Characterization of the adenoassociated virus Rep protein complex formed on the viral origin of DNA replication

International Nuclear Information System (INIS)

Li Zengi; Brister, J. Rodney; Im, Dong-Soo; Muzyczka, Nicholas

2003-01-01

Interaction between the adenoassociated virus (AAV) replication proteins, Rep68 and 78, and the viral terminal repeats (TRs) is mediated by a DNA sequence termed the Rep-binding element (RBE). This element is necessary for Rep-mediated unwinding of duplex DNA substrates, directs Rep catalyzed cleavage of the AAV origin of DNA replication, and is required for viral transcription and proviral integration. Six discrete Rep complexes with the AAV TR substrates have been observed in vitro, and cross-linking studies suggest these complexes contain one to six molecules of Rep. However, the functional relationship between Rep oligomerization and biochemical activity is unclear. Here we have characterized Rep complexes that form on the AAV TR. Both Rep68 and Rep78 appear to form the same six complexes with the AAV TR, and ATP seems to stimulate formation of specific, higher order complexes. When the sizes of these Rep complexes were estimated on native polyacrylamide gels, the four slower migrating complexes were larger than predicted by an amount equivalent to one or two TRs. To resolve this discrepancy, the molar ratio of protein and DNA was calculated for the three largest complexes. Data from these experiments indicated that the larger complexes included multiple TRs in addition to multiple Rep molecules and that the Rep-to-TR ratio was approximately 2. The two largest complexes were also associated with increased Rep-mediated, origin cleavage activity. Finally, we characterized a second, Rep-mediated cleavage event that occurs adjacent to the normal nicking site, but on the opposite strand. This second site nicking event effectively results in double-stranded DNA cleavage at the normal nicking site

Identification and Characterization of the Novel p97 co-factors, Rep8 and ASPL

DEFF Research Database (Denmark)

Klausen, Louise Kjær

to the ER membrane with the UBX domain situated in the cytosol. Mouse Rep8 is highly tissue-specific and abundant in gonads. In tests, Rep8 is expressed in post-meiotic round spermatids, whereas in ovaries Rep8 is expressed in granulosa cells. Additional precipitation experiments revealed that Rep8......The highly conserved and ubiquitin-specific AAA ATPase p97 acts on ubiquitylated substrates in diverse cellular mechanisms such as chromatin-associated degradation, fusion of homotypic membranes and ER-associated degradation. Different p97 cofactors associate with the ATPase, thereby constituting...... that ASPL localizes to the ER membrane and in vitro ASPL leads to disassembly of the p97 hexameric ATPase. Rep8 was found to interact with p97 both in vitro and in vivo, and the binding was mediated through the N-domain of p97 and the UBX domain of Rep8. Localization studies showed that Rep8 localizes...

3D printing with RepRap cookbook

CERN Document Server

Salinas, Richard

2014-01-01

A systematic guide consisting of over 100 recipes which focus on helping you understand the process of 3D printing using RepRap machines. The book aims at providing professionals with a series of working recipes to help make their fuzzy notions into real, saleable projects/objects using 3D printing technology. This book is for novice designers and artists who own a RepRap-based 3D printer, have fundamental knowledge of its working, and who desire to gain better mastery of the printing process. For the more experienced user, it will provide a handy visual resource, with side-by-side comparisons

Catalytic Copolymerization of Ethene and Carbon Monoxide on Nickel Complexes.

Science.gov (United States)

Domhöver, Bernd; Kläui, Wolfgang; Kremer-Aach, Andreas; Bell, Ralf; Mootz, Dietrich

1998-11-16

Can palladium be replaced by nickel? For the industrial copolymerization of carbon monoxide and ethene a palladium catalyst is used which cannot be recovered-a cheaper procedure would be desirable. The presented complex 1 is the first structurally characterized nickel compound which does not polymerize ethene but a mixture from carbon monoxide and ethene unter mild conditions to give a perfectly alternating polyketone. © 1998 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Regulation and drive system for high rep-rate magnetic-pulse compressors

International Nuclear Information System (INIS)

Birx, D.L.; Cook, E.G.; Hawkins, S.; Meyers, A.; Reginato, L.L.; Schmidt, J.A.; Smith, M.W.

1982-01-01

The essentially unlimited rep-rate capability of non-linear magnetic systems has imposed strict requirements on the drive system which initiates the pulse compression. An order of magnitude increase in the rep-rates achieved by the Advanced Test Accelerator (ATA) gas blown system is not difficult to achieve in the magnetic compressor. The added requirement of having a high degree of regulation at the higher rep-rates places strict requirements on the triggerable switch for charging and de-Queing. A novel feedback technique which applies the proper bias to a magnetic core by comparing a reference voltage to the charging voltage eases considerably the regulation required to achieve low jitter in magnetic compression. The performance of the high rep-rate charging and regulation systems will be described in the following pages

Deformable M-Reps for 3D Medical Image Segmentation

Science.gov (United States)

Pizer, Stephen M.; Fletcher, P. Thomas; Joshi, Sarang; Thall, Andrew; Chen, James Z.; Fridman, Yonatan; Fritsch, Daniel S.; Gash, Graham; Glotzer, John M.; Jiroutek, Michael R.; Lu, Conglin; Muller, Keith E.; Tracton, Gregg; Yushkevich, Paul; Chaney, Edward L.

2013-01-01

M-reps (formerly called DSLs) are a multiscale medial means for modeling and rendering 3D solid geometry. They are particularly well suited to model anatomic objects and in particular to capture prior geometric information effectively in deformable models segmentation approaches. The representation is based on figural models, which define objects at coarse scale by a hierarchy of figures – each figure generally a slab representing a solid region and its boundary simultaneously. This paper focuses on the use of single figure models to segment objects of relatively simple structure. A single figure is a sheet of medial atoms, which is interpolated from the model formed by a net, i.e., a mesh or chain, of medial atoms (hence the name m-reps), each atom modeling a solid region via not only a position and a width but also a local figural frame giving figural directions and an object angle between opposing, corresponding positions on the boundary implied by the m-rep. The special capability of an m-rep is to provide spatial and orientational correspondence between an object in two different states of deformation. This ability is central to effective measurement of both geometric typicality and geometry to image match, the two terms of the objective function optimized in segmentation by deformable models. The other ability of m-reps central to effective segmentation is their ability to support segmentation at multiple levels of scale, with successively finer precision. Objects modeled by single figures are segmented first by a similarity transform augmented by object elongation, then by adjustment of each medial atom, and finally by displacing a dense sampling of the m-rep implied boundary. While these models and approaches also exist in 2D, we focus on 3D objects. The segmentation of the kidney from CT and the hippocampus from MRI serve as the major examples in this paper. The accuracy of segmentation as compared to manual, slice-by-slice segmentation is reported. PMID

Molecular characterization of Salmonella isolates by REP-PCR and RAPD analysis.

Science.gov (United States)

Albufera, U; Bhugaloo-Vial, P; Issack, M I; Jaufeerally-Fakim, Y

2009-05-01

Eighteen Salmonella isolates from both human and food (non-human) sources (fish, meat, and poultry) were characterized using conventional culture methods, biochemical, serological, and molecular analyses. REP-PCR and RAPD produced DNA profiles for differentiation purposes. Enterobacterial repetitive intergenic consensus (ERIC), repetitive extragenic palindronic (REP) and BOXAIR primers were selected for REP-PCR and two arbitrary primers, namely OPP-16 and OPS-11 were used for RAPD to generate DNA fingerprints from the Salmonella isolates. REP-PCR method showed greater discriminatory power in differentiating closely related strains of the related strains of Salmonella and produced more complex banding patterns as compared with RAPD. A dendogram was constructed with both sets of profiles using SPSS Version 13.0 computer software and showed that most human isolates were separately clustered from the non-human isolates. Two of the human isolates were closely related to some of the non-human isolates. A good correlation was also observed between the serogrouping of the O antigen and the molecular profiles obtained from REP-PCR and RAPD data of the Salmonella isolates. The results of a principal coordinate analysis (PCA) corresponded to the clustering in the dendrogram.

Expression, purification, characterization and subcellular localization of the goose parvovirus rep1 protein.

Science.gov (United States)

Chen, Zongyan; Li, Chuanfeng; Peng, Gaojing; Liu, Guangqing

2013-07-01

The goose parvovirus (GPV) Rep1 protein is both essential for viral replication and a potential target for GPV diagnosis, but its protein characterization and intracellular localization is not clear. We constructed a recombinant plasmid, pET28a/GPV-Rep1, and expressed the Rep1 gene in BL21 (DE3) Escherichia coli. A protein approximately 75 kDa in size was obtained from lysates of E. coli cells expressing the recombinant plasmid. SDS-PAGE analysis showed that after induction with 0.6 mM isopropyl β-D-thiogalactosidase (IPTG) at 30°C for 5 h, the Rep1 protein was highly overexpressed. Two methods used to purify proteins, a salinity-gradient elution and Ni-NTA affinity chromatography, were performed. The amount of Rep1 protein obtained by Ni-NTA affinity chromatography was 41.23 mg, while 119.9 mg of Rep1 protein was obtained by a salinity-gradient elution from a 1 L E. coli BL21 (DE3) culture. An immunogenicity analysis showed that the protein could significantly elicit a specific antibody response in immunized goslings compared to control groups. Antibody titers peaked to 1:5120 (optical density (OD) 450 = 3.9) on day 28 after immunization but had mean titers of 1:10,240 (OD450 = 4.2) in gosling groups immunized with a commercially available GPV-attenuated vaccine strain. Experiments examining subcellular localization showed that the Rep1 protein appeared to associate predominantly with the nuclear membrane, especially during later times of infection. This work provides a basis for biochemical and structural studies on the GPV Rep1 protein.

Manganese(III) Formate: A Three-Dimensional Framework That Traps Carbon Dioxide Molecules.

Science.gov (United States)

Cornia, Andrea; Caneschi, Andrea; Dapporto, Paolo; Fabretti, Antonio C; Gatteschi, Dante; Malavasi, Wanda; Sangregorio, Claudio; Sessoli, Roberta

1999-06-14

Carbon dioxide, formic acid, and water molecules are trapped in the crystal lattice of manganese(III) formate (see 1), which was obtained by reducing permanganate with formic acid. Each CO 2 guest molecule exhibits four C-H⋅⋅⋅O-C-O interactions with the three-dimensional host framework of Mn(HCOO) 3 units. Compound 1 undergoes an antiferromagnetic phase transition at 27 K. © 1999 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

O ethos do repórter de TV da Rede Globo

Directory of Open Access Journals (Sweden)

Marcia Benetti

2017-05-01

Full Text Available O artigo analisa os elementos instituintes das imagens de si de repórteres de televisão da Rede Globo, maior emissora do Brasil. A partir do conceito de ethos discursivo, discutimos como o discurso autorreferente afirma a identidade do jornalista e certos efeitos de verdade a respeito da reportagem. Por meio da análise do discurso de cinco entrevistas de repórteres da Rede Globo concedidas à também jornalista Fátima Bernardes, propomos que o ethos do repórter constrói-se em três dimensões: os atributos do “bom jornalista”, as características do “bom repórter” e as particularidades de pertencimento ao campo jornalístico. Como articuladores do ethos, os valores morais e os aspectos relacionados às rotinas profissionais convocam a audiência a se conectar com certas definições sobre o jornalismo.

Images en mouvement stockage, repérage, indexation

CERN Document Server

Turner, James

1998-01-01

L'avènement puis la fusion des nouveaux modes de communication que sont l'informatique, les télécommunications et l'audiovisuel ont mis à la portée de tous une grande quantité d'images fixes et en mouvement dont la conservation et le repérage risquent de prendre des proportions démesurées. Le présent ouvrage veut offrir aux responsables de collection des repères pour aborder la problématique de l'indexation des images et faciliter l'accès des usagers à ces images.

Intracellular route and biological activity of exogenously delivered Rep proteins from the adeno-associated virus type 2

International Nuclear Information System (INIS)

Awedikian, Rafi; Francois, Achille; Guilbaud, Mickael; Moullier, Philippe; Salvetti, Anna

2005-01-01

The two large Rep proteins, Rep78 and Rep68, from the adeno-associated virus type 2 (AAV-2) are required for AAV-2 DNA replication, site-specific integration, and for the regulation of viral gene expression. The study of their activities is dependent on the ability to deliver these proteins to the cells in a time and dose-dependent manner. We evaluated the ability of a protein transduction domain (PTD) derived from the human immunodeficiency virus 1 (HIV-1) TAT protein to drive the cellular internalization of exogenously delivered PTD-fused Rep68 proteins. This analysis unexpectedly revealed that recombinant Rep68 alone, in the absence of any PTD, could be endocytosed by the cells. Rep68 as the chimeric TAT-Rep68 proteins were internalized through endocytosis in clathrin-coated vesicles and retained in late endosomes/lysosomes with no detectable nuclear localization. In the presence of adenovirus, the Rep proteins could translocate into the nucleus where they displayed a biological activity. These findings support recent reports on the mechanism of entry of TAT-fused proteins and also revealed a new property of Rep68

Typing of avian pathogenic Escherichia coli strains by REP-PCR Tipificação de amostras aviárias patogênicas de Escherichia coli pela REP-PCR

Directory of Open Access Journals (Sweden)

Marcelo Brocchi

2006-06-01

Full Text Available In the present study the repetitive extragenic palindromic (REP polymerase chain reaction (PCR technique was used to establish the clonal variability of 49 avian Escherichia coli (APEC strains isolated from different outbreak cases of septicemia (n=24, swollen head syndrome (n=14 and omphalitis (n=11. Thirty commensal strains isolated from poultry with no signs of these illnesses were used as control strains. The purified DNA of these strains produced electrophoretic profiles ranging from 0 to 15 bands with molecular sizes varying from 100 bp to 6.1 kb, allowing the grouping of the 79 strains into a dendrogram containing 49 REP-types. Although REP-PCR showed good discriminating power it was not able to group the strains either into specific pathogenic classes or to differentiate between pathogenic and non-pathogenic strains. On the contrary, we recently demonstrated that other techniques such as ERIC-PCR and isoenzyme profiles are appropriate to discriminate between commensal and APEC strains and also to group these strains into specific pathogenic classes. In conclusion, REP-PCR seems to be a technique neither efficient nor universal for APEC strains discrimination. However, the population clonal structure obtained with the use of REP-PCR must not be ignored particularly if one takes into account that the APEC pathogenic mechanisms are not completely understood yet.A técnica de REP (Repetitive extragenic palindrome-PCR foi utilizada para avaliar a variabilidade genética de 49 amostras de Escherichia coli patogênicas para aves (APEC, isoladas de aves de corte (frangos em diferentes surtos de septicemia (n=24, síndrome da cabeça inchada (n=14 e onfalite (n=11. Trinta amostras comensais, isoladas de frangos sem sinais de doença, foram utilizadas como controle. A análise do perfil eletroforético obtido por reação de REP-PCR utilizando DNA purificado das amostras evidenciou a amplificação de 0 a 15 bandas de DNA com pesos moleculares

Mailis Reips : Prezhde vsego neobhodimo natshat / Mailis Reps

Index Scriptorium Estoniae

Reps, Mailis, 1975-

2006-01-01

Haridusminister Mailis Reps kakskeelse hariduse vajalikkusest vene õppekeelega koolides, noorte keeleoskusest, eesti keele õpetamise kvaliteedist, õpetajate eesti keele oskusest, õppetöö kvaliteedist

Development of low-cost open source 3D gel printer "RepRap SWIM-ER"

Science.gov (United States)

Sato, Kei; Basher, Samiul; Ota, Takafumi; Tase, Taishi; Takamatsu, Kyuichiro; Saito, Azusa; Khosla, Ajit; Kawakami, Masaru; Furuawa, Hidemitsu

2017-04-01

Gels are soft and wet materials having low friction, good biocompatibility, and material permeability. It is expected that gel materials will be used as new kinds of industrial materials in the engineering and medical applications. But it cannot build a complicated shape. Soft & Wet Matter Engineering Laboratory developed a 3D gel Printer "SWIM-ER", has enabled modeling of complex shapes of the gel. However, this is expensive. Therefore not all of the gel researchers and the companies have such a device. To solve this problem, we manufacture a low-cost open-source 3D gel printer "RepRap SWIM-ER" from the RepRap. We made the components required to manufacture the "RepRap SWIM-ER" from the 3D printer and chose a light source. In addition, we produced the P-DN gel for RepRap SWIM-ER and conducted the molding test to confirm whether RepRap SWIM-ER can used it.

Dithioacetals as an Entry to Titanium-Alkylidene Chemistry: A New and Efficient Carbonyl Olefination.

Science.gov (United States)

Breit, Bernhard

1998-03-02

Wittig, Horner-Wadsworth-Emmons, Julia-Lythgoe, Tebbe, Grubbs, and Petasis-when it comes to carbonyl olefinations, these names are familiar to all chemistry students. In the future, the name Takeda will probably have to be added to this list. His recent work on the formation of titanium-alkylidene species from dithioacetals has provided organic chemists with a remarkable method for carbonyl olefination that is generally applicable under neutral to Lewis acidic conditions. © 1998 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Democracia y República

OpenAIRE

Toledo, Víctor Fabio

2013-01-01

p. 33-34 En la actualidad se ha reavivado el debate en torno a los conceptos de Democracia y República. Desde el triunfo sobre el nazismo a mediados del siglo XX la democracia se ha constituido en un imperativo occidental y, a partir del derrumbe soviético, en uno cuasi universal. Sin embargo, en algunos casos —y no pocos por cierto— en el reclamo por la democratización se encontraron razones ideales para consagrar la concentración de los poderes del Estado, por paradójico que parezca. Es ...

Applications: REP-rate pulse power technology

International Nuclear Information System (INIS)

Anon.

1979-01-01

Research on the following topics is discussed: (1) REP-rate pulse power technology, (2) RTF-I, 300-J, 100-pps test facility experiments, (3) transformer development, (4) reactor system studies, (5) general conceptual design, (6) economic considerations, (7) specific reactor designs, (8) low-current density diode physics studies, and (9) plasma injected, microsecond, E-beam diodes

The Filament-specific Rep1-1 Repellent of the Phytopathogen Ustilago maydis Forms Functional Surface-active Amyloid-like Fibrils

NARCIS (Netherlands)

Teertstra, Wieke R.; van der Velden, Gisela J.; de Jong, Jan F.; Kruijtzer, John A. W.; Liskamp, Rob M. J.; Kroon-Batenburg, Loes M. J.; Muller, Wally H.; Gebbink, Martijn F. B. G.; Wosten, Han A. B.

2009-01-01

Repellents of the maize pathogen Ustilago maydis are involved in formation of hydrophobic aerial hyphae and in cellular attachment. These peptides, called Rep1-1 to Rep1-11, are encoded by the rep1 gene and result from cleavage of the precursor protein Rep1 during passage of the secretion pathway.

HYDRO-ECOLOGICAL ANALYSIS OF THE FEN SYSTEM LIEPER POSSE, EASTERN GERMANY

NARCIS (Netherlands)

VANDIGGELEN, R; GROOTJANS, AP; KEMMERS, RH; KOOIJMAN, AM; SUCCOW, M; DEVRIES, NPJ; VANWIRDUM, G; Vries, N.P.J. de; Wirdum, G. van

The Lieper Posse is a calcareous, ground water-fed fen system, situated in the end-moraine area of northeastern Germany. Nowadays the fen is partly drained and the vegetation adversely affected; hence regeneration measures are considered. Here we report a pilot survey of the actual vegetation cover

Evolution of REP diversity: a comparative study

Czech Academy of Sciences Publication Activity Database

Nunvář, Jaroslav; Lichá, I.; Schneider, Bohdan

2013-01-01

Roč. 14, č. 385 (2013) ISSN 1471-2164 R&D Projects: GA ČR GAP305/12/1801 Institutional research plan: CEZ:AV0Z50520701 Keywords : REP elements * Stenotrophomonas maltophilia * Pseudomonas fluorescens Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.041, year: 2013

Structure and Magnetic Properties of a Dodecanuclear Twisted-Ring Iron(III) Cluster.

Science.gov (United States)

Caneschi, Andrea; Cornia, Andrea; Fabretti, Antonio C; Gatteschi, Dante

1999-05-03

An unprecedented nonplanar structure characterizes the complex [Fe(OCH 3 ) 2 (dbm)] 12 (on the left in the picture), which contains the largest cyclic ferric cluster yet reported with chemically equivalent bridging units. It is made up of twelve high-spin, antiferromagnetically coupled iron(III) centers and neatly reacts with Na I or Li I templates in organic solution to give hexairon(III) coronates (right). Fe=•, O=○, NaI or LiI=• Hdbm=dibenzoylmethane. © 1999 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS

Directory of Open Access Journals (Sweden)

Alves-Ferreira Marcelo

2008-09-01

Full Text Available Abstract Background Genome survey sequences (GSS offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive regions of the genome. A more precise estimation of the nature, quantity and variability of repetitive sequences very early in a genome sequencing project is of considerable importance, as such data strongly influence the estimation of genome coverage, library quality and progress in scaffold construction. Also, the elimination of repetitive sequences from the initial assembly process is important to avoid errors and unnecessary complexity. Repetitive sequences are also of interest in a variety of other studies, for instance as molecular markers. Results We designed and implemented a straightforward pipeline called ReRep, which combines bioinformatics tools for identifying repetitive structures in a GSS dataset. In a case study, we first applied the pipeline to a set of 970 GSSs, sequenced in our laboratory from the human pathogen Leishmania braziliensis, the causative agent of leishmaniosis, an important public health problem in Brazil. We also verified the applicability of ReRep to new sequencing technologies using a set of 454-reads of an Escheria coli. The behaviour of several parameters in the algorithm is evaluated and suggestions are made for tuning of the analysis. Conclusion The ReRep approach for identification of repetitive elements in GSS datasets proved to be straightforward and efficient. Several potential repetitive sequences were found in a L. braziliensis GSS dataset generated in our laboratory, and further validated by the analysis of a more complete genomic dataset from the EMBL and Sanger Centre databases. ReRep also identified most of the E. coli K12 repeats prior to assembly in an example dataset obtained by automated sequencing using 454 technology. The parameters controlling the algorithm behaved consistently and may be tuned to the properties

The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins

DEFF Research Database (Denmark)

Madsen, Louise; Kriegenburg, Franziska; Lages Lino Vala, Andrea

2011-01-01

is a transmembrane protein that localizes to the ER membrane with its UBX domain facing the cytoplasm. Knock-down of Rep8 expression in human cells leads to a decreased association of p97 with the ER membrane and concomitantly a retarded degradation of misfolded ER-derived proteasome substrates. Thus, Rep8 tethers p......The protein known as p97 or VCP in mammals and Cdc48 in yeast is a versatile ATPase complex involved in several biological functions including membrane fusion, protein folding, and activation of membrane-bound transcription factors. In addition, p97 plays a central role in degradation of misfolded...... protein named Rep8 or Ubxd6 as a new cofactor of p97. Mouse Rep8 is highly tissue-specific and abundant in gonads. In testes, Rep8 is expressed in post-meiotic round spermatids, whereas in ovaries Rep8 is expressed in granulosa cells. Rep8 associates directly with p97 via its UBX domain. We show that Rep8...

El concepto de República en José Martí

OpenAIRE

Dr. Ibrahim Hidalgo

2015-01-01

El acercamiento a una visión martiana sobre el concepto de la república es la esencia del artículo, donde se parte del análisis de sus textos, situando el concepto de república en el centro de su pensamiento y su actuar políticos e ideológicos, que han devenido objeto de análisis y valoraciones desde diversos ángulos, perspectivas y proyecciones por autores que a lo largo del siglo XX, y en la actualidad. El elemento esencial de la concepción es el ser individualmente considerado, cuya unión ...

Obliquamente, os mitos. (República, II

Directory of Open Access Journals (Sweden)

Loraine Oliveira

2016-12-01

Full Text Available A República é um texto repleto de mitos, que ora são condenados, ora integrados à educação na cidade. No livro II a discussão mostra quais são condenáveis e quais são úteis. E o motivo dessa posição ambivalente de Platão a respeito do mito é um só: os mitos se imprimem na alma. Sendo assim, eles são formadores do caráter. O problema é que há mitos pseûdos, ou seja, falsos, mentirosos, fictícios. E há mitos que possuem um elemento de verdade e um elemento pseûdos. Mas eles jamais são completamente verdadeiros. Ora, qual a função do pseûdos, considerando que os mitos formam o caráter? Um discurso, seja ficcional, ou mítico, pode ser filosófico? Se isso for possível, o texto da República não é ele mesmo uma ficção? Um mito? Por breves apontamentos, este estudo segue essas questões.

Lipofection of purified adeno-associated virus Rep68 protein: toward a chromosome-targeting nonviral particle.

Science.gov (United States)

Lamartina, S; Roscilli, G; Rinaudo, D; Delmastro, P; Toniatti, C

1998-09-01

Adeno-associated virus (AAV) integrates very efficiently into a specific site (AAVS1) of human chromosome 19. Two elements of the AAV genome are sufficient: the inverted terminal repeats (ITRs) and the Rep78 or Rep68 protein. The incorporation of the AAV integration machinery in nonviral delivery systems is of great interest for gene therapy. We demonstrate that purified recombinant Rep68 protein is functionally active when directly delivered into human cells by using the polycationic liposome Lipofectamine, promoting the rescue-replication of a codelivered ITR-flanked cassette in adenovirus-infected cells and its site-specific integration in noninfected cells. The sequencing of cloned virus-host DNA junctions confirmed that lipofected Rep68 protein triggers site-specific integration at the same sites in chromosome 19 already characterized in cells latently infected with AAV.

Hariduspoliitikas ilmnevad üksmeele märgid / Mailis Reps

Index Scriptorium Estoniae

Reps, Mailis, 1975-

2006-01-01

Ilmunud ka: Severnoje Poberezhje 7. juuni lk. 2, Nädaline 10. juuni lk. 2. Haridusminister Mailis Reps Res Publica ja Isamaaliidu ühisest haridusprogrammist ning juba teostumas hariduspoliitilistest eesmärkidest

The adeno-associated virus major regulatory protein Rep78-c-Jun-DNA motif complex modulates AP-1 activity

International Nuclear Information System (INIS)

Prasad, C. Krishna; Meyers, Craig; Zhan Dejin; You Hong; Chiriva-Internati, Maurizio; Mehta, Jawahar L.; Liu Yong; Hermonat, Paul L.

2003-01-01

Multiple epidemiologic studies show that adeno-associated virus (AAV) is negatively associated with cervical cancer (CX CA), a cancer which is positively associated with human papillomavirus (HPV) infection. Mechanisms for this correlation may be by Rep78's (AAV's major regulatory protein) ability to bind the HPV-16 p97 promoter DNA and inhibit transcription, to bind and interfere with the functions of the E7 oncoprotein of HPV-16, and to bind a variety of HPV-important cellular transcription factors such as Sp1 and TBP. c-Jun is another important cellular factor intimately linked to the HPV life cycle, as well as keratinocyte differentiation and skin development. Skin is the natural host tissue for both HPV and AAV. In this article it is demonstrated that Rep78 directly interacts with c-Jun, both in vitro and in vivo, as analyzed by Western blot, yeast two-hybrid cDNA, and electrophoretic mobility shift-supershift assay (EMSA supershift). Addition of anti-Rep78 antibodies inhibited the EMSA supershift. Investigating the biological implications of this interaction, Rep78 inhibited the c-Jun-dependent c-jun promoter in transient and stable chloramphenicol acetyl-transferase (CAT) assays. Rep78 also inhibited c-Jun-augmented c-jun promoter as well as the HPV-16 p97 promoter activity (also c-Jun regulated) in in vitro transcription assays in T47D nuclear extracts. Finally, the Rep78-c-Jun interaction mapped to the amino-half of Rep78. The ability of Rep78 to interact with c-Jun and down-regulate AP-1-dependent transcription suggests one more mechanism by which AAV may modulate the HPV life cycle and the carcinogenesis process

RepSox improves viability and regulates gene expression in rhesus monkey-pig interspecies cloned embryos.

Science.gov (United States)

Zhu, Hai-Ying; Jin, Long; Guo, Qing; Luo, Zhao-Bo; Li, Xiao-Chen; Zhang, Yu-Chen; Xing, Xiao-Xu; Xuan, Mei-Fu; Zhang, Guang-Lei; Luo, Qi-Rong; Wang, Jun-Xia; Cui, Cheng-Du; Li, Wen-Xue; Cui, Zheng-Yun; Yin, Xi-Jun; Kang, Jin-Dan

2017-05-01

To investigate the effect of the small molecule, RepSox, on the expression of developmentally important genes and the pre-implantation development of rhesus monkey-pig interspecies somatic cell nuclear transfer (iSCNT) embryos. Rhesus monkey cells expressing the monomeric red fluorescent protein 1 which have a normal (42) chromosome complement, were used as donor cells to generate iSCNT embryos. RepSox increased the expression levels of the pluripotency-related genes, Oct4 and Nanog (p  0.05), this was not significant. RepSox can improve the developmental potential of rhesus monkey-pig iSCNT embryos by regulating the expression of pluripotency-related genes.

Core-Shell-Corona Micelles with a Responsive Shell.

Science.gov (United States)

Gohy, Jean-François; Willet, Nicolas; Varshney, Sunil; Zhang, Jian-Xin; Jérôme, Robert

2001-09-03

A reactor for the synthesis of gold nanoparticles is one of the uses of a poly(styrene)-block-poly(2-vinylpyridine)-block-poly(ethylene oxide) triblock copolymer (PS-b-P2VP-b-PEO) which forms core-shell-corona micelles in water. Very low polydispersity spherical micelles are observed that consist of a PS core surrounded by a pH-sensitive P2VP shell and a corona of PEO chains end-capped by a hydroxyl group. The corona can act as a site for attaching responsive or sensing molecules. © 2001 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins.

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Louise Madsen

Full Text Available The protein known as p97 or VCP in mammals and Cdc48 in yeast is a versatile ATPase complex involved in several biological functions including membrane fusion, protein folding, and activation of membrane-bound transcription factors. In addition, p97 plays a central role in degradation of misfolded secretory proteins via the ER-associated degradation pathway. This functional diversity of p97 depends on its association with various cofactors, and to further our understanding of p97 function it is important that these cofactors are identified and analyzed. Here, we isolate and characterize the human protein named Rep8 or Ubxd6 as a new cofactor of p97. Mouse Rep8 is highly tissue-specific and abundant in gonads. In testes, Rep8 is expressed in post-meiotic round spermatids, whereas in ovaries Rep8 is expressed in granulosa cells. Rep8 associates directly with p97 via its UBX domain. We show that Rep8 is a transmembrane protein that localizes to the ER membrane with its UBX domain facing the cytoplasm. Knock-down of Rep8 expression in human cells leads to a decreased association of p97 with the ER membrane and concomitantly a retarded degradation of misfolded ER-derived proteasome substrates. Thus, Rep8 tethers p97 to the ER membrane for efficient ER-associated degradation.

Interlaboratory reproducibility of DiversiLab rep-PCR typing and clustering of Acinetobacter baumannii isolates.

Science.gov (United States)

Higgins, Paul G; Hujer, Andrea M; Hujer, Kristine M; Bonomo, Robert A; Seifert, Harald

2012-01-01

We have investigated the reproducibility of DiversiLab rep-PCR fingerprints between two laboratories with the aim of determining if the fingerprints and clustering are laboratory-specific or portable. One-hundred non-duplicate Acinetobacter baumannii isolates were used in this study. DNA isolation and rep-PCR were each performed separately in two laboratories and rep-PCR patterns generated in laboratory A were compared with those from laboratory B. Twelve A. baumannii isolates processed in laboratory A showed ≥98 % pattern similarity with the corresponding 12 isolates tested in laboratory B and were considered identical. Sixty-four isolates showed 95-97.9 % similarity with their corresponding isolates. Twenty-three isolates showed 90-94 % similarity with the corresponding isolates, while one isolate showed only 87.4 % similarity. However, intra-laboratory clustering was conserved: isolates that clustered in laboratory A also clustered in laboratory B. While clustering was conserved and reproducible at two different laboratories, demonstrating the robustness of rep-PCR, interlaboratory comparison of individual isolate fingerprints showed more variability. This comparison allows conclusions regarding clonality to be reached independent of the laboratory where the analysis is performed.

El concepto de República en José Martí

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Dr. Ibrahim Hidalgo

2015-10-01

Full Text Available El acercamiento a una visión martiana sobre el concepto de la república es la esencia del artículo, donde se parte del análisis de sus textos, situando el concepto de república en el centro de su pensamiento y su actuar políticos e ideológicos, que han devenido objeto de análisis y valoraciones desde diversos ángulos, perspectivas y proyecciones por autores que a lo largo del siglo XX, y en la actualidad. El elemento esencial de la concepción es el ser individualmente considerado, cuya unión constituye el pueblo, que deviene así no un ente abstracto y amorfo, sino un conglomerado de personas

Applications of the rep-PCR DNA fingerprinting technique to study microbial diversity, ecology and evolution.

Science.gov (United States)

Ishii, Satoshi; Sadowsky, Michael J

2009-04-01

A large number of repetitive DNA sequences are found in multiple sites in the genomes of numerous bacteria, archaea and eukarya. While the functions of many of these repetitive sequence elements are unknown, they have proven to be useful as the basis of several powerful tools for use in molecular diagnostics, medical microbiology, epidemiological analyses and environmental microbiology. The repetitive sequence-based PCR or rep-PCR DNA fingerprint technique uses primers targeting several of these repetitive elements and PCR to generate unique DNA profiles or 'fingerprints' of individual microbial strains. Although this technique has been extensively used to examine diversity among variety of prokaryotic microorganisms, rep-PCR DNA fingerprinting can also be applied to microbial ecology and microbial evolution studies since it has the power to distinguish microbes at the strain or isolate level. Recent advancement in rep-PCR methodology has resulted in increased accuracy, reproducibility and throughput. In this minireview, we summarize recent improvements in rep-PCR DNA fingerprinting methodology, and discuss its applications to address fundamentally important questions in microbial ecology and evolution.

Safety and efficacy of REP 2139 and pegylated interferon alfa-2a for treatment-naive patients with chronic hepatitis B virus and hepatitis D virus co-infection (REP 301 and REP 301-LTF): a non-randomised, open-label, phase 2 trial.

Science.gov (United States)

Bazinet, Michel; Pântea, Victor; Cebotarescu, Valentin; Cojuhari, Lilia; Jimbei, Pavlina; Albrecht, Jeffrey; Schmid, Peter; Le Gal, Frédéric; Gordien, Emmanuel; Krawczyk, Adalbert; Mijočević, Hrvoje; Karimzadeh, Hadi; Roggendorf, Michael; Vaillant, Andrew

2017-12-01

REP 2139 clears circulating hepatitis B virus (HBV) surface antigen (HBsAg), enhancing the restoration of functional control of HBV infection by immunotherapy. We assessed the safety and efficacy of REP 2139 and pegylated interferon alfa-2a in patients with chronic HBV and hepatitis D virus (HDV) co-infection. In this open-label, non-randomised, phase 2 trial, patients aged 18-55 years, who were treatment naive, hepatitis B e antigen [HBeAg] negative, anti-hepatitis D antigen [HDAg] positive, and HDV RNA positive, with serum HBsAg concentrations of more than 1000 IU/mL, and a history of HDV infection for 6 months or more before treatment, were recruited at Toma Ciorbă Hospital of Infectious Diseases in Chișinău, Moldova. Patients were excluded if they had HDV superinfection, liver infections other than HBV and HDV, or liver cirrhosis. Patients received 500 mg intravenous REP 2139 once per week for 15 weeks, followed by combined therapy with 250 mg intravenous REP 2139 and 180 μg subcutaneous pegylated interferon alfa-2a once per week for 15 weeks, then monotherapy with 180 μg pegylated interferon alfa-2a once per week for 33 weeks. The primary endpoints assessed at the end of treatment were the safety and tolerability of the treatment regimen, analysed in the intention-to-treat population. Secondary outcomes included the proportion of patients with serum HBsAg less than 50 IU/mL, the proportion of patients with suppressed HBV DNA, and the proportion of patients who maintained these responses through follow-up. The REP 301 trial is registered with ClinicalTrials.gov, number NCT02233075. We also did an additional follow-up at 1 year after the end of treatment, as an interim analysis of the REP 301-LTF trial (planned duration 3 years), registered with ClinicalTrials.gov, number NCT02876419, which is ongoing but not recruiting patients. Between Sept 8, 2014, and Jan 27, 2015, we enrolled 12 patients into the REP 301 study. All 12 patients experienced at least one

A Comparison of Molecular Typing Methods Applied to Enterobacter cloacae complex: hsp60 Sequencing, Rep-PCR, and MLST

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Roberto Viau

2017-02-01

Full Text Available Molecular typing using repetitive sequenced-based PCR (rep-PCR and hsp60 sequencing were applied to a collection of diverse Enterobacter cloacae complex isolates. To determine the most practical method for reference laboratories, we analyzed 71 E. cloacae complex isolates from sporadic and outbreak occurrences originating from 4 geographic areas. While rep-PCR was more discriminating, hsp60 sequencing provided a broader and a more objective geographical tracking method similar to multilocus sequence typing (MLST. In addition, we suggest that MLST may have higher discriminative power compared to hsp60 sequencing, although rep-PCR remains the most discriminative method for local outbreak investigations. In addition, rep-PCR can be an effective and inexpensive method for local outbreak investigation.

Identification of Tilletia species using rep-PCR fingerprinting technique

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Župunski Vesna

2011-01-01

Full Text Available Analyzing 167 non-processed seed samples of wheat, it was found that 145 samples (86.8 % were contaminated with Tilletia species, while 22 (13.2 % samples were not contaminated. By using rep-PCR fingerprinting technique, it was found that DNA isolates of T. tritici originated from Serbian wheat samples had 80 % similarity with positive control for T. tritici. One isolate shared similarity of 60% with T. tritici, T. controversa and T. laevis. It was supposed that this isolate belongs to T. bromi. Isolate of T. laevis shared a similarity of 70 % with isolates of T. tritici and T. controversa, while T. walkeri was more than 10 % similar with T. tritici, T. controversa and T. laevis. Although T. controversa and T. tritici had high percent of genetic similarity, they were clustered separately. Our results suggest that rep-PCR fingerprinting could be a useful tool for monitoring presence of morphologically similar Tilletia species in wheat production areas.

Genetic Diversity and Evidence for Transmission of Streptococcus mutans by DiversiLab rep-PCR.

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Momeni, Stephanie S; Whiddon, Jennifer; Cheon, Kyounga; Ghazal, Tariq; Moser, Stephen A; Childers, Noel K

2016-09-01

This two-part study investigated the genetic diversity and transmission of Streptococcus mutans using the DiversiLab repetitive extragenic palindromic PCR (rep-PCR) approach. For children with S. mutans and participating household members, analysis for evidence of unrelated child-to-child as well as intra-familial transmission was evaluated based on commonality of genotypes. A total of 169 index children and 425 household family members from Uniontown, Alabama were evaluated for genetic diversity using rep-PCR. Thirty-four unique rep-PCR genotypes were observed for 13,906 S. mutans isolates. For transmission, 117 child and household isolates were evaluated for shared genotype (by child and by genotype cases, multiple matches possible for each child). Overall, children had 1-9 genotypes and those with multiple genotypes were 2.3 times more likely to have caries experience (decayed, missing and filled teeth/surfaces>0). Only 28% of children shared all genotypes within the household, while 72% had at least 1 genotype not shared with anyone in the household. Children had genotype(s) not shared with any household members in 157 cases. In 158 cases children and household members shared a genotype in which 55% (87/158 cases) were shared with more than one family member. Children most frequently shared genotypes with their mothers (54%; 85/158), siblings (46%; 72/158) and cousins (23%; 37/158). A reference library for S. mutans for epidemiological surveillance using the DiversiLab rep-PCR approach is detailed. The genetic diversity of S. mutans in this population demonstrated frequent commonality of genotypes. Evidence for both child-to-child and intra-familial transmission of S. mutans was observed by rep-PCR. Copyright © 2016 Elsevier B.V. All rights reserved.

Yeast identification by sequencing, biochemical kits, MALDI-TOF MS and rep-PCR DNA fingerprinting.

Science.gov (United States)

Zhao, Ying; Tsang, Chi-Ching; Xiao, Meng; Chan, Jasper F W; Lau, Susanna K P; Kong, Fanrong; Xu, Yingchun; Woo, Patrick C Y

2017-12-08

No study has comprehensively evaluated the performance of 28S nrDNA and ITS sequencing, commercial biochemical test kits, MALDI-TOF MS platforms, and the emerging rep-PCR DNA fingerprinting technology using a cohort of yeast strains collected from a clinical microbiology laboratory. In this study, using 71 clinically important yeast isolates (excluding Candida albicans) collected from a single centre, we determined the concordance of 28S nrDNA and ITS sequencing and evaluated the performance of two commercial test kits, two MALDI-TOF MS platforms, and rep-PCR DNA fingerprinting. 28S nrDNA and ITS sequencing showed complete agreement on the identities of the 71 isolates. Using sequencing results as the standard, 78.9% and 71.8% isolates were correctly identified using the API 20C AUX and Vitek 2 YST ID Card systems, respectively; and 90.1% and 80.3% isolates were correctly identified using the Bruker and Vitek MALDI-TOF MS platforms, respectively. Of the 18 strains belonging to the Candida parapsilosis species complex tested by DiversiLab automated rep-PCR DNA fingerprinting, all were identified only as Candida parapsilosis with similarities ≥93.2%, indicating the misidentification of Candida metapsilosis and Candida orthopsilosis. However, hierarchical cluster analysis of the rep-PCR DNA fingerprints of these three species within this species complex formed three different discrete clusters, indicating that this technology can potentially differentiate the three species. To achieve higher accuracies of identification, the databases of commercial biochemical test kits, MALDI-TOF MS platforms, and DiversiLab automated rep-PCR DNA fingerprinting needs further enrichment, particularly for uncommonly encountered yeast species. © The Author 2017. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Open-Source Wax RepRap 3-D Printer for Rapid Prototyping Paper-Based Microfluidics.

Science.gov (United States)

Pearce, J M; Anzalone, N C; Heldt, C L

2016-08-01

The open-source release of self-replicating rapid prototypers (RepRaps) has created a rich opportunity for low-cost distributed digital fabrication of complex 3-D objects such as scientific equipment. For example, 3-D printable reactionware devices offer the opportunity to combine open hardware microfluidic handling with lab-on-a-chip reactionware to radically reduce costs and increase the number and complexity of microfluidic applications. To further drive down the cost while improving the performance of lab-on-a-chip paper-based microfluidic prototyping, this study reports on the development of a RepRap upgrade capable of converting a Prusa Mendel RepRap into a wax 3-D printer for paper-based microfluidic applications. An open-source hardware approach is used to demonstrate a 3-D printable upgrade for the 3-D printer, which combines a heated syringe pump with the RepRap/Arduino 3-D control. The bill of materials, designs, basic assembly, and use instructions are provided, along with a completely free and open-source software tool chain. The open-source hardware device described here accelerates the potential of the nascent field of electrochemical detection combined with paper-based microfluidics by dropping the marginal cost of prototyping to nearly zero while accelerating the turnover between paper-based microfluidic designs. © 2016 Society for Laboratory Automation and Screening.

Reasonable potential for GHG savings by anaerobic biomethane in Germany and UK derived from economic and ecological analyses

International Nuclear Information System (INIS)

Horschig, Thomas; Adams, Paul W.R.; Röder, Mirjam; Thornley, Patricia; Thrän, Daniela

2016-01-01

Highlights: • Biomethane market potential estimation through biogas market analyses. • Country comparison of Germany and the UK in terms of bioenergy. • Assessment of possible greenhouse gas emission savings by biomethane. • Role of biomethane to achieve greenhouse gas reduction goals in Germany and the UK was investigated. - Abstract: This study introduces a new approach to estimate biomethane market potential by analysing biogas markets and their relative environmental and economic advantages. This potential is then combined with greenhouse gas emission values for different feedstock shares (farm-fed and waste-fed systems) and different application share to determine the possible contribution of biomethane to national greenhouse gas emission saving goals. Markets that are considered are Germany and the UK being the biggest emitters of CO_2_e_q in the European Union. The current use was compared with the scenarios (i) market projection, derived from literature study and (ii) reasonable potential, derived from environmental and economic calculations. The current market status is presented to show the past market development until the present date and associated greenhouse gas savings. Additionally the potential of biomethane to contribute to greenhouse gas emission savings is extensively described. Results indicate that the share of application in Germany is more environmental beneficial than the one in the UK achieving higher greenhouse gas savings at comparable feed-in level. In contrast, the UK has a higher share of waste-fed systems to produce biomethane. The use of biomethane in CHP plants achieves the highest GHG emission savings and if organic waste is used as feedstock the possible savings are even higher. With an increase of biomethane used in CHP plants and a decrease of biomethane used for direct heating the savings in the UK could increase up to 52%. Current savings of 2446 kt CO_2_e_q (Germany) and 606 kt CO_2_e_q (UK) can be extended to 4483

La república conservadora

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Matías Muraca

2011-12-01

Full Text Available Este artigo tem como objetivo revisar e analisar como aparece a discussão sobre República ao longo dos anos de redemocratização na Argentina, articulando com outra categoria da teoria política: o populismo. Os conteúdos e sentidos da demanda republicana que se conjuga com populismo são analisados nas edições de um dos mais importantes jornais argentinos durante o segundo governo de Carlos Saúl Menem (1995-1999 e o governo de Aliança (1999-2001. Especificamente, é revisado nas Colunas de Opinião do Diário “La Nación” a primeira etapa das críticas republicanas centradas em um dos seus componentes principais: a questão da corrupção associada a problemática da moral.

A república e o sonho The republic and its dream

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Maria Tereza Chaves de Mello

2011-06-01

Full Text Available O desencanto com a República brasileira tem sido tema de reflexões desde os seus momentos iniciais. Buscando os conteúdos concretos dos sonhos republicanos na década de 1880 e na Primeira República vamos achar uma importante defasagem entre eles não exatamente em função do marco cronológico, mas do grupo social que, respectivamente, os acalentou.The disillusion with the Brazilian Republic since its first days has been a topic of academician reflexions. Examinating the concrete contents of the 1880`s and the First Republic republican dreams we will find a substantive difference between them. To be exact, this difference must not be related to the chronological demarcation but to the social group that embraced each of them.

Molecular epidemiology of Acinetobacter baumannii and Acinetobacter nosocomialis in Germany over a 5-year period (2005-2009).

Science.gov (United States)

Schleicher, X; Higgins, P G; Wisplinghoff, H; Körber-Irrgang, B; Kresken, M; Seifert, H

2013-08-01

To investigate the species distribution within the Acinetobacter calcoaceticus-Acinetobacter baumannii complex and the molecular epidemiology of A. baumannii and Acinetobacter nosocomialis, 376 Acinetobacter isolates were collected prospectively from hospitalized patients at 15 medical centres in Germany during three surveillance studies conducted over a 5-year period. Species identification was performed by molecular methods. Imipenem minimum inhibitory concentrations (MIC) were determined by broth microdilution. The prevalence of the most common carbapenemase-encoding genes was investigated by oxacillinase (OXA) -multiplex polymerase chain reaction (PCR). The molecular epidemiology was investigated by repetitive sequence-based PCR (rep-PCR; DiversiLab™). Acinetobacter pittii was the most prevalent Acinetobacter species (n = 193), followed by A. baumannii (n = 140), A. calcoaceticus (n = 10) and A. nosocomialis (n = 8). The majority of A. baumannii was represented by sporadic isolates (n = 70, 50%) that showed unique rep-PCR patterns, 25 isolates (18%) clustered with one or two other isolates, and only 45 isolates (32%) belonged to one of the previously described international clonal lineages. The most prevalent clonal lineage was international clone (IC) 2 (n = 34) and IC 1 (n = 6). According to CLSI, 25 A. baumannii isolates were non-susceptible to imipenem (MIC ≥ 8 mg/L), all of which produced an OXA-58-like or OXA-23-like carbapenemase. The rate of imipenem susceptibility among A. baumannii isolates decreased from 96% in 2005 to 76% in 2009. All other Acinetobacter isolates were susceptible to imipenem. The population structure of carbapenem-susceptible A. baumannii in Germany is highly diverse. Imipenem non-susceptibility was strongly associated with the clonal lineages IC 2 and IC 1. These data underscore the high clonality of carbapenem-resistant A. baumannii isolates. © 2012 The Authors. Clinical Microbiology and Infection © 2012 European Society of

Production of recombinant AAV vectors encoding insulin-like growth factor I is enhanced by interaction among AAV rep regulatory sequences

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Dilley Robert

2009-01-01

Full Text Available Abstract Background Adeno-associated virus (AAV vectors are promising tools for gene therapy. Currently, their potential is limited by difficulties in producing high vector yields with which to generate transgene protein product. AAV vector production depends in part upon the replication (Rep proteins required for viral replication. We tested the hypothesis that mutations in the start codon and upstream regulatory elements of Rep78/68 in AAV helper plasmids can regulate recombinant AAV (rAAV vector production. We further tested whether the resulting rAAV vector preparation augments the production of the potentially therapeutic transgene, insulin-like growth factor I (IGF-I. Results We constructed a series of AAV helper plasmids containing different Rep78/68 start codon in combination with different gene regulatory sequences. rAAV vectors carrying the human IGF-I gene were prepared with these vectors and the vector preparations used to transduce HT1080 target cells. We found that the substitution of ATG by ACG in the Rep78/68 start codon in an AAV helper plasmid (pAAV-RC eliminated Rep78/68 translation, rAAV and IGF-I production. Replacement of the heterologous sequence upstream of Rep78/68 in pAAV-RC with the AAV2 endogenous p5 promoter restored translational activity to the ACG mutant, and restored rAAV and IGF-I production. Insertion of the AAV2 p19 promoter sequence into pAAV-RC in front of the heterologous sequence also enabled ACG to function as a start codon for Rep78/68 translation. The data further indicate that the function of the AAV helper construct (pAAV-RC, that is in current widespread use for rAAV production, may be improved by replacement of its AAV2 unrelated heterologous sequence with the native AAV2 p5 promoter. Conclusion Taken together, the data demonstrate an interplay between the start codon and upstream regulatory sequences in the regulation of Rep78/68 and indicate that selective mutations in Rep78/68 regulatory elements

High-rep-rate Thomson scattering for LHD

Science.gov (United States)

den Hartog, D. J.; Borchardt, M. T.; Holly, D. J.; Schmitz, O.; Yasuhara, R.; Yamada, I.; Funaba, H.; Osakabe, M.; Morisaki, T.

2017-10-01

A high-rep-rate pulse-burst laser system is being built for the LHD Thomson scattering (TS) diagnostic. This laser will have two operating scenarios, a fast-burst sequence of 15 kHz rep rate for at least 15 ms, and a slow-burst sequence of 1 kHz for at least 50 ms. There will be substantial flexibility in burst sequences for tailoring to experimental requirements. This new laser system will operate alongside the existing lasers in the LHD TS diagnostic, and will use the same beamline. This increase in temporal resolution capability complements the high spatial resolution (144 points) of the LHD TS diagnostic, providing unique measurement capability unmatched on any other fusion experiment. The new pulse-burst laser is a straightforward application of technology developed at UW-Madison, consisting of a Nd:YAG laser head with modular flashlamp drive units and a customized control system. Variable pulse-width drive of the flashlamps is accomplished by IGBT (insulated gate bipolar transistor) switching of electrolytic capacitor banks. Direct control of the laser Pockels cell drive enables optimal pulse energy extraction, producing >1.5 J q-switched pulses with 20 ns FWHM. Burst operation of this laser system will be used to capture fast time evolution of the electron temperature and density profiles during events such as ELMs, RMP perturbations, and various MHD modes. This work is supported by the U. S. Department of Energy and the National Institute for Fusion Science (Japan).

El Ecoturismo en los Humedales: Análisis de las Potencialidades de República Dominicana

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Francisco Orgaz Agüera

2014-04-01

Full Text Available El turismo se configura como uno de los principales motores económicos de República Dominicana. En este sentido, el turismo de sol y playa es la principal tipología turística en el país. Aunque, República Dominicana cuenta con numerosas potencialidades turísticas para poner en marchas nuevas formas de turismo: Turismo gastronómico, turismo ornitológico, turismo cultural, ecoturismo, etc. El principal objetivo de esta investigación es analizar las potencialidades existentes en República Dominicana para desarrollar el ecoturismo en las zonas de humedales. La metodología ha consistido en un trabajo de campo, a través de las entrevistas, los grupos de discusión y la observación participante. Los resultados muestran las grandes potencialidades que tiene el país para desarrollar el ecoturismo en los humedales, y contribuir así, al desarrollo socioeconómico de las comunidades locales. 

Identification of new isolates of Bacillus thuringiensis using rep-PCR products and delta-endotoxin electron microscopy

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A.S.G. Lima

2002-01-01

Full Text Available PCR has been used to analyze the distribution of REP (Repetitive Extragenic Palindromic and ERIC (Enterobacterial Repetitive Intergenic Consensus sequences (rep-PCR found within the genome of the bacterium Bacillus thuringiensis, with the purpose to analyze the genetic similarities among 56 subspecies samples and 95 field isolates. The PCR products were analyzed by EB-AGE (ethidium bromide-agarose electrophoresis and then submitted to banding comparisons, based on the Phyllip software algorithm. When the banding similarities were considered for comparison purposes among all the strains, the phylogenic tree patterns varied according to the rep-PCR primers considered, but, from a broader point of view, the ERIC sequences produced better results, which, together with electron microscopy analysis of the released parasporal bodies and colony morphology characteristics, allowed to detect two possible new subspecies of B. thuringiensis.

REP Executive Education focuses on Midwest plant off-site emergency preparedness

OpenAIRE

Center for Homeland Defense and Security

2015-01-01

Center for Homeland Defense and Security News and Stories, PRESS RELEASES The Center for Homeland Defense and Security burgeoning Radiological Emergency Preparedness (REP) Executive Education Program convened June 8-12 with a special focus on emergency preparedness policy and strategic issues for...

Therapeutic Antiviral Effect of the Nucleic Acid Polymer REP 2055 against Persistent Duck Hepatitis B Virus Infection

Science.gov (United States)

Noordeen, Faseeha; Scougall, Catherine A.; Grosse, Arend; Qiao, Qiao; Ajilian, Behzad B.; Reaiche-Miller, Georget; Finnie, John; Werner, Melanie; Broering, Ruth; Schlaak, Joerg F.; Vaillant, Andrew; Jilbert, Allison R.

2015-01-01

Previous studies have demonstrated that nucleic acid polymers (NAPs) have both entry and post-entry inhibitory activity against duck hepatitis B virus (DHBV) infection. The inhibitory activity exhibited by NAPs prevented DHBV infection of primary duck hepatocytes in vitro and protected ducks from DHBV infection in vivo and did not result from direct activation of the immune response. In the current study treatment of primary human hepatocytes with NAP REP 2055 did not induce expression of the TNF, IL6, IL10, IFNA4 or IFNB1 genes, confirming the lack of direct immunostimulation by REP 2055. Ducks with persistent DHBV infection were treated with NAP 2055 to determine if the post-entry inhibitory activity exhibited by NAPs could provide a therapeutic effect against established DHBV infection in vivo. In all REP 2055-treated ducks, 28 days of treatment lead to initial rapid reductions in serum DHBsAg and DHBV DNA and increases in anti-DHBs antibodies. After treatment, 6/11 ducks experienced a sustained virologic response: DHBsAg and DHBV DNA remained at low or undetectable levels in the serum and no DHBsAg or DHBV core antigen positive hepatocytes and only trace amounts of DHBV total and covalently closed circular DNA (cccDNA) were detected in the liver at 9 or 16 weeks of follow-up. In the remaining 5/11 REP 2055-treated ducks, all markers of DHBV infection rapidly rebounded after treatment withdrawal: At 9 and 16 weeks of follow-up, levels of DHBsAg and DHBcAg and DHBV total and cccDNA in the liver had rebounded and matched levels observed in the control ducks treated with normal saline which remained persistently infected with DHBV. These data demonstrate that treatment with the NAP REP 2055 can lead to sustained control of persistent DHBV infection. These effects may be related to the unique ability of REP 2055 to block release of DHBsAg from infected hepatocytes. PMID:26560490

RiskREP: Risk-Based Security Requirements Elicitation and Prioritization (extended version)

NARCIS (Netherlands)

Herrmann, Andrea; Morali, A.

2010-01-01

Today, companies are required to be in control of the security of their IT assets. This is especially challenging in the presence of limited budgets and conflicting requirements. Here, we present Risk-Based Requirements Elicitation and Prioritization (RiskREP), a method for managing IT security

Averróis e a República de Platão

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Pereira, Rosalie Helena de Souza

2007-01-01

Full Text Available Sobre República é o único comentário de uma obra de Platão deixado por Averróis, o comentador por antonomásia, diga-se de Aristóteles. Embora se tenha perdido o original árabe, a teles. Embora se tenha perdido o original árabe, a posteridade recebeu uma versão hebraíca e duas latinas. O comentário (ou paráfrase a República de Platão pode ser considerado uma obra original - divida em três livros - já que apenas um terço dela corresponde ao texto platônico. Além de apresentar conceitos aristotélicos retirados da Ética Nicomaquéia e de obras políticas de Al-Farabi, Averróis apresenta reflexões próprias e faz críticas à sociedade em que vive

El montaje de la transición argentina. Un análisis de los films La República perdida, La República perdida II y Evita, quien quiera oír que oiga

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Paola Judith Margulis

2012-01-01

Full Text Available El presente artículo se propone reconstruir una zona de la historia del documental argentino a partir del abordaje de tres films que tuvieron un alto impacto en Argentina hacia la transición democrática: La República perdida (Miguel Pérez, 1983, su secuela La República perdida II (Miguel Pérez, 1986 y Evita, quien quiera oír que oiga (Eduardo Mignogna, 1984. Dada la importancia de estos films -tanto en términos políticos como de impacto en el público-, intentaremos situarlos en contexto y analizar algunos aspectos inherentes a su lógica fílmica.

