WorldWideScience

Sample records for external flowsheet review

  1. Use of Flowsheet Monitoring to Perform Environmental Evaluation of Chemical Process Flowsheets

    Science.gov (United States)

    Flowsheet monitoring interfaces have been proposed to the Cape-Open Laboratories Network to enable development of applications that access to multiple parts of the flowsheet or its thermodynamic models, without interfering with the flowsheet itself. These flowsheet monitoring app...

  2. A technetium rejection flowsheet

    International Nuclear Information System (INIS)

    Baker, R.; Miles, J.H.; Roberts, P.T.

    1990-01-01

    A single contactor unit has been designed which enables Tc to be removed from a TBP/diluent stream bearing U and Pu, by means of a 5M HNO 3 wash. A Tc waste stream is produced which is virtually free from U and Pu. The flowsheet has been tested firstly with U and Tc, then with U, Pu and Tc, and finally in a highly active facility with real PWR fuel solution. About 97% of the Tc was removed from the organic phase and U and Pu levels in the Tc waste have usually been below 0.04% of those in the product stream. (author)

  3. Technetium removal: preliminary flowsheet options

    International Nuclear Information System (INIS)

    Eager, K.M.

    1995-01-01

    This document presents the results of a preliminary investigation into options for preliminary flowsheets for 99Tc removal from Hanford Site tank waste. A model is created to show the path of 99Tc through pretreatment to disposal. The Tank Waste Remediation (TWRS) flowsheet (Orme 1995) is used as a baseline. Ranges of important inputs to the model are developed, such as 99Tc inventory in the tanks and important splits through the TWRS flowsheet. Several technetium removal options are discussed along with sensitivities of the removal schemes to important model parameters

  4. Hot Experimental Facility reference flowsheet

    International Nuclear Information System (INIS)

    North, E.D.

    1982-01-01

    This paper is a useful set of background information of HEF flowsheets, although many changes have been made in the past three years. The HEF reference flowsheet is a modified high-acid PUREX flowsheet capable of operating in the coprocessing mode or with full partitioning of U and Pu. Adequate decontamination factors are provided to purify high-burnup, fast breeder-reactor fuels to levels required for recycle back to a fuel fabrication facility. Product streams are mixed U-Pu oxide and uranium oxide. No contaminated liquid wastes are intentionally discharged to the environment. All wastes are solidified and packaged for appropriate disposal. Acid and water are recovered for internal recycle. Excess water is treated and discharged from the plant stack. Several changes have been made in the reference flowsheet since that time, and these are noted briefly

  5. 78 FR 47016 - Submission for Review: Request for External Review

    Science.gov (United States)

    2013-08-02

    ... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Request for External Review AGENCY: U.S... External Review. As required by the Paperwork Reduction Act of 1995, (Pub. L. 104-13, 44 U.S.C. chapter 35... the Multi-State Plan Program (MSPP) on March 11, 2013, 78 FR 15560, which outlined an external review...

  6. Heat integrated ethanol dehydration flowsheets

    Energy Technology Data Exchange (ETDEWEB)

    Hutahaean, L.S.; Shen, W.H.; Brunt, V. Van [Univ. of South Carolina, Columbia, SC (United States)

    1995-04-01

    zA theoretical evaluation of heat-integrated heterogeneous-azeotropic ethanol-water distillation flowsheets is presented. Simulations of two column flowsheets using several different hydrocarbon entrainers reveal a region of potential heat integration and substantial reduction in operating energy. In this paper, methods for comparing hydrocarbon entrainers are shown. Two aspects of entrainers are related to operating and capital costs. The binary azeotropic composition of the entrainer-ethanol mixture is related to the energy requirements of the flowsheet. A temperature difference in the azeotrophic column is related to the size of the column and overall process staging requirements. Although the hydrophobicity of an entrainer is essential for specification of staging in the dehydration column, no substantial increase in operating energy results from an entrainer that has a higher water content. Likewise, liquid-liquid equilibria between several entrainer-ethanol-water mixtures have no substantial effect on either staging or operation. Rather, increasing the alcohol content of the entrainer-ethanol azeotrope limits its recovery in the dehydration column, and increases the recycle and reflux streams. These effects both contribute to increasing the separation energy requirements and reducing the region of potential heat integration. A cost comparison with a multieffect extractive distillation flowsheet reveals that the costs are comparable; however, the extractive distillation flowsheet is more cost effective as operating costs increase.

  7. Technical review of externalities issues. Final report

    International Nuclear Information System (INIS)

    Niemeyer, V.

    1994-12-01

    Externalities has become the catchword for a major experiment in electric utility regulation. Together with increased competition as a means for economic regulation, this experiment represents a potential revolution in how electric utilities are regulated. It is very important for utilities and policy makers to understand the technical issues and arguments driving the externality experiment. This Technical Review presents four papers covering topics in economics that may play important roles in this revolution. The four papers are: Economic Issues in the Application of Externalities to Electricity Resource Selection; Climate Change, the Marginal Cost of Carbon Dioxide Emissions and the Implications for Carbon Dioxide Emissions Adders; Positive Externalities and Benefits from Electricity; and Socioeconomic Effects of Externality Adders for Electric Utility Emissions

  8. Development of computer code SIMPSEX for simulation of FBR fuel reprocessing flowsheets: II. additional benchmarking results

    International Nuclear Information System (INIS)

    Shekhar Kumar; Koganti, S.B.

    2003-07-01

    Benchmarking and application of a computer code SIMPSEX for high plutonium FBR flowsheets was reported recently in an earlier report (IGC-234). Improvements and recompilation of the code (Version 4.01, March 2003) required re-validation with the existing benchmarks as well as additional benchmark flowsheets. Improvements in the high Pu region (Pu Aq >30 g/L) resulted in better results in the 75% Pu flowsheet benchmark. Below 30 g/L Pu Aq concentration, results were identical to those from the earlier version (SIMPSEX Version 3, code compiled in 1999). In addition, 13 published flowsheets were taken as additional benchmarks. Eleven of these flowsheets have a wide range of feed concentrations and few of them are β-γ active runs with FBR fuels having a wide distribution of burnup and Pu ratios. A published total partitioning flowsheet using externally generated U(IV) was also simulated using SIMPSEX. SIMPSEX predictions were compared with listed predictions from conventional SEPHIS, PUMA, PUNE and PUBG. SIMPSEX results were found to be comparable and better than the result from above listed codes. In addition, recently reported UREX demo results along with AMUSE simulations are also compared with SIMPSEX predictions. Results of the benchmarking SIMPSEX with these 14 benchmark flowsheets are discussed in this report. (author)

  9. External Program Reviews (2012) | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-06-24

    Jun 24, 2016 ... These final evaluations are our primary accountability mechanism in terms of the results, effectiveness, and relevance of program spending. External program reviews aim to: account to IDRC's Board of Governors for the implementation of the program prospectus; provide input into programming for learning ...

  10. Enriched uranium recovery flowsheet improvements

    International Nuclear Information System (INIS)

    Holt, D.L.

    1986-01-01

    Savannah River uses 7.5% TBP to recover and purify enriched uranium. Adequate decontamination from fission products is necessary to reduce personnel exposure and to ensure that the enriched uranium product meets specifications. Initial decontamination of the enriched uranium from the fission products is carried out in the 1A bank, 16 stages of mixer-settlers. Separation of the enriched uranium from the fission product, 95 Zr, has been adequate, but excessive solvent degradation caused by the long phase contact times in the mixer-settlers has limited the 95 Zr decontamination factor (DF). An experimental program is investigating the replacement of the current 1A bank with either centrifugal contactors or a combination of centrifugal contactors and mixer-settlers. Experimental work completed has compared laboratory-scale centrifugal contactors and mixer-settlers for 95 Zr removal efficiencies. Feed solutions spiked with actual plant solutions were used. The 95 Zr DF was significantly better in the mixer-settlers than in the centrifugal contactors. As a result of this experimental study, a hybrid equipment flowsheet has been proposed for plant use. The hybrid equipment flowsheet combines the advantages of both types of solvent extraction equipment. Centrifugal contactors would be utilized in the extraction and initial scrub sections, followed by additional scrub stages of mixer-settlers

  11. IRIS Toxicological Review of Methanol (Noncancer) (Revised External Review Draft)

    Science.gov (United States)

    EPA is seeking additional public comment and external peer review of the scientific basis supporting the human health hazard and dose-response assessment of methanol (noncancer). Teleconference Details: The public may participate in th...

  12. Flowsheet for 63Ni production

    International Nuclear Information System (INIS)

    Williams, D.F.; Knauer, J.B.; O'Kelley, G.D.; Wiggins, J.T.; Porter, C.E.

    1992-01-01

    The production of large quantities of high specific activity 63 Ni (>10Ci/g) requires both a highly enriched 62 Ni target and a long irradiation period at high neutron flux. Trace impurities in the nickel and associated target materials are also activated and account for a significant fraction of the discharged activity and essentially all of the gamma activity. While most of these undesirable activation products (mainly transition metals) can be easily removed as chloride complexes during anion exchange, chromium, present as 51 Cr, and manganese, present as 54 Mn, are exceptions and require solvent extraction of the in-cell product to achieve the desired purity. In addition to summarizing the current development and production experience, optimized flowsheets are discussed

  13. IPEEE Review of other external events of the NPP Asco

    International Nuclear Information System (INIS)

    Canadell, F.; Aleman, A.; Beltran, F.; Pifarre, D.; Hernandez, H.; Gasca, C.

    2011-01-01

    Within the process of maintaining and updating the risk analysis of the NPP Asco, results from the review of the vulnerability study of the plant against severe accidents caused by external success (Individual Plant Examination of External Events, IPEEE).

  14. Mercury Phase II Study - Mercury Behavior in Salt Processing Flowsheet

    International Nuclear Information System (INIS)

    Jain, V.; Shah, H.; Wilmarth, W. R.

    2016-01-01

    Mercury (Hg) in the Savannah River Site Liquid Waste System (LWS) originated from decades of canyon processing where it was used as a catalyst for dissolving the aluminum cladding of reactor fuel. Approximately 60 metric tons of mercury is currently present throughout the LWS. Mercury has long been a consideration in the LWS, from both hazard and processing perspectives. In February 2015, a Mercury Program Team was established at the request of the Department of Energy to develop a comprehensive action plan for long-term management and removal of mercury. Evaluation was focused in two Phases. Phase I activities assessed the Liquid Waste inventory and chemical processing behavior using a system-by-system review methodology, and determined the speciation of the different mercury forms (Hg+, Hg++, elemental Hg, organomercury, and soluble versus insoluble mercury) within the LWS. Phase II activities are building on the Phase I activities, and results of the LWS flowsheet evaluations will be summarized in three reports: Mercury Behavior in the Salt Processing Flowsheet (i.e. this report); Mercury Behavior in the Defense Waste Processing Facility (DWPF) Flowsheet; and Mercury behavior in the Tank Farm Flowsheet (Evaporator Operations). The evaluation of the mercury behavior in the salt processing flowsheet indicates, inter alia, the following: (1) In the assembled Salt Batches 7, 8 and 9 in Tank 21, the total mercury is mostly soluble with methylmercury (MHg) contributing over 50% of the total mercury. Based on the analyses of samples from 2H Evaporator feed and drop tanks (Tanks 38/43), the source of MHg in Salt Batches 7, 8 and 9 can be attributed to the 2H evaporator concentrate used in assembling the salt batches. The 2H Evaporator is used to evaporate DWPF recycle water. (2) Comparison of data between Tank 21/49, Salt Solution Feed Tank (SSFT), Decontaminated Salt Solution Hold Tank (DSSHT), and Tank 50 samples suggests that the total mercury as well as speciated

  15. Findings Brief External Review of the Ecosystem Approaches to ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    External Review of the Ecosystem Approaches to Human. Health Program ... Improved understanding of social, political, economic, and ecological interactions and .... global learning, communication among partners and others stakeholders.

  16. Low temperature dissolution flowsheet for plutonium metal

    Energy Technology Data Exchange (ETDEWEB)

    Daniel, W. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Almond, P. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Rudisill, T. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-05-01

    The H-Canyon flowsheet used to dissolve Pu metal for PuO2 production utilizes boiling HNO3. SRNL was requested to develop a complementary dissolution flowsheet at two reduced temperature ranges. The dissolution and H2 generation rates of Pu metal were investigated using a dissolving solution at ambient temperature (20-30 °C) and for an intermediate temperature of 50-60 °C. Additionally, the testing included an investigation of the dissolution rates and characterization of the off-gas generated from the ambient temperature dissolution of carbon steel cans and the nylon bags that contain the Pu metal when charged to the dissolver.

  17. Review IPEEE C.N. external event Vandellos II

    International Nuclear Information System (INIS)

    Hernandez, H.; Gasca, C.; Beltran, F.; Salvat, M.; Pifarre, D.; Canadell, F.; Aleman, A.

    2010-01-01

    Within the process of maintaining and updating the risk analysis of CN Vandellos II, results from the review of the study of vulnerability of the plant against severe accidents caused by external events (Individual Plant Examination on Extornal Events, IPEEE).

  18. Computer Aided Flowsheet Design using Group Contribution Methods

    DEFF Research Database (Denmark)

    Bommareddy, Susilpa; Eden, Mario R.; Gani, Rafiqul

    2011-01-01

    In this paper, a systematic group contribution based framework is presented for synthesis of process flowsheets from a given set of input and output specifications. Analogous to the group contribution methods developed for molecular design, the framework employs process groups to represent...... information of each flowsheet to minimize the computational load and information storage. The design variables for the selected flowsheet(s) are identified through a reverse simulation approach and are used as initial estimates for rigorous simulation to verify the feasibility and performance of the design....

  19. 33 CFR 385.22 - Independent scientific review and external peer review.

    Science.gov (United States)

    2010-07-01

    ... external peer review. 385.22 Section 385.22 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT... RESTORATION PLAN CERP Implementation Processes § 385.22 Independent scientific review and external peer review... members, shall not attempt to influence the panel's review or assign this panel any other tasks, nor...

  20. First-cycle studies of coprocessing flowsheets

    International Nuclear Information System (INIS)

    Gray, J.H.

    1981-06-01

    Selected portions of two coprocessing flowsheets developed for use at the Barnwell Nuclear Fuel Plant (BNFP) have been tested in the laboratory with uranium, plutonium, and fission products. Processing conditions and stream compositions for first cycle extraction and uranium-plutonium partitioning in an electropulse column were controlled to examine the behavior of nitric acid, uranium, plutonium, and fission products during coprocessing. The ability to adapt coprocessing technology for use in the BNFP reprocessing facility was successful for first cycle extraction and partition. The only process adjustment involved a reduction in nitric acid concentration to attain proper uranium to plutonium ratios

  1. A flowsheet for a wave power unit

    Energy Technology Data Exchange (ETDEWEB)

    Sobierajski, E.; Kasperowicz, Z.

    1984-01-01

    A flowsheet is examined for a wave power unit designed to produce electricity, for flooding or drying a coastal zone, cleaning or protecting water areas of ports from sand deposits. The unit includes a vertical cylinder attached to the sea floor with input and output water ducts and valves. The cylinder has a rod with piston that is actuated through a flexible cable by float arranged next to the cylinder. The water injected under pressure into the pressure pipe can be used directly or as an intermediate energy source.

  2. Automated process flowsheet synthesis for membrane processes using genetic algorithm: role of crossover operators

    KAUST Repository

    Shafiee, Alireza; Arab, Mobin; Lai, Zhiping; Liu, Zongwen; Abbas, Ali

    2016-01-01

    In optimization-based process flowsheet synthesis, optimization methods, including genetic algorithms (GA), are used as advantageous tools to select a high performance flowsheet by ‘screening’ large numbers of possible flowsheets. In this study, we

  3. Self-injury and externalizing pathology: a systematic literature review.

    Science.gov (United States)

    Meszaros, Gergely; Horvath, Lili Olga; Balazs, Judit

    2017-05-03

    During the last decade there is a growing scientific interest in nonsuicidal self-injury (NSSI). The aim of the current paper was to review systematically the literature with a special focus on the associations between self-injurious behaviours and externalizing psychopathology. An additional aim was to review terminology and measurements of self-injurious behaviour and the connection between self-injurious behaviours and suicide in the included publications. A systematic literature search was conducted on 31st December 2016 in five databases (PubMed, OVID Medline, OVID PsycINFO, Scopus, Web of Science) with two categories of search terms (1. nonsuicidal self-injury, non-suicidal self-injury, NSSI, self-injurious behaviour, SIB, deliberate self-harm, DSH, self-injury; 2. externalizing disorder, attention deficit hyperactivity disorder, ADHD, conduct disorder, CD, oppositional defiant disorder, OD, ODD). Finally 35 papers were included. Eleven different terms were found for describing self-injurious behaviours and 20 methods for measuring it. NSSI has the clearest definition. All the examined externalizing psychopathologies had strong associations with self-injurious behaviours according to: higher prevalence rates in externalizing groups than in control groups, higher externalizing scores on the externalizing scales of questionnaires, higher symptom severity in self-injurious groups. Eight studies investigated the relationship between suicide and self-injurious behaviours and found high overlap between the two phenomena and similar risk factors. Based on the current findings the association between externalizing psychopathology and self-injurious behaviours has been proven by the scientific literature. Similarly to other reviews on self-injurious behaviours the confusion in terminology and methodology was noticed. NSSI is suggested for use as a distinct term. Further studies should investigate the role of comorbid conditions in NSSI, especially when internalizing

  4. Group Contribution Based Process Flowsheet Synthesis, Design and Modelling

    DEFF Research Database (Denmark)

    d'Anterroches, Loïc; Gani, Rafiqul

    2005-01-01

    In a group contribution method for pure component property prediction, a molecule is described as a set of groups linked together to form a molecular structure. In the same way, for flowsheet "property" prediction, a flowsheet can be described as a set of process-groups linked together to represent...... the flowsheet structure. Just as a functional group is a collection of atoms, a process-group is a collection of operations forming an "unit" operation or a set of "unit" operations. The link between the process-groups are the streams similar to the bonds that are attachments to atoms/groups. Each process-group...... provides a contribution to the "property" of the flowsheet, which can be performance in terms of energy consumption, thereby allowing a flowsheet "property" to be calculated, once it is described by the groups. Another feature of this approach is that the process-group attachments provide automatically...

  5. Neuraxial blockade for external cephalic version: a systematic review.

    Science.gov (United States)

    Sultan, P; Carvalho, B

    2011-10-01

    The desire to decrease the number of cesarean deliveries has renewed interest in external cephalic version. The rationale for using neuraxial blockade to facilitate external cephalic version is to provide abdominal muscular relaxation and reduce patient discomfort during the procedure, so permitting successful repositioning of the fetus to a cephalic presentation. This review systematically examined the current evidence to determine the safety and efficacy of neuraxial anesthesia or analgesia when used for external cephalic version. A systematic literature review of studies that examined success rates of external cephalic version with neuraxial anesthesia was performed. Published articles written in English between 1945 and 2010 were identified using the Medline, Cochrane, EMBASE and Web of Sciences databases. Six, randomized controlled studies were identified. Neuraxial blockade significantly improved the success rate in four of these six studies. A further six non-randomized studies were identified, of which four studies with control groups found that neuraxial blockade increased the success rate of external cephalic version. Despite over 850 patients being included in the 12 studies reviewed, placental abruption was reported in only one patient with a neuraxial block, compared with two in the control groups. The incidence of non-reassuring fetal heart rate requiring cesarean delivery in the anesthesia groups was 0.44% (95% CI 0.15-1.32). Neuraxial blockade improved the likelihood of success during external cephalic version, although the dosing regimen that provides optimal conditions for successful version is unclear. Anesthetic rather than analgesic doses of local anesthetics may improve success. The findings suggest that neuraxial blockade does not compromise maternal or fetal safety during external cephalic version. Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

  6. Self-injury and externalizing pathology: a systematic literature review

    OpenAIRE

    Meszaros, Gergely; Horvath, Lili Olga; Balazs, Judit

    2017-01-01

    Background During the last decade there is a growing scientific interest in nonsuicidal self-injury (NSSI). The aim of the current paper was to review systematically the literature with a special focus on the associations between self-injurious behaviours and externalizing psychopathology. An additional aim was to review terminology and measurements of self-injurious behaviour and the connection between self-injurious behaviours and suicide in the included publications. Methods A systematic l...

  7. Flowsheet development for HTGR fuel reprocessing

    International Nuclear Information System (INIS)

    Baxter, B.; Benedict, G.E.; Zimmerman, R.D.

    1976-01-01

    Development studies to date indicate that the HTGR fuel blocks can be effectively crushed with two stages of eccentric jaw crushing, followed by a double-roll crusher, a screener and an eccentrically mounted single-roll crusher for oversize particles. Burner development results indicate successful long-term operation of both the primary and secondary fluidized-bed combustion systems can be performed with the equipment developed in this program. Aqueous separation development activities have centered on adapting known Acid-Thorex processing technology to the HTGR reprocessing task. Significant progress has been made on dissolution of burner ash, solvent extraction feed preparation, slurry transfer, solids drying and solvent extraction equipment and flowsheet requirements

  8. Flowsheet finalisation for immobilisation of SGHWR wastes

    International Nuclear Information System (INIS)

    Lee, D.J.

    1984-09-01

    This report summarises research and development work carried out during the year ended March 1983 on the programme for cementing the Winfrith Reactor (SGHWR) sludge. Further results from the characterisation programme are reported, together with data from the cementation programme. Formulations based on Ordinary Portland Cement (OPC), ground granulated blast furnace slag (BFS) and Pulverised Fuel Ash (PFA) have been tested. The results show that a blend of 90% BFS/10% OPC by weight, gives the best properties. Chemical pretreatment as a method for producing a stable waste form is discussed. A dewatering pretreatment to provide a sludge suitable for direct cementation is also outlined. A flowsheet for cementing the SGHWR sludge is proposed based on these laboratory and pilot scale studies. The major components required for the active plant are identified and provisional plant layouts are given. (author)

  9. Integrated HLW Conceptual Process Flowsheet(s) for the Crystalline Silicotitanate Process SRDF-98-04

    International Nuclear Information System (INIS)

    Jacobs, R.A.

    1998-01-01

    The Strategic Research and Development Fund (SRDF) provided funds to develop integrated conceptual flowsheets and material balances for a CST process as a potential replacement for, or second generation to, the ITP process. This task directly supports another SRDF task: Glass Form for HLW Sludge with CST, SRDF-98-01, by M. K. Andrews which seeks to further develop sludge/CST glasses that could be used if the ITP process were replaced by CST ion exchange. The objective of the proposal was to provide flowsheet support for development and evaluation of a High Level Waste Division process to replace ITP. The flowsheets would provide a conceptual integrated material balance showing the impact on the HLW division. The evaluation would incorporate information to be developed by Andrews and Harbour on CST/DWPF glass formulations and provide the bases for evaluating the economic impact of the proposed replacement process. Coincident with this study, the Salt Disposition Team began its evaluation of alternatives for disposition of the HLW salts in the SRS waste tanks. During that time, the CST IX process was selected as one of four alternatives (of eighteen Phase II alternatives) for further evaluation during Phase III

  10. Nitric acid flowsheet with late wash PHA testing

    International Nuclear Information System (INIS)

    Zamecnik, J.R.

    1993-01-01

    This Task Technical Plan outlines the activities to be conducted in the Integrated DWPF Melter System (IDMS) in ongoing support of the Defense Waste Processing Facility (DWPF) Chemical Process Cell (CPC) utilizing the Nitric Acid Flowsheet in the Sludge Receipt and Adjustment Tank (SRAT) and Precipitate Hydrolysis Aqueous (PHA) produced by the Late Wash Flowsheet. The IDMS facility is to be operated over a series of runs (2 to 4) using the Nitric Acid Flowsheet. The PHA will be produced with the Late Wash Flowsheet in the Precipitate Hydrolysis Experimental Facility (PHEF). All operating conditions shall simulate the expected DWPF operating conditions as closely as possible. The task objectives are to perform at least two IDMS runs with as many operating conditions as possible at nominal DWPF conditions. The major purposes of these runs are twofold: verify that the combined Late Wash and Nitric Acid flowsheets produce glass of acceptable quality without additional changes to process equipment, and determine the reproducibility of data from run to run. These runs at nominal conditions will be compared to previous runs made with PHA produced from the Late Wash flowsheet and with the Nitric Acid flowsheet in the SRAT (Purex 4 and Purex 5)

  11. Reprocessing flowsheet and material balance for MEU spent fuel

    International Nuclear Information System (INIS)

    Abraham, L.

    1978-10-01

    In response to nonproliferation concerns, the high-temperature gas-cooled reactor (HTGR) Fuel Recycle Development Program is investigating the processing requirements for a denatured medium-enriched uranium--thorium (MEU/Th) fuel cycle. Prior work emphasized the processing requirements for a high-enriched uranium--thorium (HEU/Th) fuel cycle. This report presents reprocessing flowsheets for an HTGR/MEU fuel recycle base case. Material balance data have been calculated for reprocessing of spent MEU and recycle fuels in the HTGR Recycle Reference Facility (HRRF). Flowsheet and mass flow effects in MEU-cycle reprocessing are discussed in comparison with prior HEU-cycle flowsheets

  12. Group Contribution Based Process Flowsheet Synthesis, Design and Modelling

    DEFF Research Database (Denmark)

    d'Anterroches, Loïc; Gani, Rafiqul

    2004-01-01

    This paper presents a process-group-contribution Method to model. simulate and synthesize a flowsheet. The process-group based representation of a flowsheet together with a process "property" model are presented. The process-group based synthesis method is developed on the basis of the computer...... aided molecular design methods and gives the ability to screen numerous process alternatives without the need to use the rigorous process simulation models. The process "property" model calculates the design targets for the generated flowsheet alternatives while a reverse modelling method (also...... developed) determines the design variables matching the target. A simple illustrative example highlighting the main features of the methodology is also presented....

  13. IRIS Toxicological Review of Trichloroacetic Acid (TCA) (External Review Draft)

    Science.gov (United States)

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Trichloroacetic acid (TCA) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  14. IRIS Toxicological Review of Trichloroethylene (TCE) (External Review Draft)

    Science.gov (United States)

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Trichloroethylene (TCE) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  15. IRIS Toxicological Review of Hydrogen Cyanide (External Review Draft)

    Science.gov (United States)

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of hydrogen cyanide and cyanide salts that will appear on the Integrated Risk Information System (IRIS) database.

  16. IRIS Toxicological Review of Tetrahydrofuran (THF) (External Review Draft)

    Science.gov (United States)

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of tetrahydrofuran (THF) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  17. External Reviews, Internal Influences: Consultations and the Undergraduate Neuroscience Curriculum

    OpenAIRE

    Wiertelak, Eric P.

    2012-01-01

    In 2007 FUN established the FUN Program and Department Consultations Service, or FUN-PDCS. Since that founding, the service has provided numerous consultation recommendations to undergraduate programs seeking assistance with external program reviews, designing and improving courses and many other programmatic needs. FUN-PDCS, like FUN, is primarily a grassroots organization and draws on the expertise of the FUN membership to aid programs in their more personalized pursuit of the FUN mission: ...

  18. FRACTIONAL CRYSTALLIZATION FLOWSHEET TESTS WITH ACTUAL TANK WASTE

    International Nuclear Information System (INIS)

    HERTING, D.L.

    2006-01-01

    Laboratory-scale flowsheet tests of the fractional crystallization process were conducted with actual tank waste samples in a hot cell at the 222-S Laboratory. The process is designed to separate medium-curie liquid waste into a low-curie stream for feeding to supplemental treatment and a high-curie stream for double-shell tank storage. Separations criteria (for Cs-137 sulfate, and sodium) were exceeded in all three of the flowsheet tests that were performed

  19. Recommendation of ruthenium source for sludge batch flowsheet studies

    Energy Technology Data Exchange (ETDEWEB)

    Woodham, W. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-09-13

    Included herein is a preliminary analysis of previously-generated data from sludge batches 7a, 7b, 8, and 9 sludge simulant and real-waste testing, performed to recommend a form of ruthenium for future sludge batch simulant testing under the nitric-formic flowsheet. Focus is given to reactions present in the Sludge Receipt and Adjustment Tank cycle, given that this cycle historically produces the most changes in chemical composition during Chemical Process Cell processing. Data is presented and analyzed for several runs performed under the nitric-formic flowsheet, with consideration given to effects on the production of hydrogen gas, nitrous oxide gas, consumption of formate, conversion of nitrite to nitrate, and the removal and recovery of mercury during processing. Additionally, a brief discussion is given to the effect of ruthenium source selection under the nitric-glycolic flowsheet. An analysis of data generated from scaled demonstration testing, sludge batch 9 qualification testing, and antifoam degradation testing under the nitric-glycolic flowsheet is presented. Experimental parameters of interest under the nitric-glycolic flowsheet include N2O production, glycolate destruction, conversion of glycolate to formate and oxalate, and the conversion of nitrite to nitrate. To date, the number of real-waste experiments that have been performed under the nitric-glycolic flowsheet is insufficient to provide a complete understanding of the effects of ruthenium source selection in simulant experiments with regard to fidelity to real-waste testing. Therefore, a determination of comparability between the two ruthenium sources as employed under the nitric-glycolic flowsheet is made based on available data in order to inform ruthenium source selection for future testing under the nitric-glycolic flowsheet.

  20. IRIS Toxicological Review of 2-Hexanone (External Review ...

    Science.gov (United States)

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 2-hexanone that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appropriately in derivation of the dose-response assessments and toxicological characterization. 2-Hexanone was nominated for IRIS assessment because of its frequent detection at sites nation-wide and its occurrence as a byproduct of certain industrial processes.

  1. IRIS Toxicological Review of Methanol (External Review Draft, 2013)

    Science.gov (United States)

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of methanol (non-cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  2. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (External Review Draft)

    Science.gov (United States)

    The IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) was released for external peer review in June 2017. EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) will conduct a peer review of the scientific basis supporting the ETB...

  3. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) (External Review Draft)

    Science.gov (United States)

    The IRIS Toxicological Review of tert-Butyl Alcohol (tert-Butanol) was released for external peer review in June 2017. EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) will conduct a peer review of the scientific basis supporting ...

  4. Subsurface barrier feasibility evaluation: External review meeting report

    International Nuclear Information System (INIS)

    Lindberg, S.L.; Rouse, J.K.

    1994-12-01

    The Westinghouse Hanford Company -- Tank Waste Remediation System Division (TWRS) Program is evaluating subsurface barrier technologies for potential use in supporting remediation of the Hanford Tank Farms for the US Department of Energy, Richland Operations Office (DOE-RL). An External Review Team (ERT) was assembled to perform an independent technical review of the work performed to-date supporting the evaluation process. A set of draft documents was forwarded to the ERT for their review, and a meeting was held August 10 through 12, 1994, to facilitate comments and resolutions. This document summarizes the meeting, the comments provided by the ERT, and the ongoing work to resolve the comments and support a pending decision by The US Department of Energy, Richland Operations Office; the Washington State Department of Ecology; and the US Environmental Protection Agency

  5. IRIS Toxicological Review of n-Butanol (External Review Draft ...

    Science.gov (United States)

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of n-butanol that will appear in the Integrated Risk Information System (IRIS) database. EPA is undertaking an Integrated Risk Information System (IRIS) health assessment for n-butanol. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment paradigm, i.e., hazard identification and dose-response evaluation. IRIS assessments are used in combination with specific situational exposure assessment information to evaluate potential public health risk associated with environmental contaminants.

  6. An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios (External Review Draft)

    Science.gov (United States)

    EPA has released an external review draft entitled, An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios(External Review Draft). The public comment period and the external peer-review workshop are separate processes that provide opportunities ...

  7. Review of retrospective dosimetry techniques for external ionising radiation exposures

    International Nuclear Information System (INIS)

    Ainsbury, E. A.; Bakhanova, E.; Barquinero, J. F.; Brai, M.; Chumak, V.; Correcher, V.; Darroudi, F.; Fattibene, P.; Gruel, G.; Guclu, I.; Horn, S.; Jaworska, A.; Kulka, U.; Lindholm, C.; Lloyd, D.; Longo, A.; Marrale, M.; Monteiro Gil, O.; Oestreicher, U.; Pajic, J.; Rakic, B.; Romm, H.; Trompier, F.; Veronese, I.; Voisin, P.; Vral, A.; Whitehouse, C. A.; Wieser, A.; Woda, C.; Wojcik, A.; Rothkamm, K.

    2011-01-01

    The current focus on networking and mutual assistance in the management of radiation accidents or incidents has demonstrated the importance of a joined-up approach in physical and biological dosimetry. To this end, the European Radiation Dosimetry Working Group 10 on 'Retrospective Dosimetry' has been set up by individuals from a wide range of disciplines across Europe. Here, established and emerging dosimetry methods are reviewed, which can be used immediately and retrospectively following external ionising radiation exposure. Endpoints and assays include dicentrics, translocations, premature chromosome condensation, micronuclei, somatic mutations, gene expression, electron paramagnetic resonance, thermoluminescence, optically stimulated luminescence, neutron activation, haematology, protein biomarkers and analytical dose reconstruction. Individual characteristics of these techniques, their limitations and potential for further development are reviewed, and their usefulness in specific exposure scenarios is discussed. Whilst no single technique fulfils the criteria of an ideal dosemeter, an integrated approach using multiple techniques tailored to the exposure scenario can cover most requirements. (authors)

  8. Nitric-glycolic flowsheet testing for maximum hydrogen generation rate

    Energy Technology Data Exchange (ETDEWEB)

    Martino, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Newell, J. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Williams, M. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-03-01

    The Defense Waste Processing Facility (DWPF) at the Savannah River Site is developing for implementation a flowsheet with a new reductant to replace formic acid. Glycolic acid has been tested over the past several years and found to effectively replace the function of formic acid in the DWPF chemical process. The nitric-glycolic flowsheet reduces mercury, significantly lowers the chemical generation of hydrogen and ammonia, allows purge reduction in the Sludge Receipt and Adjustment Tank (SRAT), stabilizes the pH and chemistry in the SRAT and the Slurry Mix Evaporator (SME), allows for effective adjustment of the SRAT/SME rheology, and is favorable with respect to melter flammability. The objective of this work was to perform DWPF Chemical Process Cell (CPC) testing at conditions that would bound the catalytic hydrogen production for the nitric-glycolic flowsheet.

  9. Review of external validity reporting in childhood obesity prevention research.

    Science.gov (United States)

    Klesges, Lisa M; Dzewaltowski, David A; Glasgow, Russell E

    2008-03-01

    The translation and dissemination of prevention intervention evidence into practice is needed to address significant public health issues such as childhood obesity. Increased attention to and reporting of external validity information in research publications would allow for better understanding of generalizability issues relevant to successful translation. To demonstrate this potential, recent reports of childhood obesity prevention interventions were evaluated on the extent to which external validity dimensions were reported. Childhood obesity prevention studies that were controlled, long-term research trials published between 1980 and 2004 that reported a behavioral target of physical activity and/or healthy eating along with at least one anthropometric outcome were identified in 2005. Studies were summarized between 2005 and 2006 using review criteria developed by Green and Glasgow in 2006. Nineteen publications met selection criteria. In general, all studies lacked full reporting on potential generalizability and dissemination elements. Median reporting over all elements was 34.5%; the mode was 0% with a range of 0% to 100%. Most infrequent were reports of setting level selection criteria and representativeness, characteristics regarding intervention staff, implementation of intervention content, costs, and program sustainability. The evidence base for future prevention interventions can be improved by enhancing the reporting of contextual and generalizability elements central to translational research. Such efforts face practical hurdles but could provide additional explanation for variability in intervention outcomes, insights into successful adaptations of interventions, and help guide policy decisions.

  10. 76 FR 67439 - External Peer Review Meeting for Draft Microbial Risk Assessment Guideline: Pathogenic...

    Science.gov (United States)

    2011-11-01

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-ORD-2011-053; FRL-9485-1] External Peer Review Meeting for... review draft does not represent EPA policy. The public may register to attend this peer review meeting as... to consider the comments from the external peer review meeting, along with public comments received...

  11. Breath analysis using external cavity diode lasers: a review

    Science.gov (United States)

    Bayrakli, Ismail

    2017-04-01

    Most techniques that are used for diagnosis and therapy of diseases are invasive. Reliable noninvasive methods are always needed for the comfort of patients. Owing to its noninvasiveness, ease of use, and easy repeatability, exhaled breath analysis is a very good candidate for this purpose. Breath analysis can be performed using different techniques, such as gas chromatography mass spectrometry (MS), proton transfer reaction-MS, and selected ion flow tube-MS. However, these devices are bulky and require complicated procedures for sample collection and preconcentration. Therefore, these are not practical for routine applications in hospitals. Laser-based techniques with small size, robustness, low cost, low response time, accuracy, precision, high sensitivity, selectivity, low detection limit, real-time, and point-of-care detection have a great potential for routine use in hospitals. In this review paper, the recent advances in the fields of external cavity lasers and breath analysis for detection of diseases are presented.

  12. Integrated Science Assessment (ISA) of Ozone and Related Photochemical Oxidants (Second External Review Draft, Sep 2011)

    Science.gov (United States)

    EPA has released the Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Second External Review Draft) for independent peer review and public review. This draft document represents a concise synthesis and evaluation of the most policy-relevant scienc...

  13. A new flowsheeting tool for flue gas treating

    NARCIS (Netherlands)

    van Elk, E. P.; Arendsen, A. R. J.; Versteeg, G. F.

    2009-01-01

    A new flowsheeting tool, specifically designed for steady-state simulation of acid gas treating processes, has been developed. The models implemented in the new tool combine all issues relevant for the design, optimization and analysis of acid gas treating processes, including post-combustion and

  14. Mixed Waste Treatment Project: Computer simulations of integrated flowsheets

    International Nuclear Information System (INIS)

    Dietsche, L.J.

    1993-12-01

    The disposal of mixed waste, that is waste containing both hazardous and radioactive components, is a challenging waste management problem of particular concern to DOE sites throughout the United States. Traditional technologies used for the destruction of hazardous wastes need to be re-evaluated for their ability to handle mixed wastes, and in some cases new technologies need to be developed. The Mixed Waste Treatment Project (MWTP) was set up by DOE's Waste Operations Program (EM30) to provide guidance on mixed waste treatment options. One of MWTP's charters is to develop flowsheets for prototype integrated mixed waste treatment facilities which can serve as models for sites developing their own treatment strategies. Evaluation of these flowsheets is being facilitated through the use of computer modelling. The objective of the flowsheet simulations is to provide mass and energy balances, product compositions, and equipment sizing (leading to cost) information. The modelled flowsheets need to be easily modified to examine how alternative technologies and varying feed streams effect the overall integrated process. One such commercially available simulation program is ASPEN PLUS. This report contains details of the Aspen Plus program

  15. External review systems for radiation oncology facilities - clinical audit versus other review systems

    International Nuclear Information System (INIS)

    Bogusz-Czerniewicz, M.

    2009-01-01

    Background: Between 1996 and 1999 project team of ExPeRT, catalogued four external review systems of health care facilities in the European Union and countries associated with EU. Aim: The aim of this paper is a/ to identify and compare currently existing external review systems for radiation oncology facilities and b/ to distinguish main differences between clinical audit and other external evaluation models and c/ to identify where those models are currently used in European Union member states. Materials and Methods: Based on the literature review and the survey conducted between January and April 2007 among representatives of 67 national societies (for diagnostic radiology, radiotherapy and nuclear medicine) in European Union member states, the analysis of existing external review systems in radiation oncology was performed. Relevant information about purpose, scope and methodology of evaluation process for those systems were surveyed. Results: The response to the questionnaire was 72%. Only a few countries did not supply any reply in spite of repeated enquiries to several recipients. Six main categories of systems aiming at measuring the quality of service management and delivery were identified: professional peer review -based schemes, hospital accreditation, accreditation in terms of ISO standards, award seeking, certification by International Standards Organization, and clinical audit. Conclusions: Though the methodology and terminology of the five main external review systems differ, a constant movement towards collaboration and convergence of those models has been observed. Due to the social, political, and economical aspects of each European country, the different audit systems have been implemented either on voluntary or mandatory basis. (author)

  16. Review on studies for external cost of nuclear power generation

    Energy Technology Data Exchange (ETDEWEB)

    Park, Byung Heung [Korea National University of Transportation, Chungju (Korea, Republic of); Ko, Won Il [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-12-15

    External cost is cost imposed on a third party when producing or consuming a good or service. Since the 1990s, the external costs of nuclear powered electricity production have been studied. Costs are a very important factor in policy decision and the external cost is considered for cost comparison on electricity production. As for nuclear fuel cycle, a chosen technology will determine the external cost. However, there has been little research on this issue. For this study, methods for external cost on nuclear power production have been surveyed and analyzed to develop an approach for evaluating external cost on nuclear fuel cycles. Before the Fukushima accident, external cost research had focused on damage costs during normal operation of a fuel cycle. However, accident cost becomes a major concern after the accident. Various considerations for external cost including accident cost have been used to different studies, and different methods have been applied corresponding to the considerations. In this study, the results of the evaluation were compared and analyzed to identify methodological applicability to the external cost estimation with nuclear fuel cycles.

  17. Review on studies for external cost of nuclear power generation

    International Nuclear Information System (INIS)

    Park, Byung Heung; Ko, Won Il

    2015-01-01

    External cost is cost imposed on a third party when producing or consuming a good or service. Since the 1990s, the external costs of nuclear powered electricity production have been studied. Costs are a very important factor in policy decision and the external cost is considered for cost comparison on electricity production. As for nuclear fuel cycle, a chosen technology will determine the external cost. However, there has been little research on this issue. For this study, methods for external cost on nuclear power production have been surveyed and analyzed to develop an approach for evaluating external cost on nuclear fuel cycles. Before the Fukushima accident, external cost research had focused on damage costs during normal operation of a fuel cycle. However, accident cost becomes a major concern after the accident. Various considerations for external cost including accident cost have been used to different studies, and different methods have been applied corresponding to the considerations. In this study, the results of the evaluation were compared and analyzed to identify methodological applicability to the external cost estimation with nuclear fuel cycles

  18. Different contributions of internal reviewers and external experts to labelling decisions on therapeutic indications in new drug reviews in Japan.

    Science.gov (United States)

    Yokota, M; Kusama, M; Matsuki, N; Ono, S

    2013-12-01

    External experts play an important role in shaping regulatory decisions in the new drug review process in the United States, Europe and Japan. No rigorous study has been performed addressing how and to what extent external experts, in contrast to internal reviewers in the agency, influence the regulatory decisions during new drug reviews. We examined their contributions in Japanese regulatory reviews in contrast to the internal reviewers, focusing on the labelling decision on therapeutic indications. With the data set of 219 new molecular entities (NMEs) approved in Japan from 2000 to 2009, we observed how proposed indications in labelling were modified in a stepwise manner during the review process and conducted multinomial logistic analysis to examine the possible mechanism behind. We found that interim assessment of indications by the internal reviewers was modified substantially by the influence of the external experts in about 20% of the 219 NMEs. Our analysis suggested that internal reviewers provided their opinion mainly based on strict review discipline, whereas external experts added flexibility and reality to their reviews. Our analysis revealed different evaluations between internal reviewers and external experts during regulatory discussions in new drug reviews and how the external panel contributes to changing internal decisions. This study provides a new and quantitative approach to better label setting by emphasizing the contributions of each stakeholder in new drug reviews, which would improve the efficiency, quality and transparency of new drug reviews to enhance public health. © 2013 John Wiley & Sons Ltd.

  19. Plutonium--uranium partitioning; alternate flowsheet Plutonium Reclamation Facility. [SEPHIS

    Energy Technology Data Exchange (ETDEWEB)

    Fort, L.A.

    1975-12-01

    The SEPHIS computer program was used to predict the transient and steady-state concentrations in a stage-wise scheme for the Pu reclamation solvent extraction system. With the aid of the computer an alternative flowsheet for Pu--U partitioning was constructed. The goal of the alternative program is to reduce Pu losses from the initial stripping column and reduce the quantity of Pu-bearing wastes from the solvent extraction system. (JSR)

  20. The ability of external immobilizers to restrict movement of the cervical spine: a systematic review

    NARCIS (Netherlands)

    Holla, M.; Huisman, J.M.; Verdonschot, N.; Goosen, J.; Hosman, A.J.; Hannink, G.

    2016-01-01

    PURPOSE: To review the ability of various types of external immobilizers to restrict cervical spine movement. METHODS: With a systematical review of original scientific articles, data on range of motion, type of used external immobilization device and risk of bias were extracted. The described

  1. The ability of external immobilizers to restrict movement of the cervical spine: a systematic review

    NARCIS (Netherlands)

    Holla, M.; Huisman, J.M.; Verdonschot, Nicolaas Jacobus Joseph; Goosen, J.; Hosman, A.J.; Hannink, G.

    2016-01-01

    Purpose To review the ability of various types of external immobilizers to restrict cervical spine movement. Methods With a systematical review of original scientific articles, data on range of motion, type of used external immobilization device and risk of bias were extracted. The described

  2. Dissolution flowsheet for high flux isotope reactor fuel

    Energy Technology Data Exchange (ETDEWEB)

    Foster, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-09-27

    As part of the Spent Nuclear Fuel (SNF) processing campaign, H-Canyon is planning to begin dissolving High Flux Isotope Reactor (HFIR) fuel in late FY17 or early FY18. Each HFIR fuel core contains inner and outer fuel elements which were fabricated from uranium oxide (U3O8) dispersed in a continuous Al phase using traditional powder metallurgy techniques. Fuels fabricated in this manner, like other SNF’s processed in H-Canyon, dissolve by the same general mechanisms with similar gas generation rates and the production of H2. The HFIR fuel cores will be dissolved and the recovered U will be down-blended into low-enriched U. HFIR fuel was previously processed in H-Canyon using a unique insert in both the 6.1D and 6.4D dissolvers. Multiple cores will be charged to the same dissolver solution maximizing the concentration of dissolved Al. The objective of this study was to identify flowsheet conditions through literature review and laboratory experimentation to safely and efficiently dissolve the HFIR fuel in H-Canyon. Laboratory-scale experiments were performed to evaluate the dissolution of HFIR fuel using both Al 1100 and Al 6061 T6 alloy coupons. The Al 1100 alloy was considered a representative surrogate which provided an upper bound on the generation of flammable (i.e., H2) gas during the dissolution process. The dissolution of the Al 6061 T6 alloy proceeded at a slower rate than the Al 1100 alloy and was used to verify that the target Al concentration in solution could be achieved for the selected Hg concentration. Mass spectrometry and Raman spectroscopy were used to provide continuous monitoring of the concentration of H2 and other permanent gases in the dissolution offgas allowing the development of H2 generation rate profiles. The H2 generation rates were subsequently used to evaluate if a full HFIR core could be dissolved in an H-Canyon dissolver without exceeding 60% of the

  3. 78 FR 70598 - Submission for Review: Request for External Review (3206-NEW); Model Notice of Final Internal...

    Science.gov (United States)

    2013-11-26

    ... notice to enrollees about the result of any final internal adverse benefit determination, their external... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Request for External Review (3206-NEW); Model Notice of Final Internal Adverse Benefit Determination and Case Intake Form AGENCY: U.S. Office of...

  4. Book Review: EU External Relations Law: Text, Cases and Materials

    Directory of Open Access Journals (Sweden)

    Graham Butler

    2014-06-01

    Full Text Available This latest textbook contributing to the field of EU external relations law is unique in that it is the first such book in the post-Treaty of Lisbon environment to take a wide-angled look on as many aspects of the growing area as it continues to develop within the legal parameters as set by the Treaties, and it is suitably placed to become the core text for teaching this expanding EU policy field. In their book, EU External Relations Law: Text, Cases and Materials, Van Vooren and Wessel seek to fill the gap in up-to-date literature from a legal standpoint in the field of external relations of the EU, with a book that is suitable for delivery as a core textbook for students of all levels. Their analysis covering fifteen long chapters offers the reader a comprehensive insight into the world of EU external relations law, and allows for a thoroughly better understanding of all the encapsulated issues that are at play.

  5. Technology development in support of the TWRS process flowsheet. Revision 1

    International Nuclear Information System (INIS)

    Washenfelder, D.J.

    1995-01-01

    The Tank Waste Remediation System is to treat and dispose of Hanford's Single-Shell and Double-Shell Tank Waste. The TWRS Process Flowsheet, (WHC-SD-WM-TI-613 Rev. 1) described a flowsheet based on a large number of assumptions and engineering judgements that require verification or further definition through process and technology development activities. This document takes off from the TWRS Process Flowsheet to identify and prioritize tasks that should be completed to strengthen the technical foundation for the flowsheet

  6. IPEEE review of external events of the Asco I nuclear plant

    International Nuclear Information System (INIS)

    Aleman, A.; Canadell, F.; Beltran, F.; Pifarre, D.; Hernandez, H.; Gasca, C.

    2012-01-01

    During the risk analysis update of Asco NPP (2010), it has been carried out a review of the vulnerabilities against severe accidents caused by external events (individual Plant Examination of external Events, IPEEE). The assessment has includent analysis of accidents in industrial and military facilities nearby and transportation accidents (i.e., rail, road and aircraft impact) release of hazardous materials on site, external flooding, turbine missiles and strong winds. (Author)

  7. Prediction models for successful external cephalic version: a systematic review.

    Science.gov (United States)

    Velzel, Joost; de Hundt, Marcella; Mulder, Frederique M; Molkenboer, Jan F M; Van der Post, Joris A M; Mol, Ben W; Kok, Marjolein

    2015-12-01

    To provide an overview of existing prediction models for successful ECV, and to assess their quality, development and performance. We searched MEDLINE, EMBASE and the Cochrane Library to identify all articles reporting on prediction models for successful ECV published from inception to January 2015. We extracted information on study design, sample size, model-building strategies and validation. We evaluated the phases of model development and summarized their performance in terms of discrimination, calibration and clinical usefulness. We collected different predictor variables together with their defined significance, in order to identify important predictor variables for successful ECV. We identified eight articles reporting on seven prediction models. All models were subjected to internal validation. Only one model was also validated in an external cohort. Two prediction models had a low overall risk of bias, of which only one showed promising predictive performance at internal validation. This model also completed the phase of external validation. For none of the models their impact on clinical practice was evaluated. The most important predictor variables for successful ECV described in the selected articles were parity, placental location, breech engagement and the fetal head being palpable. One model was assessed using discrimination and calibration using internal (AUC 0.71) and external validation (AUC 0.64), while two other models were assessed with discrimination and calibration, respectively. We found one prediction model for breech presentation that was validated in an external cohort and had acceptable predictive performance. This model should be used to council women considering ECV. Copyright © 2015. Published by Elsevier Ireland Ltd.

  8. Multisystemic Therapy for Child Non-Externalizing Psychological and Health Problems: A Preliminary Review

    Science.gov (United States)

    Pane, Heather T.; White, Rachel S.; Nadorff, Michael R.; Grills-Taquechel, Amie; Stanley, Melinda A.

    2013-01-01

    Multisystemic therapy (MST) is effective for decreasing or preventing delinquency and other externalizing behaviors and increasing prosocial or adaptive behaviors. The purpose of this project was to review the literature examining the efficacy of MST for other child psychological and health problems reflecting non-externalizing behaviors,…

  9. Preliminary perspectives gaines from individual plant examination of external events (IPEEE) seismic and fire submittal review

    International Nuclear Information System (INIS)

    Chen, J.T.; Connell, E.; Chokshi, N.

    1997-01-01

    As a result of the U.S. Nuclear Regulatory Commission (USNRC) initiated Individual plant Examination of External Events (IPEEE) program, every operating nuclear power reactor in the United States has performed an assessment of severe accident due to external events. This paper provides a summary of the preliminary insights gained through the review of 24 IPEEE submittals

  10. Flowsheets and source terms for radioactive waste projections

    International Nuclear Information System (INIS)

    Forsberg, C.W.

    1985-03-01

    Flowsheets and source terms used to generate radioactive waste projections in the Integrated Data Base (IDB) Program are given. Volumes of each waste type generated per unit product throughput have been determined for the following facilities: uranium mining, UF 6 conversion, uranium enrichment, fuel fabrication, boiling-water reactors (BWRs), pressurized-water reactors (PWRs), and fuel reprocessing. Source terms for DOE/defense wastes have been developed. Expected wastes from typical decommissioning operations for each facility type have been determined. All wastes are also characterized by isotopic composition at time of generation and by general chemical composition. 70 references, 21 figures, 53 tables

  11. Integrated Science Assessment (ISA) for Carbon Monoxide (Second External Review Draft, Sep 2009)

    Science.gov (United States)

    EPA announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes was made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of t...

  12. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (First External Review Draft, Sep 2007)

    Science.gov (United States)

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluatio...

  13. Antimony Trioxide (ATO) - Summary of External Peer Review and Public Comments and Disposition

    Science.gov (United States)

    This document summarizes the public and external peer review comments that the EPA’s Office of Pollution Prevention and Toxics (OPPT) received for the draft work plan risk assessment for Antimony Trioxide (ATO).

  14. Development of the high-level waste high-temperature melter feed preparation flowsheet for vitrification process testing

    International Nuclear Information System (INIS)

    Seymour, R.G.

    1995-01-01

    High-level waste (HLW) feed preparation flowsheet development was initiated in fiscal year (FY) 1994 to evaluate alternative flowsheets for preparing melter feed for high-temperature melter (HTM) vitrification testing. Three flowsheets were proposed that might lead to increased processing capacity relative to the Hanford Waste Vitrification Plant (HWVP) and that were flexible enough to use with other HLW melter technologies. This document describes the decision path that led to the selection of flowsheets to be tested in the FY 1994 small-scale HTM tests. Feed preparation flowsheet development for the HLW HTM was based on the feed preparation flowsheet that was developed for the HWVP. This approach allowed the HLW program to build upon the extensive feed preparation flowsheet database developed under the HWVP Project. Primary adjustments to the HWVP flowsheet were to the acid adjustment and glass component additions. Developmental background regarding the individual features of the HLW feed preparation flowsheets is provided. Applicability of the HWVP flowsheet features to the new HLW vitrification mission is discussed. The proposed flowsheets were tested at the laboratory-scale at Pacific Northwest Laboratory. Based on the results of this testing and previously established criteria, a reductant-based flowsheet using glycolic acid and a nitric acid-based flowsheet were selected for the FY 1994 small-scale HTM testing

  15. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) (External Review Draft)

    Science.gov (United States)

    The IRIS Toxicological Review of Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) was released for external peer review in September 2016. The EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) will conduct a peer review of the scientific basis suppor...

  16. Tank SY-102 remediation project: Flowsheet and conceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    Yarbro, S.L.; Punjak, W.A.; Schreiber, S.B.; Dunn, S.L.; Jarvinen, G.D.; Marsh, S.F.; Pope, N.G.; Agnew, S.; Birnbaum, E.R.; Thomas, K.W.; Ortic, E.A.

    1994-01-01

    The US Department of Energy established the Tank Waste Remediation System (TWRS) to safely manage and dispose of radioactive waste stored in underground tanks on the Hanford Site. A major program in TWRS is pretreatment which was established to process the waste prior to disposal. Pretreatment is needed to resolve tank safety issues and to separate wastes into high-level and low-level fractions for subsequent immobilization and disposal. There is a fixed inventory of actinides and fission products in the tank which must be prepared for disposal. By segregating the actinides and fission products from the bulk of the waste, the tank`s contents can be effectively managed. Due to the high public visibility and environmental sensitivity of this problem, real progress and demonstrated efforts toward addressing it must begin as soon as possible. As a part of this program, personnel at the Los Alamos National Laboratory (LANL) have developed and demonstrated a flowsheet to remediate tank SY-102 which is located in the 200 West Area and contains high-level radioactive waste. This report documents the results of the flowsheet demonstrations performed with simulated, but radioactive, wastes using an existing glovebox line at the Los Alamos Plutonium Facility. The tank waste was characterized using both a tank history approach and an exhaustive evaluation of the available core sample analyses. This report also presents a conceptual design complete with a working material flow model, a major equipment list, and cost estimates.

  17. Tank SY-102 remediation project: Flowsheet and conceptual design report

    International Nuclear Information System (INIS)

    Yarbro, S.L.; Punjak, W.A.; Schreiber, S.B.; Dunn, S.L.; Jarvinen, G.D.; Marsh, S.F.; Pope, N.G.; Agnew, S.; Birnbaum, E.R.; Thomas, K.W.; Ortic, E.A.

    1994-01-01

    The US Department of Energy established the Tank Waste Remediation System (TWRS) to safely manage and dispose of radioactive waste stored in underground tanks on the Hanford Site. A major program in TWRS is pretreatment which was established to process the waste prior to disposal. Pretreatment is needed to resolve tank safety issues and to separate wastes into high-level and low-level fractions for subsequent immobilization and disposal. There is a fixed inventory of actinides and fission products in the tank which must be prepared for disposal. By segregating the actinides and fission products from the bulk of the waste, the tank's contents can be effectively managed. Due to the high public visibility and environmental sensitivity of this problem, real progress and demonstrated efforts toward addressing it must begin as soon as possible. As a part of this program, personnel at the Los Alamos National Laboratory (LANL) have developed and demonstrated a flowsheet to remediate tank SY-102 which is located in the 200 West Area and contains high-level radioactive waste. This report documents the results of the flowsheet demonstrations performed with simulated, but radioactive, wastes using an existing glovebox line at the Los Alamos Plutonium Facility. The tank waste was characterized using both a tank history approach and an exhaustive evaluation of the available core sample analyses. This report also presents a conceptual design complete with a working material flow model, a major equipment list, and cost estimates

  18. Preliminary evaluation of Am/Cm melter feed preparation process upset recovery flowsheets

    International Nuclear Information System (INIS)

    Stone, M.E.

    2000-01-01

    This document summarizes the results from the development of flowsheets to recover from credible processing errors specified in TTR 99-MNSS/SE-006. The proposed flowsheets were developed in laboratory scale equipment and will be utilized with minor modifications for full scale demonstrations in the Am/Cm Pilot Facility

  19. Sludge batch 9 follow-on actual-waste testing for the nitric-glycolic flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    Martino, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Newell, J. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Crawford, C. L. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Pareizs, J. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Williams, M. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-03-23

    An actual-waste Sludge Batch 9 qualification run with the nitric-glycolic flowsheet (SC-18) was performed in FY16. In order to supplement the knowledge base for the nitric-glycolic flowsheet, additional testing was performed on the product slurries, condensates, and intermediate samples from run SC-18.

  20. Two decades of external peer review of cancer care in general hospitals; the Dutch experience.

    Science.gov (United States)

    Kilsdonk, Melvin J; Siesling, Sabine; Otter, Rene; van Harten, Wim H

    2016-03-01

    External peer review was introduced in general hospitals in the Netherlands in 1994 to assess and improve the multidisciplinary team approach in cancer care. This paper aims to explore the value, perceived impact, and (future) role of external peer review in cancer care. Semistructured interviews were held with clinicians, oncology nurses, and managers from fifteen general hospitals that participated in three rounds of peer review over a period of 16 years. Interviewees reflected on the goals and expectations, experiences, perceived impact, and future role of external peer review. Transcriptions of the interviews were coded to discover recurrent themes. Improving clinical care and organization were the main motives for participation. Positive impact was perceived on multiple aspects of care such as shared responsibilities, internal prioritization of cancer care, improved communication, and a clear structure and position of cancer care within general hospitals. Establishing a direct relationship between the external peer review and organizational or clinical impact proved to be difficult. Criticism was raised on the content of the program being too theoretical and organization-focussed after three rounds. According to most stakeholders, external peer review can improve multidisciplinary team work in cancer care; however, the acceptance is threatened by a perceived disbalance between effort and visible clinical impact. Leaner and more clinically focused programs are needed to keep repeated peer reviews challenging and worthwhile. © 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

  1. The development and testing of the new flowsheets for the plutonium purification of the Purex process

    Energy Technology Data Exchange (ETDEWEB)

    Bugrov, K.V.; Korotaev, V.G.; Korchenkin, K.K.; Logunov, M.V.; Ludin, S.A.; Mashkin, A.N.; Melentev, A.B.; Samarina, N.S. [FSUE ' PAMayak' , Lenin st., 35, Ozersk 456780 (Russian Federation)

    2016-07-01

    In order to improve the extraction flowsheet of RT-1 Plant two versions of plutonium purification unit flowsheet were developed: a flowsheet with stabilization of Pu(IV)-Np(IV) valence pair and Pu, Np co-recovery, and a flowsheet with stabilization of Pu(IV)-Np(V) valence pair and Pu recovery. The task related to stabilization of the valence pair of the target components in the required state was solved with the use of reactants already applied at RT-1 Plant, namely, hydrogen peroxide, hydrazine nitrate and catalyst (Fe). Both flowsheets were adapted for the plant purification facility with minimum modifications of the equipment, and passed the full scale industrial testing. As a result of this work, reduction in volume and salt content of the raffinate was achieved. (authors)

  2. Internal versus External Control of Reinforcement: A Review of the Locus of Control Construct

    Science.gov (United States)

    Kormanik, Martin B.; Rocco, Tonette S.

