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Sample records for fci related activities

  1. Review and Perspective of FCI Related Activities in Japan

    International Nuclear Information System (INIS)

    Kawaguchi, O.

    1976-01-01

    Because of its meager natural resources and high population, Japan needs a strong nuclear program. However, the high population density and the public concern about environmental pollution and safety tend to impose stringent safety criteria for nuclear plants. Safety of the LMFBR, the most promising among several nuclear options, must be established for future commercialization. One of the most crucial issues in LMFBR safety is the molten fuel coolant interaction (FCI), which comes into play in various phases of the hypothetical core disruptive accident (HCDA). The objectives of the present paper are: firstly to summarize the current FCI considerations applied in the design of the Japanese prototype FBR, MONJU; and secondly to review the supporting R and D activities. In conclusion: Although analytical model predictions for FCI work energy per plant electrical output has decreased considerably over the last few years, the current classical approach would yield an inexorable containment design for larger FBRs. The FCI issue should be resolved within the coming few years. Concentrated efforts should be directed toward: (1) Proof both with simulant materials and fuel-sodium systems of the existence of the threshold for vapor explosions. (2) Establishment with out-of-pile fuel-sodium systems of the fragmentation mechanism to evaluate the heat transfer coefficients. (3) A few carefully planned in-pile tests. (4) Development of computer codes at various levels of accident to realistically assess the initial condition, progression and consequence of an FCI event under reactor conditions. (5) Establishment of the world-wide consensus of the HCDA scenario for licensable, economical commercial FBRs. We believe that an extensive data and personnel exchange are readily available in the areas (1) and (2) above, and that the NEA/CSNI Committee should coordinate future experiments on a complementing basis. We believe that promotion of further international cooperation in the

  2. Patterns of Incorrect Responses on the FCI and Course Success

    Science.gov (United States)

    Wells, James; Mokaya, Fridah; Valente, Diego

    The Force Concept Inventory (FCI) is often used to measure the effectiveness of instructional pedagogy in introductory physics courses both at the algebra- and calculus-based level. Scores on the FCI are correlated with the performance of students in a class, as measured by their final course grade. We have collected data from several semesters of first-semester introductory mechanics courses at a public 4-year university, taught in large-scale classrooms with pedagogy including elements of Just-in-Time Teaching pedagogy along with active learning course components. The data collected includes pre- and post-test FCI scores, midterm exam grades, and final course grades. We examine whether certain patterns of incorrect answers on the FCI post-test are predictive of course grades, indicating whether certain specific student preconceptions are more detrimental than others to the success of students in an introductory mechanics course. Funding from UConn - College of Liberal Arts and Sciences (CLAS).

  3. Using a psychometric lens to examine gender differences on the FCI

    Science.gov (United States)

    Lindell, Rebecca; Papak, Alexis; Stewart, John; Traxler, Adrienne

    2017-01-01

    Multiple research studies show that there appears to be an inherent difference between male and female students' performance on the Force Concept Inventory (FCI). Unlike these studies, we chose to create two different samples, one with only female students and the other with only male students, to reduce the effects of the gender-imbalance inherent in a single sample of all physics students. Using a psychometric lens, we evaluate the differences between the male and female students' performance on the FCI. We utilized classical test theory to flag 13 items on the FCI that were poorly functioning for female students. Notably, most of these items were not flagged when the dataset was aggregated across genders. In the next stage of the research, we utilized Item Response Theory (IRT) to discover if the remaining 17 items on the FCI are also poorly functioning for female students. By eliminating the poorly functioning items on the FCI, we further examined the gender difference of the Force Concept Inventory.

  4. Expanding the FCI to Eevaluate Conceptual Mastery of Energy, Momentum, and Rotational Dynamics

    Science.gov (United States)

    Chediak, Alex; Hay, Katrina

    2010-03-01

    Normalized gain on the Force Concept Inventory (FCI) has deservedly become a widely accepted assessment tool to evaluate conceptual mastery in a high school, college, or university-level mechanics course. Left out of this assessment, however, are important physics concepts typically presented in the same course. Conservation of energy and momentum as well as rotational motion receive scant (if any) coverage on the FCI (or, for that matter, the Mechanics Baseline Test). Yet these concepts are foundational for popular majors such as mechanical engineering, where high failure rates are often a concern. A revised assessment tool is presented, one that incorporates the strengths of the FCI (and preserves the straightforward multiple choice format), but assesses these other mechanics-related concepts. Ten additional questions are included, inspired in part by material from the Physics Education Group at the University of Washington and in part by the authors' own experiences with common student misperceptions. The questions are given as pre- and post tests at the authors' institutions, California Baptist University and Pacific Lutheran University, in both calculus-based and algebra-based mechanics courses, exploring breadth of applicability for our findings. We present normalized gain data for the traditional thirty FCI questions and for our ten additional questions.

  5. Fuel-coolant interaction (FCI) phenomena in reactor safety. Current understanding and future research needs

    Energy Technology Data Exchange (ETDEWEB)

    Speis, T.P. [Maryland Univ., College Park, MD (United States); Basu, S.

    1998-01-01

    This paper gives an account of the current understanding of fuel-coolant interaction (FCI) phenomena in the context of reactor safety. With increased emphasis on accident management and with emerging in-vessel core melt retention strategies for advanced light water reactor (ALWR) designs, recent interest in FCI has broadened to include an evaluation of potential threats to the integrity of reactor vessel lower head and ex-vessel structural support, as well as the role of FCI in debris quenching and coolability. The current understanding of FCI with regard to these issues is discussed, and future research needs to address the issues from a risk perspective are identified. (author)

  6. Numerical investigation of the LM MHD flows in a curved duct with an FCI with varying slot locations

    International Nuclear Information System (INIS)

    Yang, Jong Hoon; Yan, Yue; Kim, Chang Nyung

    2016-01-01

    Highlights: • This study numerically investigates the liquid-metal magnetohydrodynamic flows in a curved duct with an FCI. • The effects of the location of FCI slot and of the curvature radius on the flow behavior are reviewed. • The influence of the FCI slot position on the equalization of the pressure in the inner fluid region (inside the FCI) and the gap fluid region (outer the FCI) is examined. - Abstract: This study numerically investigates the liquid-metal (LM) magnetohydrodynamic (MHD) flows in a curved duct with an FCI having three different slot locations and having no slot under a uniform magnetic field perpendicular to the duct. The flow velocity, current density, electric potential, Lorentz force, and pressure in different flow situations are presented in detail. The effects of the location of FCI slot and of the curvature radius on the flow behavior are reviewed. The flow field is examined with an introduction of the electric-field component and electro-motive component of the current, allowing us to analyze the interdependency of the flow variables. The effect of the FCI slot position on the equalization of the pressure in the inner fluid region (inside the FCI) and the gap fluid region (outer the FCI) is examined. The result shows that and the case with an FCI slot located in the neutral position yields the smallest pressure gradient in the main flow direction among the cases with an FCI slot, resulting in the smallest pressure drop. Also, in a flow situation with smaller radius of curvature with the FCI slot in the neutral position, the axial velocity near the inner (in terms of the curvature) part of a cross-section is higher than that near the outer part.

  7. Material analyses of foam-based SiC FCI after dynamic testing in PbLi in MaPLE loop at UCLA

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, Maria, E-mail: maria.gonzalez@ciemat.es [LNF-CIEMAT, Avda Complutense, 40, 28040 Madrid (Spain); Rapisarda, David; Ibarra, Angel [LNF-CIEMAT, Avda Complutense, 40, 28040 Madrid (Spain); Courtessole, Cyril; Smolentsev, Sergey; Abdou, Mohamed [Fusion Science and Technology Center, UCLA (United States)

    2016-11-01

    Highlights: • Samples from foam-based SiC FCI were analyzed by looking at their SEM microstructure and elemental composition. • After finishing dynamic experiments in the flowing hot PbLi, the liquid metal ingress has been confirmed due to infiltration through local defects in the protective inner CVD layer. • No direct evidences of corrosion/erosion were observed; these defects could be related to the manufacturing process. - Abstract: Foam-based SiC flow channel inserts (FCIs) developed and manufactured by Ultramet, USA are currently under testing in the flowing hot lead-lithium (PbLi) alloy in the MaPLE loop at UCLA to address chemical/physical compatibility and to access the MHD pressure drop reduction. UCLA has finished the first experimental series, where a single uninterrupted long-term (∼6500 h) test was performed on a 30-cm FCI segment in a magnetic field up to 1.8 T at the temperature of 300 °C and maximum flow velocities of ∼ 15 cm/s. After finishing the experiments, the FCI sample was extracted from the host stainless steel duct and cut into slices. Few of them have been analyzed at CIEMAT as a part of the joint collaborative effort on the development of the DCLL blanket concept in the EU and the US. The initial inspection of the slices using optical microscopic analysis at UCLA showed significant PbLi ingress into the bulk FCI material that resulted in degradation of insulating properties of the FCI. Current material analyses at CIEMAT are based on advanced techniques, including characterization of FCI samples by FESEM to study PbLi ingress, imaging of cross sections, composition analysis by EDX and crack inspection. These analyses suggest that the ingress was caused by local defects in the protective inner CVD layer that might be originally present in the FCI or occurred during testing.

  8. Design of FCI Experiments to Understand Fuel Out-Pin Phenomena in the SFR

    Energy Technology Data Exchange (ETDEWEB)

    Heo, Hyo; Park, Seong Dae [Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of); Jerng, Dong Wook; Bang, In Cheol [Chungang Univ., Seoul (Korea, Republic of)

    2014-05-15

    It is important to guarantee a passive nuclear safety regarding enhanced negative reactivity by fragmenting the molten fuel. In the SFR, it has a strong point that the negative reactivity is immediately introduced when the metal fuel is melted by the UTOP or ULOP accident. These characteristics of the metal fuel can prevent from progressing in severe accidents such as core disruptive accidents (CDA). As key phenomena in the accidents, fuel-coolant interaction (FCI) phenomena have been studied over the last few decades. Especially, several previous researches focused on instability and fragmentation of a core melt jet in water. However, the studies showed too limited phenomena to fully understand. In the domestic SFR technology development, researches for severe accidents tend to lag behind ones of other countries. Or, South Korea has a very basic level of the research such as literature survey. Recently, the SAS4A code, which was developed at Argonne National Laboratory (ANL) for thermal-hydraulic and neutronic analyses of power and flow transients in liquid-metal-cooled nuclear reactors (LMRs), is still under development to consider for a metal fuel. The other countries carried out basic experiments for molten fuel and coolant interactions. However, in a high temperature condition, methods for analysis of structural interaction between molten fuel and fuel cladding are very limited. The ultimate objective of the study is to evaluate the possibility of recriticality accident induced by fuel-coolant interaction in the SFR adopting metal fuel. It is a key point to analyze the molten-fuel behavior based on the experimental results which show fuel-coolant interaction with the simulant materials. It is necessary to establish the test facility, to build database, and to develop physical models to understand the FCI phenomena in the SFR; molten fuel-coolant interaction as soon as the molten fuel is ejected to the sodium coolant channel and molten fuel-coolant interaction

  9. Analyses of hypothetical FCI's in a fast reactor

    International Nuclear Information System (INIS)

    Padilla, A. Jr.; Martin, F.J.; Niccoli, L.G.

    1981-01-01

    Parametric analyses using the SIMMER code were performed to evaluate the potential for a severe recriticality from a pressure-driven recompaction caused by an energetic FCI during the transition phase of a hypothetical accident in a fast reactor. For realistic and reasonable estimates for the assumed accident conditions, a severe recriticality was not predicted. The conditions under which a severe recriticality would be obtained or averted were identified. 10 figures, 2 tables

  10. Implementation of FCI heating system to the control system of Tore-Supra

    International Nuclear Information System (INIS)

    Wisniewski, S.

    2001-11-01

    This report presents the implementation of the ion cyclotron resonance heating system (FCI) to the instrumentation and control system of the Tore-Supra tokamak. The new plasma heating system involves 3 antennas delivering 12 MW that are required to maintain fusion reactions. This paper is divided into 8 chapters: 1) thermonuclear fusion and Tore-Supra tokamak; 2) hardware system around Tore-Supra, in this chapter the control system and the data acquisition and processing systems are presented; 3) functional analysis, this analysis defines the different needs concerning timing and pilot-controlling, a preliminary proposition of hardware equipment is made; 4) operating modes of FCI; 5) communication within the control system network; 6) communication with the supervisory system of the power stations; 7) management of data exchange with SMX generators; and 8) control of the rate of stationary waves during the injection of power into the plasma

  11. Implementation of FCI heating system to the control system of Tore-Supra; Integration du systeme de chauffage FCI au sein du reseau de controle commande du Tokamak Tore Supra

    Energy Technology Data Exchange (ETDEWEB)

    Wisniewski, S

    2001-11-01

    This report presents the implementation of the ion cyclotron resonance heating system (FCI) to the instrumentation and control system of the Tore-Supra tokamak. The new plasma heating system involves 3 antennas delivering 12 MW that are required to maintain fusion reactions. This paper is divided into 8 chapters: 1) thermonuclear fusion and Tore-Supra tokamak; 2) hardware system around Tore-Supra, in this chapter the control system and the data acquisition and processing systems are presented; 3) functional analysis, this analysis defines the different needs concerning timing and pilot-controlling, a preliminary proposition of hardware equipment is made; 4) operating modes of FCI; 5) communication within the control system network; 6) communication with the supervisory system of the power stations; 7) management of data exchange with SMX generators; and 8) control of the rate of stationary waves during the injection of power into the plasma.

  12. Investigation of film boiling thermal hydraulics under FCI conditions. Results of a numerical study

    Energy Technology Data Exchange (ETDEWEB)

    Dinh, T.N.; Dinh, A.T.; Nourgaliev, R.R.; Sehgal, B.R. [Div. of Nuclear Power Safety Royal Inst. of Tech. (RIT), Brinellvaegen 60, 10044 Stockholm (Sweden)

    1998-01-01

    Film boiling on the surface of a high-temperature melt jet or of a melt particle is one of key phenomena governing the physics of fuel-coolant interactions (FCIs) which may occur during the course of a severe accident in a light water reactor (LWR). A number of experimental and analytical studies have been performed, in the past, to address film boiling heat transfer and the accompanying hydrodynamic aspects. Most of the experiments have, however, been performed for temperature and heat flux conditions, which are significantly lower than the prototypic conditions. For ex-vessel FCIs, high liquid subcooling can significantly affect the FCI thermal hydraulics. Presently, there are large uncertainties in predicting natural-convection film boiling of subcooled liquids on high-temperature surfaces. In this paper, research conducted at the Division of Nuclear Power Safety, Royal Institute of Technology (RIT/NPS), Stockholm, concerning film-boiling thermal hydraulics under FCI condition is presented. Notably, the focus is placed on the effects of (1) water subcooling, (2) high-temperature steam properties, (3) the radiation heat transfer and (4) mixing zone boiling dynamics, on the vapor film characteristics. Numerical investigations are performed using a novel CFD modeling concept named as the local-homogeneous-slip model (LHSM). Results of the analytical and numerical studies are discussed with respect to boiling dynamics under FCI conditions. (author)

  13. Recent status of FCI: PIC simulation of coupled-cavity structure

    International Nuclear Information System (INIS)

    Shintake, Tsumoru

    1996-01-01

    New version of FCI (Field Charge Interaction)-code simulates beam dynamics of an electron beam running in a coupled-cavity structure, such as a multi-cell output structure in a klystron amplifier, a coupled cavity TWT amplifier, a bunching structure in an electron injector and also an rf-gun with multi-cell accelerating cavity. The particle-in-cell simulation takes into account the space charge field, the beam loading effect and energy exchange with an external circuit in a self-consistent manner. (author)

  14. Examining gender differences on FCI performance in algebra and calculus based physics courses

    Science.gov (United States)

    Kreutzer, Kimberley; Boudreaux, Andrew

    2009-05-01

    The Force Concept Inventory (FCI) has been widely used to asses student understanding of Newtonian principles. Studies have shown a marked difference in the performance of men and women on both pre- and post-tests [1,2] and also indicate that experiential based instruction may lead to a reduction in this gender gap [1,3]. This poster presents FCI data collected at Western Washington University. Initial analysis of gender differences are consistent with those reported nationally. We also discuss factors that may contribute to the differences in performance and propose instructional strategies that are designed to address the gender gap. [4pt] [1] M. Lorenzo, et. al., ``Reducing the gender gap in the physics classroom,'' AJP 74(2), 118-122 (2006) [0pt] [2] J. Docktor and K. Heller, ``Gender Differences in Both Force Concept Inventory and Introductory Physics Performance,'' Proceedings at the 2008 PERC [0pt] [3] S. Pollack, et. al., ``Reducing the gender gap in the physics classroom: How sufficient is interactive engagement?'' PRST-PER 3 (2007)

  15. 78 FR 49469 - Stephen Glen Guerra, Inmate #98595-279, FCI Yazoo City Medium, Federal Correctional Institution...

    Science.gov (United States)

    2013-08-14

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Stephen Glen Guerra, Inmate 98595-279, FCI... Export Privileges On February 6, 2012, in the U.S. District Court, Western District of Texas, Stephen... conviction. [[Page 49470

  16. FCI: remedy development for the fuel performance improvement program

    International Nuclear Information System (INIS)

    Buckman, F.W.; Crouthamel, C.E.; Freshley, M.D.

    1979-01-01

    Out-of-reactor experiments and irradiations are being utilized to develop and demonstrate the efficacy of specific advanced fuel designs to improve FCI behavior. The advanced light water reactor fuel designs being evaluated combine annular pellets, graphite coating on the inner surface of the cladding, and helium pressurization. A sphere-pac fuel design is also being developed. Characterization of the graphite coatings includes studies of composition, application methods, thickness control, moisture control, thermal conductivity, compatibility with the zircaloy cladding, strain-to-failure, and friction and wear characteristics. Rods of the different fuel designs, as well as reference rods, are being irradiated in the Halden Boiling Water Reactor and the Big Rock Point Reactor to accumulate burnup prior to ramping tests

  17. 78 FR 76813 - Igor Bobel, Inmate #-67253-066, FCI Loretto, Federal Correctional Institution, P.O. Box 1000...

    Science.gov (United States)

    2013-12-19

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Igor Bobel, Inmate -67253-066, FCI Loretto, Federal Correctional Institution, P.O. Box 1000, Loretto, PA 15940; Order Denying Export Privileges On May... 1000, Loretto, PA 15940, and when acting for or on behalf of Bobel, his representatives, assigns...

  18. 78 FR 49470 - Adrian Jesus Reyna, Inmate Number #80629-280, FCI Bastrop, Federal Correctional Institution, P.O...

    Science.gov (United States)

    2013-08-14

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Adrian Jesus Reyna, Inmate Number 80629-280... Privileges On January 27, 2012, in the U.S. District Court, Western District of Texas, Adrian Jesus Reyna.... Until January 27, 2022, Adrian Jesus Reyna, with a last known address at: Inmate Number 80629-280, FCI...

  19. FCI experiments and analysis. Contributions to basic understanding

    International Nuclear Information System (INIS)

    Corradini, M.L.; Cho, D.; Magallon, D.; Basu, S.

    1998-01-01

    Past safety analyses considered the hazard from vapor explosions in a conservative manner where engineering judgement and conservative analyses were used to estimate the likelihood of nuclear reactor containment failure from explosion-induced missile generation (alpha-mode failure). However, recent safety analyses may require less conservative methods to determine the hazard from vapor explosions; thus, one may need to consider more detailed scaling of vapor explosion energetics, considering fuel-coolant mixing and explosion propagation. The United States Nuclear Regulatory Commission is supporting a coordinated set of experiments to address this issue, given a lack of appropriate benchmark data and associated analyses. These experiments, KROTOS, WFCI and ZrEX are mutually complimentary and provide the first consistent set of data for FCI phenomena under controlled conditions for a wide range of simulant materials that approximate the fuel melt. The scaling logic for these tests is that essentially one-dimensional geometry with rigid constraints would maximize the explosion energetics for a given set of mixing conditions. Thus, only variations in the axial boundary conditions and fuel-coolant initial conditions (mass, composition and temperatures) can affect the mixing and energetics. Our hypothesis is that clear limits to energetics below thermodynamic values can be identified for these high temperature fuel melts along with fundamental understanding, which can aid in issue resolution. (author)

  20. KROTOS FCI experimental programme at CEA Cadarache: new features and status

    International Nuclear Information System (INIS)

    Bonnet, J.M.; Bullado, Y.; Journeau, C.; Fouquart, P.; Piluso, P.; Sergeant, C.; Magallon, D.

    2005-01-01

    Full text of publication follows: KROTOS facility has been operated by the European Commission at JRC-Ispra for many years until 1999 as part of the FARO/KROTOS programme. The programme had to be stopped at JRC due to new EC priorities, and an agreement was concluded with CEA to transfer the KROTOS facility and know-how to Cadarache to continue investigating the pending FCI issues. By this agreement, CEA became owner of the facility. The main objective of the KROTOS programme at CEA Cadarache is understanding the role of melt properties in steam explosion propagation and energetics and, in particular, steam explosion behaviour of prototypical corium melts. Possible influence of physicochemical processes on explosiveness will also be explored. Actually, analysis of alumina debris produced at Ispra have shown that formation of metastable phases and chemical reaction with water at high temperature may play a significant role in enhancing heat transfer to water in the explosion phase. In order to reach the objective, steam explosion experiments are performed in well characterised conditions for a large spectrum of conditions and melt compositions of interest for both in- and ex-vessel situations. A trigger is applied as a rule. Advanced technology and instrumentation is used to reduce uncertainties on initial conditions and characterise the various phases of an explosion, with emphasis on high energy X-ray cinematography to qualify pre-mixing. This advanced instrumentation will enable the measurement of detailed variables to consolidate the qualification of the FCI codes. The use of high energy X-rays made it necessary to construct a new building to house the facility and its components. The facility should newly become operative early 2005. Main improvements with respect to Ispra concern melt delivery, hydrogen measurement and X-ray imaging. Preliminary studies have demonstrated that identification of the pre-mixture-water interface and coherent melt jet core, and

  1. KROTOS FCI experimental programme at CEA Cadarache: new features and status

    Energy Technology Data Exchange (ETDEWEB)

    Bonnet, J.M.; Bullado, Y.; Journeau, C.; Fouquart, P.; Piluso, P.; Sergeant, C.; Magallon, D. [CEA-Cadarache, DTN/STRI/LMA, Bat 708, BP1, 13108 Saint Paul lez Durance cedex (France)

    2005-07-01

    Full text of publication follows: KROTOS facility has been operated by the European Commission at JRC-Ispra for many years until 1999 as part of the FARO/KROTOS programme. The programme had to be stopped at JRC due to new EC priorities, and an agreement was concluded with CEA to transfer the KROTOS facility and know-how to Cadarache to continue investigating the pending FCI issues. By this agreement, CEA became owner of the facility. The main objective of the KROTOS programme at CEA Cadarache is understanding the role of melt properties in steam explosion propagation and energetics and, in particular, steam explosion behaviour of prototypical corium melts. Possible influence of physicochemical processes on explosiveness will also be explored. Actually, analysis of alumina debris produced at Ispra have shown that formation of metastable phases and chemical reaction with water at high temperature may play a significant role in enhancing heat transfer to water in the explosion phase. In order to reach the objective, steam explosion experiments are performed in well characterised conditions for a large spectrum of conditions and melt compositions of interest for both in- and ex-vessel situations. A trigger is applied as a rule. Advanced technology and instrumentation is used to reduce uncertainties on initial conditions and characterise the various phases of an explosion, with emphasis on high energy X-ray cinematography to qualify pre-mixing. This advanced instrumentation will enable the measurement of detailed variables to consolidate the qualification of the FCI codes. The use of high energy X-rays made it necessary to construct a new building to house the facility and its components. The facility should newly become operative early 2005. Main improvements with respect to Ispra concern melt delivery, hydrogen measurement and X-ray imaging. Preliminary studies have demonstrated that identification of the pre-mixture-water interface and coherent melt jet core, and

  2. FCI experiments in the corium/water system

    Energy Technology Data Exchange (ETDEWEB)

    Huhtiniemi, I.; Hohmann, H.; Magallon, D.

    1995-09-01

    The KROTOS fuel coolant interaction (FCI) tests aim at providing benchmark data to examine the effect of fuel/coolant initial conditions and mixing on explosion energetics. Experiments, fundamental in nature, are performed in well-controlled geometries and are complementary to the FARO large scale tests. Recently, a new test series was started using 3 kg of prototypical core material (80 w/o UO{sub 2}, 20 w/o ZrO{sub 2}) which was poured into a water column of {le} 1.25 m in height (95 mm and 200 mm in diameter) under 0.1 MPa ambient pressure. Four tests have been performed in the test section of 95 mm in diameter (ID) with different subcooling levels (10-80K) and with and without an external trigger. Additionally, one test has been performed with a test section of 200 mm in diameter (ID) and with an external trigger. No spontaneous or triggered energetic FCIs (steam explosions) have been observed in these corium tests. This is in sharp contrast with the steam explosions observed in the previously reported Al{sub 2}O{sub 3} test series which had the same initial conditions of ambient pressure and subcooling. The post-test analysis of the corium experiments indicated that strong vaporisation at the melt/water contact led to a partial expulsion of the melt from the test section into the pressure vessel. In order to avoid this and to obtain a good penetration and premixing os the corium melt, an additional test has been performed with a larger diameter test section. In all the UO{sub 2}-ZrO{sub 2} tests an efficient quenching process (0.7-1.2 MW/kg-melt) with total fuel fragmentation (mass mean diameter 1.4-2.5 mm) was observed. Results from Al{sub 2}O{sub 3} tests under the same initial conditions are also presented for further confirmation of the observed differences in behaviour between Al{sub 2}O{sub 3} and UO{sub 2}-ZrO{sub 2} melts.

  3. Experimental Study on Conversion of Stored Thermal Energy to Mechanical Work in FCI

    International Nuclear Information System (INIS)

    Fujii-e, Y.; Kondo, S.; Mivazaki, K.

    1976-01-01

    In the present study the process how the thermal energy stored in the coolant should be converted into the mechanical work is emphasized as well as the generation of pressure waves, eliminating the complicated problems involved in FCI, such as fragmentation, heat transfer from molten fuel to coolant, etc. A simulation experiment has been performed in a small scale vertical channel using stagnant potassium. Large superheat inherent in liquid metals was utilized as the method to accumulate the thermal energy. The following experimental parameters were chosen to examine their effects on the energy conversion ratio: the heat flux, the cover gas pressure, the liquid column length, the temperature of the upper unheated region and the incipient boiling superheat (corresponding to the stored thermal energy). The results are summarized that the conversion ratio from thermal to kinetic energies has increasing trends with increases of the incipient boiling superheat, the cover gas pressure and the temperature of upper unheated region, ranging over 0.02-0.75% in the present experiment. The important conclusions of the present experiment are summarized as follows. The thermal to kinetic energy conversion ratio n k ranges over 0.02-0.75 % for ΔT s = 10-150 deg.C, estimating from the maximum velocity measured. The thermal to mechanical work conversion ratio n w ranges over 0.14-5.6%. The effect of the heat flux on the both conversion ratios is small within the range covered by the present experiment (g≤133 W/cm 2 ). The effect of the liquid column length is not presented. The thermal to kinetic energy conversion ratio increases with the incipient boiling superheat which corresponds to the stored thermal energy in the present experiment. The both conversion ratio decrease with a decrease of the cover gas pressure. This is attributable to the thermal contact in the upper unheated region. The both conversion ratios increase with an increase in the temperature of the upper

  4. Analysis of direct containment heating in Ling'ao-2 nuclear power plant model With FCI-CMFD software

    International Nuclear Information System (INIS)

    Wang Xi; Yang Yanhua; Huang Xi

    2010-01-01

    Ling'ao 2 Nuclear Power Plant (NPP) model was established in the paper. Three dimensional numerical calculation code MC3D was used for analyzing the potential direct containment heating (DCH) accident in the model. MC3D is a special software for fuel coolant interaction (FCI) analysis. In order to predict the accident accurately, initial conditions provided by the SBO accident calculation and the geometric model of Ling'ao 2 NPP were combined to simulate the process of the accident. The calculation gives temperature field, droplet Janume fraction field, velocity field, and the pressure variation in the containment in the case of accident. The result shows that DCH will cause the pressure rising rapidly in the containment and in some local areas temperature rises too. (authors)

  5. Comparative assessment of three different indices of multimorbidity for studies on health-related quality of life

    Directory of Open Access Journals (Sweden)

    Dubois Marie-France

    2005-11-01

    Full Text Available Abstract Background Measures of multimorbidity are often applied to source data, populations or outcomes outside the scope of their original developmental work. As the development of a multimorbidity measure is influenced by the population and outcome used, these influences should be taken into account when selecting a multimorbidity index. The aim of this study was to compare the strength of the association of health-related quality of life (HRQOL with three multimorbidity indices: the Cumulative Illness Rating Scale (CIRS, the Charlson index (Charlson and the Functional Comorbidity Index (FCI. The first two indices were not developed in light of HRQOL. Methods We used data on chronic diseases and on the SF-36 questionnaire assessing HRQOL of 238 adult primary care patients who participated in a previous study. We extracted all the diagnoses for every patient from chart review to score the CIRS, the FCI and the Charlson. Data for potential confounders (age, sex, self-perceived economic status and self-perceived social support were also collected. We calculated the Pearson correlation coefficients (r of the SF-36 scores with the three measures of multimorbidity, as well as the coefficient of determination, R2, while controlling for confounders. Results The r values for the CIRS (range: -0.55 to -0.18 were always higher than those for the FCI (-0.47 to -0.10 and Charlson (-0.31 to -0.04 indices. The CIRS explained the highest percent of variation in all scores of the SF-36, except for the Mental Component Summary Score where the variation was not significant. Variations explained by the FCI were significant in all scores of SF-36 measuring physical health and in two scales evaluating mental health. Variations explained by the Charlson were significant in only three scores measuring physical health. Conclusion The CIRS is a better choice as a measure of multimorbidity than the FCI and the Charlson when HRQOL is the outcome of interest. However

  6. Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice

    Directory of Open Access Journals (Sweden)

    Ulkan Kilic

    2017-08-01

    Full Text Available Apart from its potent antioxidant property, recent studies have revealed that melatonin promotes PI3K/Akt phosphorylation following focal cerebral ischemia (FCI in mice. However, it is not clear (i whether increased PI3K/Akt phosphorylation is a concomitant event or it directly contributes to melatonin's neuroprotective effect, and (ii how melatonin regulates PI3K/Akt signaling pathway after FCI. In this study, we showed that Akt was intensively phosphorylated at the Thr308 activation loop as compared with Ser473 by melatonin after FCI. Melatonin treatment reduced infarct volume, which was reversed by PI3K/Akt inhibition. However, PI3K/Akt inhibition did not inhibit melatonin's positive effect on brain swelling and IgG extravasation. Additionally, phosphorylation of mTOR, PTEN, AMPKα, PDK1 and RSK1 were increased, while phosphorylation of 4E-BP1, GSK-3α/β, S6 ribosomal protein were decreased in melatonin treated animals. In addition, melatonin decreased apoptosis through reduced p53 phosphorylation by the PI3K/Akt pathway. In conclusion, we demonstrated the activation profiles of PI3K/Akt signaling pathway components in the pathophysiological aspect of ischemic stroke and melatonin's neuroprotective activity. Our data suggest that Akt phosphorylation, preferably at the Thr308 site of the activation loop via PDK1 and PTEN, mediates melatonin's neuroprotective activity and increased Akt phosphorylation leads to reduced apoptosis. Keywords: PI3K/Akt signaling pathway, PI3K inhibition, Melatonin, Brain injury

  7. OECD/CSNI specialist meeting on fuel coolant interactions: summary and conclusions

    International Nuclear Information System (INIS)

    1997-01-01

    Research activities and interest on fuel-coolant interaction (FCI) have been increased and broadened since the last CSNI Specialist Meeting held in January 1993. Significant experimental and analytical research has been performed in many OECD countries and others. The growing international interest is, in large part, due to the emphasis on broader aspects of FCI ranging from melt quenching and coolability to energetic explosions (both in- and ex-vessel), and their relevance and applications to next-generation reactor design as well as accident management strategies. The objectives of the meeting are to review the knowledge and to obtain consensus on the phenomenology of FCI and in predicting FCI behavior in LWRs severe accidents; to identify those areas of FCI phenomena and prediction which are important for reactor safety but still poorly understood and require further study with clear methodologies; to inform the community and the regulatory agencies of the status of FCI issues, especially in the application to accident management and future reactor designs. The various sessions are: reactor applications, pre-mixing, propagation / trigger, experiments

  8. Current food chain information provides insufficient information for modern meat inspection of pigs.

    Science.gov (United States)

    Felin, Elina; Jukola, Elias; Raulo, Saara; Heinonen, Jaakko; Fredriksson-Ahomaa, Maria

    2016-05-01

    control the main biological public health hazards related to pork, serological surveillance should be done and the information obtained from analyses should be used as part of the FCI. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Age and education corrected older adult normative data for a short form version of the Financial Capacity Instrument.

    Science.gov (United States)

    Gerstenecker, Adam; Eakin, Amanda; Triebel, Kristen; Martin, Roy; Swenson-Dravis, Dana; Petersen, Ronald C; Marson, Daniel

    2016-06-01

    Financial capacity is an instrumental activity of daily living (IADL) that comprises multiple abilities and is critical to independence and autonomy in older adults. Because of its cognitive complexity, financial capacity is often the first IADL to show decline in prodromal and clinical Alzheimer's disease and related disorders. Despite its importance, few standardized assessment measures of financial capacity exist and there is little, if any, normative data available to evaluate financial skills in the elderly. The Financial Capacity Instrument-Short Form (FCI-SF) is a brief measure of financial skills designed to evaluate financial skills in older adults with cognitive impairment. In the current study, we present age- and education-adjusted normative data for FCI-SF variables in a sample of 1344 cognitively normal, community-dwelling older adults participating in the Mayo Clinic Study of Aging (MCSA) in Olmsted County, Minnesota. Individual FCI-SF raw scores were first converted to age-corrected scaled scores based on position within a cumulative frequency distribution and then grouped within 4 empirically supported and overlapping age ranges. These age-corrected scaled scores were then converted to age- and education-corrected scaled scores using the same methodology. This study has the potential to substantially enhance financial capacity evaluations of older adults through the introduction of age- and education-corrected normative data for the FCI-SF by allowing clinicians to: (a) compare an individual's performance to that of a sample of similar age and education peers, (b) interpret various aspects of financial capacity relative to a normative sample, and (c) make comparisons between these aspects. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  10. OECD/SERENA Project Report. Summary and Conclusions

    International Nuclear Information System (INIS)

    2015-02-01

    involving nominally 20 kilograms of prototypic melt. The analytical programme was aimed at complementing the analytical work in WGAMA/SERENA activity, completed in 2006, by integrating the results of the experimental programme in the current phase, and by updating the capabilities of the FCI models/codes for use in reactor safety analysis. The scope of the reactor application exercise was to verify whether progress made in the SERENA programme in understanding and modelling key FCI phenomena for reactor applications (mainly phenomena related to premixing, e.g., jet fragmentation, voiding, melt solidification, etc., as well as the role of melt properties) contributed to a reduction of scatter in code predictions for ex-vessel FCI, observed in the WGAMA/SERENA activity. A better consistency of the results was noted between various FCI codes although some discrepancies still exist on the absolute values. The scatter in most 2-D simulations is more due to the ultimate choice of the parameters (e.g., fragmentation criteria in the explosion phase) than to fundamental differences in the physics. This discrepancy will reduce further when the codes will have improved models based on the new experimental data produced in the project. Note the current experimental data have not been fully capitalised yet; accordingly, it will take some time to improve the models. The OECD/SERENA project accomplished in large part its stated objectives. The project generated new experimental data for development of new phenomenological models closed to real reactor case conditions (corium composition), improvement of existing models, and assessment of FCI codes. The project also provided new insights; however, it would be sometime before the insights can be fully integrated into new and improved models and codes. It should be noted that the FCI models and codes can only be as precise as the experimental data and that there are inherent uncertainties in experimental data. While from a regulatory and

  11. Comparing large lecture mechanics curricula using the Force Concept Inventory: A five thousand student study

    Science.gov (United States)

    Caballero, Marcos D.; Greco, Edwin F.; Murray, Eric R.; Bujak, Keith R.; Jackson Marr, M.; Catrambone, Richard; Kohlmyer, Matthew A.; Schatz, Michael F.

    2012-07-01

    The performance of over 5000 students in introductory calculus-based mechanics courses at the Georgia Institute of Technology was assessed using the Force Concept Inventory (FCI). Results from two different curricula were compared: a traditional mechanics curriculum and the Matter & Interactions (M&I) curriculum. Both were taught with similar interactive pedagogy. Post-instruction FCI averages were significantly higher for the traditional curriculum than for the M&I curriculum; the differences between curricula persist after accounting for factors such as pre-instruction FCI scores, grade point averages, and SAT scores. FCI performance on categories of items organized by concepts was also compared; traditional averages were significantly higher in each concept. We examined differences in student preparation between the curricula and found that the relative fraction of homework and lecture topics devoted to FCI force and motion concepts correlated with the observed performance differences. Concept inventories, as instruments for evaluating curricular reforms, are generally limited to the particular choice of content and goals of the instrument. Moreover, concept inventories fail to measure what are perhaps the most interesting aspects of reform: the non-overlapping content and goals that are not present in courses without reform.

  12. Deriving common comorbidity indices from the MedDRA classification and exploring their performance on key outcomes in patients with rheumatoid arthritis.

    Science.gov (United States)

    Putrik, Polina; Ramiro, Sofia; Lie, Elisabeth; Michaud, Kaleb; Kvamme, Maria K; Keszei, Andras P; Kvien, Tore K; Uhlig, Till; Boonen, Annelies

    2018-03-01

    To develop algorithms for calculating the Rheumatic Diseases Comorbidity Index (RDCI), Charlson-Deyo Index (CDI) and Functional Comorbidity Index (FCI) from the Medical Dictionary for Regulatory Activities (MedDRA), and to assess how these MedDRA-derived indices predict clinical outcomes, utility and health resource utilization (HRU). Two independent researchers linked the preferred terms of the MedDRA classification into the conditions included in the RDCI, the CDI and the FCI. Next, using data from the Norwegian Register-DMARD study (a register of patients with inflammatory joint diseases treated with DMARDs), the explanatory value of these indices was studied in models adjusted for age, gender and DAS28. Model fit statistics were compared in generalized estimating equation (prediction of outcome over time) models using as outcomes: modified HAQ, HAQ, physical and mental component summary of SF-36, SF6D and non-RA related HRU. Among 4126 patients with RA [72% female, mean (s.d.) age 56 (14) years], median (interquartile range) of RDCI at baseline was 0.0 (1.0) [range 0-6], CDI 0.0 (0.0) [0-7] and FCI 0.0 (1.0) [0-6]. All the comorbidity indices were associated with each outcome, and differences in their performance were moderate. The RDCI and FCI performed better on clinical outcomes: modified HAQ and HAQ, hospitalization, physical and mental component summary, and SF6D. Any non-RA related HRU was best predicted by RDCI followed by CDI. An algorithm is now available to compute three commonly used comorbidity indices from MedDRA classification. Indices performed comparably well in predicting a variety of outcomes, with the CDI performing slightly worse when predicting outcomes reflecting functioning and health. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  13. Fuel Coolant Interaction Results in the Fuel Pins Melting Facility (PMF)

    International Nuclear Information System (INIS)

    Urunashi, H.; Hirabayashi, T.; Mizuta, H.

    1976-01-01

    The experimental work related to FCI at PNC has been concentrated into the molten UO 2 dropping test. After the completion of molten UO 2 drop experiments, emphasis is directed toward the FCI phenomena of the initiating conditions of the accident under the more realistic geometry. The experiments are conducted within the Pin Melt Facility (PMF) in which UO 2 pellets clad in stainless steel are melted by direct electric heating under the stagnant or flowing sodium. The primary objectives of the PMF test are to: - obtain detail experimental results (heat-input, clad temperature, sodium temperature, etc.) on the FCI under TOP and LOF conditions; - observe the movement of the fuel before and after the pin failure by the X-ray cinematography; - observe the degree of coherence of the pin failures; - accumulate the experience of the FCI experiment which is applicable to the subassembly or more larger scale; - simulate the fuel behavior of the in-pile test (GETR, CABRI). The preliminary conclusions can be drawn from the foregoing observations are as follows: - Although the fuel motion and FCI of the closed test section appeared to be different from those of the open test section, the conclusion of the effect of the inside pressure on FCI needs more experimental data. - The best heating condition of the UO 2 pellet for the FCI study with PMF is established as 40 w/cm at the steady state and 1680 J/g of UO 2 during the additional transient state. The total energy deposition of the UO 2 pellet is thus estimated in the range of 2400 J/g of UO 2 -2600 J/g of UO 2 . The analytical model of the fuel pin failure and the subsequent FCI are suggested to count the following parameters: - The fuel pin failure due to the fuel vaporization due to the rapid energy deposition; - Molten fuel, clad and sodium interaction in the fuel pin after the pin failure; - The upward flow of molten fuel with molten clad or vapor sodium, as well as the slumping of molten fuel

  14. Teaching assistants’ performance at identifying common introductory student difficulties in mechanics revealed by the Force Concept Inventory

    Directory of Open Access Journals (Sweden)

    Alexandru Maries

    2016-05-01

    Full Text Available The Force Concept Inventory (FCI has been widely used to assess student understanding of introductory mechanics concepts by a variety of educators and physics education researchers. One reason for this extensive use is that many of the items on the FCI have strong distractor choices which correspond to students’ alternate conceptions in mechanics. Instruction is unlikely to be effective if instructors do not know the common alternate conceptions of introductory physics students and explicitly take into account students’ initial knowledge states in their instructional design. Here, we discuss research involving the FCI to evaluate one aspect of the pedagogical content knowledge of teaching assistants (TAs: knowledge of introductory student alternate conceptions in mechanics as revealed by the FCI. For each item on the FCI, the TAs were asked to identify the most common incorrect answer choice of introductory physics students. This exercise was followed by a class discussion with the TAs related to this task, including the importance of knowing student difficulties in teaching and learning. Then, we used FCI pretest and post-test data from a large population (∼900 of introductory physics students to assess the extent to which TAs were able to identify alternate conceptions of introductory students related to force and motion. In addition, we carried out think-aloud interviews with graduate students who had more than two semesters of teaching experience in recitations to examine how they reason about the task. We find that while the TAs, on average, performed better than random guessing at identifying introductory students’ difficulties with FCI content, they did not identify many common difficulties that introductory physics students have after traditional instruction. We discuss specific alternate conceptions, the extent to which TAs are able to identify them, and results from the think-aloud interviews that provided valuable information

  15. Relations between representational consistency, conceptual understanding of the force concept, and scientific reasoning

    Directory of Open Access Journals (Sweden)

    Pasi Nieminen

    2012-05-01

    Full Text Available Previous physics education research has raised the question of “hidden variables” behind students’ success in learning certain concepts. In the context of the force concept, it has been suggested that students’ reasoning ability is one such variable. Strong positive correlations between students’ preinstruction scores for reasoning ability (measured by Lawson’s Classroom Test of Scientific Reasoning and their learning of forces [measured by the Force Concept Inventory (FCI] have been reported in high school and university introductory courses. However, there is no published research concerning the relation between students’ ability to interpret multiple representations consistently (i.e., representational consistency and their learning of forces. To investigate this, we collected 131 high school students’ pre- and post-test data of the Representational Variant of the Force Concept Inventory (for representational consistency and the FCI. The students’ Lawson pretest data were also collected. We found that the preinstruction level of students’ representational consistency correlated strongly with student learning gain of forces. The correlation (0.51 was almost equal to the correlation between Lawson prescore and learning gain of forces (0.52. Our results support earlier findings which suggest that scientific reasoning ability is a hidden variable behind the learning of forces. In addition, we suggest that students’ representational consistency may also be such a factor, and that this should be recognized in physics teaching.

  16. Numerical modeling of first experiments on PbLi MHD flows in a rectangular duct with foam-based SiC flow channel insert

    Energy Technology Data Exchange (ETDEWEB)

    Smolentsev, S., E-mail: sergey@fusion.ucla.edu [University of California, Los Angeles (United States); Courtessole, C.; Abdou, M.; Sharafat, S. [University of California, Los Angeles (United States); Sahu, S. [Institute of Plasma Research (India); Sketchley, T. [University of California, Los Angeles (United States)

    2016-10-15

    Highlights: • Numerical studies were performed as a pre-experimental analysis to the experiment on MHD PbLi flows in a rectangular duct with a flow channel insert (FCI). • Dynamic testing of foam-based SiC foam-based CVD coated FCI has been performed using MaPLE facility at UCLA. • Two physical models were proposed to explain the experimental results and 3D and 2D computations performed using COMSOL, HIMAG and UCLA codes. • The obtained results suggest that more work on FCI development, fabrication and testing has to be done to assure good hermetic properties before the implementation in a fusion device. - Abstract: A flow channel insert (FCI) is the key element of the DCLL blanket concept. The FCI serves as electrical and thermal insulator to reduce the MHD pressure drop and to decouple the temperature-limited ferritic structure from the flowing hot lead-lithium (PbLi) alloy. The main focus of the paper is on numerical computations to simulate MHD flows in the first experiments on PbLi flows in a stainless steel rectangular duct with a foam-based silicon carbide (SiC) FCI. A single uninterrupted long-term (∼6500 h) test has recently been performed on a CVD coated FCI sample in the flowing PbLi in a magnetic field up to 1.5 T at the PbLi temperature of 300 °C using the MaPLE loop at UCLA. An unexpectedly high MHD pressure drop measured in this experiment suggests that a PbLi ingress into the FCI occurred in the course of the experiment, resulting in degradation of electroinsulating FCI properties. The ingress through the protective CVD layer was further confirmed by the post-experimental microscopic analysis of the FCI. The numerical modeling included 2D and 3D computations using HIMAG, COMSOL and a UCLA research code to address important flow features associated with the FCI finite length, fringing magnetic field, rounded FCI corners and also to predict changes in the MHD pressure drop in the unwanted event of a PbLi ingress. Two physical

  17. Analysis of information on food chain in Europe and Piedmont region, Italy

    Directory of Open Access Journals (Sweden)

    Daniele Pattono

    2014-09-01

    Full Text Available Food chain information (FCI is an innovation of the new European regulation. Its purpose is to enhance the concept of food security. FCI includes specifications such as: health status, information on treatments and diseases, analytical reports on control plans, zoonoses or environmental contaminants, production performance, etc. The aim of this article is to compare the different European guidelines and analyse the situation in Piedmont in order to assess potential problems and propose solutions. European guidelines are similar one another, but they have been tailored to the epidemiological situations of each state. Except for Spain and Germany, FCI models are different for each species and the poultry sector is the most detailed. Unfortunately, Italy has not provided guidelines yet, and this has generated considerable differences. Overall, the number of FCI models with incomplete information is the largest group compared to the models not completed for each entry. The main deficiencies are related to pharmacological treatments. The health status of the farm is listed consistently regarding the compulsory eradication plans, but other national voluntary or accreditation plans are rarely mentioned. The situation is similar in other European countries. In conclusion, FCI is an effective tool if applied with consistency and reason. Only in this way the collection of data will be effective and representative of the food chain.

  18. Applying the Socratic Method to Physics Education

    Science.gov (United States)

    Corcoran, Ed

    2005-04-01

    We have restructured University Physics I and II in accordance with methods that PER has shown to be effective, including a more interactive discussion- and activity-based curriculum based on the premise that developing understanding requires an interactive process in which students have the opportunity to talk through and think through ideas with both other students and the teacher. Studies have shown that in classes implementing this approach to teaching as compared to classes using a traditional approach, students have significantly higher gains on the Force Concept Inventory (FCI). This has been true in UPI. However, UPI FCI results seem to suggest that there is a significant conceptual hole in students' understanding of Newton's Second Law. Two labs in UPI which teach Newton's Second Law will be redesigned replacing more activity with students as a group talking through, thinking through, and answering conceptual questions asked by the TA. The results will be measured by comparing FCI results to those from previous semesters, coupled with interviews. The results will be analyzed, and we will attempt to understand why gains were or were not made.

  19. Heat transfer and thermal stress analysis in fluid-structure coupled field

    International Nuclear Information System (INIS)

    Li, Ming-Jian; Pan, Jun-Hua; Ni, Ming-Jiu; Zhang, Nian-Mei

    2015-01-01

    In this work, three-dimensional simulation on conjugate heat transfer in a fluid-structure coupled field was carried out. The structure considered is from the dual-coolant lithium-lead (DCLL) blanket, which is the key technology of International Thermo-nuclear Experimental Reactor (ITER). The model was developed based on finite element-finite volume method and was employed to investigate mechanical behaviours of Flow Channel Insert (FCI) and heat transfer in the blanket under nuclear reaction. Temperature distribution, thermal deformation and thermal stresses were calculated in this work, and the effects of thermal conductivity, convection heat transfer coefficient and flow velocity were analyzed. Results show that temperature gradients and thermal stresses of FCI decrease when FCI has better heat conductivity. Higher convection heat transfer coefficient will result in lower temperature, thermal deformations and stresses in FCI. Analysis in this work could be a theoretical basis of blanket optimization. - Highlights: • We use FVM and FEM to investigate FCI structural safety considering heat transfer and FSI effects. • Higher convective heat transfer coefficient is beneficial for the FCI structural safety without much affect to bulk flow temperature. • Smaller FCI thermal conductivity can better prevent heat leakage into helium, yet will increase FCI temperature gradient and thermal stress. • Three-dimensional simulation on conjugate heat transfer in a fluid-structure coupled field was carried out

  20. A sparse matrix based full-configuration interaction algorithm

    International Nuclear Information System (INIS)

    Rolik, Zoltan; Szabados, Agnes; Surjan, Peter R.

    2008-01-01

    We present an algorithm related to the full-configuration interaction (FCI) method that makes complete use of the sparse nature of the coefficient vector representing the many-electron wave function in a determinantal basis. Main achievements of the presented sparse FCI (SFCI) algorithm are (i) development of an iteration procedure that avoids the storage of FCI size vectors; (ii) development of an efficient algorithm to evaluate the effect of the Hamiltonian when both the initial and the product vectors are sparse. As a result of point (i) large disk operations can be skipped which otherwise may be a bottleneck of the procedure. At point (ii) we progress by adopting the implementation of the linear transformation by Olsen et al. [J. Chem Phys. 89, 2185 (1988)] for the sparse case, getting the algorithm applicable to larger systems and faster at the same time. The error of a SFCI calculation depends only on the dropout thresholds for the sparse vectors, and can be tuned by controlling the amount of system memory passed to the procedure. The algorithm permits to perform FCI calculations on single node workstations for systems previously accessible only by supercomputers

  1. Force Concept Inventory-based multiple-choice test for investigating students’ representational consistency

    Directory of Open Access Journals (Sweden)

    Pasi Nieminen

    2010-08-01

    Full Text Available This study investigates students’ ability to interpret multiple representations consistently (i.e., representational consistency in the context of the force concept. For this purpose we developed the Representational Variant of the Force Concept Inventory (R-FCI, which makes use of nine items from the 1995 version of the Force Concept Inventory (FCI. These original FCI items were redesigned using various representations (such as motion map, vectorial and graphical, yielding 27 multiple-choice items concerning four central concepts underpinning the force concept: Newton’s first, second, and third laws, and gravitation. We provide some evidence for the validity and reliability of the R-FCI; this analysis is limited to the student population of one Finnish high school. The students took the R-FCI at the beginning and at the end of their first high school physics course. We found that students’ (n=168 representational consistency (whether scientifically correct or not varied considerably depending on the concept. On average, representational consistency and scientifically correct understanding increased during the instruction, although in the post-test only a few students performed consistently both in terms of representations and scientifically correct understanding. We also compared students’ (n=87 results of the R-FCI and the FCI, and found that they correlated quite well.

  2. Gender Fairness within the Force Concept Inventory

    Science.gov (United States)

    Traxler, Adrienne; Henderson, Rachel; Stewart, John; Stewart, Gay; Papak, Alexis; Lindell, Rebecca

    2018-01-01

    Research on the test structure of the Force Concept Inventory (FCI) has largely ignored gender, and research on FCI gender effects (often reported as "gender gaps") has seldom interrogated the structure of the test. These rarely crossed streams of research leave open the possibility that the FCI may not be structurally valid across…

  3. Mechanical energy yields and pressure volume and pressure time curves for whole core fuel-coolant interactions

    Energy Technology Data Exchange (ETDEWEB)

    Coddington, P [United Kingdom Atomic Energy Authority, Atomic Energy Establishment, Winfrith, Dorchester, Dorset (United Kingdom)

    1979-10-15

    In determining the damage consequences of a whole core Fuel-Coolant Interaction (FCI), one measure of the strength of a FCI that can be used and is independent of the system geometry is the constant volume mixing mechanical yield (often referred to as the Hicks-Menzies yield), which represents a near upper limit to the mechanical work of a FCI. This paper presents a recalculation of the Hicks-Menzies yields for UO{sub 2} and sodium for a range of initial fuel temperatures and fuel to coolant mass ratios, using recently published UO{sub 2} and sodium equation of state data. The work presented here takes a small number of postulated FCIs with as wide range as possible of thermal interaction parameters and determines their pressure-volume P(V) and pressure-time P(t) relations, using geometrical constraints representative of the reactor. Then by examining these P(V) and P(t) curves a representative pressure-relative volume curve or range of possible curves, for use in containment analysis, is recommended

  4. Proceedings of the OECD/CSNI specialists meeting on fuel-coolant interactions

    Energy Technology Data Exchange (ETDEWEB)

    Akiyama, Mamoru; Yamano, Norihiro; Sugimoto, Jun [eds.

    1998-01-01

    The OECD/CSNI Specialists Meeting on Fuel Coolant Interactions (FCI) was held at Tokai-mura in Japan on May 19 through 21, 1997, and attended by 80 participants from 14 countries and one international organizations. In the meeting 36 papers were presented followed by active discussions in six sessions on various aspects of FCI issues, such as reactor application, premixing, propagation/trigger, experiments and code/models. At the end of the Meeting, the participants have reached to the consensus on the summary and recommendations, which consists of the following items; (1) We find no new evidence that would change or violate the conclusion of SERG-2 (1996) that alpha-mode failure is not risk significant. (2) Significant progress has been made since the Santa Barbara meeting (1993). (3) Several areas have been identified, which need further investigations to understand the basic FCI phenomena, and to improve the modeling. (4) We recommend maximizing open communication between various research groups in order to accelerate the resolution of the remaining issues. (5) We recommend that the next specialist meeting be held within 3 to 5 years in order to synthesize the activities described above. (J.P.N.)

  5. Analyzing force concept inventory with item response theory

    Science.gov (United States)

    Wang, Jing; Bao, Lei

    2010-10-01

    Item response theory is a popular assessment method used in education. It rests on the assumption of a probability framework that relates students' innate ability and their performance on test questions. Item response theory transforms students' raw test scores into a scaled proficiency score, which can be used to compare results obtained with different test questions. The scaled score also addresses the issues of ceiling effects and guessing, which commonly exist in quantitative assessment. We used item response theory to analyze the force concept inventory (FCI). Our results show that item response theory can be useful for analyzing physics concept surveys such as the FCI and produces results about the individual questions and student performance that are beyond the capability of classical statistics. The theory yields detailed measurement parameters regarding the difficulty, discrimination features, and probability of correct guess for each of the FCI questions.

  6. Synopsis of the results of ISP-39 on FARO test L-14

    Energy Technology Data Exchange (ETDEWEB)

    Addabbo, C.; Annunziato, A.; Magallon, D. [Commission of the European Communities, Ispra (Italy). Joint Research Center

    1998-01-01

    This paper provides a synopsis of the salient results from the ISP(International Standard Problem)-39 exercise promoted by OECD-CSNI in the frame of the NEA activities aimed at fostering international cooperation in reactor safety research and development. ISP-39 has been conceived to benchmark the predictive capabilities of computer codes used in the evaluation of FCI and quenching phenomenologies of relevance in water cooled reactors severe accidents safety analysis. The ISP-39 reference case is FARO test L-14, a non-energetic FCI test performed in the FARO experimental installation under realistic melt composition and prototypical test conditions. (author)

  7. Facile preparation and enhanced microwave absorption properties of flake carbonyl iron/Fe3O4 composite

    International Nuclear Information System (INIS)

    Min, Dandan; Zhou, Wancheng; Luo, Fa; Zhu, Dongmei

    2017-01-01

    Highlights: • Flake carbonyl iron/Fe 3 O 4 composites were prepared by surface oxidation technique. • Lower permittivity and modest permeability was obtained by the FCI/Fe 3 O 4 composites. • Enhanced absorption efficiency and broader absorption band were obtained. - Abstract: Flake carbonyl iron/Fe 3 O 4 (FCI/Fe 3 O 4 ) composites with enhanced microwave absorption properties were prepared by a direct and flexible surface oxidation technique. The phase structures, morphology, magnetic properties, frequency-dependent electromagnetic and microwave absorption properties of the composites were investigated. The measurement results showed that lower permittivity as well as modest permeability was obtained by the FCI/Fe 3 O 4 composites. The calculated microwave absorption properties indicated that enhanced absorption efficiency and broader absorption band were obtained by the FCI/Fe 3 O 4 composite comparing with the FCI composite. The absorption frequency range with reflection loss (RL) below −5 dB of FCI/Fe 3 O 4 composites at reaction time of 90 min at thickness of 1.5 mm is 13.3 GHz from 4.7 to 18 GHz, while the bandwidth of the FCI composite is only 5.9 GHz from 2.6 to 8.5 GHz at the same thickness. Thus, such absorbers could act as effective and wide broadband microwave absorbers in the GHz range.

  8. Annual report 2000

    International Nuclear Information System (INIS)

    2001-01-01

    This report presents the industrial activities and the financial results of the Framatome group (Framatome-SA) in 2000. and Siemens have merged their nuclear activities and have created Framatome-ANP (advanced nuclear power) owned by Framatome (66%) and Siemens (34%). This new society represents a turnover of 3 millions Euros and a staff of 13.000 employees. In the sector of connectors, FCI (Framatome Connectors International) has reinforced its second position in the world, FCI has enjoyed a high growth in the sector of telecommunication and has created a department dealing with optic fibers. 32% of the activities of Framatome-SA have been performed in France, 26% in North America and 42% in the rest of the world. In 2000 the trading results after having paid taxes reached 306 millions Euros, it represents 6.1% of the turnover. (A.C.)

  9. Annual report 2000; Rapport annuel 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report presents the industrial activities and the financial results of the Framatome group (Framatome-SA) in 2000. and Siemens have merged their nuclear activities and have created Framatome-ANP (advanced nuclear power) owned by Framatome (66%) and Siemens (34%). This new society represents a turnover of 3 millions Euros and a staff of 13.000 employees. In the sector of connectors, FCI (Framatome Connectors International) has reinforced its second position in the world, FCI has enjoyed a high growth in the sector of telecommunication and has created a department dealing with optic fibers. 32% of the activities of Framatome-SA have been performed in France, 26% in North America and 42% in the rest of the world. In 2000 the trading results after having paid taxes reached 306 millions Euros, it represents 6.1% of the turnover. (A.C.)

  10. Dividing the Force Concept Inventory into two equivalent half-length tests

    Directory of Open Access Journals (Sweden)

    Jing Han

    2015-05-01

    Full Text Available The Force Concept Inventory (FCI is a 30-question multiple-choice assessment that has been a building block for much of the physics education research done today. In practice, there are often concerns regarding the length of the test and possible test-retest effects. Since many studies in the literature use the mean score of the FCI as the primary variable, it would be useful then to have different shorter tests that can produce FCI-equivalent scores while providing the benefits of being quicker to administer and overcoming the test-retest effects. In this study, we divide the 1995 version of the FCI into two half-length tests; each contains a different subset of the original FCI questions. The two new tests are shorter, still cover the same set of concepts, and produce mean scores equivalent to those of the FCI. Using a large quantitative data set collected at a large midwestern university, we statistically compare the assessment features of the two half-length tests and the full-length FCI. The results show that the mean error of equivalent scores between any two of the three tests is within 3%. Scores from all tests are well correlated. Based on the analysis, it appears that the two half-length tests can be a viable option for score based assessment that need to administer tests quickly or need to measure short-term gains where using identical pre- and post-test questions is a concern.

  11. Facile preparation and enhanced microwave absorption properties of flake carbonyl iron/Fe{sub 3}O{sub 4} composite

    Energy Technology Data Exchange (ETDEWEB)

    Min, Dandan, E-mail: mdd4776@126.com; Zhou, Wancheng; Luo, Fa; Zhu, Dongmei

    2017-08-01

    Highlights: • Flake carbonyl iron/Fe{sub 3}O{sub 4} composites were prepared by surface oxidation technique. • Lower permittivity and modest permeability was obtained by the FCI/Fe{sub 3}O{sub 4} composites. • Enhanced absorption efficiency and broader absorption band were obtained. - Abstract: Flake carbonyl iron/Fe{sub 3}O{sub 4} (FCI/Fe{sub 3}O{sub 4}) composites with enhanced microwave absorption properties were prepared by a direct and flexible surface oxidation technique. The phase structures, morphology, magnetic properties, frequency-dependent electromagnetic and microwave absorption properties of the composites were investigated. The measurement results showed that lower permittivity as well as modest permeability was obtained by the FCI/Fe{sub 3}O{sub 4} composites. The calculated microwave absorption properties indicated that enhanced absorption efficiency and broader absorption band were obtained by the FCI/Fe{sub 3}O{sub 4} composite comparing with the FCI composite. The absorption frequency range with reflection loss (RL) below −5 dB of FCI/Fe{sub 3}O{sub 4} composites at reaction time of 90 min at thickness of 1.5 mm is 13.3 GHz from 4.7 to 18 GHz, while the bandwidth of the FCI composite is only 5.9 GHz from 2.6 to 8.5 GHz at the same thickness. Thus, such absorbers could act as effective and wide broadband microwave absorbers in the GHz range.

  12. Frequency of consuming foods predicts changes in cravings for those foods during weight loss: The POUNDS Lost Study

    Science.gov (United States)

    Apolzan, John W.; Myers, Candice A.; Champagne, Catherine M.; Beyl, Robbie A.; Raynor, Hollie A.; Anton, Stephen A.; Williamson, Donald A.; Sacks, Frank M.; Bray, George A.; Martin, Corby K.

    2017-01-01

    Objective Food cravings are thought to be the result of conditioning or pairing hunger with consumption of certain foods. Methods In a two-year weight loss trial, subjects were randomized to one of four diets that varied in macronutrient content. The Food Craving Inventory (FCI) was used to measure cravings at baseline, 6, and 24 months. Also, food intake was measured at those time points. To measure free-living consumption of food items measured in the FCI, items on the FCI were matched to the foods consumed from the food intake assessments. Secondarily, we analyzed the amount of food consumed on food intake assessments from foods on the FCI. Results 367 subjects who were overweight and obese were included. There was an association between change from baseline FCI item consumption and change in cravings at months 6 (p<0.001) and 24 (p<0.05). There was no association between change from baseline amount of energy consumed per FCI item and change in cravings. Conclusions Altering frequency of consuming craved foods is positively associated with cravings; however, changing the amount of foods consumed does not appear to alter cravings. These results support the conditioning model of food cravings and provide guidance on how to reduce food cravings. PMID:28618170

  13. Nanoscale multireference quantum chemistry: full configuration interaction on graphical processing units.

    Science.gov (United States)

    Fales, B Scott; Levine, Benjamin G

    2015-10-13

    Methods based on a full configuration interaction (FCI) expansion in an active space of orbitals are widely used for modeling chemical phenomena such as bond breaking, multiply excited states, and conical intersections in small-to-medium-sized molecules, but these phenomena occur in systems of all sizes. To scale such calculations up to the nanoscale, we have developed an implementation of FCI in which electron repulsion integral transformation and several of the more expensive steps in σ vector formation are performed on graphical processing unit (GPU) hardware. When applied to a 1.7 × 1.4 × 1.4 nm silicon nanoparticle (Si72H64) described with the polarized, all-electron 6-31G** basis set, our implementation can solve for the ground state of the 16-active-electron/16-active-orbital CASCI Hamiltonian (more than 100,000,000 configurations) in 39 min on a single NVidia K40 GPU.

  14. Analyzing false positives of four questions in the Force Concept Inventory

    Science.gov (United States)

    Yasuda, Jun-ichiro; Mae, Naohiro; Hull, Michael M.; Taniguchi, Masa-aki

    2018-06-01

    In this study, we analyze the systematic error from false positives of the Force Concept Inventory (FCI). We compare the systematic errors of question 6 (Q.6), Q.7, and Q.16, for which clearly erroneous reasoning has been found, with Q.5, for which clearly erroneous reasoning has not been found. We determine whether or not a correct response to a given FCI question is a false positive using subquestions. In addition to the 30 original questions, subquestions were introduced for Q.5, Q.6, Q.7, and Q.16. This modified version of the FCI was administered to 1145 university students in Japan from 2015 to 2017. In this paper, we discuss our finding that the systematic errors of Q.6, Q.7, and Q.16 are much larger than that of Q.5 for students with mid-level FCI scores. Furthermore, we find that, averaged over the data sample, the sum of the false positives from Q.5, Q.6, Q.7, and Q.16 is about 10% of the FCI score of a midlevel student.

  15. An assessment of ex-vessel fuel-coolant interaction energetics for advanced light water reactors

    International Nuclear Information System (INIS)

    Murphy, J.G.; Corradini, M.L.

    1997-01-01

    The occurrence of an energetic fuel/coolant interaction (FCI) below the reactor pressure vessel in the cavity of advanced light water reactors (ALWRs) are analyzed to determine the possible hazard to structural walls as a result of dynamic liquid phase pressures. Such analyses are important to demonstrate that these cavity walls will maintain their integrity so that ex-vessel core debris coolability is possible. Past studies that have examined this or related issues are reviewed, and a methodology is proposed to analyze the occurrence of this physical event using the IFCI and TEXAS models for the FCI as well as dynamic shock wave propagation estimates using hand calculations as well as the CTH hydro model. Scenarios for the ALWRs are reviewed, and one severe accident scenario is used as an example to demonstrate the methodology. Such methodologies are recommended for consideration in future safety studies. These methodologies should be verified with direct comparison to energetic FCI data such as that being produced in KROTOS at the Joint Research Centre, Ispra

  16. An investigation on the material effect on the result of fuel coolant interactions in the TROI experiments

    International Nuclear Information System (INIS)

    Park, I. K.; Kim, J. H.; Min, B. T.; Hong, S. W.

