fifty Shades

    OpenAIRE

    Ragnheiður Jóhannsdóttir 1989

    2013-01-01

    Formúla Twilight seríunnar og Fifty Shades þríleiksins er tekin fyrir og skoðuð í samræmi við söguþráð Harlequin bækurnar, þar á eftir eru þær greindar út frá menningarlegu viðhorfi nútímans til fórnarlamba og gerenda, betur þekkt sem nauðgunarmenning.

  10. A comparison of one hundred and fifty consecutive parotidectomies for tumours and inflammatory disease.

    Science.gov (United States)

    Moody, A B; Avery, C M; Taylor, J; Langdon, J D

    1999-06-01

    The demographic profile and complications are compared and contrasted for 150 consecutive parotidectomies. All patients were under the care of one surgeon (JDL) over a twenty-year period (1977-1997). The case records and contemporaneous database were analysed retrospectively. 111 (74%) procedures were performed for tumours and 39 (26%) for inflammatory disease. The incidence of unexpected permanent facial nerve palsy was 1.8% in the tumour group and zero in the inflammatory group. The overall unexpected palsy rate was 1.3%. Transient paralysis was more common in the inflammatory group than the tumour group (61.5% compared with 33.3%, P<0.02) and was more likely to be panfacial (48.7% compared with 17.1%, P<0.0002). The overall incidence of Frey's syndrome was less than 20% and both salivary fistulae and sialocoeles were infrequent.

  11. Robot-assisted low anterior resection in fifty-three consecutive patients: an Indian experience.

    Science.gov (United States)

    Kenawadekar, R D; Dhange, R Z; Pandit, A; Bandawar, M S; Joshi, S; Agarwal, G; Jagtap, A P; Puntambekar, S

    2013-12-01

    From December 2005 to December 2009, we performed 150 laparoscopic colorectal procedures. Based on this experience, we started offering robot-assisted colorectal surgery from December 2009. This study is a prospective evaluation of consecutive patients in order to study the technical feasibility and oncological outcome of robot-assisted low anterior resection. This investigation was conducted at a single minimal access surgery institute. Between December 2009 and December 2011, 53 consecutive patients with rectal adenocarcinoma underwent a robot-assisted low anterior resection (LAR) or ultralow anterior resection (ULAR) with total mesorectal excision (TME), using the standard da Vinci 'S' model. Patient demographics, mean operative time, mean postoperative hospital stay, blood loss, days to first flatus, resumption of oral feeds, urinary incontinence, and sexual dysfunction were studied. Surgical and pathological outcomes such as quality of TME, free circumferential margins, and number of lymph nodes dissected were also evaluated. Robot docking and undocking times were noted. Of the 53 patients, 41 were men and 12 were women. Their mean age was 66.7 years (range 37-90 years). The ASA grades were distributed as follows: ASA I 15 (28.3 %), ASA II 25 (47.16 %), ASA III 12 (22.64 %), ASA IV 1 (1.88 %). The mean operative time was 180 min (150-230 min) and the mean blood loss was 101.6 ml (50-300 ml). The robot docking time was 10 min (15-25 min) and the undocking time was 5 min (3-10 min). The mean hospital stay was 8 days (7-15 days). None of the patients was converted to either laparoscopic or open procedure. The longitudinal and circumferential margins were negative in all patients. Histopathological reports of 45 patients showed complete TME while 8 patients showed nearly complete TME. No repositioning of the robot was needed for splenic flexure mobilization, thus decreasing the operative time. Along with TME, even the splenic flexure mobilization

  12. Fifty tours are being planned to mark CERN's 50th anniversary

    CERN Multimedia

    2004-01-01

    On 16 October 2004, CERN will open its doors to the public. The Visits Service is already busy with preparations for this day of special events to mark the fiftieth anniversary and is recruiting volunteers. A date for your diaries! On 16 October 2004, CERN will be holding an Open Day to mark its golden jubilee. The public will be invited to discover 50 years of history through tours of 50 different sites. Over thirty sites for the tours have already been identified, including the experiment halls, the assembly halls for the LHC detectors and magnets as well as the computer centre and the fire station. With a programme offering tours, talks, a play on a scientific theme and a variety of workshops, there will be something for everybody. A number of evening tours will be organised specifically for the inhabitants of Cessy, St Genis, Meyrin and Ferney Voltaire, where the experiment halls for CMS, ALICE, ATLAS and LHCb are respectively located. An area will even be set aside with stimulating games to enterta...

  13. Conference on Nuclear Energy and Science for the 21st Century: Atoms for Peace Plus Fifty - Washington, D.C., October 2003

    Energy Technology Data Exchange (ETDEWEB)

    Pfaltzgraff, Robert L [Institute for Foreign Policy Analysis

    2006-10-22

    This conference's focus was the peaceful uses of the atom and their implications for nuclear science, energy security, nuclear medicine and national security. The conference also provided the setting for the presentation of the prestigious Enrico Fermi Prize, a Presidential Award which recognizes the contributions of distinguished members of the scientific community for a lifetime of exceptional achievement in the science and technology of nuclear, atomic, molecular, and particle interactions and effects. An impressive group of distinguished speakers addressed various issues that included: the impact and legacy of the Eisenhower Administration’s “Atoms for Peace” concept, the current and future role of nuclear power as an energy source, the challenges of controlling and accounting for existing fissile material, and the horizons of discovery for particle or high-energy physics. The basic goal of the conference was to examine what has been accomplished over the past fifty years as well as to peer into the future to gain insights into what may occur in the fields of nuclear energy, nuclear science, nuclear medicine, and the control of nuclear materials.

  14. Fifty shades of inhibition.

    Science.gov (United States)

    Maffei, Arianna

    2016-12-22

    Inhibitory circuits are essential for brain function. Our understanding of their synaptic organization has advanced extensively with the identification and classification of an impressive variety of neuron groups, receptor types, and patterns of connectivity. However, the conceptual discussion regarding the role of in neural circuits still revolves around the idea that its primary role is to regulate circuit excitability. Here, I will focus on recent findings from cortical circuits and argue that inhibitory circuits are central to the integration of incoming inputs and can promote sophisticated fine-scale control of local circuits. I propose that inhibitory circuits should not be viewed so much as brakes on principal neurons activity, but as primary contributors to a variety of neural network functions.

  15. Fifty shades of black

    Science.gov (United States)

    Cartwright, Jon

    2015-11-01

    Creating dark materials that prevent reflections has become hot competition recently, with Guinness World Records having to keep revising the darkest substance yet created. But depending on who's asking, the best black may not be the blackest black, as Jon Cartwright discovers.

  16. General relativity 50 years old

    CERN Multimedia

    1966-01-01

    In May 1916, 'The Foundations of General Relativity Theory' by Albert Einstein was published in 'Annalen der Physik'. Fifty years later, this major contribution to scientific thought still has a rather isolated position with respect to the main-stream of scientific theory. (In contrast, the Special Theory of Relativity is one of the cornerstones of sub-nuclear physics.) To mark the anniversary of the publication of Einstein's paper a theoretician from CERN discusses the theory and its present status.

  17. Cincuenta años después (Fifty years later - DOI: 10.5752/P.2175-5841.2011v9n24p1246

    Directory of Open Access Journals (Sweden)

    Julio de Santa Ana

    2012-01-01

    Full Text Available ResumenEl artículo sitúa su reflexión en el tema del ecumenismo, relacionándolo con las propuestas de aggiornamento expresadas por el Vaticano II. Hace también alusión al ámbito de las mudanzas en el seno del protestantismo, de las Iglesias ortodoxas e incluso del cristianismo romano. Además alude a los grandes nombres que trazaron la reflexión teológica en el período de crisis que antecedió al evento –hablamos de aspectos que acabaron incidiendo en los debates conciliares. Siguiendo a Gutiérrez, el artículo destaca tres dimensiones relativas a la búsqueda del diálogo de la Iglesia con el mundo contemporáneo: la urgencia de ser actual, la perspectiva ecuménica y la solidaridad con los pobres. Analiza los “caminos equivocados” que fueron adoptados por la Iglesia en lo concerniente a las propuestas ecumênicas del Concilio: el tomar un “execesivo cuidado” en lo que respecta al mundo moderno, las posiciones de intolerância frente a lo diferente, la comprensión reduccionista del ecumenismo. Hace mención a la exigência de construir relaciones que tengan como bases: la gracia  y el amor. Por último, propone la tesis de que “no puede existir un sentido del diálogo, un encuentro entre los seres diferentes, sin la libertad”.Palabras-clave: Iglesia. Vaticano II. Ecumenismo. Diálogo inter-religioso. AbstractThis article focuses its discussion on the theme of ecumenism, in relation to the catholic proposal of aggiornamento expressed by Vatican II. The text refers to the changes within the Protestantism, the Orthodox churches and also within the Roman Christianity. It also mentions the relevant names that marked theological reflection in those times of crisis prior to the Council. Following the author´s thought, the text highlights three dimensions of the dialogue of the Church with the contemporary world: the urgency in getting things update, the ecumenical perspective and the solidarity with the poor. The article evaluates the "wrong path" taken by the Church in relation to the propositions of the ecumenical council: attitudes of intolerance to the different and the reductionist understanding of ecumenism. It also refers to the need to build relationships whose bases are the grace and love. The article finally expresses the following thesis: "there cannot be a sense of dialogue among different beings without freedom."Keywords: Church. Vatican II. Ecumenism. Inter-religious Dialogue.- DOI: 10.5752/P.2175-5841.2011v9n24p1246

  18. Cetáceos del Pacífico de Guatemala: Cincuenta años de historia Guatemala's Pacific Cetaceans: Fifty Years of History

    Directory of Open Access Journals (Sweden)

    Andrea A. Cabrera Arreola

    2014-10-01

    Full Text Available En Guatemala el estudio de los cetáceos inició en la década de los sesenta con los primeros registros de varamiento y captura incidental. Sin embargo, pocos trabajos científicos con datos de cetáceos han sido publicados. Con el objetivo de centralizar la información de cetáceos y obtener conocimiento biológico para el desarrollo de planes de manejo y conservación, se realizó una revisión bibliográfica de cetáceos en Guatemala que recaba información de los últimos 50 años. Se obtuvo un total de 1,014 registros de avistamiento (1979-2011, 62 registros de captura incidental (1961/85 y 16 registros de varamientos (1975, 2007-2012, los cuales se analizaron en mapas batimétricos y en mapas de presiones antropogénicas. Se identificaron diecinueve especies pertenecientes a cinco familias de cetáceos, incluyendo Balaenopteridae, Delphinidae, Ziphiidae, Kogiidae y Physeteridae. El esfuerzo y área de muestreo varió durante 1961-2012. Se identificaron diferentes patrones de distribución especie-específicos. La mayoría de avistamientos se registraron cerca de zonas con topografía compleja. Aunque los eventos de captura incidental se registraron únicamente en alta mar, los resultados sugieren que especies de distribución costera se encuentran en zonas con mayor riesgo antropogénico. Se reportaron ocho especies de cetáceos varados, eventos ocurridos principalmente en el departamento de Escuintla desde el año 2007. Debido a la gran diversidad en los patrones de distribución, comportamiento y uso de hábitat de los cetáceos, combinado con los riesgos antropogénicos de la zona, es necesario que se considere un enfoque integral cuando se implementen planes de manejo y conservación marina en Guatemala.

  19. Fifty years after Martin Luther King’s speech, Obama’s gradual approach to political change still needs King’s visionary dream to play against

    OpenAIRE

    Kier, Ruth

    2013-01-01

    Last week saw the 50th anniversary of Martin Luther King’s ‘I have a dream’ speech, which was marked at an\\ud event by President Barack Obama. Rune Kier writes that while King’s speech was one which\\ud articulated abrupt and revolutionary change to achieve equality against an apparently stagnant establishment,\\ud Obama’s rhetoric is that of gradual, hard won, political change. Despite these differences, King’s speech is still\\ud the vision that Obama is striving for.

  20. Extended radical mastectomy versus simple mastectomy followed by radiotherapy in primary breast cancer. A fifty-year follow-up to the Copenhagen Breast Cancer randomised study

    DEFF Research Database (Denmark)

    Johansen, H.; Kaae, S.; Jensen, Maiken Brit;

    2008-01-01

    From November 1951 to December 1957, 666 consecutive patients with untreated primary breast cancer admitted to the Radium Center in Copenhagen were randomised before their operability was evaluated into two groups, simple mastectomy with postoperative radiotherapy or extended radical mastectomy...

  1. Brian R. Billman and Gary M. Feinman, editors, Settlement Pattern Studies in the Americas: Fifty Years Since Viru, Smithsonian Institution Press. Washington D.C.

    OpenAIRE

    David L. Browman

    2000-01-01

    The most significant historical information in this volume is the short (3 pages) piece by Gordon R. Wllley entitled "The Viru Valley Project and Settlement Archaeology: Some Reminiscences and Con­temporary Comments." These remarks add to Willey's original background notes in his seminal 1953 publication, as well as his own retrospective look at the program in a chapter in his 1974 volume. Wllley notes that when he started out in 194...

  2. Brian R. Billman and Gary M. Feinman, editors, Settlement Pattern Studies in the Americas: Fifty Years Since Viru, Smithsonian Institution Press. Washington D.C.

    Directory of Open Access Journals (Sweden)

    David L. Browman

    2000-11-01

    Full Text Available The most significant historical information in this volume is the short (3 pages piece by Gordon R. Wllley entitled "The Viru Valley Project and Settlement Archaeology: Some Reminiscences and Con­temporary Comments." These remarks add to Willey's original background notes in his seminal 1953 publication, as well as his own retrospective look at the program in a chapter in his 1974 volume. Wllley notes that when he started out in 1946, at age 33, on the Viru venture, he was not at all sure what he was going to do. The original project was not one primarily devoted to settlement pattern study, rather it developed as the outcome of a suggestion by Wendell C. Bennett that post-war research on Peruvian archaeology could be moved forward by having several archaeologists from several institutions focus their efforts upon a single Peruvian coastal valley. The Viru valley was ultimately settled upon, because not only had Bennett had worked there earlier and knew something of its cultural sequence, but the valley was of a modest size and thus, with the resources available, a viable project.

  3. Fifty Years in the Development of a Glutaminergic-Dopaminergic Optimization Complex (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome: A Pictorial

    Science.gov (United States)

    Blum, K; Febo, M; Badgaiyan, RD

    2016-01-01

    Dopamine along with other chemical messengers like serotonin, cannabinoids, endorphins and glutamine, play significant roles in brain reward processing. There is a devastating opiate/opioid epidemicin the United States. According to the Centers for Disease Control and Prevention (CDC), at least 127 people, young and old, are dying every day due to narcotic overdose and alarmingly heroin overdose is on the rise. The Food and Drug Administration (FDA) has approved some Medication-Assisted Treatments (MATs) for alcoholism, opiate and nicotine dependence, but nothing for psychostimulant and cannabis abuse. While these pharmaceuticals are essential for the short-term induction of “psychological extinction,” in the long-term caution is necessary because their use favors blocking dopaminergic function indispensable for achieving normal satisfaction in life. The two institutions devoted to alcoholism and drug dependence (NIAAA & NIDA) realize that MATs are not optimal and continue to seek better treatment options. We review, herein, the history of the development of a glutaminergic-dopaminergic optimization complex called KB220 to provide for the possible eventual balancing of the brain reward system and the induction of “dopamine homeostasis.” This complex may provide substantial clinical benefit to the victims of Reward Deficiency Syndrome (RDS) and assist in recovery from iatrogenically induced addiction to unwanted opiates/opioids and other addictive behaviors. PMID:27840857

  4. A fifty-year journey of China towards the world economy : an empirical study on the determinants of China´s bilateral trade relations

    NARCIS (Netherlands)

    Zhang, Jianhong

    2005-01-01

    Tot 1978 was de communistische volksrepubliek China een geïsoleerd land. De buitenlandse handel was een staatsmonopolie; de omvang was beperkt en het betrof voornamelijk transacties met naaste buren. Nu is China een van de belangrijkste handelsnaties in de wereld. Het aantal handelspartners – ook ov

  5. Recollections of a Dental Researcher. Fifty Years at the U.S. National Bureau of Standards: Interviews with George C. Paffenbarger, DDS,

    Science.gov (United States)

    1980-10-01

    were!) We designed partial and complete dentures , constructed a vulcanite, with wire clasps and bars for the partial dentures . I had an advantage over...idenfify by block nutriber) Dentist George C. Paffenbarger’s autobiography Dentistry’s progress in the History of dentistry military Military dentistry... history Paffenbarger’s contributions in ;National Bureau of Standards’ dentistry dentistrY Dental materials research Navy en i t Rear Admiral....... b

  6. 激光发明50周年的几点启示%Some enlightenment from fifty years of laser development

    Institute of Scientific and Technical Information of China (English)

    杜祥琬

    2010-01-01

    2010年是激光发明50周年.文章首先同顾了50年前激光的发明,说明基础科学创新的重大引领作用.接着概述了50年米激光领域的重大进展,包括激光器技术及其应用研究的进展;举例说明了激光应用对基础科学的反馈和推动作用;归纳了高能激光器的几个发展趋势;分析了激光的军事应用及其科学技术支撑.最后给出了激光50年发展史的4点启示和今后的3类发展方向.

