WorldWideScience

Sample records for factors including temperature

  1. Enhanced battery model including temperature effects

    NARCIS (Netherlands)

    Rosca, B.; Wilkins, S.

    2013-01-01

    Within electric and hybrid vehicles, batteries are used to provide/buffer the energy required for driving. However, battery performance varies throughout the temperature range specific to automotive applications, and as such, models that describe this behaviour are required. This paper presents a dy

  2. Enhanced battery model including temperature effects

    NARCIS (Netherlands)

    Rosca, B.; Wilkins, S.

    2013-01-01

    Within electric and hybrid vehicles, batteries are used to provide/buffer the energy required for driving. However, battery performance varies throughout the temperature range specific to automotive applications, and as such, models that describe this behaviour are required. This paper presents a dy

  3. Enhanced battery model including temperature effects

    NARCIS (Netherlands)

    Rosca, B.; Wilkins, S.

    2013-01-01

    Within electric and hybrid vehicles, batteries are used to provide/buffer the energy required for driving. However, battery performance varies throughout the temperature range specific to automotive applications, and as such, models that describe this behaviour are required. This paper presents a

  4. Experimental Determination of the Recovery Factor and Analytical Solution of the Conical Flow Field for a 20 deg Included Angle Cone at Mach Numbers of 4.6 and 6.0 and Stagnation Temperatures to 2600 degree R

    Science.gov (United States)

    Pfyl, Frank A.; Presley, Leroy L.

    1961-01-01

    The local recovery factor was determined experimentally along the surface of a thin-walled 20 deg included angle cone for Mach numbers near 6.0 at stagnation temperatures between 1200 deg R and 2600 deg R. In addition, a similar cone configuration was tested at Mach numbers near 4.5 at stagnation temperatures of approximately 612 deg R. The local Reynolds number based on flow properties at the edge of the boundary layer ranged between 0.1 x 10(exp 4) and 3.5 x 10(exp 4) for tests at temperatures above 1200 deg R and between 6 x 10(exp 4) and 25 x 10(exp 4) for tests at temperatures near 612 deg R. The results indicated, generally, that the recovery factor can be predicted satisfactorily using the square root of the Prandtl number. No conclusion could be made as to the necessity of evaluating the Prandtl number at a reference temperature given by an empirical equation, as opposed to evaluating the Prandtl number at the wall temperature or static temperature of the gas at the cone surface. For the tests at temperatures above 1200 deg R (indicated herein as the tests conducted in the slip-flow region), two definite trends in the recovery data were observed - one of increasing recovery factor with decreasing stagnation pressure, which was associated with slip-flow effects and one of decreasing recovery factor with increasing temperature. The true cause of the latter trend could not be ascertained, but it was shown that this trend was not appreciably altered by the sources of error of the magnitude considered herein. The real-gas equations of state were used to determine accurately the local stream properties at the outer edge of the boundary layer of the cone. Included in the report, therefore, is a general solution for the conical flow of a real gas using the Beattie-Bridgeman equation of state. The largest effect of temperature was seen to be in the terms which were dependent upon the internal energy of the gas. The pressure and hence the pressure drag terms were

  5. Mixture including hydrogen and hydrocarbon having pressure-temperature stability

    Science.gov (United States)

    Mao, Wendy L. (Inventor); Mao, Ho-Kwang (Inventor)

    2009-01-01

    The invention relates to a method of storing hydrogen that employs a mixture of hydrogen and a hydrocarbon that can both be used as fuel. In one embodiment, the method involves maintaining a mixture including hydrogen and a hydrocarbon in the solid state at ambient pressure and a temperature in excess of about 10 K.

  6. Sea Surface Temperature from EUMETSAT Including Sentinel-3 SLSTR

    Science.gov (United States)

    O'Carroll, Anne; Bonekamp, Hans; Montagner, Francois; Santacesaria, Vincenzo; Tomazic, Igor

    2015-12-01

    The paper gives an overview of sea surface temperature (SST) activities at EUMETSAT including information on SST planned from the Sea and Land Surface Temperature Radiometer (SLSTR). Operational oceanography activities within the Marine Applications group at EUMETSAT continue with a focus on SST, sea surface winds, sea-ice products, radiative fluxes, significant wave height and sea surface topography. These are achieved through the mandatory, optional and third-party programmes, and for some products with the EUMETSAT Ocean and Sea-Ice Satellite Application Facility (OSI SAF). Progress towards products from sea-ice surface temperature, ocean colour products, turbidity and aerosol optical depth over water continue. Information on oceanography products from EUMETSAT can be found through the product navigator (http://navigator.eumetsat.int). EUMETSAT have been collaborating with ESA for a number of years on the development of SST for SLSTR.

  7. Risk Factors for Breast Cancer, Including Occupational Exposures

    Directory of Open Access Journals (Sweden)

    Elisabete Weiderpass

    2011-03-01

    Full Text Available The knowledge on the etiology of breast cancer has advanced substantially in recent years, and several etiological factors are now firmly established. However, very few new discoveries have been made in relation to occupational risk factors. The International Agency for Research on Cancer has evaluated over 900 different exposures or agents to-date to determine whether they are carcinogenic to humans. These evaluations are published as a series of Monographs (www.iarc.fr. For breast cancer the following substances have been classified as “carcinogenic to humans” (Group 1: alcoholic beverages, exposure to diethylstilbestrol, estrogen-progestogen contraceptives, estrogen-progestogen hormone replacement therapy and exposure to X-radiation and gamma-radiation (in special populations such as atomic bomb survivors, medical patients, and in-utero exposure. Ethylene oxide is also classified as a Group 1 carcinogen, although the evidence for carcinogenicity in epidemiologic studies, and specifically for the human breast, is limited. The classification “probably carcinogenic to humans” (Group 2A includes estrogen hormone replacement therapy, tobacco smoking, and shift work involving circadian disruption, including work as a flight attendant. If the association between shift work and breast cancer, the most common female cancer, is confirmed, shift work could become the leading cause of occupational cancer in women.

  8. Risk factors for breast cancer, including occupational exposures.

    Science.gov (United States)

    Weiderpass, Elisabete; Meo, Margrethe; Vainio, Harri

    2011-03-01

    The knowledge on the etiology of breast cancer has advanced substantially in recent years, and several etiological factors are now firmly established. However, very few new discoveries have been made in relation to occupational risk factors. The International Agency for Research on Cancer has evaluated over 900 different exposures or agents to-date to determine whether they are carcinogenic to humans. These evaluations are published as a series of Monographs (www.iarc.fr). For breast cancer the following substances have been classified as "carcinogenic to humans" (Group 1): alcoholic beverages, exposure to diethylstilbestrol, estrogen-progestogen contraceptives, estrogen-progestogen hormone replacement therapy and exposure to X-radiation and gamma-radiation (in special populations such as atomic bomb survivors, medical patients, and in-utero exposure). Ethylene oxide is also classified as a Group 1 carcinogen, although the evidence for carcinogenicity in epidemiologic studies, and specifically for the human breast, is limited. The classification "probably carcinogenic to humans" (Group 2A) includes estrogen hormone replacement therapy, tobacco smoking, and shift work involving circadian disruption, including work as a flight attendant. If the association between shift work and breast cancer, the most common female cancer, is confirmed, shift work could become the leading cause of occupational cancer in women.

  9. A sub-circuit MOSFET model with a wide temperature range including cryogenic temperature*

    Institute of Scientific and Technical Information of China (English)

    Jia Kan; Sun Weifeng; Shi Longxing

    2011-01-01

    A sub-circuit SPICE model ofa MOSFET for low temperature operation is presented. Two resistors are introduced for the freeze-out effect, and the explicit behavioral models are developed for them. The model can be used in a wide temperature range covering both cryogenic temperature and regular temperatures.

  10. Fast thermal simulations and temperature optimization for hyperthermia treatment planning, including realistic 3D vessel networks.

    Science.gov (United States)

    Kok, H P; van den Berg, C A T; Bel, A; Crezee, J

    2013-10-01

    Accurate thermal simulations in hyperthermia treatment planning require discrete modeling of large blood vessels. The very long computation time of the finite difference based DIscrete VAsculature model (DIVA) developed for this purpose is impractical for clinical applications. In this work, a fast steady-state thermal solver was developed for simulations with realistic 3D vessel networks. Additionally, an efficient temperature-based optimization method including the thermal effect of discrete vasculature was developed. The steady-state energy balance for vasculature and tissue was described by a linear system, which was solved with an iterative method on the graphical processing unit. Temperature calculations during optimization were performed by superposition of several precomputed temperature distributions, calculated with the developed thermal solver. The thermal solver and optimization were applied to a human anatomy, with the prostate being the target region, heated with the eight waveguide 70 MHz AMC-8 system. Realistic 3D pelvic vasculature was obtained from angiography. Both the arterial and venous vessel networks consisted of 174 segments and 93 endpoints with a diameter of 1.2 mm. Calculation of the steady-state temperature distribution lasted about 3.3 h with the original DIVA model, while the newly developed method took only ≈ 1-1.5 min. Temperature-based optimization with and without taking the vasculature into account showed differences in optimized waveguide power of more than a factor 2 and optimized tumor T90 differed up to ≈ 0.5°C. This shows the necessity to take discrete vasculature into account during optimization. A very fast method was developed for thermal simulations with realistic 3D vessel networks. The short simulation time allows online calculations and makes temperature optimization with realistic vasculature feasible, which is an important step forward in hyperthermia treatment planning.

  11. Perinatal risk factors including malformation; Perinatale Risikofaktoren einschliesslich Fehlbildungen

    Energy Technology Data Exchange (ETDEWEB)

    Brachner, A.; Grosche, B.

    1991-10-01

    The study gives a survey of the factors most frequently mentioned in the literature as factors likely to adversely affect a pregnancy. One essential aspect is the discussion of those factors that can be counted among the causes of malformations, as among others, prenatal radiation exposure. The study prepared within the framework of the research project `Radiobiological environmental monitoring in Bavaria` is intended to serve as a basis for a retrospective and prospective evaluation of infant mortality, perinatal conditions and occurrence of malformations in Bavaria, with the principal idea of drawing up an environment - related health survey. The study therefore, in addition to ionizing radiation also takes into account other detectable risks within the ecologic context, as e.g. industrial installations, refuse incineration plants or waste dumps, or urbanity. (orig./MG). [Deutsch] In der vorliegenden Arbeit wird ein Ueberblick ueber die haeufigsten in der Literatur beschriebenen Faktoren, die einen unguenstigen Einfluss auf den Schwangerschaftsverlauf ausueben koennen, gegeben. Ein Hauptgewicht liegt dabei auf der Beschreibung von solchen Faktoren, die mit der Induktion von Fehlbildungen in Zusammenhang gebracht werden koennen, so unter anderem auch der praenatalen Strahlenexposition. Diese Arbeit, die im Rahmen des Forschungsvorhabens `Strahlenbiologisches Umweltmonitoring Bayern` angefertigt wurde, bildet die Grundlage einer im Sinne einer umweltbezogenen Gesundheitsberichterstattung retro- bzw. prospektiv angelegten Auswertung der Saeuglingssterblichkeit, des Perinatalgeschehens und der Fehlbildungshaeufigkeit in Bayern, wobei neben der ionisierenden Strahlung als Risikofaktor auch andere im Rahmen einer oekologischen Studie erfassbare Risiken, wie beispielsweise Industrieansiedlungen, Muellverbrennungsanlagen und -deponien oder Urbanitaet beruecksichtigt werden sollen. (orig./MG).

  12. Noninvasive temperature estimation by detecting echo-strain change including thermal expansion

    Institute of Scientific and Technical Information of China (English)

    Ma Yong; Zhang Dong; Gong Xiu-Fen; Liu Xiao-Zhou; Ma Qing-Yu; Qiu Yuan-Yuan

    2007-01-01

    This article studies the feasibility of noninvasive temperature estimation by detecting echo-strain including thermal expansion in therapeutic ultrasound treatment. This technique evaluates distributions of echo-strain and temperature inside the tissue by detecting echo signals pre- and post-heating, in combination with the temperature dependence of sound speed and thermal expansion. In the computer simulation and experimental study, echo signals pre- and postheating are acquired and then the temperature elevation is evaluated by correlation analysis. Results demonstrate that this technique can effectively extend the measured temperature range up to 75℃ with an accuracy of ±2 ℃.

  13. Temperature-dependent nuclear moment of inertia including neutron-proton pairing correlations

    Energy Technology Data Exchange (ETDEWEB)

    Ami, Ismahane [Institut des Sciences et de la Technologie, Universite Yahia Fares de Medea, Ain-D heb, 26000 Medea (Algeria); Laboratoire de Physique Theorique, Faculte de Physique, USTHB, BP32, El-Alia, 16111 Bab-Ezzouar, Alger (Algeria); Belabbas, Mohamed [Faculte des Sciences et des Sciences de l' Ingenieur, Universite Hassiba Ben Bouali, BP151, 02000 Chlef (Algeria); Benhamouda, Naziha [Laboratoire de Physique Theorique, Faculte de Physique, USTHB, BP32, El-Alia, 16111 Bab-Ezzouar, Alger (Algeria); Fellah, Mohamed; Allal, Nassima-Hosni [Laboratoire de Physique Theorique, Faculte de Physique, USTHB, BP32, El-Alia, 16111 Bab-Ezzouar, Alger (Algeria); Centre de Recherche Nucleaire d Alger, COMENA, BP 399 Alger-Gare, Alger (Algeria)

    2009-07-01

    Expressions of the temperature-dependent parallel and perpendicular nuclear moments of inertia including neutron-proton pairing correlations have been established. The latter have been derived using the cranking method as well as the isovector temperature-dependent gap equations. They generalize the expressions of the usual finite-temperature BCS (FTBCS) method. The model has been applied to the schematic Richardson model. The obtained results are compared to those of the usual FTBCS approach for the pairing between like-particles.

  14. Temperature Dependence of Factors Controlling Isoprene Emissions

    Science.gov (United States)

    Duncan, Bryan N.; Yoshida, Yasuko; Damon, Megan R.; Douglass, Anne R.; Witte, Jacquelyn C.

    2009-01-01

    We investigated the relationship of variability in the formaldehyde (HCHO) columns measured by the Aura Ozone Monitoring Instrument (OMI) to isoprene emissions in the southeastern United States for 2005-2007. The data show that the inferred, regional-average isoprene emissions varied by about 22% during summer and are well correlated with temperature, which is known to influence emissions. Part of the correlation with temperature is likely associated with other causal factors that are temperature-dependent. We show that the variations in HCHO are convolved with the temperature dependence of surface ozone, which influences isoprene emissions, and the dependence of the HCHO column to mixed layer height as OMI's sensitivity to HCHO increases with altitude. Furthermore, we show that while there is an association of drought with the variation in HCHO, drought in the southeastern U.S. is convolved with temperature.

  15. Joining and fabrication techniques for high temperature structures including the first wall in fusion reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ho Jin; Lee, B. S.; Kim, K. B

    2003-09-01

    The materials for PFC's (Plasma Facing Components) in a fusion reactor are severely irradiated with fusion products in facing the high temperature plasma during the operation. The refractory materials can be maintained their excellent properties in severe operating condition by lowering surface temperature by bonding them to the high thermal conducting materials of heat sink. Hence, the joining and bonding techniques between dissimilar materials is considered to be important in case of the fusion reactor or nuclear reactor which is operated at high temperature. The first wall in the fusion reactor is heated to approximately 1000 .deg. C and irradiated severely by the plasma. In ITER, beryllium is expected as the primary armour candidate for the PFC's; other candidates including W, Mo, SiC, B4C, C/C and Si{sub 3}N{sub 4}. Since the heat affected zones in the PFC's processed by conventional welding are reported to have embrittlement and degradation in the sever operation condition, both brazing and diffusion bonding are being considered as prime candidates for the joining technique. In this report, both the materials including ceramics and the fabrication techniques including joining technique between dissimilar materials for PFC's are described. The described joining technique between the refractory materials and the dissimilar materials may be applicable for the fusion reactor and Generation-4 future nuclear reactor which are operated at high temperature and high irradiation.

  16. Comparative Analysis and Approximations of Space -Charge Formation in Langmuir Electrodes Including Temperature Effects.

    Science.gov (United States)

    Valdeblànquez, Eder

    2001-10-01

    Eder Valdeblànquez,Universidad del Zulia,Apartado 4011-A 526,Maracaibo,Venezuela. ABSTRACT: In this paper by space charge effect in Langmuir probes are compared for different kind of symmetries; plane, cylindrical and spherical. A detailed analysis is performed here including temperature effects, and therefore kinetic theory is used instead of fluid equations as other authors. The strongly non-linear equations obtained here have been solved first by numerical analysis and later by approximations using Bessel functions. The accuracy of each approximaton is also discussed. Space Charge effects are important in plane geometries than in the case of cylindrical or spherical symmetries.

  17. Fever in trauma patients: evaluation of risk factors, including traumatic brain injury.

    Science.gov (United States)

    Bengualid, Victoria; Talari, Goutham; Rubin, David; Albaeni, Aiham; Ciubotaru, Ronald L; Berger, Judith

    2015-03-01

    The role of fever in trauma patients remains unclear. Fever occurs as a response to release of cytokines and prostaglandins by white blood cells. Many factors, including trauma, can trigger release of these factors. To determine whether (1) fever in the first 48 hours is related to a favorable outcome in trauma patients and (2) fever is more common in patients with head trauma. Retrospective study of trauma patients admitted to the intensive care unit for at least 2 days. Data were analyzed by using multivariate analysis. Of 162 patients studied, 40% had fever during the first 48 hours. Febrile patients had higher mortality rates than did afebrile patients. When adjusted for severity of injuries, fever did not correlate with mortality. Neither the incidence of fever in the first 48 hours after admission to the intensive care unit nor the number of days febrile in the unit differed between patients with and patients without head trauma (traumatic brain injury). About 70% of febrile patients did not have a source found for their fever. Febrile patients without an identified source of infection had lower peak white blood cell counts, lower maximum body temperature, and higher minimum platelet counts than did febrile patients who had an infectious source identified. The most common infection was pneumonia. No relationship was found between the presence of fever during the first 48 hours and mortality. Patients with traumatic brain injury did not have a higher incidence of fever than did patients without traumatic brain injury. About 30% of febrile patients had an identifiable source of infection. Further studies are needed to understand the origin and role of fever in trauma patients. ©2015 American Association of Critical-Care Nurses.

  18. Resource and environmental factors should be included in economic analytical framework

    Institute of Scientific and Technical Information of China (English)

    金碚

    2009-01-01

    In the economic analysis framework,natural resources and environmental factors are included in the category of capital or land.Hence,the explanatory variables of the production function only include capital,labor and the residue term technology.Such framework may be designed for methodological reasons,but it is determined

  19. Viscoelastic Model of Cross-Linked Polyethylene Including Effects of Temperature and Crystallinity

    Science.gov (United States)

    Olasz, L.; Gudmundson, P.

    2005-12-01

    Characterization of the mechanical behavior of cross-linked polyethylene (XLPE) commonly used in high voltage cable insulation was performed by an extensive set of isothermal uniaxial tensile relaxation tests. Tensile relaxation experiments were complemented by pressure-volume-temperature experiments as well as density and crystallinity measurements. Based on the experimental results, a viscoelastic power law model with four parameters was formulated, incorporating temperature and crystallinity dependence. It was found that a master curve can be developed by both horizontal and vertical shifting of the relaxation curves. The model was evaluated by making comparisons of the predicted stress responses with the measured responses in relaxation tests with transient temperature histories.

  20. Identified Moderate and High Temperature Geothermal Systems of the Western United States including AK and HI

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This layer contains the locations of identified moderate (90 - 150° C) and high (> 150° C) temperature geothermal systems and associated reservoir volumes,...

  1. Efficient air-water heat pumps for high temperature lift residential heating, including oil migration aspects

    OpenAIRE

    Zehnder, Michele; Favrat, Daniel

    2005-01-01

    This thesis presents a system approach with the aim to develop improved concepts for small capacity, high temperature lift air-water heat pumps. These are intended to replace fuel fired heating systems in the residential sector, which leads to a major reduction of the local greenhouse gas emissions. Unfavorable temperature conditions set by the existing heat distribution systems and by the use of atmospheric air, as the only accessible heat source, have to be overcome. The proposed concepts a...

  2. Factors Influencing Temperature Fields during Combustion Reactions

    Science.gov (United States)

    2014-05-20

    PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORTDATE(DD-MM-YYYY) 2. REPORT TYPE 3. DATES COVERED (From - To) New Reprint - 4. TITLE AND...Aluminum Rich Al-Ti Mechanical Alloys in Air, Combust. Flame 2006, 144, 688. [27] Z. Zhang, B. Tsai, G. Machin, Radiometric Temperature Measure- ments

  3. Extension of Lithium Ion Cell Model to Include Transient and Low-Temperature Behaviour

    Science.gov (United States)

    Dudley, G.

    2014-08-01

    Current-interruption resistance measurements have been analysed in detail allowing the ESTEC lithium ion cell electrical/thermal model to be extended to allow modelling of cell voltage in response to imposed current changes at low temperatures and short time scales where activation polarisation becomes important. Whilst an unnecessary complication in most cases, this extension is needed under certain circumstances such as the simulation of Mars rover batteries forced to operate at low temperature and possible effects of battery voltage transients on battery-bus power subsystems. Comparison with test data show that the model is capable of giving a good fit in these circumstances.

  4. Laser diagnostics on atmospheric pressure discharge plasmas, including cryoplasmas, in environments around room and cryogenic temperature

    Science.gov (United States)

    Sakakibara, Noritaka; Muneoka, Hitoshi; Urabe, Keiichiro; Yasui, Ryoma; Sakai, Osamu; Terashima, Kazuo

    2017-04-01

    Cryoplasmas, the plasma gas temperature (T g) of which can be controlled continuously below room temperature, show various unique and advantageous properties depending on T g. Recently, the T g dependence of plasma chemistry related to metastable helium (Hem) has been revealed in helium cryoplasmas. However, T g was only estimated by thermal calculation from the temperature outside the plasmas. In this study, for better evaluation of T g, near-infrared laser heterodyne interferometry (NIR-LHI) measurements were conducted in atmospheric pressure helium pulsed discharge plasmas at around room and cryogenic ambient temperatures (T a). The maximum difference between T g and T a was evaluated as 47 K at T a  =  300 K with 282 mW power consumption. To further investigate the T g dependence of plasma chemical reactions related to Hem, laser absorption spectroscopy (LAS) was performed on the same discharge plasmas to measure the Hem density and lifetime. The Hem lifetime was longer at lower T g, i.e. the lifetime at T g  =  145 K (9.6 µs) was seven times longer than that at T g  =  386 K (1.4 µs). By comparing the results with the numerically simulated rates of Hem quenching reactions taking T g into account, the mechanism of the Hem quenching reaction was revealed to vary with T g even though the main quenching reaction was a three-body collision at all T g. In this manner, the combination of NIR-LHI with LAS led directly to the T g dependence of Hem quenching reactions.

  5. A Study of Factors Promoting Success in Computer Science Including Gender Differences

    Science.gov (United States)

    Cantwell Wilson, Brenda

    2002-03-01

    This study was conducted to determine factors that promote success in an introductory college computer science course and to determine what, if any, differences appear between genders on those factors. The model included math background, attribution for success/failure, self-efficacy, encouragement, comfort level in the course, work style preference, previous programming experience, previous non-programming computer experience, and gender as possible predictive factors for success in the computer science course. Subjects included 105 students enrolled in an introductory computer science course. The study revealed three predictive factors in the following order of importance: comfort level (with a positive influence), math background (with a positive influence), and attribution to luck (with a negative influence). No significant gender differences were found in these three factors. The study also revealed that both a formal class in programming (which had a positive correlation) and game playing (which had a negative correlation) were predictive of success. The study revealed a significant gender difference in game playing with males reporting more experience with playing games on the computer than females reported.

  6. A Note on the Relationship Between Temperature and Water Vapor over Oceans, Including Sea Surface Temperature Effects

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    An ideal and simple formulation is successfully derived that well represents a quasi-linear relationship found between the domain-averaged water vapor, Q (mm), and temperature, T (K), fields for the three tropical oceans (i.e., the Pacific, Atlantic and Indian Oceans) based on eleven GEOS-3 [Goddard Earth Observing System (EOS) Version-3] global re-analysis monthly products. A Q - T distribution analysis is also performed for the tropical and extra-tropical regions based on in-situ sounding data and numerical simulations [GEOS-3 and the Goddard Cumulus Ensemble (GCE) model]. A similar positively correlated Q - T distribution is found over the entire oceanic and tropical regions; however, Q increases faster with T for the former region. It is suspected that the tropical oceans may possess a moister boundary layer than the Tropics. The oceanic regime falls within the lower bound of the tropical regime embedded in a global, curvilinear Q - T relationship. A positive correlation is also found between T and sea surface temperature (SST); however, for one degree of increase in T, SST is found to increase 1.1 degrees for a warmer ocean, which is slightly less than an increase of 1.25 degrees for a colder ocean. This seemingly indicates that more (less) heat is needed for an open ocean to maintain an air mass above it with a same degree of temperature rise during a colder (warmer) season [or in a colder (warmer) region]. Q and SST are also found to be positively correlated. Relative humidity (RH) exhibits similar behaviors for oceanic and tropical regions. RH increases with increasing SST and T over oceans, while it increases with increasing T in the Tropics. RH, however, decreases with increasing temperature in the extratropics. It is suspected that the tropical and oceanic regions may possess a moister local boundary layer than the extratropics so that a faster moisture increase than a saturated moisture increase is favored for the former regions.T, Q, saturated water

  7. TUMOR NECROSIS FACTOR-α INHIBITORS IN THE TREATMENT OF AXIAL SPONDYLOARTHRITIS, INCLUDING ANKYLOSING SPONDYLITIS

    Directory of Open Access Journals (Sweden)

    S. A. Lapshina

    2016-01-01

    Full Text Available The paper provides guidelines for the use of tumor necrosis factor-α  (TNF-α inhibitors in the treatment of patients with axial spondyloarthritis  (axSpA, including ankylosing spondylitis. It gives data on the efficacy of TNF-α inhibitors in patients with non-radiographic axSpA. By using international and Russian guidelines, the authors lay down indications for this therapy and criteria for evaluation of its efficiency and safety.

  8. Z' factor including siRNA design quality parameter in RNAi screening experiments.

    Science.gov (United States)

    Mazur, Sławomir; Kozak, Karol

    2012-05-01

    RNA interference (RNAi) high-content screening (HCS) enables massive parallel gene silencing and is increasingly being used to reveal novel connections between genes and disease-relevant phenotypes. The application of genome-scale RNAi relies on the development of high quality HCS assays. The Z' factor statistic provides a way to evaluate whether or not screening run conditions (reagents, protocols, instrumentation, kinetics, and other conditions not directly related to the test compounds) are optimized. Z' factor, introduced by Zhang et al., ( 1) is a dimensionless value that represents both the variability and the dynamic range between two sets of sample control data. This paper describe a new extension of the Z' factor, which integrates bioinformatics RNAi non-target compounds for screening quality assessment. Currently presented Z' factor is based on positive and negative control, which may not be sufficient for RNAi experiments including oligonucleotides (oligo) with lack of knock-down. This paper proposes an algorithm which extends existing algorithm by using additional controls generetaed from on-target analysis.

  9. Behavioral factors to include in guidelines for lifelong oral healthiness: an observational study in Japanese adults

    Directory of Open Access Journals (Sweden)

    Shimozato Miho

    2006-12-01

    Full Text Available Abstract Background The aim of this study was to determine which behavioral factors to include in guidelines for the Japanese public to achieve an acceptable level of oral healthiness. The objective was to determine the relationship between oral health related behaviors and symptoms related to oral disease and tooth loss in a Japanese adult community. Methods Oral health status and lifestyle were investigated in 777 people aged 20 years and older (390 men and 387 women. Subjects were asked to complete a postal questionnaire concerning past diet and lifestyle. The completed questionnaires were collected when they had health examinations. The 15 questions included their preference for sweets, how many between-meal snacks they usually had per day, smoking and drinking habits, presence of oral symptoms, and attitudes towards dental visits. Participants were asked about their behaviors at different stages of their life. The oral health examinations included examination of the oral cavity and teeth performed by dentists using WHO criteria. Odds ratios were calculated for all subjects, all 10 year age groups, and for subjects 30 years or older, 40 years or older, 50 years or older, and 60 years or older. Results Frequency of tooth brushing (OR = 3.98, having your own toothbrush (OR = 2.11, smoking (OR = 2.71 and bleeding gums (OR = 2.03 were significantly associated with number of retained teeth in males. Frequency of between-meal snacks was strongly associated with number of retained teeth in females (OR = 4.67. Having some hobbies (OR = 2.97, having a family dentist (OR = 2.34 and consulting a dentist as soon as symptoms occurred (OR = 1.74 were significantly associated with number of retained teeth in females. Factors that were significantly associated with tooth loss in both males and females included alcohol consumption (OR = 11.96, males, OR = 3.83, females, swollen gums (OR = 1.93, males, OR = 3.04, females and toothache (OR = 3.39, males, OR

  10. Revised emission factors for gas engines including start/stop emissions

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Malene; Boll Illerup, J.; Birr-Petersen, K.

    2008-06-15

    Liberalisation of the electricity market has led to Danish gas engine plants increasingly converting to the spot and regulating power markets. In order to offer regulating power, plants need to be able to start and stop the engines at the plants quickly. The liberalisation causes a considerable change of operation practice of the engines e.g. less full load operation hours /year. The project provides an inventory determining the scale of the emissions during the start and stop sequence as well as proposals for engine modifications aimed at reducing start/stop emissions. This report includes calculation of emission factors as well as an inventory of total emissions and reduction potentials. (au)

  11. Effects of the Safety Factor on Ion Temperature Gradient Modes

    Institute of Scientific and Technical Information of China (English)

    WANGAike; DONGJiaqi; H.Sanuki; K.Itoh

    2002-01-01

    In the previous models for the ion temperature(ITG)driven instability,the safety factor (r) is introduced into the model through the wavenumber or relative derivative,such sa kθ=lq(r)/r and △1=ik1=(Rq)-1э/эθ.since the safety factor

  12. Pyrometry temperature studies of shocked tin including investigations exploring surface defects, anvil diameter and the integration with emissivity diagnostics

    Science.gov (United States)

    Shenton-Taylor, Caroline; de'Ath, James; Ota, Thomas

    2009-06-01

    Accurate temperature measurement of shock-loaded systems continues to present experimental challenges. With short measurable time durations diagnostic methods are almost exclusively restricted to optical techniques. By preventing full sample pressure unloading, through the use of an anvil, partial release temperature measurements can be deduced from multiple wavelength optical pyrometry. This paper presents our recent studies of tin shocked to 28GPa including investigations exploring surface defects, anvil dimensions and the integration with emissivity diagnostics. The results indicate that a ring groove, 5mm across and with a nominal machined depth of 50 microns, acts to enhance the measured temperature by approximately 150K. Additionally on reducing the LiF anvil diameter from 20mm to 15mm, comparable partial release temperatures were observed. With the anticipated development of multiple anvil target designs, the smaller anvil diameter is desirable. British Crown Copyright 2009/MOD.

  13. An MINLP Model that Includes the Effect of Temperature and Composition on Property Balances for Mass Integration Networks

    Directory of Open Access Journals (Sweden)

    Arturo Jiménez-Gutiérrez

    2014-08-01

    Full Text Available The synthesis of water networks based on properties has commonly ignored the effect of temperature on the property balances that are part of the formulation. When wide differences of temperatures are observed within the process, such an effect might yield significant errors in the application of conventional property balances. In this work, a framework for the development of water networks that include temperature effects on property balances is presented. The approach is based on the inclusion of constants in the property operators that are commonly used to carry out the property balances. An additional term to take care of composition effects is also included. The resulting approach is embedded into a formulation based on a mixed-integer nonlinear programming model for the design of water networks. A case study is presented that shows that the proposed approach yields an improvement in the prediction of the resulting properties for the integrated network, thus affecting the optimal solution.

  14. Prognostic factors of infantile spasms: role of treatment options including a ketogenic diet.

    Science.gov (United States)

    Lee, Jeehun; Lee, Jun Hwa; Yu, Hee Jun; Lee, Munhyang

    2013-09-01

    The aim of this study was to provide additional evidences on prognostic factors for infantile spasms and the possible role of a ketogenic diet. A retrospective analysis was performed for patients with infantile spasms who had been followed up for more than 6months between January 2000 and July 2012 at Samsung Medical Center (Seoul, Republic of Korea). We analyzed the association between possible prognostic factors and seizure/developmental outcomes. Sixty-nine patients were included in this study and their mean follow-up duration was 52.5 (9-147) months. In the patients who had been followed up for more than 2years, 53.6% (n=30/57) remained seizure-free at the last visit. Sixty patients (86.9%) showed developmental delay at last follow-up. Forty-two patients (60.9%) became spasm-free with one or two antiepileptic drugs, one patient with epilepsy surgery for a tumor, and seven patients with a ketogenic diet after the failure of two or more antiepileptic drugs. The etiology and age of seizure onset were the significant prognostic factors. In this study, about 60% of the patients became spasm-free with vigabatrin and topiramate. Ketogenic diet increased the rate by 10% in the remaining antiepileptic drug resistant patients. However, 86.9% of the patients showed developmental delay, mostly a severe degree. Early diagnosis and prompt application of treatment options such as antiepileptic drugs, a ketogenic diet or epilepsy surgery can improve outcomes in patients with infantile spasms. Copyright © 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  15. Macroenvironmental factors including GDP per capita and physical activity in Europe.

    Science.gov (United States)

    Cameron, Adrian J; Van Stralen, Maartje M; Kunst, Anton E; Te Velde, Saskia J; Van Lenthe, Frank J; Salmon, Jo; Brug, Johannes

    2013-02-01

    Socioeconomic inequalities in physical activity at the individual level are well reported. Whether inequalities in economic development and other macroenvironmental variables between countries are also related to physical activity at the country level is comparatively unstudied. We examined the relationship between country-level data on macroenvironmental factors (gross domestic product (GDP) per capita, public sector expenditure on health, percentage living in urban areas, and cars per 1000 population) with country-level physical activity prevalence obtained from previous pan-European studies. Studies that assessed leisuretime physical activity (n = 3 studies including 27 countries in adults, n = 2 studies including 28 countries in children) and total physical activity (n = 3 studies in adults including 16 countries) were analyzed separately as were studies among adults and children. Strong and consistent positive correlations were observed between country prevalence of leisure-time physical activity and country GDP per capita in adults (average r = 0.70; all studies, P G 0.05). In multivariate analysis, country prevalence of leisure-time physical activity among adults remained associated with country GDP per capita (two of three studies) but not urbanization or educational attainment. Among school-age populations, no association was found between country GDP per capita and country prevalence of leisure-time physical activity. In those studies that assessed total physical activity (which also includes occupational and transport physical activity), no association with country GDP per capita was observed. Clear differences in national leisure-time physical activity levels throughout Europe may be a consequence of economic development. Lack of economic development of some countries in Europe may make increasing leisure-time physical activity more difficult. Further examination of the link between country GDP per capita and national physical activity levels (across

  16. Temperature as a proximate factor in orientation behavior

    Energy Technology Data Exchange (ETDEWEB)

    Reynolds, W.W.

    1977-05-01

    Temperature serves as a proximate factor (cue, guidepost, sign stimulus, or directive factor) affecting locomotor responses of fishes. Although temperature can also serve as an ultimate ecological factor, as in behavioral thermoregulation, nonthermal factors may in some cases provide the ultimate adaptive or ecological value of a temperature response; some examples are habitat selection, intraspecific size segregation, interspecific niche differentiation, isolating mechanisms, predator avoidance, prey location, escape reactions, and migrations (thermoperiodic, diel, seasonal, spawning). Conversely, nonthermal variables such as light intensity or water depth may act as accessory proximate factors in thermoregulation. In spawning migrations, thermal requirements of eggs and larvae may take precedence over the (often different) preferenda or optima of adults. Although thermal responses of fishes are largely innate and species specific, ontogenetic and other changes can occur. Since temperature can serve as an unconditioned reinforcer in operant conditioning, thermal responses are not limited to simple kineses or taxes. Nonthermal factors such as photoperiod, circadian rhythms, currents, social and biotic interactions, stresses, infections, or chemicals can affect thermal responses, and may account for some lack of conformity between laboratory preferenda and field distributions and behaviors.

  17. Calibration of Gyros with Temperature Dependent Scale Factors

    Science.gov (United States)

    Belur, Sheela V.; Harman, Richard

    2001-01-01

    The general problem of gyro calibration can be stated as the estimation of the scale factors, misalignments, and drift-rate biases of the gyro using the on-orbit sensor measurements. These gyro parameters have been traditionally treated as temperature-independent in the operational flight dynamics ground systems at NASA Goddard Space Flight Center (GSFC), a scenario which has been successfully applied in the gyro calibration of a large number of missions. A significant departure from this is the Microwave Anisotropy Probe (MAP) mission where, due to the high thermal variations expected during the mission phase, it is necessary to model the scale factors as functions of temperature. This paper addresses the issue of gyro calibration for the MAP gyro model using a manufacturer-supplied model of the variation of scale factors with temperature. The problem is formulated as a least squares problem and solved using the Levenberg-Marquardt algorithm in the MATLAB(R) library function NLSQ. The algorithm was tested on simulated data with Gaussian noise for the quaternions as well as the gyro rates and was found to consistently converge close to the true values. Significant improvement in accuracy was noticed due to the estimation of the temperature-dependent scale factors as against constant scale factors.

  18. Health Promotion Behavior of Chinese International Students in Korea Including Acculturation Factors: A Structural Equation Model.

    Science.gov (United States)

    Kim, Sun Jung; Yoo, Il Young

    2016-03-01

    The purpose of this study was to explain the health promotion behavior of Chinese international students in Korea using a structural equation model including acculturation factors. A survey using self-administered questionnaires was employed. Data were collected from 272 Chinese students who have resided in Korea for longer than 6 months. The data were analyzed using structural equation modeling. The p value of final model is .31. The fitness parameters of the final model such as goodness of fit index, adjusted goodness of fit index, normed fit index, non-normed fit index, and comparative fit index were more than .95. Root mean square of residual and root mean square error of approximation also met the criteria. Self-esteem, perceived health status, acculturative stress and acculturation level had direct effects on health promotion behavior of the participants and the model explained 30.0% of variance. The Chinese students in Korea with higher self-esteem, perceived health status, acculturation level, and lower acculturative stress reported higher health promotion behavior. The findings can be applied to develop health promotion strategies for this population. Copyright © 2016. Published by Elsevier B.V.

  19. Temperature can interact with landscape factors to affect songbird productivity.

    Science.gov (United States)

    Cox, W Andrew; Thompson, Frank R; Reidy, Jennifer L; Faaborg, John

    2013-04-01

    Increased temperatures and more extreme weather patterns associated with global climate change can interact with other factors that regulate animal populations, but many climate change studies do not incorporate other threats to wildlife in their analyses. We used 20 years of nest-monitoring data from study sites across a gradient of habitat fragmentation in Missouri, USA, to investigate the relative influence of weather variables (temperature and precipitation) and landscape factors (forest cover and edge density) on the number of young produced per nest attempt (i.e., productivity) for three species of songbirds. We detected a strong forest cover × temperature interaction for the Acadian Flycatcher (Empidonax virescens) on productivity. Greater forest cover resulted in greater productivity because of reduced brood parasitism and increased nest survival, whereas greater temperatures reduced productivity in highly forested landscapes because of increased nest predation but had no effect in less forested landscapes. The Indigo Bunting (Passerina cyanea) exhibited a similar pattern, albeit with a marginal forest cover × temperature interaction. By contrast, productivity of the Northern Cardinal (Cardinalis cardinalis) was not influenced by landscape effects or temperature. Our results highlight a potential difficulty of managing wildlife in response to global change such as habitat fragmentation and climate warming, as the habitat associated with the greatest productivity for flycatchers was also that most negatively influenced by high temperatures. The influence of high temperatures on nest predation (and therefore, nest predators) underscores the need to acknowledge the potential complexity of species' responses to climate change by incorporating a more thorough consideration of community ecology in the development of models of climate impacts on wildlife.

  20. Factorization of Radiative Leptonic Decays of $B^-$ and $D^-$ Mesons Including the Soft Photon Region

    CERN Document Server

    Yang, Ji-Chong

    2016-01-01

    In this work, we study the radiative leptonic decays of $B^-$ and $D^-$ mesons using factorization approach. Factorization is proved to be valid explicitly at 1-loop level at any order of $O(\\Lambda _{\\rm QCD}\\left/m_Q\\right.)$. We consider the contribution in the soft photon region that $E_{\\gamma} \\sim \\left. \\Lambda^2 _{\\rm QCD} /\\right. m_Q$. The numerical results shows that, the soft photon region is very important for both the $B$ and $D$ mesons. The branching ratios of $B\\to \\gamma e\

  1. Recent Progress on Labfit: a Multispectrum Analysis Program for Fitting Lineshapes Including the Htp Model and Temperature Dependence

    Science.gov (United States)

    Cich, Matthew J.; Guillaume, Alexandre; Drouin, Brian; Benner, D. Chris

    2017-06-01

    Multispectrum analysis can be a challenge for a variety of reasons. It can be computationally intensive to fit a proper line shape model especially for high resolution experimental data. Band-wide analyses including many transitions along with interactions, across many pressures and temperatures are essential to accurately model, for example, atmospherically relevant systems. Labfit is a fast multispectrum analysis program originally developed by D. Chris Benner with a text-based interface. More recently at JPL a graphical user interface was developed with the goal of increasing the ease of use but also the number of potential users. The HTP lineshape model has been added to Labfit keeping it up-to-date with community standards. Recent analyses using labfit will be shown to demonstrate its ability to competently handle large experimental datasets, including high order lineshape effects, that are otherwise unmanageable.

  2. Situational effects of the school factors included in the dynamic model of educational effectiveness

    NARCIS (Netherlands)

    Creerners, Bert; Kyriakides, Leonidas

    2009-01-01

    We present results of a longitudinal study in which 50 schools, 113 classes and 2,542 Cypriot primary students participated. We tested the validity of the dynamic model of educational effectiveness and especially its assumption that the impact of school factors depends on the current situation of th

  3. Latina Resilience in Higher Education: Contributing Factors Including Seasonal Farmworker Experiences

    Science.gov (United States)

    Graff, Cristina Santamaria; McCain, Terrence; Gomez-Vilchis, Veronica

    2013-01-01

    Many Latina students overcome multiple obstacles to earn university degrees. Five married Latina women with children and seasonal farmworker backgrounds are the focus of this study which is analyzed through resiliency theory to understand factors contributing to their academic resilience. Variables connected to academic success are explored and…

  4. Simultaneous Spectrophotometric Determination of Four Components including Acetaminophen by Taget Factor Analysis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    UV Spectrophotometric Target Factor Analysis (TFA) was used for the simultaneous determination of four components (acetaminophen, guuaifenesin, caffeine, Chlorphenamine maleate) in cough syrup. The computer program of TFA is based on VC++ language. The difficulty of overlapping of absorption spectra of four compounds was overcome by this procedure. The experimental results show that the average recovery of each component is all in the range from 98.9% to 106.8% and each component obtains satisfactory results without any pre-separation.

  5. The N(H2/I(CO Conversion Factor: A Treatment that Includes Radiative Transfer

    Directory of Open Access Journals (Sweden)

    W. F. Wall

    2006-01-01

    Full Text Available Se presenta un tratamiento que explica mejor el factor de conversión N(H2=I(CO y que incluye la transferencia radiativa. A primera vista, incluir la transferencia radiativa parece superfluo para una línea óptimamente gruesa como CO J = 1 0. No obstante, dado que el medio interestelar es inhomogéneo, los fragmentos de gas (es decir, grumos todavía pueden ser óptimamente delgadas hacia sus bordes y en las alas de los pérfiles de la línea. El tratamiento estadístico de Martin et al. (1984 de la transferencia radiativa a través una nube molecular con grumos se usa para derivar una expresión para el factor de conversión que su- pera los defectos de las explicaciones más tradicionales basadas en Dickman et al. (1986. Por un lado, el tratamiento presentado aquí posiblemente representa un avance importante al entender el factor de conversión N(H2=I(CO pero, por otro lado, tiene sus propios defectos, que son discutidos aquí brevemente.

  6. Preoperative Serum Interleukin-6 Is a Potential Prognostic Factor for Colorectal Cancer, including Stage II Patients

    Directory of Open Access Journals (Sweden)

    Kazuyoshi Shiga

    2016-01-01

    Full Text Available Aims. To evaluate the prognostic significance of serum interleukin-6 (IL-6 in colorectal cancer (CRC. Patients and Methods. Preoperative serum IL-6 was measured in 233 CRC patients and 13 healthy controls. Relationships between IL-6 and various clinicopathological factors were evaluated, and the overall survival (OS and disease-free survival (DFS rates according to IL-6 status were calculated for all patients and according to disease stage. Results. The mean IL-6 level was 6.6 pg/mL in CRC patients and 2.6 pg/mL in healthy controls. Using a cutoff of 6.3 pg/mL, obtained using receiver operating characteristic curve analysis, 57 patients had a high IL-6 level. The mean value was higher for stage II disease than for stage III disease. IL-6 status correlated with C-reactive protein (CRP and carcinoembryonic antigen levels, obstruction, and pT4 disease. The OS differed according to the IL-6 status for all patients, whereas the DFS differed for all patients and for those with stage II disease. The Cox proportional hazards model showed that pT4 disease was an independent risk factor for recurrence in all CRC patients; IL-6, CRP, and pT4 were significant risk factors in stage II patients. Conclusions. The preoperative IL-6 level influences the risk of CRC recurrence.

  7. Current Changes in Pubertal Timing: Revised Vision in Relation with Environmental Factors Including Endocrine Disruptors.

    Science.gov (United States)

    Parent, Anne-Simone; Franssen, Delphine; Fudvoye, Julie; Pinson, Anneline; Bourguignon, Jean-Pierre

    2016-01-01

    The aim of this chapter is to revise some common views on changes in pubertal timing. This revision is based on recent epidemiological findings on the clinical indicators of pubertal timing and data on environmental factor effects and underlying mechanisms. A current advancement in timing of female puberty is usually emphasized. It appears, however, that timing is also changing in males. Moreover, the changes are towards earliness for initial pubertal stages and towards lateness for final stages in both sexes. Such observations indicate the complexity of environmental influences on pubertal timing. The mechanisms of changes in pubertal timing may involve both the central neuroendocrine control and peripheral effects at tissues targeted by gonadal steroids. While sufficient energy availability is a clue to the mechanism of pubertal development, changes in the control of both energy balance and reproduction may vary under the influence of common determinants such as endocrine-disrupting chemicals (EDCs). These effects can take place right before puberty as well as much earlier, during fetal and neonatal life. Finally, environmental factors can interact with genetic factors in determining changes in pubertal timing. Therefore, the variance in pubertal timing is no longer to be considered under absolutely separate control by environmental and genetic determinants. Some recommendations are provided for evaluation of EDC impact in the management of pubertal disorders and for possible reduction of EDC exposure along the precautionary principle.

  8. Nuclear monopole charge form factor calculation for relativistic models including center-of-mass corrections

    Energy Technology Data Exchange (ETDEWEB)

    Avancini, S.S.; Marinelli, J.R. [Universidade Federal de Santa Catarina Florianopolis, Depto de Fisica - CFM, Florianopolis (Brazil); Carlson, B.V. [Instituto Tecnologico de Aeronautica, Sao Jose dos Campos (Brazil)

    2013-06-15

    Relativistic models for finite nuclei contain spurious center-of-mass motion in most applications for the nuclear many-body problem, where the nuclear wave function is taken as a single Slater determinant within a space-fixed frame description. We use the Peierls-Yoccoz projection method, previously developed for relativistic approaches together with a reparametrization of the coupling constants that fits binding energies and charge radius and apply our results to calculate elastic electron scattering monopole charge form factors for light nuclei. (orig.)

  9. SUBSTANTIATION OF THE COST OF HOUSING CONSTRUCTION INCLUDING THE FACTOR OF INVESTMENT ATTRACTIVENESS OF TERRITORIES

    Directory of Open Access Journals (Sweden)

    ZAIATS Yi. I.

    2015-11-01

    Full Text Available Problem statement. For planning and organization of urban construction is necessary to analyze the use of areas. Territorial resources of the city, being used for construction and other urban purposes, consists of plots of land: disposable, reserved and undeveloped in previous years of construction in progress; residential districts and blocks of obsolete housing fund; industrial and municipal and warehouse enterprises being used irrationally or stopped to work; the defence department, where the amortized warehouses and other main funds are that are not used by purpose; agricultural enterprises where the obsolete industrial funds, haying, nurseries, greenhouses. The number of free areas suitable for future urban development is extremely limited. However a considerable part of the territories of almost all functional zones is used inefficiently. Purpose. Formalization of a factor of investment attractiveness of territories for the further identification and research of the connection between it and the cost of housing construction is necessary. Conclusion. The identification of regularities of influence of the factor of investment attractiveness of territories on the cost of construction of high-rise buildings allow to obtain a quantitative estimate of this effect and can be used in the development of the methodology of substantiation of the expediency and effectiveness of the implementation of highrise construction projects, based on organizational and technological aspects.

  10. Modelling of safety barriers including human and organisational factors to improve process safety

    DEFF Research Database (Denmark)

    Markert, Frank; Duijm, Nijs Jan; Thommesen, Jacob

    2013-01-01

    explosion, and the Mont Blanc Tunnel Fire, such an approach may have helped to maintain the integrity of the designed provisions against major deviations resulting in these disasters. In order to make this paradigm operational, safety management and in particular risk assessment tools need to be refined....... A valuable approach is the inclusion of human and organisational factors into the simulation of the reliability of the technical system using event trees and fault trees and the concept of safety barriers. This has been demonstrated e.g. in the former European research project ARAMIS (Accidental Risk...... Assessment Methodology for IndustrieS, see Salvi et al 2006). ARAMIS employs the bow-tie approach to modelling hazardous scenarios, and it suggests the outcome of auditing safety management to be connected to a semi-quantitative assessment of the quality of safety barriers. ARAMIS discriminates a number...

  11. Contribution of Environmental Risk Factors Including Lifestyle to Inequalities Noncommunicable (Chronic Diseases such as Diabetes

    Directory of Open Access Journals (Sweden)

    Elzbieta Grochowska Niedworok

    2015-06-01

    Full Text Available Health inequalities: differences in health status or in the distribution of health determinants between different population groups. Some health inequalities are attributable to biological variations or free choice and others are attributable to the external environment and conditions mainly outside the control of the individuals concerned. 347 million people worldwide have diabetes. In 2012 an estimated 1.5 million deaths were directly caused by diabetes. More than 80% of diabetes deaths occur in low- and middle-income countries. WHO projects that diabetes will be the 7th leading cause of death in 2030. Healthy diet, regular physical activity and maintaining a normal body weight can prevent or delay the onset of type 2 diabetes. Risk factors: 1. Age- the prevalence of diabetes rises steeply with age: *one in twenty people over the age of 65 have diabetes, *and this rises to one in five people over the age of 85 years. The diagnosis of diabetes may be delayed in older people, with symptoms of diabetes being wrongly attributed to ageing. 2. Ethnic: type 2 diabetes is up to six times more common in people of South Asian descent and up to three times more common in those of African and African-Caribbean descent then in the white population. It is also more common in people of Chinese descent and other non-Caucasian groups. 3. Gender: the frequency of diabetes usually is higher in men than in women. This may be because gender compounds other aspects of inequality- women often bear the brunt of poverty, and socio-economic differences in the prevalence of diabetes are more marked for women, probably because of differences in smoking rates, food choices and the prevalence of obesity. 4. Overweight/Obesity: every 1 kg/m2 more causes increase risk: cardiovascular diseases 2%, coronary artery disease- 3% , myocardial infarction- 5% , heart failure- 5% , peripheral vascular disease- 5%. Health inqualities important in diabetes -- modifiable:  social

  12. Multiphase Binary Mixture Flows in Porous Media in a Wide Pressure and Temperature Range Including Critical Conditions

    Science.gov (United States)

    Afanasyev, A.

    2011-12-01

    Multiphase flows in porous media with a transition between sub- and supercritical thermodynamic conditions occur in many natural and technological processes (e.g. in deep regions of geothermal reservoirs where temperature reaches critical point of water or in gas-condensate fields where subject to critical conditions retrograde condensation occurs and even in underground carbon dioxide sequestration processes at high formation pressure). Simulation of these processes is complicated due to degeneration of conservation laws under critical conditions and requires non-classical mathematical models and methods. A new mathematical model is proposed for efficient simulation of binary mixture flows in a wide range of pressures and temperatures that includes critical conditions. The distinctive feature of the model lies in the methodology for mixture properties determination. Transport equations and Darcy law are solved together with calculation of the entropy maximum that is reached in thermodynamic equilibrium and determines mixture composition. To define and solve the problem only one function - mixture thermodynamic potential - is required. Such approach allows determination not only single-phase states and two-phase states of liquid-gas type as in classical models but also two-phase states of liquid-liquid type and three-phase states. The proposed mixture model was implemented in MUFITS (Multiphase Filtration Transport Simulator) code for hydrodynamic simulations. As opposed to classical approaches pressure, enthalpy and composition variables together with fully implicit method and cascade procedure are used. The code is capable of unstructured grids, heterogeneous porous media, relative permeability and capillary pressure dependence on temperature and pressure, multiphase diffusion, optional number of sink and sources, etc. There is an additional module for mixture properties specification. The starting point for the simulation is a cubic equation of state that is

  13. Finite volume form factors and correlation functions at finite temperature

    CERN Document Server

    Pozsgay, Balázs

    2009-01-01

    In this thesis we investigate finite size effects in 1+1 dimensional integrable QFT. In particular we consider matrix elements of local operators (finite volume form factors) and vacuum expectation values and correlation functions at finite temperature. In the first part of the thesis we give a complete description of the finite volume form factors in terms of the infinite volume form factors (solutions of the bootstrap program) and the S-matrix of the theory. The calculations are correct to all orders in the inverse of the volume, only exponentially decaying (residual) finite size effects are neglected. We also consider matrix elements with disconnected pieces and determine the general rule for evaluating such contributions in a finite volume. The analytic results are tested against numerical data obtained by the truncated conformal space approach in the Lee-Yang model and the Ising model in a magnetic field. In a separate section we also evaluate the leading exponential correction (the $\\mu$-term) associate...

  14. Factors affecting characterization of bulk high-temperature superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Hull, J.R. [Argonne National Lab., IL (United States). Energy Technology Div.

    1997-11-01

    Three major factors affect the characterization of bulk high-temperature superconductors in terms of their levitation properties during interaction with permanent magnets. First, the appropriate parameter for the permanent magnet is internal magnetization, not the value of the magnetic field measured at the magnet`s surface. Second, although levitation force grows with superconductor thickness and surface area, for a given permanent magnet size, comparison of levitation force between samples is meaningful when minimum values are assigned to the superconductor size parameters. Finally, the effect of force creep must be considered when time-averaging the force measurements. In addition to levitational force, the coefficient of friction of a levitated rotating permanent magnet may be used to characterize the superconductor.

  15. Factors contributing to the temperature beneath plaster or fiberglass cast material

    Science.gov (United States)

    Hutchinson, Michael J; Hutchinson, Mark R

    2008-01-01

    Background Most cast materials mature and harden via an exothermic reaction. Although rare, thermal injuries secondary to casting can occur. The purpose of this study was to evaluate factors that contribute to the elevated temperature beneath a cast and, more specifically, evaluate the differences of modern casting materials including fiberglass and prefabricated splints. Methods The temperature beneath various types (plaster, fiberglass, and fiberglass splints), brands, and thickness of cast material were measured after they were applied over thermometer which was on the surface of a single diameter and thickness PVC tube. A single layer of cotton stockinette with variable layers and types of cast padding were placed prior to application of the cast. Serial temperature measurements were made as the cast matured and reached peak temperature. Time to peak, duration of peak, and peak temperature were noted. Additional tests included varying the dip water temperature and assessing external insulating factors. Ambient temperature, ambient humidity and dip water freshness were controlled. Results Outcomes revealed that material type, cast thickness, and dip water temperature played key roles regarding the temperature beneath the cast. Faster setting plasters achieved peak temperature quicker and at a higher level than slower setting plasters. Thicker fiberglass and plaster casts led to greater peak temperature levels. Likewise increasing dip-water temperature led to elevated temperatures. The thickness and type of cast padding had less of an effect for all materials. With a definition of thermal injury risk of skin injury being greater than 49 degrees Celsius, we found that thick casts of extra fast setting plaster consistently approached dangerous levels (greater than 49 degrees for an extended period). Indeed a cast of extra-fast setting plaster, 20 layers thick, placed on a pillow during maturation maintained temperatures over 50 degrees of Celsius for over 20

  16. Factors contributing to the temperature beneath plaster or fiberglass cast material

    Directory of Open Access Journals (Sweden)

    Hutchinson Mark R

    2008-02-01

    Full Text Available Abstract Background Most cast materials mature and harden via an exothermic reaction. Although rare, thermal injuries secondary to casting can occur. The purpose of this study was to evaluate factors that contribute to the elevated temperature beneath a cast and, more specifically, evaluate the differences of modern casting materials including fiberglass and prefabricated splints. Methods The temperature beneath various types (plaster, fiberglass, and fiberglass splints, brands, and thickness of cast material were measured after they were applied over thermometer which was on the surface of a single diameter and thickness PVC tube. A single layer of cotton stockinette with variable layers and types of cast padding were placed prior to application of the cast. Serial temperature measurements were made as the cast matured and reached peak temperature. Time to peak, duration of peak, and peak temperature were noted. Additional tests included varying the dip water temperature and assessing external insulating factors. Ambient temperature, ambient humidity and dip water freshness were controlled. Results Outcomes revealed that material type, cast thickness, and dip water temperature played key roles regarding the temperature beneath the cast. Faster setting plasters achieved peak temperature quicker and at a higher level than slower setting plasters. Thicker fiberglass and plaster casts led to greater peak temperature levels. Likewise increasing dip-water temperature led to elevated temperatures. The thickness and type of cast padding had less of an effect for all materials. With a definition of thermal injury risk of skin injury being greater than 49 degrees Celsius, we found that thick casts of extra fast setting plaster consistently approached dangerous levels (greater than 49 degrees for an extended period. Indeed a cast of extra-fast setting plaster, 20 layers thick, placed on a pillow during maturation maintained temperatures over 50 degrees of

  17. Contribution of thermal and nonthermal factors to the regulation of body temperature in humans

    National Research Council Canada - National Science Library

    Igor B. Mekjavic; Ola Eiken

    2006-01-01

    .... This reciprocal inhibition theory, presumably reflecting the manner in which thermal factors contribute to homeothermy in humans, does not incorporate the effect of nonthermal factors on temperature regulation...

  18. Impact of Outliers Arising from Unintended and Unknowingly Included Subpopulations on the Decisions about the Number of Factors in Exploratory Factor Analysis

    Science.gov (United States)

    Liu, Yan; Zumbo, Bruno D.

    2012-01-01

    There is a lack of research on the effects of outliers on the decisions about the number of factors to retain in an exploratory factor analysis, especially for outliers arising from unintended and unknowingly included subpopulations. The purpose of the present research was to investigate how outliers from an unintended and unknowingly included…

  19. A New Method to Measure Temperature and Burner Pattern Factor Sensing for Active Engine Control

    Science.gov (United States)

    Ng, Daniel

    1999-01-01

    The determination of the temperatures of extended surfaces which exhibit non-uniform temperature variation is very important for a number of applications including the "Burner Pattern Factor" (BPF) of turbine engines. Exploratory work has shown that use of BPF to control engine functions can result in many benefits, among them reduction in engine weight, reduction in operating cost, increase in engine life, while attaining maximum engine efficiency. Advanced engines are expected to operate at very high temperature to achieve high efficiency. Brief exposure of engine components to higher than design temperatures due to non-uniformity in engine burner pattern can reduce engine life. The engine BPF is a measure of engine temperature uniformity. Attainment of maximum temperature uniformity and high temperatures is key to maximum efficiency and long life. A new approach to determine through the measurement of just one radiation spectrum by a multiwavelength pyrometer is possible. This paper discusses a new temperature sensing approach and its application to determine the BPF.

  20. 49 CFR 192.115 - Temperature derating factor (T) for steel pipe.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Temperature derating factor (T) for steel pipe... SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Pipe Design § 192.115 Temperature derating factor (T) for steel pipe. The temperature derating factor to be used in...

  1. The Benefits of Including Clinical Factors in Rectal Normal Tissue Complication Probability Modeling After Radiotherapy for Prostate Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Defraene, Gilles, E-mail: gilles.defraene@uzleuven.be [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Van den Bergh, Laura [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Al-Mamgani, Abrahim [Department of Radiation Oncology, Erasmus Medical Center - Daniel den Hoed Cancer Center, Rotterdam (Netherlands); Haustermans, Karin [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Heemsbergen, Wilma [Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam (Netherlands); Van den Heuvel, Frank [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Lebesque, Joos V. [Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam (Netherlands)

    2012-03-01

    Purpose: To study the impact of clinical predisposing factors on rectal normal tissue complication probability modeling using the updated results of the Dutch prostate dose-escalation trial. Methods and Materials: Toxicity data of 512 patients (conformally treated to 68 Gy [n = 284] and 78 Gy [n = 228]) with complete follow-up at 3 years after radiotherapy were studied. Scored end points were rectal bleeding, high stool frequency, and fecal incontinence. Two traditional dose-based models (Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) and a logistic model were fitted using a maximum likelihood approach. Furthermore, these model fits were improved by including the most significant clinical factors. The area under the receiver operating characteristic curve (AUC) was used to compare the discriminating ability of all fits. Results: Including clinical factors significantly increased the predictive power of the models for all end points. In the optimal LKB, RS, and logistic models for rectal bleeding and fecal incontinence, the first significant (p = 0.011-0.013) clinical factor was 'previous abdominal surgery.' As second significant (p = 0.012-0.016) factor, 'cardiac history' was included in all three rectal bleeding fits, whereas including 'diabetes' was significant (p = 0.039-0.048) in fecal incontinence modeling but only in the LKB and logistic models. High stool frequency fits only benefitted significantly (p = 0.003-0.006) from the inclusion of the baseline toxicity score. For all models rectal bleeding fits had the highest AUC (0.77) where it was 0.63 and 0.68 for high stool frequency and fecal incontinence, respectively. LKB and logistic model fits resulted in similar values for the volume parameter. The steepness parameter was somewhat higher in the logistic model, also resulting in a slightly lower D{sub 50}. Anal wall DVHs were used for fecal incontinence, whereas anorectal wall dose best described the other two endpoints

  2. Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes

    Science.gov (United States)

    Nagaishi, Kanna; Mizue, Yuka; Chikenji, Takako; Otani, Miho; Nakano, Masako; Konari, Naoto; Fujimiya, Mineko

    2016-01-01

    Bone marrow-derived mesenchymal stem cells (MSCs) have contributed to the improvement of diabetic nephropathy (DN); however, the actual mediator of this effect and its role has not been characterized thoroughly. We investigated the effects of MSC therapy on DN, focusing on the paracrine effect of renal trophic factors, including exosomes secreted by MSCs. MSCs and MSC-conditioned medium (MSC-CM) as renal trophic factors were administered in parallel to high-fat diet (HFD)-induced type 2 diabetic mice and streptozotocin (STZ)-induced insulin-deficient diabetic mice. Both therapies showed approximately equivalent curative effects, as each inhibited the exacerbation of albuminuria. They also suppressed the excessive infiltration of BMDCs into the kidney by regulating the expression of the adhesion molecule ICAM-1. Proinflammatory cytokine expression (e.g., TNF-α) and fibrosis in tubular interstitium were inhibited. TGF-β1 expression was down-regulated and tight junction protein expression (e.g., ZO-1) was maintained, which sequentially suppressed the epithelial-to-mesenchymal transition of tubular epithelial cells (TECs). Exosomes purified from MSC-CM exerted an anti-apoptotic effect and protected tight junction structure in TECs. The increase of glomerular mesangium substrate was inhibited in HFD-diabetic mice. MSC therapy is a promising tool to prevent DN via the paracrine effect of renal trophic factors including exosomes due to its multifactorial action. PMID:27721418

  3. Urban heat : natural and anthropogenic factors influencing urban air temperatures

    NARCIS (Netherlands)

    Theeuwes, N.E.

    2015-01-01

    The urban heat island effect is a phenomenon observed worldwide, i.e. evening and nocturnal temperatures in cities are usually several degrees higher than in the surrounding countryside. The main goal of this thesis is to understand the processes that drive the urban air temperature and the urban he

  4. Hysteresis in Lanthanide Zirconium Oxides Observed Using a Pulse CV Technique and including the Effect of High Temperature Annealing

    Directory of Open Access Journals (Sweden)

    Qifeng Lu

    2015-07-01

    Full Text Available A powerful characterization technique, pulse capacitance-voltage (CV technique, was used to investigate oxide traps before and after annealing for lanthanide zirconium oxide thin films deposited on n-type Si (111 substrates at 300 °C by liquid injection Atomic Layer Deposition (ALD. The results indicated that: (1 more traps were observed compared to the conventional capacitance-voltage characterization method in LaZrOx; (2 the time-dependent trapping/de-trapping was influenced by the edge time, width and peak-to-peak voltage of a gate voltage pulse. Post deposition annealing was performed at 700 °C, 800 °C and 900 °C in N2 ambient for 15 s to the samples with 200 ALD cycles. The effect of the high temperature annealing on oxide traps and leakage current were subsequently explored. It showed that more traps were generated after annealing with the trap density increasing from 1.41 × 1012 cm−2 for as-deposited sample to 4.55 × 1012 cm−2 for the 800 °C annealed one. In addition, the leakage current density increase from about 10−6 A/cm2 at Vg = +0.5 V for the as-deposited sample to 10−3 A/cm2 at Vg = +0.5 V for the 900 °C annealed one.

  5. Analysis of Factors That Affects the Capital Structure within Companies Included In the Index of LQ45 During 2011 - 2013

    Directory of Open Access Journals (Sweden)

    Dominica Rufina

    2016-01-01

    Full Text Available This study aims to determine the factors of ROA, Asset Structure, Sales Growth, and Firm Size affecting Capital Structure. The population in this study is the companies included in the Index LQ45 Indonesia Stock Exchange from the period 2011 to 2013, the data of a total of 270 listed companies in LQ45 during that period, only 90 corporate data that successively included in the index LQ45. The data used in this study uses secondary data from the Indonesia Stock Exchange website www.idx.co.id. In the process of data analysis and testing the assumptions of classical hypothesis testing using multiple linear regression analysis using SPSS v20.00. The results showed that partially variable ROA, Asset Structure, and Firm Size has a significant influence on the Capital Structure, Growth Sales whereas variable has no influence on the Capital Structure. Simultaneously ROA, Asset Structure, Sales Growth, and Firm Size effect on Capital Structure.

  6. Basic factors controlling pest in high temperature systems

    Science.gov (United States)

    Berkowitz-Mattuck, J.; Rossetti, M.

    1971-01-01

    The catastrophic disintegration in air at intermediate temperatures of refractory materials which are very resistant to oxidation at high temperatures is known as pest. A study was undertaken to determine whether the mechanism proposed for pest failure in silicides might also be responsible for pest failure in NbAl3. The aim was to correlate oxidation kinetics in the range where disintegration of NbAl3 is observed with delayed failure data obtained under similar conditions. Studies were also undertaken to develop some understanding of deformation mechanisms in both silicides and aluminides.

  7. A new prognostic model for cancer-specific survival after radical cystectomy including pretreatment thrombocytosis and standard pathological risk factors.

    Science.gov (United States)

    Todenhöfer, Tilman; Renninger, Markus; Schwentner, Christian; Stenzl, Arnulf; Gakis, Georgios

    2012-12-01

    Study Type - Prognosis (cohort series) Level of Evidence 2a What's known on the subject? and What does the study add? Preoperative thrombocytosis has been identified as a predictor of poor outcome in various cancer types. However, the prognostic role of platelet count in patients with invasive bladder cancer undergoing radical cystectomy is unknown. The present study demonstrates that preoperative thrombocytosis is an independent risk factor for decreased cancer-specific survival after radical treatment of invasive bladder cancer. We developed a new prognostic scoring model for cancer-specific outcomes after radical cystectomy including platelet count and established pathological risk factors. Consideration of platelet count in the final model increased its predictive accuracy significantly. Thrombocytosis may be a useful parameter to include within established international bladder cancer nomograms. •  To investigate the oncological significance of preoperative thrombocytosis in patients with invasive bladder cancer undergoing radical cystectomy, as it has been reported as a marker for aggressive tumour biology in a variety of solid tumours. •  The series comprised 258 patients undergoing radical cystectomy between 1999 and 2010 in whom different clinical and histopathological parameters were assessed. •  Elevated platelet count was defined as >450 × 10(9) /L. •  Based on regression estimates of significant parameters in multivariable analysis a new weighted scoring model was developed to predict cancer-specific outcomes. •  The median follow-up was 30 months (6-116). •  Of the 258 patients, 26 (10.1%) had elevated and 232 (89.9%) had normal platelet count. The 3-year cancer-specific survival in patients with normal and elevated platelet count was 61.5% and 32.7%, respectively (P thrombocytosis (2.68, 1.26-5.14; P= 0.011). •  The 3-year cancer-specific survival in patients with a score 0 (low risk), 1-2 (intermediate risk) and 3

  8. Comments on "Including the effects of temperature-dependent opacities in the implicit Monte Carlo algorithm" by N.A. Gentile [J. Comput. Phys. 230 (2011) 5100-5114

    Science.gov (United States)

    Ghosh, Karabi

    2017-02-01

    We briefly comment on a paper by N.A. Gentile [J. Comput. Phys. 230 (2011) 5100-5114] in which the Fleck factor has been modified to include the effects of temperature-dependent opacities in the implicit Monte Carlo algorithm developed by Fleck and Cummings [1,2]. Instead of the Fleck factor, f = 1 / (1 + βcΔtσP), the author derived the modified Fleck factor g = 1 / (1 + βcΔtσP - min [σP‧ (a Tr4 - aT4) cΔt/ρCV, 0 ]) to be used in the Implicit Monte Carlo (IMC) algorithm in order to obtain more accurate solutions with much larger time steps. Here β = 4 aT3 / ρCV, σP is the Planck opacity and the derivative of Planck opacity w.r.t. the material temperature is σP‧ = dσP / dT.

  9. Relative Damage Stress: Dominant Mechanical Factor for the Failure of Soldered Joints under Temperature Cycling

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    By temperature normalization of the concept of equivalent damage stress proposed by Lemaitre,a new concept of relative damage stress has been put forward as the dominant mechanical factor for the failure of soldered joints under temperature cycling. Finite element numerical simulation results showed that the highest value of relative damage stress occurred at the high temperaturehold time during temperature cycling history.

  10. Factors that influence effective perioperative temperature management by anesthesiologists: a qualitative study using the Theoretical Domains Framework.

    Science.gov (United States)

    Boet, Sylvain; Patey, Andrea M; Baron, Justine S; Mohamed, Karim; Pigford, Ashlee-Ann E; Bryson, Gregory L; Brehaut, Jamie C; Grimshaw, Jeremy M

    2017-06-01

    Inadvertent perioperative hypothermia (IPH) is associated with a range of adverse outcomes. Safe and effective warming techniques exist to prevent IPH; however, IPH remains common. This study aimed to identify factors that anesthesiologists perceive may influence temperature management during the perioperative period. After Research Ethics Board approval, semi-structured interviews were conducted with staff anesthesiologists at a Canadian academic hospital. An interview guide based on the Theoretical Domains Framework (TDF) was used to capture 14 theoretical domains that may influence temperature management. The interview transcripts were coded using direct content analysis to generate specific beliefs and to identify relevant TDF domains perceived to influence temperature management behaviour. Data saturation was achieved after 15 interviews. The following nine theoretical domains were identified as relevant to designing an intervention for practices in perioperative temperature management: knowledge, beliefs about capabilities, beliefs about consequences, reinforcement, memory/attention/decision-making, environmental context and resources, social/professional role/identity, social influences, and behavioural regulation. Potential target areas to improve temperature management practices include interventions that address information needs about individual temperature management behaviour as well as patient outcome (feedback), increasing awareness of possible temperature management strategies and guidelines, and a range of equipment and surgical team dynamics that influence temperature management. This study identified several potential target areas for future interventions from nine of the TDF behavioural domains that anesthesiologists perceive to drive their temperature management practices. Future interventions that aim to close the evidence-practice gap in perioperative temperature management may include these targets.

