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Sample records for fichtel neil gehrels

  1. Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition

    International Nuclear Information System (INIS)

    Broderick, Peter; Bagratuni, Tina; Vijayakrishnan, Jairam; Lubbe, Steven; Chandler, Ian; Houlston, Richard S

    2006-01-01

    The observation that germline mutations in the oxidative DNA damage repair gene MUTYH cause colorectal cancer (CRC) provides strong evidence that dysregulation of the base excision repair (BER) pathway influences disease susceptibility. It is conceivable that germline sequence variation in other BER pathway genes such as NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 also contribute to CRC susceptibility. To evaluate whether sequence variants of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes might act as CRC susceptibility alleles, we screened the coding sequence and intron-exon boundaries of these genes in 94 familial CRC cases in which involvement of known genes had been excluded. Three novel missense variants were identified NEIL2 C367A, TDG3 A196G and UNG2 C262T in patients, which were not observed in 188 healthy control DNAs. We detected novel germline alterations in NEIL2, TDG and UNG patients with CRC. The results suggest a limited role for NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 in development of CRC

  2. Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition

    Energy Technology Data Exchange (ETDEWEB)

    Broderick, Peter; Bagratuni, Tina; Vijayakrishnan, Jairam; Lubbe, Steven; Chandler, Ian; Houlston, Richard S [Section of Cancer Genetics, Brookes Lawley Building, Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG (United Kingdom)

    2006-10-09

    The observation that germline mutations in the oxidative DNA damage repair gene MUTYH cause colorectal cancer (CRC) provides strong evidence that dysregulation of the base excision repair (BER) pathway influences disease susceptibility. It is conceivable that germline sequence variation in other BER pathway genes such as NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 also contribute to CRC susceptibility. To evaluate whether sequence variants of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes might act as CRC susceptibility alleles, we screened the coding sequence and intron-exon boundaries of these genes in 94 familial CRC cases in which involvement of known genes had been excluded. Three novel missense variants were identified NEIL2 C367A, TDG3 A196G and UNG2 C262T in patients, which were not observed in 188 healthy control DNAs. We detected novel germline alterations in NEIL2, TDG and UNG patients with CRC. The results suggest a limited role for NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 in development of CRC.

  3. X-ray and UV observations of Nova Mus 2018 with Swift

    Science.gov (United States)

    Nelson, Thomas; Mukai, Koji; Chomiuk, Laura; Li, Kwan-Kok; Kawash, Adam; Sokoloski, J. L.; Rupen, Michael; Linford, Justin; Mioduszewski, Amy

    2018-01-01

    We observed Nova Mus 2018 (PNV J11261220-6531086) with the Neil Gehrels Swift Observatory on 2018 January 21, 18 days after the initial rapid rise to V=8.8 on 2018 January 3.24 (see link below for more details).

  4. Neil Young - også kendt som Bernard Shakey

    DEFF Research Database (Denmark)

    Pedersen, Peter Ole

    2016-01-01

    A chronological analysis of the films made by the musician Neil Young. The article takes a closer look at the criticism of society and the portrayal of America and it's music culture in the works of Bernard Shakey a.k.a. Neil Young......A chronological analysis of the films made by the musician Neil Young. The article takes a closer look at the criticism of society and the portrayal of America and it's music culture in the works of Bernard Shakey a.k.a. Neil Young...

  5. Recurrent nova M31N 2008-12a: The 2017-eruption X-ray turn-off seen by Swift/XRT

    Science.gov (United States)

    Henze, M.; Darnley, M. J.; Shafter, A. W.; Kafka, S.; Kato, M.; Williams, S. C.; et al.

    2018-01-01

    The detection of supersoft X-ray source (SSS) emission from the 2017 eruption (ATel #11116) of the rapidly recurring nova M31N 2008-12a (Henze et al. 2014, 2015a, 2015b; Darnley et al. 2014, 2015, 2016) with the Neil Gehrels Swift observatory was announced in ATel #11130.

  6. What motion is: William Neile and the laws of motion.

    Science.gov (United States)

    Kemeny, Max

    2017-07-01

    In 1668-1669 William Neile and John Wallis engaged in a protracted correspondence regarding the nature of motion. Neile was unhappy with the laws of motion that had been established by the Royal Society in three papers published in 1668, deeming them not explanations of motion at all, but mere descriptions. Neile insisted that science could not be informative without a discussion of causes, meaning that Wallis's purely kinematic account of collision could not be complete. Wallis, however, did not consider Neile's objections to his work to be serious. Rather than engage in a discussion of the proper place of natural philosophy in science, Wallis decided to show how Neile's preferred treatment of motion lead to absurd conclusions. This dispute is offered as a case study of dispute resolution within the early Royal Society.

  7. Hypersensitivity of mouse NEIL1-knockdown cells to hydrogen peroxide during S phase

    International Nuclear Information System (INIS)

    Yamamoto, Ryohei; Ohshiro, Yukari; Shimotani, Tatsuhiko; Yamamoto, Mizuki; Matsuyama, Satoshi; Ide, Hiroshi; Kubo, Kihei

    2014-01-01

    Oxidative base damage occurs spontaneously due to reactive oxygen species generated as byproducts of respiration and other pathological processes in mammalian cells. Many oxidized bases are mutagenic and/or toxic, and most are repaired through the base excision repair pathway. Human endonuclease VIII-like protein 1 (hNEIL1) is thought to play an important role during the S phase of the cell cycle by removing oxidized bases in DNA replication fork-like (bubble) structures, and the protein level of hNEIL1 is increased in S phase. Compared with hNEIL1, there is relatively little information on the properties of the mouse ortholog mNEIL1. Since mouse cell nuclei lack endonuclease III-like protein (NTH) activity, in contrast to human cell nuclei, mNEIL1 is a major DNA glycosylase for repair of oxidized pyrimidines in mouse nuclei. In this study, we made mNEIL1-knockdown cells using an shRNA expression vector and examined the cell cycle-related variation in hydrogen peroxide (H 2 O 2 ) sensitivity. Hypersensitivity to H 2 O 2 caused by mNEIL1 knockdown was more significant in S phase than in G1 phase, suggesting that mNEIL1 has an important role during S phase, similarly to hNEIL1

  8. NEIL3 Repairs Telomere Damage during S Phase to Secure Chromosome Segregation at Mitosis

    Directory of Open Access Journals (Sweden)

    Jia Zhou

    2017-08-01

    Full Text Available Oxidative damage to telomere DNA compromises telomere integrity. We recently reported that the DNA glycosylase NEIL3 preferentially repairs oxidative lesions in telomere sequences in vitro. Here, we show that loss of NEIL3 causes anaphase DNA bridging because of telomere dysfunction. NEIL3 expression increases during S phase and reaches maximal levels in late S/G2. NEIL3 co-localizes with TRF2 and associates with telomeres during S phase, and this association increases upon oxidative stress. Mechanistic studies reveal that NEIL3 binds to single-stranded DNA via its intrinsically disordered C terminus in a telomere-sequence-independent manner. Moreover, NEIL3 is recruited to telomeres through its interaction with TRF1, and this interaction enhances the enzymatic activity of purified NEIL3. Finally, we show that NEIL3 interacts with AP Endonuclease 1 (APE1 and the long-patch base excision repair proteins PCNA and FEN1. Taken together, we propose that NEIL3 protects genome stability through targeted repair of oxidative damage in telomeres during S/G2 phase.

  9. Majandus soosib PPP projekte / Neil Tindal

    Index Scriptorium Estoniae

    Tindal, Neil

    2009-01-01

    Neil Tindal, kes on Suurbritannia nõustaja infrastruktuuri projektide ja avalike riigihangete alal, vastab küsimustele, mis puudutavad finantskriisi mõju Euroopa kiirrongide PPP projektide realiseerimisele ning riikliku investeerimise suurenemist PPP projektidesse

  10. Apollo 11 astronaut Neil Armstrong suits up before launch

    Science.gov (United States)

    1969-01-01

    Apollo 11 Commander Neil Armstrong prepares to put on his helmet with the assistance of a spacesuit technician during suiting operations in the Manned Spacecraft Operations Building (MSOB) prior to the astronauts' departure to Launch Pad 39A. The three astronauts, Edwin E. Aldrin Jr., Neil A Armstrong and Michael Collins, will then board the Saturn V launch vehicle, scheduled for a 9:32 a.m. EDT liftoff, for the first manned lunar landing mission.

  11. Apollo 11 astronaut Neil Armstrong looks over flight plans

    Science.gov (United States)

    1969-01-01

    Apollo 11 Commander Neil Armstrong is looking over flight plans while being assisted by a spacesuit technician during suiting operations in the Manned Spacecraft Operations Building (MSOB) prior to the astronauts' departure to Launch Pad 39A. The three astronauts, Edwin E. Aldrin Jr., Neil A. Armstrong and Michael Collins will then board the Saturn V launch vehicle, scheduled for a 9:32 a.m. EDT liftoff, for the first manned lunar landing mission.

  12. How Viral Poems are Annotated : On ‘OCD’ by Neil Hilborn

    NARCIS (Netherlands)

    van der Starre, K.A.

    2015-01-01

    In How Viral Poems are Annotated: On ‘OCD’ by Neil Hilborn Kila van der Starre explores how, where and by whom viral poems are annotated. The article focuses on the performance of the poem ‘OCD’ by Neil Hilborn that went viral in the summer of 2013 and has been viewed more than 10 million times on

  13. Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase

    Energy Technology Data Exchange (ETDEWEB)

    Prakash, Aishwarya; Moharana, Kedar; Wallace, Susan S.; Doublié, Sylvie

    2016-12-19

    The base excision repair (BER) pathway repairs oxidized lesions in the DNA that result from reactive oxygen species generated in cells. If left unrepaired, these damaged DNA bases can disrupt cellular processes such as replication. NEIL1 is one of the 11 human DNA glycosylases that catalyze the first step of the BER pathway, i.e. recognition and excision of DNA lesions. NEIL1 interacts with essential replication proteins such as the ring-shaped homotrimeric proliferating cellular nuclear antigen (PCNA). We isolated a complex formed between NEIL1 and PCNA (±DNA) using size exclusion chromatography (SEC). This interaction was confirmed using native gel electrophoresis and mass spectrometry. Stokes radii measured by SEC hinted that PCNA in complex with NEIL1 (±DNA) was no longer a trimer. Height measurements and images obtained by atomic force microscopy also demonstrated the dissociation of the PCNA homotrimer in the presence of NEIL1 and DNA, while small-angle X-ray scattering analysis confirmed the NEIL1 mediated PCNA trimer dissociation and formation of a 1:1:1 NEIL1-DNA-PCNA(monomer) complex. Furthermore, ab initio shape reconstruction provides insights into the solution structure of this previously unreported complex. Together, these data point to a potential mechanistic switch between replication and BER.

  14. Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice

    DEFF Research Database (Denmark)

    Skarpengland, Tonje; Holm, Sverre; Scheffler, Katja

    2016-01-01

    Increasing evidence suggests that oxidative DNA damage accumulates in atherosclerosis. Recently, we showed that a genetic variant in the human DNA repair enzyme NEIL3 was associated with increased risk of myocardial infarction. Here, we explored the role of Neil3/NEIL3 in atherogenesis by both...

  15. Astronaut Neil Armstrong participates in simulation training

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, Apollo 11 commander, participates in simulation training in preparation for the scheduled lunar landing mission. He is in the Apollo Lunar Module Mission SImulator in the Kennedy Space Center's Flight Crew Training Building.

  16. Acquisition of wood fuel at the Joseph C. McNeil Generating Station

    Energy Technology Data Exchange (ETDEWEB)

    Kropelin, W. [Burlington Electric Dept., VT (United States)

    1993-12-31

    The Joseph C. McNeil Generating Station is the world`s largest single boiler, municipally-owned, wood-fired electrical generating plant. The 50 megawatt McNeil Station is located in Burlington, Vermont and is owned by several Vermont public and private electric utilities. The operator and majority owner is the City of Burlington Electric Department (BED). Wood fuel procurement for the McNeil Station has been conducted in an environmentally sensitive way. Harvesting is carried out in conformance with a comprehensive wood chip harvesting policy and monitored by professional foresters. Unpredictable levels of Station operation require rigid adherence to a wood storage plan that minimizes the risk of over heating and spontaneous combustion of stockpiled fuel.

  17. APOLLO 11 COMMANDER NEIL ARMSTRONG IN SIMULATOR

    Science.gov (United States)

    1969-01-01

    Apollo 11 commander Neil Armstrong is going through flight training in the lunar module simulator situated in the flight crew training building at KSC. Armstrong will pilot the lunar module to a moon landing on July 20, following launch from KSC on July 16.

  18. Neil Armstrong chats with attendees at Apollo 11 anniversary banquet.

    Science.gov (United States)

    1999-01-01

    Former Apollo 11 astronaut Neil A. Armstrong is the center of attention at the anniversary banquet honoring the Apollo team, the people who made the entire lunar landing program possible. The banquet was held in the Apollo/Saturn V Center, part of the KSC Visitor Complex. This is the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969. Neil Armstrong was the first man to set foot on the moon. He appeared at the banquet with other former astronauts Edwin 'Buzz' Aldrin, Gene Cernan, Walt Cunningham and others.

  19. Astronaut Neil Armstrong during thermovacuum training

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, commander of the Apollo 11 lunar landing mission, is photographed during thermovacuum training in Chamber B of the Space Environment Simulation Laboratory, Building 32, Manned Spacecraft Center. He is wearing an Extravehicular Mobility Unit. The training simulated lunar surface vacuum and thermal conditions during astronaut operations outside the Lunar Module on the moon's surface. The mirror was used to reflect solar light.

  20. Astronaut Neil A. Armstrong during water egress training

    Science.gov (United States)

    1965-01-01

    Astronaut Neil A. Armstrong, Gemini 5 backup crew command pilot, sits in the Gemini Static Article 5 spacecraft and prepares to be lowered from the deck of the NASA Motor Vessel Retriever for water egress training in the Gulf.

  1. Interactions between brown bears and chum salmon at McNeil River, Alaska

    Science.gov (United States)

    Peirce, Joshua M.; Otis, Edward O.; Wipfli, Mark S.; Follmann, Erich H.

    2013-01-01

    Predation on returning runs of adult salmon (Oncorhynchus spp.) can have a large influence on their spawning success. At McNeil River State Game Sanctuary (MRSGS), Alaska, brown bears (Ursus arctos) congregate in high numbers annually along the lower McNeil River to prey upon returning adult chum salmon (O. keta). Low chum salmon escapements into McNeil River since the late 1990s have been proposed as a potential factor contributing to concurrent declines in bear numbers. The objective of this study was to determine the extent of bear predation on chum salmon in McNeil River, especially on pre-spawning fish, and use those data to adjust the escapement goal for the river. In 2005 and 2006, 105 chum salmon were radiotagged at the river mouth and tracked to determine cause and location of death. Below the falls, predators consumed 99% of tagged fish, killing 59% of them before they spawned. Subsequently, the escapement goal was nearly doubled to account for this pre-spawning mortality and to ensure enough salmon to sustain both predators and prey. This approach to integrated fish and wildlife management at MRSGS can serve as a model for other systems where current salmon escapement goals may not account for pre-spawning mortality.

  2. The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions.

    Science.gov (United States)

    Hegde, Muralidhar L; Tsutakawa, Susan E; Hegde, Pavana M; Holthauzen, Luis Marcelo F; Li, Jing; Oezguen, Numan; Hilser, Vincent J; Tainer, John A; Mitra, Sankar

    2013-07-10

    NEIL1 [Nei (endonuclease VIII)-like protein 1], one of the five mammalian DNA glycosylases that excise oxidized DNA base lesions in the human genome to initiate base excision repair, contains an intrinsically disordered C-terminal domain (CTD; ~100 residues), not conserved in its Escherichia coli prototype Nei. Although dispensable for NEIL1's lesion excision and AP lyase activities, this segment is required for efficient in vivo enzymatic activity and may provide an interaction interface for many of NEIL1's interactions with other base excision repair proteins. Here, we show that the CTD interacts with the folded domain in native NEIL1 containing 389 residues. The CTD is poised for local folding in an ordered structure that is induced in the purified fragment by osmolytes. Furthermore, deletion of the disordered tail lacking both Tyr and Trp residues causes a red shift in NEIL1's intrinsic Trp-specific fluorescence, indicating a more solvent-exposed environment for the Trp residues in the truncated protein, which also exhibits reduced stability compared to the native enzyme. These observations are consistent with stabilization of the native NEIL1 structure via intramolecular, mostly electrostatic, interactions that were disrupted by mutating a positively charged (Lys-rich) cluster of residues (amino acids 355-360) near the C-terminus. Small-angle X-ray scattering (SAXS) analysis confirms the flexibility and dynamic nature of NEIL1's CTD, a feature that may be critical to providing specificity for NEIL1's multiple, functional interactions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Neil Armstrong gets round of applaus at Apollo 11 anniversary banquet.

    Science.gov (United States)

    1999-01-01

    Former Apollo 11 astronaut Neil A. Armstrong stands to a round of applause after being introduced at the anniversary banquet honoring the Apollo team, the people who made the entire lunar landing program possible. The banquet was held in the Apollo/Saturn V Center, part of the KSC Visitor Complex. This is the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969. Neil Armstrong was the first man to set foot on the moon. He appeared at the banquet with other former astronauts Edwin 'Buzz' Aldrin, Gene Cernan, Walt Cunningham and others.

  4. Radiotelemetry to estimate stream life of adult chum salmon in the McNeil River, Alaska

    Science.gov (United States)

    Peirce, Joshua M.; Otis, Edward O.; Wipfli, Mark S.; Follmann, Erich H.

    2011-01-01

    Estimating salmon escapement is one of the fundamental steps in managing salmon populations. The area-under-the-curve (AUC) method is commonly used to convert periodic aerial survey counts into annual salmon escapement indices. The AUC requires obtaining accurate estimates of stream life (SL) for target species. Traditional methods for estimating SL (e.g., mark–recapture) are not feasible for many populations. Our objective in this study was to determine the average SL of chum salmon Oncorhynchus keta in the McNeil River, Alaska, through radiotelemetry. During the 2005 and 2006 runs, 155 chum salmon were fitted with mortality-indicating radio tags as they entered the McNeil River and tracked until they died. A combination of remote data loggers, aerial surveys, and foot surveys were used to determine the location of fish and provide an estimate of time of death. Higher predation resulted in tagged fish below McNeil Falls having a significantly shorter SL (12.6 d) than those above (21.9 d). The streamwide average SL (13.8 d) for chum salmon at the McNeil River was lower than the regionwide value (17.5 d) previously used to generate AUC indices of chum salmon escapement for the McNeil River. We conclude that radiotelemetry is an effective tool for estimating SL in rivers not well suited to other methods.

  5. Astronaut Neil Armstrong participates in simulation of moon's surface

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, wearing an Extravehicular Mobility Unit, deploys a lunar surface television camera during lunar surface simulation training in bldg 9, Manned Spacecraft Center. Armstrong is the prime crew commander of the Apollo 11 lunar landing mission.

  6. RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures.

    Science.gov (United States)

    Theriot, Corey A; Hegde, Muralidhar L; Hazra, Tapas K; Mitra, Sankar

    2010-06-04

    The human DNA glycosylase NEIL1, activated during the S-phase, has been shown to excise oxidized base lesions in single-strand DNA substrates. Furthermore, our previous work demonstrating functional interaction of NEIL1 with PCNA and flap endonuclease 1 (FEN1) suggested its involvement in replication-associated repair. Here we show interaction of NEIL1 with replication protein A (RPA), the heterotrimeric single-strand DNA binding protein that is essential for replication and other DNA transactions. The NEIL1 immunocomplex isolated from human cells contains RPA, and its abundance in the complex increases after exposure to oxidative stress. NEIL1 directly interacts with the large subunit of RPA (K(d) approximately 20 nM) via the common interacting interface (residues 312-349) in NEIL1's disordered C-terminal region. RPA inhibits the base excision activity of both wild-type NEIL1 (389 residues) and its C-terminal deletion CDelta78 mutant (lacking the interaction domain) for repairing 5-hydroxyuracil (5-OHU) in a primer-template structure mimicking the DNA replication fork. This inhibition is reduced when the damage is located near the primer-template junction. Contrarily, RPA moderately stimulates wild-type NEIL1 but not the CDelta78 mutant when 5-OHU is located within the duplex region. While NEIL1 is inhibited by both RPA and Escherichia coli single-strand DNA binding protein, only inhibition by RPA is relieved by PCNA. These results showing modulation of NEIL1's activity on single-stranded DNA substrate by RPA and PCNA support NEIL1's involvement in repairing the replicating genome. Copyright 2010 Elsevier B.V. All rights reserved.

  7. Astronaut Neil Armstrong studies rock samples during geological field trip

    Science.gov (United States)

    1969-01-01

    Astronaut Neil Armstrong, commander of the Apollo 11 lunar landing mission, studies rock samples during a geological field trip to the Quitman Mountains area near the Fort Quitman ruins in far west Texas.

  8. X-Ray Outburst from Young Star in McNeil's Nebula

    Science.gov (United States)

    2004-07-01

    Observations with NASA's Chandra X-ray Observatory captured an X-ray outburst from a young star, revealing a probable scenario for the intermittent brightening of the recently discovered McNeil's Nebula. It appears the interaction between the young star's magnetic field and an orbiting disk of gas can cause dramatic, episodic increases in the light from the star and disk, illuminating the surrounding gas. "The story of McNeil's Nebula is a wonderful example of the importance of serendipity in science," said Joel Kastner of the Rochester Institute of Technology in Rochester, New York, lead author of a paper in the July 22 issue of Nature describing the X-ray results. "Visible-light images were made of this region several months before Jay McNeil made his discovery, so it could be determined approximately when and by how much the star flared up to produce McNeil's Nebula." The small nebula, which lies in the constellation Orion about 1300 light years from Earth, was discovered with a 3-inch telescope by McNeil, an amateur astronomer from Paducah, Kentucky, in January 2004. In November 2002, a team led by Ted Simon of the Institute for Astronomy in Hawaii had observed the star-rich region with Chandra in search of young, X-ray emitting stars, and had detected several objects. Optical and infrared astronomers had, as part of independent surveys, also observed the region about a year later, in 2003. After the announcement of McNeil's discovery, optical, infrared and X-ray astronomers rushed to observe the region again. They found that a young star buried in the nebula had flared up, and was illuminating the nebula. This star was coincident with one of the X-ray sources discovered earlier by Simon. Chandra observations obtained by Kastner's group just after the optical outburst showed that the source had brightened fifty-fold in X-rays when compared to Simon's earlier observation. The visible-light eruption provides evidence that the cause of the X-ray outburst is the

  9. Astronaut Neil Armstrong participates in lunar surface siumlation training

    Science.gov (United States)

    1969-01-01

    Suited Astronaut Neil A. Armstrong, wearing an Extravehicular Mobility Unit, participates in lunar surface simulation training on April 18, 1969, in bldg 9, Manned Spacecraft Center (MSC). Armstrong is the prime crew commander of the Apollo 11 lunar landing mission. Here, he simulates scooping up a lunar surface sample.

  10. Astronaut Neil Armstrong participates in lunar surface simulation training

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, wearing an Extravehicular Mobility Unit (EMU), participates in lunar surface simulation training on April 18, 1969 in bldg 9, Manned Spacecraft Center. Armstrong is the prime crew commander of the Apollo 11 lunar landing mission. Here, he is standing on Lunar Module mockup foot pad preparing to ascend steps.

  11. Astronaut Neil Armstrong in Launch Complex 16 trailer during suiting up

    Science.gov (United States)

    1966-01-01

    Astronaut Neil A. Armstrong, command pilot of the Gemini 8 space flight, sits in the Launch Complex 16 trailer during suiting up operations for the Gemini 8 mission. Suit technician Jim Garrepy assists.

  12. Lunar Landing Training vehicle piloted by Neil Armstrong during training

    Science.gov (United States)

    1969-01-01

    A Lunar Landing Training Vehicle, piloted by Astronaut Neil Armstrong, goes through a checkout flight at Ellington Air Force Base on June 16, 1969. The total duration of the lunar simulation flight was five minutes and 59 seconds. Maximum altitude attained was about 300 feet.

  13. Toxoplasmosis a re-emerging ancient disease | Neils | Zoologist (The)

    African Journals Online (AJOL)

    Toxoplasmosis a re-emerging ancient disease. JS Neils, IA Lawal. Abstract. No Abstract. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/tzool.v4i1.45219 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  14. The DNA glycosylases OGG1 and NEIL3 influence differentiation potential, proliferation, and senescence-associated signs in neural stem cells

    International Nuclear Information System (INIS)

    Reis, Amilcar; Hermanson, Ola

    2012-01-01

    Highlights: ► DNA glycosylases OGG1 and NEIL3 are required for neural stem cell state. ► No effect on cell viability by OGG1 or NEIL3 knockdown in neural stem cells. ► OGG1 or NEIL3 RNA knockdown result in decreased proliferation and differentiation. ► Increased HP1γ immunoreactivity after NEIL3 knockdown suggests premature senescence. -- Abstract: Embryonic neural stem cells (NSCs) exhibit self-renewal and multipotency as intrinsic characteristics that are key parameters for proper brain development. When cells are challenged by oxidative stress agents the resulting DNA lesions are repaired by DNA glycosylases through the base excision repair (BER) pathway as a means to maintain the fidelity of the genome, and thus, proper cellular characteristics. The functional roles for DNA glycosylases in NSCs have however remained largely unexplored. Here we demonstrate that RNA knockdown of the DNA glycosylases OGG1 and NEIL3 decreased NSC differentiation ability and resulted in decreased expression of both neuronal and astrocytic genes after mitogen withdrawal, as well as the stem cell marker Musashi-1. Furthermore, while cell survival remained unaffected, NEIL3 deficient cells displayed decreased cell proliferation rates along with an increase in HP1γ immunoreactivity, a sign of premature senescence. Our results suggest that DNA glycosylases play multiple roles in governing essential neural stem cell characteristics.

  15. Portrait of Astronaut Neil A. Armstrong, commander of Apollo 11 mission

    Science.gov (United States)

    1969-01-01

    Portrait of Astronaut Neil A. Armstrong, commander of the Apollo 11 Lunar Landing mission in his space suit, with his helmet on the table in front of him. Behind him is a large photograph of the lunar surface.

  16. Apollo 11 Astronaut Neil Armstrong Performs Ladder Practice

    Science.gov (United States)

    1969-01-01

    In preparation of the nation's first Lunar landing mission, Apollo 11 crew members underwent training activities to practice activities they would be performing during the mission. In this photograph, Neil Armstrong, donned in his space suit, practices getting back to the first rung of the ladder on the Lunar Module (LM). The Apollo 11 mission launched from the Kennedy Space Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  17. Apollo 11 Astronaut Neil Armstrong Approaches Practice Helicopter

    Science.gov (United States)

    1969-01-01

    In preparation of the nation's first lunar landing mission, Apollo 11, crew members underwent training to practice activities they would be performing during the mission. In this photograph Neil Armstrong approaches the helicopter he flew to practice landing the Lunar Module (LM) on the Moon. The Apollo 11 mission launched from the Kennedy Space Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished

  18. The DNA glycosylases OGG1 and NEIL3 influence differentiation potential, proliferation, and senescence-associated signs in neural stem cells

    Energy Technology Data Exchange (ETDEWEB)

    Reis, Amilcar [Linnaeus Center in Developmental Biology for Regenerative Medicine (DBRM), Department of Neuroscience, Karolinska Institutet, SE 17177 Stockholm (Sweden); Hermanson, Ola, E-mail: ola.hermanson@ki.se [Linnaeus Center in Developmental Biology for Regenerative Medicine (DBRM), Department of Neuroscience, Karolinska Institutet, SE 17177 Stockholm (Sweden)

    2012-07-13

    Highlights: Black-Right-Pointing-Pointer DNA glycosylases OGG1 and NEIL3 are required for neural stem cell state. Black-Right-Pointing-Pointer No effect on cell viability by OGG1 or NEIL3 knockdown in neural stem cells. Black-Right-Pointing-Pointer OGG1 or NEIL3 RNA knockdown result in decreased proliferation and differentiation. Black-Right-Pointing-Pointer Increased HP1{gamma} immunoreactivity after NEIL3 knockdown suggests premature senescence. -- Abstract: Embryonic neural stem cells (NSCs) exhibit self-renewal and multipotency as intrinsic characteristics that are key parameters for proper brain development. When cells are challenged by oxidative stress agents the resulting DNA lesions are repaired by DNA glycosylases through the base excision repair (BER) pathway as a means to maintain the fidelity of the genome, and thus, proper cellular characteristics. The functional roles for DNA glycosylases in NSCs have however remained largely unexplored. Here we demonstrate that RNA knockdown of the DNA glycosylases OGG1 and NEIL3 decreased NSC differentiation ability and resulted in decreased expression of both neuronal and astrocytic genes after mitogen withdrawal, as well as the stem cell marker Musashi-1. Furthermore, while cell survival remained unaffected, NEIL3 deficient cells displayed decreased cell proliferation rates along with an increase in HP1{gamma} immunoreactivity, a sign of premature senescence. Our results suggest that DNA glycosylases play multiple roles in governing essential neural stem cell characteristics.

  19. Reporters Interview Family of Apollo 11 Astronaut Neil Armstrong

    Science.gov (United States)

    1969-01-01

    Newsmen talked with the wife and sons of Apollo 11 astronaut Neil A. Armstrong after the successful launch of Apollo 11 on its trajectory to the moon. The Apollo 11 mission, the first lunar landing mission, launched from the Kennedy Space Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  20. NASA Administrator Dan Goldin greets Neil Armstrong at Apollo 11 anniversary banquet.

    Science.gov (United States)

    1999-01-01

    During an anniversary banquet honoring the Apollo team, the people who made the entire lunar landing program possible, former Apollo astronaut Neil A. Armstrong (left) shakes the hand of Judy Goldin (center), wife of NASA Administrator Daniel S. Goldin (right). The banquet was held in the Apollo/Saturn V Center, part of the KSC Visitor Complex. This is the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969. Among the guests at the banquet were former Apollo astronauts are Neil A. Armstrong and Edwin 'Buzz' Aldrin who flew on Apollo 11, the launch of the first moon landing; Gene Cernan, who flew on Apollo 10 and 17 and was the last man to walk on the moon; and Walt Cunningham, who flew on Apollo 7.

  1. Apollo 11 Cmdr Neil Armstrong watches STS-83 launch

    Science.gov (United States)

    1997-01-01

    Apollo 11 Commander Neil A. Armstrong and his wife, Carol, were among the many special NASA STS-83 launch guests who witnessed the liftoff of the Space Shuttle Columbia April 4 at the Banana Creek VIP Viewing Site at KSC. Columbia took off from Launch Pad 39A at 2:20:32 p.m. EST to begin the 16-day Microgravity Science Laboratory-1 (MSL-1) mission.

  2. Charles L. Brewer Award for Distinguished Teaching of Psychology: Neil Lutsky

    Science.gov (United States)

    American Psychologist, 2011

    2011-01-01

    The American Psychological Foundation (APF) Charles L. Brewer Award for Distinguished Teaching of Psychology recognizes an outstanding career contribution to the teaching of psychology. The 2011 recipient of the Distinguished Teaching Award is Neil Lutsky. Dorothy W. Cantor, president of the APF, will present the APF Distinguished Teaching Award…

  3. NEIL2 protects against oxidative DNA damage induced by sidestream smoke in human cells.

    Directory of Open Access Journals (Sweden)

    Altaf H Sarker

    Full Text Available Secondhand smoke (SHS is a confirmed lung carcinogen that introduces thousands of toxic chemicals into the lungs. SHS contains chemicals that have been implicated in causing oxidative DNA damage in the airway epithelium. Although DNA repair is considered a key defensive mechanism against various environmental attacks, such as cigarette smoking, the associations of individual repair enzymes with susceptibility to lung cancer are largely unknown. This study investigated the role of NEIL2, a DNA glycosylase excising oxidative base lesions, in human lung cells treated with sidestream smoke (SSS, the main component of SHS. To do so, we generated NEIL2 knockdown cells using siRNA-technology and exposed them to SSS-laden medium. Representative SSS chemical compounds in the medium were analyzed by mass spectrometry. An increased production of reactive oxygen species (ROS in SSS-exposed cells was detected through the fluorescent detection and the induction of HIF-1α. The long amplicon-quantitative PCR (LA-QPCR assay detected significant dose-dependent increases of oxidative DNA damage in the HPRT gene of cultured human pulmonary fibroblasts (hPF and BEAS-2B epithelial cells exposed to SSS for 24 h. These data suggest that SSS exposure increased oxidative stress, which could contribute to SSS-mediated toxicity. siRNA knockdown of NEIL2 in hPF and HEK 293 cells exposed to SSS for 24 h resulted in significantly more oxidative DNA damage in HPRT and POLB than in cells with control siRNA. Taken together, our data strongly suggest that decreased repair of oxidative DNA base lesions due to an impaired NEIL2 expression in non-smokers exposed to SSS would lead to accumulation of mutations in genomic DNA of lung cells over time, thus contributing to the onset of SSS-induced lung cancer.

  4. Neil Jordan jagab pühapäeval Viru keskuses autogramme / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2006-01-01

    10. Pimedate Ööde Filmifestivali oodatuim külaline saabub Tallinna 2. detsembril. 3. dets. Viru keskuses Rahva Raamatu kaupluses esitletakse raamatut: Jordan, Neil. Vari / tõlkinud Krista Kaer. Tallinn : Varrak, 2006

  5. Contact/Disability Performance. An Essay Constructed between Petra Kuppers and Neil Marcus

    Science.gov (United States)

    Kuppers, Petra; Marcus, Neil

    2009-01-01

    This dialogue discusses disability and performance through poetic interrogation, interspersed with segments of Neil Marcus's play "My Sexual History." The authors touch on such topics such as sexuality and representation, dance and theatre, the management of disability staring, speech difference and writing, curiosity and shrouding. (Contains 1…

  6. Magical Realism in Neil Gaiman’s Coraline

    Directory of Open Access Journals (Sweden)

    Hosseinpour Saeede

    2016-07-01

    Full Text Available Magical realism, as a narrative mode or genre in adults’ literature, has been in vogue since its revivifying with the publication of Gabriel Garcia Marquez’s One Hundred Years of Solitude (1967. However, the depiction of the genre in children’s and juvenile literature is a new trend; the presence of its elements have been traced and proved feasibly applicable in the interpretation of recent children’s fiction such as David Almond’s Skelling (1998. In this regard, the main concern of the present article is to sift the characteristic features of magical realism within Neil Gaiman’s Coraline (2002 through the application of Wendy B. Faris’s theoretical framework of the genre therewith Tzvetan Todorov’s definition of the fantastic in order to introduce the novel as an exemplar of magical realism in the domain of children’s literature.

  7. Artists concept of Apollo 11 Astronaut Neil Armstrong on the moon

    Science.gov (United States)

    1969-01-01

    A Grumman Aircraft Engineering Corporation artist's concept depicting mankind's first walk on another celestianl body. Here, Astronaut Neil Armstrong, Apollo 11 commander, is making his first step onto the surface of the moon. In the background is the Earth, some 240,000 miles away. Armstrong. They are continuing their postflight debriefings. The three astronauts will be released from quarantine on August 11, 1969. Donald K. Slayton (right), MSC Director of Flight Crew Operations; and Lloyd Reeder, training coordinator.

  8. Humour and the Unacceptable in Neil Hamburger’s Routine

    Directory of Open Access Journals (Sweden)

    Daniel Derrin

    2014-08-01

    Full Text Available This paper addresses the comic routine of Australian born U.S. comedian Gregg Turkington’s alter-ego, ‘Neil Hamburger’, from the perspective of Aristotle’s ancient conception of the risible as a species of the unacceptable, or the unseemly. In doing so, it explores two thresholds of acceptability, subjective and social, which are relevant to an understanding of Hamburger’s comic style. The paper argues that Hamburger’s style willfully violates those thresholds, risking the audience’s laughter, and yet working towards the visualization of a less normative kind of ‘unseemliness’ that underlies Hamburger’s politics: reverence for celebrity and the sacred.

  9. Project Neil Bone: a great success!

    Science.gov (United States)

    Miles, R.

    2010-08-01

    Last October, the ARPS initiated a new observing project to make photometric observations of asteroids which reach a phase angle of 0.2° or less at opposition. The stimulus for this followed the naming last year of asteroid (7102) in honour of Neil Bone, our former Meteor Section Director, who sadly died last year. It turned out that (7102) would reach opposition on January 18 this year at an unusually low phase angle - just 0.03°. This is so small an angle that if you were standing on the asteroid on this date, you would be able to see the Earth transiting across the face of the Sun! The probability that (7102) would attain such a low phase angle is about once in several hundred years. So our project was set up with a view to observing its namesake along with a selection of thirteen other asteroids, which also happened to pass through very low phase angle at their opposition during the period 2009 October-2010 March.

  10. Telecast of Astronaut Neil Armstrong descending ladder to surface of the moon

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, Apollo 11 commander, descends the ladder of the Apollo 11 Lunar Module prior to making the first step by man on the moon. This view is a black and white reproduction taken from a telecast by the Apollo 11 lunar surface camera during extravehicular activity. The black bar running through the center of the picture is an anamoly in the television ground data system at the Goldstone Tracking Station.

  11. TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation.

    Science.gov (United States)

    Müller, Udo; Bauer, Christina; Siegl, Michael; Rottach, Andrea; Leonhardt, Heinrich

    2014-07-01

    The discovery of hydroxymethyl-, formyl- and carboxylcytosine, generated through oxidation of methylcytosine by TET dioxygenases, raised the question how these modifications contribute to epigenetic regulation. As they are subjected to complex regulation in vivo, we dissected links to gene expression with in vitro modified reporter constructs. We used an Oct4 promoter-driven reporter gene and demonstrated that in vitro methylation causes gene silencing while subsequent oxidation with purified catalytic domain of TET1 leads to gene reactivation. To identify proteins involved in this pathway we screened for TET interacting factors and identified TDG, PARP1, XRCC1 and LIG3 that are involved in base-excision repair. Knockout and rescue experiments demonstrated that gene reactivation depended on the glycosylase TDG, but not MBD4, while NEIL1, 2 and 3 could partially rescue the loss of TDG. These results clearly show that oxidation of methylcytosine by TET dioxygenases and subsequent removal by TDG or NEIL glycosylases and the BER pathway results in reactivation of epigenetically silenced genes. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  12. Neil Armstrong talks of his experiences at Apollo 11 anniversary banquet

    Science.gov (United States)

    1999-01-01

    Neil Armstrong, former Apollo 11 astronaut, and first man to walk on the moon, talks about his experiences for an enthusiastic audience at the Apollo/Saturn V Center, part of the KSC Visitor Complex. The occasion was a banquet celebrating the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969. Among other guests at the banquet were astronauts Wally Schirra, Edwin 'Buzz' Aldrin and Walt Cunningham. Gene Cernan was the last man to walk on the moon.

  13. Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity

    DEFF Research Database (Denmark)

    Aamann, Maria Diget; Hvitby, Christina Poulsen; Popuri, Venkateswarlu

    2014-01-01

    Cockayne Syndrome is a segmental premature aging syndrome, which can be caused by loss of function of the CSB protein. CSB is essential for genome maintenance and has numerous interaction partners with established roles in different DNA repair pathways including transcription coupled nucleotide...... activity on a 5-hydroxyl uracil lesion in a DNA bubble structure substrate in vitro. A novel 4,6-diamino-5-formamidopyrimidine (FapyA) specific incision activity of NEIL2 was also stimulated by CSB. To further elucidate the biological role of the interaction, immunofluorescence studies were performed...

  14. Former Astronaut Neil A. Armstrong Visits MSFC

    Science.gov (United States)

    2007-01-01

    Among several other NASA dignitaries, former astronaut Neil A. Armstrong visited the Marshall Space Flight Center (MSFC) in attendance of the annual NASA Advisory Council Meeting. While here, Mr. Armstrong was gracious enough to allow the casting of his footprint. This casting will join those of other astronauts on display at the center. Armstrong was first assigned to astronaut status in 1962. He served as command pilot for the Gemini 8 mission, launched March 16, 1966, and performed the first successful docking of two vehicles in space. In 1969, Armstrong was commander of Apollo 11, the first manned lunar landing mission, and gained the distinction of being the first man to land a craft on the Moon and the first man to step on its surface. Armstrong subsequently held the position of Deputy Associate Administrator for Aeronautics, NASA Headquarters Office of Advanced Research and Technology, from 1970 to 1971. He resigned from NASA in 1971. Pictured with Armstrong is MSFC employee Daniel McFall, who assisted with the casting procedure.

  15. Official Portrait of Astronaut Neil Armstrong

    Science.gov (United States)

    1969-01-01

    Neil Armstrong, donned in his space suit, poses for his official Apollo 11 portrait. Armstrong began his flight career as a naval aviator. He flew 78 combat missions during the Korean War. Armstrong joined the NASA predecessor, NACA (National Advisory Committee for Aeronautics), as a research pilot at the Lewis Laboratory in Cleveland and later transferred to the NACA High Speed Flight Station at Edwards AFB, California. He was a project pilot on many pioneering high speed aircraft, including the 4,000 mph X-15. He has flown over 200 different models of aircraft, including jets, rockets, helicopters, and gliders. In 1962, Armstrong was transferred to astronaut status. He served as command pilot for the Gemini 8 mission, launched March 16, 1966, and performed the first successful docking of two vehicles in space. In 1969, Armstrong was commander of Apollo 11, the first manned lunar landing mission, and gained the distinction of being the first man to land a craft on the Moon and the first man to step on its surface. Armstrong subsequently held the position of Deputy Associate Administrator for Aeronautics, NASA Headquarters Office of Advanced Research and Technology, from 1970 to 1971. He resigned from NASA in 1971.