    2009-01-01

    One aspect of personality, perceptions of internal versus external control of reinforcement, shifts under conditions of change. This review of the literature examines the relationship between planned organizational change and locus of control. The review includes literature from the disciplines of clinical and social psychology, adult development,…

  3. Using internal and external reviewers can help to optimise neonatal mortality and morbidity conferences.

    Science.gov (United States)

    Assaad, Michael-Andrew; Janvier, Annie; Lapointe, Anie

    2018-02-01

    This study determined whether there was a difference in the conclusions reached by neonatologists in morbidity and mortality conferences based on their level of involvement in a case. All neonatal deaths occurring between August 2014 and September 2015 at the neonatal intensive care unit of Sainte-Justine Hospital, Montreal, Quebec, Canada, were reviewed by internal physicians involved in the case and external physicians who were not. The reviewers were asked to identify positive and negative clinical practice items and provide written recommendations. These were classified into eight categories and compared for each case. During the study, 55 patients died leading to 110 reviews and a total of 590 positive and negative items. Most items were in the communication (25.2%), ethical decision-making (16.7%) and clinical management (14.8%) categories. Both the internal and external reviewers were in agreement 48.5% of the time for positive items and 44.8% for negative items. There were 242 written recommendations, which differed significantly among the internal and external reviewers. Reviews of neonatal deaths by two independent reviewers, internal physicians and external physicians, led to different positive and negative practice items and recommendations. This could allow for a richer discussion and improve recommendations for patient care. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  4. Method for innovative synthesis-design of chemical process flowsheets

    DEFF Research Database (Denmark)

    Kumar Tula, Anjan; Gani, Rafiqul

    Chemical process synthesis-design involve the identification of the processing route to reach a desired product from a specified set of raw materials, design of the operations involved in the processing route, the calculations of utility requirements, the calculations of waste and emission...... to the surrounding and many more. Different methods (knowledge-based [1], mathematical programming [2], hybrid, etc.) have been proposed and are also currently employed to solve these synthesis-design problems. D’ Anterroches [3] proposed a group contribution based approach to solve the synthesis-design problem...... of chemical processes, where, chemical process flowsheets could be synthesized in the same way as atoms or groups of atoms are synthesized to form molecules in computer aided molecular design (CAMD) techniques [4]. That, from a library of building blocks (functional process-groups) and a set of rules to join...

  5. Mode of delivery after successful external cephalic version: a systematic review and meta-analysis.

    Science.gov (United States)

    de Hundt, Marcella; Velzel, Joost; de Groot, Christianne J; Mol, Ben W; Kok, Marjolein

    2014-06-01

    To assess the mode of delivery in women after a successful external cephalic version by performing a systematic review and meta-analysis. We searched MEDLINE, Embase, ClinicalTrials.gov, Cumulative Index to Nursing and Allied Health Literature, and the Cochrane Library for studies reporting on the mode of delivery in women after successful external cephalic version at term and women with a spontaneous cephalic-presenting fetus. Two reviewers independently selected studies, extracted data, and assessed study quality. The association between mode of delivery and successful external cephalic version was expressed as a common odds ratio with a 95% confidence interval (CI). We identified three cohort studies and eight case-control studies, reporting on 46,641 women. The average cesarean delivery rate for women with a successful external cephalic version was 21%. Women after successful external cephalic version were at increased risk for cesarean delivery for dystocia (odds ratio [OR] 2.2, 95% CI 1.6-3.0), cesarean delivery for fetal distress (OR 2.2, 95% CI 1.6-2.9), and instrumental vaginal delivery (OR 1.4, 95% CI 1.1-1.7). Women who have had a successful external cephalic version for breech presentation are at increased risk for cesarean delivery and instrumental vaginal delivery as compared with women with a spontaneous cephalic presentation. Nevertheless, with a number needed to treat of three, external cephalic version still remains a very efficient procedure to prevent a cesarean delivery.

  6. Acute external otitis as debut of acute myeloid leukemia - A case and review of the literature.

    Science.gov (United States)

    Slengerik-Hansen, Joachim; Ovesen, Therese

    2018-03-01

    Acute leukemia is a well known childhood cancer. The relation between leukemia and otological symptoms has long been established but is highly rare as a debut symptom of leukemia. External otitis is a common condition affecting many children, and most cases are successively treated with topical medicine. Here we present a child with acute external otitis later shown to be the debut symptom of acute myeloid leukemia, to our knowledge the first specific case described. We have reviewed the literature to find red flags for suspicion of severe disease in case of acute external otitis. Copyright © 2018 Elsevier B.V. All rights reserved.

  7. IACUC evaluation and external scientific review. IACUC Overstepping its Bounds

    Energy Technology Data Exchange (ETDEWEB)

    Poston, Ted M.; Thrall, Karla D.; Penner, Jocelyn D.

    2010-08-30

    I was asked to submit a response to the Protocol Review forum for the journal LabAnimal by Dr. Jerald Silverman. This forum request views and opinions on issues that are faced by research animal welfare committees. The particular issue is: Dr. John Smith, a distinguished investigator at Great Eastern University, had spent his career searching for a treatment for hearing loss. After 20 years of research, he developed a drug that potentially could improve auditory function after damage to the inner ear. The drug was administered by injection into the middle ear with the use of a fine needle inserted through the eardrum. Smith submitted a protocol to the IACUC to conduct a small study on cats, proposing to treat one group of animals with the drug and another with saline, to determine if it prevented the changes in the anatomy of the inner ear that normally occur with aging.

  8. Effects of external stress on biodegradable orthopedic materials: A review

    Directory of Open Access Journals (Sweden)

    Xuan Li

    2016-09-01

    Full Text Available Biodegradable orthopedic materials (BOMs are used in rehabilitation and reconstruction of fractured tissues. The response of BOMs to the combined action of physiological stress and corrosion is an important issue in vivo since stress-assisted degradation and cracking are common. Although the degradation behavior and kinetics of BOMs have been investigated under static conditions, stress effects can be very serious and even fatal in the dynamic physiological environment. Since stress is unavoidable in biomedical applications of BOMs, recent work has focused on the evaluation and prediction of the properties of BOMs under stress in corrosive media. This article reviews recent progress in this important area focusing on biodegradable metals, polymers, and ceramics.

  9. Impact of scaling on the nitric-glycolic acid flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, D. [Savannah River Site (SRS), Aiken, SC (United States)

    2016-02-01

    Savannah River Remediation (SRR) is considering using glycolic acid as a replacement for formic acid in Sludge Receipt and Adjustment Tank (SRAT) processing in the Defense Waste Processing Facility (DWPF). Catalytic decomposition of formic acid is responsible for the generation of hydrogen, a potentially flammable gas, during processing. To prevent the formation of a flammable mixture in the offgas, an air purge is used to dilute the hydrogen concentration below the 60% of the Composite Lower Flammability Limit (CLFL). The offgas is continuously monitored for hydrogen using Gas Chromatographs (GCs). Since formic acid is much more volatile and toxic than glycolic acid, a formic acid spill would lead to the release of much larger quantities to the environment. Switching from formic acid to glycolic acid is expected to eliminate the hydrogen flammability hazard leading to lower air purges, thus downgrading of Safety Significant GCs to Process Support GCs, and minimizing the consequence of a glycolic acid tank leak in DWPF. Overall this leads to a reduction in process operation costs and an increase in safety margin. Experiments were completed at three different scales to demonstrate that the nitric-glycolic acid flowsheet scales from the 4-L lab scale to the 22-L bench scale and 220-L engineering scale. Ten process demonstrations of the sludge-only flowsheet for SRAT and Slurry Mix Evaporator (SME) cycles were performed using Sludge Batch 8 (SB8)-Tank 40 simulant. No Actinide Removal Process (ARP) product or strip effluent was added during the runs. Six experiments were completed at the 4-L scale, two experiments were completed at the 22-L scale, and two experiments were completed at the 220-L scale. Experiments completed at the 4-L scale (100 and 110% acid stoichiometry) were repeated at the 22-L and 220-L scale for scale comparisons.

  10. Comparison of Marginal Bone Loss Between Implants with Internal and External Connections: A Systematic Review.

    Science.gov (United States)

    Palacios-Garzón, Natalia; Mauri-Obradors, Elisabeth; Roselló-LLabrés, Xavier; Estrugo-Devesa, Albert; Jané-Salas, Enric; López-López, José

    The objective of this systematic review was to compare the loss of marginal bone between implants with internal and external connections by analyzing results reported in studies published after 2010. A literature search in MEDLINE with the keywords "dental implant connections, external internal implant connection, bone loss implant designs, internal and external connection implant studies in humans" was conducted. Clinical trials on human beings, comparing both connections and published in English, from 2010 to 2016 were selected. Their methodologic quality was assessed using the Jadad scale. From the initial search, 415 articles were obtained; 32 were chosen as potentially relevant based on their titles and abstracts. Among them, only 10 finally met the inclusion criteria. A total of 1,523 patients with 3,965 implants were analyzed. Six out of 10 studies observed that internal connections showed significantly less bone loss compared with external connections. The remaining four articles did not find statistically significant differences between the two connections. According to this systematic review and considering its limitation due to the degree of heterogeneity between the included studies, both internal and external connections present high survival rates. To assess whether marginal bone loss differs significantly between the two connections, more homogenous clinical studies are needed with identical implant characteristics, larger samples, and longer follow-up periods. Studies included in this review and characterized by long-term follow-ups showed that the external connection is a reliable connection on a long-term basis.

  11. Review of common accidents in external beam radiotherapy

    International Nuclear Information System (INIS)

    Ombogo, C.M

    2015-02-01

    This work covers patients protection in Radiotherapy which is a multi step procedure that is complex. Any error in any step has an effect on the patient and therefore the entire process requires attention to details in order to achieve patients protection. This project reviews eight case studies involving accidents that occurred during the process of therapy delivery. Professionalism in case one and two was not practiced in that in case one medical physicist failed to calculate decay data instead relied on incorrect decay graph thus giving wrong dose. While in case two a wrong TPS was approved following a formal written procedure due to new technology. In case three and seven there was a software malfunction due to uniformed choice of TPS and in case four a computer file was not updated in the TPS while in eight the failure is inter look system led to patients recieving high dose than was prescribed. Calibration in case five and six was due to wrong actions in both repairs and interpretation of treatment time than the overdose to patient. The lessen learnt seeks to act as a checklist for ensuring patient protection in radiotherapy and prevention of future accidents. (au)

  12. External review and validation of the Swedish national inpatient register

    Directory of Open Access Journals (Sweden)

    Kim Jeong-Lim

    2011-06-01

    Full Text Available Abstract Background The Swedish National Inpatient Register (IPR, also called the Hospital Discharge Register, is a principal source of data for numerous research projects. The IPR is part of the National Patient Register. The Swedish IPR was launched in 1964 (psychiatric diagnoses from 1973 but complete coverage did not begin until 1987. Currently, more than 99% of all somatic (including surgery and psychiatric hospital discharges are registered in the IPR. A previous validation of the IPR by the National Board of Health and Welfare showed that 85-95% of all diagnoses in the IPR are valid. The current paper describes the history, structure, coverage and quality of the Swedish IPR. Methods and results In January 2010, we searched the medical databases, Medline and HighWire, using the search algorithm "validat* (inpatient or hospital discharge Sweden". We also contacted 218 members of the Swedish Society of Epidemiology and an additional 201 medical researchers to identify papers that had validated the IPR. In total, 132 papers were reviewed. The positive predictive value (PPV was found to differ between diagnoses in the IPR, but is generally 85-95%. Conclusions In conclusion, the validity of the Swedish IPR is high for many but not all diagnoses. The long follow-up makes the register particularly suitable for large-scale population-based research, but for certain research areas the use of other health registers, such as the Swedish Cancer Register, may be more suitable.

  13. Dissolution Flowsheet for High Flux Isotope Reactor Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Daniel, W. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Rudisill, T. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); O' Rourke, P. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Karay, N. S [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-09-27

    As part of the Spent Nuclear Fuel (SNF) processing campaign, H-Canyon is planning to begin dissolving High Flux Isotope Reactor (HFIR) fuel in late FY17 or early FY18. Each HFIR fuel core contains inner and outer fuel elements which were fabricated from uranium oxide (U3O8) dispersed in a continuous Al phase using traditional powder metallurgy techniques. Fuels fabricated in this manner, like other SNF’s processed in H-Canyon, dissolve by the same general mechanisms with similar gas generation rates and the production of H2. The HFIR fuel cores will be dissolved and the recovered U will be down-blended into low-enriched U. HFIR fuel was previously processed in H-Canyon using a unique insert in both the 6.1D and 6.4D dissolvers. Multiple cores will be charged to the same dissolver solution maximizing the concentration of dissolved Al. The objective of this study was to identify flowsheet conditions through literature review and laboratory experimentation to safely and efficiently dissolve the HFIR fuel in H-Canyon. Laboratory-scale experiments were performed to evaluate the dissolution of HFIR fuel using both Al 1100 and Al 6061 T6 alloy coupons. The Al 1100 alloy was considered a representative surrogate which provided an upper bound on the generation of flammable (i.e., H2) gas during the dissolution process. The dissolution of the Al 6061 T6 alloy proceeded at a slower rate than the Al 1100 alloy, and was used to verify that the target Al concentration in solution could be achieved for the selected Hg concentration. Mass spectrometry and Raman spectroscopy were used to provide continuous monitoring of the concentration of H2 and other permanent gases in the dissolution offgas, allowing the development of H2 generation rate profiles. The H2 generation rates were subsequently used to evaluate if a full HFIR core could be dissolved in an H-Canyon dissolver without exceeding 60% of the

  14. Effects of external focus of attention on balance: a short review.

    Science.gov (United States)

    Park, Sun Hee; Yi, Chae Woo; Shin, Ju Yong; Ryu, Young Uk

    2015-12-01

    [Purpose] The present study reviewed studies that examined the effects of attentional focus on balance. [Methods] Keywords such as "attentional", "focus", and "balance" were used to find relevant research papers in PubMed (www.ncbi.nlm.nih.gov/pubmed). Forty-five papers were found, and 18 of them were used for this study, excluding review papers and papers irrelevant to the topic of this study. [Results] Among the papers used for the review, the number of papers in which external focus produced effective outcomes was 15 (83.3%). The number of papers in which both external and internal focus produced effective outcomes was 2 (11.1%). The number of paper in which no instruction about attentional focus was effective was 1 (5.5%), and the number of papers in which internal focus was effective was zero. [Conclusion] This short review suggests clinical implications about how physical therapists can use attentional focus for balance rehabilitation of patients. Instructions about external focus of attention can generally be useful as a method to improve posture and balance control. Furthermore, the present reviews indicates that external focus of attention would be more useful in a rehabilitation stage in which the difficulty level of balance performance is gradually increased.

  15. 76 FR 55384 - External Peer Review Meeting for the Draft Guidance of Applying Quantitative Data To Develop Data...

    Science.gov (United States)

    2011-09-07

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA/100/J-11/001; FRL-9460-1] External Peer Review Meeting for... attend this peer review meeting as observers. Time will be set aside for observers to give brief oral... the draft document, EPA intends to consider the comments from the external peer review meeting along...

  16. Why are Religiousness and Spirituality Associated with Externalizing Psychopathology? A Literature Review.

    Science.gov (United States)

    Holmes, Christopher; Kim-Spoon, Jungmeen

    2016-03-01

    This review explores the relation of religiousness and spirituality with externalizing psychopathology in adolescence given the heightened externalizing psychopathology during this developmental period. Utilizing a developmental psychopathology framework, previous literature is reviewed focusing on the diversity of pathways from religiousness and spirituality to externalizing psychopathology at multiple levels of analysis. Moreover, the pathways considered include both intraindividual factors (e.g., self-control, monitoring, delay discounting and time orientation, and neurobiological regulatory systems) and ecological factors (e.g., intergenerational transmission, parent-child relationships, and community relationships). These pathways are explored in light of theoretical viewpoints including social control theory, divine interaction theory, and the religious ecology model. Limitations of extant work are examined, including measurement and design issues, exploration of potential negative effects of religiousness and spirituality, and bias toward Western religions. Finally, future directions of research and clinical implications are discussed.

  17. Review of the Oconee-3 probabilistic risk assessment: external events, core damage frequency. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Hanan, N.A.; Ilberg, D.; Xue, D.; Youngblood, R.; Reed, J.W.; McCann, M.; Talwani, T.; Wreathall, J.; Kurth, P.D.; Bandyopadhyay, K.

    1986-03-01

    A review of the Oconee-3 Probabilistic Risk Assessment (OPRA) was conducted with the broad objective of evaluating qualitatively and quantitatively (as much as possible) the OPRA assessment of the important sequences that are ''externally'' generated and lead to core damage. The review included a technical assessment of the assumptions and methods used in the OPRA within its stated objective and with the limited information available. Within this scope, BNL performed a detailed reevaluation of the accident sequences generated by internal floods and earthquakes and a less detailed review (in some cases a scoping review) for the accident sequences generated by fires, tornadoes, external floods, and aircraft impact. 12 refs., 24 figs., 31 tabs.

  18. Review of the Oconee-3 probabilistic risk assessment: external events, core damage frequency. Volume 2

    International Nuclear Information System (INIS)

    Hanan, N.A.; Ilberg, D.; Xue, D.

    1986-03-01

    A review of the Oconee-3 Probabilistic Risk Assessment (OPRA) was conducted with the broad objective of evaluating qualitatively and quantitatively (as much as possible) the OPRA assessment of the important sequences that are ''externally'' generated and lead to core damage. The review included a technical assessment of the assumptions and methods used in the OPRA within its stated objective and with the limited information available. Within this scope, BNL performed a detailed reevaluation of the accident sequences generated by internal floods and earthquakes and a less detailed review (in some cases a scoping review) for the accident sequences generated by fires, tornadoes, external floods, and aircraft impact. 12 refs., 24 figs., 31 tabs

  19. Development of COMPAS, computer aided process flowsheet design and analysis system of nuclear fuel reprocessing

    International Nuclear Information System (INIS)

    Homma, Shunji; Sakamoto, Susumu; Takanashi, Mitsuhiro; Nammo, Akihiko; Satoh, Yoshihiro; Soejima, Takayuki; Koga, Jiro; Matsumoto, Shiro

    1995-01-01

    A computer aided process flowsheet design and analysis system, COMPAS has been developed in order to carry out the flowsheet calculation on the process flow diagram of nuclear fuel reprocessing. All of equipments, such as dissolver, mixer-settler, and so on, in the process flowsheet diagram are graphically visualized as icon on a bitmap display of UNIX workstation. Drawing of a flowsheet can be carried out easily by the mouse operation. Not only a published numerical simulation code but also a user's original one can be used on the COMPAS. Specifications of the equipment and the concentration of components in the stream displayed as tables can be edited by a computer user. Results of calculation can be also displayed graphically. Two examples show that the COMPAS is applicable to decide operating conditions of Purex process and to analyze extraction behavior in a mixer-settler extractor. (author)

  20. Application of structured flowsheets to global evaluation of tank waste processing alternatives

    International Nuclear Information System (INIS)

    Jansen, G.; Knutson, B.J.; Niccoli, L.G.; Frank, D.D.

    1994-01-01

    Remediation of the Hanford waste tanks requires integration of chemical technologies and evaluation of alternatives from the perspective of the overall Hanford cleanup purpose. The use of Design/IDEF (R) logic to connect chemical process functions to the overall cleanup mission in the Hanford Strategic Analysis (HSA) and to Aspen Plus (R) process models can show the effect of each process step on global performance measures such as safety, cost, and public perception. This hybrid of chemical process analysis and systems engineering produces structured material balance flowsheets at any level of process aggregation within the HSA. Connectivity and consistent process and stream nomenclature are automatically transferred between detailed process models, the HSA top purpose, and the global material balance flowsheet evaluation. Applications to separation processes is demonstrated for a generic Truex-Sludge Wash flowsheet with many process options and for the aggregation of a Clean Option flowsheet from a detailed chemical process level to a global evaluation level

  1. Flowsheet model for the electrochemical treatment of liquid radioactive wastes. Final report

    International Nuclear Information System (INIS)

    Hobbs, D.T.; Prasad, S.; Farell, A.E.; Weidner, J.W.; White, R.E.

    1995-01-01

    The objective of this report is to describe the modeling and optimization procedure for the electrochemical removal of nitrates and nitrites from low level radioactive wastes. The simulation is carried out in SPEEDUP trademark, which is a state of the art flowsheet modeling package. The flowsheet model will provide a better understanding of the process and aid in the scale-up of the system. For example, the flowsheet model has shown that the electrochemical cell must be operated in batch mode to achieve 95 percent destruction. The flowsheet model is detailed in this report along with a systematic description of the batch optimization of the electrochemical cell. Results from two batch runs and one optimization run are also presented

  2. Report on the flowsheet model for the electrochemical treatment of liquid radioactive wastes

    International Nuclear Information System (INIS)

    Hobbs, D.T.

    1995-01-01

    The objective of this report is to describe the modeling and optimization procedure for the electrochemical removal of nitrates and nitrites from low level radioactive wastes. The simulation is carried out in SPEEDUP trademark, which is a state of the art flowsheet modeling package. The flowsheet model will provide a better understanding of the process and aid in the scale-up of the system. For example, the flowsheet model has shown that the electrochemical cell must be operated in batch mode to achieve 95% destruction. The present status of the flowsheet model is detailed in this report along with a systematic description of the batch optimization of the electrochemical cell. Results from two batch runs and one optimization run are also presented

  3. Mode of delivery after successful external cephalic version: a systematic review and meta-analysis

    NARCIS (Netherlands)

    de Hundt, Marcella; Velzel, Joost; de Groot, Christianne J.; Mol, Ben W.; Kok, Marjolein

    2014-01-01

    To assess the mode of delivery in women after a successful external cephalic version by performing a systematic review and meta-analysis. We searched MEDLINE, Embase, ClinicalTrials.gov, Cumulative Index to Nursing and Allied Health Literature, and the Cochrane Library for studies reporting on the

  4. Biofuels and the Environment: The First Triennial Report to Congress (External Review Draft)

    Science.gov (United States)

    The Biofuels and the Environment: The First Triennial Report to Congress (External Review Draft) (EPA/600/R-10/183A) report, prepared by the National Center for Environmental Assessment (NCEA) within EPA’s Office of Research and Development, is the first report published ...

  5. [Review of traditional Chinese medicine external applications to treat chemistry phlebitis].

    Science.gov (United States)

    Sha, Sha; Liu, Weiqun; Cheng, Lushan; Ge, Jinjin

    2011-09-01

    This article reviewed the literatures in this area over the past 5 years according to three parts: simple traditional Chinese medicine external application, combination of traditional Chinese medicine and Western medicine, combination of traditional Chinese medicine and physical therapy, and came to several effective prescriptions.

  6. Acceptance and compliance with external hip protectors: A systematic review of the literature

    NARCIS (Netherlands)

    van Schoor, N.M.; Deville, W.L.J.M.; Bouter, L.M.; Lips, P.T.A.M.

    2002-01-01

    Hip fractures may be prevented by the use of external hip protectors, but compliance is often poor. Therefore, the objective of this study was to assess the determinants of compliance with hip protectors by systematically reviewing the literature. A literature search was performed in PubMed, Embase

  7. Acceptance and compliance with external hip protectors: a systematic review of the literature.

    NARCIS (Netherlands)

    Schoor, N.M. van; Devillé, W.L.; Bouter, L.M.; Lips, P.

    2002-01-01

    Hip fractures may be prevented by the use of external hip protectors, but compliance is often poor. Therefore, the objective of this study was to assess the determinants of compliance with hip protectors by systematically reviewing the literature. A literature search was performed in PubMed, Embase

  8. 45 CFR 147.136 - Internal claims and appeals and external review processes.

    Science.gov (United States)

    2010-10-01

    ..., appropriateness, health care setting, level of care, or effectiveness of a covered benefit. (ii) The State process... pay the cost of the IRO for conducting the external review. Notwithstanding this requirement, the... not impose, for example, a $500 minimum claims threshold. (vi) The State process must allow at least...

  9. External Quality Arrangements for the Review of Modern Apprenticeship Off-the-Job Training

    Science.gov (United States)

    Education Scotland, 2015

    2015-01-01

    This publication provides a quality framework to provide a structure for external review of Modern Apprenticeship off-the-job training.? The indicators in this framework are arranged under three key principles, addressing five questions which Education Scotland is adopting for evaluation purposes. These are underpinned by a wider principle on the…

  10. Automated process flowsheet synthesis for membrane processes using genetic algorithm: role of crossover operators

    KAUST Repository

    Shafiee, Alireza

    2016-06-25

    In optimization-based process flowsheet synthesis, optimization methods, including genetic algorithms (GA), are used as advantageous tools to select a high performance flowsheet by ‘screening’ large numbers of possible flowsheets. In this study, we expand the role of GA to include flowsheet generation through proposing a modified Greedysub tour crossover operator. Performance of the proposed crossover operator is compared with four other commonly used operators. The proposed GA optimizationbased process synthesis method is applied to generate the optimum process flowsheet for a multicomponent membrane-based CO2 capture process. Within defined constraints and using the random-point crossover, CO2 purity of 0.827 (equivalent to 0.986 on dry basis) is achieved which results in improvement (3.4%) over the simplest crossover operator applied. In addition, the least variability in the converged flowsheet and CO2 purity is observed for random-point crossover operator, which approximately implies closeness of the solution to the global optimum, and hence the consistency of the algorithm. The proposed crossover operator is found to improve the convergence speed of the algorithm by 77.6%.

  11. Processing flowsheet for the accelerator transmutation of waste (ATW) program

    International Nuclear Information System (INIS)

    Dewey, H.; Walker, R.; Yarbro, S.

    1992-01-01

    At Los Alamos, an innovative approach to transmuting long-lived radioactive waste is under investigation. The concept is to use a linear proton accelerator coupled to a solid target to produce an intense neutron flux. The intense stream of neutrons can then be used to fission or transmute long-lived radionuclides to either stable or shorter-lived isotopes. For the program to be successful, robust chemical separations with high efficiencies (>10 5 ) are required. The actual mission, either defense or commercial, will determine what suite of unit operations will be needed. If the mission is to process commercial spent fuel, there are several options available for feed preparation and blanket processing. The baseline option would be an improved PUREX system with the main alternative being the current ATW actinide blanket processing flowsheet. 99 Tc and 129 I are more likely to reach the biosphere than the actinides. Many models have been developed for predicting how the radionuclides will behave in a repository over long time periods. The general conclusion is that the actinides will be sorbed by the soil. Therefore, over a long time period, e.g., a million years their hazard will be lessened because of radioactive decay and dispersion. However, some of the long-lived fission products are not sorbed and could potentially reach the environment over a few thousand year period. Hence, they could present a significant safety hazard. Because of limited resources, most of the priority has been focused on the actinide and technetium blanket assemblies

  12. External Tank Liquid Hydrogen (LH2) Prepress Regression Analysis Independent Review Technical Consultation Report

    Science.gov (United States)

    Parsons, Vickie s.

    2009-01-01

    The request to conduct an independent review of regression models, developed for determining the expected Launch Commit Criteria (LCC) External Tank (ET)-04 cycle count for the Space Shuttle ET tanking process, was submitted to the NASA Engineering and Safety Center NESC on September 20, 2005. The NESC team performed an independent review of regression models documented in Prepress Regression Analysis, Tom Clark and Angela Krenn, 10/27/05. This consultation consisted of a peer review by statistical experts of the proposed regression models provided in the Prepress Regression Analysis. This document is the consultation's final report.

  13. A review of privacy and usability issues in mobile health systems: Role of external factors.

    Science.gov (United States)

    Katusiime, Jane; Pinkwart, Niels

    2017-10-01

    The increased penetration of mobile devices has created opportunities in the health sector and led to emerging of mobile health systems. As much as the mobile health systems have registered tremendous progress, they have been faced with privacy and usability issues. Due to the sensitivity of health information, there is an ethical need to equip mobile health systems with adequate privacy measures. However, these systems should also be useable by the intended users. Even though many researchers are working on solutions, the issues still persist. External factors such as cultural differences have also contributed to the issues, yet they have been under researched. In this article, we conduct a systematic literature review of 22 articles, categorize and present privacy and usability issues and possible solutions. We then discuss the relevance and implications of external factors to the findings on privacy and usability. We end with recommendations to address these external factors.

  14. A Review of Last Mile Logistics Innovations in an Externalities Cost Reduction Vision

    Directory of Open Access Journals (Sweden)

    Luigi Ranieri

    2018-03-01

    Full Text Available In this paper, a review of the recent scientific literature contributions on innovative strategies for last mile logistics, focusing on externalities cost reduction, is presented. Transport is causing problems in urban areas, in particular in freight transport: modern cities need solutions to reduce externalities costs such as congestion, pollution and others, which have increased in the last few years, especially due to the growth of goods delivery. Online sales and globalization lead to new trends in freight transport, and moreover, a larger quantity of goods is expected to be delivered in the next future. In this context, most of the delivered goods end up in the city centers. Last mile logistics is the least efficient stage of the supply chain and comprises up to 28% of the total delivery cost. Therefore, the improvement of last mile logistics and a significant externalities reduction are very important challenges for researchers. New technologies and transport means, innovative techniques and organizational strategies allow handling in a more effective way the last mile delivery in urban areas. Based on the Systematic Literature Review (SLR method, recent papers that significantly contributed, with original proposals, to the reduction of externalities in urban logistics are identified and analyzed in this work. Furthermore, a classification of the papers dealing with the externality reduction problem is presented. It is consistent with a general formulation proposed to evaluate external costs in urban area. The innovative contributions are classified into five main categories: innovative vehicles, proximity stations or points, collaborative and cooperative urban logistics, optimization of transport management and routing, innovations in public policies and infrastructures. The new paradigm of smart logistics is based on the combination of these concepts and on the proposed innovations.

  15. Evaluation of conceptual flowsheets for incorporating Light Water Reactor (LWR) fuel materials in an advanced nuclear fuel cycle

    International Nuclear Information System (INIS)

    Bell, J.T.; Burch, W.D.; Collins, E.D.; Forsberg, C.W.; Prince, B.E.; Bond, W.D.; Campbell, D.O.; Delene, J.G.; Mailen, J.C.

    1990-08-01

    A preliminary study by a group of experts at ORNL has generated and evaluated a number of aqueous and non-aqueous flowsheets for recovering transuranium actinides from LWR fuel for use as fuel in an LMR and, at the same time, for transmutation of the wastes to less hazardous materials. The need for proliferation resistance was a consideration in the flowsheets. The current state of development of the flowsheets was evaluated and recommendations for additional study were made. 3 refs., 6 figs

  16. Chemical flowsheet conditions for preparing urania spheres by internal gelation

    International Nuclear Information System (INIS)

    Haas, P.A.; Begovich, J.M.; Ryon, A.D.; Vavruska, J.S.

    1979-01-01

    Small, ceramic urania spheres can be prepared for use as nuclear fuel by internal chemical gelation of uranyl nitrate solution droplets. Decomposition of hexamethylenetetramine (HMTA) dissolved in the uranyl nitrate solution releases ammonia to precipitate hydrated UO 3 . Previously established flowsheet conditions have been improved and modified at ORNL and have been applied to prepare dense UO 2 spheres with average diameters of 1200, 300, and 30 μm. Acid-deficient uranyl nitrate (ADUN) solutions up to 3.4 M in uranium with NO 3 - /U mole ratios of 1.5 to 1.7 are prepared by dissolution of U 3 O 8 or UO 3 . Continuous mixing of metered, cooled ADUN containing urea and HMTA solutions provides a smooth, regulated flow of the temperature-sensitive feed solution. The gelation times for solution drops in organic liquids at 45 to 95 0 C depend on both the chemical reaction rates and the rates of heat transfer. The gel properties vary with temperature and other gelation variables. Gelation conditions were determined which allow easy washing, drying, firing, and sintering to produce dense UO 2 spheres of all three sizes. The 1200- and 300-μm UO 2 spheres were pepared by gelation in trichloroethylene at 50 to 65 0 C; 2-ethyl-l-hexanol was used as the gelation medium to prepare 30-μm UO 2 spheres. Washing and drying requirements were determined. The gel dried to 225 0 C contains about 95% UO 3 ; the remaining components are H 2 O, NH 3 - , which are volatilized during firing to UO 2

  17. Preliminary flowsheet: Ion exchange for separation of cesium from Hanford tank waste using resorcinol-formaldehyde resin

    International Nuclear Information System (INIS)

    Penwell, D.L.

    1994-01-01

    This preliminary flowsheet document describes an ion exchange process which uses resorcinol-formaldehyde (R-F) resin to remove cesium from Hanford tank waste. The flowsheet describes one possible equipment configuration, and contains mass balances based on that configuration with feeds of Neutralized Current Acid Waste, and Double Shell Slurry Feed. The flowsheet also discusses process alternatives, unresolved issues, and development needs associated with the ion exchange process. It is expected that this flowsheet will evolve as open issues are resolved and progress is made on development needs. This is part of the Tank Waste Remediation Program at Hanford. 26 refs, 6 figs, 25 tabs

  18. A critical scoping review of external uses of comfrey (Symphytum spp.).

    Science.gov (United States)

    Frost, R; MacPherson, H; O'Meara, S

    2013-12-01

    External preparations of the herb comfrey (most commonly Symphytum officinale L.) are widely available for over-the-counter, practitioner and healthcare professional usage. Traditional practice suggests comfrey can be used to treat musculoskeletal disorders, wounds and various other conditions; however a full and critical coverage of the evidence base has not yet been undertaken. A critical scoping review was undertaken. Six bibliographic databases, 10 grey literature databases and nine trials registers were searched plus reference lists of included studies and a descriptive overview of comfrey. Randomised or non-randomised clinical trials assessing the external use of comfrey for any indication were included and methodological and reporting quality were assessed. Observational studies were included only in the assessment of adverse events. Studies were grouped and summarised according to the type of indication treated. Of 1348 identified records, 64 full texts were screened for inclusion and 26 were included in the review - 13 RCTs, 5 non-randomised controlled trials and 8 observational studies evaluating treatments for ankle distortion, back pain, abrasion wounds, venous leg ulcers and osteoarthritis. The majority of included trials had an overall unclear risk of bias due to poor quality of reporting. Few adverse events were reported. Individual clinical trials showed evidence of benefit for ankle distortion, back pain, abrasion wounds and osteoarthritis. Topical application appears to be safe but further rigorous assessment is needed. Systematic reviews focussing on particular indications may clarify the treatment effect and safety of external comfrey preparations. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. FLOWSHEET FOR ALUMINUM REMOVAL FROM SLUDGE BATCH 6

    International Nuclear Information System (INIS)

    Pike, J.; Gillam, J.

    2008-01-01

    Samples of Tank 12 sludge slurry show a substantially larger fraction of aluminum than originally identified in sludge batch planning. The Liquid Waste Organization (LWO) plans to formulate Sludge Batch 6 (SB6) with about one half of the sludge slurry in Tank 12 and one half of the sludge slurry in Tank 4. LWO identified aluminum dissolution as a method to mitigate the effect of having about 50% more solids in High Level Waste (HLW) sludge than previously planned. Previous aluminum dissolution performed in a HLW tank in 1982 was performed at approximately 85 C for 5 days and dissolved nearly 80% of the aluminum in the sludge slurry. In 2008, LWO successfully dissolved 64% of the aluminum at approximately 60 C in 46 days with minimal tank modifications and using only slurry pumps as a heat source. This report establishes the technical basis and flowsheet for performing an aluminum removal process in Tank 51 for SB6 that incorporates the lessons learned from previous aluminum dissolution evolutions. For SB6, aluminum dissolution process temperature will be held at a minimum of 65 C for at least 24 days, but as long as practical or until as much as 80% of the aluminum is dissolved. As planned, an aluminum removal process can reduce the aluminum in SB6 from about 84,500 kg to as little as 17,900 kg with a corresponding reduction of total insoluble solids in the batch from 246,000 kg to 131,000 kg. The extent of the reduction may be limited by the time available to maintain Tank 51 at dissolution temperature. The range of dissolution in four weeks based on the known variability in dissolution kinetics can range from 44 to more than 80%. At 44% of the aluminum dissolved, the mass reduction is approximately 1/2 of the mass noted above, i.e., 33,300 kg of aluminum instead of 66,600 kg. Planning to reach 80% of the aluminum dissolved should allow a maximum of 81 days for dissolution and reduce the allowance if test data shows faster kinetics. 47,800 kg of the dissolved

  20. Procafd: Computer Aided Tool for Synthesis-Design & Analysis of Chemical Process Flowsheets

    DEFF Research Database (Denmark)

    Kumar Tula, Anjan; Eden, Mario R.; Gani, Rafiqul

    2015-01-01

    and emission to the surrounding and many more. In terms of approaches to solve the synthesis-design problem three major lines of attack have emerged: (a) the knowledge based approach [1] which relies on engineering knowledge & problem insights, (b) the optimization approach [2] which relies on the use...... of mathematical programming techniques, (c) hybrid approach which combine two or more approaches. D’Anterroches [3] proposed a group contribution based hybrid approach to solve the synthesis-design problem where, chemical process flowsheets could be synthesized in the same way as atoms or groups of atoms...... parameters for the operations of the high ranked flowsheets are established through reverse engineering approaches based on driving forces available for each operation. In the final stage, rigorous simulation is performed to validate the synthesis-design. Note that since the flowsheet is synthesized...

  1. Purex Process Improvements for Pu and NP Control in Total Actinide Recycle Flowsheets

    International Nuclear Information System (INIS)

    Birkett, J.E.; Carrott, M.J.; Crooks, G.; Fox, O.D.; Maher, C.J.; Taylor, R.J.; Woodhead, D.A.

    2006-01-01

    Significant improvements are required in the Purex process to optimise it for Advanced Fuel Cycles. Two key challenges we have identified are, firstly, developing more efficient methods for U/Pu separations especially at elevated Pu concentrations and, secondly, improving recovery, control and routing of Np in a modified Purex process. A series of Purex-like flowsheets for improved Pu separations based on hydroxamic acids and are reported. Purex-like flowsheets have been tested on a glovebox-housed 30-stage miniature centrifugal contactor train. A series of trials have been performed to demonstrate the processing of feeds with varying Pu contents ranging from 7 - 40% by weight. These flowsheets have demonstrated hydroxamic acids are excellent reagents for complexant stripping of Pu being able to achieve high decontamination factors (DF) on both the U and Pu product streams and co - recover Np with Pu. The advantages of a complexant-based approach are shown to be especially relevant when AFC scenarios are considered, where the Pu content of the fuel is expected to b e significantly higher. Recent results towards modifying the Purex process to improve recovery and control of Np in short residence time contactors are reported. Work on the development of chemical and process models to describe the complicated behaviour of Np under primary separation conditions (i.e. the HA extraction contactor) is described. To test the performance of the model a series of experiments were performed including testing of flowsheets on a fume-hood housed miniature centrifugal contactor train. The flowsheet was designed to emulate the conditions of a primar y separations contactor with the Np split between the U-solvent product and aqueous raffinate. In terms of Np routing the process model showed good agreement with flowsheet trial however much further work is required to fully understand this complex system. (authors)

  2. Formic Acid Free Flowsheet Development To Eliminate Catalytic Hydrogen Generation In The Defense Waste Processing

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, Dan P.; Stone, Michael E.; Newell, J. David; Fellinger, Terri L.; Bricker, Jonathan M.

    2012-09-14

    The Defense Waste Processing Facility (DWPF) processes legacy nuclear waste generated at the Savannah River Site (SRS) during production of plutonium and tritium demanded by the Cold War. The nuclear waste is first treated via a complex sequence of controlled chemical reactions and then vitrified into a borosilicate glass form and poured into stainless steel canisters. Converting the nuclear waste into borosilicate glass canisters is a safe, effective way to reduce the volume of the waste and stabilize the radionuclides. Testing was initiated to determine whether the elimination of formic acid from the DWPF's chemical processing flowsheet would eliminate catalytic hydrogen generation. Historically, hydrogen is generated in chemical processing of alkaline High Level Waste sludge in DWPF. In current processing, sludge is combined with nitric and formic acid to neutralize the waste, reduce mercury and manganese, destroy nitrite, and modify (thin) the slurry rheology. The noble metal catalyzed formic acid decomposition produces hydrogen and carbon dioxide. Elimination of formic acid by replacement with glycolic acid has the potential to eliminate the production of catalytic hydrogen. Flowsheet testing was performed to develop the nitric-glycolic acid flowsheet as an alternative to the nitric-formic flowsheet currently being processed at the DWPF. This new flowsheet has shown that mercury can be reduced and removed by steam stripping in DWPF with no catalytic hydrogen generation. All processing objectives were also met, including greatly reducing the Slurry Mix Evaporator (SME) product yield stress as compared to the baseline nitric/formic flowsheet. Ten DWPF tests were performed with nonradioactive simulants designed to cover a broad compositional range. No hydrogen was generated in testing without formic acid.

  3. External versus internal fixation for bicondylar tibial plateau fractures: systematic review and meta-analysis.

    Science.gov (United States)

    Metcalfe, David; Hickson, Craig J; McKee, Lesley; Griffin, Xavier L

    2015-12-01

    It is uncertain whether external fixation or open reduction internal fixation (ORIF) is optimal for patients with bicondylar tibial plateau fractures. A systematic review using Ovid MEDLINE, Embase Classic, Embase, AMED, the Cochrane Library, Open Grey, Orthopaedic Proceedings, WHO International Clinical Trials Registry Platform, Current Controlled Trials, US National Institute for Health Trials Registry, and the Cochrane Central Register of Controlled Trials. The search was conducted on 3rd October 2014 and no language limits were applied. Inclusion criteria were all clinical study designs comparing external fixation with open reduction internal fixation of bicondylar tibial plateau fractures. Studies of only one treatment modality were excluded, as were those that included unicondylar tibial plateau fractures. Treatment effects from studies reporting dichotomous outcomes were summarised using odds ratios. Continuous outcomes were converted to standardized mean differences to assess the treatment effect, and inverse variance methods used to combine data. A fixed effect model was used for meta-analyses. Patients undergoing external fixation were more likely to have returned to preinjury activities by six and twelve months (P = 0.030) but not at 24 months follow-up. However, external fixation was complicated by a greater number of infections (OR 2.59, 95 % CI 1.25-5.36, P = 0.01). There were no statistically significant differences in the rates of deep infection, venous thromboembolism, compartment syndrome, or need for re-operation between the two groups. Although external fixation and ORIF are associated with different complication profiles, both are acceptable strategies for managing bicondylar tibial plateau fractures.

  4. A review of United States yellow cake precipitation practice

    International Nuclear Information System (INIS)

    Litz, J.E.; Coleman, R.B.

    1980-01-01

    The various process flowsheets used to produce concentrated uranium solutions are reviewed. The choices of flowsheets are affected by ore alkalinity, uranium mineralization, and the impurities solubilized during leaching. The techniques used to precipitate yellow cake from concentrated uranium solutions are reviewed. Consideration is given to precipitation chemistry, reagent requirements, and process equipment and costs for precipitation, dewatering, drying and calcining. (author)

  5. Advanced Instrumentation, Information, and Control Systems Technologies Pathway: FY 2016 External Review

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Kenneth David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hallbert, Bruce Perry [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-11-01

    This report describes an External Review conducted by the LWRS Program Advanced Instrumentation, Information, and Control (II&C) Systems Technologies Pathway to solicit feedback on the topics and results of the ongoing II&C research program. This review was held in conjunction with the Nuclear Energy Institute (NEI) Digital I&C Working Group meeting that was held at Idaho National Laboratory (INL) on August 9-10, 2016. Given the opportunity to visit INL and see the pathway research projects, NEI agreed that the Working Group would serve as the External Review panel for the purpose of obtaining expert input on the value and timing of the research projects. This consisted of demonstrations in the Human Systems Simulation Laboratory followed by presentations on the II&C research program in general as well as the five technology development areas. Following the meeting, the presentations were sent to each of the attendees so they could review them in more detail and refer to them in completing the feedback form. Follow-up activities were conducted with the attendees following the meeting to obtain the completed feedback forms. A total of 13 forms were returned. The feedback forms were reviewed by the pathway to compile the data and comments received, which are documented in the report. In all, the feedback provided by the External Review participants is taken to be a strong endorsement of the types of projects being conducted by the pathway, the value they hold for the nuclear plants, and the general timing of need. The feedback aligns well with the priorities, levels of efforts allocated for the research projects, and project schedules. The feedback also represents realistic observations on the practicality of some aspects of implementing these technologies. In some cases, the participants provided thoughtful challenges to certain assumptions in the formulation of the technologies or in deployment plans. These deserve further review and revision of plans if warranted

  6. Advanced Instrumentation, Information, and Control Systems Technologies Pathway: FY 2016 External Review

    International Nuclear Information System (INIS)

    Thomas, Kenneth David; Hallbert, Bruce Perry

    2016-01-01

    This report describes an External Review conducted by the LWRS Program Advanced Instrumentation, Information, and Control (II&C) Systems Technologies Pathway to solicit feedback on the topics and results of the ongoing II&C research program. This review was held in conjunction with the Nuclear Energy Institute (NEI) Digital I&C Working Group meeting that was held at Idaho National Laboratory (INL) on August 9-10, 2016. Given the opportunity to visit INL and see the pathway research projects, NEI agreed that the Working Group would serve as the External Review panel for the purpose of obtaining expert input on the value and timing of the research projects. This consisted of demonstrations in the Human Systems Simulation Laboratory followed by presentations on the II&C research program in general as well as the five technology development areas. Following the meeting, the presentations were sent to each of the attendees so they could review them in more detail and refer to them in completing the feedback form. Follow-up activities were conducted with the attendees following the meeting to obtain the completed feedback forms. A total of 13 forms were returned. The feedback forms were reviewed by the pathway to compile the data and comments received, which are documented in the report. In all, the feedback provided by the External Review participants is taken to be a strong endorsement of the types of projects being conducted by the pathway, the value they hold for the nuclear plants, and the general timing of need. The feedback aligns well with the priorities, levels of efforts allocated for the research projects, and project schedules. The feedback also represents realistic observations on the practicality of some aspects of implementing these technologies. In some cases, the participants provided thoughtful challenges to certain assumptions in the formulation of the technologies or in deployment plans. These deserve further review and revision of plans if warranted

  7. Review of personal monitoring techniques for the measurement of absorbed dose from external beta and low energy photon radiation

    DEFF Research Database (Denmark)

    Christensen, Poul

    1986-01-01

    The techniques available at present for personal monitoring of doses from external beta and low energy photon radiation are reviewed. The performance of currently used dosimetry systems is compared with that recommended internationally, and developments for improving the actual performance...

  8. IRIS Toxicological Review of Ethylene Glycol Mono-Butyl Ether (Egbe) (External Review Draft)

    Science.gov (United States)

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of ethylene glycol monobutyl ether that will appear on the Integrated Risk Information System (IRIS) database.

  9. A Review of the New European Technical Recommendations for Monitoring Individuals Occupationally Exposed to External Radiation

    International Nuclear Information System (INIS)

    Dijk, J.W.E. van; Alves, J.G.; Ambrosi, P.; Bartlett, D.T.; Currivan, L.; Fantuzzi, E.; Kamenopoulou, V.

    2013-01-01

    This paper reviews the revised Technical Recommendations for Monitoring Individuals Occupationally Exposed to External Radiation as issued by the European Commission as Radiation Protection 160. These recommendations are aimed at all stakeholders in radiation protection dosimetry with an emphasis in the responsible technical staff of approved dosimetry services. This paper briefly touches each Chapter and ends with a more in depth section on the uncertainty evaluation of dose measurements. -- Highlights: ► Recommendations on all aspects of running an approved dosimetry service. ► Radiation protection framework. ► Metrology of personal dosimeters. ► QC and QA of individual monitoring

  10. External validation of multivariable prediction models: a systematic review of methodological conduct and reporting

    Science.gov (United States)

    2014-01-01

    Background Before considering whether to use a multivariable (diagnostic or prognostic) prediction model, it is essential that its performance be evaluated in data that were not used to develop the model (referred to as external validation). We critically appraised the methodological conduct and reporting of external validation studies of multivariable prediction models. Methods We conducted a systematic review of articles describing some form of external validation of one or more multivariable prediction models indexed in PubMed core clinical journals published in 2010. Study data were extracted in duplicate on design, sample size, handling of missing data, reference to the original study developing the prediction models and predictive performance measures. Results 11,826 articles were identified and 78 were included for full review, which described the evaluation of 120 prediction models. in participant data that were not used to develop the model. Thirty-three articles described both the development of a prediction model and an evaluation of its performance on a separate dataset, and 45 articles described only the evaluation of an existing published prediction model on another dataset. Fifty-seven percent of the prediction models were presented and evaluated as simplified scoring systems. Sixteen percent of articles failed to report the number of outcome events in the validation datasets. Fifty-four percent of studies made no explicit mention of missing data. Sixty-seven percent did not report evaluating model calibration whilst most studies evaluated model discrimination. It was often unclear whether the reported performance measures were for the full regression model or for the simplified models. Conclusions The vast majority of studies describing some form of external validation of a multivariable prediction model were poorly reported with key details frequently not presented. The validation studies were characterised by poor design, inappropriate handling

  11. External suction versus water seal after selective pulmonary resection for lung neoplasm: a systematic review.

    Directory of Open Access Journals (Sweden)

    Tong Qiu

    whether external suction should be routinely applied after lung neoplasm SPR. More high-quality randomized controlled trials are needed. SYSTEMATIC REVIEW REGISTRATION: None.

  12. Should Rehabilitation Specialists Use External Focus Instructions When Motor Learning Is Fostered? A Systematic Review

    Directory of Open Access Journals (Sweden)

    Tanja H. Kakebeeke

    2013-06-01

    Full Text Available According to the Constrained Action Hypothesis, motor learning is believed to be more efficient when an external focus (EF of motor control is given to the performer instead of an internal focus (IF of motor control. This systematic review investigated whether findings of studies focusing on the Constrained Action Hypothesis may be transferred to rehabilitation settings by assessing the methodological quality and risk of bias (ROB of available randomized controlled trials (RCTs. Of the 18 selected reports representing 20 RCTs, the methodological quality was rather low, and the majority of the reports appeared to have a high ROB. The 18 reports included 68 patients tested in a rehabilitation setting and 725 healthy participants. The time scale of the motor learning processes presented in the selected articles was heterogenic. The results of this systematic review indicate that the assumption that an external focus of control is to be preferred during motor learning processes is not sufficiently substantiated. The level of available evidence is not large enough to warrant transfer to patient populations (including children and the elderly and raises doubts about research with healthy individuals. This implies that based on the methodology used so far, there seems to be insufficient evidence for the superiority of an external focus of control, neither in healthy individuals nor in clinical populations. The relationship between EF instructions and motor learning research and its effect in both patient rehabilitation settings and healthy populations requires further exploration. Future adequately powered studies with low ROB and with rehabilitation populations that are followed over extended time periods should, therefore, be performed to substantiate or refute the assumption of the superiority of an EF in motor learning.

  13. IRIS Toxicological Review of Methanol (Non-Cancer) (External Review Draft; April 2011)

    Science.gov (United States)

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of methanol (non-cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  14. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (External Review Draft, 2009)

    Science.gov (United States)

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of ethyl tertiary butyl ether (ETBE) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  15. Preliminary flowsheet for the conversion of Hanford high-level waste to glass

    International Nuclear Information System (INIS)

    Beary, M.M.; Chick, L.A.; Ely, P.C.; Gott, S.A.

    1977-06-01

    The flowsheets describe a process for converting waste removed from the Hanford underground waste tanks to more immobile form. The process involves a chemical separation of the radionuclides from industrial chemicals, and then making glass from the resulting small volume of highly radioactive waste. Removal of Sr, actinides, cesium, and technetium is discussed

  16. Evaluation of quartz melt rate furnace with the nitric-glycolic flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    Williams, M. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Miller, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-08-03

    The Savannah River National Laboratory (SRNL) was tasked to support validation of the Defense Waste Processing Facility (DWPF) melter offgas flammability model for the Nitric-Glycolic (NG) flowsheet. The work is supplemental to the Cold Cap Evaluation Furnace (CEF) testing conducted in 20141 and the Slurry-fed Melt Rate Furnace (SMRF) testing conducted in 20162 that supported Deliverable 4 of the DWPF & Saltstone Facility Engineering Technical Task Request (TTR).3 The Quartz Melt Rate Furnace (QMRF) was evaluated as a bench-scale scoping tool to potentially be used in lieu of or simply prior to the use of the larger-scale SMRF or CEF. The QMRF platform has been used previously to evaluate melt rate behavior and offgas compositions of DWPF glasses prepared from the Nitric-Formic (NF) flowsheet but not for the NG flowsheet and not with continuous feeding.4 The overall objective of the 2016-2017 testing was to evaluate the efficacy of the QMRF as a lab-scale platform for steady state, continuously fed melter testing with the NG flowsheet as an alternative to more expensive and complex testing with the SMRF or CEF platforms.

  17. Prioritized List of Research Needs to support MRWFD Case Study Flowsheet Advancement

    International Nuclear Information System (INIS)

    Law, Jack Douglas; Soelberg, Nicholas Ray

    2015-01-01

    In FY-13, a case study evaluation was performed of full recycle technologies for both the processing of light-water reactor (LWR) used nuclear fuels as well as fast reactor (FR) fuel in the full recycle option. This effort focused on the identification of the case study processes and the initial preparation of material balance flowsheets for the identified technologies. In identifying the case study flowsheets, it was decided that two cases would be developed: one which identifies the flowsheet as currently developed and another near-term target flowsheet which identifies the flowsheet as envisioned within two years, pending the results of ongoing research. The case study focus is on homogeneous aqueous recycle of the U/TRU resulting from the processing of LWR fuel as feed for metal fuel fabrication. The metal fuel is utilized in a sodium-cooled fast reactor, and the used fast reactor fuel is processed using electrochemical separations. The recovered U/TRU from electrochemical separations is recycled to fuel fabrication and the fast reactor. Waste streams from the aqueous and electrochemical processing are treated and prepared for disposition. Off-gas from the separations and waste processing are also treated. As part of the FY-13 effort, preliminary process unknowns and research needs to advance the near-term target flowsheets were identified. In FY-14, these research needs were updated, expanded and prioritized. This report again updates the prioritized list of research needs based upon results to date in FY-15. The research needs are listed for each of the main portions of the flowsheet: 1) Aqueous headend, 2) Headend tritium pretreatment off-gas, 3) Aqueous U/Pu/Np recovery, 4) Aqueous TRU product solidification, 5) Aqueous actinide/lanthanide separation, 6) Aqueous off-gas treatment, 7) Aqueous HLW management, 8) Treatment of aqueous process wastes, 9) E-chem actinide separations, 10) E-chem off-gas, 11) E-chem HLW management. The identified research needs

  18. Prioritized List of Research Needs to support MRWFD Case Study Flowsheet Advancement

    Energy Technology Data Exchange (ETDEWEB)

    Law, Jack Douglas [Idaho National Lab. (INL), Idaho Falls, ID (United States); Soelberg, Nicholas Ray [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-06-17

    In FY-13, a case study evaluation was performed of full recycle technologies for both the processing of light-water reactor (LWR) used nuclear fuels as well as fast reactor (FR) fuel in the full recycle option. This effort focused on the identification of the case study processes and the initial preparation of material balance flowsheets for the identified technologies. In identifying the case study flowsheets, it was decided that two cases would be developed: one which identifies the flowsheet as currently developed and another near-term target flowsheet which identifies the flowsheet as envisioned within two years, pending the results of ongoing research. The case study focus is on homogeneous aqueous recycle of the U/TRU resulting from the processing of LWR fuel as feed for metal fuel fabrication. The metal fuel is utilized in a sodium-cooled fast reactor, and the used fast reactor fuel is processed using electrochemical separations. The recovered U/TRU from electrochemical separations is recycled to fuel fabrication and the fast reactor. Waste streams from the aqueous and electrochemical processing are treated and prepared for disposition. Off-gas from the separations and waste processing are also treated. As part of the FY-13 effort, preliminary process unknowns and research needs to advance the near-term target flowsheets were identified. In FY-14, these research needs were updated, expanded and prioritized. This report again updates the prioritized list of research needs based upon results to date in FY-15. The research needs are listed for each of the main portions of the flowsheet: 1) Aqueous headend, 2) Headend tritium pretreatment off-gas, 3) Aqueous U/Pu/Np recovery, 4) Aqueous TRU product solidification, 5) Aqueous actinide/lanthanide separation, 6) Aqueous off-gas treatment, 7) Aqueous HLW management, 8) Treatment of aqueous process wastes, 9) E-chem actinide separations, 10) E-chem off-gas, 11) E-chem HLW management. The identified research needs

  19. Tumor bed delineation for external beam accelerated partial breast irradiation: A systematic review

    International Nuclear Information System (INIS)

    Yang, T. Jonathan; Tao, Randa; Elkhuizen, Paula H.M.; Vliet-Vroegindeweij, Corine van; Li, Guang; Powell, Simon N.

    2013-01-01

    In recent years, accelerated partial breast irradiation (APBI) has been considered an alternative to whole breast irradiation for patients undergoing breast-conserving therapy. APBI delivers higher doses of radiation in fewer fractions to the post-lumpectomy tumor bed with a 1–2 cm margin, targeting the area at the highest risk of local recurrence while sparing normal breast tissue. However, there are inherent challenges in defining accurate target volumes for APBI. Studies have shown that significant interobserver variation exists among radiation oncologists defining the lumpectomy cavity, which raises the question of how to improve the accuracy and consistency in the delineation of tumor bed volumes. The combination of standardized guidelines and surgical clips significantly improves an observer’s ability in delineation, and it is the standard in multiple ongoing external-beam APBI trials. However, questions about the accuracy of the clips to mark the lumpectomy cavity remain, as clips only define a few points at the margin of the cavity. This paper reviews the techniques that have been developed so far to improve target delineation in APBI delivered by conformal external beam radiation therapy, including the use of standardized guidelines, surgical clips or fiducial markers, pre-operative computed tomography imaging, and additional imaging modalities, including magnetic resonance imaging, ultrasound imaging, and positron emission tomography/computed tomography. Alternatives to post-operative APBI, future directions, and clinical recommendations were also discussed

  20. Systematic review of adverse outcomes of external cephalic version and persisting breech presentation at term.

    Science.gov (United States)

    Nassar, Natasha; Roberts, Christine L; Barratt, Alexandra; Bell, Jane C; Olive, Emily C; Peat, Brian

    2006-03-01

    The aim of this study was to determine the frequency of adverse maternal and fetal outcomes of both external cephalic version (ECV) and persisting breech presentation at term. We conducted a systematic review of the literature using Medline, Embase and All Evidence Based Medicine (EBM) Reviews databases. Data were extracted from studies that compared women who had an ECV from 36 weeks' gestation with a similar control group of women enrolled at the same gestational age, eligible for, but who did not have an ECV. Eleven studies with a total of 2503 women were included. Adverse outcomes related to ECV were rarely reported and in most studies there was no evidence that relevant outcomes were ascertained among similar women who did not have an ECV. There was no increased risk of antepartum fetal death associated with ECV, but numbers were small. There were no reported cases of uterine rupture, placental abruption, prelabour rupture of membranes or cord prolapse, but these outcomes were not examined among controls. Onset of labour within 24 h and nuchal cord was non-significantly higher among women who had an ECV compared with those with a persisting breech. Despite limited reporting and small numbers, the results of our review suggest that adverse maternal and fetal outcomes of both ECV and persisting breech presentation are rare. Only with improved reporting and collection of safety data on ECV and persisting breech presentation can we provide high-quality information to assist informed decision making by pregnant women with a breech presentation at term.

  1. Human internal and external exposure to PBDEs--a review of levels and sources

    DEFF Research Database (Denmark)

    Frederiksen, Marie; Vorkamp, Katrin; Thomsen, Marianne

    2009-01-01

    This paper reviews the existing literature on human exposure to polybrominated diphenyl ethers (PBDEs), with particular focus on external exposure routes (e.g. dust, diet, and air) and the resulting internal exposure to PBDEs (e.g. breast milk and blood). Being lipophilic and persistent organic...... ingest more dust than adults. Infants are also exposed to PBDEs via breast milk. Internal human exposure has generally been found to be one order of magnitude larger in North America than in Europe and Asia. These differences cannot solely be explained by the dietary intake as meat products are the only...... food group where some differences has been observed. However, indoor air and dust concentrations have been found to be approximately one order of magnitude higher in North America than in Europe, possibly a result of different fire safety standards. Within Europe, higher PBDE concentrations in dust...

  2. A review of the hemodynamic effects of external leg and lower body compression.

    Science.gov (United States)

    Helmi, M; Gommers, D; Groeneveld, A B J

    2014-03-01

    External leg and lower body compression (ELC) has been used for decades in the prevention of deep vein thrombosis and the treatment of leg ischemia. Because of systemic effects, the methods have regained interest in anesthesia, surgery and critical care. This review intends to summarize hemodynamic effects and their mechanisms. Compilation of relevant literature published in English as full paper and retrieved from Medline. By compressing veins, venous stasis is diminished and venous return and arterial blood flow are increased. ELC has been suggested to improve systemic hemodynamics, in different clinical settings, such as postural hypotension, anesthesia, surgery, shock, cardiopulmonary resuscitation and mechanical ventilation. However, the hemodynamic alterations depend upon the magnitude, extent, cycle, duration and thus the modality of ELC, when applied in a static or intermittent fashion (by pneumatic inflation), respectively. ELC may help future research and optimizing treatment of hemodynamically unstable, surgical or critically ill patients, independent of plasma volume expansion.

  3. Review of SKB's Safety Assessment SR-Can: Contributions in Support of SKI's and SSI's Review by External Consultants

    International Nuclear Information System (INIS)

    2008-03-01

    The Swedish Nuclear Fuel and Waste Management Co (SKB) plans to submit a license application for the construction of a repository for spent nuclear fuel in Sweden 2010. In support of this application SKB will present a safety report, SR-Site, on the repository's long-term safety and radiological consequences. As a preparation for SR-Site, SKB published the preliminary safety assessment SR-Can in November 2006. The purposes were to document a first evaluation of long-term safety for the two candidate sites at Forsmark and Laxemar and to provide feedback to SKB's future programme of work. An important objective of the authorities' review of SR-Can is to provide guidance to SKB on the complete safety reporting for the license application. The authorities have engaged external experts for independent modelling, analysis and review, with the aim to provide a range of expert opinions related to the sufficiency and appropriateness of various aspects of SR-Can. The conclusions and judgments in this report are those of the authors and may not necessarily coincide with those of SKI and SSI. The authorities own review will be published separately (SKI Report 2008:23, SSI Report 2008:04 E). This report compiles contributions from several specific research projects. The separate reviews cover topics regarding the engineered barrier system, the quality assurance, the climate evolution and its effects, and the ecosystems and environmental impacts. All contributions are in English apart from the review concerning ecosystems and environmental impacts, which is presented in Swedish

  4. IPEEE Review of other external events of the NPP Asco; Revision del IPEEE de sucesos externos de C.N. Asco

    Energy Technology Data Exchange (ETDEWEB)

    Canadell, F.; Aleman, A.; Beltran, F.; Pifarre, D.; Hernandez, H.; Gasca, C.