  11. A patient with refractory shock induced by several factors, including obstruction because of a posterior mediastinal hematoma.

    Science.gov (United States)

    Obinata, Mariko; Ishikawa, Kouhei; Osaka, Hiromichi; Mishima, Kentaro; Omori, Kazuhiko; Oode, Yasumasa; Yanagawa, Youichi

    2015-06-01

    A 44-year-old man who drove a motorcycle experienced a collision with the side of another motorcycle. Because he had sustained a high-energy injury to the spinal cord, he was transferred to our hospital. His circulation was unstable, and received tracheal intubation in addition to thoracostomy for the hemothorax. Whole-body computed tomography (CT) revealed multiple fractures, right hemopneumothorax with pulmonary contusion, and minor liver injury. After infusing 5000 mL of lactated Ringer's solution and 10 units of blood, his circulation remained unstable. On a repeat CT examination, the left atrium was found to be compressed by a posterior mediastinal hematoma induced by the fracture of the thoracic spine, and a diagnosis of shock induced by multiple factors, including hemorrhagic, neurogenic, and obstructive mechanisms, was made. After obtaining stable circulation and respirations, internal fixation of the extremities and extubation were performed on the 12th hospital day. Chest CT performed on the 27th day showed the disappearance of compression of the left atrium by the hematoma.

  12. The Temperature Dependence of the Debye-Waller Factor of Magnesium

    DEFF Research Database (Denmark)

    Sledziewska-Blocka, D.; Lebech, Bente

    1976-01-01

    The temperature dependence of the average Debye-Waller factor for magnesium was measured by means of neutron diffraction spectrometry. The experimental results obtained in the temperature range from 5 to 256 K are compared with theoretical calculations, using the harmonic and quasi-harmonic appro......The temperature dependence of the average Debye-Waller factor for magnesium was measured by means of neutron diffraction spectrometry. The experimental results obtained in the temperature range from 5 to 256 K are compared with theoretical calculations, using the harmonic and quasi...

  13. Hydrogeomorphic Classification of Wetlands on Mt. Desert Island, Maine, Including Hydrologic Susceptibility Factors for Wetlands in Acadia National Park

    Science.gov (United States)

    Nielsen, Martha G.

    2006-01-01

    The U.S. Geological Survey, in cooperation with the National Park Service, developed a hydrogeomorphic (HGM) classification system for wetlands greater than 0.4 hectares (ha) on Mt. Desert Island, Maine, and applied this classification using map-scale data to more than 1,200 mapped wetland units on the island. In addition, two hydrologic susceptibility factors were defined for a subset of these wetlands, using 11 variables derived from landscape-scale characteristics of the catchment areas of these wetlands. The hydrologic susceptibility factors, one related to the potential hydrologic pathways for contaminants and the other to the susceptibility of wetlands to disruptions in water supply from projected future changes in climate, were used to indicate which wetlands (greater than 1 ha) in Acadia National Park (ANP) may warrant further investigation or monitoring. The HGM classification system consists of 13 categories: Riverine-Upper Perennial, Riverine-Nonperennial, Riverine- Tidal, Depressional-Closed, Depressional-Semiclosed, Depressional-Open, Depressional-No Ground-Water Input, Mineral Soil Flat, Organic Soil Flat, Tidal Fringe, Lacustrine Fringe, Slope, and Hilltop/Upper Hillslope. A dichotomous key was developed to aid in the classification of wetlands. The National Wetland Inventory maps produced by the U.S. Fish and Wildlife Service provided the wetland mapping units used for this classification. On the basis of topographic map information and geographic information system (GIS) layers at a scale of 1:24,000 or larger, 1,202 wetland units were assigned a preliminary HGM classification. Two of the 13 HGM classes (Riverine-Tidal and Depressional-No Ground-Water Input) were not assigned to any wetlands because criteria for determining those classes are not available at that map scale, and must be determined by more site-specific information. Of the 1,202 wetland polygons classified, which cover 1,830 ha in ANP, 327 were classified as Slope, 258 were

  14. Psychological factors, including alexithymia, in the prediction of cardiovascular risk in HIV infected patients: results of a cohort study.

    Directory of Open Access Journals (Sweden)

    Giustino Parruti

    Full Text Available BACKGROUND: Psychological factors are known predictors of cardiovascular disease in many clinical settings, but data are lacking for HIV infection. We carried out a prospective cohort study to evaluate potential psychological predictors of preclinical and clinical vascular disease in HIV patients. METHODOLOGY/PRINCIPAL FINDINGS: HIV patients were consecutively enrolled. Demographics, viral and immune parameters and traditional cardiovascular predictors were considered; Intima-Media Thickness (c-IMT, continuous measure and Carotid Plaques (CPs, focal thickening ≥1.5 mm were investigated by B-mode ultrasonography; depressive symptoms by the Beck Depression Inventory (BDI-II, Type D personality (Distressed Personality or Type D by the DS14, alexithymia by the Toronto Alexithymia Scale (TAS-20. Vascular outcomes included transient ischemic attacks or stroke, acute coronary syndrome, myocardial or other organ infarction. We enrolled 232 HIV subjects, 73.9% males, aged 44.5±9.9 y, 38.2% with AIDS diagnosis, 18.3% untreated. Mean Nadir CD4 T-cell counts were 237.5±186.2/mmc. Of them, 224 (96.5% attended IMT measurements; 201 (86.6% attended both IMT assessment and psychological profiling. Mean follow-up was 782±308 days. Fifty-nine patients (29.4% had CPs at baseline. Nineteen patients (9.5% had ≥1 vascular event; 12 (6.0% died due to such events (n = 4 or any cause. At baseline cross-sectional multivariate analysis, increasing age, total cholesterol, current smoking and Alexithymia score≥50 were significantly associated with both increased cIMT (linear regression and CPs (logistic regression. At follow-up analysis, log-rank tests and Cox's regression revealed that only older age (p = 0.001, current smoking (p = 0.019 and alexithymia score≥50 (p = 0.013 were independently associated with vascular events. CONCLUSIONS/SIGNIFICANCE: In HIV-infected subjects, the Alexithymic trait emerges as a strong predictor of increased IMT, presence of CPs

  15. Contribution of thermal and nonthermal factors to the regulation of body temperature in humans.

    Science.gov (United States)

    Mekjavic, Igor B; Eiken, Ola

    2006-06-01

    The set point has been used to define the regulated level of body temperature, suggesting that displacements of core temperature from the set point initiate heat production (HP) and heat loss (HL) responses. Human and animal experiments have demonstrated that the responses of sweating and shivering do not coincide at a set point but rather establish a thermoeffector threshold zone. Neurophysiological studies have demonstrated that the sensor-to-effector pathways for HP and HL overlap and, in fact, mutually inhibit each other. This reciprocal inhibition theory, presumably reflecting the manner in which thermal factors contribute to homeothermy in humans, does not incorporate the effect of nonthermal factors on temperature regulation. The present review examines the actions of these nonthermal factors within the context of neuronal models of temperature regulation, suggesting that examination of these factors may provide further insights into the nature of temperature regulation. It is concluded that, although there is no evidence to doubt the existence of the HP and HL pathways reciprocally inhibiting one another, it appears that such a mechanism is of little consequence when comparing the effects of nonthermal factors on the thermoregulatory system, since most of these factors seem to exert their influence in the region after the reciprocal cross-inhibition. At any given moment, both thermal and several nonthermal factors will be acting on the thermoregulatory system. It may, therefore, not be appropriate to dismiss the contribution of either when discussing the regulation of body temperature in humans.

  16. Extended dynamic model for ion diffusion in all-vanadium redox flow battery including the effects of temperature and bulk electrolyte transfer

    Science.gov (United States)

    Badrinarayanan, Rajagopalan; Zhao, Jiyun; Tseng, K. J.; Skyllas-Kazacos, Maria

    2014-12-01

    As with all redox flow batteries, the Vanadium Redox flow Battery (VRB) can suffer from capacity loss as the vanadium ions diffuse at different rates leading to a build-up on one half-cell and dilution on the other. In this paper an extended dynamic model of the vanadium ion transfer is developed including the effect of temperature and bulk electrolyte transfer. The model is used to simulate capacity decay for a range of different ion exchange membranes that are being used in the VRB. The simulations show that Selemion CMV and Nafion 115 membranes have similar behavior where the impact of temperature on capacity loss is highest within the first 100 cycles. The results for Selemion AMV membrane however are seen to be very different where the capacity loss at different temperatures observed to increase linearly with increasing charging/discharging cycles. The model is made more comprehensive by including the effect of bulk electrolyte transfer. A volume change of 19% is observed in each half-cell for Nafion 115 membrane based on the simulation parameters. The effect of this change in volume directly affects concentration, and the characteristics are analyzed for each vanadium species as well as the overall concentration in the half-cells.

  17. Excitation and charge transfer in He/sup +/ + H collisions. A molecular approach including two-electron translation factors

    Energy Technology Data Exchange (ETDEWEB)

    Errea, L.F.; Mendez, L.; Riera, A.

    1983-06-01

    In a previous paper we have pointed out that the common-translation-factor (CTF) method is the only one which, at present, and within the framework of the molecular model of atomic collisions, can be shown to be both convergent and computationally fast, even for many-electron systems. In this Communication we check that this second statement is correct, presenting, for the first time, a molecular calculation involving two-electron translation factors, for He/sup +/ + H collisions. A careful study of the sensitivity of the calculated cross sections to the choice of the CTF is performed, and conclusions on that sensitivity are drawn, for several types of processes.

  18. Biot Critical Frequency Applied as Common Friction Factor for Chalk with Different Pore Fluids and Temperatures

    DEFF Research Database (Denmark)

    Andreassen, Katrine Alling; Fabricius, Ida Lykke

    2010-01-01

    and we propose that the fluid effect on mechanical properties of highly porous chalk may be the result of liquid‐solid friction. Applying a different strain or stress rate is influencing the rock strength and needs to be included. The resulting function is shown to relate to the material dependent...... and rate independent b-factor used when describing the time dependent mechanical properties of soft rock or soils. As a consequence it is then possible to further characterize the material constant from the porosity and permeability of the rock as well as from pore fluid density and viscosity which......Injection of water into chalk hydrocarbon reservoirs has lead to mechanical yield and failure. Laboratory experiments on chalk samples correspondingly show that the mechanical properties of porous chalk depend on pore fluid and temperature. Water has a significant softening effect on elastic...

  19. Biot Critical Frequency Applied as Common Friction Factor for Chalk with Different Pore Fluids and Temperatures

    DEFF Research Database (Denmark)

    Andreassen, Katrine Alling; Fabricius, Ida Lykke

    2010-01-01

    Injection of water into chalk hydrocarbon reservoirs has lead to mechanical yield and failure. Laboratory experiments on chalk samples correspondingly show that the mechanical properties of porous chalk depend on pore fluid and temperature. Water has a significant softening effect on elastic...... and we propose that the fluid effect on mechanical properties of highly porous chalk may be the result of liquid‐solid friction. Applying a different strain or stress rate is influencing the rock strength and needs to be included. The resulting function is shown to relate to the material dependent...... and rate independent b-factor used when describing the time dependent mechanical properties of soft rock or soils. As a consequence it is then possible to further characterize the material constant from the porosity and permeability of the rock as well as from pore fluid density and viscosity which...

  20. Line parameters including temperature dependences of self- and air-broadened line shapes of 12C16O2: 1.6-μm region

    Science.gov (United States)

    Devi, V. Malathy; Benner, D. Chris; Sung, Keeyoon; Brown, Linda R.; Crawford, Timothy J.; Miller, Charles E.; Drouin, Brian J.; Payne, Vivienne H.; Yu, Shanshan; Smith, Mary Ann H.; Mantz, Arlan W.; Gamache, Robert R.

    2016-07-01

    Pressure-broadened line shapes in the 30013←00001 (ν1+4 ν20 +ν3) band of 12C16O2 at 6228 cm-1 are reanalyzed using new spectra recorded with sample temperatures down to 170 K. High resolution, high signal-to-noise (S/N) laboratory measurements of line shapes (Lorentz air- and self-broadened half-width coefficients, pressure-shift coefficients and off-diagonal relaxation matrix element coefficients) as a function of gas sample temperatures for various pressures and volume mixing ratios are presented. The spectra were recorded using two different Fourier transform spectrometers (FTS): (1) the McMath-Pierce FTS located at the National Solar Observatory on Kitt Peak, Arizona (and reported in Devi et al., J Mol Spectrosc 2007;245:52-80) and, (2) the Bruker IFS-125HR FTS at the Jet Propulsion Laboratory in Pasadena, California. The 19 spectra taken at Kitt Peak were all recorded near room temperature while the 27 Bruker spectra were acquired both at room temperature and colder temperatures (170-296 K). Various spectral resolutions (0.004-0.011 cm-1), absorption path lengths (2.46-121 m) and CO2 samples (natural and 12C-enriched) were included in the dataset. To maximize the accuracies of the various retrieved line parameters, a multispectrum nonlinear least squares spectrum fitting software program was used to adjust the ro-vibrational constants (G,B,D etc.) and intensity parameters (including Herman-Wallis terms) instead of directly measuring the individual line positions and intensities. To minimize systematic residuals, line mixing (via off-diagonal relaxation matrix elements) and quadratic speed dependence parameters were included in the analysis. Contributions from other weakly absorbing bands: the 30013←00001 and 30012←00001 bands of 13C16O2, the 30013←00001 band of 12C16O18O, hot bands 31113←01101 and 32212←02201 of 12C16O2, as well as the 40013←10001 and the 40014←10002 bands of 12C16O2, present within the fitted interval were also measured

  1. The Coupling of Treeline Elevation and Temperature is Mediated by Non-Thermal Factors on the Tibetan Plateau

    Directory of Open Access Journals (Sweden)

    Yafeng Wang

    2017-04-01

    Full Text Available Little is known about the relationships between treeline elevation and climate at regional and local scales. It is compelling to fill this research gap with data from the Tibetan Plateau where some of the highest alpine treelines in the world are found. This research question partially results from the lack of in situ temperature data at treeline sites. Herein, treeline variables (e.g., elevation, topography, tree species and temperature data were collected from published investigations performed during this decade on the Tibetan Plateau. Temperature conditions near treeline sites were estimated using global databases and these estimates were corrected by using in situ air temperature measurements. Correlation analyses and generalized linear models were used to evaluate the effects of different variables on treeline elevation including thermal (growing-season air temperatures and non-thermal (latitude, longitude, elevation, tree species, precipitation, radiation factors. The commonality analysis model was applied to explore how several variables (July mean temperature, elevation of mountain peak, latitude were related to treeline elevation. July mean temperature was the most significant predictor of treeline elevation, explaining 55% of the variance in treeline elevation across the Tibetan Plateau, whereas latitude, tree species, and mountain elevation (mass-elevation effect explained 30% of the variance in treeline elevation. After considering the multicollinearity among predictors, July mean temperature (largely due to the influence of minimum temperature still showed the strongest association with treeline elevation. We conclude that the coupling of treeline elevation and July temperature at a regional scale is modulated by non-thermal factors probably acting at local scales. Our results contribute towards explaining the decoupling between climate warming and treeline dynamics.

  2. Comparative analysis and approximations of space-charge formation in Langmuir probes with plane, cylindrical and spherical electrodes including temperature effects

    Energy Technology Data Exchange (ETDEWEB)

    Valdeblanquez, Eder [Departamento de Fisica, Facultad de IngenierIa, Universidad del Zulia, Apartado 4011- A 526, Maracaibo, Venezuela and Centro de Investigacion de Matematicas Aplicadas Facultad de IngenierIa, Universidad del Zulia, Apartado 10486, Maracaibo (Venezuela, Bolivarian Republic of)], E-mail: eder@luz.edu.ve

    2008-10-15

    In this paper the space-charge effects in Langmuir probes are compared for different kinds of symmetries: plane, cylindrical and spherical. A detailed analysis is performed here including temperature effects, and therefore kinetic theory is used instead of fluid equations as used by other authors. The nonlinear equations obtained here have been solved first by numerical computation and later by approximations using Bessel functions. The accuracy of each approximation is also discussed. Space-charge effects are more important in plane geometries than in the case of cylindrical or spherical symmetries.

  3. Deduction of bond length changes of symmetric molecules from experimental vibrational progressions, including a topological mass factor.

    Science.gov (United States)

    Su, Jing; Wei, Fan; Schwarz, W H E; Li, Jun

    2012-12-20

    The change ΔR(x) of bond length R(x) for atom X in a molecule upon electronic transition can be derived from the intensities I(i) of the vibrational stretching progression v = 0 → i of the electronic absorption or emission spectrum. In many cases, a simple model is sufficient for a reasonable estimate of ΔR(x). For symmetric molecules, however, conceptual problems in the literature of many decades are evident. The breathing modes of various types of symmetric molecules X(n) and AX(n) (A at the center) are here discussed. In the simplest case of a harmonic vibration of the same mode in the initial and final electronic states, we obtain ΔR(x) ≈ [2S/(ωm(x))](1/2)/w(1/2) (all quantities in atomic units). ω and S are respectively the observed vibrational quanta and the Huang-Rhys factor (corresponding, e.g., to the vibrational intensity ratio I(1)/I(0) ≈ S), m(x) is the mass of vibrating atom X, and w is a topological factor for molecule X(n) or AX(n). The factor 1/w(1/2) in the expression for ΔR(x) must not be neglected. The spectra and bond length changes of several symmetric molecules AX(n) and X(n) are discussed. The experimental bond length changes correctly derived with factor 1/w(1/2) are verified by reliable quantum chemical calculations.

  4. Catchment process affecting drinking water quality, including the significance of rainfall events, using factor analysis and event mean concentrations.

    Science.gov (United States)

    Cinque, Kathy; Jayasuriya, Niranjali

    2010-12-01

    To ensure the protection of drinking water an understanding of the catchment processes which can affect water quality is important as it enables targeted catchment management actions to be implemented. In this study factor analysis (FA) and comparing event mean concentrations (EMCs) with baseline values were techniques used to asses the relationships between water quality parameters and linking those parameters to processes within an agricultural drinking water catchment. FA found that 55% of the variance in the water quality data could be explained by the first factor, which was dominated by parameters usually associated with erosion. Inclusion of pathogenic indicators in an additional FA showed that Enterococcus and Clostridium perfringens (C. perfringens) were also related to the erosion factor. Analysis of the EMCs found that most parameters were significantly higher during periods of rainfall runoff. This study shows that the most dominant processes in an agricultural catchment are surface runoff and erosion. It also shows that it is these processes which mobilise pathogenic indicators and are therefore most likely to influence the transport of pathogens. Catchment management efforts need to focus on reducing the effect of these processes on water quality.

  5. Line parameters including temperature dependences of air- and self-broadened line shapes of 12C16O2: 2.06-μm region

    Science.gov (United States)

    Benner, D. Chris; Devi, V. Malathy; Sung, Keeyoon; Brown, Linda R.; Miller, Charles E.; Payne, Vivienne H.; Drouin, Brian J.; Yu, Shanshan; Crawford, Timothy J.; Mantz, Arlan W.; Smith, Mary Ann H.; Gamache, Robert R.

    2016-08-01

    This study reports the results from analyzing a number of high resolution, high signal-to-noise ratio (S/N) spectra in the 2.06-μm spectral region for pure CO2 and mixtures of CO2 in dry air. A multispectrum nonlinear least squares curve fitting technique has been used to retrieve the various spectral line parameters. The dataset includes 27 spectra: ten pure CO2, two 99% 13C-enriched CO2 and fifteen spectra of mixtures of 12C-enriched CO2 in dry air. The spectra were recorded at various gas sample temperatures between 170 and 297 K. The absorption path lengths range from 0.347 to 49 m. The sample pressures for the pure CO2 spectra varied from 1.1 to 594 Torr; for the two 13CO2 spectra the pressures were ∼10 and 146 Torr. For the air-broadened spectra, the pressures of the gas mixtures varied between 200 and 711 Torr with CO2 volume mixing ratios ranging from 0.014% to 0.203%. The multispectrum fitting technique was applied to fit simultaneously all these spectra to retrieve consistent set of line positions, intensities, and line shape parameters including their temperature dependences; for this, the Voigt line shape was modified to include line mixing (via the relaxation matrix formalism) and quadratic speed dependence. The new results are compared to select published values, including recent ab initio calculations. These results are required to retrieve the column averaged dry air mole fraction (XCO2) from space-based observations, such as the Orbiting Carbon Observatory-2 (OCO-2) satellite mission that NASA launched in July 2014.

  6. Postnatal visual deprivation in rats regulates several retinal genes and proteins, including differentiation-associated fibroblast growth factor-2.

    Science.gov (United States)

    Prokosch-Willing, Verena; Meyer zu Hoerste, Melissa; Mertsch, Sonja; Stupp, Tobias; Thanos, Solon

    2015-01-01

    Little is known about the retinal cellular basis of amblyopia, which is a developmental disease characterized by impaired visual acuity. This study examined the retinal transcripts associated with experimentally induced unilateral amblyopia in rats. Surgical tarsorrhaphy of the eyelids on one side was performed in pups prior to eye opening at postnatal day 14, thereby preventing any visual experience. This condition was maintained for over 2 months, after which electroretinograms (ERGs) were recorded, the retinal ganglion cell (RGC) arrangement and number were determined using neuroanatomical tracing, the retinal transcripts were studied using microarray analysis, regulated mRNAs were confirmed with quantitative reverse-transcriptase PCR, and proteins were stained using Western blotting and immunohistochemistry. An attenuated ERG was found in eyes that were deprived of visual experience. Retrograde neuroanatomical staining disclosed a larger number of RGCs within the retina on the visually deprived side compared to the non-deprived, control side, and a multilayered distribution of RGCs. At the retinomic level, several transcripts associated with retinal differentiation, such as fibroblast growth factor 2 (FGF-2), were either up- or downregulated. Most of the transcripts could be verified at the mRNA level. To unravel the role of a differentiation-associated protein, we tested FGF-2 in dissociated postnatal retinal cell cultures and found that FGF-2 is a potent factor triggering ganglion cell differentiation. The data suggest that visual experience shapes the postnatal retinal differentiation, whereas visual deprivation induces changes at the functional, cellular and molecular levels within the retina.

  7. Generating induced pluripotent stem cells from common marmoset (Callithrix jacchus) fetal liver cells using defined factors, including Lin28.

    Science.gov (United States)

    Tomioka, Ikuo; Maeda, Takuji; Shimada, Hiroko; Kawai, Kenji; Okada, Yohei; Igarashi, Hiroshi; Oiwa, Ryo; Iwasaki, Tsuyoshi; Aoki, Mikio; Kimura, Toru; Shiozawa, Seiji; Shinohara, Haruka; Suemizu, Hiroshi; Sasaki, Erika; Okano, Hideyuki

    2010-09-01

    Although embryonic stem (ES) cell-like induced pluripotent stem (iPS) cells have potential therapeutic applications in humans, they are also useful for creating genetically modified human disease models in nonhuman primates. In this study, we generated common marmoset iPS cells from fetal liver cells via the retrovirus-mediated introduction of six human transcription factors: Oct-3/4, Sox2, Klf4, c-Myc, Nanog, and Lin28. Four to five weeks after introduction, several colonies resembling marmoset ES cells were observed and picked for further expansion in ES cell medium. Eight cell lines were established, and validation analyses of the marmoset iPS cells followed. We detected the expression of ES cell-specific surface markers. Reverse transcription-PCR showed that these iPS cells expressed endogenous Oct-3/4, Sox2, Klf4, c-Myc, Nanog and Lin28 genes, whereas all of the transgenes were silenced. Karyotype analysis showed that two of three iPS cell lines retained a normal karyotype after a 2-month culture. Both embryoid body and teratoma formation showed that marmoset iPS cells had the developmental potential to give rise to differentiated derivatives of all three primary germ layers. In summary, we generated marmoset iPS cells via the transduction of six transcription factors; this provides a powerful preclinical model for studies in regenerative medicine.

  8. Broadening the etiological discourse on Alzheimer's disease to include trauma and posttraumatic stress disorder as psychosocial risk factors.

    Science.gov (United States)

    Burnes, David P R; Burnette, Denise

    2013-08-01

    Biomedical perspectives have long dominated research on the etiology and progression of Alzheimer's disease (AD); yet these approaches do not solely explain observed variations in individual AD trajectories. More robust biopsychosocial models regard the course of AD as a dialectical interplay of neuropathological and psychosocial influences. Drawing on this broader conceptualization, we conducted an extensive review of empirical and theoretical literature on the associations of trauma, posttraumatic stress disorder (PTSD) and AD to develop a working model that conceptualizes the role of psychosocial stressors and physiological mechanisms in the onset and course of AD. The proposed model suggests two pathways. In the first, previous life trauma acts as a risk factor for later-life onset of AD, either directly or mediated by PTSD or PTSD correlates. In the second, de novo AD experiential trauma is associated with accelerated cognitive decline, either directly or mediated through PTSD or PTSD correlates. Evidence synthesized in this paper indicates that previous life trauma and PTSD are strong candidates as psychosocial risk factors for AD and warrant further empirical scrutiny. Psychosocial and neurological-based intervention implications are discussed. A biopsychosocial approach has the capacity to enhance understanding of individual AD trajectories, moving the field toward 'person-centered' models of care.

  9. The cerium magnetic form factor and diffuse polarization in CeRh3B2 as functions of temperature

    Science.gov (United States)

    Givord, F.; Boucherle, J.-X.; Lelièvre-Berna, E.; Lejay, P.

    2004-03-01

    In the compound CeRh3B2, a rather special polarization of the conduction electrons along the c-chains of cerium atoms had been previously reported at low temperatures (Alonso et al 1998 J. Magn. Magn. Mater. 177-181 1048). The distribution of the CeRh3B2 magnetization has now been studied as a function of temperature up to 150 K—that is, above the Curie temperature of 115 K. The magnetization density maps have been obtained from polarized neutron diffraction experiments by using the maximum entropy method. The cerium form factor has also been analysed. Calculations of the form factor including several multiplets are developed and it is shown that it is necessary to take into account the influence of the higher multiplet of the Ce3+ ion. This result is coherent with the observation of a peak at high energy in the inelastic neutron spectra, indicating a very large crystal electric field splitting. Both analyses lead to the same conclusion that, on heating, the diffuse negative magnetization observed at low temperature along the cerium chains disappears at the magnetic ordering temperature. The influence of the second multiplet of the Ce3+ ion could be part of the explanation for the low value of the 4f moment and the large Curie temperature in CeRh3B2.

  10. Complex analysis of Askaryan radiation: A fully analytic treatment including the LPM effect and Cascade Form Factor

    Science.gov (United States)

    Hanson, Jordan C.; Connolly, Amy L.

    2017-05-01

    The Askaryan effect describes coherent electromagnetic radiation from high-energy cascades in dense media with a collective charge. We present an analytic model of Askaryan radiation that accounts simultaneously for the three-dimensional form factor of the cascade, and quantum mechanical cascade elongation via the Landau-Pomeranchuk-Migdal effect. These calculations, and the associated open-source code, allow the user to avoid computationally intensive Monte Carlo cascade simulations. Searches for cosmogenic neutrinos in Askaryan-based detectors benefit from computational speed, because scans of Askaryan parameter-space are required to match neutrino signals. The Askaryan field is derived from cascade equations verified with Geant4 simulations, and compared with prior numerical and semi-analytic calculations. Finally, instructive cases of the model are transformed from the Fourier domain to the time-domain. Next-generation in situ detectors like ARA and ARIANNA can use analytic time-domain signal models to search for correlations with event candidates.

  11. Complex Analysis of Askaryan Radiation: A Fully Analytic Treatment including the LPM effect and Cascade Form Factor

    CERN Document Server

    Hanson, Jordan C

    2016-01-01

    The Askaryan effect describes coherent electromagnetic radiation from the collective charge within high-energy cascades in dense media. We present the first fully analytic model of Askaryan radiation that accounts simultaneously for the three-dimensional form factor of the electromagnetic cascade and the Landau-Pomeranchuk-Migdal (LPM) effect. Analytic calculations avoid computationally intensive Monte Carlo simulations of the cascades. Searches for cosmogenic neutrinos in Askaryan- based detectors benefit from computational speed, because neutrino event parameters affect the shape of the electromagnetic field, requiring scans of parameter space. The Askaryan field is derived and verified against Geant4 simulations, and compared with prior numerical and semi-analytic calculations. Finally, two special cases of the model are transformed from the Fourier domain to the time-domain, analytically. Next-generation in situ detectors like ARA and ARIANNA can use analytic time-domain signal models to search for phase ...

  12. Relationship between outdoor temperature and cardiovascular disease risk factors in older people

    Science.gov (United States)

    Barry, Sarah JE; Whincup, Peter H; Wannamethee, S Goya; Lowe, Gordon DO; Jefferis, Barbara J; Lennon, Lucy; Welsh, Paul; Ford, Ian; Sattar, Naveed; Morris, Richard W

    2016-01-01

    Background Previous studies demonstrated that lower outdoor temperatures increase the levels of established cardiovascular disease risk factors, such as blood pressure and lipids. Whether or not low temperatures increase novel cardiovascular disease risk factors levels is not well studied. The aim was to investigate associations of outdoor temperature with a comprehensive range of established and novel cardiovascular disease risk factors in two large Northern European studies of older adults, in whom cardiovascular disease risk is increased. Design and methods Data came from the British Regional Heart Study (4252 men aged 60–79 years) and the Prospective Study of Pravastatin in the Elderly at Risk (5804 men and women aged 70–82 years). Associations between outdoor temperature and cardiovascular disease risk factors were quantified in each study and then pooled using a random effects model. Results With a 5℃ lower mean temperature, total cholesterol was 0.04 mmol/l (95% confidence interval (CI) 0.02–0.07) higher, low density lipoprotein cholesterol was 0.02 mmol/l (95% CI 0.01–0.05) higher and SBP was 1.12 mm Hg (95% CI 0.60–1.64) higher. Among novel cardiovascular disease risk factors, C-reactive protein was 3.3% (95% CI 1.0–5.6%) higher, interleukin-6 was 2.7% (95% CI 1.1–4.3%) higher, and vitamin D was 11.2% (95% CI 1.0–20.4%) lower. Conclusions Lower outdoor temperature was associated with adverse effects on cholesterol, blood pressure, circulating inflammatory markers, and vitamin D in two older populations. Public health approaches to protect the elderly against low temperatures could help in reducing the levels of several cardiovascular disease risk factors. PMID:27899528

  13. Relationship between outdoor temperature and cardiovascular disease risk factors in older people.

    Science.gov (United States)

    Sartini, Claudio; Barry, Sarah Je; Whincup, Peter H; Wannamethee, S Goya; Lowe, Gordon DO; Jefferis, Barbara J; Lennon, Lucy; Welsh, Paul; Ford, Ian; Sattar, Naveed; Morris, Richard W

    2017-03-01

    Background Previous studies demonstrated that lower outdoor temperatures increase the levels of established cardiovascular disease risk factors, such as blood pressure and lipids. Whether or not low temperatures increase novel cardiovascular disease risk factors levels is not well studied. The aim was to investigate associations of outdoor temperature with a comprehensive range of established and novel cardiovascular disease risk factors in two large Northern European studies of older adults, in whom cardiovascular disease risk is increased. Design and methods Data came from the British Regional Heart Study (4252 men aged 60-79 years) and the Prospective Study of Pravastatin in the Elderly at Risk (5804 men and women aged 70-82 years). Associations between outdoor temperature and cardiovascular disease risk factors were quantified in each study and then pooled using a random effects model. Results With a 5℃ lower mean temperature, total cholesterol was 0.04 mmol/l (95% confidence interval (CI) 0.02-0.07) higher, low density lipoprotein cholesterol was 0.02 mmol/l (95% CI 0.01-0.05) higher and SBP was 1.12 mm Hg (95% CI 0.60-1.64) higher. Among novel cardiovascular disease risk factors, C-reactive protein was 3.3% (95% CI 1.0-5.6%) higher, interleukin-6 was 2.7% (95% CI 1.1-4.3%) higher, and vitamin D was 11.2% (95% CI 1.0-20.4%) lower. Conclusions Lower outdoor temperature was associated with adverse effects on cholesterol, blood pressure, circulating inflammatory markers, and vitamin D in two older populations. Public health approaches to protect the elderly against low temperatures could help in reducing the levels of several cardiovascular disease risk factors.

  14. Effect of yoga practices on pulmonary function tests including transfer factor of lung for carbon monoxide (TLCO) in asthma patients.

    Science.gov (United States)

    Singh, Savita; Soni, Ritu; Singh, K P; Tandon, O P

    2012-01-01

    Prana is the energy, when the self-energizing force embraces the body with extension and expansion and control, it is pranayama. It may affect the milieu at the bronchioles and the alveoli particularly at the alveolo-capillary membrane to facilitate diffusion and transport of gases. It may also increase oxygenation at tissue level. Aim of our study is to compare pulmonary functions and diffusion capacity in patients of bronchial asthma before and after yogic intervention of 2 months. Sixty stable asthmatic-patients were randomized into two groups i.e group 1 (Yoga training group) and group 2 (control group). Each group included thirty patients. Lung functions were recorded on all patients at baseline, and then after two months. Group 1 subjects showed a statistically significant improvement (Pyoga practice. Quality of life also increased significantly. It was concluded that pranayama & yoga breathing and stretching postures are used to increase respiratory stamina, relax the chest muscles, expand the lungs, raise energy levels, and calm the body.

  15. Lifestyle modification induced weight loss and changes of cardiometabolic risk factors including lowering of inflammatory response in obese children.

    Science.gov (United States)

    Motykova, Eva; Zlatohlavek, Lukáš; Prusikova, Martina; Lanska, Vera; Ceska, Richard; Vasickova, Ludmila; Vrablik, Michal

    2011-01-01

    Obesity is associated with increased inflammation which represents a link to atherosclerosis and cardiovascular disease. Lipoprotein associated phospholipase A2 (Lp-PLA2) is an independent marker of inflammation and atherosclerosis risk. To assess the impact of weight loss on metabolic markers of atherosclerosis including Lp-PLA2 we examined a group of Czech non-diabetic obese/overweight children exposed to a lifestyle intervention. Fourty unrelated overweight/obese non-diabetic Czech children (13.7 ± 2.1 years, average BMI at baseline 29.8 ± 2.6 kg/m2) underwent 4 weeks of lifestyle modification (reduction of energy intake to age matched optimum and supervised physical activity). Anthropometrical and biochemical variables were determined at baseline and after the intervention. Lp-PLA2 mass concentration was assessed using the ELISA kit. Wilcocson's rank test and Spearman's correlation were used for statistical analysis. A significant decrease of BMI and waist circumference was associated with significant changes of plasma lipoprotein and glycaemia levels. Mass concentration of Lp-PLA2 at the baseline was 402 ± 94 μg/ml, after the intervention 368 ± 105 μg/ml (p=0.008). Change in Lp-PLA2 was associated with triglyceride level decrease (p=0.009). Intensive lifestyle modification leading to body weight decrease results in significant changes of plasma lipoprotein levels and, also, a drop of Lp-PLA2 levels in paediatric obese patients. However, even after the intervention Lp-PLA2 concentrations in this patient group remain elevated suggesting possible increased atherosclerosis risk in later life. © 2011 Neuroendocrinology Letters

  16. Temperature: a prolonged confounding factor on cholinesterase activity in the tropical reef fish Acanthochromis polyacanthus.

    Science.gov (United States)

    Botté, Emmanuelle S; Smith-Keune, Carolyn; Jerry, Dean R

    2013-09-15

    Cholinesterase activity usually decreases in fish exposed to anticholinesterase compounds such as organophosphate and carbamate pesticides. Here we show that tropical reef fish Acanthochromis polyacanthus (or spiny damsel) also exhibits a decrease in ChE activity when exposed to elevated temperature from 28°C to 32°C or 34°C after 4 days. We further demonstrate that the decline persists even after 7 days of recovery at control temperature. This is the first report of a drop in ChE activity in fish as temperature increases. Our results strongly suggest the need for long-term monitoring of water temperature in the field prior to sampling A. polyacanthus for toxicology studies, as temperature is a prolonged and confounding factor for ChE activity in this species.

  17. Significance and influence of the ambient temperature as a rate factor of steel reinforcement corrosion

    Indian Academy of Sciences (India)

    V Živica

    2002-10-01

    The rate of corrosion of reinforcement being an electrochemical process, undoubtedly is dependent even on the level of the ambient temperature. Therefore, the ambient temperature seems to be an important factor of the corrosion rate and the durability of the reinforced concrete structures in aggressive environment. The present data on the influence and significance of the ambient temperature in the process of corrosion of reinforcement of the reinforced structures are surprisingly limited and poor. It seems that it is supposed to be a simple increase of corrosion rate when the ambient temperature is increased. The lack of information was a motivation for the present study. It was aimed at the experimental research of the influence of the increase of the ambient temperature on the rate of chloride induced corrosion of steel reinforcement. The results obtained show that the influence of the studied factor is more complex showing an acceleration effect till a temperature of 40°C diversified by the inhibition effects with further increase of the ambient temperature.

  18. Single-crystal sapphire resonator at millikelvin temperatures: Observation of thermal bistability in high- Q factor whispering gallery modes

    Science.gov (United States)

    Creedon, Daniel L.; Tobar, Michael E.; Le Floch, Jean-Michel; Reshitnyk, Yarema; Duty, Timothy

    2010-09-01

    Resonance modes in single crystal sapphire (α-Al2O3) exhibit extremely high electrical and mechanical Q factors ( ≈109 at 4 K), which are important characteristics for electromechanical experiments at the quantum limit. We report the cool down of a bulk sapphire sample below superfluid liquid-helium temperature (1.6 K) to as low as 25 mK. The electromagnetic properties were characterized at microwave frequencies, and we report the observation of electromagnetically induced thermal bistability in whispering gallery modes due to the material T3 dependence on thermal conductivity and the ultralow dielectric loss tangent. We identify “magic temperatures” between 80 and 2100 mK, the lowest ever measured, at which the onset of bistability is suppressed and the frequency-temperature dependence is annulled. These phenomena at low temperatures make sapphire suitable for quantum metrology and ultrastable clock applications, including the possible realization of the quantum-limited sapphire clock.

  19. The Importance of Water Temperature Fluctuations in Relation to the Hydrological Factor. Case Study – Bistrita River Basin (Romania

    Directory of Open Access Journals (Sweden)

    Cojoc Gianina Maria

    2014-10-01

    Full Text Available The increase in most components of the climate over the past 50 years, including air and water temperature, is a real phenomenon, as attested by the numerous specialized researches according to IPCC (2013. The water temperature is one of the most important climatic components in analyzing the hydrological regime of the Bistrita River (Romania. The thermal regime of the Bistrita River basin and the frost phenomena associated with the risk factor are particularly important and frequently appear in this area. In recent years, under the Siret Water Basin Administration, this parameter was permanently monitored, so we could do an analysis, which shows that the water temperature fluctuations, influenced by air temperature, lead to the emergence of the ice jam phenomenon. The present study aims to analyze the water temperature, as compared to the air temperature, and the effect of these components on the liquid flow regime (the values were recorded at the hydrological stations on the main course of the Bistrita River. The negative effects resulted from the ice jam phenomenon require developing methods of damage prevention and defense. The frost phenomena recorded after the construction of the Bicaz dam are analyzed in this article

  20. Temperature-Related Risk Factors for the Occurrence of Campylobacter in Broilers in Iceland

    Science.gov (United States)

    Introduction A summertime increased risk of Campylobacter is well-established in humans and broilers. Our objective was to identify temperature-related risk factors for the colonization of broiler flocks with Campylobacter in Iceland, with an assumption that flies play a role in the epidemiology an...

  1. Steel Temperature Compensating Model With Multi-Factor Coupling Based on Ladle Thermal State

    Institute of Scientific and Technical Information of China (English)

    WU Peng-fei; XU An-jun; TIAN Nai-yuan; HE Dong-feng

    2012-01-01

    Combined with the parameters of the production process of a steel factory, numerical simulations for a new ladle from preheating to turnover are conducted using the finite element analysis system software (ANSYS). The measured data proved that the simulated results are reliable. The effects of preheating time, thermal cycling times, and empty package time on steel temperature are calculated, an ideal preheating time is provided, besides, based on the analysis of a single factor and use the nonlinear analysis method, a steel temperature compensating model with di- versified coupling factors is proposed, with the largest error of the present coupling model at 1. 462 ~C, and the er- rors between actual and target steel temperature in tundish after the model is applied to practical production are basi- cally controlled within -4-6 ~C, which can meet the accuracy of the manufacturer and has a practical guiding significance for the production in steelmaking workshops.

  2. Fe(II) Spin Transition Materials Including an Amino-Ester 1,2,4-Triazole Derivative, Operating at, below, and above Room Temperature.

    Science.gov (United States)

    Dîrtu, Marinela M; Naik, Anil D; Rotaru, Aurelian; Spinu, Leonard; Poelman, Dirk; Garcia, Yann

    2016-05-02

    A new family of one-dimensional Fe(II) 1,2,4-triazole spin transition coordination polymers for which a modification of anion and crystallization solvent can tune the switching temperature over a wide range, including the room temperature region, is reported. This series of materials was prepared as powders after reaction of ethyl-4H-1,2,4-triazol-4-yl-acetate (αEtGlytrz) with an iron salt from a MeOH/H2O medium affording: [Fe(αEtGlytrz)3](ClO4)2 (1); [Fe(αEtGlytrz)3](ClO4)2·CH3OH (2); [Fe(αEtGlytrz)3](NO3)2·H2O (3); [Fe(αEtGlytrz)3](NO3)2 (4); [Fe(αEtGlytrz)3](BF4)2·0.5H2O (5); [Fe(αEtGlytrz)3](BF4)2 (6); and [Fe(αEtGlytrz)3](CF3SO3)2·2H2O (7). Their spin transition properties were investigated by (57)Fe Mossbauer spectroscopy, superconducting quantum interference device (SQUID) magnetometry, and differential scanning calorimetry (DSC). The temperature dependence of the high-spin molar fraction derived from (57)Fe Mössbauer spectroscopy in 1 reveals an abrupt single step transition between low-spin and high-spin states with a hysteresis loop of width 5 K (Tc(↑) = 296 K and Tc(↓) = 291 K). The properties drastically change with modification of anion and/or lattice solvent. The transition temperatures, deduced by SQUID magnetometry, shift to Tc(↑) = 273 K and Tc(↓) = 263 K for (2), Tc(↑) = 353 K and Tc(↓) = 333 K for (3), Tc(↑) = 338 K and Tc(↓) = 278 K for (4), T(↑) = 320 K and T(↓) = 305 K for (5), Tc(↑) = 106 K and Tc(↓) = 92 K for (6), and T(↑) = 325 K and T(↓) = 322 K for (7). Annealing experiments of 3 lead to a change of the morphology, texture, and magnetic properties of the sample. A dehydration/rehydration process associated with a spin state change was analyzed by a mean-field macroscopic master equation using a two-level Hamiltonian Ising-like model for 3. A new structural-property relationship was also identified for this series of materials [Fe(αEtGlytrz)3](anion)2·nSolvent based on Mössbauer and DSC

  3. Assessment of climatic factors influence on interannual changes in the global surface air temperature

    Science.gov (United States)

    Gusakova, Maria; Karlin, Lev

    2014-05-01

    A model to assess a number of factors such as TSI, albedo, cloudiness and greenhouse gases including water vapour affecting global surface air temperature (SAT) changes has been developed. To develop the model solar energy transformation in the atmosphere and the other radiation fluxes transformation were investigated. It's a common knowledge that some part of the incoming solar energy is reflected into space by the Earth's surface, aerosol and cloud particles. A contribution of these components to changes in the reflected solar energy was assessed on the basis of developed linear parameterization. During the period of 2001 - 2010, clouds were found to be the basic contributor to the changes in reflected shortwave radiation. Some part of outgoing terrestrial radiation is retained in the atmosphere by greenhouse gases, water vapour and cloudiness. A contribution of these components to changes in the absorbed longwave radiation was assessed on the basis of developed linear parameterization. It was estimated that the contribution of water vapour was dominant during the analyzed period. The developed parameterization of global albedo made it possible to assess the contribution of TSI to global SAT changes. Making use of the parameterizations listed above the model has been improved. The model calculations showed that the our projections of global SAT to 2030 were lower than IPCC estimates.

  4. A Variationally Formulated Problem of the Stationary Heat Conduction in a Plate with Radiation Reduction Factor Increased under Temperature

    Directory of Open Access Journals (Sweden)

    V. S. Zarubin

    2016-01-01

    dependence of the absorption factor on the local intensity of this radiation. Furthermore, it can be a significant dependence of this factor on the local value of the material temperature, reflecting the above-mentioned relationship between the absorption of electromagnetic wave energy and the excitation of material microparticles. This process can be described by Boltzmann distribution function that comprises the energy to activate microparticles and the local value of temperature.This paper presents a variational formulation of the nonlinear problem of stationary heat conduction in a plate for the case when the radiation reduction factor in relation to the Bouguer law depends on the local temperature. This formulation includes a functional that can have several fixed points corresponding to different steady states of the plate temperature. Analysis of the properties of this functional enabled us to identify the stationary points, which correspond to the realized temperature distribution in the plate.

  5. A temperature dependent slip factor based thermal model for friction stir welding of stainless steel

    Indian Academy of Sciences (India)

    M Selvaraj

    2013-12-01

    This paper proposes a new slip factor based three-dimensional thermal model to predict the temperature distribution during friction stir welding of 304L stainless steel plates. The proposed model employs temperature and radius dependent heat source to study the thermal cycle, temperature distribution, power required, the effect of process parameters on heat generation per mm length of the weld and peak temperature during the friction stir welding process. Simulations of friction stir welding process were carried out on 304L stainless steel workpieces for various rotational and welding speeds. The predicted thermal cycle, power required and temperature distributions were found to be in good agreement with the experimental results. The heat generation per mm length of weld and peak temperature were found to be directly proportional to rotational speed and inversely proportional to welding speed. The rate of increase in heat generation per mm length of the weld and peak temperature are found to be higher at lower rotational speeds and lower at higher rotational speed. The heat generation during friction stir welding was found to be 80.8 % at shoulder, 16.1 % at pin side and 3.1 % at the bottom of the pin.

  6. Temporal Effects of Environmental Characteristics on Urban Air Temperature: The Influence of the Sky View Factor

    Directory of Open Access Journals (Sweden)

    Jaehyun Ha

    2016-09-01

    Full Text Available This study examines the relationship between air temperature and urban environment indices, mainly focusing on sky view factor (SVF in Seoul, Korea. We use air temperature data observed from 295 automatic weather stations (AWS during the day and night in Seoul. We conduct a spatial regression analysis to capture the effect of spatial autocorrelation in our data and identify changes in the effects of SVF on air temperature, while conducting the regression model for each dataset according to the floor area ratio (FAR. The findings of our study indicate that SVF negatively affects air temperature during both day and night when other effects are controlled through spatial regression models. Moreover, we address the environmental indices associated with day-time and night-time air temperatures and identify the changing effects of SVF on air temperature according to the areal floor area ratio of the analysis datasets. This study contributes to the literature on the relationship between SVF and air temperature in high-density cities and suggests policy implications for improving urban thermal environments with regard to urban design and planning.

  7. Temperature dependence of the calibration factor of radon and radium determination in water samples by SSNTD

    CERN Document Server

    Hunyadi, I; Hakl, J; Baradacs, E; Dezso, Z

    1999-01-01

    The sensitivity of a sup 2 sup 2 sup 6 Ra determination method of water samples by SSNTD was measured as a function of storage temperature during exposure. The method is based on an etched track type radon monitor, which is closed into a gas permeable foil and is immersed in the water sample. The sample is sealed in a glass vessel and stored for an exposure time of 10-30 days. The sensitivity increased more than a factor of two when the storage temperature was raised from 2 deg. C to 30 deg. C. Temperature dependence of the partition coefficient of radon between water and air provides explanation for this dependence. For practical radio- analytical application the temperature dependence of the calibration factor is given by fitting the sensitivity data obtained by measuring sup 2 sup 2 sup 6 Ra standard solutions (in the activity concentration range of 0.1-48.5 kBq m sup - sup 3) at different storage temperatures.

  8. Upper mantle temperatures from teleseismic tomography of French Massif Central including effects of composition, mineral reactions, anharmonicity, anelasticity and partial melt

    Science.gov (United States)

    Sobolev, Stephan V.; Zeyen, Hermann; Stoll, Gerald; Werling, Friederike; Altherr, Rainer; Fuchs, Karl

    1996-03-01

    A new technique for interpretation of 3-D seismic tomographic models in terms of temperature, degree of partial melt and rock composition is presented and tested. We consider both anharmonic and anelastic temperature effects on seismic velocities as well as the effects of mineral reactions, composition and partial melt. It is shown that composition effect is small (less than 1% of velocity) if there are no strongly depleted, Mg-rich harzburgites. We calculate anharmonic temperature derivatives of seismic velocities from compositions of mantle xenoliths. The parameters of a non-linear frequency and temperature-dependent model of attenuation have been taken from published laboratory experiments and calibrated using global Q observations in the upper mantle. For every block of the tomographic model we calculate the absolute temperature and melt fraction required to fit the observed Vp perturbation, the average temperature of the tomographic layer being constrained by the observed surface heat flow. With these temperatures we calculate attenuation, density, Vp and Vs from petrophysical modelling, using the average for 80 mantle xenoliths samples from the French Massif Central. The technique is applied to a recently published 3-D teleseismic P wave tomographic model of the upper mantle beneath the French Massif Central. The observed velocity perturbations are probably caused there by variations in temperature. Temperature does not reach the dry solidus temperature (except for a few tomographic blocks), although it comes close to it at the depth of 60-100 km below volcanic areas. At high subsolidus temperatures the contribution of anelasticity to velocity perturbations is at least as important as the combined effect of anharmonicity and mineral reactions. Our model is consistent with the Pn velocities from refraction seismic studies, QS estimations from surface waves, observed gravity, geoid, topography and surface heat flow, as well as with the composition and

  9. Impact on total population health and societal cost-effectiveness of including tumour necrosis factor- antagonists in management of ankylosing spondylitis: a dynamic population modelling study

    NARCIS (Netherlands)

    A. Tran-Duy (An); A. Boonen (Annelies); M.A.F.J. van de Laar (Martin); J.L. Severens (Hans)

    2015-01-01

    markdownabstractAbstract Background: Sequential treatment of ankylosing spondylitis (AS) that includes tumour necrosis factor-α antagonists (anti-TNF agents) has been applied in most of the Western countries. Existing cost-effectiveness (CE) models almost exclusively presented the incremental

  10. Temperature affects insulin-like growth factor I and growth of juvenile southern flounder, Paralichthys lethostigma.

    Science.gov (United States)

    Luckenbach, J Adam; Murashige, Ryan; Daniels, Harry V; Godwin, John; Borski, Russell J

    2007-01-01

    Temperature profoundly influences growth of heterothermic vertebrates. However, few studies have investigated the effects of temperature on growth and insulin-like growth factor I (IGF-I) in fishes. The aim of this study was to examine effects of temperature on growth and establish whether IGF-I may mediate growth at different temperatures in southern flounder, Paralichthys lethostigma. In two experiments, juvenile flounder were reared at 23 and 28 degrees C and growth was monitored for either 117 or 197 days. Growth was similar across treatments in both experiments until fish reached approximately 100 mm total length. Body size then diverged with fish at 23 degrees C ultimately growing 65-83% larger than those at 28 degrees C. Muscle IGF-I mRNA, plasma IGF-I, and hepatosomatic index (HSI) were significantly higher in flounder at 23 degrees C, whereas hepatic IGF-I mRNA abundance did not differ with treatment. Muscle IGF-I mRNA was correlated with HSI, while plasma IGF-I was correlated with body size, hepatic IGF-I mRNA, and HSI. These results demonstrate a strong effect of temperature on flounder growth and show that temperature-induced variation in growth is associated with differences in systemic IGF-I and local (i.e., muscle) IGF-I mRNA levels. The results also support the use of plasma IGF-I and HSI as indicators of flounder growth status.

  11. Gas-phase and Ar-matrix SQM scaling factors for various DFT functionals with basis sets including polarization and diffuse functions.

    Science.gov (United States)

    Fábri, Csaba; Szidarovszky, Tamás; Magyarfalvi, Gábor; Tarczay, György

    2011-05-12

    Scaling factors for Pulay's scaled quantum mechanical (SQM) scheme have been determined for four different widely used DFT functionals (PBE, B3LYP, B3PW91, and M06-2X) and for two basis sets (6-31++G** and aug-cc-pVTZ) by fitting computed results to 347 fundamental experimental vibrational frequencies of 33 molecules. Measurements in the gas phase and in solid argon matrices were used independently in the fitting procedure in order to provide a simple method of estimating matrix shifts. The accuracy of the new scaling factors is demonstrated on test molecules including hydrogen-bonded systems and molecules containing chlorine and sulfur atoms.

  12. Microelectromechanical System (MEMS) Gyroscope Noise Analysis and Scale Factor Characterization over Temperature Variation

    Science.gov (United States)

    2016-07-01

    bias sensitivity indicate that by multiplying the sensitivity coefficient by the current measured temperature, then subtracting that voltage value ...actual scale factors measured are slightly below the manufacturer’s nominal value of 0.012 V/°/s.) Approved for public release; distribution is...deviation value when tau was 3600 s, or 1 h. The results for both trials are presented in Table 3. Table 3 Rate random walk (°/h3/2) calculated using

  13. Determination of the rotational population of H2 and D2 including high-N states in low temperature plasmas via the Fulcher-α transition

    Science.gov (United States)

    Briefi, S.; Rauner, D.; Fantz, U.

    2017-01-01

    Vibrational and rotational excitation of the hydrogen molecule can significantly affect molecular reaction rates in low pressure low temperature plasmas, for example for the creation of H- /D- ions via the dissociative attachment process. In general, the rotational population in these discharges is known to be non-thermal with an overpopulation of states with high rotational quantum number N. In contrast to a sophisticated direct measurement of the rotational distribution in the X g+1 Σ, v = 0 state, it is demonstrated that the determination can also be carried out up to high-N levels rather easily via optical emission spectroscopy utilizing the Fulcher-α transition of H2 and D2. The measured rotational populations can be described with a two-temperature distribution where the cold part reflects the population according to the gas temperature of the discharge. This has been verified by using the emission of the second positive system of nitrogen as independent gas temperature diagnostic. The hot part where the rotational temperature reaches several thousand Kelvin arises most probably from recombinative desorption of hydrogen at the discharge vessel wall where parts of the binding energy are converted into rotational excitation. Neglecting the hot population - what is often done when using the Fulcher-α transition as gas temperature diagnostic - can lead to a strong overestimation of Tgas. No fundamental differences in the rotational distributions between hydrogen and deuterium have been found, only the hot rotational temperature is smaller for D2 indicating an isotope-dependency of the recombinative desorption process.

  14. Using an artificial neural network to predict carbon dioxide compressibility factor at high pressure and temperature

    Energy Technology Data Exchange (ETDEWEB)

    Mohagheghian, Erfan [Memorial University of Newfoundland, St. John' s (Canada); Zafarian-Rigaki, Habiballah; Motamedi-Ghahfarrokhi, Yaser; Hemmati-Sarapardeh, Abdolhossein [Amirkabir University of Technology, Tehran (Iran, Islamic Republic of)

    2015-10-15

    Carbon dioxide injection, which is widely used as an enhanced oil recovery (EOR) method, has the potential of being coupled with CO{sub 2} sequestration and reducing the emission of greenhouse gas. Hence, knowing the compressibility factor of carbon dioxide is of a vital significance. Compressibility factor (Z-factor) is traditionally measured through time consuming, expensive and cumbersome experiments. Hence, developing a fast, robust and accurate model for its estimation is necessary. In this study, a new reliable model on the basis of feed forward artificial neural networks is presented to predict CO{sub 2} compressibility factor. Reduced temperature and pressure were selected as the input parameters of the proposed model. To evaluate and compare the results of the developed model with pre-existing models, both statistical and graphical error analyses were employed. The results indicated that the proposed model is more reliable and accurate compared to pre-existing models in a wide range of temperature (up to 1,273.15 K) and pressure (up to 140MPa). Furthermore, by employing the relevancy factor, the effect of pressure and temprature on the Z-factor of CO{sub 2} was compared for below and above the critical pressure of CO{sub 2}, and the physcially expected trends were observed. Finally, to identify the probable outliers and applicability domain of the proposed ANN model, both numerical and graphical techniques based on Leverage approach were performed. The results illustrated that only 1.75% of the experimental data points were located out of the applicability domain of the proposed model. As a result, the developed model is reliable for the prediction of CO{sub 2} compressibility factor.

  15. Numerical Analysis of Influencing Factors on Temperature Field and Airflow Distribution of the Displacement Ventilation System

    Institute of Scientific and Technical Information of China (English)

    NA Yanling; XING Jincheng; TU Guangbei; YU Songbo

    2005-01-01

    Indoor air quality and thermal comfort are important features of indoor environment. In this paper, a numerical simulation based on the k-ε model of CFD is used to analyze factors such as loading, exterior-protected construction, blowing-in rate that play an important role in the temperature field and airflow field of the displacement ventilation system. Exterior-protected construction has little influence on indoor temperature distribution of displacement ventilation systems and the influence is limited only in a small area near the external wall when the indoor heat source is the main cooling load.The height of a room has little influence on indoor temperature field, and the temperature gradient of active region is basically unchanged. In the system combined with a displacement ventilation system and a cooling system, the height also has little influence. When the cooling load is high,the indoor heat source creates a strong convective plume, which will make the average indoor air age lower, the ventilation efficiency higher and the elimination of pollutant easier. Air supply rate plays an important role in displacement ventilation systems. The increase of air supply rate that can be realized by increasing the air supply velocity and enlarging the area of air inlet will increase the mass capability of the system and diminish the vertical temperature gradient. From the comparison between simulations and experiments, it is concluded that this simulation are creditable.

  16. Provide a suitable range to include the thermal creeping effect on slip velocity and temperature jump of an air flow in a nanochannel by lattice Boltzmann method

    Science.gov (United States)

    Karimipour, Arash

    2017-01-01

    The thermal creeping effect on slip velocity of air forced convection through a nanochannel is studied for the first time by using a lattice Boltzmann method. The nanochannel side walls are kept hot while the cold inlet air streams along them. The computations are presented for the wide range of Reynolds number, Knudsen number and Eckert number while slip velocity and temperature jump effects are involved. Moreover appropriate validations are performed versus previous works concerned the micro-nanoflows. The achieved results are shown as the velocity and temperature profiles at different cross sections, streamlines and isotherms and also the values of slip velocity and temperature jump along the nanochannel walls. The ability of the lattice Boltzmann method to simulate the thermal creeping effects on hydrodynamic and thermal domains of flow is shown at this study; so that its effects should be involved at lower values of Eckert number and higher values of Reynolds number especially at entrance region where the most temperature gradient exists.

  17. Quantifying the influences of various ecological factors on land surface temperature of urban forests.

    Science.gov (United States)

    Ren, Yin; Deng, Lu-Ying; Zuo, Shu-Di; Song, Xiao-Dong; Liao, Yi-Lan; Xu, Cheng-Dong; Chen, Qi; Hua, Li-Zhong; Li, Zheng-Wei

    2016-09-01

    Identifying factors that influence the land surface temperature (LST) of urban forests can help improve simulations and predictions of spatial patterns of urban cool islands. This requires a quantitative analytical method that combines spatial statistical analysis with multi-source observational data. The purpose of this study was to reveal how human activities and ecological factors jointly influence LST in clustering regions (hot or cool spots) of urban forests. Using Xiamen City, China from 1996 to 2006 as a case study, we explored the interactions between human activities and ecological factors, as well as their influences on urban forest LST. Population density was selected as a proxy for human activity. We integrated multi-source data (forest inventory, digital elevation models (DEM), population, and remote sensing imagery) to develop a database on a unified urban scale. The driving mechanism of urban forest LST was revealed through a combination of multi-source spatial data and spatial statistical analysis of clustering regions. The results showed that the main factors contributing to urban forest LST were dominant tree species and elevation. The interactions between human activity and specific ecological factors linearly or nonlinearly increased LST in urban forests. Strong interactions between elevation and dominant species were generally observed and were prevalent in either hot or cold spots areas in different years. In conclusion, quantitative studies based on spatial statistics and GeogDetector models should be conducted in urban areas to reveal interactions between human activities, ecological factors, and LST.

  18. Factors affecting the wettability of different surface materials with vegetable oil at high temperatures and its relation to cleanability

    Energy Technology Data Exchange (ETDEWEB)

    Ashokkumar, Saranya, E-mail: saras@food.dtu.dk [Accoat A/S, Munkegardsvej 16, 3490 Kvistgard (Denmark); Food Production Engineering, DTU FOOD, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Adler-Nissen, Jens [Food Production Engineering, DTU FOOD, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Moller, Per [Department of Materials Science and Engineering, DTU Mechanical Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark)

    2012-12-15

    Graphical abstract: Plot of cos {theta} versus temperature for metal and ceramic surfaces where cos {theta} rises linearly with increase in temperature. Highlights: Black-Right-Pointing-Pointer cos {theta} of olive oil on different surface materials rises linearly with increase in temperature. Black-Right-Pointing-Pointer Slopes are much higher for quasicrystalline and polymers than for ceramics. Black-Right-Pointing-Pointer Increase in surface roughness and surface flaws increases surface wettability. Black-Right-Pointing-Pointer Contact angle values gave information for grouping easy-clean polymers from other materials. Black-Right-Pointing-Pointer Contact angle measurements cannot directly estimate the cleanability of a surface. - Abstract: The main aim of the work was to investigate the wettability of different surface materials with vegetable oil (olive oil) over the temperature range of 25-200 Degree-Sign C to understand the differences in cleanability of different surfaces exposed to high temperatures in food processes. The different surface materials investigated include stainless steel (reference), PTFE (polytetrafluoroethylene), silicone, quasicrystalline (Al, Fe, Cr) and ceramic coatings: zirconium oxide (ZrO{sub 2}), zirconium nitride (ZrN) and titanium aluminum nitride (TiAlN). The ceramic coatings were deposited on stainless steel with two different levels of roughness. The cosine of the contact angle of olive oil on different surface materials rises linearly with increasing temperature. Among the materials analyzed, polymers (PTFE, silicone) gave the lowest cos {theta} values. Studies of the effect of roughness and surface flaws on wettability revealed that the cos {theta} values increases with increasing roughness and surface flaws. Correlation analysis indicates that the measured contact angle values gave useful information for grouping easy-clean polymer materials from the other materials; for the latter group, there is no direct relation between

  19. [Structural analysis for psychosocial factors including health locus of control (HLC) and sense of coherence (SOC) associated with lifestyle-related diseases].

    Science.gov (United States)

    Ogawa, Y; Nakamura, H; Nagase, H; Ogino, K; Ooshita, Y; Tsukahara, S

    2001-01-01

    The purpose of this study was to clarify psychosocial characteristics associated with preventive health behavior for lifestyle-related diseases. The author performed objective health examinations and gave questionnaires to 289 men (39.7 +/- 11.8 years, mean +/- SD) and 80 women (32.8 +/- 10.4 years) engaged in office work. Psychosocial factors included lifestyle and perceived stress, as well as the health locus of control (HLC) and sense of coherence (SOC) as newly developed indicators for health behavior. The principal component analysis for men did not extract lifestyle from the psychosocial structures. Multiple regression analysis showed that internal HLC (IHLC), chance HLC (CHLC), professional HLC (PHLC) and stress significantly contributed to SOC. Principal component analysis using psychosocial factors in women showed two psychosocial structures, i.e. the second principal (high SOC, high lifestyle, and low stress) and the 4th principal components (high supernatural HLC, and high PHLC). Both components were negatively correlated with systolic blood pressure. SOC was recognized to be negatively associated with age, stress, and total cholesterol, and positively with IHLC, FHLC, lifestyle, and gamma-GTP using multiple regression analysis for women. These results indicated a distinguishable sex difference regarding the involvement of psychosocial factors including HLC and SOC in objective health. SOC seems likely to be involved not in objective health, but closely with stress, suggesting a direct influence on mental health. Lifestyle should be divided into more detailed categories such as smoking and salt intake. Structural analysis of women suggests that SOC is involved directly or indirectly through lifestyle in objective health, different from men. To further clarify causal relationships between psychosocial factors and risk factors for lifestyle-related diseases, a longitudinal study is necessary based on these results.

  20. Escape factors for Paschen 2p-1s emission lines in low-temperature Ar, Kr, and Xe plasmas

    Science.gov (United States)

    Zhu, Xi-Ming; Cheng, Zhi-Wen; Pu, Yi-Kang; Czarnetzki, Uwe

    2016-06-01

    Radiation trapping phenomenon is often observed when investigating low-temperature plasmas. Photons emitted from the upper excited states may be reabsorbed by the lower states before they leave the plasmas. In order to account for this effect in the modelling and optical diagnostics of plasmas, either an ‘escape factor’ of a function of the optical depth or a strict solution of the radiation transfer equation can be employed. However, the former is more convenient in comparison and thus is widely adopted. Previous literatures have provided several simple expressions of the escape factor for the uniform plasmas. The emission line profiles are assumed to be dominated by the Doppler broadening, and the line splitting due to the hyperfine structure is not considered. This kind of expression is only valid for small atoms, e.g. Ar in low-pressure uniform discharges. Actually, the excited state density in many of the low-temperature plasmas is non-uniform and the emission line profile can be significantly influenced by the collisional broadening at medium and high pressures. In these cases, a new escape factor equation should be calculated. In this work, we study the escape factor equations for the often used 2p-1s transitions (Paschen’s notation) of the Ar, Kr, and Xe atoms. Possible non-uniform density profiles are considered. In addition, we include the line splitting due to the hyperfine structure for Kr and Xe. For the low-pressure plasmas, an escape factor expression mainly based on the Gaussian line profile is given and particularly verified by an experiment in a low-pressure capacitive discharge. For the high-pressure plasmas, an equation based on the Voigt line profile is also calculated. In this way, the new escape factor expression is ready for use in the modelling of the Ar, Kr, and Xe plasmas from low to atmospheric pressure.

  1. Long-term global temperature variations under the influence of different cosmophysical factors

    Science.gov (United States)

    Biktash, Lilia

    2016-07-01

    We have analyzed different cosmophysical factors which have effect on long-term global temperature variations during solar cycles 20-24. A detailed analysis of total solar irradiance (TSI), the spectral solar ultraviolet emission (UV), space weather and cosmic rays (CRs) have effects on the atmosphere processes. We have shown that increasing of global temperature is likely affected by TSI and UV during solar maxima. During the descending phases of these solar cycles the interplanetary magnetic field and long-lasting solar wind high speed streams occurred frequently and were the primary contributors to minimize of CRs effect on the Earth's atmosphere. In this case global temperature is increased extra as result of increase in the atmosphere's transparency. We show that there are a few effective physical mechanisms of the action of solar activity and space weather on the global temperature. TSI and CRs play essential role in climate change and main part of climate variations can be explained by the mechanism of action TSI and CRs modulated by the solar activity on the state of lower atmosphere and meteorological parameters.

  2. batman Interacts with polycomb and trithorax group genes and encodes a BTB/POZ protein that is included in a complex containing GAGA factor.

    Science.gov (United States)

    Faucheux, M; Roignant, J-Y; Netter, S; Charollais, J; Antoniewski, C; Théodore, L

    2003-02-01

    Polycomb and trithorax group genes maintain the appropriate repressed or activated state of homeotic gene expression throughout Drosophila melanogaster development. We have previously identified the batman gene as a Polycomb group candidate since its function is necessary for the repression of Sex combs reduced. However, our present genetic analysis indicates functions of batman in both activation and repression of homeotic genes. The 127-amino-acid Batman protein is almost reduced to a BTB/POZ domain, an evolutionary conserved protein-protein interaction domain found in a large protein family. We show that this domain is involved in the interaction between Batman and the DNA binding GAGA factor encoded by the Trithorax-like gene. The GAGA factor and Batman codistribute on polytene chromosomes, coimmunoprecipitate from nuclear embryonic and larval extracts, and interact in the yeast two-hybrid assay. Batman, together with the GAGA factor, binds to MHS-70, a 70-bp fragment of the bithoraxoid Polycomb response element. This binding, like that of the GAGA factor, requires the presence of d(GA)n sequences. Together, our results suggest that batman belongs to a subset of the Polycomb/trithorax group of genes that includes Trithorax-like, whose products are involved in both activation and repression of homeotic genes.

  3. Real-time monitoring of radiofrequency ablation of liver tumors using thermal-dose calculation by MR temperature imaging: initial results in nine patients, including follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Lepetit-Coiffe, Matthieu; Quesson, Bruno; Moonen, Chrit T.W. [Universite Victor Segalen Bordeaux 2, Laboratoire Imagerie Moleculaire et Fonctionnelle: de la physiologie a la therapie CNRS UMR 5231, Bordeaux Cedex (France); Laumonier, Herve; Trillaud, Herve [Universite Victor Segalen Bordeaux 2, Laboratoire Imagerie Moleculaire et Fonctionnelle: de la physiologie a la therapie CNRS UMR 5231, Bordeaux Cedex (France); Service de Radiologie, Hopital Saint-Andre, CHU Bordeaux, Bordeaux (France); Seror, Olivier [Universite Victor Segalen Bordeaux 2, Laboratoire Imagerie Moleculaire et Fonctionnelle: de la physiologie a la therapie CNRS UMR 5231, Bordeaux Cedex (France); Service de Radiologie, Hopital Jean Verdier, Bondy (France); Sesay, Musa-Bahazid [Service d' Anesthesie Reanimation III, Hopital Pellegrin, CHU Bordeaux, Bordeaux (France); Grenier, Nicolas [Universite Victor Segalen Bordeaux 2, Laboratoire Imagerie Moleculaire et Fonctionnelle: de la physiologie a la therapie CNRS UMR 5231, Bordeaux Cedex (France); Service d' Imagerie Diagnostique et Therapeutique de l' Adulte, Hopital Pellegrin, CHU Bordeaux, Bordeaux (France)

    2010-01-15

    To assess the practical feasibility and effectiveness of real-time magnetic resonance (MR) temperature monitoring for the radiofrequency (RF) ablation of liver tumours in a clinical setting, nine patients (aged 49-87 years, five men and four women) with one malignant tumour (14-50 mm, eight hepatocellular carcinomas and one colorectal metastasis), were treated by 12-min RF ablation using a 1.5-T closed magnet for real-time temperature monitoring. The clinical monopolar RF device was filtered at 64 MHz to avoid electromagnetic interference. Real-time computation of thermal-dose (TD) maps, based on Sapareto and Dewey's equation, was studied to determine its ability to provide a clear end-point of the RF procedure. Absence of local recurrence on follow-up MR images obtained 45 days after the RF ablation was used to assess the apoptotic and necrotic prediction obtained by real-time TD maps. Seven out of nine tumours were completely ablated according to the real-time TD maps. Compared with 45-day follow-up MR images, TD maps accurately predicted two primary treatment failures, but were not relevant in the later progression of one case of secondary local tumour. The real-time TD concept is a feasible and promising monitoring method for the RF ablation of liver tumours. (orig.)

  4. Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography

    Science.gov (United States)

    Kim, Hye-Geum; Kong, Eun-Jung; Cheon, Eun-Jin; Kim, Hae-Won; Koo, Bon-Hoon

    2016-01-01

    The purpose of this study was to explore the relationship between cerebral amyloid deposition and overall clinical factors including cognitive functions in geriatric depression by using 18F-florbetaben positron emission tomography. Thirteen subjects aged over 60 years who had a history of major depressive disorder and also had subjective memory complaint were included. Of all subjects, 3 subjects judged as amyloid positive, and the others judged as amyloid negative. Their memory, visuospatial functions and attention abilities were negatively correlated with amyloid deposition in specific brain regions, but their language and recognition abilities were not correlated with any region. The amyloid deposition of the whole brain region was significantly negatively correlated with immediate memory. PMID:27776391

  5. Factors controlling cloud microphysics, precipitation rate, and brightness temperature of tropical convective and stratiform clouds

    Science.gov (United States)

    Hashino, T.; Casella, D.; Mugnai, A.; Sano, P.; Smith, E. A.; Tripoli, G.