CoolRep H22: Synthesis report on R and D results on geological disposal up to 2009

International Nuclear Information System (INIS)

Umeki, Hiroyuki; Hioki, Kazumasa; Osawa, Hideaki; Fujita, Tomoo; Shibata, Masahiro; Makino, Hitoshi; Takeuchi, Shinji; Ishimaru, Tsuneari

2011-02-01

The Japan Atomic Energy Agency (JAEA) has been performing research and development on geological disposal technology of high level radioactive waste. At the end of fiscal year 2009, the Geological Isolation Research and Development Directorate of JAEA made publicly available the 'CoolRep H22', which is a web-based report that summarizes the R and D results, on its website. This document reports the contents of CoolRep H22. (author)

Iberia : capital federal de la IIª República Española (Un proyecto de Rubio i Tuduri

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Carlos Sambricio

1996-01-01

Full Text Available A los pocos meses de proclamarse, en 1931, la II República Española, Nicolás Rubio i Tuduri presentaba —en el marco de la Exposición organizada por la Asociación de Arquitectos de Cataluña, celebrada en la barcelonesa Galería Maragall— una propuesta un tanto sorprendente: el proyecto de una nueva Capital Federal de la República Española que él denominaba Iberia.

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The RXL motif of the African cassava mosaic virus Rep protein is necessary for rereplication of yeast DNA and viral infection in plants

Energy Technology Data Exchange (ETDEWEB)

Hipp, Katharina; Rau, Peter; Schäfer, Benjamin [Institut für Biomaterialien und biomolekulare Systeme, Abteilung für Molekularbiologie und Virologie der Pflanzen, Universität Stuttgart, Pfaffenwaldring 57, D-70550 Stuttgart (Germany); Gronenborn, Bruno [Institut des Sciences du Végétal, CNRS, 91198 Gif-sur-Yvette (France); Jeske, Holger, E-mail: holger.jeske@bio.uni-stuttgart.de [Institut für Biomaterialien und biomolekulare Systeme, Abteilung für Molekularbiologie und Virologie der Pflanzen, Universität Stuttgart, Pfaffenwaldring 57, D-70550 Stuttgart (Germany)

2014-08-15

Geminiviruses, single-stranded DNA plant viruses, encode a replication-initiator protein (Rep) that is indispensable for virus replication. A potential cyclin interaction motif (RXL) in the sequence of African cassava mosaic virus Rep may be an alternative link to cell cycle controls to the known interaction with plant homologs of retinoblastoma protein (pRBR). Mutation of this motif abrogated rereplication in fission yeast induced by expression of wildtype Rep suggesting that Rep interacts via its RXL motif with one or several yeast proteins. The RXL motif is essential for viral infection of Nicotiana benthamiana plants, since mutation of this motif in infectious clones prevented any symptomatic infection. The cell-cycle link (Clink) protein of a nanovirus (faba bean necrotic yellows virus) was investigated that activates the cell cycle by binding via its LXCXE motif to pRBR. Expression of wildtype Clink and a Clink mutant deficient in pRBR-binding did not trigger rereplication in fission yeast. - Highlights: • A potential cyclin interaction motif is conserved in geminivirus Rep proteins. • In ACMV Rep, this motif (RXL) is essential for rereplication of fission yeast DNA. • Mutating RXL abrogated viral infection completely in Nicotiana benthamiana. • Expression of a nanovirus Clink protein in yeast did not induce rereplication. • Plant viruses may have evolved multiple routes to exploit host DNA synthesis.

The RXL motif of the African cassava mosaic virus Rep protein is necessary for rereplication of yeast DNA and viral infection in plants

International Nuclear Information System (INIS)

Hipp, Katharina; Rau, Peter; Schäfer, Benjamin; Gronenborn, Bruno; Jeske, Holger

2014-01-01

Geminiviruses, single-stranded DNA plant viruses, encode a replication-initiator protein (Rep) that is indispensable for virus replication. A potential cyclin interaction motif (RXL) in the sequence of African cassava mosaic virus Rep may be an alternative link to cell cycle controls to the known interaction with plant homologs of retinoblastoma protein (pRBR). Mutation of this motif abrogated rereplication in fission yeast induced by expression of wildtype Rep suggesting that Rep interacts via its RXL motif with one or several yeast proteins. The RXL motif is essential for viral infection of Nicotiana benthamiana plants, since mutation of this motif in infectious clones prevented any symptomatic infection. The cell-cycle link (Clink) protein of a nanovirus (faba bean necrotic yellows virus) was investigated that activates the cell cycle by binding via its LXCXE motif to pRBR. Expression of wildtype Clink and a Clink mutant deficient in pRBR-binding did not trigger rereplication in fission yeast. - Highlights: • A potential cyclin interaction motif is conserved in geminivirus Rep proteins. • In ACMV Rep, this motif (RXL) is essential for rereplication of fission yeast DNA. • Mutating RXL abrogated viral infection completely in Nicotiana benthamiana. • Expression of a nanovirus Clink protein in yeast did not induce rereplication. • Plant viruses may have evolved multiple routes to exploit host DNA synthesis

RiskREP: Risk-Based Security Requirements Elicitation and Prioritization

OpenAIRE

Herrmann, Andrea; Morali, A.; Etalle, Sandro; Wieringa, Roelf J.; Niedrite, Laila; Strazdina, Renate; Wangler, Benkt

2011-01-01

Companies are under pressure to be in control of their assets but at the same time they must operate as efficiently as possible. This means that they aim to implement “good-enough security‿ but need to be able to justify their security investment plans. In this paper, we present a Risk-Based Requirements Prioritization method (RiskREP) that extends misuse case-based methods with IT architecture based risk assessment and countermeasure definition and prioritization. Countermeasure prioritizati...

Revolución versus reforma educativa en la segunda república española. Elementos de ruptura

Directory of Open Access Journals (Sweden)

Juan Manuel FERNÁNDEZ SORIA

2010-03-01

Full Text Available RESUMEN: Están fuera de toda duda las conexiones existentes entre la República de 1931-35 y la de 1936-39. En este sentido estamos de acuerdo con quienes afirman que el estallido de la guerra del 36 es el resultado de un proceso que arranca del mismo año en que se proclama la II República, iniciándose ya entonces —como sostiene Andrés M. Kramer— la «mecánica de guerra civil». La educación republicana en tiempo de guerra no puede quedar fuera de esta consideración, porque aquélla sumerge sus cimientos más profundos en la política educativa de 1931-35. Efectivamente, muchas de las acciones educativas y culturales llevadas a cabo durante la guerra no tendrían fácil explicación si no se examina previamente la tarea de la República del 31 en estos mismos aspectos.

Discriminação de sorovares de Salmonella spp. isolados de carcaças de frango por REP e ERIC-PCR e fagotipagem do sorovar Enteriditis Discrimination of Salmonella serovars isolated from chicken meat by REP and ERIC-PCR and phagotyping of Enteriditis sorovar

Directory of Open Access Journals (Sweden)

Iliana Alcocer

2006-06-01

Full Text Available Salmonelose é a infecção bacteriana de origem alimentar mais freqüente no Paraná, Brasil, e os surtos estão associados, principalmente, ao consumo de ovos, carne de aves e derivados. Os objetivos deste trabalho foram identificar os sorovares de Salmonella isolados de carcaças de frango e caracterizá-los molecularmente por REP e ERIC-PCR, assim como identificar os fagotipos de Salmonella Enteriditis. Dos 25 isolados de Salmonella spp. analisados, 18 foram identificados como Enteriditis, 4 como Braenderup, 2 como Worthington e 1 como infantis. Dos 18 isolados de Enteriditis, 14 foram PT4, 2 PT4a, 1 PT7 e 1 RDNC, por se tratar de colônia rugosa. REP-PCR forneceu padrão eletroforético distinto de 10 a 13 bandas distribuídas entre 120 e 2072 pb para cada sorovar diferente testado. A ERIC-PCR mostrou um padrão de 4 a 5 bandas entre 180 e 1000 pb e foi menos discriminativa quando comparada à REP-PCR. Os resultados encontrados confirmaram que a fagotipagem é uma ferramenta útil e discriminativa para o sorovar Enteriditis. Apesar do pequeno número de sorovares testados, os resultados sugerem que a REP-PCR parece ser um método atrativo a ser utilizado no futuro para a discriminação preliminar de sorovares de Salmonella.Salmonellosis is the most prevalent bacterial food-borne disease in the State of Paraná, Brazil, and the outbreaks are often associated with consumption of poultry products. The aim of this study was to serotype Salmonella strains isolated from chicken carcasses and characterize them molecularly using REP and ERIC-PCR. The phage types of Salmonella Enteriditis were also identified. Of the 25 Salmonella strains analysed, 18 were identified as Enteriditis, 4 as Braenderup, 2 as Worthington and 1 as infantis. Of the 18 Enteriditis isolates, 14 were PT4, 2 PT4a, 1 PT7 and 1 "reacted, but did not conform" - RDNC. Distinct REP-PCR profiles with 10 to 13 fragments distributed between 120 and 2072 pb were easily obtained for

A repA-based ELISA for discriminating cattle vaccinated with Brucella suis 2 from those naturally infected with Brucella abortus and Brucella melitensis.

Science.gov (United States)

Wang, Jing-Yu; Wu, Ning; Liu, Wan-Hua; Ren, Juan-Juan; Tang, Pan; Qiu, Yuan-Hao; Wang, Chi-Young; Chang, Ching-Dong; Liu, Hung-Jen

2014-01-01

The commonest ways of diagnosing brucellosis in animals include the Rose-Bengal plate agglutination test, the buffered plate agglutination test (BPA), the slide agglutination test, the complement fixation test, and the indirect enzyme linked immunosorbent assay (I-ELISA). However, these methods cannot discriminate the Brucella vaccine strain (Brucella suis strain 2; B. suis S2) from naturally acquired virulent strains. Of the six common Brucella species, Brucella melitensis, Brucella abortus, and B. suis are the commonest species occurring in China. To develop an ELISA assay that can differentiate between cows inoculated with B. suis S2 and naturally infected with B. abortus and B. melitensis, genomic sequences from six Brucella spp. (B. melitensis, B. abortus, B. suis, Brucella canis, Brucella neotomae and Brucella ovis) were compared using Basic Local Alignment Search Tool software. One particular gene, the repA-related gene, was found to be a marker that can differentiate B. suis from B. abortus and B. melitensis. The repA-related gene of B. suis was PCR amplified and subcloned into the pET-32a vector. Expressed repA-related protein was purified and used as an antigen. The repA-based ELISA was optimized and used as specific tests. In the present study, serum from animals inoculated with the B. suis S2 vaccine strain had positive repA-based ELISA results. In contrast, the test-positive reference sera against B. abortus and B. melitensis had negative repA-based ELISA results. The concordance rate between B. abortus antibody-negative (based on the repA-based ELISA) and the Brucella gene-positive (based on the 'Bruce ladder' multiplex PCR) was 100%. Therefore, the findings suggest that the repA-based ELISA is a useful tool for differentiating cows vaccinated with the B. suis S2 and naturally infected with B. abortus and B. melitensis. Copyright © 2014 Elsevier Ltd. All rights reserved.

Progressive Conversion from B-rep to BSP for Streaming Geometric Modeling.

Science.gov (United States)

Bajaj, Chandrajit; Paoluzzi, Alberto; Scorzelli, Giorgio

2006-01-01

We introduce a novel progressive approach to generate a Binary Space Partition (BSP) tree and a convex cell decomposition for any input triangles boundary representation (B-rep), by utilizing a fast calculation of the surface inertia. We also generate a solid model at progressive levels of detail. This approach relies on a variation of standard BSP tree generation, allowing for labeling cells as in, out and fuzzy, and which permits a comprehensive representation of a solid as the Hasse diagram of a cell complex. Our new algorithm is embedded in a streaming computational framework, using four types of dataflow processes that continuously produce, transform, combine or consume subsets of cells depending on their number or input/output stream. A varied collection of geometric modeling techniques are integrated in this streaming framework, including polygonal, spline, solid and heterogeneous modeling with boundary and decompositive representations, Boolean set operations, Cartesian products and adaptive refinement. The real-time B-rep to BSP streaming results we report in this paper are a large step forward in the ultimate unification of rapid conceptual and detailed shape design methodologies.

Análisis de la relación comercial entre la República de Colombia y la República de Costa Rica

OpenAIRE

Romero Escobar, Juán Sebastián; Bermudez Monroy, María Gabriela

2012-01-01

Dadas las relaciones de cooperación internacional que presentan las Repúblicas de Colombia y Costa Rica, que se evidencia en los fuertes vínculos comerciales existentes entre las dos naciones, Proexport por medio de su oficina comercial en Costa Rica, ha mantenido al tanto la situación en la que se desenvuelve la alianza comercial entre Colombia y Costa Rica. Él último de estos informes, demuestra la potencialidad de Costa Rica como un mercado para los bienes colombianos y una posibilidad par...

CARACTERIZACIÓN MOLECULAR MEDIANTE rep-PCR DE AISLADOS NATIVOS DE Bacillus thuringiensis, OBTENIDOS DE MUESTRAS DE SUELO

Directory of Open Access Journals (Sweden)

Fabián Galvis

2014-01-01

Full Text Available Bacillus thuringiensis es una bacteria Gram-positiva formadora de esporas, que produ - ce cristales parasporales de naturaleza proteica, tóxicos contra diferentes órdenes de insectos y biodegradables e inocuos para otras especies. Esta investigación empleó el modelo experimen - tal, que mediante técnicas de observación permi - tió, la identificación microbiológica y bioquímica de B. thuringiensis a partir de muestras de suelo de los municipios de Cúcuta, El Zulia, Los Patios, San Cayetano y Villa del Rosario, Norte de Santander, Colombia, y su posterior caracteri - zación con los marcadores moleculares Bc-Rep y MB1. Se identificaron microbiológica y bioquí - micamente 10 aislados como B. thuringiensis ; los resultados del análisis filogenético mostraron diferencias significativas en los agrupamientos obtenidos con los marcadores Bc-Rep y MB1. Con Bc-Rep se registró un índice de similaridad bajo (18%, mientras que con el marcador MB1 se obtuvo un índice mayor de similitud, 58%. En este trabajo se evidenció una gran variabilidad genética entre los aislados, que mostraron a los marcadores Bc-Rep y MB1 como altamente efectivos para diferenciar cepas estrechamente relacionadas, convirtiéndose en una herramienta genética de gran valor para estudios de identifi-cación y diversidad en B. thuringiensis.

Ultra Fast, High Rep Rate, High Voltage Spark Gap Pulser

Science.gov (United States)

1995-07-01

current rise time. The spark gap was designed to have a coaxial geometry reducing its inductance. Provisions were made to pass flowing gas between the...ULTRA FAST, HIGH REP RATE, HIGH VOLTAGE SPARK GAP PULSER Robert A. Pastore Jr., Lawrence E. Kingsley, Kevin Fonda, Erik Lenzing Electrophysics and...Modeling Branch AMSRL-PS-EA Tel.: (908)-532-0271 FAX: (908)-542-3348 U.S. Army Research Laboratory Physical Sciences Directorate Ft. Monmouth

Variation in a surface-exposed region of the Mycoplasma pneumoniae P40 protein as a consequence of homologous DNA recombination between RepMP5 elements.

Science.gov (United States)

Spuesens, Emiel B M; van de Kreeke, Nick; Estevão, Silvia; Hoogenboezem, Theo; Sluijter, Marcel; Hartwig, Nico G; van Rossum, Annemarie M C; Vink, Cornelis

2011-02-01

Mycoplasma pneumoniae is a human pathogen that causes a range of respiratory tract infections. The first step in infection is adherence of the bacteria to the respiratory epithelium. This step is mediated by a specialized organelle, which contains several proteins (cytadhesins) that have an important function in adherence. Two of these cytadhesins, P40 and P90, represent the proteolytic products from a single 130 kDa protein precursor, which is encoded by the MPN142 gene. Interestingly, MPN142 contains a repetitive DNA element, termed RepMP5, of which homologues are found at seven other loci within the M. pneumoniae genome. It has been hypothesized that these RepMP5 elements, which are similar but not identical in sequence, recombine with their counterpart within MPN142 and thereby provide a source of sequence variation for this gene. As this variation may give rise to amino acid changes within P40 and P90, the recombination between RepMP5 elements may constitute the basis of antigenic variation and, possibly, immune evasion by M. pneumoniae. To investigate the sequence variation of MPN142 in relation to inter-RepMP5 recombination, we determined the sequences of all RepMP5 elements in a collection of 25 strains. The results indicate that: (i) inter-RepMP5 recombination events have occurred in seven of the strains, and (ii) putative RepMP5 recombination events involving MPN142 have induced amino acid changes in a surface-exposed part of the P40 protein in two of the strains. We conclude that recombination between RepMP5 elements is a common phenomenon that may lead to sequence variation of MPN142-encoded proteins.

How Often Is p[subscript rep] Close to the True Replication Probability?

Science.gov (United States)

Trafimow, David; MacDonald, Justin A.; Rice, Stephen; Clason, Dennis L.

2010-01-01

Largely due to dissatisfaction with the standard null hypothesis significance testing procedure, researchers have begun to consider alternatives. For example, Killeen (2005a) has argued that researchers should calculate p[subscript rep] that is purported to indicate the probability that, if the experiment in question were replicated, the obtained…

Birmingham Rep, Youth and Community, and the Products and Possibilities of Precarity

Science.gov (United States)

Cochrane, Claire

2017-01-01

Birmingham Rep, a leading producing theatre based in the UK's "second city", has historically had a complex relationship with the cultural priorities of its home city. In recent years, Birmingham City Council has faced multiple challenges represented by debt burden, government-imposed cuts in public funding, scandals linked to failing…

Oral microbial profile discriminates breast-fed from formula-fed infants.

Science.gov (United States)

Holgerson, Pernilla L; Vestman, Nelly R; Claesson, Rolf; Ohman, Carina; Domellöf, Magnus; Tanner, Anne C R; Hernell, Olle; Johansson, Ingegerd

2013-02-01

Little is known about the effect of diet on the oral microbiota of infants, although diet is known to affect the gut microbiota. The aims of the present study were to compare the oral microbiota in breast-fed and formula-fed infants, and investigate growth inhibition of streptococci by infant-isolated lactobacilli. A total of 207 mothers consented to participation of their 3-month-old infants. A total of 146 (70.5%) infants were exclusively and 38 (18.4%) partially breast-fed, and 23 (11.1%) were exclusively formula-fed. Saliva from all of their infants was cultured for Lactobacillus species, with isolate identifications from 21 infants. Lactobacillus isolates were tested for their ability to suppress Streptococcus mutans and S sanguinis. Oral swabs from 73 infants were analysed by the Human Oral Microbe Identification Microarray (HOMIM) and by quantitative polymerase chain reaction for Lactobacillus gasseri. Lactobacilli were cultured from 27.8% of exclusively and partially breast-fed infants, but not from formula-fed infants. The prevalence of 14 HOMIM-detected taxa, and total salivary lactobacilli counts differed by feeding method. Multivariate modelling of HOMIM-detected bacteria and possible confounders clustered samples from breast-fed infants separately from formula-fed infants. The microbiota of breast-fed infants differed based on vaginal or C-section delivery. Isolates of L plantarum, L gasseri, and L vaginalis inhibited growth of the cariogenic S mutans and the commensal S sanguinis: L plantarum >L gasseri >L vaginalis. The microbiota of the mouth differs between 3-month-old breast-fed and formula-fed infants. Possible mechanisms for microbial differences observed include species suppression by lactobacilli indigenous to breast milk.

Control conception for REP 1300 MW units of the Electricite de France

International Nuclear Information System (INIS)

Blanc, P.; Guesnier, G.

1986-01-01

The paper describes the control equipment for the REP 1300 MW units including the reactor protection system, the control rods drive system and nuclear instrumentation, the control of the auxiliaries in the systems important for the reactor safety and the safety survey computer. Finally, the digital connections between different control systems are presented

SEATURTLE: Sustained Engagement Autonomous Tracking of Underwater RepTiLEs

OpenAIRE

Budd, Johnathan

2015-01-01

While oceans cover the majority of our planet, these vast expanses remain relatively unexplored. Among the most interesting parts of the ocean are the shallow reef systems, which contain a huge amount of the planet’s biodiversity. The Sustained Engagement Autonomous Tracking of Underwater RepTiLEs or SEATURTLE is a low cost Autonomous Underwater Vehicle designed to carry out missions in these shallow environments. Its small displacement and precise movement make it ideal for navigating tight ...

Overview of RepLab 2014: Author Profiling and Reputation Dimensions for Online Reputation Management

NARCIS (Netherlands)

Amigó, E.; Carrillo-de-Albornoz, J.; Chugur, I.; Corujo, A.; Gonzalo, J.; Meij, E.; de Rijke, M.; Spina, D.; Kanoulas, E.; Lupu, M.; Clough, P.; Sanderson, M.; Hall, M.; Hanbury, A.; Toms, E.

2014-01-01

This paper describes the organisation and results of RepLab 2014, the third competitive evaluation campaign for Online Reputation Management systems. This year the focus lied on two new tasks: reputation dimensions classification and author profiling, which complement the aspects of reputation

Automated Production of High Rep Rate Foam Targets

Science.gov (United States)

Hall, F.; Spindloe, C.; Haddock, D.; Tolley, M.; Nazarov, W.

2016-04-01

Manufacturing low density targets in the numbers needed for high rep rate experiments is highly challenging. This report summarises advances from manual production to semiautomated and the improvements that follow both in terms of production time and target uniformity. The production process is described and shown to be improved by the integration of an xyz robot with dispensing capabilities. Results are obtained from manual and semiautomated production runs and compared. The variance in the foam thickness is reduced significantly which should decrease experimental variation due to target parameters and could allow for whole batches to be characterised by the measurement of a few samples. The work applies to both foil backed and free standing foam targets.

Investigation of Genetic Diversity of Wilsonomyces carpophilus in Khorasan Razavi Using rep-PCR Marker

Directory of Open Access Journals (Sweden)

R. Barazandeh Aq Kariz

2017-08-01

Full Text Available Introduction: Shot hole disease of stone fruit trees resulted from Wilsonomyces carpophilus can weaken the trees and reduce the quantity and quality of the crops worldwide particularly in semi-arid regions. Coryneum blight or shot hole disease infects all the stone fruit trees including peach, nectarine, apricot, sour cherry, plum, cherry, and almond. One of the most important strategies to manage any plant disease is to use resistant cultivars. In this way, it is very important to have knowledge about the status of genetic diversity and to determine the relationship between isolates of the causal agent fungus. The main objective of the present research was to study the genetic diversity of W. carpophilus in Khorasan Razavi province using the rep-PCR molecular fingerprinting method. Materials and Methods: Sampling was performed from peach, nectarine, plum, apricot and cherry orchards of Quchan, Torqabeh, Shandiz, Chenaran, Neishabur, Kalat, Torbat Heidarieh and Mashhad during spring and summer of 2012 and 2013. Mono-conidial isolates were recovered from infected leaves, fruits, and twigs of different parts of orchards. Infected collected leaves, twigs, and fruits were transferred to the laboratory. By using techniques of Klimesova and Prasil (1989 and Mehta (1998 from the cut parts between infected and healthy tissues of each isolate, cuts of 2-3 mm from leaf, fruit and twig were prepared by the scalpel. These pieces were surface sterilized with 1% sodium hypochlorite liquid about 1 to 3 minutes based on the thickness of tissue. Then, the samples were cultured on PDA, MEA, and WA media and incubated at 18, 20, and 25 °C. The isolated fungi were purified and identified. The research was performed on 20 fungal isolates collected from different stone fruit trees. Genomic DNA was amplified using BOX A1R, ERIC2, ERIC1R, REP2-I, and REP1R-I primers. Thirty-eight of 39 fragments amplified were polymorphic for 100 to 5000 base pairs. Similarity matrix

RepExplore: addressing technical replicate variance in proteomics and metabolomics data analysis.

Science.gov (United States)

Glaab, Enrico; Schneider, Reinhard

2015-07-01

High-throughput omics datasets often contain technical replicates included to account for technical sources of noise in the measurement process. Although summarizing these replicate measurements by using robust averages may help to reduce the influence of noise on downstream data analysis, the information on the variance across the replicate measurements is lost in the averaging process and therefore typically disregarded in subsequent statistical analyses.We introduce RepExplore, a web-service dedicated to exploit the information captured in the technical replicate variance to provide more reliable and informative differential expression and abundance statistics for omics datasets. The software builds on previously published statistical methods, which have been applied successfully to biomedical omics data but are difficult to use without prior experience in programming or scripting. RepExplore facilitates the analysis by providing a fully automated data processing and interactive ranking tables, whisker plot, heat map and principal component analysis visualizations to interpret omics data and derived statistics. Freely available at http://www.repexplore.tk enrico.glaab@uni.lu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.

FED-R2: concept and magnet design of a low-cost FED

International Nuclear Information System (INIS)

Williams, J.E.C.; Becker, H.; Blackfield, D.; Bobrov, E.; Bromberg, L.; Cohn, D.R.; Diatchenko, N.; LeClaire, R.

1982-12-01

High performance resistive magnet technology was used to develop a design for a compact, low cost version of the fusion engineering device FED. We refer to this design as FED-R2, for FED-resistive magnet design 2 to distinguish it from the larger resistive magnet design for FED which uses demountable coils (FED-R1). The main objectives of FED-R2 are: (1) to demonstrate reliable, quasi-steady state (long pulse, high duty factor) operation with Q/sub p/ approx. 5; (2) to demonstrate Q/sub p/ > 5 operation for a limited number of pulses; (3) to provide high neutron flux for irradiation of nuclear test modules with a total area greater tha 20m 2 ; (4) to utilize steady-state RF current drive if this option appears promising. Based upon the costing codes at the Fusion Engineering Design Center and upon TFTR costs, the estimated direct costs of FED-R2 would be on the range 380 to 460M, a factor of about 2 below that of the baseline FED design

Repérage d’Images Ordinaires : Analyse des Requêtes des Chercheurs d’Images

Directory of Open Access Journals (Sweden)

Elaine Ménard

2009-06-01

also emphasizes the pressing necessity to optimize the methods used for image processing, in order to facilitate image retrieval and dissemination in multilingual environments. Résumé Depuis quelques années, le web est devenu un média incontournable pour la diffusion de ressources multilingues. Cependant, les différences linguistiques constituent souvent un obstacle majeur aux échanges de documents scientifiques, culturels, pédagogiques et commerciaux. En plus de cette diversité linguistique, on constate le développement croissant de bases de données et de collections composées de différents types de documents textuels ou multimédias, ce qui complexifie également le processus de repérage documentaire. Par exemple, les collections d’images numériques sont aussi nombreuses que diversifiées. Le besoin de repérer une image spécifique dans diverses collections est devenu une préoccupation partagée par plusieurs communautés. La croissance du web a mis en relief le besoin pressant de se doter d’outils propres à la description des images dans le but de faciliter leur repérage, puisque l’on retrouve celles-ci dans la plupart des ressources disponibles. Cette recherche compare le repérage d’images dans deux contextes linguistiques différents : un contexte monolingue, c’est-à-dire que la langue de la requête (français est la même que la langue d’indexation (français; et un contexte multilingue où la langue de la requête (français est différente de la langue d’indexation (anglais. Cet article présente les résultats de l’analyse des requêtes formulées par les participants pour repérer un ensemble d’images ordinaires représentant des objets de la vie quotidienne, en contexte de repérage multilingue. L’examen des termes contenus dans les requêtes des chercheurs d’images révèle les tendances observées sur le plan terminologique, perceptuel et structurel. Les participants emploient généralement des requêtes simples

FEDS

DEFF Research Database (Denmark)

Venable, John; Pries-Heje, Jan; Baskerville, Richard

2016-01-01

Evaluation of design artefacts and design theories is a key activity in Design Science Research (DSR), as it provides feedback for further development and (if done correctly) assures the rigour of the research. However, the extant DSR literature provides insufficient guidance on evaluation...... to enable Design Science Researchers to effectively design and incorporate evaluation activities into a DSR project that can achieve DSR goals and objectives. To address this research gap, this research paper develops, explicates, and provides evidence for the utility of a Framework for Evaluation in Design...... Science (FEDS) together with a process to guide design science researchers in developing a strategy for evaluating the artefacts they develop within a DSR project. A FEDS strategy considers why, when, how, and what to evaluate. FEDS includes a two-dimensional characterisation of DSR evaluation episodes...

Use of a rep-PCR system to predict species in the Aspergillus section Nigri

Science.gov (United States)

The Aspergillus niger aggregate within the A. section Nigri, is a group of black-spored aspergilli which taxonomy has been elusive. REP-PCR has become a rapid and cost-effective method for genotyping fungi and bacteria. In the present study, we evaluated the discriminatory power of a semi-automate...

Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments.

Science.gov (United States)

Nicolas, Armel; Alazard-Dany, Nathalie; Biollay, Coline; Arata, Loredana; Jolinon, Nelly; Kuhn, Lauriane; Ferro, Myriam; Weller, Sandra K; Epstein, Alberto L; Salvetti, Anna; Greco, Anna

2010-09-01

Adeno-associated virus (AAV) is a human parvovirus that replicates only in cells coinfected with a helper virus, such as adenovirus or herpes simplex virus type 1 (HSV-1). We previously showed that nine HSV-1 factors are able to support AAV rep gene expression and genome replication. To elucidate the strategy of AAV replication in the presence of HSV-1, we undertook a proteomic analysis of cellular and HSV-1 factors associated with Rep proteins and thus potentially recruited within AAV replication compartments (AAV RCs). This study resulted in the identification of approximately 60 cellular proteins, among which factors involved in DNA and RNA metabolism represented the largest functional categories. Validation analyses indicated that the cellular DNA replication enzymes RPA, RFC, and PCNA were recruited within HSV-1-induced AAV RCs. Polymerase delta was not identified but subsequently was shown to colocalize with Rep within AAV RCs even in the presence of the HSV-1 polymerase complex. In addition, we found that AAV replication is associated with the recruitment of components of the Mre11/Rad50/Nbs1 complex, Ku70 and -86, and the mismatch repair proteins MSH2, -3, and -6. Finally, several HSV-1 factors were also found to be associated with Rep, including UL12. We demonstrated for the first time that this protein plays a role during AAV replication by enhancing the resolution of AAV replicative forms and AAV particle production. Altogether, these analyses provide the basis to understand how AAV adapts its replication strategy to the nuclear environment induced by the helper virus.

Utilisation of Rep-PCR to track microbes in aerosols collected adjacent to their source, a saline lake in Victoria, Australia.

Science.gov (United States)

Munday, Chris I; O'Loingsigh, Tadhg; Tapper, Nigel J; De Deckker, Patrick; Allison, Gwen E

2013-04-15

Dust storms are a major source of aerosolized bacteria, especially in the drought conditions experienced in Australia in the decade to 2009. The major aims of this project were to identify the culturable bacteria in environmental samples and to genetically fingerprint all isolates using repetitive element PCR (Rep-PCR) to investigate the possibility of tracking isolates from their source into the atmosphere. Four field trips were conducted to a dry lake in western Victoria, Australia to sample aerosols and sediments. Aerosols were collected at heights up to 150 m using vacuum pumps with filters attached to a tethered helium balloon, while corresponding sediments were collected in sterile polypropylene tubes. Isolates were cultivated on Tryptic Soy Agar, R2 Agar and Marine Agar, and grown in dark conditions at ambient temperature. By sequencing the 16S rRNA gene of 270 isolates, fifteen different bacterial families were identified, with both the aerosols and sediments dominated by the Bacillaceae family. Four sets of Rep-PCR primers were tested, with the ERIC and (GTG)5 primers proving to be the most suitable for fingerprinting the cultured taxa. Rep-PCR revealed very high strain diversity in the samples collected, however some strains were still able to be tracked from sediments up to 150 m in height. This shows the potential of Rep-PCR, however very large reference databases would be required for the technique to be more useful. Copyright © 2013 Elsevier B.V. All rights reserved.

Biomass in Germany

International Nuclear Information System (INIS)

Chapron, Thibaut

2014-01-01

This document provides, first, an overview of biomass industry in Germany: energy consumption and renewable energy production, the French and German electricity mix, the 2003-2013 evolution of renewable electricity production and the 2020 forecasts, the biomass power plants, plantations, biofuels production and consumption in Germany. Then, the legal framework of biofuels development in Germany is addressed (financial incentives, tariffs, direct electricity selling). Next, a focus is made on biogas production both in France and in Germany (facilities, resources). Finally, the French-German cooperation in the biomass industry and the research actors are presented

Increased kidney growth in formula-fed versus breast-fed healthy infants

DEFF Research Database (Denmark)

Schmidt, Ida M; Damgaard, Ida N; Boisen, Kirsten A

2004-01-01

versus breast feeding on kidney growth in a cohort of 631 healthy children examined at birth, and at 3 and 18 months of age. Kidney size was determined by ultrasonography and related to gender, age, body size, and feeding category (fully breast fed, partially breast fed, or fully formula fed at 3 months...

Weimar Germany

DEFF Research Database (Denmark)

Reckendrees, Alfred

The Weimar Republic is analysed within the framework of limited and open access orders. Germany had developed into a mature limited access order before World War I, with rule of law and open economic access but only limited access to politics. After the war, Germany developed toward an open access...... order; this process was, however, not sustainable. Two interpretations are discussed, which both pose a challenge to the limited access-open access framework: (1.) Weimar Germany was the first open access order that failed; (2.) sufficiency conditions of the sustainability of open access are not yet...

Rep-PCR typing of Staphylococcus spp. strains in meat paste production line and identification of their origin

Directory of Open Access Journals (Sweden)

Ivan Manga

2015-05-01

Full Text Available A meat paste production line and its microbial parameters have been evaluated in single Czech company. The raw meat paste samples before heat treatment were tested positively for the presence of three staphylococci species: Staphylococcus aureus, Staphylococcus haemolyticus and Staphylococcus epidermidis. Subsequent microbial analysis of meat paste components and ingredients (fresh meat, water, spices, equipment identified only the spices used as positive for S. aureus (coriander, cinnamon, badian, mustard – (10 - 40 cfu/g and S. haemolyticus strains (juniper, ginger. The collection of sixteen collected strains (S. aureus (n = 4, S. haemolyticus (n = 4, S. epidermidis (n = 8 has been typed with the rep-PCR method utilising (GTG5 primer. Analysis of the fingerprints using the unweighted pair-group method using arithmetic averages (UPGMA clustering method revealed presence of eleven strain clusters with similarity lower than 90%: two fingerprint clusters of S. aureus, three individual clusters characteristic for S. haemolyticus and six different S. epidermidis specific clusters. The S. aureus strains from different types of spice were identical, resp. very similar. Molecular tracking composed from the rep-PCR analysis of acquired isolates and comparison among all collected fingerprints confirmed the spices to be the source of both S. aureus and S. haemolyticus strains identified in raw meat paste. The additional rep-PCR analysis of the S. epidermidis collection confirmed usability and performance of this method. The antibiotic susceptibility to fourteen individual antibiotics has been examined among the collected staphylococci strains. The predominant erythromycin resistance (68.8% was followed with the resistance to amoxicillin/clavulanic acid (56.2%. Other resistances observed were less frequent (clindamycin – 12.5%, oxacillin – 6.3%, tetracycline – 6.3%, sulphamethoxazole-trimethoprim – 6.3%, chloramphenicol – 6.3%, novobiocin – 6

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African Journals Online (AJOL)

Algeria, 95. Australia, 5. Bahrain, 2. Belgium, 6. Benin, 1. Brazil, 10. Bulgaria, 2. Canada, 3. Chile, 3. China, 16. Côte d'Ivoire, 1. Croatia, 2. Egypt, Arab Rep. 5. Ethiopia, 2. Finland, 2. France, 7. Germany, 11. Ghana, 5. Hong Kong SAR, China, 3. India, 68. Indonesia, 2. Iran, Islamic Rep. 79. Iraq, 6. Israel, 1. Italy, 8. Jordan, 1.

MetaRep, an extended CMAS 3D program to visualize mafic (CMAS, ACF-S, ACF-N) and pelitic (AFM-K, AFM-S, AKF-S) projections

Science.gov (United States)

France, Lydéric; Nicollet, Christian

2010-06-01

MetaRep is a program based on our earlier program CMAS 3D. It is developed in MATLAB ® script. MetaRep objectives are to visualize and project major element compositions of mafic and pelitic rocks and their minerals in the pseudo-quaternary projections of the ACF-S, ACF-N, CMAS, AFM-K, AFM-S and AKF-S systems. These six systems are commonly used to describe metamorphic mineral assemblages and magmatic evolutions. Each system, made of four apices, can be represented in a tetrahedron that can be visualized in three dimensions with MetaRep; the four tetrahedron apices represent oxides or combination of oxides that define the composition of the projected rock or mineral. The three-dimensional representation allows one to obtain a better understanding of the topology of the relationships between the rocks and minerals and relations. From these systems, MetaRep can also project data in ternary plots (for example, the ACF, AFM and AKF ternary projections can be generated). A functional interface makes it easy to use and does not require any knowledge of MATLAB ® programming. To facilitate the use, MetaRep loads, from the main interface, data compiled in a Microsoft Excel ™ spreadsheet. Although useful for scientific research, the program is also a powerful tool for teaching. We propose an application example that, by using two combined systems (ACF-S and ACF-N), provides strong confirmation in the petrological interpretation.

Impacto de la inmigración haitiana sobre el mercado laboral y las finanzas públicas de la República Dominicana

OpenAIRE

Aristy-Escuder, Jaime

2010-01-01

La pobreza del pueblo haitiano influye de forma determinante sobre los flujos migratorios hacia la República Dominicana. Este artículo se propone estimar el impacto de la inmigración haitiana sobre el mercado laboral dominicano, así como sobre sus finanzas públicas. Luego de un exhaustivo análisis teórico y aplicado, el artículo concluye que la mano de obra haitiana es complementaria al capital y a la mano de obra calificada de la República Dominicana. En cambio, es sustituta d...

La República de los historiadores del Paraguay posbélico

OpenAIRE

Telesca, Ignacio

2015-01-01

En ocasión del bicentenario de la adopción de la República como sistema de gobierno, e independiente tanto de España como de Buenos Aires, este artículo reflexiona sobre como los historiadores paraguayos de fines de siglo XIX reflexionaron sobre el tema, relacionándolo con la adopción de un nuevo sistema de gobierno con la constitución de 1870 (calco de la argentina). Fil: Telesca, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET ...

Protección contra la violencia sexual en la República Democrática del Congo

OpenAIRE

Mosely, Sarah; Cetinoglu, Talita; Glad, Marit

2010-01-01

Si bien la prestación de servicios a los supervivientes de la violencia sexual es la principal prioridad en la República Democrática del Congo, la protección para las mujeres y niñas también puede mejorarse.

75 FR 78694 - Proposed Residential Exchange Program Settlement Agreement Proceeding (REP-12); Public Hearing...

Science.gov (United States)

2010-12-16

..., 2010, on BPA's Web site at http://www.bpa.gov/corporate/ratecase/2012/rep-12.cfm . Hard copies of these.... Bonneville Power Admin., 928 F.2d 905 (9th Cir. 1991). Due to the burdensome, expensive and contentious... Electric v. Bonneville Power Admin., 501 F.3d 1009 (9th Cir. 2007) (PGE), the Court found that BPA had...

El Museo de Arte del Banco de la República

Directory of Open Access Journals (Sweden)

Boletín Cultural y Bibliográfico Banco de la República

2003-05-01

Full Text Available El Banco de la República desde sus comienzos, en los años veinte y treinta del siglo pasado, ha apoyado la cultura. De esas épocas datan los inicios de las colecciones de numismática y orfebrería, creadas con la intención de preservar y defender el patrimonio artístico y cultural colombiano. A ese atesoramiento se une el desarrollo de otras colecciones que son referencia obligada para el conocimiento de la historia de Colombia: la colección documental (bibliográfica, hemerográfica, audiovisual, la de arte, a partir de 1957 y la de filatelia.

Liberalismo, iluminismo y romanticismo: el problema de la libertad en dos novelas de la República Restaurada

Directory of Open Access Journals (Sweden)

Verónica Hernández Landa Valencia

2016-07-01

Full Text Available El artículo propone una reflexión en torno a la forma como influyen tres corrientes de pensamiento, el liberalismo, el iluminismo y el romanticismo, en la representación del problema de la libertad en dos novelas históricas publicadas en la República Restaurada: Monja y casada, virgen y mártir, de Vicente Riva Palacio, y El pecado del siglo, de José Tomás de Cuéllar. Se busca mostrar que dichas corrientes se entrecruzan en un solo texto, que ello contribuye a la conformación de un concepto de libertad restringida y que la forma específica que adquiere ese concepto se explica a partir de la postura ideológica y política de los autores en el contexto de la República Restaurada.

Variation in extragenic repetitive DNA sequences in Pseudomonas syringae and potential use of modified REP primers in the identification of closely related isolates

Directory of Open Access Journals (Sweden)

Elif Çepni

2012-01-01

Full Text Available In this study, Pseudomonas syringe pathovars isolated from olive, tomato and bean were identified by species-specific PCR and their genetic diversity was assessed by repetitive extragenic palindromic (REP-PCR. Reverse universal primers for REP-PCR were designed by using the bases of A, T, G or C at the positions of 1, 4 and 11 to identify additional polymorphism in the banding patterns. Binding of the primers to different annealing sites in the genome revealed additional fingerprint patterns in eight isolates of P. savastanoi pv. savastanoi and two isolates of P. syringae pv. tomato. The use of four different bases in the primer sequences did not affect the PCR reproducibility and was very efficient in revealing intra-pathovar diversity, particularly in P. savastanoi pv. savastanoi. At the pathovar level, the primer BOX1AR yielded shared fragments, in addition to five bands that discriminated among the pathovars P. syringae pv. phaseolicola, P. savastanoi pv. savastanoi and P. syringae pv. tomato. REP-PCR with a modified primer containing C produced identical bands among the isolates in a pathovar but separated three pathovars more distinctly than four other primers. Although REP-and BOX-PCRs have been successfully used in the molecular identification of Pseudomonas isolates from Turkish flora, a PCR based on inter-enterobacterial repetitive intergenic concensus (ERIC sequences failed to produce clear banding patterns in this study.

Comparison of semi-automated commercial rep-PCR fingerprinting, spoligotyping, 12-locus MIRU-VNTR typing and single nucleotide polymorphism analysis of the embB gene as molecular typing tools for Mycobacterium bovis.

Science.gov (United States)

Armas, Federica; Camperio, Cristina; Coltella, Luana; Selvaggini, Serena; Boniotti, Maria Beatrice; Pacciarini, Maria Lodovica; Di Marco Lo Presti, Vincenzo; Marianelli, Cinzia

2017-08-04

Highly discriminatory genotyping strategies are essential in molecular epidemiological studies of tuberculosis. In this study we evaluated, for the first time, the efficacy of the repetitive sequence-based PCR (rep-PCR) DiversiLab Mycobacterium typing kit over spoligotyping, 12-locus mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing and embB single nucleotide polymorphism (SNP) analysis for Mycobacterium bovis typing. A total of 49 M. bovis animal isolates were used. DNA was extracted and genomic DNA was amplified using the DiversiLab Mycobacterium typing kit. The amplified fragments were separated and detected using a microfluidics chip with Agilent 2100. The resulting rep-PCR-based DNA fingerprints were uploaded to and analysed using web-based DiversiLab software through Pearson's correlation coefficient. Rep-PCR DiversiLab grouped M. bovis isolates into ten different clusters. Most isolates sharing identical spoligotype, MIRU-VNTR profile or embB gene polymorphism were grouped into different rep-PCR clusters. Rep-PCR DiversiLab displayed greater discriminatory power than spoligotyping and embB SNP analysis but a lower resolution power than the 12-locus MIRU-VNTR analysis. MIRU-VNTR confirmed that it is superior to the other PCR-based methods tested here. In combination with spoligotyping and 12-locus MIRU-VNTR analysis, rep-PCR improved the discriminatory power for M. bovis typing.

Topology reconstruction for B-Rep modeling from 3D mesh in reverse engineering applications

Science.gov (United States)

Bénière, Roseline; Subsol, Gérard; Gesquière, Gilles; Le Breton, François; Puech, William

2012-03-01

Nowadays, most of the manufactured objects are designed using CAD (Computer-Aided Design) software. Nevertheless, for visualization, data exchange or manufacturing applications, the geometric model has to be discretized into a 3D mesh composed of a finite number of vertices and edges. But, in some cases, the initial model may be lost or unavailable. In other cases, the 3D discrete representation may be modified, for example after a numerical simulation, and does not correspond anymore to the initial model. A reverse engineering method is then required to reconstruct a 3D continuous representation from the discrete one. In previous work, we have presented a new approach for 3D geometric primitive extraction. In this paper, to complete our automatic and comprehensive reverse engineering process, we propose a method to construct the topology of the retrieved object. To reconstruct a B-Rep model, a new formalism is now introduced to define the adjacency relations. Then a new process is used to construct the boundaries of the object. The whole process is tested on 3D industrial meshes and bring a solution to recover B-Rep models.

Multiculturalism in Germany

Directory of Open Access Journals (Sweden)

Milan Mesić

2010-12-01

Full Text Available The paper starts out from the recent statement by the German Chancellor Angela Merkel that multiculturalism in Germany is dead. The author draws attention to the unfavourable conditions for the development of multiculturalism in Germany. The reasons are historical, especially the experience of Nazism as well as the German social state. Namely, foreign workers in Germany, although without political rights and socially non-integrated, enjoyed a high degree of working and social rights, including high employment security. In this respect their position significantly differed from that of American workers (immigrants, which is why the struggle for civil rights was not in the foreground for German immigrants. Therefore, “the crisis of multiculturalism” appeared with the immigrants’ “second generation” (children, who have been first hit in the current times of crisis and the increasing deregulation of the labour market. They have remained socially non-integrated and without civil and political rights. It is interesting that the churches, particularly the Protestant one, lead in Germany in the efforts to begin to look at immigrants in a cultural (human sense as well, and have thus been the first to acknowledge that Germany has become a multicultural society. But this term and concept in Germany have remained sketchy, both in the theoretical and political sense. However, they have gained certain sympathy, mainly in parts of liberal-democratic circles – the Green Party leading the way – but more in a symbolic sense in countering xenophobia and cultural exclusion in German society. When multiculturalism was accused of developing “parallel society”, both the right and the left renounced it in favour of the (seemingly neutral concept of integration. The author proves that Germany has become and has remained multicultural, although not a multiculturalist country.

Repérer des sites similaires à une recherche par Google

OpenAIRE

Ginouvès, Véronique

2006-01-01

Repérer des sites similaires à une recherche par Google Afficher graphiquement les liens d’un site avec d’autres sites similaires TouchGraph GoogleBrowser crée des agrégations de sites à partir de l’interrogation de Google. Vous visualisez ainsi des nébuleuses de sites à l’intérieur desquelles vous pouvez naviguer facilement, en sautant d'un groupe à l'autre afin de voir les nuages autour de sujets ou de communautés de sujets. Cet outil a été développé par Alex Shapiro, à partir de la version...

Repše: välislaenuabi katkedes on aasta lõpuks raha läbi / Mikk Salu

Index Scriptorium Estoniae

Salu, Mikk, 1975-

2009-01-01

Läti rahandusminister Einars Repše hoiatas, et kui Lätil ei õnnestu täita oma kohustusi rahvusvaheliste kreeditoride ees ja vähendada 2010. a. eelarvedefitsiiti poole miljardi lati võrra, võib riigikassa rahast tühjaks joosta juba enne aasta lõppu

Announcement of the new version of guidelines for supporting the accelerated market introduction of energy-saving technologies and products. May 22, 1979

Energy Technology Data Exchange (ETDEWEB)

1979-05-01

For an accelerated market introduction of newly- or further-developed products and methods for rational energy application (projects), companies located in the Fed. Rep. of Germany can be granted funds from the Federal Government according to these guidelines and the household means available; introduction into the market without public help is not possible at all, or only with considerable delay, because of high financial risks. The financial support can be granted to those only who undertake the accelerated introduction of products and methods for rational energy application. Projects started before application cannot be promoted. As far as in a project the pre-conditions set by these guidelines and the guidelines for the Federal Programme for 'Promotion of technological innovations and the development necessary for this' are fulfilled, support takes precedence over other points due to these guidelines, if the project is planned for energy saving only.

Hacia una república conservadora : el programa político del Partido Agrario Español

Directory of Open Access Journals (Sweden)

Luis Teófilo Gil Cuadrado

2005-01-01

Full Text Available El Partido Agrario Español (PAE, fundado en enero de 1934 y presidido por José Martínez de Velasco, representó, dentro de la II República española, una alternativa conservadora y, al tiempo, leal al régimen. El programa político del PAE aceptaba la República —a diferencia de otros partidos derechistas del momento, como la CEDA y los monárquicos— y defendía la unidad nacional, el establecimiento de una segunda Cámara legislativa, la protección de la agricultura y la industria mediante aranceles, el libre comercio dentro de las fronteras nacionales y la revisión de algunas leyes del primer bienio como la Reforma Agraria de 1932. El objetivo era la configuración de una República conservadora distinta, en aspectos fundamentales, a la diseñada por la Constitución de 1931 y la legislación del bienio social-republicano.The Spanish Agrarian Party (Partido Agrario Español, PAE, founded in january of 1934 and presided by José Martínez de Velasco, was, in the political life of the Spanish Second Republic, a conservative and republican option. The agrarian program accepted the republican regime —in opposition to other conservative parties, like the CEDA or the monarchists— and defended the national union, the establishment of a Senate, the protection of the national agriculture and industry trough tariffs, the free trade in the Spanish market and the revision of some laws voted in the first biennium like the Agrarian Reform, promulgated in 1932. The idea was to establish a conservative Republic, different, in some fundamental aspects, of the regime designed by the Constitution of 1931 and the legislation approved during the socialist-republican biennium.

Study on Serum Lipoprotein Profile of Exclusive Breast Fed, Mixed Fed and Formula Fed Preterm Infants

Directory of Open Access Journals (Sweden)

Vineet Jaiswal

2017-10-01

Full Text Available Introduction: Breast feeding is protective for atherosclerotic cardiovascular disease, obesity, Diabetes Mellitus (DM and hypertension. Serum lipoprotein is principal risk factor for atherosclerosis. There is growing evidence that risk of Coronary Heart Disease (CHD begins to emerge from infancy. Lipoprotein level is affected by different feeding pattern during infancy. Aim: To compare serum lipoprotein profile of exclusively breast fed, mixed fed and formula fed preterm infant. Materials and Methods: A total of two fifty preterm newborn were recruited at birth and divided into three groups. Group A were Exclusively Breast Fed (EBF, Group B were Mixed Fed (MF and Group C were Formula/bovine milk Fed (FF infants. Preterm newborns with severe sepsis, hypoglycemia, Hypoxic Ischemic Encephalopathy (HIE stage II and III, meconium stained amniotic fluid, pathological jaundice, Hyaline Membrane Disease (HMD, less than 28 weeks gestation, with major congenital anomaly and infants born to mothers with DM, gestational diabetes, hypertension, pre-eclampsia, eclampsia or on long term medications were excluded from the study. Lipoprotein profile estimation was done at four weeks and again at 16 weeks of age. Results: At four weeks of age, Total Cholesterol (TC, Triglyceride (TG, Low Density Lipoprotein (LDL and Very Low Density Lipoprotein (VLDL were higher in EBF infants as compared to MF and FF infants. For TC, difference was significant between EBF vs. MF (p<0.001, EBF vs. FF (p<0.001 and MF vs. FF (p=0.005 infants. At 16 weeks also, TC and HDL were higher in EBF infants as compared to MF and FF infants. For TC, this difference was significant between EBF vs. MF (p<0.001 and EBF vs. FF (p<0.001 infants. When infants were followed up to 16 weeks of age, TC and LDL level fell significantly (p<0.001 in EBF and MF group, a significant (p<0.05 rise for TC was seen in FF group. At 16 weeks of age, there was no significant rise in HDL in EBF infants, but

Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap.

Science.gov (United States)

Conway, J E; Zolotukhin, S; Muzyczka, N; Hayward, G S; Byrne, B J

1997-11-01

Recombinant adeno-associated virus (AAV) type 2 (rAAV) vectors have recently been shown to have great utility as gene transfer agents both in vitro and in vivo. One of the problems associated with the use of rAAV vectors has been the difficulty of large-scale vector production. Low-efficiency plasmid transfection of the rAAV vector and complementing AAV type 2 (AAV-2) functions (rep and cap) followed by superinfection with adenovirus has been the standard approach to rAAV production. The objectives of this study were to demonstrate the ability of a recombinant herpes simplex virus type 1 (HSV-1) amplicon expressing AAV-2 Rep and Cap to support replication and packaging of rAAV vectors. HSV-1 amplicon vectors were constructed which contain the AAV-2 rep and cap genes under control of their native promoters (p5, p19, and p40). An HSV-1 amplicon vector, HSV-RC/KOS or HSV-RC/d27, was generated by supplying helper functions with either wild-type HSV-1 (KOS strain) or the ICP27-deleted mutant of HSV-1, d27-1, respectively. Replication of the amplicon stocks is not inhibited by the presence of AAV-2 Rep proteins, which highlights important differences between HSV-1 and adenovirus replication and the mechanism of providing helper function for productive AAV infection. Coinfection of rAAV and HSV-RC/KOS resulted in the replication and amplification of rAAV genomes. Similarly, rescue and replication of rAAV genomes occurred when rAAV vector plasmids were transfected into cells followed by HSV-RC/KOS infection and when two rAAV proviral cell lines were infected with HSV-RC/KOS or HSV-RC/d27. Production of infectious rAAV by rescue from two rAAV proviral cell lines has also been achieved with HSV-RC/KOS and HSV-RC/d27. The particle titer of rAAV produced with HSV-RC/d27 is equal to that achieved by supplying rep and cap by transfection followed by adenovirus superinfection. Importantly, no detectable wild-type AAV-2 is generated with this approach. These results demonstrate

Country report for Germany [Fast reactors in Germany

International Nuclear Information System (INIS)

Knebel, J.

2007-01-01

Full text: The primary energy consumption in Germany in 2005 was about 492.6 MtSKE in total. The distribution on the main energy sources is: mineral oil: 36.4%, natural gas 22.4%, black coal 13.5%, brown coal 11.4%, nuclear energy 12.6%, water and wind 1.2%, others 2.5%. The net electricity production in Germany in 2005 was about 495.9 billion kWh. The distribution is: nuclear energy 32%, lignite coal 28.9%, black coal 23.1%, oil 0.2%, natural gas 9.1%, water 4.7%, others (being biomass, photovoltaics, wind) 2.0%. In 2005, 18 nuclear power plants were in operation in Germany. In May 2005 the KWO Obrigheim was closed due to the new Atomic law which fixes the phase out of nuclear power production. The net installed nuclear power was 20.7GWel, the net nuclear electricity production was 163TWh, the time availability was 88%. Nuclear makes up for about 50% of the base-load electricity production in Germany. In absolute numbers, Germany is number 5 in nuclear electricity production. Among the top ten nuclear power plants world-wide, in 2005 there were 7 German plants including the plant with the highest amount of electricity produced, being NPP Brokdorf with 1440MWel and 11.98TWhel. The net electricity output of the nuclear power plants is constantly increasing due to power upgrading and higher time availabilities. As for the renewable energies, there is no significant absolute increase except for wind. About 50% of the government support for renewable energies from the Environmental Ministry goes to photovoltaics. The Helmholtz-Gemeinschaft (HGF), summarising 15 national research centres, 24.000 employees and a yearly budget of about 2,1 billion Euro is the largest research organisation in Germany. The HGF identifies and works on complex and urgent questions of society, science and economy, especially concentrating on systems of high complexity. There are six research areas, being energy, earth and environment, health, key technologies, structure of matter, traffic and

Direct Application of Rep-PCR on Type I Sourdough Matrix to Monitor the Dominance and Persistence of a Lactobacillus plantarum Starter Throughout Back-Slopping.

Science.gov (United States)

Dolci, Paola; Cocolin, Luca

2017-08-01

This study describes the optimization and application of repetitive element-PCR (rep-PCR) technique directly on microbial DNA extracted from type I sourdoughs for fast monitoring of a Lb. plantarum starter strain (P1FMC) throughout daily back-slopping. The challenge was to follow and study the performance of a starter culture directly in sourdoughs without cultivation on selective media. The extraction of good quality microbial DNA suitable for amplification from a complex matrix such as dough was the first target. In addition, the objective to obtain a clear rep-PCR profile referable to a specific starter strain among a microbial community was pursued. Co-inoculum trials, in flour matrix, with Lb. plantarum P1FMC and L. lactis LC71 strains and, subsequently, type I sourdough back-slopping trials were performed. The rep-PCR amplification profiles obtained were clearly referable to that of Lb. plantarum P1FMC starter in both co-inoculum trials (also when it was present with one order of magnitude less with respect to L. lactis LC71) and back-slopping trials where it dominated the fermentation process with loads of 10 8 cfu g -1 and prevailed on the autochthonous microbiota. Thus, the approach proposed in this paper could be considered a methodological advancement, based on a culture-independent one-step rep-PCR, suitable for fast monitoring of starter performance. © 2017 Institute of Food Technologists®.