    2011-07-01

    Within the process of maintaining and updating the risk analysis of the NPP Asco, results from the review of the vulnerability study of the plant against severe accidents caused by external success (Individual Plant Examination of External Events, IPEEE).

  5. External cephalic version in premature rupture of membranes: a systematic review.

    Science.gov (United States)

    Quist-Nelson, Johanna; Landers, Kathryn; McCurdy, Rebekah; Berghella, Vincenzo

    2017-09-01

    External cephalic version (ECV) increases the likelihood of a vaginal delivery in patients with breech presentation. Our objective was to determine the rate of cephalic vaginal delivery in women undergoing ECV after PROM. We performed a systematic review of all case reports, case series and clinical trials of patients undergoing an ECV after PROM ≥ 24 weeks. Maternal demographics and outcome data were obtained. The primary outcome was rate of cephalic vaginal delivery. Statistical analysis was performed for continuous outcomes by calculating mean and standard deviations for appropriate variables. The systematic review yielded six papers with 13 case reports and no clinical trials of ECV after PROM. The rate of success to cephalic presentation was 46.1% (six of 13 cases), with a subsequent vaginal delivery rate of 23.1% (three of 13 cases). The rate of umbilical cord prolapse was 33.3% (two of six cases). ECV after PROM has been reported in 13 cases in the literature. For the cases reported, 46.1% of ECV were successful in turning to cephalic position, but only 23.1% resulted in a vaginal delivery. There was a 33.3% incidence of umbilical cord prolapse. Given the high rate of umbilical cord prolapse, it would be imperative to offer an ECV in the setting of PROM only at an institution that has the ability to perform the indicated emergent cesarean delivery and only after appropriate counseling.

  6. Contraindications for external cephalic version in breech position at term: a systematic review.

    Science.gov (United States)

    Rosman, Ageeth N; Guijt, Aline; Vlemmix, Floortje; Rijnders, Marlies; Mol, Ben W J; Kok, Marjolein

    2013-02-01

    External cephalic version (ECV) is a safe and effective intervention that can prevent breech delivery, thus reducing the need for cesarean delivery. It is recommended in national guidelines. These guidelines also mention contraindications for ECV, and thereby restrict the application of ECV. We assessed whether the formulation of these contraindications in guidelines are based on empiric data. Systematic review. Pregnant women with a singleton breech presentation from 34 weeks. We searched the National Guideline Clearinghouse, the Cochrane Central Register of Controlled Trials, MEDLINE (1953-2009), EMBASE (1980-2009), TRIP database (until 2011), NHS (National Health Services, until 2011), Diseases database (until 2011) and NICE guidelines (until 2011) for existing guidelines on ECV and studied the reproducibility of the contraindications stated in the guidelines. Furthermore, we systematically reviewed the literature for contraindications and evidence on these contraindications. Contraindications of ECV. We found five guidelines mentioning 18 contraindications, varying from five to 13 per guideline. The contraindications were not reproducible between the guidelines with oligohydramnios as the only contraindication mentioned in all guidelines. The literature search yielded 60 studies reporting on 39 different contraindications, of which we could only assess evidence of six of them. The present study shows that there is no general consensus on the eligibility of patients for ECV. Therefore we propose to limit contraindications for ECV to clear empirical evidence or to those with a clear pathophysiological relevance. © 2012 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2012 Nordic Federation of Societies of Obstetrics and Gynecology.

  7. External Peer Review Team Report Underground Testing Area Subproject for Frenchman Flat, Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Sam Marutzky

    2010-09-01

    An external peer review was conducted to review the groundwater models used in the corrective action investigation stage of the Underground Test Area (UGTA) subproject to forecast zones of potential contamination in 1,000 years for the Frenchman Flat area. The goal of the external peer review was to provide technical evaluation of the studies and to assist in assessing the readiness of the UGTA subproject to progress to monitoring activities for further model evaluation. The external peer review team consisted of six independent technical experts with expertise in geology, hydrogeology,'''groundwater modeling, and radiochemistry. The peer review team was tasked with addressing the following questions: 1. Are the modeling approaches, assumptions, and model results for Frenchman Flat consistent with the use of modeling studies as a decision tool for resolution of environmental and regulatory requirements? 2. Do the modeling results adequately account for uncertainty in models of flow and transport in the Frenchman Flat hydrological setting? a. Are the models of sufficient scale/resolution to adequately predict contaminant transport in the Frenchman Flat setting? b. Have all key processes been included in the model? c. Are the methods used to forecast contaminant boundaries from the transport modeling studies reasonable and appropriate? d. Are the assessments of uncertainty technically sound and consistent with state-of-the-art approaches currently used in the hydrological sciences? 3. Are the datasets and modeling results adequate for a transition to Corrective Action Unit monitoring studies—the next stage in the UGTA strategy for Frenchman Flat? The peer review team is of the opinion that, with some limitations, the modeling approaches, assumptions, and model results are consistent with the use of modeling studies for resolution of environmental and regulatory requirements. The peer review team further finds that the modeling studies have accounted

  8. External Peer Review Team Report Underground Testing Area Subproject for Frenchman Flat, Revision 1

    International Nuclear Information System (INIS)

    Marutzky, Sam

    2010-01-01

    An external peer review was conducted to review the groundwater models used in the corrective action investigation stage of the Underground Test Area (UGTA) subproject to forecast zones of potential contamination in 1,000 years for the Frenchman Flat area. The goal of the external peer review was to provide technical evaluation of the studies and to assist in assessing the readiness of the UGTA subproject to progress to monitoring activities for further model evaluation. The external peer review team consisted of six independent technical experts with expertise in geology, hydrogeology,'groundwater modeling, and radiochemistry. The peer review team was tasked with addressing the following questions: 1. Are the modeling approaches, assumptions, and model results for Frenchman Flat consistent with the use of modeling studies as a decision tool for resolution of environmental and regulatory requirements? 2. Do the modeling results adequately account for uncertainty in models of flow and transport in the Frenchman Flat hydrological setting? a. Are the models of sufficient scale/resolution to adequately predict contaminant transport in the Frenchman Flat setting? b. Have all key processes been included in the model? c. Are the methods used to forecast contaminant boundaries from the transport modeling studies reasonable and appropriate? d. Are the assessments of uncertainty technically sound and consistent with state-of-the-art approaches currently used in the hydrological sciences? 3. Are the datasets and modeling results adequate for a transition to Corrective Action Unit monitoring studies the next stage in the UGTA strategy for Frenchman Flat? The peer review team is of the opinion that, with some limitations, the modeling approaches, assumptions, and model results are consistent with the use of modeling studies for resolution of environmental and regulatory requirements. The peer review team further finds that the modeling studies have accounted for uncertainty in

  9. An equation oriented approach to steady state flowsheeting of methanol synthesis loop

    International Nuclear Information System (INIS)

    Fathikalajahi, J.; Baniadam, M.; Rahimpour, M.R.

    2008-01-01

    An equation-oriented approach was developed for steady state flowsheeting of a commercial methanol plant. The loop consists of fixed bed reactor, flash separator, preheater, coolers, and compressor. For steady sate flowsheeting of the plant mathematical model of reactor and other units are needed. Reactor used in loop is a Lurgi type and its configuration is rather complex. Previously reactor and flash separator are modeled as two important units of plant. The model is based on mass and energy balances in each equipment and utilizing some auxiliary equations such as rate of reaction and thermodynamics model for activity coefficients of liquid. In order to validate the mathematical model for the synthesis loop, some simulation data were performed using operating conditions and characteristics of the commercial plant. The good agreement between the steady state simulation results and the plant data shows the validity of the model

  10. Effects of solvent-extraction contactor selection on flowsheet and facility design

    International Nuclear Information System (INIS)

    Whatley, M.E.

    1982-01-01

    The notion is developed that the selection of a solvent extraction contactor is part of a more general development of principles and philosophy guiding the overall plant design. Specifically, the requirements and constraints placed on the plant by the solvent extraction system must be consistent with those imposed by the other operations, which generally are more expensive and more complicated. Were a conservative philosophy employed throughout the plant, the choice of pulsed columns seem correct. Were the plant intended to employ modern techniques and state-of-the-art technology, particularly in remote maintenance and process control, the selection of centrifugal contactors seems appropriate. The process improvements attainable from employing more stages in a more tightly controlled solvent extraction system seem marginal at present when applied to conventional flowsheets, although the cost-benefit may be attractive in a modern plant. The potential for improvement through major flowsheet modification can not presently be assessed quantitatively

  11. Review and evaluation of performance measures for survival prediction models in external validation settings

    Directory of Open Access Journals (Sweden)

    M. Shafiqur Rahman

    2017-04-01

    Full Text Available Abstract Background When developing a prediction model for survival data it is essential to validate its performance in external validation settings using appropriate performance measures. Although a number of such measures have been proposed, there is only limited guidance regarding their use in the context of model validation. This paper reviewed and evaluated a wide range of performance measures to provide some guidelines for their use in practice. Methods An extensive simulation study based on two clinical datasets was conducted to investigate the performance of the measures in external validation settings. Measures were selected from categories that assess the overall performance, discrimination and calibration of a survival prediction model. Some of these have been modified to allow their use with validation data, and a case study is provided to describe how these measures can be estimated in practice. The measures were evaluated with respect to their robustness to censoring and ease of interpretation. All measures are implemented, or are straightforward to implement, in statistical software. Results Most of the performance measures were reasonably robust to moderate levels of censoring. One exception was Harrell’s concordance measure which tended to increase as censoring increased. Conclusions We recommend that Uno’s concordance measure is used to quantify concordance when there are moderate levels of censoring. Alternatively, Gönen and Heller’s measure could be considered, especially if censoring is very high, but we suggest that the prediction model is re-calibrated first. We also recommend that Royston’s D is routinely reported to assess discrimination since it has an appealing interpretation. The calibration slope is useful for both internal and external validation settings and recommended to report routinely. Our recommendation would be to use any of the predictive accuracy measures and provide the corresponding predictive

  12. An evaluation of five flowsheets for the recovery of uranium from Wits leach pulps

    International Nuclear Information System (INIS)

    Boydell, D.W.; Viljoen, E.B.

    1978-01-01

    This article evaluates five flowsheets for uranium recovery and an incremental net present value is calculated for each by the discounting of cash flows at 25 per cent per year over a projected life of 15 years. The highest net present value results from the circuit that employs belt filtration followed by continuous ion exchange, plus solvent extraction, in the particular case of the material used in the examples

  13. Interim glycol flowsheet reduction/oxidation (redox) model for the Defense Waste Processing Facility (DWPF)

    Energy Technology Data Exchange (ETDEWEB)

    Jantzen, C. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Williams, M. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Zamecnik, J. R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Missimer, D. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-03-08

    Control of the REDuction/OXidation (REDOX) state of glasses containing high concentrations of transition metals, such as High Level Waste (HLW) glasses, is critical in order to eliminate processing difficulties caused by overly reduced or overly oxidized melts. Operation of a HLW melter at Fe+2/ΣFe ratios of between 0.09 and 0.33, a range which is not overly oxidizing or overly reducing, helps retain radionuclides in the melt, i.e. long-lived radioactive 99Tc species in the less volatile reduced Tc4+ state, 104Ru in the melt as reduced Ru+4 state as insoluble RuO2, and hazardous volatile Cr6+ in the less soluble and less volatile Cr+3 state in the glass. The melter REDOX control balances the oxidants and reductants from the feed and from processing additives such as antifoam. Currently, the Defense Waste Processing Facility (DWPF) is running a formic acid-nitric acid (FN) flowsheet where formic acid is the main reductant and nitric acid is the main oxidant. During decomposition formate and formic acid releases H2 gas which requires close control of the melter vapor space flammability. A switch to a nitric acid-glycolic acid (GN) flowsheet is desired as the glycolic acid flowsheet releases considerably less H2 gas upon decomposition. This would greatly simplify DWPF processing. Development of an EE term for glycolic acid in the GN flowsheet is documented in this study.

  14. Actual waste demonstration of the nitric-glycolic flowsheet for sludge batch 9 qualification

    Energy Technology Data Exchange (ETDEWEB)

    Newell, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Pareizs, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Martino, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Reboul, S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Coleman, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Johnson, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-03-09

    For each sludge batch that is processed in the Defense Waste Processing Facility (DWPF), the Savannah River National Laboratory (SRNL) performs qualification testing to demonstrate that the sludge batch is processable. Based on the results of this actual-waste qualification and previous simulant studies, SRNL recommends implementation of the nitric-glycolic acid flowsheet in DWPF. Other recommendations resulting from this demonstration are reported in section 5.0.

  15. Development and Testing of an Americium/Lanthanide Separation Flowsheet Using Sodium Bismuthate

    Energy Technology Data Exchange (ETDEWEB)

    Jack Law; Bruce Mincher; Troy Garn; Mitchell Greenhalgh; Nicholas Schmitt; Veronica Rutledge

    2014-04-01

    The separation of Am from the lanthanides and curium is a key step in proposed advanced fuel cycle scenarios. The partitioning and transmutation of Am is desirable to minimize the long-term heat load of material interred in a future high-level waste repository. A separation process amenable to process scale-up remains elusive. Given only subtle chemistry differences within and between the ions of the trivalent actinide and lanthanide series this separation is challenging ; however, higher oxidation states of americium can be prepared using sodium bismuthate and separated via solvent extraction using diamylamylphosphonate (DAAP) extraction. Among the other trivalent metals only Ce is also oxidized and extracted. Due to the long-term instability of Am(VI) , the loaded organic phase is readily selectively stripped to partition the actinide to a new acidic aqueous phase. Batch extraction distribution ratio measurements were used to design a flowsheet to accomplish this separation. Additionally, crossflow filtration was investigated as a method to filter the bismuthate solids from the feed solution prior to extraction. Results of the filtration studies, flowsheet development work and flowsheet performance testing using a centrifugal contactor are detailed.

  16. Sludge batch 9 simulant runs using the nitric-glycolic acid flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, D. P. [Savannah River Site (SRS), Aiken, SC (United States); Williams, M. S. [Savannah River Site (SRS), Aiken, SC (United States); Brandenburg, C. H. [Savannah River Site (SRS), Aiken, SC (United States); Luther, M. C. [Savannah River Site (SRS), Aiken, SC (United States); Newell, J. D. [Savannah River Site (SRS), Aiken, SC (United States); Woodham, W. H. [Savannah River Site (SRS), Aiken, SC (United States)

    2016-11-01

    Testing was completed to develop a Sludge Batch 9 (SB9) nitric-glycolic acid chemical process flowsheet for the Defense Waste Processing Facility’s (DWPF) Chemical Process Cell (CPC). CPC simulations were completed using SB9 sludge simulant, Strip Effluent Feed Tank (SEFT) simulant and Precipitate Reactor Feed Tank (PRFT) simulant. Ten sludge-only Sludge Receipt and Adjustment Tank (SRAT) cycles and four SRAT/Slurry Mix Evaporator (SME) cycles, and one actual SB9 sludge (SRAT/SME cycle) were completed. As has been demonstrated in over 100 simulations, the replacement of formic acid with glycolic acid virtually eliminates the CPC’s largest flammability hazards, hydrogen and ammonia. Recommended processing conditions are summarized in section 3.5.1. Testing demonstrated that the interim chemistry and Reduction/Oxidation (REDOX) equations are sufficient to predict the composition of DWPF SRAT product and SME product. Additional reports will finalize the chemistry and REDOX equations. Additional testing developed an antifoam strategy to minimize the hexamethyldisiloxane (HMDSO) peak at boiling, while controlling foam based on testing with simulant and actual waste. Implementation of the nitric-glycolic acid flowsheet in DWPF is recommended. This flowsheet not only eliminates the hydrogen and ammonia hazards but will lead to shorter processing times, higher elemental mercury recovery, and more concentrated SRAT and SME products. The steady pH profile is expected to provide flexibility in processing the high volume of strip effluent expected once the Salt Waste Processing Facility starts up.

  17. Integration of SWPF into the DWPF Flowsheet: Gap Analysis and Test Matrix Development

    Energy Technology Data Exchange (ETDEWEB)

    Peeler, D. K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2014-12-10

    Based on Revision 19 of the High Level Waste (HLW) System Plan, it is anticipated that the Salt Waste Processing Facility (SWPF) will be integrated into the Defense Waste Processing Facility (DWPF) flowsheet in October 2018 (or with Sludge Batch 11 (SB11)). Given that, Savannah River Remediation (SRR) has requested a technical basis be developed that validates the current Product Composition Control System (PCCS) models for use during the processing of the SWPF-based coupled flowsheet or that leads to the refinements of or modifications to the models that are needed so that the models may be used during the processing of the SWPF-based coupled flowsheet. To support this objective, Savannah River National Laboratory (SRNL) has completed three key interim activities prior to validation of the current or development of refined PCCS models over the anticipated glass composition region for SWPF processing. These three key activities include: (1) defining the glass compositional region over which SWPF is anticipated to be processed, (2) comparing the current PCCS model validation ranges to the SWPF glass compositional region from which compositional gaps can be identified, and (3) developing a test matrix to cover the compositional gaps.

  18. HYBRID SULFUR CYCLE FLOWSHEETS FOR HYDROGEN PRODUCTION USING HIGH-TEMPERATURE GAS-COOLED REACTORS

    Energy Technology Data Exchange (ETDEWEB)

    Gorensek, M.

    2011-07-06

    Two hybrid sulfur (HyS) cycle process flowsheets intended for use with high-temperature gas-cooled reactors (HTGRs) are presented. The flowsheets were developed for the Next Generation Nuclear Plant (NGNP) program, and couple a proton exchange membrane (PEM) electrolyzer for the SO2-depolarized electrolysis step with a silicon carbide bayonet reactor for the high-temperature decomposition step. One presumes an HTGR reactor outlet temperature (ROT) of 950 C, the other 750 C. Performance was improved (over earlier flowsheets) by assuming that use of a more acid-tolerant PEM, like acid-doped poly[2,2'-(m-phenylene)-5,5'-bibenzimidazole] (PBI), instead of Nafion{reg_sign}, would allow higher anolyte acid concentrations. Lower ROT was accommodated by adding a direct contact exchange/quench column upstream from the bayonet reactor and dropping the decomposition pressure. Aspen Plus was used to develop material and energy balances. A net thermal efficiency of 44.0% to 47.6%, higher heating value basis is projected for the 950 C case, dropping to 39.9% for the 750 C case.

  19. Saskatchewan external cost review : report prepared by a Joint Oil and Gas Industry - Saskatchewan Energy and Mines Committee

    International Nuclear Information System (INIS)

    Anon.

    1996-11-01

    The external costs associated with the operating phase of oil and gas wells in Saskatchewan, were reviewed. The report identified external costs and compared their competitiveness with those of other producing jurisdictions. The profitability of the oil and gas industry in Saskatchewan was also assessed in an effort to provide industry and government with an informational package for use for discussion purposes. The study showed that (1) the oil and gas industry has been a major force for economic growth within Saskatchewan, (2) the province will continue to face stiff competition from other jurisdictions for new oil and gas investment dollars, (3) the system used for determining and administering external costs vary widely from one jurisdiction to another, and (4) a number of external costs are not sensitive to well production rates or commodity price movements. tabs., figs

  20. Is the internal connection more efficient than external connection in mechanical, biological, and esthetical point of views? A systematic review.

    Science.gov (United States)

    Goiato, Marcelo Coelho; Pellizzer, Eduardo Piza; da Silva, Emily Vivianne Freitas; Bonatto, Liliane da Rocha; dos Santos, Daniela Micheline

    2015-09-01

    This systematic review aimed to evaluate if the internal connection is more efficient than the external connection and its associated influencing factors. A specific question was formulated according to the Population, Intervention, Control, and Outcome (PICO): Is internal connection more efficient than external connection in mechanical, biological, and esthetical point of views? An electronic search of the MEDLINE and the Web of Knowledge databases was performed for relevant studies published in English up to November 2013 by two independent reviewers. The keywords used in the search included a combination of "dental implant" and "internal connection" or "Morse connection" or "external connection." Selected studies were randomized clinical trials, prospective or retrospective studies, and in vitro studies with a clear aim of investigating the internal and/or external implant connection use. From an initial screening yield of 674 articles, 64 potentially relevant articles were selected after an evaluation of their titles and abstracts. Full texts of these articles were obtained with 29 articles fulfilling the inclusion criteria. Morse taper connection has the best sealing ability. Concerning crestal bone loss, internal connections presented better results than external connections. The limitation of the present study was the absence of randomized clinical trials that investigated if the internal connection was more efficient than the external connection. The external and internal connections have different mechanical, biological, and esthetical characteristics. Besides all systems that show proper success rates and effectiveness, crestal bone level maintenance is more important around internal connections than external connections. The Morse taper connection seems to be more efficient concerning biological aspects, allowing lower bacterial leakage and bone loss in single implants, including aesthetic regions. Additionally, this connection type can be successfully

  1. External validity of randomized controlled trials in older adults, a systematic review.

    Directory of Open Access Journals (Sweden)

    Floor J van Deudekom

    Full Text Available To critically assess the external validity of randomized controlled trials (RCTs it is important to know what older adults have been enrolled in the trials. The aim of this systematic review is to study what proportion of trials specifically designed for older patients report on somatic status, physical and mental functioning, social environment and frailty in the patient characteristics.PubMed was searched for articles published in 2012 and only RCTs were included. Articles were further excluded if not conducted with humans or only secondary analyses were reported. A random sample of 10% was drawn. The current review analyzed this random sample and further selected trials when the reported mean age was ≥ 60 years. We extracted geriatric assessments from the population descriptives or the in- and exclusion criteria.In total 1396 trials were analyzed and 300 trials included. The median of the reported mean age was 66 (IQR 63-70 and the median percentage of men in the trials was 60 (IQR 45-72. In 34% of the RCTs specifically designed for older patients somatic status, physical and mental functioning, social environment or frailty were reported in the population descriptives or the in- and exclusion criteria. Physical and mental functioning was reported most frequently (22% and 14%. When selecting RCTs on a mean age of 70 or 80 years the report of geriatric assessments in the patient characteristics was 46% and 85% respectively but represent only 5% and 1% of the trials.Somatic status, physical and mental functioning, social environment and frailty are underreported even in RCTs specifically designed for older patients published in 2012. Therefore, it is unclear for clinicians to which older patients the results can be applied. We recommend systematic to transparently report these relevant characteristics of older participants included in RCTs.

  2. External Validity and Model Validity: A Conceptual Approach for Systematic Review Methodology

    Directory of Open Access Journals (Sweden)

    Raheleh Khorsan

    2014-01-01

    Full Text Available Background. Evidence rankings do not consider equally internal (IV, external (EV, and model validity (MV for clinical studies including complementary and alternative medicine/integrative health care (CAM/IHC research. This paper describe this model and offers an EV assessment tool (EVAT© for weighing studies according to EV and MV in addition to IV. Methods. An abbreviated systematic review methodology was employed to search, assemble, and evaluate the literature that has been published on EV/MV criteria. Standard databases were searched for keywords relating to EV, MV, and bias-scoring from inception to Jan 2013. Tools identified and concepts described were pooled to assemble a robust tool for evaluating these quality criteria. Results. This study assembled a streamlined, objective tool to incorporate for the evaluation of quality of EV/MV research that is more sensitive to CAM/IHC research. Conclusion. Improved reporting on EV can help produce and provide information that will help guide policy makers, public health researchers, and other scientists in their selection, development, and improvement in their research-tested intervention. Overall, clinical studies with high EV have the potential to provide the most useful information about “real-world” consequences of health interventions. It is hoped that this novel tool which considers IV, EV, and MV on equal footing will better guide clinical decision making.

  3. Review of the Elementary Particles Physics in the External Electromagnetic Fields Studies at KEK

    Science.gov (United States)

    Konstantinova, O. Tanaka

    2017-03-01

    High Energy Accelerator Research Organization (KEK [1]) is a world class accelerator-based research laboratory. The field of its scientific interests spreads widely from the study of fundamental properties of matter, particle physics, nuclear physics to materials science, life science, technical researches, and industrial applications. Research outcomes from the laboratory achieved making use of high-energy particle beams and synchrotron radiation. Two synchrotron facilities of KEK, the Photon Factory (PF) ring and the Photon Factory Advanced Ring (PF-AR) are the second biggest synchrotron light source in Japan. A very wide range of the radiated light, from visible light to X-ray, is provided for a variety of materials science, biology, and life science [2]. KEK strives to work closely with national and international research institutions, promoting collaborative research activities. Advanced research and facilities provision are key factors to be at the frontier of the accelerator science. In this review I am going to discuss KEK overall accelerator-based science, and to consider light sources research and development. The state of arts of the current projects with respect to the elementary particles physics in the external electromagnetic fields is also stressed here.

  4. Performance of External Quality Control Reviews by Military Department Audit Agencies

    National Research Council Canada - National Science Library

    Berry, Wayne

    2000-01-01

    The Government auditing standards issued by the Comptroller General of the United States require organizations conducting audits in accordance with Government auditing standards to undergo an external...

  5. Transcanal endoscopic resection for leiomyoma of the external auditory canal and a review of the literature.

    Science.gov (United States)

    Ikeda, Ryoukichi; Tateda, Masaru; Okoshi, Akira; Morita, Shinkichi; Suzuki, Hiroyoshi; Hashimoto, Sho

    2016-02-01

    Leiomyoma usually originates from the uterus and alimentary tract, but in extremely rare cases leiomyoma can appear in the external auditory canal. Here we present a 37-year-old man with right auricular fullness. Preoperative findings suggested benign tumor or cholesteatoma in the right external auditory canal. We performed total resection using an endoauricular approach with transcanal endoscopic ear surgery. Histopathological and immunohistochemistry examination confirmed the diagnosis of leiomyoma of external auditory canal. Leiomyoma arising from soft tissue, including that in the external auditory canal, is classified into two types: that from the arrectores pilorum muscles and that from the muscle coats of blood vessels. Only four cases of leiomyoma of external auditor canal have been published in the English literature. The other four cases demonstrated vascular leiomyomas. This is the first report of leiomyoma of the EAC arising from arrectores pilorum muscles. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  6. Arteriovenous malformation of the external ear: a clinical assessment with a scoping review of the literature

    Directory of Open Access Journals (Sweden)

    Shin Hye Kim

    Full Text Available Abstract Introduction: Auricular Arteriovenous Malformation of the external ear is a rarely encountered disease; in particular, arteriovenous malformation arising from the auricle, with spontaneous bleeding, has seldom been reported. Objective: In the current study, we report an unusual case of late-onset auricular arteriovenous malformation originating from the posterior auricular artery that was confirmed by computed tomographic angiography. The case was successfully managed by pre-surgical intravascular embolization followed by total lesion excision. Prompted by this case, we also present a scoping review of the literature. Methods: A case of a 60 year-old man with right auricular arteriovenous malformation treated in our tertiary care center, and 52 patients with auricular arteriovenous malformation described in 10 case reports and a retrospective review are presented. Auricular arteriovenous malformation can manifest as swelling of the ear, pulsatile tinnitus, pain, and/or bleeding. On physical examination, a pulsatile swelling and/or a tender mass is evident. When arteriovenous malformation is suspected, the lesions should be visualized using imaging modalities that optimally detect vascular lesions, and managed via embolization, mass excision, or auricular resection. Effectiveness of the various diagnostic methods used and the treatment outcomes were analyzed. Results: Various imaging modalities including Doppler sonography, computed tomographic angiography, magnetic resonance angiography, and/or transfemoral cerebral angiography were used to diagnose 38 cases reported in the literature. In another 15 cases, no imaging was performed; treatment was determined solely by physical examination and auscultation. Of the total of 53 cases, 12 were not treated (their symptoms were merely observed whereas 20 underwent therapeutic embolization. In total, 32 patients, including 1 patient who was not treated and 10 with persistent or aggravated

  7. Validation and Refinement of a Pain Information Model from EHR Flowsheet Data.

    Science.gov (United States)

    Westra, Bonnie L; Johnson, Steven G; Ali, Samira; Bavuso, Karen M; Cruz, Christopher A; Collins, Sarah; Furukawa, Meg; Hook, Mary L; LaFlamme, Anne; Lytle, Kay; Pruinelli, Lisiane; Rajchel, Tari; Settergren, Theresa Tess; Westman, Kathryn F; Whittenburg, Luann

    2018-01-01

    Secondary use of electronic health record (EHR) data can reduce costs of research and quality reporting. However, EHR data must be consistent within and across organizations. Flowsheet data provide a rich source of interprofessional data and represents a high volume of documentation; however, content is not standardized. Health care organizations design and implement customized content for different care areas creating duplicative data that is noncomparable. In a prior study, 10 information models (IMs) were derived from an EHR that included 2.4 million patients. There was a need to evaluate the generalizability of the models across organizations. The pain IM was selected for evaluation and refinement because pain is a commonly occurring problem associated with high costs for pain management. The purpose of our study was to validate and further refine a pain IM from EHR flowsheet data that standardizes pain concepts, definitions, and associated value sets for assessments, goals, interventions, and outcomes. A retrospective observational study was conducted using an iterative consensus-based approach to map, analyze, and evaluate data from 10 organizations. The aggregated metadata from the EHRs of 8 large health care organizations and the design build in 2 additional organizations represented flowsheet data from 6.6 million patients, 27 million encounters, and 683 million observations. The final pain IM has 30 concepts, 4 panels (classes), and 396 value set items. Results are built on Logical Observation Identifiers Names and Codes (LOINC) pain assessment terms and extend the need for additional terms to support interoperability. The resulting pain IM is a consensus model based on actual EHR documentation in the participating health systems. The IM captures the most important concepts related to pain. Schattauer GmbH Stuttgart.

  8. The conceptual flowsheet of effluent treatment during preparing spherical fuel elements of HTR

    Energy Technology Data Exchange (ETDEWEB)

    Ying, Quan, E-mail: quanying@tsinghua.edu.cn; Xiao-tong, Chen; Bing, Liu; Gen-na, Fu; Yang, Wang; You-lin, Shao; Zhen-ming, Lu; Ya-ping, Tang; Chun-he, Tang

    2014-05-01

    High temperature gas-cooled reactor (HTR) is one of the advanced nuclear reactors owing to its inherent safety and broad applications. For HTR, one of the key components is the ceramic fuel element. During the preparation of spherical fuel elements, the radioactive effluent treatment is necessary. Referring to the current treatment technologies and methods, the conceptual flowsheet of low-level radioactive effluent treatment during preparing spherical fuel elements was established. According to the above treatment process, the uranium concentration was decreased from 200 mg/l to the level of discharged standard.

  9. Characterization of Neptunium Oxide Generated Using the HB-Line Phase II Flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    Duffey, J

    2003-08-29

    Approximately 98 grams of neptunium(IV) oxide (NpO{sub 2}) were produced at the Savannah River Technology Center (SRTC) for use in gas generation tests to support the neptunium stabilization program at the Savannah River Site (SRS). The NpO{sub 2} was produced according to the anticipated HB-Line flowsheet consisting of anion exchange, oxalate precipitation, filtration, and calcination. Characterization of the NpO{sub 2} product to be used in gas generation tests included bulk and tap density measurements, X-ray diffraction, particle size distribution, specific surface area measurements, and moisture analysis.

  10. External pancreatic duct stent reduces pancreatic fistula: a meta-analysis and systematic review.

    Science.gov (United States)

    Patel, Krishen; Teta, Anthony; Sukharamwala, Prashant; Thoens, Jonathan; Szuchmacher, Mauricio; DeVito, Peter

    2014-01-01

    Postoperative pancreatic fistula formation (POPF) remains one of the most common and detrimental complications following pancreaticojejunostomy (PJ). The aim of this meta-analysis is to analyze the efficacy of external pancreatic duct stent placement in preventing POPF formation following PJ. The primary end-point was the incidence of POPF formation following pancreaticoduodenectomy (PD) in the presence and absence of external stent placement. Secondary outcomes examined were the incidence of perioperative mortality, delayed gastric emptying, postoperative wound infection, operative time, blood loss, and length of hospital stay. Four trials were included comprising 416 patients. External pancreatic duct stenting was found to reduce the incidence of both any grade POPF formation (OR 0.37, 95% CI = 0.23 to 0.58, p = 0.0001) and clinically significant (grade B or C) POPF formation (OR 0.50, 95% CI = 0.30 to 0.84, p = 0.0009) following PD. The use of an external stent was also found to significantly lessen length of hospital stay (SMD -0.39, 95% CI = -0.63 to -0.15, p = 0.001). This analysis has shown that external pancreatic duct stenting is indeed efficacious in the incidence of both any grade as well as clinically significant POPF formation following PD. Length of hospital stay was also found to be significantly less by external duct stenting. Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  11. Review of external ocular compression: clinical applications of the ocular pressure estimator

    Directory of Open Access Journals (Sweden)

    Korenfeld MS

    2016-02-01

    Full Text Available Michael S Korenfeld,1,2 David K Dueker3 1Comprehensive Eye Care, Ltd. Washington, MO, USA; 2Washington University Department of Ophthalmology and Visual Sciences, St Louis, MO, USA; 3Ophthalmology, Hamad Medical Corporation, Doha, Qatar Purpose: The authors have previously validated an Ocular Pressure Estimator (OPE that can estimate the intraocular pressure (IOP during external ocular compression (EOC. The authors now apply the OPE in clinical states where EOC is clinically important. The original work is described for two periods of risk: during sleep and during the digital ocular massage (DOM maneuver used by surgeons after trabeculectomy to keep the operation functional. Other periods of risk for external ocular compression are then reviewed.Methods: The first protocol estimated the IOP in the dependent eye during simulated sleep. Subjects had their IOPs initially measured in an upright-seated position, immediately upon assuming a right eye dependent side sleeping position (with nothing contacting the eye, and then 5 minutes later while still in this position. While maintaining this position, the fluid filled bladder of the OPE was then placed between the subject’s closed eye and a pillow during simulated sleep. The IOP was continuously estimated in this position for 5 minutes. The subjects then had the IOP measured in both eyes in an upright-seated position. The second protocol determined if a larger vertical cup-to-disc ratio was more common on the side that patients reported they preferred to sleep on. The hypothesis was that chronic asymmetric, compression induced, elevations of IOP during sleep would be associated with otherwise unexplained asymmetry of the vertical cup-to-disc ratio. The third protocol assessed the IOP during DOM. The OPE was used to characterize the IOP produced during the DOM maneuver of five glaucoma surgeons. After this, 90 mmHg was chosen as a target pressure for DOM. The surgeons were then verbally coached

  12. Comparison of external dacryocystorhinostomy and 5-fluorouracil augmented endonasal laser dacryocystorhinostomy. A Retrospective review

    Directory of Open Access Journals (Sweden)

    Watts Patrick

    2001-01-01

    Full Text Available Purpose: To compare the success rates of external dacryocystorhinostomy (EXT-DCR with 5-fluorouracil (5-FU augmented endonasal laser dacryocystorhinostomy (ENL-DCR and to record the complications associated with 5-FU augmented ENL-DCR Materials and Methods: This was a retrospective non-randomised study. Forty-one patients with primary acquired nasolacrimal duct obstruction underwent an EXT-DCR (19 patients or an ENL-DCR (22 patients over a 3-year period. A Holmium YAG laser (Ho:YAG was used in the latter group of patients. Silicone tubes intubated in all patients were removed at three months. 5-FU was applied intraoperatively at the site of the ostium in the ENL-DCR patients. The median follow-up was 12 months (range 3-24 months for the ENL-DCR group and 22 months (range 6-28 months for the EXT-DCR group. The patency of the lacrimal system and the severity of epiphora were assessed at a final-review. Results: The median age of the EXT-DCR group was 77 years (range 53-87 and that of the ENL-DCR group was 71 years (range 23 to 84. There were 12 female patients in the former group and 19 in the latter. The percentage of success in the EXT-DCR group was 94.7% (95% confidence interval (CI = 75.4-99.1 = , and 63.6% in the ENL-DCR group (95% CI= 43.0-80.3. The confidence interval for the difference of 31.1% was 5.6-52.2. There was a statistically significant difference between the two groups, p=0.024 (Fisher exact test. Conclusions: These data suggest that EXT-DCR provides better results than 5-FU augmented ENL-DCR. However, ENL-DCR is the procedure of choice in certain circumstances such as in elderly, frail or medically unfit patients. Our results of 5-FU augmented ENL-DCR compare favourably with other published series.

  13. Engineering safety review mission Krsko NPP external events PSA. Ljubljana, Slovenia 19-23 February 1996. Final report

    International Nuclear Information System (INIS)

    Budnitz, R.J.; Smith, P.

    1996-01-01

    Within the scope of the TC Project RER/9/035, a review mission visited Ljubljana, Slovenia, 19-23 February 1996. Two outside experts, Messrs. R.J. Budnitz (USA) and Paul Smith (USA), as well as a staff member, A. Guerpinar (ESS-NSNI) took part in the review. The purpose of the mission was to assist the Slovenian Nuclear Safety Administration to review the external events PSA prepared by Krsko NPP consultants Westinghouse Energy Systems Europe and EQE International. Another seismic safety review was performed concurrently in Ljubljana involving the investigations in relation to the tectonic stability and reassessment of the design basis ground motion characterization for the Krsko NPP site

  14. Flowsheet Validation For The Permanganate Digestion Of REILLEX(trademark) HPQ Anion Resin

    International Nuclear Information System (INIS)

    Kyser, E.

    2009-01-01

    The flowsheet for the digestion of Reillex(trademark) HPQ was validated both under the traditional alkaline conditions and under strongly acidic conditions. Due to difficulty in performing a pH adjustment in the large tank where this flowsheet must be performed, the recommended digestion conditions were changed from pH 8-10 to 8 M HNO 3 . Thus, no pH adjustment of the solution is required prior to performing the permanganate addition and digestion and the need to sample the digestion tank to confirm appropriate pH range for digestion may be avoided. Neutralization of the acidic digestion solution will be performed after completion of the resin digestion cycle. The amount of permanganate required for this type of resin (Reillex(trademark) HPQ) was increased from 1 kg/L resin to 4 kg/L resin to reduce the amount of residual resin solids to a minimal amount ( 2 ) solids (1.71 kg/L resin) and involves the generation of a significant liquid volume due to the low solubility of permanganate. However, since only two batches of resin (40 L each) are expected to be digested, the total waste generated is limited.

  15. Energy consumption analysis of integrated flowsheets for production of fuel ethanol from lignocellulosic biomass

    International Nuclear Information System (INIS)

    Cardona Alzate, C.A.; Sanchez Toro, O.J.

    2006-01-01

    Fuel ethanol is considered one of the most important renewable fuels due to the economic and environmental benefits of its use. Lignocellulosic biomass is the most promising feedstock for producing bioethanol due to its global availability and to the energy gain that can be obtained when non-fermentable materials from biomass are used for cogeneration of heat and power. In this work, several process configurations for fuel ethanol production from lignocellulosic biomass were studied through process simulation using Aspen Plus. Some flowsheets considering the possibilities of reaction-reaction integration were taken into account among the studied process routes. The flowsheet variants were analyzed from the energy point of view utilizing as comparison criterion the energy consumption needed to produce 1 L of anhydrous ethanol. Simultaneous saccharification and cofermentation process with water recycling showed the best results accounting an energy consumption of 41.96 MJ/L EtOH. If pervaporation is used as dehydration method instead of azeotropic distillation, further energy savings can be obtained. In addition, energy balance was estimated using the results from the simulation and literature data. A net energy value of 17.65-18.93 MJ/L EtOH was calculated indicating the energy efficiency of the lignocellulosic ethanol

  16. Actual Waste Demonstration of the Nitric-Glycolic Flowsheet for Sludge Batch 9 Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Newell, J. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Pareizs, J. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Martino, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Reboul, S. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Coleman, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Johnson, F. C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-09-01

    For each sludge batch that is processed in the Defense Waste Processing Facility (DWPF), the Savannah River National Laboratory (SRNL) performs qualification testing to demonstrate that the sludge batch is processable. Testing performed by the Savannah River National Laboratory has shown glycolic acid to be effective in replacing the function of formic acid in the DWPF chemical process. The nitric-glycolic flowsheet reduces mercury, significantly lowers the catalytic generation of hydrogen and ammonia which could allow purge reduction in the Sludge Receipt and Adjustment Tank (SRAT), stabilizes the pH and chemistry in the SRAT and the Slurry Mix Evaporator (SME), allows for effective rheology adjustment, and is favorable with respect to melter flammability. In order to implement the new flowsheet, SRAT and SME cycles, designated SC-18, were performed using a Sludge Batch (SB) 9 slurry blended from SB8 Tank 40H and Tank 51H samples. The SRAT cycle involved adding nitric and glycolic acids to the sludge, refluxing to steam strip mercury, and dewatering to a targeted solids concentration. Data collected during the SRAT cycle included offgas analyses, process temperatures, heat transfer, and pH measurements. The SME cycle demonstrated the addition of glass frit and the replication of six canister decontamination additions. The demonstration concluded with dewatering to a targeted solids concentration. Data collected during the SME cycle included offgas analyses, process temperatures, heat transfer, and pH measurements. Slurry and condensate samples were collected for subsequent analysis

  17. Nitric-glycolic flowsheet evaluation with the slurry-fed melt rate furnace

    Energy Technology Data Exchange (ETDEWEB)

    Williams, M. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Miller, D. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Fowley, M. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Zamecnik, J. R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-03-01

    The Savannah River National Laboratory (SRNL) was tasked to support validation of the Defense Waste Processing Facility (DWPF) melter offgas flammability model for the nitric-glycolic (NG) flowsheet. The work supports Deliverable 4 of the DWPF & Saltstone Facility Engineering Technical Task Request (TTR)1 and is supplemental to the Cold Cap Evaluation Furnace (CEF) testing conducted in 2014.2 The Slurry-fed Melt Rate Furnace (SMRF) was selected for the supplemental testing as it requires significantly less resources than the CEF and could provide a tool for more rapid analysis of melter feeds in the future. The SMRF platform has been used previously to evaluate melt rate behavior of DWPF glasses, but was modified to accommodate analysis of the offgas stream. Additionally, the Melt Rate Furnace (MRF) and Quartz Melt Rate Furnace (QMRF) were utilized for evaluations. MRF data was used exclusively for melt behavior observations and REDuction/OXidation (REDOX) prediction comparisons and will be briefly discussed in conjunction with its support of the SMRF testing. The QMRF was operated similarly to the SMRF for the same TTR task, but will be discussed in a separate future report. The overall objectives of the SMRF testing were to; 1) Evaluate the efficacy of the SMRF as a platform for steady state melter testing with continuous feeding and offgas analysis; and 2) Generate supplemental melter offgas flammability data to support the melter offgas flammability modelling effort for DWPF implementation of the NG flowsheet.

  18. Simplified nuclear fuel reprocessing flowsheet: a single-cycle Purex process

    International Nuclear Information System (INIS)

    Montuir, M.; Dinh, B.; Baron, P.

    2004-01-01

    A simplified flowsheet with only one purification cycle instead of three is proposed for reprocessing spent nuclear fuel using the Purex process. A single-cycle flowsheet minimizes the process equipment required, the number of control points before transfer between process units, and the solvent and effluent quantities. For the uranium stream, an alpha barrier is used to strip any residual contaminants (Np, Th, Pu) from the uranium-loaded solvent. This additional step eliminates the need for a second uranium cycle. For the plutonium stream, an additional βγ co-decontamination step and a higher plutonium concentration are required before the oxalate conversion step; a plutonium 'half-cycle' is added downstream. The unloaded solvent from this half-cycle is returned to the selective plutonium stripping step, allowing significant plutonium half-cycle losses. It should be possible to reduce the number of stages in the half-cycle extraction step by recycling the raffinate to the upstream separation process. (authors)

  19. Hydrogen generation in SRAT with nitric acid and late washing flowsheets

    International Nuclear Information System (INIS)

    Hsu, C.W.

    1992-01-01

    Melter feed preparation processes, incorporating a final wash of the precipitate slurry feed to Defense Waste Processing Facility (DWPF) and a partial substitution of the SRAT formic acid requirement with nitric acid, should not produce peak hydrogen generation rates during Cold Chemical Runs (CCR's) and radioactive operation greater than their current, respective hydrogen design bases of 0.024 lb/hr and 1.5 lb/hr. A single SRAT bench-scale process simulation for CCR-s produced a DWPF equivalent peak hydrogen generation rate of 0.004 lb/hr. During radioactive operation, the peak hydrogen generation rate will be dependent on the extent DWPF deviates from the nominal precipitate hydrolysis and melter feed preparation process operating parameters. Two actual radioactive sludges were treated according to the new flowsheets. The peak hydrogen evolution rates were equivalent to 0.038 and 0.20 lb/hr (DWPF scale) respectively. Compared to the formic acid -- HAN hydrolysis flowsheets, these peak rates were reduced by a factor of 2.5 and 3.4 for Tank 15 and Tank 11 sludges, respectively

  20. Energy consumption analysis of integrated flowsheets for production of fuel ethanol from lignocellulosic biomass

    Energy Technology Data Exchange (ETDEWEB)

    Cardona Alzate, C.A. [Department of Chemical Engineering, National University of Colombia at Manizales, Cra. 27 No. 64-60, Manizales (Colombia)]. E-mail: ccardonaal@unal.edu.co; Sanchez Toro, O.J. [Department of Chemical Engineering, National University of Colombia at Manizales, Cra. 27 No. 64-60, Manizales (Colombia); Department of Engineering, University of Caldas, Calle 65 No. 26-10, Manizales (Colombia)

    2006-10-15

    Fuel ethanol is considered one of the most important renewable fuels due to the economic and environmental benefits of its use. Lignocellulosic biomass is the most promising feedstock for producing bioethanol due to its global availability and to the energy gain that can be obtained when non-fermentable materials from biomass are used for cogeneration of heat and power. In this work, several process configurations for fuel ethanol production from lignocellulosic biomass were studied through process simulation using Aspen Plus. Some flowsheets considering the possibilities of reaction-reaction integration were taken into account among the studied process routes. The flowsheet variants were analyzed from the energy point of view utilizing as comparison criterion the energy consumption needed to produce 1 L of anhydrous ethanol. Simultaneous saccharification and cofermentation process with water recycling showed the best results accounting an energy consumption of 41.96 MJ/L EtOH. If pervaporation is used as dehydration method instead of azeotropic distillation, further energy savings can be obtained. In addition, energy balance was estimated using the results from the simulation and literature data. A net energy value of 17.65-18.93 MJ/L EtOH was calculated indicating the energy efficiency of the lignocellulosic ethanol.

  1. Contraindications for external cephalic version in breech position at term: a systematic review

    NARCIS (Netherlands)

    Rosman, Ageeth N.; Guijt, Aline; Vlemmix, Floortje; Rijnders, Marlies; Mol, Ben W. J.; Kok, Marjolein

    2013-01-01

    External cephalic version (ECV) is a safe and effective intervention that can prevent breech delivery, thus reducing the need for cesarean delivery. It is recommended in national guidelines. These guidelines also mention contraindications for ECV, and thereby restrict the application of ECV. We

  2. Contraindications for external cephalic version in breech position at term: A systematic review

    NARCIS (Netherlands)

    Rosman, A.N.; Guijt, A.; Vlemmix, F.; Rijnders, M.; Mol, B.W.J.; Kok, M.

    2013-01-01

    Objective. External cephalic version (ECV) is a safe and effective intervention that can prevent breech delivery, thus reducing the need for cesarean delivery. It is recommended in national guidelines. These guidelines also mention contraindications for ECV, and thereby restrict the application of

  3. [External progressive ophthalmoplegia secondary to mitochondrial myopathy. Report of a case and review of the literature].

    Science.gov (United States)

    Calderón-Garcidueñas, A L; Pérez-Loria, O; Alberto-Sagástegui, J; Farías-García, R

    2000-01-01

    Progressive limitation of occular motility, accompanied by ptosis but usually without diplopia, occurs in many pathologic states, including mitochondrial diseases. A case with chronic progressive external ophthalmoplegia with onset during childhood, associated with proximal myopathy and dysphasia is presented. The muscle biopsy showed a myopathic pattern and abnormal subsarcolemmal mitochondrial deposits. Muscle biopsy for important in the correct diagnosis of this entity.

  4. Emerging directions in lower limb externally wearable robots for gait rehabilitation and augmentation : A review

    NARCIS (Netherlands)

    Veneman, Jan F.; Burdet, Etienne; Van Der Kooij, Herman; Lefeber, Dirk; Tokhi, Mohammad O.; Virk, Gurvinder S.

    2016-01-01

    Wearable Robots, including those connected externally over the Lower Limbs (LLEWRs) is a growing field of research and development that promises robotic systems to support and augment locomotor functions. The current State of the Art of such products can be seen as a first generation of devices that

  5. Martial arts participation and externalizing behavior in juveniles : A meta-analytic review

    NARCIS (Netherlands)

    Gubbels, J.; van der Stouwe, T.; Spruit, A.; Stams, G.J.J.M.

    2016-01-01

    Martial arts are very popular among juveniles all over the world, but the relation between martial arts and externalizing behavior in juveniles remains unclear. The current multilevel meta-analysis of 12 studies, including 94 effect sizes and N = 5949 juveniles, was conducted to examine the relation

  6. Low-Cost Alternative External Rotation Shoulder Brace and Review of Treatment in Acute Shoulder Dislocations

    Directory of Open Access Journals (Sweden)

    Lacy, Kyle

    2015-01-01

    Full Text Available Traumatic dislocations of the shoulder commonly present to emergency departments (EDs. Immediate closed reduction of both anterior and posterior glenohumeral dislocations is recommended and is frequently performed in the ED. Recurrence of dislocation is common, as anteroinferior labral tears (Bankart lesions are present in many anterior shoulder dislocations.14,15,18,23 Immobilization of the shoulder following closed reduction is therefore recommended; previous studies support the use of immobilization with the shoulder in a position of external rotation, for both anterior and posterior shoulder dislocations.7-11,19 In this study, we present a technique for assembling a low-cost external rotation shoulder brace using materials found in most hospitals: cotton roll, stockinette, and shoulder immobilizers. This brace is particularly suited for the uninsured patient, who lacks the financial resources to pay for a pre-fabricated brace out of pocket. We also performed a cost analysis for our low-cost external rotation shoulder brace, and a cost comparison with pre-fabricated brand name braces. At our institution, the total materials cost for our brace was $19.15. The cost of a pre-fabricated shoulder brace at our institution is $150 with markup, which is reimbursed on average at $50.40 according to our hospital billing data. The low-cost external rotation shoulder brace is therefore a more affordable option for the uninsured patient presenting with acute shoulder dislocation. [West J Emerg Med. 2015;16(1:114–120.

  7. Radial nerve injury following elbow external fixator: report of three cases and literature review.

    Science.gov (United States)

    Trigo, Luis; Sarasquete, Juan; Noguera, Laura; Proubasta, Ignacio; Lamas, Claudia

    2017-07-01

    Radial nerve palsy is a rare but serious complication following elbow external fixation. Only 11 cases have been reported in the literature to date, but the incidence may be underreported. We present three new cases of this complication. We analyzed the three cases of radial palsy seen in our center following the application of an external fixator as treatment for complex elbow injuries. Mean patient age at surgery was 50 years. Two patients were female and one was male. In the three cases, the initial lesion was a posterior elbow dislocation, associated with a fracture of the radial shaft in one and a radial head fracture and coronoid fracture, respectively, in the other two. Due to persistent elbow instability, an external fixator was applied in all three cases. The fixator pins were introduced percutaneously in two cases and under direct vision in an open manner in the third case. Radial palsy was noted immediately postoperatively in all cases. It was permanent in two cases and temporary in the third. Radial nerve palsy after placement of an external elbow fixator was resolved in only 1 of our 3 cases and in 6 of the 11 cases in the literature to date. Although the event is rare, these alarming results highlight the need for recommendations to avoid this complication.

  8. Leaflet manual of external beam radiation therapy for hepatocellular carcinoma: a review of the indications, evidences, and clinical trials

    Directory of Open Access Journals (Sweden)

    Rim CH

    2018-05-01

    Full Text Available Chai Hong Rim, Won Sup Yoon Department of Radiation Oncology, Ansan Hospital, Korea University Medical College, Ansan, Republic of Korea Abstract: The use of external beam radiation therapy (EBRT in the treatment of hepatocellular carcinoma (HCC, which was rarely performed due to liver toxicity with a previous technique, has increased. Palliation of portal vein thrombosis, supplementation for insufficient transarterial chemoembolization, and provision of new curative opportunities using stereotactic body radiotherapy are the potential indications for use of EBRT. The mechanism of EBRT treatment, with its radiobiological and physical perspectives, differs from those of conventional medical treatment or surgery. Therefore, understanding the effects of EBRT may be unfamiliar to physicians other than radiation oncologists, especially in the field of HCC, where EBRT has recently begun to be applied. The first objective of this review was to concisely explain the indications for use of EBRT for HCC for all physicians treating HCC. Therefore, this review focuses on the therapeutic outcomes rather than the detailed biological and physical background. We also reviewed recent clinical trials that may extend the indications for use of EBRT. Finally, we reviewed the current clinical practice guidelines for the treatment of HCC and discuss the current recommendations and future perspectives. Keywords: hepatocellular carcinoma, liver neoplasm, external beam radiotherapy, stereotactic body radiotherapy, clinical trials, sorafenib, guidelines

  9. IPEEE review of external events of the Asco I nuclear plant; Revision del IPEEE de sucesos externos de la Central Nuclear Asco I

    Energy Technology Data Exchange (ETDEWEB)

    Aleman, A.; Canadell, F.; Beltran, F.; Pifarre, D.; Hernandez, H.; Gasca, C.

    2012-07-01

    During the risk analysis update of Asco PP (2010), it has been carried out a review of the vulnerabilities against severe accidents caused by external events (individual Plant Examination of external Events, IPEEE). The assessment has included analysis of accidents in industrial and military facilities nearby and transportation accidents (i.e., rail, road and aircraft impact) release of hazardous materials on site, external flooding, turbine missiles and strong winds. (Author)

  10. A retrospective review of how nonconformities are expressed and finalized in external inspections of health-care facilities.

    Science.gov (United States)

    Hovlid, Einar; Høifødt, Helge; Smedbråten, Bente; Braut, Geir Sverre

    2015-09-23

    External inspections are widely used in health care as a means of improving the quality of care. However, the way external inspections affect the involved organization is poorly understood. A better understanding of these processes is important to improve our understanding of the varying effects of external inspections in different organizations. In turn, this can contribute to the development of more effective ways of conducting inspections. The way the inspecting organization states their grounds for noncompliant behavior and subsequently follows up to enforce the necessary changes can have implications for the inspected organization's change process. We explore how inspecting organizations express and state their grounds for noncompliant behavior and how they follow up to enforce improvements. We conducted a retrospective review, in which we performed a content analysis of the documents from 36 external inspections in Norway. Our analysis was guided by Donabedian's structure, process, and outcome model. Deficiencies in the management system in combination with clinical work processes was considered as nonconformity by the inspecting organizations. Two characteristic patterns were identified in the way observations led to a statement of nonconformity: one in which it was clearly demonstrated how deficiencies in the management system could affect clinical processes, and one in which this connection was not demonstrated. Two characteristic patterns were also identified in the way the inspecting organization followed up and finalized their inspection: one in which the inspection was finalized solely based on the documented changes in structural deficiencies addressed in the nonconformity statement, and one based on the documented changes in structural and process deficiencies addressed in the nonconformity statement. External inspections are performed to improve the quality of care. To accomplish this aim, we suggest that nonconformities should be grounded by

  11. Comparison of external and internal implant-abutment connections for implant supported prostheses. A systematic review and meta-analysis.

    Science.gov (United States)

    Lemos, Cleidiel Aparecido Araujo; Verri, Fellippo Ramos; Bonfante, Estevam Augusto; Santiago Júnior, Joel Ferreira; Pellizzer, Eduardo Piza

    2018-03-01

    The systematic review and meta-analysis aimed to answer the PICO question: "Do patients that received external connection implants show similar marginal bone loss, implant survival and complication rates as internal connection implants?". Meta-analyses of marginal bone loss, survival rates of implants and complications rates were performed for the included studies. Study eligibility criteria included (1) randomized controlled trials (RCTs) and/or prospective, (2) studies with at least 10 patients, (3) direct comparison between connection types and (4) publications in English language. The Cochrane risk of bias tool was used to assess the quality and risk of bias in RCTs, while Newcastle-Ottawa scale was used for non-RCTs. A comprehensive search strategy was designed to identify published studies on PubMed/MEDLINE, Scopus, and The Cochrane Library databases up to October 2017. The search identified 661 references. Eleven studies (seven RCTs and four prospective studies) were included, with a total of 530 patients (mean age, 53.93 years), who had received a total of 1089 implants (461 external-connection and 628 internal-connection implants). The internal-connection implants exhibited lower marginal bone loss than external-connection implants (PInternal connections had lower marginal bone loss when compared to external connections. However, the implant-abutment connection had no influence on the implant's survival and complication rates. Based on the GRADE approach the evidence was classified as very low to moderate due to the study design, inconsistency, and publication bias. Thus, future research is highly encouraged. Internal connection implants should be preferred over external connection implants, especially when different risk factors that may contribute to increased marginal bone loss are present. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Externally Acquired Radiological Data for the Clinical Routine - A Review of the Reimbursement Situation in Germany.

    Science.gov (United States)

    Schreyer, Andreas G; Steinhäuser, René T; Rosenberg, Britta

    2018-02-07

     Interdisciplinary radiological conferences and boards can improve therapeutic pathways. Because of the reinterpretation and presentation of external image data, which already was read, an additional workload is created which is currently not considered by health care providers. In this review we discuss the ongoing basics and possibilities in health economy for a radiological second opinion for the outpatient and inpatient sector in Germany.  Based on up-to-date literature and jurisdiction, we discuss the most important questions for the reimbursement for second opinions and conference presentations of external image data in an FAQ format. Additionally, we focus on the recently introduced E-Health law accordingly.  Radiological services considering second opinion or board presentation of externally acquired image data are currently not adequately covered by health care providers. In particular, there is no reimbursement possibility for the inpatient sector. Only patients with private insurance or privately paid second opinions can be charged when these patients visit the radiologist directly.  Currently there is no adequate reimbursement possibility for a radiological second opinion or image demonstrations in clinical conferences. It will be essential to integrate adequate reimbursement by health care providers in the near future because of the importance of radiology as an essential diagnostic and therapeutic medical partner.   · Currently there is no reimbursement for image interpretation and presentation in boards.. · Second opinions can only be reimbursed for patients with private insurance or privately recompensed.. · The E-Health law allows reimbursement for tele-counsel in very complex situations.. · It will be crucial to integrate radiological second opinion in future reimbursement policies by health care providers.. · Schreyer AG, Steinhäuser RT, Rosenberg B. Externally Acquired Radiological Data for the Clinical Routine - A Review of

  13. Development of a SREX flowsheet for the separation of strontium from dissolved INEEL zirconium calcine

    International Nuclear Information System (INIS)

    Law, J.D.; Wood, D.J.; Todd, T.A.

    1999-01-01

    Laboratory experimentation has indicated that the SREX process is effective for partitioning 90 Sr from acidic radioactive waste solutions located at the Idaho Nuclear Technology and Engineering Center. These laboratory results were used to develop a flowsheet for countercurrent testing of the SREX process with dissolved pilot plant calcine. Testing was performed using 24 stages of 2-cm diameter centrifugal contactors which are installed in the Remote Analytical Laboratory hot cell. Dissolved Run No.64 pilot plant calcine spiked with 85 Sr was used as feed solution for the testing. The flowsheet tested consisted of an extraction section (0.15 M 4prime,4prime(5prime)-di-(tert-butylcyclohexo)-18-crown-6 and 1.5 M TBP in Isopar-L.), a 1.0 M NaNO 3 scrub section to remove extracted K from the SREX solvent, a 0.01 M HNO 3 strip section for the removal of Sr from the SREX solvent, a 0.25 M Na2CO 3 wash section to remove degradation products from the solvent, and a 0.1 M HNO 3 rinse section. The behavior of 85 Sr, Na, K, Al, B, Ca, Cr, Fe, Ni, and Zr was evaluated. The described flowsheet successfully extracted 85 Sr from the dissolved pilot plant calcine with a removal efficiency of 99.6%. Distribution coefficients for 85 Sr ranged from 3.6 to 4.5 in the extraction section. With these distribution coefficients a removal efficiency of approximately >99.99% was expected. It was determined that the lower than expected removal efficiency can be attributed to a stage efficiency of only 60% in the extraction section. Extracted K was effectively scrubbed from the SREX solvent with the 1.0 M NaNO 3 resulting in only 6.4% of the K in the HLW strip product. Sodium was not extracted from the dissolved calcine by the SREX solvent; however, the use of a 1.0 M NaNO 3 scrub solution resulted in a Na concentration of 70 mg/L (12.3% of the feed concentration) in the HLW strip product. Al, B, Ca, Cr, Fe, Ni, and Zr were determined to be essentially inextractable

  14. Development of an integrated MOX-scrap recycling flow-sheet by dry and wet routes using microwave heating techniques

    Energy Technology Data Exchange (ETDEWEB)

    Mallik, G K; Malav, R K; Karande, A P; Bhargava, V K; Kamath, H S [Advanced Fuel Fabrication Facility, Bhabha Atomic Research Centre, Tarapur (India)

    1999-01-01

    A simple, short and efficient scrap, recycling flow-sheet, which is exclusively based on microwave heating techniques and, includes both dry and wet routes, for (U,Pu)O{sub 2} fuel scrap recycling has been developed and evaluated. (author) 6 refs., 1 tab.