  7. Cincuenta años de política fiscal en materia de vivienda = Fifty years of tax policy in housing

    Directory of Open Access Journals (Sweden)

    Carlos Carbajo Nogal

    2012-03-01

    Full Text Available ResumenEl objetivo de este trabajo es analizar la evolución de la política de vivienda en nuestro país a partir de los años sesenta y hasta la actualidad, estudiando para ello los planes plurianuales de subsidios y ayudas a la vivienda. Estos actúan como instrumentos presupuestarios que incluyen medidas de fomento basadas, en la mayor parte de los casos en ayudas a fondo perdido, en la financiación de los diferenciales de interés o de la propia cuota o en la concesión de créditos preferenciales en función de los ingresos de las familias y del tipo de viviendas protegidas en cada periodo; se hace particular hincapié en los beneficios de naturaleza fiscal, que en los años sesenta y setenta se centran en la ampliación del hasta entonces escaso parque de viviendas sobre las que la población española empezaba ya a decantarse sobre el régimen de tenencia en propiedad. Desde esa fecha hasta hoy las políticas públicas han ido evolucionando y pese al alto nivel de viviendas en régimen de propiedad, los poderes públicos han vuelto de nuevo la vista al mercado del alquiler como posible respuesta al problema de la vivienda.AbstractThe aim of this paper is to analyze the evolution of housing policy in our country since the sixties and until today, by assessing grant term plans and housing assistance. These act as budgetary instruments including building measures based, in most cases in refundable aid in the financing of interest rate differentials or own quota or preferential lending based on income family and the type of housing in each period; places particular emphasis on the benefits of a fiscal nature, that at first, in the sixties and seventies are focused on expanding the hither to scarce housing stock on that the Spanish population was beginning to opt for tenure in property. From then until now public policies have evolved and despite the high level of housing ownership, public authorities have become again the view to the rental market as a possible answer to the housing problem.

  8. Wie Effektiv ist Microteaching? Ein Uberblick uber funfundreifsig Jahre Forschung (How Effective Is Micro-Teaching? A Survey of Fifty-Three Years of Research).

    Science.gov (United States)

    Klinzing, Hans Gerhard

    2002-01-01

    Reviews 200+ studies on microteaching. Argues that the use of microteaching in pre- and inservice education leads to positive and long-term effects in the acquisition of verbal and non-verbal behaviorial patterns, integration of learning into individual behavioral repertoire, and in the transfer into professional teaching practice. (CAJ)

  9. [52th Commemoration of French Journal of Plastic Aesthetic Surgery (1956-2007). Fifty-four years of editorial; five Editors-in-chief].

    Science.gov (United States)

    Cariou, J-L

    2007-08-01

    The french Society of Plastic Reconstructive and Aesthetic Surgery (SOF.CPRE) is born December 3th 1952. Initially without "aesthetic", this "key-word" is agreed in 1983 and the symbols are advanced since: SFCPR, SFCPRE, SOF.CPRE. Its official organ, formerly included in Annales de chirurgie (1954-1955), become Annales de chirurgie plastique in 1956, Annales de chirurgie plastique et esthétique in 1983 and finally Annales de chirurgie plastique esthétique (ACPE) in 1992. Since the origin, five Editors-in-chief succeded: Claude Dufourmentel, Raymond Vilain, Jean-Pierre Lalardrie, Claude Lê-Quang, Jean-Luc Cariou. Four of them are alive, Raymond Vilain is dead. The author relate here the natural story of these five editors who had all a triple route: personnal, surgical and editorial.

  10. Fifty Years of College Choice: Social, Political and Institutional Influences on the Decision-Making Process. New Agenda Series. Volume 5, Number 3

    Science.gov (United States)

    Kinzie, Jillian; Palmer, Megan; Hayek, John; Hossler, Don; Jacob, Stacy A.; Cummings, Heather

    2004-01-01

    The college-choice process is complex and affects many high school students, family members and public policy-makers, as well as institutions of higher education. This report provides an overview of the college-choice process for traditional-age students and examines how it has evolved during the last half of the 20th century. Material from the…

  11. Perspectives on the 2014 ESC/EACTS Guidelines on Myocardial Revascularization: Fifty Years of Revascularization: Where Are We and Where Are We Heading?

    NARCIS (Netherlands)

    F. Costa (Francesco); S. Ariotti (Sara); M. Valgimigli (Marco); P.H. Kolh (Philippe); S. Windecker (Stephan)

    2015-01-01

    textabstractThe joint European Society of Cardiology and European Association of Cardio-Thoracic Surgery (ESC/EACTS) guidelines on myocardial revascularization collect and summarize the evidence regarding decision-making, diagnostics, and therapeutics in various clinical scenarios of coronary artery

  12. Wie Effektiv ist Microteaching? Ein Uberblick uber funfundreifsig Jahre Forschung (How Effective Is Micro-Teaching? A Survey of Fifty-Three Years of Research).

    Science.gov (United States)

    Klinzing, Hans Gerhard

    2002-01-01

    Reviews 200+ studies on microteaching. Argues that the use of microteaching in pre- and inservice education leads to positive and long-term effects in the acquisition of verbal and non-verbal behaviorial patterns, integration of learning into individual behavioral repertoire, and in the transfer into professional teaching practice. (CAJ)

  13. Ginzburg deserved Nobel prize 50 years back

    CERN Multimedia

    Golovchansky, V

    2003-01-01

    "Vitali Ginzburg deserved a Nobel prize fifty years back, Leonid Keldysh, academician of the Russian Academy of Sciences, who was Ginzburg's disciple, told Tass. "The Ginzburg-Landau phenomenal theory of superconductivity deserved a Nobel prize right upon being produced. It was a work of intransient importance" (1/2 page).

  14. Irish Accents, Foreign Voices: Mediated Agency and Authenticity in In the Name of the Father and Fifty Dead Men Walking

    Directory of Open Access Journals (Sweden)

    Nicole Ives-Allison

    2013-06-01

    Full Text Available Given the intensity of narrative contestation over the public history of and discourse around the modern period of Northern Irish civil conflict known locally as ‘the Troubles’, for filmmakers from outside of Northern Ireland to be seen as making a legitimate contribution to existing debates, there is a pressure for their film texts to be read as ‘authentic’. This desire for authenticity fundamentally shapes the narrative approach taken by these filmmakers. Various filmmaking strategies have been employed in the pursuit of authenticity, but both Jim Sheridan’s In the Name of the Father (1993 and Kari Skogland’s Fifty Dead Men Walking (2008 have taken a distinctly narrative approach, relying upon local written autobiographical material. However, the way in which Sheridan and Skogland have sought to deploy the authenticity embedded in locally grounded source material flirts with self-defeatism as both films problematically obscure the limitations on agency imposed by the filmmakers on the local voices upon who claims of authenticity, and thus the films’ legitimacy, depend.

  15. No baby booms or birth sex ratio changes following Fifty Shades of Grey in the United States.

    Science.gov (United States)

    Grech, Victor

    2017-07-01

    The Fifty Shades of Grey (FSOG) trilogy were publicised by the media as inflaming increased coital activity, and that this would result a baby boom. Furthermore, increased coital activity skews the sex ratio at birth (M/T) toward male births. This study was carried out in order to ascertain whether there were any spikes in total births or in M/T in the United States (US) circa nine months following the FSOG books. Monthly male and female births for the US were obtained directly from the website of the Centre for Disease Control (01/2007-12/2015). This study analysed 36,499,163 live births (M/T 0.5117, 95% CI 0.5116-0.5119). There are no discernible spikes in total births or M/T at annual level, or circa nine months after FSOG book releases i.e. 04/2012 and 01/2013. The absence of spikes in births or M/T may have been due to exaggeration of the FSOG effect, it may only have provoked planned pregnancies, or modern contraception was sufficiently effective to prevent extra conceptions. The media build-up may also have stimulated a Hawthorne effect, with FSOG-affected individuals employing effective contraception. This study highlights the importance of measurement of cause and effect since anticipated results may not always ensue from events. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Random Walk Investigation in Indian Market with special reference to S&P Nifty – Fifty Stocks.

    Directory of Open Access Journals (Sweden)

    Tamilselvan M Manickam

    2015-10-01

    Full Text Available The competence of a financial system is entirely depending upon the stock market efficiency. The gradual growth of equity investor’s participation is inevitable to enrich the overall growth of emerging economies.Hence the necessity is felt to provide an empirical support to the investing community. For the purpose, this study attempts to examine the weak-form efficiency of Indian stock market – National Stock Exchange (NSE. The study has used the daily closing price of the Nifty fiftystocks from 3rdJanuary 2011 to 24thApril 2015. To test the weak form efficiency both parametric and non-parametric tests called Autocorrelation, Augmented Dicky Fuller test, and Runs Test were performed.  The study reveals that 39 stocks of NSE-Nifty Fifty are found to be weak form inefficient, so that the investors can formulate trading strategies to gain abnormal returns. The Index and 10 stocks are found to be weak form efficient during the study period since the price series found to be autocorrelation existence.Key words: Time Series - Auto Correlation – Unit Root Test – Random Walk– Stationary – National Stock Exchange

  17. Physical chemical and citotoxic evaluation of highly diluted solutions of Euphorbia tirucalli L. prepared through the fifty milesimal homeopathic method

    Directory of Open Access Journals (Sweden)

    Carlos Renato Zacharias

    2010-07-01

    Full Text Available Background: although Hahnemann described the fifty-milesimal (LM method in the 6th edition of the Organon of the Medical Art, very little research has been carried out on the physical chemical properties of these homeopathic preparations. Furthermore, there is still no evidence allowing for the correlation between the alleged physical chemical properties and the biological effects of high dilutions. Aims: to evaluate physical chemical characteristics of LM preparations including electrical conductivity, pH and refraction index, and their effect on biological experimental models. Materials and methods: preparations tested for physical chemical analysis were dilutions 1 lm to 10 lm of Euphorbia tirucalli L. prepared from the latex and the juice of the plant. To rule the seasonal characteristics of this plant, 2 different populations were used, one collected in June 2007 and the other in May 2008. Furthermore, the cytotoxic effect of Euphorbia tirucalli 5 lm was tested on human breast cancer cells (MCF7 through MTT assay. Some differences among the two collections were observed. However, any clear correlation could be observed between physical chemical properties and biological activity.

  18. One hundred and fifty-seven cases of knee osteoarthritis treated by electroacupuncture%电针治疗膝关节骨性关节炎157例

    Institute of Scientific and Technical Information of China (English)

    霍则军; LIU Xuan

    2011-01-01

    Knee osteoarthritis (KOA) is manifested by pain,rigidity and functional disturbance of the knee joints,regarded as a kind of retrograde disease.It affects the health and life quality of the patients.One hundred and fifty-seven cases of KOA have been treated by electroacupuncture since 2005.The report is as follows.

  19. Analyzing Social Issues Related to Teaching about the Federal Budget, Federal Debt, and Budget Deficit in Fifty State High School Social Studies Standards

    Science.gov (United States)

    Marri, Anand R.; Crocco, Margaret S.; Shuttleworth, Jay; Gaudelli, William; Grolnick, Maureen

    2012-01-01

    This study of all fifty state, high school social studies curriculum standards found a lack of attention in the vast majority of state standards to the federal budget, federal debt, and budget deficit, topics of significant concern. These concepts are important to teaching about economics in the United States since they lie at the center of…

  20. Years Follow-Up

    Directory of Open Access Journals (Sweden)

    Atooshe Rohani

    2013-05-01

    Full Text Available   Inroduction: Heart failure (HF is an important cause of morbidity and mortality in the cases of Beta-thalassemia major. The purpose of this study was to estimate HF prevalence in these patients and to assess the survivability of those who were treated with intensive chelating therapy.   Design and methods: This cross sectional study included 72 beta-thalassemia major cases, the mean age at the time of referral was 15.7±6.2 years (range 6-35 years and were followed in a prospective 2 year study. A self-reporting symptom questionnaire was administered, a 12-lead ECG was taken and an echocardiography was obtained from all participants. Echocardiography was performed at 6 month intervals or when a new symptom developed. Results: Risk factors (except for iron overload in the study population were hypothyroidism and diabetes mellitus. The male to female ratio was0.75.Twelve patients had left ventricular (LV systolic dysfunction and 57,79% had LV diastolic dysfunction whereas 11,15% had RV failure. Fifty-nine (81% patients had cardiac disease of which diastolic dysfunction was the most common manifestation .Those with systolic dysfunction were older at presentation (22 ± 6 years versus 31 ± 4 years; P

  1. Valedictory Editorial: The past six years.

    Science.gov (United States)

    Lennon, Michael A

    2016-12-01

    Fifty years ago this month I graduated from the University of Liverpool. A few months earlier, along with three friends, I had driven overland to attend the International Dental Students Congress held that year in Israel. On the way we drove the spectacular road from Beirut up to Damascus, visited Petra in the Southern Jordanian desert, at that time devoid of tourists, viewed the Chagall windows in the synagogue on the Hadassah University Medical campus, and listened to the world cup final with a group of German students in a youth hostel overlooking the Mandelbaum Gate. Little did we know that within twelve months these beautiful countries and their kind people would be plunged into war and that this conflict and chaos would continue to haunt this region, almost unabated, for the next fifty years. Copyright© 2016 Dennis Barber Ltd.

  2. Hur sexualiteten konstrueras i webbartiklar om filmen Fifty Shades of Grey : En foucauldiansk diskursanalys om hur den normala sexualiteten görs

    OpenAIRE

    Thörner, Kim

    2015-01-01

    This qualitative study aims to study how sexuality is constructed in web articles on the movie Fifty Shades of Grey. The study is based on a social constructivist perspective where language is seen as constitutive of reality. The study is based on a Foucauldian discourse analysis which is used in order to see what is excluded and included in the articles’ construction of normal sexuality. The result shows that there are similarities in how the web articles produce normal sexuality. Firstly, s...

  3. 50 years of personal memories

    CERN Multimedia

    2004-01-01

    The official book for CERN's 50th anniversary will be available as from the Open Day on 16 October. This beautiful book of about 250 pages tells of half a century of events and achievements at CERN through the eyes of 62 witnesses. Administrators, physicists and engineers recall both large and small events in the history of the Laboratory. This luxury edition features many magnificent photographs - often not well known - from CERN's valuable photo archive. Infinitely CERN Memories from fifty years of research Until the end of the month, the book will be sold at the special price of 50 CHF instead of 70 CHF.

  4. 50 years of personal memories

    CERN Multimedia

    2004-01-01

    http://www.cern.ch/cern50/ The official book for CERN's 50th anniversary will be available as from the Open Day on 16 October. This beautiful book of about 250 pages tells of half a century of events and achievements at CERN through the eyes of 62 witnesses. Administrators, physicists and engineers recall both large and small events in the history of the Laboratory. This luxury edition features many magnificent photographs - often not well known - from CERN's valuable photo archive. Infinitely CERN Memories from fifty years of research Until the end of the month, the book will be sold at the special price of 50 CHF instead of 70 CHF.

  5. 《五十二病方》中的巫术与民俗%Witchcraft medicine and folklore in Wushierbingfang (Prescriptions for Fifty-two Diseases)

    Institute of Scientific and Technical Information of China (English)

    贾海燕

    2010-01-01

    One important characteristic of early stage of TCM is the intermixture of witches medicine and folklore.A few witch prescriptions in Wushierbingfang (Prescriptions for Fifty -two Diseases ) indicated the residual traces of the mixture of witch and medicine in the medical literatures.The witch prescriptions recorded in Wushierbingfang( Prescriptions for Fifty-two Diseases ) could be divided into supplication,Yu-step, exorcism, Nuo ritual and peach wood charms etc.Witchcraft developed into folklore and the application of witchcraft sometimes manifested as the form of folklore, which were also reflected in the records of Wushierbingfang ( Prescriptions for Fifty-two Diseases).%巫医混杂是古代早期医学的一个重要特征.战国时期中的少量巫方的保留,正是医混杂现象在医学文献中残留的痕迹.中记载的巫方可分为祝由、禹步、祓除、傩礼、桃符等.巫同时又演变为民风民俗,术的实施常常表现民风民俗的形式,的记载对此也有一定反映.

  6. 'A Theory of the Allocation of Time' Turns Fifty: Its Impact on the Field of Health Economics.

    Science.gov (United States)

    Grossman, Michael

    2016-01-01

    The year 2015 is the 50th anniversary of the publication of 'A Theory of the Allocation of Time,' by Gary S. Becker in the 1965 volume of The Economic Journal. To mark that occasion, this editorial focuses on the importance of that paper in the history and evolution of the field of health economics. Copyright © 2015 John Wiley & Sons, Ltd.

  7. State Policies Affecting the "Adult Re-Entry Pipeline" in Postsecondary Education: Results of a Fifty-State Inventory

    Science.gov (United States)

    Boeke, Marianne; Zis, Stacey; Ewell, Peter

    2011-01-01

    With support from the Bill and Melinda Gates Foundation, the National Center for Higher Education Management Systems (NCHEMS) is engaged in a two year project centered on state policies that foster student progression and success in the "adult re-entry pipeline." The adult re-entry pipeline consists of the many alternative pathways to…

  8. Evaluation of Concordance between Hip and Spine T Scores in the Diagnosis of Osteoporosis in Men Over Age of Fifty

    Directory of Open Access Journals (Sweden)

    Oya Özdemir

    2015-12-01

    Full Text Available Objective: The aim of this study was to evaluate the concordance in diagnosis of osteoporosis based on the World Health Organization (WHO classification of bone mineral density (BMD measurements of hip and spine in men aged ≥50 years. Materials and Methods: The BMD measurements, which were measured via dual x-ray energy absorptiometry (DXA, of 10.049 patients admitted to our hospital between January 1, 2012 and August 1, 2013 were retrospectively reviewed and 649 men aged ≥50 years were included in the study. It was defined as minor discordance when the difference between two sites was no more than one WHO diagnostic class. Major discordance was present when one site is osteoporotic and the other is normal. Results: The mean age of the participants was 68.7±9.1 (50-93 years. The mean values of lumbar spine and total hip BMD values were 1.1681±0.231 (0.629-2.267 g/cm2 and 0.933±0.152 (0.414-1.444 g/cm2, respectively. According to L1-L4 vertebra T score, 54.4% of the individuals were classified as normal, 33% were osteopenic, and 12.6% were osteoporotic. Whereas, according to total femur T score 41.7% of participants were normal, 47.5% had osteopenia, and 10.8% had osteoporosis. Concordance of T scores, minor discordance, and major discordance were seen in 59.6%, 37.6%, and 2.8% of the patients, respectively. Conclusion: In this study, it was shown that in 4 of every 10 male patients aged ≥50 years tested by DXA, T score discordance between spine and total hip measurement sites is present. This ratio is similar to the results of previous studies investigating the prevalence of this phenomenon in larger samples including both postmenopausal women and men. Clinicians should keep in their mind that T score discordance is a prevalent finding and can be related to various physiological and pathological patient factors as well as the performance or analysis of DXA itself.