    2008-12-01

    This paper discusses factors controlling cloud microphysics, precipitation rate and brightness temperature of tropical convective and stratiform clouds. Tropical convective and stratiform clouds are important in radiative forcing of climates and distribution of precipitation over the ocean. The possible effects of climate change on these clouds are still not well understood. Recent studies show that the higher CCN concentration in a convective cloud can lead to more vigorous updrafts and a higher evaporation/precipitation ratio. The stronger updraft often means stronger downdraft and gust fronts, which can trigger convection nearby. This implies that increases in CCN concentration can result in an increase in area coverage and persistence of tropical cirrus and stratiform clouds. The increased cloudiness would then be expected to lower sensible and latent heat flux from the ocean by lowering sea surface temperature, affecting the future development of convective clouds. The sea surface temperature may also change in a local area due to change of ocean circulation in climate change scenarios. Satellite remote sensing is a powerful tool to study tropical and global precipitation distribution. Many physically-based passive-microwave (MW) satellite precipitation algorithms make use of cloud radiation databases (CRDs), which typically consist of microphysical profiles from cloud resolving model (CRMs) and simulated MW brightness temperature (Tb). Thus, it is important to validate Tb simulated by a CRM against the observed Tb. Also, it is important to study how any changes in the tropical clouds due to aerosols and sea surface temperature translate into the precipitation and brightness temperature. The case study chosen is KWAJEX campaign that took place from 23 July to 14 September 1999. Authors have developed microphysical physical framework (Advanced Microphysics Prediction System) to predict ice particle properties explicitly in a CRM (University of Wisconsin

  6. Is there a need to include HIV, HBV and HCV viruses in the Saudi premarital screening program on the basis of their prevalence and transmission risk factors?

    Science.gov (United States)

    Alswaidi, F M; O'Brien, S J

    2010-11-01

    In January 2008, the Saudi Arabian health authority included mandatory testing for HIV, HBV and HCV viruses in the premarital screening program. Epidemiologically, there were few justifications for their inclusion as disease prevalences and distributions are poorly understood in the population. This study aims to provide information about HBV, HCV and HIV prevalences and risk factors for disease transmission and so produce evidence for informed decision-making on the inclusion of these infectious diseases in the screening program. This is a cross-sectional descriptive study embedded in the existing national premarital screening program for thalassaemia and sickle cell disease to estimate the prevalence of HIV, HBV and HCV infections (n=74,662 individuals), followed by a case-control study to identify risk factors responsible for infection transmission (n=540). The average HIV prevalence is 0.03%, 1.31% for HBV and 0.33% for HCV. Sharing personal belongings particularly razors, blood transfusions, cuts at barbershops and extramarital relationships showed the highest significant associations with the transmission of these viruses. The prevalences of HIV, HBV and HCV in Saudi Arabia are among the lowest worldwide. However, all the important risk factors associated with transmitting these viruses are significantly present in the Saudi community. Saudi Arabia is financially capable of screening for these infections in the mandatory premarital program and of providing medical care for the discovered cases, but focusing on the health education programs may offset the need to mandatory testing.

  7. Evaluation of the spatial patterns and risk factors, including backyard pigs, for classical swine fever occurrence in Bulgaria using a Bayesian model

    Directory of Open Access Journals (Sweden)

    Beatriz Martínez-López

    2014-05-01

    Full Text Available The spatial pattern and epidemiology of backyard pig farming and other low bio-security pig production systems and their role in the occurrence of classical swine fever (CSF is described and evaluated. A spatial Bayesian model was used to explore the risk factors, including human demographics, socioeconomic and environmental factors. The analyses were performed for Bulgaria, which has a large number of backyard farms (96% of all pig farms in the country are classified as backyard farms, and it is one of the countries for which both backyard pig and farm counts were available. Results reveal that the high-risk areas are typically concentrated in areas with small family farms, high numbers of outgoing pig shipments and low levels of personal consumption (i.e. economically deprived areas. Identification of risk factors and high-risk areas for CSF will allow to targeting risk-based surveillance strategies leading to prevention, control and, ultimately, elimination of the disease in Bulgaria and other countries with similar socio-epidemiological conditions.

  8. Temperature and moisture conditions for life in the extreme arid region of the Atacama desert: four years of observations including the El Nino of 1997-1998

    Science.gov (United States)

    McKay, Christopher P.; Friedmann, E. Imre; Gomez-Silva, Benito; Caceres-Villanueva, Luis; Andersen, Dale T.; Landheim, Ragnhild

    2003-01-01

    The Atacama along the Pacific Coast of Chile and Peru is one of the driest and possibly oldest deserts in the world. It represents an extreme habitat for life on Earth and is an analog for life in dry conditions on Mars. We report on four years (September 1994-October 1998) of climate and moisture data from the extreme arid region of the Atacama. Our data are focused on understanding moisture sources and their role in creating suitable environments for photosynthetic microorganisms in the desert surface. The average air temperature was 16.5 degrees C and 16.6 degrees C in 1995 and 1996, respectively. The maximum air temperature recorded was 37.9 degrees C, and the minimum was -5.7 degrees C. Annual average sunlight was 336 and 335 W m(-2) in 1995 and 1996, respectively. Winds averaged a few meters per second, with strong fohn winds coming from the west exceeding 12 m s(-1). During our 4 years of observation there was only one significant rain event of 2.3 mm, which occurred near midnight local time. We suggest that this event was a rainout of a heavy fog. It is of interest that the strong El Nino of 1997-1998 brought heavy rainfall to the deserts of Peru, but did not bring significant rain to the central Atacama in Chile. Dew occurred at our station frequently following high nighttime relative humidity, but is not a significant source of moisture in the soil or under stones. Groundwater also does not contribute to surface moisture. Only the one rain event of 2.3 mm resulted in liquid water in the soil and beneath stones for a total of only 65-85 h over 4 years. The paucity of liquid water under stones is consistent with the apparent absence of hypolithic (under-stone) cyanobacteria, the only known primary producers in such extreme deserts.

  9. A STUDY OF CHINESE YUAN (RMB APPRECIATION ACCOMPANYING WITH OTHERS FACTORS INCLUDING FOREIGN DIRECT INVESTMENT (FDI AND THEIR EFFECT ON CHINA ECONOMY

    Directory of Open Access Journals (Sweden)

    Ping-fu (Brian LAI

    2014-07-01

    Full Text Available The Chinese Yuan (RMB has been on the trend of appreciation over the last decade, and such a trend will likely be continuing for some years over the next decade. According to some scholars in their published literatures, the appreciation of RMB, the influx of Foreign Direct Investment (FDI has been ongoing accompanying the sustained growing economy in mainland China over the past decade. It is believed that the China economy has an implication from some significant factors including appreciation of RMB, interest rate of RMB, inflation and continuous increase of FDI for the next several years. The present study aims to provide an emphasis on investigation into effect on China economy as a result of appreciation of RMB and FDI together with some other factors, and to provide an outlook on the economy in China for the coming decades. First, a review was carried on relevant background information and development history of RMB and FDI. There are many reasons and factors behind leading to the sustained growth in the economy in China in the last decade and such effects were in coverage in the literature review. An overview of the development of RMB exchange mechanism, and other variables including (1 RMB exchange rate, (2 China interest rate, (3 Foreign Direct Investment (FDI, (4 Trade Balance of China, (5 Annual Inflation rate in China, (6 Energy Consumption in China, (7 Foreign Exchange Reserve in China, (8 China wages, (9 China External Debt and (10 China Consumer Price Index, which may have effect on the growth of the economy in China is covered in the literature review conducted in Chapter 2.

  10. Surface air temperature changes from 1909 to 2008 in Southeast Asia assessed by factor analysis

    Science.gov (United States)

    Chooprateep, Suree; McNeil, Nittaya

    2016-01-01

    Monthly seasonally adjusted surface temperature patterns in Southeast Asia from 1909 to 2008 were studied. The area comprised 40 regions of 10° × 10° grid boxes in latitudes 25°S to 25°N and longitudes 75°E to 160°E. Temperatures were studied for three overlapping 36-year periods, the first period 1909-1944, the second period 1941-1976 and the third period 1973-2008. The data of each 36-year period were fitted to reduce autocorrelations at lags 1 and 2 months. Factor analysis was used to account for spatial correlation between grid boxes giving six contiguous layer regions. Simple linear regression models were fitted to data within these larger regions. Temperatures were found to have increased in five from six regions over the first period with the increases ranging from 0.005 to 0.148 °C per decade, in only three regions over the second period with the increases ranging from 0.008 to 0.150 °C per decade and in six regions over the third period with the increases ranging from 0.082 to 0.222 °C per decade.

  11. Correlations among factors of sulfide ores in oxidation process at ambient temperature

    Institute of Scientific and Technical Information of China (English)

    吴超; 李孜军; 周勃

    2004-01-01

    Spontaneous combustion is one of the serious problems in the mining of sulfide ore deposits. The relevant factors, e. G. Oxygen absorption quantity, mass increase, contents of water soluble iron ions and sulfate ion of sulfide ore samples in the oxidation process were investigated both in theory and experiment. The results from the investigation show that there is no general interpretation relation among the oxygen absorption quantity, the contents of sulfate ion and water soluble iron ions during the oxidation process of sulfide ores at ambient temperature.However, there is a linear relationship between the mass increase of the sulfide ore samples in the oxidation process at ambient temperature and the quantity of oxygen absorption. Therefore, the simple and cheap mass scaling method is suitable for predicting the oxygen absorption performance of sulfide ores at ambient temperature in place of the expensive and complicated chemical method used hitherto. Furthermore, combined with other items of breeding-fire test, the mass increase potential can also be used to predict the spontaneous combustion tendency of sulfide ores.

  12. Study Modules for Calculus-Based General Physics. [Includes Modules 18-20: Sound; Temperature, Heat, and Thermodynamics: First Law; and Kinetic Theory of Gases].

    Science.gov (United States)

    Fuller, Robert G., Ed.; And Others

    This is part of a series of 42 Calculus Based Physics (CBP) modules totaling about 1,000 pages. The modules include study guides, practice tests, and mastery tests for a full-year individualized course in calculus-based physics based on the Personalized System of Instruction (PSI). The units are not intended to be used without outside materials;…

  13. EFFECTS OF NEUTRINO ELECTROMAGNETIC FORM FACTORS ON NEUTRINO INTERACTION WITH FINITE TEMPERATURE ELECTRON MATTERS

    Directory of Open Access Journals (Sweden)

    Anto Sulaksono

    2011-11-01

    Full Text Available The differential cross-section of neutrino interaction with dense and warm electron gasses has been calculated by takinginto account the neutrino electromagnetic form factors. The significant effect of electromagnetic properties of neutrinocan be found if the neutrino dipole moment, μ ν , is ≥ 5.10-9 μB and neutrino charge radius, Rv, is ≥ 5.10-6 MeV-1. Theimportance of the retarded correction, detailed balance and Pauli blocking factors is shown and analyzed. Many-bodyeffects on the target matter which are included via random phase approximation (RPA correlation as well as photoneffective mass are also investigated.

  14. UV-photodegradation of desipramine: Impact of concentration, pH and temperature on formation of products including their biodegradability and toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, Nareman D.H.; Mahmoud, Waleed M.M. [Sustainable Chemistry and Material Resources, Institute of Sustainable and Environmental Chemistry, Leuphana University of Lüneburg, Scharnhorststraße 1 C13, DE 21335 Lüneburg (Germany); Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia 41522 (Egypt); Olsson, Oliver [Sustainable Chemistry and Material Resources, Institute of Sustainable and Environmental Chemistry, Leuphana University of Lüneburg, Scharnhorststraße 1 C13, DE 21335 Lüneburg (Germany); Kümmerer, Klaus, E-mail: klaus.kuemmerer@leuphana.de [Sustainable Chemistry and Material Resources, Institute of Sustainable and Environmental Chemistry, Leuphana University of Lüneburg, Scharnhorststraße 1 C13, DE 21335 Lüneburg (Germany)

    2016-10-01

    Desipramine (DMI) is a widely used tricyclic antidepressant, and it is the major metabolite of imipramine (IMI) and lofepramine (LMI); IMI and LMI are two of the most commonly used tricyclic antidepressants. If DMI enters the aquatic environment, it can be transformed by the environmental bacteria or UV radiation. Therefore, photolysis of DMI in water was performed using a simulated sunlight Xenon-lamp and a UV-lamp. Subsequently, the biodegradability of DMI and its photo-transformation products (PTPs) formed during its UV photolysis was studied. The influence of variable conditions, such as initial DMI concentration, solution pH, and temperature, on DMI UV photolysis behavior was also studied. The degree of mineralization of DMI and its PTPs was monitored. A Shimadzu HPLC-UV apparatus was used to follow the kinetic profile of DMI during UV-irradiation; after that, ion-trap and high-resolution mass spectrometry coupled with chromatography were used to monitor and identify the possible PTPs. The environmentally relevant properties and selected toxicity properties of DMI and the non-biodegradable PTPs were predicted using different QSAR models. DMI underwent UV photolysis with first-order kinetics. Quantum yields were very low. DOC values indicated that DMI formed new PTPs and was not completely mineralized. Analysis by means of high-resolution mass spectrometry revealed that the photolysis of DMI followed three main photolysis pathways: isomerization, hydroxylation, and ring opening. The photolysis rate was inversely proportional to initial DMI concentration. The pH showed a significant impact on the photolysis rate of DMI, and on the PTPs in terms of both formation kinetics and mechanisms. Although temperature was expected to increase the photolysis rate, it showed a non-significant impact in this study. Results from biodegradation tests and QSAR analysis revealed that DMI and its PTPs are not readily biodegradable and that some PTPs may be human and/or eco

  15. Soot temperature and KL factor for biodiesel and diesel spray combustion in a constant volume combustion chamber

    KAUST Repository

    Zhang, Ji

    2013-07-01

    This paper presents measurements of the soot temperature and KL factor for biodiesel and diesel combustion in a constant volume chamber using a two-color technique. This technique uses a high-speed camera coupled with two narrowband filters (550. nm and 650. nm, 10. nm FWHM). After calibration, statistical analysis shows that the uncertainty of the two-color temperature is less than 5%, while it is about 50% for the KL factor. This technique is then applied to the spray combustion of biodiesel and diesel fuels under an ambient oxygen concentration of 21% and ambient temperatures of 800, 1000 and 1200. K. The heat release result shows higher energy utilization efficiency for biodiesel compared to diesel under all conditions; meanwhile, diesel shows a higher pressure increase due to its higher heating value. Biodiesel yields a lower temperature inside the flame area, a longer soot lift-off length, and a smaller soot area compared to diesel. Both the KL factor and the total soot with biodiesel are lower than with diesel throughout the entire combustion process, and this difference becomes larger as the ambient temperature decreases. Biodiesel shows approximately 50-100. K lower temperatures than diesel at the quasi-steady stage for 1000 and 1200. K ambient temperature, while diesel shows a lower temperature than biodiesel at 800. K ambient. This result may raise the question of how important the flame temperature is in explaining the higher NO. x emissions often observed during biodiesel combustion. Other factors may also play an important role in controlling NO. x emissions. Both biodiesel and diesel temperature measurements show a monotonic dependence on the ambient temperature. However, the ambient temperature appears to have a more significant effect on the soot formation and oxidation in diesel combustion, while biodiesel combustion soot characteristics shows relative insensitivity to the ambient temperature. © 2013 Elsevier Ltd.

  16. Mechanism and Influencing Factors of Iron Nuggets Forming in Rotary Hearth Furnace Process at Lower Temperature

    Science.gov (United States)

    Han, Hongliang; Duan, Dongping; Chen, Siming; Yuan, Peng

    2015-10-01

    In order to improve the efficiency of slag and iron separation, a new idea of "the separation of slag (solid state) and iron (molten state) in rotary hearth furnace process at lower temperature" is put forward. In this paper, the forming process of iron nuggets has been investigated. Based on those results, the forming mechanisms and influencing factors of iron nugget at low temperature are discussed experimentally using an electric resistance furnace simulating a rotary hearth furnace process. Results show that the reduction of iron ore, carburization of reduced iron, and the composition and quantity of slag are very important for producing iron nuggets at lower temperature. Reduction reaction of carbon-containing pellets is mainly at 1273 K and 1473 K (1000 °C and 1200 °C). When the temperature is above 1473 K (1200 °C), the metallization rate of carbon-containing pellets exceeds 93 pct, and the reduction reaction is substantially complete. Direct carburization is the main method for carburization of reduced iron. This reaction occurs above 1273 K (1000 °C), with carburization degree increasing greatly at 1473 K and 1573 K (1200 °C and 1300 °C) after particular holding times. Besides, to achieve the "slag (solid state) and iron (molten state) separation," the melting point of the slag phase should be increased. Slag (solid state) and iron (molten state) separation can be achieved below 1573 K (1300 °C), and when the holding time is 20 minutes, C/O is 0.7, basicity is less than 0.5 and a Na2CO3 level of 3 pct, the recovery rate of iron can reach 90 pct, with a proportion of iron nuggets more than 3.15 mm of nearly 90 pct. This study can provide theoretical and technical basis for iron nugget production.

  17. Quaternary ammonium room-temperature ionic liquid including an oxygen atom in side chain/lithium salt binary electrolytes: ab initio molecular orbital calculations of interactions between ions.

    Science.gov (United States)

    Tsuzuki, Seiji; Hayamizu, Kikuko; Seki, Shiro; Ohno, Yasutaka; Kobayashi, Yo; Miyashiro, Hajime

    2008-08-14

    Interactions of the lithium bis(trifluoromethylsulfonyl)amide (LiTFSA) complex with N, N-diethyl-N-methyl-N-(2-methoxyethyl) ammonium (DEME), 1-ethyl-3-methylimidazolium (EMIM) cations, neutral diethylether (DEE), and the DEMETFSA complex were studied by ab initio molecular orbital calculations. An interaction energy potential calculated for the DEME cation with the LiTFSA complex has a minimum when the Li atom has contact with the oxygen atom of DEME cation, while potentials for the EMIM cation with the LiTFSA complex are always repulsive. The MP2/6-311G**//HF/6-311G** level interaction energy calculated for the DEME cation with the LiTFSA complex was -18.4 kcal/mol. The interaction energy for the neutral DEE with the LiTFSA complex was larger (-21.1 kcal/mol). The interaction energy for the DEMETFSA complex with LiTFSA complex is greater (-23.2 kcal/mol). The electrostatic and induction interactions are the major source of the attraction in the two systems. The substantial attraction between the DEME cation and the LiTFSA complex suggests that the interaction between the Li cation and the oxygen atom of DEME cation plays important roles in determining the mobility of the Li cation in DEME-based room temperature ionic liquids.

  18. Prevalence study and risk factor analysis of selected bacterial, protozoal and viral, including vector-borne, pathogens in cats from Cyprus.

    Science.gov (United States)

    Attipa, Charalampos; Papasouliotis, Kostas; Solano-Gallego, Laia; Baneth, Gad; Nachum-Biala, Yaarit; Sarvani, Elpida; Knowles, Toby G; Mengi, Sena; Morris, David; Helps, Chris; Tasker, Séverine

    2017-03-13

    Feline infectious agent studies are lacking in Cyprus. The aims of this study were to determine the prevalence and risk factors for various feline infectious agents, including feline vector-borne pathogens (FVBP), in cats from Cyprus. A cross-sectional, descriptive, multicentre study was performed on 174 feline samples [138 owned and 36 shelter-feral, including both healthy (43) and non-healthy (131), cats] from private veterinary clinics from all six districts of Cyprus. Real-time quantitative polymerase chain reaction (qPCR) assays were used to detect Mycoplasma haemofelis (Mhf), "Candidatus Mycoplasma haemominutum" (CMhm) and "Candidatus Mycoplasma turicensis" (CMt). The population was tested for four FVBP including Bartonella henselae and Leishmania spp. using qPCR, while conventional PCR assays were used to detect Ehrlichia/Anaplasma spp. and Hepatozoon spp. Serological assays were performed to detect Leishmania infantum antibodies, feline leukaemia virus (FeLV) antigen and feline immunodeficiency virus (FIV) antibodies. Statistical analysis was performed to test associations and possible risk factors between variables and infectious agents. Ninety-six (55.2%) of the 174 cats were PCR-positive for at least one infectious agent. Forty-six cats (26.4%) were haemoplasma positive, including 13 (7.5%) for Mhf, 36 (20.7%) for CMhm and 12 (6.9%) for CMt. Sixty-six cats (37.9%) were positive for Hepatozoon spp., while 19 (10.9%) were positive for B. henselae, four (2.3%) for Leishmania spp. and one (0.6%) for Ehrlichia/Anaplasma spp. Sequencing revealed the presence of Hepatozoon felis, L. infantum and Anaplasma platys. Of the 164 cats that underwent retroviral serology, 10 (6.1%) were FeLV-positive and 31 (18.9%) were FIV-positive, while L. infantum serology was positive in 7 (4.4%) of the 160 cats tested. Multivariable logistic regression revealed significant associations for various infectious agents including L. infantum with each of Hepatozoon spp. and CMt

  19. Study on the social maturity, self-perception, and associated factors, including motor coordination, of children with attention deficit hyperactivity disorder.

    Science.gov (United States)

    Kaneko, Fumiko; Okamura, Hitoshi

    2005-01-01

    This study was designed to identify characteristics of social maturity and self-perception in children with attention deficit hyperactivity disorder (ADHD) and to elucidate associated factors, including motor coordination. The subjects were 15 children (14 boys and 1 girl, in elementary school grades 3 to 6). Their characteristics were assessed with the Movement Assessment Battery for Children (M-ABC), the Japanese version of the Social Maturity Scale-R (S-M scale), and Harter's Self Perception Profile for Children (SPPC). The results of the study suggested that most of the subjects had some degree of motor problem and delay of social maturity. They also suggested an association between social maturity and static-dynamic balance, which was one of the indices of motor coordination.

  20. Risk factors for bloodstream infection caused by extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: A focus on antimicrobials including cefepime.

    Science.gov (United States)

    Chopra, Teena; Marchaim, Dror; Johnson, Paul C; Chalana, Indu K; Tamam, Zeinab; Mohammed, Mazin; Alkatib, Shatha; Tansek, Ryan; Chaudhry, Khawar; Zhao, Jing J; Pogue, Jason M; Kaye, Keith S

    2015-07-01

    Extended-spectrum β-lactamase (ESBL)-producing pathogens represent increasing challenges to physicians because of rising prevalence, high mortality, and challenging treatment. Identifying high risks and early appropriate therapy is critical to favorable outcomes. This is a 5-year retrospective case-case-control study performed at the Detroit Medical Center on adult patients with bloodstream infection (BSI) caused by ESBL-producing and non-ESBL-producing Escherichia coli or Klebsiella pneumoniae, each compared with uninfected controls. Data were collected from December 2004-August 2009. Multivariate analysis was performed using logistic regression. Participants included 103 patients with BSI caused by ESBL-producing pathogens and 79 patients with BSI caused by pathogens that did not produce ESBLs. The mean age of patients in the ESBL group was 67 years; of the patients, 51% were men, 77% were black, and 38% (n = 39) died in hospital. The mean age of patients in the non-ESBL group was 58 years; of the patients, 51% were men, 92% were black, and 22% (n = 17) died in hospital. On multivariate analysis, predictors of BSI caused by ESBL-producing pathogens included central venous catheter (odds ratio [OR], 29.4; 95% confidence interval [CI], 3.0-288.3), prior β-lactam-/β-lactamase-inhibitor therapy (OR, 28.1; 95% CI, 1.99-396.5), and prior cefepime therapy (OR, 22.7; 95% CI, 2.7-192.4). The only risk factor for BSI caused by non-ESBL-producing pathogens was urinary catheter insertion (OR, 18.2; 95% CI, 3.3-100.3). Prior antimicrobial therapy, particularly with β-lactam, was the strongest unique risk factor for BSI caused by ESBL-producing E coli or K pneumoniae. Copyright © 2015. Published by Elsevier Inc.

  1. Optimization for Dwarf Banana with Microwave Low Temperature Carbon Dioxide Flash Puffing Process by Response Surface Methodology and Factor Analysis

    Directory of Open Access Journals (Sweden)

    Li Bao-Yu

    2016-01-01

    Full Text Available A three factors quadratic regression rotation combination design was adopted to optimize the technical conditions of microwave low temperature carbon dioxide flash puffing (MLTCDFP process for dwarf banana in the single factor’s foundation. This paper analyzed the effect of puffing temperature, puffing pressure, vacuum drying temperature and the interaction of the three factors on color, crispness, and the effect of hardness and water content. Based on the experimental data, the quadratic regression model of four indexes was deduced, then variables were analyzed with response surface methodology (RSM. The weights of four evaluation indexes was determined by factor analysis. The regression square was obtained by the comprehensive score as follow: Y=0.955+0.109X1+0.16X3−0.09X12+0.015X22 −0.15X32−0.018X1X2−0.056X1X3+0.016X2X3(R2=0.837.Through factor analysis, the range of the optimal technical conditions of MLTCDFP for dwarf banana obtained. The result indicated the four indexes were affected significantly by the puffing temperature and vacuum drying temperature, and the interactions of the three factors did not affect the product obviously. The optimal technical parameters were as follows: puffing temperature 91~95°C, puffing pressure 0.11~0.19MPa, vacuum temperature 81~85°C.

  2. Environmental and Physiological Factors Associated With Stamina in Dogs Exercising in High Ambient Temperatures

    Directory of Open Access Journals (Sweden)

    Patrick J. Robbins

    2017-09-01

    Full Text Available This IACUC approved study was performed to evaluate the environmental, physiological, and hematological components that contribute to stamina following successive bouts of exercise that included searching (5-min, agility (5-min, and ball retrieve (<10-min. Regularly exercised dogs (N = 12 were evaluated on five separate occasions. The population consisted of eight males and four females ranging in age from 8 to 23 months, which included six Labrador retrievers, three German shepherds, and one each English springer spaniel, German wirehaired pointer, and Dutch shepherd. The exercise period was up to 30 min with 5 min of intermittent rest between the exercise bouts or until a designated trainer determined that the dog appeared fatigued (e.g., curled tongue while panting, seeking shade, or voluntary reluctance to retrieve. At the end of the exercise period, pulse rate (PR, core temperature, blood lactate, and venous blood gas were collected. The median outdoor temperature was 28.9°C (84°F (IQR; 27.2–30°C/81–86°F and median humidity was 47% (IQR; 40–57%. Median duration of exercise was 27 min (IQR; 25–29. No dog showed signs of heat stress that required medical intervention. The components used to measure stamina in this study were total activity, post-exercise core body temperature (CBT, and increase in CBT. When controlling for breed, total activity, as measured by omnidirectional accelerometer device, could be predicted from a linear combination of the independent variables: pre-exercise activity (p = 0.008, post-exercise activity (p < 0.001, outdoor temperature (p = 0.005, reduction in base excess in extracellular fluid compartment (BEecf (p = 0.044, and decrease in TCO2 (p = 0.005. When controlling for breed and sex, increase in CBT could be predicted from a linear combination of the independent variables: study day (p = 0.005, increase in PR (p < 0.001, increase in lactate (p = 0

  3. Surface temperature-controlling factors during transaction of Mexican monsoon in the Sonoran Desert, North-West Mexico

    Science.gov (United States)

    Tereshchenko, I.; Zolotokrilin, A.; Titkova, T.; Brito, L.; Monzon, C.

    2009-12-01

    Correlation between albedo and dry land surface temperature can serve as an indicator of processes, which control the temperature. The term dry land is used in reference to arid, semi-arid and dry subhumid regions, whose humidification coefficient ranges between 0.05 and 0.65 according to United Nations Convention to combat desertification in those countries experiencing serious drought and desertification, particularly in Africa. Geneva, 1994. The three main competing factors of underlying surface temperature control are an inherent feature of dry lands: first - radiation, second - evapotranspiration, third - aerodynamic control. This study is focused on seasonal cycle of parameters, which control surface temperature in the Sonora desert (North-West Mexico). The understanding of this process is important for monitoring of desertification. This is so because in a certain year, the time span of the period, during which the radiation factor is predominant, is an important factor in the desertification process. One indirect characteristic of prevalence of the radiation factor is Normalized Difference Vegetation Index (NDVI), which is an indicator of green phytomass. The main features of the ratio between albedo and surface temperature are discussed in terms of analysis of monthly means (albedo, temperature, NDVI) in the state of Sonora (29-32N, 111-115W), in particular, within the box 30-31N, 112-113W. The analysis of synchronous time series of albedo, surface temperature and NDVI has shown that the dominating temperature-controlling factors can switch within the year in the study area. The radiation factor is dominant in dry months (April - May) and the surface temperature is negatively correlated with albedo. This can cause generation of positive albedo-precipitation feedback, which in turn contributes to the desertification process.

  4. Factors affecting process temperature and biogas production in small-scale rural biogas digesters in winter in northern Vietnam

    DEFF Research Database (Denmark)

    Cuong, Pham Hung; Vu, C.C.; Sommer, Sven G.

    2014-01-01

    and 180 cm, biogas production and methane (CH4) concentration in biogas from August to February. In parallel the temperature of the air (100 cm above ground), in the slurry mixing tank and in the soil (10, 100, 140, and 180 cm depth) was measured by thermocouple. The influent amount was measured daily...... and the influent chemical composition was measured monthly during the whole experimental period. Seasonal variations in air temperature significantly affected the temperature in the soil, mixing tank and digester. Consequently, biogas production, which is temperature dependent, was influenced by the season....... The main factors determining the internal temperature in the digesters were insulation with Styrofoam, air temperature and temperature of slurry in the mixing tank. Biogas production is low due to the cold climate conditions in winter in Northern Vietnam, but the study proved that storing slurry...

  5. RNA thermometer controls temperature-dependent virulence factor expression in Vibrio cholerae.

    Science.gov (United States)

    Weber, Gregor G; Kortmann, Jens; Narberhaus, Franz; Klose, Karl E

    2014-09-30

    Vibrio cholerae is the bacterium that causes the diarrheal disease cholera. The bacteria experience a temperature shift as V. cholerae transition from contaminated water at lower temperatures into the 37 °C human intestine. Within the intestine, V. cholerae express cholera toxin (CT) and toxin-coregulated pilus (TCP), two main virulence factors required for disease. CT and TCP expression is controlled by the transcriptional activator protein ToxT. We identified an RNA thermometer motif in the 5' UTR of toxT, with a fourU anti-Shine-Dalgarno (SD) element that base pairs with the SD sequence to regulate ribosome access to the mRNA. RNA probing experiments demonstrated that the fourU element allowed access to the SD sequence at 37 °C but not at 20 °C. Moreover, mutations within the fourU element (U5C, U7C) that strengthened base-pairing between the anti-SD and SD sequences prevented access to the SD sequence even at 37 °C. Translation of ToxT-FLAG from the native toxT UTR was enhanced at 37 °C, compared with 25 °C in both Escherichia coli and V. cholerae. In contrast, the U5C, U7C UTR prevented translation of ToxT-FLAG even at 37 °C. V. cholerae mutants containing the U5C, U7C UTR variant were unable to colonize the infant mouse small intestine. Our results reveal a previously unknown regulatory mechanism consisting of an RNA thermometer that controls temperature-dependent translation of toxT, facilitating V. cholerae virulence at a relevant environmental condition found in the human intestine.

  6. Including the spatial variability of metal speciation in the effect factor in life cycle impact assessment: Limits of the equilibrium partitioning method.

    Science.gov (United States)

    Tromson, Clara; Bulle, Cécile; Deschênes, Louise

    2017-03-01

    In life cycle assessment (LCA), the potential terrestrial ecotoxicity effect of metals, calculated as the effect factor (EF), is usually extrapolated from aquatic ecotoxicological data using the equilibrium partitioning method (EqP) as it is more readily available than terrestrial data. However, when following the AMI recommendations (i.e. with at least enough species that represents three different phyla), there are not enough terrestrial data for which soil properties or metal speciation during ecotoxicological testing are specified to account for the influence of soil property variations on metal speciation when using this approach. Alternatively, the TBLM (Terrestrial Biotic Ligand Model) has been used to determine an EF that accounts for speciation, but is not available for metals; hence it cannot be consistently applied to metals in an LCA context. This paper proposes an approach to include metal speciation by regionalizing the EqP method for Cu, Ni and Zn with a geochemical speciation model (the Windermere Humic Aqueous Model 7.0), for 5213 soils selected from the Harmonized World Soil Database. Results obtained by this approach (EF(EqP)regionalized) are compared to the EFs calculated with the conventional EqP method, to the EFs based on available terrestrial data and to the EFs calculated with the TBLM (EF(TBLM)regionalized) when available. The spatial variability contribution of the EF to the overall spatial variability of the characterization factor (CF) has been analyzed. It was found that the EFs(EqP)regionalized show a significant spatial variability. The EFs calculated with the two non-regionalized methods (EqP and terrestrial data) fall within the range of the EFs(EqP)regionalized. The EFs(TBLM)regionalized cover a larger range of values than the EFs(EqP)regionalized but the two methods are not correlated. This paper highlights the importance of including speciation into the terrestrial EF and shows that using the regionalized EqP approach is not an

  7. PHARMACOECONOMIC ASPECTS OF TREATMENT WITH THE INHIBITORS OF TUMOR NECROSIS FACTOR OF THE CHRONIC UVEITIS REFRACTORY TO THE BASIC THERAPY (INCLUDING AN ASSOCIATED WITH JUVENILE IDIOPATHIC ARTHRITIS

    Directory of Open Access Journals (Sweden)

    A.V. Rudakova

    2011-01-01

    Full Text Available Therapy of chronic uveitis refractory to the basic treatment, in juvenile idiopathic arthritis (JIA is a very complex problem in pediatrics. Substantial progress in this area resulted after the implementation in practice of inhibitors of tumor necrosis factor (TNF, as the most effective in such clinical situation drugs adalimumab and infliximab are considered (although infliximab was not officially approved in JIA. Objective. To estimate the cost effectiveness of TNF inhibitors — adalimumab, and infliximab in chronic uveitis, refractory to the basic therapy (including associated with juvenile rheumatoid arthritis. Methods. A modeling on the basis of a comparative prospective cohort clinical study was carried out. The analysis was performed by the method «cost–effectiveness» from a position of health and social accounting perspective. Results. It was shown that the frequency and time of remission did not differ when treatment with infliximab (5 mg/kg at 0–2–6 weeks and further once in 6–8 weeks and adalimumab (24 mg/m2 once in 2 weeks. Adalimumab provides a long-term maintenance of remission (no recurrence in 60% of patients within 40 months of observation, whereas 1 year after the treatment with infliximab the frequency of exacerbations was returned to that observed before therapy. The proportion of patients without relapse in the treatment with infliximab for 40 months was 18.8%. Similar results were obtained in a subset of patients with chronic uveitis associated with JIA (with follow-up of 20 months of in a group of infliximab number patients without relapse was 11.1%, with adalimumab therapy — 63.6%. In the general population of patients with refractory chronic uveitis the factor «cost–effectiveness» calculated for a patient with the maintenance of remission for 3 years with adalimumab therapy was in 2,1–2,8 times less than in the treatment with infliximab. In chronic uveitis associated with JIA, the coefficient of

  8. Psychosocial and behavioral factors associated with risk of sexually transmitted diseases, including human immunodeficiency virus infection, among urban high school students.

    Science.gov (United States)

    Shafer, M A; Boyer, C B

    1991-11-01

    The main purpose of this study was to evaluate the role of multiple psychosocial and knowledge-related antecedent factors that may predict sexual and alcohol and drug use behaviors that are associated with the transmission of sexually transmitted diseases (STDs), including human immunodeficiency virus infection. Five hundred forty-four ninth-grade urban high school students were surveyed regarding knowledge, attitudes, and behaviors related to STDs and acquired immunodeficiency syndrome (AIDS). Results of multiple regression analyses indicate that higher levels of STD and AIDS knowledge were associated with lower levels of STD and AIDS anxiety (R2 delta = 0.09; p less than 0.001), fewer negative attitudes toward people with AIDS (R2 delta = 0.09; p less than 0.001), stronger perceptions of self-efficacy (R2 delta = 0.03; p less than 0.01), and stronger peer affiliation (R2 delta = 0.02; p less than 0.05). Negative attitudes toward people with AIDS were inversely related to knowledge (R2 delta = 0.08; p less than 0.001), social support (R2 delta = 0.02; p less than 0.01), and perceived self-efficacy (R2 delta = 0.01; p less than 0.05). Predictors of alcohol and drug use included perceived peer norms (R2 delta = 0.08; p less than 0.001) and strong peer affiliation (R2 delta = 0.05; p less than 0.001). The best predictor of sexual risk behavior was alcohol and drug use (R2 delta = 0.07; p less than 0.001). Lower levels of knowledge (R2 delta = 0.14; p less than 0.01) and perceived peer norms (R2 delta = 0.05; p less than 0.05) predicted nonuse of condoms. Our results indicate that several factors relate to adolescent risk for STDs: the connection between peer influence and adolescent risk behaviors, the link between alcohol and drug use and sexual risk behavior, and the role of knowledge in determining nonuse of condoms.

  9. The cerium magnetic form factor and diffuse polarization in CeRh{sub 3}B{sub 2} as functions of temperature

    Energy Technology Data Exchange (ETDEWEB)

    Givord, F [CEA-Grenoble, DSM/DRFMC/SPSMS/MDN, 38054 Grenoble Cedex 9 (France); Boucherle, J-X [CEA-Grenoble, DSM/DRFMC/SPSMS/MDN, 38054 Grenoble Cedex 9 (France); Lelievre-Berna, E [Institut Laue-Langevin, BP156, 38042 Grenoble Cedex 9 (France); Lejay, P [CRTBT, CNRS, 166X, 38042 Grenoble Cedex 9 (France)

    2004-03-03

    In the compound CeRh{sub 3}B{sub 2}, a rather special polarization of the conduction electrons along the c-chains of cerium atoms had been previously reported at low temperatures (Alonso et al 1998 J. Magn. Magn. Mater. 177-181 1048). The distribution of the CeRh{sub 3}B{sub 2} magnetization has now been studied as a function of temperature up to 150 K-that is, above the Curie temperature of 115 K. The magnetization density maps have been obtained from polarized neutron diffraction experiments by using the maximum entropy method. The cerium form factor has also been analysed. Calculations of the form factor including several multiplets are developed and it is shown that it is necessary to take into account the influence of the higher multiplet of the Ce{sup 3+} ion. This result is coherent with the observation of a peak at high energy in the inelastic neutron spectra, indicating a very large crystal electric field splitting. Both analyses lead to the same conclusion that, on heating, the diffuse negative magnetization observed at low temperature along the cerium chains disappears at the magnetic ordering temperature. The influence of the second multiplet of the Ce{sup 3+} ion could be part of the explanation for the low value of the 4f moment and the large Curie temperature in CeRh{sub 3}B{sub 2}.

  10. Synergistic in vitro antioxidant activity and observational clinical trial of F105, a phytochemical formulation including Citrus bergamia, in subjects with moderate cardiometabolic risk factors.

    Science.gov (United States)

    Babish, John G; Dahlberg, Clinton J; Ou, Joseph J; Keller, William J; Gao, Wei; Kaadige, Mohan R; Brabazon, Holly; Lamb, Joseph; Soudah, Hani C; Kou, Xiaolan; Zhang, Zhe; Pacioretty, Linda M; Tripp, Matthew L

    2016-12-01

    We examined the clinical safety and efficacy of F105 in 11 subjects with moderate dyslipidemia. F105 is a combination of bergamot fruit extract (Citrus bergamia, BFE) and 9 phytoextracts selected for their ability to improve the antioxidant and anti-inflammatory activity of BFE. In vitro F105 exhibited a synergistic inhibition of oxygen radical absorbing capacity, peroxynitrite formation, and myeloperoxidase activity. Following 12 weeks of F105 daily, no treatment-related adverse events or changes in body mass were seen. Statistically significant changes were noted in total cholesterol (-7.3%), LDL-cholesterol (-10%), non-HDL cholesterol (-7.1%), cholesterol/HDL (-26%), and apolipoprotein B (-2.8%). A post hoc analysis of 8 subjects with HbA1c > 5.4 and HOMA-IR score > 2 or elevated triglycerides revealed additional statistically significant changes in addition to those previously observed in all subjects including triglycerides (-27%), oxLDL (-19%), LDL/HDL (-25%), triglycerides/HDL (-27%), oxLDL/HDL (-25%), and PAI-1 (-37%). A follow-up case report of a 70-year-old female patient, nonresponsive to statin therapy and placed on F105 daily, demonstrated improved cardiometabolic variables over 12 weeks similar to the subgroup. In summary, F105 was clinically well-tolerated and effective for ameliorating dyslipidemia in subjects with moderate cardiometabolic risk factors, particularly in the individuals with HbA1c > 5.4%.

  11. Dust temperature and CO-to-H2 conversion factor variations in the SFR-M* plane

    CERN Document Server

    Magnelli, B; Lutz, D; Tacconi, L J; Berta, S; Bournaud, F; Charmandaris, V; Dannerbauer, H; Elbaz, D; Förster-Schreiber, N M; Graciá-Carpio, J; Ivison, R; Maiolino, R; Nordon, R; Popesso, P; Rodighiero, G; Santini, P; Wuyts, S

    2012-01-01

    Deep Herschel imaging and 12CO(2-1) line luminosities from the IRAM PdBI are combined for a sample of 17 galaxies at z>1 from the GOODS-N field. The sample includes galaxies both on and above the main sequence (MS) traced by star-forming galaxies in the SFR-M* plane. The far-infrared data are used to derive dust masses, Mdust. Combined with an empirical prescription for the dependence of the gas-to-dust ratio on metallicity (GDR), the CO luminosities and Mdust values are used to derive for each galaxy the CO-to-H2 conversion factor, alpha_co. Like in the local Universe, the value of alpha_co is a factor of ~5 smaller in starbursts compared to normal star-forming galaxies (SFGs). We also uncover a relation between alpha_co and dust temperature (Tdust; alpha_co decreasing with increasing Tdust) as obtained from modified blackbody fits to the far-infrared data. While the absolute normalization of the alpha_co(Tdust) relation is uncertain, the global trend is robust against possible systematic biases in the deter...

  12. Optimal wavelengths obtained from laws analogous to the Wien's law for monospectral and bispectral methods, and general methodology for multispectral temperature measurements taking into account global transfer function including non-uniform emissivity of surfaces

    Science.gov (United States)

    Rodiet, Christophe; Remy, Benjamin; Degiovanni, Alain

    2016-05-01

    In this paper, it is shown how to select the optimal wavelengths minimizing the relative error and the standard deviation of the temperature. Furthermore, it is shown that the optimal wavelengths in mono-spectral and bi-spectral methods (for a Planck's law) can be determined by laws analogous to the displacement Wien's law. The simplicity of these laws can thus allow real-time selection of optimal wavelengths for a control/optimization of industrial processes, for example. A more general methodology to obtain the optimal wavelengths selection in a multi-spectral method (taking into account the spectral variations of the global transfer function including the emissivity variations) for temperature measurement of surfaces exhibiting non-uniform emissivity, is also presented. This latter can then find an interest in glass furnaces temperature measurement with spatiotemporal non-uniformities of emissivity, the control of biomass pyrolysis, the surface temperature measurement of buildings or heating devices, for example. The goal consists of minimizing the standard deviation of the estimated temperature (optimal design experiment). For the multi-spectral method, two cases will be treated: optimal global and optimal constrained wavelengths selection (to the spectral range of the detector, for example). The estimated temperature results obtained by different models and for different number of parameters and wavelengths are compared. These different points are treated from theoretical, numerical and experimental points of view.

  13. Retrospective multicenter matched case-control study on the risk factors for narcolepsy with special focus on vaccinations (including pandemic influenza vaccination) and infections in Germany.

    Science.gov (United States)

    Oberle, Doris; Pavel, Jutta; Mayer, Geert; Geisler, Peter; Keller-Stanislawski, Brigitte

    2017-06-01

    Studies associate pandemic influenza vaccination with narcolepsy. In Germany, a retrospective, multicenter, matched case-control study was performed to identify risk factors for narcolepsy, particularly regarding vaccinations (seasonal and pandemic influenza vaccination) and infections (seasonal and pandemic influenza) and to quantify the detected risks. Patients with excessive daytime sleepiness who had been referred to a sleep center between April 2009 and December 2012 for multiple sleep latency test (MSLT) were eligible. Case report forms were validated according to the criteria for narcolepsy defined by the Brighton Collaboration (BC). Confirmed cases of narcolepsy (BC level of diagnostic certainty 1-4a) were matched with population-based controls by year of birth, gender, and place of residence. A second control group was established including patients in whom narcolepsy was definitely excluded (test-negative controls). A total of 103 validated cases of narcolepsy were matched with 264 population-based controls. The second control group included 29 test-negative controls. A significantly increased odd ratio (OR) to develop narcolepsy (crude OR [cOR] = 3.9, 95% confidence interval [CI] = 1.8-8.5; adjusted OR [aOR] = 4.5, 95% CI = 2.0-9.9) was detected in individuals immunized with pandemic influenza A/H1N1/v vaccine prior to symptoms onset as compared to nonvaccinated individuals. Using test-negative controls, in individuals immunized with pandemic influenza A/H1N1/v vaccine prior to symptoms onset, a nonsignificantly increased OR of narcolepsy was detected when compared to nonvaccinated individuals (whole study population, BC levels 1-4a: cOR = 1.9, 95% CI = 0.5-6.9; aOR = 1.8, 95% CI = 0.3-10.1). The findings of this study support an increased risk for narcolepsy after immunization with pandemic influenza A/H1N1/v vaccine. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Multiple factors, including non-motor impairments, influence decision making with regard to exercise participation in Parkinson's disease: a qualitative enquiry.

    Science.gov (United States)

    O'Brien, Christine; Clemson, Lindy; Canning, Colleen G

    2016-01-01

    To explore how the meaning of exercise and other factors interact and influence the exercise behaviour of individuals with Parkinson's disease (PD) enrolled in a 6-month minimally supervised exercise program to prevent falls, regardless of whether they completed the prescribed exercise or not. This qualitative study utilised in-depth semi-structured interviews analysed using grounded theory methodology. Four main themes were constructed from the data: adapting to change and loss, the influence of others, making sense of the exercise experience and hope for a more active future. Participation in the PD-specific physiotherapy program involving group exercise provided an opportunity for participants to reframe their identity of their "active" self. Three new influences on exercise participation were identified and explored: non-motor impairments of apathy and fatigue, the belief in a finite energy quota, and the importance of feedback. A model was developed incorporating the themes and influences to explain decision-making for exercise participation in this group. Complex and interacting issues, including non-motor impairments, need to be considered in order to enhance the development and ongoing implementation of effective exercise programmes for people with PD. Exercise participation can assist individuals to reframe their identity as they are faced with losses associated with Parkinson's disease and ageing. Non-motor impairments of apathy and fatigue may influence exercise participation in people with Parkinson's disease. Particular attention needs to be paid to the provision of feedback in exercise programs for people with Parkinson's disease as it important for their decision-making about continuing exercise.

  15. Retrospective analysis of factors associated with outcome of proximal interphalangeal joint arthrodesis in 82 horses including Warmblood and Thoroughbred sport horses and Quarter Horses (1992-2014).

    Science.gov (United States)

    Herthel, T D; Rick, M C; Judy, C E; Cohen, N D; Herthel, D J

    2016-09-01

    Outcomes associated with arthrodesis of the proximal interphalangeal (PIP) joint in Quarter Horses used for Western performance activities are well documented but little is known regarding outcomes for other types of horses. To identify factors associated with outcomes, including breed and activity, after arthrodesis of the PIP joint in Warmbloods, Thoroughbreds and Quarter Horses. Retrospective case series. Surgical case records of 82 Quarter Horses principally engaged in Western performance and Thoroughbred or Warmblood breeds principally engaged in showing, showjumping and dressage, with arthrodesis of the PIP joint were reviewed. Arthrodesis was performed with either 3 transarticular cortex bone screws placed in lag fashion, a dynamic compression plate (DCP) with 2 transarticular cortex bone screws placed in lag fashion, or a locking compression plate (LCP) with 2 transarticular cortex bone screws placed in lag fashion. Demographic data, clinical presentation, radiographic findings, surgical technique, post operative treatment and complications were recorded. Long-term follow-up was obtained for all 82 horses. Osteoarthritis of the PIP joint was the most common presenting condition requiring arthrodesis, which was performed with either the 3 screw technique (n = 41), DCP fixation (n = 22), or LCP fixation (n = 19). Post operatively, 23/31 (74%) Warmbloods/Thoroughbreds and 44/51 (87%) Quarter Horses achieved successful outcomes. Thirteen of 23 (57%) Warmbloods/Thoroughbreds and 24 of 38 (63%) Quarter Horses, used for athletic performance, returned to successful competition. Within this subgroup of horses engaged in high-level activity, regardless of breed type, horses undergoing hindlimb arthrodesis were significantly more likely to return to successful competition (73%; 33/45) than those with forelimb arthrodesis (25%; 4/16, P = 0.002). Arthrodesis of the PIP joint in Warmbloods/Thoroughbreds and Quarter Horses results in a favourable outcome for return to

  16. Laser Microdissection Unravels Cell-Type-Specific Transcription in Arbuscular Mycorrhizal Roots, Including CAAT-Box Transcription Factor Gene Expression Correlating with Fungal Contact and Spread1[W

    Science.gov (United States)

    Hogekamp, Claudia; Arndt, Damaris; Pereira, Patrícia A.; Becker, Jörg D.; Hohnjec, Natalija; Küster, Helge

    2011-01-01

    Arbuscular mycorrhizae (AM) are the most widespread symbioses on Earth, promoting nutrient supply of most terrestrial plant species. To unravel gene expression in defined stages of Medicago truncatula root colonization by AM fungi, we here combined genome-wide transcriptome profiling based on whole mycorrhizal roots with real-time reverse transcription-PCR experiments that relied on characteristic cell types obtained via laser microdissection. Our genome-wide approach delivered a core set of 512 genes significantly activated by the two mycorrhizal fungi Glomus intraradices and Glomus mossae. Focusing on 62 of these genes being related to membrane transport, signaling, and transcriptional regulation, we distinguished whether they are activated in arbuscule-containing or the neighboring cortical cells harboring fungal hyphae. In addition, cortical cells from nonmycorrhizal roots served as a reference for gene expression under noncolonized conditions. Our analysis identified 25 novel arbuscule-specific genes and 37 genes expressed both in the arbuscule-containing and the adjacent cortical cells colonized by fungal hyphae. Among the AM-induced genes specifying transcriptional regulators were two members encoding CAAT-box binding transcription factors (CBFs), designated MtCbf1 and MtCbf2. Promoter analyses demonstrated that both genes were already activated by the first physical contact between the symbionts. Subsequently, and corresponding to our cell-type expression patterns, they were progressively up-regulated in those cortical areas colonized by fungal hyphae, including the arbuscule-containing cells. The encoded CBFs thus represent excellent candidates for regulators that mediate a sequential reprogramming of root tissues during the establishment of an AM symbiosis. PMID:22034628

  17. Influence of sky view factor on outdoor thermal environment and physiological equivalent temperature

    Science.gov (United States)

    He, Xiaodong; Miao, Shiguang; Shen, Shuanghe; Li, Ju; Zhang, Benzhi; Zhang, Ziyue; Chen, Xiujie

    2015-03-01

    Sky view factor (SVF), which is an indicator of urban canyon geometry, affects the surface energy balance, local air circulation, and outdoor thermal comfort. This study focused on a continuous and long-term meteorological observation system to investigate the effects of SVF on outdoor thermal conditions and physiological equivalent temperature (PET) in the central business district (CBD) of Beijing (which is located within Chaoyang District), specifically addressed current knowledge gaps for SVF-PET relationships in cities with typical continental/microthermal climates. An urban sub-domain scale model and the RayMan model were used to diagnose wind fields and to calculate SVF and long-term PET, respectively. Analytical results show that the extent of shading contributes to variations in thermal perception distribution. Highly shaded areas (SVF 0.5), and vice versa. Because Beijing has a monsoon-influenced humid continental climate with hot summers and long, cold, windy, and dry winters, a design project that ideally provides moderate shading should be planned to balance hot discomfort in summer and cold discomfort in winter, which effectively prolongs the comfort periods in outdoor spaces throughout the entire year. This research indicate that climate zone characteristics, urban environmental conditions, and thermal comfort requirements of residents must be accounted for in local-scale scientific planning and design, i.e., for urban canyon streets and residential estates.

  18. On the discharge capability and its limiting factors of commercial 18650 Li-ion cell at low temperatures

    Science.gov (United States)

    Fan, Jiang

    We here study the discharge capability of commercial 18650 cylindrical lithium-ion cells at low temperatures. The discharge capacity at -20 °C ranges from 67 to 88% of the rated capacity at 0.2 C rate, which is good. However, the cell discharge capacity varies substantially at -30 and -40 °C among the studied cells. It ranges from 2 to 70% of the rated capacity at -30 °C, and 0 to 30% at -40 °C at 0.2 C rate. The cell impedance at 1 kHz increases very little from room temperature down to -20 or -30 °C in general, which does not correlate with the cell discharge capability. However, the dc impedance is increased by a factor of about ten at -30 °C and about twenty at -40 °C from room temperature. The discharge capability at low temperature correlates well with the dc resistance at both room and low temperatures. The limiting factors in the discharge capability at low temperatures and the direction for the future improvement are discussed according to the cell discharge capability, the electrode geometric area, the cell impedance at 1 kHz, and the dc impedance at various temperatures. It appears that the ionic conductivity of the electrolyte and lithium solid diffusion in the electrode do not limit the cell discharge capability, while the lithium diffusion in the SEI layer on the positive surface may be the limiting factor. Cell discharge capability at low temperature does not correlate with cycle life at room temperature.

  19. Factors Affecting Transformation Temperatures in Fe-Mn-Si-Cr-Ni Shape Memory Alloy

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    @@The effects of prestrain and annealing temperature on phase transformation temperatures in Fe14Mn5Si8Cr4Ni shape memory alloy have been studied. The results showed that when the annealing temperature was 673 K, both the Af and the Ms temperatures increased appreciably as the prestrain increased, the As temperature increased slightly with increasing prestrain; the resistivity difference at 303 K between the heating and cooling curve also increased with increasing prestrain, which agreed with the recovery strain. The shape memory effect in Fe-Mn-Si-Cr-Ni shape memory alloy is caused by the stress-induced γ → ε martensite transformation and its reverse transformation. When the prestrain was 10%, the Ms temperature decreased remarkably as the annealing temperature increased.

  20. Temperature change and its effect factors in the Yangtze Delta, China

    Science.gov (United States)

    Shi, Jun; Tang, Xu; Cui, Linli; Gao, Zhiqiang

    2007-09-01

    Based on the meteorological data, land use date from TM images and social statistical data, the evidences of regional temperature change with the elements of mean annual temperature, mean annual maximum and minimum temperature, and extreme high and low temperature from 1959 to 2005, were detected, and the impact of human activities on temperature was analyzed in the Yangtze Delta region. The results indicated an increase in mean annual temperature, mean annual maximum and minimum temperature. Mean annual temperature in all cities in the region increased, and the increase rate in winter was greater than that in spring and autumn. The increase of mean annual maximum and minimum temperature was similar to that of mean annual temperature spatially. In 3 stations of Shanghai, Nanjing and Hangzhou, most hot days, least cold days and the highest mean temperature all appeared in the first 5 years in this century. Land use changed greatly, and a large amount of cropland was replaced with residential and constructional areas (R/C areas) from 1980 to 2000 in the Yangtze Delta region. The change of mean annual temperature was partly corresponding to the change of land use. Total registered population increased rapidly in 16 cities of the Yangtze Delta region, and a good linear correlation between the tendency ratio of total registered population and the mean annual temperature in 16 cities from 1978 to 2005. Total amount of energy consumption and GDP increased in 3 provinces of Shanghai, Jiangsu and Zhejiang where the Yangtze Delta located, both the final consumption of energy by industry and GDP had a relatively good linear relationship with the mean annual temperature in Shanghai from 1952 to 2005. This paper will help the understanding and attribution of climate change and simulation of the future response of weather-related disasters under various global change scenarios.

  1. [Analysis of the impact of the socio-economic factors on temperature-mortality association in southern China].

    Science.gov (United States)

    Hu, Mengjue; Ma, Wenjun; Zhang, Yonghui; Xu, Yanjun; Xu, Xiaojun; Lin, Hualiang; Liu, Tao; Xiao, Jianpeng; Luo, Yuan; Zeng, Weilin

    2014-05-01

    To explore the impact of the socio-economic factors on the temperature-mortality association in different cities in southern China. Daily mortality registration data, meteorological data and air pollution data of the cities as Changsha and Kunming during 2006-2009, and cities as Guangzhou and Zhuhai during 2006-2010, were collected to explore modifying effects, stratified by age, gender, education and place of death, of socio-economic factors on the association between temperature and mortality, by distributed lag non-linear model. The accumulative effect of temperature-mortality were separately analyzed in each city, under the high temperature (0-3 days) and low temperature (0-20 days) situation. The association between temperature and mortality was evaluated by general linear threshold model. The above process was firstly adopted to analyze the impact in single city and then Meta analysis was applied to analyze the impact in several cities by effect-combine. The relationship between temperature and mortality in the four cities showed nonlinearity. The minimum mortality risk was separately 23.5 °C, 20.5 °C, 25.0 °C and 26.0 °C in Changsha, Kunming, Guangzhou and Zhuhai. The results of effect-combine showed that low-temperature (RR = 1.67, 95%CI:1.54-1.80) has a higher gross effect than high-temperature (RR = 1.11, 95%CI:1.01-1.18) on population. With the age increasing, risk of death increased both under high and low temperature situation, and the effect of low temperature was greater (RR = 1.83, 95%CI:1.65-2.04) for the elderly than it of high temperature (RR = 1.17, 95%CI:1.03-1.33). The mortality risk among females (cold and hot effects(95%CI) were 1.75(1.57-1.97) and 1.11(0.99-1.25), respectively)was higher than it among males (cold and hot effects(95%CI) were 1.59(1.45-1.77) and 1.11(1.03-1.19), respectively). Whereas the mortality risk on higher education population was significantly higher (cold and hot effects (95%CI) were 1.89(1.48-2.45)and 1

  2. Temperature-dependent magnetostriction as the key factor for martensite reorientation in magnetic field

    Science.gov (United States)

    L'vov, Victor A.; Kosogor, Anna

    2016-09-01

    The magnetic field application leads to spatially inhomogeneous magnetostriction of twinned ferromagnetic martensite. When the increasing field and magnetostrictive strain reach certain threshold values, the motion of twin boundaries and magnetically induced reorientation (MIR) of twinned martensite start. The MIR leads to giant magnetically induced deformation of twinned martensite. In the present article, the threshold field (TF) and temperature range of observability of MIR were calculated for the Ni-Mn-Ga martensite assuming that the threshold strain (TS) is temperature-independent. The calculations show that if the TS is of the order of 10-4, the TF strongly depends on temperature and MIR can be observed only above the limiting temperature (~220 K). If the TS is of the order of 10-6, the TF weakly depends on temperature and MIR can be observed at extremely low temperatures. The obtained theoretical results are in agreement with available experimental data.

  3. Induction of dormancy in Arabidopsis summer annuals requires parallel regulation of DOG1 and hormone metabolism by low temperature and CBF transcription factors.

    Science.gov (United States)

    Kendall, Sarah L; Hellwege, Anja; Marriot, Poppy; Whalley, Celina; Graham, Ian A; Penfield, Steven

    2011-07-01

    Summer annuals overwinter as seeds in the soil seed bank. This is facilitated by a cold-induced increase in dormancy during seed maturation followed by a switch to a state during seed imbibition in which cold instead promotes germination. Here, we show that the seed maturation transcriptome in Arabidopsis thaliana is highly temperature sensitive and reveal that low temperature during seed maturation induces several genes associated with dormancy, including DELAY OF GERMINATION1 (DOG1), and influences gibberellin and abscisic acid levels in mature seeds. Mutants lacking DOG1, or with altered gibberellin or abscisic acid synthesis or signaling, in turn show reduced ability to enter the deeply dormant states in response to low seed maturation temperatures. In addition, we find that DOG1 promotes gibberellin catabolism during maturation. We show that C-REPEAT BINDING FACTORS (CBFs) are necessary for regulation of dormancy and of GA2OX6 and DOG1 expression caused by low temperatures. However, the temperature sensitivity of CBF transcription is markedly reduced in seeds and is absent in imbibed seeds. Our data demonstrate that inhibition of CBF expression is likely a critical feature allowing cold to promote rather than inhibit germination and support a model in which CBFs act in parallel to a low-temperature signaling pathway in the regulation of dormancy.

  4. Induction of Dormancy in Arabidopsis Summer Annuals Requires Parallel Regulation of DOG1 and Hormone Metabolism by Low Temperature and CBF Transcription Factors[W][OA

    Science.gov (United States)

    Kendall, Sarah L.; Hellwege, Anja; Marriot, Poppy; Whalley, Celina; Graham, Ian A.; Penfield, Steven

    2011-01-01

    Summer annuals overwinter as seeds in the soil seed bank. This is facilitated by a cold-induced increase in dormancy during seed maturation followed by a switch to a state during seed imbibition in which cold instead promotes germination. Here, we show that the seed maturation transcriptome in Arabidopsis thaliana is highly temperature sensitive and reveal that low temperature during seed maturation induces several genes associated with dormancy, including DELAY OF GERMINATION1 (DOG1), and influences gibberellin and abscisic acid levels in mature seeds. Mutants lacking DOG1, or with altered gibberellin or abscisic acid synthesis or signaling, in turn show reduced ability to enter the deeply dormant states in response to low seed maturation temperatures. In addition, we find that DOG1 promotes gibberellin catabolism during maturation. We show that C-REPEAT BINDING FACTORS (CBFs) are necessary for regulation of dormancy and of GA2OX6 and DOG1 expression caused by low temperatures. However, the temperature sensitivity of CBF transcription is markedly reduced in seeds and is absent in imbibed seeds. Our data demonstrate that inhibition of CBF expression is likely a critical feature allowing cold to promote rather than inhibit germination and support a model in which CBFs act in parallel to a low-temperature signaling pathway in the regulation of dormancy. PMID:21803937

  5. Daily changes of radon concentration in soil gas under influence of atmospheric factors: room temperature, soil surface temperature and relative humidity

    Energy Technology Data Exchange (ETDEWEB)

    Lara, Evelise G.; Oliveira, Arno Heeren de, E-mail: evelise.lara@gmail.com, E-mail: heeren@nuclear.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear; Rocha, Zildete; Rios, Francisco Javier, E-mail: rochaz@cdtn.br, E-mail: javier@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2015-07-01

    This work aims at relating the daily change in the radon concentration in soil gas in a Red Yellow Acrisol (SiBCS) under influence of atmospheric factors: room temperature, soil surface temperature and relative humidity. The {sup 226}Ra, {sup 232}Th, U content and permeability were also performed. The measurements of radon soil gas were carried out by using an AlphaGUARD monitor. The {sup 226}Ra activity concentration was made by Gamma Spectrometry (HPGe); the permeability was carried out using the RADON-JOK permeameter and ICP-MS analysis to {sup 232}Th and U content. The soil permeability is 5.0 x 10{sup -12}, which is considered average. The {sup 226}Ra (22.2 ± 0.3 Bq.m{sup -3}); U content (73.4 ± 3.6 Bq.kg{sup -1}) and {sup 232}Th content (55.3 ± 4.0 Bq.kg{sup -1}) were considered above of average concentrations, according to mean values for soils typical (~ 35.0 Bq.kg{sup -1}) by UNSCEAR. The results showed a difference of 26.0% between the highest and the lowest concentration of radon in soil gas: at midnight (15.5 ± 1.0 kBq.m{sup -3}) and 3:00 pm, the highest mean radon concentration (21.0 ± 1.0 kBq.m{sup -3}). The room temperature and surface soil temperature showed equivalent behavior and the surface soil temperature slightly below room temperature during the entire monitoring time. Nevertheless, the relative humidity showed the highest cyclical behavior, showing a higher relationship with the radon concentration in soil gas. (author)

  6. Human factors issues and approaches in the spatial layout of a space station control room, including the use of virtual reality as a design analysis tool

    Science.gov (United States)

    Hale, Joseph P., II

    1994-01-01

    Human Factors Engineering support was provided for the 30% design review of the late Space Station Freedom Payload Control Area (PCA). The PCA was to be the payload operations control room, analogous to the Spacelab Payload Operations Control Center (POCC). This effort began with a systematic collection and refinement of the relevant requirements driving the spatial layout of the consoles and PCA. This information was used as input for specialized human factors analytical tools and techniques in the design and design analysis activities. Design concepts and configuration options were developed and reviewed using sketches, 2-D Computer-Aided Design (CAD) drawings, and immersive Virtual Reality (VR) mockups.

  7. Experimental factors that influence carbon monoxide tolerance of high-temperature proton-exchange membrane fuel cells

    Science.gov (United States)

    Kwon, Kyungjung; Yoo, Duck Young; Park, Jung Ock

    The poisoning effect of carbon monoxide (CO) on high-temperature proton-exchange membrane fuel cells (PEMFCs) is investigated with respect to CO concentration, operating temperature, fuel feed mode, and anode Pt loading. The loss in cell voltage when CO is added to pure hydrogen anode gas is a function of fuel utilization and anode Pt loading as well as obvious factors such as CO concentration, temperature and current density. The tolerance to CO can be varied significantly using a different experimental design of fuel utilization and anode Pt loading. A difference in cell performance with CO-containing hydrogen is observed when two cells with different flow channel geometries are used, although the two cells show similar cell performance with pure hydrogen. A different combination of fuel utilization, anode Pt loading and flow channel design can cause an order of magnitude difference in CO tolerance under identical experimental conditions of temperature and current density.

  8. Experimental factors that influence carbon monoxide tolerance of high-temperature proton-exchange membrane fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Kyungjung; Yoo, Duck Young; Park, Jung Ock [Energy and Environment Lab, Samsung Advanced Institute of Technology, Nongseo-dong, Giheung-gu, Yongin-si, Gyeonggi-do 446-712 (Korea)

    2008-10-15

    The poisoning effect of carbon monoxide (CO) on high-temperature proton-exchange membrane fuel cells (PEMFCs) is investigated with respect to CO concentration, operating temperature, fuel feed mode, and anode Pt loading. The loss in cell voltage when CO is added to pure hydrogen anode gas is a function of fuel utilization and anode Pt loading as well as obvious factors such as CO concentration, temperature and current density. The tolerance to CO can be varied significantly using a different experimental design of fuel utilization and anode Pt loading. A difference in cell performance with CO-containing hydrogen is observed when two cells with different flow channel geometries are used, although the two cells show similar cell performance with pure hydrogen. A different combination of fuel utilization, anode Pt loading and flow channel design can cause an order of magnitude difference in CO tolerance under identical experimental conditions of temperature and current density. (author)

  9. Dominant factors affecting temperature rise in simulations of human thermoregulation during RF exposure

    Science.gov (United States)

    Laakso, Ilkka; Hirata, Akimasa

    2011-12-01

    Numerical models of the human thermoregulatory system can be used together with realistic voxel models of the human anatomy to simulate the body temperature increases caused by the power absorption from radio-frequency electromagnetic fields. In this paper, the Pennes bioheat equation with a thermoregulatory model is used for calculating local peak temperatures as well as the body-core-temperature elevation in a realistic human body model for grounded plane-wave exposures at frequencies 39, 800 and 2400 MHz. The electromagnetic power loss is solved by the finite-difference time-domain (FDTD) method, and the discretized bioheat equation is solved by the geometric multigrid method. Human thermoregulatory models contain numerous thermophysiological and computational parameters—some of which may be subject to considerable uncertainty—that affect the simulated core and local temperature elevations. The goal of this paper is to find how greatly the computed temperature is influenced by changes in various modelling parameters, such as the skin blood flow rate, models for vasodilation and sweating, and clothing and air movement. The results show that the peak temperature rises are most strongly affected by the modelling of tissue blood flow and its temperature dependence, and mostly unaffected by the central control mechanism for vasodilation and sweating. Almost the opposite is true for the body-core-temperature rise, which is however typically greatly lower than the peak temperature rise. It also seems that ignoring the thermoregulation and the blood temperature increase is a good approximation when the local 10 g averaged specific absorption rate is smaller than 10 W kg-1.

  10. Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis

    DEFF Research Database (Denmark)

    Bendtzen, K; Hansen, P R; Rieneck, K

    2003-01-01

    for up to 22 months with 1-3 mg/kg/day. Spironolactone, at in vivo attainable doses, markedly suppressed transcription of several proinflammatory cytokines and, accordingly, inhibited release of tumour necrosis factor, lymphotoxin, interferon-gamma, granulocyte-macrophage colony-stimulating factor....... In conclusion, spironolactone inhibits production of several proinflammatory cytokines considered to be of pathogenic importance in many immunoinflammatory diseases and shows positive effect in patients with chronic arthritis. Its effect as an anti-inflammatory drug should be explored, because prolonged...... and interleukin 6 (70-90% inhibition). Release of these cytokines was also suppressed when testing whole blood from RA patients receiving 50 mg spironolactone twice daily, indicating that pharmaceutical use of the drug may suppress the release of inflammatory cytokines. Spironolactone therapy was generally well...

  11. Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis

    DEFF Research Database (Denmark)

    Bendtzen, K; Hansen, P R; Rieneck, K

    2003-01-01

    ,000 genes) and enzyme immunoassay for quantitating secreted pro- and anti-inflammatory cytokines. Furthermore, to evaluate the safety and efficacy of spironolactone as an anti-inflammatory drug 21 patients with rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA) or other arthritides were treated...... for up to 22 months with 1-3 mg/kg/day. Spironolactone, at in vivo attainable doses, markedly suppressed transcription of several proinflammatory cytokines and, accordingly, inhibited release of tumour necrosis factor, lymphotoxin, interferon-gamma, granulocyte-macrophage colony-stimulating factor...... and interleukin 6 (70-90% inhibition). Release of these cytokines was also suppressed when testing whole blood from RA patients receiving 50 mg spironolactone twice daily, indicating that pharmaceutical use of the drug may suppress the release of inflammatory cytokines. Spironolactone therapy was generally well...

  12. How to maintain the sperm quality during the semen processing in assisted reproductive technology? The temperature factor

    Directory of Open Access Journals (Sweden)

    A. V. Zobova

    2015-02-01

    Full Text Available In connection with broad distribution of auxiliary reproductive technologies, it is important to secure optimal conditions for keeping thermal tolerance of sperm cells. There is direct correlation between the quality of sperm cells and sperm samples storage temperature, that is why support of adequate temperature is required to keep the fertilizing capacity of sperm in vitro. However, the temperature at which sperm cells keep their functional characteristics after ejaculation in the best way is still the subject of many discussions, and information on the temperature conditions that are the best to incubate sperm is rather contradictory. Vast majority of publications report the damaging effect of excessive heating on the sperm quality. However, incubation of samples of treated sperm in such temperature conditions is still practiced in many embryology laboratories. A literate approach to the selection of conditions of treatment and storage of sperm prior to its usage for c which takes into account the temperature factor will improve functional characteristics of sperm cells such as their agility, morphology, and fertilizing capacity. The review presented provides analysis of modern data of dependency of the quality of sperm on the incubation temperature prior to performance of the artificial insemination procedure.

  13. Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti–factor VIII immune responses

    OpenAIRE

    Ettinger, Ruth A.; James, Eddie A.; Kwok, William W.; Arthur R Thompson; Pratt, Kathleen P.

    2009-01-01

    The development of neutralizing antibodies (inhibitors) after factor VIII (FVIII) infusions is a serious complication that affects approximately one-quarter of hemophilia A patients who have access to replacement therapy. To investigate the differentiation of naive T cells into FVIII-specific helper T cells that promote B-cell activation and antibody secretion, HLA-DRA-DRB1*0101-restricted T-cell clones that respond to a specific epitope in FVIII were isolated from a mild hemophilia A subject...

  14. Disease-related and psychosocial factors associated with depressive symptoms in patients with systemic sclerosis, including fear of progression and appearance self-esteem.