  15. Baseline Flowsheet Generation for the Treatment and Disposal of Idaho National Engineering and Environmental Laboratory Sodium Bearing Waste

    International Nuclear Information System (INIS)

    Barnes, C.M.; Lauerhass, L.; Olson, A.L.; Taylor, D.D.; Valentine, J.H.; Lockie, K.A.

    2002-01-01

    The High-Level Waste (HLW) Program at the Idaho National Engineering and Environmental Laboratory (INEEL) must implement technologies and processes to treat and qualify radioactive wastes located at the Idaho Nuclear Technology and Engineering Center (INTEC) for permanent disposal. This paper describes the approach and accomplishments to date for completing development of a baseline vitrification treatment flowsheet for sodium-bearing waste (SBW), including development of a relational database used to manage the associated process assumptions. A process baseline has been developed that includes process requirements, basis and assumptions, process flow diagrams, a process description, and a mass balance. In the absence of actual process or experimental results, mass and energy balance data for certain process steps are based on assumptions. Identification, documentation, validation, and overall management of the flowsheet assumptions are critical to ensuring an integrated, focused program. The INEEL HLW Program initially used a roadmapping methodology, developed through the INEEL Environmental Management Integration Program, to identify, document, and assess the uncertainty and risk associated with the SBW flowsheet process assumptions. However, the mass balance assumptions, process configuration and requirements should be accessible to all program participants. This need resulted in the creation of a relational database that provides formal documentation and tracking of the programmatic uncertainties related to the SBW flowsheet

  16. The use of external change agents to promote quality improvement and organizational change in healthcare organizations: a systematic review.

    Science.gov (United States)

    Alagoz, Esra; Chih, Ming-Yuan; Hitchcock, Mary; Brown, Randall; Quanbeck, Andrew

    2018-01-25

    External change agents can play an essential role in healthcare organizational change efforts. This systematic review examines the role that external change agents have played within the context of multifaceted interventions designed to promote organizational change in healthcare-specifically, in primary care settings. We searched PubMed, CINAHL, Cochrane, Web of Science, and Academic Search Premier Databases in July 2016 for randomized trials published (in English) between January 1, 2005 and June 30, 2016 in which external agents were part of multifaceted organizational change strategies. The review was conducted according to PRISMA guidelines. A total of 477 abstracts were identified and screened by 2 authors. Full text articles of 113 studies were reviewed. Twenty-one of these studies were selected for inclusion. Academic detailing (AD) is the most prevalently used organizational change strategy employed as part of multi-component implementation strategies. Out of 21 studies, nearly all studies integrate some form of audit and feedback into their interventions. Eleven studies that included practice facilitation into their intervention reported significant effects in one or more primary outcomes. Our results demonstrate that practice facilitation with regular, tailored follow up is a powerful component of a successful organizational change strategy. Academic detailing alone or combined with audit and feedback alone is ineffective without intensive follow up. Provision of educational materials and use of audit and feedback are often integral components of multifaceted implementation strategies. However, we didn't find examples where those relatively limited strategies were effective as standalone interventions. System-level support through technology (such as automated reminders or alerts) is potentially helpful, but must be carefully tailored to clinic needs.

  17. Review IPEEE C.N. external event Vandellos II; Revision del IPEEE de otros sucesos externos de C.N. Vandellos II

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez, H.; Gasca, C.; Beltran, F.; Salvat, M.; Pifarre, D.; Canadell, F.; Aleman, A.

    2010-07-01

    Within the process of maintaining and updating the risk analysis of CN Vandellos II, results from the review of the study of vulnerability of the plant against severe accidents caused by external events (Individual Plant Examination on Extornal Events, IPEEE).

  18. Development of some operations in technological flowsheet for spent VVER fuel reprocessing at a pilot plant

    International Nuclear Information System (INIS)

    Lazarev, L.N.; Galkin, B.Ya; Lyubtsev, R.I.; Romanovskii, V.N.; Velikhov, E.P.

    1981-01-01

    The fuel reprocessing pilot plants for high active materials would permit the study and development or particular processing steps and flowsheet variations; in some cases, these experimental installations realize on a small scale practically all technological chains of large reprocessing plants. Such a fuel reprocessing pilot plant with capacity of 3 kg U/d has been built at V. G. Khlopin Radium Institute. The pilot plant is installed in the hot cell of radiochemical compartment, and is composed of the equipments for fuel element cutting and dissolving, the preparation of feed solution (clarification, correction), extraction reprocessing and the production of uranium, plutonium and neptunium concentrates, the complex processing of liquid and solid wastes and a special unit for gas purification and analysis. In the last few years, a series of experiments have been carried out on the reprocessing of spent VVER fuel. (J.P.N.)

  19. DWPF nitric-glycolic flowsheet chemical process cell chemistry. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    Zamecnik, J. R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-02-01

    The conversions of nitrite to nitrate, the destruction of glycolate, and the conversion of glycolate to formate and oxalate were modeled for the Nitric-Glycolic flowsheet using data from Chemical Process Cell (CPC) simulant runs conducted by SRNL from 2011 to 2015. The goal of this work was to develop empirical correlations for these variables versus measureable variables from the chemical process so that these quantities could be predicted a-priori from the sludge composition and measurable processing variables. The need for these predictions arises from the need to predict the REDuction/OXidation (REDOX) state of the glass from the Defense Waste Processing Facility (DWPF) melter. This report summarizes the initial work on these correlations based on the aforementioned data. Further refinement of the models as additional data is collected is recommended.

  20. MO-A-BRB-01: Review of TG-262 Internal Survey of Practices in EMR for External Beam Therapy

    International Nuclear Information System (INIS)

    Mechalakos, J.

    2015-01-01

    The process of converting to an electronic chart for radiation therapy can be daunting. It requires a dedicated committee to first research and choose appropriate software, to review the entire documentation policy and flow of the clinic, to convert this system to electronic form or if necessary, redesign the system to more easily conform to the electronic process. Those making the conversion and those who already use electronic charting would benefit from the shared experience of those who have been through the process in the past. Therefore TG262 was convened to provide guidance on electronic charting for external beam radiation therapy and brachytherapy. This course will present the results of an internal survey of task group members on EMR practices in External Beam Radiation Therapy as well as discuss important issues in EMR development and structure for both EBRT and brachytherapy. Learning Objectives: Be familiarized with common practices and pitfalls in development and maintenance of an electronic chart in Radiation Oncology Be familiarized with important issues related to electronic charting in External Beam Radiation Therapy Be familiarized with important issues related to electronic charting in Brachytherapy

  1. Assessing Air Pollutant-Induced, Health-Related External Costs in the Context of Nonmarginal System Changes: A Review.

    Science.gov (United States)

    Bachmann, Till M

    2015-08-18

    Marginal analysis is the usual approach to environmental economic assessment, for instance, of health-related external costs due to energy-associated air pollutant emissions. However, nonlinearity exists in all steps of their assessment, i.e., atmospheric dispersion, impact assessment, and monetary valuation. Dedicated assessments thus appear necessary when evaluating large systems or their changes such as in green accounting or the implications of economy-wide energy transitions. Corresponding approaches are reviewed. Tools already exist that allow assessing a marginal change (e.g., one power plant's emissions) for different background emission scenarios that merely need to be defined and implemented. When assessing nonmarginal changes, the top-down approach is considered obsolete, and four variants of the bottom-up approach with different application domains were identified. Variants 1 and 2 use precalculated external cost factors with different levels of sophistication, suitable for energy systems modeling, optimizing for social (i.e., private and external) costs. Providing more reliable results due to more detailed modeling, emission sources are assessed individually or jointly in variants 3 and 4, respectively. Aiming at considering nonlinearity more fully and simultaneously following marginal analysis principles, I propose a variant 3-based approach, subdividing an aggregate (i.e., a nonmarginal change) into several smaller changes. Its strengths and drawbacks, notably the associated effort, are discussed.

  2. Hanford Low-Activity Waste Processing: Demonstration of the Off-Gas Recycle Flowsheet - 13443

    Energy Technology Data Exchange (ETDEWEB)

    Ramsey, William G.; Esparza, Brian P. [Washington River Protection Solutions, LLC, Richland, WA 99532 (United States)

    2013-07-01

    Vitrification of Hanford Low-Activity Waste (LAW) is nominally the thermal conversion and incorporation of sodium salts and radionuclides into borosilicate glass. One key radionuclide present in LAW is technetium-99. Technetium-99 is a low energy, long-lived beta emitting radionuclide present in the waste feed in concentrations on the order of 1-10 ppm. The long half-life combined with a high solubility in groundwater results in technetium-99 having considerable impact on performance modeling (as potential release to the environment) of both the waste glass and associated secondary waste products. The current Hanford Tank Waste Treatment and Immobilization Plant (WTP) process flowsheet calls for the recycle of vitrification process off-gas condensates to maximize the portion of technetium ultimately immobilized in the waste glass. This is required as technetium acts as a semi-volatile specie, i.e. considerable loss of the radionuclide to the process off-gas stream can occur during the vitrification process. To test the process flowsheet assumptions, a prototypic off-gas system with recycle capability was added to a laboratory melter (on the order of 1/200 scale) and testing performed. Key test goals included determination of the process mass balance for technetium, a non-radioactive surrogate (rhenium), and other soluble species (sulfate, halides, etc.) which are concentrated by recycling off-gas condensates. The studies performed are the initial demonstrations of process recycle for this type of liquid-fed melter system. This paper describes the process recycle system, the waste feeds processed, and experimental results. Comparisons between data gathered using process recycle and previous single pass melter testing as well as mathematical modeling simulations are also provided. (authors)

  3. Decontamination flowsheet development for a waste oil containing mixed radioactive contaminants

    International Nuclear Information System (INIS)

    Vijayan, S.; Buckley, L.P.

    1993-01-01

    The majority of waste oils contaminated with both radioactive and hazardous components are generated in nuclear power plant, research lab. and uranium-refinery operations. The waste oils are complex, requiring a detailed examination of the waste management strategies and technology options. It may appear that incineration offers a total solution, but this may not be true in all cases. An alternative approach is to decontaminate the waste oils to very low contaminant levels, so that the treated oils can be reused, burned as fuel in boilers, or disposed of by commercial incineration. This paper presents selected experimental data and evaluation results gathered during the development of a decontamination flowsheet for a specific waste oil stores at Chalk River Labs. (CRL). The waste oil contains varying amounts of lube oils, grease, paint, water, particulates, sludge, light chloro- and fluoro-solvents, polychlorinated biphenyls (PCB), complexing chemicals, uranium, chromium, iron, arsenic and manganese. To achieve safe management of this radioactive and hazardous waste, several treatment and disposal methods were screened. Key experiments were performed at the laboratory-scale to confirm and select the most appropriate waste-management scheme based on technical, environmental and economic criteria. The waste-oil-decontamination flowsheet uses a combination of unit operations, including prefiltration, acid scrubbing, and aqueous-leachage treatment by precipitation, microfiltration, filter pressing and carbon adsorption. The decontaminated oil containing open-quotes de minimisclose quotes levels of contaminants will undergo chemical destruction of PCBs and final disposal by incineration. The recovered uranium will be recycled to a uranium milling process

  4. FY13 GLYCOLIC-NITRIC ACID FLOWSHEET DEMONSTRATIONS OF THE DWPF CHEMICAL PROCESS CELL WITH SIMULANTS

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, D.; Zamecnik, J.; Best, D.

    2014-03-13

    Savannah River Remediation is evaluating changes to its current Defense Waste Processing Facility flowsheet to replace formic acid with glycolic acid in order to improve processing cycle times and decrease by approximately 100x the production of hydrogen, a potentially flammable gas. Higher throughput is needed in the Chemical Processing Cell since the installation of the bubblers into the melter has increased melt rate. Due to the significant maintenance required for the safety significant gas chromatographs and the potential for production of flammable quantities of hydrogen, eliminating the use of formic acid is highly desirable. Previous testing at the Savannah River National Laboratory has shown that replacing formic acid with glycolic acid allows the reduction and removal of mercury without significant catalytic hydrogen generation. Five back-to-back Sludge Receipt and Adjustment Tank (SRAT) cycles and four back-to-back Slurry Mix Evaporator (SME) cycles were successful in demonstrating the viability of the nitric/glycolic acid flowsheet. The testing was completed in FY13 to determine the impact of process heels (approximately 25% of the material is left behind after transfers). In addition, back-to-back experiments might identify longer-term processing problems. The testing was designed to be prototypic by including sludge simulant, Actinide Removal Product simulant, nitric acid, glycolic acid, and Strip Effluent simulant containing Next Generation Solvent in the SRAT processing and SRAT product simulant, decontamination frit slurry, and process frit slurry in the SME processing. A heel was produced in the first cycle and each subsequent cycle utilized the remaining heel from the previous cycle. Lower SRAT purges were utilized due to the low hydrogen generation. Design basis addition rates and boilup rates were used so the processing time was shorter than current processing rates.

  5. The Internal, External, and Diagnostic Validity of Sluggish Cognitive Tempo: A Meta-Analysis and Critical Review

    Science.gov (United States)

    Becker, Stephen P.; Leopold, Daniel R.; Burns, G. Leonard; Jarrett, Matthew A.; Langberg, Joshua M.; Marshall, Stephen A.; McBurnett, Keith; Waschbusch, Daniel A.; Willcutt, Erik G.

    2015-01-01

    Objective To conduct the first meta-analysis evaluating the internal and external validity of the sluggish cognitive tempo (SCT) construct as related to or distinct from attention-deficit/hyperactivity disorder (ADHD) and as associated with functional impairment and neuropsychological functioning. Method Electronic databases were searched through September 2015 for studies examining the factor structure and/or correlates of SCT in children or adults. The search procedures identified 73 papers. The core SCT behaviors included across studies, as well as factor loadings and reliability estimates, were reviewed to evaluate internal validity. Pooled correlation effect sizes using random effects models were used to evaluate SCT in relation to external validity domains (i.e., demographics, other psychopathologies, functional impairment, and neuropsychological functioning). Results Strong support was found for the internal validity of the SCT construct. Specifically, across factor analytic studies including over 19,000 individuals, 13 SCT items loaded consistently on an SCT factor as opposed to an ADHD factor. Findings also support the reliability (i.e., internal consistency, test-retest reliability, inter-rater reliability) of SCT. In terms of external validity, there is some indication that SCT may increase with age (r = 0.11) and be associated with lower socioeconomic status (r = 0.10). Modest (potentially negligible) support was found for SCT symptoms being higher in males than females in children (r = 0.05) but not adults. SCT is more strongly associated with ADHD inattention (r = 0.63 in children, r = 0.72 in adults) than with ADHD hyperactivity-impulsivity (r = 0.32 in children, r = 0.46 in adults), and it likewise appears that SCT is more strongly associated with internalizing symptoms than with externalizing symptoms. SCT is associated with significant global, social, and academic impairment (rs = 0.38–0.44). Effects for neuropsychological functioning are mixed

  6. The effect of video review of resident laparoscopic surgical skills measured by self- and external assessment.

    Science.gov (United States)

    Herrera-Almario, Gabriel E; Kirk, Katherine; Guerrero, Veronica T; Jeong, Kwonho; Kim, Sara; Hamad, Giselle G

    2016-02-01

    Video review of surgical skills is an educational modality that allows trainees to reflect on self-performance. The purpose of this study was to determine whether resident and attending assessments of a resident's laparoscopic performance differ and whether video review changes assessments. Third-year surgery residents were invited to participate. Elective laparoscopic procedures were video recorded. The Global Operative Assessment of Laparoscopic Skills evaluation was completed immediately after the procedure and again 7 to 10 days later by both resident and attending. Scores were compared using t tests. Nine residents participated and 76 video reviews were completed. Residents scored themselves significantly lower than the faculty scores both before and after video review. Resident scores did not change significantly after video review. Attending and resident self-assessment of laparoscopic skills differs and subsequent video review does not significantly affect Global Operative Assessment of Laparoscopic Skills scores. Further studies should evaluate the impact of video review combined with verbal feedback on skill acquisition and assessment. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Duplication of the External Auditory Canal: Two Cases and a Review of the Literature

    Science.gov (United States)

    Goudakos, John K.; Blioskas, Sarantis; Psillas, George; Vital, Victor; Markou, Konstantinos

    2012-01-01

    The objective of the present paper is to describe the clinical presentation, diagnostic process, surgical treatment, and outcome of 2 patients with first branchial cleft anomaly. The first case was an 8-year-old girl presented with an elastic lesion located in the left infra-auricular area, in close relation with the lobule, duplicating the external auditory canal. The magnetic resonance imaging revealed a lesion, appearing as a rather well-circumscribed mass within the left parotid gland and duplicating the ear canal. A superficial parotidectomy was subsequently performed, with total excision of the cyst. The second patient was a 15-year-old girl presented with a congenital fistula of the right lateral neck. At superficial parotidectomy, a total excision of the fistula was performed. During the operation the tract was recorded to lay between the branches of the facial nerve, extending with a blind ending canal parallel to the external acoustic meatus. Conclusively, first branchial cleft anomalies are rare malformations with cervical, parotid, or auricular clinical manifestations. Diagnosis of first branchial cleft lesions is achieved mainly through careful physical examination. Complete surgical excision with wide exposure of the lesion is essential in order to achieve permanent cure and avoid recurrence. PMID:23213587

  8. Duplication of the External Auditory Canal: Two Cases and a Review of the Literature

    Directory of Open Access Journals (Sweden)

    John K. Goudakos

    2012-01-01

    Full Text Available The objective of the present paper is to describe the clinical presentation, diagnostic process, surgical treatment, and outcome of 2 patients with first branchial cleft anomaly. The first case was an 8-year-old girl presented with an elastic lesion located in the left infra-auricular area, in close relation with the lobule, duplicating the external auditory canal. The magnetic resonance imaging revealed a lesion, appearing as a rather well-circumscribed mass within the left parotid gland and duplicating the ear canal. A superficial parotidectomy was subsequently performed, with total excision of the cyst. The second patient was a 15-year-old girl presented with a congenital fistula of the right lateral neck. At superficial parotidectomy, a total excision of the fistula was performed. During the operation the tract was recorded to lay between the branches of the facial nerve, extending with a blind ending canal parallel to the external acoustic meatus. Conclusively, first branchial cleft anomalies are rare malformations with cervical, parotid, or auricular clinical manifestations. Diagnosis of first branchial cleft lesions is achieved mainly through careful physical examination. Complete surgical excision with wide exposure of the lesion is essential in order to achieve permanent cure and avoid recurrence.

  9. External Costs of Risky Health Behaviors Associated with Leading Actual Causes of Death in the U.S.: A Review of the Evidence and Implications for Future Research

    Directory of Open Access Journals (Sweden)

    Armineh Zohrabian

    2010-06-01

    Full Text Available This paper reviews the evidence on external costs of risky behaviors in the U.S. and provides a framework for estimating them. External costs arise when a person does not bear all the costs of his or her behavior. They provide one of the strongest rationales for government interventions. Although the earlier estimates of external costs no longer have policy relevance, they demonstrated that the existence of external costs was an empirical question. We recommend that the estimates of external costs be updated as insurance structures, environments, and knowledge about these behaviors change. The general aspects of external costs may apply to countries other than the U.S. after taking into account differences in institutional, policy and epidemiological characteristics.

  10. External validation of a measurement tool to assess systematic reviews (AMSTAR.

    Directory of Open Access Journals (Sweden)

    Beverley J Shea

    Full Text Available BACKGROUND: Thousands of systematic reviews have been conducted in all areas of health care. However, the methodological quality of these reviews is variable and should routinely be appraised. AMSTAR is a measurement tool to assess systematic reviews. METHODOLOGY: AMSTAR was used to appraise 42 reviews focusing on therapies to treat gastro-esophageal reflux disease, peptic ulcer disease, and other acid-related diseases. Two assessors applied the AMSTAR to each review. Two other assessors, plus a clinician and/or methodologist applied a global assessment to each review independently. CONCLUSIONS: The sample of 42 reviews covered a wide range of methodological quality. The overall scores on AMSTAR ranged from 0 to 10 (out of a maximum of 11 with a mean of 4.6 (95% CI: 3.7 to 5.6 and median 4.0 (range 2.0 to 6.0. The inter-observer agreement of the individual items ranged from moderate to almost perfect agreement. Nine items scored a kappa of >0.75 (95% CI: 0.55 to 0.96. The reliability of the total AMSTAR score was excellent: kappa 0.84 (95% CI: 0.67 to 1.00 and Pearson's R 0.96 (95% CI: 0.92 to 0.98. The overall scores for the global assessment ranged from 2 to 7 (out of a maximum score of 7 with a mean of 4.43 (95% CI: 3.6 to 5.3 and median 4.0 (range 2.25 to 5.75. The agreement was lower with a kappa of 0.63 (95% CI: 0.40 to 0.88. Construct validity was shown by AMSTAR convergence with the results of the global assessment: Pearson's R 0.72 (95% CI: 0.53 to 0.84. For the AMSTAR total score, the limits of agreement were -0.19+/-1.38. This translates to a minimum detectable difference between reviews of 0.64 'AMSTAR points'. Further validation of AMSTAR is needed to assess its validity, reliability and perceived utility by appraisers and end users of reviews across a broader range of systematic reviews.

  11. Evaluation of marginal bone loss of dental implants with internal or external connections and its association with other variables: A systematic review.

    Science.gov (United States)

    de Medeiros, Rodrigo Antonio; Pellizzer, Eduardo Piza; Vechiato Filho, Aljomar José; Dos Santos, Daniela Micheline; da Silva, Emily Vivianne Freitas; Goiato, Marcelo Coelho

    2016-10-01

    Different factors can influence marginal bone loss around dental implants, including the type of internal and external connection between the implant and the abutment. The evidence needed to evaluate these factors is unclear. The purpose of this systematic review was to evaluate marginal bone loss by radiographic analysis around dental implants with internal or external connections. A systematic review was conducted following the criteria defined by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Initially, a population, intervention, comparison, and outcome(s) (PICO) question was defined: does the connection type (internal or external) influence marginal bone loss in patients undergoing implantation? An electronic search of PubMed/MEDLINE and Scopus databases was performed for studies in English language published between January 2000 and December 2014 by 2 independent reviewers, who analyzed the marginal bone loss of dental implants with an internal and/or external connection. From an initial screening yield of 595 references and after considering inclusion and exclusion criteria, 17 articles were selected for this review. Among them, 10 studies compared groups of implants with internal and external connections; 1 study evaluated external connections; and 6 studies analyzed internal connections. A total of 2708 implants were placed in 864 patients. Regarding the connection type, 2347 implants had internal connections, and 361 implants had external connections. Most studies showed lower marginal bone loss values for internal connection implants than for external connection implants. Osseointegrated dental implants with internal connections exhibited lower marginal bone loss than implants with external connections. This finding is mainly the result of the platform switching concept, which is more frequently found in implants with internal connections. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry

  12. Regional Externalities

    NARCIS (Netherlands)

    Heijman, W.J.M.

    2007-01-01

    The book offers practical and theoretical insights in regional externalities. Regional externalities are a specific subset of externalities that can be defined as externalities where space plays a dominant role. This class of externalities can be divided into three categories: (1) externalities

  13. Leaflet manual of external beam radiation therapy for hepatocellular carcinoma: a review of the indications, evidences, and clinical trials.

    Science.gov (United States)

    Rim, Chai Hong; Yoon, Won Sup

    2018-01-01

    The use of external beam radiation therapy (EBRT) in the treatment of hepatocellular carcinoma (HCC), which was rarely performed due to liver toxicity with a previous technique, has increased. Palliation of portal vein thrombosis, supplementation for insufficient transarterial chemoembolization, and provision of new curative opportunities using stereotactic body radiotherapy are the potential indications for use of EBRT. The mechanism of EBRT treatment, with its radiobiological and physical perspectives, differs from those of conventional medical treatment or surgery. Therefore, understanding the effects of EBRT may be unfamiliar to physicians other than radiation oncologists, especially in the field of HCC, where EBRT has recently begun to be applied. The first objective of this review was to concisely explain the indications for use of EBRT for HCC for all physicians treating HCC. Therefore, this review focuses on the therapeutic outcomes rather than the detailed biological and physical background. We also reviewed recent clinical trials that may extend the indications for use of EBRT. Finally, we reviewed the current clinical practice guidelines for the treatment of HCC and discuss the current recommendations and future perspectives.

  14. Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study

    NARCIS (Netherlands)

    Onland, Wes; Debray, Thomas P.; Laughon, Matthew M.; Miedema, Martijn; Cools, Filip; Askie, Lisa M.; Asselin, Jeanette M.; Calvert, Sandra A.; Courtney, Sherry E.; Dani, Carlo; Durand, David J.; Marlow, Neil; Peacock, Janet L.; Pillow, J. Jane; Soll, Roger F.; Thome, Ulrich H.; Truffert, Patrick; Schreiber, Michael D.; van Reempts, Patrick; Vendettuoli, Valentina; Vento, Giovanni; van Kaam, Anton H.; Moons, Karel G.; Offringa, Martin

    2013-01-01

    Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth. Very different models using clinical parameters at an early postnatal age to predict BPD have been developed with little extensive quantitative validation. The objective of this study is to review and validate clinical

  15. 77 FR 36534 - Third External Review Draft Integrated Science Assessment for Ozone and Related Photochemical...

    Science.gov (United States)

    2012-06-19

    ... which, among other things, ``cause or contribute to air pollution which may reasonably be anticipated to... Clean Air Act, is charged (among other things) with independent scientific review of EPA's air quality..., such as copyrighted material, are publicly available only in hard copy. Publicly available docket...

  16. External Quality Control Review of the Defense Information Systems Agency Audit Organization

    Science.gov (United States)

    2012-08-07

    We are providing this report for your information and use. We have reviewed the system of quality control for the audit organization of the Defense...audit organization encompasses the audit organization’s leadership, emphasis on performing high quality work, and policies and procedures established

  17. Health impact of external funding for HIV, tuberculosis and malaria: systematic review

    NARCIS (Netherlands)

    Jongh, T.E. de; Harnmeijer, J.H.; Atun, R.; Korenromp, E.L.; Zhao, J.; Puvimanasinghe, J.; Baltussen, R.M.P.M.

    2014-01-01

    BACKGROUND: Since 2002, development assistance for health has substantially increased, especially investments for HIV, tuberculosis (TB) and malaria control. We undertook a systematic review to assess and synthesize the existing evidence in the scientific literature on the health impacts of these

  18. Health impact of external funding for HIV, tuberculosis and malaria: Systematic review

    NARCIS (Netherlands)

    T.E. De Jongh (Thyra E.); J.H. Harnmeijer (Joanne H.); R. Atun (Rifat); E.L. Korenromp (Eline); J. Zhao (Jinkou); J.P.A. Puvimanasinghe (John); R.M.P.M. Baltussen (Rob)

    2014-01-01

    textabstractBackground Since 2002, development assistance for health has substantially increased, especially investments for HIV, tuberculosis (TB) and malaria control. We undertook a systematic review to assess and synthesize the existing evidence in the scientific literature on the health impacts

  19. Basins 4.0 Climate Assessment Tool (Cat): Supporting Documentation and User Manual (External Review Draft)

    Science.gov (United States)

    EPA has released of the draft document solely for the purpose of pre-dissemination peer review under applicable Information Quality Guidelines (IQGs). This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agenc...

  20. A Review on the Cosmeceutical and External Applications of Nigella sativa

    Directory of Open Access Journals (Sweden)

    Ahmad M. Eid

    2017-01-01

    Full Text Available It is estimated by the World Health Organization (WHO that most of the world’s population depends on herbal medicine for their health care. Nigella sativa (N. sativa, also known as black-caraway and as “Kalonji,” is a well-known seed all over the world. It is one of the most common medicinal plants worldwide and contains many useful chemical constituents that we can find in its fixed oil, such as thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellimine, nigellicine, nigellidine, and alpha-hederin. Due to these numerous important ingredients it was found that it affects different areas of our body and has many pharmacological effects as antibacterial, antiviral, anti-inflammatory, and wound healing effect and also for acne vulgaris, skin cancer, pigmentation, and many cosmeceutical applications. Based on the folklore usage of N. sativa seeds and oil, they are used in various systems of food and medicines. The aim of this article is to provide a detailed survey of the literature of cosmeceutical and external applications of N. sativa which is expected to stimulate further studies on this subject.

  1. External Application of Traditional Chinese Medicine for Venous Ulcers: A Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Xin Li

    2015-01-01

    Full Text Available Objective. To evaluate the effectiveness of external application of traditional Chinese medicine (EA-TCM on venous ulcers. Methods. Seven databases were searched until April 2015 for randomized controlled trials (RCTs of EA-TCM for venous ulcers. Risk of bias was assessed using Cochrane Handbook guidelines. Study outcomes were presented as risk ratios (RRs for dichotomous data or mean differences (MDs for continuous data. Results. Sixteen of 193 potentially relevant trials met the inclusion criteria; however, their methodological qualities were low. Comparison of the same intervention strategies revealed significant differences in total effectiveness rates between EA-TCM and conventional therapy groups (RR = 1.22, 95% confidence interval [CI] = 1.16–1.29, and P<0.00001. Compared to conventional therapy, EA-TCM combined with conventional therapy had a superior total effectiveness rate (RR = 1.11, 95% CI = 1.04–1.19, and P=0.003. There were no significant differences in recurrence rates during followup and final pain measurements between the experimental and those in the control groups (RR = 0.86, 95% CI = 0.31–2.39, and P=0.85; MD −0.75, 95% CI = −2.15–0.65, and P=0.29. Conclusion. The evidence that EA-TCM is an effective treatment for venous ulcers is encouraging, but not conclusive due to the low methodological quality of the RCTs. Therefore, more high-quality RCTs with larger sample sizes are required.

  2. Preservation of the External Jugular Vein in Bilateral Radical Neck Dissections: Technique in Two Cases and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Rodrigo Lima Bastos da Rocha

    2015-01-01

    Full Text Available Context. The possibility of cephalic venous hypertension with the resultant facial edema and elevated cerebrospinal fluid pressure continues to challenge head and neck surgeons who perform bilateral radical neck dissections during simultaneous or staged procedures. Case Report. The staged procedure in patients who require bilateral neck dissections allows collateral venous drainage to develop, mainly through the internal and external vertebral plexuses, thereby minimizing the risks of deleterious consequences. Nevertheless, this procedure has disadvantages, such as a delay in definitive therapy, the need for a second hospitalization and anesthesia, and the risk of cutting lymphatic vessels and spreading viable cancer cells. In this paper, we discuss the rationale and feasibility of preserving the external jugular vein. Considering the limited number of similar reports in the literature, two cases in which this procedure was accomplished are described. The relevant anatomy and technique are reviewed and the patients’ outcomes are discussed. Conclusion. Preservation of the EJV during bilateral neck dissections is technically feasible, fast, and safe, with clinically and radiologically demonstrated patency.

  3. [Using new media for online consensus conferences and open external review of guidelines - results of two pilot studies].

    Science.gov (United States)

    Nast, Alexander; Rosumeck, Stefanie; Sporbeck, Birte; Rzany, Berthold

    2012-01-01

    The development of guidelines almost always requires considerable time and financial resources. An important task is therefore to identify and evaluate online methods that facilitate guideline work. ONLINE CONSENSUS CONFERENCE: During the development of the S2k guideline for the management of staphylococcus aureus infections an online consensus conference was held using an online tool provided by the Deutsche Forschungsnetz in combination with a telephone conference. During the 2-hour meeting, no technical difficulties occurred. A survey among the participants showed that this format had a high rate of acceptance. ONLINE REVIEW: During the development of the update of the German S3-Guidelines for the therapy of psoriasis an external open review was performed. An online platform allowing direct visible commenting was chosen. During the five week period of commenting, 26 users added 160 comments. After the review process, the comments were assessed by the editors and the original authors. The selected instrument provides a suitable means for online commenting of guidelines and facilitates the revision of the text. Copyright © 2012. Published by Elsevier GmbH.

  4. Lessons Learned from an External Review of the Savannah River Site Saltstone Performance Assessment Program

    International Nuclear Information System (INIS)

    Cook, J.R.

    2006-01-01

    The Savannah River National Laboratory is actively working on a total revision of the Saltstone Performance Assessment. 'Lessons Learned' from the review are being applied to this effort. Examples of the areas in which significant new work is being done are development of a methodology to do probabilistic uncertainty analyses, employing quantitative analytical tools to represent long-term chemical degradation of both concrete and the Saltstone wasteform, and then using those tools to come to a better understanding of how changes in the vault and Saltstone will affect the performance of the overall disposal system over long periods of time. (authors)

  5. Significance of mineralogy in the development of flowsheets for processing uranium ores

    International Nuclear Information System (INIS)

    1980-01-01

    This report has been prepared from material developed at and subsequent to a consultants' meeting held in Vienna in January 1978. The main purpose of the meeting was to prepare a document in the form of a guide for planning and developing treatment flowsheets for uranium ore processing. It was apparent that ore mineralogy, analysed, described and interpreted in ways most meaningful to the metallurgist, is the most essential information required for forming the basis of such planning. This topic, here termed metallurgical mineralogy, is therefore a major theme of this publication. In preparing the report the Agency has borne in mind the important need to impart the experience and knowledge gained in the more developed countries to those who are in the early stages of exploiting their uranium resources. The contents may be criticized as lacking, in some respects, the requisite depth and detail of treatment. The Agency and the consultants are conscious of the need to expand the information in a number of ways. However, the report is presented in its present form in the belief that, as the first attempt to correlate, on a world-wide basis, ore type with processing, it will be considered as a useful basis for future development of these themes

  6. Towards an optimized flow-sheet for a SANEX demonstration process using centrifugal contactors

    International Nuclear Information System (INIS)

    Magnusson, D.; Christiansen, B.; Glatz, J.P.; Malmbeck, R.; Serrano-Purroy, D.; Modolo, G.; Sorel, C.

    2008-01-01

    The design of an efficient process flow-sheet requires accurate extraction data for the experimental set-up used. Often this data is provided as equilibrium data. Due to the small hold-up volume compared to the flow rate in centrifugal contactors the time for extraction is often too short to reach the equilibrium D-ratios. In this work single stage kinetics experiments have been carried out to investigate the D-ratio dependence of the flow rate and also to compare with equilibrium batch experiments for CyMe 4 - BTBP. The first centrifuge experiment was run with spiked solutions while in the second a genuine actinide/lanthanide fraction from a TODGA process was used. Three different flow rates were tested with each set-up. The results show that even with low flow rates, around 8% of the equilibrium D-ratio (Am) was reached for the extraction in the spiked test and around 16% in the hot test (the difference is due to the size of the centrifuges). The general conclusion is that the development of a process flow sheet needs investigation of the kinetic behaviour in the actual equipment used. (authors)

  7. Defense Waste Processing Facility Nitric- Glycolic Flowsheet Chemical Process Cell Chemistry: Part 2

    Energy Technology Data Exchange (ETDEWEB)

    Zamecnik, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-06-06

    The conversions of nitrite to nitrate, the destruction of glycolate, and the conversion of glycolate to formate and oxalate were modeled for the Nitric-Glycolic flowsheet using data from Chemical Process Cell (CPC) simulant runs conducted by Savannah River National Laboratory (SRNL) from 2011 to 2016. The goal of this work was to develop empirical correlation models to predict these values from measureable variables from the chemical process so that these quantities could be predicted a-priori from the sludge or simulant composition and measurable processing variables. The need for these predictions arises from the need to predict the REDuction/OXidation (REDOX) state of the glass from the Defense Waste Processing Facility (DWPF) melter. This report summarizes the work on these correlations based on the aforementioned data. Previous work on these correlations was documented in a technical report covering data from 2011-2015. This current report supersedes this previous report. Further refinement of the models as additional data are collected is recommended.

  8. An analysis of alternative New Technical Strategy flowsheets for tank waste remediation system

    International Nuclear Information System (INIS)

    Booker, C.P.

    1994-01-01

    The Hanford Tank remediation plans have gone through a few revisions for the best waste processing system. Some designs have been complex while others have been fairly simple. One of the key means in understanding and selecting among the various proposed systems is a discrete events modeling of the system. This modeling provides insight into (1) The total required size of the system; (2) The amount of material, such as reagents and other added materials that must be supplied; (3) The final mass of waste that must be stored; and (4) Areas within the system where a small change can greatly effect the total system. Discrete events modeling also provides the means by which various proposed systems may be compared. It is the framework in which variations within a particular system may be explored and compared to other instantiations. This study examines the current New Technical Strategy flowsheet system with discrete event modeling. Some of the possible variations within that system are examined and compared. Further, an previously proposed, more complex system is examined

  9. Physical activity promotion in Latin American populations: a systematic review on issues of internal and external validity.

    Science.gov (United States)

    Galaviz, Karla I; Harden, Samantha M; Smith, Erin; Blackman, Kacie Ca; Berrey, Leanna M; Mama, Scherezade K; Almeida, Fabio A; Lee, Rebecca E; Estabrooks, Paul A

    2014-06-17

    The purpose of this review was to determine the degree to which physical activity interventions for Latin American populations reported on internal and external validity factors using the RE-AIM framework (reach & representativeness, effectiveness, adoption, implementation, maintenance). We systematically identified English (PubMed; EbscoHost) and Spanish (SCIELO; Biblioteca Virtual en Salud) language studies published between 2001 and 2012 that tested physical activity, exercise, or fitness promotion interventions in Latin American populations. Cross-sectional/descriptive studies, conducted in Brazil or Spain, published in Portuguese, not including a physical activity/fitness/exercise outcome, and with one time point assessment were excluded. We reviewed 192 abstracts and identified 46 studies that met the eligibility criteria (34 in English, 12 in Spanish). A validated 21-item RE-AIM abstraction tool was used to determine the quality of reporting across studies (0-7 = low, 8-14 = moderate, and 15-21 = high). The number of indicators reported ranged from 3-14 (mean = 8.1 ± 2.6), with the majority of studies falling in the moderate quality reporting category. English and Spanish language articles did not differ on the number of indicators reported (8.1 vs. 8.3, respectively). However, Spanish articles reported more across reach indicators (62% vs. 43% of indicators), while English articles reported more across effectiveness indicators (69% vs 62%). Across RE-AIM dimensions, indicators for reach (48%), efficacy/effectiveness (67%), and implementation (41%) were reported more often than indicators of adoption (25%) and maintenance (10%). Few studies reported on the representativeness of participants, staff that delivered interventions, or the settings where interventions were adopted. Only 13% of the studies reported on quality of life and/or potential negative outcomes, 20% reported on intervention fidelity, and 11% on cost of implementation

  10. Review of SKB's Safety Assessment SR-Can: Contributions in Support of SKI's and SSI's Review by External Consultants

    Energy Technology Data Exchange (ETDEWEB)

    2008-03-15

    The Swedish Nuclear Fuel and Waste Management Co (SKB) plans to submit a license application for the construction of a repository for spent nuclear fuel in Sweden 2010. In support of this application SKB will present a safety report, SR-Site, on the repository's long-term safety and radiological consequences. As a preparation for SR-Site, SKB published the preliminary safety assessment SR-Can in November 2006. The purposes were to document a first evaluation of long-term safety for the two candidate sites at Forsmark and Laxemar and to provide feedback to SKB's future programme of work. An important objective of the authorities' review of SR-Can is to provide guidance to SKB on the complete safety reporting for the license application. The authorities have engaged external experts for independent modelling, analysis and review, with the aim to provide a range of expert opinions related to the sufficiency and appropriateness of various aspects of SR-Can. The conclusions and judgments in this report are those of the authors and may not necessarily coincide with those of SKI and SSI. The authorities own review will be published separately (SKI Report 2008:23, SSI Report 2008:04 E). This report compiles contributions from several specific research projects. The separate reviews cover topics regarding the engineered barrier system, the quality assurance, the climate evolution and its effects, and the ecosystems and environmental impacts. All contributions are in English apart from the review concerning ecosystems and environmental impacts, which is presented in Swedish

  11. Report for Treating Hanford LAW and WTP SW Simulants: Pilot Plant Mineralizing Flowsheet

    International Nuclear Information System (INIS)

    Olson, Arlin

    2012-01-01

    The US Department of Energy is responsible for managing the disposal of radioactive liquid waste in underground storage tanks at the Hanford site in Washington State. The Hanford waste treatment and immobilization plant (WPT) will separate the waste into a small volume of high level waste (HLW), containing most of the radioactive constituents, and a larger volume of low activity waste (LAW), containing most of the non-radioactive chemical and hazardous constituents. The HLW and LAW will be converted into immobilized waste forms for disposal. Currently there is inadequate LAW vitrification capacity planned at the WTP to complete the mission within the required timeframe. Therefore additional LAW capacity is required. One candidate supplemental treatment technology is the fluidized bed steam reformer process (FBSR). This report describes the demonstration testing of the FBSR process using a mineralizing flowsheet for treating simulated Hanford LAW and secondary waste from the WTP (WTP SW). The FBSR testing project produced leach-resistant solid products and environmentally compliant gaseous effluents. The solid products incorporated normally soluble ions into an alkali alumino-silicate (NaS) mineral matrix. Gaseous emissions were found to be within regulatory limits. Cesium and rhenium were captured in the mineralized products with system removal efficiencies of 99.999% and 99.998 respectively. The durability and leach performance of the FBSR granular solid were superior to the low activity reference material (LMR) glass standards. Normalized product consistency test (PCT) release rates for constituents of concern were approximately 2 orders of magnitude less than that of sodium in the Hanford glass [standard].

  12. Report for Treating Hanford LAW and WTP SW Simulants: Pilot Plant Mineralizing Flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    Arlin Olson

    2012-02-28

    The US Department of Energy is responsible for managing the disposal of radioactive liquid waste in underground storage tanks at the Hanford site in Washington State. The Hanford waste treatment and immobilization plant (WPT) will separate the waste into a small volume of high level waste (HLW), containing most of the radioactive constituents, and a larger volume of low activity waste (LAW), containing most of the non-radioactive chemical and hazardous constituents. The HLW and LAW will be converted into immobilized waste forms for disposal. Currently there is inadequate LAW vitrification capacity planned at the WTP to complete the mission within the required timeframe. Therefore additional LAW capacity is required. One candidate supplemental treatment technology is the fluidized bed steam reformer process (FBSR). This report describes the demonstration testing of the FBSR process using a mineralizing flowsheet for treating simulated Hanford LAW and secondary waste from the WTP (WTP SW). The FBSR testing project produced leach-resistant solid products and environmentally compliant gaseous effluents. The solid products incorporated normally soluble ions into an alkali alumino-silicate (NaS) mineral matrix. Gaseous emissions were found to be within regulatory limits. Cesium and rhenium were captured in the mineralized products with system removal efficiencies of 99.999% and 99.998 respectively. The durability and leach performance of the FBSR granular solid were superior to the low activity reference material (LMR) glass standards. Normalized product consistency test (PCT) release rates for constituents of concern were approximately 2 orders of magnitude less than that of sodium in the Hanford glass [standard].

  13. Regional variation in breast cancer treatment in the Netherlands and the role of external peer review : a cohort study comprising 63,516 women

    NARCIS (Netherlands)

    Kilsdonk, Melvin J.; van Dijk, Boukje A. C.; Otter, Renee; van Harten, Wim H.; Siesling, Sabine

    2014-01-01

    Background: Treatment variation is an important issue in health care provision. An external peer review programme for multidisciplinary cancer care was introduced in 1994 in the Netherlands to improve the multidisciplinary organisation of cancer care in hospitals. So far the clinical impact of

  14. Central Neuraxial Blockade-Assisted External Cephalic Version in Reducing Caesarean Section Rate: Systematic Review and Meta-Analysis

    Science.gov (United States)

    Bolaji, Ibrahim; Alabi-Isama, Lillian

    2009-01-01

    We review the medical literature on the success, safety and economic value of central neuraxial blockade-assisted (CNB) external cephalic version from randomized controlled studies identified from 1951 to 2009. The result showed that more women had successful ECV with regional anaesthesia with corresponding reduction in caesarean section rate. They were 1.5 times more likely than women not receiving anaesthesia to have a successful ECV. The number to treat is six women needed to receive anaesthesia for 1 baby to be turned from breech to cephalic presentation. Feto-maternal morbidity was not increased in the CNB-aided group consisting of only transient bradycardia. Although the appropriate amount of force for safe version has not been quantified, there was no report of uterine rupture despite removal of these patients from “excessive force-pain biofeedback loop” induced through motor nerve blockade. We can attribute 30% of cost savings amounting to £42,150.00 directly to CNB using the most up to date Health Resource Group Code (HRG4). The initial results are encouraging but until the benefits and safety of CNB-aided ECV are substantiated by large randomized, blinded controlled trials, this practice cannot be universally recommended. PMID:20069044

  15. Central Neuraxial Blockade-Assisted External Cephalic Version in Reducing Caesarean Section Rate: Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Ibrahim Bolaji

    2009-01-01

    Full Text Available We review the medical literature on the success, safety and economic value of central neuraxial blockade-assisted (CNB external cephalic version from randomized controlled studies identified from 1951 to 2009. The result showed that more women had successful ECV with regional anaesthesia with corresponding reduction in caesarean section rate. They were 1.5 times more likely than women not receiving anaesthesia to have a successful ECV. The number to treat is six women needed to receive anaesthesia for 1 baby to be turned from breech to cephalic presentation. Feto-maternal morbidity was not increased in the CNB-aided group consisting of only transient bradycardia. Although the appropriate amount of force for safe version has not been quantified, there was no report of uterine rupture despite removal of these patients from “excessive force-pain biofeedback loop” induced through motor nerve blockade. We can attribute 30% of cost savings amounting to £42,150.00 directly to CNB using the most up to date Health Resource Group Code (HRG4. The initial results are encouraging but until the benefits and safety of CNB-aided ECV are substantiated by large randomized, blinded controlled trials, this practice cannot be universally recommended.

  16. Decision Making Under Objective Risk Conditions-a Review of Cognitive and Emotional Correlates, Strategies, Feedback Processing, and External Influences.

    Science.gov (United States)

    Schiebener, Johannes; Brand, Matthias

    2015-06-01

    While making decisions under objective risk conditions, the probabilities of the consequences of the available options are either provided or calculable. Brand et al. (Neural Networks 19:1266-1276, 2006) introduced a model describing the neuro-cognitive processes involved in such decisions. In this model, executive functions associated with activity in the fronto-striatal loop are important for developing and applying decision-making strategies, and for verifying, adapting, or revising strategies according to feedback. Emotional rewards and punishments learned from such feedback accompany these processes. In this literature review, we found support for the role of executive functions, but also found evidence for the importance of further cognitive abilities in decision making. Moreover, in addition to reflective processing (driven by cognition), decisions can be guided by impulsive processing (driven by anticipation of emotional reward and punishment). Reflective and impulsive processing may interact during decision making, affecting the evaluation of available options, as both processes are affected by feedback. Decision-making processes are furthermore modulated by individual attributes (e.g., age), and external influences (e.g., stressors). Accordingly, we suggest a revised model of decision making under objective risk conditions.

  17. Effectiveness of external cues to facilitate task performance in people with neurological disorders: a systematic review and meta-analysis.

    Science.gov (United States)

    Harrison, Stephanie L; Laver, Kate E; Ninnis, Kayla; Rowett, Cherie; Lannin, Natasha A; Crotty, Maria

    2018-03-09

    To examine in people with neurological disorders, which method/s of providing external cues to improve task performance are most effective. Medline, EMBASE, and PsycINFO were systematically searched. Two reviewers independently screened, extracted data, and assessed the quality of the evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Twenty six studies were included. Studies examined a wide-range of cues including visual, tactile, auditory, verbal, and multi-component cues. Cueing (any type) improved walking speed when comparing cues to no cues (mean difference (95% confidence interval): 0.08 m/s (0.06-0.10), I 2  = 68%, low quality of evidence). Remaining evidence was analysed narratively; evidence that cueing improves activity-related outcomes was inconsistent and rated as very low quality. It was not possible to determine which form of cueing may be more effective than others. Providing cues to encourage successful task performance is a core component of rehabilitation, however there is limited evidence on the type of cueing or which tasks benefit most from external cueing. Low-quality evidence suggests there may be a beneficial effect of cueing (any type) on walking speed. Sufficiently powered randomised controlled trials are needed to inform therapists of the most effective cueing strategies to improve activity performance in populations with a neurological disorder. Implications for rehabilitation Providing cues is a core component of rehabilitation and may improve successful task performance and activities in people with neurological conditions including stroke, Parkinson's disease, Alzheimer's disease, traumatic brain injury, and multiple sclerosis, but evidence is limited for most neurological conditions with much research focusing on stroke and Parkinson's disease. Therapists should consider using a range of different types of cues depending on the aims of treatment and the neurological condition. There is

  18. GLYCOLIC-NITRIC ACID FLOWSHEET DEMONSTRATION OF THE DWPF CHEMICAL PROCESSING CELL WITH MATRIX SIMULANTS AND SUPERNATE

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, D.; Stone, M.; Newell, J.; Best, D.

    2012-05-07

    Savannah River Remediation (SRR) is evaluating changes to its current DWPF flowsheet to improve processing cycle times. This will enable the facility to support higher canister production while maximizing waste loading. Higher throughput is needed in the CPC since the installation of the bubblers into the melter has increased melt rate. Due to the significant maintenance required for the DWPF gas chromatographs (GC) and the potential for production of flammable quantities of hydrogen, reducing or eliminating the amount of formic acid used in the CPC is being developed. Earlier work at Savannah River National Laboratory has shown that replacing formic acid with an 80:20 molar blend of glycolic and formic acids has the potential to remove mercury in the SRAT without any significant catalytic hydrogen generation. This report summarizes the research completed to determine the feasibility of processing without formic acid. In earlier development of the glycolic-formic acid flowsheet, one run (GF8) was completed without formic acid. It is of particular interest that mercury was successfully removed in GF8, no formic acid at 125% stoichiometry. Glycolic acid did not show the ability to reduce mercury to elemental mercury in initial screening studies, which is why previous testing focused on using the formic/glycolic blend. The objective of the testing detailed in this document is to determine the viability of the nitric-glycolic acid flowsheet in processing sludge over a wide compositional range as requested by DWPF. This work was performed under the guidance of Task Technical and Quality Assurance Plan (TT and QAP). The details regarding the simulant preparation and analysis have been documented previously.

  19. GLYCOLIC-NITRIC ACID FLOWSHEET DEMONSTRATION OF THE DWPF CHEMICAL PROCESS CELL WITH SLUDGE AND SUPERNATE SIMULANTS

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, D.; Stone, M.; Newell, J.; Best, D.; Zamecnik, J.

    2012-08-28

    Savannah River Remediation (SRR) is evaluating changes to its current Defense Waste Processing Facility (DWPF) flowsheet to improve processing cycle times. This will enable the facility to support higher canister production while maximizing waste loading. Higher throughput is needed in the Chemical Process Cell (CPC) since the installation of the bubblers into the melter has increased melt rate. Due to the significant maintenance required for the DWPF gas chromatographs (GC) and the potential for production of flammable quantities of hydrogen, reducing or eliminating the amount of formic acid used in the CPC is being developed. Earlier work at Savannah River National Laboratory has shown that replacing formic acid with an 80:20 molar blend of glycolic and formic acids has the potential to remove mercury in the SRAT without any significant catalytic hydrogen generation. This report summarizes the research completed to determine the feasibility of processing without formic acid. In earlier development of the glycolic-formic acid flowsheet, one run (GF8) was completed without formic acid. It is of particular interest that mercury was successfully removed in GF8, no formic acid at 125% stoichiometry. Glycolic acid did not show the ability to reduce mercury to elemental mercury in initial screening studies, which is why previous testing focused on using the formic/glycolic blend. The objective of the testing detailed in this document is to determine the viability of the nitric-glycolic acid flowsheet in processing sludge over a wide compositional range as requested by DWPF. This work was performed under the guidance of Task Technical and Quality Assurance Plan (TT&QAP). The details regarding the simulant preparation and analysis have been documented previously.

  20. Flowsheet development studies for the decontamination of high-activity-level water at Three Mile Island Unit 2

    International Nuclear Information System (INIS)

    Collins, E.D.; Bigelow, J.E.; Campbell, D.O.; King, L.J.; Knauer, J.B.

    1980-01-01

    Several chemical processing flowsheets were considered for the decontamination of high-activity-level water at the Three Mile Island (TMI) Unit 2. A zeolite ion exchange process was evaluated and recommended for absorption of the bulk of the highly radioactive cesium and strontium. Standard organic ion-exchange resins were selected to remove the remaining traces of radioactive nuclides (except tritium which cannot be removed by any practical process). Process conditions were evaluated using both synthetic, tracer-level solutions and samples of actual, high-activity level water from TMI Unit 2

  1. Design of preconcentration flow-sheet for processing Bhimunipatnam beach sands using pilot plant experiments and computer simulation

    International Nuclear Information System (INIS)

    Padmanabhan, N.P.H.; Sridhar, U.

    1993-01-01

    Simulation was carried out using a beach sand beneficiation plant simulator software, SANDBEN, currently being developed in Indian School of Mines, Dhanbad, and the results were compared and analyzed with those obtained by actual pilot plant experiments on a beach sand sample from Bhimunipatnam deposit. The software is discussed and its capabilities and limitations are highlighted. An optimal preconcentrator flow-sheet for processing Bhimunipatnam beach sand was developed by simulation and using the results of the pilot plant experiments. (author). 13 refs., 2 tabs., 3 figs

  2. The effectiveness of external sensory cues in improving functional performance in individuals with Parkinson's disease: a systematic review with meta-analysis.

    Science.gov (United States)

    Cassimatis, Constantine; Liu, Karen P Y; Fahey, Paul; Bissett, Michelle

    2016-09-01

    A systematic review with meta-analysis was performed to investigate the effect external sensory cued therapy on activities of daily living (ADL) performance that include walking and daily tasks such as dressing for individuals with Parkinson's disease (PD). A detailed computer-aided search of the literature was applied to MEDLINE, Cumulative Index to Nursing and Allied Health Literature, EMBASE and PubMed. Studies investigating the effects of external sensory cued therapy on ADL performance for individuals with PD in all stages of disease progression were collected. Relevant articles were critically reviewed and study results were synthesized by two independent researchers. A data-analysis method was used to extract data from selected articles. A meta-analysis was carried out for all randomized-controlled trials. Six studies with 243 individuals with PD were included in this review. All six studies yielded positive findings in favour of external sensory cues. The meta-analysis showed that external sensory cued therapy improved statistically after treatment (P=0.011) and at follow-up (Psensory into a training programme focused on improving daily task performance.

  3. Bilateral External Auditory Exostoses Causing Conductive Hearing Loss: A Case Report and Literature Review of the Surfer's Ear.

    Science.gov (United States)

    Barbon, Dennis A; Hegde, Rahul; Li, Shuo; Abdelbaki, Ahmed; Bajaj, Divyansh

    2017-10-30

    In patients with repeated exposure to cold water, such as cold water surfers and kayakers, the reactive exostoses can occur in the external auditory canal. The external auditory canal exostoses are multiple, benign bony growths. They can cause external auditory canal stenosis, leading to repeated otitis externa and potentially conductive hearing loss. It is vital to consider this entity in susceptible patients who report hearing loss, as timely intervention such as proper ear protection equipment can lower the risk of developing severe external auditory canal exostoses. We present a case of a 42-year-old male, cold water surfer with conductive hearing loss and bilateral external auditory canal (EAC) stenosis demonstrated on the computed tomography.

  4. A qualitative systematic review of internal and external influences on shared decision-making in all health care settings.

    Science.gov (United States)

    Truglio-Londrigan, Marie; Slyer, Jason T; Singleton, Joanne K; Worral, Priscilla

    The objective of this review is to identify and synthesize the best available evidence related to the meaningfulness of internal and external influences on shared-decision making for adult patients and health care providers in all health care settings.The specific questions to be answered are: BACKGROUND: Patient-centered care is emphasized in today's healthcare arena. This emphasis is seen in the works of the International Alliance of Patients' Organizations (IAOP) who describe patient-centered healthcare as care that is aimed at addressing the needs and preferences of patients. The IAOP presents five principles which are foundational to the achievement of patient-centered healthcare: respect, choice, policy, access and support, as well as information. These five principles are further described as:Within the description of these five principles the idea of shared decision-making is clearly evident.The concept of shared decision-making began to appear in the literature in the 1990s. It is defined as a "process jointly shared by patients and their health care provider. It aims at helping patients play an active role in decisions concerning their health, which is the ultimate goal of patient-centered care." The details of the shared decision-making process are complex and consist of a series of steps including:Three overall representative decision-making models are noted in contemporary literature. These three models include: paternalistic, informed decision-making, and shared decision-making. The paternalistic model is an autocratic style of decision-making where the healthcare provider carries out the care from the perspective of knowing what is best for the patient and therefore makes all decisions. The informed decision-making model takes place as the information needed to make decisions is conveyed to the patient and the patient makes the decisions without the healthcare provider involvement. Finally, the shared decision-making model is representative of a

  5. External cephalic version among women with a previous cesarean delivery: report on 36 cases and review of the literature.

    Science.gov (United States)

    Abenhaim, Haim A; Varin, Jocelyne; Boucher, Marc

    2009-01-01

    Whether or not women with a previous cesarean section should be considered for an external cephalic version remains unclear. In our study, we sought to examine the relationship between a history of previous cesarean section and outcomes of external cephalic version for pregnancies at 36 completed weeks of gestation or more. Data on obstetrical history and on external cephalic version outcomes was obtained from the C.H.U. Sainte-Justine External Cephalic Version Database. Baseline clinical characteristics were compared among women with and without a history of previous cesarean section. We used logistic regression analysis to evaluate the effect of previous cesarean section on success of external cephalic version while adjusting for parity, maternal body mass index, gestational age, estimated fetal weight, and amniotic fluid index. Over a 15-year period, 1425 external cephalic versions were attempted of which 36 (2.5%) were performed on women with a previous cesarean section. Although women with a history of previous cesarean section were more likely to be older and para >2 (38.93% vs. 15.0%), there were no difference in gestational age, estimated fetal weight, and amniotic fluid index. Women with a prior cesarean section had a success rate similar to women without [50.0% vs. 51.6%, adjusted OR: 1.31 (0.48-3.59)]. Women with a previous cesarean section who undergo an external cephalic version have similar success rates than do women without. Concern about procedural success in women with a previous cesarean section is unwarranted and should not deter attempting an external cephalic version.

  6. Enhanced external counterpulsation for the treatment of stable angina and heart failure: a systematic review and economic analysis.

    Science.gov (United States)

    McKenna, C; McDaid, C; Suekarran, S; Hawkins, N; Claxton, K; Light, K; Chester, M; Cleland, J; Woolacott, N; Sculpher, M

    2009-04-01

    To determine the clinical effectiveness and cost-effectiveness of enhanced external counterpulsation (EECP) compared with usual care and placebo for refractory stable angina and heart failure, and to undertake analyses of the expected value of information to assess the potential value of future research on EECP. Major electronic databases were searched between November 2007 and March 2008. A systematic review of the literature was undertaken and a decision model developed to compare EECP treatment with no treatment in adults with chronic stable angina. Five studies were included in the review. In the Multicenter Study of Enhanced External Counterpulsation (MUST-EECP), time to greater than or equal to 1-mm ST segment depression (exercise-induced ischaemia) was statistically significantly improved in the EECP group compared with the control group (sham EECP), mean difference (MD) 41 seconds [95% confidence interval (CI) 9.10-73.90]. However, there was no statistically significant difference between the EECP and control groups in the change in exercise duration from baseline to end of treatment, self-reported angina episodes or daily nitroglycerin use, and the clinical significance of the limited benefits was unclear. There was also a lack of data on long-term outcomes. There were more withdrawals due to adverse events in the EECP group than in the control group, as well as a greater proportion of patients with adverse events [relative risk (RR) 2.13, 95% CI 1.35-3.38]. The three non-randomised studies compared EECP with elective percutaneous coronary intervention (PCI) and usual care. There was a high risk of selection bias in all three studies and the results should be treated with considerable caution. The study comparing an EECP registry with a PCI registry reported similar 1-year all-cause mortality in both groups. In the Prospective Evaluation of EECP in Congestive Heart Failure (PEECH) trial, patients with heart failure were randomised to EECP or to usual care

  7. Internalizing environmental costs: A survey of progress in estimating the external environmental costs of electricity production and a review of market-based policies to incorporate them

    International Nuclear Information System (INIS)

    Eto, J.H.; Helcke, G.