    2008-01-01

    One of the findings from the TROI experiments is that the results of the fuel coolant interaction (FCI) are strongly dependent on the composition of the corium, which is composed of UO 2 , ZrO 2 , Zr, steel. TEXAS- V simulation for the TROI experiments indicated that a relatively low void fraction seems to have resulted in a strong steam explosion and the low voided mixture must be induced by big size particles. The particle sizes of the non-explosive TROI tests were analyzed because the explosive tests do not represent the particles during mixing. It indicates that the debris size seems to reflect the material difference, and the trend is the same as the debris size in the TEXAS-V simulation. TEXAS-V calculation for the alumina/water system indicates that the conductivity is also related to the material effect on the FCI result. The heat loss evaluation using a single sphere film boiling model shows that a reasonable conductivity and particle size give a reliable estimation for the FCI result. Thus reliable values for the physical properties such as the surface tension and a better understanding for the breakup process would be necessary for a more convincible nuclear safety analysis. (authors)

  17. Identification of relevant conditions and experiments for fuel-coolant interactions in nuclear power plants - SERENA Co-ordinated Programme (Steam Explosion Resolution for Nuclear Applications) Phase 1, Task 1 - Final report

    International Nuclear Information System (INIS)

    Magallon, D.; Scott de Martinville, E.; Chaumont, B.; Filippi, M.; Meignen, R.; Berthoud, G.; Ratel, G.; Melikhov, O.I.; Melikhov, V.I.; Jacobs, H.; Buerger, Manfred; Buck, Michael; Moriyama, K.; Nakamura, H.; Hirano, M.; Muramatsu, K.; Ishikawa, J.; Song, Jinho; Bang, Kwanghyun; Suh, Namduk; Sairanen, Risto; Lindholm, Ilona

    2004-01-01

    SERENA (Steam Explosion Resolution for Nuclear Applications) is an international OECD programme for the resolution of FCI remaining issues. The programme has origin the concerns expressed by the Senior Group Experts on Nuclear Safety Research and Programme (SESAR/FAP) about de-emphasis of FCI research all over the world, while uncertainties still exist on some aspects of FCI. After an evaluation of remaining needs by FCI experts in a meeting October 2000, a proposal was matured during 2001 following CSNI recommendations that existing knowledge should be carefully assessed before carrying out new experiments, and reactor application should be the focus of any new action. The work programme was approved by CSNI December 2001. The programme started January 2002. The overall objective of SERENA is to obtain convergence on the understanding of FCI processes and energetics, as well as on method(s) for reliable estimate of the magnitude of loadings for realistic reactor conditions, in order to bring understanding and predictability of FCI energetics to desirable levels for risk management. The work is performed in two phases: - Phase 1 analyses and evaluates knowledge and data on FCI by using available tools with the aim to identify areas where large uncertainties/ discrepancies still subsist and are important for predicting loads in reactors with a sufficient level of confidence, and work to be done, if any, to reduce these uncertainties/discrepancies. - Phase 2 will implement analytical and experimental actions to resolve these uncertainties/ discrepancies, if required. The objective of Phase 1 is reached through comparative calculations by available tools of existing experiments and reactor cases. It is divided into five tasks: 1. Identification of relevant conditions for FCI in reactor, 2. Comparison of various approaches for calculating jet break-up and pre-mixing, 3. Comparison of various approaches for calculating the explosion phase, 4. Reactor applications, 5

  18. Rasch model based analysis of the Force Concept Inventory

    Directory of Open Access Journals (Sweden)

    Maja Planinic

    2010-03-01

    Full Text Available The Force Concept Inventory (FCI is an important diagnostic instrument which is widely used in the field of physics education research. It is therefore very important to evaluate and monitor its functioning using different tools for statistical analysis. One of such tools is the stochastic Rasch model, which enables construction of linear measures for persons and items from raw test scores and which can provide important insight in the structure and functioning of the test (how item difficulties are distributed within the test, how well the items fit the model, and how well the items work together to define the underlying construct. The data for the Rasch analysis come from the large-scale research conducted in 2006-07, which investigated Croatian high school students’ conceptual understanding of mechanics on a representative sample of 1676 students (age 17–18 years. The instrument used in research was the FCI. The average FCI score for the whole sample was found to be (27.7±0.4%, indicating that most of the students were still non-Newtonians at the end of high school, despite the fact that physics is a compulsory subject in Croatian schools. The large set of obtained data was analyzed with the Rasch measurement computer software WINSTEPS 3.66. Since the FCI is routinely used as pretest and post-test on two very different types of population (non-Newtonian and predominantly Newtonian, an additional predominantly Newtonian sample (N=141, average FCI score of 64.5% of first year students enrolled in introductory physics course at University of Zagreb was also analyzed. The Rasch model based analysis suggests that the FCI has succeeded in defining a sufficiently unidimensional construct for each population. The analysis of fit of data to the model found no grossly misfitting items which would degrade measurement. Some items with larger misfit and items with significantly different difficulties in the two samples of students do require further

  19. Social power and approach-related neural activity.

    Science.gov (United States)

    Boksem, Maarten A S; Smolders, Ruud; De Cremer, David

    2012-06-01

    It has been argued that power activates a general tendency to approach whereas powerlessness activates a tendency to inhibit. The assumption is that elevated power involves reward-rich environments, freedom and, as a consequence, triggers an approach-related motivational orientation and attention to rewards. In contrast, reduced power is associated with increased threat, punishment and social constraint and thereby activates inhibition-related motivation. Moreover, approach motivation has been found to be associated with increased relative left-sided frontal brain activity, while withdrawal motivation has been associated with increased right sided activations. We measured EEG activity while subjects engaged in a task priming either high or low social power. Results show that high social power is indeed associated with greater left-frontal brain activity compared to low social power, providing the first neural evidence for the theory that high power is associated with approach-related motivation. We propose a framework accounting for differences in both approach motivation and goal-directed behaviour associated with different levels of power.

  20. Using module analysis for multiple choice responses

    DEFF Research Database (Denmark)

    Brewe, Eric; Bruun, Jesper; Bearden, Ian

    2016-01-01

    We describe a methodology for carrying out a network analysis of Force Concept Inventory (FCI) responses that aims to identify communities of incorrect responses. This method first treats FCI responses as a bipartite, student X response, network. We then use Locally Adaptive Network Sparsificatio...

  1. Personality types and student performance in an introductory physics course

    Science.gov (United States)

    Harlow, Jason J. B.; Harrison, David M.; Justason, Michael; Meyertholen, Andrew; Wilson, Brian

    2017-12-01

    We measured the personality type of the students in a large introductory physics course of mostly life science students using the True Colors instrument. We found large correlations of personality type with performance on the precourse Force Concept Inventory (FCI), both term tests, the postcourse FCI, and the final examination. We also saw correlations with the normalized gain on the FCI. The personality profile of the students in this course is very different from the profile of the physics faculty and graduate students, and also very different from the profile of students taking the introductory physics course intended for physics majors and specialists.

  2. Advantages of flow cytometry immunophenotyping for the diagnosis of central nervous system non-Hodgkin's lymphoma in AIDS patients.

    Science.gov (United States)

    Subirá, D; Górgolas, M; Castañón, S; Serrano, C; Román, A; Rivas, F; Tomás, J F

    2005-01-01

    Neurological disorders are common in HIV-infected patients. Central nervous system (CNS) lymphoma should always be considered because it is an important cause of morbidity and mortality. To investigate the clinical utility of flow cytometry immunophenotyping (FCI) in diagnosing or discarding leptomeningeal involvement in HIV-infected patients and to compare its sensitivity with that of conventional cytological methods. Fifty-six cerebrospinal fluid (CSF) samples from 29 HIV-infected patients were independently evaluated by flow cytometry and cytology. The description of an aberrant immunophenotype was the criterion used to define the malignant nature of any CSF cell population. FCI and cytology gave concordant results for 48 of the 56 CSF samples studied: 37 were negative for malignancy and 11 had evidence of CNS lymphoma. Discordant results were obtained for eight CSF samples, and the accuracy of the FCI findings could be demonstrated for four CSF samples described as positive for malignancy according to the FCI criteria. A high level of agreement was found between the results obtained using the two methods, but FCI gave at least 25% higher sensitivity than conventional cytomorphological methods for the detection of malignant cells. This advantage suggests that, in case of negative flow cytometry results, disorders other than non-Hodgkin's lymphoma should be strongly considered.

  3. The flux-coordinate independent approach applied to X-point geometries

    International Nuclear Information System (INIS)

    Hariri, F.; Hill, P.; Ottaviani, M.; Sarazin, Y.

    2014-01-01

    A Flux-Coordinate Independent (FCI) approach for anisotropic systems, not based on magnetic flux coordinates, has been introduced in Hariri and Ottaviani [Comput. Phys. Commun. 184, 2419 (2013)]. In this paper, we show that the approach can tackle magnetic configurations including X-points. Using the code FENICIA, an equilibrium with a magnetic island has been used to show the robustness of the FCI approach to cases in which a magnetic separatrix is present in the system, either by design or as a consequence of instabilities. Numerical results are in good agreement with the analytic solutions of the sound-wave propagation problem. Conservation properties are verified. Finally, the critical gain of the FCI approach in situations including the magnetic separatrix with an X-point is demonstrated by a fast convergence of the code with the numerical resolution in the direction of symmetry. The results highlighted in this paper show that the FCI approach can efficiently deal with X-point geometries

  4. Massive weight loss decreases corticosteroid-binding globulin levels and increases free cortisol in healthy obese patients: an adaptive phenomenon?

    Science.gov (United States)

    Manco, Melania; Fernández-Real, José M; Valera-Mora, Maria E; Déchaud, Henri; Nanni, Giuseppe; Tondolo, Vincenzo; Calvani, Menotti; Castagneto, Marco; Pugeat, Michel; Mingrone, Geltrude

    2007-06-01

    Obesity, insulin resistance, and weight loss have been associated with changes in hypothalamic-pituitary-adrenal (HPA) axis. So far, no conclusive data relating to this association are available. In this study, we aim to investigate the effects of massive weight loss on cortisol suppressibility, cortisol-binding globulin (CBG), and free cortisol index (FCI) in formerly obese women. Ten glucose-normotolerant, fertile, obese women (BMI >40 kg/m2, aged 38.66 +/- 13.35 years) were studied before and 2 years after biliopancreatic diversion (BPD) when stable weight was achieved and were compared with age-matched healthy volunteers. Cortisol suppression was evaluated by a 4-mg intravenous dexamethasone suppression test (DEX-ST). FCI was calculated as the cortisol-to-CBG ratio. Insulin sensitivity was measured by an euglycemic-hyperinsulinemic clamp, and insulin secretion was measured by a C-peptide deconvolution method. No difference was found in cortisol suppression after DEX-ST before or after weight loss. A decrease in ACTH was significantly greater in control subjects than in obese (P = 0.05) and postobese women (P obese subjects, an increase of free cortisol was associated with a simultaneous decrease in CBG levels, which might be an adaptive phenomenon relating to environmental changes. This topic, not addressed before, adds new insight into the complex mechanisms linking HPA activity to obesity.

  5. Performance of different metrics proposed to CIE TC 1-91

    Directory of Open Access Journals (Sweden)

    Pramod Bhusal

    2017-12-01

    Full Text Available The main aim of the article is to find out the performance of different metrics proposed to CIE TC 1-91. Currently, six different indexes have been proposed to CIE TC 1-91: Colour Quality Scale (CQS, Feeling of Contrast Index (FCI, Memory colour rendering index (MCRI, Preference of skin (PS, Relative gamut area index (RGAI and Illuminating Engineering society Method for evaluating light source colour rendition (IES TM-30. The evaluation and analysis are based on previously conducted experiment in lighting booth. The analysis showed the area based metric FCI was good subjective preference indicator. The subjective preference was measured in terms of naturalness of objects, colourfulness of colour checker chart, and the visual appearance of the lit scene in the booth.

  6. Cookbook Procedures in MBL Physics Exercises.

    Science.gov (United States)

    Royuk, Brent; Brooks, David W.

    2003-01-01

    Presents results of a controlled experiment comparing the conceptual mechanics learning gains as measured by the Force Concept Inventory (FCI) between two laboratory groups. One group completed cookbook labs while the other completed Interactive-Engagement (IE) labs in RealTime Physics. Suggests that laboratory activities should engage students in…

  7. The origin and magnitude of pressures in fuel-coolant interactions

    International Nuclear Information System (INIS)

    Heer, W.; Jakeman, D.; Smith, B.L.

    1987-01-01

    A number of small scale experiments to simulate fuel coolant interaction (FCI) effects have been carried out using Freon and water. Contrary to the predictions of most current FCI models, only modest pressure transients are observed within the interaction region itself but large pressure spikes, near to or above critical Freon pressure, are seen at the boundaries of the region. Similar pressure amplification effects have been noticed in parallel experiments involving two phase mixtures. It is suggested that in both cases a water hammer type effect is the cause of the pressure spikes. These observations could form the basis of new thinking in FCI modelling. (author)

  8. Marine Biology Activities. Ocean Related Curriculum Activities.

    Science.gov (United States)

    Pauls, John

    The ocean affects all of our lives. Therefore, awareness of and information about the interconnections between humans and oceans are prerequisites to making sound decisions for the future. Project ORCA (Ocean Related Curriculum Activities) has developed interdisciplinary curriculum materials designed to meet the needs of students and teachers…

  9. Social power and approach-related neural activity

    OpenAIRE

    Boksem, Maarten; Smolders, Ruud; Cremer, David

    2009-01-01

    textabstractIt has been argued that power activates a general tendency to approach whereas powerlessness activates a tendency to inhibit. The assumption is that elevated power involves reward-rich environments, freedom and, as a consequence, triggers an approach-related motivational orientation and attention to rewards. In contrast, reduced power is associated with increased threat, punishment and social constraint and thereby activates inhibition-related motivation. Moreover, approach motiva...

  10. Gender fairness within the Force Concept Inventory

    Science.gov (United States)

    Traxler, Adrienne; Henderson, Rachel; Stewart, John; Stewart, Gay; Papak, Alexis; Lindell, Rebecca

    2018-01-01

    Research on the test structure of the Force Concept Inventory (FCI) has largely ignored gender, and research on FCI gender effects (often reported as "gender gaps") has seldom interrogated the structure of the test. These rarely crossed streams of research leave open the possibility that the FCI may not be structurally valid across genders, particularly since many reported results come from calculus-based courses where 75% or more of the students are men. We examine the FCI considering both psychometrics and gender disaggregation (while acknowledging this as a binary simplification), and find several problematic questions whose removal decreases the apparent gender gap. We analyze three samples (total Npre=5391 , Npost=5769 ) looking for gender asymmetries using classical test theory, item response theory, and differential item functioning. The combination of these methods highlights six items that appear substantially unfair to women and two items biased in favor of women. No single physical concept or prior experience unifies these questions, but they are broadly consistent with problematic items identified in previous research. Removing all significantly gender-unfair items halves the gender gap in the main sample in this study. We recommend that instructors using the FCI report the reduced-instrument score as well as the 30-item score, and that credit or other benefits to students not be assigned using the biased items.

  11. Comparison between the performance of some KEK-klystrons and simulation results

    Energy Technology Data Exchange (ETDEWEB)

    Fukuda, Shigeki [National Lab. for High Energy Physics, Tsukuba, Ibaraki (Japan)

    1997-04-01

    Recent developments of various klystron simulation codes have enabled us to realistically design klystrons. This paper presents various simulation results using the FCI code and the performances of tubes manufactured based on this code. Upgrading a 30-MW S-band klystron and developing a 50-MW S-band klystron for the KEKB projects are successful examples based on FCI-code predictions. Mass-productions of these tubes have already started. On the other hand, a discrepancy has been found between the FCI simulation results and the performance of real tubes. In some cases, the simulation results lead to high-efficiency results, while manufactured tubes show the usual value, or a lower value, of the efficiency. One possible cause may come from a data mismatch between the electron-gun simulation and the input data set of the FCI code for the gun region. This kind of discrepancy has been observed in 30-MW S-band pulsed tubes, sub-booster pulsed tubes and L-band high-duty pulsed klystrons. Sometimes, JPNDSK (one-dimensional disk-model code) gives similar results. Some examples using the FCI code are given in this article. An Arsenal-MSU code could be applied to the 50-MW klystron under collaboration with Moscow State University; a good agreement has been found between the prediction of the code and performance. (author)

  12. Gender fairness within the Force Concept Inventory

    Directory of Open Access Journals (Sweden)

    Adrienne Traxler

    2018-01-01

    Full Text Available Research on the test structure of the Force Concept Inventory (FCI has largely ignored gender, and research on FCI gender effects (often reported as “gender gaps” has seldom interrogated the structure of the test. These rarely crossed streams of research leave open the possibility that the FCI may not be structurally valid across genders, particularly since many reported results come from calculus-based courses where 75% or more of the students are men. We examine the FCI considering both psychometrics and gender disaggregation (while acknowledging this as a binary simplification, and find several problematic questions whose removal decreases the apparent gender gap. We analyze three samples (total N_{pre}=5391, N_{post}=5769 looking for gender asymmetries using classical test theory, item response theory, and differential item functioning. The combination of these methods highlights six items that appear substantially unfair to women and two items biased in favor of women. No single physical concept or prior experience unifies these questions, but they are broadly consistent with problematic items identified in previous research. Removing all significantly gender-unfair items halves the gender gap in the main sample in this study. We recommend that instructors using the FCI report the reduced-instrument score as well as the 30-item score, and that credit or other benefits to students not be assigned using the biased items.

  13. Status of ANL out-of-pile investigations of severe accident phenomena for liquid metal reactors

    International Nuclear Information System (INIS)

    Spencer, B.W.; Marchaterre, J.F.; Anderson, R.P.

    1986-01-01

    Research addressing LMFBR whole core accidents has been terminated, and there is now emphasis on quantifying reactivity feedbacks, and in particular enhancing negative feedback, so that advanced LMR designs will provide inherently safe operation. The status of recent HCDA-related laboratory research performed at ANL, up to the time that such activities were no longer needed to support CRBR licensing, is described. Included are descriptions of programs addressing sodium channel voiding, fuel sweepout, fuel dispersal and plugging, boiled-up pool, UO 2 /sodium FCI, and debris coolability. Descriptions of recent investigations involving the metal fuel/sodium system are also included

  14. Influence of thermal performance on design parameters of a He/LiPb dual coolant DEMO concept blanket design

    Energy Technology Data Exchange (ETDEWEB)

    Mas de les Valls, E., E-mail: elisabet.masdelesvalls@gits.ws [Technical University of Catalonia (UPC), Jordi Girona 1-3, 08034 Barcelona (Spain); Technology for Fusion (T4F) Research Group, GREENER, Department of Heat Engines, Barcelona (Spain); Batet, L. [Technical University of Catalonia (UPC), Jordi Girona 1-3, 08034 Barcelona (Spain); Technology for Fusion (T4F) Research Group, GREENER, Department of Physics and Nuclear Engineering, Barcelona (Spain); Medina, V. de [Technical University of Catalonia (UPC), Jordi Girona 1-3, 08034 Barcelona (Spain); Sediment Transport Research Group, Department of Engineering Hydraulic, Marine and Environmental Engineering, Barcelona (Spain); Fradera, J. [Technical University of Catalonia (UPC), Jordi Girona 1-3, 08034 Barcelona (Spain); Technology for Fusion (T4F) Research Group, GREENER, Department of Physics and Nuclear Engineering, Barcelona (Spain); Sanmarti, M. [bFUS-IREC, Jardins de les Dones de Negre 1, 08930 Sant Adria del Besos (Spain); Sedano, L.A. [EURATOM-CIEMAT Association, 28040 Madrid (Spain)

    2012-08-15

    Spanish Breeding Blanket Technology Programme TECNO{sub F}US is exploring the technological capabilities of a Dual-Coolant He/Pb15.7Li breeding blanket for DEMO and studying new breeding blanket design specifications. The progress of the channel conceptual design is being conducted in parallel with the extension of MHD computational capabilities of CFD tools and the underlying physics of MHD models. A qualification of MHD effects under present blanket design specifications and some approaches to their modelling were proposed by the authors in . The analysis was accomplished with the 2D transient algorithm from Sommeria and Moreau and implemented in the OpenFOAM CFD toolbox . The thermal coupling was implemented by means of the Boussinesq hypothesis. Previous analyses showed the need of improvement of FCI thickness and thermal properties in order to obtain a desirable liquid metal temperature gain of 300 Degree-Sign C. In the present study, an assessment through sensitivity and parametric analyses of the required FCI thickness is performed. Numerical simulations have been carried out considering a Robin-type thermal boundary condition which assumes 1D steady state thermal balance across the solid FCI and Eurofer layers. Such boundary condition has been validated with a fluid-solid coupled domain analysis. Results for the studied flow conditions and channel dimensions show that, in order to obtain a liquid metal temperature gain of about 300 Degree-Sign C, the required FCI material should have a very small effective heat transfer coefficient ((k/{delta}) {<=} 1 W/m{sup 2}K) and fluid velocities should be about 0.2 m/s or less. Moreover, special attention has to be placed on the temperature difference across the FCI layer. However, for a maximised liquid metal thermal gain, higher velocities would be preferable, what would also imply a reduced temperature difference across the FCI layer.

  15. Vortex-dislodged cells from bone marrow trephine biopsy yield satisfactory results for flow cytometric immunophenotyping.

    Science.gov (United States)

    Bommannan, K; Sachdeva, M U S; Gupta, M; Bose, P; Kumar, N; Sharma, P; Naseem, S; Ahluwalia, J; Das, R; Varma, N

    2016-10-01

    A good bone marrow (BM) sample is essential in evaluating many hematologic disorders. An unsuccessful BM aspiration (BMA) procedure precludes a successful flow cytometric immunophenotyping (FCI) in most hematologic malignancies. Apart from FCI, most ancillary diagnostic techniques in hematology are less informative. We describe the feasibility of FCI in vortex-dislodged cell preparation obtained from unfixed trephine biopsy (TB) specimens. In pancytopenic patients and dry tap cases, routine diagnostic BMA and TB samples were complemented by additional trephine biopsies. These supplementary cores were immediately transferred into sterile tubes filled with phosphate-buffered saline, vortexed, and centrifuged. The cell pellet obtained was used for flow cytometric immunophenotyping. Of 7955 BMAs performed in 42 months, 34 dry tap cases were eligible for the study. Vortexing rendered a cell pellet in 94% of the cases (32 of 34), and FCI rendered a rapid diagnosis in 100% of the cases (32 of 32) where cell pellets were available. We describe an efficient procedure which could be effectively utilized in resource-limited centers and reduce the frequency of repeat BMA procedures. © 2016 John Wiley & Sons Ltd.

  16. The distribution of plutonium, americium and curium isotopes in pond and stream sediments of the Savannah River Plant, South Carolina, USA

    International Nuclear Information System (INIS)

    Alberts, J.J.; Halverson, J.E.; Orlandini, K.A.

    1986-01-01

    The concentrations of 238 Pu, 239 , 240 Pu, 241 Am and 244 Cm were determined in sediment samples from five streams and two ponds on the Savannah River Plant (SRP) and in four sediment samples from the Savannah River above and below the plant site. The following concentration ranges were determined: 238 Pu, 0.07-386 fCi g -1 ; 239 , 240 Pu, 0.37-1410 fCi g -1 ; 241 Am, 0.1-4360 fCi g -1 ; 244 Cm, -1 . Comparisons of the elemental and isotopic ratios of the sediments show that the majority of the sediments studied have been impacted upon by plant operations and that sediments outside the plant boundary in the Savannah River have only been influenced by aerial releases. Atom ratios of 240 Pu/ 239 Pu indicate that up to 86% of the Pu in these sediments is derived from plant operations. However, comparisons of the concentration data with values for other impacted sediments near nuclear facilities indicate that the levels are relatively small. Finally, <13% of the Pu, Am or Cm in pond sediments is associated with humic or fulvic acids, indicating that little of the material should be remobilized in oxic environments through organic complexation. (author)

  17. Neural activation in stress-related exhaustion

    DEFF Research Database (Denmark)

    Gavelin, Hanna Malmberg; Neely, Anna Stigsdotter; Andersson, Micael

    2017-01-01

    The primary purpose of this study was to investigate the association between burnout and neural activation during working memory processing in patients with stress-related exhaustion. Additionally, we investigated the neural effects of cognitive training as part of stress rehabilitation. Fifty...... association between burnout level and working memory performance was found, however, our findings indicate that frontostriatal neural responses related to working memory were modulated by burnout severity. We suggest that patients with high levels of burnout need to recruit additional cognitive resources...... to uphold task performance. Following cognitive training, increased neural activation was observed during 3-back in working memory-related regions, including the striatum, however, low sample size limits any firm conclusions....

  18. Dividing the Force Concept Inventory into Two Equivalent Half-Length Tests

    Science.gov (United States)

    Han, Jing; Bao, Lei; Chen, Li; Cai, Tianfang; Pi, Yuan; Zhou, Shaona; Tu, Yan; Koenig, Kathleen

    2015-01-01

    The Force Concept Inventory (FCI) is a 30-question multiple-choice assessment that has been a building block for much of the physics education research done today. In practice, there are often concerns regarding the length of the test and possible test-retest effects. Since many studies in the literature use the mean score of the FCI as the…

  19. Meteosat third generation imager: simulation of the flexible combined imager instrument chain

    Science.gov (United States)

    Just, Dieter; Gutiérrez, Rebeca; Roveda, Fausto; Steenbergen, Theo

    2014-10-01

    The Meteosat Third Generation (MTG) Programme is the next generation of European geostationary meteorological systems. The first MTG satellite, MTG-I1, which is scheduled for launch at the end of 2018, will host two imaging instruments: the Flexible Combined Imager (FCI) and the Lightning Imager. The FCI will provide continuation of the SEVIRI imager operations on the current Meteosat Second Generation satellites (MSG), but with an improved spatial, temporal and spectral resolution, not dissimilar to GOES-R (of NASA/NOAA). Unlike SEVIRI on the spinning MSG spacecraft, the FCI will be mounted on a 3-axis stabilised platform and a 2-axis tapered scan will provide a full coverage of the Earth in 10 minute repeat cycles. Alternatively, a rapid scanning mode can cover smaller areas, but with a better temporal resolution of up to 2.5 minutes. In order to assess some of the data acquisition and processing aspects which will apply to the FCI, a simplified end-to-end imaging chain prototype was set up. The simulation prototype consists of four different functional blocks: - A function for the generation of FCI-like references images - An image acquisition simulation function for the FCI Line-of-Sight calculation and swath generation - A processing function that reverses the swath generation process by rectifying the swath data - An evaluation function for assessing the quality of the processed data with respect to the reference images This paper presents an overview of the FCI instrument chain prototype, covering instrument characteristics, reference image generation, image acquisition simulation, and processing aspects. In particular, it provides in detail the description of the generation of references images, highlighting innovative features, but also limitations. This is followed by a description of the image acquisition simulation process, and the rectification and evaluation function. The latter two are described in more detail in a separate paper. Finally, results

  20. (JASR) VOL. 10, No. 2, 2010 84 ECONOMIC ANALYSIS OF FARM ...

    African Journals Online (AJOL)

    oma

    fact that they are the major producers of plantain in the state. Four communities ... According to him, the inequality of income between the rural ... result is that women are mainly involved in the marketing activities of plantain in the study area. .... Marketing of Rice, Food Corporation of India (FCI): State Agricultural Marketing.

  1. Research report on design allowable values of structural materials for LMFBR

    International Nuclear Information System (INIS)

    1978-11-01

    The present report is composed of following two main parts. i) review and re-evaluation on test results by FCI Sub-committee studies, performed from 1973 to 1976, ii) review on procedures for determining design allowable values of structural materials for LMFBR components. Re-evaluation works have been made on monotonic tensile properties at elevated temperatures, creep and creep rupture properties, creep-fatigue properties (strain rate and tensile strain hold time effects on strain fatigue properties at elevated temperatures) of Types 316 and 304 stainless steel and 2 1/4Cr-1Mo steel (base and weld metals) produced in Japan. In the first half of the present report, creep-fatigue test results obtained by FCI Sub-committee studies are subjected to re-evaluation by the present P-FCI Sub-committee. Reviews have been made on testing methods on FCI's-creep-fatigue experiments with other test data of the test materials; high temperature monotonic tensile data, creep and creep rupture data, and origin of the test materials. The data of FCI studies are compared with other reference data obtained by several Japanese laboratories. In the latter half of the present report, procedures including ASME's are reviewed for setting design allowable values for LMFBR components on the basis of high temperature strength properties obtained with materials produced in Japan. A creep rupture data of Japanese steels are issued and examined to make proposal for a design allowable stress of S sub(t) through parameter survey. (author)

  2. The role of public relations activities in hospital choice.

    Science.gov (United States)

    Tengilimoglu, Dilaver; Yesiltas, Mehmet; Kisa, Adnan; Dziegielewski, Sophia F

    2007-01-01

    Public relations activities for all organizations can have an important effect on consumer decision-making when buying goods or services. This study examines the effect that public relations activities can have regarding consumer decisions and choice. To explore exemplify this relationship a questionnaire was given to 971 patients within public, university and private hospitals in Ankara, Turkey. Study results show that public relations activities were a crucial factor in determining consumer hospital choice. The majority of respondents reported that the behaviors and attitude of personnel as public relations activities that support the hospital's reputation within the public were the primary variables in hospital choice. Health care managers can use these findings to further understand how patients make informed choices related to usage of a health care facility and to develop and/or improve public relations activities.

  3. Disentangling longitudinal relations between physical activity, work-related fatigue, and task demands

    NARCIS (Netherlands)

    Vries, J.D. de; Claessens, B.J.C.; Hooff, M.L.M. van; Geurts, S.A.E.; Bossche, S.N.J. van den; Kompier, A.J.

    2016-01-01

    Purpose This longitudinal study examined ‘normal’, ‘reversed’, and ‘reciprocal’ relationships between (1) physical activity and work-related fatigue; and (2) physical activity and task demands. Furthermore, the effects of across-time change in meaningful physical activity groups on levels of

  4. Activity-related parenting practices: development of the Parenting Related to Activity Measure (PRAM) and links with mothers' eating psychopathology and compulsive exercise beliefs.

    Science.gov (United States)

    Haycraft, Emma; Powell, Faye; Meyer, Caroline

    2015-01-01

    This is a two-study paper that developed a measure to assess parenting practices related to children's physical activity and explored maternal predictors of such parenting practices. Study 1: A self-report measure of parents' activity-related practices (the Parenting Related to Activity Measure) was developed, and a principal component analysis was carried out using data from 233 mothers of 4.5- to 9-year-old children. The results supported a six-factor model and yielded the following subscales: Responsibility/monitoring; Activity regulation; Control of active behaviours; Overweight concern; Rewarding parenting; and Pressure to exercise. Study 2: Mothers (N = 170) completed the Parenting Related to Activity Measure, alongside measures of eating psychopathology and compulsive exercise, to identify predictors of activity-related parenting practices. Mothers' eating psychopathology and exercise beliefs predicted activity parenting practices with their sons and daughters, but different predictors were seen for mothers of daughters versus sons. Mothers' eating and exercise attitudes are important predictors of their activity-related parenting practices, particularly with girls. Identifying early interactions around activity/exercise could be important in preventing the development of problematic beliefs about exercise, which are often a key symptom of eating disorders. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association.

  5. Testing of porous SiC with dense coating under relevant conditions for Flow Channel Insert application

    Energy Technology Data Exchange (ETDEWEB)

    Ordás, N., E-mail: nordas@ceit.es [CEIT and Tecnun (University of Navarra), Manuel de Lardizábal 15, 20018 San Sebastián (Spain); Bereciartu, A.; García-Rosales, C. [CEIT and Tecnun (University of Navarra), Manuel de Lardizábal 15, 20018 San Sebastián (Spain); Moroño, A.; Malo, M.; Hodgson, E.R. [CIEMAT, Avenida Complutense 22, 28040 Madrid (Spain); Abellà, J.; Colominas, S. [Institut Químic de Sarrià, University Ramon Llull, Via Augusta 390, 08017 Barcelona (Spain); Sedano, L. [CIEMAT, Avenida Complutense 22, 28040 Madrid (Spain)

    2014-10-15

    Highlights: • Porous SiC coated by CVD with a dense coating was developed for Flow Channel Inserts (FCI) in dual-coolant blanket concept. • Porous SiC was obtained following the sacrificial template technique, using Al{sub 2}O{sub 3} and Y{sub 2}O{sub 3} as sintering additives. • Flexural strength, thermal and electrical conductivity, and microstructure of uncoated and coated porous SiC are presented. • Adhesion of coating to porous SiC and its corrosion behavior under Pb-17.5Li at 700 °C are shown. - Abstract: Thermally and electrically insulating porous SiC ceramics are attractive candidates for Flow Channel Inserts (FCI) in dual-coolant blanket concepts thanks to its relatively inexpensive manufacturing route. To prevent tritium permeation and corrosion by Pb-15.7 a dense coating has to be applied on the porous SiC. Despite not having structural function, FCI must exhibit sufficient mechanical strength to withstand strong thermal gradients and thermo-electrical stresses during operation. This work summarizes the results on the development of coated porous SiC for FCI. Porous SiC was obtained following the sacrificial template technique, using Al{sub 2}O{sub 3} and Y{sub 2}O{sub 3} as sintering additives and a carbonaceous phase as pore former. Sintering was performed in inert gas at 1850–1950 °C during 15 min to 3 h, followed by oxidation at 650 °C to eliminate the carbonaceous phase. The most promising bulk materials were coated with a ∼30 μm thick dense SiC by CVD. Results on porosity, bending tests, thermal and electrical conductivity are presented. The microstructure of the coating, its adhesion to the porous SiC and its corrosion behavior under Pb-17.5Li are also shown.

  6. Methodology for the determination of environmental 129I and 99Tc

    International Nuclear Information System (INIS)

    Anderson, T.J.

    1978-01-01

    The Savannah River Laboratory is using existing techniques and developing new methodology to determine the environmental impact of the Savannah River Plant with regard to 129 I and 99 Tc. 129 I is determined by neutron activation after the method of Brauer. Activation products are quantified by γ-ray spectroscopy [Ge(Li)] following chemical isolation. 125 I is used as a yield tracer. 129 I amounts as low as 3.8 fCi can be determined with 30-minute counting times. An isotope dilution method for 99 Tc based on a three-stage surface ionization mass spectrometer is being developed. Its chemical isolation scheme ends with the Tc loaded on a single ion-exchange bead for enhanced mass-spectrometric sensitivity. 97 Tc will be used as a yield tracer. A lower limit of 0.2 fCi is sought. A modified method using liquid scintillation counting has determined 99 Tc in some aqueous samples. These methods have confirmed that 129 I and 99 Tc can be highly mobile in the aqueous environment, establishing the need for monitoring

  7. Relation Between Higher Physical Activity and Public Transit Use

    Science.gov (United States)

    Vernez Moudon, Anne; Kang, Bumjoon; Hurvitz, Philip M.; Zhou, Chuan

    2014-01-01

    Objectives. We isolated physical activity attributable to transit use to examine issues of substitution between types of physical activity and potential confounding of transit-related walking with other walking. Methods. Physical activity and transit use data were collected in 2008 to 2009 from 693 Travel Assessment and Community study participants from King County, Washington, equipped with an accelerometer, a portable Global Positioning System, and a 7-day travel log. Physical activity was classified into transit- and non–transit-related walking and nonwalking time. Analyses compared physical activity by type between transit users and nonusers, between less and more frequent transit users, and between transit and nontransit days for transit users. Results. Transit users had more daily overall physical activity and more total walking than did nontransit users but did not differ on either non–transit-related walking or nonwalking physical activity. Most frequent transit users had more walking time than least frequent transit users. Higher physical activity levels for transit users were observed only on transit days, with 14.6 minutes (12.4 minutes when adjusted for demographics) of daily physical activity directly linked with transit use. Conclusions. Because transit use was directly related to higher physical activity, future research should examine whether substantive increases in transit access and use lead to more physical activity and related health improvements. PMID:24625142

  8. The 1988 CEA progress report on laser research programs

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    The 1988 CEA progress report, concerning laser investigations, is presented. The aim of the research programs on laser/matter interactions is to contribute to the military application works on this field, as well as to the development of the inertial confinement fusion physics. The activities related to the installation and starting of Phebus laser system are described. The development of soft x-ray instrumentation are included. In the field of numerical simulations, the improvement of FCI 1 and 2 codes are extended for increasing the field of the physical phenomena taken into account and getting their use more flexible to the experiment analysis [fr

  9. The Effect of the UO2/ZrO2 Composition on Fuel/Coolant Interaction

    International Nuclear Information System (INIS)

    Song, Jin Ho; Kim, Jong Hwan

    2005-01-01

    A series of experiments on fuel/coolant interaction (FCI) was performed in the TROI facility, where the composition of the mixture was varied. The compositions of the UO 2 and ZrO 2 mixture in weight percent were 50:50, 70:30, 80:20, and pure ZrO 2 . The responses of the system including the temperature of the pool of water in the test vessel, pressure and temperature of the containment vessel, and dynamic pressures and force were measured. In addition, high-speed movies were taken through the windows. The tests using corium with a 70:30 composition and pure zirconia resulted in a spontaneous energetic steam explosion, while the tests with other compositions did not lead to an energetic FCI. The debris size distribution and pressure and temperature responses clearly indicated the cases with an energetic explosion and the cases without an explosion. The high-speed movie taken during the FCI through the visible window clearly disclosed the outstanding phases of the FCI, which were the melt entry phase, the triggering phase, and the continued melt jet and expansion of the mixing zone phase

  10. Correlation of understanding of physics and psychological symptoms among high-school students in Greece

    Science.gov (United States)

    Aggeliki, Anagnostopoulou; Miltiades, Kyprianou; Antigoni-Elisavet, Rota; Evangelia, Pavlatou; Loizos, Zaphiris

    2017-09-01

    Depression may essentially influence cognitive function contributing to poor school performance. The present study undertakes to determine the existence and strength of correlation between depressive symptomatology and other mental conditions with the acquired level of understanding of Newtonian physics taught in schools. The current study recruited 490 students (262 girls, 228 boys) attending the first semester of the Greek Second Grade of General Lyceum School. Force Concept Inventory (FCI) tested the depth of the students’ understanding of Newtonian Physics. Symptom Checklist-90-R assessed general mental status. The tests took place in the classroom during a 1 h session. Low FCI scores significantly correlated with mental conditions, with depression ranking first. Girls had higher scores in all nine symptoms scales of SCL-90 and lower FCI scores. Stepwise regression models proved that the gender effect on FCI could be effectively explained through the significant effect of depression. An understanding of Newtonian physics among high school students may be restricted by common problematic mental conditions, with depression being the greatest among all. Further research, using a more systematic approach to measure depression among adolescents with poor understanding of physics, would help to elucidate the nature of the effect.

  11. FARO test L-14 on fuel coolant interaction and quenching. Comparison report, volume 1 + 2, analysis of the results

    International Nuclear Information System (INIS)

    Annunziato, A.; Addabbo, C.; Yerkess, A.; Silverii, R.; Brewka, W.; Leva, G.

    1997-01-01

    This report provides a comparative analysis of the results from the ISP-39 exercise promoted by OECD-CSNI in the frame of the NEA activities. ISP-39 has been conceived to benchmark the predictive capabilities of computer codes used in the evaluation of fuel-coolant interaction (FCI) and quenching phenomenologies of relevance in water cooled reactors severe accidents safety analysis. The ISP-39 reference case is FARO test L-14, a non-energetic FCI test performed under realistic melt composition and prototypical accident conditions in the FARO experimental installation (Ispra, Italy). Thirteen research organizations from ten countries participated in the exercise submitting 15 prediction calculations with 8 different codes or code versions (COMETA, MC3D, IVA, IFCI, JASMINE, TEXAS, THIRMAL, VAPEX). ISP-39 was conducted as an open exercise. Conclusions are given concerning code capabilities, users effect and sensitivity analyses, numerical accuracy quantification of the predictions, code improvements, general considerations

  12. Body-related self-conscious emotions relate to physical activity motivation and behavior in men.

    Science.gov (United States)

    Castonguay, Andree L; Pila, Eva; Wrosch, Carsten; Sabiston, Catherine M

    2015-05-01

    The aim of this study was to examine the associations between the body-related self-conscious emotions of shame, guilt, and pride and physical activity motivation and behavior among adult males. Specifically, motivation regulations (external, introjected, indentified, intrinsic) were examined as possible mediators between each of the body-related self-conscious emotions and physical activity behavior. A cross-sectional study was conducted with adult men (N = 152; Mage = 23.72, SD = 10.92 years). Participants completed a questionnaire assessing body-related shame, guilt, authentic pride, hubristic pride, motivational regulations, and leisure-time physical activity. In separate multiple mediation models, body-related shame was positively associated with external and introjected regulations and negatively correlated with intrinsic regulation. Guilt was positively linked to external, introjected, and identified regulations. Authentic pride was negatively related to external regulation and positively correlated with both identified and intrinsic regulations and directly associated with physical activity behavior. Hubristic pride was positively associated with intrinsic regulation. Overall, there were both direct and indirect effects via motivation regulations between body-related self-conscious emotions and physical activity (R(2) shame = .15, guilt = .16, authentic pride = .18, hubristic pride = .16). These findings highlight the importance of targeting and understanding self-conscious emotions contextualized to the body and links to motivation and positive health behavior among men. © The Author(s) 2014.

  13. Tides. Ocean Related Curriculum Activities.

    Science.gov (United States)

    Marrett, Andrea

    The ocean affects all of our lives. Therefore, awareness of and information about the interconnections between humans and oceans are prerequisites to making sound decisions for the future. Project ORCA (Ocean Related Curriculum Activities) has developed interdisciplinary curriculum materials designed to meet the needs of students and teachers…

  14. Seal Related Development Activities at EG/G

    Science.gov (United States)

    Greiner, Harold F.

    1991-01-01

    Seal related development activities including modeling, analysis, and performance testing are described for several current seal related projects. Among the current seal related projects are the following: high pressure gas sealing systems for turbomachinery; brush seals for gas path sealing in gas turbines; and tribological material evaluation for wear surfaces in sealing systems.

  15. Social power and approach-related neural activity

    NARCIS (Netherlands)

    M.A.S. Boksem (Maarten); R. Smolders (Ruud); D. de Cremer (David)

    2009-01-01

    textabstractIt has been argued that power activates a general tendency to approach whereas powerlessness activates a tendency to inhibit. The assumption is that elevated power involves reward-rich environments, freedom and, as a consequence, triggers an approach-related motivational orientation and

  16. The determinants of intermediaries’ power over farmers’ margin-related activities

    DEFF Research Database (Denmark)

    Xhoxhi, Orjon; Pedersen, Søren Marcus; Lind, Kim Martin Hjorth

    2014-01-01

    This paper investigates the determinants of intermediaries’ power over farmers’ margin-related activities in Adana, Turkey. In doing so, a holistic model of intermediaries’ power over farmers’ margin-related activities is proposed. The objective of this model is to contribute to a better understa......This paper investigates the determinants of intermediaries’ power over farmers’ margin-related activities in Adana, Turkey. In doing so, a holistic model of intermediaries’ power over farmers’ margin-related activities is proposed. The objective of this model is to contribute to a better...

  17. 29 CFR 780.122 - Activities relating to race horses.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Activities relating to race horses. 780.122 Section 780.122... Activities relating to race horses. Employees engaged in the breeding, raising, and training of horses on..., employees engaged in the racing, training, and care of horses and other activities performed off the farm in...

  18. Applying GPS to enhance understanding of transport-related physical activity.

    Science.gov (United States)

    Duncan, Mitch J; Badland, Hannah M; Mummery, W Kerry

    2009-09-01

    The purpose of the paper is to review the utility of the global positioning system (GPS) in the study of health-related physical activity. The paper draws from existing literature to outline the current work performed using GPS to examine transport-related physical activity, with a focus on the relative utility of the approach when combined with geographic information system (GIS) and other data sources including accelerometers. The paper argues that GPS, especially when used in combination with GIS and accelerometery, offers great promise in objectively measuring and studying the relationship of numerous environmental attributes to human behaviour in terms of physical activity and transport-related activity. Limitations to the use of GPS for the purpose of monitoring health-related physical activity are presented, and recommendations for future avenues of research are discussed.

  19. Psychosocial Variables Related to Why Women are Less Active than Men and Related Health Implications

    Directory of Open Access Journals (Sweden)

    Elizabeth Skidmore Edwards

    2016-01-01

    Full Text Available This article reviews psychosocial influences on women's participation in physical activity as they differ from men and how associated activity differences impact women's risk for a number of chronic diseases. This topic directly aligns with the mission of this special edition related to disparities in women's health as the typically lower level of physical activity in females directly impacts their health. On average, females participate in physical activity at lower rates than their male counterparts. These lower rates of physical activity are directly related to both incidence of and outcomes from cardiovascular disease, type 2 diabetes, and breast and gynecological cancers. The relationship between psychosocial factors that are understood to affect physical activity differs between men and women. Specifically, self-efficacy, social support, and motivation are empirically substantiated factors that found to impact physical activity participation among women differently than men. Understanding these relationships is integral to designing effective interventions to target physical activity participation in women so that the related health risks are adequately addressed.

  20. Study of Relation between Physical Activity and Preterm Birth

    Directory of Open Access Journals (Sweden)

    Mehran N.

    2012-04-01

    Full Text Available Background and Objectives: Preterm birth is the main cause of neonatal mortality and morbidity and the importance of knowing its causes is clear. Since the effect of physical activity on preterm birth is unknown and its prevention is the priority in health care, we decided to do this study with the aim of determining the relation between physical activity and preterm birth. Methods: In this case-control study, 300 pregnant women delivering in Izadi Hospital in Qom, Iran in the second half of 2008, selected through simple sampling. The data were collected using standard pregnancy physical activity questionnaire that categorizes the physical activity into 4 groups: work activities, home activities, transport activities and fun/exercise activities. The physical activity severity was calculated as MET (Metabolic Equivalence Test. Finally, the data were analyzed using descriptive and analytic (x2 and t test statistics. A p<0.05 was considered as significant.Results: The findings didn't show any significant relation between physical activity and preterm birth. In addition, in view of activity type, fun/exercise and work activities (respectively and in view of activity severity, sedentary and moderate activities (respectively were associated with higher, but insignificant rate of preterm birth. Among demographic factors, only gravidity of women was significantly associated with preterm birth.Conclusion: Although, in this study the significant relation between physical activity and preterm delivery wasn't observed, the same research with further sample is recommended.

  1. Transit use and physical activity: Findings from the Houston travel-related activity in neighborhoods (TRAIN study

    Directory of Open Access Journals (Sweden)

    Gregory Knell

    2018-03-01

    Full Text Available Transportation-related physical activity can significantly increase daily total physical activity through active transportation or walking/biking to transit stops. The purpose of this study was to assess the relations between transit-use and self-reported and monitor-based physical activity levels in a predominantly minority population from the Houston Travel-Related Activity in Neighborhoods (TRAIN Study. This was a cross-sectional analysis of 865 adults living in Houston, Texas between 2013 and 2015. The exposure variable was transit-use (non-users, occasional users, and primary users. Self-reported and accelerometer-determined physical activity were the outcomes of interest. Regression models adjusting for age, sex, race/ethnicity, and other covariates of interest were built to test the hypothesis that transit user status was directly associated with 1 minutes of moderate-intensity physical activity and 2 the prevalence of achieving the physical activity guidelines. The majority of participants were female, non-Hispanic black, and almost one-third had a high school education or less. After adjustment, primary transit-use was associated with 134.2 (p<0.01 additional mean minutes per week of self-reported moderate-intensity transportation-related physical activity compared to non-users. Further, primary users had 7.3 (95% CI: 2.6–20.1 times the relative adjusted odds of meeting physical activity recommendations than non-users based on self-reported transportation-related physical activity. There were no statistically significant associations of transit-use with self-reported leisure-time or accelerometer-derived physical activity. Transit-use has the potential for a large public health impact due to its sustainability and scalability. Therefore, encouraging the use of transit as a means to promote physical activity should be examined in future studies. Keywords: Physical activity, Transportation, Commuting, Motor activity, Urban health

  2. Quality Control Activities Related to Mechanical Maintenance of Safety Related Components at Krsko NPP

    International Nuclear Information System (INIS)

    Djakovic, D.

    2016-01-01

    For successful, safe and reliable operation of nuclear power plant, maintenance processes have to be systematically controlled and procedures for quality control of maintenance activities shall be established. This is requested by the quality assurance program, which shall provide control over activities affecting the quality of structures, systems, and components, considering their importance to safety. As a part of Quality and Nuclear Oversight Division (QNOD; SKV), the Quality Control Department (QC) provides quality control activities, which are deeply involved in maintenance processes at Krsko NPP, both on safety related and non-safety related (non-nuclear safety) components. QC activities on safety related components have to fulfil all requirements, which will enable the components to perform their intended safety functions. This paper describes quality control activities related to mechanical maintenance of safety related components at Krsko NPP and significant role of the Krsko plant QC Department in three particular maintenance cases connected with safety related components. In these three specific cases, the QC has confirmed its importance in compliance with quality assurance program and presented its significant added value in providing safe and reliable operation of the plant. The first maintenance activity was installation of nozzle check valves in the scope of a modification for improving regulation of spent fuel pit pumps. The QC Department performed receipt inspection of the valves. Using non-destructive examination methods and X-ray spectrometry, it was found out that the valve diffuser was made of improper material, which could cause progressive corrosion of the valve diffuser in borated water and consequently a loss of safety function of the valves followed by long-term consequences. The second one was the receipt inspection of containment ventilation fan coolers. The coolers were claimed and sent back to the supplier because the QC Department

  3. Transit use and physical activity: Findings from the Houston travel-related activity in neighborhoods (TRAIN) study.

    Science.gov (United States)

    Knell, Gregory; Durand, Casey P; Shuval, Kerem; Kohl Iii, Harold W; Salvo, Deborah; Sener, Ipek; Gabriel, Kelley Pettee

    2018-03-01

    Transportation-related physical activity can significantly increase daily total physical activity through active transportation or walking/biking to transit stops. The purpose of this study was to assess the relations between transit-use and self-reported and monitor-based physical activity levels in a predominantly minority population from the Houston Travel-Related Activity in Neighborhoods (TRAIN) Study. This was a cross-sectional analysis of 865 adults living in Houston, Texas between 2013 and 2015. The exposure variable was transit-use (non-users, occasional users, and primary users). Self-reported and accelerometer-determined physical activity were the outcomes of interest. Regression models adjusting for age, sex, race/ethnicity, and other covariates of interest were built to test the hypothesis that transit user status was directly associated with 1) minutes of moderate-intensity physical activity and 2) the prevalence of achieving the physical activity guidelines. The majority of participants were female, non-Hispanic black, and almost one-third had a high school education or less. After adjustment, primary transit-use was associated with 134.2 ( p  < 0.01) additional mean minutes per week of self-reported moderate-intensity transportation-related physical activity compared to non-users. Further, primary users had 7.3 (95% CI: 2.6-20.1) times the relative adjusted odds of meeting physical activity recommendations than non-users based on self-reported transportation-related physical activity. There were no statistically significant associations of transit-use with self-reported leisure-time or accelerometer-derived physical activity. Transit-use has the potential for a large public health impact due to its sustainability and scalability. Therefore, encouraging the use of transit as a means to promote physical activity should be examined in future studies.

  4. Some aspects of public relation activities at Russian NPPs

    International Nuclear Information System (INIS)

    Ermakov, Sergei

    1995-01-01

    Full text: Since 1992 Rosenergoatom has managed most of the Russian NPPs. Here in this report we present its main public relations activities. 1. The leading role of the management of Rosenergoatom (Direction of Public Relations) is in relations with the public. 2. The main public relations activities are: - contact with the selected and administrative authorities of different levels, - interaction with mass media, - information of employees, - information of, and interaction with, the people of the areas close to the NPPs and especially of the nearby towns, - organising and carrying out opinion polls, - celebration campaigns at NPPs. 3. The use of NPPs' information centers and groups for PR activities: - construction and equipping of NPPs' public information centers; organising excursions, lectures, debates at NPPs; - publishing of news papers at NPPs and at NPPs' towns. 4. Public information in the regions close to the NPPs construction sites (Far East, Kostroma, Rostov, Veronezh regions). 5. Conclusions on the activities and plans for the future. (author)

  5. Water chemistry-related activities at the IAEA

    International Nuclear Information System (INIS)

    Cheng, H.; Onufriev, V.

    2005-01-01

    Water chemistry activities and publications in the past are listed. IAEA Coordinated Research Programmes, WWER-1000 SG water chemistry database, materials issues TM in Vienna, TC workshops and attendance of international meetings, publications. There is a list of IAEA publications related to water chemistry and corrosion. Finally water chemistry activities planned for 2006-2008 are detailed. (N.T.)

  6. Introduction to the modified TROI test facility for fuel coolant interaction under a submerged reactor vessel

    International Nuclear Information System (INIS)

    Na, Young Su; Hong, Seong-Wan; Song, Jin Ho; Hong, Seong-Ho

    2014-01-01

    The molten Fuel-Coolant Interaction (FCI) can threaten the integrity of the reactor cavity under a severe accident. A steam explosion can be occurred by the rapid energy transfer in the high-temperature corium melt jet penetrating into water, which makes the dynamic load applying to the surrounding structure. Before a steam explosion, the corium melt jet breaks into small-sized particles, and the steam is generated continuously by the film boiling on the hot surface of the melt contacting with water. The premixing phase consisting of the corium melt, water, and steam can determine the intensity of the steam explosion. Unfortunately, the previous experimental studies on the FCI phenomena have carried out under a free fall of the corium melt jet in a gas phase before interacting with water. The previous TROI (Test for Real cOrium Interaction with water) test facility, that is a well-known test facility for the FCI phenomena in the world, has observed a steam explosion under a free fall of a corium melt jet in a gas phase before contacting a coolant since 2000, which is changing to simulate the FCI phenomena under a submerged reactor vessel. This study introduces the modified TROI test facility as shown in Fig. 1 and the considerations for the experiment with success. The previous TROI test facility, that has observed the molten Fuel-Coolant Interaction (FCI) with a free fall of the prototypic corium melt in a gas phase before contacting a coolant, was modified to simulate the FCI phenomena under a submerged reactor vessel for the assessment of the In-Vessel Retention (IVR) concept, i.e., without a free-fall distance of the corium melt before contacting water. The superheated prototypic corium melt created by the cold crucible melting method moves on a releasing valve newly installed just above the water level in the interaction vessel. The corium melt will stay on a releasing valve in less than 0.2 seconds to reduce heat loss for preventing the solidification, and

  7. Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY.

    Science.gov (United States)

    Carli, E; Carminato, A; Ravagnan, S; Capello, K; Antognoni, M T; Miglio, A; Furlanello, T; Proverbio, D; Spada, E; Stefani, A; Mutinelli, F; Vascellari, M

    2017-11-29

    The prevalence of dog erythrocyte antigen (DEA 1) in canine population is approximately 40-60%. Often data are limited to a small number of breeds and/or dogs. The aims of this study were to evaluate frequency of DEA 1 in a large population of purebred and mongrel dogs including Italian native breeds and to recognize a possible association between DEA 1 and breed, sex, and genetic and phenotypical/functional classifications of breeds. Frequencies of DEA 1 blood group collected from screened/enrolled blood donors and from healthy and sick dogs were retrospectively evaluated. The breed and the sex were recorded when available. DEA 1 blood typing was assessed by immunocromatographic test on K3EDTA blood samples. The prevalence of DEA 1 antigen was statistically related to breed, gender, Fédération Cynologique Internationale (FCI) and genotypic grouping. Sixty-two per cent dogs resulted DEA 1+ and 38% DEA 1-. DEA 1- was statistically associated with Dogo Argentino, Dobermann, German Shepherd, Boxer, Corso dogs, the molossian dogs, the FCI group 1, 2 and 3 and the genetic groups "working dogs" and "mastiff". DEA 1+ was statistically associated with Rottweiler, Briquet Griffon Vendéen, Bernese mountain dog, Golden Retriever, the hunting breeds, the FCI group 4, 6, 7 and 8 and the genetic groups "scent hounds" and "retrievers". No gender association was observed. Data obtained by this work may be clinically useful to drive blood donor enrollment and selection among different breeds.

  8. 12 CFR 225.123 - Activities closely related to banking.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Activities closely related to banking. 225.123 Section 225.123 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL... Holding Companies Interpretations § 225.123 Activities closely related to banking. (a) Effective June 15...

  9. Active Metric Learning from Relative Comparisons

    OpenAIRE

    Xiong, Sicheng; Rosales, Rómer; Pei, Yuanli; Fern, Xiaoli Z.

    2014-01-01

    This work focuses on active learning of distance metrics from relative comparison information. A relative comparison specifies, for a data point triplet $(x_i,x_j,x_k)$, that instance $x_i$ is more similar to $x_j$ than to $x_k$. Such constraints, when available, have been shown to be useful toward defining appropriate distance metrics. In real-world applications, acquiring constraints often require considerable human effort. This motivates us to study how to select and query the most useful ...

  10. Age-related patterns of vigorous-intensity physical activity in youth

    DEFF Research Database (Denmark)

    Corder, Kirsten; Sharp, Stephen J; Atkin, Andrew J

    2016-01-01

    the relative reduction was 6.0% (5.6%, 6.4%). The age-related decrease in vigorous-intensity activity remained after adjustment for moderate activity. A larger age-related decrease in vigorous activity was observed for girls (- 10.7%) versus boys (- 2.9%), non-white (- 12.9% to - 9.4%) versus white individuals......Physical activity declines during youth but most evidence reports on combined moderate and vigorous-intensity physical activity. We investigated how vigorous-intensity activity varies with age. Cross-sectional data from 24,025 participants (5.0-18.0 y; from 20 studies in 10 countries obtained 2008...... (- 6.1%), lowest maternal education (high school (- 2.0%)) versus college/university (ns) and for overweight/obese (- 6.1%) versus healthy-weight participants (- 8.1%). In addition to larger annual decreases in vigorous-intensity activity, overweight/obese individuals, girls and North Americans had...

  11. Activity Engagement and Activity-Related Experiences: The Role of Personality.

    Science.gov (United States)

    Newton, Nicky J; Pladevall-Guyer, Jana; Gonzalez, Richard; Smith, Jacqui

    2016-08-12

    The associations of personality with activity participation and well-being have been well studied. However, less is known concerning the relationship between personality and specific aspects of activity engagement in older adults. We conducted a fine-grained examination of the effects of extraversion and conscientiousness on reported activity engagement-which we define as participation, time allocated, and affective experience-during 8 everyday activities. Data were obtained using a day reconstruction measure from a subgroup of participants in the 2012 Health and Retirement Study (HRS: N = 5,484; mean age = 67.98 years). We found mixed support for hypotheses suggesting that specific personality traits would be associated with activity participation, time allocated, and activity-affective experience. For example, extraverts were more likely to socialize and experienced higher socializing-related positive affect, but did not spend more time socializing. Results are discussed in light of the value of including personality in, and its contribution to, studies of activity engagement in later life. In addition, the need to acknowledge the complexity of the concept of activity engagement in future research is highlighted. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Visual short term memory related brain activity predicts mathematical abilities.

    Science.gov (United States)

    Boulet-Craig, Aubrée; Robaey, Philippe; Lacourse, Karine; Jerbi, Karim; Oswald, Victor; Krajinovic, Maja; Laverdière, Caroline; Sinnett, Daniel; Jolicoeur, Pierre; Lippé, Sarah

    2017-07-01

    Previous research suggests visual short-term memory (VSTM) capacity and mathematical abilities are significantly related. Moreover, both processes activate similar brain regions within the parietal cortex, in particular, the intraparietal sulcus; however, it is still unclear whether the neuronal underpinnings of VSTM directly correlate with mathematical operation and reasoning abilities. The main objective was to investigate the association between parieto-occipital brain activity during the retention period of a VSTM task and performance in mathematics. The authors measured mathematical abilities and VSTM capacity as well as brain activity during memory maintenance using magnetoencephalography (MEG) in 19 healthy adult participants. Event-related magnetic fields (ERFs) were computed on the MEG data. Linear regressions were used to estimate the strength of the relation between VSTM related brain activity and mathematical abilities. The amplitude of parieto-occipital cerebral activity during the retention of visual information was related to performance in 2 standardized mathematical tasks: mathematical reasoning and calculation fluency. The findings show that brain activity during retention period of a VSTM task is associated with mathematical abilities. Contributions of VSTM processes to numerical cognition should be considered in cognitive interventions. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Isometric arm strength and subjective rating of upper limb fatigue in two-handed carrying tasks.

    Science.gov (United States)

    Li, Kai Way; Chiu, Wen-Sheng

    2015-01-01

    Sustained carrying could result in muscular fatigue of the upper limb. Ten male and ten female subjects were recruited for measurements of isometric arm strength before and during carrying a load for a period of 4 minutes. Two levels of load of carrying were tested for each of the male and female subjects. Exponential function based predictive equations for the isometric arm strength were established. The mean absolute deviations of these models in predicting the isometric arm strength were in the range of 3.24 to 17.34 N. Regression analyses between the subjective ratings of upper limb fatigue and force change index (FCI) for the carrying were also performed. The results indicated that the subjective rating of muscular fatigue may be estimated by multiplying the FCI with a constant. The FCI may, therefore, be adopted as an index to assess muscular fatigue for two-handed carrying tasks.

  14. Analysis of 210Pb and 210Po concentrations in surface air by an α spectrometric method

    International Nuclear Information System (INIS)

    Winkler, R.; Hoetzl, H.; Chatterjee, B.

    1981-01-01

    A method is presented for determining the concentrations of airborne 210 Pb and 210 Po. The method employs α spectrometry to measure the count rate of 210 Po present on an electrostatic filter sample at two post-sampling times. The individual air concentrations of 210 Po and 210 Pb can be calculated from equations given. Sensitivity of the procedure is about 0.2 fCi 210 Po per m 3 of air. The method was applied to the study of long-term variations and frequency distributions of 210 Po and 210 Pb concentrations in surface air at a nonpolluted location about 10 km outside of Munich, F.R.G., from 1976 through 1979. During this period the average concentration levels were found to be 14.2 fCi 210 Pb per m 3 of air and 0.77 fCi 210 Po per m 3 of air, respectively. (author)

  15. 29 CFR 779.207 - Related activities in retail operations.

    Science.gov (United States)

    2010-07-01

    ... ACT AS APPLIED TO RETAILERS OF GOODS OR SERVICES Employment to Which the Act May Apply; Enterprise... store are “related activities,” even if the store sells a great variety of different types of goods and... of goods or services, of any type, are related activities and they will be considered one enterprise...

  16. Assessment of relative active tectonics, south central Alborz (north Iran)

    Science.gov (United States)

    Khavari, R.; Ghorashi, M.; Arian, M.

    2009-04-01

    The paper present a method for evaluating relative active tectonics based on geomorphic indices useful in evaluating morphology and topography. Indices used include: stream length-gradient index (SL), drainage basin asymmetry (Af), hypsometric integral (Hi), ratio of valley-floor width to valley height (Vf), index of drainage basin shape (Bs), and index of mountain front sinuosity (Smf). Results from the analysis are accumulated and expressed as an index of relative active tectonics (Iat), which we divide into four classes from relatively low to highest tectonic activity. The study area along the south flank of the central Alborz mountain range in north Iran is an ideal location to test the concept of an index to predict relative tectonic activity on a basis of area rather than a single valley or mountain front. The recent investigations show that neotectonism has played a key role in the geomorphic evolution of this part of the Alborz mountain range. Geomorphic indices indicate the presence of differential uplifting in the geological past. The area surrounding the Amirkabir lake shows very high relative tectonic activity.

  17. Biochemical activity of fullerenes and related derivatives

    International Nuclear Information System (INIS)

    Huczko, A.; Lange, H.; Calko, E.

    1999-01-01

    An astonishing scientific interest, embodied in over 15000 research articles so far, has been encountered since 1985 when fullerenes were discovered. From new superconductors to a rich electrochemistry and reaction chemistry, fullerene nanostructures continue to excite the scientific world, and new findings continue at record pace. This review presents many examples of the biochemical activities of fullerenes and derivatives, e. g. cytotoxic activity, selective DNA cleavage and antiviral activity against HIV. We also present some results of our testing which show that, despite its chemical and biochemical activity, fullerene matter does not present any health hazard directly related to skin irritation and allergic risks. (author)

  18. Cross-language activation of morphological relatives in cognates: the role of orthographic overlap and task-related processing

    NARCIS (Netherlands)

    Mulder, K.; Dijkstra, A.F.J.; Baayen, R.H.

    2015-01-01

    We considered the role of orthography and task-related processing mechanisms in the activation of morphologically related complex words during bilingual word processing. So far, it has only been shown that such morphologically related words (i.e., morphological family members) are activated through

  19. Stroke survivors' and relatives' negotiation of relational and activity changes: A qualitative study.

    Science.gov (United States)

    Arntzen, Cathrine; Hamran, Torunn

    2016-01-01

    This study explores stroke survivors' and relatives' negotiation of relational and activity change in their interrelated long-term meaning-making processes of everyday life and what it means for the experience of progress and well-being. Repeated retrospective in-depth interviews were conducted with both the stroke survivor and relatives. A Critical Psychological Perspective gives the frame of reference to study more closely what is going on in and across particular contexts in family members' ongoing social practices. An asymmetric problematic relationship can develop among the participants in the context of family life. However, the analysis identifies six beneficial relational and activity changes, which contribute to a reciprocal, balanced repositioning, and help the family move in a more positive direction. The repositioning processes facilitate a new transformation of family we-ness, which is important for the participants' experience of process and well-being. The comprehensive family work that has to be done is about managing the imbalance of everyday life, upholding separate activities outside the family sphere and dealing with the fact that peripheral others become more peripheral. The study addresses some arguments for taking a family-centred perspective in occupational therapy practice, as well as in a stroke rehabilitation service in general.

  20. A reassessment of the potential for an alpha-mode containment failure and a review of the current understanding of broader fuel-coolant interaction issues. Second steam explosion review group workshop

    Energy Technology Data Exchange (ETDEWEB)

    Basu, S. [Nuclear Regulatory Commission, Washington, DC (United States); Ginsberg, T. [Brookhaven National Lab., Upton, NY (United States)

    1996-08-01

    This report summarizes the review and evaluation by experts of the current understanding of the molten fuel-coolant interaction (FCI) issues covering the complete spectrum of interactions, i.e., from mild quenching to very energetic interactions including those that could lead to the alpha-mode containment failure. Of the eleven experts polled, all but two concluded that the alpha-mode failure issue was resolved from a risk perspective, meaning that this mode of failure is of very low probability, that it is of little or no significance to the overall risk from a nuclear power plant, and that any further reduction in residual uncertainties is not likely to change the probability in an appreciable manner. To a lesser degree, discussions also took place on the broader FCI issues such as mild quenching of core melt during non-explosive FCI, and shock loading of lower head and ex-vessel support structures arising from explosive localized FCIs. These latter issues are relevant with regard to determining the efficacy of certain accident management strategies for operating reactors as well as for advanced light water reactors. The experts reviewed the status of understanding of the FCI phenomena in the context of these broader issues, identified residual uncertainties in the understanding, and recommended future research (both experimental and analytical) to reduce the uncertainties.

  1. A reassessment of the potential for an alpha-mode containment failure and a review of the current understanding of broader fuel-coolant interaction issues. Second steam explosion review group workshop

    International Nuclear Information System (INIS)

    Basu, S.; Ginsberg, T.

    1996-08-01

    This report summarizes the review and evaluation by experts of the current understanding of the molten fuel-coolant interaction (FCI) issues covering the complete spectrum of interactions, i.e., from mild quenching to very energetic interactions including those that could lead to the alpha-mode containment failure. Of the eleven experts polled, all but two concluded that the alpha-mode failure issue was resolved from a risk perspective, meaning that this mode of failure is of very low probability, that it is of little or no significance to the overall risk from a nuclear power plant, and that any further reduction in residual uncertainties is not likely to change the probability in an appreciable manner. To a lesser degree, discussions also took place on the broader FCI issues such as mild quenching of core melt during non-explosive FCI, and shock loading of lower head and ex-vessel support structures arising from explosive localized FCIs. These latter issues are relevant with regard to determining the efficacy of certain accident management strategies for operating reactors as well as for advanced light water reactors. The experts reviewed the status of understanding of the FCI phenomena in the context of these broader issues, identified residual uncertainties in the understanding, and recommended future research (both experimental and analytical) to reduce the uncertainties

  2. Age-related increase in brain activity during task-related and -negative networks and numerical inductive reasoning.

    Science.gov (United States)

    Sun, Li; Liang, Peipeng; Jia, Xiuqin; Qi, Zhigang; Li, Kuncheng

    2014-01-01

    Recent neuroimaging studies have shown that elderly adults exhibit increased and decreased activation on various cognitive tasks, yet little is known about age-related changes in inductive reasoning. To investigate the neural basis for the aging effect on inductive reasoning, 15 young and 15 elderly subjects performed numerical inductive reasoning while in a magnetic resonance (MR) scanner. Functional magnetic resonance imaging (fMRI) analysis revealed that numerical inductive reasoning, relative to rest, yielded multiple frontal, temporal, parietal, and some subcortical area activations for both age groups. In addition, the younger participants showed significant regions of task-induced deactivation, while no deactivation occurred in the elderly adults. Direct group comparisons showed that elderly adults exhibited greater activity in regions of task-related activation and areas showing task-induced deactivation (TID) in the younger group. Our findings suggest an age-related deficiency in neural function and resource allocation during inductive reasoning.

  3. Trade-offs between commuting time and health-related activities.

    Science.gov (United States)

    Christian, Thomas J

    2012-10-01

    To further understand documented associations between obesity and urban sprawl, this research describes individuals' trade-offs between health-related activities and commuting time. A cross-section of 24,861 working-age individuals employed full-time and residing in urban counties is constructed from the American Time Use Survey (2003-2010). Data are analyzed using seemingly unrelated regressions to quantify health-related activity decreases in response to additional time spent commuting. Outcomes are total daily minutes spent in physical activity at a moderate or greater intensity, preparing food, eating meals with family, and sleeping. Commuting time is measured as all travel time between home and work and vice versa. The mean commuting time is 62 min daily, the median is 55 min, and 10.1% of workers commute 120 min or more. Spending an additional 60 min daily commuting above average is associated with a 6% decrease in aggregate health-related activities and spending an additional 120 min is associated with a 12% decrease. The greatest percentage of commuting time comes from sleeping time reductions (28-35%). Additionally, larger proportions of commuting time are taken from physical activity and food preparation relative to the mean commuting length: of 60 min spent commuting, 16.1% is taken from physical activity and 4.1% is taken from food preparation; of 120 min commuting, 20.3% is taken from physical activity and 5.6% is taken from food preparation. The results indicate that longer commutes are associated with behavioral patterns which over time may contribute to obesity and other poor health outcomes. These findings will assist both urban planners and researchers wishing to understand time constraints' impacts on health.

