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Sample records for fibrous cap thickness

  1. Fibrous Cap Thickness by Optical Coherence Tomography In Vivo.

    Science.gov (United States)

    Kini, Annapoorna S; Vengrenyuk, Yuliya; Yoshimura, Takahiro; Matsumura, Mitsuaki; Pena, Jacobo; Baber, Usman; Moreno, Pedro; Mehran, Roxana; Maehara, Akiko; Sharma, Samin; Narula, Jagat

    2017-02-14

    Optical coherence tomography (OCT) imaging is considered to be the only imaging modality with sufficient resolution to measure fibrous cap thickness (FCT) in vivo. However, reproducibility of the measurements in vivo has been unsatisfactory. The authors aimed to investigate whether satisfactory reproducibility of FCT measurements by OCT in vivo can be achieved between independent observers. One hundred seventy OCT pullbacks were analyzed by 2 independent observers with intravascular imaging expertise in accordance with current guidelines to assess the interobserver variability of FCT measurement by intraclass correlation coefficient (ICC). The main sources of the variability were analyzed and incorporated in lesion assessment criteria. The same 170 OCT pullbacks were reanalyzed by the same observers using the developed criteria, and the interobserver reproducibility of the measurements was reassessed. On the basis of the developed criteria, a third independent observer interpreted all 170 OCT images. Assessment of the maximal lipid arc was also undertaken similarly before and after the development of interpretation criteria. The original ICC of the FC thickness was 0.56 (95% confidence interval [CI]: 0.38 to 0.69). The poor definition of necrotic core facing border of FC and the neointimal presence of macrophages and calcification contributed to the high interobserver variability of FCT measurement. The ICC of FCT measurements by OCT in vivo was 0.88 (95% CI: 0.80 to 0.93) after we developed lesion assessment criteria. The ICC for the maximal lipid arc assessment before and after was 0.76 and 0.82 respectively. The third independent observer was extensively coached and returned the ICC of 0.82 (95% CI: 0.74 to 0.87) with observer 1 and 0.90 (95% CI: 0.86 to 0.94) with observer 2. Careful consideration of OCT features mimicking fibroatheroma lesions and imaging artifacts contributed to significantly higher levels of interobserver agreement. Interobserver

  2. [Correlation between serum inflammatory cytokine levels and fibrous cap thickness of fibrofatty plaque in coronary culprit lesions].

    Science.gov (United States)

    Zhong, Y; Ye, F; You, W; Wu, Z M

    2017-07-24

    Objective: To identify the correlation between serum inflammatory cytokine levels including high sensitive C reactive protein (hs-CRP) and lipoprotein associated phospholipase (Lp-PLA2) and the fibrous cap thickness of fibrofatty plaque in coronary culprit lesions. Methods: Clinical data of 117 patients with selective coronary artery angiography diagnosed coronary artery disease admitted to our hospital from January 2015 to January 2016 were retrospective analyzed. According to type of coronary disease, patients were divided into 3 subgroups: SAP group (containing 47 stable angina patients), UAP group (containing 52 unstable angina patients), and NSTEMI group(containing 18 acute non ST segment elevation myocardial infarction patients). Serum hs-CRP and Lp-PLA2 levels were measured before subsequent procedures. The characteristics of the culprit lesions were detected by optical coherence tomogarpgy(OCT) before interventional treatment, and the correlation between hs-CRP and Lp-PLA2 and the fibrous cap thickness of fibrofatty plaque in coronary culprit lesions were analyzed. Results: (1) The serum levels of hs-CRP (2.13(1.04, 4.75)μg/L vs. 1.02(0.60, 1.29)μg/L and 1.30(1.03, 1.96)μg/L, all Pcap thickness of fibrofatty plaque in coronary culprit lesions were smaller in NSTEMI group and UAP group than in SAP group(50(50, 60)μm and 60(50, 90)μm vs. 130(80, 190)μm, all P0.05). Proportion of thin-cap fibroatheroma plaque(82.35%(14/18) vs. 19.15%(9/47) and 63.46%(33/52), all P0.05). (3) Pearson correlation analysis showed that serum levels of hs-CRP(r=-0.233, Pcap thickness of fibrofatty plaques. Spearman correlation analysis showed that serum levels of hs-CRP were positively correlated with plaque rupture(r=0.409, Pcap fibroatheroma plaque(OR=1.017, Pcap fibroatheroma plaque, plaque rupture and thrombosis was significantly higher in the NSTEMI patients, while the prevalence of calcification in plaque is more often in SAP patients. Increased serum levels of Lp-PLA2

  3. Lumen irregularity dominates the relationship between mechanical stress condition, fibrous-cap thickness, and lumen curvature in carotid atherosclerotic plaque.

    Science.gov (United States)

    Teng, Zhongzhao; Sadat, Umar; Ji, Guangyu; Zhu, Chengcheng; Young, Victoria E; Graves, Martin J; Gillard, Jonathan H

    2011-03-01

    High mechanical stress condition over the fibrous cap (FC) has been widely accepted as a contributor to plaque rupture. The relationships between the stress, lumen curvature, and FC thickness have not been explored in detail. In this study, we investigate lumen irregularity-dependent relationships between mechanical stress conditions, local FC thickness (LT(FC)), and lumen curvature (LC(lumen)). Magnetic resonance imaging slices of carotid plaque from 100 patients with delineated atherosclerotic components were used. Two-dimensional structure-only finite element simulations were performed for the mechanical analysis, and maximum principal stress (stress-P₁) at all integral nodes along the lumen was obtained. LT(FC) and LC(lumen) were computed using the segmented contour. The lumen irregularity (L-δir) was defined as the difference between the largest and the smallest lumen curvature. The results indicated that the relationship between stress-P₁, LT(FC), and LC(lumen) is largely dependent on L-δir. When L-δir ≥ .31 (irregular lumen), stress-P₁ strongly correlated with lumen curvature and had a weak/no correlation with local FC thickness, and in 73.4% of magnetic resonance (MR) slices, the critical stress (maximum of stress-P₁ over the diseased region) was found at the site where the lumen curvature was large. When L-δir ≤ 0.28 (relatively round lumen), stress-P₁ showed a strong correlation with local FC thickness but weak/no correlation with lumen curvature, and in 71.7% of MR slices, the critical stress was located at the site of minimum FC thickness. Using lumen irregularity as a method of identifying vulnerable plaque sites by referring to the lumen shape is a novel and simple method, which can be used for mechanics-based plaque vulnerability assessment.

  4. Effect of Early Pitavastatin Therapy on Coronary Fibrous-Cap Thickness Assessed by Optical Coherence Tomography in Patients With Acute Coronary Syndrome: The ESCORT Study.

    Science.gov (United States)

    Nishiguchi, Tsuyoshi; Kubo, Takashi; Tanimoto, Takashi; Ino, Yasushi; Matsuo, Yoshiki; Yamano, Takashi; Terada, Kosei; Emori, Hiroki; Katayama, Yosuke; Taruya, Akira; Ozaki, Yuichi; Shiono, Yasutsugu; Shimamura, Kunihiro; Kameyama, Takeyoshi; Kitabata, Hironori; Yamaguchi, Tomoyuki; Tanaka, Atsushi; Hozumi, Takeshi; Akasaka, Takashi

    2017-09-09

    The aim of the present study was to assess the effect of early statin therapy on fibrous-cap thickness in coronary plaques of patients with acute coronary syndrome (ACS) by using optical coherence tomography. Statins can contribute to the stabilization of coronary plaques. This is a prospective, randomized, active-controlled, single-center study. Patients with ACS and untreated dyslipidemia were enrolled and randomly allocated (ratio 1:1) to either the early statin group (received pitavastatin 4 mg/day from baseline) or the late statin group (received pitavastatin 4 mg/day from 3 weeks after the baseline). Optical coherence tomography was performed at baseline, 3-week, and 36-week follow-up to assess nonculprit coronary plaques in 53 patients. Between baseline and 3-week follow-up, fibrous-cap thickness increased in the early statin group (140 μm [interquartile range (IQR):120 to 170 μm] to 160 μm [IQR: 130 to 190 μm]; p = 0.017), but decreased in the late statin group (135 μm [IQR: 110 to 183 μm] to 130 μm [IQR: 108 to 160 μm]; p = 0.020). The percentage of increase in fibrous-cap thickness between baseline and 3-week follow-up was significantly greater in the early statin group compared with the late statin group (8.3% [IQR: 0.0% to 21.4%] vs. -5.8% [IQR: -16.0% to 0.0%]; p cap thickness increased comparably in the 2 groups. Early therapy with pitavastatin 4 mg/day for patients with ACS provided an increase in fibrous-cap thickness in coronary plaques during the first 3 weeks of follow-up and a further increase during 36 weeks of follow-up. The study was registered with UMIN Clinical Trial Registry (Effect of PitavaStatin on Coronary Fibrous-cap Thickness - Assessment by Fourier-Domain Optical CoheRence Tomography (ESCORT): UMIN000002678). Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  5. Arterial luminal curvature and fibrous-cap thickness affect critical stress conditions within atherosclerotic plaque: an in vivo MRI-based 2D finite-element study.

    Science.gov (United States)

    Teng, Zhongzhao; Sadat, Umar; Li, Zhiyong; Huang, Xueying; Zhu, Chengcheng; Young, Victoria E; Graves, Martin J; Gillard, Jonathan H

    2010-10-01

    High mechanical stress in atherosclerotic plaques at vulnerable sites, called critical stress, contributes to plaque rupture. The site of minimum fibrous cap (FC) thickness (FC(MIN)) and plaque shoulder are well-documented vulnerable sites. The inherent weakness of the FC material at the thinnest point increases the stress, making it vulnerable, and it is the big curvature of the lumen contour over FC which may result in increased plaque stress. We aimed to assess critical stresses at FC(MIN) and the maximum lumen curvature over FC (LC(MAX)) and quantify the difference to see which vulnerable site had the highest critical stress and was, therefore, at highest risk of rupture. One hundred patients underwent high resolution carotid magnetic resonance (MR) imaging. We used 352 MR slices with delineated atherosclerotic components for the simulation study. Stresses at all the integral nodes along the lumen surface were calculated using the finite-element method. FC(MIN) and LC(MAX) were identified, and critical stresses at these sites were assessed and compared. Critical stress at FC(MIN) was significantly lower than that at LC(MAX) (median: 121.55 kPa; inter quartile range (IQR) = [60.70-180.32] kPa vs. 150.80 kPa; IQR = [91.39-235.75] kPa, p LC(MAX) only was used, then 112 out of 352 would be underestimated. Stress analysis at FC(MIN) and LC(MAX) should be used for a refined mechanical risk assessment of atherosclerotic plaques, since material failure at either site may result in rupture.

  6. Atherosclerotic plaque fibrous cap assessment under an oblique scan plane orientation in carotid MRI

    NARCIS (Netherlands)

    Nieuwstadt, H.A.; Van der Lugt, A.; Kassar, Z.A.M.; Breeuwer, M.; Van der Steen, A.F.W.; Gijsen, F.J.H.

    2014-01-01

    Carotid magnetic resonance imaging (MRI) is used to noninvasively assess atherosclerotic plaque fibrous cap (FC) status, which is closely related to ischemic stroke. Acquiring anisotropic voxels improves in-plane visualization, however, an oblique scan plane orientation could then obscure a FC (i.e.

  7. Characterization of fracture behavior of human atherosclerotic fibrous caps using a miniature single edge notched tensile test.

    Science.gov (United States)

    Davis, Lindsey A; Stewart, Samantha E; Carsten, Christopher G; Snyder, Bruce A; Sutton, Michael A; Lessner, Susan M

    2016-10-01

    One well-established cause of ischemic stroke is atherosclerotic plaque rupture in the carotid artery. Rupture occurs when a tear in the fibrous cap exposes highly thrombogenic material in the lipid core. Though some fibrous cap material properties have been measured, such as ultimate tensile strength and stress-strain responses, there has been very little, if any, data published regarding the fracture behavior of atherosclerotic fibrous caps. This study aims to characterize the qualitative and quantitative fracture behavior of human atherosclerotic plaque tissue obtained from carotid endarterectomy samples using two different metrics. Uniaxial tensile experiments along with miniature single edge notched tensile (MSENT) experiments were performed on strips of isolated fibrous cap. Crack tip opening displacement (CTOD) and stress in the un-cracked segment (UCS) were measured at failure in fibrous cap MSENT specimens subjected to uniaxial tensile loading. Both CTOD and the degree of crack blunting, measured as the radius of curvature of the crack tip, increased as tearing propagated through the tissue. Higher initial stress in the UCS is significantly correlated with higher collagen content and lower macrophage content in the fibrous cap (ρ=0.77, P=0.009; ρ=-0.64, P=0.047; respectively). Trends in the data show that higher CTOD is inversely related to collagen content, though the sample size in this study is insufficient to statistically substantiate this relationship. To the authors' knowledge, this is the pioneering study examining the fracture behavior of fibrous caps and the first use of the CTOD metric in vascular tissue. A tear in the fibrous cap of atherosclerotic plaque can lead to ischemic stroke or myocardial infarction. While there is some information in the literature regarding quantitative measures of fibrous cap failure, there is little information regarding the behavior of the tissue during failure. This study examines the failure behavior of fibrous

  8. Model-based cap thickness and peak cap stress prediction for carotid MRI.

    Science.gov (United States)

    Kok, Annette M; van der Lugt, Aad; Verhagen, Hence J M; van der Steen, Antonius F W; Wentzel, Jolanda J; Gijsen, Frank J H

    2017-07-26

    A rupture-prone carotid plaque can potentially be identified by calculating the peak cap stress (PCS). For these calculations, plaque geometry from MRI is often used. Unfortunately, MRI is hampered by a low resolution, leading to an overestimation of cap thickness and an underestimation of PCS. We developed a model to reconstruct the cap based on plaque geometry to better predict cap thickness and PCS. We used histological stained plaques from 34 patients. These plaques were segmented and served as the ground truth. Sections of these plaques contained 93 necrotic cores with a cap thickness Caps below the MRI resolution (n=31) were (digitally removed and) reconstructed according to the geometry-based model. Cap thickness and PCS were determined for the ground truth, readers, and reconstructed geometries. Cap thickness was 0.07mm for the ground truth, 0.23mm for the readers, and 0.12mm for the reconstructed geometries. The model predicts cap thickness significantly better than the readers. PCS was 464kPa for the ground truth, 262kPa for the readers and 384kPa for the reconstructed geometries. The model did not predict the PCS significantly better than the readers. The geometry-based model provided a significant improvement for cap thickness estimation and can potentially help in rupture-risk prediction, solely based on cap thickness. Estimation of PCS estimation did not improve, probably due to the complex shape of the plaques. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  9. Axisymmetric buckling of laminated, moderately thick shallow conical cap

    Energy Technology Data Exchange (ETDEWEB)

    Dumir, P.C.; Dube, G.P.; Joshi, S. [Applied Mechanics Dept., I.I.T. Delhi, New Delhi (India)

    2001-05-01

    Axisymmetric buckling and postbuckling analysis is presented for a moderately thick, laminated shallow conical cap under static transverse load. Marguerre-type, first-order shear deformation shallow-shell theory is formulated in terms of transverse deflection w, the rotation {psi} of the normal to the midsurface and the stress function {phi}. The governing equations are solved by the orthogonal point-collocation method. Clamped conical caps and simple supports with movable and immovable edge conditions are considered. Typical numerical results are presented, illustrating the effect of various parameters. The dependence of the effect of the shear deformation on the thickness parameter, boundary conditions, ratio of Young's moduli and cap height is investigated. (orig.)

  10. Axisymmetric buckling of laminated thick annular spherical cap

    Science.gov (United States)

    Dumir, P. C.; Dube, G. P.; Mallick, A.

    2005-03-01

    Axisymmetric buckling analysis is presented for moderately thick laminated shallow annular spherical cap under transverse load. Buckling under central ring load and uniformly distributed transverse load, applied statically or as a step function load is considered. The central circular opening is either free or plugged by a rigid central mass or reinforced by a rigid ring. Annular spherical caps have been analysed for clamped and simple supports with movable and immovable inplane edge conditions. The governing equations of the Marguerre-type, first order shear deformation shallow shell theory (FSDT), formulated in terms of transverse deflection w, the rotation ψ of the normal to the midsurface and the stress function Φ, are solved by the orthogonal point collocation method. Typical numerical results for static and dynamic buckling loads for FSDT are compared with the classical lamination theory and the dependence of the effect of the shear deformation on the thickness parameter for various boundary conditions is investigated.

  11. Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap.

    Directory of Open Access Journals (Sweden)

    Sylvia T Nurnberg

    2015-05-01

    Full Text Available Recent genome wide association studies have identified a number of genes that contribute to the risk for coronary heart disease. One such gene, TCF21, encodes a basic-helix-loop-helix transcription factor believed to serve a critical role in the development of epicardial progenitor cells that give rise to coronary artery smooth muscle cells (SMC and cardiac fibroblasts. Using reporter gene and immunolocalization studies with mouse and human tissues we have found that vascular TCF21 expression in the adult is restricted primarily to adventitial cells associated with coronary arteries and also medial SMC in the proximal aorta of mouse. Genome wide RNA-Seq studies in human coronary artery SMC (HCASMC with siRNA knockdown found a number of putative TCF21 downstream pathways identified by enrichment of terms related to CAD, including "vascular disease," "disorder of artery," and "occlusion of artery," as well as disease-related cellular functions including "cellular movement" and "cellular growth and proliferation." In vitro studies in HCASMC demonstrated that TCF21 expression promotes proliferation and migration and inhibits SMC lineage marker expression. Detailed in situ expression studies with reporter gene and lineage tracing revealed that vascular wall cells expressing Tcf21 before disease initiation migrate into vascular lesions of ApoE-/- and Ldlr-/- mice. While Tcf21 lineage traced cells are distributed throughout the early lesions, in mature lesions they contribute to the formation of a subcapsular layer of cells, and others become associated with the fibrous cap. The lineage traced fibrous cap cells activate expression of SMC markers and growth factor receptor genes. Taken together, these data suggest that TCF21 may have a role regulating the differentiation state of SMC precursor cells that migrate into vascular lesions and contribute to the fibrous cap and more broadly, in view of the association of this gene with human CAD, provide

  12. Heat Transfer Modeling and Validation for Optically Thick Alumina Fibrous Insulation

    Science.gov (United States)

    Daryabeigi, Kamran

    2009-01-01

    Combined radiation/conduction heat transfer through unbonded alumina fibrous insulation was modeled using the diffusion approximation for modeling the radiation component of heat transfer in the optically thick insulation. The validity of the heat transfer model was investigated by comparison to previously reported experimental effective thermal conductivity data over the insulation density range of 24 to 96 kg/cu m, with a pressure range of 0.001 to 750 torr (0.1 to 101.3 x 10(exp 3) Pa), and test sample hot side temperature range of 530 to 1360 K. The model was further validated by comparison to thermal conductivity measurements using the transient step heating technique on an insulation sample at a density of 144 kg/cu m over a pressure range of 0.001 to 760 torr, and temperature range of 290 to 1090 K.

  13. How Thick is the North Polar Ice Cap on Mars?

    Science.gov (United States)

    2008-01-01

    This map shows the thickness of the north polar layered deposits on Mars as measured by the Shallow Radar instrument on NASA's Mars Reconnaissance Orbiter. The Shallow Radar instrument was provided by the Italian Space Agency. Its operations are led by the University of Rome and its data are analyzed by a joint U.S.-Italian science team. JPL, a division of the California Institute of Technology, Pasadena, manages the Mars Reconnaissance Orbiter for the NASA Science Mission Directorate, Washington

  14. How Thick is the North Polar Ice Cap on Mars?

    Science.gov (United States)

    2008-01-01

    This map shows the thickness of the north polar layered deposits on Mars as measured by the Shallow Radar instrument on NASA's Mars Reconnaissance Orbiter. The Shallow Radar instrument was provided by the Italian Space Agency. Its operations are led by the University of Rome and its data are analyzed by a joint U.S.-Italian science team. JPL, a division of the California Institute of Technology, Pasadena, manages the Mars Reconnaissance Orbiter for the NASA Science Mission Directorate, Washington

  15. Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    DEFF Research Database (Denmark)

    Andersen, Stine Hasselholt; Lykkesfeldt, Jens; Larsen, Jytte Overgaard

    2015-01-01

    Abstract In neuroscience, the optical fractionator technique is frequently used for unbiased cell number estimations. Although unbiased in theory, the practical application of the technique is often biased by the necessity of introducing a guard zone at one side of the disector to counter lost caps...... methacrylate) sections were inspected for lost caps to evaluate the possibility of whole section thickness counting with the optical fractionator technique and hippocampal granular cell nucleoli density differences along the z-axis were assessed with a z-axis analysis. No lost caps were found in the examined...

  16. Experimental Study on the Effect of Steel-fibre in Concrete Thick Cap

    Institute of Scientific and Technical Information of China (English)

    LU Hailin; ZHANG Mingyuan; LI Zhongxian

    2007-01-01

    The effect of steel fibre used in concrete was systematically analyzed by model testing of 30 2-pile thick caps of steel-fibre reinforced concrete, in which the model scale was 1:5. The experiment system composed of a loading device, strain measurement system and a data-acquisition system was used, also an electromechanic centigrade scale, a lens and a YJ-25 static resistance strainometer were used.The experimental results show that the volumetric rate of steel fibre and draw ratio have an important influence on its load-bearing capacity. The incorporation of steel fibre can effectively improve the extension and reduce the thickness of the caps.

  17. Effects of Snowfall on the Thickness and Stability of Mars' Seasonal Ice Caps

    Science.gov (United States)

    Hayne, P. O.; Paige, D. A.; Aharonson, O.; Schofield, J. T.; Kass, D. M.; Kleinboehl, A.; Heavens, N. G.; Shirley, J. H.; McCleese, D. J.

    2012-12-01

    Seasonal exchange of carbon dioxide between the Martian atmosphere and ice caps is responsible for cyclical variations of ~30% in global atmospheric pressure, as well as for the growth and retreat of the seasonal ice caps. Energy balance and general circulation models have had limited success in reproducing the important aspects of this cycle, largely due to uncertainties in the radiative properties (albedo and emissivity) of the ice caps. Evidence from remote sensing by several different orbital investigations suggests that snowfall consisting primarily of solid CO2 contributes substantial material to the growing seasonal caps, strongly affecting their radiative properties. However, the mass of material deposited as snow, its spatial and temporal variation, and its effect on the energy budget, have all remained uncertain. Using data from the Mars Climate Sounder (MCS), we have quantified and mapped snow cloud formation and surface accumulation based on opacity profiles and calculated infrared cooling rates. We then compared the derived snowfall distribution to seasonal cap thicknesses derived from Mars Orbiter Laser Altimeter (MOLA) "crossover" data. Large variations in the occurrence, thickness, and timing of snow clouds are observed, with the most extensive and persistent clouds observed over the south polar residual cap (SPRC). We find a strong correlation between clouds, "cold spots" (regions of suppressed thermal emission), and seasonal cap thickness. Furthermore, some of these regions of high snow cloud activity also exhibit high solar albedo in the spring and summer. Together, these results suggest that granular deposits of CO2 snow: 1) are thicker (probably due to lower density) on average than "slab ice" formed by direct vapor deposition; 2) reduce energy loss by thermal emission during the polar night; and 3) reduce energy gain by reflecting solar radiation during spring and summer. As the snowiest place on Mars, the SPRC exhibits all of these properties

  18. 桩帽设计中的厚板分析%THICK PLATE ANALYSIS WITH APPLICATION TO PILE CAP DESIGN

    Institute of Scientific and Technical Information of China (English)

    郑榕明; 张勇慧

    2004-01-01

    The thick plate is commonly used for the pile cap and the transfer plate, and a proper analysis of it can greatly affect the cost of the thick plate. In actual practice, soft support condition is sometimes adopted by engineers for modeling of thick plates. In this paper, the limitations of soft support in the determination of deflection and bending moment with very thick plates are studied. The distribution of superstructure loadings to pile caps and piles is also carefully investigated.

  19. Micromagnetic simulation of thickness variation of Neel cap in hybrid Bloch-Neel domain wall

    Energy Technology Data Exchange (ETDEWEB)

    Lu Mai [Key Lab. of Opto-Electronic Technology and Intelligent Control, Lanzhou Jiaotong University, Ministry of Education, P.O. Box 73, 118 West Anning Road, Lanzhou 730070, Gansu (China) and Department of Signals and Systems, Chalmers University of Technology, SE-412 96, Gothenburg (Sweden)]. E-mail: m.lu@mail.edu.cn; Leonard, Paul J. [Department of Electronic and Electrical Engineering, University of Bath, Claverton Down, Bath BA2 7AY (United Kingdom)

    2005-08-01

    The hybrid Bloch-Neel domain wall in iron film has been investigated using three-dimensional micromagnetic calculations. Magnetization distributions in the film plane and cross-section are presented. In the film plane the rotation of magnetization in the 180 deg domain wall takes two different patterns from the bottom layer to the top layer. In cross-section the C-shaped magnetization distribution with hybrid Bloch-Neel domain wall has been found. The thickness of the top Neel cap changes from its largest value as the C-shaped magnetization distribution appears, and becomes thinner as the C-shaped magnetization distribution gradually moves and grows up. The thickness variation of the bottom Neel cap changes in a similar way, but with a reversal pattern. The results in this paper will enrich our knowledge of magnetic domain and domain wall patterns in magnetic materials.

  20. Comparison of Two Cap Thickness in Small Incision Lenticule Extraction: 100μm versus 160μm.

    Science.gov (United States)

    He, Miao; Wang, Wei; Ding, Hui; Zhong, Xingwu

    To compare the changes of biomechanical properties, endothelial cell density (ECD), and posterior corneal elevation (PCE) after femtosecond small incision lenticule extractions (SMILEs) with 100μm versus 160μm cap thicknesses. A total of 12 rabbits were randomly assigned into two groups of 6 each. SMILE was performed at a depth of either 160μm (160-cap group) or 100μm (100-cap group). Corneal biomechanics, PCE, ECD were evaluated pre-operatively, 1week, 1 month, 2 months, 3 months, and 4 months post-operatively by Pentacam, Corvis ST, in vivo confocal microscopy (IVCM) respectively. The Young's modulus was obtained by strip-extensometry test 4 months after surgery. At each time point, the second applanation time (A2T) was similar between the groups with the exception of 4 months after surgery (22.66±0.16 ms in the 160-cap group versus 21.75±0.29 ms in the 100-cap group, p = 0.004). Neither deformation amplitude (DA) nor the first applanationtime (A1T) were significantly different between the two groups. The postoperative posterior surface did not shift forward, the changes of PCE and ECD were not significantly different between the two groups at any observation time. Young's modulus was higher in the 160-cap group than that in the 100-cap group with no statistical significance (P>0.05). Regression analyses showed that the PCE changes and Young's modulus were not affected by cap thickness (CT) or residual stromal bed thickness (RBT) (All P>0.05). The differences of corneal biomechanics, posterior surface elevation, or ECD changes were quite small when using 100μm or 160μm cap thicknesses in SMILE.

  1. Ability of combined Near-Infrared Spectroscopy-Intravascular Ultrasound (NIRS-IVUS) imaging to detect lipid core plaques and estimate cap thickness in human autopsy coronary arteries

    Science.gov (United States)

    Grainger, S. J.; Su, J. L.; Greiner, C. A.; Saybolt, M. D.; Wilensky, R. L.; Raichlen, J. S.; Madden, S. P.; Muller, J. E.

    2016-03-01

    The ability to determine plaque cap thickness during catheterization is thought to be of clinical importance for plaque vulnerability assessment. While methods to compositionally assess cap integrity are in development, a method utilizing currently available tools to measure cap thickness is highly desirable. NIRS-IVUS is a commercially available dual imaging method in current clinical use that may provide cap thickness information to the skilled reader; however, this is as yet unproven. Ten autopsy hearts (n=15 arterial segments) were scanned with the multimodality NIRS-IVUS catheter (TVC Imaging System, Infraredx, Inc.) to identify lipid core plaques (LCPs). Skilled readers made predictions of cap thickness over regions of chemogram LCP, using NIRS-IVUS. Artery segments were perfusion fixed and cut into 2 mm serial blocks. Thin sections stained with Movat's pentachrome were analyzed for cap thickness at LCP regions. Block level predictions were compared to histology, as classified by a blinded pathologist. Within 15 arterial segments, 117 chemogram blocks were found by NIRS to contain LCP. Utilizing NIRSIVUS, chemogram blocks were divided into 4 categories: thin capped fibroatheromas (TCFA), thick capped fibroatheromas (ThCFA), pathological intimal thickening (PIT)/lipid pool (no defined cap), and calcified/unable to determine cap thickness. Sensitivities/specificities for thin cap fibroatheromas, thick cap fibroatheromas, and PIT/lipid pools were 0.54/0.99, 0.68/0.88, and 0.80/0.97, respectively. The overall accuracy rate was 70.1% (including 22 blocks unable to predict, p = 0.075). In the absence of calcium, NIRS-IVUS imaging provided predictions of cap thickness over LCP with moderate accuracy. The ability of this multimodality imaging method to identify vulnerable coronary plaques requires further assessment in both larger autopsy studies, and clinical studies in patients undergoing NIRS-IVUS imaging.

  2. Fibrous dysplasia

    Science.gov (United States)

    ... chap 22. Czerniak B. Fibrous dysplasia and related lesions. In: Czerniak B, ed. Bone Tumors. 2nd ... Assistant Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also ...

  3. Bicomponent Fibrous Scaffolds Made through Dual-source Dual-power Electrospinning: Dual Delivery of rhBMP-2 and Ca-P Nanoparticles and Enhanced Biological Performances.

    Science.gov (United States)

    Wang, Chong; Weijia Lu, William; Wang, Min

    2017-04-05

    Electrospun scaffolds incorporated with both calcium phosphates (Ca-P) and bone morphogenetic protein-2 (BMP-2) have been used for bone tissue regeneration. However, in most cases BMP-2 and Ca-P were simply mixed and loaded in a monolithic structure, risking low BMP-2 loading level, reduced BMP-2 biological activity, uncontrolled BMP-2 release and inhomogeneous Ca-P distribution. In this investigation, novel bicomponent scaffolds having evenly distributed rhBMP-2-containing fibers and Ca-P nanoparticle-containing fibers were made using an established dual-source dual-power electrospinning technique with the assistance of emulsion electrospinning and blend electrospinning. The release behaviour of rhBMP-2 and Ca(2+) ions could be separately tuned and the released rhBMP-2 retained a 68% level for biological activity. MC3T3-E1 cells showed high viability and normal morphology on scaffolds. Compared to monocomponent scaffolds, enhanced cell proliferation, alkaline phosphatase activity, cell mineralization and gene expression of osteogenic markers were achieved for bicomponent scaffolds due to the synergistic effect of rhBMP-2 and Ca-P nanoparticles. Bicomponent scaffolds with a double mass elicited further enhanced cell adhesion, spreading, proliferation and osteogenic differentiation. This article is protected by copyright. All rights reserved.

  4. The exciton-longitudinal-optical-phonon coupling in InGaN/GaN single quantum wells with various cap layer thicknesses

    Institute of Scientific and Technical Information of China (English)

    Hu Xiao-Long; Zhang Jiang-Yong; Shang Jing-Zhi; Liu Wen-Jie; Zhang Bao-Ping

    2010-01-01

    This paper studies the exciton-longitudinal-optical-phonon coupling in InGaN/GaN single quantum wells with various cap layer thicknesses by low temperature photoluminescence (PL) measurements. With increasing cap layer thickness, the PL peak energy shifts to lower energy and the coupling strength between the exciton and longitudinal-optical (LO) phonon, described by Huang-Rhys factor, increases remarkably due to an enhancement of the internal electric field. With increasing excitation intensity, the zero-phonon peak shows a blueshift and the Huang-Rhys factor decreases. These results reveal that there is a large built-in electric field in the well layer and the exciton-LO-phonon coupling is strongly affected by the thickness of the cap layer.

  5. Effect of Mo capping layers thickness on the perpendicular magnetic anisotropy in MgO/CoFeB based top magnetic tunnel junction structure

    Science.gov (United States)

    Liu, Yi; Zhu, Kai-Gui; Zhong, Hui-Cai; Zhu, Zheng-Yong; Yu, Tao; Ma, Su-De

    2016-11-01

    A detailed study of the magnetic characterizations of the top structure MgO/CoFeB/Mo is presented. The samples show strong perpendicular magnetic anisotropy (PMA) when the thickness of CoFeB is 0.9 nm and 1.1 nm. The saturation magnetic moment and interface anisotropy constant are 1566 emu/cm3 and 3.75 erg/cm2, respectively. The magnetic dead layer (MDL) is about 0.23 nm in this system. Furthermore, strong capping layer thickness dependence is also observed. The strong PMA of 1.1 nm CoFeB only exists in a Mo cap layer thickness window of 1.2-2 nm. To maintain PMA, the metal layer could not be too thin or thick in these multilayers. The oxidation and diffusion of the metal capping layer should be respectively responsibility for the degradation of PMA in these thin or thick metal capping layer samples. Project supported by the National Fundamental Research Program of China (Grant No. 2011CB921804) and Beijing Key Subject Foundation of Condensed Matter Physics, China (Grant No. 0114023).

  6. Harnessing Photovoltage: Effects of Film Thickness, TiO2 Nanoparticle Size, MgO and Surface Capping with DSCs.

    Science.gov (United States)

    Cheema, Hammad; Delcamp, Jared H

    2017-01-25

    High photovoltage dye-sensitized solar cells (DSCs) offer an exceptional opportunity to power electrocatalysts for the production of hydrogen from water and the reduction of CO2 to usable fuels with a relatively cost-effective, low-toxicity solar cell. Competitive recombination pathways such as electron transfer from TiO2 films to the redox shuttle or oxidized dye must be minimized to achieve the maximum possible photovoltage (Voc) from DSC devices. A high Voc of 882 mV was achieved with the iodide/triiodide redox shuttle and a ruthenium NCS-ligated dye, HD-2-mono, by utilizing a combined approach of (1) modulating the TiO2 surface area through film thickness and nanoparticle size selection, (2) addition of a MgO insulating layer, and (3) capping available TiO2 film surface sites post film sensitization with an F-SAM (fluorinated self-assembled monolayer) treatment. The exceptional Voc of 882 mV observed is the highest achieved for the popular NCS containing ruthenium sensitizers with >5% PCE and compares favorably to the 769 mV value observed under common device preparation conditions.

  7. Cradle Cap: Symptoms and Causes

    Science.gov (United States)

    Cradle cap Symptoms and causes By Mayo Clinic Staff Common signs of cradle cap include: Patchy scaling or thick crusts on the ... on the ears, eyelids, nose and groin. Cradle cap is common in newborns. It usually isn't ...

  8. Effect of GaN cap thickness on carrier dynamics in InGaN quantum wells

    DEFF Research Database (Denmark)

    Kopylov, Oleksii; Shirazi, Roza; Svensk, O.

    2012-01-01

    thickness of 3nm for achieving highest brightness emitters. At low temperature, we observe a behaviour that suggests that some surface states act as trapping centres for carriers rather than as a non-radiative recombination channel. Temperature dependence of the photoluminescence decay curves shows...

  9. Development of the Convective Boundary Layer Capping with a Thick Neutral Layer in Badanjilin: Observations and Simulations

    Institute of Scientific and Technical Information of China (English)

    HAN Bo; L(U) Shihua; AO Yinhuan

    2012-01-01

    In this study,the development of a convective boundary layer (CBL) in the Badanjilin region was investigated by comparing the observation data of two cases.A deep neutral layer capped a CBL that occurred on 30 August 2009.This case was divided into five sublayers from the surface to higher atmospheric elevations:surface layer,mixed layer,inversion layer,neutral layer,and sub-inversion layer.The development process of the CBL was divided into three stages:S1,S2,and S3.This case was quite different from the development of the three-layer CBL observed on 31 August 2009 because the mixed layer of the five-layer CBL (CBL5) eroded the neutral layer during S2.The specific initial structure of the CBL5 was correlated to the synoptic background of atmosphere during nighttime.The three-stage development process of the CBL5 was confirmed by six simulations using National Center for Atmospheric Research (USA) large-eddy simulation (NCAR-LES),and some of its characteristics are presented in detail.

  10. Cap effect of (Bi,Pb){sub 2}Sr{sub 2}Ca{sub 2}Cu{sub 3}O{sub y} thick films during post-annealing process

    Energy Technology Data Exchange (ETDEWEB)

    Tokuda, T. [Department of Electrical and Electronic Engineering, Tottori University, 4-101, Koyama-Minami, Tottori 680-8552 (Japan); Honda, S., E-mail: b03t3052@faradayele.tottori-u.ac.j [Department of Electrical and Electronic Engineering, Tottori University, 4-101, Koyama-Minami, Tottori 680-8552 (Japan); Kinoshita, K.; Kishida, S. [Department of Electrical and Electronic Engineering, Tottori University, 4-101, Koyama-Minami, Tottori 680-8552 (Japan)

    2009-10-15

    We prepared (Bi,Pb){sub 2}Sr{sub 2}Ca{sub 2}Cu{sub 3}O{sub y} (BiPb-2223) thick films on MgO substrates by a spin coating method and investigated their superconducting property. The surface of BiPb-2223 thick films was capped with MgO, Ag or BiPb-2223/MgO during sintering process. From the results of X-ray diffraction patterns and resistance-temperature characteristics, we found that the caps of MgO and Ag were useful for obtaining the 30 mum-BiPb-2223 thick films with the T{sub c} above 100 K. Although the T{sub c} of the thick films with the thickness less than 5 mum decreased, the T{sub c} of the BiPb-2223 films with the thickness less than 5 mum was improved by use of the BiPb-2223/MgO cap.

  11. Cervical Cap

    Science.gov (United States)

    ... I Help Someone Who's Being Bullied? Volunteering Cervical Cap KidsHealth > For Teens > Cervical Cap Print A A ... and a female's egg. How Does a Cervical Cap Work? The cervical cap keeps sperm from entering ...

  12. Craniofacial fibrous dysplasia

    Directory of Open Access Journals (Sweden)

    Aakarsh Jhamb

    2012-01-01

    Full Text Available Fibrous dysplasia can present clinically in varied forms which may appear as collision of different pathologic processes. We report a rare case of craniofacial fibrous dysplasia with coexisting epithelial lined cyst and superimposed osteomyelitis with sequestrum formation. Its clinical features and management with possible hypotheses are described along with the post operative course. Pertinent literature has been reviewed with emphasis on pathogenesis of this unique occurrence.

  13. Strength of Fibrous Composites

    CERN Document Server

    Huang, Zheng-Ming

    2012-01-01

    "Strength of Fibrous Composites" addresses evaluation of the strength of a fibrous composite by using its constituent material properties and its fiber architecture parameters. Having gone through the book, a reader is able to predict the progressive failure behavior and ultimate strength of a fibrous laminate subjected to an arbitrary load condition in terms of the constituent fiber and matrix properties, as well as fiber geometric parameters. The book is useful to researchers and engineers working on design and analysis for composite materials. Dr. Zheng-Ming Huang is a professor at the School of Aerospace Engineering & Applied Mechanics, Tongji University, China. Mr. Ye-Xin Zhou is a PhD candidate at the Department of Mechanical Engineering, the University of Hong Kong, China.

  14. Morphological and Stress Vulnerability Indices for Human Coronary Plaques and Their Correlations with Cap Thickness and Lipid Percent: An IVUS-Based Fluid-Structure Interaction Multi-patient Study.

    Directory of Open Access Journals (Sweden)

    Liang Wang

    2015-12-01

    Full Text Available Plaque vulnerability, defined as the likelihood that a plaque would rupture, is difficult to quantify due to lack of in vivo plaque rupture data. Morphological and stress-based plaque vulnerability indices were introduced as alternatives to obtain quantitative vulnerability assessment. Correlations between these indices and key plaque features were investigated. In vivo intravascular ultrasound (IVUS data were acquired from 14 patients and IVUS-based 3D fluid-structure interaction (FSI coronary plaque models with cyclic bending were constructed to obtain plaque wall stress/strain and flow shear stress for analysis. For the 617 slices from the 14 patients, lipid percentage, min cap thickness, critical plaque wall stress (CPWS, strain (CPWSn and flow shear stress (CFSS were recorded, and cap index, lipid index and morphological index were assigned to each slice using methods consistent with American Heart Association (AHA plaque classification schemes. A stress index was introduced based on CPWS. Linear Mixed-Effects (LME models were used to analyze the correlations between the mechanical and morphological indices and key morphological factors associated with plaque rupture. Our results indicated that for all 617 slices, CPWS correlated with min cap thickness, cap index, morphological index with r = -0.6414, 0.7852, and 0.7411 respectively (p<0.0001. The correlation between CPWS and lipid percentage, lipid index were weaker (r = 0.2445, r = 0.2338, p<0.0001. Stress index correlated with cap index, lipid index, morphological index positively with r = 0.8185, 0.3067, and 0.7715, respectively, all with p<0.0001. For all 617 slices, the stress index has 66.77% agreement with morphological index. Morphological and stress indices may serve as quantitative plaque vulnerability assessment supported by their strong correlations with morphological features associated with plaque rupture. Differences between the two indices may lead to better plaque

  15. Benign Fibrous Histiocytoma

    Directory of Open Access Journals (Sweden)

    Pushpa Varma

    2014-01-01

    Full Text Available Fibrous histiocytomas (FHs are mesenchymal tumors that may be benign or malignant. Ocular involvement by FHs is infrequent and primarily limited to the orbit. Rarely, FHs can also involve the conjunctiva and perilimbal area. We report the case of a 38-year-old male with lid, conjunctival, and neck FHs. The diagnosis was confirmed by histopathology.

  16. Calvarial malignant fibrous histiocytoma

    Directory of Open Access Journals (Sweden)

    Chhabra R

    2004-07-01

    Full Text Available Primary malignant fibrous histiocytoma (MFH of the central nervous system (CNS is uncommon. We report cases of two young patients of MFH arising from the cranial meninges and involving the adjacent skull and scalp. There was infiltration of the brain in one case. Both the lesions were excised and primary scalp repair was performed.

  17. Gastric Calcifying Fibrous Tumour

    Directory of Open Access Journals (Sweden)

    Tan Attila

    2006-01-01

    Full Text Available Intramucosal gastric tumours are most commonly found to be gastrointestinal stromal tumours or leiomyomas (smooth muscle tumours; however, a variety of other uncommon mesenchymal tumours can occur in the stomach wall. A rare benign calcifying fibrous tumour is reported and the endoscopic appearance, ultrasound findings and morphology are documented. A review of the literature found only two similar cases.

  18. Permeability and compression of fibrous porous media generated from dilute suspensions of fiberglass debris during a loss of coolant accident

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Saya, E-mail: sayalee@tamu.edu; Abdulsattar, Suhaeb S.; Vaghetto, Rodolfo; Hassan, Yassin A.

    2015-09-15

    Highlights: • Experimental investigation on fibrous debris buildup was conducted. • Head loss through fibrous media was recorded at different approach velocities. • A head loss model through fibrous media was proposed for high porosity (>0.99). • A compression model of fibrous media was developed. - Abstract: Permeability of fibrous porous media has been studied for decades in various engineering applications, including liquid purifications, air filters, and textiles. In nuclear engineering, fiberglass has been found to be a hazard during a Loss-of-Coolant Accident. The high energy steam jet from a break impinges on surrounding fiberglass insulation materials, producing a large amount of fibrous debris. The fibrous debris is then transported through the reactor containment and reaches the sump strainers. Accumulation of such debris on the surface of the strainers produces a fibrous bed, which is a fibrous porous medium that can undermine reactor core cooling. The present study investigated the buildup of fibrous porous media on two types of perforated plate and the pressure drop through the fibrous porous media without chemical effect. The development of the fibrous bed was visually recorded in order to correlate the pressure drop, the approach velocity, and the thickness of the fibrous porous media. The experimental results were compared to semi-theoretical models and theoretical models proposed by other researchers. Additionally, a compression model was developed to predict the thickness and the local porosity of a fibrous bed as a function of pressure.

  19. The nature of fibrous dysplasia

    Directory of Open Access Journals (Sweden)

    Lemmer Johan

    2009-11-01

    Full Text Available Abstract Fibrous dysplasia has been regarded as a developmental skeletal disorder characterized by replacement of normal bone with benign cellular fibrous connective tissue. It has now become evident that fibrous dysplasia is a genetic disease caused by somatic activating mutation of the Gsα subunit of G protein-coupled receptor resulting in upregulation of cAMP. This leads to defects in differentiation of osteoblasts with subsequent production of abnormal bone in an abundant fibrous stroma. In addition there is an increased production of IL-6 by mutated stromal fibrous dysplastic cells that induce osteoclastic bone resorption.

  20. [Craniofacial fibrous dysplasia].

    Science.gov (United States)

    Couturier, A; Aumaître, O; Mom, T; Gilain, L; André, M

    2016-12-01

    Fibrous dysplasia of bone is a benign, uncommon, sporadic, congenital skeletal disorder resulting in deformity. This disease arises from activating somatic mutation in GNAS which encodes the α subunit of the G stimulatory protein associated with proliferation of undifferentiated osteogenic cells resulting in marrow fibrosis, abnormal matrix production, and stimulation of osteoclastic resorption upon overproduction of IL-6 observed in dysplastic cells. Fibrous dysplasia may be monostotic or polyostotic. This mutation affecting many tissues, café au lait skin macules and endocrinopathies (precocious puberty, hyperthyroidism, growth hormone excess, Cushing syndrome) may be associated in McCune-Albright syndrome, but also myxoma in Mazabraud syndrome or phosphate diabetes. Diagnosis of craniofacial fibrous dysplasia should be considered in the presence of headache, neuralgia, sensory disorders (vision, hearing, balance, smelling), functional disorders (nasal obstruction, nasolacrimal duct obstruction, non-matching occlusion), infectious complications (sinusitis, otitis, mastoiditis). Such symptoms should lead to perform craniofacial CT scan completed with MRI. Bone biopsy is not systematic. Surgical treatment is discussed in cases of nervous complication, facial deformity or active lesions. In case of pain resistant to conventional analgesics, intravenous bisphosphonates can be proposed. In non-responder patients, several case reports suggest the efficacy of a monoclonal antibody directed against the IL-6 receptor which requires to be confirmed by randomized studies.

  1. Solitary fibrous tumor

    Directory of Open Access Journals (Sweden)

    Manlio Mencoboni

    2010-12-01

    Full Text Available Solitary fibrous tumor (SFT is a rare mesenchymal neoplasm which may be found everywhere in the body. It is now distinguished into two forms, pleural and extrapleural, which morphologically resemble each other. Abdomi­nal localizations are quite rare, with 10 cases only reported in bladder; rarely they can be source of paraneoplastic syndromes (i.e., hypoglycemia secondary to insulin-like growth factor. In April 2006 a 74-year-old white male presented with chills, diaphoresis and acute abdominal pain with hematuria. At admission in emergency he underwent an abdominal X-ray (no pathological findings and an ultrasound examination of the kidneys and urinary tract, which revealed a pelvic hyperechogenic neoformation measuring approximately 10¥8¥7 cm, compressing the bladder. Blood chemistry at admission revealed only a mild neutrophilic leucocytosis (WBC 16600, N 80%, L 11%, elevated fibrinogen and ESR, and hypoglycemia (38 mg/dL. Macro­scopic hematuria was evident, while urinocolture was negative. Contrast enhanced CT scan of the abdomen and pelvic region revealed a large round neoformation dislocating the bladder, with an evident contrast-enhanced periphery and a central necrotic area. Continuous infusion of glucose 5% solution was necessary in order to maintain blood glucose levels above 50 mg/dL. The patient underwent complete surgical resection of an ovoidal mass coated by adipose tissue, with well delimited margins; histological findings were consistent with solitary fibrous tumor (SFT. Hypoglycemia resolved completely with removal of the growth. In this case report we describe a SFT growing in the bladder, a quite rare localization, which presented a unique hypoglycemia. In contrast to the majority of cases reported in the literature, the behavior of this SFT was not aggressive, and, since the patient is still alive, surgical resection was considered conclusive.

  2. Dynamic atomic layer epitaxy of InN on/in +c-GaN matrix: Effect of “In+N” coverage and capping timing by GaN layer on effective InN thickness

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, Akihiko, E-mail: yoshi@faculty.chiba-u.jp [Center for SMART Green Innovation Research, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522 (Japan); Graduate School of Engineering, Kogakuin University, Hachioji, Tokyo 192-0015 (Japan); Kusakabe, Kazuhide; Hashimoto, Naoki [Center for SMART Green Innovation Research, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522 (Japan); Hwang, Eun-Sook; Itoi, Takaomi [Graduate School of Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522 (Japan)

    2016-01-11

    The growth front in the self-organizing and self-limiting epitaxy of ∼1 monolayer (ML)-thick InN wells on/in +c-GaN matrix by molecular beam epitaxy (MBE) has been studied in detail, with special attention given to the behavior and role of the N atoms. The growth temperatures of interest are above 600 °C, far higher than the typical upper critical temperature of 500 °C in MBE. It was confirmed that 2 ML-thick InN wells can be frozen/inserted in GaN matrix at 620 °C, but it was found that N atoms at the growth front tend to selectively re-evaporate more quickly than In atoms at temperatures higher than 650 °C. As a result, the effective thickness of inserted InN wells in the GaN matrix at 660–670 °C were basically 1 ML or sub-ML, even though they were capped by a GaN barrier at the time of 2 ML “In+N” coverage. Furthermore, it was found that the N atoms located below In atoms in the dynamic atomic layer epitaxy growth front had remarkably weaker bonding to the +c-GaN surface.

  3. Cap inflammation leads to higher plaque cap strain and lower cap stress: An MRI-PET/CT-based FSI modeling approach.

    Science.gov (United States)

    Tang, Dalin; Yang, Chun; Huang, Sarayu; Mani, Venkatesh; Zheng, Jie; Woodard, Pamela K; Robson, Philip; Teng, Zhongzhao; Dweck, Marc; Fayad, Zahi A

    2017-01-04

    Plaque rupture may be triggered by extreme stress/strain conditions. Inflammation is also implicated and can be imaged using novel imaging techniques. The impact of cap inflammation on plaque stress/strain and flow shear stress were investigated. A patient-specific MRI-PET/CT-based modeling approach was used to develop 3D fluid-structure interaction models and investigate the impact of inflammation on plaque stress/strain conditions for better plaque assessment. 18FDG-PET/CT and MRI data were acquired from 4 male patients (average age: 66) to assess plaque characteristics and inflammation. Material stiffness for the fibrous cap was adjusted lower to reflect cap weakening causing by inflammation. Setting stiffness ratio (SR) to be 1.0 (fibrous tissue) for baseline, results for SR=0.5, 0.25, and 0.1 were obtained. Thin cap and hypertension were also considered. Combining results from the 4 patients, mean cap stress from 729 cap nodes was lowered by 25.2% as SR went from 1.0 to 0.1. Mean cap strain value for SR=0.1 was 0.313, 114% higher than that from SR=1.0 model. The thin cap SR=0.1 model had 40% mean cap stress decrease and 81% cap strain increase compared with SR=1.0 model. The hypertension SR=0.1 model had 19.5% cap stress decrease and 98.6% cap strain increase compared with SR=1.0 model. Differences of flow shear stress with 4 different SR values were limited (Cap inflammation may lead to large cap strain conditions when combined with thin cap and hypertension. Inflammation also led to lower cap stress. This shows the influence of inflammation on stress/strain calculations which are closely related to plaque assessment. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Geometrical modeling of fibrous materials under compression

    Science.gov (United States)

    Maze, Benoit; Tafreshi, Hooman Vahedi; Pourdeyhimi, Behnam

    2007-10-01

    Many fibrous materials such as nonwovens are consolidated via compaction rolls in a so-called calendering process. Hot rolls compress the fiber assembly and cause fiber-to-fiber bonding resulting in a strong yet porous structure. In this paper, we describe an algorithm for generating three dimensional virtual fiberwebs and simulating the geometrical changes that happen to the structure during the calendering process. Fibers are assumed to be continuous filaments with square cross sections lying randomly in the x or y direction. The fibers are assumed to be flexible to allow bending over one another during the compression process. Lateral displacement is not allowed during the compaction process. The algorithm also does not allow the fibers to interpenetrate or elongate and so the mass of the fibers is conserved. Bending of the fibers is modeled either by considering a constant "slope of bending" or constant "span of bending." The influence of the bending parameters on the propagation of compression through the material's thickness is discussed. In agreement with our experimental observations, it was found that the average solid volume fraction profile across the thickness becomes U shaped after the calendering. The application of these virtual structures in studying transport phenomena in fibrous materials is also demonstrated.

  5. Cradle Cap (For Parents)

    Science.gov (United States)

    ... Kids to Be Smart About Social Media Cradle Cap (Infantile Seborrheic Dermatitis) KidsHealth > For Parents > Cradle Cap ( ... many babies develop called cradle cap. About Cradle Cap Cradle cap is the common term for seborrheic ...

  6. Death cap

    DEFF Research Database (Denmark)

    Rudbæk, Torsten R; Kofoed, Pernille Bouteloup; Bove, Jeppe

    2014-01-01

    Death cap (Amanita phalloides) is commonly found and is one of the five most toxic fungi in Denmark. Toxicity is due to amatoxin, and poisoning is a serious medical condition, causing organ failure with potential fatal outcome. Acknowledgement and clarification of exposure, symptomatic and focused...

  7. Apical cap

    Energy Technology Data Exchange (ETDEWEB)

    McLoud, T.C.; Isler, R.J.; Novelline, R.A.; Putman, C.E.; Simeone, J.; Stark, P.

    1981-08-01

    Apical caps, either unilateral or bilateral, are a common feature of advancing age and are usually the result of subpleural scarring unassociated with other diseases. Pancoast (superior sulcus) tumors are a well recognized cause of unilateral asymmetric apical density. Other lesions arising in the lung, pleura, or extrapleural space may produce unilateral or bilateral apical caps. These include: (1) inflammatory: tuberculosis and extrapleural abscesses extending from the neck; (2) post radiation fibrosis after mantle therapy for Hodgkin disease or supraclavicular radiation in the treatment of breast carcinoma; (3) neoplasm: lymphoma extending from the neck or mediastinum, superior sulcus bronchogenic carcinoma, and metastases; (4) traumatic: extrapleural dissection of blood from a ruptured aorta, fractures of the ribs or spine, or hemorrhage due to subclavian line placement; (5) vascular: coarctation of the aorta with dilated collaterals over the apex, fistula between the subclavian artery and vein; and (6) miscellaneous: mediastinal lipomatosis with subcostal fat extending over the apices.

  8. Creep of fibrous composite materials

    DEFF Research Database (Denmark)

    Lilholt, Hans

    1985-01-01

    Models are presented for the creep behaviour of fibrous composite materials with aligned fibres. The models comprise both cases where the fibres remain rigid in a creeping matrix and cases where the fibres are creeping in a creeping matrix. The treatment allows for several contributions to the cr......Models are presented for the creep behaviour of fibrous composite materials with aligned fibres. The models comprise both cases where the fibres remain rigid in a creeping matrix and cases where the fibres are creeping in a creeping matrix. The treatment allows for several contributions...... such as Ni + W-fibres, high temperature materials such as Ni + Ni3Al + Cr3C2-fibres, and medium temperature materials such as Al + SiC-fibres. For the first two systems reasonable consistency is found for the models and the experiments, while for the third system too many unquantified parameters exist...

  9. Mammalian CAP interacts with CAP, CAP2, and actin.

    Science.gov (United States)

    Hubberstey, A; Yu, G; Loewith, R; Lakusta, C; Young, D

    1996-06-01

    We previously identified human CAP, a homolog of the yeast adenylyl cyclase-associated protein. Previous studies suggest that the N-terminal and C-terminal domains of CAP have distinct functions. We have explored the interactions of human CAP with various proteins. First, by performing yeast two-hybrid screens, we have identified peptides from several proteins that interact with the C-terminal and/or the N-terminal domains of human CAP. These peptides include regions derived from CAP and BAT3, a protein with unknown function. We have further shown that MBP fusions with these peptides can associate in vitro with the N-terminal or C-terminal domains of CAP fused to GST. Our observations indicate that CAP contains regions in both the N-terminal and C-terminal domains that are capable of interacting with each other or with themselves. Furthermore, we found that myc-epitope-tagged CAP coimmunoprecipitates with HA-epitope-tagged CAP from either yeast or mammalian cell extracts. Similar results demonstrate that human CAP can also interact with human CAP2. We also show that human CAP interacts with actin, both by the yeast two-hybrid test and by coimmunoprecipitation of epitope-tagged CAP from yeast or mammalian cell extracts. This interaction requires the C-terminal domain of CAP, but not the N-terminal domain. Thus CAP appears to be capable of interacting in vivo with other CAP molecules, CAP2, and actin. We also show that actin co-immunoprecipitates with HA-CAP2 from mammalian cell extracts.

  10. Optic Nerve Decompression for Orbitofrontal Fibrous Dysplasia

    OpenAIRE

    Abe, Takumi; Sato, Kaneshige; Otsuka, Takaharu; Kawamura, Noriyoshi; Shimazu, Motohiko; Izumiyama, Hitoshi; Matsumoto, Kiyoshi

    2002-01-01

    Orbitofrontal fibrous dysplasia often involves the bony orbit and the optic canal. Although fibrous dysplasia reportedly produces compression of the optic nerve leading to visual distrubances, optic nerve decompression in patients without clinical signs of optic neuropathy is still controversial. We describe two patients with orbitofrontal fibrous dysplasia without signs of visual disturbance and one patient with McCune-Albright syndrome and progressive visual impairment. Optic nerve decompre...

  11. Oral benign fibrous histiocytoma: two case reports

    OpenAIRE

    Menditti, Dardo; Laino, Luigi; Mezzogiorno, Antonio; Sava, Sara; Bianchi, Alexander; Caruso, Giovanni; Di Maio, Luigi; Baldi, Alfonso

    2009-01-01

    Fibrous histiocytoma is a benign soft tissue tumour arising as a fibrous mass everywhere in the human body. The involvement of the oral cavity is rare. We report two cases of benign fibrous histiocytoma that localized in the oral cavity. The clinical and histological features of the lesion are reported. Finally, a literature revision of this pathology at the level of the oral cavity is reported.

  12. Heat transfer in Rockwool modelling and method of measurement. Modelling radiative heat transfer in fibrous materials

    Energy Technology Data Exchange (ETDEWEB)

    Dyrboel, Susanne

    1998-05-01

    Fibrous materials are some of the most widely used materials for thermal insulation. In this project the focus of interest has been on fibrous materials for building application. Interest in improving the thermal properties of insulation materials is increasing as legislation is being tightened to reduce the overall energy consumption. A knowledge of the individual heat transfer mechanisms - whereby heat is transferred within a particular material is an essential tool to improve continuously the thermal properties of the material. Heat is transferred in fibrous materials by four different transfer mechanisms: conduction through air, conduction through fibres, thermal radiation and convection. In a particular temperature range the conduction through air can be regarded as a constant, and conduction through fibres is an insignificant part of the total heat transfer. Radiation, however, constitutes 25-40% of the total heat transfer in light fibrous materials. In Denmark and a number of other countries convection in fibrous materials is considered as non-existent when calculating heat transmission as well as when designing building structures. Two heat transfer mechanisms have been the focus of the current project: radiation heat transfer and convection. The radiation analysis serves to develop a model that can be used in further work to gain a wider knowledge of the way in which the morphology of the fibrous material, i.e. fibre diameter distribution, fibre orientation distribution etc., influences the radiation heat transfer under different conditions. The convection investigation serves to examine whether considering convection as non-existent is a fair assumption to use in present and future building structures. The assumption applied in practically is that convection makes a notable difference only in very thick insulation, at external temperatures below -20 deg. C, and at very low densities. For lager thickness dimensions the resulting heat transfer through the

  13. Fibrous histiocytoma of the laryngeal glottis

    Institute of Scientific and Technical Information of China (English)

    GE Pingjiang; ZHANG Baoquan; GAO Zhiqiang; Wang Hui; CUI Quancai

    2005-01-01

    A case of a fibrous histiocytoma (FH) of the larynx in a 54-year-old male is reported. Laryngeal fibrous histiocytoma is uncommon. The case recurred several times over 4-year period. Its pathology is described including arguments on potential malignancy and the way of management.

  14. Solitary Fibrous Tumor of the Stomach

    Science.gov (United States)

    Hussain, Qulsoom; Shafique, Khurram; Hurairah, Abu; Grossman, Evan B.

    2017-01-01

    Solitary fibrous tumor is a rare mesenchymal neoplasm that usually originates from the pleura, but has been reported in other extrapleural locations. We report a rare case of a solitary fibrous tumor of the stomach, which was successfully treated with endoscopic mucosal resection. PMID:28286800

  15. Saltstone Clean Cap Formulation

    Energy Technology Data Exchange (ETDEWEB)

    Langton, C

    2005-04-22

    The current operation strategy for using Saltstone Vault 4 to receive 0.2 Ci/gallon salt solution waste involves pouring a clean grout layer over the radioactive grout prior to initiating pour into another cell. This will minimize the radiating surface area and reduce the dose rate at the vault and surrounding area. The Clean Cap will be used to shield about four feet of Saltstone poured into a Z-Area vault cell prior to moving to another cell. The minimum thickness of the Clean Cap layer will be determined by the cesium concentration and resulting dose levels and it is expected to be about one foot thick based on current calculations for 0.1 Ci Saltstone that is produced in the Saltstone process by stabilization of 0.2 Ci salt solution. This report documents experiments performed to identify a formulation for the Clean Cap. Thermal transient calculations, adiabatic temperature rise measurements, pour height, time between pour calculations and shielding calculations were beyond the scope and time limitations of this study. However, data required for shielding calculations (composition and specific gravity) are provided for shielding calculations. The approach used to design a Clean Cap formulation was to produce a slurry from the reference premix (10/45/45 weight percent cement/slag/fly ash) and domestic water that resembled as closely as possible the properties of the Saltstone slurry. In addition, options were investigated that may offer advantages such as less bleed water and less heat generation. The options with less bleed water required addition of dispersants. The options with lower heat contained more fly ash and less slag. A mix containing 10/45/45 weight percent cement/slag/fly ash with a water to premix ratio of 0.60 is recommended for the Clean Cap. Although this mix may generate more than 3 volume percent standing water (bleed water), it has rheological, mixing and flow properties that are similar to previously processed Saltstone. The recommended

  16. Nutritional fibrous osteodystrophy in goats

    Directory of Open Access Journals (Sweden)

    Paulo M Bandarra

    2011-10-01

    Full Text Available Seven out of 25 goats from a southern Brazilian flock developed nutritional fibrous osteodystrophy. Affected animals were younger than 1 year of age and were confined in stalls and fed a concentrate ration containing 1:6 calcium:phosphorus ratio. The remaining flock (35 goats was managed at pasture and showed no disease. Clinical signs were characterized by mandibular and maxillary enlargements, varying degrees of mouth opening and protruding tongue, dyspnea, apart of abnormalities of prehension and mastication. Affected animals had increased seric levels of phosphorus and parathormone, as well as higher alkaline phosphatase activity. Postmortem examination on three succumbed goats revealed bilateral enlargement of the maxilla and mandibula, and loose teeth, apart of multiple incomplete rib fractures in one of them. Severe diffuse proliferation of loose connective tissue surrounded the osteoid trabeculae, many of which were partially or completely non-mineralized. Mineralized osteoid trabeculae showed osteoclasts in the Howship's lacunae.