  16. Factors Affecting Career Decision-Making: Further Validation of the O'Neil Career-Sex Role Model and the Career Factor Checklist.

    Science.gov (United States)

    Meinecke, Christine; O'Neil, James M.

    Many correlates of vocational choice have been suggested by career development theorists. A career decision-making model developed by O'Neil, Meeker, and Borgers suggests six factors (individual, societal, familial, socioeconomic, situational, psychosocial-emotional) that affect both sex role socialization and career decision-making. The validity…

  17. Astronaut Neil A. Armstrong Undergoes Communications Systems Final Check

    Science.gov (United States)

    1969-01-01

    Dunned in his space suit, mission commander Neil A. Armstrong does a final check of his communications system before before the boarding of the Apollo 11 mission. Launched via a Saturn V launch vehicle, the first manned lunar mission launched from the Kennedy Space Center, Florida on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. The 3-man crew aboard the flight consisted of astronauts Armstrong; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin, Jr., Lunar Module (LM) Pilot. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. Meanwhile, astronaut Collins piloted the CM in a parking orbit around the Moon. During a 2½ hour surface exploration, the crew collected 47 pounds of lunar surface material which was returned to Earth for analysis. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  18. Artist's rendering of astronaut Neil Armstrong planting U.S. flag on Moon

    Science.gov (United States)

    1969-01-01

    Artist's Concept: Apollo 11 astronaut Neil Armstrong, after stepping onto the lunar surface, will plant the United States flag in its soil. The flag will be made of nylone, size 3- by 5 feet on a staff 8 feet long. During flight it will be stowed in two 4-foot sections strapped to the Lunar Module ladder. Armstrong's first assignment after stepping off the ladder is to pull a 'D' ring to start a television camera. The second assignment is to erect the U.S. flag. The flag will appear to be flying in a breeze. This is done with a spring-loaded wire in the nylon cloth. With everything is working normally, this will be observed on live television.

  19. Models as Weapons: Review of Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy by Cathy O’Neil (2016

    Directory of Open Access Journals (Sweden)

    Samuel Tunstall

    2018-01-01

    Full Text Available Cathy O�Neil. Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy (New York, NY: Crown 272 pp. ISBN 978-0553418811. Accessible to a wide readership, Cathy O�Neil�s Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy provides a lucid yet alarming account of the extensive reach of mathematical models in influencing all of our lives. With a particular eye towards social justice, O�Neil not only warns modelers to be cognizant of the effects of their work on real people�especially vulnerable groups who have less power to fight back�but also encourages laypersons to take initiative in learning about the myriad ways in which big data influences their lived experiences. In this review, I highlight O�Neil�s core argument and provide beginning thoughts on how the Numeracy community might take up the book moving forward.

  20. Yves Laberge on Cross the Water Blues: African American Music in Europe (Neil A. Wynn, ed.

    Directory of Open Access Journals (Sweden)

    2010-05-01

    Full Text Available Cross the Water Blues: African American Music in Europe. Edited by Neil A. Wynn. Jackson: University Press of Mississippi, "American Made Music Series", 2007.Pp. xii + 289. ISBN 9781604735468 PaperSome scholars might wonder if there is anything new to say about the history of the blues: this overlooked book will serve as a welcome answer. A collection of fifteen new essays, mostly by renowed European scholars, Cross the Water Blues: African American Music in Europe focuses on the birth, recor...

  1. Apollo 11 Astronaut Neil Armstrong During Lunar Rock Collection Training

    Science.gov (United States)

    1969-01-01

    In this photograph, Apollo 11 astronaut Neil A. Armstrong uses a geologist's hammer in selecting rock specimens during a geological field trip to the Quitman Mountains area near the Fort Quitman ruins in far west Texas. Armstrong, alongside astronaut Edwin (Buzz) Aldrin, practiced gathering rock specimens using special lunar geological tools in preparation for the first Lunar landing. Mission was accomplished in July of the same year. Aboard the Marshall Space Fight center (MSFC) developed Saturn V launch vehicle, the Apollo 11 mission launched from The Kennedy Space Center, Florida on July 16, 1969 and safely returned to Earth on July 24, 1969. The 3-man crew aboard the flight consisted of Armstrong, commander; Aldrin, Lunar Module pilot; and a third astronaut Michael Collins, Command Module pilot. Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin, while Collins remained in lunar orbit. The crew collected 47 pounds of lunar surface material which was returned to Earth for analysis. The lunar surface exploration was concluded in 2½ hours.

  2. Between Irish National Cinema and Hollywood: Neil Jordan’s Michael Collins

    Directory of Open Access Journals (Sweden)

    Raita Merivirta-Chakrabarti

    2007-03-01

    Full Text Available When Neil Jordan’s film Michael Collins was released in 1996, it was seen by some as a Hollywood epic, by others as a great national film. I would argue that Michael Collins combines these two traditions and occupies a space between Irish national cinema and Hollywood. The subject matter, the creative talent and the locations were Irish and the film was produced by using the Irish filmmaking infrastructure and the Irish government’s support mechanisms, but it was largely financed and distributed by a Hollywood studio. Also, to make it more appealing especially globally, but probably also locally (since Hollywood is now the international standard, it makes use of Hollywood conventions, making it accessible to international audiences as well. Despite the Hollywood mode, the fact remains that Michael Collins is a national film text, and Jordan does not make too many concessions to the non-Irish audiences.

  3. Research in Hospitality Management: Contact

    African Journals Online (AJOL)

    Principal Contact. Dr Sjoerd A Gehrels Editor-in-Chief Stenden Hotel Management School, Academy of International Hospitality Research, Leeuwarden, The Netherlands Email: sjoerd.gehrels@stenden.com ...

  4. Safier, Neil. La medición del nuevo mundo. La ciencia de la Ilustración y América del Sur.

    Directory of Open Access Journals (Sweden)

    Jorge Mario Aponte Motta

    2016-01-01

    Full Text Available Reseña del libro: Safier, Neil. La medición del nuevo mundo. La ciencia de la Ilustración y América del Sur. Traducido por Alberto Castillo. Madrid: Fundación Jorge Juan-Marcial Ponds ediciones de historia, 2016. ISBN 978-84-15963-75-2

  5. Untitled

    Indian Academy of Sciences (India)

    Webber (1968) do. 6.75. ACKNOWLEDGEMENT. The authors are grateful to Indian National Committee on Space. Research (INCOSPAR) and National Aeronautics and Space Administration. (NASA) of U.S.A. for providing us the emulsion Stacks and to HDr. F. B.. McDonald and C. E. Fichtel of NASA Goddard Space Fight ...

  6. The NEIL Memory Research Unit: psychosocial, biological, physiological and lifestyle factors associated with healthy ageing: study protocol.

    Science.gov (United States)

    Hannigan, Caoimhe; Coen, Robert F; Lawlor, Brian A; Robertson, Ian H; Brennan, Sabina

    2015-01-01

    Population ageing is a global phenomenon that has characterised demographic trends during the 20th and 21st century. The rapid growth in the proportion of older adults in the population, and resultant increase in the incidence of age-related cognitive decline, dementia and Alzheimer's disease, brings significant social, economic and healthcare challenges. Decline in cognitive abilities represents the most profound threat to active and healthy ageing. Current evidence suggests that a significant proportion of cases of age-related cognitive decline and dementia may be preventable through the modification of risk factors including education, depressive symptomology, physical activity, social engagement and participation in cognitively stimulating activities. The NEIL Memory Research Unit cohort study was established to investigate factors related to brain health and the maintenance of cognitive function. A cohort of 1000 normally ageing adults aged 50 years and over are being recruited to participate in comprehensive assessments at baseline, and at follow-up once every 2 years. The assessment protocol comprises a comprehensive neuropsychological battery, some basic physical measures, psychosocial scales, questionnaire measures related to a range of health, lifestyle and behavioural factors, and a measure of resting state activity using electroencephalography (EEG). The NEIL Memory Research Unit cohort study will address key questions about brain health and cognitive ageing in the population aged 50+, with a particular emphasis on the influence of potentially modifiable factors on cognitive outcomes. Analyses will be conducted with a focus on factors involved in the maintenance of cognitive function among older adults, and therefore will have the potential to contribute significant knowledge related to key questions within the field of cognitive ageing, and to inform the development of public health interventions aimed at preventing cognitive decline and promoting

  7. Who will save the tokamak - Harry Potter, Arnold Schwarzenegger, or Shaquille O'Neil?

    Science.gov (United States)

    Freidberg, J.; Mangiarotti, F.; Minervini, J.

    2014-10-01

    The tokamak is the current leading contender for a fusion power reactor. The reason for the preeminence of the tokamak is its high quality plasma physics performance relative to other concepts. Even so, it is well known that the tokamak must still overcome two basic physics challenges before becoming viable as a DEMO and ultimately a reactor: (1) the achievement of non-inductive steady state operation, and (2) the achievement of robust disruption free operation. These are in addition to the PMI problems faced by all concepts. The work presented here demonstrates by means of a simple but highly credible analytic calculation that a ``standard'' tokamak cannot lead to a reactor - it is just not possible to simultaneously satisfy all the plasma physics plus engineering constraints. Three possible solutions, some more well-known than others, to the problem are analyzed. These visual image generating solutions are defined as (1) the Harry Potter solution, (2) the Arnold Schwarzenegger solution, and (3) the Shaquille O'Neil solution. Each solution will be described both qualitatively and quantitatively at the meeting.

  8. The utilisation of the performances of Neil Diamond for improving the classroom practices of educators: an educational appreciation

    Directory of Open Access Journals (Sweden)

    Jannie Pretorius

    2013-12-01

    Full Text Available In this research the 5D-framework of Appreciative Inquiry is used to investigate the possibility of applying the attributes and artistic strategies of the pop singer Neil Diamond for the improvement of classroom practices of educationalists. During the attendance of the performances of Diamond in 2011 in South Africa the writers and five other educationalists have identified five broad qualities and practices of Diamond. These may have application value in a school or university classroom: passionate enthusiasm, purposeful dedication, communication and interaction with the audience, refusing to conform/creating variation as well as good planning. This is the first time that the 5D-cycle has been used to study the possible utilisation of a live performance of a popular artist to facilitate the professional development of educationalists.

  9. Commercial development of the Battelle/FERCO biomass gasification process - initial operation of the McNeil gasifier

    Energy Technology Data Exchange (ETDEWEB)

    Paisley, M. [Battelle, Columbus, OH (United States); Farris, G. [Future Energy Resources Company, Atlanta, GA (United States); Slack, W. [Zurn-Nepco, South Portland, Maine (United States); Irving, J. [Burlington Electric Dept., Burlington, Vermont (United States)

    1997-07-01

    Restructuring in the utility industry has increased the emphasis on renewable energy supplies. To meet this need, the U.S. Department of Energy (DOE) has focused on a number of high efficiency power generation technologies that can effectively utilize biomass. One of these promising power generation technologies is biomass gasification coupled with either a gas turbine in a combined cycle system or a fuel cell. The gasification of biomass from renewable energy crops can efficiently and economically produce a renewable source of a clean gaseous fuel, suitable for use in these high efficiency power systems, or as a substitute fuel in other combustion devices such as boilers, kilns, or other natural gas fired equipment. This paper discusses the development and first commercial-scale application at the Burlington Electric Department's McNeil Station of the Battelle/FERCO high-throughput gasification process for gas turbine based power generation system. Projected process economics for a gas turbine combined cycle plant are presented. (author)

  10. Recurrent Outbursts Revealed in 3XMM J031820.8-663034

    Science.gov (United States)

    Zhao, Hai-Hui; Weng, Shan-Shan; Wang, Jun-Xian

    2018-06-01

    3XMM J031820.8-663034, first detected by ROSAT in NGC 1313, is one of a few known transient ultraluminous X-ray sources (ULXs). In this paper, we present decades of X-ray data of this source from ROSAT, XMM-Newton, Chandra, and the Neil Gehrels Swift Observatory. We find that its X-ray emission experienced four outbursts since 1992, with a typical recurrent time ∼1800 days, an outburst duration ∼240–300 days, and a nearly constant peak X-ray luminosity ∼1.5 × 1039 erg s‑1. The upper limit of X-ray luminosity at the quiescent state is ∼5.6 × 1036 erg s‑1, and the total energy radiated during one outburst is ∼1046 erg. The spectra at the high luminosity states can be described with an absorbed disk blackbody, and the disk temperature increases with the X-ray luminosity. We compare its outburst properties with other known transient ULXs including ESO 243-49 HLX-1. As its peak luminosity only marginally puts it in the category of ULXs, we also compare it with normal transient black hole binaries. Our results suggest that the source is powered by an accreting massive stellar-mass black hole, and the outbursts are triggered by the thermal-viscous instability.

  11. Revisiting Neil Armstrongs Moon-Landing Quote: Implications for Speech Perception, Function Word Reduction, and Acoustic Ambiguity.

    Directory of Open Access Journals (Sweden)

    Melissa M Baese-Berk

    Full Text Available Neil Armstrong insisted that his quote upon landing on the moon was misheard, and that he had said one small step for a man, instead of one small step for man. What he said is unclear in part because function words like a can be reduced and spectrally indistinguishable from the preceding context. Therefore, their presence can be ambiguous, and they may disappear perceptually depending on the rate of surrounding speech. Two experiments are presented examining production and perception of reduced tokens of for and for a in spontaneous speech. Experiment 1 investigates the distributions of several acoustic features of for and for a. The results suggest that the distributions of for and for a overlap substantially, both in terms of temporal and spectral characteristics. Experiment 2 examines perception of these same tokens when the context speaking rate differs. The perceptibility of the function word a varies as a function of this context speaking rate. These results demonstrate that substantial ambiguity exists in the original quote from Armstrong, and that this ambiguity may be understood through context speaking rate.

  12. Revisiting Neil Armstrongs Moon-Landing Quote: Implications for Speech Perception, Function Word Reduction, and Acoustic Ambiguity.

    Science.gov (United States)

    Baese-Berk, Melissa M; Dilley, Laura C; Schmidt, Stephanie; Morrill, Tuuli H; Pitt, Mark A

    2016-01-01

    Neil Armstrong insisted that his quote upon landing on the moon was misheard, and that he had said one small step for a man, instead of one small step for man. What he said is unclear in part because function words like a can be reduced and spectrally indistinguishable from the preceding context. Therefore, their presence can be ambiguous, and they may disappear perceptually depending on the rate of surrounding speech. Two experiments are presented examining production and perception of reduced tokens of for and for a in spontaneous speech. Experiment 1 investigates the distributions of several acoustic features of for and for a. The results suggest that the distributions of for and for a overlap substantially, both in terms of temporal and spectral characteristics. Experiment 2 examines perception of these same tokens when the context speaking rate differs. The perceptibility of the function word a varies as a function of this context speaking rate. These results demonstrate that substantial ambiguity exists in the original quote from Armstrong, and that this ambiguity may be understood through context speaking rate.

  13. Neil Young representation of Hernán Cortés: a critical approach from the knowledge sociology to a paradigmatic case of cognitive distortion / Hernán Cortés según Neil Young: una aproximación desde la sociología del conocimiento a un caso paradigmático de distorsión cognitiva

    Directory of Open Access Journals (Sweden)

    José Luis Palacios Gómez

    2007-10-01

    Full Text Available In this article we realize a critical approach to the good savage myth as a cognitive distortion, paradigmatically represented by a Neil Young´s musical composition on Hernan Cortez figure. We use as a tool to do that criticism some relevant contributions from philosophy, social psychology and sociology of knowledge, specially that one elaborated by P.L. Berger. It’s shown myth inconsistence and their ideological supports and utilities and we conclude that one of the main functions of sociology is to unmask both descriptions and explanations of social world.

  14. Corrigendum | Gehrels | Research in Hospitality Management

    African Journals Online (AJOL)

    Li, L. (2016). Are social media applications a facilitator or barrier to learning for tourism and hospitality management students? Research in Hospitality Management, 6 (2), 195–202. https://doi.org/10.1080/22243534.2016.1253289. Acknowledgement — I thank University of Surrey, University of Derby, and Bath Spa ...

  15. Former Dryden pilot and NASA astronaut Neil Armstrong

    Science.gov (United States)

    1991-01-01

    Famed astronaut Neil A. Armstrong, the first man to set foot on the moon during the historic Apollo 11 space mission in July 1969, served for seven years as a research pilot at the NACA-NASA High-Speed Flight Station, now the Dryden Flight Research Center, at Edwards, California, before he entered the space program. Armstrong joined the National Advisory Committee for Aeronautics (NACA) at the Lewis Flight Propulsion Laboratory (later NASA's Lewis Research Center, Cleveland, Ohio, and today the Glenn Research Center) in 1955. Later that year, he transferred to the High-Speed Flight Station at Edwards as an aeronautical research scientist and then as a pilot, a position he held until becoming an astronaut in 1962. He was one of nine NASA astronauts in the second class to be chosen. As a research pilot Armstrong served as project pilot on the F-100A and F-100C aircraft, F-101, and the F-104A. He also flew the X-1B, X-5, F-105, F-106, B-47, KC-135, and Paresev. He left Dryden with a total of over 2450 flying hours. He was a member of the USAF-NASA Dyna-Soar Pilot Consultant Group before the Dyna-Soar project was cancelled, and studied X-20 Dyna-Soar approaches and abort maneuvers through use of the F-102A and F5D jet aircraft. Armstrong was actively engaged in both piloting and engineering aspects of the X-15 program from its inception. He completed the first flight in the aircraft equipped with a new flow-direction sensor (ball nose) and the initial flight in an X-15 equipped with a self-adaptive flight control system. He worked closely with designers and engineers in development of the adaptive system, and made seven flights in the rocket plane from December 1960 until July 1962. During those fights he reached a peak altitude of 207,500 feet in the X-15-3, and a speed of 3,989 mph (Mach 5.74) in the X-15-1. Armstrong has a total of 8 days and 14 hours in space, including 2 hours and 48 minutes walking on the Moon. In March 1966 he was commander of the Gemini 8

  16. An X-ray outburst from the rapidly accreting young star that illuminates McNeil's nebula.

    Science.gov (United States)

    Kastner, J H; Richmond, M; Grosso, N; Weintraub, D A; Simon, T; Frank, A; Hamaguchi, K; Ozawa, H; Henden, A

    2004-07-22

    Young, low-mass stars are luminous X-ray sources whose powerful X-ray flares may exert a profound influence over the process of planet formation. The origin of the X-ray emission is uncertain. Although many (or perhaps most) recently formed, low-mass stars emit X-rays as a consequence of solar-like coronal activity, it has also been suggested that X-ray emission may be a direct result of mass accretion onto the forming star. Here we report X-ray imaging spectroscopy observations which reveal a factor approximately 50 increase in the X-ray flux from a young star that is at present undergoing a spectacular optical/infrared outburst (this star illuminates McNeil's nebula). The outburst seems to be due to the sudden onset of a phase of rapid accretion. The coincidence of a surge in X-ray brightness with the optical/infrared eruption demonstrates that strongly enhanced high-energy emission from young stars can occur as a consequence of high accretion rates. We suggest that such accretion-enhanced X-ray emission from erupting young stars may be short-lived, because intense star-disk magnetospheric interactions are quenched rapidly by the subsequent flood of new material onto the star.

  17. Swift UVOT Grism Observations of Nearby Type Ia Supernovae - I. Observations and Data Reduction

    Science.gov (United States)

    Pan, Y.-C.; Foley, R. J.; Filippenko, A. V.; Kuin, N. P. M.

    2018-05-01

    Ultraviolet (UV) observations of Type Ia supernovae (SNe Ia) are useful tools for understanding progenitor systems and explosion physics. In particular, UV spectra of SNe Ia, which probe the outermost layers, are strongly affected by the progenitor metallicity. In this work, we present 120 Neil Gehrels Swift Observatory UV spectra of 39 nearby SNe Ia. This sample is the largest UV (λ Ia to date, doubling the number of UV spectra and tripling the number of SNe with UV spectra. The sample spans nearly the full range of SN Ia light-curve shapes (Δm15(B) ≈ 0.6-1.8 mag). The fast turnaround of Swift allows us to obtain UV spectra at very early times, with 13 out of 39 SNe having their first spectra observed ≳ 1 week before peak brightness and the earliest epoch being 16.5 days before peak brightness. The slitless design of the Swift UV grism complicates the data reduction, which requires separating SN light from underlying host-galaxy light and occasional overlapping stellar light. We present a new data-reduction procedure to mitigate these issues, producing spectra that are significantly improved over those of standard methods. For a subset of the spectra we have nearly simultaneous Hubble Space Telescope UV spectra; the Swift spectra are consistent with these comparison data.

  18. Connecting entrepreneurship and education | Gehrels | Research in ...

    African Journals Online (AJOL)

    The aim of this research is to explore the contextual characteristics of a particular group of Dutch restaurant owners, the successful culinary entrepreneurs (SCEs), to examine how these contextual characteristics might be used in a hospitality education. This very small segment of the Dutch restaurant business (0.2–0.5% of ...

  19. Editorial

    African Journals Online (AJOL)

    This edition of Research in Hospitality Management follows all the themes ... Hotel quality in the European Capital of Culture: Leeuwarden 2018 by Gehrels and ... restaurants with particular insights into the service of wines associated with ...

  20. Time domain astronomy with Swift and Fermi | Gehrels | Rwanda ...

    African Journals Online (AJOL)

    Swift and Fermi are unveiling an unexpectedly rich tapestry of behavior in the transient γ−ray sky. Sources which were already known to be transient − such as pulsars, gamma-ray bursts, and blazars − have been studied in ever-increasing detail. For example, Fermi/LAT has detected 117 pulsars of which 56 are new.

  1. Time domain astronomy with Swift and Fermi | Gehrels | Rwanda ...

    African Journals Online (AJOL)

    Rwanda Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 1, No 1 (2016) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your ...

  2. The NuSTAR view on Hard-TeV BL Lacs

    Science.gov (United States)

    Costamante, L.; Bonnoli, G.; Tavecchio, F.; Ghisellini, G.; Tagliaferri, G.; Khangulyan, D.

    2018-05-01

    Hard-TeV BL Lacs are a new type of blazars characterized by a hard intrinsic TeV spectrum, locating the peak of their gamma-ray emission in the spectral energy distribution (SED) above 2-10 TeV. Such high energies are problematic for the Compton emission, using a standard one-zone leptonic model. We study six examples of this new type of BL Lacs in the hard X-ray band with NuSTAR. Together with simultaneous observations with the Neil Gehrels Swift Observatory, we fully constrain the peak of the synchrotron emission in their SED, and test the leptonic synchrotron self-Compton (SSC) model. We confirm the extreme nature of 5 objects also in the synchrotron emission. We do not find evidence of additional emission components in the hard X-ray band. We find that a one-zone SSC model can in principle reproduce the extreme properties of both peaks in the SED, from X-ray up to TeV energies, but at the cost of i) extreme electron energies with very low radiative efficiency, ii) conditions heavily out of equipartition (by 3 to 5 orders of magnitude), and iii) not accounting for the simultaneous UV data, which then should belong to a different emission component, possibly the same as the far-IR (WISE) data. We find evidence of this separation of the UV and X-ray emission in at least two objects. In any case, the TeV electrons must not "see" the UV or lower-energy photons, even if coming from different zones/populations, or the increased radiative cooling would steepen the VHE spectrum.

  3. RHM 4.indb

    African Journals Online (AJOL)

    Jane

    Research in Hospitality Management 2014, 4(1&2): 97–104. Printed in The Netherlands ... today's society, fortunately, is no longer the sole case (McClure. 2009). ..... the concepts and theoretical themes as Gehrels found in his research into .... Small Business Service (2003), A strategic framework for women's enterprise.

  4. Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication.

    Science.gov (United States)

    Bj Rås, Karine Ø; Sousa, Mirta M L; Sharma, Animesh; Fonseca, Davi M; S Gaard, Caroline K; Bj Rås, Magnar; Otterlei, Marit

    2017-08-21

    Base lesions in DNA can stall the replication machinery or induce mutations if bypassed. Consequently, lesions must be repaired before replication or in a post-replicative process to maintain genomic stability. Base excision repair (BER) is the main pathway for repair of base lesions and is known to be associated with DNA replication, but how BER is organized during replication is unclear. Here we coupled the iPOND (isolation of proteins on nascent DNA) technique with targeted mass-spectrometry analysis, which enabled us to detect all proteins required for BER on nascent DNA and to monitor their spatiotemporal orchestration at replication forks. We demonstrate that XRCC1 and other BER/single-strand break repair (SSBR) proteins are enriched in replisomes in unstressed cells, supporting a cellular capacity of post-replicative BER/SSBR. Importantly, we identify for the first time the DNA glycosylases MYH, UNG2, MPG, NTH1, NEIL1, 2 and 3 on nascent DNA. Our findings suggest that a broad spectrum of DNA base lesions are recognized and repaired by BER in a post-replicative process. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  5. Intensity and Polarization Line Profiles in a Semi-Infinite Rayleigh ...

    Indian Academy of Sciences (India)

    tribpo

    Fymat, A. L. 1974, in Planets, Stars and Nebulae, Ed. T. Gehrels, University of Arizona Press, Tuc- son, p. 617. Lenoble, J. 1970, J. quantit. Spectrosc. radiat, Transfer, 10, 533. Molenkamp, C. R. 1972, PhD Dissertation, University of Arizona. Van de Hulst, Η. C. 1980, Multiple Light Scattering, Vol. 2, Academic Press, New ...

  6. Late Quaternary stratigraphic development in the lower Luni, Mahi ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    in the Thar desert as compared to that at the desert margin; this makes purely lithostratigraphic correlations ... Significant accumulation of continental sedimen- .... cambrian granites near Dharoi, in the foothill zone. ...... Oil. Nat. Gas Comm., Dehradun. 6(2) 37–50. DeCelles P G, Gehrels G E, Quade J and Ojha T P 1998.

  7. Author Details

    African Journals Online (AJOL)

    Gehrels, SA. Vol 1, No 1 (2011) - Articles Employer branding: A new approach for the hospitality industry. Abstract PDF. ISSN: 2224-3534. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

  8. Former Dryden pilot and NASA astronaut Neil Armstrong being inducted into the Aerospace Walk of Hono

    Science.gov (United States)

    1991-01-01

    Famed astronaut Neil A. Armstrong, the first man to set foot on the moon during the historic Apollo 11 space mission in July 1969, served for seven years as a research pilot at the NACA-NASA High-Speed Flight Station, now the Dryden Flight Research Center, at Edwards, California, before he entered the space program. Armstrong joined the National Advisory Committee for Aeronautics (NACA) at the Lewis Flight Propulsion Laboratory (later NASA's Lewis Research Center, Cleveland, Ohio, and today the Glenn Research Center) in 1955. Later that year, he transferred to the High-Speed Flight Station at Edwards as an aeronautical research scientist and then as a pilot, a position he held until becoming an astronaut in 1962. He was one of nine NASA astronauts in the second class to be chosen. As a research pilot Armstrong served as project pilot on the F-100A and F-100C aircraft, F-101, and the F-104A. He also flew the X-1B, X-5, F-105, F-106, B-47, KC-135, and Paresev. He left Dryden with a total of over 2450 flying hours. He was a member of the USAF-NASA Dyna-Soar Pilot Consultant Group before the Dyna-Soar project was cancelled, and studied X-20 Dyna-Soar approaches and abort maneuvers through use of the F-102A and F5D jet aircraft. Armstrong was actively engaged in both piloting and engineering aspects of the X-15 program from its inception. He completed the first flight in the aircraft equipped with a new flow-direction sensor (ball nose) and the initial flight in an X-15 equipped with a self-adaptive flight control system. He worked closely with designers and engineers in development of the adaptive system, and made seven flights in the rocket plane from December 1960 until July 1962. During those fights he reached a peak altitude of 207,500 feet in the X-15-3, and a speed of 3,989 mph (Mach 5.74) in the X-15-1. Armstrong has a total of 8 days and 14 hours in space, including 2 hours and 48 minutes walking on the Moon. In March 1966 he was commander of the Gemini 8

  9. Biological Investigation of the Stimulated Flapping Motions of the Moth, Manduca sexta

    Science.gov (United States)

    2011-03-01

    have gates that open and close in response to changes in the membrane potential ( Cambell Neil A, Reece, & Mitchell, 1999). To understand what...intensity of a stimulus ( Cambell Neil A, Reece, & Mitchell, 1999). This is very relevant to research conducted here because the AP threshold must be...Containing a Retrospective view of every discovery and practical improvement in the medical sciences., 428. Cambell Neil A, Reece, J. B., & Mitchell, L

  10. Tark raadio / Neil Savage

    Index Scriptorium Estoniae

    Savage, Neil

    2006-01-01

    California Santa Barbara ülikooli infotehnoloogia abiprofessor Heather Zheng tegeleb küsimusega, kuidas traadita seadmeid tõhusamalt eetrisse ära mahutada. Artikkel üldpealkirja all: 10 tulevikutehnoloogiat

  11. Contribution of tropical cyclones to the air-sea CO2 flux: A global view

    Digital Repository Service at National Institute of Oceanography (India)

    Levy, M.; Lengaigne, M.; Bopp, L.; Vincent, E.M.; Madec, G.; Ethe, C.; DileepKumar, M.; Sarma, V.V.S.S.

    .ocemod.2006.11.003.501 D’Asaro, E. (2003), The ocean boundary layer below hurricane dennis, Journal of physical502 oceanography, 33(3), 561–579.503 D’Asaro,E.,andC.McNeil(2007),Air-seagasexchangeatextremewindspeedsmeasured504 by autonomous oceanographic floats... at high wind speed [Liss and Merlivat, 1986; Wanninkhof, 1992; D’Asaro and McNeil,55 2007; McNeil and D’Asaro, 2007]. TCs also impact F CO 2 because their intense surface56 winds increase vertical entrainment of subsurface waters (hereafter referred...

  12. Irooniline pilguheit Iirima lähiajaloole / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013

    2001-01-01

    Mängufilm "Väike lihunik" ("The Butcher Boy") : Stsenaristid Neil Jordan ja Patrick McCabe viimase samanimelise romaani järgi : režissöör Neil Jordan : Ameerika Ühendriigid 1997. Ka : Teleleht nr. 1, lk. 4

  13. The ALMA early science view of FUor/EXor objects - IV. Misaligned outflows in the complex star-forming environment of V1647 Ori and McNeil's Nebula

    Science.gov (United States)

    Principe, David A.; Cieza, Lucas; Hales, Antonio; Zurlo, Alice; Williams, Jonathan; Ruíz-Rodríguez, Dary; Canovas, Hector; Casassus, Simon; Mužić, Koraljka; Perez, Sebastian; Tobin, John J.; Zhu, Zhaohuan

    2018-01-01

    We present Atacama Large Millimeter/sub-millimeter Array (ALMA) observations of the star-forming environment surrounding V1647 Ori, an outbursting FUor/EXor pre-main sequence star. Dust continuum and the (J = 2 - 1) 12CO, 13CO, C18O molecular emission lines were observed to characterize the V1647 Ori circumstellar disc and any large scale molecular features present. We detect continuum emission from the circumstellar disc and determine a radius r = 40 au, inclination i = 17°+6-9 and total disc mass of Mdisc of ∼0.1 M⊙. We do not identify any disc structures associated with nearby companions, massive planets or fragmentation. The molecular cloud environment surrounding V1647 Ori is both structured and complex. We confirm the presence of an excavated cavity north of V1647 Ori and have identified dense material at the base of the optical reflection nebula (McNeil's Nebula) that is actively shaping its surrounding environment. Two distinct outflows have been detected with dynamical ages of ∼11 700 and 17 200 yr. These outflows are misaligned suggesting disc precession over ∼5500 yr as a result of anisotropic accretion events is responsible. The collimated outflows exhibit velocities of ∼2 km s-1, similar in velocity to that of other FUor objects presented in this series, but significantly slower than previous observations and model predictions. The V1647 Ori system is seemingly connected by an 'arm' of material to a large unresolved structure located ∼20 arcsec to the west. The complex environment surrounding V1647 Ori suggests it is in the early stages of star formation, which may relate to its classification as both a FUor and EXor type object.

  14. Analysis of DNA repair gene polymorphisms and survival in low-grade and anaplastic gliomas

    DEFF Research Database (Denmark)

    Berntsson, Shala Ghaderi; Wibom, Carl; Sjöström, Sara

    2011-01-01

    different DNA repair genes (ATM, NEIL1, NEIL2, ERCC6 and RPA4) which were associated with survival. Finally, these eight genetic variants were adjusted for treatment, malignancy grade, patient age and gender, leaving one variant, rs4253079, mapped to ERCC6, with a significant association to survival (OR 0...

  15. Differential effects of silver nanoparticles on DNA damage and DNA repair gene expression in Ogg1-deficient and wild type mice.

    Science.gov (United States)

    Nallanthighal, Sameera; Chan, Cadia; Murray, Thomas M; Mosier, Aaron P; Cady, Nathaniel C; Reliene, Ramune

    2017-10-01

    Due to extensive use in consumer goods, it is important to understand the genotoxicity of silver nanoparticles (AgNPs) and identify susceptible populations. 8-Oxoguanine DNA glycosylase 1 (OGG1) excises 8-oxo-7,8-dihydro-2-deoxyguanine (8-oxoG), a pro-mutagenic lesion induced by oxidative stress. To understand whether defects in OGG1 is a possible genetic factor increasing an individual's susceptibly to AgNPs, we determined DNA damage, genome rearrangements, and expression of DNA repair genes in Ogg1-deficient and wild type mice exposed orally to 4 mg/kg of citrate-coated AgNPs over a period of 7 d. DNA damage was examined at 3 and 7 d of exposure and 7 and 14 d post-exposure. AgNPs induced 8-oxoG, double strand breaks (DSBs), chromosomal damage, and DNA deletions in both genotypes. However, 8-oxoG was induced earlier in Ogg1-deficient mice and 8-oxoG levels were higher after 7-d treatment and persisted longer after exposure termination. AgNPs downregulated DNA glycosylases Ogg1, Neil1, and Neil2 in wild type mice, but upregulated Myh, Neil1, and Neil2 glycosylases in Ogg1-deficient mice. Neil1 and Neil2 can repair 8-oxoG. Thus, AgNP-mediated downregulation of DNA glycosylases in wild type mice may contribute to genotoxicity, while upregulation thereof in Ogg1-deficient mice could serve as an adaptive response to AgNP-induced DNA damage. However, our data show that Ogg1 is indispensable for the efficient repair of AgNP-induced damage. In summary, citrate-coated AgNPs are genotoxic in both genotypes and Ogg1 deficiency exacerbates the effect. These data suggest that humans with genetic polymorphisms and mutations in OGG1 may have increased susceptibility to AgNP-mediated DNA damage.

  16. Swift: 10 Years of Discovery

    Science.gov (United States)

    2014-12-01

    association. We acknowledge valuable inputs from the conference SOC and from the Swift User Committee Chair Dieter Hartmann. We also thank the LOC for their unrelenting efforts to solve all practical details. We would like to acknowledge financial support from INAF, ASI and NASA/GSFC. Patrizia Caraveo Neil Gehrels Gianpiero Tagliaferri

  17. Inhibition of DNA glycosylases via small molecule purine analogs.

    Directory of Open Access Journals (Sweden)

    Aaron C Jacobs

    Full Text Available Following the formation of oxidatively-induced DNA damage, several DNA glycosylases are required to initiate repair of the base lesions that are formed. Recently, NEIL1 and other DNA glycosylases, including OGG1 and NTH1 were identified as potential targets in combination chemotherapeutic strategies. The potential therapeutic benefit for the inhibition of DNA glycosylases was validated by demonstrating synthetic lethality with drugs that are commonly used to limit DNA replication through dNTP pool depletion via inhibition of thymidylate synthetase and dihydrofolate reductase. Additionally, NEIL1-associated synthetic lethality has been achieved in combination with Fanconi anemia, group G. As a prelude to the development of strategies to exploit the potential benefits of DNA glycosylase inhibition, it was necessary to develop a reliable high-throughput screening protocol for this class of enzymes. Using NEIL1 as the proof-of-principle glycosylase, a fluorescence-based assay was developed that utilizes incision of site-specifically modified oligodeoxynucleotides to detect enzymatic activity. This assay was miniaturized to a 1536-well format and used to screen small molecule libraries for inhibitors of the combined glycosylase/AP lyase activities. Among the top hits of these screens were several purine analogs, whose postulated presence in the active site of NEIL1 was consistent with the paradigm of NEIL1 recognition and excision of damaged purines. Although a subset of these small molecules could inhibit other DNA glycosylases that excise oxidatively-induced DNA adducts, they could not inhibit a pyrimidine dimer-specific glycosylase.

  18. Otvetshajet : Nele Labi : rukovoditel otdela Estonskogo departamenta rõnka truda / Nele Labi

    Index Scriptorium Estoniae

    Labi, Nele

    2007-01-01

    Tööturuameti osakonnajuhataja vastab küsimustele, kas on normaalne niisugune olukord, et iga neljas tööeas inimene ei tööta ega püüagi tööd leida, milliseid teenuseid tööturuamet pakub neile, kes tahavad tööd leida ning mida teha neil, kes on kaotanud lootuse leida tööd oma vanuse või tervise tõttu

  19. The charge deposition in the numerical simulation of high-current beam

    International Nuclear Information System (INIS)

    Wang Shijun

    1987-01-01

    A new method of charge deposition of high-current beam, conservation-map method, is given. THe advantages of Neil's and other various methods are adopted. The mistake of Neil's method and the limitation of other various methods is discarded. So the method is accurate without additional assumption. The method not only applies to the case of steady laminar flow but also applies to the case of steady non-laminar flow

  20. Determine the Impact of Novel BRCA1 Translation Start Sites on Therapy Resistance in Ovarian Cancer

    Science.gov (United States)

    2017-09-01

    Award Number: W81XWH-15-1-0197 TITLE: PRINCIPAL INVESTIGATOR: Neil Johnson, Ph.D. CONTRACTING ORGANIZATION: Institute for Cancer Research...Therapy Resistance in Ovarian Cancer The views, opinions and/or findings contained in this report are those of the author(s) and should not be...Start Sites on Therapy 5b. GRANT NUMBER Resistance in Ovarian Cancer W81XWH-15-1-0197 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Neil

  1. The Right US Strategy for Iran

    Science.gov (United States)

    2007-04-01

    King , King of Kings , King of countries containing all kinds of men, King in this great earth far and wide, son of Hystaspes, an Achaemenian , a...Highlights of the Iraq Strategy Review, January 2007, http://www.whitehouse.gov/nsc/iraq/2007/iraq-strategy011007. pdf . 13 Greg Jaffe and Neil King Jr...do if Iraq Implodes?” August 2006, Brookings Report, (Washington DC) http://www.brook.edu/views/articles/pollack/20060820. pdf . 21 Neil King Jr. and

  2. Editorial: Behind the Making

    Directory of Open Access Journals (Sweden)

    Lars de Wildt

    2017-06-01

    Full Text Available Few theses, proposals and books in game studies start without some statement of the importance of video games as a media format. However, despite this emphasis on the industry’s size and importance, very little academic attention goes toward what is behind the process of designing games. Game developer Katharine Neil, writing about the state of the game industry and its relation to academia mounts a call to arms. “We can demand research and development into design support technology — not for more tools for prototyping and production or metrics, but for tools that support design thinking. For Neil, these have led to a palpable stagnation in game design. Judging by the articles selected for this issue of Press Start, young game scholars increasingly seek to ameliorate both the lacking academic reflection on game design; and the lack of communication that Neil diagnoses between academics and game makers.

  3. Browse Author Index

    African Journals Online (AJOL)

    Items 1 - 50 of 66 ... A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All. J. J. Al-Rehaily, A. J. Anderegg, Robert · J. Budenberg, William · J. Coville, Neil · J. Coville*, Neil · J. Edet, Ekanem · J. Hodgson, Derek · J. Hodgson, Derek · J. Hu, Y. J. Janusz, Stefan · J. Jones, Christopher · J. Kiplimo, Joyce · J. López-Muñoz, M.

  4. New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.

    Science.gov (United States)

    Dutta, Arijit; Yang, Chunying; Sengupta, Shiladitya; Mitra, Sankar; Hegde, Muralidhar L

    2015-05-01

    Oxidized bases in the mammalian genome, which are invariably mutagenic due to their mispairing property, are continuously induced by endogenous reactive oxygen species and more abundantly after oxidative stress. Unlike bulky base adducts induced by UV and other environmental mutagens in the genome that block replicative DNA polymerases, oxidatively damaged bases such as 5-hydroxyuracil, produced by oxidative deamination of cytosine in the template strand, do not block replicative polymerases and thus need to be repaired prior to replication to prevent mutation. Following up our earlier studies, which showed that the Nei endonuclease VIII like 1 (NEIL1) DNA glycosylase, one of the five base excision repair (BER)-initiating enzymes in mammalian cells, has enhanced expression during the S-phase and higher affinity for replication fork-mimicking single-stranded (ss) DNA substrates, we recently provided direct experimental evidence for NEIL1's role in replicating template strand repair. The key requirement for this event, which we named as the 'cow-catcher' mechanism of pre-replicative BER, is NEIL1's non-productive binding (substrate binding without product formation) to the lesion base in ss DNA template to stall DNA synthesis, causing fork regression. Repair of the lesion in reannealed duplex is then carried out by NEIL1 in association with the DNA replication proteins. NEIL1 (and other BER-initiating enzymes) also interact with several accessory and non-canonical proteins including the heterogeneous nuclear ribonucleoprotein U and Y-box-binding protein 1 as well as high mobility group box 1 protein, whose precise roles in BER are still obscure. In this review, we have discussed the recent advances in our understanding of oxidative genome damage repair pathways with particular focus on the pre-replicative template strand repair and the role of scaffold factors like X-ray repairs cross-complementing protein 1 and poly (ADP-ribose) polymerase 1 and other accessory

  5. Wallis, Neil (Energy Saving Trust, London (GB))

    Energy Technology Data Exchange (ETDEWEB)

    UK tax policies to control carbon dioxide emissions from motor vehicles - early impacts and lessons for other European countries

    2003-07-01

    Road transport emissions of carbon dioxide represent 22% of total UK emissions and are thus an important focus for policies designed to help meet the UK's climate change commitments. Vehicle CO{sub 2} emissions are determined by the carbon content of the fuel, vehicle efficiency and miles travelled. Both Europe (through the European association of car manufacturers, ACEA) and Japan have made voluntary commitments to reduce new car fuel consumption by around 25%, and the US government has announced a programme with car makers to develop new technologies to help curb carbon emissions. In Europe, the UK was the first country to introduce an explicit CO{sub 2} basis for taxation on vehicle ownership. Vehicle excise duty (VED), which is paid by car owners on an annual basis, is now graduated according to vehicles' CO{sub 2} emissions. A revised company car tax (CCT), introduced in 2002, also levies tax based on vehicles' CO{sub 2} emissions (with an adjustment for other pollutants). The introduction of this new basis for taxation, and the expectation that tax rates between low and high carbon vehicles will get steeper in the future, has led to a spate of advertising - in both the trade and consumer press - focusing on vehicles' carbon dioxide output in preference to speed, comfort or other factors. This paper is intended to describe how these new taxes work, place them within their national and European contexts and provide early evidence of any observed impacts since their introduction.