Measurements to know and understand our world

CSIR Research Space (South Africa)

Ostensen, O

2008-02-01

Full Text Available data. ISO/TC 211 Who are we ? ...member list Active members (P-members), 31 countries Australia Austria Belgium Canada China Czech Rep. Denmark Ecuador Finland Germany Hungary Italy Japan Rep. of Korea Malaysia Morocco Netherlands... Group of Experts on Geographical Names • UNGIWG, United Nations Geographic Information Working Group • UN FAO, Food & Agriculture Organization of the United Nations • WMO, World Meteorological Organization • CEN/TC 287, Geographic information...

¿Por qué no la Segunda República Argentina?

Directory of Open Access Journals (Sweden)

Manuel ALCÁNTARA SÁEZ

2009-11-01

Full Text Available RESUMEN: El autor analiza en este artículo el proceso de Reforma Constitucional que se está desarrollando en Argentina. Teniendo en cuenta la coyuntura actual del régimen político, el desarollo de este proceso de reforma y los cambios previstos que van a resultar de esta «Refundación de la República» el autor apunta las posibilidades y problemas que estos datos permiten vislumbrar.ABSTRACT: In this article, the author analyzes the present process of Constitutional Reform in Argentina. Studying the current moment of argentinian political regime, the development of this reform process and possible changes of this «Republic Refoundation» the author points out the possibilities and problems that this information indicates.

La Segunda República, una coyuntura para las mujeres españolas: Cambios y permanencias en las relaciones de género.

OpenAIRE

Merino Hernández, Rosa María

2016-01-01

[ES] En España, no será hasta el período de la Segunda República (1931-1939), cuando las mujeres conseguirán el reconocimiento de ciudadanas de pleno derecho en igualdad con los hombres, respaldadas por la Constitución de 1931. La Segunda República española da voz y derechos a más de la otra mitad de la población del país, por lo que la convierte en una época única, en una etapa nueva donde convivirán el cambio y la permanencia, el avance hacia una nueva sociedad y, dentro de ésta, la emer...

Evolución y relevancia del turismo en la República Dominicana

OpenAIRE

Real Aquino, Héctor Julio

2014-01-01

República Dominicana es un país que durante las últimas décadas ha sufrido grandes transformaciones socioeconómicas, anteriormente su economía dependía casi exclusivamente de la elaboración y exportación de productos agrícolas como: la caña de azúcar, cacao, tabaco, y en menor medida, la industria textil. Ese panorama se ha modificado, debido en gran parte al turismo, dado que este subsector de la economía se ha convertido en la principal actividad económica del país. La evolución y relevanci...

A method and software for segmentation of anatomic object ensembles by deformable m-reps

International Nuclear Information System (INIS)

Pizer, Stephen M.; Fletcher, P. Thomas; Joshi, Sarang; Gash, A. Graham; Stough, Joshua; Thall, Andrew; Tracton, Gregg; Chaney, Edward L.

2005-01-01

Deformable shape models (DSMs) comprise a general approach that shows great promise for automatic image segmentation. Published studies by others and our own research results strongly suggest that segmentation of a normal or near-normal object from 3D medical images will be most successful when the DSM approach uses (1) knowledge of the geometry of not only the target anatomic object but also the ensemble of objects providing context for the target object and (2) knowledge of the image intensities to be expected relative to the geometry of the target and contextual objects. The segmentation will be most efficient when the deformation operates at multiple object-related scales and uses deformations that include not just local translations but the biologically important transformations of bending and twisting, i.e., local rotation, and local magnification. In computer vision an important class of DSM methods uses explicit geometric models in a Bayesian statistical framework to provide a priori information used in posterior optimization to match the DSM against a target image. In this approach a DSM of the object to be segmented is placed in the target image data and undergoes a series of rigid and nonrigid transformations that deform the model to closely match the target object. The deformation process is driven by optimizing an objective function that has terms for the geometric typicality and model-to-image match for each instance of the deformed model. The success of this approach depends strongly on the object representation, i.e., the structural details and parameter set for the DSM, which in turn determines the analytic form of the objective function. This paper describes a form of DSM called m-reps that has or allows these properties, and a method of segmentation consisting of large to small scale posterior optimization of m-reps. Segmentation by deformable m-reps, together with the appropriate data representations, visualizations, and user interface, has been

Euclides da Cunha e a República

Directory of Open Access Journals (Sweden)

Roberto Ventura

1996-04-01

Full Text Available A revisão da República é central na obra de Euclides da Cunha, presente em seus artigos de jornal e na maior parte de seus livros. Analisou o regime republicano não só em Os sertões (1902, em que tratou da guerra de Canudos, como em Contrastes e confrontos (1907 e em Á margem da história (1909. Foi testemunha e intérprete dos rumos do novo regime, que ajudara a fundar com artigos de propaganda política no jornal A Província de S. Paulo.The revision of the Republic is a central concern in the works of Euclides da Cunha. It appears in his newspaper articles and in most of his books. He analysed the republican regime not only in Os sertões (Rebellion in the backlands, 1902, in which he deals with the Canudos War, but also in Contrastes e confrontos (1907 and in À margem da história (1909. He both witnessed and interpreted the trends of the new regime which he had helped to set up with his political articles in the newspaper A Província de S. Paulo.

Realidades de la independencia del Banco de la República Realities of the independence of the Banco de la República

Directory of Open Access Journals (Sweden)

Kalmanovitz Salomón

1997-12-01

Full Text Available La autonomía del banco central Colombiano es parte del proceso político que buscaba reducir el exagerado centralismo colombiano. Sin embargo el poder central no fue limitado en grado suficiente por la Constitución del 1991, como muestra el hecho de que el Ministro de Hacienda es el Presidente de la Junta Directiva del Banco de la República. Esto no sucede en ningun banco independiente del mundo por que los objetivos del gobierno son distintos a los del Banco Central y el Ministerio de Finanzas podría desviar al Banco de sus objetivos antiinflacionarios fundamentales. En Colombia, el gobierno no sólo participa en la Junta para acomodar sus múltiples objetivos sino también hace opocisión pública a la política monetaria y así la desacredita. El articulo plantea que el principio de no reelección hace que el horizonte de tiempo sea muy corto para que el gobierno coseche los frutos de una política de estabilización. El gobierno tiende a gastar en exceso para mejorar su imagen pública y el desajuste lo tiene que enfrentar el gobierno siguiente. De modo que la coordinación entre el Banco Central y el gobierno se torna muy conflictiva.The autonomy of the Central Bank of Colombia is part of a political process which seeks to reduce Colombia' s exaggerated centralismo However, central power was not limited to a sufficient degree by the Constitution of 1991, as demonstrated by the fact that the Minister of Finance is the President of the Board of Directors of the Banco de la República. This does not happen in any independent bank in the world, because the objectives of the government are different from those of the central bank, and the Minister of Finance could divert the Bank away from its fundamental anti-inflationary objectives. This article proposes that the principle of no reelection makes the time horizon very short for the government to reap the fruits of a stabilization policy. The government tends to spend in excess in order to

Analysis of a new strain of Euphorbia mosaic virus with distinct replication specificity unveils a lineage of begomoviruses with short Rep sequences in the DNA-B intergenic region

Directory of Open Access Journals (Sweden)

Argüello-Astorga Gerardo R

2010-10-01

Full Text Available Abstract Background Euphorbia mosaic virus (EuMV is a member of the SLCV clade, a lineage of New World begomoviruses that display distinctive features in their replication-associated protein (Rep and virion-strand replication origin. The first entirely characterized EuMV isolate is native from Yucatan Peninsula, Mexico; subsequently, EuMV was detected in weeds and pepper plants from another region of Mexico, and partial DNA-A sequences revealed significant differences in their putative replication specificity determinants with respect to EuMV-YP. This study was aimed to investigate the replication compatibility between two EuMV isolates from the same country. Results A new isolate of EuMV was obtained from pepper plants collected at Jalisco, Mexico. Full-length clones of both genomic components of EuMV-Jal were biolistically inoculated into plants of three different species, which developed symptoms indistinguishable from those induced by EuMV-YP. Pseudorecombination experiments with EuMV-Jal and EuMV-YP genomic components demonstrated that these viruses do not form infectious reassortants in Nicotiana benthamiana, presumably because of Rep-iteron incompatibility. Sequence analysis of the EuMV-Jal DNA-B intergenic region (IR led to the unexpected discovery of a 35-nt-long sequence that is identical to a segment of the rep gene in the cognate viral DNA-A. Similar short rep sequences ranging from 35- to 51-nt in length were identified in all EuMV isolates and in three distinct viruses from South America related to EuMV. These short rep sequences in the DNA-B IR are positioned downstream to a ~160-nt non-coding domain highly similar to the CP promoter of begomoviruses belonging to the SLCV clade. Conclusions EuMV strains are not compatible in replication, indicating that this begomovirus species probably is not a replicating lineage in nature. The genomic analysis of EuMV-Jal led to the discovery of a subgroup of SLCV clade viruses that contain in

Efficacy and immunogenicity of live-attenuated human rotavirus vaccine in breast-fed and formula-fed European infants.

Science.gov (United States)

Vesikari, Timo; Prymula, Roman; Schuster, Volker; Tejedor, Juan-C; Cohen, Robert; Bouckenooghe, Alain; Damaso, Silvia; Han, Htay Htay

2012-05-01

Rotavirus is the main cause of severe gastroenteritis and diarrhea in infants and young children less than 5 years of age. Potential impact of breast-feeding on the efficacy and immunogenicity of human rotavirus G1P[8] vaccine was examined in this exploratory analysis. Healthy infants (N = 3994) aged 6-14 weeks who received 2 doses of human rotavirus vaccine/placebo according to a 0-1 or 0-2 month schedule were followed for rotavirus gastroenteritis during 2 epidemic seasons. Rotavirus IgA seroconversion rate (anti-IgA antibody concentration ≥ 20 mIU/mL) and geometric mean concentrations were measured prevaccination and 1-2 months post-dose 2. Vaccine efficacy against any and severe rotavirus gastroenteritis was analyzed according to the infants being breast-fed or exclusively formula-fed at the time of vaccination. Antirotavirus IgA seroconversion rate was 85.5% (95% confidence interval [CI]: 82.4-88.3) in breast-fed and 89.2% (95% CI: 84.2-93) in exclusively formula-fed infants; geometric mean concentrations in the respective groups were 185.8 U/mL (95% CI: 161.4-213.9) and 231.5 U/mL (95% CI: 185.9-288.2). Vaccine efficacy was equally high in breast-fed and exclusively formula-fed children in the first season but fell in breast-fed infants in the second rotavirus season. During the combined 2-year efficacy follow-up period, vaccine efficacy against any rotavirus gastroenteritis was 76.2% (95% CI: 68.7-82.1) and 89.8% (95% CI: 77.6-95.9) and against severe rotavirus gastroenteritis 88.4% (95% CI: 81.6-93) and 98.1% (95% CI: 88.2-100) in the breast-fed and exclusively formula-fed infants, respectively. The difference in immunogenicity of human rotavirus vaccine in breast-fed and exclusively formula-fed infants was small. Vaccine efficacy was equally high in breast-fed and exclusively formula-fed children in the first season. Breast-feeding seemed to reduce slightly the efficacy in the second season.

repDNA: a Python package to generate various modes of feature vectors for DNA sequences by incorporating user-defined physicochemical properties and sequence-order effects.

Science.gov (United States)

Liu, Bin; Liu, Fule; Fang, Longyun; Wang, Xiaolong; Chou, Kuo-Chen

2015-04-15

In order to develop powerful computational predictors for identifying the biological features or attributes of DNAs, one of the most challenging problems is to find a suitable approach to effectively represent the DNA sequences. To facilitate the studies of DNAs and nucleotides, we developed a Python package called representations of DNAs (repDNA) for generating the widely used features reflecting the physicochemical properties and sequence-order effects of DNAs and nucleotides. There are three feature groups composed of 15 features. The first group calculates three nucleic acid composition features describing the local sequence information by means of kmers; the second group calculates six autocorrelation features describing the level of correlation between two oligonucleotides along a DNA sequence in terms of their specific physicochemical properties; the third group calculates six pseudo nucleotide composition features, which can be used to represent a DNA sequence with a discrete model or vector yet still keep considerable sequence-order information via the physicochemical properties of its constituent oligonucleotides. In addition, these features can be easily calculated based on both the built-in and user-defined properties via using repDNA. The repDNA Python package is freely accessible to the public at http://bioinformatics.hitsz.edu.cn/repDNA/. bliu@insun.hit.edu.cn or kcchou@gordonlifescience.org Supplementary data are available at Bioinformatics online. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Application of rep-PCR as a molecular tool for the genetic diversity ...

African Journals Online (AJOL)

admin

2016-02-17

Feb 17, 2016 ... leaf tissues were ground with a mortar and pestle to a fine powder using liquid nitrogen. Five grams of the leaves ... Amplification was performed in a thermal cycler (Eppendorf, Germany) PCR machine. ... extraction kit (Qiagen, Hilden, Germany) and cloned into the PCR cloning vector, pMiniT Vector (NEB ...

La función administrativa ejercida por el Congreso de la República

OpenAIRE

Ortiz, Maribel

2017-01-01

La función administrativa en Colombia, no sólo es desarrollada por la Rama Ejecutiva del poder público, sino que también es ejercida por la Rama Legislativa para el cumplimiento de sus fines. Es a partir de la Constitución de 1991, cuando en desarrollo del mandato Constitucional y de las facultades que tiene el Congreso de la República, se expidieron dos normativas: la ley 3ª de 1992 (por la cual se expiden normas sobre las Comisiones del Congreso de Colombia y se dictan otras disposici...

La radio en la segunda república española: sociedad y publicidad

OpenAIRE

Sebastián Morillas, Sebastián

2006-01-01

El artículo versa sobre la evolución del medio radio durante la II República Española a la vez que analiza la publicidad radiofónica de la época y sus efectos en una sociedad a punto de dividirse en dos bandos enfrentados en armas. This article is about the evolution of the radio broadcast during the Second Spanish Republic. It also analyses the radio commercials in that time, and how this commercials had a great influence on Spanish society, which was close to a civil war.

Germany, Russia, and energy

International Nuclear Information System (INIS)

Paillard, Christophe Alexandre

2007-01-01

This article first recalls and comments the objectives defined in March 2007 by the European Council in terms of energy to struggle against climate change. These objectives relate to the reduction of greenhouse gas emissions, to renewable energies, to energy saving, and to the share of biofuels. It outlines that Germany worries about the political situation in Russia and the capacities of this country to supply Europe with hydrocarbons. Figures related to consumption of primary energy and to sources of production of electricity in Germany show that Germany is facing an increased energy dependency. The issues related to the relationship between the EU and Russia in the field of energy are further discussed, notably from the German point of view, but also from a European point of view as the EU expects a stronger reaction of Germany in front of the Russian situation

Drugs in East Germany.

Science.gov (United States)

Dressler, J; Müller, E

1997-09-01

Germany was divided into two parts after World War II. The closed border and a nonconvertible currency in the Eastern part were the factors that did not allow a drug market to develop. Alcohol and medicaments were used as substitute drugs. Since Germany was reunified 5 years ago, there are now the same conditions prevailing for the procurement and sale of drugs in East Germany as there are in the Western German states. This report describes the current state of drug traffic, especially in Saxony, under the new social conditions.

Feature selection and data sampling methods for learning reputation dimensions: The University of Amsterdam at RepLab 2014

NARCIS (Netherlands)

Gârbacea, C.; Tsagkias, M.; de Rijke, M.

2014-01-01

We report on our participation in the reputation dimension task of the CLEF RepLab 2014 evaluation initiative, i.e., to classify social media updates into eight predefined categories. We address the task by using corpus-based methods to extract textual features from the labeled training data to

La República Holandesa y su posición en el contexto colonial americano después de 1713

Directory of Open Access Journals (Sweden)

Crespo Solana, Ana

2015-06-01

Full Text Available During the War of Spanish Succession, the Dutch Republic fought alongside the Austrians and their allies against the Bourbon party. Still, and in spite of its alliance with England, the treaties of Utrecht did not leave the Dutch Republic in a good position. In this article, these treaties’ consequences for the commercial and colonial Dutch expansion in the Atlantic world are analyzed.Durante la guerra de Sucesión española, la República Holandesa luchó junto al bloque aliado austracista contra la opción borbónica. Sin embargo, y a pesar de su alianza con Inglaterra, la República Holandesa no salió bien restablecida de los tratados de Utrecht. En este artículo se analizarán las consecuencias que estos tratados tuvieron para la expansión comercial y colonial de Holanda en el Atlántico.

Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI+

Directory of Open Access Journals (Sweden)

Fátima eGasset-Rosa

2015-04-01

Full Text Available The yeast translation termination factor Sup35p, by aggregating as the [PSI+] prion, enables ribosomes to read-through stop codons, thus expanding the diversity of the Saccharomyces cerevisiae proteome. Yeast prions are functional amyloids that replicate by templating their conformation on native protein molecules, then assembling as large aggregates and fibers. Prions propagate epigenetically from mother to daughter cells by fragmentation of such assemblies. In the N-terminal prion-forming domain, Sup35p has glutamine/asparagine-rich oligopeptide repeats (OPRs, which enable propagation through chaperone-elicited shearing. We have engineered chimeras by replacing the polar OPRs in Sup35p by up to five repeats of a hydrophobic amyloidogenic sequence from the synthetic bacterial prionoid RepA-WH1. The resulting hybrid, [REP-PSI+], i was functional in a stop codon read-through assay in S. cerevisiae; ii generates weak phenotypic variants upon both its expression or transformation into [psi-] cells; iii these variants correlated with high molecular weight aggregates resistant to SDS during electrophoresis; and iv according to fluorescence microscopy, the fusion of the prion domains from the engineered chimeras to the reporter protein mCherry generated perivacuolar aggregate foci in yeast cells. All these are signatures of bona fide yeast prions. As assessed through biophysical approaches, the chimeras assembled as oligomers rather than as the fibers characteristic of [PSI+]. These results suggest that it is the balance between polar and hydrophobic residues in OPRs what determines prion conformational dynamics. In addition, our findings illustrate the feasibility of enabling new propagation traits in yeast prions by engineering OPRs with heterologous amyloidogenic sequence repeats.

Germany, Pacifism and Peace Enforcement

DEFF Research Database (Denmark)

Dalgaard-Nielsen, Anja

This book is about the transformation of Germany's security and defence policy in the time between the 1991 Gulf War and the 2003 war against Iraq. It traces and explains the reaction of Europe's biggest and potentially most powerful country to the ethnic wars of the 1990s, the emergence of large...... the 1990s. The book debates the implications of Germany's transformation for Germany's partners and neighbours, and explains why Germany said ‘yes’ to the war in Afghanistan, but ‘no’ to the Iraq War. Based on a comprehensive study of the debates of the German Bundestag and actual German policy responses...

La europeización de la República de Moldova: un camino sinuoso e incierto hacia la integración europea

Directory of Open Access Journals (Sweden)

Aurelia Dercaci

2014-01-01

Full Text Available Después de la proclamación de la independencia en 1991, la República de Moldova (RM ha declarado su firme determinación de emprender su camino hacia Europa, a la que se siente identificada culturalmente. Aunque en las declaraciones y documentos adoptados el Estado nunca ha renunciado a este objetivo, ciertas acciones de sus líderes políticos parecen contradecir dicho compromiso. El trabajo tiene como objetivo analizar el proceso de evolución de la República de Moldova a la Unión Europea (UE, los compromisos asumidos por ambos y su cumplimiento. Además, voy a comparar los progresos realizados por Ucrania y RM hacia el acercamiento a la Unión Europea en los últimos años. Hace algunos años, Ucrania fue el país oriental con la perspectiva fundamental de la futura integración en la UE debido a sus cambios democráticos, hoy República de Moldova ha demostrado ser capaz de hacer más progresos en la promoción de la democracia y la aplicación de las reformas de gobernanza que Ucrania. Por otro lado, la relación entre la RM y la UE sigue siendo influenciada por las medidas adoptadas por la Federación de Rusia en la región donde todavía tiene influencia significativa, y tratar de mantener su presencia. Una de las herramientas fuertes de la influencia es la dependencia del suministro de energía y su falta de diversificación. El conflicto sin resolver de Transnistria es otro factor determinante de la falta de certeza en el proceso de europeización de la RM. El trabajo tiene como objetivo analizar la eficiencia de la europeización de la República de Moldova a través de la Política de Vecindad Europea, utilizando un método combinado constructivista y racionalista.

International comparison of the chemical assay of uranium and thorium in THTR fuel for safeguards purposes

International Nuclear Information System (INIS)

Thiele, D.; Brodda, B.G.; Mainka, E.; Goergenyi, T.; Kuhn, E.; Aigner, H.

1983-01-01

The Thorium High Temperature Prototype Reactor (THTR) at Schmehausen (Fed. Rep. Germany) burns a (Th, U)O 2 nuclear fuel using 93% enriched uranium. This material is particularly safeguards sensitive. An interlaboratory test has been completed on the heavy metal determination in BISO type (Th, U)O 2 particles. The laboratories involved were BAM, KFA, KfK, NUKEM and SAL (IAEA). The modified Davies and Gray titration was applied for uranium, oxalate precipitation followed by ignition to ThO 2 and gravimetry for thorium. The exercise allowed an estimate to be made of the various error components: the results indicate that the sampling techniques applied in this experiment ensure a representativity of the sample of 0.05% or better. The precision of the measurements (1sigma) is better than or equal to 0.15%. Assuming the overall means are the true values, the accuracy of the methods is better than or equal to 0.1%. This fulfills safeguards requirements. (orig.)

Utility experience in reactor noise analysis in German LWRs

International Nuclear Information System (INIS)

Schuette, A.; Weingarten, J.; Wach, D.

1988-01-01

Reactor noise analysis has a long history in Fed. Rep. of Germany. Since the early 60ies it was directed to early fault, malfunction and anomaly detection in nuclear power plants. When successful diagnoses showed the high potential and benefits including economic and safety aspects, also the utilities began to have a vivid concern in application of the developed methods and systems. The know-how transfer from specialized teams to the onsite personnel as well as the development of more ''intelligent'' online systems are important present and future tasks for further improvement of their efficiency. The diagnostic group of GRS is active in both fields and has close cooperation with several utilities to achieve these objectives. Modern signal processing equipment and access to a comprehensive knowledge base stored in data banks are provided by the data analysis center of GRS. The available capabilities are described and examples of analysis results within the cooperation utilities/GRS are given. (author)

Weimar Germany

DEFF Research Database (Denmark)

Reckendrees, Alfred

2015-01-01

The Weimar Republic is analysed within the concept of limited and open access orders. Before World War I, Imperial Germany had developed into a mature limited access order with rule of law and open economic access but lack of competition in politics. After World War I and inflation, Weimar Germany...... developed toward an open access order; open access was not, however, sustainable and collapsed in 1930–31. This case of a failed open access order suggests refining the framework of limited and open access orders in further work. It shows that the political process of “creative destruction” might result...

CoQ10 plasmatic levels in breast-fed infants compared to formula-fed infants.

Science.gov (United States)

Compagnoni, G; Giuffrè, B; Lista, G; Mosca, F; Marini, A

2004-01-01

Coenzyme Q10 has been recognized as an important antioxidant factor besides its main role in bioenergetic metabolism. CoQ10 tissue levels depend both on exogenous dietetic intake and on endogenous biosynthesis, as this compound can be partly synthesized in human cells. Q10 plasma levels reflect the tissue content of the coenzyme and can be used to evaluate the presence of this compound in the human organism. Aim of the study was to measure CoQ10 plasmatic levels in a newborn breast-fed population and to compare them to CoQ10 levels in a newborn formula-fed population in order to verify whether changes in CoQ10 plasmatic contents could be related to a different dietetic intakes. We measured CoQ10 plasmatic levels in 25 healthy term neonates with different dietetic intakes: 15 breast-fed and 10 bottle-fed with a common infant formula. These infants were evaluated prospectively during the first month of life. The analyses were performed on the mothers' blood samples and cord blood samples at the time of delivery, then on infants at 4 and 28 days of age. Our results showed markedly reduced Q10 levels in cord blood samples compared to maternal Q10 plasmatic levels at the time of delivery, suggesting placental impermeability towards this molecule or increased fetal utilization during labor and delivery. At 4 days of age Q10 levels had increased in both groups of neonates, but significantly more in breast-fed infants compared to formula-fed babies (p <0.05). At 4 weeks of age no significant changes occurred in breast-fed infants, while values increased significantly in formula-fed infants (p <0.05). The content of Q10 in breast milk samples was lower than in infant formula. The results of this study show that CoQ10 plasmatic levels are at least partly influenced by the exogenous dietetic supply.

Genotipificación de aislamientos de Bartonella bacilliformis por amplificación de elementos repetitivos mediante el uso de REP-PCR y ERIC-PCR

Directory of Open Access Journals (Sweden)

Carlos Padilla R

2003-07-01

Full Text Available Objetivos: Genotipificar los aislamientos de Bartonella bacilliformis a través de la amplificación de elementos repetitivos mediante el uso de ERIC-PCR y REP-PCR, y determinar si existe variabilidad genética entre aislamientos de varias zonas endémicas. Materiales y Métodos: Se evaluaron mediante el uso del ERIC-PCR y REP-PCR 17 aislamientos de B. bacilliformis de Lima, Cusco y Ancash. Los aislamientos fueron realizados durante los años 1998 y 1999. Para el análisis de los patrones de bandas se usó el software GelCompar 4,0. Resultados: Fueron identificados en los 17 aislamientos 10 genotipos. Los genotipos D, E y H fueron detectados en Cusco; mientras que los genotipos B, C, G, J e I en Lima; y el genotipo F en Ancash. Conclusiones: Nuestros resultados sugieren que REP-PCR y ERIC-PCR son métodos útiles para genotipificar aislamientos de B. bacilliformis. La variabilidad genética debe ser tomada en cuenta en estudios epidemiológicos y clínicos de Bartonelosis; así como el desarrollo de nuevas técnicas diagnósticas y de vacunas.

Exocrine pancreatic secretion is stimulated in piglets fed Fish oil compared with those fed Coconut Oil or Lard

DEFF Research Database (Denmark)

Hedemann, Mette Skou; Pedersen, Asger Roer; Engberg, Ricarda M.

2001-01-01

An experiment was conducted to study the effect of feeding diets containing fat sources with different fatty acid composition (fish oil, coconut oil or lard, 10 g/100 g diet) on exocrine pancreatic secretion in piglets after weaning. A total of 16 barrows were weaned at 4 wk of age; 3 d later...... the coconut oil or lard diets. The output [U/(h. kg(0.75))] of lipase was higher in piglets fed fish oil than in piglets fed lard or coconut oil. The output of colipase was greater in piglets fed fish oil and coconut oil than in those fed lard. The dietary treatments did not affect the output of carboxylester...... hydrolase. The output of trypsin was significantly lower in piglets fed lard than in piglets fed fish oil or coconut oil diets and the output of carboxypeptidase B was greater in those fed the fish oil diet. Protein, chymotrypsin, carboxypeptidase A, elastase and amylase outputs did not differ among...

Cegelec Germany

International Nuclear Information System (INIS)

2011-01-01

Cegelec is a group of companies acting internationally and one of Europe's biggest plant engineering firms in the fields of power generation and distribution with the focus on engineering and technical services. Cegelec's competences in Germany are mainly in planning, installation and maintenance of plants and facilities in all key industries and for public clients. The main areas of activity are industry, infrastructure and power, for which Cegelec offers comprehensive project and service work. While the Industry business area covers chemistry, steel, paper, automotive, re-engineering, and mining industries, Cegelec's Infrastructure unit performs services to airports, in tunnel construction, for railways and waterways. The Power market segment comprises gas, refuse incineration, power supply, sugar, power plants, and nuclear final storage. Cegelec is represented in Germany on roughly 30 locations with a staff of 1,700. The origins of Cegelec are in Germany, i.e. in AEG founded 1896. The Plant and Automation Technology sector was divested in 1996 and moved to Alstom where, in 2001, a management buyout led to the independent Cegelec group of companies. When the strategic partnership between Qatari Diar and Vinci took shape, Cegelec became a subsidiary of the Vinci group in April 2010. (orig.)

Elecciones 2016 en República Dominicana: Características, desafíos y retos desde la perspectiva electoral

Directory of Open Access Journals (Sweden)

Roberto Rosario Márquez

2015-01-01

Full Text Available Expone la reforma electoral del año 2010, los aspectos importantes que se presentaron en las elecciones de 2012 y los retos que la Junta Central Electoral de la República Dominicana enfrenta en la organización y administración del proceso electoral del año 2016

Germany at CERN

CERN Document Server

2001-01-01

The Eighth Exhibition of German Industry, "Germany at CERN" started this week and offers German companies the opportunity to establish professional contacts with CERN. From left to right in the foreground: Maximilian Metzger (BMBF), Bettinna Schöneseffen (BMBF), Karl-Heinz Kissler (SPL division leader), Horst Wenninger, and Hans Hoffman. Behind and to the right of Karl-Heinz Kissler is His Excellency Mr Walter Lewalter, Ambassador and permanent representative of Germany to the UN office in Geneva.

RePS: a sequence assembler that masks exact repeats identified from the shotgun data

DEFF Research Database (Denmark)

Wang, Jun; Wong, Gane Ka-Shu; Ni, Peixiang

2002-01-01

We describe a sequence assembler, RePS (repeat-masked Phrap with scaffolding), that explicitly identifies exact 20mer repeats from the shotgun data and removes them prior to the assembly. The established software is used to compute meaningful error probabilities for each base. Clone......-end-pairing information is used to construct scaffolds that order and orient the contigs. We show with real data for human and rice that reasonable assemblies are possible even at coverages of only 4x to 6x, despite having up to 42.2% in exact repeats. Udgivelsesdato: 2002-May...

Leptospirosis porcina: prevalencia serológica en establecimientos productores de la República Argentina

OpenAIRE

Petrakovsky M, Jessica; Tinao, Julio; Esteves M, Jorge

2013-01-01

RESUMENObjetivo. Detectar la presencia de anticuerpos contra Leptospira sp en cerdos que no presentaban sintomatología clínica, pertenecientes a establecimientos de producción porcina ubicados en todo el territorio de la República Argentina. Materiales y métodos. La asignación de predios y muestras se realizó en forma proporcional a los registrados en cada provincia a lo largo de todo el país. En total se estudiaron 1.524 predios, de los cuales se tomaron 19.872 muestras de suero y en la prim...

El Gobierno de la República en el exilio : crónica de un imposible retorno

Directory of Open Access Journals (Sweden)

Xavier Flores

2001-01-01

Full Text Available El triunfo de los aliados en la Segunda Guena Mundial hizo que los republicanos españoles exiliados en 1939 concibiesen esperanzas de un inmediato retomo de la República a su país con el apoyo aliado. Con esta idea se reconstituyeron las instituciones de la República Española en el exilio en México D. R, en agosto de 1945. En este artículo se analiza el proceso de esa reconstitución y los sucesivos gobiernos que se sucedieron hasta la disolución de las instituciones en junio de 1977, después de un imposible retorno.The victory of the salles in the Second World war did that the Spanish republicans exiled in 1939 were conceiving hopes ofan immediate return ofthe Republic to his(its country with the allied support. With this idea there were re-constituted the institutions of the Spanish Republic in the exile in México D.F., in August, 1945. In this article there are analyzed the process of this reconstitution and the successive governments that happened up to the dissolution of the institutions in June, 1977, afíer impossible I come back.

Dental tourism from Switzerland to Germany.

Science.gov (United States)

Gheorghe, Raluca; Zürcher, Andrea; Filippi, Andreas

In recent years the topic of dental tourism has increasingly come into focus of dentists and patients. In the present study an attempt was made to find out, why patients from a restricted region travel to Germany for dental care. In five German dental clinics located in the border area between Switzerland and Germany, 272 women and 236 men ranging in age from 5 to 94 years, who had undergone at least one dental treatment in Germany, were questioned concerning the reasons for their visits. The interviews took place within a period of 6 months and relied on a questionnaire to collect data regarding sociodemographic features and patient behavior. In comparison to residents of Germany, patients residing in Switzerland took on considerably longer travel distances for the dental visit, in some cases more than 50km (9.7%). For patients residing in Switzerland the technical equipment of the practice was more important (pSwitzerland (95.6%) confirmed that dental treatments in Germany were cheaper and that additional family members also came to Germany for dental care (65.0%).

Estudo de práticas midiáticas a partir do produto: o jogo de espelhos de Profissão Repórter

Directory of Open Access Journals (Sweden)

Mirian Meliani

2013-06-01

Full Text Available Analisar todas as nuances do discurso e das práticas adotadas pelo programa jornalístico Profissão Repórter, produzido pela Rede Globo, foi a tarefa realizada por jornalistas, pro- fessores e pós-graduandos ligados ao grupo de pesquisa MidiAto – Grupo de Estudos de Linguagem: Práticas Midiáticas, da Escola de Comunicações e Artes (ECA/USP. O resultado é uma exposição, bastante ampla, dos limites, das contradições e do papel desempenhado pelo programa na grade da emissora líder de audiência no Brasil, transcrita no livro Profissão Repórter em diálogo por meio de dezessete artigos.

Germany: Management of decommissioning waste in Germany

International Nuclear Information System (INIS)

Borrmann, F.; Brennecke, P.; Koch, W.; Kugel, K.; Steyer, S.

2007-01-01

Over the past two decades, Germany has gained a substantial amount of experience in the decommissioning of nuclear facilities of different types and sizes. Many research reactors and all prototype nuclear power plants, as well as a few larger nuclear power plants and fuel cycle facilities, are currently at varying stages of decommissioning. Several facilities have been fully dismantled and the sites have been cleared for reuse. The decommissioning projects comprise 18 power and prototype reactors, 33 research reactors and 11 fuel cycle facilities which are being or have been decommissioned. In the future, further nuclear power plants will be shut down and decommissioned in accordance with Germany?s energy policy to phase out the use of nuclear power for commercial electricity generation as given in the April 2002 amendment of the Atomic Energy Act. Radioactive waste, from operations as well as from decommissioning activities, is to be conditioned in such a way as to comply with the waste acceptance requirements of a repository. In Germany, all types of radioactive waste (i.e., short-lived and long-lived) are to be disposed of in deep geological formations. A distinction is being made for heat generating waste (i.e., high level waste) and waste with negligible heat generation (i.e., low level and intermediate level waste). Radioactive decommissioning waste is waste with negligible heat generation. Waste acceptance requirements of a repository are of particular importance for the conditioning of radioactive waste, including decommissioning waste. The waste acceptance requirements, as they resulted from the Konrad licensing procedure, are being applied by the waste generators for the conditioning of decommissioning waste. Compliance with these requirements must be demonstrated through the waste package quality control, even if the waste will be disposed of in the future. In 2002 the Konrad repository was licensed for the disposal of all types of waste with negligible

A Primeira República Portuguesa (1910-1926: partidos e sistema político

Directory of Open Access Journals (Sweden)

Baiôa, Manuel

2014-04-01

Full Text Available For historical, organisational, clientelist, violent and constitutional reasons the Portuguese Republican Party became the dominant party in the political system of the Portuguese First Republic (1910-1926. The opposition felt alternation via elections would be difficult to achieve so resorted to violent and unconstitutional practices to reach government. The Portuguese political parties modernised themselves in this period, but failed to turn into mass parties. In major cities they acted as a cadre party and in the rural area as a party of notables. The First Republic failed to take solid steps to democratise the political system were And Portugal remained tied to the liberal and elitist tradition of the nineteenth century, although in a republican version.El Partido Republicano Portugués se convirtió en el partido dominante del sistema político de la Primera República Portuguesa (1910-1926 debido a causas históricas, organizacionales, clientelistas, violentas y constitucionales. La oposición sentía que difícilmente conseguiría la alternancia política a través de elecciones, y por lo tanto, recurre a prácticas violentas e inconstitucionales para llegar al gobierno. Los partidos políticos portugueses se modernizaron en este período, pero no se convirtieron en partidos de masas. En las principales ciudades actuaban como partidos de cuadros y en las zonas rurales como partidos de notables. Durante la Primera República no se dieron pasos consistentes para democratizar el sistema político. Portugal se mantuvo ancorado a la tradición liberal y elitista del siglo XIX, aunque en una versión republicana.

O leitor e as ‘fronteiras’ do universo fantástico na obra A República 3000, de Menotti del Picchia = The reader and the ‘borders’ of the fantastic universe in the book A República 3000, from Menotti del Picchia

Directory of Open Access Journals (Sweden)

Cristiano Mello de Oliveira

2012-01-01

Full Text Available No presente artigo pretendemos descortinar as relações entre os elementos fantásticos na obra A República 3000, do escritor Menotti del Picchia. Primeiramente iremos realizar uma breve recapitulação de alguns aspectos da literatura fantástica no Brasil. Posteriormente faremos recortes textuais, objetivando assim discutir aqueles que aproximem a linguagem com o universo fantástico. Tomaremos como referencial teórico os estudos de autores como Todorov e Carvalho. Também teceremos considerações sobre o comportamento do leitor diante dessa obra ímpar.This article aims to scrutinize the relationship of the fantastic elements in Menotti del Picchia’s work A República 3000. Firstly, we will briefly look at some aspects inherent to the Fantastic Literature in Brazil. Then we will select some excerpts whose language are closely related to the fantastic world. The theoretical framework draws on Todorov and Carvalho. We will also consider the possible reader’s degree of behavior in relation to the aforementioned masterpiece.

[Fostering of health economics in Germany].

Science.gov (United States)

Ulrich, V

2012-05-01

Health economics is now well established in Germany with the aim to apply economic tools to answer problems in health and health care. After a short review of the international development of health economics and the development in Germany in particular, the article looks at selected recent topics of health economic analysis in Germany (economic evaluation, industrial economics, health and education).

The Lincoln Image in Germany

Directory of Open Access Journals (Sweden)

Jörg Nagler

2016-05-01

Full Text Available This essay investigates the enduring fascination with the sixteenth President of the United States in Germany. In general, his legacy and its evaluation changed in relation to the determinate historical contexts, beginning with the monarchial system, extending through the Weimar Republic, the Third Reich, and now the Federal Republic of Germany. Certain social and political individuals/groups in Germany used the image and iconography of Lincoln as a projection screen to support their own political objectives. Although there were always multiple layers of Lincoln representations in Germany, the dominant images were: the national unifier, the libertarian universalist, the emancipator, the defender of moral values, the modernizer, the democrat who used the power of the democratic state, the egalitarian self-made man from humble origins, and the defender of social justice and workingmen’s rights.

International design competition. Formula student Germany; Internationaler Konstruktionswettbewerb. Formula Student Germany

Energy Technology Data Exchange (ETDEWEB)

Liebl, Johannes; Siebenpfeiffer, Wolfgang (eds.)

2011-11-15

Within the International Design Competition 2011 at the Hockenheimring (Federal Republic of Germany) the following contributions were presented: (1) Formula Student Germany - Experience the Future (Tim Hannig); (2) Live at the Hockenheimring 2011; (3) Cutaway Model of the FSC Winning Car - The GFR11c by the Global Formula Racing Team of the DHBW Ravensburg; (4) Formula Student Racecar with Selective Cylinder Deactivation (Alexander Titz); (5) Construction of a crankshaft for the RS11 (Stefan Buhl); (6) The Wheel Design of the ARG 11 (Megan Rotondo); (7) Cutaway Model of the FSE Winning Car - The DUT11 by the DUT Racing Team of the Delft University of Technology; (8) Formula Student Electric - E-Scrutineering (Ann-Christin Bartoelke); (9) Development of an E-motor for Formular Student Electric (Urs Leuthold); (10) The Battery Management System of the FHWT04e (Andreas Hagemeyer); (11) Overall Results 2011 at a Glance; (12) Show your Colours; (13) Formula Student Germany visiting China (Alia Pierce).

Reversing course: Germany`s response to the challenge of transboundary air pollution

Energy Technology Data Exchange (ETDEWEB)

Sprinz, D.F.; Wahl, A.

1998-03-01

Perhaps like no other country, Germany has radically changed its policies towards regulating air pollution in the European context. Acting originally as a dragger in the 1970s to regulate transboundary air pollutants due to pessimism about the relationship between causes and effects, Germany responded very decisively to its own damage assessment in the early 1980s. In particular the adverse effects to forests (`Waldsterben` or forest decline) led to the formulation of strict air pollution regulations in the domestic context, efforts to spread the regulatory system within the European Union, and activities within the United Nations Economic Commission for Europe to foster stronger, continent-wide emission reductions. Using three conceptual models (rational actor, domestic politics, and social learning), we show that Germany deviated strongly from the ideal policy cycle consisting of (i) domestic policy formulation, (ii) international negotiations, as well as (iii) implementation and compliance with the provisions of international environmental agreements. Both national policy-making as well as partial implementation have been well on the way towards compliance even before Germany entered international negotiations on substantive protocols. Therefore, one may conclude from this country study that push countries may use the results of their national policy processes to influence the policy of other countries. (orig.)

Rediseño y fabricación de una impresora 3D RepRap.

OpenAIRE

Huertas González, Joan

2014-01-01

El objetivo principal de este proyecto es conseguir las habilidades necesarias para fabricar una impresora 3D del tipo Rep Rap, una tipología de impresoras Open source. Una vez conseguido este objetivo se rediseñan piezas de la propia impresora con el objetivo de mejorar el diseño actual. Se plantea el proyecto como iniciación al mundo de la impresión 3D y de los materiales plásticos con los que se puede trabajar, PLA, HDPE, ABS o NYLON. Se instruye al lector para que tambié...

Macau no Contexto da Estratégia de Integração da República Popular da China no Mercado Mundial

OpenAIRE

Murteira, Mário

1994-01-01

Série II Especulação sobre o futuro de Macau perante a forte estratégia de intergração da República Popular da China no mercado mundial (com o desempenho de um papel influente por parte de Macau e Taiwan).

Uranium mining in Eastern Germany

International Nuclear Information System (INIS)

Sauer, H.D.

1990-01-01

A problem which simply does not exist in Western Germany is the uranium mining in the South of Eastern Germany (SDAG Wismuth). The cleaning up and control measure which are urgently needed will be a task for more than one generation. (orig./HP) [de

Nuclear energy in Germany

International Nuclear Information System (INIS)

1999-01-01

Since September 1998 the Federal Government formed by a Red/Green Coalition declared its goal: irreversible phase out of nuclear power plants. The first attempt to stop reprocessing as well as the first attempt to change nuclear law failed. The present situation is as follows: existing nuclear power plants operate in a most satisfying way producing 170 TWh/a. i.e. 35% of total production; transport license is not granted; no new NPP is planned, but Germany will participate in the French European Power Reactor (EPR) project. Concerning fast reactors, no industrial activities exist in Germany. There is no intention to build a facility, but Germany participates in the European CAPRA project. Existing research items are related to neutronics, safety analysis, irradiation experiment TRABANT, accelerator driven systems, thermohydraulics, safety

Bioreactor production of recombinant herpes simplex virus vectors.

Science.gov (United States)

Knop, David R; Harrell, Heather

2007-01-01

Serotypical application of herpes simplex virus (HSV) vectors to gene therapy (type 1) and prophylactic vaccines (types 1 and 2) has garnered substantial clinical interest recently. HSV vectors and amplicons have also been employed as helper virus constructs for manufacture of the dependovirus adeno-associated virus (AAV). Large quantities of infectious HSV stocks are requisite for these therapeutic applications, requiring a scalable vector manufacturing and processing platform comprised of unit operations which accommodate the fragility of HSV. In this study, production of a replication deficient rHSV-1 vector bearing the rep and cap genes of AAV-2 (denoted rHSV-rep2/cap2) was investigated. Adaptation of rHSV production from T225 flasks to a packed bed, fed-batch bioreactor permitted an 1100-fold increment in total vector production without a decrease in specific vector yield (pfu/cell). The fed-batch bioreactor system afforded a rHSV-rep2/cap2 vector recovery of 2.8 x 10(12) pfu. The recovered vector was concentrated by tangential flow filtration (TFF), permitting vector stocks to be formulated at greater than 1.5 x 10(9) pfu/mL.

Ordem e Progresso: Augusto Comte e as influências do Positivismo na educação das mulheres na Primeira República brasileira

Directory of Open Access Journals (Sweden)

Loraine Lopes de Oliveira

2018-04-01

Full Text Available O presente artigo tem como objetivo apresentar uma reflexão acerca da influência do Positivismo na educação das mulheres no contexto da Primeira República brasileira (1889-1930, também chamada de República Velha. Faz-se uma breve abordagem inicial a respeito de Augusto Comte e o surgimento da filosofia positivista e posteriormente se discorre sobre a influência do Positivismo na educação das mulheres, a qual era vista como um elemento chave para a concretização da nova sociedade que se projetava, para o progresso e a modernização. A pesquisa tem caráter bibliográfico e fundamenta-se nos pressupostos teóricos do materialismo histórico-dialético, que busca compreender os fenômenos sociais e históricos a partir da existência material dos homens. A discussão prioriza a relação da educação com os fatores econômicos, políticos e sociais, já que se compreende que o objeto de pesquisa não pode ser entendido como uma situação isolada de seu contexto histórico. Palavras-chave: Positivismo. Primeira República Brasileira. Educação das mulheres.   Order and Progress: Augusto Comte and the influences of Positivism in the education of women in the First Brazilian Republic ABSTRACT The present article aims to present a reflection on the influence of positivism in the education of women in the context of the First Brazilian Republic (1889-1930, also called the Old Republic. A brief initial approach is given to Augusto Comte and the emergence of the positivist philosophy and later it talks about the influence of positivism in the education of women, a qualitative perspective as a key element for a concretization of the new society which was projected, for progress and modernization. The research has a bibliographic character and is based on the theoretical assumptions of historical-dialectical materialism, which seeks social and historical phenomena from the material reality of men. The discussion prioritizes the relationship

UNITED STATES AND GERMAN BILATERAL AGREEMENT ON REMEDIATION OF HAZARDOUS WASTE SITES

Science.gov (United States)

The U.S. Environmental Protection Agency (EPA) and Germany's Bundesministerium fur Forschung und Technologie (BMFT) are involved in a collaborative effort called the U.S. and German Bilateral Agreement on Remediation of Hazardous Waste Sites. he purpose of this interim status rep...

Tokamak-FED plasma-engineering assessments

International Nuclear Information System (INIS)

Peng, Y.K.M.; Lyon, J.F.; Rutherford, P.H.

1981-01-01

A wide range of plasma assumptions and scenarios has been examined for the current US tokamak FED concept, which aims to provide a controlled, long pulse (approx. 100 s) burning plasma with an energy amplification of greater than or equal to 5, a fusion power of 180 MW, and a neutron wall load of greater than or equal to 0.4 MW/m 2 . The results of the assessment suggest that the current FED baseline parameters of R = 5.0 m, B/sub t/ = 3.6 T, a = 1.3 m, b = 2.1 m (D-shape), and I/sub p/ = 5.4 MA are appropriate in reaching the above plasma performance, despite uncertainties in several plasma physics areas, such as confinement scaling, achievable beta, impurity control, etc. To enhance the probability of achieving fusion ignition and to provide some margin against a short fall in our physics projections in FED, a limited operating capability at B/sub t/ = 4.6 T and I/sub p/ = 6.5 MA is incorporated. Various other options and remedies have also been assessed aiming to alleviate the impact of the uncertainties on the FED design concept. These approaches appear promising because they can be studied within the current fusion physics program and may lead to drastically more cost-effective FED concepts

West-East migration in Germany since 1990

OpenAIRE

Beck, Grit

2011-01-01

Not only did 2.5 million people migrate from East Germany to West Germany between 1991 and 2006, 1.5 million people also moved from West to East Germany. This counter-current movement took placed largely unnoticed by the public and researchers alike. This paper uses both quantitative and qualitative data to first of all examine how the population structure in the New Länder has changed as a result of interregional migration between Länder in East and West Germany. It goes on to study the moti...

FED-A, an advanced performance FED based on low safety factor and current drive

International Nuclear Information System (INIS)

Peng, Y.K.M.; Rutherford, P.H.

1983-08-01

The FED-A study aims to quantify the potential improvement in cost-effectiveness of the Fusion Engineering Device (FED) by assuming low safety factor q (less than 2 as opposed to about 3) at the plasma edge and noninductive current drive (as opposed to only inductive current drive). The FED-A performance objectives are set to be : (1) ignition assuming International Tokamak Reactor (INTOR) plamsa confinement scaling, but still achieving a fusion power amplification Q greater than or equal to 5 when the confinement is degraded by a factor of 2; (2) neutron wall loading of about 1 MW/m 2 , with 0.5 MW/m 2 as a conservative lower bound; and (3) more clearly power-reactor-like operations, such as steady state

[Valitsusliidus olevad Reformierakond ning Isamaa ja Res Publica Liit on kavandatava koolireformi suhtes eri meelt] / Mailis Reps, Tiiu Kuurme, Karin Kütt

Index Scriptorium Estoniae

Reps, Mailis, 1975-

2010-01-01

Reformierakonna ettepaneku kohta jätta omavalitsustele õiguse otsustada, kas gümnaasium ja põhikool lahutatakse või jätkatakse ühendkooliga avaldavad arvamust riigikogu liige Mailis Reps, Tallinna Ülikooli dotsent Tiiu Kuurme ja Rannu keskkooli direktor Karin Kütt

Effective removal of a range of Ti/Ri plasmids using a pBBR1-type vector having a repABC operon and a lux reporter system.

Science.gov (United States)

Yamamoto, Shinji; Sakai, Ayako; Agustina, Vita; Moriguchi, Kazuki; Suzuki, Katsunori

2018-02-01

Ti and Ri plasmids of pathogenic Agrobacterium strains are stably maintained by the function of a repABC operon and have been classified into four incompatibility groups, namely, incRh1, incRh2, incRh3, and incRh4. Removal of these plasmids from their bacterial cells is an important step in determining strain-specific virulence characteristics and to construct strains useful for transformation. Here, we developed two powerful tools to improve this process. We first established a reporter system to detect the presence and absence of Ti/Ri plasmids in cells by using an acetosyringone (AS)-inducible promoter of the Ti2 small RNA and luxAB from Vibrio harveyi. This system distinguished a Ti/Ri plasmid-free cell colony among plasmid-harboring cell colonies by causing the latter colonies to emit light in response to AS. We then constructed new "Ti/Ri eviction plasmids," each of which carries a repABC from one of four Ti/Ri plasmids that belonged to incRh1, incRh2, incRh3, and incRh4 groups in the suicidal plasmid pK18mobsacB and in a broad-host-range pBBR1 vector. Introduction of the new eviction plasmids into Agrobacterium cells harboring the corresponding Ti/Ri plasmids led to Ti/Ri plasmid-free cells in every incRh group. The Ti/Ri eviction was more effective by plasmids with the pBBR1 backbone than by those with the pK18mobsacB backbone. Furthermore, the highly stable cryptic plasmid pAtC58 in A. tumefaciens C58 was effectively evicted by the introduction of a pBBR1 vector containing the repABC of pAtC58. These results indicate that the set of pBBR1-repABC plasmids is a powerful tool for the removal of stable rhizobial plasmids.

78 FR 53774 - Guide for the Evaluation of Alert and Notification Systems for Nuclear Power Plants, FEMA-REP-10...

Science.gov (United States)

2013-08-30

... available when FEMA REP-10 was first developed, such as smartphones and social media. Removes technical... proposed policy does not have the force or effect of law. FEMA seeks comment on the proposed policy, which... the force or effect of law. Authority: 6 U.S.C. 313-314a; Sec. 109, Pub. L. 96-295; E.O. 12148; 44 CFR...

Farming for Health: Aspects from Germany

OpenAIRE

Neuberger, Konrad; Stephan, Ingrid; Hermanowski, Robert; Flake, Albrecht; Post, Franz-Joseph; van Elsen, Thomas

2006-01-01

Until now, the term ‘Farming for Health’ is unknown in Germany but it would cover a wide spectrum of different kinds of social agriculture already existing in Germany, such as farms that integrate disabled people or drug therapy into their farming system, or farms that integrate children, pupils or older people. Relevant work in Germany is done in ‘Sheltered Workshops’, where supporting and healing powers of farming and gardening are used for disabled people with a diversity of work possibili...

Germany - an immigration country

OpenAIRE

Siebert, Horst

2003-01-01

Germany has about the same proportion of foreigners in its population as the United States, it is an immigration country. In a way, Germany has let immigration happen, but it did not really have an explicit immigration policy in the past. Now it has to make up its mind on its immigration policy in the future. The paper looks at the experience with immigration in the past, at the integration of foreigners and at the issues of immigration policy.

Assessing Success Factors of Brownfields Regeneration: International and Inter-Stakeholder Perspective

Directory of Open Access Journals (Sweden)

Bohumil FRANTÁL

2015-02-01

Full Text Available The paper presents the results of an interna-tional comparative survey of stakeholders from four European countries (the Czech Republic, Germany, Poland and Romania. The aim was to identify and classify the ‘success factors’ of brownfelds regeneration and to detect signifcant convergences and divergences concerning the drivers and barriers of regeneration processes in different geographical and institutional contexts. The existence of ecological burden or site con-tamination, overall regeneration costs and clari-fed ownership relations are considered the most important factors of regeneration internationally. Especially in Romania but also in Poland, the fac-tors at national level (legislation, incentives, and foreign direct investments are perceived to be more infuential than in the Czech Republic and Germany, where a stronger emphasis is put on the location factors (whether a brownfeld is lo-cated in rural, urban or inner city area and trans-port links. Physical attributes such as the site’s area and terrain are also considered among the most signifcant factors in Romania. While rep-resentatives of public administration emphasized more the importance of legislation, state incen-tives and general localization, the investors and developers highlighted local factors (landscape protection limits, place marketing, and previous use of brownfelds. The emphasis on political and geographical factors increases with the level of experience of stakeholders, while the empha-sis on site specifc factors decreases with the length of experience.

Germany's socio-economic model and the Euro crisis

Directory of Open Access Journals (Sweden)

Michael Dauderstädt

2013-03-01

Full Text Available Germany's socio-economic model, the "social market economy", was established in West Germany after World War II and extended to the unified Germany in 1990. During a prolonged recession after the adoption of the Euro in 1998, major reforms (Agenda 2010 were introduced which many consider as the key of Germany's recent success. The reforms had mixed results: employment increased but has consisted to a large extent of precarious low-wage jobs. Growth depended on export surpluses based on an internal real devaluation (low unit labour costs which make Germany vulnerable to global recessions as in 2009. Overall inequality increased substantially.

Nudging Germany

DEFF Research Database (Denmark)

Purnhagen, Kai; Reisch, Lucia A.

Since 2015 behavioural scientists investigate at the German chancellery how one could regulate better. This piece illustrates the background of this new strategy and possible concequences for regulation and Rechtswissenschaft in Germany. We first discuss the concept of behaviourally informed regu...

Firmino Costa, un intelectual de la República y sus propósitos educativos (1907-1937

Directory of Open Access Journals (Sweden)

Juliana Cesário Hamdan

2014-01-01

Full Text Available El presente artículo pretende analizar la actu - ación del educador Firmino Costa, nacido en Minas Gerais, al retomar sus antecedentes his - tóricos que se localizan en la base de las formas de su actuación política e intelectual. Para este análisis, recurrimos al trabajo de Alonso (2008, 1 Oliveira (1999 2 y Carvalho (2003, 3 considera - mos las expresivas contribuciones para su com - prensión en relación con la historia e ideas que circularon en este periodo, comprendido entre los años que antecedieron a las primeras déca - das de la Proclamación de la República en Brasil (I889. Las tres obras, pese a que se escribieron a partir de objetos y objetivos distintos, refuta - ron interpretaciones que, por un lado, tratan el escenario intelectual de la República por medio de tipologías de intelectuales, que estarían ab - sorbiendo pasivamente las teorías europeas y norteamericanas. Y, por otro lado, las que son marcadas por estudios que enfatizan las acciones individuales, empeñadas en llevar adelante sus banderas ideológicas. Al contrario, los autores entienden que los sujetos están inmersos en de - terminado entorno cultural, constituido por las redes de sociabilidad y por el repertorio de ideas en circulación y, por eso mismo, tienen formas distintas de actuación política e intelectual. Y ese escenario condiciona, en gran medida, las posi - bilidades de actuación. Así, este artículo busca establecer conexiones entre algunos elementos del escenario cultural, presentes en los años que antecedieron y en los que sucedieron a la República, relacionándolos a las formas de actuación política e intelectual que informan la acción educacional del educador minero. Ese movimiento analítico, por su vez, exigió que recorriésemos a algunas de las formu - laciones teóricas de Antonio Gramsci, en lo que se refiere a los sentidos de actuación de los inte - lectuales, como forma de comprenderlos a partir del contexto y de las

Germany. A pioneer on earthen feet?

International Nuclear Information System (INIS)

Michaelowa, A.