    1991-01-01

    The production of electricity creates environmental insults whose costs are not fully reflected in the prices paid by consumers for electricity services. Failure to incorporate these external costs leads to economically inefficient production and consumption decisions. The present work reviews two related efforts to address this market distortion. The first concerns progress in estimating the uninternalized environmental costs of electricity production. The second concerns market-based approaches to internalizing these costs in electricity production and consumption decisions. 10 tabs.; 41 refs

  8. International Expert Review of SRCan: Engineered Barrier Issues. External review contribution in support of SKI's and SSI's review of SR-Can

    International Nuclear Information System (INIS)

    Savage, David; Bennett, David; Apted, Mick; Saellfors, Goeran; Saario, Timo; Segle, Peter

    2008-03-01

    The Swedish Nuclear Fuel and Waste Management Company (SKB) has recently submitted a license application for the construction of a spent fuel encapsulation plant. SKB plans to submit a further license application in 2009 for the construction of a repository for the disposal spent nuclear fuel. In connection with the first of these applications, SKB published a safety report, known as SR-Can, which assessed the safety of a spent-fuel repository. The Swedish Nuclear Power Inspectorate (SKI) and the Swedish Radiation Protection Authority (SSI) (the Authorities) will make formal reviews of the licence applications, and have, therefore, jointly commissioned a team of independent experts to assess and provide comments on SKB's safety reports. The Authorities will consider the views of the independent review team in completing their own reviews. This document presents the comments and findings of the Engineered Barrier System (EBS) review group on SR-Can. The SR-Can safety report includes an examination of EBS design and performance for a range of scenarios, including expected repository evolution and possible variant scenarios, that together address processes and events that might result in the loss of certain repository safety functions. Furthermore, a series of sensitivity analyses is also presented that provides helpful insights into the relative importance of many key parameters and processes related to the EBS. In general, the explanatory text of the SR-Can safety report is clear, and the cited references provide adequate technical justifications for the assumptions, models, and data that are abstracted into the SR-Can safety report. The review group considers, therefore, that SKB's development of SR-Can has been a very valuable exercise, and that SKB should be congratulated on the breadth, depth and general clarity of its research and development and safety assessment programmes. Notwithstanding these successes, the EBS review group has identified a range of

  9. International Expert Review of Sr-Can: Safety Assessment Methodology - External review contribution in support of SSI's and SKI's review of SR-Can

    International Nuclear Information System (INIS)

    Sagar, Budhi; Egan, Michael; Roehlig, Klaus-Juergen; Chapman, Neil; Wilmot, Roger

    2008-03-01

    In 2006, SKB published a safety assessment (SR-Can) as part of its work to support a licence application for the construction of a final repository for spent nuclear fuel. The purposes of the SR-Can project were stated in the main project report to be: 1. To make a first assessment of the safety of potential KBS-3 repositories at Forsmark and Laxemar to dispose of canisters as specified in the application for the encapsulation plant. 2. To provide feedback to design development, to SKB's research and development (R and D) programme, to further site investigations and to future safety assessments. 3. To foster a dialogue with the authorities that oversee SKB's activities, i.e. the Swedish Nuclear Power Inspectorate, SKI, and the Swedish Radiation Protection Authority, SSI, regarding interpretation of applicable regulations, as a preparation for the SR-Site project. To help inform their review of SKB's proposed approach to development of the longterm safety case, the authorities appointed three international expert review teams to carry out a review of SKB's SR-Can safety assessment report. Comments from one of these teams - the Safety Assessment Methodology (SAM) review team - are presented in this document. The SAM review team's scope of work included an examination of SKB's documentation of the assessment ('Long-term safety for KBS-3 Repositories at Forsmark and Laxemar - a first evaluation' and several supporting reports) and hearings with SKB staff and contractors, held in March 2007. As directed by SKI and SSI, the SAM review team focused on methodological aspects and sought to determine whether SKB's proposed safety assessment methodology is likely to be suitable for use in the future SR-Site and to assess its consistency with the Swedish regulatory framework. No specific evaluation of long-term safety or site acceptability was undertaken by any of the review teams. SKI and SSI's Terms of Reference for the SAM review team requested that consideration be given

  10. Effect of regional anesthesia on the success rate of external cephalic version: a systematic review and meta-analysis.

    Science.gov (United States)

    Goetzinger, Katherine R; Harper, Lorie M; Tuuli, Methodius G; Macones, George A; Colditz, Graham A

    2011-11-01

    To estimate whether the use of regional anesthesia is associated with increased success of external cephalic version. We searched MEDLINE, EMBASE, the Cochrane Library, and clinical trial registries. Electronic databases were searched from 1966 through April 2011 for published, randomized controlled trials in the English language comparing regional anesthesia with no regional anesthesia for external cephalic version. The primary outcome was external cephalic version success. Secondary outcomes included cesarean delivery, maternal discomfort, and adverse events. Pooled risk ratios (relative risk) were calculated using a random-effects model. Heterogeneity was assessed using the Cochran's Q statistic and quantified using the I Z method. Six randomized controlled trials met criteria for study inclusion. Regional anesthesia was associated with a higher external cephalic version success rate compared with intravenous or no analgesia (59.7% compared with 37.6%; pooled relative risk 1.58; 95% confidence interval [CI] 1.29-1.93). This significant association persisted when the data were stratified by type of regional anesthesia (spinal compared with epidural). The number needed to treat with regional anesthesia to achieve one additional successful external cephalic version was five. There was no evidence of statistical heterogeneity (P=.32, I Z=14.9%) or publication bias (Harbord test P=.78). There was no statistically significant difference in the risk of cesarean delivery comparing regional anesthesia with intravenous or no analgesia (48.4% compared with 59.3%; pooled relative risk 0.80; 95% CI 0.55-1.17). Adverse events were rare and not significantly different between the two groups. Regional anesthesia is associated with a higher success rate of external cephalic version.

  11. International Expert Review of SRCan: Site Investigation Aspects. External review contribution in support of SKI's and SSI's review of SR-Can. INSITE/OVERSITE

    International Nuclear Information System (INIS)

    2008-03-01

    As a first evaluation of long-term safety for KBS-3 repositories at Forsmark and Laxemar, the SIG (Site Investigation Group) found SR-Can to be a well-produced and generally well-argued safety assessment. Overall, SKB is to be complimented on this project. Members of of the two groups INSITE and OVERSITE within the SIG had somewhat differing views on how well SKB had made use of the site data available at the end of the SDM 1.2 stage of investigations. This difference is less to do with the extent of site characterisation than of its use and application, reflecting the different levels of maturity of SKB's geosphere and biosphere assessment programmes. The more recent and current work on the sites means that our concerns expressed in this review should, to a large extent, be addressable in or prior to SR-Site, provided SKB is so minded. However, we acknowledge that some of the issues we raise will not be fully resolved until underground rock characterisation from excavations or longer records of surface conditions are available. There are also some key aspects of SKB's methodology still under development that would benefit from review prior to their use in SR-Site. More space in the currently pressing schedule would allow for this review and a consequent increase in confidence. In any case, the authorities should be aware that SKB may face residual programmatic risks, associated principally with the underground design and layout (and their knockon effects into performance), even after SR-Site. An early understanding of some of these relationships would be helped by a plan (at least on an outline level) of the underground characterisation programme. We also note that many engineering matters are still to be confronted, not least the EBS design and its implementation, along with the treatment of high stresses, if Forsmark is selected. However, our views on the nature of the SR-Can analysis and the way in which site data have been utilised in it (our principal remit

  12. International Expert Review of SRCan: Engineered Barrier Issues. External review contribution in support of SKI's and SSI's review of SR-Can

    Energy Technology Data Exchange (ETDEWEB)

    Savage, David (Quintessa Limited, Henley-on-Thames (GB)); Bennett, David (TerraSalus Limited, Oakham (GB)); Apted, Mick (Monitor Scientific LLC, Denver, CO (US)); Saellfors, Goeran (Chalmers Univ. of Technology, Goeteborg (SE)); Saario, Timo (VTT Materials and Building (FI)); Segle, Peter (Inspecta, Stockholm (SE))

    2008-03-15

    The Swedish Nuclear Fuel and Waste Management Company (SKB) has recently submitted a license application for the construction of a spent fuel encapsulation plant. SKB plans to submit a further license application in 2009 for the construction of a repository for the disposal spent nuclear fuel. In connection with the first of these applications, SKB published a safety report, known as SR-Can, which assessed the safety of a spent-fuel repository. The Swedish Nuclear Power Inspectorate (SKI) and the Swedish Radiation Protection Authority (SSI) (the Authorities) will make formal reviews of the licence applications, and have, therefore, jointly commissioned a team of independent experts to assess and provide comments on SKB's safety reports. The Authorities will consider the views of the independent review team in completing their own reviews. This document presents the comments and findings of the Engineered Barrier System (EBS) review group on SR-Can. The SR-Can safety report includes an examination of EBS design and performance for a range of scenarios, including expected repository evolution and possible variant scenarios, that together address processes and events that might result in the loss of certain repository safety functions. Furthermore, a series of sensitivity analyses is also presented that provides helpful insights into the relative importance of many key parameters and processes related to the EBS. In general, the explanatory text of the SR-Can safety report is clear, and the cited references provide adequate technical justifications for the assumptions, models, and data that are abstracted into the SR-Can safety report. The review group considers, therefore, that SKB's development of SR-Can has been a very valuable exercise, and that SKB should be congratulated on the breadth, depth and general clarity of its research and development and safety assessment programmes. Notwithstanding these successes, the EBS review group has identified a range

  13. Implementation of flowsheet change to minimize hydrogen and ammonia generation during chemical processing of high level waste in the Defense Waste Processing Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, Dan P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Woodham, Wesley H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Williams, Matthew S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Newell, J. David [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Luther, Michelle C. [Auburn Univ., AL (United States); Brandenburg, Clayton H. [Univ.of South Carolina, Columbia, SC (United States)

    2016-09-27

    Testing was completed to develop a chemical processing flowsheet for the Defense Waste Processing Facility (DWPF), designed to vitrify and stabilize high level radioactive waste. DWPF processing uses a reducing acid (formic acid) and an oxidizing acid (nitric acid) to rheologically thin the slurry and complete the necessary acid base and reduction reactions (primarily mercury and manganese). Formic acid reduces mercuric oxide to elemental mercury, allowing the mercury to be removed during the boiling phase of processing through steam stripping. In runs with active catalysts, formic acid can decompose to hydrogen and nitrate can be reduced to ammonia, both flammable gases, due to rhodium and ruthenium catalysis. Replacement of formic acid with glycolic acid eliminates the generation of rhodium- and ruthenium-catalyzed hydrogen and ammonia. In addition, mercury reduction is still effective with glycolic acid. Hydrogen, ammonia and mercury are discussed in the body of the report. Ten abbreviated tests were completed to develop the operating window for implementation of the flowsheet and determine the impact of changes in acid stoichiometry and the blend of nitric and glycolic acid as it impacts various processing variables over a wide processing region. Three full-length 4-L lab-scale simulations demonstrated the viability of the flowsheet under planned operating conditions. The flowsheet is planned for implementation in early 2017.

  14. Poor quality of external validity reporting limits generalizability of overweight and/or obesity lifestyle prevention interventions in young adults: a systematic review.

    Science.gov (United States)

    Partridge, S R; Juan, S J-H; McGeechan, K; Bauman, A; Allman-Farinelli, M

    2015-01-01

    Young adulthood is a high-risk life stage for weight gain. Evidence is needed to translate behavioural approaches into community practice to prevent weight gain in young adults. This systematic review assessed the effectiveness and reporting of external validity components in prevention interventions. The search was limited to randomized controlled trial (RCT) lifestyle interventions for the prevention of weight gain in young adults (18-35 years). Mean body weight and/or body mass index (BMI) change were the primary outcomes. External validity, quality assessment and risk of bias tools were applied to all studies. Twenty-one RCTs were identified through 14 major electronic databases. Over half of the studies were effective in the short term for significantly reducing body weight and/or BMI; however, few showed long-term maintenance. All studies lacked full reporting on external validity components. Description of the intervention components and participant attrition rates were reported by most studies. However, few studies reported the representativeness of participants, effectiveness of recruitment methods, process evaluation detail or costs. It is unclear from the information reported how to implement the interventions into community practice. Integrated reporting of intervention effectiveness and enhanced reporting of external validity components are needed for the translation and potential upscale of prevention strategies. © 2014 World Obesity.

  15. External validity of sentiment mining reports: Can current methods identify demographic biases, event biases, and manipulation of reviews?

    NARCIS (Netherlands)

    Wijnhoven, Alphonsus B.J.M.; Bloemen, Oscar

    2014-01-01

    Many publications in sentiment mining provide new techniques for improved accuracy in extracting features and corresponding sentiments in texts. For the external validity of these sentiment reports, i.e., the applicability of the results to target audiences, it is important to well analyze data of

  16. External Fixation versus two-stage Open Reduction Internal Fixation of distal intra-articular Tibia fractures; a Systematic Review

    DEFF Research Database (Denmark)

    Ladeby Erichsen, Julie; Jensen, Carsten; Damborg, Frank Lindhøj

    Internal Fixation (ORIF) or External Fixation (EF). Method : A search was conducted using PUBMED, Embase, Cochrane Central, Open Grey, Orthopaedic Proceedings and WHO International Clinical Trials Registry Platform. Studies with level of evidence I-IV comparing EF with two-stage ORIF of DIATF in patients...

  17. Impact of Salt Waste Processing Facility Streams on the Nitric-Glycolic Flowsheet in the Chemical Processing Cell

    Energy Technology Data Exchange (ETDEWEB)

    Martino, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-08-08

    An evaluation of the previous Chemical Processing Cell (CPC) testing was performed to determine whether the planned concurrent operation, or “coupled” operations, of the Defense Waste Processing Facility (DWPF) with the Salt Waste Processing Facility (SWPF) has been adequately covered. Tests with the nitricglycolic acid flowsheet, which were both coupled and uncoupled with salt waste streams, included several tests that required extended boiling times. This report provides the evaluation of previous testing and the testing recommendation requested by Savannah River Remediation. The focus of the evaluation was impact on flammability in CPC vessels (i.e., hydrogen generation rate, SWPF solvent components, antifoam degradation products) and processing impacts (i.e., acid window, melter feed target, rheological properties, antifoam requirements, and chemical composition).

  18. From the 'Le Blayais NPP' flooding in 1999 to the review of French regulation for the protection of nuclear facilities against external flooding

    International Nuclear Information System (INIS)

    Dupuy, P.

    2011-01-01

    On 27 December 1999, a severe storm occurred in the vicinity of the 'Le Blayais' Nuclear Power Plant located on the banks of the Gironde estuary. The severe storm-driven waves coincident with high water levels in the Gironde estuary exceeded the worst-case scenario considered at the design of the site protection against flooding, resulting in the scram of three out of four units and severe nuclear island flooding. Several underground rooms sheltering equipment important to safety were flooded. This partial flooding incident has called into question the design bases defined in the French Basic Safety Rule (BSR) I.2.e for the protection of French NPPs against external flooding in particular in terms of flood events and combinations of flood events considered for the design. It has also revealed some weaknesses in the existing measures implemented, especially the site protection dykes, the protection of equipment important to safety, the warning systems and the emergency organization. Following this incident, in addition to the rush through protection measures undertaken on Le Blayais NPP, the utility Electricity De France (EDF) has launched a wide review of the protection of all French NPPs against external flooding. This review is based on a new and more comprehensive methodology for the protection of NPPs against external flooding (called 'REX Blayais methodology'), including a reassessment of flood events and their combinations and of all protection measures. This review has led EDF to carry out a large number of modifications and improvements at all NPP sites. 'REX Blayais methodology' and its application to all French NPPs were submitted to the approval of the French Nuclear Safety Authority (ASN) in 2001 and then in 2007 after being analyzed by its technical support IRSN (French Institute for Radioprotection and Nuclear Safety). The methodology and the level of protection of the NPPs thanks to all the improvements and modifications performed by the utility were

  19. Unresectable Retiform Hemangioendothelioma Treated with External Beam Radiation Therapy and Chemotherapy: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Alina Z. Hirsh

    2010-01-01

    Full Text Available Retiform hemangioendothelioma (RH is an infrequently encountered vascular neoplasm of intermediate or borderline malignancy. Treatment of RH is controversial. We present a case of a 44-year-old Asian male presenting with an unresectable RH of the pelvis. The patient was treated with concurrent low-dose Cisplatin and External beam Radiation (4140cGy in 180cGy per fraction. This is the first report of a clinical complete response and a long-term local control of this rare tumor. This has significant clinical implication, since it gives the first evidence of treatment of this rare tumor using concurrent low-dose chemotherapy and radiation.

  20. Neuraxial analgesia to increase the success rate of external cephalic version: a systematic review and meta-analysis of randomized controlled trials.

    Science.gov (United States)

    Magro-Malosso, Elena Rita; Saccone, Gabriele; Di Tommaso, Mariarosaria; Mele, Michele; Berghella, Vincenzo

    2016-09-01

    External cephalic version is a medical procedure in which the fetus is externally manipulated to assume the cephalic presentation. The use of neuraxial analgesia for facilitating the version has been evaluated in several randomized clinical trials, but its potential effects are still controversial. The objective of the study was to evaluate the effectiveness of neuraxial analgesia as an intervention to increase the success rate of external cephalic version. Searches were performed in electronic databases with the use of a combination of text words related to external cephalic version and neuraxial analgesia from the inception of each database to January 2016. We included all randomized clinical trials of women, with a gestational age ≥36 weeks and breech or transverse fetal presentation, undergoing external cephalic version who were randomized to neuraxial analgesia, including spinal, epidural, or combined spinal-epidural techniques (ie, intervention group) or to a control group (either intravenous analgesia or no treatment). The primary outcome was the successful external cephalic version. The summary measures were reported as relative risk or as mean differences with a 95% confidence interval. Nine randomized clinical trials (934 women) were included in this review. Women who received neuraxial analgesia had a significantly higher incidence of successful external cephalic version (58.4% vs 43.1%; relative risk, 1.44, 95% confidence interval, 1.27-1.64), cephalic presentation in labor (55.1% vs 40.2%; relative risk, 1.37, 95% confidence interval, 1.08-1.73), and vaginal delivery (54.0% vs 44.6%; relative risk, 1.21, 95% confidence interval, 1.04-1.41) compared with those who did not. Women who were randomized to the intervention group also had a significantly lower incidence of cesarean delivery (46.0% vs 55.3%; relative risk, 0.83, 95% confidence interval, 0.71-0.97), maternal discomfort (1.2% vs 9.3%; relative risk, 0.12, 95% confidence interval, 0

  1. External Peer Review Report on the United States Special Operations Command Office of Inspector General Audit Division

    Science.gov (United States)

    2016-08-15

    and procedures to provide it with reasonable assurance of conforming to Government Auditing Standards. The elements of quality control are...organization with reasonable assurance of performing and reporting in conformity with applicable professional standards in all material respects. Audit ...USSOCOM OIG’s audit organization did not perform any nonaudit services during the period of our review so we did not review any nonaudit services

  2. Physical examination of the female internal and external genitalia with and without pelvic organ prolapse: A review.

    Science.gov (United States)

    Pahwa, Avita K; Siegelman, Evan S; Arya, Lily A

    2015-04-01

    Pelvic organ prolapse, a herniation of pelvic organs through the vagina, is a common condition in older women. Pelvic organ prolapse distorts vaginal anatomy making pelvic examination difficult. A clinician must accurately identify anatomic landmarks both in women presenting with symptoms of prolapse and in women noted to have coincidental prolapse during routine gynecologic examination. We present a systematic approach to the female pelvic examination including anatomic landmarks of the external genitalia, vagina, and uterus in women with normal support as well as changes that occur with pelvic organ prolapse. Knowledge and awareness of normal anatomic landmarks will improve a clinician's ability to identify defects in pelvic support and allow for better diagnosis and treatment of pelvic organ prolapse. © 2014 Wiley Periodicals, Inc.

  3. External Beam Radiotherapy for Focal Lymphoepithelioma-Like Carcinoma in the Urinary Bladder: A Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Nobuhiro Kushida

    2015-01-01

    Full Text Available Lymphoepithelioma is a malignant epithelial tumor in the nasopharynx characterized by prominent lymphoid infiltration. Carcinomas that resemble lymphoepitheliomas have been called lymphoepithelioma-like carcinomas and have been reported in other organs. A tumor in the bladder is categorized by the percentage of the total area occupied by the lymphoepithelioma-like carcinoma pattern, with the prognosis dependent on the percentage. We present an 81-year-old man with stage 3 chronic obstructive pulmonary disease and a history of aortic aneurysm repair. The computed tomography scans indicated thickening and irregularity of the bladder wall, with left external iliac lymph node metastasis. His diagnosis was bladder cancer, and the clinical stage was evaluated as T3N1M0. Transurethral resection of the bladder tumor was performed, and the pathological specimen showed that the tumor was composed of undifferentiated malignant cells with sheets and nests arranged in a syncytial pattern, as well as an urothelial carcinoma lesion. A prominent lymphoid reaction accompanied the tumor. The pathological diagnosis was focal-type lymphoepithelioma-like carcinoma containing a component of urothelial carcinoma G3>G2. His general condition was such that he could not tolerate radical cystectomy or systemic chemotherapy. External beam radiotherapy (total 60 Gy was given to the bladder, including the lymph node metastatic lesion. No cancer recurrence was detected by regular follow-up computed tomography and cystoscopy. He eventually died of other causes 48 months later. Although treatment for focal lymphoepithelioma-like carcinoma generally requires multifocal therapies, in the present case, the bladder became tumor free. We also summarize previously reported lymphoepithelioma-like carcinoma cases treated with radiotherapy.

  4. Efficacy and External Validity of Electronic and Mobile Phone-Based Interventions Promoting Vegetable Intake in Young Adults: A Systematic Review Protocol.

    Science.gov (United States)

    Nour, Monica Marina; Chen, Juliana; Allman-Farinelli, Margaret

    2015-07-28

    Despite social marketing campaigns and behavior change interventions, young adults remain among the lowest consumers of vegetables. The digital era offers potential new avenues for both social marketing and individually tailored programs, through texting, web, and mobile applications. The effectiveness and generalizability of such programs have not been well documented. The aim of this systematic review is to evaluate the efficacy and external validity of social marketing, electronic, and mobile phone-based (mHealth) interventions aimed at increasing vegetable intake in young adults. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) protocol will be used to conduct this systematic review. The search strategy will be executed across eleven electronic databases using combinations of the following search terms: "online intervention", "computer-assisted therapy", "internet", "website", "cell phones", "cyber", "telemedicine", "email", "social marketing", "social media", "mass media", "young adult", and "fruit and vegetables". The reference lists of included studies will also be searched for additional citations. Titles and abstracts will be screened against inclusion criteria and full texts of potentially eligible papers will be assessed by two independent reviewers. Data from eligible papers will be extracted. Quality and risk of bias will be assessed using the Effective Public Health Practice Project (EPHPP) Quality Assessment Tool for Quantitative Studies and The Cochrane Collaboration Risk of Bias assessment tool respectively. The external validity of the studies will be determined based on components such as reach, adoption, and representativeness of participants; intervention implementation and adaption; and program maintenance and institutionalization. Results will be reported quantitatively and qualitatively. Our research is in progress. A draft of the systematic review is currently being produced for publication by the end of 2015

  5. Modeling and flowsheet design of an Am separation process using TODGA and H{sub 4}TPAEN

    Energy Technology Data Exchange (ETDEWEB)

    Vanel, V.; Marie, C.; Montuir, M.; Boubals, N.; Sorel, C. [CEA, Centre de Marcoule, Nuclear Energy Division, Radiochemistry and Processes Department, Bagnols-sur-Ceze, F-30207 (France); Kaufholz, P.; Modolo, G. [Forschungszentrum Juelich GmbH, Institute of Energy and Climate Research, Nuclear Waste Management and Reactor Safety, D-52428 (Germany); Geist, A. [Karlsruher Institut fuer Technologie - KIT, Institut fuer Nukleare Entsorgung - INE, Karlsruhe (Germany)

    2016-07-01

    Recycling americium from spent fuels is an important consideration for the future nuclear fuel cycle, as americium is the main contributor to the long-term radiotoxicity and heat power of the final waste, after separation of uranium and plutonium using the PUREX process. The separation of americium alone from a PUREX raffinate can be achieved by co-extracting lanthanide (Ln(III)) and actinide (An(III)) cations into an organic phase containing the diglycolamide extractant TODGA, and then stripping Am(III) with selectivity towards Cm(III) and lanthanides. The water soluble ligand H{sub 4}TPAEN was tested to selectively strip Am from a loaded organic phase. Based on experimental data obtained by Juelich, NNL and CEA laboratories since 2013, a phenomenological model has been developed to simulate the behavior of americium, curium and lanthanides during their extraction by TODGA and their complexation by H{sub 4}TPAEN (complex stoichiometry, extraction and complexation constants, kinetics). The model was gradually implemented in the PAREX code and helped to narrow down the best operating conditions. Thus, the following 2 modifications of initial operating conditions were proposed: -) an increase in the concentration of TPAEN as much as the solubility limit allows, and -) an improvement of the lanthanide scrubbing from the americium flow by adding nitrates to the aqueous phase. A qualification of the model was begun by comparing on the one hand constants determined with the model to those measured experimentally, and on the other hand, simulation results and experimental data on new independent batch experiments. A first sensitivity analysis identified which parameter has the most dominant effect on the process. A flowsheet was proposed for a spiked test in centrifugal contactors performed with a simulated PUREX raffinate with trace amounts of Am and Cm. If the feasibility of the process is confirmed, the results of this test will be used to consolidate the model and to

  6. Spent Nuclear Fuel Reprocessing Flowsheet. A Report by the WPFC Expert Group on Chemical Partitioning of the NEA Nuclear Science Committee

    International Nuclear Information System (INIS)

    Na, Chan; Yamagishi, Isao; Choi, Yong-Joon; Glatz, Jean-Paul; Hyland, Bronwyn; Uhlir, Jan; Baron, Pascal; Warin, Dominique; De Angelis, Giorgio; Luce, Alfredo; INOUE, Tadashi; Morita, Yasuji; Minato, Kazuo; Lee, Han Soo; Ignatiev, Victor V.; Kormilitsyn, Mikhail V.; Caravaca, Concepcion; Lewin, Robert G.; Taylor, Robin J.; Collins, Emory D.; Laidler, James J.

    2012-06-01

    Under the auspices of the NEA Nuclear Science Committee (NSC), the Working Party on Scientific Issues of the Fuel Cycle (WPFC) has been established to co-ordinate scientific activities regarding various existing and advanced nuclear fuel cycles, including advanced reactor systems, associated chemistry and flowsheets, development and performance of fuel and materials, and accelerators and spallation targets. The WPFC has different expert groups to cover a wide range of scientific fields in the nuclear fuel cycle. The Expert Group on Chemical Partitioning was created in 2001 to (1) perform a thorough technical assessment of separations processes in application to a broad set of partitioning and transmutation (P and T) operating scenarios and (2) identify important research, development and demonstration necessary to bring preferred technologies to a deployable stage and (3) recommend collaborative international efforts to further technological development. This report aims to collect spent nuclear fuel reprocessing flowsheet of various processes developed by member states: aqueous, pyro and fluoride volatility. Contents: 1 - Hydrometallurgy process: Standard PUREX, Extended PUREX, UREX+3, Grind/Leach; 2 - Pyrometallurgy process: pyro-process (CRIEPI - Japan), 4-group partitioning process, pyro-process (KAERI - Korea), Direct electrochemical processing of metallic fuel, PyroGreen (reduce radiotoxicity to the level of low and intermediate level waste - LILW); 3 - Fluoride volatility process: Fluoride volatility process, Uranium and protactinium removal from fuel salt compositions by fluorine bubbling, Flowsheet studies on non-aqueous reprocessing of LWR/FBR spent nuclear fuel; Appendix A: Flowsheet studies of RIAR (Russian Federation), List of contributors, Members of the expert group

  7. 77 FR 44613 - Notice of Availability of the External Review Draft of Framework for Human Health Risk Assessment...

    Science.gov (United States)

    2012-07-30

    ...., Washington, DC. The Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is (202) 566-1744, and the telephone... policy, it also emphasizes the importance of scientific review and public involvement. The Framework...

  8. Development of a Relative Potency Factor (Rpf) Approach for Polycyclic Aromatic Hydrocarbon (PAH) Mixtures (External Review Draft)

    Science.gov (United States)

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of polycyclic aromatic hydrocarbon (PAH) mixtures that when finalized will appear on the Integrated Risk Information System (IRIS) database. ...

  9. 77 FR 56202 - Notification of an External Peer Review Meeting for the Draft Framework for Human Health Risk...

    Science.gov (United States)

    2012-09-12

    ... Meeting for the Draft Framework for Human Health Risk Assessment to Inform Decision Making AGENCY: U.S... panel of experts to review the draft document, Framework for Human Health Risk Assessment to Inform... for Human Health Risk Assessment to Inform Decision Making will be held on October 9, 2012, from 9:00...

  10. A Review on the Relationship Between Strategic Management and Performance: The Role of Internal and External Contexts

    Directory of Open Access Journals (Sweden)

    Elif GENÇ

    2015-12-01

    Full Text Available Over the last few decades, strategic management practices have been widely applied in the public sector across the world. Though this approach and its component techniques are still in their infancy, most practitioners and academics have reached a consensus on the role of strategic management in enhancing organisational efficiency. Accordingly, there have been many studies examiningthe relationship between strategic management and performance in public organizations. However, as far as the public sector is concerned, there is still insufficient evidence to indicate that strategic management has a direct link with organizational performance, and it is still unclear whether there are any other determining factors that might affect this alignment. This study aims to investigate the theoretical background to the relationship between strategic management and organizational performance. It also identifies how internal and external contextual factors have mediating and moderating effects on this relationship, and suggests that studies analysing the fit between strategic management practices and performance in public sector organizations should take the influence of contextual parameters into consideration.

  11. Salvage radical prostatectomy after external radiotherapy for prostate cancer: Indications, morbidity and results. Review from CCAFU prostate section

    International Nuclear Information System (INIS)

    Paparel, P.; Soulie, M.; Mongiat-Artus, P.; Cornud, F.; Borgogno, C.; Les membres du sous-comite prostate du CCAFU

    2010-01-01

    Local recurrence after external radiotherapy for prostate cancer occurs in 30 to 50 % and is often diagnosed by a rising PSA. The absence of local control after radiotherapy is a risk factor of metastases and specific mortality. There are several therapeutic options to treat these patients: surveillance, hormonotherapy and salvage therapies (radical prostatectomy, cysto-prostatectomy, brachytherapy, high intensity focused ultrasound [HIFU] and cryotherapy). Hormonotherapy is not a curative treatment and after a couple of years, the disease will progress again. Local salvage therapies are the only treatment to have the potential to cure these patients with the condition of very strict inclusion criteria. Among these therapies, only radical prostatectomy demonstrated his efficacy with a follow-up of 10 years on specific survival and survival without biological progression respectively from 70 to 77 % and from 30 to 43 %. During last decade, morbidity of RP has strongly decreased with a percentage of rectal and ureteral injury at 3 %. Nevertheless, percentage of urinary incontinence remains high from 29 to 50 %. Salvage mini-invasive therapies (cryotherapy, HIFU and cryotherapy) are under constant evolution due to progress of technology. Functional and oncological results are better with last generation devices but need to be evaluated and compared with radical prostatectomy. (authors)

  12. Late Wash/Nitric Acid flowsheet hydrogen generation bases for simulation of a deflagration/detonation in the DWPF CPC

    International Nuclear Information System (INIS)

    Ritter, J.A.

    1993-01-01

    Hydrogen generation data obtained from IDMS runs PX4 and PX5 will be used to determine a bases for a deflagration/detonation simulation in the DWPF CPC. This simulation is necessary due to the new chemistry associated with the Late Wash/ Nitric Acid flowsheet and process modifications associated with the presence of H 2 in the offgas. The simulation will be performed by Professor Van Brunt from the University of South Carolina. The scenario which leads up to the deflagration/detonation simulation will be chosen such that the following conditions apply. The SRAT is filled to its maximum operating level with 9,600 gal of sludge, which corresponds to the minimum vapor space above the sludge. The SRAT is at the boiling point, producing H 2 at a very low rate (about 10 % of the peak) and 15 scfm of air inleakage is entering the SRAT. Then, the H 2 generation rate will be allowed to increase exponentially (catalyst activation) until it readies the peak H 2 generation rate of the IDMS run, after which the H 2 generation rate will be allowed to decay exponentially (catalyst deactivation) until the total amount of H2 produced is between 85 and 100% of that produced during the IDMS run

  13. Sludge Washing And Demonstration Of The DWPF Flowsheet In The SRNL Shielded Cells For Sludge Batch 8 Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Pareizs, J. M.; Crawford, C. L.

    2013-04-26

    The current Waste Solidification Engineering (WSE) practice is to prepare sludge batches in Tank 51 by transferring sludge from other tanks to Tank 51. Tank 51 sludge is washed and transferred to Tank 40, the current Defense Waste Processing Facility (DWPF) feed tank. Prior to transfer of Tank 51 to Tank 40, the Savannah River National Laboratory (SRNL) typically simulates the Tank Farm and DWPF processes using a Tank 51 sample (referred to as the qualification sample). WSE requested the SRNL to perform characterization on a Sludge Batch 8 (SB8) sample and demonstrate the DWPF flowsheet in the SRNL shielded cells for SB8 as the final qualification process required prior to SB8 transfer from Tank 51 to Tank 40. A 3-L sample from Tank 51 (the SB8 qualification sample; Tank Farm sample HTF-51-12-80) was received by SRNL on September 20, 2012. The as-received sample was characterized prior to being washed. The washed material was further characterized and used as the material for the DWPF process simulation including a Sludge Receipt and Adjustment Tank (SRAT) cycle, a Slurry Mix Evaporator (SME) cycle, and glass fabrication and chemical durability measurements.

  14. Determination of fission product and heavy metals inventories in FTE-4 fuel rods by a grind-burn-leach flowsheet

    International Nuclear Information System (INIS)

    Fitzgerald, C.L.; Vaughen, V.C.A.; Lamb, C.E.

    1977-07-01

    Experiments using High-Temperature Gas-Cooled Reactor (HTGR) fuel material, TRISO-coated (2.75 Th/U)C 2 --TRISO-coated ThC 2 and TRISO-coated UO 2 --BISO-coated ThO 2 , were performed in Building 4507 (the High-Level Chemical Development Facility) to determine the inventory and transport behavior of fission products and heavy metals from a grind-burn-leach process flowsheet. In addition, values calculated by the ORNL Isotope Generation and Depletion Code (ORIGEN, a computer program used for predicting quantities of activation products, actinides, and fission products from irradiation data and nuclear data libraries) are compared with values derived by chemical analyses (CA) and those measured by a gamma-scan nondestructive analytical (NDA) technique. Reasonable agreement was obtained between ORIGEN and NDA results for one of the tests, but the values obtained by chemical analysis were lower than either of the two other sets of values. With the exception of 234 U, isotopic uranium values determined by chemical analysis (mass spectrometry) agreed within 15 percent of the ORIGEN prediction

  15. A flowsheet model of a coal-fired MHD/steam combined electricity generating cycle, using the access computer model

    International Nuclear Information System (INIS)

    Davison, J.E.; Eldershaw, C.E.

    1992-01-01

    This document forms the final report on a study of a coal-fired magnetohydrodynamic (MHD)/steam electric power generation system carried out by British Coal Corporation for the Commission of the European Communities. The study objective was to provide mass and energy balances and overall plant efficiency predictions for MHD to assist the Commission in their evaluation of advanced power generation technologies. In early 1990 the British Coal Corporation completed a study for the Commission in which a computer flowsheet modelling package was used to predict the performance of a conceptual air blown MHD plant. Since that study was carried out increasing emphasis has been placed on the possible need to reduce CO 2 emissions to counter the so-called greenhouse effect. Air blown MHD could greatly reduce CO 2 emissions per KWh by virtue of its high thermal efficiency. However, if even greater reductions in CO 2 emissions were required the CO 2 produced by coal combustion may have to be disposed of, for example into the deep ocean or underground caverns. To achieve this at minimum cost a concentrated CO 2 flue gas would be required. This could be achieved in an MHD plant by using a mixture of high purity oxygen and recycled CO 2 flue gas in the combustor. To assess this plant concept the European Commission awarded British Coal a contract to produce performance predictions using the access computer program

  16. Radioactive contamination on land and external radiation dose in residential areas around the former Soviet Union's Semipalatinsk nuclear test site: a review of our studies since 1995

    International Nuclear Information System (INIS)

    Hoshi, M.; Yamamoto, M.; Sakaguchi, A.; Takada, J.; Apsalikov, K.N.; Gusev, B.I.

    2004-01-01

    A review is presented on our studies about radioactive contamination on land and external radiation doses to residents by the thermoluminescence technique, performed around the former Soviet Union's Semipalatinsk nuclear test site (SNTS) in Kazakhstan since 1995. Surface and core soil samples have been collected from different sites around the SNTS and long-lived radionuclides such as 137 Cs and Pu isotopes were measured. Unlike 137 Cs, the inventories of 239,240 Pu for most of the sites we visited were several to a few hundred times higher than those (40-120 Bq/m 2 ) for global fallout observed in Japan. Pu in soil around the SNTS was found to be tightly incorporated into various sizes of particles formed in the course of the condensation of melting materials, such as vaporized soil and bomb components. Lower atomic ratios of 240 Pu/ 239 Pu (0.03-0.05) for samples indicated that the nuclear tests conducted at the SNTS resulted in a relatively large amount of close-in fallout Pu even in the outside regions. External radiation doses to residents near the SNTS were evaluated by the thermoluminescence technique for brick samples collected from several settlements: Dolon, Semipalatinsk and Ust'-Kamenogorsk cities. The external radiation doses to population were estimated to be up to 1.0 Gy for resident in Dolon settlement. The doses in other two cities were evaluated to be several hundreds mGy. The present doses in Ust'-Kamenogorsk City were consistent with the human acute health effect on the citizens just after 1956 fallout. (author)

  17. An external peer review of the U.S. Department of Energy's assessment of ''damages and benefits of the fuel cycles: Estimation methods, impacts, and values''

    International Nuclear Information System (INIS)

    1993-01-01

    The need for better assessments of the ''external'' benefits and costs of environmental effects of various fuel cycles was identified during the development of the National Energy Strategy. The growing importance of this issue was emphasized by US Department of Energy (DOE) management because over half of the states were already pursuing some form of social costing in electricity regulation and a well-established technical basis for such decisions was lacking. This issue was identified as a major area of controversy--both scientifically and politically--in developing energy policies at the state and national level. In 1989, the DOE's Office of Domestic and International Energy Policy commissioned a study of the external environmental damages and benefits of the major fuel cycles involved in electric power generation. Over the next 3-year period, Oak Ridge National Laboratory and Resources for the Future conducted the study and produced a series of documents (fuel cycle documents) evaluating the costs of environmental damages of the coal, oil, natural gas, biomass, hydroelectric, and nuclear fuel cycles, as well as the Background Document on methodological issues. These documents described work that took almost 3 years and $2.5 million to complete and whose implications could be far reaching. In 1992, the Secretary of Energy sought advice on the overall concepts underlying the studies and the means employed to estimate environmental externalities. He asked the Secretary of Energy's Advisory Board to undertake a peer review of the fuel cycle studies and encouraged the Board to turn to outside expertise, as needed

  18. Intrinsic Hormone-Like Molecules and External Root Resorption During Orthodontic Tooth Movement. A Systematic Review and Meta-Analysis in Preclinical in-Vivo Research

    Directory of Open Access Journals (Sweden)

    Andreas Spoerri

    2018-03-01

    Full Text Available Background: External root resorption constitutes an adverse effect of orthodontic treatment. The aim of the present meta-analysis was to identify the effect of induced intrinsic/ hormone-like molecules such as prostaglandins, interleukins and others on external root resorption after orthodontic tooth movement in experimental animalsMethods: An electronic database search of the literature was performed (Medline via PubMed, EMBASE, LILACS, and Open Gray. Search terms included root resorption, tooth movement and animal type. Risk of bias assessment was made using the SYRCLE guidelines for animal studies and reporting quality was assessed through ARRIVE. Random effects meta-analysis was performed for the outcome root resorption after orthodontic tooth movement.Results: Of the 124 articles initially retrieved, 13 were eligible for inclusion in the systematic review, while only 2 were included in the quantitative synthesis. Five studies investigated the effect of Prostaglandin E2, four studies the effect of Thyroxine, two the effect of Calcium ions (Ca++, while the rest investigated Misoprostol, Interleukin-12 and Interleukin-4. Risk of Bias in all studies was judged to be high overall, while reporting quality was suboptimal. According to the quantitative synthesis, there was no difference in root resorption after orthodontic tooth movement when Prostaglandin E2 coupled with Ca++ was administered in comparison to no substance administration (SMD: 0.48 mm2; 95% CI: −0.22, 1.19; p = 0.18.Conclusions: Overall, there was no evidence to suggest a variation in root resorption when Prostaglandin E2 and Ca++ were administered, while there is an overriding need for further high quality experimental studies to inform available evidence on the effect of intrinsic substances on external root resorption.

  19. Intrinsic Hormone-Like Molecules and External Root Resorption During Orthodontic Tooth Movement. A Systematic Review and Meta-Analysis in Preclinical in-Vivo Research.

    Science.gov (United States)

    Spoerri, Andreas; Koletsi, Despina; Eliades, Theodore

    2018-01-01

    Background: External root resorption constitutes an adverse effect of orthodontic treatment. The aim of the present meta-analysis was to identify the effect of induced intrinsic/ hormone-like molecules such as prostaglandins, interleukins and others on external root resorption after orthodontic tooth movement in experimental animals Methods: An electronic database search of the literature was performed (Medline via PubMed, EMBASE, LILACS, and Open Gray). Search terms included root resorption, tooth movement and animal type. Risk of bias assessment was made using the SYRCLE guidelines for animal studies and reporting quality was assessed through ARRIVE. Random effects meta-analysis was performed for the outcome root resorption after orthodontic tooth movement. Results: Of the 124 articles initially retrieved, 13 were eligible for inclusion in the systematic review, while only 2 were included in the quantitative synthesis. Five studies investigated the effect of Prostaglandin E2, four studies the effect of Thyroxine, two the effect of Calcium ions (Ca++), while the rest investigated Misoprostol, Interleukin-12 and Interleukin-4. Risk of Bias in all studies was judged to be high overall, while reporting quality was suboptimal. According to the quantitative synthesis, there was no difference in root resorption after orthodontic tooth movement when Prostaglandin E2 coupled with Ca++ was administered in comparison to no substance administration (SMD: 0.48 mm 2 ; 95% CI: -0.22, 1.19; p = 0.18). Conclusions: Overall, there was no evidence to suggest a variation in root resorption when Prostaglandin E2 and Ca++ were administered, while there is an overriding need for further high quality experimental studies to inform available evidence on the effect of intrinsic substances on external root resorption.

  20. ExternE: Externalities of energy Vol. 1. Summary

    International Nuclear Information System (INIS)

    Holland, M.; Berry, J.

    1995-01-01

    energy use in the transport and domestic sectors and a number of non-environmental externalities. Phase 3 of the project will be undertaken within the European Commission's 4th Framework Programme (1995-1998) and will concentrate on the application of the accounting framework in support of policy issues and decision making. A major result of this work is the methodology which has been developed. This is a significant advance on earlier studies of the external costs of energy. It provides a transparent basis on which different impacts, technologies and locations may be compared. It is suitable for evaluation of the health and environmental damages due to increments in electricity production, with or without monetary valuation of the impacts. This report reviews this methodology and presents the major results obtained in its application to seven important fuel cycles, namely the coal, lignite, oil, gas, nuclear, hydro and wind fuel cycles. Chapter 2 reviews the methodology developed for the quantification of impacts and discusses the associated issues. Chapter 3 discusses the methodological issues associated with the economic valuation of impacts. Chapters 4 and 5 report in detail on the assessment of the coal and nuclear fuel cycles. Chapter 6 summarises the progress that has been made to date on the ExternE Project and presents a comparison of the results obtained for the four fossil fuel cycles together with results from the nuclear and renewable fuel cycles. This project is at the forefront of work in this area. It has drawn together an extensive multidisciplinary team of environmental scientists, energy technologists, health and ecology experts, atmospheric modellers, economists and computer analysts. The results obtained are based on thorough review of scientific and economic studies. This does not mean that exact values have been established for external costs. Indeed, one of our most important conclusions is that the uncertainties are large. Previous analyses

  1. Externalities of fuel cycles 'ExternE' project. Summary report

    International Nuclear Information System (INIS)

    Holland, M.; Berry, J.

    1994-01-01

    energy use in the transport and domestic sectors and a number of non-environmental externalities. Phase 3 of the project will be undertaken within the European Commission's 4th Framework Programme (1995-1998) and will concentrate on the application of the accounting framework in support of policy issues and decision making. A major result of this work is the methodology which has been developed. This is a significant advance on earlier studies of the external costs of energy. It provides a transparent basis on which different impacts, technologies and locations may be compared. It is suitable for evaluation of the health and environmental damages due to increments in electricity production, with or without monetary valuation of the impacts. This report reviews this methodology and presents the major results obtained in its application to seven important fuel cycles, namely the coal, lignite, oil, gas, nuclear, hydro and wind fuel cycles. Chapter 2 reviews the methodology developed for the quantification of impacts and discusses the associated issues. Chapter 3 discusses the methodological issues associated with the economic valuation of impacts. Chapters 4 and 5 report in detail on the assessment of the coal and nuclear fuel cycles. Chapter 6 summarises the progress that has been made to date on the ExternE Project and presents a comparison of the results obtained for the four fossil fuel cycles together with results from the nuclear and renewable fuel cycles. This project is at the forefront of work in this area. It has drawn together an extensive multidisciplinary team of environmental scientists, energy technologists, health and ecology experts, atmospheric modellers, economists and computer analysts. The results obtained are based on thorough review of scientific and economic studies. This does not mean that exact values have been established for external costs. Indeed, one of our most important conclusions is that the uncertainties are large. Previous analyses

  2. External coating of colonic anastomoses

    DEFF Research Database (Denmark)

    Pommergaard, Hans-Christian; Achiam, Michael Patrick; Rosenberg, Jacob

    2012-01-01

    Colon anastomotic leakage remains both a frequent and serious complication in gastrointestinal surgery. External coating of colonic anastomoses has been proposed as a means to lower the rate of this complication. The aim of this review was to evaluate existing studies on external coating of colonic...

  3. Treament of Tibial Plateau Schatzker Type VI Fractures with the Ilizarov Technique Using Ring External Fixators Across the Knee: A Retrospective Review

    Directory of Open Access Journals (Sweden)

    IR Ranatunga

    2010-07-01

    Full Text Available This is a retrospective review of 18 patients with tibial plateau fractures Schatzker type VI. These cases were performed in our medical centre from January 2003 to December 2004. The Ilizarov technique (Russian technique using the ring external fixator was the technique performed. Articular reconstruction and joint alignment were achieved with traction and olive wires with washers. One case required percutaneous elevation of the articular surface and bone grafting through a cortical window. Average clinical union was achieved within 4 months of trauma. Mean final knee flexion was 85°, which is compatible with walking. All patients successfully returned to their previous occupations. In conclusion, the Ilizarov technique has been shown to be a good option and a viable tool in the management of these complex and unstable injuries.

  4. Program Performance Assessment System (PPAS). External reviewers' report of the consultants' meeting on analytical quality control services

    International Nuclear Information System (INIS)

    2001-01-01

    In reviewing the recommendations of previous Consultants' Meetings concerning the AQCS program, it is apparent that there has been a clear and consistent agreement on what the objectives of the AQCS activities should be. The mission statement as given in the Agency's 'Blue Book 1997-1998' states 'To assist analytical laboratories in Member States in maintaining/improving the quality of their analytical measurements, to achieve internationally acceptable levels of quality assurance and to develop and supply appropriate reference standards to achieve these objectives'. In concert with this mission statement, the consultants have endorsed an elaboration of these objectives for both the Agency' s laboratories and Member State laboratories as outlined in the 1994 Consultants' Report (KONA, HI, USA) which includes: the improvement of the reliability of results for the intended purposes; the enhancement of the comparability of results from one measurement laboratory to another; the attainment of compatibility of results in physical and chemical sciences with specific coverage of international standards for food and agriculture, human health, environment, industry, earth sciences, radiation safety, and safeguards activities; the demonstration of quality measurement systems sufficient for laboratory/analyst accreditation or acceptance, and; the establishment of traceability of radioactivity measurements and chemical analyses to the international SI system of measurements

  5. Evaluation of high-level waste vitrification feed preparation chemistry for an NCAW simulant, FY 1994: Alternate flowsheets (DRAFT)

    International Nuclear Information System (INIS)

    Smith, H.D.; Merz, M.D.; Wiemers, K.D.; Smith, G.L.

    1996-02-01

    High-level radioactive waste stored in tanks at the U.S. Department of Energy's (DOE's) Hanford Site will be pretreated to concentrate radioactive constituents and fed to the vitrification plant A flowsheet for feed preparation within the vitrification plant (based on the Hanford Waste Vitrification Plant (HWVP) design) called for HCOOH addition during the feed preparation step to adjust rheology and glass redox conditions. However, the potential for generating H 2 and NH 3 during treatment of high-level waste (HLW) with HCOOH was identified at Pacific Northwest Laboratory (PNL). Studies at the University of Georgia, under contract with Savannah River Technology Center (SRTC) and PNL, have verified the catalytic role of noble metals (Pd, Rh, Ru), present in the waste, in the generation of H 2 and NH 3 . Both laboratory-scale and pilot-scale studies at SRTC have documented the H 2 and NH 3 generation phenomenal Because H 2 and NH 3 may create hazardous conditions in the vessel vapor space and offgas system of a vitrification plant, reducing the H 2 generation rate and the NH 3 generation to the lowest possible levels consistent with desired melter feed characteristics is important. The Fiscal Year 1993 and 1994 studies were conducted with simulated (non-radioactive), pre-treated neutralized current acid waste (NCAW). Neutralized current acid waste is a high-level waste originating from the plutonium/uranium extraction (PUREX) plant that has been partially denitrated with sugar, neutralized with NaOH, and is presently stored in double-shell tanks. The non-radioactive simulant used for the present study includes all of the trace components found in the waste, or substitutes a chemically similar element for radioactive or very toxic species. The composition and simulant preparation steps were chosen to best simulate the chemical processing characteristics of the actual waste

  6. Case study on chemical plant accidents for flow-sheet design of the HTTR-IS system

    International Nuclear Information System (INIS)

    Homma, Hiroyuki; Sato, Hiroyuki; Kasahara, Seiji; Hara, Teruo; Kato, Ryoma; Sakaba, Nariaki; Ohashi, Hirofumi

    2007-02-01

    At the present time, we are alarmed by depletion of fossil energy and adverse effect of rapid increase in fossil fuel burning on environment such as climate changes and acid rain, because our lives depend still heavily upon fossil energy. It is thus widely recognized that hydrogen is one of important future energy carriers in which it is used without emission of carbon dioxide greenhouse gas and atmospheric pollutants and that hydrogen demand will increase greatly as fuel cells are developed and applied widely in the near future. To meet massive demand of hydrogen, hydrogen production from water utilizing nuclear, especially by thermochemical water-splitting Iodine-Sulphur (IS) process utilizing heat from High-Temperature Gas-cooled Reactors (HTGRs), offers one of the most attractive zero-emission energy strategies and the only one practical on a substantial scale. However, to establish a technology based for the HTGR hydrogen production by the IS process, we should close several technology gaps through R and D with the High-Temperature Engineering Test Reactor (HTTR), which is the only Japanese HTGR built and operated at the Oarai Research and Development Centre of Japan Atomic Energy Agency (JAEA). We have launched design studies of the IS process hydrogen production system coupled with the HTTR (HTTR-IS system) to demonstrate HTGR hydrogen production. In designing the HTTR-IS system, it is necessary to consider preventive and breakdown maintenance against accidents occurred in the IS process as a chemical plant. This report describes case study on chemical plant accidents relating to the IS process plant and shows a proposal of accident protection measures based on above case study, which is necessary for flow-sheet design of the HTTR-IS system. (author)

  7. Radiologically determined orthodontically induced external apical root resorption in incisors after non-surgical orthodontic treatment of class II division 1 malocclusion: a systematic review.

    Science.gov (United States)

    Tieu, Long D; Saltaji, Humam; Normando, David; Flores-Mir, Carlos

    2014-07-23

    This study aims to critically evaluate orthodontically induced external apical root resorption (OIEARR) in incisors of patients undergoing non-surgical orthodontic treatment of class II division 1 malocclusion by a systematic review of the published data. An electronic search of two databases was performed; the bibliographies of relevant articles were also reviewed. Studies were included if they examined the amount of OIEARR in incisors produced during non-surgical orthodontic treatment of individuals with class II division I malocclusion in the permanent dentition. Individuals had no previous history of OIEARR, syndromes, pathologies, or general diseases. Study selections, risk of bias assessment, and data extraction were performed in duplicate. Eight studies of moderate methodological quality were finally included. An increased prevalence (65.6% to 98.1%) and mild to moderate severity of OIEARR (root) were reported. No sex difference in root resorption was found. For the maxillary incisors, there was no evidence that either the central or lateral incisor was more susceptible to OIEARR. A weak to moderate positive correlation between treatment duration and root resorption, and anteroposterior apical displacement and root resorption was found. Current limited evidence suggests that non-surgical comprehensive orthodontic treatment to correct class II division 1 malocclusions causes increased prevalence and severity of OIEARR the more the incisor roots are displaced and the longer this movement takes.

  8. A story of scrutiny and fear: Australian midwives' experiences of an external review of obstetric services, being involved with litigation and the impact on clinical practice.

    Science.gov (United States)

    Hood, Laraine; Fenwick, Jennifer; Butt, Janice

    2010-06-01

    to describe Australian midwives' experiences of an external review of obstetric services, involvement in legal proceedings and the impact on midwives' clinical practice and personal wellbeing. the external review process (commonly referred to as the 'Douglas Inquiry') was initiated by a state government and was in response to hospital staff and consumer complaints that focused on anomalies in client care and a significantly high rate of adverse outcomes and clinical errors. It took place within the context of a number of legal proceedings against medical practitioners. As a result, some midwives employed by the hospital were called to give evidence at a variety of legal forums. a qualitative study using an explorative descriptive design. Snowball sampling was used to invite 16 Australian midwives to participate in a tape-recorded interview. Thematic analysis and the techniques associated with constant comparison were used to analyse the data. Australian maternity tertiary referral centre. the analysis identified two overarching themes, 'A story of scrutiny' and 'A story of fear', each with a number of subthemes. 'A story of scrutiny' consists of three subthemes. 'A cloak and dagger affair' reflects the midwives' sense of being and feeling 'exposed' and 'vulnerable' whilst simultaneously being 'kept in the dark' and uninformed during the review process. The subtheme 'Being thrown to the wolves' describes the midwives' experiences of being involved, as witnesses, in medico-legal proceedings. The third subtheme, 'The Inquiry followed them home' outlines the effect on midwives' emotional wellbeing and personal relationships. The second major theme, 'A story of fear' again consists of a number of subthemes. 'Feeling unsafe at work: a culture of fear' describes the midwives' experiences of working within an environment they perceive as driven by the fear of litigation. In order to protect themselves and maintain a sense of control, the midwives adopted a number of

  9. Chest Reirradiation With External Beam Radiotherapy for Locally Recurrent Non-Small-Cell Lung Cancer: A Review

    International Nuclear Information System (INIS)

    Jeremic, Branislav; Videtic, Gregory M.M.

    2011-01-01

    appropriately characterize the historic practice relevant to thoracic reirradiation of recurrent lung cancer, we carried out a comprehensive search of the English-language literature to identify and review relevant studies of the use of EBRT in the treatment of locally recurrent cancer. We limited our scope to treatment of NSCLC and excluded other RT modalities such as brachytherapy and stereotactic body radiotherapy (SBRT). The goal of this systematic review was to better inform current practice in order to ultimately generate appropriate future research endeavors in this setting.

  10. Internal versus external fixation of the anterior component in unstable fractures of the pelvic ring: pooled results from a systematic review.

    Science.gov (United States)

    Wardle, B; Eslick, G D; Sunner, P

    2016-10-01

    Improving reduction of the pelvic ring improves long-term functional outcomes for patients. It has been demonstrated that posterior internal fixation is necessary to adequately control fractures to the posterior ring and there is evidence that supplementing this with fixation of the anterior ring improves stability. It is accepted that internal fixation provides greater stability than external fixation of the anterior ring but long-term differences in radiographic and functional outcomes have not yet been quantified. A search of electronic databases, reference lists and review articles from 1989 to 2015 yielded 18 studies (n = 884) that met our inclusion criteria. We included studies that discussed pelvic ring injuries in adults, reported functional or radiological outcomes or complications by anterior ring intervention and exceeded 14 patients. We excluded biomechanical and cadaver studies. Internal fixation of the anterior pelvic ring had better functional and radiographic outcomes. Residual displacement of >10 mm was less common with internal fixation (ER 0.12, 95 % CI 0.06-0.24) than external fixation (ER 0.31, 95 % CI 0.11-0.62). Unsatisfactory outcomes also occurred at a lower rate (ER 0.09, 95 % CI 0.03-0.22) compared to external fixation (ER 0.32, 95 % CI 0.18-0.50). Losses of reduction (ER 0.02, 95 % CI 0.01-0.04 versus ER 0.07, 95 % CI 0.02-0.21), malunions (ER 0.03, 95 % CI 0.01-0.08 versus ER 0.07, 95 % CI 0.02-0.21) and delayed/non-unions (ER 0.02, 95 % CI 0.01-0.05 versus ER 0.04, 95 % CI 0.02-0.07). Internal fixation of the anterior pelvic ring as supplementary fixation for unstable injuries to the pelvic ring appears to result in better radiographic and functional outcomes as well as fewer complications. However, data that separated outcomes and complications in relation to interventions of the anterior pelvic ring were limited. More studies looking specifically at outcomes in relation to the type of anterior ring intervention are

  11. Efficacy and External Validity of Electronic and Mobile Phone-Based Interventions Promoting Vegetable Intake in Young Adults: Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Nour, Monica; Chen, Juliana; Allman-Farinelli, Margaret

    2016-04-08

    Young adults (18-35 years) remain among the lowest vegetable consumers in many western countries. The digital era offers opportunities to engage this age group in interventions in new and appealing ways. This systematic review evaluated the efficacy and external validity of electronic (eHealth) and mobile phone (mHealth) -based interventions that promote vegetable intake in young adults. We searched several electronic databases for studies published between 1990 and 2015, and 2 independent authors reviewed the quality and risk of bias of the eligible papers and extracted data for analyses. The primary outcome of interest was the change in vegetable intake postintervention. Where possible, we calculated effect sizes (Cohen d and 95% CIs) for comparison. A random effects model was applied to the data for meta-analysis. Reach and representativeness of participants, intervention implementation, and program maintenance were assessed to establish external validity. Published validation studies were consulted to determine the validity of tools used to measure intake. We applied the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to evaluate the overall quality of the body of evidence. Of the 14 studies that met the selection criteria, we included 12 in the meta-analysis. In the meta-analysis, 7 studies found positive effects postintervention for fruit and vegetable intake, Cohen d 0.14-0.56 (pooled effect size 0.22, 95% CI 0.11-0.33, I(2)=68.5%, P=.002), and 4 recorded positive effects on vegetable intake alone, Cohen d 0.11-0.40 (pooled effect size 0.15, 95% CI 0.04-0.28, I(2)=31.4%, P=.2). These findings should be interpreted with caution due to variability in intervention design and outcome measures. With the majority of outcomes documented as a change in combined fruit and vegetable intake, it was difficult to determine intervention effects on vegetable consumption specifically. Measurement of intake was most commonly by self

  12. Material compatibility evaluation for DWPF nitric-glycolic acid-literature review

    Energy Technology Data Exchange (ETDEWEB)

    Mickalonis, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Skidmore, E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2013-06-01

    Glycolic acid is being evaluated as an alternative for formic and nitric acid in the DWPF flowsheet. Demonstration testing and modeling for this new flowsheet has shown that glycolic acid and glycolate has a potential to remain in certain streams generated during the production of the nuclear waste glass. A literature review was conducted to assess the impact of glycolic acid on the corrosion of the materials of construction for the DWPF facility as well as facilities downstream which may have residual glycolic acid and glycolates present. The literature data was limited to solutions containing principally glycolic acid.

  13. Checklists for external validity

    DEFF Research Database (Denmark)

    Dyrvig, Anne-Kirstine; Kidholm, Kristian; Gerke, Oke

    2014-01-01

    to an implementation setting. In this paper, currently available checklists on external validity are identified, assessed and used as a basis for proposing a new improved instrument. METHOD: A systematic literature review was carried out in Pubmed, Embase and Cinahl on English-language papers without time restrictions....... The retrieved checklist items were assessed for (i) the methodology used in primary literature, justifying inclusion of each item; and (ii) the number of times each item appeared in checklists. RESULTS: Fifteen papers were identified, presenting a total of 21 checklists for external validity, yielding a total...... of 38 checklist items. Empirical support was considered the most valid methodology for item inclusion. Assessment of methodological justification showed that none of the items were supported empirically. Other kinds of literature justified the inclusion of 22 of the items, and 17 items were included...

  14. Independent Calculations for the SR Can Assessment. External review contribution in support of SKI's and SSI's review of SR-Can

    Energy Technology Data Exchange (ETDEWEB)

    Maul, Philip; Robinson, Peter; Bond, Alex; Benbow, Steven (Quintessa Limited, Henley-on-Thames (GB))

    2008-03-15

    SKB has published the SR-Can assessment of a deep repository for spent fuel at either the Forsmark or Laxemar sites. This is the final assessment prior to a formal regulatory submission. A number of independent calculations have been undertaken in support of SKI's review of SR-Can. The types of calculations are: 1. direct checks of specified SKB calculations; 2. reproduction of SKB computer calculations with independent codes, to ensure that what SKB has done is properly understood, and to check that the calculations are properly documented; and 3. independent calculations to investigate particular aspects of the safety case. The data used by SKB in its Performance Assessment calculations have not been subject to detailed review. The independent calculations provide information on: 1. where independent calculations have been able to provide support for the arguments put forward by SKB; 2. areas where insufficient information has been provided by SKB to enable a third party to reproduce the SR-Can calculations; and 3. areas where calculations lead to questions about the validity of SKB's arguments. The timescale for the production of the present report has been determined by the timescales for SKI's review of the SR-Can assessment. As a result, some of the independent calculations referred to have not been fully documented, and this will be carried out in 2008. The following conclusions have been drawn. 1. SKB has worked hard to respond to criticisms of previous performance assessments, and SR-Can is an impressive piece of work. 2. In several areas either insufficient or inconsistent information has been presented so that a full reproduction of SKB's calculations has not been possible. This is an important area where SKB will need to improve the presentation of its assessment for SR-Site. 3. There are several areas where SKB's description of post-closure repository evolution needs to be further reviewed. Overall SKB have given only limited

  15. Assessment of generalizability, applicability and predictability (GAP) for evaluating external validity in studies of universal family-based prevention of alcohol misuse in young people: systematic methodological review of randomized controlled trials.