  9. Fifty-six cases of protrusion of lumbar intervertebral disc treated by penetration and oral administration of Chinese decoction plus traction.

    Science.gov (United States)

    Zhong, Q

    2000-12-01

    Fifty-six cases of the protrusion of the lumbar intervertebral disc in the treatment group were treated by drug-penetration and oral administration of traditional Chinese decoction plus traction, and the other 35 cases in the control group by oral administration of Chinese decoction and traction. The results showed that the cure rate in the treatment group was 83.9%, and that in the control group was 57.1%, with a statistically significant difference between the two groups (P lumbar intervertebral disc.

  10. GASTRIC OUTLET OBSTRUCTION IN PROTON PUMP INHIBITOR ERA: A PROSPECTIVE STUDY OF FIFTY CASES IN TERTIARY HOSPITAL IN SOUTH INDIA

    Directory of Open Access Journals (Sweden)

    Suresh Kumar

    2016-01-01

    ulcer with gastric outlet obstruction, males are 8 in number (67% and females are 4 in numbers (33%. A total of 184 patients were studied and only 50 were included for the study. More than two-third of patients were males. Patients with malignant gastric outlet obstruction were older than those of benign type. This difference was statistically significant (p<0.001. Gastric cancer was the commonest malignant cause of gastric outlet obstruction, whereas peptic ulcer disease was the commonest benign cause. Commonest age group for cancer antrum with gastric outlet obstruction is 51-60 years and that of chronic DU with gastric outlet obstruction is 41-50 years. For antral carcinoma, Subtotal gastrectomy with Billroth II anastomosis was done for operable patients. Palliative anterior gastrojejunostomy for inoperable patients. For chronic DU, Truncal vagotomy with short loop posterior gastrojejunostomy was done in 12 patients. CONCLUSION So with the advent of recent antiulcer drugs the commonest cause of gastric outlet obstruction is carcinoma antrum of stomach, which has compared well with other center studies. Commonest age group for carcinoma antrum with gastric outlet obstruction is 51-60 years and that of chronic DU with gastric outlet obstruction is 41-50 years. Gastric outlet obstruction in our setting is more prevalent in males and the cause is mostly malignant. The majority of patients present late with poor general condition. Early recognition of the diagnosis, aggressive resuscitation and early institution of surgical management is of paramount importance if morbidity and mortality associated with gastric outlet obstruction are to be avoided.

  11. Teaching with Documents: A Cartoonist's View of the Eisenhower Years.

    Science.gov (United States)

    Mueller, Jean West; Schamel, Wynell Burroughs

    1990-01-01

    Illustrates how to teach U.S. history through the use of original documents such as Charles Nickerson's cartoon, "Images of the Fifties from Disneyland to Suez." States that the original artwork for this cartoon, which portrays the Eisenhower years, is in the Dwight D. Eisenhower Library in Abilene, Kansas. Provides a pretest, teaching…

  12. Advancement of knowledge of Brucella over the past 50 years

    Science.gov (United States)

    Fifty years ago, bacteria in the genus Brucella were known to cause infertility and reproductive losses. The genus was considered to contain only three species, B. abortus, B. melitensis and B. suis. Since the early 1960’s, at least seven new species have been identified as belonging to the Brucell...

  13. Fifty hertz magnetic fields individually affect chromatin conformation in human lymphocytes: dependence on amplitude, temperature, and initial chromatin state.

    Science.gov (United States)

    Sarimov, Ruslan; Alipov, Eugene D; Belyaev, Igor Y

    2011-10-01

    Effects of magnetic field (MF) at 50 Hz on chromatin conformation were studied by the method of anomalous viscosity time dependence (AVTD) in human lymphocytes from two healthy donors. MF within the peak amplitude range of 5-20 µT affected chromatin conformation. These MF effects differed significantly between studied donors, and depended on magnetic flux density and initial condensation of chromatin. While the initial state of chromatin was rather stable in one donor during one calendar year of measurements, the initial condensation varied significantly in cells from another donor. Both this variation and the MF effect depended on temperature during exposure. Despite these variations, the general rule was that MF condensed the relaxed chromatin and relaxed the condensed chromatin. Thus, in this study we show that individual effects of 50 Hz MF exposure at peak amplitudes within the range of 5-20 µT may be observed in human lymphocytes in dependence on the initial state of chromatin and temperature. Copyright © 2011 Wiley-Liss, Inc.

  14. [A short history of infectious diseases since the fifties of the last century and the importance of vaccination].

    Science.gov (United States)

    Marešová, Vilma

    2015-01-01

    Vaccination in the Czech lands has a long history; it begun during the Austro-Hungarian Empire in 1803 by vaccination against smallpox, and in the late 19th century by vaccination against rabies. In the second half of the 20th century, the basic vaccination included also other vaccines. Thanks to paediatricians, vaccination coverage of children was so high that in addition to the immunity of individuals the collective immunity was also significant. The incidence of infectious diseases has dropped significantly. Today the population, both medical and lay, almost does not know the classic childrens infectious diseases or their risk of complications. This creates a feeling in recent years that vaccination is unnecessary and that it is a source of complication and, therefore, better not to vaccinate. However, diseases, except for smallpox, have not disappeared, and for the susceptible unvaccinated individuals they represent a great risk. There are now occurring at atypical age groups where their diagnosis is even not considered. Therefore, it is important to return to the course of disease as well as to the potentially serious complications in unvaccinated people.

  15. Ongoing controversies surrounding cardiac remodeling: is it black and white-or rather fifty shades of gray?

    Science.gov (United States)

    Spaich, Sebastian; Katus, Hugo A; Backs, Johannes

    2015-01-01

    Cardiac remodeling describes the heart's multimodal response to a myriad of external or intrinsic stimuli and stressors most of which are probably only incompletely elucidated to date. Over many years the signaling molecules involved in these remodeling processes have been dichotomized according to a classic antagonistic view of black and white, i.e., attributed either a solely maladaptive or entirely beneficial character. By dissecting controversies, recent developments and shifts in perspective surrounding the three major cardiac signaling molecules calcineurin (Cn), protein kinase A (PKA) and calcium/calmodulin-dependent kinase II (CaMKII), this review challenges this dualistic view and advocates the nature and dignity of each of these key mediators of cardiac remodeling as a multilayered, highly context-sensitive and sophisticated continuum that can be markedly swayed and influenced by a multitude of environmental factors and crosstalk mechanisms. Furthermore this review delineates the importance and essential contributions of degradation and proteolysis to cardiac plasticity and homeostasis and finally aims to integrate the various aspects of protein synthesis and turnover into a comprehensive picture.

  16. Ongoing controversies surrounding cardiac remodeling: is it black and white – or rather fifty shades of grey?

    Directory of Open Access Journals (Sweden)

    Sebastian eSpaich

    2015-07-01

    Full Text Available Cardiac remodeling describes the heart’s multimodal response to a myriad of external or intrinsic stimuli and stressors most of which are probably only incompletely elucidated to date. Over many years the signaling molecules involved in these remodeling processes have been dichotomized according to a classic antagonistic view of black and white, i.e. attributed either a solely maladaptive or entirely beneficial character. By dissecting controversies, recent developments and shifts in perspective surrounding the 3 major cardiac signaling molecules calcineurin (Cn, protein kinase A (PKA and calcium/calmodulin-dependent kinase II (CaMKII, this review challenges this dualistic view and advocates the nature and dignity of each of these key mediators of cardiac remodeling as a multilayered, highly context-sensitive and sophisticated continuum that can be markedly swayed and influenced by a multitude of environmental factors and crosstalk mechanisms.Furthermore this review delineates the importance and essential contributions of degradation and proteolysis to cardiac plasticity and homeostasis and finally aims to integrate the various aspects of protein synthesis and turnover into a comprehensive picture.

  17. Fifty and Over Age Group’s Perception of the Mosque and Clergy in the Context of Presentation of Religious Services

    Directory of Open Access Journals (Sweden)

    Abdullah İNCE

    2014-07-01

    Full Text Available Providing religious services is a critical subject that necessitates to consider the different informations, qualilatives and periods. The overridings of these are the religious information relies on correct sources, considering the interlocutor in presentation of this information and the qualitatives who provides religious services should possess. The one of the most importent hassle of providing religious services is the differences between the mass of interlocutor and demands of them. In this context it will be easy to provide religious services when we know the structural characteristics of mass of the interlocutor, their ideas about the provider persons and institutions and their demands. When it considered the age profile of mosque community we see that one of the most importent part i s fifty and over - fifty age group. Actually the most importent interlocutor part of this service in the content of internal mosque services is that age group. In this study it has examined this age group’s perception of “mosque” and “reverend”. Also it has mentioned the social function of mosque and reverends.

  18. Cost-effectiveness and cost-utility of a Web-based or print-delivered tailored intervention to promote physical activity among adults aged over fifty: an economic evaluation of the Active Plus intervention.

    Science.gov (United States)

    Golsteijn, Rianne Hj; Peels, Denise A; Evers, Silvia Maa; Bolman, Catherine; Mudde, Aart N; de Vries, Hein; Lechner, Lilian

    2014-09-28

    The adverse health effects of insufficient physical activity (PA) result in high costs to society. The economic burden of insufficient PA, which increases in our aging population, stresses the urgency for cost-effective interventions to promote PA among older adults. The current study provides insight in the cost-effectiveness and cost-utility of different versions of a tailored PA intervention (Active Plus) among adults aged over fifty. The intervention conditions (i.e. print-delivered basic (PB; N = 439), print-delivered environmental (PE; N = 435), Web-based basic (WB; N = 423), Web-based environmental (WE; N = 432)) and a waiting-list control group were studied in a clustered randomized controlled trial. Intervention costs were registered during the trial. Health care costs, participant costs and productivity losses were identified and compared with the intervention effects on PA (in MET-hours per week) and quality-adjusted life years (QALYs) 12 months after the start of the intervention. Cost-effectiveness ratios (ICERs) and cost-utility ratios (ICURs) were calculated per intervention condition. Non-parametric bootstrapping techniques and sensitivity analyses were performed to account for uncertainty. As a whole (i.e. the four intervention conditions together) the Active Plus intervention was found to be cost-effective. The PB-intervention (ICER = €-55/MET-hour), PE-intervention (ICER = €-94/MET-hour) and the WE-intervention (ICER = €-139/MET-hour) all resulted in higher effects on PA and lower societal costs than the control group. With regard to QALYs, the PB-intervention (ICUR = €38,120/QALY), the PE-intervention (ICUR = €405,892/QALY) and the WE-intervention (ICUR = €-47,293/QALY) were found to be cost-effective when considering a willingness-to-pay threshold of €20,000/QALY. In most cases PE had the highest probability to be cost-effective. The Active Plus intervention was found to be a cost

  19. Necroptosis: Fifty shades of RIPKs.

    Science.gov (United States)

    Ichim, Gabriel; Tait, Stephen Wg

    2015-01-01

    Apoptosis and necroptosis are 2 major, yet distinct, forms of regulated cell death. Whereas apoptosis requires caspase protease function, necroptosis requires activation of the receptor interacting protein kinases 1 (RIPK1) and RIPK3. Following activation, RIPK3 phosphorylates mixed-lineage kinase domain-like (MLKL), leading to cell death. Apoptosis and necroptosis are deeply intertwined such that a given death stimulus can often engage either form of cell death. Recent studies published in Cell Death and Differentiation by the Han, Oberst, and Vaux laboratories provide exciting new insights into necroptosis and how it interconnects with apoptosis. As we will discuss, their findings address key questions including: How does a cell choose between apoptosis or necroptosis? How can RIPK3 also induce apoptosis? What is the nature of the RIPK1-3 signaling cascade leading to necroptosis? Finally, data from the Oberst and Han groups strongly argue that RIPK1 is not only involved in executing necroptosis, but also protects against this process in some settings.

  20. Fostering First-Year Students' Engagement and Well-Being through Visual Narratives

    Science.gov (United States)

    Everett, Michele C.

    2017-01-01

    This article reports on a qualitative study that explored the learning outcomes from an innovative instructional method, visual narratives, used in a first-year seminar. Fifty-three students enrolled in a mandatory first semester student success course were instructed to use visual images to tell the story of the first-year experience. Data…

  1. La renovación de la arquitectura salmantina en la década de los cincuenta = Salamanca’s architecture renewal during the Fifties

    Directory of Open Access Journals (Sweden)

    Sara Núñez Izquierdo

    2015-01-01

    Full Text Available Este artículo da a conocer la relevancia de una buena parte del desconocido patrimonio arquitectónico salmantino de la década de 1950. Finalizada la Guerra Civil, el objetivo de la arquitectura se concentró en la reconstrucción y dignificación del país a base de un estilo historicista anacrónico, que fue remitiendo a finales de la década de 1940. Este fue el caso de Salamanca, ciudad en la que la renovación arquitectónica se dio en las tipologías religiosa, doméstica e industrial. Las nuevas obras proyectadas en Madrid se erigieron rápidamente como los modelos a seguir, de las que tuvieron noticia los técnicos bien por conocimiento directo o bien a través de las numerosas publicaciones que se promovieron desde el Estado. Aquellas constituyeron un indudable estímulo y favorecieron el viraje hacia la modernidad, a la que se dio en llamar la «Nueva Arquitectura». Tras el análisis del corpus salmantino, resulta fácil demostrar la voluntad de renovación con la que fue proyectado, así como la distinción de notables ejemplos objeto de estudio, de los que se incorpora referencias archivísticas, hemerográficas y gráficas.This paper offers a view of the importance of Salamanca’s architecture during the Fifties. The situation in Spain in the aftermath of the Civil War change the orientation of the Spanish architecture, so that during the Fifties Salamanca redefined religious, housing and industrial architectural models. Publications were crucial for spreading the modern models but also travelling and studying the buildings in big cities like Madrid. Having this reference, the architects that worked in Salamanca knew how to change from historical design to modern one that are worth to study. The aim of this work is also give detailed newspapers, graphic and archive’s documentation that will show the importance of the architectural heritage of the city of Salamanca in that period.

  2. Characterization and evaluation of washability of Alaskan coals: Fifty selected seams from various coal fields: Final technical report, September 30, 1976-February 28, 1986. [50 coal seams

    Energy Technology Data Exchange (ETDEWEB)

    Rao, P.D.

    1986-09-01

    This final report is the result of a study initiated in 1976 to obtain washability data for Alaskan coals, to supplement the efforts of the US Department of Energy in their ongoing studies on washability of US coals. Washability characteristics were determined for fifty coal samples from the Northern Alaska, Chicago Creek, Unalakleet, Nenana, Matanuska, Beluga, Yentna and Herendeen Bay coal fields. The raw coal was crushed to 1-1/2 inches, 3/8 inch, 14 mesh and 65 mesh top sizes, and float-sink separations were made at 1.30, 1.40 and 1.60 specific gravities. A limited number of samples were also crushed to 200 and 325 mesh sizes prior to float-sink testing. Samples crushed to 65 mesh top size were also separated at 1.60 specific gravity and the float and sink products were characterized for proximate and ultimate analyses, ash composition and ash fusibility. 72 refs., 79 figs., 57 tabs.

  3. Teacher evaluation as a policy target for improved student learning: A fifty-state review of statute and regulatory action since NCLB.

    Directory of Open Access Journals (Sweden)

    Helen M. Hazi

    2009-03-01

    Full Text Available This paper reports on the analysis of state statutes and department of education regulations in fifty states for changes in teacher evaluation in use since the passage of No Child Left Behind Act of 2001. We asked what the policy activity for teacher evaluation is in state statutes and department of education regulations, how these changes in statutes and regulations might affect the practice of teacher evaluation, and what were the implications for instructional supervision from these policy actions. Teacher evaluation statutes and department of education regulations provided the data for this study, using archival records from each state's legislature and education departments that were placed into a comparison matrix based on criteria developed from the National Governors Association (NGA goals for school reform (Goldrick, 2002. Data were analyzed deductively in terms of these criteria for underlying theories of action (Malen, 2005, trends, and likely effects on teacher evaluation and implications for supervision. The majority of states adopted many of the NGA strategies, asserted oversight and involvement in local teacher evaluation practices, decreased the frequency of veteran teacher evaluation, and increased the types of data used in evaluation. Whether or not the changes in teacher evaluation will improve student learning in the long run remains to be seen.

  4. Geologic Exploration of the Planets: The First 50 Years

    Science.gov (United States)

    Carr, Michael H.

    2013-01-01

    Fifty years ago, on 14 December 1962, the Mariner 2 spacecraft flew by Venus and inaugurated the modern era of planetary exploration. Since that first Venus flyby, roughly 80 spacecraft have successfully probed, orbited, flown by, landed on, or roved on other planets, satellites, asteroids, and comets. As Carl Sagan used to say, only one generation of humankind can be the first explorers of the solar system, and we are that generation.

  5. 1957-2007: 50 Years of Higher Order Programming Languages

    OpenAIRE

    Alen Lovrenčić; Mario Konecki; Tihomir Orehovački

    2009-01-01

    Fifty years ago one of the greatest breakthroughs in computer programming and in the history of computers happened -- the appearance of FORTRAN, the first higher-order programming language. From that time until now hundreds of programming languages were invented, different programming paradigms were defined, all with the main goal to make computer programming easier and closer to as many people as possible. Many battles were fought among scientists as well as among developers around concepts ...