2003-01-01

Germany is one of the two OECD countries having achieved substantial greenhouse gas reductions in the last decade. While a part was large reductions in industry after the economic crash in East Germany, a relevant share is due to the huge public infrastructure investments in East Germany. The real success of German climate policy in the past decade is the strong reduction of methane and nitrous oxide which has been almost unnoticed. German climate policy is a good example of how lobbying of interest groups leads to a complex maze of hundreds of measures whose effects are difficult to evaluate. Paradoxically, policies have focused on expensive measures and Germany clearly is a pioneer in the most expensive forms of renewable energy. Concerning cost-effective measures and market instruments, Germany is a laggard. Only slowly, policymakers start to notice this distortion and first, shaky steps towards a more cost-efficient policy are made. Several challenges such as nuclear phase-out and trends in household energy consumption will put pressure on government to embrace the Kyoto Mechanisms and to refocus domestic instruments well before the first commitment period

Summary Record of the First Meeting of the Radioactive Waste Repository Metadata Management (RepMet) Initiative

International Nuclear Information System (INIS)

2014-01-01

National radioactive waste repository programmes are collecting large amounts of data to support the long-term management of their nations' radioactive wastes. The data and related records increase in number, type and quality as programmes proceed through the successive stages of repository development: pre-siting, siting, characterisation, construction, operation and finally closure. Regulatory and societal approvals are included in this sequence. Some programmes are also documenting past repository projects and facing a challenge in allowing both current and future generations to understand actions carried out in the past. Metadata allows context to be stored with data and information so that it can be located, used, updated and maintained. Metadata helps waste management organisations better utilise their data in carrying out their statutory tasks and can also help verify and demonstrate that their programmes are appropriately driven. The NEA Radioactive Waste Repository Metadata Management (RepMet) initiative aims to bring about a better understanding of the identification and administration of metadata - a key aspect of data management - to support national programmes in managing their radioactive waste repository data, information and records in a way that is both harmonised internationally and suitable for long-term management and use. This is a summary record of the 1. meeting of the RepMet initiative. The actions and decisions from this meeting were sent separately to the group after the meeting, but are also included in this document (Annex A). The list of participants is attached as well (Annex B)

Adeno-associated virus Rep-mediated targeting of integrase-defective retroviral vector DNA circles into human chromosome 19

International Nuclear Information System (INIS)

Huang, Shuohao; Kawabe, Yoshinori; Ito, Akira; Kamihira, Masamichi

2012-01-01

Highlights: ► Adeno-associated virus (AAV) is capable of targeted integration in human cells. ► Integrase-defective retroviral vector (IDRV) enables a circular DNA delivery. ► A targeted integration system of IDRV DNA using the AAV integration mechanism. ► Targeted IDRV integration ameliorates the safety concerns for retroviral vectors. -- Abstract: Retroviral vectors have been employed in clinical trials for gene therapy owing to their relative large packaging capacity, alterable cell tropism, and chromosomal integration for stable transgene expression. However, uncontrollable integrations of transgenes are likely to cause safety issues, such as insertional mutagenesis. A targeted transgene integration system for retroviral vectors, therefore, is a straightforward way to address the insertional mutagenesis issue. Adeno-associated virus (AAV) is the only known virus capable of targeted integration in human cells. In the presence of AAV Rep proteins, plasmids possessing the p5 integration efficiency element (p5IEE) can be integrated into the AAV integration site (AAVS1) in the human genome. In this report, we describe a system that can target the circular DNA derived from non-integrating retroviral vectors to the AAVS1 site by utilizing the Rep/p5IEE integration mechanism. Our results showed that after G418 selection 30% of collected clones had retroviral DNA targeted at the AAVS1 site.

La disputa por la república en el siglo XIX y la prensa en México

OpenAIRE

Toussaint, Florence

2006-01-01

A partir de la consumación de la independencia, se inicia la disputa por definir el tipo de gobierno que había de asumir el país. Esta oscila entre la República federal y la centralista durante casi todo el tiempo, aunque hay dos momentos en los cuales la forma monárquica aparece como opción. Se conoce a estos periodos como el Primer Imperio y el Segundo Imperio. No duran muchos años. Sin embargo, dan lugar a enconadas luchas internas, sobre todo durante la presencia de...

Política externa do vizinho distante : estudo de caso da República Cooperativa da Guiana

OpenAIRE

Lima, Erick Cavalcanti Linhares

2012-01-01

Esta tese trata das relações externas da República Cooperativa da Guiana, num recorte temporal de quarenta e quatro anos, que vão desde a independência, em 1966 até 2010, período no qual se desenvolveram importantes transformações mundiais, bem como no relacionamento político-diplomático. Remontam a essa época, a formação do marco institucional de representação dos interesses sociais e produtivos, tanto na economia guianense, quanto no âmbito internacional. O objetivo foi traç...

76 FR 10500 - Nationally Recognized Testing Laboratories Fees

Science.gov (United States)

2011-02-25

....'' Nat'l Cable Television Ass'n v. U.S., 415 U.S. 336 (1974), quoting H.R. Rep. No. 82-384, at 2-3 (1951... Court decided the companion cases of Nat'l Cable Television Ass'n, 415 U.S. 336, and Fed. Power Comm'n v... companies. Fed. Power Comm'n, 415 U.S. at 349. In Nat'l Cable Television Ass'n, Inc. v. FCC, 554 F.2d 1094...

Integrated solid waste management in Germany

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-07-01

This report covers Germany`s experience with integrated solid waste management programs. The municipal solid waste practices of four cities include practices and procedures that waste facility managers with local or state governments may consider for managing their own day-to-day operations.

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African Journals Online (AJOL)

PUBLICATIONS1

The root extract was more effective in controlling both insects, and it was ... food for more than 1.2 billion people in sub-. Saharan Africa and ... beverages and the leaves are fed to animals. MATERIALS AND ..... Marketing Res. Rep. no. 882 ...

Germany after Federal elections

International Nuclear Information System (INIS)

Niedzballa, G.

2010-01-01

The political, economical and social situation in Germany after the election and attitude to nuclear energy are summarised. The Coalition agreement include: 1.Extension of the remaining lifetimes of the nuclear power plants (Nuclear Power considered as “Bridging technology”; Safety first; Skimming of additional profits) 2. No nuclear new builds in Germany 3. Approval and promotion (loan guarantees) of nuclear exports 4. Reversal of the moratorium regarding the exploration of Gorleben salt dome (Completion of the exploration; International Peer Review Group) 5.Further research regarding competence preservation and safety

[Tularemia in Germany].

Science.gov (United States)

Kohlmann, R; Geis, G; Gatermann, S G

2014-07-01

The bacterium Francisella tularensis is known for more than 100 years by now as the etiological agent of the disease tularemia, a zoonotic infection with a worldwide distribution in the Northern Hemisphere. The prevalence of tularemia shows a wide geographic variation, being comparably infrequent in Germany. Tularemia can present itself with multiple clinical manifestations including ulceroglandular, glandular, oropharyngeal, oculoglandular, respiratory and typhoidal forms. Due to the low prevalence and the unspecific symptomatology, a rapid diagnosis and early start of an effective therapy are rarely obtained. Thus, in this article we summarize important aspects concerning etiology, ecology and routes of transmission, recent epidemiologic situation, clinical picture, diagnostics and treatment of tularemia, focusing on the situation in Germany. © Georg Thieme Verlag KG Stuttgart · New York.

Recent facts about photovoltaics in Germany

International Nuclear Information System (INIS)

Wirth, Harry

2015-01-01

Germany is leaving the age of fossil fuel behind. In building a sustainable energy future, photovoltaics is going to have an important role. The following summary consists of the most recent facts, figures and findings and shall assist in forming an overall assessment of the photovoltaic expansion in Germany.

Transport of radioactive waste in Germany - a survey

International Nuclear Information System (INIS)

Alter, U.

1995-01-01

The transport of radioactive waste is centralised and coordinated by the German Railway Company (Deutsche Bahn AG, DB) in Germany. The conditioning of radioactive waste is now centralised and carried out by the Gesellschaft fuer Nucklear Service (GNS). The Germany Railway Company, DB, is totally and exclusively responsible for the transport, the GNS is totally and exclusively responsible for the conditioning of radioactive waste. The German Railway Company transports all radioactive waste from nuclear power plants, conditioning facilities and the existing intermediate storage facilities in Germany. In 1992 nearly 177 shipments of radioactive waste were carried out, in 1991 the total amount was 179 shipments. A brief description of the transport procedures, the use of different waste packages for radioactive waste with negligible heat generation and the transport routes within Germany will be given. For this purpose the inspection authorities in Germany have used a new documentation system, a special computer program for waste flow tracking and quality assurance and compliance assurance, developed by the electrical power companies in Germany. (Author)

Maquiavel Versus Rousseau: as Divisões Sociais e Seu Papel em uma República Bem-Ordenada

Directory of Open Access Journals (Sweden)

Renato Moscateli

2015-01-01

Full Text Available RESUMO:As relações de conflito entre os grupos sociais constituem um tópico relevante para a filosofia política, e as maneiras distintas como elas são interpretadas dependem de uma visão mais ampla sobre as condições apropriadas a um Estado bem-ordenado. Maquiavel, por exemplo, ao refletir sobre o caso da Roma Antiga, procurou refutar aqueles que condenavam os tumultos entre os nobres e a plebe da cidade, como se eles tivessem provocado apenas males à república. Para o autor, tais tumultos estavam entre as principais causas da liberdade romana, visto que a diferença nos “humores” dos grandes e do povo resultou em embates que deram origem às leis favoráveis à liberdade. Rousseau, por sua vez, descreveu a existência de “associações particulares” dentro da sociedade civil como algo potencialmente nocivo à harmonia da república, pois cada uma delas contém um interesse particular passível de se sobrepor ao bem comum, nas deliberações públicas, prejudicando o prevalecimento da vontade geral. Ainda para o genebrino, a ocorrência de longos debates e de tumultos nas assembleias populares poderia ser um sinal de divisões internas capazes de ocasionar a ruína do Estado. Frente a essas duas maneiras de conceber o papel político dos conflitos sociais, o objetivo deste trabalho é realizar uma análise comparativa das ideias de Maquiavel e de Rousseau.

Las enseñanzas de sordomudos durante la II República Española. Una perspectiva histórica

Directory of Open Access Journals (Sweden)

Alfredo ALCINA MADUEÑO

2011-07-01

Full Text Available Las enseñanzas de sordomudos en el periodo de la II República española es un tema poco estudiado e inédito en determinados aspectos. Se puede decir que participa de las características de la educación general de dicha etapa: esfuerzo económico y presupuestario de los gobiernos, renovación metodológica, modernización del sistema, ampliación de la red escolar, formación del magisterio, etc., si bien presenta una idiosincrasia muy marcada e incluso contradictoria, no solo por la conocida contraposición de los gobiernos de un bienio y otro (31/33 y 34/35, sino también por las decisiones de política educativa que se toman por los mismos gobiernos de la coalición republicano-socialista. El legado de la aportación republicana es más documental que de realizaciones concretas, y tendrá mayor aplicación en el régimen político que aniquila y sucede a la República que en ella misma. La consideración de fuentes primarias (legales y documentales fundamentan principalmente las conclusiones de esta exposición.

El poder local en la provincia de Albacete durante la II República y el intervencionismo del gobierno, 1931-1936

Directory of Open Access Journals (Sweden)

Manuel REQUENA

2016-05-01

Full Text Available Este artículo estudia los diversos procesos electorales de carácter municipal durante la II República en la provincia de Albacete, las constantes interferencias del Gobierno de turno sustituyendo los consistorios democráticamente elegidos por gubernamentales, la lucha por el control del poder local y las medidas adoptadas para resolver los problemas locales y la conflictividad generada.

Eastern Germany Ahead in Employment of Women

OpenAIRE

Elke Holst; Anna Wieber

2014-01-01

Almost a quarter of a century after the fall of the Wall, there are still more women in employment in eastern Germany than in the west. Although the disparity is marginal now, the two regions started from dramatically different levels. In 1991, immediately after reunification, the employment rate for women in western Germany was 54.6 percent, but since then it has increased year on year, reaching 67.5 percent in 2012. In eastern Germany, female employment initially plummeted after the fall of...

Depression Disturbs Germany

Institute of Scientific and Technical Information of China (English)

2011-01-01

The suicide of Robert Enke,the goalkeeper of the Germany national football team who had battled depression for years,stunned the country and cast depression into the national spotlight as a disturbing disease.

Alejandro Bunge y el problema de la vivienda obrera en la República Argentina (1910-1915

Directory of Open Access Journals (Sweden)

Jorge A. Núñez

2010-02-01

Full Text Available Este trabajo pretende indagar, a partir del estudio de la figura del economista Alejandro Bunge, en la problemática de la vivienda obrera en la República Argentina en las primeras décadas de la pasada centuria. Aquí se argumentará que los estudios realizados porAlejandro Bunge como director de la División Estadísticas del Departamento Nacional de Trabajo en el período 1910-1915 contribuyeron de manera notable a la elaboración del proyectoy posterior sanción de la Ley de Casas Baratas para Obreros (n°9677.

La República peregrina: hombres de armas y letras en América Andina, 1810-1884

OpenAIRE

Thibaud, Clément

2014-01-01

Del 18 al 20 de mayo de 2005 se realizó en el Instituto de Estudios Peruanos el coloquio internacional «La República peregrina: Hombres de armas y letras en América Andina, 1810-1884». El evento, co-organizado por el Instituto Francés de Estudios Andinos y el IEP, reunió durante tres días a una veintena de historiadores especialistas en el siglo XIX, provenientes de todos los países andinos —de Chile hasta Venezuela, pasando por Argentina—, pero también de Inglaterra, Francia y Estados Unidos...

A Grande Guerra e as relações internacionais de Portugal: Da Monarquia à República

OpenAIRE

Castaño, David

2014-01-01

Neste artigo procuramos recuperar algumas das ideias que ajudam a explicar a participação portuguesa na Grande Guerra e a opção do Partido Democrático pelo envolvimento do País na frente europeia. Um pleno entendimento da participação portuguesa na Grande Guerra exige não apenas um recuo temporal, mas uma visão abrangente entre dinâmicas internas e externas. Nas primeiras, importa ter em consideração o binómio monarquia/república, e também as profundas divergências que rapidamente dividiram o...

Contrasting evolution patterns between glacier-fed and non-glacier-fed lakes in the central Tibetan Plateau and driving force analysis

Science.gov (United States)

Song, C.; Sheng, Y.

2015-12-01

High-altitude lakes in the Tibetan Plateau (TP) showed strong spatio-temporal variability during past decades. The lake dynamics can be associated with several key factors including lake type, supply of glacial meltwater, local climate variations. It is important to differentiate these factors when analyzing the driving force of lakes dynamics. With a focus on lakes over the Tanggula Mountains of the central TP, this study investigates the temporal evolution patterns of lake area and water level of different types: glacier-fed closed lake, non-glacier-fed closed lake and upstream lake (draining into closed lakes). We collected all available Landsat archive data and quantified the inter-annual variability of lake extents. Results show accelerated expansions of both glacier-fed and non-glacier-fed lakes during 1970s-2013, and different temporal patterns of the two types of lakes: the non-glacier-fed lakes displayed a batch-wise growth pattern, with obvious growth in 2002, 2005 and 2011 and slight changes in other years, while glacier-fed lakes showed steady expanding tendency. The contrasting patterns are confirmed by the distinction of lake level change between the two groups derived from satellite altimetry during 2003-2009. The upstream lakes remained largely stable due to natural drainage regulation. The intermittent expansions for non-glacier-fed lakes were found to be related to excessive precipitation events and positive "precipitation-evaporation". In contrast, glacier-fed lake changes showed weak correlations with precipitation variations, which imply a joint contribution from glacial meltwater to water budgets. A simple estimation reveals that the increased water storage for all of examined lakes contributed from precipitation/evaporation (0.31±0.09 Gt/yr) slightly overweighed the glacial meltwater supply (0.26±0.08 Gt/yr).

Organochlorine compounds in breast-fed vs. bottle-fed infants: preliminary results at six weeks of age

Energy Technology Data Exchange (ETDEWEB)

Lackmann, G.-M.; Schaller, K.-H.; Angerer, J

2004-08-15

Background: Polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) are ubiquitous compounds with carcinogenic and teratogenic properties. They are chemically very stable and lipophilic and, therefore, accumulate in our food-chain. They are prenatally transmitted from mother to foetus, and mother's milk due to its high lipid content is an elimination pathway of special importance. Therefore, breast-feeding has been held responsible for elevated concentrations of these organochlorine compounds as well as for harmful effects in children later in life. Methods: Blood samples (2.5 ml) were taken from each 10 breast-fed and bottle-fed infants at 6 weeks of age. Blood specimens were immediately centrifuged, and serum was stored in glass tubes at -20 degree sign C until analysis. Three higher chlorinated PCB congeners (IUPAC nos. 138, 153 and 180), HCB, and the organic metabolite of DDT, p,p<<-DDE, were analysed with capillary gas chromatography with electron capture detection. Reliability was tested with gas chromatography-mass spectrometry. Results: There were no differences between the study groups of breast-fed and bottle-fed infants with regard to sex distribution, gestational age, birth-weight, age of the mothers, and smoking behaviour of the parents. In contrast, serum concentrations of all organochlorine compounds were significantly higher (P<0.0001) in breast-fed than in bottle-fed infants (mean): PCB 138, 0.38 vs. 0.10 {mu}g/l; PCB 153, 0.49 vs. 0.1 {mu}g/l; PCB 180, 0.31 vs. 0.04 {mu}g/l; {sigma}PCB, 1.19 vs. 0.29 {mu}g/l; HCB, 0.13 vs. 0.04 {mu}g/l; p,p<<-DDE, 1.05 vs. 0.18 {mu}g/l. Conclusions: Breast-feeding significantly increases the pollution of our infants with different organochlorine compounds as early as at 6 weeks of age. The progress of the present study will show whether this pollution will further increase with longer duration of breast-feeding, and whether breast-feeding bears any

Organochlorine compounds in breast-fed vs. bottle-fed infants: preliminary results at six weeks of age

International Nuclear Information System (INIS)

Lackmann, G.-M.; Schaller, K.-H.; Angerer, J.

2004-01-01

Background: Polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) are ubiquitous compounds with carcinogenic and teratogenic properties. They are chemically very stable and lipophilic and, therefore, accumulate in our food-chain. They are prenatally transmitted from mother to foetus, and mother's milk due to its high lipid content is an elimination pathway of special importance. Therefore, breast-feeding has been held responsible for elevated concentrations of these organochlorine compounds as well as for harmful effects in children later in life. Methods: Blood samples (2.5 ml) were taken from each 10 breast-fed and bottle-fed infants at 6 weeks of age. Blood specimens were immediately centrifuged, and serum was stored in glass tubes at -20 degree sign C until analysis. Three higher chlorinated PCB congeners (IUPAC nos. 138, 153 and 180), HCB, and the organic metabolite of DDT, p,p<<-DDE, were analysed with capillary gas chromatography with electron capture detection. Reliability was tested with gas chromatography-mass spectrometry. Results: There were no differences between the study groups of breast-fed and bottle-fed infants with regard to sex distribution, gestational age, birth-weight, age of the mothers, and smoking behaviour of the parents. In contrast, serum concentrations of all organochlorine compounds were significantly higher (P<0.0001) in breast-fed than in bottle-fed infants (mean): PCB 138, 0.38 vs. 0.10 μg/l; PCB 153, 0.49 vs. 0.1 μg/l; PCB 180, 0.31 vs. 0.04 μg/l; ΣPCB, 1.19 vs. 0.29 μg/l; HCB, 0.13 vs. 0.04 μg/l; p,p<<-DDE, 1.05 vs. 0.18 μg/l. Conclusions: Breast-feeding significantly increases the pollution of our infants with different organochlorine compounds as early as at 6 weeks of age. The progress of the present study will show whether this pollution will further increase with longer duration of breast-feeding, and whether breast-feeding bears any health risks for our

Mapa educativo nacional. Una experiencia en la República Argentina

Directory of Open Access Journals (Sweden)

Horacio Rodolfo Bozzano

2006-01-01

Full Text Available El Proyecto Mapa Educativo Nacional (MEN es un SIG generado a partir del desarrollo e integración de 24 Mapas Educativos Provinciales sobre la base de un modelo conceptual general, con una visión dinámica de los 49.000 establecimientos educativos, así como de su contexto territorial. Los objetivos del trabajo son: a sistematizar los aportes al Proyecto MEN desde la teoría cartográfica, reconociendo instancias de concepción, construcción y comunicación de los mapas que lo integran, así como vinculaciones entre territorio, espacio y espacialidades emergentes de la concreción de la tarea; y b identificar en qué medida la concreción del Proyecto MEN en la República Argentina contribuye a fortalecer un enfoque dialéctico conocimiento-realidad sobre el territorio y la gestión aplicado a un objeto de estudio e intervención concreto de desarrollo institucional, con el propósito de promover un círculo virtuoso de transformación entre sujetos de cambio y agentes de desarrollo.

The visual arts influence in Nazi Germany

Directory of Open Access Journals (Sweden)

Bie Yanan

2016-01-01

Full Text Available This article will discuss the influence of visual art in Nazi Germany from two parts of visual arts, which are political photography and poster propaganda, analyzing the unique social and historical stage of Nazi Germany. And it emphasizes the ideology of the Nazis, which in Nazi Germany inflamed the political sentiment of the masses and took the visual art as their important instrument of political propaganda, while Nazi party used visual art on anti-society and war which is worth warning and criticizing for later generation.

Market value-oriented gas pricing in Germany

International Nuclear Information System (INIS)

Eimermacher, T.

1996-01-01

In Germany, natural gas faces stiff competition from other types of energy. In many applications, natural gas is capable of replacing other fuels. In addition there is a growing gas-to-gas competition in some European countries, either through pipeline construction by a competitor as in Germany or by mandatory third-party access as in UK. Competition leads to market value-oriented energy pricing, which is particularly evident in Germany. For the consumer, this competitive situation ensures that natural gas can be obtained (and remains available in the long term) at competitive prices

Agro-environmental policies in Germany

International Nuclear Information System (INIS)

Frohberg, K.; Weingarten

1997-01-01

Agricultural activities always have impacts on the environment. Whereas soil erosion is a minor problem in Germany water pollution due to modern and intensive agriculture is of major concern. At first the paper discusses to what extent agriculture contributes to environmental pollution in Germany, in particular to the pollution of surface waters (as well as hydroelectric power constructions on the Danube) and groundwater by nutrients and pesticides. Agro-environmental policy in Germany is dominated by command-and-control-measures. Hence, in the second section, recent developments of the most important legal and institutional settings concerning water conservation policies are surveyed with special emphasis on the Federal Water Act and the Implementation of the Nitrate Directive into German legislation by the Fertilizer Ordinance. Thirdly, impacts of alternative water conservation policies are investigated using a regionalized agricultural sector model. Information obtained by this model analysis cover the development of N-balances, potential nitrate concentrations in the recharged groundwater, costs potentially effected by this and resulting agricultural incomes on the country level of the former Federal Republic Germany. The last section focuses on programs promoting environmentally sound farming practices, which gained increasing importance in the Common Agricultural Policy of the European Union in the last years. It is argued that this development will also continue in the future. (author)

EMI in Germany

DEFF Research Database (Denmark)

Weiss, Felix; Schindler, Steffen

2017-01-01

This article discusses effectively maintained inequality considering two different examples from the Germany education system: secondary school attainment and enrolment in highly ranked universities among freshmen. In our analyses of secondary school attainment, we investigate whether considering...

Hombres de letras en la provincia. Producción y comercio de libros en la República de Colombia, 1821-1874

Directory of Open Access Journals (Sweden)

Rafael E. Acevedo P.

2016-01-01

Full Text Available Han sido pocos los estudios en la historiografía nacional sobre el proceso de producción y comercialización de libros en la República de Colombia durante el siglo xix. A partir del análisis de las actividades de los impresores, los escritores de textos, los comerciantes y las autoridades políticas en Cartagena, en este artículo se demostrará que la difusión de las letras en la sociedad republicana estuvo sujeta a la dinámica de impresión y comercialización de obras de educación impulsada por los hombres de letras desde las provincias. Esta dinámica se constituyó en la base inicial de la formación de un pequeño mercado editorial en la República y fue posible gracias a los usos de la libertad de imprenta, las demandas de la alfabetización y las negociaciones de los autores con los gobiernos locales y nacionales. Se busca así contribuir al análisis de un problema sobre el que existen escasos trabajos en el contexto regional colombiano.

Germany at CERN

CERN Multimedia

2005-01-01

From left to right: Maximilian Metzger, CERN's Secretary-General, Hermann Schunck, Director at the German Federal Ministry of Education and Research, and Robert Aymar, CERN's Director-General, talking to Wolfgang Holler from Butting, one of the companies at the "Germany at CERN" exhibition. Far right : Susanne-Corinna Langer-Greipl from BMBF, delegate to the CERN Finance Committee. For three days, CERN's Main Building was transformed into a showcase for German industry. Twenty-nine companies from sectors related to particle physics (electrical engineering, vacuum and low temperature technology, radiation protection, etc.) were here for the ninth "Germany at CERN" exhibition, organised by the German Federal Ministry of Education and Research (BMBF), which gave them the opportunity to meet scientists and administrators from the Laboratory. On 1 March the exhibition was visited by a German delegation headed by Dr Hermann Schunck, Director at BMBF.

Testicular damage in rats fed on irradiated diets

International Nuclear Information System (INIS)

Kushwaha, A.K.S.; Hasan, S.S.

1986-01-01

Feeding effect of irradiated diets was studied on the pups born to mother fed either on irradiated normal diet or irradiated low protein diet. The study indicated that pups born to mother fed on the irradiated low protein diet had fewer spermatogonial cells in the testes than those given irradiated normal diet and unirradiated low protein diet. Similarly, pups maintained on the irradiated low protein diet showed marked decrease in alkaline phosphatase and cholesterol contents in the testes rather than in the pups fed irradiated normal as well as unirradiated low protein diets. The irradiated low protein diet fed pups showed increased depletion and vacuolization of adrenocortical and medullary cells. 13 refs., 15 figures. (author)

Testicular damage in rats fed on irradiated diets

Energy Technology Data Exchange (ETDEWEB)

Kushwaha, A K.S.; Hasan, S S

1986-12-01

Feeding effect of irradiated diets was studied on the pups born to mother fed either on irradiated normal diet or irradiated low protein diet. The study indicated that pups born to mother fed on the irradiated low protein diet had fewer spermatogonial cells in the testes than those given irradiated normal diet and unirradiated low protein diet. Similarly, pups maintained on the irradiated low protein diet showed marked decrease in alkaline phosphatase and cholesterol contents in the testes rather than in the pups fed irradiated normal as well as unirradiated low protein diets. The irradiated low protein diet fed pups showed increased depletion and vacuolization of adrenocortical and medullary cells. 13 refs., 15 figures.

João do Rio, Repórter da Pobreza na Cidade

Directory of Open Access Journals (Sweden)

Denise da Costa Oliveira Siqueira

2004-06-01

Full Text Available Tendo como modelo a Belle Époque parisiense, o Rio de Janeiro, na virada do século XIX para o XX, sofria a transição para uma ordem capitalista urbana. Nesse contexto, o escritor e repórter João Paulo Barreto - o João do Rio - vagou pela cidade, observou parcelas da sociedade que raramente figuravam nas páginas de livros e jornais. No livro A Alma Encantadora das Ruas dedicou um capítulo às várias formas de pobreza e exploração presentes na capital federal. A partir dessa temática, o objetivo deste artigo é estudar as representações da pobreza como apresentadas no livro de João do Rio e paralelamente abordar a questão do texto jornalístico como mediador simbólico - reflexo de um tempo e de uma cultura.

Vapor-fed bio-hybrid fuel cell.

Science.gov (United States)

Benyamin, Marcus S; Jahnke, Justin P; Mackie, David M

2017-01-01

Concentration and purification of ethanol and other biofuels from fermentations are energy-intensive processes, with amplified costs at smaller scales. To circumvent the need for these processes, and to potentially reduce transportation costs as well, we have previously investigated bio-hybrid fuel cells (FCs), in which a fermentation and FC are closely coupled. However, long-term operation requires strictly preventing the fermentation and FC from harming each other. We introduce here the concept of the vapor-fed bio-hybrid FC as a means of continuously extracting power from ongoing fermentations at ambient conditions. By bubbling a carrier gas (N 2 ) through a yeast fermentation and then through a direct ethanol FC, we protect the FC anode from the catalyst poisons in the fermentation (which are non-volatile), and also protect the yeast from harmful FC products (notably acetic acid) and from build-up of ethanol. Since vapor-fed direct ethanol FCs at ambient conditions have never been systematically characterized (in contrast to vapor-fed direct methanol FCs), we first assess the effects on output power and conversion efficiency of ethanol concentration, vapor flow rate, and FC voltage. The results fit a continuous stirred-tank reactor model. Over a wide range of ethanol partial pressures (2-8 mmHg), power densities are comparable to those for liquid-fed direct ethanol FCs at the same temperature, with power densities >2 mW/cm 2 obtained. We then demonstrate the continuous operation of a vapor-fed bio-hybrid FC with fermentation for 5 months, with no indication of performance degradation due to poisoning (of either the FC or the fermentation). It is further shown that the system is stable, recovering quickly from disturbances or from interruptions in maintenance. The vapor-fed bio-hybrid FC enables extraction of power from dilute bio-ethanol streams without costly concentration and purification steps. The concept should be scalable to both large and small

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African Journals Online (AJOL)

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Potestades Administrativas para Denegar Solicitudes de Derechos de Aguas Subterráneas y Retroactividad: Dictamen N° 5.215, de la Contraloría General de la República, de 31 de enero de 2006

OpenAIRE

Vergara Blanco, Alejandro

2007-01-01

Comenta favorablemente el autor un dictamen de la Contraloría General de la República relativo al otorgamiento de derechos de aprovechamiento de aguas por la Dirección General de Aguas, en el cual se precisan las causales de denegación de su concesión y asimismo se aclara la limitada retroactividad de la reciente Ley Nº 20.017, de 2005, modificatoria del Código de Aguas. The autor comments favourably upon a decision from the Contraloría General de la República (the Chilean Authority whose ...

Un ministro para la Defensa de la República desde el exilio : Juan Hernández Saravia

Directory of Open Access Journals (Sweden)

Manuela Aroca Mohedano

2004-01-01

Full Text Available La nueva situación internacionai surgida tras el final de la II Guerra Mundial propició la recuperación de las instituciones republicanas españolas en el exilio. Juan Hernández Saravia, un militar profesional, azañista y republicano, será el ministro de la Defensa Nacional de la República Española. Entre posibilidades reales y utopías, a caballo entre la defensa a ultranza de la legalidad y la protección de los movimientos clandestinos antifranquistas, en medio de las disensiones de los militares exiliados dispersos en varios continentes, discurrirá la actuación de un Ministerio que tendrá como objetivo principal la recuperación del ejército para la futura restaurada República y que verá truncadas sus expectativas por la aparición en el panorama mundial de los primeros.A Minister in exile for tfie Republic Defence: Juan Hernández Saravia The new International situation arisen after the end of the Second World War led to the recovery of Spanish Republic Institutions in exile. Juan Hernández Saravia, an army officer, republican and adherent to Azaña, became the National Defence Minister of Spanish Republic. Among real possibilities and utopia, halfway between a vigorous legality defence and the protection of clandestino movements against Franco's dictatorship, the main objective of this Ministery was the army recovery for the futuro restoring Republic, but the early Cold War shattered these prospects.

Is Germany a model for managers?

Science.gov (United States)

Wever, K S; Allen, C S

1992-01-01

Most American managers have a hard time making sense of Germany. The country has a fraction of the resources and less than one-third the population of the United States. Labor costs are substantially higher, paid vacations are at least three times as long, and strong unions are deeply involved at all levels of business, from the local plant to the corporate boardroom. Yet German companies manage to produce internationally competitive products in key manufacturing sectors, making Germany the greatest competitive threat to the United States after Japan. The seemingly paradoxical nature of the German economy typically evokes one of two diametrically opposed responses. The first is to celebrate the German economy as a "model" worth emulating--indeed, as the answer to declining U.S. competitiveness. The alternative, more skeptical response is to question Germany's staying power in a new, more competitive global economy. According to Kirsten Wever and Christopher Allen, the problem with both points of view is that they miss the forest for the trees. Observers are so preoccupied with praising--or blaming--individual components of the German economy that they fail to see the dynamic logic that ties these components together into a coherent system. In their review of recent research on the German business system, Wever and Allen argue that managers can learn an important lesson from Germany. In the global economy, competition isn't just between companies but between entire socioeconomic systems. Germany's ability to design a cohesive economic and social system that adapts continuously to changing requirements goes a long way toward explaining that country's competitive success.

GERMANY & TURKEY – A PARTNERSHIP PERSPECTIVE

Directory of Open Access Journals (Sweden)

Bestenigar KARA

2015-04-01

Full Text Available The article shortly deals with economic and commercial relations between Turkey, that keeps close regulary economic, political and cultural relationship and Germany, which is one of six founding fathers of the European Union. The subject of article has been searched within the following framework: Measurement of commercial relations between export and import between, investment relations between Germany and Turkey, mutual distribution sector.

FED, Geometry Input Generator for Program TRUMP

International Nuclear Information System (INIS)

Schauer, D.A.; Elrod, D.C.

1996-01-01

1 - Description of program or function: FED reduces the effort required to obtain the necessary geometric input for problems which are to be solved using the heat-transfer code, TRUMP (NESC 771). TRUMP calculates transient and steady-state temperature distributions in multidimensional systems. FED can properly zone any body of revolution in one, or three dimensions. 2 - Method of solution: The region of interest must first be divided into areas which may consist of a common material. The boundaries of these areas are the required FED input. Each area is subdivided into volume nodes, and the geometrical properties are calculated. Finally, FED connects the adjacent nodes to one another, using the proper surface area, interface distance, and, if specified, radiation form factor and interface conductance. 3 - Restrictions on the complexity of the problem: Rectangular bodies can only be approximated by using a very large radius of revolution compared to the total radial thickness and by considering only a small angular segment in the circumferential direction

Mental health of Turkish women in Germany

DEFF Research Database (Denmark)

Bromand, Z; Temur-Erman, S; Yesil, R

2012-01-01

The purpose of the present study was to examine the protective and risk factors of mental distress among Turkish women living in Germany.......The purpose of the present study was to examine the protective and risk factors of mental distress among Turkish women living in Germany....

Poverty, health, and nutrition in Germany.

Science.gov (United States)

Helmert, U; Mielck, A; Shea, S

1997-01-01

To investigate the relation between poverty and several variables describing health and nutrition behavior in East Germany and West Germany. Data are from the third National Health Survey in West Germany and the first Health Survey for the new federal states of Germany (1991/92). Both health surveys included a self-administered questionnaire ascertaining sociodemographic variables, smoking history, nutritional behavior (using a food-frequency list), physical activity, and a medical examination comprising measurements of height, weight, blood pressure, and blood sampling for serum cholesterol determination. Participants included 4958 subjects in the West Survey and 2186 subjects in the East Survey aged 25-69 years, with a respective net response rate of 69.0% and 70.2%. Poverty was defined as a household equivalence income of 62.5% or less of the median income of the general population. The lowest income group (poverty or near poverty) comprised 11.6% of East German versus 15.9% of West German males and 14.8% of East German versus 19.3% of West German females. For most but not all health and nutrition parameters, less favorable results were obtained for subjects with an equivalence income below or near poverty. The most striking poverty-related differences regarding cardiovascular disease risk factors were found for lack of regular exercise for both genders and obesity in females. No poverty-related differences were found for the prevalence of hypercholesterolemia, despite a much higher prevalence of obesity in persons with an income below the poverty line. Current nutritional behavior and changes in nutritional behavior during the last three years was strongly related to income status, with a more unhealthy status for low-income population groups in both East and West Germany. In Germany, poverty has strong effects on individual health status and nutritional behavior. Because of rising unemployment rates and reductions in social security payments for low

Library Consortia in Germany

Directory of Open Access Journals (Sweden)

Werner Reinhardt

2001-07-01

Full Text Available Looking at the present situation in Germany consortia show a considerable variety of organizational forms. Only in the case of the Friedrich-Althoff-Consortium in Berlin-Brandenburg a corporate body with deed of partnership does exist. In other German states consortia have been formed which are represented by an individual library (e.g. Baden-Württemberg or by a central institution such as the Bayerische Staatsbibliothek in Bavaria or the Hochschulbibliothekszentrum NRW in North Rhine-Westphalia. Rarely contracts for nationwide consortia have been signed; resulting from an initiative of a professional society, the „Gesellschaft Deutscher Chemiker“, an agreement was reached allowing for the use of the Beilstein-Crossfire-database in participating universities all over Germany.

Provisions for containment venting in Germany

International Nuclear Information System (INIS)

Wilhelm, J.G.

1997-01-01

In this short paper an overlook is given of the systems developed in Germany for filtered containment venting and their implementation in nuclear power plants. More information on the development can be found in the Proceedings of the DOE/NRC Aircleaning Conferences. In Germany, 28.8 % of the electric energy is produced by 19 nuclear power reactors. No new power reactor is expected to be built at least within the next ten years, but France and Germany cooperate in the development of a future European Power Reactor (ERP). This reactor type will be fitted with a core catcher and passive cooling in order to avoid serious consequences of a hypothetical core meltdown accident so that provisions for containment venting are not required. 3 refs., 6 figs., 1 tab

Provisions for containment venting in Germany

Energy Technology Data Exchange (ETDEWEB)

Wilhelm, J.G.

1997-08-01

In this short paper an overlook is given of the systems developed in Germany for filtered containment venting and their implementation in nuclear power plants. More information on the development can be found in the Proceedings of the DOE/NRC Aircleaning Conferences. In Germany, 28.8 % of the electric energy is produced by 19 nuclear power reactors. No new power reactor is expected to be built at least within the next ten years, but France and Germany cooperate in the development of a future European Power Reactor (ERP). This reactor type will be fitted with a core catcher and passive cooling in order to avoid serious consequences of a hypothetical core meltdown accident so that provisions for containment venting are not required. 3 refs., 6 figs., 1 tab.

U.S. Rep. Dave Weldon outside the U.S. Lab Destiny in the SSPF.

Science.gov (United States)

1999-01-01

In the Space Station Processing Facility, U.S. Rep Dave Weldon (at left) looks at the U.S. Lab, called Destiny. With him are Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office, Dana Gartzke, the congressman's chief of staffm and Boeing workers. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

Influencia del campo magnético sobre el crecimiento de microorganismos patógenos ambientales aislados en el Archivo Nacional de la República de Cuba

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Matilde Anaya

2015-09-01

Conclusión. Se concluyó que el campo magnético aplicado tuvo un efecto estimulante sobre los microorganismos estudiados, lo cual potencia el riesgo para la salud del personal y los visitantes del Archivo Nacional de la República de Cuba.

Radioactive waste interim storage in Germany

International Nuclear Information System (INIS)

2015-12-01

The short summary on the radioactive waste interim storage in Germany covers the following issues: importance of interim storage in the frame of radioactive waste management, responsibilities and regulations, waste forms, storage containers, transport of vitrified high-level radioactive wastes from the reprocessing plants, central interim storage facilities (Gorleben, Ahaus, Nord/Lubmin), local interim storage facilities at nuclear power plant sites, federal state collecting facilities, safety, radiation exposure in Germany.

Electricity prices differences between France and Germany

International Nuclear Information System (INIS)

Hensing, I.; Nolden, A.; Riechmann, Ch.; Schulz, W.

1998-01-01

High electricity prices in Germany especially as compared to France have played an important role in the electricity liberalization debate in Germany. The price differences can largely be explained by cost differences in electricity generation, the electricity grids, personnel cost and local taxes. Further analysis suggests that efficiency improvements upon market liberalization will only partly remove these price and cost differentials. Parts of the cost differentials are attributable to politically-motivated regulations and the (future) regulation of network functions. This implies that Germany can only expect to arrive at internationally comparable electricity prices if it advances with a reform of political and monopoly regulations alongside liberalizing electricity generation and trade. (author)

Microcirculatory effects of zinc on fructose-fed hamsters.

Science.gov (United States)

Castiglione, R C; Barros, C M M R; Boa, B C S; Bouskela, E

2016-04-01

Fructose is a major dietary component directly related to vascular dysfunction and diseases such as obesity, diabetes, and hypertension. Zinc is considered a non-pharmacological alternative for treating diabetes due to its antioxidant and hyperglycemia-lowering effects in diabetic animals. Therefore, the aim of this study was to evaluate the effects of dietary zinc supplementation on the microcirculatory parameters of fructose-fed hamsters. Male hamsters (Mesocricetus auratus) were fed drinking water substituted by 10% fructose solution for 60 days, whereas control animals were fed drinking water alone. Their microcirculatory function was evaluated using cheek pouch preparation, as well as their blood glucose and serum insulin levels. Their microcirculatory responses to acetylcholine (ACh, an endothelium-dependent vasodilator) and to sodium nitroprusside (SNP, an endothelium-independent vasodilator) as well as the increase in macromolecular permeability induced by 30 min of ischemia/reperfusion (I/R) were noted. Endothelium-dependent vasodilation was significantly increased in control animals with high zinc supplementation compared to the groups without zinc supplementation. Zinc was able to protect against plasma leakage induced by I/R in all control and fructose-fed groups, although the microvascular permeability was higher in animals fed drinking water substituted by 10% fructose solution compared to those fed filtered drinking water alone. Our results indicate that dietary zinc supplementation can improve microvascular dysfunction by increasing endothelial-dependent dilatation and reducing the increase in macromolecular permeability induced by I/R in fructose-fed animals. Copyright © 2015 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

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FED pumped limiter configuration issues

International Nuclear Information System (INIS)

Haines, J.R.; Fuller, G.M.

1983-01-01

Impurity control in the Fusion Engineering Device (FED) is provided by a toroidal belt pumped limiter. Limiter design issues addressed in this paper are (1) poloidal location of the limiter belt, (2) shape of the limiter surface facing the plasma, and (3) whether the belt is pumped from one or both sides. The criteria used for evaluation of limiter configuration features were sensitivity to plasma-edge conditions and ease of maintenance and fabrication. The evaluation resulted in the selection of a baseline FED limiter that is located at the bottom of the device and has a flat surface with a single leading edge

Status of FED/INTOR electromagnetics

International Nuclear Information System (INIS)

Murray, J.G.

1983-02-01

This report provides a summary of the electromagnetic studies, calculations, and conclusions in the evolution of the base design of FED/INTOR (Fusion Engineering Device/International Tokamak Reactor). The electromagnetic feastures include the startup, control, disruptions, and design of structures. This report provides information concerning the evolution of the electromagnetic studies on FED and the justification for the eddy current design feature. The report shows that a major design feature required is the provision of a low induction and resistive path for toroidal currents to flow in the structures in order to provide self-stabilization and to manage the disruption energy dissipation

FED pumped limiter configuration issues

International Nuclear Information System (INIS)

Haines, J.R.; Fuller, G.M.

1983-01-01

Impurity control in the Fusion Engineering Device (FED) is provided by a toroidal belt pumped limiter. Limiter design issues addressed in this paper are (1) poloidal location of the limiter belt, (2) shape of the limiter surface facing the plasma, and (3) whether the belt is pumped from one or both sides. The criteria used for evaluation of limiter configuration features were sensitivity to plasma edge conditions and ease of maintenance and fabrication. The evaluation resulted in the selection of a baseline FED limiter that is located at the bottom of the device and has a flat surface with a single leading edge

Energy-efficient adjustable speed double inverter-fed woundrotor ...

African Journals Online (AJOL)

Energy-efficient adjustable speed double inverter-fed woundrotor induction motor ... at speeds up to double rated without the magnetic flux reducing is presented. ... Keywords: power, double-fed wound-rotor induction motor drive, steel and ...

Aliados, tránsfugas y barrilitos: las elecciones legislativas de 2010 en República Dominicana

Directory of Open Access Journals (Sweden)

Ana Belén BENITO SÁNCHEZ

2011-03-01

Full Text Available Este artículo analiza las claves explicativas de los resultados de las elecciones legislativas y municipales de 2010 en República Dominicana así como de la reciente transformación que ha experimentado el sistema de partidos dominicano, del tripartidismo al bipartidismo plural. El liderazgo del presidente Leonel Fernández, su imagen, popularidad y pragmatismo son la clave del éxito electoral del PLD, favorecido también por el faccionalismo endémico del PRD y la descomposición progresiva del PRSC. En esta contienda, el PLD consolida su dominio electoral gracias al apoyo de los partidos minoritarios y se asegura el control del Legislativo durante los próximos seis años.

El debate entre liberales y conservadores en Centroamérica : distintos medios para un objetivo connún, la construcción de una república de ciudadanos (1821-1900

Directory of Open Access Journals (Sweden)

Sonia Alda Mejías

2000-01-01

Full Text Available La aspiración común de los liberales y los conservadores en Centroamérica en el siglo XIX fue construir una república representativa de ciudadanos instruidos y formados. La diferencia radico en cómo realizar este proceso de transformación. Este debate determinó en buena parte la evolución de la ciudadanía y los diferentes modelos de república implantados a lo largo del siglo XIX en la región. Mediante el estudio comparado de la legislación electoral y los textos constitucionales se comprueba la existencia de tres modelos de república diferentes en coherencia con la forma en que ambos grupos concibieron la forma, el ritmo y los medios para lograr un objetivo compartido por ambos.The common goal of liberals and conservatives In Centroamérica during the nineteeth century was the construction of a representative republic constituted by formed and instructed citizens. Tfie difference among them was how to perform this transformation process. The debate determined basically the evolution of citizenship and the distinctive modela of republican order implanted during the century. Through the comparative analysis of electoral legislatlon and ttie Cartas Magnas can be preved tfie existence of three different republican models according withi tlie common goal of the two already mentioned groups.

FedScope Employment Cubes

Data.gov (United States)

Office of Personnel Management — This raw data set provides Federal civilian employee population data. The scope of this raw data set includes all data elements used in the creation of the FedScope...

Oil and Gas Emergency Policy: Germany 2012 update

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-07-01

Germany has very little domestic oil and natural gas production and relies heavily on imports. It has well diversified and flexible oil and natural gas supply infrastructure, which consists of crude, product and gas pipelines and crude and oil product import terminals. Natural gas is imported into Germany exclusively by cross-border pipeline. The country has no LNG infrastructure, although some German companies have booked capacities in overseas LNG terminals. Oil continues to be the main source of energy in Germany although it has declined markedly since the early 1970s. It now represents approximately 32% of Germany’s total primary energy supply (TPES). Natural gas consumption in Germany has declined 10% since 2006. Demand was 90 bcm in 2010, down from 100 bcm in 2005. According to government commissioned analysis, the total consumption of natural gas in Germany is expected to continue to decline over the long term. The share of natural gas in Germany’s TPES is currently around 22%. German oil stock levels are generally well above the required 90-days. Total oil stock levels in Germany were equivalent to 140 days net imports in April 2012. Since 1998, the German oil stockholding agency (EBV) has been solely responsible for meeting Germany's 90-day stockholding obligation. The Oil Stockholding Act stipulates that the EBV shall constantly maintain stocks of oil and petroleum products at a level equivalent to or above 90 days of net imports. There is no minimum stockholding obligation on industry, so industry held commercial stocks are held in addition to the EBV stocks. There are several legal tools available to German authorities for natural gas emergency response. These include Ordinances that can be used to restrict the sale, purchase or use of goods, both in terms of quantity and time, or permit them only for certain priority purposes, to ensure that vital energy needs are met. There are no compulsory natural gas storage requirements in Germany, and no

Recollections of a jewish mathematician in Germany

CERN Document Server

2016-01-01

Abraham A. Fraenkel was a world-renowned mathematician in pre–Second World War Germany, whose work on set theory was fundamental to the development of modern mathematics. A friend of Albert Einstein, he knew many of the era’s acclaimed mathematicians personally. He moved to Israel (then Palestine under the British Mandate) in the early 1930s. In his autobiography Fraenkel describes his early years growing up as an Orthodox Jew in Germany and his development as a mathematician at the beginning of the twentieth century. This memoir, originally written in German in the 1960s, has now been translated into English, with an additional chapter covering the period from 1933 until his death in 1965 written by the editor, Jiska Cohen-Mansfield. Fraenkel describes the world of mathematics in Germany in the first half of the twentieth century, its origins and development, the systems influencing it, and its demise. He also paints a unique picture of the complex struggles within the world of Orthodox Jewry in Germany....

A tracer test to determine a hydraulic connection between the Lauchert and Danube karst catchments (Swabian Alb, Germany)

Science.gov (United States)

Knöll, Paul; Scheytt, Traugott

2018-03-01

A dye tracer experiment was conducted between the rivers Lauchert and Danube near Sigmaringen (Swabian Alb, southern Germany). After a flood event in the River Lauchert, it was suspected that flood water infiltrated into the karst system and drained towards springs in the Danube Valley. A potential connection of the two rivers is provided by the margin of a tectonic graben crossing the valleys. The aim of the tracer experiment was to gain insight into the dominant groundwater flow direction as well as to study a possible preferential connection between the Lauchert surface catchment area and springs in the Danube Valley. After introducing sodium-fluorescein into the unsaturated zone, six springs in the Danube Valley and the River Lauchert itself were observed. Tracer breakthrough at three springs showed that these springs are fed by groundwater originating in the Lauchert surface catchment. Adjacent springs were not affected by the experiment, indicating a rather sharp divide between separate spring catchments. Analyses of tracer breakthrough curves suggest that springs with a tracer occurrence are fed by the same conduit system. It was possible to show that spring catchments in Sigmaringen reach significantly into the Lauchert surface catchment. As a consequence, a drinking-water supplier has changed its supply strategy. The results also help to explain significant differences between flood damage in the central and lower courses of the River Lauchert.

Emission reduction program in the unified Germany

International Nuclear Information System (INIS)

Kehr, M.; Emsperger, W.; Termuehlen, H.

1992-01-01

High population density and intense industrialization in both parts of Germany resulted in high specific power demands. The domestic availability of hard coal and lignite made coal-fired power plants the backbone of power generation in all of Germany. The unification of Germany has brought together two power generation systems with similar basic needs and concepts. However, forty years existence within different economic systems has resulted in a quite different status in regard to installed generating capacity, availability of various fuels and environmental standards. To bridge the existing gap in a relatively short time is a huge challenge for the utilities, the power generation and distribution industry as well as for the federal and state authorities

Checklist of earthworms (Oligochaeta: Lumbricidae) from Germany.

Science.gov (United States)

Lehmitz, Ricarda; Römbke, Jörg; Jänsch, Stephan; Krück, Stefanie; Beylich, Anneke; Graefe, Ulfert

2014-09-23

A checklist of the German earthworm fauna (Oligochaeta: Lumbricidae) is presented, including published data, data from reports, diploma- and PhD- theses as well as unpublished data from museum collections, research institutions and private persons. Overall, 16,000 datasets were analyzed to produce the first German checklist of Lumbricidae. The checklist comprises 46 earthworm species from 15 genera and provides ecological information, zoogeographical distribution type and information on the species distribution in Germany. Only one species, Lumbricus badensis Michaelsen, 1907, is endemic to Germany, whereas 41% are peregrine. As there are 14 species occurring exclusively in the southern or eastern part of Germany, the species numbers in German regions increase from north to south.

Growth and Reproduction of Artificially Fed Cnaphalocrocis medinalis

Directory of Open Access Journals (Sweden)

Jian XU

2012-09-01

Full Text Available The growth and reproduction of rice leaffolder, Cnaphalocrocis medinalis, fed on an artificial diet were studied. The results showed that the larvae were able to grow and pupate on the artificial diet. The durations of larvae and pupas of C. medinalis on the artificial diet were 28.1 d and 10.1 d, postponed 4.9 d and 1.7 d respectively, compared with those reared with rice leaves. The number of ovipositions was 41.6 per female, 26.2% higher than that fed on rice leaves. Survival rate curve of larvae was a descent function of mortality-age, with no significant differences from the curve of larvae fed on rice leaves. The net reproductive rate (Ro, intrinsic rate of increase (rm and finite rate of increase (λ of the population fed on diet were 17.6928, 0.0884 and 1.0924, respectively, and the mean generation time (T and double time (td were prolonged 4.9 d and 1.3 d in comparison with the treatment of rice leaves. Population trend index (I was 3.26, indicating a growing number of the population of C. medinalis fed on artificial diet.

Climate change impact and resilience in the electricity sector: The example of Austria and Germany

International Nuclear Information System (INIS)

Totschnig, G.; Hirner, R.; Müller, A.; Kranzl, L.; Hummel, M.; Nachtnebel, H.-P.; Stanzel, P.; Schicker, I.; Formayer, H.

2017-01-01

The purpose of this paper is to investigate the resilience of possible future electricity and heating systems in regard to climate change and fuel price shocks. The dynamical simulation model HiREPS of the Austrian and German electricity, heating and cooling sectors was used for this analysis. The electricity generation cost and changes in the required secured capacity were used as indicators for the resilience of the energy system. The results show, that the analysed changes in the natural gas price have larger impact on the electricity generation cost than weather variability between different years or climate change. Especially the fossil fuel based scenario showed high sensitivity to the gas price. Analysis of the required secured capacity shows, that in the last quarter of the 21st century the annual maximum residual loads are growing and are dominated by strong cooling demand peaks. Promoting passive cooling options, efficient building designs and options for a controlled down regulation of cooling devices seems to be advisable to avoid installing large thermal power plant backup capacities. The evaluated climate model simulations show only small changes in photovoltaic, wind and hydro power generation for 2051−2080 in Austria and Germany. - Highlights: • Natural gas price has larger impact on the electricity cost than climate variability. • End of 21st century the annual maximum load is set by summer cooling demand peaks. • Promoting passive cooling options is advisable to avoid large backup capacities. • Only small changes in photovoltaic, wind and hydro power generation up to 2080.

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Patrimonio arqueológico e identidades en la República Dominicana

Directory of Open Access Journals (Sweden)

Jorge Ulloa Hung

2009-03-01

Full Text Available Se abordan algunos de los principales problemas que presenta el estudio y conservación del patrimonio arqueológico de la República Dominicana a la luz de los nuevos retos y problemas que ha generado la globalización, así como de otras deformaciones impuestas por determinados procesos históricos y políticos dentro de la historia del país. El análisis también intenta hacer un llamado a la conservación y estudio del patrimonio arqueológico dominicano a la luz de nuevos conceptos y categorías usadas para el estudio del tema en el campo de la arqueología y la sociología, en especial, el punto de vista que prioriza la actividad de los agentes sociales. Por último, se intentan puntualizar aspectos que se consideran esenciales para generar una visión distinta en el abordaje del patrimonio arqueológico y que, a larga, podrían redundar en el desarrollo de una percepción distinta sobre la disciplina arqueol��gica en el país.

Effect of curing ingredients and vacuum packaging on the physico-chemical and storage quality of ready-to-eat Vawksa rep (smoked pork product) during refrigerated storage.

Science.gov (United States)

Deuri, Deepshikha; Hazarika, Pragati; Singh, Tarun Pal; Chhangte, Lalchamliani; Singh, Parminder; Talukder, Suman

2016-06-01

The present study was conducted for the development of ready-to-eat Vawksa rep (smoked pork product) and to study the synergistic effect of curing ingredients and vacuum packaging on the physico-chemical and storage quality during refrigerated storage at (4°C±1°C) for 15 days. Four different batches of Vawksa rep samples were prepared, i.e., T-1 (uncured, first cooked at 121°C for 15 min, and then smoked at 120°C for 30 min), T-2 (uncured, cooked, and smoked simultaneously at 120°C for 45 min), T-3 (cured, first cooked at 121°C for 15 min, and then smoked at 120°C for 30 min), and T-4 (cured, cooked, and smoked simultaneously at 120°C for 45 min). Cooking yield was significantly higher (pproduct) could be prepared easily with little technology up-gradation and with a negligible escalation of production cost.

Sky Subtraction with Fiber-Fed Spectrograph

Science.gov (United States)

Rodrigues, Myriam

2017-09-01

"Historically, fiber-fed spectrographs had been deemed inadequate for the observation of faint targets, mainly because of the difficulty to achieve high accuracy on the sky subtraction. The impossibility to sample the sky in the immediate vicinity of the target in fiber instruments has led to a commonly held view that a multi-object fibre spectrograph cannot achieve an accurate sky subtraction under 1% contrary to their slit counterpart. The next generation of multi-objects spectrograph at the VLT (MOONS) and the planed MOS for the E-ELT (MOSAIC) are fiber-fed instruments, and are aimed to observed targets fainter than the sky continuum level. In this talk, I will present the state-of-art on sky subtraction strategies and data reduction algorithm specifically developed for fiber-fed spectrographs. I will also present the main results of an observational campaign to better characterise the sky spatial and temporal variations ( in particular the continuum and faint sky lines)."

The Dual Half-Arc data structure: towards the universal B-rep data structure

DEFF Research Database (Denmark)

Anton, François; Bugoslawski, P.; Mioc, Darka

2014-01-01

, or more generally, the topology of any topological space. For this purpose, we generalize an existing data structure from 2D to 3D and design a new 3D data structure that realizes the synthesis between an existing 3D data structure (the Dual Half-Edge (See Footonote 1) data structure) and the generalized...... 3D Quad-Arc data structure, (See Footonote 2) and at the same time, improves the Dual Half-Edge towards a simpler and more effective representation of cell complexes through B-rep structures. We generalize the idea of the Quad-Arc data structure from 2D to 3D, but instead of transforming a simple...... edge of the Quad-Edge data structure to an arc with multiple points along it, we group together primal edges of the Dual Half-Edge that have the same dual Half-Edge vertex tags (volume tags) into one Dual Half-Arc whose dual is the common Dual Half-Edge and primal faces corresponding to dual...