  6. Monumentalnõi obraz svobodõ / Iosef Kats

    Index Scriptorium Estoniae

    Kats, Iosef

    2007-01-01

    Tallinna Vabadussamba kavandi avalik arutelu Rahvusraamatukogus. Kavandi autorid Andri Laidre ja Rainer Sternfeld neile osaks saanud kriitikast ja vabadussamba materjalina kasutatava klaasi tugevusest

  7. Taxonomic identity and physiological ecology of Chlamydomonas hedleyi sp. nov. , algal flagellate symbiont from the foraminifer Archaias angulatus

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J J; Crockett, L J; Hagen, J; Stone, R J

    1975-12-31

    The fine structure of the symbiotic alga isolated from the foraminiferan Archaias angulatus (Fichtel et Moll) DeMontfort is typical of the Chlorophyceae of the volvocalean and chlorococcalean lines. Spherical non-motile cells, 10--14 ..mu..m in diameter, characterize the dominant life cycle phase. Long oval motile forms with truncated apices are present 3--5 days after transfer to fresh medium. The pyrenoids are embedded anteriorly in the singly bilobed chloroplast and are surrounded by a sheath of starch platelets. In spite of the non-motile state of cells in older cultures (which is perhaps a reflection of its normally symbiotic condition), the alga is identified as a species of the volvocalean genus Chlamydomonas and is named C. hedleyi sp. nov. The symbiont has no vitamin or organic requirements but growth is increased threefold in the presence of thiamine, and twofold in the presence of 1 ..mu..m glutamic acid, histidine and methionine. Urea was the best nitrogen source tested. Purines and pyrimidines did not serve as nitrogen sources. Chlamydomonas hedleyi grows well in a salinity range of 6- greater than 52 per thousand and a pH range of 6--8.5. 7.04 x 10/sup -7/ M carbon h/sup -1/ g/sup -1/ was fixed by the symbiont, 57 percent being released into the medium as a chromatographically homogeneous organic molecule provisionally identified as mannitol.

  8. Euroliidu väikeriikidel läheb suurtest paremini / Harold James

    Index Scriptorium Estoniae

    James, Harold

    2005-01-01

    Vanade Euroopa Liidu liikmesriikide hirmudest seoses Euroopa Liidu laienemisega. Ühenduse väikeriikide paindlikkus ja kohanemisvõime on taganud neile praeguses geopoliitilises ning majanduslikus keskkonnas edu

  9. Ubiitsa globalizatsii / Branko Milanovic

    Index Scriptorium Estoniae

    Milanovic, Branko

    2006-01-01

    Globaliseerumist ohustavatest teguritest. Autor leiab, et globaliseerumise jätkumiseks tuleb neil riikidel, kus on suured erinevused inimeste keskmiste sissetulekute vahel, leida võimalusi nende ühtlustamiseks

  10. Why So Many More Americans Die in Fires

    Science.gov (United States)

    Cranberg, Lawrence

    2009-03-01

    ``Why So Many More Americans Die in Fires'' is the headline on Page 3 of The New York Times' full-page story on December 22, l991, by D. G. McNeil, Jr. This is a partial report based on personal experience with domestic fire making for thermal comfort since l975 (1) and a published claim (2) of unique safety benefits.The McNeil report attributes the problem to ``A Case of Bad Attitude'' and ``A Reliance on Technology.'' That implies a ``bad attitude'' on the part of technologists - a conclusion consistent with this technologist's thirty-five years of experience with fellow technologists, who has found ``buck-passing'' the favorite recourse of technologists in the highest places in government even though, as McNeil has written, ``Many children never wake up. Smoke or toxic gases overcome them as they sleep. When fire fighters lift them, their imprints remain.'' Regrettably, in this author's experience, the courts have also displayed a ``bad attitude'' where ``life and death issues'' have been pleaded. 1. L. Cranberg, Slot Flame Stablity with Hohlraum Radiation Pattern, BAPS, Series II, Vol. 20, No. 9, Sept., l978. 2. L. Cranberg, Fireplace Firesafety, Fire Journal, Letter, May/June,l987

  11. The Estonian Foundation – What is Missing for It to Be A Well-Designed Wealth-Management Vehicle for Local and Foreign High-Net-Worth Individuals? / Katrin Sepp , Urmas Kaarlep

    Index Scriptorium Estoniae

    Sepp, Katrin

    2016-01-01

    Erahuvides sihtasutustest, neile kohalduvast seadusest Eestis ja kohalduva seaduse parendamise ettepanekutest teiste riikide näitel. Erahuvides sihtasutuste kasutamise eesmärkidest ja sellega seonduvatest probleemidest Eesti seadusandluses

  12. Saame tuttavaks Per Magnusson / Joosep Tikk

    Index Scriptorium Estoniae

    Tikk, Joosep

    2013-01-01

    Rootsi tasemel neli tärni kolmevõistluse rajameistri ning tehnilinse delegaadi koolitusest 11.-12. mail Koordi tallides eelkõige neile, kes soovivad saada tehnilisteks delegaatideks ja rajameistriks

  13. Anneliis Kõiv jälle esimees / Tõnis Tõnisson

    Index Scriptorium Estoniae

    Tõnisson, Tõnis, 1945-

    2009-01-01

    29. mail valis Eesti Kultuurkapitali Raplamaa ekspertgrupi uus koosseis oma esimeheks Anneliis Kõivu, aseesimeheks Age Rebeli. Lisaks neile kuuluvad grupi uude koosseisu Darja Lehtsalu, Andres Elmik ja Riho Pohla

  14. Pop / Tristan Priimägi

    Index Scriptorium Estoniae

    Priimägi, Tristan, 1976-

    2006-01-01

    Heliplaatidest: Ghostface Killah "Fishscale", Neil Young "Living With War", Pet Shop Boys "Fundamental", Vind Project "Vind Project", Diesler "Keepie Uppies", Akvarium "Bespetshnõi Russkii Brodjaga", Hardcore Superstar "Hardcore Superstar"

  15. Omavalitsus on riigi täisväärtuslik osa / Uno Silberg

    Index Scriptorium Estoniae

    Silberg, Uno, 1964-

    2005-01-01

    Autor on seisukohal, et valitsus peab kohalikele omavalitsustele tagama tulubaasi, mis katab neile pandud ülesannete täitmiseks vajalikud kulud ning võimaldab teha kohalikuks arenguks vajalikke investeeringuid

  16. Supermani esiisa / Laurence Lumiere

    Index Scriptorium Estoniae

    Lumiere, Laurence

    2007-01-01

    Anglosaksi eepose "Beowulf" alusel on valminud samanimeline USA seiklusfilm : stsenaristid Neil Gaiman, Roger Avary : režissöör Robert Zemeckis : osades Anthony Hopkins, Angelina Jolie, Ray Winstone

  17. Too Much Love Will Kill You / Ireene Viktor

    Index Scriptorium Estoniae

    Viktor, Ireene

    2009-01-01

    Tartu Uue Teatri lavastusest "Viimased korraldused neile, keda ma kunagi olen armastanud". Kontseptsioon, lavastus, helikujundus ja esitus Taavi Eelmaa ja Taavet Jansen. Esietendus 13. märtsil Kanuti Gildi saalis

  18. Uusi heliplaate / Tõnu Pedaru

    Index Scriptorium Estoniae

    Pedaru, Tõnu

    2000-01-01

    Uutest plaatidest Neil Young "Silver & Gold", Toni Braxton "The Heat", *N Sync "No Strings Attached", The Wannadies "Yeah", Jimmie's chicken Shack "Bring Your Own Stereo", Tõnis Mägi "Eesti kullafond"

  19. Plaadid / Mari Peegel

    Index Scriptorium Estoniae

    Peegel, Mari, 1978-

    2005-01-01

    Uutest heliplaatidest Neil Tennant/Chris Lowe "Battleship Potemkin", Institute "Distort Yourself", Bob Dylan "No Direction Home", Jem "Finally Woken", Machine Men "Elegies", Jamie Cullum "Catching Tales", Bloodhound Gang "Hefty Fine"

  20. Microsoft võttis Eesti koostööpakkumise vastu / Kristjan Otsmann

    Index Scriptorium Estoniae

    Otsmann, Kristjan, 1971-

    2004-01-01

    Ida-Euroopa riikide ja Microsofti ümarlaud Slovakkias Bratislavas. Microsofti asutaja Bill Gates oli huvitatud Meelis Atoneni ettepanekust, et riik korraldab oma kodanikele Microsofti tarkvara rentimise neile vastuvõetava hinnaga

  1. Studia Generalia "Mõisteloomest ja tähistamisest"

    Index Scriptorium Estoniae

    2007-01-01

    Studia Generalia loengus vaadeldakse erinevaid tähistamisteooriaid ning esitatakse neil põhinev mudel, mille abiga saab kultuurinähtuste analüüsis seostada nende kogemuslikke ja keelelisi aspekte

  2. Kas sul on see film juba nähtud? / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2009-01-01

    Gavin Hoodi lavastatud uusim film "X-meeste" sarjast, "X-meeste algus : Wolverine", on enne esilinastust lekkinud internetti. Lühidalt ka teistest aegsalt internetti lekkinud filmidest ja kuidas see neile mõjus

  3. Agriculture in S.A.: what of its future?

    OpenAIRE

    Smith, Neil

    2018-01-01

    Lecture given by Mr Neil Smith, Farmer - Maitland, Chair - Soil Conservation Council of S.A., Member - Grains Research and Development Corporation at the Waite Campus, University of Adelaide, 3.4.1996

  4. Slovarnõi zapass; Utrennjaja muzõka; Mõsl; Absoljutnõi jumor : tshitaja Jannisa Ritsosa; Ne prihhodi; Ne pomnju; Svet vdohnovenja; 'Kogda ot imeni tehh...'; 'Kto szhalitsja kto pozhalejet tehh...'; 'Na povorote skrezheshtshet tramvai...'; Prosto

    Index Scriptorium Estoniae

    Traat, Mats, 1936-

    1996-01-01

    Orig.: Sõnavara; Hommikumuusika; Mõte; Absoluutne huumor : Jannis Ritsost lugedes; Ära tule; Ei mäleta; "Kui nende nimel..."; "Kes heidab armu neile..."; "Pöörakul krigiseb tramm..."; Lihtsa naise elu

  5. Starting statistics: a short, clear guide

    National Research Council Canada - National Science Library

    Burdess, Neil

    2010-01-01

    ...." "In this refreshing book, experienced author and academic Neil Burdess shows that statistics are not the result of some mysterious "black magic", but rather the result of some very basic arithmetic...

  6. Pangad õhutavad III pensionisambaga liituma / Toivo Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2004-01-01

    Pangad peavad III pensionisambaga liitumist hädavajalikuks neile, kes soovivad oma elustandardit pensionile minnes säilitada. Pankade prognoose III sambaga liitumise kohta käesolevaks aastaks. Lisa: Pensioniks kogumine

  7. Eesti Gaasile võib langeda kohustus maksta hüvitist / Andrus Karnau, Hindrek Riikoja

    Index Scriptorium Estoniae

    Karnau, Andrus

    2006-01-01

    Majandusministeerium plaanitava regulatsiooni järgi tuleb Eesti Gaas AS-il maksta hüvitist neile tarbijatele ja klientidele, kelle firma tekkinud raskuste korral võrgust lahti ühendab. Gaasitarnest Eestis

  8. Plaadid / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2002-01-01

    Heliplaatide Linkin Park "Reanimation", Neil Young "Are You Passionate?", Rainbow "All Night Long", Gianluigi Trovesi "Dedalo", Oasis "Heathen Chemistry", Blind Guardian "A Night At The Opera", ZLO "Machopask", "Chill: Classical" arvustus

  9. Kallas sõidab Prodiga kohtuma / Jaanus Piirsalu

    Index Scriptorium Estoniae

    Piirsalu, Jaanus, 1973-

    2004-01-01

    Siim Kallas hakkab Euroopa Komisjoni presidendi Romano Prodiga arutama oma võimalikke töövaldkondi komisjonis. Kallasega soovivad kohtuda rahandusvolinik Pedro Solbes ja infotehnoloogiavolinik Erkki Liikanen, samuti komisjoni asepresident Neil Kinnock

  10. Eva manipulirujet Adamom / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2007-01-01

    11. veebr. Drugoi Teatris esietendunud Neil LaBute'i näidendist "Tshto potshjom" ("The shape of things"), lavastaja Johann Bott (Prantsusmaa). Osades Andrei Perovitsh, Jekaterina Nikolajeva, Zaven Ioannesjan ja Anastassija Solovjova

  11. Luupaljas hüljesnaine ja mineviku vangid / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013

    2010-01-01

    PÖFFi filmidest: Neil Jordani "Undiin" (Iirimaa - USA, 2009), Debra Graniku "Luupaljas" (USA, 2010), Urszula Antoniaki "Ei midagi isiklikku" (Iirimaa - Holland, 2009) ja Juan Jose Campanella "Saladus nende silmades" (Hispaania - Argentiina, 2009)

  12. a review of cyclopentadienyl type ligands in group 4 metallocene

    African Journals Online (AJOL)

    Neil Grimmer

    The Design of Group 4 Cyclopentadienyl, Olefin-Polymerisation Catalysts. Neil E. Grimmer ... Introduction and Historical Perspective. 120. 2. The Nature of .... before convincing evidence supporting this theory was published. Prior to this many.

  13. Issues in treating depression in primary care

    African Journals Online (AJOL)

    Correspondence to: N R Horn (doctor.neil.horn@gmail.com). Overview ... information through the internet have led ... depressed patients present with are not readily identifiable on diagnostic checklists, and include relationship problems (often.

  14. Alkhurma Hemorrhagic Fever in Saudi Arabia

    Centers for Disease Control (CDC) Podcasts

    This podcast looks at the epidemiologic characteristics of Alkhurma Hemorrhagic Fever in humans in Najran City, Saudi Arabia. CDC epidemiologist Dr. Adam MacNeil discusses the severity and risk factors for the illness.

  15. Üks vapper Jodie / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2007-01-01

    Mängufilm "Üks vapper naine" ("The Brave One") : režissöör Neil Jordan : peaosas Jodie Foster : Ameerika Ühendriigid - Austraalia 2007. Lisatud nimekiri "Jodie Fosteri menukamad filmid Põhja-Ameerikas"

  16. Ikka veel osaliselt väge täis / Veiko Märka

    Index Scriptorium Estoniae

    Märka, Veiko, 1964-

    2009-01-01

    Rakvere teatri lavastustest : Eric-Emmanuel Schmitt "Kooselu väikesed kuriteod", lavastaja Erki Aule; Neil Simon "Meie, mehed", lavastaja Toomas Suuman ja Ernest Hemingway "Ja päike tõused", lavastaja Jaaniks Juhanson

  17. Evaluation of Adaptive Signal Control Technology—Volume 2 : Comparison of Base Condition to the First Year After Implementation

    Science.gov (United States)

    2018-05-01

    Field evaluation of adaptive signal control technologies (ASCT) is very important in understanding the systems contribution to safety and operational efficiency. Data were collected at six intersections along the Neil Street corridor in Champaign,...

  18. Kümne kriitiku portreed / Andres Kurg

    Index Scriptorium Estoniae

    Kurg, Andres, 1975-

    2001-01-01

    Raamatust: 10 x 10 : 10 critics, 100 architects / autorid: Haig Beck, Jackie Cooper, Aaron Betsky, Roger Connah, Kristin Feireiss, Jorge Glusberg, Tom Heneghan, Mohsen Mostafavi, Terence Riley, Jaime Salazar, Neil Spiller. London : Phaidon, 2001

  19. Tasuta online-raamatud

    Index Scriptorium Estoniae

    2008-01-01

    Kirjastus HarperCollins paiskab kuuks ajaks internetti täistekstid Paulo Coelho loomingust. Kirjastus Random House pakub lugejatele väikese tasu eest vaid teatud peatükke näiteks Neil Gaimani loomingust

  20. South Local Government Area, Delta S

    African Journals Online (AJOL)

    ADOWIE PERE

    environs, Aniocha- South Local Government Area of Delta State, Nigeria was carried out with a view to determining the ... supply for physical industrial development to achieve maximum human .... the Schlumberger O' Neil software package.

  1. Õpetajatöö hindamine ja tagasiside / Kairit Kall

    Index Scriptorium Estoniae

    Kall, Kairit

    2014-01-01

    OECD rahvusvahelise õpetamise ja õppimise võrdlusuuringust (TALIS) 2013, milles antakse ülevaade koolijuhtide hinnanguil põhinevast formaalsest õpetajatöö hindamisest ning õpetajate hinnangutest sellele, kes ja mil viisil neile tagasisidet on andnud

  2. Juhtimiskonsultant: Q Vara saneerimiskava kui õudusunenägu / Anne Oja

    Index Scriptorium Estoniae

    Oja, Anne, 1970-

    2009-01-01

    Võlgades Q Vara küsib võlakirjainvestoritelt nelja-aastast armuaega ning õigust maksta laenud tagasi siis, kui neile kinnisvara müügist raha laekub. Vt. samas: Q Vara võlausaldajad kannavad kaotusi

  3. Congenital syphilis

    Science.gov (United States)

    ... following blood tests: Fluorescent treponemal antibody absorbed test ( FTA-ABS ) Rapid plasma reagin ( RPR ) Venereal disease research ... 2015 Updated by: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School ...

  4. "Beowulf" : Hollywood seikleb pimedas keskajas / Riho Laurisaar

    Index Scriptorium Estoniae

    Laurisaar, Riho

    2007-01-01

    Anglosaksi eeposest "Beowulf", mille alusel on valminud USA seiklusfilm, millest suur osa on loodud arvutigraafika abil ( stsenarist Neil Gaiman, režissöör Robert Zemeckis, osades Anthony Hopkins, Angelina Jolie, Ray Winstone)

  5. Hiinas tunda krahhi hõngu / Romet Kreek

    Index Scriptorium Estoniae

    Kreek, Romet, 1972-

    2010-01-01

    Hiinas ei tohi pangad anda laenu kolmanda eluaseme ostuks. Pankadele on soovitatud mitte anda kinnisvaralaenu mitteresidentidest maksutuludeta inimestele ja neile, kel ei ole tõendit sotsiaalmaksu tasumise kohta. Euroopas langesid lennifirmade aktsiad umbes 5%

  6. a case study of society's expectations of the schools curriculum in ...

    African Journals Online (AJOL)

    Erna Kinsey

    parents are definitely particular about the religious/moral instruction of their children. .... O'Neil observed that the North American education system, within the .... skills and these include Japan, Korea, China, Canada, England,. Germany ...

  7. Kaheksakümnendate eesti fotost = Estonian photography in the eighties / Peeter Laurits

    Index Scriptorium Estoniae

    Laurits, Peeter, 1962-

    2010-01-01

    Fotograafiast, fotoklubidest ja fotorühmitustest, fotograafidest ja nende vormiotsingutest, sotsiaalse ja nn. salongliku suuna esindajate vahelistest probleemidest ja diskussioonidest teemal "Kas fotokunst on kunst?" Neil aastail hakkas eesti fotokunst väljuma kultuurilisest isolatsioonist

  8. Er vi ved at date os til døde?

    DEFF Research Database (Denmark)

    Andersen, Tem Frank

    2014-01-01

    Den amerikanske kulturkritiker Neil Postman skrev tilbage i 1970'erne om fjernsynets indflydelse på vores forstand, vores kognitive kompetencer, vores kulturelle præferencer og i bund og grund om vores civilisations intellektuelle tilstand....

  9. Pop / Maria Ulfsak

    Index Scriptorium Estoniae

    Ulfsak, Maria, 1981-

    2007-01-01

    Heliplaatidest: Mando Diao "Never Seen the Light of Day", Joyce & Tutty Moreno "Samba Jazz & Outras Bossas", Neil Young "Chrome Dreams II", John Fogerty "Revival", Opium Flirt "Tehislend", Joni Mitchell "Shine", Serj Tankian "Elect the Dead"

  10. Harry Tillmann / B. T., J. K.

    Index Scriptorium Estoniae

    Tesnov, Boris, 1912-2003

    1992-01-01

    Mitme Saksa ülikooli juures veterinaargünekoloogia professorina töötanud H. Tillmann käis ka korduvalt Lähis-Ida ja Aafrika riikides põllumajanduse korrladust uurimas, et neile abi andmist korraldada

  11. Avariide kiuste Monte Carlosse / Aare Arula

    Index Scriptorium Estoniae

    Arula, Aare

    2007-01-01

    Vt. ka Tehnika dlja Vsehh nr. 3, lk. 26-27. 26. jaanuaril 1937 Tallinnast Monte Carlo tähesõidule startinud Karl Siitanit ja tema meeskonda ootasid ees seiklused, mis oleksid neile peaaegu elu maksnud

  12. USA president näeb Ukrainat ja Gruusiat alliansi liikmetena / Krister Paris

    Index Scriptorium Estoniae

    Paris, Krister, 1977-

    2008-01-01

    USA president George W. Bush toetab Ukraina ja Gruusia püüdlusi saada NATO liikmesuse tegevuskava (MAP), Prantsusmaa ja Saksamaa on neile riikidele MAP-i andmise vastu. Riikidest, kellele on NATO valmis andma liitumiskutse

  13. Mapping QTL for fatty acid composition that segregates between the ...

    African Journals Online (AJOL)

    Mapping QTL for fatty acid composition that segregates between the Japanese Black and Limousin cattle breeds (Short communication). NOM Tshipuliso, LJ Alexander, TW Geary, VM Snelling, DC Rule, JE Koltes, BE Mote, MD MacNeil ...

  14. Evaluation of Groundwater Potentials for Borehole Drilling by ...

    African Journals Online (AJOL)

    ADOWIE PERE

    presented as depth sounding curves and were suitably iterated using Schlumberger O'Neil software. .... Data Processing and Data Interpretation: The VLF-. EM data in addition .... and sharpness, suggesting the presence of a shallow and deep ...

  15. ORIGINAL ARTICLES

    African Journals Online (AJOL)

    Graham Michael Behr, Cathy Christie, Neil Soderlund,. Tennyson Lee ..... Lyons JS, O' Mahoney MT, Miller SI, et al. Predicting ... Neuring E, Thayer J, Lander R. On the factors predicting rehospitalisation among two state mental hospital ...

  16. Ema, kes hõikab poja järele / Kätlin Kaldmaa

    Index Scriptorium Estoniae

    Kaldmaa, Kätlin, 1970-

    2007-01-01

    Arvustus: Jordan, Neil. Vari / tõlkinud Krista Kaer. Tallinn : Varrak, 2006 ; McCall Smith, Alexander. Unenägude Angus : keldi unenägude jumal / inglise keelest tõlkinud Kätlin Kaldmaa. [Tallinn] : Eesti Päevaleht, 2007

  17. The American Dramatist's Vision of the 1950s / Annika Namme

    Index Scriptorium Estoniae

    Namme, Annika

    2004-01-01

    Ameerika näitekirjanike Arthur Milleri ("The Crucible", 1953) ja Edward Albee ("The Death of Bessie Smith" 1959, "The American Dream" 1961) näidendite näitel. Kogumiku koostajad on Neil Murray ja Tony Thorne

  18. Multiple Sclerosis: Hope Through Research | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Multiple Sclerosis Hope Through Research Past Issues / Spring 2012 Table ... that television journalist Neil Cavuto was diagnosed with multiple sclerosis (MS) more than 15 years ago. And that ...

  19. Rakvere teater lahkab (koos)elu

    Index Scriptorium Estoniae

    2009-01-01

    Rakvere teatri kevadhooaja kolme esietenduse tutvustus: Eric-Emmanuel Schmitt "Kooselu väikesed kuriteod", lavastaja Erki Aule, Neil Simon "Meie, mehed", lavastaja Toomas Suuman ja Ernest Hemingway "Ja päike tõuseb", lavastaja Jaanika Juhanson

  20. Astronauts Armstrong and Scott arrive at Hickam Field, Hawaii

    Science.gov (United States)

    1966-01-01

    Astronauts Neil A. Armstrong (center), command pilot, and David R. Scott, pilot, arrive at Hickam Field, Hawaii on their way from Naha, Okinawa, to Cape Kennedy, Florida. Astronaut Walter M. Schirra Jr. is at extreme left.

  1. Pro ljudei i pro aktjorov / Svetlana Jantshek

    Index Scriptorium Estoniae

    Jantšek, Svetlana

    2000-01-01

    Vene Draamateatri peanäitejuht Eduard Toman ja näitleja Herardo Kontreras arutavad viimase juubelilavastuseks valitud Neil Simoni näidendit "Päikesepoisid", kus nad mõlemad kavatsevad mängida ja E. Toman ka lavastada

  2. CSIR R&D in emerging manufacturing technologies

    CSIR Research Space (South Africa)

    Trollip, Neil

    2017-10-01

    Full Text Available This presentation discusses Advanced Robotics and Emerging manufacturing technologies by Dr Neil Trollip, at the 6th CSIR Conference: Ideas that work for industrial development, 5-6 October 2017, CSIR International Convention Centre, Pretoria...

  3. Indigolapsed muudavad maailma / Moon Meier

    Index Scriptorium Estoniae

    Meier, Moon

    2004-01-01

    Kasvatusteadlased avastasid, et alates u 1980. a-st sündinud lapsed on hoopis teistsugused kui eelmised põlvkonnad. Senine haridussüsteem neile ei sobi, hariduses peaks rohkem pöörama tähelepanu emotsioonidele

  4. Circumcision

    Science.gov (United States)

    ... have an increased risk of certain conditions, including: Cancer of the penis Certain sexually transmitted diseases, including HIV Infections of ... 2016:chap 40. Review Date 10/18/2017 Updated by: Neil K. Kaneshiro, MD, MHA, Clinical Professor ...

  5. Go4Life

    Medline Plus

    Full Text Available ... Biomarkers and Alzheimer's Disease: Dr. Neil Buckholtz - Duration: 6 minutes, 34 seconds. National Institute On Aging 7, ... next Play now Choosing Nutrient Dense Foods - Duration: 6 minutes, 19 seconds. National Institute On Aging 16, ...

  6. Assessment of hairy roots induction in Solenostemon scutellarioides ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-08-04

    Aug 4, 2009 ... family (Garcia and O'Neil, 2000). Cell suspension and transformed callus cultures of this plant are known to produce rosmarinic acid ... Hairy root is a pathological syndrome of dicotyledonous plants following wounding and ...

  7. Plaadid / Priit Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Priit, 1957-

    2005-01-01

    Uutest heliplaatidest Neil Young "Prairie Wind", Sigur Ros "Takk...", Paul McCartney "Chaos and Creation in the Backyard", Lauri Saatpalu, Katrin Mandel "Sa oled hea", "Rock2005", The Corrs "Home", Dandy Warhols "Odditorium or Warlords of Mars"

  8. Eesti kirjastused Facebookis / Maris Nool

    Index Scriptorium Estoniae

    Nool, Maris

    2012-01-01

    Artikkel selgitab välja kirjastuste Facebooki veebilehtede sisu tunnused ning neile osaks saava tähelepanu veebruarist aprillini 2012. Valimi moodustasid TEA Kirjastus, kirjastused Pegasus, Fantaasia, Sinisukk, Tallinna Ülikooli Kirjastus, Allika Kirjastus ja Mantra Kirjastus

  9. 77 FR 44310 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2012-07-27

    ... JACINTA YEUNG CHEONG CHANG MICHAEL YIO-HOW CHENG NICOLAS VINCENT CHI TELLY TAI HSUAN CHINOY SAMIR MUSTAPHA... TONJA YVONNE SU JIN CHIN SU XIAOBO SARA SHAO SUEN SAMSON C. L. SY KEVIN NEIL TAN LAI HING THARALDSEN...

  10. Poliitikud kaitsevad saadikute kulude hüvitamise süsteemi / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2006-01-01

    Erakondade juhtpoliitikud on rahul praeguse parlamendiliikmete kulude hüvitamise süsteemiga, mille kohaselt hüvitatakse neile kuludokumentide alusel kulutused kuni 30 protsendi ulatuses palgast. Vt. samas: Tuuli Koch. Künka kosilased. Lisa: Hea teenistus

  11. Prenatal diagnosis of two fetuses with deletions of 8p23.1, critical region for congenital diaphragmatic hernia and heart defects.

    Science.gov (United States)

    Keitges, Elisabeth A; Pasion, Romela; Burnside, Rachel D; Mason, Carla; Gonzalez-Ruiz, Antonio; Dunn, Teresa; Masiello, Meredith; Gebbia, Joseph A; Fernandez, Carlos O; Risheg, Hiba

    2013-07-01

    Microdeletions of 8p23.1 are mediated by low copy repeats and can cause congenital diaphragmatic hernia (CDH) and cardiac defects. Within this region, point mutations of the GATA4 gene have been shown to cause cardiac defects. However, the cause of CDH in these deletions has been difficult to determine due to the paucity of mutations that result in CDH, the lack of smaller deletions to refine the region and the reduced penetrance of CDH in these large deletions. Mice deficient for one copy of the Gata4 gene have been described with CDH and heart defects suggesting mutations in Gata4 can cause the phenotype in mice. We report on the SNP microarray analysis on two fetuses with deletions of 8p23.1. The first had CDH and a ventricular septal defect (VSD) on ultrasonography and a family history of a maternal VSD. Microarray analysis detected a 127-kb deletion which included the GATA4 and NEIL2 genes which was inherited from the mother. The second fetus had an incomplete atrioventricular canal defect on ultrasonography. Microarray analysis showed a 315-kb deletion that included seven genes, GATA4, NEIL2, FDFT1, CTSB, DEFB136, DEFB135, and DEFB134. These results suggest that haploinsufficiency of the two genes in common within 8p23.1; GATA4 and NEIL2 can cause CDH and cardiac defects in humans. Copyright © 2013 Wiley Periodicals, Inc.

  12. Mida usud, seda lõikad / Mart Raudsaar

    Index Scriptorium Estoniae

    Raudsaar, Mart, 1973-

    2003-01-01

    Autori sõnul on ka keskpäraste töötajatega erakordsete tulemuste saavutamine võimalik: tööandjal tuleb oma ootustest vihjete abil teada anda ning inimesed reageerivad neile oma käitumist vastavalt kohandades

  13. Volshebnik izumrudnogo ostrova / Nikolai Karajev

    Index Scriptorium Estoniae

    Karajev, Nikolai, 1978-

    2007-01-01

    Iiri režissöör ja kirjanik Neil Jordan, kes viibis 2006.a. detsembris Tallinnas seoses 10. Pimedate Ööde Filmifestivaliga. Pikemalt tema filmist "Hommikusöök Pluutol" ("Breakfast on Pluto") : Suurbritannia-Iirimaa 2005

  14. The relative importance of fluid and kinetic frequency shifts of an electron plasma wave

    International Nuclear Information System (INIS)

    Winjum, B. J.; Fahlen, J.; Mori, W. B.

    2007-01-01

    The total nonlinear frequency shift of a plasma wave including both fluid and kinetic effects is estimated when the phase velocity of the wave is much less than the speed of light. Using a waterbag or fluid model, the nonlinear frequency shift due to harmonic generation is calculated for an arbitrary shift in the wavenumber. In the limit where the wavenumber does not shift, the result is in agreement with previously published work [R. L. Dewar and J. Lindl, Phys. Fluids 15, 820 (1972); T. P. Coffey, ibid. 14, 1402 (1971)]. This shift is compared to the kinetic shift of Morales and O'Neil [G. J. Morales and T. M. O'Neil, Phys. Rev. Lett. 28, 417 (1972)] for wave amplitudes and values of kλ D of interest to Raman backscatter of a laser driver in inertial confinement fusion

  15. The relative importance of fluid and kinetic frequency shifts of an electron plasma wave

    Science.gov (United States)

    Winjum, B. J.; Fahlen, J.; Mori, W. B.

    2007-10-01

    The total nonlinear frequency shift of a plasma wave including both fluid and kinetic effects is estimated when the phase velocity of the wave is much less than the speed of light. Using a waterbag or fluid model, the nonlinear frequency shift due to harmonic generation is calculated for an arbitrary shift in the wavenumber. In the limit where the wavenumber does not shift, the result is in agreement with previously published work [R. L. Dewar and J. Lindl, Phys. Fluids 15, 820 (1972); T. P. Coffey, Phys. Fluids 14, 1402 (1971)]. This shift is compared to the kinetic shift of Morales and O'Neil [G. J. Morales and T. M. O'Neil, Phys. Rev. Lett. 28, 417 (1972)] for wave amplitudes and values of kλD of interest to Raman backscatter of a laser driver in inertial confinement fusion.

  16. Alternative approaches to evaluation of cow efficiency | MacNeil ...

    African Journals Online (AJOL)

    Estimated breeding values based on the preceding results and using the maternal genetic effect on ADG as a proxy for the direct genetic effect on milk production were combined in six indexes of cow efficiency. These indexes sought to increase output and decrease input simultaneously, to increase output holding input ...

  17. How to use an inhaler - with spacer

    Science.gov (United States)

    ... peak flow a habit! Signs of an asthma attack Stay away from asthma triggers Review Date 2/15/2016 Updated by: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. ...

  18. How to use a nebulizer

    Science.gov (United States)

    ... peak flow a habit! Signs of an asthma attack Stay away from asthma triggers Review Date 2/15/2016 Updated by: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. ...

  19. Dimedone Derivative

    African Journals Online (AJOL)

    1Department of Oncology, The Second Affiliated Hospital, Medical school of Xi'an Jiaotong University, Xi'an ... A, and similar functionality of test drug, the effect ... Oral. Ibuprofen suspension was purchased as Motrin. (100 mg/ 5ml; McNeil).

  20. Establishing a conversion factor between electrical conductivity and ...

    African Journals Online (AJOL)

    2015-07-04

    Jul 4, 2015 ... In large areas of South Africa, acid mine drainage (AMD) from gold, coal ..... salinity (Scofield and Wilcox, 1931; Rainwater and Thatcher,. 1960; McNeil .... sites belonging to different river systems, but varied little for individual ...

  1. Kehv mälu viitab insuldiohule / tõlkinud Kalle Klein

    Index Scriptorium Estoniae

    2010-01-01

    Eakate seas läbi viidud uuringust mis näitas, et inimesed, kellel esineb mälukaotust või mõtlemisvõime nõrgenemist, võivad kuuluda insuldi riskirühma, olenemata sellest, kas neil on diagnoositud dementsus

  2. London tõukas New Yorgi troonilt / Kertu Ruus

    Index Scriptorium Estoniae

    Ruus, Kertu, 1977-

    2007-01-01

    Maailma finantskeskuste indeksi järgi on London tõuganud New Yorgi teisele kohale, neile järgnevad Hongkong, Singapur ja Zürich. Vt. samas: IPOd on USAs kokku kuivanud. Tabel: Londoni börsile tuli mullu rohkem firmasid

  3. Hantavirus Pulmonary Syndrome

    Centers for Disease Control (CDC) Podcasts

    2011-07-14

    Dr. Adam MacNeil, epidemiologist with Viral Special Pathogens Branch at CDC, discusses hantavirus pulmonary syndrome.  Created: 7/14/2011 by National Center for Emerging Zoonotic and Infectious Diseases (NCEZID).   Date Released: 7/18/2011.

  4. Astronauts Armstrong and Scott during photo session outside KSC

    Science.gov (United States)

    1966-01-01

    Astronauts Neil A. Armstrong (left), command pilot, and David R. Scott, pilot, the Gemini 8 prime crew, during a photo session outside the Kennedy Space Center (KSC) Mission Control Center. They are standing in front of a radar dish.

  5. Riigikogu maine ja armastus / Aune Past

    Index Scriptorium Estoniae

    Past, Aune, 1954-

    2007-01-01

    Autor arutleb Riigikogu maine üle, toetudes TÜ ajakirjanduse ja kommunikatsiooni osakonna 2007. aastal tehtud uuringu tulemustele. Riigikogu liikmete maine paraneks, kui neil endil oleks selge, mis eesmärgil Toompeale mindi ja sellest siis ka rahvale kõneldaks

  6. Comet prospects for 2004

    Science.gov (United States)

    Shanklin, J. D.

    2003-12-01

    2004 sees the return of 18 periodic comets. None are particularly bright and the best are likely to be 78P/Gehrels and 88P/Howell. Three new long period comets are likely to put on a good show: 2001 Q4 (NEAT) reaches perihelion in May, when it could make at least 3rd magnitude. Northern hemisphere observers will first pick it up just after perihelion as it rapidly moves north. 2002 T7 (LINEAR) could also reach 3rd magnitude at closest approach in May, however northern hemisphere observers will have lost it as a binocular object in mid-March. Observers at far southern latitudes may be able to see these two naked eye comets at the same time. 2003 K4 (LINEAR) could reach 6th magnitude as it brightens on its way to perihelion. Several other long period comets discovered in previous years are also still visible.

  7. Chavez ähvardab terroristi tapnud Colombiat sõjaga / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2008-01-01

    Colombia sõdurid tapsid Ecuadoris mässulisi ning võtsid endaga kaasa terroristliku punaarmee FARC tähtsuselt teise mehe. Colombia väitel on neil tõendeid Ecuardori valitsuse koostöö kohta Colombia mässulistega. Kaart

  8. Viewpoint: Back to the Basics in Social Studies? Personal Statements by Three Canadian Educators

    Science.gov (United States)

    Sutherland, Neil; And Others

    1977-01-01

    Neil Sutherland discusses the historical context of the back to basics movement in social studies. Ken Osborne points out that the movement is stifling innovation. Max van Manen addresses the question of what curricula should be considered basic. (Author/RM)

  9. Code-switched English pronunciation modeling for Swahili spoken term detection

    CSIR Research Space (South Africa)

    Kleynhans, N

    2016-05-01

    Full Text Available Computer Science 81 ( 2016 ) 128 – 135 5th Workshop on Spoken Language Technology for Under-resourced Languages, SLTU 2016, 9-12 May 2016, Yogyakarta, Indonesia Code-switched English Pronunciation Modeling for Swahili Spoken Term Detection Neil...

  10. "Biloxi blues" on näidend saatusest - hõlmamatust ja isepäisest mehhanismist, mida saab alles tagantjärele mõista / Sander Pukk ; intervjueerinud Maria Lee Liivak

    Index Scriptorium Estoniae

    Pukk, Sander, 1984-

    2011-01-01

    EMTA Lavakunstikooli 3. kursusel lavastajaks õppiv Sander Pukk Neil Simoni näidendi "Biloxi blues" lavastamisest Tallinna Linnateatris, lavastusest, lavastamise võlust. Mängivad lavakunstikooli 25. lennu üliõpilased ning Tallinna Linnateatri näitlejad, esietendus 2.04.2011

  11. Microwave-irradiation polyol synthesis of PVP-protected Pt–Ni electrocatalysts for methanol oxidation reaction

    CSIR Research Space (South Africa)

    Mathe, Ntombizodwa R

    2017-01-01

    Full Text Available ://doi.org/10.1007/s12678-017-0441-3 Microwave-Irradiation Polyol Synthesis of PVP-Protected Pt–Ni Electrocatalysts for Methanol Oxidation Reaction Ntombizodwa R. Mathe Manfred R. Scriba Rirhandzu S. Rikhotso Neil J. Coville ABSTRACT: Bimetallic Pt...

  12. Go4Life

    Medline Plus

    Full Text Available ... 34 Play next Play now Biomarkers and Alzheimer's Disease: Dr. Neil Buckholtz - Duration: 6 minutes, 34 seconds. National ... all 4:33 Play next Play now Alzheimer's Disease Clinical Trials: Dr. Laurie Ryan - Duration: 4 minutes, 33 seconds. National ...

  13. Pop / Lauri Tikerpe

    Index Scriptorium Estoniae

    Tikerpe, Lauri

    2005-01-01

    Heliplaatidest: Little Brother "The Minstrel Show", Jackson and his Computer Band "Smash", Matthew Herbert "Plat du Jour", Porn Sword Tobacco "Explains Freedom", Jamiroquai "Dynamite", Ryan Adams and the Cardinals "Jacksonville City Nights", The Dandy Warhols "Odditorium", Neil Young "Prairie Wind"

  14. IT-firmad pääsevad pooleks aastaks Silicon Valleysse / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2010-01-01

    Tehnopol ja EAS toetavad nn. start-up-firmade saatmist pooleks aastaks USA-sse Silicon Valleysse kogemusi omandama, programm on mõeldud eelkõige neile ettevõtetele, kel on oma toode või teenus valmis ja kes soovivad sellega maailmaturule minna

  15. Pop / Lauri Tikerpe

    Index Scriptorium Estoniae

    Tikerpe, Lauri

    2006-01-01

    Heliplaatidest: The Kooks "Inside In/Inside Out", Neil Diamond "12 Songs", Layo & Bushwacka "Feels Closer", Roots Manuva "Alternately Deep", The Streets "The Hardest Way To Make An Easy Living", Paul Simon "Surprise", Dead Next Door "Time to Fight", Ketaspidur "Mis Mõttes?"