  17. Posttraumatic Cranial Cystic Fibrous Dysplasia

    Directory of Open Access Journals (Sweden)

    Arata Tomiyama

    2011-01-01

    Full Text Available A 14-year-old was girl admitted to our hospital with a subcutaneous mass of the occipital head. The mass had grown for 6 years, after she had sustained a head injury at the age of 6, and was located directly under a previous wound. Skull X-ray Photograph (xp, computed tomography (CT, and magnetic resonance imaging (MRI showed a bony defect and cystic changes in the skull corresponding to a subcutaneous mass. Bone scintigraphy revealed partial accumulation. The patient underwent total removal of the skull mass, and the diagnosis from the pathological findings of the cyst wall was fibrous dysplasia (FD. The radiographic findings for cystic cranial FD can be various. Progressive skull disease has been reported to be associated with head trauma, but the relationship between cranial FD and head trauma has not been previously reported. Previous studies have suggested that c-fos gene expression is a key mechanism in injury-induced FD.

  18. Fibrous-Ceramic/Aerogel Composite Insulating Tiles

    Science.gov (United States)

    White, Susan M.; Rasky, Daniel J.

    2004-01-01

    Fibrous-ceramic/aerogel composite tiles have been invented to afford combinations of thermal-insulation and mechanical properties superior to those attainable by making tiles of fibrous ceramics alone or aerogels alone. These lightweight tiles can be tailored to a variety of applications that range from insulating cryogenic tanks to protecting spacecraft against re-entry heating. The advantages and disadvantages of fibrous ceramics and aerogels can be summarized as follows: Tiles made of ceramic fibers are known for mechanical strength, toughness, and machinability. Fibrous ceramic tiles are highly effective as thermal insulators in a vacuum. However, undesirably, the porosity of these materials makes them permeable by gases, so that in the presence of air or other gases, convection and gas-phase conduction contribute to the effective thermal conductivity of the tiles. Other disadvantages of the porosity and permeability of fibrous ceramic tiles arise because gases (e.g., water vapor or cryogenic gases) can condense in pores. This condensation contributes to weight, and in the case of cryogenic systems, the heat of condensation undesirably adds to the heat flowing to the objects that one seeks to keep cold. Moreover, there is a risk of explosion associated with vaporization of previously condensed gas upon reheating. Aerogels offer low permeability, low density, and low thermal conductivity, but are mechanically fragile. The basic idea of the present invention is to exploit the best features of fibrous ceramic tiles and aerogels. In a composite tile according to the invention, the fibrous ceramic serves as a matrix that mechanically supports the aerogel, while the aerogel serves as a low-conductivity, low-permeability filling that closes what would otherwise be the open pores of the fibrous ceramic. Because the aerogel eliminates or at least suppresses permeation by gas, gas-phase conduction, and convection, the thermal conductivity of such a composite even at

  19. Radiation-induced intracranial malignant fibrous histiocytoma

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez-Vitale, J.C.; Slavin, R.E.; McQueen, J.D.

    1976-06-01

    An autopsy case of radiation-induced intracranial malignant fibrous histiocytoma (fibroxanthosarcoma) is reported. The tumor developed in the region of the sella turcica 11 years after high dose radiotherapy of a chromophobe adenoma of the pituitary. The tumor had infiltrated the base of the brain as well as the base of the skull. Metastases were not found. The tumor was composed of an admixture of bizarre fibroblasts, histiocytes and giant cells, xanthoma cells and siderophages, with a storiform fibrous stroma. This appears to be the first documented instance of a malignant fibrous histiocytoma occurring intracranially after local x irradiation.

  20. The "pirate sign" in fibrous dysplasia.

    Science.gov (United States)

    Singnurkar, Amit; Rush, Chris

    2006-11-01

    Fibrous dysplasia commonly involves the skull in both its monostotic and polyostotic variants. We present two cases of fibrous dysplasia involving the sphenoid wing, which were strikingly similar in their bone scan appearance. Both patients demonstrated intense increased uptake of Tc-99m MDP in a pattern reminding us of a "pirate wearing an eyepatch." We propose that this characteristic appearance of fibrous dysplasia of the sphenoid wing be called the "pirate sign." A review of the literature revealed several other pathologic conditions that have been reported to involve the sphenoid bone and should be considered in the differential diagnosis of abnormal bone tracer uptake in this region.

  1. Atypical Cutaneous Fibrous Histiocytoma: An Unusual and Misleading Variant of Fibrous Histiocytoma

    OpenAIRE

    Soumaya Ben Abdelkrim; Colondane Belajouza; Wafa Jomaa; Nadia Beizig; Zeineb Ben Said; Moncef Mokni; Rafia Nouira; Badreddine Sriha

    2011-01-01

    Atypical fibrous histiocytoma is a distinctive variant of cutaneous fibrous histiocytoma, which is often mistaken histologically for sarcoma and which have a tendency to recur locally and a capacity to metastasize, although very rarely. We report a new case of atypical cutaneous fibrous histiocytoma in a 31-year-old man who presented with a recurrent polypoid nodule on the abdominal wall. The diagnosis was made on the basis of morphological and immunohistochemical findings. We discuss through...

  2. Solitary Fibrous Tumor of the Uterus

    Directory of Open Access Journals (Sweden)

    Po-Wei Chu

    2006-12-01

    Conclusion: The behavior of solitary fibrous tumors arising from the uterus is difficult to evaluate; therefore, complete surgical excision featuring clear margins and comprehensive follow-up is recommended.

  3. [Solitary fibrous tumours of the kidney].

    Science.gov (United States)

    Gres, Pascal; Avances, Christophe; Ben Naoum, Kamel; Chapuis, Héliette; Costa, Pierre

    2004-02-01

    Solitary fibrous tumours (SFT) are mesenchymal tumours that usually arise from the pleura. Renal SFT are exceptional (9 cases reported in the literature). The authors report a new case discovered during assessment of HT and treated by radical right nephrectomy. The histological appearance is characteristic: a tumour with a fibrous centre, composed of a monomorphic proliferation of spindle cells, with positive CD 34, CD 99, and bcl 2 labelling. The prognosis after complete resection is generally favourable.

  4. Fibrous dysplasia of bone causing unilateral proptosis

    Directory of Open Access Journals (Sweden)

    Reshma Ramakrishnan

    2015-01-01

    Full Text Available Fibrous dysplasia (FD is a slow growing benign noninherited disorder in which normal bones are replaced by fibrous tissue and immature woven bones. Here we report a case of 30-year-old female who presented with unilateral proptosis and lagophthalmos without any visual loss; was diagnosed with polyostotic FD. Patient was taken up for surgery. Osseous reconturing was done by shaving of involved facial bones. Postoperatively, there was a decrease in proptosis and lagophthalmos.

  5. Fibrous dysplasia of bone: a clinicopathologic review

    Directory of Open Access Journals (Sweden)

    Mohan H

    2011-11-01

    Full Text Available Harsh Mohan1, Preeti Mittal1, Irneet Mundi1, Sudhir Kumar21Department of Pathology, 2Department of Orthopedics, Government Medical College, Sector 32, Chandigarh, IndiaAbstract: Fibrous dysplasia of the bones is an uncommon congenital skeletal disorder that is found equally in both genders and is not inherited. Its etiology has been linked to an activating mutation of Gsα and the downstream effects of the resultant increase in cAMP. Fibrous dysplasia is categorized as either monostotic or polyostotic, and may occur as a component of McCune-Albright syndrome or the rare Mazabraud syndrome. Long bones, skull bones, and ribs are the most commonly affected bones. The radiological picture is somewhat variable, including a ground-glass appearance, expansion of the bone, and sclerosis surrounding the lesion. Histologically, fibrous dysplasia shows irregularly-shaped trabeculae of immature, woven bone in a background of variably cellular, loosely arranged fibrous stroma. It may be complicated by pathologic fracture, and rarely by malignant transformation. This review examines interesting issues surrounding the etiology of fibrous dysplasia, its clinical and laboratory manifestations, radiological picture, utility of bone biopsy, gross and microscopic pathology, complications, and its differential diagnostic considerations.Keywords: fibrous dysplasia, McCune-Albright syndrome, monostotic form, polyostotic form

  6. The cervical cap (image)

    Science.gov (United States)

    The cervical cap is a flexible rubber cup-like device that is filled with spermicide and self-inserted over the cervix ... left in place several hours after intercourse. The cap is a prescribed device fitted by a health ...

  7. Fibrous osteodystrophy in two Northern Royal albatross chicks (Diomedea sanfordi).

    Science.gov (United States)

    Morgan, K J; Alley, M R; Gartrell, B D; Thompson, K G; Perriman, L

    2011-09-01

    In February 2004, two Northern Royal albatross chicks aged 20 and 25 days old were presented for necropsy. Both chicks had been hand-fed in situ at a breeding colony, from 2-3 days post-hatch. The hand-rearing diet consisted of boneless hoki fillets (Macraronus novaezelandiae), electrolytes, and sooty shearwater (Puffinus griseus) proventricular oil obtained as a by-product of cultural harvest. Routine necropsies on the affected chicks revealed many bones were soft and easily bent. Radiography and histopathology revealed decreased bone density, pathological fractures, and extensive remodelling suggestive of fibrous osteodystrophy. Nutritional secondary hyperparathyroidism, resulting from an imbalance in the dietary Ca:P ratio. The imbalance in the dietary Ca:P ratio was a result of feeding deboned and eviscerated fish. This investigation also highlighted potential health risks associated with the practice of feeding stored rancid proventricular oil, including the destruction of fat-soluble vitamins. It is therefore possible that oxidative degradation of vitamin D may have contributed to the development of nutritional secondary hyperparathyroidism. Subsequently, dietary recommendations for supplementary feeding of orphaned Northern Royal albatross chicks include the feeding of whole human-grade fish with an appropriate Ca:P ratio, and the exclusion of proventricular oil. These cases highlight the need for scientific input into wildlife conservation projects, as lack of appropriate nutritional advice resulted in the feeding of a nutritionally inadequate diet. Following the recommended changes in diet, no further cases of osteodystrophy have been diagnosed in hand-raised chicks in the albatross colony.

  8. Polar Cap Patch Dynamics

    Science.gov (United States)

    2013-04-25

    cap arcs Citation: Hosokawa, K., J. I. Moen, K. Shiokawa, and Y. Otsuka ( 2011 ), Motion of polar cap arcs , J. Geophys. Res. , 116 , A01305, doi...K., J. I. Moen, K. Shiokawa, and Y. Otsuka , (2011), Decay of polar cap patch, J. Geophys. Res., 116, A05308, doi:10.1029/2010JA016287, Abstract. We

  9. Cradle Cap: Treatment

    Science.gov (United States)

    Cradle cap Treatment Cradle cap usually doesn't require medical treatment. It clears up on its own within a few months. In the meantime, wash ... tips can help you control and manage cradle cap. Gently rub your baby's scalp with your fingers ...

  10. PIV-based investigation of the skin friction of the flow over random fibrous media

    Science.gov (United States)

    Mirbod, Parisa; Gheisari, Reza

    2015-11-01

    Finite Reynolds number (Reflow over fibrous medium inside a rectangular duct was studied using a planar 2D PIV system. Three different fibrous materials with different porosities were used. Fibrous material lined the bottom wall of the duct along the length of the duct. The flow regime for all tests was laminar, and measurements were all done when the flow reached a steady state. Error and uncertainty sources in the experiments were also discussed. Shear rates were estimated at the surface of the fibrous media. As a conclusion to this study skin friction factor were calculated at the interface of all fibrous media at selected Reynolds number. Then using power function, curve fits with the Cf = a/Re form were found which could closely correlate skin friction and Reynolds number. To weaken the effect of near-wall errors in estimated shear rates and consequently skin friction, an average of shear rate estimation in a layer with thickness of 5 mm was calculated which was used to calculate an average skin friction. Correlations of average skin friction with average Reynolds number were also presented.

  11. Fibrous Dysplasia Characterization Using Lacunarity Analysis.

    Science.gov (United States)

    Cordeiro, Mirna S; Backes, André R; Júnior, Antônio F Durighetto; Gonçalves, Elmar H G; de Oliveira, Jefferson X

    2016-02-01

    Fibrous dysplasia (FD) is a developmental anomaly in which the normal medullary space of the affected bone is replaced by fibro-osseous tissue. This condition is typically encountered in adolescents and young adults. It affects the maxillofacial region and it can often cause severe deformity and asymmetry. Therefore, accurate diagnosis is critical to determine the appropriate treatment of each case. In this sense, computed tomography (CT) is a relevant resource among the imaging techniques for correct diagnosis of this condition. Thus, in this paper, we propose to analyze fibrous dysplasia through its texture pattern. To accomplish this task, we propose to use lacunarity analysis, a multiscale method for describing patterns of spatial dispersion. Results indicated lower lacunarity values for fibrous dysplasia in comparison to normal bone samples, an indication that their texture images are more homogeneous, and a high separability between the classes when using principal component analysis (PCA) and decision trees for statistical analysis.

  12. Congenital fibrous hamartoma of the knee

    Energy Technology Data Exchange (ETDEWEB)

    Arioni, Cesare; Bellini, Carlo; Risso, Francesco Maria; Scopesi, Fabio; Serra, Giovanni [University of Genoa, Neonatal Pathology Service, Department of Paediatrics, Institute G. Gaslini, Genoa (Italy); Oddone, Mauro; Toma, Paolo [Institute G. Gaslini, Radiology Service, Genoa (Italy); Nozza, Paolo [Institute G. Gaslini, U. O. di Anatomia Patologica, Genoa (Italy)

    2006-05-15

    A full-term male infant presented at birth with a hard swelling of the left knee. The lemon-sized lesion was fixed to the underlying knee muscles, while the overlying skin was stretched and shiny; there was no bruit. Radiography, sonography and MRI suggested a soft-tissue tumour. After surgical excision, histology showed the presence of fibrous and mesenchymal tissue, with mature adipose tissue. Fibrous hamartoma of infancy was diagnosed. Among soft-tissue tumours, fibrous hamartoma of infancy is a rare and benign lesion, occurring in the first 2 years of life. The tumour mainly affects the trunk, axilla, and upper extremities. This infant had unique involvement of the knee. The treatment of choice is local excision. (orig.)

  13. Malignant fibrous histiocytoma with skeletal involvement

    Directory of Open Access Journals (Sweden)

    Takechi,Hideo

    1978-10-01

    Full Text Available Malignant fibrous histiocytoma of soft part is rather common but malignant fibrous histiocytoma of the bone is rarely encountered clinically. Authors present five cases of malignant fibrous histiocytoma with skeletal involvement and discuss their clinical course, x-ray findings and histological features. This tumor has marked tendency for local recurrence and metastasis. Other bone tumors such as giant cell tumor, aneurysmal bone cyst, non ossifying fibroma, osteosarcoma, fibrosarcoma of bone and metastatic cancer can be excluded by several characteristic findings observed in x-rays as well as histopathological features. All information on the patient should be carefully analysed, because it is difficult to decide whether bone involvement is primary or secondary. Four out of five cases definitely originated within the bone.

  14. Heat transfer in Rockwool modelling and method of measurement. The effect of natural convection on heat transfer in fibrous materials

    Energy Technology Data Exchange (ETDEWEB)

    Dyrboel, Susanne

    1998-05-01

    Fibrous materials are some of the most widely used materials for thermal insulation. In this project the focus of interest has been on fibrous materials for building application. Interest in improving the thermal properties of insulation materials is increasing as legislation is being tightened to reduce the overall energy consumption. A knowledge of the individual heat transfer mechanisms - whereby heat is transferred within a particular material is an essential tool to improve continuously the thermal properties of the material. Heat is transferred in fibrous materials by four different transfer mechanisms: conduction through air, conduction through fibres, thermal radiation and convection. In a particular temperature range the conduction through air can be regarded as a constant, and conduction through fibres is an insignificant part of the total heat transfer. Radiation, however, constitutes 25-40% of the total heat transfer in light fibrous materials. In Denmark and a number of other countries convection in fibrous materials is considered as non-existent when calculating heat transmission as well as when designing building structures. Two heat transfer mechanisms have been the focus of the current project: radiation heat transfer and convection. The radiation analysis serves to develop a model that can be used in further work to gain a wider knowledge of the way in which the morphology of the fibrous material, i.e. fibre diameter distribution, fibre orientation distribution etc., influences the radiation heat transfer under different conditions. The convection investigation serves to examine whether considering convection as non-existent is a fair assumption to use in present and future building structures. The assumption applied in practically is that convection makes a notable difference only in very thick insulation, at external temperatures below -20 deg. C, and at very low densities. For large thickness dimensions the resulting heat transfer through the

  15. Phosphogypsum capping depth affects revegetation and hydrology in Western Canada.

    Science.gov (United States)

    Jackson, Mallory E; Naeth, M Anne; Chanasyk, David S; Nichol, Connie K

    2011-01-01

    Phosphogypsum (PG), a byproduct of phosphate fertilizer manufacturing, is commonly stacked and capped with soil at decommissioning. Shallow (0, 8, 15, and 30 cm) and thick (46 and 91 cm) sandy loam caps on a PG stack near Fort Saskatchewan, Alberta, Canada, were studied in relation to vegetation establishment and hydrologic properties. Plant response was evaluated over two growing seasons for redtop ( L.), slender wheatgrass ( (Link) Malte ex H.F. Lewis), tufted hairgrass ( (L.) P. Beauv.), and sheep fescue ( L.) and for a mix of these grasses with alsike clover ( L.). Water content below the soil-PG interface was monitored with time-domain reflectometry probes, and leachate water quantity and quality at a depth of 30 cm was measured using lysimeters. Vegetation responded positively to all cap depths relative to bare PG, with few significant differences among cap depths. Slender wheatgrass performed best, and tufted hairgrass performed poorly. Soil caps <1 m required by regulation were sufficient for early revegetation. Soil water fluctuated more in shallow than in thick caps, and water content was generally between field capacity and wilting point regardless of cap depth. Water quality was not affected by cap depths ≤30 cm. Leachate volumes at 30 cm from distinct rainfall events were independent of precipitation amount and cap depth. The study period had lower precipitation than normal, yet soil caps were hospitable for plant growth in the first 2 yr of establishment.

  16. Fibrous Protein Structures: Hierarchy, History and Heroes.

    Science.gov (United States)

    Squire, John M; Parry, David A D

    2017-01-01

    During the 1930s and 1940s the technique of X-ray diffraction was applied widely by William Astbury and his colleagues to a number of naturally-occurring fibrous materials. On the basis of the diffraction patterns obtained, he observed that the structure of each of the fibres was dominated by one of a small number of different types of molecular conformation. One group of fibres, known as the k-m-e-f group of proteins (keratin - myosin - epidermin - fibrinogen), gave rise to diffraction characteristics that became known as the α-pattern. Others, such as those from a number of silks, gave rise to a different pattern - the β-pattern, while connective tissues yielded a third unique set of diffraction characteristics. At the time of Astbury's work, the structures of these materials were unknown, though the spacings of the main X-ray reflections gave an idea of the axial repeats and the lateral packing distances. In a breakthrough in the early 1950s, the basic structures of all of these fibrous proteins were determined. It was found that the long protein chains, composed of strings of amino acids, could be folded up in a systematic manner to generate a limited number of structures that were consistent with the X-ray data. The most important of these were known as the α-helix, the β-sheet, and the collagen triple helix. These studies provided information about the basic building blocks of all proteins, both fibrous and globular. They did not, however, provide detailed information about how these molecules packed together in three-dimensions to generate the fibres found in vivo. A number of possible packing arrangements were subsequently deduced from the X-ray diffraction and other data, but it is only in the last few years, through the continued improvements of electron microscopy, that the packing details within some fibrous proteins can now be seen directly. Here we outline briefly some of the milestones in fibrous protein structure determination, the role of the

  17. Enzymes in bast fibrous plant processing.

    Science.gov (United States)

    Kozlowski, Ryszard; Batog, Jolanta; Konczewicz, Wanda; Mackiewicz-Talarczyk, Maria; Muzyczek, Malgorzata; Sedelnik, Natalia; Tanska, Bogumila

    2006-05-01

    The program COST Action 847 Textile Quality and Biotechnology (2000-2005) has given an excellent chance to review the possibilities of the research, aiming at development of the industrial application of enzymes for bast fibrous plant degumming and primary processing. The recent advancements in enzymatic processing of bast fibrous plants (flax, hemp, jute, ramie and alike plants) and related textiles are given. The performance of enzymes in degumming, modification of bast fibres, roving, yarn, related fabrics as well as enzymatic bonding of lignocellulosic composites is provided.

  18. A case of intracranial malignant fibrous histiocytoma

    Directory of Open Access Journals (Sweden)

    Amir Hossein Sarrami

    2011-01-01

    Full Text Available We describe a case of intracranial malignant fibrous histiocytoma which had infiltrated pons, cerebellum and basal surface of left temporal lobe without any visible mass. The patient presented with a sudden loss of consciousness and vomiting. Clinical findings, laboratory tests, imaging and examination of the cerebrospinal fluid tended to establish the diagnosis of an infectious condition than a malignancy. Without any response to the antibiotics and with a progressive deterioration of neurologic and mental condition, the patient died after 20 days. In the autopsy, histological and immunohistochemical study of the brain revealed the diagnosis of malignant fibrous histiocytoma (MFH.

  19. Atypical cutaneous fibrous histiocytoma: an unusual and misleading variant of fibrous histiocytoma.

    Science.gov (United States)

    Ben Abdelkrim, Soumaya; Belajouza, Colondane; Jomaa, Wafa; Beizig, Nadia; Ben Said, Zeineb; Mokni, Moncef; Nouira, Rafia; Sriha, Badreddine

    2011-01-01

    Atypical fibrous histiocytoma is a distinctive variant of cutaneous fibrous histiocytoma, which is often mistaken histologically for sarcoma and which have a tendency to recur locally and a capacity to metastasize, although very rarely. We report a new case of atypical cutaneous fibrous histiocytoma in a 31-year-old man who presented with a recurrent polypoid nodule on the abdominal wall. The diagnosis was made on the basis of morphological and immunohistochemical findings. We discuss through this case and a review of the literature pathological and evolutive features and diagnostic difficulties of this entity.

  20. Atypical Cutaneous Fibrous Histiocytoma: An Unusual and Misleading Variant of Fibrous Histiocytoma

    Directory of Open Access Journals (Sweden)

    Soumaya Ben Abdelkrim

    2011-01-01

    Full Text Available Atypical fibrous histiocytoma is a distinctive variant of cutaneous fibrous histiocytoma, which is often mistaken histologically for sarcoma and which have a tendency to recur locally and a capacity to metastasize, although very rarely. We report a new case of atypical cutaneous fibrous histiocytoma in a 31-year-old man who presented with a recurrent polypoid nodule on the abdominal wall. The diagnosis was made on the basis of morphological and immunohistochemical findings. We discuss through this case and a review of the literature pathological and evolutive features and diagnostic difficulties of this entity.

  1. Calcifying fibrous pseudotumor of pleura: radiologic features in three cases.

    Science.gov (United States)

    Erasmus, J J; McAdams, H P; Patz, E F; Murray, J G; Pinkard, N B

    1996-01-01

    Our goal was to describe the radiologic features of calcifying fibrous pseudotumor (CEPT) of pleura. Chest radiographs and CT images of three patients, aged 23-34 years, with pathologically proven CFPT of pleura were reviewed with regard to lesion size, location, and appearance. Chest radiographs showed well marginated, noncalcified pleural masses in all cases. Two patients had solitary masses and one had multifocal ipsilateral masses. All masses were located in the inferior aspect of the chest and measured 3-12 cm. All masses were calcified on CT. The calcifications were thick and band-like in two cases and punctate in one. There was no chest wall invasion, pleural effusion, or parenchymal disease. CFPTs of pleura are rare lesions that manifest as calcified pleural masses in young adults.

  2. An Empirical Formula for Sound Absorption of Fibrous Materials

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xin-an

    2008-01-01

    The sound absorption coefficient (SAC) curves of the nonwovens, fabrics, and thick fibrous layers with the frequency in the range of 125-3 200 Hz and cavity distances of 5 cm, 10 cm, 20 cm, 30 cm and 40 cm were measured.Based on analysis, it is found that the SAC is actually in direct proportion to the relative vibration amplitude of the sound wave, resulting in obtaining a mathematical expression showing that the SAC changes with the frequency for a given material. Additionally, a good corresponding relation between the maximal SAC and the permeability of the materials is discovered, thus an empirical formula is established. As a result, a complete SAC formula has been developed. In this formula, the SAC is solely a function of the sound wave frequency and permeability of the material. In comparison with sound absorption spectra of several materials, the calculated results and results measured with the formula coincide well with each other.

  3. Clinicopathologic characteristics of fibrous mass-forming chronic pancreatitis

    Institute of Scientific and Technical Information of China (English)

    常雪姣

    2013-01-01

    Objective To investigate clinicopathological features of fibrous mass-forming chronic pancreatitis (FMCP) ,to compare clinicopathological and immunohistochemical characteristics between autoimmune pancreatitis (AIP) and fibrous mass-forming non-autoimmune pancreatitis

  4. Cervical spinal monostotic fibrous dysplasia: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ok Hwa [Dept. of Radiology, Haeundae Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of)

    2013-09-15

    Monostotic fibrous dysplasia of the cervical vertebra is quite unusual. The author reports a case of monostotic fibrous dysplasia affecting the second cervical vertebra with descriptions from the CT, MR and bone scanning findings.

  5. Optic nerve decompression for orbitofrontal fibrous dysplasia.

    Science.gov (United States)

    Abe, Takumi; Sato, Kaneshige; Otsuka, Takaharu; Kawamura, Noriyoshi; Shimazu, Motohiko; Izumiyama, Hitoshi; Matsumoto, Kiyoshi

    2002-08-01

    Orbitofrontal fibrous dysplasia often involves the bony orbit and the optic canal. Although fibrous dysplasia reportedly produces compression of the optic nerve leading to visual distrubances, optic nerve decompression in patients without clinical signs of optic neuropathy is still controversial. We describe two patients with orbitofrontal fibrous dysplasia without signs of visual disturbance and one patient with McCune-Albright syndrome and progressive visual impairment. Optic nerve decompression was performed prophylactically for two patients and therapeutically for one patient through the transcranial extradural route. Dystopias and craniofacial deformities induced by fibrous dysplasia also were corrected. The micropressure suction-irrigation system was especially effective for decreasing heat transfer and thereby preventing thermal injury of the optic nerve. The orbitofrontal area was reconstructed from cranial bone, iliac bone, and ribs. Postoperative follow-up revealed no disturbances in visual function and no evidence of cerebrospinal fluid leakage. These findings suggest that optic nerve decompression may be effective in preventing visual disturbances with minimal risk of other neurological sequelae. Subsequent orbital reconstruction yielded satisfactory cosmetic results.

  6. Prophylactic intramedullary nailing in monostotic fibrous dysplasia.

    Science.gov (United States)

    Demiralp, Bahtiyar; Ozturk, Cagatay; Ozturan, Kutay; Sanisoglu, Yavuz S; Cicek, Ilker E; Erler, Kaan

    2008-06-01

    Fibrous dysplasia of bone is an enigma with no known cure. Treatment currently consists of curettage and bone-grafting in an attempt to eradicate the lesion and to prevent progressive deformity. This study presents the results of prophylactic intramedullary nailing in 10 patients with monostotic fibrous dysplasia, pain increasing with movement, and scintigraphically established activity. Ten patients with monostotic fibrous dysplasia in their upper or lower extremities treated between 2001 and 2003 were included in the study. Seven patients were male and 3 were female; their mean age was 26.9 years. The mean duration of follow-up was 33.5 months. Closed intramedullary nail without reaming was used in all cases. Bone grafting was not performed. Patients were allowed full weight bearing on the affected extremities on the second postoperative day. Mean VAS for functional pain was 5.33 +/- 0.65 preoperatively and 2.26 +/- 0.57 at final follow-up (p < 0.05). Radiographs showed no changes in lesion size, and the intramedullary fixation appeared to be stable. Prophylactic intramedullary nailing appeared to be beneficial in monostotic fibrous dysplasia with scintigraphically proven activity and functional pain. It also avoids problems that may occur following pathological fracture.

  7. Giant solitary fibrous tumour of the liver

    NARCIS (Netherlands)

    T. Terkivatan (Türkan); M. Kliffen (Mike); J.H.W. de Wilt (Johannes); A.N. van Geel (Albert); A.M.M. Eggermont (Alexander); C. Verhoef (Kees)

    2006-01-01

    textabstractBackground: Solitary fibrous tumour (SFT) is an uncommon mesenchymal neoplasm that most frequently affects the pleura, although it has been reported with increasing frequency in various other sites such as in the peritoneum, pericardium and in non-serosal sites such as lung parenchyma,

  8. Craniofacial fibrous dysplasia: A 10-case series.

    Science.gov (United States)

    Couturier, A; Aumaître, O; Gilain, L; Jean, B; Mom, T; André, M

    2017-09-01

    Fibrous dysplasia of bone is a rare sporadic benign congenital condition in which normal cancellous bone is replaced by fibro-osseous tissue with immature osteogenesis. Sarcomatous transformation is exceptional. Lesions may involve one bone (monostotic) or several (polyostotic). Fibrous dysplasia may be associated with café-au-lait skin macules and endocrinopathy in McCune-Albright syndrome, or with myxoma in Mazabraud's syndrome. We report ten cases of patients followed up for craniofacial fibrous dysplasia in our center between 2010 and 2015. Mean age was 43 years (range, 10-72 years). Clinical symptoms comprised headache (n=3) and sensorineural disorder: recurrent anterior uveitis (n=1), visual acuity loss, epiphora and vestibular syndrome (n=1), and hearing loss (n=1). All cases were monostotic. The sphenoid bone was most commonly involved (n=5), followed by the ethmoid (n=1), frontal (n=1), fronto-ethmoid (n=1), temporal (n=1) and fronto-ethmoido-sphenoid (n=1) bones. Five patients were treated with intravenous pamidronate, a bisphosphonate: evolution was favorable for 3 of them at 1-6 months after treatment initiation, with resolution of headache or vestibular syndrome; the other 2 patients were stable. Two patients were operated on. Diagnosis of craniofacial fibrous dysplasia should be considered in case of headache, neuralgia, sensory disorder, functional disorder or infectious ENT complications. A medico-surgical approach is useful for these patients. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  9. Solitary fibrous tumour of the vagus nerve.

    Science.gov (United States)

    Scholsem, Martin; Scholtes, Felix

    2012-04-01

    We describe the complete removal of a foramen magnum solitary fibrous tumour in a 36-year-old woman. It originated on a caudal vagus nerve rootlet, classically described as the 'cranial' accessory nerve root. This ninth case of immunohistologically confirmed cranial or spinal nerve SFT is the first of the vagus nerve.

  10. Combined Heat Transfer in High-Porosity High-Temperature Fibrous Insulations: Theory and Experimental Validation

    Science.gov (United States)

    Daryabeigi, Kamran; Cunnington, George R.; Miller, Steve D.; Knutson, Jeffry R.

    2010-01-01

    Combined radiation and conduction heat transfer through various high-temperature, high-porosity, unbonded (loose) fibrous insulations was modeled based on first principles. The diffusion approximation was used for modeling the radiation component of heat transfer in the optically thick insulations. The relevant parameters needed for the heat transfer model were derived from experimental data. Semi-empirical formulations were used to model the solid conduction contribution of heat transfer in fibrous insulations with the relevant parameters inferred from thermal conductivity measurements at cryogenic temperatures in a vacuum. The specific extinction coefficient for radiation heat transfer was obtained from high-temperature steady-state thermal measurements with large temperature gradients maintained across the sample thickness in a vacuum. Standard gas conduction modeling was used in the heat transfer formulation. This heat transfer modeling methodology was applied to silica, two types of alumina, and a zirconia-based fibrous insulation, and to a variation of opacified fibrous insulation (OFI). OFI is a class of insulations manufactured by embedding efficient ceramic opacifiers in various unbonded fibrous insulations to significantly attenuate the radiation component of heat transfer. The heat transfer modeling methodology was validated by comparison with more rigorous analytical solutions and with standard thermal conductivity measurements. The validated heat transfer model is applicable to various densities of these high-porosity insulations as long as the fiber properties are the same (index of refraction, size distribution, orientation, and length). Furthermore, the heat transfer data for these insulations can be obtained at any static pressure in any working gas environment without the need to perform tests in various gases at various pressures.

  11. Synthesis of Leishmania cap-4 intermediates, cap-2 and cap-3.

    Science.gov (United States)

    Lewdorowicz, Magdalena; Stepinski, Janusz; Kierzek, Ryszard; Jemielity, Jacek; Zuberek, Joanna; Yoffe, Yael; Shapira, Michal; Stolarski, Ryszard; Darzynkiewicz, Edward

    2007-01-01

    Synthesis of Leishmania mRNA 5'-cap analogs, m(7)Gpppm(2)(6)AmpAm (cap-2), and m(7)Gpppm(2)(6)AmpAmpCm (cap-3) is reported. Binding affinities of those cap analogs for LeishIF4E proteins were determined using fluorescence spectroscopy. Cap-3 showed similar affinity to LeishIF4Es compared to the mature trypanosomatids cap structure (cap-4).

  12. Microtubule's conformational cap

    DEFF Research Database (Denmark)

    Chretien, D.; Janosi, I.; Taveau, J.C.

    1999-01-01

    The molecular mechanisms that allow elongation of the unstable microtubule lattice remain unclear. It is usually thought that the GDP-liganded tubulin lattice is capped by a small layer of GTP- or GDP-P(i)-liganded molecules, the so called "GTP-cap". Here, we point-out that the elastic properties...

  13. POROSITY CALCULATION OF MIXTURES OF FIBROUS PARTICLES

    Institute of Scientific and Technical Information of China (English)

    Ruping Zou; Aibing Yu

    2003-01-01

    The initial forming of fiber blend to high green density, i.e. the packing of fibrous particles, is important to the reinforcement of composite materials. It is very useful to develop a general predictive method for the optimum selection of particle mixtures for the property control of ceramic or composite products. This paper presents such a mathematical model developed on the basis of the similarity analysis between the spherical and non-spherical particle packings and assesses its applicability to the packing of fibrous particles with discrete and/or continuous length distributions. The results indicate that the model can predict this packing system well and hence provide an effective way to solve various packing problems in the composite materials processing.

  14. Protease-degradable electrospun fibrous hydrogels

    Science.gov (United States)

    Wade, Ryan J.; Bassin, Ethan J.; Rodell, Christopher B.; Burdick, Jason A.

    2015-03-01

    Electrospun nanofibres are promising in biomedical applications to replicate features of the natural extracellular matrix (ECM). However, nearly all electrospun scaffolds are either non-degradable or degrade hydrolytically, whereas natural ECM degrades proteolytically, often through matrix metalloproteinases. Here we synthesize reactive macromers that contain protease-cleavable and fluorescent peptides and are able to form both isotropic hydrogels and electrospun fibrous hydrogels through a photoinitiated polymerization. These biomimetic scaffolds are susceptible to protease-mediated cleavage in vitro in a protease dose-dependent manner and in vivo in a subcutaneous mouse model using transdermal fluorescent imaging to monitor degradation. Importantly, materials containing an alternate and non-protease-cleavable peptide sequence are stable in both in vitro and in vivo settings. To illustrate the specificity in degradation, scaffolds with mixed fibre populations support selective fibre degradation based on individual fibre degradability. Overall, this represents a novel biomimetic approach to generate protease-sensitive fibrous scaffolds for biomedical applications.

  15. Nonlinear mechanics of soft fibrous materials

    CERN Document Server

    Ogden, Raymond

    2015-01-01

    The book presents a state-of-the-art overview of the fundamental theories, established models and ongoing research related to the modeling of these materials. Two approaches are conventionally used to develop constitutive relations for highly deformable fibrous materials. According to the phenomenological approach, a strain energy density function can be defined in terms of strain invariants. The other approach is based on kinetic theories, which treats a fibrous material as a randomly oriented inter-tangled network of long molecular chains bridged by permanent and temporary junctions. At the micro-level, these are associated with chemical crosslinks and active entanglements, respectively. The papers include carefully crafted overviews of the fundamental formulation of the three-dimensional theory from several points of view, and address their equivalences and differences. Also included are solutions to boundary-value problems which are amenable to experimental verification. A further aspect is the elasticity...

  16. First description of Phanerozoic radiaxial fibrous dolomite

    Science.gov (United States)

    Richter, D. K.; Heinrich, F.; Geske, A.; Neuser, R. D.; Gies, H.; Immenhauser, A.

    2014-05-01

    The petrographic analysis and crystallographic analysis of concretionary carbonate cements ("coal balls") from Carboniferous paralic swamp deposits reveal the presence of (length fast) radiaxial fibrous dolomite (RFD), a fabric not previously reported from the Phanerozoic. This finding is of significance as earlier reports of Phanerozoic radiaxial fibrous carbonates are exclusively of calcite mineralogy. Dolomite concretions described here formed beneath marine transgressive intervals within palustrine coal seams. This is of significance as seawater was arguably the main source of Mg2 + ions for dolomite formation. Here, data from optical microscopy, cathodoluminescence, electron backscattered diffraction, X-ray diffraction and geochemical analyses are presented to characterize three paragenetic dolomite phases and one calcite phase in these concretions. The main focus is on the earliest diagenetic, non-stoichiometric (degree of order: 0.41-0.46) phase I, characterized by botryoidal dolomite constructed of fibres up to 110 μm wide with a systematic undulatory extinction and converging crystal axes. Petrographic and crystallographic evidence clearly qualifies phase I dolomite as radiaxial fibrous. Conversely, fascicular optical fabrics were not found. Carbon-isotope ratios (δ13C) are depleted (between - 11.8 and - 22.1‰) as expected for carbonate precipitation from marine pore-fluids in organic-matter-rich, paralic sediment. Oxygen isotope (δ18O) ratios range between - 1.3 and - 6.0‰. The earliest diagenetic nature of these cements is documented by the presence of ubiquitous, non-compacted fossil plant remains encased in phase I dolomite as well as by the complex zoned luminescence patterns in the crystals and is supported by crystallographic and thermodynamic considerations. It is argued that organic matter, and specifically carboxyl groups, reduced thermodynamic barriers for dolomite formation and facilitated Mg/CaCO3 precipitation. The data shown here

  17. High surface area fibrous silica nanoparticles

    KAUST Repository

    Polshettiwar, Vivek

    2014-11-11

    Disclosed are high surface area nanoparticles that have a fibrous morphology. The nanoparticles have a plurality of fibers, wherein each fiber is in contact with one other fiber and each fiber has a length of between about 1 nm and about 5000 nm. Also disclosed are applications of the nanoparticles of the present invention, and methods of fabrication of the nanoparticles of the present invention.

  18. Monostotic fibrous dysplasia with Raynaud's phenomenon.

    Science.gov (United States)

    Kumar, K V S Hari; Aravinda, K; Narayanan, K

    2015-01-01

    Fibrous dysplasia (FD) is a benign bone disorder characterized by alteration in bone morphology. Monostotic FD is the commonest variant and affects the craniofacial bones. Raynaud's phenomenon is recurrent vasospasm of the fingers and toes due to cold exposure. The disease is usually idiopathic or secondary to connective tissue disorders. Raynaud's phenomenon is not described previously with FD. We recently encountered two interesting patients of craniofacial monostotic FD with Raynaud's phenomenon and report the same in this report.

  19. Malignant fibrous histiocytoma of the abdominal wall

    OpenAIRE

    Arif Aslaner; Burhan Mayir; Tuğrul Çakır; Umut Rıza Gündüz; Nurullah Bülbüller

    2015-01-01

    Malignant fibrous histiocytoma (MFH) or undifferentiated pleomorphic sarcoma is a type of malignt neoplasm that arises from any soft tissue and bone involving extremities, abdomen and retroperitoneum. MFH of the external oblique abdominis muscle is rare. Surgical resection of the mass is the treatment of choice depending on the stage of the disease and the invasion depth of the tumor. Radiotherapy, chemotherapy and immunotherapy are the other treatment methods. We present a case of a 71-year ...

  20. A Case of Extensive polyostotic fibrous dysplasia

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Do [Dept. of Oral and Maxillofacial Radiology, School of Dentistry, Wonkwang University, Iksan (Korea, Republic of); Hwang, Eui Hwan; Lee, Sang Rae [Dept. of Oral and Maxillofacial Radiology, School of Dentistry, Kyunghee University, Seoul (Korea, Republic of)

    2000-06-15

    Fibrous dysplasia is a benign disorder of bone consisting of intramedullary proliferation of fibrous tissue and irregularly distributed, poorly developed bone. The disease manifests itself in the monostotic form in which only one bone is involved and the polyostotic form in which multiple bones at different sites are affected. We reported a extensive case of polyostotic fibrous dysplasia with involvement of craniofacial bones, mandible, ribs, extremities. A 18-year-old man showed remarkable right facial swelling who had been treated on right femur 3 years ago with a bone graft for pathologic fracture and he recognized facial swelling 5 years ago. Extraoral radiograms and computed tomogram showed diffuse sclerosis with a ground glass appearance of the most calvarial bones, facial bones. The right mandibular lesion showed very expansible lesion with mottled appearance. Bone scans showed multifocal increased uptakes in craniofacial bones, right mandible, bilaterally in ribs, humerus, femur, tibia and characteristic various deformity of right femur (shepherd's crook deformity). This case showed exceptionally bilateral, extensive nature of bone lesion and didn't show any features of skin pigmentation and endocrine disturbances.

  1. Toxicity and Carcinogenicity Mechanisms of Fibrous Antigorite

    Directory of Open Access Journals (Sweden)

    Michael Balazy

    2007-03-01

    Full Text Available We studied the effects of fibrous antigorite on mesothelial MeT-5A and monocyte-macrophage J774 cell lines to further understand cellular mechanisms induced by asbestos fibers leading to lung damage and cancer. Antigorite is a mineral with asbestiform properties, which tends to associate with chrysotile or tremolite, and frequently occurs as the predominant mineral in the veins of several serpentinite rocks found abundantly in the Western Alps. Particles containing antigorite are more abundant in the breathing air of this region than those typically found in urban ambient air. Exposure of MeT-5A and J774 cells to fibrous antigorite at concentrations of 5-100 μg/ml for 72 hr induced dose-dependent cytotoxicity. Antigorite also stimulated the ROS production, induced the generation of nitrite and PGE2. MeT-5A cells were more sensitive to antigorite than J774 cells. The results of this study revealed that the fibrous antigorite stimulates cyclooxygenase and formation of hydroxyl and nitric oxide radicals. These changes represent early cellular responses to antigorite fibers, which lead to a host of pathological and neoplastic conditions because free radicals and PGE2 play important roles as mediators of tumor pathogenesis. Understanding the mechanisms of the cellular responses to antigorite and other asbestos particles should be helpful in designing rational prevention and treatment approaches.

  2. Fibrous zinc anodes for high power batteries

    Science.gov (United States)

    Zhang, X. Gregory

    This paper introduces newly developed solid zinc anodes using fibrous material for high power applications in alkaline and large size zinc-air battery systems. The improved performance of the anodes in these two battery systems is demonstrated. The possibilities for control of electrode porosity and for anode/battery design using fibrous materials are discussed in light of experimental data. Because of its mechanical integrity and connectivity, the fibrous solid anode has good electrical conductivity, mechanical stability, and design flexibility for controlling mass distribution, porosity and effective surface area. Experimental data indicated that alkaline cells made of such anodes can have a larger capacity at high discharging currents than commercially available cells. It showed even greater improvement over commercial cells with a non-conventional cell design. Large capacity anodes for a zinc-air battery have also been made and have shown excellent material utilization at various discharge rates. The zinc-air battery was used to power an electric bicycle and demonstrated good results.

  3. Cradle Cap (For Parents)

    Science.gov (United States)

    ... is the common term for seborrheic dermatitis , or seborrhea, which is called dandruff in older kids and ... another factor in the development of cradle cap. Seborrhea happens most often in babies and teenagers. In ...

  4. Fibrous Platinum-Group Minerals in “Floating Chromitites” from the Loma Larga Ni-Laterite Deposit, Dominican Republic

    Directory of Open Access Journals (Sweden)

    Thomas Aiglsperger

    2016-11-01

    Full Text Available This contribution reports on the observation of enigmatic fibrous platinum-group minerals (PGM found within a chromitite body included in limonite (“floating chromitite” from Ni-laterites in the Dominican Republic. Fibrous PGM have a Ru-Os-Ir-Fe dominated composition and are characterized by fibrous textures explained by grain-forming fibers which are significantly longer (1–5 µm than they are wide (~100 nm. Back-scattered electron (BSE images suggest that these nanofibers are platinum-group elements (PGE-bearing and form <5 µm thick layers of bundles which are oriented orthogonal to grains’ surfaces. Trace amounts of Si are most likely associated with PGE-bearing nanofibers. One characteristic fibrous PGM was studied in detail: XRD analyses point to ruthenian hexaferrum. However, the unpolished fibrous PGM shows numerous complex textures on its surface which are suggestive for neoformation processes: (i features suggesting growth of PGE-bearing nanofibers; (ii occurrence of PGM nanoparticles within film material (biofilm? associated with PGE-bearing nanofibers; (iii a Si-rich and crater-like texture hosting PGM nanoparticles and an Ir-rich accumulation of irregular shape; (iv complex PGM nanoparticles with ragged morphologies, resembling sponge spicules and (v oval forms (<1 µm in diameter with included PGM nanoparticles, similar to those observed in experiments with PGE-reducing bacteria. Fibrous PGM found in the limonite may have formed due to supergene (bio-weathering of fibrous Mg-silicates which were incorporated into desulphurized laurite during stages of serpentinization.

  5. Malignant transformation of fibrous dysplasia into chondroblastic osteosarcoma

    Energy Technology Data Exchange (ETDEWEB)

    Kaushik, Shaifali [Department of Radiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA (United States); Department of Radiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA (United States); Smoker, Wendy R.K. [Department of Radiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA (United States); Frable, William J. [Department of Pathology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA (United States)

    2002-02-01

    A case of malignant transformation of polyostotic fibrous dysplasia into maxillary chondroblastic osteosarcoma is presented. The clinical, radiographic, CT, MR imaging features and pathological findings of polyostotic fibrous dysplasia and its malignant transformation are described. Malignant transformation of fibrous dysplasia is rare and has not previously been described in the English literature in this location in McCune-Albright syndrome and in the absence of radiation treatment. (orig.)

  6. Fibrous dysplasia. Clinical review and therapeutic management.

    Science.gov (United States)

    Florez, Helena; Peris, Pilar; Guañabens, Núria

    2016-12-16

    Fibrous dysplasia is a skeletal disorder that is associated with a wide spectrum of clinical manifestations, including localized asymptomatic forms and extensive severe forms with severe bone deformities and endocrinological alterations, depending on age, location, extent and associated processes. Although the treatment of choice is based on bisphosphonates, the therapeutic efficacy of these agents in the control of disease activity remains uncertain. This article reviews the current data available on the treatment of this disease as well as the preliminary data on new therapeutic approaches. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  7. Compressibility of air in fibrous materials

    DEFF Research Database (Denmark)

    Tarnow, Viggo

    1996-01-01

    The dynamic compressibility of air in fibrous materials has been computed for two assumed configurations of fibers which are close to the geometry of real fiber materials. Models with parallel cylinders placed in a regular square lattice and placed randomly are treated. For these models...... the compressibility is computed approximately from the diameter and mean distances between cylinders. This requires calculation of the air temperature, which is calculated for cylinders in a regular lattive by the Wigner-Seitz cell approximation. In the case of random placement, the calculation is done by a summation...

  8. [Solitary naso-sinusal fibrous tumor].

    Science.gov (United States)

    Martínez, V; Jiménez, M L; Cuatrecasas, M; Jürgens, A; de Amesti, C; Orus, C; Fabra, J M

    1995-01-01

    Here we present two clinical cases of solitary naso-sinusal fibrous tumour. This tumour has a mesenchymal origin and has an evident pleural location, with well defined immunohistochemical and ultrastructural characteristics. The clinical manifestation is an apparent benign tumour with an inclination to local aggressiveness. The most effective treatment seems to be surgical removal, but given the low number of cases mentioned (there are only eight cases reported in international literature), and the tendency to eventual recurrence, called for cobalt therapy after surgery. The evolution of clinical cases is irregular.

  9. Angiomatoid fibrous histiocytoma: novel MR imaging findings

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, Salutario J.; Vinson, Emily N. [Duke University Medical Center, Department of Radiology, Durham, NC (United States); Moreno, Courtney Coursey [Emory University School of Medicine, Department of Radiology and Imaging Sciences, Atlanta, GA (United States); Dodd, Leslie G. [University of North Carolina School of Medicine, Department of Pathology and Laboratory Medicine, Chapel Hill, NC (United States); Brigman, Brian E. [Duke University Medical Center, Department of Orthopedic Surgery, Durham, NC (United States)

    2016-05-15

    To describe novel MR imaging features, and clinical characteristics of soft tissue angiomatoid fibrous histiocytoma (AFH) at presentation, local recurrence, and metastases. We described the MRI findings of six cases of histologically proven AFH. Pathologic findings, clinical presentation, and outcome were reviewed. Lesions were primarily cystic. At initial presentation, tumors were surrounded by low signal intensity fibrous pseudocapsule. High signal intensity consistent with the lymphoplasmacytic infiltrate was seen in T2-weighted and post-contrast images as a rim over the hypointense pseudocapsule (double rim sign). High signal intensity infiltrating tumoral cords extended into adjacent tissues, through pseudocapsular defects on T2-weighted and post-contrast images. The cystic component and tumor cell nodularity were demonstrated at post-contrast images. Clinically, lesions were often thought to be benign, underwent marginal resection, developed local recurrence, and one developed second recurrence consisting of metastases. Recurrent tumors appeared as multiple masses, misinterpreted as post-surgical changes. An intramuscular recurrence demonstrated double rim and infiltrating margin. A predominantly well-circumscribed, primarily cystic mass with double-rim and marginal infiltration on MRI suggests the possibility of AFH, in particular in child or young adult. Inclusion of these novel observations in AFH differential diagnosis may have a significant impact on treatment and prevention of recurrence. (orig.)

  10. Self-Organization of Bioinspired Fibrous Surfaces

    Science.gov (United States)

    Kang, Sung Hoon

    Nature uses fibrous surfaces for a wide range of functions such as sensing, adhesion, structural color, and self-cleaning. However, little is known about how fiber properties enable them to self-organize into diverse and complex functional forms. Using polymeric micro/nanofiber arrays with tunable properties as model systems, we demonstrate how the combination of mechanical and surface properties can be harnessed to transform an array of anchored nanofibers into a variety of complex, hierarchically organized dynamic functional surfaces. We show that the delicate balance between fiber elasticity and surface adhesion plays a critical role in determining the shape, chirality, and hierarchy of the assembled structures. We further report a strategy for controlling the long-range order of fiber assemblies by manipulating the shape and movement of the liquid-vapor interface. Our study provides fundamental understanding of the pattern formation by self-organization of bioinspired fibrous surfaces. Moreover, our new strategies offer a foundation for designing a vast assortment of functional surfaces with adhesive, optical, water-repellent, capture and release, and many more capabilities with the structural and dynamic sophistication of their biological counterparts.

  11. Solitary fibrous tumor surrounding the carotid sheath.

    Science.gov (United States)

    Gómez-Oliveira, Guillermo; Alvarez-Flores, Modesto; Arribas-García, Ignacio; Martínez-Gimeno, Carlos

    2010-03-01

    Solitary fibrous tumors (SFTs) are rare spindle cell neoplasms that are mostly found arising from the pleura. Although SFTs recently have been reported in other regions, they are rare in the head and neck and have often been misdiagnosed due to their rarity. SFTs are benign in most cases. Clinically, SFTs usually manifest as well-circumscribed, slow-growing, smooth and painless masses. Symptoms are often minimal, although they may include sore throat, difficulty in swallowing, change of voice or trismus. CT-Scan and MRI are the most sensitive imaging procedures used. The treatment of choice is complete surgical excision of the lesion. Because recurrences have been noted up to 30 years after surgery, long-term follow up is mandatory. In this article, we present a case of a Solitary Fibrous Tumor arising in the parapharyngeal space in a 20-year-old man, involving the carotid sheath, treated by surgical excision with no recurrence after 1 year. The clinical presentation, surgical management and pathological findings are described.

  12. Martian north polar cap summer water cycle

    Science.gov (United States)

    Brown, Adrian J.; Calvin, Wendy M.; Becerra, Patricio; Byrne, Shane

    2016-10-01

    A key outstanding question in Martian science is "are the polar caps gaining or losing mass and what are the implications for past, current and future climate?" To address this question, we use observations from the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) of the north polar cap during late summer for multiple Martian years, to monitor the summertime water cycle in order to place quantitative limits on the amount of water ice deposited and sublimed in late summer. We establish here for the first time the summer cycle of water ice absorption band signatures on the north polar cap. We show that in a key region in the interior of the north polar cap, the absorption band depths grow until Ls = 120, when they begin to shrink, until they are obscured at the end of summer by the north polar hood. This behavior is transferable over the entire north polar cap, where in late summer regions 'flip' from being net sublimating into net condensation mode. This transition or 'mode flip' happens earlier for regions closer to the pole, and later for regions close to the periphery of the cap. The observations and calculations presented herein estimate that on average a water ice layer ∼70 microns thick is deposited during the Ls = 135-164 period. This is far larger than the results of deposition on the south pole during summer, where an average layer 0.6-6 microns deep has been estimated by Brown et al. (2014) Earth Planet. Sci. Lett., 406, 102-109.

  13. Fibrous microcapsules and methods of assembly and use thereof

    Energy Technology Data Exchange (ETDEWEB)

    Stupp, Samuel; Rozkiewicz, Dorota

    2015-01-27

    The present invention relates to assembly of peptide amphiphiles and biopolymers into fibrous microcapsules, and uses thereof. In particular, the present invention provides devices, compositions, and methods for interfacial self-assembly of peptide amphiphiles and biopolyments into fibrous microcapsules, and uses thereof.

  14. Marfan syndrome with multiseptate pneumothorax and mandibular fibrous dysplasia

    Directory of Open Access Journals (Sweden)

    Kate A

    2009-01-01

    Full Text Available We describe a rare case of pneumothorax due to Marfan syndrome associated with fibrous dysplasia of the mandible. Marfan syndrome and fibrous dysplasia were possibly due to a common etiological factor. The association between the two and other tumors described in literature related to Marfan syndrome is discussed.

  15. Recent advances and design considerations in capping systems

    Energy Technology Data Exchange (ETDEWEB)

    DiPippo, G.J.; Monteleone, M.J. [Eckenfelder Inc., Mahwah, NJ (United States)

    1996-12-31

    Capping systems for solid and hazardous waste management facilities and remedial applications have changed significantly over the years. Early designs were virtually monolithic, with little specification of functional properties. The evolution of capping systems has continued and was hastened by the application of geosynthetics and the diligence of those working in the industry in understanding the design considerations for and performance of various capping materials. Capping systems continue to evolve particularly with respect to the application and understanding of the geosynthetic components. Today the design of an effective cap with a total thickness of two feet, or even less as is discussed further below, is possible. Yet much more work remains in various areas such as more precise means of assessing stability, the effects of strain softening, design using seismic considerations, and the like. This paper describes various recent advances in cap design. Three of these advances are covered in some detail; namely, geosynthetic clay layers, subdrainage design using high capacity geonets, and a thin cap section using direct asphalt overlay of geosynthetics for industrial site applications. Several other advances and design considerations are more briefly addressed to illustrate the breadth of the evolution of capping systems.

  16. North Polar Cap

    Science.gov (United States)

    2004-01-01

    [figure removed for brevity, see original site] This week we will be looking at five examples of laminar wind flow on the north polar cap. On Earth, gravity-driven south polar cap winds are termed 'catabatic' winds. Catabatic winds begin over the smooth expanse of the cap interior due to temperature differences between the atmosphere and the surface. Once begun, the winds sweep outward along the surface of the polar cap toward the sea. As the polar surface slopes down toward sealevel, the wind speeds increase. Catabatic wind speeds in the Antartic can reach several hundreds of miles per hour. In the images of the Martian north polar cap we can see these same type of winds. Notice the streamers of dust moving downslope over the darker trough sides, these streamers show the laminar flow regime coming off the cap. Within the trough we see turbulent clouds of dust, kicked up at the trough base as the winds slow down and enter a chaotic flow regime. The horizontal lines in these images are due to framelet overlap and lighting conditions over the bright polar cap. Image information: VIS instrument. Latitude 86.5, Longitude 64.5 East (295.5 West). 40 meter/pixel resolution. Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time. NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen

  17. Electrospun nanocomposite fibrous polymer electrolyte for secondary lithium battery applications

    Science.gov (United States)

    Padmaraj, O.; Rao, B. Nageswara; Jena, Paramananda; Venkateswarlu, M.; Satyanarayana, N.

    2014-04-01

    Hybrid nanocomposite [poly(vinylidene fluoride -co- hexafluoropropylene) (PVdF-co-HFP)/magnesium aluminate (MgAl2O4)] fibrous polymer membranes were prepared by electrospinning method. The prepared pure and nanocomposite fibrous polymer electrolyte membranes were soaked into the liquid electrolyte 1M LiPF6 in EC: DEC (1:1,v/v). XRD and SEM are used to study the structural and morphological studies of nanocomposite electrospun fibrous polymer membranes. The nanocomposite fibrous polymer electrolyte membrane with 5 wt.% of MgAl2O4 exhibits high ionic conductivity of 2.80 × 10-3 S/cm at room temperature. The charge-discharge capacity of Li/LiCoO2 coin cells composed of the newly prepared nanocomposite [(16 wt.%) PVdF-co-HFP+(5 wt.%) MgAl2O4] fibrous polymer electrolyte membrane was also studied and compared with commercial Celgard separator.

  18. Electrochemical Tailoring of Fibrous Polyaniline and Electroless Decoration with Gold and Platinum Nanoparticles.

    Science.gov (United States)

    Abdelhamid, Muhammad E; Snook, Graeme A; O'Mullane, Anthony P

    2016-09-06

    Presented in this work is a facile and quick electrochemical method for controlling the morphology of thick polyaniline (PANi) films, without the use of templates. By stepping the polymerization potential from high voltages to a lower (or series of lower) voltage(s), we successfully controlled the morphology of the polymer, and fibrous structures, unique to each potential step, were achieved. In addition, the resultant film was tested electrochemically for its viability as an electrode material for flexible batteries and supercapacitors. Furthermore, the PANi film was decorated with gold and platinum nanoparticles via an electroless deposition process for possible electrocatalytic applications, whereby the oxidation of hydrazine at the composite was investigated.

  19. A solitary fibrous tumor of the kidney

    Directory of Open Access Journals (Sweden)

    Anuruddha M Abeygunasekera

    2015-01-01

    Full Text Available A solitary fibrous tumor (SFT is an uncommon spindle cell neoplasm that usually occurs in the pleura, but may occur in extrapleural sites. Its occurrence in the kidney is rare. We report a SFT, clinically thought to be a renal cell carcinoma arising in the kidney of a 68-year-old female. The tumor was well-circumscribed and composed of a mixture of spindle cells and dense collagenous bands. Immunohistochemical studies revealed reactivity for CD34, CD99, and Bcl-2 protein, with no staining for keratin or muscle markers, confirming the diagnosis. The immunohistochemical study was the key to diagnosis. Several younger members of her family had colorectal and lung cancers suggesting the possibility of a familial or genetic susceptibility.

  20. Malignant fibrous histiocytoma of the abdominal wall

    Directory of Open Access Journals (Sweden)

    Arif Aslaner

    2015-01-01

    Full Text Available Malignant fibrous histiocytoma (MFH or undifferentiated pleomorphic sarcoma is a type of malignt neoplasm that arises from any soft tissue and bone involving extremities, abdomen and retroperitoneum. MFH of the external oblique abdominis muscle is rare. Surgical resection of the mass is the treatment of choice depending on the stage of the disease and the invasion depth of the tumor. Radiotherapy, chemotherapy and immunotherapy are the other treatment methods. We present a case of a 71-year old man with the diagnosis of MFH on external oblique muscle which was completely resected. We believe that adjuvant chemoradiotherapy following surgical resection of the tumor was the most appropriate treatment for this disease.

  1. Cutaneous changes in fibrous hamartoma of infancy

    Directory of Open Access Journals (Sweden)

    Pilar F-Eire

    2013-01-01

    Full Text Available Only a few published case of fibrous hamartoma of infancy (FHI have commented on the changes in the overlying skin. There are descriptions of individual cases with cutaneous hyperpigmentation, hypertrichosis and hyperhidrosis. It is interesting to describe our case because, to our knowledge, the altered pigmentation of the overlying skin, with hairs on the surface, and eccrine gland hyperplasia combined with abortive hair follicles has not been reported together in association with the FHI. We recommend that all the biopsies must be excisional including overlying skin, thus the epidermal and dermal adnexal changes can be assessed in the microscopic evaluation which could have relevant implications from clinical and embryological point of view.

  2. [Non-ossifying fibroma (metaphyseal fibrous defect)].