40 Years MAGLEV Vehicles in Germany

OpenAIRE

Meisinger, Reinhold; Guangwei, Shu

2011-01-01

On May 6th 1971 the worldwide first MAGLEV vehicle was presented by Messerschmitt-Bölkow-Blohm (MBB) in Ottobrunn near Munich, Germany. Till the year 2000 different test and application MAGLEV vehicles followed, but no commercial use in Germany. Since December 31st 2002 the Shang-hai MAGLEV Transportation System is successfully in operation, as the worldwide first and only one commercial used MAGLEV line. The paper in honour of Prof. Dr.-Ing. Eveline Gottzein for her 80th birthday contains in...

Undergraduate medical education in Germany

Directory of Open Access Journals (Sweden)

Chenot, Jean-François

2009-04-01

Full Text Available The purpose of this article is to give international readers an overview of the organisation, structure and curriculum, together with important advances and problems, of undergraduate medical education in Germany. Interest in medical education in Germany has been relatively low but has gained momentum with the new "Regulation of the Licensing of Doctors" which came into effect in 2003. Medical education had required substantial reform, particularly with respect to improving the links between theoretical and clinical teaching and the extension of interdisciplinary and topic-related instruction. It takes six years and three months to complete the curriculum and training is divided into three sections: basic science (2 years, clinical science (3 years and final clinical year. While the reorganisation of graduate medical education required by the new "Regulation of the Licensing of Doctors" has stimulated multiple excellent teaching projects, there is evidence that some of the stipulated changes have not been implemented. Indeed, whether the medical schools have complied with this regulation and its overall success remains to be assessed systematically. Mandatory external accreditation and periodic reaccreditation of medical faculties need to be established in Germany.

Bioavailability of cadmium in rats fed various diets

International Nuclear Information System (INIS)

Rabar, I.; Kostial, K.

1981-01-01

Six-week-old female albino rats were fed rat diet or human foods 3 days before and 6 days after a single oral dose of 115 sup(m)Cd. All animals were killed 6 days after administration and the radioactivity in the whole body and in the gut-free carcass was determined in a double scintillation counter. Gut retentions were calculated as the difference: whole body minus carcass. All animals fed meat, bread or milk had much higher body retentions than animals fed rat diet. Our results point out the importance of nutritional factors in metal metabolism and toxicity. (orig./MG) [de

U.S. Rep. Dave Weldon looks at the U.S. Lab Destiny in the SSPF.

Science.gov (United States)

1999-01-01

In the Space Station Processing Facility, Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office, points out a feature to U.S. Rep. Dave Weldon (right) in the U.S. Lab, called 'Destiny.' In the far background is Dana Gartzke, the congressman's chief of staff. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

The Role of Western Germany in West European Defense

Science.gov (United States)

1966-04-08

Ralph. Modern German History. New York: E. P. Dutton & Co., Inc., 1964. (DD175 F5) 34. German Research Association. Germany: Franz Steiner Verlag Gmb...and Rudolf , Walter. This Germany. New York: New York Graphic Society Publishers, Ltd., 1954. (DD257 L42) 39. Heidenheimer, Arnold J. The Government...202-07, 243. 47. Lauder, K. H. A Brief Review of Science and Technoloc in Western Germany. London: HIISO, 1955. (Q18 G4G7) 48. Leonhardt, Rudolf Walter

48 CFR 252.229-7002 - Customs exemptions (Germany).

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Customs exemptions... of Provisions And Clauses 252.229-7002 Customs exemptions (Germany). As prescribed in 229.402-70(b), use the following clause: Customs Exemptions (Germany) (JUN 1997) Imported products required for the...

Effect of curing ingredients and vacuum packaging on the physicochemical and storage quality of ready-to-eat Vawksa rep (smoked pork product during refrigerated storage

Directory of Open Access Journals (Sweden)

Deepshikha Deuri

2016-06-01

Full Text Available Aim: The present study was conducted for the development of ready-to-eat Vawksa rep (smoked pork product and to study the synergistic effect of curing ingredients and vacuum packaging on the physico-chemical and storage quality during refrigerated storage at (4°C±1°C for 15 days. Materials and Methods: Four different batches of Vawksa rep samples were prepared, i.e., T-1 (uncured, first cooked at 121°C for 15 min, and then smoked at 120°C for 30 min, T-2 (uncured, cooked, and smoked simultaneously at 120°C for 45 min, T-3 (cured, first cooked at 121°C for 15 min, and then smoked at 120°C for 30 min, and T-4 (cured, cooked, and smoked simultaneously at 120°C for 45 min. Results: Cooking yield was significantly higher (p<0.05 for the T-4. The pH of T-3 and T-4 samples was significantly higher (p<0.05 on day 15. The tyrosine value of all the samples increased significantly (p<0.05 among the different days of analysis. Thiobarbituric acid value was significantly (p<0.05 lower in T-3 sample both at the beginning and at the end of storage period. In microbiological profile, total plate count was lower in T-3 and T-4 than T-1 and T-2. However, Escherichia coli count was negative for T-3 and T-4 samples throughout the storage period. Among sensory attributes, T-3 and T-4 samples registered superior scores for color, flavor, texture, juiciness, and overall acceptability. Conclusion: Furthermore, Vawksa rep (smoked pork product could be prepared easily with little technology up-gradation and with a negligible escalation of production cost.

provincia de Buenos Aires (República Argentina

Directory of Open Access Journals (Sweden)

Rubén Alberto Cervini

2008-01-01

Full Text Available En el estudio que se informa se investigaron las relaciones entre progreso de aprendizaje (valor agregado, motivación y autoconcepto académico del alumno en Matemática, en el marco de los efectos de las características socioeconómicas y académicas del alumno y de su escuela. Para la medición del valor agregado se utilizaron los resultados de dos pruebas estandarizadas de Matemática aplicadas a una cohorte de alumnos de la Provincia de Buenos Aires (República Argentina en dos momentos diferentes (séptimo y noveno años de Educación General Bási ca - EGB. Las mediciones de motivación y de autoconcepto se basaron en respuestas a ítemes binarios de actitudes con respecto a Ma temática y fueron definidas utilizando el análisis de la componente prin - cipal, a partir de la matriz de correlación tetracórica (método heurístico. Para el análisis de las correlaciones se utilizó la téc nica estadística de modelos multinivel. El presente estudio relaciona los resultados empíricos con la teoría del habitus de Bourdieu. Inicialmente, el autoconcepto resulta significativa y positivamente asociado con el puntaje en la prueba y con el progreso de aprendizaje posterior. Este efecto continúa siendo significati vo aun cuando se controlan los efectos del nivel socioeconómi - co y del género del alumno. Sin embargo, su capacidad ex plicativa es muy tenue desde el punto de vista práctico. Si bien este resultado confirmaría la hipótesis central de la teoría de la reproducción, indica un sendero a través del cual podrían producirse transformaciones. Uno de los desafíos del sistema educativo es promover el habitus escolar cultivado (autoconcepto más allá de las determinaciones sociales, culturales y económicas.

The role of Germany in resolving the ukrainian crisis

Directory of Open Access Journals (Sweden)

Olena L. Hilchenko

2016-02-01

Full Text Available The article analyzes the participation of Germany in the matter of the Ukrainian crisis 2013-2015 and presents some approaches to the definition of the term «Ukrainian crisis». Reveals the reasons that lead Germany to take an active position in solving the Ukrainian question. Characterized the evolution of German-Russian relations from 90s to 2014, within which examined the St. Petersburg dialogue, «Pact of Putin-Schroeder», «Weimar triangle», «Partnership for modernization», Russian-Georgian conflict 2008. Available analysis of the new strategy of German foreign policy in 2012 «to support globalization – develop partnerships to share responsibility» and a new paradigm of German foreign policy presented in 2014 in the framework of the Munich conference on security policy. Examines the role of Germany in the European integration process of Ukraine during the Euromaidan events, the signing of the Association Agreement of Ukraine with the EU, ratification and future prospects of the enlargement of the European Union through the Eastern partnership countries. Presents the results of the public opinion of the population of Germany on this issue. Analyzes the position of the Germany government regarding the annexation of Crimea, the illegal referendum in Donetsk and Lugansk regions and the military aggression of Russian Federation against Ukraine. Presents description of the Germany role in the process of the diplomatic settlement of the military conflict in the East Ukraine in the framework of Norman four. On the example of polls are considered the public opinion of the population of Germany concerning possible ways of settlement the Ukrainian crisis. Presents the official position of the President of the Federal Republic of Germany. J. Gauck, Chancellor Merkel, Foreign Minister Frank-V. Steinmeier and Minister of Finance Schaeuble on certain issues of the Ukrainian crisis and the prolongations of sanctions against the Russian Federation

Public perceptions of cohort studies and biobanks in Germany.

Science.gov (United States)

Starkbaum, Johannes; Gottweis, Herbert; Gottweis, Ursula; Kleiser, Christina; Linseisen, Jakob; Meisinger, Christa; Kamtsiuris, Panagiotis; Moebus, Susanne; Jöckel, Karl-Heinz; Börm, Sonja; Wichmann, H-Erich

2014-04-01

Cohort studies and biobank projects have led to public discussions in several European countries in the past. In Germany, many medium-sized studies are currently running successfully in terms of respondent rates. However, EU-wide research on general public perceptions of biobanks and cohort studies have shown that Germany is among those countries where people express the highest reluctance for providing body material and other data for research purposes. Because of early efforts of the just-initiated German National Cohort Study, we are able to begin to investigate in greater detail how various groups of people across Germany reflect and discuss the ongoing implementation of cohort studies and biobanking in Germany. Our research is based on 15 focus group discussions in four German regions, as well as on Eurobarometer poll data on biobanking.

Wind power report Germany 2014

International Nuclear Information System (INIS)

Rohrig, Kurt

2015-01-01

Record year 2014. In Germany, the expansion figures attained were so high on land and at sea that the overall new installation figure of 5,188 MW surpassed the previous maximum (from 2002) by more than 60%. With an overall capacity of 39,259 MW, for the first time, wind energy in Germany covers 9.7% of gross power consumption. On the global scale a capacity of more than 51,000 MW has been added - another record high for wind energy installations. Power mix. At 161 TWh, renewable energies in Germany covered 27.8% of gross power consumption and provided for the first time more energy than any other energy source. Coming into force of the new REA in August 2014, modified support schemes caused the expansion of biogas plants and large-scale PV installations to falter. The record expansion seen for wind energy can be interpreted as a pull-forward effect due to the tender procedures coming into force in 2017. Grid integration. Loss of production caused by feed-in management measures rose by 44% to 555 GWh as compared to 2012. Wind turbines were affected in 87% of cases but the impact on PV installations is increasing. Power generation must be more flexible and grids expanded to limit loss of production. Of the 23 expansion projects (1,887 km) in the Electricity Grid Expansion Act, just a quarter of them had been realized by the end of 2014 (463 km). In the preliminary analysis results for the 2014 grid development plan, the extent of grid upgrading and conversion was 3050 km. Offshore, the HelWin 1 grid link with a capacity of 580 MW went online. SylWin 1 and BorWin 2, with a total capacity of 1660 MW, are currently being tested in a trial. In the preliminary analysis results for the 2014 offshore grid development plan, grid connections having an overall capacity of 10.3 GW are planned. Onshore. 2014 saw a total of 44 different turbine types installed in Germany. For the first time, virtually the same number of turbines were added in the 3-4 MW class, as in the 2-3 MW

Greenhouse gas neutral Germany in 2050

International Nuclear Information System (INIS)

Benndorf, Rosemarie; Bernicke, Maja; Bertram, Andreas

2014-01-01

In order to answer the question how a greenhouse gas neutral Germany would look like an interdisciplinary process was started by the Federal Environmental Agency. It was clear from the beginning of this work that a sustainable regenerative energy supply could not be sufficient. Therefore all relevant emission sources were included into the studies: traffic, industry, waste and waste water, agriculture, land usage, land usage changes and forestry. The necessary transformation paths to reach the aim of a greenhouse gas neutral Germany in 2050, economic considerations and political instruments were not part of this study.

Nuclear power perspectives for Germany

International Nuclear Information System (INIS)

Anon.

1992-01-01

Approximately 300 experts from the power industries, of research and politics, from Germany and abroad followed the invitation of the Deutsches Atomforum (DAtF) to meet at the traditional winter meeting held in Bonn on January 28 and 29, 1992, in order to discuss topical political issues, not only relating to nuclear power, but to primary energy supply in general. Bonn having been chosen as the place for the 1992 meeting, there were unusually many members of Parliament and members of the Federal German Government attending the conference. The four sessions of the conference were devoted to the following aspects: Perspectives, the world energy market, current issues of energy policy in Germany, and preventive risk management. (orig.) [de

Report on nuclear power plant instrumentation and control in Germany

International Nuclear Information System (INIS)

Bastl, W.

1992-01-01

The paper describes the status of the NPP control and instrumentation in Germany. The general technology underlying most aspects of NPP C and I in Germany has not altered since the last progress report although there has been many improvements in detail. Since the beginning of 1990 the GRS carried out the safety investigations of NPPs in East Germany. The USSR as the vendor of the plants and France were also involved in the project. The following fields are briefly described: Status of nuclear power in Germany; training simulators; backfitting of computers and information systems; operator support/new control rooms. (author). 6 refs, 1 tab

Year 2 of Germany's Energy Transition

International Nuclear Information System (INIS)

Cruciani, Michel

2013-01-01

After a decade characterised by the take-off of renewable energies, Germany decided in 2010 to make them the top priority. At the same time, it decided to make exemplary efforts in terms of energy efficiency and the reduction of greenhouse gases. The audacious nature of this policy was strengthened by the 'turn' taken in 2011 to give up nuclear energy in the wake of the Fukushima accident. Given the initial results for 2012, Germany seems to be on target for reaching its national objective, of 18% renewable energy within total consumption by 2020. Germany is also well placed to reduce its planned cut in electricity consumption of 10%. The country will also meet its commitments, both international and European, concerning greenhouse gas emissions. In contrast, recent trends suggest it will be increasingly difficult for Germany to meet its own, domestic goal of cutting emissions by 40%, by 2020. Furthermore, it is hard to see how Germany will be able to bring down total energy consumption by 20% by 2020 (from 2008 levels), or increase the share of renewables in electricity production above 35%. Success with this latter objective is largely dependent on reinforcing networks, both for transmission over long distances and for local distribution. It is not sure that the delays accumulated in both areas will be made up for by 2020, despite the rapid legislative adjustments that have already been made. By favouring intermittent energy sources - wind and solar power - Germany also faces problems of managing frequent production fluctuations. The long term solution to this lies in storing electricity. However, despite the considerable efforts in research and development, the technologies necessary for this will doubtless not be available on a large scale before the end of the present decade. These efforts could nevertheless provide German industry with interesting advantages in sectors of high potential, such as electric vehicles. Measures to promote renewable energies are

Proceedings of FED remote maintenance equipment workshop

International Nuclear Information System (INIS)

Sager, P.; Garin, J.; Hager, E.R.; Spampinato, P.T.; Tobias, D.; Young, N.

1981-11-01

A workshop was convened in two sessions in January and March 1981, on the remote maintenance equipment for the Fusion Engineering Device (FED). The objectives of the first session were to familiarize the participants with the status of the design of the FED and to develop a remote maintenance equipment list for the FED. The objective of the second session was to have the participants present design concepts for the equipment which had been identified in the first session. The equipment list was developed for general purpose and special purpose equipment. The general purpose equipment was categorized as manipulators and other, while the special purpose equipment was subdivided according to the reactor subsystem it serviced: electrical, magnetic, and nuclear. Both mobile and fixed base manipulators were identified. Handling machines were identified as the major requirement for special purpose equipment

Las relaciones culturales de España en tiempo de crisis: de la II República a la Guerra Mundial

Directory of Open Access Journals (Sweden)

Lorenzo Delgado Gómez-Escalonilla

1994-01-01

Full Text Available En los primeros meses de 1936 el personal de la Junta de Relaciones Culturales preparaba la memoria correspondiente al año anterior. Se daba continuidad con ella a la difusión de las actividades del organismo, comenzada tras el establecimiento de la II República, y que contaba ya con las publicaciones relativas a los años 1931-1933 y 1934. Esa preocupación por divulgar los resultados de su labor era una muestra más del dinamismo que había adquirido la Junta de Relaciones Culturales después de la reforma que experimentó en 1931. También recordaba a la actuación de la Junta para Ampliación de Estudios, que editaba sistemáticamente las memorias de sus actividades para dejar constancia pública del trabajo realizado. La analogía a este respecto no era casual. Con la república los intelectuales reformistas procedentes de la Institución Libre de Enseñanza, que tiempo atrás inspiraron la creación de la Junta para Ampliación de Estudios, habían recuperado el predicamento sobre la planificación de la política cultural con el extranjero. Pero la memoria de la Junta del año 1935 nunca llegó a aparecer. La guerra civil se cruzó en el camino de quienes la redactaban.

Conference on participatory wind energy in France and in Germany

International Nuclear Information System (INIS)

Vohrer, Philipp; Poize, Noemie; Hanus, Dominik; Hallmann, Dieter; Jourdain, Pierre; Ruehl, Martin; Bessiere, Patrick; Guyonnet-Duperat, Philippe; Foerster, Maelle; Partetzke, Matthias; Rumolino, Claudio

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on participatory wind energy in France and in Germany. In the framework of this French-German exchange of experience, about 150 participants exchanged views on the role and involvement of citizens in wind energy projects and raised the question of the prerequisite to the construction of a participatory wind farm. In this framework, the different participatory models existing in both countries were analysed, in particular with regard to their respective advantages and drawbacks and to a legal framework which remains to be defined. Four projects, 2 in France and 2 in Germany, were presented as examples. The call for proposals model was presented and debated as well as the question of the project success, and of its financing and profitability. This document brings together the available presentations (slides) made during this event: 1 - Community wind farms in Germany: status quo and forecast (Philipp Vohrer); 2 - Participatory projects in France: which legal solutions, which prospects for development? (Noemie Poize); 3 - Citizen owned wind farms and their legal forms in Germany: Advantages and challenges of the different schemes (Dominik Hanus); 4 - Make wind power profitable: Citizen participation in Germany and France/Make the energy transition together. The energy co-operative participation as a model in Germany (Dieter Hallmann); 5 - Power to the people - A new model for French wind energy. Beganne community-owned wind farm (Pierre Jourdain); 6 - Making wind power profitable: civic participation in Germany and France: German utility companies rely on wind power. Direct civic participation in the municipal utility company - democratization of the turnaround in energy policy (Martin Ruehl); 7 - French municipalities get involved: calls for projects (Patrick Bessiere); 8 - Crowd-funding - French regulatory framework (Philippe Guyonnet-Duperat, Maelle Foerster); 9 - Making wind energy

[Performance of in vitro fertilization in Germany].

Science.gov (United States)

van der Ven, Hans; Montag, Markus; van der Ven, Katrin

2002-07-01

In Germany the application of assisted reproductive techniques (ART) is regulated by federal legislation. Compared with the international situation the "German Embryo Protection Law" is very "restrictive" and various methods of ART are prohibited, e.g. oocyte/embryo donation, embryo cryopreservation and Preimplantation Genetic Diagnosis (PGD). Furthermore, in Germany only 1 to 3 fertilized oocytes may be cultured to embryo. All these embryos then have to be transferred into the uterus of a particular patient. Additional fertilized oocytes can only be cryopreserved in a pronuclear state. The success rate of ART has increased significantly over the past few years owing to the introduction of blastocyst cultures and the selection of 1 to 2 good quality blastocysts for embryo transfer. Furthermore, the transfer of only 1 to 2 blastocysts effectively reduces the risk of high rank multiple pregnancies. In Germany, however, the selection of only a few good quality blastocysts for transfer is prohibited by law. New laboratory techniques, e.g. pronuclear scoring and polar body biopsy screening for aneuploidy are in accordance with German law. The application of these methods provides a selection of "good quality oocytes" and seems to increase the overall success rate. Further studies are required, however. The success rate, quality and cost effectiveness of ART in Germany appears compromised when compared with many other countries. What is more, in contrast to the international situation research and development in ART in Germany has been decreasing constantly over the past few years, due to the inappropriate regulations of the German health care system and the insufficient support given to university-based centers.

Chart context menu

African Journals Online (AJOL)

China, 4. Colombia, 4. Curaçao, 1. Ecuador, 1. Egypt, Arab Rep. 1. Ethiopia, 6. Finland, 2. France, 6. Germany, 6. Ghana, 2. Greece, 1. India, 37. Indonesia, 1. Ireland, 3. Italy, 5. Jamaica, 2. Jersey, 1. Kenya, 13. Korea, Republic of, 1. Lebanon, 1. Lesotho, 3. Malawi, 1. Malaysia, 3. Maldives, 1. Malta, 2. Mauritius, 1. Mexico, 1.

Deep Geothermal Energy Production in Germany

Directory of Open Access Journals (Sweden)

Thorsten Agemar

2014-07-01

Full Text Available Germany uses its low enthalpy hydrothermal resources predominantly for balneological applications, space and district heating, but also for power production. The German Federal government supports the development of geothermal energy in terms of project funding, market incentives and credit offers, as well as a feed-in tariff for geothermal electricity. Although new projects for district heating take on average six years, geothermal energy utilisation is growing rapidly, especially in southern Germany. From 2003 to 2013, the annual production of geothermal district heating stations increased from 60 GWh to 530 GWh. In the same time, the annual power production increased from 0 GWh to 36 GWh. Currently, almost 200 geothermal facilities are in operation or under construction in Germany. A feasibility study including detailed geological site assessment is still essential when planning a new geothermal facility. As part of this assessment, a lot of geological data, hydraulic data, and subsurface temperatures can be retrieved from the geothermal information system GeotIS, which can be accessed online [1].

Managing ageing workforces: Empirical evidence from Germany

OpenAIRE

Drew, H.

2013-01-01

Demographic change (ageing populations and falling birth rates) affects all industrialised nations, including Germany. Traditionally, the problems associated with managing numbers of older workers were mitigated by the Altersteilzeitgesetz in Germany. Under this law, firms were offered financial support by the government to offer early retirement (Müller-Camen et al. 2009). As these provisions came to an end in 2010, the need to find alternative solutions to displacing older workers, as well ...

Inequality-adjusted gender wage differentials in Germany

OpenAIRE

Selezneva, Ekaterina; Van Kerm, Philippe

2013-01-01

This paper exploits data from the German Socio-Economic Panel (SOEP) to re-examine the gender wage gap in Germany on the basis of inequality-adjusted measures of wage differentials which fully account for gender differences in pay distributions. The inequality-adjusted gender pay gap measures are significantly larger than suggested by standard indicators, especially in East Germany. Women appear penalized twice, with both lower mean wages and greater wage inequality. A hypothetical risky inve...

Persistent Educational Advantage Across Three Generations: Empirical Evidence for Germany

Directory of Open Access Journals (Sweden)

Andrea Ziefle

2016-12-01

Full Text Available This article uses survey data from the German Socio-Economic Panel (GSOEP to analyze the persistence of educational attainment across three generations in Germany. I obtain evidence of a robust effect of grandparents' education on respondents' own educational attainment in West Germany, net of parental class, education, occupational status, family income, parents' relationship history, and family size. I also test whether the grandparent effect results from resource compensation or cumulative advantage and find empirical support for both mechanisms. In comparison, the intergenerational association between grandparents' and respondents' education is considerably weaker in East Germany and is also mediated completely by parental education. There are hardly any gender differences in the role of grandparents for respondents’ educational attainment, except for the fact that resource compensation is found to be exclusively relevant for women’s attainment in both West Germany and in East Germany after German reunification and the associated transition to an open educational system.

Las relaciones culturales de España en tiempo de crisis: de la II República a la Guerra Mundial

OpenAIRE

Lorenzo Delgado Gómez-Escalonilla

1994-01-01

En los primeros meses de 1936 el personal de la Junta de Relaciones Culturales preparaba la memoria correspondiente al año anterior. Se daba continuidad con ella a la difusión de las actividades del organismo, comenzada tras el establecimiento de la II República, y que contaba ya con las publicaciones relativas a los años 1931-1933 y 1934. Esa preocupación por divulgar los resultados de su labor era una muestra más del dinamismo que había adquirido la Junta de Relaciones ...

La República Federal de Alemania ante el fin de las dictaduras ibéricas (1974-1976): miradas entrecruzadas

OpenAIRE

Sanz Díaz, Carlos

2012-01-01

El papel protagonista de la República Federal de Alemania, por medio principalmente de su gobierno, partidos y fundaciones políticas, y sindicatos, en las transiciones ibéricas ha sido puesto de manifiesto desde los primeros estudios sobre la dimensión internacional de los cambios de régimen político en Portugal y España en 1974-1975. Este artículo pretende contribuir al conocimiento del «factor alemán» en las transiciones ibéricas subrayando la percepción que se tenía desde Bonn de la peníns...

Las relaciones entre la República Federal Alemana y el Régimen Franquista tras la Segunda Guerra Mundial a través de la prensa española (1945-1958

Directory of Open Access Journals (Sweden)

Inés Ruiz Escudero

2009-12-01

Full Text Available Al comenzar la década de los cincuenta las relaciones hispano- germanas iniciaban una nueva andadura de la mano de la nueva situación internacional. España seguía apareciendo como un residuo del ya vencido fascismo, mientras que la recién creada República Federal Alemana iniciaba de la mano de Adenauer el camino hacia su recuperación nacional. En este sentido, las relaciones mantenidas durante la época hitleriana fueron consideradas un tema tabú que pocos se atrevieron a nombrar. Sin embargo, el restablecimiento de las Embajadas y el incremento de los contactos económicos y culturales propiciarían una rápida normalización de las relaciones entre ambos países, siempre apelando a su “tradicional amistad” iniciada ya en los tiempos del emperador Carlos V._______________________ABSTRACT:In the first decade of 1950, the Hispanic – German relationship led to the emergence of a new tendency provided by the new international context. Spain kept being a residual of the fascism, while the recently created Federal Republic of Germany began, thanks to Adenauer, its way to the national comeback. In this sense, all the relations managed during the regime, were considered a taboo that just a few reminded. Despite this, the reestablishment of Embassies and the increasing of economic and cultural bonds allowed a quick normalization of the relations in both countries, always appealing to that old, traditional friendship began under Charles V.

U.S. Rep. Dave Weldon looks at the U.S. Lab Destiny in the SSPF.

Science.gov (United States)

1999-01-01

In the cockpit of the orbiter Atlantis, which is in the Orbiter Processing Facility, Laural Patrick (left), a systems engineer with MEDS, points out a feature of the newly installed Multifunction Electronic Display Subsystem (MEDS), known as the 'glass cockpit,' to U.S. Rep. Dave Weldon. The congressman is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. He was in Palmdale, Calif., when Atlantis underwent the modification and he wanted to see the final product. The full-color, flat-panel MEDS upgrade improves crew/orbiter interaction with easy-to-read, graphic portrayals of key flight indicators like attitude display and mach speed. The installation makes Atlantis the most modern orbiter in the fleet and equals the systems on current commercial jet airliners and military aircraft. Atlantis is scheduled to fly on mission STS- 101 in early December.

Tritium transport and control in the FED

International Nuclear Information System (INIS)

Rogers, M.L.

1981-01-01

The tritium systems for the FED have three primary purposes. The first is to provide tritium and deuterium fuel for the reactor. This fuel can be new tritium or deuterium delivered to the plant site, or recycled DT from the reactor that must be processed before it can be recycled. The second purpose of the FED tritium systems is to provide state-of-the-art tritium handling to limit worker radiation exposure and to minimize tritium losses to the environment. The final major objective of the FED tritium systems is to provide an integrated system test of the tritium handling technology necessary to support the fusion reactor program. Every effort is being made to incorporate available information from the Tritium System Test Assembly (TSTA) at Los Alamos National Laboratory, the Tokamak Fusion Test Reactor (TFTR) tritium systems, and the tritium handling information generated within DOE for the past 20 years

Germany as an energy-producing country - quo vadis?

International Nuclear Information System (INIS)

Rauscher, K.

2003-01-01

Secure, sufficient electricity supplies available at any time, as guaranteed in Germany, are vital to the existence of our modern society. Under the conditions of deregulated markets, it must continue to be possible in Germany to offer reliable, economical and non-polluting energy supplies. These three factors should enjoy equal importance in energy policy decisions in the interest of sustainability. The skewed balance caused by political preferences as experienced at the present time can jeopardize the general objective of optimization of the three factors in the long run. As in no other country, the power industry in Germany had to make a considerable adaptation effort, inter alia, because of market deregulation, airborne pollutant reduction, and agreements on the operating life of existing nuclear power plants. Other problems are likely to arise in the near future, e.g. in connection with emission trading. The power industry is willing and able to solve these future problems. This is true in particular of the expected replacement of power plants of approx. 40 000 MW generating capacity in Germany, where the European framework must be taken into account with a replacement requirement of approx. 200 000 MW. This implies investments of euro 50 billion in Germany alone, which can be made only if there is sufficient security in planning for the operators of power plants. The choice of efficient and economically viable power generation technologies must be possible in this respect. (orig.) [de

Maternal Employment and Childhood Overweight in Germany

OpenAIRE

Sophie-Charlotte Meyer

2015-01-01

A widespread finding among studies from the US and the UK is that maternal employment is correlated with an increased risk of child overweight, even in a causal manner, whereas studies from European countries obtain less conclusive results. As evidence for Germany is still scarce, the purpose of this study is to identify the effect of maternal employment on childhood overweight in Germany using two sets of representative micro data. Moreover, we explore potential underlying mechanisms that mi...

Climate protection policy. On Germany's pioneer role

International Nuclear Information System (INIS)

Kuebler, Knut

2014-01-01

After a downward trend of many years Germany's energy-related CO 2 emissions have risen again slightly over the past two years. This increase has prompted the federal government to initiate a new climate protection action campaign. After almost 30 years of experience in the field of climate protection policy there is every reason for Germany to be more consistent in using its political scope to act on the unrestrained increase in global greenhouse gas emissions.

Educación en medios de comunicación en Alemania: desarrollo y situación actual Media education in Germany: development and current situation

Directory of Open Access Journals (Sweden)

Gerhard Tulodziecki

2007-03-01

Full Text Available Este trabajo analiza de las diferentes tendencias y del estado actual de la enseñanza de los medios de comunicación en la República Federal de Alemania. La educación en medios de comunicación en Alemania se centra en la actualidad en el debate sobre cómo usar esa gran variedad de medios que tenemos a nuestra disposición, con unos fines verdaderamente educativos y fundamentados metodológicamente. Se observa, en relación a este tema, que hay no sólo diferentes ideas conceptuales, sino también diferentes proyectos de investigación y desarrollo, que se ocupan principalmente de las aplicaciones prácticas y de un acercamiento a los colegios, a los programas de formación del profesorado y a otros contextos educativos. This paper analyses the different trends in the current situation of media education in Germany. The discussion point is how to use the large variety of media we have in order to get really educative aims with a scientific basis. The German media education landscape shows not only a lot of different concepts but also a large number of projects on teacher training, school approaching and practical applications.

The outlook for natural gas in Germany

International Nuclear Information System (INIS)

Bergmann, B.

1993-01-01

In a generally stagnant energy market, gas will be the energy with the highest growth rate in Germany, especially because of its steadily rising shares in the residential and commercial sector. In western Germany there is to be accepted that the demand forecasts, which were raised from one conference to the next, have passed their zenith. Great uncertainty exists as regards the future use of gas for power generation. In the absence of any significant expansion of this market sector, which is considered rather improbable in western Germany, it can be stated that anticipated gas demand up to the year 2005 is already covered by existing import contracts and scheduled domestic production. The picture is completely different in eastern Germany, where a doubling of consumption is quite feasible. To achieve the requisite diversification of supplies, substantial additional imports from western sources will have to be contracted. Russia can and should remain eastern Germany's main supplier in the long run, but Russian deliveries must be placed on a reliable, long-term contractual basis. As far as new gas projects are concerned, deliveries from Norway, to a limited extent from the United Kingdom and above all as part of the new Russian export initiative are under discussion. Generally speaking, transit will be an increasingly significant issue, especially for additional supplies from Russia. The efficiency and reliability of gas marketing companies will become far more important in an environment characterised by growing uncertainties. The reliable customer offering a dependable market outlet will be increasingly sought. With energy prices likely to increase only slightly, the management of uncertainties and the safeguarding of economic driving forces will be the main challenge facing our supply projects. 15 figs

ANALISIS PENGARUH HARGA MINYAK DUNIA DAN FED FUNDS RATE TERHADAP INFLASI INDONESIA

Directory of Open Access Journals (Sweden)

Masadi Masadi

2017-06-01

Full Text Available Perubahan pola siklus ekonomi global dapat mempengaruhi inflasi Indonesia melalui jalur perdagangan dan melalui jalur pasar keuangan, seperti harga minyak dunia dan Fed Funds Rate. Penelitian ini bertujuan untuk menganalisis pengaruh langsung maupun tidak langsung yang disebabkan perubahan harga minyak dunia dan Fed Funds Rate terhadap volatilitas inflasi Indonesia. Alat analisis yang digunakan dalam penelitian ini adalah dengan menggunakan analisis jalur. Hasil penelitian menunjukan bahwa terdapat pengaruh langsung dan signifikan variabel harga minyak dunia terhadap inflasi, terdapat pengaruh langsung dan signifikan variabel Fed Funds Rate terhadap inflasi, terdapat pengaruh langsung dan signifikan variabel BI rate terhadap inflasi, variabel jumlah uang beredar tidak berpengaruh secara langsung dan tidak signifikan terhadap inflasi Indonesia, terdapat pengaruh langsung dan signifikan variabel harga minyak dunia dan Fed Funds Rate terhadap jumlah uang beredar, terdapat pengaruh langsung dan signifikan variabel Fed Funds Rate terhadap jumlah uang beredar, terdapat pengaruh langsung dan signifikan variabel harga minyak dunia terhadap BI rate, terdapat pengaruh langsung dan signifikan variabel Fed Funds Rate terhadap BI rate. Adapun pengaruh tidak langsung hanya variabel Fed Funds Rate dengan variabel intervening BI rate yang berpengaruh signifikan terhadap inflasi. Changing patterns of global economic cycles may affect inflation Indonesia through trade and financial markets, such as oil prices and Fed Funds Rate. This study aimed to analyze the effect directly or indirectly caused changes in world oil prices and the Fed Funds Rate to the volatility of inflation in Indonesia. The analytical tool used in this research is by using path analysis. The results showed that there are significant direct and signifian variables in world oil prices n inflation, there is a direct influence and signifian variables Fed Funds Rate on inflation, there is a direct

High-resolution observations in the western Mediterranean Sea: the REP14-MED experiment

Science.gov (United States)

Onken, Reiner; Fiekas, Heinz-Volker; Beguery, Laurent; Borrione, Ines; Funk, Andreas; Hemming, Michael; Hernandez-Lasheras, Jaime; Heywood, Karen J.; Kaiser, Jan; Knoll, Michaela; Mourre, Baptiste; Oddo, Paolo; Poulain, Pierre-Marie; Queste, Bastien Y.; Russo, Aniello; Shitashima, Kiminori; Siderius, Martin; Thorp Küsel, Elizabeth

2018-04-01

The observational part of the REP14-MED experiment was conducted in June 2014 in the Sardo-Balearic Basin west of Sardinia (western Mediterranean Sea). Two research vessels collected high-resolution oceanographic data by means of hydrographic casts, towed systems, and underway measurements. In addition, a vast amount of data was provided by a fleet of 11 ocean gliders, time series were available from moored instruments, and information on Lagrangian flow patterns was obtained from surface drifters and one profiling float. The spatial resolution of the observations encompasses a spectrum over 4 orders of magnitude from 𝒪(101 m) to 𝒪(105 m), and the time series from the moored instruments cover a spectral range of 5 orders from 𝒪(101 s) to 𝒪(106 s). The objective of this article is to provide an overview of the huge data set which has been utilised by various studies, focusing on (i) water masses and circulation, (ii) operational forecasting, (iii) data assimilation, (iv) variability of the ocean, and (v) new payloads for gliders.

Chikungunya en la República Dominicana: lecciones aprendidas en los primeros seis meses

Directory of Open Access Journals (Sweden)

Raquel Pimentel

2014-11-01

Full Text Available La epidemia de chikungunya en la República Dominicana se inició en febrero de 2014. En los primeros seis meses se registraron 429 421 casos, que representaron 65% de todos los notificados a la Organización Panamericana de la Salud por 33 países y territorios de la Región de las Américas. Esta epidemia se ha transmitido con rapidez en dicho país y ha demandado una intensa respuesta intersectorial, que ha liderado el Ministerio de Salud Pública y, especialmente, el Sistema Nacional de Vigilancia Epidemiológica y la red de los servicios de salud. Considerando que afectará a miles de personas, el objetivo de este artículo es describir las actuaciones realizadas y compartir los resultados y las lecciones aprendidas durante estos primeros meses con los ministerios de salud y los profesionales de los países de la Región para ayudarles a preparar una respuesta adecuada para afrontarla de forma efectiva y eficiente.

Educational Systems and Rising Inequality: Eastern Germany after Unification

Science.gov (United States)

von Below, Susanne; Powell, Justin J. W.; Roberts, Lance W.

2013-01-01

Educational systems considerably influence educational opportunities and the resulting social inequalities. Contrasting institutional regulations of both structures and contents, the authors present a typology of educational system types in Germany to analyze their effects on social inequality in eastern Germany after unification. After 1990, the…

From Fed-batch to Continuous Enzymatic Biodiesel Production

DEFF Research Database (Denmark)

Price, Jason Anthony; Nordblad, Mathias; Woodley, John M.

2015-01-01

In this this paper, we use mechanistic modelling to guide the development of acontinuous enzymatic process that is performed as a fed-batch operation. In this workwe use the enzymatic biodiesel process as a case study. A mechanistic model developedin our previous work was used to determine...... measured components (triglycerides, diglycerides, monoglycerides, free fatty acid and fatty acid methyl esters(biodiesel)) much better than using fed-batch data alone given the smaller residuals. We also observe a reduction in the correlation between the parameters.The model was then used to predict that 5...... reactors are required (with a combined residence time of 30 hours) to reach a final biodiesel concentration within 2 % of the95.6 mass % achieved in a fed-batch operation, for 24 hours....

Secretion of hepatic triglycerides into plasma of rats fed retinol

International Nuclear Information System (INIS)

Ahuja, H.C.; Misra, U.K.

1975-01-01

The effect of feeding 33 mg of retinol daily for two days on liver and plasma lipids of rats has been studied. The secretion of liver TG into plasma of retinol fed rats has been measured by the use of palmitic acid-1- 14 C and of Triton WR 1339. Liver and plasma lipids, TG, phospholipids and PC were significantly higher in retinol fed rats as compared to control rats. The incorporation of palmitic acid-1- 14 C into liver TG, PC and PE was significantly higher in retinol fed rats. The labelling pattern with time of liver and plasma TG and PC shows that the secretion of liver TG and PC into plasma was impaired in retinol fed rats. (auth.)

Wind power in Germany - a success story

International Nuclear Information System (INIS)

Weller, T.

1996-01-01

The successful introduction of wind power to the electric power industry in the Federal Republic of Germany is described using graphic representations to illustrate the industry's growth over the last twenty years. The history of the wind market is discussed, together with the importance of stakeholders as a way of funding the industry. The author concludes that public support for environmentally sensitive power generation was the key factor leading to the success of the wind power industry in Germany. (UK)

Housing Markets in Austria, Germany and Switzerland

OpenAIRE

Martin Schneider; Karin Wagner

2015-01-01

Running counter to the sharp rise in house prices and housing wealth observed since the mid- 1990s in the vast majority of European countries, real house prices in Germany and Austria were going down in this period and did not start to rise until 2010 or 2007, respectively. This reflects national idiosyncracies in housing markets and motivated the discussion of relevant peculiarities in, and similarities among, Austria and Germany as well as Switzerland. Among the most important structural fe...

Tax wedge in Croatia, Belgium, Estonia, Germany and Slovakia

Directory of Open Access Journals (Sweden)

Ana Gabrilo

2016-06-01

Full Text Available The aim of this paper is to analyse the taxation of labour income in Croatia, Belgium,Estonia, Germany and Slovakia. Having presented an outline of tax system rules, the paper shows the decomposition of the net average tax wedge for different family types and different income levels based on the OECD methodology. The results show that all observed countries apply a progressive tax schedule, apart from Germany where taxation for higher gross wages is not progressive due to a  cap on the SIC base. When it comes to a taxpayer earning an average gross wage, a Croatian single worker without children has the lowest tax burden, followed by Estonia, Slovakia, Germany and Belgium. However, as regards taxpayers earning 400% of AGW, Estonia has the smallest tax wedge, followed by Slovakia, Germany, Croatia and Belgium. Similar results are obtained by analyzing the tax wedge for couples with two children where one spouse is out of work.

Rewriting Germany's nuclear law

International Nuclear Information System (INIS)

Roser, T.

1992-01-01

In Germany, the private use of nuclear energy for peaceful uses is strictly regulated by a Nuclear Energy Act. Since its enactment back in 1959, this legislation has been overhauled five times - most recently in 1985. Now Klaus Toepfer, Germany's Federal Minister for the Environment, Protection of Nature, and Nuclear Safety, has set out to revise the Act for the sixth time. The present draft bill is intended to reorganise the back end of the nuclear fuel cycle; eliminate public promotion of nuclear power; clarify points of legal dispute. Of the draft bill's three aims, the last two are more parochial. The real novelty lies in the changes to the rules for the back end of the fuel cycle. First, the Federal Government proposes to abandon the priority given to spent fuel recycling. In future, direct disposal will be an equivalent option, and waste avoidance will have top priority. Intimately linked to the back end proposal is the Government's plan to load on the shoulders of nuclear operators the full responsibility for building and operating repositories for the final disposal of nuclear waste. The third aspect of Government's back end plans concerns decommissioning. At present, operators accumulate provisions over the plant lifetime, which for that purpose is estimated at 19 years. The provisions vary from plant to plant but are generally around DM1 billion and are tax free. Under the proposed regulations, this sum must be available from the first day of operation to cover the case of an early shutdown. In practice, this will increase the initial investment for a nuclear power plant in Germany by 10-20% and so make nuclear power less competitive. (author)

Nuclear power in Germany

International Nuclear Information System (INIS)

Schaefer, A.

1990-01-01

I want to give some ideas on the situation of public and utility acceptance of nuclear power in the Federal Republic of Germany and perhaps a little bit on Europe. Let me start with public perception. I think in Germany we have a general trend in the public perception of technology during the last decade that has been investigated in a systematic manner in a recent study. It is clear that the general acceptance of technology decreased substantially during the last twenty years. We can also observe during this time that aspects of the benefits of technology are much less reported in the media, that most reporting by the media now is related to the consequences of technologies, such as negative environmental consequences. hat development has led to a general opposition against new technological projects, in particular unusual and large. That trend is related not only to nuclear power, we see it also for new airports, trains, coal-fired plants. here is almost no new technological project in Germany where there is not very strong opposition against it, at least locally. What is the current public opinion concerning nuclear power? Nuclear power certainly received a big shock after Chernobyl, but actually, about two thirds of the German population wants to keep the operating plants running. Some people want to phase the plants out as they reach the end-of-life, some want to substitute newer nuclear technology, and a smaller part want to increase the use of nuclear power. But only a minority of the German public would really like to abandon nuclear energy

Nuclear third party liability in Germany

International Nuclear Information System (INIS)

Raetzke, Christian

2016-01-01

The German system of nuclear third party liability has always been, and arguably still is, the object of considerable interest in the international nuclear law community. This may seem surprising since Germany adheres to the Paris Convention and is therefore a party to a community of 15 states all following the same principles enshrined in this Convention. In fact, when implementing the PC, Germany chose the approach ensuring the most literal adherence to the PC's principles: it adopted the PC in its entirety, thus directly transposing the PC text into binding German law, instead of enacting a national law derived from, but not literally translating, the PC. At the same time, perhaps no other nation has made use of the options, choices and margins offered or abandoned by the PC to the national legislators, or kept in store by way of a reservation at signature of the Convention, in such an extended manner, testing - and as has even been contended in the past: stressing - the boundaries of the PC system. Unlimited liability introduced in 1985, the highest financial security of any PC state (EUR 2.5 billion), unlimited territorial scope combined with the principle of reciprocity and liability of German operators even in the force majeure cases of Article 9 of the PC are probably the most interesting decisions made by Germany in this context, established in the Atomic Energy Act (Atomgesetz). These choices betray a certain tendency of the German government to give the greatest possible benefit to victims, and in parallel to achieve a 'normalisation' of the nuclear liability regime, without stifling the industry. Within the compromise underlying the international nuclear liability regime - enabling the nuclear industry to create and sustain an energy sector highly relevant for national electricity production on the one hand and protecting potential victims on the other - Germany has more and more shifted the balance, as far as practically possible, to the

Aspartame-fed zebrafish exhibit acute deaths with swimming defects and saccharin-fed zebrafish have elevation of cholesteryl ester transfer protein activity in hypercholesterolemia.

Science.gov (United States)

Kim, Jae-Yong; Seo, Juyi; Cho, Kyung-Hyun

2011-11-01

Although many artificial sweeteners (AS) have safety issues, the AS have been widely used in industry. To determine the physiologic effect of AS in the presence of hyperlipidemia, zebrafish were fed aspartame or saccharin with a high-cholesterol diet (HCD). After 12 days, 30% of zebrafish, which consumed aspartame and HCD, died with exhibiting swimming defects. The aspartame group had 65% survivability, while the control and saccharin groups had 100% survivability. Under HCD, the saccharin-fed groups had the highest increase in the serum cholesterol level (599 mg/dL). Aspartame-fed group showed a remarkable increase in serum glucose (up to 125 mg/dL), which was 58% greater than the increase in the HCD alone group. The saccharin and HCD groups had the highest cholesteryl ester transfer protein (CETP) activity (52% CE-transfer), while the HCD alone group had 42% CE-transfer. Histologic analysis revealed that the aspartame and HCD groups showed more infiltration of inflammatory cells in the brain and liver sections. Conclusively, under presence of hyperlipidemia, aspartame-fed zebrafish exhibited acute swimming defects with an increase in brain inflammation. Saccharin-fed zebrafish had an increased atherogenic serum lipid profile with elevation of CETP activity. Copyright © 2011 Elsevier Ltd. All rights reserved.

Final storage in Germany. Who is interested?

International Nuclear Information System (INIS)

Kuehn, K.

2002-01-01

The final storage of radioactive waste and spent fuel in Germany - who, in Germany, has any interest in this subject, especially now that the new Atomic Energy Act has been adopted, and who is going to read this article? The author, Professor Klaus Kuehn, examines this question, analyzing in his contribution the current situation and the points of view of those who may be interested in this topic. In Prof. Kuehn's opinion, the addresses in particular are these: - the federal government, - the opposition in the federal parliament, - the federal states, - the Federal Ministry for the Environment, - the Federal Ministry for Research, - the Federal Ministry of Economics, - the Federal Office for Radiation Protection, - the operators of nuclear power plants, - the Working Group Elaborating Procedures for Selecting Repository Sites (AkEnd). Klaus Kuehn concludes that there is little interest at the present time in the subject of Final Storage in Germany, for reasons explained in detail which result both from the political constellation and from existing constraints. (orig.) [de

AREVA Germany. International competence in nuclear technology

International Nuclear Information System (INIS)

Graeber, Ulrich

2011-01-01

AREVA NP was created in 2001 by the merger of the French nuclear technology specialist Framatome with the nuclear sector of Siemens. The company is headquartered in Paris and has regional subsidiaries in Germany and the United States. The joint venture's strength lies in its all-round competence in nuclear power plants, from reactor development to power plant services and modernization of operating plants, design and production of fuel assemblies and turn-key construction of nuclear power reactors. Major core competences are located in Germany including the test facilities which are unique in the entire group as well as electrical engineering and instrumentation and control systems. AREVA NP is part of the globally acting AREVA group which pursues a unique integrated business model. The concept covers the entire nuclear fuel cycle from uranium mining to reprocessing used fuel assemblies. At present, AREVA has 48,000 employees worldwide, of which 5,700 are Germany-based. (orig.)

Peculiarities of transformation processes in East Germany

Directory of Open Access Journals (Sweden)

Marion Dathe

2011-03-01

Full Text Available The process of socio-economic transformation of East German lands after the German reunification in 1990 is analyzed, the term "transformation" in frames of planned and market economies is defined. The author studies the historical determinants of the transformation process in Germany. German economic and industrial history in context of the driving forces and their social values, as well as the properties of the planning and economic systems that underlie the transformation of East German mentality, are considered. Further analysis is connected with economic, social and political components of the East German transformation process, "the dominance of the West", the collapse of the Council for Mutual Economic Assistance, privatization etc. Finally, the outcome of already traversed path of transformation of East Germany is considered. It is concluded, that the transformation process is not only historically conditioned situations of both the merging parties in the case of Germany, but also the positive or negative perception of its results and the motivation for its further implementation.

Prevalence of weather sensitivity in Germany and Canada

Science.gov (United States)

Mackensen, Sylvia; Hoeppe, Peter; Maarouf, Abdel; Tourigny, Pierre; Nowak, Dennis

2005-01-01

Several studies have shown that atmospheric conditions can affect well-being or disease, and that some individuals seem to be more sensitive to weather than others. Since epidemiological data on the prevalence of weather-related health effects are lacking, two representative weather sensitivity (WS) surveys were conducted independently in Germany and Canada. The objectives of this paper are: (1) to identify the prevalence of WS in Germany and Canada, (2) to describe weather-related symptoms and the corresponding weather conditions, and (3) to compare the findings in the two countries. In Germany 1,064 citizens (age >16 years) were interviewed in January 2001, and in Canada 1,506 persons (age >18 years) were interviewed in January 1994. The results showed that 19.2% of the German population thought that weather affected their health “to a strong degree,” 35.3% that weather had “some influence on their health” (sum of both = 54.5% weather sensitive), whereas the remaining 45.5% did not consider that weather had an effect on their health status. In Canada 61% of the respondents considered themselves to be sensitive to the weather. The highest prevalence of WS (high + some influence) in Germans was found in the age group older than 60 years (68%), which was almost identical in the Canadian population (69%). The highest frequencies of weather-related symptoms were reported in Germany for stormy weather (30%) and when it became colder (29%). In Canada mainly cold weather (46%), dampness (21%) and rain (20%) were considered to affect health more than other weather types. The most frequent symptoms reported in Germany were headache/migraine (61%), lethargy (47%), sleep disturbances (46%), fatigue (42%), joint pain (40%), irritation (31%), depression (27%), vertigo (26%), concentration problems (26%) and scar pain (23%). Canadian weather-sensitive persons reported colds (29%), psychological effects (28%) and painful joints, muscles or arthritis (10%). In Germany 32

The Marketisation of Guidance Services in Germany, France and Britain.

Science.gov (United States)

Rees, Teresa; Bartlett, Will; Watts, A. G.

1999-01-01

Compares developments in Britain, France, and Germany, focusing on the trends toward marketing adult career guidance services. Describes how Germany's centralized system and the quasi-market based system in France might apply in Britain. (JOW)

The DFG Viewer for Interoperability in Germany

Directory of Open Access Journals (Sweden)

Ralf Goebel

2010-02-01

Full Text Available This article deals with the DFG Viewer for Interoperability, a free and open source web-based viewer for digitised books, and assesses its relevance for interoperability in Germany. First the specific situation in Germany is described, including the important role of the Deutsche Forschungsgemeinschaft (German Research Foundation. The article then moves on to the overall concept of the viewer and its technical background. It introduces the data formats and standards used, it briefly illustrates how the viewer works and includes a few examples.

Las migraciones transnacionales en Asia Central como amenaza a la seguridad de las ex-repúblicas soviéticas (1991-2014)

OpenAIRE

Calderón Bocanegra, Camilo Alberto

2015-01-01

Esta monografía tiene como objetivo explicar cómo las migraciones transnacionales se han convertido en una amenaza para la seguridad de las ex repúblicas soviéticas de Asia central durante las últimas dos décadas dando lugar a un Complejo de Seguridad Regional (CSR). Mediante la teoría crítica del CSR elaborada por Barry Buzan, se buscará probar que estos flujos migratorios transnacionales han configurado una amenaza compartida para la seguridad de la región debido a su asociación con grupos ...

Evaluación de la formación permanente del profesorado en la República Dominicana : el caso del Infocam

OpenAIRE

Ayala de la Cruz, María Esperanza

2016-01-01

El presente estudio estuvo orientado a describir y valorar la calidad del sistema de formación, relacionándolo con la aplicación de las políticas educativas y de formación permanente o continua del profesorado en la República Dominicana. Su conexión con las necesidades e intereses de los docentes, su incidencia en el desarrollo personal, profesional, y de desempeño. Teniendo como intención estratégica generar y aportar líneas para avanzar hacia un sistema de evaluación de la formación...

La disolución de la Asamblea Nacional como facultad del Presidente de la República: análisis comparativo

OpenAIRE

Torres Rosero, Galo Ramiro

2016-01-01

La Constitución del Ecuador 2008 incorporó una nueva figura jurídica denominada “la disolución de la Asamblea Nacional como facultad del Presidente de la República”. Esta institución es novísima en nuestro ordenamiento jurídico y, de acuerdo a los constituyentes de Montecristi, ha sido insertada en nuestra legislación con el propósito de garantizar el equilibrio de poderes entre las funciones del Estado. El objetivo de este trabajo es conocer a profundidad esta figura, que tuvo su origen en E...

Engineering testing requirements in FED/INTOR

International Nuclear Information System (INIS)

Abdou, M.A.; Nygren, R.E.; Morgan, G.D.; Trachsel, C.A.; Wire, G.; Oppermann, E.; Puigh, R.; Gold, R.E.

1982-10-01

The FED/INTOR critical issues activity has addressed three key testing requirements that have the largest impact on the design, operation and cost of FED/INTOR. These are: (1) the total testing time (fluence) during the device lifetime, (2) the minimum number of back-to-back cycles, and (3) the neutron wall load (power density in the first wall/blanket). The testing program activities were structured into three tasks in order to define the benefits, and in some cases, costs and risks of these testing requirements. The three tasks were carried out with wide participation of experts from a number of organizations in the United States. Similar effort was performed by Japan, the European Community and the Soviet Union

The costs of coexistence on farms in Germany

DEFF Research Database (Denmark)

Punt, Maarten J.; Venus, Thomas J.; Wesseler, Justus H H

2017-01-01

for farmers in their cultivation decisions, and therefore it is important to measure these costs. In this article, we investigate the costs of different coexistence measures for farmers in Germany. Currently, GM crop cultivation is outlawed in Germany, but there was a short period from 2005-2008 when...... that there are important differences in farm characteristics and overall landscape configuration that influence the costs or burden of coexistence measures....

Germany's Armed Forces in the Second World War: Manpower, Armaments, and Supply.

Science.gov (United States)

Balsamo, Larry T.

1991-01-01

Discusses the state of Germany's armed forces in World War II. Describes Germany's progress from inferior weaponry and unprepared military at the beginning of the war to superior weapons and fighting. Stresses heavy German dependence on horse drawn supply. Credits Germany's defeat to human attrition accelerated by Hitler's operational leadership.…

Football business models: Why did Germany win the World Cup?

DEFF Research Database (Denmark)

Cortsen, Kenneth

2016-01-01

This article looks into the managerial aspects related to why and how Germany won the 2014 FIFA World Cup.......This article looks into the managerial aspects related to why and how Germany won the 2014 FIFA World Cup....

[Pharmacological aspects of pain research in Germany].

Science.gov (United States)

Niederberger, E; Kuner, R; Geißlinger, G

2015-10-01

In spite of several approved analgesics, the therapy of pain still constitutes a challenge due to the fact that the drugs do not exert sufficient efficacy or are associated with severe side effects. Therefore, the development of new and improved painkillers is still of great importance. A number of highly qualified scientists in Germany are investigating signal transduction pathways in pain, effectivity of new drugs and the so far incompletely investigated mechanisms of well-known analgesics in preclinical and clinical studies. The highlights of pharmacological pain research in Germany are summarized in this article.

Germany: energy transition or revolution

International Nuclear Information System (INIS)

Boulanger, V.

2013-01-01

Germany has decided to phase out nuclear power by 2022 but it wants also to get rid of fossil energies by 2050. Those ambitious goals imply to be able to cut by half the demand for primary energy by 2050 which will be only possible if the need for building heating is cut by 80%, the constraint on transport is less important: one million of electrical vehicles will have to be on the road by 2020 and 3 millions 10 years later. In 2012 the production of electricity was made mainly from coal (44.7%), renewable energies (21.9%), nuclear energy (16%), natural gas (11.3%) and other energies (fuel...) (6.1%). Today the renewable energy sector is a major industrial sector in Germany, it represents about 382000 jobs directly or indirectly, it means more than the sector of conventional energies. (A.C.)

Acidification policy - control of acidifying emissions in Germany

International Nuclear Information System (INIS)

Schaerer, B.