  16. The end of the subordinate worker? The on-demand economy, the gig economy, and the need for protection for crowdworkers / Adrian Todoli-Signes

    Index Scriptorium Estoniae

    Todoli-Signes, Adrian

    2017-01-01

    Töötajatest tulevikus, äriühingute muutumisest digitaalmaailmas ja füüsilisest isikust ettevõtjatest; töötajate kaitsmisest tööturul ja neile rakenduvatest tööseadustest; Uber'ist ja Amazon Mechanical Turk'ist

  17. Tubakamüüja süüdistab riiki kahju tekitamises / Kadrin Karner ; kommenteerinud Hille Reinhold

    Index Scriptorium Estoniae

    Karner, Kadrin

    2010-01-01

    British American Tobacco Estonia ja Eesti Kaupmeeste Liit taotlesid riigilt vana maksumärgiga tubakatoodete müümistähtaja pikendamist kolmelt kuult kuuele. Kuna valitsus ettepanekut ei toetanud, leiab firma, et riik tekitas neile kahju 6,6 miljonit krooni

  18. airBaltic claims to be subsidizing Ryanair

    Index Scriptorium Estoniae

    2010-01-01

    Riia lennujaama väitel võlgneb airBaltic neile 3,5 miljoni euro väärtuses lennujaamatasusid ning annab lennufirma kohtusse. airBaltic on aga lennujaama diskrimineeriva käitumise tõttu pöördunud konkurentsiameti poole

  19. Key pipeline drips dry

    Index Scriptorium Estoniae

    2003-01-01

    Venemaa kütusefirma Transneft lõpetas naftaekspordi läbi Ventspilsi sadama, kuna Läti kütusefirma Vetspils Oil polnud nõus neile oma aktsiaid müüma. EL sekkub Venemaa ja Läti kütusefirmade vahelisse vaidlusse

  20. A Case of Ebola Virus

    Centers for Disease Control (CDC) Podcasts

    2012-10-01

    Dr. Adam MacNeil, an epidemiologist at CDC, discusses Ebola virus.  Created: 10/1/2012 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID); National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 10/1/2012.

  1. Aas : pole vahet, kas odavalt korteri saajal on kinnisvara või mitte / Taavi Aas ; interv. Urmas Seaver

    Index Scriptorium Estoniae

    Aas, Taavi, 1966-

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 2. märts 2007, lk. 8. Tallinna abilinnapea sõnul ei pea linn vajalikuks uurida, kas turuhinnast palju odavamalt kortereid saavatel inimestel on juba kinnisvara, sest nii hüvitatakse neile omandireformiga tehtud ülekohut

  2. Patterns and determinants of acute psychiatric readmissions | Behr ...

    African Journals Online (AJOL)

    Patterns and determinants of acute psychiatric readmissions. Graham Michael Behr, Cathy Christie, Neil Soderlund, Tennyson Lee. Abstract. Objectives. Deinstitutionalisation and shortage of psychiatric beds worldwide has led to extensive research into the risk factors and interventions associated with rapid and recurrent ...

  3. Välisminister Urmas Paeti soovitus narvalastele : "Jälgige erinevaid infokanaleid!" / Kirill Smirnov

    Index Scriptorium Estoniae

    Smirnov, Kirill

    2008-01-01

    Ilmunud ka: Severnoje Poberezhje 4. sept., lk. 1. Narvas viibinud välisminister Urmas Paet kutsus piirilinlasi üles neile ajalehtedes ja televisioonis pakutavasse informatsiooni kriitiliselt suhtuma. Välisministri Narva-visiidi ajendiks oli Eesti eeslaste ja venelaste erinev suhtumine Gruusia-Osseetia konflikti

  4. Pensionifondi valik tuleb hoida lahus pakutavatest kingitustest / Aleksei Günter

    Index Scriptorium Estoniae

    Günter, Aleksei, 1979-

    2005-01-01

    Kuigi 31. oktoobril lõpeb 1965-1967 aastatel sündinud inimestel kohustusliku kogumispensioniga liitumise võimalus, ei ole neil aastatel Eestis sündinud ja elavast 51 715 inimesest 28. oktoobriks teise pensionisambaga liitunud 15 317 inimest. Diagrammid: Teise samba pensionifondid

  5. Proceedings of the Interservice/Industry Training Equipment Conference (4th) Held at Kissimmee, Florida on 15-18 November 1982. Volume 2

    Science.gov (United States)

    1982-01-01

    Ohio State University Craig , Charles D. 1501 Neil Avenue Training Devices Group Supervisor Columbus, OH 43202 Lockheed California Company P.O. Box...Manager Arlington, VA 22202 Maritime Administration U.S. Merchant Marine Academy Deegan , Paul A. Kingspoint, NY 11024 Editor-Military Simulators

  6. Vahetusüliõpilased Tallinnas piire ületamas / Hanneleen Pihlak

    Index Scriptorium Estoniae

    Pihlak, Hanneleen

    2008-01-01

    Jaanuarist märtsini õppis EMTA Lavakunstikoolis 16 vahetusüliõpilast Londoni teatrikoolist, Rose Brufordi kolledzhist. Näitlemisõppe lõputööna valmis neil õppejõudude Kärt Tominga ja Ingo Normeti juhendamisel Bertolt Brechti näidend "Kaukaasia kriidiring"

  7. Eesti diplomaadid jõudsid Süüriasse rattureid otsima / Kadri Ibrus, Ilmar Kahro

    Index Scriptorium Estoniae

    Ibrus, Kadri

    2011-01-01

    Liibanoni uudisteportaali Lebanon Files väitel saatis rühmitus Taassünni ja Reformi Liikumine neile uue e-kirja. Rühmitus teatab, et eestlased on elus ja hea tervise juures, ning nõuab lunaraha. Välisminister Urmas Paeti jt. kommentaare

  8. Norra parlamendiliikmed EML-il külas / Imbi E. Kaljuste

    Index Scriptorium Estoniae

    Kaljuste, Imbi E., 1963-

    2006-01-01

    Norra parlamendiliikmetele külaskäigul Eesti Maksumaksjate Liitu tutvustati neile Eesti maksusüsteemi kujunemist, selle positiivseid ja negatiivseid külgi, samuti vastati külaliste küsimustele, mis puudutasid tulumaksu, sotsiaalkindlustus- ning käibemaksusüsteemi

  9. Astronauts Armstrong and Aldrin study rock samples during field trip

    Science.gov (United States)

    1969-01-01

    Astronaut Neil Armstrong, commander of the Apollo 11 lunar landing mission, and Astronaut Edwin Aldrin, Lunar module pilot for Apollo 11, study rock samples during a geological field trip to the Quitman Mountains area near the Fort Quitman ruins in far west Texas.

  10. Raha varjatud hind / Peter Singer

    Index Scriptorium Estoniae

    Singer, Peter

    2008-01-01

    Kathleen Vohs, Nicole Mead ja Miranda Goode leidsid eksperimentide kaudu viisi, kuidas panna inimesed mõtlema rahast, ilma et neil seda otseselt teha kästaks. Rahast mõtlema suunatud katsealuste grupi käitumine erines suuresti teise grupi käitumisest

  11. Nicolas Cage otsib kadunud tütart naistesaarelt / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2006-01-01

    Õudusfilm "Ohvripidu" : režissöör Neil LaBute : peaosas Nicholas Cage : Ameerika Ühendriigid - Saksamaa 2006. Film on uusversioon briti 1973.a. filmist, mille režissöör oli Robin Hardy ja ühes peaosadest Christopher Lee

  12. Hallipäiste leegionid tulevad / Carolyn Moynihan ; tõlk. Ingrid Vooglaid

    Index Scriptorium Estoniae

    Moynihan, Carolyn

    2007-01-01

    Globaalsest vananemisest, Jaapani elanikkonna vananemisest ja vähenemisest. Autor leiab, et Lääs vajab üha rohkem tööjõudu teiste rahvaste hulgast ning õigus võib olla neil, kelle arvates võib Euroopa muutuda "Euraabiaks". Hiina ees seisvast vananemiskriisist

  13. Tallinna lennuväli jääb tõelisele hiiglasele kitsaks / Erik Rand

    Index Scriptorium Estoniae

    Rand, Erik

    2010-01-01

    Helsingi Vantaa lennuväljal maandus maailma suurim reisilennuk Airbus 380. AS-i Tallinna Lennujaam juhatuse esimehe Rein Loigu väitel käiks selle lennuki vastuvõtmine neil tehniliselt õle jõu, see lennuk vajab hoopis teistsuguse infrastruktuuriga lennujaamu. Põhitakistus on lennuraja kitsus

  14. International Criminal Law: Over-studied and Underachieving?

    NARCIS (Netherlands)

    van Sliedregt, E.

    2016-01-01

    In his recent review of Neil Boister's book, An Introduction to Transnational Criminal Law, Robert Currie praises the author for shedding light on a field of law that has suffered from inattention. Transnational criminal law (TCL), the 'other' branch of what was traditionally called international

  15. Salmonella causada por reptiles y anfibios en guarderías (Salmonella Infections Caused by Reptiles and Amphibians in Childcare Centers)

    Centers for Disease Control (CDC) Podcasts

    Traducción al español de la entrevista con el Dr. Neil Vora, funcionario del EIS de los CDC, sobre su artículo acerca de las infecciones por Salmonella causadas por reptiles y anfibios en guarderías.

  16. Apollo 11 Moon Landing

    Science.gov (United States)

    1969-01-01

    The crowning achievement for the Saturn V rocket came when it launched Apollo 11 astronauts, Neil Armstrong, Edwin (Buzz) Aldrin, and Michael Collins, to the Moon in July 1969. In this photograph, astronaut Aldrin takes his first step onto the surface of the Moon.

  17. Maternal preconception diet and the sex ratio

    NARCIS (Netherlands)

    Cramer, J.S.; Lumey, L.H.

    2009-01-01

    Temporal variations in the sex ratio or the ratio of boys over girls at birth have been widely studied and variously attributed to social changes, conditions of war, and environmental changes. Recently, Mathews, Johnson and Neil (2008) studied the direct evidence of individual pregnancies and

  18. Ülakorrusel tukub lunastaja, all ukerdab komöödia / Pille-Riin Purje

    Index Scriptorium Estoniae

    Purje, Pille-Riin, 1963-

    2006-01-01

    Eesti teatrites lavastatud komöödiatest - Karoly Szakonyi "Saateviga" Marko Matvere lavastuses Ugalas, Neil Simoni "Sekstett a la carte" Jüri Lumiste lavastuses Vanemuises, "Täismäng" Ingomar Vihmari lavastuses Rakvere Teatris, Geraldine Aroni "Minu oivaline abielu" Kaie Mihkelsoni lavastuses Eesti Draamateatris

  19. USA soovib relvatarnete abil vähendada Iraani mõjuvõimu / Jürgen Tamme

    Index Scriptorium Estoniae

    Tamme, Jürgen

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 31. juuli 2007, lk. 5. USA president George W. Bushi administratsioon soovib Kongressi heakskiitu plaanile, mis näeb ette Pärsia lahe piirkonnas asuvate USA liitlaste rahaliste toetuste suurendamist ja neile relvastuse saatmist. Lisa: USA tarned

  20. Neoliberalization, housing institutions and variegated gentrification: how the ‘third wave’ broke in Amsterdam

    NARCIS (Netherlands)

    van Gent, W.P.C.

    2013-01-01

    Neil Smith argues that in the last two decades gentrification has become a generalized global urban phenomenon. His theory is at a high level of abstraction, as it links urban gentrification to globalization, financial capitalism and neoliberalization. With these global processes, all cities have

  1. Salmonella Infections Caused by Reptiles and Amphibians in Childcare Centers

    Centers for Disease Control (CDC) Podcasts

    2013-02-07

    Dr. Neil Vora, an EIS Officer at CDC, discusses his article about Salmonella infections in childcare centers caused by reptiles and amphibians.  Created: 2/7/2013 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 2/7/2013.

  2. African Journal of Biotechnology - Vol 11, No 59 (2012)

    African Journals Online (AJOL)

    Mutational analysis of fructose-1,6-bisphosphate aldolase of Neisseria meningitidis serogroup B · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Sarfraz A Tunio, Neil J Oldfield, Karl G Wooldridge, David PJ Turner, 12269-12276 ...

  3. Effect of extracellular calcium chloride on sporangiospore-yeast ...

    African Journals Online (AJOL)

    User

    2011-05-16

    May 16, 2011 ... Bartnicki-Garcia and Nickerson (1962b) whereby it was shown that R. stolonifer .... A 7 day old culture of R. stolonifer was flushed with sterile deioni- zed distilled water and ..... Madi N, McNeil B, Harvey LM (1997). The effect of ...

  4. 75 FR 59706 - Coastal Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-09-28

    ... Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments... on July 16, 2010, Coastal Hydropower, LLC filed an application for a preliminary permit, pursuant to... generation of the project would be 7.9 gigawatt-hours. Applicant Contact: Neil Anderson, Coastal Hydropower...

  5. 77 FR 31349 - Coastal Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2012-05-25

    ... Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On April 12, 2012, Coastal Hydropower, LLC filed an... generation of 31.5 gigawatt-hours. Applicant Contact: Neil Anderson, Coastal Hydropower, LLC, Key Centre, 601...

  6. Eesti Miss teeb videofilmi / Evelyn Mikomägi ; interv. Valdo Jahilo

    Index Scriptorium Estoniae

    Mikomägi, Evelyn

    2001-01-01

    Eesti Miss Estonia 2000 Evelyn Mikomägi tegi koos sõbra, Sven-Olof Svenne Englundiga dokfilmi Küprosel peetud maailma suurimast iludusvõistlusest Miss Universe 2000. Neile kuulub ühisfirma "Living Frames" Rootsis, mille peategevus on suunatud 16mm ja 35mm filmide tootmisele

  7. Enhancements and Extensions of Formal Models for Risk Assessment in Software Projects

    Science.gov (United States)

    2002-09-01

    the five defect categories. Cosmetic Defects. The name that corresponds to QSM®’s cosmetic defects. Cosmetic defects can be described as deferred...California. June 2002. (Fent00) Fenton , N. E. and Neil, M., Software Metrics: Roadmap. Proceedings of the Conference on the Future of Software

  8. Pop / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2002-01-01

    Heliplaatidest Dungeon Family "Even In Darkness". Fatboy Slim "Live On Brighton Beach". X-Exutioners "Built From Scratch". Fila Brazillia "Jump Leads". Air "Everybody Herz". Billy Idol "VH1 Storytellers". Neil Halstead "Sleeping on Roads". The Soundtrack Of Our Lives "Behind The Music". si-cut.db "Enthusiast"

  9. Fossil fields of Ilmandu and Muraste north Estonia / Valter Lang, Helena Kaldre, Marge Konsa...[jt.

    Index Scriptorium Estoniae

    2004-01-01

    Imandu ja Muraste küla maadel on plaanistatud seni kõige suurem fossiilsete põldude jäänustega ala Eestis. Esindatud on eri tüüpi põllusüseemid. Maaharimise alguse neil aladel võib dateerida eelrooma rauaaega ning see kestis kuni uusajani

  10. Omavalitsuste rahastamise probleeme Eestis / Olev Raju

    Index Scriptorium Estoniae

    Raju, Olev, 1948-

    2003-01-01

    Ilmunud ka: Halduskultuur 2003 : teaduskonverentsi ettekanded = Administrative culture 2003 : conference papers . - Tallinn, 2004, lk. 196-207. Autor järeldab, et praegu kasutusel olev omavalitsuste finantseerimise süsteem on ammendumas, omavalitsuste tulubaasi probleemi ei lahenda neile isiku tulumaksust senisest suurema osa jätmine. Tabelid

  11. Reason and Culture in Cosmopolitan Education

    Science.gov (United States)

    Waks, Leonard J.

    2009-01-01

    In this essay, Leonard Waks reviews three recent books on cosmopolitan education: Kwame Anthony Appiah's "Cosmopolitanism: Ethics in a World of Strangers"; Neil Burtonwood's "Cultural Diversity, Liberal Pluralism, and Schools: Isaiah Berlin and Education"; and Thomas Popkewitz's "Cosmopolitanism and the Age of School Reform: Science, Education and…

  12. Kinetics and Mechanism of the Oxidation of Coomassie Brilliant Blue ...

    African Journals Online (AJOL)

    NICOLAAS

    Kinetics and Mechanism of the Oxidation of Coomassie Brilliant Blue-R dye by Hypochlorite and Role of Acid there in. Srinivasu Nadupalli, Venkata D.B.C. Dasireddy, Neil A. Koorbanally and Sreekantha B. Jonnalagadda*. School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Private.

  13. Opmaat tot Watergate: Het eerste CIA-schandaal

    NARCIS (Netherlands)

    Vries, Tity de

    2015-01-01

    abstract‘C.I.A. Financed Largest Student Group in U.S.’ kopte de New York Times (nyt) op 14 februari (Valentijnsdag) 1967 op de voorpagina. Verslaggever Neil Sheehan ontketende met dit artikel een reeks van onthullingen over geheime operaties van de Central Intelligence Agency (CIA).

  14. RT 03

    DEFF Research Database (Denmark)

    Alexander, Vera

    2011-01-01

    and our profession as a whole rather than present close readings of specific texts, leaving ample room for discussion. Helga Ramsey Kurz opened the debate with a statement (questions). Greta Olson focussed on the ways in which Neil Forsyth's contribution stressed the historical continuity of terrorism...

  15. Tallinna info- ja abitelefon toetab ka hättasattunud lapsi / Hille Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Hille, 1941-2014

    2006-01-01

    Vt. ka Postimees : na russkom jazõke 16. jaan., lk. 5. Infotelefoni projektijuhi Herve Merivaldi sõnul ei sõanda lapsed lastekaitsetöötaja või politsei poole pöörduda. Abitelefonile helistades aitavad dispetsherid neil ühendust saada inimestega, kes neid aidata võivad

  16. Louis I. Kahn ja Aldo van Eyck : paralleelid moodsa arhitektuuri teises traditsioonis / Robert McCarter ; tõlk. Tiina Randus

    Index Scriptorium Estoniae

    McCarter, Robert

    2007-01-01

    Vaadeldakse Louis I. Kahni ja Aldo van Eycki esinemist 1959. a. CIAMi (Congres Internatinaux d'Architecture Moderne) XI kongressil Otterlos, ajaloolistes paikades saadud kogemuste mõju nende loomingule, suhteid kaasaja kunstnikega ja kunstnike loomingu mõju neile, hoonete kavandamist, linnaarhitektuuri ja -planeerimist. Bibliograafia lk.101-102

  17. Tõusev Hiina / Abdul Turay

    Index Scriptorium Estoniae

    Turay, Abdul, 1967-

    2011-01-01

    Hiina on suur riik suure majandusega ja eestlasedki võiksid sealsele turule minna, kuid Eestis on Idamaad äraunustatud ja Hiinat tundma õppida on raske. Mais teatasid hiinlased, et neil on kavas avada eestikeelne telekanal. Hiina ühiskonna eripäradest. Hiinlaste ja eestlaste sarnasustest ning erinevustest

  18. Research Article ( New England Journal of Medicine ) A trial of a 7 ...

    African Journals Online (AJOL)

    Research Article (New England Journal of Medicine) A trial of a 7-valent pneumococcal conjugate vaccine in HIV-infected adults. Neil French, Stephen B. Gordon, Thandie Mwalukomo, Sarah A. White, Gershom Mwafulirwa, Herbert Longwe, Martin Mwaiponya, Eduard E. Zijlstra, Malcolm E. Molyneux, Charles F. Gilks ...

  19. Idee elluviimisel peab juht saavutama kiiresti veendumuse selle edukuses / Alexander Kotchubei

    Index Scriptorium Estoniae

    Kotchubei, Alexander, 1963-

    2005-01-01

    Ilmunud ka: Juhi ideelaegas. - Tallinn, 2006, lk. 83-85. Ärijuhid leiavad end sageli olukorrast, kus neil tuleb välissurve mõjul tegutseda ilma sisemise veendumuseta, et projekt on õige või õigeaegne. Vt. samas: Projekti kiiret õnnestumist pärsib liigse heakskiidu ootamine teistelt osapooltelt

  20. Astronauts Scott and Armstrong undergoe water egress training

    Science.gov (United States)

    1966-01-01

    Astronauts Neil A. Armstrong (on left), command pilot, and David R. Scott, pilot of the Gemini 8 prime crew, use a boilerplate model of a Gemini spacecraft during water egress training in the Gulf of Mexico. Three Manned Spacecraft Center swimmers assist in the training exercise.

  1. 76 FR 27669 - Automotive Components Holdings, LLC, a Subsidiary of Ford Motor Company, Saline Plant Division...

    Science.gov (United States)

    2011-05-12

    ... Holdings, LLC, a Subsidiary of Ford Motor Company, Saline Plant Division, Including Workers Whose Wages Were Reported Under Ford Company, Visteon, MSX International, W.J. O'Neil Company, and Unibar, Saline... workers of Automotive Components Holdings, LLC, a Subsidiary of Ford Motor Company, Saline Plant Division...

  2. Mr. Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, United Kingdom

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Photos 01,02: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (third from left, front) in front of the ATLAS End-Cap Toroid vacuum vessel in the ATLAS assembly hall with, from left to right, Fred Wickens, Chris Jones, Peter Fletcher, Ray Browne, Neil Geddes, Jim Fleming, Anne Trefethen, Jim Wilson, Edwin Towndrow, Sharon Bonfield, Guy Rickett, Ken Smith, Peter Jenni. Photo 03: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (fifth from left) visiting ATLAS assembly hall with, from left to right, Jim Wilson, Peter Jenni, Ken Smith, Edwin Towndrow, Ray Brown, Chris Jones, Neil Geddes, Sharon Bonfield, Anne Trefethen, Jim Fleming, Fred Wickens. Photo 04: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (fourth from right) in front of the ATLAS Barrel Toroid coil casing in the ATLAS assembly hall with, from left to right, Peter Jenni, Jim Wilson, Guy Rickett, Anne Trefethen, ...

  3. Charge transport problem

    International Nuclear Information System (INIS)

    Lee, E.P.

    1977-01-01

    In a recent report (UCID 17346, ''Relativistic Particle Beam in a Semi-Infinite Axially Symmetric conducting channel extending from a perfectly conducting plane,'' Dec. 13, 1976) Cooper and Neil demonstrate that the net charge transported by a beam pulse injected into a channel of finite conductivity equals the charge of the beam itself. The channel is taken to be infinite in the positive z direction, has finite radius and is terminated by a conducting ground plane at z =0. This result is not an obvious one, and it is restricted in its applicability by the special model assumed for the channel. It is the purpose to explain the result of Cooper and Neil in more qualitative terms and to make similar calculations using several other channel models. It must be emphasized that these calculations are not concerned with the fate of the transported charge after the pulse has stopped, but rather with how much charge leaves the ground plane assuming the pulse does not stop

  4. The universe within from quantum to cosmos

    CERN Document Server

    Turok, Neil

    2012-01-01

    A visionary look at the way the human mind can shape the future by world-renowned physicist Neil Turok. Every technology we rely on today was created by the human mind, seeking to understand the universe around us. Scientific knowledge is our most precious possession, and our future will be shaped by the breakthroughs to come. In this personal and fascinating work, Neil Turok, Director of the Perimeter Institute for Theoretical Physics, explores the transformative scientific discoveries of the past three centuries -- from classical mechanics, to the nature of light, to the bizarre world of the quantum, and the evolution of the cosmos. Each new discovery has, over time, yielded new technologies causing paradigm shifts in the organization of society. Now, he argues, we are on the cusp of another major transformation: the coming quantum revolution that will supplant our current, dissatisfying digital age. Facing this brave new world, Turok calls for creatively re-inventing the way advanced knowledge is developed...

  5. Self-consistent Langmuir waves in resonantly driven thermal plasmas

    Science.gov (United States)

    Lindberg, R. R.; Charman, A. E.; Wurtele, J. S.

    2007-12-01

    The longitudinal dynamics of a resonantly driven Langmuir wave are analyzed in the limit that the growth of the electrostatic wave is slow compared to the bounce frequency. Using simple physical arguments, the nonlinear distribution function is shown to be nearly invariant in the canonical particle action, provided both a spatially uniform term and higher-order spatial harmonics are included along with the fundamental in the longitudinal electric field. Requirements of self-consistency with the electrostatic potential yield the basic properties of the nonlinear distribution function, including a frequency shift that agrees closely with driven, electrostatic particle simulations over a range of temperatures. This extends earlier work on nonlinear Langmuir waves by Morales and O'Neil [G. J. Morales and T. M. O'Neil, Phys. Rev. Lett. 28, 417 (1972)] and Dewar [R. L. Dewar, Phys. Plasmas 15, 712 (1972)], and could form the basis of a reduced kinetic treatment of plasma dynamics for accelerator applications or Raman backscatter.

  6. Self-consistent Langmuir waves in resonantly driven thermal plasmas

    International Nuclear Information System (INIS)

    Lindberg, R. R.; Charman, A. E.; Wurtele, J. S.

    2007-01-01

    The longitudinal dynamics of a resonantly driven Langmuir wave are analyzed in the limit that the growth of the electrostatic wave is slow compared to the bounce frequency. Using simple physical arguments, the nonlinear distribution function is shown to be nearly invariant in the canonical particle action, provided both a spatially uniform term and higher-order spatial harmonics are included along with the fundamental in the longitudinal electric field. Requirements of self-consistency with the electrostatic potential yield the basic properties of the nonlinear distribution function, including a frequency shift that agrees closely with driven, electrostatic particle simulations over a range of temperatures. This extends earlier work on nonlinear Langmuir waves by Morales and O'Neil [G. J. Morales and T. M. O'Neil, Phys. Rev. Lett. 28, 417 (1972)] and Dewar [R. L. Dewar, Phys. Plasmas 15, 712 (1972)], and could form the basis of a reduced kinetic treatment of plasma dynamics for accelerator applications or Raman backscatter

  7. Author Details

    African Journals Online (AJOL)

    Soderlund, Neil. Vol 92, No 5 (2002) - Articles Patterns and determinants of acute psychiatric readmissions. Abstract PDF · Vol 89, No 7 (1999) - Articles An essential hospital package for South Africa selection criteria, costs and affordability. Abstract PDF. ISSN: 0256-95749. AJOL African Journals Online. HOW TO USE ...

  8. Sõnavabaduse dogma Hollandi moodi / Kaspar Näf

    Index Scriptorium Estoniae

    Näf, Kaspar

    2008-01-01

    Šveitsi ajaloolane ja ajakirjanik leiab Hollandi parlamendisaadiku Geert Wildersi islami-vastase filmi ja ENPA endise presidendi Rene van der Lindeni arvamusavaldustega seoses, et kui sõnavabadus ja arvamuse väljendamine on eesmärk iseenesest, siis on see eriti neil juhtudel absurdne, kui seab teisi inimesi ohtu

  9. Habent sua fata motae picturae / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2008-01-01

    1968. aastal Eesti Telefilmis valminud 3-osaline mängufilm "Pimedad aknad" Lilli Prometi jutustuse "Pimedate akende aegu" järgi (režissöör Tõnis Kask) restaureeriti ja helindati uuesti (restaureerisid ETV ja OÜ Profilm). Lisatud "1965-1974: Eesti televisioon õitseb" - olulist ETVs neil aastail

  10. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (86th, Kansas City, Missouri, July 30-August 2, 2003). Media Ethics Division.

    Science.gov (United States)

    2003

    The Media Ethics Division of the proceedings contains the following 10 papers: "Punctuation and Epistemic Honesty: Do Photos Need What Words Have?" (Scott Fosdick and Shahira Fahmy); "A Bellwether in Media Accountability: The Work of the New York 'World's' Bureau of Accuracy and Fair Play" (Neil Nemeth); "Eight Arguments…

  11. Maksuparadiisid peidavad 9 triljonit dollarit / Erik Aru

    Index Scriptorium Estoniae

    Aru, Erik

    2011-01-01

    Sajal suuremal Londoni börsifirmal on umbes 8500 offshore-tütarfirmat. Global Financial Integrity hinnangul kaotavad vaesed riigid igal aastal maksuparadiisidesse üle triljoni dollari eest tulu, seda on üle 10 korra rohkem neile antavast arenguabist, teistel hinnangutel on maksuparadiisidesse peidetud kokku 9 triljonit dollarit

  12. Karunahk ja Berlinale kroonijuveel / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2006-01-01

    56. Berliini filmifestivali filmide auhindamisest- Kuldkaru saanud Jasmila Zhbavici "Grbavica", režii Hõbekaru saajad britid Michael Winterbottom ja Mat Whitecross filmi eest "Teekond Guatanamosse" ("The Road to Guantanamo"). Autori lemmik oli aga Panorama kavas olnud Neil Jordani "Hommikusöök Pluutol". Lisatud nimekiri "56. Berlinale peaauhinnad"

  13. Muusikauudiseid maailmast / Nele-Eva Steinfeld

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2015-01-01

    Lühisõnumeid maailmast: Londonis kuulutati välja aasta ooperiauhinnad. Philip Glass pälvis Glenn Gouldi preemia. Neil Shicoff asub juhtima Mihhailovski teatrit. Metsosopran Tuuri Tede edu Sibeliuse konkursil. Risto Joost Malko konkursil neljas. Julia Wolfe pälvis Pulitzeri preemia. Bachi kuulus portree jõudis Leipzigisse

  14. Plaadisoovitus

    Index Scriptorium Estoniae

    2006-01-01

    Uutest heliplaatidest dieter Bohlen "Dieter", Neil Young "Living With War", "Hip Hop IV", Chris Isaak "Best Of", Tom Jones "Graetest Hits", juanes "Mi Sangre", The Poison "Bullet For My Valentine", "Metal For Masses", Pet Shop Boys "Fundamental", Prince "3121", gnarls Barkley "St Elsewhere" Hoobastank "Every Man For Himself"

  15. 76 FR 58277 - Performance Review Board Members

    Science.gov (United States)

    2011-09-20

    .... Cantrell, Patrick H. Conway, Kathleen M. Crosby, John Czajkowski, Cheryl R. Dammons, Michelle S. Davis..., William B. Schultz, Neil Shapiro, Jeremy B. Sharp, George H. Sheldon, Steven D. Silverman, Rebecca T... E. Tyler Jr., Stephen J. Veneruso, Karen V. Walker Bryce, Luis A. Wilmot, Holly J. Wong, Robert K...

  16. Scalable Beaconing for Cooperative Adaptive Cruise Control

    NARCIS (Netherlands)

    van Eenennaam, Martijn

    2013-01-01

    Over the past two hundred years, automotive technology has evolved from mechanised horse carriage to high-tech systems which pack more computing power than the entire space program that put Neil Armstrong on the moon. Hand-in-hand with this evolution came a proliferation of ownership and use of

  17. Katrina ohvrite mälestuspäev / Aldona Zofia Wos

    Index Scriptorium Estoniae

    Wos, Aldona Zofia

    2005-01-01

    Ameerika Eesti suursaadiku soov on, et eestimaalased leiaksid 16. septembril - Katrina ohvrite mälestuspäeval - aega ja mõtleksid neile, kes kaotasid orkaani laastamistöö tulemusel oma elu. USA valitsuse abist pääste- ja taastamistööde läbiviimisele katastroofi piirkonnas

  18. 75 FR 48352 - Determination That MOTRIN (Ibuprofen) Tablets and Four Other Drug Products Were Not Withdrawn...

    Science.gov (United States)

    2010-08-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0391] Determination That MOTRIN (Ibuprofen) Tablets and Four Other Drug Products Were Not Withdrawn From Sale for... Applicant NDA 17-463 MOTRIN (ibuprofen) Tablets, 300 milligrams (mg), McNeil Consumer Healthcare, 7050 Camp...

  19. Ikka mõtlen neile, kes siit viidi... / Ralf R. Parve

    Index Scriptorium Estoniae

    Parve, Ralf R., 1946-2008

    2007-01-01

    1941. aasta juuniküüditamisest, esimesest küüditamise mälestuspäevast 1942. aastal. Küüditatutele püstitatud mälestusmärkidest Eestis. Sisaldab Eesti elanike Venemaale küüditamise kronoloogiat alates 1558. aastast: "Juuniküüditamine oli ahela üks lüli"

  20. Comprehensive profiling of DNA repair defects in breast cancer identifies a novel class of endocrine therapy resistance drivers.

    Science.gov (United States)

    Anurag, Meenakshi; Punturi, Nindo; Hoog, Jeremy; Bainbridge, Matthew N; Ellis, Matthew J; Haricharan, Svasti

    2018-05-23

    This study was undertaken to conduct a comprehensive investigation of the role of DNA damage repair (DDR) defects in poor outcome ER+ disease. Expression and mutational status of DDR genes in ER+ breast tumors were correlated with proliferative response in neoadjuvant aromatase inhibitor therapy trials (discovery data set), with outcomes in METABRIC, TCGA and Loi data sets (validation data sets), and in patient derived xenografts. A causal relationship between candidate DDR genes and endocrine treatment response, and the underlying mechanism, was then tested in ER+ breast cancer cell lines. Correlations between loss of expression of three genes: CETN2 (p<0.001) and ERCC1 (p=0.01) from the nucleotide excision repair (NER) and NEIL2 (p=0.04) from the base excision repair (BER) pathways were associated with endocrine treatment resistance in discovery data sets, and subsequently validated in independent patient cohorts. Complementary mutation analysis supported associations between mutations in NER and BER pathways and reduced endocrine treatment response. A causal role for CETN2, NEIL2 and ERCC1 loss in intrinsic endocrine resistance was experimentally validated in ER+ breast cancer cell lines, and in ER+ patient-derived xenograft models. Loss of CETN2, NEIL2 or ERCC1 induced endocrine treatment response by dysregulating G1/S transition, and therefore, increased sensitivity to CDK4/6 inhibitors. A combined DDR signature score was developed that predicted poor outcome in multiple patient cohorts. This report identifies DDR defects as a new class of endocrine treatment resistance drivers and indicates new avenues for predicting efficacy of CDK4/6 inhibition in the adjuvant treatment setting. Copyright ©2018, American Association for Cancer Research.

  1. Browse Title Index

    African Journals Online (AJOL)

    Items 101 - 108 of 108 ... Issue, Title. Vol 8, No 2 (2016), The status and challenges of clinical informatics development in South Africa, Abstract PDF. Abayomi Kehinde Owolabi, Thokozani Patrick Mhlongo, Neil Evans. Vol 4, No 1 (2012), The stuttering implementation of language policies in the South African education system ...

  2. Symposium on the Nature of Science—Streaming Video Archive

    Science.gov (United States)

    Oddone – Welcome Mark Ratner – Nano 201: A Gentle Introduction to Nanotechnology and Nanoscience Marsha Physical Sciences Neil Kelleher – How a Chemist Needs Computer Science, Biology, and Engineering to Push – Incorporating Nanotechnology into the Curriculum (streamed session not available) Rich Marvin – Using

  3. ISISe kadudes jätkaks võitlejad rünnakuid oma päritolumaades / Gil Ad Ariely ; intervjueerinud Taavi Minnik

    Index Scriptorium Estoniae

    Ariely, Gil Ad

    2016-01-01

    Intervjuu Iisraeli riikliku julgeoleku-uuringute instituudi vanemteaduri ja Iisraeli armee erukolonelleitnandi Gil Ad Arielyga. Islamiriigi survestamine Süürias ja Iraagis võib kaasa tuua õhupalliefekti - enamik välisvõitlejaid läheks sinna, kus neil on mugavam ja kus on võimalik oma võitlust jätkata

  4. Children and Chess: A Guide for Educators

    Science.gov (United States)

    Root, Alexey

    2006-01-01

    "Children and Chess: A Guide for Educators" is the first book to show the connection between accepted educational theories and chess. The relationship of chess to academic and humanistic educational goals is convincingly illustrated as curriculum and psychological theories from John D. McNeil, Mihaly Csikszentmihalyi, and Howard Gardner are…

  5. There's more to the picture than meets the eye

    DEFF Research Database (Denmark)

    Svendsen, Gunnar Lind Haase; Sørensen, Jens Fyhn Lykke

    2007-01-01

    observation, most economists have failed to see that ‘there's more to the picture than meets the eye', as Neil Young once sang. We use statistical, historical and fieldwork data from two Danish, marginal rural communities both rich on intangible capital. This to show how intangible capital in the form...

  6. Nationalism, Mass Politics, and Sport: Cold War Case Studies at Seven Degrees

    Science.gov (United States)

    2008-06-01

    recognized state.”34 Patrick O’Neil maintains nationalism is “a pride in one’s people and the belief that they have their own sovereign political destiny ...because of nationalist movements and the peoples’ desires for self-rule. Colonialism provided the embryo in which the nation- state would gestate.57

  7. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... for third-order aberration in the reconstructed wave front of point objects are established by Meier. But Smith, Neil Mohon, Sweatt independently reported that their results differ from that of Meier. We found that coefficients for spherical aberration, astigmatism, tally with Meier's while coefficients for distortion and coma differ.

  8. Saastunud kurke Eestis ei müüda / Dannar Leitmaa

    Index Scriptorium Estoniae

    Leitmaa, Dannar, 1982-

    2011-01-01

    Hispaaniast või Hollandist pärit kolibakteriga mürgitunud kurgid on Saksamaal juba viienda ohvri nõudnud. Nakatunuid on ligi 200, kuid võib olla rohkemgi. Eesti kauplused kinnitavad, et neile pole selliste kurkide päritolupiirkonnast köögivilju toodud. Sagro tootmisjuht Madis Kahu kurgikasvatusest Eestis

  9. Võbora net? / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2007-01-01

    Autor kaalutleb parteide võimaluste üle Riigikogu valimistel ning leiab, et Isamaaliidu ja Res Publica ühinemine vaevalt neile valijaid oluliselt juurde toob, pealegi kandideerib Mart Laar Riigikogu valimistel valimisringkonnas, kus enamik valijaist elab Lasnamäel. Reformierakond on seoses pronkssõduriga kaotanud vene valijate hääli

  10. New directions in climate change vulnerability, impacts, and adaptation assessment: summary of a workshop

    National Research Council Canada - National Science Library

    National Research Council (U.S.). Subcommittee for a Workshop on New Directions in Vulnerability, Impacts, and Adaptation Assessment; National Academies Press (U.S.); National Research Council (U.S.). Division of Behavioral and Social Sciences and Education; National Research Council (U.S.). Committee on the Human Dimensions of Global Change; Brewer, Jennifer F

    ... special thanks for providing the original idea, motivation, and organizational efforts. Our work also benefited significantly from the thoughtful contributions of Gary Yohe and Linda Mearns. In addition to the members of the subcommittee, the other workshop presenters, Neil Leary, Richard Moss, Martin Parry, and Roger Pulwarty, helped greatly in orie...

  11. 75 FR 44049 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-07-27

    .... Koegel, Nicholas J. Niemerg, Dereck J. Oliveira, Paul J. O'Neil, Jr., Worden T. Price, Frankie R. Ramey... the twenty-five exemption applications, FMCSA exempts, Calvin R. Adams, Michael R. Amstutz, Clinton R. Carlson, II, Brandon L. Cheek, Michael J. Drake, Richard A. Dufton, Jr., Kenneth Dunn, Robert J. Dyxin...

  12. Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri

    2003-01-01

    Concordia Ülikooli rektori kohast loobunud Mart Susi ning prorektori ametikohalt lahkunud Mari-Ann Susi taotlevad neile kuuluvat ülikooli pidanud miljonivõlgades firma pankrotti. Hiljuti loodi õppejõududest, tudengitest js töötajatest mittetulundusühing Concordia Akadeemiline Ühisus (CAU), selle nõukogu esimees on Hagi Šein

  13. Island otsib sõjalisi kaitseingleid / Allan Espenberg

    Index Scriptorium Estoniae

    Espenberg, Allan

    2007-01-01

    Islandil toimuvatel parlamendivalimistel peaks arvamusküsitluste kohaselt enam kui 40% valijatest toetama Iseseisvusparteid, teisele kohale jäävad sotsiaaldemokraadid 23,5% ning neile järgnevad rohelised 17,6 ja Progressiivne Partei 10%-ga. Ka Islandi-Norra kahepoolsest lepingust, mis tihendab kaitse- ja julgeolekualast koostööd

  14. Toimetulekust tõrjutuna ühiskonna äärealale / Dagmar Kutsar

    Index Scriptorium Estoniae

    Kutsar, Dagmar, 1951-

    2006-01-01

    Sotsiaalse tõrjutuse üks liike on tõrjutus võimu ja mõju mehhanismidest ehk jäämine kultuurilises mõttes ühiskonna äärealadele. Graafik: Vastanud, kes leidsid, et neil ei ole lähedast inimest, kellega arutada isiklikke ja intiimseid asju, tuludetsiili järgi, %

  15. When Social Identities Collide: Commentary on "Gender in the Management Education Classroom"

    Science.gov (United States)

    Patton, Eric

    2010-01-01

    This commentary to "Gender in the Management Education Classroom" (Bilimoria, O'Neil, Hopkins, & Murphy, 2010) employs social identity and self-categorization theory to analyze the incident described in the article. In any MBA classroom, students are dealing with multiple group memberships. Similar to workplace settings, when the focus is on…

  16. Armstrong practices in Lunar Module simulator

    Science.gov (United States)

    1969-01-01

    Neil A. Armstrong, Commander for the Apollo 11 Moon-landing mission, practices for the historic event in a Lunar Module simulator in the Flight Crew Training building at KSC. Accompanying Armstrong on the Moon flight will be Command Module Pilot Michael Collins and Lunar Module Pilot Edwin E. Aldrin Jr.