    Science.gov (United States)

    Kwakkenbos, Linda; van Lankveld, Wim G J M; Vonk, Madelon C; Becker, Eni S; van den Hoogen, Frank H J; van den Ende, Cornelia H M

    2012-03-01

    The prevalence of depressive symptoms is high in patients with systemic sclerosis (SSc, scleroderma). This study was conducted to determine which disease-related and psychosocial factors are associated with depressive symptoms, independent of sociodemographic factors. In total, 215 patients with SSc completed questionnaires on sociodemographics, physical functioning (HAQ-DI), pain (VAS), fatigue (CIS), psychosocial characteristics (CISS, ICQ, PRQ, ASE, FoP-Q-SF) and depressive symptoms (CES-D). Disease characteristics (disease duration, disease subtype, modified Rodnan Skin Score) were collected. Hierarchical linear regression analyses were conducted to assess associations with depressive symptoms. The mean CES-D score was 12.9 (SD=9.7) and the prevalence of patients scoring>= 16 and>=19 were 32.1% and 25.1%, respectively. The variance explained by sociodemographics and disease characteristics was negligible (R(2)≤.09). Fatigue and pain were independently associated with depressive symptoms (R(2) change=.35). After adding psychological factors (R(2) change=.21), satisfaction with social support, emotion-focused coping and helplessness were also significantly associated with depressive symptoms. Higher fear of progression was associated with more depressive symptoms (P≤.01), and appearance self-esteem showed a marginally significant association (P=.08). Depressive symptoms were common in the present sample of patients with SSc and were independently associated with pain, fatigue, social support, emotion-focused coping, helplessness and fear of progression. Results suggest that, in addition to assessment of disease characteristics, attention should be given also to psychosocial factors found to be associated with depressive symptoms. For the development and trialling of psychological interventions, fear of progression could be an important target. Copyright © 2011 Elsevier Inc. All rights reserved.

  15. Resource supply overrides temperature as a controlling factor of marine phytoplankton growth.

    Science.gov (United States)

    Marañón, Emilio; Cermeño, Pedro; Huete-Ortega, María; López-Sandoval, Daffne C; Mouriño-Carballido, Beatriz; Rodríguez-Ramos, Tamara

    2014-01-01

    The universal temperature dependence of metabolic rates has been used to predict how ocean biology will respond to ocean warming. Determining the temperature sensitivity of phytoplankton metabolism and growth is of special importance because this group of organisms is responsible for nearly half of global primary production, sustains most marine food webs, and contributes to regulate the exchange of CO2 between the ocean and the atmosphere. Phytoplankton growth rates increase with temperature under optimal growth conditions in the laboratory, but it is unclear whether the same degree of temperature dependence exists in nature, where resources are often limiting. Here we use concurrent measurements of phytoplankton biomass and carbon fixation rates in polar, temperate and tropical regions to determine the role of temperature and resource supply in controlling the large-scale variability of in situ metabolic rates. We identify a biogeographic pattern in phytoplankton metabolic rates, which increase from the oligotrophic subtropical gyres to temperate regions and then coastal waters. Variability in phytoplankton growth is driven by changes in resource supply and appears to be independent of seawater temperature. The lack of temperature sensitivity of realized phytoplankton growth is consistent with the limited applicability of Arrhenius enzymatic kinetics when substrate concentrations are low. Our results suggest that, due to widespread resource limitation in the ocean, the direct effect of sea surface warming upon phytoplankton growth and productivity may be smaller than anticipated.

  16. Resource supply overrides temperature as a controlling factor of marine phytoplankton growth.

    Directory of Open Access Journals (Sweden)

    Emilio Marañón

    Full Text Available The universal temperature dependence of metabolic rates has been used to predict how ocean biology will respond to ocean warming. Determining the temperature sensitivity of phytoplankton metabolism and growth is of special importance because this group of organisms is responsible for nearly half of global primary production, sustains most marine food webs, and contributes to regulate the exchange of CO2 between the ocean and the atmosphere. Phytoplankton growth rates increase with temperature under optimal growth conditions in the laboratory, but it is unclear whether the same degree of temperature dependence exists in nature, where resources are often limiting. Here we use concurrent measurements of phytoplankton biomass and carbon fixation rates in polar, temperate and tropical regions to determine the role of temperature and resource supply in controlling the large-scale variability of in situ metabolic rates. We identify a biogeographic pattern in phytoplankton metabolic rates, which increase from the oligotrophic subtropical gyres to temperate regions and then coastal waters. Variability in phytoplankton growth is driven by changes in resource supply and appears to be independent of seawater temperature. The lack of temperature sensitivity of realized phytoplankton growth is consistent with the limited applicability of Arrhenius enzymatic kinetics when substrate concentrations are low. Our results suggest that, due to widespread resource limitation in the ocean, the direct effect of sea surface warming upon phytoplankton growth and productivity may be smaller than anticipated.

  17. The impact of climatic and non-climatic factors on land surface temperature in southwestern Romania

    Science.gov (United States)

    Roşca, Cristina Florina; Harpa, Gabriela Victoria; Croitoru, Adina-Eliza; Herbel, Ioana; Imbroane, Alexandru Mircea; Burada, Doina Cristina

    2016-09-01

    Land surface temperature is one of the most important parameters related to global warming. It depends mainly on soil type, discontinuous vegetation cover, or lack of precipitation. The main purpose of this paper is to investigate the relationship between high LST, synoptic conditions and air masses trajectories, vegetation cover, and soil type in one of the driest region in Romania. In order to calculate the land surface temperature and normalized difference vegetation index, five satellite images of LANDSAT missions 5 and 7, covering a period of 26 years (1986-2011), were selected, all of them collected in the month of June. The areas with low vegetation density were derived from normalized difference vegetation index, while soil types have been extracted from Corine Land Cover database. HYSPLIT application was employed to identify the air masses origin based on their backward trajectories for each of the five study cases. Pearson, logarithmic, and quadratic correlations were used to detect the relationships between land surface temperature and observed ground temperatures, as well as between land surface temperature and normalized difference vegetation index. The most important findings are: strong correlation between land surface temperature derived from satellite images and maximum ground temperature recorded in a weather station located in the area, as well as between areas with land surface temperature equal to or higher than 40.0 °C and those with lack of vegetation; the sandy soils are the most prone to high land surface temperature and lack of vegetation, followed by the chernozems and brown soils; extremely severe drought events may occur in the region.

  18. Factors associated with early adoption of the HPV vaccine in US male adolescents include Hispanic ethnicity and receipt of other vaccines

    Directory of Open Access Journals (Sweden)

    Deanna Kepka

    2016-12-01

    Full Text Available Adolescent males' HPV vaccine initiation and completion in the United States is far below the Healthy People 2020 goal of 80% 3-dose completion among boys. In 2012, less than 7% of males ages 13–17 years had completed the 3-dose series. The Diffusion of Innovations framework guided this investigation of factors related to early adoption of HPV vaccination among male adolescents. Provider-validated data from the 2012 National Immunization Survey-Teen (NIS-Teen for male adolescents ages 13–17 years were analyzed via a multivariable Poisson regression to estimate prevalence ratios for factors associated with HPV vaccine initiation and completion. Adolescent males who are Hispanic and those who are up to date on other recommended adolescent vaccinations were most likely to complete the HPV vaccine. Public health interventions are needed to improve low HPV vaccination rates among adolescent males in the United States. Description of early adopters of the HPV vaccine provides historical context of HPV vaccination acceptance that is needed to inform the design of targeted vaccination interventions to prevent negative HPV-associated outcomes.

  19. Factors associated with early adoption of the HPV vaccine in US male adolescents include Hispanic ethnicity and receipt of other vaccines.

    Science.gov (United States)

    Kepka, Deanna; Ding, Qian; Hawkins, Amy J; Warner, Echo L; Boucher, Kenneth M

    2016-12-01

    Adolescent males' HPV vaccine initiation and completion in the United States is far below the Healthy People 2020 goal of 80% 3-dose completion among boys. In 2012, less than 7% of males ages 13-17 years had completed the 3-dose series. The Diffusion of Innovations framework guided this investigation of factors related to early adoption of HPV vaccination among male adolescents. Provider-validated data from the 2012 National Immunization Survey-Teen (NIS-Teen) for male adolescents ages 13-17 years were analyzed via a multivariable Poisson regression to estimate prevalence ratios for factors associated with HPV vaccine initiation and completion. Adolescent males who are Hispanic and those who are up to date on other recommended adolescent vaccinations were most likely to complete the HPV vaccine. Public health interventions are needed to improve low HPV vaccination rates among adolescent males in the United States. Description of early adopters of the HPV vaccine provides historical context of HPV vaccination acceptance that is needed to inform the design of targeted vaccination interventions to prevent negative HPV-associated outcomes.

  20. Psychophysics of a nociceptive test in the mouse: ambient temperature as a key factor for variation.

    Directory of Open Access Journals (Sweden)

    Ivanne Pincedé

    Full Text Available BACKGROUND: The mouse is increasingly used in biomedical research, notably in behavioral neurosciences for the development of tests or models of pain. Our goal was to provide the scientific community with an outstanding tool that allows the determination of psychophysical descriptors of a nociceptive reaction, which are inaccessible with conventional methods: namely the true threshold, true latency, conduction velocity of the peripheral fibers that trigger the response and latency of the central decision-making process. METHODOLOGY/PRINCIPAL FINDINGS: Basically, the procedures involved heating of the tail with a CO(2 laser, recording of tail temperature with an infrared camera and stopping the heating when the animal reacted. The method is based mainly on the measurement of three observable variables, namely the initial temperature, the heating rate and the temperature reached at the actual moment of the reaction following random variations in noxious radiant heat. The initial temperature of the tail, which itself depends on the ambient temperature, very markedly influenced the behavioral threshold, the behavioral latency and the conduction velocity of the peripheral fibers but not the latency of the central decision-making. CONCLUSIONS/SIGNIFICANCE: We have validated a psychophysical approach to nociceptive reactions for the mouse, which has already been described for rats and Humans. It enables the determination of four variables, which contribute to the overall latency of the response. The usefulness of such an approach was demonstrated by providing new fundamental findings regarding the influence of ambient temperature on nociceptive processes. We conclude by challenging the validity of using as "pain index" the reaction time of a behavioral response to an increasing heat stimulus and emphasize the need for a very careful control of the ambient temperature, as a prevailing environmental source of variation, during any behavioral testing of

  1. Uncovering different masking factors on wrist skin temperature rhythm in free-living subjects.

    Directory of Open Access Journals (Sweden)

    Antonio Martinez-Nicolas

    Full Text Available Most circadian rhythms are controlled by a major pacemaker located in the hypothalamic suprachiasmatic nucleus. Some of these rhythms, called marker rhythms, serve to characterize the timing of the internal temporal order. However, these variables are susceptible to masking effects as the result of activity, body position, light exposure, environmental temperature and sleep. Recently, wrist skin temperature (WT has been proposed as a new index for evaluating circadian system status. In light of previous evidence suggesting the important relationship between WT and core body temperature regulation, the aim of this work was to purify the WT pattern in order to obtain its endogenous rhythm with the application of multiple demasking procedures. To this end, 103 subjects (18-24 years old were recruited and their WT, activity, body position, light exposure, environmental temperature and sleep were recorded under free-living conditions for 1 week. WT demasking by categories or intercepts was applied to simulate a "constant routine" protocol (awakening, dim light, recumbent position, low activity and warm environmental temperature. Although the overall circadian pattern of WT was similar regardless of the masking effects, its amplitude was the rhythmic parameter most affected by environmental conditions. The acrophase and mesor were determined to be the most robust parameters for characterizing this rhythm. In addition, a circadian modulation of the masking effect was found for each masking variable. WT rhythm exhibits a strong endogenous component, despite the existence of multiple external influences. This was evidenced by simultaneously eliminating the influence of activity, body position, light exposure, environmental temperature and sleep. We therefore propose that it could be considered a valuable and minimally-invasive means of recording circadian physiology in ambulatory conditions.

  2. [Dynamics of seasonal plant growth in halophytic meadows taking into account the temperature factor and soil salinity level].

    Science.gov (United States)

    Pis'man, T I; Slosar', N A

    2012-01-01

    A mathematical model has been constructed to describe the growth dynamics of various plant communities of halophytic meadows depending on the temperature factor and degree of soil salinity. Field investigation of the yields of halophytic meadow plant communities were performed in the coastal area of Kurinka Lake in the Altaiskii district of the Republic of Khakasia in 2004 and 2006. The results of field investigations and model studies show that there is a correlation between plant growth and air temperature for plant communities growing on soils with the lowest and medium salinity levels. It was proven in model studies that for the plant communities that grow on highly saline (3.58%) soils, not only air temperature but also the salinity level of the soil should be taken into account.

  3. Development of multidrug resistance due to multiple factors including P-glycoprotein overexpression under K-selection after MYC and HRAS oncogene activation.

    Science.gov (United States)

    Nakamura, Yukari; Sato, Hiroyuki; Motokura, Toru

    2006-05-15

    Multistep tumorigenesis is a form of microevolution consisting of mutation and selection. To clarify the role of selection modalities in tumor development, we examined two alternative evolutionary conditions, r-selection in sparse culture, which allows cells to proliferate rapidly, and K-selection in confluent culture, in which overcrowding constrains cell proliferation. Using MYC- and EJ-RAS-transformed rat embryo fibroblasts, we found that K-selected cells acquired and stably maintained multidrug resistance (MDR) to DOX, VCR, MTX and Ara-C. Then, we examined the involvement of a number of factors potentially causal of the development of MDR, that is, ploidy, Tp53 mutation, doubling time and the expression levels of genes related to drug resistance. Although ploidy status and Tp53 mutations did not correlate with MDR, we found that Abcb1/Mdr1, encoding P-glycoprotein (Pgp), was significantly upregulated after K-selection. Cyclosporin A, a competitive inhibitor of Pgp, increased the intracellular accumulation of DOX and reduced the resistance to it. Indeed, the population of Pgp-transfected cells significantly expanded under K-, but not under r-selection. In addition to Pgp upregulation, altered expression of other genes such as Cda/cytidine deaminase and Slc29a1/equilibrative nucleoside transporter 1 and prolonged doubling times were associated with MDR. This system reproduces events associated with MDR in vivo and would be useful for analysis of MDR development.

  4. Real-world Experience with Sofosbuvir-based Regimens for Chronic Hepatitis C, Including Patients with Factors Previously Associated with Inferior Treatment Response.

    Science.gov (United States)

    Wu, Christina J; Roytman, Marina M; Hong, Leena K; Huddleston, Leslie; Trujillo, Ruby; Cheung, Alvin; Poerzgen, Peter; Tsai, Naoky C S

    2015-09-01

    The introduction of sofosbuvir, a direct acting antiviral, has revolutionized the treatment of chronic hepatitis C virus (HCV). Phase 3 clinical trials have demonstrated the efficacy, simplicity, and tolerability of sofosbuvir-based regimens and report high rates of sustained virological response (SVR) rates. The purpose of this study was to assess whether clinical trial findings translate into a real-world setting, particularly with treatment of chronic HCV in our diverse, multiethnic population of Hawai'i. Retrospective analysis was performed for 113 patients with genotype 1-6 HCV infection being treated at the Queen's Liver Center between January 2014 and March 2015. SVR rates for our cohort were slightly lower than the rates published by the clinical trials. Data analysis also suggested that most baseline characteristics previously associated with inferior response might not be as significant for sofosbuvir-based regimens; in our cohort, male gender was the only factor significantly related to increased risk of virologic relapse. Pacific Islanders also had higher rate of relapse compared to other ethnic groups, but the small number of patients treated in this subgroup make it difficult to validate this finding. While newer all-oral treatment regimens have been introduced since this study, we highlight the importance of comparing real-world versus clinical trial results for new treatments, and provide data analyses for treatment of chronic HCV in Hawai'i.

  5. Evaluating the prevalence of canceling surgical operations,including its influencing factors at Imam Khomeini hospital in Sari during 2006-2007

    Directory of Open Access Journals (Sweden)

    A. Zamani kiasari

    2008-01-01

    Full Text Available AbstractBackground and Purpose: Hospital admission for surgery is an important event for patients. Canceling surgical procedures produce several unpleasant results for patients such as waste of time, including payment. The aim of this study is to identify the prevalence and causes of canceling surgical procedures, in order to achieve problem solving methods.Materials and Methods: This is a descriptive cross-sectional study. Statistical data regarding all surgical procedures (without sampling performed during 2006 to 2007, were recorded in a checklist. Study variables were identified based on surgical procedures that were canceled during this study. Data was analyzed using SPSS software and statistical analysis tests.Results: Of 4,711 scheduled patients, 510 (10/9% surgical operations were canceled. The highest number of patient candidates for surgical operation was related to gynecology, orthopedic, urology, while the least were related to reconstructive and vascular surgery groups respectively. The most canceled surgical procedures were related to neurosurgical operation 32/4% (68 from 207 cases while the least canceled cases belonged to gynecology 4/4% (48 from 1094 cases.Conclusion: The results of our study showed that 54/2% of canceled cases were preventable. The results of this study and similar studies demonstrate that traditional pre-operative preparation for surgical scheduling, day before surgery is in need of serious consideration. We recommend a fundamental change by discarding traditional methods and creating a new committee including specialized bed or resource groups, monthly management meetings to discuss causes of canceling surgical procedures, in order to reduce its occurrence. Thus, decreasing the rate of canceling surgical wasted, while reducing anxiety in patients and their family. J Mazand Univ Med Sci 2008; 18(65:52-62 (Persian

  6. Treatment outcome and prognostic factor analysis in transplant-eligible Chinese myeloma patients receiving bortezomib-based induction regimens including the staged approach, PAD or VTD

    Directory of Open Access Journals (Sweden)

    Chim Chor

    2012-06-01

    Full Text Available Abstract Background We have reported promising outcomes using a staged approach, in which bortezomib/thalidomide/dexamethasone was used only in 14 patients with suboptimal response to VAD (vincristine/adriamycin/dexamethasone before autologous stem cell transplantation (ASCT. Here we compared the outcomes of the staged approach with frontline PAD (bortezomib/doxorubicin/dexamethasone or VTD (bortezomib/thalidomide/dexamethasone induction, and analysed prognostic factors for outcome. Patients and methods Ninety-one transplant-eligible Chinese patients received three induction regimens prior to ASCT [staged approach (N = 25, PAD (N = 31, VTD (N = 35]. and received thalidomide maintenance for 2 years post-ASCT. Results 43 (47.3% patients had International Staging System (ISS III disease. By an intention-to-treat analysis, the overall CR/nCR rate were 37.4% post-induction, and 62.6% post-ASCT. Five-year overall (OS and event-free (EFS survivals were 66% and 45.1%. There was no difference of the post-induction CR/nCR rate, EFS or OS between patients induced by these three regimens. Moreover, ISS III disease did not affect CR/nCR rates. Multivariate analysis showed that ISS and post-ASCT CR/nCR impacted OS while ISS and post-induction CR/nCR impacted EFS. Conclusions These three induction regimens produced comparable and favorable outcomes in myeloma. The unfavorable outcome of ISS stage III persisted despite upfront/early use of bortezomib. CR/nCR predicted favorable survivals.

  7. Borrelidin Isolated from Streptomyces sp. Inhibited Adipocyte Differentiation in 3T3-L1 Cells via Several Factors Including GATA-Binding Protein 3.

    Science.gov (United States)

    Matsuo, Hirotaka; Kondo, Yoshiyuki; Kawasaki, Takashi; Tokuyama, Shinji; Imamura, Nobutaka

    2015-01-01

    An inhibitor of 3T3-L1 adipocyte differentiation was isolated from Streptomyces sp. TK08330 and identified by spectroscopy as the 18-membered macrolide borrelidin. Treatment with 1.0 μM borrelidin suppressed intracellular lipid accumulation by 80% and inhibited the expression of adipocyte-specific genes. Borrelidin suppressed the mRNA expression of two master regulators of adipocyte differentiation, peroxisome proliferator-activated receptor gamma (PPARγ) and CCAAT/enhancer binding protein (C/EBPα). Studies on well-known upstream regulators of PPARγ revealed that borrelidin down-regulated C/EBPδ mRNA expression but did not affect expression of C/EBPβ. Borrelidin increased mRNA expression of negative regulators of differentiation such as GATA-binding protein (GATA) 3, Krüppel-like factor (KLF) 3 and KLF7, as well as positive regulators, KLF4, KLF6 and KLF15, at early stages of differentiation. To elucidate a primary mediator of borrelidin differentiation inhibitory activity, small interfering RNA (siRNA) transfection experiments were performed. The mRNA expression of PPARγ, which was down-regulated by borrelidin, was not changed by KLF3 and KLF7 siRNA treatment. In contrast, expression of PPARγ in GATA-3 siRNA-treated cells was not significantly different from that of control siRNA-treated cells. Borrelidin significantly inhibited lipid accumulation in control siRNA-treated cells, and treatment with GATA-3 siRNA slightly reduced the inhibitory effect of borrelidin. These results indicate that borrelidin inhibited adipocyte differentiation partially via GATA-3.

  8. Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rγ-/- (NSG mice.

    Directory of Open Access Journals (Sweden)

    Adam C Drake

    Full Text Available Increasing demand for human hematopoietic stem cells (HSCs in clinical and research applications necessitates expansion of HSCs in vitro. Before these cells can be used they must be carefully evaluated to assess their stem cell activity. Here, we expanded cord blood CD34(+ CD133(+ cells in a defined medium containing angiopoietin like 5 and insulin-like growth factor binding protein 2 and evaluated the cells for stem cell activity in NOD-SCID Il2rg(-/- (NSG mice by multi-lineage engraftment, long term reconstitution, limiting dilution and serial reconstitution. The phenotype of expanded cells was characterized by flow cytometry during the course of expansion and following engraftment in mice. We show that the SCID repopulating activity resides in the CD34(+ CD133(+ fraction of expanded cells and that CD34(+ CD133(+ cell number correlates with SCID repopulating activity before and after culture. The expanded cells mediate long-term hematopoiesis and serial reconstitution in NSG mice. Furthermore, they efficiently reconstitute not only neonate but also adult NSG recipients, generating human blood cell populations similar to those reported in mice reconstituted with uncultured human HSCs. These findings suggest an expansion of long term HSCs in our culture and show that expression of CD34 and CD133 serves as a marker for HSC activity in human cord blood cell cultures. The ability to expand human HSCs in vitro should facilitate clinical use of HSCs and large-scale construction of humanized mice from the same donor for research applications.

  9. Temperature-dependence of Weibel-Palade body exocytosis and cell surface dispersal of von Willebrand factor and its propolypeptide.

    Directory of Open Access Journals (Sweden)

    Lindsay Hewlett

    Full Text Available BACKGROUND: Weibel-Palade bodies (WPB are endothelial cell (EC specific secretory organelles containing Von Willebrand factor (VWF. The temperature-dependence of Ca(2+-driven WPB exocytosis is not known, although indirect evidence suggests that WPB exocytosis may occur at very low temperatures. Here we quantitatively analyse the temperature-dependence of Ca(2+-driven WPB exocytosis and release of secreted VWF from the cell surface of ECs using fluorescence microscopy of cultured human ECs containing fluorescent WPBs. PRINCIPAL FINDINGS: Ca(2+-driven WPB exocytosis occurred at all temperatures studied (7-37°C. The kinetics and extent of WPB exocytosis were strongly temperature-dependent: Delays in exocytosis increased from 0.92 s at 37°C to 134.2 s at 7°C, the maximum rate of WPB fusion decreased from 10.0±2.2 s(-1 (37°C to 0.80±0.14 s(-1 (7°C and the fractional extent of degranulation of WPBs in each cell from 67±3% (37°C to 3.6±1.3% (7°C. A discrepancy was found between the reduction in Ca(2+-driven VWF secretion and WPB exocytosis at reduced temperature; at 17°C VWF secretion was reduced by 95% but WPB exocytosis by 75-80%. This discrepancy arises because VWF dispersal from sites of WPB exocytosis is largely prevented at low temperature. In contrast VWF-propolypeptide (proregion dispersal from WPBs, although slowed, was complete within 60-120 s. Novel antibodies to the cleaved and processed proregion were characterised and used to show that secreted proregion more accurately reports the secretion of WPBs at sub-physiological temperatures than assay of VWF itself. CONCLUSIONS: We report the first quantitative analysis of the temperature-dependence of WPB exocytosis. We provide evidence; by comparison of biochemical data for VWF or proregion secretion with direct analysis of WPB exocytosis at reduced temperature, that proregion is a more reliable marker for WPB exocytosis at reduced temperature, where VWF-EC adhesion is increased.

  10. Dynamic Temperature Rise Mechanism and Some Controlling Factors of Wet Clutch Engagement

    Directory of Open Access Journals (Sweden)

    Zhang Zhigang

    2016-01-01

    Full Text Available The friction transmission model of wet clutch is established to analyze the friction transmission mechanism of its engagement. The model is developed by applying both the average flow model and the elastic contact model between the friction disk and separator plate. The key components during wet clutch engagement are the separator plate, friction disk, and lubricant. The one-dimension transient models of heat transfer in radial direction for the three components are built on the basis of the heat transfer theory and the conservation law of energy. The friction transmission model and transient heat transfer models are coupled and solved by using the Runge-Kutta numerical method, and the radial temperature distribution and their detailed parametric study for the three components are conducted separately. The simulation results show that the radial temperature for the three components rises with the increase of radius in engagement. The changes in engagement pressure, lubricant viscosity, friction lining permeability, combined surface roughness RMS, equivalent elasticity modulus, difference between dynamic and static friction coefficients, and lubricant flow have important influence on the temperature rise characteristics. The proposed models can get better understanding of the dynamic temperature rise characteristics of wet clutch engagement.

  11. Modifiable risk factors including sunlight exposure and fish consumption are associated with risk of hypertension in a large representative population from Macau.

    Science.gov (United States)

    Ke, Liang; Ho, Jacky; Feng, Jianzhang; Mpofu, Elias; Dibley, Michael J; Feng, Xiuhua; Van, Florance; Leong, Sokman; Lau, Winne; Lueng, Petra; Kowk, Carrie; Li, Yan; Mason, Rebecca S; Brock, Kaye E

    2014-10-01

    Chinese populations are known to be at risk for vitamin D deficiency, with some evidence that this is due to lack of exposure to sunlight. Vitamin D deficiency and/or low sun exposure have been associated with higher incidence of hypertension in Caucasians. Thus, we investigated these associations in a Chinese population with a high rate of hypertension. From a random household survey of 1410 residents aged ≥18 years, height, weight and blood pressure were measured and demographic, exercise and dietary data were collected, as well as estimated hours of sunlight exposure on weekdays and weekends (in winter and summer). Modifiable predictors of hypertension in these data were lack of sunlight exposure and low intake of fish as well as smoking, obesity and lack of exercise. When investigated in a linear model, sunlight exposure was negatively associated with hypertension (β=-0.072, pexposure per day compared to none was associated with less hypertension (OR=0.6, 95% CI: 0.4-0.8). Similarly, consuming either oily fish or seafood more than four times per week compared to less was also associated with less hypertension (oily fish (OR=0.4, 95% CI: 0.3-0.5); seafood consumption (OR=0.8, 95% CI: 0.7-0.9)). Having daily moderate physical activity compared to none was also associated with a lower risk of hypertension (OR=0.8, 95% CI: 0.7-0.9). In contrast, being obese compared to normal weight and having more than five pack-years of smoking compared to none were associated with a higher risk of hypertension (OR=4.6, 95% CI: 3.7-5.7; OR=1.4, 95% CI: 1.0-1.8, respectively). The major new findings of this study are that more sun exposure and high weekly fish consumption (especially oily fish) may be potentially modifiable independent factors for protecting against risk of hypertension in this population. This article is part of a Special Issue entitled '16th Vitamin D Workshop'. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. Influence of temperature on symptom expression, detection of host factors in virus infected Piper nigrum L.

    Science.gov (United States)

    Umadevi, P; Bhat, A I; Krishnamurthy, K S; Anandaraj, M

    2016-05-01

    Expression of symptoms in black pepper plants (Piper nigrum) infected with Piper yellow mottle virus (PYMoV) vary depending on the season, being high during summer months. Here, we explored the influence of temperature on symptom expression in PYMoV infected P. nigrum. Our controlled environment study revealed increase in virus titer, total proteins, IAA and reducing sugars when exposed to temperature stress. There was change in the 2-D separated protein before and after exposure. The 2-D proteomics LC-MS identified host and viral proteins suggesting virus-host interaction during symptom expression. The analysis as well as detection of host biochemical compounds may help in understanding the detailed mechanisms underlying the viral replication and damage to the crop, and thereby plan management strategies.

  13. On the Controlling Factor of Catalyst Temperature in C3H8-Air Mixture

    Institute of Scientific and Technical Information of China (English)

    Goro ONUMA; Mitsuaki TANABE; Kiyoshi AOKI

    2001-01-01

    Catalytic combustion of propane-air mixture was investigated. Platinum catalysts over a flat stainless steel with y alumina washcoat were employed. The employed burner has three catalysts set parallel to the mixture flow, spaced at an interval of 5, 10 and 15 mm. Both experiment and numerical simulation were made at inlet temperature of 553 K, inlet velocity of 3 to 7 rn/s and equivalence ratio of 0.3 to 0.5. In the numerical simulation, two-dimensional,steady state model was developed to calculate the temperature and species concentration in gas-phase. In this model,chemical reaction on the catalyst surface and that in the gas phase were assumed to occur in three-steps. The numerical results show good agreement with experimental results. It was found that the properties of the catalyst strongly affect the catalyst surface temperature. Especially, the thermal conductivity of catalyst has a great effect,while the emissivity of catalyst has less effect.

  14. Increase of ozone concentrations, its temperature sensitivity and the precursor factor in South China

    Directory of Open Access Journals (Sweden)

    Y. C. Lee

    2014-08-01

    Full Text Available Concerns have been raised about the possible connections between the local and regional photochemical problem and global warming. The current study assesses the trend of ozone in Hong Kong and the Pearl River Delta (PRD in South China and investigates the interannual changes of sensitivity of ozone to air temperature, as well as the trends in regional precursors. Results reveal, at the three monitoring sites from the mid-1990s to 2010, an increase in the mean ozone concentrations from 1.0 to 1.6 µg m−3 per year. The increase occurred in all seasons, with the highest rate in autumn. This is consistent with trends and temperature anomalies in the region. The increase in the sensitivity of ozone to temperature is clearly evident from the correlation between ozone (OMI [Ozone Monitoring Instrument] column amount and surface air temperature (from the Atmospheric Infrared Sounder displayed in the correlation maps for the PRD during the prominently high ozone period of July–September. It is observed to have increased from 2005 to 2010, the latter being the hottest year on record globally. To verify this temporal change in sensitivity, the ground-level trends of correlation coefficients/regression slopes are analysed. As expected, results reveal a statistically significant upward trend over a 14-year period (1997–2010. While the correlation revealed in the correlation maps is in agreement with the corresponding OMI ozone maps when juxtaposed, temperature sensitivity of surface ozone also shows an association with ozone concentration, with R=0.5. These characteristics of ozone sensitivity are believed to have adverse implications for the region. As shown by ground measurements and/or satellite analyses, the decrease in nitrogen oxides (NO2 and NOx in Hong Kong is not statistically significant while NO2 of the PRD has only very slightly changed. However, carbon dioxide has remarkably declined in the whole region. While these observations concerning

  15. Growth, condition factor, and bioenergetics modeling link warmer stream temperatures below a small dam to reduced performance of juvenile steelhead

    Science.gov (United States)

    Sauter, S.T.; Connolly, P.J.

    2010-01-01

    We investigated the growth and feeding performance of juvenile steelhead Oncorhynchus mykiss using field measures and bioenergetics modeling. Juvenile steelhead populations were sampled from mid-June through August 2004 at study sites upstream and downstream of Hemlock Dam. The growth and diet of juvenile steelhead were determined for a warm (summer) and subsequent (late summer) transitional period at each study site. Empirical data on the growth and diet of juvenile steelhead and mean daily temperatures were used in a bioenergetics model to estimate the proportion of maximum consumption achieved by juvenile steelhead by site and period. Modeled estimates of feeding performance were better for juvenile steelhead at the upstream compared to the downstream site during both periods. The median condition factor of juvenile steelhead did not change over the summer at the upstream site, but showed a significant decline over time at the downstream site. A negative trend in median condition factor at the downstream site supported bioenergetics modeling results that suggested the warmer stream temperatures had a negative impact on juvenile steelhead. Bioenergetics modeling predicted a lower feeding performance for juvenile steelhead rearing downstream compared to upstream of Hemlock Dam although food availability appeared to be limited at both study sites during the warm period. Warmer water temperatures, greater diel variation, and change in diel pattern likely led to the reduced feeding performance and reduced growth, which could have affected the overall survival of juvenile steelhead downstream of Hemlock Dam. ?? 2010 by the Northwest Scientific Association.

  16. Theoretical Research on Thermal Shock Resistance of Ultra-High Temperature Ceramics Focusing on the Adjustment of Stress Reduction Factor

    Directory of Open Access Journals (Sweden)

    Daining Fang

    2013-02-01

    Full Text Available The thermal shock resistance of ceramics depends on not only the mechanical and thermal properties of materials, but also the external constraint and thermal condition. So, in order to study the actual situation in its service process, a temperature-dependent thermal shock resistance model for ultra-high temperature ceramics considering the effects of the thermal environment and external constraint was established based on the existing theory. The present work mainly focused on the adjustment of the stress reduction factor according to different thermal shock situations. The influences of external constraint on both critical rupture temperature difference and the second thermal shock resistance parameter in either case of rapid heating or cooling conditions had been studied based on this model. The results show the necessity of adjustment of the stress reduction factor in different thermal shock situations and the limitations of the applicable range of the second thermal shock resistance parameter. Furthermore, the model was validated by the finite element method.

  17. Three-point bending setup for piezoresistive gauge factor measurement of thin-film samples at high temperatures.

    Science.gov (United States)

    Madsen, Nis Dam; Kjelstrup-Hansen, Jakob

    2017-01-01

    We present a new method for measuring the piezoresistive gauge factor of a thin-film resistor based on three-point bending. A ceramic fixture has been designed and manufactured to fit a state-of-the-art mechanical testing apparatus (TA Instruments Q800). The method has been developed to test thin-film samples deposited on silicon substrates with an insulating layer of SiO2. The electrical connections to the resistor are achieved through contacts in the support points. This insures that the influence of the electrical contacts is reduced to a minimum and eliminates wire-bonding or connectors attached to the sample. During measurement, both force and deflection of the sample are recorded simultaneously with the electrical data. The data analysis extracts a precise measurement of the sample thickness (film resistor. This method provides a faster sample evaluation by eliminating an additional sample thickness measurement or alternatively an option for cross checking data. Furthermore, the method implements a full compensation of thermoelectrical effects, which could otherwise lead to significant errors at high temperature. We also discuss the magnitude of the error sources in the setup. The performance of the setup is demonstrated using a titanium nitride thin-film, which is tested up to 400 °C revealing the gauge factor behavior in this temperature span and the temperature coefficient of resistivity.

  18. Study of Inactivation Factors in Low Temperature Surface-wave Plasma Sterilization

    Science.gov (United States)

    Singh, Mrityunjai Kumar; Xu, Lei; Ogino, Akihisa; Nagatsu, Masaaki

    In this study we investigated the low temperature surface-wave plasma sterilization of directly and indirectly exposed Geobacillus stearothermophilus spores with a large-volume microwave plasma device. The air-simulated gas mixture was used to produce the plasma. The water vapor addition to the gas mixture improved the sterilization efficiency significantly. The effect of ultraviolet photons produced along with plasma to inactivate the spores was studied using a separate chamber, which was evacuated to less than one mTorr and was observed that spores were sterilized within 60 min. The scanning electron microscopy images revealed no significant changes in the actual size of the spores with that of untreated spores despite the survival curve shown that the spores were inactivated.

  19. Experimental and theoretical investigations on the singularity of the intensity factor of the current in high temperature superconductors

    Science.gov (United States)

    Zhang, Xingyi; Huang, Yi; Zhou, Jun; Zhou, Youhe

    2013-08-01

    This paper presents experimental and analytical investigations into the distribution of current around a through-edge crack located in an infinitely long cylindrical high temperature superconductor (HTS) on the basis of the Bean model. Current distributions around the crack in the HTS without deformation are obtained by a simple conformal mapping. It is shown that the current is singular at the tip of the crack. An intensity factor of the current is introduced to characterize the singularity, the order of which is equal to -1. Additionally, an experimental verification according to the trapped field distributions around the crack is carried out, and the experimental results show little difference with the theoretical analysis.

  20. Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model.

    Science.gov (United States)

    Moehren, Gisela; Markevich, Nick; Demin, Oleg; Kiyatkin, Anatoly; Goryanin, Igor; Hoek, Jan B; Kholodenko, Boris N

    2002-01-08

    Stimulation of isolated hepatocytes with epidermal growth factor (EGF) causes rapid tyrosine phosphorylation of the EGF receptor (EGFR) and adapter/target proteins, which was monitored with 1 and 2 s resolution at 37, 20, and 4 degrees C. The temporal responses detected for multiple signaling proteins involve both transient and sustained phosphorylation patterns, which change dramatically at low temperatures. To account quantitatively for complex responses, we employed a mechanistic kinetic model of the EGFR pathway, formulated in molecular terms as cascades of protein interactions and phosphorylation and dephosphorylation reactions. Assuming differential temperature dependencies for different reaction groups, such as SH2 and PTB domain-mediated interactions, the EGFR kinase, and the phosphatases, good quantitative agreement was obtained between computer-simulated and measured responses. The kinetic model demonstrates that, for each protein-protein interaction, the dissociation rate constant, k(off), strongly decreases at low temperatures, whereas this decline may or may not be accompanied by a large decrease in the k(on) value. Temperature-induced changes in the maximal activities of the reactions catalyzed by the EGFR kinase were moderate, compared to such changes in the V(max) of the phosphatases. However, strong changes in both the V(max) and K(m) for phosphatases resulted in moderate changes in the V(max)/K(m) ratio, comparable to the corresponding changes in EGFR kinase activity, with a single exception for the receptor phosphatase at 4 degrees C. The model suggests a significant decrease in the rates of the EGF receptor dimerization and its dephosphorylation at 4 degrees C, which can be related to the phase transition in the membrane lipids. A combination of high-resolution experimental monitoring and molecular level kinetic modeling made it possible to quantitatively account for the temperature dependence of the integrative signaling responses.

  1. Factors influencing the formation of histaminol, hydroxytyrosol, tyrosol, and tryptophol in wine: Temperature, alcoholic degree, and amino acids concentration.

    Science.gov (United States)

    Bordiga, M; Lorenzo, C; Pardo, F; Salinas, M R; Travaglia, F; Arlorio, M; Coïsson, J D; Garde-Cerdán, T

    2016-04-15

    The validation of a HPLC-PDA-MS/MS chromatographic method for the quali/quantitative characterization of histaminol, hydroxytyrosol, tyrosol, and tryptophol in wine has been described and discussed. Four standards showed a good linearity with high correlation coefficient values (over 0.9989) and LOD and LOQ were 0.001-0.015 mg/L and 0.004-0.045 mg/L, respectively. Furthermore, this study reported how factors such as temperature, alcoholic degree, and amino acids concentration are able to influence the formation of these four alcohols in Monastrell wines. The quantification values of these alcohols has been detected both at the half and end of alcoholic fermentation, and at the end of malolactic fermentation. In relation to interactions between factors, several significant variations emerged (p ⩽ 0.001). The impact of amino acids supplementation in Monastrell must it has been demonstrated, mainly in regards to histaminol and tryptophol.

  2. Effects of Corticotropin Releasing Factor (CRF on Sleep and Temperature Following Predictable Controllable and Uncontrollable Stress in Mice

    Directory of Open Access Journals (Sweden)

    Laurie eWellman

    2015-07-01

    Full Text Available Corticotropin releasing factor (CRF is a major mediator of central nervous system responses to stressors, including alterations in wakefulness and sleep. However, its role in mediating stress-induced alterations in sleep has not been fully delineated. In this study, we assessed the role of CRF and the non-specific CRF antagonist, astressin (AST, in regulating changes in sleep produced by signaled, escapable shock (SES and signaled inescapable shock (SIS, two stressors that can increase or decrease sleep, respectively. Male BALB/cJ mice were surgically implanted with transmitters (DataSciences ETA10-F20 for recording EEG, activity and core body temperature by telemetry and a cannula for intracerebroventricular microinjections. After baseline (Base sleep recording, mice were presented tones (90 dB, 2 kHz that started 5.0 sec prior to and co-terminated with footshock (0.5 mA; 5.0 sec maximum duration. SES mice (n=9 always received shock but could terminate it by moving to the non-occupied chamber in a shuttlebox. Yoked SIS mice (n=9 were treated identically, but could not alter shock duration. Training with SES or SIS was conducted over two days to stabilize responses. Afterwards, the mice received saline, CRF (0.4 µg (0.42 mM or AST (1.0 µg (1.4 mM prior to SES or SIS. Sleep was analyzed over 20 h post-stress recordings. After administration of saline, REM was significantly greater in SES mice than in SIS mice whereas after CRF or AST, REM was similar in both groups. Total 20 h NREM did not vary across condition or group. However, after administration of saline and CRF, NREM episode duration was significantly decreased, and NREM episode number significantly increased, in SIS mice compared to SES animals. SES and SIS mice showed similar stress induced hyperthermia (SIH across all conditions. These data demonstrate that CRF can mediate stress-induced changes in sleep independently of SIH, an index of hypothalamic-pituitary-adrenal axis activation.

  3. Regression analysis in modeling of air surface temperature and factors affecting its value in Peninsular Malaysia

    Science.gov (United States)

    Rajab, Jasim Mohammed; Jafri, Mohd. Zubir Mat; Lim, Hwee San; Abdullah, Khiruddin

    2012-10-01

    This study encompasses air surface temperature (AST) modeling in the lower atmosphere. Data of four atmosphere pollutant gases (CO, O3, CH4, and H2O) dataset, retrieved from the National Aeronautics and Space Administration Atmospheric Infrared Sounder (AIRS), from 2003 to 2008 was employed to develop a model to predict AST value in the Malaysian peninsula using the multiple regression method. For the entire period, the pollutants were highly correlated (R=0.821) with predicted AST. Comparisons among five stations in 2009 showed close agreement between the predicted AST and the observed AST from AIRS, especially in the southwest monsoon (SWM) season, within 1.3 K, and for in situ data, within 1 to 2 K. The validation results of AST with AST from AIRS showed high correlation coefficient (R=0.845 to 0.918), indicating the model's efficiency and accuracy. Statistical analysis in terms of β showed that H2O (0.565 to 1.746) tended to contribute significantly to high AST values during the northeast monsoon season. Generally, these results clearly indicate the advantage of using the satellite AIRS data and a correlation analysis study to investigate the impact of atmospheric greenhouse gases on AST over the Malaysian peninsula. A model was developed that is capable of retrieving the Malaysian peninsulan AST in all weather conditions, with total uncertainties ranging between 1 and 2 K.

  4. Development of an improved urban emissivity model based on sky view factor for retrieving effective emissivity and surface temperature over urban areas

    Science.gov (United States)

    Yang, Jinxin; Wong, Man Sing; Menenti, Massimo; Nichol, Janet; Voogt, James; Krayenhoff, E. Scott; Chan, P. W.

    2016-12-01

    This study aims to evaluate the effects of urban geometry on retrieval of emissivity and surface temperature in urban areas. An improved urban emissivity model based on sky view factor (IUEM-SVF) was further enhanced to consider all radiance contributions leaving the urban canopy, including (i) emission by all facets within an instantaneous field of view (IFOV); (ii) reflection by all facets of emission from surrounding facets; and (iii) propagation of emitted and reflected radiation with multiple reflections (scattering) within a complex 3D array of urban objects. The effective emissivity derived from IUEM-SVF was evaluated with a microscale radiative transfer and energy balance model: Temperatures of Urban Facets in 3-D (TUF-3D). IUEM-SVF performs well when urban facets have uniform emissivity and temperature; e.g., root mean square deviations (RMSD) are less than 0.005 when material emissivity is larger than 0.80 (ɛ ⩾ 0.80). However, when material emissivities are variable within the observed target, differences of effective emissivity between IUEM-SVF and TUF-3D become larger, e.g., RMSD of 0.010. When the effect of geometry is not considered and a mixed pixel emissivity is defined, the difference is even much larger (i.e. 0.02) and this difference increases with the decrease of sky view factor. Thus, the geometry effect should be considered in the determination of effective emissivity. Effective emissivity derived from IUEM-SVF was used to retrieve urban surface temperature from a nighttime ASTER thermal infrared image. Promising results were achieved in comparison with standard LST products retrieved with the Temperature and Emissivity Separation (TES) algorithm. IUEM-SVF shows promise as a means to improve the accuracy of urban surface temperature retrieval. The effect of thermal heterogeneity on the effective emissivity was also evaluated by TUF-3D, and results show that the thermal heterogeneity cannot be neglected since the RMSD between the effective

  5. Large-scale stress factors affecting coral reefs: open ocean sea surface temperature and surface seawater aragonite saturation over the next 400 years

    Science.gov (United States)

    Meissner, K. J.; Lippmann, T.; Sen Gupta, A.

    2012-06-01

    One-third of the world's coral reefs have disappeared over the last 30 years, and a further third is under threat today from various stress factors. The main global stress factors on coral reefs have been identified as changes in sea surface temperature (SST) and changes in surface seawater aragonite saturation (Ωarag). Here, we use a climate model of intermediate complexity, which includes an ocean general circulation model and a fully coupled carbon cycle, in conjunction with present-day observations of inter-annual SST variability to investigate three IPCC representative concentration pathways (RCP 3PD, RCP 4.5, and RCP 8.5), and their impact on the environmental stressors of coral reefs related to open ocean SST and open ocean Ωarag over the next 400 years. Our simulations show that for the RCP 4.5 and 8.5 scenarios, the threshold of 3.3 for zonal and annual mean Ωarag would be crossed in the first half of this century. By year 2030, 66-85% of the reef locations considered in this study would experience severe bleaching events at least once every 10 years. Regardless of the concentration pathway, virtually every reef considered in this study (>97%) would experience severe thermal stress by year 2050. In all our simulations, changes in surface seawater aragonite saturation lead changes in temperatures.

  6. Size-resolved polycyclic aromatic hydrocarbon emission factors from on-road gasoline and diesel vehicles: temperature effect on the nuclei-mode.

    Science.gov (United States)

    Eiguren-Fernandez, Arantzazu; Miguel, Antonio H

    2012-03-06

    Motor vehicles are a major source of polycyclic aromatic hydrocarbon (PAH) emissions in urban areas. Motor vehicle emission control strategies have included improvements in engine design, exhaust emission control, and fuel reformulation. Therefore, an updated assessment of the effects of the shifts in fuels and vehicle technologies on PAH vehicular emission factors (EFs) is needed. We have evaluated the effects of ambient temperature on the size-resolved EFs of nine US EPA Priority Pollutant PAH, down to 10 nm diameter, from on-road California gasoline light-duty vehicles with spark ignition (SI) and heavy-duty diesels with compression ignition (CI) in summer 2004 and winter 2005. During the winter, for the target PAH with the lowest subcooled equilibrium vapor pressure --benzo[a]pyrene, benzo[ghi]perylene, and indeno[1,2,3-cd]pyrene-- the mass in the nucleation mode, defined here as particles with dp <32 nm, ranged between 14 and 38% for SI vehicles and 29 and 64% for CI vehicles. Our observations of the effect of temperature on the mass of PAH in the nucleation mode are similar to the observed effect of temperature on the number concentration of diesel exhaust particles in the nucleation mode in a previous report.

  7. Collaborative Group on Hormonal Factors in Breast cancer: Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83000 women with breast cancer from 16 countries

    NARCIS (Netherlands)

    Beral, V.; Bull, D.; Doll, R.; Peto, R.; Reeves, G.; van den Brandt, P.A.; Goldbohm, R.A.

    2004-01-01

    Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83?000 women with breast cancer from 16 countries. Beral V, Bull D, Doll R, Peto R, Reeves G; Collaborative Group on Hormonal Factors in Breast Cancer. BACKGROUND: The Collaborative Group on Hormo

  8. Collaborative Group on Hormonal Factors in Breast cancer: Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83000 women with breast cancer from 16 countries

    NARCIS (Netherlands)

    Beral, V.; Bull, D.; Doll, R.; Peto, R.; Reeves, G.; van den Brandt, P.A.; Goldbohm, R.A.

    2004-01-01

    Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83?000 women with breast cancer from 16 countries. Beral V, Bull D, Doll R, Peto R, Reeves G; Collaborative Group on Hormonal Factors in Breast Cancer. BACKGROUND: The Collaborative Group on

  9. Current-oscillator correlation and Fano factor spectrum of quantum shuttle with finite bias voltage and temperature.

    Science.gov (United States)

    Lai, Wenxi; Cao, Yunshan; Ma, Zhongshui

    2012-05-01

    A general master equation is derived to describe an electromechanical single-dot transistor in the Coulomb blockade regime. In the equation, Fermi distribution functions in the two leads are taken into account, which allows one to study the system as a function of bias voltage and temperature of the leads. Furthermore, we treat the coherent interaction mechanism between electron tunneling events and the dynamics of excited vibrational modes. Stationary solutions of the equation are numerically calculated. We show that current through the oscillating island at low temperature appears to have step-like characteristics as a function of the bias voltage and the steps depend on the mean phonon number of the oscillator. At higher temperatures the current steps would disappear and this event is accompanied by the emergence of thermal noise of the charge transfer. When the system is mainly in the ground state, the zero frequency Fano factor of current manifests sub-Poissonian noise and when the system is partially driven into its excited states it exhibits super-Poissonian noise. The difference in the current noise would almost be removed for the situation in which the dissipation rate of the oscillator is much larger than the bare tunneling rates of electrons.

  10. Factors affecting the wettability of different surface materials with vegetable oil at high temperatures and its relation to cleanability

    DEFF Research Database (Denmark)

    Ashokkumar, Saranya; Adler-Nissen, Jens; Møller, Per

    2012-01-01

    materials investigated include stainless steel (reference), PTFE (polytetrafluoroethylene), silicone, quasicrystalline (Al, Fe, Cr) and ceramic coatings: zirconium oxide (ZrO2), zirconium nitride (ZrN) and titanium aluminum nitride (TiAlN). The ceramic coatings were deposited on stainless steel with two...... different levels of roughness. The cosine of the contact angle of olive oil on different surface materials rises linearly with increasing temperature. Among the materials analyzed, polymers (PTFE, silicone) gave the lowest cosθ values. Studies of the effect of roughness and surface flaws on wettability...

  11. Temperature-related risk factors associated with the colonization of broiler-chicken flocks with Campylobacter spp. in Iceland, 2001-2004

    Science.gov (United States)

    Our objective was to identify temperature-related risk factors associated with the colonization of broiler-chicken flocks with Campylobacter spp. in Iceland, with an underlying assumption that at minimum ambient temperatures, flies (Musca domestica) play a role in the epidemiology and seasonality of...

  12. Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6.

    Science.gov (United States)

    Liu, Wan-Ju; Reece-Hoyes, John S; Walhout, Albertha J M; Eisenmann, David M

    2014-05-13

    Hox genes encode master regulators of regional fate specification during early metazoan development. Much is known about the initiation and regulation of Hox gene expression in Drosophila and vertebrates, but less is known in the non-arthropod invertebrate model system, C. elegans. The C. elegans Hox gene lin-39 is required for correct fate specification in the midbody region, including the Vulval Precursor Cells (VPCs). To better understand lin-39 regulation and function, we aimed to identify transcription factors necessary for lin-39 expression in the VPCs, and in particular sought factors that initiate lin-39 expression in the embryo. We used the yeast one-hybrid (Y1H) method to screen for factors that bound to 13 fragments from the lin-39 region: twelve fragments contained sequences conserved between C. elegans and two other nematode species, while one fragment was known to drive reporter gene expression in the early embryo in cells that generate the VPCs. Sixteen transcription factors that bind to eight lin-39 genomic fragments were identified in yeast, and we characterized several factors by verifying their physical interactions in vitro, and showing that reduction of their function leads to alterations in lin-39 levels and lin-39::GFP reporter expression in vivo. Three factors, the orphan nuclear hormone receptor NHR-43, the hypodermal fate regulator LIN-26, and the GATA factor ELT-6 positively regulate lin-39 expression in the embryonic precursors to the VPCs. In particular, ELT-6 interacts with an enhancer that drives GFP expression in the early embryo, and the ELT-6 site we identified is necessary for proper embryonic expression. These three factors, along with the factors ZTF-17, BED-3 and TBX-9, also positively regulate lin-39 expression in the larval VPCs. These results significantly expand the number of factors known to directly bind and regulate lin-39 expression, identify the first factors required for lin-39 expression in the embryo, and hint at a

  13. Screening of Fungi for Biological Control of a Triatomine Vector of Chagas Disease: Temperature and Trypanosome Infection as Factors

    Science.gov (United States)

    Garcia, Aline R. M.; Rocha, Adriana de Paula; Moreira, Camila C.; Rocha, Silma L.; Guarneri, Alessandra A.; Elliot, Simon L.

    2016-01-01

    Entomopathogenic fungi have been investigated as an alternative tool for controlling various insects, including triatomine vectors of the protozoan Trypanosoma cruzi, the etiological agent of Chagas disease. Here we tested the pathogenicity and virulence of ten isolates of the fungi Metarhizium spp. and Beauveria bassiana against Rhodnius prolixus and found all of the isolates to be virulent. We used two isolates (URPE-11 Metarhizium anisopliae and ENT-1 Beauveria bassiana) for further screening based on their prolific sporulation in vitro (an important property of fungal biopesticides). We characterized their virulences in a dose-response experiment and then examined virulence across a range of temperatures (21, 23, 27 and 30°C). We found isolate ENT-1 to maintain higher levels of virulence over these temperatures than URPE-11. We therefore used B. bassiana ENT-1 in the final experiment in which we examined the survival of insects parasitized with T. cruzi and then infected with this fungus (once again over a range of temperatures). Contrary to our expectations, the survival of insects challenged with the pathogenic fungus was greater when they had previously been infected with the parasite T. cruzi than when they had not (independent of temperature). We discuss these results in terms of aspects of the biologies of the three organisms. In practical terms, we concluded that, while we have fungal isolates of potential interest for development as biopesticides against R. prolixus, we have identified what could be a critical problem for this biological tool: the parasite T. cruzi appears to confer a measure of resistance to the insect against the potential biopesticide agent so use of this fungus as a biopesticide could lead to selection for vector competence. PMID:27855217

  14. Variations of karst underground air temperature induced by various factors (Cave of Županova jama, Central Slovenia)

    Science.gov (United States)

    Ravbar, Natasa; Kosutnik, Jure

    2014-04-01

    On the basis of air temperature ( T) monitoring, basic statistical and time series analysis was employed to evaluate thermal states of cave atmosphere variations. Long-term, seasonal and event comparative analysis as well as spectral and cross-correlation analysis was conducted. The results show the relative stability of air T in the isolated part of the cave, whereas variable air T was observed in the parts close to entrances and the surface. The distinctive seasonality in this part of the cave demonstrates that air convection is a driving force for the heat exchange between the cave and the surrounding environment. External air T and heat conducted through the rock walls are also an important factor influencing the cave climate, while heat released by the ice deposit and by water infiltrating through the cave ceiling has a negligible effect. Occasional irregular variations in daily patterns are caused by human impact.

  15. High Q-factor Sapphire Whispering Gallery Mode Microwave Resonator at Single Photon Energies and milli-Kelvin Temperatures

    CERN Document Server

    Creedon, Daniel L; Farr, Warrick; Martinis, John M; Duty, Timothy L; Tobar, Michael E

    2011-01-01

    The microwave properties of a crystalline sapphire dielectric whispering gallery mode resonator have been measured at very low excitation strength (E/hf=1) and low temperatures (T = 30 mK). The measurements were sensitive enough to observe saturation due to a highly detuned electron spin resonance, which limited the loss tangent of the material to about 2e-8 measured at 13.868 and 13.259 GHz. Small power dependent frequency shifts were also measured which correspond to an added magnetic susceptibility of order 1e-9. This work shows that quantum limited microwave resonators with Q-factors > 1e8 are possible with the implementation of a sapphire whispering gallery mode system.

  16. Ambient temperature signalling in plants.

    Science.gov (United States)

    Wigge, Philip A

    2013-10-01

    Plants are exposed to daily and seasonal fluctuations in temperature. Within the 'ambient' temperature range (about 12-27°C for Arabidopsis) temperature differences have large effects on plant growth and development, disease resistance pathways and the circadian clock without activating temperature stress pathways. It is this developmental sensing and response to non-stressful temperatures that will be covered in this review. Recent advances have revealed key players in mediating temperature signals. The bHLH transcription factor PHYTOCHROME INTERACTING FACTOR4 (PIF4) has been shown to be a hub for multiple responses to warmer temperature in Arabidopsis, including flowering and hypocotyl elongation. Changes in chromatin state are involved in transmitting temperature signals to the transcriptome. Determining the precise mechanisms of temperature perception represents an exciting goal for the field.

  17. Temperature-dependent rotational relaxation in a viscous alkane: Interplay of shape factor and boundary condition on molecular rotation

    Science.gov (United States)

    Dutt, G. B.; Sachdeva, A.

    2003-05-01

    Rotational relaxation of three organic solutes, coumarin 6 (C6), 2,5-dimethyl-1, 4-dioxo3,6-diphenylpyrrolo[3,4-c]pyrrole (DMDPP), and nile red (NR), that are similar in size but distinct in shape has been studied in a nonpolar solvent, squalane as a function of temperature to find out how the mechanical friction experienced by the solute molecule is influenced by its shape. It has been observed that C6 rotates slowest followed by NR and DMDPP. The results are analyzed using Stokes-Einstein-Debye (SED) hydrodynamic theory and also quasihydrodynamic theories of Gierer and Wirtz, and Dote, Kivelson, and Schwartz. Analysis of the data using the SED theory reveals that the measured reorientation times of C6 and DMDPP follow subslip behavior whereas those of NR are found to match slip predictions. While no single model could mimic the observed trend even in a qualitative manner, the reorientation times of C6 and DMDPP when normalized by their respective shape factors and boundary-condition parameters can be scaled on a common curve over the entire range of temperature studied. The probable reasons for the distinctive rotational behavior of NR as compared to C6 and DMDPP are explained in terms of its molecular shape and how this in turn influences the boundary-condition parameter are discussed.

  18. The effect of preparation factors on the structural and catalytic properties of mesoporous nanocrystalline iron-based catalysts for high temperature water gas shift reaction

    Energy Technology Data Exchange (ETDEWEB)

    Meshkani, Fereshteh; Rezaei, Mehran [University of Kashan, Kashan (Iran, Islamic Republic of)

    2015-07-15

    A systematic study was done on the effect of preparation factors on the structural and catalytic properties of mesoporous nanocrystalline iron-based catalysts in high temperature water gas shift reaction. The catalysts were prepared by coprecipitation method, and the effect of the main preparation factors (pH, refluxing temperature, refluxing time, concentration of the precursors solution) was studied. The catalysts were characterized by powder X-ray diffraction (XRD), N{sub 2} adsorption (BET), Temperature programmed reduction (TPR), transmission and scanning electron microscopies (TEM, SEM) techniques. The results revealed that the preparation factors affected the textural and catalytic properties of the Fe-Cr-Cu catalyst. The results showed that the prepared catalyst with the highest activity showed higher specific surface area compared to commercial catalyst and consequently exhibited higher activity in high temperature water gas shift reaction. The TEM analysis showed a nanostructure for this sample with crystallite size less than 20 nm.

  19. Metabolic fingerprinting of gilthead seabream (Sparus aurata liver to track interactions between dietary factors and seasonal temperature variations

    Directory of Open Access Journals (Sweden)

    Tomé S. Silva

    2014-08-01

    Full Text Available Farmed gilthead seabream is sometimes affected by a metabolic syndrome, known as the “winter disease”, which has a significant economic impact in the Mediterranean region. It is caused, among other factors, by the thermal variations that occur during colder months and there are signs that an improved nutritional status can mitigate the effects of this thermal stress. For this reason, a trial was undertaken where we assessed the effect of two different diets on gilthead seabream physiology and nutritional state, through metabolic fingerprinting of hepatic tissue. For this trial, four groups of 25 adult gilthead seabream were reared for 8 months, being fed either with a control diet (CTRL, low-cost commercial formulation or with a diet called “Winter Feed” (WF, high-cost improved formulation. Fish were sampled at two time-points (at the end of winter and at the end of spring, with liver tissue being taken for FT-IR spectroscopy. Results have shown that seasonal temperature variations constitute a metabolic challenge for gilthead seabream, with hepatic carbohydrate stores being consumed over the course of the inter-sampling period. Regarding the WF diet, results point towards a positive effect in terms of performance and improved nutritional status. This diet seems to have a mitigating effect on the deleterious impact of thermal shifts, confirming the hypothesis that nutritional factors can affect the capacity of gilthead seabream to cope with seasonal thermal variations and possibly contribute to prevent the onset of “winter disease”.

  20. A Review of Temperature, pH, and Other Factors that Influence the Survival of Salmonella in Mayonnaise and Other Raw Egg Products

    Directory of Open Access Journals (Sweden)

    Thilini Piushani Keerthirathne

    2016-11-01

    Full Text Available Salmonellosis is one of the main causes of foodborne illnesses worldwide, with outbreaks predominately linked to contamination of eggs and raw egg products, such as mayonnaise. This review explores previous studies that have investigated Salmonella control mechanisms utilized in the production of raw egg mayonnaise and other food products. Apart from the use of pasteurized eggs, the main control mechanism identified is the pH of the raw egg products, which plays an important role in the consistency and stability while affecting the survival of Salmonella spp. However, currently there is no consensus regarding the critical pH limit for the control of Salmonella. The effectiveness of pH as a control mechanism is influenced by the type of acid used, with the effectiveness of lemon juice compared with vinegar highly debated. Additionally, Salmonella susceptibility to pH stresses may also be influenced by storage temperature (in some studies refrigeration temperatures protected Salmonella spp. from acidulants and is further complicated by the development of Salmonella cross-tolerance-induced responses, pH homeostasis achieved by the cellular antiport and symport systems, and acid tolerance response (ATR. These mechanisms all provide Salmonella with an added advantage to ensure survival under various pH conditions. Other confounding factors include the fat content, and the addition of NaCl, garlic and plant essential oils (PEOs from mint, cinnamon, cardamom and clove.

  1. A Review of Temperature, pH, and Other Factors that Influence the Survival of Salmonella in Mayonnaise and Other Raw Egg Products.

    Science.gov (United States)

    Keerthirathne, Thilini Piushani; Ross, Kirstin; Fallowfield, Howard; Whiley, Harriet

    2016-11-18

    Salmonellosis is one of the main causes of foodborne illnesses worldwide, with outbreaks predominately linked to contamination of eggs and raw egg products, such as mayonnaise. This review explores previous studies that have investigated Salmonella control mechanisms utilized in the production of raw egg mayonnaise and other food products. Apart from the use of pasteurized eggs, the main control mechanism identified is the pH of the raw egg products, which plays an important role in the consistency and stability while affecting the survival of Salmonella spp. However, currently there is no consensus regarding the critical pH limit for the control of Salmonella. The effectiveness of pH as a control mechanism is influenced by the type of acid used, with the effectiveness of lemon juice compared with vinegar highly debated. Additionally, Salmonella susceptibility to pH stresses may also be influenced by storage temperature (in some studies refrigeration temperatures protected Salmonella spp. from acidulants) and is further complicated by the development of Salmonella cross-tolerance-induced responses, pH homeostasis achieved by the cellular antiport and symport systems, and acid tolerance response (ATR). These mechanisms all provide Salmonella with an added advantage to ensure survival under various pH conditions. Other confounding factors include the fat content, and the addition of NaCl, garlic and plant essential oils (PEOs) from mint, cinnamon, cardamom and clove.

  2. A Review of Temperature, pH, and Other Factors that Influence the Survival of Salmonella in Mayonnaise and Other Raw Egg Products

    Science.gov (United States)

    Keerthirathne, Thilini Piushani; Ross, Kirstin; Fallowfield, Howard; Whiley, Harriet

    2016-01-01

    Salmonellosis is one of the main causes of foodborne illnesses worldwide, with outbreaks predominately linked to contamination of eggs and raw egg products, such as mayonnaise. This review explores previous studies that have investigated Salmonella control mechanisms utilized in the production of raw egg mayonnaise and other food products. Apart from the use of pasteurized eggs, the main control mechanism identified is the pH of the raw egg products, which plays an important role in the consistency and stability while affecting the survival of Salmonella spp. However, currently there is no consensus regarding the critical pH limit for the control of Salmonella. The effectiveness of pH as a control mechanism is influenced by the type of acid used, with the effectiveness of lemon juice compared with vinegar highly debated. Additionally, Salmonella susceptibility to pH stresses may also be influenced by storage temperature (in some studies refrigeration temperatures protected Salmonella spp. from acidulants) and is further complicated by the development of Salmonella cross-tolerance-induced responses, pH homeostasis achieved by the cellular antiport and symport systems, and acid tolerance response (ATR). These mechanisms all provide Salmonella with an added advantage to ensure survival under various pH conditions. Other confounding factors include the fat content, and the addition of NaCl, garlic and plant essential oils (PEOs) from mint, cinnamon, cardamom and clove. PMID:27869756

  3. B{sub c}B{sub c}J/ψ vertex form factor at finite temperature in the framework of QCD sum rules approach

    Energy Technology Data Exchange (ETDEWEB)

    Yazici, E.; Sundu, H.; Veliev, E.V. [Kocaeli University, Department of Physics, Izmit (Turkey)

    2016-02-15

    The strong form factor of the B{sub c}B{sub c}J/ψ vertex is calculated in the framework of the QCD sum rules method at finite temperature. Taking into account additional operators appearing at finite temperature, a thermal Wilson expansion is obtained and QCD sum rules are derived. While increasing the temperature, the strong form factor remains unchanged up to T ≅ 100 MeV but slightly increases after this point. After T ≅ 160 MeV, the form factor suddenly decreases up to T ≅ 170 MeV. The obtained result of the coupling constant by fitting the form factor at Q{sub 2} = -m{sup 2}{sub offshell} at T = 0 is in a very good agreement with the QCD sum rules calculations in the case of vacuum. Our prediction can be checked in future experiments. (orig.)

  4. The effects of different nano particles of Al2O3 and Ag on the MHD nano fluid flow and heat transfer in a microchannel including slip velocity and temperature jump

    Science.gov (United States)

    Karimipour, Arash; D'Orazio, Annunziata; Shadloo, Mostafa Safdari

    2017-02-01

    The forced convection of nanofluid flow in a long microchannel is studied numerically according to the finite volume approach and by using a developed computer code. Microchannel domain is under the influence of a magnetic field with uniform strength. The hot inlet nanofluid is cooled by the heat exchange with the cold microchannel walls. Different types of nanoparticles such as Al2O3 and Ag are examined while the base fluid is considered as water. Reynolds number are chosen as Re=10 and Re=100. Slip velocity and temperature jump boundary conditions are simulated along the microchannel walls at different values of slip coefficient for different amounts of Hartmann number. The investigation of magnetic field effect on slip velocity and temperature jump of nanofluid is presented for the first time. The results are shown as streamlines and isotherms; moreover the profiles of slip velocity and temperature jump are drawn. It is observed that more slip coefficient corresponds to less Nusselt number and more slip velocity especially at larger Hartmann number. It is recommended to use Al2O3-water nanofluid instead of Ag-water to increase the heat transfer rate from the microchannel walls at low values of Re. However at larger amounts of Re, the nanofluid composed of nanoparticles with higher thermal conductivity works better.

  5. High fill factor polymer solar cells incorporating a low temperature solution processed WO{sub 3} hole extraction layer

    Energy Technology Data Exchange (ETDEWEB)

    Stubhan, Tobias; Li, Ning; Matt, Gebhard J. [Institute of Materials for Electronics and Energy Technology (I-MEET), Friedrich-Alexander-University Erlangen-Nuremberg, Martensstrasse 7, 91058 Erlangen (Germany); Luechinger, Norman A.; Halim, Samuel C. [Nanograde Llc., Wolfgang-Pauli-Strasse, P/O Box 239, 8093 Zurich (Switzerland); Brabec, Christoph J. [Institute of Materials for Electronics and Energy Technology (I-MEET), Friedrich-Alexander-University Erlangen-Nuremberg, Martensstrasse 7, 91058 Erlangen (Germany); Bavarian Center for Applied Energy Research (ZAE Bayern), Haberstrasse 2a, 91058 Erlangen (Germany)

    2012-12-15

    We demonstrate solution-processed tungsten trioxide (WO{sub 3}) incorporated as hole extraction layer (HEL) in polymer solar cells (PSCs) with active layers comprising either poly(3-hexylthiophene) (P3HT) or poly[(4,4'-bis(2-ethylhexyl)dithieno[3,2-b:2',3'-d]silole)-2,6-diyl-alt-(4,7-bis(2-thienyl)-2,1,3-benzothiadiazole)-5,50-diyl] (Si-PCPDTBT) mixed with a fullerene derivative. The WO{sub 3} layers are deposited from an alcohol-based, surfactant-free nanoparticle solution. A short, low-temperature (80 C) annealing is sufficient to result in fully functional films without the need for an oxygen-plasma treatment. This allows the application of the WO{sub 3} buffer layer in normal as well as inverted architecture solar cells. Normal architecture devices based on WO{sub 3} HELs show comparable performance to the PEDOT:PSS reference devices with slightly better fill factors and open circuit voltages. Very high shunt resistances (over 1 M{Omega} cm{sup 2}) and excellent diode rectification underline the charge selectivity of the solution-processed WO{sub 3} layers. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  6. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang

    2016-06-07

    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  7. Investigating students’ attitude towards the importance of factors included in the teaching evaluation forms of School of Public Health of Shahid Sadoughi University of Medical Sciences in 2010-2011

    Directory of Open Access Journals (Sweden)

    M. H Dehghani Tafti

    2012-11-01

    Full Text Available Introduction: students’ attitudes about teaching methodology have been widely recognised as a valid tool of evaluating teaching activities of faculty members. This study aims to determine the importance of the factors included in the teaching evaluation, from the students’ point of view. Methods: This is a cross-sectional study. Using a random cluster sampling, 332 students of the school of public health of Shahid Sadoughi University were selected .To collect data, a questionnaire containing three partswere used. These were demographic items, teachers’ evaluation (14 items and self-evaluation (4 items. Results: The students (80% scoredpersonal characteristics more. Among different fields of study, those studying occupational health scored the factorsless than others, and those studying at masters level scored them more than others.   The results indicated that there are significant correlation between age, marital status, and employment status of the students and the total average score.   The students scored the self-evaluation items more than 60%, There was a significant correlation between the average scores of evaluation and self-evaluation items. The students at bachelor level scored the factor more than masters students. Conclusion: The students’ focus on personal characteristics of teachers was remarkable. There is a need to revise the process of academics’ recruitment based on these findings. There is also a need to review the items included in evaluation forms of the school.

  8. Visual Impairment, Including Blindness

    Science.gov (United States)

    ... Who Knows What? Survey Item Bank Search for: Visual Impairment, Including Blindness Links updated, April 2017 En ... doesn’t wear his glasses. Back to top Visual Impairments in Children Vision is one of our ...

  9. Analysis of the Temperature Effect on the Infinite Multiplication Factor for HEU-UAl4 and LEU-UO2 Lattices of GHARR-1

    Directory of Open Access Journals (Sweden)

    E. Alhassan

    2011-03-01

    Full Text Available The purpose of the study is to analyze the temperature effect on the infinite multiplication factor for light water moderated High Enriched Uranium (HEU-UAl4 and Low Enriched Uranium (LEU-UO2 lattices of the Ghana Research Reactor-1 (GHARR-1. To quantify the contribution of each component of the infinite multiplication factor with respect to temperature within the 20 to 140ºC range, cell calculations were performed for the two MNSR typical lattices: the 90.2% enriched HEU-UAl4 and 12.6% enriched LEU- UO2 proposed fuel of the Ghana Research Reactor-1 (GHARR-1 using SCUBA, a locally developed FORTRAN 95 code for the calculations and analysis of temperature coefficients of GHARR-1. It was observed that at the beginning of life of the core, the temperature coefficient of the resonance escape probability and that of the thermal utilization factor, contributed significantly to the negative temperature coefficient of the infinite multiplication factor obtained for both fuels.

  10. Effects of dislocations on small signal high frequency hot electron mobility in n-GaN at low and high temperatures under high magnetic fields including hot phonon effect

    Energy Technology Data Exchange (ETDEWEB)

    Chakraborty, A., E-mail: juimaha@yahoo.co [Department of Electronics and Telecommunication Engineering, Jadavpur University, Kolkata (India); Sarkar, C.K. [Department of Electronics and Telecommunication Engineering, Jadavpur University, Kolkata (India)

    2011-04-01

    The small signal high-frequency ac mobility of hot electrons in n-GaN in the extreme quantum limit at low- and high-temperatures has been calculated considering the non-equilibrium phonon distribution as well as the thermal phonon distributions. The energy loss rate has been calculated considering the dominance of the piezo electric coupling scattering and the polar optical phonon scattering while the momentum loss rate has been calculated considering the acoustic phonon scattering via deformation potential and the piezo electric coupling and the dislocation scattering.