    Science.gov (United States)

    Rogozhin, D V; Konovalov, D M; Kozlov, A S; Talalaev, A G; Ektova, A P

    2016-01-01

    Non-ossifying fibroma (NOF) or metaphyseal fibrous defect (MFD) is benign fibroblast proliferation with the presence of osteoclast-like multinucleated giant cells. The most cases of NOF/MFD occur in the metaphysis of the long tubular bones of the lower extremities, more commonly in the metaphysis of the femur and in the proximal metaphysis of the tibia. This lesion has a characteristic X-ray pattern and requires no surgical intervention, except for cases of a pathologic fracture or a risk for the latter. The paper analyzes 35 NOF/MFD cases in children and adolescents. It has been found that one and all patients have undergone surgery, suggesting the low awareness of this abnormality among radiodiagnosticians, pathologists, and surgeons.

  3. Symptomatic fibrous lunato-triquetral coalition

    Energy Technology Data Exchange (ETDEWEB)

    Staebler, A.; Glaser, C.; Reiser, M. [Department of Diagnostic Radiology, Ludwig Maximilians University of Munich (Germany); Resnick, D. [Department of Radiology, Veterans Administration Medical Center, San Diego, CA (United States)

    1999-10-01

    In general, carpal coalitions are considered to be asymptomatic. Incomplete separated joints and associated changes similar to osteoarthritis and pseudoarthrosis are known as possible causes of wrist pain. We present the clinical history, plain-film, and MR imaging findings of two patients with symptomatic fibrous lunato-triquetral coalition. Conventional films disclosed a narrowed space between the lunate and triquetral bone with cysts and sclerosis similar to pseudoarthrosis. Magnetic resonance imaging showed bone marrow edema adjacent to the incomplete separated lunato-triquetral joint and Gd-DTPA enhancing fibrovascular tissue in the synovium and subarticular cysts, explaining the pain over the ulnar-sided wrist. Patients with congenital lunato-triquetral coalition may poorly tolerate stress loading or trauma, resulting in a symptomatic state similar to degenerative arthritis or pseudoarthrosis, which is demonstrated by enhanced MR imaging. (orig.) With 2 figs., 23 refs.

  4. Method of manufacturing fibrous hemostatic bandages

    Science.gov (United States)

    Larsen, Gustavo; Spretz, Ruben; Velarde-Ortiz, Raffet

    2012-09-04

    A method of manufacturing a sturdy and pliable fibrous hemostatic dressing by making fibers that maximally expose surface area per unit weight of active ingredients as a means for aiding in the clot forming process and as a means of minimizing waste of active ingredients. The method uses a rotating object to spin off a liquid biocompatible fiber precursor, which is added at its center. Fibers formed then deposit on a collector located at a distance from the rotating object creating a fiber layer on the collector. An electrical potential difference is maintained between the rotating disk and the collector. Then, a liquid procoagulation species is introduced at the center of the rotating disk such that it spins off the rotating disk and coats the fibers.

  5. A database of worldwide glacier thickness observations

    DEFF Research Database (Denmark)

    Gärtner-Roer, I.; Naegeli, K.; Huss, M.;

    2014-01-01

    One of the grand challenges in glacier research is to assess the total ice volume and its global distribution. Over the past few decades the compilation of a world glacier inventory has been well-advanced both in institutional set-up and in spatial coverage. The inventory is restricted to glacier...... surface observations. However, although thickness has been observed on many glaciers and ice caps around the globe, it has not yet been published in the shape of a readily available database. Here, we present a standardized database of glacier thickness observations compiled by an extensive literature...... review and from airborne data extracted from NASA's Operation IceBridge. This database contains ice thickness observations from roughly 1100 glaciers and ice caps including 550 glacier-wide estimates and 750,000 point observations. A comparison of these observational ice thicknesses with results from...

  6. Schaefer's "family cap".

    Science.gov (United States)

    1994-02-14

    Criticism was directed to Maryland Governor William Donald Shaefer's proposal to put family caps on welfare payments to recipients. The idea was to stop automatic increases in welfare payments if a recipient has an additional child. The objection was that 77%, or the bulk of welfare recipients, have only one or two children, and there is little, if any, evidence that welfare caps influence childbearing. The consequences of such reform would be the penalization of children. The political reality is that symbolism has become more important than facts. Putting a cap on welfare may make people feel better about welfare, and may show fairness to working people who don't get raises when their family size increases, but there are other implications. The messages to welfare recipients to stop having children, but not providing the means to do so, is hypocritical. Medicaid abortions were restricted in 1978 by politicians, but provision for better access to contraceptives was never promoted or achieved. Circumstances limit opportunities. The quality of care in public health clinics is abysmal: long lines and overcrowding, and inadequate proximity to welfare recipients' housing. Transportation, particularly in rural areas, is an impediment to access. It is estimated that only 60% of women eligible for government-funded contraception have access. A sign of serious welfare reform will be budget appropriations for day care, job training, and other reform programs.

  7. What Lies Below a Martian Ice Cap

    Science.gov (United States)

    2008-01-01

    [figure removed for brevity, see original site] Click on image for larger annotated version This image (top) taken by the Shallow Radar instrument on NASA's Mars Reconnaissance Orbiter reveals the layers of ice, sand and dust that make up the north polar ice cap on Mars. It is the most detailed look to date at the insides of this ice cap. The colored map below the radar picture shows the topography of the corresponding Martian terrain (red and white represent higher ground, and green and yellow lower). The radar image reveals four never-before-seen thick layers of ice and dust separated by layers of nearly pure ice. According to scientists, these thick ice-free layers represent approximately one-million-year-long cycles of climate change on Mars caused by variations in the planet's tilted axis and its eccentric orbit around the sun. Adding up the entire stack of ice gives an estimated age for the north polar ice cap of about 4 million years a finding that agrees with previous theoretical estimates. The ice cap is about 2 kilometers (1.2 miles) thick. The radar picture also shows that the boundary between the ice layers and the surface of Mars underneath is relatively flat (bottom white line on the right). This implies that the surface of Mars is not sagging, or bending, under the weight of the ice cap and this, in turn, suggests that the planet's lithosphere, a combination of the crust and the strong parts of the upper mantle, is thicker than previously thought. A thicker lithosphere on Mars means that temperatures increase more gradually with depth toward the interior. Temperatures warm enough for water to be liquid are therefore deeper than previously thought. Likewise, if liquid water does exist in aquifers below the surface of Mars, and if there are any organisms living in that water, they would have to be located deeper in the planet. The topography data are from Mars Orbiter Laser Altimeter, which was flown on NASA's Mars Global Surveyor mission. NPLD stands

  8. Solitary Fibrous Tumor of the Cerebello-Pontine Angle

    Science.gov (United States)

    Biggs, Nigel D.; Fagan, Paul A.; Turner, Jennifer J.; Doust, Bruce

    1999-01-01

    A case is presented of solitary fibrous tumor occurring in the cerebello-pontine angle. There have been only two other reported cases of a solitary fibrous tumors in this region. Imaging studies showed the tumor to be characteristic in shape and position of an acoustic tumor. However, at surgery the tumor was found to have a “rock hard” consistency. Solitary fibrous tumor differs from acoustic schwannoma and meningioma in its histopathological features and in this case, regrowth, after incomplete excision, was extremely rapid. ImagesFigure 2Figure 3Figure 4Figure 5Figure 6 PMID:17171119

  9. Dielectric behavior characterization of functional fibrous-ceramic/polymer nanocomposites

    OpenAIRE

    Dağdeviren, Canan; Dagdeviren, Canan

    2009-01-01

    This study is mainly focused on forming fibrous-ceramic/polymer nanocomposites and characterizing their dielectric behavior. The fibrous-ZnO/PVDF nanocomposite is prepared in two steps. First, a network of nano-scale zinc oxide (ZnO) fibers is produced by sintering electrospun PVA/Zinc Acetate fibers. Second, the ZnO fibrous non-woven mat is sandwiched between two polyvinylidine fluoride (PVDF) thermoplastic polymer films by hot-press casting. Referring to the extensive literature search with...

  10. Fibrous Dysplasia versus Juvenile Ossifying Fibroma: A Dilemma.

    Science.gov (United States)

    Nair, Sreelakshmi N; Kini, Raghavendra; Rao, Prasanna Kumar; Bhandarkar, Gowri P; Kashyp, Roopashri Rajesh; Rai, Manjunath; Naik, Neel; Santhosh, Athul

    2016-01-01

    Fibrous dysplasia (FD) is a condition characterized by excessive proliferation of bone forming mesenchymal cells which can affect one bone (monostotic type) or multiple bones (polyostotic type). It is predominantly noticed in adolescents and young adults. Fibrous dysplasia affecting the jaws is an uncommon condition. The most commonly affected facial bone is the maxilla, with facial asymmetry being the chief complaint. The lesion in many instances is confused with ossifying fibroma (OF). Diagnosis of these two lesions has to be done based on clinical, radiographic, and microscopic findings. Here, we present a case of fibrous dysplasia of maxilla in a nine-year-old boy mimicking juvenile ossifying fibroma.

  11. Fibrous Dysplasia versus Juvenile Ossifying Fibroma: A Dilemma

    Science.gov (United States)

    Rao, Prasanna Kumar; Bhandarkar, Gowri P.; Rai, Manjunath; Naik, Neel; Santhosh, Athul

    2016-01-01

    Fibrous dysplasia (FD) is a condition characterized by excessive proliferation of bone forming mesenchymal cells which can affect one bone (monostotic type) or multiple bones (polyostotic type). It is predominantly noticed in adolescents and young adults. Fibrous dysplasia affecting the jaws is an uncommon condition. The most commonly affected facial bone is the maxilla, with facial asymmetry being the chief complaint. The lesion in many instances is confused with ossifying fibroma (OF). Diagnosis of these two lesions has to be done based on clinical, radiographic, and microscopic findings. Here, we present a case of fibrous dysplasia of maxilla in a nine-year-old boy mimicking juvenile ossifying fibroma. PMID:28101383

  12. Wind blade spar cap and method of making

    Science.gov (United States)

    Mohamed, Mansour H [Raleigh, NC

    2008-05-27

    A wind blade spar cap for strengthening a wind blade including an integral, unitary three-dimensional woven material having a first end and a second end, corresponding to a root end of the blade and a tip end of the blade, wherein the material tapers in width from the first to the second end while maintaining a constant thickness and decreasing weight therebetween, the cap being capable of being affixed to the blade for providing increased strength with controlled variation in weight from the root end to the tip end based upon the tapered width of the material thereof. The present inventions also include the method of making the wind blade spar cap and a wind blade including the wind blade spar cap.

  13. Solitary fibrous tumor of the pleura.

    Science.gov (United States)

    Marak, Creticus P; Dorokhova, Olena; Guddati, Achuta K

    2013-01-01

    Solitary fibrous tumor of the pleura (SFTP) is a rare tumor of mesenchymal origin which can grow to a large size and present with symptoms of cough and pleuritic chest pain. No specific etiological factors for SFTPs are known and they may grow undetected for several years. These tumors are usually benign and may mimic a variety of malignancies. SFTPs are often detected as peripheral opacities on chest X-ray. Unfortunately, fine needle aspiration rarely provides adequate information for a definitive diagnosis. Imaging with computed tomography provides details about the size and extent of any invasion into adjacent tissues. Surgical resection is the mainstay of treatment, and immunohistochemistry of the resected tumor often provides confirmation of the diagnosis. Some SFTPs have been observed to be malignant, and surgical intervention is often lifesaving. There is no adequate data to support the usage of radiotherapy and chemotherapy in the treatment of SFTPs. This tumor exemplifies malignancies which require surgical resection to preempt worse outcomes. Awareness of their presentation and clinical course may help the clinician provide a prompt referral to the thoracic surgeon for resection.

  14. Treating Fibrous Insulation to Reduce Thermal Conductivity

    Science.gov (United States)

    Zinn, Alfred; Tarkanian, Ryan

    2009-01-01

    A chemical treatment reduces the convective and radiative contributions to the effective thermal conductivity of porous fibrous thermal-insulation tile. The net effect of the treatment is to coat the surfaces of fibers with a mixture of transition-metal oxides (TMOs) without filling the pores. The TMO coats reduce the cross-sectional areas available for convection while absorbing and scattering thermal radiation in the pores, thereby rendering the tile largely opaque to thermal radiation. The treatment involves a sol-gel process: A solution containing a mixture of transition-metal-oxide-precursor salts plus a gelling agent (e.g., tetraethylorthosilicate) is partially cured, then, before it visibly gels, is used to impregnate the tile. The solution in the tile is gelled, then dried, and then the tile is fired to convert the precursor salts to the desired mixed TMO phases. The amounts of the various TMOs ultimately incorporated into the tile can be tailored via the concentrations of salts in the solution, and the impregnation depth can be tailored via the viscosity of the solution and/or the volume of the solution relative to that of the tile. The amounts of the TMOs determine the absorption and scattering spectra.

  15. [Malignant fibrous histiocytoma of the penis].

    Science.gov (United States)

    Crisman, G; Margiotta, G; Calabresi, M; Discepoli, S; Leocata, P

    2015-07-01

    According to the most recent World Health Organization (WHO) guidelines a diagnosis of malignant fibrous histiocytoma (MFH) should be made only for lesions composed of tumor cells without evidence of a specific line of differentiation. This is therefore a diagnosis by exclusion which is why the name of undifferentiated high-grade pleomorphic sarcoma (UPS) should be preferred. Soft tissue sarcomas currently have an incidence in all body regions of approximately 20 cases per 1 million inhabitants per year. Soft tissue tumors of the penis represent approximately 5 % of all penile tumors and the incidence of penile sarcomas is estimated to be approximately 0.6-1 case per 100,000 patients. Only seven cases have so far been reported in the literature. This article describes the case of a 61-year-old Caucasian male who presented with a painless mass sited in the upper part of the corpus cavernosa. An incisional biopsy with a subsequent investigation using an extensive immunohistochemical panel were performed and a high-grade undifferentiated pleomorphic sarcoma or pleomorphic storiform MFH was diagnosed. In addition to the case report a literature review is presented to elaborate the discussion on the differential diagnoses of these kinds of lesions.

  16. Intracranial solitary fibrous tumor: Imaging findings

    Energy Technology Data Exchange (ETDEWEB)

    Clarencon, Frederic, E-mail: fredclare5@msn.com [Department of Neuroradiology, Pitie-Salpetriere Hospital, APHP, 75013 Paris (France); Bonneville, Fabrice [Department of Neuroradiology, Hopital Rangueil, Toulouse University Hospital, 31000 Toulouse (France); Rousseau, Audrey [Department of Neuropathology, Pitie-Salpetriere Hospital (France); Galanaud, Damien [Department of Neuroradiology, Pitie-Salpetriere Hospital, APHP, 75013 Paris (France); Kujas, Michele [Department of Neuropathology, Pitie-Salpetriere Hospital (France); Naggara, Olivier [Department of Neuroradiology, St Anne Hospital, 75014 Paris (France); Cornu, Philippe [Department of Neurosurgery, Pitie-Salpetriere Hospital (France); Chiras, Jacques [Department of Neuroradiology, Pitie-Salpetriere Hospital, APHP, 75013 Paris (France)

    2011-11-15

    Objective: To study the neuroimaging features of intracranial solitary fibrous tumors (ISFTs). Materials and methods: Retrospective study of neuroimaging features of 9 consecutive histopathologically proven ISFT cases. Location, size, shape, density, signal intensity and gadolinium uptake were studied at CT and MRI. Data collected from diffusion-weighted imaging (DWI) (3 patients), perfusion imaging and MR spectroscopy (2 patients), and DSA (4 patients) were also analyzed. Results: The tumors most frequently arose from the intracranial meninges (7/9), while the other lesions were intraventricular. Tumor size ranged from 2.5 to 10 cm (mean = 6.6 cm). They presented multilobular shape in 6/9 patients. Most ISFTs were heterogeneous (7/9) with areas of low T2 signal intensity that strongly enhanced after gadolinium administration (6/8). Erosion of the skull was present in about half of the cases (4/9). Components with decreased apparent diffusion coefficient were seen in 2/3 ISFTs on DWI. Spectroscopy revealed elevated peaks of choline and myo-inositol. MR perfusion showed features of hyperperfusion. Conclusion: ISFT should be considered in cases of extra-axial, supratentorial, heterogeneous, hypervascular tumor. Areas of low T2 signal intensity that strongly enhance after gadolinium injection are suggestive of this diagnosis. Restricted diffusion and elevated peak of myo-inositol may be additional valuable features.

  17. Reflective Coating on Fibrous Insulation for Reduced Heat Transfer

    Science.gov (United States)

    Hass, Derek D.; Prasad, B. Durga; Glass, David E.; Wiedemann, Karl E.

    1997-01-01

    Radiative heat transfer through fibrous insulation used in thermal protection systems (TPS) is significant at high temperatures (1200 C). Decreasing the radiative heat transfer through the fibrous insulation can thus have a major impact on the insulating ability of the TPS. Reflective coatings applied directly to the individual fibers in fibrous insulation should decrease the radiative heat transfer leading to an insulation with decreased effective thermal conductivity. Coatings with high infrared reflectance have been developed using sol-gel techniques. Using this technique, uniform coatings can be applied to fibrous insulation without an appreciable increase in insulation weight or density. Scanning electron microscopy, Fourier Transform infrared spectroscopy, and ellipsometry have been performed to evaluate coating performance.

  18. Fabrication of highly modulable fibrous 3D extracellular microenvironments

    KAUST Repository

    Zhang, Xixiang

    2017-06-13

    Three-dimensional (3D) in vitro scaffolds that mimic the irregular fibrous structures of in vivo extracellular matrix (ECM) are critical for many important biological applications. However, structural properties modulation of fibrous 3D scaffolds remains a challenge. Here, we report the first highly modulable 3D fibrous scaffolds self-assembled by high-aspect-ratio (HAR) microfibers. The scaffolds structural properties can be easily tailored to incorporate various physical cues, including geometry, stiffness, heterogeneity and nanotopography. Moreover, the fibrous scaffolds are readily and accurately patterned on desired locations of the substrate. Cell culture exhibits that our scaffolds can elicit strong bidirectional cell-material interactions. Furthermore, a functional disparity between the two-dimensional substrate and our 3D scaffolds is identified by cell spreading and proliferation data. These results prove the potential of the proposed scaffold as a biomimetic extracellular microenvironment for cell study.

  19. General Information about Osteosarcoma and Malignant Fibrous Histiocytoma of Bone

    Science.gov (United States)

    ... to the lung. Bone Metastasis or Bone with Lung Metastasis Osteosarcoma and malignant fibrous histiocytoma may spread to a distant bone and/or the lung. Treatment may include the following: Combination chemotherapy followed ...

  20. Treatment Option Overview (Osteosarcoma and Malignant Fibrous Histiocytoma of Bone)

    Science.gov (United States)

    ... to the lung. Bone Metastasis or Bone with Lung Metastasis Osteosarcoma and malignant fibrous histiocytoma may spread to a distant bone and/or the lung. Treatment may include the following: Combination chemotherapy followed ...

  1. MRI of fibrous cortical defect and non-ossifying fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Mishima, Yoshiko; Aoki, Takatoshi; Watanabe, Hideyuki; Nakata, Hajime; Hashimoto, Hiroshi; Nakamura, Toshitaka [Univ. of Occupational and Environmental Health, Kitakyushu, Fukuoka (Japan). School of Medicine

    1999-02-01

    Fibrous cortical defect and non-ossifying fibroma are the benign fibrous lesions of bone commonly involving children. Their diagnosis is usually done with radiography, and MR examinations are rarely performed. We evaluated MRI findings of 11 lesions in 10 cases of fibrous cortical defect and non-ossifying fibroma. Signal intensity of the lesions was varied and large lesions (2 cm<) tended to show heterogeneous signal intensity on both T1-weighted and T2-weighted images corresponding to a mixture of components including fibrous tissue, hemosiderin and foam cells. MRI helps to delineate the extent of the involved bone and to assess the various histological components of the lesions. However, their diagnosis is basically made on the radiographic findings and the role of MRI is limited. (author)

  2. Ehlers-Danlos syndrome with monostotic fibrous dysplasia

    Directory of Open Access Journals (Sweden)

    Rao A

    1979-01-01

    Full Text Available An unusual case of Ehlers-Danlos syndrome with monostotic fibrous dysplasia of the humorus is presented. The other orthopae-dic manifestations, its complications and associated features are re-viewed and summarised.

  3. Fibrous epulis associated with impacted lower right third molar

    Directory of Open Access Journals (Sweden)

    Ni Putu Mira Sumarta

    2009-12-01

    Full Text Available Background: Epulis or epulides are lesions associated with gingival tissues. Fibrous epulis is a type of hyperplastic fibrous tissue mass located at the gingival which is slow growing, painless, having same color as the oral mucosa and firm on palpation. Anterior regions of the oral cavity are the frequently affected sites as these areas are more prone to be affected by calculus deposition and poor plaque control due to frequent teeth malposition. Removal of any irritating factors and excision of the lesion are the usual treatments. Purpose: This case report presents a rare case of fibrous epulis which occurred in the posterior region of the oral cavity and associated with impacted lower third molar. Case: A case of fibrous epulis at the lower right third molar area of three months duration is presented. The mass was slow growing, painless and on examination it was a pedunculated mass overlying the unerupted lower right third molar, having same color with the oral mucosa and firm on palpation. Clinically, the lesion was diagnosed as fibrous epulis associated with impacted lower right third molar. Case management: The treatment were surgical excision of the epulis and removal of the lower right third molar. The histopathology result showed tissue with squamous epithelial lining, achanthotic fibrous connective tissue, mononuclear inflammatory cells and few capillaries without signs of malignancy. This is consistent with the diagnosis of fibrous epulis. Conclusion: Fibrous epulis, although frequently occurred at the anterior region of the oral cavity, may rarely grow at the area of lower third molar. This phenomenon supports the theory that epulis can grow on any surface of oral mucous membrane as long as local irritants are present.

  4. Effects of compression on the sound absorption of fibrous

    DEFF Research Database (Denmark)

    Castagnede, Bernard; Akninen, Achour; Brouard, Achour

    2000-01-01

    During the compression of a fibrous mat, it is well known that the absorption properties are decreasing. In order to predict this change, some heuristic formulae are proposed which take into account the modifications of the physical parameters(porosity, resistivity, tortousity and shappe factors)......) which enter in the standard "equivalent fluid" model. Numerical predictions are then discussed and compared to experimental data obtained on a fibrous material(uncompressed and the compressed) used in automotive industry....

  5. Polar Cap Retreat

    Science.gov (United States)

    2004-01-01

    13 August 2004 This red wide angle Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a view of the retreating seasonal south polar cap in the most recent spring in late 2003. Bright areas are covered with frost, dark areas are those from which the solid carbon dioxide has sublimed away. The center of this image is located near 76.5oS, 28.2oW. The scene is large; it covers an area about 250 km (155 mi) across. The scene is illuminated by sunlight from the upper left.

  6. Simulation and Analysis of Unbonded Nonwoven Fibrous Structures

    Directory of Open Access Journals (Sweden)

    Behnam Pourdeyhimi

    2006-11-01

    Full Text Available In this work we report on our algorithm for generating 3-D virtual structures resembling un-bonded fibrous webs. The paper discusses short and infinitely long fibers, each emulating a category of nonwoven fibrous medium. The structure Solid Volume Fraction (SVF, being the most important characteristic of a fibrous porous medium, is calculated for different fiberwebs and discussed in details. It is shown that the SVF of the fibrous structures generated by our algorithm is independent of the basis weight. In other words, the porosity of the medium is only a function of the fiber properties – this is as expected. It is also demonstrated that by decreasing the fiber diameter while keeping other properties of the virtual fiberweb constant causes the SVF to decrease almost linearly. The same is not observed for the fiber rigidity. The capability of our algorithm for generating fibrous webs made up of layers of different fibers is demonstrated and their properties are discussed. The application of such virtual fibrous structures in modeling transport phenomena in nonwoven materials and their potential applications in load-deformation studies are discussed.

  7. The usefulness of nucleomedical procedures in diagnosis of fibrous dysplasia

    Energy Technology Data Exchange (ETDEWEB)

    Otsuka, Nobuaki; Fukunaga, Masao; Ono, Shimato (Kawasaki Medical School, Kurashiki, Okayama (Japan)) (and others)

    1989-09-01

    Bone scintigraphy with {sup 99m}Tc-phosphorous compounds and {sup 67}Ga scintigraphy were performed in 8 patients (monostotic 3 cases, polyostotic 5 cases) with fibrous dysplasia. The tendency toward abnormal accumulation of radioactivity on bone scintigraphy was high in the tibia, maxilla, mandibule and ribs. The characteristics of the scintigraphic image at the sites of bone lesion in fibrous dysplasia were judged to be marked (++), moderate (+) or poor or minimal (-), according to the degree of accumulation of radioactivity. Eleven sites of fibrous dysplasia showed marked accumulation and 5 sites showed moderate accumulation. Poor or minimal accumulation was not observed in any fibrous dysplasia lesions. Sclerotic changes on bone roentgenograms appeared as marked accumulation of radionuclides on bone scintigraphy in all cases. Cystic changes on roentgenograms showed a tendency toward moderate accumulation on scintigrams. {sup 67}Ga scans were also all positive for 2 experimental cases (3 sites) of bone lesions of fibrous dysplasia. Thus, bone and {sup 67}Ga scintigraphies appear to be useful and essential in evaluating the pathophysiology of fibrous dysplasia. (author).

  8. Human aortic fibrolipid lesions. Progenitor lesions for fibrous plaques, exhibiting early formation of the cholesterol-rich core.

    Science.gov (United States)

    Bocan, T. M.; Guyton, J. R.

    1985-01-01

    The early development of the lipid-rich core and other features of atherosclerotic fibrous plaques has been elucidated by examining discrete, small regions of raised intima in human aorta, which often bear a resemblance to both fatty streaks and fibrous plaques. Approximately one-fourth of small raised lesions (less than 16 sq mm of surface area) contained little or no stainable lipid, while three-fourths had a characteristic appearance, which included a superficial layer of foam cells, a core of noncrystalline and/or crystalline lipid, and a developed or developing collagenous cap. Total intimal volumes of the lipid-containing lesions, termed "fibrolipid lesions," ranged from 3 to 43 microliters, with the majority less than 16 microliters. Core lipid in the smallest lesions was located in the musculoelastic layer of the intima. In larger lesions the core extended luminally into the elastic hyperplastic layer, and cholesterol crystals were found more frequently. Total cholesterol concentration in fibrolipid lesions was similar to that in fatty streaks; however, the ratio of unesterified to total cholesterol was relatively high, similar to that found in fibrous plaques. It is concluded that 1) the formation of a lipid-rich core and cholesterol crystallization are early events in the development of many raised lesions; 2) the consistent association between the superficial layer of foam cells and the deep-lying lipid-rich core raises the possibility of an influence, possibly indirect, of foam-cell lipid metabolism on core formation; and 3) the fibrolipid lesion may represent one stage in a potential transitional morphologic sequence between fatty streak and fibrous plaque. Images Figure 2 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 PMID:4025509

  9. Control and optimization of Clostridium tyrobutyricum ATCC 25755 adhesion into fibrous matrix in a fibrous bed bioreactor.

    Science.gov (United States)

    Jiang, Ling; Wang, Jufang; Liang, Shizhong; Cai, Jin; Xu, Zhinan

    2011-09-01

    The great performance of a fibrous bed bioreactor (FBB) is mainly dependent on the cell adhesion and immobilization into the fibrous matrix. Therefore, understanding the mechanism and factors controling cell adhesion in the fibrous matrix is necessary to optimize the FBB setup and further improve the fermentability. The adhesion behavior of a strain of Clostridium tyrobutyricum isolated from an FBB was studied, which was proven to be affected by the different environmental conditions, such as growth phase of cells, pH, ionic strength, ionic species, and composition of media. Our results also suggested that electrostatic interactions played an important role on bacteria adhesion into the fibrous matrix. This study demonstrated that the compositions of fermentation broth would have a significant effect on cell adhesion. Consequently, a two-stage glucose supply control strategy was developed to improve the performance of FBB with higher viable cell density in the operation of the FBB setup.

  10. Clinicopathological analysis of solitary fibrous tumor

    Institute of Scientific and Technical Information of China (English)

    Xiumei Zhang; Hai Wang; Shujing Wang; Jinfeng Miao; Zhengai Piao; Yingying Dong

    2012-01-01

    Objective: The aim of this study was to investigate the clinicopathologic characteristics, diagnosis and differential diagnosis, molecular genetics, treatment and prognosis of solitary fibrous tumor (SFT). Methods: The clinicopathological manifestations were analyzed retrospectively in 22 patients with surgically confirmed SFT. Results: There were 12 male patients and 10 female patients, with the age range 33–67 (mean 48.62) years. The SFTs originated from different from parts of the body, including 13 in the chest, 2 in the lungs, 3 in the abdomen, 1 in the lumbosacral area, 2 in the pelvis, and 1 in the left shoulder. There were 19 benign and 3 malignant tumors. Major clinical presentations were local masses and compression symptoms. Microscopy: the tumor was composed of areas of alternating hypercellularity and hypocellularity. The tumor cells were spindle to short-spindle shaped and arranged in fascicular or storiform pattern and hemangiopericytoma-like structure was presented. Immunohistochemically, Vimentin positive rate was 100% (22/22), Bcl-2 positive rate was 95.5% (21/22), CD99 positive rate was 86.4% (19/22), CD34 positive rate was 81.8 (18/22), focally positive for P53, as well as negative CK, S100 and Desmin. Ki67 labelling index was 2%–30%. Conclusion: SFT is a rare tumor which may be found in various parts of human body. SFT mostly is a benign tumor, but a few could be malignant. Its diagnosis mainly rely on its morphologic features and immunohistochemical profiles. The major treatment is to completely resect it by operation and long-term clinical follow-up is necessary.

  11. Gene expression profiling of solitary fibrous tumors.

    Directory of Open Access Journals (Sweden)

    François Bertucci

    Full Text Available BACKGROUND: Solitary fibrous tumors (SFTs are rare spindle-cell tumors. Their cell-of-origin and molecular basis are poorly known. They raise several clinical problems. Differential diagnosis may be difficult, prognosis is poorly apprehended by histoclinical features, and no effective therapy exists for advanced stages. METHODS: We profiled 16 SFT samples using whole-genome DNA microarrays and analyzed their expression profiles with publicly available profiles of 36 additional SFTs and 212 soft tissue sarcomas (STSs. Immunohistochemistry was applied to validate the expression of some discriminating genes. RESULTS: SFTs displayed whole-genome expression profiles more homogeneous and different from STSs, but closer to genetically-simple than genetically-complex STSs. The SFTs/STSs comparison identified a high percentage (∼30% of genes as differentially expressed, most of them without any DNA copy number alteration. One of the genes most overexpressed in SFTs encoded the ALDH1 stem cell marker. Several upregulated genes and associated ontologies were also related to progenitor/stem cells. SFTs also overexpressed genes encoding therapeutic targets such as kinases (EGFR, ERBB2, FGFR1, JAK2, histone deacetylases, or retinoic acid receptors. Their overexpression was found in all SFTs, regardless the anatomical location. Finally, we identified a 31-gene signature associated with the mitotic count, containing many genes related to cell cycle/mitosis, including AURKA. CONCLUSION: We established a robust repertoire of genes differentially expressed in SFTs. Certain overexpressed genes could provide new diagnostic (ALDH1A1, prognostic (AURKA and/or therapeutic targets.

  12. A call to expand regulation to all carcinogenic fibrous minerals

    Science.gov (United States)

    Baumann, F.; Steele, I.; Ambrosi, J.; Carbone, M.

    2013-05-01

    The regulatory term "asbestos" groups only the six fibrous minerals that were commercially used among approximately 400. The carcinogenicity of these six regulated minerals has been largely demonstrated and is related to fiber structure, fiber length/diameter ratio, and bio-persistence. From a public perception, the generic term "asbestos" refers to the fibrous minerals that cause asbestosis, mesothelioma and other cancers. However, other non-regulated fibrous minerals are potentially as dangerous as the regulatory asbestos because they share similar physical and chemical properties, epidemiological studies have demonstrated their relationship with asbestos-related diseases, and both in vitro and in vivo experiments have established the toxicity of these minerals. For example, the non-regulated asbestiform winchite and richterite minerals that contaminated the vermiculite mined from Libby, Montana, (USA) were associated with mesothelioma, lung cancer and asbestosis observed among the area's residents and miners. Many other examples of non-regulated carcinogenic fibrous minerals include, but are not limited to, antigorite, arfvedsonite, balangeroite, carlosturanite, erionite, fluoro-edenite, hornblende, mordenite, palygorskite, and sepiolite. To propose a regulatory definition that would provide protection from all carcinogenic fibers, we have conducted an interdisciplinary literature review to compare the characteristics of "asbestos" and of non-regulated mineral fibers that relate to carcinogenicity. We specifically studied two non-regulated fibrous minerals that are associated with asbestos-related diseases: the serpentine antigorite and the zeolite erionite. Both examples underscore the problem of regulation based on commercial, rather than scientific principles: 1) the occurrence of fibrous antigorite in materials used to pave roads has been correlated with high mesothelioma rates in New Caledonia. Antigorite was also the cause of asbestosis in Poland, and in

  13. Magnetically capped rolled-up nanomembranes.

    Science.gov (United States)

    Streubel, Robert; Thurmer, Dominic J; Makarov, Denys; Kronast, Florian; Kosub, Tobias; Kravchuk, Volodymyr; Sheka, Denis D; Gaididei, Yuri; Schäfer, Rudolf; Schmidt, Oliver G

    2012-08-01

    Modifying the curvature in magnetic nanostructures is a novel and elegant way toward tailoring physical phenomena at the nanoscale, allowing one to overcome limitations apparent in planar counterparts. Here, we address curvature-driven changes of static magnetic properties in cylindrically curved magnetic segments with different radii of curvature. The curved architectures are prepared by capping nonmagnetic micrometer- and nanometer-sized rolled-up membranes with a soft-magnetic 20 nm thick permalloy (Ni(80)Fe(20)) film. A quantitative comparison between the magnetization reversal processes in caps with different diameters is given. The phase diagrams of magnetic equilibrium domain patterns (diameter versus length) are generated. For this, joint experimental, including X-ray magnetic circular dichroism photoelectron emission microscopy (XMCD-PEEM), and theoretical studies are carried out. The anisotropic magnetostatic interaction in cylindrically curved architectures originating from the thickness gradient reduces substantially the magnetostatic interaction between closely packed curved nanowires. This feature is beneficial for racetrack memory devices, since a much higher areal density might be achieved than possible with planar counterparts.

  14. Investigating the effects of capping layer on optical gain of nitride based semiconductor nanostructure lasers

    Science.gov (United States)

    Annabi Milani, E.; Mohadesi, V.; Asgari, A.

    2017-04-01

    In this study, the effects of GaN capping layer on the behaviour of AlGaN/GaN nanostructure based laser is considered. We have employed the self-consistent solution of Poisson and Schrodinger equations for calculation of the energy levels, wave functions and conduction and valance bands profile. The impact of different thicknesses of the capping layer has been studied for sheet carrier density, then on optical gain. The results indicate that, by increasing the thickness of the cap layer, the optical gain decreases.

  15. Effect of non-strained capping layer on excess stress in strained layers

    Institute of Scientific and Technical Information of China (English)

    金智; 杨树人; 马春生; 安海岩; 王本忠; 刘式墉

    1999-01-01

    The effects of the capping-layer thickness and the discrepancy of the numbers of misfit dislocations at the upper and lower interfaces in capped layer on the excess stress are considered. Based on this, the formulae of excess stresses for single- and double-kink models are modified and a new formula is derived, which unifies single- and doublekink models and is valid for arbitrary capping-layer thickness. It is useful to complete the description of the formation and motion of misfit dislocations in strained layers.

  16. Development of Gasless Pyrotechnic Cap

    Science.gov (United States)

    1980-05-01

    beam cathode ray oscillo- scope. The caps were ignited by removing the safety pin . This also triggered the oscilloscope. The change in pressure inside...sensitivity. STRIKER SAFETY PIN PERCUSSION CAP FIXED VOLUME / ;PRESSURE TRANSDUCER TO C.R.O. FIG. 8 - Device used to determine pressure time

  17. Oxidative stress inhibition and oxidant activity by fibrous clays.

    Science.gov (United States)

    Cervini-Silva, Javiera; Nieto-Camacho, Antonio; Gómez-Vidales, Virginia

    2015-09-01

    Fibrous clays (sepiolite, palygorskite) are produced at 1.2m tonnes per year and have a wide range of industrial applications needing to replace long-fibre length asbestos. However, information on the beneficial effects of fibrous clays on health remains scarce. This paper reports on the effect of sepiolite (Vallecas, Spain) and palygorskite (Torrejón El Rubio, Spain) on cell damage via oxidative stress (determined as the progress of lipid peroxidation, LP). The extent of LP was assessed using the Thiobarbituric Acid Reactive Substances assay. The oxidant activity by fibrous clays was quantified using Electron-Paramagnetic Resonance. Sepiolite and palygorskite inhibited LP, whereby corresponding IC50 values were 6557±1024 and 4250±289μgmL(-1). As evidenced by dose-response experiments LP inhibition by palygorskite was surface-controlled. Fibrous clay surfaces did not stabilize HO species, except for suspensions containing 5000μgmL(-1). A strong oxidant (or weak anti-oxidant) activity favours the inhibition of LP by fibrous clays.

  18. Craniofacial fibrous dysplasia - A review of current management techniques

    Directory of Open Access Journals (Sweden)

    Yadavalli Guruprasad

    2012-01-01

    Full Text Available Fibrous dysplasia is a pathologic condition of bone of unknown etiology with no apparent familial, hereditary or congenital basis. Lichtenstein first coined the term in 1938 and in 1942 he and Jaffe separated it from other fibro-osseous lesions. It is a bone tumor that, although benign, has the potential to cause significant cosmetic and functional disturbance, particularly in the craniofacial skeleton. Its management poses significant challenges to the surgeon. Craniofacial fibrous dysplasia is 1 of 3 types of fibrous dysplasia that can affect the bones of the craniofacial complex, including the mandible and maxilla. Fibrous dysplasia is a skeletal developmental disorder of the bone-forming mesenchyme that manifests as a defect in osteoblastic differentiation and maturation. It is a lesion of unknown etiology, uncertain pathogenesis, and diverse histopathology. Fibrous dysplasia represents about 2, 5% of all bone tumors and over 7% of all benign tumours. Over the years, we have gained a better understanding of its etiology, clinical behavior, and both surgical and non-surgical treatments.

  19. Electrospun nanocomposite fibrous polymer electrolyte for secondary lithium battery applications

    Energy Technology Data Exchange (ETDEWEB)

    Padmaraj, O.; Rao, B. Nageswara; Jena, Paramananda; Satyanarayana, N., E-mail: nallanis2011@gmail.com [Department of Physics, Pondicherry University, Pondicherry-605014 (India); Venkateswarlu, M. [R and D, Amaraja batteries, Thirupathi-517501 (India)

    2014-04-24

    Hybrid nanocomposite [poly(vinylidene fluoride -co- hexafluoropropylene) (PVdF-co-HFP)/magnesium aluminate (MgAl{sub 2}O{sub 4})] fibrous polymer membranes were prepared by electrospinning method. The prepared pure and nanocomposite fibrous polymer electrolyte membranes were soaked into the liquid electrolyte 1M LiPF{sub 6} in EC: DEC (1:1,v/v). XRD and SEM are used to study the structural and morphological studies of nanocomposite electrospun fibrous polymer membranes. The nanocomposite fibrous polymer electrolyte membrane with 5 wt.% of MgAl{sub 2}O{sub 4} exhibits high ionic conductivity of 2.80 × 10{sup −3} S/cm at room temperature. The charge-discharge capacity of Li/LiCoO{sub 2} coin cells composed of the newly prepared nanocomposite [(16 wt.%) PVdF-co-HFP+(5 wt.%) MgAl{sub 2}O{sub 4}] fibrous polymer electrolyte membrane was also studied and compared with commercial Celgard separator.

  20. Recurring fibrous dysplasia of anthro maxillary with cranial base invasion

    Directory of Open Access Journals (Sweden)

    Sousa, Kátia Maria Marabuco de

    2009-09-01

    Full Text Available Introduction: Fibrous dysplasia is an osseous lesion with an unknown etiology. It is characterized by the osseous maturation insufficiency. It may affect any bone, but the affection of craniofacial bones is the most critical for otorhinolaryngology. Maxilla is the most affected facial bone and the orbitary invasion is an uncommon event. The symptoms are unspecific and for its low suspicion and uncommonness, the diagnosis is generally late. The monostotic form presents a slow growth and asymptomatic course and needs to be followed up. The polyostotic type has a progressive behavior and is associated to recurrence and complications. Objective: To present two cases of patients with fibrous dysplasia diagnosis and describe the clinical presentation, radiological findings and the treatment of this pathology. Cases Report: Two cases of fibrous dysplasia are reported, which initially presented unspecific symptomatology, but with characteristic radiologic signs. They were submitted to surgical treatment for resection of the lesions and evolved with frequent recurrences with extensive affection of the facial sinuses, one patient had cranial base invasion and frontal craniotomy was needed for tumoral excision. Final Comments: Fibrous dysplasia is an uncommon osteopathy. The tomography is the choice method for characterization of the tumoral expansion, and helps in the surgical planning. The surgical strategy is indicated for symptomatic lesions, functions alterations or anatomic disorders. This article describes two uncommon manifestations of recurrent fibrous dysplasia with an extensive affection of anthro maxillary, ethmoidal and sphenoid sinuses, in addition to orbitary and cranial base invasion.

  1. [About a case of calcifying fibrous tumor of the pleura].

    Science.gov (United States)

    Rocas, Delphine; Thivolet-Béjui, Françoise; Tronc, François; Chalabreysse, Lara

    2015-12-01

    Calcifying fibrous tumor is a rare soft tissue benign tumor (OMS 2002). Some pleural localisations are described, which affect slightly older individuals than the other soft tissue forms. The calcifying fibrous tumor is included in the 2004 World Health Organization classification of pleural tumors. A pleural tumor located in the right inferior pulmonary lobe is diagnosed in a 59-year-old man. This pleural tumor is macroscopically well-circumscribed. Histologically, the rare spindle tumoral cells are located between bundles of a collagenous tissue, sometimes hyalinized, with psammomatous or dystrophic calcifications. The tumoral cells have a fibrohistiocytic origin. They stain positively for antibodies against vimentin, factor XIIIa, CD68, CD163, CD34. Antibodies against smooth muscle actin, desmin, PS100, ALK1 and EBV are negative. Main differencial diagnoses are other benign pleural tumors (solitary fibrous tumor, inflammatory myofibroblastique tumor), some malignant tumors (desmoplastic malignant pleural mesothelioma) and pleural pseudotumors (calcified pleural plaques, chronic fibrous pleuritis, amylose, hyalinizing granuloma). Our case is the 15th pleural calcifying fibrous tumor being reported. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  2. Computed tomographic features of fibrous dysplasia of maxillofacial region

    Energy Technology Data Exchange (ETDEWEB)

    Sontakke, Subodh Arun; Karjodka, Freny R [Nair Hospital Dental College, Mumba (India); Umarji, Hemant R [Government Dental College and Hospital, Mumbai (India)

    2011-03-15

    This study was to find the computed tomographic features of fibrous dysplasia of the maxillofacial region. All eight cases included in the study reported either to Government Dental College and Hospital or Nair Hospital Dental College, Mumbai between 2003 and 2009. The patients were prescribed computed tomogram in addition to conventional radiographs of maxillofacial region which were studied for characteristic features of fibrous dysplasia. The diagnosis of fibrous dysplasia was confirmed by histopathological report. All cases showed the ill-defined margins of lesions except in the region where the lesions were extending to cortex of the involved bone. Internal structure of all cases showed ground glass appearance. Four cases of maxillary lesion showed the displacement of maxillary sinus maintaining the shape of maxillary sinus. Two cases showed complete obliteration of maxillary sinus. Displacement of inferior alveolar canal did not follow any typical pattern in any of the cases but was displaced in different directions. The craniofacial type of fibrous dysplasia is as common as fibrous dysplasia of jaw. The margins, extent, internal structure and effect on surrounding structure are well detected on computed tomographic images.

  3. Radiological analysis of polyostotic fibrous dysplasia in skeletal system

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Ma Rie; Kim, Jin Sik; Kim, Han Suk [National Medical Center, Seoul (Korea, Republic of); Park, Soo Soung [Chung Ang University College of Medicine, Seoul (Korea, Republic of)

    1984-12-15

    Over a period of recent 3 years, the 5 cases of polyostotic fibrous dysplasia were proven histologically at National Medical Center, and they were evaluated and analyzed radiologically and clinically. The results were as follows: 1. The age of 5 patients ranged from 12 to 21. 2. In general, clinical symptoms of these patients were pain of affected sites and swelling , fracture, walking disturbance of lower extremities. 3. The order of frequent site of polyostotic fibrous dysplasia was skull (4 cases), femur (3 cases), maxilla (2 case), humerus, tibia, rib, radius, metacarpal bone and phalanx. 4. The characteristic radiological findings of polyostotic fibrous dysplasia were multicystic lesions with ground glass appearance, osteosclerosis, cortical thinning and pathologic fracture and deformity of long bones. Particularly, in the extremities, multicystic radiolucencies, groud glass appearance, shepherd's crook and coxa vara deformities were noticed, and in the skull and maxilla, sclerotic changes were principally demonstrated.

  4. Polyostotic Fibrous Dysplasia of Cranio-Maxillofacial Area

    Energy Technology Data Exchange (ETDEWEB)

    Han, Jin Woo; Kwon, Hyuk Rok; Lee, Jin Ho; Park, In Woo [Dept. of Oral and Maxillofacial Radiology, College of Dentistry, Kangnung National University, Kangnung (Korea, Republic of)

    2000-06-15

    Fibrous dysplasia is believed to be a hamartomatous developmental lesion of unknown origin. This disease is divided into monostotic and polyostotic fibrous dysplasia. Polyostotic type can be divided into craniofacial type, Lichtenstein-Jaffe type, and McCune-Albright syndrome. In this case, a 31-year-old female presented spontaneous loss of right mandibular teeth before 5 years and has shown continuous expansion of right mandibular alveolus. Through the radiographic view, the coarse pattern of the mixed radiopaque-lucent lesion was seen on the right mandibular body, and there was diffuse pattern of the mixed radiopaque-lucent lesion with ill-defined margin in the left mandibular body. In the right calvarium, the lesion had cotton-wool appearance. Partial excision for contouring, multiple extraction, and alveoloplasty were accomplished under general anesthesia for supportive treatment. Finally we could conclude this case was polyostotic fibrous dysplasia of cranio-maxillofacial area based on the clinical, radiologic finding, and histopathologic examination.

  5. 4D fibrous materials: characterising the deployment of paper architectures

    Science.gov (United States)

    Mulakkal, Manu C.; Seddon, Annela M.; Whittell, George; Manners, Ian; Trask, Richard S.

    2016-09-01

    Deployment of folded paper architecture using a fluid medium as the morphing stimulus presents a simple and inexpensive methodology capable of self-actuation; where the underlying principles can be translated to develop smart fibrous materials capable of programmable actuations. In this study we characterise different paper architectures and their stimuli mechanisms for folded deployment; including the influence of porosity, moisture, surfactant concentration, temperature, and hornification. We observe that actuation time decreases with paper grammage; through the addition of surfactants, and when the temperature is increased at the fluid-vapour interface. There is a clear effect of hydration, water transport and the interaction of hydrogen bonds within the fibrous architecture which drives the deployment of the folded regions. The importance of fibre volume fraction and functional fillers in shape recovery was also observed, as well as the effect of a multilayer composite paper system. The design guidelines shown here will inform the development of synthetic fibrous actuators for repeated deployment.

  6. Malign Fibrous Histiocytoma of the Bladder: A Rare Case Report

    Directory of Open Access Journals (Sweden)

    Ižbrahim Bozkurt

    2014-06-01

    Full Text Available Malignant fibrous histocytoma is a mesenchimal tumor, which was described in 1964. It is the most common soft tissue sarcoma in patients over the age of 40 years. There were very few reports about malignant fibrous histocytoma in urinary tract especially in bladder with 30 patients. Patients usually present with gross hematuria. Because of its agressive characteristics; recurrences, progressions and metastasis are likely. Tumor grade, tumor size, amount of invasion and histological type are the risk factors for metastasis. Early radical cystectomy is the first treatment option because of poor prognosis of these tumors but usually can not be sufficient. Chemotherapy and radiotherapy are used to as an alternative treatment or adjuvant treatment with surgery. We would like to present a bladder malignant fibrous histocytoma case to contribute to the lirature.

  7. Inverse Problem of Air Filtration of Nanoparticles: Optimal Quality Factors of Fibrous Filters

    Directory of Open Access Journals (Sweden)

    Dahua Shou

    2015-01-01

    Full Text Available Application of nanofibers has become an emerging approach to enhance filtration efficiency, but questions arise about the decrease in Quality factor (QF for certain particles due to the rapidly increasing pressure drop. In this paper, we theoretically investigate the QF of dual-layer filters for filtration of monodisperse and polydisperse nanoparticles. The inverse problem of air filtration, as defined in this work, consists in determining the optimal construction of the two-layer fibrous filter with the maximum QF. In comparison to a single-layer substrate, improved QF values for dual-layer filters are found when a second layer with proper structural parameters is added. The influences of solidity, fiber diameter, filter thickness, face velocity, and particle size on the optimization of QF are studied. The maximum QF values for realistic polydisperse particles with a lognormal size distribution are also found. Furthermore, we propose a modified QF (MQF accounting for the effects of energy cost and flow velocity, which are significant in certain operations. The optimal MQF of the dual-layer filter is found to be over twice that of the first layer. This work provides a quick tool for designing and optimizing fibrous structures with better performance for the air filtration of specific nanoparticles.

  8. Direct E-jet printing of three-dimensional fibrous scaffold for tendon tissue engineering.

    Science.gov (United States)

    Wu, Yang; Wang, Zuyong; Ying Hsi Fuh, Jerry; San Wong, Yoke; Wang, Wilson; San Thian, Eng

    2017-04-01

    Tissue engineering (TE) offers a promising strategy to restore diseased tendon tissue. However, a suitable scaffold for tendon TE has not been achieved with current fabrication techniques. Herein, we report the development of a novel electrohydrodynamic jet printing (E-jetting) for engineering 3D tendon scaffold with high porosity and orientated micrometer-size fibers. The E-jetted scaffold comprised tubular multilayered micrometer-size fibrous bundles, with interconnected spacing and geometric anisotropy along the longitudinal direction of the scaffold. Fiber diameter, stacking pattern, and interfiber distance have been observed to affect the structural stability of the scaffold, of which the enhanced mechanical strength can be obtained for scaffolds with thick fibers as the supporting layer. Human tenocytes showed a significant increase in cellular metabolism on the E-jetted scaffolds as compared to that on conventional electrospun scaffolds (2.7-, 2.8-, and 3.1-fold increase for 150, 300, and 600 µm interfiber distance, respectively; p scaffolds provided structural support for human tenocytes to align with controlled orientation along the longitudinal direction of the scaffold, and promoted the expression of collagen type I. For the first time, E-jetting has been explored as a novel scaffolding approach for tendon TE, and offers a 3D fibrous scaffold to promote organized tissue reconstruction for potential tendon healing. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 616-627, 2017.

  9. Optimization of sound absorbing performance for gradient multi-layer-assembled sintered fibrous absorbers

    Science.gov (United States)

    Zhang, Bo; Zhang, Weiyong; Zhu, Jian

    2012-04-01

    The transfer matrix method, based on plane wave theory, of multi-layer equivalent fluid is employed to evaluate the sound absorbing properties of two-layer-assembled and three-layer-assembled sintered fibrous sheets (generally regarded as a kind of compound absorber or structures). Two objective functions which are more suitable for the optimization of sound absorption properties of multi-layer absorbers within the wider frequency ranges are developed and the optimized results of using two objective functions are also compared with each other. It is found that using the two objective functions, especially the second one, may be more helpful to exert the sound absorbing properties of absorbers at lower frequencies to the best of their abilities. Then the calculation and optimization of sound absorption properties of multi-layer-assembled structures are performed by developing a simulated annealing genetic arithmetic program and using above-mentioned objective functions. Finally, based on the optimization in this work the thoughts of the gradient design over the acoustic parameters- the porosity, the tortuosity, the viscous and thermal characteristic lengths and the thickness of each samples- of porous metals are put forth and thereby some useful design criteria upon the acoustic parameters of each layer of porous fibrous metals are given while applying the multi-layer-assembled compound absorbers in noise control engineering.

  10. Burner cap assembly

    Energy Technology Data Exchange (ETDEWEB)

    Craver, A.F.

    1974-05-07

    A new gas burner for domestic gas ranges is economical in cost, has the proper configuration for the aesthetics of the housewife, and overcomes certain undesirable operational features of conventional gas burners. The design eliminates the burner base, eliminates the venturi section of the mixing tube, incorporates a new cap with a novel port configuration, and, in the preferred version, eliminates the air shutter at the primary air inlet to the mixing tube. Because the voluminous conventional burner base has been eliminated, the amount of unburned gas escaping after turning the burner off is no longer sizable enough to disturb the cook. The burner produces less carbon monoxide but a higher temperature and greater efficiency than conventional burners and may be placed much closer to the utensil. Thus, no expensive supplemental mounting brackets are needed below the bottom of the burner box; the burner may even be mounted directly on the oven top without danger of oven contraction/expansion moving the unit out of the allowable burner-height range. The unit requires less cleaning and is less susceptible to closure by lint, dirt, and grease.

  11. Malignant fibrous histiocytoma of colon: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae Hwan; Jee, Keum Nahn [Dankook University College of Medicine, Cheonan (Korea, Republic of)

    2006-03-15

    Gastrointestinal malignant fibrous histiocytomas (MFH) are very rare and only about 30 cases have been reported in the English literature, among which 20 cases were from colorectal MFHs. A small bowel MFH with intussusception has been the only reported case in the Korean medical literature. A 52-year-old male presented with complaints of recently developed and aggravated right upper abdominal pain. We present the CT appearance and the clinico-pathologic findings of his primary inflammatory malignant fibrous histiocytoma, which arose from the subserosal layer of the ascending colon with tumor infiltration in all the layers. The colon showed extensive hemorrhagic necrosis and repetitive multifocal microperforations with resultant panperitonitis.

  12. Focal electroencephalography rhythm asymmetry due to focal skull fibrous dysplasia

    Directory of Open Access Journals (Sweden)

    Michael A. Meyer

    2014-06-01

    Full Text Available An unusual pervasive and persistent asymmetry in background rhythm was found on surface electroencephalography (EEG recordings in a 22 year old with new onset of generalized seizure activity. Radiographic correlation with computed tomography, positron emission tomography and bone scan imaging uncovered that the higher amplitude left frontal-parietal background activity was related to a circumscribed area of left frontal-parietal fibrous dysplasia affecting the skull. This case report emphasizes that the presumed higher electrical conductance of fibrous dysplasia lead to a greater transparency of normal background rhythms, and must be taken into account as a form of breach rhythm for accurate EEG interpretation.

  13. Fibrous dysplasia localized to spine: a diagnostic dilemma

    Energy Technology Data Exchange (ETDEWEB)

    Gogia, Nidhi; Gulati, Manpreet [All India Institute of Medical Sciences, Department of Radiology, New Delhi (India); Marwaha, V. [All India Institute of Medical Sciences, Department of Radiology, New Delhi (India); All India Institute of Medical Sciences, Department of Medicine, New Delhi (India); Atri, S. [All India Institute of Medical Sciences, Department of Pathology, New Delhi (India); Gupta, Rajiva [All India Institute of Medical Sciences Ansari Nagar, Department of Medicine, Division of Rheumatology and Clinical Immunology, New Delhi (India)

    2007-06-15

    Fibrous dysplasia of the spine is uncommon, especially in monostotic form. Isolated vertebral involvement in polyostotic form is very rare. We report a case of polyostotic fibrous dysplasia with lesions localized to dorso-lumbar spine in a 45-year-old rheumatoid arthritis patient. No associated appendicular lesions, cutaneous manifestations or endocrinopathies were seen. The extreme rarity of this type of lesion can pose a diagnostic dilemma, and biopsy is required for diagnosis. The association with rheumatoid arthritis in our case seems to be a chance occurrence. (orig.)

  14. Non-steady-state aerosol filtration in nanostructured fibrous media.

    Science.gov (United States)

    Przekop, Rafal; Gradoń, Leon

    2011-06-28

    The filtration of aerosol particles using composites of nano- and microsized fibrous structures is a promising method for the effective separation of nanoparticles from gases. A multi-scale physical system describing the flow pattern and particle deposition at a non-steady-state condition requires an advanced method of modelling. The combination of lattice Boltzmann and Brownian dynamics was used for analysis of the particle deposition pattern in a fibrous system. The dendritic structures of deposits for neutral and charged fibres and particles are present. The efficiency of deposition, deposit morphology, porosity and fractal dimension were calculated for a selected operational condition of the process.

  15. Electrocrystallization of fibrous silver deposits from nitrate melts: Experiments and modeling

    Directory of Open Access Journals (Sweden)

    Murashova I.B.

    2003-01-01

    Full Text Available Fibrous silver deposits have been obtained in molten nitrates on a moving cathode. Cylindrical silver cathode was lifted from the melt AgNO3-NaNO3-KNO3. It is found that the dimensions of the silver threads as well as their shape and thickness depend on the electrolysis parameters: the values of current and velocity of the cathode lifting. Systematic study of the silver dendrite structure has been performed on a scanning electron microscope. Geometric characteristics have been evaluated statistically and regression equations linking these constitutive properties of the deposits with the values of current and of lifting velocity have been obtained. A criterion for the description of dendrite shape under different conditions is proposed.

  16. ATLAS - End-Cap calorimeter

    CERN Multimedia

    2006-01-01

    The End-cap calorimeter was moved with the help of the rails and this calorimeter will measure the energy of particles close to the beam axis when protons collide. Cooling is important for maximum detector efficiency.

  17. ATLAS - End-Cap calorimeter

    CERN Multimedia

    2006-01-01

    The End-cap calorimeter was moved with the help of the rails and this calorimeter will measure the energy of particles close to the beam axis when protons collide. Cooling is important for maximum detector efficiency.

  18. Acoustic Monitoring of the Arctic Ice Cap

    Science.gov (United States)

    Porter, D. L.; Goemmer, S. A.; Chayes, D. N.

    2012-12-01

    Introduction The monitoring of the Arctic Ice Cap is important economically, tactically, and strategically. In the scenario of ice cap retreat, new paths of commerce open, e.g. waterways from Northern Europe to the Far East. Where ship-going commerce is conducted, the U.S. Navy and U.S. Coast Guard have always stood guard and been prepared to assist from acts of nature and of man. It is imperative that in addition to measuring the ice from satellites, e.g. Icesat, that we have an ability to measure the ice extent, its thickness, and roughness. These parameters play an important part in the modeling of the ice and the processes that control its growth or shrinking and its thickness. The proposed system consists of three subsystems. The first subsystem is an acoustic source, the second is an array of geophones and the third is a system to supply energy and transmit the results back to the analysis laboratory. The subsystems are described below. We conclude with a plan on how to tackle this project and the payoff to the ice cap modeler and hence the users, i.e. commerce and defense. System Two historically tested methods to generate a large amplitude multi-frequency sound source include explosives and air guns. A new method developed and tested by the University of Texas, ARL is a combustive Sound Source [Wilson, et al., 1995]. The combustive sound source is a submerged combustion chamber that is filled with the byproducts of the electrolysis of sea water, i.e. Hydrogen and Oxygen, an explosive mixture which is ignited via a spark. Thus, no additional compressors, gases, or explosives need to be transported to the Arctic to generate an acoustic pulse capable of the sediment and the ice. The second subsystem would be geophones capable of listening in the O(10 Hz) range and transmitting that data back to the laboratory. Thus two single arrays of geophones arranged orthogonal to each other with a range of 1000's of kilometers and a combustive sound source where the two

  19. Fibrous dysplasia of the jaws associated with secondary hyperparathyroidism: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Whi, Jung Hyun; Kim, Young Joo; Chun, Kyung Ah; Kim, Ki Tae; Chang, Eun Deok; Kim, Young Ok; Lee, Won [The Catholic University of Korea, Uijongbu (Korea, Republic of)

    2007-06-15

    There have been few reports on fibrous dyplasia associated with secondary hyperparathyroidism. We report a case of a hemodialysis patient with secondary hyperparathyroidism concomitant with fibrous dysplasia of the jaws causing an abnormal deformity.

  20. Filtration efficiency of an electrostatic fibrous filter: Studying filtration dependency on ultrafine particle exposure and composition

    DEFF Research Database (Denmark)

    Ardkapan, Siamak Rahimi; Johnson, Matthew S.; Yazdi, Sadegh

    2014-01-01

    The objective of the present study is to investigate the relationship between ultrafine particle concentrations and removal efficiencies for an electrostatic fibrous filter in a laboratory environment. Electrostatic fibrous filters capture particles efficiently, with a low pressure drop. Therefor...

  1. Malignant fibrous histiocytoma of the colon. Report of the case and review of the subject.

    Science.gov (United States)

    Baltaziak, M; Zimnoch, L; Sobaniec-Lotowska, M; Kemona, A; Dziecioł, J

    1993-01-01

    Primary and metastatic malignant fibrous histiocytoma of the alimentary tract is uncommon, even though it is the most frequently diagnosed malignant soft tissue tumor in adults. In this report, we describe a case of malignant fibrous histiocytoma of the colon.

  2. Localized fibrous tumor of the liver: imaging findings

    Energy Technology Data Exchange (ETDEWEB)

    Lecesne, R.; Drouillard, J.; Laurent, F. [Service d`Imagerie Medicale-Radiologie Diagnostique et Therapeutique, Hopital du Haut-Leveque, CHU Bordeaux, Pessac (France); Le Bail, B. [Department d`Anatomie et Cytologie Pathologiques, Groupe Hospitalier Pellegrin, CHU Bordeaux, Place Amelie Raba-Leon, Bordeaux (France); Saric, J. [Service de Chirurgie Digestive, Groupe Saint-Andre, CHU Bordeaux (France); Balabaud, C. [Service des Maladies de L`Appareil Digestif, Groupe Saint-Andre, CHU Bordeaux (France)

    1998-02-01

    We report the imaging of a localized fibrous tumor of the liver, focusing on color Doppler US, CT, MR imaging, and angiographic findings. We discuss the differential diagnosis of such a rare, benign lesion of the liver. Detailed imaging of this tumor has not been reported in the literature previously. (orig.) With 6 figs., 10 refs.