  17. Prince Rabbiteye Blueberry

    Science.gov (United States)

    'Prince' is a new early ripening rabbiteye blueberry released by the U.S. Depaertment of Agriculture's Agricultural Research Service. Prince was selected from a cross of MS 598 and FL 80-11 in 1996, and tested in field plantings at McNeil and Stone County, MS beginning in 2000. Prince flowers and...

  18. Maanoorte elu pole üldsegi nukker / Marit Kannelmäe

    Index Scriptorium Estoniae

    Kannelmäe, Marit

    2008-01-01

    Utrechti Ülikoolis kaitstud magistritööst: "Youth Participation in Rural Areas of Estonia - Equal Opportunities for Rural Youth", millest selgus, et noored, kellele on antud võimalus olla aktiivne ja ennast proovile panna, tunnevad, et nende arvamus läheb korda ning neil on endil üha rohkem algatusvõimet

  19. Brain Drain: A Child's Brain on Poverty. Poverty Fact Sheet

    Science.gov (United States)

    Damron, Neil

    2015-01-01

    "Brain Drain: A Child's Brain on Poverty," released in March 2015 and prepared by intern Neil Damron, explores the brain's basic anatomy and recent research findings suggesting that poverty affects the brain development of infants and young children and the potential lifelong effects of the changes. The sheet draws from a variety of…

  20. OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study

    DEFF Research Database (Denmark)

    Hatt, Lotte; Loft, Steffen; Risom, Lotte

    2008-01-01

    Oxidative DNA damage is believed to be implicated in lung carcinogenesis. 8-OxodG is a mutagenic and abundant oxidative modification induced in DNA. OGG1, NEIL1 and MUTYH are all involved in the repair and prevention of 8-oxodG-derived mutations and may be up-regulated by oxidative stress...

  1. Welcoming a New Generation to College: The Millennial Students

    Science.gov (United States)

    Elam, Carol; Stratton, Terry; Gibson, Denise D.

    2007-01-01

    High on any required reading list for college-level student affairs officers and high school counselors is "Millennials Rising: The Next Great Generation" by Neil Howe and William Strauss (2000). Experts on generational change in the United States, the authors contend that the current generation of college-age and pre-college-age…

  2. Plaadid / Ants Tõnisson

    Index Scriptorium Estoniae

    Tõnisson, Ants

    2004-01-01

    Uutest heliplaatidest Neil Young "Greatest Hits", The Jacksons "The Very Best Of", Seal "Best 1991-2004", Tina Turner "All The Best", "Bridget Jones", Gotan Project "Inspiracio", Xzibit "Weapons Of Mass", Annie "Anniemal", Terry Callier "Lookin' Out", Lamb Of God "Ashes Of The Wake", Robbie Williams "Greatest Hits", "Jazz In The House", "Earth"

  3. Sõtke külas hakatakse kuduma plastist kotikangast / Gerli Romanovitsh

    Index Scriptorium Estoniae

    Romanovitš, Gerli, 1977-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 4. märts lk. 4. Sõtke külas endisest sigalast tootmiseks ümber kohandatud hoonet rentiv Alekor Textile hakkab tootma polüpropüleenkangast, kui tööhõiveameti abiga on leidnud vajalikud 30 töötajat ning andnud neile väljaõppe

  4. Reliability and Validity of the Computerized Revised Token Test: Comparison of Reading and Listening Versions in Persons with and without Aphasia

    Science.gov (United States)

    McNeil, Malcolm R.; Pratt, Sheila R.; Szuminsky, Neil; Sung, Jee Eun; Fossett, Tepanta R. D.; Fassbinder, Wiltrud; Lim, Kyoung Yuel

    2015-01-01

    Purpose: This study assessed the reliability and validity of intermodality associations and differences in persons with aphasia (PWA) and healthy controls (HC) on a computerized listening and 3 reading versions of the Revised Token Test (RTT; McNeil & Prescott, 1978). Method: Thirty PWA and 30 HC completed the test versions, including a…

  5. Fatal Amusements: Contemplating the Tempest of Contemporary Media and American Culture

    Science.gov (United States)

    Strate, Lance

    2016-01-01

    Our use of the electronic media to conduct serious discourse raises the question of whether "we are amusing ourselves to death," as Neil Postman argued. The approach known as "media ecology," the study of media as environments, which emphasizes the need to understand context and find balance, provides a basis for the analysis…

  6. 77 FR 32116 - Findings of Research Misconduct

    Science.gov (United States)

    2012-05-31

    ..., R. Thomas, D. Neil Hayes, M. Meyerson, D.J. Kwiatkowski, and K.-K. Wong, submitted to the Journal of... supervisory plan must be designed to ensure the scientific integrity of his research contribution; Respondent... application for PHS funds or any report, manuscript, or abstract of PHS-funded research in which he is...

  7. Astronaut Aldrin is photographed by Astronaut Armstrong on the Moon

    Science.gov (United States)

    1969-01-01

    Apollo 11 Onboard Film -- The deployment of scientific experiments by Astronaut Edwin Aldrin Jr. is photographed by Astronaut Neil Armstrong. Man's first landing on the Moon occurred today at 4:17 p.m. as Lunar Module 'Eagle' touched down gently on the Sea of Tranquility on the east side of the Moon.

  8. Radiation hard silicon microstrip detectors for Tevatron experiments

    International Nuclear Information System (INIS)

    Korjenevski, Sergey

    2004-01-01

    The Silicon Microstrip Tracking detectors at the CDF and D0 experiments have now been operating for almost three years at Fermilab. These detectors were designed originally for an integrated luminosity of 2fb -1 . As the expected luminosity for Run IIb at the Tevatron collider was initially envisioned to reach 15fb -1 , radiation tolerances of both devices were revisited, culminating in proposals for new systems. With reduced expectations for total luminosity at ∼6fb -1 , the full detector-replacement projects were terminated. The CDF detector is expected nevertheless to cope efficiently with the lower anticipated dose, however, the D0 experiment is planning a smaller-scale project: a Layer-0 (L0) upgrade of the silicon tracker (D0SMT). The new device will fit between the beam line and the inner layer of the current Tracker. Built of single-sided sensors, this upgrade is expected to perform well in the harsh radiation environment, and be able to withstand an integrated luminosity of 15fb -1 . Prototypes of Run IIb sensors were irradiated using 10MeV protons at the tandem Van de Graaff at the James R. McDonald Laboratory at Kansas State University. A fit to the 10MeV proton data yields a damage parameter αp=11x10-17Acm. This is consistent with results from RD48 (αp=9.9x10-17Acm). The scaling of damage to 1MeV neutron fluence uses a hardness factor (κ) derived from the non-ionizing components of the energy loss (NEIL). NEIL predicts a hardness factor of 3.87 for 10MeV protons. We obtained an experimental value of this factor of 2.54, or 34% smaller than scaling predictions from NEIL

  9. A Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These "Spare Tires" Have an Evolved Function?

    Science.gov (United States)

    Fleming, Aaron M; Zhou, Jia; Wallace, Susan S; Burrows, Cynthia J

    2015-08-26

    Uncontrolled inflammation or oxidative stress generates electron-deficient species that oxidize the genome increasing its instability in cancer. The G-quadruplex (G4) sequences regulating the c-MYC , KRAS , VEGF , BCL-2 , HIF-1α , and RET oncogenes, as examples, are targets for oxidation at loop and 5'-core guanines (G) as showcased in this study by CO 3 •- oxidation of the VEGF G4. Products observed include 8-oxo-7,8-dihydroguanine (OG), spiroiminodihydantoin (Sp), and 5-guanidinohydantoin (Gh). Our previous studies found that OG and Gh, when present in the four G-tracks of the solved structure for VEGF and c-MY C, were not substrates for the base excision repair (BER) DNA glycosylases in biologically relevant KCl solutions. We now hypothesize that a fifth G-track found a few nucleotides distant from the G4 tracks involved in folding can act as a "spare tire," facilitating extrusion of a damaged G-run into a large loop that then becomes a substrate for BER. Thermodynamic, spectroscopic, and DMS footprinting studies verified the fifth domain replacing a damaged G-track with OG or Gh at a loop or core position in the VEGF G4. These new "spare tire"-containing strands with Gh in loops are now found to be substrates for initiation of BER with the NEIL1, NEIL2, and NEIL3 DNA glycosylases. The results support a hypothesis in which regulatory G4s carry a "spare-tire" fifth G-track for aiding in the repair process when these sequences are damaged by radical oxygen species, a feature observed in a large number of these sequences. Furthermore, formation and repair of oxidized bases in promoter regions may constitute an additional example of epigenetic modification, in this case of guanine bases, to regulate gene expression in which the G4 sequences act as sensors of oxidative stress.

  10. Kes on kes ehk Tulgu uus taevas / Ervin Õunapuu

    Index Scriptorium Estoniae

    Õunapuu, Ervin, 1956-

    2002-01-01

    Tuntud tegijad, kes on oma sõnul ateistid, agnostikud või umbuskliku suhtumisega ristiusu kirikusse: William Seward Burroughs, Vincent Van Gogh, Oscar Niemeyer, Sven Alur Reinans, Sir Joshua Reynolds, Diego Rivera, Neil Rogers, John Ruskin, Matt Wagner, Frank Lloyd Wright, Ervin Õunapuu jne. Ilmunud ka kogumikus "Öövöö", lk.109-124

  11. pulmonary candidiasis and cd4 count

    African Journals Online (AJOL)

    boaz

    Assessment of Clinical case-definition for. HIV/AIDS in Tanzania. East Afr Med J. 2004; 81(5): 226-9. 14. Neil M A. Emerging Diseases Issues and. Fungal Pathogens Associated with HIV. Infection. Emerg Infect Dis. 1995; 2 (20):. 520-29. 15. Neoza Dlova and Anisa Mosam. Cutaneous Manifestations of HIV/AIDS: Part 1.

  12. No Place to Call Home: Child & Youth Homelessness in the United States. Poverty Fact Sheet

    Science.gov (United States)

    Damron, Neil

    2015-01-01

    "No Place to Call Home: Child and Youth Homelessness in the United States," prepared by intern Neil Damron and released in May 2015, presents the statistics on child and youth homelessness and recent trends in Wisconsin and the United States. It explores the major challenges faced by homeless minors, and, drawing from recent research by…

  13. The Next Great Generation?

    Science.gov (United States)

    Brownstein, Andrew

    2000-01-01

    Discusses ideas from a new book, "Millennials Rising: The Next Great Generation," (by Neil Howe and William Strauss) suggesting that youth culture is on the cusp of a radical shift with the generation beginning with this year's college freshmen who are typically team oriented, optimistic, and poised for greatness on a global scale. Includes a…

  14. Thinking Complexly about Men, Gender Role Conflict, and Counseling Psychology

    Science.gov (United States)

    Wester, Stephen R.

    2008-01-01

    O'Neil (2008) defines male gender role conflict (GRC) as a psychological state in which the socialized male gender role has negative consequences for the person or others. Building on this, many now realize that the mechanisms through which these negative consequences occur, rather than being global, are instead contextual. That is, different men…

  15. Tõlkeküsimused

    Index Scriptorium Estoniae

    2005-01-01

    Tõlkimine ja tõlgendamine, õigussüsteemide erisused, udutamine, moodultõlge, metafoorse tähendusülekandega terminite tõlkimine, Euroopa Kohtus kasutatavaid termineid, Euroopa Liidu õigusaktide jaotuselemendid ja neile viitamine. - Kokkuvõte Hille Saluääre, Kristiina Rossi, Mari Suti, Heljo Kontsa, Helve Hennoste, Aime Vettiku, Madis Vunderi ja Ülle Raigi artiklitest

  16. Eesti kaubavahetus majanduse põhikategooriate järgi = Foreign trade of Estonia by broad economic categories / Riina Kerner, Allan Aron

    Index Scriptorium Estoniae

    Kerner, Riina

    2010-01-01

    Eesti väliskaubanduse näitajatest 2009. aastal: Eesti kaupade eksport oli 101,3 miljardit krooni, import 114,1 miljardit krooni, kaubavahetuse puudujääk oli 12,8 miljardit krooni. Majanduse põhikategooriate järgi oli suurim osatähtsus kaubavahetuses vahetarbekaupadel, neile järgnesid tarbekaubad ja kapitalikaubad. Diagramm. Graafikud

  17. Miks IMF ei kiirusta riike rahanduskriisist päästma? / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2008-01-01

    Mitu riiki taotleb IMF-ilt kriisiabi, IMF esitab neile abi andmiseks rangeid nõudeid. Varasemates kriisides on IMF-i rahast piisanud, kuid suuremaid tööstusriike ta välja aidata ei suudaks, selle juhi Dominique Strauss-Kahni prognoosi kohaselt peab IMF seekord välja andma sadu miljardeid dollareid. Lisa: Pangajuhti tabas seksiskandaal

  18. Iisraeli-Palestiina vastasseis : kahe tõe võitlus määrib mõlemad verega / Ivar Soopan

    Index Scriptorium Estoniae

    Soopan, Ivar, 1971-

    2007-01-01

    Iisraeli-Palestiina konflikt alates 1967. aastast. Vt. samas: Minister kurdab apartheidi. Palestiina teabeminister Mustafa Barghouti ütles intervjuus ajalehele Palestine Times, et vastasseis Iisraeliga laheneks, kui Iisrael tunnistaks, et palestiinlased ja iisraellased on võrdsed inimesed võrdsete õigustega ja neil peaksid olema võrdsed võimalused. Tema sõnul on okupatsioon loonud Palestiinas apartheidi

  19. Tsherez 30 let Jevropu zahvatjat "varvarõ" / Mihhail Ozerov

    Index Scriptorium Estoniae

    Ozerov, Mihhail

    2006-01-01

    Briti kontradmiral Chris Parry hoiatab oma ettekandes, et lähema 30 aasta jooksul hõivavad Euroopa immigrandid Kolmandast Maailmast, neil ei midagi ühist Euroopaga, veelgi enam - nad vihkavad seda. Intervjuu Briti parlamendiliikme Boris Johnsoniga. Postindustriaalse ühiskonna uurimise keskuse teaduslik juht Vladislav Inozemtsev on seisukohal, et immigrandid Venemaa julgeolekut ei ohusta. Tabel

  20. Plaadid / Priit Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Priit, 1957-

    2006-01-01

    Uutest heliplaatidest "Wolfmother", Futureheads "News and Tributes", Sonic Youth "Rather Ripped", tanel Padar & The Sun "100% rock'n'roll", The Raconteurs "Broken toy Soldiers", neil Young "Living With War", Moloko "Catalogue", Nelly Furtado "Loose", Busta Rhymes "Big Bang", "R2 Live. Vol 1", Tiesto "In Search Of Sunrise", "Moon Taxi", Zero 7 "The Garden"

  1. TRT and SCT barrels merge

    CERN Multimedia

    Wells, P S

    2006-01-01

    The SCT barrel was inserted in the TRT on 17 February, just missing Valentine's day. This was a change of emphasis for the two detectors. In the preceeding months there had been a lot of focus on testing their performance. The TRT had been observing cosmic rays through several sectors of the barrel, and all the modules on each of the four layers of the SCT had been characterised prior to integration. In parallel, the engineering teams, lead by Marco Olcese, Andrea Catinaccio, Eric Perrin, Neil Dixon, Iourii Gusakov, Gerard Barbier and Takashi Kohriki, had been preparing for this critical operation. Figure 1: Neil Dixon and Marco Olcese verifying the final alignment The two detectors had to be painstakingly aligned to be concentric to within a millimetre. The SCT was held on a temporary cantilever stand, and the TRT in the ID trolley had to inch over it. Finally the weight of the SCT was transferred to the rails on the inside of the TRT itself. The SCT services actually protruded a little outside the oute...

  2. Apollo 11 Astronaut Armstrong Arrives at the Flight Crew Training Building

    Science.gov (United States)

    1969-01-01

    In this photograph, Apollo 11 astronaut Neil Armstrong walks to the flight crew training building at the NASA Kennedy Space Center (KSC) in Florida, one week before the nation's first lunar landing mission. The Apollo 11 mission launched from KSC via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  3. Disaster Planning Guidelines for Fire Chiefs.

    Science.gov (United States)

    1980-07-01

    book Money Receipts e I pad white squared paper * I roll masking tape (8 X 13) (-" × 60yds) * 3 spring clips * 3 felt tip markers (red, e I pkg. freezer...Avenue COMMIT EE HaRm Washington. D.C. 20012 C.Holy Redeemer Rectory (202) 723-0800 C. Neil Molenaar 9705 Summit Avenue Director, Domestic Programs

  4. Esmatähtis on rahva heaolu / Mai Treial

    Index Scriptorium Estoniae

    Treial, Mai, 1952-

    2003-01-01

    Ilmunud ka: Meie Maa 7. jaan. lk. 2, Molodjozh Estonii 4. jaanuar lk. 4, Valgamaalane 9. jaanuar lk. 2 "Inimene väärib paremat", Põhjarannik, Severnoje Poberezhje 10. jaanuar lk. 2 "Riik peab senisest rohkem toetama abivajajaid", Vooremaa 18. jaanuar lk. 5. Sotsiaalabi kaudu peab riik tagama piisavalt vahendeid neile, kes ise hakkama ei saa. Sotsiaalhoolekande seadusest

  5. Between Russia and Estonia: narratives of place in a new borderland / Alena Pfoser

    Index Scriptorium Estoniae

    Pfoser, Alena

    2014-01-01

    Artikkel käsitleb Eesti ja Venemaa piiri läheduses elavaid inimesi – kuidas nad mõtestavad kohta, kus nad elavad, kuidas nad tajuvad viimastel kümnenditel aset leidnud muutusi, millist mõju avaldab neile nõukogulik minevik jne. Aluseks Narvas ja Ivangorodis teostatud etnograafilised välitööd aastatel 2011-2012

  6. Urea/thiourea derivatives and Zn(II)-DPA complex as receptors for ...

    Indian Academy of Sciences (India)

    of industries related to agricultural fertilizers, food additives and water. Along with these, recent emphasis on environmental concern — both industrially and ...... Tocci G M, Kruger P E and Pfeffer F M 2006 Coord. Chem. Rev. 250 3094; (p) Filby M H and Steed J W 2006. Coord. Chem. Rev. 250 3200; (q) O'Neil E J and ...

  7. Optimized Breech Location in the Harry Diamond Laboratories 4-Inch Gas Gun

    Science.gov (United States)

    1982-04-01

    equation can be deduced from the program, it is camouflaged by changes in notation and is repeated here. PAY/ Ma2 = [u-N/(N +1)](1 —u/N)1 + N/(N + 1...AERO-ASTRONAUTICAL ENGINEERING ATTN PROF TING YI LI 2036 NEIL AVENUE COLUMBUS, OH 43210 OCEANICS, INC ATTN DR. PAUL KAPLAN PLAINVIEW LONG ISLAND

  8. Tropical Veterinarian - Vol 24, No 1-2 (2006)

    African Journals Online (AJOL)

    Effectiveness of levamisole® in the treatment of natural multiple helminth infection of ruminants in Zaria: A case report. EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J S Neils, J P Nzalak, J B George, 23-31. http://dx.doi.org/10.4314/tv.v24i1-2.4583 ...

  9. D.I.M.E.F.I.L.: A Wordwide Campaign for Life

    Science.gov (United States)

    2007-05-01

    34 Anne Marie Oliver, and Paul F. Steinberg, The Road to Martyrs’ Square (New York: Oxford...Livingstone and Terrell Arnold, Fighting Back: Winning the War Against Terrorism (Lexington, DC Heath and Company 1986), 225. 117 Ibid., 226. 49...psychological Profiles Possible.” Studies in Conflict and Terrorism, 27: (February 2004): 283- 295. Livingstone, Neil and Terrell Arnold. Fighting Back

  10. Jazz Leader Helps a Band Take Giant Steps

    Science.gov (United States)

    Kelderman, Eric

    2008-01-01

    This article profiles Neil Slater, the longtime leader of the jazz program at the University of North Texas who encouraged both musical perfection and artistic freedom among his star pupils. Standards are high at North Texas, which has become a Camelot where aspiring jazz musicians have come to hone their skills since 1947, when it offered one of…

  11. Bush skazal ne sovsem to, tshto skazal

    Index Scriptorium Estoniae

    2006-01-01

    USA abivälisminister Euroopa ja Euraasia küsimustes Daniel Fried teatas, et NATO riigid toetavad Gruusia, Moldova ja Aserbaidžaani territoriaalset terviklikkust, kuid ei luba neil seda taastada relva abil. Abiminister selgitab, mida pidas USA president George W. Bush silmas, kui ta avaldas Riia tippkohtumisel toetust Gruusiale tema püüdlustes liituda NATO-ga

  12. Alkhurma Hemorrhagic Fever in Saudi Arabia

    Centers for Disease Control (CDC) Podcasts

    2010-10-28

    This podcast looks at the epidemiologic characteristics of Alkhurma Hemorrhagic Fever in humans in Najran City, Saudi Arabia. CDC epidemiologist Dr. Adam MacNeil discusses the severity and risk factors for the illness.  Created: 10/28/2010 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 11/17/2010.

  13. Plaadid / Priit Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Priit, 1957-

    2006-01-01

    Uutest heliplaatidest Neil Siamond "12 Songs", The Bamboos "Step It Up", Van Morrison "Pay The Devil", Mystery Jets "Making Dens", In Extremo "Raue Spree 2005", "Bossa n' Marley", Liv Kristine "Enter My Religion", Ugly Ducling "Bang The Buck", "Big Boi Presents", Youngblood Brass Band "Is That A Riott", Tosca "Souvenirs", Azymuth "Pure", Eels "With Strings", "Metal For The Masses"

  14. Put Rossii v WTO / Maksim Medvedkov

    Index Scriptorium Estoniae

    Medvedkov, Maksim

    2006-01-01

    Vene delegatsiooni juht Venemaa WTO-ga liitumise läbirääkimistel vastab küsimustele, mis puudutavad USA positsiooni neil läbirääkimistel, WTO-ga liitumise võimalikke tagajärgi Venemaale liitumise esimeses etapis, endiste NSVL-i vabariikide ja Venemaa vaheliste erimeelsuste võimalikku mõju Venemaa liitumisele WTO-ga

  15. Aga sellepärast, et on po... / Aleksandr Astrov

    Index Scriptorium Estoniae

    Astrov, Aleksandr

    2005-01-01

    Arutledes venekeelse valija hääletuskäitumise ümber juhib autor tähelepanu, et Eestis sätestab üks konkreetne seadus venelastele valimisõiguse, andes neile reaalse poliitilise jõu, teine aga piirab nende juurdepääsu ainult keele kaudu ligipääsetavatele eetikaressurssidele, mis võimaldaksid teha teadlikku valikut

  16. Head töötajad otsas / Robin Athey ; interv. Neeme Raud

    Index Scriptorium Estoniae

    Athey, Robin

    2006-01-01

    Konsultatsioonifirma Deloitte & Touche juhtimisuuringute analüütiku sõnul otsivad firmad väga spetsiifilise ettevalmistusega spetsialiste, keda tööjõuturul on aga raske leida. R. Athey uurimusest "On aasta 2008: kas teate, kus on teie töötajad?" Vt. samas: Näpunäide neile, kes unistavad palgatõusust ja karjäärist

  17. National Science Resources Center Project for Improving Science Teaching in Elementary Schools. Appendix A. School Systems With Exemplary Elementary Science Programs. Appendix B. Elementary Science Network

    Science.gov (United States)

    1988-12-01

    Glass, Lawrence, Deer Park High School Glass, Millard, K-12 Science Supervisor Bloomfield Municipal School District Glassman, Neil, Gleason, Steve...Superientendent Vaughn Municipal Schools Knop, Ronald N., Teacher Grissom Junior High School Knox, Amie, Director of Master Teacher Program W. Wilson...Science Supervisor Pequannock Township Public Schools Mercado , Roberto, Science Coordinator Colegio Radians, Inc. Merchant, Edwin, K-12 Science

  18. NOVA - Official Website | The Pluto Files

    Science.gov (United States)

    committees were assembled to come up with a new definition, the last of which was headed by my friend from . Under this definition, Pluto would remain a planet; Mike Brown's discovery would be one too. And as new doing this would bring scores of planets. NEIL DEGRASSE TYSON: Into the accounting of the planets in the

  19. Lewis Swift celebrated comet hunter and the people's astronomer

    CERN Document Server

    Kronk, Gary W

    2017-01-01

    This biography covers the life of Lewis Swift (1820-1913), who discovered 13 comets and nearly 1,200 other deep sky objects. All 13 comets found by Swift now bear his name, including three periodic comets with periods of 6 years (11P/Tempel-Swift-LINEAR), 9 years (64P/Swift-Gehrels), and 133 years (109P/Swift-Tuttle). Swift's enthusiasm and success as an amateur astronomer helped make him famous in the United States. With the help of others, Swift was able to buy a 16-inch refractor, the third largest telescope in the United States at the time. Hulbert Harrington Warner built "Warner Observatory" to house this telescope. As a prolific writer and lecturer, Swift's stories appeared in newspapers and magazines, while his lectures showed that he was able to explain anything in a way that everyone could understand.  When Warner went broke during the "Panic of 1893," Swift was forced to leave his home. Almost two dozen invitations arrived from around the United States asking him to bring his telescope to their ci...

  20. Triassic North American paleodrainage networks and sediment dispersal of the Chinle Formation: A quantitative approach utilizing detrital zircons

    Science.gov (United States)

    Blum, M. D.; Umbarger, K.

    2017-12-01

    The Triassic Chinle Formation is a fluvial succession deposited in a backarc setting across the present-day Colorado Plateau of the southwestern United States. Existing studies have proposed various mechanisms responsible for the unique stratigraphic architecture and depositional sequences of the Chinle. However, these studies lack necessary age control to correlate stratigraphic patterns with contemporaneous mechanisms. This study will collect new samples for detrital zircon analysis, as well as upgrade existing samples (to n=300) from Dickinson and Gehrels (2008), to improve the resolution of Triassic sediment provenance from source-to-sink. The improved dataset allows appraisal of the multiple provenance terranes that contributed to the Chinle depositional system to delineate and reconstruct paleodrainage patterns. The additional samples will be collected systematically from the base of the Chinle, and vertically throughout the section to capture a regional story of how the continental scale drainage reorganized through time. U-Pb ages of detrital zircons will be utilized to provide quantitative fingerprinting information to constrain interpretations for the origin and transport history of the Chinle fluvial succession in time and space.

  1. Routine Flights Become Overland Odysseys, Minus Clean Socks / Neil MacFarquhar

    Index Scriptorium Estoniae

    MacFarquhar, Neil

    2010-01-01

    President Toomas Hendrik Ilvese ja tema saatjaskonna tagasiteest Türgist Eestisse. Euroopa lennuliikluses kaose tekitanud Islandi vulkaanituha tõttu sõideti autode ja bussidega läbi üheksa riigi. Ülevaade artiklist ilmunud ka: Postimees 23. apr. 2010, lk. 13; Postimees : na russkom jazõke 23. apr. 2010, lk. 6. Ametlik visiit Türgi Vabariiki 15.-21.04.2010

  2. Thermophysical Properties of Nanoparticle-Enhanced Ionic Liquids (NEILs) Heat-Transfer Fluids

    Energy Technology Data Exchange (ETDEWEB)

    Fox, Elise B.; Visser, Ann E.; Bridges, Nicholas J.; Amoroso, Jake W.

    2013-06-20

    An experimental investigation was completed on nanoparticle enhanced ionic liquid heat transfer fluids as an alternative to conventional organic based heat transfer fluids (HTFs). These nanoparticle-based HTFs have the potential to deliver higher thermal conductivity than the base fluid without a significant increase in viscosity at elevated temperatures. The effect of nanoparticle morphology and chemistry on thermophysical properties was examined. Whisker shaped nanomaterials were found to have the largest thermal conductivity temperature dependence and were also less likely to agglomerate in the base fluid than spherical shaped nanomaterials.

  3. Detsibill : Heavy metal will never die! White label : Rakvere vabrik. Kuula / DJ Pickney Tiger

    Index Scriptorium Estoniae

    DJ Pickney Tiger, pseud., 1970-

    2006-01-01

    Rockmuusikast. Stupid F singlist "Nostalgilised helid". Heliplaatidest: Centleman "Confidence", Grupo Batuque "Ole ola - futbol bonito!", Teräsbetoni "Vaadimme metallia", Quantic "One Off's Remixes and B Sides", The Slackers "Peculiar", The Aggrolites "The Aggrolites", The Kooks "Inside in/Inside out", ZERO 7 "The Garden", Ignite "Our Darkest Days", Afi "December Underground", Pornstone "I Give MYself", Neil Young "Living With War"

  4. The Unaffiliated Unite

    Science.gov (United States)

    Lim, Victoria

    2011-01-01

    Neil Carter of Ridgeland, Miss., is about to take a leap of faith--based on his lack of faith. In a state where 91 percent of residents say they believe in God "with absolute certainty," according to the Pew Research Center, Carter began "coming out" recently to friends as an atheist. The 41-year-old special education teacher is also exploring…

  5. Treatment-Continuity of ADHD Compared Using Immediate-Release and Extended-Release MPH

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2005-07-01

    Full Text Available The continuity of methylphenidate (MPH therapy for ADHD in young Medicaid beneficiaries (ages 6 to 17 years treated with immediate-release (IR or extended-release (ER MPH formulations was compared in an analysis of statewide California Medicaid claims (2000-2003 conducted at Columbia University, New York; University of Pennsylvania, Philadelphia; and McNeil Pharmaceuticals, Fort Washington, PA.

  6. Snooki, Whale Sperm, and Google: The Unfortunate Extinction Of Librarians When They Are Needed Most

    Directory of Open Access Journals (Sweden)

    Margaux DelGuidice

    2012-02-01

    Full Text Available “Google can bring you back 100,000 answers. A librarian can bring you back the right one.” — Neil Gaiman The night before I was scheduled to return to work after summer vacation I was lying in bed, staring at the ceiling trying to quiet my thoughts and reset my body into work mode. Unfortunately I [...

  7. Q&A: The space crusader

    Science.gov (United States)

    Cowen, Ron

    2014-05-01

    US astronomer Neil deGrasse Tyson, director of New York's Hayden Planetarium, currently hosts the television series Cosmos -- an update of Carl Sagan's 1980 show -- broadcast in 181 countries and 45 languages. As it winds down, Tyson talks about the rich mix of science and pop culture, the 'neurosynaptic snapshot' of public responses to his tweets, and his momentous meeting with Sagan.

  8. 2005 Tri-Service Infrastructure Systems Conference and Exhibition. Volume 3, Track 3

    Science.gov (United States)

    2005-08-04

    Performance Measures for Prefabricated Submerged Concrete Breakwaters: Section 227 Cape May Point, New Jersey Demonstration Project, by Donald K Stauble...Slope Stability Evaluation of the Baldhill Dam Right Abutment , by Neil T. Schwanz Design and Construction of Anchored Bulkheads with Synthetic Sheet... Prefabricated Submerged Concrete Breakwaters: Section 227 Cape May Point, New Jersey Demonstration Project Donald K Stauble - Engineer Research

  9. Uuskasutus ja kompromissid / Triin Talk

    Index Scriptorium Estoniae

    Talk, Triin

    2015-01-01

    Ajalooliste hoonete kasutuses hoidmisest, neile uue funktsiooni andmisest. Vana-Võidu mõisa karjakastellist, mis kohandati Viljandi Kutseõppekeskuse õppehooneks. OÜ Paalakalda korrastatud Pajusi mõisa kuivatist. Väimela mõisa lauta rajatud Võrumaa Kutsehariduskeskuse puidutöötlemise ja mööblitootmise kompetentsikeskusest. Mooste mõisa meiereisse rajatud tervisekeskusest. Olustvere mõisakompleksi meiereisse rajatud Olustvere Teenindus- ja Maamajanduskooli meemajast

  10. Effects of Stress and Nicotine on Cognitive Function in Male and Female Rats

    Science.gov (United States)

    2016-05-20

    of Candidate: Raquel Mack Medical and Clinical Psychology Master of Science 2/9/2016 Thesis and Abstract Approved: ~62 Neil E. Grunberg, PhD ...Department of Military and Emergency Medicine Thesis Advisor Andrew Waters, PhD Department of Medical and Clinical Psychology Committee Member JIA...i EFFECTS OF STRESS AND NICOTINE ON COGNITIVE FUNCTION IN MALE AND FEMALE RATS by Raquel Mack Thesis

  11. Popnädal : Popuudised. Plaadid. Top 20 20 Raadio 2 / Aivar Meos

    Index Scriptorium Estoniae

    Meos, Aivar

    2002-01-01

    Industrial-ikooni Frontline Assembly ning projekti Delerium liige Rhys Fulber annab juulis välja oma uue sooloprojekti "Conjure One" albumi. Massive Attacki DVD-kogumikust "Eleven Promos". Ansambli The Orb plaadist "Daleth of Elphame". Rock-pop legendi Bryan Ferry uuest sooloplaadist "Frantic". Heliplaatidest "Ocean's Eleven" ja "Neil Young - Are You Passionate?". Edetabel eelmise nädala Raadio 2 enimmängitud lugudest

  12. Automated System for Holographic Lightfield 3D Display Metrology (HL3DM)

    Science.gov (United States)

    2015-04-01

    see that: Equation 7 - X = L* TAN (Ɵ)  Ɵ = ATAN(X/L) Equation 8 - L^2 + (X + W/2)^2 = P^2  P = sqrt( L^2 + (X + W/2)^2 ) Equation 9 - P...Physiol. Opt 2011, 31, 111–122. (2011, The College of Optometrists) 12. Nicolas S. Holliman, Neil A. Dodgson, Gregg E. Favalora, and Lachlan Pockett

  13. 75 FR 6397 - AMC USA, Inc. v. International First Service S.A. a/k/a IFS S.A, its Agents, Affiliated, Related...

    Science.gov (United States)

    2010-02-09

    ... Service USA, Inc. a/k/a IFS USA, Inc. d/b/a Global Wine Logistics USA Inc. a/k/a GWL USA, Inc., and Global... Wine Logistics USA Inc. a/k/a GWL USA, Inc. (``GWL USA''); Anita McNeil; International First Service... FEDERAL MARITIME COMMISSION [Docket No. 10-01] AMC USA, Inc. v. International First Service S.A. a...

  14. Confidence sets for asset correlations in portfolio credit risk

    Directory of Open Access Journals (Sweden)

    Carlos Castro

    2012-06-01

    Full Text Available Asset correlations are of critical importance in quantifying portfolio credit risk and economic capitalin financial institutions. Estimation of asset correlation with rating transition data has focusedon the point estimation of the correlation without giving any consideration to the uncertaintyaround these point estimates. In this article we use Bayesian methods to estimate a dynamicfactor model for default risk using rating data (McNeil et al., 2005; McNeil and Wendin, 2007.Bayesian methods allow us to formally incorporate human judgement in the estimation of assetcorrelation, through the prior distribution and fully characterize a confidence set for the correlations.Results indicate: i a two factor model rather than the one factor model, as proposed bythe Basel II framework, better represents the historical default data. ii importance of unobservedfactors in this type of models is reinforced and point out that the levels of the implied asset correlationscritically depend on the latent state variable used to capture the dynamics of default,as well as other assumptions on the statistical model. iii the posterior distributions of the assetcorrelations show that the Basel recommended bounds, for this parameter, undermine the levelof systemic risk.

  15. Molecular genetic identification of some wheat cultivars in the sudan

    International Nuclear Information System (INIS)

    Mekki, I. I; El Amin, H. B.

    2002-01-01

    Four wheat (Triticum aestivum L.) cultivars, namely condor, El-Nellene, Wadi El Neil and Debeira were characterized on biochemical and molecular bases. The biochemical ones were protein-banding patterns, using sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and isozymes to identify the biochemical genetic fingerprint of the four cultivars. Water-soluble protein-banding pattern showed no polymorphisms among the tested cultivars. The data from starch gel electrophoresis of enzymes, malate dehydrogenase (MDH), esterase (EST) and acid phosphate (ACPH) showed that the cultivars are monomorphic. Further trials to identify the molecular genetic fingerprints of the studied cultivars were carried out using RAPD-PCR twenty-five primers were tested to perform. RAPD-PCR analysis. From the PCR products, a phylogenetic map, i.e, dendrogram, was constructed for the studied cultivars which depicted tow groups. The first group contained Wadi El Neil and Deberia with 48.4% similarity, and the second group contained Condor and El Neileen with 100% similarity. There was no similarity between Condor and Debeira (100% dissimilarity). Therefor, these data can be used subsequently for genetic engineering research and for wheat breeding programmes in the Sudan.(Author)

  16. Geospace Plasma Dynamics Laboratory Annual Task Report (FY11)

    Science.gov (United States)

    2012-03-01

    Site Contractors: Nagendra Singh, Ph.D., Physicist , 0.5 MY Neil Grossbard, M.S., Mathematician , 0.7 MY Visitors: Publications: Articles in...PhD Project Manager Division Chief, RVB This report is published in the interest of scientific and technical...Annual Task Report (FY11) 5c. PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) 5d. PROJECT NUMBER 2311 Daniel Ober 5e. TASK NUMBER

  17. Institutsionaalsetest e-õpikutest üleriigiliseks avatud juurdepääsuga e-õppematerjalide kogumiks / Liisi Lembinen

    Index Scriptorium Estoniae

    Lembinen, Liisi

    2010-01-01

    TÜR käivitas 2008. aastal e-õpikute projekti, millega soovitakse anda üliõpilastele juurdepääs vanematele õppematerjalidele, mis on läbi müüdud või mille eksemplaarsus on raamatukogudes väike ning mida tuleb seetõttu kopeerida või skaneerida. Õpikud kuvatakse Ebrary andmebaasis ning neile on juurdepääs vaid Tartu Ülikooli arvutivõrgus

  18. 2005 Tri-Service Infrastructure Systems Conference and Exhibition. Volume 7, Tracks 7 and 8

    Science.gov (United States)

    2005-08-04

    Performance Measures for Prefabricated Submerged Concrete Breakwaters: Section 227 Cape May Point, New Jersey Demonstration Project, by Donald K Stauble...Slope Stability Evaluation of the Baldhill Dam Right Abutment , by Neil T. Schwanz Design and Construction of Anchored Bulkheads with Synthetic Sheet...Sinkholes near Switchyard + right d/s abutment wet areas D/S of embankment, muddy flows 1968-72 Emergency exploration / grouting 1975-79 Diaphragm walls

  19. Õuduse eelõhtu Kinomajas

    Index Scriptorium Estoniae

    2007-01-01

    PÖFFi korraldatud õudusfilmide festivalil HÕFF Haapsalu Kultuurikeskuses (22.-25. märtsini) näidatavad õudusfilmid "Frankensteini needus" (Terence Fischer; Suurbritannia, 1957) ja "Murtud" (Adam Mason, Simon Boyes; Suurbritannia, 2006)on 20.03. linal ka Tallinna Kinomajas. Neile eelneb Xavier Mendiki dokfilm "Menstrual Monsters" ning režissööri diskussioon produtdendi ja režissööri Howard Martiniga

  20. 商业即娱乐?

    Institute of Scientific and Technical Information of China (English)

    夏传

    2010-01-01

    @@ 和波普尔(Karl Popper,犹太裔思想家,批判理性主义的创始人)一样,尼尔·波兹曼(Neil Postman,世界著名的媒体文化研究者和批评家)提醒人们要警惕电视这个二十世纪的宠物.

  1. Kiire, mugav, odav? / Rein Raud

    Index Scriptorium Estoniae

    Raud, Rein, 1961-

    2006-01-01

    Ilmunud ka: Infopress 18. aug. nr. 33 lk. 151. TLÜ rektor viitab, et bakalaureusetase on vaid vahefaas, kus inimene on saanud spetsialiseerumiseks ettevalmistuse. Talle tundub, et Eesti praegune jõukusetase võimaldaks tagada vähemasti koha tasuta magistriõppes kõigile neile ülikoolilõpetajatele, kelle bakalaureuseõpingute tulemus on ületanud mingi teatava künnise, ning loobuda õpingute nominaalaja fetišeerimisest

  2. Airpower in Mass Atrocity Response Operations (MARO)

    Science.gov (United States)

    2012-06-01

    Prime Minister Tony Blair outlined the moral tone and justification for NATO action saying, “We are taking this action to prevent Milosevic from...parallel, but soon, military targets north of the line 82 Carla Anne Robbins , Thomas E. Ricks, and...Responsibility To Protect, 12 January 2009. Robbins , Carla Anne, Thomas E. Ricks, and Neil King, Jr. “Milosevic’s Resolve Spawned Unity, Wider Bombing List in

  3. Hullud päevad von Krahlis

    Index Scriptorium Estoniae

    2006-01-01

    Von Krahli Teatris mängitakse neil päevi neli korda Peeter Jalaka lavastuses Tõnu Kõrvitsa kammeroopereid "Tuliaed" ja "Mu luiged, mu mõtted", mille aluseks on luuletaja Marie Heibergi saatus. Libreto autor on Maarja Kangro. Kammerooperid tulevad lavale Von Krahli Teatri ja Nargen Opera koostöös. Esitavad Kädy Plaas, Helen Lokuta, Nargen Opera koor ja Tallinna Kammerorkester, dirigent Tõnu Kaljuste

  4. Atoms – How Small, and How Large!

    Indian Academy of Sciences (India)

    IAS Admin

    found in the Bohr atom model, the birth centenary of which is celebrated in the year 2013. Neils Bohr intro- duced in his model the quantization (occurrence of dis- ... free or isolated H-atom is of the order of 1 Å = 10. −10 m. The quantity a0 is quite fundamental and it serves as a unit of length in the atomic–molecular physics.