  6. Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years after Initial Diagnosis

    Science.gov (United States)

    Gillberg, I. Carina; Helles, Adam; Billstedt, Eva; Gillberg, Christopher

    2016-01-01

    We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13-26 years). Only three of the 50 men had "never" met criteria for an additional psychiatric/neurodevelopmental diagnosis and…

  7. Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years after Initial Diagnosis

    Science.gov (United States)

    Gillberg, I. Carina; Helles, Adam; Billstedt, Eva; Gillberg, Christopher

    2016-01-01

    We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13-26 years). Only three of the 50 men had "never" met criteria for an additional psychiatric/neurodevelopmental diagnosis and…

  8. Intranasal LH-RH treatment of cryptorchidism. A clinical trial and 5 years follow-up

    DEFF Research Database (Denmark)

    Thorup, Jørgen Mogens; Mauritzen, K; Skakkebaek, N E

    1987-01-01

    The effect of intranasal LH-RH on cryptorchidism was investigated in 45 prepubertal boys with 68 undescended testes. A daily dose of 1.2 mg LH-RH was given for 4 weeks. A total of 16 testes (24%) descended. Follow-up examination 5 years later showed that relapse had occurred in two cases. Fifty-t...

  9. Functional status and dependency of stroke patients 5 years after clinical rehabilitation

    NARCIS (Netherlands)

    Dekker, R.; Arendzen, J.H.; Eisma, W.H.

    1995-01-01

    Objectives. A population of stroke patients is described five years after discharge from a rehabilitation centre. The aim of the study was to obtain insight in a) long-term changes in functional capacities; b) disability and the perceived problems; and c) the sort of help needed. Methods. Fifty

  10. Evaluating the Role of Writing in the First and Second Year University Foreign Language Curriculum

    Science.gov (United States)

    Hubert, Michael D.

    2014-01-01

    Approaches to foreign language (FL) instruction have changed a great deal in the past fifty years, the most fundamental change being the shift from a focus solely on language form to a focus on communicative competence (CC). Although most FL instructors now appear to focus on CC in the teaching of speaking, they do not necessarily apply CC to…

  11. Vaticano II, cincuenta años después (Vatican II, fifty years later) - DOI: 10.5752/P.2175-5841.2011v9n24p1207

    OpenAIRE

    José Comblin

    2012-01-01

    ResumenEl artículo parte de una situación que tendrá gran importancia para la posterior evolución del Concilio en la Iglesia: la existencia de una minoría conciliar conservadora, representada por la Curia Romana, estratégicamente presente en las comisiones preparatorias. De las tensiones entre renovadores y conservadores, resultaron documentos ambiguos, anunciando temas nuevos, a los que se contraponían viejas facetas de la tradición papal. Paralelamente a lo que el Concilio representó en tér...

  12. Vaticano II, cincuenta años después (Vatican II, fifty years later - DOI: 10.5752/P.2175-5841.2011v9n24p1207

    Directory of Open Access Journals (Sweden)

    José Comblin

    2012-01-01

    Full Text Available ResumenEl artículo parte de una situación que tendrá gran importancia para la posterior evolución del Concilio en la Iglesia: la existencia de una minoría conciliar conservadora, representada por la Curia Romana, estratégicamente presente en las comisiones preparatorias. De las tensiones entre renovadores y conservadores, resultaron documentos ambiguos, anunciando temas nuevos, a los que se contraponían viejas facetas de la tradición papal. Paralelamente a lo que el Concilio representó en términos de renovación de la Iglesia, el artículo traza el perfil de otro cambio ocurrido en la historia do Occidente: la revolución cultural, simbólicamente representada por 1968. Esta significó la crítica radical a todas las instituciones establecidas y de todos los sistemas de autoridad. Con relación a la Iglesia, la revolución cultural (marcada, entre otras cosas, por el descubrimiento de la píldora anticonceptiva y por la explosión feminista puso en jaque sus dogmas y valores. Concomitantemente, los cambios en el modo de producción capitalista caminaban en dirección a la desvalorización del trabajo y a la exacerbación del consumo. En crisis y desprestigiada por el  impacto de los cambios culturales, la Iglesia reaccionó con el “retorno a la grande disciplina”. En América Latina, donde la recepción del Concilio prometía frutos auspiciosos, quedan tímidas reformas. Frente a todo esto, la reflexión propuesta por el artículo señala caminos de esperanza para la vivencia de la fe.Palabras Clave: Iglesia. Concilio Vaticano II. Curia Romano. Revolución cultural. 1968. AbstractThis article starts from a situation of great importance in the subsequent evolution of the Council within the Church: the existence of conservative minority represented by the Roman Curia, strategically present within the preparatory commissions. Tensions between reformers and conservatives led to ambiguous documents and announced new issues to which the papal tradition was opposed. Next to the Council represented in terms of renewal of the Church, the article traces the profile of another change that took place in Western history: the Cultural Revolution represented symbolically by 1968. The revolution meant a radical critique of all established institutions, and all systems of authority. The Cultural Revolution (marked by the discovery of the pill and the feminist explosion also put into question the dogmas and values of the Church. Concomitantly, changes in the capitalist mode of production devaluated the work and encouraged consumption. In crisis and discredited by the impact of cultural changes, the Church responded with a “return to the great discipline”. In Latin America, where the reception of the Council promised auspicious fruits, timid reforms remained. Given this, the reflection proposed by the article points out the way of hope for living the faith.Keywords: Church. Vatican II. Roman Curia. Cultural Revolution. 1968.- DOI: 10.5752/P.2175-5841.2011v9n24p1207

  13. CIENTO CINCUENTA AÑOS DE PENSAMIENTO COEVOLUTIVO: LA VIDA ES UNA MARAÑA DE INTERACCIONES One Hundred and Fifty Years of Coevolutionary Thinking: Life is a Web of Interactions

    Directory of Open Access Journals (Sweden)

    ENRIQUE TORRES

    Full Text Available La supervivencia y reproducción de la inmensa mayoría de organismos multicelulares dependen de interacciones ecológicas, frecuentemente especializadas, con organismos de otras especies. La coevolución, entendida como el conjunto de cambios evolutivos recíprocos entre especies que ejercen estas interacciones, se reconoce como un proceso continuo que organiza la variabilidad darviniana en complejas redes biológicas. Esta visión dinámica suaviza el conflicto entre la naturaleza armónica de Humboldt y la naturaleza en guerra de Darwin y otros naturalistas del siglo 19. Los cimientos conceptuales de la biología coevolutiva incluyen el papel causal de los microorganismos en las enfermedades, la ubicuidad de las simbiosis, su frecuente caracter especialista y la determinación mendeliana de los desenlaces de tales interacciones. En tanto que son el resultado de la selección natural, los cambios coevolutivos afectan los rasgos hereditarios involucrados en las respectivas interacciones. Como las especies están constituidas por poblaciones genéticamente diversas y estructuradas espacialmente, la coevolución entre dos o más especies dadas puede hacer que estos cambios coevolutivos sean cualitativa o cuantitativamente diferenciales según la localidad, originando mosaicos geográficos. La biología coevolutiva busca construir una atalaya conceptual que amarre la selección natural darviniana con la ecología. Esta nueva perspectiva permite avizorar la compleja maraña de la vida, y comprender que para conservar las especies es necesario conservar sus interacciones. En este artículo se examina la coevolución desde sus raíces darvinianas, pasando por la identificación de los elementos teóricos indispensables para su formulación, hasta llegar a su interpretación actual.Multicellular organisms require one or more coevolved ecological interactions to survive and reproduce. Coevolution, the set of reciprocal evolutionary changes between these interacting species, is a continuous process that organizes Darwinian diversity in complex biological webs. This dynamic vision tempers the conflict between Humboldt's harmonious Nature and the warring Nature held by Darwin and other 19th century naturalists. The conceptual foundations of coevolutionary biology include the germ theory of disease, the ubiquity of symbioses, their frequent feature as specialized interactions, and the Mendelian determination of their outcomes. Those coevolutionary changes, driven ultimately by natural selection, affect hereditary traits involved in the interactions. Since species consist of genetically diverse populations with geographic structure, coevolution between two or more given species may cause qualitative or quantitative differential trait changes according to location, giving rise to geographic mosaics. Coevolutionary biology aims at building a conceptual outlook that blends Darwinian natural selection with ecology. This new perspective allows a view of a complex web of life, which will enhance our appreciation of the importance of preserving interactions as a way to preserve species. This article examines coevolution from its Darwinian roots, through the identification of key theoretical elements essential for its formulation, and concludes with its current interpretation.

  14. O impacto das condições bucais na qualidade de vida de pessoas com cinquenta ou mais anos de vida The impact on life quality due to oral conditions in people fifty years or above

    Directory of Open Access Journals (Sweden)

    Vinicius Cappo Bianco

    2010-07-01

    Full Text Available Avaliou-se a influência de variáveis sociodemográficas e as condições bucais na qualidade de vida de 224 indivíduos, com 50 anos ou mais de Bauru (SP. Os dados foram coletados de acordo com o Oral Health Surveys-Basic Methods: índices de cárie, periodontal comunitário, perda de inserção periodontal e uso/necessidade de próteses odontológicas. A percepção do indivíduo sobre suas condições bucais, foi medida pelo Oral Health Impact Profile, com sete domínios: limitação funcional, dor, desconforto psicológico, incapacidades física, psicológica e social e desvantagem. 60% dos indivíduos eram aposentados; 42% sem atividade social; 65,5% com renda mensal de um a três salários mínimos; 53% usavam prótese total superior e, destes, 33% ambas; 1,94 dentes cariados e 5,4 restaurados; OHIP-os impactos sociais foram menos intensos que os físicos/ psicológicos; a idade foi significante em todos os domí­nios; apenas a condição periodontal foi importante para a qualidade de vida. As variáveis sociodemográficas e as condições bucais tiveram pequena variação no OHIP; os impactos sociais foram menos intensos que os físicos/psicológicos na qualidade de vida; a maioria dos entrevistados acusou pelo menos um impacto da saúde bucal na qualidade de vida; os escores do OHIP diminuíram nos grupos de maior idade.The objective of this work was to evaluate the influence of socio-demographic variables and oral health conditions in the quality of life of non-institutionalized people aged 50 or above, living in Bauru, São Paulo State. Clinical oral examinations were conducted on a sample of 224 people including dental caries, periodontal disease and usage or need of dental prosthesis according to WHO suggestions for community dental health surveys. They were also asked to answer a questionnaire comprised of 49 questions about the impact of their oral status on the activities of daily living (OHIP. Descriptive statistics and multiple regression analysis were computed with individual scores of each domain as dependent variables. The results were: 60% were retired people, 42% exercise no social activity and 65.5% earned less than three minimum wages. Dentate people had a mean of 15.3 missing teeth, 117 people (53% of the sample had full dentures. It could be concluded that regression analysis showed no socio-demographic variable but age having a significant impact on quality of life; as people get older oral disorders seems to produce lower impact on quality of life. As it concerns to oral clinical data only periodontal disease showed impact on quality of life.

  15. Remark on Opium——the Japanese Fifty Years' Drug Policy for Invading China%简评《鸦片——日本侵华毒品政策五十年(1895-1945)》

    Institute of Scientific and Technical Information of China (English)

    董文武; 张文涛

    2009-01-01

    @@ 毒品问题在近代中国是一个严重的社会问题,也是某些帝国主义国家侵略中国的险恶手段之一.是河北师范大学历史文化学院王宏斌教授继、之后,研究近代中国毒品问题的又一力作,于2005年9月由河北人民出版社出版.

  16. Fifty tumor necrosis factor-based isolated limb perfusions for limb salvage in patients older than 75 years with limb-threatening soft tissue sarcomas and other extremity tumors

    NARCIS (Netherlands)

    B. van Etten (Boudewijn); A.N. van Geel (Albert); J.H.W. de Wilt (Johannes); A.M.M. Eggermont (Alexander)

    2003-01-01

    textabstractBACKGROUND: Isolated limb perfusion (ILP) with tumor necrosis factor (TNF) and melphalan is highly effective in treating limb-threatening soft tissue sarcoma (STS) and other bulky tumors. Because of fear of TNF-associated toxicity, ILP with TNF is not offered to older p

  17. 宝山吾木村乾隆五十九年东巴文地契译释%Translation and Annotation of the Qianlong Fifty-ninth Year Dongba Title Deed in Baoshan Wumu Village

    Institute of Scientific and Technical Information of China (English)

    和丽峰

    2012-01-01

    地契是东巴文应用性文献的重要类别,对于研究纳西族政治经济、历史民俗、语言文字和社会关系有很高的学术价值。根据对整张地契的东巴象形文字逐字逐句地进行译释,然后按文中内容和残缺部位的大小,对所缺部位进行推断填充,从而使整张地契达到阅读的顺畅与内容的完整。%Title deed which is an important type of Dongba applied document has high academic value in the research of politics,economy,history,folklore,linguistics and social relation of Naxi nationality.Dongba hieroglyphs on the title deed were translated and annotated,then the missing parts were inferred and filled so as to smooth the reading and complete the contents.

  18. The Fifty Years of Chemical Power Sources in China(Ⅲ)--Nickel Series Batteries%中国化学电源50年(3)--镍系列电池

    Institute of Scientific and Technical Information of China (English)

    夏熙

    2000-01-01

    The development in chemical power sources of a series of nickel batteries including manufacture, technologies, performance, theories and battery materials, such as nickel hydroxide, cadmium hydroxide, various hydrogen storage alloys and the same for cadmium nickel batteries and metal hydride- nickel batteries during 1978~1998 in China were studied.%介绍了我国镍系列电池的研究进展,包括镉/镍与金属氢化物/镍电池的正负极材料、性能、制造以及理论。

  19. Simultaneous onset of Alzheimer's disease in a husband and wife in their mid-fifties: what do we really know about environmental factors?

    Science.gov (United States)

    Pelcovits, Ari; Marriotti, Rachel; Heath, Jonathan; Perry, George; Castellani, Rudy J

    2015-01-01

    Environmental factors can play a role in the pathogenesis of Alzheimer's disease. We present a case of the simultaneous onset of Alzheimer's disease in two middle aged adults. A married couple ages 54 year and 51-year-old female cohabiting together were diagnosed with Alzheimer's disease within the same year. The patient's both developed cognitive decline shortly after a major renovation of their property and followed a similar disease course. The diagnosis was supported by clinical presentation and tissue pathology on autopsy. Environmental factors may play a role in the pathogenesis of Alzheimer's disease. Further understanding of the disease cascade is required.

  20. Past Years

    Science.gov (United States)

    Lodge, Oliver

    2012-07-01

    Preface; 1. Ancestry and early days; 2. Schooldays; 3. Relation with other boys at school; 4. Education; 5. Influence of the Royal Institution; 6. Later education in London; 7. Reminiscences of Bedford College; 8. Scientific work and friends in London; 9. Personal retrospect; 10. Romance; 11. Influence of the British Association; 12. Reminiscences of Coopers Hill and assistants and popular lectures; 13. Liverpool; 14. Scientific work at Liverpool; 15. Scientific work at Liverpool (cont.); 16. Scientific work at Liverpool (cont.); 17. Electric waves and the beginnings of wireless; 18. Other friends; 19. Family life; 20. Holidays; 21. Side issues; 22. Early experiences in psychical research; 23. Psychical research; 24. Further psychic adventures, and psycho-physical phenomena; 25. Reminiscences of my years at the university of Birmingham; 26. Birmingham friendships and recollections; 27. Scientific retrospect; 28. Apologia pro vita mea; Index.

  1. 50 DUBO tips. Fifty practical tips for healthier and environment consciousness building, housing, working and living; 50 DUBO tips. Vijftig praktische tips om gezonder en milieubewuster te bouwen, wonen, werken en te leven

    Energy Technology Data Exchange (ETDEWEB)

    Haas, M.; Cassiers, B.; Weichler, I.; Vermeulen, M.; Bellens, G.; Thoelen, P. (eds.)

    2003-07-01

    Fifty tips with respect to energy conservation, sustainability and health are presented for builders and consumers who plan to build or retrofit houses. [Dutch] Dit boekje bevat 50 DUBO-tips voor bouwprofessionals en consumenten die gaan (ver)bouwen. Op beknopte wijze wordt per thema een serie tips gegeven die een gezonde, milieuvriendelijke en kostenbesparende woning garanderen. De thema's die aan bod komen zijn; de initiatief- en ontwerpfase, gezondheid, ruimte en omgeving, materialen, energie en water.

  2. Cumulative incidence and treatment of non-simultaneous bilateral femoral neck fractures in a cohort of one thousand two hundred and fifty patients.

    NARCIS (Netherlands)

    Burgers, P.T.; Zielinski, S.M.; Mailuhu, A.K.; Heetveld, M.J.; Verhofstad, M.H.J.; Roukema, G.R.; Patka, P.; Poolman, R.W.; Lieshout, E.M. van; Biert, J.

    2014-01-01

    PURPOSE: In the Netherlands, over 20,000 patients sustain a hip fracture yearly. A first hip fracture is a risk factor for a second, contralateral fracture. Data on the similarity of the treatment of bilateral femoral neck fractures is only scarcely available. The objectives of this study were to

  3. Cumulative incidence and treatment of non-simultaneous bilateral femoral neck fractures in a cohort of one thousand two hundred and fifty patients

    NARCIS (Netherlands)

    P.T.P.W. Burgers (Paul); S.M. Zielinski (Stephanie); A.K.E. Mailuhu (Adinda); M.J. Heetveld (Martin); M.H.J. Verhofstad (Michiel); G.R. Roukema (Gert); P. Patka (Peter); R.W. Poolman (Rudolf); E.M.M. van Lieshout (Esther)

    2014-01-01

    textabstractPurpose In the Netherlands, over 20,000 patients sustain a hip fracture yearly. A first hip fracture is a risk factor for a second, contralateral fracture. Data on the similarity of the treatment of bilateral femoral neck fractures is only scarcely available. The objectives of this study

  4. Oscillator Phase Noise: A 50-Year Review.

    Science.gov (United States)

    Leeson, David B

    2016-08-01

    Fifty years ago emerging requirements in oscillator applications led to the 1964 IEEE-NASA Symposium on Short-term Frequency Stability. Following that, IEEE Technical Committee 14.7 was established to unify time- and frequency-domain definitions of frequency stability. I had the good fortune to participate and contribute as a member of the symposium program committee and the IEEE committee. This paper is a personal retrospective of events that are said to have shaped our field: the 1964 Symposium, the 1966 Proc. IEEE special issue on frequency stability we edited (with comments on my oscillator-model paper), and our 1971 paper, "Characterization of Frequency Stability," written as a basis for IEEE STD 1139.