  3. Use of Zoledronic Acid in Paediatric Craniofacial Fibrous Dysplasia

    Directory of Open Access Journals (Sweden)

    Chiara Di Pede

    2016-01-01

    Full Text Available We describe a case of a paediatric patient affected by mandibular fibrous dysplasia (FD with severe and chronic pain who was successfully treated with zoledronic acid (ZOL: a third-generation bisphosphonate. Further research is needed to assess its safety and efficacy as a treatment option for FD in the paediatric population.

  4. Electrospinning of caseinates to create protective fibrous mats

    Science.gov (United States)

    Electrospinning is a nonthermal process that produces fibers on the micron- or nano-scale from a polymer solution. If produced by electrospinning of biopolymer solutions, fibrous mats may be created for protecting foods and allowing for the preservation and controlled release of bioactives for healt...

  5. Imitation model of destruction of aviation fibrous polymeric composite materials

    Directory of Open Access Journals (Sweden)

    В. М. Синеглазов

    2000-12-01

    Full Text Available Considered are models imitating influence of lighting on dielectric construction materials with elements of lighting protection. Described are models of current spreading in multilayer materials and thermal destruction of fibrous polymeric composite materials caused by lighting current flowing on such materials

  6. Transarterial Onyx Embolization of an Orbital Solitary Fibrous Tumor

    Science.gov (United States)

    Hashemi, Nafiseh; Ling, Jeanie D.; Soparkar, Charles; Sami, Mirwat; Ellezam, Benjamin; Klucznik, Richard; Lee, Andrew G.; Chévez-Barrios, Patricia

    2015-01-01

    Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm sometimes found in the orbit. We report a case of an aggressive orbital SFT with enlarged feeding vessels that was successfully resected immediately after transarterial embolization with Onyx (ethylene vinyl alcohol copolymer). To our knowledge, this is the first report showing the histopathology of Onyx embolization material in an orbital SFT. PMID:27171911

  7. Compressibility of CNT-Grafted Fibrous Reinforcements: A Theory

    NARCIS (Netherlands)

    Lomov, S.V.; Koissin, V.; Karahan, M.; Godara, A.; Gorbatikh, L.; Verpoest, I.

    2010-01-01

    The paper introduces a theoretical model of compressibility of a nanotube forest with randomly oriented nanotubes, which is applied to predict compressibility of a fibrous reinforcement with CNT-grafted fibres. It is shown that the pressure needed to achieve the target fibre volume fraction of the p

  8. [Poliostotic fibrous dysplasia with affectation of cervical rachis].

    Science.gov (United States)

    Lumbreras, Ruth; Aznar, Jose María; Castro, Angel; Modrego, Francisco Javier; Ballester, Juan José; Espallargas, Teresa

    2007-01-01

    The fibrous dysplasia is a benign although progressive dysfunction, in which a gene mutation originates the production of fibrous disorganized bony matrix. The bony tissue is replaced by bony tissue in expansion (amorph conjuntival tissue) that produces bony deformities in some patients, pain, pathological fractures or deambulation disorders. The diagnosis is important since ocasionally the first symptom is the fracture. We show up the case of a 21 year-old patient with pain clinic in high cervical region. The complementary tests (radiology, bone scintigrraphy and MRI) and anatomo-pathology confirmed the diagnosis of polyostotic fibrous dysplasia with cranial (occipital, esfenoides and right frontal and temporal bone), iliac, femoral, tibial and cervical (apophysis of C2) affectation. Our attitude was of carrying out a narrow observation by means of periodical strict controls, advising to avoid hard activities or contact sports. To the five years the patient is free of symptomatology. Radiologically the injuries have been stabilized. The fibrous dysplasia can affect to a single bone (monostotic) or to several (polyostotic). In occasions it is associated to endocrine dysfunctions and skin pigmentations in McCune-Albright's syndrome. We confront a pathology that specifies an anatomo-pathologic diagnosis to be confirmed, an extension diagnosis to detect asymptomatic focuses and whose treatment is symptomatic in most of the cases only using surgery in frank deformities or when the fracture risk is considerable, although the recurrence is frequent. The malignization is exceptional but possible that's why continuous observation is needed. The radiation therapy is radically contraindicated.

  9. Solitary fibrous tumor of the thyroid with capsular invasion.

    Science.gov (United States)

    Bohórquez, Concepción Lara; González-Cámpora, Ricardo; Loscertales, Miguel Congregado; Escudero, Antonio García; Mezquita, Jesús Congregado

    2003-01-01

    This report describes the clinical and pathologic findings of a peculiar case of solitary fibrous tumor of the thyroid gland that showed capsular invasion. After four and a half years of follow-up, neither local recurrence nor metastasis has developed.

  10. Compressibility of CNT-Grafted Fibrous Reinforcements: A Theory

    NARCIS (Netherlands)

    Lomov, S.V.; Koysin, V.; Karahan, M.; Godara, A.; Gorbatikh, L.; Verpoest, I.

    2010-01-01

    The paper introduces a theoretical model of compressibility of a nanotube forest with randomly oriented nanotubes, which is applied to predict compressibility of a fibrous reinforcement with CNT-grafted fibres. It is shown that the pressure needed to achieve the target fibre volume fraction of the

  11. Direct Numerical Simulation of Liquid Transport Through Fibrous Porous Media

    Science.gov (United States)

    Palakurthi, Nikhil Kumar

    Fluid flow through fibrous media occurs in many industrial processes, including, but not limited, to fuel cell technology, drug delivery patches, sanitary products, textile reinforcement, filtration, heat exchangers, and performance fabrics. Understanding the physical processes involved in fluid flow through fibrous media is essential for their characterization as well as for the optimization and development of new products. Macroscopic porous-media equations require constitutive relations, which account for the physical processes occurring at the micro-scale, to predict liquid transport at the macro-scale. In this study, micro-scale simulations were conducted using conventional computational fluid dynamics (CFD) technique (finite-volume method) to determine the macroscopic constitutive relations. The first part of this thesis deals with the single-phase flow in fibrous media, following which multi-phase flow through fibrous media was studied. Darcy permeability is an important parameter that characterizes creeping flow through a fibrous porous medium. It has a complex dependence on the medium's properties such as fibers' in-plane and through-plane orientation, diameter, aspect ratio, curvature, and porosity. A suite of 3D virtual fibrous structures with a wide range of geometric properties were constructed, and the permeability values of the structures were calculated by solving the 3D incompressible Navier-Stokes equations. The through-plane permeability was found to be a function of only the fiber diameter, the fibers' through-plane orientation, and the porosity of the medium. The numerical results were used to extend a permeability-porosity relation, developed in literature for 3D isotropic fibrous media, to a wide range of fibers' through-plane orientations. In applications where rate of capillary penetration is important, characterization of porous media usually involves determination of either the effective pore radius from capillary penetration experiments

  12. Comparison of human CAP and CAP2, homologs of the yeast adenylyl cyclase-associated proteins.

    Science.gov (United States)

    Yu, G; Swiston, J; Young, D

    1994-06-01

    We previously reported the identification of human CAP, a protein that is related to the Saccharomyces cerevisiae and Schizosaccharomyces pombe adenylyl cyclase-associated CAP proteins. The two yeast CAP proteins have similar functions: the N-terminal domains are required for the normal function of adenylyl cyclase, while loss of the C-terminal domains result in morphological and nutritional defects that are unrelated to the cAMP pathways. We have amplified and cloned cDNAs from a human glioblastoma library that encode a second CAP-related protein, CAP2. The human CAP and CAP2 proteins are 64% identical. Expression of either human CAP or CAP2 in S. cerevisiae cap- strains suppresses phenotypes associated with deletion of the C-terminal domain of CAP, but does not restore hyper-activation of adenylyl cyclase by RAS2val19. Similarly, expression of either human CAP or CAP2 in S. pombe cap- strains suppresses the morphological and temperature-sensitive phenotypes associated with deletion of the C-terminal domain of CAP in this yeast. In addition, expression of human CAP, but not CAP2, suppresses the propensity to sporulate due to deletion of the N-terminal domain of CAP in S. pombe. This latter observation suggests that human CAP restores normal adenylyl cyclase activity in S. pombe cap- cells. Thus, functional properties of both N-terminal and C-terminal domains are conserved between the human and S. pombe CAP proteins.

  13. Restrictive lung disease and cor pulmonale secondary to polyostotic fibrous dysplasia.

    Science.gov (United States)

    Narayan, Rajeev L; Maldjian, Pierre D

    2009-01-09

    Polyostotic fibrous dysplasia is a rare benign pathological condition of bone in which proliferation of fibrous and osteoid elements results in expansile deformities of the skeleton. We present a case of polyostotic fibrous dysplasia in a young man in whom the severe deformities of the chest wall and spine produced restrictive lung disease, cor pulmonale and respiratory failure.

  14. 47 CFR 54.507 - Cap.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Cap. 54.507 Section 54.507 Telecommunication... Universal Service Support for Schools and Libraries § 54.507 Cap. (a) Amount of the annual cap. The annual funding cap on federal universal service support for schools and libraries shall be $2.25 billion per...

  15. 47 CFR 54.623 - Cap.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Cap. 54.623 Section 54.623 Telecommunication... Universal Service Support for Health Care Providers § 54.623 Cap. (a) Amount of the annual cap. The annual cap on federal universal service support for health care providers shall be $400 million per funding...

  16. Overlap Technique for End-Cap Seals on Cylindrical Magnetic Shields

    CERN Document Server

    Malkowski, S; Boissevain, J; Daurer, C; Filippone, B W; Hona, B; Plaster, B; Woods, D; Yan, H

    2013-01-01

    We present results from studies of the effectiveness of an overlap technique for forming a magnetic seal across a gap at the boundary between a cylindrical magnetic shield and an end-cap. In this technique a thin foil of magnetic material overlaps the two surfaces, thereby spanning the gap across the cylinder and the end-cap, with the magnetic seal then formed by clamping the thin magnetic foil to the surfaces of the cylindrical shield and the end-cap on both sides of the gap. In studies with a prototype 31-cm diameter, 91-cm long, 0.16-cm thick cylindrical magnetic shield and flared end-cap, the magnetic shielding performance of our overlap technique is comparable to that obtained with the conventional method in which the end-cap is placed in direct lapped contact with the cylindrical shield via through bolts or screws.

  17. Preparation and characterization of NaOH treated micro-fibrous polyethylene terephthalate nonwovens for biomedical application.

    Science.gov (United States)

    Hadjizadeh, Afra; Ajji, Abdellah; Bureau, Martin N

    2010-11-01

    Recently, micro-fibrous polyethylene terephthalate nonwovens have been investigated and applied in many biotechnological and biomedical applications. NaOH treatment has been used as a simple and cost effective method to alter surface properties, in order to overcome their surface inertness. However, the effects of this treatment on the matrices mechanical and physical properties; particularly, those composed of fibers with small diameter (<20 microm); have been poorly investigated. This study investigates the variations, imposed by the NaOH treatment, in the physical and tensile properties of micro-fibrous polyethylene terephthalate mats. Polyethylene terephthalate webs with two different average fiber diameters of 6+/-2.5 and 10+/-4 microm were produced by melt blowing process. A number of these webs were consolidated to prepare fibrous matrices using a thermal treatment. The matrices were treated using NaOH 1 N at 65 degrees C for various durations (ranging from 20 min to 24 h). In addition to their physical properties such as weight loss, thickness, porosity, shrinkage and surface density; their morphology and tensile properties were also evaluated using scanning electron microscopy and micromechanical tester, respectively. In general, by increasing treatment duration, weight loss, porosity, and shrinkage increased, while thickness and density decreased. As a result of treatment duration, pores appeared on the surface of individual fibers, and tensile stress and Young's modulus decreased while tensile strain increased. Mats with different fiber diameters showed different physical and mechanical properties. These findings suggested that the structure of the matrices and the properties required for its end use, for biomedical applications including scaffolding materials for tissue engineering, should be considered in selecting NaOH treatment condition. (c) 2010. Published by Elsevier Ltd.

  18. Method for removing strongly adsorbed surfactants and capping agents from metal to facilitate their catalytic applications

    Energy Technology Data Exchange (ETDEWEB)

    Adzic, Radoslav R.; Gong, Kuanping; Cai, Yun; Wong, Stanislaus; Koenigsmann, Christopher

    2016-11-08

    A method of synthesizing activated electrocatalyst, preferably having a morphology of a nanostructure, is disclosed. The method includes safely and efficiently removing surfactants and capping agents from the surface of the metal structures. With regard to metal nanoparticles, the method includes synthesis of nanoparticle(s) in polar or non-polar solution with surfactants or capping agents and subsequent activation by CO-adsorption-induced surfactant/capping agent desorption and electrochemical oxidation. The method produces activated macroparticle or nanoparticle electrocatalysts without damaging the surface of the electrocatalyst that includes breaking, increasing particle thickness or increasing the number of low coordination sites.

  19. Fibrous dysplasia of bone: craniofacial and dental implications.

    Science.gov (United States)

    Burke, A B; Collins, M T; Boyce, A M

    2016-08-05

    Fibrous dysplasia (FD) is a rare bone disease caused by postzygotic somatic activating mutations in the GNAS gene, which lead to constitutive activation of adenylyl cyclase and elevated levels of cyclic AMP, which act on downstream signaling pathways and cause normal bone to be replaced with fibrous tissue and abnormal (woven) bone. The bone disease may occur in one bone (monostotic), multiple bones (polyostotic), or in combination with hyperfunctioning endocrinopathies and hyperpigmented skin lesions (in the setting of McCune-Albright Syndrome). FD is common in the craniofacial skeleton, causing significant dysmorphic features, bone pain, and dental anomalies. This review summarizes the pathophysiology, clinical findings, and treatment of FD, with an emphasis on the craniofacial and oral manifestations of the disease.

  20. 3D CHARACTERIZATION OF WOOD BASED FIBROUS MATERIALS: AN APPLICATION

    Directory of Open Access Journals (Sweden)

    Jérôme Lux

    2011-05-01

    Full Text Available Morphological characterization of wood based fibrous materials is carried out using X-ray tomography. This technique allows the non destructive observation at the scales of a fibre (microscopic scale and of a network of fibres (mesoscopic scale. The 3D images are processed using classical tools of mathematical morphology. Measures of porosities and estimations of the size distributions of fibres and pores are carried out and compared to other results. An alternative method for the calculation of the local orientation of the fibres is also described to quantify the anisotropy of the fibres network. Finally, the individualization of the fibres is obtained from the representation of the fibrous network as a 3D skeleton, making possible further measurements on the isolated fibres.

  1. Retroperitoneal calcifying fibrous tumor mimicking an adrenal tumor.

    Science.gov (United States)

    Prochaska, Erica C; Sciallis, Andrew P; Miller, Barbra S

    2016-06-01

    Establishing the etiology of a retroperitoneal tumor may be difficult due to close proximity of multiple organs. Evaluation of retroperitoneal tumors often leads to surgery, many times to obtain a definitive diagnosis and rule out malignancy. Calcifying fibrous tumors (CFT) are very rare soft tissue tumors occurring most often in young patients. They are most often found arising in the thoracic cavity, mediastinum, abdominal cavity and extremities and usually have a benign clinical course. Macrocscopically, the tumors are well circumscribed and firm with a white-tan appearance. Histologically, CFT comprised a hypocellular proliferation of bland spindle cells, densely hyalinized collagen, chronic lymphoplasmacytic inflammation and dystrophic calcifications. Other considerations in the pathologic differential diagnosis include solitary fibrous tumor and inflammatory myofibroblastic tumor.

  2. The aerosol penetration through an electret fibrous filter

    Institute of Scientific and Technical Information of China (English)

    Jiang Wei; Cheung Chun-Shun; Chan Cheong-Ki; Zhu Chao

    2006-01-01

    The aim of this paper is to present a theoretical study of the aerosol penetration through an electret fibrous filter, using a numerical approach. The aerosol sizes considered in this study were in the submicron range, and in the numerical model, the conventional mechanical mechanisms (impaction, interception, diffusion and gravitationally settling) were taken into consideration along with the electrostatic mechanisms, including the Coulombic and dielectrophoretic effects. The aerosol penetration through an electret fibrous filter is heavily dependent on the aerosol penetration of a single fibre. The aerosol penetration through a single electret fibre under various filtration conditions was calculated. The effects of aerosol diameter, aerosol and fibre charge state, face velocity, packing density and aerosol dielectric constant on the aerosol penetration were investigated.

  3. Clinical guidelines for the management of craniofacial fibrous dysplasia

    Directory of Open Access Journals (Sweden)

    Lee JS

    2012-05-01

    Full Text Available Abstract Fibrous dysplasia (FD is a non-malignant condition caused by post-zygotic, activating mutations of the GNAS gene that results in inhibition of the differentiation and proliferation of bone-forming stromal cells and leads to the replacement of normal bone and marrow by fibrous tissue and woven bone. The phenotype is variable and may be isolated to a single skeletal site or multiple sites and sometimes is associated with extraskeletal manifestations in the skin and/or endocrine organs (McCune-Albright syndrome. The clinical behavior and progression of FD may also vary, thereby making the management of this condition difficult with few established clinical guidelines. This paper provides a clinically-focused comprehensive description of craniofacial FD, its natural progression, the components of the diagnostic evaluation and the multi-disciplinary management, and considerations for future research.

  4. Development of flame resistant treatment for Nomex fibrous structures

    Science.gov (United States)

    Toy, M. S.

    1977-01-01

    Flame resistant fibrous materials for space shuttle application were developed through chemical modification of commercially available aromatic polyamide fibrous products. The new surface treatment was achieved in the laboratory by ultraviolet activation of the fabric in the presence of fluoroolefin monomers and a diluent gas. The monomers grafted under these conditions provide the improved properties of the fabric in flame resistance, chemical inertness, and nonwettability without the sacrifice of color or physical properties. The laboratory reaction vessel was scaled-up to a batch continuous process, which treats ten yards of the commercial width textiles. The treated commercial width Nomex (HT-10-41) from the scaled-up reactor is self-extinguishing in an oxygen-enriched environment, water-repellent, soft, silky, and improved in chemical resistance. Unlike most textile processes, the grafting unit operates under dry conditions and no chemical by-products have to be washed out of the finished product.

  5. Aging-caused changes in optical anisotropy of fibrous tissues

    Science.gov (United States)

    Mikhailova, Alyona D.; Ermolenko, Sergey B.; Zimnyakov, Dmitry A.; Angelsky, Oleg V.

    2009-10-01

    Energy density approach as a modification of the coherent potential approximation was applied to analyze the influence of aging-caused changes in the fibrous tissue on its birefringence. The real fibrous tissue such as tendon was modeled by disordered array of partially oriented dielectric cylinders illuminated by a normally incident linearly polarized plane wave. The supraspinatus human tendon was taken as an object for theoretical modeling. The morphological features of the studied tissue were considered for a system of collagen fiber bundles embedded in a carbohydrate matrix. The latter one is a mixture of glycosaminoglycans and proteoglycans. Age-caused changes of the fibers and matrix influence on the spectral dependence of optical anisotropy spectrum.

  6. Fibrous dysplasia as a rare cause of nasolacrimal duct obstruction

    Directory of Open Access Journals (Sweden)

    Bahtiyar Polat

    2015-09-01

    Full Text Available Fibrous dysplasia of the paranasal sinuses is mostly asymptomatic, but sometimes may cause signs and symptoms de- pending on its location. We report two cases of maxillary fibrous dysplasia obstructing the lacrimal drainage system as a reason of chronic dacryocystitis, and reviewed the related literature. The first case underwent an endonasal endoscopic approach combined with external dacryocystorhinostomy. He had a patent lacrimal system at one-year follow-up. The le- sion was completely removed via an endonasal endoscopic approach in the second case, wherein the patient was asymp- tomatic of the six-month follow-up period. [Arch Clin Exp Surg 2015; 4(3.000: 172-175

  7. [Solitary fibrous tumor of endometrium--a case report].

    Science.gov (United States)

    Dvořák, O; Dvořáková, E; Laco, J; Spaček, J

    2013-06-01

    Solitary fibrous tumor (SFT) is an uncommon mesenchymal tumor. We present a case of SFT occurring in endometrium. Case report. Department of Obstetrics and Gynecology, The Fingerland Department of Pathology, Medical Faculty of Charles University and Faculty Hospital Hradec Králové. We report a case of 57 years old woman with SFT arising from the endometrium, which was diagnosed and treated at our department. Histological finding was supported by typical immunohistochemical profile of the tumor. Aggressive nature of the tumor wasnt showed. The patient underwent abdominal hysterectomy with bilateral adnexectomy and is followed up in regular periods. Occurence of solitary fibrous tumor (SFT) in the female genital tract is extremely rare. To the best of our knowledge, we report the first case of SFT occurring in endometrium. Because of potencial aggressive behaviour of the tumor complete surgical excision and close follow-up is highly recommended.

  8. [Fibrous pseudotumor of the vaginalis testis: report of a case].

    Science.gov (United States)

    Joual, A; Rabii, R; Guessous, H; Benjelloun, M; el Mrini, M; Benjelloun, S

    2000-06-01

    In this study, the authors have reported a case of a benign fibrous pseudotumor of the tunica vaginalis testis in a 24-year old man who was admitted with a left scrotal mass. Scrotal ultrasound and surgical investigation demonstrated the presence of a left testicular tumor; radical orchiectomy was performed by inguinal route. Microscopic examination revealed a pseudotumor of the testicular tunica vaginalis. As this is an uncommon lesion and preoperative diagnosis is difficult, unnecessary radical orchidectomy is often carried out.

  9. Focal fibrous overgrowths: A case series and review of literature

    OpenAIRE

    Kolte, Abhay P.; Rajshri A Kolte; Shrirao, Tushar S.

    2010-01-01

    Intraoral fibrous overgrowths of the soft tissues are relatively common and may be benign reactive or neoplastic lesions. A series of 10 lesions is presented which included pyogenic granuloma, fibroma and peripheral ossifying fibroma. Almost all the lesions occurred in the second and third decades and were present in the anterior segment of the jaws, with a distinct female predilection. Majority of these lesions were asymptomatic and the patients reported for treatment only due to the discomf...

  10. Solitary Fibrous Tumors and So-Called Hemangiopericytoma

    Directory of Open Access Journals (Sweden)

    Nicolas Penel

    2012-01-01

    Full Text Available We have reviewed the literature data regarding the spectrum of tumors including solitary fibrous tumor and hemangiopericytoma with special focus on definition of the disease, discussion of the criteria for malignancy, and the key elements of standard treatment of localized disease. We have discussed the emerging concepts on the tumor biology and the different systemic treatments (chemotherapy and molecular-targeted therapies.

  11. The ultrastructure of malignant fibrous histiocytoma (case report).

    Science.gov (United States)

    Lombardi, L; Pilotti, S; Carbone, A; Rilke, F

    1977-01-01

    A soft tissue malignant fibrous histiocytoma was studied by light and electron microscopy. The presence of fibroblast-like cells, histiocyte-like cells, undifferentiated stem cells, and xanthomatous cells was confirmed. Fibroblast- and histiocyte-like multinucleated giant cells were also observed. The observation of lysosomes in some fibroblast-like cells, the features of undifferentiated stem cells, and the presence of cells and intermediate characteristics common to xanthomatous, histiocytic, and stem cells suggest a strict relationship among these cellular types.

  12. Affine kinematics in planar fibrous connective tissues: an experimental investigation.

    Science.gov (United States)

    Jayyosi, C; Affagard, J-S; Ducourthial, G; Bonod-Bidaud, C; Lynch, B; Bancelin, S; Ruggiero, F; Schanne-Klein, M-C; Allain, J-M; Bruyère-Garnier, K; Coret, M

    2017-03-29

    The affine transformation hypothesis is usually adopted in order to link the tissue scale with the fibers scale in structural constitutive models of fibrous tissues. Thanks to the recent advances in imaging techniques, such as multiphoton microscopy, the microstructural behavior and kinematics of fibrous tissues can now be monitored at different stretching within the same sample. Therefore, the validity of the affine hypothesis can be investigated. In this paper, the fiber reorientation predicted by the affine assumption is compared to experimental data obtained during mechanical tests on skin and liver capsule coupled with microstructural imaging using multiphoton microscopy. The values of local strains and the collagen fibers orientation measured at increasing loading levels are used to compute a theoretical estimation of the affine reorientation of collagen fibers. The experimentally measured reorientation of collagen fibers during loading could not be successfully reproduced with this simple affine model. It suggests that other phenomena occur in the stretching process of planar fibrous connective tissues, which should be included in structural constitutive modeling approaches.

  13. Fibrous tissues growth and remodeling: Evolutionary micro-mechanical theory

    Science.gov (United States)

    Lanir, Yoram

    2017-10-01

    Living fibrous tissues are composite materials having the unique ability to adapt their size, shape, structure and mechanical properties in response to external loading. This adaptation, termed growth and remodeling (G&R), occurs throughout life and is achieved via cell-induced turnover of tissue constituents where some are degraded and new ones are produced. Realistic mathematical modeling of G&R provides insight into the basic processes, allows for hypotheses testing, and constitutes an essential tool for establishing clinical thresholds of pathological remodeling and for the production of tissue substitutes aimed to achieve target structure and properties. In this study, a general 3D micro-mechanical multi-scale theory of G&R in fibrous tissue was developed which connects between the evolution of the tissue structure and properties, and the underlying mechano-biological turnover events of its constituents. This structural approach circumvents a fundamental obstacle in modeling growth mechanics since the growth motion is not bijective. The model was realized for a flat tissue under two biaxial external loadings using data-based parameter values. The predictions show close similarity to characteristics of remodeled adult tissue including its structure, anisotropic and non-linear mechanical properties, and the onset of in situ pre-strain and pre-stress. The results suggest that these important features of living fibrous tissues evolve as they grow.

  14. Erosive separation of organic coatings from fibrous substrates.

    Science.gov (United States)

    Weiss, M; Momber, A W

    2004-11-01

    The separation of organic coatings from fibrous substrates is a key problem in recycling processes. This problem applies to carpets, technical textiles and automotive interior components. This paper reports about results of laboratory studies involving the application of high-speed liquid jets to solve this problem. Results from high-speed video images are used to qualify the principal erosion process. It is shown that the coating material is first ground by the jet; the generated erosion debris is then pushed through the permeable fibrous fabric of the substrate. It is also found that threshold conditions exist for the coating grinding process and for the debris transportation. These threshold conditions depend on target composition and process parameters. A phenomenological separation model is introduced. The influence of key process parameters, namely jet velocity, exposure time, stand-off distance and impact angle, is also investigated. It is found that high-speed liquid jets are suitable tools for separating organic coatings completely and selectively from fibrous substrates. Recommendations on how to optimise the erosion process are derived from the results.

  15. Monostotic fibrous dysplasia of the metacarpal: a case report

    Directory of Open Access Journals (Sweden)

    Kátia Tôrres Batista

    Full Text Available ABSTRACT Fibrous dysplasia is a bone disease characterized by abnormal differentiation of fibrous tissue in the bones; it is often asymptomatic. It may affect one bone (monostotic or several bones (polyostotic. The monostotic form primarily affects the ribs, but hardly ever affects the hand. It is important to make the differential diagnosis with malignant bone tumors. This article describes the treatment and outcome of a rare case of a patient admitted with a history of tumor growth in the right hand, diagnosed as fibrous dysplasia of the right second metacarpal. Male patient, 14 years of age, admitted to the Sarah Hospital with lesion on the dorsum of the right hand without pain complaints, previous history of trauma, nor local signs of inflammation. Physical examination revealed swelling on the dorsum of the second metacarpal, painless, with unaltered mobility and sensitivity. Radiography, computed tomography, and magnetic resonance imaging indicated the involvement of the entire length of the second metacarpal: only the distal epiphysis was preserved, with areas of bone lysis. After biopsy confirmation, the patient underwent surgery, using a long cortical graft for reconstructing the metacarpal. During the follow-up period of five years there were no signs of recurrence, and proper digital growth and functionality of the operated hand were observed.

  16. Essential Oil Bioactive Fibrous Membranes Prepared via Coaxial Electrospinning.

    Science.gov (United States)

    Yao, Zhi-Cheng; Chen, Si-Cong; Ahmad, Zeeshan; Huang, Jie; Chang, Ming-Wei; Li, Jing-Song

    2017-06-01

    A novel antimicrobial composite material was prepared by encapsulating orange essential oil (OEO) in zein prolamine (ZP) via the coaxial electrospinning (ES) technique. By manipulating process parameters, the morphological features of ZP/OEO fibers were modulated. Fine fibers with diameters ranging from 0.7 to 2.3 μm were obtained by regulating ZP solution concentration and process parameters during the ES process. Optimal loading capacity (LC) and encapsulation efficiency (EE) of OEO in fibrous ZP mats were determined to be 22.28% and 53.68%, respectively, and were achieved using a 35 w/v% ZP ES solution. The encapsulation of OEO was found to be reliant on ZP solution concentration (the enveloping medium). SEM analysis indicates the surface morphology of ZP/OEO electrospun fibers is dependent on ZP solution loading volume, with lower ZP concentrations yielding defective fibrous structures (for example, beaded and spindled-string like morphologies). Furthermore, this loading volume also influences OEO LC, EE, mat water contact angle and oil retention. CCK-8 assay and cell morphology assessment (HEK293T cells) indicate no significant change with electrospun ZP and ZP/OEO fibrous membranes over an 8 h period. Antimicrobial activity assessment using Escherichia coli, suggests composite nonwovens possess sterilization properties; elucidating potential application in active food packaging, food preservation and therefore sustainability. © 2017 Institute of Food Technologists®.

  17. Feed Technology of Fibrous Sugarcane Residues for Ruminants

    Directory of Open Access Journals (Sweden)

    Kuswandi

    2007-06-01

    Full Text Available Abundant sugarcane residue during shortage of roughage in dry season gives an opportunity to raise ruminants around sugarcane industries. However, these products are not widely used by farmers due to an assumption that the usage is inefficient and that the feed utilization technology is not widely recognized. Sugarcane fibrous residues (tops, bagasse and pith may be a potential feed component if pre-treated to increase its digestion and consumption by the animal, and/or supplemented by other ingredients to balance nutrients in the rumen as well as those for production purpose. Digestibility can be increased by chemical treatments such as ammoniation and other alkaline treatments, whereas consumption can be increased by physical treatments such as grinding, hammermilling or pelleting. Nutrients that are missing in these fibrous residues can be provided by addition of urea, molasses and minerals for maintenance need, and bypass nutrients (carbohydrates, protein and fats that are digested in the small intestine and available for tissue or milk synthesis. There are three options for development of livestock agribusiness based on fibrous sugarcane residues; however, these require several technologies to optimize the utilization of these residues.

  18. Numerical Modeling of the Last Glacial Maximum Yellowstone Ice Cap Captures Asymmetry in Moraine Ages

    Science.gov (United States)

    Anderson, L. S.; Wickert, A. D.; Colgan, W. T.; Anderson, R. S.

    2014-12-01

    The Last Glacial Maximum (LGM) Yellowstone Ice Cap was the largest continuous ice body in the US Rocky Mountains. Terminal moraine ages derived from cosmogenic radionuclide dating (e.g., Licciardi and Pierce, 2008) constrain the timing of maximum Ice Cap extent. Importantly, the moraine ages vary by several thousand years around the Ice Cap; ages on the eastern outlet glaciers are significantly younger than their western counterparts. In order to interpret these observations within the context of LGM climate in North America, we perform two numerical glacier modeling experiments: 1) We model the initiation and growth of the Ice Cap to steady state; and 2) We estimate the range of LGM climate states which led to the formation of the Ice Cap. We use an efficient semi-implicit 2-D glacier model coupled to a fully implicit solution for flexural isostasy, allowing for transient links between climatic forcing, ice thickness, and earth surface deflection. Independent of parameter selection, the Ice Cap initiates in the Absaroka and Beartooth mountains and then advances across the Yellowstone plateau to the west. The Ice Cap advances to its maximum extent first to the older eastern moraines and last to the younger western and northwestern moraines. This suggests that the moraine ages may reflect the timescale required for the Ice Cap to advance across the high elevation Yellowstone plateau rather than the timing of local LGM climate. With no change in annual precipitation from the present, a mean summer temperature drop of 8-9° C is required to form the Ice Cap. Further parameter searches provide the full range of LGM paleoclimate states that led to the Yellowstone Ice Cap. Using our preferred parameter set, we find that the timescale for the growth of the complete Ice Cap is roughly 10,000 years. Isostatic subsidence helps explain the long timescale of Ice Cap growth. The Yellowstone Ice Cap caused a maximum surface deflection of 300 m (using a constant effective elastic

  19. Biodegradable fibrous scaffolds with tunable properties formed from photo-cross-linkable poly(glycerol sebacate).

    Science.gov (United States)

    Ifkovits, Jamie L; Devlin, Jeffrey J; Eng, George; Martens, Timothy P; Vunjak-Novakovic, Gordana; Burdick, Jason A

    2009-09-01

    It is becoming increasingly apparent that the architecture and mechanical properties of scaffolds, particularly with respect to mimicking features of natural tissues, are important for tissue engineering applications. Acrylated poly(glycerol sebacate) (Acr-PGS) is a material that can be cross-linked upon exposure to ultraviolet light, leading to networks with tunable mechanical and degradation properties through simple changes during Acr-PGS synthesis. For example, the number of acrylate functional groups on the macromer dictates the concentration of cross-links formed in the resulting network. Three macromers were synthesized that form networks that vary dramatically with respect to their tensile modulus ( approximately 30 kPa to 6.6 MPa) and degradation behavior ( approximately 20-100% mass loss at 12 weeks) based on the extent of acrylation ( approximately 1-24%). These macromers were processed into biodegradable fibrous scaffolds using electrospinning, with gelatin as a carrier polymer to facilitate fiber formation and cell adhesion. The resulting scaffolds were also diverse with respect to their mechanics (tensile modulus ranging from approximately 60 kPa to 1 MPa) and degradation ( approximately 45-70% mass loss by 12 weeks). Mesenchymal stem cell adhesion and proliferation on all fibrous scaffolds was indistinguishable from those of controls. The scaffolds showed similar diversity when implanted on the surface of hearts in a rat model of acute myocardial infarction and demonstrated a dependence on the scaffold thickness and chemistry in the host response. In summary, these diverse scaffolds with tailorable chemical, structural, mechanical, and degradation properties are potentially useful for the engineering of a wide range of soft tissues.

  20. Retrospective Analysis of NIST Standard Reference Material 1450, Fibrous Glass Board, for Thermal Insulation Measurements.

    Science.gov (United States)

    Zarr, Robert R; Heckert, N Alan; Leigh, Stefan D

    2014-01-01

    Thermal conductivity data acquired previously for the establishment of Standard Reference Material (SRM) 1450, Fibrous Glass Board, as well as subsequent renewals 1450a, 1450b, 1450c, and 1450d, are re-analyzed collectively and as individual data sets. Additional data sets for proto-1450 material lots are also included in the analysis. The data cover 36 years of activity by the National Institute of Standards and Technology (NIST) in developing and providing thermal insulation SRMs, specifically high-density molded fibrous-glass board, to the public. Collectively, the data sets cover two nominal thicknesses of 13 mm and 25 mm, bulk densities from 60 kg·m(-3) to 180 kg·m(-3), and mean temperatures from 100 K to 340 K. The analysis repetitively fits six models to the individual data sets. The most general form of the nested set of multilinear models used is given in the following equation: [Formula: see text]where λ(ρ,T) is the predicted thermal conductivity (W·m(-1)·K(-1)), ρ is the bulk density (kg·m(-3)), T is the mean temperature (K) and ai (for i = 1, 2, … 6) are the regression coefficients. The least squares fit results for each model across all data sets are analyzed using both graphical and analytic techniques. The prevailing generic model for the majority of data sets is the bilinear model in ρ and T. [Formula: see text] One data set supports the inclusion of a cubic temperature term and two data sets with low-temperature data support the inclusion of an exponential term in T to improve the model predictions. Physical interpretations of the model function terms are described. Recommendations for future renewals of SRM 1450 are provided. An Addendum provides historical background on the origin of this SRM and the influence of the SRM on external measurement programs.

  1. Two-Scale Modeling Approach to Predict Permeability of Fibrous Media

    Directory of Open Access Journals (Sweden)

    Sudhakar Jaganathan

    2008-06-01

    Full Text Available We previously demonstrated how one can develop a 3-D geometry to model the fibrous microstructure of a nonwoven fiberweb and use it to simulate its permeability at fiber level [1-6]. Developing 3-D models of most nonwoven fabrics (bonded fiberwebs, however, is cumbersome, as in the case of hydroentangled fabrics, for instance. In such cases, microscopic techniques are often used to generate 3-D images of the media’s microstructures. Nevertheless, whether the microstructure is modeled or obtained from 3-D imaging, extensive computational resources are required to use them in fluid flow simulations [7]. To circumvent this problem, a two-scale modeling approach is proposed here that allows us to simulate the entire thickness of a commercial fabric/filter on a personal computer. In particular, the microscale permeability of a hydroentangled nonwoven is computed using 3-D reconstructed microstructures obtained from Digital Volumetric Imaging (DVI. The resulting microstructural permeability tensors are then used in a macroscale porous model to simulate the flow through the material’s thickness and the calculation of its overall permeability.

  2. Coronary artery disease associated transcription factor TCF21 regulates smooth muscle precursor cells that contribute to the fibrous cap

    Directory of Open Access Journals (Sweden)

    S.T. Nurnberg

    2015-09-01

    Full Text Available TCF21 is a basic helix–loop–helix transcription factor that has recently been implicated as contributing to susceptibility to coronary heart disease based on genome wide association studies. In order to identify transcriptionally regulated target genes in a major disease relevant cell type, we performed siRNA knockdown of TCF21 in in vitro cultured human coronary artery smooth muscle cells and compared the transcriptome of siTCF21 versus siCONTROL treated cells. The raw (FASTQ as well as processed (BED data from 3 technical replicates per treatment has been deposited with Gene Expression Omnibus (GSE44461.

  3. Effect of residual stress on peak cap stress in arteries.

    Science.gov (United States)

    Vandiver, Rebecca

    2014-10-01

    Vulnerable plaques are a subset of atherosclerotic plaques that are prone to rupture when high stresses occur in the cap. The roles of residual stress, plaque morphology, and cap stiffness on the cap stress are not completely understood. Here, arteries are modeled within the framework of nonlinear elasticity as incompressible cylindrical structures that are residually stressed through differential growth. These structures are assumed to have a nonlinear, anisotropic, hyperelastic response to stresses in the media and adventitia layers and an isotropic response in the intima and necrotic layers. The effect of differential growth on the peak stress is explored in a simple, concentric geometry and it is shown that axial differential growth decreases the peak stress in the inner layer. Furthermore, morphological risk factors are explored. The peak stress in residually stressed cylinders is not greatly affected by changing the thickness of the intima. The thickness of the necrotic layer is shown to be the most important morphological feature that affects the peak stress in a residually stressed vessel.

  4. Catastrophic antiphospholipid syndrome (CAPS): update from the 'CAPS Registry'.

    Science.gov (United States)

    Cervera, R

    2010-04-01

    Although less than 1% of patients with the antiphospholipid syndrome (APS) develop the catastrophic variant, its potentially lethal outcome emphasizes its importance in clinical medicine today. However, the rarity of this variant makes it extraordinarily difficult to study in any systematic way. In order to put together all of the published case reports as well as the new diagnosed cases from all over the world, an international registry of patients with catastrophic APS (CAPS Registry) was created in 2000 by the European Forum on Antiphospholipid Antibodies (see http://www.med.ub.es/MIMMUN/FORUM/CAPS.HTM). Currently, it documents the entire clinical, laboratory and therapeutic data of more than 300 patients whose data has been fully registered.

  5. 21 CFR 884.5250 - Cervical cap.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Cervical cap. 884.5250 Section 884.5250 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES... cap. (a) Identification. A cervical cap is a flexible cuplike receptacle that fits over the cervix to...

  6. 21 CFR 888.3000 - Bone cap.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Bone cap. 888.3000 Section 888.3000 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES Prosthetic Devices § 888.3000 Bone cap. (a) Identification. A bone cap is a mushroom...

  7. CMS end-cap yoke detector

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    The magnetic flux generated by the superconducting coil in the CMS detector is returned via an iron yoke comprising three end-cap discs at each end (end-cap yoke) and five concentric cylinders (barrel yoke). This picture shows the first of three end-cap discs (red) seen through the outer cylinder of the vacuum tank which will house the superconducting coil.

  8. ATLAS End Cap toroid in upstanding position

    CERN Multimedia

    2005-01-01

    End Cap toroid The ATLAS End Cap toroid weights 240-ton and is 12-m diameter high. The parts of this vacuum vessel had to be integrated and tested so that End Cap Toroid has no leaks. After that it could be cooled down to 80 K.

  9. Motion of polar cap arcs

    Science.gov (United States)

    Hosokawa, K.; Moen, J. I.; Shiokawa, K.; Otsuka, Y.

    2011-01-01

    A statistics of motion of polar cap arcs is conducted by using 5 years of optical data from an all-sky imager at Resolute Bay, Canada (74.73°N, 265.07°E). We identified 743 arcs by using an automated arc detection algorithm and statistically examined their moving velocities as estimated by the method of Hosokawa et al. (2006). The number of the arcs studied is about 5 times larger than that in the previous statistics of polar cap arcs by Valladares et al. (1994); thus, we could expect to obtain more statistically significant results. Polar cap arcs are found to fall into two distinct categories: the By-dependent and By-independent arcs. The motion of the former arcs follows the rule reported by Valladares et al. (1994), who showed that stable polar cap arcs move in the direction of the interplanetary magnetic field (IMF) By. About two thirds of the arcs during northward IMF conditions belong to this category. The latter arcs always move poleward irrespective of the sign of the IMF By, which possibly correspond to the poleward moving arcs in the morning side reported by Shiokawa et al. (1997). At least one third of the arcs belong to this category. The By-dependent arcs tend to move faster when the magnitude of the IMF By is larger, suggesting that the transport of open flux by lobe reconnection from one polar cap compartment to the other controls their motion. In contrast, the speed of the By-independent arcs does not correlate with the magnitude of the By. The motions of both the By-dependent and By-independent arcs are most probably caused by the magnetospheric convection. Convection in the region of By-dependent arcs is affected by the IMF By, which indicates that their sources may be on open field lines or in the closed magnetosphere adjacent to the open-closed boundary, whereas By-independent arcs seem to be well on closed field lines. Hence, the magnetospheric source of the two types of arc may be different. This implies that the mechanisms causing the

  10. A Reduction Factor for Buckling Load of Spherical Cap Shells

    Directory of Open Access Journals (Sweden)

    P.N. Khakina

    2011-12-01

    Full Text Available The classical buckling theory usually overestimates the buckling load of shells. In this study, a reduction factor is determined using geometrical parameters so as to reduce the classical buckling load to a more realistic value based on the post-buckling load. It is observed that the buckling load is directly proportional to the thickness and rise and inversely proportional to the span of the spherical cap. Finite element modeling and simulation using ABAQUS was conducted to determine the buckling behavior of a spherical cap shell subjected to different initial geometrical imperfections. The load-deflection curves drawn from the simulation formed a plateau at the post-buckling load. It is observed that as the initial geometrical imperfection is increased, the value of the initial buckling load is almost the same as the value of the post-buckling load on the plateau. The results obtained from different shells were used to derive a formula for the reduction factor.

  11. Capping of rare earth silicide nanowires on Si(001)

    Energy Technology Data Exchange (ETDEWEB)

    Appelfeller, Stephan; Franz, Martin; Kubicki, Milan; Dähne, Mario [Institut für Festkörperphysik, Technische Universität Berlin, 10623 Berlin (Germany); Reiß, Paul; Niermann, Tore; Lehmann, Michael [Institut für Optik und Atomare Physik, Technische Universität Berlin, 10623 Berlin (Germany); Schubert, Markus Andreas [IHP–Leibniz-Institut für innovative Mikroelektronik, 15236 Frankfurt (Oder) (Germany)

    2016-01-04

    The capping of Tb and Dy silicide nanowires grown on Si(001) was studied using scanning tunneling microscopy and cross-sectional high-resolution transmission electron microscopy. Several nanometers thick amorphous Si films deposited at room temperature allow an even capping, while the nanowires maintain their original structural properties. Subsequent recrystallization by thermal annealing leads to more compact nanowire structures and to troughs in the Si layer above the nanowires, which may even reach down to the nanowires in the case of thin Si films, as well as to V-shaped stacking faults forming along (111) lattice planes. This behavior is related to strain due to the lattice mismatch between the Si overlayer and the nanowires.

  12. Magnetic properties of ultrathin Ni81Fe19 films with Ta and Ru capping layers.

    Science.gov (United States)

    Kezilebieke, S; Ali, M; Shadeke, B; Gunnella, R

    2013-11-27

    Magnetic properties of Ni81Fe19 (permalloy) ultrathin films with Ru and Ta capping layers (CLs) were investigated for applications to magnetic random access memory units (MRAM). The sample structure, which simulated an MRAM free layer, is Si- sub./SiO2/Ni81Fe19/Ru(Ta). The Ni81Fe19 thin films less than 3 nm thick with Ru CL show low coercive fields compared with the Ta capping layer. Both systems showed loss of momentum equivalent to magnetically dead layers of thickness (δ) ~0.6 nm for Ru cap layer and ~1.4 nm for Ta cap layer, respectively. Moreover, after annealing the thicknesses are slightly increased to an equivalent magnetic dead layer thickness of δ ~0:84 nm and ~1.80 nm for Ru and Ta CL, respectively. Our calculations showed that the presence of only 11% Ta concentration at the interface reduced the Ni momentum to zero, with the Ni–Ta coupling being anti-ferromagnetic; while 50% Ru intermixing at the interface reduced the Ni momentum to zero with the coupling between Ru and Ni being ferromagnetic. To find out more about the intermixing at the interface, the composition and chemical states were characterized by the x-ray photoelectron spectroscopy and peak decomposition technique. The result showed that the peak positions were different from the pure metallic case at the interface region, mainly because of the intermixing between two layers. In conclusion, the Ru capping layer might be important for MRAM use in terms of low coercive field and small δ layer thickness if compared with the Ta capping layer.

  13. Magnetic properties of ultrathin Ni81Fe19 films with Ta and Ru capping layers

    Science.gov (United States)

    Kezilebieke, S.; Ali, M.; Shadeke, B.; Gunnella, R.

    2013-11-01

    Magnetic properties of Ni81Fe19 (permalloy) ultrathin films with Ru and Ta capping layers (CLs) were investigated for applications to magnetic random access memory units (MRAM). The sample structure, which simulated an MRAM free layer, is Si- sub./SiO2/Ni81Fe19/Ru(Ta). The Ni81Fe19 thin films less than 3 nm thick with Ru CL show low coercive fields compared with the Ta capping layer. Both systems showed loss of momentum equivalent to magnetically dead layers of thickness (δ) ˜0.6 nm for Ru cap layer and ˜1.4 nm for Ta cap layer, respectively. Moreover, after annealing the thicknesses are slightly increased to an equivalent magnetic dead layer thickness of δ ˜ 0.84 nm and ˜1.80 nm for Ru and Ta CL, respectively. Our calculations showed that the presence of only 11% Ta concentration at the interface reduced the Ni momentum to zero, with the Ni-Ta coupling being anti-ferromagnetic; while 50% Ru intermixing at the interface reduced the Ni momentum to zero with the coupling between Ru and Ni being ferromagnetic. To find out more about the intermixing at the interface, the composition and chemical states were characterized by the x-ray photoelectron spectroscopy and peak decomposition technique. The result showed that the peak positions were different from the pure metallic case at the interface region, mainly because of the intermixing between two layers. In conclusion, the Ru capping layer might be important for MRAM use in terms of low coercive field and small δ layer thickness if compared with the Ta capping layer.

  14. Hypotrichosis with keratosis pilaris: electrophoretical study of hair fibrous proteins from a patient.

    Science.gov (United States)

    Dekio, S; Nagashima, T; Watanabe, Y; Jidoi, J

    1989-01-01

    S-carboxymethylated (SCM) fibrous proteins from the scalp hair of a patient with hypotrichosis with keratosis pilaris (HTKP) and from that of a normal individual were analyzed using two-dimensional electrophoresis. One SCM fibrous protein component was different electrophoretically in the HTKP patient. It is suggested that the brittleness of the HTKP hair might result from this alteration of the fibrous protein composition of the hair.

  15. Benzonorbornadiene end caps for PMR resins

    Science.gov (United States)

    Panigot, Michael J.; Waters, John F.; Varde, Uday; Sutter, James K.; Sukenik, Chaim N.

    1992-01-01

    Several ortho-disubstituted benzonorbornadiene derivatives are described. These molecules contain acid, ester, or anhydride functionality permitting their use as end caps in PMR (polymerization of monomer reactants) polyimide systems. The replacement of the currently used norbornenyl end caps with benzonorbornadienyl end caps affords resins of increased aromatic content. It also allows evaluation of some mechanistic aspects of PMR cross-linking. Initial testing of N-phenylimide model compounds and of actual resin formulations using the benzonorbornadienyl end cap reveals that they undergo efficient thermal crosslinking to give oligomers with physical properties and thermal stability comparable to commercial norbornene-end-capped PMR systems.

  16. Angiomatoid fibrous histiocytoma in a 25-year-old male

    Directory of Open Access Journals (Sweden)

    David Dingli

    2010-06-01

    Full Text Available Angiomatoid fibrous histiocytoma (AFH is a rare disease that is often misdiagnosed initially. Patients can present with a clinical picture concerning for other diseases, and pathologic review is not always revealing. Molecular diagnostics are increasingly being utilized to detect gene fusions characteristic for AFH. Surgery remains the mainstay of management, and can effectively control local recurrences and metastases. Herein we describe a case report of a 25-year-old gentleman whose presentation was concerning for lymphoma. Subsequently we review of the relevant literature.

  17. Solitary Fibrous Tumor in Bladder:A Case Report

    Institute of Scientific and Technical Information of China (English)

    王涛; 陈瑞宝; 乔建坤; 胡涛; 刘继红; 杨为民; 叶章群

    2010-01-01

    Solitary fibrous tumor(SFT) in bladder is extremely rare.In this study,we reported one case of bladder SFT and reviewed the only ten cases of the disease that had been reported so far.The patient suffered from residual urine sensation and urethral pain.Cystoscopy revealed a 7-cm protruding mass at the dome of the bladder,and bladder mucosa biopsy showed normal differentiation of the bladder mucosa with a small amount of inflammatory cells.Radical resection of the tumor was performed in this patient.Patholog...

  18. Benign fibrous histiocytoma: A rare case involving jaw bone

    Directory of Open Access Journals (Sweden)

    Hitesh Shoor

    2015-01-01

    Full Text Available Benign fibrous histiocytoma (BFH is a soft tissue neoplasm which occurs mostly on the skin of extremities. BFH rarely occurs in bone and may affect femur, tibia, and pelvic bone. Jaw bone involvement is very unusual with only 11 cases reported till date. This report describes a case of BFH occurring in a 30-year-old female patient affecting left mandibular posterior region. Computed tomography revealed a well-defined expansile lytic lesion in the posterior mandible. Gross examination of the tumor revealed an admixture of fibroblasts and histiocytes in a fascicular and storiform pattern. Immunohistochemical staining was positive for CD68.

  19. Benign fibrous histiocytoma: A rare case involving jaw bone.

    Science.gov (United States)

    Shoor, Hitesh; Pai, Keerthilatha M; Shergill, Ankur Kaur; Kamath, Abhay Taranath

    2015-09-01

    Benign fibrous histiocytoma (BFH) is a soft tissue neoplasm which occurs mostly on the skin of extremities. BFH rarely occurs in bone and may affect femur, tibia, and pelvic bone. Jaw bone involvement is very unusual with only 11 cases reported till date. This report describes a case of BFH occurring in a 30-year-old female patient affecting left mandibular posterior region. Computed tomography revealed a well-defined expansile lytic lesion in the posterior mandible. Gross examination of the tumor revealed an admixture of fibroblasts and histiocytes in a fascicular and storiform pattern. Immunohistochemical staining was positive for CD68.

  20. Metastatic melanoma mimicking solitary fibrous tumor: report of two cases.

    Science.gov (United States)

    Bekers, Elise M; van Engen-van Grunsven, Adriana C H; Groenen, Patricia J T A; Westdorp, Harm; Koornstra, Rutger H T; Bonenkamp, Johannes J; Flucke, Uta; Blokx, Willeke A M

    2014-02-01

    Malignant melanomas are known for their remarkable morphological variation and aberrant immunophenotype with loss of lineage-specific markers, especially in recurrences and metastases. Hot spot mutations in BRAF, NRAS, GNAQ, and GNA11 and mutations in KIT are oncogenic events in melanomas. Therefore, genotyping can be a useful ancillary diagnostic tool. We present one case each of recurrent and metastatic melanoma, both showing histological and immunohistochemical features of solitary fibrous tumor (SFT). Mutational analysis detected BRAF and NRAS mutations in the primary and secondary lesions, respectively. This result confirmed the diagnosis of recurrent/metastastic melanoma.

  1. The Experiment of Drying Process of the Fibrous Material

    Directory of Open Access Journals (Sweden)

    Jiří RASZKA

    2015-06-01

    Full Text Available The article describes the experiment of water evaporation from fibrous material (cotton. The material is placed in the tube and hot air flows through (process of drying. Temperature of air is measured by thermocouple. The textile represents porous medium with certain amount of water (wet textile. Porous layer makes pressure drop when airflow starts. Properties of air (temperature, relative humidity change during evaporation process. Values of pressure drop, temperature and humidity measured during experiment are used for set up of boundary condition, porous layer and evaporation model in Ansys Fluent 13.

  2. Aerosol Filtration Application Using Fibrous Media An Industrial Perspective

    Institute of Scientific and Technical Information of China (English)

    杨传芳

    2012-01-01

    Filtration of aerosol particles using non-woven fibrous media is a common practice for air cleaning. It has found wide applications in industries and our daily lives. This paper overviews some of these applications and provides an industrial perspective. It starts from discussing aerosol filtration theory, followed by a brief review on the advancement of filtration media. After that, filtration applications in respiratory protection, dust collection, and engine in-take air cleaning are elaborated. These are the areas that the author sees as the typical needed ones in China's fast pace economical development endeavor, where air filtration enables the protection of human health, environment and equipment for sustainability.

  3. Fibrous harmatoma of infancy in the scrotum: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hee Kyung; Kim, Kyu Soon; Kang, Dong Wook; Lee, Seung Yeon [Eulji University Hospital, Daejeon (Korea, Republic of)

    2017-02-15

    Fibrous hamartoma of infancy (FHI) is a rare, benign subcutaneous tumor occurring mainly before the age of 2 years. The most commonly reported locations of FHI are the extremities such as the shoulder or axilla. However, FHI arising in the genital area is extremely rare and has not been reported with correlated radiologic findings. In this case report, we present a case of 5-month-old male child diagnosed with FHI in the scrotum, with a focus on the correlation between the radiologic and pathologic findings.

  4. Fibrous dysplasia of maxilla: Report of two cases

    Directory of Open Access Journals (Sweden)

    Nisha Dua

    2015-01-01

    Full Text Available Fibrous dysplasia (FD is an idiopathic skeletal disorder in which the trabecular bone is replaced and distorted by poorly organized, structurally unsound fibro-osseous tissue. The lesion is classified into two forms: Monostotic (75-80% and polyostotic. A distinct form of Polyostotic FD, known as McCune-Albright Syndrome, is accompanied by cutaneous pigmentation and sexual precocity, and this occurs almost exclusively in women. Typical radiographic appearance shows an expanded osseous lesion having poorly defined margins covered by a thin "eggshell" cortex and lacking periosteal new bone formation. Here, we are presenting two case reports of FD involving the maxilla.

  5. Craniofacial surgery and optic canal decompression in adult fibrous dysplasia

    Directory of Open Access Journals (Sweden)

    Mahapatra A

    2003-01-01

    Full Text Available A 29-year-old female had a 3-year history of bony swelling over the right frontal area. For 3 months she noticed proptosis of her right eye. Investigations revealed fibrous dysplasia involving the right half of the frontal bone and the right greater and lesser wings of the sphenoid bone. Visual evoked potentials (VEP showed delayed latencies on the involved side. A craniofacial surgery with optic canal decompression was performed. Follow-up after 2 years revealed normalization of VEP.

  6. Solitary fibrous tumor arising in an intrathoracic goiter

    DEFF Research Database (Denmark)

    Larsen, Stine Rosenkilde; Godballe, Christian; Krogdahl, Annelise

    2010-01-01

    . CONCLUSION: The histological appearance and immunohistochemical reaction pattern of SFT is characteristic. The entity should be considered when dealing with a spindle cell lesion in the thyroid gland. All cases of this site of origin reported have had a benign clinical course. As only a small number of cases......BACKGROUND: Solitary fibrous tumor (SFT) is a rare spindle cell tumor most often found in the mediastinal pleura. Nineteen cases of SFT arising in the thyroid gland have been reported. We report a case of SFT of the thyroid gland with immunohistochemical and cytogenetic investigation. SUMMARY: A 58...

  7. Solitary fibrous tumor of the orbit presenting in pregnancy

    Directory of Open Access Journals (Sweden)

    Das Jayanta

    2009-01-01

    Full Text Available A 32-year-old woman, three months pregnant, reported with the complaint of protrusion of the right eye for six months. She gave history of rapid protrusion of eyeball for the last two months along with the history of double vision for the last one month. Computer tomography (CT scan revealed a well-defined mass lesion in the intraconal space of the right orbit which was excised through a lateral orbitotomy approach. Histological examination and immunohistochemistry revealed a solitary fibrous tumor, which showed a rapid progression in pregnancy.

  8. Water balance of two earthen landfill caps in a semi-arid climate

    Energy Technology Data Exchange (ETDEWEB)

    Khire, M.V. [GeoSyntec Consultants, Boca Raton, FL (United States); Benson, C.H.; Bosscher, P.J. [Univ. of Wisconsin, Madison, WI (United States)

    1997-12-31

    Water balance data are presented that were obtained from two earthen cap test sections located in a semi-arid region. The test sections were constructed on a municipal solid waste landfill in East Wenatchee, Washington, USA. One test section represents a traditional resistive barrier, and is constructed with a compacted silty clay barrier 60 cm thick and a vegetated silty clay surface layer 15 cm thick. The other test section represents a capillary barrier and has a sand layer 75 cm thick overlain by a 15-cm-thick vegetated surface layer of silt. Extensive hydrological and meteorological data have been collected since November 1992. Unsaturated hydraulic properties of soils, hydrologic parameters, and vegetation have been extensively characterized. Results of the study show that capillary barriers can be effective caps in semi-arid and arid regions. They are also cheaper to construct and can perform better than traditional resistive barriers.

  9. Structure-induced nonlinear viscoelasticity of non-woven fibrous matrices.

    Science.gov (United States)

    Rizvi, Mohd Suhail; Pal, Anupam; Das, Sovan Lal

    2016-12-01

    Fibrous materials are widely utilized as tissue engineering scaffolds for tissue regeneration and other bioengineering applications. The structural as well as mechanical characteristics of the fibrous matrices under static and dynamic mechanical loading conditions influence the response of the cells. In this paper, we study the mechanical response of the non-woven fibrous matrices under oscillatory loading conditions and its dependence on the structural properties of fibrous matrix. We demonstrate that under oscillatory shear and elongation, the fibrous matrices demonstrate nonlinear viscoelasticity at all strain amplitudes. This is contrary to the behavior of other soft polymeric materials for which nonlinearity in the viscoelastic response vanishes for small strains. These observations suggest that despite their prevalence, the measures of linear viscoelasticity (e.g., storage and loss moduli) are inadequate for the general description of the viscoelastic nature of the fibrous materials. It was, however, found that linear viscoelastic nature of fibrous matrices for small amplitudes is restored when a pre-stretch is applied to the fibrous matrix along with oscillatory strains. Further, we also explored the influence of the structural properties of the fibrous matrices (fiber orientation, alignment and curvature) on their viscoelastic nature.

  10. Epidermal nevus syndrome associated with polyostotic fibrous dysplasia, CNS lipoma, and aplasia cutis

    National Research Council Canada - National Science Library

    Cabanillas, Miguel; Aneiros, Angel; Monteagudo, Benigno; Santos-García, Diego; Suárez-Amor, Oscar; Ramírez-Santos, Aquilina

    2009-01-01

    ... and urogenital systems. We describe a patient with an extensive epidermal nevus associated with various organ abnormalities, particularly polyostotic fibrous dysplasia, central nervous system lipoma, and aplasia cutis...

  11. Synsedimentary deformation and the paleoseismic record in Marinoan cap carbonate of the southern Amazon Craton, Brazil

    Science.gov (United States)

    Soares, Joelson Lima; Nogueira, Afonso César Rodrigues; Domingos, Fábio; Riccomini, Claudio

    2013-12-01

    Event Layers in Neoproterozoic cap carbonates of Brazil's southwestern Amazon Craton record post-Marinoan synsedimentary seismicity. The 35 m-thick cap carbonates overlie glaciogenic sediments related to the Marinoan glaciation (635 Ma) and are comprised of two units: the lower cap consists of dolomite (˜15 m thick) and the upper cap is limestone (˜25 m thick). The cap dolomite includes pinkish crystalline dolostone with even parallel lamination, stratiform stromatolites, eventual tube structures and megaripple bedded peloidal dolostone interpreted as shallow (euphotic) platform deposits. The cap limestone onlaps the cap dolomite and consists of red marl, gray to black bituminous lime mudstone, bituminous shale with abundant calcite crystal fans (pseudomorphs after aragonite) and even parallel lamination interpreted as moderately deep to deep platform deposits. Five successive events of synsedimentary deformation were recognized in the cap carbonates exposed at Mirassol d'Oeste and Tangará da Serra, in Central Brazil: Event 1 - large to small-scale load cast structures in the contact between dolostones and glaciogenic sediments; Event 2 - stromatolitic lamination truncated by tube structures; Event 3 - vertical to subvertical fractures and faults, and large-scale synclines and anticlines with chevron folds; Event 4 - conglomerate and breccia filling neptunian dykes limited by undeformed beds; and Event 5 - slump and sliding deposits found only in the upper part of the cap limestone. Event 1 was produced by hydroplastic dynamics likely induced by isostatic rebound during ice cap melting in the final stages of the Marinoan glaciation. Events 2 and 5 are autocyclic in nature, and related to depositional processes. Event 2 is linked to fluid and methane escape from organic degradation of microbial mats and domes that formed tubestones; Event 5 is associated to collapse and sliding/slumping in the platform and slope. The reliable orientations of synsedimentary faults

  12. The thickness of glaciers

    Science.gov (United States)

    Faraoni, Valerio; Vokey, Marshall W.