    Science.gov (United States)

    Fernandez-Hermida, Jose Ramon; Calafat, Amador; Becoña, Elisardo; Tsertsvadze, Alexander; Foxcroft, David R

    2012-09-01

    To assess external validity characteristics of studies from two Cochrane Systematic Reviews of the effectiveness of universal family-based prevention of alcohol misuse in young people. Two reviewers used an a priori developed external validity rating form and independently assessed three external validity dimensions of generalizability, applicability and predictability (GAP) in randomized controlled trials. The majority (69%) of the included 29 studies were rated 'unclear' on the reporting of sufficient information for judging generalizability from sample to study population. Ten studies (35%) were rated 'unclear' on the reporting of sufficient information for judging applicability to other populations and settings. No study provided an assessment of the validity of the trial end-point measures for subsequent mortality, morbidity, quality of life or other economic or social outcomes. Similarly, no study reported on the validity of surrogate measures using established criteria for assessing surrogate end-points. Studies evaluating the benefits of family-based prevention of alcohol misuse in young people are generally inadequate at reporting information relevant to generalizability of the findings or implications for health or social outcomes. Researchers, study authors, peer reviewers, journal editors and scientific societies should take steps to improve the reporting of information relevant to external validity in prevention trials. © 2012 The Authors. Addiction © 2012 Society for the Study of Addiction.

  16. External hydrocephalus (benign extra-axial collections of infancy) - review of 15 cases; Hidrocefalia externa colecao extra-axial benigna da infancia - revisao de 15 casos

    Energy Technology Data Exchange (ETDEWEB)

    Machado Junior, Marcos Alberto da Costa; Matos, Paulo Engracio de; Barbosa, Veronica Aline [Fundacao Monte Tabor, Salvador, BA (Brazil). Hospital Sao Rafael. Servico de Bioimagem; Vieira, Naiara Argollo [Hospital Salvador, BA (Brazil); Vieira, Lauro Conceicao Nascimento [Fundacao Monte Tabor, Salvador, BA (Brazil). Hospital Sao Rafael. Servico de Ressonancia Magnetica; Puglio, Nadja; Bacelar, Aroldo [Fundacao Monte Tabor, Salvador, BA (Brazil). Hospital Sao Rafael

    1997-03-01

    The authors studied 15 cases of external hydrocephalus over a 7-year period (September 1987 to May 1995). External hydrocephalus is a condition in which infants with rapidly enlarging heads are found to have a MRI showing widening of subarachnoid space with mild or no ventricular dilatation. Some of the MRI were compared with those of patients with cerebral atrophy and some etiopathogenic hypothesis are presented. These findings indicate that external hydrocephalus is an age-related self-limited condition occurring in infants with open cranial sutures and that it usually resolves without intervention after the second or third year of age. (author) 21 refs., 4 figs.

  17. DWPF Flowsheet Studies with Simulants to Determine Modular Caustic Side Solvent Extraction Unit Solvent Partitioning and Verify Actinide Removal Process Incorporation Strategy

    International Nuclear Information System (INIS)

    Herman, C

    2006-01-01

    The Actinide Removal Process (ARP) facility and the Modular Caustic Side Solvent Extraction Unit (MCU) are scheduled to begin processing salt waste in fiscal year 2007. A portion of the streams generated in the salt processing facilities will be transferred to the Defense Waste Processing Facility (DWPF) to be incorporated in the glass matrix. Before the streams are introduced, a combination of impact analyses and research and development studies must be performed to quantify the impacts on DWPF processing. The Process Science and Engineering (PS and E) section of the Savannah River National Laboratory (SRNL) was requested via Technical Task Request (TTR) HLW/DWPF/TTR-2004-0031 to evaluate the impacts on DWPF processing. Simulant Chemical Process Cell (CPC) flowsheet studies have been performed using previous composition and projected volume estimates for the ARP sludge/monosodium titanate (MST) stream. Due to changes in the flammability control strategy for DWPF for salt processing, the incorporation strategy for ARP has changed and additional ARP flowsheet tests were necessary to validate the new processing strategy. The last round of ARP testing included the incorporation of the MCU stream and identified potential processing issues with the MCU solvent. The identified issues included the potential carry-over and accumulation of the MCU solvent components in the CPC condensers and in the recycle stream to the Tank Farm. Therefore, DWPF requested SRNL to perform additional MCU flowsheet studies to better quantify the organic distribution in the CPC vessels. The previous MCU testing used a Sludge Batch 4 (SB4) simulant since it was anticipated that both of these facilities would begin salt processing during SB4 processing. The same sludge simulant recipe was used in this round of ARP and MCU testing to minimize the number of changes between the two phases of testing so a better comparison could be made. ARP and MCU stream simulants were made for this phase of

  18. Development and testing of a SREX flowsheet for the partitioning of strontium and lead from simulated ICPP sodium-bearing waste

    International Nuclear Information System (INIS)

    Law, J.D.; Wood, D.J.

    1996-11-01

    Laboratory experimentation has indicated that the SREX process is effective for partitioning 90 Sr from acidic radioactive waste solutions located at the Idaho Chemical Processing Plant. Previous countercurrent flowsheet testing of the SREX process with simulated waste resulted in 99.98% removal of Sr. With this previous test, however, Pb was extracted by the SREX solvent and was not back-extracted in the dilute nitric acid strip section. The Pb concentration increased in the recycled solvent and in the aqueous phase of the strip section, resulting in the formation of a Pb precipitate. Subsequently, studies were initiated to identify alternative stripping agents which will selectively strip Sr and Pb from the SREX solvent. Based on the results of these studies, a countercurrent flow sheet was developed and tested in the 5.5-cm Centrifugal Contactor Mockup using simulated waste. The flowsheet tested consisted of an extraction section (0.15 M 4',4'(5)-di-(tert-butyldicyclohexo)-18-crown-6 and 1.2 M TBP in Isopar-L reg-sign), a 0.05 M nitric acid strip section for the removal of Sr from the SREX solvent, a 0.1 M ammonium citrate strip section for the removal of Pb from the SREX solvent, and a 2.0 M nitric acid equilibration section. The behavior of Sr, Pb, Al, Ca, Hg, Na, Zr, and H + was evaluated. The described flowsheet successfully extracted and selectively stripped Sr and Pb from the SBW simulant. Removal efficiencies of 97.9% and 99.91% were obtained for Sr and Pb, respectively. Essentially all of the extracted Sr (99.998%) and 1.9% of extracted Pb exited with the 0.05 M nitric acid strip product; whereas, 0.002% of the extracted Sr and 97.9% of the extracted Pb existed with the 0.1 M ammonium citrate strip product. Also, 95% of the Hg and 63% of the Zr were extracted by the SREX solvent

  19. Uranium extraction from ores with lemon juice I,b-uranium recovery from pregnant lemon juice liquors obtained by attacking phosphate ores and suggested flowsheet

    International Nuclear Information System (INIS)

    EL-Sayed, M.H.

    1992-01-01

    In order to recover uranium from the pregnant liquors obtained by attacking safaga phosphate and qatrani phosphatic sandstone ore materials with lemon juice, methylation for acidic fraction-salt separation has been carried out. Afterwards, separation of uranium from the associated calcium (mainly present in lemon juice liquors as citrate) has been performed by making-use of the wide difference in their water solubility. The solutions containing the separated uranium were then subjected to evaporation till dryness whereby the precipitated uranyl citrate was calcined at 500 degree C to obtain the yellow orange oxide powder (U o 3 ). On the basis of one ton ore treatment, a flowsheet for uranium recovery from the two ore materials has been suggested

  20. Uranium extraction from ores with lemon juice; II,b. uranium recovery from pregnant lemon juice liquors obtained by attacking phosphate ore and suggested flowsheet

    International Nuclear Information System (INIS)

    Hussein, E.M.

    1997-01-01

    In order to recover uranium from the pregnant liquors obtained by attacking Safaga phosphate and Qatrani phosphatic sandstone ore materials with lemon juice, methylation for acidic fraction-salt separation has been carried out. Afterwards, separation of uranium from the associated calcium (mainly present in lemon juice liquors as citrate) has been performed by making-use of the wide difference in their water solubility. The solutions containing the separated uranium were then subjected to evaporation till dryness whereby the precipitated uranyl citrate was calcined at 500 degree C to obtain the yellow orange oxide powder (UO 3 ). On the basis of one ton ore treatment, a flowsheet for uranium recovery from the two ore materials has been suggested

  1. The conceptual flowsheet of effluent treatment during total gelation of uranium process for preparing ceramic UO2 particles of high temperature gas-cooled reactors

    International Nuclear Information System (INIS)

    Quan Ying; Chen Xiaotong; Wang Yang; Liu Bing; Tang Yaping; Tang Chunhe

    2014-01-01

    Today, more and more people pay attention to the environmental protection and ecological environment. Along with the development of nuclear industry, many radioactive effluents may be discharged into environment, which can lead to the pollutions of water, atmosphere and soil. So radioactive effluents including low-activity and medium-level wastes solution treatments have been becoming one of significant subjects. High temperature gas-cooled reactor (HTR) is one of advanced nuclear reactors owing to its reliability, security and broad application in which the fabrication of spherical fuel element is a key technology. During the production of spherical fuel elements, the radioactive effluent treatment is necessary. Referring to the current treatment technologies and methods, the conceptual flowsheet of low-level radioactive effluent treatment during preparing spherical fuel elements was summarized which met the 'Zero Emission' demand. (authors)

  2. Antifoam Degradation Products in Off Gas and Condensate of Sludge Batch 9 Simulant Nitric-Formic Flowsheet Testing for the Defense Waste Processing Facility

    Energy Technology Data Exchange (ETDEWEB)

    Smith, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-04-14

    Ten chemical processing cell (CPC) experiments were performed using simulant to evaluate Sludge Batch 9 for sludge-only and coupled processing using the nitric-formic flowsheet in the Defense Waste Processing Facility (DWPF). Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) cycles were performed on eight of the ten. The other two were SRAT cycles only. Samples of the condensate, sludge, and off gas were taken to monitor the chemistry of the CPC experiments. The Savannah River National Laboratory (SRNL) has previously shown antifoam decomposes to form flammable organic products, (hexamethyldisiloxane (HMDSO), trimethylsilanol (TMS), and propanal), that are present in the vapor phase and condensate of the CPC vessels. To minimize antifoam degradation product formation, a new antifoam addition strategy was implemented at SRNL and DWPF to add antifoam undiluted.

  3. Review of thorium fuel reprocessing experience

    International Nuclear Information System (INIS)

    Brooksbank, R.E.; McDuffee, W.T.; Rainey, R.H.

    1978-01-01

    The review reveals that experience in the reprocessing of irradiated thorium materials is limited. Plants that have processed thorium-based fuels were not optimized for the operations. Previous demonstrations of several viable flowsheets provide a sound technological base for the development of optimum reprocessing methods and facilities. In addition to the resource benefit by using thorium, recent nonproliferation thrusts have rejuvenated an interest in thorium reprocessing. Extensive radiation is generated as the result of 232 U-contamination produced in the 233 U, resulting in the remote operation and fabrication operations and increased fuel cycle costs. Development of the denatured thorium flowsheet, which is currently of interest because of nonproliferation concerns, represents a difficult technological challenge

  4. Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review, and meta-analysis.

    Science.gov (United States)

    Blake, P; Swart, Ann Marie; Orton, J; Kitchener, H; Whelan, T; Lukka, H; Eisenhauer, E; Bacon, M; Tu, D; Parmar, M K B; Amos, C; Murray, C; Qian, W

    2009-01-10

    Early endometrial cancer with low-risk pathological features can be successfully treated by surgery alone. External beam radiotherapy added to surgery has been investigated in several small trials, which have mainly included women at intermediate risk of recurrence. In these trials, postoperative radiotherapy has been shown to reduce the risk of isolated local recurrence but there is no evidence that it improves recurrence-free or overall survival. We report the findings from the ASTEC and EN.5 trials, which investigated adjuvant external beam radiotherapy in women with early-stage disease and pathological features suggestive of intermediate or high risk of recurrence and death from endometrial cancer. Between July, 1996, and March, 2005, 905 (789 ASTEC, 116 EN.5) women with intermediate-risk or high-risk early-stage disease from 112 centres in seven countries (UK, Canada, Poland, Norway, New Zealand, Australia, USA) were randomly assigned after surgery to observation (453) or to external beam radiotherapy (452). A target dose of 40-46 Gy in 20-25 daily fractions to the pelvis, treating five times a week, was specified. Primary outcome measure was overall survival, and all analyses were by intention to treat. These trials were registered ISRCTN 16571884 (ASTEC) and NCT 00002807 (EN.5). After a median follow-up of 58 months, 135 women (68 observation, 67 external beam radiotherapy) had died. There was no evidence that overall survival with external beam radiotherapy was better than observation, hazard ratio 1.05 (95% CI 0.75-1.48; p=0.77). 5-year overall survival was 84% in both groups. Combining data from ASTEC and EN.5 in a meta-analysis of trials confirmed that there was no benefit in terms of overall survival (hazard ratio 1.04; 95% CI 0.84-1.29) and can reliably exclude an absolute benefit of external beam radiotherapy at 5 years of more than 3%. With brachytherapy used in 53% of women in ASTEC/EN.5, the local recurrence rate in the observation group at 5 years

  5. External Measures of Cognition

    Directory of Open Access Journals (Sweden)

    Osvaldo eCairo

    2011-10-01

    Full Text Available The human brain is undoubtedly the most impressive, complex and intricate organ that has evolved over time. It is also probably the least understood, and for that reason, the one that is currently attracting the most attention. In fact, the number of comparative analyses that focus on the evolution of brain size in Homo sapiens and other species has increased dramatically in recent years. In neuroscience, no other issue has generated so much interest and been the topic of so many heated debates as the difference in brain size between socially defined population groups, both its connotations and implications. For over a century, external measures of cognition have been related to intelligence. However, it is still unclear whether these measures actually correspond to cognitive abilities. In summary, this paper must be reviewed with this premise in mind.

  6. A Rare Case Report and Literature Review of External Auditory Canal Cholesteatoma with Circumferential Destruction of Canal Wall Exposing Facial Nerve

    Directory of Open Access Journals (Sweden)

    Leison Maharjan

    2017-01-01

    Full Text Available External auditory canal cholesteatoma (EACC is a rare condition with an estimated incidence of 1.2 per 1000 new otological patients. It is often mistaken with keratosis obturans. We discuss an extensive primary EACC with an aural polyp in a male which was managed by modified radical mastoidectomy.

  7. Regulating multiple externalities

    DEFF Research Database (Denmark)

    Waldo, Staffan; Jensen, Frank; Nielsen, Max

    2016-01-01

    Open access is a well-known externality problem in fisheries causing excess capacity and overfishing. Due to global warming, externality problems from CO2 emissions have gained increased interest. With two externality problems, a first-best optimum can be achieved by using two regulatory instrume......Open access is a well-known externality problem in fisheries causing excess capacity and overfishing. Due to global warming, externality problems from CO2 emissions have gained increased interest. With two externality problems, a first-best optimum can be achieved by using two regulatory...

  8. ExternE National Implementation Finland

    Energy Technology Data Exchange (ETDEWEB)

    Pingoud, K; Maelkki, H; Wihersaari, M; Pirilae, P [VTT Energy, Espoo (Finland); Hongisto, M [Imatran Voima Oy, Vantaa (Finland); Siitonen, S [Ekono Energy Ltd, Espoo (Finland); Johansson, M [Finnish Environment Institute, Helsinki (Finland)

    1999-07-01

    ExternE National Implementation is a continuation of the ExternE Project, funded in part by the European Commission's Joule III Programme. This study is the result of the ExternE National Implementation Project for Finland. Three fuel cycles were selected for the Finnish study: coal, peat and wood-derived biomass, which together are responsible for about 40% of total electricity generation in Finland and about 75% of the non-nuclear fuel based generation. The estimated external costs or damages were dominated by the global warming (GW) impacts in the coal and peat fuel cycles, but knowledge of the true GW impacts is still uncertain. From among other impacts that were valued in monetary terms the human health damages due to airborne emissions dominated in all the three fuel cycles. Monetary valuation for ecosystem impacts is not possible using the ExternE methodology at present. The Meri-Pori power station representing the coal fuel cycle is one of the world's cleanest and most efficient coal-fired power plants with a condensing turbine. The coal is imported mainly from Poland. The estimated health damages were about 4 mECU/kWh, crop damages an order of magnitude lower and damages caused to building materials two orders of magnitude lower. The power stations of the peat and biomass fuel cycles are of CHP type, generating electricity and heat for the district heating systems of two cities. Their fuels are of domestic origin. The estimated health damages allocated to electricity generation were about 5 and 6 mECU/kWh, respectively. The estimates were case-specific and thus an generalisation of the results to the whole electricity generation in Finland is unrealistic. Despite the uncertainties and limitations of the methodology, it is a promising tool in the comparison of similar kinds of fuel cycles, new power plants and pollution abatement technologies and different plant locations with each other. (orig.)

  9. ExternE National Implementation Finland

    International Nuclear Information System (INIS)

    Pingoud, K.; Maelkki, H.; Wihersaari, M.; Pirilae, P.; Hongisto, M.; Siitonen, S.; Johansson, M.

    1999-01-01

    ExternE National Implementation is a continuation of the ExternE Project, funded in part by the European Commission's Joule III Programme. This study is the result of the ExternE National Implementation Project for Finland. Three fuel cycles were selected for the Finnish study: coal, peat and wood-derived biomass, which together are responsible for about 40% of total electricity generation in Finland and about 75% of the non-nuclear fuel based generation. The estimated external costs or damages were dominated by the global warming (GW) impacts in the coal and peat fuel cycles, but knowledge of the true GW impacts is still uncertain. From among other impacts that were valued in monetary terms the human health damages due to airborne emissions dominated in all the three fuel cycles. Monetary valuation for ecosystem impacts is not possible using the ExternE methodology at present. The Meri-Pori power station representing the coal fuel cycle is one of the world's cleanest and most efficient coal-fired power plants with a condensing turbine. The coal is imported mainly from Poland. The estimated health damages were about 4 mECU/kWh, crop damages an order of magnitude lower and damages caused to building materials two orders of magnitude lower. The power stations of the peat and biomass fuel cycles are of CHP type, generating electricity and heat for the district heating systems of two cities. Their fuels are of domestic origin. The estimated health damages allocated to electricity generation were about 5 and 6 mECU/kWh, respectively. The estimates were case-specific and thus an generalisation of the results to the whole electricity generation in Finland is unrealistic. Despite the uncertainties and limitations of the methodology, it is a promising tool in the comparison of similar kinds of fuel cycles, new power plants and pollution abatement technologies and different plant locations with each other. (orig.)

  10. ExternE National Implementation Finland

    Energy Technology Data Exchange (ETDEWEB)

    Pingoud, K.; Maelkki, H.; Wihersaari, M.; Pirilae, P. [VTT Energy, Espoo (Finland); Hongisto, M. [Imatran Voima Oy, Vantaa (Finland); Siitonen, S. [Ekono Energy Ltd, Espoo (Finland); Johansson, M. [Finnish Environment Institute, Helsinki (Finland)

    1999-07-01

    ExternE National Implementation is a continuation of the ExternE Project, funded in part by the European Commission's Joule III Programme. This study is the result of the ExternE National Implementation Project for Finland. Three fuel cycles were selected for the Finnish study: coal, peat and wood-derived biomass, which together are responsible for about 40% of total electricity generation in Finland and about 75% of the non-nuclear fuel based generation. The estimated external costs or damages were dominated by the global warming (GW) impacts in the coal and peat fuel cycles, but knowledge of the true GW impacts is still uncertain. From among other impacts that were valued in monetary terms the human health damages due to airborne emissions dominated in all the three fuel cycles. Monetary valuation for ecosystem impacts is not possible using the ExternE methodology at present. The Meri-Pori power station representing the coal fuel cycle is one of the world's cleanest and most efficient coal-fired power plants with a condensing turbine. The coal is imported mainly from Poland. The estimated health damages were about 4 mECU/kWh, crop damages an order of magnitude lower and damages caused to building materials two orders of magnitude lower. The power stations of the peat and biomass fuel cycles are of CHP type, generating electricity and heat for the district heating systems of two cities. Their fuels are of domestic origin. The estimated health damages allocated to electricity generation were about 5 and 6 mECU/kWh, respectively. The estimates were case-specific and thus an generalisation of the results to the whole electricity generation in Finland is unrealistic. Despite the uncertainties and limitations of the methodology, it is a promising tool in the comparison of similar kinds of fuel cycles, new power plants and pollution abatement technologies and different plant locations with each other. (orig.)

  11. Lessons learned from external hazards

    Energy Technology Data Exchange (ETDEWEB)

    Peinador, Miguel; Zerger, Benoit [European Commisison Joint Research Centre, Petten (Netherlands). Inst. for Energy and Transport; Ramos, Manuel Martin [European Commission Joint Research Centre, Brussels (Belgium). Nuclear Safety and Security Coordination; Wattrelos, Didier [Institut de Radioprotection et de Surete Nucleaire (IRSN), Fontenay-aux-Roses (France); Maqua, Michael [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, Koeln (Germany)

    2014-01-15

    This paper presents a study performed by the European Clearinghouse of the Joint Research Centre on Operational Experience for nuclear power plants in cooperation with IRSN and GRS covering events reported by nuclear power plants in relation to external hazards. It summarizes the review of 235 event reports from 3 different databases. The events were grouped in 9 categories according to the nature of the external hazard involved, and the specific lessons learned and recommendations that can be derived from each of these categories are presented. Additional 'cross-cutting' recommendations covering several or all the external hazards considered are also discussed. These recommendations can be useful in preventing this type of events from happening again or in limiting their consequences. The study was launched in 2010 and therefore it does not cover the Fukushima event. This paper presents the main findings and recommendations raised by this study. (orig.)

  12. Clinical efficacy and safety of limited internal fixation combined with external fixation for Pilon fracture: A systematic review and meta-analysis

    OpenAIRE

    Zhang, Shaobo; Zhang, Yibao; Wang, Shenghong; Zhang, Hua; Liu, Peng; Zhang, Wei; Ma, Jing-Lin; Wang, Jing

    2017-01-01

    Purpose: To compare the clinical efficacy and complications of limited internal fixation combined with external fixation (LIFEF) and open reduction and internal fixation (ORIF) in the treatment of Pilon fracture. Methods: We searched databases including Pubmed, Embase, Web of science, Cochrane Library and China Biology Medicine disc for the studies comparing clinical efficacy and complications of LIFEF and ORIF in the treatment of Pilon fracture. The clinical efficacy was evaluated by the ...

  13. External Otitis (Swimmer's Ear)

    Science.gov (United States)

    ... otitis. Fungal external otitis (otomycosis), typically caused by Aspergillus niger or Candida albicans, is less common. Boils are ... in the ear. Fungal external otitis caused by Aspergillus niger usually causes grayish black or yellow dots (called ...

  14. ExternE: Externalities of energy Vol. 2. Methodology

    International Nuclear Information System (INIS)

    Berry, J.; Holland, M.; Watkiss, P.

    1995-01-01

    This report describes the methodology used by the ExternE Project of the European Commission (DGXII) JOULE Programme for assessment of the external costs of energy. It is one of a series of reports describing analysis of nuclear, fossil and renewable fuel cycles for assessment of the externalities associated with electricity generation. Part I of the report deals with analysis of impacts, and Part II with the economic valuation of those impacts. Analysis is conducted on a marginal basis, to allow the effect of an incremental investment in a given technology to be quantified. Attention has been paid to the specificity of results with respect to the location of fuel cycle activities, the precise technologies used, and the type and source of fuel. The main advantages of this detailed approach are as follows: It takes full and proper account of the variability of impacts that might result from different power projects; It is more transparent than analysis based on hypothetically 'representative' cases for each of the different fuel cycles; It provides a framework for consistent comparison between fuel cycles. A wide variety of impacts have been considered. These include the effects of air pollution on the natural and human environment, consequences of accidents in the workplace, impacts of noise and visual intrusion on amenity, and the effects of climate change arising from the release of greenhouse gases. Wherever possible we have used the 'impact pathway' or 'damage function' approach to follow the analysis from identification of burdens (e.g. emissions) through to impact assessment and then valuation in monetary terms. This has required a detailed knowledge of the technologies involved, pollutant dispersion, analysis of effects on human and environmental health, and economics. In view of this the project brought together a multi-disciplinary team with experts from many European countries and the USA. The spatial and temporal ranges considered in the analysis are

  15. ASH External Web Portal (External Portal) -

    Data.gov (United States)

    Department of Transportation — The ASH External Web Portal is a web-based portal that provides single sign-on functionality, making the web portal a single location from which to be authenticated...

  16. Leveraging External Sources of Innovation

    DEFF Research Database (Denmark)

    West, Joel; Bogers, Marcel

    2014-01-01

    , it suggests a four-phase model in which a linear process—(1) obtaining, (2) integrating, and (3) commercializing external innovations—is combined with (4) interaction between the firm and its collaborators. This model is used to classify papers taken from the top 25 innovation journals, complemented by highly...... cited work beyond those journals. A review of 291 open innovation-related publications from these sources shows that the majority of these articles indeed address elements of this inbound open innovation process model. Specifically, it finds that researchers have front-loaded their examination...... external innovations create value rather than how firms capture value from those innovations. Finally, the interaction phase considers both feedback for the linear process and reciprocal innovation processes such as cocreation, network collaboration, and community innovation. This review and synthesis...

  17. Parasitic infections of the external eye.

    Science.gov (United States)

    Pahuja, Shivani; Puranik, Charuta; Jelliti, Bechir; Khairallah, Moncef; Sangwan, Virender S

    2013-08-01

    To review the published literature on parasitic infections of external eye. Published articles and case reports on parasitic infections of external eye were reviewed and relevant information was collected. Parasitic infections of the eye are rare. However, being more commonly seen in developing nations, they require active measures for screening, diagnosis, and therapy. Parasites of importance causing external ocular disease are protozoan parasites, such as Leishmania; metazoans, such as nematodes (roundworms), cestodes (tapeworms), and trematodes (flatworms); or ectoparasites, such as Phthirus pubis and Demodex.

  18. International Expert Review of Sr-Can: Safety Assessment Methodology - External review contribution in support of SSI's and SKI's review of SR-Can

    Energy Technology Data Exchange (ETDEWEB)

    Sagar, Budhi (Center for Nuclear Waste Regulatory Analyses, Southwest Research Inst., San Antonio, TX (US)); Egan, Michael (Quintessa Limited, Henley-on-Thames (GB)); Roehlig, Klaus-Juergen (Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (DE)); Chapman, Neil (Independent Consultant (XX)); Wilmot, Roger (Galson Sciences Limited, Oakham (GB))

    2008-03-15

    In 2006, SKB published a safety assessment (SR-Can) as part of its work to support a licence application for the construction of a final repository for spent nuclear fuel. The purposes of the SR-Can project were stated in the main project report to be: 1. To make a first assessment of the safety of potential KBS-3 repositories at Forsmark and Laxemar to dispose of canisters as specified in the application for the encapsulation plant. 2. To provide feedback to design development, to SKB's research and development (R and D) programme, to further site investigations and to future safety assessments. 3. To foster a dialogue with the authorities that oversee SKB's activities, i.e. the Swedish Nuclear Power Inspectorate, SKI, and the Swedish Radiation Protection Authority, SSI, regarding interpretation of applicable regulations, as a preparation for the SR-Site project. To help inform their review of SKB's proposed approach to development of the longterm safety case, the authorities appointed three international expert review teams to carry out a review of SKB's SR-Can safety assessment report. Comments from one of these teams - the Safety Assessment Methodology (SAM) review team - are presented in this document. The SAM review team's scope of work included an examination of SKB's documentation of the assessment ('Long-term safety for KBS-3 Repositories at Forsmark and Laxemar - a first evaluation' and several supporting reports) and hearings with SKB staff and contractors, held in March 2007. As directed by SKI and SSI, the SAM review team focused on methodological aspects and sought to determine whether SKB's proposed safety assessment methodology is likely to be suitable for use in the future SR-Site and to assess its consistency with the Swedish regulatory framework. No specific evaluation of long-term safety or site acceptability was undertaken by any of the review teams. SKI and SSI's Terms of Reference for the SAM

  19. International Expert Review of SRCan: Site Investigation Aspects. External review contribution in support of SKI's and SSI's review of SR-Can. INSITE/OVERSITE

    Energy Technology Data Exchange (ETDEWEB)

    2008-03-15

    As a first evaluation of long-term safety for KBS-3 repositories at Forsmark and Laxemar, the SIG (Site Investigation Group) found SR-Can to be a well-produced and generally well-argued safety assessment. Overall, SKB is to be complimented on this project. Members of of the two groups INSITE and OVERSITE within the SIG had somewhat differing views on how well SKB had made use of the site data available at the end of the SDM 1.2 stage of investigations. This difference is less to do with the extent of site characterisation than of its use and application, reflecting the different levels of maturity of SKB's geosphere and biosphere assessment programmes. The more recent and current work on the sites means that our concerns expressed in this review should, to a large extent, be addressable in or prior to SR-Site, provided SKB is so minded. However, we acknowledge that some of the issues we raise will not be fully resolved until underground rock characterisation from excavations or longer records of surface conditions are available. There are also some key aspects of SKB's methodology still under development that would benefit from review prior to their use in SR-Site. More space in the currently pressing schedule would allow for this review and a consequent increase in confidence. In any case, the authorities should be aware that SKB may face residual programmatic risks, associated principally with the underground design and layout (and their knockon effects into performance), even after SR-Site. An early understanding of some of these relationships would be helped by a plan (at least on an outline level) of the underground characterisation programme. We also note that many engineering matters are still to be confronted, not least the EBS design and its implementation, along with the treatment of high stresses, if Forsmark is selected. However, our views on the nature of the SR-Can analysis and the way in which site data have been utilised in it (our

  20. Sludge Washing and Demonstration of the DWPF Nitric/Formic Flowsheet in the SRNL Shielded Cells for Sludge Batch 9 Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Pareizs, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Newell, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Martino, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Crawford, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Johnson, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-11-01

    Savannah River National Laboratory (SRNL) was requested by Savannah River Remediation (SRR) to qualify the next batch of sludge – Sludge Batch 9 (SB9). Current practice is to prepare sludge batches in Tank 51 by transferring sludge to Tank 51 from other tanks. The sludge is washed and transferred to Tank 40, the current Defense Waste Process Facility (DWPF) feed tank. Prior to sludge transfer from Tank 51 to Tank 40, the Tank 51 sludge must be qualified. SRNL qualifies the sludge in multiple steps. First, a Tank 51 sample is received, then characterized, washed, and again characterized. SRNL then demonstrates the DWPF Chemical Process Cell (CPC) flowsheet with the sludge. The final step of qualification involves chemical durability measurements of glass fabricated in the DWPF CPC demonstrations. In past sludge batches, SRNL had completed the DWPF demonstration with Tank 51 sludge. For SB9, SRNL has been requested to process a blend of Tank 51 and Tank 40 at a targeted ratio of 44% Tank 51 and 56% Tank 40 on an insoluble solids basis.

  1. Review of SR-Can: Evaluation of SKB's handling of spent fuel performance, radionuclide chemistry and geosphere transport parameters. External review contribution in support of SKI's and SSI's review of SR-Can

    International Nuclear Information System (INIS)

    Stenhouse, Mike; Jegou, Christophe; Brown, Paul; Meinrath, Guenther; Nitsche, Heino; Ekberg, Christian

    2008-03-01

    SR-Can covers the containment phase of the KBS-3 barriers as well as the consequences of releases of radionuclides to the rock and eventually the biosphere (after complete containment within fuel canisters has partially failed). The aim of this report is to provide a range of review comments with respect to those parameters related to spent fuel performance as well as radionuclide chemistry and transport. These parameter values are used in the quantification of consequences due to release of radionuclides from potentially leaking canisters. The report does not cover modelling approaches used for quantification of consequences. However, modelling used to derive parameter values is to some extent addressed (such as calculation of maximum radionuclide concentration due to formation of solubility limiting phases). The following are the key highlights and comments generated in the course of the review: Inconsistencies exist between recommendations provided in technical reports and those quoted in the Data Report. One of the reasons for such inconsistencies has been the timing of different pieces of research. It is hoped that the timing of contributions to SR-Site will be such that these inconsistencies can be avoided. Sensitivity analyses need to be carried out and reported in a number of areas to support some of the assumptions or decisions made in the assessment calculations. The likelihood is that SKB has performed many of the sensitivity analyses identified in different parts of this report, but these need to be reported, preferably to complement the recommendations provided

  2. External radiation surveillance

    International Nuclear Information System (INIS)

    Antonio, E.J.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report describes how external radiation was measured, how surveys were performed, and the results of these measurements and surveys. External radiation exposure rates were measured at locations on and off the Hanford Site using thermoluminescent dosimeters (TLD). External radiation and contamination surveys were also performed with portable radiation survey instruments at locations on and around the Hanford Site

  3. External radiation surveillance

    Energy Technology Data Exchange (ETDEWEB)

    Antonio, E.J.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report describes how external radiation was measured, how surveys were performed, and the results of these measurements and surveys. External radiation exposure rates were measured at locations on and off the Hanford Site using thermoluminescent dosimeters (TLD). External radiation and contamination surveys were also performed with portable radiation survey instruments at locations on and around the Hanford Site.

  4. ExternE: Externalities of energy Vol. 5. Nuclear

    International Nuclear Information System (INIS)

    Dreicer, M.; Tort, V.; Manen, P.

    1995-01-01

    Since the early 1970s, there has been increased interest in the environmental impacts that are caused by the generation of electricity. The comparative risk assessment studies at that time used mainly deaths and injuries as impact indicators. By the end of the 1980s studies changed to the assessment of the costs imposed on society and the environment that were not included in the market price of the energy produced, the so-called external costs. The preliminary studies that were published set the conceptual basis, grounded in neo-classical economics, for the valuation of the health and environmental impacts that could be assessed. As a consequence of the many questions raised by the methodologies employed by these early studies, Directorate General XII (DG XII) of the Commission of the European Communities established a collaborative research programme with the United States Department of Energy to identify an appropriate methodology for this type of work. Following the completion of this collaboration, the DG XII programme has continued as the ExternE project. The main objective of the work carried out at CEPN was to develop an impact pathway methodology for the nuclear fuel cycle that would be consistent with the methodologies developed for other fuel cycles, without loosing the nuclear-specific techniques required for a proper evaluation. In this way, comparisons between the different fuel cycles would be possible. This report presents the methodology and demonstration of the results in the context of the French nuclear fuel cycle. The United States team at Oak Ridge National Laboratory has previously issued a draft report on the results of their assessment. The French fuel cycle was broken down into 8 separate stages. Reference sites and 1990s technology were chosen to represent the total nuclear fuel cycle, as it exists today. In addition, the transportation of material between the sites was considered. The facilities are assessed for routine operation, except

  5. Effects of After-School Programs on Attendance and Externalizing Behaviors with Primary and Secondary School Students: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    Maynard, Brandy R.; Kremer, Kristen P.; Polanin, Joshua R.; Vaughn, Michael G.; Sarteschi, Christine M.

    2015-01-01

    Over the past two decades, the number and types of after-school programs (ASPs) have increased substantially as a result of increased federal and private spending and because ASPs are perceived to provide wide-ranging and far-reaching benefits to students, families, schools and the public. The purpose of this systematic review and meta-analysis is…

  6. An Assessment of Decision-Making Processes: The Feasibility of Incorporating Climate Change Information into Land Protection Planning (External Review Draft)

    Science.gov (United States)

    This report was prepared by the Global Change Research Program (GCRP) in the National Center for Environmental Assessment (NCEA) of the Office of Research and Development (ORD) at the U.S. Environmental Protection Agency (EPA). This draft report is a review of decision-making pro...

  7. External Peer Review Team Report for Corrective Action Unit 97: Yucca Flat/Climax Mine, Nevada National Security Site, Nye County, Nevada, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Marutzky, Sam J. [Navarro-Intera, LLC (N-I), Las Vegas, NV (United States); Andrews, Robert [Navarro-Intera, LLC (N-I), Las Vegas, NV (United States)

    2015-01-01

    The peer review team commends the Navarro-Intera, LLC (N-I), team for its efforts in using limited data to model the fate of radionuclides in groundwater at Yucca Flat. Recognizing the key uncertainties and related recommendations discussed in Section 6.0 of this report, the peer review team has concluded that U.S. Department of Energy (DOE) is ready for a transition to model evaluation studies in the corrective action decision document (CADD)/corrective action plan (CAP) stage. The DOE, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) clarified the charge to the peer review team in a letter dated October 9, 2014, from Bill R. Wilborn, NNSA/NFO Underground Test Area (UGTA) Activity Lead, to Sam J. Marutzky, N-I UGTA Project Manager: “The model and supporting information should be sufficiently complete that the key uncertainties can be adequately identified such that they can be addressed by appropriate model evaluation studies. The model evaluation studies may include data collection and model refinements conducted during the CADD/CAP stage. One major input to identifying ‘key uncertainties’ is the detailed peer review provided by independent qualified peers.” The key uncertainties that the peer review team recognized and potential concerns associated with each are outlined in Section 6.0, along with recommendations corresponding to each uncertainty. The uncertainties, concerns, and recommendations are summarized in Table ES-1. The number associated with each concern refers to the section in this report where the concern is discussed in detail.

  8. Review of SKB's Work on Coupled THM Processes Within SR-Can. External review contribution in support of SKI's and SSI's review of SR-Can

    Energy Technology Data Exchange (ETDEWEB)

    Rutqvist, Jonny; Chin-Fu Tsang (Lawrence Berkeley National Laboratory, Berkeley, CA (US))

    2008-03-15

    In this report, we scrutinize the work by the Swedish Nuclear Fuel and Waste Management Company (SKB) related to coupled thermal, hydrological and mechanical (THM) processes within the SR-Can project. SR-Can is SKB's preliminary assessment of long-term safety for a KBS-3 nuclear waste repository, and is a preparation stage for the SR-Site assessment, the report that will be used in SKB's application for a final repository. We scrutinize SKB's work related to THM processes through review and detailed analysis, using an independent modeling tool. The modeling tool is applied to analyze coupled THM processes at the two candidate sites, Forsmark and Laxemar, using data defined in SKB's site description models for respective sites. In this report, we first provide a brief overview of SKB's work related to analysis of the evolution of coupled THM processes as presented in SRCan, as well as supporting documents. In this overview we also identify issues and assumptions that we then analyze using our modeling tool. The overview and subsequent independent model analysis addresses issues related to near-field behavior, such as buffer resaturation and the evolution of the excavation-disturbed zone, as well as far-field behavior, such as stress induced changes in hydrologic properties. Based on the review and modeling conducted in this report, we conclude by identifying a number of areas of weaknesses, where we believe further work and clarifications are needed. Some of the most important ones are summarized below: 1) We found that SKB's calculation of peak temperature might not have been conducted for the most conservative case of extreme drying of the buffer under dry rock conditions and an unexpectedly high thermal diffusion coefficient. Our alternative analysis indicates that temperatures close to 100 might be achieved under unfavorable (and perhaps unexpected) conditions in which the buffer is dried to below 20% near the canister. We believe

  9. Evaluation of interim and final waste forms for the newly generated liquid low-level waste flowsheet

    International Nuclear Information System (INIS)

    Abotsi, G.M.K.; Bostick, D.T.; Beck, D.E.

    1996-05-01

    The purpose of this review is to evaluate the final forms that have been proposed for radioactive-containing solid wastes and to determine their application to the solid wastes that will result from the treatment of newly generated liquid low-level waste (NGLLLW) and Melton Valley Storage Tank (MVST) supernate at the Oak Ridge National Laboratory (ORNL). Since cesium and strontium are the predominant radionuclides in NGLLLW and MVST supernate, this review is focused on the stabilization and solidification of solid wastes containing these radionuclides in cement, glass, and polymeric materials-the principal waste forms that have been tested with these types of wastes. Several studies have shown that both cesium and strontium are leached by distilled water from solidified cement, although the leachabilities of cesium are generally higher than those of strontium under similar conditions. The situation is exacerbated by the presence of sulfates in the solution, as manifested by cracking of the grout. Additives such as bentonite, blast-furnace slag, fly ash, montmorillonite, pottery clay, silica, and zeolites generally decrease the cesium and strontium release rates. Longer cement curing times (>28 d) and high ionic strengths of the leachates, such as those that occur in seawater, also decrease the leach rates of these radionuclides. Lower cesium leach rates are observed from vitrified wastes than from grout waste forms. However, significant quantities of cesium are volatilized due to the elevated temperatures required to vitrify the waste. Hence, vitrification will generally require the use of cleanup systems for the off-gases to prevent their release into the atmosphere

  10. Clinical efficacy and safety of limited internal fixation combined with external fixation for Pilon fracture: A systematic review and meta-analysis.

    Science.gov (United States)

    Zhang, Shao-Bo; Zhang, Yi-Bao; Wang, Sheng-Hong; Zhang, Hua; Liu, Peng; Zhang, Wei; Ma, Jing-Lin; Wang, Jing

    2017-04-01

    To compare the clinical efficacy and complications of limited internal fixation combined with external fixation (LIFEF) and open reduction and internal fixation (ORIF) in the treatment of Pilon fracture. We searched databases including Pubmed, Embase, Web of science, Cochrane Library and China Biology Medicine disc for the studies comparing clinical efficacy and complications of LIFEF and ORIF in the treatment of Pilon fracture. The clinical efficacy was evaluated by the rate of nonunion, malunion/delayed union and the excellent/good rate assessed by Mazur ankle score. The complications including infections and arthritis symptoms after surgery were also investigated. Nine trials including 498 pilon fractures of 494 patients were identified. The meta-analysis found no significant differences in nonunion rate (RR = 1.60, 95% CI: 0.66 to 3.86, p = 0.30), and the excellent/good rate (RR = 0.95, 95% CI: 0.86 to 1.04, p = 0.28) between LIFEF group and ORIF group. For assessment of infections, there were significant differences in the rate of deep infection (RR = 2.18, 95% CI: 1.34 to 3.55, p = 0.002), and the rate of arthritis (RR = 1.26, 95% CI: 1.03 to 1.53, p = 0.02) between LIFEF group and ORIF group. LIFEF has similar effect as ORIF in the treatment of pilon fractures, however, LIFEF group has significantly higher risk of complications than ORIF group does. So LIFEF is not recommended in the treatment of pilon fracture. Copyright © 2017 Daping Hospital and the Research Institute of Surgery of the Third Military Medical University. Production and hosting by Elsevier B.V. All rights reserved.

  11. A Methodology Proposal to Calculate the Externalities of Liquid Biofuels

    Energy Technology Data Exchange (ETDEWEB)

    Galan, A.; Gonzalez, R.; Varela, M. [Ciemat. Madrid (Spain)

    1999-05-01

    The aim of the survey is to propose a methodology to calculate the externalities associated with the liquid bio fuels cycle. The report defines the externalities from a theoretical point of view and classifies them. The reasons to value the externalities are explained as well as the existing methods. Furthermore, an evaluation of specific environmental and non-environmental externalities is also presented. The report reviews the current situation of the transport sector, considering its environmental effects and impacts. The progress made by the ExternE and ExternE-transport projects related the externalities of transport sector is assessed. Finally, the report analyses the existence of different economic instruments to internalize the external effects of the transport sector as well as other aspects of this internalization. (Author) 58 refs.

  12. [External cephalic version].

    Science.gov (United States)

    Navarro-Santana, B; Duarez-Coronado, M; Plaza-Arranz, J

    2016-08-01

    To analyze the rate of successful external cephalic versions in our center and caesarean sections that would be avoided with the use of external cephalic versions. From January 2012 to March 2016 external cephalic versions carried out at our center, which were a total of 52. We collected data about female age, gestational age at the time of the external cephalic version, maternal body mass index (BMI), fetal variety and situation, fetal weight, parity, location of the placenta, amniotic fluid index (ILA), tocolysis, analgesia, and newborn weight at birth, minor adverse effects (dizziness, hypotension and maternal pain) and major adverse effects (tachycardia, bradycardia, decelerations and emergency cesarean section). 45% of the versions were unsuccessful and 55% were successful. The percentage of successful vaginal delivery in versions was 84% (4% were instrumental) and 15% of caesarean sections. With respect to the variables studied, only significant differences in birth weight were found; suggesting that birth weight it is related to the outcome of external cephalic version. Probably we did not find significant differences due to the number of patients studied. For women with breech presentation, we recommend external cephalic version before the expectant management or performing a cesarean section. The external cephalic version increases the proportion of fetuses in cephalic presentation and also decreases the rate of caesarean sections.

  13. Piezosurgery in External Dacryocystorhinostomy.

    Science.gov (United States)

    Czyz, Craig N; Fowler, Amy M; Dutton, Jonathan J; Cahill, Kenneth V; Foster, Jill A; Hill, Robert H; Everman, Kelly R; Nabavi, Cameron B

    Dacryocystorhinostomy (DCR) can be performed via an external or endoscopic approach. The use of ultrasonic or piezosurgery has been well described for endoscopic DCRs but is lacking for external DCRs. This study presents a case series of external DCRs performed using piezosurgery evaluating results and complications. Prospective, consecutive case series of patients undergoing primary external DCR for lacrimal drainage insufficiency. A standard external DCR technique was used using 1 of 2 piezosurgery systems for all bone incision. All patients received silicone intubation to the lacrimal system. Surgical outcome was measured in terms of patient-reported epiphora as follows: 1) complete resolution, 2) improvement >50%, 3) improvement 50% improvement. There were 4 patients (7%) who had <50% improvement. There was 1 (2%) intraoperative complication and 2 (4%) postoperative complications recorded. Piezourgery is a viable modality for performing external DCRs. The lack of surgical complications shows a potential for decreased soft tissues damage. The surgical success rate based on patient-reported epiphora is similar to those published for mechanical external DCRs. This modality may benefit the novice surgeon in the reduction of soft and mucosal tissue damage.

  14. Review of declarations received by the AFSSAPS and the ASN on the account of radio-vigilance (external radiotherapy). July 2007 - June 2008

    International Nuclear Information System (INIS)

    2009-09-01

    After a presentation of the procedure of declaration of significant radiation protection events, of the ASN-SFRO event scale, and of the indication procedure related to material vigilance, this report proposes a review and an analysis of significant radioprotection and material vigilance events which have been declared between July 2007 and June 2008. The assessment of radiation protection events declared to the ASN is as well quantitative (distribution in time, geographical distribution, status of declaring centres, declaration delays, classification according to the ASN-SFRO scale) as qualitative (origin, event typology, stage of the treatment process at which the event occurred and has been detected, personnel having detected the event, communication about events). The analysis of material vigilance events addresses the evolution of their number, their distribution in terms of declarer type, of radiotherapy equipment, or of criticality level, and so on. A review of hybrid accidents is proposed (concerned equipment, declarer origin, consequences of the declarations, classification on the ASN-SFRO scale)

  15. Evaluation of orthodontically induced external root resorption following orthodontic treatment using cone beam computed tomography (CBCT): a systematic review and meta-analysis.

    Science.gov (United States)

    Samandara, Aikaterini; Papageorgiou, Spyridon N; Ioannidou-Marathiotou, Ioulia; Kavvadia-Tsatala, Smaragda; Papadopoulos, Moschos A

    2018-05-15

    Orthodontically induced external root resorption (OIRR) is a pathologic consequence of orthodontic tooth movement. However, the limitations of two-dimensional radiography suggest that cone beam computed tomography (CBCT) with its three-dimensional capabilities might be more suitable to assess OIRR. The aim of this study was to assess in an evidence-based manner data on linear or volumetric OIRR measurements of permanent teeth by means of CBCT, during and/or after the end of orthodontic treatment. Unrestricted electronic and hand searches were performed up to January 2017 in 15 databases. Randomized clinical trials, prospective, and retrospective non-randomized studies assessing OIRR during and/or after orthodontic treatment using CBCT in human patients were included. After duplicate study selection, data extraction, and risk-of-bias assessment according to the Cochrane guidelines, random-effects meta-analyses, followed by subgroup, meta-regression, and sensitivity analyses were also performed in order to evaluate factors that affect OIRR. A total of 33 studies (30 datasets) were included in the qualitative analysis while data from 27 of them were included in the quantitative analysis. Direct comparisons from randomized trials found little to no influence of appliance-related factors on OIRR. Explorative analyses including non-randomized studies found a pooled OIRR of 0.79 mm based on all included studies and 0.86 mm when OIRR was assessed at the end of orthodontic treatment. Statistically significant differences in OIRR were found according to tooth type or jaw, inclusion of extractions, treatment duration, and diagnostic accuracy of the CBCT. Based on the results of this study, CBCT seems to be a reliable tool to examine OIRR during or at the end of orthodontic treatment. Although the average OIRR measured with CBCT seems to lack clinical relevance, there are certain factors that may affect OIRR following orthodontic treatment. Nevertheless, due to data

  16. Automated External Defibrillator

    Science.gov (United States)

    ... leads to a 10 percent reduction in survival. Training To Use an Automated External Defibrillator Learning how to use an AED and taking a CPR (cardiopulmonary resuscitation) course are helpful. However, if trained ...

  17. Energy policy and externalities

    International Nuclear Information System (INIS)

    Bertel, E.; Fraser, P.

    2002-01-01

    External costs of energy have been assessed in a number of authoritative and reliable studies based upon widely accepted methodologies such as life cycle analysis (LCA). However, although those costs are recognised by most stakeholders and decision makers, results from analytical work on externalities and LCA studies are seldom used in policy making. The International Energy Agency (IEA) and the Nuclear Energy Agency (NEA) convened a joint workshop in November 2001 to offer experts and policy makers an opportunity to present state-of-the-art results from analytical work on externalities and debate issues related to the relevance of external costs and LCA for policy-making purposes. The findings from the workshop highlight the need for further work in the field and the potential rote of international organisations like the IEA and the NEA in this context. (authors)

  18. Externally Verifiable Oblivious RAM

    Directory of Open Access Journals (Sweden)

    Gancher Joshua

    2017-04-01

    Full Text Available We present the idea of externally verifiable oblivious RAM (ORAM. Our goal is to allow a client and server carrying out an ORAM protocol to have disputes adjudicated by a third party, allowing for the enforcement of penalties against an unreliable or malicious server. We give a security definition that guarantees protection not only against a malicious server but also against a client making false accusations. We then give modifications of the Path ORAM [15] and Ring ORAM [9] protocols that meet this security definition. These protocols both have the same asymptotic runtimes as the semi-honest original versions and require the external verifier to be involved only when the client or server deviates from the protocol. Finally, we implement externally verified ORAM, along with an automated cryptocurrency contract to use as the external verifier.

  19. ExternE: Externalities of energy Vol. 4. Oil and gas

    International Nuclear Information System (INIS)

    Friedrich, R.; Krewitt, W.; Mayerhofer, P.

    1995-01-01

    methodological issues was reached on both sides of the Atlantic. Since 1993 the study has continued in Europe as the ExternE-Project, and now involves an international team of more than 30 organisations. The current study has three main objectives: 1. to identify and develop a suitable methodology with which to quantify the external costs and benefits of the major fuel cycles for electricity generation and conservation, using the best available models and data. This is to be done using a common framework for assessment of different fuel cycles, in order that fair comparison can be made between them; 2. to use this methodology to assess the external costs for a number of case studies representative of each fuel cycle; 3. to make recommendations on areas in which further research is required in order that future estimates of damages can be made with greater confidence. This document assesses the progress made in quantifying environmental and health damages associated with the oil and the natural gas fuel cycles. Estimates of impacts have been made following critical review of existing data and models rather than from original basic research. This review has been performed by a multi-disciplinary team including specialists in the fields of health, forestry, ecology, materials science, atmospheric chemistry and physics. energy technology, computer science and economics. The methodology developed in the ExternE Project is described in more detail elsewhere (European Commission. 1995a). Wherever possible we have used exactly the same methodology to quantify the same form of damage for each fuel cycle. However, some differences will be observed in the assessment of the fuel cycles considered in this report. These arise largely through the status of development of the methodology when certain parts of the work were completed. Wherever possible these differences have been resolved from a methodological perspective in the companion report (European Commission, 1995a)

  20. Literature Review: Assessment of DWPF Melter and Melter Off-gas System Lifetime

    Energy Technology Data Exchange (ETDEWEB)

    Reigel, M. [Savannah River Site (SRS), Aiken, SC (United States)

    2015-07-30

    Testing to date for the MOC for the Hanford Waste Treatment and Immobilization Plant (WTP) melters is being reviewed with the lessons learned from DWPF in mind and with consideration to the changes in the flowsheet/feed compositions that have occurred since the original testing was performed. This information will be presented in a separate technical report that identifies any potential gaps for WTP processing.

  1. External Environment and Upper Echelons Theory

    DEFF Research Database (Denmark)

    Escribá-Esteve, Alejandro; Nielsen, Sabina; Yamak, Sibel

    This work reviews empirical research on TMTs with a specific emphasis on the role of the external environment. We extend the existing research on upper echelons theory, which has largely focused on the team and firm level of analyses of top management teams (TMT). Considering institutional...... and industrial organization theories, we elaborate a cross-level conceptual model outlining the direct, mediating and moderating effects of the external environment on TMTs and their impact. Our review distinguishes between industry and institutional level of analyses and three types of environmental...

  2. DWPF SB6 Initial CPC Flowsheet Testing SB6-1 TO SB6-4L Tests Of SB6-A And SB6-B Simulants

    International Nuclear Information System (INIS)

    Lambert, D.; Pickenheim, B.; Best, D.

    2009-01-01

    The Defense Waste Processing Facility (DWPF) will transition from Sludge Batch 5 (SB5) processing to Sludge Batch 6 (SB6) processing in late fiscal year 2010. Tests were conducted using non-radioactive simulants of the expected SB6 composition to determine the impact of varying the acid stoichiometry during the Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) processes. The work was conducted to meet the Technical Task Request (TTR) HLW/DWPF/TTR-2008-0043, Rev.0 and followed the guidelines of a Task Technical and Quality Assurance Plan (TT and QAP). The flowsheet studies are performed to evaluate the potential chemical processing issues, hydrogen generation rates, and process slurry rheological properties as a function of acid stoichiometry. These studies were conducted with the estimated SB6 composition at the time of the study. This composition assumed a blend of 101,085 kg of Tank 4 insoluble solids and 179,000 kg of Tank 12 insoluble solids. The current plans are to subject Tank 12 sludge to aluminum dissolution. Liquid Waste Operations assumed that 75% of the aluminum would be dissolved during this process. After dissolution and blending of Tank 4 sludge slurry, plans included washing the contents of Tank 51 to ∼1M Na. After the completion of washing, the plan assumes that 40 inches on Tank 40 slurry would remain for blending with the qualified SB6 material. There are several parameters that are noteworthy concerning SB6 sludge: (1) This is the second batch DWPF will be processing that contains sludge that has had a significant fraction of aluminum removed through aluminum dissolution; (2) The sludge is high in mercury, but the projected concentration is lower than SB5; (3) The sludge is high in noble metals, but the projected concentrations are lower than SB5; and(4) The sludge is high in U and Pu - components that are not added in sludge simulants. Six DWPF process simulations were completed in 4-L laboratory-scale equipment using

  3. Malignant external otitis

    International Nuclear Information System (INIS)

    Dupuch, K.M.; Iryboz, T.; Firat, M.; Levy, C.; Tubiana, J.M.

    1991-01-01

    This paper illustrates the value of CT and MR in early diagnosis and spread of malignant external otitis. The authors retrospectively analyzed 15 patients with proved malignant external otitis examined with postcontrast high-resolution CT (15/15) and MR (6/15) (T1- and T2-weighting). Gallium studies were done in 6/15 patients. Early diagnosis was made when CT demonstrated a soft-tissue mass of the external auditory canal associated with scattered zones of cortical bone erosions (13/15). Spread of the disease was better delineated by MR than CT, especially skull base extension (6/15). Temporomandibular joint involvement with extension into parotid or/and masticator spaces 6/15 was as well detected with CT as with MR. If CT remains the first and best procedure for diagnosis, MR - despite its cost - appears a good procedure to depict exact anatomic spread, allowing therapeutic management

  4. Productivity Change and Externalities

    DEFF Research Database (Denmark)

    Kravtsova, Victoria

    2014-01-01

    This paper contributes to the analysis of the impact of externalities on the host country's total factor productivity by taking into account different dimensions of spillover effects. Namely, engagement in exporting and foreign ownership is generally perceived as being beneficial to individual...... firms and the economy as a whole. The approach used in the current research accounts for different internal as well as external factors that individual firms face and evaluates the effect on changes in productivity, technology as well as the efficiency of domestic firms. The empirical analysis focuses...... on Hungary. While the country leads the group of post-socialist countries in the amount of attracted foreign direct investments (FDI) the effect of this policy on the economy remains unclear. The research finds that different externalities play a different role in productivity, technological and efficiency...

  5. Externality or sustainability economics?

    International Nuclear Information System (INIS)

    Bergh, Jeroen C.J.M. van den

    2010-01-01

    In an effort to develop 'sustainability economics' Baumgaertner and Quaas (2010) neglect the central concept of environmental economics-'environmental externality'. This note proposes a possible connection between the concepts of environmental externality and sustainability. In addition, attention is asked for other aspects of 'sustainability economics', namely the distinction weak/strong sustainability, spatial sustainability and sustainable trade, distinctive sustainability policy, and the ideas of early 'sustainability economists'. I argue that both sustainability and externalities reflect a systems perspective and propose that effective sustainability solutions require that more attention is given to system feedbacks, notably other-regarding preferences and social interactions, and energy and environmental rebound. The case of climate change and policy is used to illustrate particular statements. As a conclusion, a list of 20 insights and suggestions for research is offered. (author)

  6. Metasurface external cavity laser

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Luyao, E-mail: luyaoxu.ee@ucla.edu; Curwen, Christopher A.; Williams, Benjamin S. [Department of Electrical Engineering, University of California, Los Angeles, California 90095 (United States); California NanoSystems Institute, University of California, Los Angeles, California 90095 (United States); Hon, Philip W. C.; Itoh, Tatsuo [Department of Electrical Engineering, University of California, Los Angeles, California 90095 (United States); Chen, Qi-Sheng [Northrop Grumman Aerospace Systems, Redondo Beach, California 90278 (United States)

    2015-11-30

    A vertical-external-cavity surface-emitting-laser is demonstrated in the terahertz range, which is based upon an amplifying metasurface reflector composed of a sub-wavelength array of antenna-coupled quantum-cascade sub-cavities. Lasing is possible when the metasurface reflector is placed into a low-loss external cavity such that the external cavity—not the sub-cavities—determines the beam properties. A near-Gaussian beam of 4.3° × 5.1° divergence is observed and an output power level >5 mW is achieved. The polarized response of the metasurface allows the use of a wire-grid polarizer as an output coupler that is continuously tunable.

  7. The External Mind

    DEFF Research Database (Denmark)

    , Extended Mind and Distributed Cognition by Claudio Paolucci pp. 69-96 The Social Horizon of Embodied Language and Material Symbols by Riccardo Fusaroli pp. 97-123 Semiotics and Theories of Situated/Distributed Action and Cognition: a Dialogue and Many Intersections by Tommaso Granelli pp. 125-167 Building......The External Mind: an Introduction by Riccardo Fusaroli, Claudio Paolucci pp. 3-31 The sign of the Hand: Symbolic Practices and the Extended Mind by Massimiliano Cappuccio, Michael Wheeler pp. 33-55 The Overextended Mind by Shaun Gallagher pp. 57-68 The "External Mind": Semiotics, Pragmatism...

  8. Material Compatibility Evaluation for DWPF Nitric-Glycolic Acid - Literature Review

    Energy Technology Data Exchange (ETDEWEB)

    Mickalonis, J. I. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Skidmore, T. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-09-30

    Glycolic acid is being evaluated as an alternative for formic and nitric acid in the DWPF flowsheet. Demonstration testing and modeling for this new flowsheet has shown that glycolic acid and glycolate has a potential to remain in certain streams generated during the production of the nuclear waste glass. A literature review was conducted to assess the impact of glycolic acid on the corrosion of the materials of construction for the DWPF facility as well as facilities downstream which may have residual glycolic acid and glycolates present. The literature data was limited to solutions containing principally glycolic acid. The reported corrosion rates and degradation characteristics have shown the following for the materials of construction.

  9. Externalities - an analysis using the EU ExternE-results

    International Nuclear Information System (INIS)

    2003-10-01

    The EU project ExternE quantified the externalities for the different energy technologies. In this work, the ExternE results are used in a MARKAL-analysis for the Nordic countries. The analysis does not go into detail, but gives some interesting indications: The external costs are not fully covered in the Nordic energy systems, the present taxes and charges are not high enough. The emissions from the energy systems would be strongly reduced, if taxes/environmental charges were set at the level ExternE calculate. The emissions from power production would be reduced most. Renewable energy sources and natural gas dominate the energy systems in the ExternE case

  10. External costs of electricity

    International Nuclear Information System (INIS)

    Rabl, A.; Spadaro, J.V.

    2005-01-01

    This article presents a synthesis of the ExternE project (External costs of Energy) of the European community about the external costs of power generation. Pollution impacts are calculated using an 'impact pathways' analysis, i.e. an analysis of the emission - dispersion - dose-response function - cost evaluation chain. Results are presented for different fuel cycles (with several technological variants) with their confidence intervals. The environmental impact costs are particularly high for coal: for instance, in France, for coal-fired power plants it is of the same order as the electricity retail price. For natural gas, this cost is about a third of the one for coal. On the contrary, the environmental impact costs for nuclear and renewable energies are low, typically of few per cent of the electricity price. The main part of these costs corresponds to the sanitary impacts, in particular the untimely mortality. In order to avoid any controversy about the cost evaluation of mortality, the reduction of the expectation of life due to the different fuel cycles is also indicated and the risks linked with nuclear energy are presented using several comparisons. (J.S.)