  5. 21st Century Military Operations in a Complex Electromagnetic Environment

    Science.gov (United States)

    2015-07-01

    Natalie Crawford RAND Corporation RDML Jon P. Cryer, USN (ret) Northrop Grumman Mr. Stephen Cummings Raytheon Dr. Eric Evans MIT Lincoln...Heyer U.S. Navy Ms. Leslie Litton U.S. Army Dr. Charles Perkins National Reconnaissance Office Mr. Marvin Potts U.S. Air Force Dr. Stephen ...Neil Fox Virginia Tech Applied Research Corporation Ms. Hannah Freeman Strategic Analysis, Inc. Mr. Marcus Hawkins Strategic Analysis, Inc. Dr

  6. Scots scientists dismiss Apollo mission doubts university team deals with the conspiracies

    CERN Multimedia

    Simpson, Cameron

    2004-01-01

    "Scientists from a Scottish university are going walkabout to combat the sceptics who claim US astronaut Neil Armstrong never set foot on the moon. The conspiracists claim the Apollo moon landings of the 60s and 70s were faked by Nasa in a TV studio in an attempt to help America claim victory in the space race with the former Soviet Union" (1 page)

  7. Ajalehtede lõpp / Abdul Turay

    Index Scriptorium Estoniae

    Turay, Abdul, 1967-

    2011-01-01

    1843. aastast ilmunud Briti tabloidi News of the World suleti erakõnede pealtkuulamise tõttu. News of the World'i peadirektorit Rebekah Brooksi ja meediaparun Rupert Murdochi kardavad isegi poliitikud, kes ei julge neid avalikult kritiseerida. Ajalehti juhib kitsas ring inimesi ja neil on liiga suur võim käes. Eestis valitseb teistsugune olekord - ükski poliitik ei karda tõsiselt ühtegi ajakirjanikku

  8. Toward Determining the Comprehensibility of Machine Translations

    Science.gov (United States)

    2012-01-01

    responses to a stimulus (Macmillan and Creelman , 1991). It has been applied in areas such as lie detection (truth/lie), inspection (ac- ceptable...1-1/(2N) (Macmil- lan and Creelman , 1991). Negative values, which usually indicate response confusion, were eliminated. The results of...Macmillan, Neil and C. Douglas Creelman . (1991). Detection theory: A User’s guide. Cambridge Univer- sity Press, pp. 10 &125. Marchant

  9. Perspectives of Survivors on Military Suicide Decedents’ Life Stressors and Male Gender Role Stress using the Male Gender Role Stressor Inventory (MGRSI)

    Science.gov (United States)

    2013-03-26

    Suicide Psychiatric diagnoses. Antisocial Personality Disorder is diagnosed three times more often in men than women (American Psychiatric Association...Finally, using a two-year prospective design, researchers determined that a diagnosis of borderline     15   personality disorder resulted in...which refers to “a psychological state in which socialized gender roles have negative consequences for the person or others” (p. 362, O’Neil, 2008) and

  10. Telecast of Astronauts Armstrong and Aldrin by the Lunar Module ladder

    Science.gov (United States)

    1969-01-01

    Astronauts Neil A. Armstrong (on left), commander; and Edwin E. Aldrin Jr., lunar module pilot, are seen standing by the Lunar Module ladder in this black and white reproduction taken from a telecast by the Apollo 11 lunar surface television camera during the Apollo 11 extravehicular activity. This picture was made from a televised image received at the Deep Space Network tracking station at Goldstone, California.

  11. Le prochain Einstein sera-t-il africain ? | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    23 oct. 2012 ... L'idée de créer l'AIMS a germé dans l'esprit du physicien sud-africain Neil Turok, qui dirige le Perimeter Institute for Theoretical Physics, sis à Waterloo, au Canada. L'AIMS a pour objectif de favoriser la production scientifique et technique de l'Afrique et d'aider le continent à mettre les sciences et la ...

  12. Viewing Extensive Reading from Different Vantage Points

    Science.gov (United States)

    Stoller, Fredricka L.

    2015-01-01

    Some years ago (in about 2007), this author was asked by Professor Neil J. Anderson, known for his expertise in second language (L2) reading, to identify his top-five priorities for teachers of L2 reading. As it turns out, it was an interesting intellectual exercise to narrow down key issues in teaching L2 reading to a grand total of five. To…

  13. Comparison of Neural Network and Linear Regression Models in Statistically Predicting Mental and Physical Health Status of Breast Cancer Survivors

    Science.gov (United States)

    2015-07-15

    34 Name of Candidate: Alicia Ottati Doctor of Philosophy Degree June 23 , 2015 DISSERTATION AND ABSTRACT APPROVED: ifr . Neil . Grunberg DATE: ’"f...diagnosis can impact the late and long-term effects experienced by breast cancer survivors. Staging is a classification method used to describe the...designed to identify complex, nonlinear relationships may provide a better understanding of how treatment received impacts breast cancer survivors

  14. A Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These “Spare Tires” Have an Evolved Function?

    Science.gov (United States)

    2015-01-01

    Uncontrolled inflammation or oxidative stress generates electron-deficient species that oxidize the genome increasing its instability in cancer. The G-quadruplex (G4) sequences regulating the c-MYC, KRAS, VEGF, BCL-2, HIF-1α, and RET oncogenes, as examples, are targets for oxidation at loop and 5′-core guanines (G) as showcased in this study by CO3•– oxidation of the VEGF G4. Products observed include 8-oxo-7,8-dihydroguanine (OG), spiroiminodihydantoin (Sp), and 5-guanidinohydantoin (Gh). Our previous studies found that OG and Gh, when present in the four G-tracks of the solved structure for VEGF and c-MYC, were not substrates for the base excision repair (BER) DNA glycosylases in biologically relevant KCl solutions. We now hypothesize that a fifth G-track found a few nucleotides distant from the G4 tracks involved in folding can act as a “spare tire,” facilitating extrusion of a damaged G-run into a large loop that then becomes a substrate for BER. Thermodynamic, spectroscopic, and DMS footprinting studies verified the fifth domain replacing a damaged G-track with OG or Gh at a loop or core position in the VEGF G4. These new “spare tire”-containing strands with Gh in loops are now found to be substrates for initiation of BER with the NEIL1, NEIL2, and NEIL3 DNA glycosylases. The results support a hypothesis in which regulatory G4s carry a “spare-tire” fifth G-track for aiding in the repair process when these sequences are damaged by radical oxygen species, a feature observed in a large number of these sequences. Furthermore, formation and repair of oxidized bases in promoter regions may constitute an additional example of epigenetic modification, in this case of guanine bases, to regulate gene expression in which the G4 sequences act as sensors of oxidative stress. PMID:26405692

  15. Access to Behavioral Health Care for Geographically Remote Service Members and Dependents in the U.S.

    Science.gov (United States)

    2015-01-01

    13, No. 3, 2007, pp. 142–147. Fuller, Jeff, Jane Edwards , Nicholas Procter, and John Moss, “How Definition of Mental Health Problems Can Influence...http://srph.tamhsc.edu/centers/rhp2010/08Volume2mentalhealth.pdf Germain, Vanessa , Andre Marchand, Stephane Bouchard, Marc-Simon Drouin, and...Press Workshop Summary,” 2012. Iversen, Amy C., Lauren van Staden, Jamie H. Hughes, Neil Greenberg, Matthew Hotopf, Roberto J. Rona, Graham

  16. Fire Service Emergency Management Handbook

    Science.gov (United States)

    1985-01-01

    Adapted from Formulating Public Policy in Emergency Management Course Book and ResourceMRanual for Public OTTicials, ILMA Emergency Management Institute...659-2447 (202) 785-2757 Christian Reformed World Relief Presbyterian Church in U.S. Committee General Assemby Mission Board C. Neil Molenaar 341 Ponce...Healer, Mind as Slayer. New York: Delta Books , 1977. 86B:6 B-45 4) Mitchell, J.T., & Resnik, HLP: Emergency Response to Crisis: A Crisis Intervention

  17. The treatment of female stress urinary incontinence: an evidenced-based review

    OpenAIRE

    Cameron, Anne P; Haraway, Allen McNeil

    2011-01-01

    Anne P Cameron, Allen McNeil HarawayDepartment of Urology, Division of Neurourology and Pelvic Floor Reconstruction, University of Michigan Health System, Ann Arbor, MI, USAObjective: To review the literature on the surgical and nonsurgical treatment options for stress urinary incontinence in women, focusing exclusively on randomized clinical trials and high quality meta-analyses.Materials and methods: A computer-aided and manual search for published randomized controlled trials and high qual...

  18. Curiosities of the sky

    CERN Document Server

    Serviss, Garrett P

    2012-01-01

    Long before figures like Carl Sagan and Neil deGrasse Tyson simplified astronomy for popular consumption, Garrett P. Serviss was traveling the United States with an early version of a PowerPoint presentation to teach people about eclipses, the orbit of the planets, and other celestial concepts. This basic introduction to the subject is simple and enjoyable enough to ensure that science-phobes or young readers won't be turned off.

  19. Kas vajame maavalitsust? / Egon Valdaru

    Index Scriptorium Estoniae

    Valdaru, Egon

    2007-01-01

    Ilmunud ka: Pärnu Postimees, 10. mai 2007, lk. 19; Oma Saar, 15. mai 2007, lk. 3; Harjumaa, 15. mai 2007, lk. 2; Koit, 15. mai 2007, lk. 6; Virumaa Teataja, 18. mai 2007, lk. 11; Põhjarannik, 22. mai 2007, lk. 2; Severnoje Poberezhje, 22. mai 2007, lk. 2. Autor peab maavalitsuste kaotamist olukorras, kus neil on palju kohustusi, mida keegi teine ei saa ega suuta täita, ilmselgeks rumaluseks

  20. 2005 Tri-Service Infrastructure Systems Conference and Exhibition. Volume 6, Track 6

    Science.gov (United States)

    2005-08-04

    Performance Measures for Prefabricated Submerged Concrete Breakwaters: Section 227 Cape May Point, New Jersey Demonstration Project, by Donald K Stauble...Wielputz Slope Stability Evaluation of the Baldhill Dam Right Abutment , by Neil T. Schwanz Design and Construction of Anchored Bulkheads with Synthetic Sheet...Towards Right Abutment . Note Debris From the May ’03 High Water Mark. Clearwater Dam - Sinkhole 16 January 2003 Top of dam elevation 608 Top of Sinkhole

  1. 2005 Tri-Service Infrastructure Systems Conference and Exhibition. Volume 10, Track 12

    Science.gov (United States)

    2005-08-04

    Performance Measures for Prefabricated Submerged Concrete Breakwaters: Section 227 Cape May Point, New Jersey Demonstration Project, by Donald K Stauble...Wielputz Slope Stability Evaluation of the Baldhill Dam Right Abutment , by Neil T. Schwanz Design and Construction of Anchored Bulkheads with Synthetic Sheet... abutment ) 5 days into initial filling @ pool . • July 1968 structural inspection cited areas of spalling concrete and water flowing down stair treads in the

  2. Salmonella causada por reptiles y anfibios en guarderías (Salmonella Infections Caused by Reptiles and Amphibians in Childcare Centers)

    Centers for Disease Control (CDC) Podcasts

    2013-02-07

    Traducción al español de la entrevista con el Dr. Neil Vora, funcionario del EIS de los CDC, sobre su artículo acerca de las infecciones por Salmonella causadas por reptiles y anfibios en guarderías.  Created: 2/7/2013 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 2/26/2013.

  3. A Human-Automation Interface Model to Guide Automation Design of System Functions: A Way to Achieve Manning Goals in New Systems

    Science.gov (United States)

    2005-12-01

    Manual (Army) FoS Family of Systems FRMV FCS Recovery and Maintenance Vehicle GDLS General Dynamics Land Systems HFE Human Factors Engineering...Thanks goes to our CRADA partners at BAE Systems (formerly UDLP) in Santa Clara, CA. Jeff Powers, Doug Neil, Gene Brennan, and Ron Natividad were eager...above in the HFE implications, MWL can be modeled during system design to assess if it is reasonable throughout system functional flow. Besides

  4. Motivation Theory Through Maslow's Hierarchy of Needs in Limitless

    OpenAIRE

    Kristanto, Joko

    2013-01-01

    Film Limitless adalah sebuah film fiksi ilmiah garapan Neil Burger yang menceritakan seorang pemuda di New York yang nyaris jadi gelandangan karena kehilangan pekerjaannya. Bahkan kekasihnya pun meninggalkannya karena tidak banyak yang bisa diharapkan dari pemuda ini. Tetapi ia kemudian bertemu dengan pil yang mengubah seluruh hidupnya. Pil ini membuatnya menjadi orang yang sangat cerdas melebihi manusia manapun. Ia bukan hanya bisa mengembalikan kehidupannya yang sudah hancur itu dengan kece...

  5. Direct and indirect effects of paliperidone extended-release tablets on negative symptoms of schizophrenia

    OpenAIRE

    Bossie, Cynthia

    2008-01-01

    Ibrahim Turkoz, Cynthia A Bossie, Bryan Dirks, Carla M CanusoOrtho-McNeil Janssen Scientific Affairs, LLC, Titusville, NJ, USAAbstract: Direct and indirect effects of the new psychotropic paliperidone extended-release (paliperidone ER) tablets on negative symptom improvement in schizophrenia were investigated using path analysis. A post hoc analysis of pooled data from three 6-week, double-blind, placebo-controlled studies of paliperidone ER in patients experiencing acute exacerbation was con...

  6. Preliminary Modeling of Acoustic Detection Capability for the Drifting Arctic Monitoring System

    Science.gov (United States)

    2015-02-01

    Sedimentary Basins in the Arctic, Polarforschung, 69, 243–249. [22] Poore, Richard Z, Ishman, Scott E, Phillips, R Lawrence, and McNeil, David H (1994...93, 1784. [28] Metzler, Adam M, Collis , Jon M, and Siegmann, William L (2012), Modeling low-frequency seismo-acoustic propagation in the Arctic using a...Atlantic. [50] Shnidman, David A (1998), Binary integration for Swerling target fluctuations, Aerospace and Electronic Systems, IEEE Transactions on

  7. Olgem ajaloo suhtes ausad / Olev Reemet, Bella Sagarova

    Index Scriptorium Estoniae

    Reemet, Olev

    2006-01-01

    Johannes Hindi kauaaegsed kaastöötajad teatavad, et J. Hindi küsimuses olid Eesti juhtkonna poole pöördumisel neile kõik uksed suletud ning Arnold Rüütel oli ainus, kes neid Eestis vastu võttis. J. Hindi küsimuse tõstatasid NSVL-i keskkomitee ja Karl Vaino. Autorid kutsuvad meediat üles mitte avaldama artikleid, kus J. Hindi nime kasutatakse poliitikute omavahelises võitluses

  8. System Shock: The Archetype of Operational Shock

    Science.gov (United States)

    2017-05-25

    the battle space. They can also facilitate a much greater understanding of the variables involved in each party’s decision - making process. However...system shock nests within current US Army Unified Land Operations doctrine. In order to test the utility of system shock theory to Gray Zone...23 Neil E. Harrison, “Thinking about the World We Make ” in Chaos Theory in the Social Sciences: Foundations and Applications

  9. Apollo 11 crew on ship during water egress training in Gulf of Mexico

    Science.gov (United States)

    1969-01-01

    The prime crew of the Apollo 11 lunar landing mission relaxes on the deck of the NASA Motor Vessel Retriever prior to participating in water egress training in the Gulf of Mexico. Left to right, are Astronauts Edwin A. Aldrin Jr., lunar module pilot; Neil A. Armstrong, commander; and Michael Collins, command module pilot. In the background is Apollo Boilerplate 1102 which was used in the training exercise.

  10. Mineralization of TNT, RDX, and By-Products in an Anaerobic Granular Activated Carbon-Fluidized Bed Reactor

    Science.gov (United States)

    2003-04-01

    pipe fitters and safety personnel who constructed and installed the system. CERL personnel include Don Cropek, Pat Kemme, Neil Adrian and Clint Arnett...al. (2000), demonstrated the sequential conversion of the nitro-groups to amino-groups in TNT degradation, and Adrian and Sutherland , 1998...dinitrotoluene extended the research to TNT, RDX and pinkwater (Adrian and Sutherland , 1998, VanderLoop et al., 1998 and Hwang et al., 2000). Initial pilot

  11. Former astronaut Armstrong witnesses STS-83 launch

    Science.gov (United States)

    1997-01-01

    Apollo l1 Commander Neil A. Armstrong and his wife, Carol, were among the many special NASA STS-83 launch guests who witnessed the liftoff of the Space Shuttle Columbia April 4 at the Banana Creek VIP Viewing Site at KSC. Columbia took off from Launch Pad 39A at 2:20:32 p.m. EST to begin the 16-day Microgravity Science Laboratory-1 (MSL-1) mission.

  12. Is There Future Utility in Nuclear Weapons Nuclear Weapons Save Lives

    Science.gov (United States)

    2014-02-13

    operate with relative impunity short of large-scale conflict. Some point to a nuclear India and Pakistan as an example of instability concern. In...1997, South Asia observer Neil Joeck argued that “ India and Pakistan’s nuclear capabilities have not created strategic stability (and) do not reduce...elimination of illiteracy , provision of sustainable energy, debt relief for developing countries, clearance of landmines and more has been estimated

  13. Complex Information Coordination Performance: Differential Changes in Working Memory Contributions Following Training. Cognitive Components of Information Coordination

    Science.gov (United States)

    1993-06-30

    UNIVERSITY DEPARTMENT OF PSYCHOLOGY EDUCATION BUILDING TALLAHASSEE FL 32306 W LAFAYETTE IN 47907 DR NEIL DORANS DR RODNEY COCKING EDUCATIONAL TESTING SERVICE...DR LORRAINE D EYDE PSYCHOLOGY DEPARTMENT US OFFICE OF PERSONNEL MGMT IOWA STATE UNIVERSITY OFFICE OF PERSONNEL RESEARCH AMES IA 50010 AND DEVELOP...judgments were performed under the added cognitive load of the coordination task. Method Subjects A total of eighty subjects were tested , with one

  14. Brenner Neil, New States Spaces. Urban Governance and the Rescaling of Statehood

    Directory of Open Access Journals (Sweden)

    Bernard Jouve

    2007-05-01

    Full Text Available La lecture de cet ouvrage suscite à la fois le respect et la gratitude. Le respect car, N. Brenner, jeune sociologue à la carrière fulgurante, nous propose une mise en perspective et un état des lieux qui était devenu absolument indispensable de la recherche en sciences sociales portant sur les liens entre la transformation des Etats européens et la place qu’occupent les villes dans un ordre politique et économique en recomposition. Pour ceux qui s’intéressent à ce vaste chantier scientifique...

  15. Poly(alkylene oxide) Copolymers for Nucleic Acid Delivery

    Science.gov (United States)

    2012-07-17

    Poly(alkylene oxide) Copolymers for Nucleic Acid Delivery Swati Mishra1,#, Lavanya Y. Peddada1,#, David I. Devore3,4, and Charles M. Roth1,2...Neil Raju for assistance with figures. Biographies Swati Mishra received her Ph.D. in Biomedical Engineering and Biotechnology from the University of...Kleiman N, Anderson RD, Gottlieb D, Karlsberg R, Snell J, Rocha- Singh K. Results from a phase II multicenter, double-blind placebo-controlled study of Del

  16. Gulf War Women’s Health Cohort

    Science.gov (United States)

    2017-10-01

    of 92% (n=484) and 87% (n=456), respectively (5). Measures included items concerning general physical health and gender-specific health items. In...for which medical treatment or health services were sought. Multiple statistical analyses were used to describe women’s physical and emotional health ...Women’s physical and mental health sequellae of wartime service. Nurs Clin N Am 2004;39:53- 68. 2. Coughlin SS, McNeil RB, Provenzale DT, Dursa EK

  17. A Survey of Electronics Obsolescence and Reliability

    Science.gov (United States)

    2010-07-01

    standardisation, interoperability, cosmetics , ease of use, robustness, shielding, filtering, and interference.  Level 6. System to System connection (e.g...The Problem with Function Points”, IEEE Software, Vol. 14, Issue 2, pp. 29-31. 83. T. Hall and N. Fenton (Mar./Apr. 1997) “Implementing Effective...software project failure: a case study”, The Journal of Systems and Software Vol. 49, pp. 177-192. 110. N. Fenton and M. Neil (1999) “Software

  18. Apollo Anniversary: Moon Landing "Inspired World"

    Institute of Scientific and Technical Information of China (English)

    John Roach; 李然

    2004-01-01

    @@ On July 20, 1969, at 10:56 p.m. ET, Apollo 11 astronaut Neil Armstrong stepped onto the surface of the moon and said, "That' s one small step for man,one giant leap for mankind." Thirty-five years later, Steven Dick, NASA's chief historian at the space agency's headquarters in Washington, D.C. , said that a thousand years from now, that step may be considered the crowning① achievement of the 20th century.

  19. International Criminal Law: Over-studied and Underachieving?

    OpenAIRE

    Van Sliedregt, E

    2016-01-01

    In his recent review of Neil Boister's book, An Introduction to Transnational Criminal Law, Robert Currie praises the author for shedding light on a field of law that has suffered from inattention. Transnational criminal law (TCL), the 'other' branch of what was traditionally called international criminal law, has been overshadowed by international criminal law 'proper' (ICL). The establishment of international criminal tribunals after the end of the Cold War, culminating in the establishment...

  20. Fibre Laser Welding of HY-80 Steel: Procedure Development and Testing

    Science.gov (United States)

    2010-09-01

    2 Welding The material used in this study was quenched and tempered martensitic HY80 steel which conforms to MIL-S-1621 [2]. The testing...Journal, 1977. [4] AWS, D1.6 in Structural Welding Code Stainless Steel . 2007, American Welding Society: Miami Florida. [5] DefStan, 02-770 Part 2...Canada Fibre Laser Welding of HY-80 Steel Proceedure Development and Testing Christopher Bayley DLP Neil Aucoin DLP Xinjin Cao NRC IAR AMTC Technical

  1. Field Demonstration of Propane Biosparging for In Situ Remediation of N-Nitrosodimethylamine (NDMA) in Groundwater

    Science.gov (United States)

    2015-12-01

    ER-200828 DECEMBER 2015 Paul B. Hatzinger, Ph.D. David Lippincott, P.G. CB&I Federal Services, LLC. Distribution Statement A This...Neil Harvey, Paul Weinhardt, and Sheryl Streger of CB&I were vital to project success. Their efforts ultimately lead to the quality experimental...Annable, M.D., K. Hatfield, J. Cho, H. Klammler, B.L. Parker, J.A. Cherry , and P.S.C. Rao. 2005. Field-scale evaluation of the passive flux meter

  2. Behavioral and Biological Effects of Prenatal Stress and Social Enrichment: Relevance to Heart Disease

    Science.gov (United States)

    2009-08-17

    whom I am eternally grateful. The first person is my coach and mentor, Neil E. Grunberg, Ph.D. There is no one who knows the " sport " of training...reported that prenatally stressed male rats actually showed a demasculinization and feminization of their sexual behavior. If female rats show a...masculinization in response to prenatal stress and males show a feminization , then the current findings could be viewed in the context of femaleS

  3. Factors Impacting Intra-District Collaboration: A Field Study in a Midwest Police Department

    Science.gov (United States)

    2018-03-01

    Delinquency 50, no. 4 (2004): 516–541; Neil Brewer, Patricia Mitchell, and Nathan Weber, “Gender Role, Organizational Status, and Conflict Management...attendance from both the patrol and detective divisions. During weekly COMPSTAT meetings, P6 explains, the staff goes over statistics and “the...and White Police Officers.” Crime & Delinquency 50, no. 4 (2004): 516–541 Thibault, Edward A., Lawrence M. Lynch, R. Bruce McBride, and Gregory Walsh

  4. Introduction, Copyright's Paradox

    OpenAIRE

    Netanel, Neil

    2008-01-01

    The United States Supreme Court famously labeled copyright “the engine of free expression” because it provides a vital economic incentive for much of the literature, commentary, music, art, and film that makes up our public discourse. Yet today’s greatly expanded copyright law often does the opposite—it can be used to quash news reporting, political commentary, church dissent, historical scholarship, cultural critique, and artistic expression. In Copyright’s Paradox, Neil Weinstock ...

  5. Proceedings from the ETS and ARI Emotional Intelligence Workshop held in Princeton, New Jersey on November 13-15, 2003. Volume 1. Sessions 1 and 2

    Science.gov (United States)

    2003-11-01

    883. MacKinnon, Neil J. 1994. Symbolic Interactionism as Affect Control. Albany: State University of New York Press. _____ and Leo Keating. 1989...The Case of Paralegals.” Symbolic Interaction 24:343-366. -----. 2002. “Upsetting the Balance and Evening the Field: The Effects of Client Contact on...State University of New York Press. Thoits, Peggy A. 1996. “Managing the Emotions of Others.” Symbolic Interaction 19:85-109. 110 Proceedings from

  6. World of Warcraft Meets War Plan Orange: The Military Utility of Collaborative Problem Solving in a Virtual Environment

    Science.gov (United States)

    2011-06-01

    hundred years, this faith in the wisdom of crowds is well founded; many entrepreneurs have already built multi-million dollar businesses around the...the age group that makes up the younger portion of the Air Force is called the Millennial Generation, Generation Y, or just Millennials . Born...Strauss and Neil Howe as definitive, the earliest Millennial joined the Air Force in 2000 and can retire in 2018, around the time the last Millennial

  7. Sustainable Range Management of RDX and TNT by Phytoremediation with Engineered Plants

    Science.gov (United States)

    2016-04-01

    pH 6.5. Change in absorbance at 340 nm was measured over 1 min. Significant difference from wild-type (WT) is shown by an asterisk and determined by...FINAL REPORT Sustainable Range Management of RDX and TNT by Phytoremediation with Engineered Plants SERDP Project ER-1498 APRIL 2016...by Phyoremediation with Engineered Plants 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER ER-1498 Neil C

  8. Global economic burden of schizophrenia: response to authors’ reply

    Directory of Open Access Journals (Sweden)

    Neil AL

    2017-02-01

    Full Text Available Amanda L Neil,1 Vaughan J Carr2,3 1Menzies Institute for Medical Research, The University of Tasmania, Hobart, TAS, 2Research Unit for Schizophrenia Epidemiology, University of New South Wales, Sydney, NSW, 3Department of Psychiatry, School of Clinical Sciences, Monash University, Melbourne, VIC, AustraliaFor clarification, we undertook bottom-up costing using individual participant data from the Low Prevalence Disorders Study in our costing study.1 We did not use the data reported in the study by Carr et al2 as asserted by Chong et al.3 Chong et al have thus misunderstood and thus misrepresented our methodology in both their systematic review4 and their response to our letter.5 Authors' reply  Huey Yi Chong,1 Nathorn Chaiyakunapruk1–41School of Pharmacy, Monash University Malaysia, Selangor, Malaysia; 2Center of Pharmaceutical Outcomes Research (CPOR, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; 3School of Pharmacy, University of Wisconsin, Madison, USA; 4School of Population Health, University of Queensland, Brisbane, Australia We thank Dr Neil and Professor Carr for their clarification on the data source used in their study.1 In this regard, we would like to highlight one of the most common challenges when conducting any systematic review, for example economic burden of schizophrenia in this case – the marked diversity in reporting among the included studies, which increases the likelihood of any potential misinterpretation. In convergence with a number of published systematic reviews of economic burden studies,2–5 there has been a consistent call for a more explicit reporting in various aspects of an economic burden study, thus readability and transparency can be enhanced. However, a standardized guide/checklist for conducting and reporting economic burden is yet to be available. On the final note, we strongly urge for the development of such a guidance document

  9. Detection of Xenotropic Murine Leukemia Virus-Related Virus (XMRV) in Gulf War Illness: Role in Pathogenesis or Biomarker?

    Science.gov (United States)

    2014-12-01

    Belz, C.M. Smith, R.J. Steptoe, W.R. Heath, K. Shortman, J.A. Villadangos, Most lymphoid organ dendritic cell types are phenotypically and...Nicolas, D. Kaiserlian, Innate CD4+CD25+ regulatory T cells are required for oral tolerance and inhibition of CD8+ T cells mediating skin inflammation...140] M. Guadalupe, E. Reay, S. Sankaran, T. Prindiville, J. Flamm, A. McNeil, S. Dandekar, Severe CD4+ T- cell depletion in gut lymphoid tissue during

  10. Myers-Briggs Type Indicators and Kirton Adaption-Innovation Inventory Correlations.

    Science.gov (United States)

    1994-04-01

    future and strategic planning to address those assumptions. As we grow forward into 27 the 21st Century, our ability to exceed our expectations, as...J. King, Ph.D., "Eagles, Otters, and Unicorns ," Industry Week, March 1990, page 31. 42. Ibid., page 32. 32 p 43. Neil Anderson, Gillian Hardy, and...Subordinates?" Credit World. (July/August 1990): 19-23. Grossman, Stephen R. and Margaret J. King, Ph.D. "Eagles, Otters, and Unicorns ." Industry Week

  11. Feasibility of Wii Fit training to improve clinical measures of balance in older adults

    OpenAIRE

    Bieryla KA; Dold NM

    2013-01-01

    Kathleen A Bieryla, Neil M DoldBiomedical Engineering Department, Bucknell University, Lewisburg, PA, USABackground and purpose: Numerous interventions have been proposed to improve balance in older adults with varying degrees of success. A novel approach may be to use an off-the-shelf video game system utilizing real-time force feedback to train older adults. The purpose of this study is to investigate the feasibility of using Nintendo's Wii Fit for training to improve clinical measu...

  12. Fab the coming revolution on your desktop : from personal computers to personal fabrication

    CERN Document Server

    Gershenfeld, Neil

    2005-01-01

    What if you could someday put the manufacturing power of an automobile plant on your desktop? According to Neil Gershenfeld, the renowned MIT scientist and inventor, the next big thing is personal fabrication-the ability to design and produce your own products, in your own home, with a machine that combines consumer electronics and industrial tools. Personal fabricators are about to revolutionize the world just as personal computers did a generation ago, and Fab shows us how.

  13. A more accurate HR diagram for the cooler stars

    International Nuclear Information System (INIS)

    Keenan, P.C.

    1978-01-01

    The author's objective is to classify the fine structure in the pattern in the luminosity-spectrum domain, and thus to define more precisely the borders of zones which are either occupied or avoided by stars of a given population. It is this pattern which is compared with theoretical evolutionary tracks and it is such a diagram based on the revised MK classification of the recent Atlas of Keenan and McNeil (1976) that is presented. (Auth.)

  14. AMPK activation: a therapeutic target for type 2 diabetes?

    OpenAIRE

    Saha, Asish; Coughlan,Kimberly; Valentine,Rudy; Ruderman,Neil

    2014-01-01

    Kimberly A Coughlan, Rudy J Valentine, Neil B Ruderman, Asish K Saha Endocrinology and Diabetes, Department of Medicine, Boston University Medical Center, Boston, MA, USA Abstract: Type 2 diabetes (T2D) is a metabolic disease characterized by insulin resistance, β-cell dysfunction, and elevated hepatic glucose output. Over 350 million people worldwide have T2D, and the International Diabetes Federation projects that this number will increase to nearly 600 million by 2035. There is a...

  15. The Fourteenth International Meeting on Time-Resolved Vibrational Spectroscopy (TRVS XIV)

    Science.gov (United States)

    2010-02-03

    conferences covering the use of advanced vibrational spectroscopy for the use of studying time-dependent molecular processes in chemistry, physics ...Netherlands a.huertaviga@uva.nl Neil Hunt Dept of  Physics , University of Strathclyde United Kingdom nhunt@phys.strath.ac Koichi Iwata Gakushuin University...Dasgupta Mark Creelman Sangdeok Shim Biochemical Reaction Dynamics, , , UC B k ler e ey 11:50 AM C W. Zinth, W. J. Schreier, J. Kubon, N. Regner, K

  16. The SME (Structure-Mapping Engine) User’s Manual (SME Version 2E)

    Science.gov (United States)

    1988-12-30

    It is prior to this step that one might want to think about wether to modify any system parameters (e.g., print the match hypotheses, print only the...Wshington, DC 20390 Department of Psychology Carnegie-Mellon University Dr. Judith Orsanu Schenley Park Dr. Harold P. O’Neil, Jr. Basic Research Office...Pinker Baltimore, MD 21201 Department of Psychology ElO-018 Dr. Judith W. Segal MIT Dr. J. Wesley Regian OERI Cambridge, MA 02139 AFHRL/IDI 556 New

  17. Mathematics Education Problems and Attempts to Solve Them in Nowadays Lithuanian School

    OpenAIRE

    Malaukytė Ieva

    2017-01-01

    The decreasing number of the Lithuanian residents has strong impact on the educational system: the number of pupils is decreasing, the schools are getting closed. School is considered to be the provider of educational services, so it is necessary to search, how to preserve and attract clients – pupils. The growing competition induces search for distinctiveness among the schools. According to the theory of generations of William Strauss and Neil Howe, now we have to educate representatives of ...

  18. Computing Science and Statistics: Volume 24. Graphics and Visualization

    Science.gov (United States)

    1993-03-20

    Models Mike West Institute of Statistics & Decision Sciences Duke University, Durham NC 27708, USA Abstract density estimation techniques. With an...ratio-of-uniforms halter, D. J., Best, N. G., McNeil, A. method. Statistics and Computing, 1, (in J., Sharples , L. D. and Kirby, A. J. press). (1992b...Dept of Act. Math & Stats Box 13040 SFA Riccarton Edinburgh, Scotland EH 14 4AS Nacognoches, TX 75962 mike @cara.ma.hw.ac.uk Allen McIntosh Michael T

  19. Atmospheric Measurements for Flight Test at NASAs Neil A. Armstrong Flight Research Center

    Science.gov (United States)

    Teets, Edward H.

    2016-01-01

    Information enclosed is to be shared with students of Atmospheric Sciences, Engineering and High School STEM programs. Information will show the relationship between atmospheric Sciences and aeronautical flight testing.

  20. Smith, Keynes and the monetary misconceptions of modern economics / James E O'Neil

    Index Scriptorium Estoniae

    O'Neil, James E

    2005-01-01

    Autor püüab ümber lükata müüti, mille kohaselt oleme jõudnud uue Võrdsuse Kultuuri lävele ning väidab, et kõiki asjaolusid arvesse võttes tuleks praegust aega nimetada pigem Võlakultuuri Ajastuks

  1. Decreased expression level of BER genes in Alzheimer's disease patients is not derivative of their DNA methylation status.

    Science.gov (United States)

    Sliwinska, Agnieszka; Sitarek, Przemysław; Toma, Monika; Czarny, Piotr; Synowiec, Ewelina; Krupa, Renata; Wigner, Paulina; Bialek, Katarzyna; Kwiatkowski, Dominik; Korycinska, Anna; Majsterek, Ireneusz; Szemraj, Janusz; Galecki, Piotr; Sliwinski, Tomasz

    2017-10-03

    Neurodegeneration in Alzheimer's disease can be caused by accumulation of oxidative DNA damage resulting from altered expression of genes involved in the base excision repair system (BER). Promoter methylation can affect the profile of BER genes expression. Decreased expression of BER genes was observed in the brains of AD patients. The aim of our study was to compare the expression and methylation profiles of six genes coding for proteins involved in BER, namely: hOGG1, APE1, MUTYH, NEIL1, PARP1 and XRCC1, in the peripheral blood cells of AD patients and healthy volunteers. The study consisted of 100 persons diagnosed with Alzheimer's disease according to DSM-IV criteria, and 110 healthy volunteers. DNA and total RNA were isolated from venous blood cells. Promoter methylation profiles were obtained by High Resolution Melting (HRM) analysis of bisulfide converted DNA samples. Real-time PCR with TaqMan probes was employed for gene expression analysis. APE1, hOGG1, MUTYH, PARP1 and NEIL1 were significantly (pgenes. The methylation status of promoters is not associated with downregulation of BER genes. Our results show that downregulation of BER genes detected in peripheral blood samples could reflect the changes occurring in the brain of patients with AD, and may be a useful biomarker of this disease. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Apollo 11 Earth Training Exercises

    Science.gov (United States)

    1969-01-01

    In preparation of the nation's first lunar landing mission, Apollo 11 crew members underwent training to practice activities they would be performing during the mission. In this photograph, taken at the Manned Spacecraft Center in Houston, Texas, an engineer, Bob Mason, donned in a space suit, goes through some of those training exercises on the mock lunar surface. He performed activites similar to those planned for astronauts Neil Armstrong and Edwin Aldrin during their moon walk. The Apollo 11 mission launched from the Kennedy Space Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  3. Quantum communication and other quantum information technologies

    CSIR Research Space (South Africa)

    Roux, FS

    2014-02-01

    Full Text Available -Podolsky-Rosen Albert Einstein Boris Podolsky Nathan Rosen Quantum mechanics: measurements on one particle dictate the state of the other particle. Spontaneous decay Unstable particle x p ∆x ∆p – p. 4/41 Parametric down conversion One incoming photon→ Two outgoing... ⊲ Decay of entanglement in turbulence — Theory — Numerical simulations — Experimental results – p. 2/41 Quantum mechanics Neils Bohr Paul Dirac Erwin Schroedinger Werner Heisenberg Lasers Computers Microelectronics Transistors – p. 3/41 Einstein...

  4. Eurovisioon, hõissa! White label : 4 Points of view : United Front, Ruckers, Gumbels, Testosteron. Kuula / DJ Pickney Tiger

    Index Scriptorium Estoniae

    DJ Pickney Tiger, pseud., 1970-

    2007-01-01

    Eurovisioonist kui sündmusest. Heliplaadist. Heliplaatidest: "Re:Jazz. Expansion", JJ Cale And Eric Clapton "The road to Escondido", Klaxons "Myths of the near future", Alexis On Fire "Crisis", Envy "Insomanic Doze", Rhythm Doctor "Tulgu Malakas!", Kasabian "Empire", Pogo Kreiner And Vienna Sound Orchestra "e-magic flute", Svjata Vatra " Svjata Vatra", Diskreetse Mango Trio "Prigadi-Pragadi", Neil Young And Crazy Horse "Live at the Fillmore 1970, March 6&7 1970", +44 "Whwn Your Heart Stops Beating", "The Family Values Tour 2006"

  5. Protest Movements and the Security Policy of the Federal Republic of Germany Since 1950.

    Science.gov (United States)

    1983-12-01

    to rearmament. The state of mind that framed a majority of the members, however, remained one of 33 semi- abstentionism where German labor remained on...I 0D A132 201 PROTEST MOVEMENTS AND THE SECURI Y POLICY 0 THE FEDERAL REPUBLIC OF GERMANY SINCE 1950( U) NAVAL\\ POSTGRADUATE SCHOOL MONEREY CA A N...1 THESIS PROTEST MOVEMENTS AND THE SECURITY POLICY OF THE FEDERAL REPUBLIC OF GERMANY SINCE 1950 by Arthur Neil Black 0. December 1983 C-) LIJ Thesis

  6. Klassiõpetaja peab särama / Ly Melesk, Kairis Kontus, Leida Talts, Viia Hang...[jt.] ; küsitles Anu Mõttus

    Index Scriptorium Estoniae

    2007-01-01

    Vestlusringis on Tallinna Kuristiku Gümnaasiumi klassiõpetajad Viia Hang ja Ly Melesk, Tallinna Ülikooli 5. kursuse üliõpilane ja Tallinna Lepistiku Lasteaed-Algkooli õpetaja Kairis Kontus, Tallinna Ülikooli algõpetuse õppetooli juhataja Leida Talts ning algõpetuse õppetooli pedagoogika ja algõpetuse metoodika õppejõud Mare Müürsepp. Kui hästi on Tallinna Ülikool ja tema eelkäijad suutnud algklassiõpetajaid ette valmistada ja mis neil igapäevatöös toime tulla aitab

  7. Reflective Efficacy

    Directory of Open Access Journals (Sweden)

    Carla Bagnoli

    2018-04-01

    Full Text Available The purpose of this paper is to highlight some difficulties of Neil Sinhababu’s Humean theory of agency, which depend on his radically reductivist approach, rather than to his Humean sympathies. The argument is that Sinhababu’s theory builds upon a critique of reflective agency which is based on equivocation and misunderstandings of the Kantian approach. Ultimately, the objection is that his reductivist view is unequipped to address the rclassical problems of rational deliberation and agential authority.

  8. Tööandja maine teadlik kujundamine loob edu / Kersti Hellerma

    Index Scriptorium Estoniae

    Hellerma, Kersti

    2007-01-01

    Kersti Hellerma magistritööst "Employer branding" selgub, et töötajad on sattunud otsustaja positsiooni, kus üks oluline töökoha valikukriteerium on tööandja maine ühiskonnas ehk kuvand, mille ettevõte on neile tööandjana jätnud. Vt. samas: Tööandja maineratas; Positiivne imago vähendab kulutusi; 10 atraktiivsemat tööandjat; Turundus ja finants populaarsed; Tehtav töö kõige olulisem; Riigifirmadel arenguruumi

  9. Geochemical Cruise Report SO226/2 RV Sonne Chatham Rise Expedition

    Science.gov (United States)

    2013-05-28

    Eingesetzte Geräte / Equiopment used Einsätze / tasks z.W zu Wasser / into water o.D. an Deck / on deck CTD 2 SL (max.) (maximale)Seillänge / max. rope...were also collected in the same locations for paleogeochemical analyses which will be completed by Helen Neil at National Institute of Water and...Figure 6. Pore water sampling using Rhizon samplers and distribution of samples in the lab van 11 Figure 7. Temperature and CH4 concentrations with

  10. Nanogel-crosslinked nanoparticles increase the inhibitory effects of W9 synthetic peptide on bone loss in a murine bone resorption model

    OpenAIRE

    Sato, Toshimi; Alles, Neil; Khan, Masud; Nagano, Kenichi; Takahashi, Mariko; Tamura, Yukihiko; Shimoda, Asako; Ohya, Keiichi; Akiyoshi, Kazunari; Aoki, Kazuhiro

    2015-01-01

    Toshimi Sato,1 Neil Alles,1,2 Masud Khan,1,3 Kenichi Nagano,1,4 Mariko Takahashi,1 Yukihiko Tamura,1 Asako Shimoda,5,6 Keiichi Ohya,1 Kazunari Akiyoshi,5,6 Kazuhiro Aoki1 1Department of Bio-Matrix (Pharmacology), Graduate School, Tokyo Medical and Dental University, Tokyo, Japan; 2Department of Biochemistry, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka; 3Department of Dental Pharmacology, City Dental College and Hospital, Dhaka, Bangladesh; 4Department of Oral Medicin...