1992-01-01

Since the mid-eighties total annual acidifying emissions have started to decline in West Germany. There was considerable impact on this positive trend in air pollution by the control of SO 2 and NO x emissions from large boilers, which were reduced by more than 80%. Corresponding control programmes have been established for other groups of sources as well as other pollutants and - with unification - for East Germany. The driving force behind this development was and still is first of all the legal principle of anticipatory action or precaution which means in practical terms 'emission minimization'. This cornerstone of German clean air legislation is the most powerful components of Germany's 'acidification policy', as it requires policy-makers to draw up new or review existing regulations for emission reduction based on requirements according to the state of the art and forces operators to apply the most modern ways and means of operation. This paper describes the system used in Germany to deal with air pollution, the emission minimization strategy, and the actions against acidifying emissions based thereon. In addition, an outlook on what might be necessary to cope with the challenges of a sustainable development concerning acidification is given. 1 ref., 1 fig., 2 tabs

Climatic change in Germany. Development, consequences, risks and perspectives

International Nuclear Information System (INIS)

Brasseur, Guy; Jacob, Daniela; Schuck-Zoeller, Susanne

2017-01-01

The book on the climatic change in Germany includes contributions to the following issues: global climate projections and regional projections in Germany and Europe: observation of the climatic change in Central Europe, regional climate modeling, limits and challenges of the regional climate modeling; climatic change in Germany - regional features and extremes: temperature and heat waves, precipitation, wind and cyclones, sea-level increase, tides, storm floods and sea state, floods, definition uncertainties, draughts, forest fires, natural risks; consequences of the climatic change in Germany: air quality, health, biodiversity, water resources, biochemical cycles, agriculture, forestry, soils, personal and commercial transport, cities and urban regions, tourism, infrastructure, energy and water supplies, cost of the climatic change and economic consequences; overall risks and uncertainties: assessment of vulnerabilities, literature review, climatic change as risk enhancement in complex systems, overall risks and uncertainties, decision making under uncertainties in complex systems; integrated strategies for the adaptation to the climatic change: the climate resilient society - transformations and system changes, adaptation to the climatic change as new political field, options for adaptation strategies.

Evolving Microbial Communities in Cellulose-Fed Microbial Fuel Cell

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Renata Toczyłowska-Mamińska

2018-01-01

Full Text Available The abundance of cellulosic wastes make them attractive source of energy for producing electricity in microbial fuel cells (MFCs. However, electricity production from cellulose requires obligate anaerobes that can degrade cellulose and transfer electrons to the electrode (exoelectrogens, and thus most previous MFC studies have been conducted using two-chamber systems to avoid oxygen contamination of the anode. Single-chamber, air-cathode MFCs typically produce higher power densities than aqueous catholyte MFCs and avoid energy input for the cathodic reaction. To better understand the bacterial communities that evolve in single-chamber air-cathode MFCs fed cellulose, we examined the changes in the bacterial consortium in an MFC fed cellulose over time. The most predominant bacteria shown to be capable electron generation was Firmicutes, with the fermenters decomposing cellulose Bacteroidetes. The main genera developed after extended operation of the cellulose-fed MFC were cellulolytic strains, fermenters and electrogens that included: Parabacteroides, Proteiniphilum, Catonella and Clostridium. These results demonstrate that different communities evolve in air-cathode MFCs fed cellulose than the previous two-chamber reactors.

Feeding behavior in lambs fed diets containing crambe cake

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Mirna Adriane Syperreck

2016-09-01

Full Text Available It was evaluated the feeding behavior of lambs fed diets containing 30% sorghum silage and 70% crambe cake (30:70 diet, and 70% sorghum silage and 30% crambe cake (70:30 diet under voluntary and controlled consumption. The experimental design used was a 4 × 4 Latin square, with four animals, four periods, and four treatments; feeding behavior was determined by observation. The results indicated that animals fed the 30:70 diet showed higher DM and NDF (g day-1 than those fed the 70:30 diet. Animals fed the 70:30 diet showed longer feeding times (h kg-1 DM, mastication (min kg-1 DM and min kg-1 NDF, rumination (min day-1 and min kg-1 DM, and the largest number of mericics chewing per bolus; however, a higher feed efficiency (g DM h-1 was observed in the 30:70 diet group. Furthermore, animals feeding voluntarily had higher DM intake and chewed for longer. Therefore, the combined results indicated that crambe cake could be used in the diet of sheep without affecting feeding behavior.

The photovoltaic sector in Germany, where does it go?

International Nuclear Information System (INIS)

Anon.

2012-01-01

Opinion polls show that photovoltaic power is very popular in Germany. This sector employs about 130.000 people and although a lot of solar modules are imported from China, other components like current inverters are fabricated in Germany and as a whole the trade balance is positive and the export rate nears 50%. In 2011 Germany invested 25 billion euros in the photovoltaic sector and now about 5% of the consumed electricity is photovoltaic power. Photovoltaic power reached grid parity in february 2012 for some consumers and the German government decided to reduce the purchase tariff drastically which may jeopardize the aim of having a photovoltaic park of 51 GWc by 2020. (A.C.)

Growth Performance and Hematological Traits of Weaner Pigs Fed ...

African Journals Online (AJOL)

Sixty Weaner pigs with an average initial live weight of 6.81 ± 1.0kg were studied for their growth and haematological parameters when fed graded levels of raw bambara waste (BW) using a completely randomized design (CRD). They were fed five diets containing 0, 25, 50, 75 and 100 percentage composition for 5 months ...

Are Dogs That Are Fed from a Raised Bowl at an Increased Risk of Gastric Dilation Volvulus Compared with Floor-Fed Dogs?

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Louise Anne Buckley

2017-01-01

Full Text Available There are only two studies that study the effect of raised feeders on the risk of Gastric Dilatation Volvulus (GDV and their findings conflict. Only one study found a significant effect of feeder height, with large and giant breeds fed from a raised feeder being at an increased risk of GDV floor fed dogs. However, these authors found that, where the feeder was raised, the height of the feeder that increased the GDV risk was affected by the size of the dog. Large breed dogs were more likely to develop a GDV if fed from a bowl ≤ 1 foot tall, whereas giant breed dogs were more likely to develop a GDV if fed from a bowl > 1 foot tall. No studies found that feeding from a raised feeder reduced the risk of GDV relative to feeding from the floor. Therefore, the safest option in the absence of further evidence is to advise that owners of ‘at risk’ dogs feed from a feeder on the floor. This may not reduce the risk of GDV, but there is no evidence to suggest that it will increase the risk. 

Energy R and D in Germany

Energy Technology Data Exchange (ETDEWEB)

Runci, PJ

1999-11-01

Germany's total national (i.e., combined public and private sector) funding for R&D stood at $42 billion in 1997. The private sector accounted for nearly 62% ($24 billion) of the total, while the public sector accounted for approximately 38%. Since the late 1970s, when the public and private sectors each funded roughly half of Germany's R&D, the private sector has steadily assumed a larger and larger role as the dominant supporter of R&D activity, while overall government funding has remained essentially flat for much of the past two decades. In addition to declining relative to private R&D expenditures, public R&D expenditures in Germany declined by 4% in real terms between 1991 and 1997, to approximately $15 billion. The reduction in R&D investments in the public sector can be attributed in large part to the financial challenges associated with German reunification and related shifts in social priorities including efforts to address high unemployment and to rebuild basic infrastructure in the eastern states. R&D expenditures have also declined as a percentage of the total public budget, from a peak of 3.4% in 1985 to 2.7% in 1996. Energy R&D has been the hardest hit of all major socioeconomic areas of R&D expenditure funded by the German government. Between 1981 and 1997, public energy R&D fell from approximately $1.6 billion to $400 million--a 75% real decline. The $850 million reduction in Germany's fission R&D budget (which constituted two-thirds of government R&D investment in 1985) explains some 90% of the funding decline. Negative public perceptions regarding the safety and environmental impacts of nuclear energy have reduced nuclear power's viability as a long-term energy option for Germany. Discussions of a complete nuclear phaseout are now under way. At the same time, the German government has slashed its investments in fossil energy R&D by more than 90%. While energy efficiency and renewable energy technologies have fared relatively well in comparison

Phenotypical analysis of the Lactobacillus rhamnosus GG fimbrial spaFED operon: surface expression and functional characterization of recombinant SpaFED pili in Lactococcus lactis.

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Johanna Rintahaka

Full Text Available A noticeable genomic feature of many piliated Gram-positive bacterial species is the presence of more than one pilus-encoding operon. Paradigmatically, the gut-adapted Lactobacillus rhamnosus GG strain contains two different fimbrial operons in its genome. However, whereas one of these operons (called spaCBA is encoding for the functionally mucus-/collagen-binding SpaCBA pilus, for the other operon (called spaFED any native expression of the SpaFED-called pili is still the subject of some uncertainty. Irrespective of such considerations, we decided it would be of relevance or interest to decipher the gross structure of this pilus type, and as well assess its functional capabilities for cellular adhesion and immunostimulation. For this, and by following the approach we had used previously to explicate the immuno-properties of SpaCBA pili, we constructed nisin-inducible expression clones producing either wild-type or SpaF pilin-deleted surface-assembled L. rhamnosus GG SpaFED pili on Lactococcus lactis cells. Using these piliated lactococcal constructs, we found that the pilin-polymerized architecture of a recombinant-produced SpaFED pilus coincides with sequence-based functional predictions of the related pilins, and in fact is prototypical of those other sortase-dependent pilus-like structures thus far characterized for piliated Gram-positive bacteria. Moreover, we confirmed that among the different pilin subunits encompassing spaFED operon-encoded pili, the SpaF pilin is a main adhesion determinant, and when present in the assembled structure can mediate pilus binding to mucus, certain extracellular matrix proteins, and different gut epithelial cell lines. However, somewhat unexpectedly, when recombinant SpaFED pili are surface-attached, we found that they could not potentiate the existing lactococcal cell-induced immune responses so elicited from intestinal- and immune-related cells, but rather instead, they could dampen them. Accordingly, we

Phenotypical analysis of the Lactobacillus rhamnosus GG fimbrial spaFED operon: surface expression and functional characterization of recombinant SpaFED pili in Lactococcus lactis.

Science.gov (United States)

Rintahaka, Johanna; Yu, Xia; Kant, Ravi; Palva, Airi; von Ossowski, Ingemar

2014-01-01

A noticeable genomic feature of many piliated Gram-positive bacterial species is the presence of more than one pilus-encoding operon. Paradigmatically, the gut-adapted Lactobacillus rhamnosus GG strain contains two different fimbrial operons in its genome. However, whereas one of these operons (called spaCBA) is encoding for the functionally mucus-/collagen-binding SpaCBA pilus, for the other operon (called spaFED) any native expression of the SpaFED-called pili is still the subject of some uncertainty. Irrespective of such considerations, we decided it would be of relevance or interest to decipher the gross structure of this pilus type, and as well assess its functional capabilities for cellular adhesion and immunostimulation. For this, and by following the approach we had used previously to explicate the immuno-properties of SpaCBA pili, we constructed nisin-inducible expression clones producing either wild-type or SpaF pilin-deleted surface-assembled L. rhamnosus GG SpaFED pili on Lactococcus lactis cells. Using these piliated lactococcal constructs, we found that the pilin-polymerized architecture of a recombinant-produced SpaFED pilus coincides with sequence-based functional predictions of the related pilins, and in fact is prototypical of those other sortase-dependent pilus-like structures thus far characterized for piliated Gram-positive bacteria. Moreover, we confirmed that among the different pilin subunits encompassing spaFED operon-encoded pili, the SpaF pilin is a main adhesion determinant, and when present in the assembled structure can mediate pilus binding to mucus, certain extracellular matrix proteins, and different gut epithelial cell lines. However, somewhat unexpectedly, when recombinant SpaFED pili are surface-attached, we found that they could not potentiate the existing lactococcal cell-induced immune responses so elicited from intestinal- and immune-related cells, but rather instead, they could dampen them. Accordingly, we have now provided

Bioavailability of lead in rats fed human diets

International Nuclear Information System (INIS)

Kostial, K.; Kello, D.

1979-01-01

The bioavailability of lead was studied in rats fed various baby foods (Babymix-turkey, Babymix-vegetables, Frutolino-fruit, Frutamix-bananas, Babyron-S-26, Truefood), cow's milk, bread, liver and standard rat diet. Lead absorption was determined by measuring the whole body retention of 203 Pb 6 days after a single oral application. Highest absorption values ranging from 17 to 20% were obtained in animals fed cow's milk and fruit foods. Rats on other human diets absorbed between 3 and 8% of the radioactive lead dose. Only in animals on rat diet lead absorption was below 1%. It is concluded that rats fed human diets show absorption values similar to those in humans. This might indicate that the bioavailability of lead is primarily dependent on dietary habits. This experimental model, if confirmed by further work, might be useful for obtaining preliminary data on the bioavailability of metals from various foods

República, nación y democracia ante el desafío de la diversidad Republic, nation and democracy against the challenge of diversity

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Susana Villavicencio

2010-12-01

Full Text Available La República no es sólo el nombre de una nación estado y su régimen. Es también un modelo nacional de integración basado en la concepción universalista de la ciudadanía que afirma la figura abstracta de la persona jurídica, portadora de iguales derechos y obligaciones, y valores de civismo y civilidad. Este trabajo analiza cómo la emergencia de la diversidad cultural en Argentina pone en cuestión los conceptos modernos de república, nación y democracia. Examina asimismo cómo los legados de la república, que supone una visión homogeneizada de la diversidad, implican una ambivalencia entre la adhesión a principios universalistas de progreso de la humanidad y la realidad de una democracia excluyente que valorizaba una cultura por sobre otras. Se estudian las narrativas de la identidad nacional, mostrando cómo la oposición civilización -barbarie afecta la visión de los desafíos del futuro de la democracia en América Latina.Republic is not only the name of a nation and its regime. It is also a national model of integration based on a universalist conception of citizenship that sustains the abstract figure of the legal person, endowed with equal rights and obligations, and values of civism and civility, the foundation stones of a society that arises from a contract. This paper analyses how the emergency of the cultural diversity in Argentina calls into question modern political concepts like republic, nation and democracy. It is also evaluated how the republic's inheritance, which supposes an homogenized sight of diversity, gives rise to an ambivalence among the adherence to universalist principles of the progress of humanity and the reality of an excluding democracy that gave value to one culture above others. The narratives of national identity are studied describing how the opposition between civilization and barbariy affects the way Latin Americans see the great challenges presented by the future of democracy, and by the

Regional cost differences of hospital supply in Germany

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Lauterbach, Karl W.

2005-04-01

Full Text Available The intended adoption of a global reimbursement system for inpatient care in Germany envisions identical payments for identical treatments at different hospitals. This may lead to losses in some hospitals and may cause problems for the supply with health care facilities in the long run if there a important regional cost differences. Cost and performance data of 1112 hospitals in Germany have been analysed for regional differences in 2001: As regional categorizations we used official classification schemes based on centrality. The investigation does not support the postulation of additional payments for selected regions in Germany accounting for level cost-differences between hospitals. Confounding influence factors like ownership and hospital size seem to be more important. We recommend further investigations to evaluate regional cost-differences on the level of medical wards and using more risk-adjusted data. The examination of the individual case is necessary.

Mutagenicity assayed by dominant lethality testing in mice fed a combined gamma-irradiated diet

International Nuclear Information System (INIS)

Rupova, I.; Katsarova, Ts.; Bajrakova, A.; Baev, I.; Tencheva, S.

1980-01-01

Mice fed a combined gamma-irradiated diet were examined for a mutagenic effect using the dominant lethality test. Their feed contained the following irradiated ingredients: 20% maize, 10% dried plums, and 5% walnut kernels. Taking into account cycle duration in spermatogenesis and oogenesis, males were fed this special diet throughout 56 days, and females throughout 21 days. The experiments involved three animal groups: (1) fed the special diet containing irradiated ingredients; (2) fed the special diet but with the ingredients nonirradiated; and (3) fed standard vivarium diet. Matings to provide the first generation were between one parent fed the special diet and a partner fed standard diet. With an adequate number of implants examined on day 16 of gestation, embryonic death rate was not found to be increased; hence, induction of dominant lethality from consumption of irradiated diet failed to be demonstrated

Seminar on Biogas in France and in Germany: Regulatory framework, potentials and challenges

International Nuclear Information System (INIS)

Abadie, Pierre-Marie; Boettcher, Katharina; Stolpp, Sebastian; Vincent, Eric; Chapron, Thibaut; Schuette, Andreas; Paquin, Laurent; Ingremeau, Claire; Moeller, Kurt; Trommler, Marcus; Denysenko, Velina; Bosso, Valerie

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a Seminar on biogas in France and Germany. In the framework of this French-German exchange of experience, about 120 participants exchanged views on the legal framework, the characteristics of this industry, and the opportunities and technical challenges of biogas use in both countries. Differences and similarities were noticed in both countries, for instance regarding the use of energy cultures and digestates. This document brings together the available presentations (slides) made during this event: 1 - The French biogas in the perspective of 2020 (Pierre-Marie Abadie); 2 - Biogas Opportunities in Germany - Status January 2014 (Katharina Boettcher); 3 - Biogas market in Germany (Sebastian Stolpp); 4 - Biogas in France and Germany, Current status and development outlooks in France (Eric Vincent); 5 - Biogas use in France and Germany - a comparison (Thibaut Chapron); 6 - Alternatives to the use of maize in biogas plants - Current research results from Germany (Andreas Schuette); 7 - Inter-crops in France: analysis of the potentials (Laurent Paquin); 8 - Digestates management in France, legislative and technical advances (Claire Ingremeau); 9 - The management of digestates in Germany: Fertilizer application and status of the art (Kurt Moeller); 10 - Status quo of Biomethane in Germany - Development, Technology and Costs (Marcus Trommler); 11 - GrDF's views and actions on biogas. Biomethane injection in France: state-of-the-art and first status (Valerie Bosso)

Claw lesions and lameness in zero-grazed cattle fed on brewer\\'s ...

African Journals Online (AJOL)

Feet from 218 cattle in 35 zerograzing units were studied from June 2003 to June 2004. Cattle in 20 of the zero-grazing units were fed brewer's grain while 15 of the units did not feed brewer's grain. The units were conveniently selected. Comparing brewer's grain fed and non-grain fed animals, the prevalence of laminitis ...

Uma ditadura contra a república: política econômica e poder político em Roberto Campos

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Ricardo V. Silva

2006-11-01

Full Text Available O artigo examina o pensamento político de Roberto Campos entre meados das décadas de 1950 e 1970. Neste período, além de importantes funções governamentais, Campos dedicou-se intensamente à luta de idéias, publicando grande quantidade de artigos e ensaios. Será desenvolvida a hipótese de que o seu pensamento político aponta para a institucionalização de um sistema político de tipo autoritário como o mais adequado às condições culturais e políticas da sociedade brasileira. A principal característica deste tipo de sistema consiste na hipertrofia do poder Executivo estatal, sob comando de militares e tecnocratas, relativamente aos demais poderes da República. A função primordial do poder Executivo hipertrofiado são a elaboração e a implementação de reformas institucionais e de políticas econômicas "racionais", contra as resistências pretensamente particularistas e irracionais dos diferentes setores da sociedade brasileira. Essa hipótese colide frontalmente com a sugestão de Campos de que o regime instituído após o movimento de 1964 seria uma espécie de atualização, nas condições da sociedade brasileira de então, do instituto da "ditadura comissária" da antiga República romana, pelo qual se permitia a eleição de um ditador por um curto período de tempo para debelar eventuais ameaças às instituições republicanas.

Modernidade republicana e diocesanização do catolicismo no Brasil: as relações entre Estado e Igreja na Primeira República (1889-1930

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Maurício de Aquino

2012-01-01

Full Text Available Partindo da análise de documentação consultada em arquivos do Brasil e do Vaticano, o artigo discute as relações entre Estado e Igreja Católica Apostólica Romana (ICAR no período da Primeira República brasileira. Considera-se que a Proclamação da República em 15 de novembro de 1889 foi associada, por algumas parcelas das elites brasileiras da época, ao ideário do progresso e da civilização, sendo uma de suas primeiras tarefas a extinção do padroado em 7 de janeiro de 1890. O laicismo determinado nessa ocasião pelo Decreto 119-A revelou-se, entretanto, ambíguo e pragmático. Livre das amarras constitucionais do padroado, o Estado criou um novo campo de relações com as diferentes confissões religiosas, segundo os seus próprios interesses institucionais. Nesse contexto, a ICAR, por sua vez, empreendeu um processo de reforma e reorganização eclesiástica cujo fulcro consistiu na criação de dioceses e jurisdições similares - um amplo e complexo processo territorial, político e discursivo ao qual se pode denominar diocesanização.

Conventional Morphology Versus PCR Sequencing, rep-PCR, and MALDI-TOF-MS for Identification of Clinical Aspergillus Isolates Collected Over a 2-Year Period in a University Hospital at Kayseri, Turkey.

Science.gov (United States)

Atalay, Altay; Koc, Ayse Nedret; Suel, Ahmet; Sav, Hafize; Demir, Gonca; Elmali, Ferhan; Cakir, Nuri; Seyedmousavi, Seyedmojtaba

2016-09-01

Aspergillus species cause a wide range of diseases in humans, including allergies, localized infections, or fatal disseminated diseases. Rapid detection and identification of Aspergillus spp. facilitate effective patient management. In the current study we compared conventional morphological methods with PCR sequencing, rep-PCR, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) for the identification of Aspergillus strains. A total of 24 consecutive clinical isolates of Aspergillus were collected during 2012-2014. Conventional morphology and rep-PCR were performed in our Mycology Laboratory. The identification, evaluation, and reporting of strains using MALDI-TOF-MS were performed by BioMérieux Diagnostic, Inc. in Istanbul. DNA sequence analysis of the clinical isolates was performed by the BMLabosis laboratory in Ankara. Samples consisted of 18 (75%) lower respiratory tract specimens, 3 otomycosis (12.5%) ear tissues, 1 sample from keratitis, and 1 sample from a cutaneous wound. According to DNA sequence analysis, 12 (50%) specimens were identified as A. fumigatus, 8 (33.3%) as A. flavus, 3 (12.5%) as A. niger, and 1 (4.2%) as A. terreus. Statistically, there was good agreement between the conventional morphology and rep-PCR and MALDI-TOF methods; kappa values were κ = 0.869, 0.871, and 0.916, respectively (P < 0.001). The good level of agreement between the methods included in the present study and sequence method could be due to the identification of Aspergillus strains that were commonly encountered. Therefore, it was concluded that studies conducted with a higher number of isolates, which include other Aspergillus strains, are required. © 2016 Wiley Periodicals, Inc.

HTGR type reactors in West Germany. Realizations and prospects

International Nuclear Information System (INIS)

Dauenert, U.

1978-01-01

The framework within which the research studies on high temperature reactors have been pursued in West Germany since 1960 is recalled. The principles guiding the present policy of the country in this domain are given: choice of a single technical conception that be applied both to reactors generating electricity and reactors producing high temperature heat for industrial processes such as coal gasification; to group the technical and industrial potentials of West Germany in this domain; financial and technical participation of electricity producers in the expected realizations; international cooperation. In this technique, West Germany is at present among the most advanced nations with the realization of a prototype 300 MWe reactor, financed by the electricity producers and a contribution of government [fr

Radioactive waste in Federal Germany

International Nuclear Information System (INIS)

Brennecke, P.; Schumacher, J.; Warnecke, E.

1988-01-01

The Physikalisch-Technische Bundesanstalt (PTB) is responsible for the long-term storage and disposal of radioactive waste according to the Federal Atomic Energy Act. On behalf of the Federal Minister of the Environment, Nature Conservation and Nuclear Safety, since 1985, the PTB has been carrying out annual inquiries into the amounts of radioactive waste produced in the Federal Republic of Germany. Within the scope of this inquiry performed for the preceding year, the amounts of unconditioned and conditioned waste are compiled on a producer- and plant-specific basis. On the basis of the inquiry for 1986 and of data presented to the PTB by the waste producers, future amounts of radioactive waste have been estimated up to the year 2000. The result of this forecast is presented. In the Federal Republic of Germany two sites are under consideration for disposal of radioactive waste. In the abandoned Konrad iron mine in Salzgitter-Bleckenstedt it is intended to dispose of such radioactive waste which has a negligible thermal influence upon the host rock. The Gorleben salt dome is being investigated for its suitability for the disposal of all kinds of solid and solidified radioactive wastes, especially of heat-generating waste. Comparing the estimated amount of radioactive wastes with the capacity of both repositories it may be concluded that the Konrad and Gorleben repositories will provide sufficient capacity to ensure the disposal of all kinds of radioactive waste on a long-term basis in the Federal Republic of Germany. 1 fig., 2 tabs

Germany versus the United States: Monetary Dominance in the Eurozone

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Chee-Heong Quah

2016-04-01

Full Text Available This study inspects if there is greater convergence with Germany amongst the Eurozone founding members and if their relations with the hegemonic economy have been more symmetrical after “euroization”. The dimensions explored are those inspired by the optimum currency areas (OCA framework. To some extent, the findings could signify if real convergence has been significantly endogenous. At the same time, to assess the relative dominance of Germany, the features against Germany are compared to those against US. In addition, the paper also appraises some aspects of economic performance to check whether economic conditions across the states have improved and converged after unification. In some convergence aspects, findings suggest remarkable convergence with Germany and across the states but also relative convergence with US. On economic performance, results indicate substantial improvements in inflation and unemployment. Amongst the founding states, Ireland has idiosyncratically shown serious divergences in a number of the convergence and performance measures.

76 FR 11509 - Brass Sheet and Strip From France, Germany, Italy, and Japan

Science.gov (United States)

2011-03-02

...)] Brass Sheet and Strip From France, Germany, Italy, and Japan AGENCY: United States International Trade... and strip from France, Germany, Italy, and Japan. SUMMARY: The Commission hereby gives notice that it... France, Germany, Italy, and Japan would be likely to lead to continuation or recurrence of material...

Homonota fasciata Duméril y Bibron, 1839 (Reptilia, Squamata, Phyllodactylidae. Primer registro para la provincia de Corrientes (República Argentina

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Falcione, Camila

2011-05-01

Full Text Available Homonota fasciata Duméril & Bibron, 1839. República Argentina, Provincia de Corrientes, Departamento Bella Vista, Cuarta Sección, Colonia Progreso, Loma Sur, Toropí (28°35'55" S; 59°03'38" W (Figura 1. Colectores: Eduardo Etchepare, María del Rosario Ingaramo, Camila Falcione y Roberto Aguirre. 05 de abril de 2011. Se colectaron 4 ejemplares adultos (2 machos y 2 hembras y 1 juvenil, depositados en la Colección Herpetológica de la Universidad Nacional del Nordeste (UNNEC-11212, UNNEC-11213, UNNEC- 11214, UNNEC-11215 y UNNEC-11216.

Homozygous familial hypercholesterolemia (HoFH in Germany: an epidemiological survey

Directory of Open Access Journals (Sweden)

Walzer S

2013-05-01

Full Text Available S Walzer,1 K Travers,2 S Rieder,3 E Erazo-Fischer,3 D Matusiewicz41MArS Market Access and Pricing Strategy UG (hb, Weil am Rhein, Germany; 2United Biosource Corporation, Lexington, USA; 3Alcimed GmbH, Cologne, Germany; 4Institute for Health Care Management and Research, Faculty of Economics and Business Administration, University of Duisburg-Essen, Essen, GermanyIntroduction: In Europe a disease is recognized as rare if less than 1 in 2000 people suffer from the specific disease. In patients with familial homozygous hypercholesterolemia (HoFH the accumulation of low-density lipoprotein cholesterol (LDL-C leads to generalized atherosclerosis due to an insufficient functioning of the LDL-C receptors. Patients die early sometimes even in the mid-30s, from myocardial infarction or stroke. For the German population, insufficient epidemiological evidence exists.Methods: A systematic literature search in EMBASE and Medline was performed in conjunction with a targeted manual search for epidemiological HoFH studies. Additionally a nationwide survey was conducted in Germany in all identified apheresis- and lipid centers. The purpose of the survey was the validation of the systematic literature search results based on empirical (practice data.Results: In total 961 publications were found, 874 were excluded based on pre-defined exclusion criteria leaving only 87 for further review. After review of the identified abstracts (n = 87 23 publications were identified as epidemiological studies. Only one publication was found which reported a prevalence of 1:1,000,000. The qualitative survey among 187 physicians in Germany also revealed a low prevalence: 95 HoFH patients were identified in 35 centers.Conclusion: The estimated frequency of homozygous familial hypercholesterolemia patients in Germany is around 95 (1:860,000 and the disease should be recognized as rare according to the definition of the European Medical Agency.Keywords: epidemiology, homozygous

Physical and sensory characterization and consumer preference of corn and barley-fed beef.

Science.gov (United States)

Wismer, W V; Okine, E K; Stein, A; Seibel, M R; Goonewardene, L A

2008-11-01

Steaks from corn-fed and barley-fed beef were characterized by a trained panel, which rated corn-fed beef higher (pconsumers preferred (pconsumers showed no preference (p>0.05) for either type of finished beef. Japanese consumers showed a preference (ppreference for cooked corn-fed steaks (p0.05) were observed for Warner-Bratzler shear, marbling scores, cooking losses or Hunter colorimeter values. There was a trend for higher concentrations (p0.10) in mono or polyunsaturated fatty acids.

Problems of Economic Development in Reunified Germany. Retrospective Approach

Directory of Open Access Journals (Sweden)

Marta Gotz

2011-07-01

Full Text Available Does Eastern Germany differ significantly from Western part in economic terms? How have new Bundeslnder been developing over past twenty years? How fast has East been catching up with West? What could have hampered convergence? How today are German states equipped with factors determining future growth? How the new Bundeslnder performed do compared with the old ones? This paper seeks to address above mentioned questions. It offers a comprehensive review of key economic developments of two decades of reunited Germany. Particularly it examines current economic landscape; investigates convergence processes taking place since reunification and tries to identify most likely impediments hampering full catching up. Finally, it aims at assessing contemporary growth potential of German states. With respect to the starting point poor performance of East Germany back in 1990 the progress made and results achieved are impressive. Though, comparing the situation with Western part of the country significant discrepancies continue to exist. Certainly, assessment of the last twenty years of reunited Germany hinges much upon perspective taken. Two decades after Berlin Wall Fall opinions on economic consequences of reunification are more balanced, since much has been achieved, but much still needs to be done.

Direct fed microbial supplementation repartitions host energy to the immune system.

Science.gov (United States)

Qiu, R; Croom, J; Ali, R A; Ballou, A L; Smith, C D; Ashwell, C M; Hassan, H M; Chiang, C-C; Koci, M D

2012-08-01

Direct fed microbials and probiotics are used to promote health in livestock and poultry; however, their mechanism of action is still poorly understood. We previously reported that direct fed microbial supplementation in young broilers reduced ileal respiration without changing whole-body energy expenditure. The current studies were conducted to further investigate the effects of a direct fed microbial on energy metabolism in different tissues of broilers. One hundred ninety-two 1-d-old broiler chicks (16 chicks/pen) were randomly assigned to 2 dietary groups: standard control starter diet (CSD) and CSD plus direct fed microbial (DFMD; 0.3%) with 6 pens/treatment. Body weight, feed consumption, whole-body energy expenditure, organ mass, tissue respiration rates, and peripheral blood mononuclear cell (PBMC) ATP concentrations were measured to estimate changes in energy metabolism. No differences in whole body energy expenditure or BW gain were observed; however, decreased ileal O(2) respiration (P energy consumption by PBMC corresponded with an altered immune response, broilers were immunized with sheep red blood cells (SRBC) and assayed for differences in their humoral response. The DFMD-fed broilers had a faster rate of antigen specific IgG production (P direct fed microbial used in this study resulted in energy re-partitioning to the immune system and an increase in antibody production independent of changes in whole body metabolism or growth performance.

Tratado de amistad, comercio y navegación entre la República de Colombia su Majestad el Rey del Reyno Unido de la Gran Bretaña e Irlanda en el nombre de la Santísima Trinidad

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Alvaro Acevedo Acevedo

2013-10-01

Full Text Available Habiéndose establecido estensas relaciones comerciales por una serie de años, entre varias provincias, ó países de América, que unidos ahora constituyen la República de Colombia, y los dominios de su Majestad el Rey del Reino Unido de la Gran Bretaña, é Irlanda, ha parecido conveniente, así para la seguridad y fomento de aquella correspondencia comercial, como para mantener la buena inteligencia entre su dicha Majestad, y la dicha República, que las relaciones que ahora subsisten entre ambas, sean regularmente conocidas y confirmadas por medio de un tratado de amistad, comercio y navegación.

BioFed: federated query processing over life sciences linked open data.

Science.gov (United States)

Hasnain, Ali; Mehmood, Qaiser; Sana E Zainab, Syeda; Saleem, Muhammad; Warren, Claude; Zehra, Durre; Decker, Stefan; Rebholz-Schuhmann, Dietrich

2017-03-15

Biomedical data, e.g. from knowledge bases and ontologies, is increasingly made available following open linked data principles, at best as RDF triple data. This is a necessary step towards unified access to biological data sets, but this still requires solutions to query multiple endpoints for their heterogeneous data to eventually retrieve all the meaningful information. Suggested solutions are based on query federation approaches, which require the submission of SPARQL queries to endpoints. Due to the size and complexity of available data, these solutions have to be optimised for efficient retrieval times and for users in life sciences research. Last but not least, over time, the reliability of data resources in terms of access and quality have to be monitored. Our solution (BioFed) federates data over 130 SPARQL endpoints in life sciences and tailors query submission according to the provenance information. BioFed has been evaluated against the state of the art solution FedX and forms an important benchmark for the life science domain. The efficient cataloguing approach of the federated query processing system 'BioFed', the triple pattern wise source selection and the semantic source normalisation forms the core to our solution. It gathers and integrates data from newly identified public endpoints for federated access. Basic provenance information is linked to the retrieved data. Last but not least, BioFed makes use of the latest SPARQL standard (i.e., 1.1) to leverage the full benefits for query federation. The evaluation is based on 10 simple and 10 complex queries, which address data in 10 major and very popular data sources (e.g., Dugbank, Sider). BioFed is a solution for a single-point-of-access for a large number of SPARQL endpoints providing life science data. It facilitates efficient query generation for data access and provides basic provenance information in combination with the retrieved data. BioFed fully supports SPARQL 1.1 and gives access to the

Epidemiology in Germany-general development and personal experience.

Science.gov (United States)

Wichmann, Heinz-Erich

2017-08-01

Did you ever hear about epidemiology in Germany? Starting from an epidemiological desert the discipline has grown remarkably, especially during the last 10-15 years: research institutes have been established, research funding has improved, multiple curriculae in Epidemiology and Public Health are offered. This increase has been quite steep, and now the epidemiological infrastructure is much better. Several medium-sized and even big population cohorts are ongoing, and the number and quality of publications from German epidemiologists has reached a respectable level. My own career in epidemiology started in the field of environmental health. After German reunification I concentrated for many years on environmental problems in East Germany and observed the health benefits after improvement of the situation. Later, I concentrated on population-based cohorts in newborns (GINI/LISA) and adults (KORA, German National Cohort), and on biobanking. This Essay describes the development in Germany after worldwar 2, illustrated by examples of research results and build-up of epidemiological infractructures worth mentioning.

Experience with the SE in Germany

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Jochem Reichert

2008-03-01

Full Text Available A rather significant proportion of the Societas Europaeas (the European Company, or SE formed to date have had German roots. German corporate law has been enriched by an interesting alternative which meanwhile seems to have gained momentum. This contribution focuses on SEs incorporated by German entrepreneurs and provides an interesting account concerning the use of SEs in Germany in practice, such as Allianz, Fresenius, BASF and Porsche. Has the SE been used to circumvent rigid company law provisions or is it a more flexible and effective tool, perhaps, for company mobility? The practical motives behind setting up this company form are also reflected upon. These include: the facilitation of cross-border mergers; transfer of the registered office; the ‘European’ image; a more flexible form of co-determination in large companies (reduction of the number of supervisory board members; avoidance and freezing of co-determination for medium-sized enterprises; the appeal of the one-tier system and its endangerment by German co-determination; and flat and uniform structures for company groups. The author also briefly discusses some of the problems arising from the formation of SEs in Germany. He ultimately concludes that practice has shown that it is possible to work with the legal regime of the SE in Germany, which adds a new company form to those available in that Member State.

The changing consumer in Germany

DEFF Research Database (Denmark)

Grunert, Klaus G.; Grunert, Suzanne C.; Glatzer, Wolfgang

1995-01-01

Changes in economic, demographic, and cultural factors in West Germany during the past decades are briefly described, as well as changes in consumption patterns and the way the major marketing variables have been used and implemented. Special atte is paid to the upheavals caused by the German...

Energy supply in East Germany

Energy Technology Data Exchange (ETDEWEB)

Shimoyama, Tsutomu

1988-07-10

East Germany has abundant brown coal, about 90.4% of primary energy production in 1986. The high dependence upon brown coal has been established since its reevaluation in 1980 and the production is reaching a peak. Its share in power generation is also as high as 83.3% in the year. Therefore, the energy sufficiency of East Germany is about 80%. Problems are arising, however, in deterioration of excavation conditions and coal quality. Domestic energy resources such as the uranium and natural gas are also used to the maximum extent. The nuclear power has about 10% of share in the power generation. The share expansion policy is seemingly maintained even after the accident of Chernoble. Exploration, excavation and reprocessing of the uranium are conducted under the leadership of USSR. The country depends upon the oil in a very low level, less than 1%, as a result of the energy conservation policy in 1980's. (1 fig, 5 tabs)

Fire Risk Assessment in Germany

International Nuclear Information System (INIS)

Berg, H. P.

2000-01-01

Quantitative fire risk assessment can serve as an additional tool to assess the safety level of a nuclear power plant (NPP) and to set priorities for fire protection improvement measures. The recommended approach to be applied within periodic safety reviews of NPPs in Germany starts with a screening process providing critical fire zones in which a fully developed fire has the potential to both cause an initiating event and impair the function of at least one component or system critical to safety. The second step is to perform a quantitative analysis using a standard event tree has been developed with elements for fire initiation, ventilation of the room, fire detection, fire suppression, and fire propagation. In a final step, the fire induced frequency of initiating events, the main contributors and the calculated hazard state frequency for the fire event are determined. Results of the first quantitative fire risk studies performed in Germany are reported. (author)

Ultra-Wideband Notched Characteristic Fed by Coplanar Waveguide

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Rastanto Hadinegoro

2015-02-01

Full Text Available In this paper, a novel Ultra-Wide Band (UWB notch patch antenna with co-planar waveguide (CPW fed is presented. This antenna only used one layer and the patch antenna is constructed on the first layer and back to back with CPW fed and bottom part is ground plane. The width notch is used to achieve the UWB characteristic. The results shown that the impedance bandwidth is 1130 MHz (1.662–2.792 GHz or about 50.7% for VSWR <2.

FEDS : A Framework for Evaluation in Design Science Research

DEFF Research Database (Denmark)

Venable, John; Pries-Heje, Jan; Baskerville, Richard

2015-01-01

Evaluation of design artefacts and design theories is a key activity in Design Science Research (DSR), as it provides feedback for further development and (if done correctly) assures the rigour of the research. However, the extant DSR literature provides insufficient guidance on evaluation...... to enable Design Science Researchers to effectively design and incorporate evaluation activities into a DSR project that can achieve DSR goals and objectives. To address this research gap, this research paper develops, explicates, and provides evidence for the utility of a Framework for Evaluation in Design...... Science (FEDS) together with a process to guide design science researchers in developing a strategy for evaluating the artefacts they develop within a DSR project. A FEDS strategy considers why, when, how, and what to evaluate. FEDS includes a two-dimensional characterisation of DSR evaluation episodes...

A preliminary study on growth response of broiler finishers fed ...

African Journals Online (AJOL)

A preliminary study on growth response of broiler finishers fed processed mottle Mucuna beans ( Mucuna pruriens var. utilis ) ... They were fed diets (20% CP, 13 MJME/kg) incorporating 0%, 5% and 10% processed mottle “Mucuna” beans. A completely randomized design was used. Feed and water were supplied and ...

77 FR 23508 - Brass Sheet and Strip From France, Germany, Italy, and Japan

Science.gov (United States)

2012-04-19

...)] Brass Sheet and Strip From France, Germany, Italy, and Japan Determination On the basis of the record \\1... antidumping duty orders on brass sheet and strip from France, Germany, Italy, and Japan would be likely to... from France, Germany, Italy, and Japan: Investigation Nos. 731-TA-313, 314, 317, and 379 (Third Review...

2005 primary energy consumption in Germany

International Nuclear Information System (INIS)

Anon.

2006-01-01

According to preliminar calculations by the Arbeitsgemeinschaft Energiebilanzen (Working Party on Energy Balances, AGEB), the consumption of an aggregate 486 million TCE of primary energy resources in Germany last year was 1.3% below the level of the year before. Energy consumption was influenced by both the high level of prices and the development of the economy. Hardly any influence was attributable to the level of temperatures, which was largely unchanged compared to the figure of the year before. Oil consumption in 2005 in Germany dropped by nearly 2% to 174.8 million TCE. On the whole, oil with its 36% share in the energy balance remained by far the most important energy resource in Germany. Natural gas consumption of 110.4 million TCE was at the level of the year before. Its share in the primary energy balance rose slightly to 22.7%. Hard coal, because of lower use in power plants and the decline in iron making, showed a 4.6% drop in consumption to 62.8 million TCE. In this way, hard coal contributed 13% to total energy consumption. Lignite consumption dropped by 3.2% to 54.4 million TCE as a result of lower deliveries to power plants. Its 11.2% share in the total consumption of primary energy continued to make lignite the most important domestic energy resource. More than 90% of the lignite produced is used for electricity generation. The contribution to primary energy consumption of nuclear power dropped by more than 2% to 60.7 million TCE. Hydroelectric plants and wind power plants increased their contribution by 3.6%. The contribution to primary energy consumption made by all renewable energy resources rose to 4.6%. AGEB evaluates statistics of all areas of the power economy on the basis of standard criteria in order to combine these data in a comprehensive picture. Since 1994, the energy balances for Germany have been compiled by DIW on behalf of AGEB. (orig.)

Do infants fed directly from the breast have improved appetite regulation and slower growth during early childhood compared with infants fed from a bottle?

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Fisher Jennifer O

2011-08-01

Full Text Available Abstract Background Behavioral mechanisms that contribute to the association between breastfeeding and reduced obesity risk are poorly understood. The purpose of this study was to evaluate the hypothesis that feeding human milk from the breast (direct breastfeeding has a more optimal association with subsequent child appetite regulation behaviors and growth, when compared to bottle-feeding. Methods Children (n = 109 aged 3- to 6- years were retrospectively classified as directly breastfed (fed exclusively at the breast, bottle-fed human milk, or bottle-fed formula in the first three months of life. Young children's appetite regulation was examined by measuring three constructs (satiety response, food responsiveness, enjoyment of food associated with obesity risk, using the Child Eating Behavior Questionnaire. Multinomial logistic regression analyses were used to test whether children bottle-fed either human milk or formula had reduced odds of high satiety and increased odds of high food responsiveness and high enjoyment of food compared to children fed directly from the breast. Current child weight status and growth trends from 6-36 months were also examined for their relation to direct breastfeeding and appetite regulation behaviors in early childhood. Results Children fed human milk in a bottle were 67% less likely to have high satiety responsiveness compared to directly breastfed children, after controlling for child age, child weight status, maternal race/ethnicity, and maternal education. There was no association of bottle-feeding (either human milk or formula with young children's food responsiveness and enjoyment of food. There was neither an association of direct breastfeeding with current child weight status, nor was there a clear difference between directly breastfed and bottle-fed children in growth trajectories from 6- to 36-months. More rapid infant changes in weight-for-age score were associated with lower satiety responsiveness

The Reaction of West Germany to Soviet-American negotiations 1968-1972

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Katerina Alexandrovna Borisova

2015-12-01

Full Text Available This article is devoted to the analyzing of the reaction of Germany to the Strategic Arms Limitation Talks (SALT in the late 60's - early 70’s. Our attention is paid to the characteristics of executive and legislative authorities’ decisions of Germany. After Berlin and Cuban missiles crisis constant threat of a nuclear missile stability promoted the development of SALT, which should be the basic element of balance of power for the survival of human civilization. For all western countries searching for the formula to avoid the escalation of all-out war had to be based on the main principles of international relations in the context of detent of geo-political tensions between the Soviet Union and the United States. But for a long period of time West Germany still to be on the position of cold war confrontation. Such a policy could lead Germany to political isolation. After first successful steps of soviet-american’s negotiations West Germany began to realize the threat of its isolation and tried to integrate itself in the general process of detent, first of all in the field of European security. Main purpose of this research is analyzing specific mechanisms of transformation of the bilateral relations between United States and Germany, comparing different foreign policies with socialistic block, studying contradictions in the capitalist block and to identify and classify these differences, as well.

Manual: Renewable Energy Sources in Germany; Handbuch Regenerative Energiequellen in Deutschland

Energy Technology Data Exchange (ETDEWEB)

Heimann, M.

2004-07-01

One of the measures to reduce CO2 is the utilization of renewable energies. Meanwhile, Germany has come to play a leading role worldwide in this subject and is the world leader especially regarding the use of wind and solar energy. The manual called ''Renewable Energy Sources in Germany'' shows the present state of the importance of renewable energies in Germany and describes the possibilities and future potentials for the future. The author describes the ways of utilizing renewable energies in a very comprehensive manner. He assesses the medium and long-term chances of renewable energies realistically from a neutral point of view, giving the readers a well-founded basis to build their own opinions about the subject. Thus the book makes a good contribution to rationalize the discussion on renewable energies which often is lead in an emotional way. The book covers following chapters: 1) Renewable energy sources in Germany 2) Basic data on renewable energies in Germany 3) Renewable energy source in building techniques 4) Power plant and thermal plant techniques of renewable energy sources 5) Evaluation methods for renewable energies in energy supply.

Jung's views of Nazi Germany: the first year and Jung's transition.

Science.gov (United States)

Schoenl, William; Schoenl, Linda

2016-09-01

This article first considers Jung's response to the coming to power of the Nazis in Germany. It brings forth evidence that, besides wanting to preserve psychotherapy in Germany and maintain the international connection between the German and other communities of psychotherapists, he wanted to advance Jungian psychology - his psychology - in Germany. It also presents evidence that, although he occasionally made some anti-Semitic statements during this early period, he was not anti-Semitic in the way the Nazis were. The paper then argues that after Gustav Bally's criticisms in the Neue Zuercher Zeitung in February 1934, Jung entered into a transitional period that spring during which he became warier both of the Nazis and of making any statements that could be construed as being anti-Semitic. Schoenl and Peck (2012) have shown how Jung's views of Nazi Germany changed from 1933 to March 1936. This present article demonstrates very significant changes in Jung's views during the important early part of this period, that is from January 1933 - when Hitler became Chancellor of Germany - through to the spring of 1934. It draws on evidence from archival and other primary sources. © 2016, The Society of Analytical Psychology.

De la República de las Letras a Internet: de la ciudad letrada a la cibercultura y las tecnologías del S. XXI

Directory of Open Access Journals (Sweden)

Eloy Martos Núñez

2010-06-01

Full Text Available Describe la evolución del concepto de la “República de lasLetras” hacia un concepto más omnicomprensivo y tecnológico de“Ciudad Letrada” y sus implicaciones en los campos educativo y cultural. Se examinan igualmente otras controversias sobre el sentido de dichos conceptos aplicados a los contextos actuales y, en particular, en relación a Internet y los nuevos fenómenos de la sociedad de la información.

[Taxing unhealthy foods. A measure to promote public health in Germany?].

Science.gov (United States)

Lehnert, T; Riedel-Heller, S; König, H-H

2013-04-01

Due to the substantial health burden and costs caused by malnutrition in Germany, for instance as a result of obesity, diabetes, and cardiovascular diseases, the taxation of unhealthy foods/nutrients has been proposed as a possible health promoting measure. In order to evaluate whether such a fiscal intervention constitutes an effective and suitable measure to promote population health in Germany, the article outlines central empirical findings regarding malnutrition in Germany. Subsequently, the economic background (price elasticity of demand) is explained, and empirical evidence on the influence of changes in price on changes in consumption and health is presented. As a result of findings from the international literature being heterogeneous, and because very little research has been conducted in Germany on this matter until now, the taxation/subsidization of foods in order to promote population health is difficult to justify at this point.

Germany bars nuclear energy

International Nuclear Information System (INIS)

Gaullier, V.

1999-01-01

Germany wants a future without nuclear energy, the different steps about the going out of nuclear programs are recalled. The real choice is either fossil energies with their unquestionable safety levels but with an increase of the greenhouse effect or nuclear energy with its safety concerns and waste management problems but without pollutant emission. The debate will have to be set in most European countries. (A.C.)

Bullying Involvement of Korean Children in Germany and in Korea

Science.gov (United States)

Bae, Hwa-ok

2016-01-01

This study compared bullying involvement of Korean or Korean-German children living in Germany with children in Korea, and examined children's perceptions of school environment associated with bullying involvement of the children. This study included 105 Korean or Korean-German children living in the Bayern State of Germany as the study sample and…

The changing consumer in Germany

DEFF Research Database (Denmark)

Grunert, Klaus G.; Grunert, Suzanne C.; Glatzer, Wolfgang

1995-01-01

Changes in economic, demographic, and cultural factors in West Germany during the past decades are briefly described, as well as changes in consumption patterns and the way the major marketing variables have been used and implemented. Special atte is paid to the upheavals caused by the German reu...

Terminal Decline in Well-Being Differs between Residents in East Germany and West Germany

Science.gov (United States)

Vogel, Nina; Gerstorf, Denis; Ram, Nilam; Goebel, Jan; Wagner, Gert G.

2017-01-01

Lifespan research has long been interested in how contexts shape individual development. Using the separation and later reunification of Germany as a kind of natural experiment we examine whether and how living and dying in the former East or West German context has differentially shaped late-life development of well-being. We apply multi-level…

Precaution against radioactive contamination of steel products in Germany

International Nuclear Information System (INIS)

Ewers, E.; Schulz-Klemp, V.; Steffen, R.

1999-01-01

Regulations for handling of radioactive materials in Germany. Engagement of the Germany Iron and Steel Institute (VDEh) since the end of the eighties and measures taken. Level of radioactivity in uncontaminated steel products. Agreements between steel industry and scrap supplying industry as well as terms of delivery. Actual status of equipment for detection of radioactivity in the German steel plants. Demands of steel users for clean steel. (author)

Rumen microbial changes in cattle fed diets with or without salinomycin.

Science.gov (United States)

Olumeyan, D B; Nagaraja, T G; Miller, G W; Frey, R A; Boyer, J E

1986-02-01

Four rumen-fistulated steers, randomly assigned to two groups (control and salinomycin fed) were used to monitor the changes in rumen microbial populations and volatile fatty acids (VFA) concentrations associated with feeding salinomycin (0.22 mg X kg-1 X day-1). Steers were adapted to an alfalfa hay and grain (80:20) diet before supplementing the diet with salinomycin, and then the diet was changed to 50:50 and 20:80 ratios of alfalfa hay to grain at 2-week intervals. Rumen samples for total and selective enumeration of anaerobic bacteria. VFA analysis, and enumeration of protozoa were collected during the 80:20 alfalfa hay-to-grain diet before salinomycin feeding, and during the 80:20, 50:50, and 20:80 hay-to-grain diets with salinomycin. At each sampling period, rumen samples were collected at 3 h after feeding on three consecutive days. Salinomycin feeding had no effect on rumen pH and total VFA concentration. The acetate-to-propionate ratio was significantly lower in salinomycin-fed steers than in the control. The molar proportion of butyrate increased in both control and salinomycin-fed steers. Total anaerobic bacterial counts were lower in salinomycin-fed steers than in the control steers after 8 weeks of salinomycin feeding. Salinomycin-resistant bacteria increased from 7.6 to 15.6% in salinomycin-fed steers but remained unchanged in control steers. Salinomycin had no effect on cellulolytic and lactate-utilizing bacteria, but the proportion of amylolytic bacteria was higher in salinomycin-fed steers than in control steers. The total number of protozoa decreased initially in salinomycin-fed steers. The initial reduction was due to reduced numbers of Entodinium species. Holotrichs were unaffected by salinomycin feeding.

Comparison of drug abuse in Germany and China.

Science.gov (United States)

Michels, Ingo Ilja; Fang, Yu-Xia; Zhao, Dong; Zhao, Li-Yan; Lu, Lin

2007-10-01

Drug abuse has a long, but also different history in Germany and China. The Opium War largely influenced the history of China in 19th century; however, China was once recognized as a drug-free nation for 3 decades from the 1950s to the 1980s. Drug abuse has spread quickly since re-emerging as a national problem in China in the late 1980s. The number of registered drug abusers increased from 70 000 in 1990 to more than 1 million by the end of 2005. In past decades, illicit drug trafficking and production have swept most provinces in China, and drug abuse has caused many problems for both abusers and the community. One major drug-related problem is the spread of HIV, which has caused major social and economic damage in China. Germany, the largest developed European country, also faces the drug and addiction problem. Germany has about 150 000 heroin addicts, for whom HIV/AIDS has become a serious threat since the mid 1980s. To control the drug problem, the German Government adopted the pAction Plan on Drugs and Addictionq in 2003; the China Central Government approved a similar regulation in the antidrug campaign in 2005. Germany has experience in reducing drug-related harm. The methadone maintenance treatment (MMT) program has run for more than 20 years and the public has become more tolerant of addicts. In 2003, China began the MMT program for controlling the spread of HIV/AIDS. It is necessary for China to learn from developed countries to acquire success in its antidrug campaign. In this review, we will go over the differences and similarities in drug abuse between Germany and China. The differences are related to history, population and economics, drug policy context, drug laws, HIV/hepatitis C virus infection, the MMT program and so on. These 2 nations have drug abuse problems with different histories and currently use different approaches to handle illicit drug marketing and use. The legal penalties for illicit drug offences reflect the social differences of

A Chinese translation of the EdFED-Q and assessment of equivalence.

Science.gov (United States)

Lin, Li-Chan; Chang, Chia-Chi

2003-01-01

The purpose of this study was to translate the Edinburgh Feeding Evaluation in Dementia Questionnaire (EdFED-Q) from the original English into a Chinese language version and to assess the equivalence of the English and Chinese EdFED-Q versions. To use a directly translated instrument without minimal explanation of the procedures for determining the equivalence between the original and secondary language instrument is questionable. Ensuring equivalence of a translated Chinese version of the EdFED-Q for patients with dementia is an essential prerequisite for identifying culturally specific expressions of feeding difficulty under investigation. Phase 1 consisted of experts doing the initial translation into Chinese and then English back-translations of the questionnaire. Six experts determined the equality of the Chinese and English versions, and five monolingual nurses provided information for the C-EdFED-Q. In phase 2, two bilingual gerontological nurses rated 33 residents with dementia to determine equivalence across time. In phase 3, three groups of bilingual nurses used the Chinese, English, and finally both versions simultaneously to judge a model case's feeding behavior on the videotape. In phase 1, the rating on the equality of the items on the Chinese and English versions was 0.969. In phase 2, kappa coefficients for all items on the C-EdFED-Q and E-EdFED-Q ranged from 0.44 to 1.00. In determining the consistency of the scores for the C-EdFED-Q and E-EdFED-Q between the two raters across time, the intraclass correlation coefficient for the absolute agreement was found to range from 0.85 to 0.90. In phase 3, except for items 6 and 9, all items showed no significant difference among the three groups. Further studies to assess the relationship between constructs and to compare it with known and predicted relationships are recommended.

Gene expression of insulin signal-transduction pathway intermediates is lower in rats fed a beef tallow diet than in rats fed a safflower oil diet.

Science.gov (United States)

Kim, Y B; Nakajima, R; Matsuo, T; Inoue, T; Sekine, T; Komuro, M; Tamura, T; Tokuyama, K; Suzuki, M

1996-09-01

To elucidate the effects of dietary fatty acid composition on the insulin signaling pathway, we measured the gene expression of the earliest steps in the insulin action pathway in skeletal muscle of rats fed a safflower oil diet or a beef tallow diet. Rats were meal-fed an isoenergetic diet based on either safflower oil or beef tallow for 8 weeks. Both diets provided 45%, 35%, and 20% of energy as fat, carbohydrate, and protein, respectively. Insulin resistance, assessed from the diurnal rhythm of plasma glucose and insulin and the oral glucose tolerance test (OGTT), developed in rats fed a beef tallow diet. Body fat content was greater in rats fed a beef tallow diet versus a safflower oil diet. The level of insulin receptor mRNA, relative expression of the insulin receptor mRNA isoforms, and receptor protein were not affected by the composition of dietary fatty acids. The abundance of insulin receptor substrate-1 (IRS-1) and phosphatidylinositol (PI) 3-kinase mRNA and protein was significantly lower in rats fed a beef tallow diet versus a safflower oil diet. We conclude that long-term feeding of a high-fat diet with saturated fatty acids induces decrease in IRS-1 and PI 3-kinase mRNA and protein levels, causing insulin resistance in skeletal muscle.

Católicos, devociones y sociedad durante la Dictadura de Primo de Rivera y la Segunda República. La Obra del Amor Misericordioso en España (1922-1936). [Reseña

OpenAIRE

Illanes, J.L. (José Luis)

2009-01-01

Reseña de KM. REQUENA, Católicos, devociones y sociedad durante la Dictadura de Primo de Rivera y la Segunda República. La Obra del Amor Misericordioso en España (1922-1936), Biblioteca Nueva Madrid 2008, 359 pp., ISBN 978-84-9742-877-4.

A survey of environmental needs and innovative technologies in Germany

International Nuclear Information System (INIS)

Voss, C.F.; Roberds, W.J.