  11. On parabolic external maps

    DEFF Research Database (Denmark)

    Lomonaco, Luna; Petersen, Carsten Lunde; Shen, Weixiao

    2017-01-01

    We prove that any C1+BV degree d ≥ 2 circle covering h having all periodic orbits weakly expanding, is conjugate by a C1+BV diffeomorphism to a metrically expanding map. We use this to connect the space of parabolic external maps (coming from the theory of parabolic-like maps) to metrically expan...

  12. Stochastic Control - External Models

    DEFF Research Database (Denmark)

    Poulsen, Niels Kjølstad

    2005-01-01

    This note is devoted to control of stochastic systems described in discrete time. We are concerned with external descriptions or transfer function model, where we have a dynamic model for the input output relation only (i.e.. no direct internal information). The methods are based on LTI systems...

  13. Turbomachine Sealing and Secondary Flows - Part 3. Part 3; Review of Power-Stream Support, Unsteady Flow Systems, Seal and Disk Cavity Flows, Engine Externals, and Life and Reliability Issues

    Science.gov (United States)

    Hendricks, R. C.; Steinetz, B. M.; Zaretsky, E. V.; Athavale, M. M.; Przekwas, A. J.

    2004-01-01

    The issues and components supporting the engine power stream are reviewed. It is essential that companies pay close attention to engine sealing issues, particularly on the high-pressure spool or high-pressure pumps. Small changes in these systems are reflected throughout the entire engine. Although cavity, platform, and tip sealing are complex and have a significant effect on component and engine performance, computational tools (e.g., NASA-developed INDSEAL, SCISEAL, and ADPAC) are available to help guide the designer and the experimenter. Gas turbine engine and rocket engine externals must all function efficiently with a high degree of reliability in order for the engine to run but often receive little attention until they malfunction. Within the open literature statistically significant data for critical engine components are virtually nonexistent; the classic approach is deterministic. Studies show that variations with loading can have a significant effect on component performance and life. Without validation data they are just studies. These variations and deficits in statistical databases require immediate attention.

  14. ExternE: Externalities of energy Vol. 3. Coal and lignite

    International Nuclear Information System (INIS)

    Berry, J.; Holland, M.; Lee, D.

    1995-01-01

    methodological issues was reached on both sides of the Atlantic. Since 1993 the study has continued in Europe as the ExternE-Project, and now involves an international team of more than 30 organisations. The current study has three main objectives: 1. to design a unified methodology for quantifying the various social costs associated with the production and consumption of energy; 2. to use the methodology to evaluate the external costs of incremental use of different fuel cycles in different locations in the European Union; 3. to identify critical methodological issues and research requirements. At the same time as the publication of the present report, further reports are being published on the other major fuel cycles for electricity generation, including uranium, oil, gas, wind and hydro. A further volume, providing greater detail on the methodology used for assessment of the impacts of the fossil fuel cycles and their valuation is also being published. Additional reports on other fuel cycles, and implementation of the methodology in different countries will follow shortly. This document assesses the progress made in quantifying environmental and health damages associated with the coal and lignite fuel cycles. Estimates of impacts have been made following critical review of existing data and models rather than from original basic research. This review has been performed by a multi-disciplinary team including specialists in the fields of health, forestry, ecology, materials science, atmospheric chemistry and physics, energy technology, computer science and economics. Wherever possible we have used exactly the same methodology to quantify the same form of damage for each fuel cycle and for each location. However, some differences will be observed in the assessment of the fuel cycles considered in this report. These arise largely through the status of development of the methodology when certain parts of the work were completed. Wherever possible these differences have been

  15. ExternE transport methodology for external cost evaluation of air pollution

    DEFF Research Database (Denmark)

    Jensen, S. S.; Berkowicz, R.; Brandt, J.

    The report describes how the human exposure estimates based on NERI's human exposure modelling system (AirGIS) can improve the Danish data used for exposure factors in the ExternE Transport methodology. Initially, a brief description of the ExternE Tranport methodology is given and it is summarised...

  16. Development of a new miniature short-residence-time annular centrifugal solvent extraction contactor for tests of process flowsheets in hot cells

    International Nuclear Information System (INIS)

    Lanoe, J.Y.; Rivalier, P.

    2000-01-01

    Researches undertaken on new nuclear fuel reprocessing extraction processes need tests of process flowsheets in hot cells. To this goal, a new miniature short residence-time annular centrifugal solvent extraction contactor was conceived and developed at Marcoule. This single stage contactor is composed of an outer stationary cylinder (made of transparent plexiglas on prototype and of stainless steel on models for hot cells) and a suspended inner rotating cylinder of stainless steel; the inside diameter of the rotor is 12 mm. Aqueous and organic phases are fed into the gap between the two cylinders. The mixture flows down the annular space and then up through an orifice at the bottom of the rotor. Into the rotor, the emulsion breaks rapidly under the centrifugal force (up to 600 g with rotor speed of 10,000 rpm). The separated phases flow over their weirs and discharge at the top in their collector rings. The liquid hold-up of this centrifugal contactor is approximately 6 mL. The use in hots cells needed original designs for: - the assembly of a single-stage contactor: every part (motor, rotor, stationary housing) is simply inserted on the other one without screws and nuts; - the assembly of multistage group: every stage is stacking in two rails and an intermediate part (supported on the two rails) links exit ports and their corresponding inlet ports. All the parts are pressed and sealed against a terminal plate with a screw. Separating capacity tests with. a prototype were conducted using water as the aqueous phase and hydrogenated tetra-propylene (TPH) as the organic phase with aqueous to organic (A/O) flow ratio equal to 1. The best performances were obtained with rotor speed ranging from 4000 to 5000 rpm; the total throughput was then up to 2 L.h -1 . For a total throughput of 300 mL.h -1 , the hold-up in the annular mixing zone varied from 0.5 to 1.5 mL according to the A/O ratio and the starting mode. A number of tests were also performed to measure the

  17. CT of the external auditory canal: Correlation with clinical otoscopy

    International Nuclear Information System (INIS)

    Shankar, L.; Hawke, M.; Leekam, R.N.

    1987-01-01

    CT is the modality of choice in the assessment of external auditory canal abnormalities. Disorders of the complex structures within the ear that may be difficult to define clinically are well visualized on high-resolution CT. This exhibit illustrates various external auditory canal abnormalities and correlates these with color illustrations from clinical otoscopy. Congenital lesions of the external auditory canal - microtia, temporo-bandibular joint herniation, and fistulas - and various acquired lesions - traumatic, inflammatory, and neoplastic - are reviewed in this exhibit

  18. Crystal growth under external electric fields

    International Nuclear Information System (INIS)

    Uda, Satoshi; Koizumi, Haruhiko; Nozawa, Jun; Fujiwara, Kozo

    2014-01-01

    This is a review article concerning the crystal growth under external electric fields that has been studied in our lab for the past 10 years. An external field is applied electrostatically either through an electrically insulating phase or a direct injection of an electric current to the solid-interface-liquid. The former changes the chemical potential of both solid and liquid and controls the phase relationship while the latter modifies the transport and partitioning of ionic solutes in the oxide melt during crystallization and changes the solute distribution in the crystal

  19. Crystal growth under external electric fields

    Energy Technology Data Exchange (ETDEWEB)

    Uda, Satoshi; Koizumi, Haruhiko; Nozawa, Jun; Fujiwara, Kozo [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan)

    2014-10-06

    This is a review article concerning the crystal growth under external electric fields that has been studied in our lab for the past 10 years. An external field is applied electrostatically either through an electrically insulating phase or a direct injection of an electric current to the solid-interface-liquid. The former changes the chemical potential of both solid and liquid and controls the phase relationship while the latter modifies the transport and partitioning of ionic solutes in the oxide melt during crystallization and changes the solute distribution in the crystal.

  20. [External cephalic version of breech presentation at term].

    Science.gov (United States)

    Albrechtsen, Susanne; Berge, Lillian N; Børdahl, Per E; Egeland, Thore; Henriksen, Tore; Håheim, Lise Lund; Øian, Pål

    2005-03-03

    External cephalic version could be an alternative to either vaginal delivery or caesarean section in breech presentation at term. A systematic literature review about external cephalic version in breech presentation. The numbers of breech presentation delivered by caesarean section could probably be reduced in Norway by offering version, but this would not affect perinatal mortality.

  1. Conventional external beam radiotherapy for central nervous system malignancies

    International Nuclear Information System (INIS)

    Halperin, E.C.; Burger, P.C.

    1985-01-01

    Fractionated external beam photon radiotherapy is an important component of the clinical management of malignant disease of the central nervous system. The practicing neurologist or neurosurgeon frequently relies on the consultative and treatment skills of a radiotherapist. This article provides a review for the nonradiotherapist of the place of conventional external beam radiotherapy in neuro-oncology. 23 references

  2. External factors influencing the environmental performance of South African firms

    CSIR Research Space (South Africa)

    Peart, R

    2001-01-01

    Full Text Available This article reviews the external factors that influence environmental performance of companies in South Africa, drawing on international and local literature. After considering factors within the natural, social, economic and institutional...

  3. Environmental external effects from wind power based on the EU ExternE methodology

    DEFF Research Database (Denmark)

    Ibsen, Liselotte Schleisner; Nielsen, Per Sieverts

    1998-01-01

    of the Danish part of the project is to implement the framework for externality evaluation, for three different power plants located in Denmark. The paper will focus on the assessment of the impacts of the whole fuel cycles for wind, natural gas and biogas. Priority areas for environmental impact assessment......The European Commission has launched a major study project, ExternE, to develop a methodology to quantify externalities. A “National Implementation Phase”, was started under the Joule II programme with the purpose of implementing the ExternE methodology in all member states. The main objective...

  4. Bleeding and infection with external ventricular drainage: a systematic review in comparison with adjudicated adverse events in the ongoing Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR-III IHV) trial.

    Science.gov (United States)

    Dey, Mahua; Stadnik, Agnieszka; Riad, Fady; Zhang, Lingjiao; McBee, Nichol; Kase, Carlos; Carhuapoma, J Ricardo; Ram, Malathi; Lane, Karen; Ostapkovich, Noeleen; Aldrich, Francois; Aldrich, Charlene; Jallo, Jack; Butcher, Ken; Snider, Ryan; Hanley, Daniel; Ziai, Wendy; Awad, Issam A

    2015-03-01

    Retrospective series report varied rates of bleeding and infection with external ventricular drainage (EVD). There have been no prospective studies of these risks with systematic surveillance, threshold definitions, or independent adjudication. To analyze the rate of complications in the ongoing Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR III) trial, providing a comparison with a systematic review of complications of EVD in the literature. Patients were prospectively enrolled in the CLEAR III trial after placement of an EVD for obstructive intraventricular hemorrhage and randomized to receive recombinant tissue-type plasminogen activator or placebo. We counted any detected new hemorrhage (catheter tract hemorrhage or any other distant hemorrhage) on computed tomography scan within 30 days from the randomization. Meta-analysis of published series of EVD placement was compiled with STATA software. Growing or unstable hemorrhage was reported as a cause of exclusion from the trial in 74 of 5707 cases (1.3%) screened for CLEAR III. The first 250 patients enrolled have completed adjudication of adverse events. Forty-two subjects (16.8%) experienced ≥1 new bleeds or expansions, and 6 of 250 subjects (2.4%) suffered symptomatic hemorrhages. Eleven cases (4.4%) had culture-proven bacterial meningitis or ventriculitis. Risks of bleeding and infection in the ongoing CLEAR III trial are comparable to those previously reported in EVD case series. In the present study, rates of new bleeds and bacterial meningitis/ventriculitis are very low despite multiple daily injections, blood in the ventricles, the use of thrombolysis in half the cases, and generalization to >60 trial sites.

  5. External corners as heat bridges

    Energy Technology Data Exchange (ETDEWEB)

    Berber, J.

    1984-08-01

    The maximum additional heat loss in vertical external corners depending on wall thickness is determined. In order to amire at a low k-value, a much smaller wall thickness is required in externally insulated walls than in monolithic constructions; the greater loss of heat bridge with external insulation stands in contrast to a higher loss in thick, monolithic walls. In relation to total losses, the additional losses through external corners are practically negligible.

  6. [External pancreatic fistulas management].

    Science.gov (United States)

    Stepan, E V; Ermolov, A S; Rogal', M L; Teterin, Yu S

    The main principles of treatment of external postoperative pancreatic fistulas are viewed in the article. Pancreatic trauma was the reason of pancreatic fistula in 38.7% of the cases, operations because of acute pancreatitis - in 25.8%, and pancreatic pseudocyst drainage - in 35.5%. 93 patients recovered after the treatment. Complex conservative treatment of EPF allowed to close fistulas in 74.2% of the patients with normal patency of the main pancreatic duct (MPD). The usage of octreotide 600-900 mcg daily for at least 5 days to decrease pancreatic secretion was an important part of the conservative treatment. Endoscopic papillotomy was performed in patients with major duodenal papilla obstruction and interruption of transporting of pancreatic secretion to duodenum. Stent of the main pancreatic duct was indicated in patients with extended pancreatic duct stenosis to normalize transport of pancreatic secretion to duodenum. Surgical formation of anastomosis between distal part of the main pancreatic duct and gastro-intestinal tract was carried out when it was impossible to fulfill endoscopic stenting of pancreatic duct either because of its interruption and diastasis between its ends, or in the cases of unsuccessful conservative treatment of external pancreatic fistula caused by drainage of pseudocyst.

  7. External Events PSA for the Paks NPP

    International Nuclear Information System (INIS)

    Bareith, Attila; Karsa, Zoltan; Siklossy, Tamas; Vida, Zoltan

    2014-01-01

    Initially, probabilistic safety assessment of external events was limited to the analysis of earthquakes for the Paks Nuclear Power Plant in Hungary. The level 1 seismic PSA was completed in 2002 showing a significant contribution of seismic failures to core damage risk. Although other external events of natural origin had previously been screened out from detailed plant PSA mostly on the basis of event frequencies, a review of recent experience on extreme weather phenomena made during the periodic safety review of the plant led to the initiation of PSA for external events other than earthquakes in 2009. In the meantime, the accident of the Fukushima Dai-ichi Nuclear Power Plant confirmed further the importance of such an analysis. The external event PSA for the Paks plant followed the commonly known steps: selection and screening of external hazards, hazard assessment for screened-in external events, analysis of plant response and fragility, PSA model development, and risk quantification and interpretation of results. As a result of event selection and screening the following weather related external hazards were subject to detailed analysis: extreme wind, extreme rainfall (precipitation), extreme snow, extremely high and extremely low temperatures, lightning, frost and ice formation. The analysis proved to be a significant challenge due to scarcity of data, lack of knowledge, as well as limitations of existing PSA methodologies. This paper presents an overview of the external events PSA performed for the Paks NPP. Important methodological aspects are summarised. Key analysis findings and unresolved issues that need further elaboration are highlighted. Development of external events PSA for the Paks NPP was completed by the end of 2012. The analysis followed the commonly known steps: selection and screening of external hazards, hazard assessment for screened-in external events, analysis of plant response and fragility, PSA model development, and risk

  8. Protecting mobile agents from external replay attacks

    OpenAIRE

    Garrigues Olivella, Carles; Migas, Nikos; Buchanan, William; Robles, Sergi; Borrell Viader, Joan

    2014-01-01

    Peer-reviewed This paper presents a protocol for the protection of mobile agents against external replay attacks. This kind of attacks are performed by malicious platforms when dispatching an agent multiple times to a remote host, thus making it reexecute part of its itinerary. Current proposals aiming to address this problem are based on storing agent identifiers, or trip markers, inside agent platforms, so that future reexecutions can be detected and prevented. The problem of these solut...

  9. Hanford External Dosimetry Program

    International Nuclear Information System (INIS)

    Fix, J.J.

    1990-10-01

    This document describes the Hanford External Dosimetry Program as it is administered by Pacific Northwest Laboratory (PNL) in support of the US Department of Energy (DOE) and its Hanford contractors. Program services include administrating the Hanford personnel dosimeter processing program and ensuring that the related dosimeter data accurately reflect occupational dose received by Hanford personnel or visitors. Specific chapters of this report deal with the following subjects: personnel dosimetry organizations at Hanford and the associated DOE and contractor exposure guidelines; types, characteristics, and procurement of personnel dosimeters used at Hanford; personnel dosimeter identification, acceptance testing, accountability, and exchange; dosimeter processing and data recording practices; standard sources, calibration factors, and calibration processes (including algorithms) used for calibrating Hanford personnel dosimeters; system operating parameters required for assurance of dosimeter processing quality control; special dose evaluation methods applied for individuals under abnormal circumstances (i.e., lost results, etc.); and methods for evaluating personnel doses from nuclear accidents. 1 ref., 14 figs., 5 tabs

  10. Bevalac external beamline optics

    Energy Technology Data Exchange (ETDEWEB)

    Kalnins, J.G.; Krebs, G.F.; Tekawa, M.M.; Alonso, J.R.

    1987-04-01

    This handbook is intended as an aid for tuning the external particle beam (EPB) lines at the Lawrence Berkeley Laboratory's Bevalac. The information contained within will be useful to the Bevalac's Main Control Room and experimenters alike. First, some general information is given concerning the EPB lines and beam optics. Next, each beam line is described in detail: schematics of the beam line components are shown, all the variables required to run a beam transport program are presented, beam envelopes are given with wire chamber pictures and magnet currents, focal points and magnifications. Some preliminary scaling factors are then presented which should aid in choosing a given EPB magnet's current for a given central Bevalac field. Finally, some tuning hints are suggested.

  11. Bevalac external beamline optics

    International Nuclear Information System (INIS)

    Kalnins, J.G.; Krebs, G.F.; Tekawa, M.M.; Alonso, J.R.

    1987-04-01

    This handbook is intended as an aid for tuning the external particle beam (EPB) lines at the Lawrence Berkeley Laboratory's Bevalac. The information contained within will be useful to the Bevalac's Main Control Room and experimenters alike. First, some general information is given concerning the EPB lines and beam optics. Next, each beam line is described in detail: schematics of the beam line components are shown, all the variables required to run a beam transport program are presented, beam envelopes are given with wire chamber pictures and magnet currents, focal points and magnifications. Some preliminary scaling factors are then presented which should aid in choosing a given EPB magnet's current for a given central Bevalac field. Finally, some tuning hints are suggested

  12. Accessing external innovation in drug discovery and development.

    Science.gov (United States)

    Tufféry, Pierre

    2015-06-01

    A decline in the productivity of the pharmaceutical industry research and development (R&D) pipeline has highlighted the need to reconsider the classical strategies of drug discovery and development, which are based on internal resources, and to identify new means to improve the drug discovery process. Accepting that the combination of internal and external ideas can improve innovation, ways to access external innovation, that is, opening projects to external contributions, have recently been sought. In this review, the authors look at a number of external innovation opportunities. These include increased interactions with academia via academic centers of excellence/innovation centers, better communication on projects using crowdsourcing or social media and new models centered on external providers such as built-to-buy startups or virtual pharmaceutical companies. The buzz for accessing external innovation relies on the pharmaceutical industry's major challenge to improve R&D productivity, a conjuncture favorable to increase interactions with academia and new business models supporting access to external innovation. So far, access to external innovation has mostly been considered during early stages of drug development, and there is room for enhancement. First outcomes suggest that external innovation should become part of drug development in the long term. However, the balance between internal and external developments in drug discovery can vary largely depending on the company strategies.

  13. Externalities of fuel cycles 'ExternE' project. Economic valuation. Economical valuation: An impact pathway approach

    International Nuclear Information System (INIS)

    Markandya, A.

    1994-01-01

    European literature as was feasible has been carried out, such a survey is certain to fall short of reviewing the full literature simply because the larger part of it is North American. The latter was being reviewed separately by the US team. However, in making recommendations as to what valuation methods or studies to use, the report draws on the substantial US experience. The whole issue of when a methodology or a particular study can be transferred from one context to another has never been fully addressed. This report makes some suggestions as to when this is may be appropriate although it is recognized that this is by no means a definitive discussion of that issue. Certainly, the fact that the fuel cycle analysis here is location-specific, rather than 'generic', in the sense of providing broad average costs of impacts caused by the use of certain fuels, makes the transferability of estimates more difficult. The report is structured as follows. Part I begins with a discussion of the nature of externalities and a more precise definition of what is being measured. Of particular importance in this context is the extent to which an environmental impact is or is not an 'externality'. Without going into the more complex aspects of the economic theory, the report offers some advice on when the issue is relevant and what criteria might be used to assess whether or not a particular environmental impact really is an externality. The remainder of Part I then deals with a number of general issues that are of practical importance in the context of valuing specific impacts. These are: the question of transferability discussed above; the time period or timescale over which the valuation is to take place; the treatment of uncertainty; the discounting of future costs; and the finally the issue of exactly what is being assumed constant when a particular valuation is being carried out. This is of special significance in the context of the valuation being undertaken here. Part II of the

  14. External radiation carcinogenesis

    International Nuclear Information System (INIS)

    Fry, R.J.M.; Storer, J.B.

    1987-01-01

    There have been many reviews of the subject of radiation carcinogenesis in general and of specific radiation-induced cancers. The aim of this article is not to give an exhaustive, and perhaps exhausting, review of all that has been published since the thorough treatise of Walburg in volume 4 of this series but rather to concentrate on the questions that still remain of importance and recent contributions to the answers. In the years since 1974 a vast amount of information has been reported, and the authors assess what gain there has been in knowledge. For example, it is in the 13 years since the last review that the great majority of data for the carcinogenic effects of neutrons has appeared. It is over 50 years since the discovery of the neutron, and yet knowledge of the carcinogenic effects of neutrons is far from adequate

  15. The ExternE project: methodology, objectives and limitations

    International Nuclear Information System (INIS)

    Rabl, A.; Spadaro, J.V.

    2002-01-01

    This paper presents a summary of recent studies on external costs of energy systems, in particular the ExternE (External Costs of Energy) Project of the European Commission. To evaluate the impact and damage cost of a pollutant, one needs to carry out an impact pathway analysis; this involves the calculation of increased pollutant concentrations in all affected regions due to an incremental emission (e.g. μg/m 3 of particles, using models of atmospheric dispersion and chemistry), followed by the calculation of physical impacts (e.g. number of cases of asthma due to these particles, using a dose-response function). The entire so-called fuel chain (or fuel cycle) is evaluated and compared on the basis of delivered end use energy. Even though the uncertainties are large, the results provide substantial evidence that the classical air pollutants (particles, NO x and SO x ) from the combustion of fossil fuels impose a heavy toll, in addition to the cost of global warming. The external costs are especially large for coal; even for 'good current technology' they may be comparable to the price of electricity. For natural gas the external costs are about a third to a half of coal. The external costs of nuclear are small compared to the price of electricity (at most a few %), and so are the external costs of most renewable energy systems. (authors)

  16. Reviews

    Science.gov (United States)

    2002-11-01

    CD-ROM REVIEW (551) Essential Physics BOOK REVIEWS (551) Collins Advanced Science: Physics, 2nd edition Quarks, Leptons and the Big Bang, 2nd edition Do Brilliantly: A2 Physics IGCSE Physics Geophysics in the UK Synoptic Skills in Advanced Physics Flash! The hunt for the biggest explosions in the universe Materials Maths for Advanced Physics

  17. IRIS Toxicological Review of Thallium and Compounds (External Review Draft)

    Science.gov (United States)

    Thallium compounds are used in the semiconductor industry, the manufacture of optic lenses and low-melting glass, low-temperature thermometers, alloys, electronic devices, mercury lamps, fireworks, and imitation germs, and clinically as an imaging agent in the diagnosis of certai...

  18. IRIS Toxicological Review of Ammonia (Revised External Review Draft)

    Science.gov (United States)

    In August 2013, EPA submitted a revised draft IRIS assessment of ammonia to the agency's Science Advisory Board (SAB) and posted this draft on the IRIS website. EPA had previously released a draft of the assessment for public comment, held a public meeting about the draft, and ...

  19. Retrofitting Systems for External Walls

    DEFF Research Database (Denmark)

    Rose, Jørgen

    1997-01-01

    In this report, 9 different external and internal retrofitting systems are analyzed using numerical calculations. The analysis focuses on the thermal bridge effects in the different systems, and on this basis it is discussed whether internal or external retrofitting has the most advantages...

  20. Performance Targets and External Benchmarking

    DEFF Research Database (Denmark)

    Friis, Ivar; Hansen, Allan; Vámosi, Tamás S.

    Research on relative performance measures, transfer pricing, beyond budgeting initiatives, target costing, piece rates systems and value based management has for decades underlined the importance of external benchmarking in performance management. Research conceptualises external benchmarking...... as a market mechanism that can be brought inside the firm to provide incentives for continuous improvement and the development of competitive advances. However, whereas extant research primarily has focused on the importance and effects of using external benchmarks, less attention has been directed towards...... the conditions upon which the market mechanism is performing within organizations. This paper aims to contribute to research by providing more insight to the conditions for the use of external benchmarking as an element in performance management in organizations. Our study explores a particular type of external...

  1. Malignant external otitis: CT evaluation

    International Nuclear Information System (INIS)

    Curtin, H.D.; Wolfe, P.; May, M.

    1982-01-01

    Malignant external otitis is an aggressive infection caused by Pseudomonas aeruginosa that most often occurs in elderly diabetics. Malignant external otitis often spreads inferiorly from the external canal to involve the subtemporal area and progresses medially towards the petrous apex leading to multiple cranial nerve palsies. The computed tomographic (CT) findings in malignant external otitis include obliteration of the normal fat planes in the subtemporal area as well as patchy destruction of the bony cortex of the mastoid. The point of exit of the various cranial nerves can be identified on CT scans, and the extent of the inflammatory mass correlates well with the clinical findings. Four cases of malignant external otitis are presented. In each case CT provided a good demonstration of involvement of the soft tissues at the base of the skull

  2. The Estimation of Externalities Resulting from the Electricity Generation

    International Nuclear Information System (INIS)

    Jeong, Jong Tae; Ha, Jae Joo

    2003-03-01

    The methodology, program, and the representative results for the estimation of externalities was reviewed. The review of them are based on the ExternE Project which is a representative research project for the estimation of externalities resulting from the various energy generating systems. The results for the study will be used as basic data for the comparative study on the integrated risk estimation for various energy generating systems including nuclear power plants. Also, these results will be used as comparative data in the establishment of a integrated comparative risk assessment tool and in the comparative study of the impacts resulting from the various electricity generating systems. These studies make it possible to compare the environmental impacts of nuclear power generation and other electricity generation systems. Therefore, this will of use in the enhancement of public acceptance of nuclear power generation

  3. The Estimation of Externalities Resulting from the Electricity Generation

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Jong Tae; Ha, Jae Joo

    2003-03-15

    The methodology, program, and the representative results for the estimation of externalities was reviewed. The review of them are based on the ExternE Project which is a representative research project for the estimation of externalities resulting from the various energy generating systems. The results for the study will be used as basic data for the comparative study on the integrated risk estimation for various energy generating systems including nuclear power plants. Also, these results will be used as comparative data in the establishment of a integrated comparative risk assessment tool and in the comparative study of the impacts resulting from the various electricity generating systems. These studies make it possible to compare the environmental impacts of nuclear power generation and other electricity generation systems. Therefore, this will of use in the enhancement of public acceptance of nuclear power generation.

  4. Reviews.

    Science.gov (United States)

    Journal of Chemical Education, 1987

    1987-01-01

    Provides a review of both the Apple and IBM versions of ENZPACK, a software package which is designed to assist in the teaching of enzyme kinetics in courses where this topic is treated in some depth. (TW)

  5. Review

    Indian Academy of Sciences (India)

    2012-03-29

    Mar 29, 2012 ... The present review documents an overview of speciation mediated through behavioural ...... The Drosophila model (New York: Oxford University Press) .... second part of his big species book written from 1856–1858. (New ...

  6. External costs related to power production technologies. ExternE national implementation for Denmark

    International Nuclear Information System (INIS)

    Schleisner, L.; Sieverts Nielsen, P.

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results; to aggregate these site- and technology-specific results to more general figures. The current report covers the results of the national implementation for Denmark. Three different fuel cycles have been chosen as case studies. These are fuel cycles for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant based on biogas. The report covers all the details of the application of the methodology to these fuel cycles aggregation to a national level. (au) EU-JOULE 3. 59 tabs., 25 ills., 61 refs

  7. External costs related to power production technologies. ExternE national implementation for Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Schleisner, L; Sieverts Nielsen, P

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results; to aggregate these site- and technology-specific results to more general figures. The current report covers the results of the national implementation for Denmark. Three different fuel cycles have been chosen as case studies. These are fuel cycles for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant based on biogas. The report covers all the details of the application of the methodology to these fuel cycles aggregation to a national level. (au) EU-JOULE 3. 59 tabs., 25 ills., 61 refs.

  8. Analgesia/anesthesia for external cephalic version.

    Science.gov (United States)

    Weiniger, Carolyn F

    2013-06-01

    Professional society guidelines recommend that women with breech presentation be delivered surgically due to a higher incidence of fetal risks compared with vaginal delivery. An alternative is attempted external cephalic version, which if successful, enables attempted vaginal delivery. Attitudes towards external cephalic version (ECV) will be considered in this review, along with pain relief methods and their impact on ECV success rates. Articles suggest that ECV is infrequently offered, due to both physician and patient factors. Success of ECV is higher in multiparous women, complete breech, posterior placenta, or smaller fetus. Preterm ECV performance does not increase vaginal delivery rates. Neuraxial techniques (spinal or epidural) significantly increase ECV success rates, as do moxibustion and hypnosis. Four reviews summarized studies considering ECV and neuraxial techniques. These reviews suggest that neuraxial techniques using high (surgical) doses of local anesthetic are efficacious compared with control groups not using anesthesia, whereas techniques using low-doses are not. Low-dose versus high-dose neuraxial analgesia/anesthesia has not been directly compared in a single study. Based on currently available data, the rate of cephalic presentation is not increased using neuraxial techniques, but vaginal delivery rates are higher. ECV appears to be a low-risk procedure. The logistics of routine ECV and provision of optimal neuraxial techniques for successful ECV require additional research. Safety aspects of neuraxial anesthesia for ECV require further investigation.

  9. External meeting: Geneva University

    CERN Multimedia

    2006-01-01

    Université de Genève Ecole de physique 24 quai Ernest Ansermet 1211 Genève 4 Tél : + 41 22 379 63 83 (secrétariat) Tél : + 41 22 379 62 56 (réception) Fax: + 41 22 379 69 22 Lundi 20 novembre 2006 COLLOQUIUM 17:00 - Auditoire Stückelberg Electrical correlation measurements in quantum nano-structures Dr. Stefan Oberholzer / Basel University Measuring the current-voltage characteristics of small conductors is widely used to characterize their electronic transport properties. In addition to such time-averaged measurements, correlation measurements between temporal fluctuations (noise) around the time-averaged mean current provide us with very important supplementary information about electrical transport. In this talk, I review our experimental work on shot noise, noise which originates from the granularity of charge and the diffraction of the electronic wave-function, and especially address the fundamental relation between electronic scattering experiments and the statistical properties of indist...

  10. External effects in Swiss hydropower

    International Nuclear Information System (INIS)

    Hauenstein, W.; Bonvin, J.; Vouillamoz, J.

    1999-01-01

    The article discusses the external costs and benefits of hydropower that are not internalised in normal book-keeping. Several negative and positive effects are discussed. The results of a study that addressed the difficult task of quantifying these external effects are presented. An assessment of the results gained shows that difficulties are to be met regarding system limits, methods of expressing the effects in monetary terms and ethical factors. The report also examines the consideration of external effects as a correction factor for falsified market prices for electricity

  11. Otite externa necrotizante com paralisia facial periférica bilateral: relato de caso e revisão da literatura Necrotizing external otitis with periferic bilateral facial palsy: case report and literature review

    Directory of Open Access Journals (Sweden)

    Antonio Antunes

    2004-01-01

    Full Text Available A otite externa necrotizante (OEN, conhecida no passado como otite externa maligna, é uma infecção potencialmente letal que começa usualmente no conduto auditivo externo e se estende à base do crânio ocorrendo, principalmente, em pacientes diabéticos idosos e que a despeito de antibioticoterapia prolongada está associada à morbidade elevada e mortalidade significante. Os autores apresentam o caso de um paciente adulto, diabético, com OEN e paralisia facial periférica bilateral que evoluiu com cura da infecção, porém sem melhora da paralisia.Necrotizing external otitis (NEO, known in the past as malignant external otitis, is a potencial letal infection which begins usually in the external ear canal and spreads to the base of the skull. It occurs mainly in diabetic elderly patients who despite prolonged antibioticotherapy is associated to high morbidity and significant mortality. The authors present a case of an adult diabetic patient who developed NOE associated with bilateral periferic facial palsy evoluting with cure of the infection but without facial improvement.

  12. Control of external radiation exposure

    International Nuclear Information System (INIS)

    Abd Nasir Ibrahim; Azali Muhammad; Ab Razak Hamzah; Abd Aziz Mohamed; Mohammad Pauzi Ismail

    2004-01-01

    The following subjects are discussed - Control of external radiation exposure: working time, working distance, shielding: Total Linear Attenuation Coefficient, Half-Value Layer (HVL), Tenth-Value Layer (TVL); Build-up Factor

  13. External costs related to power production technologies. ExternE national implementation for Denmark

    International Nuclear Information System (INIS)

    Schleisner, L.; Sieverts Nielsen, P.

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results, to aggregate these site- and technology-specific results to more general figures. The current report covers the detailed information concerning the ExternE methodology. Importance is attached to the computer system used in the project and the assessment of air pollution effects on health, materials and ecological effects. Also the assessment of global warming damages are described. Finally the report covers the detailed information concerning the national implementation for Denmark for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant base on biogas. (au) EU-JOULE 3. 79 tabs., 11 ills., 201 refs

  14. External costs related to power production technologies. ExternE national implementation for Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Schleisner, L; Sieverts Nielsen, P [eds.

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results, to aggregate these site- and technology-specific results to more general figures. The current report covers the detailed information concerning the ExternE methodology. Importance is attached to the computer system used in the project and the assessment of air pollution effects on health, materials and ecological effects. Also the assessment of global warming damages are described. Finally the report covers the detailed information concerning the national implementation for Denmark for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant base on biogas. (au) EU-JOULE 3. 79 tabs., 11 ills., 201 refs.

  15. Externalities of energy. Swedish implementation of the ExternE methodology

    International Nuclear Information System (INIS)

    Nilsson, Maans; Gullberg, M.

    1998-01-01

    The growing interest for developing economic instruments for efficient environmental policies has opened up a large area of multi-disciplinary research. ExternE is an example of this research, combining disciplines such as engineering, ecology, immunology and economics expertise to create new knowledge about how environmental pressures from energy production affect our nature and society. The ExternE Project aims to identify and, as far as possible quantify the externalities of energy production in Europe. The Stockholm Environment Institute has carried out a preliminary aggregation: -Coal Fuel Cycle: centred around Vaesteraas Kraftvaermeverk, Vaesteraas. This is the largest co-generation plant in Sweden, with four blocks and a maximum co-generation output of 520 MW electricity and 950 MW heat. The analysis is carried out on boiler B4. -Biomass Fuel Cycle: centred around Haendeloeverket, Norrkoeping. This plant predominately burns forestry residues, but a variety of fuels are combusted. Haendeloeverket has an installed capacity of 100 MW electricity and 375 MW heat, in a total of three boilers and two back-pressure turbines. The analysis is carried out on boiler P13. -Hydro Fuel Cycle: Klippens Kraftstation, Storuman. Built in 1990-1994, it is the youngest hydro power station in Sweden. It has been designed and built with significant efforts to account for and protect environmental values. Installed capacity is 28 MW. The environmental impact assessment from the construction of this plant is carried out, but the evaluation is still not finalized. The preliminary aggregation aimed to test whether ExternE results could be used to make estimates for the entire Swedish electricity production system. Hence, national results as well as results from other partner countries in ExternE has been applied

  16. Environmental externalities and alternative energy choices

    International Nuclear Information System (INIS)

    Williams, L.J.

    1993-01-01

    This paper will introduce and explain the economic concept of an open-quotes externalityclose quotes and how it applies to environmental issues. The theory was developed by economists more than a half century ago. Much of the current interest in the idea is aimed at its application to environmental issues in the regulated electric and gas utility industries. A good deal of this current interest began with the publication of the Pace University report on the Environmental Costs of Electricity. The report is widely cited but, unfortunately, seriously flawed. Two important examples of this will be shown later in this paper. The widespread interest in the application of the environmental externality concept apparently arose out of the desire of regulators and others to open-quotes level the playing fieldclose quotes for Demand Side Management (DSM) activities and renewables. The rapid growth of DSM over the past 10 to 15 years has occurred without any boost from externalities. By including the complete private and social costs of traditional electric generating technologies, it is thought that DSM and renewables will get an additional boost. Although current activity aims at the application of the environmental externality concept to the regulated utilities sector, it clearly has potential for much wider application. This issue will also be examined. The current status of various regulatory actions at the state level will be reviewed

  17. Monetization of Environmental Externalities (Emissions from Bioenergy

    Directory of Open Access Journals (Sweden)

    Isabelle BROSE

    2008-01-01

    Full Text Available Bioenergy from agriculture is today in the heart of sustainabledevelopment, integrating its key components: environment and climate change,energy economics and energy supply, agriculture, rural and social development.Each bioenergy production route presents externalities that must be assessed inorder to compare one bioenergy route to another (bioenergy route. The lack ofprimary and reliable data on externalities is, nevertheless, an important nontechnologicalbarrier to the implementation of the best (bioenergy routes. In thisarticle, we want to monetize one environmental externality from bioenergy:emissions (GHG: CO2, CH4, N2O, O3; CO, NOx, SO2, metal, and PM. We have tomonetize emissions on the basis of their effects on health, global warming, and soiland water quality. Emissions will be quantified through Life Cycle Analysis (LCAand ECOINVENT database. Impacts on health will be monetized on the basis ofmortality (number of life expectancy years lost multiplied by Value Of Life Year(VOLY and morbidity (number of ill persons multiplied by Cost Of Illness(COI. Impacts on global warming will be monetized by Benefits Transfers fromthe Stern Review and its critics. Finally, impacts on soil and water quality will bemonetized by Averting Behaviour or Defensive Expenses methods. Monetizationresults will be gathered, weighted, and incorporated in states and firms’ decisionmakingtools. They would enhance capacity of policy makers and managers tochose the best (bioenergy routes.

  18. Urban Sprawl and Transportation Externalities

    OpenAIRE

    Holcombe, Randall G.; Williams, DeEdgra W.

    2010-01-01

    One argument in support of minimizing urban sprawl is that sprawl creates transportation externalities. A problem with empirically examining the relationship between sprawl and transportation externalities is that sprawl is a difficult concept to quantify. This paper uses a measure of sprawl designed by Ewing, Pendall, and Chen (2002) to examine the relationship between sprawl and commute times, automobile ownership, miles driven, fatal auto accidents, air pollution, and highway expenditures....

  19. Conceptual challenges for internalising externalities

    DEFF Research Database (Denmark)

    Miguel, Brandão; Weidema, Bo Pedersen

    2013-01-01

    We analyse a number of different externalities to identify conceptual challenges for the practical implementation of their internalisation. Three issues were identified: i) The balance between compensation and technology change and the respective effects on the nominal and real GDP; ii...... geographical and especially temporal distance between the benefitting actor and the victim of the external cost, the involvement of a non-governmental intermediate actor becomes increasingly necessary to provide the short-term capital required to ensure a successful implementation....

  20. Parallel External Memory Graph Algorithms

    DEFF Research Database (Denmark)

    Arge, Lars Allan; Goodrich, Michael T.; Sitchinava, Nodari

    2010-01-01

    In this paper, we study parallel I/O efficient graph algorithms in the Parallel External Memory (PEM) model, one o f the private-cache chip multiprocessor (CMP) models. We study the fundamental problem of list ranking which leads to efficient solutions to problems on trees, such as computing lowest...... an optimal speedup of ¿(P) in parallel I/O complexity and parallel computation time, compared to the single-processor external memory counterparts....

  1. Internal hiring or external recruitment?

    OpenAIRE

    DeVaro, Jed

    2016-01-01

    Hiring is one of a firm’s most important decisions. When an employer fills a vacancy with one of its own workers (through promotion or lateral transfer), it forgoes the opportunity to fill the position with a new hire from outside the firm. Although both internal and external hiring methods are used, firms frequently have a bias favoring insiders. Internal and external hires differ in observable characteristics (such as skill levels), as do the employers making each type of hiring decision. U...

  2. Review

    DEFF Research Database (Denmark)

    Van Den Hazel, H B; Kielland-Brandt, Morten; Winther, Jakob R.

    1996-01-01

    The yeast vacuole, which is equivalent to the lysosome of higher eukaryotes, is one of the best characterized degradative organelles. This review describes the biosynthesis and function of yeast vacuolar proteases. Most of these enzymes are delivered to the vacuole via the early compartments...

  3. Reviews

    NARCIS (Netherlands)

    Adema, Frits

    1995-01-01

    This is the second volume of a revision of Tabernaemontana (Apocynaceae). The volume covers the New World species (44) and the genus Stemmadenia (10 species). This part of the revision of Tabernaemontana comes up to the high standards set in the first volume [see the review by Leenhouts, Blumea 38

  4. Reviews.

    Science.gov (United States)

    Science Teacher, 1989

    1989-01-01

    Reviews a software planetarium package called "Sky Travel." Includes two audiovisuals: "Conquest of Space" and "Windows on Science: Earth Science"; and four books: "Small Energy Sources: Choices that Work,""Stonehenge Complete,""Uneasy Careers and Intimate Lives: Women in Science…

  5. REVIEW

    African Journals Online (AJOL)

    2012-03-01

    Mar 1, 2012 ... narrowing the gap between recommended treatment protocols in ... for pregnant women is complicated by the need to take into account the health and safety of both the ... meta-analysis as at July 2011 (which reviews the APR and other ... 0.82 - 3.18) and relative risk of birth defects in EFV-containing ART.

  6. Review

    Indian Academy of Sciences (India)

    Review. J. Astrophys. Astr., Vol. 36, No. 4, December 2015, pp. 623–634 ..... 4000 K ≤ T ≤ 10000 K. The processes (1b) are characterized in this paper via ..... Mihajlov, A. A., Sreckovic, V. A., Ignjatovic, L. M., Klyucharev, A. N. 2012, J. Cluster.

  7. Review

    NARCIS (Netherlands)

    Kalkman, C.; Adema, F.

    1998-01-01

    This book intends (according to the preface) to afford at once a review, a general outline of what has been accomplished, and a set of signposts for the future. It attempts to do so in three sections on Origin and Diversification of Primitive Land Plants (4 papers), Origin and Diversification of

  8. Review

    NARCIS (Netherlands)

    Wilde, de W.J.J.O.

    1994-01-01

    This review marks the appearance of Volume II, after the publication of Volume I, Pteridophytes and Gymnosperms, in 1990; several more volumes are expected in the future before completion of the Vascular plants as a whole. The present volume contains 73 families out of some 250-500 families which

  9. The Role of External Environment in Upper Echelons Theory

    DEFF Research Database (Denmark)

    Yamak, Sibel; Nielsen, Sabina; Escribá-Esteve, Alejandro

    2014-01-01

    and industrial organization theories, a cross-level conceptual model outlining the direct, mediating, and moderating effects of the external environment on upper echelons is developed. This review distinguishes between industry and institutional levels of analysis and three types of environmental characteristics......Upper echelons research has largely focused on the antecedents and consequences of top management teams (TMTs) from the team and firm levels of analysis. This paper reviews empirical research on TMTs with a specific emphasis on the role of the external environment. Applying institutional...

  10. Approaches in estimation of external cost for fuel cycles in the ExternE project

    International Nuclear Information System (INIS)

    Afanas'ev, A.A.; Maksimenko, B.N.

    1998-01-01

    The purposes, content and main results of studies realized within the frameworks of the International Project ExternE which is the first comprehensive attempt to develop general approach to estimation of external cost for different fuel cycles based on utilization of nuclear and fossil fuels, as well as on renewable power sources are discussed. The external cost of a fuel cycle is treated as social and environmental expenditures which are not taken into account by energy producers and consumers, i.e. these are expenditures not included into commercial cost nowadays. The conclusion on applicability of the approach suggested for estimation of population health hazards and environmental impacts connected with electric power generation growth (expressed in money or some other form) is made

  11. Reviews

    Directory of Open Access Journals (Sweden)

    Philip Barker

    1998-12-01

    Full Text Available There were two copy-editing blunders in Clive Betts's review, in ALT-J 5 (3, of Shirley Fletcher's Designing Competence-Based Training, one in paragraph 2 line 1, the other in paragraph 3 line 8. The errors (the result of the Editor, Gabriel Jacobs, trying to perform a final proof of the journal at lightning speed in order to meet the printing deadline, and not of any mistake on the part of either Philip Barker or the University of Wales Press hardly affected meaning, but the fact that they appeared in a review of a book on competence makes the embarrassment all the more telling. The Editor apologizes, and thanks eagle-eyed readers. He has decided to read the book in the hope that such errors will not recur.

  12. Reviews

    Directory of Open Access Journals (Sweden)

    Wilma D'Ambrosio

    2013-12-01

    Full Text Available In the wake of the great interest raised by Maurizio Gabrieli’s review of the book Musical Networks. Parallel Distributed Perception and Performance (various authors; edited by Niall Griffith and Peter M. Todd, MA: MIT Press, Cambridge, 1999 which appeared in our last issue of Analitica, the present review section no longer follows the format used up to now but offers a survey of texts dedicated to the relationship between music analysis and technology. This decision was also made as a result of the request for more information on the subject by many of our readers. In coming issues we plan to extend this bibliography and comment on at least some of the most interesting texts published in recent years, among which we would immediately like to draw attention to the important work by Baroni, Dalmonte and Jacoboni published in 1999 (Le regole della musica. Indagine sui meccanismi della comunicazione, Torino, I Manuali EDT/SIdM, 1999.

  13. A study of the external cooling capability for the prevention of reactor vessel failure

    Energy Technology Data Exchange (ETDEWEB)

    Chang, S H; Baek, W P; Moon, S K; Yang, S H; Kim, S H [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

    1995-07-15

    This study (a 3-year program) aims to perform a comprehensive assessment of the feasibility of external vessel flooding with respect to advanced pressurized water reactor plants to be built in Korea. During the second year, appropriate correlations have been chosen to describe the phenomena resulted from the external flooding on the basis of review works. Also performed is to develop the computer program using the chosen correlations and to accomplish the thermal analysis for assessment of the cooling capability of external flooding. Accomplished works for second year are as follows. Review of analytical and experimental works related to the external flooding are performed, appropriate correlations are chosen to describe the phenomena resulted from the external flooding on the basis of first and second year review works. A computer program is also developed to predict the temperature distribution of reactor vessel lower head. Thermal analyses are performed to judge the feasibility of external flooding using developed computer program.

  14. Reconceptualising the external validity of discrete choice experiments.

    Science.gov (United States)

    Lancsar, Emily; Swait, Joffre

    2014-10-01

    External validity is a crucial but under-researched topic when considering using discrete choice experiment (DCE) results to inform decision making in clinical, commercial or policy contexts. We present the theory and tests traditionally used to explore external validity that focus on a comparison of final outcomes and review how this traditional definition has been empirically tested in health economics and other sectors (such as transport, environment and marketing) in which DCE methods are applied. While an important component, we argue that the investigation of external validity should be much broader than a comparison of final outcomes. In doing so, we introduce a new and more comprehensive conceptualisation of external validity, closely linked to process validity, that moves us from the simple characterisation of a model as being or not being externally valid on the basis of predictive performance, to the concept that external validity should be an objective pursued from the initial conceptualisation and design of any DCE. We discuss how such a broader definition of external validity can be fruitfully used and suggest innovative ways in which it can be explored in practice.

  15. The effect of childhood malnutrition on externalizing behavior.

    Science.gov (United States)

    Liu, Jianghong; Raine, Adrian

    2006-10-01

    Childhood externalizing behavior (aggression, hyperactivity, and conduct disorder) has been increasingly viewed as a public health problem because of its etiology and outcome. The association between malnutrition and externalizing behavior has begun to receive attention. This review summarizes recent empirical findings on malnutrition as a risk factor for the development of externalizing behavior, with an emphasis on micronutrient deficiency, and explores brain dysfunction as a possible mechanism. Externalizing behavior is associated with both macromalnutrition (e.g. protein) and micromalnutrition (e.g. iron and zinc). Both prenatal and postnatal malnutrition is implicated. The long-term effects of malnutrition on behavior could be reversible. The effects of docosahexaenoic acid/omega-3 long-chain essential fatty acid on externalizing behavior are more mixed. From animal and human findings, it is hypothesized that malnutrition impairs neurocognitive functioning by reducing neurons, alternating neurotransmitter functioning, and increasing neurotoxicity, and that such neurocognitive impairments predispose to externalizing behavior. Different lines of evidence support the view that poor nutrition contributes to the development of child behavior problems. More randomized, controlled trials that manipulate nutritional intake and evaluate behavior in children are needed to evaluate the etiological role of nutrition in externalizing behavior in order to inform intervention and prevention efforts.

  16. Evolution of external genitalia: insights from reptilian development.

    Science.gov (United States)

    Gredler, Marissa L; Larkins, Christine E; Leal, Francisca; Lewis, A Kelsey; Herrera, Ana M; Perriton, Claire L; Sanger, Thomas J; Cohn, Martin J

    2014-01-01

    External genitalia are found in each of the major clades of amniotes. The phallus is an intromittent organ that functions to deliver sperm into the female reproductive tract for internal fertilization. The cellular and molecular genetic mechanisms of external genital development have begun to be elucidated from studies of the mouse genital tubercle, an embryonic appendage adjacent to the cloaca that is the precursor of the penis and clitoris. Progress in this area has improved our understanding of genitourinary malformations, which are among the most common birth defects in humans, and created new opportunities for comparative studies of other taxa. External genitalia evolve rapidly, which has led to a striking diversity of anatomical forms. Within the past year, studies of external genital development in non-mammalian amniotes, including birds, lizards, snakes, alligators, and turtles, have begun to shed light on the molecular and morphogenetic mechanisms underlying the diversification of phallus morphology. Here, we review recent progress in the comparative developmental biology of external genitalia and discuss the implications of this work for understanding external genital evolution. We address the question of the deep homology (shared common ancestry) of genital structures and of developmental mechanisms, and identify new areas of investigation that can be pursued by taking a comparative approach to studying development of the external genitalia. We propose an evolutionary interpretation of hypospadias, a congenital malformation of the urethra, and discuss how investigations of non-mammalian species can provide novel perspectives on human pathologies.

  17. External dosimetry sources and shielding

    International Nuclear Information System (INIS)

    Calisto, Washington

    1994-01-01

    A definition of external dosimetry r external sources dosimetry,physical and mathematical treatment of the interaction of gamma radiation with a minimal area in that direction. Concept of attenuation coefficient, cumulated effect by polyenergetic sources, exposition rate, units, cumulated dose,shielding, foton shielding, depth calculation, materials used for shielding.Beta shielding, consideration of range and maximum β energy , low stopping radiation by use of low Z shielding. Tables for β energy of β emitters, I (tau) factor, energy-range curves for β emitters in aqueous media, gamma attenuation factors for U, W and Pb. Y factor for bone tissue,muscle and air, build-up factors

  18. Environmental externalities related to power production on biogas and natural gas based on the EU ExternE methodology

    DEFF Research Database (Denmark)

    Nielsen, Per Sieverts; Ibsen, Liselotte Schleisner

    1998-01-01

    This paper assesses the environmental impacts and external costs from selected electricity generation systems in Denmark. The assessment is carried out as part of the ExternE National Implementation, which is the second phase of the ExternE project and involves case studies from all Western...... European countries. The project use a “bottom-up” methodology to evaluate the external costs associated with a wide range of different fuel cycles. The project has identified priority impacts, where most are impacts from air emissions. Externalities due to atmospheric emissions are calculated through...

  19. External cephalic version-related risks: a meta-analysis

    NARCIS (Netherlands)

    Grootscholten, K.; Kok, M.; Oei, S.G.; Mol, B.W.J.; Post, van der J.A.

    2008-01-01

    OBJECTIVE: To systematically review the literature on external cephalic version–related complications and to assess if the outcome of a version attempt is related to complications. DATA SOURCES: In March 2007 we searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials.

  20. External Cephalic Version-Related Risks A Meta-analysis

    NARCIS (Netherlands)

    Grootscholten, Kim; Kok, Marjolein; Oei, S. Guid; Mol, Ben W. J.; van der Post, Joris A.

    2008-01-01

    OBJECTIVE: To systematically review the literature on external cephalic version-related complications and to assess if the outcome of a version attempt is related to complications. DATA SOURCES: In March 2007 we searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials.

  1. Ability performance of older workers - Internal and external influencing factors

    NARCIS (Netherlands)

    Dittmann-Kohli, F.; Heijden, B.I.J.M. van der

    1996-01-01

    Internal and external factors affecting ability and performance of older employees are being analyzed in a short literature review. Internal factors like physical capacity, sensory capacity, cognitive abilities and general health are reduced with ageing; their effect on performance, however, depends

  2. Quantization of fermions in external soliton fields and index calculation

    International Nuclear Information System (INIS)

    Grosse, H.

    1986-01-01

    We review recent results on the quantization of fermions in external fields, discuss equivalent and inequivalent representations of the canonical anticommutation relations, indicate how the requirement of implementability of gauge transformations leads to quantization conditions, determine the algebra of charges, identify the Schwinger term and remark finally how one may calculate a ground state charge. (Author)

  3. 40 CFR 1.37 - Office of External Affairs.

    Science.gov (United States)

    2010-07-01

    ... program direction and professional review of the performance of public affairs functions in the Regional... result in contracts in the area of public information and community relations. It develops proposals and... Administrator for External Affairs and supervises all the functions of the Office. The Director acts as national...

  4. PHOSPHORUS SORPTION ISOTHERMS AND EXTERNAL ...

    African Journals Online (AJOL)

    ACSS

    Zhang et al., 2005). For instance, in strongly acidic soils with pH<5.5 and high P sorbing soils, application of rock phosphate is more effective and cheaper than using TSP (Bationo et al., 2011). Moreover, it enables determination of the external P.

  5. Hydropower externalities: a meta analysis

    NARCIS (Netherlands)

    Mattmann, M.; Logar, I.; Brouwer, R.

    2016-01-01

    This paper presents a meta-analysis of existing research related to the economic valuation of the external effects of hydropower. A database consisting of 81 observations derived from 29 studies valuing the non-market impacts of hydropower electricity generation is constructed with the main aim to

  6. Matching Games with Additive Externalities

    DEFF Research Database (Denmark)

    Branzei, Simina; Michalak, Tomasz; Rahwan, Talal

    2012-01-01

    Two-sided matchings are an important theoretical tool used to model markets and social interactions. In many real life problems the utility of an agent is influenced not only by their own choices, but also by the choices that other agents make. Such an influence is called an externality. Whereas ...

  7. Organizing for External Knowledge Sourcing

    DEFF Research Database (Denmark)

    Rabbiosi, Larissa; Reichstein, Toke

    2011-01-01

    The aim of this article is to provide an introduction to the special issue. We briefly consider the external knowledge sourcing and organizing for innovation literatures, which offer a background for the special issue, and we highlight their mutual dialogue. We then illustrate the main findings o...

  8. Externally studentized normal midrange distribution

    Directory of Open Access Journals (Sweden)

    Ben Dêivide de Oliveira Batista

    Full Text Available ABSTRACT The distribution of externally studentized midrange was created based on the original studentization procedures of Student and was inspired in the distribution of the externally studentized range. The large use of the externally studentized range in multiple comparisons was also a motivation for developing this new distribution. This work aimed to derive analytic equations to distribution of the externally studentized midrange, obtaining the cumulative distribution, probability density and quantile functions and generating random values. This is a new distribution that the authors could not find any report in the literature. A second objective was to build an R package for obtaining numerically the probability density, cumulative distribution and quantile functions and make it available to the scientific community. The algorithms were proposed and implemented using Gauss-Legendre quadrature and the Newton-Raphson method in R software, resulting in the SMR package, available for download in the CRAN site. The implemented routines showed high accuracy proved by using Monte Carlo simulations and by comparing results with different number of quadrature points. Regarding to the precision to obtain the quantiles for cases where the degrees of freedom are close to 1 and the percentiles are close to 100%, it is recommended to use more than 64 quadrature points.

  9. Measuring Externalities in Program Evaluation

    NARCIS (Netherlands)

    Janssens, Wendy

    2005-01-01

    Impact evaluations of development programmes usually focus on a comparison of participants with a control group. However, if the programme generates externalities for non-participants such an approach will capture only part of the programme's impact. Based on a unique large-scale quantitative survey

  10. External noise distinguishes attention mechanisms.

    Science.gov (United States)

    Lu, Z L; Dosher, B A

    1998-05-01

    We developed and tested a powerful method for identifying and characterizing the effect of attention on performance in visual tasks as due to signal enhancement, distractor exclusion, or internal noise suppression. Based on a noisy Perceptual Template Model (PTM) of a human observer, the method adds increasing amounts of external noise (white gaussian random noise) to the visual stimulus and observes the effect on performance of a perceptual task for attended and unattended stimuli. The three mechanisms of attention yield three "signature" patterns of performance. The general framework for characterizing the mechanisms of attention is used here to investigate the attentional mechanisms in a concurrent location-cued orientation discrimination task. Test stimuli--Gabor patches tilted slightly to the right or left--always appeared on both the left and the right of fixation, and varied independently. Observers were cued on each trial to attend to the left, the right, or evenly to both stimuli, and decide the direction of tilt of both test stimuli. For eight levels of added external noise and three attention conditions (attended, unattended, and equal), subjects' contrast threshold levels were determined. At low levels of external noise, attention affected threshold contrast: threshold contrasts for non-attended stimuli were systematically higher than for equal attention stimuli, which were, in turn, higher than for attended stimuli. Specifically, when the rms contrast of the external noise is below 10%, there is a consistent 17% elevation of contrast threshold from attended to unattended condition across all three subjects. For higher levels of external noise, attention conditions did not affect threshold contrast values at all. These strong results are characteristic of a signal enhancement, or equivalently, an internal additive noise reduction mechanism of attention.

  11. Technical basis document for external events

    International Nuclear Information System (INIS)

    OBERG, B.D.

    2003-01-01

    This document supports the Tank Farms Documented Safety Analysis and presents the technical basis for the FR-equencies of externally initiated accidents. The consequences of externally initiated events are discussed in other documents that correspond to the accident that was caused by the external event. The external events include aircraft crash, vehicle accident, range fire, and rail accident

  12. Use of Automated External Defibrillators

    Energy Technology Data Exchange (ETDEWEB)

    Gregory K Christensen

    2009-02-01

    In an effort to improve survival from cardiac arrest, the American Heart Association (AHA) has promoted the Chain of Survival concept, describing a sequence of prehospital steps that result in improved survival after sudden cardiac arrest. These interventions include immediate deployment of emergency medical services, prompt cardiopulmonary resuscitation, early defibrillation when indicated, and early initiation of advanced medical care. Early defibrillation has emerged as the most important intervention with survival decreasing by 10% with each minute of delay in defibrillation. Ventricular Fibrillation (VF) is a condition in which there is uncoordinated contraction of the heart cardiac muscle of the ventricles in the heart, making them tremble rather than contract properly. VF is a medical emergency and if the arrhythmia continues for more than a few seconds, blood circulation will cease, and death can occur in a matter of minutes. During VF, contractions of the heart are not synchronized, blood flow ceases, organs begin to fail from oxygen deprivation and within 10 minutes, death will occur. When VF occurs, the victim must be defibrillated in order to establish the heart’s normal rhythm. On average, the wait for an ambulance in populated areas of the United States is about 11 minutes. In view of these facts, the EFCOG Electrical Safety Task Group initiated this review to evaluate the potential value of deployment and use of automated external defibrillators (AEDs) for treatment of SCA victims. This evaluation indicates the long term survival benefit to victims of SCA is high if treated with CPR plus defibrillation within the first 3-5 minutes after collapse. According to the American Heart Association (AHA), survival rates as high as 74% are possible if treatment and defibrillation is performed in the first 3 minutes. In contrast survival rates are only 5% where no AED programs have been established to provide prompt CPR and defibrillation. ["CPR statistics

  13. Associação entre comportamentos externalizantes e baixo desempenho escolar: uma revisão de estudos prospectivos e longitudinais Association between externalizing behavior and underachievement: a review of prospective and longitudinal studies

    Directory of Open Access Journals (Sweden)

    Lylla Cysne Frota D'Abreu

    2010-04-01

    Full Text Available Foi feito um levantamento na literatura de estudos prospectivos e longitudinais investigando a associação entre problemas de comportamento externalizantes e baixo desempenho escolar no ensino fundamental, no período de 1990 a 2006. Por meio dos sistemas PsycInfo, Medline, Lilacs, Scielo e Web of Science, foram selecionados e adquiridos 18 artigos, classificados em quatro categorias: estudos com amostras clínicas; estudos comparando grupos com ou sem comorbidade; estudos que buscam testar modelos de trajetória de desenvolvimento; estudos sobre precursores da associação entre problemas de comportamento e baixo desempenho escolar. A análise dos artigos evidencia que a co-ocorrência de baixo desempenho escolar e problemas externalizantes sugere a influência de variáveis antecedentes, como condições adversas na família e baixo nível socioeconômico. Indica, ainda, que a associação traz mau prognóstico às crianças, como comorbidades com transtornos psiquiátricos, posteriores problemas acadêmicos e de comportamento anti-social, evidenciando a situação de risco psicossocial em que se encontram.A survey in the literature of prospective and longitudinal studies was made investigating the association between externalizing behavior and underachievement in the period of 1990-2006. It was used PsycInfo, Medline, Lilacs, Scielo and Web of Science systems and it was selected and acquired 18 articles, classified in four categories: studies with clinical samples; studies comparing groups with or without comorbidity; studies that try to establish or to test models of developmental trajectory; studies of precursors of the association between behavior problems and underachievement. The analysis of articles evidences that the co-occurrence of underachievement and externalizing behavior suggests the influence of antecedent variables, such as adverse conditions in the family and low socio-economic level. It indicates that the association brings

  14. Results of a Quality Assurance Review of External Beam Radiation Therapy in the International Society of Paediatric Oncology (Europe) Neuroblastoma Group's High-risk Neuroblastoma Trial: A SIOPEN Study

    International Nuclear Information System (INIS)

    Gaze, Mark N.; Boterberg, Tom; Dieckmann, Karin; Hörmann, Marcus; Gains, Jennifer E.; Sullivan, Kevin P.; Ladenstein, Ruth

    2013-01-01

    Purpose: Radiation therapy is important for local control in neuroblastoma. This study reviewed the compliance of plans with the radiation therapy guidelines of the International Society of Paediatric Oncology (Europe) Neuroblastoma Group (SIOPEN) High-Risk Trial protocol. Methods and Materials: The SIOPEN trial central electronic database has sections to record diagnostic imaging and radiation therapy planning data. Individual centers may upload data remotely, but not all centers involved in the trial chose to use this system. A quality scoring system was devised based on how well the radiation therapy plan matched the protocol guidelines, to what extent deviations were justified, and whether adverse effects may result. Central review of radiation therapy planning was undertaken retrospectively in 100 patients for whom complete diagnostic and treatment sets were available. Data were reviewed and compared against protocol guidelines by an international team of radiation oncologists and radiologists. For each patient in the sample, the central review team assigned a quality assurance score. Results: It was found that in 48% of patients there was full compliance with protocol requirements. In 29%, there were deviations for justifiable reasons with no likely long-term adverse effects resulting. In 5%, deviations had occurred for justifiable reasons, but that might result in adverse effects. In 1%, there was a deviation with no discernible justification, which would not lead to long-term adverse events. In 17%, unjustified deviations were noted, with a risk of an adverse outcome resulting. Conclusions: Owing to concern over the proportion of patients in whom unjustified deviations were observed, a protocol amendment has been issued. This offers the opportunity for central review of radiation therapy plans before the start of treatment and the treating clinician a chance to modify plans.