    2015-09-01

    Basic formulae and results of glacier physics appearing in glaciology textbooks can be derived from first principles introduced in algebra-based first year physics courses. We discuss the maximum thickness of alpine glaciers and ice sheets and the relation between maximum thickness and length of an ice sheet. Knowledge of ordinary differential equations allows one to derive also the local ice thickness.

  13. North-south geological differences between the residual polar caps on Mars.

    Science.gov (United States)

    Thomas, P C; Malin, M C; Edgett, K S; Carr, M H; Hartmann, W K; Ingersoll, A P; James, P B; Soderblom, L A; Veverka, J; Sullivan, R

    2000-03-09

    Polar processes can be sensitive indicators of global climate, and the geological features associated with polar ice caps can therefore indicate evolution of climate with time. The polar regions on Mars have distinctive morphologic and climatologic features: thick layered deposits, seasonal CO2 frost caps extending to mid latitudes, and near-polar residual frost deposits that survive the summer. The relationship of the seasonal and residual frost caps to the layered deposits has been poorly constrained, mainly by the limited spatial resolution of the available data. In particular, it has not been known if the residual caps represent simple thin frost cover or substantial geologic features. Here we show that the residual cap on the south pole is a distinct geologic unit with striking collapse and erosional topography; this is very different from the residual cap on the north pole, which grades into the underlying layered materials. These findings indicate that the differences between the caps are substantial (rather than reflecting short-lived differences in frost cover), and so support the idea of long-term asymmetry in the polar climates of Mars.

  14. The influence of capping layers on pore formation in Ge during ion implantation

    Science.gov (United States)

    Alkhaldi, H. S.; Tran, Tuan T.; Kremer, F.; Williams, J. S.

    2016-12-01

    Ion induced porosity in Ge has been investigated with and without a cap layer for two ion species, Ge and Sn, with respect to ion fluence and temperature. Results without a cap are consistent with a previous work in terms of an observed ion fluence and temperature dependence of porosity, but with a clear ion species effect where heavier Sn ions induce porosity at lower temperature (and fluence) than Ge. The effect of a cap layer is to suppress porosity for both Sn and Ge at lower temperatures but in different temperatures and fluence regimes. At room temperature, a cap does not suppress porosity and results in a more organised pore structure under conditions where sputtering of the underlying Ge does not occur. Finally, we observed an interesting effect in which a barrier layer of a-Ge that is denuded of pores formed directly below the cap layer. The thickness of this layer (˜ 8 nm) is largely independent of ion species, fluence, temperature, and cap material, and we suggest that this is due to viscous flow of a-Ge under ion irradiation and wetting of the cap layer to minimize the interfacial free energy.

  15. [Malignant fibrous histiocytoma of the chest wall in a nonagenarian].

    Science.gov (United States)

    Kodama, K; Igase, M; Kazatani, Y; Matsuzaki, K; Murakami, E; Kokubu, T

    1995-01-01

    We report a case of malignant fibrous histiocytoma of the chest wall observed in a 94-year-old woman. She noticed appetite loss and general edema a week before admission. The patient was diagnosed as having congestive heart failure due to valvular heart disease on the basis of echocardiographic findings and became symptom-free by treatment with vasodilators and diuretics. However, chest roentgenogram disclosed a extrapleural mass in the left mid-lateral chest. About 2 months after admission, she experienced left lateral chest pain for the first time. The chest CT scan revealed a 5 x 5 x 2 cm mass, adjacent to the lateral-posterior chest wall and projecting into the thoracic cavity and rib osteolysis. Gallium-67 citrate scintigram showed abnormal isotope accumulation in the left middle chest. Biopsy was not done. The therapeutic approach was mainly pain relief, and no tumor resection, chemotherapy, or radiotherapy was performed. The mass increased in size, and increasingly extended into the thoracic cavity on follow-up CT scans. Furthermore, marked invasion of the tumor to subcutis and subscapula was found. She died of cachexia and respiratory failure 34 weeks after admission. Histologic examination revealed malignant fibrous histiocytoma.

  16. Heat Transfer Modeling for Rigid High-Temperature Fibrous Insulation

    Science.gov (United States)

    Daryabeigi, Kamran; Cunnington, George R.; Knutson, Jeffrey R.

    2012-01-01

    Combined radiation and conduction heat transfer through a high-temperature, high-porosity, rigid multiple-fiber fibrous insulation was modeled using a thermal model previously used to model heat transfer in flexible single-fiber fibrous insulation. The rigid insulation studied was alumina enhanced thermal barrier (AETB) at densities between 130 and 260 kilograms per cubic meter. The model consists of using the diffusion approximation for radiation heat transfer, a semi-empirical solid conduction model, and a standard gas conduction model. The relevant parameters needed for the heat transfer model were estimated from steady-state thermal measurements in nitrogen gas at various temperatures and environmental pressures. The heat transfer modeling methodology was evaluated by comparison with standard thermal conductivity measurements, and steady-state thermal measurements in helium and carbon dioxide gases. The heat transfer model is applicable over the temperature range of 300 to 1360 K, pressure range of 0.133 to 101.3 x 10(exp 3) Pa, and over the insulation density range of 130 to 260 kilograms per cubic meter in various gaseous environments.

  17. Coupled continuum and molecular model of flow through fibrous filter

    Science.gov (United States)

    Zhao, Shunliu; Povitsky, Alex

    2013-11-01

    A coupled approach combining the continuum boundary singularity method (BSM) and the molecular direct simulation Monte Carlo (DSMC) is developed and validated using Taylor-Couette flow and the flow about a single fiber confined between two parallel walls. In the proposed approach, the DSMC is applied to an annular region enclosing the fiber and the BSM is employed in the entire flow domain. The parameters used in the DSMC and the coupling procedure, such as the number of simulated particles, the cell size, and the size of the coupling zone are determined by inspecting the accuracy of pressure drop obtained for the range of Knudsen numbers between zero and unity. The developed approach is used to study flowfield of fibrous filtration flows. It is observed that in the partial-slip flow regime, Kn ⩽ 0.25, the results obtained by the proposed coupled BSM-DSMC method match the solution by BSM combined with the heuristic partial-slip boundary conditions. For transition molecular-to-continuum Knudsen numbers, 0.25 pressure drop and velocity between these two approaches is significant. This difference increases with the Knudsen number that confirms the usefulness of coupled continuum and molecular methods in numerical modeling of transition low Reynolds number flows in fibrous filters.

  18. [Malignant fibrous histiocytoma: pleomorphic sarcoma NOS or pleomorphic fibrosarcoma].

    Science.gov (United States)

    Meister, P

    2005-03-01

    The entity and nosology of pleomorphic malignant fibrous histiocytoma (MFH) is still ambiguous. The actual WHO-Classification uses pleomorphic malignant fibrous histiocytoma (MFH) and pleomorphic sarcoma NOS (not otherwise specified) synonymously. On the other hand text and illustrations convey the impression, that these tumors also could be pleomorphic lipo-, leio- or rhabdomyosarcomas etc. It would have been more informative to emphasize, that with the above mentioned specific sarcoma types MFH-like appearance may occur. Furthermore it would have been more up to date to consider pleomorphic sarcomas NOS as pleomorphic fibrosarcomas and include them in the chapter of fibroblastic and myofibroblastic tumors. This concept already has been carried out for the former myxoid variant of MFH, nowadays preferentially called myxofibrosarcoma. There is controversial discussion about the clinical significance of exact typing of pleomorphic sarcomas. Problems may also occur due to the lack of standards, which degree of desmin expression signifies leiomyosarcoma or just indicates myofibroblasts in MFH. The requirement of exclusion of other tumor-types before diagnosing pleomorphic fibrosarcoma still remains obligatory. After verification of the diagnosis pleomorphic sarcoma NOS or pleomorphic fibrosarcoma, grading e.g. according to criteria of the FFCCS can be carried out. Most cases of pleomorphic fibrosarcoma will qualify as high grade malignant.

  19. Electrospun 3D Fibrous Scaffolds for Chronic Wound Repair

    Directory of Open Access Journals (Sweden)

    Huizhi Chen

    2016-04-01

    Full Text Available Chronic wounds are difficult to heal spontaneously largely due to the corrupted extracellular matrix (ECM where cell ingrowth is obstructed. Thus, the objective of this study was to develop a three-dimensional (3D biodegradable scaffold mimicking native ECM to replace the missing or dysfunctional ECM, which may be an essential strategy for wound healing. The 3D fibrous scaffolds of poly(lactic acid-co-glycolic acid (PLGA were successfully fabricated by liquid-collecting electrospinning, with 5~20 µm interconnected pores. Surface modification with the native ECM component aims at providing biological recognition for cell growth. Human dermal fibroblasts (HDFs successfully infiltrated into scaffolds at a depth of ~1400 µm after seven days of culturing, and showed significant progressive proliferation on scaffolds immobilized with collagen type I. In vivo models showed that chronic wounds treated with scaffolds had a faster healing rate. These results indicate that the 3D fibrous scaffolds may be a potential wound dressing for chronic wound repair.

  20. Electrostatic layer-by-layer construction of fibrous TMV biofilms.

    Science.gov (United States)

    Tiu, Brylee David B; Kernan, Daniel L; Tiu, Sicily B; Wen, Amy M; Zheng, Yi; Pokorski, Jonathan K; Advincula, Rigoberto C; Steinmetz, Nicole F

    2017-01-26

    As nature's choice in designing complex architectures, the bottom-up assembly of nanoscale building blocks offers unique solutions in achieving more complex and smaller morphologies with wide-ranging applications in medicine, energy, and materials science as compared to top-down manufacturing. In this work, we employ charged tobacco mosaic virus (TMV-wt and TMV-lys) nanoparticles in constructing multilayered fibrous networks via electrostatic layer-by-layer (LbL) deposition. In neutral aqueous media, TMV-wt assumes an anionic surface charge. TMV-wt was paired with a genetically engineered TMV-lys variant that displays a corona of lysine side chains on its solvent-exposed surface. The electrostatic interaction between TMV-wt and TMV-lys nanoparticles became the driving force in the highly controlled buildup of the multilayer TMV constructs. Since the resulting morphology closely resembles the 3-dimensional fibrous network of an extracellular matrix (ECM), the capability of the TMV assemblies to support the adhesion of NIH-3T3 fibroblast cells was investigated, demonstrating potential utility in regenerative medicine. Lastly, the layer-by-layer deposition was extended to release the TMV scaffolds as free-standing biomembranes. To demonstrate potential application in drug delivery or vaccine technology, cargo-functionalized TMV biofilms were programmed.

  1. Fibrous Fillers to Manufacture Ultra High Ash/Performance Paper

    Energy Technology Data Exchange (ETDEWEB)

    Dr. VIjay K. Mathur

    2009-04-30

    The paper industry is one of the largest users of energy and emitters of CO2 in the US manufacturing industry. In addition to that, it is facing tremendous financial pressure due to lower cost imports. The fine paper industry has shrunk from 15 million tons per year production to 10 million tons per year in the last 5 years. This has resulted in mill closures and job loses. The AF&PA and the DOE formed a program called Agenda 2020 to help in funding to develop breakthrough technologies to provide help in meeting these challenges. The objectives of this project were to optimize and scale-up Fibrous Fillers technology, ready for commercial deployment and to develop ultra high ash/high performance paper using Fibrous Fillers. The goal was to reduce energy consumption, carbon footprint, and cost of manufacturing paper and related industries. GRI International (GRI) has been able to demonstrate the techno - economic feasibility and economic advantages of using its various products in both handsheets as well as in commercial paper mills. GRI has also been able to develop sophisticated models that demonstrate the effect of combinations of GRI's fillers at multiple filler levels. GRI has also been able to develop, optimize, and successfully scale-up new products for use in commercial paper mills.

  2. Determination of arsenate in water by anion selective membrane electrode using polyurethane–silica gel fibrous anion exchanger composite

    Energy Technology Data Exchange (ETDEWEB)

    Khan, Asif Ali, E-mail: asifkhan42003@yahoo.com; Shaheen, Shakeeba, E-mail: shakeebashaheen@ymail.com

    2014-01-15

    Highlights: • PU–Si gel is new anion exchanger material synthesized and characterized. • This material used as anion exchange membrane is applied for electroanalytical studies. • The method for detection and determination of AsO{sub 4}{sup 3−} in traces amounts discussed. • The results are also verified from arsenic analyzer. -- Abstract: Polyurethane (PU)–silica (Si gel) based fibrous anion exchanger composites were prepared by solid–gel polymerization of polyurethane in the presence of different amounts of silica gel. The formation of PU–Si gel fibrous anion exchanger composite was characterized by Fourier transform infra-red spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA-DTA), scanning electron microscopy (SEM) and elemental analysis. The membrane having a composition of 5:3 (PU:Si gel) shows best results for water content, porosity, thickness and swelling. Our studies show that the present ion selective membrane electrode is selective for arsenic, having detection limit (1 × 10{sup −8} M to 1 × 10{sup −1} M), response time (45 s) and working pH range (5–8). The selectivity coefficient values for interfering ions indicate good selectivity for arsenate (AsO{sub 4}{sup 3−}) over interfering anions. The accuracy of the detection limit results was compared by PCA-Arsenomat.

  3. Determination of arsenate in water by anion selective membrane electrode using polyurethane-silica gel fibrous anion exchanger composite.

    Science.gov (United States)

    Khan, Asif Ali; Shaheen, Shakeeba

    2014-01-15

    Polyurethane (PU)-silica (Si gel) based fibrous anion exchanger composites were prepared by solid-gel polymerization of polyurethane in the presence of different amounts of silica gel. The formation of PU-Si gel fibrous anion exchanger composite was characterized by Fourier transform infra-red spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA-DTA), scanning electron microscopy (SEM) and elemental analysis. The membrane having a composition of 5:3 (PU:Si gel) shows best results for water content, porosity, thickness and swelling. Our studies show that the present ion selective membrane electrode is selective for arsenic, having detection limit (1×10(-8)M to 1×10(-1)M), response time (45s) and working pH range (5-8). The selectivity coefficient values for interfering ions indicate good selectivity for arsenate (AsO4(3-)) over interfering anions. The accuracy of the detection limit results was compared by PCA-Arsenomat.

  4. Anomalous Structure of Palladium-Capped Magnesium Thin Films

    Directory of Open Access Journals (Sweden)

    Kazuki Yoshimura

    2012-07-01

    Full Text Available Pd capped pure Mg thin film (50 nm thick was prepared by magnetron sputtering and its hydrogenation at room temperature has been investigated. After exposure to 4% hydrogen gas diluted by argon, the Pd/Mg thin films show drastic optical changes from the metallic state to the transparent state within five seconds by hydrogenation. Transmission electron microscope observation reveals that this sample has an anomalous structure; Mg grain is surrounded by Pd. This structure may be the reason why Pd/Mg films can be hydrogenated so quickly at room temperature.

  5. Mineral Trioxide Aggregate and Portland Cement for Direct Pulp Capping in Dog: A Histopathological Evaluation

    Directory of Open Access Journals (Sweden)

    Maryam Bidar

    2014-09-01

    Full Text Available Background and aims. Mineral trioxide aggregate and calcium hydroxide are considered the gold standard pulp-capping materials. Recently, Portland cement has been introduced with properties similar to those of mineral trioxide aggregate. His-topathological effects of direct pulp capping using mineral trioxide aggregate and Portland cements on dog dental pulp tis-sue were evaluated in the present study. Materials and methods. This histopatological study was carried out on 64 dog premolars. First, the pulp was exposedwith a sterile bur. Then, the exposed pulp was capped with white or gray mineral trioxide aggregates and white or gray Port-land cements in each quadrant and sealed with glass-ionomer. The specimens were evaluated under a light microscope after 6 months. Statistical analysis was carried out using Kruskal-Wallis test. Statistical significance was defined at α=5%. Results. There was no acute inflammation in any of the specimens. Chronic inflammation in white and gray mineral triox-ide aggregates and white and gray Portland cements was reported to be 45.5%, 27.3%, 57.1% and 34.1%, respectively. Al-though the differences were not statistically significant, severe inflammation was observed mostly adjacent to white mineral trioxide aggregate. The largest extent of increased vascularization (45% and the least increase in fibrous tissue were ob-served adjacent to white mineral trioxide aggregate, with no significant differences. In addition, the least calcified tissue formed adjacent to white mineral trioxide aggregate, although the difference was not significant. Conclusion. The materials used in this study were equally effective as pulp protection materials following direct pulp cap-ping in dog teeth.

  6. High-surface-area silica nanospheres (KCC-1) with a fibrous morphology

    KAUST Repository

    Polshettiwar, Vivek

    2010-08-02

    Fibrous nanosilica: A new family of high-surface-area silica nanospheres (KCC-1) have been prepared (see picture). KCC-1 features excellent physical properties, including high surface area, unprecedented fibrous surface morphology, high thermal (up to 950 °C) and hydrothermal stabilities, and high mechanical stability. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. INFILTRATION KINETICS MODEL OF LIQUID METAL INTO A FIBROUS PREFORM IN CENTRIFUGAL ACCELERATING FIELD

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The infiltration kinetics of the metal melt into a fibrous preform in centrifugal accelerating field is analyzed on the basis of Da rcy's law and the assumption that the fibrous preform is treated as “bundle of capillaries”. The critical rotating speed is analyzed with the established mo del. The influences of the metal melt mass,the rotating speed of the equipmen t,the casting height, the original outer radius of the metal melt and the fibrou s volume fraction in fibrous preform on infilatration are studied. The results show that the critical rotating speed is dependent on critical pressure, castin g height, metal melt mass and the character of fibrous preform. With the incr ease in the metal melt mass, rotating speed of the equipment and original outer radius of the metal melt, or the decrease in casting height and fibrous volume f raction in fibrous of the metal melt,or the decrease in casting height and fibro us volume fraction in fibrous preform,infiltration of metal melt for fibrous pre form becomes easier.

  8. Low level hydrogen peroxide generation from a nonwoven fibrous pectin-cellulose blend

    Science.gov (United States)

    Fibrous pectic-cellulose (FPC) (cellulose blended with primary cell wall pectin at 2 percent by weight of pectin) is product made from naturally occurring plant fibers. FPC is a fibrous mixture of polysaccharides with a low percent by weight of pectin-based primary cell wall and lipid components att...

  9. Evaluation of different measurements for effective thermal conductivity of fibrous materials

    Directory of Open Access Journals (Sweden)

    Tian Ming-Wei

    2014-01-01

    Full Text Available Effective thermal conductivity is generally recognized as the intrinsic factor to reveal the thermal responses of fibrous materials. Here, two typical measurements, the step-wise transient method and the guarded hot plate method, were utilized to identify their feasibility for the effective thermal conductivity of fibrous materials (non-woven fabric and twill fabric with different stacking layers.

  10. Anatomic, histopathologic, and echocardiographic features in a dog with an atypical pulmonary valve stenosis with a fibrous band of tissue and a patent ductus arteriosus.

    Science.gov (United States)

    Yoon, Hakyoung; Kim, Jaehwan; Nahm, Sang-Soep; Eom, Kidong

    2017-07-11

    Congenital pulmonary valve stenosis and patent ductus arteriosus are common congenital heart defects in dogs. However, concurrence of atypical pulmonary valve stenosis and patent ductus arteriosus is uncommon. This report describes the anatomic, histopathologic, and echocardiographic features in a dog with concomitant pulmonary valve stenosis and patent ductus arteriosus with atypical pulmonary valve dysplasia that included a fibrous band of tissue. A 1.5-year-old intact female Chihuahua dog weighing 3.3 kg presented with a continuous grade VI cardiac murmur, poor exercise tolerance, and an intermittent cough. Echocardiography indicated pulmonary valve stenosis, a thickened dysplastic valve without annular hypoplasia, and a type IIA patent ductus arteriosus. The pulmonary valve was thick line-shaped in systole and dome-shaped towards the right ventricular outflow tract in diastole. The dog suffered a fatal cardiac arrest during an attempted balloon pulmonary valvuloplasty. Necropsy revealed pulmonary valve dysplasia, commissural fusion, and incomplete opening and closing of the pulmonary valve because of a fibrous band of tissue causing adhesion between the right ventricular outflow tract and the dysplastic intermediate cusp of the valve. A fibrous band of tissue between the right ventricular outflow track and the pulmonary valve should be considered as a cause of pulmonary valve stenosis. Pulmonary valve stenosis and patent ductus arteriosus can have conflicting effects on diastolic and systolic dysfunction, respectively. Therefore, beta-blockers should always be used carefully, particularly in patients with a heart defect where there is concern about left ventricular systolic function.

  11. FIBROUS DYSPLASIA IN THE MAXILLO-MANDIBULAR REGION – case report

    Directory of Open Access Journals (Sweden)

    Radka Cholakova

    2010-07-01

    Full Text Available Craniofacial fibrous dysplasia is 1 of 3 types of fibrous dysplasia that can affect the bones of the craniofacial complex, including the mandible and maxilla.Fibrous displasia is a skeletal developmental disorder of the bone-forming mesenchyme that manifests as a defect in osteoblastic differentiation and maturation. It is a lesion of unknown etiology, uncertain pathogenesis, and diverse histopathology. Fibrous dysplasia represents about 2, 5% of all bone tumors and over 7% of all benign tumours.The aim of this article is to represent a rare case of bilateral fibrous dysplasia of the upper and lower jaws, in combination with Intellectual disability (previously called mental retardation. The clinical diagnostic approach including imaging studies: Orthopantomogram (OPG and 3D tomography is described. Histological examination was also essential for obtaining a definitive diagnosis.

  12. Fibrous scar in the infrapatellar fat pad after arthroscopy. MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Guangyu; Niitsu, Mamoru; Ikeda, Kotaro; Itai, Yuji [Tsukuba Univ., Ibaraki (Japan). Inst. of Clinical Medicine; Endo, Hideho

    2000-02-01

    We describe the MR appearance of fibrous scars in the infrapatellar fat pad after arthroscopy. The subjects were 96 patients who underwent arthroscope-assisted anterior cruciate ligament (ACL) reconstruction and were examined by oblique sagittal MR imaging at different follow-up intervals. Two observers evaluated the characteristics of the fibrous scars in the infrapatellar fat pad. All fibrous scars with low signal intensity were accentuated at the portal and coursed horizontally through the infrapatellar fat pad. The fibrous scar within the fat pad occurred and peaked within 6 months after arthroscopy. It then subsided gradually and had disappeared by one year later in nearly half of the patients. Identifying MR imaging characteristics of fibrous scars in the fat pad after arthroscopy may be clinically helpful to differentiate these scars from other abnormalities that involve the infrapatellar fat pad. (author)

  13. Fibrous dysplasia of the maxilla: diagnostic reliability of the study image. Literature review.

    Science.gov (United States)

    Fusconi, Massimo; Conte, Michela; Pagliarella, Martina; De Vincentiis, Chiara; De Virgilio, Armando; Benincasa, Anna Teresa; Alessi, Simone; Gallo, Andrea

    2013-12-01

    Objective Fibrous dysplasia (FD) is a benign bone disorder in facial bones. This study evaluates the possibility of diagnosing fibrous dysplasia on imaging alone, without biopsy of the lesion, which is often burdensome for the patient. Materials and Methods The authors bring their experience of four cases of bone lesions of the maxillofacial region and present a review of published studies. The imaging techniques evaluated are computed tomography (CT) and magnetic resonance imaging (MRI) with and without contrast. Results The literature review demonstrates that it is impossible to make diagnosis of fibrous dysplasia exclusively by imaging. Radiographic images often show a ground-glass appearance, which is characteristic but not pathognomonic of fibrous dysplasia. Conclusion Although CT and MRI images may in many cases suggest a diagnosis of fibrous dysplasia, histological examination or follow-up imaging should follow.

  14. ATLAS electromagnetic end-cap detector

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    After the insertion of the first end-cap into this cryostat, the team proceed to the wiring operations. Millions of wires are connected to the electromagnetic calorimeter on this end-cap, whch must be carefully fed out from the detector so that data can be read out. The energy of photons, electrons and positrons will be measured as they pass through the end-cap having been created along the line of the beams in the proton-proton collisions.

  15. Cryopyrin-Associated Autoinflammatory Syndromes (CAPS) - Juvenile

    Science.gov (United States)

    ... Cryopyrin-Associated Autoinflammatory Syndrome (CAPS) (Juvenile) Dermatomyositis (Juvenile) Familial Mediterranean Fever (Juvenile) Fibromyalgia Giant Cell Arteritis Glucocorticoid-induced Osteoperosis ...

  16. Microstructure and properties of nano-fibrous PCL-b-PLLA scaffolds for cartilage tissue engineering

    Directory of Open Access Journals (Sweden)

    L He

    2009-10-01

    Full Text Available Nano-fibrous scaffolds which could potentially mimic the architecture of extracellular matrix (ECM have been considered a good candidate matrix for cell delivery in tissue engineering applications. In the present study, a semicrystalline diblock copolymer, poly(e-caprolactone-block-poly(L-lactide (PCL-b-PLLA, was synthesized and utilized to fabricate nano-fibrous scaffolds via a thermally induced phase separation process. Uniform nano-fibrous networks were created by quenching a PCL-b-PLLA/THF homogenous solution to -20ºC or below, followed by further gelation for 2 hours due to the presence of PLLA and PCL microcrystals. However, knot-like structures as well as continuously smooth pellicles appeared among the nano-fibrous network with increasing gelation temperature. DSC analysis indicated that the crystallization of PCL segments was interrupted by rigid PLLA segments, resulting in an amorphous phase at high gelation temperatures. Combining TIPS (thermally induced phase separation with salt-leaching methods, nano-fibrous architecture and interconnected pore structures (144±36 mm in diameter with a high porosity were created for in vitro culture of chondrocytes. Specific surface area and protein adsorption on the surface of the nano-fibrous scaffold were three times higher than on the surface of the solid-walled scaffold. Chondrocytes cultured on the nano-fibrous scaffold exhibited a spherical condrocyte-like phenotype and secreted more cartilage-like extracellular matrix (ECM than those cultured on the solid-walled scaffold. Moreover, the protein and DNA contents of cells cultured on the nano-fibrous scaffold were 1.2-1.4 times higher than those on the solid-walled scaffold. Higher expression levels of collagen II and aggrecan mRNA were induced on the nano-fibrous scaffold compared to on the solid-walled scaffold. These findings demonstrated that scaffolds with a nano-fibrous architecture could serve as superior scaffolds for cartilage tissue

  17. Axonal regeneration through the fibrous scar in lesioned goldfish spinal cord.

    Science.gov (United States)

    Takeda, A; Atobe, Y; Kadota, T; Goris, R C; Funakoshi, K

    2015-01-22

    Spontaneous nerve regeneration beyond the scar frequently occurs in fish after spinal cord lesions, in contrast to mammals. Here we examined the spatiotemporal relationship between the fibrous scar and axonal regeneration in the goldfish. Within 1 week after hemisection of the spinal cord, the open wound was closed by a fibrous scar that was demarcated from the surrounding nervous tissue by the glia limitans, which was immunoreactive for laminin. Within 1 week after hemisection, regenerating axons entered the fibrous scar, and were surrounded by laminin-coated tubular structures continuous with the glia limitans. Regenerating axons that initially entered the fibrous scar were usually accompanied by glial processes. Within 2-3 weeks after hemisection, the tubular structures became enlarged, and the regenerating axons increased in number, fasciculating in the tubules. Glial processes immunoreactive for glial fibrillary acid protein and 5-hydroxytryptamine neurons then entered the tubular structures to associate with the regenerating axons. The tubular structures developed further, creating tunnels that penetrated the fibrous scar, through which the regenerating axons passed. At 6-12 weeks after hemisection, the fibrous scar was smaller and the enlarged tunnels contained many glial processes and several axons. The findings of present study demonstrated that, following spinal lesions in goldfish, regenerating axons enter and pass the scar tissue. The regenerating axons first enter the fibrous scar with glial elements and then grow through laminin-coated tubular structures within the fibrous scar. Invasion by glial processes and neuronal elements into the tubular structures reduces the fibrous scar area and allows for more regenerating axons to pass beyond the fibrous scar.

  18. Malignant Fibrous Histiocytoma of the Breast: A Case Report

    Directory of Open Access Journals (Sweden)

    Dimosthenis Miliaras

    2012-01-01

    Full Text Available This paper concerns a case of Malignant Fibrous Histiocytoma (MFH of the Breast in a 73-years-old woman. A lump was found in her right breast, measuring 1.7 cm in diameter. Surgical excision followed, and pathology revealed a highly atypical spindle cell tumor. Immunohistochemistry along the histological features, excluded the possibility of carcinoma, malignant phyllodes tumor, or another type of pure sarcoma. There was no history of previous irradiation in the region. MFH is among the rarest types of sarcoma of the breast, and most of the times behaves aggressively. Excision with wide, free-of-tumor margins is the most effective treatment, when feasible.

  19. Determination of physical properties of fibrous thermal insulation

    Directory of Open Access Journals (Sweden)

    Jeandel G.

    2012-10-01

    Full Text Available The objective of this study is to characterize both experimentally and theoretically, conductive and radiative heat transfer within polyester batting. This material is derived from recycled bottles (PET with fibres of constant diameters. Two other mineral and plant fibrous insulation materials, (glass wool and hemp wool are also characterized for comparative purposes. To determine the overall thermophysical properties of the tested materials, heat flux measurement are carried out using a device developed in house. The radiative properties of the material are determined by an inverse method based on measurements of transmittance and reflectance using a FTIR spectrometer and by solving the equation of radiative heat transfer. These measures are compared to results of numerical simulations.

  20. Genetic engineering of fibrous proteins: spider dragline silk and collagen.

    Science.gov (United States)

    Wong Po Foo, Cheryl; Kaplan, David L

    2002-10-18

    Various strategies have been employed to genetically engineer fibrous proteins. Two examples, the subject of this review, include spider dragline silk from Nephila clavipes and collagen. These proteins are highlighted because of their unique mechanical and biological properties related to controlled release, biomaterials and tissue engineering. Cloning and expression of native genes and synthetic artificial variants of the consensus sequence repeats from the native genes has been accomplished. Expression of recombinant silk and collagen proteins has been reported in a variety of host systems, including bacteria, yeast, insect cells, plants and mammalian cells. Future utility for these proteins for biomedical materials is expected to increase as needs expand for designer materials with tailored mechanical properties and biological interactions to elicit specific responses in vitro and in vivo.

  1. Effect of microaerobic fermentation in preprocessing fibrous lignocellulosic materials.

    Science.gov (United States)

    Alattar, Manar Arica; Green, Terrence R; Henry, Jordan; Gulca, Vitalie; Tizazu, Mikias; Bergstrom, Robby; Popa, Radu

    2012-06-01

    Amending soil with organic matter is common in agricultural and logging practices. Such amendments have benefits to soil fertility and crop yields. These benefits may be increased if material is preprocessed before introduction into soil. We analyzed the efficiency of microaerobic fermentation (MF), also referred to as Bokashi, in preprocessing fibrous lignocellulosic (FLC) organic materials using varying produce amendments and leachate treatments. Adding produce amendments increased leachate production and fermentation rates and decreased the biological oxygen demand of the leachate. Continuously draining leachate without returning it to the fermentors led to acidification and decreased concentrations of polysaccharides (PS) in leachates. PS fragmentation and the production of soluble metabolites and gases stabilized in fermentors in about 2-4 weeks. About 2 % of the carbon content was lost as CO(2). PS degradation rates, upon introduction of processed materials into soil, were similar to unfermented FLC. Our results indicate that MF is insufficient for adequate preprocessing of FLC material.

  2. Hyperostotic esthesioneuroblasma: Rare variant and fibrous dysplasia mimicker

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, Manzoor [Neuroradiology Section, Imaging Institute, Cleveland Clinic Foundation, Cleveland (United States); Knott, Phillip Daniel [Director of Facial Plastic and Reconstructive Surgery, Associate Professor of Otolaryngology, UCSF School of Medicine, San Fransisco (United States)

    2014-02-15

    A 65-year-old male presented with a 3-year history of orbital symptoms. An imaging-based diagnosis of fibrous dysplasia involving the skull base was made at another institution. CT showed a diffuse sinonasal mass and ground-glass appearance of the bones of the anterior skull base with bony defects and mucocele formation. MRI demonstrated an accompanying intracranial and orbital rind of soft tissue mass along the hyperostotic bones. FDG-PET showed corresponding intense hypermetabolism. Small cysts were observed at the tumor-brain interface. Biopsy revealed esthesioneuroblastoma with bone infiltration that is compatible with the hyperostotic variant of esthesioneuroblastoma. There are a few cases of hyperostotic esthesioneuroblastoma reported in the literature.

  3. Determination of physical properties of fibrous thermal insulation

    Science.gov (United States)

    Tilioua, A.; Libessart, L.; Joulin, A.; Lassue, S.; Monod, B.; Jeandel, G.

    2012-10-01

    The objective of this study is to characterize both experimentally and theoretically, conductive and radiative heat transfer within polyester batting. This material is derived from recycled bottles (PET) with fibres of constant diameters. Two other mineral and plant fibrous insulation materials, (glass wool and hemp wool) are also characterized for comparative purposes. To determine the overall thermophysical properties of the tested materials, heat flux measurement are carried out using a device developed in house. The radiative properties of the material are determined by an inverse method based on measurements of transmittance and reflectance using a FTIR spectrometer and by solving the equation of radiative heat transfer. These measures are compared to results of numerical simulations.

  4. Focal fibrous overgrowths: a case series and review of literature.

    Science.gov (United States)

    Kolte, Abhay P; Kolte, Rajshri A; Shrirao, Tushar S

    2010-10-01

    Intraoral fibrous overgrowths of the soft tissues are relatively common and may be benign reactive or neoplastic lesions. A series of 10 lesions is presented which included pyogenic granuloma, fibroma and peripheral ossifying fibroma. Almost all the lesions occurred in the second and third decades and were present in the anterior segment of the jaws, with a distinct female predilection. Majority of these lesions were asymptomatic and the patients reported for treatment only due to the discomfort during function. Histopathologic examinations were done for diagnosis of these lesions. Surgical excision along with removal of causative irritants remains the treatment of choice. The extent of excision should depend on the severity of the lesion, as some of these lesions have a tendency for recurrence. All the patients in this series were closely followed up for a period of 2 years and showed no signs of recurrence.

  5. Focal fibrous overgrowths: A case series and review of literature

    Directory of Open Access Journals (Sweden)

    Abhay P Kolte

    2010-01-01

    Full Text Available Intraoral fibrous overgrowths of the soft tissues are relatively common and may be benign reactive or neoplastic lesions. A series of 10 lesions is presented which included pyogenic granuloma, fibroma and peripheral ossifying fibroma. Almost all the lesions occurred in the second and third decades and were present in the anterior segment of the jaws, with a distinct female predilection. Majority of these lesions were asymptomatic and the patients reported for treatment only due to the discomfort during function. Histopathologic examinations were done for diagnosis of these lesions. Surgical excision along with removal of causative irritants remains the treatment of choice. The extent of excision should depend on the severity of the lesion, as some of these lesions have a tendency for recurrence. All the patients in this series were closely followed up for a period of 2 years and showed no signs of recurrence.

  6. Case report 490: Monostotic fibrous dysplasia of the pubis

    Energy Technology Data Exchange (ETDEWEB)

    Buckwalter, J.A.; El-Khoury, G.; Bonfiglio, M.M.; Platz, C.C.

    1988-07-01

    An expansile lesion of the superior pubic ramus in a 32 year old man was discovered incidentally when roentgenograms were obtained to assess the possibility of fracture following an automobile accident. A technetium scan showed increased uptake in the lesion and computed tomography showed expansion of the superior pubic ramus and extension of the lesion from the pubic symphysis to the acetabulum. A needle aspirate of the lesion consisted of blood and giant cells. Based on the appearance of the lesion and the needle aspirate a preliminary diagnosis of giant cell tumor or aneurysmal bone cyst was made. When examined at the time of operation, the lesion was found to be firm and gritty. It was removed and the remaining bone surfaces curetted. Histological examination showed a pattern most consistent with fibrous dysplasia. The pubic ramus healed uneventfully.

  7. Carbon-Based Fibrous EDLC Capacitors and Supercapacitors

    Directory of Open Access Journals (Sweden)

    C. Lekakou

    2011-01-01

    Full Text Available This paper investigates electrochemical double-layer capacitors (EDLCs including two alternative types of carbon-based fibrous electrodes, a carbon fibre woven fabric (CWF and a multiwall carbon nanotube (CNT electrode, as well as hybrid CWF-CNT electrodes. Two types of separator membranes were also considered. An organic gel electrolyte PEO-LiCIO4-EC-THF was used to maintain a high working voltage. The capacitor cells were tested in cyclic voltammetry, charge-discharge, and impedance tests. The best separator was a glass fibre-fine pore filter. The carbon woven fabric electrode and the corresponding supercapacitor exhibited superior performance per unit area, whereas the multiwall carbon nanotube electrode and corresponding supercapacitor demonstrated excellent specific properties. The hybrid CWF-CNT electrodes did not show a combined improved performance due to the lack of carbon nanotube penetration into the carbon fibre fabric.

  8. Malignant fibrous histiocytoma presenting as hemoperitoneum mimicking hepatocellular carcinoma rupture

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Malignant fibrous histiocytoma (MFH) is a pleomorphic mesenchynal sarcoma. It is uncommonly arises primarily from the intra-peritoneal cavity. Primary peritoneal MFH with tumor bleeding and rupture is rare. We describe the imaging features of a 70-year-old patient presenting with ruptured hemorrhagic peritoneal MFH at subhepatic area, accompanied by massive hemoperitoneum,mimicking a ruptured pedunculated hepatocellular carcinoma. Computed tomography (CT) revealed a large heterogeneous enhanced subhepatic mass with adjacent liver, gallbladder and colon invasion. Tumor hemorrhage and rupture complicated with peritoneal seeding and massive bloody ascites were also detected.Angiography showed a hypervascular tumor fed by enlarged right hepatic arteries, cystic artery and omental branches of gastroepiploic artery. The patient underwent laparotomy for tumor resection, but the tumor recurred one month after operation. To our knowledge, the CT appearance of ruptured intraperitoneal MFH complicated by hemoperitoneum has not been previously described.

  9. Solitary fibrous tumor of the pleura: 3 case reports

    Directory of Open Access Journals (Sweden)

    Elias Amorim

    2015-06-01

    Full Text Available Summary Introduction: solitary fibrous tumor of the pleura (SFTP is a rare tumor arising from mesenchymatous cells in submesothelial pleural tissue which, unlike mesothelioma, is not related to asbestos or smoking. Methods: report of four patients who underwent surgical treatment for giant SFTP and review of the pertinent literature. Results: of the four patients operated, two presented symptoms including cough, chest pain and feeling of compression, whereas the other two subjects were asymptomatic. All patients underwent complete surgical resection by wide posterolateral thoracotomy, and surgical specimens removed with minimum bleeding. None of the cases required complementary lobectomy or segmentectomy. All tumors were histologically benign. Conclusion: complete resection of the lesion is the treatment of choice in all SFTP cases. Prognosis of the benign lesion is excellent, although close follow-up is necessary. In the rarer, more aggressive forms, treatment may be complemented by adjunctive chemotherapy or radiotherapy, the benefits of which have yet to be confirmed.

  10. Malignant fibrous histiocytoma of the lower lip: A case report

    Directory of Open Access Journals (Sweden)

    Pechalova Petia F

    2012-03-01

    Full Text Available Malignant fibrous histiocytoma (MFH represents the diagnosis that is still commonly used by both patients and physicians although in 2002., the World Health Organization (WHO declassified MFH as a formal diagnostic entity, renaming it as an undifferentiated pleomorphic sarcoma not specifying it further. MFH is extremely rare in the oral cavity. The aim of this article was to describe a newly diagnosed case of primary MFH in a 78-year-old male presented after 4-months history of rapidly increasing swelling of lower lip. Histopathology of the lesion showed highly malignant cell infiltration with epithelioid/spindle cell type morphology. Immunohistochemical study was positive for vimentin (++, S-100 protein (++ and negative for desmin and cytokeratin. The authors discussed the possibilities of immunohistochemical study and necessity of individual treatment plan in patients with MFH, comparing their point of view with other studies.

  11. Stabilized Lateritic Blocks Reinforced With Fibrous Coir Wastes

    Directory of Open Access Journals (Sweden)

    M G Sreekumar

    2013-11-01

    Full Text Available Tropical countries are rich in lateritic soil, a naturally available raw material for building construction. But its potential in block making is not yet satisfactorily explored. This paper focuses on an experimental investigation for improvising stabilized lateritic blocks (SLB with coir cutting wastes from coir industry as reinforcing elements. Lateritic soil used in this study showed a higher percentage of clay content. Hence it was pre-stabilized with sand and cement. Blocks were prepared by stabilizing it further with waste fibrous additives and tested for strength and durability. Considerable improvement in strength (compressive strength @19% and tensile strength @ 9% and durability characteristics were exhibited by the new fiber reinforced lateritic blocks (FRLB with fiber content of 0.5%. These blocks can be successfully proposed for load bearing construction and as well as for earthquake resistant structures

  12. [Solitary fibrous tumor of the pelvis: a rare extrathoracic manifestation].

    Science.gov (United States)

    Gessmann, J; Seybold, D; Helwing, M; Muhr, G; Schildhauer, T A

    2009-07-01

    Solitary fibrous tumors (SFT) are rare spindle cell neoplasms. To date only very few cases of pelvic SFT have been reported in the literature. SFT are characterized by unique microscopic and immunohistochemical findings. Complete local resection is the treatment of choice. Recurrence and metastasis may be related to infrequent malignant histological features, but histology is not always a reliable predictor for prognosis. Therefore long-term follow-up is necessary.We report about a male patient with a malignant pelvic SFT. After complete resection the tumor recurred after a short period of 6 months posterior to the original location in the pelvis. The differential diagnoses and the therapy options are discussed with a review of the present literature.

  13. A theoretical analysis of local thermal equilibrium in fibrous materials

    Directory of Open Access Journals (Sweden)

    Tian Mingwei

    2015-01-01

    Full Text Available The internal heat exchange between each phase and the Local Thermal Equilibrium (LTE scenarios in multi-phase fibrous materials are considered in this paper. Based on the two-phase heat transfer model, a criterion is proposed to evaluate the LTE condition, using derived characteristic parameters. Furthermore, the LTE situations in isothermal/adiabatic boundary cases with two different heat sources (constant heat flux and constant temperature are assessed as special transient cases to test the proposed criterion system, and the influence of such different cases on their LTE status are elucidated. In addition, it is demonstrated that even the convective boundary problems can be generally estimated using this approach. Finally, effects on LTE of the material properties (thermal conductivity, volumetric heat capacity of each phase, sample porosity and pore hydraulic radius are investigated, illustrated and discussed in our study.

  14. The Surface Groups and Active Site of Fibrous Mineral Materials

    Institute of Scientific and Technical Information of China (English)

    DONG Fa-qin; WAN Pu; FENG Qi-ming; SONG Gong-bao; PENG Tong-jiang; LI Ping; LI Guo-wu

    2004-01-01

    The exposed and transformed groups of fibrous brucite,wollastonite,chrysotile asbestos,sepiolite,palygorskite,clinoptilolite,crocidolite and diatomaceous earth mineral materials are analyzed by IR spectra after acid and alikali etching,strong mechanical and polarity molecular interaction.The results show the active sites concentrate on the ends in stick mineral materials and on the defect or hole edge in pipe mineral materials.The inside active site of mineral materials plays a main role in small molecular substance.The shape of minerals influence their distribution and density of active site.The strong mechanical impulsion and weak chemical force change the active site feature of minerals,the powder process enables minerals exposed more surface group and more combined types.The surface processing with the small polarity molecular or the brand of middle molecular may produce ionation and new coordinate bond,and change the active properties and level of original mineral materials.

  15. Effects of ice-cap unloading on shallow magmatic reservoirs

    Science.gov (United States)

    Bakker, Richard; Frehner, Marcel; Lupi, Matteo

    2015-04-01

    One of the effects of global warming is the increase of volcanic activity. Glacial melting has been shown to cause visco-elastic relaxation of the upper mantle, which in turn promotes upwelling of magmas through the crust. To date, the effects of ice-cap melting on shallow (i.e., less than 10 km depth) plumbing systems of volcanoes are still not clear. We investigate the pressure changes due to glacial unloading around a magmatic reservoir by combining laboratory and numerical methods. As a case study we focus on Snæfellsjökull, a volcano in Western Iceland whose ice cap is currently melting 1.25 meters (thickness) per year. Our approach is as follows: we obtain representative rock samples from the field, preform tri-axial deformation tests at relevant pressure and temperature (PT) conditions and feed the results into a numerical model in which the stress fields before and after ice cap removal are compared. A suite of deformation experiments were conducted using a Paterson-type tri-axial deformation apparatus. All experiments were performed at a constant strain rate of 10-5 s-1, while varying the PT conditions. We applied confining pressures between 50 and 150 MPa and temperatures between 200 and 1000 ° C. Between 200 and 800 ° C we observe a localized deformation and a slight decrease of the Young's modulus from 41 to 38 GPa. Experiments at 900 and 1000 ° C exhibit macroscopically ductile behavior and a marked reduction of the Young's modulus down to 4 GPa at 1000 ° C. These results are used to construct a numerical finite-element model in which we approximate the volcanic edifice and basement by a 2D axisymmetric half-space. We first calculate the steady-state temperature field in the volcanic system and assign the laboratory-derived temperature-dependent Young's modulus to every element of the model. Then the pressure in the edifice is calculated for two scenarios: with and without ice cap. The comparison between the two scenarios allows us estimate the

  16. Landscape Evolution and the Reincarnation of the Residual CO2 Ice Cap of Mars

    Science.gov (United States)

    Byrne, S.; Zuber, M.

    2006-12-01

    Observations of the southern residual CO2 cap of Mars reveal a wide range of landforms including flat-floored quasi-circular pits with steep walls (dubbed Swiss-cheese features). Interannual comparisons show that these depressions are expanding laterally at rates of ~2m/yr to ~4m/yr, prompting suggestions of climate change. The residual CO2 ice cap is up to 10m thick and underlain by an involatile basement, it also contains layers roughly 2m thick representing different accumulation episodes in the recent past. Changes in the appearance of the residual ice between the Mariner 9 and Viking missions indicate that the top-most layer was deposited in that time-frame, soon after the global dust storm of 1971. The spatial density of the Swiss-cheese features, and the rate at which they expand, mean that it is unlikely that any part of the residual ice cap is older than a few centuries. Given this, we may ask: how can there be a residual cap present today for us to observe? To answer this and other questions we have developed a model to examine the evolution of a CO2 ice landscape. This model reproduces the morphologies and expansion rates seen in the actual residual CO2 ice cap. Our model results indicate that the fate of CO2 ice surfaces is controlled by their surface roughness. Surface roughness always increases with time, which results in an unstable situation. When the surface roughness exceeds a critical point small pits can begin to develop. The walls of these pits rapidly steepen and begin retreating which enlarges and deepens the pit. This situation always occurs even if the surface of the CO2 slab has a high enough albedo to have a net mass gain each year. Once these pits begin expanding they quickly erode the entire ice slab. When the underlying non-CO2 material is exposed, it will not frost over again if Mars were to repeat like clockwork every year. We conclude that interannual climatic variability is actually a requirement for the continued existence of a

  17. Non-fibrous inorganic particles in human bronchoalveolar lavage fluids.

    Science.gov (United States)

    Dumortier, P; De Vuyst, P; Yernault, J C

    1989-12-01

    Bronchoalveolar lavage (BAL) is a simple and non-invasive sampling technique of the deep lung. Analytical electron microscopy was used for the identification and quantification of non-fibrous inorganic particles recovered in BAL fluid samples from 51 subjects with various occupational exposures (silica, silicates, metals and alloys, metallic oxides, precious and hard metals, abrasives). Around 4750 particles were analysed. More than sixty different compounds were identified, among which silica, kaolinite, illite, mica, Fe oxides and hydroxides, appeared to be ubiquitous. Feldspar, talc, chlorite, Al oxide, Ti oxide, tungsten carbide, stainless steel, carbonaceous compounds and flyash were also frequently encountered. From 1 to 21 compounds were identified in each sample. Repeated BAL samples obtained for 2 subjects did not show significant differences. Particles characteristic of the occupational exposure were found in BAL up to 21 years after cessation. BAL content can also reflect mixed occupational exposures. Absolute particle concentrations measured in twelve samples ranged between 0.1 and 9.9 x 10(6) particles/ml BAL fluid and mean particle diameter ranged between 0.5 and 1.2 microns. Mineralogical analysis of non-fibrous particles in BAL can be a useful tool to investigate occupational exposures. It allows, in most cases, a better characterization of the exposure than medical questioning. It may be helpful in identifying pathogenic particles, however it must be kept in mind that a positive result is only a proof of exposure and never a proof of disease. The main limitations of this technique are difficulties in sampling severely diseased subjects and inaccuracy in detecting easily soluble compounds and particles with a high rate of alveolar clearance.

  18. The Residual Polar Caps of Mars: Geological Differences and Possible Consequences

    Science.gov (United States)

    Thomas, P. C.; Sullivan, R.; Ingersoll, A. P.; Murray, B. C.; Danielson, G. E.; Herkenhoff, K. E.; Soderblom, L.; Malin, M. C.; Edgett, K. S.; James, P. B.

    2000-01-01

    The Martian polar regions have been known to have thick layered sequences (presumed to consist of silicates and ice), CO2 seasonal frost, and residual frosts that remain through the summer: H2O in the north, largely CO2 in the south. The relationship of the residual frosts to the underlying layered deposits could not be determined from Viking images. The Mars Orbiter Camera on Mars Global Surveyor has provided a 50-fold increase in resolution that shows more differences between the two poles. The north residual cap surface has rough topography of pits, cracks, and knobs, suggestive of ablational forms. This topography is less than a few meters in height, and grades in to surfaces exposing the layers underneath. In contrast, the south residual cap has distinctive collapse and possibly ablational topography emplaced in four or more layers, each approx. two meters thick. The top surface has polygonal depressions suggestive of thermal contraction cracks. The collapse and erosional forms include circular and cycloidal depressions, long sinuous troughs, and nearly parallel sets of troughs. The distinctive topography occurs throughout the residual cap area, but not outside it. Unconformities exposed in polar layers, or other layered materials, do not approximate the topography seen on the south residual cap. The coincidence of a distinct geologic feature, several layers modified by collapse, ablation, and mass movement with the residual cap indicates a distinct composition and/or climate compared to both the remainder of the south polar layered units and those in the north.

  19. Influence of capping layers on CoFeB anisotropy and damping

    Energy Technology Data Exchange (ETDEWEB)

    Natarajarathinam, A. [Center for Materials for Information Technology (MINT Center), University of Alabama, Tuscaloosa, Alabama 35487 (United States); Department of Electrical and Computer Engineering, University of Alabama, Tuscaloosa, Alabama 35487 (United States); Tadisina, Z. R.; Gupta, S. [Center for Materials for Information Technology (MINT Center), University of Alabama, Tuscaloosa, Alabama 35487 (United States); Department of Metallurgical and Materials Engineering, University of Alabama, Tuscaloosa, Alabama 35487 (United States); Mewes, T. [Center for Materials for Information Technology (MINT Center), University of Alabama, Tuscaloosa, Alabama 35487 (United States); Department of Physics and Astronomy, University of Alabama, Tuscaloosa, Alabama 35487 (United States); Watts, S.; Chen, E. [Grandis Inc., Milpitas, California 95035 (United States)

    2012-09-01

    Magnetic behavior of CoFeB at various thicknesses ranging from 2 nm to 8 nm capped with different materials, such as MgO, Ta, Ru, and V have been studied. The films were sputter-deposited and subsequently characterized by magnetometry and broadband ferromagnetic resonance (FMR). There are magnetically dead layers at the interface observed with Ru and Ta capping layers, while MgO and V have almost no effect on the magnetization of the CoFeB. As the ferromagnetic layer is made thinner, the effective magnetization decreases, indicating an interfacial perpendicular anisotropy. Particularly in the case of MgO, V/Ru, and V/Ta capping layers, interfacial perpendicular anisotropy is induced in CoFeB, and the Gilbert damping parameter is also reduced. The origin of this perpendicular magnetic anisotropy (PMA) is understood to be caused by the interface anisotropy between the free layer and the capping layer. The effect of post-deposition annealing and CoFeB thickness on the anisotropy and damping of V/Ta capped samples are reported. Doping CoFeB with vanadium (V) greatly reduced the 4{pi}M{sub s} and 4{pi}M{sub eff} values, resulting in an effective increase in the PMA.

  20. Education and "Thick" Epistemology

    Science.gov (United States)

    Kotzee, Ben

    2011-01-01

    In this essay Ben Kotzee addresses the implications of Bernard Williams's distinction between "thick" and "thin" concepts in ethics for epistemology and for education. Kotzee holds that, as in the case of ethics, one may distinguish between "thick" and "thin" concepts of epistemology and, further, that this distinction points to the importance of…

  1. Thick film hydrogen sensor

    Science.gov (United States)

    Hoffheins, Barbara S.; Lauf, Robert J.

    1995-01-01

    A thick film hydrogen sensor element includes an essentially inert, electrically-insulating substrate having deposited thereon a thick film metallization forming at least two resistors. The metallization is a sintered composition of Pd and a sinterable binder such as glass frit. An essentially inert, electrically insulating, hydrogen impermeable passivation layer covers at least one of the resistors.

  2. Protective capping and surface passivation of III-V nanowires by atomic layer deposition

    Directory of Open Access Journals (Sweden)

    Veer Dhaka

    2016-01-01

    Full Text Available Low temperature (∼200 °C grown atomic layer deposition (ALD films of AlN, TiN, Al2O3, GaN, and TiO2 were tested for protective capping and surface passivation of bottom-up grown III-V (GaAs and InP nanowires (NWs, and top-down fabricated InP nanopillars. For as-grown GaAs NWs, only the AlN material passivated the GaAs surface as measured by photoluminescence (PL at low temperatures (15K, and the best passivation was achieved with a few monolayer thick (2Å film. For InP NWs, the best passivation (∼2x enhancement in room-temperature PL was achieved with a capping of 2nm thick Al2O3. All other ALD capping layers resulted in a de-passivation effect and possible damage to the InP surface. Top-down fabricated InP nanopillars show similar passivation effects as InP NWs. In particular, capping with a 2 nm thick Al2O3 layer increased the carrier decay time from 251 ps (as-etched nanopillars to about 525 ps. Tests after six months ageing reveal that the capped nanostructures retain their optical properties. Overall, capping of GaAs and InP NWs with high-k dielectrics AlN and Al2O3 provides moderate surface passivation as well as long term protection from oxidation and environmental attack.

  3. Protective capping and surface passivation of III-V nanowires by atomic layer deposition

    Energy Technology Data Exchange (ETDEWEB)

    Dhaka, Veer, E-mail: veer.dhaka@aalto.fi; Perros, Alexander; Kakko, Joona-Pekko; Haggren, Tuomas; Lipsanen, Harri [Department of Micro- and Nanosciences, Micronova, Aalto University, P.O. Box 13500, FI-00076 (Finland); Naureen, Shagufta; Shahid, Naeem [Research School of Physics & Engineering, Department of Electronic Materials Engineering, Australian National University, Canberra ACT 2601 (Australia); Jiang, Hua; Kauppinen, Esko [Department of Applied Physics and Nanomicroscopy Center, Aalto University, P.O. Box 15100, FI-00076 (Finland); Srinivasan, Anand [School of Information and Communication Technology, KTH Royal Institute of Technology, Electrum 229, S-164 40 Kista (Sweden)

    2016-01-15

    Low temperature (∼200 °C) grown atomic layer deposition (ALD) films of AlN, TiN, Al{sub 2}O{sub 3}, GaN, and TiO{sub 2} were tested for protective capping and surface passivation of bottom-up grown III-V (GaAs and InP) nanowires (NWs), and top-down fabricated InP nanopillars. For as-grown GaAs NWs, only the AlN material passivated the GaAs surface as measured by photoluminescence (PL) at low temperatures (15K), and the best passivation was achieved with a few monolayer thick (2Å) film. For InP NWs, the best passivation (∼2x enhancement in room-temperature PL) was achieved with a capping of 2nm thick Al{sub 2}O{sub 3}. All other ALD capping layers resulted in a de-passivation effect and possible damage to the InP surface. Top-down fabricated InP nanopillars show similar passivation effects as InP NWs. In particular, capping with a 2 nm thick Al{sub 2}O{sub 3} layer increased the carrier decay time from 251 ps (as-etched nanopillars) to about 525 ps. Tests after six months ageing reveal that the capped nanostructures retain their optical properties. Overall, capping of GaAs and InP NWs with high-k dielectrics AlN and Al{sub 2}O{sub 3} provides moderate surface passivation as well as long term protection from oxidation and environmental attack.

  4. Thermally enhanced perpendicular magnetic anisotropy behaviors of ultrathin [Co/Pd]{sub n} multilayers via NiO{sub x} capping layer

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Woo Seong [Nano Quantum Electronics Lab, Department of Electronics and Computer Engineering, Hanyang University, Seoul 133-791 (Korea, Republic of); Lee, Ja Bin; An, Gwang Guk; Yang, Seung Mo [Novel Functional Materials and Devices Laboratory, Research Institute for Natural Science, Department of Physics, Hanyang University, Seoul 133-791 (Korea, Republic of); Kim, Jae Hong [Division of Nano-Scale Semiconductor Engineering, Hanyang University, Seoul 133-791 (Korea, Republic of); Hong, Jin Pyo, E-mail: jphong@hanyang.ac.kr [Novel Functional Materials and Devices Laboratory, Research Institute for Natural Science, Department of Physics, Hanyang University, Seoul 133-791 (Korea, Republic of); Division of Nano-Scale Semiconductor Engineering, Hanyang University, Seoul 133-791 (Korea, Republic of)

    2015-06-01

    We report the enhanced perpendicular magnetic anisotropy (PMA) features of ultrathin [Co/Pd]{sub 3} multilayers (MLs) employing a NiO{sub x} insertion layer at high annealing temperatures. Thermally enhanced PMA in [Co/Pd]{sub 3}/NiO{sub x} (capping layer) MLs were achieved at a specific capping layer thickness, while no PMA responses were observed for a NiO{sub x} (buffer layer)/[Co/Pd]{sub 3} ML, regardless of NiO{sub x} thickness. X-ray diffraction observations, including rocking curves, identified the relatively different crystalline characteristics of the NiO{sub x} capping and buffer layers. Origin of the enhanced PMAs of [Co/Pd]{sub 3} MLs containing a NiO{sub x} capping layer is described based on the NiO{sub x} capping effect possibly providing additional Co/Oxide i-PMA under high-temperature annealing.

  5. The North Zealand CAP Monitor

    DEFF Research Database (Denmark)

    Nielsen, Minna; Ravn, Pernille; Notander Clausen, Lise

    nurses and two senior doctors. Direct observations of the clinical processes revealed problems of coordination, complex disease trajectories that did not fit with the pneumonia pathway, unclear guidelines and variation in their interpretation. Intervention We designed a measurement system to monitor...... patients with CAP and effects of interventions to improve the quality of their care. Based on current literature we defined and tested a set of indicators and designed an audit form, a database and a dashboard for presenting the results. Two nurses monthly audited randomly selected files of patients...... team of clinicians from the emergency department and inpatient units. Measurement of improvement Audit results are presented as a multidimensional dashboard of aggregated baseline data and run charts to monitor changes. Microbiological tests were delayed, often performed after antibiotics were started...

  6. Assured information flow capping architecture

    Science.gov (United States)

    Black, M. D.; Carvin, N. A.

    1985-05-01

    The Tactical Air Control System (TACS) is that set of Tactical Air Force assets used to assess the air and ground situation, and to plan, allocate, commit, and control assigned resources. Previous studies noted that the TACS elements should be more highly distributed to improve survivability in the battlefield of the future. This document reports on the results of the Assured Information Flow Capping Architecture study, which developed governing concepts for communications architectures that can support the information flow requirements of a future, distributed TACS. Architecture comprising existing and planned communications equipment were postulated and compared with a set of goals to identify deficiencies. Architectures using new equipment that resolve many of the deficiencies were then postulated, and areas needing further investigation were identified.

  7. The Drangajökull ice cap, northwest Iceland, persisted into the early-mid Holocene

    Science.gov (United States)

    Schomacker, Anders; Brynjólfsson, Skafti; Andreassen, Julie M.; Gudmundsdóttir, Esther Ruth; Olsen, Jesper; Odgaard, Bent V.; Håkansson, Lena; Ingólfsson, Ólafur; Larsen, Nicolaj K.

    2016-09-01

    Most glaciers and ice caps in Iceland experienced rapid deglaciation in the early Holocene, reaching a minimum extent during the Holocene Thermal Maximum. Here we present evidence of the Holocene glacial history from lake sediment cores retrieved from seven threshold lakes around the Drangajökull ice cap in the Vestfirðir peninsula, NW Iceland. The sediment cores show on/off signals of glacial meltwater activity, as minerogenic material deposited from glacial meltwater alternates with organic-rich material (gyttja) deposited without glacial meltwater. We base the chronology of the sediment cores on 14C ages and geochemical identification of key tephra layers with known ages. A 25-cm thick layer of the Saksunarvatn tephra in Lake Skorarvatn indicates that the northern part of the ice cap had reached a similar size as today or was smaller already by 10.2 cal kyr BP. However, 14C ages of lake sediment cores from the highlands southeast of Drangajökull suggest that this part of the ice cap was larger than today until 7.8-7.2 cal kyr BP. Even today, the Drangajökull ice cap has a different behavior than the main ice caps in Iceland, characterized by a very low glaciation limit. Because palaeoclimatic proxies show an early-mid Holocene temperature optimum in this part of Iceland, we suggest that the persistence of Drangajökull into the early Holocene and, possibly, also the entire Holocene was due to high winter precipitation.