1995-05-01

The International Technology Program (IT?), formerly the international Technology Exchange Program (ITEP), of the Department of Energy's (DOE's) Office of Environmental Restoration and Waste Management (EM) is responsible for promoting: (1) the import of innovative technologies to better address EM's needs; and (2) the export of US services into foreign markets to enhance US competitiveness. Under this program: (1) the environmental restoration market in Germany was evaluated, including the description of the general types of environmental problems, the environmental regulations, and specific selected contaminated sites; and (2) potentially innovative environmental restoration technologies, either commercially available or under development in Germany, were identified, described and evaluated. It was found that: (1) the environmental restoration market in Germany is very large, on the order of several billion US dollars per year, with a significant portion possibly available to US businesses; and (2) a large number (54) of innovative environmental restoration technologies, which are either commercially available or under development in Germany, may have some benefit to the DOE EM program and should be considered for transfer to the US

Opportunities for smart meters in Germany

International Nuclear Information System (INIS)

Wolff, J.

2010-10-01

Germany has the ambitious goal of lowering its CO2 emission with 80 percent until 2050 as compared to 1990. Sustainable energy and the deployment of smart meters are starting to play increasingly important roles. [nl

La República de Guayaquil como sujeto de derecho internacional y su contribución en la formación del nuevo estado

OpenAIRE

Morán Herrera, Fernando Xavier

2014-01-01

El maestrante entrega tres ejemplares empastados de la tesis y tres CD con el contenido de la misma en formato PDF El presente trabajo contiene la independencia y la creación de la Provincia Libre de Guayaquil o República de Guayaquil, sus antecedentes sociales y económicos; así como las instituciones políticas civiles y militares, creadas con posterioridad a la emancipación, que sirvieron de base para la institucionalización y relativa estabilidad de un gobierno autónomo. Se narra el acc...

The Baltic policy of Germany and current international relations

Directory of Open Access Journals (Sweden)

Salikov Aleksey

2016-03-01

Full Text Available This article analyses the Baltic policy of united Germany from the 1990s until today. The authors set out to identify the significance of German-Baltic relations and the role of the Eastern policy in Russian-German relations. The method of dynamic comparison between the political and economic narrative in intergovernmental relations makes it possible to identify distinctive features of Germany’s Baltic policy in the context of current international relations. In particular, it is noted that Germany was most active in the Baltic region in the 1990s, when the country was establishing political, economic, and cultural ties with the new independent states. In the second half of the 1990s, Germany’s foreign policy became less intense. After the accession of Lithuania, Latvia, and Estonia to the EU and NATO in 2004, certain disagreements started to arise between Germany and the Baltics. It explains the lukewarm relations between them. The Ukraine events brought about a change in Germany’s regional policy. Despite Russia remaining one of the key economic and political counteractors, Germany, being a partner of the Baltics in the EU and NATO, cannot adopt a neutral position in the conflict of interests between the Baltics and Russia.

Physician assistant education in Germany

NARCIS (Netherlands)

M. Dierks; L. Kuilman; C. Matthews

2013-01-01

The first physician assistant (PA) program in Germany began in 2005. As of 2013 there are three PA programs operational, with a fourth to be inaugurated in the fall of 2013. The programs have produced approximately 100 graduates, all with a nursing background. The PA model of shifting tasks from

Photovoltaic energy generation in Germany

International Nuclear Information System (INIS)

Anon.

1993-01-01

An overview is given of the current state of the art regarding photovoltaic research and demonstration programmes in the Federal Republic of Germany. Also attention is paid to the companies and research institutes involved, and the long-term economical and technical prospects of photovoltaic energy. 13 figs., 4 tabs., 10 refs

Comparison of Bioenergy Policies in Denmark and Germany

DEFF Research Database (Denmark)

Schwarz, Gerald; Noe, Egon; Saggau, Volker

2012-01-01

Purpose – This chapter compares bioenergy policy developments in Germany and Denmark to better understand the responses of EU country policy regimes to global shocks; to examine potentially emerging new trends of productivist policy models; and to explore potential land use conflicts in the context...... of a multifunctional EU agricultural policy. Design/methodology/approach – The chapter reviews the bioenergy policy development pathways taken by Germany and Denmark, highlighting key consequences for agricultural land use and rural development. Findings from both case studies are then compared in summary tables...

Earthquakes in the Federal Republic of Germany 1977

International Nuclear Information System (INIS)

1982-01-01

The seismic data will serve as input parameters for the construction of sensitive industrial-scale facilities and also as basic data of the general specifications for building construction (DIN 4149, part 1: Building construction in seismic regions of West Germany; assumed loads, dimensioning and design of high structures). To give a better picture, the data are presented in the form of maps showing seismic regions in West Germany (including marginal regions) and world-wide. Definitions are presented in order to facilitate reading for non-experts. (orig./HP) [de

La divulgación radiofónica de la alimentación y la higiene infantil en la España de la Segunda República (1933-1935

Directory of Open Access Journals (Sweden)

Josep Bernabeu Mestre

2011-01-01

Full Text Available El trabajo analiza la incorporación de medios tecnológicos, en particular la radio, en el proceso de divulgación del conocimiento sobre la salud infantil durante la Segunda República española. En el marco de la campaña sanitaria contra la mortalidad infantil que puso en marcha la Segunda República en la década del 30, la Asociación Española de Médicos Puericultores Titulados, en colaboración con Unión Radio, organizó dos ciclos de conferencias radiofónicas que pretendían explicar, a través de un discurso divulgativo de tono descriptivo dirigido a las clases populares, las nociones fundamentales de la higiene y la alimentación infantil, e impulsar una cultura de la prevención, guiada y orientada por los dictados de los expertos. Se trataba de una acción de propaganda y divulgación que tenía su continuidad en el medio familiar y comunitario a través de la actuación de las enfermeras visitadoras puericultoras, contemplando a las madres como población diana.

FED baseline engineering studies report

Energy Technology Data Exchange (ETDEWEB)

Sager, P.H.

1983-04-01

Studies were carried out on the FED Baseline to improve design definition, establish feasibility, and reduce cost. Emphasis was placed on cost reduction, but significant feasibility concerns existed in several areas, and better design definition was required to establish feasibility and provide a better basis for cost estimates. Design definition and feasibility studies included the development of a labyrinth shield ring concept to prevent radiation streaming between the torus spool and the TF coil cryostat. The labyrinth shield concept which was developed reduced radiation streaming sufficiently to permit contact maintenance of the inboard EF coils. Various concepts of preventing arcing between adjacent shield sectors were also explored. It was concluded that installation of copper straps with molybdenum thermal radiation shields would provide the most reliable means of preventing arcing. Other design studies included torus spool electrical/structural concepts, test module shielding, torus seismic response, poloidal conditions in the magnets, disruption characteristics, and eddy current effects. These additional studies had no significant impact on cost but did confirm the feasibility of the basic FED Baseline concept.

FED baseline engineering studies report

International Nuclear Information System (INIS)

Sager, P.H.

1983-04-01

Studies were carried out on the FED Baseline to improve design definition, establish feasibility, and reduce cost. Emphasis was placed on cost reduction, but significant feasibility concerns existed in several areas, and better design definition was required to establish feasibility and provide a better basis for cost estimates. Design definition and feasibility studies included the development of a labyrinth shield ring concept to prevent radiation streaming between the torus spool and the TF coil cryostat. The labyrinth shield concept which was developed reduced radiation streaming sufficiently to permit contact maintenance of the inboard EF coils. Various concepts of preventing arcing between adjacent shield sectors were also explored. It was concluded that installation of copper straps with molybdenum thermal radiation shields would provide the most reliable means of preventing arcing. Other design studies included torus spool electrical/structural concepts, test module shielding, torus seismic response, poloidal conditions in the magnets, disruption characteristics, and eddy current effects. These additional studies had no significant impact on cost but did confirm the feasibility of the basic FED Baseline concept

The extent and impact of outsourcing: evidence from Germany

OpenAIRE

Craig P. Aubuchon; Subhayu Bandyopadhyay; Sumon Bhaumik

2012-01-01

The authors use data from several sources, including plant-level data from the manufacturing sector in Germany, to expand the literature on outsourcing. They find that, in Germany, the extent of outsourcing among manufacturing industries is higher than among service industries and that the outsourcing intensity of these industries did not change much between 1995 and 2005. They also find a statistically significantly positive impact of industry-level outsourcing intensity on German plant-leve...

República Democrática del Congo: ¿El campo estéril de los olivos?

Directory of Open Access Journals (Sweden)

Adriana María Ramírez López

2010-11-01

Full Text Available Los orígenes y las causas de la persistencia del conflicto en la República Democrática del Congo han sido explicados empleando argumentos simplificados que han tendido a minimizar la complejidad de los acontecimientos presentados en este país centroafricano desde la década de los noventa hasta el día de hoy. Estas explicaciones se caracterizan por su marcado carácter determinista y por ensombrecer aún más las perspectivas de paz de esta nación que se encuentra viviendo un coyuntural momento histórico. No obstante, una mirada más detallada al proceso de configuración del Estado poscolonial congoleño y a las dinámicas internacionales que han influido en su particular articulación pueden dar nuevas luces sobre el conflicto mismo, las causas de su prolongación y sus perspectivas de resolución.

Performance of Layers Fed Graded Levels of Blood –Rumen ...

African Journals Online (AJOL)

240 laying hens were fed graded levels of Blood-Rumen content mixture (BRCM) for a period of eight weeks. The study was designed to determine the level of BRCM that layers can tolerate in their diet. Feed intake by birds fed the control and 4% BRCM diets were comparable, but significantly higher (P<0.05) than those ...

Are Dogs Fed a Kibble-Based Diet More Likely to Experience an Episode of Gastric Dilatation Volvulus Than Dogs Fed an Alternative Diet?

Directory of Open Access Journals (Sweden)

Louise Anne Buckley

2017-04-01

Full Text Available Clinical bottom line:Most of the studies that attempt to either partially or fully address the PICO contain limitations that mean that they should either be rejected as unable to address the PICO or viewed with caution due to potential bias in the population studied. Of the two studies that remain, the findings conflict. One study found dogs fed a diet containing small particles only (<5mm, mainly dry kibble fed dogs at greater risk of GDV than those fed a diet containing large particles (>30mm, at least partly non-kibble based. The other study found no significant effect of kibble on GDV risk once other potential risk factors were controlled for in the analysis. Consequently, there is insufficient quality evidence to support the claim that feeding a kibble diet is associated with an increased risk of GDV. However, it is worth noting that no studies found that dogs fed a diet that contained no kibble (dry or moistened were at increased risk of GDV, and the addition of either table scraps, canned food or non-kibble supplements to the dog’s diet reduced the risk in some studies but more research is needed to unpack the implications of this for feeding a kibble diet.

Phytotherapy in Germany : Its Role in Self-Medication and in Medical Prescribing

OpenAIRE

LUTZ, HEIDE; Pharmaceutical Biology, Pharmaceutical Institute, University of Tuebingen

1996-01-01

This paper gives a review of the present state of herbal medicine in Germany. Phytotherapeutic drugs (herbal remedies) are of considerable importance in Germany, both in self-medication and in medical prescriptions. They represent approx. 5.4% of the prescriptions by medical doctors, and 10% of the entire domestic drug market. The Federal Health Office of the German Ministry of Health has officially evaluated the efficacy and safety of approx. 300 medicinal plants used in Germany; their evalu...

Long-run determinants of immigration to Germany 1974 - 1999: A Ricardian framework

OpenAIRE

Foders, Federico

2003-01-01

This paper examines the long-run determinants of immigration to Germany using a modified version of the Ricardo model. After a brief overview of labour flows to Germany and the related empirical literature, a Ricardian model of migration is estimated using static panel data methods. The results show that variables representing factor abundance appear to have no effect whatsoever on labour flows to Germany in a period of rising unemployment (1974–1999), while variables representing income or p...

Fertility in Austria, Germany and Switzerland:Is there a Common Pattern?

Directory of Open Access Journals (Sweden)

Tomáš Sobotka

2012-08-01

Full Text Available This article reviews major similarities and differences in period and cohort fertility in Austria, Germany and Switzerland. These three countries share a long history of low fertility and currently belong to countries with the lowest cohort fertility rates globally. The study highlights persistent differences in fertility and family patterns between Eastern and Western Germany, which are often rooted in pre-unification contrasts and can be partly linked to continuing differences in institutional set-up and norms on organised childcare, living arrangements and maternal employment. The remarkable stability in period fertility over the last 30 years (with the exception of Eastern Germany is illustrated with various indicators and discussed on the backdrop of recent reversals in European fertility trends. This stability in fertility levels contrasts with the long-term shift in childbearing towards less stable living arrangements (especially in Eastern Germany, including a high share of single mothers. The study also discusses a relatively small but persistent negative impact of the ongoing shift towards a late timing of childbearing on period fertility in the region. It highlights the educational gradient in fertility, which can be largely attributed to elevated childlessness rates among women with a higher educational degree. Migrant women have on average higher fertility rates than “native-born” women, but their net positive impact on aggregate fertility rates has diminished over time and has become negligible in Germany. A concluding discussion suggests that Austria, Germany and Switzerland share a common pattern of low fertility that sets these countries apart from other regions in Europe.

[Allergic colitis in exclusively breast-fed infants].

Science.gov (United States)

Sierra Salinas, C; Blasco Alonso, J; Olivares Sánchez, L; Barco Gálvez, A; del Río Mapelli, L

2006-02-01

Eosinophilic colitis is induced by antigens present in cow's milk proteins in formula or human milk. In the last few years, an increasing number of cases have been diagnosed in exclusively breast-fed infants. We performed a retrospective study of 13 infants diagnosed with allergic colitis in our unit between January 1997 and January 2004. All the infants had been exclusively breast-fed. In all patients, initial symptoms were digestive (12 with mucus and bloody stools). Onset of symptoms occurred at 0-3 months in 77 %. Laboratory data of the allergic compound were negative. The main locations were the descending and sigmoid colon (75 %). Biopsy demonstrated acute inflammation, with neutrophil infiltration and an increase in eosinophils. In all patients, initial treatment consisted of exclusion of cow's milk proteins from the mother's diet. Ten of the 13 patients showed no improvement, requiring exclusive administration of protein-free hydrolyzate. In 3 infants, breastfeeding was maintained (breastfeeding without cow's milk proteins plus hydrolyzate). Diagnosis of eosinophilic colitis is based on exclusion of other causes of specific colitis and typical endoscopic and ultrastructural findings. Moreover, a satisfactory response to dietary treatment must be demonstrated. This diagnosis should be considered in breast-fed infants with rectal bleeding without involvement of general health status.

Crowbar System in Doubly Fed Induction Wind Generators

Directory of Open Access Journals (Sweden)

Maurício B. C. Salles

2010-04-01

Full Text Available In the last 15 years, the use of doubly fed induction machines in modern variable-speed wind turbines has increased rapidly. This development has been driven by the cost reduction as well as the low-loss generation of Insulated Gate Bipolar Transistors (IGBT. According to new grid code requirements, wind turbines must remain connected to the grid during grid disturbances. Moreover, they must also contribute to voltage support during and after grid faults. The crowbar system is essential to avoid the disconnection of the doubly fed induction wind generators from the network during faults. The insertion of the crowbar in the rotor circuits for a short period of time enables a more efficient terminal voltage control. As a general rule, the activation and the deactivation of the crowbar system is based only on the DC-link voltage level of the back-to-back converters. In this context, the authors discuss the critical rotor speed to analyze the instability of doubly fed induction generators during grid faults.

Germany: INIS — 45 years of Reliable Nuclear Energy Information

International Nuclear Information System (INIS)

Rehme, Silke; Eck, Sabrina; Mutschelknauss, Michael

2015-01-01

The Federal Republic of Germany has been an official INIS member since 1970. The first 78 citations from German publications can be found in Issue 2 of Volume 1 of the INIS Atomindex. At that time, the Zentralstelle für Atomenergie-Dokumentation (ZAED) was the INIS center in Western Germany. To ensure that the documentation on nuclear energy was directly serving the interests of researchers working in this field, the ZAED had been recently moved from Frankfurt to the neighborhood of Kernforschungszentrum Karlsruhe, Germany’s most important nuclear research institution. After 1977, the ZAED, together with other documentation centers, was merged into what is today FIZ Karlsruhe. At the same time, publications from Eastern Germany were analyzed by the Staatliches Amt für Atomsicherheit und Strahlenschutz in Berlin from 1974 to 1989. After the German reunification, FIZ Karlsruhe became responsible for this. The share of German contributions made to the INIS database amounts to 7% of the total number of contributions. Germany has regularly ranked among the top 5 contributing Member States in the annual statistics. Regarding cooperation in INIS, Germany — represented by FIZ Karlsruhe and its predecessors — has always been actively involved, not only in contributing publications, but also in strategic planning, organization, and technical and subject matters throughout the past five decades. Germany was part of the INIS Study Team during the planning stage of INIS. Germany also hosted two ILO meetings in Karlsruhe: one in 1979 and one on the occasion of the 30th anniversary in 2000. Staff from various INIS centers worldwide often visit FIZ Karlsruhe in order to gain insight into our INIS production or to participate in internships and training sessions on workflow management, application of rules, and FIBRE usage. FIZ Karlsruhe’s many years of participation in the Voluntary Input Program, and the editing of input provided as a service to sometimes as many as 7

Labour Market Developments, Non-standard Employment and Low Wages in Germany

DEFF Research Database (Denmark)

Leschke, Janine

2014-01-01

In terms of basic labour market developments and outcomes Germany is faring comparatively well. Indeed, against the European trend, Germany saw employment rates increasing and unemployment decreasing during the economic crisis. But since the deregulatory Hartz reforms of the early and mid-2000s...

Growth, food consumption, and energy status of juvenile pallid sturgeon fed natural or artificial diets

Science.gov (United States)

Meyer, Hilary A.; Chipps, Steven R.; Graeb, Brian D. S.; Klumb, Robert A.

2016-01-01

Stocking of hatchery-raised fish is an important part of the pallid sturgeon Scaphirhynchus albus recovery program. In the wild, juvenile pallid sturgeon consume primarily aquatic insects, although little is known about specific dietary needs. In hatchery settings, pallid sturgeon are fed commercial diets that are formulated for salmonids. To compare food consumption, growth, and energy status of pallid sturgeon fed artificial or natural diets, we conducted a laboratory study using 24 juvenile pallid sturgeon (initial fork length 153–236 mm). Pallid sturgeon were fed a daily ration of either commercial pellets (1 mm, slow sinking; 45% protein, 19% fat) or chironomid larvae for 5 wk. Natural-fed pallid sturgeon exhibited a greater specific growth rate (2.12% d−1) than pellet-fed fish (0.06% d−1). Similarly, relative condition was greater for natural-fed sturgeon (Kn = 1.11) than that observed for pellet-fed fish (Kn = 0.87). In contrast, the hepatosomatic index was significantly higher in pellet-fed fish (2.5%), indicating a high lipid diet compared with natural-fed sturgeon (1.4%). Given the importance of natural diets to fish digestion and growth, it is suggested that a more holistic approach be applied in the development of a practical diet for pallid sturgeon that incorporates attributes of natural prey.

American foulbrood of the honey bee: occurrence and distribution of different genotypes of Paenibacillus larvae in the administrative district of Arnsberg (North Rhine-Westphalia).

Science.gov (United States)

Peters, M; Kilwinski, J; Beringhoff, A; Reckling, D; Genersch, E

2006-03-01

Between March 2003 and October 2004, Paenibacillus larvae, the aetiological agent of American foulbrood disease of the honey bee, was isolated from broodcombs and honey samples of 54 apiaries in the administrative district of Arnsberg (North Rhine-Westphalia, Germany). Genotyping of 176 P. larvae isolates with repetitive element polymerase chain reaction fingerprinting (rep-PCR) using BOX A1R and MBO REP1 primers revealed five different genotypes (AB, Ab, ab, ass, Acapital BE, Cyrillic). In samples of three apiaries, more than one genotype was detected. A combination of two genotypes was isolated from honey samples of the same hive two times (ab/ass and Ab/ab). The five genotypes were not randomly distributed in the district, but revealed a certain geographical clustering. Possible factors with impact on the genotype diversity and the distribution pattern are discussed.

La sociedad civil movilizada y las reformas democráticas en la República Dominicana

Directory of Open Access Journals (Sweden)

Rosario Espinal

2001-01-01

Full Text Available En este artículo se identifican cinco periodos en el proceso de organización y movilización social que se produjo en la República Dominicana entre 1978 y 2000, el lapso más largo de apertura política que ha tenido el país. Se plantea que la naturaleza y la forma de estos movimientos ha variado como resultado de la situación económica, el partido en el poder, las estrategias de distintos gobiernos para ejercer control social sobre los grupos movilizados, el tipo de relación entre los partidos políticos y las organizaciones sociales y el financiamiento disponible para las organizaciones sociales. En cuanto al debate teórico sobre la relación entre movimientos sociales y democracia, se plantea que esta relación no es unívoca, y que en determinadas circunstancias los movimientos sociales pueden ayudar a la democratización y en otras a obstaculizarla

Financing long term liabilities (Germany)

International Nuclear Information System (INIS)

2003-01-01

In Germany the basis for the management of radioactive residues is the polluter-pays principle. All steps of treatment of radioactive waste arising from operation, decommissioning and dismantling including conditioning, interim storage and disposal of radioactive waste have to be financed by the waste producers. The waste producers are responsible for the harmless recycling of the residues or for their orderly management as radioactive waste. The Federal Government is responsible for establishing disposal facilities. Accordingly the waste producers are constructing and operating facilities in which the radioactive residues can be treated and stored until their disposal. As far as the radioactive waste cannot be stored by the producer, waste originating from research, medicine and industry can be stored in surface storage facilities of the federal states. Spent fuel from German NPPs is partly reprocessed in France and UK. The rest has to be disposed off directly in deep geologic formations. Until a repository for spent fuel is available in Germany spent fuel will be stored in interim storage facilities on the sites of the NPPs. The storage will take place in casks in a dry way. In exceptional cases, if the storage at a NPP site is not possible, there are two central storages at Ahaus and Gorleben which are in operation and can be made available as reserve. Radioactive waste returning from the reprocessing of German spent fuel in France and UK is stored in the Gorleben central storage. The Federal Government is aiming to establish a repository in deep geological formations about the year 2030 which shall be available for all types and quantities of radioactive waste. The necessary expenses for the planning and construction of radioactive waste disposal facilities are initially carried by the Federal Government. The Government recovers the costs by contributions or advance payments from the waste producers. The use of storage and disposal facilities is financed by

Imagining difference : The experiences of 'transnational' Indian IT-professionals in Germany

NARCIS (Netherlands)

Meijering, L; van Hoven, B

In this paper we explore the motivations to migrate and the migration experiences of 22 Indian IT professionals in Germany. When studying skilled migration, Germany is an interesting case as it struggled with waves of extreme right activities whilst trying to attract IT professionals from outside

Fatty acid intake alters growth and immunity in milk-fed calves.

Science.gov (United States)

Hill, T M; Vandehaar, M J; Sordillo, L M; Catherman, D R; Bateman, H G; Schlotterbeck, R L

2011-08-01

The aim of the present study was to determine the effect of supplementing milk replacer (MR) with NeoTec4 (Provimi North America, Brookville, OH), a commercially available blend of butyric acid, coconut oil, and flax oil, on calf growth, efficiency, and indices of immune function. In trial 1a, 48 male Holstein calves were fed either a control MR that contained only animal fat or the same MR with NeoTec4 (treatment) along with free-choice starter. The MR (28.7% crude protein, 15.6% fat) was fed at an average of 1 kg of dry matter (DM)/d. In trial 1b, weaned calves from trial 1a were all fed dry starter for 28 d without NeoTec4 (phase 1), and then half the calves were fed NeoTec4 for 28 d (phase 2). In trial 2, 40 male Holstein calves were fed a control MR with lard, coconut oil, and soy lecithin or the same MR supplemented with NeoTec4 (treatment). The MR (22.8% crude protein, 18.9% fat) was fed at an average of 1 kg of DM/d; no starter was fed. In trial 1a, NeoTec4 improved average daily gain, feed intake, and feed efficiency, reduced the number of days that calves experienced scours, and reduced the medical treatments for clostridium sickness. In trials 1a and 2, NeoTec4 altered the inflammatory response to vaccination with Pasteurella at 5 wk of age and to challenge with Salmonella toxin at less than 2 wk of age (fed NeoTec4 for 6 d), as observed by reduced hyperthermia and hypophagia, and altered the tumor necrosis factor-α response. In addition, NeoTec4 enhanced the response in IL-4 and globular protein estimates postchallenge and enhanced titers for bovine viral diarrhea and respiratory parainfluenza-3. Postchallenge serum concentrations of albumin were lower and urea nitrogen concentrations were greater in control calves than in calves fed NeoTec4. In trial 1b, performance did not differ during the first 28 d when no calves received NeoTec4, but calves receiving NeoTec4 in the second 28 d had greater average daily gain and feed efficiency. We conclude that

Polarization and Rising Wage Inequality: Comparing the U.S. and Germany

Directory of Open Access Journals (Sweden)

Dirk Antonczyk

2018-04-01

Full Text Available Since the late 1970s, wage inequality has increased strongly both in the U.S. and Germany but the trends have been different. Wage inequality increased along the entire wage distribution during the 1980s in the U.S. and since the mid 1990s in Germany. There is evidence for wage polarization in the U.S. in the 1990s, and the increase in wage inequality in Germany was restricted to the top of the distribution before the 1990s. Using an approach developed by MaCurdy and Mroz (1995 to separate age, time, and cohort effects, we find a large role played by cohort effects in Germany, while we find only small cohort effects in the U.S. Employment trends in both countries are consistent with polarization since the 1990s. The evidence is consistent with a technology-driven polarization of the labor market, but this cannot explain the country specific differences.

Ulceroglandular tularemia in a toddler in Germany after a mosquito bite.

Science.gov (United States)

Hanke, Christof A; Otten, Joerg-Elard; Berner, Reinhard; Serr, Annerose; Splettstoesser, Wolf; von Schnakenburg, Christian

2009-08-01

Although tularemia is a long-known disease, its significance had diminished over the last decades in Middle Europe. However, over the past years, there is new evidence suggesting that tularemia has re-emerged in Germany. In 2007, the highest number of human cases for almost 50 years has been notified. Beside typical vectors, new ways of transmission seem to gain significance. So far, mosquito bite-transmitted tularemia has only been known from Scandinavia but not from Middle Europe. We report the first case of a 1-year-old toddler from Southwestern Germany with mosquito bite-associated ulceroglandular tularaemia. The new and interesting features of this case are the young age of the patient and the unusual transmission route. The available data suggesting changes in the epidemiology for tularemia in Germany are reviewed. This is an interesting case of infantile tularemia with a very unusual transmission route, highlighting ongoing changes in the epidemiology of tularemia in Germany.

Neurosurgical Resident Training in Germany.

Science.gov (United States)

Stienen, Martin N; Gempt, Jens; Gautschi, Oliver P; Demetriades, Andreas K; Netuka, David; Kuhlen, Dominique E; Schaller, Karl; Ringel, Florian

2017-07-01

Introduction  Efficient neurosurgical training is of paramount importance to provide continuing high-quality medical care to patients. In this era of law-enforced working hour restrictions, however, maintaining high-quality training can be a challenge and requires some restructuring. We evaluated the current status of resident training in Germany. Methods  An electronic survey was sent to European neurosurgical trainees between June 2014 and March 2015. The responses of German trainees were compared with those of trainees from other European countries. Logistic regression analysis was performed to assess the effect size of the relationship between a trainee being from Germany and the outcome (e.g., satisfaction, working time). Results  Of 532 responses, 95 were from German trainees (17.8%). In a multivariate analysis corrected for baseline group differences, German trainees were 29% as likely as non-German trainees to be satisfied with clinical lectures given at their teaching facility (odds ratio [OR]: 0.29; 95% confidence interval [CI]: 0.18-0.49; p  hours as requested from the European Working Time Directive 2003/88/EC, and in an international comparison, German trainees were twice as likely to work > 50 hours per week (OR: 2.13; 95% CI, 1.25-3.61; p  = 0.005). This working time, however, is less spent in the operating suite (OR: 0.26; 95% CI, 0.11-0.59; p  = 0.001) and more doing administrative work (OR: 1.83; 95% CI, 1.13-2.96; p  = 0.015). Conclusion  Some theoretical and practical aspects of neurosurgical training are superior, but a considerable proportion of relevant aspects are inferior in Germany compared with other European countries. The present analyses provide the opportunity for a critical review of the local conditions in German training facilities. Georg Thieme Verlag KG Stuttgart · New York.

Frequency of polyploid cells in the bone marrow of rats fed irradiated wheat

International Nuclear Information System (INIS)

George, K.P.; Chaubey, R.C.; Sundaram, K.; Gopal-Ayengar, A.R.

1976-01-01

Diets containing different proportions of non-irradiated or irradiated wheat were fed to Wistar rats for 1 or 6 wk. Cytological analysis of the bone marrow showed no significant difference in the frequency of polyploid cells in the rats fed non-irradiated or irradiated wheat diets, even when the treated wheat was fed to the rats within 24 hr of irradiation. (author)

Energy R and D in Germany; TOPICAL

International Nuclear Information System (INIS)

PJ Runci

1999-01-01

Germany's total national (i.e., combined public and private sector) funding for R and D stood at$42 billion in 1997. The private sector accounted for nearly 62% ($24 billion) of the total, while the public sector accounted for approximately 38%. Since the late 1970s, when the public and private sectors each funded roughly half of Germany's R and D, the private sector has steadily assumed a larger and larger role as the dominant supporter of R and D activity, while overall government funding has remained essentially flat for much of the past two decades. In addition to declining relative to private R and D expenditures, public R and D expenditures in Germany declined by 4% in real terms between 1991 and 1997, to approximately$15 billion. The reduction in R and D investments in the public sector can be attributed in large part to the financial challenges associated with German reunification and related shifts in social priorities including efforts to address high unemployment and to rebuild basic infrastructure in the eastern states. R and D expenditures have also declined as a percentage of the total public budget, from a peak of 3.4% in 1985 to 2.7% in 1996. Energy R and D has been the hardest hit of all major socioeconomic areas of R and D expenditure funded by the German government. Between 1981 and 1997, public energy R and D fell from approximately$1.6 billion to$400 million--a 75% real decline. The$850 million reduction in Germany's fission R and D budget (which constituted two-thirds of government R and D investment in 1985) explains some 90% of the funding decline. Negative public perceptions regarding the safety and environmental impacts of nuclear energy have reduced nuclear power's viability as a long-term energy option for Germany. Discussions of a complete nuclear phaseout are now under way. At the same time, the German government has slashed its investments in fossil energy R and D by more than 90%. While energy efficiency and renewable energy

Germany restores funds to grant agencies

CERN Multimedia

Schiermeier, Q

1998-01-01

Edelgard Bulmahn, the research minister for Germany's coalition government is to make up a shortfall in the budgets of the Max Planck Society (MPS) and the Deutsche Forshungsgemeinschaft (DFG) and will add an extra five per cent to each in 1999.

A Constituição da República de 1988 e a hierarquia dos Tratados de Direitos Humanos no ordenamento jurídico brasileiro

Directory of Open Access Journals (Sweden)

Julio Cesar de Aguiar

2016-11-01

Full Text Available O presente artigo busca analisar o modo pelo qual o Direito brasileiro – em especial a Constituição da República de 1988 – se relaciona com os instrumentos internacionais de proteção aos direitos humanos, bem como abordar a problemática da hierarquização “diferenciada” e a contribuição ofertada por estes instrumentos para o aperfeiçoamento do ordenamento jurídico interno, em um contexto histórico do período pós-Segunda Guerra Mundial, quando a comunidade internacional passou não só a reconhecer, mas também a dar mais importância à proteção aos direitos humanos, os quais são questões de legítimos interesses e preocupação internacional. Por fim, apesar de prevalecer o entendimento - da jurisprudência do STF - de que os acordos que versem sobre direitos humanos, se aprovados no Congresso Nacional com quórum e procedimento de Emenda Constitucional, têm a mesma hierarquia da Constituição, caso contrário, adquirem status superior às leis complementares e ordinária e inferior à Constituição, status de supra legalidade, há ainda, a discussão para saber qual o verdadeiro sentido do parágrafo 3º do Art. 5º Constituição da República de 1988.

Growth curves and their implications in hand-fed Monk parrots (Myiopsitta monachus

Directory of Open Access Journals (Sweden)

Petzinger C

2015-10-01

Full Text Available Christina Petzinger,1,2 J Jill Heatley,3 John E Bauer1,2 1Comparative Animal Nutrition Research Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, 2Intercollegiate Faculty of Nutrition, Texas A&M University, 3Zoological Medicine Service, Department of Small Animal Medicine and Surgery, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA Abstract: Monk parrots (Myiopsitta monachus were hand-fed over two chick seasons spanning of 2010 to 2011. Information from the growth curve of chicks hand-fed in 2010 was used to develop a feeding protocol for the 2011 season (Protocol-2011. This protocol addressed the problems of delayed followed by excessive growth experienced by parrots hand fed in 2010. Monk parrots that were hand-fed in 2011 following the new protocol experienced delayed growth after 20 days of age. However, some Monk parrots were fed in excess of Protocol-2011 and did not experience a major delay in growth. The energy requirement equations used to construct Protocol-2011 were low when compared to adult Monk parrot maintenance energy requirements. The data suggest that growing birds do not require approximately twice their adult maintenance energy requirements, as is the case for growing dogs. Additionally, there appear to be fluctuations in energy needs as Monk parrots grow. A major increase in energy needs occurred between days 18 and 23 posthatching, which corresponds to feather development and growth in Monk parrot chicks. Thus, multiple equations estimating energy requirements, rather than just one equation, are likely needed from hatching to fledging in order to ensure adequate energy is provided to chicks. More research on the energy requirements of growing Monk parrots, especially around the time of fledging and weaning, is needed to improve hand-fed methods and potentially the adult health of hand-fed birds. Keywords

[AIDS prevention in Germany].

Science.gov (United States)

Pott, E

2007-04-01

In 1987 the national AIDS prevention campaign "Gib AIDS keine Chance" (Don't give AIDS a chance) was started in Germany. After a very difficult and controversial political debate about a probably successful response to AIDS, in the end a political decision was made in favour of the implementation of a long term "social learning strategy". Thus, since then the Bundeszentrale für gesundheitliche Aufklärung (Federal Centre for Health Education, BZgA) has been running the campaign on behalf of the Federal Ministry of Health. The result of this prevention program is a low rate of infections. In Germany there were 2600 newly diagnosed infections in 2005: 59 % in homosexual men, 16 % by heterosexual contacts, 17 % in people from high prevalence countries and 7 % in i.v. drug users. In comparison to the international situation Germany has a relatively low HIV-prevalence even nowadays. However, Germany has also been confronted with an increasing number of newly diagnosed infections in the last few years. When the prevention program was started it was very important to build new structures for a successful implementation of the campaign. That meant for instance to build up an effective infrastructure for cooperation between the governmental and the nongovernmental sector, including organising the coordinated action among the partners at the federal, regional and local levels. Likewise, international networking was of great importance. A key element, relevant for the success of the campaign was the close cooperation at the federal level between the BZgA and the Deutsche AIDS Hilfe (German AIDS Help, DAH), to combine the highreach intervention in low-prevalence populations with intensive interventions for high prevalence groups. An effective national AIDS prevention campaign must reach the whole population; inform the public about the main risks of infection, about methods of protection and about what is not infectious. Moreover groups with a higher level of risk of

Low serum biotin in Japanese children fed with hydrolysate formula.

Science.gov (United States)

Sato, Yasuhiro; Wakabayashi, Kenji; Ogawa, Eishin; Kodama, Hiroko; Mimaki, Masakazu

2016-09-01

Given that nutritional biotin deficiency in Japanese infants has been reported, a straightforward method for estimating biotin level is needed. The biotin content in infant formula, breast milk, and the sera of infants fed with various types of formula were measured using avidin-binding assay. A commercially available ELISA kit was used for the measurement of biotin in 54 types of formula, including hydrolysate formulas for milk allergy, as well as in breast milk and in the sera of 27 infants fed with these formulas. The biotin content reached the recommended value in only five formulas. All of the hydrolysate formulas and more than half of the special formulas contained biotin biotin was low in infants fed only with the hydrolysate formulas, and one of them had alopecia related to biotin deficiency. While many were asymptomatic, infants fed with formulas lacking biotin are at risk of developing symptomatic disease. The addition of biotin to breast milk substitutes was finally approved in the middle of 2014, however pediatricians in Japan should still be vigilant with regard to nutritional biotin deficiency in infants for the time being. © 2016 Japan Pediatric Society.

Weight Gain Of Broiler Chicks Fed A Maize-Soya bean Diet ...

African Journals Online (AJOL)

An experiment was carried out to investigate the effect of substituting synthetic methionine with sodium sulphate and sodium sulphite in a maize-soyabean diet fed to broiler chicks. Two hundred and forty (240) unsexed Hubbard day old broiler chicks were fed iso-caloric and iso-trogenous maize-soyabean ...

Dual-Electrical-Port Control of Cascaded Doubly-Fed Induction Machine for EV/HEV Applications

DEFF Research Database (Denmark)

Han, Peng; Cheng, Ming; Chen, Zhe

2017-01-01

that of the power machine in singly-fed operation mode, and only a half of that of the power machine in doubly-fed operation mode, which shows the urgent need for torque density enhancement of brushless doubly-fed machines for electric vehicle/hybrid electric vehicle applications. Computer simulations...

Germany forms alliance for terascale physics

CERN Multimedia

Feder, Toni

2007-01-01

"Germany's high-energy particle physicists have formed a network to increase their international visibility and competitiveness as their field gears up for the start next ear of the Large Hadron Collide (LHC) at CERN and, eventually, the International Linear Collider." (1 page)

Performance of broilers fed on diets containing different amounts of chaya (Cnidoscolus aconitifolius) leaf meal.

Science.gov (United States)

Sarmiento-Franco, L; McNab, J M; Pearson, R A; Belmar-Casso, R

2002-05-01

The performance and gut measurements of broilers fed on diets containing different amounts of chaya (Cnidoscolus aconitifolius) leaf meal (CLM) were examined in two experiments. In the first experiment, 60 Hubbard chickens (30 males and 30 females; 2 weeks old) were fed on five maize diets; these were formulated using 0, 150 (CLM150), 250 (CLM250) or 350 (CLM350) g CLM/kg, and the fifth diet contained soyabean. In the second experiment, 148 Ross male chicks, 1 day old, were fed on three isonitrogenous and isoenergetic maize-soyabean-based diets, which included 0 (control), 150 (C150) or 250 (C250) g CLM/kg. The diets were offered ad libitum for 2 or 3 weeks in the first and second experiments, respectively. Food intake, weight gain and the food:weight gain ratio were recorded. The weight of the gizzard and intestine and the weight and length of the caeca were also determined in the second experiment. In experiment 1, the birds fed on the maize-soyabean diet had a higher (p < 0.05) weight gain and final weight than birds fed on maize only or on the CLM150 diets. There were no differences for any of the variables studied between the birds fed on the maize-soyabean diet and those fed on the CLM250, nor between males and females. In the second experiment, weight gain, food intake and the food:weight gain ratio for birds fed on C250 were lower (p < 0.05) than those in birds fed on either the control or C150 diets. The weights of the gizzard and intestine were the lowest and the highest, respectively, in birds fed on C250 (p < 0.05). The length and weight of the caecum from birds fed on the control diet were lower (p < 0.05) than those of birds fed on either the C150 or C250 diets. The results from this study suggest that CLM may be included up to 150 g/kg in commercial diets without having an adverse effect on poultry performance, and may also be mixed with maize up to 250 g/kg to improve the performance of chickens fed on low-protein diets.

Prophage lambda induction (Inductest) of blood of rats fed irradiated spices

Energy Technology Data Exchange (ETDEWEB)

Farkas, J; Andrassy, E [Koezponti Elelmiszeripari Kutato Intezet, Budapest (Hungary)

1981-01-01

Lysogenic Escherichia coli K12 strains Nos. GY 5023: envA uvr/sup +/ (lambda) and GY 5027: envA uvrB (lambda) were used as test organisms and E.coli strain No. GY 4015 as the indicator to investigate prophage induction (Inductest) of blood samples of CFY rats fed with black pepper and spice mixture treated with gamma radiation. The dose levels applied for the irradiation of spices were 0.5 and 15 kGy. In the rat feed, the applied concentration of ground black pepper was 3.5%, and that of the spice mixture (: mild paprika, black pepper, allspice, coriander, marjoram, cumin and nutmeg) was 25%. Blood samples were taken for prophage induction after six days' feeding with the tested diet. Tests with pepper were performed both within two weaks after irradiation and again after 90 days of storage following irradiation, while with the spice mixture, Inductest was performed with the blood of rats fed with a spice mixture irradiated 90 days before the start of the feeding test. Neither the blood of rats fed with irradiated pepper nor that of rats fed with irradiated spice mixture did increase, to a statistically significant degree, the occurrence of prophage induction as compared with blood samples of rats fed with a diet containing untreated spices or with commercial rat feed. In agreement with earlier microbial mutagenicity tests performed with extracts of irradiated spices and urine of rats fed with irradiated spices, neither did the present results indicate that spices irradiated with 5 and 15 kGy or their metabolites would be of DNA-modofying potential.

Prophage lambda induction (Inductest) of blood of rats fed irradiated spices

International Nuclear Information System (INIS)

Farkas, J.; Andrassy, E.

1981-01-01

Lysogenic Escherichia coli K12 strains Nos. GY 5023: envA uvr + (lambda) and GY 5027: envA uvrB (lambda) were used as test organisms and E.coli strain No. GY 4015 as the indicator to investigate prophage induction (Inductest) of blood samples of CFY rats fed with black pepper and spice mixture treated with gamma radiation. The dose levels applied for the irradiation of spices were 0.5 and 15 kGy. In the rat feed, the applied concentration of ground black pepper was 3.5%, and that of the spice mixture (: mild paprika, black pepper, allspice, coriander, marjoram, cumin and nutmeg) was 25%. Blood samples were taken for prophage induction after six days' feeding with the tested diet. Tests with pepper were performed both within two weaks after irradiation and again after 90 days of storage following irradiation, while with the spice mixture, Inductest was performed with the blood of rats fed with a spice mixture irradiated 90 days before the start of the feeding test. Neither the blood of rats fed with irradiated pepper nor that of rats fed with irradiated spice mixture did increase, to a statistically significant degree, the occurrence of prophage induction as compared with blood samples of rats fed with a diet containing untreated spices or with commercial rat feed. In agreement with earlier microbial mutagenicity tests performed with extracts of irradiated spices and urine of rats fed with irradiated spices, neither did the present results indicate that spices irradiated with 5 and 15 kGy or their metabolites would be of DNA-modofying potential. (author)

The principles of nuclear safety in the Federal Republic of Germany

International Nuclear Information System (INIS)

Pfaffelhuler, J.K.

1980-01-01

A survey of the nuclear installations in the Federal Republic of Germany is presented. Also, the necessary preparations for a country, which wants to introduce nuclear power and the legal basis, the technical principles and the licensing procedure as practised in the Federal Republic of Germany are discussed. (A.L.) [pt

Triglyceride kinetics in fasted and fed E.coli septic rats

International Nuclear Information System (INIS)

Lanza-Jacoby, S.; Tabares, A.

1990-01-01

The mechanism for the development of hypertriglyceridemia during gram-negative sepsis was studies by examining the liver production and clearance of very-low-density lipoprotein (VLDL) triglyceride (TG). To assess the liver output and peripheral clearance the kinetics of VLDL-TG were determined by a constant intravenous infusion of [2- 3 H] glycerol-labeled VLDL in fasted control, fasted E. coli-treated, fed control, and fed E.coli-treated rats. Lewis inbred rats, 275-300 g, were made septic with 8 x 10 7 live E.coli colonies per 100 g body weight. Twenty-four hours following E.coli injection serum TG of fasted E.coli-treated rats was elevated by 170% which was attributed to a 67% decrease in the clearance rate of VLDL-TG in fasted E.coli-treated rats compared with their fasted controls. The secretion of VLDL-TG declined by 31% in the livers of the fasted E.coli-treated rats which was accompanied by a 2-fold increase in the composition of liver TG. In a second series of experiments control and E.coli-treated rats were fed intragastrically (IG) a balanced solution containing glucose plus fat as the sources of nonprotein calories. Serum TG were 26% lower in the fed E.coli-treated rats because the clearance rate increased by 86%. The secretion of TG in the fed septic rats increased by 40% but this difference was not significant. In the septic rat the ability to clear triglycerides from the plasma depends upon the nutritional state

Disintegration and Violence among Migrants in Germany: Turkish and Russian Youths versus German Youths

Science.gov (United States)

Baier, Dirk; Pfeiffer, Christian

2008-01-01

Turkish and Russian immigrants are the two largest groups of immigrants in Germany, but there are some important differences regarding their legal status. Although most of the Turkish adolescents were born in Germany, few of them have German citizenship. In contrast, most of the Russian youths were born outside Germany, but they mostly possess…

Are dogs that are fed from a raised bowl at an increased risk of gastric dilation volvulus compared with floor-fed dogs?

OpenAIRE

Buckley, L.A.

2017-01-01

There are only two studies that study the effect of raised feeders on the risk of Gastric Dilatation Volvulus (GDV) and their findings conflict. Only one study found a significant effect of feeder height, with large and giant breeds fed from a raised feeder being at an increased risk of GDV floor fed dogs. However, these authors found that, where the feeder was raised, the height of the feeder that increased the GDV risk was affected by the size of the dog. Large breed dogs were more likely t...

[Disaster Control and Civil Protection in Germany].

Science.gov (United States)

Kippnich, Maximilian; Kowalzik, Barbara; Cermak, Rudolf; Kippnich, Uwe; Kranke, Peter; Wurmb, Thomas

2017-09-01

The train crash of Bad Aibling/Germany in February 2016 and the terrorist attacks of the recent years in Europe have demonstrated the urgent need to be prepared for such disastrous events. Disaster preparedness and disaster control are very important governmental duties, as are civil protection and civil defense. In Germany the responsibility for those tasks are divided between the 16 "Länder" and the Federation. While the Federation takes care of the civil protection and disaster assistance, the Länder are responsible for disaster control. The presented article focuses on these issues and gives valuable insights into the German system of disaster control and civil protection with a focus on health protection. Georg Thieme Verlag KG Stuttgart · New York.

[Migrants of high social status in Germany].

Science.gov (United States)

Glebe, G

1997-01-01

"The accelerating economic globalization has created a growing demand for highly skilled labourers. As a result, there has been an increase in highly skilled and high-status migrants to Germany, especially to the urban agglomerations with global city functions. This migration process is carried mostly by the internal labour and job movement of multinational companies. In the urban centres these groups of migrants follow specific patterns of spatial organization and segregation with regard to their place of residence. But they also have other distinctive difference to the migrants with a lower social status, such as higher social acceptance in their host country, the transitory character of their stay in Germany, and their intentions to return to their home countries." (EXCERPT)

Strategic Interests of Germany in the Balkans at the Turn of 20-21 Centuries

Directory of Open Access Journals (Sweden)

Andrey Latkov

2014-01-01

Full Text Available After the reunification of Germany and the transition of some countries of central and Eastern Europe under the control of the West, radical changes in the European political system have occurred. Germany turned into a powerful state and began to provide the strategy for independent foreign policy, in which the regional policy in the Balkans, Caucasus and Middle East took the significant place. Germany tried to expand its influence to the countries of Balkan Peninsula, in alliance with Austria-Hungary against Russia, as well as in the beginning of 21st century. However, in the end of 20th century, after several failures in the foreign policy, Germany turned to Russia. Despite its expansionist policy, Germany had to coordinate every step with international organizations or even transfer them issues of conflict resolution in the region. Constantly competing with its allies (mainly the U.S. and UK, Germany was trying to build its foreign policy strategy in the way of increasing its influence in the strategically important region.

La "Carta a los maestros" de Jules Ferry (1883 y el laicismo escolar de la IIIª República francesa

Directory of Open Access Journals (Sweden)

Juan Manuel FERNÁNDEZ SORIA

2010-03-01

Full Text Available RESUMEN: Partiendo del valor histórico —de lo que es una muestra su influencia en la política educativa de la Segunda República española— y de la proyección de su legado en nuestros días de la «Carta a los Maestros» (1883 del ministro francés de Instrucción Pública, Jules Ferry, este trabajo se acerca a la vida de su autor y a su política educativa para analizar luego con mayor profundidad los aspectos más sobresalientes del documento —que transcribimos en francés y castellano—, especialmente el laicismo escolar, como medio de establecer una escuela nacional y de fundación de la República, la defensa de la moral común y positiva, los modos y procedimientos —tanto directos como indirectos— de su enseñanza, así como el papel del maestro y del manual en la educación moral y cívica del futuro ciudadano. ABSTRACT: Starting with the historic value —of which it is an example its influence in the educational policy of the Second Republic— and with the influence that remains in our days, of the legate of the «Elementary Schoolteacher’s Letter», written by Jules Ferry, French minister of the Public Instruction, this piece of work approaches to its author’s life and to its educational policy in order to analyse later in greater detail the most relevant aspects of the document —which we reproduce in Spanish and French— specially the scholastic laicism as a way to establish a national school, and the foundation of the Republic, the defence of common and positive morality, the ways and procedures, both direct and indirect, of its teaching, and also the role of schoolteachers and the guide in the moral and civic education of the future citizens.

ECFA SURVEY: Germany

International Nuclear Information System (INIS)

Anon.

1994-01-01

Few nations can match the scope of German basic physics contributions. Earlier this century, illustrious names (Rontgen, Franck, von Laue, Planck, Sommerfeld, Heisenberg, ) kept Germany among the front runners. Subsequent history has given German physics a very different profile - the country now participates massively in international projects and is the largest single contributing nation in CERN's research programme. At the same time, an impressive high energy programme at the German national Laboratory at DESY, Hamburg, centred around the 6.3 kilometre HERA ring, the world's only high energy electron-proton collider, attracts scientists from all over the world

Survival of Patients with Oral Cavity Cancer in Germany

Science.gov (United States)

Listl, Stefan; Jansen, Lina; Stenzinger, Albrecht; Freier, Kolja; Emrich, Katharina; Holleczek, Bernd; Katalinic, Alexander; Gondos, Adam; Brenner, Hermann

2013-01-01

The purpose of the present study was to describe the survival of patients diagnosed with oral cavity cancer in Germany. The analyses relied on data from eleven population-based cancer registries in Germany covering a population of 33 million inhabitants. Patients with a diagnosis of oral cavity cancer (ICD-10: C00-06) between 1997 and 2006 are included. Period analysis for 2002–2006 was applied to estimate five-year age-standardized relative survival, taking into account patients' sex as well as grade and tumor stage. Overall five-year relative survival for oral cavity cancer patients was 54.6%. According to tumor localization, five-year survival was 86.5% for lip cancer, 48.1% for tongue cancer and 51.7% for other regions of the oral cavity. Differences in survival were identified with respect to age, sex, tumor grade and stage. The present study is the first to provide a comprehensive overview on survival of oral cavity cancer patients in Germany. PMID:23349710

Environment and economic growth in the federal republic of Germany

International Nuclear Information System (INIS)

Bertsch, F.

1998-01-01

After several decades of economic growth with a continuous increase of energy consumptions, a new trend is now developing in Germany: reduction of energy consumptions and of pollutant emissions. This paper analyzes first the energy supplies of Germany (consumption, sources), the consumption by sector, and the share of the different energy sources in the German consumption (petroleum, coal, natural gas, nuclear power, and renewable energies). In a second part, the German energy policy is presented with its priorities and actions regarding the environment protection: energy savings, development of renewable energy sources, reduction of automotive fuels consumption, rational use of energy, thermal insulation of buildings, financial incentives etc.. Finally, the forecasting of future energy consumption and pollutants emission trends in Germany and at the worldwide scale are evoked. (J.S.)

The School-HE Interface in West Germany.

Science.gov (United States)

Schmithals, F.

1986-01-01

Discusses the concerns and problems associated with the secondary school-higher education interface in West Germany. Reviews reform efforts and attempts at problem resolution with specific emphasis on physics instruction. (ML)

Analysis of Microstrip Line Fed Patch Antenna for Wireless Communications

Directory of Open Access Journals (Sweden)

Singh Ashish

2017-11-01

Full Text Available In this paper, theoretical analysis of microstrip line fed rectangular patch antenna loaded with parasitic element and split-ring resonator is presented. The proposed antenna shows that the dualband operation depends on gap between parasitic element, split-ring resonator, length and width of microstrip line. It is found that antenna resonates at two distinct resonating modes i.e., 0.9 GHz and 1.8 GHz for lower and upper resonance frequencies respectively. The antenna shows dual frequency nature with frequency ratio 2.0. The characteristics of microstrip line fed rectangular patch antenna loaded with parasitic element and split-ring resonator antenna is compared with other prototype microstrip line fed antennas. Further, the theoretical results are compared with simulated and reported experimental results, they are in close agreement.

Letters of Stone. From Nazi Germany to South Africa. Steven Robins ...

African Journals Online (AJOL)

merely hint at the gruesome reality in Nazi Germany. With the hindsight granted to present-day readers, we know the fate that awaited these men and women as an elongated and agonising social death reached its culmination in systematic mass murder. In describing his journeys to Germany,. Poland, Israel and the United ...

Coal mining situation in the Federal Republic of Germany. Year 2016

International Nuclear Information System (INIS)

2017-01-01

The paper reports on the coal mining in the Federal Republic of Germany in the year 2016. Statistical data are presented for coal market, brown coal mining as well as the hard coal mining. These data consider the supply and demand of coal in Germany, and employees of the German coal industry.

Coal mining situation in the Federal Republic of Germany. Year 2015

International Nuclear Information System (INIS)

2016-01-01

The paper reports on the coal mining in the Federal Republic of Germany in the year 2015. Statistical data are presented for coal market, brown coal mining as well as the hard coal mining. These data consider the supply and demand of coal in Germany, and employees of the German coal industry.

Simulation of kefiran production of Lactobacillus kefiranofaciens JCM6985 in fed-batch reactor

Directory of Open Access Journals (Sweden)

Benjamas Cheirsilp

2006-09-01

Full Text Available Kinetics of kefiran production by Lactobacillus kefiranofaciens JCM6985 has been investigated. A mathematical model taking into account the mechanism of exopolysaccharides production has been developed. Experiments were carried out in batch mode in order to obtain kinetic model parameters that were further applied to simulate fed-batch processes. A simplification of parameter fitting was also introduced for complicated model. The fed-batch mode allows more flexibility in the control of the substrate concentration as well as product concentration in the culture medium. Based on the batch mathematical model, a fed-batch model was developed and simulations were done. Simulation study in fed-batch reactor resulted that substrate concentration should be controlled at 20 g L-1 to soften the product inhibition and also to stimulate utilization of substrate and its hydrolysate. From simulation results of different feeding techniques, it was found that constant feeding at 0.01 L h-1 was most practically effective feeding profile for exopolysaccharides production in fed-batch mode.

FEEDING FREQUENCY OF NILE TILAPIA FED RATIONS SUPPLEMENTED WITH AMINO ACIDS

Directory of Open Access Journals (Sweden)

EDUARDO ARRUDA TEIXEIRA LANNA

2016-01-01

Full Text Available The present study evaluated the feeding frequency of Nile tilapia (Oreochromis niloticus fed low-protein diets (29% crude protein supplemented with commercial amino acids (L-lysine-HCl, DL-methionine, and L-threonine. Sex-reversed Nile tilapia (240 of Thai origin, with initial body weight of 0.93 ± 0.03 g each, were allocated in a completely randomized design, to five groups with various feeding frequencies (2, 3, 4, 5, and 6 times a day. Six replications were conducted on separate experimental units comprising eight fishes each. The fish were maintained in 30 130-L aquariums, each equipped with individual water supply and controlled temperature and aeration. Fish were fed identical quantities among all treatments over a period of 30 days. Performance parameters, feed conversion efficiency, body composition, daily protein and fat deposition rates, and nitrogen retention efficiency were evaluated. Increased feeding frequency affected neither performance parameters nor body composition. Values for protein and fat deposition rates and nitrogen retention efficiency were significantly lower in fish fed twice daily than in those fed five times daily. Fish subjected to other feeding frequencies yielded intermediate values without any significant differences. The minimum feeding frequency of Nile tilapia fingerlings fed a low-protein ration supplemented with commercial amino acids is three times a day, owing to increased protein deposition rates and nitrogen retention efficiency.

54Mn absorption and excretion in rats fed soy protein and casein diets

International Nuclear Information System (INIS)

Lee, D.Y.; Johnson, P.E.

1989-01-01

Rats were fed diets containing either soy protein or casein and different levels of manganese, methionine, phytic acid, or arginine for 7 days and then fed test meals labeled with 2 microCi of 54Mn after an overnight fast. Retention of 54Mn in each rat was measured every other day for 21 days using a whole-body counter. Liver manganese was higher (P less than 0.0001) in soy protein-fed rats (8.8 micrograms/g) than in casein-fed rats (5.2 micrograms/g); manganese superoxide dismutase activity also was higher in soy protein-fed rats than in casein-fed rats (P less than 0.01). There was a significant interaction between manganese and protein which affected manganese absorption and biologic half-life of 54Mn. In a second experiment, rats fed soy protein-test meals retained more 54Mn (P less than 0.001) than casein-fed rats. Liver manganese (8.3 micrograms/g) in the soy protein group was also higher than that (5.7 micrograms/g) in the casein group (P less than 0.0001), but manganese superoxide dismutase activity was unaffected by protein. Supplementation with methionine increased 54Mn retention from both soy and casein diets (P less than 0.06); activity of manganese superoxide dismutase increased (P less than 0.05) but liver manganese did not change. The addition of arginine to casein diets had little effect on manganese bioavailability. Phytic acid affected neither manganese absorption nor biologic half-life in two experiments, but it depressed liver manganese in one experiment. These results suggest that neither arginine nor phytic acid was the component in soy protein which made manganese more available from soy protein diets than casein diets

Nutrient digestibility and mass balance in laying hens fed a commercial or acidifying diet.