  15. Results of a Quality Assurance Review of External Beam Radiation Therapy in the International Society of Paediatric Oncology (Europe) Neuroblastoma Group's High-risk Neuroblastoma Trial: A SIOPEN Study

    Energy Technology Data Exchange (ETDEWEB)

    Gaze, Mark N., E-mail: mark.gaze@uclh.nhs.uk [Department of Oncology, University College London Hospitals NHS Foundation Trust, London (United Kingdom); Boterberg, Tom [Department of Radiation Oncology, Ghent University Hospital, Ghent (Belgium); Dieckmann, Karin; Hoermann, Marcus [General Hospital Vienna, Medical University Vienna (Austria); Gains, Jennifer E.; Sullivan, Kevin P. [Department of Oncology, University College London Hospitals NHS Foundation Trust, London (United Kingdom); Ladenstein, Ruth [Children' s Cancer Research Institute, St. Anna Children' s Hospital, Vienna (Austria)

    2013-01-01

    Purpose: Radiation therapy is important for local control in neuroblastoma. This study reviewed the compliance of plans with the radiation therapy guidelines of the International Society of Paediatric Oncology (Europe) Neuroblastoma Group (SIOPEN) High-Risk Trial protocol. Methods and Materials: The SIOPEN trial central electronic database has sections to record diagnostic imaging and radiation therapy planning data. Individual centers may upload data remotely, but not all centers involved in the trial chose to use this system. A quality scoring system was devised based on how well the radiation therapy plan matched the protocol guidelines, to what extent deviations were justified, and whether adverse effects may result. Central review of radiation therapy planning was undertaken retrospectively in 100 patients for whom complete diagnostic and treatment sets were available. Data were reviewed and compared against protocol guidelines by an international team of radiation oncologists and radiologists. For each patient in the sample, the central review team assigned a quality assurance score. Results: It was found that in 48% of patients there was full compliance with protocol requirements. In 29%, there were deviations for justifiable reasons with no likely long-term adverse effects resulting. In 5%, deviations had occurred for justifiable reasons, but that might result in adverse effects. In 1%, there was a deviation with no discernible justification, which would not lead to long-term adverse events. In 17%, unjustified deviations were noted, with a risk of an adverse outcome resulting. Conclusions: Owing to concern over the proportion of patients in whom unjustified deviations were observed, a protocol amendment has been issued. This offers the opportunity for central review of radiation therapy plans before the start of treatment and the treating clinician a chance to modify plans.

  16. External cephalic version-related risks: a meta-analysis.

    Science.gov (United States)

    Grootscholten, Kim; Kok, Marjolein; Oei, S Guid; Mol, Ben W J; van der Post, Joris A

    2008-11-01

    To systematically review the literature on external cephalic version-related complications and to assess if the outcome of a version attempt is related to complications. In March 2007 we searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. Studies reporting on complications from an external cephalic version attempt for singleton breech pregnancies after 36 weeks of pregnancy were selected. We calculated odds ratios (ORs) from studies that reported both on complications as well as on the position of the fetus immediately after the procedure. We found 84 studies, reporting on 12,955 version attempts that reported on external cephalic version-related complications. The pooled complication rate was 6.1% (95% CI 4.7-7.8), 0.24% for serious complications (95% confidence interval [CI] 0.17-0.34) and 0.35% for emergency cesarean deliveries (95% CI 0.26-0.47). Complications were not related to external cephalic version outcome (OR 1.2 (95% CI 0.93-1.7). External cephalic version is a safe procedure. Complications are not related to the fetal position after external cephalic version.

  17. Applications of contrast enhanced CT through external jugular access

    International Nuclear Information System (INIS)

    Xu Qiaolan; Zou Wenxing; Chen Meixia; Xie Hongbo

    2005-01-01

    Objective: A retrospective analysis and evaluation for the effects of contrast enhanced computed tomography through external jugular access. Methods: 1250 cases (male 692 and female 558) underwent CT contrast enhanced examination were retrospectively reviewed from May, 2002 to Oct, 2002. The patients aged from 12 to 86 years, averagely 49 years. Contrast agent (Ultravist) was given through an intravenous catheter placed in the cubital vein. Precise injection rates were ensured by a power injector (Medrad MCT310, USA). Excellent enhancement was achieved with this protocol in most of the patients, while external jugular access was established in 96 cases because it was unable to setup a cubital venous access. Results: Good enhancement were acquired when 96 cases of contrast agent injected through external jugular vein. And the external jugular access was setup successfully with a single puncture. Conclusion: It is a common occasion when patient undergoing contrast enhanced CT scan is in poor conditions: debility, cachexia, or with complication of chemotherapy or radiation therapy, which often results in invalidity of cabital venous access, and consequently, making bolus injection impossible. The external jugular vein is a large and central blood vessel, which is easy to setup an access. In our experience, an external jugular access should be recommended as a substitution if the cubital venous access is not available. (authors)

  18. Applications of contrast enhanced CT through external jugular access

    Energy Technology Data Exchange (ETDEWEB)

    Qiaolan, Xu; Wenxing, Zou; Meixia, Chen; Hongbo, Xie [The First Affiliated Hospital of Sun Yat-sen University, Guangzhou (China). Dept. of Radiology

    2005-09-15

    Objective: A retrospective analysis and evaluation for the effects of contrast enhanced computed tomography through external jugular access. Methods: 1250 cases (male 692 and female 558) underwent CT contrast enhanced examination were retrospectively reviewed from May, 2002 to Oct, 2002. The patients aged from 12 to 86 years, averagely 49 years. Contrast agent (Ultravist) was given through an intravenous catheter placed in the cubital vein. Precise injection rates were ensured by a power injector (Medrad MCT310, USA). Excellent enhancement was achieved with this protocol in most of the patients, while external jugular access was established in 96 cases because it was unable to setup a cubital venous access. Results: Good enhancement were acquired when 96 cases of contrast agent injected through external jugular vein. And the external jugular access was setup successfully with a single puncture. Conclusion: It is a common occasion when patient undergoing contrast enhanced CT scan is in poor conditions: debility, cachexia, or with complication of chemotherapy or radiation therapy, which often results in invalidity of cabital venous access, and consequently, making bolus injection impossible. The external jugular vein is a large and central blood vessel, which is easy to setup an access. In our experience, an external jugular access should be recommended as a substitution if the cubital venous access is not available. (authors)

  19. External costs of energy - do the answers match the questions? Looking back at 10 years of ExternE

    International Nuclear Information System (INIS)

    Krewitt, W.

    2002-01-01

    While the claim for 'getting prices right' is quite popular in conceptual policy papers, the implementation of appropriate internalisation strategies is still hampered by a lack of reliable external cost data. Great expectations were set into the ExternE project, a major research programme launched by the European Commission at the beginning of the 1990s to provide a scientific basis for the quantification of energy related externalities and to give guidance supporting the design of internalisation measures. After more than a decade of research, the ExternE label became a well recognised standard source for external cost data. Looking back into the ExternE history, the paper pursues how emerging new scientific insights and changing background assumptions affected external cost estimates and related recommendations to policy over time. Based on ExternE results, the usefulness and inherent limitations of external cost estimates for impact categories like climate change or nuclear waste disposal is discussed. The paper also gives examples on how external costs in spite of remaining uncertainties are successfully used to support environmental policy. (Author)

  20. External costs of electricity production under scrutiny

    International Nuclear Information System (INIS)

    Wagner, H.J.; Melchert, A.

    1993-01-01

    After a short introduction into the problems and questions surrounding the issue of external costs Chapter 2 presents the most important results of the studies under review and analysis in this work. Occasionally, minor discrepancies were found between the results given in the summary of a study and the data reported in the relevant chapters. Chapter 3 identifies and discusses differences in perspective between the studies under consideration. Chapter 4 analyses the most important premises and parameters adopted in the studies for the calculation of overall costs and net benefits of the different modes of electricity production. This serves to probe the reliability of the data, plausibility of the premises, and nature of the presupposed relationships. Chapter 5 examines the relationships of time assumed in the studies and gives a first comment on the more advanced Prognos study. Chapter 6, finally, offers a summarizing evaluation. (orig./UA) [de

  1. Firm Search for External Knowledge

    DEFF Research Database (Denmark)

    Sofka, Wolfgang; Grimpe, Christoph

    2012-01-01

    ignored the institutional context that provides or denies access to external knowledge at the country level. Combining institutional and knowledge search theory, we suggest that the market orientation of the institutional environment and the magnitude of institutional change influence when firms begin......The innovation performance of modern firms is increasingly determined by their ability to search and absorb external knowledge. However, after a certain threshold firms "oversearch" their environment and innovation performance declines. In this paper, we argue that prior literature has largely...... to experience the negative performance effects of oversearch. Based on a comprehensive sample of almost 8,000 firms from ten European countries, we find that institutions matter considerably for firms' search activity. Higher market orientation of institutions increases the effectiveness of firms' search...

  2. MGR External Events Hazards Analysis

    International Nuclear Information System (INIS)

    Booth, L.

    1999-01-01

    The purpose and objective of this analysis is to apply an external events Hazards Analysis (HA) to the License Application Design Selection Enhanced Design Alternative 11 [(LADS EDA II design (Reference 8.32))]. The output of the HA is called a Hazards List (HL). This analysis supersedes the external hazards portion of Rev. 00 of the PHA (Reference 8.1). The PHA for internal events will also be updated to the LADS EDA II design but under a separate analysis. Like the PHA methodology, the HA methodology provides a systematic method to identify potential hazards during the 100-year Monitored Geologic Repository (MGR) operating period updated to reflect the EDA II design. The resulting events on the HL are candidates that may have potential radiological consequences as determined during Design Basis Events (DBEs) analyses. Therefore, the HL that results from this analysis will undergo further screening and analysis based on the criteria that apply during the performance of DBE analyses

  3. Personnel external dose monitoring system

    International Nuclear Information System (INIS)

    Zhao Hengyuan

    1989-01-01

    The status and trend of personnel external dose monitoring system are introduced briefly. Their characteristics, functions and TLD bedges of some commercially available automatic TLD system, including UD-710A (Matsushita, Japan), Harshaw-2271, 2276 (Harshaw, USA), Harshaw-8000 (Harshaw/Filtrol), Studsvik-1313 (Sweden) and Pitman-800 (UK) were depicted in detail. Finally, personnel dose management and record keeping system were presented and two examples were given

  4. Materiality and external assurance in corporate sustainability reporting: An exploratory study of UK house builders

    OpenAIRE

    Jones, Peter; Comfort, Daphne; Hillier, David

    2015-01-01

    This paper provides a preliminary examination of the extent to which the UK’s leading house builders are embracing the concept of materiality and commissioning independent external assurance as part of their sustainability reporting processes and to offer some wider reflections on materiality and external assurance in sustainability reporting.\\ud \\ud The paper begins with a review of the characteristics of materiality and external assurance and a brief outline of house building in the UK and ...

  5. External fixation of "intertrochanteric" fractures.

    Science.gov (United States)

    Gani, Naseem Ul; Kangoo, Khursheed Ahmed; Bashir, Arshad; Muzaffer, Rahil; Bhat, Mohammad Farooq; Farooq, Munir; Badoo, Abdul Rashid; Dar, Imtiyaz Hussian; Wani, Mudassir Maqbool

    2009-10-10

    In developing countries, due to limited availability of modern anesthesia and overcrowding of the hospitals with patients who need surgery, high-risk patients with "intertrochanteric" fractures remain unsuita ble for open reduction and internal fixation.The aim of this study was to analyze the results of external fixation of "intertrochanteric" fractures in high-risk geriatric patients in a developing country.The results of 62 ambulatory high-risk geriatric patients with a mean age of 70 years (range 58-90 years) with "intertrochanteric" fractures, in whom external fixation was performed, are reported.Eight patients died during follow-up due to medical causes unrelated to the surgical procedure. So only 54 patients were available for final assessment. Procedure is simple, performed under local anesthesia, requires less time for surgery and is associated with less blood loss. Good fixation and early ambulation was achieved in most of the patients. Average time to union was 14 weeks. Thirty-one patients developed superficial pin tract infection and 28 patients had average shortening of 15 mm due to impaction and varus angulation. Functional outcome was assessed using Judet's point system. Good to excellent results were achieved in 44 patients.This study demonstrated that external fixation of "intertrochantric" fractures performed under local anesthesia offers significant advantage in ambulatory high-risk geriatric patients especially in a developing country.

  6. External-stimuli responsive systems for cancer theranostic

    Directory of Open Access Journals (Sweden)

    Jianhui Yao

    2016-10-01

    Full Text Available The upsurge of novel nanomaterials and nanotechnologies has inspired the researchers who are striving for designing safer and more efficient drug delivery systems for cancer therapy. Stimuli responsive nanomaterial offered an alternative to design controllable drug delivery system on account of its spatiotemporally controllable properties. Additionally, external stimuli (light, magnetic field and ultrasound could develop into theranostic applications for personalized medicine use because of their unique characteristics. In this review, we give a brief overview about the significant progresses and challenges of certain external-stimuli responsive systems that have been extensively investigated in drug delivery and theranostics within the last few years.

  7. External and internal radiation therapy: Past and future directions

    Directory of Open Access Journals (Sweden)

    Sadeghi Mahdi

    2010-01-01

    Full Text Available Cancer is a leading cause of morbidity and mortality in the modern world. Treatment modalities comprise radiation therapy, surgery, chemotherapy and hormonal therapy. Radiation therapy can be performed by using external or internal radiation therapy. However, each method has its unique properties which undertakes special role in cancer treatment, this question is brought up that: For cancer treatment, whether external radiation therapy is more efficient or internal radiation therapy one? To answer this question, we need to consider principles and structure of individual methods. In this review, principles and application of each method are considered and finally these two methods are compared with each other.

  8. Audit Oversight: Followup Review of the Military Department Audit Agencies Peer Review

    National Research Council Canada - National Science Library

    2004-01-01

    .... The external quality control review should determine whether the reviewed audit organization's internal quality control system was adequate and operating effectively to provide reasonable assurance...

  9. 25 CFR 23.46 - Financial management, internal and external controls and other assurances.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Financial management, internal and external controls and....46 Financial management, internal and external controls and other assurances. Grantee financial... required by the grantee's financial management system. The Secretary or his/her designee may review the...

  10. Analysis of the Impact of External Debt on Economic Growth in an ...

    African Journals Online (AJOL)

    Analysis of the Impact of External Debt on Economic Growth in an Emerging Economy: Evidence from Nigeria. ... African Research Review ... Findings reveal that debt service payment has negative and insignificant impact on Nigeria's economic growth while external debt stock has positive and significant effect on Nigeria's ...

  11. 46,XY DSD with Female or Ambiguous External Genitalia at Birth due to Androgen Insensitivity Syndrome, 5-Reductase-2 Deficiency, or 17-Hydroxysteroid Dehydrogenase Deficiency: A Review of Quality of Life Outcomes

    Directory of Open Access Journals (Sweden)

    Mazur Tom

    2009-08-01

    Full Text Available Disorders of sex development refer to a collection of congenital conditions in which atypical development of chromosomal, gonadal, or anatomic sex occurs. Studies of 46,XY DSD have focused largely on gender identity, gender role, and sexual orientation. Few studies have focused on other domains, such as physical and mental health, that may contribute to a person's quality of life. The current review focuses on information published since 1955 pertaining to psychological well-being, cognition, general health, fertility, and sexual function in people affected by androgen insensitivity syndromes, 5- reductase-2 deficiency, or 17-hydroxysteroid dehydrogenase-3 deficiency—reared male or female. The complete form of androgen insensitivity syndrome has been the focus of the largest number of investigations in domains other than gender. Despite this, all of the conditions included in the current review are under-studied. Realms identified for further study include psychological well-being, cognitive abilities, general health, fertility, and sexual function. Such investigations would not only improve the quality of life for those affected by DSD but may also provide information for improving physical and mental health in the general population.

  12. Sperm motility of externally fertilizing fish and amphibians.

    Science.gov (United States)

    Browne, R K; Kaurova, S A; Uteshev, V K; Shishova, N V; McGinnity, D; Figiel, C R; Mansour, N; Agney, D; Wu, M; Gakhova, E N; Dzyuba, B; Cosson, J

    2015-01-01

    We review the phylogeny, sperm competition, morphology, physiology, and fertilization environments of the sperm of externally fertilizing fish and amphibians. Increased sperm competition in both fish and anurans generally increases sperm numbers, sperm length, and energy reserves. The difference between the internal osmolarity and iconicity of sperm cells and those of the aquatic medium control the activation, longevity, and velocity of sperm motility. Hypo-osmolarity of the aquatic medium activates the motility of freshwater fish and amphibian sperm and hyperosmolarity activates the motility of marine fish sperm. The average longevity of the motility of marine fish sperm (~550 seconds) was significantly (P amphibian sperm in general and anurans reversion from internal to external fertilization. Our findings provide a greater understanding of the reproductive biology of externally fertilizing fish and amphibians, and a biological foundation for the further development of reproduction technologies for their sustainable management.

  13. Dynamic ultrasound of the external snapping hip syndrome

    International Nuclear Information System (INIS)

    Choi, Yun Sun; Song, Baek Yong; Paik, Sang Hyun; Lee, Tae Gyu; Yoon, Yong Kyu; Lee, Sung Moon

    2002-01-01

    Snapping hip syndrome has been described as a hip pain accompanied by an audible snapping during motion of the hip or while walking. The variable causes of its external, internal, and intra-articular origins have been described. The most common extemal snapping hip has been associated with a thickened posterior border of the iliotibial band or of the anterior border of the gluteus maximus muscle slipping over the greater trochanter. The aim of this study was to evaluate the dynamic ultrasound findings of external snapping hip syndrome with review of the literature. We studied 5 patients (7 cases) with external snapping hip and pain over the greater trochanter during walking or hip motion (3 males and 2 females, age range, 14-32 years; mean, 19 years). Two patients reported bilateral snapping hips.

  14. Electric utility resource expansion planning using environmental externalities

    International Nuclear Information System (INIS)

    Mitchell, D.

    1992-01-01

    This paper describes the recent experience of San Diego Gas ampersand Electric Company using environmental externalities in the expansion planning of its electrical system. This is the first time that this method of planning has been used in the electric utility industry in California. The paper reviews the conceptual development of the monetary values for environmental externalities and shows how the application of these values modifies the resource selection process. This paper should be of interest to professionals involved in policy issues relating to the use of environmental externalities as a means to improve the environment. The experience gained through this analyses should also benefit electric utility personnel involved in planning, and regulators interested in planning

  15. Estimating location without external cues.

    Directory of Open Access Journals (Sweden)

    Allen Cheung

    2014-10-01

    Full Text Available The ability to determine one's location is fundamental to spatial navigation. Here, it is shown that localization is theoretically possible without the use of external cues, and without knowledge of initial position or orientation. With only error-prone self-motion estimates as input, a fully disoriented agent can, in principle, determine its location in familiar spaces with 1-fold rotational symmetry. Surprisingly, localization does not require the sensing of any external cue, including the boundary. The combination of self-motion estimates and an internal map of the arena provide enough information for localization. This stands in conflict with the supposition that 2D arenas are analogous to open fields. Using a rodent error model, it is shown that the localization performance which can be achieved is enough to initiate and maintain stable firing patterns like those of grid cells, starting from full disorientation. Successful localization was achieved when the rotational asymmetry was due to the external boundary, an interior barrier or a void space within an arena. Optimal localization performance was found to depend on arena shape, arena size, local and global rotational asymmetry, and the structure of the path taken during localization. Since allothetic cues including visual and boundary contact cues were not present, localization necessarily relied on the fusion of idiothetic self-motion cues and memory of the boundary. Implications for spatial navigation mechanisms are discussed, including possible relationships with place field overdispersion and hippocampal reverse replay. Based on these results, experiments are suggested to identify if and where information fusion occurs in the mammalian spatial memory system.

  16. External cephalic version facilitation for breech presentation at term.

    Science.gov (United States)

    Hofmeyr, G J

    2001-01-01

    Tocolytic drugs to relax the uterus as well as other methods have been also used in an attempt to facilitate external cephalic version at term. The objective of this review is to assess the effects of routine tocolysis, fetal acoustic stimulation, epidural or spinal analgesia and transabdominal amnioinfusion for external cephalic version at term on successful version and measures of pregnancy outcome. The Cochrane Pregnancy and Childbirth Group Trials Register and the Cochrane Controlled Trials Register were searched. Date of last search: April 2001. Randomised and quasi-randomised trials comparing routine versus selective tocolysis; fetal acoustic stimulation in midline fetal spine positions versus dummy or no stimulation; epidural or spinal analgesia versus no regional analgesia; or transabdominal amnioinfusion versus no amnioinfusion for external cephalic version at term. Eligibility and trial quality were assessed by the reviewer. In seven trials, routine tocolysis was associated with fewer failures of external cephalic version (relative risk 0.74, 95% confidence interval 0.64 to 0.87). There were no significant differences between non-cephalic presentations at birth. Caesarean sections were reduced (relative risk 0.85, confidence interval 0.72-0.99). Fetal acoustic stimulation in midline fetal spine positions was associated with fewer failures of external cephalic version at term (relative risk 0.17, 95% confidence interval 0.05 to 0.60). With epidural or spinal analgesia, external cephalic version failure, non-cephalic births and caesarean sections were reduced in one trial but not the other. The overall differences were not statistically significant. No randomised trials of transabdominal amnioinfusion for external cephalic version at term were located. Routine tocolysis appears to reduce the failure rate of external cephalic version at term. Although promising, there is not enough evidence to evaluate the use of fetal acoustic stimulation in midline fetal

  17. Matchings with Externalities and Attitudes

    DEFF Research Database (Denmark)

    Branzei, Simina; Michalak, Tomasz; Rahwan, Talal

    2013-01-01

    Two-sided matchings are an important theoretical tool used to model markets and social interactions. In many real-life problems the utility of an agent is influenced not only by their own choices, but also by the choices that other agents make. Such an influence is called an externality. Whereas ...... where agents take different attitudes when reasoning about the actions of others. In particular, we study optimistic, neutral and pessimistic attitudes and provide both computational hardness results and polynomial-time algorithms for computing stable outcomes....

  18. Nuclear energy and external constraints

    International Nuclear Information System (INIS)

    Lattes, R.; Thiriet, L.

    1983-01-01

    The structural factors of this crisis probably predominate over factors arising out the economic situation, even if explanations vary in this respect. In this article devoted to nuclear energy, a possible means of Loosering external constraints the current international economic environment is firstly outlined; the context in which the policies of industrialized countries, and therefore that of France, must be developed. An examination of the possible role of energy policies in general and nuclear policies in particular as an instrument of economic policy in providing a partial solution to this crisis, will then enable to quantitatively evaluate the effects of such policies at a national level [fr

  19. Influence of greenhouse climate and plant density on external quality of chrysanthemum (Dendranthema grandiflorum (Ramat.)Kitamura) : First steps towards a quality model

    NARCIS (Netherlands)

    Carvalho, S.M.P.; Heuvelink, E.

    2001-01-01

    The effects of greenhouse climate and plant density on external quality of chrysanthemum (Dendranthema grandiflorum syn. Chrysanthemum morifolium) are reviewed. The external quality aspects analysed in this paper are stem morphology (length, diameter and "strength"), leaf morphology (number and

  20. An Improved Plutonium Trifluoride Precipitation Flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, H.D.

    2001-06-26

    This report discusses results of the plutonium trifluoride two-stage precipitation study. A series of precipitation experiments was used to identify the significant process variables affecting precipitation performance. A mathematical model of the precipitation process was developed which is based on the formation of plutonium fluoride complexes. The precipitation model relates all process variables, in a single equation, to a single parameter which can be used to control the performance of the plutonium trifluoride precipitation process. Recommendations have been made which will optimize the FB-Line plutonium trifluoride precipitation process.

  1. An Improved Plutonium Trifluoride Precipitation Flowsheet

    International Nuclear Information System (INIS)

    Harmon, H.D.

    2001-01-01

    This report discusses results of the plutonium trifluoride two-stage precipitation study. A series of precipitation experiments was used to identify the significant process variables affecting precipitation performance. A mathematical model of the precipitation process was developed which is based on the formation of plutonium fluoride complexes. The precipitation model relates all process variables, in a single equation, to a single parameter which can be used to control the performance of the plutonium trifluoride precipitation process. Recommendations have been made which will optimize the FB-Line plutonium trifluoride precipitation process

  2. Pyrochemistry: from flowsheet to industrial facility

    International Nuclear Information System (INIS)

    Donaldson, N.; Thied, R.; Lamorlette, G.; Greneche, D.

    2001-01-01

    Challenges to any future commercial deployment of pyro-chemistry will be significant. The implications of industrial use must be well understood in technical, economic and social terms to gain commercial and regulatory acceptance. The broad base of knowledge necessary to support general commercial use of pyro-chemistry in the nuclear field is considered. Pyro-chemistry development is discussed in the context of a commercial application-based approach and issues to be addressed are outlined. A stepwise evolutionary development of pyro-chemical processing is anticipated which might allow industrialization in the absence of acceptance of evolutionary development at industrial scale which benefited Purex development. (author)

  3. Waveguide based external cavity semiconductor lasers

    NARCIS (Netherlands)

    Oldenbeuving, Ruud; Klein, E.J.; Offerhaus, Herman L.; Lee, Christopher James; Verhaegen, M.; Boller, Klaus J.

    2012-01-01

    We report on progress of the project waveguide based external cavity semiconductor laser (WECSL) arrays. Here we present the latest results on our efforts to mode lock an array of tunable, external cavity semiconductor lasers.

  4. Review of SR-Can: Evaluation of SKB's handling of spent fuel performance, radionuclide chemistry and geosphere transport parameters. External review contribution in support of SKI's and SSI's review of SR-Can

    Energy Technology Data Exchange (ETDEWEB)

    Stenhouse, Mike (Monitor Scientific LLC, Denver, CO (US)); Jegou, Christophe (Commissariat a l' Energie Atomique (CEA) (FR)); Brown, Paul (Geochem Australia (AU)); Meinrath, Guenther (RER Consultants, Passau (DE)); Nitsche, Heino (Univ. of California, Berkeley (US)); Ekberg, Christian (Chalmers University of Technology (SE))

    2008-03-15

    SR-Can covers the containment phase of the KBS-3 barriers as well as the consequences of releases of radionuclides to the rock and eventually the biosphere (after complete containment within fuel canisters has partially failed). The aim of this report is to provide a range of review comments with respect to those parameters related to spent fuel performance as well as radionuclide chemistry and transport. These parameter values are used in the quantification of consequences due to release of radionuclides from potentially leaking canisters. The report does not cover modelling approaches used for quantification of consequences. However, modelling used to derive parameter values is to some extent addressed (such as calculation of maximum radionuclide concentration due to formation of solubility limiting phases). The following are the key highlights and comments generated in the course of the review: Inconsistencies exist between recommendations provided in technical reports and those quoted in the Data Report. One of the reasons for such inconsistencies has been the timing of different pieces of research. It is hoped that the timing of contributions to SR-Site will be such that these inconsistencies can be avoided. Sensitivity analyses need to be carried out and reported in a number of areas to support some of the assumptions or decisions made in the assessment calculations. The likelihood is that SKB has performed many of the sensitivity analyses identified in different parts of this report, but these need to be reported, preferably to complement the recommendations provided

  5. Externalities and carbon taxes: Status and impacts on coal use

    International Nuclear Information System (INIS)

    Davis, R.J.

    1993-01-01

    More than half of the Nation's public utility commissions have developed, are developing, or are seriously considering the use of environmental externalities in the selection of new electric power generation. Most externality-based resource planning approaches heavily penalize carbon dioxide emissions and therefore the externality issue is linked closely to the issue of carbon taxes. Several foreign countries have instituted carbon taxes and many state and federal legislators and policy makers favor carbon taxes as a means of reducing carbon dioxide emissions which are believed to play a major role in future global warming. Both externalities and carbon taxes will have a disproportionate and a significant impact on future coal use because of the relatively higher proportion of carbon in coal compared to other fossil fuels and the absence of carbon in other means of electricity generation. The purpose of this paper is twofold: (1) to report on the status of carbon taxes and externality-based electric utility resource allocation requirements around the world with an emphasis on the US, and (2) to present a review of the literature dealing with estimated impacts of these policies on coal use, in general, and the deployment of specific coal-using technologies in particular

  6. Effect of Cervical Siphon of External and Internal Carotid Arteries.

    Science.gov (United States)

    Singh, Rajani; Tubbs, Richard Shane

    2017-10-01

    Variant courses, configuration, and branching pattern of the external and internal carotid arteries, especially when curved in S-shape, are important for hemodynamic changes and clinical implications. Therefore, the aim of the study is to report abnormal cervical siphons observed in external and internal carotid arteries to explore clinical significance by review of literature and hemodynamic changes theoretically.The right common carotid artery bifurcated into external and internal carotid arteries at the level of the upper border of thyroid cartilage in a 70-year-old female cadaver. After bifurcation, the external carotid artery underwent severe tortuosity coursing through 5 bends at points A, B, C, D, and E from its origin to termination and 2 bends at A' and B' in internal carotid artery in the cervical region. The angles between inflow and out flow of the blood at the bends were measured and the change in velocity at each bend was computed for both arteries. Hemodynamic changes were calculated, compared and relevant clinical complications were theoretically correlated.The angles of 20°, 30°, 51°, 52°, 60°, and 28°, 48° were formed by 5 bends of external and 2 bends of internal carotid arteries, respectively. The curved courses of these arteries caused reduction in velocity/stasis, turbulence, and low shear stress. Such kinks might cause stroke, ischemia and mistaken for tumors and abscess in imagery leading to or otherwise producing iatrogenic repercussions. This study will be useful for anatomists, clinicians, and radiologists.

  7. Externalized ileocolic anastomosis: case report.

    Science.gov (United States)

    Simcock, James; Kuntz, Charles A; Newman, Raquel

    2010-01-01

    A 6-year-old, spayed female Labrador retriever was presented 48 hours after an intestinal resection and anastomosis for management of a small intestinal foreign body. Abdominal ultrasound confirmed the presence of peritoneal effusion. Cytology of fluid collected by abdominocentesis revealed a large number of degenerate neutrophils with intracellular cocci. A diagnosis of septic peritonitis was made, presumably because of dehiscence of the anastomosis. Upon repeat exploratory celiotomy, the intestinal anastomosis (located 4 cm orad to the cecum) was found to be leaking intestinal contents into the abdomen. The distal ileum, cecum, and proximal colon were resected. An end-to-end, ileocolic anastomosis was performed and subsequently exteriorized into the subcutaneous space via a paramedian incision through the abdominal wall. The anastomosis was inspected daily for 4 days before it was returned to the abdomen and the subcutaneous defect was closed. Serial cytology of the peritoneal fluid, which was performed during this 4-day postoperative period, confirmed progressive resolution of peritonitis. The dog was discharged from the hospital 2 days following return of the anastomosis into the abdomen. Externalized intestinal anastomosis is used with good success in human medicine for repair of colonic injuries. In this case, externalization of the anastomosis permitted healing of the intestinal anastomosis in an environment isolated from the detrimental effects created by septic peritonitis. In addition, direct visualization of the anastomosis allowed assessment of healing. To our knowledge, this procedure has not been previously reported in companion animals.

  8. Effects of Externalities on Patterns of Exchange

    NARCIS (Netherlands)

    Dijkstra, J.; van Assen, M.A.L.M.

    Many real−life examples of exchanges with externalities exist. Externalities of exchange are defined as direct consequences of exchanges for the payoff of actors who are not involved in the exchange. This paper focuses on how externalities influence the partner choice in exchange networks. In an

  9. The external cruising costs of parking

    NARCIS (Netherlands)

    Inci, E.; van Ommeren, J.N.; Kobus, Martijn

    2017-01-01

    Existing work emphasizes the importance of traffic congestion externalities, but typically ignores cruising-for-parking externalities. We estimate the marginal external cruising costs of parking—that is, the time costs that an additional parked car imposes on drivers by inducing them to cruise for

  10. Stabilization of the external kink and the resistive wall mode

    International Nuclear Information System (INIS)

    Chu, M S; Okabayashi, M

    2010-01-01

    The pursuit of steady-state economic production of thermonuclear fusion energy has led to research on the stabilization of the external kink and the resistive wall mode. Advances in both experiment and theory, together with improvements in diagnostics, heating and feedback methods have led to substantial and steady progress in the understanding and stabilization of these instabilities. Many of the theory and experimental techniques and results that have been developed are useful not only for the stabilization of the resistive wall mode. They can also be used to improve the general performance of fusion confinement devices. The conceptual foundations and experimental results on the stabilization of the external kink and the resistive wall mode are reviewed. (topical review)

  11. External noise when using biofuel

    International Nuclear Information System (INIS)

    Kotaleski, J.

    1994-08-01

    The aim of this study has been to cover sources of noise dealing with all steps in a biofuel chain; producing, transporting, storing and firing the biofuel. When the availability of relevant test results from noise surveys is not so good and mostly badly documented, the study has been concentrated on estimation of external noise for planning and design purposes, from a prospective biofuel-fired plant. A synoptic tabulation of estimated acoustic power levels from different noise sources, has been done. The results from measurements of external noise from different existing combined power and heating plants are tabulated. The Nordic model for simulation of external noise has been used for a prospective plant - VEGA - designed by Vattenfall. The aim has been to estimate its noise pollutions at critical points at the nearest residential area (250 m from the fenced industry area). The software - ILYD - is easy to handle, but knowledge about the model is necessary. A requisite for the reliability is the access to measurements or estimations of different sources of noise, at different levels of octaves from 63 to 8000 Hz. The degree of accuracy increases with the number of broad band sources, that are integrated. Using ILYD with available data, a night limit of 40 dB(A) should be possible to fulfill with good degree of accuracy at VEGA, between 10 pm and 7 am, with good planning and under normal operation conditions. A demand for 35 dB(A) as a limit can be harder to fulfill, especially at mornings from 6 to 7. Noise from heavy vehicles within the plant area is classified as industrial noise and not as road traffic noise. This type of noise depends very much on the way of driving and assumed acceleration. Concerning wheel-mounted loaders, they may then only be used during daytime. The simulations show, that even at daytime from 7 to 6 pm, it would be possible to use an acoustically damped chipping machine, inside the power industry area. 31 refs, 13 figs, tabs, 8

  12. Comparison of Outcomes of Operatively Treated Bicondylar Tibial Plateau Fractures by External Fixation and Internal Fixation

    Directory of Open Access Journals (Sweden)

    CC Chan

    2012-03-01

    Full Text Available The outcome of bicondylar tibial plateau fractures treated with either external fixation (35 patients or internal fixation (24 patients was reviewed. Outcome measures included the Rasmussen score, clinical complications, development of osteoarthritis and the requirement for total knee replacement (TKR. Twenty-two (92% anatomical reductions were achieved in the internal fixation group compared to 27 (77% in the external fixation group. Infective complications were more common in the external fixation group (9 patients, 26% due to pin tract infection. There were no deep infections in the internal fixation group. The mean Rasmussen score was not significantly different (mean score 32 in external fixation and 29 in internal fixation between the two groups and the incidence of osteoarthritis was the same in both groups. Four patients in the external fixation group underwent a TKR compared to 5 patients in the internal fixation group. Bicondylar tibial plateau fractures have similar outcomes following external or internal fixation.

  13. External radiotherapy in thyroid cancer

    International Nuclear Information System (INIS)

    Samuel, A.M.; Shah, D.H.

    1999-01-01

    In the management of thyroid carcinoma (TC) of any histological type, surgery is the primary mode of treatment. The second modality for the management is treatment with radioactive iodine ( 131 I), especially, when the tumor has the ability to concentrate 131 I. External radiotherapy has a limited use in differentiated thyroid carcinoma (DTC). It is useful in the management of bulky residual tissue which is not completely resected, metastatic disease which does not concentrated radioiodine and as a palliative treatment for reliving pain in patients with distant metastases. The ER as an adjuvant treatment in both anaplastic and medullary carcinoma has a significant role to play and should be used more frequently than is presently being advocated and practiced

  14. Next decade in external dosimetry

    International Nuclear Information System (INIS)

    Griffith, R.V.

    1988-01-01

    In recent years, a number of external dosimetry problems have been solved. However, changes in standards and legal concepts relating to the application of dosimetry results will require further enhancements in measurement techniques and philosophy in the next 10 y. The introduction of effective dose equivalent and the legal use of probability of causation will require that much greater attention be given to determination of weighted organ dose from external exposure. An imminent change--an increase in the fast neutron quality factor--will require a new round of technology development in a field that has just received a decade of close scrutiny. For the future, we must take advantage of developments in microelectronics. The use of random access memory (RAM) and metal-on-silicon (MOS) devices as detector elements, particularly for neutron dosimetry, has exciting possibilities that are just beginning to be explored. Advances in microcircuitry are leading, and will continue to lead, in the development of a new generation of small, rugged and smart radiation survey instruments that will make the most of detector data. It has become possible with very compact instruments to obtain energy spectra, linear-energy-transfer (LET) spectra, and quality factors in addition to the usual integrated dosimetric quantities: exposure, absorbed dose, and dose equivalent. These instruments will be reliable and easy to use. The user will be able to select the level of sophistication that is required for any specific application. Moreover, since the processing algorithms can be changed, changes in conversion factors can be accommodated with relative ease. During the next decade, the use of computers will continue to grow in value to the health physicist

  15. Analysis of External Treatment Methods and Technical Characteristics of External Treatment

    Science.gov (United States)

    Zhang, Rui; Miao, Mingsan; Bai, Ming

    2018-01-01

    Chinese medicine external therapy is a treatment method of Chinese medicine with Chinese characteristics. The effect of traditional Chinese medicine external treatment, convenient operation, external treatment and technology has great prospects for development. The traditional Chinese medicine external treatment method and technical characteristics were analyzed.

  16. Differences in methodologies used for externality assessment. Why are the numbers different?

    International Nuclear Information System (INIS)

    Schleisner, Lotte

    1999-06-01

    During the last few years, externalities related to power production technologies have been calculated making use of different methodologies. The external costs may turn out to be very different for the same fuel cycle depending on the methodology that has been used to assess the externalities. The report gives a review of different valuation issues, which are used in different externality studies and focuses on why the numbers often are different for the same fuel cycle, using different methodologies for assessment of the externalities. The review of externality valuation focuses in this report on the assessment of environmental externalities. Importance has been attached to health effects, as these are the dominating effects in the external costs. Other effects are only mentioned on a superior level. The report points out different parameters, which are important to consider when externalities estimated for the same fuel cycle in different studies are compared. 8 studies have been chosen for further analysis and comparison in order to show the variation in external costs. The comparison shows the importance of possessing knowledge of which kind of methodologies have been used, which impacts are included etc. to explain why the numbers vary so much in different studies for the same fuel cycle. As an example a comparison of the impacts and damage costs related to air emissions has been made for three studies using different methodologies. The external costs are estimated for the same reference plant using the dispersion models, dose-response functions, impacts and monetary values from the three studies. The estimates from the three studies are compared two and two, and a more detailed analysis is performed in relation to human health, which is the dominating impact in all externality studies. (au) EFP-97. 29 tabs., 12 ills., 34 refs

  17. Differences in methodologies used for externality assessment. Why are the numbers different?

    Energy Technology Data Exchange (ETDEWEB)

    Schleisner, Lotte

    1999-06-01

    During the last few years, externalities related to power production technologies have been calculated making use of different methodologies. The external costs may turn out to be very different for the same fuel cycle depending on the methodology that has been used to assess the externalities. The report gives a review of different valuation issues, which are used in different externality studies and focuses on why the numbers often are different for the same fuel cycle, using different methodologies for assessment of the externalities. The review of externality valuation focuses in this report on the assessment of environmental externalities. Importance has been attached to health effects, as these are the dominating effects in the external costs. Other effects are only mentioned on a superior level. The report points out different parameters, which are important to consider when externalities estimated for the same fuel cycle in different studies are compared. 8 studies have been chosen for further analysis and comparison in order to show the variation in external costs. The comparison shows the importance of possessing knowledge of which kind of methodologies have been used, which impacts are included etc. to explain why the numbers vary so much in different studies for the same fuel cycle. As an example a comparison of the impacts and damage costs related to air emissions has been made for three studies using different methodologies. The external costs are estimated for the same reference plant using the dispersion models, dose-response functions, impacts and monetary values from the three studies. The estimates from the three studies are compared two and two, and a more detailed analysis is performed in relation to human health, which is the dominating impact in all externality studies. (au) EFP-97. 29 tabs., 12 ills., 34 refs.

  18. Literature review: Assessment of DWPF melter and melter off-gas system lifetime

    Energy Technology Data Exchange (ETDEWEB)

    Reigel, M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-07-30

    A glass melter for use in processing radioactive waste is a challenging environment for the materials of construction (MOC) resulting from a combination of high temperatures, chemical attack, and erosion/corrosion; therefore, highly engineered materials must be selected for this application. The focus of this report is to review the testing and evaluations used in the selection of the Defense Waste Processing Facility (DWPF), glass contact MOC specifically the Monofrax® K-3 refractory and Inconel® 690 alloy. The degradation or corrosion mechanisms of these materials during pilot scale testing and in-service operation were analyzed over a range of oxidizing and reducing flowsheets; however, DWPF has primarily processed a reducing flowsheet (i.e., Fe2+/ΣFe of 0.09 to 0.33) since the start of radioactive operations. This report also discusses the materials selection for the DWPF off-gas system and the corrosion evaluation of these materials during pilot scale testing and non-radioactive operations of DWPF Melter #1. Inspection of the off-gas components has not been performed during radioactive operations with the exception of maintenance because of plugging.

  19. Literature review: Assessment of DWPF melter and melter off-gas system lifetime

    Energy Technology Data Exchange (ETDEWEB)

    Reigel, M. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-07-30

    A glass melter for use in processing radioactive waste is a challenging environment for the materials of construction (MOC) resulting from a combination of high temperatures, chemical attack, and erosion/corrosion; therefore, highly engineered materials must be selected for this application. The focus of this report is to review the testing and evaluations used in the selection of the Defense Waste Processing Facility (DWPF), glass contact MOC specifically the Monofrax® K-3 refractory and Inconel® 690 alloy. The degradation or corrosion mechanisms of these materials during pilot scale testing and in-service operation were analyzed over a range of oxidizing and reducing flowsheets; however, DWPF has primarily processed a reducing flowsheet (i.e., Fe2+/ΣFe of 0.09 to 0.33) since the start of radioactive operations. This report also discusses the materials selection for the DWPF off-gas system and the corrosion evaluation of these materials during pilot scale testing and non-radioactive operations of DWPF Melter #1. Inspection of the off-gas components has not been performed during radioactive operations with the exception of maintenance because of plugging.

  20. Clinical governance and external audit.

    Science.gov (United States)

    Glazebrook, S G; Buchanan, J G

    2001-01-01

    This paper describes a model of clinical governance that was developed at South Auckland Health during the period 1995 to 2000. Clinical quality and safety are core objectives. A multidisciplinary Clinical Board is responsible for the development and publicising of sound clinical policies together with monitoring the effects of their implementation on quality and safety. The Clinical Board has several committees, including an organization-wide Continuous Quality Improvement Committee to enhance the explicit nature of the quality system in terms of structure, staff awareness and involvement, and to develop the internal audit system. The second stream stems from the Chief Medical Officer and clinical directors in a clinical management sense. The Audit Committee of the Board of Directors covers both clinical and financial audit. The reporting lines back to that committee are described and the role of the external auditor of clinical standards is explained. The aim has been to create a supportive culture where quality initiatives and innovation can flourish, and where the emphasis is not on censure but improvement.

  1. External auditory canal carcinoma treatment

    International Nuclear Information System (INIS)

    Matsuda, Yoichi; Ueda, Yoshihisa; Kurita, Tomoyuki; Nakashima, Tadashi

    2010-01-01

    External auditory canal (EAC) carcinomas are relatively rare conditions lack on established treatment strategy. We analyzed a treatment modalities and outcome in 32 cases of EAC squamous cell carcinoma treated between 1980 and 2008. Subjects-17 men and 15 women ranging from 33 to 92 years old (average: 66) were divided by Arriaga's tumor staging into 12 T1, 5 T2, 6 T3, and 9 T4. Survival was calculated by the Kaplan-Meier method. Disease-specific 5-year survival was 100% for T1, T2, 44% for T3, and 33% for T4. In contrast to 100% 5-year survival for T1+T2 cancer, the 5-year survival for T3+T4 cancer was 37% with high recurrence due to positive surgical margins. The first 22 years of the 29 years surveyed, we performed surgery mainly, and irradiation or chemotherapy was selected for early disease or cases with positive surgical margins as postoperative therapy. During the 22-years, 5-year survival with T3+T4 cancer was 20%. After we started superselective intra-arterial (IA) rapid infusion chemotherapy combined with radiotherapy in 2003, we achieved negative surgical margins for advanced disease, and 5-year survival for T3+T4 cancer rise to 80%. (author)

  2. The external costs of electricity

    International Nuclear Information System (INIS)

    Rabl, A.; Spadaro, J.V.

    2001-01-01

    This article presents an overview of the ExtrenE project (external costs of electricity) of the European Commission (EC). The damage caused by pollution has been calculated through analyses of the impact pathways which involve an analysis of the emission - dispersion - dose-response function - monetary estimation chain. The results are introduced for various cycles of combustible fuels (with several technological variants), indicating the confidence intervals. The cost of the damage is particularly high for coal. For example, for the coal-fired power stations in France (with the emission levels of 1995) it is approximately equal to the sales price of electricity. For natural gas, the cost of damage is approximately one-third that of coal. On the other hand, the damage costs for nuclear fuel and most forms of renewable energy are low, at a maximum just a few percent of the electricity price. The greatest part of these costs arises from health impact, particularly premature death. In order to avoid the controversy inherent in making a monetary assessment of mortality, especially if this is imposed upon future generations, the reduction in life expectancy due to the various combustible cycles is also indicated and the risks of nuclear energy are put into perspective via several comparisons. (authors)

  3. EXTERNAL ELEMENTS OF INTERCULTURAL MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Ruxandra GEORGESCU

    2017-12-01

    Full Text Available Because nowadays we attach a great importance to our look, this article wants to highlight certain aspects of intercultural management that are external to us, the personal label with which we "come into contact with the whole world” and also this article gives some suggestions that I want to consider for business success. As speakers of a language, we are both "producers" and "consumers" of it. In a sense, this is also the case for the dress code, the "language" of clothing: we dress in a certain way and this send messages to others; We perceive how others are dressed and so we receive messages from them. But there is no difference: we are not the ones who produce the signs. Beyond fashion, myths and motes, clothing, accessories, gesture, face expression, posture and body lines are the first elements that give visual identity to any person. In the business environment, as in the world of fashion, immediate visual identity is the one that generates the first impression.

  4. External plans for radiological emergency

    International Nuclear Information System (INIS)

    Suarez, G.; Vizuet G, J.; Benitez S, J.A.

    1999-01-01

    Since 1989, the National Institute of Nuclear Research in Mexico shares in the task of Food and Water Control corresponding to the FT-86 task force of External Plans for Radiological Emergency (PERE), in charge of the Veracruz Health Services. In the PERE preparation stage previous actions are necessary developed for the preparation and updating of this plan and the task organization with the purpose to maintaining standing and operable in any time and circumstance, the capability to response in the face of an emergency. This stage englobes activities which must be realized before to carry out the Plan as they are the specialized training of personnel which participates and the execution of exercises and simulacrums. Until 1998, training and exercises for this task had been realized under diverse possible sceneries but in conditions that simulated the presence of radioactive material. For this reason, it should be emphasized the training realized during the days 6th, 7th, 8th July, 1999, in the emergency planning zone of the Plan, which to carry out using radioactive material. The National Institute of Nuclear Research had in charge of the training. This work describes all the activities for the realization of this training. (Author)

  5. Bone scanning in severe external otitis

    International Nuclear Information System (INIS)

    Levin, W.J.; Shary, J.H. III; Nichols, L.T.; Lucente, F.E.

    1986-01-01

    Technetium99 Methylene Diphosphate bone scanning has been considered an early valuable tool to diagnose necrotizing progressive malignant external otitis. However, to our knowledge, no formal studies have actually compared bone scans of otherwise young, healthy patients with severe external otitis to scans of patients with clinical presentation of malignant external otitis. Twelve patients with only severe external otitis were studied with Technetium99 Diphosphate and were compared to known cases of malignant otitis. All scans were evaluated by two neuroradiologists with no prior knowledge of the clinical status of the patients. Nine of the 12 patients had positive bone scans with many scans resembling those reported with malignant external otitis. Interestingly, there was no consistent correlation between the severity of clinical presentation and the amount of Technetium uptake. These findings suggest that a positive bone scan alone should not be interpreted as indicative of malignant external otitis

  6. Human Sound Externalization in Reverberant Environments

    DEFF Research Database (Denmark)

    Catic, Jasmina

    In everyday environments, listeners perceive sound sources as externalized. In listening conditions where the spatial cues that are relevant for externalization are not represented correctly, such as when listening through headphones or hearing aids, a degraded perception of externalization may...... occur. In this thesis, the spatial cues that arise from a combined effect of filtering due to the head, torso, and pinna and the acoustic environment were analysed and the impact of such cues for the perception of externalization in different frequency regions was investigated. Distant sound sources...... were simulated via headphones using individualized binaural room impulse responses (BRIRs). An investigation of the influence of spectral content of a sound source on externalization showed that effective externalization cues are present across the entire frequency range. The fluctuation of interaural...

  7. IRIS Toxicological Review of Trichloroethylene (Interagency Science Consultation Draft)

    Science.gov (United States)

    On November 3, 2009, the Toxicological Review of Trichloroethylene and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White Hous...

  8. Energy security externalities and fuel cycle comparisons

    International Nuclear Information System (INIS)

    Bohi, D.; Toman, M.

    1994-01-01

    Externalities related to 'energy security' may be one way in which the full social costs of energy use diverge from the market prices of energy commodities. Such divergences need to be included in reckoning the full costs of different fuel cycles. In this paper we critically examine potential externalities related to energy security and issues related to the measurement of 2 these externalities, in the context of fuel cycle comparisons

  9. Measuring External Face Appearance for Face Classification

    OpenAIRE

    Masip, David; Lapedriza, Agata; Vitria, Jordi

    2007-01-01

    In this chapter we introduce the importance of the external features in face classification problems, and propose a methodology to extract the external features obtaining an aligned feature set. The extracted features can be used as input to any standard pattern recognition classifier, as the classic feature extraction approaches dealing with internal face regions in the literature. The resulting scheme follows a top-down segmentation approach to deal with the diversity inherent to the extern...

  10. Risk analysis of external radiation therapy

    International Nuclear Information System (INIS)

    Arvidsson, Marcus

    2011-09-01

    External radiation therapy is carried out via a complex treatment process in which many different groups of staff work together. Much of the work is dependent on and in collaboration with advanced technical equipment. The purpose of the research task has been to identify a process for external radiation therapy and to identify, test and analyze a suitable method for performing risk analysis of external radiation therapy

  11. Externality-correcting taxes and regulation

    OpenAIRE

    Christiansen, V.; Smith, S.

    2009-01-01

    Much of the literature on externalities has considered taxes and direct regulation as alternative policy instruments. Both instruments may in practice be imperfect, reflecting informational deficiencies and other limitations. We analyse the use of taxes and regulation in combination, to control externalities arising from individual consumption behaviour. We consider cases where taxes are either imperfectly differentiated to reflect individual differences in externalities, or where some consum...

  12. Energy security externalities and fuel cycle comparisons

    Energy Technology Data Exchange (ETDEWEB)

    Bohi, D; Toman, M

    1994-07-01

    Externalities related to 'energy security' may be one way in which the full social costs of energy use diverge from the market prices of energy commodities. Such divergences need to be included in reckoning the full costs of different fuel cycles. In this paper we critically examine potential externalities related to energy security and issues related to the measurement of 2 these externalities, in the context of fuel cycle comparisons.

  13. Early discharge after external anal sphincter repair

    DEFF Research Database (Denmark)

    Rosenberg, J; Kehlet, H

    1999-01-01

    PURPOSE: The aim of this study was to describe an accelerated-stay program for repair of the external anal sphincter. METHODS: Twenty consecutive patients undergoing overlapping repair of the external anal sphincter were included in the study. Effect parameters were length of hospitalization....... CONCLUSION: We have described a safe accelerated-stay program (24 to 48 hours) for overlapping repair of external anal sphincter....

  14. External quality audit programmes for radiotherapy dosimetry and equipment

    International Nuclear Information System (INIS)

    Thwaites, D.I.

    1997-01-01

    It is widely accepted that individual radiotherapy centres should have in place a comprehensive quality assurance programme on all the necessary steps for the delivery of safe accurate treatment. As regards the performance of radiotherapy equipment and dosimetry, the most widely used process of external checking has been dosimetry intercomparison, comparing independently measured doses to locally stated doses in a variety of conditions. These have been at a number of different levels: from basic beam calibration; up to and including exercises employing anatomic or pseudo-anatomic phantoms and incorporating tests of treatment planning equipment and procedures. Some of these have been one-off exercises, whilst others are continuing, or have given rise to on-going quality audit programmes on a national (or wider) basis. A number of these have evolved, or are evolving, into audits which include external checking of the achievement of standards in performance of treatment equipment, as well as in the dosimetry in each institution involved. The principles and methodologies of the various types of external checking programmes for treatment equipment and dosimetry are reviewed, covering the experimental approaches and the tolerances applied. What is included in a given programme will, of necessity, depend on the resources available and the purpose of the exercise. Methods and tolerances must be matched to endpoint. Tolerance levels must take into account the experimental uncertainties of the measurement methods employed. Finally, external audit can only be used to complement, and in conjunction with, institutional quality assurance programmes and not as a substitute for them

  15. Problems of quantum electrodynamics with external field creating pairs

    International Nuclear Information System (INIS)

    Fradkin, E.S.; Gitman, D.M.

    1979-11-01

    This paper is a preliminary version of a review of the results obtained by the authors and their collaborators which mainly concern problems of quantum electrodynamics with the pair-creating external field. In this paper the Furry picture is constructed for quantum electrodynamics with the pair-creating external field. It is shown, that various Green functions in the external field arise in the theory in a natural way. Special features of usage of the unitarity conditions for calculating the total probabilities of transitions are discussed. Perturbation theory for determining the mean electromagnetic field is constructed. Effective Lagrangians for pair-creating fields are built. One of the possible ways to introduce external field in quantum electrodynamics is considered. All the Green functions arising in the theory suggested are calculated for a constant field and a plane wave field. For the case of the electric field the total probability of creation of pairs from the vacuum accompanied by the photon irradiation and the total probability of transition from a single-electron state accompanied by the photon irradiation and creation of pairs are obtained by using the formulated rules for calculating the total probabilities of transitions. (author)

  16. Proceedings: National conference on environmental externalities

    International Nuclear Information System (INIS)

    1990-01-01

    This report is the proceedings of the National Conference on Environmental Externalities. A environmental externality is the environmental impact of a process or a plant that society must endure. It is a social cost and is paid, but not by the company who produced it or the company's customers who endure it. The main purpose of this report is to gather the many designs and ideas of how and why to internalize the externalities into the pricing systems of the public utility commissions, especially that of the electric utilities. Economic and sociological aspects of the internalization of these externalities are given in these proceedings. Individual papers are processed separately for databases. (MB)

  17. External proton and Li beams

    International Nuclear Information System (INIS)

    Schuff, Juan A.; Burlon, Alejandro A.; Debray, Mario E.; Kesque, Jose M.; Kreiner, Andres J.; Stoliar, Pablo A.; Naab, Fabian; Ozafran, Mabel J.; Vazquez, Monica E.; Perez de la Hoz, A.; Somacal, Hector; Valda, Alejandro; Canevas, S.; Ruffolo, M.; Tasat, D.R.; Muhlmann, M. C.

    2000-01-01

    In the frame of a feasibility study to introduce proton therapy in Argentina in a collaborative agreement between the Physics and Radiobiology Departments of the National Atomic Energy Commission or Argentina and the Centre de Protontherapie de Orsay, France, external proton and Li beams were produced at the TANDAR accelerator in Buenos Aires. The specific aim of this work was to start radiobiology studies on cell cultures and small laboratory animals. In particular we seek to determine here the relative biological effectiveness, RBE, for proton and Li beams as a function of energy for different tumor and normal cell lines. The 24 MeV proton beam was diffused using a 25 μm gold foil and extracted through a Kapton window to obtain a homogeneous field (constant to 95%) of about 7 cm in diameter. Measurements were carried out with quasi-monoenergetic beams (of 20.2 ± 0.07 MeV, 2.9 ± 0.10 MeV y 1.5 ± 0.1 MeV for protons and 21.4 ± 0.4 MeV for Lithium). Proton fluence and Bragg peaks were measured. The dose delivered in each case was monitored on-line with a calibrated transmission ionization chamber. Three cell lines PDV, PDVC 57 and V 79 (as a reference) were irradiated with γ-rays, proton and lithium beams with linear energy transfer (LET) from 2 to 100 keV/μm. RBE values in the range of 1.2-5.9 were obtained. In addition preliminary studies on chromosomal aberrations and viability of alveolar macrophages were carried out. (author)

  18. Energy policy and externalities: an overview

    International Nuclear Information System (INIS)

    Pearce, D.

    2002-01-01

    Substantial progress has been made in estimating the monetary value of the environmental impacts of different energy systems. Perhaps the best known study in Europe is that sponsored by the European Commission and known as the ExternE programme. In the USA a comparable project is that jointly sponsored by the US Department of Energy and the European Commission. There are many others. In each case what is sought is a monetary value of an environmental impact arising from a unit of energy, usually standardised as a kilowatt hour. These environmental impacts are usually termed 'externalities'. An externality exists if two conditions are met. First, some negative (or positive) impact is generated by an economic activity and imposed on third parties. Second, that impact must not be priced in the market place, i.e. if the effect is negative, no compensation is paid by the generator of the externality to the sufferer. If the effect is positive, the generator of the externality must not appropriate the gains to the third party, e.g. via some price that is charged. In the energy externality literature, the procedure of expressing the externalities in, say, cents or milli-euros (1000 th of an Euro = m-euro) per kWh results in an 'adder'. An adder is simply the unit externality cost added to the standard resource cost of energy. Thus, if an electricity source costs X m/euros to produce or deliver, the final social cost of it is (X+y) m-euros where y is the externality adder. While externality adders have been researched most in the context of energy, they are increasingly being estimated for other economic sectors, notably transport and agriculture. This paper presents the uses of such figures. (author)

  19. Uterine cervix cancer treatment in IIB, IIIA and IIIB stages with external radiotherapy versus external radiotherapy and scintiscanning of low dose. ION SOLCA. Years 1998-2000

    International Nuclear Information System (INIS)

    Sanchez, Doris; Falquez, Roberto

    2002-01-01

    We realized study of retrospective accomplished in course of years 1998-2000, reviewing clinical charts of statistical department of ION SOLCA. We reviewed 544 cases in 1998, 603 patients in 1999, and 630 cases in 2000. In the radiotherapy service, 133 patients received treatment with external radiotherapy between February 1998 to February 1999 in IIB, IIIA, IIIB stages and only 80 patients were treated with external radiotherapy and scintiscanning of low dose rate in the same stages between March 1999 to March 2000. (The author)

  20. Lower ionosphere response to external forcing: A brief review

    Czech Academy of Sciences Publication Activity Database

    Laštovička, Jan

    2009-01-01

    Roč. 43, č. 1 (2009), s. 1-14 ISSN 0273-1177 R&D Projects: GA ČR GA205/07/1367; GA ČR GA205/08/1356 Institutional research plan: CEZ:AV0Z30420517 Keywords : lower ionosphere * space weather forcing * solar activity * solar forcing * atmospheric waves * atmospheric forcing Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 1.079, year: 2009