  5. Pathways of Sleep, Affect, and Stress Constellations during the First Year of College: Transition Difficulties of Emerging Adults

    Science.gov (United States)

    Ari, Lilac Lev; Shulman, Shmuel

    2012-01-01

    One hundred and fifty Israeli first-year college students were assessed twice: during the first semester following the commencement of their undergraduate studies and toward the end of the second semester. At each semester, participants completed web-based daily diaries for seven consecutive days assessing daily sleep, affective mood, stress, and…

  6. The Use of Discourse Markers in Paragraph Writings: The Case of Preparatory Year Program Students in Qassim University

    Science.gov (United States)

    Daif-Allah, Ayman Sabry; Albesher, Khaled

    2013-01-01

    The purpose of this paper is to identify the discourse markers used by Saudi EFL learners in their paragraph writing. The study was conducted on fifty students of the Preparatory Year Program at Qassim University. Data were collected from one hundred paragraphs written by the students at the end of the first and second semesters of the academic…

  7. Hard and soft tissue imaging of the temporomandibular joint 30 years after diagnosis of osteoarthrosis and internal derangement

    NARCIS (Netherlands)

    deLeeuw, R; Boering, G; vanderKuijl, B; Stegenga, B

    1996-01-01

    Purpose: This article describes the clinical and imaging findings in the temporomandibular joints (TMJs) of patients 30 years after the initial diagnosis of osteoarthrosis and internal derangement. Patients and Methods: Fifty-five TMJs with a history of osteoarthrosis and internal derangement and 37

  8. Australian Children with Special Health Care Needs: Social-Emotional and Learning Competencies in the Early Years

    Science.gov (United States)

    Whiteford, Chrystal; Walker, Sue; Berthelsen, Donna

    2013-01-01

    This study examined the relationship between special health care needs and social-emotional and learning competence in the early years, reporting on two waves of data from the Kindergarten Cohort of "Growing up in Australia: The Longitudinal Study of Australian Children" (LSAC). Six hundred and fifty children were identified through the…

  9. Does Federal Financial Aid Policy Influence the Institutional Aid Policies of Four-Year Colleges and Universities? An Exploratory Analysis

    Science.gov (United States)

    Hossler, Don; Kwon, Jihye

    2015-01-01

    There is a dearth of empirical work that examines the relationships between federal financial aid policy and institutional financial aid priorities and expenditures. This study uses Resource Dependency Theory to explore whether changes the amount of financial aid awarded by colleges and universities during the last fifty years are best explained…

  10. Maxillary overdentures supported by four or six implants in the anterior region : 5-year results from a randomized controlled trial

    NARCIS (Netherlands)

    Slot, Wim; Raghoebar, Gerry M.; Cune, Marco S.; Vissink, Arjan; Meijer, Henny J. A.

    2016-01-01

    Objective: To compare a four-and six-implant maxillary overdenture after an observation period of 5 years. Material and methods: Fifty subjects with functional problems concerning their maxillary denture, who had ample bone volume in the anterior region to place four or six implants, were included a

  11. If the universe is teeming with aliens where is everybody? fifty solutions to the Fermi paradox and the problem of extraterrestrial life

    CERN Document Server

    Webb, Stephen

    2002-01-01

    Given the fact that there are perhaps 400 million stars in our Galaxy alone, and perhaps 400 million galaxies in the Universe, it stands to reason that somewhere out there, in the 14-billion-year-old cosmos, there is or once was a civilization at least as advanced as our own. The sheer enormities of the numbers almost demand that we accept the truth of this hypothesis. Why, then, have we encountered no evidence, no messages, no artifacts of these extraterrestrials? Webb discusses in detail the 50 most cogent and intriguing solutions to Fermi's famous paradox: If the numbers strongly point to the existence of extraterrestrial civilizations, why have we found no evidence of them?

  12. Ionic charge, radius, and potential control root/soil concentration ratios of fifty cationic elements in the organic horizon of a beech (Fagus sylvatica) forest podzol.

    Science.gov (United States)

    Tyler, Germund

    2004-08-15

    The root/organic soil concentration ratio; R/S) of 50 cationic mineral elements was related to their ionic properties, including ionic radius (r), ionic charge (z), and ionic potential (z/r or z2/r). The materials studied were ectomycorrhizal beech (Fagus sylvatica L.) roots and their almost purely organic soil substrate, the O-horizon (mor; raw humus) of a Podzol in South Sweden, developed in a site which has been untouched by forestry or other mechanical disturbance since at least 50 years and located in an area with no local sources of pollution. Elements determined by ICP-AES were aluminium, barium, calcium, iron, potassium, magnesium, manganese, sodium and strontium. Determined by ICP-MS were silver, beryllium, bismuth, cadmium, cerium, cobalt, chromium, caesium, copper, dysprosium, erbium, europium, gallium, gadolinium, hafnium, mercury, holmium, indium, lanthanum, lithium, lutetium, niobium, neodymium, nickel, lead, praseodymium, rubidium, scandium, samarium, tin, terbium, thorium, titanium, thallium, thulium, uranium, vanadium, yttrium, ytterbium, zinc and zirconium. The R/S ratios were most clearly related to the ionic potential of the cationic elements studied, which accounted for approximately 60% of the variability in R/S among elements. The ionic charge of an element was more important than the ionic radius. Elements with high ionic charge had low R/S ratios and vice versa. No clear differences in R/S between essential and non-essential plant nutrients were observed, especially when ions of similar charge were compared.

  13. Transplantation With Livers From Deceased Donors Older Than 75 Years

    DEFF Research Database (Denmark)

    Thorsen, Trygve; Aandahl, Einar Martin; Bennet, William

    2015-01-01

    BACKGROUND: The availability of donor organs limits the number of patients in need who are offered liver transplantation. Measures to expand the donor pool are crucial to prevent on-list mortality. The aim of this study was to evaluate the use of livers from deceased donors who were older than 75...... years. METHODS: Fifty-four patients who received a first liver transplant (D75 group) from 2001 to 2011 were included. Donor and recipient data were collected from the Nordic Liver Transplant Registry and medical records. The outcome was compared with a control group of 54 patients who received a liver...

  14. Luttinger model the first 50 years and some new directions

    CERN Document Server

    Mattis, Daniel C

    2014-01-01

    The Luttinger Model is the only model of many-fermion physics with legitimate claims to be both exactly and completely solvable. In several respects it plays the same role in many-body theory as does the 2D Ising model in statistical physics. Interest in the Luttinger model has increased steadily ever since its introduction half a century ago. The present volume starts with reprints of the seminal papers in which it was originally introduced and solved, and continues with several contributions setting out the landscape of the principal advances of the last fifty years and of prominent new dire

  15. Inflammatory abdominal aortic aneurysms. A 20-year experience.

    Science.gov (United States)

    Dalainas, I; Nano, G; Ranucci, M; Bianchi, P; Stegher, S; Casana, R; Malacrida, G; Tealdi, D G

    2007-06-01

    The aim of the study was to report a 20-year single Institution experience, with the early and late outcomes of surgical treatment of inflammatory abdominal aortic aneurysms. In a 20-year period, 2 275 consecutive patients underwent elective surgical repair for non-rupture abdominal aortic aneurysm. Fifty-two patients (2.3%) were classified as inflammatory abdominal aortic aneurysms. Early and late outcomes were analyzed. One patient died in the perioperative period, giving a mortality rate of 1.92%. One patient died from a pseudoaneurysm rupture 7 months after operation. Three patients developed an aortic pseudoaneurysm in the follow-up period (mean 12.1 years, range 1-20 years) and underwent a redo operation. Overall surgical outcome of these patients, in terms of short-term and long-term is good. A high rate of pseudoaneurysm formation was observed.

  16. Thirty years of medical surveillance in perfluooctanoic acid production workers.

    Science.gov (United States)

    Costa, Giovanni; Sartori, Samantha; Consonni, Dario

    2009-03-01

    To report health outcomes of 30 years (1978-2007) of medical surveillance of workers engaged in a perfluooctanoic acid (PFOA) production plant. Fifty-three males workers (20 to 63 years) were submitted every year to medical examination and blood chemical chemistry tests, and serum PFOA dosage. In the latest survey PFOA serum levels ranged from 0.20 to 47.04 microg/mL in currently exposed workers, and from 0.53 to 18.66 microg/mL in those formerly exposed. No clinical evidence of any specific trouble or disease has been recorded over the 30 years, and all the biochemical parameters, including liver, kidney and hormonal functions, turned out to be within the reference ranges, but a significant association of total cholesterol and uric acid with and PFOA serum level was evidenced. A probable interference of PFOA on intermediate metabolism deserves further investigations.

  17. Twenty Years of Evolutionary Change in the Department of Defense’s Civil Support Mission

    Science.gov (United States)

    2013-05-23

    should include the foregoing statement.) ii ABSTRACT TWENTY YEARS OF EVOLUTIONARY CHANGE IN THE DEPARTMENT OF DEFENSE’S... gasping for air flooded television and print outlets across the globe. The casualty figures from the attack included twelve dead, fifty four...Biological Incident Response Force, II Marine Expeditionary Force, Indian Head, MD,” Marines: The Official Website of the United States Marine Corps

  18. Active Galactic Nuclei and Quasars: Why Still a Puzzle after 50 years?

    CERN Document Server

    Antonucci, Robert

    2015-01-01

    The first part of this article is a historical and physical introduction to quasars and their close cousins, called Active Galactic Nuclei (AGN). In the second part, I argue that our progress in understanding them has been unsatisfactory and in fact somewhat illusory since their discovery fifty years ago, and that much of the reason is a pervasive lack of critical thinking in the research community. It would be very surprising if other fields do not suffer similar failings.

  19. Relationships between Perceptual-Motor Skills and Postural Balance in Nine Years Old Boys

    Science.gov (United States)

    Atilgan, Oya Erkut

    2012-01-01

    The aim of this study is to investigate relationship between static-dynamic balance performance and two-hand coordination, reaction time, anthropometric measurements and leg strength. Fifty voluntary male children (age: 9.29 plus or minus 1.11 years, height: 138.86 plus or minus 7.86 cm, weight: 35.20 plus or minus 9.2 kg) who did not exercise…

  20. 50 Years of synchrotrons Adams' Memorial lecture

    CERN Document Server

    Lawson, J D; CERN. Geneva

    1996-01-01

    Fifty years ago Frank Goward of the Atomic Energy Research Establishment Group at Malvern converted a small American betatron to make the worldÕs first synchrotron. At the same time Marcus Oliphant was planning to build at Birmingham a large proton machine with a ring magnet and variable magnetic field. Ideas for this had come to him during night-shifts tending the electromagnetic separators at Oak Ridge during the war. Some seven years later, in 1953, a group gathered together in Geneva to build the PS. A major contributor to the design work which had made this possible was John Adams. An account of some of the achievements in these eventful years will be presented. CERN has built nine synchrotrons/colliders and two temporary test rings. Eight machines are still running. The review will start with the PS, the first proton synchrotron based on the alternating gradient principle invented in 1952 at BNL. The design work of the PS team, under the enlightened leadership of J.B. Adams, and the construction of the...

  1. The association between malaria parasitaemia, erythrocyte polymorphisms, malnutrition and anaemia in children less than 10 years in Senegal

    DEFF Research Database (Denmark)

    Tine, Roger C K; Ndiaye, Magatte; Hansson, Helle Holm;

    2012-01-01

    -talassaemia.RESULTS:Three hundred and fifty two children 5 years (aOR=0.03, 95%CI0.01-0.08]). Stratified by age group, anaemia was significantly associated with stunting in children less than 5 years (aOR=3.1 95%CI1.4 -- 6.8]), with, sickle cell disorders (aOR=3.5 95%CI 1.4 -- 9.0]), alpha-thalassemia (or=2.4 95%CI1...

  2. ONE HUNDRED YEARS OF MILES’ OPERATION- WHAT HAS CHANGED?

    Directory of Open Access Journals (Sweden)

    Vanja Pecić

    2008-12-01

    Full Text Available Lisfranc was probably the first to excise the rectum for cancer. He performed operation using perineal approach in 1826. This operation came into common use fifty years later. Czerny did the first combined abdominoperineal resection in attempt to finish excision he could not complete from below. Some fifteen years later Ernest Miles described the planned, one stage abdominoperineal resection.Miles name has become a synonym for this combined procedure, creating a radical change in the philosophy of resection and en bloc lymphadenectomy.In the beginning of twenty-century abdominoperineal resection became golden standard in the treatment of rectal cancer. Reconstructive operations, introduction of stapling devices and better understanding of potential tumor spread, reduced indications for Miles operation.Surgical treatment of rectal cancer made progress in the past 100 years. Miles was the first in line. Without his theory of perirectal lymphatic spread recurrence rate would be still as high as 95%.

  3. Fifty million Frenchmen have few nuclear fears

    Energy Technology Data Exchange (ETDEWEB)

    DuPont, R.L.

    A psychiatrist examines why France chose the nuclear power option in 1974 and expects for it to generate 75% of its power by 1990 in contrast to the US rejection and fear of nuclear power. The fear dominating US media coverage since 1968 is classic phobic thinking. A comparison of US and French attitudes reveals that French nuclear plants are tourist attractions, accepted by residents as both safe and of economic benefit. Accidents are examined realistically in France without the what if drama given to US incidents. Some political problems have developed and recent anti-nuclear activities are taken seriously, but the opposition was not based on fear. Public acceptance in France is partly due to a lack of energy alternatives and a pragmatism that works against phobias. (DCK)

  4. Thermodynamic Data for Fifty Reference Elements

    Science.gov (United States)

    1993-01-01

    75.302 446.353 377.005 301.352 421.833 305.508 5900 6000 75.302 453.183 378.271 302.624 429.363 306.710 6000 ISO 16 TAgLE 11.8. TmE~wODYP4AC RUNCTIOW...207.826 200 298.15 29,378 8.680 205.149 176.036 0.000 205.1󈧵 298.15 300 29.388 8.734 205.331 176.216 0.054 205. ISO 300 400 30.115 11.706 213.875...Temp. [K] Temp. [K) Original Data for Ar Coef Data for Ar0 40 4• bd 35 7 25 7 o 1 33 7 I*= 13333 1lŚ 0oO 0 "n an i m1 . Temp. [K] Temp. (K] Pipou .wn

  5. Novel Tests of Gravity Below Fifty Microns

    Science.gov (United States)

    Johnson, Jeremy; Martinez, Gabriela; Guerrero, Ian; Dunkley, Noah; Sanchez, Anthony; Isachsen, Hilde; Shaw, Duncan; Hoyle, C. D.

    2017-01-01

    Theories which attempt to unify the Standard Model and General Relativity often include features which violate the Weak Equivalence Principle (WEP) and gravitational Inverse-Square Law (ISL). A violation of either the WEP or ISL at any length scale would bring into question our fundamental understanding of gravity. Motivated by these considerations, undergraduates and faculty at Humboldt State University are building an experiment to probe gravitational interactions below the 50-micron length scale. The experiment employs a torsion pendulum with equal masses of different material arranged as a ``composition dipole.'' We measure the twist of the torsion pendulum as an attractor mass is oscillated nearby in a parallel-plate configuration, providing a time varying torque on the pendulum. The size and distance dependence of the torque variation will provide a means to determine any deviation from the WEP or ISL at untested scales. PHY-1065697, PHY-1306783, and PHY-1606988.

  6. Learned helplessness at fifty: Insights from neuroscience.

    Science.gov (United States)

    Maier, Steven F; Seligman, Martin E P

    2016-07-01

    Learned helplessness, the failure to escape shock induced by uncontrollable aversive events, was discovered half a century ago. Seligman and Maier (1967) theorized that animals learned that outcomes were independent of their responses-that nothing they did mattered-and that this learning undermined trying to escape. The mechanism of learned helplessness is now very well-charted biologically, and the original theory got it backward. Passivity in response to shock is not learned. It is the default, unlearned response to prolonged aversive events and it is mediated by the serotonergic activity of the dorsal raphe nucleus, which in turn inhibits escape. This passivity can be overcome by learning control, with the activity of the medial prefrontal cortex, which subserves the detection of control leading to the automatic inhibition of the dorsal raphe nucleus. So animals learn that they can control aversive events, but the passive failure to learn to escape is an unlearned reaction to prolonged aversive stimulation. In addition, alterations of the ventromedial prefrontal cortex-dorsal raphe pathway can come to subserve the expectation of control. We speculate that default passivity and the compensating detection and expectation of control may have substantial implications for how to treat depression. (PsycINFO Database Record

  7. Mesiodens: a retrospective study of fifty teeth.

    Science.gov (United States)

    Roychoudhury, A; Gupta, Y; Parkash, H

    2000-12-01

    A retrospective study of 30 cases of mesiodens is presented. male preponderance of 1.5:1. was 64% mesiodens were impacted and 36% erupted. Inverted impacted mesiodens was seen in 62.5% of the impacted mesiodens. 66.6% cases had 2 mesiodens per case. The harmful effects on the dentition were mostly crowding, rotation, diastema and impacted permanent incisor.

  8. Nutrition After Fifty: Tips and Recipes

    Science.gov (United States)

    ... R ITU E T S E E for ARCH Nutrition after 50 Tips and Recipes Healthy Living for ... AICR continues: Funding research on the relationship of nutrition, physical activity and weight management to cancer risk ...