  11. Factors affecting ion kinetic temperature, number density, and containment time in the NASA Lewis bumpy-torus plasma

    Science.gov (United States)

    Roth, J. R.

    1977-01-01

    The degree of toroidal symmetry of the plasma, the number of midplane electrode rings, the configuration of electrode rings, and the location of the diagnostic instruments with respect to the electrode rings used to generate the plasma are discussed. Impurities were deliberately introduced into the plasma, and the effects of the impurity fraction on ion kinetic temperature and electron number density were observed. It is concluded that, if necessary precautions are taken, the plasma communicates extremely well along the magnetic field lines and displays a high degree of symmetry from sector to sector for a wide range of electrode ring configurations and operating conditions. Finally, some characteristic data taken under nonoptimized conditions are presented, which include the highest electron number density and the longest particle containment time (1.9 msec) observed. Also, evidence from a paired comparison test is presented which shows that the electric field acting along the minor radius of the toroidal plasma improves the plasma density and the calculated containment time more than an order of magnitude if the electric field points inward, relative to the values observed when it points (and pushes ions) radially outward.

  12. High Temperature Induces Expression of Tobacco Transcription Factor NtMYC2a to Regulate Nicotine and JA Biosynthesis

    Directory of Open Access Journals (Sweden)

    Liming Yang

    2016-10-01

    Full Text Available Environmental stress elevates the level of jasmonic acid (JA and activates the biosynthesis of nicotine and related pyridine alkaloids in tobacco (Nicotiana tabacum L. by up-regulating the expression of putrescine N-methyltransferase 1 (NtPMT1, which encodes a putrescine N-methyl transferase that catalyzes nicotine formation. The JA signal suppressor JASMONATE ZIM DOMAIN 1 (NtJAZ1 and its target protein, NtMYC2a, also regulate nicotine biosynthesis; however, how these proteins interact to regulate abiotic-induced nicotine biosynthesis is poorly understood. In this study, we found that high-temperature (HT treatment activated transcription of NtMYC2a, which subsequently stimulated the transcription of genes associated with JA biosynthesis, including Lipoxygenase (LOX, Allene oxide synthase (AOS, Allene oxide cyclase (AOC, and 12-oxophytodienodate reductase (OPR. Overexpression of NtMYC2a increased nicotine biosynthesis by enhancing its binding to the promoter of NtPMT1. Overexpression of either NtJAZ1 or proteasome-resistant NtJAZ1∆C suppressed nicotine production under normal conditions, but overexpression only of the former resulted in low levels of nicotine under HT treatment. These data suggest that HT induces NtMYC2a accumulation through increased transcription to activate nicotine synthesis; meanwhile, HT-induced NtMYC2a can activate JA synthesis to promote additional NtMYC2a activity by degrading NtJAZ1 at the post-transcriptional level.

  13. Analytic device including nanostructures

    KAUST Repository

    Di Fabrizio, Enzo M.

    2015-07-02

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  14. Gas-multiplication factor of a proportional counter operated at low temperature described with the Diethorn, Rose-Korff and townsend expressions

    Energy Technology Data Exchange (ETDEWEB)

    Fukumura, Kazuko; Nakanishi, Akio; Kobayashi, Takayuki [Shiga Univ. of Medical Science, Otsu (Japan)

    1996-07-01

    In the present work, the gas-multiplication factor is expressed with the Rose-Korff and Townsend methods as well as with the Diethorn method. A proportional counter with helium or neon works only at low temperature. This is discussed in terms of the number of electrons emitted when an ion is neutralized at the cathode of the counter. (J.P.N.)

  15. Effect of Temperature-Force Factors and Concentrator Shape on Impact Fracture Mechanisms of 17Mn1Si Steel

    Directory of Open Access Journals (Sweden)

    S. V. Panin

    2017-01-01

    Full Text Available The influence of the notch shape on the impact fracture of 17Mn1Si steel is investigated at different temperatures with the focus placed on the low-temperature behavior. An approach towards fracture characterization has been suggested based on the description of elastic-plastic deformation of impact loaded specimens on the stage of crack initiation and growth at ambient and lower temperatures. The analysis of the impact loading diagrams and fracture energy values for the pipe steel 17Mn1Si revealed the fracture mechanisms depending on the notch shape. It was found that the testing temperature reduction played a decisive role in plastic strain localization followed by dynamic fracture of the specimens with differently shaped notches. A classification of fracture macro- and microscopic mechanisms for differently notched specimens tested at different temperatures was proposed which enabled a self-consistent interpretation of impact test results.

  16. Kinetics of the reaction of the heaviest hydrogen atom with H2, the 4Heμ + H2 → 4HeμH + H reaction: experiments, accurate quantal calculations, and variational transition state theory, including kinetic isotope effects for a factor of 36.1 in isotopic mass.

    Science.gov (United States)

    Fleming, Donald G; Arseneau, Donald J; Sukhorukov, Oleksandr; Brewer, Jess H; Mielke, Steven L; Truhlar, Donald G; Schatz, George C; Garrett, Bruce C; Peterson, Kirk A

    2011-11-14

    The neutral muonic helium atom (4)Heμ, in which one of the electrons of He is replaced by a negative muon, may be effectively regarded as the heaviest isotope of the hydrogen atom, with a mass of 4.115 amu. We report details of the first muon spin rotation (μSR) measurements of the chemical reaction rate constant of (4)Heμ with molecular hydrogen, (4)Heμ + H(2) → (4)HeμH + H, at temperatures of 295.5, 405, and 500 K, as well as a μSR measurement of the hyperfine coupling constant of muonic He at high pressures. The experimental rate constants, k(Heμ), are compared with the predictions of accurate quantum mechanical (QM) dynamics calculations carried out on a well converged Born-Huang (BH) potential energy surface, based on complete configuration interaction calculations and including a Born-Oppenheimer diagonal correction. At the two highest measured temperatures the agreement between the quantum theory and experiment is good to excellent, well within experimental uncertainties that include an estimate of possible systematic error, but at 295.5 K the quantum calculations for k(Heμ) are below the experimental value by 2.1 times the experimental uncertainty estimates. Possible reasons for this discrepancy are discussed. Variational transition state theory calculations with multidimensional tunneling have also been carried out for k(Heμ) on the BH surface, and they agree with the accurate QM rate constants to within 30% over a wider temperature range of 200-1000 K. Comparisons between theory and experiment are also presented for the rate constants for both the D + H(2) and Mu + H(2) reactions in a novel study of kinetic isotope effects for the H + H(2) reactions over a factor of 36.1 in isotopic mass of the atomic reactant. © 2011 American Institute of Physics

  17. Factors affecting the thermal environment of Agassiz’s Desert Tortoise (Gopherus agassizii) cover sites in the Central Mojave Desert during periods of temperature extremes

    Science.gov (United States)

    Mack, Jeremy S.; Berry, Kristin H.; Miller, David; Carlson, Andrea S.

    2015-01-01

    Agassiz's Desert Tortoises (Gopherus agassizii) spend >95% of their lives underground in cover sites that serve as thermal buffers from temperatures, which can fluctuate >40°C on a daily and seasonal basis. We monitored temperatures at 30 active tortoise cover sites within the Soda Mountains, San Bernardino County, California, from February 2004 to September 2006. Cover sites varied in type and structural characteristics, including opening height and width, soil cover depth over the opening, aspect, tunnel length, and surficial geology. We focused our analyses on periods of extreme temperature: in summer, between July 1 and September 1, and winter, between November 1 and February 15. With the use of multivariate regression tree analyses, we found cover-site temperatures were influenced largely by tunnel length and subsequently opening width and soil cover. Linear regression models further showed that increasing tunnel length increased temperature stability and dampened seasonal temperature extremes. Climate change models predict increased warming for southwestern North America. Cover sites that buffer temperature extremes and fluctuations will become increasingly important for survival of tortoises. In planning future translocation projects and conservation efforts, decision makers should consider habitats with terrain and underlying substrate that sustain cover sites with long tunnels and expanded openings for tortoises living under temperature extremes similar to those described here or as projected in the future.

  18. Empowering a mesophilic inoculum for thermophilic nitrification: Growth mode and temperature pattern as critical proliferation factors for archaeal ammonia oxidizers.

    Science.gov (United States)

    Courtens, Emilie N P; Vandekerckhove, Tom; Prat, Delphine; Vilchez-Vargas, Ramiro; Vital, Marius; Pieper, Dietmar H; Meerbergen, Ken; Lievens, Bart; Boon, Nico; Vlaeminck, Siegfried E

    2016-04-01

    Cost-efficient biological treatment of warm nitrogenous wastewaters requires the development of thermophilic nitrogen removal processes. Only one thermophilic nitrifying bioreactor was described so far, achieving 200 mg N L(-1) d(-1) after more than 300 days of enrichment from compost samples. From the practical point of view in which existing plants would be upgraded, however, a more time-efficient development strategy based on mesophilic nitrifying sludge is preferred. This study evaluated the adaptive capacities of mesophilic nitrifying sludge for two linear temperature increase patterns (non-oscillating vs. oscillating), two different slopes (0.25 vs. 0.08 °C d(-1)) and two different reactor types (floc vs. biofilm growth). The oscillating temperature pattern (0.25 °C d(-1)) and the moving bed biofilm reactor (0.08 °C d(-1)) could not reach nitrification at temperatures higher than 46 °C. However, nitrification rates up to 800 mg N L(-1) d(-1) and 150 mg N g(-1) volatile suspended solids d(-1) were achieved at a temperature as high as 49 °C by imposing the slowest linear temperature increase to floccular sludge. Microbial community analysis revealed that this successful transition was related with a shift in ammonium oxidizing archaea dominating ammonia oxidizing bacteria, while for nitrite oxidation Nitrospira spp. was constantly more abundant than Nitrobacter spp.. This observation was accompanied with an increase in observed sludge yield and a shift in maximal optimum temperature, determined with ex-situ temperature sensitivity measurements, predicting an upcoming reactor failure at higher temperature. Overall, this study achieved nitrification at 49 °C within 150 days by gradual adaptation of mesophilic sludge, and showed that ex-situ temperature sensitivity screening can be used to monitor and steer the transition process.

  19. Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.

    Science.gov (United States)

    Nuss, Jonathan E; Kehn-Hall, Kylene; Benedict, Ashwini; Costantino, Julie; Ward, Michael; Peyser, Brian D; Retterer, Cary J; Tressler, Lyal E; Wanner, Laura M; McGovern, Hugh F; Zaidi, Anum; Anthony, Scott M; Kota, Krishna P; Bavari, Sina; Hakami, Ramin M

    2014-01-01

    Rift Valley fever is a potentially fatal disease of humans and domestic animals caused by Rift Valley fever virus (RVFV). Infection with RVFV in ruminants can cause near 100% abortion rates and recent outbreaks in naïve human populations have suggested case fatality rates of greater than thirty percent. To elucidate the roles that host proteins play during RVFV infection, proteomic analysis of RVFV virions was conducted using complementary analytical approaches, followed by functional validation studies of select identified host factors. Coupling the more traditional Gel LC/MS/MS approach (SDS PAGE followed by liquid chromatography tandem mass spectrometry) with an alternative technique that preserves protein complexes allowed the protein complement of these viral particles to be thoroughly examined. In addition to viral proteins present within the virions and virion-associated host proteins, multiple macromolecular complexes were identified. Bioinformatic analysis showed that host chaperones were among over-represented protein families associated with virions, and functional experiments using siRNA gene silencing and small molecule inhibitors identified several of these heat shock proteins, including heat shock protein 90 (HSP90), as important viral host factors. Further analysis indicated that HSP inhibition effects occur during the replication/transcription phase of the virus life cycle, leading to significant lowering of viral titers without compromising the functional capacity of released virions. Overall, these studies provide much needed further insight into interactions between RVFV and host cells, increasing our understanding of the infection process and suggesting novel strategies for anti-viral development. In particular, considering that several HSP90 inhibitors have been advancing through clinical trials for cancer treatment, these results also highlight the exciting potential of repurposing HSP90 inhibitors to treat RVF.

  20. Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.

    Directory of Open Access Journals (Sweden)

    Jonathan E Nuss

    Full Text Available Rift Valley fever is a potentially fatal disease of humans and domestic animals caused by Rift Valley fever virus (RVFV. Infection with RVFV in ruminants can cause near 100% abortion rates and recent outbreaks in naïve human populations have suggested case fatality rates of greater than thirty percent. To elucidate the roles that host proteins play during RVFV infection, proteomic analysis of RVFV virions was conducted using complementary analytical approaches, followed by functional validation studies of select identified host factors. Coupling the more traditional Gel LC/MS/MS approach (SDS PAGE followed by liquid chromatography tandem mass spectrometry with an alternative technique that preserves protein complexes allowed the protein complement of these viral particles to be thoroughly examined. In addition to viral proteins present within the virions and virion-associated host proteins, multiple macromolecular complexes were identified. Bioinformatic analysis showed that host chaperones were among over-represented protein families associated with virions, and functional experiments using siRNA gene silencing and small molecule inhibitors identified several of these heat shock proteins, including heat shock protein 90 (HSP90, as important viral host factors. Further analysis indicated that HSP inhibition effects occur during the replication/transcription phase of the virus life cycle, leading to significant lowering of viral titers without compromising the functional capacity of released virions. Overall, these studies provide much needed further insight into interactions between RVFV and host cells, increasing our understanding of the infection process and suggesting novel strategies for anti-viral development. In particular, considering that several HSP90 inhibitors have been advancing through clinical trials for cancer treatment, these results also highlight the exciting potential of repurposing HSP90 inhibitors to treat RVF.

  1. Physical mechanism or evolutionary trade-off? Factors dictating the relationship between metabolic rate and ambient temperature in carabid beetles.

    Science.gov (United States)

    Gudowska, Agnieszka; Schramm, Bartosz W; Czarnoleski, Marcin; Kozłowski, Jan; Bauchinger, Ulf

    2017-08-01

    The tight association between ambient temperature (T) and metabolic rate (MR) is a common occurrence in ectotherms, but the determinants of this association are not fully understood. This study examined whether the relationship between MR and T is the same among individuals, as predicted by the Universal Temperature Dependence hypothesis, or whether this relationship differs between them. We used flow-through respirometry to measure standard MR and to determine gas exchange patterns for 111 individuals of three Carabidae species which differ in size (Abax ovalis, Carabus linnei and C. coriaceus), exposed to four different temperatures (ten individuals of each species measured at 6, 11, 16 and 21°C). We found a significant interaction between ln body mass and the inverse of temperature, indicating that in a given species, the effect of temperature on MR was weaker in larger individuals than in smaller individuals. Overall, this finding shows that the thermal dependence of MR is not body mass invariant. We observed three types of gas exchange patterns among beetles: discontinuous, cyclic and continuous. Additionally, the appearance of these patterns was associated with MR and T. Evolution in diverse terrestrial environments could affect diverse ventilation patterns, which accommodate changes in metabolism in response to temperature variation. In conclusion, explaining the variance in metabolism only through fundamental physical laws of thermodynamics, as predicted by the Universal Temperature Dependence hypothesis, appears to oversimplify the complexity of nature, ignoring evolutionary trade-offs that should be taken into account in the temperature - metabolism relationship. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Measurement and Calculation of Electrochemical Potentials in Hydrogenated High Temperature Water, including an Evaluation of the Yttria-Stabilized Zirconia/Iron-Iron Oxide (Fe/Fe3O4) Probe as Reference Electrode

    Energy Technology Data Exchange (ETDEWEB)

    Steven A. Attanasio; David S. Morton; Mark A. Ando

    2001-10-22

    The importance of knowing the electrochemical corrosion potential (ECP, also referred to as E{sub con}) of nickel-base alloys in hydrogenated water is related to the need to understand the effects of dissolved (i.e., aqueous) hydrogen concentration ([H{sub 2}]) on primary water stress corrosion cracking (PWSCC). Also, the use of a reference electrode (RE) can improve test quality by heightening the ability to detect instances of out-of-specification or unexpected chemistry. Three methods are used to measure and calculate the ECP of nickel-based alloys in hydrogenated water containing {approx} 1 to 150 scc/kg H{sub 2} (0.1 to 13.6 ppm H{sub 2}) at 260 to 360 C. The three methods are referred to as the specimen/component method, the platinum (Pt) method, and the yttria-stabilized zirconia/iron-iron oxide (YSZ/Fe-Fe{sub 3}O{sub 4}) RE method. The specimen/component method relies upon the assumption that the specimen or component behaves as a hydrogen electrode, and its E{sub corr} is calculated using the Nernst equation. The present work shows that this method is valid for aqueous H{sub 2} levels {ge} {approx} 5 to 10 scc/kg H{sub 2}. The Pt method uses a voltage measurement between the specimen or component and a Pt electrode, with the Pt assumed to behave as a hydrogen electrode; this method is valid as long as the aqueous H{sub 2}level is known. The YSZ/Fe-Fe{sub 3}O{sub 4}, which represents a relatively new approach for measuring E{sub corr} in this environment, can be used even if the aqueous H{sub 2} level is unknown. The electrochemical performance of the YSZ/Fe-Fe{sub 3}O{sub 4} probe supports its viability as a RE for use in high temperature hydrogenated water. Recent design modifications incorporating a teflon sealant have improved the durability of this RE (however, some of the REs do still fail prematurely due to water in-leakage). The Pt method is judged to represent the best overall approach, though there are cases where the other methods are superior

  3. Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation.

    Science.gov (United States)

    Carruthers, Nicholas J; Stemmer, Paul M; Chen, Ben; Valeriote, Frederick; Gao, Xiaohua; Guatam, Subhash C; Shaw, Jiajiu

    2017-09-15

    UTL-5g is a novel small-molecule TNF-alpha modulator. It reduces cisplatin-induced side effects by protecting kidney, liver, and platelets, thereby increasing tolerance for cisplatin. UTL-5g also reduces radiation-induced acute liver toxicity. The mechanism of action for UTL-5g is not clear at the present time. A phosphoproteomic analysis to a depth of 4943 phosphopeptides and a luminescence-based transcription factor activity assay were used to provide complementary analyses of signaling events that were disrupted by UTL-5g in RAW 264.7 cells. Transcriptional activity downstream of the interferon gamma, IL-6, type 1 Interferon, TGF-β, PKC/Ca(2+) and the glucocorticoid receptor pathways were disrupted by UTL-5g. Phosphoproteomic analysis indicated that hyperphosphorylation of proteins involved in actin remodeling was suppressed by UTL-5g (gene set analysis, FDR 5g. This global characterization of UTL-5g activity in a macrophage cell line discovered that it disrupts selected aspects of LPS signaling including Stat3 activation and actin remodeling providing new insight on how UTL-5g acts to reduce cisplatin-induced side effects. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. The rice R2R3-MYB transcription factor OsMYB55 is involved in the tolerance to high temperature and modulates amino acid metabolism.

    Directory of Open Access Journals (Sweden)

    Ashraf El-Kereamy

    Full Text Available Temperatures higher than the optimum negatively affects plant growth and development. Tolerance to high temperature is a complex process that involves several pathways. Understanding this process, especially in crops such as rice, is essential to prepare for predicted climate changes due to global warming. Here, we show that OsMYB55 is induced by high temperature and overexpression of OsMYB55 resulted in improved plant growth under high temperature and decreased the negative effect of high temperature on grain yield. Transcriptome analysis revealed an increase in expression of several genes involved in amino acids metabolism. We demonstrate that OsMYB55 binds to the promoter regions of target genes and directly activates expression of some of those genes including glutamine synthetase (OsGS1;2 glutamine amidotransferase (GAT1 and glutamate decarboxylase 3 (GAD3. OsMYB55 overexpression resulted in an increase in total amino acid content and of the individual amino acids produced by the activation of the above mentioned genes and known for their roles in stress tolerance, namely L-glutamic acid, GABA and arginine especially under high temperature condition. In conclusion, overexpression of OsMYB55 improves rice plant tolerance to high temperature, and this high tolerance is associated with enhanced amino acid metabolism through transcription activation.

  5. Using the physical decomposition method to study the effects of Arctic factors on wintertime temperatures in the Northern Hemisphere and China

    Institute of Scientific and Technical Information of China (English)

    SUI Cuijuan; ZHANG Zhanhai; CAI Yi; WU Huiding

    2014-01-01

    The physical decomposition method separates atmospheric variables into four parts, correlating each with solar radiation, land–sea distribution, and inter-annual and seasonal internal forcing, strengthening the anomaly signal and increasing the correlation between variables. This method was applied to the reanalysis data from the National Centers for Environmental Prediction/National Center for Atmospheric Research (NCEP/NCAR), to study the effects of Arctic factors (Arctic oscillation (AO) and Arctic polar vortex) on wintertime temperatures in the Northern Hemisphere and China. It was found that AO effects on zonal average temperature disturbance could persist for 1 month. In the AO negative phase in wintertime, the temperatures are lower in the mid–high latitudes than in normal years, but higher in low latitudes. When the polar vortex area is bigger, the zonal average temperature is lower at 50°N. Inlfuenced mainly by meridional circulation enhancement, cold air lfows from high to low latitudes;thus, the temperatures in Continental Europe and the North American continent exhibit an antiphase seesaw relationship. When the AO is in negative phase and the Arctic polar vortex larger, the temperature is lower in Siberia, but higher in Greenland and the Bering Strait. Inlfuenced by westerly troughs and ridges, the polar air disperses mainly along the tracks of atmospheric activity centers. The AO index can be considered a predictor of wintertime temperature in China. When the AO is in negative phase or the Asian polar vortex is intensiifed, temperatures in Northeast China and Inner Mongolia are lower, because under the inlfuence of the Siberia High and northeast cold vortex, the cold air lfows southwards.

  6. Temperature dependence of band gap ratio and Q-factor defect mode in a semiconductor quaternary alloy hexagonal photonic-crystal hole slab

    Science.gov (United States)

    Sánchez-Cano, R.; Porras-Montenegro, N.

    2016-04-01

    We present numerical predictions for the photonic TE-like band gap ratio and the quality factors of symmetric localized defect as a function of the thickness slab and temperature by the use of plane wave expansion and the finite-difference time-domain methods. The photonic-crystal hole slab is composed of a 2D hexagonal array with identical air holes and a circular cross section, embedded in a non-dispersive III-V semiconductor quaternary alloy slab, which has a high value of dielectric function in the near-infrared region, and the symmetric defect is formed by increasing the radius of a single hole in the 2D hexagonal lattice. We show that the band gap ratio depends linearly on the temperature in the range 150-400 K. Our results show a strong temperature dependence of the quality factor Q, the maximum (Q = 7000) is reached at T = 350 hbox {K}, but if the temperature continues to increase, the efficiency drops sharply. Furthermore, we present numerical predictions for the electromagnetic field distribution at T = 350 hbox {K}.

  7. Brain temperature and exercise performance

    DEFF Research Database (Denmark)

    Nybo, Lars

    2012-01-01

    will impair voluntary motor activation during sustained maximal contractions. In humans the brain temperature increases in parallel with that of the body core making it very difficult to evaluate the independent effect of the cerebral temperature. Experiments with separate manipulation of the brain...... temperature in exercising goats indicate that excessive brain hyperthermia will directly affect motor performance. However, several homeostatic changes arise in parallel with hyperthermia including factors that may influence both peripheral and central fatigue and it is likely that these changes interact...... with the inhibitory effect of an elevated brain temperature....

  8. International Normalized Ratio (INR), coagulation factor activities and calibrated automated thrombin generation - influence of 24 h storage at ambient temperature

    DEFF Research Database (Denmark)

    Christensen, T D; Jensen, C; Larsen, T B

    2010-01-01

    International Normalized Ratio (INR) measurements are used to monitor oral anticoagulation therapy with coumarins. Single coagulation factor activities and calibrated automated thrombin (CAT) generation are considered as more advanced methods for evaluating overall haemostatic capacity. The aims...

  9. Correlation Feature Selection and Mutual Information Theory Based Quantitative Research on Meteorological Impact Factors of Module Temperature for Solar Photovoltaic Systems

    Directory of Open Access Journals (Sweden)

    Yujing Sun

    2016-12-01

    Full Text Available The module temperature is the most important parameter influencing the output power of solar photovoltaic (PV systems, aside from solar irradiance. In this paper, we focus on the interdisciplinary research that combines the correlation analysis, mutual information (MI and heat transfer theory, which aims to figure out the correlative relations between different meteorological impact factors (MIFs and PV module temperature from both quality and quantitative aspects. The identification and confirmation of primary MIFs of PV module temperature are investigated as the first step of this research from the perspective of physical meaning and mathematical analysis about electrical performance and thermal characteristic of PV modules based on PV effect and heat transfer theory. Furthermore, the quantitative description of the MIFs influence on PV module temperature is mathematically formulated as several indexes using correlation-based feature selection (CFS and MI theory to explore the specific impact degrees under four different typical weather statuses named general weather classes (GWCs. Case studies for the proposed methods were conducted using actual measurement data of a 500 kW grid-connected solar PV plant in China. The results not only verified the knowledge about the main MIFs of PV module temperatures, more importantly, but also provide the specific ratio of quantitative impact degrees of these three MIFs respectively through CFS and MI based measures under four different GWCs.

  10. Alternate stresses and temperature variation as factors of influence of ultrasonic vibration on mechanical and functional properties of shape memory alloys.

    Science.gov (United States)

    Belyaev, Sergey; Volkov, Alexander; Resnina, Natalia

    2014-01-01

    It is known that the main factors in a variation in the shape memory alloy properties under insonation are heating of the material and alternate stresses action. In the present work the experimental study of the mechanical behaviour and functional properties of shape memory alloy under the action of alternate stresses and varying temperature was carried out. The data obtained had demonstrated that an increase in temperature of the sample resulted in a decrease or increase in deformation stress depending on the structural state of the TiNi sample. It was shown that in the case of the alloy in the martensitic state, a decrease in stress was observed, and on the other hand, in the austenitic state an increase in stress took place. It was found that action of alternate stresses led to appearance of strain jumps on the strain-temperature curves during cooling and heating the sample through the temperature range of martensitic transformation under the constant stress. The value of the strain jumps depended on the amplitude of alternate stresses and the completeness of martensitic transformation. It was shown that the heat action of ultrasonic vibration to the mechanical behaviour of shape memory alloys was due to the non-monotonic dependence of yield stress on the temperature. The force action of ultrasonic vibration to the functional properties was caused by formation of additional oriented martensite. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. On the effect of temperature on the threshold stress intensity factor of delayed hydride cracking in light water reactor fuel cladding

    Energy Technology Data Exchange (ETDEWEB)

    Holston, Anna-MariaAlvarez; Stjarnsater, Johan [Studsvik Nuclear AB, Nykoping (Sweden)

    2017-06-15

    Delayed hydride cracking (DHC) was first observed in pressure tubes in Canadian CANDU reactors. In light water reactors, DHC was not observed until the late 1990s in high-burnup boiling water reactor (BWR) fuel cladding. In recent years, the focus on DHC has resurfaced in light of the increased interest in the cladding integrity during interim conditions. In principle, all spent fuel in the wet pools has sufficient hydrogen content for DHC to operate below 300°C. It is therefore of importance to establish the critical parameters for DHC to operate. This work studies the threshold stress intensity factor (K{sub IH}) to initiate DHC as a function of temperature in Zry-4 for temperatures between 227°C and 315°C. The experimental technique used in this study was the pin-loading testing technique. To determine the K{sub IH}, an unloading method was used where the load was successively reduced in a stepwise manner until no cracking was observed during 24 hours. The results showed that there was moderate temperature behavior at lower temperatures. Around 300°C, there was a sharp increase in K{sub IH} indicating the upper temperature limit for DHC. The value for K{sub IH} at 227°C was determined to be 2.6 ± 0.3 MPa √m.

  12. Investigation of the Dominant Factors Influencing the ERA15 Temperature Increments at the Subtropical and Temperate Belts with a Focus over the Eastern Mediterranean Region

    Directory of Open Access Journals (Sweden)

    Tali Hirsch-Eshkol

    2014-08-01

    Full Text Available A stepwise multi regression-based statistics was employed for prioritizing the influence of several factors, anthropogenic and/or natural, on the ERA15 temperature increments. The 5 factors that are defined as predictors are: topography, aerosol index (TOMS-AI, tropospheric vertical velocity along with two anthropogenic factors, population density and land use changes (Land Use Change Index (LUCI and Normalized Difference Vegetation Index (NDVI trends. The seismic hazard assessment factor was also chosen as the “dummy variable” for validity. Special focus was given to the land use change factor, which was based on two different data sets; Human Impacts on Terrestrial Ecosystems (HITE data of historical land use/land cover data and of NDVI trends during 1982 and 1991. The increment analysis updates of temperature, increments analysis update (IAU (T, the predicted variable, was obtained from the ERA15 (1979–1993 reanalysis. The research consists of both spatial and vertical analyses, as well as the potential synergies of selected variables. The spatial geographic analysis is divided into three categories; (1 coarse region; (2 subregion analysis; and (c a “small cell” of 4° × 4° analysis covering the global domain. It is shown that the following three factors, topography, TOMS-AI and NDVI, are statistically significant (at the p < 0.05 level in the relationship with the IAU (T, which means that they are the most effective predictors of IAU (T, especially at the 700-hPa level during March–June. The 850-hPa level presents the weakest contribution to IAU (T, probably due to the contradicting influences of the various variables at this level. It was found that the land use effect, as expressed by the NDVI trends factor, shows a strong decrease with height and is one of the most influential near-surface factors over the East Mediterranean (EM, which explains up to 20% of the temperature increments in January at 700 hPa. Moreover

  13. Static and Dynamic Structure Factors with Account of the Ion Structure for High-temperature Alkali and Alkaline Earth Plasmas

    CERN Document Server

    Sadykova, S P; Tkachenko, I M

    2010-01-01

    The $e-e$, $e-i$, $i-i$ and charge-charge static structure factors are calculated for alkali and Be$^{2+}$ plasmas using the method described by Gregori et al. in \\cite{bibGreg2006}. The dynamic structure factors for alkali plasmas are calculated using the method of moments \\cite{bibAdam83}, \\cite{bibAdam93}. In both methods the screened Hellmann-Gurskii-Krasko potential, obtained on the basis of Bogolyubov's method, has been used taking into account not only the quantum-mechanical effects but also the ion structure \\cite{bib73}. PACS: 52.27.Aj (Alkali and alkaline earth plasmas, Static and dynamic structure factors), 52.25.Kn (Thermodynamics of plasmas), 52.38.Ph (X-ray scattering)

  14. Investigation of some factors affecting the sensory level of spinal anesthesia: position, baricity, temperature, needle direction and speed of injection

    NARCIS (Netherlands)

    R. Stienstra

    1990-01-01

    textabstractThe purpose of the studies to be presented was to investigate different factors influencing spinal anesthesia with bupivacaine 0.5 %. More specifically, the first study investigated the differences in intrathecal distribution as measured by the maximum sensory level of blockade between t

  15. Investigation of some factors affecting the sensory level of spinal anesthesia: position, baricity, temperature, needle direction and speed of injection

    NARCIS (Netherlands)

    R. Stienstra

    1990-01-01

    textabstractThe purpose of the studies to be presented was to investigate different factors influencing spinal anesthesia with bupivacaine 0.5 %. More specifically, the first study investigated the differences in intrathecal distribution as measured by the maximum sensory level of blockade

  16. Temperature-dependent determination of electron heat capacity and electron-phonon coupling factor for Fe0.72Cr0.18Ni0.1

    Science.gov (United States)

    Winter, Jan; Sotrop, Jürgen; Borek, Stephan; Huber, Heinz P.; Minár, Jan

    2016-04-01

    A theoretical approach using ab initio calculations was applied to study the interaction of an ultrashort laser pulse with the metal alloy Fe0.72Cr0.18Ni0.1 (AISI 304). The electronic structure was simulated by taking into account the chemical and magnetic disorder of the alloy by the coherent potential approximation implemented in a fully relativistic Korringa-Kohn-Rostoker formalism in the framework of spin density functional theory. A self-consistent calculation of the electronic structure using the Matsubara technique in the paramagnetic state of Fe0.72Cr0.18Ni0.1 for finite temperatures was applied. Utilizing these predictions we determined the electron heat capacity and the electron-phonon coupling factor of Fe0.72Cr0.18Ni0.1 in dependence on the electron temperature for two-temperature model applications. Compared with pure Fe a maximum deviation of 5% for the electron heat capacity and 25% for the electron-phonon coupling factor was found.

  17. Genetic Variation for Thermotolerance in Lettuce Seed Germination Is Associated with Temperature-Sensitive Regulation of ETHYLENE RESPONSE FACTOR1 (ERF1)1[OPEN

    Science.gov (United States)

    O’Brien, Laurel K.; Truco, Maria Jose; Huo, Heqiang; Sideman, Rebecca; Hayes, Ryan; Michelmore, Richard W.

    2016-01-01

    Seeds of most lettuce (Lactuca sativa) cultivars are susceptible to thermoinhibition, or failure to germinate at temperatures above approximately 28°C, creating problems for crop establishment in the field. Identifying genes controlling thermoinhibition would enable the development of cultivars lacking this trait and, therefore, being less sensitive to high temperatures during planting. Seeds of a primitive accession (PI251246) of lettuce exhibited high-temperature germination capacity up to 33°C. Screening a recombinant inbred line population developed from PI215246 and cv Salinas identified a major quantitative trait locus (Htg9.1) from PI251246 associated with the high-temperature germination phenotype. Further genetic analyses discovered a tight linkage of the Htg9.1 phenotype with a specific DNA marker (NM4182) located on a single genomic sequence scaffold. Expression analyses of the 44 genes encoded in this genomic region revealed that only a homolog of Arabidopsis (Arabidopsis thaliana) ETHYLENE RESPONSE FACTOR1 (termed LsERF1) was differentially expressed between PI251246 and cv Salinas seeds imbibed at high temperature (30°C). LsERF1 belongs to a large family of transcription factors associated with the ethylene-signaling pathway. Physiological assays of ethylene synthesis, response, and action in parental and near-isogenic Htg9.1 genotypes strongly implicate LsERF1 as the gene responsible for the Htg9.1 phenotype, consistent with the established role for ethylene in germination thermotolerance of Compositae seeds. Expression analyses of genes associated with the abscisic acid and gibberellin biosynthetic pathways and results of biosynthetic inhibitor and hormone response experiments also support the hypothesis that differential regulation of LsERF1 expression in PI251246 seeds elevates their upper temperature limit for germination through interactions among pathways regulated by these hormones. Our results support a model in which LsERF1 acts through

  18. Genetic Variation for Thermotolerance in Lettuce Seed Germination Is Associated with Temperature-Sensitive Regulation of ETHYLENE RESPONSE FACTOR1 (ERF1).

    Science.gov (United States)

    Yoong, Fei-Yian; O'Brien, Laurel K; Truco, Maria Jose; Huo, Heqiang; Sideman, Rebecca; Hayes, Ryan; Michelmore, Richard W; Bradford, Kent J

    2016-01-01

    Seeds of most lettuce (Lactuca sativa) cultivars are susceptible to thermoinhibition, or failure to germinate at temperatures above approximately 28°C, creating problems for crop establishment in the field. Identifying genes controlling thermoinhibition would enable the development of cultivars lacking this trait and, therefore, being less sensitive to high temperatures during planting. Seeds of a primitive accession (PI251246) of lettuce exhibited high-temperature germination capacity up to 33°C. Screening a recombinant inbred line population developed from PI215246 and cv Salinas identified a major quantitative trait locus (Htg9.1) from PI251246 associated with the high-temperature germination phenotype. Further genetic analyses discovered a tight linkage of the Htg9.1 phenotype with a specific DNA marker (NM4182) located on a single genomic sequence scaffold. Expression analyses of the 44 genes encoded in this genomic region revealed that only a homolog of Arabidopsis (Arabidopsis thaliana) ETHYLENE RESPONSE FACTOR1 (termed LsERF1) was differentially expressed between PI251246 and cv Salinas seeds imbibed at high temperature (30°C). LsERF1 belongs to a large family of transcription factors associated with the ethylene-signaling pathway. Physiological assays of ethylene synthesis, response, and action in parental and near-isogenic Htg9.1 genotypes strongly implicate LsERF1 as the gene responsible for the Htg9.1 phenotype, consistent with the established role for ethylene in germination thermotolerance of Compositae seeds. Expression analyses of genes associated with the abscisic acid and gibberellin biosynthetic pathways and results of biosynthetic inhibitor and hormone response experiments also support the hypothesis that differential regulation of LsERF1 expression in PI251246 seeds elevates their upper temperature limit for germination through interactions among pathways regulated by these hormones. Our results support a model in which LsERF1 acts through

  19. Evaluation of limiting factors affecting photovoltaic performance of low-temperature-processed TiO₂ films in dye-sensitized solar cells.

    Science.gov (United States)

    Lee, Taek-Yong; Kim, Hui-Seon; Park, Nam-Gyu

    2014-04-14

    Limiting factors affecting photovoltaic performance of dye-sensitized solar cell employing low-temperature-processed TiO2 films were investigated. TiO2 films were prepared at a low temperature of 200 °C using the normal alcohol-containing binder-free TiO2 paste (LT200). Their photovoltaic performance was compared to a high-temperature (550 °C) annealed TiO2 film prepared using a polymer binder containing TiO2 paste (HT550). Compared to the proportional increase in conversion efficiency with TiO2 film thickness upto 14 μm for HT550, the increase in efficiency was terminated at relatively smaller thickness of about 8 μm for LT200 mainly due to unaugmented photocurrent. From the transient photocurrent-voltage studies, the electron transport rate was found to be almost identical, while charge recombination was one order of magnitude faster for LT200. Consequently, the electron diffusion length was more than 2-3 times shorter for LT200 than for HT550. Electron diffusion length and electron life time obtained from electrochemical impedance analysis were well consistent with those observed from transient measurement. Density of states (DOS) was evaluated to be shallow and narrow in LT200, which was responsible for limiting photovoltaic performance in the low-temperature processed TiO2 film.

  20. Neutralization of radical toxicity by temperature-dependent modulation of extracellular SOD activity in coral bleaching pathogen Vibrio shiloi and its role as a virulence factor.

    Science.gov (United States)

    Murali, Malliga Raman; Raja, Subramaniya Bharathi; Devaraj, Sivasitambaram Niranjali

    2010-08-01

    Vibrio shiloi is the first and well-documented bacterium which causes coral bleaching, particularly, during summer, when seawater temperature is between 26 and 31 degrees C. Coral bleaching is the disruption of the symbiotic association between coral hosts and their photosynthetic microalgae zooxanthellae. This is either due to lowered resistance in corals to infection or increased virulence of the bacterium at the higher sea surface temperature. The concentration of the oxygen and resulting oxygen radicals produced by the zooxanthellae during photosynthesis are highly toxic to bacteria, which also assist corals in resisting the infection. Hence, in this study we examined the effect of different temperatures on the activity of a novel extracellular SOD in V. shiloi. We also partially characterized the SOD and clearly confirmed that the extracellular SOD produced by V. shiloi is Mn-SOD type, as it was not inhibited by H2O2 or KCN. Performing chemical susceptibility killing assay, we confirmed that extracellular SOD may act as first line of defense for the bacteria against the reactive oxygen species. Since, increased activity of novel Mn-SOD at higher temperature, leads to the neutralization of radical toxicity and facilitates the survival of V. shiloi. Hence, the extracellular Mn-SOD may be considered as a virulence factor.

  1. Long-term high-temperature and pH stability assessment of modern commercially available stationary phases by using retention factor analysis.

    Science.gov (United States)

    Haun, Jakob; Oeste, Katja; Teutenberg, Thorsten; Schmidt, Torsten C

    2012-11-09

    High-temperature liquid chromatography provides several advantages concerning HPLC method development and is needed to realize special hyphenation techniques. However, hardware limitations and stationary phase degradation can prevent the successful application of this technique. Therefore, column stability is of major importance. The presented study contains results of long-term high-temperature stability tests for eight modern commercially available HPLC stationary phases. Six of them were silica-based reversed-phase C18 columns tested according to an earlier reported procedure (Teutenberg, 2009 [12]). On the basis of the extended data set that covers a wide range of column technologies, a comparative approach using retention factor analysis was evaluated in order to categorize the columns according to their long-term high-temperature stability at 150 °C and changing pH value. This approach offers a more objective alternative to conventional listings in which temperature maxima are compared for columns tested under different conditions. Additionally, customized tests are presented for one promising polymer-based C18 stationary phase and an amide column for hydrophilic interaction liquid chromatography.

  2. To investigate the mechanism about the pathogenic factors including Hhcy, in coronary artery coronary endothelial cell damage mechanism%Hhcy对冠脉内皮细胞损伤机制的临床研究

    Institute of Scientific and Technical Information of China (English)

    张庆成; 张向峰; 韩晓丹

    2016-01-01

    Objective To investigate the mechanism about the pathogenic factors including Hhcy, etc in coronary artery coronary endothelial cell damage mechanism.Methods In this paper, according to coronary angiography examination,select 121 cases of coronary heart disease (CHD) patients. According to the clinical symptom of coronary heart disease group, heartache group 71 cases, acute myocardial infarction group 50 cases. 95 cases of normal healthy subjects were selected as control group. The Hcy, EC, ET, niacin and vitamin B12 were measured.Results In patients with coronary artery stenosis groups of Hcy, EC, ET, niacin, vitamin B12 indicators along with the change of coronary artery stenosis degree change, the more the degree of stenosis serious Hcy, EC, ET, etc indicators increased, the more obvious, in severe stenosis group (P<0.01). Hcy, EC, ET in CHD group significantly increased than the normal control group. The study also found that the level of serum Hcy and EC, Hcy and ET, Hcy and niacin had a positive correlation (r=0.61, r=0.55, r=0.62). Hcy had niacin, Hcy had vitamin B12 had a negative correlation (r=-0.62, r=-0.58).Conclusions The level of Hcy, EC, ET increasing and the level of niacin, vitamin B12 reducing has important significance in coronary artery intimal injury, plaque formation, leading to coronary artery stenosis.%目的:探讨Hhcy等致病因素在冠脉冠脉内皮细胞损伤的机制。方法:本文选择冠心病(CHD)患者121例,根据冠心病临床症状分组,心痛组71例,急性心肌梗塞组50例,选取95例冠状动脉造影等检查为正常健康者作为正常对照组。测定所有受试者同型半胱氨酸(Hcy),内皮细胞(EC),内皮素(ET),烟酸,维生素B12等指标。结果:冠脉狭窄患者各组Hcy,EC,ET、烟酸,维生素B12等指标随冠脉狭窄程度的改变而改变,狭窄程度愈严重Hcy,EC,ET等指标增高越明显(P<0.01)。CHD组Hcy,EC,ET等指标较正

  3. A putative functional MYB transcription factor induced by low temperature regulates anthocyanin biosynthesis in purple kale (Brassica Oleracea var. acephala f. tricolor).

    Science.gov (United States)

    Zhang, Bin; Hu, Zongli; Zhang, Yanjie; Li, Yali; Zhou, Shuang; Chen, Guoping

    2012-02-01

    The purple kale (Brassica Oleracea var. acephala f. tricolor) is a mutation in kales, giving the mutant phenotype of brilliant purple color in the interior. Total anthocyanin analysis showed that the amount of anthocyanins in the purple kale was up to 1.73 mg g(-1) while no anthocyanin was detected in the white kale. To elucidate the molecular mechanism of the anthocyanin biosynthesis in the purple kale, we analyzed the expression of structural genes and some transcription factors associated with anthocyanin biosynthesis in the purple cultivar "Red Dove" and the white cultivar "White Dove". The result showed that nearly all the anthocyanin biosynthetic genes showed higher expression levels in the purple cultivar than in the white cultivar, especially for DFR and ANS, they were barely detected in the white cultivar. Interestingly, the fact that a R2R3 MYB transcription factor named BoPAP1 was extremely up-regulated in the purple kale and induced by low temperature attracted our attention. Further sequence analysis showed that BoPAP1 shared high similarity with AtPAP1 and BoMYB1. In addition, the anthocyanin accumulation in the purple kale is strongly induced by the low temperature stress. The total anthocyanin contents in the purple kale under low temperature were about 50-fold higher than the plants grown in the greenhouse. The expression of anthocyanin biosynthetic genes C4H, F3H, DFR, ANS and UFGT were all enhanced under the low temperature. These evidences strongly suggest that BoPAP1 may play an important role in activating the anthocyanin structural genes for the abundant anthocyanin accumulation in the purple kale.

  4. To flower or not to flower, a temperature-sensitive decision. Characterization of flowering responses at high ambient temperature in Arabidopsis thaliana

    NARCIS (Netherlands)

    Rodenburg, N.

    2015-01-01

    To maximize fitness, plants use environmental cues to optimize growth processes. One of the processes under strong environmental regulation is flowering. Multiple environmental factors influence flowering, including temperature. Both a continuously increased ambient temperature as well as temporary

  5. To flower or not to flower, a temperature-sensitive decision : Characterization of flowering responses at high ambient temperature in Arabidopsis thaliana

    NARCIS (Netherlands)

    Rodenburg, Nicole

    2015-01-01

    To maximize fitness, plants use environmental cues to optimize growth processes. One of the processes under strong environmental regulation is flowering. Multiple environmental factors influence flowering, including temperature. Both a continuously increased ambient temperature as well as temporary

  6. Factors affecting date of implantation, parturition, and den entry estimated from activity and body temperature in free-ranging brown bears.

    Directory of Open Access Journals (Sweden)

    Andrea Friebe

    Full Text Available Knowledge of factors influencing the timing of reproduction is important for animal conservation and management. Brown bears (Ursus arctos are able to vary the birth date of their cubs in response to their fat stores, but little information is available about the timing of implantation and parturition in free-ranging brown bears. Body temperature and activity of pregnant brown bears is higher during the gestation period than during the rest of hibernation and drops at parturition. We compared mean daily body temperature and activity levels of pregnant and nonpregnant females during preimplantation, gestation, and lactation. Additionally we tested whether age, litter size, primiparity, environmental conditions, and the start of hibernation influence the timing of parturition. The mean date of implantation was 1 December (SD = 12, the mean date of parturition was 26 January (SD = 12, and the mean duration of the gestation period was 56 days (SD = 2. The body temperature of pregnant females was higher during the gestation and lactation periods than that of nonpregnant bears. The body temperature of pregnant females decreased during the gestation period. Activity recordings were also used to determine the date of parturition. The parturition dates calculated with activity and body temperature data did not differ significantly and were the same in 50% of the females. Older females started hibernation earlier. The start of hibernation was earlier during years with favorable environmental conditions. Dates of parturition were later during years with good environmental conditions which was unexpected. We suggest that free-ranging pregnant brown bears in areas with high levels of human activities at the beginning of the denning period, as in our study area, might prioritize investing energy in early denning than in early parturition during years with favorable environmental conditions, as a strategy to prevent disturbances caused by human.

  7. Factors affecting date of implantation, parturition, and den entry estimated from activity and body temperature in free-ranging brown bears.

    Science.gov (United States)

    Friebe, Andrea; Evans, Alina L; Arnemo, Jon M; Blanc, Stéphane; Brunberg, Sven; Fleissner, Günther; Swenson, Jon E; Zedrosser, Andreas

    2014-01-01

    Knowledge of factors influencing the timing of reproduction is important for animal conservation and management. Brown bears (Ursus arctos) are able to vary the birth date of their cubs in response to their fat stores, but little information is available about the timing of implantation and parturition in free-ranging brown bears. Body temperature and activity of pregnant brown bears is higher during the gestation period than during the rest of hibernation and drops at parturition. We compared mean daily body temperature and activity levels of pregnant and nonpregnant females during preimplantation, gestation, and lactation. Additionally we tested whether age, litter size, primiparity, environmental conditions, and the start of hibernation influence the timing of parturition. The mean date of implantation was 1 December (SD = 12), the mean date of parturition was 26 January (SD = 12), and the mean duration of the gestation period was 56 days (SD = 2). The body temperature of pregnant females was higher during the gestation and lactation periods than that of nonpregnant bears. The body temperature of pregnant females decreased during the gestation period. Activity recordings were also used to determine the date of parturition. The parturition dates calculated with activity and body temperature data did not differ significantly and were the same in 50% of the females. Older females started hibernation earlier. The start of hibernation was earlier during years with favorable environmental conditions. Dates of parturition were later during years with good environmental conditions which was unexpected. We suggest that free-ranging pregnant brown bears in areas with high levels of human activities at the beginning of the denning period, as in our study area, might prioritize investing energy in early denning than in early parturition during years with favorable environmental conditions, as a strategy to prevent disturbances caused by human.

  8. Risk factors for obesity at age 3 in Alaskan children, including the role of beverage consumption: results from Alaska PRAMS 2005-2006 and its three-year follow-up survey, CUBS, 2008-2009.

    Science.gov (United States)

    Wojcicki, Janet M; Young, Margaret B; Perham-Hester, Katherine A; de Schweinitz, Peter; Gessner, Bradford D

    2015-01-01

    Prenatal and early life risk factors are associated with childhood obesity. Alaska Native children have one of the highest prevalences of childhood obesity of all US racial/ethnic groups. Using the Pregnancy Risk Assessment Monitoring System (PRAMS) and the follow-up survey at 3 years of age (CUBS), we evaluated health, behavioral, lifestyle and nutritional variables in relation to obesity (95th percentile for body mass index (BMI)) at 3 years of age. Multivariate logistic regression modeling was conducted using Stata 12.0 to evaluate independent risk factors for obesity in non-Native and Alaska Native children. We found an obesity prevalence of 24.9% in all Alaskan and 42.2% in Alaska Native 3 year olds. Among Alaska Native children, obesity prevalence was highest in the Northern/Southwest part of the state (51.6%, 95%CI (42.6-60.5)). Independent predictive factors for obesity at age 3 years in Alaska non-Native children were low income (obesity (OR 2.01, 95%CI 1.01-4.01) and longer duration of breastfeeding was protective (OR 0.95, 95%CI 0.91-0.995). Among Alaska Native children, predictive factors were witnessing domestic violence/abuse as a 3 year-old (OR 2.28, 95%CI 1.17-7.60). Among obese Alaska Native children, there was an increased daily consumption of energy dense beverages in the Northern/Southwest region of the state, which may explain higher rates of obesity in this part of the state. The high prevalence of obesity in Alaska Native children may be explained by differences in lifestyle patterns and food consumption in certain parts of the state, specifically the Northern/Southwest region, which have higher consumption of energy dense beverages.

  9. A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil

    OpenAIRE

    Etienne, M. C.; Pivot, X; Formento, J. L.; Bensadoun, R J; Formento, P.; Dassonville, O; Francoual, M.; Poissonnet, G.; Fontana, X; Schneider, M.; Demard, F.; Milano, G

    1999-01-01

    The prognostic value of tumoural epidermal growth factor receptor (EGFR), p53, thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) was analysed on 82 advanced head and neck cancer patients (71 men, 11 women; mean age 59). Induction treatment was cisplatin–5-FU ± folinic acid (61 patients, Chem group) or concomitant cisplatin–5-FU–radiotherapy (21 patients, RChem group). EGFR (binding assay), p53 protein (Sangtec immunoluminometric assay), TS and DPD activities (radioenzymatic ...

  10. Risk Factors for Obesity at Age 3 in Alaskan Children, Including the Role of Beverage Consumption: Results from Alaska PRAMS 2005-2006 and Its Three-Year Follow-Up Survey, CUBS, 2008-2009

    OpenAIRE

    Wojcicki, Janet M; Young, Margaret B.; Katherine A Perham-Hester; de Schweinitz, Peter; Bradford D Gessner

    2015-01-01

    Background Prenatal and early life risk factors are associated with childhood obesity. Alaska Native children have one of the highest prevalences of childhood obesity of all US racial/ethnic groups. Methods Using the Pregnancy Risk Assessment Monitoring System (PRAMS) and the follow-up survey at 3 years of age (CUBS), we evaluated health, behavioral, lifestyle and nutritional variables in relation to obesity (95th percentile for body mass index (BMI)) at 3 years of age. Multivariate logistic ...

  11. Risk Factors for Obesity at Age 3 in Alaskan Children, Including the Role of Beverage Consumption: Results from Alaska PRAMS 2005-2006 and Its Three-Year Follow-Up Survey, CUBS, 2008-2009

    Science.gov (United States)

    Wojcicki, Janet M.; Young, Margaret B.; Perham-Hester, Katherine A.; de Schweinitz, Peter; Gessner, Bradford D.

    2015-01-01

    Background Prenatal and early life risk factors are associated with childhood obesity. Alaska Native children have one of the highest prevalences of childhood obesity of all US racial/ethnic groups. Methods Using the Pregnancy Risk Assessment Monitoring System (PRAMS) and the follow-up survey at 3 years of age (CUBS), we evaluated health, behavioral, lifestyle and nutritional variables in relation to obesity (95th percentile for body mass index (BMI)) at 3 years of age. Multivariate logistic regression modeling was conducted using Stata 12.0 to evaluate independent risk factors for obesity in non-Native and Alaska Native children. Results We found an obesity prevalence of 24.9% in all Alaskan and 42.2% in Alaska Native 3 year olds. Among Alaska Native children, obesity prevalence was highest in the Northern/Southwest part of the state (51.6%, 95%CI (42.6-60.5)). Independent predictive factors for obesity at age 3 years in Alaska non-Native children were low income (obesity (OR 2.01, 95%CI 1.01-4.01) and longer duration of breastfeeding was protective (OR 0.95, 95%CI 0.91-0.995). Among Alaska Native children, predictive factors were witnessing domestic violence/abuse as a 3 year-old (OR 2.28, 95%CI 1.17-7.60). Among obese Alaska Native children, there was an increased daily consumption of energy dense beverages in the Northern/Southwest region of the state, which may explain higher rates of obesity in this part of the state. Conclusions The high prevalence of obesity in Alaska Native children may be explained by differences in lifestyle patterns and food consumption in certain parts of the state, specifically the Northern/Southwest region, which have higher consumption of energy dense beverages. PMID:25793411

  12. Measurements of VOC/SVOC emission factors from burning incenses in an environmental test chamber: influence of temperature, relative humidity, and air exchange rate.

    Science.gov (United States)

    Manoukian, A; Buiron, D; Temime-Roussel, B; Wortham, H; Quivet, E

    2016-04-01

    This study investigates the influence of three environmental indoor parameters (i.e., temperature, relative humidity, and air exchange rate) on the emission of 13 volatile organic compounds (VOCs) and semi-volatile organic compounds (SVOCs) during incense burning. Experiments have been carried out using an environmental test chamber. Statistical results from a classical two-level full factorial design highlight the predominant effect of ventilation on emission factors. The higher the ventilation, the higher the emission factor. Moreover, thanks to these results, an estimation of the concentration range for the compounds under study can be calculated and allows a quick look of indoor pollution induced by incense combustion. Carcinogenic substances (i.e., benzene, benzo(a)pyrene, and formaldehyde) produced from the incense combustion would be predicted in typical living indoors conditions to reach instantaneous concentration levels close to or higher than air quality exposure threshold values.

  13. Risk factors for obesity at age 3 in Alaskan children, including the role of beverage consumption: results from Alaska PRAMS 2005-2006 and its three-year follow-up survey, CUBS, 2008-2009.

    Directory of Open Access Journals (Sweden)

    Janet M Wojcicki

    Full Text Available Prenatal and early life risk factors are associated with childhood obesity. Alaska Native children have one of the highest prevalences of childhood obesity of all US racial/ethnic groups.Using the Pregnancy Risk Assessment Monitoring System (PRAMS and the follow-up survey at 3 years of age (CUBS, we evaluated health, behavioral, lifestyle and nutritional variables in relation to obesity (95th percentile for body mass index (BMI at 3 years of age. Multivariate logistic regression modeling was conducted using Stata 12.0 to evaluate independent risk factors for obesity in non-Native and Alaska Native children.We found an obesity prevalence of 24.9% in all Alaskan and 42.2% in Alaska Native 3 year olds. Among Alaska Native children, obesity prevalence was highest in the Northern/Southwest part of the state (51.6%, 95%CI (42.6-60.5. Independent predictive factors for obesity at age 3 years in Alaska non-Native children were low income (<$10,000 in the year before the child was born (OR 3.94, 95%CI 1.22--17.03 and maternal pre-pregnancy obesity (OR 2.01, 95%CI 1.01-4.01 and longer duration of breastfeeding was protective (OR 0.95, 95%CI 0.91-0.995. Among Alaska Native children, predictive factors were witnessing domestic violence/abuse as a 3 year-old (OR 2.28, 95%CI 1.17-7.60. Among obese Alaska Native children, there was an increased daily consumption of energy dense beverages in the Northern/Southwest region of the state, which may explain higher rates of obesity in this part of the state.The high prevalence of obesity in Alaska Native children may be explained by differences in lifestyle patterns and food consumption in certain parts of the state, specifically the Northern/Southwest region, which have higher consumption of energy dense beverages.

  14. Low temperature aluminum soldering analysis

    Energy Technology Data Exchange (ETDEWEB)

    Peterkort, W.G.

    1976-09-01

    The investigation of low temperature aluminum soldering included the collection of spread factor and dihedral angle data for several solder alloys and a study of flux effects on aluminum. Selected solders were subjected to environmental tests and evaluated on the basis of tensile strength, joint resistance, visual appearance, and metallurgical analysis. A production line method for determining adequate flux removal was developed.

  15. Effects of temperature and diet on length-weight relationship and condition factor of the juvenile Malabar blood snapper (Lutjanus malabaricus Bloch & Schneider, 1801).

    Science.gov (United States)

    Mazumder, Sabuj Kanti; Das, Simon Kumar; Bakar, Yosni; Ghaffar, Mazlan Abd

    2016-08-01

    In this study we aimed to analyze the effects of water temperature and diet on the length-weight relationship and condition of juvenile Malabar blood snapper Lutjanus malabaricus over a 30-d experimental period. The experiment was conducted in the laboratory using a flow-through-sea-water system. The fish were subjected to four different temperatures (22, 26, 30, and 34 °C) and two diets (commercial pellet and natural shrimp). Fish were fed twice daily. L. malabaricus exhibited negative allometric growth (b3) at 30 °C fed with shrimp diet, which indicated that fish weight increases faster than their length. The rest of the temperatures represented negative allometric growth (b<3) on both diet, meaning that fish became lighter with increasing size. The condition factors in the initial and final measurements were greater than 1, indicating the state of health of the fish, except for those fed on a pellet diet at 34 °C. However, the best condition was obtained at 30 °C on both diets. Nevertheless, diets did not have a significant effect on growth and condition of juvenile L. malabaricus. The data obtained from this study suggested culturing L. malabaricus at 30 °C and feeding on the pellet or shrimp diet, which will optimize the overall production and condition of this commercially important fish species.

  16. Effect of dietary manganese on antioxidant status and expressions of heat shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures.

    Science.gov (United States)

    Zhu, Yong-Wen; Lu, Lin; Li, Wen-Xiang; Zhang, Li-Yang; Ji, Cheng; Lin, Xi; Liu, Hsiao-Ching; Odle, Jack; Luo, Xu-Gang

    2016-12-01

    To investigate the effect of Mn on antioxidant status and on the expressions of heat shock proteins/factors in tissues of laying broiler breeders subjected to heat challenge, we used a completely randomised design (n 6) with a factorial arrangement of 2 environmental temperatures (normal, 21±1°C, and high, 32±1°C)×3 dietary Mn treatments (a Mn-unsupplemented basal diet (CON), or a basal diet supplemented with 120 mg Mn/kg diet, either as inorganic Mn sulphate (iMn) or as organic Mn proteinate (oMn)). There were no interactions (P>0·10) between environmental temperature and dietary Mn in any of the measured indices. High temperature decreased (P<0·003) Mn content, and also tended (P=0·07) to decrease Cu Zn superoxide dismutase (CuZnSOD) activity in the liver and heart. However, an increased Mn superoxide dismutase (MnSOD) activity (P<0·05) and a slight increase in malondialdehyde level (P=0·06) were detected in breast muscle. Up-regulated (P<0·05) expressions of heat shock factor 1 (HSF1) and HSF3 mRNA and heat shock protein 70 (HSP70) mRNA and protein were found in all three tissues. Broiler breeders fed either iMn or oMn had higher tissue Mn content (P<0·0001), heart MnSOD and CuZnSOD activities (P<0·01) and breast muscle MnSOD protein levels (P<0·05), and lower (P<0·05) breast muscle HSP70 mRNA and protein levels compared with those fed CON. Broiler breeders fed oMn had higher (P<0·03) bone Mn content than those fed iMn. These results indicate that high temperature decreases Mn retention and increases HSP70, HSF1 and HSF3 expressions in the tissues of laying broiler breeders. Furthermore, dietary supplementation with Mn in either source may enhance the heart's antioxidant ability and inhibit the expression of HSP70 in breast muscle. Finally, the organic Mn appears to be more available than inorganic Mn for bone in laying broiler breeders regardless of environmental temperatures.

  17. Unprecedented quality factors at accelerating gradients up to 45 MVm-1 in niobium superconducting resonators via low temperature nitrogen infusion

    Science.gov (United States)

    Grassellino, A.; Romanenko, A.; Trenikhina, Y.; Checchin, M.; Martinello, M.; Melnychuk, O. S.; Chandrasekaran, S.; Sergatskov, D. A.; Posen, S.; Crawford, A. C.; Aderhold, S.; Bice, D.

    2017-09-01

    We report the finding of new surface treatments that permits one to manipulate the niobium resonator nitrogen content in the first few nanometers in a controlled way, and the resonator fundamental Mattis-Bardeen surface resistance and residual resistance accordingly. In particular, we find surface ‘infusion’ conditions that systematically (a) increase the quality factor of these 1.3 GHz superconducting radio frequency (SRF) bulk niobium resonators, up to very high gradients; (b) increase the achievable accelerating gradient of the cavity compared to its own baseline with state-of-the-art surface processing. Cavities subject to the new surface process have more than two times the state-of-the-art Q at 2 K for accelerating fields >35 MVm-1. Moreover, very high accelerating gradients ˜45 MVm-1 are repeatedly reached, which correspond to peak magnetic surface fields of 190 mT, among the highest measured for bulk niobium cavities. These findings open the opportunity to tailor the surface impurity content distribution to maximize performance in Q and gradients, and have therefore very important implications on future performance and cost of SRF based accelerators. They also help deepen the understanding of the physics of the RF niobium cavity surface.

  18. The pyrH gene of Lactococcus lactis subsp. cremoris encoding UMP kinase is transcribed as part of an operon including the frr1 gene encoding ribosomal recycling factor

    DEFF Research Database (Denmark)

    Wadskov-Hansen, Steen Lüders; Martinussen, Jan; Hammer, Karin

    2000-01-01

    establishing the ability of the encoded protein to synthesize UDP. The pyrH gene in L. lactis is flanked downstream by frr1 encoding ribosomal recycling factor 1 and upstream by an open reading frame, orfA, of unknown function. The three genes were shown to constitute an operon transcribed in the direction orf......A-pyrH-frr1 from a promoter immediately in front of orfA. This operon belongs to an evolutionary highly conserved gene cluster, since the organization of pyrH on the chromosomal level in L. lactis shows a high resemblance to that found in Bacillus subtilis as well as in Escherichia coli and several other...

  19. Brain temperature and exercise performance.

    Science.gov (United States)

    Nybo, Lars

    2012-03-01

    Events arising within the central nervous system seem to be a major factor in the aetiology of hyperthermia-induced fatigue. Thus, various studies with superimposed electrical nerve stimulation or transcranial magnetic stimulation have shown that both passive and exercise-induced hyperthermia will impair voluntary motor activation during sustained maximal contractions. In humans, the brain temperature increases in parallel with that of the body core, making it very difficult to evaluate the independent effect of the cerebral temperature. Experiments with separate manipulation of the brain temperature in exercising goats indicate that excessive brain hyperthermia will directly affect motor performance. However, several homeostatic changes arise in parallel with hyperthermia, including factors that may influence both peripheral and central fatigue, and it is likely that these changes interact with the inhibitory effect of an elevated brain temperature.

  20. Dark-leaved willow (Salix myrsinifolia) is resistant to three-factor (elevated CO2, temperature and UV-B-radiation) climate change.

    Science.gov (United States)

    Paajanen, Ria; Julkunen-Tiitto, Riitta; Nybakken, Line; Petrelius, Mari; Tegelberg, Riitta; Pusenius, Jyrki; Rousi, Matti; Kellomäki, Seppo

    2011-04-01

    Elevated carbon dioxide (CO2 ), temperature (T) and ultraviolet-B (UV-B) radiation may affect plant growth and secondary chemistry in different directions, but the effect of the combination of the three factors has seldom been tested. Here, we grew four dark-leaved willow (Salix myrsinifolia) clones under combinations of ambient or elevated CO2, T and UV-B radiation in top-closed chambers for 7 wk. Elevated UV-B had no effects on growth or phenolic compounds, and there were no significant interactions between UV-B, CO2 and T. CO2 alone increased most growth parameters, but the magnitude of the effect varied among the clones. Total phenolics increased at elevated CO2 , whereas they decreased at elevated T. The responses varied between the clones. The results imply that dark-leaved willow are fairly resistant to the applied three-factor climate change, probably because of high constitutive defense. However, the interactions between clone and climate change factors implies that some clones are more susceptible than the species as a whole.

  1. The VITRO Score (Von Willebrand Factor Antigen/Thrombocyte Ratio as a New Marker for Clinically Significant Portal Hypertension in Comparison to Other Non-Invasive Parameters of Fibrosis Including ELF Test.

    Directory of Open Access Journals (Sweden)

    Stephanie Hametner

    Full Text Available Clinically significant portal hypertension (CSPH, defined as hepatic venous pressure gradient (HVPG ≥10 mmHg, causes major complications. HVPG is not always available, so a non-invasive tool to diagnose CSPH would be useful. VWF-Ag can be used to diagnose. Using the VITRO score (the VWF-Ag/platelet ratio instead of VWF-Ag itself improves the diagnostic accuracy of detecting cirrhosis/ fibrosis in HCV patients.This study tested the diagnostic accuracy of VITRO score detecting CSPH compared to HVPG measurement.All patients underwent HVPG testing and were categorised as CSPH or no CSPH. The following patient data were determined: CPS, D'Amico stage, VITRO score, APRI and transient elastography (TE.The analysis included 236 patients; 170 (72% were male, and the median age was 57.9 (35.2-76.3; 95% CI. Disease aetiology included ALD (39.4%, HCV (23.4%, NASH (12.3%, other (8.1% and unknown (11.9%. The CPS showed 140 patients (59.3% with CPS A; 56 (23.7% with CPS B; and 18 (7.6% with CPS C. 136 patients (57.6% had compensated and 100 (42.4% had decompensated cirrhosis; 83.9% had HVPG ≥10 mmHg. The VWF-Ag and the VITRO score increased significantly with worsening HVPG categories (P<0.0001. ROC analysis was performed for the detection of CSPH and showed AUC values of 0.92 for TE, 0.86 for VITRO score, 0.79 for VWF-Ag, 0.68 for ELF and 0.62 for APRI.The VITRO score is an easy way to diagnose CSPH independently of CPS in routine clinical work and may improve the management of patients with cirrhosis.

  2. Recent developments in superconducting materials including ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Tachikawa, Kyoji

    1987-06-01

    This report describes the history of superconduction starting in 1911, when the superconducting phenomenon was first observed in murcury, until the recent discovery of superconducting materials with high critical temperatures. After outlining the BCS theory, basic characteristics are discussed including the critical temperature, magnetic field and current density to be reached for realizing the superconducting state. Various techniques for practical superconducting materials are discussed, including methods for producing extra fine multiconductor wires from such superconducting alloys as Nb-Ti, intermetallic Nb/sub 3/Sn compound and V/sub 3/Ga, as well as methods for producing wires of Nb/sub 3/Al, Nb/sub 3/(Al, Ge) and Nb/sub 3/Ge such as continuous melt quenching, electron beam irradiation, laser beam irradiation and chemical evaporation. Characteristics of superconducting ceramics are described, along with their applications including superconducting magnets and superconducting elements. (15 figs, 1 tab, 19 refs)

  3. Electronic structure and Landé g-factor of a quantum ring in the presence of spin-orbit coupling: Temperature and Zeeman effect

    Science.gov (United States)

    Zamani, A.; Setareh, F.; Azargoshasb, T.; Niknam, E.

    2017-10-01

    A wide variety of semiconductor nanostructures have been fabricated experimentally and both theoretical and experimental investigations of their features imply the great role they have in new generation technological devices. However, mathematical modeling provide a powerful means due to definitive goal of predicting the features and understanding of such structures behavior under different circumstances. Therefore, effective Hamiltonian for an electron in a quantum ring with axial symmetry in the presence of both Rashba and Dresselhaus spin-orbit interactions (SOI) is derived. Here we report our study of the electronic structure and electron g-factor in the presence of spin-orbit (SO) couplings under the influence of external magnetic field at finite temperature. This investigation shows that, when Rashba and Dresselhaus couplings are simultaneously present, the degeneracy is removed and energy levels split into two branches. Furthermore, with enhancing the applied magnetic field, separation of former degenerate levels increases and also avoided crossings (anti-crossing) in the energy spectra is detected. It is also discussed how the energy levels of the system can be adjusted with variation of temperature as well as the magnetic field and geometrical sizes.

  4. What is the impact of obtaining medical clearance to participate in a randomised controlled trial examining a physical activity intervention on the socio-demographic and risk factor profiles of included participants?

    Science.gov (United States)

    Duncan, Mitch J; Rosenkranz, Richard R; Vandelanotte, Corneel; Caperchione, Cristina M; Rebar, Amanda L; Maeder, Anthony J; Tague, Rhys; Savage, Trevor N; van Itallie, Anetta; Mummery, W Kerry; Kolt, Gregory S

    2016-12-07

    Requiring individuals to obtain medical clearance to exercise prior to participation in physical activity interventions is common. The impact this has on the socio-demographic characteristic profiles of participants who end up participating in the intervention is not clear. As part of the multi-component eligibility screening for inclusion in a three-arm randomised controlled trial examining the efficacy of a web-based physical activity intervention, individuals interested in participating were required to complete the Physical Activity Readiness Questionnaire (PAR-Q). The PAR-Q identified individuals as having lower or higher risk. Higher-risk individuals were required to obtain medical exercise clearance prior to enrolment. Comparisons of the socio-demographic characteristics of the lower- and higher-risk individuals were performed using t tests and chi-square tests (p = 0.05). A total of 1244 individuals expressed interest in participating, and 432 were enrolled without needing to undergo further screening. Of the 251 individuals required to obtain medical clearance, 148 received clearance, 15 did not receive clearance and 88 did not return any form of clearance. A total of 105 individuals were enrolled after obtaining clearance, and the most frequent reason for being required to seek clearance was for using blood pressure/heart condition medication. Higher-risk individuals were significantly older, had a higher body mass index and engaged in more sedentary behaviour than lower-risk individuals. Use of more inclusive participant screening protocols that maintain high levels of participant safety are encouraged. Allowing individuals to obtain medical clearance to participate can result in including a more diverse population likely to benefit most from participation. Australian New Zealand Clinical Trials Registry ( ACTRN12611000157976 ). Registered on 9 February 2011.

  5. Examination and experimental constraints of the stellar reaction rate factor $N_A < \\sigma v >$ of the $^{18}$Ne($\\alpha$,$p$)$^{21}$Na reaction at temperatures of X-Ray Bursts

    CERN Document Server

    Mohr, P

    2013-01-01

    The $^{18}$Ne($\\alpha$,$p$)$^{21}$Na reaction is one key for the break-out from the hot CNO-cycles to the $rp$-process. Recent papers have provided reaction rate factors $N_A $ which are discrepant by at least one order of magnitude. The compatibility of the latest experimental results is tested, and a partial explanation for the discrepant $N_A$ is given. A new rate factor is derived from the combined analysis of all available data. The new rate factor is located slightly below the higher rate factor by Matic {\\it et al.}\\ at low temperatures and significantly below at higher temperatures whereas it is about a factor of five higher than the lower rate factor recently published by Salter {\\it et al.}

  6. Multifactorial effects of ambient temperature, precipitation, farm management, and environmental factors determine the level of generic Escherichia coli contamination on preharvested spinach.