  8. Nature mangement, landscape and the CAP

    NARCIS (Netherlands)

    Brouwer, F.M.; Godeschalk, F.E.

    2004-01-01

    The integration of nature management, landscape and environmental concerns into the Common Agricultural Policy (CAP) has gained momentum with the CAP reforms adopted in June 2003. The report explores instruments and approaches that contribute to the inte-gration of nature conservation and landscape

  9. ALEPH end-cap and barrel

    CERN Multimedia

    Patrice Loiez

    1993-01-01

    The end-cap is pulled away from the barrel on the ALEPH detector so that the hadronic calorimeter and muon chambers are revealed. The end-cap maximises the data available from particles produced along the direction of the beam. The workers on the inner part of the detector give a sense of scale.

  10. Clay Cap Test Program for the Mixed Waste Management Facility closure at the Savannah River Site

    Energy Technology Data Exchange (ETDEWEB)

    Newell, J.W. (Main (Charles T.), Inc., Charlotte, NC (USA))

    1989-01-01

    A 58 acre low-level radioactive waste disposal facility at the Savannah River Site, a Department of Energy facility near Aiken, South Carolina, requires closure with a RCRA clay cap. A three-foot thick can requiring 300,000 cubic yards of local Tertiary Kaolin clay with an in-situ permeability of less than or equal to 1 {times} 10{sup -7} centimeters per second is to be constructed. The Clay Cap Test Program was conducted to evaluate the source, lab permeability, in-situ permeability, compaction characteristics, representative kaolin clays from the Aiken, SC vicinity. 11 refs., 8 figs., 1 tab.

  11. Creation of Hybrid Nanorods From Sequences of Natural Trimeric Fibrous Proteins Using the Fibritin Trimerization Motif

    Science.gov (United States)

    Papanikolopoulou, Katerina; van Raaij, Mark J.; Mitraki, Anna

    Stable, artificial fibrous proteins that can be functionalized open new avenues in fields such as bionanomaterials design and fiber engineering. An important source of inspiration for the creation of such proteins are natural fibrous proteins such as collagen, elastin, insect silks, and fibers from phages and viruses. The fibrous parts of this last class of proteins usually adopt trimeric, β-stranded structural folds and are appended to globular, receptor-binding domains. It has been recently shown that the globular domains are essential for correct folding and trimerization and can be successfully substituted by a very small (27-amino acid) trimerization motif from phage T4 fibritin. The hybrid proteins are correctly folded nanorods that can withstand extreme conditions. When the fibrous part derives from the adenovirus fiber shaft, different tissue-targeting specificities can be engineered into the hybrid proteins, which therefore can be used as gene therapy vectors. The integration of such stable nanorods in devices is also a big challenge in the field of biomechanical design. The fibritin foldon domain is a versatile trimerization motif and can be combined with a variety of fibrous motifs, such as coiled-coil, collagenous, and triple β-stranded motifs, provided the appropriate linkers are used. The combination of different motifs within the same fibrous molecule to create stable rods with multiple functions can even be envisioned. We provide a comprehensive overview of the experimental procedures used for designing, creating, and characterizing hybrid fibrous nanorods using the fibritin trimerization motif.

  12. Radiographic Differential Diagnosis Between The Fibrous Dysplasia And The Ossifying Fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Karp Shik [Dept. of Dental Radiology, College of Dentistry, Kyungpook National University, Daegu (Korea, Republic of)

    1999-02-15

    The author observed and compared the radiographic features of 49 cases of the fibrous dysplasia and 14 cases of the ossifying fibroma in the osteoblastic or mature stage radiologically and histopathologically. The obtained results were as follows: 1. Fibrous dysplasia occurred most frequently in the 2nd decade, but ossifying fibroma in the 3rd and 4th decades, and both lesions occurred with slight predilection in females. 2. In most cases, chief complaints were painless facial swelling. And 61.1% of fibrous dysplasia occurred in the maxilla, 92.9% of ossifying fibroma in the mandible, and most of these lesions occurred in the premolar-molar region. 3. In the mandibular lesions, ossifying fibroma was shown more oval and round shape, but fibrous dysplasia was shown fusiform shape. 4. Fibrous dysplasia was shown homogeneously distributed, complete radiopaque shadow at 63%, and ossifying fibroma was shown concentric, mixed appearance of radiolucent and radiopaque shadow at 92.9%. 5. Fibrous dysplasia was entirely shown poorly outlined and blended to normal surrounding bone, but ossifying fibroma was shown well-defined border. 6. Cortical thinning and expansion were observed in these lesions, but degree of cortical expansion was more severe in ossifying fibroma than fibrous dysplasia. 7. Loss of lamina dura, tooth displacement, and displacement of mandibular canal were observed in both lesions, but root resorption was observed in ossifying fibroma only.

  13. Fibrous capsule formation of the peritoneal catheter tip in ventriculoperitoneal shunt: Two case reports

    Directory of Open Access Journals (Sweden)

    Tomoaki Kano

    2014-01-01

    Full Text Available Background: A fibrous capsule formation of a peritoneal catheter tip has not previously been researched as a complication of ventriculoperitoneal (VP shunts. Case Description: Two adult patients who had undergone a VP shunt for communicative hydrocephalus following subarachnoid hemorrhage caused by a ruptured aneurysm have been identified with malfunction of the VP shunt system by mild disturbance of consciousness and gait disturbance or loss of appetite. Hydrocephalus was diagnosed by computed tomography and the obstruction of the peritoneal catheter was revealed by shuntgraphy. Laparoscopy was performed and the peritoneal catheter tips were obstructed by fibrous white capsules that covered them. One was a thin membranous capsule like a stocking with two small endoluminal granulomas of the peritoneal catheter, and other one was a fibrous glossy white capsule like a sock. These fibrous capsules were excised by laparoscopy forceps without the conversion to a new peritoneal catheter. Following the procedure, the shunt functioned normally. The pathological diagnoses were peritoneum with foreign body reaction or hyalinization of membranous tissue surrounded by fibrous tissue. Conclusion: These fibrous capsules might be formed by the peritoneal reaction to cerebrospinal fluid as a foreign material. As such, a periodic medical check should be scheduled since a fibrous capsule of the peritoneal catheter tip might be formed again.

  14. Ferromagnetism of polythiophene-capped Au nanoparticles

    Science.gov (United States)

    Suzuki, K.; Zhang, H.; Saito, K.; Garitaonandia, J. S.; Goikolea, E.; Insausti, M.

    2011-04-01

    The magnetic and electrical transport properties of regioregular poly(3-hexylthiophene)-capped Au nanoparticles (NPs) doped with iodine have been investigated to clarify the effectiveness of conductive polymer capping on the induction of ferromagnetism in Au. The room-temperature magnetization curve of the undoped polythiophene-capped Au NPs exhibits a clear hysteresis behavior with a coercive force of 160 Oe. The spontaneous magnetization normalized by the mass of Au is 2.0 × 10-2 emu/g. The spontaneous magnetization was found virtually unaffected by iodine doping, whereas the electrical conductivity is enhanced dramatically to ˜10 S/cm. Our results show that polythiophene capping could lead to spontaneous magnetic polarization in Au NPs, and the conductivity of the polymer capping does not affect the ferromagnetism of the Au nanoparticles, opening a possibility for further investigation into the magnetotransport behavior of ferromagnetic Au NPs.

  15. A large infiltrating fibrous hamartoma of infancy in the abdominal wall with rare associated tuberous sclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Han, Hye-Jeong; Lim, Gye-Yeon [The Catholic University of Korea, Department of Radiology, St. Mary' s Hospital, Seoul (Korea); You, Chang-Young [The Catholic University of Korea, Department of Pathology, St. Mary' s Hospital, Seoul (Korea)

    2009-07-15

    Tuberous sclerosis is a complex autosomal-dominant neurocutaneous syndrome characterized by hamartomatous malformations of fibrous and connective tissues in various organs. Although various histologic types of soft-tissue masses can occur with tuberous sclerosis, we present a unique case of fibrous hamartoma of infancy presenting as large infiltrating cutaneous and subcutaneous masses in the abdominal wall in a 4-year-old boy with tuberous sclerosis. Although the co-occurrence of tuberous sclerosis and fibrous hamartoma of infancy is very rare, it should be considered in the differential diagnosis of subcutaneous soft-tissue masses found in children with tuberous sclerosis. (orig.)

  16. Fibrous Myopathy as a Complication of Repeated Intramuscular Injections for Chronic Headache

    Directory of Open Access Journals (Sweden)

    R Burnham

    2006-01-01

    Full Text Available Two cases of fibrous myopathy associated with repeated, long-term intramuscular injections for treatment of chronic temporomandibular joint pain and chronic headache, respectively, are described. Both patients developed severe, function-limiting contractures in upper and lower extremity muscles used as injection sites. In one of the cases, the contractures were painful. Electrophysiological testing, magnetic resonance imaging and muscle biopsy results were all consistent with myopathy and replacement of skeletal muscle with noncontractile fibrous tissue. These cases are presented to increase awareness of fibrous myopathy and to promote surveillance for this serious potential complication of long-term intramuscular injections in chronic headache and other pain patients.

  17. Case report 557: Solitary intramuscular myxoma in a patient with polyostotic fibrous dysplacia

    Energy Technology Data Exchange (ETDEWEB)

    Glass-Royal, M.C.; Nelson, M.C.; Albert, F.; Lack, E.E.; Bogumill, G.P. (Georgetown Univ., Washington, DC (USA). Medical Center)

    1989-08-01

    We report a case of solitary intramuscular myxoma in a patient with polyostotic fibrous dysplasia and pigmented macules. MR played an important role in the patient's pre-operative evaluation. It has been demonstrated in a review of the literature that a definite relationship exists between myxoma of soft tissues and fibrous dysplasia of the skeleton. Multiple myxomas in a patient with fibrous dysplasia are common and a relationship also exists between myxoma of the soft tissues and the McCune-Albright syndrome. (orig./GDG).

  18. Congenital costo-vertebral fibrous band and congenital kyphoscoliosis: a previously unreported combination.

    Science.gov (United States)

    Eid, Tony; Ghostine, Bachir; Kreichaty, Gaby; Daher, Paul; Ghanem, Ismat

    2013-05-01

    Congenital kyphoscoliosis (CKS) results from abnormal vertebral chondrification. Congenital fibrous bands occur in several locations with variable impact on vertebral development. We report a previously unreported case of a female infant with CKS presenting with an L2 hypoplastic vertebra and a costo-vertebral fibrous band extending to the skin in the form of a dimple. We also describe the therapeutic approach, consisting of surgical excision of the fibrous band and postoperative fulltime bracing, with a 7-year follow-up. We recommend a high index of suspicion in any unusual presentation of CKS and insist on case by case management in such cases.

  19. An ancillary CT finding of intrapulmonary solitary fibrous tumor: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong Jun; Rho, Ji Young; Kwon, Ah Young [CHA Bundang Medical Center, CHA University, Seongnam (Korea, Republic of)

    2017-02-15

    Intrapulmonary solitary fibrous tumor is extremely rare. A few reports have presented typical CT findings such as well-defined, variable—sized, heterogeneously or homogenously well-enhanced intrapulmonary nodules. We report herein a rare case of intrapulmonary solitary fibrous tumor that showed typical clinical and CT features, and we also provide an ancillary CT finding that shows a distinguishable tubular vascular structure within the nodule. The tubular vascular structure was conjoined to the proximal pulmonary vein. In this study, we highlight an ancillary CT finding reported for the first time for the diagnosis of a patient with intrapulmonary solitary fibrous tumor.

  20. Preparation and Properties of Friction Materials by Using Two Kinds of Fibrous Industrial Minerals

    Institute of Scientific and Technical Information of China (English)

    SHEN Shang-yue; HU Shan; LI Zhen; ZHANG De; LIU Xin-hai; SONG Xu-bo

    2003-01-01

    The basic technology and properties of the brake blocks made of modified needle-like wollastonite and fibrous sepiolite were intensively researched.The impact strengthes and fixed velocity friction of the brake blocks prepared by different recipes were tested. The testing results show that it is feasible for needle-like wollastonite and fibrous sepiolite to take the place of asbestos as the reinforced materials of friction materials.The braking effect of the brake blocks is the best when the ratio of the needle-like wollastonite to the fibrous sepiolite was 1∶6.

  1. Fibrous Dysplasia Mimicking Malignancy on 68Ga-DOTATATE PET/CT.

    Science.gov (United States)

    Papadakis, Georgios Z; Millo, Corina; Sadowski, Samira M; Karantanas, Apostolos H; Bagci, Ulas; Patronas, Nicholas J

    2017-03-01

    Fibrous dysplasia of the bone is a developmental benign skeletal disorder characterized by replacement of normal bone and normal bone marrow with abnormal fibro-osseous tissue. We report on a case of a biopsy-proven fibrous dysplasia lesion in the left temporal bone, with intensely increased activity (SUVmax, 56.7) on Ga-DOTATATE PET/CT. The presented data indicate cell surface overexpression of somatostatin receptors by fibrous dysplastic cells and highlight the need of cautious management of Ga-DOTATATE-avid bone lesions, which could mimic malignancy especially in patients with history of neuroendocrine tumors.

  2. A novel route for preparing 5' cap mimics and capped RNAs: phosphate-modified cap analogues obtained via click chemistry.

    Science.gov (United States)

    Walczak, Sylwia; Nowicka, Anna; Kubacka, Dorota; Fac, Kaja; Wanat, Przemyslaw; Mroczek, Seweryn; Kowalska, Joanna; Jemielity, Jacek

    2017-01-01

    The significant biological role of the mRNA 5' cap in translation initiation makes it an interesting subject for chemical modifications aimed at producing useful tools for the selective modulation of intercellular processes and development of novel therapeutic interventions. However, traditional approaches to the chemical synthesis of cap analogues are time-consuming and labour-intensive, which impedes the development of novel compounds and their applications. Here, we explore a different approach for synthesizing 5' cap mimics, making use of click chemistry (CuAAC) to combine two mononucleotide units and yield a novel class of dinucleotide cap analogues containing a triazole ring within the oligophosphate chain. As a result, we synthesized a library of 36 mRNA cap analogues differing in the location of the triazole ring, the polyphosphate chain length, and the type of linkers joining the phosphate and the triazole moieties. After biochemical evaluation, we identified two analogues that, when incorporated into mRNA, produced transcripts translated with efficiency similar to compounds unmodified in the oligophosphate bridge obtained by traditional synthesis. Moreover, we demonstrated that the triazole-modified cap structures can be generated at the RNA 5' end using two alternative capping strategies: either the typical co-transcriptional approach, or a new post-transcriptional approach based on CuAAC. Our findings open new possibilities for developing chemically modified mRNAs for research and therapeutic applications, including RNA-based vaccinations.

  3. FIBROUS MONOLITH WEAR RESISTANT COMPONENTS FOR THE MINING INDUSTRY

    Energy Technology Data Exchange (ETDEWEB)

    Mark J. Rigali

    2001-10-01

    Published mechanical and thermal properties data on a variety of materials was gathered, with focus on materials that have potential with respect to developing wear resistant and damage tolerant composite for mining industry applications. Preliminary core materials of interest include but are not limited to: Diamond, Tungsten Carbide and Cemented Tungsten Carbides, Carbides of Boron, Silicon, Titanium and Aluminum, Diboride of Titanium and Aluminum, Nitrides of Aluminum, Silicon, Titanium, and Boron, Aluminum Oxide, Tungsten, Titanium, Iron, Cobalt and Metal Alloys. Preliminary boundary materials of interest include but are not limited to: W metal, WC-Co, W-Co, WFeNi, and Mo metal and alloys. Several FM test coupons were fabricated with various compositions using the above listed materials. These coupons were consolidated to varying degrees by uniaxial hot pressing, then cut and ground to expose the FM cell structure. One promising system, WC-Co core and WFeNi boundary, was consolidated to 97% of theoretical density, and demonstrates excellent hardness. Data on standard mechanical tests was gathered, and tests will begin on the consolidated test coupons during the upcoming reporting period. The program statements of work for ACR Inc. and its subcontractors, as well as the final contract negotiations, were finalized during the current reporting period. The program start date was February 22nd, 2001. In addition to the current subcontractors, Kennametal Inc., a major manufacturer of cutting tools and wear resistant tooling for the mining industry, expressed considerable interest in ACR's Fibrous Monolith composites for both machine and mining applications. At the request of Kennametal, ARC Inc fabricated and delivered several Fibrous Monolith coupons and components for testing and evaluation in the mining and machine tool applications. Additional samples of Diamond/Tungsten Carbide-6%Cobalt Fibrous Monolith were fabricated and delivered for testing Kennametal

  4. Meurigite, a new fibrous iron phosphate resembling kidwellite

    Science.gov (United States)

    Birch, W.D.; Pring, A.; Self, P.G.; Gibbs, R.B.; Keck, E.; Jensen, M.C.; Foord, E.E.

    1996-01-01

    Meurigite is a new hydrated potassium iron phosphate related to kidwellite and with structural similarities to other late-stage fibrous ferric phosphate species. It has been found at four localities so far - the Santa Rita mine, New Mexico, U.S.A.; the Hagendorf-Sud pegmatite in Bavaria, Germany; granite pegmatite veins at Wycheproof, Victoria. Australia; and at the Gold Quarry Mine, Nevada, U.S.A. The Santa Rita mine is the designated type locality. Meurigite occurs as tabular, elongated crystals forming spherical and hemispherical clusters and drusy coatings. The colour ranges from creamy white to pale yellow and yellowish brown. At the type locality, the hemispheres may reach 2 mm across, but the maximum diameter reached in the other occurrences is usually less than 0.5 mm. A wide variety of secondary phosphate minerals accompanies meurigite at each locality, with dufrenite, cyrilovite. beraunite, rockbridgeite and leucophosphite amongst the most common. Vanadates and uranates occur with meurigite at the Gold Quarry mine. Electron microprobe analysis and separate determination of H2O and CO2 on meurigite from the type locality gave a composition for which several empirical formulae could be calculated. The preferred formula, obtained on the basis of 35 oxygen atoms, is (K0.85Na0.03)??0.88(Fe7.013+Al0.16Cu0.02)??7.19 (PO4)5.11(CO3)0.20(OH) 6.7??7-7.25H2O, which simplifies to KFe73+(PO4)5(OH) 7??8H2O. Qualitative analyses only were obtained for meurigite from the other localities, due to the softness and openness of the aggregates. Because of the fibrous nature of meurigite, it was not possible to determine the crystal structure, hence the exact stoichiometry remains uncertain. The lustre of meurigite varies from vitreous to waxy for the Santa Rita mine mineral, to silky for the more open sprays and internal surfaces elsewhere. The streak is very pale yellow to cream and the estimated Mohs hardness is about 3. Cleavage is perfect on {001] and fragments from the

  5. In vitro biocompatibility of schwann cells on surfaces of biocompatible polymeric electrospun fibrous and solution-cast film scaffolds.

    Science.gov (United States)

    Sangsanoh, Pakakrong; Waleetorncheepsawat, Suchada; Suwantong, Orawan; Wutticharoenmongkol, Patcharaporn; Weeranantanapan, Oratai; Chuenjitbuntaworn, Boontharika; Cheepsunthorn, Poonlarp; Pavasant, Prasit; Supaphol, Pitt

    2007-05-01

    The in vitro responses of Schwann cells (RT4-D6P2T, a schwannoma cell line derived from a chemically induced rat peripheral neurotumor) on various types of electrospun fibrous scaffolds of some commercially available biocompatible and biodegradable polymers, i.e., poly(3-hydroxybutyrate) (PHB), poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), polycaprolactone (PCL), poly(l-lactic acid) (PLLA), and chitosan (CS), were reported in comparison with those of the cells on corresponding solution-cast film scaffolds as well as on a tissue-culture polystyrene plate (TCPS), used as the positive control. At 24 h after cell seeding, the viability of the attached cells on the various substrates could be ranked as follows: PCL film > TCPS > PCL fibrous > PLLA fibrous > PHBV film > CS fibrous approximately CS film approximately PLLA film > PHB film > PHBV fibrous > PHB fibrous. At day 3 of cell culture, the viability of the proliferated cells on the various substrates could be ranked as follows: TCPS > PHBV film > PLLA film > PCL film > PLLA fibrous > PHB film approximately PCL fibrous > CS fibrous > CS film > PHB fibrous > PHBV fibrous. At approximately 8 h after cell seeding, the cells on the flat surfaces of all of the film scaffolds and that of the PCL nanofibrous scaffold appeared in their characteristic spindle shape, while those on the surfaces of the PHB, PHBV, and PLLA macrofibrous scaffolds also appeared in their characteristic spindle shape, but with the cells being able to penetrate to the inner side of the scaffolds.

  6. Ocean Sediment Thickness Contours

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Ocean sediment thickness contours in 200 meter intervals for water depths ranging from 0 - 18,000 meters. These contours were derived from a global sediment...

  7. Origami of thick panels

    Science.gov (United States)

    Chen, Yan; Peng, Rui; You, Zhong

    2015-07-01

    Origami patterns, including the rigid origami patterns in which flat inflexible sheets are joined by creases, are primarily created for zero-thickness sheets. In order to apply them to fold structures such as roofs, solar panels, and space mirrors, for which thickness cannot be disregarded, various methods have been suggested. However, they generally involve adding materials to or offsetting panels away from the idealized sheet without altering the kinematic model used to simulate folding. We develop a comprehensive kinematic synthesis for rigid origami of thick panels that differs from the existing kinematic model but is capable of reproducing motions identical to that of zero-thickness origami. The approach, proven to be effective for typical origami, can be readily applied to fold real engineering structures.

  8. Giant solitary fibrous tumor arising from greater omentum

    Institute of Scientific and Technical Information of China (English)

    Liang Zong; Ping Chen; Guang-Yao Wang; Qun-Shan Zhu

    2012-01-01

    Extrathoracic solitary fibrous tumors (SFTs) have been described at almost every anatomic location of human body,but reports of SFT in the abdominal cavity are rare.We herein present a rare case of SFT originating from greater omentum.Computed tomography revealed a 15.8 cm x 21.0 cm solid mass located at superior aspect of stomach.Open laparotomy confirmed its mesenchymal origin.Microscopically,its tissue was composed of non-organized and spindle-shaped cells exhibiting atypical nuclei,which were divided up by branching vessel and collagen bundles.Immunohistochemical staining showed that this tumor was negative for CD117,CD99,CD68,cytokeratin,calretinin,desmin,epithelial membrane antigen,F8 and S-100,but positive for CD34,bcl-2,α-smooth muscle actin and vimentin.The patient presented no evidence of recurrence during follow-up.SFT arising from abdominal cavity can be diagnosed by histological findings and immunohistochemical markers,especially for CD34 and bcl-2 positive cases.

  9. Fast numerical upscaling of heat equation for fibrous materials

    KAUST Repository

    Iliev, Oleg

    2010-08-01

    We are interested in numerical methods for computing the effective heat conductivities of fibrous insulation materials, such as glass or mineral wool, characterized by low solid volume fractions and high contrasts, i.e., high ratios between the thermal conductivities of the fibers and the surrounding air. We consider a fast numerical method for solving some auxiliary cell problems appearing in this upscaling procedure. The auxiliary problems are boundary value problems of the steady-state heat equation in a representative elementary volume occupied by fibers and air. We make a simplification by replacing these problems with appropriate boundary value problems in the domain occupied by the fibers only. Finally, the obtained problems are further simplified by taking advantage of the slender shape of the fibers and assuming that they form a network. A discretization on the graph defined by the fibers is presented and error estimates are provided. The resulting algorithm is discussed and the accuracy and the performance of the method are illusrated on a number of numerical experiments. © Springer-Verlag 2010.

  10. Fibrous adsorbent for removal of aqueous aromatic hydrocarbons.

    Science.gov (United States)

    Jung, Yong-Jun; Kiso, Yoshiaki; Oguchi, Tatsuo; Yamada, Toshiro; Takagi, Hiroo; Nishimura, Kazuyuki

    2007-01-01

    Bundles of a strongly hydrophobic fibrous material (p-phenylene-2,6-benzobisoxazole; PBO; Zylon) were employed as an adsorbent for the removal of aqueous aromatic compounds, because the PBO fibers are too rigid to be woven and did not entrap suspended solids. The removal performance for nine kinds of polyaromatic hydrocarbons (PAHs) and di-(2-ethylhexyl) phthalate (DEHP) was evaluated. PAHs and DEHP at initial concentrations of 50 microg L(-1) were removed at 72.5-99.9% and ca. 95%, respectively, although the removal efficiencies were affected by the phase ratio (fiber weight/solution volume). The logarithm of the partition coefficient (log K) for planar PAHs was linearly correlated with the logarithm of the n-octanol/water partition coefficient (log P), but nonplanar PAHs, such as cis-stilbene, p-terphenyl, and o-terphenyl, showed significantly lower adsorption performance. The adsorbed PAHs were not desorbed effectively with CH3CN, CH2Cl2, and toluene. On the other hand, DEHP was effectively desorbed with methanol.

  11. Applications of fibrous substrates containing insolubilized phase change polymers

    Science.gov (United States)

    Vigo, Tyrone L.; Bruno, Joseph S.

    1993-01-01

    Incorporation of polyethylene glycols into fibrous substrates produces several improved functional properties when they are insolubilized by crosslinking with a methylolamide resin or by polyacetal formation by their reaction with glyoxal. The range of molecular weights of polyols that may be insolubilized is broad as are the curing conditions (0.25-10 min at 80-200C). Most representative fiber types and blends (natural and synthetic) and all types of fabric constructions (woven, nonwoven and knit) have been modified by incorporation of the bound polyols. The most novel property is the thermal adaptability of the modified substrates to many climatic conditions. This adaptability is due to the high latent heat of the crosslinked polyols that function as phase change materials, the hydrophilic nature of the crosslinked polymer and its enhanced thermal conductivity. Other enhanced properties imparted to fabrics include flex and flat abrasion, antimicrobial activity, reduced static charge, resistance to oily soils, resiliency, wind resistance and reduced lint loss. Applications commercialized in the U.S. and Japan include sportswear and skiwear. Several examples of electric sets of properties useful for specific end uses are given. In addition, other uses are biomedical horticultural, aerospace, indoor insulation, automotive interiors and components and packaging material.

  12. Strength and deformation characteristics of steel fibrous concrete beams

    Institute of Scientific and Technical Information of China (English)

    SINGH Bhupinder; SINGH S.P.; KAUSHIK S.K.

    2007-01-01

    The results of an analytical investigation of the flexural behaviour of Steel Fibre Reinforced Concrete (SFRC) beams are presented. The complete response of the SFRC beams under displacement controlled static loading was obtained using nonlinear Finite Element (FE) techniques implemented with the help ofATENA 2D software. Issues relating to the behaviour of SFRC which have a direct bearing on the FE modelling are discussed with relevance to the software employed for the nonlinear analysis. Constitutive models amenable to numerical analysis for steel fibrous concrete are presented. The structural response throughout the loading regime was captured in terms of the load-deflection behaviour, which in addition to the post-peak response characterized the failure mode of the test beams. The crack patterns at crack initiation and at the end of the tests were also recorded. Experimental results from the specimens of two other investigators were used as control values for this investigation. The response of the specimens of this investigation was evaluated in terms of initial tangent stiffness, peak loads and toughness. Good match was obtained between the results from this investigation and corresponding experimentally obtained values, wherever available.The influence of the fibre content is reflected in the observed trends in peak loads, deflection at peak loads and toughness, which are in broad agreement with known behavioral patterns of SFRC.

  13. De novo malignant solitary fibrous tumor of the kidney

    Directory of Open Access Journals (Sweden)

    Chen Siu-Chung

    2011-10-01

    Full Text Available Abstract The kidney is a relatively infrequent site for solitary fibrous tumor (SFT. Among the previously reported cases, only two cases of malignant renal SFT developing via dedifferentiation from a pre-existing benign SFT have been reported. Here we reported a case of de novo malignant renal SFT clinically diagnosed as renal cell carcinoma in a 50-year-old woman. The tumor was circumscribed but unencapsulated and showed obvious hemorrhagic necrosis. Microscopically, the tumor was composed of patternless sheets of alternating hypercellular and hypocellular areas of spindle cells displaying mild to moderate nuclear atypia, frequent mitoses up to 8 per 10 high power fields, and a 20% Ki-67 proliferative index. Immunohistochemical studies revealed reactivity for CD34, CD99 and vimentin, with no staining for all other markers, confirming the diagnosis of SFT. No areas of dedifferentiation were seen after extensive sampling. Based on the pathologic and immunohistochemical features, a diagnosis of de novo malignant renal SFT was warranted. Our report expands the spectrum of malignant progression in renal SFTs. Even though this patient has been disease-free for 30 months, long-term follow-up is still mandatory.

  14. De novo malignant solitary fibrous tumor of the kidney.

    Science.gov (United States)

    Hsieh, Tsan-Yu; ChangChien, Yi-Che; Chen, Wen-Hsiang; Chen, Siu-Chung; Chang, Liang-Che; Hwang, Cheng-Cheng; Chein, Hui-Ping; Chen, Jim-Ray

    2011-10-05

    The kidney is a relatively infrequent site for solitary fibrous tumor (SFT). Among the previously reported cases, only two cases of malignant renal SFT developing via dedifferentiation from a pre-existing benign SFT have been reported. Here we reported a case of de novo malignant renal SFT clinically diagnosed as renal cell carcinoma in a 50-year-old woman. The tumor was circumscribed but unencapsulated and showed obvious hemorrhagic necrosis. Microscopically, the tumor was composed of patternless sheets of alternating hypercellular and hypocellular areas of spindle cells displaying mild to moderate nuclear atypia, frequent mitoses up to 8 per 10 high power fields, and a 20% Ki-67 proliferative index. Immunohistochemical studies revealed reactivity for CD34, CD99 and vimentin, with no staining for all other markers, confirming the diagnosis of SFT. No areas of dedifferentiation were seen after extensive sampling. Based on the pathologic and immunohistochemical features, a diagnosis of de novo malignant renal SFT was warranted. Our report expands the spectrum of malignant progression in renal SFTs. Even though this patient has been disease-free for 30 months, long-term follow-up is still mandatory.

  15. Fractal Model for Acoustic Absorbing of Porous Fibrous Metal Materials

    Directory of Open Access Journals (Sweden)

    Weihua Chen

    2016-01-01

    Full Text Available To investigate the changing rules between sound absorbing performance and geometrical parameters of porous fibrous metal materials (PFMMs, this paper presents a fractal acoustic model by incorporating the static flow resistivity based on Biot-Allard model. Static flow resistivity is essential for an accurate assessment of the acoustic performance of the PFMM. However, it is quite difficult to evaluate the static flow resistivity from the microstructure of the PFMM because of a large number of disordered pores. In order to overcome this difficulty, we firstly established a static flow resistivity formula for the PFMM based on fractal theory. Secondly, a fractal acoustic model was derived on the basis of the static flow resistivity formula. The sound absorption coefficients calculated by the presented acoustic model were validated by the values of Biot-Allard model and experimental data. Finally, the variation of the surface acoustic impedance, the complex wave number, and the sound absorption coefficient with the fractal dimensions were discussed. The research results can reveal the relationship between sound absorption and geometrical parameters and provide a basis for improving the sound absorption capability of the PFMMs.

  16. [A case of solitary fibrous tumor in the sella turcica].

    Science.gov (United States)

    Shimizu, Kiyoharu; Tominaga, Atsushi; Kinoshita, Yasuyuki; Usui, Satoshi; Sugiyama, Kazuhiko; Kurisu, Kaoru

    2013-10-01

    A 64-year-old male presented with an incidental tumor in the sella turcica during a brain medical checkup. Because he lacked any neurological symptoms or signs of pituitary dysfunction, the patient did not undergo surgery. Three years later, visual disturbances developed, including poor eyesight and visual field defects. The response to the growth hormone(GH)releasing peptide-2 demonstrated severe GH deficiency. MRI revealed an enlarged tumor appearing as a mosaic pattern of high and very low intensity on T2-weighted imaging. The region of very low intensity on T2-weighted imaging exhibited enhancement after T1 gadolinium-DTPA administration. The tumor was totally removed via the microscopic trans-sphenoidal approach in combination with endoscopic observation. The hard tumor adhered to the dura of the sella turcica and the medial wall of the left cavernous sinus. Histological verification confirmed a solitary fibrous tumor(SFT). Fourteen months after the operation, MRI revealed no recurrent tumors. SFT infrequently occurs in the sella turcica; however it should be included in the differential diagnosis in cases of enhanced tumors with marked low intensity on T2-weighted imaging.

  17. A Study of Failure Criteria of Fibrous Composite Materials

    Science.gov (United States)

    Paris, Federico; Jackson, Karen E. (Technical Monitor)

    2001-01-01

    The research described in this paper is focused on two areas: (1) evaluation of existing composite failure criteria in the nonlinear, explicit transient dynamic finite element code, MSC.Dytran, and (2) exploration of the possibilities for modification of material and failure models to account for large deformations, progressive failure, and interaction of damage accumulation with stress/strain response of laminated composites. Following a review of the MSC.Dytran user manual, a bibliographical review of existing failure criteria of composites was performed. The papers considered most interesting for the objective of this report are discussed in section 2. The failure criteria included in the code under consideration are discussed in section 3. A critical summary of the present procedures to perform analysis and design of composites is presented in section 4. A study of the most important historical failure criteria for fibrous composite materials and some of the more recent modifications proposed were studied. The result of this analysis highlighted inadequacies in the existing failure criteria and the need to perform some numerical analyses to elucidate the answer to questions on which some of the proposed criteria are based. A summary of these ideas, which is a proposal of studies to be developed, is presented in section 5. Finally, some ideas for future developments are summarized in section 6.

  18. Properties of nanoparticles affecting simulation of fibrous gas filter performance

    Science.gov (United States)

    Tronville, Paolo; Rivers, Richard

    2015-05-01

    Computational Fluid Dynamics (CFD) codes allow detailed simulation of the flow of gases through fibrous filter media. When the pattern of gas flow between fibers has been established, simulated particles of any desired size can be “injected” into the entering gas stream, and their paths under the influence of aerodynamic drag, Brownian motion and electrostatic forces tracked. Particles either collide with a fiber, or pass through the entire filter medium. They may bounce off the fiber surface, or adhere firmly to the surface or to particles previously captured. Simulated injection of many particles at random locations in the entering stream allows the average probability of capture to be calculated. Many particle properties must be available as parameters for the equations defining the forces on particles in the gas stream, at the moment of contact with a fiber, and after contact. Accurate values for all properties are needed, not only for predicting particle capture in actual service, but also to validate models for media geometries and computational procedures used in CFD. We present a survey of existing literature on the properties influencing nanoparticle dynamics and adhesion.

  19. Shift of the blocking temperature of Co nanoparticles by Cr capping

    Energy Technology Data Exchange (ETDEWEB)

    Ewerlin, Melanie; Demirbas, Derya; Petracic, Oleg [Experimentalphysik IV, Ruhr-Universitaet Bochum, 44780 Bochum (Germany); Agudo, Leonardo; Eggeler, Gunther [Institute for Materials, Department of Materials Science, Ruhr-Universitaet Bochum, 44780 Bochum (Germany)

    2011-07-01

    We have prepared self-assembled Co nanoparticles on Al2O3 buffer layers and studied the effect of capping with various amounts of Cr onto the magnetic properties. Magnetization measurements were performed using superconducting quantum interference device (SQUID) magnetometry and structural characterization using transmission electron microscopy (TEM). The uncapped Co nanoparticles show superparamagnetic behaviour with a blocking temperature of TB=14K. The magnetic properties are strongly influenced by the Cr capping resulting in a decrease of TB for nominal thicknesses of Cr up to 0.15nm. However, for larger values 0.15 nm < tCr <0.4nm the blocking temperature increases again. We suggest that for the first regime the Cr capping layer leads to an enhanced dissipation of magnetization, while the second regime is governed by inter-particle coupling via Cr bridges.

  20. Enhanced Vascularization in Hybrid PCL/Gelatin Fibrous Scaffolds with Sustained Release of VEGF

    National Research Council Canada - National Science Library

    Wang, Kai; Chen, Xuejiao; Pan, Yiwa; Cui, Yun; Zhou, Xin; Kong, Deling; Zhao, Qiang

    2015-01-01

    .... In this study, fibrous scaffolds that consist of PCL and gelatin fibers were fabricated. The gelatin fibers were further functionalized by heparin immobilization, which provides binding sites for VEGF and thus enables the sustained release of VEGF...

  1. Alternating magnetic field heat behaviors of PVDF fibrous mats filled with iron oxide nanoparticles

    Directory of Open Access Journals (Sweden)

    Jinu Kim

    2016-05-01

    Full Text Available To study the magnetic heat behaviors, iron oxide nanoparticles (IONPs and the polyvinylidene fluoride (PVDF fibrous mats filled with IONPs were prepared by using coprecipitaion method and the electrospinning technique. The synthesized IONPs exhibited a magnetization of about 72 emu/g with average diameter of about 10 nm. The magnetizations of PVDF fibrous mats filled with IONPs showed 2.6 emu/g, 5.5 emu/g and 9.9 emu/g for 5 wt.%, 10 wt.% and 20 wt.% IONPs concentration, respectively. The heat of the magnetic fibrous mats were measured under various alternating magnetic fields (90, 128, and 167 Oe, frequencies (190, 250 and 355 kHz. The maximum saturated temperature showed up to 62 °C for 20 wt.% IONPs filled in PVDF fibrous mat under 167 Oe and 355 kHz.

  2. Alternating magnetic field heat behaviors of PVDF fibrous mats filled with iron oxide nanoparticles

    Science.gov (United States)

    Kim, Jinu; Choi, Jung-Su; Yang, Heejae; Ko, Frank K.; Kim, Ki Hyeon

    2016-05-01

    To study the magnetic heat behaviors, iron oxide nanoparticles (IONPs) and the polyvinylidene fluoride (PVDF) fibrous mats filled with IONPs were prepared by using coprecipitaion method and the electrospinning technique. The synthesized IONPs exhibited a magnetization of about 72 emu/g with average diameter of about 10 nm. The magnetizations of PVDF fibrous mats filled with IONPs showed 2.6 emu/g, 5.5 emu/g and 9.9 emu/g for 5 wt.%, 10 wt.% and 20 wt.% IONPs concentration, respectively. The heat of the magnetic fibrous mats were measured under various alternating magnetic fields (90, 128, and 167 Oe), frequencies (190, 250 and 355 kHz). The maximum saturated temperature showed up to 62 °C for 20 wt.% IONPs filled in PVDF fibrous mat under 167 Oe and 355 kHz.

  3. Classical radiological aspects of fibrous dysplasia; Aspectos radiologicos classicos da displasia fibrosa nas radiografias do cranio

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Norma Selma Santos; Moraes e Silva, Denise; Lederman, Henrique M. [Escola Paulista de Medicina, Sao Paulo, SP (Brazil)

    1996-07-01

    The authors, after a review of the literature, show the features of fibrous dysplasia in the skull through conventional radiology, depicting the most common and classics aspects of this disease and its differential diagnosis. (author) 6 refs., 4 figs.

  4. Poliostotic fibrous dysplasia in the left maxilla sinus. Case of presentation

    National Research Council Canada - National Science Library

    Félix Dueñas Ros; Nery María Díaz Yanes; Dianarelys Villafuerte Delgado

    2007-01-01

    .... Paranasal x ray images didn’t permit to make the differential diagnosis between tumor or inflammatory lesions at the beginning, CT scan showed hiperdensy lesions like a tumor that suggest fibrous dysplasia...

  5. Vertical wicking tester for monitoring water transportation behavior in fibrous assembly

    Science.gov (United States)

    Singh, Pratibha; Chatterjee, Arobindo; Ghosh, Subrata

    2016-10-01

    An instrument based on the principle of change of resistance of fibrous assembly on wetting has been developed for precise monitoring of the water transportation behaviour in the fibrous assemblies. The conducting probes sense the change in resistance of a dry fibrous assembly on wetting. This change in resistance generates analog signals which trigger an amplifying circuit. This circuit produces an enlarged copy of the received signals which are further converted to digital signals by a Darlington pair and are encoded to measurable quantity with the help of a microcontroller. The data thus obtained are displayed on a suitable display device. Comparison between conventional strip test and experimental results obtained by the developed instrument shows its reliability. The developed instrument measures the initial rate of water transport with increased precision and hence could be used for detailed study of fluid flow in the fibrous structure.

  6. The pharmaceutical vial capping process: Container closure systems, capping equipment, regulatory framework, and seal quality tests.

    Science.gov (United States)

    Mathaes, Roman; Mahler, Hanns-Christian; Buettiker, Jean-Pierre; Roehl, Holger; Lam, Philippe; Brown, Helen; Luemkemann, Joerg; Adler, Michael; Huwyler, Joerg; Streubel, Alexander; Mohl, Silke

    2016-02-01

    Parenteral drug products are protected by appropriate primary packaging to protect against environmental factors, including potential microbial contamination during shelf life duration. The most commonly used CCS configuration for parenteral drug products is the glass vial, sealed with a rubber stopper and an aluminum crimp cap. In combination with an adequately designed and controlled aseptic fill/finish processes, a well-designed and characterized capping process is indispensable to ensure product quality and integrity and to minimize rejections during the manufacturing process. In this review, the health authority requirements and expectations related to container closure system quality and container closure integrity are summarized. The pharmaceutical vial, the rubber stopper, and the crimp cap are described. Different capping techniques are critically compared: The most common capping equipment with a rotating capping plate produces the lowest amount of particle. The strength and challenges of methods to control the capping process are discussed. The residual seal force method can characterize the capping process independent of the used capping equipment or CCS. We analyze the root causes of several cosmetic defects associated with the vial capping process.

  7. Capping stack: An industry in the making

    Institute of Scientific and Technical Information of China (English)

    Jack Chen; Li Xunke; Xie Wenhui; Kang Yongtian

    2013-01-01

    This paper gives an overview of recent development of the marine well containment system (MWCS)after BP Macondo subsea well blowout occurred on April 20,2010 in the Gulf of Mexico.Capping stack,a hardware utilized to contain blowout well at or near the wellhead is the center piece of MWCS.Accessibility to the dedicated capping stacks is gradually becoming a pre-requirement to obtain the permit for offshore drilling/workover,and the industry for manufacturing,maintenance,transportation and operation of the capping stack is in the making.

  8. Analyses of hydraulic performance of velocity caps

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Degn Eskesen, Mark Chr.; Buhrkall, Jeppe

    2014-01-01

    The hydraulic performance of a velocity cap has been investigated. Velocity caps are often used in connection with offshore intakes. CFD (computational fluid dynamics) examined the flow through the cap openings and further down into the intake pipes. This was combined with dimension analyses...... in order to analyse the effect of different layouts on the flow characteristics. In particular, flow configurations going all the way through the structure were revealed. A couple of suggestions to minimize the risk for flow through have been tested....

  9. Disc-Capped ZnO Nanocombs

    Institute of Scientific and Technical Information of China (English)

    LI Xin; XU chun-xiang; ZHU Guang-Ping; YANG Yi; LIU Jin-Ping; SUN Xiao-Wei; CUI Yi-Ping

    2007-01-01

    Nanocombs with a disc cap structure of ZnO have been synthesized on si substrates by using pure Zinc powders as the source materials based on a vapour-phase transport process.The morphology and the microstructure are investigated by a scanning electron microscopy and x-ray diffraction.Based on the transmission electron microscopy and selected area electron diffraction analysis,the growth directions of three representative parts,nanoribbon stem,nanorod branch and nanodisc cap of the nanocomb are revealed.The growth mechanism of the disc-capped nanocombs is discussed based on the self-catalyzed vapour-liquid-solid process.

  10. Fabrication and characterization of nano-fibrous bilayer composite for skin regeneration application.

    Science.gov (United States)

    Arasteh, Shaghayegh; Kazemnejad, Somaieh; Khanjani, Sayeh; Heidari-Vala, Hamed; Akhondi, Mohammad Mehdi; Mobini, Sahba

    2016-04-15

    Full thickness wound healing with minimal scarring and complete restoration of normal skin properties still remains as a clinical challenge. In this study, a bilayer skin substitute has been fabricated to biomimic the microstructure of natural extracellular matrix of the skin. Human amniotic membrane (HAM) and silk fibroin nano-fibers were combined to produce bilayer construct, which was further treated and characterized. HAM was obtained from healthy mothers and de-epithelized by means of fine enzymatic method to preserve the extracellular structure. Fibroin protein was extracted from fresh Bombyx mori cocoons and transformed to uniform nano-fiberous structure, which was used as a coating layer on the de-epithelized membrane. Surface modification through oxygen plasma treatment was attempted to further induce hydrophilicity. Subsequently, scaffolds were fully characterized in terms of morphology, mechanical properties, hydrophilicity and cell culture response. Histological and immunohistological staining demonstrated localization of fibronectin, cell denudation and structural integrity of HAM after de-epithelization. Scanning electron microscopy images showed bead-free silk fibroin nano-fibers with the average diameter of 250nm. Water contact angle of bilayer scaffolds reduced dramatically to 26.34° after oxygen plasma treatment, which is correlated with more hydrophilic surface. Due to fibroin nano-fiber coating, mechanical properties of HAM improved significantly. Tensile Young's modulus and tensile strength increased from 16.14MPa and 68.46MPa to 25.69MPa and 108.03MPa, respectively. 14days in vitro cultivation of mouse embryonic fibroblasts on the scaffolds revealed that bilayer scaffolds are able to support cell attachment and proliferation. Plasma-etched scaffolds provided the best niche for cell-matrix crosstalk by allowing cells to penetrate beneath the pores and to integrate in fibers direction. The obtained results suggest that the presented nano-fibrous

  11. Study of application of hydrophobic fibrous sorbents for water purification from metal ions

    OpenAIRE

    Е. V. Petrova; Astashkina, А. P.; Filonenko, D. А.; Otmakhov, V. I.; Izaak, Т. I.; Volokitin, G. G.

    2007-01-01

    Sorption properties of hydrophobic fibrous sorbents on the basis of polypropylene and polyethylene terephthalate produced from thermoplastic polymer wastes to metal ion series in aqueous media has been studied. Based on the experimental data of extraction degree dependencies on fibre laying density, dispersity, presence of air in sorbent, volume of pass solution the mechanism of metal ion sorption from aqueous media with hydrophobic fibrous materials is suggested.

  12. Solitary fibrous tumor of the hard palate: a rare entity in oral cavity

    OpenAIRE

    Pinto, Antonione Santos Bezerra; Department of Oral Pathology – São Leopoldo Mandic Institute and Research Center – Campinas – SP – Brazil.; De Araújo, Vera Cavalcanti; Department of Oral Pathology – São Leopoldo Mandic Institute and Research Center – Campinas – SP – Brazil.; Santos, Fabrício Passador; Department of Oral Pathology – São Leopoldo Mandic Institute and Research Center – Campinas – SP – Brazil.; Filho, José Ferreira de Menezes; Antonio Carlos Institute of Tocantins – Araguaína – TO – Brazil.; Siqueira, Viviane; Department of Oral Pathology – São Leopoldo Mandic Institute and Research Center – Campinas – SP – Brazil.; Soares, Andresa Borges; Department of Oral Pathology – São Leopoldo Mandic Institute and Research Center – Campinas – SP – Brazil.

    2016-01-01

    A case of solitary fibrous tumor is reported. Solitary fibrous tumor is a rare neoplasia characterized by the proliferation of fusiform cells of mesenchymal origin accounting for at least 2% of all soft tissue tumors. In this present case, the initial diagnosis was salivary gland tumor because of the location in the hard palate. Histologically, the tumor was composed by conjunctive tissue with proliferation of oval and fusiform cells. The immunohistochemical analysis was positive for CD34 and...

  13. A fibrous hypercrosslinked sorbent prepared on PP-ST-DVB matrix via post-crosslinking reaction

    Institute of Scientific and Technical Information of China (English)

    Feng Liu; Si Guo Yuan; Xiao Li Wang; A.P. Polikarpov; A.A. Shunkevich

    2007-01-01

    A fibrous sorbent possessing abundant micropore structure was firstly prepared via post-crosslinking reaction on the PP-ST-DVB original fiber. Its micromorphology and sorptive properties were investigated, and the results. Demonstrated that the novel fibrous hypercrosslinked sorbent has narrow pore-size distribution, small average porous radius (1.90 nm), high specific surface area (362.31 m2/g), and fine sorptive properties for small organic molecules.

  14. Fibrous Pseudotumor of the Tunica Vaginalis Associated With Hydrocele and Testicular Atrophy

    Directory of Open Access Journals (Sweden)

    Pande Made Wisnu Tirtayasa

    2014-07-01

    Full Text Available Fibrous pseudotumors of the testicular tunics and paratesticular tissue are uncommon lesions. They typically arise as painless scrotal masses that may be associated with hydrocele or history of surgery, trauma, or infection. Although benign, these lesions often clinically indicate malignancy and usually remain undiagnosed preoperatively. Here, we report on a 59-year-old man with fibrous pseudotumor of the tunica vaginalis associated with hydrocele and testicular atrophy.

  15. Poliostotic fibrous dysplasia in the left maxilla sinus. Case of presentation.

    Directory of Open Access Journals (Sweden)

    Félix Dueñas Ros

    2007-04-01

    Full Text Available We present a clinic case of poliostotic fibrous dysplasia in the left maxilla sinus extended to Pterigopaltinar cavity and sphenoid sinus in a 26 year old woman who suffer from facial deformation. Paranasal x ray images didn’t permit to make the differential diagnosis between tumor or inflammatory lesions at the beginning, CT scan showed hiperdensy lesions like a tumor that suggest fibrous dysplasia. The final diagnosis was obtained by biopsy of the lesions.

  16. Cystic solitary fibrous tumor arising from the left occipital meninges: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Bae Geun; Hwang, Yoon Joon; Cha, Soon Joo; Hur, Gham; Kim, Yong Hoon; Kim, Su Young; Seo, Jung Wook; Lee, Ji Young; Kim, Han Seung [Ilsan Paik Hospital, Inje University, School of Medicine, Goyang (Korea, Republic of)

    2007-02-15

    Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm of a spindle-cell origin, and it usually involves the pleura. It's occurrence in various organs of the body has recently been described. Meningeal SFT is very rare. Radiologically, it is a strongly enhancing solid mass and is undistinguishable from fibrous meningioma and hemangiopericytoma. Yet we report here on a case of SFT with massive cystic degeneration that arose from the meninges of the left occipital region.

  17. BMP-2 immobilized PLGA/hydroxyapatite fibrous scaffold via polydopamine stimulates osteoblast growth.

    Science.gov (United States)

    Zhao, Xingyu; Han, Yu; Li, Jiawei; Cai, Bo; Gao, Hang; Feng, Wei; Li, Shuqiang; Liu, Jianguo; Li, Dongsong

    2017-09-01

    Combining biomaterials scaffolds with bone morphogenetic protein-2 (BMP-2) is currently used to promote the regeneration of bone tissue. However, the traditional strategies used to add BMP-2 into the polymer scaffolds directly suffer from limitations that can result in lower growth factor loading and damage the bioactivity of growth factors. In this study, we report the fabrication of poly(lactide-co-glycolide)/hydroxyapatite (PLGA/HA) composite fibrous scaffolds via melt-spinning method to mimic native extracellular matrix (ECM). In order to effectively immobilize BMP-2 on PLGA/HA composite fibrous scaffolds, the surface of the scaffold was modified with polydopamine (PDA) (PDA-PLGA/HA). PDA was chosen as an adhesive polymeric bridge-layer between PLGA/HA fibrous scaffolds and BMP-2. Analysis of the scaffold using scanning electron microscopy, Fourier transform infrared spectroscopy and X-ray photoelectron spectroscope revealed that the PDA coating was attached to the scaffold surface. Moreover, analysis of the scaffold using water contact angle demonstrated an increased hydrophilicity via PDA modification. Furthermore, the PDA coating effectively immobilized BMP-2 on the PDA-PLGA/HA fibrous scaffold and a sustained release profile of BMP-2 was achieved in the BMP-2-immobilized PLGA/HA fibrous scaffold. In vitro experiments showed that BMP-2-immobilized PLGA/HA fibrous scaffold significantly promoted the attachment and proliferation of MC3T3-E1 cells. More importantly, the ALP activity, mRNA expression of osteosis-related genes and calcium deposition in MC3T3-E1 cells cultured on BMP-2-immobilized PLGA/HA fibrous scaffold were significantly increased. These results collectively demonstrate that the BMP-2-immobilized PLGA/HA fibrous scaffold is a promising candidate for bone regeneration. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Circumpolar Active-Layer Permafrost System (CAPS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Circumpolar Active-Layer Permafrost System (CAPS) contains over 100 data sets pertaining to permafrost and frozen ground topics. It also contains detailed...

  19. C-CAP Land Cover, Molokai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  20. Chemical synthesis of dinucleotide cap analogs.

    Science.gov (United States)

    Kore, Anilkumar R; Shanmugasundaram, Muthian

    2014-12-19

    This unit describes a reliable, efficient and general method for the synthesis of standard cap analog (mCAP), m(7)G[5']ppp[5']G, and anti-reverse cap analog (ARCA), m(7,3')(O)G[5']ppp[5']G. The synthesis of required intermediate m(7)GDP or m(2)(7,3'O)GDP has been achieved through regioselective methylation of the corresponding diphosphate using dimethyl sulfate under aqueous conditions. Then, the coupling reaction of m(7)GDP or m(2)(7,3'O)GDP with ImGMP using ZnCl(2)/DMF system affords the corresponding cap analog in good yields. Copyright © 2014 John Wiley & Sons, Inc.

  1. Tip cap for a turbine rotor blade

    Science.gov (United States)

    Kimmel, Keith D

    2014-03-25

    A turbine rotor blade with a spar and shell construction, and a tip cap that includes a row of lugs extending from a bottom side that form dovetail grooves that engage with similar shaped lugs and grooves on a tip end of the spar to secure the tip cap to the spar against radial displacement. The lug on the trailing edge end of the tip cap is aligned perpendicular to a chordwise line of the blade in the trailing edge region in order to minimize stress due to the lugs wanting to bend under high centrifugal loads. A two piece tip cap with lugs at different angles will reduce the bending stress even more.

  2. C-CAP Hawaii 2005 Land Cover

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  3. C-CAP Land Cover, Kauai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  4. C-CAP Land Cover, Maui, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  5. C-CAP Land Cover, Lanai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  6. Cryopyrin-Associated Autoinflammatory Syndromes (CAPS) - Juvenile

    Science.gov (United States)

    ... of the nervous system, including headaches and deafness. CAPS are not contagious. Treatments that block interleukin-1, an important molecule involved in the inflammatory process, are very effective. To prevent permanent damage, treatment ...

  7. C-CAP Land Cover, Niihau, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  8. C-CAP Niihau 2005 Land Cover

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land cover derived from high resolution imagery according to the Coastal Change Analysis Program (C-CAP) protocol. This data set utilized 1...

  9. Truncated Dual-Cap Nucleation Site Development

    Science.gov (United States)

    Matson, Douglas M.; Sander, Paul J.

    2012-01-01

    During heterogeneous nucleation within a metastable mushy-zone, several geometries for nucleation site development must be considered. Traditional spherical dual cap and crevice models are compared to a truncated dual cap to determine the activation energy and critical cluster growth kinetics in ternary Fe-Cr-Ni steel alloys. Results of activation energy results indicate that nucleation is more probable at grain boundaries within the solid than at the solid-liquid interface.

  10. Righting an ATLAS end-cap

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Each component of the giant ATLAS detector must be moved and transported with great caution so that delicate components are not damaged. Therefore, tests are performed, like the one shown. The end-cap weighs 160 tonnes, making the delicate moving process a non-trivial feat. A special crane and supports have been designed so that the end-cap can be raised using a pivot.

  11. Design and implementation of the CAPS receiver

    Science.gov (United States)

    Hu, Yonghui; Hua, Yu; Hou, Lei; Wei, Jingfa; Wu, Jianfeng

    2009-03-01

    In this paper, based on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties, the signal power at the port of the receiver antenna is estimated, and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver. A microstrip receiving antenna is designed with high sensitivity and wide beam orientation, the RF front end of the C/A code and P code receivers, and a processor is designed for the navigation baseband. A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time. A software process flow is provided, and research on relatively key techniques is also conducted, such as signal searching, code loop and carrier loop algorithms, a height assistant algorithm, a dual frequency difference speed measurement technique, a speed measurement technique using a single frequency source with frequency assistance, and a CAPS time correcting algorithm, according to the design frame of the receiver hardware. Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m, height accuracy is 1.2-12.8 m, speed measurement accuracy is 0.13-0.3 m/s, dynamic plane positioning accuracy is 24.4 m, height accuracy is 3.0 m, and speed measurement accuracy is 0.24 m/s. In the case of C/A code, the timing accuracy is 200 ns, and it is also shown that the positioning accuracy of the CAPS precise code receiver (1 σ) is 5 m from south to north, and 0.8 m from east to west. Finally, research on positioning accuracy is also conducted.

  12. Design and implementation of the CAPS receiver

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In this paper, based on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties, the signal power at the port of the receiver antenna is estimated, and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver. A microstrip receiving antenna is designed with high sensitivity and wide beam orientation, the RF front end of the C/A code and P code receivers, and a processor is designed for the navigation baseband. A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time. A software process flow is provided, and research on relatively key techniques is also conducted, such as signal searching, code loop and carrier loop algorithms, a height assistant algorithm, a dual frequency difference speed measurement technique, a speed measurement technique using a single frequency source with frequency assistance, and a CAPS time correcting algorithm, according to the design frame of the receiver hardware. Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m, height accuracy is 1.2-12.8 m, speed measurement accuracy is 0.13-0.3 m/s, dynamic plane positioning accuracy is 24.4 m, height accuracy is 3.0 m, and speed measurement accuracy is 0.24 m/s. In the case of C/A code, the timing accuracy is 200 ns, and it is also shown that the positioning accuracy of the CAPS precise code receiver (1σ ) is 5 m from south to north, and 0.8 m from east to west. Finally, research on positioning accuracy is also conducted.

  13. Cap-assisted colonoscopy and detection of Adenomatous Polyps (CAP) study: a randomized trial.

    Science.gov (United States)

    Pohl, Heiko; Bensen, Steve P; Toor, Arifa; Gordon, Stuart R; Levy, L Campbell; Berk, Brian; Anderson, Peter B; Anderson, Joseph C; Rothstein, Richard I; MacKenzie, Todd A; Robertson, Douglas J

    2015-10-01

    Cap-assisted colonoscopy has improved adenoma detection in some but not other studies. Most previous studies have been limited by small sample sizes and few participating endoscopists. The aim of the current study was to evaluate whether cap-assisted colonoscopy improves adenoma detection in a two-center, multi-endoscopist, randomized trial. Consecutive patients who presented for an elective colonoscopy were randomized to cap-assisted colonoscopy (4-mm cap) or standard colonoscopy performed by one of 10 experienced endoscopists. Primary outcome measures were mean number of adenomas per patient and adenoma detection rate (ADR). Secondary outcomes included procedural measures and endoscopist variation; a logistic regression model was employed to examine predictors of increased detection with cap use. A total of 1113 patients (64 % male, mean age 62 years) were randomized to cap-assisted (n = 561) or standard (n = 552) colonoscopy. The mean number of adenomas detected per patient in the cap-assisted and standard groups was similar (0.89 vs. 0.82; P = 0.432), as was the ADR (42 % vs. 40 %; P = 0.452). Cap-assisted colonoscopy achieved a faster cecal intubation time (4.9 vs. 5.8 minutes; P Cap-assisted colonoscopy resulted in a 20 % increase in ADR for some endoscopists and in a 15 % decrease for others. Individual preference for the cap was an independent predictor of increased adenoma detection in adjusted analysis (P cap-assisted colonoscopy, adenoma detection was not. Cap-assisted colonoscopy may be beneficial for selected endoscopists. clinicalTrials.gov (NCT01935180). © Georg Thieme Verlag KG Stuttgart · New York.

  14. Effects of Ru and Ag cap layers on microstructure and magnetic properties of FePt ultrathin films.

    Science.gov (United States)

    Liu, Mingfeng; Jin, Tianli; Hao, Liang; Cao, Jiangwei; Wang, Ying; Wu, Dongping; Bai, Jianmin; Wei, Fulin

    2015-01-01

    The effects of Ru and Ag cap layers on the microstructure and magnetic properties of the FePt ultrathin films have been investigated. The results indicate that i) The Ag cap layer segregates from the FePt/Ag bilayer, lowers the FePt ordering temperature, promotes the FePt thin films to form island structure, and enhances the coercivity; ii) The Ru cap layer increases the FePt ordering temperature, helps to maintain smooth continuous structure film, and restrains the FePt (001) orientation and perpendicular magnetic anisotropy (PMA). The effects become more pronounced for the 3-nm-thick FePt thin films. The effects can be mainly attributed to the different melting point and thermal expansion stress between the cap layer and FePt thin films.

  15. Effects of Ru and Ag cap layers on microstructure and magnetic properties of FePt ultrathin films

    Science.gov (United States)

    Liu, Mingfeng; Jin, Tianli; Hao, Liang; Cao, Jiangwei; Wang, Ying; Wu, Dongping; Bai, Jianmin; Wei, Fulin

    2015-04-01

    The effects of Ru and Ag cap layers on the microstructure and magnetic properties of the FePt ultrathin films have been investigated. The results indicate that i) The Ag cap layer segregates from the FePt/Ag bilayer, lowers the FePt ordering temperature, promotes the FePt thin films to form island structure, and enhances the coercivity; ii) The Ru cap layer increases the FePt ordering temperature, helps to maintain smooth continuous structure film, and restrains the FePt (001) orientation and perpendicular magnetic anisotropy (PMA). The effects become more pronounced for the 3-nm-thick FePt thin films. The effects can be mainly attributed to the different melting point and thermal expansion stress between the cap layer and FePt thin films.

  16. [Investigation of fibrous cultural materials by infrared spectroscopy].