  4. Jealousy increased by induced relative left frontal cortical activity.

    Science.gov (United States)

    Kelley, Nicholas J; Eastwick, Paul W; Harmon-Jones, Eddie; Schmeichel, Brandon J

    2015-10-01

    Asymmetric frontal cortical activity may be one key to the process linking social exclusion to jealous feelings. The current research examined the causal role of asymmetric frontal brain activity in modulating jealousy in response to social exclusion. Transcranial direct-current stimulation (tDCS) over the frontal cortex to manipulate asymmetric frontal cortical activity was combined with a modified version of the Cyberball paradigm designed to induce jealousy. After receiving 15 min of tDCS, participants were excluded by a desired partner and reported how jealous they felt. Among individuals who were excluded, tDCS to increase relative left frontal cortical activity caused greater levels of self-reported jealousy compared to tDCS to increase relative right frontal cortical activity or sham stimulation. Limitations concerning the specificity of this effect and implications for the role of the asymmetric prefrontal cortical activity in motivated behaviors are discussed. (c) 2015 APA, all rights reserved).

  5. Quantum computing applied to calculations of molecular energies: CH2 benchmark.

    Science.gov (United States)

    Veis, Libor; Pittner, Jiří

    2010-11-21

    Quantum computers are appealing for their ability to solve some tasks much faster than their classical counterparts. It was shown in [Aspuru-Guzik et al., Science 309, 1704 (2005)] that they, if available, would be able to perform the full configuration interaction (FCI) energy calculations with a polynomial scaling. This is in contrast to conventional computers where FCI scales exponentially. We have developed a code for simulation of quantum computers and implemented our version of the quantum FCI algorithm. We provide a detailed description of this algorithm and the results of the assessment of its performance on the four lowest lying electronic states of CH(2) molecule. This molecule was chosen as a benchmark, since its two lowest lying (1)A(1) states exhibit a multireference character at the equilibrium geometry. It has been shown that with a suitably chosen initial state of the quantum register, one is able to achieve the probability amplification regime of the iterative phase estimation algorithm even in this case.

  6. Distribution of caesium-137 in the Mediterranean Sea

    International Nuclear Information System (INIS)

    Fukai, R.; Ballestra, S.; Vas, D.

    1980-01-01

    The International Laboratory of Marine Radioactivity (Monaco) conducted several oceanographic cruises during 1975-1977 to collect data on heavy metals and chlorinated hydrocarbons in the open Mediterranean. Sea water samples for radionuclide measurements were also collected on these cruises. The 137 Cs measurements in these samples are presented and discussed. After collection sea water was immediately acidified to pH 1.5 and 137 Cs was sorbed on solid ammonium phosphomolybdate together with added stable cesium carrier. After dissolution of AMP by NaoH, Cs was separated from K and Rb by ion exchange, precipitated as chloroplatinate and beta-counted. The surface concentrations of 137 Cs in the different areas of the Mediterranean fall in the range of 80-180 fCi 137 Cs/l, the average of all values being 126 +- 7 fCi 137 Cs. The vertical distribution of 137 Cs measured at four different locations varied considerably. It increased from surface to a maximum at a depth between 50m and 250m and then decreased with depth. The depth of maximum concentration differed from station to station but was always above the chlorinity maximum. The vertical distribution, therefore, seems to be closely related to vertical water mass movements. The inventories of 137 Cs delivered by radioactive fallout into the Mediterranean water columns are computed on the basis 137 Cs/ 90 Sr activity ratio and presented. (M.G.B.)

  7. Recovery of active pathogenesis-related enzymes from the apoplast ...

    African Journals Online (AJOL)

    Overall protease activity intensity was higher in the symplast. Maximum symplast contamination of the apoplast was 2% as estimated by glucose 6-phosphate dehydrogenase activity, a biochemical marker for symplast. Accumulation of pathogenesis-related enzymatic activities in the apoplast of M. acuminata leaf tissue was ...

  8. Description and performance of the OGSE for VNIR absolute spectroradiometric calibration of MTG-I satellites

    Science.gov (United States)

    Glastre, W.; Marque, J.; Compain, E.; Deep, A.; Durand, Y.; Aminou, D. M. A.

    2017-09-01

    The Meteosat Third Generation (MTG) Programme is being realised through the well-established and successful Cooperation between EUMETSAT and ESA. It will ensure the future continuity of MSG with the capabilities to enhance nowcasting, global and regional numerical weather prediction, climate and atmospheric chemistry monitoring data from Geostationary Orbit. This will be achieved through a series of 6 satellites named MTG-I and MTG-S to bring to the meteorological community continuous high spatial, spectral and temporal resolution observations and geophysical parameters of the Earth based on sensors from the geo-stationary orbit. In particular, the imagery mission MTG-I will bring an improved continuation of the MSG satellites series with the Flexible Combined Imager (FCI) a broad spectral range (from UV to LWIR) with better spatial and spectral resolutions. The FCI will be able to take high spatial resolution pictures of the Earth within 8 VNIR and 8 IR channels. As one of the mission of this instrument is to provide a quantitative analysis of atmosphere compounds, the absolute observed radiance needs to be known with a specified accuracy for VNIR as low as to 5% at k=3 over its full dynamic. While the FCI is regularly recalibrated every 6 month at equinoxes, it is however requiring initial ground calibration for the beginning of its mission. The Multi Optical Test Assembly (MOTA) is one of the Optical Ground Support Equipment (OGSE) dedicated to various missions necessary for the integration of the FCI . This equipment, provided by Bertin Technologies, will be delivered to TAS-F by the end of 2016. One of its mission, is the on-ground absolute calibration of VNIR channels. In order to handle this, the MOTA will be placed in front of the FCI under representative vacuum conditions and will be able to project a perfectly known, calibrated radiance level within the full dynamic of FCI instrument. The main difficulty is the very demanding calibration level with

  9. Food-Related Odors Activate Dopaminergic Brain Areas

    OpenAIRE

    Agnieszka Sorokowska; Agnieszka Sorokowska; Katherina Schoen; Cornelia Hummel; Pengfei Han; Jonathan Warr; Thomas Hummel

    2017-01-01

    Food-associated cues of different sensory categories have often been shown to be a potent elicitor of cerebral activity in brain reward circuits. Smells influence and modify the hedonic qualities of eating experience, and in contrast to smells not associated with food, perception of food-associated odors may activate dopaminergic brain areas. In this study, we aimed to verify previous findings related to the rewarding value of food-associated odors by means of an fMRI design involving careful...

  10. Extraction of Children's Friendship Relation from Activity Level

    Science.gov (United States)

    Kono, Aki; Shintani, Kimio; Katsuki, Takuya; Kihara, Shin'ya; Ueda, Mari; Kaneda, Shigeo; Haga, Hirohide

    Children learn to fit into society through living in a group, and it's greatly influenced by their friend relations. Although preschool teachers need to observe them to assist in the growth of children's social progress and support the development each child's personality, only experienced teachers can watch over children while providing high-quality guidance. To resolve the problem, this paper proposes a mathematical and objective method that assists teachers with observation. It uses numerical data of activity level recorded by pedometers, and we make tree diagram called dendrogram based on hierarchical clustering with recorded activity level. Also, we calculate children's ``breadth'' and ``depth'' of friend relations by using more than one dendrogram. When we record children's activity level in a certain kindergarten for two months and evaluated the proposed method, the results usually coincide with remarks of teachers about the children.

  11. Multiple active forms of thrombin. IV. Relative activities of meizothrombins

    Energy Technology Data Exchange (ETDEWEB)

    Doyle, M.F.; Mann, K.G. (Univ. of Vermont College of Medicine, Burlington (USA))

    1990-06-25

    The prothrombin activation intermediates meizothrombin and meizothrombin(desF1) (meizothrombin that has been autoproteolyzed to remove fragment 1) have been obtained in a relatively pure, active form with minimal autolysis, making them suitable for enzymatic characterization. When compared at equimolar concentrations, alpha-thrombin, fragment 1.2+ alpha-thrombin, meizothrombin(desF1), and meizothrombin have approximately 100, 100, 10, and 1% activity, respectively, toward the macromolecular substrates factor V, fibrinogen, and platelets. The difference in activity of these four enzymes cannot be attributed to alterations in the catalytic triad, as all four enzymes have nearly identical catalytic efficiency toward the chromogenic substrate S2238. Further, the ability of meizothrombin and meizothrombin(desF1) to activate protein C was 75% of the activity exhibited by alpha-thrombin or fragment 1.2+ alpha-thrombin. All four enzymes bind to thrombomodulin, as judged by the enhanced rate of protein C activation upon preincubation of the enzymes with thrombomodulin. The extent of rate enhancement varied, with meizothrombin/thrombomodulin exhibiting only 50% of the alpha-thrombin/thrombomodulin rate. This difference in rate is not due to a decreased affinity of the meizothrombin for thrombomodulin since the apparent dissociation constants for the alpha-thrombin-thrombomodulin complex and the meizothrombin-thrombomodulin complex are virtually identical. The difference in the observed rate is due in part to the higher Km for protein C exhibited by the meizothrombin-thrombomodulin complex. Incubation of the thrombomodulin-enzyme complex with phospholipid vesicles caused an increase in the protein C activation rates. The kinetic constants for protein C activation in the presence of phospholipid are virtually identical for these enzyme-thrombomodulin complexes.

  12. Multiple active forms of thrombin. IV. Relative activities of meizothrombins

    International Nuclear Information System (INIS)

    Doyle, M.F.; Mann, K.G.

    1990-01-01

    The prothrombin activation intermediates meizothrombin and meizothrombin(desF1) (meizothrombin that has been autoproteolyzed to remove fragment 1) have been obtained in a relatively pure, active form with minimal autolysis, making them suitable for enzymatic characterization. When compared at equimolar concentrations, alpha-thrombin, fragment 1.2+ alpha-thrombin, meizothrombin(desF1), and meizothrombin have approximately 100, 100, 10, and 1% activity, respectively, toward the macromolecular substrates factor V, fibrinogen, and platelets. The difference in activity of these four enzymes cannot be attributed to alterations in the catalytic triad, as all four enzymes have nearly identical catalytic efficiency toward the chromogenic substrate S2238. Further, the ability of meizothrombin and meizothrombin(desF1) to activate protein C was 75% of the activity exhibited by alpha-thrombin or fragment 1.2+ alpha-thrombin. All four enzymes bind to thrombomodulin, as judged by the enhanced rate of protein C activation upon preincubation of the enzymes with thrombomodulin. The extent of rate enhancement varied, with meizothrombin/thrombomodulin exhibiting only 50% of the alpha-thrombin/thrombomodulin rate. This difference in rate is not due to a decreased affinity of the meizothrombin for thrombomodulin since the apparent dissociation constants for the alpha-thrombin-thrombomodulin complex and the meizothrombin-thrombomodulin complex are virtually identical. The difference in the observed rate is due in part to the higher Km for protein C exhibited by the meizothrombin-thrombomodulin complex. Incubation of the thrombomodulin-enzyme complex with phospholipid vesicles caused an increase in the protein C activation rates. The kinetic constants for protein C activation in the presence of phospholipid are virtually identical for these enzyme-thrombomodulin complexes

  13. Why do children think they get discomfort related to daily activities?

    Science.gov (United States)

    Coleman, Jemma; Straker, Leon; Ciccarelli, Marina

    2009-01-01

    Children commonly report musculoskeletal discomfort related to different activities such as computer use, playing electronic games, watching TV, reading, and performing physical and hand intensive activities. Discomfort can result in disability and is a strong predictor of future discomfort in adulthood. Adult beliefs regarding discomfort can affect the level of disability and are modifiable. Children's beliefs regarding discomfort could potentially be modified to minimise disability related to musculoskeletal disorders. The aim of this study was to describe children's beliefs about why they experience musculoskeletal discomfort, both in general and related to specific activities. Eighty eight school children completed questionnaires on frequency and usual duration of nine activities, whether they had felt discomfort and what they believed was the cause of any discomfort in relation to those activities. The most common activity was TV watching, and most activities were performed for 1 hour or shorter. Bad posture and doing too much of a certain activity were the most common beliefs regarding reasons for discomfort. This study shows that children are developing beliefs that tend to reflect scientific knowledge about risk factors. These beliefs could be incorporated into preventative health interventions.

  14. 12 CFR 225.126 - Activities not closely related to banking.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Activities not closely related to banking. 225.126 Section 225.126 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE... Financial Holding Companies Interpretations § 225.126 Activities not closely related to banking. Pursuant to...

  15. 22 CFR 1203.735-211 - Activities relating to private organizations and politics.

    Science.gov (United States)

    2010-04-01

    ... politics. 1203.735-211 Section 1203.735-211 Foreign Relations UNITED STATES INTERNATIONAL DEVELOPMENT... Employees § 1203.735-211 Activities relating to private organizations and politics. (a) Definition. For the... engage in any form of political activity in any foreign country. (h) Activities relating to U.S. politics...

  16. Confirmatory factor analysis applied to the Force Concept Inventory

    Science.gov (United States)

    Eaton, Philip; Willoughby, Shannon D.

    2018-06-01

    In 1995, Huffman and Heller used exploratory factor analysis to draw into question the factors of the Force Concept Inventory (FCI). Since then several papers have been published examining the factors of the FCI on larger sets of student responses and understandable factors were extracted as a result. However, none of these proposed factor models have been verified to not be unique to their original sample through the use of independent sets of data. This paper seeks to confirm the factor models proposed by Scott et al. in 2012, and Hestenes et al. in 1992, as well as another expert model proposed within this study through the use of confirmatory factor analysis (CFA) and a sample of 20 822 postinstruction student responses to the FCI. Upon application of CFA using the full sample, all three models were found to fit the data with acceptable global fit statistics. However, when CFA was performed using these models on smaller sample sizes the models proposed by Scott et al. and Eaton and Willoughby were found to be far more stable than the model proposed by Hestenes et al. The goodness of fit of these models to the data suggests that the FCI can be scored on factors that are not unique to a single class. These scores could then be used to comment on how instruction methods effect the performance of students along a single factor and more in-depth analyses of curriculum changes may be possible as a result.

  17. Integrated Fuel-Coolant Interaction (IFCI 7.0) Code User's Manual

    Energy Technology Data Exchange (ETDEWEB)

    Young, Michael F.

    1999-05-01

    The integrated fuel-coolant interaction (IFCI) computer code is being developed at Sandia National Laboratories to investigate the fuel-coolant interaction (FCI) problem at large scale using a two-dimensional, three-field hydrodynamic framework and physically based models. IFCI will be capable of treating all major FCI processes in an integrated manner. This document is a description of IFCI 7.0. The user's manual describes the hydrodynamic method and physical models used in IFCI 7.0. Appendix A is an input manual provided for the creation of working decks.

  18. Integrated Fuel-Coolant Interaction (IFCI 7.0) Code User's Manual

    International Nuclear Information System (INIS)

    Young, Michael F.

    1999-01-01

    The integrated fuel-coolant interaction (IFCI) computer code is being developed at Sandia National Laboratories to investigate the fuel-coolant interaction (FCI) problem at large scale using a two-dimensional, three-field hydrodynamic framework and physically based models. IFCI will be capable of treating all major FCI processes in an integrated manner. This document is a description of IFCI 7.0. The user's manual describes the hydrodynamic method and physical models used in IFCI 7.0. Appendix A is an input manual provided for the creation of working decks

  19. Meat Juice Serology and Improved Food Chain Information as Control Tools for Pork-Related Public Health Hazards.

    Science.gov (United States)

    Felin, E; Jukola, E; Raulo, S; Fredriksson-Ahomaa, M

    2015-09-01

    The seroprevalence of Salmonella spp., pathogenic Yersinia spp., Toxoplasma gondii and Trichinella spp. was studied in 1353 finishing pigs from 259 farms that were allocated according to farm types: large fattening farms (≥ 1000 pig places), small fattening farms (Food Safety Authority (EFSA) considers Salmonella spp., Yersinia enterocolitica, T. gondii and Trichinella spp. as the most relevant biological hazards in the context of meat inspection of pigs. The seroprevalence of these important zoonotic pathogens was low in Finland, except that of Yersinia. The seroprevalence of Toxoplasma was significantly higher in pigs originating from small-scale fattening farms (P food chain information (FCI). © 2014 Blackwell Verlag GmbH.

  20. 29 CFR 779.205 - Enterprise must consist of “related activities.”

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Enterprise must consist of ârelated activities.â 779.205... STANDARDS ACT AS APPLIED TO RETAILERS OF GOODS OR SERVICES Employment to Which the Act May Apply; Enterprise Coverage Related Activities § 779.205 Enterprise must consist of “related activities.” The enterprise must...

  1. Gaming is related to enhanced working memory performance and task-related cortical activity.

    Science.gov (United States)

    Moisala, M; Salmela, V; Hietajärvi, L; Carlson, S; Vuontela, V; Lonka, K; Hakkarainen, K; Salmela-Aro, K; Alho, K

    2017-01-15

    Gaming experience has been suggested to lead to performance enhancements in a wide variety of working memory tasks. Previous studies have, however, mostly focused on adult expert gamers and have not included measurements of both behavioral performance and brain activity. In the current study, 167 adolescents and young adults (aged 13-24 years) with different amounts of gaming experience performed an n-back working memory task with vowels, with the sensory modality of the vowel stream switching between audition and vision at random intervals. We studied the relationship between self-reported daily gaming activity, working memory (n-back) task performance and related brain activity measured using functional magnetic resonance imaging (fMRI). The results revealed that the extent of daily gaming activity was related to enhancements in both performance accuracy and speed during the most demanding (2-back) level of the working memory task. This improved working memory performance was accompanied by enhanced recruitment of a fronto-parietal cortical network, especially the dorsolateral prefrontal cortex. In contrast, during the less demanding (1-back) level of the task, gaming was associated with decreased activity in the same cortical regions. Our results suggest that a greater degree of daily gaming experience is associated with better working memory functioning and task difficulty-dependent modulation in fronto-parietal brain activity already in adolescence and even when non-expert gamers are studied. The direction of causality within this association cannot be inferred with certainty due to the correlational nature of the current study. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Psychosocial Variables Related to Why Women are Less Active than Men and Related Health Implications

    OpenAIRE

    Edwards, Elizabeth Skidmore; Sackett, Sarah Carson

    2016-01-01

    This article reviews psychosocial influences on women's participation in physical activity as they differ from men and how associated activity differences impact women's risk for a number of chronic diseases. This topic directly aligns with the mission of this special edition related to disparities in women's health as the typically lower level of physical activity in females directly impacts their health. On average, females participate in physical activity at lower rates than their male cou...

  3. Health-related aspects of objectively measured daily physical activity in children

    DEFF Research Database (Denmark)

    Dencker, Magnus; Andersen, Lars Bo

    2008-01-01

    It is well established that physical inactivity in adults is associated with increased mortality and morbidity. Whether daily physical activity level is related to risk factors for cardiovascular disease (CVD) in children has been debated. Furthermore, objective data on the habitual daily physica...... activity. This review summarizes recently published studies that have used accelerometers to measure daily physical activity in children and related activity data to known risk factors for CVD.......It is well established that physical inactivity in adults is associated with increased mortality and morbidity. Whether daily physical activity level is related to risk factors for cardiovascular disease (CVD) in children has been debated. Furthermore, objective data on the habitual daily physical...... activity in children have at large been scarce in the literature. The main reason for this is the fact that daily physical activity is very difficult to measure in children. In recent years, a new device, the accelerometer, has emerged as a frequently used instrument for the measurement of daily physical...

  4. Suprathreshold Heat Pain Response Predicts Activity-Related Pain, but Not Rest-Related Pain, in an Exercise-Induced Injury Model

    Science.gov (United States)

    Coronado, Rogelio A.; Simon, Corey B.; Valencia, Carolina; Parr, Jeffrey J.; Borsa, Paul A.; George, Steven Z.

    2014-01-01

    Exercise-induced injury models are advantageous for studying pain since the onset of pain is controlled and both pre-injury and post-injury factors can be utilized as explanatory variables or predictors. In these studies, rest-related pain is often considered the primary dependent variable or outcome, as opposed to a measure of activity-related pain. Additionally, few studies include pain sensitivity measures as predictors. In this study, we examined the influence of pre-injury and post-injury factors, including pain sensitivity, for induced rest and activity-related pain following exercise induced muscle injury. The overall goal of this investigation was to determine if there were convergent or divergent predictors of rest and activity-related pain. One hundred forty-three participants provided demographic, psychological, and pain sensitivity information and underwent a standard fatigue trial of resistance exercise to induce injury of the dominant shoulder. Pain at rest and during active and resisted shoulder motion were measured at 48- and 96-hours post-injury. Separate hierarchical models were generated for assessing the influence of pre-injury and post-injury factors on 48- and 96-hour rest-related and activity-related pain. Overall, we did not find a universal predictor of pain across all models. However, pre-injury and post-injury suprathreshold heat pain response (SHPR), a pain sensitivity measure, was a consistent predictor of activity-related pain, even after controlling for known psychological factors. These results suggest there is differential prediction of pain. A measure of pain sensitivity such as SHPR appears more influential for activity-related pain, but not rest-related pain, and may reflect different underlying processes involved during pain appraisal. PMID:25265560

  5. Workplace harassment, active coping, and alcohol-related outcomes.

    Science.gov (United States)

    Richman, J A; Rospenda, K M; Flaherty, J A; Freels, S

    2001-01-01

    While sexual harassment and generalized workplace abuse (GWA) have been linked with alcohol use and abuse, active problem-focused coping has been shown to lessen vulnerability to deleterious mental health consequences of varied social stressors. At the same time, active coping is relatively more efficacious in response to stressors, which are amenable to change by personal actions. However, the moderating role that coping plays in relation to harassment and drinking is unknown. Using data from a two-wave survey of university employees (N=2038), we addressed the extent to which (1) active coping was utilized by harassed and abused employees, (2) whether coping impacted on the continuation or cessation of harassment and abuse, and (3) the extent to which nonsuccessful coping was predictive of alcohol use and abuse. Active coping had no significant impact on the ability to end harassing or abusive experiences. Moreover, the use of problem-focused coping that was unsuccessful predicted some drinking outcomes for both men and women, controlling for Wave I drinking and sociodemographic characteristics. The data suggest that increased institutional attention to the prevention of workplace harassment and abuse might impact on decreasing alcohol use and abuse.

  6. Food-Related Odors Activate Dopaminergic Brain Areas

    Directory of Open Access Journals (Sweden)

    Agnieszka Sorokowska

    2017-12-01

    Full Text Available Food-associated cues of different sensory categories have often been shown to be a potent elicitor of cerebral activity in brain reward circuits. Smells influence and modify the hedonic qualities of eating experience, and in contrast to smells not associated with food, perception of food-associated odors may activate dopaminergic brain areas. In this study, we aimed to verify previous findings related to the rewarding value of food-associated odors by means of an fMRI design involving carefully preselected odors of edible and non-edible substances. We compared activations generated by three food and three non-food odorants matching in terms of intensity, pleasantness and trigeminal qualities. We observed that for our mixed sample of 30 hungry and satiated participants, food odors generated significantly higher activation in the anterior cingulate cortex (right and left, insula (right, and putamen (right than non-food odors. Among hungry subjects, regardless of the odor type, we found significant activation in the ventral tegmental area in response to olfactory stimulation. As our stimuli were matched in terms of various perceptual qualities, this result suggests that edibility of an odor source indeed generates specific activation in dopaminergic brain areas.

  7. Expected reward modulates encoding-related theta activity before an event.

    Science.gov (United States)

    Gruber, Matthias J; Watrous, Andrew J; Ekstrom, Arne D; Ranganath, Charan; Otten, Leun J

    2013-01-01

    Oscillatory brain activity in the theta frequency range (4-8 Hz) before the onset of an event has been shown to affect the likelihood of successfully encoding the event into memory. Recent work has also indicated that frontal theta activity might be modulated by reward, but it is not clear how reward expectancy, anticipatory theta activity, and memory formation might be related. Here, we used scalp electroencephalography (EEG) to assess the relationship between these factors. EEG was recorded from healthy adults while they memorized a series of words. Each word was preceded by a cue that indicated whether a high or low monetary reward would be earned if the word was successfully remembered in a later recognition test. Frontal theta power between the presentation of the reward cue and the onset of a word was predictive of later memory for the word, but only in the high reward condition. No theta differences were observed before word onset following low reward cues. The magnitude of prestimulus encoding-related theta activity in the high reward condition was correlated with the number of high reward words that were later confidently recognized. These findings provide strong evidence for a link between reward expectancy, theta activity, and memory encoding. Theta activity before event onset seems to be especially important for the encoding of motivationally significant stimuli. One possibility is that dopaminergic activity during reward anticipation mediates frontal theta activity related to memory. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. A systematic review of financial incentives for physical activity: The effects on physical activity and related outcomes

    OpenAIRE

    Barte, J.C.M.; Wendel-Vos, G.C.W.

    2017-01-01

    The aim of this review is to give an overview of the available evidence on the effects of financial incentives to stimulate physical activity. Therefore, a systematic literature search was performed for randomized trials that investigate the effects of physical-activity-related financial incentives for individuals. Twelve studies with unconditional incentives (eg, free membership sport facility) and conditional incentives (ie, rewards for reaching physical-activity goals) related to physical ...

  9. Structure and sociodemographis characteristics of the family climate in Vojvodina

    Directory of Open Access Journals (Sweden)

    Mihić Ivana

    2006-01-01

    Full Text Available Research presented in this paper aimed to investigate psychometric characteristics and factor structure of Family Climate Inventory (FCI Kurdek et al., 1995, as well as the sociodemographic correlates of the quality of family environment operacionalized by this scale. The research sample consisted of 561 adolescents (average age 16. Four factores were extracted.Total variance explained by these four factors was 62. 29%. First factor has been defined as Acceptance, the second (Autonomy considers the estimated level of independence between family members. The third factor Conflicts implies frequency and influence of conflict situations and relations within the family. The fourth isolated factor- Supervision, was the dimension of original FCI scale, but has shown poor metric characteristics in our sample, and has been excluded from further analysis. The reduced Family Climate Inventory consists of 18 items, and has good psychometric characteristics (Cronbah a =.94. Family climate is assessed as better in dual earning families with egalitarian division of parental roles and household labor. Adolescents from rural families describe their family environment as better in quality.

  10. Stereotype activation is unintentional: Behavioural and event-related potenials evidence.

    Science.gov (United States)

    Wang, Pei; Yang, Ya-Ping; Tan, Chen-Hao; Zhao, Xiang-Xia; Liu, Yong-He; Lin, Chong-De

    2016-04-01

    In this study, a priming Stroop paradigm was used to determine whether stereotype activation is unintentional. Priming conditions (priming/no-priming) and the relationship between priming and target (consistent/inconsistent/no-relation) were the independent variables; accuracy, reaction time and N400 amplitude were used as dependent variables. The reaction time revealed that stereotype activation is, to some extent, unintentional. Furthermore, the event-related potenial (ERP) results showed that N400 amplitude was larger for inconsistent conditions than for consistent conditions. This result supported the notion that stereotype activation is an unintentional and automatic process. © 2015 International Union of Psychological Science.

  11. Employability and work-related learning activities in higher education

    DEFF Research Database (Denmark)

    Magnell, Marie; Kolmos, Anette

    2017-01-01

    The focus of this paper is on how academic staff perceive their roles and responsibilities regarding work-related learning, and how they approach and implement work-related learning activities in curricula across academic environments in higher education. The study is based on case studies...

  12. Beyond recreational physical activity: examining occupational and household activity, transportation activity, and sedentary behavior in relation to postmenopausal breast cancer risk.

    Science.gov (United States)

    George, Stephanie M; Irwin, Melinda L; Matthews, Charles E; Mayne, Susan T; Gail, Mitchell H; Moore, Steven C; Albanes, Demetrius; Ballard-Barbash, Rachel; Hollenbeck, Albert R; Schatzkin, Arthur; Leitzmann, Michael F

    2010-11-01

    We prospectively examined nonrecreational physical activity and sedentary behavior in relation to breast cancer risk among 97 039 postmenopausal women in the National Institutes of Health-AARP Diet and Health Study. We identified 2866 invasive and 570 in situ breast cancer cases recorded between 1996 and 2003 and used Cox proportional hazards regression to estimate multivariate relative risks (RRs) and 95% confidence intervals (CIs). Routine activity during the day at work or at home that included heavy lifting or carrying versus mostly sitting was associated with reduced risk of invasive breast cancer (RR = 0.62; 95% CI = 0.42, 0.91; P(trend) = .024). Routine activity during the day at work or home may be related to reduced invasive breast cancer risk. Domains outside of recreation time may be attractive targets for increasing physical activity and reducing sedentary behavior among postmenopausal women.

  13. Accurate quantum chemical calculations

    Science.gov (United States)

    Bauschlicher, Charles W., Jr.; Langhoff, Stephen R.; Taylor, Peter R.

    1989-01-01

    An important goal of quantum chemical calculations is to provide an understanding of chemical bonding and molecular electronic structure. A second goal, the prediction of energy differences to chemical accuracy, has been much harder to attain. First, the computational resources required to achieve such accuracy are very large, and second, it is not straightforward to demonstrate that an apparently accurate result, in terms of agreement with experiment, does not result from a cancellation of errors. Recent advances in electronic structure methodology, coupled with the power of vector supercomputers, have made it possible to solve a number of electronic structure problems exactly using the full configuration interaction (FCI) method within a subspace of the complete Hilbert space. These exact results can be used to benchmark approximate techniques that are applicable to a wider range of chemical and physical problems. The methodology of many-electron quantum chemistry is reviewed. Methods are considered in detail for performing FCI calculations. The application of FCI methods to several three-electron problems in molecular physics are discussed. A number of benchmark applications of FCI wave functions are described. Atomic basis sets and the development of improved methods for handling very large basis sets are discussed: these are then applied to a number of chemical and spectroscopic problems; to transition metals; and to problems involving potential energy surfaces. Although the experiences described give considerable grounds for optimism about the general ability to perform accurate calculations, there are several problems that have proved less tractable, at least with current computer resources, and these and possible solutions are discussed.

  14. Relationship between cancer-related fatigue and physical activity in inpatient cancer rehabilitation.

    Science.gov (United States)

    Kummer, Franziska; Catuogno, Silvio; Perseus, Josef M; Bloch, Wilhelm; Baumann, Freerk T

    2013-08-01

    Fatigue is a serious problem for the majority of patients with cancer. In this context, several studies have shown benefits of physical activity during and following treatment. However, uncertainties remain regarding the optimal type and duration of physical activity. Therefore, this study examined the relationship between cancer-related fatigue and physical activity in the course of inpatient rehabilitation. Fatigue (Multidimensional Fatigue Inventory) and physical activity (Freiburg Questionnaire of Physical Activity) were assessed in a consecutive series of 35 patients with cancer attending oncological inpatient rehabilitation during a six-month study period. The three-week rehabilitation program included daily exercise therapy consisting of aerobic endurance training, moderate resistance training, coordination exercises, relaxation training and individual physiotherapy. At discharge, a significant improvement in each dimension of cancer-related fatigue (p=0.001-0.003) and a significant increase of physical activity levels (p=0.001) were observed. A small, but significant negative correlation was found between cancer-related fatigue and the level of physical activity (R=-0.438, p=0.004). The largest effects were associated with a weekly energy expenditure of 3000 kcal through physical activity. The results support a non-linear dose-response relationship between cancer-related fatigue and physical activity. Since this is the first study providing specific exercise recommendations for an effective treatment of cancer-related fatigue in the context of inpatient rehabilitation, further research is required to validate the observed trends.

  15. Physical activity behavior and related characteristics of highly active eighth-grade girls.

    Science.gov (United States)

    Taverno Ross, Sharon E; Dowda, Marsha; Beets, Michael W; Pate, Russell R

    2013-06-01

    Although girls are generally less physically active than boys, some girls regularly engage in high levels of physical activity (PA); however, very little is known about these girls and how they differ from those who are less physically active. This study examined the PA behavior and related characteristics of highly active adolescent girls and compared them with those who are less active. Data from 1,866 eighth-grade girls from six field centers across the United States participating in the Trial of Activity for Adolescent Girls (TAAG) were included in the present analysis. Mixed-model analysis of variance examined differences in sociodemographic, anthropometric, psychosocial, and physical activity (accelerometry and self-report) variables between high- and low-active girls; effect sizes were calculated for the differences. High-active girls were taller, had lower body mass indices and body fat, and were less sedentary. High-active girls scored higher on self-efficacy, enjoyment of PA, self-management strategies, outcome-expectancy value, and support from family and friends than low-active girls. Low-active girls participated in more leisure time and educational sedentary activities than high-active girls. High-active girls participated in more PA classes/lessons outside of school, team sports, and individual sports. They were also more likely to participate in sports in an organized setting in the community or at school than low-active girls. Health promotion efforts should focus on decreasing the amount of time girls spend in sedentary activities and replacing that time with organized PA opportunities; such efforts should seek to minimize perceived barriers and increase self-efficacy and support for PA. Copyright © 2013 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  16. Error-Related Activity and Correlates of Grammatical Plasticity

    Science.gov (United States)

    Davidson, Doug J.; Indefrey, Peter

    2011-01-01

    Cognitive control involves not only the ability to manage competing task demands, but also the ability to adapt task performance during learning. This study investigated how violation-, response-, and feedback-related electrophysiological (EEG) activity changes over time during language learning. Twenty-two Dutch learners of German classified short prepositional phrases presented serially as text. The phrases were initially presented without feedback during a pre-test phase, and then with feedback in a training phase on two separate days spaced 1 week apart. The stimuli included grammatically correct phrases, as well as grammatical violations of gender and declension. Without feedback, participants’ classification was near chance and did not improve over trials. During training with feedback, behavioral classification improved and violation responses appeared to both types of violation in the form of a P600. Feedback-related negative and positive components were also present from the first day of training. The results show changes in the electrophysiological responses in concert with improving behavioral discrimination, suggesting that the activity is related to grammar learning. PMID:21960979

  17. LETTERS AND COMMENTS: Comment on 'The effects of students' reasoning abilities on conceptual understanding and problem-solving skills in introductory mechanics'

    Science.gov (United States)

    Coletta, Vincent P.; Phillips, Jeffrey A.; Savinainen, Antti; Steinert, Jeffrey J.

    2008-09-01

    In a recent article, Ates and Cataloglu (2007 Eur. J. Phys. 28 1161-71), in analysing results for a course in introductory mechanics for prospective science teachers, found no statistically significant correlation between students' pre-instruction scores on the Lawson classroom test of scientific reasoning ability (CTSR) and post-instruction scores on the force concept inventory (FCI). As a possible explanation, the authors suggest that the FCI does not probe for skills required to determine reasoning abilities. Our previously published research directly contradicts the authors' finding. We summarize our research and present a likely explanation for their observation of no correlation.

  18. Fuel-coolant interaction-phenomena under prompt burst conditions

    International Nuclear Information System (INIS)

    Jacobs, H.; Young, M.F.; Reil, K.O.

    1979-01-01

    The Prompt Burst Energetics (PBE) experiments conducted at Sandia Laboratories are a series of in-pile tests with fresh uranium oxide or uranium carbide fuel pins in stagnant sodium. Fuel-coolant-interactions in PBE-9S (oxide/sodium system) and PBE-SG2 (carbide/sodium) have been analyzed with the MURTI parametric FCI code. The purpose is to gain insight into possible FCI scenarios in the experiments and sensitivity of results to input parameters. Results are in approximate agreement for the second (triggered) event in PBE-9S (32 MPa peak) and the initial interaction in PBE-SG2

  19. Integrated Fuel-Coolant Interaction (IFCI 6.0) code

    International Nuclear Information System (INIS)

    Davis, F.J.; Young, M.F.

    1994-04-01

    The integrated Fuel-Coolant interaction (IFCI) computer code is being developed at Sandia National Laboratories to investigate the fuel-coolant interaction (FCI) problem at large scale using a two-dimensional, four-field hydrodynamic framework and physically based models. IFCI will be capable of treating all major FCI processes in an integrated manner. This document is a product of the effort to generate a stand-alone version of IFCI, IFCI 6.0. The User's Manual describes in detail the hydrodynamic method and physical models used in IFCI 6.0. Appendix A is an input manual, provided for the creation of working decks

  20. Fuel-coolant interaction-phenomena under prompt burst conditions. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, H.; Young, M.F.; Reil, K.O.

    1979-01-01

    The Prompt Burst Energetics (PBE) experiments conducted at Sandia Laboratories are a series of in-pile tests with fresh uranium oxide or uranium carbide fuel pins in stagnant sodium. Fuel-coolant-interactions in PBE-9S (oxide/sodium system) and PBE-SG2 (carbide/sodium) have been analyzed with the MURTI parametric FCI code. The purpose is to gain insight into possible FCI scenarios in the experiments and sensitivity of results to input parameters. Results are in approximate agreement for the second (triggered) event in PBE-9S (32 MPa peak) and the initial interaction in PBE-SG2 (190 MPa peak).

  1. Kinesiophobia in relation to physical activity in chronic neck pain.

    Science.gov (United States)

    Demirbüken, İlkşan; Özgül, Bahar; Kuru Çolak, Tuğba; Aydoğdu, Onur; Sarı, Zübeyir; Yurdalan, Saadet Ufuk

    2016-01-01

    Little research is available concerning physical activity and its determinants in people with chronic neck pain. To explore the relation between kinesiophobia and physical activity and gender effect on these relations in people with chronic neck pain. Ninety-nine subjects (34 men and 65 women) with chronic neck pain were participated in the study. Pain intensity was assessed with Visual Analog Scale and kinesiophobia degree was determined by using Tampa Scale of Kinesiophobia. Level of physical activity was assessed with short form of the International Physical Activity Questionnaire. There was no statistically correlation between neck pain intensity and kinesiophobia degree (p= 0.246, r= 0.123) and physical activity level (p= 0.432, r= -0.083). It was also found that kinesiophobia degree was not correlated to physical activity level (p= 0.148, r= -0.153). There was a negative correlation between kinesiophobia degree and physical activity level only for women, not for men (p= 0.011, r= -0.318). Our results showed that although people with chronic neck pain reported higher pain intensity and fear of movement, pain intensity and kinesiophobia degree did not associate to their physical activity levels. It can be speculated that high kinesiophobia degrees cause low physical activity levels for women, but not for men.

  2. Striatal Activity and Reward Relativity: Neural Signals Encoding Dynamic Outcome Valuation.

    Science.gov (United States)

    Webber, Emily S; Mankin, David E; Cromwell, Howard C

    2016-01-01

    The striatum is a key brain region involved in reward processing. Striatal activity has been linked to encoding reward magnitude and integrating diverse reward outcome information. Recent work has supported the involvement of striatum in the valuation of outcomes. The present work extends this idea by examining striatal activity during dynamic shifts in value that include different levels and directions of magnitude disparity. A novel task was used to produce diverse relative reward effects on a chain of instrumental action. Rats ( Rattus norvegicus ) were trained to respond to cues associated with specific outcomes varying by food pellet magnitude. Animals were exposed to single-outcome sessions followed by mixed-outcome sessions, and neural activity was compared among identical outcome trials from the different behavioral contexts. Results recording striatal activity show that neural responses to different task elements reflect incentive contrast as well as other relative effects that involve generalization between outcomes or possible influences of outcome variety. The activity that was most prevalent was linked to food consumption and post-food consumption periods. Relative encoding was sensitive to magnitude disparity. A within-session analysis showed strong contrast effects that were dependent upon the outcome received in the immediately preceding trial. Significantly higher numbers of responses were found in ventral striatum linked to relative outcome effects. Our results support the idea that relative value can incorporate diverse relationships, including comparisons from specific individual outcomes to general behavioral contexts. The striatum contains these diverse relative processes, possibly enabling both a higher information yield concerning value shifts and a greater behavioral flexibility.

  3. The median preoptic nucleus reciprocally modulates activity of arousal-related and sleep-related neurons in the perifornical lateral hypothalamus.

    Science.gov (United States)

    Suntsova, Natalia; Guzman-Marin, Ruben; Kumar, Sunil; Alam, Md Noor; Szymusiak, Ronald; McGinty, Dennis

    2007-02-14

    The perifornical-lateral hypothalamic area (PF/LH) contains neuronal groups playing an important role in control of waking and sleep. Among the brain regions that regulate behavioral states, one of the strongest sources of projections to the PF/LH is the median preoptic nucleus (MnPN) containing a sleep-active neuronal population. To evaluate the role of MnPN afferents in the control of PF/LH neuronal activity, we studied the responses of PF/LH cells to electrical stimulation or local chemical manipulation of the MnPN in freely moving rats. Single-pulse electrical stimulation evoked responses in 79% of recorded PF/LH neurons. No cells were activated antidromically. Direct and indirect transsynaptic effects depended on sleep-wake discharge pattern of PF/LH cells. The majority of arousal-related neurons, that is, cells discharging at maximal rates during active waking (AW) or during AW and rapid eye movement (REM) sleep, exhibited exclusively or initially inhibitory responses to stimulation. Sleep-related neurons, the cells with elevated discharge during non-REM and REM sleep or selectively active in REM sleep, exhibited exclusively or initially excitatory responses. Activation of the MnPN via microdialytic application of L-glutamate or bicuculline resulted in reduced discharge of arousal-related and in excitation of sleep-related PF/LH neurons. Deactivation of the MnPN with muscimol caused opposite effects. The results indicate that the MnPN contains subset(s) of neurons, which exert inhibitory control over arousal-related and excitatory control over sleep-related PF/LH neurons. We hypothesize that MnPN sleep-active neuronal group has both inhibitory and excitatory outputs that participate in the inhibitory control of arousal-promoting PF/LH mechanisms.

  4. Physical activity in relation to selected physical health components ...

    African Journals Online (AJOL)

    The aim of this study was to determine the relation between physical activity and selected physical health components. A total of 9860 employees of a financial institution in South Africa, between the ages 18 and 64 (x̄ =35.3 ± 18.6 years), voluntary participated in the study. Health risk factors and physical activity was ...

  5. Non-Relative Value Unit-Generating Activities Represent One-Fifth of Academic Neuroradiologist Productivity.

    Science.gov (United States)

    Wintermark, M; Zeineh, M; Zaharchuk, G; Srivastava, A; Fischbein, N

    2016-07-01

    A neuroradiologist's activity includes many tasks beyond interpreting relative value unit-generating imaging studies. Our aim was to test a simple method to record and quantify the non-relative value unit-generating clinical activity represented by consults and clinical conferences, including tumor boards. Four full-time neuroradiologists, working an average of 50% clinical and 50% academic activity, systematically recorded all the non-relative value unit-generating consults and conferences in which they were involved during 3 months by using a simple, Web-based, computer-based application accessible from smartphones, tablets, or computers. The number and type of imaging studies they interpreted during the same period and the associated relative value units were extracted from our billing system. During 3 months, the 4 neuroradiologists working an average of 50% clinical activity interpreted 4241 relative value unit-generating imaging studies, representing 8152 work relative value units. During the same period, they recorded 792 non-relative value unit-generating study reviews as part of consults and conferences (not including reading room consults), representing 19% of the interpreted relative value unit-generating imaging studies. We propose a simple Web-based smartphone app to record and quantify non-relative value unit-generating activities including consults, clinical conferences, and tumor boards. The quantification of non-relative value unit-generating activities is paramount in this time of a paradigm shift from volume to value. It also represents an important tool for determining staffing levels, which cannot be performed on the basis of relative value unit only, considering the importance of time spent by radiologists on non-relative value unit-generating activities. It may also influence payment models from medical centers to radiology departments or practices. © 2016 by American Journal of Neuroradiology.

  6. The relation between self-esteem, sexual activity, and pregnancy.

    Science.gov (United States)

    Robinson, R B; Frank, D I

    1994-01-01

    This study examined self-esteem in relation to sexual behaviors which often result in teen pregnancy. A sample of 141 male and 172 female adolescents of racial diversity was surveyed to elicit levels of self-esteem, sexual activity, pregnancy and fatherhood status. The Coopersmith Self-Esteem Inventory was used as well to elicit qualitative data about self-esteem, demographics, and sexual activity. Analysis revealed no differences in the self-esteem of males vs. females. Further, sexual activity or virginity was not related to self-esteem in either males or females. Pregnant teens did not have different levels of self-esteem from the nonpregnant. However, males who had fathered a child had lower self-esteem than did nonfathers. The findings support a multifocused approach to sex education for pregnancy prevention and also emphasize a need to include males in both pregnancy prevention efforts as well as in further research on teen pregnancy.

  7. Objectively measured active travel and uses of activity-friendly neighborhood resources: Does change in use relate to change in physical activity and BMI?

    Directory of Open Access Journals (Sweden)

    Barbara B. Brown

    2017-12-01

    Full Text Available Few studies examine how objectively measured use of local physical activity resources contributes to objectively-measured healthy physical activity and weight changes over time. We utilized objective measures to test whether changes in active travel and uses of three physical activity (PA resources–parks, recreation centers, and transit– related to changes in PA and BMI. Adults (n=536 in Salt Lake City, UT, wore accelerometer and GPS units in 2012 and 2013, before and after neighborhood rail completion. Regression outcomes included accelerometer counts per minute (cpm, MVPA (moderate-to-vigorous activity minutes/10h accelerometer wear and measured BMI; key predictors were changes in active travel and PA resource uses (former and new uses. Significant results (all p<0.05 showed that increased active travel related to increased total PA (59.86cpm and 8.50 MVPA; decreased active travel related to decreased MVPA (−3.01 MVPA. Poorer outcomes were seen after discontinuing use of parks (−36.29cpm, −5.73 MVPA, and +0.44 BMI points, recreation centers (−6.18 MVPA, and transit (−48.14cpm, −5.43 MVPA, and +0.66 BMI. Healthier outcomes were seen after commencing use of parks (29.83cpm, 5.25 MVPA, recreation centers (44.63cpm and transit (38.44cpm, 4.17 MVPA, and −0.56 BMI. Transit and park/recreational center uses were unrelated, although park users were more likely to be recreation center users. Active travel and use of three neighborhood PA resources relate to healthy activity and could be fostered by policy and design. Keywords: Recreation center, Accelerometry, Active transport, Built environment, Parks, Global positioning system

  8. Public Relations and Propaganda: Restrictions on Executive Agency Activities

    National Research Council Canada - National Science Library

    Kosar, Kevin R

    2005-01-01

    Controversies recently have arisen over certain executive branch agencies' expenditures of appropriated funds on public relations activities, some of which have been characterized as propagandistic...

  9. Project Rio Blanco: detonation related activities. Final report

    International Nuclear Information System (INIS)

    1975-01-01

    Project Rio Blanco is described in relation to detonation, its history, execution, and results. Topics discussed include generalized site activities, emplacement well, explosive services and operations, operational safety, environmental protection program, seismic effects and damage claims, and add-on programs. (U.S.)

  10. Electrically active sodium-related defect centres in silicon

    DEFF Research Database (Denmark)

    Dahl, Espen; Madsbøll, J.; Søiland, A.-K.

    2013-01-01

    Electrically active defect centres related to sodium in silicon have been examined with deep level transient spectroscopy, and their recombination potential analysed with the microwave photoconductive decay technique. In order to investigate the entire silicon band gap for defect centres, both p-...

  11. NIC (Nuclear Industry in China) exhibition. Press file

    International Nuclear Information System (INIS)

    1998-01-01

    Framatome participated to the NIC exhibition which took place in Beijing (China) on March 1998. This press dossier was distributed to visitors. It presents in a first part the activities of the Framatome group in people's republic of China (new constructions (Daya Bay, Ling Ao project), technological cooperation and contracts in the nuclear domain, technology transfers in the domain of nuclear fuels, activities and daughter companies in the domain of industrial equipments, Framatome Connectors International (FCI) daughter company in the domain of connectors engineering). Then, the general activities of Framatome in the nuclear, industrial equipment, and connectors engineering domains are summarized in the next 3 parts. (J.S.)

  12. Relation of flare activity to the approach and separation of sunspots in an active region and to its magnetic properties

    International Nuclear Information System (INIS)

    Markova, E.

    1978-01-01

    The relation between the flare activity of active regions within the scope of a large complex and the magnetic gradients of these active regions and their daily variations is investigated in the interval of the exceptionally high flare activity occurring in June 1970. New indices, characterizing the active region, were defined, e.g., the instantaneous sunspot-area density and the instantaneous sunspot-number density. These indices were determined on the basis of measurements of the surface containing all sunspots of the complex of active regions enclosed by an envelope. An attempt was made to substitute the surface in the relation for the individual indices by distance. The daily variations of these indices were again compared with the flare activity and some mutual relations were derived. (author)

  13. The role of body-related self-conscious emotions in motivating women's physical activity.

    Science.gov (United States)

    Sabiston, Catherine M; Brunet, Jennifer; Kowalski, Kent C; Wilson, Philip M; Mack, Diane E; Crocker, Peter R E

    2010-08-01

    The purpose of this study was to test a model where body-related self-conscious emotions of shame, guilt, and pride were associated with physical activity regulations and behavior. Adult women (N = 389; M age = 29.82, SD = 15.20 years) completed a questionnaire assessing body-related pride, shame, and guilt, motivational regulations, and leisure-time physical activity. The hypothesized measurement and structural models were deemed adequate, as was a revised model examining shame-free guilt and guilt-free shame. In the revised structural model, body-related pride was positively significantly related to identified and intrinsic regulations. Body-related shame-free guilt was significantly associated with external, introjected, and identified regulations. Body-related guilt-free shame was significantly positively related to external and introjected regulation, and negatively associated with intrinsic regulation. Identified and intrinsic regulations were significantly positively related to physical activity (R2 = .62). These findings highlight the importance of targeting and understanding the realm of body-related self-conscious emotions and the associated links to regulations and physical activity behavior.

  14. Towards age/rotation/magnetic activity relation with seismology

    Directory of Open Access Journals (Sweden)

    Mathur Savita

    2015-01-01

    Full Text Available The knowledge of stellar ages directly impacts the characterization of a planetary system as it puts strong constraints on the moment when the system was born. Unfortunately, the determination of precise stellar ages is a very difficult task. Different methods can be used to do so (based on isochrones or chemical element abundances but they usually provide large uncertainties. During its evolution a star goes through processes leading to loss of angular momentum but also changes in its magnetic activity. Building rotation, magnetic, age relations would be an asset to infer stellar ages model independently. Several attempts to build empirical relations between rotation and age (namely gyrochronology were made with a focus on cluster stars where the age determination is easier and for young stars on the main sequence. For field stars, we can now take advantage of high-precision photometric observations where we can perform asteroseismic analyses to improve the accuracy of stellar ages. Furthermore, the variability in the light curves allow us to put strong constraints on the stellar rotation and magnetic activity. By combining these precise measurements, we are on the way of understanding and improving relations between magnetic activity, rotation, and age, in particular at different stages of stellar evolution. I will review the status on gyrochronology relationships based on observations of young cluster stars. Then I will focus on solar-like stars and describe the inferences on stellar ages, rotation, and magnetism that can be provided by high-quality photometric observations such as the ones of the Kepler mission, in particular through asteroseismic analyses.

  15. rCBF activation studies and neuronal circuitry related to vision

    NARCIS (Netherlands)

    deJong, BM

    Three principles of neuronal interaction within cortically distributed networks are discussed PET-rCBF activation methods provide an opportunity to acquire insight in the distribution of functionally related areas of the human brain in vivo. The distinction of visual areas, activated by either

  16. Exercising self-control increases relative left frontal cortical activation.

    Science.gov (United States)

    Schmeichel, Brandon J; Crowell, Adrienne; Harmon-Jones, Eddie

    2016-02-01

    Self-control refers to the capacity to override or alter a predominant response tendency. The current experiment tested the hypothesis that exercising self-control temporarily increases approach motivation, as revealed by patterns of electrical activity in the prefrontal cortex. Participants completed a writing task that did vs did not require them to exercise self-control. Then they viewed pictures known to evoke positive, negative or neutral affect. We assessed electroencephalographic (EEG) activity while participants viewed the pictures, and participants reported their trait levels of behavioral inhibition system (BIS) and behavioral activation system (BAS) sensitivity at the end of the study. We found that exercising (vs not exercising) self-control increased relative left frontal cortical activity during picture viewing, particularly among individuals with relatively higher BAS than BIS, and particularly during positive picture viewing. A similar but weaker pattern emerged during negative picture viewing. The results suggest that exercising self-control temporarily increases approach motivation, which may help to explain the aftereffects of self-control (i.e. ego depletion). © The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  17. Transit-Related Walking to Work in Promoting Physical Activity.

    Science.gov (United States)

    Yu, Chia-Yuan; Lin, Hsien-Chang

    2015-04-01

    Transit-related walking to work is a potential strategy for incorporating physical activity into daily life and promoting health benefits. This study estimated the transit-related walking time for work trips on the journey to and from work and examined the predictors of transit users who walked to/from transit and the workplace and those who walked 30 minutes or more per day. This study used the 2009 National Household Travel Survey and identified 772 subjects who took transit to/from work, 355 subjects who walked to/from transit and the workplace, and 145 subjects who walked 30 minutes or more per day among the 40,659 workers. Weighted logistic regressions were used for the analysis. Of the people who walked to/from transit and the workplace, 40.9% walked 30 minutes or more per day. The weighted logistic regressions revealed that low-income groups and workers living in high population density areas were more likely to walk to/from transit and the workplace. Workers living in high population density areas were more likely to walk 30 minutes or more per day. Transit-related walking to work provides an opportunity to increase physical activity levels and to meet the physical activity recommendations.

  18. Social Activity, School-Related Activity, and Anti-Substance Use Media Messages on Adolescent Tobacco and Alcohol Use.

    Science.gov (United States)

    Moon, Sung Seek; Rao, Uma

    2011-01-01

    In this article, we present the effects of three hypothesized protective factors: social activities, school-related activities, and anti-substance use media messages on adolescent tobacco and alcohol use. Data were drawn from the "Monitoring the Future" (MTF) research project, which was conducted by the Institute for Social Research at the University of Michigan. The sample included 2,551 twelfth-grade students. The results of the structural equation model showed that exposure to media anti-drug messages had an indirect negative effect on tobacco and alcohol use through school-related activity and social activity. The results suggest that comprehensive ecological interventions encompassing media, family, and school can increase on the preventive effects of adolescent's substance use.

  19. Topological and conventional order of spinless fermions in 2D lattices

    International Nuclear Information System (INIS)

    Kourtis, Stefanos

    2014-01-01

    After an introduction to the quintessential properties characterizing quantum Hall effects and topological phases in Part I of the present text, Part II has ventured into the less explored realm of correlated topological states in lattices. Haldane-like models were doped to fractional fillings of the gapped lower band and short-range interactions were used to induce lattice reincarnations of fractional quantum Hall states, called fractional Chern insulators (FCI). In Chapter 5, it was shown that band dispersion, which is usually taken to be zero to mimic Landau levels, can affect the competition between CDW and FCI states and actually favor the latter against the former. Furthermore, a first rudimentary look at the effect of magnetic disorder on a fractionally quantized topological invariant indicated that, even though the impact of disorder is intricate, the quantization of the invariant remains intact. The results presented in Chapter 6 demonstrate that FCI states do not necessarily need to come purely from a single Chern band, since strong interactions that mix bands seem to enhance their stability. The possibility for obtaining exotic correlated topological states was exemplified by the topological pinball liquid - a composite quantum state comprising of a CDW and a FCI - in Chapter 7. The conclusions of the preceding Chapters can be now set forth as answers to the questions posed in the beginning of Part II: - Are weak or strong interactions more favorable to correlated topological states? - Are insulators or semiconductors more suitable hosts? - Are dispersive or flat bands more susceptible to topological order? - Are correlated topological phases beyond the fractional quantum Hall paradigm possible in single-species many-particle systems?

  20. Topological and conventional order of spinless fermions in 2D lattices

    Energy Technology Data Exchange (ETDEWEB)

    Kourtis, Stefanos

    2014-10-15

    After an introduction to the quintessential properties characterizing quantum Hall effects and topological phases in Part I of the present text, Part II has ventured into the less explored realm of correlated topological states in lattices. Haldane-like models were doped to fractional fillings of the gapped lower band and short-range interactions were used to induce lattice reincarnations of fractional quantum Hall states, called fractional Chern insulators (FCI). In Chapter 5, it was shown that band dispersion, which is usually taken to be zero to mimic Landau levels, can affect the competition between CDW and FCI states and actually favor the latter against the former. Furthermore, a first rudimentary look at the effect of magnetic disorder on a fractionally quantized topological invariant indicated that, even though the impact of disorder is intricate, the quantization of the invariant remains intact. The results presented in Chapter 6 demonstrate that FCI states do not necessarily need to come purely from a single Chern band, since strong interactions that mix bands seem to enhance their stability. The possibility for obtaining exotic correlated topological states was exemplified by the topological pinball liquid - a composite quantum state comprising of a CDW and a FCI - in Chapter 7. The conclusions of the preceding Chapters can be now set forth as answers to the questions posed in the beginning of Part II: - Are weak or strong interactions more favorable to correlated topological states? - Are insulators or semiconductors more suitable hosts? - Are dispersive or flat bands more susceptible to topological order? - Are correlated topological phases beyond the fractional quantum Hall paradigm possible in single-species many-particle systems?.

  1. PPARgamma-PGC-1alpha activity is determinant of alcohol related breast cancer

    DEFF Research Database (Denmark)

    Koefoed Petersen, Rasmus; Benzon Larsen, Signe; Jensen, Ditte Marie

    2012-01-01

    Alcohol is a risk factor for postmenopausal breast cancer. One of several proposed mechanisms is that alcohol-related breast cancer is caused by increased sex hormone levels. PPARγ inhibits aromatase transcription in breast adipocytes. We reproduced previously found allele-specific effects...... of the wildtype Pro-allele of PPARG Pro12Ala in alcohol related breast cancer. In transiently transfected cells, transcriptional activation by PPARγ and the PPARγ-PGC-1α complex was inhibited by ethanol. PPARγ 12Ala-mediated transcription activation was not enhanced by PGC-1α, resulting in allele......-specific transcription activation by the PPARγ 12Pro-PGC-1α complex. Our results suggest that PPARγ and PGC-1α activity is an important determinant of alcohol related breast cancer....

  2. Experimental studies of thermal and chemical interactions between oxide and silicide nuclear fuels with water

    Energy Technology Data Exchange (ETDEWEB)

    farahani, A.A.; Corradini, M.L. [Univ. of Wisconsi, Madison, WI (United States)

    1995-09-01

    Given some transient power/cooling mismatch is a nuclear reactor and its inability to establish the necessary core cooling, energetic fuel-coolant interactions (FCI`s commonly called `vapor explosions`) could occur as a result of the core melting and coolant contact. Although a large number of studies have been done on energetic FCI`s, very few experiments have been performed with the actual fuel materials postulated to be produced in severe accidents. Because of the scarcity of well-characterized FCI data for uranium allows in noncommercial reactors (cermet and silicide fuels), we have conducted a series of experiments to provide a data base for the foregoing materials. An existing 1-D shock-tube facility was modified to handle depleted radioactive materials (U{sub 3}O{sub 8}-Al, and U{sub 3}Si{sub 2}-Al). Our objectives have been to determine the effects of the initial fuel composition and temperature and the driving pressure (triggering) on the explosion work output, dynamic pressures, transient temperatures, and the hydrogen production. Experimental results indicate limited energetics, mainly thermal interactions, for these fuel materials as compared to aluminum where more chemical reactions occur between the molten aluminum and water.

  3. The local atomic quasicrystal structure of the icosahedral Mg25Y11Zn64 alloy

    International Nuclear Information System (INIS)

    Bruehne, S; Uhrig, E; Gross, C; Assmus, W; Masadeh, A S; Billinge, S J L

    2005-01-01

    A local and medium range atomic structure model for the face centred icosahedral (fci) Mg 25 Y 11 Zn 64 alloy has been established in a sphere of r = 27 A. The model was refined by least squares techniques using the atomic pair distribution (PDF) function obtained from synchrotron powder diffraction. Three hierarchies of the atomic arrangement can be found: (i) five types of local coordination polyhedra for the single atoms, four of which are of Frank-Kasper type. In turn, they (ii) form a three-shell (Bergman) cluster containing 104 atoms, which is condensed sharing its outer shell with its neighbouring clusters, and (iii) a cluster connecting scheme corresponding to a three-dimensional tiling leaving space for a few glue atoms. Inside adjacent clusters, Y 8 cubes are tilted with respect to each other and thus allow for overall icosahedral symmetry. It is shown that the title compound is essentially isomorphic to its holmium analogue. Therefore, fci-Mg-Y-Zn can be seen as the representative structure type for the other rare earth analogues fci-Mg-Zn-RE (RE = Dy, Er, Ho, Tb) reported in the literature

  4. Doctoral scientists and engineers working in energy-related activities, 1981

    International Nuclear Information System (INIS)

    1983-04-01

    The Department of Energy has a responsibility to help ensure the supply of highly trained personnel by providing supply and demand information on energy-related manpower to public and private planners and the general public. This report provides information about the number and characteristics of doctoral-level engineers and scientists working primarily in energy-related activities. The data for the year 1981 are part of the information base for a program of continuing studies of the employment and utilization of all scientists and engineers involved in energy-related activities. Information from these studies will provide input to consideration of actions necessary to ensure that adequate numbers of qualified scientists and engineers are available, when needed, to develop the nation's energy resources and technologies

  5. The alpha activity of soils in relation to landscape development

    Energy Technology Data Exchange (ETDEWEB)

    Pepper, R G; Quirk, J P [Western Australia Univ., Nedlands. Dept. of Soil Science and Plant Nutrition

    1976-02-01

    The alpha activity of soils and the degree of the equilibrium of the thorium series has been related to the age of soils developed on a truncated laterite landscape in southwestern Australia. The uplift of the old lateritic plateau has formed a sequence of erosional and depositional surfaces which form the parent materials of the present-day soils. These surfaces because of their different relative ages have been subjected to different degrees of weathering and leaching. The alpha activity of the soils formed on these different landscape surfaces is influenced firstly by the amount of weathering that the surface has undergone, and secondly by the degree of leaching that the soil has undergone as evidenced by profile development. It has been found that the younger soils have higher alpha activities with the thorium series tending more towards equilibrium when compared with older soils, where the alpha activity is lower due to the leaching of the daughter nuclides from the profile.

  6. Physical activity is related to quality of life in older adults

    Directory of Open Access Journals (Sweden)

    Montgomery Polly S

    2006-06-01

    Full Text Available Abstract Background Physical activity is associated with health-related quality of life (HRQL in clinical populations, but less is known whether this relationship exists in older men and women who are healthy. Thus, this study determined if physical activity was related to HRQL in apparently healthy, older subjects. Methods Measures were obtained from 112 male and female volunteers (70 ± 8 years, mean ± SD recruited from media advertisements and flyers around the Norman, Oklahoma area. Data was collected using a medical history questionnaire, HRQL from the Medical Outcomes Survey short form-36 questionnaire, and physical activity level from the Johnson Space Center physical activity scale. Subjects were separated into either a higher physically active group (n = 62 or a lower physically active group (n = 50 according to the physical activity scale. Results The HRQL scores in all eight domains were significantly higher (p 0.05 between the two groups. Conclusion Healthy older adults who regularly participated in physical activity of at least moderate intensity for more than one hour per week had higher HRQL measures in both physical and mental domains than those who were less physically active. Therefore, incorporating more physical activity into the lifestyles of sedentary or slightly active older individuals may improve their HRQL.

  7. Scientific production about competitive intelligence of the School of Science Information of Brasília University

    OpenAIRE

    Perucchi, Valmira; Araújo Júnior, Rogério Henrique de

    2012-01-01

    A atual conjuntura tem gerado a necessidade das organizações manterem as melhores práticas de Inteligência Competitiva (IC). A IC é a atividade que objetiva a obtenção, análise e disseminação de informações, para auxiliar no processo decisório. Esta pesquisa foi desenvolvida para visualizar o cenário da produção científica sobre IC na Faculdade de Ciência da Informação (FCI) da Universidade de Brasília (UnB). Fazem parte da FCI os cursos de graduação em Arquivologia, Biblioteconomia e Museolo...

  8. Avaliação histomorfométrica da movimentação dentária induzida em ratos com força contínua, contínua interrompida e intermitente

    OpenAIRE

    Tondelli, Pedro Marcelo [UNESP

    2011-01-01

    Introdução: O presente trabalho apresenta uma metodologia para a movimentação dentária induzida (MDI) e avalia a quantidade de movimentação dentária, as condições ósseas, radiculares e periodontais, após o emprego de força contínua (FC), contínua interrompida (FCI) e intermitente (FI). Material e Métodos: Utilizou-se 54 ratos da linhagem Wistar, em grupos de FC, FCI e FI, nos períodos de 5, 7 e 9 dias. Inicialmente foram realizadas extrações dos incisivos superiores direitos de cada animal, e...

  9. High Tide, Low Tide. Ocean Related Curriculum Activities.

    Science.gov (United States)

    Snively, Gloria

    The ocean affects all of our lives. Therefore, awareness of and information about the interconnections between humans and oceans are prerequisites to making sound decisions for the future. Project ORCA (Ocean Related Curriculum Activities) has developed interdisciplinary curriculum materials designed to meet the needs of students and teachers…

  10. Altered Coupling between Motion-Related Activation and Resting-State Brain Activity in the Ipsilesional Sensorimotor Cortex after Cerebral Stroke

    Directory of Open Access Journals (Sweden)

    Jianping Hu

    2017-07-01

    Full Text Available Functional connectivity maps using resting-state functional magnetic resonance imaging (rs-fMRI can closely resemble task fMRI activation patterns, suggesting that resting-state brain activity may predict task-evoked activation or behavioral performance. However, this conclusion was mostly drawn upon a healthy population. It remains unclear whether the predictive ability of resting-state brain activity for task-evoked activation would change under different pathological conditions. This study investigated dynamic changes of coupling between patterns of resting-state functional connectivity (RSFC and motion-related activation in different stages of cerebral stroke. Twenty stroke patients with hand motor function impairment were involved. rs-fMRI and hand motion-related fMRI data were acquired in the acute, subacute, and early chronic stages of cerebral stroke on a 3-T magnetic resonance (MR scanner. Sixteen healthy participants were enrolled as controls. For each subject, an activation map of the affected hand was first created using general linear model analysis on task fMRI data, and then an RSFC map was determined by seeding at the peak region of hand motion activation during the intact hand task. We then measured the extent of coupling between the RSFC maps and motion-related activation maps. Dynamic changes of the coupling between the two fMRI maps were estimated using one-way repeated measures analysis of variance across the three stages. Moreover, imaging parameters were correlated with motor performances. Data analysis showed that there were different coupling patterns between motion-related activation and RSFC maps associating with the affected motor regions during the acute, subacute, and early chronic stages of stroke. Coupling strengths increased as the recovery from stroke progressed. Coupling strengths were correlated with hand motion performance in the acute stage, while coupling recovery was negatively correlated with the recovery

  11. Retrieval activates related words more than presentation.

    Science.gov (United States)

    Hausman, Hannah; Rhodes, Matthew G

    2018-03-23

    Retrieving information enhances learning more than restudying. One explanation of this effect is based on the role of mediators (e.g., sand-castle can be mediated by beach). Retrieval is hypothesised to activate mediators more than restudying, but existing tests of this hypothesis have had mixed results [Carpenter, S. K. (2011). Semantic information activated during retrieval contributes to later retention: Support for the mediator effectiveness hypothesis of the testing effect. Journal of Experimental Psychology: Learning, Memory, and Cognition, 37(6), 1547-1552. doi: 10.1037/a0024140 ; Lehman, M., & Karpicke, J. D. (2016). Elaborative retrieval: Do semantic mediators improve memory? Journal of Experimental Psychology: Learning, Memory, and Cognition, 42(10), 1573-1591. doi: 10.1037/xlm0000267 ]. The present experiments explored an explanation of the conflicting results, testing whether mediator activation during a retrieval attempt depends on the accessibility of the target information. A target was considered less versus more accessible when fewer versus more cues were given during retrieval practice (Experiments 1 and 2), when the target had been studied once versus three times initially (Experiment 3), or when the target could not be recalled versus could be recalled during retrieval practice (Experiments 1-3). A mini meta-analysis of all three experiments revealed a small effect such that retrieval activated mediators more than presentation, but mediator activation was not reliably related to target accessibility. Thus, retrieval may enhance learning by activating mediators, in part, but these results suggest the role of other processes, too.