    Science.gov (United States)

    Park, Sangshin; Navratil, Sarah; Gregory, Ashley; Bauer, Arin; Srinath, Indumathi; Szonyi, Barbara; Nightingale, Kendra; Anciso, Juan; Jun, Mikyoung; Han, Daikwon; Lawhon, Sara; Ivanek, Renata

    2015-04-01

    A repeated cross-sectional study was conducted to identify farm management, environment, weather, and landscape factors that predict the count of generic Escherichia coli on spinach at the preharvest level. E. coli was enumerated for 955 spinach samples collected on 12 farms in Texas and Colorado between 2010 and 2012. Farm management and environmental characteristics were surveyed using a questionnaire. Weather and landscape data were obtained from National Resources Information databases. A two-part mixed-effect negative binomial hurdle model, consisting of a logistic and zero-truncated negative binomial part with farm and date as random effects, was used to identify factors affecting E. coli counts on spinach. Results indicated that the odds of a contamination event (non-zero versus zero counts) vary by state (odds ratio [OR] = 108.1). Odds of contamination decreased with implementation of hygiene practices (OR = 0.06) and increased with an increasing average precipitation amount (mm) in the past 29 days (OR = 3.5) and the application of manure (OR = 52.2). On contaminated spinach, E. coli counts increased with the average precipitation amount over the past 29 days. The relationship between E. coli count and the average maximum daily temperature over the 9 days prior to sampling followed a quadratic function with the highest bacterial count at around 24°C. These findings indicate that the odds of a contamination event in spinach are determined by farm management, environment, and weather factors. However, once the contamination event has occurred, the count of E. coli on spinach is determined by weather only.

  7. Temperature metrology

    Science.gov (United States)

    Fischer, J.; Fellmuth, B.

    2005-05-01

    The majority of the processes used by the manufacturing industry depend upon the accurate measurement and control of temperature. Thermal metrology is also a key factor affecting the efficiency and environmental impact of many high-energy industrial processes, the development of innovative products and the health and safety of the general population. Applications range from the processing, storage and shipment of perishable foodstuffs and biological materials to the development of more efficient and less environmentally polluting combustion processes for steel-making. Accurate measurement and control of temperature is, for instance, also important in areas such as the characterization of new materials used in the automotive, aerospace and semiconductor industries. This paper reviews the current status of temperature metrology. It starts with the determination of thermodynamic temperatures required on principle because temperature is an intensive quantity. Methods to determine thermodynamic temperatures are reviewed in detail to introduce the underlying physical basis. As these methods cannot usually be applied for practical measurements the need for a practical temperature scale for day-to-day work is motivated. The International Temperature Scale of 1990 and the Provisional Low Temperature Scale PLTS-2000 are described as important parts of the International System of Units to support science and technology. Its main importance becomes obvious in connection with industrial development and international markets. Every country is strongly interested in unique measures, in order to guarantee quality, reproducibility and functionability of products. The eventual realization of an international system, however, is only possible within the well-functioning organization of metrological laboratories. In developed countries the government established scientific institutes have certain metrological duties, as, for instance, the maintenance and dissemination of national

  8. Temperature and cholera toxin B are factors that influence formation of membrane nanotubes in RT4 and T24 urothelial cancer cell lines

    Directory of Open Access Journals (Sweden)

    Doron Kabaso

    2011-03-01

    Full Text Available Doron Kabaso1*, Maruša Lokar1*, Veronika Kralj-Iglic2, Peter Veranic3, Aleš Iglic11Laboratory of Biophysics, Faculty of Electrical Engineering, 2Laboratory of Clinical Biophysics, Faculty of Medicine, 3Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; *These two authors equally share the first authorshipAbstract: The growth of membrane nanotubes is crucial for intercellular communication in both normal development and pathological conditions. Therefore, identifying factors that influence their stability and formation are important for both basic research and in development of potential treatments of pathological states. Here we investigate the effect of cholera toxin B (CTB and temperature on two pathological model systems: urothelial cell line RT4, as a model system of a benign tumor, and urothelial cell line T24, as a model system of a metastatic tumor. In particular, the number of intercellular membrane nanotubes (ICNs; ie, membrane nanotubes that bridge neighboring cells was counted. In comparison with RT4 cells, we reveal a significantly higher number in the density of ICNs in T24 cells not derived from RT4 without treatments (P = 0.005, after 20 minutes at room temperature (P = 0.0007, and following CTB treatment (P = 0.000025. The binding of CTB to GM1–lipid complexes in membrane exvaginations or tips of membrane nanotubes may reduce the positive spontaneous (intrinsic curvature of GM1–lipid complexes, which may lead to lipid mediated attractive interactions between CTB–GM1–lipid complexes, their aggregation and consequent formation of enlarged spherical tips of nanotubes. The binding of CTB to GM1 molecules in the outer membrane leaflet of membrane exvaginations and tips of membrane nanotubes may also increase the area difference between the two leaflets and in this way facilitate the growth of membrane nanotubes.Keywords: cancer cells, membrane nanotubes, cholera toxin

  9. Overexpression of a novel cold-responsive transcript factor LcFIN1 from sheepgrass enhances tolerance to low temperature stress in transgenic plants.

    Science.gov (United States)

    Gao, Qiong; Li, Xiaoxia; Jia, Junting; Zhao, Pincang; Liu, Panpan; Liu, Zhujiang; Ge, Liangfa; Chen, Shuangyan; Qi, Dongmei; Deng, Bo; Lee, Byung-Hyun; Liu, Gongshe; Cheng, Liqin

    2016-03-01

    As a perennial forage crop broadly distributed in eastern Eurasia, sheepgrass (Leymus chinensis (Trin.) Tzvel) is highly tolerant to low-temperature stress. Previous report indicates that sheepgrass is able to endure as low as -47.5 °C,allowing it to survive through the cold winter season. However, due to the lack of sufficient studies, the underlying mechanism towards the extraordinary low-temperature tolerance is unclear. Although the transcription profiling has provided insight into the transcriptome response to cold stress, more detailed studies are required to dissect the molecular mechanism regarding the excellent abiotic stress tolerance. In this work, we report a novel transcript factor LcFIN1 (L. chinensis freezing-induced 1) from sheepgrass. LcFIN1 showed no homology with other known genes and was rapidly and highly induced by cold stress, suggesting that LcFIN1 participates in the early response to cold stress. Consistently, ectopic expression of LcFIN1 significantly increased cold stress tolerance in the transgenic plants, as indicated by the higher survival rate, fresh weight and other stress-related indexes after a freezing treatment. Transcriptome analysis showed that numerous stress-related genes were differentially expressed in LcFIN1-overexpressing plants, suggesting that LcFIN1 may enhance plant abiotic stress tolerance by transcriptional regulation. Electrophoretic mobility shift assays and CHIP-qPCR showed that LcCBF1 can bind to the CRT/DRE cis-element located in the promoter region of LcFIN1, suggesting that LcFIN1 is directly regulated by LcCBF1. Taken together, our results suggest that LcFIN1 positively regulates plant adaptation response to cold stress and is a promising candidate gene to improve crop cold tolerance. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

  10. Temperature Dependence of Thermal Conductivity of Nanofluids

    Institute of Scientific and Technical Information of China (English)

    LI Yu-Hua; QU Wei; FENG Jian-Chao

    2008-01-01

    Mechanism of thermal conductivity of nanofluids is analysed and calculated, including Brownian motion effects, particle agglomeration and viscosity, together influenced by temperature. The results show that only Brownian motion as reported is not enough to describe the temperature dependence of the thermal conductivity of nanofluids. The change of particle agglomeration and viscosity with temperature are also important factors. As temperature increases, the reduction of the particle surface energy would decrease the agglomeration of nanopartides, and the reduction of viscosity would improve the Brownian motion. The results agree well with the experimental data reported.

  11. Metabolic risk factors are associated with stiffness index, reflection index and finger skin temperature in children--Physical Activity and Nutrition in Children (PANIC) study.

    Science.gov (United States)

    Veijalainen, Aapo; Tompuri, Tuomo; Laitinen, Tomi; Lintu, Niina; Viitasalo, Anna; Laaksonen, David E; Jääskeläinen, Jarmo; Lakka, Timo A

    2013-01-01

    Childhood metabolic syndrome (MetS) has been found to predict adulthood MetS, type 2 diabetes and cardiovascular disease, emphasizing the early identification of children at increased risk of these diseases. Children with clustering of metabolic risk factors have been reported to have a mild arterial stiffness and endothelial dysfunction, but limited evidence is available from population-based samples of children. The associations of metabolic risk factors with arterial stiffness, tone and endothelial function were studied in 173 prepubertal children (90 girls) 6-8 years of age. MetS was assessed both by continuous MetScore and dichotomously. Stiffness index (SI), reflection index (RI) and finger skin temperature (FST) were measured before and after maximum exercise test, and percent change was calculated for RI (RI%Δ) and FST (FST%Δ). MetScore (r=0.26, P=0.001), fasting insulin (r=0.24, P=0.002), fasting triglycerides (r=0.20, P=0.009), systolic (SBP; r=0.24, P=0.002) and diastolic blood pressure (DBP; r=0.19, P=0.013) correlated with SI. MetScore (r=-0.17, P=0.024, r=0.21, P=0.006), waist circumference (r=-0.19, P=0.012, r=0.23, P=0.003) and SBP (r=-0.16, P=0.035, r=0.21, P=0.005) correlated with RI and FST. High-density lipoprotein cholesterol correlated with FST (r=-0.22, P=0.004) and FST%Δ (r=-0.24, P=0.002). RI decreased and FST increased with exercise (P<0.001). Waist circumference correlated inversely with RI%Δ in boys (r=-0.22, P=0.046) and directly with RI%Δ in girls (r=0.27, P=0.011). Metabolic risk factors are associated with arterial stiffness, tone and endothelial function in prepubertal children. 

  12. Theory including future not excluded

    DEFF Research Database (Denmark)

    Nagao, K.; Nielsen, H.B.

    2013-01-01

    We study a complex action theory (CAT) whose path runs over not only past but also future. We show that, if we regard a matrix element defined in terms of the future state at time T and the past state at time TA as an expectation value in the CAT, then we are allowed to have the Heisenberg equation......, Ehrenfest's theorem, and the conserved probability current density. In addition,we showthat the expectation value at the present time t of a future-included theory for large T - t and large t - T corresponds to that of a future-not-included theory with a proper inner product for large t - T. Hence, the CAT...

  13. Temperature and voltage dependence of barrier height and ideality factor in Au/0.07 graphene-doped PVA/n-Si structures

    Science.gov (United States)

    Altındal Yerişkin, S.; Balbaşı, M.; Demirezen, S.

    2017-01-01

    In this study, Au/0.07 graphene-doped PVA/n-Si structures were fabricated and current conduction mechanism in these structures were investigated in the temperature range of 80-380 K through forward bias current-voltage (I-V) measurements. Main electrical parameters were extracted from I-V data. Zero-bias barrier height (overline{Φ}_{B0} ) and ideality factor (n) were found strong functions of temperature and their values ranged from 0.234 eV and 4.98 (at 80 K) to 0.882 eV and 1.15 (at 380 K), respectively. Φ ap versus q/2kT plot was drawn to obtain an evidence of a Gaussian distribution of the barrier heights (BHs) and it revealed two distinct linear regions with different slopes and intercepts. The mean values of BH (Φ Bo) and zero-bias standard deviation (σ s ) were obtained from the intercept and slope of the linear regions of this plot as 1.30 eV and 0.16 V for the first region (280-380 K) and 0.74 eV and 0.085 V for the second region (80-240 K), respectively. Thus, the values of overline{Φ}_{B0} and effective Richardson constant (A*) were also found from the intercept and slope of the modified Richardson plot [ln(I s /T 2) - q 2 σ {/o 2} /2k 2 T 2 vs q/kT] as 1.31 eV and 130 A/cm2 K2 for the first region and 0.76 eV and 922 A/cm2 K2 for the second region, respectively. The value of A* for the first region was very close to the theoretical value for n-Si (112 A/cm2 K2). The energy density distribution profile of surface states (Nss) was also extracted from the forward bias I-V data by taking into account voltage dependent effective BH (Φe) and n.

  14. Few remarks on some factors in maintaining temperature of basement; Chikashitsu no hoonsei ni oyobosu shoyoin ni kansuru nisan no chiken

    Energy Technology Data Exchange (ETDEWEB)

    Inada, Y. [Ehime University, Ehime (Japan). Faculty of Engineering; Shimasaki, O. [Ehime University, Ehime (Japan); Ueda, T. [Takenaka Corp., Osaka (Japan); Matsumoto, T. [Nissan Construction Co. Ltd., Tokyo (Japan); Sugi, G.

    1998-06-21

    Noticing on temperature maintaining effect of a basement, three types of full scale model basements were used to measure temperature change in the surrounding ground and rooms in the basement and discuss effects of ground temperature variation on the basement. Thermal property values were derived on the surrounding ground affecting the temperature maintainability of the basement, and temperature analysis was performed on a model assuming the basement to discuss effects of difference in size occupying under the ground on change in room temperatures. Then, assuming a case of using heat insulating materials in the basement, discussions were given on the consumed energy required for air conditioning. Underground temperature has its change to decrease as the ground depth increases throughout a year, and particularly at depths greater than 50 cm, no daily temperature change can be seen. Because of this effect, the greater the underground occupying size in the basement, the smaller the temperature change. Distributions of heat diffusion rate, heat capacity, and heat conductivity can be estimated by deriving water content ratio distribution. When air conditioning is carried out in the basement, applying the heat insulating materials on the inner side of a room is more effective. Energy conservation may be expected because the room temperature is stabilized. 9 refs., 27 figs., 4 tabs.

  15. Biodiversity conservation including uncharismatic species

    DEFF Research Database (Denmark)

    Muñoz, Joaquin

    2007-01-01

    Recent papers mention ideas on the topics of biodiversity conservation strategies and priorities (Redford et al. 2003; Lamoreux et al. 2006; Rodrı´guez et al. 2006), the current status of biodiversity (Loreau et al. 2006), the obligations of conservation biologists regarding management policies...... (Chapron 2006; Schwartz 2006), and the main threats to biodiversity (including invasive species) (Bawa 2006). I suggest, however, that these articles do not really deal with biodiversity. Rather, they all focus on a few obviously charismatic groups (mammals, birds, some plants, fishes, human culture...

  16. Effects of temperature and diet on length-weight relationship and condition factor of the juvenile Malabar blood snapper (Lutjanus malabaricus Bloch & Schneider, 1801)

    Institute of Scientific and Technical Information of China (English)

    Sabuj Kanti MAZUMDER; Simon Kumar DAS; Yosni BAKAR; Mazlan Abd GHAFFAR

    2016-01-01

    In this study we aimed to analyze the effects of water temperature and diet on the length-weight rela-tionship and condition of juvenile Malabar blood snapperLutjanus malabaricus over a 30-d experimental period. The experiment was conducted in the laboratory using a flow-through-sea-water system. The fish were subjected to four different temperatures (22, 26, 30, and 34 °C) and two diets (commercial pelet and natural shrimp). Fish were fed twice daily.L. malabaricus exhibited negative alometric growth (b3) at 30 °C fed with shrimp diet, which indicated that fish weight increases faster than their length. The rest of the temperatures represented negative alometric growth (b<3) on both diet, meaning that fish became lighter with increasing size. The condition factors in the initial and final measurements were greater than 1, indicating the state of health of the fish, except for those fed on a pelet diet at 34 °C. However, the best condition was obtained at 30 °C on both diets. Nev-ertheless, diets did not have a significant effect on growth and condition of juvenileL. malabaricus. The data obtained from this study suggested culturing L. malabaricus at 30 °C and feeding on the pellet or shrimp diet, which wil optimize the overal production and condition of this commercialy important fish species.%题目:温度和喂食影响摩拉吧笛鲷体长体重关系和肥满度的研究目的:分析水温度和喂食对摩拉吧笛鲷体长体重关系和肥满度的影响。创新点:本研究采用条件可控的流通式海水系统,对摩拉吧笛鲷的体长体重关系和肥满度进行研究。方法:本研究使用流通式海水系统在实验室中实施,选取4种不同温度(22、26、30和34°C)和2种饮食条件(商业颗粒和自然虾米),每天喂食2次,比较鲷鱼体长体重关系和肥满度差异。结论:结果表明,摩拉吧笛鲷的最好饲养条件是30°C,而喂食种类对摩拉吧笛鲷的生长和肥满度

  17. FLUXNET2015 Dataset: Batteries included

    Science.gov (United States)

    Pastorello, G.; Papale, D.; Agarwal, D.; Trotta, C.; Chu, H.; Canfora, E.; Torn, M. S.; Baldocchi, D. D.

    2016-12-01

    The synthesis datasets have become one of the signature products of the FLUXNET global network. They are composed from contributions of individual site teams to regional networks, being then compiled into uniform data products - now used in a wide variety of research efforts: from plant-scale microbiology to global-scale climate change. The FLUXNET Marconi Dataset in 2000 was the first in the series, followed by the FLUXNET LaThuile Dataset in 2007, with significant additions of data products and coverage, solidifying the adoption of the datasets as a research tool. The FLUXNET2015 Dataset counts with another round of substantial improvements, including extended quality control processes and checks, use of downscaled reanalysis data for filling long gaps in micrometeorological variables, multiple methods for USTAR threshold estimation and flux partitioning, and uncertainty estimates - all of which accompanied by auxiliary flags. This "batteries included" approach provides a lot of information for someone who wants to explore the data (and the processing methods) in detail. This inevitably leads to a large number of data variables. Although dealing with all these variables might seem overwhelming at first, especially to someone looking at eddy covariance data for the first time, there is method to our madness. In this work we describe the data products and variables that are part of the FLUXNET2015 Dataset, and the rationale behind the organization of the dataset, covering the simplified version (labeled SUBSET), the complete version (labeled FULLSET), and the auxiliary products in the dataset.

  18. 低温煤热解焦油产率和品质影响因素研究%Influencing factors of coal tar yield and quality from low-temperature coal pyrolysis

    Institute of Scientific and Technical Information of China (English)

    苗青; 郑化安; 张生军; 李学强; 陈静升; 张志刚

    2014-01-01

    煤焦油是低温煤热解技术的主要产物,是重要的化工原料,其产率和品质是评价煤热解工艺的重要指标。从原煤性质(煤种和煤粒径)、热解反应器结构形式及热解工艺条件(原煤预处理、热解温度、压力、升温速率、停留时间、热解气氛及催化剂)等方面综合分析了煤热解焦油产率和品质的影响因素,认为通过优选煤种和热解反应器,对煤样进行适当预处理,选择合适的工艺操作条件和引入加氢催化热解等有助于提高焦油产率和品质。%Coal tar,the main product of low-temperature coal pyrolysis,is an essential chemical material.The yield and quality of coal tar is an important indicator to evaluate the pyrolysis.Investigate the influencing factors of coal tar yield and quality from the aspects of raw coal characteristics such as coal types and coal particle size,structure of pyrolysis reactors and technical conditions including raw coal pretreat-ment,reaction temperature and pressure,heating rate,gas residence time,reaction atmosphere and catalysts.The results show that the yield and quality of coal tar can be improved by using proper coal and pyrolysis reactors,choosing appropriate technical conditions,adopting cat-alytic hydrogenation pyrolysis and the like.

  19. Families classification including multiopposition asteroids

    Science.gov (United States)

    Milani, Andrea; Spoto, Federica; Knežević, Zoran; Novaković, Bojan; Tsirvoulis, Georgios

    2016-01-01

    In this paper we present the results of our new classification of asteroid families, upgraded by using catalog with > 500,000 asteroids. We discuss the outcome of the most recent update of the family list and of their membership. We found enough evidence to perform 9 mergers of the previously independent families. By introducing an improved method of estimation of the expected family growth in the less populous regions (e.g. at high inclination) we were able to reliably decide on rejection of one tiny group as a probable statistical fluke. Thus we reduced our current list to 115 families. We also present newly determined ages for 6 families, including complex 135 and 221, improving also our understanding of the dynamical vs. collisional families relationship. We conclude with some recommendations for the future work and for the family name problem.

  20. Influence factors research on three dimensional temperature field of the canned motor%一种屏蔽电动机的三维温度场及影响因素研究

    Institute of Scientific and Technical Information of China (English)

    李藏雪; 任智达; 路义萍; 孔祥旭

    2015-01-01

    In order to ensure the safe and stable operation of the canned motor, it is very necessary to make elaborative and numerical thermal calculation. In order to match the heat calculation of the heat ex-changer and the temperature field calculation of working condition for shielding motor , first , the temper-ature of motor internal and external cooling water was got by calculating heat balance and thermal transfer of external heat exchanger,and was used as a boundary conditions of three dimensional motor temperature field calculation. Then, a three -dimensional motor physical model was established, and mathematical control equations including internal turbulence flow and heat transfer were selected and were solved with finite volume method based on computational fluid dynamics,at the boundary condition which has been given according to the actual situation. The temperature distribution characteristics were obtained. The in-fluence of related factors on temperature field was analyzed. The result shows that,the heat on both ends of the stator of copper winding pass to internal and external cooling waters by iron core through the ther-mal conduction mainly. Increasing the thermal conductivity value of axial and radial direction of iron core material is helpful to reduce the peak temperature. The results provide reference for cooling calculation and design of canned motors.%为了保证屏蔽电机能够长期稳定的安全运行,进行精细化、数值化热计算是非常必要的.为使换热器热计算与屏蔽电机温度场计算工况对应,首先针对外置换热器进行热平衡及传热计算,得到电机内、外部冷却进水的温度,作为屏蔽电机内三维温度场计算的边界条件,然后,建立电机三维物理模型,选取内部湍流流动及传热的数学控制方程及模型,按照实际给出边界条件,采用基于计算流体力学( CFD)原理的有限体积法进行求解,得到温度分布特征,分析了

  1. Analytic Couple Modeling Introducing Device Design Factor, Fin Factor, Thermal Diffusivity Factor, and Inductance Factor

    Science.gov (United States)

    Mackey, Jon; Sehirlioglu, Alp; Dynys, Fred

    2014-01-01

    A set of convenient thermoelectric device solutions have been derived in order to capture a number of factors which are previously only resolved with numerical techniques. The concise conversion efficiency equations derived from governing equations provide intuitive and straight-forward design guidelines. These guidelines allow for better device design without requiring detailed numerical modeling. The analytical modeling accounts for factors such as i) variable temperature boundary conditions, ii) lateral heat transfer, iii) temperature variable material properties, and iv) transient operation. New dimensionless parameters, similar to the figure of merit, are introduced including the device design factor, fin factor, thermal diffusivity factor, and inductance factor. These new device factors allow for the straight-forward description of phenomenon generally only captured with numerical work otherwise. As an example a device design factor of 0.38, which accounts for thermal resistance of the hot and cold shoes, can be used to calculate a conversion efficiency of 2.28 while the ideal conversion efficiency based on figure of merit alone would be 6.15. Likewise an ideal couple with efficiency of 6.15 will be reduced to 5.33 when lateral heat is accounted for with a fin factor of 1.0.

  2. SKIRT: Stellar Kinematics Including Radiative Transfer

    Science.gov (United States)

    Baes, Maarten; Dejonghe, Herwig; Davies, Jonathan

    2011-09-01

    SKIRT is a radiative transfer code based on the Monte Carlo technique. The name SKIRT, acronym for Stellar Kinematics Including Radiative Transfer, reflects the original motivation for its creation: it has been developed to study the effects of dust absorption and scattering on the observed kinematics of dusty galaxies. In a second stage, the SKIRT code was extended with a module to self-consistently calculate the dust emission spectrum under the assumption of local thermal equilibrium. This LTE version of SKIRT has been used to model the dust extinction and emission of various types of galaxies, as well as circumstellar discs and clumpy tori around active galactic nuclei. A new, extended version of SKIRT code can perform efficient 3D radiative transfer calculations including a self-consistent calculation of the dust temperature distribution and the associated FIR/submm emission with a full incorporation of the emission of transiently heated grains and PAH molecules.

  3. Including Magnetostriction in Micromagnetic Models

    Science.gov (United States)

    Conbhuí, Pádraig Ó.; Williams, Wyn; Fabian, Karl; Nagy, Lesleis

    2016-04-01

    The magnetic anomalies that identify crustal spreading are predominantly recorded by basalts formed at the mid-ocean ridges, whose magnetic signals are dominated by iron-titanium-oxides (Fe3-xTixO4), so called "titanomagnetites", of which the Fe2.4Ti0.6O4 (TM60) phase is the most common. With sufficient quantities of titanium present, these minerals exhibit strong magnetostriction. To date, models of these grains in the pseudo-single domain (PSD) range have failed to accurately account for this effect. In particular, a popular analytic treatment provided by Kittel (1949) for describing the magnetostrictive energy as an effective increase of the anisotropy constant can produce unphysical strains for non-uniform magnetizations. I will present a rigorous approach based on work by Brown (1966) and by Kroner (1958) for including magnetostriction in micromagnetic codes which is suitable for modelling hysteresis loops and finding remanent states in the PSD regime. Preliminary results suggest the more rigorously defined micromagnetic models exhibit higher coercivities and extended single domain ranges when compared to more simplistic approaches.

  4. The universality of enzymatic rate-temperature dependency.

    Science.gov (United States)

    Elias, Mikael; Wieczorek, Grzegorz; Rosenne, Shaked; Tawfik, Dan S

    2014-01-01

    Organismal adaptation to extreme temperatures yields enzymes with distinct configurational stabilities, including thermophilic and psychrophilic enzymes, which are adapted to high and low temperatures, respectively. These enzymes are widely assumed to also have unique rate-temperature dependencies. Thermophilic enzymes, for example, are considered optimal at high temperatures and effectively inactive at low temperatures due to excess rigidity. Surveying published data, we find that thermophilic, mesophilic, and psychrophilic enzymes exhibit indistinguishable rate-temperature dependencies. Furthermore, given the nonenzymatic rate-temperature dependency, all enzymes, regardless of their operation temperatures, become >10-fold less powerful catalysts per 25 °C temperature increase. Among other factors, this loss of rate acceleration may be ascribed to thermally induced vibrations compromising the active-site catalytic configuration, suggesting that many enzymes are in fact insufficiently rigid.

  5. Temperature Impacts on Deep-Sea Biodiversity

    Science.gov (United States)

    Yasuhara, M.; Danovaro, R.

    2015-12-01

    Temperature is considered to be a fundamental factor controlling biodiversity in marine ecosystems, but precisely what role temperature plays in modulating diversity is still not clear. The deep ocean, lacking light and in situ photosynthetic primary production, is an ideal model system to test the effects of temperature changes on biodiversity. Here we synthesize current knowledge on temperature-diversity relationships in the deep sea. Our results from both present and past deep-sea assemblages suggest that, when a wide range of deep-sea bottom-water temperatures is considered, a unimodal relationship exists between temperature and diversity (that may be right skewed). It is possible that temperature is important only when at relatively high and low levels but does not play a major role in the intermediate temperature range. Possible mechanisms explaining the temperature-biodiversity relationship include the physiological-tolerance hypothesis, the metabolic hypothesis, island biogeography theory, or some combination of these. The possible unimodal relationship discussed here may allow us to identify tipping points at which on-going global change and deep-water warming may increase or decrease deep-sea biodiversity. Predicted changes in deep-sea temperatures due to human-induced climate change may have more adverse consequences than expected considering the sensitivity of deep-sea ecosystems to temperature changes.

  6. Temperature impacts on deep-sea biodiversity.

    Science.gov (United States)

    Yasuhara, Moriaki; Danovaro, Roberto

    2016-05-01

    Temperature is considered to be a fundamental factor controlling biodiversity in marine ecosystems, but precisely what role temperature plays in modulating diversity is still not clear. The deep ocean, lacking light and in situ photosynthetic primary production, is an ideal model system to test the effects of temperature changes on biodiversity. Here we synthesize current knowledge on temperature-diversity relationships in the deep sea. Our results from both present and past deep-sea assemblages suggest that, when a wide range of deep-sea bottom-water temperatures is considered, a unimodal relationship exists between temperature and diversity (that may be right skewed). It is possible that temperature is important only when at relatively high and low levels but does not play a major role in the intermediate temperature range. Possible mechanisms explaining the temperature-biodiversity relationship include the physiological-tolerance hypothesis, the metabolic hypothesis, island biogeography theory, or some combination of these. The possible unimodal relationship discussed here may allow us to identify tipping points at which on-going global change and deep-water warming may increase or decrease deep-sea biodiversity. Predicted changes in deep-sea temperatures due to human-induced climate change may have more adverse consequences than expected considering the sensitivity of deep-sea ecosystems to temperature changes.

  7. . and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include V factor-dependent and V factor-independent isolates, Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nvo., comb. nov., Aggregatibacter aphrophilus comb. nov

    DEFF Research Database (Denmark)

    Nørskov-Lauritsen, N.; Kilian, Mogens

    2006-01-01

    The aim of this study was to reinvestigate the relationships and the generic affiliations of the species Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis. The nicotinamide phosphoribosyltransferase gene (nadV) conferring V factor-ind......)=NCTC 5906(T)) and Aggregatibacter segnis comb. nov. (type strain HK316(T)=ATCC 33393(T)=CCUG 10787(T)=CCUG 12838(T)=CIP 103292(T)=NCTC 10977(T)). The species of the genus Aggregatibacter are independent of X factor and variably dependent on V factor for growth in vitro......The aim of this study was to reinvestigate the relationships and the generic affiliations of the species Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis. The nicotinamide phosphoribosyltransferase gene (nadV) conferring V factor......-independent growth was identified in Haemophilus aphrophilus. The gene encodes a polypeptide of 462 amino acids that shows 74.5 % amino acid sequence identity to the corresponding enzyme from Actinobacillus actinomycetemcomitans. Ten isolates of Haemophilus paraphrophilus all carried a nadV pseudogene. DNA from...

  8. Factors influencing 14C concentrations of algal and archaeal lipids and their associated sea surface temperature proxies in the Black Sea

    Science.gov (United States)

    Kusch, Stephanie; Rethemeyer, Janet; Hopmans, Ellen C.; Wacker, Lukas; Mollenhauer, Gesine

    2016-09-01

    Understanding the preservation and deposition history of organic molecules is crucial for the understanding of paleoenvironmental information contained in their abundance ratios such as Uk‧37 and TEX86 used as proxies for sea surface temperature (SST). Based on their relatively high refractivity, alkenones and glycerol dialkyl glycerol tetraethers (GDGTs) can survive postdepositional processes like lateral transport, potentially causing inferred SSTs to be misleading. Likewise, selective preservation of alkenones and GDGTs may cause biases of the SST proxies themselves and can lead to decoupling of both proxy records. Here we report compound-specific radiocarbon data of marine biomarkers including alkenones, GDGTs, and low molecular weight (LMW) n-fatty acids from Black Sea sediments deposited under different redox regimes to evaluate the potentially differential preservation of both biomarker classes and its effect on the SST indices Uk‧37 and TEX86. The decadal Δ14C values of alkenones, GDGTs, and LMW n-fatty acids indicate similar preservation under oxic, suboxic, and anoxic redox regimes and no contribution of pre-aged compounds, e.g., by lateral supply. Moreover, similar 14C concentrations of crenarchaeol, alkenones, and LMW n-fatty acids imply that the thaumarchaeotal GDGTs preserved in these sediments are produced in the euphotic zone rather than in subsurface/thermocline waters. However, we observe biomarker-based SSTs that strongly deviate (ΔSST up to 8.4 °C) from in situ measured mean annual SSTs in the Black Sea. This is not due to redox-dependent differential biomarker preservation as implied by their Δ14C values and spatial SST pattern. Since contributions from different sources can largely be excluded, the deviation of the Uk‧37 and TEX86 proxy-derived SSTs from in situ SSTs requires further study of phylogenetic and other yet unknown environmental controls on alkenone and GDGT lipid distributions in the Black Sea.

  9. Progress in advanced high temperature turbine materials, coatings, and technology

    Science.gov (United States)

    Freche, J. C.; Ault, G. M.

    1978-01-01

    Advanced materials, coatings, and cooling technology is assessed in terms of improved aircraft turbine engine performance. High cycle operating temperatures, lighter structural components, and adequate resistance to the various environmental factors associated with aircraft gas turbine engines are among the factors considered. Emphasis is placed on progress in development of high temperature materials for coating protection against oxidation, hot corrosion and erosion, and in turbine cooling technology. Specific topics discussed include metal matrix composites, superalloys, directionally solidified eutectics, and ceramics.

  10. Temperature as an ecological factor in the distribution of two closely related freshwater Triclads: an experimental study. [Polycelis tenuis, polycelis nigra

    Energy Technology Data Exchange (ETDEWEB)

    Lascombe, C.; Pattee, E.; Bornard, C.

    1975-01-01

    The influence of temperature on the ecophysiology of two closely related limnophilic Triclads, Polycelis tenuis and P. nigra, in the Lyons region was investigated. Both species have the same physiological rate in the middle zone of the temperature range, but P. tenuis prevails at both ends of the range. It tolerates higher temperatures and its reproduction rate is greater in the cold. Also, because of the existence of physiological races, it seems adapted to a greater diversity of situations. It appears as a real eurytherm. These different points contribute to the explanation of the habitat of both species in the region.

  11. CLIMATOLOGICAL DIAGNOSIS OF WINTER TEMPERATURE VARIATIONS IN GUANGDONG

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Using the monthly mean and minimum temperature data of the 36 observation stations in Guangdong, the climatological features of the temperatures have been analyzed, including characteristics of trends, abrupt changes and periods. And the possible affecting factors on the winter warming in Guangdong have been discussed. The results show that the winter temperatures, particularly the monthly mean minimum temperatures in Guangdong, have a warming trend. The rise of the winter minimum temperatures in Guangdong began in the second half of 1960's and the warming was more evident since the 1980's.

  12. 温度降水等气候因子变化对中国玉米产量的影响%Effect of climatic factors such as temperature, precipitation on maize production in China

    Institute of Scientific and Technical Information of China (English)

    王柳; 熊伟; 温小乐; 冯灵芝

    2014-01-01

    . Information about the climatic risks posed on crop growth, and yield responses to the specific climatic risks is prerequisite for understanding the underlying mechanisms of climate change impacts and devising appropriate adaptation strategies. This study first identified the changes of growing-season climatic variables (temperature, precipitation, and solar radiation) from 1982-2006 for China’s maize production. Using the relationships between changes in survey maize yield and climatic variables and their spatial variations, we investigated and untangled the impacts of different climatic variables on maize yield. Our analysis demonstrated that the growing-season temperatures, including daily maximum, minimum and mean temperatures, exhibited significant increase during 1981-2006, indicating the potential climatic risks for maize growth in China. Growing-season diurnal temperature range, precipitation and solar radiation also exhibited detectable changes, but limited to small parts of the maize area. During 1981-2006, there were significant negative correlations between national maize yield and temperatures (include mean, maximum, and minimum temperatures). Maize yield in some maize areas also exhibited linear correlation relationship to growing-season diurnal temperature range, solar radiation, and precipitation. With a 1℃ warming in growing-season temperature, 1℃ increase in diurnal temperature range, a 10% decrease in radiation and precipitation, much of the maize area showed detectable yield response to these changes. Maize experienced depressed yield to the 1℃ warming in growing-season temperature, denoting by roughly a quarter of China’s maize area exhibiting depressed yield and an estimated reduction of 25.1%across the regions that have detectable negative yield responses. The four climatic variables have diverse impacts on the maize yield in terms of the magnitude of yield change and the spatial variation of yield response. We identified the key climatic

  13. Temperature seems to be an important factor when assessing effects of a glyphosate-based herbicide on egg and tadpole growth of Common toads (Bufo bufo; Amphibia L.

    Directory of Open Access Journals (Sweden)

    Fabian Baier

    2016-08-01

    Full Text Available Glyphosate-based herbicide formulations are broadly used in agriculture, silviculture, horticulture as well as in private gardens all over the world, thus posing the risk of potential contamination of nearby aquatic bodies inhabited by amphibians. Concurrently, climate change can be expected to alter the temperature of amphibian breeding sites. However, while either glyphosate-based herbicides or temperature have been shown to separately affect the development of amphibians, very little is known on possible interactive effects. We studied the impact of herbicide concentrations and temperature on growth and development of eggs and tadpoles of the Common toad (Bufo bufo L.. We hypothesized that (i eggs would be better protected against herbicides than tadpoles because of their jelly coating, (ii that higher temperatures would reduce potential herbicide effects because of an accelerated growth and a lower sensitivity of larger specimens. We conducted one experiment starting with eggs (Gosner stage, GS 9 and another experiment starting with tadpoles (GS 21-24 using a full factorial design with 5 concentrations of the herbicide formulation Roundup® LB Plus (0 mg acid equivalent L-1, 0.5 mg a.e. L-1, 1.0 mg a.e. L-1 or 1.5 mg a.e. L-1 and a pulse treatment with 3-4 times addition of 0.5 a.e. mg L-1 over the course of several weeks and two temperature levels (15°C and 20°C. Contrary to our expectation, our results showed that toad eggs are more sensitive to herbicides than tadpoles leading to an averaged 31% increase in total length, tail length and body length compared to the herbicide-free control. Tadpole morphology, development or mortality was not influenced by herbicides. Higher temperature accelerated growth of both eggs and tadpoles. This is among the first study showing interactive effects between herbicides and temperature especially for egg development resulting in more pronounced herbicide effects at lower temperatures than at higher

  14. Numerical Analysis of Mold Deformation Including Plastic Melt Flow During Injection Molding

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Joon Tae; Lee, Bong-Kee [Chonnam National University, Gwangju (Korea, Republic of)

    2014-07-15

    In the present study, a numerical analysis of an injection molding process was conducted for predicting the mold deformation considering non-Newtonian flow, heat transfer, and structural behavior. The accurate prediction of mold deformation during the filling stage is important to successfully design and manufacture a precision injection mold. While the local mold deformation can be caused by various factors, a pressure induced by the polymer melt is considered to be one of the most significant ones. In this regard, the numerical simulation considering both the melt filling and the mold deformation was carried out. A mold core for a 2D axisymmetric center-gated disk was used for the demonstration of the present study. The flow behavior inside the mold cavity and temperature distribution were analyzed along with the core displacement. Also, a Taguchi method was employed to investigate the influence of the relevant parameters including flow velocity, mold core temperature, and melt temperature.

  15. Carbon dioxide evolution and temperature factors in early growth of plastic mulched plants. [Cucumis melo L. var. reticulatus; Lactuca sativa L. var. crispa

    Energy Technology Data Exchange (ETDEWEB)

    Betts, C.; Ruf, R.H. Jr.

    1966-01-01

    Cantaloupe (Cucumis melo L. var. reticulatus) and lettuce (Lactuca sativa L. var. crispa) were grown in the greenhouse in redwood boxes with bare and plastic mulched soil. Soil temperature in the bare boxes was equated to the plastic mulch with buried temperature coils. Bottled CO/sub 2/ was used to bring the concentration around the plants in bare soil up to the concentration around mulched plants. Carbon dioxide was sampled in leaf canopy. The temperature treatment increased the yields of the bare soil so that they were comparable to those of the plastic mulched soil. Yields from the soil with the auxiliary CO/sub 2/ were lower than those of the mulched treatment.

  16. [Phosphoethanolamine in the brain of the eurythermal pond fish Perccottus glehni (Eleotridae, Perciformes, Dyb. 1877) as a phenomenon depending on temperature factor].

    Science.gov (United States)

    Karanova, M V

    2013-01-01

    Effects of a seasonal decrease of environmental temperature and cold shock on pools of free amino acids (FAA) was studied in brain of the eurythermal pond fish P. glehni. It is for the first time that in the brain of eurythermal animals the nonprotein amino acid phosphoethanolamine (PEA) was revealed. It was found there in a large amount only under conditions of near-zero temperatures. It was shown that in the P. glehni brain, as a result of the seasonal decrease of temperature, the PEA pool rose intensively from 0.3 % at the summer period to 33.6 % in winter. On the contrary, the brain taurine pool that in the summer was the highest as compared with other FAA (29.0% of the total pool) decreased to 8.9% by the beginning of the winter period. The same negative correlation of the taurine and PEA amounts was found under action of acute cold shock (+1 degree C): throughout 4 days the taurine level also decreased from 32.2 to 14.5% of the total pool, whereas the PEA level rose swiftly (from 2.1 to 15.3%). Both kinds of the low temperature action led, apart from PEA, to an intensive increase of the serine pool and accumulation of phosphoserine. Role of PEA in biochemical evolution and adaptation of brain to low temperatures is discussed. It is suggested that accumulation of PEA, phosphoserine, and serine is associated with a change of the status of phospholipids of membrane at low temperatures.

  17. Relationship between High Yield in Cone Production for Pinus sy lvest ris var .mongolica and Temperature Factor%温度因子与樟子松球果产量丰产的关系

    Institute of Scientific and Technical Information of China (English)

    柴汝松; 侯庆娟

    2014-01-01

    为了分析温度因子与樟子松(Pinus sylvestnis var .mongolica Litv .)球果产量丰歉产之间的关系,设置3块面积为150 m×300 m的样带,连续6年对样带内单株樟子松的结实量和月平均温度进行调查,结合以上数据,逐年进行处理,采用因子筛选法和线性回归分析,进行温度因子与樟子松球果产量的相关系数分析。结果表明:球果生长期第3年3月份月均温、第2年11月的极端最高温度与樟子松球果产量之间的相关系数颇高,回归关系显著。%In order to analyze the relationship among temperature factor ,high yield and low yield in cone production for Pinus sylvestris var .mongolica ,three sample plots were set in the study area ;the cone production and the monthly mean temperature were investigated for six consecutive years ;combining the above data ,analyzed year by year;correlation coefficient analysis be-tween temperature factor & yield of cones were conducted by using factor screening method & linear regression analysis .Re-sult shows that :the correlation coefficient among the monthly mean temperature in March in the 3rd year of cone growing stage ,extreme temperature in November in the 2nd year ,the yield among the cone production of Pinus sylvestris var .mongol-ica is quite high and its regression relationship is significant .

  18. The relationship between body and ambient temperature and corneal temperature

    DEFF Research Database (Denmark)

    Kessel, Line; Johnson, Leif; Arvidsson, Henrik Sven

    2010-01-01

    Exposure to elevated ambient temperatures has been mentioned as a risk factor for common eye diseases, primarily presbyopia and cataract. The aim of the present study was to examine the relationship among ambient, cornea, and body core temperature.......Exposure to elevated ambient temperatures has been mentioned as a risk factor for common eye diseases, primarily presbyopia and cataract. The aim of the present study was to examine the relationship among ambient, cornea, and body core temperature....

  19. The relationship between body and ambient temperature and corneal temperature

    DEFF Research Database (Denmark)

    Kessel, Line; Johnson, Leif; Arvidsson, Henrik Sven

    2010-01-01

    Exposure to elevated ambient temperatures has been mentioned as a risk factor for common eye diseases, primarily presbyopia and cataract. The aim of the present study was to examine the relationship among ambient, cornea, and body core temperature.......Exposure to elevated ambient temperatures has been mentioned as a risk factor for common eye diseases, primarily presbyopia and cataract. The aim of the present study was to examine the relationship among ambient, cornea, and body core temperature....

  20. Next-generation transcriptome profiling reveals insights into genetic factors contributing to growth differences and temperature adaptation in Australian populations of barramundi (Lates calcarifer).

    Science.gov (United States)

    Newton, James R; Zenger, Kyall R; Jerry, Dean R

    2013-09-01

    Identification of genetically-regulated adaptation in fish is a precursor to understanding how populations will respond to future climate induced stressors like temperature. Australian populations of barramundi (Lates calcarifer) show strong evidence of local adaptation to temperature. However, the phenotypic consequences of this adaptation are unknown and the genetic mechanisms underlying this response are poorly understood. In the current study, two populations of barramundi from temperature extremes of the species Australian distribution were communally reared at cool (22°C), control (28°C) and hot (36°C) water temperatures for 3.5months. Southern populations of barramundi originating from a cooler environment grew significantly faster at 22°C than northern populations of warm adapted barramundi. However, no difference in population growth was present at either 28°C or 36°C. The underlying transcriptome profile of barramundi was examined via Illumina mRNA deep sequencing to determine the major contributing gene categories giving rise to phenotypic differences in barramundi population growth. Gene ontology (GO) analysis revealed enrichment in categories relating to the regulation of peptidase activity as well as microtubule, cytoplasmic and cellular metabolic based processes. Further analysis of the GO category "microtubule based process" with associated genes from the "response to stress" category revealed an apparent re-organization of cytoskeletal elements in response to an induced cold stress in northern barramundi reared at 22°C, when compared with northern barramundi reared at 36°C. Between southern barramundi and northern barramundi reared at 36°C, an analysis of the "endopeptidase inhibitor activity" GO category in conjunction with stress genes indicated a suppression of the complement system in southern barramundi along with an increase in the cellular stress response. The results of the present study show that southern populations of barramundi

  1. Simulation and experiment on influence factor of contact high temperature strain measurement accuracy%高温应变接触式测量精度影响因素研究

    Institute of Scientific and Technical Information of China (English)

    王文瑞; 张佳明; 聂帅

    2015-01-01

    The research of thermal strength and fatigue of high temperature structure needs high temperature strain measure⁃ment. The influence factor of high temperature strain was studied on the basis of independently developed high temperature free frame wire strain gauges. The strain transmission and distribution model was established according to the structure and measuring principle of high temperature strain gauge. The influence of size parameters and using parameters on strain measurement accuracy was obtained by the comparison between the strain fields of tested structure and sensitive gate, which provides the basis of design and utilization of strain gauge. The proper structural parameters were proposed in this paper which is verified by the high tempera⁃ture strain measuring experiment. The precision influence factor of contact high temperature strain measurement was determined to lower the factor sensitivity and improve the precision of high temperature strain measurement, which provides a basis to perform measuring precision research of other forms of strain gauges.%高温结构热强度、热疲劳等问题的研究需要高温应变的精准测量。利用自主研制的自由框架丝栅式高温应变片开展结构高温应变测量精度影响因素研究,结合应变片结构与测量原理,建立高温应变片应变信息传递以及分布有限元模型,分析对比被测构件与敏感栅丝表面应变场的分布情况,确定高温应变片尺寸参数与使用参数对应变测量精度的影响因素,为应变片的设计与使用提供依据。提出了合适的丝栅式应变片结构参数,并利用高温应变片实验进行验证,确定了高温接触式应变测量精度影响因素,降低环节敏感性,提高高温应变测量精度,并可为其他形式的应变片的测量精度研究提供依据。

  2. Models of bovine babesiosis including juvenile cattle.

    Science.gov (United States)

    Saad-Roy, C M; Shuai, Zhisheng; van den Driessche, P

    2015-03-01

    Bovine Babesiosis in cattle is caused by the transmission of protozoa of Babesia spp. by ticks as vectors. Juvenile cattle (Babesiosis, rarely show symptoms, and acquire immunity upon recovery. Susceptibility to the disease varies between breeds of cattle. Models of the dynamics of Bovine Babesiosis transmitted by the cattle tick that include these factors are formulated as systems of ordinary differential equations. Basic reproduction numbers are calculated, and it is proved that if these numbers are below the threshold value of one, then Bovine Babesiosis dies out. However, above the threshold number of one, the disease may approach an endemic state. In this case, control measures are suggested by determining target reproduction numbers. The percentage of a particular population (for example, the adult bovine population) needed to be controlled to eradicate the disease is evaluated numerically using Columbia data from the literature.

  3. Full Boltzmann equations for leptogenesis including scattering

    CERN Document Server

    Hahn-Woernle, F; Wong, Y Y Y

    2009-01-01

    We study the evolution of a cosmological baryon asymmetry produced via leptogenesis by means of the full classical Boltzmann equations, without the assumption of kinetic equilibrium and including all quantum statistical factors. Beginning with the full mode equations we derive the usual equations of motion for the right-handed neutrino number density and integrated lepton asymmetry, and show explicitly the impact of each assumption on these quantities. For the first time, we investigate also the effects of scattering of the right-handed neutrino with the top quark to leading order in the Yukawa couplings by means of the full Boltzmann equations. We find that in our full Boltzmann treatment the final lepton asymmetry can be suppressed by as much as a factor of 1.5 in the weak wash-out regime (K1), the full Boltzmann treatment and the integrated approach give nearly identical final lepton asymmetries (within 10 % of each other at K>3). Finally, we show that the opposing effects of quantum statistics on decays/i...

  4. Enhanced temperature stability and quality factor with Hf substitution for Sn and MnO2 doping of (Ba0.97Ca0.03)(Ti0.96Sn0.04)O3 lead-free piezoelectric ceramics with high Curie temperature

    Science.gov (United States)

    Tsai, Cheng-Che; Chao, Wei-Hsiang; Chu, Sheng-Yuan; Hong, Cheng-Shong; Weng, Chung-Ming; Su, Hsiu-Hsien

    2016-12-01

    In this work, the process of two-stage modifications for (Ba0.97Ca0.03)(Ti0.96Sn0.04-xHfx)O3 (BCTS4-100xH100x) ceramics was studied. The trade-off composition was obtained by Hf substitution for Sn and MnO2 doping (two-stage modification) which improves the temperature stability and piezoelectric properties. The phase structure ratio, microstructure, and dielectric, piezoelectric, ferroelectric, and temperature stability properties were systematically investigated. Results showed that BCTS4-100xH100x piezoelectric ceramics with x=0.035 had a relatively high Curie temperature (TC) of about 112 °C, a piezoelectric charge constant (d33) of 313 pC/N, an electromechanical coupling factor (kp) of 0.49, a mechanical quality factor (Qm) of 122, and a remnant polarization (Pr) of 19 μ C /cm2 . In addition, the temperature stability of the resonant frequency (fr), kp, and aging d33 could be tuned via Hf content. Good piezoelectric temperature stability (up to 110 °C) was found with x =0.035. BCTS0.5H3.5 + a mol% Mn (BCTSH + a Mn) piezoelectric ceramics with a = 2 had a high TC of about 123 °C, kp ˜ 0.39, d33 ˜ 230 pC/N, Qm ˜ 341, and high temperature stability due to the produced oxygen vacancies. This mechanism can be depicted using the complex impedance analysis associated with a valence compensation model on electric properties. Two-stage modification for lead-free (Ba0.97Ca0.03)(Ti0.96Sn0.04)O3 ceramics suitably adjusts the compositions for applications in piezoelectric motors and actuators.

  5. Enhanced temperature stability and quality factor with Hf substitution for Sn and MnO2 doping of (Ba0.97Ca0.03(Ti0.96Sn0.04O3 lead-free piezoelectric ceramics with high Curie temperature

    Directory of Open Access Journals (Sweden)

    Cheng-Che Tsai

    2016-12-01

    Full Text Available In this work, the process of two-stage modifications for (Ba0.97Ca0.03(Ti0.96Sn0.04-xHfxO3 (BCTS4-100xH100x ceramics was studied. The trade-off composition was obtained by Hf substitution for Sn and MnO2 doping (two-stage modification which improves the temperature stability and piezoelectric properties. The phase structure ratio, microstructure, and dielectric, piezoelectric, ferroelectric, and temperature stability properties were systematically investigated. Results showed that BCTS4-100xH100x piezoelectric ceramics with x=0.035 had a relatively high Curie temperature (TC of about 112 °C, a piezoelectric charge constant (d33 of 313 pC/N, an electromechanical coupling factor (kp of 0.49, a mechanical quality factor (Qm of 122, and a remnant polarization (Pr of 19μC/cm2. In addition, the temperature stability of the resonant frequency (fr, kp, and aging d33 could be tuned via Hf content. Good piezoelectric temperature stability (up to 110 °C was found with x =0.035. BCTS0.5H3.5 + a mol% Mn (BCTSH + a Mn piezoelectric ceramics with a = 2 had a high TC of about 123 °C, kp ∼ 0.39, d33 ∼ 230 pC/N, Qm ∼ 341, and high temperature stability due to the produced oxygen vacancies. This mechanism can be depicted using the complex impedance analysis associated with a valence compensation model on electric properties. Two-stage modification for lead-free (Ba0.97Ca0.03(Ti0.96Sn0.04O3 ceramics suitably adjusts the compositions for applications in piezoelectric motors and actuators.

  6. The study of temperature changes around metal in ultrashort wave electric-field and it's influence factors%超短波电场对金属周围升温变化的影响

    Institute of Scientific and Technical Information of China (English)

    梁维娣; 张志强; 孙师; 田丽君

    2011-01-01

    目的 探讨超短波电场对金属周围升温变化的影响因素.方法 采用医用超短波治疗仪1档,调谐,输出80 mA,取0.2 ml水作为载体,金属物一端深入水中,改变金属物长度、金属物与电极板间垂直距离、金属物在电磁场中的摆放位置以及超短波的作用时间,采用数字电偶温度表测量不同治疗条件前、后水温的变化.结果 相同条件下,金属线长轴平行于电极板,金属物场外实际长度为10 cm、20 cm、30 cm、50 cm、70 cm、90 cm时,其周围升温分别为4.37℃、8.30℃、18.00℃、20.64℃、32.92℃、38.96℃;金属物长轴平行于电极板,金属线与一侧电极板间垂直间距分别为1.5 cm、3.0 cm、4.5 cm、6.0 cm时,金属周围升温分别为66.03℃、49.37℃、14.80℃、0.87℃;如果金属物长轴垂直于电极板,金属一端与极板间距离为5 cm、9 cm、15 cm时,金属周围升温分别为56.10℃、26.64℃、11.07℃;金属与电场边缘的垂直间距为0 cm、5 cm、10 cm、15 cm时,金属周围升温分别为25.32℃、10.26℃、2.88℃、1.53℃;固定长度的金属物,涵盖入电场内的实际长度分别为20 cm、10 cm、0 cm时,金属周围升温分别为2.84℃、4.04℃、7.30℃;同等条件下,改变超短波作用时间为5 min、10 min时,金属周围升温分别为24.90℃、39.07℃.结论 当金属物长轴平行置于电极板正中间位置,且金属完全置于电场内并远离极板边缘时,通过减短金属物的长度、两极板间的距离以及超短波的作用时间,可降低金属物周围的升温幅度.%Objective To study the temperature changes around metal in ultrashort wave electric-field and it's influence factors.Methods Medical ultrashort wave therapeutic instrument was used and output switen was set at the 1 st grade.After tuning, one end of metal object was placed into 0.2ml water contained in a plastic tube ( with a length of 2cm and diameter of 2mm).Temperature changes of water around

  7. Perioperative thermoregulation and temperature monitoring.

    Science.gov (United States)

    Insler, Steven R; Sessler, Daniel I

    2006-12-01

    Traditionally, hypothermia has been thought of and used perioperatively as a presumptive strategy to reduce cerebral and myocardial tissue sensitivity to ischemia. Evidence, however, is mounting that maintenance of perioperative normothermia is associated with improved outcomes in patients undergoing all types of surgery, even cardiac surgery. Ambient environmental temperature is sensed by free nerve endings in the dermal and epidermal layers of the skin, which are the axonal extensions of thermosensitive neurons found in the dorsal root ganglia. Free nerve endings in the skin, by means of transient receptor ion channels that are specifically thermosensitive, also may directly sense environmental temperature. This information is transmitted to the preoptic/anterior hypothalamic region of the brainstem, which coordinates efferent responses to abnormal temperature deviation. People have evolved a highly integrated thermoregulatory system that maintains core body temperature in a relatively narrow temperature range. This system, though, is impaired by the stress of regional and general anesthesia, and the added exposure that occurs during the surgical procedure. When combined, these factors can lead to unwanted thermal disturbances. In a cold operating room environment, hypothermia is the usual perioperative consequence; however, hyperthermia is more dangerous and demands immediate diagnosis. Intraoperative hypothermia usually develops in three phases. The first is a rapid decrease in core temperature following anesthetic induction, which mostly results from redistribution of heat from the core thermal compartment to the outer shell of the body. This is followed by a slower, linear reduction in the core temperature that may last several hours. Finally, a core temperature plateau is reached, after which core temperature remains virtually unchanged for the remainder of the procedure. The plateau can be passive or result from re-emergence of thermoregulatory control in

  8. Temperature monitored control system for high-frequency welded pipe and analysis of its influencing factors%高频焊管温度监控系统及其影响因素分析

    Institute of Scientific and Technical Information of China (English)

    何世权; 徐德怀; 樊丁; 徐德茹; 田禾

    2011-01-01

    针对高频焊管生产测量环境恶劣以及依靠经验观察来控制焊接温度的特点,提出高频焊管温度监控系统.该系统利用抗干扰强、测量精度高的比色测温仪采集焊接温度,通过LabVIEW控制高频电源的输出功率,实现温度调整,通过PID控制实现闭环控制.实验证明,监控系统能够准确检测高频焊管的焊接温度,并有效地提高温度的稳定性.最后提出影响高频焊管温度监控系统的因素.%Aimed at the poor measurement and production environment and dependence on empirical observation and control of welding temperature in the production of high-frequency welded pipe, a high-frequency welded pipe temperature monitored control system was proposed. In this system, a colorimetric pyrometer with strong anti-jamming and high measurement precision was used. By using software IabVIEW, the high-frequency power output was controlled to achieve temperature adjustment and closed-loop control. It was verified by test that the system could accurately detect the high-frequency welded pipe temperature, and effectively improve the temperature stability. Finally, the factors that influence the monitore control system of temperature of high-frequency welded pipe were suggested.

  9. Analysis of the factors of toner low - temperature fusing performance%墨粉低温定影性能的影响因素分析

    Institute of Scientific and Technical Information of China (English)

    姜真; 冯华栋; 涂海平; 刁运佳

    2011-01-01

    The toner composition for copiers and printers and the fusing performance evaluation methods were introduced.The effects of different molecular weight distribution polystyrene resin,polyester resin,low molecular weight wax on the toner fusing performance were investigated.The results showed that adding low molecular weight and high molecular weight polystyrene acrylic resin in the toner resin component could reduce the toner fusing temperature,expand the fusing temperature range and improve the fixing performance.The low molecular weight polyester resins better adapted to low temperature fusing requirements and provide a good snapshot durability and preservation.The use of low molecular weight wax would help to improve the offset performance.%介绍了复印机、打印机墨粉的组成及其定影性能评价方法,探讨了不同分子质量分布的聚苯乙烯树脂、聚酯树脂、低分子蜡对墨粉定影性能的影响。结果表明,在墨粉树脂组分中同时加入低分子质量组分和高分子质量组分的聚苯乙烯丙烯酸树脂可降低墨粉的定影温度、扩大定影温度范围并改善定影性能;低分子质量聚酯树脂更适应低温定影要求并提供良好的耐久性和保存性;低分子蜡的使用有利于改善offset性能。

  10. 径向式热管与重力式热管管壁温度的影响因素分析%ANALYSIS ON THE INFLUENCING FACTORS OF TUBE WALL TEMPERATURE ON RADIAL AND GRAVITATIONAL HEAT PIPE

    Institute of Scientific and Technical Information of China (English)

    邵帅; 冯洪庆; 杨肖曦; 汪欣; 朱炳

    2013-01-01

    阐述了热管进行锅炉烟气余热回收时,管壁温度的控制对于防止低温腐蚀的必要性,文章计算分析了管径、翅片长度、翅片厚度、翅片间距、冷流体入口温度等因素对于管壁温度的影响规律.分析认为增加热管管径、减小翅片间距,可以适当提高壁温.%This paper stresses on the necessity of pipe wall temperature control to prevent low temperature corrosion. It calculates and analyzes the influence of the factors such as tube diameter, fin length,fin thickness,fin space and inlet temperature of cold fluid on pipe wall. The tube diameter of the heat pipe is increased, the fin space is reduced and the wall temperature is increased properly. It provides reference for the field application.

  11. Solubilization of immune complexes in complement factor deficient sera and the influence of temperature, ionic strength and divalent cations on the solubilization reaction

    DEFF Research Database (Denmark)

    Baatrup, Gunnar; Petersen, Ivan; Svehag, Svend-Erik;

    1984-01-01

    The complement-mediated solubilization (CMS) of immune complexes (IC) and the initial kinetics (IKS) of this reaction in human sera depleted of or deficient in C2, C3, C8, factors B, P and I were investigated. Sera depleted of B or P and those lacking native C3 or factor I showed virtually no CMS...... by a radioassay and kinetic data for the binding of C3b to preformed immune complexes. The CMS capacity reached maximum at 39-41 degrees C and at an ionic strength of approximately 0.20 mu. Selective chelation of Mg2+ completely abolished the CMS of IC. Maximal CMS was observed at Mg2+ concentration of about 2m...

  12. Research on Low-temperature Thermal Radiation Influencing Factors Based on PASCO System%基于PASCO系统的低温热辐射影响因素的研究

    Institute of Scientific and Technical Information of China (English)

    陈新; 陈龙; 李宇飞; 王珊

    2014-01-01

    Low-temperature thermal radiation influencing factors such as heated cube surface,temperature,dis-tance,relative location were studied by using the PASCO system. The results were shown visually with the data cloud pictures and three-dimensional maps by using a series of comparison experiments.%利用美国PASCO公司传感器热辐射实验系统对加热的立方腔体的表面特性、温度、距离、相对位置等主要影响因素对低温热辐射实验的影响进行了对比研究,并将实验结果以数据云图和3D立体图的形式直观的显示出来。

  13. Room temperature creep in metals and alloys

    Energy Technology Data Exchange (ETDEWEB)

    Deibler, Lisa Anne [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Materials Characterization and Performance

    2014-09-01

    Time dependent deformation in the form of creep and stress relaxation is not often considered a factor when designing structural alloy parts for use at room temperature. However, creep and stress relaxation do occur at room temperature (0.09-0.21 Tm for alloys in this report) in structural alloys. This report will summarize the available literature on room temperature creep, present creep data collected on various structural alloys, and finally compare the acquired data to equations used in the literature to model creep behavior. Based on evidence from the literature and fitting of various equations, the mechanism which causes room temperature creep is found to include dislocation generation as well as exhaustion.

  14. Development of a predictive model for Salmonella spp. reduction in meat jerky product with temperature, potassium sorbate, pH, and water activity as controlling factors.

    Science.gov (United States)

    Juneja, Vijay K; Valenzuela-Melendres, Martin; Heperkan, Dilek; Bautista, Derrick; Anderson, David; Hwang, Cheng-An; Peña-Ramos, Aida; Camou, Juan Pedro; Torrentera-Olivera, Noemi

    2016-11-07

    The objective of this study was to develop a predictive model for the inactivation of Salmonella spp. in ground beef jerky as a function of temperature (T), pH, potassium sorbate (PS), and final water activity (aw). Following a central composite design, ground beef was combined with PS (0 to 0.3%, w/w), pH adjusted from 5 to 7, inoculated with a cocktail of 6 serotypes of Salmonella spp. and heat processed at temperatures between 65 and 85°C until the final aw ranging from 0.65 to 0.85 was achieved. Surviving Salmonella cells were enumerated on tryptic soy agar overlaid with xylose lysine deoxycholate agar (pre-tempered to 47°C) after incubation for 48h at 30°C. Bacterial inactivation was quantified in terms of logarithmic reductions of Salmonella counts (log10CFU/g) and inactivation rate (log10(CFU/g)/h). The results indicated that pH, PS and T significantly (pSalmonella in beef jerky. Decreasing meat pH significantly (pSalmonella spp. Beef jerky processed at 82°C, pH5.5, with 0.25% PS to a final aw of 0.7 resulted in a maximum Salmonella logarithmic reduction of 5.0log10CFU/g and an inactivation rate of 1.3log10(CFU/g)/h. The predictive model developed can be used to effectively design drying processes for beef jerky under low humidity conditions and thereby, ensuring an adequate degree of protection against risks associated with Salmonella spp.

  15. Biophysical control of leaf temperature

    Science.gov (United States)

    Dong, N.; Prentice, I. C.; Wright, I. J.

    2014-12-01

    In principle sunlit leaves can maintain their temperatures within a narrower range than ambient temperatures. This is an important and long-known (but now overlooked) prediction of energy balance theory. Net radiation at leaf surface in steady state (which is reached rapidly) must be equal to the combination of sensible and latent heat exchanges with surrounding air, the former being proportional to leaf-to-air temperature difference (ΔT), the latter to the transpiration rate. We present field measurements of ΔT which confirm the existence of a 'crossover temperature' in the 25-30˚C range for species in a tropical savanna and a tropical rainforest environment. This finding is consistent with a simple representation of transpiration as a function of net radiation and temperature (Priestley-Taylor relationship) assuming an entrainment factor (ω) somewhat greater than the canonical value of 0.26. The fact that leaves in tropical forests are typically cooler than surrounding air, often already by solar noon, is consistent with a recently published comparison of MODIS day-time land-surface temperatures with air temperatures. Theory further predicts a strong dependence of leaf size (which is inversely related to leaf boundary-layer conductance, and therefore to absolute magnitude of ΔT) on moisture availability. Theoretically, leaf size should be determined by either night-time constraints (risk of frost damage to active leaves) or day-time constraints (risk of heat stress damage),with the former likely to predominate - thereby restricting the occurrence of large leaves - at high latitudes. In low latitudes, daytime maximum leaf size is predicted to increase with temperature, provided that water is plentiful. If water is restricted, however, transpiration cannot proceed at the Priestley-Taylor rate, and it quickly becomes advantageous for plants to have small leaves, which do not heat up much above the temperature of their surroundings. The difference between leaf

  16. Battery system with temperature sensors

    Energy Technology Data Exchange (ETDEWEB)

    Wood, Steven J.; Trester, Dale B.

    2012-11-13

    A battery system to monitor temperature includes at least one cell with a temperature sensing device proximate the at least one cell. The battery system also includes a flexible member that holds the temperature sensor proximate to the at least one cell.

  17. Battery system with temperature sensors

    Science.gov (United States)

    Wood, Steven J.; Trester, Dale B.

    2012-11-13

    A battery system to monitor temperature includes at least one cell with a temperature sensing device proximate the at least one cell. The battery system also includes a flexible member that holds the temperature sensor proximate to the at least one cell.

  18. Comparative Study of Influential Factors for Temperature Distribution in a Composite Bridge Cross-section%组合梁桥截面温度分布影响因素对比分析

    Institute of Scientific and Technical Information of China (English)

    张凯龙; 马如进; 陈艾荣

    2014-01-01

    This article studied thermal deformation of composite bridges .Firstly, based on geographical loca-tion and geometric characteristics of a bridge , the method to adopt solar radiation data was corrected .Numeri-cal results of temperature distribution in the cross-section were acquired by finite element modeling .Secondly , by numerical calculations , different influential factors such as pavement thickness , various thermodynamic pa-rameters of the three components of the structure , which include asphalt deck pavement , concrete deck and steel beam , were studied .It is concluded that proper thermodynamic properties of modern materials can be used to compensate of thermal deformation of a bridge .%针对某变形精确控制组合梁桥的温度变形问题,综合桥梁所处地理环境特征、桥梁结构几何构型等因素,实现对相关随机气象参数(尤其太阳辐射强度)的取值修正;进而通过对结构热环境的有限元模拟,得到截面温度分布的数值结果。以此为基础,着重探讨了三种结构材料(沥青混凝土、混凝土和钢)的相关热力学参数以及沥青混凝土铺装层厚度对截面温度分布的影响方式及程度,并就对应的荷载效应进行了定性的评估与对比。以此为指导,结合目前新型材料的优良热力学性能,工程人员可采取针对性设计或补偿措施达到降低梁体温度变形响应及优化线形的目的。

  19. Influence of selected quality factors of beef on the profile and the quantity of heterocyclic aromatic amines during processing at high temperature.

    Science.gov (United States)

    Szterk, Arkadiusz; Waszkiewicz-Robak, Bożena

    2014-03-01

    New factors were identified impacting significantly on the formation of HAA during grilling. The number and profile of HAA in grilled beef depend on the fattening system (intensive and semi-intensive), and the effect of the animal's sex. The fewest HAAs were formed in rib steak from heifers from a semi-intensive fattening system. A significant effect of storage of meat in refrigerated conditions (5 to 15 days) was also demonstrated on the formation of HAA during grilling. The longer the raw meat was stored, the more HAA was formed during grilling. The quantity of HAA was strongly correlated with the content of free amino acids and a very strong correlation was found with an increasing content of free purine and pyrimidine bases and their nucleosides. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  20. Revealing of major factors in the directional thermal radiation of ground objects--A new way for improving the precision of directional radiant temperature measuring and data analysis

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    This paper is devoted to eliminating the noise from the measuring of directional thermal radiation for ground objects.Specifically,we think that the noise is mainly due to the variance of components in the field of view of the sensor with the view angle changing and to the heat balance change on the ground during the period of measurement.The authors present two new observation methods named as "constant area method by thermal camera" and "concurrent method by dual sensors" respectively.The experiments show that the data obtained by these methods abide by some regularly directional distribution,which is totally different from the data from the former methods.The analysis of the major factors in the directionality of thermal radiation is also made in the paper.

  1. Candidemia in Patients with Body Temperature Below 37°C and Admitted to Internal Medicine Wards: Assessment of Risk Factors.

    Science.gov (United States)

    Tascini, Carlo; Falcone, Marco; Bassetti, Matteo; De Rosa, Francesco G; Sozio, Emanuela; Russo, Alessandro; Sbrana, Francesco; Ripoli, Andrea; Merelli, Maria; Scarparo, Claudio; Carmassi, Franco; Venditti, Mario; Menichetti, Francesco

    2016-12-01

    An increasing number of candidemia episodes has been reported in patients cared for in internal medicine wards. These usually older and frail patients may not be suspected as having candidemia because they lack fever at the onset of the episode. To identify the risk factors associated with the lack of fever at the onset of candidemia (ie, the collection of the first positive blood culture for Candida spp.) in patients cared for in internal medicine wards, we compared 2 group of patients with or without fever. We retrospectively review data charts from 3 tertiary care, university hospitals in Italy, comparing patients with or without fever at onset of candidemia. Consecutive candidemic episodes in afebrile patients and matched febrile controls were identified during the 3-year study period. Patient baseline characteristics and several infection-related variables were examined. Random forest analysis was used, given the number of predictors to be considered and the potential complexity of their relations with the onset of fever. We identified 147 candidemic episodes without fever at onset and 147 febrile candidemia episodes. Factors associated with the lack of fever at onset of candidemia were diabetes, Clostridium difficile infection, and a shorter delta time from internal medicine wards admission to the onset of candidemia. The only variable associated with fever was the use of intravascular devices. Quite unexpectedly, antifungal therapy was administered more frequently to patients without fever, and no differences on 30-day mortality rate were documented in the 2 study groups. Clinicians should be aware that an increasing number of patients with invasive candidiasis cared for in internal medicine wards may lack fever at onset, especially those with diabetes and C. difficile infection. Candidemia should be suspected in patients with afebrile systemic inflammatory response syndrome or in worsening clinical condition: blood cultures should be taken, and a timely

  2. Effect of dietary manganese on antioxidant status and expression levels of heat-shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures.

    Science.gov (United States)

    Zhu, Yong-Wen; Lu, Lin; Li, Wen-Xiang; Zhang, Li-Yang; Ji, Cheng; Lin, Xi; Liu, Hsiao-Ching; Odle, Jack; Luo, Xu-Gang

    2015-12-28

    To investigate the effect of Mn on antioxidant status and expression levels of heat-shock proteins/factors in tissues of laying broiler breeders subjected to heat challenge, we used a completely randomised design (n 6) with a factorial arrangement of 2 environmental temperatures (normal, 21 (sem 1)°C and high, 32 (sem 1)°C)×3 dietary Mn treatments (an Mn-unsupplemented basal diet (CON), or a basal diet supplemented with 120 mg Mn/kg diet as inorganic Mn sulphate (iMn) or organic Mn proteinate (oMn)). There were no interactions (P>0·10) between environmental temperature and dietary Mn in all of the measured indices. High temperature decreased (Pmanganese superoxide dismutase (MnSOD) activity (P<0·05) and a slight increase of malondialdehyde level (P=0·06) were detected in breast muscle. Up-regulated (P<0·05) expression levels of heat-shock factor 1 (HSF1) and HSF3 mRNA and heat-shock protein 70 (HSP70) mRNA and protein were found in all three tissues. Broiler breeders fed either iMn or oMn had higher tissue Mn content (P<0·0001), heart MnSOD and CuZnSOD activities (P<0·01) and breast muscle MnSOD protein levels (P<0·05), and lower (P<0·05) breast muscle HSP70 mRNA and protein levels than those fed CON. Broiler breeders fed oMn had higher (P<0·03) bone Mn content than those fed iMn. These results indicate that high temperature decreases Mn retention and increases HSP70 and HSF1, HSF3 expression levels in tissues of laying broiler breeders. Furthermore, dietary supplementation with Mn in either source may enhance heart antioxidant ability and inhibit the expression of HSP70 in breast muscle. Finally, the organic Mn appears to be more available than inorganic Mn for bone in laying broiler breeders regardless of environmental temperatures.

  3. Modeling temperature and moisture fields in conditioned spaces using zonal approach, including sorption phenomena in buildings materials; Modelisation thermo-hydro-aeraulique des locaux climatises selon l'approche zonale (prise en compte des phenomenes de sorption d'humidite)

    Energy Technology Data Exchange (ETDEWEB)

    Cordeiro Mendoca, K.