  9. Incidence of peri-implant mucositis and peri-implantitis in edentulous patients with an implant-retained mandibular overdenture during a 10-year follow-up period

    NARCIS (Netherlands)

    Meijer, Henny J. A.; Raghoebar, Gerry M.; de Waal, Yvonne C. M.; Vissink, Arjan

    2014-01-01

    Objectives: The aim of this sub-analysis of two prospective studies was to assess the incidence of peri-implant mucositis and peri-implantitis in fully edentulous patients with an implant-retained mandibular overdenture during a 10-year follow-up period. Material and Methods: One hundred and fifty

  10. Cumulative live birth rates following lVF in 41-to 43-year-old women presenting with favourable ovarian reserve characteristics

    NARCIS (Netherlands)

    van Disseldorp, J.; Eijkemans, M. J. C.; Klinkert, E. R.; Velde, E. R. te; Fauser, B. C.; Broekmans, F. J. M.

    For women aged 41-43 years old, success rates in IVF are generally poor. This study aimed to assess cumulative live birth rate related to treatment costs over a maximum of three IVF cycles in selected women who were considered to still have adequate ovarian reserve. Fifty-five patients (38% of the

  11. Health care in patients 1 year post-stroke in general practice : research on the utilisation of the Dutch Transmural Protocol transient ischaemic attack/cerebrovascular accident

    NARCIS (Netherlands)

    de Weerd, L.; Rutgers, A.W.F.; Groenier, K.H.; van der Meer, K.

    2012-01-01

    This study evaluates the kind of aftercare that ischaemic stroke patients receive and the extent that aftercare fulfils the criteria of the 'Dutch Transmural Protocol transient ischaemic attack/cerebrovascular accident'. Fifty-seven patients were interviewed 1 year post-stroke about secondary

  12. 中国罐疗法溯源——《五十二病方》角法研究%Source of cupping therapy-research on Jiao method in Prescriptions for Fifty-two Kinds of Diseases

    Institute of Scientific and Technical Information of China (English)

    陈泽林

    2013-01-01

    考证了角法概念的提出,为《马王堆汉墓帛书——五十二病方》以下简称《五十二病方》;论述了《五十二病方·牡痔》中关于“以小角角之,如熟二斗米顷,而张角”的内涵,认为:“小角”是角法的工具;“角之”是触抵牡痔,表示小角的操作方式与操作部位;“如熟二斗米顷”包含角法的吸拔方法与操作时间:用煮热角法吸拔,吸拔约半个时辰(60 min);“张角”表示取罐时要用一定的力,因角内有负压.指出:《五十二病方》“以小角角之,如熟二斗米顷,而张角”,其内涵上包含使用工具、操作部位、吸拔方法、吸拔时间,符合罐疗法的4个要素.《五十二病方》的角法是现代罐疗的最早记载.%This paper aims to illustrate the meaning of the expression in the chapter Hemorrhoid in Prescriptions for Fifty-two Kinds of Diseases,in which "the horn is used for cupping and retaining the cupping there for a time for cooking two Dou of rice" and finally removed the cupping forcefully because of a high pressure in it. It holds that the expression shows the facility for Jiao Fa,cupping therapy,which is called "Xiao Jiao",Zhang Jiao made by the horn of ox,sheep,and deer. Jiao in the word of "Jiao Zhi" serves as a verb,which means cupping or touch. The manipulation and retaining time are also indicated by the vivid description of "cooking two Dou of rice". Zhang in the word of "Zhang Jiao" points out that removing the cupping should be finished forcefully. This paper also displays that the hemorrhoid treated by cupping therapy in Prescriptions for Fifty-two Kinds of Diseases refers to the external hemorrhoid. Prescriptions for Fifty-two Kind of Diseases describes the Jiao Fa,cupping therapy,in the following aspects: cupping facility,body part for cupping,manipulation and retaining time,which are the earliest record for cupping.

  13. Forty years of training program in the JAERI

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This report is to compile the past training program of researchers, engineers and regulatory members at the NuTEC (Nuclear Technology and Education Center) of Japan Atomic Energy Research Institute and the past basic seminars for the public, in addition to advice and perspective on the future program from relevant experts, in commemoration of the forty years of the NuTEC. It covers the past five years of educational courses and seminars in utilization of radioisotopes and nuclear energy for domestic and for international training provided at Tokyo and Tokai Education Centers and covers the activity of the Asia-Pacific nuclear technology transfer, including the activity of various committees and meetings. Especially, fifty six experts and authorities have contributed to the report with positive advice and perspective on the training program in the 21st century based on their reminiscences. (author)

  14. Verbal memory decline is less frequent at 10 years than at 2 years after temporal lobe surgery for epilepsy.

    Science.gov (United States)

    Andersson-Roswall, Lena; Malmgren, Kristina; Engman, Elisabeth; Samuelsson, Hans

    2012-08-01

    We investigated individual short- and long-term verbal memory changes after temporal lobe resection for epilepsy. Fifty-one patients (23 operated on the speech-dominant temporal lobe, DTL and 28 on the non-dominant temporal lobe, NDTL) were tested on learning/immediate recall and delayed recall of word-list and word-pairs preoperatively, 2 years postoperatively and 10years postoperatively. Changes were defined using reliable change indices of 23 healthy controls assessed at corresponding intervals. Fewer patients had reliable declines at 10 years than at 2 years (DTL: 13-35% vs 35-44%; NDTL: 0-4% vs 7-21%). Four DTL patients (17%) had reliable declines in ≥2 tests at 10-year follow-up. More NDTL patients had improvement at 10 years than at 2 years (18-30% vs 4-22%). The only risk factor for decline both short and long term was DTL resection. In conclusion, most patients had stable verbal memory postoperatively. A few DTL patients had a lasting decline at long-term follow-up, but more patients showed partial recovery, especially in the NDTL group.

  15. Fifty-Five years of Pediatric Endocrinology and 50 years of the Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases in Slovenia / 55 Let Pediatrične Endokrinologije in 50 Let Kliničnega Oddelka Za Endokrinologijo, Diabetes in Presnovne Bolezni Pediatrične Klinike

    Directory of Open Access Journals (Sweden)

    Battelino Tadej

    2015-03-01

    Full Text Available Pediatrična endokrinologija je začela s svojim neodvisnim razvojem zgodaj v splošnem razvoju te specilanosti, z izrazitim poudarkom na raziskovalnemu delu in klinični odličnosti. Slovenska pediatrična endokrinologija je bila že od začetkov evropske pediatrične endokrinologije njen sestavni del, še posebej kot soustanoviteljica prve mednarodne skupine ‘International Study Group for Diabetes in Children and Adolescents’. Po pionirskem delu prof. dr. Leva Matajca je prof. dr. Ciril Kržišnik KO za endokrinologijo, diabetes in bolezni presnove Pediatrične klinike v Ljubljani trdno vpel v mednarodno znanstveno skupnost. V zadnjem desetletju KO sodeluje pri vrhunskem raziskovalnem delu in zagotavlja klinično oskrbo po najvišjih mednarodnih standardih.

  16. International Cooperation for the next 50 years: The International Project on Innovative Reactors and Fuel Cycles (INPRO)

    Energy Technology Data Exchange (ETDEWEB)

    Kupitz, J.; Steur, R.; Depisch, F. [IAEA, Wagramerstrasse 5, PF 100, 1400 Vienna (Austria)]. e-mail: J.Kupitz@iaea.org

    2004-07-01

    During the last fifty years remarkable results are achieved in the application of nuclear technology for the production of electricity. Looking ahead to the next fifty years it is clear that the demand for energy will grow considerably and also the requirements for the way the energy will be supplied. Within INPRO the future of the energy demand and supply was explored and several scenario's identified. A leading requirement for energy supply is coming up and will play a crucial role: sustainability of the way the energy supply will be realized. Fulfilling the growing need for energy in developing countries is as well an important issue. Based on these scenario's for the next fifty years, an inventory of requirements for the future of nuclear energy systems has been collected as well a methodology developed by INPRO to assess innovative nuclear systems and fuel cycles. On the base of this assessment, the need for innovations and breakthroughs in existing technology can be defined. To facilitate the deployment of innovative nuclear systems also the infrastructure, technical as well institutional has to be adjusted to the anticipated changes in the world such as the globalization. As a contribution to the conference the main messages of INPRO will be presented. (Author)

  17. 51例石油作业习惯性流产女性淋巴细胞遗传损伤研究%Study on the lymphocytes cytogenetic damage of fifty-one habitual abortion women in petroleum operations

    Institute of Scientific and Technical Information of China (English)

    慕明涛; 霍满鹏; 蒲力群; 张静; 刘俊俊

    2013-01-01

    Objective:Analysis of the impact of sister chromatid exchange (SCE) in peripheral blood lymphocytes among habitual abortion women in the petroleum operations.Methods:Fifty-one women with habitual abortion and 20 normal women with childbearing age were selected randomly as observation group and control group respectively.The peripheral blood lymphocytes from them were cultivated and detected by SCE test method,and count the frequency of them.Results:The frequency of SCE was 8.62 ±0.75,it's frequency in observation group were higher than that in control group (P < 0.05).Conclusion:The incidence of SCE can be used as the detective index of chromosome's structural stability of women with habitual abortions who are exposed to the environment in petroleum operations of certain hazardous substances which can results in DNA damage.%目的 分析石油作业女性习惯性流产与淋巴细胞姐妹染色单体互换(SCE)的关系.方法 随机选择习惯性流产的石油作业女性51人和正常的育龄女性20人,检测其外周血淋巴细胞姐妹染色单体互换,记数SCE发生率.结果 观察组的外周血淋巴细胞SCE发生率为8.62±0.75,明显高于对照组(P<0.05).结论 SCE的发生可作为石油作业习惯性流产女性染色体结构稳定性的检测指标.石油作业环境中的某些有害物质可造成女性细胞遗传损伤.

  18. 2008: transition year and crucial year!

    CERN Multimedia

    Association du personnel

    2008-01-01

    The year 2008 will be an important, even crucial year for the Organization and its staff. Indeed, the start-up of the LHC will mark the beginning of a fascinating period for the physics community and, more generally, for basic science in Europe and the world. All eyes of this community will be focused on the CERN site in Geneva. It is essential that we are able, all together, to successfully pass this milestone to enter the LHC era, thus crowning over a decade of hard work of all staff concerned.

  19. Happy New Year

    Institute of Scientific and Technical Information of China (English)

    姚婷

    2008-01-01

    As part of the the Chinese New Year celebration, people buy presents, decorations, special foods and new clothing. Railroad stations throughout China are filled with travelers who take their vacation days around New Year to return home for a family

  20. Five Extraordinary Years

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    THE Hong Kong Special Administrative Regionis now five years old. These have been fiveextraordinary and innovative years, duringwhich the concept of "one country, two sys-tems" advocated by Deng Xiaoping has become a

  1. Translational control of protein synthesis: the early years.

    Science.gov (United States)

    Lodish, Harvey F

    2012-10-19

    For the past fifty-five years, much of my research has focused on the function and biogenesis of red blood cells, including the cloning and study of many membrane proteins such as glucose and anion transporters and the erythropoietin receptor. We have also elucidated the mechanisms of membrane insertion, folding, and maturation of many plasma membrane and secreted proteins. Despite all of this work and more, I remain extremely proud of our very early work on the regulation of mRNA translation: work on bacteriophage f2 RNA in the 1960s and on translation of α- and β-globin mRNAs in the early 1970s. Using techniques hopelessly antiquated by today's standards, we correctly elucidated many important aspects of translational control, and I thought readers would be interested in learning how we did these experiments.

  2. Mariner 2 and its Legacy: 50 Years on

    CERN Document Server

    Bailey, Jeremy

    2013-01-01

    Fifty years ago, NASA's Jet Propulsion Laboratory (JPL) built and flew the first successful spacecraft to another planet: Mariner 2 to Venus. This paper discusses the context of this mission at a crucial phase in the space race between the USA and USSR and its results and legacy. As its first major success, Mariner 2 helped to cement JPL's position as a centre for robotic planetary exploration. Mariner 2 successfully solved the scientific problem of the high temperature observed for Venus by ground-based radio telescopes. It also pioneered new techniques for observing the atmosphere of a planet from space, which were subsequently developed into the microwave sounding and infrared sounding techniques for observing the Earth atmosphere. Today these techniques provide some of the most important data for constraining weather forecasting models, as well as a key series of data on the Earth's changing climate.

  3. Occupational fluorosis through 50 years: clinical and epidemiological experiences

    Energy Technology Data Exchange (ETDEWEB)

    Grandjean, P.

    1982-01-01

    Fifty years ago, in 1932, skeletal fluorosis was discovered as an occupational disease in cryolite workers in Copenhagen, Denmark. Following the initial reports, new cases were identified in other industries, such as the production of aluminum and superphosphate fertilizer. In light cases of fluorosis, the bone changes are often associated with nonspecific joint and muscle pains, but the disease may be entirely asymptomatic. The fluoride-induced osteosclerosis seems to be reversible, but the long-term significance of fluoride accumulation in the body is not known. Family cases of dental fluorosis have been occurred in long-term residents near fluoride-emitting industries, and in hot areas with high, natural fluoride levels in the drinking water. Skeletal fluorosis has only played a minor role in the discussion concerning fluoridation of drinking water, however. Changing and increasing uses of fluorides have led to a renewed interest in this occupational disease.

  4. Ten Years of Abstinence in Former Opiate Addicts: Medication-Free Non-Patients Compared to Methadone Maintenance Patients.

    Science.gov (United States)

    Peles, Einat; Sason, Anat; Tene, Oren; Domany, Yoav; Schreiber, Shaul; Adelson, Miriam

    2015-01-01

    Fifty-five former opioid addicts who have been methadone maintained patients for 10 or more years and whose urine has tested negative for drugs for 2 or more years were compared to 99 former opioid addicts who have been medication-free for 10 or more years. Groups were comparable in age and education, but the medication-free subjects were younger when having started opioids with more severe addiction scores. Methadone maintained patients presented with a higher proportion of psychiatric comorbidity and chronic pain. Their scores of perceived sleep quality and cognitive state were poorer than the medication-free individuals. Possible explanations of the differences are discussed in this article.

  5. 50 Years of ``Scaling'' Jack Kilby's Invention

    Science.gov (United States)

    Doering, Robert

    2008-03-01

    This year is the 50th anniversary of Jack Kilby's 1958 invention of the integrated circuit (IC), for which he won the 2000 Nobel Prize in Physics. Since that invention in a laboratory at Texas Instruments, IC components have been continuously miniaturized, which has resulted in exponential improvement trends in their performance, energy efficiency, and cost per function. These improvements have created a semiconductor industry that has grown to over 250B in annual sales. The process of reducing integrated-circuit component size and associated parameters in a coordinated fashion is traditionally called ``feature-size scaling.'' Kilby's original circuit had active (transistor) and passive (resistor, capacitor) components with dimensions of a few millimeters. Today, the minimum feature sizes on integrated circuits are less than 30 nanometers for patterned line widths and down to about one nanometer for film thicknesses. Thus, we have achieved about five orders of magnitude in linear-dimension scaling over the past fifty years, which has resulted in about ten orders of magnitude increase in the density of IC components, a representation of ``Moore's Law.'' As IC features are approaching atomic dimensions, increasing emphasis is now being given to the parallel effort of further diversifying the types of components in integrated circuits. This is called ``functional scaling'' and ``more then Moore.'' Of course, the enablers for both types of scaling have been developed at many laboratories around the world. This talk will review a few of the highlights in scaling and its applications from R&D projects at Texas Instruments.

  6. Western New Year

    Institute of Scientific and Technical Information of China (English)

    康俊民

    2006-01-01

    @@ There is one-day holiday in most countries on New Year's Day. The real celebrations for New Year happen on the night before-on New Year's Eve. There are several interesting customs in the West, and there are many differences from country to country.

  7. 1957-2007: 50 Years of Higher Order Programming Languages

    Directory of Open Access Journals (Sweden)

    Alen Lovrenčić

    2009-06-01

    Full Text Available Fifty years ago one of the greatest breakthroughs in computer programming and in the history of computers happened -- the appearance of FORTRAN, the first higher-order programming language. From that time until now hundreds of programming languages were invented, different programming paradigms were defined, all with the main goal to make computer programming easier and closer to as many people as possible. Many battles were fought among scientists as well as among developers around concepts of programming, programming languages and paradigms. It can be said that programming paradigms and programming languages were very often a trigger for many changes and improvements in computer science as well as in computer industry. Definitely, computer programming is one of the cornerstones of computer science.Today there are many tools that give a help in the process of programming, but there is still a programming tasks that can be solved only manually. Therefore, programming is still one of the most creative parts of interaction with computers.Programmers should chose programming language in accordance to task they have to solve, but very often, they chose it in accordance to their personal preferences, their beliefs and many other subjective reasons.Nevertheless, the market of programming languages can be merciless to languages as history was merciless to some people, even whole nations. Programming languages and developers get born, live and die leaving more or less tracks and successors, and not always the best survives. The history of programming languages is closely connected to the history of computers and computer science itself. Every single thing from one of them has its reflexions onto the other. This paper gives a short overview of last fifty years of computer programming and computer programming languages, but also gives many ideas that influenced other aspects of computer science. Particularly, programming paradigms are described, their

  8. [Clinical features of uveitis in childhood during the past 20 years].

    Science.gov (United States)

    Fujioka, S; Nakagawa, Y; Tada, R; Ohji, M; Hara, Y; Hagihara, M; Fujii, S; Haruta, Y; Yuasa, T

    1990-08-01

    One hundred and fifty five cases (237 eyes) of children with uveitis were clinically observed in the past 20 years. There was no fluctuation in the number of patients during the period. Concerning the age as the first visit, the smallest group was under 4 years of age and the numbers of patients increased at ages 14 and 15. Chief complaints usually corresponded to the age of the cases. Cases with anterior uveitis accounted for 25% of all cases, intermediate uveitis 12%, posterior uveitis 45% and panuveitis consisted of 17% of all cases, respectively. In the course of treatment, improvement of visual acuity was not statistically significant; the visual prognosis of cases affected under age 7 years was relatively poor. At the time of final observation, the visual acuity of cases, who had first visited during the past 10 years, were better than those who presented during the previous decade. Uveitis had healed or improved in 68% of cases treated in our clinic. As complications, band-shaped keratopathy was seen in 8% of the patients, cataract in 22% and glaucoma in 5%, respectively. Thirty two per cent of the cases received systemic steroid therapy and the average duration was 3.8 months. Fifty two operations were performed in 30 cases (19%), 37 eyes (16%); 16 were cataract operations and 24 were operations for glaucoma.