  12. Physical activity and unplanned illness-related work absenteeism: Data from an employee wellness program.

    Science.gov (United States)

    Losina, Elena; Yang, Heidi Y; Deshpande, Bhushan R; Katz, Jeffrey N; Collins, Jamie E

    2017-01-01

    Illness-related absenteeism is a major threat to work productivity. Our objective was to assess the relationship between physical activity and unplanned illness-related absenteeism from work. We implemented physical activity program for sedentary non-clinician employees of a tertiary medical center. Financial rewards were available for reaching accelerometer-measured ambulatory physical activity goals over a 24-week period. We categorized participants into three groups based on mean levels of physical activity: low (0-74 min/week), medium (75-149 min/week) and meeting CDC guidelines (≥150 min/week). We built a multivariable Poisson regression model to evaluate the relationship between physical activity and rates of unplanned illness-related absenteeism. The sample consisted of 292 employees who participated in the program. Their mean age was 38 years (SD 11), 83% were female, and 38% were obese. Over the 24 intervention weeks, participants engaged in a mean of 90 min/week (SD 74) of physical activity and missed a mean of 14 hours of work (SD 38) due to illness. Unplanned absenteeism due to illness was associated with physical activity. As compared to the group meeting CDC guidelines, in multivariable analyses those in the medium physical activity group had a 2.4 (95% CI 1.3-4.5) fold higher rate of illness-related absenteeism and those in the lowest physical activity group had a 3.5 (95% CI 1.7-7.2) fold higher rate of illness-related absenteeism. Less physical activity was associated with more illness-related absenteeism. Workforce-based interventions to increase physical activity may thus be a promising vehicle to reduce unplanned illness-related absenteeism.

  13. Physical activity and unplanned illness-related work absenteeism: Data from an employee wellness program.

    Directory of Open Access Journals (Sweden)

    Elena Losina

    Full Text Available Illness-related absenteeism is a major threat to work productivity. Our objective was to assess the relationship between physical activity and unplanned illness-related absenteeism from work.We implemented physical activity program for sedentary non-clinician employees of a tertiary medical center. Financial rewards were available for reaching accelerometer-measured ambulatory physical activity goals over a 24-week period. We categorized participants into three groups based on mean levels of physical activity: low (0-74 min/week, medium (75-149 min/week and meeting CDC guidelines (≥150 min/week. We built a multivariable Poisson regression model to evaluate the relationship between physical activity and rates of unplanned illness-related absenteeism.The sample consisted of 292 employees who participated in the program. Their mean age was 38 years (SD 11, 83% were female, and 38% were obese. Over the 24 intervention weeks, participants engaged in a mean of 90 min/week (SD 74 of physical activity and missed a mean of 14 hours of work (SD 38 due to illness. Unplanned absenteeism due to illness was associated with physical activity. As compared to the group meeting CDC guidelines, in multivariable analyses those in the medium physical activity group had a 2.4 (95% CI 1.3-4.5 fold higher rate of illness-related absenteeism and those in the lowest physical activity group had a 3.5 (95% CI 1.7-7.2 fold higher rate of illness-related absenteeism.Less physical activity was associated with more illness-related absenteeism. Workforce-based interventions to increase physical activity may thus be a promising vehicle to reduce unplanned illness-related absenteeism.

  14. Physical activity and unplanned illness-related work absenteeism: Data from an employee wellness program

    Science.gov (United States)

    Yang, Heidi Y.; Katz, Jeffrey N.; Collins, Jamie E.

    2017-01-01

    Background Illness-related absenteeism is a major threat to work productivity. Our objective was to assess the relationship between physical activity and unplanned illness-related absenteeism from work. Methods We implemented physical activity program for sedentary non-clinician employees of a tertiary medical center. Financial rewards were available for reaching accelerometer-measured ambulatory physical activity goals over a 24-week period. We categorized participants into three groups based on mean levels of physical activity: low (0–74 min/week), medium (75–149 min/week) and meeting CDC guidelines (≥150 min/week). We built a multivariable Poisson regression model to evaluate the relationship between physical activity and rates of unplanned illness-related absenteeism. Results The sample consisted of 292 employees who participated in the program. Their mean age was 38 years (SD 11), 83% were female, and 38% were obese. Over the 24 intervention weeks, participants engaged in a mean of 90 min/week (SD 74) of physical activity and missed a mean of 14 hours of work (SD 38) due to illness. Unplanned absenteeism due to illness was associated with physical activity. As compared to the group meeting CDC guidelines, in multivariable analyses those in the medium physical activity group had a 2.4 (95% CI 1.3–4.5) fold higher rate of illness-related absenteeism and those in the lowest physical activity group had a 3.5 (95% CI 1.7–7.2) fold higher rate of illness-related absenteeism. Discussion Less physical activity was associated with more illness-related absenteeism. Workforce-based interventions to increase physical activity may thus be a promising vehicle to reduce unplanned illness-related absenteeism. PMID:28472084

  15. Online Activity Levels Are Related to Caffeine Dependency.

    Science.gov (United States)

    Phillips, James G; Landhuis, C Erik; Shepherd, Daniel; Ogeil, Rowan P

    2016-05-01

    Online activity could serve in the future as behavioral markers of emotional states for computer systems (i.e., affective computing). Hence, this study considered relationships between self-reported stimulant use and online study patterns. Sixty-two undergraduate psychology students estimated their daily caffeine use, and this was related to study patterns as tracked by their use of a Learning Management System (Blackboard). Caffeine dependency was associated with less time spent online, lower rates of file access, and fewer online activities completed. Reduced breadth or depth of processing during work/study could be used as a behavioral marker of stimulant use.

  16. Estimating relative demand for wildlife: Conservation activity indicators

    Science.gov (United States)

    Gray, Gary G.; Larson, Joseph S.

    1982-09-01

    An alternative method of estimating relative demand among nonconsumptive uses of wildlife and among wildlife species is proposed. A demand intensity score (DIS), derived from the relative extent of an individual's involvement in outdoor recreation and conservation activities, is used as a weighting device to adjust the importance of preference rankings for wildlife uses and wildlife species relative to other members of a survey population. These adjusted preference rankings were considered to reflect relative demand levels (RDLs) for wildlife uses and for species by the survey population. This technique may be useful where it is not possible or desirable to estimate demand using traditional economic means. In one of the findings from a survey of municipal conservation commission members in Massachusetts, presented as an illustration of this methodology, poisonous snakes were ranked third in preference among five groups of reptiles. The relative demand level for poisonous snakes, however, was last among the five groups.

  17. Physical activity is related to quality of life in older adults.

    Science.gov (United States)

    Acree, Luke S; Longfors, Jessica; Fjeldstad, Anette S; Fjeldstad, Cecilie; Schank, Bob; Nickel, Kevin J; Montgomery, Polly S; Gardner, Andrew W

    2006-06-30

    Physical activity is associated with health-related quality of life (HRQL) in clinical populations, but less is known whether this relationship exists in older men and women who are healthy. Thus, this study determined if physical activity was related to HRQL in apparently healthy, older subjects. Measures were obtained from 112 male and female volunteers (70 +/- 8 years, mean +/- SD) recruited from media advertisements and flyers around the Norman, Oklahoma area. Data was collected using a medical history questionnaire, HRQL from the Medical Outcomes Survey short form-36 questionnaire, and physical activity level from the Johnson Space Center physical activity scale. Subjects were separated into either a higher physically active group (n = 62) or a lower physically active group (n = 50) according to the physical activity scale. The HRQL scores in all eight domains were significantly higher (p social functioning (92 +/- 18 vs. 83 +/- 19, p = 0.040). General health, role-emotional, and mental health were not significantly different (p > 0.05) between the two groups. Healthy older adults who regularly participated in physical activity of at least moderate intensity for more than one hour per week had higher HRQL measures in both physical and mental domains than those who were less physically active. Therefore, incorporating more physical activity into the lifestyles of sedentary or slightly active older individuals may improve their HRQL.

  18. THE RADIO ACTIVITY-ROTATION RELATION OF ULTRACOOL DWARFS

    International Nuclear Information System (INIS)

    McLean, M.; Berger, E.; Reiners, A.

    2012-01-01

    We present a new radio survey of about 100 late-M and L dwarfs undertaken with the Very Large Array. The sample was chosen to explore the role of rotation in the radio activity of ultracool dwarfs. As part of the survey we discovered radio emission from three new objects, 2MASS J 0518113 – 310153 (M6.5), 2MASS J 0952219 – 192431 (M7), and 2MASS J 1314203 + 132001 (M7), and made an additional detection of LP 349-25 (M8). Combining the new sample with results from our previous studies and from the literature, we compile the largest sample to date of ultracool dwarfs with radio observations and measured rotation velocities (167 objects). In the spectral type range M0-M6 we find a radio activity-rotation relation, with saturation at L rad /L bol ≈ 10 –7.5 above vsin i ≈ 5 km s –1 , similar to the relation in Hα and X-rays. However, at spectral types ∼> M7 the ratio of radio to bolometric luminosity increases significantly regardless of rotation velocity, and the scatter in radio luminosity increases. In particular, while the most rapid rotators (vsin i ∼> 20 km s –1 ) exhibit 'super-saturation' in X-rays and Hα, this effect is not seen in the radio. We also find that ultracool dwarfs with vsin i ∼> 20 km s –1 have a higher radio detection fraction by about a factor of three compared to objects with vsin i ∼ –1 . When measured in terms of the Rossby number (Ro), the radio activity-rotation relation follows a single trend and with no apparent saturation from G to L dwarfs and down to Ro ∼ 10 –3 ; in X-rays and Hα there is clear saturation at Ro ∼ rad /R 2 * ) as a function of Ro. The continued role of rotation in the overall level of radio activity and in the fraction of active sources, and the single trend of L rad /L bol and L rad /R 2 * as a function of Ro from G to L dwarfs, indicates that rotation effects are important in regulating the topology or strength of magnetic fields in at least some fully convective dwarfs. The fact that

  19. Costs in Relation to Disability, Disease Activity, and Health-related Quality of Life in Rheumatoid Arthritis

    DEFF Research Database (Denmark)

    Wallman, Johan K; Eriksson, Jonas K; Nilsson, Jan-Åke

    2016-01-01

    between-patient associations) and by generalized estimating equations (GEE), using all observations to also account for within-patient associations of HAQ/DAS28/EQ-5D to costs. RESULTS: Regardless of the methodology (linear or GEE regression), HAQ was most closely related to both cost types, while work......OBJECTIVE: To compare how costs relate to disability, disease activity, and health-related quality of life (HRQOL) in rheumatoid arthritis (RA). METHODS: Antitumor necrosis factor (anti-TNF)-treated patients with RA in southern Sweden (n = 2341) were monitored 2005-2010. Health Assessment...... Questionnaire (HAQ), 28-joint Disease Activity Score (DAS28), and EQ-5D scores were linked to register-derived costs of antirheumatic drugs (excluding anti-TNF agents), patient care, and work loss from 30 days before to 30 days after each visit (n = 13,289). Associations of HAQ/DAS28/EQ-5D to healthcare...

  20. Cross-language activation of morphological relatives in cognates: the role of orthographic overlap and task-related processing

    Science.gov (United States)

    Mulder, Kimberley; Dijkstra, Ton; Baayen, R. Harald

    2015-01-01

    We considered the role of orthography and task-related processing mechanisms in the activation of morphologically related complex words during bilingual word processing. So far, it has only been shown that such morphologically related words (i.e., morphological family members) are activated through the semantic and morphological overlap they share with the target word. In this study, we investigated family size effects in Dutch-English identical cognates (e.g., tent in both languages), non-identical cognates (e.g., pil and pill, in English and Dutch, respectively), and non-cognates (e.g., chicken in English). Because of their cross-linguistic overlap in orthography, reading a cognate can result in activation of family members both languages. Cognates are therefore well-suited for studying mechanisms underlying bilingual activation of morphologically complex words. We investigated family size effects in an English lexical decision task and a Dutch-English language decision task, both performed by Dutch-English bilinguals. English lexical decision showed a facilitatory effect of English and Dutch family size on the processing of English-Dutch cognates relative to English non-cognates. These family size effects were not dependent on cognate type. In contrast, for language decision, in which a bilingual context is created, Dutch and English family size effects were inhibitory. Here, the combined family size of both languages turned out to better predict reaction time than the separate family size in Dutch or English. Moreover, the combined family size interacted with cognate type: the response to identical cognates was slowed by morphological family members in both languages. We conclude that (1) family size effects are sensitive to the task performed on the lexical items, and (2) depend on both semantic and formal aspects of bilingual word processing. We discuss various mechanisms that can explain the observed family size effects in a spreading activation framework

  1. Cross-language activation of morphological relatives in cognates: The role of orthographic overlap and task-related processing

    Directory of Open Access Journals (Sweden)

    Kimberley eMulder

    2015-02-01

    Full Text Available We considered the role of orthography and task-related processing mechanisms in the activation of morphologically related complex words during bilingual word processing. So far, it has only been shown that such morphologically related words (i.e., morphological family members are activated through the semantic and morphological overlap they share with the target word. In this study, we investigated family size effects in Dutch-English identical cognates (e.g., tent in both languages, non-identical cognates (e.g., pil and pill, in English and Dutch, respectively, and non-cognates (e.g., chicken in English. Because of their cross-linguistic overlap in orthography, reading a cognate can result in activation of family members both languages. Cognates are therefore well-suited for studying mechanisms underlying bilingual activation of morphologically complex words. We investigated family size effects in an English lexical decision task and a Dutch-English language decision task, both performed by Dutch-English bilinguals. English lexical decision showed a facilitatory effect of English and Dutch family size on the processing of English-Dutch cognates relative to English non-cognates. These family size effects were not dependent on cognate type. In contrast, for language decision, in which a bilingual context is created, Dutch and English family size effects were inhibitory. Here, the combined family size of both languages turned out to better predict reaction time than the separate family size in Dutch or English. Moreover, the combined family size interacted with cognate type: The response to identical cognates was slowed by morphological family members in both languages. We conclude that (1 family size effects are sensitive to the task performed on the lexical items, and (2 depend on both semantic and formal aspects of bilingual word processing. We discuss various mechanisms that can explain the observed family size effects in a spreading

  2. Automatic activation of categorical and abstract analogical relations in analogical reasoning.

    Science.gov (United States)

    Green, Adam E; Fugelsang, Jonathan A; Dunbar, Kevin N

    2006-10-01

    We examined activation of concepts during analogical reasoning. Subjects made either analogical judgments or categorical judgments about four-word sets. After each four-word set, they named the ink color of a single word in a modified Stroop task. Words that referred to category relations were primed (as indicated by longer response times on Stroop color naming) subsequent to analogical judgments and categorical judgments. This finding suggests that activation of category concepts plays a fundamental role in analogical thinking. When colored words referred to analogical relations, priming occurred subsequent to analogical judgments, but not to categorical judgments, even though identical four-word stimuli were used for both types of judgments. This finding lends empirical support to the hypothesis that, when people comprehend the analogy between two items, they activate an abstract analogical relation that is distinct from the specific content items that compose the analogy.

  3. Understanding the relationship between student attitudes and student learning

    Science.gov (United States)

    Cahill, Michael J.; McDaniel, Mark A.; Frey, Regina F.; Hynes, K. Mairin; Repice, Michelle; Zhao, Jiuqing; Trousil, Rebecca

    2018-02-01

    Student attitudes, defined as the extent to which one holds expertlike beliefs about and approaches to physics, are a major research topic in physics education research. An implicit but rarely tested assumption underlying much of this research is that student attitudes play a significant part in student learning and performance. The current study directly tested this attitude-learning link by measuring the association between incoming attitudes (Colorado Learning Attitudes about Science Survey) and student learning during the semester after statistically controlling for the effects of prior knowledge [early-semester Force Concept Inventory (FCI) or Brief Electricity and Magnetism Assessment (BEMA)]. This study spanned four different courses and included two complementary measures of student knowledge: late-semester concept inventory scores (FCI or BEMA) and exam averages. In three of the four courses, after controlling for prior knowledge, attitudes significantly predicted both late-semester concept inventory scores and exam averages, but in all cases these attitudes explained only a small amount of variance in concept-inventory and exam scores. Results indicate that after accounting for students' incoming knowledge, attitudes may uniquely but modestly relate to how much students learn and how well they perform in the course.

  4. Diverse Expected Gradient Active Learning for Relative Attributes.

    Science.gov (United States)

    You, Xinge; Wang, Ruxin; Tao, Dacheng

    2014-06-02

    The use of relative attributes for semantic understanding of images and videos is a promising way to improve communication between humans and machines. However, it is extremely labor- and time-consuming to define multiple attributes for each instance in large amount of data. One option is to incorporate active learning, so that the informative samples can be actively discovered and then labeled. However, most existing active-learning methods select samples one at a time (serial mode), and may therefore lose efficiency when learning multiple attributes. In this paper, we propose a batch-mode active-learning method, called Diverse Expected Gradient Active Learning (DEGAL). This method integrates an informativeness analysis and a diversity analysis to form a diverse batch of queries. Specifically, the informativeness analysis employs the expected pairwise gradient length as a measure of informativeness, while the diversity analysis forces a constraint on the proposed diverse gradient angle. Since simultaneous optimization of these two parts is intractable, we utilize a two-step procedure to obtain the diverse batch of queries. A heuristic method is also introduced to suppress imbalanced multi-class distributions. Empirical evaluations of three different databases demonstrate the effectiveness and efficiency of the proposed approach.

  5. 12 CFR 225.131 - Activities closely related to banking.

    Science.gov (United States)

    2010-01-01

    ...; operation and management of a trust department; international banking; foreign exchange transactions... specialized lending provisions; marketing operations, including research, market development and advertising... Holding Companies Interpretations § 225.131 Activities closely related to banking. (a) Bank management...

  6. Measuring emotions during epistemic activities: the Epistemically-Related Emotion Scales.

    Science.gov (United States)

    Pekrun, Reinhard; Vogl, Elisabeth; Muis, Krista R; Sinatra, Gale M

    2017-09-01

    Measurement instruments assessing multiple emotions during epistemic activities are largely lacking. We describe the construction and validation of the Epistemically-Related Emotion Scales, which measure surprise, curiosity, enjoyment, confusion, anxiety, frustration, and boredom occurring during epistemic cognitive activities. The instrument was tested in a multinational study of emotions during learning from conflicting texts (N = 438 university students from the United States, Canada, and Germany). The findings document the reliability, internal validity, and external validity of the instrument. A seven-factor model best fit the data, suggesting that epistemically-related emotions should be conceptualised in terms of discrete emotion categories, and the scales showed metric invariance across the North American and German samples. Furthermore, emotion scores changed over time as a function of conflicting task information and related significantly to perceived task value and use of cognitive and metacognitive learning strategies.

  7. [Occupation-, transportation- and leisure-related physical activity: gender inequalities in Santander, Colombia].

    Science.gov (United States)

    Hormiga-Sánchez, Claudia M; Alzate-Posada, Martha L; Borrell, Carme; Palència, Laia; Rodríguez-Villamizar, Laura A; Otero-Wandurraga, Johanna A

    2016-04-01

    Objectives To estimate the prevalence of occupation-, transportation- and leisure-related physical activity, its compliance with recommendations, and to explore its association with demographic and socioeconomic variables in men and women of the Department of Santander (Colombia). Methods The sample consisted of 2421 people between 15 and 64 years of age, participants in the Risk Factors for Chronic Diseases of Santander cross-sectional study, developed in 2010. The Global Physical Activity Questionnaire was used for data collection. Age-adjusted prevalence ratios were calculated and multivariate analysis models were built by sex using robust Poisson regression. Results The prevalence of occupational and leisure physical activity and compliance with recommendations were lower in women. Sexual division of labor and a low socioeconomic level negatively influenced physical activity in women, limiting the possibility of practice of those principally engaged in unpaid work at home. Young or single men and those living in higher socioeconomic areas were more likely to practice physical activity in leisure time and meet recommendations. Conclusion Physical activity surveillance and related public policies should take into account the inequalities between the practice of men and women related to their socioeconomic conditions and the sexual division of labor.

  8. 2017 Military Services Gender Relations Focus Groups: Active Duty

    Science.gov (United States)

    2018-04-30

    Office of People Analytics Office of People Analytics (OPA) Defense Research, Surveys, and Statistics Center 4800 Mark Center Drive, Suite 06E22...Relations (2017 MSGR) Focus Groups among active duty members. This is the third6 administration of gender relations focus groups. This introductory ...Enlisted, Male “It is true statistically , a majority of sexual assaults there is alcohol or drugs. In the military, it’s into the alcohol more than

  9. Summary of activities on CSS related issues

    International Nuclear Information System (INIS)

    Loriaux, E.

    1996-01-01

    In the Netherlands there are two nuclear power plants. One 60Mw BWR for research purposes in Dodewaard, and one PWR 450 Mw IN Borssele. Both of these NPPs are undergoing an extensive upgrading. These plants use several CSS-like systems. These systems are primarily aimed to support and monitor safe and correct operation of the process or to detect specific (e.g. mechanical) problems in an early stage. The NPP in Dodewaard is upgrading its training simulator and process presentation system (''Datalogger''). The activities related to the CRP are mainly within the framework of the Dodewaard plant. This final national report will give an overview of these activities with particular emphasis on the replacement of the Datalogger system. Some additional information is given on trends in CSSs as used in fossil power plants. (author). 2 figs

  10. Quantitative Structure-Activity Relationships and Docking Studies of Calcitonin Gene-Related Peptide Antagonists

    DEFF Research Database (Denmark)

    Jenssen, Håvard; Mehrabian, Mohadeseh; Kyani, Anahita

    2012-01-01

    Defining the role of calcitonin gene-related peptide in migraine pathogenesis could lead to the application of calcitonin gene-related peptide antagonists as novel migraine therapeutics. In this work, quantitative structure-activity relationship modeling of biological activities of a large range...... of calcitonin gene-related peptide antagonists was performed using a panel of physicochemical descriptors. The computational studies evaluated different variable selection techniques and demonstrated shuffling stepwise multiple linear regression to be superior over genetic algorithm-multiple linear regression....... The linear quantitative structure-activity relationship model revealed better statistical parameters of cross-validation in comparison with the non-linear support vector regression technique. Implementing only five peptide descriptors into this linear quantitative structure-activity relationship model...

  11. Consumer Health-Related Activities on Social Media: Exploratory Study.

    Science.gov (United States)

    Benetoli, Arcelio; Chen, Timothy F; Aslani, Parisa

    2017-10-13

    Although a number of studies have investigated how consumers use social media for health-related purposes, there is a paucity of studies in the Australian context. This study aimed to explore how Australian consumers used social media for health-related purposes, specifically how they identified social media platforms, which were used, and which health-related activities commonly took place. A total of 5 focus groups (n=36 participants), each lasting 60 to 90 minutes, were conducted in the Sydney metropolitan area. The group discussions were audiorecorded and transcribed verbatim. The transcripts were coded line-by-line and thematically analyzed. Participants used general search engines to locate health-related social media platforms. They accessed a wide range of social media on a daily basis, using several electronic devices (in particular, mobile phones). Although privacy was a concern, it did not prevent consumers from fully engaging in social media for health-related purposes. Blogs were used to learn from other people's experiences with the same condition. Facebook allowed consumers to follow health-related pages and to participate in disease-specific group discussions. Wikipedia was used for factual information about diseases and treatments. YouTube was accessed to learn about medical procedures such as surgery. No participant reported editing or contributing to Wikipedia or posting YouTube videos related to health topics. Twitter was rarely used for health-related purposes. Social media allowed consumers to obtain and provide disease and treatment-related information and social and emotional support for those living with the same condition. Most considered their participation as observational, but some also contributed (eg, responded to people's questions). Participants used a wide range of social media for health-related purposes. Medical information exchange (eg, disease and treatment) and social and emotional support were the cornerstones of their online

  12. Organized Activity Participation and Relational Aggression: The Role of Positive Youth Development.

    Science.gov (United States)

    Eisman, Andria B; Stoddard, Sarah A; Bauermeister, José A; Caldwell, Cleopatra H; Zimmerman, Marc A

    2018-02-01

    Relational aggression among early adolescents is a pervasive problem that negatively influences the health and well-being of youth. Strength-based approaches such as positive youth development (PYD) are a promising way to reduce risk of detrimental outcomes such as relational aggression. Participation in organized activities is a key way that youth build assets related to PYD. Yet, few researchers have examined empirically assets related to PYD as a mechanism by which organized activity participation may help reduce risk of relational aggression. In this study, we used structural equation modeling to investigate if assets associated with PYD mediate the relationship between organized activity participation and relational aggression using survey data from a diverse, school-based sample of early adolescents (N = 196; mean age = 12.39 years; SD = 0.52; 60% female; 45% African American, 27% White, 21% multiracial, and 7% other, 71% economically disadvantaged). We tested 2 competing models, 1 with decomposed PYD factors and 1 with an integrated PYD factor. Our results suggest that PYD better fit as an integrated versus decomposed construct, providing support for the notion that youth benefit most from assets related to PYD when they operate collectively. Our results also provide support for PYD-related factors as a mechanism by which participation may reduce risk of relational aggression. Limitations of this study, and implications for prevention are discussed.

  13. Regulatory behavior and frontal activity: Considering the role of revised-BIS in relative right frontal asymmetry.

    Science.gov (United States)

    Gable, Philip A; Neal, Lauren B; Threadgill, A Hunter

    2018-01-01

    Essential to human behavior are three core personality systems: approach, avoidance, and a regulatory system governing the two motivational systems. Decades of research has linked approach motivation with greater relative left frontal-cortical asymmetry. Other research has linked avoidance motivation with greater relative right frontal-cortical asymmetry. However, past work linking withdrawal motivation with greater relative right frontal asymmetry has been mixed. The current article reviews evidence suggesting that activation of the regulatory system (revised Behavioral Inhibition System [r-BIS]) may be more strongly related to greater relative right frontal asymmetry than withdrawal motivation. Specifically, research suggests that greater activation of the r-BIS is associated with greater relative right frontal activity, and reduced r-BIS activation is associated with reduced right frontal activity (greater relative left frontal activity). We review evidence examining trait and state frontal activity using EEG, source localization, lesion studies, neuronal stimulation, and fMRI supporting the idea that r-BIS may be the core personality system related to greater relative right frontal activity. In addition, the current review seeks to disentangle avoidance motivation and r-BIS as substrates of relative right frontal asymmetry. © 2017 Society for Psychophysiological Research.

  14. [Mammals' camera-trapping in Sierra Nanchititla, Mexico: relative abundance and activity patterns].

    Science.gov (United States)

    Monroy-Vilchis, Octavio; Zarco-González, Martha M; Rodríguez-Soto, Clarita; Soria-Díaz, Leroy; Urios, Vicente

    2011-03-01

    Species conservation and their management depend on the availability of their population behavior and changes in time. This way, population studies include aspects such as species abundance and activity pattern, among others, with the advantage that nowadays new technologies can be applied, in addition to common methods. In this study, we used camera-traps to obtain the index of relative abundance and to establish activity pattern of medium and large mammals in Sierra Nanchititla, Mexico. The study was conducted from December 2003 to May 2006, with a total sampling effort of 4 305 trap-days. We obtained 897 photographs of 19 different species. Nasua narica, Sylvilagus floridanus and Urocyon cinereoargenteus were the most abundant, in agreement with the relative abundance index (RAI, number of independent records/100 trap-days), and according to previous studies with indirect methods in the area. The activity patterns of the species showed that 67% of them are nocturnal, except Odocoileus virginianus, Nasua narica and others. Some species showed differences with previously reported patterns, which are related with seasonality, resources availability, organism sex, principally. The applied method contributed with reliable data about relative abundance and activity patterns.

  15. 'Low-activation' fusion materials development and related nuclear data needs

    International Nuclear Information System (INIS)

    Cierjacks, S.

    1990-01-01

    So-called ''low-activation'' materials are presently considered as an important means of improving the safety characteristics of future DT fusion reactors. Essential benefits are expected in various problem areas ranging from operation considerations to aspects of decommissioning and waste disposal. Present programs on ''low-activation'' materials development depend strongly on reliable activity calculations for a wide range of technologically important materials. The related nuclear data requirements and important needs for more and improved nuclear data are discussed. (author). 32 refs, 4 figs, 4 tabs

  16. Relative humidity and activity patterns of Ixodes scapularis (Acari: Ixodidae)

    Science.gov (United States)

    Berger, K.A.; Ginsberg, Howard S.; Gonzalez, L.; Mather, T.N.

    2014-01-01

    Laboratory studies have shown clear relationships between relative humidity (RH) and the activity and survival of Ixodes scapularis Say (blacklegged tick). However, field studies have produced conflicting results. We examined this relationship using weekly tick count totals and hourly RH observations at three field sites, stratified by latitude, within the state of Rhode Island. Records of nymphal tick abundance were compared with several RH-related variables (e.g., RH at time of sampling and mean weekly daytime RH). In total, 825 nymphs were sampled in 2009, a year of greater precipitation, with a weighted average leaf litter RH recorded at time of sampling of 85.22%. Alternatively, 649 nymphs were collected in 2010, a year of relatively low precipitation, and a weighted average RH recorded at time of sampling was 75.51%. Negative binomial regression analysis of tick count totals identified cumulative hours <82% RH threshold as a significant factor observed in both years (2009: P = 0.0037; 2010: P < 0.0001). Mean weekly daytime RH did not significantly predict tick activity in either year. However, mean weekly daytime RH recorded with 1-wk lag before sample date was a significant variable (P = 0.0016) in 2010. These results suggest a lag effect between moisture availability and patterns of tick activity and abundance. Differences in the relative importance of each RH variable between years may have been due to abnormally wet summer conditions in 2009.

  17. Relation of Biospeckle Activity with Quality Attributes of Apples

    Directory of Open Access Journals (Sweden)

    Artur Zdunek

    2011-06-01

    Full Text Available Biospeckle is nondestructive optical technique based on the analysis of variations of laser light scattered from biological samples. Biospeckle activity reflects the state of the investigated object. In this study the relation of biospeckle activity (BA with firmness, soluble solids content (SSC, titratable acidity (TA and starch content (SC during the shelf life of seven apple cultivars was studied. The results showed that the quality attributes change significantly during storage. Significant and pronounced positive correlation between BA and SC was found. This result shows that degradation of starch granules, which could be stimulated to vibration by intracellular cyclosis, causes a lesser number of laser light scattering centers and results in smaller apparent biospeckle activity.

  18. Relation of biospeckle activity with quality attributes of apples.

    Science.gov (United States)

    Zdunek, Artur; Cybulska, Justyna

    2011-01-01

    Biospeckle is nondestructive optical technique based on the analysis of variations of laser light scattered from biological samples. Biospeckle activity reflects the state of the investigated object. In this study the relation of biospeckle activity (BA) with firmness, soluble solids content (SSC), titratable acidity (TA) and starch content (SC) during the shelf life of seven apple cultivars was studied. The results showed that the quality attributes change significantly during storage. Significant and pronounced positive correlation between BA and SC was found. This result shows that degradation of starch granules, which could be stimulated to vibration by intracellular cyclosis, causes a lesser number of laser light scattering centers and results in smaller apparent biospeckle activity.

  19. Objectively measured daily physical activity related to aerobic fitness in young children

    DEFF Research Database (Denmark)

    Dencker, Magnus; Bugge, Anna; Hermansen, Bianca

    2010-01-01

    The purpose of this study was to investigate by direct measurement the cross-sectional relationship between accelerometer-measured physical activity and peak oxygen uptake (VO(2peak): ml x min(-1) x kg(-1)), in a population-based cohort of young children, since such data are scarce. The study...... analyses indicated that the various physical activity variables explained between 2 and 8% of the variance in VO(2peak) in boys. In this population-based cohort, most daily activity variables were positively related to aerobic fitness in boys, whereas less clear relationships were observed in girls. Our...... finding that physical activity was only uniformly related to aerobic fitness in boys partly contradicts previous studies in older children and adolescents....

  20. Simulation of isothermal multi-phase fuel-coolant interaction using MPS method with GPU acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Gou, W.; Zhang, S.; Zheng, Y. [Zhejiang Univ., Hangzhou (China). Center for Engineering and Scientific Computation

    2016-07-15

    The energetic fuel-coolant interaction (FCI) has been one of the primary safety concerns in nuclear power plants. Graphical processing unit (GPU) implementation of the moving particle semi-implicit (MPS) method is presented and used to simulate the fuel coolant interaction problem. The governing equations are discretized with the particle interaction model of MPS. Detailed implementation on single-GPU is introduced. The three-dimensional broken dam is simulated to verify the developed GPU acceleration MPS method. The proposed GPU acceleration algorithm and developed code are then used to simulate the FCI problem. As a summary of results, the developed GPU-MPS method showed a good agreement with the experimental observation and theoretical prediction.

  1. Physical activity attenuates age-related biomarker alterations in preclinical AD.

    Science.gov (United States)

    Okonkwo, Ozioma C; Schultz, Stephanie A; Oh, Jennifer M; Larson, Jordan; Edwards, Dorothy; Cook, Dane; Koscik, Rebecca; Gallagher, Catherine L; Dowling, N M; Carlsson, Cynthia M; Bendlin, Barbara B; LaRue, Asenath; Rowley, Howard A; Christian, Brad T; Asthana, Sanjay; Hermann, Bruce P; Johnson, Sterling C; Sager, Mark A

    2014-11-04

    To examine whether engagement in physical activity might favorably alter the age-dependent evolution of Alzheimer disease (AD)-related brain and cognitive changes in a cohort of at-risk, late-middle-aged adults. Three hundred seventeen enrollees in the Wisconsin Registry for Alzheimer's Prevention underwent T1 MRI; a subset also underwent (11)C-Pittsburgh compound B-PET (n = 186) and (18)F-fluorodeoxyglucose-PET (n = 152) imaging. Participants' responses on a self-report measure of current physical activity were used to classify them as either physically active or physically inactive based on American Heart Association guidelines. They also completed a comprehensive neuropsychological battery. Covariate-adjusted regression analyses were used to test whether the adverse effect of age on imaging and cognitive biomarkers was modified by physical activity. There were significant age × physical activity interactions for β-amyloid burden (p = 0.014), glucose metabolism (p = 0.015), and hippocampal volume (p = 0.025) such that, with advancing age, physically active individuals exhibited a lesser degree of biomarker alterations compared with the physically inactive. Similar age × physical activity interactions were also observed on cognitive domains of Immediate Memory (p = 0.042) and Visuospatial Ability (p = 0.016). In addition, the physically active group had higher scores on Speed and Flexibility (p = 0.002) compared with the inactive group. In a middle-aged, at-risk cohort, a physically active lifestyle is associated with an attenuation of the deleterious influence of age on key biomarkers of AD pathophysiology. However, because our observational, cross-sectional design cannot establish causality, randomized controlled trials/longitudinal studies will be necessary for determining whether midlife participation in structured physical exercise forestalls the development of AD and related disorders in later life. © 2014 American Academy of Neurology.

  2. Imaging movement-related activity in medicated Parkin-associated and sporadic Parkinson's disease

    DEFF Research Database (Denmark)

    van Eimeren, Thilo; Binkofski, Ferdinand; Buhmann, Carsten

    2010-01-01

    Treatment-related motor complications such as dyskinesias are a major problem in the long-term management of Parkinson's disease (PD). In sporadic PD, a relatively early onset of the disease is known to be associated with an early development of dyskinesias. Although linked with early onset...... selected movements. Patients with Parkin-associated and sporadic PD showed no difference in movement-related activation patterns. Moreover, the covariates 'age' and 'disease duration' similarly influenced brain activation in both patient groups. The present finding suggests that a stable long-term motor...

  3. A systematic review of financial incentives for physical activity: The effects on physical activity and related outcomes

    NARCIS (Netherlands)

    Barte, J.C.M.; Wendel-Vos, G.C.W.

    2017-01-01

    The aim of this review is to give an overview of the available evidence on the effects of financial incentives to stimulate physical activity. Therefore, a systematic literature search was performed for randomized trials that investigate the effects of physical-activity-related financial incentives

  4. Everyday science & science every day: Science-related talk & activities across settings

    Science.gov (United States)

    Zimmerman, Heather

    To understand the development of science-related thinking, acting, and learning in middle childhood, I studied youth in schools, homes, and other neighborhood settings over a three-year period. The research goal was to analyze how multiple everyday experiences influence children's participation in science-related practices and their thinking about science and scientists. Ethnographic and interaction analysis methodologies were to study the cognition and social interactions of the children as they participated in activities with peers, family, and teachers (n=128). Interviews and participant self-documentation protocols elucidated the participants' understandings of science. An Everyday Expertise (Bell et al., 2006) theoretical framework was employed to study the development of science understandings on three analytical planes: individual learner, social groups, and societal/community resources. Findings came from a cross-case analysis of urban science learners and from two within-case analyses of girls' science-related practices as they transitioned from elementary to middle school. Results included: (1) children participated actively in science across settings---including in their homes as well as in schools, (2) children's interests in science were not always aligned to the school science content, pedagogy, or school structures for participation, yet children found ways to engage with science despite these differences through crafting multiple pathways into science, (3) urban parents were active supporters of STEM-related learning environments through brokering access to social and material resources, (4) the youth often found science in their daily activities that formal education did not make use of, and (5) children's involvement with science-related practices can be developed into design principles to reach youth in culturally relevant ways.

  5. THE EDUCATIONAL POTENTIAL OF FATHERHOOD: CONCEPTUAL BASES OF RESEARCH AND SUPPORT

    Directory of Open Access Journals (Sweden)

    V. I. Zagvyazinsky

    2017-01-01

    interpreted.The concept “language” of the father-child interaction (FCI, new to psychology and pedagogical knowledge, is introduced. Given the above concept consists in the direct emotional and communicative interaction based on empathy and “episodic” relation of a father to a child's life, i.e. pragmatic love.The general logic of FCI can be presented as “language-form-value”; particular options of implementation of the general formula can be “sport-training-health”, “literature-reading-meaning”, “arts-concerts-tastes”, etc. According to the authors, practical application of concrete substantial forms-units (“languages” of the FCI system is an effective pedagogical tool for individual and personal updating of fatherhood in order to positively influence the formation of a child’s socialization.The concept of educational potential of fatherhood which includes three key determinants is worked out: knowledge and erudition of a father-parent; his personal qualities; system of motives and values.Practical significance. The proposed three-part model of determinants for educational potential of fatherhood could be applied to undertake the diagnostics of this potential among parents for organization of their pedagogical support. The idea of “languages” of FCI might be useful for social projects implementation to support families and institute of fatherhood.

  6. Intensity, but not duration, of physical activities is related to cognitive function

    NARCIS (Netherlands)

    Angevaren, Maaike; Vanhees, Luc; Wendel-Vos, Wanda; Verhaar, Harald J. J.; Aufdernkarnpe, Geert; Aleman, Andrie; Verschuren, W. M. Monique

    2007-01-01

    Background Physical activity is thought to facilitate cognitive performance and to slow down the rate of age-related cognitive decline. This study aimed to investigate the association between the time spent on physical activity as well as the average intensity of these activities and cognitive

  7. Intensity, but not duration of physical activities is related to cognitive function.

    NARCIS (Netherlands)

    A. Aleman; Geert Aufdemkampe; H.J. Verhaar; W. Wendel-Vos; Drs. Maaike Angevaren; Prof. Dr. Luc L.E.M.J. Vanhees; W.M. Verschuren

    2007-01-01

    Background: Physical activity is thought to facilitate cognitive performance and to slow down the rate of age-related cognitive decline. This study aimed to investigate the association between the time spent on physical activity as well as the average intensity of these activities and cognitive

  8. Dispersion relations and sum rules for natural optical activity

    International Nuclear Information System (INIS)

    Thomaz, M.T.; Nussenzveig, H.M.

    1981-06-01

    Dispersion relations and sum rules are derived for the complex rotatory power of an arbitrary linear (nonmagnetic) isotropic medium showing natural optical activity. Both previously known dispersion relations and sum rules as well as new ones are obtained. It is shown that the Rosenfeld-Condon dispersion formula is inconsistent with the expected asymptotic behavior at high frequencies. A new dispersion formula based on quantum eletro-dynamics removes this inconsistency; however, it still requires modification in the low-frequency limit. (Author) [pt

  9. Fuel performance improvement program. Quarterly/annual progress report, October 1977--September 1978

    International Nuclear Information System (INIS)

    Crouthamel, C.E.

    1978-10-01

    This quarterly/annual report reviews and summarizes the activities performed in support of the Fuel Performance Improvement Program (FPIP) during Fiscal Year 1978 with emphasis on those activities that transpired during the quarter ending September 30, 1978. Significant progress has been made in achieving the primary objectives of the program, i.e., to demonstrate commercially viable fuel concepts with improved fuel - cladding interaction (FCI) behavior. This includes out-of-reactor experiments to support the fuel concepts being evaluated, initiation of instrumented test rod experiments in the Halden Boiling Water Reactor (HBWR), and fabrication of the first series of demonstration rods for irradiation in the Big Rock Point Reactor

  10. Performance of different colour quality metrics proposed to CIE TC 1-91

    OpenAIRE

    Bhusal, Pramod; Dangol, Rajendra

    2017-01-01

    The main aim of the article is to find out the performance of different metrics proposed to CIE TC 1-91. Currently, six different indexes have been proposed to CIE TC 1-91: Colour Quality Scale (CQS), Feeling of Contrast Index (FCI), Memory colour rendering index (MCRI), Preference of skin (PS), Relative gamut area index (RGAI) and Illuminating Engineering society Method for evaluating light source colour rendition (IES TM-30). The evaluation and analysis are based on previously conducted exp...

  11. Fetal Intervention in Right Outflow Tract Obstructive Disease: Selection of Candidates and Results

    Science.gov (United States)

    Gómez Montes, E.; Herraiz, I.; Mendoza, A.; Galindo, A.

    2012-01-01

    Objectives. To describe the process of selection of candidates for fetal cardiac intervention (FCI) in fetuses diagnosed with pulmonary atresia-critical stenosis with intact ventricular septum (PA/CS-IVS) and report our own experience with FCI for such disease. Methods. We searched our database for cases of PA/CS-IVS prenatally diagnosed in 2003–2012. Data of 38 fetuses were retrieved and analyzed. FCI were offered to 6 patients (2 refused). In the remaining it was not offered due to the presence of either favourable prognostic echocardiographic markers (n = 20) or poor prognostic indicators (n = 12). Results. The outcome of fetuses with PA/CS-IVS was accurately predicted with multiparametric scoring systems. Pulmonary valvuloplasty was technically successful in all 4 fetuses. The growth of the fetal right heart and hemodynamic parameters showed a Gaussian-like behaviour with an improvement in the first weeks and slow worsening as pregnancy advanced, probably indicating a restenosis. Conclusions. The most likely type of circulation after birth may be predicted in the second trimester of pregnancy by means of combining cardiac dimensions and functional parameters. Fetal pulmonary valvuloplasty in midgestation is technically feasible and in well-selected cases may improve right heart growth, fetal hemodynamics, and postnatal outcome. PMID:22928144

  12. The effects of students' reasoning abilities on conceptual understandings and problem-solving skills in introductory mechanics

    International Nuclear Information System (INIS)

    Ates, S; Cataloglu, E

    2007-01-01

    The purpose of this study was to determine if there are relationships among freshmen/first year students' reasoning abilities, conceptual understandings and problem-solving skills in introductory mechanics. The sample consisted of 165 freshmen science education prospective teachers (female = 86, male = 79; age range 17-21) who were enrolled in an introductory physics course. Data collection was done during the fall semesters in two successive years. At the beginning of each semester, the force concept inventory (FCI) and the classroom test of scientific reasoning (CTSR) were administered to assess students' initial understanding of basic concepts in mechanics and reasoning levels. After completing the course, the FCI and the mechanics baseline test (MBT) were administered. The results indicated that there was a significant difference in problem-solving skill test mean scores, as measured by the MBT, among concrete, formal and postformal reasoners. There were no significant differences in conceptual understanding levels of pre- and post-test mean scores, as measured by FCI, among the groups. The Benferroni post hoc comparison test revealed which set of reasoning levels showed significant difference for the MBT scores. No statistical difference between formal and postformal reasoners' mean scores was observed, while the mean scores between concrete and formal reasoners and concrete and postformal reasoners were statistically significantly different

  13. Can dual processing theory explain physics students’ performance on the Force Concept Inventory?

    Directory of Open Access Journals (Sweden)

    Anna K. Wood

    2016-07-01

    Full Text Available According to dual processing theory there are two types, or modes, of thinking: system 1, which involves intuitive and nonreflective thinking, and system 2, which is more deliberate and requires conscious effort and thought. The Cognitive Reflection Test (CRT is a widely used and robust three item instrument that measures the tendency to override system 1 thinking and to engage in reflective, system 2 thinking. Each item on the CRT has an intuitive (but wrong answer that must be rejected in order to answer the item correctly. We therefore hypothesized that performance on the CRT may give useful insights into the cognitive processes involved in learning physics, where success involves rejecting the common, intuitive ideas about the world (often called misconceptions and instead carefully applying physical concepts. This paper presents initial results from an ongoing study examining the relationship between students’ CRT scores and their performance on the Force Concept Inventory (FCI, which tests students’ understanding of Newtonian mechanics. We find that a higher CRT score predicts a higher FCI score for both precourse and postcourse tests. However, we also find that the FCI normalized gain is independent of CRT score. The implications of these results are discussed.

  14. Fear conditioning-related changes in cerebellar Purkinje cell activities in goldfish

    Directory of Open Access Journals (Sweden)

    Yoshida Masayuki

    2012-10-01

    Full Text Available Abstract Background Fear conditioning-induced changes in cerebellar Purkinje cell responses to a conditioned stimulus have been reported in rabbits. It has been suggested that synaptic long-term potentiation and the resulting increases in firing rates of Purkinje cells are related to the acquisition of conditioned fear in mammals. However, Purkinje cell activities during acquisition of conditioned fear have not been analysed, and changes in Purkinje cell activities throughout the development of conditioned fear have not yet been investigated. In the present study, we tracked Purkinje cell activities throughout a fear conditioning procedure and aimed to elucidate further how cerebellar circuits function during the acquisition and expression of conditioned fear. Methods Activities of single Purkinje cells in the corpus cerebelli were tracked throughout a classical fear conditioning procedure in goldfish. A delayed conditioning paradigm was used with cardiac deceleration as the conditioned response. Conditioning-related changes of Purkinje cell responses to a conditioned stimulus and unconditioned stimulus were examined. Results The majority of Purkinje cells sampled responded to the conditioned stimulus by either increasing or decreasing their firing rates before training. Although there were various types of conditioning-related changes in Purkinje cells, more than half of the cells showed suppressed activities in response to the conditioned stimulus after acquisition of conditioned fear. Purkinje cells that showed unconditioned stimulus-coupled complex-spike firings also exhibited conditioning-related suppression of simple-spike responses to the conditioned stimulus. A small number of Purkinje cells showed increased excitatory responses in the acquisition sessions. We found that the magnitudes of changes in the firing frequencies of some Purkinje cells in response to the conditioned stimulus correlated with the magnitudes of the conditioned

  15. Dose-response relation between physical activity and sick leave

    NARCIS (Netherlands)

    Proper, K.I.; Heuvel, S.G. van den; Vroome, E.M. de; Hildebrandt, V.H.; Beek, A.J. van der

    2006-01-01

    Objective: To investigate the dose-response relation between moderate and vigorous physical activity and sick leave in a working population. Methods: Data were used from three large Dutch databases: two continuous, cross sectional surveys among a representative sample of the Dutch population and one

  16. The Necessity of Public Relations for Sustainable Mining Activities

    Science.gov (United States)

    Lee, Hyunbock; Ji, Sangwoo

    2015-04-01

    other hand, in the survey to determine what the greatest difficulties of the current mining activities, 54% of mining companies chose environmental regulations, 26% of mining companies chose conflicts between mine area residents and mining companies. Environmental regulations are may defined as the greatest difficulty of current mining activities. But most of environmental regulation's problems are caused by frictions with residents, because all of South Korean mines are very close to villages. So, the biggest difficulty of mining activities can be defined conflicts between residents and mining companies. Moreover, general people in South Korea including some mining engineers recognize the mining industry as a declined and pollution industry. Without clear understanding of mining activities, any mine developments and policies related to mining activities cannot be made by rational discussions. And, if their recognition is not formed in a rational way, it will be turned to extreme fear or blind hatred. Therefore, to understand mining activities correctly, the effective public relations strategy is necessary such as corporate advertisements or public advertisements.

  17. Systemic complement activation in age-related macular degeneration.

    Directory of Open Access Journals (Sweden)

    Hendrik P N Scholl

    Full Text Available Dysregulation of the alternative pathway (AP of complement cascade has been implicated in the pathogenesis of age-related macular degeneration (AMD, the leading cause of blindness in the elderly. To further test the hypothesis that defective control of complement activation underlies AMD, parameters of complement activation in blood plasma were determined together with disease-associated genetic markers in AMD patients. Plasma concentrations of activation products C3d, Ba, C3a, C5a, SC5b-9, substrate proteins C3, C4, factor B and regulators factor H and factor D were quantified in patients (n = 112 and controls (n = 67. Subjects were analyzed for single nucleotide polymorphisms in factor H (CFH, factor B-C2 (BF-C2 and complement C3 (C3 genes which were previously found to be associated with AMD. All activation products, especially markers of chronic complement activation Ba and C3d (p<0.001, were significantly elevated in AMD patients compared to controls. Similar alterations were observed in factor D, but not in C3, C4 or factor H. Logistic regression analysis revealed better discriminative accuracy of a model that is based only on complement activation markers Ba, C3d and factor D compared to a model based on genetic markers of the complement system within our study population. In both the controls' and AMD patients' group, the protein markers of complement activation were correlated with CFH haplotypes.This study is the first to show systemic complement activation in AMD patients. This suggests that AMD is a systemic disease with local disease manifestation at the ageing macula. Furthermore, the data provide evidence for an association of systemic activation of the alternative complement pathway with genetic variants of CFH that were previously linked to AMD susceptibility.

  18. Bidirectional associations between activity-related parenting practices, and child physical activity, sedentary screen-based behavior and body mass index: a longitudinal analysis

    OpenAIRE

    Sleddens, Ester F. C.; Gubbels, Jessica S.; Kremers, Stef P. J.; van der Plas, Eline; Thijs, Carel

    2017-01-01

    Background It has been generally assumed that activity-related parenting practices influence children?s activity behavior and weight status. However, vice versa parents may also change their parenting behaviors in response to their perceptions of their child?s activity behavior and weight status. This study examined the bidirectional relationships between activity-related parenting practices, and physical activity, sedentary screen-based behavior, and body mass index (BMI) between children?s ...

  19. Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention

    Directory of Open Access Journals (Sweden)

    Andrew T. Ludlow

    2011-01-01

    Full Text Available Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence of the molecular and cellular factors associated with reduced disease risk and increased longevity resulting from physical activity is sparse. A long-standing hypothesis of aging is the telomere hypothesis: as a cell divides, telomeres shorten resulting eventually in replicative senescence and an aged phenotype. Several reports have recently associated telomeres and telomere-related proteins to diseases associated with physical inactivity and aging including cardiovascular disease, insulin resistance, and hypertension. Interestingly several reports have also shown that longer telomeres are associated with higher physical activity levels, indicating a potential mechanistic link between physical activity, reduced age-related disease risk, and longevity. The primary purpose of this review is to discuss the potential importance of physical activity in telomere biology in the context of inactivity- and age-related diseases. A secondary purpose is to explore potential mechanisms and important avenues for future research in the field of telomeres and diseases associated with physical inactivity and aging.

  20. BDNF Methylation and Maternal Brain Activity in a Violence-Related Sample.

    Directory of Open Access Journals (Sweden)

    Dominik A Moser

    Full Text Available It is known that increased circulating glucocorticoids in the wake of excessive, chronic, repetitive stress increases anxiety and impairs Brain-Derived Neurotrophic Factor (BDNF signaling. Recent studies of BDNF gene methylation in relation to maternal care have linked high BDNF methylation levels in the blood of adults to lower quality of received maternal care measured via self-report. Yet the specific mechanisms by which these phenomena occur remain to be established. The present study examines the link between methylation of the BDNF gene promoter region and patterns of neural activity that are associated with maternal response to stressful versus non-stressful child stimuli within a sample that includes mothers with interpersonal violence-related PTSD (IPV-PTSD. 46 mothers underwent fMRI. The contrast of neural activity when watching children-including their own-was then correlated to BDNF methylation. Consistent with the existing literature, the present study found that maternal BDNF methylation was associated with higher levels of maternal anxiety and greater childhood exposure to domestic violence. fMRI results showed a positive correlation of BDNF methylation with maternal brain activity in the anterior cingulate (ACC, and ventromedial prefrontal cortex (vmPFC, regions generally credited with a regulatory function toward brain areas that are generating emotions. Furthermore we found a negative correlation of BDNF methylation with the activity of the right hippocampus. Since our stimuli focus on stressful parenting conditions, these data suggest that the correlation between vmPFC/ACC activity and BDNF methylation may be linked to mothers who are at a disadvantage with respect to emotion regulation when facing stressful parenting situations. Overall, this study provides evidence that epigenetic signatures of stress-related genes can be linked to functional brain regions regulating parenting stress, thus advancing our understanding of

  1. Elementary Physical Education Teachers' Content Knowledge of Physical Activity and Health-Related Fitness

    Science.gov (United States)

    Santiago, Jose A.; Disch, James G.; Morales, Julio

    2012-01-01

    The purpose of this study was to examine elementary physical education teachers' content knowledge of physical activity and health-related fitness. Sixty-four female and 24 male teachers completed the Appropriate Physical Activity and Health-Related Fitness test. Descriptive statistics results indicated that the mean percentage score for the test…

  2. 12 CFR 225.129 - Activities closely related to banking.

    Science.gov (United States)

    2010-01-01

    ... competitive advantage over firms competing with other holding company affiliates. To reduce the possibility... Board's amendment of § 225.4(a), which adds courier services to the list of closely related activities... generally in the provision of transportation services. During the course of the Board's proceedings...

  3. Iodine-129 in the environment of a nuclear fuel reprocessing plant by neutron activation analysis

    International Nuclear Information System (INIS)

    Anderson, T.J.

    1978-01-01

    129 I has been analyzed in both aqueous and soil samples to characterize the environmental impact of the Savannah River Plant (SRP) reprocessing operations. 129 I was quantified by a neutron activation procedure with γ-ray spectrometric detection [Ge(Li)]. For many samples, natural iodine ( 127 I) was also quantified. A wide range of samples can be accommodated by a combustion-based preirradiation isolation technique. 129 I amounts as low as 3.8 fCi can be determined with counting times of less than 30 minutes (s/sub rel/ = 10%). Deposition of 129 I in the environment via aqueous and airborne emissions has been studied. Data from analysis of seepage basin contents, spring water, on-plant streams, and the Savannah River show that 129 I from the seepage basins migrates easily through the soil with the groundwater, eventually reaching the Savannah River. Annual aqueous release rates were estimated to be 16 to 27 mCi/year. Data from analysis of soils from distances up to 159 km from SRP show above background levels of 129 I in both the minimum and maximum airborne transport directions. The soil results are compared with a wind dispersion model. The vertical distribution of 129 I in the soil was determined to a depth of 61 cm

  4. Application of activity theory to analysis of human-related accidents: Method and case studies

    International Nuclear Information System (INIS)

    Yoon, Young Sik; Ham, Dong-Han; Yoon, Wan Chul

    2016-01-01

    This study proposes a new approach to human-related accident analysis based on activity theory. Most of the existing methods seem to be insufficient for comprehensive analysis of human activity-related contextual aspects of accidents when investigating the causes of human errors. Additionally, they identify causal factors and their interrelationships with a weak theoretical basis. We argue that activity theory offers useful concepts and insights to supplement existing methods. The proposed approach gives holistic contextual backgrounds for understanding and diagnosing human-related accidents. It also helps identify and organise causal factors in a consistent, systematic way. Two case studies in Korean nuclear power plants are presented to demonstrate the applicability of the proposed method. Human Factors Analysis and Classification System (HFACS) was also applied to the case studies. The results of using HFACS were then compared with those of using the proposed method. These case studies showed that the proposed approach could produce a meaningful set of human activity-related contextual factors, which cannot easily be obtained by using existing methods. It can be especially effective when analysts think it is important to diagnose accident situations with human activity-related contextual factors derived from a theoretically sound model and to identify accident-related contextual factors systematically. - Highlights: • This study proposes a new method for analysing human-related accidents. • The method was developed based on activity theory. • The concept of activity system model and contradiction was used in the method. • Two case studies in nuclear power plants are presented. • The method is helpful to consider causal factors systematically and comprehensively.

  5. The Relation between Childhood Spatial Activities and Spatial Abilities in Adulthood

    Science.gov (United States)

    Doyle, Randi A.; Voyer, Daniel; Cherney, Isabelle D.

    2012-01-01

    This study investigated the relation between childhood spatial activities and cognitive gender differences in adults through the validation of the Childhood Activities Questionnaire developed by Cherney and Voyer (2010). A sample of 403 (133 males, 270 females) undergraduates in Introductory Psychology courses at University of New Brunswick, NB,…

  6. Ecological analysis of college women's physical activity and health-related quality of life.

    Science.gov (United States)

    Zhang, Tao; Dunn, Jacqueline; Morrow, James; Greenleaf, Christy

    2018-03-01

    Despite significant health benefits of regular physical activity, over 60 percent of college women do not meet recommended physical activity guidelines to promote their health and health-related quality of life (HRQoL), a comprehensive construct including physical and psychosocial health functioning. The major purpose of this study was to examine the influences of individual (e.g., self-efficacy, enjoyment), social (e.g., family and friend support), and physical environmental factors (e.g., crime safety) on college women's physical activity and HRQoL. Participants were 235 (Mean age = 21.0 years) college women from a public research university located in the southwest region of the United States. They completed validated surveys assessing their perceptions of physical activity, HRQoL, and social ecological factors during the spring semester of 2012. The findings of three multiple linear regressions, entering individual factors first, followed by social and physical environmental factors, revealed that self-efficacy and crime safety were significantly related to physical activity. For HRQoL-physical functioning, significant factors were self-efficacy, enjoyment, and crime safety. Enjoyment was the only factor related to HRQoL-psychosocial functioning. These findings indicated that physical activity professionals need to foster safe environments, enhance self-efficacy, and provide enjoyable activities to promote college women's physical activity and HRQoL.

  7. Pulse tube coolers for Meteosat third generation

    International Nuclear Information System (INIS)

    Butterworth, James; Aigouy, Gérald; Chassaing, Clement; Debray, Benoît; Huguet, Alexandre

    2014-01-01

    Air Liquide's Large Pulse Tube Coolers (LPTC) will be used to cool the focal planes of the Infrared Sounder (IRS) and Flexible Combined Imager (FCI) instruments aboard the ESA/Eumetsat satellites Meteosat Third Generation (MTG). This cooler consists of an opposed piston linear compressor driving a pulse tube cold head and the associated drive electronics including temperature regulation and vibration cancellation algorithms. Preparations for flight qualification of the cooler are now underway. In this paper we present results of the optimization and qualification activities as well as an update on endurance testing

  8. Fall-related activity avoidance in relation to a history of falls or near falls, fear of falling and disease severity in people with Parkinson's disease.

    Science.gov (United States)

    Kader, Manzur; Iwarsson, Susanne; Odin, Per; Nilsson, Maria H

    2016-06-02

    There is limited knowledge concerning fall-related activity avoidance in people with Parkinson's disease (PD); such knowledge would be of importance for the development of more efficient PD-care and rehabilitation. This study aimed to examine how fall-related activity avoidance relates to a history of self-reported falls/near falls and fear of falling (FOF) as well as to disease severity in people with PD. Data were collected from 251 (61 % men) participants with PD; their median (min-max) age and PD duration were 70 (45-93) and 8 (1-43) years, respectively. A self-administered postal survey preceded a home visit which included observations, clinical tests and interview-administered questionnaires. Fall-related activity avoidance was assessed using the modified Survey of Activities and Fear of Falling in the Elderly (mSAFFE) as well as by using a dichotomous (Yes/No) question. Further dichotomous questions concerned: the presence of FOF and the history (past 6 months) of falls or near falls, followed by stating the number of incidents. Disease severity was assessed according to the Hoehn and Yahr (HY) stages. In the total sample (n = 251), 41 % of the participants reported fall-related activity avoidance; the median mSAFFE score was 22. In relation to a history of fall, the proportions of participants (p fall-related activity avoidance were: non-fallers (30 %), single fallers (50 %) and recurrent fallers, i.e. ≥ 2 falls (57 %). Among those that reported near falls (but no falls), 51 % (26 out of 51) reported fall-related activity avoidance. Of those that reported FOF, 70 % reported fall-related activity avoidance. Fall-related activity avoidance ranged from 24 % in the early PD-stage (HY I) to 74 % in the most severe stages (HY IV-V). Results indicate that fall-related activity avoidance may be related to a history of self-reported falls/near falls, FOF and disease severity in people with PD. Importantly, fall-related activity avoidance is

  9. Global development of advanced nuclear power plants, and related IAEA activities

    International Nuclear Information System (INIS)

    2006-09-01

    Renewed interest in the potential of nuclear energy to contribute to a sustainable worldwide energy mix is underlining the IAEA's statutory role in fostering the peaceful uses of nuclear energy, in particular the need for effective exchanges of information and collaborative research and technology development among Member States on advanced nuclear power technologies deployable in the near term as well as in the longer term. For applications in the medium to longer term, with rising expectations for the role of nuclear energy in the future, technological innovation has become a strong focus of nuclear power technology developments by many Member States. To meet Member States' needs, the IAEA conducts activities to foster information exchange and collaborative research and development in the area of advanced nuclear reactor technologies. These activities include coordination of collaborative research, organization of international information exchange, and analyses of globally available technical data and results, with a focus on reducing nuclear power plant capital costs and construction periods while further improving performance, safety and proliferation resistance. In other activities, evolutionary and innovative advances are catalyzed for all reactor lines such as advanced water cooled reactors, high temperature gas cooled reactors, liquid metal cooled reactors and accelerator driven systems, including small and medium sized reactors. In addition, there are activities related to other applications of nuclear energy such as seawater desalination, hydrogen production, and other process heat applications. This brochure summarizes the worldwide status and the activities related to advanced nuclear power technology development and related IAEA activities. It includes a list of the collaborative research and development projects conducted by the IAEA, as well as of the status reports and other publications produced

  10. Interest of active posturography to detect age-related and early Parkinson's disease-related impairments in mediolateral postural control.

    Science.gov (United States)

    Bonnet, Cédrick T; Delval, Arnaud; Defebvre, Luc

    2014-11-15

    Patients with Parkinson's disease display impairments of postural control most particularly in active, challenging conditions. The objective of the present study was to analyze early signs of disease-related and also age-related impairments in mediolateral body extension and postural control. Fifty-five participants (18 Hoehn and Yahr stage 2 patients in the off-drug condition, 18 healthy elderly control subjects, and 19 young adults) were included in the study. The participants performed a quiet stance task and two active tasks that analyzed the performance in mediolateral body motion: a limit of stability and a rhythmic weight shift task. As expected, the patients displayed significantly lower and slower body displacement (head, neck, lower back, center of pressure) than elderly control subjects when performing the two body excursion tasks. However, the behavioral variability in both tasks was similar between the groups. Under these active conditions, the patients showed significantly lower contribution of the hip postural control mechanisms compared with the elderly control subjects. Overall, the patients seemed to lower their performance in order to prevent a mediolateral postural instability. However, these patients, at an early stage of their disease, were not unstable in quiet stance. Complementarily, elderly control subjects displayed slower body performance than young adults, which therefore showed an additional age-related impairment in mediolateral postural control. Overall, the study illustrated markers of age-related and Parkinson's disease impairments in mediolateral postural control that may constrain everyday activities in elderly adults and even more in patients with Parkinson's disease. Copyright © 2014 the American Physiological Society.

  11. Motivation-related predictors of physical activity engagement and vitality in rheumatoid arthritis patients

    Directory of Open Access Journals (Sweden)

    Chen-an Yu

    2015-08-01

    Full Text Available This study tests the Basic Psychological Needs Theory (within the Self-determination framework, in relation to the prediction of physical activity and well-being among rheumatoid arthritis patients. Motivation regulations for physical activity were also considered in the process model. A total of 207 patients (150 females, mean age = 58 ± 11 years completed a questionnaire pack and structural equation modelling was used to test expected relationships. Autonomy support provided by important other(s regarding physical activity positively predicted rheumatoid arthritis patients’ need satisfaction which positively related to autonomous reasons for physical activity participation. Autonomous motivation positively predicted reported physical activity participation levels and feelings of vitality.

  12. Sex Differences in Brain Activity Related to General and Emotional Intelligence

    Science.gov (United States)

    Jausovec, Norbert; Jausovec, Ksenija

    2005-01-01

    The study investigated gender differences in resting EEG (in three individually determined narrow [alpha] frequency bands) related to the level of general and emotional intelligence. Brain activity of males decreased with the level of general intelligence, whereas an opposite pattern of brain activity was observed in females. This difference was…

  13. Life Cycle of the Salmon. Ocean Related Curriculum Activities.

    Science.gov (United States)

    Tarabochia, Kathy

    The ocean affects all of our lives. Therefore, awareness of and information about the interconnections between humans and oceans are prerequisites to making sound decisions for the future. Project ORCA (Ocean Related Curriculum Activities) has developed interdisciplinary curriculum materials designed to meet the needs of students and teachers…

  14. Relational complexity modulates activity in the prefrontal cortex during numerical inductive reasoning: an fMRI study.

    Science.gov (United States)

    Feng, Xiao; Peng, Li; Chang-Quan, Long; Yi, Lei; Hong, Li

    2014-09-01

    Most previous studies investigating relational reasoning have used visuo-spatial materials. This fMRI study aimed to determine how relational complexity affects brain activity during inductive reasoning, using numerical materials. Three numerical relational levels of the number series completion task were adopted for use: 0-relational (e.g., "23 23 23"), 1-relational ("32 30 28") and 2-relational ("12 13 15") problems. The fMRI results revealed that the bilateral dorsolateral prefrontal cortex (DLPFC) showed enhanced activity associated with relational complexity. Bilateral inferior parietal lobule (IPL) activity was greater during the 1- and 2-relational level problems than during the 0-relational level problems. In addition, the left fronto-polar cortex (FPC) showed selective activity during the 2-relational level problems. The bilateral DLPFC may be involved in the process of hypothesis generation, whereas the bilateral IPL may be sensitive to calculation demands. Moreover, the sensitivity of the left FPC to the multiple relational problems may be related to the integration of numerical relations. The present study extends our knowledge of the prefrontal activity pattern underlying numerical relational processing. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Relation of Age at Menarche to Physical Activity

    Directory of Open Access Journals (Sweden)

    Egreta Peja

    2016-10-01

    Full Text Available The aim of this study is to determine whether regular physical activity during early puberty is influential in preventing early menarche. This cross sectional study was carried out on 102 post-menarcheal girls aged 11–20 (14.79±0.33. 51 of them were already engaged in competitive sport activities prior to the onset of menstruation (group 1, while the others got engaged in such activities after the onset of menstruation (group 2. All participants provided the year and the month of their first menstrual period. First, we estimated the equality of dispersion between the two groups, by conducting Two Samples for Variances F-test. Second, because no homogeneity of variances between groups was found, they were compared by using Two Samples Assuming Unequal Variances t-test. The difference between groups is statistically significant, as the t statistics (=2.883 is greater than both critical t statistics (one-tail=1.664 two-tail=1.990 and the p value less than 0.05 in both cases (one-tail=0.002 two-tail=0.005. None of the girls in the first group starts to menstruate before 11 years of age and 90% of them are menstruating by age 14, with a median age of 12.95±0.35 years. Age of menarche is lower in the second group with a median age of 12.25±0.31 years, thus approximately 8 months lower than median age for the first group. 11.76% of the girls in the second group start to menstruate before 11 years of age and 90% of them are menstruating by age 13. It is rather, the decline in early matures among those engaged in regular physical activity prior to the onset of menses, that makes the statistically significant correlation between physical activity and age at menarche practically meaningful. Relatively early matures (<11 years have been found to be slightly shorter but up to 5.5 kg heavier in adulthood than are late matures. In addition, a relatively young age at menarche has been associated with an increased risk for breast cancer and spontaneous

  16. Hippocampus activation related to 'real-time' processing of visuospatial change.

    Science.gov (United States)

    Beudel, M; Leenders, K L; de Jong, B M

    2016-12-01

    The delay associated with cerebral processing time implies a lack of real-time representation of changes in the observed environment. To bridge this gap for motor actions in a dynamical environment, the brain uses predictions of the most plausible future reality based on previously provided information. To optimise these predictions, adjustments to actual experiences are necessary. This requires a perceptual memory buffer. In our study we gained more insight how the brain treats (real-time) information by comparing cerebral activations related to judging past-, present- and future locations of a moving ball, respectively. Eighteen healthy subjects made these estimations while fMRI data was obtained. All three conditions evoked bilateral dorsal-parietal and premotor activations, while judgment of the location of the ball at the moment of judgment showed increased bilateral posterior hippocampus activation relative to making both future and past judgments at the one-second time-sale. Since the condition of such 'real-time' judgments implied undistracted observation of the ball's actual movements, the associated hippocampal activation is consistent with the concept that the hippocampus participates in a top-down exerted sensory gating mechanism. In this way, it may play a role in novelty (saliency) detection. Copyright © 2016 Elsevier B.V. All rights reserved.