    2004-05-15

    Building simulation models represent in our days an important tool for building conception and performance analysis. Although moisture interacts in many ways with the whole building affecting therefore its behavior, frequently these models neglects the interactions between them. In addition, in most of them, indoor air conditions are considered uniform, which is a non-realistic assumption in conditioned spaces. In this work, a model to predict temperature and moisture fields in conditioned spaces, using zonal approach, is proposed. This method is based in dividing spatially a room in a relative small number of zones, typically on the order of tens to hundreds, where the state variables of air are considered uniform, with the exception of pressure that varies hydrostatically. While not as fine-grained as CFD simulation, zonal models do give useful information about temperature and moisture distributions that is important in comfort analysis. The proposed model was structured in three groups of sub-models representing the three building domains: indoor air, envelope and HVAC system. The indoor air sub-model is related to the indoor air space, where airflow speed can be considered weak. The envelope sub-model is related to the radiation exchanges between envelope and its neighborhood, and to the simultaneous heat and mass transfers across the envelope material. This latest can be represented by four sub-models of different complexity levels, with two of them taking into account moisture adsorption and desorption by building materials. Concerning to the HVAC system model, it refers to the whole system that means equipment, control and specific airflow from equipment. All sub-models were coupled into a modular simulation environment, SPARK, well-adapted to compare different models. The applicability of the proposed model is shown by two examples. The first one shows the importance of considering moisture sorption phenomena in the prediction of indoor air conditions

  4. MAF2 Is Regulated by Temperature-Dependent Splicing and Represses Flowering at Low Temperatures in Parallel with FLM.

    Directory of Open Access Journals (Sweden)

    Chiara A Airoldi

    Full Text Available Plants enter their reproductive phase when the environmental conditions are favourable for the successful production of progeny. The transition from vegetative to reproductive phase is influenced by several environmental factors including ambient temperature. In the model plant Arabidopsis thaliana, SHORT VEGETATIVE PHASE (SVP is critical for this pathway; svp mutants cannot modify their flowering time in response to ambient temperature. SVP encodes a MADS-box transcription factor that directly represses genes that promote flowering. SVP binds DNA in complexes with other MADS-box transcription factors, including FLOWERING LOCUS M (FLM, which acts with SVP to repress the floral transition at low temperatures. Small temperature changes post-transcriptionally regulate FLM through temperature-dependent alternative splicing (TD-AS. As ambient temperature increases, the predominant FLM splice isoform shifts to encode a protein incapable of exerting a repressive effect on flowering. Here we characterize a closely related MADS-box transcription factor, MADS AFFECTING FLOWERING2 (MAF2, which has independently evolved TD-AS. At low temperatures the most abundant MAF2 splice variant encodes a protein that interacts with SVP to repress flowering. At increased temperature the relative abundance of splice isoforms shifts in favour of an intron-retaining variant that introduces a premature termination codon. We show that this isoform encodes a protein that cannot interact with SVP or repress flowering. At lower temperatures MAF2 and SVP repress flowering in parallel with FLM and SVP, providing an additional input to sense ambient temperature for the control of flowering.

  5. High temperature materials and mechanisms

    CERN Document Server

    2014-01-01

    The use of high-temperature materials in current and future applications, including silicone materials for handling hot foods and metal alloys for developing high-speed aircraft and spacecraft systems, has generated a growing interest in high-temperature technologies. High Temperature Materials and Mechanisms explores a broad range of issues related to high-temperature materials and mechanisms that operate in harsh conditions. While some applications involve the use of materials at high temperatures, others require materials processed at high temperatures for use at room temperature. High-temperature materials must also be resistant to related causes of damage, such as oxidation and corrosion, which are accelerated with increased temperatures. This book examines high-temperature materials and mechanisms from many angles. It covers the topics of processes, materials characterization methods, and the nondestructive evaluation and health monitoring of high-temperature materials and structures. It describes the ...

  6. Imaging of axial spondyloarthritis including ankylosing spondylitis.

    Science.gov (United States)

    Braun, J; Baraliakos, X

    2011-03-01

    New bone formation of the vertebral column is pathognomonic for ankylosing spondylitis (AS), while acute and/or chronic changes in the sacroiliac joints are relevant for diagnosis. The 'gold standard' for assessment of structural changes in AS are conventional radiographs, while MRI is useful to assess inflammation. Recent MRI studies have shown that the lower half of the thoracic spine is most commonly affected in AS. Scoring tools for spinal inflammation such as the ASspiMRI-a have been proposed, successfully used in large clinical trials and compared in a multireader experiment; none was finally preferred by OMERACT. Quantification of structural spinal AS changes is performed by the modified Stokes AS Spine Score (mSASSS), which evaluates lateral cervical and lumbar radiographs. Two years was identified as the shortest possible follow-up time based on the reliability and sensitivity to change of the mSASSS. A potential disadvantage of the mSASSS is that the thoracic spine is not included. Recent data based on the mSASSS have suggested that tumour necrosis factor blockers do not inhibit radiographic progression in AS. Since the mean radiographic change is reported to be less than 1 syndesmophyte over 2 years, the sensitivity to change of the mSASSS has been questioned. However, in one study where continuous non-steroidal anti-inflammatory drugs use was compared with on-demand use, a difference between these two methods of drug intake was reported. The face and construct validity of the mSASSS has been criticised because a score of ´1´ contains a mixture of osteodestructive (erosions) and osteoproliferative changes (squaring and sclerosis). A new scoring system, the RASSS, which concentrates only on bone formation and which includes the lower part of the thoracic spine is currently being evaluated. The relationship between inflammation and new bone formation in AS has recently been investigated. Low sclerostin and DKK-1 serum levels, both inhibitors of bone

  7. 牙科用氧化锆陶瓷的低温时效及其影响因素%Low temperature degradation of dental zirconia ceramic and its influencing factors

    Institute of Scientific and Technical Information of China (English)

    浩志超

    2012-01-01

    牙科用氧化锆陶瓷由于其良好的力学性能、高温稳定性、生物安全性和低热传导率,现已广泛应用于临床,特别是后牙全冠及固定桥修复.然而,在相对较低的温度及潮湿的环境下,氧化锆发生由部分稳定的四方晶相向单斜晶向的改变,即低温时效现象,影响其力学性能.本文探讨了牙科用氧化锆的低温时效及其影响因素,并讨论了改善其抗低温时效性的途径.%Dental zirconia ceramics, with their excellent mechanical properties, high temperature stability, bio-compatibility and low thermal conductivity, have been widely used for clinical all-ceramic restorations, especially for full crown and fixed bridge of posterior teeth. However, under comparatively low temperature in humid environment, partially stabilized tetragonal zirconia ceramic tends to transform into monoclinic crystal. This phenomenon is called low temperature degradation (LTD), which will result in poor mechanical properties of the material. This article discussed the LTD phenomena of the partially stabilized tetragonal zirconia and its related influencing factors, and possible approaches to improve its low temperature degradation resistance were proposed as well.

  8. Effect of semen extender and storage temperature on ram sperm motility over time

    Science.gov (United States)

    Storage of ram semen for long period of time depends on a number of factors, including type of extender and storage temperature. A study compared the effect of semen extender and storage temperature on motility of ram semen stored for 72 h. Semen collected via electroejaculator from 5 mature Katahd...

  9. Temperature dependence of OSL decay curves: Experimental and theoretical aspects

    DEFF Research Database (Denmark)

    McKeever, S.W.S.; Bøtter-Jensen, L.; Agersnap Larsen, N.;

    1997-01-01

    The factors which affect the shape of Optically Stimulated Luminescence (OSL) decay curves are examined, both experimentally and theoretically, in an effort to understand and describe the behavior of OSL as a function of temperature. The processes considered include: (1) retrapping by shallow traps...

  10. Haemophilus influenzae Disease (Including Hib) Symptoms

    Science.gov (United States)

    ... Search The CDC Cancel Submit Search The CDC Haemophilus influenzae Disease (Including Hib) Note: Javascript is disabled or ... and Symptoms Recommend on Facebook Tweet Share Compartir Haemophilus influenzae , including Hib, disease causes different symptoms depending on ...

  11. Article Including Environmental Barrier Coating System

    Science.gov (United States)

    Lee, Kang N. (Inventor)

    2015-01-01

    An enhanced environmental barrier coating for a silicon containing substrate. The enhanced barrier coating may include a bond coat doped with at least one of an alkali metal oxide and an alkali earth metal oxide. The enhanced barrier coating may include a composite mullite bond coat including BSAS and another distinct second phase oxide applied over said surface.

  12. Static, Lightweight Includes Resolution for PHP

    NARCIS (Netherlands)

    Hills, M.A.; Klint, P.; Vinju, J.J.

    2014-01-01

    Dynamic languages include a number of features that are challenging to model properly in static analysis tools. In PHP, one of these features is the include expression, where an arbitrary expression provides the path of the file to include at runtime. In this paper we present two complementary analy

  13. NGNP/HTE full-power operation at reduced high-temperature heat exchanger temperatures.

    Energy Technology Data Exchange (ETDEWEB)

    VIlim, R.; Nuclear Engineering Division

    2009-03-12

    Operation of the Next Generation Nuclear Plant (NGNP) with reduced reactor outlet temperature at full power was investigated for the High Temperature Electrolysis (HTE) hydrogen-production application. The foremost challenge for operation at design temperature is achieving an acceptably long service life for heat exchangers. In both the Intermediate Heat Exchanger (IHX) and the Process Heat Exchanger (PHX) (referred to collectively as high temperature heat exchangers) a pressure differential of several MPa exists with temperatures at or above 850 C. Thermal creep of the heat exchanger channel wall may severely limit heat exchanger life depending on the alloy selected. This report investigates plant performance with IHX temperatures reduced by lowering reactor outlet temperature. The objective is to lower the temperature in heat transfer channels to the point where existing materials can meet the 40 year lifetime needed for this component. A conservative estimate for this temperature is believed to be about 700 C. The reactor outlet temperature was reduced from 850 C to 700 C while maintaining reactor power at 600 MWt and high pressure compressor outlet at 7 MPa. We included a previously reported design option for reducing temperature at the PHX. Heat exchanger lengths were adjusted to reflect the change in performance resulting from coolant property changes and from resizing related to operating-point change. Turbomachine parameters were also optimized for the new operating condition. An integrated optimization of the complete system including heat transfer equipment was not performed. It is estimated, however, that by performing a pinch analysis the combined plant efficiency can be increased from 35.5 percent obtained in this report to a value between 38.5 and 40.1 percent. Then after normalizing for a more than three percent decrease in commodities inventory compared to the reference plant, the commodities-normalized efficiency lies between 40.0 and 41.3. This

  14. High temperature catalytic membrane reactors

    Energy Technology Data Exchange (ETDEWEB)

    1990-03-01

    Current state-of-the-art inorganic oxide membranes offer the potential of being modified to yield catalytic properties. The resulting modules may be configured to simultaneously induce catalytic reactions with product concentration and separation in a single processing step. Processes utilizing such catalytically active membrane reactors have the potential for dramatically increasing yield reactions which are currently limited by either thermodynamic equilibria, product inhibition, or kinetic selectivity. Examples of commercial interest include hydrogenation, dehydrogenation, partial and selective oxidation, hydrations, hydrocarbon cracking, olefin metathesis, hydroformylation, and olefin polymerization. A large portion of the most significant reactions fall into the category of high temperature, gas phase chemical and petrochemical processes. Microporous oxide membranes are well suited for these applications. A program is proposed to investigate selected model reactions of commercial interest (i.e. dehydrogenation of ethylbenzene to styrene and dehydrogenation of butane to butadiene) using a high temperature catalytic membrane reactor. Membranes will be developed, reaction dynamics characterized, and production processes developed, culminating in laboratory-scale demonstration of technical and economic feasibility. As a result, the anticipated increased yield per reactor pass economic incentives are envisioned. First, a large decrease in the temperature required to obtain high yield should be possible because of the reduced driving force requirement. Significantly higher conversion per pass implies a reduced recycle ratio, as well as reduced reactor size. Both factors result in reduced capital costs, as well as savings in cost of reactants and energy.

  15. Suggestions for revised definitions of noise quantities, including quantum effects

    Science.gov (United States)

    Kerr, A. R.

    1999-03-01

    Recent advances in millimeter- and submillimeter-wavelength receivers and the development of low-noise optical amplifiers focus attention on inconsistencies and ambiguities in the standard definitions of noise quantities and the procedures for measuring them. The difficulty is caused by the zero-point (quantum) noise hf/2 W/Hz, which is present even at absolute zero temperature, and also by the nonlinear dependence at low temperature of the thermal noise power of a resistor on its physical temperature, as given by the Planck law. Until recently, these effects were insignificant in all but the most exotic experiments, and the familiar Rayleigh-Jeans noise formula P=kT W/Hz could safely be used in most situations, Now, particularly in low-noise millimeter-wave and photonic devices, the quantum noise is prominent and the nonlinearity of the Planck law can no longer be neglected. The IEEE Standard Dictionary of Electrical and Electronics Terms gives several definitions of the noise temperature of a resistor or a port, which include: 1) the physical temperature of the resistor and 2) its available noise power density divided by Boltzmann's constant-definitions which are incompatible because of the nature of the Planck radiation law. In addition, there is no indication of whether the zero-point noise should be included as part of the noise temperature. Revised definitions of the common noise quantities are suggested, which resolve the shortcomings of the present definitions. The revised definitions have only a small effect on most RF and microwave measurements, but they provide a common consistent noise terminology from dc to light frequencies.

  16. Endometrial cancer risk prediction including serum-based biomarkers

    DEFF Research Database (Denmark)

    Fortner, Renée T; Hüsing, Anika; Kühn, Tilman;

    2017-01-01

    Endometrial cancer risk prediction models including lifestyle, anthropometric, and reproductive factors have limited discrimination. Adding biomarker data to these models may improve predictive capacity; to our knowledge, this has not been investigated for endometrial cancer. Using a nested case......-control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, we investigated the improvement in discrimination gained by adding serum biomarker concentrations to risk estimates derived from an existing risk prediction model based on epidemiologic factors. Serum...... concentrations of sex steroid hormones, metabolic markers, growth factors, adipokines, and cytokines were evaluated in a step-wise backward selection process; biomarkers were retained at pdiscrimination was assessed using...

  17. Control of supply temperature

    Energy Technology Data Exchange (ETDEWEB)

    Madsen, H.; Nielsen, T.S.; Soegaard, H.T.

    1996-09-01

    For many district heating systems, e.g. the system in Hoeje Taastrup, it is desirable to minimize the supply temperature from the heat production unit(s). Lower supply temperature implies lower costs in connection with the production and distribution of heat. Factors having impact on the heat demand are for instance solar radiation, wind speed, wind direction and a climate independent part, which is a function of the time of the day/week/year. By applying an optimization strategy, which minimizes the supply temperature, it is assumed that optimal economical operation can be obtained by minimizing the supply temperature and thereby the heat losses in the system. The models and methods described in this report take such aspects into account, and can therefore be used as elements in a more efficient minimization of the supply temperature. The theoretical part of this report describes models and methods for optimal on-line control of the supply temperature in district heating systems. Some of the models and methods have been implemented - or are going to be implemented - in the computer program PRESS which is a tool for optimal control of supply temperature and forecasting of heat demand in district heating systems. The principles for using transfer function models are briefly described. The ordinary generalized predictive control (OGPC) method is reviewed, and several extensions of this method are suggested. New controller, which is called the extended generalized predictive controller (XGPC), is described. (EG) 57 refs.

  18. Superconductive articles including cerium oxide layer

    Science.gov (United States)

    Wu, Xin D.; Muenchausen, Ross E.

    1993-01-01

    A ceramic superconductor comprising a metal oxide substrate, a ceramic high temperature superconductive material, and a intermediate layer of a material having a cubic crystal structure, said layer situated between the substrate and the superconductive material is provided, and a structure for supporting a ceramic superconducting material is provided, said structure comprising a metal oxide substrate, and a layer situated over the surface of the substrate to substantially inhibit interdiffusion between the substrate and a ceramic superconducting material deposited upon said structure.

  19. Constant-Pressure Combustion Charts Including Effects of Diluent Addition

    Science.gov (United States)

    Turner, L Richard; Bogart, Donald

    1949-01-01

    Charts are presented for the calculation of (a) the final temperatures and the temperature changes involved in constant-pressure combustion processes of air and in products of combustion of air and hydrocarbon fuels, and (b) the quantity of hydrocarbon fuels required in order to attain a specified combustion temperature when water, alcohol, water-alcohol mixtures, liquid ammonia, liquid carbon dioxide, liquid nitrogen, liquid oxygen, or their mixtures are added to air as diluents or refrigerants. The ideal combustion process and combustion with incomplete heat release from the primary fuel and from combustible diluents are considered. The effect of preheating the mixture of air and diluents and the effect of an initial water-vapor content in the combustion air on the required fuel quantity are also included. The charts are applicable only to processes in which the final mixture is leaner than stoichiometric and at temperatures where dissociation is unimportant. A chart is also included to permit the calculation of the stoichiometric ratio of hydrocarbon fuel to air with diluent addition. The use of the charts is illustrated by numerical examples.

  20. Methods for Melting Temperature Calculation

    Science.gov (United States)

    Hong, Qi-Jun

    the melting temperature is a design criterion. We present in detail two examples of refractory materials. First, we demonstrate how key material properties that provide guidance in the design of refractory materials can be accurately determined via ab initio thermodynamic calculations in conjunction with experimental techniques based on synchrotron X-ray diffraction and thermal analysis under laser-heated aerodynamic levitation. The properties considered include melting point, heat of fusion, heat capacity, thermal expansion coefficients, thermal stability, and sublattice disordering, as illustrated in a motivating example of lanthanum zirconate (La2Zr2O7). The close agreement with experiment in the known but structurally complex compound La2Zr 2O7 provides good indication that the computation methods described can be used within a computational screening framework to identify novel refractory materials. Second, we report an extensive investigation into the melting temperatures of the Hf-C and Hf-Ta-C systems using ab initio calculations. With melting points above 4000 K, hafnium carbide (HfC) and tantalum carbide (TaC) are among the most refractory binary compounds known to date. Their mixture, with a general formula TaxHf 1-xCy, is known to have a melting point of 4215 K at the composition Ta4HfC 5, which has long been considered as the highest melting temperature for any solid. Very few measurements of melting point in tantalum and hafnium carbides have been documented, because of the obvious experimental difficulties at extreme temperatures. The investigation lets us identify three major chemical factors that contribute to the high melting temperatures. Based on these three factors, we propose and explore a new class of materials, which, according to our ab initio calculations, may possess even higher melting temperatures than Ta-Hf-C. This example also demonstrates the feasibility of materials screening and discovery via ab initio calculations for the

  1. Influencing factors of infrared surveying in roadway

    Institute of Scientific and Technical Information of China (English)

    CAI Kang-xu; GUO Da

    2006-01-01

    The main factors that affect infrared surveying in roadway include that property of rock, electromechanical equipments running, environmental temperature, hydrogeology and support material etc. This paper sums up the expression features of these disturbing factor through theoretical analysis and actual measurement contrasts and considers that some tunnel section does not suit to go on infrared survey, for instance, soft rock meets water to expanse, and surround rock has obviously pouring water. The basic methods had made evading disturbing of electromechanical equipments, environmental temperature and protect material etc to become possible. It is helpful that offers infrared surveying technical service for production safety better in roadway.

  2. Sensing temperature.

    Science.gov (United States)

    Sengupta, Piali; Garrity, Paul

    2013-04-22

    Temperature is an omnipresent physical variable reflecting the rotational, vibrational and translational motion of matter, what Richard Feynman called the "jiggling" of atoms. Temperature varies across space and time, and this variation has dramatic effects on the physiology of living cells. It changes the rate and nature of chemical reactions, and it alters the configuration of the atoms that make up nucleic acids, proteins, lipids and other biomolecules, significantly affecting their activity. While life may have started in a "warm little pond", as Charles Darwin mused, the organisms that surround us today have only made it this far by devising sophisticated systems for sensing and responding to variations in temperature, and by using these systems in ways that allow them to persist and thrive in the face of thermal fluctuation.

  3. Improving the strength of amalgams by including steel fibers

    Energy Technology Data Exchange (ETDEWEB)

    Cochran, Calvin T. [Hendrix College, Conway, AR 72032 (United States); Van Hoose, James R. [Siemens, Orlando, FL 32826 (United States); McGill, Preston B. [Marshall Space Flight Center, EM20, Huntsville, AL 35812 (United States); Grugel, Richard N., E-mail: richard.n.grugel@nasa.gov [Marshall Space Flight Center, EM30, Huntsville, AL 35812 (United States)

    2012-05-30

    Highlights: Black-Right-Pointing-Pointer A room temperature liquid Ga-In alloy was successfully substituted for mercury. Black-Right-Pointing-Pointer Physically sound amalgams with included steel fibers can be made. Black-Right-Pointing-Pointer A small volume fraction inclusion of fibers increased strength by {approx}20%. - Abstract: Mercury amalgams, due to their material properties, are widely and successfully used in dental practice. They are, however, also well recognized as having poor tensile strength. With the possibility of expanding amalgam applications it is demonstrated that tensile strength can be increased some 20% by including a small amount of steel fibers. Furthermore, it is shown that mercury can be replaced with a room temperature liquid gallium-indium alloy. Processing, microstructures, and mechanical test results of these novel amalgams are presented and discussed in view of means to further improve their properties.

  4. High-efficiency photovoltaic technology including thermoelectric generation

    Science.gov (United States)

    Fisac, Miguel; Villasevil, Francesc X.; López, Antonio M.

    2014-04-01

    Nowadays, photovoltaic solar energy is a clean and reliable source for producing electric power. Most photovoltaic systems have been designed and built up for use in applications with low power requirements. The efficiency of solar cells is quite low, obtaining best results in monocrystalline silicon structures, with an efficiency of about 18%. When temperature rises, photovoltaic cell efficiency decreases, given that the short-circuit current is slightly increased, and the open-circuit voltage, fill factor and power output are reduced. To ensure that this does not affect performance, this paper describes how to interconnect photovoltaic and thermoelectric technology into a single structure. The temperature gradient in the solar panel is used to supply thermoelectric cells, which generate electricity, achieving a positive contribution to the total balance of the complete system.

  5. Silicon carbide fibers and articles including same

    Energy Technology Data Exchange (ETDEWEB)

    Garnier, John E; Griffith, George W

    2015-01-27

    Methods of producing silicon carbide fibers. The method comprises reacting a continuous carbon fiber material and a silicon-containing gas in a reaction chamber at a temperature ranging from approximately 1500.degree. C. to approximately 2000.degree. C. A partial pressure of oxygen in the reaction chamber is maintained at less than approximately 1.01.times.10.sup.2 Pascal to produce continuous alpha silicon carbide fibers. Continuous alpha silicon carbide fibers and articles formed from the continuous alpha silicon carbide fibers are also disclosed.

  6. INNOVATIVE INSTRUMENTATION AND ANALYSIS OF THE TEMPERATURE MEASUREMENT FOR HIGH TEMPERATURE GASIFICATION

    Energy Technology Data Exchange (ETDEWEB)

    Seong W. Lee

    2003-09-01

    During this reporting period, the literature survey including the gasifier temperature measurement literature, the ultrasonic application and its background study in cleaning application, and spray coating process are completed. The gasifier simulator (cold model) testing has been successfully conducted. Four factors (blower voltage, ultrasonic application, injection time intervals, particle weight) were considered as significant factors that affect the temperature measurement. The Analysis of Variance (ANOVA) was applied to analyze the test data. The analysis shows that all four factors are significant to the temperature measurements in the gasifier simulator (cold model). The regression analysis for the case with the normalized room temperature shows that linear model fits the temperature data with 82% accuracy (18% error). The regression analysis for the case without the normalized room temperature shows 72.5% accuracy (27.5% error). The nonlinear regression analysis indicates a better fit than that of the linear regression. The nonlinear regression model's accuracy is 88.7% (11.3% error) for normalized room temperature case, which is better than the linear regression analysis. The hot model thermocouple sleeve design and fabrication are completed. The gasifier simulator (hot model) design and the fabrication are completed. The system tests of the gasifier simulator (hot model) have been conducted and some modifications have been made. Based on the system tests and results analysis, the gasifier simulator (hot model) has met the proposed design requirement and the ready for system test. The ultrasonic cleaning method is under evaluation and will be further studied for the gasifier simulator (hot model) application. The progress of this project has been on schedule.

  7. Low temperature (

    NARCIS (Netherlands)

    Rath, J.K.; de Jong, M.; Schropp, R.E.I.

    2008-01-01

    Amorphous silicon films have been made by HWCVD at a very low substrate temperature of ≤ 100 °C (in a dynamic substrate heating mode) without artificial substrate cooling, through a substantial increase of the filament–substrate distance ( 80 mm) and using one straight tantalum filament. The materia

  8. The correspondence between water temperature and coiling direction in Bulimina

    Science.gov (United States)

    Collins, Laurel S.

    1990-06-01

    The influence of temperature on the direction of coiling in the benthic foraminifera Bulimina marginata d'Orbigny and B. aculeata d'Orbigny is investigated by direct comparison of specimens and temperature data measured at or near the sites of collection. Nine samples from the Gulf of Mexico and 16 samples from the Gulf of Maine south to New Jersey are used. These areas include cold temperate and subtropical regions, the continental shelf, slope, and a semirestricted gulf. Complicating factors of life cycle stage and possible ontogenetic change are eliminated. Dextrality is strongly associated with warm temperatures, but cold temperatures do not produce predominantly sinistrally coiled individuals. This is the first demonstration of an unambiguous correlation between temperature and coiling direction in benthic foraminifera.

  9. Thermal buckling of axisymmetrically laminated cylindrically orthotropic shallow spherical shells including transverse shear

    Institute of Scientific and Technical Information of China (English)

    ZHU Yong-an; WANG Fan; LIU Ren-huai

    2008-01-01

    The nonlinear thermal buckling of symmetrically laminated cylindrically orthotropic shallow spherical shell under temperature field and uniform pressure including transverse shear is studied.Also the analytic formulas for determining the critical buckling loads under different temperature fields are obtained by using the modified iteration method.The effect of transverse shear deformation and different temperature fields on critical buckling load is discussed.

  10. 富血小板纤维蛋白体外释放生长因子相关因素的研究%Rich platelet fibrin release of growth factors in vitro study of the relationship with temperature

    Institute of Scientific and Technical Information of China (English)

    李艳秋; 刘金凤; 张天首; 张海鑫; 徐云

    2016-01-01

    目的:观察保存温度及离心管的材质在制备富血小板纤维体外释放生长因子中发挥的作用,优化富血小板纤维蛋白的提取方法。方法:采集志愿者的静脉血,分别使用玻璃材质的离心管和塑料材质的离心管进行离心,制备完成后将收集到的PRF分别置于4℃和37℃的环境中进行保存,收集PRF所释放的生长因子,比较不同方法得到的富血小板纤维蛋白释放的血小板衍生生长因子-AB (platelet-derived growth factor, PDGF-AB)、转化生长因子-β(transforming growth factor-β, TGF-β)的量的差异。结果:使用玻璃试管组的PRF释放的PDGF-AB和TGF-β的量高于对照组,存放于4℃条件的PRF释放的生长因子高于对照组。结论:在制备PRF时,建议使用玻璃材质的离心管储存于4℃左右的环境中,以便PRF发挥更好地促进组织生长于修复的作用。%Objective: Observation of preservation temperature and centrifugal pipe material in the prepara-tion of platelet rich fiber in vitro release of growth factors play a role ,to optimize the extraction methods of rich platelet fibrin. Method: Venous blood collection and volunteers, using glass centrifugal cen-trifuge tube and plastic centrifuge tube, after the completion of the preparation of the collected PRF re-spectively at 4 ℃ and 37 ℃ to save, collect PRF release of growth factors, to compare different ways to get rich platelet fibrin release of platelet-derived growth factor-AB (platelet-derived growth factor, PDGF-AB), transforming growth factor beta (transforming growth factor beta, TGF-beta) the amount of difference. Result:Use glass tube group PRF release PDGF-AB and TGF-the amount of beta is higher than the control group, stored at 4℃condition of PRF release of growth factor is higher than the control group. Conclusion: In the preparation of PRF, it is recommended to use glass centrifugal pipe stored at 4℃about environment, in

  11. High Temperature Piezoelectric Drill

    Science.gov (United States)

    Bao, Xiaoqi; Scott, James; Boudreau, Kate; Bar-Cohen, Yoseph; Sherrit, Stewart; Badescu, Mircea; Shrout, Tom; Zhang, Shujun

    2009-01-01

    The current NASA Decadal mission planning effort has identified Venus as a significant scientific target for a surface in-situ sampling/analyzing mission. The Venus environment represents several extremes including high temperature (460 deg C), high pressure (9 MPa), and potentially corrosive (condensed sulfuric acid droplets that adhere to surfaces during entry) environments. This technology challenge requires new rock sampling tools for these extreme conditions. Piezoelectric materials can potentially operate over a wide temperature range. Single crystals, like LiNbO3, have a Curie temperature that is higher than 1000 deg C and the piezoelectric ceramics Bismuth Titanate higher than 600 deg C. A study of the feasibility of producing piezoelectric drills that can operate in the temperature range up to 500 deg C was conducted. The study includes the high temperature properties investigations of engineering materials and piezoelectric ceramics with different formulas and doping. The drilling performances of a prototype Ultrasonic/Sonic Drill/Corer (USDC) using high temperate piezoelectric ceramics and single crystal were tested at temperature up to 500 deg C. The detailed results of our study and a discussion of the future work on performance improvements are presented in this paper.

  12. A quantal Tolman temperature

    Energy Technology Data Exchange (ETDEWEB)

    Gim, Yongwan; Kim, Wontae [Sogang University, Department of Physics, Seoul (Korea, Republic of)

    2015-11-15

    The conventional Tolman temperature based on the assumption of the traceless condition of energy-momentum tensor for matter fields is infinite at the horizon if Hawking radiation is involved. However, we note that the temperature associated with Hawking radiation is of relevance to the trace anomaly, which means that the traceless condition should be released. So, a trace anomaly-induced Stefan-Boltzmann law is newly derived by employing the first law of thermodynamics and the property of the temperature independence of the trace anomaly. Then, the Tolman temperature is quantum-mechanically generalized according to the anomaly-induced Stefan-Boltzmann law. In an exactly soluble model, we show that the Tolman factor does not appear in the generalized Tolman temperature which is eventually finite everywhere, in particular, vanishing at the horizon. It turns out that the equivalence principle survives at the horizon with the help of the quantum principle, and some puzzles related to the Tolman temperature are also resolved. (orig.)

  13. A quantal Tolman temperature

    Energy Technology Data Exchange (ETDEWEB)

    Gim, Yongwan, E-mail: yongwan89@sogang.ac.kr; Kim, Wontae, E-mail: wtkim@sogang.ac.kr [Department of Physics, Sogang University, 121-742, Seoul (Korea, Republic of)

    2015-11-24

    The conventional Tolman temperature based on the assumption of the traceless condition of energy-momentum tensor for matter fields is infinite at the horizon if Hawking radiation is involved. However, we note that the temperature associated with Hawking radiation is of relevance to the trace anomaly, which means that the traceless condition should be released. So, a trace anomaly-induced Stefan-Boltzmann law is newly derived by employing the first law of thermodynamics and the property of the temperature independence of the trace anomaly. Then, the Tolman temperature is quantum-mechanically generalized according to the anomaly-induced Stefan-Boltzmann law. In an exactly soluble model, we show that the Tolman factor does not appear in the generalized Tolman temperature which is eventually finite everywhere, in particular, vanishing at the horizon. It turns out that the equivalence principle survives at the horizon with the help of the quantum principle, and some puzzles related to the Tolman temperature are also resolved.

  14. SAW Temperature Sensor on Quartz.

    Science.gov (United States)

    Zhgoon, Sergei; Shvetsov, Alexander; Ancev, Ivan; Bogoslovsky, Sergei; Sapozhnikov, Gennadiy; Trokhimets, Konstantin; Derkach, Mikhail

    2015-06-01

    For biomedical applications, narrow temperature range and high sensor accuracy requirements define the need for high temperature sensitivity. Wireless SAW sensors connected to antennas need a reference element to account for changes in electromagnetic coupling between the transmitter and receiver antennas. A pair of sensors with different temperature sensitivities may serve as a self-referenced sensor assembly. This justifies the need for materials with useful SAW resonator properties and with the largest difference between temperature coefficients of frequency (TCF) for a resonator pair on a single substrate. We have identified several cuts of quartz having useful properties with a TCF difference up to 140 ppm/°C for a pair of resonators on a single substrate. As a rule, placing such resonators on a single substrate requires their rotation by up to 90° relative to each other. The limited range of cuts presents a unique opportunity to place both resonators along the X+90° direction with one resonator using Bleustein-Gulyaev-Shimizu (BGS) waves (with electrodes placed along the x-axis) and the other one (with electrodes inclined by about ±10° to the x-axis) using quasi-Rayleigh waves. These cuts are close to the 70°Y cut where a high TCF difference is reached together with acceptable characteristics of the resonators. Resonators were designed for all useful cuts (including the 70°Y cut) and tested. The use of different periods in reflectors and interdigital transducer (IDT) together with individual choice of gaps between reflectors and IDT meant achieving low spurious content in resonator responses. The quality factors reached values up to 3500 at central frequencies around 915 MHz for both BGS and quasi-Rayleigh types of waves. The measured difference of the TCF is about 138 ppm/°C on 70°Y cut that is close to the calculated value.

  15. Influence of the Environment on Body Temperature of Racing Greyhounds.

    Science.gov (United States)

    McNicholl, Jane; Howarth, Gordon S; Hazel, Susan J

    2016-01-01

    Heat strain is a potential risk factor for racing greyhounds in hot climates. However, there have been limited studies into the incidence of heat strain (when excess heat causes physiological or pathological effects) in racing greyhounds. The aim of this study was to determine if heat strain occurs in racing greyhounds, and, if so, whether environmental factors (e.g., ambient temperature and relative humidity) or dog-related factors (e.g., sex, bodyweight, color) are associated with the risk of heat strain. A total of 229 greyhounds were included in over 46 race meetings and seven different race venues in South Australia, Australia. Rectal temperatures of dogs were measured pre- and postrace and urine samples collected for analysis of myoglobinuria. Ambient temperature at race times ranged between 11.0 and 40.8°C and relative humidity ranged from 17 to 92%. There was a mean increase in greyhound rectal temperature of 2.1°C (range 1.1-3.1°C). A small but significant association was present between ambient temperature and increase in rectal temperature (r (2) = 0.033, P = 0.007). The mean ambient temperature at race time, of dogs with postrace rectal temperature of or exceeding 41.5°C, was significantly greater than at race time of dogs with a postrace rectal temperature ≤41.5°C (31.2 vs. 27.3°C, respectively, P = 0.004). When the ambient temperature reached 38(o)C, over one-third (39%) of dogs had a rectal temperature >41.5°C. Over half of postrace urine samples were positive by Dipstick reading for hemoglobin/myoglobin, and of 77 urine samples positive for Dipstick readings, 95% were positive for myoglobin. However, urinary myoglobin levels were not associated with ambient temperature or postrace rectal temperatures. The mean increase in rectal temperature was greater in dark (black, blue, brindle) than light (fawn and white) colored greyhounds. The results suggest heat strain occurs in racing greyhounds, evidenced by postrace rectal

  16. Lung Disease Including Asthma and Adult Vaccination

    Science.gov (United States)

    ... Healthcare Professionals Lung Disease including Asthma and Adult Vaccination Language: English Español (Spanish) Recommend on Facebook Tweet ... more about health insurance options. Learn about adult vaccination and other health conditions Asplenia Diabetes Heart Disease, ...

  17. Births and deaths including fetal deaths

    Data.gov (United States)

    U.S. Department of Health & Human Services — Access to a variety of United States birth and death files including fetal deaths: Birth Files, 1968-2009; 1995-2005; Fetal death file, 1982-2005; Mortality files,...

  18. 28 CFR 20.32 - Includable offenses.

    Science.gov (United States)

    2010-07-01

    ...., drunkenness, vagrancy, disturbing the peace, curfew violation, loitering, false fire alarm, non-specific charges of suspicion or investigation, and traffic violations (except data will be included on arrests...

  19. Including risk in the balanced scorecard

    African Journals Online (AJOL)

    kirstam

    iiSouthern African Business Review Special Edition Accounting Research 2015. Including risk in the .... customer, internal business process and learning and growth perspectives comprise ...... Boston: Harvard Business School Press. Kaplan ...

  20. Including Indigenous Minorities in Decision-Making

    DEFF Research Database (Denmark)

    Pristed Nielsen, Helene

    Based on theories of public sphere participation and deliberative democracy, this book presents empirical results from a study of experiences with including Aboriginal and Maori groups in political decision-making in respectively Western Australia and New Zealand......Based on theories of public sphere participation and deliberative democracy, this book presents empirical results from a study of experiences with including Aboriginal and Maori groups in political decision-making in respectively Western Australia and New Zealand...

  1. [Prevention of dementia (including Alzheimer's disease)].

    Science.gov (United States)

    Kornhuber, H H

    2004-05-01

    Prevention of dementia: Life expectancy still increases linearly, and the elderly part of the European population grows rapidly in relation to the young. Dementia, however, grows even more rapidly, because it increases exponentially after age 65; it will become a great burden if nothing is done. The discussion so far is concentrated on treatment, whereas prevention is neglected. The therapy of dementia, however, has limited effect. Contrary to a widespread opinion prevention is possible. Genetic factors alone dominate the fate of cognition only in about 3 % of the cases. Besides age, lifestyle and the vascular risk factors exercise a great influence. High blood pressure carries a fourfold risk, diabetes more than doubles the risk both of the vascular and of the Alzheimer type; combined even more. Especially cerebral microangiopathy is strongly associated with Alzheimer's dementia, it triggers the vicious circle which leads to amyloid deposition. The importance of the circulation is underestimated, because most of the microvascular cerebral lesions are not perceived by the patient. All the risk factors for Alzheimer's disease after age 65 are also vascular risk factors especially for microangiopathy: Apo-E4, oestrogen deficiency, insulin resistance, diabetes, arterial hypertension, high cholesterol, old age and increased plasma homocystin which is often caused by alcohol consumption even in moderate doses. A healthy life style with daily outdoor activity and a Mediterranean diet not only reduces the risk of dementia, but also of coronary death and cancer. Cognitively stimulating activity protects even more than physical activity against dementia; the basis for this is acquired in youth by education. Therapy with statins is advisable if atherosclerosis cannot be reasonably counteracted by physical activity and diet.

  2. Operating Cell Temperature Determination in Flat-Plate Photovoltaic Modules; Calculo de la Temperature de Operacion de Celulas Solares en un Panel Fotovoltaico Plano

    Energy Technology Data Exchange (ETDEWEB)

    Chenlo, F.

    2002-07-01

    Two procedures (simplified and complete) to determine the operating cell temperature in photovoltaic modules operating in real conditions assuming isothermal stationary modules are presented in this work. Some examples are included that show the dependence of this temperature on several environment (sky, ground and ambient temperatures, solar irradiance, wind speed, etc.) and structural (module geometry and size, encapsulating materials, antirreflexive optical coatings, etc) factors and also on electrical module performance. In a further step temperature profiles for non-isothermal modules are analysed besides transitory effects due to variable irradiance and wind gusts. (Author)

  3. Comparação dos fatores de risco para amputações maiores e menores em pacientes diabéticos de um Programa de Saúde da Família Comparison of risk factors for major and minor amputation in diabetic patients included in a Family Health Program

    Directory of Open Access Journals (Sweden)

    Elvira Cancio Assumpção

    2009-06-01

    Full Text Available CONTEXTO: Dentre as maiores causas de internamento hospitalar em pacientes com diabetes melito tipos 1 e 2 estão as complicações do pé diabético, principalmente pelas sequelas, muitas vezes incapacitantes, destacando-se as amputações de membros inferiores. A insuficiência vascular periférica ocorre mais precocemente nesses pacientes. A coexistência de neuropatia, isquemia e imunodeficiência favorece o desenvolvimento de infecções nos membros inferiores, que, se não tratadas adequadamente, podem levar a amputações e até à morte. OBJETIVOS: Comparar os fatores de risco para amputações maiores e menores em pacientes diabéticos de um Programa de Saúde da Família do CAIC Virgem dos Pobres III, em Maceió, AL. MÉTODOS: Foram examinados 93 pacientes com o diagnóstico de diabetes melito, sendo avaliada a realização ou não de amputações de membros inferiores. As variáveis analisadas foram: sexo, idade, tipo do diabetes, pressão arterial, amputação prévia (se maior ou menor, alterações dermatológicas, alterações de pulsos arteriais pedioso e tibial posterior, deformidades e neuropatia, e foram classificadas de acordo com a classificação de Wagner e de Texas. RESULTADOS: Todos os pacientes eram diabéticos tipo 2. Verificou-se que 4,30% dos pacientes evoluíram para amputação de membros inferiores. Não se observou variação significativa da hipertensão, deformidades e neuropatia em relação ao grupo de pacientes que foram amputados. Entretanto, a ausência de detecção dos pulsos distais dos membros inferiores revelou-se bastante significativa com relação ao desfecho de amputação. CONCLUSÃO: Deve-se proporcionar aos diabéticos um atendimento ambulatorial adequado para que seja possível prevenir ou minimizar tais complicações.BACKGROUND: The main causes of hospital admission in patients with type 1 and 2 diabetes mellitus include diabetic foot complications, which may result in particularly disabling

  4. Analysis of Climatic Factors Influencing Walnut Distribution in the Main Producing Areas of Yunnan Province

    Institute of Scientific and Technical Information of China (English)

    Liangjun; XIAO; Ting; MA; Delu; Ning

    2013-01-01

    Using the data of 11 climatic factors on 40 counties in the main producing areas of walnut of Yunnan Province,we analyze the impact of various climatic factors on the distribution of Yunnan walnut.The results show that Yunnan walnut has a great expectation on temperature and moisture.Temperature,including average temperature in January,average temperature in July,the average annual temperature and accumulated temperature≥10℃,has the greatest impact on the distribution of Yunnan walnut,and is the primary dominant factor;moisture,including annual rainfall and average relative humidity,has a great impact on the distribution of Yunnan walnut,and is the secondary dominant factor.

  5. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Science.gov (United States)

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

    1996-11-01

    The dilemma of designing an advanced undergraduate laboratory lies in the desire to teach and reinforce basic principles and techniques while at the same time exposing students to the excitement of research. We report here on a one-semester, project-based biochemistry laboratory that combines the best features of a cookbook approach (high success rate, achievement of defined goals) with those of an investigative, discovery-based approach (student involvement in the experimental design, excitement of real research). Individual modules may be selected and combined to meet the needs of different courses and different institutions. The central theme of this lab is protein purification and design. This laboratory accompanies the first semester of biochemistry (Structure and Function of Macromolecules, a course taken mainly by junior and senior chemistry and biological chemistry majors). The protein chosen as the object of study is the enzyme lysozyme, which is utilized in all projects. It is suitable for a student lab because it is easily and inexpensively obtained from egg white and is extremely stable, and its high isoelectric point (pI = 11) allows for efficient separation from other proteins by ion-exchange chromatography. Furthermore, a literature search conducted by the resourceful student reveals a wealth of information, since lysozyme has been the subject of numerous studies. It was the first enzyme whose structure was determined by crystallography (1). Hendrickson et al. (2) have previously described an intensive one-month laboratory course centered around lysozyme, although their emphasis is on protein stability rather than purification and engineering. Lysozyme continues to be the focus of much exciting new work on protein folding and dynamics, structure and activity (3 - 5). This lab course includes the following features: (i) reinforcement of basic techniques, such as preparation of buffers, simple enzyme kinetics, and absorption spectroscopy; (ii

  6. temperature overspecification

    Directory of Open Access Journals (Sweden)

    Mehdi Dehghan

    2001-01-01

    Full Text Available Two different finite difference schemes for solving the two-dimensional parabolic inverse problem with temperature overspecification are considered. These schemes are developed for indentifying the control parameter which produces, at any given time, a desired temperature distribution at a given point in the spatial domain. The numerical methods discussed, are based on the (3,3 alternating direction implicit (ADI finite difference scheme and the (3,9 alternating direction implicit formula. These schemes are unconditionally stable. The basis of analysis of the finite difference equation considered here is the modified equivalent partial differential equation approach, developed from the 1974 work of Warming and Hyett [17]. This allows direct and simple comparison of the errors associated with the equations as well as providing a means to develop more accurate finite difference schemes. These schemes use less central processor times than the fully implicit schemes for two-dimensional diffusion with temperature overspecification. The alternating direction implicit schemes developed in this report use more CPU times than the fully explicit finite difference schemes, but their unconditional stability is significant. The results of numerical experiments are presented, and accuracy and the Central Processor (CPU times needed for each of the methods are discussed. We also give error estimates in the maximum norm for each of these methods.

  7. Desulfurization at high temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Panula-Nikkilae, E.; Kurkela, E.; Mojtahedi, W.

    1987-01-01

    Two high-temperature desulfurization methods, furnace injection and gasification-desulfurization are presented. In furnace injection, the efficiency of desulfurization is 50-60%, but this method is applied in energy production plants, where flue gas desulfurization cannot be used. Ca-based sorbents are used as desulfurization material. Factors affecting desulfurization and the effect of injection on the boiler and ash handling are discussed. In energy production based on gasification, very low sulfur emissions can be achieved by conventional low-temperature cleanup. However, high-temperature gas cleaning leads to higher efficiency and can be applied to smaller size classes. Ca-, Fe-, or Zn-based sorbents or mixed metals can be used for desulfurization. Most of the methods under development are based on the use of regenerative sorbents in a cleanup reactor located outside the gasifier. So far, only calcium compounds have been used for desulfurization inside the gasifier.

  8. Electric Power Monthly, August 1990. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-29

    The Electric Power Monthly (EPM) presents monthly summaries of electric utility statistics at the national, Census division, and State level. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data includes generation by energy source (coal, oil, gas, hydroelectric, and nuclear); generation by region; consumption of fossil fuels for power generation; sales of electric power, cost data; and unusual occurrences. A glossary is included.

  9. Electrochemical cell structure including an ionomeric barrier

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, Timothy N.; Hibbs, Michael

    2017-06-20

    An apparatus includes an electrochemical half-cell comprising: an electrolyte, an anode; and an ionomeric barrier positioned between the electrolyte and the anode. The anode may comprise a multi-electron vanadium phosphorous alloy, such as VP.sub.x, wherein x is 1-5. The electrochemical half-cell is configured to oxidize the vanadium and phosphorous alloy to release electrons. A method of mitigating corrosion in an electrochemical cell includes disposing an ionomeric barrier in a path of electrolyte or ion flow to an anode and mitigating anion accumulation on the surface of the anode.

  10. Magnetic properties of nickel halide hydrates including deuteration effects

    Science.gov (United States)

    DeFotis, G. C.; Van Dongen, M. J.; Hampton, A. S.; Komatsu, C. H.; Trowell, K. T.; Havas, K. C.; Davis, C. M.; DeSanto, C. L.; Hays, K.; Wagner, M. J.

    2017-01-01

    Magnetic measurements on variously hydrated nickel chlorides and bromides, including deuterated forms, are reported. Results include locations and sizes of susceptibility maxima, Tmax and χmax, ordering temperatures Tc, Curie constants and Weiss theta in the paramagnetic regime, and primary and secondary exchange interactions from analysis of low temperature data. For the latter a 2D Heisenberg model augmented by interlayer exchange in a mean-field approximation is applied. Magnetization data to 16 kG as a function of temperature show curvature and hysteresis characteristics quite system dependent. For four materials high field magnetization data to 70 kG at 2.00 K are also obtained. Comparison is made with theoretical relations for spin-1 models. Trends are apparent, primarily that Tmax of each bromide hydrate is less than for the corresponding chloride, and that for a given halide nD2O (n=1 or 2) deuterates exhibit lesser Tmax than do nH2O hydrates. A monoclinic unit cell determined from powder X-ray diffraction data on NiBr2·2D2O is different from and slightly larger than that of NiBr2·2H2O. This provides some rationale for the difference in magnetic properties between these.

  11. Fault of the correction factor for pressure and temperature k{sub PT} in the atmospheric conditions of Dosimetric Calibration Lab. - LSCD of ININ - Mexico; Falla del factor de correcion por presion y temperatura k{sub PT} a las condiciones atmosfericas del LSCD-ININ-Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez R, Jose T.; Jesus Cejudo, A.; La Cruz H., Daniel de; Tovar M, Victor M., E-mail: trinidad.alvarez@inin.gob.mx, E-mail: jesus.cejudo@inin.gob.mx, E-mail: daniel.delacruz@inin.gob.mx, E-mail: victor.tovar@inin.gob.mx [Instituto Nacional de Investigaciones Nucleares (LSCD/ININ), Ocoyoacac (Mexico). Laboratorio Secundario de Calibracion Dosimetrica

    2013-07-01

    The realization of the operational quantities H*, Hp y/0 H'(0.07) for estimating the effective dose E, usually is done by measuring the air kerma Ka air within the field of ionizing radiation of interest and was subsequently applied appropriate conversion factors for both the quality of radiation and the operational quantity of interest. However, the SSDL in performing the Ka to environmental conditions of ININ (3000 m above sea level, P ∼ 710 hPa) with ionization chambers has found that the pressure correction factor and kPT temperature is not sufficient to correct the change in air density. Indeed, in the case of {sup 60}Co the discrepancy between the measurement of a primary standard graphite walls Ka (BEV CC01 be 131) and a side of the plastic walls (Exradin A12) is on the order of 0.4% for the case of the RX BIPM qualities to 100,135, 180 and 250 kV. It was found that for a camera model 30001 PTW (PMMA graphite wall) is needed an additional correction factor k PT ranging from 0.4% to 1.5%, correction factor calculated by MC simulation. For Sk of {sup 125}I brachytherapy sources was given an additional correction lower in 11% compared to conventional k{sub PT} value measured with a well chamber Standard Imaging HDR 1000 plus. Finally, it is in the process of studying the behavior of this additional correction factor to the case of {sup 137}Cs.

  12. Does the Response of Leaf Photosynthetic Productivity to Rising Atmospheric Temperature and CO2 Scale Up to the Canopy?

    Science.gov (United States)

    Theory predicts that interacting increases in temperature and CO2 will synergistically enhance leaf photosynthesis but how this interaction will scale to affect canopy and ecosystem productivity is less clear. Numerous factors contribute to this uncertainty including higher canopy temperatures from ...

  13. The Case for Strategies that Include Men

    African Journals Online (AJOL)

    The Case for Strategies that Include Men. Denise M Roth and .... one set of approaches advocated using medical cri- teria to identify and ... planning, offering services for the prevention and ..... are equipped with the basic minimum needed to respond to ..... Lane SD Television minidramas: social marketing and evaluation in ...

  14. Musculoskeletal ultrasound including definitions for ultrasonographic pathology

    DEFF Research Database (Denmark)

    Wakefield, RJ; Balint, PV; Szkudlarek, Marcin

    2005-01-01

    Ultrasound (US) has great potential as an outcome in rheumatoid arthritis trials for detecting bone erosions, synovitis, tendon disease, and enthesopathy. It has a number of distinct advantages over magnetic resonance imaging, including good patient tolerability and ability to scan multiple joint...

  15. An acoustic finite element including viscothermal effects

    NARCIS (Netherlands)

    Nijhof, M.J.J.; Wijnant, Y.H.; Boer, de A.

    2007-01-01

    In acoustics it is generally assumed that viscous- en thermal boundary layer effects play a minor role in the propagation of sound waves. Hence, these effects are neglected in the basic set of equations describing the sound field. However, for geometries that include small confinements of air or thi

  16. 47 CFR 65.820 - Included items.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Included items. 65.820 Section 65.820 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERSTATE RATE...) Cash working capital. The average amount of investor-supplied capital needed to provide funds for...

  17. Nuclear Chemistry: Include It in Your Curriculum.

    Science.gov (United States)

    Atwood, Charles H.; Sheline, R. K.

    1989-01-01

    Some of the topics that might be included in a nuclear chemistry section are explored. Offers radioactivity, closed shells in nuclei, energy of nuclear processes, nuclear reactions, and fission and fusion as topics of interest. Provided are ideas and examples for each. (MVL)

  18. Including the Excluded: One School for All.

    Science.gov (United States)

    EFA 2000 Bulletin, 1998

    1998-01-01

    This issue of "EFA 2000" focuses on the theme of inclusive education, i.e., including children with disabilities in general education classrooms. The cover story discusses a 1995 UNESCO survey of 63 countries that showed that integration of children with disabilities in regular schools is a declared policy in almost every country.…

  19. Innovative Instrumentation and Analysis of the Temperature Measurement for High Temperature Gasification

    Energy Technology Data Exchange (ETDEWEB)

    Seong W. Lee

    2006-09-30

    The project entitled, ''Innovative Instrumentation and Analysis of the Temperature Measurement for High Temperature Gasification'', was successfully completed by the Principal Investigator, Dr. S. Lee and his research team in the Center for Advanced Energy Systems and Environmental Control Technologies at Morgan State University. The major results and outcomes were presented in semi-annual progress reports and annual project review meetings/presentations. Specifically, the literature survey including the gasifier temperature measurement, the ultrasonic application in cleaning application, and spray coating process and the gasifier simulator (cold model) testing has been successfully conducted during the first year. The results show that four factors (blower voltage, ultrasonic application, injection time intervals, particle weight) were considered as significant factors that affect the temperature measurement. Then the gasifier simulator (hot model) design and the fabrication as well as the systematic tests on hot model were completed to test the significant factors on temperature measurement in the second year. The advanced Industrial analytic methods such as statistics-based experimental design, analysis of variance (ANOVA) and regression methods were applied in the hot model tests. The results show that operational parameters (i.e. air flow rate, water flow rate, fine dust particle amount, ammonia addition) presented significant impact on the temperature measurement inside the gasifier simulator. The experimental design and ANOVA are very efficient way to design and analyze the experiments. The results show that the air flow rate and fine dust particle amount are statistically significant to the temperature measurement. The regression model provided the functional relation between the temperature and these factors with substantial accuracy. In the last year of the project period, the ultrasonic and subsonic cleaning methods and coating

  20. 中国近百年地面温度变化自然因子的因果链分析%The Causal Chain Analysis of Natural Factors for China Sur face Temperature Variation during the Recent 100 Years

    Institute of Scientific and Technical Information of China (English)

    朱玉祥; 赵亮

    2014-01-01

    采用格兰杰(Granger)因果检验法,从自然因素的角度,即从天文因子(太阳黑子数SSN)和地球运动因子(地极移动X方向和Y方向)的角度,对我国近百年地面温度(TC)的变化进行了归因分析。所得结果如下:滞后1~11年内, SSN都不是TC的Granger原因;对于TC和极移X方向,当滞后6年时信度最高,此时极移X方向是TC的Granger原因(87%信度)。研究结果可能暗示,极移X方向的变化可能会导致6年后中国地面气温的变化。%The attribution analysis of China surface temperature(TC) in the recent 100 years is done from the angle of the astronomical factor(sunspot number, SSN) and the earth movement factor(polar shift x direction and y direction ) by using Granger causality test. The results are as follows:(1) SSN is not the Granger cause of TC in all of 1 to 11 years lags;(2) when the lag is 6 years, conifdence is the highest, at this time polar shift x direction is the Granger cause of TC (87%conifdence);(3) when the lag is 12 years, TC is the Granger cause of the polar shift y direction, the conifdence is 86%. The research results of the paper suggest that the change of polar shift x direction possibly results in the change of TC, and the change of TC possibly inlfuences the change of the polar shift y direction.

  1. Robust factorization

    DEFF Research Database (Denmark)

    Aanæs, Henrik; Fisker, Rune; Åström, Kalle;

    2002-01-01

    Factorization algorithms for recovering structure and motion from an image stream have many advantages, but they usually require a set of well-tracked features. Such a set is in generally not available in practical applications. There is thus a need for making factorization algorithms deal...... effectively with errors in the tracked features. We propose a new and computationally efficient algorithm for applying an arbitrary error function in the factorization scheme. This algorithm enables the use of robust statistical techniques and arbitrary noise models for the individual features....... These techniques and models enable the factorization scheme to deal effectively with mismatched features, missing features, and noise on the individual features. The proposed approach further includes a new method for Euclidean reconstruction that significantly improves convergence of the factorization algorithms...

  2. Experimental temperature manipulations alter songbird autumnal nocturnal migratory restlessness

    Directory of Open Access Journals (Sweden)

    Berchtold Adrienne

    2017-02-01

    Full Text Available Migrating birds may respond to a variety of environmental cues in order to time migration. During the migration season nocturnally migrating songbirds may migrate or stop-over at their current location, and when migrating they may vary the rate or distance of migration on any given night. It has long been known that a variety of weather-related factors including wind speed and direction, and temperature, are correlated with migration in free-living birds, however these variables are often correlated with each other. In this study we experimentally manipulated temperature to determine if it would directly modulate nocturnal migratory restlessness in songbirds. We experimentally manipulated temperature between 4, 14, and 24°C and monitored nocturnal migratory restlessness during autumn in white-throated sparrows (Zonotrichia albicollis. White-throated sparrows are relatively shortdistance migrants with a prolonged autumnal migration, and we thus predicted they might be sensitive to weatherrelated cues when deciding whether to migrate or stopover. At warm temperatures (24°C none of the birds exhibited migratory restlessness. The probability of exhibiting migratory restlessness, and the intensity of this restlessness (number of infra-red beam breaks increased at cooler (14°C, 4°C temperatures. These data support the hypothesis that one of the many factors that birds use when making behavioural decisions during migration is temperature, and that birds can respond to temperature directly independently of other weather-related cues.

  3. Rotor assembly including superconducting magnetic coil

    Energy Technology Data Exchange (ETDEWEB)

    Snitchler, Gregory L. (Shrewsbury, MA); Gamble, Bruce B. (Wellesley, MA); Voccio, John P. (Somerville, MA)

    2003-01-01

    Superconducting coils and methods of manufacture include a superconductor tape wound concentrically about and disposed along an axis of the coil to define an opening having a dimension which gradually decreases, in the direction along the axis, from a first end to a second end of the coil. Each turn of the superconductor tape has a broad surface maintained substantially parallel to the axis of the coil.

  4. Electric power monthly, September 1990. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-17

    The purpose of this report is to provide energy decision makers with accurate and timely information that may be used in forming various perspectives on electric issues. The power plants considered include coal, petroleum, natural gas, hydroelectric, and nuclear power plants. Data are presented for power generation, fuel consumption, fuel receipts and cost, sales of electricity, and unusual occurrences at power plants. Data are compared at the national, Census division, and state levels. 4 figs., 52 tabs. (CK)

  5. A Lumped Thermal Model Including Thermal Coupling and Thermal Boundary Conditions for High Power IGBT Modules

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Ma, Ke; Blaabjerg, Frede

    2017-01-01

    Detailed thermal dynamics of high power IGBT modules are important information for the reliability analysis and thermal design of power electronic systems. However, the existing thermal models have their limits to correctly predict these complicated thermal behavior in the IGBTs: The typically used...... thermal distribution under long-term studies. Meanwhile the boundary conditions for the thermal analysis are modeled and included, which can be adapted to different real field applications of power electronic converters. Finally, the accuracy of the proposed thermal model is verified by FEM simulations...... thermal model based on one-dimensional RC lumps have limits to provide temperature distributions inside the device, moreover some variable factors in the real-field applications like the cooling and heating conditions of the converter cannot be adapted. On the other hand, the more advanced three...

  6. A Lumped Thermal Model Including Thermal Coupling and Thermal Boundary Conditions for High Power IGBT Modules

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Ma, Ke; Blaabjerg, Frede

    2017-01-01

    Detailed thermal dynamics of high power IGBT modules are important information for the reliability analysis and thermal design of power electronic systems. However, the existing thermal models have their limits to correctly predict these complicated thermal behavior in the IGBTs: The typically used...... thermal distribution under long-term studies. Meanwhile the boundary conditions for the thermal analysis are modeled and included, which can be adapted to different real-field applications of power electronic converters. Finally, the accuracy of the proposed thermal model is verified by FEM simulations...... thermal model based on one-dimensional RC lumps have limits to provide temperature distributions inside the device, moreover some variable factors in the real-field applications like the cooling and heating conditions of the converter cannot be adapted. On the other hand, the more advanced three...

  7. High Temperature Capacitor Development

    Energy Technology Data Exchange (ETDEWEB)

    John Kosek

    2009-06-30

    The absence of high-temperature electronics is an obstacle to the development of untapped energy resources (deep oil, gas and geothermal). US natural gas consumption is projected to grow from 22 trillion cubic feet per year (tcf) in 1999 to 34 tcf in 2020. Cumulatively this is 607 tcf of consumption by 2020, while recoverable reserves using current technology are 177 tcf. A significant portion of this shortfall may be met by tapping deep gas reservoirs. Tapping these reservoirs represents a significant technical challenge. At these depths, temperatures and pressures are very high and may require penetrating very hard rock. Logistics of supporting 6.1 km (20,000 ft) drill strings and the drilling processes are complex and expensive. At these depths up to 50% of the total drilling cost may be in the last 10% of the well depth. Thus, as wells go deeper it is increasingly important that drillers are able to monitor conditions down-hole such as temperature, pressure, heading, etc. Commercial off-the-shelf electronics are not specified to meet these operating conditions. This is due to problems associated with all aspects of the electronics including the resistors and capacitors. With respect to capacitors, increasing temperature often significantly changes capacitance because of the strong temperature dependence of the dielectric constant. Higher temperatures also affect the equivalent series resistance (ESR). High-temperature capacitors usually have low capacitance values because of these dielectric effects and because packages are kept small to prevent mechanical breakage caused by thermal stresses. Electrolytic capacitors do not operate at temperatures above 150oC due to dielectric breakdown. The development of high-temperature capacitors to be used in a high-pressure high-temperature (HPHT) drilling environment was investigated. These capacitors were based on a previously developed high-voltage hybridized capacitor developed at Giner, Inc. in conjunction with a

  8. A Quantal Tolman Temperature

    CERN Document Server

    Gim, Yongwan

    2015-01-01

    The conventional Tolman temperature based on the assumption of the traceless condition of energy-momentum tensor for matter fields is infinite at the horizon if the Hawking radiation is involved for a black hole. However, we note that the temperature associated with the Hawking radiation is of relevance to the trace anomaly, which means that the traceless condition should be released. Thus, a trace anomaly-induced Stefan-Boltzmann law is newly derived by employing the first law of thermodynamics and the property of the temperature independence of the trace anomaly. Then, the Tolman temperature is naturally modified according to the anomaly-induced Stefan-Boltzmann law. In an exactly soluble model, we show that the Tolman factor does not appear in the modified Tolman temperature which is eventually finite everywhere, in particular, vanishing at the horizon. It turns out that the equivalence principle survives at the horizon with the help of the quantum principle, and some puzzles related to the Tolman temperat...

  9. Temperature in the throat

    Directory of Open Access Journals (Sweden)

    Dariush Kaviani

    2016-09-01

    Full Text Available We study the temperature of extended objects in string theory. Rotating probe D-branes admit horizons and temperatures a la Unruh effect. We find that the induced metrics on slow rotating probe D1-branes in holographic string solutions including warped Calabi–Yau throats have distinct thermal horizons with characteristic Hawking temperatures even if there is no black hole in the bulk Calabi–Yau. Taking the UV/IR limits of the solution, we show that the world volume black hole nucleation depends on the deformation and the warping of the throat. We find that world volume horizons and temperatures of expected features form not in the regular confining IR region but in the singular nonconfining UV solution. In the conformal limit of the UV, we find horizons and temperatures similar to those on rotating probes in the AdS throat found in the literature. In this case, we also find that activating a background gauge field form the U(1 R-symmetry modifies the induced metric with its temperature describing two different classes of black hole solutions.

  10. Opioid dependence treatment, including buprenorphine/naloxone.

    Science.gov (United States)

    Raisch, Dennis W; Fye, Carol L; Boardman, Kathy D; Sather, Mike R

    2002-02-01

    To review opioid dependence (OD) and its treatment. Pharmacologic treatments, including the use of buprenorphine/naloxone, are presented. Pharmaceutical care functions for outpatient OD treatment are discussed. Primary and review articles were identified by MEDLINE and HEALTHSTAR searches (from 1966 to November 2000) and through secondary sources. Tertiary sources were also reviewed regarding general concepts of OD and its treatment. Relevant articles were reviewed after identification from published abstracts. Articles were selected based on the objectives for this article. Studies of the treatment of OD with buprenorphine were selected based on the topic (pharmacology, pharmacokinetics, adverse reactions) and study design (randomized, controlled clinical trials in patients with OD with active/placebo comparisons and/or comparisons of active OD treatments). Articles regarding pharmacists' activities in the treatment and prevention of OD were reviewed for the pharmaceutical care section. OD is considered a medical disorder with costly adverse health outcomes. Although methadone maintenance treatment (MMT) is cost-effective for OD, only about 12% of individuals with OD receive this treatment. Psychological and pharmacologic modalities are used to treat OD, but patients often relapse. Drug therapy includes alpha 2-agonists for withdrawal symptoms, detoxification regimens with or without opioids, opioid antagonists, and opioid replacement including methadone, levomethadyl acetate, and buprenorphine. The Drug Addiction Treatment Act of 1999 allows for office-based opioid replacement therapies. Sublingual buprenorphine with naloxone can be used in this milieu. Buprenorphine with naloxone is currently under new drug application review with the Food and Drug Administration. Clinical research shows buprenorphine to be equal in effectiveness to methadone, but safer in overdose due to its ceiling effect on respiratory depression. It has lower abuse potential and fewer

  11. Musculoskeletal ultrasound including definitions for ultrasonographic pathology

    DEFF Research Database (Denmark)

    Wakefield, RJ; Balint, PV; Szkudlarek, Marcin

    2005-01-01

    Ultrasound (US) has great potential as an outcome in rheumatoid arthritis trials for detecting bone erosions, synovitis, tendon disease, and enthesopathy. It has a number of distinct advantages over magnetic resonance imaging, including good patient tolerability and ability to scan multiple joints...... pathologies. This article presents the first report from the OMERACT ultrasound special interest group, which has compared US against the criteria of the OMERACT filter. Also proposed for the first time are consensus US definitions for common pathological lesions seen in patients with inflammatory arthritis....

  12. Drug delivery device including electrolytic pump

    KAUST Repository

    Foulds, Ian G.

    2016-03-31

    Systems and methods are provided for a drug delivery device and use of the device for drug delivery. In various aspects, the drug delivery device combines a “solid drug in reservoir” (SDR) system with an electrolytic pump. In various aspects an improved electrolytic pump is provided including, in particular, an improved electrolytic pump for use with a drug delivery device, for example an implantable drug delivery device. A catalytic reformer can be incorporated in a periodically pulsed electrolytic pump to provide stable pumping performance and reduced actuation cycle.

  13. 影响窝箱环境的因素及窝箱温度与仔貂早期死亡率的关系%Factors Affecting the Cage Environment and the Relationship Between Cage Temperature and Early Kit Mortality

    Institute of Scientific and Technical Information of China (English)

    张琳; 杨福合; 邢秀梅; 刘宗岳

    2011-01-01

    本研究旨在探讨影响妊娠期、哺乳期窝箱温度的因素和窝箱环境与仔貂早期死亡率的关系.选用160只已配种的大连金州水貂,按配种日期和体重随机分为6组,即新型窝箱(A、AB、AC、AD)和传统窝箱(B1、B2),测定不同外界环境条件下水貂分娩前后窝箱的箱内温度,调查统计分娩后1~14日龄内仔貂的死亡率,利用曲线回归分析各组窝箱内温度和相对湿度的变化规律.结果表明:①妊娠期新型窝箱内温度高于传统窝箱B1组,尤其在外界环境温度较低时差异显著(P<0.05);传统窝箱内的湿度高于新犁窝箱.②哺乳期新犁窝箱的箱内温度高于传统窝箱B1组,B2组箱内温度高于B1组;各组窝箱内湿度相差不大.③新型窝箱的仔貂平均死亡率低于传统窝箱B1组,B2组仔貂平均死亡率低于B1组.结论:新犁窝箱的保温性能优于传统窝箱,妊娠期的窝箱温度主要受外界环境温度和窝箱保温性能的影响.哺乳期的窝箱温度主要受母貂母性强弱、窝箱保温性能、外界环境温度因素的影响;窝箱温度维持在12℃以上能明显降低仔貂因体温过低而死亡的概率.%The objective of this study was to discuss the factors that affect the cage temperature and assess the effects of cage temperature on mortality rate of early kit's life. The Experiment was conducted to select 160 mating minks and mode up of 6 treatments in term of mating date and body weight. Individually housed female mink had either new types including A, AB, A and AD or traditional types including B1 and B2 respectively. We measured the cage temperature of the new types (A, AB, AC, AD) and traditional types (BI, B2) in different environmental climate, at the same time we assessed the mortality rate of new born minks during 1 to 14 day before parturition. We analyze the cage temperature pattern through curve estimation. The result indicated that :① In pregnancy the cage temperature of new

  14. Inlet Guide Vane Wakes Including Rotor Effects

    Science.gov (United States)

    Johnston, R. T.; Fleeter, S.

    2001-02-01

    Fundamental experiments are described directed at the investigation of forcing functions generated by an inlet guide vane (IGV) row, including interactions with the downstream rotor, for application to turbomachine forced response design systems. The experiments are performed in a high-speed research fan facility comprised of an IGV row upstream of a rotor. IGV-rotor axial spacing is variable, with the IGV row able to be indexed circumferentially, thereby allowing measurements to be made across several IGV wakes. With an IGV relative Mach number of 0.29, measurements include the IGV wake pressure and velocity fields for three IGV-rotor axial spacings. The decay characteristics of the IGV wakes are compared to the Majjigi and Gliebe empirical correlations. After Fourier decomposition, a vortical-potential gust splitting analysis is implemented to determine the vortical and potential harmonic wake gust forcing functions both upstream and downstream of the rotor. Higher harmonics of the vortical gust component of the IGV wakes are found to decay at a uniform rate due to viscous diffusion.

  15. Including supplementary elements in a compositional biplot

    Science.gov (United States)

    Daunis-i-Estadella, J.; Thió-Henestrosa, S.; Mateu-Figueras, G.

    2011-05-01

    The biplot is a widely and powerful methodology used with multidimensional data sets to describe and display the relationships between observations and variables in an easy way. Compositional data are vectors with positive components, whose sum is constant because they represent a relative contribution of different parts to a whole; due to this property standard biplots cannot be performed with compositional data, instead of a previous transformation of the data is performed. In this paper, we extend the compositional biplot defined by Aitchison and Greenacre (2002), in order to include in the display supplementary elements which are not used in the definition of the compositional biplot. Different types of supplementary elements are considered: supplementary parts of the composition, supplementary continuous variables external to the composition, supplementary categorical variables and supplementary observations. The projection of supplementary parts of the composition is done by means of the equivalence of clr and lr biplots. The other supplementary projections are done by classical methodology. An application example with a real geological data is included.

  16. New generation concretes including reactive powder concretes

    Directory of Open Access Journals (Sweden)

    Stefania Grzeszczyk

    2015-09-01

    Full Text Available Based on a broad literature review, this paper presents characteristics of new generation composites on the basis of cements which are applied in engineering structures and in rehabilitation of structures. The role of cement, microfillers, superplasticizers and fibers in the above stated composites i.e. factors which allow for the maximum packing of particles in the cement matrix and a minimum pore volume, and the increase in composite bending strength, have been discussed. Special attention was paid to Reactive Powder Concrete in which coarse aggregate was replaced by ground quartz and sand. Such composites contain active microfillers and the applied new-generation superplasticizers allow us to decrease the water-cement ratio in the composite up to 0.2. Whereas, steel fibre additive allows us to significantly improve the bending strength.The paper presents the properties of the excellent Ductal — a composite from Reactive Powder Concrete, which at compressive strength from 180 to 230 MPa achieves the tensile strength of 30 to 50 MPa. Its application allows us to create slim profiles and tall light and slender, and simultaneously durable and corrosion-resistant structural elements of considerable span. This paper gives a few examples of Ductal application in practice.[b]Keywords[/b]: civil engineering, composite materials, reactive powder concrete

  17. High-Temperature Piezoelectric Crystals for Acoustic Wave Sensor Applications.

    Science.gov (United States)

    Zu, Hongfei; Wu, Huiyan; Wang, Qing-Ming

    2016-03-01

    In this review paper, nine different types of high-temperature piezoelectric crystals and their sensor applications are overviewed. The important materials' properties of these piezoelectric crystals including dielectric constant, elastic coefficients, piezoelectric coefficients, electromechanical coupling coefficients, and mechanical quality factor are discussed in detail. The determination methods of these physical properties are also presented. Moreover, the growth methods, structures, and properties of these piezoelectric crystals are summarized and compared. Of particular interest are langasite and oxyborate crystals, which exhibit no phase transitions prior to their melting points ∼ 1500 °C and possess high electrical resistivity, piezoelectric coefficients, and mechanical quality factor at ultrahigh temperature ( ∼ 1000 °C). Finally, some research results on surface acoustic wave (SAW) and bulk acoustic wave (BAW) sensors developed using this high-temperature piezoelectric crystals are discussed.