    Science.gov (United States)

    Luo, Xi-yun; Du, Yi-ping; Shen, Mei-hua; Zhang, Wen-qing; Zhou, Xin-guang; Fang, Shu-ying; Zhang, Xuan

    2015-01-01

    Cultural fibrous material includes both important categories, i. e. textile and paper, consisting of precious cultural materials in museum, such as costume, painting, and manuscript. In recent years more and more connoisseur and conservator's concerns are, through nondestructive method, the authenticity and the ageing identification of these cultural relics especially made from fragile materials. In this research, we used attenuated total reflection infrared spectroscopy to identify five traditional textile fibers, alongside cotton, linen, wool, mulberry silk and tussah silk, and another five paper fibers alongside straw, wheat straw, long qisong, Chinese alpine rush and mulberry bar, which are commonly used for making Chinese traditional xuan paper. The research result showed that the animal fiber (wool, mulberry silk and tussah silk) and plant fiber (cotton and linen) were easier to be distinguished by comparing the peaks at 3 280 cm-1 belonging to NH stretching vibration and a serious peaks related to amide I to amide III. In the spectrum of wool, the peak at 1 076 cm-1 was assigned to the S-O stretching vibration absorption of cystine in wool structure and can be used to tell wool from silk. The spectrum of mulberry silk and tussah silk seems somewhat difficult to be identified, as well as the spectrum of cotton and linen. Five rural paper fibers all have obvious characteristic peaks at 3 330, 2 900 cm-1 which are related to OH and CH stretching vibration. In the fingerprint wavenumber range of 1 600 - 800 cm, the similar peaks also appeared at 1 370, 1 320 cm-1 and 1 162, 1 050 cm-1, both group peaks respectively are related to CH and CO vibration in the structure of cellulose and hemicellulose in paper fibers. Although there is more similarity of the infrared spectroscopy of these 5 paper fibers, some tiny difference in absorbance also can be found at 3 300 cm-1 and in the fingerprint range at 1 332, 1 203, and 1 050 cm-1 which are related to C-O-C vibration

  17. Novel Oscillation Period of the Interlayer Exchange Coupling in Fe/Cr/Fe Due to MgO Capping

    Science.gov (United States)

    Halley, D.; Bengone, O.; Boukari, S.; Weber, W.

    2009-01-01

    A novel period of the interlayer exchange coupling as a function of Cr thickness is observed in epitaxial Fe/Cr/Fe (001) sandwiches capped with MgO. This additional period, equal to 3 chromium atomic layers, vanishes when the capping is Cr. A strong oscillation of the magnetic coupling is also observed as a function of the thickness of the Fe layer next to the MgO capping layer. This effect is attributed to the formation of quantum well states in this Fe layer. It is believed that this confinement modifies the reflection coefficient at the Cr/Fe interface for electrons of a particular symmetry and leads to the new coupling period which is linked to the Fermi surface topology of chromium.

  18. Analytical and experimental studies of wakes behind circularly capped bubbles

    Science.gov (United States)

    Bessler, W. F.

    The wakes behind circularly capped bubbles are examined by means of an experimental and analytical study. A single two-inch diameter bubble is injected into a six by three foot fluid column, one half inch thick, producing an essentially two-dimensional flow. Aspirin powder placed in the fluid column just prior to bubble release highlights the structure of the flow field before dissolving. High speed film and sequenced photographs are taken to document the observed results. Pressure-time measurements are made with sensitive capacitive transducers mounted in the rear column wall and are synchronized with photographs using a high speed clock. Experimental fluids, prepared by mixing water and glycerine in varying proportions, are used to study the effects of viscosity on bubble shape and wake structure. Testing is performed over a range of Reynolds numbers from 14 to 29,655 which includes the transition from circularly capped to ellipsoidal bubble shape. Experimental data is reduced and summarized in convenient dimensionless form to permit comparison with analytical predictions.

  19. Suspended hybrid films assembled from thiol-capped gold nanoparticles.

    Science.gov (United States)

    Zhang, Yu Xin; Huang, Ming; Hao, Xiao Dong; Dong, Meng; Li, Xin Lu; Huang, Jia Mu

    2012-01-01

    In this work, we explored the formation processes of suspended hybrid thin films of thiol-capped Au nanoparticles (AuNPs) inside metal oxide tubular structures. We found that a balance between in-film interactions of the AuNPs and boundary interactions with metal oxides is a key in making these special organic-inorganic thin films. The hybrid films process many processing advantages and flexibilities, such as controllable film thickness, interfacial shape and inter-AuNPs distance, tuning of particle sizes, thiol population, chain lengths, and other new properties by introducing functional groups to thiol chains. Among their many unique features, the assembly-disassembly property may be useful for future on-off or store-release applications.

  20. Borel-Moore homology and cap product operations

    OpenAIRE

    Hanamura, Masaki

    2016-01-01

    We show that, for a simplicial complex, the supported cap product operation on Borel-Moore homology coincides with the supported cap product on simplicial homology. For this purpose we introduce the supported cap product for locally finite singular homology, and compare the cap product on the three homology theories.

  1. 42 CFR 418.309 - Hospice cap amount.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Hospice cap amount. 418.309 Section 418.309 Public...) MEDICARE PROGRAM HOSPICE CARE Payment for Hospice Care § 418.309 Hospice cap amount. The hospice cap amount is calculated using the following procedures: (a) The cap amount is $6,500 per year and is adjusted...

  2. Anti-pp,. cap alpha cap alpha. and p. cap alpha. elastic scattering at high energies and Chou-Yang conjecture

    Energy Technology Data Exchange (ETDEWEB)

    Saleem, M.; Fazal-e-Aleem; Rifique, M.

    1987-03-01

    The recent experimental measurements for anti-pp and ..cap alpha cap alpha.. elastic scattering at high energies have shown that the Chou-Yang conjecture regarding the relationship between the electromagnetic and the hadronic form factor of a particle is only an approximation. A new ansatz has been proposed to obtain hadronic form factors of proton and the ..cap alpha..-particle. These form factors have been used to explain the various characteristics of anti-pp, ..cap alpha cap alpha.. and p..cap alpha.. elastic scattering at high energies.

  3. Compositional variation of fibrous callus and joint cartilage in different internal environments

    Institute of Scientific and Technical Information of China (English)

    SUN Xiao-tang; HU Yun-yu; ZHAO Li; L(U) Rong; WANG Jun; BAI Jian-ping

    2006-01-01

    Objective: To evaluate the compositional variation of fibrous callus in the fracture site and the joint cavity and joint cartilage after being transplanted in the muscle pouch.Methods: Thirty 2-month-old New Zealand white rabbits (weighing 1-1.5 kg) were randomly divided into two groups: a callus transplantation group (Group A, n =15) and a cartilage transplantation group ( Group B, n =15). In Group A, closed radius fracture was made and the autologous fibrous callus was transplanted in the right knee joint cavity at 12 days postoperatively. In Group B, the right knee joint cartilage of the animals was transplanted in the autologous back muscle pouches under anesthesia. Then all the animals were killed by overdose anesthetic 3 weeks after transplantation. And the transplanted fibrous callus,the healed bones in the fracture sites and the transplanted joint cartilage were obtained for assessment of compositional variation.Results: Pure fibrous composition was found in the callus at the fracture sites in Group A at 12 days postoperatively. And for 11 out of the 15 animals, the fibrous callus was transformed into cartilaginous tissues after 3 weeks of transplantation, but the fibrous callus was absent in the other 4 animals. The fibrous calluses at the original site and the fracture locus were differentiated into bony tissues. Bony tissue transformation was found in the transplanted joint cartilages in the muscle pouch of all the animals in Group B.Conclusions: The fracture sites or joint cavity may facilitate callus differentiation in different ways: the former is helpful for osteogenesis while the latter for the development and maintenance of cartilages, and the muscle pouch is inclined to induce the osteogenic phenotype for cartilages.

  4. Highly Sensitive Aluminum-Based Biosensors using Tailorable Fano Resonances in Capped Nanostructures

    Science.gov (United States)

    Lee, Kuang-Li; Hsu, Hsuan-Yeh; You, Meng-Lin; Chang, Chia-Chun; Pan, Ming-Yang; Shi, Xu; Ueno, Kosei; Misawa, Hiroaki; Wei, Pei-Kuen

    2017-03-01

    Metallic nanostructure-based surface plasmon sensors are capable of real-time, label-free, and multiplexed detections for chemical and biomedical applications. Recently, the studies of aluminum-based biosensors have attracted a large attention because aluminum is a more cost-effective metal and relatively stable. However, the intrinsic properties of aluminum, having a large imaginary part of the dielectric function and a longer evanescent length, limit its sensing capability. Here we show that capped aluminum nanoslits fabricated on plastic films using hot embossing lithography can provide tailorable Fano resonances. Changing height of nanostructures and deposited metal film thickness modulated the transmission spectrum, which varied from Wood’s anomaly-dominant resonance, asymmetric Fano profile to surface plasmon-dominant resonance. For biolayer detections, the maximum surface sensitivity occurred at the dip of asymmetric Fano profile. The optimal Fano factor was close to ‑1.3. The wavelength and intensity sensitivities for surface thickness were up to 2.58 nm/nm and 90%/nm, respectively. The limit of detection (LOD) of thickness reached 0.018 nm. We attributed the enhanced surface sensitivity for capped aluminum nanoslits to a reduced evanescent length and sharp slope of the asymmetric Fano profile. The protein-protein interaction experiments verified the high sensitivity of capped nanostructures. The LOD was down to 236 fg/mL.

  5. Noble metal capping effects on the spin-reorientation transitions of Co/Ru(0001)

    Energy Technology Data Exchange (ETDEWEB)

    El Gabaly, Farid; Figuera, Juan de la [Centro de Microanalisis de Materiales, Universidad Autonoma de Madrid, Madrid 28049 (Spain); McCarty, Kevin F [Sandia National Laboratories, Livermore, CA 94550 (United States); Schmid, Andreas K [Lawrence Berkeley National Laboratory, Berkeley 94720 (United States); Munoz, M Carmen; Gallego, Silvia [Instituto de Ciencia de Materiales de Madrid, CSIC, Madrid 28049 (Spain); Szunyogh, Laszlo [Department of Theoretical Physics, Institute of Physics, Budapest University of Technology and Economics, H-111 Budapest (Hungary); Weinberger, Peter [Center for Computational Nanoscience, A-1010 Wien (Austria)], E-mail: juan.delafiguera@iqfr.csic.es

    2008-07-15

    Thin films of Co/Ru(0001) are known to exhibit an unusual spin reorientation transition (SRT) coupled to the completion of Co atomic layers for Co thicknesses under four layers. By means of spin-polarized low-energy electron microscopy, we follow in real space the magnetization orientation during the growth of atomically thick capping layers on Co/Ru(0001). Capping with noble metal (Cu, Ag and Au) elements modifies the SRT depending on the Co and overlayer thickness and on the overlayer material, resulting in an expanded range of structures with high perpendicular magnetic anisotropy. The origin of the SRT can be explained in terms of ab initio calculations of the layer-resolved contributions to the magnetic anisotropy energy. Besides the changes in the SRT introduced by the capping, a quantitative enhancement of the magnetic anisotropy is identified. A detailed analysis of the interplay between strain and purely electronic effects allows us to identify the conditions that lead to a high perpendicular magnetic anisotropy in thin hcp Co films.

  6. Oscillatory magnetic anisotropy and spin-reorientation induced by heavy-metal cap in Cu/FeCo/M (M =Hf or Ta): A first-principles study

    Science.gov (United States)

    Ong, P. V.; Kioussis, Nicholas; Amiri, P. Khalili; Wang, K. L.

    2016-11-01

    Using ab initio electronic structure calculations we have investigated the effect of the thickness of a heavy-metal (HM) cap on the magnetic anisotropy of the Cu /FeCo /HM (n ) thin film where HM = Hf and Ta with thicknesses of n =0 -10 monolayers (MLs). We find that the Hf cap results in a large perpendicular magnetic anisotropy (PMA), which exhibits quasiperiodic oscillation with a period of two MLs. In contrast, the Ta-capped heterostructure exhibits a spin reorientation from out-of-plane to in-plane magnetization orientation at two MLs of Ta. Moreover, the MA remains negative and depends weakly on the Ta-cap thickness beyond the critical thickness. The underlying mechanism of the PMA oscillation is the periodic change in spin-flip spin-orbit coupling between the minority-spin Fe d (x z ,y z ) and majority Fe d (z2) at Γ ¯, which is induced by the hybridization with Hf at the FeCo/Hf interface. Our results help resolve the contradictory experiments regarding the role of the FeCo/Ta interface on the PMA of the MgO/FeCo/Ta junction. The calculations reveal that the ferromagnet/Hf is promising for spintronic applications and that the capping material and thickness are additional parameters for optimizing the functional properties of spintronic devices.

  7. 75 FR 49527 - Caps Visual Communications, LLC; Black Dot Group; Formerly Known as Caps Group Acquisition, LLC...

    Science.gov (United States)

    2010-08-13

    ... Employment and Training Administration Caps Visual Communications, LLC; Black Dot Group; Formerly Known as... Adjustment Assistance on June 24, 2010, applicable to workers of Caps Visual Communications, LLC, Black Dot..., Caps Visual Communications, LLC, Black Dot Group, formerly known as Caps Group Acquisition,...

  8. Scenarios for a cap beyond 2013; Implications for EU27 agriculture and the cap budget

    NARCIS (Netherlands)

    Helming, J.F.M.; Terluin, I.J.

    2011-01-01

    An ex ante analysis of a set of five policy components (proposed post 2013 CAP measures) has been carried out for the 2014-2020 period, based on the EC Communication The CAP towards 2020 of 18 November 2010. The policy components are defined in such a way that they focus on the contribution of farme

  9. Storage of cellular 5' mRNA caps in P bodies for viral cap-snatching.

    Science.gov (United States)

    Mir, M A; Duran, W A; Hjelle, B L; Ye, C; Panganiban, A T

    2008-12-09

    The minus strand and ambisense segmented RNA viruses include multiple important human pathogens and are divided into three families, the Orthomyxoviridae, the Bunyaviridae, and the Arenaviridae. These viruses all initiate viral transcription through the process of "cap-snatching," which involves the acquisition of capped 5' oligonucleotides from cellular mRNA. Hantaviruses are emerging pathogenic viruses of the Bunyaviridae family that replicate in the cytoplasm of infected cells. Cellular mRNAs can be actively translated in polysomes or physically sequestered in cytoplasmic processing bodies (P bodies) where they are degraded or stored for subsequent translation. Here we show that the hantavirus nucleocapsid protein binds with high affinity to the 5' cap of cellular mRNAs, protecting the 5' cap from degradation. We also show that the hantavirus nucleocapsid protein accumulates in P bodies, where it sequesters protected 5' caps. P bodies then serve as a pool of primers during the initiation of viral mRNA synthesis by the viral polymerase. We propose that minus strand segmented viruses replicating in the cytoplasm have co-opted the normal degradation machinery of P bodies for storage of cellular caps. Our data also indicate that modification of the cap-snatching model is warranted to include a role for the nucleocapsid protein in cap acquisition and storage.

  10. Self-assembly studies of native and recombinant fibrous proteins

    Science.gov (United States)

    Wilson, Donna Lucille

    The structure of silk proteins consists of alternating amorphous (glycine-rich) and ordered crystalline regions (poly(alanine) and poly(glycine-alanine) repeats), where the organized regions are typically beta-sheet assemblies. In collagen, the basic helical repeat (glycine-proline-hydroxyproline and variants on this repeat) drives hierarchical assembly. Three polypeptide chains form left-handed poly-proline II-like helices, these three chains then self-assemble to form a right-handed triple helix. The focus of this thesis is on these proteins and defined variations thereof to reveal features of fibrous protein self-assembly. The amino acid sequences of native silk and collagen and their respective assembly environments have been systematically manipulated. Spider silk protein, based on the consensus sequence of Nephila clavipes dragline-silk, was genetically engineered to include methionines flanking the beta-sheet forming polyalanine regions. These methionines could be selectively oxidized and reduced, altering the bulkiness and charge of a methionine-based sulfoxide group to control beta-sheet formation by steric hindrance. A second version of the sterical trigger included a recognition site for Protein Kinase A allowing for the selective phosphorylation of a serine. Patterning a monolayer of precursor "director" molecules on length scales ranging from nanometer- to micrometer-length scales simplifies the interpretation of supramolecular assembly. Utilizing the atomic force microscopy (AFM)-based technique of dip-pen nanolithography, thiolated collagen and a collagen-like peptide were patterned at 30--50 nm line widths on evaporated gold surfaces. These are the largest molecules thus far positively printed on a surface at such small-length scales. The method preserved the triple helical structure and biological activity of collagen and even fostered the formation of characteristic higher-levels of structural organization. Nanopatterns were also achieved for

  11. Optical reflectance in fibrous tissues and skeletal muscles

    Science.gov (United States)

    Ranasinghesagara, Janaka C.

    We studied two biological tissues with optically anisotropic structures: high moisture soy protein extrudates and skeletal muscles. High moisture extrusion has been used to produce vegetable meat analogs that resemble real animal meat and have significant health benefits. Since visual and textural properties are key factors for consumer acceptance, assessing fiber formation in the extruded soy protein product is important for quality control purpose. A non-destructive method based on photon migration was developed to measure fiber formation in extruded soy proteins. The measured fiber formation index in intact samples showed good agreement with that obtained from image analysis on peeled samples. By implementing this new method in a fast laser scanning system, we have acquired two dimensional mappings of fiber formation and orientation in the entire sample in real time. In addition to fibrous structures, skeletal muscles have a unique periodic sarcomere structure which produces strong light diffractions. However, inconsistent experimental results have been reported in single fiber diffraction studies. By applying the three-dimensional coupled wave theory in a physical sarcomere model, we found that a variety of experimental observations can be explained if inhomogeneous muscle morphological profiles are considered. We also discovered that the sarcomere structure produced a unique optical reflectance pattern in whole muscle. None of the existing light propagation theories are able to describe this pattern. We developed a Monte Carlo model incorporating the sarcomere diffraction effect. The simulated results quantitatively resemble the unique patterns observed in experiments. We used a set of parameters to quantify the optical reflectance profiles produced by a point incident light in whole muscle. Two parameters, q and B, were obtained by numerically fitting the equi-intensity contours of the reflectance pattern. Two spatial gradients were calculated along the

  12. Preparation of poly(ethylene glycol/polylactide hybrid fibrous scaffolds for bone tissue engineering

    Directory of Open Access Journals (Sweden)

    Ni P

    2011-11-01

    Full Text Available PeiYan Ni, ShaoZhi Fu, Min Fan, Gang Guo, Shuai Shi, JinRong Peng, Feng Luo, ZhiYong QianState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of ChinaAbstract: Polylactide (PLA electrospun fibers have been reported as a scaffold for bone tissue engineering application, however, the great hydrophobicity limits its broad application. In this study, the hybrid amphiphilic poly(ethylene glycol (PEG/hydrophobic PLA fibrous scaffolds exhibited improved morphology with regular and continuous fibers compared to corresponding blank PLA fiber mats. The prepared PEG/PLA fibrous scaffolds favored mesenchymal stem cell (MSC attachment and proliferation by providing an interconnected porous extracellular environment. Meanwhile, MSCs can penetrate into the fibrous scaffold through the interstitial pores and integrate well with the surrounding fibers, which is very important for favorable application in tissue engineering. More importantly, the electrospun hybrid PEG/PLA fibrous scaffolds can enhance MSCs to differentiate into bone-associated cells by comprehensively evaluating the representative markers of the osteogenic procedure with messenger ribonucleic acid quantitation and protein analysis. MSCs on the PEG/PLA fibrous scaffolds presented better differentiation potential with higher messenger ribonucleic acid expression of the earliest osteogenic marker Cbfa-1 and mid-stage osteogenic marker Col I. The significantly higher alkaline phosphatase activity of the PEG/PLA fibrous scaffolds indicated that these can enhance the differentiation of MSCs into osteoblast-like cells. Furthermore, the higher messenger ribonucleic acid level of the late osteogenic differentiation markers OCN (osteocalcin and OPN (osteopontin, accompanied by the positive Alizarin red S staining, showed better maturation of osteogenic induction on the PEG/PLA fibrous scaffolds at the

  13. Martian north polar cap summer water cycle

    CERN Document Server

    Brown, Adrian J; Becerra, Patricio; Byrne, Shane

    2016-01-01

    A key outstanding question in Martian science is 'are the polar caps gaining or losing mass and what are the implications for past, current and future climate?' To address this question, we use observations from the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) of the north polar cap during late summer for multiple Martian years, to monitor the summertime water cycle in order to place quantitative limits on the amount of water ice deposited and sublimed in late summer. We establish here for the first time the summer cycle of water ice absorption band signatures on the north polar cap. We show that in a key region in the interior of the north polar cap, the absorption band depths grow until Ls=120, when they begin to shrink, until they are obscured at the end of summer by the north polar hood. This behavior is transferable over the entire north polar cap, where in late summer regions 'flip' from being net sublimating into net condensation mode. This transition or 'mode flip' happens earlier for ...

  14. Analysis on the positioning precision of CAPS

    Institute of Scientific and Technical Information of China (English)

    JI YuanFa; SUN XiYan

    2009-01-01

    As a newly developed satellite positioning system,the Chinese Area Positioning System (CAPS) Is a typical direct sequence spread spectrum ranging system like GPS.The positioning precision of such navigation signals depends on many factors,including the pseudo-code rate,the signal to noise ratio,the processing methods for tracking loops and so on.This paper describes the CAPS link budget,the solution approach for CAPS positioning,focusing on the autocorrelation function feature of C/A code signals.The CAPS signal measurement precision is studied by the software approach together with theoretical analysis of the range resolution.Because the conventional Delay Lock Loop (DLL) is vulnerable to the impact of noise,a narrow correlator and multiple correlatore as well as the corresponding discrimination methods of phases are proposed,which improves the robustness of DLL and the code-phase resolution of the measurement.The results show that the Improvement of the DLL structure and the discrimination method are the most important way to improve the ranging resolution.Theoretical analysis and experimental results show that a CAPS receiver could reach a 20-m positioning precision by using three satellites with a supported height from an altimeter.

  15. Analysis on the positioning precision of CAPS

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    As a newly developed satellite positioning system, the Chinese Area Positioning System (CAPS) is a typical direct sequence spread spectrum ranging system like GPS. The positioning precision of such navigation signals depends on many factors, including the pseudo-code rate, the signal to noise ratio, the processing methods for tracking loops and so on. This paper describes the CAPS link budget, the solution approach for CAPS positioning, focusing on the autocorrelation function feature of C/A code signals. The CAPS signal measurement precision is studied by the software approach together with theoretical analysis of the range resolution. Because the conventional Delay Lock Loop (DLL) is vul- nerable to the impact of noise, a narrow correlator and multiple correlators as well as the corresponding discrimination methods of phases are proposed, which improves the robustness of DLL and the code-phase resolution of the measurement. The results show that the improvement of the DLL structure and the discrimination method are the most important way to improve the ranging resolution. Theoretical analysis and experimental results show that a CAPS receiver could reach a 20-m positioning precision by using three satellites with a supported height from an altimeter.

  16. Contrasting the morphology, anatomy and fungal colonization of new pioneer and fibrous roots.

    Science.gov (United States)

    Zadworny, Marcin; Eissenstat, David M

    2011-04-01

    Not all roots born as first-order branches are the same and this has important consequences for overall function. We hypothesized that, compared with fibrous roots, pioneer roots are built to live longer at the expense of absorptive capacity. We tested this hypothesis by investigating pioneer and fibrous roots in their first 14 d of life in the arbuscular mycorrhizal tree species: Acer negundo, Acer saccharum, Juglans nigra, Liriodendron tulipifera and Populus tremuloides. Root observations were made with root-access boxes that allowed roots to be sampled at known ages in field-grown trees. Compared to fibrous roots, pioneer roots had larger diameter, lower specific root length, greater average length and a lack of mycorrhizal or nonmycorrhizal fungal colonization. Pioneer roots < 14 d old had more layers of hypodermis with a lower percentage of putative passage cells and more protoxylem groups than similar age fibrous roots. Our results suggest that pioneer roots are constructed for defense against biotic and abiotic challenges, exploration of soil distal to the stem, high fibrous root branching and secondary development with high axial hydraulic conductivity at the expense of mycorrhizal colonization and high absorptive capacity for water and nutrients.

  17. IL-4 gene expression in adventitial layer (fibrous layer) of hepatic ovine and bovine hydatid cysts.

    Science.gov (United States)

    Dorosti, Zahra; Tolouei, Sepideh; Khanahmad, Hossein; Jafari, Rasool; Jafaee, Fereshteh; Sharafi, Seyedeh Marayam; Darani, Hossein Yousofi

    2016-09-01

    Cystic Echinococcosis is a parasitic disease with cosmopolitan distribution caused by the tape worm Echinococcus granulosus. Fibrous layer is developed around the cyst as a host immune response reaction. The aim of this study was to evaluate the rate of IL-4 gene expression in fibrous layer of bovine and ovine hepatic hydatid cysts using quantitative technique of Real-Time PCR. In this descriptive study the samples of hydatid cyst fibrous layer were taken from 6 bovine and 6 ovine hepatic hydatid cysts. Samples of normal liver tissue close to the cyst were also taken as controls. Total RNA from each sample was extracted and then converted to cDNA. Afterward, the rate of IL-4 gene expression for each sample was evaluated using real-time PCR technique. Data were analyzed by REST software (version 2.0.13, 2009). In sheep the rate of IL-4 gene expression in the fibrous layer of hepatic hydatid cysts was 1.98 times more than the rate of IL4 gene expression in control samples, but the difference was not significant (P = 0.561). In cattle the rate of IL-4 gene expression in the fibrous layer of hepatic hydatid cysts was 9.84 times more than that of control samples which was statistically significant (P layer of bovine hydatid cyst, it can be concluded that this interleukin may play an important role in host parasite relationship.

  18. Histochemical and immunohistochemical differences between solitary oral fibroma and fibrous papule of the face*

    Science.gov (United States)

    Henriques, Águida Cristina Gomes; Freitas, Roseana de Almeida; Pires, Bruno Cunha; Gurgel, Clarissa Araújo; dos Santos, Jean Nunes

    2016-01-01

    Background The morphological similarities between fibrous papules of the face and multiple sporadic oral fibromas were mentioned long ago and a relationship between them has been reported in the literature. Objective The aim of this study was to evaluate the participation of mast cells, elastin and collagen in a series of oral fibromas and fibrous papules of the face in order to better understand the possible role of these factors in fibrosis and the formation of these lesions. Methods Thirty cases of oral fibroma involving the buccal mucosa and 30 cases of fibrous papules of the face were selected. Tissue samples were submitted to picrosirius red staining and immunohistochemistry using anti-elastin and anti-tryptase antibodies. Results The percentage of tryptase-positive mast cells and expression of elastin were higher in cases of fibrous papules of the face (p < 0.05). In contrast, a higher intensity of collagen deposition was observed in oral fibromas. The results showed mast cell accumulation and higher elastin synthesis in fibrous papules of the face, and mast cell accumulation with higher collagen fiber synthesis in oral fibromas. Conclusion These findings support the hypothesis that mast cells influence the development and growth of these lesions through different mechanisms. PMID:27828630

  19. A dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytes.

    Science.gov (United States)

    Chua, Kian-Ngiap; Tang, Yen-Ni; Quek, Chai-Hoon; Ramakrishna, Seeram; Leong, Kam W; Mao, Hai-Quan

    2007-09-01

    We have designed a novel dual-functional electrospun fibrous scaffold comprising two fiber mesh layers that were modified differently to induce two separate biological responses from hepatocytes. The first fiber layer was galactosylated on the surface to mediate hepatocyte attachment, while the second layer was loaded with 3-methylcholanthrene (3-Mc) to enhance cytochrome P450 activity of hepatocytes. Primary rat hepatocytes cultured on the galactosylated fibrous scaffolds loaded with different concentrations of 3-Mc were compared for their cell attachment efficiency, albumin secretion activity and cytochrome P450-dependent 7-ethoxycoumarin O-deethylase activity. This hybrid fibrous scaffold mediated hepatocyte attachment with slightly lower efficiency (76+/-2.3%) than a single-layer galactosylated fibrous scaffold (84+/-3.5%). More importantly, the cytochrome P450 activity of the hepatocytes cultured on the hybrid scaffold correlated well with the 3-Mc loading level. The results also showed that transfer of 3-Mc to hepatocytes through direct cell-fiber contact was the dominant transport route, with the induced cytochrome P450 activity being 1.9- to 4.8-fold higher than that of transfer of 3-Mc to hepatocytes via dissolution from fibers to medium. This study demonstrates the feasibility of creating multi-functional fibrous scaffolds that serve both as an adhesive substrate and as a delivery vehicle for bioactive molecules.

  20. Hypertrophied anal papillae and fibrous anal polyps, should they be removed during anal fissure surgery?

    Institute of Scientific and Technical Information of China (English)

    Pravin J. Gupta

    2004-01-01

    AIM: Hypertrophied anal papillae and fibrous anal polyps are not given due importance in the proctology practice.They are mostly ignored being considered as normal structures. The present study was aimed to demonstrate that hypertrophied anal papillae and fibrous anal polyps could cause symptoms to the patients and that they should be removed in treatment of patients with chronic fissure in anus.METHODS: Two groups of patients were studied. A hundred patients were studied in group A in which the associated fibrous polyp or papillae were removed by radio frequency surgical device after a lateral subcutaneous sphincterotomy for relieving the sphincter spasm. Another group of a hundred patients who also had papillae or fibrous polyps, were treated by lateral sphincterotomy alone. They were followed up for one year.RESULTS: Eighty-nine percent patients from group A expressed their satisfaction with the treatment in comparison to only 64% from group B who underwent sphincterotomy alone with the papillae or anal polyps left untreated. Group A patients showed a marked reduction with regard to pain and irritation during defecation (P= 0.0011),pricking or foreign body sensation in the anus (P = 0.0006)and pruritus or wetness around the anal verge (P = 0.0008).CONCLUSION: Hypertrophied anal papillae and fibrous anal polyps should be removed during treatment of chronic anal fissure. This would add to effectiveness and completeness of the procedure.

  1. Catastrophic antiphospholipid syndrome (CAPS): Descriptive analysis of 500 patients from the International CAPS Registry.

    Science.gov (United States)

    Rodríguez-Pintó, Ignasi; Moitinho, Marta; Santacreu, Irene; Shoenfeld, Yehuda; Erkan, Doruk; Espinosa, Gerard; Cervera, Ricard

    2016-12-01

    To analyze the clinical and immunologic manifestations of patients with catastrophic antiphospholipid syndrome (CAPS) from the "CAPS Registry". The demographic, clinical and serological features of 500 patients included in the website-based "CAPS Registry" were analyzed. Frequency distribution and measures of central tendency were used to describe the cohort. Comparison between groups regarding qualitative variables was undertaken by chi-square or Fisher exact test while T-test for independent variables was used to compare groups regarding continuous variables. 500 patients (female: 343 [69%]; mean age 38±17) accounting for 522 episodes of CAPS were included in the analysis. Forty percent of patients had an associated autoimmune disease, mainly systemic lupus erythematosus (SLE) (75%). The majority of CAPS episodes were triggered by a precipitating factor (65%), mostly infections (49%). Clinically, CAPS was characterized by several organ involvement affecting kidneys (73%), lungs (60%), brain (56%), heart (50%), and skin (47%). Lupus anticoagulant, IgG anticardiolipin and IgG anti-β2-glycprotein antibodies were the most often implicated antiphospholipid antibodies (83%, 81% and 78% respectively). Mortality accounted for 37% of episodes of CAPS. Several clinical differences could be observed based on the age of presentation and its association to SLE. Those cases triggered by a malignancy tended to occur in older patients, while CAPS episodes in young patients were associated with an infectious trigger and peripheral vessels involvement. Additionally, CAPS associated with SLE were more likely to have severe cardiac and brain involvement leading to a higher mortality (48%). Although the presentation of CAPS is characterized by multiorgan thrombosis and failure, clinical differences among patients exist based on age and underlying chronic diseases, e.g. malignancy and SLE. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. T2 relaxation time mapping of the cartilage cap of osteochondromas

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hee Kyung; Horn, Paul; Laor, Tal [Cincinnati Children' s Hospital Medical Center, Cincinnati (United States); Daedzinski, Bernard J. [Dept. of Radiology, Children' s Hospital of Philadelphia, University of Pennsylvania, Philadelphia (United States); Kim, Dong Hoon [Dept. of Radiology, Pharmacology, Korea University College of Medicine, Seoul (Korea, Republic of)

    2016-02-15

    Our aim was to evaluate the cartilage cap of osteochondromas using T2 maps and to compare these values to those of normal patellar cartilage, from age and gender matched controls. This study was approved by the Institutional Review Board and request for informed consent was waived. Eleven children (ages 5-17 years) with osteochondromas underwent MR imaging, which included T2-weighted fat suppressed and T2 relaxation time mapping (echo time = 9-99/repetition time = 1500 msec) sequences. Lesion origins were femur (n = 5), tibia (n = 3), fibula (n = 2), and scapula (n = 1). Signal intensity of the cartilage cap, thickness, mean T2 relaxation times, and T2 spatial variation (mean T2 relaxation times as a function of distance) were evaluated. Findings were compared to those of patellar cartilage from a group of age and gender matched subjects. The cartilage caps showed a fluid-like high T2 signal, with mean thickness of 4.8 mm. The mean value of mean T2 relaxation times of the osteochondromas was 264.0 ± 80.4 msec (range, 151.0-366.0 msec). Mean T2 relaxation times were significantly longer than the values from patellar cartilage (39.0 msec) (p < 0.0001). These findings were observed with T2 spatial variation plots across the entire distance of the cartilage cap, with the most pronounced difference in the middle section of the cartilage. Longer T2 relaxation times of the cartilage caps of osteochondromas should be considered as normal, and likely to reflect an increased water content, different microstructure and component.

  3. Seismic explosion sources on an ice cap

    DEFF Research Database (Denmark)

    Shulgin, Alexey; Thybo, Hans

    2015-01-01

    Controlled source seismic investigation of crustal structure below ice covers is an emerging technique. We have recently conducted an explosive refraction/wide-angle reflection seismic experiment on the ice cap in east-central Greenland. The data-quality is high for all shot points and a full...... crustal model can be modelled. A crucial challenge for applying the technique is to control the sources. Here, we present data that describe the efficiency of explosive sources in the ice cover. Analysis of the data shows, that the ice cap traps a significant amount of energy, which is observed...... as a strong ice wave. The ice cap leads to low transmission of energy into the crust such that charges need be larger than in conventional onshore experiments to obtain reliable seismic signals. The strong reflection coefficient at the base of the ice generates strong multiples which may mask for secondary...

  4. Microtubule dynamics: Caps, catastrophes, and coupled hydrolysis

    DEFF Research Database (Denmark)

    Flyvbjerg, H.; Holy, T.E.; Leibler, S.

    1996-01-01

    individual tubulin dimers, an ignored. In this cap model, GTP hydrolysis is assumed to be stochastic and uncoupled to microtubule growth. Different rates of hydrolysis are assumed for GTP in the cap's interior and for GTP at its boundary with hydrolyzed parts of the microtubule. Expectation values...... and probability distributions relating to available experimental data are derived. Caps are found to be short and the total rate of hydrolysis at a microtubule end is found to be dynamically coupled to growth. The so-called catastrophe rate is a simple function of the microtubule growth rare and fits experimental...... of microtubule growth before dilution. The GTP content of microtubules is found and its rare of hydrolysis is determined under the circumstances created in an experiment designed to measure this GTP content. It is concluded that this experiment's failure to register any GTP content is consistent with the model...

  5. Direct observation of strain in InAs quantum dots and cap layer during molecular beam epitaxial growth using in situ X-ray diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Shimomura, Kenichi; Ohshita, Yoshio; Kamiya, Itaru, E-mail: kamiya@toyota-ti.ac.jp [Toyota Technological Institute, 2-12-1 Hisakata, Tempaku, Nagoya 468-8511 (Japan); Suzuki, Hidetoshi [Faculty of Engineering, University of Miyazaki, 1-1 Gakuen Kibanadai-nishi, Miyazaki 889-2192 (Japan); Sasaki, Takuo; Takahasi, Masamitu [Quantum Beam Science Center, Japan Atomic Energy Agency, Koto 1-1-1, Sayo-cho, Hyogo 679-5148 (Japan)

    2015-11-14

    Direct measurements on the growth of InAs quantum dots (QDs) and various cap layers during molecular beam epitaxy are performed by in situ X-ray diffraction (XRD). The evolution of strain induced both in the QDs and cap layers during capping is discussed based on the XRD intensity transients obtained at various lattice constants. Transients with different features are observed from those obtained during InGaAs and GaAs capping. The difference observed is attributed to In-Ga intermixing between the QDs and the cap layer under limited supply of In. Photoluminescence (PL) wavelength can be tuned by controlling the intermixing, which affects both the strain induced in the QDs and the barrier heights. The PL wavelength also varies with the cap layer thickness. A large redshift occurs by reducing the cap thickness. The in situ XRD observation reveals that this is a result of reduced strain. We demonstrate how such information about strain can be applied for designing and preparing novel device structures.

  6. Assembling the CMS yoke end-caps

    CERN Multimedia

    Laurent Guiraud

    2001-01-01

    A crane is used to piece together one of the end-caps that will provide the path for magnetic flux return on the CMS experiment. A total of six end-cap discs will be assembled before being positioned on the barrel yoke to complete the huge 12 500 tonne cylinder yoke. The magnetic field produced will be greater than any other solenoid created to date at 4 T, 100 000 times greater than the Earth's natural magnetic field, and will store enough energy to melt 18 tonnes of gold.

  7. Pharmacy benefit caps and the chronically ill.

    Science.gov (United States)

    Joyce, Geoffrey F; Goldman, Dana P; Karaca-Mandic, Pinar; Zheng, Yuhui

    2007-01-01

    In this paper we examine medication use among retirees with employer-sponsored drug coverage both with and without annual benefit limits. We find that pharmacy benefit caps are associated with higher rates of medication discontinuation across the most common therapeutic classes and that only a minority of those who discontinue use reinitiate therapy once coverage resumes. Plan members who reach their cap are more likely than others to switch plans and increase their rate of generic use; however, in most cases, the shift is temporary. Given the similarities between these plans and Part D, we make some inferences about reforms for Medicare.

  8. Design and implementation of the CAPS receiver

    Institute of Scientific and Technical Information of China (English)

    HU YongHui; HUA Yu; HOU Lei; WEI JingFa; WU JianFeng

    2009-01-01

    In this paper,baaed on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties,the signal power at the port of the receiver antenna is estimated,and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver.A microstrip receiving antenna is designed with high sensitivity and wide beam orientation,the RF front end of the C/A code and P code receivers,and a processor is designed for the navigation baseband.A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time.A software process flow is provided,and research on relatively key techniques is also conducted,such as signal searching,code loop and carrier loop algorithms,a height assistant algorithm,a dual frequency difference speed measurement technique,a speed measurement technique using a single frequency source with frequency assistance,and a CAPS time correcting algorithm,according to the design frame of the receiver hardware.Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m,height accuracy is 1.2-12.8 m,speed measurement accuracy is 0.13-0.3 m/s,dynamic plane positioning accuracy is 24.4 m,height accuracy is 3.0 m,and speed measurement accuracy is 0.24 m/s.In the case of C/A code,the timing accuracy is 200 ha,and it is also shown that the positioning accuracy of the CAPS precise code receiver (1σ) is 5 m from south to north,and 0.8 m from east to west.Finally,research on positioning accuracy is also conducted.

  9. The influence of fibrous bed bulk density on the bed properties

    Directory of Open Access Journals (Sweden)

    Šećerov-Sokolović Radmila M.

    2003-01-01

    Full Text Available The mean properties of seven different fibrous materials and the properties of their different bed bulk densities were investigated. The morphology of the surface, size and geometry were measured by optical microscopy. The bed porosity was measured by the weighing method. The experimental bed permeability, in a high range of bulk density, was calculated from the values of the sanitary water pressure drop at a constant temperature of 15°C, since the data followed Darcy's law. The Reynolds number for a fibrous bed was calculated using a relation from the literature. The Reynolds number was less than 1 for all ranges of fluid velocity. Three empirical relations for fibrous bed permeability were used and compared with the experimental data. It was determined that the empirical data depended on the fiber diameter and fraction of solid in the bed. The relative error linearly increased with increasing fiber diameter.

  10. Unilateral Bimaxillary Idiopathic Fibrous Gingival Hyperplasia with Alveolar Bone Loss- Report of a Rare Case

    Directory of Open Access Journals (Sweden)

    R S Sathawane

    2007-01-01

    Full Text Available Gingival enlargements are of many types and vary according to the etiologic factors and pathologic processes that produce them. Though there are many classifications of gingival enlargement, the most practical one is as follows: 1 Inflammatory gingival enlargement 2 Fibrous gingival hyperplasia 3 Combination of inflammatory and fibrous hyperplasia. Gingival hyperplasia is a heterogeneous group of disorder, which appears clinically as diffuse, firm, and massive enlargement of the gingiva covering most of the crown of the teeth. Idiopathic gingival enlargement is a rare condition of undetermined etiology, although some cases have definite hereditary basis. A case of unilateral idiopathic fibrous gingival hyperplasia on left side of both the jaws with severe bone resorption is presented.

  11. Solitary fibrous tumor of the male breast: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Sessa Fausto

    2008-02-01

    Full Text Available Abstract Extrapleural solitary fibrous tumors are very rare and occasionally they appear in extraserosal soft tissues or parenchymatous organs. In such cases the right preoperative diagnosis is often difficult and challenging, because both radiological and cytological examinations are not exhaustive. For these reasons, surgical excision is frequently the only way to reach the correct diagnosis and to achieve definitive treatment. A few cases of solitary fibrous tumors have been also described in the breast. Although rare, this lesion opens difficulties in preoperative diagnosis entering in differential diagnosis with other benign lesions as well as with breast cancer. In this article we describe a case of a solitary fibrous tumor of the breast in a 49-year-old man. Problems related to differential diagnosis and the possible pitfalls that can be encountered in the diagnostic iter of such rare tumor are discussed.

  12. Electrospinning polyvinylidene fluoride fibrous membranes containing anti-bacterial drugs used as wound dressing.

    Science.gov (United States)

    He, Ting; Wang, Jingnan; Huang, Peilin; Zeng, Baozhen; Li, Haihong; Cao, Qingyun; Zhang, Shiying; Luo, Zhuo; Deng, David Y B; Zhang, Hongwu; Zhou, Wuyi

    2015-06-01

    The aim of this study was to synthesis drug-loaded fibrous membrane scaffolds for potential applications as wound dressing. Polyvinylidene fluoride (PVDF) fibrous membranes were loaded with enrofloxacin (Enro) drugs by using an electrospinning process, and their mechanical strength, drug release profile and anti-bacterial properties were evaluated. Enro drug-loaded PVDF membranes exhibited good elasticity, flexibility and excellent mechanical strength. The electrospinning Enro/PVDF membranes showed a burst drug release in the initial 12h, followed by sustained release for the next 3 days, which was an essential property for antibiotic drugs applied for wound healing. The drug-loaded PVDF fibrous membranes displayed excellent anti-bacterial activity toward Escherichia coli and Staphylococcus aureus. The results suggest that electrospinning PVDF membrane scaffolds loaded with drugs can be used as wound dressing.

  13. Frontonasal and fibrous dysplasia in a patient with unilateral cleft lip and palate.

    Science.gov (United States)

    Weathers, William M; Wolfswinkel, Erik M; Albright, Steven B; Hollier, Larry H; Buchanan, Edward P

    2013-07-01

    Frontonasal dysplasia is a rare entity. It has characteristic physical deformities: hypertelorism, broad nasal root, median facial cleft of the upper lip or palate, clefting of the nasal alae, poorly formed nasal tip, cranium bifidum occultum, and a widow's peak hairline. Fibrous dysplasia is a benign bone tumor in which normal bone is replaced by fibrous, poorly formed osseus tissues. We present a patient with frontonasal dysplasia who desired correction of her hypertelorism. Incidentally, fibrous dysplasia was found in her left orbit complicating surgical correction. In addition, the patient has velopharyngeal insufficiency and a class III malocclusion. The interplay of all these craniofacial defects makes the sequencing and timing of surgery important in this unique patient.

  14. Fibrous dysplasia: rapid malignant transformation into osteogenic sarcoma - A rare occurance

    Directory of Open Access Journals (Sweden)

    S Gon

    2012-09-01

    Full Text Available Malignant transformation of fibrous dysplasia is rare, occurring in less than 1% of cases with a mean lag period of 13.5 years. We report a case of Osteogenic Sarcoma with chondroid differentiation in a pre-existing Fibrous Dysplasia occurring within one year of surgical resection and without any history of exposure to radiation. To the best of our knowledge and extensive search of literature, malignant transformation of Fibrous Dysplasia in such a short period of time, and without history of radiation exposure has never been reported from India.Journal of Pathology of Nepal (2012 Vol. 2, 335-337DOI: http://dx.doi.org/10.3126/jpn.v2i4.6891

  15. A structure-based extracellular matrix expansion mechanism of fibrous tissue growth.

    Science.gov (United States)

    Kalson, Nicholas S; Lu, Yinhui; Taylor, Susan H; Starborg, Tobias; Holmes, David F; Kadler, Karl E

    2015-05-20

    Embryonic growth occurs predominately by an increase in cell number; little is known about growth mechanisms later in development when fibrous tissues account for the bulk of adult vertebrate mass. We present a model for fibrous tissue growth based on 3D-electron microscopy of mouse tendon. We show that the number of collagen fibrils increases during embryonic development and then remains constant during postnatal growth. Embryonic growth was explained predominately by increases in fibril number and length. Postnatal growth arose predominately from increases in fibril length and diameter. A helical crimp structure was established in embryogenesis, and persisted postnatally. The data support a model where the shape and size of tendon is determined by the number and position of embryonic fibroblasts. The collagen fibrils that these cells synthesise provide a template for postnatal growth by structure-based matrix expansion. The model has important implications for growth of other fibrous tissues and fibrosis.

  16. Solitary fibrous tumor of the sellar region treated with adjuvant radiation therapy

    Science.gov (United States)

    Sahai, Puja; Singh, Geetika; Mondal, Dodul; Suri, Vaishali; Julka, Pramod Kumar

    2016-01-01

    The solitary fibrous tumor of central nervous system is rare. Herein, a case of solitary fibrous tumor arising from sellar region is described. A 60-year-old man underwent subtotal excision of the tumor because of extensive infiltration of optical and vascular structures. In view of the presence of residual tumor, he was treated with adjuvant radiation therapy. After a follow-up period of 1 year, there was no progression of the lesion evident on magnetic resonance imaging of the brain. Solitary fibrous tumor should be considered as one of the differential diagnosis of a mass lesion arising in sellar region. Immunohistochemistry with CD34 is valuable for discerning the diagnosis. Complete surgery should be the goal of treatment and adjuvant radiation therapy may be considered for residual or recurrent disease. PMID:27695561

  17. A Novel Method to Decrease Micro-residual Stresses of Fibrous Composites by Adding Carbon Nanotube

    Directory of Open Access Journals (Sweden)

    M. M. Shokrieh

    2013-12-01

    Full Text Available In this research, a novel method to decrease micro-residual stresses of fibrous composites by adding carbon nanotubes (CNTs is proposed in detail. The negative coefficient of thermal expansion and the high young’s modulus of CNTs can be utilized to counterbalance the process induced residual stresses in composites. To this end, first, the effects of adding CNTs to the matrix of fibrous composites in reducing the coefficient of thermal expansion (CTE and increasing of young’s modulus of matrix are studied theoretically. Then, a three phase micromechanical model (the energy method is used to model the effect of CNT in reducing the residual stresses of fibrous composites. The results show that by addition of CNTs, enhancements in properties of matrix are obtained and lead to decrease in micro-residual stresses of matrix and fiber up to 72%.

  18. A New Device for Characterisation of the Drainage Kinetics of Fibrous Suspensions Under Gravity

    Directory of Open Access Journals (Sweden)

    Przybysz Piotr

    2014-12-01

    Full Text Available Gravity dewatering of fibrous suspension is one of basic technological operations in paper production process. Although there are numerous methods to determine dewatering of such suspensions, none of them can measure undisturbed flow of removed water. In the paper the idea and design of a new apparatus for the determination of drainage rate of fibrous suspensions is presented. The apparatus differs from other known devices by minimisation of filtrate flow resistance in the outlet part of the equipment. In the second part of the paper measurements of the drainage rate have been presented. The flow resistance of the fluid through the bottom wire screen in the device was determined. The calculated flow resistance will be used in the developed model of dynamic drainage of fibrous suspensions, which will be discussed in our following paper (Przybysz et al., 2014.

  19. Chemostratigraphy and lithological characters of Neoproterozoic cap carbonates from the Kuruktag Mountain, Xinjiang, western China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The Neoproterozoic Era includes some of the most largest ice ages in the geological history.The exact number of glaciations is unknown,though there were at least two events of global glaciation.Neoproterozoic glacial deposits in the Kurukmg Mountain,Xinjiang,western China have proven that there had occurred three discrete Neoproterozoic glaciations.Diamictite units occurred in the Bassi,Tereeken,and Hankalchough formations,carbonate units were recognized among the diamictites and immediately overlied the Bayisi,Tereeken and Hankalchough diamictites.Carbonates at the top of the Bayisi Formation are characterized by the dolo-sility stones with negative δ13C values ranging from-4.10‰ to-8.17‰(PDB),comparable to the Sturtian cap carbonates that overlie the Sturtian glacial deposits from other Neoproterozoic sequences.Carbonates overlying the Tereeken Formation are characterized by the pinkish cap dolostones fca.10 m thick)with negative δ13C values railging from -2.58‰ to-4.77‰(PDB),comparable to the Marinoan cap carbonates,The cap is alao characterized by tepee-like structures,barite precipitates and pseudomorphous aragonite crystal fan limestones.Carbonates at the top of the Hankalchough Formation are characterized by subaerial exposure crust(vadose pisolite structure,calcareous crust structure)dolostones with negative δ13C values ranging from-4.56‰δto-11.45‰(PDB)and the calcareous crust dolostones,implying that the Hankalchough cap carbonates differ from either the Sturtian or Marinoan cap carbonates in sedimentary environment and carbon isotopic composition.In addition,it is suggested the Hankalchough glaciation belongs to a terrestrial glaciation and it is the third largest glaciation during the Neoproterozoic period on the Tarim platform.

  20. Anti-inflammatory, anti-bacterial, and cytotoxic activity of fibrous clays.

    Science.gov (United States)

    Cervini-Silva, Javiera; Nieto-Camacho, Antonio-; Ramírez-Apan, María Teresa; Gómez-Vidales, Virginia; Palacios, Eduardo; Montoya, Ascención; Ronquillo de Jesús, Elba

    2015-05-01

    Produced worldwide at 1.2m tons per year, fibrous clays are used in the production of pet litter, animal feed stuff to roof parcels, construction and rheological additives, and other applications needing to replace long-fiber length asbestos. To the authors' knowledge, however, information on the beneficial effects of fibrous clays on health remains scarce. This paper reports on the anti-inflammatory, anti-bacterial, and cytotoxic activity by sepiolite (Vallecas, Spain) and palygorskite (Torrejon El Rubio, Spain). The anti-inflammatory activity was determined using the 12-O-tetradecanoylphorbol-13-acetate (TPA) and myeloperoxidase (MPO) methods. Histological cuts were obtained for quantifying leukocytes found in the epidermis. Palygorkite and sepiolite caused edema inhibition and migration of neutrophils ca. 68.64 and 45.54%, and 80 and 65%, respectively. Fibrous clays yielded high rates of infiltration, explained by cleavage of polysomes and exposure of silanol groups. Also, fibrous clays showed high inhibition of myeloperoxidase contents shortly after exposure, but decreased sharply afterwards. In contrast, tubular clays caused an increasing inhibition of myeloperoxidase with time. Thus, clay structure restricted the kinetics and mechanism of myeloperoxidase inhibition. Fibrous clays were screened in vitro against human cancer cell lines. Cytotoxicity was determined using the protein-binding dye sulforhodamine B (SRB). Exposing cancer human cells to sepiolite or palygorskite showed growth inhibition varying with cell line. This study shows that fibrous clays served as an effective anti-inflammatory, limited by chemical transfer and cellular-level signals responding exclusively to an early exposure to clay, and cell viability decreasing significantly only after exposure to high concentrations of sepiolite.

  1. Electrospun PVdF-based fibrous polymer electrolytes for lithium ion polymer batteries

    Energy Technology Data Exchange (ETDEWEB)

    Jeong Rae Kim [Hanyang University, Seoul (France). Applied Chemical Engineering Division; Korea Institute of Science and Technology, Seoul (Korea). Polymer Hybrid Research Center; Sung Won Choi [Yonsei University, Seoul (Korea). Department of Chemistry; Seong Mu Jo; Wha Seop Lee [Korea Institute of Science and Technology, Seoul (Korea). Polymer Hybrid Research Center; Byung Chul Kim [Hanyang University, Seoul (France). Applied Chemical Engineering Division

    2004-11-15

    This paper discusses the preparation of microporous fibrous membranes from PVdF solutions with different polymer contents, using the electrospinning technique. Electrospun PVdF-based fibrous membranes with average fiber diameters (AFD's) of 0.45-1.38 {mu}m have an apparent porosity and a mean pore size (MPS) of 80-89% and 1.1-4.3 {mu}m, respectively. They exhibited a high uptake of the electrolyte solution (320-350%) and a high ionic conductivity of above 1 x 10{sup -3} s/cm at room temperature. Their ionic conductivity increased with the decrease in the AFD of the fibrous membrane due to its high electrolyte uptake. The interaction between the electrolyte molecules and the PVdF with a high crystalline content may have had a minor effect on the lithium ion transfer in the fibrous polymer electrolyte, unlike in a nanoporous gel polymer electrolyte. The fibrous polymer electrolyte that contained a 1 M LiPF{sub 6}-EC/DMC/DEC (1/1/1 by weight) solution showed a high electrochemical stability of above 5.0 V, which increased with the decrease in the AFD. The interfacial resistance (R{sub i}) between the polymer electrolyte and the lithium electrode slightly increased with the storage time, compared with the higher increase in the interfacial resistance of other gel polymer electrolytes. The prototype cell (MCMB/PVdF-based fibrous electrolyte/LiCoO{sub 2}) showed a very stable charge-discharge behavior with a slight capacity loss under constant current and voltage conditions at the C/2-rate of 20 and 60 {sup o}C. (author)

  2. Electrospun PVdF-based fibrous polymer electrolytes for lithium ion polymer batteries

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jeong Rae [Applied Chemical Engineering Division, Hanyang University, 17, Haengdang-dong, Seongdong-Ku, Seoul 133-791 (Korea, Republic of); Polymer Hybrid Research Center, Korea Institute of Science and Technology, 39-1, Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Choi, Sung Won [Department of Chemistry, Yonsei University, 134, Sinchon-dong, Seodaemun-gu, Seoul 120-749 (Korea, Republic of); Polymer Hybrid Research Center, Korea Institute of Science and Technology, 39-1, Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Jo, Seong Mu [Polymer Hybrid Research Center, Korea Institute of Science and Technology, 39-1, Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of)]. E-mail: smjo@kist.re.kr; Lee, Wha Seop [Polymer Hybrid Research Center, Korea Institute of Science and Technology, 39-1, Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Kim, Byung Chul [Applied Chemical Engineering Division, Hanyang University, 17, Haengdang-dong, Seongdong-Ku, Seoul 133-791 (Korea, Republic of)

    2004-11-15

    This paper discusses the preparation of microporous fibrous membranes from PVdF solutions with different polymer contents, using the electrospinning technique. Electrospun PVdF-based fibrous membranes with average fiber diameters (AFD's) of 0.45-1.38 {mu}m have an apparent porosity and a mean pore size (MPS) of 80-89% and 1.1-4.3 {mu}m, respectively. They exhibited a high uptake of the electrolyte solution (320-350%) and a high ionic conductivity of above 1 x 10{sup -3} s/cm at room temperature. Their ionic conductivity increased with the decrease in the AFD of the fibrous membrane due to its high electrolyte uptake. The interaction between the electrolyte molecules and the PVdF with a high crystalline content may have had a minor effect on the lithium ion transfer in the fibrous polymer electrolyte, unlike in a nanoporous gel polymer electrolyte. The fibrous polymer electrolyte that contained a 1 M LiPF{sub 6}-EC/DMC/DEC (1/1/1 by weight) solution showed a high electrochemical stability of above 5.0 V, which increased with the decrease in the AFD The interfacial resistance (R{sub i}) between the polymer electrolyte and the lithium electrode slightly increased with the storage time, compared with the higher increase in the interfacial resistance of other gel polymer electrolytes. The prototype cell (MCMB/PVdF-based fibrous electrolyte/LiCoO{sub 2}) showed a very stable charge-discharge behavior with a slight capacity loss under constant current and voltage conditions at the C/2-rate of 20 and 60 deg. C.

  3. Bayesian inference of ice thickness from remote-sensing data

    Science.gov (United States)

    Werder, Mauro A.; Huss, Matthias

    2017-04-01

    Knowledge about ice thickness and volume is indispensable for studying ice dynamics, future sea-level rise due to glacier melt or their contribution to regional hydrology. Accurate measurements of glacier thickness require on-site work, usually employing radar techniques. However, these field measurements are time consuming, expensive and sometime downright impossible. Conversely, measurements of the ice surface, namely elevation and flow velocity, are becoming available world-wide through remote sensing. The model of Farinotti et al. (2009) calculates ice thicknesses based on a mass conservation approach paired with shallow ice physics using estimates of the surface mass balance. The presented work applies a Bayesian inference approach to estimate the parameters of a modified version of this forward model by fitting it to both measurements of surface flow speed and of ice thickness. The inverse model outputs ice thickness as well the distribution of the error. We fit the model to ten test glaciers and ice caps and quantify the improvements of thickness estimates through the usage of surface ice flow measurements.

  4. Cystic fibrous osteodystrophy of the jaw in two pet kinkajous (Potos flavus).

    Science.gov (United States)

    Garma-Aviña, A; Torres-Montoya, J

    1998-11-07

    Two kinkajous (Potos flavus), which were separately owned as pets and fed an inappropriate diet consisting almost exclusively of succulent fruits developed cystic fibrous osteodystrophy of the jaw. In both cases there was a prominent enlargement of the chin and lower jaw, decalcification of facial bones, softening of the gingiva, and severe malocclusion, but no other relevant changes. Clinical, radiographic and histological findings were consistent with cystic fibrous osteodystrophy. The findings suggest that kinkajous with this condition are particularly prone to developing a bulbous enlargement of the chin as the main clinical sign, and that this change is histologically similar to the cystic form of the disease observed in man and monkeys.

  5. Exploiting BSA to Inhibit the Fibrous Aggregation of Magnetic Nanoparticles under an Alternating Magnetic Field

    Directory of Open Access Journals (Sweden)

    Ning Gu

    2013-03-01

    Full Text Available The alternating magnetic field was discovered to be capable of inducing the fibrous aggregation of magnetic nanoparticles. However, this anisotropic aggregation may be unfavorable for practical applications. Here, we reported that the adsorption of BSA (bovine serum albumin on the surfaces of magnetic nanoparticles can effectively make the fibrous aggregation of γ-Fe2O3 nanoparticles turn into a more isotropic aggregation in the presence of the alternating magnetic field. Also, the heating curves with and without BSA adsorption under different pH conditions were measured to show the influence of the colloidal aggregation states on the collective calorific behavior of magnetic nanoparticles.

  6. Cushing syndrome, sexual precocity, and polyostotic fibrous dysplasia (Albright syndrome) in infancy.

    Science.gov (United States)

    Danon, M; Robboy, S J; Kim, S; Scully, R; Crawford, J D

    1975-12-01

    The sexual precocity of polyostotic fibrous dysplasia is occasionally accompanied by other endocrine disorders, but in only two previous instances has Cushing syndrome been reported. The history of a 6-month-old girl is presented, in whom this syndrome was complicated by congenital Cushings syndrome. Although endocrinopathies of polyostotic fibrous dysplasia have usually been ascribed to a central (hypothalamic) origin, the findings in this patient suggest autonomous hyperfunction of the peripheral endocrine glands, with the Cushing syndrome caused by hyperplastic nodules in the adrenal glands and the precocity by luteinized follicular cysts of the ovary.

  7. Malignant Solitary Fibrous Tumor of the Kidney: Report of the First Case Managed with Interferon

    Directory of Open Access Journals (Sweden)

    Javier Cuello

    2013-01-01

    Full Text Available Solitary fibrous tumors of the kidney are extremely rare tumors with unpredictable behavior. We describe a case of a patient with a solitary fibrous tumor of kidney with malignant findings with distant metastasis and nephrectomy managed with subcutaneous interferon achieving 23 months of progression-free survival. To date there is no prospective evaluation of any specific modality of treatment, but the surgical management and long-term followup are the only ones so far recommended strategies in the management of these patients. Studies are awaited with more patients to evaluate the different strategies of systemic therapy reported so far to allow adding survival benefit.

  8. Malignant solitary fibrous tumor of the kidney: report of the first case managed with interferon.

    Science.gov (United States)

    Cuello, Javier; Brugés, Ricardo

    2013-01-01

    Solitary fibrous tumors of the kidney are extremely rare tumors with unpredictable behavior. We describe a case of a patient with a solitary fibrous tumor of kidney with malignant findings with distant metastasis and nephrectomy managed with subcutaneous interferon achieving 23 months of progression-free survival. To date there is no prospective evaluation of any specific modality of treatment, but the surgical management and long-term followup are the only ones so far recommended strategies in the management of these patients. Studies are awaited with more patients to evaluate the different strategies of systemic therapy reported so far to allow adding survival benefit.

  9. Solitary fibrous tumor of the larynx: report of two new cases

    Directory of Open Access Journals (Sweden)

    Fábio Muradás Girardi

    2014-06-01

    Full Text Available Solitary fibrous tumor is a rare neoplasm. Few cases have been described in the head and neck area, and less than 11 were located in the larynx. We described two new cases of solitary fibrous tumor of the larynx. A man, 64-year-old, and a woman, 77-year-old, both with submucosal and nodular supraglottic lesions, were submitted to surgical treatment and both showed CD-34 and bcl-2 immunoreactivity and S-100 and smooth-muscle actin negativity. After 24 and 22 months of postoperative follow-up, respectively, they did not show signs of active disease.