  9. Yangliuqing New Year Pictures

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    HANGING up New Yearpictures during khe SpringFestival to symbolize goodluck in the coming year has longbeen a tradition in China,The pic-tures are both colorful and jubilantin theme and composition so as toattract everything good in the com-ing year and drive away evil.Four main“schools” of folk artdealing with New Year pictures ex-ist.Among the best known is thewoodblocK print from Yangliuqing,

  10. The Rationality of Revolt and Fanon’s Relevance, 50 Years Later

    OpenAIRE

    Gibson, Nigel C.

    2015-01-01

    What does it mean to speak of Fanon’s relevance fifty years after his death? I suggest that one element to consider might be an epistemological challenge signaled by social movements of the wretched of the earth. Fanon’s wretched of the earth is not a story of wretchedness and suffering but of self-fashioning movements which through action become aware of themselves as subjects as they become aware of the betrayals of the leaders who speak in their name. The challenge to university-trained in...

  11. CT five years after myelographic diagnosis of lumbar disk herniation

    Energy Technology Data Exchange (ETDEWEB)

    Hurme, M.; Katevuo, K.; Nykvist, F.; Aalto, T.; Alaranta, H.; Einola, S. (Turku Univ. Central Hospital (Finland). Dept. of Surgery Turku Univ. Central Hospital (Finland). Dept. of Diagnostic Radiology Social Insurance Inst., Turku (Finland). Rehabilitation Research Centre)

    1991-07-01

    Fifty-seven patients were examined with CT 5 years after primary myelography for disabling sciatica and suspected herniated lumbar disk. Forty were in an operated group, 22 with good and 18 with poor results evaluated by occupational handicap (21) 5 years after surgery. Seventeen patients had myelography indicating disk herniation, but were treated conservatively, 9 with good and 8 with poor result. Various spinal dimensions measured at CT did not correlate with outcome. Operated patients had narrower canals than others, and male canals were broader than those in females. Increased amount of scar tissue at L4 level correlated with poor result (p=0.008). Operated patients with poor result had more advanced lateral stenosis than those treated conservatively (p<0.001). Patients with good result after operation had more degeneration observed on CT of erector spinae muscle than those treated conservatively with good outcome. Only 9% of operated patients did not have muscle degeneration. A tendency for more frequent recurrent disk herniations could be ssen for conservatively treated patients. The narrowing of the spinal canal 5 years after operation did not correlate with the 5-year outcome. (orig.).

  12. Is Three Years Enough?

    Science.gov (United States)

    Waits, Bert K.; Demana, Franklin

    1988-01-01

    Argues that the college preparatory curriculum should include more than three years of mathematics. Presents data indicating that 86 percent of students with less than three years of college preparatory mathematics take remedial mathematics and relatively few students are ready to take calculus when they enter the university. (PK)

  13. Final Year Project Report

    Energy Technology Data Exchange (ETDEWEB)

    Hubsch, Tristan [Howard University

    2013-06-20

    In the last years of this eighteen-year grant project, the research efforts have focused mostly on the study of off-shell representations of supersymmetry, both on the worldline and on the world- sheet, i.e., both in supersymmetric quantum mechanics and in supersymmetric field theory in 1+1-dimensional spacetime.

  14. One Year Later

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    It has now been one year since the catastrophic 8.0-magnitude earthquake slammed Sichuan Province on May 12, 2008. At 2:28 p.m. on that terrible day, the most destructive calamity to hit China in 60 years struck

  15. 20 Years and Counting

    Science.gov (United States)

    Kuzyk, Raya

    2008-01-01

    In commemoration of the Librarian of the Year Award's 20th anniversary, this article presents brief vignettes on all 19 of the title holders. When "Library Journal" named them Librarians of the Year, these inimitable 19 (for the 20th, Norma Blake, see EJ788676) had singled themselves out as risk takers, visionaries, bulldogs, pragmatists,…

  16. An Analyses of Bicycle Accidents in Ankara: Analyses of 5 Years

    Directory of Open Access Journals (Sweden)

    Muhittin Yilmaz

    2014-12-01

    Full Text Available Aim: Bicycles are used for transportation, exercise and recreation. In this study we aimed to investigate the epidemiological, clinical and economic aspects of bicycle injuries. Material and Method: We included in the study who admitted to the Emergency Department with a bicycle accident between January 2008 and July 2012. Patient age and sex, accident pattern, presence of personal protective measures, injured body part, Glasgow Coma Scale (GCS score, Revised Trauma Score (RTS, radiological findings, requested consultations, duration of hospital stay, season of injury, and average cost rates were recorded. The study population was divided into 2 age groups as 0-14 years and over 14 years. Results: A patients were 238 (81.2% male and their mean age was 31.5±14.1 years. Fifty-five (18.8% patients were female and their mean age was 34.5±15.9 years. Males had significantly higher rate of bicycle injury (p

  17. Três versões do pragmatismo deweyano no Brasil dos anos cinqüenta Three versions of Dewey’s pragmatism in the Brazil of the fifties

    Directory of Open Access Journals (Sweden)

    Marcus Vinicius da Cunha

    1999-07-01

    pedagogical field, as if education should be subordinated to the rules of thought and to the findings of science. The text then shows that this characterization describes only one of the trends among the renewed educational ideas. Another idea, this one heavily influenced by the thinking of North-American philosopher and educator John Dewey, offers very different directions. The paper then analyzes some articles published in the fifties by the Revista Brasileira de Estudos Pedagógicos, a journal published by the National Institute of Pedagogical Studies (INEP. Such articles, written by Anísio Teixeira, João Roberto Moreira, and Luiz Alves de Mattos amongst others, translate the renewed educational ideas of the period and express the conceptions based on John Dewey’s ideas. The themes discussed by those Brazilian educators are grouped according to the following categories: democracy, freedom, socio-educational research, and educational planning. Along the analysis performed here it has been noted that the authors express different visions of the same thinker - John Dewey. This fact can be understood using the concept of "recontextualization", proposed by Basil Bernstein, according to whom the theories or philosophical conceptions suffer modifications, sometimes fundamental, as they are transformed in pedagogical discourses. At the same that this work intends to contribute to a better understanding of the presence of Dewey’s thinking in Brazil, it also points to the need of developing deeper studies about the processes of recontextualization in the educational field.

  18. Mathematics year 5 answers

    CERN Document Server

    Alexander, Serena; Poggo, Tammy

    2014-01-01

    Features the complete set of answers to the exercises in Mathematics Year 5, to save you time marking work and enable you to identify areas requiring further attention. The book includes diagrams and workings where necessary, to ensure pupils understand how to present their answers. Also available from Galore Park www.galorepark.co.uk :. - Mathematics Year 5. - Mathematics Year 6. - 11+ Maths Practice Exercises. - 11+ Maths Revision Guide. - 10-Minute Maths Tests Workbook Age 8-10. - 10-Minute Maths Tests Workbook Age 9-11. - Mental Arithmetic Workbook Age 8-10. - Mental Arithmetic Workbook Ag

  19. First year clinical tutorials: students’ learning experience

    Directory of Open Access Journals (Sweden)

    Burgess A

    2014-11-01

    Full Text Available Annette Burgess,1 Kim Oates,2 Kerry Goulston,2 Craig Mellis1 1Central Clinical School, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia; 2Sydney Medical School, The University of Sydney, Sydney, NSW, Australia Background: Bedside teaching lies at the heart of medical education. The learning environment afforded to students during clinical tutorials contributes substantially to their knowledge, thinking, and learning. Situated cognition theory posits that the depth and breadth of the students' learning experience is dependent upon the attitude of the clinical teacher, the structure of the tutorial, and the understanding of tutorial and learning objectives. This theory provides a useful framework to conceptualize how students' experience within their clinical tutorials impacts their knowledge, thinking, and learning. Methods: The study was conducted with one cohort (n=301 of students who had completed year 1 of the medical program at Sydney Medical School in 2013. All students were asked to complete a three-part questionnaire regarding their perceptions of their clinical tutor's attributes, the consistency of the tutor, and the best features of the tutorials and need for improvement. Both quantitative and qualitative data were collected and analyzed using descriptive statistics. Results: The response rate to the questionnaire was 88% (265/301. Students perceived that their tutors displayed good communication skills and enthusiasm, encouraged their learning, and were empathetic toward patients. Fifty-two percent of students reported having the same communications tutor for the entire year, and 28% reported having the same physical examination tutor for the entire year. Students would like increased patient contact, greater structure within their tutorials, and greater alignment of teaching with the curriculum. Conclusion: Situated cognition theory provides a valuable lens to view students' experience of learning within the

  20. Year 2000 awareness

    Energy Technology Data Exchange (ETDEWEB)

    Holmes, C.

    1997-11-01

    This report contains viewgraphs on the challenges business face with the year 2000 software problem. Estimates, roadmaps, virtual factory software, current awareness, and world wide web references are given.

  1. 60 Years Unforgettable

    Institute of Scientific and Technical Information of China (English)

    2014-01-01

    <正>CPAFFC President Li Xiaolin,Former President Chen Haosu and two young staff cutting the cake in celebration of the 60th anniversary of the CPAFFC at a CCTV special program 60 Years Unforgettable on May 16

  2. Happy (Chinese) New Year!

    Science.gov (United States)

    Johnson, Georgia G.

    1979-01-01

    Suggestions are made for a classroom celebration of Chinese New Year, including discussion of the Chinese calendar and customs, a short list of appropriate children's stories, and food ideas, including a recipe for fortune cookies. (SJL)

  3. Year book Australia 1986

    Energy Technology Data Exchange (ETDEWEB)

    Castles, I. (comp.)

    1986-01-01

    The Year Book is the principal reference work produced by the Central Office of the Australian Bureau of Statistics (ABS). It provides a comprehensive and detailed statistical review of all asepcts of the economy and social conditions of Australia. In addition, it contains descriptive matter dealing with Australia's history, geography, physiography, climate and meteorology, government, defence, international relations, culture and environment. The first Official Year Book was published early in 1908. This is the seventieth Year Book issued under the authority of the Commonwealth Government and follows a similar pattern to previous editions. However chapters have been revised and new material has been added. Most of the statistics contained in this volume relate to the years ended June or December 1984 to 1985. More detailed, and in most cases more recent, statistics are available in other ABS publications.

  4. Hve Years and Counting

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A war may drag on for months and years. So does the war on terror. Five years have passed since the 9/11 events changed the skyline in New York and the security and political landscape of the world. Since the war on terror was declared, achievements have been made. Afghanistan's Taliban regime was toppled. Saddam Hussein was captured and put on trial. A terrorist plot was foiled in London. But in spite of these triumphs, one cannot help wondering: Has the

  5. 100 years of superconductivity

    CERN Document Server

    Rogalla, Horst

    2011-01-01

    Even a hundred years after its discovery, superconductivity continues to bring us new surprises, from superconducting magnets used in MRI to quantum detectors in electronics. 100 Years of Superconductivity presents a comprehensive collection of topics on nearly all the subdisciplines of superconductivity. Tracing the historical developments in superconductivity, the book includes contributions from many pioneers who are responsible for important steps forward in the field.The text first discusses interesting stories of the discovery and gradual progress of theory and experimentation. Emphasizi

  6. Chinese New Year

    Institute of Scientific and Technical Information of China (English)

    王芳

    2005-01-01

    The Chinese New Year is now known as the Spnng Festival because it starts trom the beginning otspring. Though there are some sayings about its origin (起源), all agree that the word Nian, which inmodern Chinese means “year”, was originally the name of a beast (野兽) that started to eat people thenight before the beginning of a new year.

  7. [110th year Nederlands Tijdschrift voor Tandheelkunde. 2. Root canal treatment, intra-canal disinfectants and bacterial culture: past and present].

    Science.gov (United States)

    Moorer, W R; Wesselink, P R

    2003-05-01

    Fifty years ago the Dutch Journal of Dentistry published methods and opinions concerning root canal treatment. Qualitative bacterial culture, inclusion of aggressive disinfectants, as well as antibiotics and widening of the apical constriction were carried out. Nowadays, because of several reasons, these are not clinical practice anymore. Controversy over the clinical consequences of bacterial presence in tubules and in the peri-apical area prevailed in the past and seem to be prevalent once again.

  8. Mentoring for first year medical students: humanising medical education.

    Science.gov (United States)

    Bhatia, Arati; Singh, Navjeevan; Dhaliwal, Upreet

    2013-01-01

    New entrants are vulnerable to the challenges of the medical course; mentoring programmes are known to offer support. This paper evaluated the experiences of students and faculty enrolled in a new mentoring programme. After needs analysis of students and faculty, a small-group mentoring programme for new medical students was initiated. Fifty-five volunteer faculty mentors were allocated two-three students each. At year-end, feedback using an open-ended questionnaire, revealed that there was no contact in one-third of the cases; the commonest reasons cited were lack of mentee initiative, time and commitment. Supportive mentors were appreciated. Over 95% of respondents believed that mentoring was a good idea; many believed the mentee benefitted; mentors also reported improved communication and affective skills; 60 (77.0%) mentees wanted to mentor new students the following year. Thus, mentoring of first-year students by faculty was effective, when contact occurred, in making the mentee feel supported. Mentoring may be a means of honing the affective domain and humanitarian instincts of medical faculty and students.

  9. Celebrating nine years together

    Directory of Open Access Journals (Sweden)

    Martinico Giuseppe

    2017-08-01

    Full Text Available Perspectives on Federalism starts off its ninth year with this issue which gathers, as usual, a series of multi-disciplinary pieces. Almost two years have passed since we started our collaboration with De Gruyter, and our journal has since then enjoyed continued growth and has been acquiring international visibility. 2017 is going to be rich in surprises for our readers, with a wealth of interesting projects and special issues which will increase the already high standard of the journal. 2016 was also a very challenging year for scholars interested in federalism; the start of the Trump Presidency and the results of the referendum on Brexit held on 23 June 2016 are just two examples.

  10. Emergent technologies: 25 years

    Science.gov (United States)

    Rising, Hawley K.

    2013-03-01

    This paper will talk about the technologies that have been emerging over the 25 years since the Human Vision and Electronic Imaging conference began that the conference has been a part of, and that have been a part of the conference, and will look at those technologies that are emerging today, such as social networks, haptic technologies, and still emerging imaging technologies, and what we might look at for the future.Twenty-five years is a long time, and it is not without difficulty that we remember what was emerging in the late 1980s. Yet to be developed: The first commercial digital still camera was not yet on the market, although there were hand held electronic cameras. Personal computers were not displaying standardized images, and image quality was not something that could be talked about in a standardized fashion, if only because image compression algorithms were not standardized yet for several years hence. Even further away were any standards for movie compression standards, there was no personal computer even on the horizon which could display them. What became an emergent technology and filled many sessions later, image comparison and search, was not possible, nor the current emerging technology of social networks- the world wide web was still several years away. Printer technology was still devising dithers and image size manipulations which would consume many years, as would scanning technology, and image quality for both was a major issue for dithers and Fourier noise.From these humble beginnings to the current moves that are changing computing and the meaning of both electronic devices and human interaction with them, we will see a course through the changing technology that holds some features constant for many years, while others come and go.

  11. Sixty Years of Friendship

    Institute of Scientific and Technical Information of China (English)

    Liu; Gengyin

    2014-01-01

    <正>On December 2,1977,the CPAFFC held a grand reception in the Great Hall of the People to celebrate the 80th birthday of Rewi Alley,an old friend from New Zealand.Comrade Deng Xiaoping attended the reception and declared:"Tens of thousands of foreign friends have devoted themselves to the cause of Chinese revolution.Even so,rare are those like Comrade Rewi Alley,who for 50 years on end has done tremendous work for the Chinese people,in our years of difficulty and

  12. New year, old hat

    Science.gov (United States)

    American Geological Institute; American Institute of Physics; American Associationthe Advancement of Science; Carlowicz, Michael

    It is only August, but October 1 looms large on the calendar. That is the day when the 1997 fiscal year (FY ‧97) begins for the U.S. federal government, and like last year, that day might come without a budget.In a flurry of summer activity, the U.S. Congress has passed several landmark bills on welfare reform, expansion of health coverage for workers between jobs, a raise in the minimum wage, and a Safe Drinking Water Act. The House of Representatives even passed all 13 of its annual appropriations bills before Congress took its August recess.

  13. 60 Years of Impression

    Institute of Scientific and Technical Information of China (English)

    DENG Qiwei

    2009-01-01

    @@ It has been 60 years since foundation of the People's Republic of China.These 60 years,China has experienced a huge transformation,from short supply of textile and apparel to nowadays big country of it.Facing the tough time of economic crisis,China's textile and apparel industry has been carrying out adjustment and renovation in time.How to enhance independent and creative capacity,upgrade technology,and improve brands' influence,to explore a new industrialized road and achieve the goal of being a strong country of textile by 2020 as well,it still has a long way to go.