Science.gov (United States)

Wu-Haan, W; Powers, W J; Angel, C R; Hale, C E; Applegate, T J

2007-04-01

The objectives of the current study were to evaluate the effect of an acidifying diet (gypsum) combined with zeolite and slightly reduced crude protein (R) vs. a control diet (C) on nutrient retention in laying hens and compare 3 approaches to estimating nutrient excretion from hens: 1) mass balance calculation (feed nutrients - egg nutrient), 2) use of an indigestible marker with analyzed feed and excreta nutrient content, and 3) an environmental chamber that allowed for capturing all excreted and volatilized nutrients. Hens (n = 640) were allocated randomly to 8 environmental chambers for 3-wk periods. Excreta samples were collected at the end of each trial to estimate apparent retention of N, S, P, and Ca. No diet effects on apparent retention of N were observed (53.44%, P > 0.05). Apparent retention of S, P, and Ca decreased in hens fed R diet (18.7, - 11.4, and 22.6%, respectively) compared with hens fed the C diet (40.7, 0.3, and 28.6%, respectively; P < 0.05). Total N excretion from hens fed the C and R diet was not different (1.16 g/hen/d); however, mass of chamber N remaining in excreta following the 3-wk period was less from hens fed the C diet (1.27 kg) than from hens fed the R diet (1.43 kg). Gaseous emissions of NH(3) over the 3-wk period from hens fed the C diet (0.74 kg per chamber) were greater than emissions from hens fed the R diet (0.45 kg). The 3-wk S excretion mass (estimated using the calculation, indigestible marker, and environmental chamber methods, respectively) was greater from hens fed the R diet (1.85, 1.54, and 1.27 kg, respectively) compared with hens fed the C diet (0.24, 0.20, and 0.14 kg, respectively). The 3-wk P excretion was similar between diets (0.68 kg). Results demonstrate that feeding the acidified diet resulted in decreased N emissions, but because of the acidulant fed, greatly increased S excretion and emissions.

Biological response of rats fed with tofu treated with high hydrostatic pressure.

Science.gov (United States)

Préstamo, G; Arroyo, G

2000-10-01

Emerging technologies for food preservation have arisen in recent years, such as high-pressure (HP) hydrostatic treatment, and the biological response for this kind of food preservation is not well-known. Forty female rats (six weeks old) were used in the experiment to evaluate the biological effects of HP treatment of tofu. The animals were divided into groups that were fed with tofu (untreated), tofu treated with HP, and conventional food (as control) for 28 days. The glucose level, mineral content (calcium, potassium, zinc, and magnesium), shinbone maximum shear force, weight of the body, and weight of organs (heart, liver, spleen, and kidneys) were analyzed. The biological response for the rats was that significant differences were found in the calcium amount determined on the serum of the rats fed with untreated tofu and those fed with tofu treated with HP, and the calcium amount was lower on the rats fed with tofu treated with HP. Also, there were significant differences in the weight of the liver, and it was lower in the rats fed with tofu treated with HP. It was quite remarkable how the weight of the body and organs were smaller in the rats fed with tofu in comparison to the weight of the control rats. In the other components assayed no significant differences were found. HP produces a potential effect on tofu as it is observed in the rats response to the tofu treated with HP.

Migración irregular de haitianos hacia república dominicana y sus implicaciones socio-económicas en el desarrollo de ambas naciones

OpenAIRE

Ovalles Mejía, José Manuel; Uribe Mendoza, Cristhian José

2017-01-01

84 páginas : gráficos. Esta investigación analiza la migración irregular de haitianos hacia la República Dominicana y sus implicaciones socio-económicas en el desarrollo de ambas naciones durante el período 2010-2015. Este tema reviste gran importancia en el entendido de que los dos países analizados, con condiciones económicas, políticas, sociales y culturales con marcadas diferencias, hoy día comparten y conviven en una misma isla a causa del fenómeno de la migración. Se hace una des...

Del idealismo al realismo relaciones entre España y Corea desde la Segunda República hasta la Guerra de Corea (1931-1953)

OpenAIRE

Choe, Hae Sung

2006-01-01

En las relaciones entre España y Corea hasta la entrada del siglo XX, predominaban un desinterés mutuo y escasos contactos. No obstante, llegó un nuevo período de atención sorprendente y de alto interés. El objetivo del presente trabajo es analizar y reconstruir las relaciones e influencias, imágenes y percepciones entre España y Corea durante dicho período comprendido entre la Segunda República y la Guerra de Corea (1931-1953), mediante la metodología interdisciplinar que proporcionan la his...

Educação escolar na primeira república: memória, história e perspectivas de pesquisa

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Alessandra Frota Martinez de Schueler

2009-01-01

Full Text Available O presente artigo desenvolve uma reflexão sobre a educação escolar, enfocando os debates, projetos e iniciativas voltadas para a disseminação da escola primária, no período da Primeira República (1889 a 1930, e problematizando a produção historiográfica sobre a educação republicana. Pretende-se contribuir para a abertura de um novo espectro de perguntas e problemas aos pesquisadores que se preocupam com a constituição da cultura escolar moderna e com os processos de socialização, transmissão, circulação, criação, apropriação e re (invenção culturais a partir da escola.

La integración en un sistema de bibliotecas de la Universidad de la República: una mirada desde las políticas educativas universitarias

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Isabel Madrid

2013-12-01

Full Text Available Se presenta una historia de los intentos de integración en un sistema de las bibliotecas de la Universidad de la República, con énfasis en el período que se inicia en 2003-2004, a partir de la conformación de la Subcomisión de Bibliotecas en el ámbito del Prorrectorado de Gestión Administrativa.Se intenta analizar el proceso en términos de políticas públicas de educación superior.

La cultura organizacional y la gestión del talento humano percibido por los trabajadores del Departamento de Comisiones del Congreso de la República

OpenAIRE

Ku Soria, Pamela Cinthya

2016-01-01

La investigación tuvo como objetivo general determinar la relación entre la cultura organizacional y la gestión del talento humano percibido por los trabajadores del Departamento de Comisiones del Congreso de la República del Perú. La investigación fue hipotética deductiva, descriptiva y correlacional, con diseño no experimental – transversal y enfoque cuantitativo. Se trabajó con una muestra de 132 trabajadores del Departamento de Comisiones de la institución. Para medir la...

The Effect of Rain-Fed and Supplementary Irrigation on the Yield ...

African Journals Online (AJOL)

The effect of rain-fed with rain-fed supplementary irrigation on yield and yield components of Maize (Zea mays L.) was carried out at Mekelle University main campus under Tigray region in Ethiopia. The experiment was laid out in a Randomized Complete Block Design (RCBD), and investigated in the early cropping season ...

Conference on hydrogen-energy in France and Germany

International Nuclear Information System (INIS)

Bodineau, Luc; Menzen, Georg; Arnold, Peter Erich; Mauberger, Pascal; Roentzsch, Lars; Poggi, Philippe; Gervais, Thierry; Schneider, Guenther; Colomar, David; Buenger, Ulrich; Nieder, Babette; Zimmer, Rene; Jeanne, Fabrice; Le Grand, Jean-Francois

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on hydrogen-energy in France and Germany. In the framework of this French-German exchange of experience, about 200 participants exchanged views on the different perspectives for use of hydrogen, in particular in transportation and energy storage applications. The technical production, transport and storage means were addressed too, as well as the technological models and the conditions for a large-scale industrial deployment. The economic prospects of hydrogen-energy in tomorrow's energy mix were also considered during the conference. This document brings together the available presentations (slides) made during this event: 1 - Hydrogen energy and Fuel Cells in France Today, and prospective (Luc Bodineau); 2 - The situation of energy Policy in Germany and the challenges for the Hydrogen Technology (Georg Menzen); 3 - Unlocking the Hydrogen Potential for Transport and Industry (Peter Erich Arnold); 4 - Hydrogen, a new energy for our planet - Hydrogen storage possibilities: example of solid storage (Pascal Mauberger); 5 - Innovative Materials and Manufacturing Technologies for H 2 Production and H 2 Storage (Lars Roentzsch); 6 - Scientific development and industrial strategy: experience feedback from the Myrte platform and energy transition-related perspectives (Philippe Poggi, Thierry Gervais); 7 - 'Power to Gas' - Important partner for renewables with big impact potential (Guenther Schneider) 8 - Developing a Hydrogen Infrastructure for Transport in France and Germany - A Comparison (David Colomar, Ulrich Buenger); 9 - H 2 and Fuel-Cells as Key Technologies for the Transition to Renewable energies - The example of Herten (Babette Nieder); 10 - Social acceptance of hydrogen mobility in Germany (Rene Zimmer); 11 - Hydrogen - A development opportunity for regions? (Fabrice Jeanne)

Comparisons in good and bad: criminality in Japan and Germany.

Science.gov (United States)

Kühne, H H

1994-12-16

In the field of criminological comparison, Japan and Germany are very suitable subjects. A nearly identical penal law and a social structure of highly developed industrial societies after a complete destruction at the end of World War War II give a good match. At first sight, Japan's crime rate is less than 1/4 of that in Germany. The impact of organised crime on the reduction of general crime is discussed.

Rumen volatile fatty acids and milk composition from cows fed hay, haylage, or urea-treated corn silage.

Science.gov (United States)

Schingoethe, D J; Voelker, H H; Beardsley, G L; Parsons, J G

1976-05-01

Alfalfa-brome hay, haylage, .5% urea-treated corn silage, or .5% urea plus 1% dried whey-treated corn silage was fed as the only forage to one of four groups of 10 lactating cows per group for a lactation trial of 10 wk. Rumen samples were collected via stomach tube 3 to 4 h after the morning feeding. The pH of the rumen samples from cows fed hay was higher than for cows fed haylage, urea-treated corn silage, and urea-whey corn silage, 6.69 versus 6.36, 6.40, and 6.50. Total volatile fatty acids and propionate were highest from cows fed urea-whey corn silage and were higher on all three fermented forages than cows fed hay. Acetate/propionate ratio was highest from cows fed hay and lowest from cows fed corn silages. Butyrate was highest from cows fed haylage or hay. Milk protein composition was not affected by ration although nonprotein nitrogen of milk was highest from cows fed the urea-treated corn silages. Oleic acid and total unsaturated fatty acids were lowest in milk fat from cows fed hay while palmitic acid was highest from cows fed hay and haylage. These results suggest that type of forage fed may cause small changes in rumen fermentation and in milk composition. The importance of these changes is unknown but may affect properties of dairy products produced from this milk.

Lymphogranuloma venereum in men screened for pharyngeal and rectal infection, Germany.

Science.gov (United States)

Haar, Karin; Dudareva-Vizule, Sandra; Wisplinghoff, Hilmar; Wisplinghoff, Fabian; Sailer, Andrea; Jansen, Klaus; Henrich, Birgit; Marcus, Ulrich

2013-03-01

To determine prevalence of lymphogranuloma venereum among men who have sex with men in Germany, we conducted a multicenter study during 2009-2010 and found high rates of rectal and pharyngeal infection in men positive for the causative agent, Chlamydia trachomatis. Many infections were asymptomatic. An adjusted C. trachomatis screening policy is justified in Germany.

Fed-batch CHO cell culture for lab-scale antibody production

DEFF Research Database (Denmark)

Fan, Yuzhou; Ley, Daniel; Andersen, Mikael Rørdam

2017-01-01

Fed-batch culture is the most commonly used upstream process in industry today for recombinant monoclonal antibody production using Chinese hamster ovary cells. Developing and optimizing this process in the lab is crucial for establishing process knowledge, which enable rapid and predictable tech......-transfer to manufacturing scale. In this chapter, we will describe stepwise how to carry out fed-batch CHO cell culture for lab-scale antibody production....

La República, la Guerra Civil Española y su impacto en la colectividad española de Valparaíso

Directory of Open Access Journals (Sweden)

Baldomero Estrada Turra

2013-07-01

Full Text Available Se analiza la evolución que tiene la colectividad española de Valparaíso durante la década de 1930 cuando España se ve afectada por la instauracion de la República y luego por la Guerra Civil. La ruptura que afectó a la comunidad española, como efecto de los acontecimientos de España, fue de una profundidad mayor que en otras ciudades del país y marcó su desarrollo institucional y comunitario por muchos años. Solo el paso de los años y los cambios generacionales permitieron superar las heridas del pasado.

Identity construction: A comparison between Turkish Muslims in Australia and Germany

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Tuba Boz

2012-10-01

Full Text Available The essentialization of identity coupled with its confused association with loyalty has ensured that issues related to identity are at the forefront of politics, and are used as a platform to generate moral panics which are fuelled by the mass corporate media. Different socio-political contexts affect identity construction among Turkish Muslims in Germany and Australia. Based on qualitative interview data collected in 2008 and 2009 in Germany and Australia, this paper examines the circumstances that influence the self-conception of the Turkish Muslims in both countries. The different political and demographic circumstances of each country are described and their impact on identity formation taken into account. Then we use labeling theory, that is, differences in the language, concepts and official descriptions used by the powerful in each society to label minority groups (Akers 1999, in order to examine the impact of top-down government policies on identity construction among Turkish communities in Australia and Germany - a major example of this being the contrast between Australia's multicultural policies with Germany's assimilationist integration policies.

Oligosaccharides in feces of breast- and formula-fed babies.

Science.gov (United States)

Albrecht, Simone; Schols, Henk A; van Zoeren, Diny; van Lingen, Richard A; Groot Jebbink, Liesbeth J M; van den Heuvel, Ellen G H M; Voragen, Alphons G J; Gruppen, Harry

2011-10-18

So far, little is known on the fate of oligosaccharides in the colon of breast- and formula-fed babies. Using capillary electrophoresis with laser induced fluorescence detector coupled to a mass spectrometer (CE-LIF-MS(n)), we studied the fecal oligosaccharide profiles of 27 two-month-old breast-, formula- and mixed-fed preterm babies. The interpretation of the complex oligosaccharide profiles was facilitated by beforehand clustering the CE-LIF data points by agglomerative hierarchical clustering (AHC). In the feces of breast-fed babies, characteristic human milk oligosaccharide (HMO) profiles, showing genetic fingerprints known for human milk of secretors and non-secretors, were recognized. Alternatively, advanced degradation and bioconversion of HMOs, resulting in an accumulation of acidic HMOs or HMO bioconversion products was observed. Independent of the prebiotic supplementation of the formula with galactooligosaccharides (GOS) at the level used, similar oligosaccharide profiles of low peak abundance were obtained for formula-fed babies. Feeding influences the presence of diet-related oligosaccharides in baby feces and gastrointestinal adaptation plays an important role herein. Four fecal oligosaccharides, characterized as HexNAc-Hex-Hex, Hex-[Fuc]-HexNAc-Hex, HexNAc-[Fuc]-Hex-Hex and HexNAc-[Fuc]-Hex-HexNAc-Hex-Hex, highlighted an active gastrointestinal metabolization of the feeding-related oligosaccharides. Their presence was linked to the gastrointestinal mucus layer and the blood-group determinant oligosaccharides therein, which are characteristic for the host's genotype. Copyright © 2011 Elsevier Ltd. All rights reserved.

TopFed: TCGA tailored federated query processing and linking to LOD.

Science.gov (United States)

Saleem, Muhammad; Padmanabhuni, Shanmukha S; Ngomo, Axel-Cyrille Ngonga; Iqbal, Aftab; Almeida, Jonas S; Decker, Stefan; Deus, Helena F

2014-01-01

The Cancer Genome Atlas (TCGA) is a multidisciplinary, multi-institutional effort to catalogue genetic mutations responsible for cancer using genome analysis techniques. One of the aims of this project is to create a comprehensive and open repository of cancer related molecular analysis, to be exploited by bioinformaticians towards advancing cancer knowledge. However, devising bioinformatics applications to analyse such large dataset is still challenging, as it often requires downloading large archives and parsing the relevant text files. Therefore, it is making it difficult to enable virtual data integration in order to collect the critical co-variates necessary for analysis. We address these issues by transforming the TCGA data into the Semantic Web standard Resource Description Format (RDF), link it to relevant datasets in the Linked Open Data (LOD) cloud and further propose an efficient data distribution strategy to host the resulting 20.4 billion triples data via several SPARQL endpoints. Having the TCGA data distributed across multiple SPARQL endpoints, we enable biomedical scientists to query and retrieve information from these SPARQL endpoints by proposing a TCGA tailored federated SPARQL query processing engine named TopFed. We compare TopFed with a well established federation engine FedX in terms of source selection and query execution time by using 10 different federated SPARQL queries with varying requirements. Our evaluation results show that TopFed selects on average less than half of the sources (with 100% recall) with query execution time equal to one third to that of FedX. With TopFed, we aim to offer biomedical scientists a single-point-of-access through which distributed TCGA data can be accessed in unison. We believe the proposed system can greatly help researchers in the biomedical domain to carry out their research effectively with TCGA as the amount and diversity of data exceeds the ability of local resources to handle its retrieval and

Dietary inclusion of direct fed microbe on the growth performance of ...

African Journals Online (AJOL)

The birds were obtained from a reputable hatchery and randomly assigned to four dietary treatments, each with three replicate of ten birds. ... The results show that the growth performance of the broiler chicken fed diet containing different level of direct fed microbes did not differ significantly (P>0.05) in initial weight, final ...

West Germany: Federal Structure, Political Influence.

Science.gov (United States)

Toogood, Alex

1978-01-01

Describes the organizational structure of the broadcasting industry in West Germany which is unique because of the federal, public, and political elements involved. Special problems that arise from this framework are discussed, including financing, programing, creative vs technical advances, concepts of production values, and political balance.…

Distance Education at Conventional Universities in Germany

Directory of Open Access Journals (Sweden)

Hans-Henning Kappel

2002-01-01

Full Text Available Germany’s educational system has undergone a series of transformations during the last 40 years. In recent years, marked increases in enrolment have occurred. In response, admission requirements have been relaxed and new universities have been established.Academic distance education in the former Federal Republic of Germany (West Germany was ushered in by the educational radio broadcasts around the end of the 1960s. Aside from the formation of the FernUniversität (Open University in West Germany in 1975, there were significant developments in distance education occurring at the major universities in the German Democratic Republic (East Germany. After German reunification in 1990, the new unitary state launched programs to advance the development of distance education programs at conventional universities.Germany’s campus-based universities (Präsenzuniversitäten created various entities, including central units and consortia of universities to design and market distance education programs. Hybridisation provides the necessary prerequisites for dual mode delivery, such as basic and continuing education programs, as well as for the combination of distance and campus-based education (Präsenzstudium. Hybridisation also has also opened the door for the creation of new programs.Following an initial phase in which distance education research is expected to centralize a trend towards decentralisation is likely to follow. The German Association for Distance Education (AG-F offers a viable research network in distance education. Two dual mode case studies are also be surveyed: The Master of Arts degree, offered by the University of Koblenz-Landau, with Library Science as the second major, and the University of Kaiserslautern, where basic education will continue to be captured within the domain of the Präsenzstudium or campus-based education.The area in which distance education is flourishing most is within the field of academic continuing

Dental hygiene education in Germany: Between economics and emotions.

Science.gov (United States)

Offermanns, B; Petersilka, G J

2017-08-30

To date, there is still no IFDH approved dental hygienist (DH) education model in Germany. Nevertheless, opportunities to complete vocational DH education courses have substantially increased within the last two decades. However, the content and quality of these courses vary greatly and are difficult to survey. The purpose of this article therefore was to present an overview of the education programmes offered in Germany as of March 2017. A formal request was sent to all education establishments for details of such courses, and a systematic internet search was performed covering the DH education topic in Germany. Ten vocational education programmes were found, most of them organized by local dental chambers. One private provider offers a Bachelor Degree in Dental Hygiene on completion of a course which runs over 2 or 3 ys. Details of contents, objectives and concise ratings or comparisons of the various courses are scarce, although in principle all should meet the same quality standards. For dental hygiene students, patients and dentists, it is hard and unsatisfactory to get a clear overview of the types and the quality of DH education which can be achieved in Germany. A solution for this dilemma would appear to be essential. However, due to the peculiarities of German legislation as well as the complex sphere of vested interests, it is impossible to predict if or when the situation will change for the better. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Aquifer thermal energy stores in Germany

International Nuclear Information System (INIS)

Kabus, F.; Seibt, P.; Poppei, J.

2000-01-01

This paper describes the state of essential demonstration projects of heat and cold storage in aquifers in Germany. Into the energy supply system of the buildings of the German Parliament in Berlin, there are integrated both a deep brine-bearing aquifer for the seasonal storage of waste heat from power and heat cogeneration and a shallow-freshwater bearing aquifer for cold storage. In Neubrandenburg, a geothermal heating plant which uses a 1.200 m deep aquifer is being retrofitted into an aquifer heat storage system which can be charged with the waste heat from a gas and steam cogeneration plant. The first centralised solar heating plant including an aquifer thermal energy store in Germany was constructed in Rostock. Solar collectors with a total area of 1000m 2 serve for the heating of a complex of buildings with 108 flats. A shallow freshwater-bearing aquifer is used for thermal energy storage. (Authors)

Germany, Austria and dissolution of Yugoslavia

Directory of Open Access Journals (Sweden)

Vuković Slobodan V.

2001-01-01

Full Text Available The article deals with one of the causes of dissolution/breakdown of Yugoslavia. The author first analyses writing of German and Austrian press which has, at the very beginning of the crisis, taken a strong anti-Serb standing, as in 1914 and 1941. Author then analyses the reasons that led Austrian and German diplomacy and governments to actively forging the crisis and then breaking down a sovereign country. Those reasons could be summarized as follows: German and Austrian revenge for two wars lost in these territories; improvement of conditions for fulfillment of old German dream to advance toward Middle East; in order to become a world power Germany 'had to' to annul some of the consequences of the First and Second World War on the symbolic level and acquire a possibility to test its powers, and breaking down Yugoslavia, with help of its internal allies Germany broke down its army without military engagement and removed an obstacle for advancement towards East.

Tissue deposition of polychlorinated biphenyls in cats fed Atlantic Ocean bluefish.

Science.gov (United States)

Carbone, L G; Alo, D K; Scarlett, J M; Gutenmann, W H; Lisk, D J

1991-07-01

Bluefish (Pomatomus saltatrix), a very popular marine sport fish caught in Atlantic coastal waters, contain significant levels of polychlorinated biphenyls (PCBs). Since fish can be an appreciable portion of human and feline diets, a feeding study was conducted with cats fed exclusively bluefish for 86 days with determination of tissue concentrations of PCBs. The concentrations of PCBs in brain, liver, and fat were significantly higher (p = 0.01) in the fish-fed cats than in the control group using the Wilcoxon rank sum test. The highest PCB levels were in fat, the median concentrations being 48 and 0.61 ppm (dry weight) in the fish-fed and control cats, respectively. The significance of the results is discussed.

Extent and application of ICU diaries in Germany in 2014

DEFF Research Database (Denmark)

Nydahl, Peter; Knueck, Dirk; Egerod, Ingrid

2015-01-01

in keeping ICU diaries. CONCLUSION: Six years after the introduction of ICU diaries, ICU nurses in Germany are becoming familiar with the concept. Nursing shortage and bureaucratic challenges have impeded the process of implementation, but the adaption of ICU diaries to German conditions appears......, newsletters, newspapers, lectures and publications in German nursing journals. AIM: The aim of the study was to update our knowledge of the extent and application of ICU diaries in Germany in 2014. DESIGN: The study had a prospective mixed methods multicenter design. METHOD: All 152 ICUs in the two German...... of Germany had implemented diaries and three units were planning to do so. Interviews were conducted with nurses at 14 selected ICUs. Informants reported successful adaption of the diary concept to their culture, but variability in application. No units were identified where all nursing staff participated...

"Great Technology, Football and...": Malaysian Language Learners' Stereotypes about Germany

Directory of Open Access Journals (Sweden)

Larisa Nikitina

2014-12-01

Full Text Available This study focuses on stereotypes about Germany, its culture and people, held by learners of German in a big public university in Malaysia. It examines not only the stereotypical representations of the target language country but also assesses its favourability and salience, which has not been done previously. The findings revealed that the students' stereotypes about Germany were varied and diverse. Also, they were overwhelmingly positive. The top three salient categories of images about Germany were related to technology, famous personalities - for the most part football players and scientists - and cars. The findings also indicated that very few references had been made to German culture and to its great cultural figures. The results of the present study suggest that students could benefit from a wider and deeper exposure to German culture in the language classroom.

ELEMENTS OF NEOCONSERVATISM IN THE CONTEMPORARY POLITICAL SOCIETY IN GERMANY

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М С Ладыгин

2017-12-01

Full Text Available The article is devoted to the phenomenon of strengthening neoconservative sentiments, i.e. neocon actors, in Germany. The paper analyzes the aims of three neoconservative actors in Germany: the party Alternative for Germany, the social movement PEGIDA and the “Identitarian movement”. It is found that all three parties have similar aims and their cooperation could lead to a serious strengthening of neocon positions both in society and on the political landscape. One of the conclusions of the article at hand is that it is too early to judge the party's ability to work as an established party. This conclusion is accompanied with the fact that the majority of those who voted for AfG were so called “protest voters”, hence they may prevent the return of the party in the next elections to the Bundestag.

The future of nuclear power in Germany

International Nuclear Information System (INIS)

Holzer, J.

1993-01-01

The future of nuclear power in Germany is not only a matter of technology, economy and ecology but, above all, a matter of political leadership, the quality of interaction of all groups of society, the need to take ideology out of politico-economico-technical matters, and of firmly standing up for a style of democracy in which majorities, not minorities, decide. The power economy is agreed that nuclear power is indispensable in a powerful electricity supply scheme. These should be the criteria to be met by an energy consensus: No nuclear plants should be sacrificed by being shut down before the end of their technical and economic service life; spent fuel and waste management in Germany should be secured with sufficient interim storage and repository storage capacities. (orig.) [de

Traffic Mortality in Germany Before, During, and After Reunification

OpenAIRE

Winston, Flaura K.; Menon, Rajiv; Moll, Elisa K.; Arbogast, Kristy B.; Baker, Susan P.

1999-01-01

Following the fall of the Berlin Wall in late 1989, the combination of sudden wealth, sudden access to cars, and a flood of new young drivers had disastrous effects on East Germans. While motor vehicle occupant death rates decreased in West Germany, motor vehicle occupant death rates in East Germany surged upward. Between 1989 and 1991, the death rate increased for all age groups but was greatest for 18–20 year olds (from 5 to 54 deaths/100,000) and 21–24 year olds (from 5 to 44). Fatality ra...

Unlimited - nuclear liabilities in the Federal Republic of Germany

International Nuclear Information System (INIS)

Arendt, W.

1986-01-01

Unlimited nuclear liabilities as in force in the Federal Republic of Germany go beyond the international rules of the Paris liability agreement. The unlimited liability mainly roots in the positive operational experiences and safety balance of the 20 nuclear power plants which meanwhile are in operation in the Federal Republic of Germany. Nuclear liabilities must not be confounded with scepticism as to the utilization of nuclear power. Extraordinary requirements of that kind should rather be reflecting responsibility and clear ideas and notions of the advantages and risks of nuclear energy. (HSCH) [de

Gastrointestinal absorption and retention of neptunium by fasted and fed mice

International Nuclear Information System (INIS)

Larsen, R.P.; Bhattacharyya, M.H.; Oldham, R.D.; Moretti, E.S.

1982-01-01

The retention of neptunium in liver and bone subsequent to its gastrointestinal absorption has been determined in both fasted and fed mice. The values obtained for fractional retention were 3 x 10 - 3 and 1 x 10 - 4 , respectively, and are within a factor of two the same as those for plutonium in fasted and fed mice

[Quality of health care in Germany. A six-country comparison].

Science.gov (United States)

Sawicki, Peter T

2005-11-15

Sicker adults in Germany suffer many of the same issues and concerns as do sicker adults in Australia, Canada, New Zealand, the United Kingdom, and the USA. However, quality of care in sicker adults in Germany stands out from the other countries in a few key areas: 1. DISSATISFACTION WITH THE HEALTH CARE SYSTEM: Almost one in three sicker adults in Germany feels that their health care system should be completely rebuilt. This is comparable to the USA and Australia and higher than in New Zealand, Canada, and the UK. 2. STRENGTHS AND WEAKNESSES IN COORDINATION OF CARE: On the plus side, Germany is doing better than most countries to insure that needed information is available at the time of a patient''s scheduled appointment. Also, sicker adults in Germany are more likely than in other countries to have a long-term relationship with their primary care physician and receive less often conflicting informations. However, Germany stands out in the proportion of sicker adults who feel that their doctors have ordered a medical test that they thought was unnecessary because it had already been done. 3. COMPARATIVELY EASY ACCESS TO OUTPATIENT, SPECIALTY AND EMERGENCY CARE: Though substantial minorities of sicker adults in Germany struggle with access to care as compared to other countries, they find it easier to get after hours care and have the shortest waits to see a doctor, to see a specialist, to have nonemergency surgery, and to be seen in the emergency room. Along with the USA, German respondents are most satisfied with the amount of choice they have in a surgeon 4. COMMUNICATION ABOUT RISKS DURING HOSPITALIZATIONS: Hospitalized sicker adults in Germany are more likely than those in other countries to have the risks of their treatment explained to some extent prior to the procedure. However, German patients are less likely to have the risks of their treatment fully explained than those in other countries. German patients who were given new medications were more likely

Cost-effectiveness and incidence of renewable energy promotion in Germany

OpenAIRE

Böhringer, Christoph; Landis, Florian; Tovar Reaños, Miguel Angel

2017-01-01

Over the last decade Germany has boosted renewable energy in power production by means of massive subsidies. The flip side are very high electricity prices which raises concerns that the transition cost towards a renewable energy system will be mainly borne by poor households. In this paper, we combine computable general equilibrium and microsimulation analysis to investigate the cost-effectiveness and incidence of Germany's renewable energy promotion. We find that the regressive effects of r...

Les revistes bilingües a la Tortosa de la II República

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M. Carme Gombau Domingo

2016-06-01

Full Text Available En l’àmbit de la premsa tortosina en català del primer terç del segle xx es donen dues actituds lingüístiques: la fabriana i la tortosinista. La primera, partidària del model de llengua de l’IEC, era minoritària als anys vint però es generalitza a partir dels anys trenta (La Veu de Tortosa, La Veu Comarcal, Ara, Acció, Vida Tortosina i Lluita; mentre que el tortosinisme, que es correspon amb una ideologia cada cop més localista i que eleva el «parlar tortosí» a la categoria de llengua, queda reduït durant la II República a tres revistes bilingües: La Zuda, Germanor i La Santa Cinta. There were two linguistic actitudes in the tortosine press of the first third in the 20th century: the fabriana amb the tortosinista. The fabriana, in favour of the IEC linguistic model, was in minority during the 20’s, but it became widespread from the 30’s (La Veu de Tortosa, La Veu Comarcal, Ara, Acció, Vida Tortosina i Lluita. The second, the tortosinista, had a local ideology and compared the tortosinisme talk as a complet language, but it was reduced during the ii Republic to three magazines: La Zuda, Germanor i La Santa Cinta.

Sistema de salud de República Dominicana The health system of Dominican Republic

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Magdalena Rathe

2011-01-01

Full Text Available En este trabajo se describen las condiciones de salud de la República Dominicana y, con mayor detalle, el sistema de salud dominicano, incluyendo su estructura y cobertura, sus fuentes de financiamiento, el gasto en salud, los recursos físicos, materiales y humanos de los que dispone, las tareas de rectoría que desarrolla el Ministerio de Salud Pública y la generación de información. También se discuten la participación de los usuarios en la operación y evaluación del sistema de salud y las más recientes innovaciones implementadas, dentro de las que destacan la nueva Ley General de Salud, la nueva Ley de Seguridad Social y el Plan Decenal de Salud.This paper describes the health conditions in Dominican Republic and the characteristics of the Dominican health system, including its structure and coverage, its financial sources, the health expenditure, the physical, material and human resources available, the stewardship functions developed by the Ministry of Public Health and the generation of health information. The participation of health care users in the operation and evaluation of the system and the most recent policy innovations, including the new General Health Law, the new Social Security Law and the Decennial Health Plan are also discussed.

Representações cômicas da República no contexto do Getulismo

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Elio Chaves Flores

2001-01-01

Full Text Available Neste artigo analiso as representações cômicas e discursivas da República e a trajetória política de Getúlio Vargas, a partir de uma narrativa que se assenta no método regressivo. Para isso, trabalhei com uma série de caricaturas publicadas em jornais e revistas na duração entre 1930 e 1954, confrontando a intertextualidade dessas imagens com alguns discursos satíricos e irônicos produzidos por memorialistas. Procuro demonstrar que há semelhança entre a inversão humorística e a textualidade da memória, quando inventam a respeito de seu tempo e dos outros imagens verossímeis.This article analyses the comic and discursive representations of the Brazilian Republic and Getúlio Vargas’ political career, starting from a narrative constructed in the regressive method. For that, I worked with a series of cartoons published in newspapers and magazines in the span of time between 1954 and 1930, matching the intertextuality of these images with some of the satiric and ironic speeches produced by witnesses. It is demonstrated there is likeness between the comic inversion and the textuality of the memory, when they invent concerning their time and other ones, the verisimilitude of the images.

Spirulina vesicolor Improves Insulin Sensitivity and Attenuates Hyperglycemia-Mediated Oxidative Stress in Fructose-Fed Rats

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Walaa Hozayen

2016-03-01

Full Text Available Aim: The current study aimed to investigate the anti-hyperglycemic, anti-hyperlipidemic and insulin sensitizing effects of the cyanobacterium Spirulina vesicolor extract in fructose-fed rats. Materials and Methods: Rats were fed 30% fructose solution in drinking water for 4 weeks. Animals exhibited hyperglycemia and hyperinsulinemia were selected for further investigations. Diabetic and control rats were orally supplemented with 50 mg/kg body weight S. vesicolor extract for 4 weeks. Results: At the end of 8 weeks, fructose-fed rats showed significant increase in serum glucose, insulin, cholesterol, triglycerides, cardiovascular risk indices and insulin resistance. Treatment of the fructose-fed rats with S. vesicolor extract improved this metabolic profile. Fructose feeding produced a significant increase in serum tumor necrosis factor alpha (TNF-α and a decrease in adiponectin levels. In addition, fructose-fed rats exhibited a significant increase in liver, kidney and heart lipid peroxidation levels, and declined antioxidant defenses. Supplementation of the fructose-fed rats with S. vesicolor extract reversed these alterations. Conclusion: S. vesicolor attenuates hyperglycemia-mediated oxidative stress and inflammation, and is thus effective in improving insulin sensitivity in fructose-fed rats. [J Complement Med Res 2016; 5(1.000: 57-64

Recursos administrativos en materia de propiedad industrial en la República Argentina, 2001 - 2012 : análisis estadístico, encuadre legal y criterios de resolución

OpenAIRE

Siniscalchi, Mariana

2014-01-01

La presente tesis por objetivo analizar las particularidades de los recursos administrativos interpuestos entre los años 2001 y 2012 contra actos dictados por el Instituto Nacional de la Propiedad Industrial (INPI) de la República Argentina en solicitudes de derechos de propiedad industrial: marcas, patentes de invención, modelos de utilidad, modelos y diseños industriales; y en solicitudes de registro de contratos de transferencia de tecnología.

The energy supply situation in Germany

International Nuclear Information System (INIS)

Lederer, P.

2007-01-01

The focus is on 4 energy supply issues of decisive relevance to energy supply in Germany, but also in other countries in Europe and worldwide: (1) How will the global energy situation develop? (2) What is the organization, and the development, of the market in which we are doing business? (3) What are the challenges facing the power industry in view of a threatening climate change? (4) Against this backdrop, how do we design the energy mix of the future? Analysis of these 4 points shows that, for a foreseeable time, all types of energy generation are necessary if Germany and Europe are to be supplied energy efficiently, securely, and in a way not polluting the environment. Hence, these concrete conclusions can be drawn: (1) We need more renewable energies in Germany, in Europe, and worldwide. (2) We need the development of 700 C coalfired power plant technology in order to first advance the development of CCS (carbon capture and storage) technology and thus minimize CO 2 emissions from fossil-fired power plants. (3) We need increases in energy efficiency which help us satisfy the steadily growing need for energy with dwindling fossil resources. (4) We need nuclear power because of its ability to produce baseload electricity free from CO 2 . For nuclear power, it is now important that politics and the power industry jointly find ways and means to reassess, in an unbiased way, the plant operating lives laid down in the current Atomic Energy Act. This is required, inter alia, because of the challenges in climate policy and because of global economic boundary conditions. (orig.)

An ecological tax reform in Germany

International Nuclear Information System (INIS)

Bakker, L.; Bleijenberg, A.N.

1992-01-01

This study, being a part of the large research program 'External Effects of Energy Procurement' and coordinated by PROGNOS, concerns the distributional and macro-economic effects of the internalization of the external effects of the energy supply by means of an ecological tax reform. The PROGNOS study is focused on the costs and effects of energy production, procurement and consumption (in Germany), that are not taken care of by the market. Here a rough estimate is given of the macro-economic consequence and the distributional effects for the industrial sector and households in (West) Germany of an energy tax of which the revenues are 'reinjected' into the economy, mainly by lowering the financial burden on labour. First a description is given of the starting points of the study and the form of the energy tax. Subsequently attention is paid to the macro-economic effects, the sectoral effects, and the effects on the distribution of incomes for households. The model calculations for Western Germany and the Netherlands confirm the expectation that an ecological tax reform leads to the combined realization of employment and environmental objectives. Shifts in the sectoral structure may occur. Energy intensive branches of industry will have to give up a part of their market share in favour of labour-intensive sectors. The results also illustrate that there are several possibilities to prevent a change in the collective burden of regular expenses as a result of a tax or levy on energy, and that the effects of a fuel tax on the income distribution can be corrected. 5 figs., 19 tabs., 5 apps., 15 refs

La "república posible" y sus problemas en Argentina: Normalistas e industriales debaten el plan educativo alberdiano de las dos gestiones presidenciales de Julio Argentino Roca (1880-1886 y 1898-1901 The "Possible Republic" and its Problems in Argentina: Student Teachers and Industrialists Debate the Alberdian Educational Plan of the Two Administrations of President Julio Argentino Roca (1880-1886 and 1898-1901

Directory of Open Access Journals (Sweden)

Alejandro Herrero

2011-08-01

Full Text Available Julio Argentino Roca, en sus dos presidencias a fines del siglo XIX, se adhiere al programa alberdiano de la república posible en Argentina. Intenta cambiar el sistema educativo que se opone a la república de habitantes productores de riqueza y, finalmente, se encuentra con algo peor: no sólo fracasa en este intento, sino que advierte en la misma contienda verbal que el mismo programa de la república posible es cuestionado por diferentes actores. En este artículo se estudia, como una primera aproximación al tema, a los normalistas y a los industriales, ya que parte del normalismo y de la corporación industrial apoyan decididamente la propuesta educativa alberdiana de Roca, sin embargo, cuestionan la república posible y manifiestan que se debe avanzar hacia una república de ciudadanos.During his two administrations in the late 19th century, Julio Argentino Roca adhered to Alberdi's program of the possible republic in Argentina. He attempted to change the education system that opposed the republic of inhabitants that created wealth and eventually discovered something worse: not only did he fail in this attempt, but he noticed, during the same verbal competition, that the program of the possible republic was questioned by different actors. As an initial approach to the topic, this article examines student teachers and industrialists, since a section of student teachers and the industrial Corporation determinedly supported Rocas Alberdian educational proposal. Nevertheless, they questioned the possible republic, adding that it should advance towards a republic of citizens.

FED firmware interface testing with pixel phase 1 emulator

CERN Document Server

Kilpatrick, Matthew

2017-01-01

A hardware emulation of the CMS pixel detector phase 1 upgrade front-end electronics has been developed to test and validate the architecture of the back-end electronics (FED) firmware. The emulation is implemented on a Virtex 6 FPGA on the CERN GLIB uTCA platform, utilizing an 8-way SFP FPGA Mezzanine Card to drive compatible optical transmitters to the back-end electronics at 400 bps. The firmware emulates the complex functions of the phase 1 pixel readout chips (PSI46digv2 and PROC600) and token bit manager ASICs and allows for possible abnormalities that can occur in the output data stream. The emulation implements both fixed data patterns that are used as test vectors and realistic simulated data to drive the readout of the FED at the expected data and trigger rates. Testing software was developed to control the emulator and verify correct transmission of data and exception handling in the FED. An installation has been integrated into the pixel DAQ test system at CMS to be used for fast validation of F...

FED firmware interface testing with pixel phase 1 emulator

CERN Document Server

Kilpatrick, Matthew

2018-01-01

A hardware emulation of the CMS pixel detector phase 1 upgrade front-end electronics has been developed to test and validate the architecture of the back-end electronics (FED) firmware. The emulation is implemented on a Virtex 6 FPGA on the CERN GLIB uTCA platform, utilizing an 8-way SFP FPGA Mezzanine Card to drive compatible optical transmitters to the back-end electronics at 400 bps. The firmware emulates the complex functions of the phase 1 pixel readout chips (PSI46digv2 and PROC600) and token bit manager ASICs and allows for possible abnormalities that can occur in the output data stream. The emulation implements both fixed data patterns that are used as test vectors and realistic simulated data to drive the readout of the FED at the expected data and trigger rates. Testing software was developed to control the emulator and verify correct transmission of data and exception handling in the FED. An installation has been integrated into the pixel DAQ test system at CMS to be used for fast validation of F...

Lambs Fed Fresh Winter Forage Rape (Brassica napus L.) Emit Less Methane than Those Fed Perennial Ryegrass (Lolium perenne L.), and Possible Mechanisms behind the Difference

Science.gov (United States)

Sun, Xuezhao; Henderson, Gemma; Cox, Faith; Molano, German; Harrison, Scott J.; Luo, Dongwen; Janssen, Peter H.; Pacheco, David

2015-01-01

The objectives of this study were to examine long-term effects of feeding forage rape (Brassica napus L.) on methane yields (g methane per kg of feed dry matter intake), and to propose mechanisms that may be responsible for lower emissions from lambs fed forage rape compared to perennial ryegrass (Lolium perenne L.). The lambs were fed fresh winter forage rape or ryegrass as their sole diet for 15 weeks. Methane yields were measured using open circuit respiration chambers, and were 22-30% smaller from forage rape than from ryegrass (averages of 13.6 g versus 19.5 g after 7 weeks, and 17.8 g versus 22.9 g after 15 weeks). The difference therefore persisted consistently for at least 3 months. The smaller methane yields from forage rape were not related to nitrate or sulfate in the feed, which might act as alternative electron acceptors, or to the levels of the potential inhibitors glucosinolates and S-methyl L-cysteine sulfoxide. Ruminal microbial communities in forage rape-fed lambs were different from those in ryegrass-fed lambs, with greater proportions of potentially propionate-forming bacteria, and were consistent with less hydrogen and hence less methane being produced during fermentation. The molar proportions of ruminal acetate were smaller and those of propionate were greater in forage rape-fed lambs, consistent with the larger propionate-forming populations and less hydrogen production. Forage rape contained more readily fermentable carbohydrates and less structural carbohydrates than ryegrass, and was more rapidly degraded in the rumen, which might favour this fermentation profile. The ruminal pH was lower in forage rape-fed lambs, which might inhibit methanogenic activity, shifting the rumen fermentation to more propionate and less hydrogen and methane. The significance of these two mechanisms remains to be investigated. The results suggest that forage rape is a potential methane mitigation tool in pastoral-based sheep production systems. PMID:25803688

Transpondo muros: Escritas da violência na República Democrática Alemã

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Elcio Loureiro Cornelsen

2009-06-01

Full Text Available O objetivo do presente artigo é esboçar, a partir da interpretação das obras “Zeit-Zeugen”. Inhaftiert in Berlin-Hohenschönhausen (1996, organizada por Gabriele Camphausen, Folterzelle 36 Berlin-Pankow. Erlebnisbericht einer Stasihaft (1993, de Timo Zilli, Ein guter Kampf. Fakten, Daten, Erinnerungen 1945-1954 (1998 do político Ewald Ernst, Die Stasi war mein Eckermann: oder mein Leben mit der Wanze (1991, do escritor Erich Loest, e Geboren am 13. August. Der Sozialismus und ich (2004, do jornalista Jens Bisky, um breve estudo sobre as diversas formas e fases da violência enquanto instrumento de poder, praticada pelo Estado do SED na República Democrática Alemã nos 40 anos de sua existência, e discutir especialmente alguns aspectos teóricos sobre o conceito de “literatura de testemunho”. Os cinco relatos analisados, de caráter memorialista e autobiográfico, se pautam por um tom decididamente crítico frente aos desmandos num Estado totalitário. “Transpor muros” nos 20 anos após a Queda do Muro de Berlim, desse ponto de vista, implica um olhar memorialista de denúncia contra o esquecimento frente a um passado traumático.

Growth, Feed Utilization and Blood Metabolic Responses to Different Amylose-amylopectin Ratio Fed Diets in Tilapia (

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Meng-Yao Chen

2013-08-01

Full Text Available A feeding trial was conducted in tilapia to determine the growth performance, nutrient digestibility, digestive enzymes, and postprandial blood metabolites in response to different dietary amylose-amylopectin ratios. Five isonitrogenous and isolipidic diets containing an equal starch level with different amylose-amylopectin ratios of 0.11 (diet 1, 0.24 (diet 2, 0.47 (diet 3, 0.76 (diet 4 and 0.98 (diet 5 were formulated using high-amylose corn starch (as the amylose source and waxy rice (as the amylopectin source. Each diet was hand-fed to six tanks of 15 fish each, three times a day over a 6-wk period. After the growth trial, a postprandial blood metabolic test was carried out. Fish fed diet 2 exhibited the highest percent weight gain and feed efficiency and protein efficiency ratio, whereas fish fed with diet 5 showed the lowest growth and feed utilization among treatments. The digestibility for starch in fish fed diet 1 and 2 was higher than those in fish fed with other diets (p<0.05. The highest activities for protease, lipase and amylase were found in fish fed the diet 2, diet 1, and diet 1 respectively among dietary treatments, while the lowest values for these indexes were observed in fish fed the diet 3, diet 5 and diet 4, respectively. The liver glycogen concentrations in fish fed diets 4 and 5 were found higher than in fish fed other diets (p<0.05. The feeding rate, hepatosomatic index, condition factor, and plasma parmeters (glucose, triglyceride, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol did not differ across treatments. In terms of postprandial blood responses, peak blood glucose and triglycerides were lower after 3 or 6 h in the fish fed with diets 3–5 than in the fish fed diet 1, but delayed peak blood total amino acid time was observed in fish fed with the diets 1 or 2. The lowest peak values for each of the three blood metabolites were observed in fish fed diet 5. The

Aseptic meningitis in Germany associated with echovirus type 13

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Schreier Eckart

2001-09-01

Full Text Available Abstract Background Echoviruses are the commonest cause of aseptic meningitis. Echovirus type 13 which has not been isolated in Germany over a long period of time was the predominant enterovirus serotype associated with different local outbreaks of aseptic meningitis in Germany in 2000. Methods Virus isolation was performed from cerebrospinal fluid and stools. In order to study the genetic relationship of echovirus type 13 isolates, sequence analysis of a part of VP1 (~300 nt was carried out. Isolates from different geographic regions were compared to each other as well as to elder viruses (prototype strain from 1953, four isolates from 1965–1986. Results Overall, 55 isolates of echovirus type 13 were obtained from different parts of Germany. It was shown that the new isolated strains have a very high degree of homology on the nucleotide level (> 98% but differ significantly from the old strains (76–85%. Conclusions a Rare enterovirus serotypes can cause serious illness. b The molecular drift has also been shown for other enterovirus serotypes.

Statement about the situation of radiation research in Germany

International Nuclear Information System (INIS)

2002-01-01

The Radiation Protection Association observes with profound concern the decline in radiation research in the Federal Republic of Germany. Among other consequences, this gives rise to the fear that Germany's influence on developments, decisions, and standards in international bodies is going to decline for lack of competence. Moreover, Germany will hardly be able to deal with the growing number of topical problems arising in radiation effects in cell biology and molecular biology. These aspects, and others, however, are going to be of overriding importance also in the future as by far most of the radiation exposure of persons is due to medical applications and is going to continue at least at the same level. It would therefore be desirable if the competent government agencies made available the necessary funds. A national coordinating agency yet to be established, which would be made up of representatives of the university and non-university institutions concerned, could define research goals and award research contracts within the framework of a research program. (orig.) [de

Food-related life style in Germany

DEFF Research Database (Denmark)

Grunert, Klaus G.; Brunsø, Karen; Bisp, Søren

1995-01-01

Executive summary 1. This report is about an investigation of food-related lifestyle in Germany, based on a representative sample of 1000 households. 2. The German consumers are described by five segments, which differ in how and to which extent they use food and cooking to attain their central l...

Novel lyssavirus in Natterer's bat, Germany.

Science.gov (United States)

Freuling, Conrad M; Beer, Martin; Conraths, Franz J; Finke, Stefan; Hoffmann, Bernd; Keller, Barbara; Kliemt, Jeannette; Mettenleiter, Thomas C; Mühlbach, Elke; Teifke, Jens P; Wohlsein, Peter; Müller, Thomas

2011-08-01

A virus isolated from a Natterer's bat (Myotis nattererii) in Germany was differentiated from other lyssaviruses on the basis of the reaction pattern of a panel of monoclonal antibodies. Phylogenetic analysis supported the assumption that the isolated virus, Bokeloh bat lyssavirus, may represent a new member of the genus Lyssavirus.

A SURVEY OF AUTOMATION TECHNIQUES COMING FORTH IN SHEET-FED OFFSET PRINTING ORGANIZATIONS

OpenAIRE

Mr. Ramesh Kumar*, Mr. Bijender & Mr. Sandeep Boora

2017-01-01

Sheet-Fed offset is one of the premier processes in India as well as abroad. To cope up with customers large quantity demands automation has become mandatory. From prepress to post press a wide range of automation techniques exist and coming forth for sheet fed offset presses. Objective of this paper is to throw light on various sheet-fed offset automation techniques existing today and their futuristic implications. The data related to automation was collected with the help of survey conducte...

Yearbook on energy from Central Germany 2012; Jahrbuch Energie aus Mitteldeutschland 2012. Die Energiewende beginnt im Kopf

Energy Technology Data Exchange (ETDEWEB)

Krueger, Simone; Kresse, Olaf (eds.)

2012-07-01

The authors of the book under consideration promote the regional cooperation and networking in Saxony, Saxony-Anhalt and Thuringia by means of the following contributions: (1) Energy policy turnaround in Central Germany - Where do we go?; (2) Energy policy turnaround in Central Germany - Opportunities for local communities; (3) Energy policy turnaround in Central Germany - Opportunities for companies in the area of energy efficiency; (4) Energy policy turnaround in Central Germany - A challenge for education and science; (5) Energy policy turnaround in Central Germany - A challenge for the human resource development of companies.

Performance and Carcass characteristics of broad breasted bronze toms fed radappertized Diet

International Nuclear Information System (INIS)

Farag, El-Din.M.H.; Mohamed, F.A.

1999-01-01

The effect of irradiated complete diets at dose level of 25 KGy was studied in broad breasted bronze tome evaluating their growing performances as well as characteristics of the carcasses. Two experimental groups received irradiated and non irradiated diets for 18 weeks (from the 5 t h to the 23 r d week of age). Four toms per treatment at the age of 23 weeks were slaughtered and the carcass was dissected. Radappertized diets improved body weight gain, feed consumption and feed conversion and reduced mortality rate. No significant differences were observed between toms fed processed and non processed diets on carcasses components, while the gizzard weight was greater for those fed the processed diets. Dressing and drawn weights in toms fed processed diets were 3% higher than in those fed non processed diets. The results suggest that sterilization of turkeys feed may have a beneficial effect on the body weight and deed conversion of turkeys consuming these diets without harmful effect on the bird

“La República de los Sueños”: De lo racional de la República a lo irracional de los sueños

Directory of Open Access Journals (Sweden)

Broullón Acuña, Esmeralda

2010-02-01

Full Text Available The Republic of the dreams is an “Atlantic novel” and as such it develops a narrative on the trip and the memory of a family of Spanish origin in the contemporary Brazil. The work investigates the process of immigration and adjustment of a Galician patriarchal and capitalist, predestined to the social success. A consecration that will go up to his last consequences, coming back to his village, of which went out in 1913, to marry the daughter of a nobleman. Founder of a lineage hispanic-brazilian will remain caught in the profit that he itself interweaves on having taken part of the networks and the oligarchic practices that dominate in the country. Thus the authoress re-composes a statement ethnic-historical where she represents the ethnic segmentation of the condition state-nation and institutes the memory and the culture as elements of resistance.

La República de los sueños es una “novela atlántica” y como tal desarrolla una narrativa sobre el viaje y la memoria de una familia de origen español en el Brasil contemporáneo. La obra indaga el proceso de inmigración y adaptación de un gallego patriarcal y capitalista, predestinado al éxito social. Una consagración que llevará hasta sus últimas consecuencias, retornando a su aldea, de la cual salió en 1913, para casarse con la hija de un hidalgo. Fundador de un linaje hispanobrasileño quedará atrapado en el lucro que él mismo entreteje al participar de las redes y las prácticas oligárquicas que dominan en el país. De este modo la autora recompone un relato etnohistórico donde representa la segmentación étnica del estado-nación e instituye la memoria y la cultura como elementos de resistencia.

Small scale wood combustion in Germany. Recent research and trends

Energy Technology Data Exchange (ETDEWEB)

Maier, H.; Unterberger, S.; Hein, K.R.G. [Institute of Process Engineering and Power Plant Technology, University of Stuttgart (Germany)

1998-12-31

To reduce Europe`s greenhouse gas emission CO{sub 2} it is a challenging task utilising biomass fuels as there are wood or wood residues from the forest industry. The utilisation can be done either in commercially operated medium (> 50 kWth) or full scale (> 1 MWth) decentralised heat and power stations or in small scale (< 50 kWth) domestic heating systems. In small scale heating systems untreated wood logs, wood briquette or wood pellets and in few cases wood chips are used. The present market in Germany is focused on the use of wood logs. Presently, the use of wood pellets in small scale automatically operated boilers < 15 kW especially for low energy houses is discussed more and more. Since 1980 the installation of new wood fired small scale domestic heating systems reached a significant size due to the interest of the customers to have a alternative inhouse heating system and to increase the living comfort. In 1994 the amount of sold small scale heaters in Germany were in total about 133.258 units. The thermal power of in 1994 sold units is estimated of about 1350 MW which is a significant size in total with regard to domestic heating purposes. Since few years there is a clear market trend in Germany towards the installation of open fire stoves. Due to this trend in Germany and the design characteristic of open fire stoves using huge glass doors of glass windows it is very difficult to achieve a further reduction of emissions like CO and unburned volatile hydrocarbons (VOC). In the text the requirements for modern small scale wood fired stoves in Germany as well as the actual stage and trend of research and development (R and D) are discussed 4 refs.

Who has really paid for the Reconstruction of East Germany? Expected and Realized Returns on Real Estate Investments in East and West Germany in the 1990s

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Dirk Kiesewetter

2009-05-01

Full Text Available We evaluate the profitability of investments in residential property in Germany after unification with a focus on the comparison of East and West Germany. Calculations are carried out for (1 the after-tax return an investor might have expected at the beginning of the 1990s, and (2 the after-tax return that has been realized ten years after. We compare a set of statistical data for investments in fifty major cities by using complete financial budgeting. The results show that tax subsidies could not always protect investors from losing money, but they have boosted realized returns after tax considerably. Therefore, it was indeed the taxpayers, not the investors, who have borne the cost of reconstructing East Germany.

[Important vector-borne infectious diseases among humans in Germany. Epidemiological aspects].

Science.gov (United States)

Frank, C; Faber, M; Hellenbrand, W; Wilking, H; Stark, K

2014-05-01

Vector-borne infections pathogenic to humans play an important role in Germany. The relevant zoonotic pathogens are either endemic throughout Germany (e.g. Borrelia burgdorferi sensu latu) or only in specific regions, e.g. tick-borne encephalitis (TBE) virus and hantavirus. They cause a substantial burden of disease. Prevention and control largely rely on public advice and the application of personal protective measures (e.g. TBE virus vaccination and protection against vectors). High quality surveillance and targeted epidemiological studies are fundamental for the evaluation of temporal and spatial risks of infection and the effectiveness of preventive measures. Aside from endemic pathogens, vector-borne infections acquired abroad, mostly transmitted by mosquitoes, have to be systematically and intensively monitored as well, to assess the risk of infection for German residents traveling abroad and to adequately evaluate the risk of autochthonous transmission. Related issues, such as invasive species of mosquitoes in Germany and climate change, have to be taken into consideration. Such pathogens include West Nile, dengue and chikungunya viruses, as well as malaria parasites (Plasmodium species). The article presents an overview of the epidemiological situation of selected relevant vector-borne infections in Germany.