  17. The Relation of Personality Traits Wth Depression Severity in Active and Non-Active Elderly Women in Tehran City

    OpenAIRE

    Mohammad Ali Aslankhani; Ahmad Farokhi; Parvane Shamsipour Dehkordi; Amir Shams; Mohammad Reza Ghasemian Moghaddam

    2010-01-01

    Objectives: The purpose of this study was to investigate the relation of personality traits with depression in active and non – active elderly women in Tehran city. Methods & Materials: The present research is descriptive–correlation. For this purpose, 188 elderly women (94 active and 94 non - active elders) in the age range of 63-82 in Tehran city availably selected as statistical sample. Measurement instrument were demographic questionnaire, Beck depression questionnaire and...

  18. Eesti esimese rahvusvahelise IPO võistluse kuld läks Lätti / Merike Kungla

    Index Scriptorium Estoniae

    Kungla, Merike

    2013-01-01

    Teenistuskoerte kolmevõistluse Eesti meistrivõistlustelt Rakveres ja Eesti esimeselt FCI CACIT'i õigusega rahvusvaheliselt IPO võistluselt. Arvamust avaldavad Aivo Oblikas ja Pentti Rapila. Tulemused vt lk 19

  19. Adolescents' and young adults' physical activity related to built environment

    Directory of Open Access Journals (Sweden)

    Armando Cocca

    2015-06-01

    Full Text Available Objectives. This study aims to analyse physical activity (PA levels of high school and university students; to estimate their perception of built environment with regard to physical PA; and to assess the relation between PA and built environment. Methods. A sociological cross-sectional study with non-experimental design was applied. The International Physical Activity Questionnaire and the Built Environment Characteristics Questionnaire were filled in by a sample of 1.862 students from high schools and the university in Granada, Spain. Results. High school students were significantly more active than university students, the latter reaching insufficient levels of PA. Nevertheless, they consider Granada as a good context for carrying out outdoor exercise. No relations were found between PA levels and built environment. Conclusion. The discrepant outcomes for PA levels and perceived built environment suggest the need of interventions focused on making youth aware of the possibilities that an environment provides to them for exercising. Consequently, environment could have an impact on their health at the same time as youth learn to respect it.

  20. Surface sediment quality relative to port activities: A contaminant-spectrum assessment.

    Science.gov (United States)

    Yu, Shen; Hong, Bing; Ma, Jun; Chen, Yongshan; Xi, Xiuping; Gao, Jingbo; Hu, Xiuqin; Xu, Xiangrong; Sun, Yuxin

    2017-10-15

    Ports are facing increasing environmental concerns with their importance to the global economy. Numerous studies indicated sediment quality deterioration in ports; however, the deterioration is not discriminated for each port activity. This study investigated a spectrum of contaminants (metals and organic pollutants) in surface sediments at 20 sampling points in Port Ningbo, China, one of the top five world ports by volume. The spectrum of contaminants (metals and organic pollutants) was quantified following marine sediment quality guidelines of China and USA and surface sediment quality was assessed according to thresholds of the two guidelines. Coupling a categorical matrix of port activities with the matrix of sedimentary contaminants revealed that contaminants were highly associated with the port operations. Ship repair posed a severe chemical risk to sediment. Operations of crude oil and coal loadings were two top activities related to organic pollutants in sediments while port operations of ore and container loadings discharged metals. Among the 20 sampling points, Cu, Zn, Pb, and DDT and its metabolites were the priority contaminants influencing sediment quality. Overall, surface sediments in Port Ningbo had relatively low environmental risks but ship repair is an environmental concern that must be addressed. This study provides a practical approach for port activity-related quality assessment of surface sediments in ports that could be applicable in many world sites. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. A transient single particle model under FCI conditions

    Institute of Scientific and Technical Information of China (English)

    LI Xiao-Yan; SHANG Zhi; XU Ji-Jun

    2005-01-01

    The paper is focused on the coupling effect between film boiling heat transfer and evaporation drag around a hot-particle in cold liquid. Based on the continuity, momentum and energy equations of the vapor film, a transient two-dimensional single particle model has been established. This paper contains a detailed description of HPMC (High-temperature Particle Moving in Coolant) model for studying some aspects of the premixing stage of fuel-coolant interactions (FCIs). The transient process of high-temperature particles moving in coolant can be simulated. Comparisons between the experiment results and the calculations using HPMC model demonstrate that HPMC model achieves a good agreement in predicting the time-varying characteristic of high-temperature spheres moving in coolant.

  2. The relation between self-determination and retirement satisfaction among active retired individuals.

    Science.gov (United States)

    Stephan, Yannick; Fouquereau, Evelyne; Fernandez, Anne

    2008-01-01

    Little is known about the motivational forces leading retired individuals to engage in post-retirement activities and how they could be related to satisfaction with retirement. Using the self-determination framework, the purpose of the present exploratory study was to examine the nature of active retirees' motivation and its impact on satisfaction with life in retirement. The Global Motivation Scale and measures of satisfaction with retirement were administered to 150 active retired individuals engaged in organized post-retirement activities in a University-based organization. Results revealed that these individuals were mainly characterized by higher levels of intrinsic motivation for knowledge, stimulation and accomplishment, rather than extrinsic dimensions. Regression analysis further demonstrated that intrinsic motivation for both accomplishment and stimulation were positively related to satisfaction with retirement, over and above the significant contribution of time since retirement, anticipated satisfaction with retirement, and subjective health. This exploratory study highlights the motivational mechanisms through which post-retirement behaviors could positively influence satisfaction with life in retirement among active retirees.

  3. Antileishmanial activities of dihydrochalcones from piper elongatum and synthetic related compounds. Structural requirements for activity.

    Science.gov (United States)

    Hermoso, Alicia; Jiménez, Ignacio A; Mamani, Zulma A; Bazzocchi, Isabel L; Piñero, José E; Ravelo, Angel G; Valladares, Basilio

    2003-09-01

    Two dihydrochalcones (1 and 2) were isolated from Piper elongatum Vahl by activity-guided fractionation against extracellular promastigotes of Leishmania braziliensis in vitro. Their structures were elucidated by spectral analysis, including homonuclear and heteronuclear correlation NMR experiments. Derivatives 3-7 and 20 synthetic related compounds (8-27) were also assayed to establish the structural requirements for antileishmanial activity. Compounds 1-11 that proved to be more active that ketoconazol, used as positive control, were further assayed against promastigotes of Leishmania tropica and Leishmania infantum. Compounds 7 and 11, with a C(6)-C(3)-C(6) system, proved to be the most promising compounds, with IC(50) values of 2.98 and 3.65 microg/mL, respectively, and exhibited no toxic effect on macrophages (around 90% viability). Correlation between the molecular structures and antileishmanial activity is discussed in detail.

  4. NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration

    Directory of Open Access Journals (Sweden)

    Jiangyuan Gao

    2015-01-01

    Full Text Available Age-related macular degeneration (AMD is the leading cause of legal blindness in the elderly in industrialized countries. AMD is a multifactorial disease influenced by both genetic and environmental risk factors. Progression of AMD is characterized by an increase in the number and size of drusen, extracellular deposits, which accumulate between the retinal pigment epithelium (RPE and Bruch’s membrane (BM in outer retina. The major pathways associated with its pathogenesis include oxidative stress and inflammation in the early stages of AMD. Little is known about the interactions among these mechanisms that drive the transition from early to late stages of AMD, such as geographic atrophy (GA or choroidal neovascularization (CNV. As part of the innate immune system, inflammasome activation has been identified in RPE cells and proposed to be a causal factor for RPE dysfunction and degeneration. Here, we will first review the classic model of inflammasome activation, then discuss the potentials of AMD-related factors to activate the inflammasome in both nonocular immune cells and RPE cells, and finally introduce several novel mechanisms for regulating the inflammasome activity.

  5. Eesti koerad hiilgavad sõnakuulelikkusega / Marko Tiidemann

    Index Scriptorium Estoniae

    Tiidelepp, Marko

    2014-01-01

    Koerte sõnakuulelikkuse MMist, mis toimus 8.-10. augustini Helsingis, FCI World Dog Show raames. Eestist osales neli koera ja võistlejat Anne Tammiksalu, Helena Trus, Natalia Garastsenko, Svetlana Zolotnikova

  6. Time Well Spent? Relating Television Use to Children’s Free-Time Activities

    Science.gov (United States)

    Vandewater, Elizabeth A.; Bickham, David S.; Lee, June H.

    2010-01-01

    OBJECTIVES This study assessed the claim that children’s television use interferes with time spent in more developmentally appropriate activities. METHODS Data came from the first wave of the Child Development Supplement, a nationally representative sample of children aged 0 to 12 in 1997 (N = 1712). Twenty-four-hour time-use diaries from 1 randomly chosen weekday and 1 randomly chosen weekend day were used to assess children’s time spent watching television, time spent with parents, time spent with siblings, time spent reading (or being read to), time spent doing homework, time spent in creative play, and time spent in active play. Ordinary least squares multiple regression was used to assess the relationship between children’s television use and time spent pursuing other activities. RESULTS Results indicated that time spent watching television both with and without parents or siblings was negatively related to time spent with parents or siblings, respectively, in other activities. Television viewing also was negatively related to time spent doing homework for 7- to 12-year-olds and negatively related to creative play, especially among very young children (younger than 5 years). There was no relationship between time spent watching television and time spent reading (or being read to) or to time spent in active play. CONCLUSIONS The results of this study are among the first to provide empirical support for the assumptions made by the American Academy of Pediatrics in their screen time recommendations. Time spent viewing television both with and without parents and siblings present was strongly negatively related to time spent interacting with parents or siblings. Television viewing was associated with decreased homework time and decreased time in creative play. Conversely, there was no support for the widespread belief that television interferes with time spent reading or in active play. PMID:16452327

  7. Options for Diversification in Tobacco Farming and Related Activities ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    5 janv. 2012 ... This project aims to provide the national working group with data on the socioeconomic status of the population engaged in tobacco farming and related activities such as bidi rolling and tendu leaf plucking; identify feasible alternative livelihoods; and design an intervention to facilitate a gradual shift to other ...

  8. Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology

    Science.gov (United States)

    Yohn, Samantha E.; López-Cruz, Laura; San Miguel, Noemí; Correa, Mercè

    2016-01-01

    Abstract Motivation has been defined as the process that allows organisms to regulate their internal and external environment, and control the probability, proximity and availability of stimuli. As such, motivation is a complex process that is critical for survival, which involves multiple behavioural functions mediated by a number of interacting neural circuits. Classical theories of motivation suggest that there are both directional and activational aspects of motivation, and activational aspects (i.e. speed and vigour of both the instigation and persistence of behaviour) are critical for enabling organisms to overcome work-related obstacles or constraints that separate them from significant stimuli. The present review discusses the role of brain dopamine and related circuits in behavioural activation, exertion of effort in instrumental behaviour, and effort-related decision-making, based upon both animal and human studies. Impairments in behavioural activation and effort-related aspects of motivation are associated with psychiatric symptoms such as anergia, fatigue, lassitude and psychomotor retardation, which cross multiple pathologies, including depression, schizophrenia, and Parkinson’s disease. Therefore, this review also attempts to provide an interdisciplinary approach that integrates findings from basic behavioural neuroscience, behavioural economics, clinical neuropsychology, psychiatry, and neurology, to provide a coherent framework for future research and theory in this critical field. Although dopamine systems are a critical part of the brain circuitry regulating behavioural activation, exertion of effort, and effort-related decision-making, mesolimbic dopamine is only one part of a distributed circuitry that includes multiple neurotransmitters and brain areas. Overall, there is a striking similarity between the brain areas involved in behavioural activation and effort-related processes in rodents and in humans. Animal models of effort-related

  9. JAEA's activities relating the Fukushima Nuclear Plant accident

    International Nuclear Information System (INIS)

    Tagawa, Akihiro

    2012-01-01

    JAEA started the activities relating to the Fukushima nuclear plant accident immediately after the Great East Japan Earthquake. The Office of Fukushima Partnership Operations for Environmental Remediation was opened and the JAEA staff was stationed as the base of cooperation with other organizations. It is conducting environmental radiation monitoring, environmental radioactivity analyses, resident public consulting, and demonstration of decontamination technology. Experts of JAEA are providing technical advice and supports to the Nuclear Safety Commission of Japan and the Ministry of Education, Culture and Sports. Furthermore, the water radiolysis leading to hydrogen gas evolution by Cs 137 adsorbed zeolite and the technique for radioactive waste process and its disposal of fuel debris are being studied. JAEA's Nuclear Emergency Assistance and Training Center (NEAT) is acting as a center of these supporting activities of JAEA. (S. Ohno)

  10. Different responses of spontaneous and stimulus-related alpha activity to ambient luminance changes.

    Science.gov (United States)

    Benedetto, Alessandro; Lozano-Soldevilla, Diego; VanRullen, Rufin

    2017-12-04

    Alpha oscillations are particularly important in determining our percepts and have been implicated in fundamental brain functions. Oscillatory activity can be spontaneous or stimulus-related. Furthermore, stimulus-related responses can be phase- or non-phase-locked to the stimulus. Non-phase-locked (induced) activity can be identified as the average amplitude changes in response to a stimulation, while phase-locked activity can be measured via reverse-correlation techniques (echo function). However, the mechanisms and the functional roles of these oscillations are far from clear. Here, we investigated the effect of ambient luminance changes, known to dramatically modulate neural oscillations, on spontaneous and stimulus-related alpha. We investigated the effect of ambient luminance on EEG alpha during spontaneous human brain activity at rest (experiment 1) and during visual stimulation (experiment 2). Results show that spontaneous alpha amplitude increased by decreasing ambient luminance, while alpha frequency remained unaffected. In the second experiment, we found that under low-luminance viewing, the stimulus-related alpha amplitude was lower, and its frequency was slightly faster. These effects were evident in the phase-locked part of the alpha response (echo function), but weaker or absent in the induced (non-phase-locked) alpha responses. Finally, we explored the possible behavioural correlates of these modulations in a monocular critical flicker frequency task (experiment 3), finding that dark adaptation in the left eye decreased the temporal threshold of the right eye. Overall, we found that ambient luminance changes impact differently on spontaneous and stimulus-related alpha expression. We suggest that stimulus-related alpha activity is crucial in determining human temporal segmentation abilities. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  11. A large-area grid ionisation chamber with high resolution for the measurement of alpha sources in samples with low specific activity

    International Nuclear Information System (INIS)

    Hoetzl, H.; Winkler, R.

    1978-06-01

    Construction and properties of a gridded ionization chamber for α-paricle spectrometry of low-level large-area samples are presented. Great importance was attached to high spectrometric resolution, low background, long-term stability, simple construction and operation, and easy decontamination if necessary. Using modern charge-sensitive preamplifiers spectrometric resolution is 20,6 keV FWHM (0,4%) at 5,30 MeV over the total effective area of 300 m 2 . Counting gas is an argon-methane mixture (P-10 gas) at atmospheric pressure. Background is 13 cph in the energy interval from 4 to 6 MeV and minimum detectable activity is 0.01 pCi Pu-239 at 1000 min measuring time. Ionization chambers of this type are used for direct α-spectrometric surveillance of long-lived α-emitting nuclides in the atmosphere after electrostatic deposition of the aerosols and for the determination of α-emitting nuclides in the emissions of nuclear power plants. After plasma ashing of the aerosols on filters from the stack monitoring system the minimum detectable concentration of e.g. Pu-239/240 in the gaseous effluent of a nuclear power plant is about 0.1 fCi per m 3 . (orig.) [de

  12. Petroleum related business activities in Hordaland - competence, flexibility and future possibilities

    International Nuclear Information System (INIS)

    Osland, Ove

    2004-06-01

    The aim of the study has been to determine the future conditions of the supply business in Hordaland for petroleum related activities, international competition and on markets outside the Norwegian shelf. In addition it is focused on the adjustment possibilities of the companies during the expected decrease of activity on the Norwegian continental shelf. The report is based on a questionnaire to the company leadership. In 2003 there was 15073 persons employed in the petroleum activities in Hordaland. Out of this the supplier activities account for 10500 employees which is 4.7 % of the total employment in the county. Service deliveries to the shelf are included in the figure. The productivity related competence in these companies is substantial. The work force has a high educational level where more than half has an education of college or higher. Most of the firms have been in the industry for a long time. A substantial part of the suppliers in Hordaland is internationally competitive and participates globally. The companies are to a varying degree specialized for petroleum activities but most of them get their income largely from the petroleum market. A substantial number of companies inform that they would participate in the foreign petroleum market when decrease of activities on the Norwegian shelf occurs. The majority of the companies have however, the capability to adjust to other markets than petroleum exploitation

  13. Factors Related to Meeting Physical Activity Guidelines in Active College Students: A Social Cognitive Perspective

    Science.gov (United States)

    Farren, G. L.; Zhang, T.; Martin, S. B.; Thomas, K. T.

    2017-01-01

    Objective: To examine the relations of sex, exercise self-efficacy, outcome expectations, and social support with meeting physical activity guidelines (PAGs). Participants: Three hundred ninety-six college students participated in this study in the summer 2013. Methods: Students completed online questionnaires that assessed physical activity…

  14. Medicinal plant activity on Helicobacter pylori related diseases.

    Science.gov (United States)

    Wang, Yuan-Chuen

    2014-08-14

    More than 50% of the world population is infected with Helicobacter pylori (H. pylori). The bacterium highly links to peptic ulcer diseases and duodenal ulcer, which was classified as a group I carcinogen in 1994 by the WHO. The pathogenesis of H. pylori is contributed by its virulence factors including urease, flagella, vacuolating cytotoxin A (VacA), cytotoxin-associated gene antigen (Cag A), and others. Of those virulence factors, VacA and CagA play the key roles. Infection with H. pylori vacA-positive strains can lead to vacuolation and apoptosis, whereas infection with cagA-positive strains might result in severe gastric inflammation and gastric cancer. Numerous medicinal plants have been reported for their anti-H. pylori activity, and the relevant active compounds including polyphenols, flavonoids, quinones, coumarins, terpenoids, and alkaloids have been studied. The anti-H. pylori action mechanisms, including inhibition of enzymatic (urease, DNA gyrase, dihydrofolate reductase, N-acetyltransferase, and myeloperoxidase) and adhesive activities, high redox potential, and hydrophilic/hydrophobic natures of compounds, have also been discussed in detail. H. pylori-induced gastric inflammation may progress to superficial gastritis, atrophic gastritis, and finally gastric cancer. Many natural products have anti-H. pylori-induced inflammation activity and the relevant mechanisms include suppression of nuclear factor-κB and mitogen-activated protein kinase pathway activation and inhibition of oxidative stress. Anti-H. pylori induced gastric inflammatory effects of plant products, including quercetin, apigenin, carotenoids-rich algae, tea product, garlic extract, apple peel polyphenol, and finger-root extract, have been documented. In conclusion, many medicinal plant products possess anti-H. pylori activity as well as an anti-H. pylori-induced gastric inflammatory effect. Those plant products have showed great potential as pharmaceutical candidates for H. pylori

  15. ict and quality of teaching–learning related activities in primary ...

    African Journals Online (AJOL)

    Irene

    (ICT) enhance teaching learning related activities in primary schools in Ogoja education zone of Cross. River State ... A sample of six hundred and twenty ... Based on the findings of the study, it was recommended that ... video conferencing).

  16. Guide related to the management of activities in the vicinity of INBs - Project

    International Nuclear Information System (INIS)

    2011-01-01

    This document aims at proposing a national framework for local dialogue on the management of activities in the vicinity of nuclear sites. According to official documents, this dialogue between local actors and public services, based on risk characterization, aims at examining peculiarities and challenges of the concerned territory, and at identifying the most adapted perspectives for economic development while taking risks related to nuclear activities into account. The document first gives an overview of modalities for the taking of the nuclear risk into account. It proposes some definitions related to these issues, indicates general principles of management of activities in the vicinity of basic nuclear installations, and presents some general rules regarding project vulnerability, current projects, road infrastructures, and outdoor temporary events. The next part of the report addresses issues related to local dialogue: roles and missions of the different actors, expected approach at the local level (risk characterization, definition of the area of activity management, territory pre-diagnosis, elaboration of the 'bringing to attention', exchanges with local actors). Appendices present the legal context related to risk management, and a model of requirements specification for a territory pre-diagnosis

  17. Processing of action- but not stimulus-related prediction errors differs between active and observational feedback learning.

    Science.gov (United States)

    Kobza, Stefan; Bellebaum, Christian

    2015-01-01

    Learning of stimulus-response-outcome associations is driven by outcome prediction errors (PEs). Previous studies have shown larger PE-dependent activity in the striatum for learning from own as compared to observed actions and the following outcomes despite comparable learning rates. We hypothesised that this finding relates primarily to a stronger integration of action and outcome information in active learners. Using functional magnetic resonance imaging, we investigated brain activations related to action-dependent PEs, reflecting the deviation between action values and obtained outcomes, and action-independent PEs, reflecting the deviation between subjective values of response-preceding cues and obtained outcomes. To this end, 16 active and 15 observational learners engaged in a probabilistic learning card-guessing paradigm. On each trial, active learners saw one out of five cues and pressed either a left or right response button to receive feedback (monetary win or loss). Each observational learner observed exactly those cues, responses and outcomes of one active learner. Learning performance was assessed in active test trials without feedback and did not differ between groups. For both types of PEs, activations were found in the globus pallidus, putamen, cerebellum, and insula in active learners. However, only for action-dependent PEs, activations in these structures and the anterior cingulate were increased in active relative to observational learners. Thus, PE-related activity in the reward system is not generally enhanced in active relative to observational learning but only for action-dependent PEs. For the cerebellum, additional activations were found across groups for cue-related uncertainty, thereby emphasising the cerebellum's role in stimulus-outcome learning. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Dog ownership and health-related physical activity among Japanese adults.

    Science.gov (United States)

    Oka, Koichiro; Shibata, Ai

    2009-07-01

    Dog ownership appears to have associated health benefits as a result of increased physical activity through dog walking. This study examined the association between dog ownership and health-related physical activity among Japanese adults. Male and female respondents to an Internet-based cross-sectional survey were divided into the following groups: dog owner (DOG), nondog pet owner (NDOG), and nonpet owner (NPOG). Moderate and vigorous physical activity amount (MVPA), walking amount (Walking), and sedentary behavior time (SB) were estimated from the International Physical Activity Questionnaire. Analyses of covariance and logistic regression analysis were used. The differences in MVPA, Walking, and SB were statistically significant among the three groups. DOG had a significantly greater amount of MVPA than NDOG and NPOG. DOG also had a significantly greater amount of Walking and less SB time than NPOG, and DOG was 1.5 times more likely to meet the physical activity recommendation than NDOG and NPOG. The dog owners had higher physical activity levels than owners of other kinds of pets and those without any pets, suggesting that dogs may play a major role in promoting physical activity. However, only 30% of the dog owners met the recommended criteria for physical activity.

  19. Bidirectional associations between activity-related parenting practices, and child physical activity, sedentary screen-based behavior and body mass index: a longitudinal analysis.

    Science.gov (United States)

    Sleddens, Ester F C; Gubbels, Jessica S; Kremers, Stef P J; van der Plas, Eline; Thijs, Carel

    2017-07-06

    It has been generally assumed that activity-related parenting practices influence children's activity behavior and weight status. However, vice versa parents may also change their parenting behaviors in response to their perceptions of their child's activity behavior and weight status. This study examined the bidirectional relationships between activity-related parenting practices, and physical activity, sedentary screen-based behavior, and body mass index (BMI) between children's age of 5 and 7 years. Three scales of the Activity-related Parenting Questionnaire (i.e. 'restriction of sedentary behavior', 'stimulation of physical activity', and 'monitoring of physical activity') were completed by 1694 parents of the Dutch KOALA Birth Cohort Study at the child's age of around 5 and again around age 7. Physical activity, sedentary screen-based behavior and BMI were measured at both ages as well. Linear regression models were used to estimate the bidirectional associations between each parenting practice and the child's physical activity levels, sedentary screen-based behavior and BMI z-scores. Several parenting practices at age 5 predicted child physical activity, sedentary screen-based behavior, and BMI z-scores at age 7. Restriction of sedentary behavior positively predicted child BMI and sedentary screen-based behavior, whereas this practice negatively predicted child physical activity. In addition, stimulation of physical activity at age 5 was significantly associated with higher levels of child physical activity at age 7. The following child factors at age 5 predicted parenting practices at age 7: Child physical activity positively predicted parental stimulation of physical activity and monitoring activities. Sedentary screen-based behavior was associated with lower parental stimulation to be active. Findings generally revealed that parents and children mutually influence each other's behavior. A reinforcing feedback loop was present between parental stimulation

  20. Age-related patterns of vigorous-intensity physical activity in youth: The International Children's Accelerometry Database

    Directory of Open Access Journals (Sweden)

    Kirsten Corder

    2016-12-01

    Age-related declines in vigorous-intensity activity during youth appear relatively greater than those of moderate activity. However, due to a higher baseline, absolute moderate-intensity activity decreases more than vigorous. Overweight/obese individuals, girls, and North Americans appear especially in need of vigorous-intensity activity promotion due to low levels at 5.0–5.9 y and larger negative annual differences.

  1. Physical activity and its related motivational attributes in adolescents with different BMI.

    Science.gov (United States)

    Hwang, J; Kim, Y H

    2013-03-01

    A number of obesity studies have been focused on identifying the relationships between socioeconomic status and physical activity involvement. In behavioral medicine, the limited data are available on obese people's physical activity and its related psychological predictors based on psychological theories. To identify the differences in physical activity and its related motivational attributes among normal weight, overweight, and obese adolescents and to find the effect of body mass index (BMI) and the Self-Determination Theory (SDT) constructs in predicting physical activity. One thousand seventy-one students ranging from seventh to ninth grades were randomly selected from three junior high schools in Seoul (359 normal weight students, 468 overweight students, and 244 obese students). A Korean version of Behavioral Regulation in Exercise Questionnaire-2 and Leisure Time Exercise Questionnaire were applied to measure the participants' motivational attributes and physical activity. Overweight and obese adolescents showed higher scores on amotivation and externally motivated regulations for physical activity than their normal weight counterparts. Internal regulation was more significant for physical activity in normal weight adolescent. However, there was no difference in physical activity among the three groups. Additionally, the findings identified that BMI and the SDT constructs were significant to explain physical activity. This study offers fundamental knowledge in gaining a clearer understanding of the types of motivation most likely to contribute to the initiation and promotion of physical activity in overweight and obese adolescents.

  2. Using Active Learning to Identify Health Information Technology Related Patient Safety Events.

    Science.gov (United States)

    Fong, Allan; Howe, Jessica L; Adams, Katharine T; Ratwani, Raj M

    2017-01-18

    The widespread adoption of health information technology (HIT) has led to new patient safety hazards that are often difficult to identify. Patient safety event reports, which are self-reported descriptions of safety hazards, provide one view of potential HIT-related safety events. However, identifying HIT-related reports can be challenging as they are often categorized under other more predominate clinical categories. This challenge of identifying HIT-related reports is exacerbated by the increasing number and complexity of reports which pose challenges to human annotators that must manually review reports. In this paper, we apply active learning techniques to support classification of patient safety event reports as HIT-related. We evaluated different strategies and demonstrated a 30% increase in average precision of a confirmatory sampling strategy over a baseline no active learning approach after 10 learning iterations.

  3. The functional organization of trial-related activity in lexical processing after early left hemispheric brain lesions: An event-related fMRI study.

    Science.gov (United States)

    Fair, Damien A; Choi, Alexander H; Dosenbach, Yannic B L; Coalson, Rebecca S; Miezin, Francis M; Petersen, Steven E; Schlaggar, Bradley L

    2010-08-01

    Children with congenital left hemisphere damage due to perinatal stroke are capable of acquiring relatively normal language functions despite experiencing a cortical insult that in adults often leads to devastating lifetime disabilities. Although this observed phenomenon is accepted, its neurobiological mechanisms are not well characterized. In this paper we examined the functional neuroanatomy of lexical processing in 13 children/adolescents with perinatal left hemispheric damage. In contrast to many previous perinatal infarct fMRI studies, we used an event-related design, which allowed us to isolate trial-related activity and examine correct and error trials separately. Using both group and single subject analysis techniques we attempt to address several methodological factors that may contribute to some discrepancies in the perinatal lesion literature. These methodological factors include making direct statistical comparisons, using common stereotactic space, using both single subject and group analyses, and accounting for performance differences. Our group analysis, investigating correct trial-related activity (separately from error trials), showed very few statistical differences in the non-involved right hemisphere between patients and performance matched controls. The single subject analysis revealed atypical regional activation patterns in several patients; however, the location of these regions identified in individual patients often varied across subjects. These results are consistent with the idea that alternative functional organization of trial-related activity after left hemisphere lesions is in large part unique to the individual. In addition, reported differences between results obtained with event-related designs and blocked designs may suggest diverging organizing principles for sustained and trial-related activity after early childhood brain injuries. 2009 Elsevier Inc. All rights reserved.

  4. Flow cytometry and integrated imaging

    Directory of Open Access Journals (Sweden)

    V. Kachel

    2000-06-01

    Full Text Available It is a serious problem to relate the results of a flow cytometric analysis of a marine sample to different species. Images of particles selectively triggered by the flow cytometric analysis and picked out from the flowing stream give a valuable additional information on the analyzed organisms. The technical principles and problems of triggered imaging in flow are discussed, as well as the positioning of the particles in the plane of focus, freezing the motion of the quickly moving objects and what kinds of light sources are suitable for pulsed illumination. The images have to be stored either by film or electronically. The features of camera targets and the memory requirements for storing the image data and the conditions for the triggering device are shown. A brief explanation of the features of three realized flow cytometric imaging (FCI systems is given: the Macro Flow Planktometer built within the EUROMAR MAROPT project, the Imaging Module of the European Plankton Analysis System, supported by the MAST II EurOPA project and the most recently developed FLUVO VI universal flow cytometer including HBO 100- and laser excitation for fluorescence and scatter, Coulter sizing as well as bright field and and phase contrast FCI.

  5. Altered mucosal DNA methylation in parallel with highly active Helicobacter pylori-related gastritis.

    Science.gov (United States)

    Yoshida, Takeichi; Kato, Jun; Maekita, Takao; Yamashita, Satoshi; Enomoto, Shotaro; Ando, Takayuki; Niwa, Tohru; Deguchi, Hisanobu; Ueda, Kazuki; Inoue, Izumi; Iguchi, Mikitaka; Tamai, Hideyuki; Ushijima, Toshikazu; Ichinose, Masao

    2013-10-01

    Chronic inflammation triggered by Helicobacter pylori causes altered DNA methylation in stomach mucosae, which is deeply involved in gastric carcinogenesis. This study aimed to elucidate the correlation between altered mucosal DNA methylation levels and activity of H. pylori-related gastritis, because inflammatory activity shows particular correlations with the development of diffuse-type cancer. Methylation levels in stomach mucosae of 78 healthy volunteers were determined by real-time methylation-specific PCR or bisulfite pyrosequencing. Examined loci were the promoter CpG islands of six genes (FLNc, HAND1, THBD, p41ARC, HRASLS, and LOX) and the CpG sites of non-coding repetitive elements (Alu and Satα) that are reportedly altered by H. pylori infection. Activity of H. pylori-related gastritis was evaluated using two serum markers: H. pylori antibody titer and pepsinogen II. Methylation levels of the six CpG islands were consistently increased, and those of the two repetitive elements were consistently decreased in a stepwise manner with the activity of gastric inflammation as represented by serum marker levels. Each serum marker level was well correlated with the overall DNA methylation status of stomach mucosa, and these two serologic markers were additive in the detection of the mucosa with severely altered DNA methylation. Alteration in mucosal DNA methylation level was closely correlated with activity of H. pylori-related gastritis as evaluated by serum markers. The observed correlation between altered DNA methylation levels and activity of H. pylori-related gastritis appears to be one of the relevant molecular mechanisms underlying the development of diffuse-type cancer.

  6. Cerebral Activations Related to Ballistic, Stepwise Interrupted and Gradually Modulated Movements in Parkinson Patients

    Science.gov (United States)

    Toxopeus, Carolien M.; Maurits, Natasha M.; Valsan, Gopal; Conway, Bernard A.; Leenders, Klaus L.; de Jong, Bauke M.

    2012-01-01

    Patients with Parkinson’s disease (PD) experience impaired initiation and inhibition of movements such as difficulty to start/stop walking. At single-joint level this is accompanied by reduced inhibition of antagonist muscle activity. While normal basal ganglia (BG) contributions to motor control include selecting appropriate muscles by inhibiting others, it is unclear how PD-related changes in BG function cause impaired movement initiation and inhibition at single-joint level. To further elucidate these changes we studied 4 right-hand movement tasks with fMRI, by dissociating activations related to abrupt movement initiation, inhibition and gradual movement modulation. Initiation and inhibition were inferred from ballistic and stepwise interrupted movement, respectively, while smooth wrist circumduction enabled the assessment of gradually modulated movement. Task-related activations were compared between PD patients (N = 12) and healthy subjects (N = 18). In healthy subjects, movement initiation was characterized by antero-ventral striatum, substantia nigra (SN) and premotor activations while inhibition was dominated by subthalamic nucleus (STN) and pallidal activations, in line with the known role of these areas in simple movement. Gradual movement mainly involved antero-dorsal putamen and pallidum. Compared to healthy subjects, patients showed reduced striatal/SN and increased pallidal activation for initiation, whereas for inhibition STN activation was reduced and striatal-thalamo-cortical activation increased. For gradual movement patients showed reduced pallidal and increased thalamo-cortical activation. We conclude that PD-related changes during movement initiation fit the (rather static) model of alterations in direct and indirect BG pathways. Reduced STN activation and regional cortical increased activation in PD during inhibition and gradual movement modulation are better explained by a dynamic model that also takes into account enhanced

  7. Cerebral activations related to ballistic, stepwise interrupted and gradually modulated movements in Parkinson patients.

    Directory of Open Access Journals (Sweden)

    Carolien M Toxopeus

    Full Text Available Patients with Parkinson's disease (PD experience impaired initiation and inhibition of movements such as difficulty to start/stop walking. At single-joint level this is accompanied by reduced inhibition of antagonist muscle activity. While normal basal ganglia (BG contributions to motor control include selecting appropriate muscles by inhibiting others, it is unclear how PD-related changes in BG function cause impaired movement initiation and inhibition at single-joint level. To further elucidate these changes we studied 4 right-hand movement tasks with fMRI, by dissociating activations related to abrupt movement initiation, inhibition and gradual movement modulation. Initiation and inhibition were inferred from ballistic and stepwise interrupted movement, respectively, while smooth wrist circumduction enabled the assessment of gradually modulated movement. Task-related activations were compared between PD patients (N = 12 and healthy subjects (N = 18. In healthy subjects, movement initiation was characterized by antero-ventral striatum, substantia nigra (SN and premotor activations while inhibition was dominated by subthalamic nucleus (STN and pallidal activations, in line with the known role of these areas in simple movement. Gradual movement mainly involved antero-dorsal putamen and pallidum. Compared to healthy subjects, patients showed reduced striatal/SN and increased pallidal activation for initiation, whereas for inhibition STN activation was reduced and striatal-thalamo-cortical activation increased. For gradual movement patients showed reduced pallidal and increased thalamo-cortical activation. We conclude that PD-related changes during movement initiation fit the (rather static model of alterations in direct and indirect BG pathways. Reduced STN activation and regional cortical increased activation in PD during inhibition and gradual movement modulation are better explained by a dynamic model that also takes into account

  8. Brain activity related to working memory for temporal order and object information.

    Science.gov (United States)

    Roberts, Brooke M; Libby, Laura A; Inhoff, Marika C; Ranganath, Charan

    2017-06-08

    Maintaining items in an appropriate sequence is important for many daily activities; however, remarkably little is known about the neural basis of human temporal working memory. Prior work suggests that the prefrontal cortex (PFC) and medial temporal lobe (MTL), including the hippocampus, play a role in representing information about temporal order. The involvement of these areas in successful temporal working memory, however, is less clear. Additionally, it is unknown whether regions in the PFC and MTL support temporal working memory across different timescales, or at coarse or fine levels of temporal detail. To address these questions, participants were scanned while completing 3 working memory task conditions (Group, Position and Item) that were matched in terms of difficulty and the number of items to be actively maintained. Group and Position trials probed temporal working memory processes, requiring the maintenance of hierarchically organized coarse and fine temporal information, respectively. To isolate activation related to temporal working memory, Group and Position trials were contrasted against Item trials, which required detailed working memory maintenance of visual objects. Results revealed that working memory encoding and maintenance of temporal information relative to visual information was associated with increased activation in dorsolateral PFC (DLPFC), and perirhinal cortex (PRC). In contrast, maintenance of visual details relative to temporal information was characterized by greater activation of parahippocampal cortex (PHC), medial and anterior PFC, and retrosplenial cortex. In the hippocampus, a dissociation along the longitudinal axis was observed such that the anterior hippocampus was more active for working memory encoding and maintenance of visual detail information relative to temporal information, whereas the posterior hippocampus displayed the opposite effect. Posterior parietal cortex was the only region to show sensitivity to temporal

  9. Error-related negativity varies with the activation of gender stereotypes.

    Science.gov (United States)

    Ma, Qingguo; Shu, Liangchao; Wang, Xiaoyi; Dai, Shenyi; Che, Hongmin

    2008-09-19

    The error-related negativity (ERN) was suggested to reflect the response-performance monitoring process. The purpose of this study is to investigate how the activation of gender stereotypes influences the ERN. Twenty-eight male participants were asked to complete a tool or kitchenware identification task. The prime stimulus is a picture of a male or female face and the target stimulus is either a kitchen utensil or a hand tool. The ERN amplitude on male-kitchenware trials is significantly larger than that on female-kitchenware trials, which reveals the low-level, automatic activation of gender stereotypes. The ERN that was elicited in this task has two sources--operation errors and the conflict between the gender stereotype activation and the non-prejudice beliefs. And the gender stereotype activation may be the key factor leading to this difference of ERN. In other words, the stereotype activation in this experimental paradigm may be indexed by the ERN.

  10. Psychoacoustic Tinnitus Loudness and Tinnitus-Related Distress Show Different Associations with Oscillatory Brain Activity

    Science.gov (United States)

    Balkenhol, Tobias; Wallhäusser-Franke, Elisabeth; Delb, Wolfgang

    2013-01-01

    Background The phantom auditory perception of subjective tinnitus is associated with aberrant brain activity as evidenced by magneto- and electroencephalographic studies. We tested the hypotheses (1) that psychoacoustically measured tinnitus loudness is related to gamma oscillatory band power, and (2) that tinnitus loudness and tinnitus-related distress are related to distinct brain activity patterns as suggested by the distinction between loudness and distress experienced by tinnitus patients. Furthermore, we explored (3) how hearing impairment, minimum masking level, and (4) psychological comorbidities are related to spontaneous oscillatory brain activity in tinnitus patients. Methods and Findings Resting state oscillatory brain activity recorded electroencephalographically from 46 male tinnitus patients showed a positive correlation between gamma band oscillations and psychoacoustic tinnitus loudness determined with the reconstructed tinnitus sound, but not with the other psychoacoustic loudness measures that were used. Tinnitus-related distress did also correlate with delta band activity, but at electrode positions different from those associated with tinnitus loudness. Furthermore, highly distressed tinnitus patients exhibited a higher level of theta band activity. Moreover, mean hearing loss between 0.125 kHz and 16 kHz was associated with a decrease in gamma activity, whereas minimum masking levels correlated positively with delta band power. In contrast, psychological comorbidities did not express significant correlations with oscillatory brain activity. Conclusion Different clinically relevant tinnitus characteristics show distinctive associations with spontaneous brain oscillatory power. Results support hypothesis (1), but exclusively for the tinnitus loudness derived from matching to the reconstructed tinnitus sound. This suggests to preferably use the reconstructed tinnitus spectrum to determine psychoacoustic tinnitus loudness. Results also support

  11. 2016 Workplace and Gender Relations Survey of Active Duty Members: Frequently Asked Questions

    Science.gov (United States)

    2017-05-01

    outstanding research that has had a clear impact on improving policy decisions practice or discourse, either in the public or private sectors .” 6. What...2017 2016 Workplace and Gender Relations Survey of Active Duty Members 433 | OPA Frequently Asked Questions 2016 Workplace and Gender Relations...OPA), has been conducting surveys of gender issues for the active duty military since 1988. RSSC uses scientific state of the art statistical

  12. Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology.

    Science.gov (United States)

    Salamone, John D; Yohn, Samantha E; López-Cruz, Laura; San Miguel, Noemí; Correa, Mercè

    2016-05-01

    Motivation has been defined as the process that allows organisms to regulate their internal and external environment, and control the probability, proximity and availability of stimuli. As such, motivation is a complex process that is critical for survival, which involves multiple behavioural functions mediated by a number of interacting neural circuits. Classical theories of motivation suggest that there are both directional and activational aspects of motivation, and activational aspects (i.e. speed and vigour of both the instigation and persistence of behaviour) are critical for enabling organisms to overcome work-related obstacles or constraints that separate them from significant stimuli. The present review discusses the role of brain dopamine and related circuits in behavioural activation, exertion of effort in instrumental behaviour, and effort-related decision-making, based upon both animal and human studies. Impairments in behavioural activation and effort-related aspects of motivation are associated with psychiatric symptoms such as anergia, fatigue, lassitude and psychomotor retardation, which cross multiple pathologies, including depression, schizophrenia, and Parkinson's disease. Therefore, this review also attempts to provide an interdisciplinary approach that integrates findings from basic behavioural neuroscience, behavioural economics, clinical neuropsychology, psychiatry, and neurology, to provide a coherent framework for future research and theory in this critical field. Although dopamine systems are a critical part of the brain circuitry regulating behavioural activation, exertion of effort, and effort-related decision-making, mesolimbic dopamine is only one part of a distributed circuitry that includes multiple neurotransmitters and brain areas. Overall, there is a striking similarity between the brain areas involved in behavioural activation and effort-related processes in rodents and in humans. Animal models of effort-related decision

  13. Modeling the fine fragmentation following the triggering stage of a vapor explosion; Modelisation de la fragmentaton fine lors de la phase de declenchement d`une explosion de vapeur

    Energy Technology Data Exchange (ETDEWEB)

    Darbord, I [CEA Grenoble, 38 (France). Service d` Etudes et de Modelisation Thermohydraulique

    1997-06-11

    In the frame of PWR severe accidents, where the core melt, this thesis studies one of the stages of an FCI (fuel coolant interaction) or vapor explosion. An FCI is a rapid evaporation of a coolant when it comes into contact with a hot liquid. More precisely, the subject of this study is the triggering stage of the FCI, when a fuel drop of diameter around one centimeter breaks up into many fragments, diameter of which is around a hundred micrometers. The model describes the cyclic collapse and growth of a vapor bubble around the fuel droplet and its fragmentation. The main features of the model are: - the destabilization of the film or the vapor bubble due to the growth of Rayleigh-Taylor instabilities (those form coolant jets that contact the fuel surface); - The mechanisms of fragmentation, following the contacts (in the case of entrapment of a certain amount of coolant in the fuel, the entrapped coolant evaporates violently after it has been heated to the homogeneous nucleation temperature); - the transient heat transfer from the fragments to the coolant and the elevated vapor production, which leads to an important expansion of the bubble (about this point, the cooling of the fragments has been described by a transient heat transfer coefficient linked to nucleate boiling). The results of the model show good agreement with experimental data. (Author) 68 refs.

  14. Modeling the fine fragmentation following the triggering stage of a vapor explosion

    International Nuclear Information System (INIS)

    Darbord, I.

    1997-01-01

    In the frame of PWR severe accidents, where the core melt, this thesis studies one of the stages of an FCI (fuel coolant interaction) or vapor explosion. An FCI is a rapid evaporation of a coolant when it comes into contact with a hot liquid. More precisely, the subject of this study is the triggering stage of the FCI, when a fuel drop of diameter around one centimeter breaks up into many fragments, diameter of which is around a hundred micrometers. The model describes the cyclic collapse and growth of a vapor bubble around the fuel droplet and its fragmentation. The main features of the model are: - the destabilization of the film or the vapor bubble due to the growth of Rayleigh-Taylor instabilities (those form coolant jets that contact the fuel surface); - The mechanisms of fragmentation, following the contacts (in the case of entrapment of a certain amount of coolant in the fuel, the entrapped coolant evaporates violently after it has been heated to the homogeneous nucleation temperature); - the transient heat transfer from the fragments to the coolant and the elevated vapor production, which leads to an important expansion of the bubble (about this point, the cooling of the fragments has been described by a transient heat transfer coefficient linked to nucleate boiling). The results of the model show good agreement with experimental data. (Author)

  15. Socioeconomic position and work, travel, and recreation-related physical activity in Japanese adults: a cross-sectional study.

    Science.gov (United States)

    Matsushita, Munehiro; Harada, Kazuhiro; Arao, Takashi

    2015-09-18

    The aim of this study was to examine the association between socioeconomic position and the domains of physical activity connected with work, travel, and recreation in Japanese adults. A total of 3269 subjects, 1651 men (mean ± standard deviation; 44.2 ± 8.1 years) and 1618 women (44.1 ± 8.1 years), responded to an Internet-based cross-sectional survey. Data on socioeconomic (household income, educational level) and demographic variables (age, size of household, and household motor vehicles) were obtained. To examine the associations between socioeconomic position and physical activity, logistic regression analysis was used to calculate the odds ratio (OR) and confidence interval (CI) for "active" domains of physical activity. Men with a household income of ≥ 7 million yen had significantly lower work-related physical activity than the lowest income group (OR 0.51; 95 % CI, 0.35-0.75), but significantly greater travel-related (OR 1.37; 1.02-1.85), recreational (OR 2.00; 1.46-2.73) and total physical activity (OR 1.56; 1.17-2.08). Women with a household income of ≥ 7 million yen had significantly greater recreational physical activity (OR 1.43; 1.01-2.04) than the lowest income group. Their total physical activity was borderline significant, with slightly more activity in the high-income group (OR 1.36; 1.00-1.84), but no significant differences for work- and travel-related physical activity. Men with higher educational level (4-year college or higher degree) had significantly lower work-related (OR 0.62; 0.46-0.82), and greater travel-related physical activity (OR 1.33; 1.04-1.71) than the lowest educated group, but there were no significant differences in recreational and total physical activity. Women with a 4-year college or higher degree had significantly greater travel-related physical activity than the lowest educated group (OR 1.49; 1.12-1.97), but there were no significant differences in any other physical activity. There was no relation between

  16. Qualification and competence in workers with limitations acquired in work related activity

    Directory of Open Access Journals (Sweden)

    Rosa Liliana Sbriller

    2017-12-01

    Full Text Available Introduction: The present research is based on the posture of critical occupational therapy and analyzes the concept of occupational skills required in the current job market, and its application in processes of work exclusion - inclusion in people with limitations acquired due to work related activities. Objective: Describe and analyze the concept of labor competencies within the transformation of the globalized occupational world, and analyze the impact of the required skills in the processes of exclusion - inclusion of people with limitations acquired due to work related activities. Method: Qualitative research. Technique: Documentary analysis and literary review. Results: Consider skills as construction in social action promotes debate within the field of occupational therapy with regard to professional intervention, expanding opportunities for job inclusion of people limitations acquired due to work related activities within the context of economic exclusion from the globalized labor market. Conclusion: Understanding the problem and it is current implications, helps to question praxis of occupational therapy and promotes the basis for an empirical investigation.

  17. Improving student learning and views of physics in a large enrollment introductory physics class

    Science.gov (United States)

    Salehzadeh Einabad, Omid

    Introductory physics courses often serve as gatekeepers for many scientific and engineering programs and, increasingly, colleges are relying on large, lecture formats for these courses. Many students, however, leave having learned very little physics and with poor views of the subject. In interactive engagement (IE), classroom activities encourage students to engage with each other and with physics concepts and to be actively involved in their own learning. These methods have been shown to be effective in introductory physics classes with small group recitations. This study examined student learning and views of physics in a large enrollment course that included IE methods with no separate, small-group recitations. In this study, a large, lecture-based course included activities that had students explaining their reasoning both verbally and in writing, revise their ideas about physics concepts, and apply their reasoning to various problems. The questions addressed were: (a) What do students learn about physics concepts and how does student learning in this course compare to that reported in the literature for students in a traditional course?, (b) Do students' views of physics change and how do students' views of physics compare to that reported in the literature for students in a traditional course?, and (c) Which of the instructional strategies contribute to student learning in this course? Data included: pre-post administration of the Force Concept Inventory (FCI), classroom exams during the term, pre-post administration of the Colorado Learning Attitudes About Science Survey (CLASS), and student work, interviews, and open-ended surveys. The average normalized gain (=0.32) on the FCI falls within the medium-gain range as reported in the physics education literature, even though the average pre-test score was very low (30%) and this was the instructor's first implementation of IE methods. Students' views of physics remained relatively unchanged by instruction

  18. Climate change and related activities

    International Nuclear Information System (INIS)

    1992-01-01

    The production and consumption of energy contributes to the concentration of greenhouse gases in the atmosphere and is the focus of other environmental concerns as well. Yet the use of energy contributes to worldwide economic growth and development. If we are to achieve environmentally sound economic growth, we must develop and deploy energy technologies that contribute to global stewardship. The Department of Energy carries out an aggressive scientific research program to address some of the key uncertainties associated with the climate change issue. Of course, research simply to study the science of global climate change is not enough. At the heart of any regime of cost-effective actions to address the possibility of global climate change will be a panoply of new technologies-technologies both to provide the services we demand and to use energy more efficiently than in the past. These, too, are important areas of responsibility for the Department. This report is a brief description of the Department's activities in scientific research, technology development, policy studies, and international cooperation that are directly related to or have some bearing on the issue of global climate change

  19. [The association between socioeconomic indicators andadolescents'physical activity and health-related fitness].

    Science.gov (United States)

    Constantino-Coledam, Diogo H; Ferraiol, Philippe Fanelli; Arruda, Gustavo Aires de; Pires-Júnior, Raymundo; Teixeira, Marcio; Greca, João Paulo de Aguiar; Oliveira, Arli Ramos de

    2013-01-01

    This study was aimed at analysing the association between socioeconomic indicators and adolescents' physical activity and health-related fitness. The study involved 716 adolescents from both genders whose age ranged from 10 to 18 years-old (46.8% male) who answered a questionnaire for estimating their habitual physical activity, socioeconomic status; two health-related physical fitness tests were also performed. The socioeconomic indicators analysed concerned their parents' educational level and the number of bathrooms, TVs, cars, housemaids, refrigerators and freezers in their homes. A positive association was found between paternal education (PR=1.61 (range 1.27-2.10) and 1.41 (1.10-1.83)) and housemaids (PR=1.97 (1.04-3.81) and 1.92 (1.05-3.52)) with recommended physical activity and leisure time physical activity, respectively. The number of cars (PR=1.48: 1.02-2.19) and freezers (PR=1.88: 1.12-3.18) was positively associated with leisure time physical activity and the number of TVs negatively so (PR=0.75: 0.63-0.89). The number of TVs (PR=0.80: 0.67-0.96) and cars (PR=0.70: 0.55-0.89) was negatively associated with cardiorespiratory fitness whilst paternal education (PR=1.17: 1.00-1.37) and the number of bathrooms in the home (PR=1.25: 1.02-1.54) were positively associated with muscular strength. Physical activity and health-related physical fitness were associated with socioeconomic status. However, such association depended on the socioeconomic indicator being analysed. Caution should be taken when analysing studies which use different socioeconomic indicators.

  20. A single sphere film boiling model for trigger ability and explosion potential

    International Nuclear Information System (INIS)

    Park, Ik Kyu; Kim, Jong Hwan; Hong, Seong Ho; Hong, Seong Wan

    2012-01-01

    The main causes for the controversy about the corium explosiveness are the hydrogen effect, large voided mixture, material property, poor triggering event (wrong position, weak triggering, wrong time), and low superheat due to a high melting temperature. It has been suggested that a steam explosion of the corium/water system must be suppressed due to the physical properties of corium such as high temperature, high density, multicomponent oxide melt, and low thermal conductivity. It was also claimed that the magnitude of the effect on the FCI results of corium/water systems is on the order of higher density, higher temperature, and non eutectic composition. This concept of a material effect is supported to some degree by parametric experimental results. However, the parametric results between the steam explosion pressure and the material compositions do not directly provide an understanding of the mechanism for the material difference affecting a steam explosion process, even though the sensitivity results can reveal the trends of some parameters affecting the FCI results. This concept of a material effect is supported to some degree by parametric experimental results. The parametric tests themselves also provide us with information on the effect of each initial parameter on a steam explosion. However, sensitivity studies between the steam explosion pressure and the initial value of a parameter do not directly provide an understanding of the steam explosion process. Handling the explosion res sure and initial condition without a mixing could not contribute to a code development process. We need a certain parameter for representing mixing, but we cannot measure it during the FCI tests. The particle size distribution collected after the FCI tests can be a good indicator for explaining a mixing process. In this paper, TROI tests were analyzed in view of a particle size response for various types of fuel coolant explosions. The heat losses and remnants were calculated

  1. The effects of modeling instruction on high school physics academic achievement

    Science.gov (United States)

    Wright, Tiffanie L.

    The purpose of this study was to explore whether Modeling Instruction, compared to traditional lecturing, is an effective instructional method to promote academic achievement in selected high school physics classes at a rural middle Tennessee high school. This study used an ex post facto , quasi-experimental research methodology. The independent variables in this study were the instructional methods of teaching. The treatment variable was Modeling Instruction and the control variable was traditional lecture instruction. The Treatment Group consisted of participants in Physical World Concepts who received Modeling Instruction. The Control Group consisted of participants in Physical Science who received traditional lecture instruction. The dependent variable was gains scores on the Force Concepts Inventory (FCI). The participants for this study were 133 students each in both the Treatment and Control Groups (n = 266), who attended a public, high school in rural middle Tennessee. The participants were administered the Force Concepts Inventory (FCI) prior to being taught the mechanics of physics. The FCI data were entered into the computer-based Statistical Package for the Social Science (SPSS). Two independent samples t-tests were conducted to answer the research questions. There was a statistically significant difference between the treatment and control groups concerning the instructional method. Modeling Instructional methods were found to be effective in increasing the academic achievement of students in high school physics. There was no statistically significant difference between FCI gains scores for gender. Gender was found to have no effect on the academic achievement of students in high school physics classes. However, even though there was not a statistically significant difference, female students' gains scores were higher than male students' gains scores when Modeling Instructional methods of teaching were used. Based on these findings, it is recommended

  2. Gritty people try harder: grit and effort-related cardiac autonomic activity during an active coping challenge.

    Science.gov (United States)

    Silvia, Paul J; Eddington, Kari M; Beaty, Roger E; Nusbaum, Emily C; Kwapil, Thomas R

    2013-05-01

    Grit, a recently proposed personality trait associated with persistence for long-range goals, predicts achievement in a wide range of important life outcomes. Using motivational intensity theory, the present research examined the physiological underpinnings of grit during an active coping task. Forty young adults completed the Short Grit Scale and worked on a self-paced mental effort task. Effort-related autonomic nervous system (ANS) activity was assessed using impedance cardiography, which yielded measures of sympathetic activity (pre-ejection period; PEP) and parasympathetic activity (respiratory sinus arrhythmia; RSA). Multilevel models revealed that people high on the Perseverance of Effort subscale showed autonomic coactivation: both PEP and RSA became stronger during the task, reflecting higher activity of both ANS divisions. The Consistency of Interest subscale, in contrast, predicted only weaker sympathetic activity (slower PEP). Taken together, the findings illuminate autonomic processes associated with how "gritty" people pursue goals, and they suggest that more attention should be paid to the facets' distinct effects. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Reward-Related Ventral Striatum Activity Buffers against the Experience of Depressive Symptoms Associated with Sleep Disturbances.

    Science.gov (United States)

    Avinun, Reut; Nevo, Adam; Knodt, Annchen R; Elliott, Maxwell L; Radtke, Spenser R; Brigidi, Bartholomew D; Hariri, Ahmad R

    2017-10-04

    Sleep disturbances represent one risk factor for depression. Reward-related brain function, particularly the activity of the ventral striatum (VS), has been identified as a potential buffer against stress-related depression. We were therefore interested in testing whether reward-related VS activity would moderate the effect of sleep disturbances on depression in a large cohort of young adults. Data were available from 1129 university students (mean age 19.71 ± 1.25 years; 637 women) who completed a reward-related functional MRI task to assay VS activity and provided self-reports of sleep using the Pittsburgh Sleep Quality Index and symptoms of depression using a summation of the General Distress/Depression and Anhedonic Depression subscales of the Mood and Anxiety Symptoms Questionnaire-short form. Analyses revealed that as VS activity increased the association between sleep disturbances and depressive symptoms decreased. The interaction between sleep disturbances and VS activity was robust to the inclusion of sex, age, race/ethnicity, past or present clinical disorder, early and recent life stress, and anxiety symptoms, as well as the interactions between VS activity and early or recent life stress as covariates. We provide initial evidence that high reward-related VS activity may buffer against depressive symptoms associated with poor sleep. Our analyses help advance an emerging literature supporting the importance of individual differences in reward-related brain function as a potential biomarker of relative risk for depression. SIGNIFICANCE STATEMENT Sleep disturbances are a common risk factor for depression. An emerging literature suggests that reward-related activity of the ventral striatum (VS), a brain region critical for motivation and goal-directed behavior, may buffer against the effect of negative experiences on the development of depression. Using data from a large sample of 1129 university students we demonstrate that as reward-related VS activity

  4. Brain activity related to phonation in young patients with adductor spasmodic dysphonia.

    Science.gov (United States)

    Kiyuna, Asanori; Maeda, Hiroyuki; Higa, Asano; Shingaki, Kouta; Uehara, Takayuki; Suzuki, Mikio

    2014-06-01

    This study investigated the brain activities during phonation of young patients with adductor spasmodic dysphonia (ADSD) of relatively short disease duration (<10 years). Six subjects with ADSD of short duration (mean age: 24. 3 years; mean disease duration: 41 months) and six healthy controls (mean age: 30.8 years) underwent functional magnetic resonance imaging (fMRI) using a sparse sampling method to identify brain activity during vowel phonation (/i:/). Intragroup and intergroup analyses were performed using statistical parametric mapping software. Areas of activation in the ADSD and control groups were similar to those reported previously for vowel phonation. All of the activated areas were observed bilaterally and symmetrically. Intergroup analysis revealed higher brain activities in the SD group in the auditory-related areas (Brodmann's areas [BA] 40, 41), motor speech areas (BA44, 45), bilateral insula (BA13), bilateral cerebellum, and middle frontal gyrus (BA46). Areas with lower activation were in the left primary sensory area (BA1-3) and bilateral subcortical nucleus (putamen and globus pallidus). The auditory cortical responses observed may reflect that young ADSD patients control their voice by use of the motor speech area, insula, inferior parietal cortex, and cerebellum. Neural activity in the primary sensory area and basal ganglia may affect the voice symptoms of young ADSD patients with short disease duration. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  5. Gender-related differences in lateralization of hippocampal activation and cognitive strategy.

    Science.gov (United States)

    Frings, Lars; Wagner, Kathrin; Unterrainer, Josef; Spreer, Joachim; Halsband, Ulrike; Schulze-Bonhage, Andreas

    2006-03-20

    Gender-related differences in brain activation patterns and their lateralization associated with cognitive functions have been reported in the field of language, emotion, and working memory. Differences have been hypothesized to be due to different cognitive strategies. The aim of the present study was to test whether lateralization of brain activation in the hippocampi during memory processing differs between the sexes. We acquired functional magnetic resonance imaging data from healthy female and male study participants performing a spatial memory task and quantitatively assessed the lateralization of hippocampal activation in each participant. Hippocampal activation was significantly more left lateralized in women, and more right lateralized in men. Correspondingly, women rated their strategy as being more verbal than men did.

  6. Longitudinal person-related determinants of physical activity in young adults.

    NARCIS (Netherlands)

    Uijtdewilligen, L.; Twisk, J.W.R.; Chinapaw, M.J.M.; Koppes, L.L.J.; Mechelen, W. van; Singh, A.S.

    2014-01-01

    Purpose: This study aimed to examine the longitudinal associations of person-related factors with physical activity (PA) behavior in young adults. Methods: We analyzed longitudinal self-reported time spent in moderate-intensity PA (MPA; 4–7 METs) and vigorous-intensity PA (VPA; >7 METs) from 499

  7. Longitudinal Person-Related Determinants of Physical Activity in Young Adults

    NARCIS (Netherlands)

    Uijtdewilligen, L.; Twisk, J.W.R.; Chin A Paw, M.J.M.; Koppes, L.L.J.; van Mechelen, W.; Singh, A.S.

    2014-01-01

    Purpose: This study aimed to examine the longitudinal associations of person-related factors with physical activity (PA) behavior in young adults. Methods: We analyzed longitudinal self-reported time spent in moderate-intensity PA (MPA; 4-7 METs) and vigorous-intensity PA (VPA; >7 METs) from 499

  8. Longitudinal person-related determinants of physical activity in young adults

    NARCIS (Netherlands)

    Uijtdewilligen, L.; Twisk, J.W.R.; Chinapaw, M.J.M.; Koppes, L.L.J.; Mechelen, W. van; Singh, A.S.

    2014-01-01

    Purpose: This study aimed to examine the longitudinal associations of person-related factors with physical activity (PA) behavior in young adults. Methods: We analyzed longitudinal self-reported time spent in moderate-intensity PA (MPA; 4-7 METs) and vigorous-intensity PA (VPA; >7 METs) from 499

  9. Update on the SDTP Sponsored Fukushima Daiichi Related Assesment Activities

    International Nuclear Information System (INIS)

    Allison, Chris

    2014-01-01

    Following the accident at Fukushima Daiichi, Innovative Systems Software and several other members of an international software development and training group (SDTP) started an assessment of the possible core/vessel damage states of Units 1-3. This assessment, using a reference RELAP/SCDAPSIM Laguna Verde BWR model developed by CNSNS, the Mexican nuclear regulatory body, was presented initially to the IAEA emergency response team for Fukushima in March of 2011. Our assessment for the IAEA indicated that significant fuel melting, fuel slumping, and lower head failure was likely for Units 1 and 3. The results for Unit 2 were inconclusive because of the complex thermal hydraulic conditions at the time of likely fuel melting. Since that time the SDTP related assessment activities have continued on three main fronts: (a) continued analysis using our representative Laguna Verde model to determine the likely failure modes leading to an un-intentional depressurization of the vessel during a SBO in a BWR, (b) development of improved RELAP/SCDAPSIM models to treat the likely mode of lower core support structure melting and failure, and (c) design studies for proposed fuel melting and relocation experiments in Japan to support model development and cleanup related activities, The presentation gives a brief summary and discussion of these activities.

  10. Reward-related frontostriatal activity and smoking behavior among adolescents in treatment for smoking cessation.

    Science.gov (United States)

    Garrison, Kathleen A; Yip, Sarah W; Balodis, Iris M; Carroll, Kathleen M; Potenza, Marc N; Krishnan-Sarin, Suchitra

    2017-08-01

    Tobacco use is often initiated during adolescence and continued into adulthood despite desires to quit. A better understanding of the neural correlates of abstinence from smoking in adolescents may inform more effective smoking cessation interventions. Neural reward systems are implicated in tobacco use disorder, and adolescent smokers have shown reduced reward-related ventral striatal activation related to increased smoking. The current study evaluated nondrug reward anticipation in adolescent smokers using a monetary incentive delay task in fMRI pre- and post- smoking cessation treatment (n=14). This study tested how changes in neural responses to reward anticipation pre- to post-treatment were related to reduced smoking. An exploratory analysis in a larger sample of adolescents with only pre-treatment fMRI (n=28) evaluated how neural responses to reward anticipation were related to behavioral inhibition and behavioral activation scales. Adolescent smokers showed pre- to post-treatment increases in reward anticipation-related activity in the bilateral nucleus accumbens and insula, and medial prefrontal cortex, and greater increases in reward anticipation-related activity were correlated with larger percent days of smoking abstinence during treatment. These findings suggest that reduced smoking during smoking cessation treatment is associated with a "recovery of function" in frontostriatal responses to nondrug reward anticipation in adolescent smokers, although comparison with a developmental control group of adolescent nonsmokers is warranted. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. [Relation between physical activity, weight balance and breast cancer].

    Science.gov (United States)

    Maître, Carole

    2013-05-01

    Many epidemiologic studies, with a good methodology, support the evidence of the positive role of regular physical activity on primary and tertiary prevention of breast cancer on the risk of recurrence and mortality. This relation depends on the level of total energy expenditure by week, which helps balance weight on lifetime, an essential part of benefit. The beneficial effects of physical activity are linked to many interrelated additional mechanisms: in a short-term, contraction of skeletal muscles involves aerobic metabolism which utilizes glucose and amino acids like glutamine, improves insulin sensitivity and lowers plasma insulin; in a long-term, physical activity produces favorable changes in body composition, decreasing body fat and increasing lean mass. That is a key point to reduce the intake of energy substrates stimulating carcinogenesis, to improve insulin sensitivity, to change the ratio of leptin and adiponectin, to enhance cellular immunity and to block cellular pathways of cell proliferation and angiogenesis. Maintaining a healthy weight through regular physical activity well balanced with energy intake is it a goal for prevention of breast cancer. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  12. Relation of physical activity and self-esteem.

    Science.gov (United States)

    Bobbio, Andrea

    2009-04-01

    The aim of this study was to examine the relation between self-esteem appraisal and physical activity testing a convenience sample of 211 individuals, ages 19 to 35 years and selected from the general population after a brief structured interview. They were grouped by sport habits into three distinct groups named Athletes, Nonathletes, and Sedentary people, and then were examined for significant differences in self-esteem scores measured via the Heatherton and Polivy State Self-esteem Scale which assesses three correlated factors, respectively, Performance, Social, and Appearance. As hypothesized, self-esteem scores between-groups differences emerged for the Appearance factor only, and the Sedentary group scored comparatively lower than the other two groups.

  13. Combating Corruption Relates Money Laundering Activities in Indonesia: a Hope and Reality

    OpenAIRE

    Handoyo, Sigit

    2008-01-01

    Corruption in Indonesia has become a culture and systemic so that it could not be eradicated in the short period of time. As corruption is closely related to money laundering activities, it is not impossible that combating corruption also means combating money laun-dering activities. PPATK (Pusat Pengkajian dan Analisis Transaksi Keuangan) as the Indone-sia's FIU (Financial Intelligence Unit) has hard works to reveal those money laundering and corruptions activities. Beside its obstacles, PPA...

  14. The relation between instrumental musical activity and cognitive aging.

    Science.gov (United States)

    Hanna-Pladdy, Brenda; MacKay, Alicia

    2011-05-01

    Intensive repetitive musical practice can lead to bilateral cortical reorganization. However, whether musical sensorimotor and cognitive abilities transfer to nonmusical cognitive abilities that are maintained throughout the life span is unclear. In an attempt to identify modifiable lifestyle factors that may potentially enhance successful aging, we evaluated the association between musical instrumental participation and cognitive aging. Seventy older healthy adults (ages 60-83) varying in musical activity completed a comprehensive neuropsychological battery. The groups (nonmusicians, low and high activity musicians) were matched on age, education, history of physical exercise, while musicians were matched on age of instrumental acquisition and formal years of musical training. Musicians were classified in the low (1-9 years) or high (>10 years) activity group based on years of musical experience throughout their life span. The results of this preliminary study revealed that participants with at least 10 years of musical experience (high activity musicians) had better performance in nonverbal memory (η2 = .106), naming (η2 = .103), and executive processes (η2 = .131) in advanced age relative to nonmusicians. Several regression analyses evaluated how years of musical activity, age of acquisition, type of musical training, and other variables predicted cognitive performance. These correlational results suggest a strong predictive effect of high musical activity throughout the life span on preserved cognitive functioning in advanced age. A discussion of how musical participation may enhance cognitive aging is provided along with other alternative explanations.