  10. Massive fibrous epulis-a case report of a 10-year-old lesion

    Institute of Scientific and Technical Information of China (English)

    Gabriel MFonseca; Ricardo MFonseca; Mario Cantn

    2014-01-01

    The fibrous epulis, a common tumor-like lesion of the gingiva, appears in the interdental papilla as a result of local irritation. Lesions are asymptomatic and have a variable growth rate. A 75-year-old woman was referred for the evaluation of a large painless gingival mass. It had started 10 years back and has been increasing in size the last year. No bone involvement was noted. The tumor was totally removed by excision with surgical scalpel under local anesthesia without teeth extraction. The microscopic findings were suggestive of a fibrous epulis. Differential diagnosis, clinical considerations and factors to prevent recurrence are discussed.

  11. Monostostic fibrous dysplasia with nonspecific cystic degeneration: A case report and review of literature

    Directory of Open Access Journals (Sweden)

    Afreen Nadaf

    2013-01-01

    Full Text Available Fibrous dysplasia (FD has been regarded as a developmental skeletal disorder characterized by replacement of normal bone with benign cellular fibrous connective tissue. It has now become evident that FD is a genetic disease caused by somatic activating mutation of the Gsα subunit of G protein-coupled receptor. Here we report a case of bilateral monostotic FD in a middle-aged female showing a classic histological picture, but radiologically presenting as a mixed radiolucent radiopaque lesion showing nonspecific cystic degeneration.

  12. Nanoscale Piezoelectric Properties of Self-Assembled Fmoc-FF Peptide Fibrous Networks.

    Science.gov (United States)

    Ryan, Kate; Beirne, Jason; Redmond, Gareth; Kilpatrick, Jason I; Guyonnet, Jill; Buchete, Nicolae-Viorel; Kholkin, Andrei L; Rodriguez, Brian J

    2015-06-17

    Fibrous peptide networks, such as the structural framework of self-assembled fluorenylmethyloxycarbonyl diphenylalanine (Fmoc-FF) nanofibrils, have mechanical properties that could successfully mimic natural tissues, making them promising materials for tissue engineering scaffolds. These nanomaterials have been determined to exhibit shear piezoelectricity using piezoresponse force microscopy, as previously reported for FF nanotubes. Structural analyses of Fmoc-FF nanofibrils suggest that the observed piezoelectric response may result from the noncentrosymmetric nature of an underlying β-sheet topology. The observed piezoelectricity of Fmoc-FF fibrous networks is advantageous for a range of biomedical applications where electrical or mechanical stimuli are required.

  13. Application of Transistors in Textiles: Monitoring Water Transportation Behaviour in Fibrous Assemblies

    Science.gov (United States)

    Chatterjee, Arobindo; Singh, Pratibha; Ghosh, Subrata

    2016-11-01

    Simple semiconductor device has been used for amplifying the analog signals, obtained with the change in electrical resistance in fibrous assembly and converting these amplified copies of signals to digital signals. This paper deals with the application of transistors as amplifier, as well as switch. Different circuit configurations using transistors have been tried for sensing and reciprocating the real time data on suitable display device. It is found that transistors configured as common-emitter amplifiers can precisely sense the liquid at the surface of fibrous assembly at different levels with respect to time.

  14. Endemic pleural disease associated with exposure to mixed fibrous dust in Turkey

    Energy Technology Data Exchange (ETDEWEB)

    Rohl, A.N.; Langer, A.M.; Moncure, G.; Selikoff, I.J.; Fischbein, A.

    1982-04-30

    Pleural mesothelioma, lung cancer, pleural calcification and fibrosis, and interstitial parenchymal fibrosis have been observed among inhabitants of several villages in south-central Turkey. Earlier reports have stated that environmental and lung tissue samples from this area contained the fibrous zeolite mineral erionite, and this mineral has generally been assumed to be the agent responsible for these endemic pathological conditions in the absence of asbestos outcroppings and usage. Several different kinds of asbestos minerals in addition to erionite have now been found in environmental samples taken from the villages where these diseases occur. The lung tissues of mesothelioma patients from these villages contain both fibrous zeolites and asbestos minerals.

  15. Nitridated fibrous silica (KCC-1) as a sustainable solid base nanocatalyst

    KAUST Repository

    Bouhrara, Mohamed

    2013-09-03

    We observed that support morphology has dramatic effects on the performance of nitridated silica as a base. By simply replacing conventional silica supports (such as SBA-15 and MCM-41) with fibrous nanosilica (KCC-1), we observed multifold enhancement in the catalytic activity of the nitridated solid base for Knoevenagel condensations and transesterification reactions. This enhancement of the activity can be explained by amine accessibility, which is excellent in KCC-1 due to its open and flexible fibrous structure, that facilitates penetration and interaction with basic amine sites. © 2013 American Chemical Society.

  16. SNP2CAPS: a SNP and INDEL analysis tool for CAPS marker development

    OpenAIRE

    Thiel, Thomas; Kota, Raja; Grosse, Ivo; Stein, Nils; Graner, Andreas

    2004-01-01

    With the influx of various SNP genotyping assays in recent years, there has been a need for an assay that is robust, yet cost effective, and could be performed using standard gel-based procedures. In this context, CAPS markers have been shown to meet these criteria. However, converting SNPs to CAPS markers can be a difficult process if done manually. In order to address this problem, we describe a computer program, SNP2CAPS, that facilitates the computational conversion of SNP markers into CA...

  17. Low-level laser therapy and vibration therapy for the treatment of localized adiposity and fibrous cellulite.

    Science.gov (United States)

    Savoia, Antonella; Landi, Simone; Vannini, Fulvio; Baldi, Alfonso

    2013-06-01

    In recent years, there has been an upsurge in the application of low-level laser therapy in various medical diseases. Additionally, vibration therapy is a new and effective measure to prevent muscular atrophy and osteoporosis, along with some general health-related beneficial effects of exercise on skeletal muscles such as improvement of endothelial function and an increased enzyme capacity of energy metabolism. The aim of this study was to evaluate the application of a 635 nm and 0.040 W exit power per multiple diode laser in combination with vibration therapy for the application of non-invasive reduction of circumference in patients with localized adiposity and cellulite. The study enrolled men and women (N = 33) aged 18-64 years with localized adiposity or fibrous cellulite. The evaluation parameters were: photographic evaluation, perimetric evaluation, blood tests, ecographic evaluation, histological evaluation, and subjective and objective tests. The results produced were statistically analyzed and resulted in a significant reduction of fat thickness when compared to the measurement prior to the treatment (P cellulite.

  18. Mapping of p140Cap phosphorylation sites

    DEFF Research Database (Denmark)

    Repetto, Daniele; Aramu, Simona; Boeri Erba, Elisabetta

    2013-01-01

    Protein phosphorylation tightly regulates specific binding of effector proteins that control many diverse biological functions of cells (e. g. signaling, migration and proliferation). p140Cap is an adaptor protein, specifically expressed in brain, testis and epithelial cells, that undergoes phosp...

  19. Knowledge Management at Cap Gemini Nederland

    NARCIS (Netherlands)

    M.J. Vlaanderen (Marie Jose)

    1998-01-01

    textabstractThe theme of this paper is knowledge management (KM) at an organization that provides information technology (IT) services. It is based on the results of a KM-survey of the Finance Division of Cap Gemini (CG) conducted during the spring of 1997.

  20. ATLAS: End-cap Toroid assembly

    CERN Multimedia

    2006-01-01

    In building 191 and building 180- assembly of this massive piece.To reach the top of the end-cap the cranes has to be used and during the assembly you can see welding and hear many tools running background.

  1. CAP Reform and the Doha Development Agenda

    NARCIS (Netherlands)

    van Dijck, P.; Faber, G.

    2004-01-01

    The CAP reforms that the EU accepted in June 2003 will partially decouple direct income payments to farmers from production and make these payments conditional on cross-compliance. The reforms are driven by enlargement of EU membership, budgetary constraints, mounting pressures from diverse animal w

  2. Knowledge Management at Cap Gemini Nederland

    NARCIS (Netherlands)

    M.J. Vlaanderen (Marie Jose)

    1998-01-01

    textabstractThe theme of this paper is knowledge management (KM) at an organization that provides information technology (IT) services. It is based on the results of a KM-survey of the Finance Division of Cap Gemini (CG) conducted during the spring of 1997.

  3. The Effectiveness of Caps on Political Lobbying

    NARCIS (Netherlands)

    Matejka, M.; Onderstal, A.M.; De Waegenaere, A.M.B.

    2002-01-01

    In this paper, we analyze a lobby game, modelled as an all-pay auction in which interest groups submit bids in order to obtain a political prize.The bids are restricted to be below a cap imposed by the government.For both an incomplete and a complete information setting we show the following results

  4. Invasive fibrous thyroiditis (Riedel's struma): a manifestation of multifocal fibrosclerosis? A case report with review of the literature.

    NARCIS (Netherlands)

    Lange, W E de; Freling, N J; Molenaar, W M; Doorenbos, H

    1989-01-01

    A patient is described with Riedel's thyroiditis and invasive fibrous growth in parathyroid, lacrimal glands, and retroperitoneally. It is proposed that Riedel's thyroiditis is not a disease in its own right but a manifestation of a generalized disease of fibrous tissues.

  5. Antibacterial and anti-adhesion effects of the silver nanoparticles-loaded poly(L-lactide) fibrous membrane

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Shen [Department of Orthopaedics, Shanghai Sixth People' s Hospital, Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai 200233 (China); Zhao, Jingwen [Orthopedic Institute, Soochow University, 708 Renmin Road, Suzhou, Jiangsu 215007 (China); School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Hua Shan Road, Shanghai 200030 (China); Ruan, Hongjiang; Wang, Wei [Department of Orthopaedics, Shanghai Sixth People' s Hospital, Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai 200233 (China); Wu, Tianyi [Department of Orthopaedic Surgery, 2nd Affiliated hospital of Nanjing Medical University, Nanjing Medical University, 121 Jiang Jia Yuan, Nanjing 210011 (China); Cui, Wenguo, E-mail: wgcui80@hotmail.com [Orthopedic Institute, Soochow University, 708 Renmin Road, Suzhou, Jiangsu 215007 (China); School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Hua Shan Road, Shanghai 200030 (China); Fan, Cunyi, E-mail: fancunyi888@hotmail.com [Department of Orthopaedics, Shanghai Sixth People' s Hospital, Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai 200233 (China)

    2013-04-01

    The complications of tendon injury are frequently compromised by peritendinous adhesions and tendon sheath infection. Physical barriers for anti-adhesion may increase the incidence of postoperative infection. This study was designed to evaluate the potential of silver nanoparticles (AgNPs)-loaded poly(L-lactide) (PLLA) electrospun fibrous membranes to prevent adhesion formation and infection. Results of an in vitro drug release study showed that a burst release was followed by sustained release from electrospun fibrous membranes with a high initial silver content. Fewer fibroblasts adhered to and proliferated on the AgNP-loaded PLLA electrospun fibrous membranes compared with pure PLLA electrospun fibrous membrane. In the antibacterial test, the AgNP-loaded PLLA electrospun fibrous membranes can prevent the adhesion of Gram-positive Staphylococcus aureus and Staphylococcus epidermidis and Gram-negative Pseudomonas aeruginosa. Taken together, these results demonstrate that AgNP-loaded PLLA electrospun fibrous membranes have the convenient practical medical potential of reduction of infection and adhesion formation after tendon injury. - Highlights: ► Silver nanoparticles are directly electrospun into PLLA fibrous membrane. ► Long-lasting release of Ag + ions is achieved. ► Cytotoxicity of silver ions benefits the anti-proliferation of physical barriers. ► Broad anti-microbial effect of drug-loaded fibrous membrane is revealed. ► Antibacterial and anti-adhesion effects of the physical barriers are combined.

  6. Design of multi-layered porous fibrous metals for optimal sound absorption in the low frequency range

    Directory of Open Access Journals (Sweden)

    Wenjiong Chen

    2016-01-01

    Full Text Available We present a design method for calculating and optimizing sound absorption coefficient of multi-layered porous fibrous metals (PFM in the low frequency range. PFM is simplified as an equivalent idealized sheet with all metallic fibers aligned in one direction and distributed in periodic hexagonal patterns. We use a phenomenological model in the literature to investigate the effects of pore geometrical parameters (fiber diameter and gap on sound absorption performance. The sound absorption coefficient of multi-layered PFMs is calculated using impedance translation theorem. To demonstrate the validity of the present model, we compare the predicted results with the experimental data. With the average sound absorption (low frequency range as the objective function and the fiber gaps as the design variables, an optimization method for multi-layered fibrous metals is proposed. A new fibrous layout with given porosity of multi-layered fibrous metals is suggested to achieve optimal low frequency sound absorption. The sound absorption coefficient of the optimal multi-layered fibrous metal is higher than the single-layered fibrous metal, and a significant effect of the fibrous material on sound absorption is found due to the surface porosity of the multi-layered fibrous.

  7. Effect of heating rate on temperature of titanium alloy (. cap alpha. +. beta. ). -->. beta. transformaton

    Energy Technology Data Exchange (ETDEWEB)

    Gridnev, V.N.; Ivasishin, O.M.; Markovskij, P.E. (AN Ukrainskoj SSR, Kiev. Inst. Metallofiziki)

    1985-01-01

    The effect of doping of two-phase titaniums alloys and morphology of initial structure on the Tsub(t) temperature shift value of (..cap alpha..+..beta..)..--> beta.. transformation depending on heating rate is investigated. It has been found that the Tsub(t) shift occurs in the strictly determined temperature range depending on chemical alloy composition. The Tsub(t) shift is directly proportional to the Ksub(..beta..) coefficient applied as a quantitative alloying characteristic as well as a dimensional factor equal either to the plate thickness or the ..cap alpha..-phase globule diameter depending on the type of initial structure. In the limits of this temperature range the (..cap alpha..+..beta..)..--> beta..-transformation occurs completely according to the diffusion mechanism. The critical heating rate at which maximum permissible Tsub(t) value is attained and above which its stabilization is observed is determined by the same parameters - the alloy doping degree characterized by the Ksub(..beta..) coefficient and the ..cap alpha..-phase crystal dimensions in the initial structure.

  8. Investigating the effect of capping layers on final thin film morphology after a dewetting process

    Science.gov (United States)

    White, Benjamin C.

    Nanoparticles on a substrate have numerous applications in nanotechnology, from enhancements to solar cell efficiency to improvements in carbon nanotube growth. Producing nanoparticles in a cheap fashion with some control over size and spacing is difficult to do, but desired. This work presents a novel method for altering the radius and pitch distributions of nickel and gold nanoparticles in a scalable fashion. The introduction of alumina capping layers to thin nickel films during a pulsed laser-induced dewetting process has yielded reductions in the mean and standard deviation of radii and pitch for dewet nanoparticles. Carbon nanotube mats grown on these samples show a much thicker mat for the capped case. The same capping layers have produced an opposite effect of increased nanoparticle size and spacing during a solid state dewetting process of a gold film. These results also show a decrease in the magnitude of the effect as the capping layer thickness increases. Since the subject of research interest for using these nanoparticles has shifted towards producing ordered arrays with size and spacing control, the uncertainty in the values of these distributions needs to be quantified for any form of meaningful comparison to be made between fabrication methods. Presented here is a first step in the uncertainty analysis of such samples via synthetic images producing error distributions.

  9. How thick is the lithosphere?

    Science.gov (United States)

    Kanamori, H; Press, F

    1970-04-25

    A rapid decrease in shear velocity in the suboceanic mantle is used to infer the thickness of the lithosphere. It is proposed that new and highly precise group velocity data constrain the solutions and imply a thickness near 70 km.

  10. CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

    Science.gov (United States)

    Jockusch, Wolf J; Speidel, Dina; Sigler, Albrecht; Sørensen, Jakob B; Varoqueaux, Frederique; Rhee, Jeong-Seop; Brose, Nils

    2007-11-16

    Before transmitter-filled synaptic vesicles can fuse with the plasma membrane upon stimulation they have to be primed to fusion competence. The regulation of this priming process controls the strength and plasticity of synaptic transmission between neurons, which in turn determines many complex brain functions. We show that CAPS-1 and CAPS-2 are essential components of the synaptic vesicle priming machinery. CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, which causes a selective impairment of fast phasic transmitter release. Increases in the intracellular Ca(2+) levels can transiently revert this defect. Our findings demonstrate that CAPS proteins generate and maintain a highly fusion competent synaptic vesicle pool that supports phasic Ca(2+) triggered release of transmitters.

  11. Fibrous dysplasia associated with primary hyperparathyroidism absent of McCune-albright syndrome: Tc-99m MDP findings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seong Jang; Seok, Ju Won; Kim, In Ju; Kim, Yong Ki; Kim, Dong Soo [Pusan National University College of Medicine, Pusan (Korea, Republic of)

    2003-04-01

    Fibrous dysplasia is a chronic disorder of the skeleton that causes expansion of one or more bones due to abnormal development of the fibrous, or connective tissue within the bone. The abnormality will cause uneven growth, brittleness and deformity in affected bones. Some patients have only one bone affected, whereas other patients have numerous bones affected. While any bone can be affected by fibrous dysplasia, the most common sites of the disease are the femur, tibia, ribs, skull, facial bones, humerus, and pelvis. In conclusion, Tc-99m MDP bone scan as well as Tc-99m MIBI scan may be useful for the detection of fibrous dysplasia. Also, factors responsible for the uptake of MIBI by fibrous dysplasia will need to be studied further.

  12. Thick-Big Descriptions

    DEFF Research Database (Denmark)

    Lai, Signe Sophus

    The paper discusses the rewards and challenges of employing commercial audience measurements data – gathered by media industries for profitmaking purposes – in ethnographic research on the Internet in everyday life. It questions claims to the objectivity of big data (Anderson 2008), the assumption...... communication systems, language and behavior appear as texts, outputs, and discourses (data to be ‘found’) – big data then documents things that in earlier research required interviews and observations (data to be ‘made’) (Jensen 2014). However, web-measurement enterprises build audiences according...... to a commercial logic (boyd & Crawford 2011) and is as such directed by motives that call for specific types of sellable user data and specific segmentation strategies. In combining big data and ‘thick descriptions’ (Geertz 1973) scholars need to question how ethnographic fieldwork might map the ‘data not seen...

  13. Specificity of recognition of mRNA 5' cap by human nuclear cap-binding complex.

    Science.gov (United States)

    Worch, Remigiusz; Niedzwiecka, Anna; Stepinski, Janusz; Mazza, Catherine; Jankowska-Anyszka, Marzena; Darzynkiewicz, Edward; Cusack, Stephen; Stolarski, Ryszard

    2005-09-01

    The heterodimeric nuclear cap-binding complex (CBC) binds to the mono-methylated 5' cap of eukaryotic RNA polymerase II transcripts such as mRNA and U snRNA. The binding is important for nuclear maturation of mRNAs and possibly in the first round of translation and nonsense-mediated decay. It is also essential for nuclear export of U snRNAs in metazoans. We report characterization by fluorescence spectroscopy of the recognition of 5' capped RNA by human CBC. The association constants (K(as)) for 17 mono- and dinucleotide cap analogs as well as for the oligomer m7GpppA(m2') pU(m2')pA(m2') cover the range from 1.8 x 10(6) M(-1) to 2.3 x 10(8) M(-1). Higher affinity for CBC is observed for the dinucleotide compared with mononucleotide analogs, especially for those containing a purine nucleoside next to m7G. The mRNA tetramer associates with CBC as tightly as the dinucleotide analogs. Replacement of Tyr138 by alanine in the CBP20 subunit of CBC reduces the cap affinity except for the mononucleotide analogs, consistent with the crystallographic observation of the second base stacking on this residue. Our spectroscopic studies showed that contrary to the other known cap-binding proteins, the first two nucleotides of a capped-RNA are indispensable for its specific recognition by CBC. Differences in the cap binding of CBC compared with the eukaryotic translation initiation factor 4E (eIF4E) are analyzed and discussed regarding replacement of CBC by eIF4E.

  14. Disentangling The Thick Concept Argument

    DEFF Research Database (Denmark)

    Blomberg, Olle

    2007-01-01

    Critics argue that non-cognitivism cannot adequately account for the existence and nature of some thick moral concepts. They use the existence of thick concepts as a lever in an argument against non-cognitivism, here called the Thick Concept Argument (TCA). While TCA is frequently invoked...

  15. Disentangling The Thick Concept Argument

    DEFF Research Database (Denmark)

    Blomberg, Olle

    2007-01-01

    Critics argue that non-cognitivism cannot adequately account for the existence and nature of some thick moral concepts. They use the existence of thick concepts as a lever in an argument against non-cognitivism, here called the Thick Concept Argument (TCA). While TCA is frequently invoked...

  16. Facially amphiphilic thiol capped gold and silver nanoparticles

    Indian Academy of Sciences (India)

    Shreedhar Bhata; Uday Maitra

    2008-11-01

    A series of bile acid-derived facially amphiphilic thiols have been used to cap sliver and gold nanoparticles. The self-assembling properties of these steroid-capped nanoparticles have been investigated and reported in this article.

  17. Wild 'Death Cap' Mushroom Seriously Sickens 14 in California

    Science.gov (United States)

    ... medlineplus.gov/news/fullstory_166143.html Wild 'Death Cap' Mushroom Seriously Sickens 14 in California Foraging by ... News) -- A bumper crop of deadly wild "death cap" mushrooms in northern California is likely to blame ...

  18. 'Cooling Caps' May Halt Chemo-Linked Hair Loss

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_163580.html 'Cooling Caps' May Halt Chemo-Linked Hair Loss One ... 2017 TUESDAY, Feb. 14, 2017 (HealthDay News) -- Scalp cooling caps can help breast cancer patients save their ...

  19. Highly Enhanced TMR Ratio and Δ for Double MgO-based p-MTJ Spin-Valves with Top Co2Fe6B2 Free Layer by Nanoscale-thick Iron Diffusion-barrier.

    Science.gov (United States)

    Lee, Seung-Eun; Baek, Jong-Ung; Park, Jea-Gun

    2017-09-19

    For double MgO-based p-MTJ spin-valves with a top Co2Fe6B2 free layer ex-situ annealed at 400 °C, the insertion of a nanoscale-thickness Fe diffusion barrier between the tungsten (W) capping layer and MgO capping layer improved the face-centered-cubic (f.c.c.) crystallinity of both the MgO capping layer and tunneling barrier by dramatically reducing diffusion of W atoms from the W capping layer into the MgO capping layer and tunneling barrier, thereby enhancing the TMR ratio and thermal stability (Δ). In particular, the TMR ratio was extremely sensitive to the thickness of the Fe barrier; it peaked (154%) at about 0.3 nm (the thickness of only two atomic Fe layers). The effect of the diffusion barrier originated from interface strain.

  20. Surface Morphology of Polyimide Thin Film Dip-Coated on Polyester Filament for Dielectric Layer in Fibrous Organic Field Effect Transistor

    Directory of Open Access Journals (Sweden)

    Rambausek Lina

    2014-09-01

    Full Text Available The idea of wearable electronics automatically leads to the concept of integrating electronic functions on textile substrates. Since this substrate type implies certain challenges in comparison with their rigid electronic companions, it is of utmost importance to investigate the application of materials for generating the electronic functions on the textile substrate. Only when interaction of materials and textile substrate is fully understood, the electronic function can be generated on the textile without changing the textile’s properties, being flexible or stretchable. This research deals with the optimization of the dielectric layer in a fibrous organic field effect transistor (OFET. A transistor can act as an electrical switch in a circuit. In this work, the polyimide layer was dip-coated on a copper-coated polyester filament. After thoroughly investigating the process conditions, best results with minimal thickness and roughness at full insulation could be achieved at a dip-coating speed of 50 mm/min. The polyimide solution was optimal at 15w% and the choice for the solvent NMP was made. In this paper, details on the pre-treatment methods, choice of solvent and dip-coating speed and their effect on layer morphology and thickness, electrical properties and roughness are reported. Results show that the use of polyimide as a dielectric layer in the architecture of a fibrous OFET is promising. Further research deals with the application of the semiconductor layer within the mentioned architecture, to finally build an OFET on a filament for application in smart textiles.

  1. North-Polar Martian Cap as Habitat for Elementary Life

    Science.gov (United States)

    Wallis, M. K.; Wickramasinghe, J. T.; Wickramasinghe, N. C.

    2008-09-01

    through the dirt-encrusted ice cliff [7]. Thermal conduction through the dirt crust limits sublimation of underlying ice. This allows use of the thermal wave solution: where the thermal diffusivity α combining conductivity and specific heat is taken constant and τ0 = 1.88 yr is the martian year. As in [6] we adopt a sinusoidal temperature variation and take α = 0.0001 m²/hour. Like the martian ground ice case, the transition from dirt to ice is quite sharp. The surface temperature variation at the polar cap determined from local radiative balance is largely determined by albedo, while sublimation losses from a south-facing cliff are concentrated in the summer months. For fresh frost, the albedo is close to unity but values 0.6-0.8 allow for varying amounts of exposed dirt or dust, as explored in Figure 1. This shows the integrated ice loss over one martian year (687 Earth days) using the thermal wave solution and the Clausius-Clapeyron equation for ice sublimation: for T in degrees Kelvin. The solutions in Fig. 1 indicate a 10-15cm dirt crust develops quite quickly, within a few decades, becoming thick enough to choke back the sublimation rate to under 1mm/yr, compatible with the age of the cliffs. Less steep slopes develop rather thinner crusts. The seasonal thermal wave of Equ.1 applies for depths exceeding ~5cm (two diurnal skin depths). For A of 0.6, Fig. 1 shows a 10 cm thick crust builds up in ~30yr; this thick a crust may plausibly be maintained against weathering processes. If A10 cm within a few years and the self-sealing (deposition) and flow-retarding (adsorption/desorption) properties become significant in the thicker and hotter crust [5]. For A>0.7, a 5 cm crust cuts the sublimation rate to 10 m and gives a functional fit Ψ = 1.5 x 10-12 Δ-3.1 / km2.yr from Δ = 10 m to 100 m. (3) The volume integral of the excavated mass equates to an average `gardening' rate ~1 cm / Myr, dominated by the smallest craters ~ 0.3m deep. The craters are sparse on a Myr

  2. Identification of autotoxic compounds in fibrous roots of Rehmannia (Rehmannia glutinosa Libosch..

    Directory of Open Access Journals (Sweden)

    Zhen-Fang Li

    Full Text Available Rehmannia is a medicinal plant in China. Autotoxicity has been reported to be one of the major problems hindering the consecutive monoculture of Rehmannia. However, potential autotoxins produced by the fibrous roots are less known. In this study, the autotoxicity of these fibrous roots was investigated. Four groups of autotoxic compounds from the aqueous extracts of the fibrous roots were isolated and characterized. The ethyl acetate extracts of these water-soluble compounds were further analyzed and separated into five fractions. Among them, the most autotoxic fraction (Fr 3 was subjected to GC/MS analysis, resulting in 32 identified compounds. Based on literature, nine compounds were selected for testing their autotoxic effects on radicle growth. Seven out of the nine compounds were phenolic, which significantly reduced radicle growth in a concentration-dependent manner. The other two were aliphatic compounds that showed a moderate inhibition effect at three concentrations. Concentration of these compounds in soil samples was determined by HPLC. Furthermore, the autotoxic compounds were also found in the top soil of the commercially cultivated Rehmannia fields. It appears that a close link exists between the autotoxic effects on the seedlings and the compounds extracted from fibrous roots of Rehmannia.

  3. Shear-induced fibrous structure formation from a pectin/SPI blend

    NARCIS (Netherlands)

    Dekkers, Birgit L.; Nikiforidis, Costas; Goot, van der Atze Jan

    2016-01-01

    Well-defined shear flow can be applied to create fibrous, anisotropic samples from biopolymers when present at sufficiently high dry matter contents. Anisotropic biopolymer structures are of high interest especially when made from plant-based polymer blends due to novel food applications, like me

  4. Fibrous dysplasia of the rib presenting as a huge chest wall tumor: report of a case.

    Science.gov (United States)

    Chang, B S; Lee, S C; Harn, H J

    1994-07-01

    Fibrous dysplasia of the rib is not uncommon, but is rarely demonstrated as a huge chest wall mass with severe clinical symptoms. A 59-year-old patient, presenting with a huge, rapidly expanding chest wall tumor compressing the lung, liver and heart accompanied by chest pain and dyspnea, is reported. The tumor was success-fully excised by local radical resection.

  5. A novel apparatus for countercurrent sorption separation processes using fibrous sorbents

    NARCIS (Netherlands)

    Diederen, A.M.; Zee, G. van; Veenman, A.W.; Graauw, J. de

    1998-01-01

    This paper discusses a technical feasibility study on continuous countercurrent sorption equipment using mechanically transported fibrous sorbent materials such as fiber beds and open-cell foam. A pilot unit was developed and tested and the apparatus performed adequately. Under the conditions applie

  6. Meningeal solitary fibrous tumor: report of a case and literature review.

    Science.gov (United States)

    Deniz, Kemal; Kontas, Olgun; Tucer, Bulent; Kurtsoy, Ali

    2005-01-01

    Solitary fibrous tumor is a rare neoplasm that most often involves the pleura. The increasing numbers of this neoplasm have also been reported to date in extrapleural sites. We report a case of a twenty-four-year-old female with right frontal mass. Histologically, the tumor composed of spindle cell proliferation. Tumor cells were found to be positive for CD34 and CD117 with immunohistochemical studies. Ten months follow-up was uneventful. Seventy seven cases of meningeal solitary fibrous tumor from the literature are analysed and pathological, immunohistochemical and clinical features are discussed. Solitary fibrous tumor has a slight female predominance, with a male to female ratio of 1:1.5. Age distribution is similar to meningioma ranging from 7-81 years. Approximately 23% of cases originate in the spine which is the most common meningeal location. Histopathologic examination shows uniform spindle cell proliferation with various amount of collagen. CD34-positivity usually allows discrimination from schwannomas, meningiomas and hemangiopericytomas. A differential diagnosis is important because most of the solitary fibrous tumors usually behave in a benign fashion. In this study, we also showed CD117 (Kit) expression in a case of meningeal SFT. CD117-positivity can be a good strategy for treatment in malignant and recurrent cases. Further investigations are necessary for therapeutic implication of CD117-positivity in SFT.

  7. Three dimensional web-like fibrous CuInS{sub 2} film

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Hyun [School of Mechanical Engineering, Korea University, Seoul 136-713 (Korea, Republic of); Kim, Min-woo [School of Mechanical Engineering, Korea University, Seoul 136-713 (Korea, Republic of); Green School, Korea University, Seoul, 136-713 (Korea, Republic of); Kim, Hayong [School of Mechanical Engineering, Korea University, Seoul 136-713 (Korea, Republic of); Al-Deyab, Salem S. [Petrochemicals Research Chair, Dept. of Chem., King Saud University, Riyadh 11451 (Saudi Arabia); James, Scott C. [Depts of Geology and Mechanical Engineering, Baylor University, Waco TX 76798-2534 (United States); Ahn, SeJin, E-mail: swisstel@kier.re.kr [Photovoltaic Laboratory, Korea Institute of Energy Research, 71-2 Jangdong, YuseongGu, DaeJeon 305-543 (Korea, Republic of); Yoon, Sam S., E-mail: skyoon@korea.ac.kr [School of Mechanical Engineering, Korea University, Seoul 136-713 (Korea, Republic of)

    2015-10-01

    Graphical abstract: - Highlights: • Electrospun nanofibers were used to construct a 3D CuInS{sub 2} solar cell with enhanced surface area. • SEM images showed the 3D web-like, fibrous structure of the film. • The surface area had nearly doubled after incorporating the 3D nanostructure. - Abstract: To ensure effective collection of photo-generated minority electrons in a CuInS{sub 2} thin film solar cell, a three-dimensional nanostructure was constructed by electrospinning a copper-indium solution precursor onto a molybdenum substrate. The electrospun nanofibers adhered onto the underlying layers before undergoing sulfurization at 500 °C to produce a three-dimensional web-like fibrous CuInS{sub 2} film. This fibrous film was characterized by scanning electron microscopy, X-ray diffraction, and Auger electron spectroscopy, thereby characterizing the 3D fibrous nanostructure of the CuInS{sub 2} film. This 3D structure could lead to next-generation solar cells optimized for maximal charge separation to enhance photovoltaic efficiency of solution-processed thin film solar cells.

  8. Hydrogen peroxide production from fibrous pectic cellulose analogs and effect on dermal fibroblasts

    Science.gov (United States)

    Naturally derived products with folklore remedies have in recent years been reconsidered for their benefit to wound healing i.e., honey’s application to chronic wound dressing products. Similarly, we have undertaken an evaluation of Fibrous pectin-cellulose (FPC) (cellulose blended with primary cel...

  9. Solitary fibrous tumor of the greater omentum mimicking an ovarian tumor in a young woman

    Directory of Open Access Journals (Sweden)

    Elisabet Rodriguez Tarrega

    2016-08-01

    Full Text Available We report a case of solitary fibrous tumor (SFT of greater omentum in a young woman. SFT arising from the greater omentum can mimic a gynecologic neoplasm. SFTs are generally benign but some of them are malignant and have uncertain prognosis. An adequate follow-up is essential in these patients.

  10. Fibrous tumours in children: imaging features of a heterogeneous group of disorders

    Energy Technology Data Exchange (ETDEWEB)

    Eich, G.F.; Hoeffel, J.C.; Tschaeppeler, H.; Gassner, I.; Willi, U.V. [Division of Diagnostic Imaging and Radiology, The University Children`s Hospital, Steinwiesstrasse 75, CH-8032 Zurich (Switzerland)

    1998-07-01

    Background. Fibrous tumours are predominantly soft tissue lesions which are relatively frequent in childhood but are little known. Imaging is often used in the evaluation of these tumours but their characteristics, particularly on US or MRI, have not been studied systematically. Objectives. To provide an overview of the clinical and imaging features of the different disorders, and to correlate them with the currently used classification schemes. Material and methods. Twenty-five patients with fibrous tumours were evaluated retrospectively. Clinical histories were studied for the histopathological diagnosis, age, signs and symptoms at presentation, mode of therapy and follow-up where available. Imaging findings were analysed for the following variables: number, location, size, margin and architecture of soft tissue and/or visceral lesions and the presence and pattern of osseous involvement. Comparison with the available literature was performed. Results. The following tumour types were encountered: desmoid fibromatosis (n = 9), myofibromatosis (n = 7), fibromatosis colli (n = 2), congenital-infantile fibrosarcoma (n = 2), adult-type fibrosarcoma (n = 2), fibrous hamartoma of infancy (n = 1), angiofibroma (n = 1) and hyaline fibromatosis (n = 1). Conclusions. While some tumours were non-specific in their clinical and radiological manifestation, others such as myofibromatosis, fibromatosis colli, fibrous hamartoma of infancy and angiofibroma exhibited a characteristic pattern which allowed a diagnosis to be made even without histology. (orig.) With 10 figs., 1 tab., 20 refs.

  11. Estimating the Sabine absorption coefficient of fibrous materials for various backing conditions

    DEFF Research Database (Denmark)

    Jeong, Cheol-Ho

    2017-01-01

    conditions by extracting the air flow resistivity of the test specimen and the frequency-dependent effect of the chamber on the measured absorption coefficients. Two homogeneous fibrous absorbers are measured for experimental validation, showing good agreements between the predictions and measurements...

  12. 3D multi-layered fibrous cellulose structure using an electrohydrodynamic process for tissue engineering.

    Science.gov (United States)

    Kim, Minseong; Kim, GeunHyung

    2015-11-01

    Micro/nanofibrous structures have been applied widely in various tissue-engineering applications because the topological structures are similar to the extracellular matrix (ECM), which encourages a high degree of cell adhesion and growth. However, it has been difficult to produce a three-dimensional (3D) fibrous structure using controllable macro-pores. Recently, cellulose has been considered a high-potential natural-origin biomaterial, but its use in 3D biomedical structures has been limited due to its narrow processing window. Here, we suggest a new 3D cellulose scaffold consisting of multi-layered struts made of submicron-sized entangled fibers that were fabricated using an electrohydrodynamic direct jet (EHDJ) process that is spin-printing. By optimizing processing conditions (electric field strength, cellulose feeding rate, and distance between nozzle and target), we can achieve a multi-layered cellulose structure consisting of the cylindrically entangled cellulose fibers. To compare the properties of the fabricated 3D cellulose structure, we used a PCL fibrous scaffold, which has a similar fibrous morphology and pore geometry, as a control. The physical and in vitro biocompatibilities of both fibrous scaffolds were assessed using human dermal fibroblasts, and the cellulose structure showed higher cell adhesion and metabolic activities compared with the control. These results suggest the EHDJ process to be an effective fabricating tool for tissue engineering and the cellulose scaffold has high potential as a tissue regenerative material.

  13. Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation

    Directory of Open Access Journals (Sweden)

    Jingjia Han

    2016-05-01

    Full Text Available Enhancing the maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs will facilitate their applications in disease modeling and drug discovery. Previous studies suggest that cell alignment could enhance hPSC-CM maturation; however, the robustness of this approach has not been well investigated. To this end, we examined if the anisotropic orientation of hPSC-CMs imposed by the underlying aligned fibers within a 3D microenvironment could improve the maturation of hPSC-CMs. Enriched hPSC-CMs were cultured for two weeks on Matrigel-coated anisotropic (aligned and isotropic (random polycaprolactone (PCL fibrous scaffolds, as well as tissue culture polystyrenes (TCPs as a control. As expected, hPSC-CMs grown on the two types of fibrous scaffolds exhibited anisotropic and isotropic orientations, respectively. Similar to cells on TCPs, hPSC-CMs cultured on these scaffolds expressed CM-associated proteins and were pharmacologically responsive to adrenergic receptor agonists, a muscarinic agonist, and a gap junction uncoupler in a dose-dependent manner. Although hPSC-CMs grown on anisotropic fibrous scaffolds displayed the highest expression of genes encoding a number of sarcomere proteins, calcium handling proteins and ion channels, their calcium transient kinetics were slower than cells grown on TCPs. These results suggest that electrospun anisotropic fibrous scaffolds, as a single method, have limited effect on improving the maturation of hPSC-CMs.

  14. Fibrous scaffolds made by co-electrospinning soluble eggshell membrane protein with biodegradable synthetic polymers.

    Science.gov (United States)

    Xiong, Xi; Li, Qiang; Lu, Jian-Wei; Guo, Zhao-Xia; Sun, Zhao-Hui; Yu, Jian

    2012-01-01

    Soluble eggshell membrane protein (SEP), isolated from natural eggshell membrane, was co-electrospun with biodegradable synthetic polymers poly(propylene carbonate) (PPC) and poly(lactic acid) (PLA) in various proportions from 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) solutions in order to prepare fibrous scaffolds having simultaneously good mechanical properties and biocompatibility. The fiber morphology was observed by field emission scanning electron microscopy, showing uniform fibers with diameter of 1.2-1.0 and 1.3-0.7 um for PPC/SEP and PLA/SEP blend fibers, respectively. Transmission electron microscopy observation shows that the blend fibers have domain-matrix phase morphology with fiber-like SEP domains in the PPC or PLA matrix, indicating the occurrence of phase separation, although interaction exists between PPC (or PLA) and SEP, as revealed by attenuated total reflectance Fourier transform infrared spectroscopy. The mechanical properties were evaluated by uniaxial tensile tests and showed that both the tensile strength and elongation at break increase with increasing incorporation of PPC (or PLA). The surface composition was investigated by X-ray photoelectron spectroscopy and SEP was found on the fiber surfaces, and as a result the surfaces of the fibrous scaffolds are superhydrophilic. NIH3T3 cell culture tests demonstrate that the PPC/SEP and PLA/SEP blend fibrous scaffolds have a much improved biocompatibility compared to pure PPC or PLA fibrous scaffolds.

  15. Controlled Smart Anisotropic Unidirectional Spreading of Droplet on a Fibrous Surface.

    Science.gov (United States)

    Zhang, Miaoxin; Wang, Lei; Hou, Yongping; Shi, Weiwei; Feng, Shile; Zheng, Yongmei

    2015-09-09

    Smart anisotropic-unidirectional spreading is displayed on a wettable-gradient-aligned fibrous surface due to a synergetic directing effect from the aligned structure and the ratio of hydrophilic components. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Osteoarthritis of the hip in fibrous dysplasia of the proximal femur.

    Science.gov (United States)

    Kim, H-S; Im, S B; Han, I

    2015-07-01

    Deformity of the proximal femur in fibrous dysplasia leads to deviation of the mechanical axis of the hip, which may lead to the development of secondary osteoarthritis (OA). This study investigated the prevalence and predisposing factors for the development of OA in patients with fibrous dysplasia of the proximal femur. We reviewed the records of 209 patients from our institutional database with fibrous dysplasia of the proximal femur, investigating possible predisposing factors including patient demographics, the extent of the coxa vara deformity, the presence of peri-articular disease, and the overall burden of skeletal disease. Of the 209 patients, 24 (12%) had radiological evidence of OA in the ipsilateral hip. The prevalence was significantly higher in patients with polyostotic fibrous dysplasia compared with those with monostotic disease (p dysplasia have a high risk of developing secondary OA of the hips. This risk is higher in patients with peri-articular disease, and those with a more severe deformity of proximal femur. ©2015 The British Editorial Society of Bone & Joint Surgery.

  17. CARBONIZED FIBROUS RESIN AS A NEW SORBENT FOR SAMPLING POLYCYCLIC AROMATIC HYDROCARBONS (PAHS) IN AMBIENT AIR

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A new sampling method of ambient air analysis using carbonized fibrous resin as asorbent for polycyclic aromatic hydrocarbons (PAHs) was reported.The physical and chemical properties of the carbonized fibrous resins were measured. Thesample pretreatment with ultrasonic extraction and subsequent clean-up ehition through a silica gelcolumn was optimized. The suitable ultrasonic extraction conditions were selected as follows: resinweight was 1.5 g, ultrasonic extraction time 20 min, volume of extraction solvent 100 mi andextraction operation times 2~3. The concentrated extractable organic matter was submitted to nextstep of clean-up procedure of adsorption chromatography on silica gel column/n-hexane and amixture of dichloromethene:n-hexane solution 2:3 (v/v). The PAHs fractions in the real samplesfrom Changzhou, China were particularly analyzed using GC-MS data system and the data of massspectra, retention times and scan numbers of the real samples were compared with that of thestandards of 16 PAHs listed by the US EPA as "priority pollutants" of the environment. Theanalysis of the real samples indicates that the carbonized fibrous resin is a good sorbent. Thepretreatment of samples of ambient air with carbonized fibrous resin as a sorbent for P,AHs isproved to be reliable and might be used for the procedure of the determination of PAHs inatmospheric environment.

  18. Maxillary fibrous dysplasia associated with McCune-Albright syndrome. A case study

    Directory of Open Access Journals (Sweden)

    Wójcik Sylwia

    2016-01-01

    Full Text Available McCune Albright syndrome (MCA is a rare complication of genetic origin. The authors present a case study of a patient with MCA diagnosed with multifocal fibrous dysplasia in his limb and craniofacial bones. The symptoms of the disease in the patient’s facial and oral tissue and the treatment administered have been described.

  19. Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?

    Directory of Open Access Journals (Sweden)

    Abhay Gundgurthi

    2013-01-01

    Full Text Available Polyostotic fibrous dysplasia is a rare non-inheritable genetic disease due to mutation in GNAS gene. Here we present two adults who were accidentally detected lytic lesions in spine and after extensive evaluation for malignancies; was diagnosed on biopsy. Current concept of the disease and management is discussed.

  20. Maxillary fibrous dysplasia associated with McCune-Albright syndrome. A case study.

    Science.gov (United States)

    Wójcik, Sylwia; Koszowski, Rafał; Drozdowska, Bogna; Śmieszek-Wilczewska, Joanna; Raczkowska-Siostrzonek, Agnieszka

    2016-01-01

    McCune Albright syndrome (MCA) is a rare complication of genetic origin. The authors present a case study of a patient with MCA diagnosed with multifocal fibrous dysplasia in his limb and craniofacial bones. The symptoms of the disease in the patient's facial and oral tissue and the treatment administered have been described.

  1. Maxillary fibrous dysplasia associated with McCune-Albright syndrome. A case study

    OpenAIRE

    Wójcik Sylwia; Koszowski Rafał; Drozdowska Bogna; Śmieszek-Wilczewska Joanna; Raczkowska-Siostrzonek Agnieszka

    2016-01-01

    McCune Albright syndrome (MCA) is a rare complication of genetic origin. The authors present a case study of a patient with MCA diagnosed with multifocal fibrous dysplasia in his limb and craniofacial bones. The symptoms of the disease in the patient’s facial and oral tissue and the treatment administered have been described.

  2. Continuous Degradation of Chitosan in a Convoluted Fibrous Bed Bioreactor with Immobilized Trichoderma reesei

    Institute of Scientific and Technical Information of China (English)

    WUMianbin; XIALiming; 等

    2002-01-01

    Continuous hydrolysis of chitosan was performed in a convoluted fibrous bed bioreactor (CFBB) with immobilized T. reesei. At dilution rate of 0.4d-1 and substrate concentration of 2% (mass vs. volume), the average degree of polymerization of hydrolysate can be kept at 1.25-1.35, which can be easily regulated by changing dilution rate or inlet chitosan concentration.

  3. Surgical treatment of denture-induced fibrous hyperplasia with plasma rich in growth factors.

    Science.gov (United States)

    Mozzati, Marco; Mortellaro, Carmen; Gallesio, Giorgia; Ruggiero, Tiziana; Pol, Renato

    2015-05-01

    Denture-induced fibrous hyperplasia is a fibrous connective tissue lesion that commonly occurs in oral mucosa in patients showing important alveolar ridge atrophy. In this study, we propose Plasma Rich in Growth Factors (PRGF) to overcome constrains of traditional surgical treatment. Herein, we demonstrated that PRGF represents an autologous source of growth factors able to reduce the healing time of the alveolar mucosa and the discomfort of those patients. These properties are the result of PRGF's precise biological features that result in the following: reduction of duration and intensity of postsurgical pain, acceleration of re-epithelialization of the wound, and reduction of bleeding events and of edema. In conclusion, we showed that using PRGF on patients affected by denture-induced fibrous hyperplasia allows a short healing time, thereby reducing complications and overall improving their quality of life. The aims of this study were to evaluate the influence of PRGF-ENDORET on secondary re-epithelialization in vestibuloplasty after excision of denture irritation fibrous hyperplasia, with an explorative randomized case control trial with 10 patients, 5 patients treated with PRGF and 5 patients with traditional hemostasis, and to analyze differences with simple surgery, considering postoperative rapidity of re-epithelialization, comfort, and discomfort of patients, pain, swelling, and infections.

  4. Solitary Fibrous Tumor of the Prostate Which Was Initially Misdiagnosed as Prostate Cancer

    Science.gov (United States)

    Osamu, Soma; Murasawa, Hiromi; Yoneyama, Takahiro; Koie, Takuya; Ohyama, Chikara

    2017-01-01

    Solitary fibrous tumor (SFT) of the prostate is a very rare tumor. We report a case of 65-year-old man with SFT of the prostate which was initially misdiagnosed as prostate cancer. Finally, we performed total prostatectomy and the tumor was histologically diagnosed as SFT of the prostate. The patient's clinical course has progressed favorably with no obvious recurrence 18 months postoperatively.

  5. Dedifferentiated chondrosarcoma arising in fibrous dysplasia: A case report and review of the current literature

    Directory of Open Access Journals (Sweden)

    Nicole MD Riddle

    2009-06-01

    Full Text Available Nicole MD Riddle1, Hideko Yamauchi2, Jamie T Caracciolo4, David Johnson2, G Douglas Letson2, Ardeshir Hakam1,3, Prudence V Smith1,2,3, Marilyn M Bui1,2,31Department of Pathology and Cell Biology, University of South Florida, Tampa, FL, USA; 2Department of Sarcoma, 3Department of Anatomic Pathology, 4Department of Radiology, Moffitt Cancer Center, Tampa, FL, USABackground: Fibrous dysplasia is an uncommon bone disease that has rare but clear potential for malignant transformation. The frequency is increased in polyostotic forms, McCune–Albright syndrome, Mazabraud’s syndrome, and previously irradiated sites. Rapidly progressing pain unrelated to trauma is the most concerning symptom. The early radiological features of sarcomatous transformation are moth-eaten or cystic areas of osteolysis, cortical destruction, and gradual formation of a soft tissue mass. The prognosis is unfavorable as most of the cases are in an advanced stage at the time of diagnosis.Methods: This case was diagnosed at a large cancer center in Florida. Pertinent clinical findings were obtained from chart review and inter-departmental consultation.Results: Histopathological examination revealed dysplastic lamellar bone with no osteoblastic rimming and “Chinese letter” shapes, areas composed of lobulated hyaline cartilage with mild to severe nuclear atypia, and areas of poorly differentiated cells with a spindled appearance, consistent with chondrosarcoma arising within fibrous dysplasia.Conclusions: Sarcomatous transformation of fibrous dysplasia is an uncommon occurrence, yet has significant importance for those with the disease. There may be difficulty with diagnosis given the symptoms and radiologic findings of benign fibrous dysplasia. We report a case of chondrosarcoma rising in fibrous dysplasia and review the current literature. This case is of interest due to the fact that the diagnosis of monostotic fibrous dysplasia was first made at the age of 59 and

  6. CMS end-cap yoke at the detector's assembly site.

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    The magnetic flux generated by the superconducting coil in the CMS detector is returned via an iron yoke comprising three end-cap discs at each end (end-cap yoke) and five concentric cylinders (barrel yoke). This picture shows the first of three end-cap discs (red) seen through the outer cylinder of the vacuum tank which will house the superconducting coil.

  7. 7 CFR 1714.7 - Interest rate cap.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Interest rate cap. 1714.7 Section 1714.7 Agriculture... PRE-LOAN POLICIES AND PROCEDURES FOR INSURED ELECTRIC LOANS General § 1714.7 Interest rate cap. Except... section, or both the rate disparity test for the interest rate cap and the consumer income test set forth...

  8. 20 CFR 606.22 - Application for cap.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Application for cap. 606.22 Section 606.22... Reduction § 606.22 Application for cap. (a) Application. (1) The Governor of the State shall make... a State requests a cap on tax credit reduction. The Governor is required to notify the Department on...

  9. Stress-determined nucleation sites above GaAs-capped arrays of InAs quantum dots

    Science.gov (United States)

    Latini, V.; Placidi, E.; Arciprete, F.; Tisbi, E.; Patella, F.; Magri, R.

    2016-09-01

    We studied the stress field at the surface of GaAs capping layers of variable thicknesses burying InAs quantum dot arrays using the Finite Element method to solve numerically the equations of the elastic field. The aim is to determine the stress-determined favorable sites for dot nucleation. We show that: (i) depending on the cap thickness, dot distances, and array orientation, sudden transitions in the stress-strain fields occur, leading from a vertical alignment of the dots to an anti-aligned correlation. We find that just few determined positions are favorable for dot nucleation and exclude some other sites previously indicated as favorable in the literature; (ii) the critical thicknesses at which the switch between the vertical alignment and the anti-aligned positions occurs depend on the distance between the dots in a square array and on the ratio between the two different distances if the arrays are rectangular; (iii) the transitions occur within a few nanometer range of the capping layer thickness, and the elastic field undergoes large changes in its properties before and after the transition. This behavior has been revealed by a very accurate fit of the tangential stress field using appropriate fit functions. The fit and parameter functions allow to easily reproduce the stress field in different contexts and are useful in growth simulation models. The results suggest that by properly engineering the capping layer thicknesses in the layers of a stack, it is possible to obtain different three-dimensional quantum dot lattices starting from an initial fixed dot array. Our results are in agreement with the available experimental data.

  10. Electrochemical characterization of electrospun nanocomposite polymer blend electrolyte fibrous membrane for lithium battery.

    Science.gov (United States)

    Padmaraj, O; Rao, B Nageswara; Venkateswarlu, M; Satyanarayana, N

    2015-04-23

    Novel hybrid (organic/inorganic) electrospun nanocomposite polymer blend electrolyte fibrous membranes with the composition poly(vinylidene difluoride-co-hexafluoropropylene) [P(VdF-co-HFP)]/poly(methyl methacrylate) [P(MMA)]/magnesium aluminate (MgAl2O4)/LiPF6 were prepared by the electrospinning technique. All of the prepared electrospun P(VdF-co-HFP), PMMA blend [90% P(VdF-co-HFP)/10% PMMA], and nanocomposite polymer blend [90% P(VdF-co-HFP)/10% PMMA/x wt % MgAl2O4 (x = 2, 4, 6, and 8)] fibrous membranes were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, differential scanning calorimetry, and scanning electron microscopy. The fibrous nanocomposite separator-cum-polymer blend electrolyte membranes were obtained by soaking the nanocomposite polymer blend membranes in an electrolyte solution containing 1 M LiPF6 in ethylene carbonate (EC)/diethyl carbonate (DEC) (1:1, v/v). The newly developed fibrous nanocomposite polymer blend electrolyte [90% P(VdF-co-HFP)/10% PMMA/6 wt % MgAl2O4/LiPF6] membrane showed a low crystallinity, low average fiber diameter, high thermal stability, high electrolyte uptake, high conductivity (2.60 × 10(-3) S cm(-1)) at room temperature, and good potential stability above 4.5 V. The best properties of the fibrous nanocomposite polymer blend electrolyte (NCPBE) membrane with a 6 wt % MgAl2O4 filler content was used for the fabrication of a Li/NCPBE/LiCoO2 CR 2032 coin cell. The electrochemical performance of the fabricated CR 2032 cell was evaluated at a current density of 0.1 C-rate. The fabricated CR 2032 cell lithium battery using the newly developed NCPBE membrane delivered an initial discharge capacity of 166 mAh g(-1) and a stable cycle performance.

  11. Numerical evaluation of monofil and subtle-layered evapotranspiration (ET) landfill caps

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, G.V.; Henley, M.; Valceschini, R.

    1998-01-01

    The US Department of Energy/Nevada Operations Office (DOE/NV) has identified the need to design a low-level waste (LLW) closure cap for the arid conditions at the Nevada Test Site (NTS). As a result of concerns for subsidence impacting the cover, DOE/NV redesigned the LLW cover from one containing a `hard` infiltration barrier that would likely fail, to a `soft` (ET) cover that is sufficiently deep to accommodate the hydrologic problems of subsidence. An ET cover is one that does not contain hydrologic barrier layers but relies on soil-water retention and sufficient thickness to store water until evapotranspiration (ET) can remove the moisture. Subtle layering within an ET cap using the native soil could be environmentally beneficial and cost effective.

  12. Should we geoengineer larger ice caps?

    CERN Document Server

    Haqq-Misra, Jacob

    2015-01-01

    The climate of Earth is susceptible to catastrophes that could threaten the longevity of human civilization. Geoengineering to reduce incoming solar radiation has been suggested as a way to mediate the warming effects of contemporary climate change, but a geoengineering program for thousands of years could also be used to enlarge the size of the polar ice caps and create a permanently cooler climate. Such a large ice cap state would make Earth less susceptible to climate threats and could allow human civilization to survive further into the future than otherwise possible. Intentionally extending Earth's glacial coverage will require uninterrupted commitment to this program for millenia but would ultimately reach a cooler equilibrium state where geoengineering is no longer needed. Whether or not this program is ever attempted, this concept illustrates the need to identify preference among potential climate states to ensure the long-term success of civilization.

  13. Status of the AlCap experiment

    CERN Document Server

    Litchfield, R Phillip

    2015-01-01

    The AlCap experiment is a joint project between the COMET and Mu2e collaborations. Both experiments intend to look for the lepton-flavour violating conversion $\\mu + A \\rightarrow e + A$, using tertiary muons from high-power pulsed proton beams. In these experiments the products of ordinary muon capture in the muon stopping target are an important concern, both in terms of hit rates in tracking detectors and radiation damage to equipment. The goal of the AlCap experiment is to provide precision measurements of the products of nuclear capture on Aluminium, which is the favoured target material for both COMET and Mu2e. The results will be used for optimising the design of both conversion experiments, and as input to their simulations. Data was taken in December 2013 and is currently being analysed.

  14. Greening CAP payments: a missed opportunity?

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, Alan

    2013-01-15

    At an important point in the current reform of the Common Agricultural Policy (CAP), a new IIEA policy brief by Professor Alan Matthews, one of the EU’s foremost experts on the topic, considers proposals to green direct farm payments. Professor Matthews argues that proposed greening of direct payments – the key innovation in the current round of CAP Reform – look likely to fail. While greening may survive as a concept, the likely outcome of the negotiations between Agriculture Ministers and the European Parliament will deliver little practical environmental benefit. The paper examines the rationale underpinning greening, arguing that it exists to justify the continuation of a large agricultural budget, explores reasons for the apparent failure of the proposals, and reflects on the implications for future efforts to better integrate environmental objectives into EU agriculture policy. This is the first in a series of Environment Nexus policy briefs by leading experts in the fields of agriculture, energy, climate change and water.

  15. Farmer preference for CAPS: Workshop and analysis

    OpenAIRE

    Reed, B.F.

    2012-01-01

    Analytic Hierarchy Process (AHP) is a a multi-criteria, multi-level decision-making method which breaks down complex decisions into a series of simple questions reflecting an optimal goal, objectives, and various options. This provides a structured technique for organizing and analyzing differing preferences for Conservation Agriculture Production Systems (CAPS). This presentation explains AHP and conducts a survey to collect gender-specific preference data for selected conservation agricultu...

  16. Cytocompatibility and Antibacterial Properties of Capping Materials

    OpenAIRE

    Claudio Poggio; Carla Renata Arciola; Riccardo Beltrami; Annachiara Monaco; Alberto Dagna; Marco Lombardini; Livia Visai

    2014-01-01

    The aim of this study was to evaluate and compare the antimicrobial activity and cytocompatibility of six different pulp-capping materials: Dycal (Dentsply), Calcicur (Voco), Calcimol LC (Voco), TheraCal LC (Bisco), MTA Angelus (Angelus), and Biodentine (Septodont). To evaluate antimicrobial activity, materials were challenged in vitro with Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguis in the agar disc diffusion test. Cytocompatibility of the assayed materials towa...

  17. Protein synthesis in geostimulated root caps

    Science.gov (United States)

    Feldman, L. J.

    1982-01-01

    A study is presented of the processes occurring in the root cap of corn which are requisite for the formation of root cap inhibitor and which can be triggered or modulated by both light and gravity. The results of this study indicate the importance of protein synthesis for light-induced gravitropic bending in roots. Root caps in which protein synthesis is prevented are unable to induce downward bending. This suggests that light acts by stimulating proteins which are necessary for the translation of the gravitropic stimulus into a growth response (downward bending). The turnover of protein with time was also examined in order to determine whether light acts by stimulating the synthesis of unique proteins required for downward growth. It is found that auxin in combination with light allows for the translation of the gravitropic stimulus into a growth response at least in part through the modification of protein synthesis. It is concluded that unique proteins are stimulated by light and are involved in promoting the downward growth in roots which are responding to gravity.

  18. Pulp-Capping with Mineral Trioxide Aggregate

    Directory of Open Access Journals (Sweden)

    Peycheva Kalina

    2015-11-01

    Full Text Available There are two considerations for direct pulp capping - accidental mechanical pulp exposure and exposure caused by caries. Mineral trioxide aggregate (MTA was used as pulp-capping material to preserve the vitality of the pulpal tissues. Follow-up examinations revealed that treatment was successful in preserving pulpal vitality and continued development of the tooth. On the basis of available information, it appears that MTA is the material of choice for some clinical applications. Material and methods: Cases 18 - 8 teeth with grey MTA, 10 teeth with white MTA; diagnose: Pulpitis chronica ulcerosa, Electro pulpal test (EOD - 30-35 μA, pre-clinical X-ray - without changes in the structures, follow ups for 4 years. Successful treatments: without clinical symptoms and changes in the X-rays: 5 teeth with grey MTA, 8 teeth with white MTA for period of 4 years. Unsuccessful treatments: Clinical symptoms and sometimes changes in the X-ray: 3 with grey MTA, 2 with white MTA. MTA is an appropriate material for pulp-capping and follow-up examinations revealed that the treatment was successful in preserving pulpal vitality.

  19. Analysis list: Cap-H2 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Cap-H2 Cell line + dm3 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/target/Cap-H2....1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/target/Cap-H2.5.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/target/Cap...-H2.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/colo/Cap-H2.Cell_line.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/colo/Cell_line.gml ...

  20. The morphology of corneal cap and its relation to refractive outcomes in femtosecond laser small incision lenticule extraction (SMILE with anterior segment optical coherence tomography observation.

    Directory of Open Access Journals (Sweden)

    Jing Zhao

    Full Text Available PURPOSE: To investigate the morphology of corneal caps in femtosecond laser small incision lenticule extraction (SMILE and its relation to the refractive outcomes. METHODS: A prospective study of fifty-four corneal caps created with VisuMax femtosecond laser were examined using an Fourier-domain optical coherence tomography at 1 day, 1 week, 1 month and 6 months after SMILE. The cap thickness at nine points on each of the four meridians (0°, 45°, 90°, 135° and the diameter were measured. Cap morphology, changes over time and its correlation with refractive outcomes were assessed. RESULTS: The mean achieved central cap thickness were (108.74±5.06 µm at 6 months and (107.32±4.81 µm at 1 month postoperatively, significantly thinner than that at 1 day (110.81±7.95 µm and 1 week (109.58±7.48 µm (P<0.05. The mean diameter on 0° meridian was (7.61±0.07 mm, significantly larger than that on 90° meridian (7.57±0.06 mm (P = 0.001. Cap morphology showed good regularity, except that the differences of points in two pairs were significant at 1 day postoperatively. The uniformity was consistent over time and the central cap thickness was thinner than those in the paracentral and peripheral areas. The refractive outcomes stabilized within 1 month. Uncorrected distance visual acuity (UDVA was correlated to the central cap thickness at 1 day and 1 week (both rs  = 0.33, p<0.05. The uniformity index was correlated with UDVA (rs  = 0.34, p<0.05 and corrected distance visual acuity (rs  = 0.32, p<0.05 at 1 week postoperatively. CONCLUSIONS: Corneal caps of SMILE are predictable with good reproducibility, regularity and uniformity. Cap morphology might have a mild effect on refractive outcomes in the early stage. Further study should focus on the impact on the visual quality.