  18. Mortality and neurological outcome in the elderly after target temperature management for out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Winther-Jensen, Matilde; Pellis, Tommaso; Kuiper, Michael;

    2015-01-01

    AIM: To assess older age as a prognostic factor in patients resuscitated from out-of-hospital-cardiac arrest (OHCA) and the interaction between age and level of target temperature management. METHODS AND RESULTS: 950 patients included in the target temperature management (TTM) trial were randomly...... age groups, p = 0.001, the same was true for ST segment elevation on ECG at admission, p ....5-5.0, p target temperature...

  19. Estimation of Joule heating effect on temperature and pressure distribution in electrokinetic-driven microchannel flows.

    Science.gov (United States)

    Chein, Reiyu; Yang, Yeong Chin; Lin, Yushan

    2006-02-01

    In this study we present simple analytical models that predict the temperature and pressure variations in electrokinetic-driven microchannel flow under the Joule heating effect. For temperature prediction, a simple model shows that the temperature is related to the Joule heating parameter, autothermal Joule heating parameter, external cooling parameter, Peclet number, and the channel length to channel hydraulic diameter ratio. The simple model overpredicted the thermally developed temperature compared with the full numerical simulation, but in good agreement with the experimental measurements. The factors that affect the external cooling parameters, such as the heat transfer coefficient, channel configuration, and channel material are also examined based on this simple model. Based on the mass conservation, a simple model is developed that predicts the pressure variations, including the temperature effect. An adverse pressure gradient is required to satisfy the mass conservation requirement. The temperature effect on the pressure gradient is via the temperature-dependent fluid viscosity and electroosmotic velocity.

  20. Temperature based Restricted Boltzmann Machines.

    Science.gov (United States)

    Li, Guoqi; Deng, Lei; Xu, Yi; Wen, Changyun; Wang, Wei; Pei, Jing; Shi, Luping

    2016-01-13

    Restricted Boltzmann machines (RBMs), which apply graphical models to learning probability distribution over a set of inputs, have attracted much attention recently since being proposed as building blocks of multi-layer learning systems called deep belief networks (DBNs). Note that temperature is a key factor of the Boltzmann distribution that RBMs originate from. However, none of existing schemes have considered the impact of temperature in the graphical model of DBNs. In this work, we propose temperature based restricted Boltzmann machines (TRBMs) which reveals that temperature is an essential parameter controlling the selectivity of the firing neurons in the hidden layers. We theoretically prove that the effect of temperature can be adjusted by setting the parameter of the sharpness of the logistic function in the proposed TRBMs. The performance of RBMs can be improved by adjusting the temperature parameter of TRBMs. This work provides a comprehensive insights into the deep belief networks and deep learning architectures from a physical point of view.

  1. Critical point anomalies include expansion shock waves

    Energy Technology Data Exchange (ETDEWEB)

    Nannan, N. R., E-mail: ryan.nannan@uvs.edu [Mechanical Engineering Discipline, Anton de Kom University of Suriname, Leysweg 86, PO Box 9212, Paramaribo, Suriname and Process and Energy Department, Delft University of Technology, Leeghwaterstraat 44, 2628 CA Delft (Netherlands); Guardone, A., E-mail: alberto.guardone@polimi.it [Department of Aerospace Science and Technology, Politecnico di Milano, Via La Masa 34, 20156 Milano (Italy); Colonna, P., E-mail: p.colonna@tudelft.nl [Propulsion and Power, Delft University of Technology, Kluyverweg 1, 2629 HS Delft (Netherlands)

    2014-02-15

    From first-principle fluid dynamics, complemented by a rigorous state equation accounting for critical anomalies, we discovered that expansion shock waves may occur in the vicinity of the liquid-vapor critical point in the two-phase region. Due to universality of near-critical thermodynamics, the result is valid for any common pure fluid in which molecular interactions are only short-range, namely, for so-called 3-dimensional Ising-like systems, and under the assumption of thermodynamic equilibrium. In addition to rarefaction shock waves, diverse non-classical effects are admissible, including composite compressive shock-fan-shock waves, due to the change of sign of the fundamental derivative of gasdynamics.

  2. Reconnection experiments including 3D magnetic nulls

    Science.gov (United States)

    Le, A.; Egedal, J.; Vrublevskis, A.

    2010-11-01

    A rich collection of magnetic reconnection scenarios is possible in three dimensions depending on the topological and geometric structure of the magnetic field [1]. In recent experiments at the Versatile Toroidal Facility (VTF) three-dimensional effects were essential even in nearly axisymmetric plasmas with a non-vanishing toroidal field [2]. To explore reconnection in 3D geometries including magnetic null points, a new adjustable set of coils will be installed in the vacuum chamber of VTF. The range of vacuum magnetic field topologies attainable in VTF will be explored numerically. Plasma reconnection experiments will be run in these configurations, and measurements will be presented if available. [4pt] [1] CE Parnell, et al., (2009) ``Three-Dimensional Magnetic Reconnection, in Magnetic Coupling between the Interior and the Atmosphere of the Sun,'' eds. S.S. Hasan and R.J. Rutten, Springer-Verlag, Heidelberg, Berlin. [0ex] [2] Katz, N. et al., (2010) Phys. Rev. Lett. 104, 255004.

  3. Thermovoltaic semiconductor device including a plasma filter

    Science.gov (United States)

    Baldasaro, Paul F.

    1999-01-01

    A thermovoltaic energy conversion device and related method for converting thermal energy into an electrical potential. An interference filter is provided on a semiconductor thermovoltaic cell to pre-filter black body radiation. The semiconductor thermovoltaic cell includes a P/N junction supported on a substrate which converts incident thermal energy below the semiconductor junction band gap into electrical potential. The semiconductor substrate is doped to provide a plasma filter which reflects back energy having a wavelength which is above the band gap and which is ineffectively filtered by the interference filter, through the P/N junction to the source of radiation thereby avoiding parasitic absorption of the unusable portion of the thermal radiation energy.

  4. CLIC expands to include the Southern Hemisphere

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    Australia has recently joined the CLIC collaboration: the enlargement will bring new expertise and resources to the project, and is especially welcome in the wake of CERN budget redistributions following the recent adoption of the Medium Term Plan.   The countries involved in CLIC collaboration With the signing of a Memorandum of Understanding on 26 August 2010, the ACAS network (Australian Collaboration for Accelerator Science) became the 40th member of in the multilateral CLIC collaboration making Australia the 22nd country to join the collaboration. “The new MoU was signed by the ACAS network, which includes the Australian Synchrotron and the University of Melbourne”, explains Jean-Pierre Delahaye, CLIC Study Leader. “Thanks to their expertise, the Australian institutes will contribute greatly to the CLIC damping rings and the two-beam test modules." Institutes from any country wishing to join the CLIC collaboration are invited to assume responsibility o...

  5. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course pr...

  6. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of "LabView Basic I" and "LabView Intermediate II" trainings have been recently changed to include, respectively, an introduction and an expert training on the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to develop expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course prepare...

  7. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course prepares participants to develop test and measurement, da...

  8. Should Broca's area include Brodmann area 47?

    Science.gov (United States)

    Ardila, Alfredo; Bernal, Byron; Rosselli, Monica

    2017-02-01

    Understanding brain organization of speech production has been a principal goal of neuroscience. Historically, brain speech production has been associated with so-called Broca’s area (Brodmann area –BA- 44 and 45), however, modern neuroimaging developments suggest speech production is associated with networks rather than with areas. The purpose of this paper was to analyze the connectivity of BA47 ( pars orbitalis) in relation to language . A meta-analysis was conducted to assess the language network in which BA47 is involved. The Brainmap database was used. Twenty papers corresponding to 29 experimental conditions with a total of 373 subjects were included. Our results suggest that BA47 participates in a “frontal language production system” (or extended Broca’s system). The BA47  connectivity found is also concordant with a minor role in language semantics. BA47 plays a central role in the language production system.

  9. ACCREDITATION FOR TECHNICAL ABILITIES INCLUDING COMPUTER SKILLS

    Directory of Open Access Journals (Sweden)

    Halit Hami OZ

    2013-01-01

    Full Text Available Sector Skills are defined by state-sponsored, employer-led organizations that cover specific economic sectors in the European Union and other countries in the world to reduce skills gaps and shortages, improve productivity, boost the skills of their sector workforces and improve learning supply. The accreditation and registration systems used by professional bodies raise the profile of the profession. In many countries including the European Union, professional associations are beginning to accept practice-based accreditation, generally as an alternative to their mainstream systems. Besides studying the certain agencies in the European Union for assessing/accreditating practical abilities , Accreditation for practical abilities of Information Communication Technology and Business Management/Language domains developed by Accreditation Council for Practical abilities are also studied in detail as an example to establish a similar agency in Turkey.

  10. AMS at the ANU including biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Fifield, L.K.; Allan, G.L.; Cresswell, R.G.; Ophel, T.R. [Australian National Univ., Canberra, ACT (Australia); King, S.J.; Day, J.P. [Manchester Univ. (United Kingdom). Dept. of Chemistry

    1993-12-31

    An extensive accelerator mass spectrometry program has been conducted on the 14UD accelerator at the Australian National University since 1986. In the two years since the previous conference, the research program has expanded significantly to include biomedical applications of {sup 26}Al and studies of landform evolution using isotopes produced in situ in surface rocks by cosmic ray bombardment. The system is now used for the measurement of {sup 10}Be, {sup 14}C, {sup 26}Al, {sup 36}Cl, {sup 59}Ni and {sup 129}I, and research is being undertaken in hydrology, environmental geochemistry, archaeology and biomedicine. On the technical side, a new test system has permitted the successful off-line development of a high-intensity ion source. A new injection line to the 14UD has been established and the new source is now in position and providing beams to the accelerator. 4 refs.

  11. DEVELOPMENT OF WATER CIRCULATION MODEL INCLUDING IRRIGATION

    Science.gov (United States)

    Kotsuki, Shunji; Tanaka, Kenji; Kojiri, Toshiharu; Hamaguchi, Toshio

    It is well known that since agricultural water withdrawal has much affect on water circulation system, accurate analysis of river discharge or water balance are difficult with less regard for it. In this study, water circulation model composed of land surface model and distributed runoff model is proposed at 10km 10km resolution. In this model, irrigation water, which is estimated with land surface model, is introduced to river discharge analysis. The model is applied to the Chao Phraya River in Thailand, and reproduced seasonal water balance. Additionally, the discharge on dry season simulated with the model is improved as a result of including irrigation. Since the model, which is basically developed from global data sets, simulated seasonal change of river discharge, it can be suggested that our model has university to other river basins.

  12. The surgery of peripheral nerves (including tumors)

    DEFF Research Database (Denmark)

    Fugleholm, Kåre

    2013-01-01

    Surgical pathology of the peripheral nervous system includes traumatic injury, entrapment syndromes, and tumors. The recent significant advances in the understanding of the pathophysiology and cellular biology of peripheral nerve degeneration and regeneration has yet to be translated into improved...... surgical techniques and better outcome after peripheral nerve injury. Decision making in peripheral nerve surgery continues to be a complex challenge, where the mechanism of injury, repeated clinical evaluation, neuroradiological and neurophysiological examination, and detailed knowledge of the peripheral...... nervous system response to injury are prerequisite to obtain the best possible outcome. Surgery continues to be the primary treatment modality for peripheral nerve tumors and advances in adjuvant oncological treatment has improved outcome after malignant peripheral nerve tumors. The present chapter...

  13. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course pr...

  14. Optimization of Confectionary Sunflower Cultivation Technology by 5 Factors Including Sowing Time, Density, and Nitrogen, Phosphate and Potassium Fertilizers%播种期、密度、氮肥、磷肥、钾肥五因子对食用向日葵栽培技术的优化

    Institute of Scientific and Technical Information of China (English)

    白苇; 杨素梅; 尹海峰; 靳涛; 崔金丽; 张宝英

    2015-01-01

    采用五因子二次回归正交旋转组合设计,研究了冀西北地区播种期、密度、氮肥、磷肥、钾肥对食用向日葵产量的影响。试验单因子效应结果表明:播种期和氮肥在五因子中作用较大。试验两因子互作效应结果表明:氮肥和磷肥、磷肥和钾肥、密度和钾肥3对互作效应较大。食用向日葵高产栽培技术的最佳综合农艺组合为:播种期6月6~7日,密度33195~34305株/hm2,氮肥117.9~127.8 kg/hm2,磷肥51.2~52.8 kg/hm2,钾肥108.3~113.4 kg/hm2,适宜的 N︰P2O5︰K2O 平均为1︰0.41︰0.91。采用该组合试验示范,较当地传统种植模式增产5.8%~9.5%。%The effects of sowing time, density, and nitrogen, phosphate and potassium fertilizers on the yield of confectionary sunflowers were studied adopting five-factor quadratic regression orthogonal rotation combination design in northwest of Hebei. The results of experimental single factor effect showed that the effects of sowing time and nitrogen fertilizer were higher in the five factors. The results of the interaction effect of two experiment factors showed that the interaction effects between the nitrogen fertilizer and phosphate fertilizer, between the phosphate fertilizer and potassium fertilizer, and between the density and potassium fertilizer are higher. The optimal comprehensive agronomic combination in the confectionary sunflower high-yield cultivation technology is as follows: the sewing time is June 6th to June 7th, the density is 33 195 to 34 305 plants/hm2, the nitrogen fertilizer is 117.9~127.8 kg/hm2, the phosphate fertilizer is 51.2~52.8 kg/hm2, the potassium fertil-izer is 108.3~113.4 kg/hm2, and the proper average ratio of N︰P2O5︰K2O is 1︰0.21︰0.91. By adopting the combination in the experimental demonstration, the yield was 5.8%~9.5% higher than that of the local traditional planting pattern.

  15. High-Temperature Piezoelectric Sensing

    Directory of Open Access Journals (Sweden)

    Xiaoning Jiang

    2013-12-01

    Full Text Available Piezoelectric sensing is of increasing interest for high-temperature applications in aerospace, automotive, power plants and material processing due to its low cost, compact sensor size and simple signal conditioning, in comparison with other high-temperature sensing techniques. This paper presented an overview of high-temperature piezoelectric sensing techniques. Firstly, different types of high-temperature piezoelectric single crystals, electrode materials, and their pros and cons are discussed. Secondly, recent work on high-temperature piezoelectric sensors including accelerometer, surface acoustic wave sensor, ultrasound transducer, acoustic emission sensor, gas sensor, and pressure sensor for temperatures up to 1,250 °C were reviewed. Finally, discussions of existing challenges and future work for high-temperature piezoelectric sensing are presented.

  16. Traumatic intrusion of permanent teeth. Part 2. A clinical study of the effect of preinjury and injury factors, such as sex, age, stage of root development, tooth location, and extent of injury including number of intruded teeth on 140 intruded permanent teeth.

    Science.gov (United States)

    Andreasen, Jens Ove; Bakland, Leif K; Andreasen, Frances Meriam

    2006-04-01

    A prospective study of 140 intruded permanent teeth was done to evaluate the following healing complications: pulp necrosis (PN), root resorption (surface, inflammatory and replacement resorption) (RR) and defects in marginal periodontal healing (MA). These complications were related to various preinjury and injury factors. Age appeared to be related to all three healing complications in that patients younger than 12 years had the lowest complication rate. Stage of root formation at the time of the injury was very strongly related to PN and MA, with immature root formation (i.e. incomplete root formation or completed root formation with wide open apex) having better prognosis than more mature root development. Lateral incisors showed significantly more defects in MA, a finding possibly explained by the observation that lateral incisors were more often involved in multiple intrusions compared to other teeth and noting that multiple intrusions had a significantly higher frequency of MA. An associated crown fracture with exposed dentin resulted in more frequent PN, a finding possibly related to bacterial invasion through dentinal tubules into an ischemic pulp. The presence of a gingival laceration added to both PN and MA. The extent of intrusion (in mm) showed some relation to both RR with intrusion 1-3 mm having the lowest frequency of RR, whereas PN and MA showed no significant relation to the extent of intrusion. Finally, multiple adjacent intruded teeth were more frequently involved in a significantly greater loss of interproximal marginal bone (MA) than single intrusions. In conclusion, the relationship between healing complications and preinjury and injury factors could generally be explained by better healing possibilities in teeth with immature root formation. A possible explanation for that could be the softer bone surrounding the tooth, whereby trauma to the periodontium might be diminished.

  17. Seepage Model for PA Including Dift Collapse

    Energy Technology Data Exchange (ETDEWEB)

    G. Li; C. Tsang

    2000-12-20

    The purpose of this Analysis/Model Report (AMR) is to document the predictions and analysis performed using the Seepage Model for Performance Assessment (PA) and the Disturbed Drift Seepage Submodel for both the Topopah Spring middle nonlithophysal and lower lithophysal lithostratigraphic units at Yucca Mountain. These results will be used by PA to develop the probability distribution of water seepage into waste-emplacement drifts at Yucca Mountain, Nevada, as part of the evaluation of the long term performance of the potential repository. This AMR is in accordance with the ''Technical Work Plan for Unsaturated Zone (UZ) Flow and Transport Process Model Report'' (CRWMS M&O 2000 [153447]). This purpose is accomplished by performing numerical simulations with stochastic representations of hydrological properties, using the Seepage Model for PA, and evaluating the effects of an alternative drift geometry representing a partially collapsed drift using the Disturbed Drift Seepage Submodel. Seepage of water into waste-emplacement drifts is considered one of the principal factors having the greatest impact of long-term safety of the repository system (CRWMS M&O 2000 [153225], Table 4-1). This AMR supports the analysis and simulation that are used by PA to develop the probability distribution of water seepage into drift, and is therefore a model of primary (Level 1) importance (AP-3.15Q, ''Managing Technical Product Inputs''). The intended purpose of the Seepage Model for PA is to support: (1) PA; (2) Abstraction of Drift-Scale Seepage; and (3) Unsaturated Zone (UZ) Flow and Transport Process Model Report (PMR). Seepage into drifts is evaluated by applying numerical models with stochastic representations of hydrological properties and performing flow simulations with multiple realizations of the permeability field around the drift. The Seepage Model for PA uses the distribution of permeabilities derived from air injection testing in

  18. The Arabidopsis thaliana vernalization response requires a polycomb-like protein complex that also includes VERNALIZATION INSENSITIVE 3.

    Science.gov (United States)

    Wood, Craig C; Robertson, Masumi; Tanner, Greg; Peacock, W James; Dennis, Elizabeth S; Helliwell, Chris A

    2006-09-26

    In Arabidopsis thaliana, the promotion of flowering by cold temperatures, vernalization, is regulated via a floral-repressive MADS box transcription factor, FLOWERING LOCUS C (FLC). Vernalization leads to the epigenetic repression of FLC expression, a process that requires the polycomb group (PcG) protein VERNALIZATION 2 (VRN2) and the plant homeodomain protein VERNALIZATION INSENSITIVE 3 (VIN3). We demonstrate that the repression of FLC by vernalization requires homologues of other Polycomb Repressive Complex 2 proteins and VRN2. We show in planta that VRN2 and VIN3 are part of a large protein complex that can include the PcG proteins FERTILIZATION INDEPENDENT ENDOSPERM, CURLY LEAF, and SWINGER. These findings suggest a single protein complex is responsible for histone deacetylation at FLC and histone methylation at FLC in vernalized plants. The abundance of the complex increases during vernalization and declines after plants are returned to higher temperatures, consistent with the complex having a role in establishing FLC repression.

  19. Temperature environment for 9975 packages stored in KAC

    Energy Technology Data Exchange (ETDEWEB)

    Daugherty, W. L. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-09-10

    Plutonium materials are stored in the K Area Complex (KAC) in shipping packages, typically the 9975 shipping package. In order to estimate realistic degradation rates for components within the shipping package (i.e. the fiberboard overpack and O-ring seals), it is necessary to understand actual facility temperatures, which can vary daily and seasonally. Relevant facility temperature data available from several periods throughout its operating history have been reviewed. The annual average temperature within the Crane Maintenance Area has ranged from approximately 70 to 74 °F, although there is significant seasonal variation and lesser variation among different locations within the facility. The long-term average degradation rate for 9975 package components is very close to that expected if the component were to remain continually at the annual average temperature. This result remains valid for a wide range of activation energies (which describes the variation in degradation rate as the temperature changes), if the activation energy remains constant over the seasonal range of component temperatures. It is recommended that component degradation analyses and service life estimates incorporate these results. Specifically, it is proposed that future analyses assume an average facility ambient air temperature of 94 °F. This value is bounding for all packages, and includes margin for several factors such as increased temperatures within the storage arrays, the addition of more packages in the future, and future operational changes.

  20. Engine lubrication circuit including two pumps

    Science.gov (United States)

    Lane, William H.

    2006-10-03

    A lubrication pump coupled to the engine is sized such that the it can supply the engine with a predetermined flow volume as soon as the engine reaches a peak torque engine speed. In engines that operate predominately at speeds above the peak torque engine speed, the lubrication pump is often producing lubrication fluid in excess of the predetermined flow volume that is bypassed back to a lubrication fluid source. This arguably results in wasted power. In order to more efficiently lubricate an engine, a lubrication circuit includes a lubrication pump and a variable delivery pump. The lubrication pump is operably coupled to the engine, and the variable delivery pump is in communication with a pump output controller that is operable to vary a lubrication fluid output from the variable delivery pump as a function of at least one of engine speed and lubrication flow volume or system pressure. Thus, the lubrication pump can be sized to produce the predetermined flow volume at a speed range at which the engine predominately operates while the variable delivery pump can supplement lubrication fluid delivery from the lubrication pump at engine speeds below the predominant engine speed range.

  1. Extending Newtonian Dynamics to Include Stochastic Processes

    Science.gov (United States)

    Zak, Michail

    2009-01-01

    A paper presents further results of continuing research reported in several previous NASA Tech Briefs articles, the two most recent being Stochastic Representations of Chaos Using Terminal Attractors (NPO-41519), [Vol. 30, No. 5 (May 2006), page 57] and Physical Principle for Generation of Randomness (NPO-43822) [Vol. 33, No. 5 (May 2009), page 56]. This research focuses upon a mathematical formalism for describing post-instability motions of a dynamical system characterized by exponential divergences of trajectories leading to chaos (including turbulence as a form of chaos). The formalism involves fictitious control forces that couple the equations of motion of the system with a Liouville equation that describes the evolution of the probability density of errors in initial conditions. These stabilizing forces create a powerful terminal attractor in probability space that corresponds to occurrence of a target trajectory with probability one. The effect in configuration space (ordinary three-dimensional space as commonly perceived) is to suppress exponential divergences of neighboring trajectories without affecting the target trajectory. As a result, the post-instability motion is represented by a set of functions describing the evolution of such statistical quantities as expectations and higher moments, and this representation is stable.

  2. Odontogenic fibroma, including amyloid and ossifying variants.

    Science.gov (United States)

    Eversole, Lewis R

    2011-12-01

    Sixty-five cases of odontogenic fibroma (OdonF) are herein presented having been segregated into peripheral, extra bony tumors (n = 40) and tumors arising in bone or centrally (n = 25). All cases were characterized microscopically by a fibrous proliferation that varied within and between cases in cellularity and collagen fibril diameter, with intermixed odontogenic epithelial islands and cords. All central lesions presented as well demarcated radiolucencies and resorption of contiguous tooth roots was a common finding. These intraosseous lesions were of the WHO type; the so-called nonWHO type was excluded as all lesions with this diagnosis were devoid of an epithelial component and could be reclassified as other soft tissue fibrogenic tumors. Neither the central tumors nor the peripheral lesions recurred following enucleation/curettage, with a mean follow-up of 4 and 3.4 years respectively. Three distinct microscopic variations were encountered in this series: (1) two cases of OdonF with giant cell reaction, (2) two instances of OdonF with ossifying fibroma; and (3) four instances of OdonF with odontogenic ameloblast-associated protein (ODAM), an amyloid-like protein found deposited adjacent to epithelial cords plus CD1a+/S-100+ Langerhans dendritic cells entwined around the epithelial element. A single instance of the odontogenic fibroma-like hamartoma/enamel hypoplasia syndrome has been included in this series.

  3. Locomotive Assignment Optimization Including Train Delays

    Directory of Open Access Journals (Sweden)

    Sandra Kasalica

    2013-10-01

    Full Text Available Intention– Cyclic locomotive assignment planning is a specific type of organization of locomotive usage, and in fact, it means putting the complete workload to a closed chain, which is repeated periodically. The concept of cyclic locomotive assignment planning type organization in the area of train traction has proven in practice as the best one, but as it is made for in-advance defined timetable and without considering the stochastic nature of the timetable realization process, it leads to incompatibility in using locomotives. Methodology – Methodology defined in this paper contains: research of train delays on the Serbian Railways and Montenegrin Railways networks, analysis of the real system organization of locomotive usage in conditions of train delays, theoretical thesis of solving the problem of optimal cyclic locomotive assignment planning in conditions of train delays, designing of a model with algorithms, preparing the software package, testing the model and program with results, as well as the conclusions drawn from the complete research project. Results– The optimization model of cyclic locomotive assignment planning during the process of making timetable including train delays has been defined. Conclusion –The obtained results have shown as expected, that the larger delays of trains required a larger number of locomotives. However, by using this model it is possible to optimize the required number of locomotives, taking into account the real time delays of trains.

  4. Low-temperature-induced expression of rice ureidoglycolate amidohydrolase is mediated by a C-repeat/dehydration-responsive element that specifically interacts with rice C-repeat-binding factor 3

    Directory of Open Access Journals (Sweden)

    Juan eLi

    2015-11-01

    Full Text Available Nitrogen recycling and redistribution are important for the environmental stress response of plants. In non nitrogen-fixing plants, ureide metabolism is crucial to nitrogen recycling from organic sources. Various studies have suggested that the rate-limiting components of ureide metabolism respond to environmental stresses. However, the underlying regulation mechanism is not well understood. In this report, rice ureidoglycolate amidohydrolase (OsUAH, which is a recently identified enzyme catalyzing the final step of ureide degradation, was identified as low-temperature- (LT but not abscisic acid- (ABA regulated. To elucidate the LT regulatory mechanism at the transcriptional level, we isolated and characterized the promoter region of OsUAH (POsUAH. Series deletions revealed that a minimal region between -522 and -420 relative to the transcriptional start site was sufficient for the cold induction of POsUAH. Detailed analyses of this 103-bp fragment indicated that a C-repeat/dehydration-responsive (CRT/DRE element localized at position -434 was essential for LT-responsive expression. A rice C-repeat-binding factors/DRE-binding proteins 1 (CBFs/DREB1s subfamily member, OsCBF3, was screened to specifically bind to the CRT/DRE element in the minimal region both in yeast one-hybrid assays and in in vitro gel-shift analysis. Moreover, the promoter could be exclusively trans-activated by the interaction between the CRT/DRE element and OsCBF3 in vivo. These findings may help to elucidate the regulation mechanism of stress-responsive ureide metabolism genes and provide an example of the member-specific manipulation of the CBF/DREB1 subfamily.

  5. Late-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway.

    Science.gov (United States)

    Wang, Xia; Chang, Qingyun; Wang, Yu; Su, Feng; Zhang, Shicui

    2014-12-01

    Two different mechanisms are considered to be related to aging. Cumulative molecular damage caused by reactive oxygen species (ROS), the by-products of oxidative phosphorylation, is one of these mechanisms (ROS concept). Deregulated nutrient sensing by the insulin/insulin-like growth factor 1 (IGF-1) signaling (IIS) pathway is the second mechanism (IIS concept). Temperature reduction (TR) is known to modulate aging and prolong life span in a variety of organisms, but the mechanisms remain poorly defined. Here we first demonstrate that late-onset TR from 26 °C to 22 °C extends mean life span and maximum life span by approximately 5.2 and 3 weeks, respectively, in the annual fish Nothobranchius guentheri. We then show that TR is able to decrease the accumulation of the histological aging markers senescence-associated β-galactosidase (SA-β-Gal) in the epithelium and lipofuscin (LF) in the liver and to reduce protein oxidation and lipid peroxidation levels in the muscle. We also show that TR can enhance the activities of catalase, glutathione peroxidase, and superoxide dismutase, and stimulate the synthesis of SirT1 and FOXO3A/FOXO1A, both of which are the downstream regulators of the IIS pathway. Taken together, our findings suggest that late-onset TR, a simple non-intrusion intervention, can retard the aging process in aged fish, resulting in their life span extension, via a synergistic action of an anti-oxidant system and the IIS pathway. This also suggests that combined assessment of the ROS and IIS concepts will contribute to providing a more comprehensive view of the anti-aging process.

  6. Radiant Temperature Nulling Radiometer

    Science.gov (United States)

    2002-01-01

    A nulling, self-calibrating infrared radiometer is being developed for use in noncontact measurement of temperature in any of a variety of industrial and scientific applications. This instrument is expected to be especially well-suited to measurement of ambient or near-ambient temperature and, even more specifically, for measuring the surface temperature of a natural body of water. Although this radiometer would utilize the long-wavelength infrared (LWIR) portion of the spectrum (wavelengths of 8 to 12 m), its basic principle of operation could also be applied to other spectral bands (corresponding to other temperature ranges) in which the atmosphere is transparent and in which design requirements for sensitivity and temperature-measurement accuracy could be satisfied. The underlying principle of nulling and self-calibration is the same as that of a typical microwave radiometer, but because of differences between the characteristics of signals in the infrared and microwave spectral regions, the principle must be implemented in a different way. A detailed description of the instrument including an infrared photodetector equipped with focusing input optics [e.g., lens(es) and/or mirrors] and an input LWIR band-pass filter is presented.

  7. High temperature materials; Materiaux a hautes temperatures

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The aim of this workshop is to share the needs of high temperature and nuclear fuel materials for future nuclear systems, to take stock of the status of researches in this domain and to propose some cooperation works between the different research organisations. The future nuclear systems are the very high temperature (850 to 1200 deg. C) gas cooled reactors (GCR) and the molten salt reactors (MSR). These systems include not only the reactor but also the fabrication and reprocessing of the spent fuel. This document brings together the transparencies of 13 communications among the 25 given at the workshop: 1) characteristics and needs of future systems: specifications, materials and fuel needs for fast spectrum GCR and very high temperature GCR; 2) high temperature materials out of neutron flux: thermal barriers: materials, resistance, lifetimes; nickel-base metal alloys: status of knowledge, mechanical behaviour, possible applications; corrosion linked with the gas coolant: knowledge and problems to be solved; super-alloys for turbines: alloys for blades and discs; corrosion linked with MSR: knowledge and problems to be solved; 3) materials for reactor core structure: nuclear graphite and carbon; fuel assembly structure materials of the GCR with fast neutron spectrum: status of knowledge and ceramics and cermets needs; silicon carbide as fuel confinement material, study of irradiation induced defects; migration of fission products, I and Cs in SiC; 4) materials for hydrogen production: status of the knowledge and needs for the thermochemical cycle; 5) technologies: GCR components and the associated material needs: compact exchangers, pumps, turbines; MSR components: valves, exchangers, pumps. (J.S.)

  8. High temperature storage loop :

    Energy Technology Data Exchange (ETDEWEB)

    Gill, David Dennis; Kolb, William J.

    2013-07-01

    A three year plan for thermal energy storage (TES) research was created at Sandia National Laboratories in the spring of 2012. This plan included a strategic goal of providing test capability for Sandia and for the nation in which to evaluate high temperature storage (>650ÀC) technology. The plan was to scope, design, and build a flow loop that would be compatible with a multitude of high temperature heat transfer/storage fluids. The High Temperature Storage Loop (HTSL) would be reconfigurable so that it was useful for not only storage testing, but also for high temperature receiver testing and high efficiency power cycle testing as well. In that way, HTSL was part of a much larger strategy for Sandia to provide a research and testing platform that would be integral for the evaluation of individual technologies funded under the SunShot program. DOEs SunShot program seeks to reduce the price of solar technologies to 6/kWhr to be cost competitive with carbon-based fuels. The HTSL project sought to provide evaluation capability for these SunShot supported technologies. This report includes the scoping, design, and budgetary costing aspects of this effort

  9. High temperature storage loop :

    Energy Technology Data Exchange (ETDEWEB)

    Gill, David Dennis; Kolb, William J.

    2013-07-01

    A three year plan for thermal energy storage (TES) research was created at Sandia National Laboratories in the spring of 2012. This plan included a strategic goal of providing test capability for Sandia and for the nation in which to evaluate high temperature storage (>650ÀC) technology. The plan was to scope, design, and build a flow loop that would be compatible with a multitude of high temperature heat transfer/storage fluids. The High Temperature Storage Loop (HTSL) would be reconfigurable so that it was useful for not only storage testing, but also for high temperature receiver testing and high efficiency power cycle testing as well. In that way, HTSL was part of a much larger strategy for Sandia to provide a research and testing platform that would be integral for the evaluation of individual technologies funded under the SunShot program. DOEs SunShot program seeks to reduce the price of solar technologies to 6/kWhr to be cost competitive with carbon-based fuels. The HTSL project sought to provide evaluation capability for these SunShot supported technologies. This report includes the scoping, design, and budgetary costing aspects of this effort

  10. Exergoeconomic performance optimization for a steady-flow endoreversible refrigeration model including six typical cycles

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Lingen; Kan, Xuxian; Sun, Fengrui; Wu, Feng [College of Naval Architecture and Power, Naval University of Engineering, Wuhan 430033 (China)

    2013-07-01

    The operation of a universal steady flow endoreversible refrigeration cycle model consisting of a constant thermal-capacity heating branch, two constant thermal-capacity cooling branches and two adiabatic branches is viewed as a production process with exergy as its output. The finite time exergoeconomic performance optimization of the refrigeration cycle is investigated by taking profit rate optimization criterion as the objective. The relations between the profit rate and the temperature ratio of working fluid, between the COP (coefficient of performance) and the temperature ratio of working fluid, as well as the optimal relation between profit rate and the COP of the cycle are derived. The focus of this paper is to search the compromised optimization between economics (profit rate) and the utilization factor (COP) for endoreversible refrigeration cycles, by searching the optimum COP at maximum profit, which is termed as the finite-time exergoeconomic performance bound. Moreover, performance analysis and optimization of the model are carried out in order to investigate the effect of cycle process on the performance of the cycles using numerical example. The results obtained herein include the performance characteristics of endoreversible Carnot, Diesel, Otto, Atkinson, Dual and Brayton refrigeration cycles.

  11. Exergoeconomic performance optimization for a steady-flow endoreversible refrigeration model including six typical cycles

    Directory of Open Access Journals (Sweden)

    Lingen Chen, Xuxian Kan, Fengrui Sun, Feng Wu

    2013-01-01

    Full Text Available The operation of a universal steady flow endoreversible refrigeration cycle model consisting of a constant thermal-capacity heating branch, two constant thermal-capacity cooling branches and two adiabatic branches is viewed as a production process with exergy as its output. The finite time exergoeconomic performance optimization of the refrigeration cycle is investigated by taking profit rate optimization criterion as the objective. The relations between the profit rate and the temperature ratio of working fluid, between the COP (coefficient of performance and the temperature ratio of working fluid, as well as the optimal relation between profit rate and the COP of the cycle are derived. The focus of this paper is to search the compromised optimization between economics (profit rate and the utilization factor (COP for endoreversible refrigeration cycles, by searching the optimum COP at maximum profit, which is termed as the finite-time exergoeconomic performance bound. Moreover, performance analysis and optimization of the model are carried out in order to investigate the effect of cycle process on the performance of the cycles using numerical example. The results obtained herein include the performance characteristics of endoreversible Carnot, Diesel, Otto, Atkinson, Dual and Brayton refrigeration cycles.

  12. Systemic low temperature signaling in Arabidopsis.

    Science.gov (United States)

    Gorsuch, Peter A; Sargeant, Alexander W; Penfield, Steven D; Quick, W Paul; Atkin, Owen K

    2010-09-01

    When leaves are exposed to low temperature, sugars accumulate and transcription factors in the C-repeat binding factor (CBF) family are expressed, which, together with CBF-independent pathways, are known to contribute to the cold acclimation process and an increase in freezing tolerance. What is not known, however, is whether expression of these cold-regulated genes can be induced systemically in response to a localized cold treatment. To address this, pre-existing, mature leaves of warm-grown Arabidopsis thaliana were exposed to a localized cold treatment (near 10 °C) whilst conjoined newly developing leaves continued only to experience warmer temperatures. In initial experiments on wild-type A. thaliana (Col-0) using real-time reverse transcription--PCR (RT-PCR) we observed that some genes--including CBF genes, certain downstream cold-responsive (COR) targets and CBF-independent transcription factors--respond to a direct 9 °C treatment of whole plants. In subsequent experiments, we found that the treatment of expanded leaves with temperatures near 10 °C can induce cold-associated genes in conjoined warm-maintained tissues. CBF1 showed a particularly strong systemic response, although CBF-independent transcription factors also responded. Moreover, the localized cold treatment of A. thaliana (C24) plants with a luciferase reporter fused to the promoter region of KIN2 indicated that in warm-maintained leaves, KIN2 might respond to a systemic signal from remote, directly cold-treated leaves. Collectively, our study provides strong evidence that the processes involved in cold acclimation are partially mediated by a signal that acts systemically. This has the potential to act as an early-warning system to enable developing leaves to cope better with the cold environment in which they are growing.

  13. Effect of heat stress on body temperature in healthy early postpartum dairy cows.

    Science.gov (United States)

    Burfeind, O; Suthar, V S; Heuwieser, W

    2012-12-01

    Measurement of body temperature is the most common method for an early diagnosis of sick cows in fresh cow protocols currently used on dairy farms. Thresholds for fever range from 39.4 °C to 39.7 °C. Several studies attempted to describe normal temperature ranges for healthy dairy cows in the early puerperium. However, the definition of a healthy cow is variable within these studies. It is challenging to determine normal temperature ranges for healthy cows because body temperature is usually included in the definition. Therefore, the objectives of this study were to identify factors that influence body temperature in healthy dairy cows early postpartum and to determine normal temperature ranges for healthy cows that calved in a moderate (temperature humidity index: 59.8 ± 3.8) and a hot period (temperature humidity index: 74.1 ± 4.4), respectively, excluding body temperature from the definition of the health status. Furthermore, the prevalence of fever was calculated for both periods separately. A subset of 17 (moderate period) and 15 cows (hot period) were used for analysis. To ensure their uterine health only cows with a serum haptoglobin concentration ≤ 1.1 g/L were included in the analysis. Therefore, body temperature could be excluded from the definition. A vaginal temperature logger that measured vaginal temperature every 10 min was inserted from Day 2 to 10 after parturition. Additionally rectal temperature was measured twice daily. Day in milk (2 to 10), period (moderate and hot), and time of day had an effect on rectal and vaginal temperature. The prevalence of fever (≥ 39.5 °C) was 7.4% and 28.1% for rectal temperature in the moderate and hot period, respectively. For vaginal temperature (07.00 to 11.00 h) it was 10% and 33%, respectively, considering the same threshold and period. This study demonstrates that body temperature in the early puerperium is influenced by several factors (day in milk, climate, time of day). Therefore, these factors

  14. The Temperature Condition of the Plate with Temperature-Dependent Thermal Conductivity and Energy Release

    Directory of Open Access Journals (Sweden)

    V. S. Zarubin

    2016-01-01

    Full Text Available The temperature state of a solid body, in addition to the conditions of its heat exchange with the environment, can greatly depend on the heat release (or heat absorption processes within the body volume. Among the possible causes of these processes should be noted such as a power release in the fuel elements of nuclear reactors, exothermic or endothermic chemical reactions in the solid body material, which respectively involve heat release or absorbtion, heat transfer of a part of the electric power in the current-carrying conductors (so-called Joule’s heat or the energy radiation penetrating into the body of a semitransparent material, etc. The volume power release characterizes an intensity of these processes.The extensive list of references to the theory of heat conductivity of solids offers solutions to problems to determine a stationary (steady over time and non-stationary temperature state of the solids (as a rule, of the canonical form, which act as the sources of volume power release. Thus, in general case, a possibility for changing power release according to the body volume and in solving the nonstationary problems also a possible dependence of this value on the time are taken into consideration.However, in real conditions the volume power release often also depends on the local temperature, and such dependence can be nonlinear. For example, with chemical reactions the intensity of heat release or absorption is in proportion to their rate, which, in turn, is sensitive to the temperature value, and a dependence on the temperature is exponential. A further factor that in such cases makes the analysis of the solid temperature state complicated, is dependence on the temperature and the thermal conductivity of this body material, especially when temperature distribution therein  is significantly non-uniform. Taking into account the influence of these factors requires the mathematical modeling methods, which allow us to build an adequate

  15. 考虑管理者风险态度因子的生产运作系统能力应急管理模型研究%Disrupting Capacity Management Model of Production Operation System by Including Decision-Maker's Risk Attitude Factor

    Institute of Scientific and Technical Information of China (English)

    包兴

    2011-01-01

    In the recent decades, many external factors (e. G. Natural disasters, terrorist attacks, and political turmoil) have constantly disrupted the normal operations of some large-scaled systems, such as power grids, communication stations and chemical plants. The system disruption can cause great losses to a society and its economy. The management begins paying attention to hedging risks of system disruptions. Current literature underestimates the potential influence of a decision maker's risk attitude ( e. G. Risk-netural, conservative or aggressive) on risk management. To provide a reasonable model to manage risks associated with the capacity disruption, we add the risk attitude of decision makers to a mathematical model.In the year of 2008, a great freezingA heavy rain hit the southern China in 2008 and, which caused the a wide-ranged collapse of power grids. When managing the disruption, we found that damaged systems need to face two important issues. First, During the disruption management, we found two interesting restricts that capacity-injured systems have to face; first, the recovery of critical capacity is a cost-expensive and multi-periods process, due to the technique of maintenance department and provision of spare parts.Second, capacity-sharing partners could support parts of capacity that is usually much cheaper than recovery; however, the sharing of capacity has limited quantity and uncertain provision. Based on these findings, a a factor is firstly constructed to map the inventory and capacity-shortage into a decision-maker's risk attitude. Second, we proposed a single-period capacity disruption management model and then extended it to a multi-period model that has a proven unique solution sequence. Finally, we present a sensitive analysis towards key parameters by using the Genetic Algorithm.A comparison is presented with the research of [ 17 ] , we find 4Four interesting managerial insights were discovered. First, aggressive or conservative of

  16. Economic impact of using nonmetallic materials in low to intermediate temperature geothermal well construction

    Energy Technology Data Exchange (ETDEWEB)

    1979-12-01

    Four appendices are included. The first covers applications of low-temperature geothermal energy including industrial processes, agricultural and related processes, district heating and cooling, and miscellaneous. The second discusses hydrogeologic factors affecting the design and construction of low-temperature geothermal wells: water quality, withdrawal rate, water depth, water temperature, basic well designs, and hydrogeologic provinces. In the third appendix, properties of metallic and nonmetallic materials are described, including: specific gravity, mechanical strength properties, resistance to physical and biological attack, thermal properties of nonmetallics, fluid flow characteristics, corrosion resistance, scaling resistance, weathering resistance of nonmetallics, and hydrolysis resistance of nonmetallics. Finally, special considerations in the design and construction of low-temperature geothermal wells using nonmetallics materials are covered. These include; drilling methods, joining methods, methods of casing and screen installation, well cementing, and well development. (MHR)

  17. Temperature, activity, and lizard life histories.

    Science.gov (United States)

    Adolph, S C; Porter, W P

    1993-08-01

    Lizard life-history characteristics vary widely among species and populations. Most authors seek adaptive or phylogenetic explanations for life-history patterns, which are usually presumed to reflect genetic differences. However, lizard life histories are often phenotypically plastic, varying in response to temperature, food availability, and other environmental factors. Despite the importance of temperature to lizard ecology and physiology, its effects on life histories have received relatively little attention. We present a theoretical model predicting the proximate consequences of the thermal environment for lizard life histories. Temperature, by affecting activity times, can cause variation in annual survival rate and fecundity, leading to a negative correlation between survival rate and fecundity among populations in different thermal environments. Thus, physiological and evolutionary models predict the same qualitative pattern of life-history variation in lizards. We tested our model with published life-history data from field studies of the lizard Sceloporus undulatus, using climate and geographical data to reconstruct estimated annual activity seasons. Among populations, annual activity times were negatively correlated with annual survival rate and positively correlated with annual fecundity. Proximate effects of temperature may confound comparative analyses of lizard life-history variation and should be included in future evolutionary models.

  18. Core body temperature in obesity.

    Science.gov (United States)

    Heikens, Marc J; Gorbach, Alexander M; Eden, Henry S; Savastano, David M; Chen, Kong Y; Skarulis, Monica C; Yanovski, Jack A

    2011-05-01

    A lower core body temperature set point has been suggested to be a factor that could potentially predispose humans to develop obesity. We tested the hypothesis that obese individuals have lower core temperatures than those in normal-weight individuals. In study 1, nonobese [body mass index (BMI; in kg/m(2)) temperature-sensing capsules, and we measured core temperatures continuously for 24 h. In study 2, normal-weight (BMI of 18-25) and obese subjects swallowed temperature-sensing capsules to measure core temperatures continuously for ≥48 h and kept activity logs. We constructed daily, 24-h core temperature profiles for analysis. Mean (±SE) daily core body temperature did not differ significantly between the 35 nonobese and 46 obese subjects (36.92 ± 0.03°C compared with 36.89 ± 0.03°C; P = 0.44). Core temperature 24-h profiles did not differ significantly between 11 normal-weight and 19 obese subjects (P = 0.274). Women had a mean core body temperature ≈0.23°C greater than that of men (36.99 ± 0.03°C compared with 36.76 ± 0.03°C; P body temperature. It may be necessary to study individuals with function-altering mutations in core temperature-regulating genes to determine whether differences in the core body temperature set point affect the regulation of human body weight. These trials were registered at clinicaltrials.gov as NCT00428987 and NCT00266500.

  19. Non-equilibrium of high-temperature nitrogen and oxygen

    Science.gov (United States)

    Kunc, J. A.; Soon, W. H.

    1988-01-01

    A stationary colloidal-radiative model for determination of production of electrons, excited atoms, and spectral line intensities in high-temperature atomic N and O is presented. The populations of several atomic levels and partition functions, and the intensities of several lines, are calculated in a wide range of conditions. Transport of radiation is included by coupling the rate equations for production of the electrons and excited atoms with the Holstein escape factors which are not constant, but depend on plasma conditions.

  20. Low Temperature Induced Conformation Changes of Aminoacylase

    Institute of Scientific and Technical Information of China (English)

    谢强; 孟凡国; 周海梦

    2004-01-01

    Control of aggregation, by lowering temperature and protein concentrations, can enhance the extent of successful refolding. The low temperature has been used in protein folding studies, as undesired aggregations often occur at higher temperatures. Therefore, it is very important to study the effects of low temperature on the native enzyme to help understand the factors that affect the structure of the proteins. In this paper, aminoacylase was studied at different temperatures by measuring enzyme activity, fluorescence emission spectra, and ultraviolet difference spectra. The results show that aminoacylase conformation changes as the temperature changes, becoming more compact at low temperatures, and having more secondary structural content. However, the activity is very low at low temperature, and totally diminishes at 4℃. Aminoacylase tends therefore to be more condense, with less residues exposed and low enzyme activities at low temperature. This observation might explain the self-protection of organisms under conditions of extreme temperature.

  1. Comparison of two air temperature gridding methods over complex terrain in China

    Science.gov (United States)

    Shi, Guoping; Sun, Zhian; Qiu, Xinfa; Zeng, Yan; Chen, Peng; Liu, Changjie

    2017-08-01

    This paper evaluates the monthly mean air temperature over complex terrain in China determined using two methods: Australian National University spline and GridMet_Climate_Temperature (grid meteorological and climatic temperature (GMCT)) models. It is found that the macroscopic patterns of the temperature distributions by the two methods are very similar. The comparison of modelled temperatures with observations from 40 verification stations shows that both methods have the same value of total mean absolute bias errors (MABE) of 0.43 °C. Since the observational data used are from meteorological observational stations which are located on horizontal flat and open areas, these evaluation results only represent those on the flat open areas. In order to evaluate the effects of topographical factors on the temperature, a concept of relief amplitude is defined. The temperatures are grouped according to range of the relief amplitudes, and variation of temperature with relief amplitudes is worked out. It is found that the temperature difference between the two models varies significantly with relief amplitudes. The averaged maximum difference can be as large as 12 °C in January when the relief amplitude is greater than 700 m. The reasons for the temperature difference are investigated, and they are due to the effects of topographical slopes and aspects. One model (GMCT) includes these effects while the other does not. The evaluation results demonstrate that it is necessary to include the effects of topographical factors in the model simulation in order to produce realistic temperature distributions in the complex terrain areas. The distributions of temperature on the northern and southern slopes are determined using the GMCT model, and the results show that the temperatures on the southern slopes are clearly greater than those of the northern slopes, especially in winter. These results can be used as a guide for the reasonable and sustainable utilization of heat

  2. Improving Planck calibration by including frequency-dependent relativistic corrections

    CERN Document Server

    Quartin, Miguel

    2015-01-01

    The Planck satellite detectors are calibrated in the 2015 release using the "orbital dipole", which is the time-dependent dipole generated by the Doppler effect due to the motion of the satellite around the Sun. Such an effect has also relativistic time-dependent corrections of relative magnitude 10^(-3), due to coupling with the "solar dipole" (the motion of the Sun compared to the CMB rest frame), which are included in the data calibration by the Planck collaboration. We point out that such corrections are subject to a frequency-dependent multiplicative factor. This factor differs from unity especially at the highest frequencies, relevant for the HFI instrument. Since currently Planck calibration errors are dominated by systematics, to the point that polarization data is currently unreliable at large scales, such a correction can in principle be highly relevant for future data releases.

  3. Improving Planck calibration by including frequency-dependent relativistic corrections

    Science.gov (United States)

    Quartin, Miguel; Notari, Alessio

    2015-09-01

    The Planck satellite detectors are calibrated in the 2015 release using the "orbital dipole", which is the time-dependent dipole generated by the Doppler effect due to the motion of the satellite around the Sun. Such an effect has also relativistic time-dependent corrections of relative magnitude 10-3, due to coupling with the "solar dipole" (the motion of the Sun compared to the CMB rest frame), which are included in the data calibration by the Planck collaboration. We point out that such corrections are subject to a frequency-dependent multiplicative factor. This factor differs from unity especially at the highest frequencies, relevant for the HFI instrument. Since currently Planck calibration errors are dominated by systematics, to the point that polarization data is currently unreliable at large scales, such a correction can in principle be highly relevant for future data releases.

  4. Modelling global fresh surface water temperature

    NARCIS (Netherlands)

    Beek, L.P.H. van; Eikelboom, T.; Vliet, M.T.H. van; Bierkens, M.F.P.

    2011-01-01

    Temperature directly determines a range of water physical properties including vapour pressure, surface tension, density and viscosity, and the solubility of oxygen and other gases. Indirectly water temperature acts as a strong control on fresh water biogeochemistry, influencing sediment

  5. Modelling global fresh surface water temperature

    NARCIS (Netherlands)

    Beek, L.P.H. van; Eikelboom, T.; Vliet, M.T.H. van; Bierkens, M.F.P.

    2011-01-01

    Temperature directly determines a range of water physical properties including vapour pressure, surface tension, density and viscosity, and the solubility of oxygen and other gases. Indirectly water temperature acts as a strong control on fresh water biogeochemistry, influencing sediment concentrati

  6. Temperature Gradient in Hall Thrusters

    Energy Technology Data Exchange (ETDEWEB)

    D. Staack; Y. Raitses; N.J. Fisch

    2003-11-24

    Plasma potentials and electron temperatures were deduced from emissive and cold floating probe measurements in a 2 kW Hall thruster, operated in the discharge voltage range of 200-400 V. An almost linear dependence of the electron temperature on the plasma potential was observed in the acceleration region of the thruster both inside and outside the thruster. This result calls into question whether secondary electron emission from the ceramic channel walls plays a significant role in electron energy balance. The proportionality factor between the axial electron temperature gradient and the electric field is significantly smaller than might be expected by models employing Ohmic heating of electrons.

  7. Temperature Monitoring and Perioperative Thermoregulation

    Science.gov (United States)

    Sessler, Daniel I.

    2008-01-01

    Most clinically available thermometers accurately report the temperature of whatever tissue is being measured. The difficulty is that no reliably core-temperature measuring sites are completely non-invasive and easy to use — especially in patients not having general anesthesia. Nonetheless, temperature can be reliably measured in most patients. Body temperature should be measured in patients having general anesthesia exceeding 30 minutes in duration, and in patients having major operations under neuraxial anesthesia. Core body temperature is normally tightly regulated. All general anesthetics produce a profound dose-dependent reduction in the core temperature triggering cold defenses including arterio-venous shunt vasoconstriction and shivering. Anesthetic-induced impairment of normal thermoregulatory control, and the resulting core-to-peripheral redistribution of body heat, is the primary cause of hypothermia in most patients. Neuraxial anesthesia also impairs thermoregulatory control, although to a lesser extant than general anesthesia. Prolonged epidural analgesia is associated with hyperthermia whose cause remains unknown. PMID:18648241

  8. 关于影响高分子材料玻璃化转变温度因素的教学分析%Teaching Analysis of the Affecting Factors to Glass Transition Temperatures of Polymer Materials

    Institute of Scientific and Technical Information of China (English)

    赵亚奇; 冯巧; 杜玲枝; 丁明洁

    2012-01-01

    从《高分子物理》考试试题实例出发,抓住聚合物材料的“结构决定性能,并最终决定用途”这条主线,详迷了链结构因素(主链和取代基)和分子间作用力对聚合物玻璃化转变温度(瓦)的影响,并结合不同高分子材料的用途进行分析,使学生真切了解到材料结构与性能及用途之间的关系。这种理论联系实际的案例教学法有利于加深学生对高分子材料的感性认识,引发学生学习的广泛兴趣,促使教师进行自我教育和提高业务水平,从而取得良好的教学效果。%Properties of polymer materials are determined by their structures, and finally affect their applications. Catching this primary point and combining applications of different polymer materials, effects of chain structure (including main chain and substitute group) on glass transition temperatures are detailedly discussed from the test question in the examination of Polymer Physics. Relationship between structure and property is deeply comprehended by the students. The case teaching method makes the students' perceptual knowledge of polymer materials and learning interests to be improved. Furthermore,the teachers' self-education and professional skills are promoted. And then the teaching effect will be much better than the normal method.

  9. Progress of studies on the responses of the key physiological processes including photosynthese in Ulva prolifera O. F. Müller to environmental factors%浒苔光合作用等关键生理过程对环境因子响应途径的研究进展

    Institute of Scientific and Technical Information of China (English)

    王广策; 唐学玺; 何培民; 孙松; 高山; 郇丽; 王辉

    2016-01-01

    近年来,以浒苔(Ulva prolifera O. F. Müller)为原因种的绿潮在我国黄海海域持续爆发,已成为主要的生态灾害,国家对此高度重视,国际科学期刊上也发表了一系列研究论文,内容包括绿潮成因种浒苔的溯源和浒苔生理过程、繁殖途径及其对非生物胁迫因子的响应等,这些研究对认识绿潮的爆发机制有重要意义。为全面了解浒苔的研究状况,本文综述了近年来关于浒苔繁殖方式和途径、光合作用及其对非生物胁迫因子的响应的研究进展,同时对关键生物学过程进行了科学描述。%Recently, green tides mainly caused by Ulva prolifera O. F. Müller occurred frequently in the Yellow Sea of China and have become one of primary ecological disasters. Increasing attention has been paid to the event by the government of China. As a result, a large number of papers including tracking the algal origin of the green tides, physiological process and reproduction methods in U. prolifera and the responses of this alage to aboitic stresses have been published in the international journals. Those studies play an important role in un-derstanding the formation mechanism of green tides. In this paper, we reviewed the different methods of repro-duction in U. prolifera, photosynthesis, its responses to aboitic stresses and description of the key biological process.

  10. Ultrahigh-Temperature Ceramics

    Science.gov (United States)

    Johnson, Sylvia M.; Ellerby, Donald T.; Beckman, Sarah E.; Irby, Edward; Gasch, Matthew J.; Gusman, Michael I.

    2007-01-01

    Ultrahigh temperature ceramics (UHTCs) are a class of materials that include the diborides of metals such as hafnium and zirconium. The materials are of interest to NASA for their potential utility as sharp leading edges for hypersonic vehicles. Such an application requires that the materials be capable of operating at temperatures, often in excess of 2,000 C. UHTCs are highly refractory and have high thermal conductivity, an advantage for this application. UHTCs are potentially applicable for other high-temperature processing applications, such as crucibles for molten-metal processing and high-temperature electrodes. UHTCs were first studied in the 1960 s by the U.S. Air Force. NASA s Ames Research Center concentrated on developing materials in the HfB2/SiC family for a leading-edge application. The work focused on developing a process to make uniform monolithic (2-phase) materials, and on the testing and design of these materials. Figure 1 shows arc-jet models made from UHTC materials fabricated at Ames. Figure 2 shows a cone being tested in the arc-jet. Other variations of these materials being investigated elsewhere include zirconium based materials and fiber-reinforced composites. Current UHTC work at Ames covers four broad topics: monoliths, coatings, composites, and processing. The goals include improving the fracture toughness, thermal conductivity and oxidation resistance of monolithic UHTCs and developing oxidation-resistant UHTC coatings for thermal-protection-system substrates through novel coating methods. As part of this effort, researchers are exploring compositions and processing changes that have yielded improvements in properties. Computational materials science and nanotechnology are being explored as approaches to reduce materials development time and improve and tailor properties.

  11. 水热因子对克氏针茅草原土壤呼吸及其土壤温度敏感性的影响%The influence of hydrothermal factors on soil respiration and soil temperature sensi-tivity of Stipa krylovii steppe,Inner Mongolia,China

    Institute of Scientific and Technical Information of China (English)

    谷蕊; 潮洛濛; 张立欣; 苏力德; 万志强; 闫玉龙; 陈雅丽; 高清竹

    2015-01-01

    .Soil respiration is an important component of the carbon cycle on the steppe and the main source of soil carbon losses.In this study,typical grassland dominated by S .krylovii,located in Mao-deng Ranch,Xilinhaote,Inner Mongolia was selected as the study area.An open top type growth chamber was used to simulate the response of soil respiration to temperature and precipitation from 2011 to 2013.The Auto-mated Soil CO2 Flux System (LI-8100,LI-COR,NE)was used to observe the soil respiration in the study area during the growing season (May to September).Air temperature,soil temperature and soil moisture were measured using the EM50 Data Collection System (Decagon Devices,Inc.,NE,USA).Soil samples were col-lected,soil nutrients and microbial numbers were determined and correlation analysis used to explore associa-tions between soil respiration rate and environmental factors.Soil respiration was significantly affected by air temperature and soil water content (P <0.01).Under warm and warm-moist conditions respectively soil respi-ration rates were 2.60 μmol/(m2 ·s)and 1.96 μmol/(m2 ·s)(2012)and 3.38 μmol/(m2 ·s)and 2.09 μmol/(m2 ·s)(2013 );differences between years were significant (P <0.05 ).Increased air temperature and de-creased soil water content both inhibited soil respiration.During the 2013 growing season additional environ-mental factors including soil organic carbon,total nitrogen and soil microbial mass may also have affected soil respiration.The Q10 temperature coefficient was significantly increased by warm-moist conditions.It was con-cluded that soil respiration is mainly influenced by hydrothermal conditions;increased air temperature and re-duced soil moisture content inhibit soil respiration.The relationship between environment factors and soil res-piration on the Inner Mongolian steppe is complex and requires further research.

  12. Analysis of Temperature Distributions in Nighttime Inversions

    Science.gov (United States)

    Telyak, Oksana; Krasouski, Aliaksandr; Svetashev, Alexander; Turishev, Leonid; Barodka, Siarhei

    2015-04-01

    Adequate prediction of temperature inversion in the atmospheric boundary layer is one of prerequisites for successful forecasting of meteorological parameters and severe weather events. Examples include surface air temperature and precipitation forecasting as well as prediction of fog, frosts and smog with hazardous levels of atmospheric pollution. At the same time, reliable forecasting of temperature inversions remains an unsolved problem. For prediction of nighttime inversions over some specific territory, it is important to study characteristic features of local circulation cells formation and to properly take local factors into account to develop custom modeling techniques for operational use. The present study aims to investigate and analyze vertical temperature distributions in tropospheric inversions (isotherms) over the territory of Belarus. We study several specific cases of formation, evolution and decay of deep nighttime temperature inversions in Belarus by means of mesoscale numerical simulations with WRF model, considering basic mechanisms of isothermal and inverse temperature layers formation in the troposphere and impact of these layers on local circulation cells. Our primary goal is to assess the feasibility of advance prediction of inversions formation with WRF. Modeling results reveal that all cases under consideration have characteristic features of radiative inversions (e.g., their formation times, development phases, inversion intensities, etc). Regions of "blocking" layers formation are extensive and often spread over the entire territory of Belarus. Inversions decay starts from the lowermost (near surface) layer (altitudes of 5 to 50 m). In all cases, one can observe formation of temperature gradients that substantially differ from the basic inversion gradient, i.e. the layer splits into smaller layers, each having a different temperature stratification (isothermal, adiabatic, etc). As opposed to various empirical techniques as well as

  13. Ionic liquids, electrolyte solutions including the ionic liquids, and energy storage devices including the ionic liquids

    Energy Technology Data Exchange (ETDEWEB)

    Gering, Kevin L.; Harrup, Mason K.; Rollins, Harry W.

    2015-12-08

    An ionic liquid including a phosphazene compound that has a plurality of phosphorus-nitrogen units and at least one pendant group bonded to each phosphorus atom of the plurality of phosphorus-nitrogen units. One pendant group of the at least one pendant group comprises a positively charged pendant group. Additional embodiments of ionic liquids are disclosed, as are electrolyte solutions and energy storage devices including the embodiments of the ionic liquid.

  14. Multistructural variational transition state theory: kinetics of the hydrogen abstraction from carbon-2 of 2-methyl-1-propanol by hydroperoxyl radical including all structures and torsional anharmonicity.

    Science.gov (United States)

    Xu, Xuefei; Yu, Tao; Papajak, Ewa; Truhlar, Donald G

    2012-11-01

    We calculated the forward and reverse rate constants of the hydrogen abstraction reaction from carbon-2 of 2-methyl-1-propanol by hydroperoxyl radical over the temperature range 250-2400 K by using multistructural canonical variational transition state theory (MS-CVT) including both multiple-structure and torsional potential anharmonicity effects by the multistructural torsional anharmonicity (MS-T) method. In these calculations, multidimensional tunneling (MT) probabilities used to compute the tunneling transmission coefficients were evaluated by the small-curvature tunneling (SCT) approximation. Comparison with the rate constants obtained by the single-structural harmonic oscillator (SS-HO) approximation shows that multistructural anharmonicity increases the forward rate constants for all temperatures, but the reverse rate constants are reduced for temperatures lower than 430 K and increased for higher temperatures. The neglect of multistructural torsional anharmonicity would lead to errors of factors of 1.5, 8.8, and 13 at 300, 1000, and 2400 K, respectively, for the forward reaction, and would lead to errors of factors of 0.76, 3.0, and 6.0, respectively, at these temperatures for the reverse reaction.

  15. Optimising the composition of natural moulding sands including thermal aspects

    Directory of Open Access Journals (Sweden)

    Jerzy St. Kowalski

    2011-04-01

    Full Text Available The paper discusses the problem of the choice of the moulding sand mixture composition in terms of the sand behaviour in contact withmolten metal. Studies of high-temperature phenomena make assessment of the sand composition applicability under real operatingconditions possible, thus leading to the elimination of sand-originating casting defects. The research was conducted on selected moulding materials included in the composition of traditional moulding sand mixtures without the addition of carbon. The effect of moulding sand composition and moisture content on the linear dilatation and stress-induced allotropic changes of quartz was examined. The analysis of these phenomena was based on 3D charts and maps generated from data collected during the tests.

  16. Global model including multistep ionizations in helium plasmas

    Science.gov (United States)

    Oh, Seung-Ju; Lee, Hyo-Chang; Chung, Chin-Wook

    2016-12-01

    Particle and power balance equations including stepwise ionizations are derived and solved in helium plasmas. In the balance equations, two metastable states (21S1 in singlet and 23S1 triplet) are considered and the followings are obtained. The plasma density linearly increases and the electron temperature is relatively in a constant value against the absorbed power. It is also found that the contribution to multi-step ionization with respect to the single-step ionization is in the range of 8%-23%, as the gas pressure increases from 10 mTorr to 100 mTorr. Compared to the results in the argon plasma, there is little variation in the collisional energy loss per electron-ion pair created (ɛc) with absorbed power and gas pressure due to the small collision cross section and higher inelastic collision threshold energy.

  17. Simulation Research on Self-compensation Technique of Temperature-induced Scale Factor Error for Optical Voltage Sensor%光学电压互感器变比温度误差自补偿技术仿真研究

    Institute of Scientific and Technical Information of China (English)

    李传生; 荆平; 张朝阳; 孙海江

    2014-01-01

    变比温度误差是限制光学电压互感器实用化的主要因素。分析Faraday旋光器及BGO晶体线性电光系数的温度相关性对互感器变比的影响机制,提出一种基于Faraday旋光角温度特性及其对互感器变比的影响自动补偿BGO晶体电光系数温度相关性的变比误差自补偿方法。仿真结果表明:在–40+70℃,对于温度系数为0.04/℃的Faraday旋光器,当常温下Faraday旋光角在41.643.2时,变比误差在0.5%以内;当常温下Faraday旋光角为42.3时,互感器的变比误差最小,约为0.3%。要使补偿后互感器的变比误差小于0.2%,Faraday 旋光角的温度系数应小于0.03/℃。该方法为光学电压互感器变比温度误差的抑制提供新途径。%The temperature-induced scale factor error is a primary constraint on the practical applications of the optical voltage sensor (OVS). The effect mechanism of the temperature-dependent rotation angle of the Faraday rotator and the temperature-dependent linear electro-optic coefficient of the BGO crystal on the scale factor is analyzed. The method utilizing the temperature dependence of the Faraday rotator and its effect on the scale factor to self-compensate the scale factor error of the temperature-dependent electro-optic coefficient of the BGO crystal is presented. Over the temperature range from –40℃ to +70℃, if the temperature coefficient of the Faraday rotation angle is 0.04/℃, the rotation angle at room temperature must be set between 41.6 and 43.2 to ensure the scale factor error of the sensor to be within0.5%. In addition, when the rotation angle at room temperature is 42.3, the scale factor error obtains the minimum 0.3%. If the scale factor error of the sensor is required to be controlled within0.2% after compensation, the temperature coefficient of the Faraday rotation angle must be less than 0.03/℃. The proposed method offers a potential

  18. Factor analysis

    CERN Document Server

    Gorsuch, Richard L

    2013-01-01

    Comprehensive and comprehensible, this classic covers the basic and advanced topics essential for using factor analysis as a scientific tool in psychology, education, sociology, and related areas. Emphasizing the usefulness of the techniques, it presents sufficient mathematical background for understanding and sufficient discussion of applications for effective use. This includes not only theory but also the empirical evaluations of the importance of mathematical distinctions for applied scientific analysis.

  19. Low temperature friction force microscopy

    Science.gov (United States)

    Dunckle, Christopher Gregory

    The application of friction force techniques within atomic force microscopy (AFM) allows for direct measurements of friction forces at a sliding, single-asperity interface. The temperature dependence of such single-asperity contacts provides key insight into the comparative importance of dissipative mechanisms that result in dry sliding friction. A variable temperature (VT), ultrahigh vacuum (UHV) AFM was used with an interface consisting of a diamond coated AFM tip and diamond-like carbon sample in a nominal sample temperature range of 90 to 275K. The results show that the coefficient of kinetic friction, mu k, has a linear dependence that is monotonically increasing with temperature varying from 0.28 to 0.38. To analyze this data it is necessary to correlate the sample temperature to the interface temperature. A detailed thermal model shows that the sample temperature measured by a macroscopic device can be very different from the temperature at the contact point. Temperature gradients intrinsic to the design of VT, UHV AFMs result in extreme, non-equilibrium conditions with heat fluxes on the order of gigawatts per squared meter through the interface, which produce a discontinuous step in the temperature profile due to thermal boundary impedance. The conclusion from this model is that measurements acquired by VT, UHV AFM, including those presented in this thesis, do not provide meaningful data on the temperature dependence of friction for single-asperities. Plans for future work developing an isothermal AFM capable of the same measurements without the introduction of temperature gradients are described. The experimental results and thermal analysis described in this thesis have been published in the Journal of Applied Physics, "Temperature dependence of single-asperity friction for a diamond on diamondlike carbon interface", J. App. Phys., 107(11):114903, 2010.

  20. Prediction of human core body temperature using non-invasive measurement methods

    Science.gov (United States)

    Niedermann, Reto; Wyss, Eva; Annaheim, Simon; Psikuta, Agnes; Davey, Sarah; Rossi, René Michel

    2014-01-01

    The measurement of core body temperature is an efficient method for monitoring heat stress amongst workers in hot conditions. However, invasive measurement of core body temperature (e.g. rectal, intestinal, oesophageal temperature) is impractical for such applications. Therefore, the aim of this study was to define relevant non-invasive measures to predict core body temperature under various conditions. We conducted two human subject studies with different experimental protocols, different environmental temperatures (10 °C, 30 °C) and different subjects. In both studies the same non-invasive measurement methods (skin temperature, skin heat flux, heart rate) were applied. A principle component analysis was conducted to extract independent factors, which were then used in a linear regression model. We identified six parameters (three skin temperatures, two skin heat fluxes and heart rate), which were included for the calculation of two factors. The predictive value of these factors for core body temperature was evaluated by a multiple regression analysis. The calculated root mean square deviation (rmsd) was in the range from 0.28 °C to 0.34 °C for all environmental conditions. These errors are similar to previous models using non-invasive measures to predict core body temperature. The results from this study illustrate that multiple physiological parameters (e.g. skin temperature and skin heat fluxes) are needed to predict core body temperature. In addition, the physiological measurements chosen in this study and the algorithm defined in this work are potentially applicable as real-time core body temperature monitoring to assess health risk in broad range of working conditions.

  1. Cytokine expression of microscopic colitis including interleukin-17.

    Science.gov (United States)

    Park, Eun-Kyoung; Park, Young Sook; Park, Dae Rim; Jung, Sung Ae; Han, Dong Soo; Jang, Byung Ik; Kim, Young Ho; Kim, Won Ho; Jo, Yun Ju; Lee, Ki Ho; Lee, Won Mi; Kim, Eun Kyung; Koo, Hae Soo

    2015-05-23

    Microscopic colitis is characterized by chronic watery diarrhea with specific pathological changes that can be diagnosed by microscopic examination. We performed immunohistochemical analysis of proinflammatory cytokines to investigate the pathogenic mechanism of microscopic colitis. This study consisted of six patients with lymphocytic colitis, six patients with collagenous colitis, and six patients with functional diarrhea but normal pathology. We performed an immunohistochemical analysis of the colonic mucosal biopsies to assess the expression of cyclo-oxygenase-2, interleukin-17, nuclear factor-κB, interferon-γ, inducible nitric oxide synthase, and tumor necrosis factor-α. We compared the quantity score of immunohistochemical staining among the groups. The microscopic colitis group showed significantly higher expression of cyclo-oxygenase-2, interleukin-17, nuclear factor-κB, and interferon-γ compared with the control group. Cytokine expression was similar between collagenous colitis and lymphocytic colitis. However, the expression of cyclo-oxygenase-2 was higher in collagenous colitis. Proinflammatory cytokines, including interleukin-17 and interferon-γ, are highly expressed in microscopic colitis. The expression of cyclo-oxygenase-2 was higher in collagenous colitis than in lymphocytic colitis. This s