  15. Factors related to rural young adolescents' participation in outdoor, noncompetitive physical activity.

    Science.gov (United States)

    Christiana, Richard W; Davis, Marsha; Wilson, Mark G; McCarty, Frances A; Green, Gary T

    2014-12-01

    Young adolescents who have little interest in participating in competitive team sports are at an increased risk for physical inactivity. Noncompetitive outdoor physical activity can provide young adolescents with increased opportunities to participate in physical activities that appeal to them and have positive health effects. The purpose of this study was to examine factors related to rural young adolescents' participation in noncompetitive outdoor physical activity to inform intervention design. Young adolescents aged 10 to 14 years old (N = 1,032) from 1 rural county completed a self-administered questionnaire assessing constructs from self-determination theory (SDT) and the theory of planned behavior (TPB) related to noncompetitive outdoor physical activity. Structural equation modeling was used to examine an integrated conceptual model of hypothesized relationships among constructs. The hypothesized conceptual model provided a good fit to the data with greater perceptions of autonomy support and self-determined motivation having statistically significant positive indirect effects on participation in noncompetitive outdoor physical activity mediated by the constructs of the TPB. All direct paths in the model were statistically significant; however, the direct effect of attitudes on intention was weak (.08) and self-determined motivation had no indirect effect on intention through attitudes (.03). Constructs of SDT and TPB should be accounted for by interventions targeting noncompetitive outdoor physical activity among young adolescents. More research is needed to determine young adolescents' preferences for noncompetitive and competitive physical activity and the potential influence that noncompetitive outdoor physical activity may have on total daily physical activity.

  16. Assessment of sedentary behaviors and transport-related activities by questionnaire: a validation study

    Directory of Open Access Journals (Sweden)

    Keitly Mensah

    2016-08-01

    Full Text Available Abstract Background Comprehensive assessment of sedentary behavior (SB and physical activity (PA, including transport-related activities (TRA, is required to design innovative PA promotion strategies. There are few validated instruments that simultaneously assess the different components of human movement according to their context of practice (e.g. work, transport, leisure. We examined test-retest reliability and validity of the Sedentary, Transportation and Activity Questionnaire (STAQ, a newly developed questionnaire dedicated to assessing context-specific SB, TRA and PA. Methods Ninety six subjects (51 women kept a contextualized activity-logbook and wore a hip accelerometer (Actigraph GT3X + TM for a 7-day or 14-day period, at the end of which they completed the STAQ. Activity-energy expenditure was measured in a subgroup of 45 subjects using the double labeled water (DLW method. Test-retest reliability was assessed using intra-class-coefficients (ICC in a subgroup of 32 subjects who filled the questionnaire twice one month apart. Accelerometry was annotated using the logbook to obtain total and context-specific objective estimates of SB. Spearman correlations, Bland-Altman plots and ICC were used to analyze validity with logbook, accelerometry and DLW data validity criteria. Results Test-retest reliability was fair for total sitting time (ICC = 0.52, good to excellent for work sitting time (ICC = 0.71, transport-related walking (ICC = 0.61 and car use (ICC = 0.67, and leisure screen-related SB (ICC = 0.64-0.79, but poor for total sitting time during leisure and transport-related contexts. For validity, compared to accelerometry, significant correlations were found for STAQ estimates of total (r = 0.54 and context-specific sitting times with stronger correlations for work sitting time (r = 0.88, and screen times (TV/DVD viewing: r = 0.46; other screens: r = 0.42 than for transport (r = 0.35 or

  17. Assessment of sedentary behaviors and transport-related activities by questionnaire: a validation study.

    Science.gov (United States)

    Mensah, Keitly; Maire, Aurélia; Oppert, Jean-Michel; Dugas, Julien; Charreire, Hélène; Weber, Christiane; Simon, Chantal; Nazare, Julie-Anne

    2016-08-09

    Comprehensive assessment of sedentary behavior (SB) and physical activity (PA), including transport-related activities (TRA), is required to design innovative PA promotion strategies. There are few validated instruments that simultaneously assess the different components of human movement according to their context of practice (e.g. work, transport, leisure). We examined test-retest reliability and validity of the Sedentary, Transportation and Activity Questionnaire (STAQ), a newly developed questionnaire dedicated to assessing context-specific SB, TRA and PA. Ninety six subjects (51 women) kept a contextualized activity-logbook and wore a hip accelerometer (Actigraph GT3X + (TM)) for a 7-day or 14-day period, at the end of which they completed the STAQ. Activity-energy expenditure was measured in a subgroup of 45 subjects using the double labeled water (DLW) method. Test-retest reliability was assessed using intra-class-coefficients (ICC) in a subgroup of 32 subjects who filled the questionnaire twice one month apart. Accelerometry was annotated using the logbook to obtain total and context-specific objective estimates of SB. Spearman correlations, Bland-Altman plots and ICC were used to analyze validity with logbook, accelerometry and DLW data validity criteria. Test-retest reliability was fair for total sitting time (ICC = 0.52), good to excellent for work sitting time (ICC = 0.71), transport-related walking (ICC = 0.61) and car use (ICC = 0.67), and leisure screen-related SB (ICC = 0.64-0.79), but poor for total sitting time during leisure and transport-related contexts. For validity, compared to accelerometry, significant correlations were found for STAQ estimates of total (r = 0.54) and context-specific sitting times with stronger correlations for work sitting time (r = 0.88), and screen times (TV/DVD viewing: r = 0.46; other screens: r = 0.42) than for transport (r = 0.35) or leisure-related sitting-times (r

  18. EFSA Panels on Biological Hazards (BIOHAZ), on Contaminants in the Food Chain (CONTAM), and on Animal Health and Welfare (AHAW); Scientific Opinion on the public health hazards to be covered by inspection of meat (poultry)

    DEFF Research Database (Denmark)

    Hald, Tine

    2012-01-01

    be risk categorisation of flocks based on FCI and classification of abattoirs according to their capability to reduce carcass faecal contamination. It is proposed that post-mortem visual inspection is replaced by setting targets for the main hazards on the carcass, and by verification of the food business......A qualitative risk assessment identified Campylobacter spp., Salmonella spp. and ESBL/AmpC gene-carrying bacteria as the most relevant biological hazards in the context of meat inspection of poultry. As none of these are detected by traditional visual meat inspection, establishing an integrated...... food safety assurance system, achievable through improved food chain information (FCI) and risk-based interventions, was proposed. This includes setting targets at carcass level and, when appropriate, flock level indicating what should be achieved for a given hazard. Elements of the system would...

  19. Quantum Chemistry on Quantum Computers: A Polynomial-Time Quantum Algorithm for Constructing the Wave Functions of Open-Shell Molecules.

    Science.gov (United States)

    Sugisaki, Kenji; Yamamoto, Satoru; Nakazawa, Shigeaki; Toyota, Kazuo; Sato, Kazunobu; Shiomi, Daisuke; Takui, Takeji

    2016-08-18

    Quantum computers are capable to efficiently perform full configuration interaction (FCI) calculations of atoms and molecules by using the quantum phase estimation (QPE) algorithm. Because the success probability of the QPE depends on the overlap between approximate and exact wave functions, efficient methods to prepare accurate initial guess wave functions enough to have sufficiently large overlap with the exact ones are highly desired. Here, we propose a quantum algorithm to construct the wave function consisting of one configuration state function, which is suitable for the initial guess wave function in QPE-based FCI calculations of open-shell molecules, based on the addition theorem of angular momentum. The proposed quantum algorithm enables us to prepare the wave function consisting of an exponential number of Slater determinants only by a polynomial number of quantum operations.

  20. New interpretation on formation of UO2 Post-Accident Heat Removal particulate in sodium

    International Nuclear Information System (INIS)

    Schins, H.

    1986-01-01

    A comparative experimental study on quenching in sodium of four molten fuel materials, UO 2 Al 2 P 3 , Cu and stainless steel, is presented. Experimental results like temperatures, pressures, particle shapes, particle size distributions, crack patterns and crystal grain sizes are given and interpreted. These fuel-coolant interactions (FCI) can be understood as all being characterized by transition boiling of sodium. The fuel is first fragmented by the sodium vapor bubble growth and collapse process. These particulates have smooth surfaces. The two materials, UO 2 and Al 2 O 3 , are fragmented further by a delayed mechanism which is thermal stress shrinkage cracking. Delayed particles are fragments of larger ones. Furthermore, attention is drawn to the theoretical results which show that pure FCI-particulate is significantly finer

  1. Relations among physical activity patterns, lifestyle activities, and fundamental movement skills for Finnish students in grade 7.

    Science.gov (United States)

    Jaakkola, Timo; Kalaja, Sami; Liukkonen, Jarmo; Jutila, Ari; Virtanen, Petri; Watt, Anthony

    2009-02-01

    To investigate the relations among leisure time physical activity and in sport clubs, lifestyle activities, and the locomotor, balance manipulative skills of Grade 7 students participating in Finnish physical education at a secondary school in central Finland completed self-report questionnaires on their physical activity patterns at leisure time and during sport club participation, and time spent watching television and using the computer and other electronic media. Locomotor skills were analyzed by the leaping test, balance skills by the flamingo standing test, and manipulative skills by the accuracy throwing test. Analysis indicated physical activity in sport clubs positively explained scores on balance and locomotor tests but not on accuracy of throwing. Leisure time physical activity and lifestyle activities were not statistically significant predictors of performance on any movement skill tests. Girls scored higher on the static balance skill and boys higher on the throwing task. Overall, physical activity in sport clubs was more strongly associated with performance on the fundamental movement tasks than was physical activity during leisure.

  2. Enzyme Enzyme activities in relation to sugar accumulation in tomato

    International Nuclear Information System (INIS)

    Alam, M.J.; Rahman, M.H.; Mamun, M.A.; Islam, K.

    2006-01-01

    Enzyme activities in tomato juice of five different varieties viz. Ratan, Marglove, BARI-1, BARI-5 and BARI-6, in relation to sugar accumulation were investigated at different maturity stages. The highest amount of invertase and beta-galactosidase was found in Marglove and the lowest in BARI- 6 at all maturity stages. Total soluble sugar and sucrose contents were highest in BARI-1 and lowest in BARI-6. The activity of amylase was maximum in Ratan and minimum in Marglove. Protease activity was highest in Ratan and lowest in BARI-6. BARI-1 contained the highest cellulase activity and the lowest in BARI-5. The amount of total soluble sugar and sucrose increased moderately from premature to ripe stage. The activities of amylase and cellulase increased up to the mature stage and then decreased drastically in the ripe stage. The activities of invertase and protease increased sharply from the premature to the ripe stage while the beta-galactosidase activity decreased remarkably. No detectable amount of reducing sugar was present in the premature stage in all cultivars of tomato but increased thereafter upto the ripe stage. The highest reducing sugar was present in BARI-5 in all of the maturity stages. (author)

  3. Error-related anterior cingulate cortex activity and the prediction of conscious error awareness

    Directory of Open Access Journals (Sweden)

    Catherine eOrr

    2012-06-01

    Full Text Available Research examining the neural mechanisms associated with error awareness has consistently identified dorsal anterior cingulate activity (ACC as necessary but not predictive of conscious error detection. Two recent studies (Steinhauser and Yeung, 2010; Wessel et al. 2011 have found a contrary pattern of greater dorsal ACC activity (in the form of the error-related negativity during detected errors, but suggested that the greater activity may instead reflect task influences (e.g., response conflict, error probability and or individual variability (e.g., statistical power. We re-analyzed fMRI BOLD data from 56 healthy participants who had previously been administered the Error Awareness Task, a motor Go/No-go response inhibition task in which subjects make errors of commission of which they are aware (Aware errors, or unaware (Unaware errors. Consistent with previous data, the activity in a number of cortical regions was predictive of error awareness, including bilateral inferior parietal and insula cortices, however in contrast to previous studies, including our own smaller sample studies using the same task, error-related dorsal ACC activity was significantly greater during aware errors when compared to unaware errors. While the significantly faster RT for aware errors (compared to unaware was consistent with the hypothesis of higher response conflict increasing ACC activity, we could find no relationship between dorsal ACC activity and the error RT difference. The data suggests that individual variability in error awareness is associated with error-related dorsal ACC activity, and therefore this region may be important to conscious error detection, but it remains unclear what task and individual factors influence error awareness.

  4. Age-related impairments in active learning and strategic visual exploration

    Directory of Open Access Journals (Sweden)

    Kelly L Brandstatt

    2014-02-01

    Full Text Available Old age could impair memory by disrupting learning strategies used by younger individuals. We tested this possibility by manipulating the ability to use visual-exploration strategies during learning. Subjects controlled visual exploration during active learning, thus permitting the use of strategies, whereas strategies were limited during passive learning via predetermined exploration patterns. Performance on tests of object recognition and object-location recall was matched for younger and older subjects for objects studied passively, when learning strategies were restricted. Active learning improved object recognition similarly for younger and older subjects. However, active learning improved object-location recall for younger subjects, but not older subjects. Exploration patterns were used to identify a learning strategy involving repeat viewing. Older subjects used this strategy less frequently and it provided less memory benefit compared to younger subjects. In previous experiments, we linked hippocampal-prefrontal co-activation to improvements in object-location recall from active learning and to the exploration strategy. Collectively, these findings suggest that age-related memory problems result partly from impaired strategies during learning, potentially due to reduced hippocampal-prefrontal co-engagement.

  5. Age-related impairments in active learning and strategic visual exploration.

    Science.gov (United States)

    Brandstatt, Kelly L; Voss, Joel L

    2014-01-01

    Old age could impair memory by disrupting learning strategies used by younger individuals. We tested this possibility by manipulating the ability to use visual-exploration strategies during learning. Subjects controlled visual exploration during active learning, thus permitting the use of strategies, whereas strategies were limited during passive learning via predetermined exploration patterns. Performance on tests of object recognition and object-location recall was matched for younger and older subjects for objects studied passively, when learning strategies were restricted. Active learning improved object recognition similarly for younger and older subjects. However, active learning improved object-location recall for younger subjects, but not older subjects. Exploration patterns were used to identify a learning strategy involving repeat viewing. Older subjects used this strategy less frequently and it provided less memory benefit compared to younger subjects. In previous experiments, we linked hippocampal-prefrontal co-activation to improvements in object-location recall from active learning and to the exploration strategy. Collectively, these findings suggest that age-related memory problems result partly from impaired strategies during learning, potentially due to reduced hippocampal-prefrontal co-engagement.

  6. Attentional control activation relates to working memory in attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Burgess, Gregory C; Depue, Brendan E; Ruzic, Luka; Willcutt, Erik G; Du, Yiping P; Banich, Marie T

    2010-04-01

    Attentional control difficulties in individuals with attention-deficit/hyperactivity disorder (ADHD) might reflect poor working memory (WM) ability, especially because WM ability and attentional control rely on similar brain regions. The current study examined whether WM ability might explain group differences in brain activation between adults with ADHD and normal control subjects during attentional demand. Participants were 20 adults with ADHD combined subtype with no comorbid psychiatric or learning disorders and 23 control subjects similar in age, IQ, and gender. The WM measures were obtained from the Wechsler Adult Intelligence Scale-III and Wechsler Memory Scale-Revised. Brain activation was assessed with functional magnetic resonance imaging (fMRI) while performing a Color-Word Stroop task. Group differences in WM ability explained a portion of the activation in left dorsolateral prefrontal cortex (DLPFC), which has been related to the creation and maintenance of an attentional set for task-relevant information. In addition, greater WM ability predicted increased activation of brain regions related to stimulus-driven attention and response selection processes in the ADHD group but not in the control group. The inability to maintain an appropriate task set in young adults with combined type ADHD, associated with decreased activity in left DLPFC, might in part be due to poor WM ability. Furthermore, in individuals with ADHD, higher WM ability might relate to increased recruitment of stimulus-driven attention and response selection processes, perhaps as a compensatory strategy. Copyright 2010 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  7. Physical Activity and Smoking Habits in Relation to Weight Status ...

    African Journals Online (AJOL)

    Purpose: Understanding factors that impact overweight or obesity is an essential step towards formulating programs to prevent or control obesity in young adults. Thus, we aim to assess the prevalence of physical activity and smoking habits in relation to weight status among a sample of university students. Methods: A ...

  8. CFD Activity at Aerojet Related to Seals and Fluid Film Bearing

    Science.gov (United States)

    Bache, George E.

    1991-01-01

    Computational Fluid Dynamics (CFD) activities related to seals and fluid film bearings are presented. Among the topics addressed are the following: Aerovisc Numeric and its capabilities; Recent Seal Applications; and Future Code Developments.

  9. Maternal involvement in children's leisure activities in rural China: Relations with adjustment outcomes.

    Science.gov (United States)

    Zhao, Siman; Chen, Xinyin

    2018-02-01

    This 1-year longitudinal study examined maternal involvement in children's leisure activities and its relations with children's adjustment in rural China. Participants included 184 children (93 boys and 91 girls) initially in third grade (mean age = 9.31 years). Children were asked to report the frequencies of mothers' involvement in leisure activities. Information on children's social, school, and psychological adjustment were collected from multiple sources including peer evaluations, teacher ratings, self-reports, and school records. The results showed that children's perceptions of maternal involvement in leisure activities positively predicted later social and school adjustment, particularly in boys. Furthermore, child initial adjustment status moderated the relations between maternal leisure activity involvement and child outcomes. The results suggest that maternal involvement in children's leisure activities, which has traditionally been neglected in the society, is a significant factor in contributing to child development in today's rural China. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  10. The Use of Social Networking Sites in Job Related Activities: A Cross-cultural Comparison

    Directory of Open Access Journals (Sweden)

    Małgorzata Bartosik-Purgat

    2017-06-01

    Full Text Available Objective: The main objective of the paper is to identify the use of Social Networking Sites (SNSs in job related activities and indicate the interdependencies between these activities and age, gender, as well as education in culturally diversified markets (China, Poland, Turkey, the United States. Research Design & Methods: In the exploratory empirical study the authors used two research methods: PAPI (Paper and Pen Personal Interview and CAWI (Computer Assisted Web Interview. The empirical data were collected in 2016 and the total number of respondents from four culturally diversified countries was 1246. Findings: The analysis with the use of Kruskal-Wallis and Dunn post-hoc tests showed that the Turkish respondents most often use SNSs for job related activities, while it is the least often done by the studied Americans. Moreover, from among the studied factors (gender, age and education level that differentiate the SNSs usage for job related activities in a statistically significant way age is of greatest importance. Implications & Recommendations: The results of the research provide implications for the recruitment policy of multinational enterprises (MNEs. Since more and more enterprises use SNSs in order to look for new employees and advertise themselves as employers (employer branding, the identified interdependencies between the SNSs activities and the analysed factors can support firm attempts to develop the proper recruitment policy taking into account the cultural diversity of potential workers. Contribution & Value Added: There are not many studies in the literature which present the usage of SNSs for job related activities from the perspective of individual users in the cross-cultural approach. The majority of studies are related to the usage of SNSs by enterprises in the recruitment process.

  11. Health-related quality of life, physical activity, and sedentary behavior of adults with visual impairments.

    Science.gov (United States)

    Haegele, Justin A; Famelia, Ruri; Lee, Jihyun

    2017-11-01

    Research suggests that physical activity and sedentary behaviors can impact one's health-related quality of life (HRQoL). However, little is known about the impact that these behaviors can have on the HRQoL of those with visual impairments. Therefore, the primary purpose of this study was to determine the associations of physical activity and sedentary behavior with HRQoL among a sample of adults with visual impairments. Individuals with visual impairments were invited via email to complete three questionnaires: (a) the international physical activity questionnaire-short form, (b) the Rasch-revised versions of the World Health Organization Quality of Life instrument with the Level of Independence subscale, and (c) a demographic questionnaire. Eighty participants (M age   =   47.5) provided usable surveys for analyses. The results demonstrated that physical activity significantly predicted HRQoL (F(2,79) = 3.508, p = .035, R 2 Adjusted =.060), yet, sedentary behavior did not (F(2,79) = 1.546, p = .220, R 2  = .039, R 2 Adjusted =.014). Gender differences were uncovered regarding the relationship between physical activity and health-related quality of life. The findings of this study demonstrate the importance of physical activity in influencing the HRQoL of adults with visual impairments. This study supports the need for additional intervention research to promote physical activity for those with visual impairments. Implications for Rehabilitations Adults with visual impairments tend to report lower health-related quality of life than peers without visual impairments. Regular participation in leisure-time physical activity, and restricted sedentary time, have been demonstrated to positively influence health-related quality of life for adults without disabilities. In this study, physical activity shows promise as an effective means of improving health-related quality of life for adults with visual impairments.

  12. Combating Corruption Relates Money Laundering Activities in Indonesia: A Hope and Reality

    OpenAIRE

    Handoyo, Sigit

    2009-01-01

    Corruption in Indonesia has become a culture and systemic so that it could not be eradicated in the short period of time. As corruption is closely related to money laundering activities, it is not impossible that combating corruption also means combating money laun-dering activities. PPATK (Pusat Pengkajian dan Analisis Transaksi Keuangan) as the Indone-sia’s FIU (Financial Intelligence Unit) has hard works to reveal those money laundering and corruptions activities. Beside its obstacles, PPA...

  13. A Study of Cyber Security Activities for Development of Safety-related Controller

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Myeongkyun; Song, Seunghwan; Yoo, Kwanwoo; Yun, Donghwa [Korea Univ., Seoul (Korea, Republic of)

    2014-05-15

    Nuclear Power Plant Regulatory guide describes the regulatory requirements to implement cyber security activities to ensure that design and operate to respond to cyber threats that exploited to vulnerability of digital-based technologies associated with safety-related digital instrumentation and control systems at nuclear power plants. Cyber security activities coverage is instrumentation and control systems to perform safety functions and digital-based equipment to use development, test, analysis and asset for instrumentation and control systems. Regulatory guidance is required to the cyber security activities that should be performed in each development phase of safety-related controller. Development organization should establish and implement to cyber security plans for responding to cyber threats throughout each lifecycle phase and the result of the cyber security activities should be generated to the documents. In addition, the independent verification and validation organization should perform simulated penetration test for enhancing response capabilities to cyber security threats and development organization should establish and implement response hardening solutions for the cyber security vulnerabilities identified in the simulated penetration test.

  14. A Study of Cyber Security Activities for Development of Safety-related Controller

    International Nuclear Information System (INIS)

    Lee, Myeongkyun; Song, Seunghwan; Yoo, Kwanwoo; Yun, Donghwa

    2014-01-01

    Nuclear Power Plant Regulatory guide describes the regulatory requirements to implement cyber security activities to ensure that design and operate to respond to cyber threats that exploited to vulnerability of digital-based technologies associated with safety-related digital instrumentation and control systems at nuclear power plants. Cyber security activities coverage is instrumentation and control systems to perform safety functions and digital-based equipment to use development, test, analysis and asset for instrumentation and control systems. Regulatory guidance is required to the cyber security activities that should be performed in each development phase of safety-related controller. Development organization should establish and implement to cyber security plans for responding to cyber threats throughout each lifecycle phase and the result of the cyber security activities should be generated to the documents. In addition, the independent verification and validation organization should perform simulated penetration test for enhancing response capabilities to cyber security threats and development organization should establish and implement response hardening solutions for the cyber security vulnerabilities identified in the simulated penetration test

  15. Physical activity in relation to urban environments in 14 cities worldwide

    DEFF Research Database (Denmark)

    Sallis, James F; Cerin, Ester; Conway, Terry L

    2016-01-01

    BACKGROUND: Physical inactivity is a global pandemic responsible for over 5 million deaths annually through its effects on multiple non-communicable diseases. We aimed to document how objectively measured attributes of the urban environment are related to objectively measured physical activity......, in an international sample of adults. METHODS: We based our analyses on the International Physical activity and Environment Network (IPEN) adult study, which was a coordinated, international, cross-sectional study. Participants were sampled from neighbourhoods with varied levels of walkability and socioeconomic......'s residential address with geographic information systems. Mean daily minutes of moderate-to-vigorous-intensity physical activity were measured with 4-7 days of accelerometer monitoring. Associations between environmental attributes and physical activity were estimated using generalised additive mixed models...

  16. Legalization of prostitution and decriminalization of related activities in Ukraine

    OpenAIRE

    Олександр Едуардович Радутний

    2016-01-01

    The paper discusses pros and cons of the legalization of prostitution and decriminalization of related activities, proves the necessity of resolving the issue from the perspective of human rights and interests of society, proposes changes to the current legislation of Ukraine and specific methods of information support of this process.

  17. ICT and quality of teaching–learning related activities in primary ...

    African Journals Online (AJOL)

    The paper is a report of a study carried out to examine how information and communication technology (ICT) enhance teaching learning related activities in primary schools in Ogoja education zone of Cross River State, Nigeria. To achieve the purpose of the study, one research question was formulated to direct the study.

  18. Activity, inactivity, and screen time in relation to weight and fatness over adolescence in girls.

    Science.gov (United States)

    Must, Aviva; Bandini, Linda G; Tybor, David J; Phillips, Sarah M; Naumova, Elena N; Dietz, William H

    2007-07-01

    The impact of activity and inactivity on relative weight and fatness change are best evaluated longitudinally. We examined the longitudinal relationship of physical activity, inactivity, and screen time with relative weight status and percentage body fat (%BF) and explored how it differed by parental overweight status. Non-obese pre-menarcheal girls (173), 8 to 12 years old, were followed until 4 years post-menarche. %BF, BMI z-score, and time spent sleeping, sitting, standing, walking, and in vigorous activity were assessed annually. We developed a physical activity index to reflect time and intensity of activity. Inactivity was defined as the sum of time spent sleeping, sitting, and standing. Screen time was defined as time spent viewing television, videotapes, or playing video games. Parental overweight was defined as at least one parent with BMI>25. In separate linear mixed effects models, activity, inactivity, and screen time were unrelated to BMI z-score longitudinally, with and without accounting for parental overweight. After controlling for parental overweight, activity was inversely related (phistory of overweight represent a target population of high priority for interventions around physical activity and inactivity.

  19. Age-Related Increase in Electromyography Burst Activity in Males and Females

    Directory of Open Access Journals (Sweden)

    Olga Theou

    2013-01-01

    Full Text Available The rapid advancement of electromyography (EMG technology facilitates measurement of muscle activity outside the laboratory during daily life. The purpose of this study was to determine whether bursts in EMG recorded over a typical 8-hour day differed between young and old males and females. Muscle activity was recorded from biceps brachii, triceps brachii, vastus lateralis, and biceps femoris of 16 young and 15 old adults using portable surface EMG. Old muscles were active 16–27% of the time compared to 5–9% in young muscles. The number of bursts was greater in old than young adults and in females compared to males. Burst percentage and mean amplitude were greater in the flexor muscles compared with the extensor muscles. The greater burst activity in old adults coupled with the unique activity patterns across muscles in males and females provides further understanding of how changes in neuromuscular activity effects age-related functional decline between the sexes.

  20. Frontal eye field sends delay activity related to movement, memory, and vision to the superior colliculus.

    Science.gov (United States)

    Sommer, M A; Wurtz, R H

    2001-04-01

    Many neurons within prefrontal cortex exhibit a tonic discharge between visual stimulation and motor response. This delay activity may contribute to movement, memory, and vision. We studied delay activity sent from the frontal eye field (FEF) in prefrontal cortex to the superior colliculus (SC). We evaluated whether this efferent delay activity was related to movement, memory, or vision, to establish its possible functions. Using antidromic stimulation, we identified 66 FEF neurons projecting to the SC and we recorded from them while monkeys performed a Go/Nogo task. Early in every trial, a monkey was instructed as to whether it would have to make a saccade (Go) or not (Nogo) to a target location, which permitted identification of delay activity related to movement. In half of the trials (memory trials), the target disappeared, which permitted identification of delay activity related to memory. In the remaining trials (visual trials), the target remained visible, which permitted identification of delay activity related to vision. We found that 77% (51/66) of the FEF output neurons had delay activity. In 53% (27/51) of these neurons, delay activity was modulated by Go/Nogo instructions. The modulation preceded saccades made into only part of the visual field, indicating that the modulation was movement-related. In some neurons, delay activity was modulated by Go/Nogo instructions in both memory and visual trials and seemed to represent where to move in general. In other neurons, delay activity was modulated by Go/Nogo instructions only in memory trials, which suggested that it was a correlate of working memory, or only in visual trials, which suggested that it was a correlate of visual attention. In 47% (24/51) of FEF output neurons, delay activity was unaffected by Go/Nogo instructions, which indicated that the activity was related to the visual stimulus. In some of these neurons, delay activity occurred in both memory and visual trials and seemed to represent a

  1. Social Activity, School-Related Activity, and Anti-Substance Use Media Messages on Adolescent Tobacco and Alcohol Use

    OpenAIRE

    Moon, Sung Seek; Rao, Uma

    2011-01-01

    In this article, we present the effects of three hypothesized protective factors: social activities, school-related activities, and anti-substance use media messages on adolescent tobacco and alcohol use. Data were drawn from the “Monitoring the Future” (MTF) research project, which was conducted by the Institute for Social Research at the University of Michigan. The sample included 2,551 twelfth-grade students. The results of the structural equation model showed that exposure to media anti-d...

  2. Legalization of prostitution and decriminalization of related activities in Ukraine

    Directory of Open Access Journals (Sweden)

    Олександр Едуардович Радутний

    2016-06-01

    Full Text Available The paper discusses pros and cons of the legalization of prostitution and decriminalization of related activities, proves the necessity of resolving the issue from the perspective of human rights and interests of society, proposes changes to the current legislation of Ukraine and specific methods of information support of this process.

  3. Self-Reported Physical Activity within and outside the Neighborhood: Criterion-Related Validity of the Neighborhood Physical Activity Questionnaire in German Older Adults

    Science.gov (United States)

    Bödeker, Malte; Bucksch, Jens; Wallmann-Sperlich, Birgit

    2018-01-01

    The Neighborhood Physical Activity Questionnaire allows to assess physical activity within and outside the neighborhood. Study objectives were to examine the criterion-related validity and health/functioning associations of Neighborhood Physical Activity Questionnaire-derived physical activity in German older adults. A total of 107 adults aged…

  4. Functional activity of the sensorimotor cortex and cerebellum relates to cervical dystonia symptoms.

    Science.gov (United States)

    Burciu, Roxana G; Hess, Christopher W; Coombes, Stephen A; Ofori, Edward; Shukla, Priyank; Chung, Jae Woo; McFarland, Nikolaus R; Wagle Shukla, Aparna; Okun, Michael S; Vaillancourt, David E

    2017-09-01

    Cervical dystonia (CD) is the most common type of focal dystonia, causing abnormal movements of the neck and head. In this study, we used noninvasive imaging to investigate the motor system of patients with CD and uncover the neural correlates of dystonic symptoms. Furthermore, we examined whether a commonly prescribed anticholinergic medication in CD has an effect on the dystonia-related brain abnormalities. Participants included 16 patients with CD and 16 healthy age-matched controls. We collected functional MRI scans during a force task previously shown to extensively engage the motor system, and diffusion and T1-weighted MRI scans from which we calculated free-water and brain tissue densities. The dystonia group was also scanned ca. 2 h after a 2-mg dose of trihexyphenidyl. Severity of dystonia was assessed pre- and post-drug using the Burke-Fahn-Marsden Dystonia Rating Scale. Motor-related activity in CD was altered relative to controls in the primary somatosensory cortex, cerebellum, dorsal premotor and posterior parietal cortices, and occipital cortex. Most importantly, a regression model showed that increased severity of symptoms was associated with decreased functional activity of the somatosensory cortex and increased activity of the cerebellum. Structural imaging measures did not differ between CD and controls. The single dose of trihexyphenidyl altered the fMRI signal in the somatosensory cortex but not in the cerebellum. Symptom severity was not significantly reduced post-treatment. Findings show widespread changes in functional brain activity in CD and most importantly that dystonic symptoms relate to disrupted activity in the somatosensory cortex and cerebellum. Hum Brain Mapp 38:4563-4573, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  5. Leisure time physical activity and health-related quality of life.

    Science.gov (United States)

    Vuillemin, Anne; Boini, Stéphanie; Bertrais, Sandrine; Tessier, Sabrina; Oppert, Jean-Michel; Hercberg, Serge; Guillemin, Francis; Briançon, Serge

    2005-08-01

    There are few data on the relationship between health-related quality of life (HRQoL) and leisure time physical activity (LTPA) in the general population. We investigated the relationships of meeting public health recommendations (PHR) for moderate and vigorous physical activity with HRQoL in French adult subjects. LTPA and HRQoL were assessed in 1998 in 2333 men and 3321 women from the SU.VI.MAX. cohort using the French versions of the Modifiable Activity Questionnaire (MAQ) and the SF-36 questionnaire, respectively. Relationship between LTPA and HRQoL was assessed using analysis of variance. Results from multivariate analysis showed that meeting physical activity recommended levels was associated with higher HRQoL scores (except in Bodily pain dimension for women): differences in mean HRQoL scores between subjects meeting or not PHR ranged from 2.4 (Mental health) to 4.5 (Vitality) and from 2.2 (Bodily pain) to 5.7 (Vitality) for women and men, respectively. Subjects meeting PHR for physical activity had better HRQoL than those who did not. Our data suggest that 30' of moderate LTPA per day on a regular basis may be beneficial on HRQoL. Higher intensity LTPA is associated with greater HRQoL. This emphasizes the importance to promote at least moderate physical activity.

  6. Estrus Traits Derived from Activity Measurements are Heritable and Closely Related to Conventional

    DEFF Research Database (Denmark)

    Ismael, Ahmed Ismael Sayed; Kargo, Morten; Fogh, Anders

    This study was aimed at assessing the genetic parameters for fertility-related traits, comparing the interval from calving to first insemination (ICF) to physical activity traits, especially days from calving to first high activity, DFHA. Data from commercial Holstein herds included insemination ...

  7. Physical activity patterns in patients with early and late age-related macular degeneration

    DEFF Research Database (Denmark)

    Subhi, Yousif; Sørensen, Torben Lykke

    2016-01-01

    INTRODUCTION: Age-related macular degeneration (AMD) leads to visual impairment that affects visual functioning and thereby the ability to be physically active. We investigated physical activity patterns in patients with AMD. METHODS: Patients with early and late AMD and elderly controls were...

  8. Reactive oxygen species-related activities of nano-iron metal and nano-iron oxides.

    Science.gov (United States)

    Wu, Haohao; Yin, Jun-Jie; Wamer, Wayne G; Zeng, Mingyong; Lo, Y Martin

    2014-03-01

    Nano-iron metal and nano-iron oxides are among the most widely used engineered and naturally occurring nanostructures, and the increasing incidence of biological exposure to these nanostructures has raised concerns about their biotoxicity. Reactive oxygen species (ROS)-induced oxidative stress is one of the most accepted toxic mechanisms and, in the past decades, considerable efforts have been made to investigate the ROS-related activities of iron nanostructures. In this review, we summarize activities of nano-iron metal and nano-iron oxides in ROS-related redox processes, addressing in detail the known homogeneous and heterogeneous redox mechanisms involved in these processes, intrinsic ROS-related properties of iron nanostructures (chemical composition, particle size, and crystalline phase), and ROS-related bio-microenvironmental factors, including physiological pH and buffers, biogenic reducing agents, and other organic substances. Copyright © 2014. Published by Elsevier B.V.

  9. Status of research reactor utilization and other related activities

    International Nuclear Information System (INIS)

    Calix, V.S.

    2004-01-01

    The report covers two parts; the first is on the progress of the cooperative projects planned for 2002 under the FNCA and the other part on the activities related to the PRR1, Philippine Research Reactor. In the 2001 Workshop at Beijing, the Country agreed to participate in the three areas for collaboration. A brief reports on these three projects are included. The Country representatives during this 2002 Workshop will do a more detailed presentation on Radioisotope Production (TcG) and Neutron Activation Analysis projects. The second part of this report deals with the issues/concerns impeding the rehabilitation of PRR1. In January 2002, the Institute created the PRR1 Strategic Plan Committee to look deeply into these issues and concerns. The results of the Committee's work are discussed. (author)

  10. OECD/NEA Ongoing activities related to the nuclear fuel cycle

    International Nuclear Information System (INIS)

    Cornet, S.M.; McCarthy, K.; Chauvin, N.

    2013-01-01

    As part of its role in encouraging international collaboration, the OECD Nuclear Energy Agency is coordinating a series of projects related to the Nuclear Fuel Cycle. The Nuclear Science Committee (NSC) Working Party on Scientific Issues of the Nuclear Fuel Cycle (WPFC) comprises five different expert groups covering all aspects of the fuel cycle from front to back-end. Activities related to fuels, materials, physics, separation chemistry, and fuel cycles scenarios are being undertaken. By publishing state-of-the-art reports and organizing workshops, the groups are able to disseminate recent research advancements to the international community. Current activities mainly focus on advanced nuclear systems, and experts are working on analyzing results and establishing challenges associated to the adoption of new materials and fuels. By comparing different codes, the Expert Group on Advanced Fuel Cycle Scenarios is aiming at gaining further understanding of the scientific issues and specific national needs associated with the implementation of advanced fuel cycles. At the back end of the fuel cycle, separation technologies (aqueous and pyrochemical processing) are being assessed. Current and future activities comprise studies on minor actinides separation and post Fukushima studies. Regular workshops are also organized to discuss recent developments on Partitioning and Transmutation. In addition, the Nuclear Development Committee (NDC) focuses on the analysis of the economics of nuclear power across the fuel cycle in the context of changes of electricity markets, social acceptance and technological advances and assesses the availability of the nuclear fuel and infrastructure required for the deployment of existing and future nuclear power. The Expert Group on the Economics of the Back End of the Nuclear Fuel Cycle (EBENFC), in particular, is looking at assessing economic and financial issues related to the long term management of spent nuclear fuel. (authors)

  11. Directed Activities Related to Text: Text Analysis and Text Reconstruction.

    Science.gov (United States)

    Davies, Florence; Greene, Terry

    This paper describes Directed Activities Related to Text (DART), procedures that were developed and are used in the Reading for Learning Project at the University of Nottingham (England) to enhance learning from texts and that fall into two broad categories: (1) text analysis procedures, which require students to engage in some form of analysis of…

  12. Activity in ventromedial prefrontal cortex during self-related processing: positive subjective value or personal significance?

    Science.gov (United States)

    Kim, Kyungmi; Johnson, Marcia K

    2015-04-01

    Well-being and subjective experience of a coherent world depend on our sense of 'self' and relations between the self and the environment (e.g. people, objects and ideas). The ventromedial prefrontal cortex (vMPFC) is involved in self-related processing, and disrupted vMPFC activity is associated with disruptions of emotional/social functioning (e.g. depression and autism). Clarifying precise function(s) of vMPFC in self-related processing is an area of active investigation. In this study, we sought to more specifically characterize the function of vMPFC in self-related processing, focusing on two alternative accounts: (i) assignment of positive subjective value to self-related information and (ii) assignment of personal significance to self-related information. During functional magnetic resonance imaging (fMRI), participants imagined owning objects associated with either their perceived ingroup or outgroup. We found that for ingroup-associated objects, vMPFC showed greater activity for objects with increased than decreased post-ownership preference. In contrast, for outgroup-associated objects, vMPFC showed greater activity for objects with decreased than increased post-ownership preference. Our findings support the idea that the function of vMPFC in self-related processing may not be to represent/evaluate the 'positivity' or absolute preference of self-related information but to assign personal significance to it based on its meaning/function for the self. © The Author (2014). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  13. HL-2A experiment and ITER-related activity at SWIP

    International Nuclear Information System (INIS)

    Duan Xuru

    2007-01-01

    In this overview the recent progress on HL-2A tokamak experiment and ITER-related activity at SWIP is summarized. Experiment on HL-2A is one of the important research activities at SWIP. In the last two years, some new hardware had been developed, these include four sets of ECRH system with a total power up to 2 MW, new diagnostics such as 8-channel laser interferometer. The studied subjects were focused on plasma auxiliary heating, fuelling, transport, edge plasma physics and turbulence, etc. Progress in these fields has been obtained. For example, the toroidal symmetry of the geodesic acoustic mode (GAM), the oscillating branch of zonal flows has been demonstrated for the first time using a novel 3-step Langmuir Probe, and the poloidal and radial structure of the low frequency electric potential and field were simultaneously observed. During ECRH experiments under different discharge conditions, the MHD instability excited by high energetic electrons was investigated. Besides, non-local heat transport due to SMBI during ECRH was studied. Another important fusion activity at SWIP is the ITER relevant technology. The R and D of four ITER procurements (first wall and shielding blanket, magnet gravity support, gas injection and glow discharge cleaning system, neutron flux measurement) has been undertaken. Progress has been made, e.g. the technology for manufacturing high purity (>99%) ITER specified Be plate and CuCrZr alloy is obtained, their major mechanical and physical properties were measured. For ITER-TBM, a structural material named as CLF-1, a type of reduced activation ferritic/martenstic steel, was developed. Besides, some progress in fusion reactor design and related technology was achieved. (authors)

  14. A specific metabolic pattern related to the hallucinatory activity in schizophrenia

    International Nuclear Information System (INIS)

    Huret, J.D.; Martinot, J.L.; Lesur, A.; Mazoyer, B.; Pappata, S.; Syrota, A.; Baron, J.C.; Lemperiere, T.

    1988-01-01

    A clinical and PEI study using 18 F - fluorodesoxyglucose for measuring local cerebral glucose metabolism with the aim of showing a specific pattern related to the hallucinatory activity, is presented in schizophrenic patients all experiencing hallucinations or pseudo-halluccinations

  15. Natural radionuclides in soils - relation between soil properties and the activities

    International Nuclear Information System (INIS)

    Fujiyoshi, Ryoko; Nakayama, Masashi; Sawamura, Sadashi

    2000-01-01

    Vertical profiles of natural radionuclides (K-40 and Ra-226) have been investigated in a soil core with 8 m in depth to elucidate its relation to the bed rock activity and to several soil properties. Pattern of the Ra-226 activity with soil depth suggests inhomogeneity of this nuclide during the accumulating process. Radiometric sorption experiments with Pb-210 as a tracer gave the result that almost all Pb(II) in the soil solution disappeared to be sorbed to the soil components

  16. Gender differences in physical activity, sedentary behavior, and their relation to body composition in active Brazilian adolescents.

    Science.gov (United States)

    Nogueira, Julia Aparecida Devide; Macedo da Costa, Teresa Helena

    2009-01-01

    Body weight and composition are determined by genotype, environment, and energy balance. Physical activity or sedentary behavior have different associations with body weight, fat mass, and fat-free mass, a relationship that is not clear in adolescents. The aim of this study was to test the associations between gender, physical activity, sedentary behavior, and body composition in physically active adolescents. Weight, height, and skinfold thickness were measured in 326 physically active boys and girls age 11 to 15 years. All subjects answered a questionnaire assessing their usual daily activities for the last month. Time spent on each activity was used to estimate the physical activity level (PAL). PAL was associated with body composition after adjustment for age and maturation, with differences between genders. For boys, PAL was positively and significantly associated with body mass index (BMI) and fat-free mass index (beta=0.14 and 0.15, respectively). For girls, PAL was negatively and significantly associated with BMI and fat mass index (beta=-0.11 and -0.75, respectively). Sedentary behavior, expressed by hours of TV, videogame, and computer use, was not associated with any body-composition outcome for either gender. The accumulated amount of physical activity, but not of sedentary behavior, was related to body composition in active adolescents.

  17. 17 CFR 240.3a43-1 - Customer-related government securities activities incidental to the futures-related business of a...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Customer-related government securities activities incidental to the futures-related business of a futures commission merchant registered with the Commodity Futures Trading Commission. 240.3a43-1 Section 240.3a43-1 Commodity and Securities...

  18. Testosterone is inversely related to brain activity during emotional inhibition in schizophrenia.

    Directory of Open Access Journals (Sweden)

    Ans Vercammen

    Full Text Available Sex steroids affect cognitive function as well as emotion processing and regulation. They may also play a role in the pathophysiology of schizophrenia. However, the effects of sex steroids on cognition and emotion-related brain activation in schizophrenia are poorly understood. Our aim was to determine the extent to which circulating testosterone relates to brain activation in men with schizophrenia compared to healthy men during cognitive-emotional processing. We assessed brain activation in 18 men with schizophrenia and 22 age-matched healthy men during an emotional go/no-go task using fMRI and measured total serum testosterone levels on the same morning. We performed an ROI analysis to assess the relationship between serum testosterone and brain activation, focusing on cortical regions involved the emotional go/no-go task. Slower RT and reduced accuracy was observed when participants responded to neutral stimuli, while inhibiting responses to negative stimuli. Healthy men showed a robust increase in activation of the middle frontal gyrus when inhibiting responses to negative stimuli, but there was no significant association between activation and serum testosterone level in healthy men. Men with schizophrenia showed a less pronounced increase in activation when inhibiting responses to negative stimuli; however, they did show a strong inverse association between serum testosterone level and activation of the bilateral middle frontal gyrus and left insula. Additionally, increased accuracy during inhibition of response to negative words was associated with both higher serum testosterone levels and decreased activation of the middle frontal gyrus in men with schizophrenia only. We conclude that endogenous hormone levels, even within the normal range, may play an enhanced modulatory role in determining the neural and behavioural response during cognitive-emotional processing in schizophrenia.

  19. Cancer-related fatigue and physical activity among premenopausal cervical and endometrial cancer survivors in Japan

    OpenAIRE

    小濵, 京子; 丸, 光惠; 前田, 留美; 久保田, 俊郎

    2015-01-01

    Purpose: To examine the relationship between cancer-related fatigue (CRF) and physical activity in daily living in premenopausal disease-free cervical and endometrial cancer survivors. Methods: A physical activity monitor was used to collect objective data on daily physical activity. CRF and related variables were measured using self-report scales in a cross-sectional manner. Results: The average age was 44.9 years among 64 women. The higher CRF group comprised 22 women (34%), 10% of whom had...

  20. Physical activity is not related to semen quality in young healthy men

    Science.gov (United States)

    Mínguez-Alarcón, Lidia; Chavarro, Jorge E; Mendiola, Jaime; Gaskins, Audrey J; Torres-Cantero, Alberto M

    2015-01-01

    Objective To study the relation of physical activity with semen quality among healthy young men from Spain. Design Cross-sectional study. Setting University and college campuses of Murcia Region, Spain. Patients Healthy young men with untested fertility (n=215). Intervention A physical examination, blood and semen samples, and completion of a questionnaire. Main outcomes measure Semen quality parameters. Results Physical activity was not related to semen quality parameters. The adjusted percentage differences (95% confidence interval) in semen parameters comparing men in the top quartile of moderate to vigorous physical activity (≥9.5h/wk) to men in the bottom quartile (≤3h/wk) were 4.3% (−30.2, 38.9) for total sperm count, 7.2% (−30.6, 45.1) for sperm concentration, −2.42% (−6.53, 1.69) for sperm motility, and 12.6% (−12.0, 37.2) for sperm morphology. Conclusion In contrast to previous research among athletes, these data suggest that physical activity is not deleterious to testicular function, as captured by semen quality parameters in this population of healthy young men in Spain. PMID:25064411

  1. Relation of Perceived Health Competence to Physical Activity in Patients With Coronary Heart Disease.

    Science.gov (United States)

    Bachmann, Justin M; Mayberry, Lindsay S; Wallston, Kenneth A; Huang, Shi; Roumie, Christianne L; Muñoz, Daniel; Patel, Niral J; Kripalani, Sunil

    2018-05-01

    Physical inactivity is highly associated with mortality, especially in patients with coronary heart disease. We evaluated the effect of perceived health competence, a patient's belief in his or her ability to achieve health-related goals, on cumulative physical activity levels in the Mid-South Coronary Heart Disease Cohort Study. The Mid-South Coronary Heart Disease Cohort Study consists of 2,587 outpatients (32% were female) with coronary heart disease at an academic medical center network in the United States. Cumulative physical activity was quantified in metabolic equivalent (MET)-minutes per week with the International Physical Activity Questionnaire. We investigated associations between the 2-item Perceived Health Competence Scale (PHCS-2) and MET-minutes/week after adjusting for co-morbidities and psychosocial factors with linear regression. Nearly half of participants (47%) exhibited low physical activity levels (Perceived health competence was highly associated with physical activity after multivariable adjustment. A nonlinear relation was observed, with the strongest effect on physical activity occurring at lower levels of perceived health competence. There was effect modification by gender (p = 0.03 for interaction). The relation between perceived health competence and physical activity was stronger in women compared with men; an increase in the PHCS-2 from 3 to 4 was associated with a 73% increase in MET-minutes/week in women (95% confidence interval 43% to 109%, p perceived health competence was strongly associated with less physical activity in patients with coronary heart disease and may represent a potential target for behavioral interventions. Published by Elsevier Inc.

  2. African American Youths with Internalizing Difficulties: Relation to Social Support and Activity Involvement

    Science.gov (United States)

    Margolin, Sylvia

    2006-01-01

    Social support and positive activity involvement are considered protective factors that can help offset the risks for youths living in impoverished areas. This study investigated whether insufficient social support and activity involvement are related to internalizing difficulties, such as depression, anxiety, loneliness, and low self-esteem.…

  3. High arterial compliance in cirrhosis is related to low adrenaline and elevated circulating calcitonin gene related peptide but not to activated vasoconstrictor systems

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik Sahl; Møller, S; Schifter, S

    2001-01-01

    catecholamines, renin activity, endothelin-1, and calcitonin gene related peptide (CGRP) at baseline and during oxygen inhalation. RESULTS: COMP(art) was significantly increased in cirrhotic patients compared with controls (1.32 v 1.06 ml/mm Hg; padrenaline levels (r=-0.......001) and central circulation time (r=-0.49; padrenaline (-16%; p... to COMP(art) disappeared. The relation of COMP(art) to CGRP and circulatory variables remained unchanged. CONCLUSION: Elevated arterial compliance in cirrhosis is related to low adrenaline, high CGRP, and systemic hyperdynamics but not to indicators of the activated vasoconstrictor systems (noradrenaline...

  4. School Social Worker's Perceptions of the Frequency of Actual and Preferred Engagement in Role Related Activities

    Science.gov (United States)

    Arthur, Elizabeth

    2009-01-01

    The purpose of this study was (1) to determine the frequency in which school social workers in Virginia engage in and prefer to engage in social work related activities and (2) to determine if the frequency in which the social work related activities the school social workers engage in is related to select variables. After a comprehensive review…

  5. Assessing students' conceptual knowledge of electricity and magnetism

    Science.gov (United States)

    McColgan, Michele W.; Finn, Rose A.; Broder, Darren L.; Hassel, George E.

    2017-12-01

    We present the Electricity and Magnetism Conceptual Assessment (EMCA), a new assessment aligned with second-semester introductory physics courses. Topics covered include electrostatics, electric fields, circuits, magnetism, and induction. We have two motives for writing a new assessment. First, we find other assessments such as the Brief Electricity and Magnetism Assessment and the Conceptual Survey on Electricity and Magnetism not well aligned with the topics and content depth of our courses. We want to test introductory physics content at a level appropriate for our students. Second, we want the assessment to yield scores and gains comparable to the widely used Force Concept Inventory (FCI). After five testing and revision cycles, the assessment was finalized in early 2015 and is available online. We present performance results for a cohort of 225 students at Siena College who were enrolled in our algebra- and calculus-based physics courses during the spring 2015 and 2016 semesters. We provide pretest, post-test, and gain analyses, as well as individual question and whole test statistics to quantify difficulty and reliability. In addition, we compare EMCA and FCI scores and gains, and we find that students' FCI scores are strongly correlated with their performance on the EMCA. Finally, the assessment was piloted in an algebra-based physics course at George Washington University (GWU). We present performance results for a cohort of 130 GWU students and we find that their EMCA scores are comparable to the scores of students in our calculus-based physics course.

  6. Implications of Functional Capacity Loss and Fatality for Vehicle Safety Prioritization.

    Science.gov (United States)

    McMurry, Timothy L; Sherwood, Chris; Poplin, Gerald S; Seguí-Gómez, María; Crandall, Jeff

    2015-01-01

    We investigate the use of the Functional Capacity Index (FCI) as a tool for establishing vehicle safety priorities by comparing the life year burden of injuries to the burden of fatality in frontal and side automotive crashes. We demonstrate FCI's utility by investigating in detail the resulting disabling injuries and their life year costs. We selected occupants in the 2000-2013 NASS-CDS database involved in frontal and side crashes, merged their injuries with FCI, and then used the merged data to estimate each occupant's overall functional loss. Lifetime functional loss was assessed by combining this measure of impairment with the occupants' expected future life spans, estimated from the Social Security Administration's Actuarial Life Table. Frontal crashes produce a large number of disabling injuries, particularly to the lower extremities. In our population, these crashes are estimated to account for approximately 400,000 life years lost to disability in comparison with 500,000 life years lost to fatality. Victims of side crashes experienced a higher rate of fatality but a significantly lower rate of disabling injury (0.3 vs. 1.0%), resulting in approximately 370,000 life years lost to fatality versus 50,000 life years lost to disability. The burden of disabling injuries to car crash survivors should be considered when setting vehicle safety design priorities. In frontal crashes this burden in life years is similar to the burden attributable to fatality.

  7. Tensor representation techniques for full configuration interaction: A Fock space approach using the canonical product format.

    Science.gov (United States)

    Böhm, Karl-Heinz; Auer, Alexander A; Espig, Mike

    2016-06-28

    In this proof-of-principle study, we apply tensor decomposition techniques to the Full Configuration Interaction (FCI) wavefunction in order to approximate the wavefunction parameters efficiently and to reduce the overall computational effort. For this purpose, the wavefunction ansatz is formulated in an occupation number vector representation that ensures antisymmetry. If the canonical product format tensor decomposition is then applied, the Hamiltonian and the wavefunction can be cast into a multilinear product form. As a consequence, the number of wavefunction parameters does not scale to the power of the number of particles (or orbitals) but depends on the rank of the approximation and linearly on the number of particles. The degree of approximation can be controlled by a single threshold for the rank reduction procedure required in the algorithm. We demonstrate that using this approximation, the FCI Hamiltonian matrix can be stored with N(5) scaling. The error of the approximation that is introduced is below Millihartree for a threshold of ϵ = 10(-4) and no convergence problems are observed solving the FCI equations iteratively in the new format. While promising conceptually, all effort of the algorithm is shifted to the required rank reduction procedure after the contraction of the Hamiltonian with the coefficient tensor. At the current state, this crucial step is the bottleneck of our approach and even for an optimistic estimate, the algorithm scales beyond N(10) and future work has to be directed towards reduction-free algorithms.

  8. Steam explosion - physical foundations and relation to nuclear reactor safety

    International Nuclear Information System (INIS)

    Schumann, U.

    1982-08-01

    'Steam explosion' means the sudden evaporation of a fluid by heat exchange with a hotter material. Other terms are 'vapour explosion', 'thermal explosion', and 'energetic fuel-coolant interaction (FCI)'. In such an event a large fraction of the thermal energy initially stored in the hot material may possibly be converted into mechanical work. For pressurized water reactors one discusses (e.g. in risk analysis studies) a core melt-down accident during which molten fuel comes into contact with water. In the analysis of the consequences one has to investigate steam explosions. In this report an overview over the state of the knowledge is given. The overview is based on an extensive literature review. The objective of the report is to provide the basic knowledge which is required for understanding of the most important theories on the process of steam explosions. Following topics are treated: overview on steam explosion incidents, work potential, spontaneous nucleation, concept of detonation, results of some typical experiments, hydrodynamic fragmentation of drops, bubbles and jets, coarse mixtures, film-boiling, scenario of a core melt-down accident with possible steam-explosion in a pressurized water reactor. (orig.) [de

  9. Ankle torque steadiness is related to muscle activation variability and co-activation in children with cerebral palsy

    DEFF Research Database (Denmark)

    Bandholm, Thomas; Rose, Martin; Sløk, Rikke

    2009-01-01

    The aims of this study were to: (1) investigate the significance of muscle activation variability and coactivation for the ability to perform steady submaximal ankle torque (torque steadiness) in healthy children and those with cerebral palsy (CP), and (2) assess ankle function during isometric...... contractions in those children. Fourteen children with CP who walked with equinus foot deformity and 14 healthy (control) children performed maximal and steady submaximal ankle dorsi- and plantarflexions. Dorsiflexion torque steadiness was related to agonist and antagonist muscle activation variability as well...

  10. Effects of increasing the allowable compressive stress at release on the shear strength of prestressed concrete girders.

    Science.gov (United States)

    2008-09-01

    In recent years, several research projects have been conducted to study the feasibility of increasing the allowable : compressive stress in concrete at prestress transfer, currently defined as 0.60f'ci in the AASHTO LRFD Bridge : Design Specification...

  11. Performance on a Clinical Quadriceps Activation Battery Is Related to a Laboratory Measure of Activation and Recovery After Total Knee Arthroplasty.

    Science.gov (United States)

    Bade, Michael; Struessel, Tamara; Paxton, Roger; Winters, Joshua; Baym, Carol; Stevens-Lapsley, Jennifer

    2018-01-01

    To determine the relation between performance on a clinical quadriceps activation battery with (1) activation measured by doublet interpolation and (2) recovery of quadriceps strength and functional performance after total knee arthroplasty (TKA). Planned secondary analysis of a randomized controlled trial. University research laboratory. Patients (N=162; mean age, 63±7y; 89 women) undergoing TKA. Patients were classified as high (quadriceps activation battery ≥4/6) or low (quadriceps activation battery ≤3/6) based on performance on the quadriceps activation battery measured 4 days after TKA. Differences between groups in activation and recovery at 1, 2, 3, 6, and 12 months after TKA were compared using a repeated-measures maximum likelihood model. The low quadriceps activation battery group demonstrated poorer quadriceps activation via doublet interpolation (P=.01), greater quadriceps strength loss (P=.01), and greater functional performance decline (all Pbattery group. Differences between low and high quadriceps activation battery groups on all measures did not persist at 3 and 12 months (all P>.05). Poor performance on the quadriceps activation battery early after TKA is related to poor quadriceps activation and poor recovery in the early postoperative period. Patients in the low quadriceps activation battery group took 3 months to recover to the same level as the high quadriceps activation battery group. The quadriceps activation battery may be useful in identifying individuals who need specific interventions to target activation deficits or different care pathways in the early postoperative period to speed recovery after TKA. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  12. Threat-related amygdala activity is associated with peripheral CRP concentrations in men but not women

    Science.gov (United States)

    Swartz, Johnna R.; Prather, Aric A.; Hariri, Ahmad R.

    2017-01-01

    Increased levels of peripheral inflammatory markers, including C-Reactive Protein (CRP), are associated with increased risk for depression, anxiety, and suicidality. The brain mechanisms that may underlie the association between peripheral inflammation and internalizing problems remain to be determined. The present study examines associations between peripheral CRP concentrations and threat-related amygdala activity, a neural biomarker of depression and anxiety risk, in a sample of 172 young adult undergraduate students. Participants underwent functional MRI scanning while performing an emotional face matching task to obtain a measure of threat-related amygdala activity to angry and fearful faces; CRP concentrations were assayed from dried blood spots. Results indicated a significant interaction between CRP and sex: in men, but not women, higher CRP was associated with higher threat-related amygdala activity. These results add to the literature finding associations between systemic levels of inflammation and brain function and suggest that threat-related amygdala activity may serve as a potential pathway through which heightened chronic inflammation may increase risk for mood and anxiety problems. PMID:28183031

  13. Chapter 6: Children's Environmental Access in Relation to Motor Competence, Physical Activity, and Fitness

    Science.gov (United States)

    Erwin, Heather E.; Woods, Amelia Mays; Woods, Martha K.; Castelli, Darla M.

    2007-01-01

    The purpose of this study was to examine levels of physical activity engagement, motor competence, and physical fitness as related to child access to physical activity facilities in the home and school environments. The present investigation attempts to further efforts to examine the relationship between physical activity levels and access.…

  14. The contribution of former work-related activity levels to predict physical activity and sedentary time during early retirement: moderating role of educational level and physical functioning.

    Directory of Open Access Journals (Sweden)

    Delfien Van Dyck

    Full Text Available The transition to retirement introduces a decline in total physical activity and an increase in TV viewing time. Nonetheless, as more time becomes available, early retirement is an ideal stage to implement health interventions. Therefore, knowledge on specific determinants of physical activity and sedentary time is needed. Former work-related physical activity has been proposed as a potential determinant, but concrete evidence is lacking. The aim of this study was to examine if former work-related sitting, standing, walking or vigorous activities predict physical activity and sedentary time during early retirement. Additionally, moderating effects of educational level and physical functioning were examined.In total, 392 recently retired Belgian adults (>6 months, <5 years completed the International Physical Activity Questionnaire, the SF-36 Health Survey and a questionnaire on sociodemographics and former work-related activities. Generalized linear regression analyses were conducted in R. Moderating effects were examined by adding cross-products to the models.More former work-related sitting was predictive of more screen time during retirement. Lower levels of former work-related vigorous activities and higher levels of former work-related walking were associated with respectively more cycling for transport and more walking for transport during retirement. None of the predictors significantly explained passive transportation, cycling and walking for recreation, and leisure-time moderate-to-vigorous physical activity during retirement. Several moderating effects were found, but the direction of the interactions was not univocal.Former-work related behaviors are of limited importance to explain physical activity during early retirement, so future studies should focus on other individual, social and environmental determinants. Nonetheless, adults who previously had a sedentary job had higher levels of screen time during retirement, so this is an

  15. The contribution of former work-related activity levels to predict physical activity and sedentary time during early retirement: moderating role of educational level and physical functioning.

    Science.gov (United States)

    Van Dyck, Delfien; Cardon, Greet; Deforche, Benedicte; De Bourdeaudhuij, Ilse

    2015-01-01

    The transition to retirement introduces a decline in total physical activity and an increase in TV viewing time. Nonetheless, as more time becomes available, early retirement is an ideal stage to implement health interventions. Therefore, knowledge on specific determinants of physical activity and sedentary time is needed. Former work-related physical activity has been proposed as a potential determinant, but concrete evidence is lacking. The aim of this study was to examine if former work-related sitting, standing, walking or vigorous activities predict physical activity and sedentary time during early retirement. Additionally, moderating effects of educational level and physical functioning were examined. In total, 392 recently retired Belgian adults (>6 months, Physical Activity Questionnaire, the SF-36 Health Survey and a questionnaire on sociodemographics and former work-related activities. Generalized linear regression analyses were conducted in R. Moderating effects were examined by adding cross-products to the models. More former work-related sitting was predictive of more screen time during retirement. Lower levels of former work-related vigorous activities and higher levels of former work-related walking were associated with respectively more cycling for transport and more walking for transport during retirement. None of the predictors significantly explained passive transportation, cycling and walking for recreation, and leisure-time moderate-to-vigorous physical activity during retirement. Several moderating effects were found, but the direction of the interactions was not univocal. Former-work related behaviors are of limited importance to explain physical activity during early retirement, so future studies should focus on other individual, social and environmental determinants. Nonetheless, adults who previously had a sedentary job had higher levels of screen time during retirement, so this is an important subgroup to focus on during interventions

  16. In patients with neovascular age-related macular degeneration, physical activity may influence C-reactive protein levels

    DEFF Research Database (Denmark)

    Subhi, Yousif; Singh, Amardeep; Falk, Mads Krüger

    2014-01-01

    Association of neovascular age-related macular degeneration (AMD) with C-reactive protein (CRP) was previously reported, indicating a relation to systemic low-grade inflammation. However, visual impairment limits physical activity, and physical activity modulates CRP levels. Here, we investigated...

  17. Gender Differences in Both Force Concept Inventory and Introductory Physics Performance

    Science.gov (United States)

    Docktor, Jennifer; Heller, Kenneth

    2008-10-01

    We present data from a decade of introductory calculus-based physics courses for science and engineering students at the University of Minnesota taught using cooperative group problem solving. The data include 40 classes with more than 5500 students taught by 22 different professors. The average normalized gain for males is 0.4 for these large classes that emphasized problem solving. Female students made up approximately 20% of these classes. We present relationships between pre and post Force Concept Inventory (FCI) scores, course grades, and final exam scores for females and males. We compare our results with previous studies from Harvard [2] and the University of Colorado [3,4]. Our data show there is a significant gender gap in pre-test FCI scores that persists post-instruction although there is essentially no gender difference in course performance as determined by course grade.

  18. Mothers' Reading-Related Activities at Home and Learning to Read during Kindergarten

    Science.gov (United States)

    Silinskas, Gintautas; Parrila, Rauno; Lerkkanen, Marja-Kristiina; Poikkeus, Anna-Maija; Niemi, Pekka; Nurmi, Jari-Erik

    2010-01-01

    This longitudinal study investigates how the reading-related activities of mothers at home relate to the development of reading skills among their kindergarten children. A total of 1,529 children (5-to-6-year-olds) were tested on word reading twice, once at the beginning and once at the end of a kindergarten year. The mothers of the children (n =…

  19. 77 FR 38307 - Agency Information Collection Activities: Refugee/Asylee Relative Petition, Extension, Without...

    Science.gov (United States)

    2012-06-27

    ... Collection Activities: Refugee/Asylee Relative Petition, Extension, Without Change, of a Currently Approved Collection ACTION: 60-Day Notice of Information Collection Under Review: Form I- 730, Refugee/Asylee Relative...: Extension, without change, of a currently approved collection. (2) Title of the Form/Collection: Refugee...

  20. Seniority Number in Valence Bond Theory.

    Science.gov (United States)

    Chen, Zhenhua; Zhou, Chen; Wu, Wei

    2015-09-08

    In this work, a hierarchy of valence bond (VB) methods based on the concept of seniority number, defined as the number of singly occupied orbitals in a determinant or an orbital configuration, is proposed and applied to the studies of the potential energy curves (PECs) of H8, N2, and C2 molecules. It is found that the seniority-based VB expansion converges more rapidly toward the full configuration interaction (FCI) or complete active space self-consistent field (CASSCF) limit and produces more accurate PECs with smaller nonparallelity errors than its molecular orbital (MO) theory-based analogue. Test results reveal that the nonorthogonal orbital-based VB theory provides a reverse but more efficient way to truncate the complete active Hilbert space by seniority numbers.

  1. The perceived importance of physical activity: associations with psychosocial and health-related outcomes.

    Science.gov (United States)

    Wójcicki, Thomas R; Szabo, Amanda N; White, Siobhan M; Mailey, Emily L; Kramer, Arthur F; McAuley, Edward

    2013-03-01

    The purpose of this study was to assess the extent to which participation in a 12-month exercise program changed the degree of importance that older adults attached to physical activity. In addition, associations among changes in physical activity importance and health-related and psychosocial outcomes were examined. Community-dwelling older adults (N = 179) were recruited to participate in a 12-month exercise trial examining the association between changes in physical activity and fitness with changes in brain structure and psychological health. Participants were randomly assigned to a walking condition or a flexibility, toning, and balance condition. Physical, psychological, and cognitive assessments were taken at months 0, 6, and 12. Involvement in a 12-month exercise program increased the importance that participants placed on physical activity; this positive change was similar across exercise condition and sex. Changes in importance, however, were only associated with changes in physical health status and outcome expectations for exercise midway through the intervention. There were no significant associations at the end of the program. Regular participation in physical activity can positively influence the perceived importance of the behavior itself. Yet, the implications of such changes on physical activity-related outcomes remain equivocal and warrant further investigation.

  2. Some activities at CEA related to behaviour of core internals

    International Nuclear Information System (INIS)

    Petrequin, P.

    1998-01-01

    Eighteen transparencies where presented, elaborating some activities at CEA related to behaviour of core internals. After some introduction, ten of the transparencies are essentially a copy of the table of contents of the AMES report no. 11 (report no: EUR 17694 EN). The remaining 6 foils concerned themselves with irradiation experiments in test reactors, namely the IDAHO, CASIMIR and ALEXANDRA experiments

  3. Relation between flexor spasms, uninhibited detrusor contractions and anal sphincter activity

    DEFF Research Database (Denmark)

    Pedersen, E; Petersen, T; Schrøder, H D

    1986-01-01

    The time relation between flexor spasms, detrusor contractions and anal sphincter activity was recorded in a consecutive series of 111 patients with hyperreflexic bladder and flexor spasms. In 76 of the patients flexor spasms were preceded by detrusor contractions. The opposite pattern, namely de...

  4. Examining the effects of testwiseness in conceptual physics evaluations

    Science.gov (United States)

    DeVore, Seth; Stewart, John; Stewart, Gay

    2016-12-01

    Testwiseness is defined as the set of cognitive strategies used by a student that is intended to improve his or her score on a test regardless of the test's subject matter. Questions with elements that may be affected by testwiseness are common in physics assessments, even in those which have been extensively validated and widely used as evaluation tools in physics education research. The potential effect of several elements of testwiseness were analyzed for questions in the Force Concept Inventory (FCI) and Conceptual Survey on Electricity and Magnetism that contain distractors that are predicted to be influenced by testwiseness. This analysis was performed using data sets collected between fall 2001 and spring 2014 at one midwestern U.S. university (including over 9500 students) and between Spring 2011 and Spring 2015 at a second eastern U.S. university (including over 2500 students). Student avoidance of "none of the above" or "zero" distractors was statistically significant. The effect of the position of a distractor on its likelihood to be selected was also significant. The effects of several potential positive and negative testwiseness effects on student scores were also examined by developing two modified versions of the FCI designed to include additional elements related to testwiseness; testwiseness produced little effect post-instruction in student performance on the modified instruments.