  14. Totally implantable hearing system: Five-year hearing results.

    Science.gov (United States)

    Shohet, Jack A; Kraus, Eric M; Catalano, Peter J; Toh, Elizabeth

    2017-04-13

    1) To provide long-term hearing outcome measures of a totally implantable hearing system (implant) and compare to the baseline unaided (BLU) and baseline aided (BLA) conditions, and 2) discuss relevant safety measures. Prospective, nonrandomized, multicenter, single-subject-as-own-control design. Fifty-one subjects with mild to severe sensorineural hearing loss were implanted between 2008 and 2009 and enrolled in this postmarket approval study in the setting of private and hospital-based practices. Forty-nine of these subjects completed the 5-year study, which included annual follow-ups. Primary effectiveness endpoints were speech reception threshold (SRT) and word recognition scores at 50 dB (WRS50s). Secondary effectiveness endpoints were WRSs and the Abbreviated Profile of Hearing Aid Benefit (APHAB) scores. Adverse Device Effects (ADEs) and Serious Adverse Device Effects (SADEs) reported during the study period and a comparison of bone conduction scores are submitted as safety measures. Compared to the BLA condition, 1) SRT scores were improved at every annual follow-up; 2) WRS50s were better in 49%, and the same in 41% at the 5-year follow-up; 3) WRSs were improved by 17% at the 5-year follow-up; and 4) APHAB scores were improved in most subscales at every annual follow-up. There were three SADEs in three subjects and 15 ADEs in 11 subjects. Bone conduction scores increased by 3.7 dB at the 5-year follow-up. Average battery life was 4.9 years. The implant compared favorably to the subjects' hearing aid throughout the 5-year period in all of the areas measured and was found to be safe. 2b Laryngoscope, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  15. ENLIGHT 10 year Anniversary

    CERN Multimedia

    Alvarez, Paul

    2012-01-01

    Ten years ago, in February 2002, the European Network for Light Ion Hadron Therapy (ENLIGHT) had its inaugural meeting at CERN. As a pioneering multidisciplinary network celebrates its 10th anniversary, some of the founders recall how it all started. Picture 1 : Participants at the 10th anniversary meeting of ENLIGHT at CNAO, Pavia, in September 2012.

  16. Eleventh Year Mathematics.

    Science.gov (United States)

    Buchman, Aaron; Zimmerman, Robert

    This outline for Eleventh Year Mathematics in New York adheres closely to the recommendations of The Commission of Mathematics of the College Entrance Examination Board and thus presents a unified development of certain aspects of algebra, trigonometry, and analytic geometry. Its aim is both as a terminal course in mathematics and as a solid…

  17. IREDA: ten years on

    Energy Technology Data Exchange (ETDEWEB)

    Sahai, I.M.

    1998-04-01

    The Indian Renewable Energy Development Agency has a ten-year history of promoting small hydro energy sources for many communities beyond the reach of the national grid. Sources of funding for hydro installations in India are mentioned. It is suggested that the expansion of the hydro schemes would benefit from greater co-ordination between central and state governments. (UK)

  18. Affordances: Ten Years On

    Science.gov (United States)

    Brown, Jill P.; Stillman, Gloria

    2014-01-01

    Ten years ago the construct, affordance, was rising in prominence in scholarly literature. A proliferation of different uses and meanings was evident. Beginning with its origin in the work of Gibson, we traced its development and use in various scholarly fields. This paper revisits our original question with respect to its utility in mathematics…

  19. Western New Year

    Institute of Scientific and Technical Information of China (English)

    康俊民

    2006-01-01

    There is One-day holiday in most countries on New Year's Day.The real celebrations for New Year happen on the night before-on New Year's Eve,There are several interesting customs in the West ,and there are many differences form country to country.

  20. ESO: The CERN Years

    CERN Multimedia

    Schaeffer, A

    2012-01-01

    In 1970, CERN and ESO signed a collaboration agreement for the construction of the Observatory’s first telescope. That same year, ESO’s Telescope Division and Sky Atlas laboratory settled on the CERN site in Meyrin. Let’s turn back to the beginnings of this lasting and fruitful alliance.

  1. Ten Years of CERI.

    Science.gov (United States)

    Hameyer, Uwe

    1980-01-01

    Reports on the activities of the Centre for Educational Research and Innovation (CERI) within the last 10 years and in the future. Topics include mathematics instruction, lifelong learning, environmental education at the university level, inservice and preservice education and education for the handicapped adolescent. (SA)

  2. Creativity: The Early Years

    Science.gov (United States)

    Shade, Rick; Shade, Patti Garrett

    2016-01-01

    There is a myth that some people are creative and others are not. However, all children are born creative. They love to explore, ask questions, and are incredibly imaginative. Parents are key in nurturing their child's creativity in the early years. This article offers resources and strategies parents can use at different ages and stages (newborn,…

  3. A Tumultuous Year

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    2011 sees international order in transition amid chaos While the global financial crisis continued to take a toll on societies and politics globally 2011 has been a year of relentless turmoil and chaos. What underlies these waves of turmoil is the labor pains of the birth of a new international order.

  4. 'THE FIVE ACCURSED YEARS'

    DEFF Research Database (Denmark)

    Bryld, Claus

    2007-01-01

    The subject for this paper is the question of how the Second World War has been perceived and used since that war - in Denmark, and especially in recent years, but also with a comparative view to Norway and Sweden. In addition to an outline of the development of public history regarding the war...

  5. 150 years of science

    Directory of Open Access Journals (Sweden)

    Francesca Messina

    2011-08-01

    Full Text Available This preview of the Festival della Scienza 2011 focuses on a major initiative celebrating 150 years of Italian scientific research. Run jointly by the Italian Research Council (CNR and the Associazione Festival della Scienza, the project presents outstanding achievements in various fields including neuroscience, web technologies, genetics, chemistry and much more.

  6. 7 CFR 932.19 - Crop year and fiscal year.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Crop year and fiscal year. 932.19 Section 932.19... Regulating Handling Definitions § 932.19 Crop year and fiscal year. (a) Crop year means the 12-month period... be recommended by the committee and approved by the Secretary. (b) Fiscal year means the...

  7. 60 Years of Impression

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    It has been 60 years since foundation of the People’s Republic of China. These 60 years, China has experienced a huge transformation, from short supply of textile and apparel to nowadays big country of it. Facing the tough time of economic crisis, China’s textile and apparel industry has been carrying out adjustment and renovation in time. How to enhance independent and creative capacity, upgrade technology, and improve brands’ influence, to explore a new industrialized road and achieve the goal of being a strong country of textile by 2020 as well, it still has a long way to go.But once we look back the history, we find pride and inspiration of China’s textile industry.

  8. Novice Non-Native English Teachers' Reflections on Their Teacher Education Programmes and Their First Years of Teaching (Reflexiones de profesores novatos y no nativos del inglés sobre sus programas de formación y sus primeros años de instrucción)

    Science.gov (United States)

    Akcan, Sumru

    2016-01-01

    This study investigates novice non-native English teachers' opinions about the effectiveness of their teacher education programme and the challenges during their initial years of teaching. The results of a survey administered to fifty-five novice teachers and follow-up interviews identify strengths and weaknesses in their teacher education…

  9. 捏脊配合针刺在瑞士治疗过敏性鼻炎58例%Fifty-eight cases of allergic rhinitis treated with chiropractic and acupuncture in Switzerland

    Institute of Scientific and Technical Information of China (English)

    高军; 韩景献; ZHANG Yi

    2010-01-01

    @@ Allergic rhinitis (AR) pertains to anaphylaxis in biomedicine while to the domain of "Bigiu"(鼻鼽)in Chinese medicine with the main symptoms of rhinocnesmus, sneezing, thin nasal discharge and nasal obstruction.The disease is often persistent with high ratio of recurrent attacks.Specific medicine or methods for the radical treatment are still not available.However, great progress on treatment of AR with acupuncture has been made in recent 10 years.

  10. 25 years of service

    CERN Multimedia

    2004-01-01

    On Thursday 2 December, the Director-General received the 14 staff members who began to work in 1979, CERN's 25th anniversary, and are now themselves celebrating 25 years of service at CERN. Beugnet Claude / AB Bourgeois Georges / AB Goossens Michel / IT Herzog Patrick / IT Jeanneret Jean-Bernard / AB Lacarrère Daniel / TS Mollay Robert / TS Mornacchi Giuseppe / PH Ployer Annie / DSU Remondino Vittorio / AT Stellfeld Donat / AB Taureg Hans / PH Terrier Jean-Pierre / AB Wehrle Urs / AB

  11. Fiscal Year 1982

    Science.gov (United States)

    1983-01-01

    staff continued to serve as referees for various professional journals. Papers were refereed last year for the following: 0 Management Science 0 Journal...1 DRCSM 1 DRCSM-E 1 DRCSM-W 1 DRCSM-I 1 DRC SM-P 1 DRCSM-PM 1 DRCRE 1 DRCCP 1 DRCIS 1 DRCDM 1 DRCDP 1 DRCMS 1 DRCQA Dep Chf of Staff for Logistics

  12. Ten Years of Chandra

    Science.gov (United States)

    Weisskopf, Martin C.

    2009-01-01

    We celebrated the 10-th anniversary of the Launch of the Chandra X-ray Observatory on July 13, 2009. During these 10 years data from this Great Observatory have had a profound impact on 21st century astrophysics. With its unrivaled capability to produce sub-arcsecond images, the Observatory has enabled astronomers to make new discoveries in topics as diverse as comets and cosmology. We shall review some of the highlights, discuss the current status, and future plans.

  13. JCE: 80 Years New

    Science.gov (United States)

    Moore, John W.

    2003-01-01

    Participating in the National Science, Technology, Engineering, and Mathematics Education Digital Library project is an exciting prospect for JCE. We expect to be able to make major contributions to the project and derive major benefits from participating in it. Your help in this important undertaking would be most welcome and greatly appreciated. Help us demonstrate that an 80-year-old can dance to a new tune!

  14. Twenty-Year Reunion

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    A massive earthquake measuring 7.8 on the Richter Scale struck the city of Tangshan at 3:42 a.m. on July 28, 1976. The city, which had history of well over 100 years and a population of over one million people, was left in ruins. The violent earthquake killed 242,469 people, with 164,851 people sustaining injuries, 2,652 children under 16 years of age left as orphans and 885 elderly people as widowers. Some 96 percent of the city’s buildings and houses collapsed, with a direct economic loss of 10 billion yuan. Earthquake tremors spread over a two million square kilometer area, with hundreds of millions people placed in peril by the natural disaster.The Tangshan earthquake set a record as the world’s strongest earthquake of the century. The people of Tangshan have set a new record for the rate of reconstruction accomplished over the past 20 years. The support of the People’s Liberation Army and people across the nation combined with the unyielding efforts of survivors led to the establishment of a new Ta

  15. 2011: What a year!

    CERN Multimedia

    Staff Association

    2012-01-01

    “What a year it’s been, and what a way to end it. The star of the show has been the LHC, along with its experiments, which have again turned in an Oscar-winning performance. But there has been a strong supporting cast of actors ranging from antimatter to the CLOUD experiment.” This is what the Director-General wrote to us on 20 December in his message with his wishes for the festive season. And, do not forget, the famous hyperfast neutrinos toward Gran Sasso that put CERN on the front of the world stage. These achievements which are the pride and strength of the Organization were made possible “thanks to the hard work of all CERN’s staff,” as noted by the Director-General in his New Year speech of Wednesday, January 11. He reviewed the year 2011 and set out the challenges ahead in 2012 and beyond. The scientific and technological achievements of 2011 are a great satisfaction to the Director-General, his team and all CERN staff. Moreover, despite a...

  16. Campylobacter bacteraemia: 16 years of experience in a single centre.

    Science.gov (United States)

    Hussein, Khetam; Raz-Pasteur, Ayelet; Shachor-Meyouhas, Yael; Geffen, Yuval; Oren, Ilana; Paul, Mical; Kassis, Imad

    2016-01-01

    Campylobacter bacteraemia (CB) is rare and usually occurs in immune-compromised patients. In this study we examined the incidence and epidemiology of CB in one institution over 15.5 years. The medical records of all the consecutive patients with CB admitted to our hospital from 2000 to 2015 were retrospectively reviewed. Clinical characteristics, microbiologic and outcome data were collected. During the study period, 65 patients with CB were identified. The majority of the patients were middle aged and immune-compromised. Campylobacter jejuni was the most commonly identified species (33/47, 70%). The main underlying conditions were haematological malignancies (43%) and chronic liver disease (14%). Fifty-seven percent of the patients were receiving immunosuppressive therapy at the time of bacteraemia. The most common presenting symptoms were fever (85%), diarrhoea (40%), abdominal pain (40%), and nausea and vomiting (40%). Of the isolates tested, 97% were susceptible to macrolides, and only 35% were susceptible to quinolones. Susceptibility to quinolones decreased over the years. Most patients did not receive adequate empiric antibiotic treatment (81.5%) and about 20% never received directed therapy. Mortality and relapse rates were low (5% each). There was no association between adequate empirical or definitive antibiotic therapy and adverse outcomes. The main predisposing factor for Campylobacter bacteraemia in our cohort was immunosuppression. Prognosis was generally favourable regardless of appropriateness of antibiotic therapy.

  17. Paranasal sinuses malignancies: A 12-year review of clinical characteristics

    Science.gov (United States)

    Sarafraz, Alireza; Chamani, Mojtaba; Derakhshandeh, Hossein

    2016-01-01

    Background Inadequate epidemiologic investigations of the paranasal sinuses malignancies prompted this retrospective study with special emphasis on a major group of 111 tumors. Material and Methods Clinical records of 111 patients with histologically confirmed malignant tumors of the paranasal sinuses were investigated retrospectively from April 2000 to January 2012. Collection of data included demographic information, clinical manifestations, treatment plans, and histopathology of the tumor. Results There were 69 (62.16%) male and 42 (37.83%) female patients (male-to-female ratio of 1.6:1), with a median age of 49±12.2 years (range 21 to 88 years). A high level of occurrence was noticed in the fifth (26.3%) decade of life. The most frequent histological types were squamous cell carcinoma (43.5%) and adenoid cystic carcinoma (19%). Among clinical manifestations, nasal obstruction was the most frequent followed by diplopia, and facial swelling. Fifty three patients (47.74%) were treated with combined approach of surgery and radiation therapy. Conclusions Paranasal sinuses malignancies are rare conditions with nonspecific symptoms which make early diagnosis of the lesions more challenging. The optimal therapeutic protocol for patients suffering from these tumors is still a somewhat controversial entity and requires further studies. Key words:Paranasal sinuses, malignancy, surgery,radiotherapy. PMID:27475693

  18. 40 Years of Discovery

    Energy Technology Data Exchange (ETDEWEB)

    Weinstein, B; Heller, A

    2003-07-08

    History is most interesting when seen through the eyes of those who lived it. In this 40th anniversary retrospective of bioscience research at Lawrence Livermore National Laboratory, we've asked 19 scientists to share their personal recollections about a major accomplishment in the program's history. We have not tried to create a comprehensive or seamless story. Rather, we've attempted to capture the perspectives of key individuals, each of whom worked on a research program that met significant milestones. We have focused particularly on programs and accomplishments that have shaped the current Biology and Biotechnology Research Program (BBRP). In addition, we have included a timeline of biosciences at LLNL, a history of the directorate that appeared in the Laboratory's magazine, ''Science & Technology Review'', in 2002, and a list of bioscience-related articles that have appeared over the years in ''Science & Technology Review and its predecessor, Energy & Technology Review''. The landscape of biological science today is stunningly different from 40 years ago. When LLNL bioscience began in 1963, we knew about the structure of DNA and that it was the carrier of genetic information. However, it would be another year before scientists would understand how DNA codes for the production of proteins and more than a decade before the earliest DNA sequence would be known. It is sometimes difficult to remember that it was only 15 years ago that the polymerase chain reaction, a synthetic method to amplify pieces of DNA was developed, and that only within the last half-dozen years has sequence data for entire organisms begun to be available. In this publication, we have tried to capture some of the landmark and seminal research history: radiation effects studies, which were a major reason for founding the biological research program, and flow sorting and chromosome painting, which dramatically changed our ability to

  19. 500 years after Columbus.

    Science.gov (United States)

    Imbach, A

    1992-01-01

    The astonishing range of plants and animals of Central America's 7 countries (Guatemala, Belize, Honduras, El Salvador, Nicaragua, Costa Rica and Panama) is disappearing, as 60% of its forests have been cut for lumber and firewood as well as for cotton, cattle, or subsistence crops. Up to 5 million Mayans lived sustainably for thousands of years in an area now being destroyed by a few hundred thousand inhabitants. The Spanish colonization that started 500 years ago was concentrated in Panama, Nicaragua, and Guatemala. The majority of the English-speaking country of Belize are descended from the black slave population whose culture spread down the coast to Central America. Panama's service economy is based on the Panama Canal and trade and finance. Costa Rica benefits from a tourist industry based on its natural beauty, however, it also has the highest rate of deforestation and its fast population growth could jeopardize earlier social and economic progress. In El Salvador and Guatemala long periods of civil conflict have taken their toll on the economy and the environment. El Salvador has a mountainous territory and limited natural resources and industrialization, while the best land is in the hands of a few families. Honduras and Nicaragua retain the highest proportion of forest cover of the countries in the region, despite Nicaragua's years of tyranny, then revolution and the Contra war, and Honduras's own turmoils. Belize has achieved some stability, and is now strengthening its Central American links. Its coral reefs and coastal areas offer potential for sustainable development through fishing and tourism. Central American countries face the challenges of their fragile environments and major social problems.

  20. aged over 55 years

    Directory of Open Access Journals (Sweden)

    Anna Knyszyńska

    2016-06-01

    Full Text Available Background . Aging is a physiological process during which a number of adverse and irreversible organ involution changes, leading to a reduction in functional capacity of the body, both in physical and mental terms. The risk of chronic disease and depression increases with age. Objectives . Analysis of body composition and depression in people over 55 years of age with metabolic syndrome. Material and methods . The study group is 157 persons aged 55–69 years (112 women and 45 men. The authors analyzed body composition by electrical bioimpedance analyzer (Jawon IOI 353. In addition to the assessment of depression a questionnaire involving 30-point Geriatric Depression Scale was used. Results . In the study group women scored significantly lower than men on the average values of lean body mass, and an average of 7% higher than the value determining the percentage of body fat. The vast majority (70.7%; n = 111 patients showed no signs of depression. It has been shown that women with major depression had significantly higher mean values of body fat compared to women characterized by the absence or a mild depression. Conclusions . Diagnosis of depression in the elderly may be difficult due to the presence of the “masked depression”. There is a trend indicating the relationship between the prevalence of depressive symptoms and weight and body composition of people over 55 years of age, but in order to verify it the authors need to continue the study on increased number of research groups, perhaps taking into account different environmental factors.