  11. La mirada transgenérica

    Directory of Open Access Journals (Sweden)

    Judith Halberstam

    2004-01-01

    Full Text Available This text studies the construction and development of the transgender look in contemporary queer cinema, specifically: The Crying Game (Neil Jordan, 1992, Boys don't Cry (Kimberly Peirce, 2000 and By Hook or by Crook (Harry Dodge and Silas Howard, 2001. The analysis examines carefully the constitution of a meaningful materiality of the body through the gaze and the dialogue-confrontation between the transgender look and mainstream cinema's gaze, in its capability to regulate pleasures and sexual identities.

  12. The distribution of blood eosinophil levels in a Japanese COPD clinical trial database and in the rest of the world

    OpenAIRE

    Barnes, Neil; Ishii, Takeo; Hizawa, Nobuyuki; Midwinter, Dawn; James, Mark; Hilton, Emma; Jones, Paul W

    2018-01-01

    Neil Barnes,1,2 Takeo Ishii,3,4 Nobuyuki Hizawa,5 Dawn Midwinter,6 Mark James,3 Emma Hilton,1 Paul Jones1,71Respiratory Medicine Franchise, GlaxoSmithKline, Brentford, UK; 2William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, UK; 3Medical Affairs, GlaxoSmithKline K.K., Tokyo, Japan; 4Graduate School of Medicine, Nippon Medical School, Tokyo, Japan; 5Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan; 6Globa...

  13. Annual progress report

    International Nuclear Information System (INIS)

    Simon, A.

    1979-01-01

    The research topics covered include a study of the nonlinear behavior of the drift cyclotron loss-cone instability in mirror machines and a study of the longer time behavior of the nonlinear O'Neil trapped particle saturation. The saturation amplitude for a single dominant mode near the stability onset boundary was determined for the drift cyclotron loss-cone instability for a variety of mirror-like distributions. The results are in good agreement with computer simulation studies of Cohen and Maron

  14. Operations Events Census Report. Volume I, 1962 through 1966. Sanitized Version.

    Science.gov (United States)

    1991-04-01

    0664 BUSHNER, FRANCIS X. 3 016630 0603 BUSTAMANTE, RUDOLF , JR. 3 07573 0604 BUTLER, ARLIE G. 3 058856 0675 BUTLER, PAUL L. - 3 046756 0800 BUTTON...JAMES W. 3 052414 0636 STECKLER, ARNOLD 3 082459 0642 STEELE, ROBERT L. 3 030601 0601 STEINER , REECE W. 3 083143 0772 STEINMETZ, ARLIE H. 3 058641 0688...3 051802 0642 EISEN, NEIL T. 3 078378 0637 EKMAN, WIILARD 3 078340 0680 ELBRECHT, RUDOLF 3 087636 0746 ELIADES, JAMES 3 086818 0803 ELIAS, FREDRICK

  15. Declan FAHY (2015), The New Celebrity Scientists. Out of the Lab and into the Limelight

    OpenAIRE

    Fines-Neuschild, Mirjam

    2016-01-01

    The New Celebrity Scientists est le premier ouvrage de Declan Fahy. Il y fait le portrait de huit scientifiques en suivant leur parcours jusqu’à la célébrité et présente l’influence de leurs propos sur les politiques publiques. De ces huit scientifiques, trois sont physiciens : Stephen Hawking, Brian Greene et Neil de Grasse Tyson. Sont aussi présentés Richard Dawkins, biologiste, Steven Pinker, psychologue cognitiviste, Stephen Jay Gould, paléontologue, Susan Greenfield, pharmacologue, et Ja...

  16. Referendum Tšehhi Vabariigis / Helena Rögnerova

    Index Scriptorium Estoniae

    Rögnerova, Helena

    2003-01-01

    Ilmunud ka: Proceedings of the 9th international conference "Estonia and the European Union: Estonia on its way to a changing Europe" : October 30-November 1, 2002, Tallinn, Estonian National Library. - Tallinn, lk. 78-80. Tšehhi senati eurointegratsiooni komisjoni liikme arvates tuleks rahvani viia kaks sõnumit: EL on valmis looma ühesuguseid tingimusi nii praegustele kui uutele liikmetele ja EL-i liikmesriigina on tagatud neile traditsioonilised Euroopa väärtused nagu demokraatia, õigusriik, inimõiguste austamine ja vähemuste kaitsmine

  17. Alison Gregory Named Director of Library Services at Lycoming College

    Directory of Open Access Journals (Sweden)

    Alison S. Gregory

    2013-09-01

    Full Text Available Alison S. Gregory has been named Lycoming College’s Associate Dean and Director of Library Services at the John G. Snowden Memorial Library, according to an announcement by Dr. Phil Sprunger, Provost and Dean of the college. She began her duties July 1, having served the college since 2005 as Assistant Professor and Instructional Services Librarian and Coordinator of Information Literacy and Outreach. She is replacing Janet McNeil Hurlbert, who retired at the conclusion of the 2012-13 academic year.

  18. Teaching and learning in a digital age: myths of digital competence

    OpenAIRE

    Watling, Sue

    2014-01-01

    The human need to create, manage and control information and communication remains constant. It could be said books and Blackboard sites are different ways of doing the same thing and the gap between Gutenberg and Google is not as wide as it might first appear. In 370 BC Plato has Socrates bemoaning the introduction of writing as damaging to human memory. In 1981 Neil Postman predicted the rise of cable television would result in us all amusing ourselves to death. Back in 15th century Europe...

  19. “Free Water” as Commodity: The Paradoxes of Durban’s Water Service Transformations

    OpenAIRE

    Loftus, A

    2004-01-01

    In September 2002, an article in the Johannesburg Sunday Times declared a “torrent of praise for water man” Neil Macleod—the executive director of eThekwini Water Services (eTWS). The paper went on to extol his tremendous efforts and ingenuity “in turning around Durban’s water woes” (Horner 2002). eThekwini Municipality’s own publication, METRObeat, “saluted” Macleod and his department for having transformed the city’s crumbling water network and having ensured that “Durban leads the way in ...

  20. Rapid Translation of a Novel and Potent Vaccine in HER2+ Metastatic Breast Cancer Patients

    Science.gov (United States)

    2013-10-01

    Xia3, Neil Spector2,3, Larry S Barak4, Timothy M Clay5, Takuya Osada2, Erika Hamilton6, Kimberly Blackwell6, Amy C Hobeika2, Michael A Morse2,3, H Kim...Zhang L, Boehm MF, Fritz LC, Burrows FJ: A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 2003, 425:407...410. 13. Zhang H, Burrows F: Targeting multiple signal transduction pathways through inhibition of Hsp90. J Mol Med (Berl) 2004, 82:488-499. 14. Basso

  1. Former astronauts Schirra and Armstrong visit KSC for STS-83 launch

    Science.gov (United States)

    1997-01-01

    Among the many special NASA STS-83 launch guests who witnessed the liftoff of the Space Shuttle Columbia April 4 were Apollo 7 Commander Walter M. 'Wally' Schirra (left ) and Apollo l1 Commander Neil A. Armstrong. The two former astronauts are posing in front of the Apollo Command and Service Module in the Apollo/Saturn V Center at KSC. Columbia took off from Launch Pad 39A at 2:20:32 p.m. EST to begin the 16-day Microgravity Science Laboratory-1 (MSL-1) mission.

  2. Kinetic Study of Convective Drying of Blueberry Variety O’neil (Vaccinium corymbosum L. Estudio de la Cinética del Secado Convectivo de Arándano Variedad O’Neil (Vaccinium corymbosum L.

    Directory of Open Access Journals (Sweden)

    A Vega-Gálvez

    2009-06-01

    Full Text Available The aim of this research was to study and to model the drying kinetics of the blueberry Vaccinium corymbosum L. at three temperatures (60, 70 and 80 ºC with an airflow of 2.0 ± 0.2 m s-1. Modeling of the desorption isotherm was carried out with the GAB (Guggenheim, Anderson and de Boer equation, showing a good fit to experimental moisture data, giving as a result a monolayer moisture level of 0.084 g water g-1 dm. Newton, Henderson-Pabis, Page, Modified Page and Logarithmic mathematical models were applied in the study and in the modeling of the drying kinetics of this fruit. Kinetic parameters k of each model showed dependence on temperature, and were evaluated by an Arrhenius-type equation, with an activation energy of between 36.2 and 54.5 kJ mol-1. Logarithmic and Modified Page models gave the best fits for each drying curve, based on the statistical test determination coefficient, sum square error, root mean sum errors and Chi-square. In consequence, both models are excellent tools for estimating the drying time of this product.El objetivo de esta investigación fue estudiar y modelar la cinética de secado del arándano ( Vaccinium corymbosum L. a tres temperaturas (60, 70 y 80 ºC con un flujo de aire de 2,0 ± 0,2 m s-1. El modelado de la isoterma de desorción se llevó a cabo con la ecuación de GAB (Guggenheim, Anderson y de Boer, mostrando un buen ajuste sobre los datos experimentales de humedad, dando como resultado una humedad de la monocapa de 0,084 g de agua g-1 ms. Se aplicaron los modelos matemáticos de Newton, Henderson-Pabis, Page, Page modificado y Logarítmico para el modelado de la cinética de secado de esta fruta. Los parámetros cinéticos k de cada modelo presentaron dependencia con la temperatura, evaluadas por una ecuación de tipo Arrhenius, con una energía de activación entre 36,2-54,5 kJ mol-1. Los modelos Logarítmico y Page modificado obtuvieron el mejor ajuste para cada curva de secado, basado en las pruebas estadísticas como coeficiente de determinación, suma de errores cuadrados, raíz media de los errores cuadrados y Chi-cuadrado. En consecuencia, ambos modelos son excelentes herramientas para estimar el tiempo de secado de este producto.

  3. Bohr's Electron was Problematic for Einstein: String Theory Solved the Problem

    Science.gov (United States)

    Webb, William

    2013-04-01

    Neils Bohr's 1913 model of the hydrogen electron was problematic for Albert Einstein. Bohr's electron rotates with positive kinetic energies +K but has addition negative potential energies - 2K. The total net energy is thus always negative with value - K. Einstein's special relativity requires energies to be positive. There's a Bohr negative energy conflict with Einstein's positive energy requirement. The two men debated the problem. Both would have preferred a different electron model having only positive energies. Bohr and Einstein couldn't find such a model. But Murray Gell-Mann did! In the 1960's, Gell-Mann introduced his loop-shaped string-like electron. Now, analysis with string theory shows that the hydrogen electron is a loop of string-like material with a length equal to the circumference of the circular orbit it occupies. It rotates like a lariat around its centered proton. This loop-shape has no negative potential energies: only positive +K relativistic kinetic energies. Waves induced on loop-shaped electrons propagate their energy at a speed matching the tangential speed of rotation. With matching wave speed and only positive kinetic energies, this loop-shaped electron model is uniquely suited to be governed by the Einstein relativistic equation for total mass-energy. Its calculated photon emissions are all in excellent agreement with experimental data and, of course, in agreement with those -K calculations by Neils Bohr 100 years ago. Problem solved!

  4. Apollo 11 Astronauts In Prayer Within Quarantine Facility

    Science.gov (United States)

    1969-01-01

    The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via a Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. Aboard were Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. The recovery operation took place in the Pacific Ocean where Navy para-rescue men recovered the capsule housing the 3-man Apollo 11 crew. The crew was taken to safety aboard the USS Hornet, where they were quartered in a mobile quarantine facility. Shown here is the Apollo 11 crew inside the quarantine facility as prayer is offered by Lt. Commander John Pirrto, USS Hornet Chaplain accompanied by U.S. President Richard Nixon (front right). With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  5. La convergencia cultural a través de la ecología de medios Understanding Cultural Convergence through Media Ecology

    Directory of Open Access Journals (Sweden)

    Octavio Islas

    2009-10-01

    Full Text Available Antes de Internet cada medio de comunicación tenía funciones y mercados perfectamente definidos. Sin embargo, a consecuencia del formidable desarrollo de Internet y de las comunicaciones digitales, el mismo contenido hoy puede circular a través de distintos medios de comunicación. Esa es la convergencia cultural. El relato transmediático anticipa el advenimiento de nuevos mercados de consumo cultural. Con base en la ecología de medios y particularmente considerando las tesis de Marshall McLuhan, Neil Postman y Henry Jenkins, es analizada la convergencia cultural como complejo ambiente comunicativo. La convergencia cultural modifica los procedimientos de operación de las industrias mediáticas. Los cambios más significativos, sin embargo, se presentan en las comunidades de conocimiento. Before the Internet, the different media had specifically defined functions and markets. However, since the emergence of the Internet and digital communication, the same content can be found right across the media; this is known as cultural convergence. This media crossing anticipates the coming of new markets of cultural consumption. Based on media ecology, with specific reference to the thesis developed by Marshall McLuhan, Neil Postman, and Henry Jenkins, cultural convergence is studied as a complex communication environment. Cultural convergence modifies the operative procedures of media industries. However, the most significant changes can be found within the knowledge communities.

  6. Annual progress report

    International Nuclear Information System (INIS)

    Simon, A.

    1980-01-01

    Research efforts were concentrated on two main topics. One was to obtain a fit between single-mode nonlinear saturation theory and experimental observations on the PR-6 mirror device. A model of this experiment yields good agreement between predictions of the time variation of the fluctuating potential level, the floating potential, the mode wavelength and mode frequency, and observations. The second topic concerned single-mode Landau damping. The previous results of O-Neil-Morales were confirmed, but in much simpler form with no multiple sums. No longer-time corrections of any significant size were uncovered

  7. Advertisements impact the physiological efficacy of a branded drug

    Science.gov (United States)

    Kamenica, Emir; Naclerio, Robert; Malani, Anup

    2013-01-01

    We conducted randomized clinical trials to examine the impact of direct-to-consumer advertisements on the efficacy of a branded drug. We compared the objectively measured, physiological effect of Claritin (Merck & Co.), a leading antihistamine medication, across subjects randomized to watch a movie spliced with advertisements for Claritin or advertisements for Zyrtec (McNeil), a competitor antihistamine. Among subjects who test negative for common allergies, exposure to Claritin advertisements rather than Zyrtec advertisements increases the efficacy of Claritin. We conclude that branded drugs can interact with exposure to television advertisements. PMID:23878212

  8. Palabras sobre la palabra

    Directory of Open Access Journals (Sweden)

    Pedro Acosta

    1979-04-01

    Full Text Available En el instante mismo del 20 de julio de 1963 en que Neil Armstrong marcó la huella del hombre en el suelo de la luna, arreciaron las lamentaciones  por la agonía de la literatura. O, si se quiere, de las letras, para el caso de querer precisar en lo escrito aquello que por sí es un infinito de creación, sutileza y adivinación, y por lo tanto imposible de amenguar con la limitación de definiciones exáctas.

  9. Lugemise algõpetusest nii ja naa / Mare Müürsepp

    Index Scriptorium Estoniae

    Müürsepp, Mare

    2001-01-01

    1998-2000.a. läbi viidud küsitlusest 185 õpetaja seas, kes on töötanud 1. ja 2. klassis. Uuringu eesmärgiks oli välja selgitada maa-, väikelinna- ja suurlinna koolide algklassiõpetajate seisukohti lugemaõpetamises, kuidas õpetajad arvestavad õpilase enesehinnanguga, mida peavad tähtsaks õpikeskkonna loomisel, milliseid tegevusi eelistavad õpilastele pakkuda, millised eesmärgid on neil lugemisõpetuses. Uuringu tulemustes toodi välja erinevused maa-, väikelinna- ja suurlinna koolide algklassiõpetajate ettevalmistuses ja õpetamismeetodites

  10. The Oklo reactor

    International Nuclear Information System (INIS)

    McNeil, Russell

    1986-01-01

    The construction of a reactor, capable of producing a controlled nuclear chain reaction, has been one of the most complex achievements of modern science. That a similar reaction might take place in nature did not play a role in the thinking of the nuclear scientists responsible for it. Yet, 14 years ago, French scientists discovered that just such a phenomenon apparently occurred in western Africa almost 2 billion years ago. In this article Russell McNeil describes this fascinating curiosity and a recent attempt to model it mathematically

  11. Wavefront reconstruction by modal decomposition

    CSIR Research Space (South Africa)

    Schulze, C

    2012-08-01

    Full Text Available National Laser Centre, P.O. Box 395, Pretoria, South Africa 3Now with the Max Planck Institute for the Science of Light, Guenther-Scharowsky-Str. 1, 91058 Erlangen, Germany 4School of Physics, University of KwaZulu-Natal, Private Bag X54001, Durban 4000.... References and links 1. F. Roddier, M. Se?chaud, G. Rousset, P.-Y. Madec, M. Northcott, J.-L. Beuzit, F. Rigaut, J. Beckers, D. Sandler, P. Le?na, and O. Lai, Adaptive Optics in Astronomy (Cambridge, 1999). 2. M. A. A. Neil, R. Jukaitis, M. J. Booth, T...

  12. The Evolving Science of Patient and Family Engagement: An Interview With Dr Karen Drenkard.

    Science.gov (United States)

    Reid-Ponte, Patricia

    2018-02-01

    Patient- and family-centered care is a central tenet of nursing practice. This concept has evolved to include patient partnerships, patient engagement, and patient activation. This column differentiates these concepts and describes the core principles embedded in the overriding intention of ensuring that patients (and their families or significant others) are orchestrators of their health and their care plans. In this interview, Karen Drenkard, PhD, RN, FAAN, NEA-BC, CNO, of the GetWellNetwork, discusses work by the O'Neil Center as a leader in this area.

  13. Outside the margin. Metaphors of disability and integration in the recent literature for children.

    Directory of Open Access Journals (Sweden)

    William Grandi

    2012-06-01

    Full Text Available The article investigates recent Children’s Literature, in order to find out metaphors and references about disabled people. Documentation on this issue is so abundant that only the most considerable tales and writers was analyzed: for instance, Neil Gaiman, Roald Dahl, Silvana Gandolfi and many other writers dedicated some of their books to characters with physical disabilities, dyslexia, autism. This research shows that Children’s Literature can enable children and grown-up people not only to know disabilities, but also to start up social integration of disabled person.

  14. Telecast of Astronauts Armstrong and Aldrin by the Lunar Module

    Science.gov (United States)

    1969-01-01

    Astronauts Neil A. Armstrong (in center) commander; and Edwin E. Aldrin Jr. (on right), lunar module pilot, are seen standing near their Lunar Module in this black and white reproduction taken from a telecast by the Apollo 11 lunar surface television camera during the Apollo 11 extravehicular activity. This picture was made from a televised image received at the Deep Space Network tracking station at Goldstone, California. President Richard M. Nixon had just spoken to the two astronauts by radio and Aldrin, a colonel in the U.S. Air Force, is saluting the president.

  15. Test pilots 1962 - Armstrong, Walker, Dana, Peterson, McKay, Thompson, Butchart

    Science.gov (United States)

    1962-01-01

    The research pilots at what in 1962 was called the Flight Research Center standing in front of the X-1E. They are (left to right) Neil Armstrong, Joe Walker, Bill Dana, Bruce Peterson, Jack McKay, Milt Thompson, and Stan Butchart. of the group, Armstrong, Walker, Dana, McKay and Thompson all flew the X-15. Bruce Peterson flew the M2-F2 and HL-10 lifting bodies, while Stan Butchart was the B-29 drop plane pilot for many of the D-558-II and X-1 series research aircraft.

  16. U.S. Naval Strategy in the 1970s. Selected Documents

    Science.gov (United States)

    2007-09-01

    Gaffney (CNA); Mr. Mike Gerson (CNA); Commander Neil Golightly, USNR (Ret.); Ms. Gia Harrington; Captain Robby Harris, USN (Ret.); Mr. Richard Haver...ships, beginning with the USS Blue Ridge , laid down in 1967 and commissioned in November 1970. The lead ship of a new class of nuclear-powered...use of force against the shore 120 U . S . N A V A L S T R A T E G Y I N T H E 1 9 7 0 S 1 5 3 uses of naval forces 106 USS Blue Ridge xiii USS Los

  17. MegaFoni-diplomaatia : oligarh sõdib Putini liitlasega / Stephen Fidler, Arkady Ostrovsky, Neil Buckley

    Index Scriptorium Estoniae

    Fidler, Stephen

    2006-01-01

    Vene firma Alfa väitel kasutatakse firmat Ipoc rahapesuks ja selle telekomiinvesteeringute tegelik omanik on telekommunikatsiooniminister Leonid Reiman. Reimani väitel ei ole talle kunagi kuulunud Ipoci osakuid, ta pole kunagi olnud selle otsene või kaudne omanik. Ipoc on uurimise all Bermudal

  18. Neil Hayes, M.D., M.P.H., Explains TCGA Findings on GBM Subtypes - TCGA

    Science.gov (United States)

    New findings by researchers at UNC Lineberger Comprehensive Cancer Center suggest that the most common form of malignant brain cancer in adults, glioblastoma multiforme (GBM), is probably not a single disease but a set of diseases, each with a distinct underlying molecular disease process. The study was published by Cell Press in the January issue of the journal Cancer Cell and the researchers are part of the The Cancer Genome Atlas.

  19. Isamaa ja Res Publica liit tõotab neile kõrget kohta edetabelis / Rasmus Kagge

    Index Scriptorium Estoniae

    Kagge, Rasmus, 1977-

    2006-01-01

    Ilmunud ka: Postimees : na russkom jazõke 10. apr. lk. 7. TNS Emori märtsikuu erakondade populaarsusuuringu tulemused näitavad, et Res Publicaga liituda otsustanud Isamaaliit on tõusnud poliitedetabelis kolmandale kohale. Res Publica reiting on endiselt madal, edetabelit juhib Keskerakond. Diagrammid: Isamaaliit kogub toetajaid tõusvas tempos. Vt. samas: Ühendpartei Eesti Eest! otsib endale uut nime

  20. Optical Follow-up of Gravitational-wave Events with Las Cumbres Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Arcavi, Iair; McCully, Curtis; Hosseinzadeh, Griffin; Howell, D. Andrew; Vasylyev, Sergiy [Department of Physics, University of California, Santa Barbara, CA 93106-9530 (United States); Poznanski, Dovi; Zaltzman, Michael; Maoz, Dan [Raymond and Beverly Sackler School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978 (Israel); Singer, Leo [Joint Space-Science Institute, University of Maryland, College Park, MD 20742 (United States); Valenti, Stefano [Department of Physics, University of California, 1 Shields Avenue, Davis, CA 95616-5270 (United States); Kasen, Daniel [Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720-8169 (United States); Barnes, Jennifer [Columbia Astrophysics Laboratory, Columbia University, New York, NY, 10027 (United States); Piran, Tsvi [Racah Institute of Physics, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel); Fong, Wen-fai, E-mail: arcavi@ucsb.edu [CIERA and Department of Physics and Astronomy, Northwestern University 2145 Sheridan Road, Evanston, IL 60208 (United States)

    2017-10-20

    We present an implementation of the Gehrels et al. galaxy-targeted strategy for gravitational-wave (GW) follow-up using the Las Cumbres Observatory global network of telescopes. We use the Galaxy List for the Advanced Detector Era (GLADE) galaxy catalog, which we show is complete (with respect to a Schechter function) out to ∼300 Mpc for galaxies brighter than the median Schechter function galaxy luminosity. We use a prioritization algorithm to select the galaxies with the highest chance of containing the counterpart given their luminosity, their position, and their distance relative to a GW localization, and in which we are most likely to detect a counterpart given its expected brightness compared to the limiting magnitude of our telescopes. This algorithm can be easily adapted to any expected transient parameters and telescopes. We implemented this strategy during the second Advanced Detector Observing Run (O2) and followed the black hole merger GW170814 and the neutron star merger GW170817. For the latter, we identified an optical kilonova/macronova counterpart thanks to our algorithm selecting the correct host galaxy fifth in its ranked list among the 182 galaxies we identified in the Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo localization. This also allowed us to obtain some of the earliest observations of the first optical transient ever triggered by a GW detection (as presented in a companion paper).

  1. Optical Follow-up of Gravitational-wave Events with Las Cumbres Observatory

    Science.gov (United States)

    Arcavi, Iair; McCully, Curtis; Hosseinzadeh, Griffin; Howell, D. Andrew; Vasylyev, Sergiy; Poznanski, Dovi; Zaltzman, Michael; Maoz, Dan; Singer, Leo; Valenti, Stefano; Kasen, Daniel; Barnes, Jennifer; Piran, Tsvi; Fong, Wen-fai

    2017-10-01

    We present an implementation of the Gehrels et al. galaxy-targeted strategy for gravitational-wave (GW) follow-up using the Las Cumbres Observatory global network of telescopes. We use the Galaxy List for the Advanced Detector Era (GLADE) galaxy catalog, which we show is complete (with respect to a Schechter function) out to ˜300 Mpc for galaxies brighter than the median Schechter function galaxy luminosity. We use a prioritization algorithm to select the galaxies with the highest chance of containing the counterpart given their luminosity, their position, and their distance relative to a GW localization, and in which we are most likely to detect a counterpart given its expected brightness compared to the limiting magnitude of our telescopes. This algorithm can be easily adapted to any expected transient parameters and telescopes. We implemented this strategy during the second Advanced Detector Observing Run (O2) and followed the black hole merger GW170814 and the neutron star merger GW170817. For the latter, we identified an optical kilonova/macronova counterpart thanks to our algorithm selecting the correct host galaxy fifth in its ranked list among the 182 galaxies we identified in the Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo localization. This also allowed us to obtain some of the earliest observations of the first optical transient ever triggered by a GW detection (as presented in a companion paper).

  2. Transport in a toroidally confined pure electron plasma

    International Nuclear Information System (INIS)

    Crooks, S.M.; ONeil, T.M.

    1996-01-01

    O close-quote Neil and Smith [T.M. O close-quote Neil and R.A. Smith, Phys. Plasmas 1, 8 (1994)] have argued that a pure electron plasma can be confined stably in a toroidal magnetic field configuration. This paper shows that the toroidal curvature of the magnetic field of necessity causes slow cross-field transport. The transport mechanism is similar to magnetic pumping and may be understood by considering a single flux tube of plasma. As the flux tube of plasma undergoes poloidal ExB drift rotation about the center of the plasma, the length of the flux tube and the magnetic field strength within the flux tube oscillate, and this produces corresponding oscillations in T parallel and T perpendicular . The collisional relaxation of T parallel toward T perpendicular produces a slow dissipation of electrostatic energy into heat and a consequent expansion (cross-field transport) of the plasma. In the limit where the cross section of the plasma is nearly circular the radial particle flux is given by Γ r =1/2ν perpendicular,parallel T(r/ρ 0 ) 2 n/(-e∂Φ/∂r), where ν perpendicular,parallel is the collisional equipartition rate, ρ 0 is the major radius at the center of the plasma, and r is the minor radius measured from the center of the plasma. The transport flux is first calculated using this simple physical picture and then is calculated by solving the drift-kinetic Boltzmann equation. This latter calculation is not limited to a plasma with a circular cross section. copyright 1996 American Institute of Physics

  3. Oxidatively-induced DNA damage and base excision repair in euthymic patients with bipolar disorder.

    Science.gov (United States)

    Ceylan, Deniz; Tuna, Gamze; Kirkali, Güldal; Tunca, Zeliha; Can, Güneş; Arat, Hidayet Ece; Kant, Melis; Dizdaroglu, Miral; Özerdem, Ayşegül

    2018-05-01

    Oxidatively-induced DNA damage has previously been associated with bipolar disorder. More recently, impairments in DNA repair mechanisms have also been reported. We aimed to investigate oxidatively-induced DNA lesions and expression of DNA glycosylases involved in base excision repair in euthymic patients with bipolar disorder compared to healthy individuals. DNA base lesions including both base and nucleoside modifications were measured using gas chromatography-tandem mass spectrometry and liquid chromatography-tandem mass spectrometry with isotope-dilution in DNA samples isolated from leukocytes of euthymic patients with bipolar disorder (n = 32) and healthy individuals (n = 51). The expression of DNA repair enzymes OGG1 and NEIL1 were measured using quantitative real-time polymerase chain reaction. The levels of malondialdehyde were measured using high performance liquid chromatography. Seven DNA base lesions in DNA of leukocytes of patients and healthy individuals were identified and quantified. Three of them had significantly elevated levels in bipolar patients when compared to healthy individuals. No elevation of lipid peroxidation marker malondialdehyde was observed. The level of OGG1 expression was significantly reduced in bipolar patients compared to healthy individuals, whereas the two groups exhibited similar levels of NEIL1 expression. Our results suggest that oxidatively-induced DNA damage occurs and base excision repair capacity may be decreased in bipolar patients when compared to healthy individuals. Measurement of oxidatively-induced DNA base lesions and the expression of DNA repair enzymes may be of great importance for large scale basic research and clinical studies of bipolar disorder. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Pre-steady-state fluorescence analysis of damaged DNA transfer from human DNA glycosylases to AP endonuclease APE1.

    Science.gov (United States)

    Kuznetsova, Alexandra A; Kuznetsov, Nikita A; Ishchenko, Alexander A; Saparbaev, Murat K; Fedorova, Olga S

    2014-10-01

    DNA glycosylases remove the modified, damaged or mismatched bases from the DNA by hydrolyzing the N-glycosidic bonds. Some enzymes can further catalyze the incision of a resulting abasic (apurinic/apyrimidinic, AP) site through β- or β,δ-elimination mechanisms. In most cases, the incision reaction of the AP-site is catalyzed by special enzymes called AP-endonucleases. Here, we report the kinetic analysis of the mechanisms of modified DNA transfer from some DNA glycosylases to the AP endonuclease, APE1. The modified DNA contained the tetrahydrofurane residue (F), the analogue of the AP-site. DNA glycosylases AAG, OGG1, NEIL1, MBD4(cat) and UNG from different structural superfamilies were used. We found that all DNA glycosylases may utilise direct protein-protein interactions in the transient ternary complex for the transfer of the AP-containing DNA strand to APE1. We hypothesize a fast "flip-flop" exchange mechanism of damaged and undamaged DNA strands within this complex for monofunctional DNA glycosylases like MBD4(cat), AAG and UNG. Bifunctional DNA glycosylase NEIL1 creates tightly specific complex with DNA containing F-site thereby efficiently competing with APE1. Whereas APE1 fast displaces other bifunctional DNA glycosylase OGG1 on F-site thereby induces its shifts to undamaged DNA regions. Kinetic analysis of the transfer of DNA between human DNA glycosylases and APE1 allows us to elucidate the critical step in the base excision repair pathway. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. IEA agreement on the production and utilization of hydrogen: 2000 annual report

    International Nuclear Information System (INIS)

    Elam, Carolyn C.

    2001-01-01

    The 2000 annual report of the IEA Hydrogen Agreement contains an overview of the agreement, including its guiding principles, latest strategic plan, and a report from the Chairman, Mr. Neil P. Rossmeissl, U.S. Department of Energy. Overviews of the National Hydrogen Programs of nine member countries are given: Canada, Japan, Lithuania, the Netherlands, Norway, Spain, Sweden, Switzerland, and the United States. Task updates are provided on the following annexes: Annex 12 - Metal Hydrides and Carbon for Hydrogen Storage, Annex 13 - Design and Optimization of Integrated Systems, Annex 14 - Photoelectrolytic Production of Hydrogen, and, Annex 15 - Photobiological Production of Hydrogen

  6. War casualties on the home front

    Energy Technology Data Exchange (ETDEWEB)

    Brenda J. Flinn

    2005-11-01

    On May 12, 1942, at Christopher coal mine No. 3 in Osage, West Virginia, a continent away from the frontlines of World War II, Superintendent Ed O'Neil saw the mine ventilation fan suddenly run backwards, propelled by a strong gust of air that tore the belt off the huge blower. The second shift mantrip of 115 coal miners, traversing the drift mouth for the 3:00 p.m. shift, ground to an uneasy halt. The article recounts the tragic consequences of this incident. It also tells of other events affecting coal miners during World War I and World War II.

  7. IEA agreement on the production and utilization of hydrogen: 2000 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Elam, Carolyn C. [National Renewable Energy Lab., Golden, CO (US)] (ed.)

    2001-12-01

    The 2000 annual report of the IEA Hydrogen Agreement contains an overview of the agreement, including its guiding principles, latest strategic plan, and a report from the Chairman, Mr. Neil P. Rossmeissl, U.S. Department of Energy. Overviews of the National Hydrogen Programs of nine member countries are given: Canada, Japan, Lithuania, the Netherlands, Norway, Spain, Sweden, Switzerland, and the United States. Task updates are provided on the following annexes: Annex 12 - Metal Hydrides and Carbon for Hydrogen Storage, Annex 13 - Design and Optimization of Integrated Systems, Annex 14 - Photoelectrolytic Production of Hydrogen, and, Annex 15 - Photobiological Production of Hydrogen.

  8. Introduction: Mirrors of Passing

    DEFF Research Database (Denmark)

    Seebach, Sophie Hooge; Willerslev, Rane

    How is death, time, and materiality interconnected? How to approach an understanding of the world of the dead? In this introduction, we seek to understand how the experience of material decay, of the death of those around us, makes us aware of the passing of time. Through the literary lens of Neil...... Gaiman’s The Graveyard Book, we explore how the world of the dead and the world of the living can intersect; how time and materiality shifts and changes depending on who experiences it. These revelations, based on fiction, provide a mirror through which the reader can experience the varied chapters...

  9. Using SPSS for Windows and Macintosh analyzing and understanding data

    CERN Document Server

    Green, Samuel B

    2012-01-01

    The development of easy-to-use statistical software like SPSS has changed the way statistics is being taught and learned. Students can make transformations of variables, create graphs of distributions of variables, and select among statistical analyses all at the click of a button. However, even with these advancements, students sometimes still find statistics to be an arduous task. They continue to be faced with many potential obstacles and they might feel overwhelmed and stressed rather than challenged and excited about the potential for mastering these important skills. Samuel Green and Neil Salkind have written a text to specifically address these issues.

  10. Eakatele suurem kaal omavalitsustes / Tunne Kelam

    Index Scriptorium Estoniae

    Kelam, Tunne, 1936-

    2004-01-01

    Ilmunud ka: Virumaa Teataja, 16. apr. 2004, lk. 7; Põhjarannik, 16. apr. 2004, lk. 2; Severnoje Poberezhje, 16. apr. 2004, lk. 2; Hiiumaa, 17. apr. 2004, lk. 2; Koit, 20. apr. 2004, lk. 6; Pärnu Postimees, 21. apr. 2004, lk. 15; Vali Uudised, 21. apr. 2004, lk. 2; Meie Maa, 21. apr. 2004, lk. 2; Videvik, 22. apr. 2004, lk. 3; Sakala, 11. mai 2004, lk. 2. Autori arvates tuleks lõpetada vabatahtliku pensionikindlustuse rahastamine esimese samba arvelt, samuti tuleb enam kaasata eakaid inimesi otsuste tegemise protsessi ja tagada neile suuremad võimalused kohaliku elu mõjutamiseks

  11. Mobile Design Pattern Gallery UI Patterns for Mobile Applications

    CERN Document Server

    Neil, Theresa

    2012-01-01

    When you're under pressure to produce a well designed, easy-to-navigate mobile app, there's no time to reinvent the wheel. This concise book provides a handy reference to 70 mobile app design patterns, illustrated by more than 400 screenshots from current iOS, Android, BlackBerry, WebOS, Windows Mobile, and Symbian apps. User experience professional Theresa Neil (Designing Web Interfaces) walks you through design patterns in 10 separate categories, including anti-patterns. Whether you're designing a simple iPhone application or one that's meant to work for every popular mobile OS on the mark

  12. Talking about Life

    Science.gov (United States)

    Impey, Chris

    2010-08-01

    Preface; Part I. Introduction Timothy Ferris, Iris Fry, Steven Dick, Ann Druyan, Pinky Nelson, Neil Tyson, Steve Benner and William Bains; Part II. Earth Roger Buick, Lynn Rothschild, John Baross, Joe Kirschvink, Andrew Knoll, Simon Conway Morris, Roger Hanlon and Lori Marino; Part III. Solar System Chris McKay, David Grinspoon, Jonathan Lunine, Carolyn Porco, Laurie Leshin, Guy Consolmagno and Peter Smith; Part IV. Exoplanets Alan Boss, Geoff Marcy, Debra Fischer, Sara Seager, David Charbonneau and Vikki Meadows; Part V. Frontiers Jill Tarter, Seth Shostak, Ray Kurzweil, Nick Bostrom, Paul Davies, Martin Rees, Ben Bova and Jennifer Michael Hecht; Reading list; Glossary; Index.

  13. Dynamic regulation of cerebral DNA repair genes by psychological stress

    DEFF Research Database (Denmark)

    Forsberg, Kristin; Aalling, Nadia; Wörtwein, Gitta

    2015-01-01

    Neuronal genotoxic insults from oxidative stress constitute a putative molecular link between stress and depression on the one hand, and cognitive dysfunction and dementia risk on the other. Oxidative modifications to DNA are repaired by specific enzymes; a process that plays a critical role...... restraint stress (6h/day) or daily handling (controls), and sacrificed after 1, 7 or 21 stress sessions. The mRNA expression of seven genes (Ogg1, Ape1, Ung1, Neil1, Xrcc1, Ercc1, Nudt1) involved in the repair of oxidatively damaged DNA was determined by quantitative real time polymerase chain reaction...

  14. Apollo 11 crewmembers participate in water egress training in Gulf of Mexico

    Science.gov (United States)

    1969-01-01

    The third member of the prime crew of the Apollo 11 lunar landing mission egresses Apollo Boilerplate 1102 during water egress training in the Gulf of Mexico. The other two crewmen are in raft. Taking part in the training were Astronauts Neil A. Armstrong, commander; Michael Collins, command module pilot; and Edwin E. Aldrin Jr., lunar module pilot. The three crewmen practiced donning and wearing biological isolation garments (B.I.G.) as a part of the exercise. The Manned Spacecraft Center (MSC) swimmer standing up, who assisted in the training, is also wearing a B.I.G.

  15. Bloody eroticism in interview with the vampire

    OpenAIRE

    Lima, Dante Luiz

    2007-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-graduação em Letras/Inglês e Literatura Correspondente Este estudo tem o intuito de investigar como textos literários são adaptados para o cinema. Esta investigação foi feita usando-se o romance Entrevista com o Vampiro (1976) de Anne O´Brien Rice e sua adaptação fílmica (1994) dirigida por Neil Jordan. O aspecto principal do romance e do filme analisados durante a pesquisa f...

  16. New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways.

    Directory of Open Access Journals (Sweden)

    Modesto Redrejo-Rodríguez

    Full Text Available BACKGROUND: Oxidative damage to DNA, if not repaired, can be both miscoding and blocking. These genetic alterations can lead to mutations and/or cell death, which in turn cause cancer and aging. Oxidized DNA bases are substrates for two overlapping repair pathways: base excision (BER and nucleotide incision repair (NIR. Hydantoin derivatives such as 5-hydroxyhydantoin (5OH-Hyd and 5-methyl-5-hydroxyhydantoin (5OH-5Me-Hyd, major products of cytosine and thymine oxidative degradation pathways, respectively, have been detected in cancer cells and ancient DNA. Hydantoins are blocking lesions for DNA polymerases and excised by bacterial and yeast DNA glycosylases in the BER pathway. However little is known about repair of pyrimidine-derived hydantoins in human cells. METHODOLOGY/PRINCIPAL FINDINGS: Here, using both denaturing PAGE and MALDI-TOF MS analyses we report that the bacterial, yeast and human AP endonucleases can incise duplex DNA 5' next to 5OH-Hyd and 5OH-5Me-Hyd thus initiating the NIR pathway. We have fully reconstituted the NIR pathway for these lesions in vitro using purified human proteins. Depletion of Nfo in E. coli and APE1 in HeLa cells abolishes the NIR activity in cell-free extracts. Importantly, a number of redundant DNA glycosylase activities can excise hydantoin residues, including human NTH1, NEIL1 and NEIL2 and the former protein being a major DNA glycosylase activity in HeLa cells extracts. CONCLUSIONS/SIGNIFICANCE: This study demonstrates that both BER and NIR pathways can compete and/or back-up each other to remove hydantoin DNA lesions in vivo.

  17. A Summary of the Rendezvous, Proximity Operations, Docking, and Undocking (RPODU) Lessons Learned from the Defense Advanced Research Project Agency (DARPA) Orbital Express (OE) Demonstration System Mission

    Science.gov (United States)

    Dennehy, Cornelius J.; Carpenter, James R.

    2011-01-01

    The Guidance, Navigation, and Control (GN&C) Technical Discipline Team (TDT) sponsored Dr. J. Russell Carpenter, a Navigation and Rendezvous Subject Matter Expert (SME) from NASA's Goddard Space Flight Center (GSFC), to provide support to the Defense Advanced Research Project Agency (DARPA) Orbital Express (OE) rendezvous and docking flight test that was conducted in 2007. When that DARPA OE mission was completed, Mr. Neil Dennehy, NASA Technical Fellow for GN&C, requested Dr. Carpenter document his findings (lessons learned) and recommendations for future rendezvous missions resulting from his OE support experience. This report captures lessons specifically from anomalies that occurred during one of OE's unmated operations.