  5. Analysis of work ability and work-related physical activity of employees in a medium-sized business.

    Science.gov (United States)

    Wilke, Christiane; Ashton, Philip; Elis, Tobias; Biallas, Bianca; Froböse, Ingo

    2015-12-18

    Work-related physical activity (PA) and work ability are of growing importance in modern working society. There is evidence for age- and job-related differences regarding PA and work ability. This study analyses work ability and work-related PA of employees in a medium-sized business regarding age and occupation. The total sample consists of 148 employees (116 men-78.38% of the sample-and 32 women, accounting for 21.62%; mean age: 40.85 ± 10.07 years). 100 subjects (67.57%) are white-collar workers (WC), and 48 (32.43%) are blue-collar workers (BC). Work ability is measured using the work ability index, and physical activity is obtained via the Global Physical Activity Questionnaire. Work ability shows significant differences regarding occupation (p = 0.001) but not regarding age. Further, significant differences are found for work-related PA concerning occupation (p Work ability is rated as good, yet, a special focus should lie on the promotion during early and late working life. Also, there is still a lack of evidence on the level of work-related PA. Considering work-related PA could add to meeting current activity recommendations.

  6. Seasonal variations in health-related human physical activity.

    Science.gov (United States)

    Reilly, Thomas; Peiser, Benny

    2006-01-01

    There are profound fluctuations in climate that occur within the annual cycle of seasonal changes. The severity of these changes depends on latitude of location and prevailing topography. Living creatures have evolved means of coping with seasonal extremes. Endogenous circannual cycles, at least in humans, appear to have been masked by mechanisms employed to cope with environmental changes. Physical activity levels tend to be lower in winter than in summer, mediating effects on health-related fitness. In athletes, seasonal changes are dictated by requirements of the annual programme of competitive engagements rather than an inherent circannual rhythm. Injury rates are influenced by seasonal environmental factors, notably in field sports. Season of birth has been related to susceptibility to selected morbidities, including mental ill-health. In age-restricted sports, there is a date-of-birth bias favouring those individuals born early in the competitive year. Trainers and selectors should acknowledge this trend if they are to avoid omitting gifted individuals, born later in the year, from talent development programmes.

  7. Seasonal bat activity related to insect emergence at three temperate lakes.

    Science.gov (United States)

    Salvarina, Ioanna; Gravier, Dorian; Rothhaupt, Karl-Otto

    2018-04-01

    Knowledge of aquatic food resources entering terrestrial systems is important for food web studies and conservation planning. Bats, among other terrestrial consumers, often profit from aquatic insect emergence and their activity might be closely related to such events. However, there is a lack of studies which monitor bat activity simultaneously with aquatic insect emergence, especially from lakes. Thus, our aim was to understand the relationship between insect emergence and bat activity, and investigate whether there is a general spatial or seasonal pattern at lakeshores. We assessed whole-night bat activity using acoustic monitoring and caught emerging and aerial flying insects at three different lakes through three seasons. We predicted that insect availability and seasonality explain the variation in bat activity, independent of the lake size and characteristics. Spatial (between lakes) differences of bat activity were stronger than temporal (seasonal) differences. Bat activity did not always correlate to insect emergence, probably because other factors, such as habitat characteristics, or bats' energy requirements, play an important role as well. Aerial flying insects explained bat activity better than the emerged aquatic insects in the lake with lowest insect emergence. Bats were active throughout the night with some activity peaks, and the pattern of their activity also differed among lakes and seasons. Lakes are important habitats for bats, as they support diverse bat communities and activity throughout the night and the year when bats are active. Our study highlights that there are spatial and temporal differences in bat activity and its hourly nocturnal pattern, that should be considered when investigating aquatic-terrestrial interactions or designing conservation and monitoring plans.

  8. Cancer-related fatigue and physical activity among premenopausal cervical and endometrial cancer survivors in Japan.

    Science.gov (United States)

    Obama, Kyoko; Maru, Mitsue; Maeda, Rumi; Kubota, Toshiro

    2015-09-30

    To examine the relationship between cancer-related fatigue (CRF) and physical activity in daily living in premenopausal disease-free cervical and endometrial cancer survivors. A physical activity monitor was used to collect objective data on daily physical activity. CRF and related variables were measured using self-report scales in a cross-sectional manner. The average age was 44.9 years among 64 women. The higher CRF group comprised 22 women (34%), 10% of whom had severe fatigue. The participants had higher physical activity levels compared with the findings in previous studies, and reported an average of 40 min/day of moderate to vigorous activity. Moderate to vigorous levels of physical activity were derived from essential social activities rather than leisure time exercise. There were no significant differences in physical activity levels between the lower and higher CRF groups. Our study results suggested that the higher level of physical activity in daily living itself had no relationship with decreasing CRF among premenopausal cervical and endometrial cancer survivors. It would be better to focus on cognitive and psychological factors before introducing physical activity programs and be careful of the characteristics of the participants' physical activity among this population in daily basis.

  9. Material effect in the fuel-coolant interaction: structural characterization of the steam explosion debris and solidification mechanism

    International Nuclear Information System (INIS)

    Tyrpekl, V.

    2012-01-01

    This work has been performed under joint supervision between Charles University in Prague (Czech Republic) and Strasbourg University (France). It also profited from the background and cooperation of Institute of Inorganic Chemistry Academy of Science of the Czech Republic and French Commission for Atomic and Alternative energies (CEA Cadarache). Results of the work contribute to the OECD/NEA project Serena 2 (Program on Steam Explosion Resolution for Nuclear Applications). Presented thesis can be classed in the scientific field of nuclear safety and material science. It is aimed on the so-called 'molten nuclear Fuel - Coolant Interaction' (FCI) that belongs among the recent issues of the nuclear reactor severe accident R and D. During the nuclear reactor melt down accident the melted reactor load can interact with the coolant (light water). This interaction can be located inside the vessel or outside in the case of vessel break-up. These two scenarios are commonly called in- and ex-vessel FCI and they differ in the conditions such as initial pressure of the system, water sub-cooling etc. The Molten fuel - coolant interaction can progress into thermal detonation called 'steam explosion' that can challenge the reactor or containment integrity. Recent experiments have shown that the melt composition has a major effect on the occurrence and yield of such explosion. In particular, different behaviors have been observed between simulant material (alumina), which has important explosion efficiency, and some prototypic corium compositions (80 w. % UO 2 , 20% w. % ZrO 2 . This 'material effect' has launched a new interest in the post-test analyses of FCI debris in order to estimate the processes occurring during these extremely rapid phenomena. The thesis is organized in nine chapters. The chapter 1 gives the general introduction and context of the nuclear reactor accident. Major nuclear accidents (Three Miles Island 1979, Chernobyl 1986 and Fukushima 2011) are briefly

  10. Environmental planning related to the oil industry activities at Maracaibo Lake Venezuela

    International Nuclear Information System (INIS)

    German, F.

    1993-01-01

    Maracaibo Lake has been the center of most of the hydrocarbon exploration and production activities in Venezuela since the early twenties, with a total cumulative oil extraction of nearly 40 billion barrels. The intensive activities related to production have brought a wide variety of ecosystem perturbations, as a consequence of the construction of facilities for exploration, transport, treatment, storage, and oil refining, as well as the generation of effluents, emissions, and solid wastes therein associated. The Venezuelan Petroleum Corporation (PDVSA) has recognized the importance of preventing further potential damage from its current operations and future expansions, with an additional concern for restoring affected areas. Herein, actual and future restoration/mitigation environmental planning will be discussed, emphasizing a research program focused on the Maracaibo Lake region, being conducted by PDVSA's R ampersand D Corporative branch. Research main objective is to gather, for PDVSA operating companies, a priority setting, as a function of environmental or ecological risks, related to the oil industry activities. To this end, efforts will be directed from a multidisciplinary approach, taking into account some of the major links structuring ecosystem complexity

  11. Prevalence of factors related to active reproductive health behavior: a cross-sectional study Indonesian adolescent

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    Tantut Susanto

    2016-09-01

    Full Text Available OBJECTIVES Complex and diverse factors are related to reproductive health (RH behavior among adolescents according to the social and cultural context of each countries. This study examined the prevalence of active RH and factors related to active RH behavior among Indonesian adolescents. METHODS A cross-sectional study was conducted among 1,040 of students who were selected through a multi-stage random sampling technique. A self-administered questionnaire was developed, including the World Health Organization Illustrative Questionnaire for Interview-Surveys with Young People, pubertal development scale, and sexual activity scale, modified in accordance to the Indonesian context. The data were analyzed using descriptive and comparative statistics, as well as logistic regression analyses. RESULTS The prevalence of active RH behavior were more higher in boys (56.6%; 95% confidence interval [CI], 50.6% to 62.6% than in girls (43.7%; 95% CI, 37.6% to 49.8%. Negative attitudes towards RH were a factor related to active RH behavior in both boys and girls. Smoking and kind relationship envisioned before marriage (pacaran [courtship] and nikah siri [non-registered marriage] were factors related to active RH behavior in boys; whereas the absence of access to information on substance abuse was an additional factor in girls. Moreover, an interaction was found between access to information on development and smoking (boys and attitudes on RH (girls as independent variables associated with active RH behavior. CONCLUSIONS Sex education for adolescents in Indonesia, particularly in the context of a health promotion program, should be developed based on prevalent social, cultural, and religious values to prevent active RH behavior. Such programs should focus on the kind of relationship envisioned before marriage and smoking for boys and access to information on subtance abuse for girls.

  12. Modulating Estrogen Receptor-related Receptor-α Activity Inhibits Cell Proliferation*

    OpenAIRE

    Bianco, Stéphanie; Lanvin, Olivia; Tribollet, Violaine; Macari, Claire; North, Sophie; Vanacker, Jean-Marc

    2009-01-01

    High expression of the estrogen receptor-related receptor (ERR)-α in human tumors is correlated to a poor prognosis, suggesting an involvement of the receptor in cell proliferation. In this study, we show that a synthetic compound (XCT790) that modulates the activity of ERRα reduces the proliferation of various cell lines and blocks the G1/S transition of the cell cycle in an ERR...

  13. Conflict-related activity in the caudal anterior cingulate cortex in the absence of awareness

    Science.gov (United States)

    Ursu, Stefan; Clark, Kristi A.; Aizenstein, Howard J.; Stenger, V. Andrew; Carter, Cameron S.

    2009-01-01

    The caudal anterior cingulate cortex (cACC) is thought to be involved in performance monitoring, as conflict and error-related activity frequently co-localize in this area. Recent results suggest that these effects may be differentially modulated by awareness. To clarify the role of awareness in performance monitoring by the cACC, we used rapid event-related fMRI to examine the cACC activity while subjects performed a dual task: a delayed recognition task and a serial response task (SRT) with an implicit probabilistic learning rule (i.e. the stimulus location followed a probabilistic sequence of which the subjects were unaware). Task performance confirmed that the location sequence was learned implicitly. Even though we found no evidence of awareness for the presence of the sequence, imaging data revealed increased cACC activity during correct trials which violated the sequence (high conflict), relative to trials when stimuli followed the sequence (low conflict). Errors made with awareness also activated the same brain region. These results suggest that the performance monitoring function of the cACC extends beyond detection of errors made with or without awareness, and involves detection of multiple responses even when they are outside of awareness. PMID:19026710

  14. Effect of Relative Humidity on Adsorption Breakthrough of CO2 on Activated Carbon Fibers

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    Yu-Chun Chiang

    2017-11-01

    Full Text Available Microporous activated carbon fibers (ACFs were developed for CO2 capture based on potassium hydroxide (KOH activation and tetraethylenepentamine (TEPA amination. The material properties of the modified ACFs were characterized using several techniques. The adsorption breakthrough curves of CO2 were measured and the effect of relative humidity in the carrier gas was determined. The KOH activation at high temperature generated additional pore networks and the intercalation of metallic K into the carbon matrix, leading to the production of mesopore and micropore volumes and providing access to the active sites in the micropores. However, this treatment also resulted in the loss of nitrogen functionalities. The TEPA amination has successfully introduced nitrogen functionalities onto the fiber surface, but its long-chain structure blocked parts of the micropores and, thus, made the available surface area and pore volume limited. Introduction of the power of time into the Wheeler equation was required to fit the data well. The relative humidity within the studied range had almost no effects on the breakthrough curves. It was expected that the concentration of CO2 was high enough so that the impact on CO2 adsorption capacity lessened due to increased relative humidity.

  15. Spinal activation of alpha7-nicotinic acetylcholine receptor attenuates posttraumatic stress disorder-related chronic pain via suppression of glial activation.

    Science.gov (United States)

    Sun, Rao; Zhang, Wei; Bo, Jinhua; Zhang, Zuoxia; Lei, Yishan; Huo, Wenwen; Liu, Yue; Ma, Zhengliang; Gu, Xiaoping

    2017-03-06

    The high prevalence of chronic pain in posttraumatic stress disorder (PTSD) individuals has been widely reported by clinical studies, which emphasized an urgent need to uncover the underlying mechanisms and identify potential therapeutic targets. Recent studies suggested that targeting activated glia and their pro-inflammatory products may provide a novel and effective therapy for the stress-related pain. In this study, we investigated whether activation of alpha-7 nicotinic acetylcholine receptor (α7 nAChR), a novel anti-inflammatory target, could attenuate PTSD-related chronic pain. The experiments were conducted in a rat model of single prolonged stress (SPS), an established model of PTSD-pain comorbidity. We found that SPS exposure produced persistent mechanical allodynia. Immunohistochemical and enzyme-linked immuno sorbent assay analysis showed that SPS also induced elevated activation of glia cells (including microglia and astrocytes) and accumulation of pro-inflammatory cytokines in spinal cord. In another experiment, we found that intrathecal injection of PHA-543613, a selective α7 nAchR agonist, attenuated the SPS-evoked allodynia in a dose dependent manner. However, this anti-hyperalgesic effect was blocked by pretreatment with methyllycaconitine (MLA), a selective α7 nAchR antagonist. Further analyses showed that PHA-543613 suppressed SPS-induced spinal glial activation and SPS-elevated spinal pro-inflammatory cytokines, and these were abolished by MLA. Taken together, the present study showed that spinal activation of α7 nAChR by PHA-543613 attenuated mechanical allodynia induced by PTSD-like stress, and the suppression of spinal glial activation may underlie this anti-hyperalgesic effect. Our study demonstrated the therapeutic potential of targeting α7 nAChR in the treatment of PTSD-related chronic pain. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

  16. Factors affecting the reproductive traits of Holstein cows

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    Daniella Flavia Vilas Boas

    2012-12-01

    Full Text Available For dairy cattle breeds, mainly the taurine ones, the selection emphasized for many years the increase in milk yields and, as a consequence, the adaptive and reproductive traits were negatively affected. The aim of this study was to verify the influence of genetic and environmental effects on the reproductive traits in a dairy herd selected for high milk production levels. The data set comprised 1,737 first lactations Holsteins cows of Agrindus Farm, located at Southeastern region of Brazil. The records of the following reproductive traits: calving to first heat interval (CFHI, calving to conception interval (CCI and first to second calving interval (FCI were analyzed as dependent variables by least squares method using GLM procedure (SAS. Linear models were considered including two production levels (1= less than 9,500 kg and 2= more than 9,501 kg of total milk yield, contemporary group (year and months calving, management group, sire of cow, and the sire used to breeding cows, as classificatory variables. As covariates were included for all traits the peak milk yield in lactation (linear effect, age at calving only for CFHI (linear and quadratic effects since this effect was not significant for other traits, and CFHI (linear effect only for FCI. The coefficients of determination represented 24%, 74% and 75%, respectively for CFHI, FCI and CCI models. Production level, peak milk yield and sire effects were significant (P<0.05 for all traits. The average estimated for high and low milk production level were 73 and 79 days, 500 and 601 days, 227 and 330 days for CFHI, FCI and CCI, respectively, suggesting that cows with higher genetic potential for milk had worse reproductive performance. Similarly, lactation peak showed significant effect (P<0.05 for all traits, suggesting higher peaks cows showed also poorer reproductive rates. Sire effect also was a variable that showed significant effect (P<0.01 for all traits, which means that there was

  17. 31 CFR 575.207 - Prohibited transactions relating to travel to Iraq or to activities within Iraq.

    Science.gov (United States)

    2010-07-01

    ... or Iraq; (b) Relating to travel and activities for the conduct of the official business of the United... travel to Iraq or to activities within Iraq. 575.207 Section 575.207 Money and Finance: Treasury... TREASURY IRAQI SANCTIONS REGULATIONS Prohibitions § 575.207 Prohibited transactions relating to travel to...

  18. Relative phase asynchrony and long-range correlation of long-term solar magnetic activity

    Science.gov (United States)

    Deng, Linhua

    2017-07-01

    Statistical signal processing is one of the most important tasks in a large amount of areas of scientific studies, such as astrophysics, geophysics, and space physics. Phase recurrence analysis and long-range persistence are the two dynamical structures of the underlying processes for the given natural phenomenon. Linear and nonlinear time series analysis approaches (cross-correlation analysis, cross-recurrence plot, wavelet coherent transform, and Hurst analysis) are combined to investigate the relative phase interconnection and long-range correlation between solar activity and geomagnetic activity for the time interval from 1932 January to 2017 January. The following prominent results are found: (1) geomagnetic activity lags behind sunspot numbers with a phase shift of 21 months, and they have a high level of asynchronous behavior; (2) their relative phase interconnections are in phase for the periodic scales during 8-16 years, but have a mixing behavior for the periodic belts below 8 years; (3) both sunspot numbers and geomagnetic activity can not be regarded as a stochastic phenomenon because their dynamical behaviors display a long-term correlation and a fractal nature. We believe that the presented conclusions could provide further information on understanding the dynamical coupling of solar dynamo process with geomagnetic activity variation, and the crucial role of solar and geomagnetic activity in the long-term climate change.

  19. Stages of Physical Activity Change and Health-Related Quality of Life among Students

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    Hossein Mozafar Saadati

    2015-08-01

    Full Text Available ​Background and objectives : Health-related quality of life encompasses the perception of valued characteristics of health such as well being and a feeling of comfort. The purpose of this study was to investigate the effect of individuals’ physical activity level on their quality of life. Material and Methods : This was a descriptive-analytic study. The studied sample consisted of 404 high school boys and girls of the district 1 of Qom city. The tools used in the research included self-administered questionnaire regarding quality of life, the process of changing physical activity and demographic variables. SPSS18, ANOVA test and descriptive statistics were applied for analysis. Results: In this study, regarding the stages of change for physical activity, 41.2% of the students were in the pre-contemplation and contemplation stages, in which this variable showed a significant correlation with students’ quality of life. More physically active individuals had a better quality of life (p Conclusion : To make a decision for doing physical activity and to do exercises, have positive and decisive impact on health-related quality of life; therefore, it is recommended that necessary trainings are given to students to modify and strengthen their attitudes toward physical activity. Also, sport facilities should be provided in natural environments through government-organized planning.

  20. The Relation of Personality Traits Wth Depression Severity in Active and Non-Active Elderly Women in Tehran City

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    Mohammad Ali Aslankhani

    2010-07-01

    Full Text Available Objectives: The purpose of this study was to investigate the relation of personality traits with depression in active and non – active elderly women in Tehran city. Methods & Materials: The present research is descriptive–correlation. For this purpose, 188 elderly women (94 active and 94 non - active elders in the age range of 63-82 in Tehran city availably selected as statistical sample. Measurement instrument were demographic questionnaire, Beck depression questionnaire and NEO personality traits questionnaire. Data were analyzed using descriptive statistic (mean and standard deviation and inferential statistic (independent t test, Pearson correlation and Enter multi variant Regression. Results: Results showed that there was significant difference in personality traits and depression between active women with non-active women elders (P<0.05. Also, the result showed that significant correlation between depression score on neuroticism, extroversion, openness and conscientiousness in active women elders and conscientiousness and openness in non-active women elders (P<0.05. The results of multi variant regression also indicated that openness and extroversion variants in active elders and conscientiousness variant in non-active elders have linear relationship with criteria variant (depression and can predict its changes. Conclusion: Based on results of present research, sport and physical activity can be afforded the increase of positive personality traits (for example extroversion and openness and decrease of depression in women elders.

  1. Higher Language Ability is Related to Angular Gyrus Activation Increase During Semantic Processing, Independent of Sentence Incongruency

    Science.gov (United States)

    Van Ettinger-Veenstra, Helene; McAllister, Anita; Lundberg, Peter; Karlsson, Thomas; Engström, Maria

    2016-01-01

    This study investigates the relation between individual language ability and neural semantic processing abilities. Our aim was to explore whether high-level language ability would correlate to decreased activation in language-specific regions or rather increased activation in supporting language regions during processing of sentences. Moreover, we were interested if observed neural activation patterns are modulated by semantic incongruency similarly to previously observed changes upon syntactic congruency modulation. We investigated 27 healthy adults with a sentence reading task—which tapped language comprehension and inference, and modulated sentence congruency—employing functional magnetic resonance imaging (fMRI). We assessed the relation between neural activation, congruency modulation, and test performance on a high-level language ability assessment with multiple regression analysis. Our results showed increased activation in the left-hemispheric angular gyrus extending to the temporal lobe related to high language ability. This effect was independent of semantic congruency, and no significant relation between language ability and incongruency modulation was observed. Furthermore, there was a significant increase of activation in the inferior frontal gyrus (IFG) bilaterally when the sentences were incongruent, indicating that processing incongruent sentences was more demanding than processing congruent sentences and required increased activation in language regions. The correlation of high-level language ability with increased rather than decreased activation in the left angular gyrus, a region specific for language processing, is opposed to what the neural efficiency hypothesis would predict. We can conclude that no evidence is found for an interaction between semantic congruency related brain activation and high-level language performance, even though the semantic incongruent condition shows to be more demanding and evoking more neural activation. PMID

  2. Higher language ability is related to angular gyrus activation increase during semantic processing, independent of sentence incongruency

    Directory of Open Access Journals (Sweden)

    Helene eVan Ettinger-Veenstra

    2016-03-01

    Full Text Available This study investigates the relation between individual language ability and neural semantic processing abilities. Our aim was to explore whether high-level language ability would correlate to decreased activation in language-specific regions or rather increased activation in supporting language regions during processing of sentences. Moreover, we were interested if observed neural activation patterns are modulated by semantic incongruency similarly to previously observed changes upon syntactic congruency modulation. We investigated 27 healthy adults with a sentence reading task - which tapped language comprehension and inference, and modulated sentence congruency - employing functional magnetic resonance imaging. We assessed the relation between neural activation, congruency modulation, and test performance on a high-level language ability assessment with multiple regression analysis. Our results showed increased activation in the left-hemispheric angular gyrus extending to the temporal lobe related to high language ability. This effect was independent of semantic congruency, and no significant relation between language ability and incongruency modulation was observed. Furthermore, a significant increase of activation in the inferior frontal gyrus bilaterally when the sentences were incongruent, indicating that processing incongruent sentences was more demanding than processing congruent sentences and required increased activation in language regions. The correlation of high-level language ability with increased rather than decreased activation in the left angular gyrus, a region specific for language processing is opposed to what the neural efficiency hypothesis would predict. We can conclude that there is no evidence found for an interaction between semantic congruency related brain activation and high-level language performance, even though the semantic incongruent condition shows to be more demanding and evoking more neural activation.

  3. Youth at risk of physical inactivity may benefit more from activity-related support than youth not at risk

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    Schmalz Dorothy L

    2006-03-01

    Full Text Available Background This study examines whether associations between activity-related support and adolescents' physical activity differ for adolescents at high versus low risk of physical inactivity. Methods: Participants included 202 middle-school-aged girls (N = 92 and boys (N = 110. Physical activity was assessed using three self-report questionnaires. Activity-related support from mothers, fathers, siblings, and peers was assessed using the Activity Support Scale. Perceived sport competence was assessed using the Physical Activity Self Description Questionnaire. Participants' height and weight were measured and used to calculate their age- and sex-adjusted Body Mass Index percentile. Participants were classified as being at high risk for physical inactivity if they fulfilled two of the following three criteria: (1 overweight; (2 female; or (3 having low perceived sport competence. Results: Activity-related support from all sources was associated with higher levels of physical activity among adolescents. A stronger association between activity support and physical activity was found for adolescents at high risk for physical inactivity in comparison to adolescents at low risk. Conclusions: Findings from this study suggest that the activity-related support from family and friends may be an effective tool in promoting physical activity among youth at risk of physical inactivity.

  4. [Antibacterial and anti-hemolysin activities of tea catechins and their structural relatives].

    Science.gov (United States)

    Toda, M; Okubo, S; Ikigai, H; Shimamura, T

    1990-03-01

    Among catechins tested, (-)epigallocatechin (EGC), (-)epicatechin gallate (ECg), (-) epigallocatechin gallate (EGCg) inhibited the growth of Staphylococcus aureus, Vibrio cholerae O1 classical Inaba 569B and El Tor Inaba V86. S. aureus was more sensitive than V. cholerae O1 to these compounds. EGCg showed also a bactericidal activity against V. cholerae O1 569B. Pyrogallol showed a stronger antibacterial activity against S. aureus and V. cholerae O1 than tannic and gallic acid. Rutin or caffein had no effect on them. ECg and EGCg showed the most potent anti-hemolysin activity against S. aureus alpha-toxin, Vibrio parahaemolyticus thermostable direct hemolysin (Vp-TDH) and cholera hemolysin. Among catechin relatives, only tannic acid had a potent anti-hemolysin activity against alpha-toxin. These results suggest that the catechol and pyrogallol groups are responsible for the antibacterial and bactericidal activities, while the conformation of catechins might play an important role in the anti-hemolysin activity.

  5. Stress-related methylation of the catechol-O-methyltransferase Val 158 allele predicts human prefrontal cognition and activity.

    Science.gov (United States)

    Ursini, Gianluca; Bollati, Valentina; Fazio, Leonardo; Porcelli, Annamaria; Iacovelli, Luisa; Catalani, Assia; Sinibaldi, Lorenzo; Gelao, Barbara; Romano, Raffaella; Rampino, Antonio; Taurisano, Paolo; Mancini, Marina; Di Giorgio, Annabella; Popolizio, Teresa; Baccarelli, Andrea; De Blasi, Antonio; Blasi, Giuseppe; Bertolino, Alessandro

    2011-05-04

    DNA methylation at CpG dinucleotides is associated with gene silencing, stress, and memory. The catechol-O-methyltransferase (COMT) Val(158) allele in rs4680 is associated with differential enzyme activity, stress responsivity, and prefrontal activity during working memory (WM), and it creates a CpG dinucleotide. We report that methylation of the Val(158) allele measured from peripheral blood mononuclear cells (PBMCs) of Val/Val humans is associated negatively with lifetime stress and positively with WM performance; it interacts with stress to modulate prefrontal activity during WM, such that greater stress and lower methylation are related to reduced cortical efficiency; and it is inversely related to mRNA expression and protein levels, potentially explaining the in vivo effects. Finally, methylation of COMT in prefrontal cortex and that in PBMCs of rats are correlated. The relationship of methylation of the COMT Val(158) allele with stress, gene expression, WM performance, and related brain activity suggests that stress-related methylation is associated with silencing of the gene, which partially compensates the physiological role of the high-activity Val allele in prefrontal cognition and activity. Moreover, these results demonstrate how stress-related DNA methylation of specific functional alleles impacts directly on human brain physiology beyond sequence variation.

  6. Lipoxin Generation Is Related to Soluble Epoxide Hydrolase Activity in Severe Asthma

    Science.gov (United States)

    Ono, Emiko; Dutile, Stefanie; Kazani, Shamsah; Wechsler, Michael E.; Yang, Jun; Hammock, Bruce D.; Douda, David Nobuhiro; Tabet, Yacine; Khaddaj-Mallat, Rayan; Sirois, Marco; Sirois, Chantal; Rizcallah, Edmond; Rousseau, Éric; Martin, Richard; Sutherland, E. Rand; Castro, Mario; N. Jarjour, Nizar; Israel, Elliot

    2014-01-01

    Rationale: Severe asthma is characterized by airway inflammatory responses associated with aberrant metabolism of arachidonic acid. Lipoxins (LX) are arachidonate-derived pro-resolving mediators that are decreased in severe asthma, yet mechanisms for defective LX biosynthesis and a means to increase LXs in severe asthma remain to be established. Objectives: To determine if oxidative stress and soluble epoxide hydrolase (sEH) activity are linked to decreased LX biosynthesis in severe asthma. Methods: Aliquots of blood, sputum, and bronchoalveolar lavage fluid were obtained from asthma subjects for mediator determination. Select samples were exposed to t-butyl-hydroperoxide or sEH inhibitor (sEHI) before activation. Peripheral blood leukocyte–platelet aggregates were monitored by flow cytometry, and bronchial contraction was determined with cytokine-treated human lung sections. Measurements and Main Results: 8-Isoprostane levels in sputum supernatants were inversely related to LXA4 in severe asthma (r = −0.55; P = 0.03) and t-butyl-hydroperoxide decreased LXA4 and 15-epi-LXA4 biosynthesis by peripheral blood leukocytes. LXA4 and 15-epi-LXA4 levels were inversely related to sEH activity in sputum supernatants and sEHIs significantly increased 14,15-epoxy-eicosatrienoic acid and 15-epi-LXA4 generation by severe asthma whole blood and bronchoalveolar lavage fluid cells. The abundance of peripheral blood leukocyte–platelet aggregates was related to asthma severity. In a concentration-dependent manner, LXs significantly inhibited platelet-activating factor–induced increases in leukocyte–platelet aggregates (70.8% inhibition [LXA4 100 nM], 78.3% inhibition [15-epi-LXA4 100 nM]) and 15-epi-LXA4 markedly inhibited tumor necrosis factor-α–induced increases in bronchial contraction. Conclusions: LX levels were decreased by oxidative stress and sEH activity. Inhibitors of sEH increased LXs that mediated antiphlogistic actions, suggesting a new therapeutic approach

  7. Toward equity through participation in Modeling Instruction in introductory university physics

    Science.gov (United States)

    Brewe, Eric; Sawtelle, Vashti; Kramer, Laird H.; O'Brien, George E.; Rodriguez, Idaykis; Pamelá, Priscilla

    2010-06-01

    We report the results of a five year evaluation of the reform of introductory calculus-based physics by implementation of Modeling Instruction (MI) at Florida International University (FIU), a Hispanic-serving institution. MI is described in the context of FIU’s overall effort to enhance student participation in physics and science broadly. Our analysis of MI from a “participationist” perspective on learning identifies aspects of MI including conceptually based instruction, culturally sensitive instruction, and cooperative group learning, which are consistent with research on supporting equitable learning and participation by students historically under-represented in physics (i.e., Black, Hispanic, women). This study uses markers of conceptual understanding as measured by the Force Concept Inventory (FCI) and odds of success as measured by the ratio of students completing introductory physics and earning a passing grade (i.e., C- or better) by students historically under-represented in physics to reflect equity and participation in introductory physics. FCI pre and post scores for students in MI are compared with lecture-format taught students. Modeling Instruction students outperform students taught in lecture-format classes on post instruction FCI (61.9% vs 47.9%, p<0.001 ), where these benefits are seen across both ethnic and gender comparisons. In addition, we report that the odds of success in MI are 6.73 times greater than in lecture instruction. Both odds of success and FCI scores within Modeling Instruction are further disaggregated by ethnicity and by gender to address the question of equity within the treatment. The results of this disaggregation indicate that although ethnically under-represented students enter with lower overall conceptual understanding scores, the gap is not widened during introductory physics but instead is maintained, and the odds of success for under-represented students is not different from majority students. Women

  8. Toward equity through participation in Modeling Instruction in introductory university physics

    Directory of Open Access Journals (Sweden)

    Eric Brewe

    2010-05-01

    Full Text Available We report the results of a five year evaluation of the reform of introductory calculus-based physics by implementation of Modeling Instruction (MI at Florida International University (FIU, a Hispanic-serving institution. MI is described in the context of FIU’s overall effort to enhance student participation in physics and science broadly. Our analysis of MI from a “participationist” perspective on learning identifies aspects of MI including conceptually based instruction, culturally sensitive instruction, and cooperative group learning, which are consistent with research on supporting equitable learning and participation by students historically under-represented in physics (i.e., Black, Hispanic, women. This study uses markers of conceptual understanding as measured by the Force Concept Inventory (FCI and odds of success as measured by the ratio of students completing introductory physics and earning a passing grade (i.e., C− or better by students historically under-represented in physics to reflect equity and participation in introductory physics. FCI pre and post scores for students in MI are compared with lecture-format taught students. Modeling Instruction students outperform students taught in lecture-format classes on post instruction FCI (61.9% vs 47.9%, p<0.001, where these benefits are seen across both ethnic and gender comparisons. In addition, we report that the odds of success in MI are 6.73 times greater than in lecture instruction. Both odds of success and FCI scores within Modeling Instruction are further disaggregated by ethnicity and by gender to address the question of equity within the treatment. The results of this disaggregation indicate that although ethnically under-represented students enter with lower overall conceptual understanding scores, the gap is not widened during introductory physics but instead is maintained, and the odds of success for under-represented students is not different from majority students

  9. Phosphatase activity in relation to key litter and soil properties in mature subtropical forests in China.

    Science.gov (United States)

    Hou, Enqing; Chen, Chengrong; Wen, Dazhi; Liu, Xian

    2015-05-15

    Phosphatase-mediated phosphorus (P) mineralization is one of the critical processes in biogeochemical cycling of P and determines soil P availability in forest ecosystems; however, the regulation of soil phosphatase activity remains elusive. This study investigated the potential extracellular activities of acid phosphomonoesterase (AcPME) and phosphodiesterase (PDE) and how they were related to key edaphic properties in the L horizon (undecomposed litter) and F/H horizon (fermented and humified litter) and the underlying mineral soil at the 0-15cm depth in eight mature subtropical forests in China. AcPME activity decreased significantly in the order of F/H horizon>L horizon>mineral soil horizon, while the order for PDE activity was L horizon=F/H horizon>mineral soil horizon. AcPME (X axis) and PDE (Y axis) activities were positively correlated in all horizons with significantly higher slope in the L and F/H horizons than in the mineral soil horizon. Both AcPME and PDE activities were positively related to microbial biomass C, moisture content and water-holding capacity in the L horizon, and were positively related to soil C:P, N:P and C:N ratios and fine root (diameter≤2mm) biomass in the mineral soil horizon. Both enzyme activities were also interactively affected by forest and horizon, partly due to the interactive effect of forest and horizon on microbial biomass. Our results suggest that modulator(s) of the potential extracellular activity of phosphatases vary with horizon, depending on the relative C, P and water availability of the horizon. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Effects of V4c-ICL Implantation on Myopic Patients’ Vision-Related Daily Activities

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    Taixiang Liu

    2016-01-01

    Full Text Available The new type implantable Collamer lens with a central hole (V4c-ICL is widely used to treat myopia. However, halos occur in some patients after surgery. The aim is to evaluate the effect of V4c-ICL implantation on vision-related daily activities. This retrospective study included 42 patients. Uncorrected visual acuity (UCVA, best corrected visual acuity (BCVA, intraocular pressure (IOP, endothelial cell density (ECD, and vault were recorded and vision-related daily activities were evaluated at 3 months after operation. The average spherical equivalent was -0.12±0.33 D at 3 months after operation. UCVA equal to or better than preoperative BCVA occurred in 98% of eyes. The average BCVA at 3 months after operation was -0.03±0.07 LogMAR, which was significantly better than preoperative BCVA (0.08±0.10 LogMAR (P=0.029. Apart from one patient (2.4% who had difficulty reading computer screens, all patients had satisfactory or very satisfactory results. During the early postoperation, halos occurred in 23 patients (54.8%. However there were no significant differences in the scores of visual functions between patients with and without halos (P>0.05. Patients were very satisfied with their vision-related daily activities at 3 months after operation. The central hole of V4c-ICL does not affect patients’ vision-related daily activities.

  11. Sex Commonalities and Differences in Obesity-Related Alterations in Intrinsic Brain Activity and Connectivity.

    Science.gov (United States)

    Gupta, Arpana; Mayer, Emeran A; Labus, Jennifer S; Bhatt, Ravi R; Ju, Tiffany; Love, Aubrey; Bal, Amanat; Tillisch, Kirsten; Naliboff, Bruce; Sanmiguel, Claudia P; Kilpatrick, Lisa A

    2018-02-01

    This study aimed to characterize obesity-related sex differences in the intrinsic activity and connectivity of the brain's reward networks. Eighty-six women (n = 43) and men (n = 43) completed a 10-minute resting functional magnetic resonance imaging scan. Sex differences and commonalities in BMI-related frequency power distribution and reward seed-based connectivity were investigated by using partial least squares analysis. For whole-brain activity in both men and women, increased BMI was associated with increased slow-5 activity in the left globus pallidus (GP) and substantia nigra. In women only, increased BMI was associated with increased slow-4 activity in the right GP and bilateral putamen. For seed-based connectivity in women, increased BMI was associated with reduced slow-5 connectivity between the left GP and putamen and the emotion and cortical regulation regions, but in men, increased BMI was associated with increased connectivity with the medial frontal cortex. In both men and women, increased BMI was associated with increased slow-4 connectivity between the right GP and bilateral putamen and the emotion regulation and sensorimotor-related regions. The stronger relationship between increased BMI and decreased connectivity of core reward network components with cortical and emotion regulation regions in women may be related to the greater prevalence of emotional eating. The present findings suggest the importance of personalized treatments for obesity that consider the sex of the affected individual. © 2017 The Obesity Society.

  12. Associations of physical activity with driving-related cognitive abilities in older drivers: an exploratory study.

    Science.gov (United States)

    Marmeleira, José; Ferreira, Inês; Melo, Filipe; Godinho, Mário

    2012-10-01

    The purpose of this study was to examine the associations between hysical activity and driving-related cognitive abilities of older drivers. Thirty-eight female and male drivers ages 61 to 81 years (M = 70.2, SD = 5.0) responded to the International Physical Activity Questionnaire and were assessed on a battery of neuropsychological tests, which included measures of visual attention, executive functioning, mental status, visuospatial ability, and memory. A higher amount of reported physical activity was significantly correlated with better scores on tests of visual processing speed and divided visual attention. Higher amounts of physical activity was significantly associated with a better composite score for visual attention, but its correlation with the composite score for executive functioning was not significant. These findings support the hypothesis that pzhysical activity is associated with preservation of specific driving-related cognitive abilities of older adults.

  13. Database and Related Activities in Japan

    International Nuclear Information System (INIS)

    Murakami, Izumi; Kato, Daiji; Kato, Masatoshi; Sakaue, Hiroyuki A.; Kato, Takako; Ding, Xiaobin; Morita, Shigeru; Kitajima, Masashi; Koike, Fumihiro; Nakamura, Nobuyuki; Sakamoto, Naoki; Sasaki, Akira; Skobelev, Igor; Tsuchida, Hidetsugu; Ulantsev, Artemiy; Watanabe, Tetsuya; Yamamoto, Norimasa

    2011-01-01

    We have constructed and made available atomic and molecular (AM) numerical databases on collision processes such as electron-impact excitation and ionization, recombination and charge transfer of atoms and molecules relevant for plasma physics, fusion research, astrophysics, applied-science plasma, and other related areas. The retrievable data is freely accessible via the internet. We also work on atomic data evaluation and constructing collisional-radiative models for spectroscopic plasma diagnostics. Recently we have worked on Fe ions and W ions theoretically and experimentally. The atomic data and collisional-radiative models for these ions are examined and applied to laboratory plasmas. A visible M1 transition of W 26+ ion is identified at 389.41 nm by EBIT experiments and theoretical calculations. We have small non-retrievable databases in addition to our main database. Recently we evaluated photo-absorption cross sections for 9 atoms and 23 molecules and we present them as a new database. We established a new association ''Forum of Atomic and Molecular Data and Their Applications'' to exchange information among AM data producers, data providers and data users in Japan and we hope this will help to encourage AM data activities in Japan.

  14. Marine benthic faunal successional stages and related sedimentary activity

    Directory of Open Access Journals (Sweden)

    Rutger Rosenberg

    2001-12-01

    Full Text Available This paper is a brief review of successional stages and activity of benthic soft-bottom communities. Benthic communities was first described by Petersen in the 1910s and further developed by Molander, Thorson and Margalef. Successional stages of benthic communities chance in a predictable way in relation to environmental disturbance and food availability. Food supply to the bottom can occur as a vertical flux, but transport through lateral advection is more important in some areas. While at the bottom, the infauna processes the food in many different ways, and the feeding modes can be categorised into more than 20 functional groups, but fewer are present in brackish water. This categorisation is based on animal mobility and where and how they ingest the food. Animal activity in the sediment, bioturbation, has a significant effect on redox conditions and diagenetic processes. Structures in the sediment due to infaunal presence and activity can be observed in situ by sediment profile imaging, and the biogenic structures and redox conditions can be parameterised and have been shown to correlate to benthic community successional stages. The largest threat to benthic faunal biodiversity is the spread of near-bottom oxygen deficiency in many enclosed are stratified coastal areas.

  15. EXPLORING THE LOW-MASS END OF THE MBH-σ* RELATION WITH ACTIVE GALAXIES

    International Nuclear Information System (INIS)

    Xiao Ting; Barth, Aaron J.; Greene, Jenny E.; Ludwig, Randi R.; Ho, Luis C.; Bentz, Misty C.; Jiang Yanfei

    2011-01-01

    We present new measurements of stellar velocity dispersions, using spectra obtained with the Keck Echellette Spectrograph and Imager (ESI) and the Magellan Echellette (MagE), for 76 Seyfert 1 galaxies from the recent catalog of Greene and Ho. These objects were selected from the Sloan Digital Sky Survey (SDSS) to have estimated black hole (BH) masses below 2 x 10 6 M sun . Combining our results with previous ESI observations of similar objects, we obtain an expanded sample of 93 galaxies and examine the relation between BH mass and velocity dispersion (the M BH -σ * relation) for active galaxies with low BH masses. The low-mass active galaxies tend to follow the extrapolation of the M BH -σ * relation of inactive galaxies. Including results for active galaxies of higher BH mass from the literature, we find a zero point α = 7.68 ± 0.08 and slope of β = 3.32 ± 0.22 for the M BH -σ * relation (in the form log M BH = α + βlog (σ * /200 km s -1 )), with intrinsic scatter of 0.46 ± 0.03 dex. This result is consistent, within the uncertainties, with the slope of the M BH -σ * relation for reverberation-mapped active galaxies with BH masses from 10 6 to 10 9 M sun . For the subset of our sample having morphological information from Hubble Space Telescope images, we examine the slope of the M BH -σ * relation separately for subsamples of barred and unbarred host galaxies, and find no significant evidence for a difference in slope. We do find a mild offset between low-inclination and high-inclination disk galaxies, such that more highly inclined galaxies tend to have larger σ * at a given value of BH mass, presumably due to the contribution of disk rotation within the spectroscopic aperture. We also find that the velocity dispersion of the ionized gas, measured from narrow emission lines including [N II] λ6583, [S II] λλ6716, 6731, and the core of [O III] λ5007 (with the blueshifted wing removed), trace the stellar velocity dispersion well for this large

  16. The role of crisis in family crisis intervention: do crisis experience and crisis change matter?

    NARCIS (Netherlands)

    Al, C.M.W.; Stams, G.J.J.M.; van der Laan, P.H.; Asscher, J.J.

    2011-01-01

    Evaluation studies of crisis intervention have focused on prevention of out-of-home placement of children or family functioning, but largely neglected the aspect of crisis. The present study examined crisis in 183 families receiving Family Crisis Intervention (FCI), addressing crisis characteristics

  17. Leaching of rapidly quenched Al65Cu20Fe15 quasicrystalline ribbons

    Indian Academy of Sciences (India)

    2017-12-06

    Dec 6, 2017 ... stood that Al–Cu–Fe QC also presents an FCI structure similar to that .... that the precipitation rate of Fe is lower than that of Cu. Figure 2a shows the .... Renewable Energy (MNRE), India, under Mission Mode. Hydrogen ...

  18. Genesis of a UK Faculty of Clinical Informatics at a time of anticipation for some, and ruby, golden and diamond celebrations for others

    Directory of Open Access Journals (Sweden)

    Simon de Lusignan

    2018-01-01

    Full Text Available This Editorial marks the launch of the UK Faculty of Clinical Informatics (FCI at the time when non-clinically qualified informaticians are anticipating the lauch of  the Federation of Informatics Professionals in Health and Care (Fed-IP.

  19. Administrative Costs Associated With Physician Billing and Insurance-Related Activities at an Academic Health Care System.

    Science.gov (United States)

    Tseng, Phillip; Kaplan, Robert S; Richman, Barak D; Shah, Mahek A; Schulman, Kevin A

    2018-02-20

    Administrative costs in the US health care system are an important component of total health care spending, and a substantial proportion of these costs are attributable to billing and insurance-related activities. To examine and estimate the administrative costs associated with physician billing activities in a large academic health care system with a certified electronic health record system. This study used time-driven activity-based costing. Interviews were conducted with 27 health system administrators and 34 physicians in 2016 and 2017 to construct a process map charting the path of an insurance claim through the revenue cycle management process. These data were used to calculate the cost for each major billing and insurance-related activity and were aggregated to estimate the health system's total cost of processing an insurance claim. Estimated time required to perform billing and insurance-related activities, based on interviews with management personnel and physicians. Estimated billing and insurance-related costs for 5 types of patient encounters: primary care visits, discharged emergency department visits, general medicine inpatient stays, ambulatory surgical procedures, and inpatient surgical procedures. Estimated processing time and total costs for billing and insurance-related activities were 13 minutes and $20.49 for a primary care visit, 32 minutes and $61.54 for a discharged emergency department visit, 73 minutes and $124.26 for a general inpatient stay, 75 minutes and $170.40 for an ambulatory surgical procedure, and 100 minutes and $215.10 for an inpatient surgical procedure. Of these totals, time and costs for activities carried out by physicians were estimated at a median of 3 minutes or $6.36 for a primary care visit, 3 minutes or $10.97 for an emergency department visit, 5 minutes or $13.29 for a general inpatient stay, 15 minutes or $51.20 for an ambulatory surgical procedure, and 15 minutes or $51.20 for an inpatient surgical procedure. Of

  20. CEA and mining industry

    International Nuclear Information System (INIS)

    Anon.

    2003-01-01

    The French atomic energy commission (CEA) is involved in the mining industry in several ways: - in the front-end of the nuclear industry through its daughter companies and participations in the exploration and exploitation of uranium ores, but also of gold and alloy metals with a 26% participation in Eramet company, the world leader of manganese and nickel. This activity is the main occupation of Cogema daughter company, via the Areva holding; - in the back-end of the nuclear fuel cycle with the delicate problem of the management of radioactive wastes; - in parallel with the nuclear industry through an important activity in semiconductor materials (FCI and SMTElectronics); - and finally through various research works on several mineral compounds. This article focusses on the fuel cycle aspects of the CEA activities and concludes with the research works carried out today on thermonuclear fusion. (J.S.)

  1. Fuel fragmentation model advances using TEXAS-V

    Energy Technology Data Exchange (ETDEWEB)

    Corradini, M.L.; El-Beshbeeshy, M.; Nilsuwankowsit, S.; Tang, J. [Wisconsin Univ., Madison, WI (United States). Dept. of Nuclear Engineering and Engineering Physics

    1998-01-01

    Because an energetic fuel-coolant interaction may be a safety hazard, experiments are being conducted to investigate the fuel-coolant mixing/quenching process (FARO) as well as the energetics of vapor explosion propagation for high temperature fuel melt simulants (KROTOS, WFCI, ZrEX). In both types of experiments, the dynamic breakup of the fuel is one of the key aspects that must be fundamentally understood to better estimate the magnitude of the mixing/quenching process or the explosion energetics. To aid our understanding the TEXAS fuel-coolant interaction computer model has been developed and is being used to analyze these experiments. Recently, the models for dynamic fuel fragmentation during the mixing and explosion phases of the FCI have been improved by further insights into these processes. The purpose of this paper is to describe these enhancements and to demonstrate their improvements by analysis of particular JRC FCI data. (author)

  2. Accelerating Full Configuration Interaction Calculations for Nuclear Structure

    International Nuclear Information System (INIS)

    Yang, Chao; Sternberg, Philip; Maris, Pieter; Ng, Esmond; Sosonkina, Masha; Le, Hung Viet; Vary, James; Yang, Chao

    2008-01-01

    One of the emerging computational approaches in nuclear physics is the full configuration interaction (FCI) method for solving the many-body nuclear Hamiltonian in a sufficiently large single-particle basis space to obtain exact answers - either directly or by extrapolation. The lowest eigenvalues and corresponding eigenvectors for very large, sparse and unstructured nuclear Hamiltonian matrices are obtained and used to evaluate additional experimental quantities. These matrices pose a significant challenge to the design and implementation of efficient and scalable algorithms for obtaining solutions on massively parallel computer systems. In this paper, we describe the computational strategies employed in a state-of-the-art FCI code MFDn (Many Fermion Dynamics - nuclear) as well as techniques we recently developed to enhance the computational efficiency of MFDn. We will demonstrate the current capability of MFDn and report the latest performance improvement we have achieved. We will also outline our future research directions

  3. Improved Volitional Recall of Motor-Imagery-Related Brain Activation Patterns Using Real-Time Functional MRI-Based Neurofeedback.

    Science.gov (United States)

    Bagarinao, Epifanio; Yoshida, Akihiro; Ueno, Mika; Terabe, Kazunori; Kato, Shohei; Isoda, Haruo; Nakai, Toshiharu

    2018-01-01

    Motor imagery (MI), a covert cognitive process where an action is mentally simulated but not actually performed, could be used as an effective neurorehabilitation tool for motor function improvement or recovery. Recent approaches employing brain-computer/brain-machine interfaces to provide online feedback of the MI during rehabilitation training have promising rehabilitation outcomes. In this study, we examined whether participants could volitionally recall MI-related brain activation patterns when guided using neurofeedback (NF) during training. The participants' performance was compared to that without NF. We hypothesized that participants would be able to consistently generate the relevant activation pattern associated with the MI task during training with NF compared to that without NF. To assess activation consistency, we used the performance of classifiers trained to discriminate MI-related brain activation patterns. Our results showed significantly higher predictive values of MI-related activation patterns during training with NF. Additionally, this improvement in the classification performance tends to be associated with the activation of middle temporal gyrus/inferior occipital gyrus, a region associated with visual motion processing, suggesting the importance of performance monitoring during MI task training. Taken together, these findings suggest that the efficacy of MI training, in terms of generating consistent brain activation patterns relevant to the task, can be enhanced by using NF as a mechanism to enable participants to volitionally recall task-related brain activation patterns.

  4. Improved Volitional Recall of Motor-Imagery-Related Brain Activation Patterns Using Real-Time Functional MRI-Based Neurofeedback

    Directory of Open Access Journals (Sweden)

    Epifanio Bagarinao

    2018-04-01

    Full Text Available Motor imagery (MI, a covert cognitive process where an action is mentally simulated but not actually performed, could be used as an effective neurorehabilitation tool for motor function improvement or recovery. Recent approaches employing brain–computer/brain–machine interfaces to provide online feedback of the MI during rehabilitation training have promising rehabilitation outcomes. In this study, we examined whether participants could volitionally recall MI-related brain activation patterns when guided using neurofeedback (NF during training. The participants’ performance was compared to that without NF. We hypothesized that participants would be able to consistently generate the relevant activation pattern associated with the MI task during training with NF compared to that without NF. To assess activation consistency, we used the performance of classifiers trained to discriminate MI-related brain activation patterns. Our results showed significantly higher predictive values of MI-related activation patterns during training with NF. Additionally, this improvement in the classification performance tends to be associated with the activation of middle temporal gyrus/inferior occipital gyrus, a region associated with visual motion processing, suggesting the importance of performance monitoring during MI task training. Taken together, these findings suggest that the efficacy of MI training, in terms of generating consistent brain activation patterns relevant to the task, can be enhanced by using NF as a mechanism to enable participants to volitionally recall task-related brain activation patterns.

  5. Objectively measured walkability and active transport and weight-related outcomes in adults: a systematic review.

    Science.gov (United States)

    Grasser, Gerlinde; Van Dyck, Delfien; Titze, Sylvia; Stronegger, Willibald

    2013-08-01

    The aim of this study was to investigate which GIS-based measures of walkability (density, land-use mix, connectivity and walkability indexes) in urban and suburban neighbourhoods are used in research and which of them are consistently associated with walking and cycling for transport, overall active transportation and weight-related measures in adults. A systematic review of English publications using PubMed, Science Direct, Active Living Research Literature Database, the Transportation Research Information Service and reference lists was conducted. The search terms utilised were synonyms for GIS in combination with synonyms for the outcomes. Thirty-four publications based on 19 different studies were eligible. Walkability measures such as gross population density, intersection density and walkability indexes most consistently correlated with measures of physical activity for transport. Results on weight-related measures were inconsistent. More research is needed to determine whether walkability is an appropriate measure for predicting weight-related measures and overall active transportation. As most of the consistent correlates, gross population density, intersection density and the walkability indexes have the potential to be used in planning and monitoring.

  6. IAEA Activities in the Area of Fast Reactors and Related Fuels and Fuel Cycles

    International Nuclear Information System (INIS)

    Monti, S.; Basak, U.; Dyck, G.; Inozemtsev, V.; Toti, A.; Zeman, A.

    2013-01-01

    Summary: • The IAEA role to support fast reactors and associated fuel cycle development programmes; • Main IAEA activities on fast reactors and related fuel and fuel cycle technology; • Main IAEA deliverables on fast reactors and related fuel and fuel cycle technology

  7. Brain activity and cognitive transition during childhood: A longitudinal event-related brain potential study.

    NARCIS (Netherlands)

    Stauder, J.E.A.; Molenaar, P.C.M.; van der Molen, M.W.

    1998-01-01

    Examined the relation between brain activation and cognitive development using event-related brain potentials (ERPs) and a longitudinal design. 5 yr old females performed a visual recognition ('oddball') task and an experimental analogue of the Piagetian conservation of liquid quantity task At three

  8. EDA activities related to safety

    International Nuclear Information System (INIS)

    Gordon, C.; Raeder, J.

    2001-01-01

    This article reviews the accomplishments in ITER safety analysis during the course of the Engineering Design Activities (EDA). The key aspects of ITER safety analysis are: effluents and emissions from normal operation, including planned maintenance activities; occupational safety for workers at the facility; radioactive materials and wastes generated during operation and from decommissioning ; potential incidents and accidents and the resulting transients. As a result of the work during the EDA it is concluded that ITER is safe

  9. Cerebral Activations Related to Writing and Drawing with Each Hand

    Science.gov (United States)

    Potgieser, Adriaan R. E.; van der Hoorn, Anouk; de Jong, Bauke M.

    2015-01-01

    Background Writing is a sequential motor action based on sensorimotor integration in visuospatial and linguistic functional domains. To test the hypothesis of lateralized circuitry concerning spatial and language components involved in such action, we employed an fMRI paradigm including writing and drawing with each hand. In this way, writing-related contributions of dorsal and ventral premotor regions in each hemisphere were assessed, together with effects in wider distributed circuitry. Given a right-hemisphere dominance for spatial action, right dorsal premotor cortex dominance was expected in left-hand writing while dominance of the left ventral premotor cortex was expected during right-hand writing. Methods Sixteen healthy right-handed subjects were scanned during audition-guided writing of short sentences and simple figure drawing without visual feedback. Tapping with a pencil served as a basic control task for the two higher-order motor conditions. Activation differences were assessed with Statistical Parametric Mapping (SPM). Results Writing and drawing showed parietal-premotor and posterior inferior temporal activations in both hemispheres when compared to tapping. Drawing activations were rather symmetrical for each hand. Activations in left- and right-hand writing were left-hemisphere dominant, while right dorsal premotor activation only occurred in left-hand writing, supporting a spatial motor contribution of particularly the right hemisphere. Writing contrasted to drawing revealed left-sided activations in the dorsal and ventral premotor cortex, Broca’s area, pre-Supplementary Motor Area and posterior middle and inferior temporal gyri, without parietal activation. Discussion The audition-driven postero-inferior temporal activations indicated retrieval of virtual visual form characteristics in writing and drawing, with additional activation concerning word form in the left hemisphere. Similar parietal processing in writing and drawing pointed at a

  10. Cerebral activations related to writing and drawing with each hand.

    Science.gov (United States)

    Potgieser, Adriaan R E; van der Hoorn, Anouk; de Jong, Bauke M

    2015-01-01

    Writing is a sequential motor action based on sensorimotor integration in visuospatial and linguistic functional domains. To test the hypothesis of lateralized circuitry concerning spatial and language components involved in such action, we employed an fMRI paradigm including writing and drawing with each hand. In this way, writing-related contributions of dorsal and ventral premotor regions in each hemisphere were assessed, together with effects in wider distributed circuitry. Given a right-hemisphere dominance for spatial action, right dorsal premotor cortex dominance was expected in left-hand writing while dominance of the left ventral premotor cortex was expected during right-hand writing. Sixteen healthy right-handed subjects were scanned during audition-guided writing of short sentences and simple figure drawing without visual feedback. Tapping with a pencil served as a basic control task for the two higher-order motor conditions. Activation differences were assessed with Statistical Parametric Mapping (SPM). Writing and drawing showed parietal-premotor and posterior inferior temporal activations in both hemispheres when compared to tapping. Drawing activations were rather symmetrical for each hand. Activations in left- and right-hand writing were left-hemisphere dominant, while right dorsal premotor activation only occurred in left-hand writing, supporting a spatial motor contribution of particularly the right hemisphere. Writing contrasted to drawing revealed left-sided activations in the dorsal and ventral premotor cortex, Broca's area, pre-Supplementary Motor Area and posterior middle and inferior temporal gyri, without parietal activation. The audition-driven postero-inferior temporal activations indicated retrieval of virtual visual form characteristics in writing and drawing, with additional activation concerning word form in the left hemisphere. Similar parietal processing in writing and drawing pointed at a common mechanism by which such visually

  11. Legal framework related to access to information and public participation on nuclear activity

    International Nuclear Information System (INIS)

    Arias, M. C.; Bernaldez, A.L.; Ghiggeri, M.; Tula, C.

    2011-01-01

    The right of access to information by citizens about activities related to scientific and technological development of nuclear energy for peaceful uses, has evolved over time. Governments began to perceive the necessity and the benefits of informing the community, who manifested certain prejudices about nuclear activity as a consequence of the propelling of nuclear bombs in Nagasaki and Hiroshima. With the advent of environmental law and the influence of its principles, the idea of transparency of information in the nuclear field was imposed, and also the importance of both the inhabitants of countries with nuclear developments and neighbouring countries who may be affected by the bordering effects of ionizing radiation, could have access to information and to participate actively. The access to information and citizen participation has been institutionalized and reflected in international regulations through international conventions subscribed by our country and nationally through the National Constitution, the Provincials Constitutions, the City of Buenos Aires Constitution, Laws No. 25.675, 25.831 and PEN Decree No. 1172/03, among others. The present work aims to make an overview of the legal framework related to access to information on nuclear activity. (authors) [es

  12. Using activity-related behavioural features towards more effective automatic stress detection.

    Directory of Open Access Journals (Sweden)

    Dimitris Giakoumis

    Full Text Available This paper introduces activity-related behavioural features that can be automatically extracted from a computer system, with the aim to increase the effectiveness of automatic stress detection. The proposed features are based on processing of appropriate video and accelerometer recordings taken from the monitored subjects. For the purposes of the present study, an experiment was conducted that utilized a stress-induction protocol based on the stroop colour word test. Video, accelerometer and biosignal (Electrocardiogram and Galvanic Skin Response recordings were collected from nineteen participants. Then, an explorative study was conducted by following a methodology mainly based on spatiotemporal descriptors (Motion History Images that are extracted from video sequences. A large set of activity-related behavioural features, potentially useful for automatic stress detection, were proposed and examined. Experimental evaluation showed that several of these behavioural features significantly correlate to self-reported stress. Moreover, it was found that the use of the proposed features can significantly enhance the performance of typical automatic stress detection systems, commonly based on biosignal processing.

  13. Quantum Chemistry via Walks in Determinant Space

    Energy Technology Data Exchange (ETDEWEB)

    Umrigar, Cyrus J. [Cornell Univ., Ithaca, NY (United States)

    2016-01-05

    There are many chemical questions of practical interest to the DOE that could be answered if there were an electronic structure method that provided consistently accurate results for all systems at an affordable computational cost. The coupled cluster method with single, double and perturbative triple excitations (CCSD(T)) is the most frequently used high-order method, but it has known deficiencies, e.g., in the description of stretched bonds. The full configuration interaction (FCI) method is the most robust method for treating electronic correlations, but it is little used because its computational cost scales exponentially in the size of the system. The largest calculation that has been done to date employed 10 billion determinants. In this regard, there was a major advance in 2010. The Alavi group at Cambridge University developed a stochastic approach to FCI --- combining it with ideas from quantum Monte Carlo (QMC) --- called FCIQMC, that allows one to go to a far larger number of determinants in certain circumstances. The computational cost is exponential in the system and basis size but with a much reduced exponent compared to conventional FCI. In this project Umrigar's group made several major improvements to the FCIQMC method that increased its efficiency by many orders of magnitude. In addition this project resulted in a cross-fertilization of ideas between the FCIQMC method, the older phaseless auxilliary-field quantum Monte Carlo (AFQMC) method developed by Zhang and Krakauer (two of the PI's of this project), and symmetry-restored wavefunctions developed by Scuseria (also a PI of this project).

  14. Analysis of the KROTOS KFC test by coupling X-Ray image analysis and MC3D calculations

    Energy Technology Data Exchange (ETDEWEB)

    Brayer, C.; Charton, A.; Grishchenko, D.; Fouquart, P.; Bullado, Y.; Compagnon, F.; Correggio, P.; Cassiaut-Louis, N.; Piluso, P. [Commissariat a l' Energie Atomique et Aux Energies Alternatives, CEA Cadarache, DEN, F-13108 Saint-Paul-Les-Durance (France)

    2012-07-01

    During a hypothetical severe accident sequence in a Pressurized Water Reactor (PWR), the hot molten materials (corium) issuing from the degraded reactor core may generate a steam explosion if they come in contact with water and may damage the structures and threaten the reactor integrity. The SERENA program is an international OECD project that aims at helping the understanding of this phenomenon also called Fuel Coolant Interaction (FCI) by providing data. CEA takes part in this program by performing tests in its KROTOS facility where steam explosions using prototypic corium can be triggered. Data about the different phases in the premixing are extracted from the KROTOS X-Ray radioscopy images by using KIWI software (KROTOS Image analysis of Water-corium Interaction) currently developed by CEA. The MC3D code, developed by IRSN, is a thermal-hydraulic multiphase code mainly dedicated to FCI studies. It is composed of two applications: premixing and explosion. An overall FCI calculation with MC3D requires a premixing calculation followed by an explosion calculation. The present paper proposes an alternative approach in which all the features of the premixing are extracted from the X-Ray pictures using the KIWI software and transferred to an MC3D dataset for a direct simulation of the explosion. The main hypothesis are discussed as well as the first explosion results obtained with MC3D for the KROTOS KFC test. These results are rather encouraging and are analyzed on the basis of comparisons with the experimental data. (authors)

  15. Interpreting force concept inventory scores: Normalized gain and SAT scores

    Directory of Open Access Journals (Sweden)

    Jeffrey J. Steinert

    2007-05-01

    Full Text Available Preinstruction SAT scores and normalized gains (G on the force concept inventory (FCI were examined for individual students in interactive engagement (IE courses in introductory mechanics at one high school (N=335 and one university (N=292 , and strong, positive correlations were found for both populations ( r=0.57 and r=0.46 , respectively. These correlations are likely due to the importance of cognitive skills and abstract reasoning in learning physics. The larger correlation coefficient for the high school population may be a result of the much shorter time interval between taking the SAT and studying mechanics, because the SAT may provide a more current measure of abilities when high school students begin the study of mechanics than it does for college students, who begin mechanics years after the test is taken. In prior research a strong correlation between FCI G and scores on Lawson’s Classroom Test of Scientific Reasoning for students from the same two schools was observed. Our results suggest that, when interpreting class average normalized FCI gains and comparing different classes, it is important to take into account the variation of students’ cognitive skills, as measured either by the SAT or by Lawson’s test. While Lawson’s test is not commonly given to students in most introductory mechanics courses, SAT scores provide a readily available alternative means of taking account of students’ reasoning abilities. Knowing the students’ cognitive level before instruction also allows one to alter instruction or to use an intervention designed to improve students’ cognitive level.

  16. Interpreting force concept inventory scores: Normalized gain and SAT scores

    Directory of Open Access Journals (Sweden)

    Vincent P. Coletta

    2007-05-01

    Full Text Available Preinstruction SAT scores and normalized gains (G on the force concept inventory (FCI were examined for individual students in interactive engagement (IE courses in introductory mechanics at one high school (N=335 and one university (N=292, and strong, positive correlations were found for both populations (r=0.57 and r=0.46, respectively. These correlations are likely due to the importance of cognitive skills and abstract reasoning in learning physics. The larger correlation coefficient for the high school population may be a result of the much shorter time interval between taking the SAT and studying mechanics, because the SAT may provide a more current measure of abilities when high school students begin the study of mechanics than it does for college students, who begin mechanics years after the test is taken. In prior research a strong correlation between FCI G and scores on Lawson’s Classroom Test of Scientific Reasoning for students from the same two schools was observed. Our results suggest that, when interpreting class average normalized FCI gains and comparing different classes, it is important to take into account the variation of students’ cognitive skills, as measured either by the SAT or by Lawson’s test. While Lawson’s test is not commonly given to students in most introductory mechanics courses, SAT scores provide a readily available alternative means of taking account of students’ reasoning abilities. Knowing the students’ cognitive level before instruction also allows one to alter instruction or to use an intervention designed to improve students’ cognitive level.

  17. Students' proficiency scores within multitrait item response theory

    Science.gov (United States)

    Scott, Terry F.; Schumayer, Daniel

    2015-12-01

    In this paper we present a series of item response models of data collected using the Force Concept Inventory. The Force Concept Inventory (FCI) was designed to poll the Newtonian conception of force viewed as a multidimensional concept, that is, as a complex of distinguishable conceptual dimensions. Several previous studies have developed single-trait item response models of FCI data; however, we feel that multidimensional models are also appropriate given the explicitly multidimensional design of the inventory. The models employed in the research reported here vary in both the number of fitting parameters and the number of underlying latent traits assumed. We calculate several model information statistics to ensure adequate model fit and to determine which of the models provides the optimal balance of information and parsimony. Our analysis indicates that all item response models tested, from the single-trait Rasch model through to a model with ten latent traits, satisfy the standard requirements of fit. However, analysis of model information criteria indicates that the five-trait model is optimal. We note that an earlier factor analysis of the same FCI data also led to a five-factor model. Furthermore the factors in our previous study and the traits identified in the current work match each other well. The optimal five-trait model assigns proficiency scores to all respondents for each of the five traits. We construct a correlation matrix between the proficiencies in each of these traits. This correlation matrix shows strong correlations between some proficiencies, and strong anticorrelations between others. We present an interpretation of this correlation matrix.

  18. Assessing students’ conceptual knowledge of electricity and magnetism

    Directory of Open Access Journals (Sweden)

    Michele W. McColgan

    2017-10-01

    Full Text Available We present the Electricity and Magnetism Conceptual Assessment (EMCA, a new assessment aligned with second-semester introductory physics courses. Topics covered include electrostatics, electric fields, circuits, magnetism, and induction. We have two motives for writing a new assessment. First, we find other assessments such as the Brief Electricity and Magnetism Assessment and the Conceptual Survey on Electricity and Magnetism not well aligned with the topics and content depth of our courses. We want to test introductory physics content at a level appropriate for our students. Second, we want the assessment to yield scores and gains comparable to the widely used Force Concept Inventory (FCI. After five testing and revision cycles, the assessment was finalized in early 2015 and is available online. We present performance results for a cohort of 225 students at Siena College who were enrolled in our algebra- and calculus-based physics courses during the spring 2015 and 2016 semesters. We provide pretest, post-test, and gain analyses, as well as individual question and whole test statistics to quantify difficulty and reliability. In addition, we compare EMCA and FCI scores and gains, and we find that students’ FCI scores are strongly correlated with their performance on the EMCA. Finally, the assessment was piloted in an algebra-based physics course at George Washington University (GWU. We present performance results for a cohort of 130 GWU students and we find that their EMCA scores are comparable to the scores of students in our calculus-based physics course.