  18. "Hello!" from Crosby and Nash

    CERN Multimedia

    CERN Bulletin

    2015-01-01

    On Tuesday, 29 September, American musicians David Crosby and Graham Nash visited CERN. They also recorded a video message, commenting on their visit and sending their greetings and thanks to CERN's people.   (Video: Christoph M. Madsen/CERN.) David Crosby, Graham Nash, and Stephen Stills have played together for over 30 years in the Crosby, Stills and Nash folk rock band. Originally, together with Neil Young, they were all members of the Crosby, Stills, Nash and Young band, having played at the iconic Woodstock Festival and produced many legendary songs such as Teach Your Children, Judy Blue Eyes, Our House and Marrakech Express. ​

  19. Kohaliku arengu võti on kohapeal / Rein Aidma

    Index Scriptorium Estoniae

    Aidma, Rein, 1950-

    2004-01-01

    Ilmunud ka: Pärnu Postimees, 15. okt. 2004, lk. 15; Meie Maa, 15. okt. 2004, lk. 2; Põhjarannik, 15. okt. 2004, lk. 2; Severnoje Poberezhje, 15. okt. 2004, lk. 2; Võrumaa Teataja, 16. okt. 2004, lk. 2; Koit, 16. okt. 2004, lk. 6; Nädaline, 16. okt. 2004, lk. 4; Hiiu Leht, 19. okt. 2004, lk. 2; Harjumaa, 19. okt. 2004, lk. 2; Sakala, 22. okt. 2004, lk. 2; Sõnumitooja, 22. okt. 2004, lk. 2; Virumaa Nädalaleht, 26. nov. 2004, lk. 5. Riigikogu maaelukomisjoni liige pöördub kohalike omavalitsuste poole soovitades neil säilitada koostöötahet ja mõistvat suhtumist kohalike probleemide lahendamisel

  20. Modeling of Focused Acoustic Field of a Concave Multi-annular Phased Array Using Spheroidal Beam Equation

    Science.gov (United States)

    Yu, Li-Li; Shou, Wen-De; Hui, Chun

    2012-02-01

    A theoretical model of focused acoustic field for a multi-annular phased array on concave spherical surface is proposed. In this model, the source boundary conditions of the spheroidal beam equation (SBE) for multi-annular phased elements are studied. Acoustic field calculated by the dynamic focusing model of SBE is compared with numerical results of the O'Neil and Khokhlov—Zabolotskaya—Kuznetsov (KZK) model, respectively. Axial dynamic focusing and the harmonic effects are presented. The results demonstrate that the dynamic focusing model of SBE is good valid for a concave multi-annular phased array with a large aperture angle in the linear or nonlinear field.

  1. A Reappraisal of Combined 147,146Sm-143,142Nd Systematics for Eoarchean Rocks from the Nuvvuagittuq Supracrustal Belt, northern Québec (Canada)

    Science.gov (United States)

    Roth, A. S.; Touboul, M.; Bourdon, B.; Kleine, T.; Mojzsis, S. J.

    2009-12-01

    Coupled 147,146Sm-143,142Nd systematics represent a powerful means to unravel the scale and tempo of the earliest differentiation of the silicate Earth. While a signature of early mantle depletion has been preserved as positive 142Nd anomalies in Eoarchean crustal rocks from the Itsaq Gneiss Complex of southern West Greenland (Harper and Jacobsen 1992, Caro et al. 2006, Bennett et al. 2007) and the Narryer Gneiss Complex in Western Australia (Bennett et al. 2007), evidence for complementary early-enriched reservoirs is sparse. The first such evidence was recently reported by O’Neil et al. (2008) in the form of negative 142Nd anomalies in pre-3750 Ma rocks from the Nuvvuagittuq supracrustal belt (NSB) in northern Québec (e.g. Cates and Mojzsis 2007). Discovery of such anomalies in separate Eoarchean terranes would offer profound insight into the early history of the silicate Earth viz. our understanding of the degree of chemical heterogeneity in the primitive Earth's crust-mantle system. Such heterogeneities may have been preserved for billions of years under the lithospheric roots of cratons (Upadhyay et al. 2009). O'Neill et al. (2008) reported 142Nd/144Nd ratios lower than the terrestrial standard for some NSB rock types (ɛ142Nd = -0.07 to -0.15 that are correlated with the Sm/Nd ratios of their sources). Based on this correlation the authors derived an age of ~4.28 Ga for a cummingtonite+biotite±garnet amphibolite unit that may represent some of the oldest preserved crust on Earth. Others have however questioned this conclusion (Andreasen and Sharma, 2009) and argued instead that the Hadean age of this unit is based on a correlation between rocks that are probably not co-genetic, and that the observed negative 142Nd anomalies may rather be the result of corrections for mass fractionation during mass spectrometric analyses. The importance of identifying early enriched reservoirs in Earth motivated our study. Here we report our first Nd isotope data for rocks

  2. The Sleeper and the Spindle de Neil Gaiman : quand les reines prennent leur destin en main

    Directory of Open Access Journals (Sweden)

    Stéphanie Schneider

    2016-12-01

    Full Text Available Dans le recueilintitulé "Rags and Bones: New Twists on Timeless Tales", chaque auteur choisissait un conte qui l’avait particulièrement touché (soit inspiré, émerveillé ou profondément agacé, le désossait et le reconstruisait à l’attention des jeunes lecteurs actuels. Ainsi, réécrit d’un point de vue contemporain, chacun des contes du recueil se propose, tout en rendant hommage aux textes sources, de soulever un débat particulier. Nous axerons le nôtre autour du destin des personnages féminins.

  3. Worldwide research productivity on tramadol: a bibliometric analysis.

    Science.gov (United States)

    Sweileh, Waleed M; Shraim, Naser Y; Zyoud, Sa'ed H; Al-Jabi, Samah W

    2016-01-01

    Pain management and safe use of analgesics is an important medical issue. Tramadol is an old analgesic with controversial properties. Evaluation of worldwide scientific output on tramadol has not been explored. Therefore, the main objective of this study was to give a bibliometric overview of global research productivity on tramadol. SciVerse Scopus was used to retrieve and quantitatively and qualitatively analyze worldwide publications on tramadol. A total of 2059 original and review research articles on tramadol were retrieved from Scopus. Forty-six documents (2.23 %) were published in Anesthesia and Analgesia Journal whereas 30 (1.46 %) were published in Arzneimittel Forschung Drug Research Journal. Retrieved tramadol documents were published from 71 countries and appeared in 160 peer reviewed journals. Although the United States of America (259; 12.86 %) had the largest contribution to tramadol publications; the contribution by other countries like Turkey (232; 11.27) India (189; 8.09 %) and Germany (176; 8.56 % was not far away from that of USA. The most productive institution was Grunenthal, Germany (47; 2.28 %) followed by Tehran University of Medical Sciences, Iran (29; 1.41 %), and, Ortho-McNeil Pharmaceutical Incorporated, USA (25; 1.21 %). Of the 2059 documents, there were 370 documents about dependence. The leading institution in documents pertaining to tramadol dependence was Grunenthal GmbH (18; 4.86 %) followed by Ortho-McNeil Pharmaceutical Incorporated (17; 4.59 %). The current study showed that there is an obvious interest in tramadol research. More efforts are needed to clarify the abuse potential and safety profile of tramadol to help in determining the legal status of tramadol. Collaboration among pharmaceutical industry, clinical researchers and academic institutions can improve research quantity and quality on tramadol.

  4. Noticing relevant problem features: activating prior knowledge affects problem solving by guiding encoding

    Science.gov (United States)

    Crooks, Noelle M.; Alibali, Martha W.

    2013-01-01

    This study investigated whether activating elements of prior knowledge can influence how problem solvers encode and solve simple mathematical equivalence problems (e.g., 3 + 4 + 5 = 3 + __). Past work has shown that such problems are difficult for elementary school students (McNeil and Alibali, 2000). One possible reason is that children's experiences in math classes may encourage them to think about equations in ways that are ultimately detrimental. Specifically, children learn a set of patterns that are potentially problematic (McNeil and Alibali, 2005a): the perceptual pattern that all equations follow an “operations = answer” format, the conceptual pattern that the equal sign means “calculate the total”, and the procedural pattern that the correct way to solve an equation is to perform all of the given operations on all of the given numbers. Upon viewing an equivalence problem, knowledge of these patterns may be reactivated, leading to incorrect problem solving. We hypothesized that these patterns may negatively affect problem solving by influencing what people encode about a problem. To test this hypothesis in children would require strengthening their misconceptions, and this could be detrimental to their mathematical development. Therefore, we tested this hypothesis in undergraduate participants. Participants completed either control tasks or tasks that activated their knowledge of the three patterns, and were then asked to reconstruct and solve a set of equivalence problems. Participants in the knowledge activation condition encoded the problems less well than control participants. They also made more errors in solving the problems, and their errors resembled the errors children make when solving equivalence problems. Moreover, encoding performance mediated the effect of knowledge activation on equivalence problem solving. Thus, one way in which experience may affect equivalence problem solving is by influencing what students encode about the

  5. Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu).

    Science.gov (United States)

    Luan, Jinwei; Li, Xianglan; Guo, Rutao; Liu, Shanshan; Luo, Hongyu; You, Qingshan

    2016-06-01

    Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA)-enhancing X-ray susceptibility in FaDu cells. The cDNA was isolated from FaDu cells treated with 0 X-ray, 8 Gy X-ray, or 8 Gy X-ray + RITA. Then, cDNA libraries were created and sequenced using next generation sequencing, and each assay was repeated twice. Subsequently, differentially expressed genes (DEGs) were identified using Cuffdiff in Cufflinks and their functions were predicted by pathway enrichment analyses. Genes that were constantly up- or down-regulated in 8 Gy X-ray-treated FaDu cells and 8 Gy X-ray + RITA-treated FaDu cells were obtained as RITA genes. Afterward, the protein-protein interaction (PPI) relationships were obtained from the STRING database and a PPI network was constructed using Cytoscape. Furthermore, ClueGO was used for pathway enrichment analysis of genes in the PPI network. Total 2,040 and 297 DEGs were identified in FaDu cells treated with 8 Gy X-ray or 8 Gy X-ray + RITA, respectively. PARP3 and NEIL1 were enriched in base excision repair, and CDK1 was enriched in p53 signaling pathway. RFC2 and EZH2 were identified as RITA genes. In the PPI network, many interaction relationships were identified (e.g., RFC2-CDK1, EZH2-CDK1 and PARP3-EZH2). ClueGO analysis showed that RFC2 and EZH2 were related to cell cycle. RFC2, EZH2, CDK1, PARP3 and NEIL1 may be associated, and together enhance the susceptibility of FaDu cells treated with RITA to the deleterious effects of X-ray.

  6. Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu)

    International Nuclear Information System (INIS)

    Luan, Jinwei; Li, Xianglan; Guo, Rutao; Liu, Shanshan; Luo, Hongyu; You, Qingshan

    2016-01-01

    Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA)-enhancing X-ray susceptibility in FaDu cells. The cDNA was isolated from FaDu cells treated with 0 X-ray, 8 Gy X-ray, or 8 Gy X-ray + RITA. Then, cDNA libraries were created and sequenced using next generation sequencing, and each assay was repeated twice. Subsequently, differentially expressed genes (DEGs) were identified using Cuffdiff in Cufflinks and their functions were predicted by pathway enrichment analyses. Genes that were constantly up- or down-regulated in 8 Gy X-ray-treated FaDu cells and 8 Gy X-ray + RITA-treated FaDu cells were obtained as RITA genes. Afterward, the protein-protein interaction (PPI) relationships were obtained from the STRING database and a PPI network was constructed using Cytoscape. Furthermore, ClueGO was used for pathway enrichment analysis of genes in the PPI network. Total 2,040 and 297 DEGs were identified in FaDu cells treated with 8 Gy X-ray or 8 Gy X-ray + RITA, respectively. PARP3 and NEIL1 were enriched in base excision repair, and CDK1 was enriched in p53 signaling pathway. RFC2 and EZH2 were identified as RITA genes. In the PPI network, many interaction relationships were identified (e.g., RFC2-CDK1, EZH2-CDK1 and PARP3-EZH2). ClueGO analysis showed that RFC2 and EZH2 were related to cell cycle. RFC2, EZH2, CDK1, PARP3 and NEIL1 may be associated, and together enhance the susceptibility of FaDu cells treated with RITA to the deleterious effects of X-ray

  7. Misconceptions in Astronomy: Before and After a Constructivist Learning Environment

    Science.gov (United States)

    Ruzhitskaya, Lanika; Speck, A.

    2009-01-01

    We present results of a pilot study on college students’ misconceptions in astronomy. The study was conducted on the campus of a Midwestern university among 43 non-science major students enrolled in an introductory astronomy laboratory course. The laboratory course was based on a constructivist learning environment where students learned astronomy by doing astronomy. During the course, students worked with educational simulations created by Project CLEA team and RedShift College Education Astronomy Workbook by Bill Walker as well as were involved in think-pair-share discussions based on Lecture-Tutorials (Prather et al 2008). Several laboratories were prompted by an instructor's brief presentations. On the first and last days of the course students were surveyed on what their beliefs were about causes of the seasons, the moon's apparent size in the sky and its phases, planetary orbits, structure of the solar system, the sun, distant stars, and the nature of light. The majority of the surveys’ questions were based on Neil Comins’ 50 most commonly cited misconceptions. The outcome of the study showed that while students constructed correct understanding of a number of phenomena, they also created a set of new misconceptions. For example, if on the first day of the course, nine out of 43 students knew what caused the seasons on Earth; on the last day of the course, 20 students gained the similar understanding. However, by the end of the course more students believed that smaller planets must rotate faster based on the conservation of angular momentum and Kepler's laws. Our findings suggest that misconceptions pointed out by Neil Comins over a decade ago are still relevant today; and that learning based exclusively on simulations and collaborative group discussions does not necessarily produce the best results, but may set a ground for creating new misconceptions.

  8. STS-90 Pilot Scott Altman is suited up for launch

    Science.gov (United States)

    1998-01-01

    STS-90 Pilot Scott Altman is assisted during suit-up activities by Lockheed Suit Technician Valerie McNeil from Johnson Space Center in KSC's Operations and Checkout Building. Altman and the rest of the STS-90 crew will shortly depart for Launch Pad 39B, where the Space Shuttle Columbia awaits a second liftoff attempt at 2:19 p.m. EDT. His first trip into space, Altman is participating in a life sciences research flight that will focus on the most complex and least understood part of the human body - - the nervous system. Neurolab will examine the effects of spaceflight on the brain, spinal cord, peripheral nerves and sensory organs in the human body.

  9. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2001-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Neil Calder, Mrs Sudeshna Datta Cockerill, Mrs Andrée Fontbonne, Mrs Moniek Laurent and Mr Ulrich Liptow with regard to membership in the Pension Fund under the period with a Paid Associate contract, appeals dealt with on a collective basis. As the appellants have not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 10 to 31 August 2001.

  10. Book Review. Cultural Heritage in a Changing World

    Directory of Open Access Journals (Sweden)

    Ashika Prajnya Paramita

    2017-02-01

    Full Text Available Edited by Karol Jan Borowiecki, Neil Forbes, and Antonella Fresa, this collection of essays was developed within the RICHES Project to address the issues surrounding cultural heritage in the era of digital technologies. The 21st century has witnessed rapid developments in digital technologies that have led to major changes in all aspects of society. This book aims to reflect the relationship between cultural heritage and these changes. Written by experts from various background, this book implements an interdisciplinary approach its observations, and provides a comprehensive view of the changes that occur in the society. In various perspectives, the collection show how cultural heritage, mainly in Europe, should be preserved through digital availability and accessibility.

  11. British energy policy and the market for coal - minutes of evidence - Tuesday 1 December 1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-01

    The Committee set up to examine UK energy policy and the market for coal (particularly British Coal's place in that market), examined evidence from: Mr David Porter, Mr Neil Bryson, Mr Fergus Wiggin and Mr John Macadam (Association of Independent Electricity Producers); Mr John Collins, Mr John Wybrew, Dr Chris Fay and Mr Ian Wybrew-Bond (Shell UK Ltd); Sir James McKinnon and Mr Greg McGregor (Office of Gas Supply (OFGAS)). Aspects covered include consequences of British Coal's pit closure programme, UK natural gas reserves, and the effects of increased demand for natural gas due to the 'dash for gas' (i.e. generating electricity from natural gas rather than coal).

  12. Divadlo on teater, Nitra on linn / Tiina Talts

    Index Scriptorium Estoniae

    Talts, Tiina

    2006-01-01

    Rahvusvahelisest teatrifestivalist "Divadelna Nitra" ("Teatraalne Nitra") Slovakkias 22. - 27. septembrini. Lühidalt lavastustest Georg Brüchner "Woyzeck" (Wojciech Boguslawski teater, Poola, lavastaja Maja Kleczewska); Thomas Bernhard "Before retirement" (Slovakkia teater Astorka-Korzo'90, lavastaja Juraj Nvota); Tatjana Tolstaja "Sonja" (Läti Riia Uus Teater, lavastaja Alvis Hermanis); Michel Houllebecq "Platform" (Belgia NTGent, lavastaja Johan Simons); William Shakespeare "Richard III" (Tšehhi Rahvusteater, lavastaja Michal Docekal); Neil LaBute "The shape of things" (Slovakkia Andrej Bagari Teater, lavastajad Roman Olekshak ja Maja Hrieshik); Rainald Goetz-Martin Heidegger "The consolation of the country path" (Tšehhi kodanike ühendus Mezery, lavastaja Miroslav Bambushek); Mark Ravenhill "Product" (Inglismaa Paines Plough, lavastaja Ravenhill); Anton Tshehhov "Ivanov" (Slovakkia Kammerteater, lavastaja Roman Polak)

  13. Modeling of Focused Acoustic Field of a Concave Multi-annular Phased Array Using Spheroidal Beam Equation

    International Nuclear Information System (INIS)

    Yu Lili; Shou Wende; Hui Chun

    2012-01-01

    A theoretical model of focused acoustic field for a multi-annular phased array on concave spherical surface is proposed. In this model, the source boundary conditions of the spheroidal beam equation (SBE) for multi-annular phased elements are studied. Acoustic field calculated by the dynamic focusing model of SBE is compared with numerical results of the O'Neil and Khokhlov-Zabolotskaya-Kuznetsov (KZK) model, respectively. Axial dynamic focusing and the harmonic effects are presented. The results demonstrate that the dynamic focusing model of SBE is good valid for a concave multi-annular phased array with a large aperture angle in the linear or nonlinear field. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  14. Autonomy, nudging and post-truth politics.

    Science.gov (United States)

    Keeling, Geoff

    2017-11-16

    In his excellent essay, 'Nudges in a post-truth world', Neil Levy argues that 'nudges to reason', or nudges which aim to make us more receptive to evidence, are morally permissible. A strong argument against the moral permissibility of nudging is that nudges fail to respect the autonomy of the individuals affected by them. Levy argues that nudges to reason do respect individual autonomy, such that the standard autonomy objection fails against nudges to reason. In this paper, I argue that Levy fails to show that nudges to reason respect individual autonomy. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  15. Hirm, raha ja armastus / Margot Visnap, Kadi Herkül, Immo Mihkelson

    Index Scriptorium Estoniae

    Visnap, Margot, 1959-

    1999-01-01

    Teleteatri aastaringist - ETV kaheksa lavastust seitsmelt lavastajalt : Toomas Hussar/Ervin Õunapuu "Linnapea ehk Hirmu põhivormid". Rezh. T. Hussar. Eetris 1. jaan. 1998; A.H. Tammsaare/Ain Prosa "Ma armastasin sakslast". Rezh. A. Prosa. Eetris 24. veebr. 1998; Dennis Potter "Sa oled koor minu kohvis". Rezh. Vilja Palm. Eetris 1. jaan. 1999; Ain Prosa/Karl Ristikivi "lihtne lugu, lõpuga". Rezh. Ain Prosa. Eetris 28. nov. 1998; Betti Alver/Margus Kasterpalu "Tuulearmuke". Rezh. Elo Selirand. Eetris 23. mail 1998; Faama Filmi ja ETV teleteatri koostöö "Isa", sts. ja rezh. Mart Kivastik. Eetris 28. märtsil 1998; "Lilled Leale", sts. ja rezh. Olle Mirme Toomas Vindi novelli põhjal; Rein Saluri "Andke neile andeks", lav. Talvo Pabut. Eetris 19. okt. 1998

  16. A simple solution to type specialization

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Partial evaluation specializes terms, but traditionally this specialization does not apply to the type of these terms. As a result, specializing, e.g., an interpreter written in a typed language, which requires a “universal” type to encode expressible values, yields residual programs with type tags...... all over. Neil Jones has stated that getting rid of these type tags was an open problem, despite possible solutions such as Torben Mogensen's “constructor specialization.” To solve this problem, John Hughes has proposed a new paradigm for partial evaluation, “Type Specialization”, based on type...... from the universal type to the specific type of the residual program. Standard partial evaluation then yields a residual program without type tags, simply and efficiently....

  17. Eessõna

    Directory of Open Access Journals (Sweden)

    Miia Rannikmäe

    2017-04-01

    Full Text Available Ligikaudu kümme aastat on nn Rocardi raporti "Science education now: A renewed pedagogy for the future of Europe" avaldamisest saadik olnud loodusteaduslik ja matemaatikaharidus Euroopa Liidus varasemast suurema tähelepanu all. Selle eesmärk on suurendada loodusteadustes, inseneri- ja matemaatikavaldkonnas karjääri valivate inimeste hulka, et tagada liikmesriikide areng neile erialadele tugineva innovatsiooni kaudu. Ka Euroopa Komisjoni hiljutises raportis "Science education for responsible citizenship" (2015 rõhutatakse, et tulevikusuundumused eeldavad kõigi ühiskonnaliikmete senisest paremat arusaamist loodusteadustest ja tehnoloogiast, et tagada nende aktiivne ja vastutustundlik osalemine otsustusprotsessis ja teadmistepõhises innovatsioonis. Muutus algab aga koolist, kus tuleb senisest enam pöörata tähelepanu loodusteadusliku-tehnoloogiaalase kirjaoskuse kõrgematele tasemetele.

  18. Performativitatea spaţiului public. Strategii legate de patrimoniul industrial

    Directory of Open Access Journals (Sweden)

    Letiţia Bărbuică

    2012-12-01

    Full Text Available The paper introduces the concept of performativity as originally described by Judith Butler end explained by Neil Leach. The concept will be extended to the public space as a key factor in perceiving the city as it is described by mental maps. Overlapping the map of Bucharest's industrial heritage onto the mental map describing the safety perception in the city it will become evident that rehabilitating the industrial heritage has implication beyond saving a unique piece of history. In doing so the mental map of the city can be changed in some simple steps and the whole city can take advantage of this. The project of rehabilitation of former ”Cartea Românească” printing House is small example in this respect.

  19. Report Assesses Nutrient Pollution in U.S. Streams and Aquifers

    Science.gov (United States)

    Showstack, Randy

    2010-10-01

    Concentrations of nutrients in many U.S. streams and aquifers have remained the same or have increased since the early 1990s, according to a new decadal assessment entitled “Nutrients in the nation's streams and groundwater, 1992-2004,” released by the U.S. Geological Survey (USGS) on 24 September. “Despite improvements in water quality made by reducing point sources of nutrients, our data show that nonpoint sources of nutrients have resulted in concentrations of both nitrogen and phosphorus far above criteria recommended by [the U.S. Environmental Protection Agency] for the protection of aquatic life,” Neil Dubrovsky, project chief for USGS's National Water-Quality Assessment (NAWQA) Program, said at a briefing when the report was released. While USGS continues to sample for nutrient concentrations, the report assessment period concluded in 2004.

  20. Oranzh häire : Kremli niiditõmbajad kardavad revolutsiooni tulekut / Neil Buckley, Stefan Wagstyl ; tõlk. Erik Aru

    Index Scriptorium Estoniae

    Buckley, Neil

    2005-01-01

    Autorite sõnul püüab Kreml tõkestada mehhanisme ja organisatsioone, mis võiksid toetada opositsiooni presidendikandidaadi esiletõusu. Kreml on andnud ka märku, et tihendatakse valvet kolmanda sektori asutuste üle. Endine asepeaminister Boriss Nemtsov peab oranzhi revolutsiooni toimumist Venemaal võimatuks, tulla võib punane või pruun revolutsioon. Lisa: Putin kinnitab, et kolmandat korda ei kandideeri

  1. Briti väliskomisjoni esimehe sõnul polnud neil Lissaboni leppe referendum vajalik / Mike Gapes ; intervjueerinud Evelyn Kaldoja

    Index Scriptorium Estoniae

    Gapes, Mike

    2009-01-01

    Briti alamkoja väliskomisjoni leiboristist juht Mike Gapes vastab küsimustele, mis puudutavad brittide võimalust hääletada Lissaboni leppe üle, Schengenist ja eurotsoonist välja jäämist ning lisasõdurite saatmist Afganistani

  2. Standard Model Physics at the LHC

    CERN Document Server

    CERN. Geneva

    1999-01-01

    1. Top Physics : Single top production and top polarization, D. O'Neil. Top mass determination, spin correlations and t-tbar asymmetries, L. Sonnenschein. FCNC-induced production and decays, S. Slabospitsky. MC tools for signals and backgrounds, M. Mangano. Plans for the writing of the final report, Conveners. Top physics: Discussion. 2. Electroweak physics (cont.) : Anomalous triple gauge boson couplings: analysis, strategies, and form factor considerations, M. Dobbs. Sensitivity to anomalous triple gauge boson couplings, W. Thuemmel. Drell-Yan production of W,Z with electroweak corrections, S. Dittmaier. Vector boson self-couplings and effective field theory, J.R. Pelaez. Recent theoretical progress, Z. Kunszt. Electroweak physics: Discussion. Recent theoretical progress in b production, G. Ridolf. Studies on b production, S. Gennai. Comparison of most recent b-production theoretical computations with PYTHIA, A. Kharchilava. Possibilities for b production measurements, P. Vikas. B production: Discussion....

  3. Socialization Moving Children and Teenagers in the Contemporary Polish Family [Przesunięcie socjalizacyjne dzieci i młodzieży we współczesnej rodzinie polskiej

    Directory of Open Access Journals (Sweden)

    Paulina FORMA

    2017-11-01

    Full Text Available Changes in the functioning of the family constitute the important social issue in our times, particularly because upturns of negative phenomena are distinct, such as divorces, long-term departures, the breaking of family bonds. Relating them additionally to civilization and cultural changes it is possible to conclude that they are contributing also to the socialisation shift as described by Neil Postman, or Zbigniew Kwieciński, Zbyszko Melosik, Bogusław Śliwerski. The dysfunctional familyand its wrong/incomplete structure is an indication of educational destructiveness. Therefore these circles are more and more often characteristic as failing and not satisfying essential needs of the socialised generations. The present text constitutes an attempt of a theoretical description of changes in the functioning of the family in the context of the socialization changes taking place.

  4. Action Française and culture : Life, Times and Legacy

    Directory of Open Access Journals (Sweden)

    Catherine Fraixe

    2011-12-01

    Full Text Available Review of: Olivier Dard, Michel Leymarie, Neil McWilliam (éds, Le maurrassisme et la culture. L’Action française. Culture, société, politique (III, Villeneuve-d’Ascq, Presses universitaires du Septentrion, 2010. This book is the result of a collective work on the intellectual hegemony which the Action Française exercised in France in the interwar period. It studies some of the main actors who constructed Maurrassism, the stategies which allowed them to dominate French cultural life from the beginning of the 1920s to the end of World War II and their ideology. It shows how this ideology was disseminated in different fields, history, literature, music, etc. and how this plural approach contributed to the success of a movement whose aim was to disqualify the very idea of democracy.

  5. A contribuição de Milton Santos para os estudos de ecossistemas das mídias

    Directory of Open Access Journals (Sweden)

    Fabio B. Josgrilberg

    2015-01-01

    Full Text Available El artículo tiene como objetivo presentar posibles aportes del geógrafo brasileño Milton Santos al análisis de los ecosistemas de los medios. El texto busca dialogar con la tradición de los estudios comunicacionales conocidos como ecología de los medios, que es altamente influenciada por nombres como Marshall McLuhan, Neil Postman y Walter Ong. El artículo también se apoya en conceptos y metáforas retiradas de las ciencias de los ecosistemas, y concluye que el principal aporte de Santos al debate está en cómo él articula la cuestión del poder económico y técnico a su análisis del espacio geográfico haciendo uso de abordajes sistémicos y dialécticos.

  6. A Simple Solution to Type Specialization

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Partial evaluation specializes terms, but traditionally this specialization does not apply to the type of these terms. As a result, specializing, e.g., an interpreter written in a typed language, which requires a “universal” type to encode expressible values, yields residual programs with type tags...... all over. Neil Jones has stated that getting rid of these type tags was an open problem, despite possible solutions such as Torben Mogensen's “constructor specialization.” To solve this problem, John Hughes has proposed a new paradigm for partial evaluation, “Type Specialization”, based on type...... inference instead of being based on symbolic interpretation. Type Specialization is very elegant in principle but it also appears non-trivial in practice. Stating the problem in terms of types instead of in terms of type encodings suggests a very simple type-directed solution, namely, to use a projection...

  7. Origins fourteen billion years of cosmic evolution

    CERN Document Server

    Tyson, Neil deGrasse

    2004-01-01

    Origins explores cosmic science's stunning new insights into the formation and evolution of our universe--of the cosmos, of galaxies and galaxy clusters, of stars within galaxies, of planets that orbit those stars, and of different forms of life that take us back to the first three seconds and forward through three billion years of life on Earth to today's search for life on other planets. Drawing on the current cross-pollination of geology, biology and astrophysics, Origins explains the thrilling daily breakthroughs in our knowledge of the universe from dark energy to life on Mars to the mysteries of space and time. Distilling complex science in clear and lively prose, co-authors Neil deGrasse Tyson and Donald Goldsmith conduct a galvanising tour of the cosmos revealing what the universe has been up to while turning part of itself into us.

  8. Instability Rules: The Ten Most Amazing Ideas of Modern Science

    Science.gov (United States)

    Flowers, Charles

    2002-03-01

    World-altering discoveries that reveal a universe of uncertainty and constant change Whether probing the farthest reaches of the vast universe or exploring the microscopic world of genetics and the subatomic world of quantum mechanics, Instability Rules is a remarkably informative and engaging look at ten milestone discoveries and their discoverers-a wide range of very human personalities whose insights have dramatically altered our most basic assumptions about human existence during the last century. The stories include Edwin Hubble and the expanding universe, Alfred Wegener and continental drift, Neils Bohr and quantum mechanics, Alan Turing and artificial intelligence, and James Watson and Francis Crick and DNA. Also covering discoveries of the twenty-first century that are already refining these and other ideas, Instability Rules is an exhilarating, sometimes amusing encounter with the defining scientific discoveries of our age.

  9. President's message: Dues increase will help build the foundation for AGU's future success

    Science.gov (United States)

    McPhaden, Michael J.

    2012-09-01

    The world is a very different place than it was 43 years ago. In 1969, Jimi Hendrix rocked the legendary Woodstock music festival, Neil Armstrong took the first steps on the Moon, and U.S. drivers paid an average of 35 cents a gallon for gas. Today, digital music files have replaced vinyl records, NASA's Curiosity rover is transmitting data and imagery from the surface of Mars, and a growing number of cars run on alternative fuels. In the same way, 43 years ago AGU was a very different organization. Membership hovered around 10,000, and the Fall Meeting was still in its infancy. Today, AGU's membership has increased to more than 61,000, Fall Meeting attendance has topped 20,000, and an entire generation of geoscientists who weren't even born in 1969 now comprises 28% of our current membership.

  10. ITER ITA Newsletter. No. 28, February 2006

    International Nuclear Information System (INIS)

    2006-03-01

    This issue of ITER ITA (ITER transitional Arrangements) newsletter contains concise information about ITER related activities and meetings, namely, the first staff arrival at the Cadarache Joint Work Site (JWS) and IAEA activities in 2005 in support of fusion and ITER. On 30 January 2006 the first staff began working at JWS. Among the first arrivals are members of the Safety, Environment and Health Group, who are charged to prepare the necessary license applications in close cooperation with the host. Other arrivals include members of the Nuclear Technology Division and Site Buildings and Assembly Group charged with the preparations for initial construction work. A branch of the Configuration Management Group, Design Integration Division, has also been installed at Cadarache. The acting Head of the JWS is Eisuke Tada who was previously acting Head at Naka, where Neil Mitchell has taken over the position

  11. Reflections on the discovery of fission

    International Nuclear Information System (INIS)

    Peieris, Rudolf

    1989-01-01

    In this article an eminent scientist looks back on the fifty years since the discovery of nuclear fission. Starting with Enrico Fermi's work with neutrons in the 1930s, the author then introduces Neils Bohr's ideas about atomic structure. The puzzle of what happens when uranium was bombarded by neutrons was gradually unravelled. Finally by 1939 it was becoming realised that the uranium nucleus had split in two. Gradually physicists began to speculate on the possibility of harnessing some of the energy stored in the nucleus and on the idea of a chain reaction. As the end of the decade approached, workers in the field combined with military forces to develop a weapon based on this reaction, the Manhatton Project. The author notes how fast an obscure, esoteric piece of physics research, can be taken up into the military and political area. (UK)

  12. Understandings and Tendencies of Edutainment in Turkey: An Evaluation Based on Neil Postman's Criticism on Education, Entertainment and Technology

    Science.gov (United States)

    Yaylaci, Filiz Goktuna; Yaylaci, Ali Faruk

    2016-01-01

    There have been a wide range of studies on the interplay between education and technology. Furthermore, there are many other studies aimed at analyzing the scholarly output on this subject with a holistic approach. However the studies are mostly focused on the facilitator role of technology. Although the idea that educational processes have become…

  13. REVEALING TYPE Ia SUPERNOVA PHYSICS WITH COSMIC RATES AND NUCLEAR GAMMA RAYS

    International Nuclear Information System (INIS)

    Horiuchi, Shunsaku; Beacom, John F.

    2010-01-01

    Type Ia supernovae (SNe Ia) remain mysterious despite their central importance in cosmology and their rapidly increasing discovery rate. The progenitors of SNe Ia can be probed by the delay time between progenitor birth and explosion as SNe Ia. The explosions and progenitors of SNe Ia can be probed by MeV nuclear gamma rays emitted in the decays of radioactive nickel and cobalt into iron. We compare the cosmic star formation and SN Ia rates, finding that their different redshift evolution requires a large fraction of SNe Ia to have large delay times. A delay-time distribution of the form t -α with α = 1.0 ± 0.3 provides a good fit, implying that 50% of SNe Ia explode more than ∼1 Gyr after progenitor birth. The extrapolation of the cosmic SN Ia rate to z = 0 agrees with the rate we deduce from catalogs of local SNe Ia. We investigate prospects for gamma-ray telescopes to exploit the facts that escaping gamma rays directly reveal the power source of SNe Ia and uniquely provide tomography of the expanding ejecta. We find large improvements relative to earlier studies by Gehrels et al. in 1987 and Timmes and Woosley in 1997 due to larger and more certain SN Ia rates and advances in gamma-ray detectors. The proposed Advanced Compton Telescope, with a narrow-line sensitivity ∼60 times better than that of current satellites, would, on an annual basis, detect up to ∼100 SNe Ia (3σ) and provide revolutionary model discrimination for SNe Ia within 20 Mpc, with gamma-ray light curves measured with ∼10σ significance daily for ∼100 days. Even more modest improvements in detector sensitivity would open a new and invaluable astronomy with frequent SN Ia gamma-ray detections.

  14. Estilos de aprendizaje y metacognición en estudiantes de psicología de Arequipa (Learning and Metacognition Styles in Psychology Students from Arequipa

    Directory of Open Access Journals (Sweden)

    Walter Lizandro Arias Gallegos

    2014-12-01

    Full Text Available Resumen En este estudio se presenta la correlación de los estilos de aprendizaje según el modelo de Kolb (divergente, asimilador, convergente y acomodador con la metacognición y sus tres dimensiones (autoconocimiento, autorregulación y evaluación. Para ello, se utilizó el Inventario de Estilos de Aprendizaje de Kolb (α = 0.8 y el Inventario de Estrategias Metacognitivas de O’Neil y Abedi (α = 0.90. La muestra estuvo conformada por 273 estudiantes de psicología de tres universidades de Arequipa, seleccionados mediante la técnica de grupos intactos. Los resultados indican que el estilo divergente es el predominante en las tres universidades y que existen altos porcentajes de estudiantes con niveles bajos de metacognición, autoconocimiento, autorregulación y evaluación. Para el caso de la Universidad Nacional de San Agustín (UNSA y la Universidad Católica de Santa María (UCSM, se hallaron relaciones entre el estilo de aprendizaje convergente y la metacognición. Hubo relaciones inversas entre este estilo y el estilo divergente. El análisis de varianza indica que los estilos de aprendizaje no tienen efecto sobre la metacognición ni sus dimensiones. Abstract In this study, learning styles were correlated according to Kolb’s model (divergent, assimilator, convergent and usher with metacognition and its three dimensions (self-knowledge, self-regulation and evaluation. For this purpose, Kolb’s Styles of Learning Inventory was used (α = 0.87 and O’Neil and Abedi’s Metacognitive Strategies Inventory (α = 0.90. The sample was made-up of 273 psychology students from three universities in Arequipa that were selected through the intact group technique. The results indicated that the divergent style is prevalent in the three universities, and there are high percentages of students with low levels of metacognition, self-knowledge, self-regulation and evaluation. In the case of the Universidad Nacional de San Agustin (UNSA and the

  15. SPIN-selling

    CERN Document Server

    Rackham, Neil

    1995-01-01

    True or false? In selling high-value products or services: "closing" increases your chance of success; it is essential to describe the benefits of your product or service to the customer; objection handling is an important skill; and open questions are more effective than closed questions. All false, says Neil Rackham. He and his team studied more than 35,000 sales calls made by 10,000 sales people in 23 countries over 12 years. Their findings revealed that many of the methods developed for selling low-value goods just don't work for major sales. Rackham went on to introduce his SPIN-selling method, where SPIN describes the whole selling process - Situation questions, Problem questions, Implication questions, Need-payoff questions. SPIN-selling provides you with a set of simple and practical techniques which have been tried in many of today's leading companies with dramatic improvements to their sales performance.

  16. Comment 3 on workshop in political institutions - problems of institutional analysis

    International Nuclear Information System (INIS)

    Hurwicz, L.

    1992-01-01

    The following is mostly an elaboration of the comments the author made during the discussion stimulated by the McGinnis-Ostrom paper (McG-O hereinafter). It will be seen that I have added references to other papers by these two authors, kindly made available to me after the conference. He had been ignorant of this literature, and we are am grateful both to the authors and to the organizers of the conference for so broadening my horizons. MacNeil et al. (1991, p. 220, as cited on p. 1 of McG-O) states that the design of appropriate institutions is on the Rio open-quotes Earth Summitclose quotes agenda: open-quotes the heads of state ... will be asked to ... (4) initiate major reforms of open-quote international institutions to enable nations to manage global interdependence and to implement Agenda 21 as well as the conventions

  17. Evaluating urban form and location effects on cycling based on Danish micro-data

    DEFF Research Database (Denmark)

    Nielsen, Thomas Alexander Sick; Olafsson, Anton Stahl; Carstensen, Trine Agervig

    , infrastructure and the willingness to cycle (McNeil, 2011). Cycling as travel mode or activity may be placed somewhere in between ‘street life’ which is highly sensitive to environmental qualities, and a more utility oriented mode of travel moving between origins and destinations. Following Forsyth and Krizek...... transportation to some degree is a competing alternative. Retail jobs per resident within a very convenient 500 meter walking range indicating main street and central area locations, as well as network connectivity within the 500 meter range also contribute to lower probabilities of cycling – indicating......: number of retail jobs pr. resident within walking range which turned insignificant when the respondents access to a bicycle is included in the set of control variables This indicate that people living in very central locations more often do not possess a bicycle which again may be a combined effect...

  18. Mask industry quality assessment

    Science.gov (United States)

    Strott, Al; Bassist, Larry

    1994-12-01

    Product quality and timely delivery are two of the most important parameters in determining the success of a mask manufacturing facility. Because of the sensitivity of this data, very little was known about industry performance in these areas until an assessment was authored and presented at the 1993 BACUS Symposium by Larry Regis of Intel Corporation, Neil Paulsen of Intel Corporation, and James A. Reynolds of Reynolds Consulting. This data has been updated and will be published and presented at this year's BACUS Symposium. Contributor identities will again remain protected by utilizing Arthur Andersen & Company to compile the submittals. Participation was consistent with last year's representation of over 75% of the total merchant and captive mask volume in the United States. The data compiled includes shipments, customer return rate, customer return reasons from 1988 through Q2, 1994, performance to schedule, plate survival yield, and throughput time (TPT).

  19. The constitutional consequences of European Union integration : [bakalaureusetöö] / Maris Ilves ; Tartu Ülikool, õigusteaduskond ; juhendaja: Neil J. Brennan

    Index Scriptorium Estoniae

    Ilves, Maris

    1998-01-01

    Euroopa Majandusühenduse arengutee Euroopa Liiduni, Euroopa Liidu õiguse printsiibid (ülimuslikkus, otsese mõju põhimõte, kaudse mõju põhimõte, riiklik vastutus), Euroopa Liidu föderaalsed omadused, Euroopa põhiseaduse võimalikkusest

  20. Is European integration causing Europe to become more nationalist? Evidence from the 2007 - 9 financial crisis / Alina Polyakova, Neil Fligstein

    Index Scriptorium Estoniae

    Polyakova, Alina

    2016-01-01

    Artiklis käsitletakse eurointegratsiooni ühtse identiteedi kujunemise aspektis. Väidetakse, et EL-i integratsioon on tegelikult viinud selleni, et Euroopa kodanikud väärtustavad euroidentideedist enam rahvuslikku identiteeti ja soovivad, et nende riikide valitsused kaitseksid neid