  19. Fuel coolant interaction experiment by direct electrical heating method

    International Nuclear Information System (INIS)

    Takeda, Tsuneo; Hirano, Kenmei

    1979-01-01

    In the PCM (Power Cooling Mismatch) experiments, the FCI (Fuel Coolant Interaction) test is one of necessary tests in order to predict various phenomena that occur during PCM in the core. A direct electrical heating method is used for the FCI tests for fuel pellet temperature of over 1000 0 C. Therefore, preheating is required before initiating the direct electrical heating. The fuel pin used in the FCI tests is typical LWR fuel element, which is surrounded by coolant water. It is undersirable to heat up the coolant water during preheating of the fuel pin. Therefore, a zirconia (ZrO 2 ) pellet which is similar to a UO 2 pellet in physical and chemical properties is used. Electric property (electric conductivity) of ZrO 2 is particularly suitable for direct electrical heating as in the case of UO 2 . In this experiment, ZrO 2 pellet (melting point 2500 0 C) melting was achieved by use of both preheating and direct electrical heating. Temperature changes of coolant and fuel surface, as well as the pressure change of coolant water, were measured. The molten fuel interacted with the coolant and generated shock waves. A portion of this molten fuel fragmented into small particles during this interaction. The peak pressure of the observed shock wave was about 35 bars. The damaged fuel pin was photographed after disassembly. This report shows the measured coolant pressure changes and the coolant temperature changes, as well as photographs of damaged fuel pin and fuel fragments. (author)

  20. Effect of Modeling Instruction on Concept Knowledge Among Ninth Grade Physics Students

    Science.gov (United States)

    Ditmore, Devin Alan

    A basic knowledge of physics concepts is the gateway to success through high-paying careers in science, technology, engineering, and mathematics (STEM). Many students show little understanding of concepts following traditional physics instruction. As an alternative to current lecture-based approaches for high school physics instruction, Piaget's theory of cognitive development supports using real scientific experiences to lead learners from concrete to formal understanding of complex concepts. Modeling instruction (MI) is a pedagogy that guides learners through genuine scientific experiences. This project study analyzed the effects of MI on 9th grade physics students' gains on the test measuring mastery of physics concepts, Force Concept Inventory (FCI). A quasi-experimental design was used to compare the FCI scores of a traditional lecture-taught control group to a treatment group taught using MI. A t test t(-.201) = 180.26, p = .841 comparing the groups and an analysis of variance F(2,181) = 5.20 comparing female to male students indicated MI had no significant positive effect on students. A partial eta squared of the effect size showed that 5.4% of the variance in FCI gains was accounted for by gender, favoring female participants for both groups. The significant relationship between content and gender bears further inquiry. A lesson plan guide was designed to help teachers use computer simulation technology within the MI curriculum. The project promotes positive social change by exploring further ways to help adolescents experience success in physics at the beginning of high school, leading to future success in all STEM areas.

  1. Analysis of the KROTOS KFC test by coupling X-Ray image analysis and MC3D calculations

    International Nuclear Information System (INIS)

    Brayer, C.; Charton, A.; Grishchenko, D.; Fouquart, P.; Bullado, Y.; Compagnon, F.; Correggio, P.; Cassiaut-Louis, N.; Piluso, P.

    2012-01-01

    During a hypothetical severe accident sequence in a Pressurized Water Reactor (PWR), the hot molten materials (corium) issuing from the degraded reactor core may generate a steam explosion if they come in contact with water and may damage the structures and threaten the reactor integrity. The SERENA program is an international OECD project that aims at helping the understanding of this phenomenon also called Fuel Coolant Interaction (FCI) by providing data. CEA takes part in this program by performing tests in its KROTOS facility where steam explosions using prototypic corium can be triggered. Data about the different phases in the premixing are extracted from the KROTOS X-Ray radioscopy images by using KIWI software (KROTOS Image analysis of Water-corium Interaction) currently developed by CEA. The MC3D code, developed by IRSN, is a thermal-hydraulic multiphase code mainly dedicated to FCI studies. It is composed of two applications: premixing and explosion. An overall FCI calculation with MC3D requires a premixing calculation followed by an explosion calculation. The present paper proposes an alternative approach in which all the features of the premixing are extracted from the X-Ray pictures using the KIWI software and transferred to an MC3D dataset for a direct simulation of the explosion. The main hypothesis are discussed as well as the first explosion results obtained with MC3D for the KROTOS KFC test. These results are rather encouraging and are analyzed on the basis of comparisons with the experimental data. (authors)

  2. Amygdala activity related to enhanced memory for pleasant and aversive stimuli.

    Science.gov (United States)

    Hamann, S B; Ely, T D; Grafton, S T; Kilts, C D

    1999-03-01

    Pleasant or aversive events are better remembered than neutral events. Emotional enhancement of episodic memory has been linked to the amygdala in animal and neuropsychological studies. Using positron emission tomography, we show that bilateral amygdala activity during memory encoding is correlated with enhanced episodic recognition memory for both pleasant and aversive visual stimuli relative to neutral stimuli, and that this relationship is specific to emotional stimuli. Furthermore, data suggest that the amygdala enhances episodic memory in part through modulation of hippocampal activity. The human amygdala seems to modulate the strength of conscious memory for events according to emotional importance, regardless of whether the emotion is pleasant or aversive.

  3. World uranium exploration, resources, production and related activities

    International Nuclear Information System (INIS)

    Hanly, A.

    2014-01-01

    A Nuclear Energy Series publication entitled “World Uranium Exploration, Resources, Production and Related Activities” (WUERPRA) will soon be published by the IAEA. The objective of the publication is to provide a comprehensive compilation of historic uranium exploration, resources, production and related activities based primarily on information from the 1966 to 2009 editions of the publication “Uranium Resources, Production and Demand”, a joint publication of the International Atomic Energy Agency and the Nuclear Energy Agency/Organization for Economic Cooperation and Development commonly known as the ‘Red Book’. This has been supplemented by historic information from other reliable sources. The publications also include, where enough information was available, descriptions of the relative potential for discovery of new uranium resources on a per country basis. To recover complete historic information it is frequently necessary to refer to earlier editions of the Red Book, many of which may not be readily available. This publication aims to provide one comprehensive source for much of this type of information which will reduce the effort required to prepare future editions of the Red Book, as well as make the historic Red Book information, together with select related information from other sources, more readily available to all users with an interest in uranium. WUERPRA comprises 6 volumes containing 164 country reports, each organized by region; Volume 1: Africa (53 countries); Volume 2: Central, Eastern and Southeastern Europe (25 countries); Volume 3: Southeastern Asia, Pacific, East Asia (18 countries); Volume 4: Western Europe (22 countries); Volume 5: Middle East, Central and Southern Asia (19 countries), and; Volume 6: North America, Central America and South America (27 countries). The report also contains information on countries that have not reported to the Red Book. The poster will summarize select major highlights from each volume

  4. Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds.

    Science.gov (United States)

    Horenstein, Nicole A; Quadri, Marta; Stokes, Clare; Shoaib, Mohammed; Papke, Roger L

    2017-10-03

    The use of betel quid is the most understudied major addiction in the world. The neuropsychological activity of betel quid has been attributed to alkaloids of Areca catechu. With the goal of developing novel addiction treatments, we evaluate the muscarinic and nicotinic activity of the four major Areca alkaloids: arecoline, arecaidine, guvacoline, and guvacine and four structurally related compounds. Acetylcholine receptors were expressed in Xenopus oocytes and studied with two-electrode voltage clamp. Both arecoline- and guvacoline-activated muscarinic acetylcholine receptors (mAChR), while only arecoline produced significant activation of nicotinic AChR (nAChR). We characterized four additional arecoline-related compounds, seeking an analog that would retain selective activity for a α4* nAChR, with diminished effects on mAChR and not be a desensitizer of α7 nAChR. We show that this profile is largely met by isoarecolone. Three additional arecoline analogs were characterized. While the quaternary dimethyl analog had a broad range of activities, including activation of mAChR and muscle-type nAChR, the methyl analog only activated a range of α4* nAChR, albeit with low potency. The ethyl analog had no detectable cholinergic activity. Evidence indicates that α4* nAChR are at the root of nicotine addiction, and this may also be the case for betel addiction. Our characterization of isoarecolone and 1-(4-methylpiperazin-1-yl) ethanone as truly selective α4*nAChR selective partial agonists with low muscarinic activity may point toward a promising new direction for the development of drugs to treat both nicotine and betel addiction. Nearly 600 million people use Areca nut, often with tobacco. Two of the Areca alkaloids are muscarinic acetylcholine receptor agonists, and one, arecoline, is a partial agonist for the α4* nicotinic acetylcholine receptors (nAChR) associated with tobacco addiction. The profile of arecoline activity suggested its potential to be used as a

  5. Impact of Arts-Related Activities on the Perceived Quality of Life

    Science.gov (United States)

    Michalos, Alex C.; Kahlke, P. Maurine

    2008-01-01

    The aim of this investigation was to measure the impact of arts-related activities on the perceived or experienced quality of life. In the fall of 2006 a questionnaire was mailed out to a random selection of 2000 households in each of five British Columbia communities, and 1027 were returned completed. The total and individual community samples…

  6. Parkinson-related changes of activation in visuomotor brain regions during perceived forward self-motion.

    Directory of Open Access Journals (Sweden)

    Anouk van der Hoorn

    Full Text Available Radial expanding optic flow is a visual consequence of forward locomotion. Presented on screen, it generates illusionary forward self-motion, pointing at a close vision-gait interrelation. As particularly parkinsonian gait is vulnerable to external stimuli, effects of optic flow on motor-related cerebral circuitry were explored with functional magnetic resonance imaging in healthy controls (HC and patients with Parkinson's disease (PD. Fifteen HC and 22 PD patients, of which 7 experienced freezing of gait (FOG, watched wide-field flow, interruptions by narrowing or deceleration and equivalent control conditions with static dots. Statistical parametric mapping revealed that wide-field flow interruption evoked activation of the (pre-supplementary motor area (SMA in HC, which was decreased in PD. During wide-field flow, dorsal occipito-parietal activations were reduced in PD relative to HC, with stronger functional connectivity between right visual motion area V5, pre-SMA and cerebellum (in PD without FOG. Non-specific 'changes' in stimulus patterns activated dorsolateral fronto-parietal regions and the fusiform gyrus. This attention-associated network was stronger activated in HC than in PD. PD patients thus appeared compromised in recruiting medial frontal regions facilitating internally generated virtual locomotion when visual motion support falls away. Reduced dorsal visual and parietal activations during wide-field optic flow in PD were explained by impaired feedforward visual and visuomotor processing within a magnocellular (visual motion functional chain. Compensation of impaired feedforward processing by distant fronto-cerebellar circuitry in PD is consistent with motor responses to visual motion stimuli being either too strong or too weak. The 'change'-related activations pointed at covert (stimulus-driven attention.

  7. Weather is not significantly correlated with destination-specific transport-related physical activity among adults: A large-scale temporally matched analysis.

    Science.gov (United States)

    Durand, Casey P; Zhang, Kai; Salvo, Deborah

    2017-08-01

    Weather is an element of the natural environment that could have a significant effect on physical activity. Existing research, however, indicates only modest correlations between measures of weather and physical activity. This prior work has been limited by a failure to use time-matched weather and physical activity data, or has not adequately examined the different domains of physical activity (transport, leisure, occupational, etc.). Our objective was to identify the correlation between weather variables and destination-specific transport-related physical activity in adults. Data were sourced from the California Household Travel Survey, collected in 2012-3. Weather variables included: relative humidity, temperature, wind speed, and precipitation. Transport-related physical activity (walking) was sourced from participant-recorded travel diaries. Three-part hurdle models were used to analyze the data. Results indicate statistically or substantively insignificant correlations between the weather variables and transport-related physical activity for all destination types. These results provide the strongest evidence to date that transport-related physical activity may occur relatively independently of weather conditions. The knowledge that weather conditions do not seem to be a significant barrier to this domain of activity may potentially expand the universe of geographic locations that are amenable to environmental and programmatic interventions to increase transport-related walking. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Is manual wheelchair satisfaction related to active lifestyle and participation in people with a spinal cord injury?

    Science.gov (United States)

    de Groot, S; Post, M W M; Bongers-Janssen, H M H; Bloemen-Vrencken, J H; van der Woude, L H V

    2011-04-01

    Cross-sectional study. To describe the satisfaction of the manual wheelchair user with hand rim wheelchair-related aspects (for example, dimensions, weight and comfort) and wheelchair service-related aspects and to determine the relationship between wheelchair users' satisfaction, personal and lesion characteristics, and active lifestyle and participation in persons with a spinal cord injury (SCI). Eight Dutch rehabilitation centers with a specialized SCI unit. The Dutch version of the Quebec user evaluation of satisfaction with assistive technology (D-QUEST) was filled out by 109 participants 1 year after discharge from inpatient SCI rehabilitation. Relationships between the D-QUEST scores and personal and lesion characteristics, and active lifestyle and participation (physical activity scale for individuals with physical disabilities (PASIPD), Utrecht activity list (UAL), mobility range and social behavior subscales of the SIP68 (SIPSOC)) were determined. A high level of satisfaction was found with wheelchair-related aspects. The participants were less satisfied with the service-related aspects. Participants with an incomplete lesion were slightly more satisfied regarding both aspects than those with a complete lesion. A higher satisfaction regarding wheelchair dimensions and a higher overall satisfaction were related to a more active lifestyle. Persons who were more satisfied with the simplicity of use of the wheelchair had a better participation score. Dutch persons with SCI are in general quite satisfied with their hand rim wheelchair. Some aspects of the wheelchair (dimensions and simplicity of use) are important to optimize as these are related to an active lifestyle and participation.

  9. Tannins and Tannin-Related Derivatives Enhance the (Pseudo-)Halogenating Activity of Lactoperoxidase.

    Science.gov (United States)

    Gau, Jana; Prévost, Martine; Van Antwerpen, Pierre; Sarosi, Menyhárt-Botond; Rodewald, Steffen; Arnhold, Jürgen; Flemmig, Jörg

    2017-05-26

    Several hydrolyzable tannins, proanthocyanidins, tannin derivatives, and a tannin-rich plant extract of tormentil rhizome were tested for their potential to regenerate the (pseudo-)halogenating activity, i.e., the oxidation of SCN - to hypothiocyanite - OSCN, of lactoperoxidase (LPO) after hydrogen peroxide-mediated enzyme inactivation. Measurements were performed using 5-thio-2-nitrobenzoic acid in the presence of tannins and related substances in order to determine kinetic parameters and to trace the LPO-mediated - OSCN formation. The results were combined with docking studies and molecular orbital analysis. The - OSCN-regenerating effect of tannin derivatives relates well with their binding properties toward LPO as well as their occupied molecular orbitals. Especially simple compounds like ellagic acid or methyl gallate and the complex plant extract were found as potent enzyme-regenerating compounds. As the (pseudo-)halogenating activity of LPO contributes to the maintenance of oral bacterial homeostasis, the results provide new insights into the antibacterial mode of action of tannins and related compounds. Furthermore, chemical properties of the tested compounds that are important for efficient enzyme-substrate interaction and regeneration of the - OSCN formation by LPO were identified.

  10. Making access to TV contingent on physical activity: effects on liking and relative reinforcing value of TV and physical activity in overweight and obese children.

    Science.gov (United States)

    Goldfield, Gary S

    2012-02-01

    This study examined the effects of making access to television (TV) viewing contingent on physical activity on the liking and reinforcing value of TV and attitudes towards physical activity in overweight and obese children. Secondary data analysis from a randomized controlled trial designed to increase physical activity and reduce TV viewing in 30, 8-12 years old overweight or obese children by making access to TV contingent on physical activity (intervention) or free access to TV (control). Liking of TV and physical activity was measured by a 100 point visual analog scale, while the relative reinforcing value of TV in relation to physical activity was assessed using a questionnaire based on behavioural choice paradigm that provided children an opportunity to work (button presses) to gain access to TV or physical activity according to a progressive ratio schedule of reinforcement. Enjoyment, Adequacy, Predilection and Motivation for physical activity was assessed by self-report questionnaire. Making access to TV contingent on physical activity showed a trend that approached statistical significance towards increased enjoyment of physical activity and did not adversely affect change in the liking or the relative reinforcing value of TV viewing. Making access to TV contingent on physical activity had no adverse effects on the liking or reinforcing value of TV and even showed a suggestive effect of increased enjoyment of physical activity. Thus, given this intervention markedly increased physical activity and reduced TV viewing in overweight and obese children, long-term evaluations of this interventions to assess sustainability of these behavioral changes and associated health benefits are warranted.

  11. Disentangling brain activity related to the processing of emotional visual information and emotional arousal.

    Science.gov (United States)

    Kuniecki, Michał; Wołoszyn, Kinga; Domagalik, Aleksandra; Pilarczyk, Joanna

    2018-05-01

    Processing of emotional visual information engages cognitive functions and induces arousal. We aimed to examine the modulatory role of emotional valence on brain activations linked to the processing of visual information and those linked to arousal. Participants were scanned and their pupil size was measured while viewing negative and neutral images. The visual noise was added to the images in various proportions to parametrically manipulate the amount of visual information. Pupil size was used as an index of physiological arousal. We show that arousal induced by the negative images, as compared to the neutral ones, is primarily related to greater amygdala activity while increasing visibility of negative content to enhanced activity in the lateral occipital complex (LOC). We argue that more intense visual processing of negative scenes can occur irrespective of the level of arousal. It may suggest that higher areas of the visual stream are fine-tuned to process emotionally relevant objects. Both arousal and processing of emotional visual information modulated activity within the ventromedial prefrontal cortex (vmPFC). Overlapping activations within the vmPFC may reflect the integration of these aspects of emotional processing. Additionally, we show that emotionally-evoked pupil dilations are related to activations in the amygdala, vmPFC, and LOC.

  12. The meaning of activities in the dwelling and residential environment : A structural approach in people-environment relations.

    NARCIS (Netherlands)

    Meesters, J.

    2009-01-01

    The dwelling is a central setting in people’s everyday life. People use their dwelling and residential environment for a large variety of activities and purposes. This study systematically relates activities, settings and meanings to improve the insight into people-environment relations. This is

  13. Spectroscopic diagnostic of gold plasma

    Energy Technology Data Exchange (ETDEWEB)

    Busquet, M.

    1986-06-01

    Results of a simulation of a gold-aluminium alloy target irradiated by laser are presented. FCI code has been used with a processing out of LTE of atomic physics of gold and of multigroup photonics. Emission and reabsorption of gold and aluminium lines are included.

  14. 76 FR 11756 - Action Affecting Export Privileges; Ali Amirnazmi; Order Denying Export Privileges

    Science.gov (United States)

    2011-03-03

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; Ali Amirnazmi; Order Denying Export Privileges In the Matter of: Ali Amirnazmi, Register 63302-066, FCI... release and forfeit $81,277.37. Section 766.25 of the Export Administration Regulations (``EAR'' or...

  15. Coping with Separation: An Analysis of Outcomes and Strategies Used by Working and Nonworking Wives during Routine Deployment. Part A

    Science.gov (United States)

    1987-06-22

    of approaching problems) and specfic coping efforts (behavioral or intra- psychic action taken in situations that are aimed at reducing stress... unemployed . Military Medicine, 1981, 146, 10. * I McCubbin, H.I., Boss, P., Wilson, L. & Dahl, B. Family Coping Inventory WI (FCI). In Family

  16. Survival of Bemisia tabaci and activity of plant defense-related enzymes in genotypes of Capsicum annuum L.

    Directory of Open Access Journals (Sweden)

    Luis Latournerie-Moreno

    2015-03-01

    Full Text Available The whitefly Bemisia tabaci (Gennadius, 1889 is a major plant pest of horticultural crops from the families Solanaceae, Fabaceae and Cucurbitaceae in Neotropical areas. The exploration of host plant resistance and their biochemical mechanisms offers an excellent alternative to better understand factors affecting the interaction between phytophagous insect and host plant. We evaluated the survival of B. tabaci in landrace genotypes of Capsicum annuum L., and the activity of plant defense-related enzymes (chitinase, polyphenoloxidase, and peroxidase. The landrace genotypes Amaxito, Tabaquero, and Simojovel showed resistance to B. tabaci, as we observed more than 50% nymphal mortality, while in the commercial susceptible genotype Jalapeño mortality of B. tabaci nymphs was not higher than 20%. The activities of plant defense-related enzymes were significantly different among pepper genotypes (P < 0.05. Basal activities of chitinase, polyphenoloxidase and peroxidase were significantly lower or equal in landrace genotypes than that of the commercial genotype Jalapeño. The activity of plant enzymes was differential among pepper genotypes (P < 0.05. For example, the activity of chitinase enzyme generally was higher in non-infested plants with B. tabaci than those infested. Instead polyphenoloxidase ('Amaxito' and 'Simojovel' and peroxidase enzymes activities ('Tabaquero' increased in infested plants (P < 0.05. We conclude that basal activities of plant defense-related enzymes could be act through other mechanism plant induction, since plant defense-related enzymes showed a different induction response to B. tabaci. We underlined the role of polyphenoloxidase as plant defense in the pepper genotype Simojovel related to B. tabaci.

  17. Personal, social, and game-related correlates of active and non-active gaming among dutch gaming adolescents: survey-based multivariable, multilevel logistic regression analyses.

    Science.gov (United States)

    Simons, Monique; de Vet, Emely; Chinapaw, Mai Jm; de Boer, Michiel; Seidell, Jacob C; Brug, Johannes

    2014-04-04

    Playing video games contributes substantially to sedentary behavior in youth. A new generation of video games-active games-seems to be a promising alternative to sedentary games to promote physical activity and reduce sedentary behavior. At this time, little is known about correlates of active and non-active gaming among adolescents. The objective of this study was to examine potential personal, social, and game-related correlates of both active and non-active gaming in adolescents. A survey assessing game behavior and potential personal, social, and game-related correlates was conducted among adolescents (12-16 years, N=353) recruited via schools. Multivariable, multilevel logistic regression analyses, adjusted for demographics (age, sex and educational level of adolescents), were conducted to examine personal, social, and game-related correlates of active gaming ≥1 hour per week (h/wk) and non-active gaming >7 h/wk. Active gaming ≥1 h/wk was significantly associated with a more positive attitude toward active gaming (OR 5.3, CI 2.4-11.8; Pgames (OR 0.30, CI 0.1-0.6; P=.002), a higher score on habit strength regarding gaming (OR 1.9, CI 1.2-3.2; P=.008) and having brothers/sisters (OR 6.7, CI 2.6-17.1; Pgame engagement (OR 0.95, CI 0.91-0.997; P=.04). Non-active gaming >7 h/wk was significantly associated with a more positive attitude toward non-active gaming (OR 2.6, CI 1.1-6.3; P=.035), a stronger habit regarding gaming (OR 3.0, CI 1.7-5.3; P7 h/wk. Active gaming is most strongly (negatively) associated with attitude with respect to non-active games, followed by observed active game behavior of brothers and sisters and attitude with respect to active gaming (positive associations). On the other hand, non-active gaming is most strongly associated with observed non-active game behavior of friends, habit strength regarding gaming and attitude toward non-active gaming (positive associations). Habit strength was a correlate of both active and non-active gaming

  18. Personal, Social, and Game-Related Correlates of Active and Non-Active Gaming Among Dutch Gaming Adolescents: Survey-Based Multivariable, Multilevel Logistic Regression Analyses

    Science.gov (United States)

    de Vet, Emely; Chinapaw, Mai JM; de Boer, Michiel; Seidell, Jacob C; Brug, Johannes

    2014-01-01

    Background Playing video games contributes substantially to sedentary behavior in youth. A new generation of video games—active games—seems to be a promising alternative to sedentary games to promote physical activity and reduce sedentary behavior. At this time, little is known about correlates of active and non-active gaming among adolescents. Objective The objective of this study was to examine potential personal, social, and game-related correlates of both active and non-active gaming in adolescents. Methods A survey assessing game behavior and potential personal, social, and game-related correlates was conducted among adolescents (12-16 years, N=353) recruited via schools. Multivariable, multilevel logistic regression analyses, adjusted for demographics (age, sex and educational level of adolescents), were conducted to examine personal, social, and game-related correlates of active gaming ≥1 hour per week (h/wk) and non-active gaming >7 h/wk. Results Active gaming ≥1 h/wk was significantly associated with a more positive attitude toward active gaming (OR 5.3, CI 2.4-11.8; Pgames (OR 0.30, CI 0.1-0.6; P=.002), a higher score on habit strength regarding gaming (OR 1.9, CI 1.2-3.2; P=.008) and having brothers/sisters (OR 6.7, CI 2.6-17.1; Pgame engagement (OR 0.95, CI 0.91-0.997; P=.04). Non-active gaming >7 h/wk was significantly associated with a more positive attitude toward non-active gaming (OR 2.6, CI 1.1-6.3; P=.035), a stronger habit regarding gaming (OR 3.0, CI 1.7-5.3; P7 h/wk. Active gaming is most strongly (negatively) associated with attitude with respect to non-active games, followed by observed active game behavior of brothers and sisters and attitude with respect to active gaming (positive associations). On the other hand, non-active gaming is most strongly associated with observed non-active game behavior of friends, habit strength regarding gaming and attitude toward non-active gaming (positive associations). Habit strength was a

  19. Recommended level of physical activity and health-related quality of life among Japanese adults

    OpenAIRE

    Nakamura Yoshio; Oka Koichiro; Shibata Ai; Muraoka Isao

    2007-01-01

    Abstract Background The benefits of a recommended level of physical activity on physiological health indicators such as morbidity and mortality are well-accepted, but less research has addressed whether or not the association between the recommended level of physical activity and a health-related quality of life (HRQOL) exists in the Japanese population. Thus, the present study examined whether the recommended physical activity would be associated with HRQOL in the general Japanese middle-age...

  20. Ground Deformation Related to Caldera Collapse and Ring-Fault Activity

    KAUST Repository

    Liu, Yuan-Kai

    2018-05-01

    Volcanic subsidence, caused by partial emptying of magma in the subsurface reservoir has long been observed by spaceborne radar interferometry. Monitoring long-term crustal deformation at the most notable type of volcanic subsidence, caldera, gives us insights of the spatial and hazard-related information of subsurface reservoir. Several subsiding calderas, such as volcanoes on the Galapagos islands have shown a complex ground deformation pattern, which is often composed of a broad deflation signal affecting the entire edifice and a localized subsidence signal focused within the caldera floor. Although numerical or analytical models with multiple reservoirs are proposed as the interpretation, geologically and geophysically evidenced ring structures in the subsurface are often ignored. Therefore, it is still debatable how deep mechanisms relate to the observed deformation patterns near the surface. We aim to understand what kind of activities can lead to the complex deformation. Using two complementary approaches, we study the three-dimensional geometry and kinematics of deflation processes evolving from initial subsidence to later collapse of calderas. Firstly, the analog experiments analyzed by structure-from-motion photogrammetry (SfM) and particle image velocimetry (PIV) helps us to relate the surface deformation to the in-depth structures. Secondly, the numerical modeling using boundary element method (BEM) simulates the characteristic deformation patterns caused by a sill-like source and a ring-fault. Our results show that the volcano-wide broad deflation is primarily caused by the emptying of the deep magma reservoir, whereas the localized deformation on the caldera floor is related to ring-faulting at a shallower depth. The architecture of the ring-fault to a large extent determines the deformation localization on the surface. Since series evidence for ring-faulting at several volcanoes are provided, we highlight that it is vital to include ring

  1. Ground Deformation Related to Caldera Collapse and Ring-Fault Activity

    KAUST Repository

    Liu, Yuan-Kai

    2018-01-01

    Volcanic subsidence, caused by partial emptying of magma in the subsurface reservoir has long been observed by spaceborne radar interferometry. Monitoring long-term crustal deformation at the most notable type of volcanic subsidence, caldera, gives us insights of the spatial and hazard-related information of subsurface reservoir. Several subsiding calderas, such as volcanoes on the Galapagos islands have shown a complex ground deformation pattern, which is often composed of a broad deflation signal affecting the entire edifice and a localized subsidence signal focused within the caldera floor. Although numerical or analytical models with multiple reservoirs are proposed as the interpretation, geologically and geophysically evidenced ring structures in the subsurface are often ignored. Therefore, it is still debatable how deep mechanisms relate to the observed deformation patterns near the surface. We aim to understand what kind of activities can lead to the complex deformation. Using two complementary approaches, we study the three-dimensional geometry and kinematics of deflation processes evolving from initial subsidence to later collapse of calderas. Firstly, the analog experiments analyzed by structure-from-motion photogrammetry (SfM) and particle image velocimetry (PIV) helps us to relate the surface deformation to the in-depth structures. Secondly, the numerical modeling using boundary element method (BEM) simulates the characteristic deformation patterns caused by a sill-like source and a ring-fault. Our results show that the volcano-wide broad deflation is primarily caused by the emptying of the deep magma reservoir, whereas the localized deformation on the caldera floor is related to ring-faulting at a shallower depth. The architecture of the ring-fault to a large extent determines the deformation localization on the surface. Since series evidence for ring-faulting at several volcanoes are provided, we highlight that it is vital to include ring

  2. Active assistance technology for health-related behavior change: an interdisciplinary review.

    Science.gov (United States)

    Kennedy, Catriona M; Powell, John; Payne, Thomas H; Ainsworth, John; Boyd, Alan; Buchan, Iain

    2012-06-14

    Information technology can help individuals to change their health behaviors. This is due to its potential for dynamic and unbiased information processing enabling users to monitor their own progress and be informed about risks and opportunities specific to evolving contexts and motivations. However, in many behavior change interventions, information technology is underused by treating it as a passive medium focused on efficient transmission of information and a positive user experience. To conduct an interdisciplinary literature review to determine the extent to which the active technological capabilities of dynamic and adaptive information processing are being applied in behavior change interventions and to identify their role in these interventions. We defined key categories of active technology such as semantic information processing, pattern recognition, and adaptation. We conducted the literature search using keywords derived from the categories and included studies that indicated a significant role for an active technology in health-related behavior change. In the data extraction, we looked specifically for the following technology roles: (1) dynamic adaptive tailoring of messages depending on context, (2) interactive education, (3) support for client self-monitoring of behavior change progress, and (4) novel ways in which interventions are grounded in behavior change theories using active technology. The search returned 228 potentially relevant articles, of which 41 satisfied the inclusion criteria. We found that significant research was focused on dialog systems, embodied conversational agents, and activity recognition. The most covered health topic was physical activity. The majority of the studies were early-stage research. Only 6 were randomized controlled trials, of which 4 were positive for behavior change and 5 were positive for acceptability. Empathy and relational behavior were significant research themes in dialog systems for behavior change, with

  3. ICIT activities related to tritium management

    International Nuclear Information System (INIS)

    Zamfirache, Marius; Bornea, Anisia; Stefanescu, Ioan; Ana, George; Stefan, Liviu

    2016-01-01

    Highlights: • We present the main directions of ICIT research in the field of hydrogen isotopes. • Tritium Removal Facility became a nuclear installation. • ICIT had begun the transfer of detritiation technology. - Abstract: National Research and Development Institute for Cryogenics and Isotopic Technologies (ICIT) was established in 1970 as a research focused Industrial Pilot Plant. This new Institute was created with the purpose to develop the heavy water production technology. This technology has been successfully transferred to the heavy water production plant in 1988 (with a capacity of 360 t/year). Currently, research within ICIT is focused on the following main objectives: support for the National Nuclear Program, hydrogen and fuel cells, cryogenics, environment. Within ICIT it has been built an Experimental Pilot Plant having as the main objective the development of a technology for heavy water detritiation. The purpose of this Pilot Plant is to obtain technological data and functional characteristics of specific equipment in order to design a Detritiation Facility used for Nuclear Power Plants with CANDU reactors. This work is focused on the presentation of ICIT research activities, perspectives and its capability related to water detritiation technologies and also to on issues in the field of nuclear fusion.

  4. Does erotic stimulus presentation design affect brain activation patterns? Event-related vs. blocked fMRI designs.

    Science.gov (United States)

    Bühler, Mira; Vollstädt-Klein, Sabine; Klemen, Jane; Smolka, Michael N

    2008-07-22

    Existing brain imaging studies, investigating sexual arousal via the presentation of erotic pictures or film excerpts, have mainly used blocked designs with long stimulus presentation times. To clarify how experimental functional magnetic resonance imaging (fMRI) design affects stimulus-induced brain activity, we compared brief event-related presentation of erotic vs. neutral stimuli with blocked presentation in 10 male volunteers. Brain activation differed depending on design type in only 10% of the voxels showing task related brain activity. Differences between blocked and event-related stimulus presentation were found in occipitotemporal and temporal regions (Brodmann Area (BA) 19, 37, 48), parietal areas (BA 7, 40) and areas in the frontal lobe (BA 6, 44). Our results suggest that event-related designs might be a potential alternative when the core interest is the detection of networks associated with immediate processing of erotic stimuli.Additionally, blocked, compared to event-related, stimulus presentation allows the emergence and detection of non-specific secondary processes, such as sustained attention, motor imagery and inhibition of sexual arousal.

  5. Does erotic stimulus presentation design affect brain activation patterns? Event-related vs. blocked fMRI designs

    Directory of Open Access Journals (Sweden)

    Klemen Jane

    2008-07-01

    Full Text Available Abstract Background Existing brain imaging studies, investigating sexual arousal via the presentation of erotic pictures or film excerpts, have mainly used blocked designs with long stimulus presentation times. Methods To clarify how experimental functional magnetic resonance imaging (fMRI design affects stimulus-induced brain activity, we compared brief event-related presentation of erotic vs. neutral stimuli with blocked presentation in 10 male volunteers. Results Brain activation differed depending on design type in only 10% of the voxels showing task related brain activity. Differences between blocked and event-related stimulus presentation were found in occipitotemporal and temporal regions (Brodmann Area (BA 19, 37, 48, parietal areas (BA 7, 40 and areas in the frontal lobe (BA 6, 44. Conclusion Our results suggest that event-related designs might be a potential alternative when the core interest is the detection of networks associated with immediate processing of erotic stimuli. Additionally, blocked, compared to event-related, stimulus presentation allows the emergence and detection of non-specific secondary processes, such as sustained attention, motor imagery and inhibition of sexual arousal.

  6. Activities, self-referent memory beliefs, and cognitive performance: evidence for direct and mediated relations.

    Science.gov (United States)

    Jopp, Daniela; Hertzog, Christopher

    2007-12-01

    In this study, the authors investigated the role of activities and self-referent memory beliefs for cognitive performance in a life-span sample. A factor analysis identified 8 activity factors, including Developmental Activities, Experiential Activities, Social Activities, Physical Activities, Technology Use, Watching Television, Games, and Crafts. A second-order general activity factor was significantly related to a general factor of cognitive function as defined by ability tests. Structural regression models suggested that prediction of cognition by activity level was partially mediated by memory beliefs, controlling for age, education, health, and depressive affect. Models adding paths from general and specific activities to aspects of crystallized intelligence suggested additional unique predictive effects for some activities. In alternative models, nonsignificant effects of beliefs on activities were detected when cognition predicted both variables, consistent with the hypothesis that beliefs derive from monitoring cognition and have no influence on activity patterns. PsycINFO Database Record (c) 2008 APA, all rights reserved.

  7. Human cortical activity related to unilateral movements. A high resolution EEG study.

    Science.gov (United States)

    Urbano, A; Babiloni, C; Onorati, P; Babiloni, F

    1996-12-20

    In the present study a modern high resolution electroencephalography (EEG) technique was used to investigate the dynamic functional topography of human cortical activity related to simple unilateral internally triggered finger movements. The sensorimotor area (M1-S1) contralateral to the movement as well as the supplementary motor area (SMA) and to a lesser extent the ipsilateral M1-S1 were active during the preparation and execution of these movements. These findings suggest that both hemispheres may cooperate in both planning and production of simple unilateral volitional acts.

  8. Selective Activation Around the Left Occipito-Temporal Sulcus for Words Relative to Pictures: Individual Variability or False Positives?

    OpenAIRE

    Wright, Nicholas D; Mechelli, Andrea; Noppeney, Uta; Veltman, Dick J; Rombouts, Serge ARB; Glensman, Janice; Haynes, John-Dylan; Price, Cathy J

    2007-01-01

    We used high-resolution fMRI to investigate claims that learning to read results in greater left occipito-temporal (OT) activation for written words relative to pictures of objects. In the first experiment, 9/16 subjects performing a one-back task showed activation in ?1 left OT voxel for words relative to pictures (P < 0.05 uncorrected). In a second experiment, another 9/15 subjects performing a semantic decision task activated ?1 left OT voxel for words relative to pictures. However, at thi...

  9. Singing-Related Activity in Anterior Forebrain of Male Zebra Finches Reflects Courtship Motivation for Target Females

    Science.gov (United States)

    Iwasaki, Mai; Poulsen, Thomas M.; Oka, Kotaro; Hessler, Neal A.

    2013-01-01

    A critical function of singing by male songbirds is to attract a female mate. Previous studies have suggested that the anterior forebrain system is involved in this courtship behavior. Neural activity in this system, including the striatal Area X, is strikingly dependent on the function of male singing. When males sing to attract a female bird rather than while alone, less variable neural activity results in less variable song spectral features, which may be attractive to the female. These characteristics of neural activity and singing thus may reflect a male's motivation for courtship. Here, we compared the variability of neural activity and song features between courtship singing directed to a female with whom a male had previously formed a pair-bond or to other females. Surprisingly, across all units, there was no clear tendency for a difference in variability of neural activity or song features between courtship of paired females, nonpaired females, or dummy females. However, across the population of recordings, there was a significant relationship between the relative variability of syllable frequency and neural activity: when syllable frequency was less variable to paired than nonpaired females, neural activity was also less variable (and vice-versa). These results show that the lower variability of neural activity and syllable frequency during directed singing is not a binary distinction from undirected singing, but can vary in intensity, possibly related to the relative preference of a male for his singing target. PMID:24312344

  10. Consumer response to healthy eating, physical activity and weight-related recommendations: a systematic review.

    Science.gov (United States)

    Boylan, S; Louie, J C Y; Gill, T P

    2012-07-01

    Strong evidence linking poor diet and lack of physical activity to risk of obesity and related chronic disease has supported the development and promotion of guidelines to improve population health. Still, obesity continues to escalate as a major health concern, and so the impact of weight-related guidelines on behaviour is unclear. The aim of this review was to examine consumer response to weight-related guidelines. A systematic literature search was performed using Medline, PsycInfo, ProQuest Central and additional searches using Google and reference lists. Of the 1,765 articles identified, 46 relevant titles were included. Most studies examined attitudes towards content, source, tailoring and comprehension of dietary guidelines. Many respondents reported that guidelines were confusing, and that simple, clear, specific, realistic, and in some cases, tailored guidelines are required. Recognition of guidelines did not signify understanding nor did perceived credibility of a source guarantee utilization of guidelines. There was a lack of studies assessing: the impact of guidelines on behaviour; responses to physical activity guidelines; responses among males and studies undertaken in developing countries. Further research is needed, in particular regarding responses to physical activity guidelines and guidelines in different populations. Communication professionals should assist health professionals in the development of accurate and effective weight-related guidelines. © 2012 The Authors. obesity reviews © 2012 International Association for the Study of Obesity.

  11. Decoupled choice-driven and stimulus-related activity in parietal neurons may be misrepresented by choice probabilities.

    Science.gov (United States)

    Zaidel, Adam; DeAngelis, Gregory C; Angelaki, Dora E

    2017-09-28

    Trial-by-trial correlations between neural responses and choices (choice probabilities) are often interpreted to reflect a causal contribution of neurons to task performance. However, choice probabilities may arise from top-down, rather than bottom-up, signals. We isolated distinct sensory and decision contributions to single-unit activity recorded from the dorsal medial superior temporal (MSTd) and ventral intraparietal (VIP) areas of monkeys during perception of self-motion. Superficially, neurons in both areas show similar tuning curves during task performance. However, tuning in MSTd neurons primarily reflects sensory inputs, whereas choice-related signals dominate tuning in VIP neurons. Importantly, the choice-related activity of VIP neurons is not predictable from their stimulus tuning, and these factors are often confounded in choice probability measurements. This finding was confirmed in a subset of neurons for which stimulus tuning was measured during passive fixation. Our findings reveal decoupled stimulus and choice signals in the VIP area, and challenge our understanding of choice signals in the brain.Choice-related signals in neuronal activity may reflect bottom-up sensory processes, top-down decision-related influences, or a combination of the two. Here the authors report that choice-related activity in VIP neurons is not predictable from their stimulus tuning, and that dominant choice signals can bias the standard metric of choice preference (choice probability).

  12. On the possible relations between solar activities and global seismicity in the solar cycle 20 to 23

    Energy Technology Data Exchange (ETDEWEB)

    Herdiwijaya, Dhani, E-mail: dhani@as.itb.ac.id [Astronomy Research Division and Bosscha Observatory, Faculty of Mathematics and Natural Sciences, Bandung Institute of Technology, Ganesha 10, Bandung, Indonesia 40132 (Indonesia); Arif, Johan [Geology Research Division, Faculty of Earth Sciences and Technology, Bandung Institute of Technology, Ganesha 10, Bandung, Indonesia 40132 (Indonesia); Nurzaman, Muhamad Zamzam; Astuti, Isna Kusuma Dewi [Astronomy Study Program, Faculty of Mathematics and Natural Sciences, Bandung Institute of Technology, Ganesha 10, Bandung, Indonesia 40132 (Indonesia)

    2015-09-30

    Solar activities consist of high energetic particle streams, electromagnetic radiation, magnetic and orbital gravitational forces. The well-know solar activity main indicator is the existence of sunspot which has mean variation in 11 years, named by solar cycle, allow for the above fluctuations. Solar activities are also related to the space weather affecting all planetary atmospheric variability, moreover to the Earth’s climate variability. Large extreme space and geophysical events (high magnitude earthquakes, explosive volcanic eruptions, magnetic storms, etc.) are hazards for humankind, infrastructure, economies, technology and the activities of civilization. With a growing world population, and with modern reliance on delicate technological systems, human society is becoming increasingly vulnerable to natural hazardous events. The big question arises to the relation between solar forcing energy to the Earth’s global seismic activities. Estimates are needed for the long term occurrence-rate probabilities of these extreme natural hazardous events. We studied connectivity from yearly seismic activities that refer to and sunspot number within the solar cycle 20 to 23 of year 1960 to 2013 (53 years). We found clear evidences that in general high magnitude earthquake events and their depth were related to the low solar activity.

  13. On the possible relations between solar activities and global seismicity in the solar cycle 20 to 23

    Science.gov (United States)

    Herdiwijaya, Dhani; Arif, Johan; Nurzaman, Muhamad Zamzam; Astuti, Isna Kusuma Dewi

    2015-09-01

    Solar activities consist of high energetic particle streams, electromagnetic radiation, magnetic and orbital gravitational forces. The well-know solar activity main indicator is the existence of sunspot which has mean variation in 11 years, named by solar cycle, allow for the above fluctuations. Solar activities are also related to the space weather affecting all planetary atmospheric variability, moreover to the Earth's climate variability. Large extreme space and geophysical events (high magnitude earthquakes, explosive volcanic eruptions, magnetic storms, etc.) are hazards for humankind, infrastructure, economies, technology and the activities of civilization. With a growing world population, and with modern reliance on delicate technological systems, human society is becoming increasingly vulnerable to natural hazardous events. The big question arises to the relation between solar forcing energy to the Earth's global seismic activities. Estimates are needed for the long term occurrence-rate probabilities of these extreme natural hazardous events. We studied connectivity from yearly seismic activities that refer to and sunspot number within the solar cycle 20 to 23 of year 1960 to 2013 (53 years). We found clear evidences that in general high magnitude earthquake events and their depth were related to the low solar activity.

  14. Social influence and adolescent health-related physical activity in structured and unstructured settings: role of channel and type.

    Science.gov (United States)

    Spink, Kevin S; Wilson, Kathleen S; Ulvick, Jocelyn

    2012-08-01

    Social influence channels (e.g., parents) and types (e.g., compliance) have each been related to physical activity independently, but little is known about how these two categories of influence may operate in combination. This study examined the relationships between various combinations of social influence and physical activity among youth across structured and unstructured settings. Adolescents (N=304), classified as high or low active, reported the social influence combinations they received for being active. Participants identified three channels and three types of influence associated with being active. For structured activity, compliance with peers and significant others predicted membership in the high active group (values of psocial influence, when examining health-related physical activity.

  15. Selective activation around the left occipito-temporal sulcus for words relative to pictures: individual variability or false positives?

    Science.gov (United States)

    Wright, Nicholas D; Mechelli, Andrea; Noppeney, Uta; Veltman, Dick J; Rombouts, Serge A R B; Glensman, Janice; Haynes, John-Dylan; Price, Cathy J

    2008-08-01

    We used high-resolution fMRI to investigate claims that learning to read results in greater left occipito-temporal (OT) activation for written words relative to pictures of objects. In the first experiment, 9/16 subjects performing a one-back task showed activation in > or =1 left OT voxel for words relative to pictures (P or =1 left OT voxel for words relative to pictures. However, at this low statistical threshold false positives need to be excluded. The semantic decision paradigm was therefore repeated, within subject, in two different scanners (1.5 and 3 T). Both scanners consistently localised left OT activation for words relative to fixation and pictures relative to words, but there were no consistent effects for words relative to pictures. Finally, in a third experiment, we minimised the voxel size (1.5 x 1.5 x 1.5 mm(3)) and demonstrated a striking concordance between the voxels activated for words and pictures, irrespective of task (naming vs. one-back) or script (English vs. Hebrew). In summary, although we detected differential activation for words relative to pictures, these effects: (i) do not withstand statistical rigour; (ii) do not replicate within or between subjects; and (iii) are observed in voxels that also respond to pictures of objects. Our findings have implications for the role of left OT activation during reading. More generally, they show that studies using low statistical thresholds in single subject analyses should correct the statistical threshold for the number of comparisons made or replicate effects within subject. (c) 2007 Wiley-Liss, Inc.

  16. Imbalance of incidental encoding across tasks: an explanation for non-memory-related hippocampal activations?

    Science.gov (United States)

    Reas, Emilie T; Brewer, James B

    2013-11-01

    Functional neuroimaging studies have increasingly noted hippocampal activation associated with a variety of cognitive functions--such as decision making, attention, perception, incidental learning, prediction, and working memory--that have little apparent relation to declarative memory. Such findings might be difficult to reconcile with classical hippocampal lesion studies that show remarkable sparing of cognitive functions outside the realm of declarative memory. Even the oft-reported hippocampal activations during confident episodic retrieval are not entirely congruent with evidence that hippocampal lesions reliably impair encoding but inconsistently affect retrieval. Here we explore the conditions under which the hippocampus responds during episodic recall and recognition. Our findings suggest that anterior hippocampal activity may be related to the imbalance of incidental encoding across tasks and conditions rather than due to retrieval per se. Incidental encoding and hippocampal activity may be reduced during conditions where retrieval requires greater attentional engagement. During retrieval, anterior hippocampal activity decreases with increasing search duration and retrieval effort, and this deactivation corresponds with a coincident impaired encoding of the external environment (Israel, Seibert, Black, & Brewer, 2010; Reas & Brewer, 2013; Reas, Gimbel, Hales, & Brewer, 2011). In light of this emerging evidence, we discuss the proposal that some hippocampal activity observed during memory retrieval, or other non-memory conditions, may in fact be attributable to concomitant encoding activity that is regulated by the attentional demands of the principal task. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  17. Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention

    OpenAIRE

    Andrew T. Ludlow; Stephen M. Roth

    2011-01-01

    Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence of the molecular and cellular factors associated with reduced disease risk and increased longevity resulting from physical activity is sparse. A long-standing hypothesis of aging is the telomere hypothesis: as a cell divides, telomeres shorten resulting eventually in replicative senescence and...

  18. Alcohol-Related Facebook Activity Predicts Alcohol Use Patterns in College Students

    Science.gov (United States)

    Marczinski, Cecile A.; Hertzenberg, Heather; Goddard, Perilou; Maloney, Sarah F.; Stamates, Amy L.; O’Connor, Kathleen

    2016-01-01

    The purpose of this study was to determine if a brief 10-item alcohol-related Facebook® activity (ARFA) questionnaire would predict alcohol use patterns in college students (N = 146). During a single laboratory session, participants first privately logged on to their Facebook® profiles while they completed the ARFA measure, which queries past 30 day postings related to alcohol use and intoxication. Participants were then asked to complete five additional questionnaires: three measures of alcohol use (the Alcohol Use Disorders Identification Test [AUDIT], the Timeline Follow-Back [TLFB], and the Personal Drinking Habits Questionnaire [PDHQ]), the Barratt Impulsiveness Scale (BIS-11), and the Marlowe-Crowne Social Desirability Scale (MC-SDS). Regression analyses revealed that total ARFA scores were significant predictors of recent drinking behaviors, as assessed by the AUDIT, TLFB, and PDHQ measures. Moreover, impulsivity (BIS-11) and social desirability (MC-SDS) did not predict recent drinking behaviors when ARFA total scores were included in the regressions. The findings suggest that social media activity measured via the ARFA scale may be useful as a research tool for identifying risky alcohol use. PMID:28138317

  19. Domain-specific physical activity and health-related quality of life in university students.

    Science.gov (United States)

    Pedišić, Zeljko; Rakovac, Marija; Titze, Sylvia; Jurakić, Danijel; Oja, Pekka

    2014-01-01

    Information on the relationship between domain-specific physical activity (PA) and health-related quality of life (HRQoL) in the general population and specific groups is still scarce. The aim of this study was to determine the relationship between PA in work, transport, domestic and leisure-time domains and HRQoL among university students. PA and HRQoL were assessed in a random stratified sample of 1750 university students using the International Physical Activity Questionnaire - long form and 12-item Short Form Health Survey, respectively. The Spearman's rank correlations, adjusted for age, community size, personal monthly budget, body mass index, smoking habits and alcohol intake ranged from -0.11 to 0.18 in female students and -0.29 to 0.19 in male students. Leisure-time, domestic, transport-related PA and total PA were positively related to HRQoL. Inverse correlations with HRQoL were only found for work-related PA in male students. Multiple linear regression analysis showed that only leisure-time PA was related to the Physical Summary Component score (β = 0.08 for females and β = 0.10 for males, P leisure-time, transport and domestic PA with HRQoL can potentially be used to support evidence-based promotion of PA in a university setting, and as a hypothesis for future longitudinal studies on such potential causal relationships.

  20. The relation of close friends to cognitive performance in old age: the mediating role of leisure activities.

    Science.gov (United States)

    Ihle, Andreas; Oris, Michel; Baeriswyl, Marie; Kliegel, Matthias

    2018-06-01

    ABSTRACTBackground:From a conceptual point of view, close friends are an important resource for promoting activity engagement in old age. Leisure activity engagement in turn is a key predictor of cognitive performance. Empirically, it remains unclear so far whether leisure activity engagement mediates between having close friends on the one hand and cognitive performance on the other, which we investigated in a large sample of older adults. We assessed cognitive performance (Mill Hill vocabulary scale and Trail Making Test (TMT) parts A and B) in 2,812 older adults. Participants reported information on leisure activity engagement and close friends. A larger number of leisure activities and a larger number of close friends were significantly related to better cognitive performance in the Mill Hill vocabulary scale and TMT parts A and B. A larger number of close friends were significantly related to a larger number of leisure activities. The number of leisure activities mediated more than half of the relation of the number of close friends to performance in all three cognitive measures. Having close friends may be helpful to stimulate and promote activity participation in old age. By enhancing individuals' cognitive reserve, this may finally preserve their cognitive performance level in old age.

  1. Evolution of public relations in the activity of organizations of ukrainian socio-cultural sphere

    Directory of Open Access Journals (Sweden)

    Євгенія Олегівна Кияниця

    2015-04-01

    Full Text Available The article traces the evolution of public relations in various fields of life including socio-cultural and found creative and social potential of this activity. Analysis of historical experience of using the PR-technologies in the field of sociocultural institutions promotes understanding of importance of this activity for the efficient work of organizations of this sphere

  2. Hungarian national report on activities related to operator support systems for nuclear power plants

    International Nuclear Information System (INIS)

    Adorjan, F.; Lux, I.; Vegh, J.; Vegh, E.

    1996-01-01

    Computerized operator support systems and related activities in Hungary are summarized. Systems developed in the past, presently developed and used as well as being in a planning phase are briefly described. Activity of the Hungarian participants in the framework of the co-ordinated project on operator support systems for nuclear power plant is summarized. (author). 55 refs

  3. The ferroelectric phase transition and modulated valence electrons in the incommensurate phase of ammonium tetrafluoroberyllate

    Czech Academy of Sciences Publication Activity Database

    Palatinus, Lukáš; van Smaalen, S.

    2004-01-01

    Roč. 305, - (2004), s. 49-52 ISSN 0015-0193 Grant - others:DFG and FCI(DE) XX Institutional research plan: CEZ:AV0Z1010914 Keywords : Maximum Entropy Method * modulated structures * charge density Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.517, year: 2004

  4. Applications of the Maximum Entropy Method in superspace

    Czech Academy of Sciences Publication Activity Database

    van Smaalen, S.; Palatinus, Lukáš

    2004-01-01

    Roč. 305, - (2004), s. 57-62 ISSN 0015-0193 Grant - others:DFG and FCI(DE) XX Institutional research plan: CEZ:AV0Z1010914 Keywords : Maximum Entropy Method * modulated structures * charge density Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.517, year: 2004

  5. Spectroscopic diagnostic of gold plasma

    International Nuclear Information System (INIS)

    Busquet, M.

    1986-01-01

    Results of a simulation of a gold-aluminium alloy target irradiated by laser are presented. FCI code has been used with a processing out of LTE of atomic physics of gold and of multigroup photonics. Emission and reabsorption of gold and aluminium lines are included [fr

  6. Investigation of some factors related to antibacterial activity of Saudi honey

    International Nuclear Information System (INIS)

    Al-Brahim, Jehan Saud Rashid

    2006-01-01

    Honey was found to have a curing effect on bacterial species known to cause wound infections. The aim of this research was to study some of the factors related to the antibacterial activity of a Saudi Honey. Honey samples from different floral sources, geographic locations and production season were used. The tested organisms presented both gram positive and gram negative bacteria causing wound infection. A zone of complete inhibition of all bacterial species was observed with honey types Samra (S-W), Samra (W-S), Saha (W-S), Samra (S-S), Sidir (S-W) and a larger zone of partial inhibition of growth was observed in all tested honey types. It can be concluded that osmolarity is involved in the antibacterial activity of the honey. Acidity might be regarded as being of primary importance. On the other hand, hydrogen peroxide was found to play a major role in the bacterial activity of honey. (author)

  7. Public relations activities of the Service Hall for Kashiwazaki-Kariwa Nuclear Power Station

    International Nuclear Information System (INIS)

    Kono, T.

    1998-01-01

    This article includes information of the Service Hall for Kashiwazaki-Kariwa Nuclear Power Station. About 30% of the total electricity production in Japan is due to 16 power stations and 52 reactors. The service hall is a kind of atomic power pavilion for public relations. In Japan, each nuclear power station has such a pavilion, which acts a a center of public relations activities for the atomic power. (S. Grainger)

  8. cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.

    Science.gov (United States)

    Kerur, Nagaraj; Fukuda, Shinichi; Banerjee, Daipayan; Kim, Younghee; Fu, Dongxu; Apicella, Ivana; Varshney, Akhil; Yasuma, Reo; Fowler, Benjamin J; Baghdasaryan, Elmira; Marion, Kenneth M; Huang, Xiwen; Yasuma, Tetsuhiro; Hirano, Yoshio; Serbulea, Vlad; Ambati, Meenakshi; Ambati, Vidya L; Kajiwara, Yuji; Ambati, Kameshwari; Hirahara, Shuichiro; Bastos-Carvalho, Ana; Ogura, Yuichiro; Terasaki, Hiroko; Oshika, Tetsuro; Kim, Kyung Bo; Hinton, David R; Leitinger, Norbert; Cambier, John C; Buxbaum, Joseph D; Kenney, M Cristina; Jazwinski, S Michal; Nagai, Hiroshi; Hara, Isao; West, A Phillip; Fitzgerald, Katherine A; Sadda, SriniVas R; Gelfand, Bradley D; Ambati, Jayakrishna

    2018-01-01

    Geographic atrophy is a blinding form of age-related macular degeneration characterized by retinal pigmented epithelium (RPE) death; the RPE also exhibits DICER1 deficiency, resultant accumulation of endogenous Alu-retroelement RNA, and NLRP3-inflammasome activation. How the inflammasome is activated in this untreatable disease is largely unknown. Here we demonstrate that RPE degeneration in human-cell-culture and mouse models is driven by a noncanonical-inflammasome pathway that activates caspase-4 (caspase-11 in mice) and caspase-1, and requires cyclic GMP-AMP synthase (cGAS)-dependent interferon-β production and gasdermin D-dependent interleukin-18 secretion. Decreased DICER1 levels or Alu-RNA accumulation triggers cytosolic escape of mitochondrial DNA, which engages cGAS. Moreover, caspase-4, gasdermin D, interferon-β, and cGAS levels were elevated in the RPE in human eyes with geographic atrophy. Collectively, these data highlight an unexpected role of cGAS in responding to mobile-element transcripts, reveal cGAS-driven interferon signaling as a conduit for mitochondrial-damage-induced inflammasome activation, expand the immune-sensing repertoire of cGAS and caspase-4 to noninfectious human disease, and identify new potential targets for treatment of a major cause of blindness.

  9. Body-Related Shame and Guilt Predict Physical Activity in Breast Cancer Survivors Over Time.

    Science.gov (United States)

    Castonguay, Andrée L; Wrosch, Carsten; Pila, Eva; Sabiston, Catherine M

    2017-07-01

    To test body-related shame and guilt as predictors of breast cancer survivors' (BCS') moderate to vigorous intensity physical activity (MVPA) during six months and to examine motivational regulations as mediators of this association.
. Prospective study.
. Survivors were recruited through advertisements and oncologist referrals from medical clinics and hospitals in Montreal, Quebec, Canada.
. 149 female BCS.
. Self-reports of body-related shame and guilt, motivational regulations, and MVPA were measured among BCS at baseline. MVPA was assessed a second time six months later. Residual change scores were used.
. Body-related shame and guilt; external, introjected, and autonomous (identified and intrinsic) motivational regulations; MVPA.
. In the multiple mediation models, body-related shame was associated with low levels of MVPA, as well as external, introjected, and autonomous motivational regulations. Guilt was related to high levels of MVPA and introjected and autonomous motivational regulations. Indirect effects linked shame, guilt, and MVPA via autonomous motivation. Only body-related shame was a significant predictor of six-month changes in MVPA.
. Based on these results, the specific emotions of shame and guilt contextualized to the body differentially predict BCS' health motivations and behavior over time.
. Survivorship programs may benefit from integrating intervention strategies aimed at reducing body-related shame and helping women manage feelings of guilt to improve physical activity.

  10. The Investigation of Social Support and Physical Activity Related to Workplace among Female Teachers in Jolfa

    Directory of Open Access Journals (Sweden)

    Habibeh Sahranavard-Gargari

    2017-06-01

    Full Text Available Background and Objectives: Although active life style is one of the main determining factors of health, the amount of regular physical activities in women is less than in men and even this amount, decreases with aging. Family, friends, colleagues and society’s support, especially at workplace, have a positive effect on the amount of engagement in physical activities. The aim of this study was to investigate the status of social support and physical activity related to workplace among female teachers in Jolfa. Material and Methods: In this study, 230 female teachers working at different schools in Jolfa were selected according to the inclusion criteria. Required data were collected using International Physical Activity Questionnaire (IPAQ and social support questionnaire by Sallis et al. The data were analyzed using SPSS software. Results: The average of physical activity related to teachers’ work was about 20 minutes per week which is very low. Ten percent of them had light physical activity, 61.7% had moderate physical activity and 28.3% had heavy activity. The results of this study proved a significant relationship between social support and physical activity. Conclusion: Regarding the fact that a large percentage of the teachers do not have enough physical activity, having more physical activity and creating a social network through encouraging friends and colleagues to promote physical activity is emphasized.

  11. Culture-related differences in default network activity during visuo-spatial judgments.

    Science.gov (United States)

    Goh, Joshua O S; Hebrank, Andrew C; Sutton, Bradley P; Chee, Michael W L; Sim, Sam K Y; Park, Denise C

    2013-02-01

    Studies on culture-related differences in cognition have shown that Westerners attend more to object-related information, whereas East Asians attend more to contextual information. Neural correlates of these different culture-related visual processing styles have been reported in the ventral-visual and fronto-parietal regions. We conducted an fMRI study of East Asians and Westerners on a visuospatial judgment task that involved relative, contextual judgments, which are typically more challenging for Westerners. Participants judged the relative distances between a dot and a line in visual stimuli during task blocks and alternated finger presses during control blocks. Behaviorally, East Asians responded faster than Westerners, reflecting greater ease of the task for East Asians. In response to the greater task difficulty, Westerners showed greater neural engagement compared to East Asians in frontal, parietal, and occipital areas. Moreover, Westerners also showed greater suppression of the default network-a brain network that is suppressed under condition of high cognitive challenge. This study demonstrates for the first time that cultural differences in visual attention during a cognitive task are manifested both by differences in activation in fronto-parietal regions as well as suppression in default regions.

  12. Organized Sport Participation Is Associated with Higher Levels of Overall Health-Related Physical Activity in Children (CHAMPS Study-DK)

    Science.gov (United States)

    Hebert, Jeffrey J.; Møller, Niels C.; Andersen, Lars B.; Wedderkopp, Niels

    2015-01-01

    Introduction Many children fail to meet international guideline recommendations for health-related activity (≥60 minutes/day of moderate-to-vigorous physical activity [MVPA]), and intervention studies to date have reported negligible effects. Objective Explore the associations of organized leisure-time sport participation with overall physical activity levels and health-related physical activity guideline concordance. Methods This prospective cohort study was nested in the Childhood Health, Activity, and Motor Performance School Study Denmark. Study participants were a representative sample of 1124 primary school students. Organized leisure-time sport participation was reported via text messaging and physical activity was objectively measured over seven days with accelerometry. Associations between sport participation and physical activity level were explored with multilevel mixed-effects regression models and reported with beta coefficients (b) and adjusted odds ratios (aOR). Results Participants were 53% female, with mean(SD) age = 8.4(1.4) years. Boys were more active than girls (psports (gymnastics, basketball, volleyball) were inconsistent. Conclusions Many children, particularly girls and those in higher grade levels do not adhere to health-related physical activity recommendations. Organized leisure-time sport participation may be a viable strategy to increase overall health-related physical activity levels and international guideline concordance in children. PMID:26262678

  13. Active reward processing during human sleep: insights from sleep-related eating disorder

    Directory of Open Access Journals (Sweden)

    Lampros ePerogamvros

    2012-11-01

    Full Text Available In this paper, we present two carefully documented cases of patients with sleep-related eating disorder (SRED, a parasomnia which is characterized by involuntary compulsive eating during the night and whose pathophysiology is not known. Using video-polysomnography and psychometric examination, we found that both patients present elevated novelty seeking and increased reward sensitivity on reward-related questionnaires. In light of new evidence on the mesolimbic dopaminergic implication in compulsive eating disorders, our findings suggest a role of an active reward system during sleep in the manifestation of SRED.

  14. Role of Slovakia within the IAEA Decommissioning Related Activities

    International Nuclear Information System (INIS)

    Michal, V.; Stubna, M.

    2009-01-01

    Slovakia has a long-term experience with the IAEA decommissioning related activities as a recipient of Agency assistance and then as a country offering assistance to others. Background, short 'history' and current status of Slovakian national technical cooperation (TC) projects SLR/4/008 'Robotic Technologies for Decontamination and Decommissioning of the Bohunice A1 NPP' and SLR/3/002 'Management of Radioactive Waste from the A1 Nuclear Power Plant Decommissioning' will be described in paper. The first TC project SLR/4/008 was solved by the main Slovakian counterpart, company VUJE, Inc., from 2001 to 2006. Second TC project SLR/3/002 is ongoing with extension to 2011. Thanks to the implementation of a long-term large-scale 'Project of the A1 NPP Decommissioning - Stage I' (1996-2007), financed by Slovak National Nuclear Account (decommissioning fund), as well as implementation of the IAEA TC national projects a comprehensive know-how in the field of D and D and RAW management was obtained. Moreover, technologies and facilities necessary for implementation of decommissioning and RAW management projects were developed. Thanks to this development Slovakia offers donor assistance to other countries in subjected fields through IAEA TC program. The type and scope of assistance for Armenia, Bulgaria, Egypt, Latvia, Lithuania and The Ukraine is described in the paper. The above-mentioned national projects are not only activities of Slovakia within the IAEA TC program. Regional TC project RER/3/005 'Support in Planning the Decommissioning of Nuclear Power Plants and Research Reactors' has been ongoing from 2007 with accepted extension to 2011. About nine countries from Eastern and Central Europe participate in the project (for the NPPs part) and Slovakia plays the role of LCC (Leading Country Coordinator). On the basis of suggestion of Nuclear Regulatory Authority of the Slovak Republic, VUJE is the coordinator of the regional project. Moreover, Slovakia would be the

  15. Waste management regulatory compliance issues related to D ampersand D activities at Oak Ridge National Laboratory (ORNL)

    International Nuclear Information System (INIS)

    Hitch, J.P.; Arnold, S.E.; Burwinkle, T.; Daugherty, D.

    1994-01-01

    The waste management activities at ORNL related to the decontamination and decommissioning (D ampersand D) of radioactively contaminated buildings are divided into four categories: Operational facilities, inactive or surplus facilities, future facilities planning, and D ampersand D activities. This paper only discusses regulatory issues related to inactive or surplus facilities. Additionally, rather than attempting to address all resulting waste streams and related regulations, this paper highlights only a few of the ORNL waste streams that present key regulatory issues

  16. The Effects of Reflective Activities on Skill Adaptation in a Work-Related Instrumental Learning Setting

    Science.gov (United States)

    Roessger, Kevin M.

    2014-01-01

    In work-related instrumental learning contexts, the role of reflective activities is unclear. Kolb's experiential learning theory and Mezirow's transformative learning theory predict skill adaptation as an outcome. This prediction was tested by manipulating reflective activities and assessing participants' response and error rates during novel…

  17. Body composition of 80-years old men and women and its relation to muscle strength, physical activity and functional ability

    DEFF Research Database (Denmark)

    Pedersen, Agnes Nadelmann; Ovesen, L.; Schroll, M.

    2002-01-01

    , and physical activity and functional ability. BMI was related to body fat mass, and FFM was related to muscle strength. Muscle strength was related to mobility and PPT. Mobility and PPT were mutually related and were related to physical activity. CONCLUSION: Our cross sectional study did not support newly...

  18. DINFOS: Bibliography of Theses and Reports Related to Military Information Activities; Volume V, May 1976.

    Science.gov (United States)

    Fort Benjamin Harrison, IN. Defense Information School.

    This bibliography lists theses and research reports related to military information activities. The listings are grouped according to the following subject categories: journalism, public and internal information, mass communications, political science, international communications, sociology, history, education, public relations, leadership,…

  19. Motivation-related predictors of physical activity engagement and vitality in rheumatoid arthritis patients

    OpenAIRE

    Yu, C.-a.; Rouse, P. C.; Van Zanten, J. V. J.; Metsios, G. S.; Ntoumanis, N.; Kitas, G. D.; Duda, J. L.

    2015-01-01

    This study tests the Basic Psychological Needs Theory (within the Self-determination framework), in relation to the prediction of physical activity and well-being among rheumatoid arthritis patients. Motivation regulations for physical activity were also considered in the process model. A total of 207 patients (150 females, mean age = 58 ± 11 years) completed a questionnaire pack and structural equation modelling was used to test expected relationships. Autonomy support provided by important ...

  20. Physical Activity in Relation to Sleep Among Community-Dwelling Older Adults in China.

    Science.gov (United States)

    Li, Junxin; Yang, Binbin; Varrasse, Miranda; Ji, Xiaopeng; Wu, MaoChun; Li, Manman; Li, Kun

    2018-02-27

    This cross-sectional study was conducted to describe physical activity and sleep in 290 community-dwelling Chinese older adults and to examine the association between physical activity and poor sleep outcomes. Almost half of the sample were poor sleepers. The majority of the sample regularly participated in walking, some household activity and light sports; yet, only a small portion were involved in work-related activity or in strenuous sports. A greater level of overall physical activity [Odds Ratio (OR) =0.79, 95% confidence interval (CI) = (0.73,0.86)], leisure-time exercise [OR=0.77, 95%CI=(0.68,0.85)], and household activity [OR=0.66, 95%CI= (0.56,0.78)] were associated with reduced likelihood of being poor sleepers and other poor sleep outcomes, independent of covariates including age, sex, education, family income, the number of children, drinking, and sleep hygiene. Future larger scale studies that incorporate both objective and subjective measures are needed to further examine the association and to explore the effects of different types of activity on sleep and other well-beings in older adults.